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Sample records for colony-level macronutrient regulation

  1. Circadian Regulation of Macronutrient Absorption.

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    Hussain, M Mahmood; Pan, Xiaoyue

    2015-12-01

    Various intestinal functions exhibit circadian rhythmicity. Disruptions in these rhythms as in shift workers and transcontinental travelers are associated with intestinal discomfort. Circadian rhythms are controlled at the molecular level by core clock and clock-controlled genes. These clock genes are expressed in intestinal cells, suggesting that they might participate in the circadian regulation of intestinal functions. A major function of the intestine is nutrient absorption. Here, we will review absorption of proteins, carbohydrates, and lipids and circadian regulation of various transporters involved in their absorption. A better understanding of circadian regulation of intestinal absorption might help control several metabolic disorders and attenuate intestinal discomfort associated with disruptions in sleep-wake cycles.

  2. Novel Molecules Regulating Energy Homeostasis: Physiology and Regulation by Macronutrient Intake and Weight Loss

    Directory of Open Access Journals (Sweden)

    Anna Gavrieli

    2016-09-01

    Full Text Available Excess energy intake, without a compensatory increase of energy expenditure, leads to obesity. Several molecules are involved in energy homeostasis regulation and new ones are being discovered constantly. Appetite regulating hormones such as ghrelin, peptide tyrosine-tyrosine and amylin or incretins such as the gastric inhibitory polypeptide have been studied extensively while other molecules such as fibroblast growth factor 21, chemerin, irisin, secreted frizzle-related protein-4, total bile acids, and heme oxygenase-1 have been linked to energy homeostasis regulation more recently and the specific role of each one of them has not been fully elucidated. This mini review focuses on the above mentioned molecules and discusses them in relation to their regulation by the macronutrient composition of the diet as well as diet-induced weight loss.

  3. Clock is important for food and circadian regulation of macronutrient absorption in mice.

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    Pan, Xiaoyue; Hussain, M Mahmood

    2009-09-01

    Clock genes respond to external stimuli and exhibit circadian rhythms. This study investigated the expression of clock genes in the small intestine and their contribution in the regulation of nutrient absorption by enterocytes. We examined expression of clock genes and macronutrient transport proteins in the small intestines of wild-type and Clock mutant (Clk(mt/mt)) mice with free or limited access to food. In addition, we studied absorption of macronutrients in these mice. Intestinal clock genes show circadian expression and respond to food entrainment in wild-type mice. Dominant negative Clock in Clk(mt/mt) mice disrupts circadian expression and food entrainment of clock genes. The absorption of lipids and monosaccharides was high in Clk(mt/mt) mice whereas peptide absorption was reduced. Molecular studies revealed that Clock regulates several transport proteins involved in nutrient absorption. Clock plays an important role in light and food entrainment of intestinal functions by regulating nutrient transport proteins. Disruptions in intestinal circadian activity may contribute to hyperlipidemia and hyperglycemia.

  4. A Novel Rice Gene, NRR Responds to Macronutrient Deficiency and Regulates Root Growth

    Institute of Scientific and Technical Information of China (English)

    Yu-Man Zhang; Xiao-Ying Chen; Yong-Sheng Yan; Li-Na Wang; Kun Yang; Na Xiao; Yun-Feng Liu; Ya-Ping Fu; Zong-Xiu Sun; Rong-Xiang Fang

    2012-01-01

    To better understand the response of rice to nutrient stress,we have taken a systematic approach to identify rice genes that respond to deficiency of macronutrients and affect rice growth.We report here the expression and biological functions of a previously uncharacterized rice gene that we have named NRR (nutrition response and root growth).NRR is alternatively spliced,producing two 5′-coterminal transcripts,NRRa and NRRb,encoding two proteins of 308 and 223 aa,respectively.Compared to NRRb,NRRa possesses an additional CCT domain at the C-terminus.Expression of NRR in rice seedling roots was significantly influenced by deficiency of macronutrients.Knock-down of expression of NRRa or NRRb by RNA interference resulted in enhanced rice root growth.By contrast,overexpression of NRRa in rice exhibited significantly retarded root growth.These results revealed that both NRRa and NRRb played negative regulatory roles in rice root growth.Our findings suggest that NRRa and NRRb,acting as the key components,modulate the rice root architecture with the availability of macronutrients.

  5. Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism.

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    Yon, Marianne A; Mauger, Suzanna L; Pickavance, Lucy C

    2013-05-01

    Of the environmental factors which have an impact on body weight, nutrients are most influential. Within normal limits, hypothalamic and related neuronal populations correct perturbations in energy metabolism, to return the body to its nutritional set-point, either through direct response to nutrients or indirectly via peripheral appetite signals. Excessive intake of certain macronutrients, such as simple carbohydrates and SFA, can lead to obesity and attendant metabolic dysfunction, also reflected in alterations in structural plasticity, and, intriguingly,neurogenesis, in some of these brain regions. Neurogenesis, previously thought to occur only in the embryo, is now known to take place in the adult brain, dependent on numerous stimulating and inhibiting factors, including dietary components. Because of classic associations between neurogenesis and the hippocampus, in learning and cognition, this brain region has also been the focus of attention in the study of links between diet and neurogenesis. Recently, however, a more complete picture of this relationship has been building: not only has the hypothalamus been shown to satisfy the criteria for a neurogenic niche, but appetite-related mediators, including circulating hormones, such as leptin and ghrelin, pro-inflammatory cytokines and the endocannabinoid intracellular messengers, are also being examined for their potential role in mediating neurogenic responses to macronutrients. The present review draws together these observations and investigates whether n-3 PUFA may exert their attenuating effects on body weight through the stimulation of adult neurogenesis. Exploration of the effects of nutraceuticals on neurogenic brain regions may encourage the development of new rational therapies in the fight against obesity.

  6. Individual variation in macronutrient regulation measured by proton magnetic resonance spectroscopy of human plasma.

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    Park, Youngja; Kim, Seoung Bum; Wang, Bing; Blanco, Roberto A; Le, Ngoc-Anh; Wu, Shaoxiong; Accardi, Carolyn J; Alexander, R Wayne; Ziegler, Thomas R; Jones, Dean P

    2009-07-01

    Proton nuclear magnetic resonance ((1)H-NMR) spectroscopy of plasma provides a global metabolic profiling method that shows promise for clinical diagnostics. However, cross-sectional studies are complicated by a lack of understanding of intraindividual variation, and this limits experimental design and interpretation of data. The present study determined the diurnal variation detected by (1)H NMR spectroscopy of human plasma. Data reduction methods revealed three time-of-day metabolic patterns, which were associated with morning, afternoon, and night. Major discriminatory regions for these time-of-day patterns included the various kinds of lipid signals (-CH(2)- and -CH(2)OCOR), and the region between 3 and 4 ppm heavily overlapped with amino acids that had alpha-CH and alpha-CH(2). The phasing and duration of time-of-day patterns were variable among individuals, apparently because of individual difference in food processing/digestion and absorption and clearance of macronutrient energy sources (fat, protein, carbohydrate). The times of day that were most consistent among individuals, and therefore most useful for cross-sectional studies, were fasting morning (0830-0930), postprandial afternoon (1430-1630), and nighttime samples (0430-0530). Importantly, the integrated picture of metabolism provided by (1)H-NMR spectroscopy of plasma suggests that this approach is suitable to study complex regulatory processes, including eating patterns/eating disorders, upper gastrointestinal functions (gastric emptying, pancreatic, biliary functions), and absorption/clearance of macronutrients. Hence, (1)H-NMR spectroscopy of plasma could provide a global metabolic tolerance test to assess complex processes involved in disease, including eating disorders and the range of physiological processes causing dysregulation of energy homeostasis.

  7. Acute regulation of IGF-I by alterations in post-exercise macronutrients

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    This investigation sought to examine the contributions of exercise and nutrient replenishment on in vivo regulation of the insulin-like growth factor-I (IGF-I) axis components. Eight college-aged males completed three high-intensity interval training (HIIT) protocols followed by three post-exercise ...

  8. Aluminum Enhances Growth and Sugar Concentration, Alters Macronutrient Status and Regulates the Expression of NAC Transcription Factors in Rice

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    Moreno-Alvarado, Marcos; García-Morales, Soledad; Trejo-Téllez, Libia Iris; Hidalgo-Contreras, Juan Valente; Gómez-Merino, Fernando Carlos

    2017-01-01

    Aluminum (Al) is a beneficial element for some plant species, especially when used at low concentrations. Though some transcription factors are induced by exposure to this element, no data indicate that Al regulates the expression of NAC genes in rice. In this study we tested the effect of applying 200 μM Al on growth, chlorophyll, amino acids, sugars, macronutrient concentration and regulation of NAC transcription factors gene expression in 24-day-old plants of four rice (Oryza sativa ssp. indica) cultivars: Cotaxtla, Tres Ríos, Huimanguillo and Temporalero, grown hydroponically under greenhouse conditions. Twenty days after treatment, we observed that Al enhanced growth in the four cultivars studied. On average, plants grown in the presence of Al produced 140% more root dry biomass and were 30% taller than control plants. Cotaxtla and Temporalero showed double the root length, while Huimanguillo and Cotaxtla had three times more root fresh biomass and 2.5 times more root dry biomass. Huimanguillo plants showed 1.5 times more shoot height, while Cotaxtla had almost double the root dry biomass. With the exception of Tres Ríos, the rest of the cultivars had almost double the chlorophyll concentration when treated with Al, whereas amino acid and proline concentrations were not affected by Al. Sugar concentration was also increased in plants treated with Al, almost 11-fold in comparison to the control. Furthermore, we observed a synergic response of Al application on P and K concentration in roots, and on Mg concentration in shoots. Twenty-four hours after Al treatment, NAC transcription factors gene expression was measured in roots by quantitative RT-PCR. Of the 57 NAC transcription factors genes primer-pairs tested, we could distinguish that 44% (25 genes) showed different expression patterns among rice cultivars, with most of the genes induced in Cotaxtla and Temporalero plants. Of the 25 transcription factors up-regulated, those showing differential expression

  9. Bumble bees regulate their intake of essential protein and lipid pollen macronutrients.

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    Vaudo, A D; Stabler, D; Patch, H M; Tooker, J F; Grozinger, C M; Wright, G A

    2016-12-15

    Bee population declines are linked to the reduction of nutritional resources due to land-use intensification, yet we know little about the specific nutritional needs of many bee species. Pollen provides bees with their primary source of protein and lipids, but nutritional quality varies widely among host-plant species. Therefore, bees might have adapted to assess resource quality and adjust their foraging behavior to balance nutrition from multiple food sources. We tested the ability of two bumble bee species, Bombus terrestris and Bombus impatiens, to regulate protein and lipid intake. We restricted B. terrestris adults to single synthetic diets varying in protein:lipid ratios (P:L). The bees over-ate protein on low-fat diets and over-ate lipid on high-fat diets to reach their targets of lipid and protein, respectively. The bees survived best on a 10:1 P:L diet; the risk of dying increased as a function of dietary lipid when bees ate diets with lipid contents greater than 5:1 P:L. Hypothesizing that the P:L intake target of adult worker bumble bees was between 25:1 and 5:1, we presented workers from both species with unbalanced but complementary paired diets to determine whether they self-select their diet to reach a specific intake target. Bees consumed similar amounts of proteins and lipids in each treatment and averaged a 14:1 P:L for B. terrestris and 12:1 P:L for B. impatiens These results demonstrate that adult worker bumble bees likely select foods that provide them with a specific ratio of P:L. These P:L intake targets could affect pollen foraging in the field and help explain patterns of host-plant species choice by bumble bees. © 2016. Published by The Company of Biologists Ltd.

  10. Short-term feed intake is regulated by macronutrient oxidation in lactating Holstein cows.

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    Derno, M; Nürnberg, G; Schön, P; Schwarm, A; Röntgen, M; Hammon, H M; Metges, C C; Bruckmaier, R M; Kuhla, B

    2013-02-01

    In addition to plasma metabolites and hormones participating as humoral signals in the control of feed intake, oxidative metabolic processes in peripheral organs also generate signals to terminate feeding. Although the degree of oxidation over longer periods is relatively constant, recent work suggests that the periprandial pattern of fuel oxidation is involved in regulating feeding behavior in the bovine. However, the association between periprandial oxidative metabolism and feed intake of dairy cows has not yet been studied. Therefore, the aim of this study was to elucidate possible associations existing between single feed intake events and whole-body net fat and net carbohydrate oxidation as well as their relation to plasma metabolite concentrations. To this end, 4 late-lactating cows equipped with jugular catheters were kept in respiratory chambers with continuous and simultaneous recording of gas exchange and feed intake. Animals were fed ad libitum (AL) for 24h and then feed restricted (RE) to 50% of the previous AL intake for a further 24h. Blood samples were collected hourly to analyze β-hydroxybutyrate (BHBA), glucose, nonesterified fatty acids (NEFA), insulin, and acylated ghrelin concentrations. Cross-correlation analysis revealed an offset ranging between 30 and 42 min between the maximum of a feed intake event and the lowest level of postprandial net fat oxidation (FOX(net)) and the maximum level of postprandial net carbohydrate oxidation (COX(net)), respectively. During the AL period, FOX(net) did not increase above -0.2g/min, whereas COX(net) did not decrease below 6g/min before the start of the next feed intake event. A strong inverse cross-correlation was obtained between COX(net) and plasma glucose concentration. Direct cross-correlations were observed between COXnet and insulin, between heat production and BHBA, between insulin and glucose, and between BHBA and ghrelin. We found no cross-correlation between FOX(net) and NEFA. During RE, FOX

  11. Macronutrient composition of the diet affects the feeding-mediated down regulation of autophagy in muscle of rainbow trout (O. mykiss.

    Directory of Open Access Journals (Sweden)

    Ikram Belghit

    Full Text Available Autophagy functions as an important catabolic mechanism by mediating the turnover of intracellular organelles and protein complexes through a lysosome dependent degradative pathway. Although the induction of autophagy by starvation has been extensively studied, we still know very little about how autophagy is regulated under normal nutritional conditions. The purpose of the present study was to characterize both in vivo and in vitro the response of the autophagy-lysosomal degradative pathway to nutrient (amino acids and carbohydrates availability in the muscle of the carnivorous rainbow trout. We report that meal feeding is accompanied by a rapid activation of Akt, FoxO1 and the Target of Rapamycin (TOR signaling pathways and a concomitant decrease of autophagosome formation. We also show that this effect occurs only when the proportion of dietary proteins increases at the expense of carbohydrates. Concurrently, our in vitro study on primary culture of trout muscle cells demonstrates an opposite effect of amino acids and glucose on the regulation of autophagy-lysosomal pathways. More specifically, the addition of amino acids in cell culture medium inhibited the formation of autophagosomes, whereas the addition of glucose had an opposite effect. The effect of amino acids was accompanied by an activation of TOR, considered as an important regulator of autophagosomal formation. However, the mechanisms involved in the effect of glucose were independent of Akt, TOR and AMPK and remain to be determined. Together, these results demonstrated the specific role of macronutrients as well as that of their interactions in the regulation of autophagy and highlight the interest to consider the macronutrient composition of the diets in the control of this degradative pathway.

  12. Effects of deficiency and excess of zinc on morphophysiological traits and spatiotemporal regulation of zinc-responsive genes reveal incidence of cross talk between micro- and macronutrients.

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    Jain, Ajay; Sinilal, Bhaskaran; Dhandapani, Gurusamy; Meagher, Richard B; Sahi, Shivendra V

    2013-05-21

    Zinc (Zn) is an essential micronutrient which affects plant growth and development in deficiency and can be toxic when present in excess. In Arabidopsis thaliana , different families of cation transporters play pivotal roles in Zn homeostasis. In the present study, we evaluated the effects of Zn in its deficiency (0 μM; Zn-) and excess (75 μM; Zn++) on various morphophysiological and molecular traits. Primary root length was reduced in Zn- seedlings, whereas there were significant increases in the number and length of lateral roots under Zn- and Zn++ conditions, respectively. Concentration of various macro- and microelements showed variations under different Zn regimes and notable among them was the reduced level of iron (Fe) in Zn++ seedlings compared to Zn+. Certain members of the ZIP family (ZIP4, ZIP9, and ZIP12) showed significant induction in roots and shoots of the Zn- seedlings. Their suppression under Zn++ condition indicated their transcriptional regulation by Zn and their roles in the maintenance of its homeostasis. Zn-deficiency-mediated induction of HMA2 in roots and shoots suggested its role in effluxing Zn into xylem for long-distance transport. Attenuation in the expression of Fe-responsive FRO2 and IRT1 in Zn- roots and their induction in Zn++ roots provided empirical evidence toward the prevalence of a cross talk between Zn and Fe homeostasis. Variable effects of Zn- and Zn++ on the expression of subset of genes involved in the homeostasis of phosphate (Pi), potassium (K), and sulfur (S) further highlighted the prevalence of cross talk between the sensing and signaling cascades of Zn and macronutrients. Further, the inducibility of ZIP4 and ZIP12 in response to cadmium (cd) treatment could be harnessed by tailoring them in homologous or heterologous plant system for removing pollutant toxic heavy metals from the environment.

  13. Effect of macronutrient composition on short-term food intake and weight loss.

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    Bellissimo, Nick; Akhavan, Tina

    2015-05-01

    The purpose of this review is to describe the role of macronutrient composition on the suppression of short-term food intake (FI) and weight loss. The effects of macronutrient composition on short-term FI will be reviewed first, followed by a brief examination of longer-term clinical trials that vary in effects of dietary macronutrient composition on weight loss. The objectives were: 1) to examine the effect of macronutrient composition on the suppression of short-term FI, 2) to determine whether some macronutrient sources suppress FI beyond their provision of energy, 3) to assess the combined effects of macronutrients on FI and glycemic response, and 4) to determine whether knowledge of the effect of macronutrients on short-term FI has led to greater success in spontaneous weight loss, adherence to energy-restricted diets, and better weight maintenance after weight loss. Although knowledge of macronutrient composition on short-term FI regulation has advanced our understanding of the role of diet composition on energy balance, it has yet to lead to greater success in long-term weight loss and weight maintenance. It is clear from this review that many approaches based on manipulating dietary macronutrient composition can help people lose weight as long as they follow the diets. However, only by evaluating the interaction between the physiologic systems that govern FI and body weight may the benefits of dietary macronutrient composition be fully realized. © 2015 American Society for Nutrition.

  14. The evolution of colony-level development in the Siphonophora (Cnidaria:Hydrozoa).

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    Dunn, Casey W; Wagner, Günter P

    2006-12-01

    Evolutionary developmental biology has focused almost exclusively on multicellular organisms, but there are other relevant levels of biological organization that have remained largely neglected. Animal colonies are made up of multiple physiologically integrated and genetically identical units called zooids that are each homologous to solitary, free-living animals. Siphonophores, a group of pelagic hydrozoans (Cnidaria), have the most complex colony-level organization of all animals. Here the colony-level development of five siphonophore species, strategically sampled across the siphonophore phylogeny, is described from specimens collected using deep-sea submersibles and by self-contained underwater breathing apparatus diving. These species include three cystonects, Bathyphysa sibogae, Rhizophysa filiformis, and Rhizophysa eysenhardti, and two "physonects", Agalma elegans and Nanomia bijuga. These data, together with previous findings, are analyzed in a phylogenetic framework to reconstruct key features of the history of colony-level organization and development in the Siphonophora. It is shown that gonodendra and gastrozooids of the examined cystonects arise as independent buds directly on the stem, whereas probud subdivision (the origin of feeding, reproductive, and other zooids from a single bud) is a synapomorphy of the Codonophora. The origin of probud subdivision is associated with the origin of cormidia as integrated units of colony organization, and may have allowed for greater morphological and ecological diversification in the Codonophora relative to the Cystonectae. It is also found that symmetry is labile in siphonophores, with multiple gains and/or losses of directional asymmetry in the group. This descriptive work will enable future mechanistic and molecular studies of colony-level development in the siphonophores.

  15. Effect of macronutrient composition of the diet on the regulation of lipolysis in adipose tissue at rest and during exercise: microdialysis study.

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    Suljkovicova, Hana; Marion-Latard, Fabrice; Hejnova, Jindra; Majercik, Marek; Crampes, François; De Glisezinski, Isabelle; Berlan, Michel; Rivière, Daniel; Stich, Vladimir

    2002-10-01

    The aim of the present study was to elucidate, using a microdialysis technique, whether modifications in the proportion of fat in the diet influence lipid mobilization from adipose tissue in situ. Nine healthy volunteers (age, 23.4 +/- 0.2 years; body mas index [BMI], 23.5 +/- 1.6 kg/m(2)) were fed, in random order, with a high-fat diet (HFD) (65% of energy content fat, 15% protein, 20% carbohydrate) or a high-carbohydrate diet (HCD) (70% carbohydrate, 15% protein, 15% fat) for 5 days, with a washout period of 10 days between the diets. Subjects were studied in the fasting state on the morning following days 4 and 5 of each diet. We measured the concentration of extracellular glycerol (EGC) in adipose tissue in response to (1) pharmacologic stimulation with isoprenaline (1 and 10 micromol/L) in situ, (2) stimulation with intravenous infusion of epinephrine (0.0375 microg/min/kg body weight), and (3) submaximal aerobic exercise (50% V*O2max, 60-minute duration). No effect of the diet composition was found in the increases of EGC in response to isoprenaline (area under the curve [AUC]: HFD, 1,534 +/- 370 micromol/90 min; HCD, 1,108 +/- 465 micromol/90 min; not significant [NS]) or epinephrine stimulations (AUC: HFD, 190 +/- 92 micromol/30 min; HCD, 251 +/- 298 micromol/30 min; NS). The exercise-induced increase in EGC was higher during the HFD (AUC: HFD, 1,641 +/- 181 micromol/60 min; HCD, 963 +/- 156 micromol/60 min; P <.05) and was associated with a higher exercise-induced response of norepinephrine (P <.05) and epinephrine (P =.056) and lower insulinemia during exercise. The results suggest that macronutrient composition of diet does not affect the beta-adrenergic responsiveness of adipose tissue to catecholamine action at rest. During exercise, the HFD promotes higher lipolysis in adipose tissue and this is associated with a higher catecholamine response and lower insulinemia.

  16. Summer and fall ants have different physiological responses to food macronutrient content.

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    Cook, Steven C; Eubanks, Micky D; Gold, Roger E; Behmer, Spencer T

    2016-04-01

    Seasonally, long-lived animals exhibit changes in behavior and physiology in response to shifts in environmental conditions, including food abundance and nutritional quality. Ants are long-lived arthropods that, at the colony level, experience such seasonal shifts in their food resources. Previously we reported summer- and fall-collected ants practiced distinct food collection behavior and nutrient intake regulation strategies in response to variable food protein and carbohydrate content, despite being reared in the lab under identical environmental conditions and dietary regimes. Seasonally distinct responses were observed for both no-choice and choice dietary experiments. Using data from these same experiments, our objective here is to examine colony and individual-level physiological traits, colony mortality and growth, food processing, and worker lipid mass, and how these traits change in response to variable food protein-carbohydrate content. For both experiments we found that seasonality per se exerted strong effects on colony and individual level traits. Colonies collected in the summer maintained total worker mass despite high mortality. In contrast, colonies collected in the fall lived longer, and accumulated lipids, including when reared on protein-biased diets. Food macronutrient content had mainly transient effects on physiological responses. Extremes in food carbohydrate content however, elicited a compensatory response in summer worker ants, which processed more protein-biased foods and contained elevated lipid levels. Our study, combined with our previously published work, strongly suggests that underlying physiological phenotypes driving behaviors of summer and fall ants are likely fixed seasonally, and change circannually. Published by Elsevier Ltd.

  17. Macronutrient Intake for Physical Activity

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    Buford, Thomas

    Proper nutrition is an essential element of athletic performance, body composition goals, and general health. Although natural variability among persons makes it impossible to create a single diet that can be recommended to all; examining scientific principles makes it easier for athletes and other physically active persons to eat a diet that prepares them for successful training and/or athletic competition. A proper nutritional design incorporates these principles and is tailored to the individual. It is important for the sports nutritionist, coach, and athlete to understand the role that each of the macronutrients plays in an active lifestyle. In addition, keys to success include knowing how to determine how many calories to consume, the macronutrient breakdown of those calories, and proper timing to maximize the benefits needed for the individual's body type and activity schedule.

  18. Colony Level Prevalence and Intensity of Nosema ceranae in Honey Bees (Apis mellifera L.)

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    Lucas, Hannah M.; Webster, Thomas C.; Sagili, Ramesh R.

    2016-01-01

    Nosema ceranae is a widely prevalent microsporidian parasite in the western honey bee. There is considerable uncertainty regarding infection dynamics of this important pathogen in honey bee colonies. Understanding the infection dynamics at the colony level may aid in development of a reliable sampling protocol for N. ceranae diagnosis, and provide insights into efficient treatment strategies. The primary objective of this study was to characterize the prevalence (proportion of the sampled bees found infected) and intensity (number of spores per bee) of N. ceranae infection in bees from various age cohorts in a colony. We examined N. ceranae infection in both overwintered colonies that were naturally infected with N. ceranae and in quadruple cohort nucleus colonies that were established and artificially inoculated with N. ceranae. We also examined and quantified effects of N. ceranae infection on hypopharyngeal gland protein content and gut pH. There was no correlation between the prevalence and intensity of N. ceranae infection in composite samples (pooled bee samples used for analysis). Our results indicated that the prevalence and intensity of N. ceranae infection is significantly influenced by honey bee age. The N. ceranae infection prevalence values from composite samples of background bees (unmarked bees collected from four different locations in a colony) were not significantly different from those pertaining to marked-bee age cohorts specific to each sampling date. The foraging-aged bees had a higher prevalence of N. ceranae infection when compared to nurse-aged bees. N. ceranae did not have a significant effect on hypopharyngeal gland protein content. Further, there was no significant difference in mean gut pH of N. ceranae infected bees and non-infected bees. This study provides comprehensive insights into N. ceranae infection dynamics at the colony level, and also demonstrates the effects of N. ceranae infection on hypopharyngeal gland protein content and

  19. Combined pesticide exposure severely affects individual- and colony-level traits in bees.

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    Gill, Richard J; Ramos-Rodriguez, Oscar; Raine, Nigel E

    2012-11-01

    Reported widespread declines of wild and managed insect pollinators have serious consequences for global ecosystem services and agricultural production. Bees contribute approximately 80% of insect pollination, so it is important to understand and mitigate the causes of current declines in bee populations . Recent studies have implicated the role of pesticides in these declines, as exposure to these chemicals has been associated with changes in bee behaviour and reductions in colony queen production. However, the key link between changes in individual behaviour and the consequent impact at the colony level has not been shown. Social bee colonies depend on the collective performance of many individual workers. Thus, although field-level pesticide concentrations can have subtle or sublethal effects at the individual level, it is not known whether bee societies can buffer such effects or whether it results in a severe cumulative effect at the colony level. Furthermore, widespread agricultural intensification means that bees are exposed to numerous pesticides when foraging, yet the possible combinatorial effects of pesticide exposure have rarely been investigated. Here we show that chronic exposure of bumblebees to two pesticides (neonicotinoid and pyrethroid) at concentrations that could approximate field-level exposure impairs natural foraging behaviour and increases worker mortality leading to significant reductions in brood development and colony success. We found that worker foraging performance, particularly pollen collecting efficiency, was significantly reduced with observed knock-on effects for forager recruitment, worker losses and overall worker productivity. Moreover, we provide evidence that combinatorial exposure to pesticides increases the propensity of colonies to fail.

  20. Colony Level Prevalence and Intensity of Nosema ceranae in Honey Bees (Apis mellifera L.).

    Science.gov (United States)

    Jack, Cameron J; Lucas, Hannah M; Webster, Thomas C; Sagili, Ramesh R

    Nosema ceranae is a widely prevalent microsporidian parasite in the western honey bee. There is considerable uncertainty regarding infection dynamics of this important pathogen in honey bee colonies. Understanding the infection dynamics at the colony level may aid in development of a reliable sampling protocol for N. ceranae diagnosis, and provide insights into efficient treatment strategies. The primary objective of this study was to characterize the prevalence (proportion of the sampled bees found infected) and intensity (number of spores per bee) of N. ceranae infection in bees from various age cohorts in a colony. We examined N. ceranae infection in both overwintered colonies that were naturally infected with N. ceranae and in quadruple cohort nucleus colonies that were established and artificially inoculated with N. ceranae. We also examined and quantified effects of N. ceranae infection on hypopharyngeal gland protein content and gut pH. There was no correlation between the prevalence and intensity of N. ceranae infection in composite samples (pooled bee samples used for analysis). Our results indicated that the prevalence and intensity of N. ceranae infection is significantly influenced by honey bee age. The N. ceranae infection prevalence values from composite samples of background bees (unmarked bees collected from four different locations in a colony) were not significantly different from those pertaining to marked-bee age cohorts specific to each sampling date. The foraging-aged bees had a higher prevalence of N. ceranae infection when compared to nurse-aged bees. N. ceranae did not have a significant effect on hypopharyngeal gland protein content. Further, there was no significant difference in mean gut pH of N. ceranae infected bees and non-infected bees. This study provides comprehensive insights into N. ceranae infection dynamics at the colony level, and also demonstrates the effects of N. ceranae infection on hypopharyngeal gland protein content and

  1. Genetic diversity confers colony-level benefits due to individual immunity.

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    Simone-Finstrom, Michael; Walz, Megan; Tarpy, David R

    2016-03-01

    Several costs and benefits arise as a consequence of eusociality and group-living. With increasing group size, spread of disease among nest-mates poses selective pressure on both individual immunity and group-level mechanisms of disease resistance (social immunity). Another factor known to influence colony-level expression of disease is intracolony genetic diversity, which in honeybees (Apis mellifera) is a direct function of the number of mates of the queen. Colonies headed by queens with higher mating numbers have less variable infections of decreased intensity, though the underlying mechanisms remain unclear. By pathogen-challenging larvae in vitro, we decoupled larval immune response from mechanisms of social immunity. Our results show that baseline immunity and degree of immune response do not vary with genetic diversity. However, intracolony variance in antimicrobial peptide production after pathogen challenge decreases with increasing genetic diversity. This reduction in variability of the larval immune response could drive the mitigation of disease observed in genetically diverse colonies. © 2016 The Author(s).

  2. Colony-level assessment of Brucella and Leptospira in the Guadalupe fur seal, Isla Guadalupe, Mexico.

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    Ziehl-Quirós, E Carolina; García-Aguilar, María C; Mellink, Eric

    2017-01-24

    The relatively small population size and restricted distribution of the Guadalupe fur seal Arctocephalus townsendi could make it highly vulnerable to infectious diseases. We performed a colony-level assessment in this species of the prevalence and presence of Brucella spp. and Leptospira spp., pathogenic bacteria that have been reported in several pinniped species worldwide. Forty-six serum samples were collected in 2014 from pups at Isla Guadalupe, the only place where the species effectively reproduces. Samples were tested for Brucella using 3 consecutive serological tests, and for Leptospira using the microscopic agglutination test. For each bacterium, a Bayesian approach was used to estimate prevalence to exposure, and an epidemiological model was used to test the null hypothesis that the bacterium was present in the colony. No serum sample tested positive for Brucella, and the statistical analyses concluded that the colony was bacterium-free with a 96.3% confidence level. However, a Brucella surveillance program would be highly recommendable. Twelve samples were positive (titers 1:50) to 1 or more serovars of Leptospira. The prevalence was calculated at 27.1% (95% credible interval: 15.6-40.3%), and the posterior analyses indicated that the colony was not Leptospira-free with a 100% confidence level. Serovars Icterohaemorrhagiae, Canicola, and Bratislava were detected, but only further research can unveil whether they affect the fur seal population.

  3. The Macronutrients, Appetite, and Energy Intake.

    Science.gov (United States)

    Carreiro, Alicia L; Dhillon, Jaapna; Gordon, Susannah; Higgins, Kelly A; Jacobs, Ashley G; McArthur, Breanna M; Redan, Benjamin W; Rivera, Rebecca L; Schmidt, Leigh R; Mattes, Richard D

    2016-07-17

    Each of the macronutrients-carbohydrate, protein, and fat-has a unique set of properties that influences health, but all are a source of energy. The optimal balance of their contribution to the diet has been a long-standing matter of debate. Over the past half century, thinking has progressed regarding the mechanisms by which each macronutrient may contribute to energy balance. At the beginning of this period, metabolic signals that initiated eating events (i.e., determined eating frequency) were emphasized. This was followed by an orientation to gut endocrine signals that purportedly modulate the size of eating events (i.e., determined portion size). Most recently, research attention has been directed to the brain, where the reward signals elicited by the macronutrients are viewed as potentially problematic (e.g., contribute to disordered eating). At this point, the predictive power of the macronutrients for energy intake remains limited.

  4. Colony-level behavioral variation correlates with differences in expression of the foraging gene in red imported fire ants.

    Science.gov (United States)

    Bockoven, Alison A; Coates, Craig J; Eubanks, Micky D

    2017-09-13

    Among social insects, colony-level variation is likely to be widespread and have significant ecological consequences. Very few studies, however, have documented how genetic factors relate to behavior at the colony level. Differences in expression of the foraging gene have been associated with differences in foraging and activity of a wide variety of organisms. We quantified expression of the red imported fire ant foraging gene (sifor) in workers from 21 colonies collected across the natural range of Texas fire ant populations, but maintained under standardized, environmentally controlled conditions. Colonies varied significantly in their behavior. The most active colonies had up to 10 times more active foragers than the least active colony and more than 16 times as many workers outside the nest. Expression differences among colonies correlated with this colony-level behavioral variation. Colonies with higher sifor expression in foragers had, on average, significantly higher foraging activity, exploratory activity, and recruitment to nectar than colonies with lower expression. Expression of sifor was also strongly correlated with worker task (foraging versus working in the interior of the nest). These results provide insight into the genetic and physiological processes underlying collective differences in social behavior. Quantifying variation in expression of the foraging gene may provide an important tool for understanding and predicting the ecological consequences of colony-level behavioral variation. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  5. Food reinforcement, energy intake, and macronutrient choice.

    Science.gov (United States)

    Epstein, Leonard H; Carr, Katelyn A; Lin, Henry; Fletcher, Kelly D

    2011-07-01

    Food is a powerful reinforcer that motivates people to eat. The relative reinforcing value of food (RRV(food)) is associated with obesity and energy intake and interacts with impulsivity to predict energy intake. How RRV(food) is related to macronutrient choice in ad libitum eating tasks in humans has not been studied; however, animal research suggests that sugar or simple carbohydrates may be a determinant of reward value in food. This study assessed which macronutrients are associated with food reinforcement. Two hundred seventy-three adults with various body mass indexes were assessed for RRV(food), the relative reinforcing value of reading, food hedonics, energy intake in an ad libitum taste test, and usual energy intake derived from repeated 24-h dietary recalls. Multiple regression was used to assess the relation between predictors of total energy and energy associated with macronutrient intake after control for age, sex, income, education, minority status, and other macronutrient intakes. The results showed that the relative proportion of responding for food compared with reading (RRV(prop)) was positively related to body mass index, laboratory-measured energy intake, and usual energy intake. In addition, RRV(prop) was a predictor of sugar intake but not of total carbohydrate, fat, or protein intake. These results are consistent with basic animal research showing that sugar is related to food reward and with the hypothesis that food reward processes are more strongly related to eating than are food hedonics. This trial was registered at clinicaltrials.gov as NCT00962117.

  6. Negative Correlation between Individual-Insect-Level Virulence and Colony-Level Virulence of Paenibacillus larvae, the Etiological Agent of American Foulbrood of Honeybees▿

    Science.gov (United States)

    Rauch, Sandra; Ashiralieva, Ainura; Hedtke, Kati; Genersch, Elke

    2009-01-01

    Paenibacillus larvae is the etiological agent of American foulbrood (AFB) in honeybees. Recently, different genotypes of P. larvae (ERIC I to ERIC IV) were defined, and it was shown that these genotypes differ inter alia in their virulence on the larval level. On the colony level, bees mitigate AFB through the hygienic behavior of nurse bees. Therefore, we investigated how the hygienic behavior shapes P. larvae virulence on the colony level. Our results indicate that P. larvae virulence on the larval level and that on the colony level are negatively correlated. PMID:19304833

  7. Intraspecific Variation among Social Insect Colonies: Persistent Regional and Colony-Level Differences in Fire Ant Foraging Behavior.

    Directory of Open Access Journals (Sweden)

    Alison A Bockoven

    Full Text Available Individuals vary within a species in many ecologically important ways, but the causes and consequences of such variation are often poorly understood. Foraging behavior is among the most profitable and risky activities in which organisms engage and is expected to be under strong selection. Among social insects there is evidence that within-colony variation in traits such as foraging behavior can increase colony fitness, but variation between colonies and the potential consequences of such variation are poorly documented. In this study, we tested natural populations of the red imported fire ant, Solenopsis invicta, for the existence of colony and regional variation in foraging behavior and tested the persistence of this variation over time and across foraging habitats. We also reared single-lineage colonies in standardized environments to explore the contribution of colony lineage. Fire ants from natural populations exhibited significant and persistent colony and regional-level variation in foraging behaviors such as extra-nest activity, exploration, and discovery of and recruitment to resources. Moreover, colony-level variation in extra-nest activity was significantly correlated with colony growth, suggesting that this variation has fitness consequences. Lineage of the colony had a significant effect on extra-nest activity and exploratory activity and explained approximately half of the variation observed in foraging behaviors, suggesting a heritable component to colony-level variation in behavior.

  8. Intraspecific Variation among Social Insect Colonies: Persistent Regional and Colony-Level Differences in Fire Ant Foraging Behavior.

    Science.gov (United States)

    Bockoven, Alison A; Wilder, Shawn M; Eubanks, Micky D

    2015-01-01

    Individuals vary within a species in many ecologically important ways, but the causes and consequences of such variation are often poorly understood. Foraging behavior is among the most profitable and risky activities in which organisms engage and is expected to be under strong selection. Among social insects there is evidence that within-colony variation in traits such as foraging behavior can increase colony fitness, but variation between colonies and the potential consequences of such variation are poorly documented. In this study, we tested natural populations of the red imported fire ant, Solenopsis invicta, for the existence of colony and regional variation in foraging behavior and tested the persistence of this variation over time and across foraging habitats. We also reared single-lineage colonies in standardized environments to explore the contribution of colony lineage. Fire ants from natural populations exhibited significant and persistent colony and regional-level variation in foraging behaviors such as extra-nest activity, exploration, and discovery of and recruitment to resources. Moreover, colony-level variation in extra-nest activity was significantly correlated with colony growth, suggesting that this variation has fitness consequences. Lineage of the colony had a significant effect on extra-nest activity and exploratory activity and explained approximately half of the variation observed in foraging behaviors, suggesting a heritable component to colony-level variation in behavior.

  9. Nosema spp. infection and its negative effects on honey bees (Apis mellifera iberiensis) at the colony level.

    Science.gov (United States)

    Botías, Cristina; Martín-Hernández, Raquel; Barrios, Laura; Meana, Aránzazu; Higes, Mariano

    2013-04-10

    Nosemosis caused by the microsporidia Nosema apis and Nosema ceranae are among the most common pathologies affecting adult honey bees. N. apis infection has been associated with a reduced lifespan of infected bees and increased winter mortality, and its negative impact on colony strength and productivity has been described in several studies. By contrast, when the effects of nosemosis type C, caused by N. ceranae infection, have been analysed at the colony level, these studies have largely focused on collapse as a response to infection without addressing the potential sub-clinical effects on colony strength and productivity. Given the spread and prevalence of N. ceranae worldwide, we set out here to characterize the sub-clinical and clinical signs of N. ceranae infection on colony strength and productivity. We evaluated the evolution of 50 honey bee colonies naturally infected by Nosema (mainly N. ceranae) over a one year period. Under our experimental conditions, N. ceranae infection was highly pathogenic for honey bee colonies, producing significant reductions in colony size, brood rearing and honey production. These deleterious effects at the colony level may affect beekeeping profitability and have serious consequences on pollination. Further research is necessary to identify possible treatments or beekeeping techniques that will limit the rapid spread of this dangerous emerging disease.

  10. Soil macronutrient sensing for precision agriculture.

    Science.gov (United States)

    Kim, Hak-Jin; Sudduth, Kenneth A; Hummel, John W

    2009-10-01

    Accurate measurements of soil macronutrients (i.e., nitrogen, phosphorus, and potassium) are needed for efficient agricultural production, including site-specific crop management (SSCM), where fertilizer nutrient application rates are adjusted spatially based on local requirements. Rapid, non-destructive quantification of soil properties, including nutrient levels, has been possible with optical diffuse reflectance sensing. Another approach, electrochemical sensing based on ion-selective electrodes or ion-selective field effect transistors, has been recognized as useful in real-time analysis because of its simplicity, portability, rapid response, and ability to directly measure the analyte with a wide range of sensitivity. Current sensor developments and related technologies that are applicable to the measurement of soil macronutrients for SSCM are comprehensively reviewed. Examples of optical and electrochemical sensors applied in soil analyses are given, while advantages and obstacles to their adoption are discussed. It is proposed that on-the-go vehicle-based sensing systems have potential for efficiently and rapidly characterizing variability of soil macronutrients within a field.

  11. Evaluating the Effect of Environmental Chemicals on Honey Bee Development from the Individual to Colony Level.

    Science.gov (United States)

    Ko, Chong-Yu; Chen, Yue-Wen; Nai, Yu-Shin

    2017-04-01

    The presence of pesticides in the beekeeping environment is one of the most serious problems that impacts the life of a honey bee. Pesticides can be brought back to the beehive after the bees have foraged on flowers that have been sprayed with pesticides. Pesticide contaminated food can be exchanged between workers which then feed larvae and therefore can potentially affect the development of honey bees. Thus, residual pesticides in the environment can become a chronic damaging factor to honey bee populations and gradually lead to colony collapse. In the presented protocol, honey bee feeding methods are described and applied to either an individual honey bee or to a colony. Here, the insect growth regulator (IGR) pyriproxyfen (PPN), which is widely used to control pest insects and is harmful to the development of honey bee larvae and pupae, is used as the pesticide. The presenting procedure can be applied to other potentially harmful chemicals or honeybee pathogens for further studies.

  12. Balancing macronutrient intake in a mammalian carnivore: disentangling the influences of flavour and nutrition

    Science.gov (United States)

    Hewson-Hughes, Adrian K.; Colyer, Alison; Simpson, Stephen J.; Raubenheimer, David

    2016-01-01

    There is a large body of research demonstrating that macronutrient balancing is a primary driver of foraging in herbivores and omnivores, and more recently, it has been shown to occur in carnivores. However, the extent to which macronutrient selection in carnivores may be influenced by organoleptic properties (e.g. flavour/aroma) remains unknown. Here, we explore the roles of nutritional and hedonic factors in food choice and macronutrient balancing in a mammalian carnivore, the domestic cat. Using the geometric framework, we determined the amounts and ratio of protein and fat intake in cats allowed to select from combinations of three foods that varied in protein : fat (P : F) composition (approx. 10 : 90, 40 : 60 and 70 : 30 on a per cent energy basis) to which flavours of different ‘attractiveness’ (fish, rabbit and orange) were added. In two studies, in which animal and plant protein sources were used, respectively, the ratio and amounts of protein and fat intake were very consistent across all groups regardless of flavour combination, indicating regulation of both protein and fat intake. Our results suggest that macronutrient balancing rather than hedonistic rewards based on organoleptic properties of food is a primary driver of longer-term food selection and intake in domestic cats. PMID:27429768

  13. The endocannabinoid system: directing eating behavior and macronutrient metabolism

    Directory of Open Access Journals (Sweden)

    Bruce Alan Watkins

    2015-01-01

    Full Text Available For many years, the brain has been the primary focus for research on eating behavior. More recently, the discovery of the endogenous endocannabinoids (EC and the endocannabinoid system (ECS, as well as the characterization of its actions on appetite and metabolism, has provided greater insight on the brain and food intake. The purpose of this review is to explain the actions of EC in the brain and other organs as well as their precursor polyunsaturated fatty acids (PUFA that are converted to these endogenous ligands. The binding of the EC to the cannabinoid receptors in the brain stimulates food intake, and the ECS participates in systemic macronutrient metabolism where the gastrointestinal system, liver, muscle, and adipose are involved. The EC are biosynthesized from two distinct families of dietary PUFA, namely the n-6 and n-3. Based on their biochemistry, these PUFA are well known to exert considerable physiological and health-promoting actions. However, little is known about how these different families of PUFA compete as precursor ligands of cannabinoid receptors to stimulate appetite or perhaps down-regulate the ECS to amend food intake and prevent or control obesity. The goal of this review is to assess the current available research on ECS and food intake, suggest research that may improve the complications associated with obesity and diabetes by dietary PUFA intervention, and further reveal mechanisms to elucidate the relationships between substrate for EC synthesis, ligand actions on receptors, and the physiological consequences of the ECS. Dietary PUFA are lifestyle factors that could potentially curb eating behavior, which may translate to changes in macronutrient metabolism, systemically and in muscle, benefiting health overall.

  14. The endocannabinoid system: directing eating behavior and macronutrient metabolism.

    Science.gov (United States)

    Watkins, Bruce A; Kim, Jeffrey

    2014-01-01

    For many years, the brain has been the primary focus for research on eating behavior. More recently, the discovery of the endocannabinoids (EC) and the endocannabinoid system (ECS), as well as the characterization of its actions on appetite and metabolism, has provided greater insight on the brain and food intake. The purpose of this review is to explain the actions of EC in the brain and other organs as well as their precursor polyunsaturated fatty acids (PUFA) that are converted to these endogenous ligands. The binding of the EC to the cannabinoid receptors in the brain stimulates food intake, and the ECS participates in systemic macronutrient metabolism where the gastrointestinal system, liver, muscle, and adipose are involved. The EC are biosynthesized from two distinct families of dietary PUFA, namely the n-6 and n-3. Based on their biochemistry, these PUFA are well known to exert considerable physiological and health-promoting actions. However, little is known about how these different families of PUFA compete as precursor ligands of cannabinoid receptors to stimulate appetite or perhaps down-regulate the ECS to amend food intake and prevent or control obesity. The goal of this review is to assess the current available research on ECS and food intake, suggest research that may improve the complications associated with obesity and diabetes by dietary PUFA intervention, and further reveal mechanisms to elucidate the relationships between substrate for EC synthesis, ligand actions on receptors, and the physiological consequences of the ECS. Dietary PUFA are lifestyle factors that could potentially curb eating behavior, which may translate to changes in macronutrient metabolism, systemically and in muscle, benefiting health overall.

  15. Water Flow Affects Zooplankton Feeding by the Scleractinian Coral Galaxea fascicularis on a Polyp and Colony Level

    Directory of Open Access Journals (Sweden)

    Tim Wijgerde

    2012-01-01

    Full Text Available Several factors may affect heterotrophic feeding of benthic marine invertebrates, including water flow rate and polyp context (i.e., the presence of neighbouring polyps. We tested the interactive effects of water flow rate and polyp context on zooplankton feeding by the scleractinian coral Galaxea fascicularis. Single polyps and colonies were incubated in a flow cell for 30 minutes with an ambient Artemia nauplii concentration of 10,000 L−1 and water flow rates ranging from 1.25 to 40 cm s−1. Water flow rate and polyp context showed significant main and interactive effects on feeding rates of G. fascicularis polyps. More specifically, feeding rates were optimal at flow rates of 1.25 cm s−1 for single polyps and 5 to 10 cm s−1 for polyps inhabiting colonies. The presence of epizoic acoelomorph flatworms may have negatively affected the observed feeding rates, especially at high flow. Our results demonstrate that water flow affects coral feeding and thus heterotrophic nutrient input at both a polyp and colony level. These findings are of relevance to our understanding of how biotic and abiotic factors interact on coral heterotrophy and may serve to optimise coral aquaculture.

  16. Relationship between Serum Leptin, Ghrelin and Dietary Macronutrients in Women with Polycystic Ovary Syndrome

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    Bahram Pourghassem Gargari

    2015-10-01

    Full Text Available Background: Polycystic ovary syndrome (PCOS is the most common endocrinopathy in women. It may involve an impairment in physiologic regulation of leptin and ghrelin. There is limited, controversial data on the relation of dietary components with leptin and ghrelin in PCOS, so the current study has been conducted to explore the effects of different macronutrients on serum levels of leptin and ghrelin in PCOS and healthy subjects. Materials and Methods: In this case-control study, we randomly choose 30 PCOS patients and 30 healthy age and body mass index (BMI matched controls. Intake of macronutrients [protein, total fat, saturated, monounsaturated and polyunsaturated fatty acids (PUFA, carbohydrate, dietary fiber] and energy were assessed using 3-day, 24-hour food recall and food frequency questionnaires (FFQ. Fasting hormonal status was measured for each participant. Results: PCOS women had higher levels of serum leptin, insulin, testosterone, and luteinizing hormone (LH, whereas sex hormone-binding globulin (SHBG was lower compared to healthy women. There was no significant difference in mean ghrelin concentrations between the groups. Among PCOS women, independent of BMI and total energy intake, we observed an inverse association between leptin concentration and total dietary fat (β=-0.16, P<0.05 and saturated fatty acid (SFA intake (β=-0.58, P<0.05. This relationship was not seen in the healthy subjects. There was no significant association between ghrelin and macronutrients in PCOS and healthy participants. Conclusion: Certain habitual dietary components such as fat and SFA may decrease serum leptin, whereas ghrelin is not influenced by these in PCOS women. More studies are needed to better clarify the effects of dietary macronutrients on serum leptin and ghrelin.

  17. Long-term macronutrient stoichiometry of UK ombrotrophic peatlands

    Science.gov (United States)

    Schillereff, Daniel; Boyle, John; Toberman, Hannah; Adams, Jessica; Tipping, Ed

    2016-04-01

    Ombrotrophic peatlands across northern latitudes represent a globally-important store for carbon (C), nitrogen (N) and phosphorus (P) through the Holocene. A key characteristic of ombrotrophic bogs is that N, P and other elements vital to their biogeochemical functioning are almost exclusively supplied by hydrological and biological inputs from the atmosphere. While different mechanisms regulating the atmospheric supply of N and P and their limiting effects on bog productivity have been widely studied, limited attention has been paid to the long-term patterns of, and controls on, macronutrient accumulation, cycling and stoichiometry in ombrotrophic peatlands. Indeed there is a dearth of C, N and P stoichiometric data from the UK despite decades of peatland research. Using data from 15 sites, we report the first estimates of millennial-scale macronutrient concentrations and accumulation rates in UK ombrotrophic peats. Carbon, nitrogen and phosphorus concentrations were measured on cores from five ombrotrophic blanket mires, spanning 4000-10000 years to present, and integrated with existing nutrient profiles from ten Scottish sites. Long-term C, N and P concentrations for the UK are 55.1, 1.55 and 0.037 wt%, similar to the few existing northern and tropical comparable sites worldwide. The uppermost peat (0 - 0.2 m) is more enriched in P and N (51.0, 1.86, and 0.070 wt%), while the deeper peat (0.5 - 1.25 m) is more depleted (56.6, 1.39, and 0.028 wt%). Long-term average (whole core) accumulation rates of carbon, nitrogen and phosphorus are 25.3±2.2 gC m-2 yr-1, 0.70±0.09 gN m-2 yr-1 and 0.018±0.004 gP m-2 yr-1, again similar to values reported elsewhere in the world. A number of significant findings can be drawn from our results: i) N and P concentrations in ombrotrophic peat are strongly associated, such that a regression model of N concentration on P concentration and mean annual precipitation, based on global meta data for surface peat samples, can explain 54

  18. [Macronutrients, food intake and body weight; the role of fat].

    Science.gov (United States)

    Alcalá-Bejarano Carrillo, Jesús; Yago Torregrosa, Maria Dolores; Mañas Almendros, Mariano; López Millán, María Belén; Martínez Burgos, María Alba; Martínez de Victoria Muñoz, Emilio

    2014-11-27

    "Globesity" is the term that the World Health Organization (WHO) employs to define the growth of obesity in the world from the last 40 years which started in the developed countries and has been inevitably propagated to the developing ones. Governments and international organizations are aware of the problem and they are trying to implement measures to fight it. To analyze the current evidence in terms of studies about the relationship between macronutrients (especially fat and lipid release systems) and the secretion of gastrointestinal peptides that are involved with satiety and satiation. The search was conducted in Medline (via Pubmed) using different combinations of MeSH terms and in the database LILACs using "DeCS". A selection of another articles relevant to the review topic was also examined. At present, there are several laboratories and industries developing novel bioactive ingredients aimed at the regulation of food intake, with emphasis on those related with fat intake and the different ways in which fat can be technologically processed in order to create structures able to enhance satiety and/ or diminish hunger. These ingredients will be the future of functional foods focused on the prevention of weight gain and the support of other strategies against obesity (dietary, behavioral, etc…). Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  19. The Calculator of Anti-Alzheimer’s Diet. Macronutrients

    Science.gov (United States)

    Studnicki, Marcin; Woźniak, Grażyna; Stępkowski, Dariusz

    2016-01-01

    The opinions about optimal proportions of macronutrients in a healthy diet have changed significantly over the last century. At the same time nutritional sciences failed to provide strong evidence backing up any of the variety of views on macronutrient proportions. Herein we present an idea how these proportions can be calculated to find an optimal balance of macronutrients with respect to prevention of Alzheimer’s Disease (AD) and dementia. These calculations are based on our published observation that per capita personal income (PCPI) in the USA correlates with age-adjusted death rates for AD (AADR). We have previously reported that PCPI through the period 1925–2005 correlated with AADR in 2005 in a remarkable, statistically significant oscillatory manner, as shown by changes in the correlation coefficient R (Roriginal). A question thus arises what caused the oscillatory behavior of Roriginal? What historical events in the life of 2005 AD victims had shaped their future with AD? Looking for the answers we found that, considering changes in the per capita availability of macronutrients in the USA in the period 1929–2005, we can mathematically explain the variability of Roriginal for each quarter of a human life. On the basis of multiple regression of Roriginal with regard to the availability of three macronutrients: carbohydrates, total fat, and protein, with or without alcohol, we propose seven equations (referred to as “the calculator” throughout the text) which allow calculating optimal changes in the proportions of macronutrients to reduce the risk of AD for each age group: youth, early middle age, late middle age and late age. The results obtained with the use of “the calculator” are grouped in a table (Table 4) of macronutrient proportions optimal for reducing the risk of AD in each age group through minimizing Rpredicted−i.e., minimizing the strength of correlation between PCPI and future AADR. PMID:27992612

  20. The Consistency in Macronutrient Oxidation and the Role for Epinephrine in the Response to Fasting and Overfeeding.

    Science.gov (United States)

    Vinales, Karyne Lima; Schlögl, Mathias; Piaggi, Paolo; Hohenadel, Maximilian; Graham, Alexis; Bonfiglio, Susan; Krakoff, Jonathan; Thearle, Marie S

    2017-01-01

    In humans, dietary vs intraindividual determinants of macronutrient oxidation preference and the role of the sympathetic nervous system (SNS) during short-term overfeeding and fasting are unclear. To understand the influence on metabolic changes of diet and SNS during 24 hours of overfeeding. While residing on a clinical research unit, 64 participants with normal glucose regulation were assessed during energy balance, fasting, and four 24-hour overfeeding diets, given in random order. The overfeeding diets contained 200% of energy requirements and varied macronutrient proportions: (1) standard (50% carbohydrate, 20% protein, and 30% fat); (2) 75% carbohydrate; (3) 60% fat; and (4) 3% protein. Twenty-four-hour energy expenditure (EE) and macronutrient oxidation rates were measured in an indirect calorimeter during the dietary interventions, with concomitant measurement of urinary catecholamines and free cortisol. EE decreased with fasting (-7.7% ± 4.8%; P fasting and overfeeding diets (Δ = 2.25 ± 2.9 µg/24h; P fasting, higher urinary epinephrine concentrations correlated with smaller reductions in EE (ρ = 0.34; P = 0.01). Independent from dietary macronutrient proportions, there is a strong individual contribution to fuel preference that remains consistent across diets. Higher urinary epinephrine levels may reflect the importance of epinephrine in maintaining EE during fasting.

  1. Reguladores de crescimento vegetal na concentração de macronutrientes em videira Itália Plant growth regulators on macronutrients in Itália grapes

    Directory of Open Access Journals (Sweden)

    Teresinha Costa Silveira de Albuquerque

    2008-01-01

    Full Text Available Em clima tropical semi-árido, o uso de reguladores vegetais em fruteiras permite o manejo do crescimento vegetativo, tão necessário ao escalonamento da produção e ao aumento da fertilidade das gemas. Estas substâncias influenciam vários fenômenos fisiológicos relacionados com a absorção mineral, como a condutância de membrana e utilização metabólica de íons. O objetivo deste trabalho foi avaliar o crescimento vegetativo, produção de matéria seca dos ramos, concentração e quantidade acumulada de N, P, K, Ca e Mg nos ramos e nos pecíolos e produção de panículas florais em resposta ao uso de reguladores vegetais, em plantas de videira da cultivar Itália. No experimento foram avaliados três ciclos vegetativos e cinco tratamentos (controle, chlormequat - 1500 mg L-1; daminozide - 3000 mg L-1; uniconazole - 30 mg L-1 e cloreto de mepiquat - 300 mg L-1, aplicados nas plantas em pulverizações aos 35 e 70 dias após a poda. Com o chlormequat e o uniconazole ocorreu efeito cumulativo nas plantas, quando aplicados em ciclos sucessivos da cultura, favorecendo o acúmulo de nutrientes e a diferenciação de gemas férteis em comparação com as plantas controle das videiras 'Itália'. Embora o daminozide tenha inibido significativamente o crescimento das plantas, não resultou em maior acúmulo de nutrientes e emissão de panículas florais nas plantas tratadas.In semi-arid tropical climate, the use of plant growth regulators in fruit trees allows the vegetative growth control, so necessary to the assignment of the production and the increase of the fertility of the buds. These substances influence several physiological processes related to the mineral absorption, for example: membrane condutance and metabolic use of ions. The objective of this work was to evaluate vegetative growth, stem dry mater, N, P, K, Ca and Mg content in the stem and petiole and panicle production in response to plant growth regulators in grape "It

  2. Macronutrient considerations for the sport of bodybuilding.

    Science.gov (United States)

    Lambert, Charles P; Frank, Laura L; Evans, William J

    2004-01-01

    Participants in the sport of bodybuilding are judged by appearance rather than performance. In this respect, increased muscle size and definition are critical elements of success. The purpose of this review is to evaluate the literature and provide recommendations regarding macronutrient intake during both 'off-season' and 'pre-contest' phases. Body builders attempt to increase muscle mass during the off-season (no competitive events), which may be the great majority of the year. During the off-season, it is advantageous for the bodybuilder to be in positive energy balance so that extra energy is available for muscle anabolism. Additionally, during the off-season, adequate protein must be available to provide amino acids for protein synthesis. For 6-12 weeks prior to competition, body builders attempt to retain muscle mass and reduce body fat to very low levels. During the pre-contest phase, the bodybuilder should be in negative energy balance so that body fat can be oxidised. Furthermore, during the pre-contest phase, protein intake must be adequate to maintain muscle mass. There is evidence that a relatively high protein intake (approximately 30% of energy intake) will reduce lean mass loss relative to a lower protein intake (approximately 15% of energy intake) during energy restriction. The higher protein intake will also provide a relatively large thermic effect that may aid in reducing body fat. In both the off-season and pre-contest phases, adequate dietary carbohydrate should be ingested (55-60% of total energy intake) so that training intensity can be maintained. Excess dietary saturated fat can exacerbate coronary artery disease; however, low-fat diets result in a reduction in circulating testosterone. Thus, we suggest dietary fats comprise 15-20% of the body builders' off-season and pre-contest diets. Consumption of protein/amino acids and carbohydrate immediately before and after training sessions may augment protein synthesis, muscle glycogen

  3. Macronutrient replacement options for saturated fat: effects on cardiovascular health.

    Science.gov (United States)

    Flock, Michael R; Fleming, Jennifer A; Kris-Etherton, Penny M

    2014-02-01

    The purpose of this review is to discuss macronutrient replacement options for saturated fatty acids (SFAs) to optimize cardiovascular disease (CVD) risk reduction. Dietary recommendations advise decreasing SFAs. There is convincing evidence that replacing SFAs with unsaturated fat, both omega-6 and omega-3 polyunsaturated fatty acids, reduces CVD risk. Monounsaturated fatty acid substitution for SFAs also decreases CVD risk. Replacing SFAs with refined carbohydrate does little to alter CVD risk, whereas whole-grain CHO or lean protein substitutions beneficially affect CVD risk. Modifying the macronutrient composition of the diet by replacing SFAs with unsaturated fatty acids, as well as lean protein and carbohydrate from whole grains, all lower CVD risk. Research is needed to identify food sources of macronutrients that optimize CVD risk reduction.

  4. The Dietary Composition and Source of Macronutrients Determine Obesity Development

    DEFF Research Database (Denmark)

    Myrmel, Lene Secher

    The drastic worldwide increase in obesity during the last decades is accompanied with several different health disorders. The underlying mechanisms for this escalation is not clear, but certain alterations in the dietary macronutrient composition are suggested to be of importance. In addition...... fat and marine oils. To further investigate the importance of the macronutrient composition on obesity development, we have performed a series of mice experiments. Our results demonstrate that both the amount and source of macronutrients influence obesity development and related disorders. The anti-obesity...... fed salmon in a Western diet. However, a high dietary content of sucrose or other high glycemic index carbohydrates attenuate the anti-obesogenic effect of n-3 PUFAs. When casein is used as the protein source, a high protein:carbohydrate ratio prevents high fat diet induced obesity, this is observed...

  5. Neural responses to macronutrients: hedonic and homeostatic mechanisms.

    Science.gov (United States)

    Tulloch, Alastair J; Murray, Susan; Vaicekonyte, Regina; Avena, Nicole M

    2015-05-01

    The brain responds to macronutrients via intricate mechanisms. We review how the brain's neural systems implicated in homeostatic control of feeding and hedonic responses are influenced by the ingestion of specific types of food. We discuss how these neural systems are dysregulated in preclinical models of obesity. Findings from these studies can increase our understanding of overeating and, perhaps in some cases, the development of obesity. In addition, a greater understanding of the neural circuits affected by the consumption of specific macronutrients, and by obesity, might lead to new treatments and strategies for preventing unhealthy weight gain. Copyright © 2015 AGA Institute. Published by Elsevier Inc. All rights reserved.

  6. Ileal brake activation: macronutrient-specific effects on eating behavior?

    NARCIS (Netherlands)

    Avesaat, van M.; Troost, F.J.; Ripken, D.; Hendriks, H.F.; Masclee, A.A.M.

    2015-01-01

    Background:Activation of the ileal brake, by infusing lipid directly into the distal part of the small intestine, alters gastrointestinal (GI) motility and inhibits food intake. The ileal brake effect on eating behavior of the other macronutrients is currently unknown.Objective:The objective of this

  7. Validation testing of a soil macronutrient sensing system

    Science.gov (United States)

    Rapid on-site measurements of soil macronutrients (i.e., nitrogen, phosphorus, and potassium) are needed for site-specific crop management, where fertilizer nutrient application rates are adjusted spatially based on local requirements. This study reports on validation testing of a previously develop...

  8. Ileal brake activation: Macronutrient-specific effects on eating behavior?

    NARCIS (Netherlands)

    Avesaat, M. van; Troost, F.J.; Ripken, D.; Hendriks, H.F.; Aam, M.

    2015-01-01

    BACKGROUND: Activation of the ileal brake, by infusing lipid directly into the distal part of the small intestine, alters gastrointestinal (GI) motility and inhibits food intake. The ileal brake effect on eating behavior of the other macronutrients is currently unknown. OBJECTIVE: The objective of t

  9. Development of macronutrient composition of very preterm human milk

    NARCIS (Netherlands)

    Maas, YGH; Gerritsen, J; Hart, AAM; Hadders-Algra, M; Tamminga, P; Mirmiran, M; Spekreijse, H; Ruijters, J.M.

    1998-01-01

    The effects of gestational age at delivery (GA), postnatal age (PNA) and post-menstrual age (PMA=PNA+ GA, an indicator of autonomous developmental processes not affected by the moment of birth) on macronutrient composition of very preterm milk were studied. Total N, fat, lactose and carbohydrate con

  10. Ileal brake activation: macronutrient-specific effects on eating behavior?

    NARCIS (Netherlands)

    Avesaat, van M.; Troost, F.J.; Ripken, D.; Hendriks, H.F.; Masclee, A.A.M.

    2015-01-01

    Background:Activation of the ileal brake, by infusing lipid directly into the distal part of the small intestine, alters gastrointestinal (GI) motility and inhibits food intake. The ileal brake effect on eating behavior of the other macronutrients is currently unknown.Objective:The objective of this

  11. Characterization of the effects of macronutrient deficiencies in mangabeira seedlings

    Directory of Open Access Journals (Sweden)

    Layara Alexandre Bessa

    2012-12-01

    Full Text Available Knowledge of the mineral nutrition requirements of mangabeira (Hancornia speciosa Gomes is relatively scarce and rudimentary because there is a lack of consistent data concerning its nutritional demands at different developmental stages. The aim of this research was to characterize the visual symptoms of macronutrient deficiencies and to evaluate the effects of these deficiencies on the growth, the production of dry matter, and the leaf content of mangabeira. To achieve this goal, a greenhouse experiment was conducted at the Goiano Federal Institute (Instituto Federal Goiano in Rio Verde - GO, from January to June 2011 in which mangabeira plants were arranged in a random block design and grown in nutrient solutions. This experiment was replicated four times. The plants were treated with either a complete nutrient solution or a nutrient solution from which the individual macronutrient of interest (nitrogen (N, phosphorous (P, potassium (K, magnesium (Mg, calcium (Ca, or sulfur (S had been omitted. The omission of a macronutrient from the nutrient solution resulted in morphological alterations that were characteristic symptoms of the particular nutritional deficiency and caused decreases in growth and dry matter mass production. The accumulation of macronutrients displayed the following order in mangabeira leaves: N>K>Ca>P>S>Mg.

  12. ASSESSMENT OF MACRONUTRIENTS AND HEAVY METALS IN ...

    African Journals Online (AJOL)

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    against small pox, blood purification and also considered to be remedial for cancer [10, 11]. The ... The collected herb was dried in open at room temperature. .... regulation of an intimate rhythm and arterial pressure together with Ca [28].

  13. Dietary macronutrient recommendations for optimal recovery post ...

    African Journals Online (AJOL)

    Enrique

    the ratio of CHO to protein ingested, and the fat content of ... by both muscle contraction and insulin); glucose transport protein-4 (GLUT-4) ... insulin signalling and sensitivity, GLUT-4 content, and blood flow); ..... Regulation of glycogen resynthesis ... carbohydrate metabolism in relation to exercise intensity and duration. Am.

  14. Body composition and energy expenditure predict ad-libitum food and macronutrient intake in humans.

    Science.gov (United States)

    Weise, C M; Hohenadel, M G; Krakoff, J; Votruba, S B

    2014-02-01

    Obesity is the result of chronic positive energy balance. The mechanisms underlying the regulation of energy homeostasis and food intake are not understood. Despite large increases in fat mass (FM), recent evidence indicates that fat-free mass (FFM) rather than FM is positively associated with intake in humans. In 184 humans (73 females/111 males; age 34.5±8.8 years; percentage body fat: 31.6±8.1%), we investigated the relationship of FFM index (FFMI, kg m(-2)), FM index (FMI, kg m(-2)); and 24-h energy expenditure (EE, n=127) with ad-libitum food intake using a 3-day vending machine paradigm. Mean daily calories (CAL) and macronutrient intake (PRO, CHO, FAT) were determined and used to calculate the relative caloric contribution of each (%PRO, %CHO, %FAT) and percent of caloric intake over weight maintaining energy needs (%WMENs). FFMI was positively associated with CAL (Pintake (all PFood and macronutrient intake are predicted by FFMI and to a lesser degree by FMI. FFM and FM may have opposing effects on energy homeostasis.

  15. The Dietary Composition and Source of Macronutrients Determine Obesity Development

    DEFF Research Database (Denmark)

    Myrmel, Lene Secher

    to an elevation in energy intake, these alterations include increased consumption of refined carbohydrates and a relative decrease in protein consumption. The relative intake of dietary fat has not increased during the last decades, but the proportion of vegetable oils has increased at the expense of saturated...... fat and marine oils. To further investigate the importance of the macronutrient composition on obesity development, we have performed a series of mice experiments. Our results demonstrate that both the amount and source of macronutrients influence obesity development and related disorders. The anti...... fed salmon in a Western diet. However, a high dietary content of sucrose or other high glycemic index carbohydrates attenuate the anti-obesogenic effect of n-3 PUFAs. When casein is used as the protein source, a high protein:carbohydrate ratio prevents high fat diet induced obesity, this is observed...

  16. Individual responsiveness to shock and colony-level aggression in honey bees: evidence for a genetic component.

    Science.gov (United States)

    Avalos, Arian; Rodríguez-Cruz, Yoselyn; Giray, Tugrul

    2014-05-01

    The phenotype of the social group is related to phenotypes of individuals that form that society. We examined how honey bee colony aggressiveness relates to individual response of male drones and foraging workers. Although the natural focus in colony aggression has been on the worker caste, the sterile females engaged in colony maintenance and defense, males carry the same genes. We measured aggressiveness scores of colonies and examined components of individual aggressive behavior in workers and haploid sons of workers from the same colony. We describe for the first time, that males, although they have no stinger, do bend their abdomen (abdominal flexion) in a posture similar to stinging behavior of workers in response to electric shock. Individual worker sting response and movement rates in response to shock were significantly correlated with colony scores. In the case of drones, sons of workers from the same colonies, abdominal flexion significantly correlated but their movement rates did not correlate with colony aggressiveness. Furthermore, the number of workers responding at increasing levels of voltage exhibits a threshold-like response, whereas the drones respond in increasing proportion to shock. We conclude that there are common and caste-specific components to aggressive behavior in honey bees. We discuss implications of these results on social and behavioral regulation and genetics of aggressive response.

  17. From so simple a beginning: Enzymatic innovation in fungus-growing ants involved a transition from individual symbiont selection to colony-level selection

    DEFF Research Database (Denmark)

    de Fine Licht, Henrik Hjarvard; Schiøtt, Morten; Boomsma, Jacobus Jan

    the ants increased the share of fresh leaves in their forage. However, once in place, this novel enzyme function gave the entire mutualism a significant colony-level advantage, which allowed the leaf-cutting ants to evolve very large long-lived colonies and to become one of the most important...... of the partner species. Here we document such a sequence that was connected to a major evolutionary transition in the fungus-growing ants, when the ancestor of the derived leaf-cutting ants shifted from a diet of dry vegetative material to the almost exclusive use of freshly cut leaves. This shift generated...... visible adaptations in the host ants, such as increased worker dimorphism allowing large workers to cut fresh leaves, but comparative studies of the specific fungal adaptations that accompanied the transition have not been done. Here we report the first large comparative data set on enzymatic fungus...

  18. Macronutrients deficiency in Heliconia psittacorum x Heliconia spathocircinata 'Golden Torch'

    OpenAIRE

    Ana Cecília Ribeiro de Castro; Lilia Gomes Willadino; Vivian Loges; Mario Felipe Arruda de Castro; Fernando Antonio Souza de Aragão

    2015-01-01

    The objective of this study was to characterize nutritional deficiencies in Heliconia psittacorum x Heliconia spathocircinata 'Golden Torch', through growth indicators, symptomatology and macronutrients contents in leaves and underground plant part. The experiment was carried out in a greenhouse, with eight treatments comprising complete nutrition solution (N, P, K, Ca, Mg, S), solution with individual nutrient omission of N, P, K, Ca, Mg or S and solution lacking all nutrients. The symptoms ...

  19. Macronutrients Content and Energy Value of Fiber Rich Biscuits

    Directory of Open Access Journals (Sweden)

    Lovorka Vujić

    2007-09-01

    Full Text Available Cereals and cereal based products are an important source of energy, fibers and a range of macro- and micronutrients such as carbohydrates, proteins, minerals etc. Most of the evidences for health benefits of cereal foods are related to the fiber rich wholegrain foods and its role in reducing risk of degenerative chronic diseases, so-called Western diseases (constipation, diabetes, cardiovascular diseases, diverticulosis, obesity, and colon cancer. To evaluate fiber-rich cereal products as a functional food, nine types of biscuits based on whole grain wheat flour with enlarged share of dietary fibers were experimentally prepared. The goal of this study was to present the contents of main macronutrients, such as total proteins, carbohydrates and total fat in mentioned biscuits and to estimate contributions of each individual component to biscuit’s energy value in relation to new reference values. Our results show that regarding Dietary Reference Intakes (DRI given by the Food and Nutrition Board, USA (FNB 2005, examined biscuits can be considered as a good source of macronutrients and dietary fibers in nutrition. Consumption of those biscuits ensure relatively balanced intake of energy originated from main macronutrients. Being high in total dietary fibers (16.50 up to 46.77 g/1000 kcal that is considerably higher than recommended by Adequate Intake (AI for total dietary fibers based on 14 g/1000 kcal of required energy (DRI 2005, investigated biscuits can significantly contribute to the intake of those health enhancing components.

  20. Complex colony-level organization of the deep-sea siphonophore Bargmannia elongata (Cnidaria, Hydrozoa) is directionally asymmetric and arises by the subdivision of pro-buds.

    Science.gov (United States)

    Dunn, Casey W

    2005-12-01

    Siphonophores are free-swimming colonial hydrozoans (Cnidaria) composed of asexually produced multicellular zooids. These zooids, which are homologous to solitary animals, are functionally specialized and arranged in complex species-specific patterns. The coloniality of siphonophores provides an opportunity to study the major transitions in evolution that give rise to new levels of biological organization, but siphonophores are poorly known because they are fragile and live in the open ocean. The organization and development of the deep-sea siphonophore Bargmannia elongata is described here using specimens collected with a remotely operated underwater vehicle. Each bud gives rise to a precise, directionally asymmetric sequence of zooids through a stereotypical series of subdivisions, rather than to a single zooid as in most other hydrozoans. This initial description of development in a deep-sea siphonophore provides an example of how precise colony-level organization can arise, and illustrates that the morphological complexity of cnidarians is greater than is often assumed. Copyright 2005 Wiley-Liss, Inc.

  1. Macronutrients in watermelon plants fertilized with potassium and cattle manure

    Directory of Open Access Journals (Sweden)

    José A. M. do Nascimento

    Full Text Available ABSTRACT Potassium is the nutrient required in greatest quantity by watermelon, especially during the production phase. Therefore, the aim of this experiment was to evaluate the effect of potassium and cattle manure doses on the nutritional composition of ‘Crimson Sweet’ watermelon plants. The treatments were arranged in a randomized block design with three replicates and 21 plants per plot using a 3 × 5 + 1 factorial scheme, referring to three manure doses (0; 1,100 and 2,520 g hole-1, in order to increment the level of soil organic matter from 0.67 present in the soil to 3.0 and 6.0%, five potassium doses (0, 7.5, 15, 22.5 and 30 kg ha-1 in the form of potassium chloride and one additional treatment (without organic and mineral fertilization. At the beginning of fruiting, leaves were collected to evaluate the nutritional status of the plants in macronutrients. According to the results, cattle manure stimulates the absorption of macronutrients by watermelon; in soil with 3.0% of organic matter, the best results corresponded to the K2O dose of 15 kg ha-1 and, for 6.0%, between 11 and 13 kg ha-1.

  2. Functional food microstructures for macronutrient release and delivery.

    Science.gov (United States)

    Norton, J E; Gonzalez Espinosa, Y; Watson, R L; Spyropoulos, F; Norton, I T

    2015-03-01

    There is a need to understand the role of fat, protein and carbohydrate in human health, and also how foods containing and/or structured using these macronutrients can be designed so that they can have a positive impact on health. This may include a reduction in fat, salt or sugar, the protection and targeted release of micronutrients or active ingredients from/to particular parts of the digestive system, improvement of gastrointestinal health or satiety enhancing properties. Such foods can be designed with various macro- and microstructures that will impact on macronutrient release and delivery. These include simple and double emulsions, the use of Pickering particles and shells, nanoparticles, liposomes, gelled networks, fluid gels and gel particles, foams, self-assembled structures, and encapsulated systems. In order to design foods that deliver these benefits understanding of how these structures behave in the gastrointestinal tract is also required, which should involve utilising both in vitro and in vivo studies. This review aims to draw together research in these areas, by focusing on the current state of the art, but also exciting possibilities for future research and food development.

  3. Dietary Supplements and Health Aids - A Critical Evaluation Part 2 - Macronutrients and Fiber.

    Science.gov (United States)

    Dubick, Michael A.

    1983-01-01

    Part 1 of this evaluation of dietary supplements and health aids (SE 533 788) focused on various therapeutic claims made for vitamins and minerals. This part examines health-promoting claims made for selected macronutrients and fiber. Macronutrients examined include selected proteins, amino acids, enzymes, carbohydrates, and lipids. (JN)

  4. Macronutrient distribution over a period of 23 years in relation to energy intake and body fatness

    NARCIS (Netherlands)

    Koppes, L.L.J.; Boon, N.; Nooyens, A.C.J.; Mechelen, W. van; Saris, W.H.M.

    2009-01-01

    The distribution of the four macronutrients is associated with energy intake and body fatness according to short-term interventions. The present study involves macronutrient distribution in relation to energy intake and body fatness over a period of 23 years in individuals who have ad libitum access

  5. The reliability and validity of the Macronutrient and Taste Preference Ranking Task

    NARCIS (Netherlands)

    Bruijn, de Suzanne E.M.; Vries, de Yfke C.; Graaf, de Kees; Boesveldt, Sanne; Jager, Gerry

    2017-01-01

    Food preferences are for a large part determined by the macronutrient content and taste of foods, but may change depending on internal and external factors. Here, we discuss a newly developed food preference task, the Macronutrient and Taste Preference Ranking Task (MTPRT), in which participants

  6. Macronutrient distribution over a period of 23 years in relation to energy intake and body fatness

    NARCIS (Netherlands)

    Koppes, L.L.J.; Boon, N.; Nooyens, A.C.J.; Mechelen, W. van; Saris, W.H.M.

    2009-01-01

    The distribution of the four macronutrients is associated with energy intake and body fatness according to short-term interventions. The present study involves macronutrient distribution in relation to energy intake and body fatness over a period of 23 years in individuals who have ad libitum access

  7. Dietary Supplements and Health Aids - A Critical Evaluation Part 2 - Macronutrients and Fiber.

    Science.gov (United States)

    Dubick, Michael A.

    1983-01-01

    Part 1 of this evaluation of dietary supplements and health aids (SE 533 788) focused on various therapeutic claims made for vitamins and minerals. This part examines health-promoting claims made for selected macronutrients and fiber. Macronutrients examined include selected proteins, amino acids, enzymes, carbohydrates, and lipids. (JN)

  8. The Effects of Dietary Macronutrient Balance on Skin Structure in Aging Male and Female Mice

    Science.gov (United States)

    McMahon, Aisling C.; Ruohonen, Kari; Raubenheimer, David; Ballard, J. William O.; Le Couteur, David G.; Nicholls, Caroline; Li, Zhe; Maitz, Peter K. M.; Wang, Yiwei; Simpson, Stephen J.

    2016-01-01

    Nutrition influences skin structure; however, a systematic investigation into how energy and macronutrients (protein, carbohydrate and fat) affects the skin has yet to be conducted. We evaluated the associations between macronutrients, energy intake and skin structure in mice fed 25 experimental diets and a control diet for 15 months using the Geometric Framework, a novel method of nutritional analysis. Skin structure was associated with the ratio of dietary macronutrients eaten, not energy intake, and the nature of the effect differed between the sexes. In males, skin structure was primarily associated with protein intake, whereas in females carbohydrate intake was the primary correlate. In both sexes, the dermis and subcutaneous fat thicknesses were inversely proportional. Subcutaneous fat thickness varied positively with fat intake, due to enlarged adipocytes rather than increased adipocyte number. We therefore demonstrated clear interactions between skin structure and macronutrient intakes, with the associations being sex-specific and dependent on dietary macronutrient balance. PMID:27832138

  9. Global negative emissions capacity of ocean macronutrient fertilization

    Science.gov (United States)

    Harrison, Daniel P.

    2017-03-01

    In order to meet the goal of limiting global average temperature increase to less than 2 °C, it is increasingly apparent that negative emissions technologies of up to 10 Pg C yr‑1 will be needed before the end of the century. Recent research indicates that fertilization of the ocean with the macronutrients nitrogen and phosphorus where they limit primary production, may have sequestration advantages over fertilizing iron limited regions. Utilizing global datasets of oceanographic field measurements, and output from a high resolution global circulation model, the current study provides the first comprehensive assessment of the global potential for carbon sequestration from ocean macronutrient fertilization (OMF). Sufficient excess phosphate exists outside the iron limited surface ocean to support once-off sequestration of up to 3.6 Pg C by fertilization with nitrogen. Ongoing maximum capacity of nitrogen only fertilization is estimated at 0.7 ± 0.4 Pg C yr‑1. Sequestration capacity is expected to decrease from the upper toward the lower bound over time under continued intense fertilization. If N and P were used in combination the capacity is ultimately limited by societies willingness to utilize phosphate resources. Doubling current phosphate production would allow an additional 0.9 Pg C yr‑1 and consume 0.07% yr‑1 of known global resources. Therefore offsetting up to around 15% (1.5 Pg C yr‑1) of annual global CO2 emissions is assessed as being technically plausible. Environmental risks which to date have received little quantitative evaluation, could also limit the scale of implementation. These results reinforce the need to consider a multi-faceted approach to greenhouse gasses, including a reduction in emissions coupled with further research into negative emissions technologies.

  10. Waste compost effect on macronutrients in haplorthox soil

    Directory of Open Access Journals (Sweden)

    Valdinei Tadeu Paulino

    2013-12-01

    Full Text Available Composting is a controlled aerobic process to treat and stabilize organic wastes, transforming them into organic fertilizers. It is environmentally friendly (by treating polluting wastes and recycling nutrients and materials, sanitary (by breaking the cycle of diseases and eliminating vectors and socially beneficial (by generating jobs and improving crop yields. The use of compost from urban waste (the product obtained by composting the organic part of solid household wastes can improve soil fertility without harming the environment. This study aimed to evaluate the effect of levels of organic fertilizer (waste compost - WC on soil macronutrient contents. The experiment was performed at the Animal Nutrition and Pasture Center – Instituto de Zootecnia – Nova Odessa, SP, between January and June 2013, in a Haplorthox soil (pHCaCl2= 4.9, cultivated with piatagrass (Brachiaria brizantha, Stapf, without liming. The treatments involved five rates of WC application: 0, 2.0, 4.0, 6.0, 8.0 and 10.0 Mg ha-1, mixed with soil before sowing the grass. The experimental design was randomized blocks, with five replications, in pottery vessels (3.34 dm3. Soil samples were collected prior to the experiment (original soil and after cultivation of the grass (60 days after application. The samples were air dried and passed through sieves with 2 mm mesh and analyzed chemically. The macronutrients (P, S, in mg kg-1 and K, Ca and Mg mmolc kg-1 were quantified. The method to measure P, Ca, Mg and K was atomic emission spectrophotometry, after extraction with ion exchange resin, and the S concentration was measured by turbidimetry. The data were analyzed by the mixed procedure of SAS V. 9.2. The degrees of freedom related to the five rates (quantitative treatment were decomposed into orthogonal polynomials to obtain the best equation to fit the data. In the original soil, the concentrations of the macronutrients analyzed were considered low. The application of the WC

  11. Evaluation of macronutrient demand in calla lily (Zantedeschia aethiopica)

    DEFF Research Database (Denmark)

    Carneiro, Daniella N. M.; Lopes Coelho, Lívia; Paiva, Patrícia D. O.;

    2015-01-01

    Zantedeschia species are important plants in the flower market, but there is insufficient information available on nutrient absorption and accumulation for the various developmental stages of these plants. Therefore, we aimed to evaluate macronutrient accumulation in Zantedeschia aethiopica...... part (leaves, rhizomes, roots and flower stalks) and then calculated the dry mass accumulation and the nutrient contents. A randomized block study design was applied, with 4 replicates, totaling 48 plots. The aerial parts of the plants showed macronutrient content and accumulation in the sequences K......+>N>Ca2+>S>P>Mg and K>N>P>Ca>S>Mg, respectively, with the highest values being observed between 265 and 328 days after planting. The aerial parts showed greater accumulation of dry mass and macronutrients, whereas the flowers did not display significant macronutrient accumulation. The highest rates...

  12. Influence Of Species, Season, And Soil On Foliar Macronutrients In The Great Dismal Swamp

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Leaf macronutrient variation was studied in four plant communities in the Dismal Swamp of Virginia. Soils and species composition differed markedly between sites....

  13. Improvement of aquaponic performance through micro- and macro-nutrient addition.

    Science.gov (United States)

    Ru, Dongyun; Liu, Jikai; Hu, Zhen; Zou, Yina; Jiang, Liping; Cheng, Xiaodian; Lv, Zhenting

    2017-07-01

    Aquaponics is one of the "zero waste" industry in the twenty-first century, and is considered to be one of the major trends for the future development of agriculture. However, the low nitrogen utilization efficiency (NUE) restricted its widely application. To date, many attempts have been conducted to improve its NUE. In the present study, effect of micro- and macro-nutrient addition on performance of tilapia-pak choi aquaponics was investigated. Results showed that the addition of micro- and macro-nutrients improved the growth of plant directly and facilitated fish physiology indirectly, which subsequently increased NUE of aquaponics from 40.42 to 50.64%. In addition, remarkable lower total phosphorus concentration was obtained in aquaponics with micro- and macro-nutrient addition, which was attributed to the formation of struvite. Most of the added micro-nutrients were enriched in plant root, while macro-nutrients mainly existed in water. Moreover, no enrichment of micro- and macro-nutrients in aquaponic products (i.e., fish and plant leaves) was observed, indicating that it had no influence on food safety. The findings here reported manifest that appropriate addition of micro- and macro-nutrients to aquaponics is necessary, and would improve its economic feasibility.

  14. Interaction of plant phenols with food macronutrients: characterisation and nutritional-physiological consequences.

    Science.gov (United States)

    Zhang, Hao; Yu, Dandan; Sun, Jing; Liu, Xianting; Jiang, Lu; Guo, Huiyuan; Ren, Fazheng

    2014-06-01

    Polyphenols are dietary constituents of plants associated with health-promoting effects. In the human diet, polyphenols are generally consumed in foods along with macronutrients. Because the health benefits of polyphenols are critically determined by their bioavailability, the effect of interactions between plant phenols and food macronutrients is a very important topic. In the present review, we summarise current knowledge, with a special focus on the in vitro and in vivo effects of food macronutrients on the bioavailability and bioactivity of polyphenols. The mechanisms of interactions between polyphenols and food macronutrients are also discussed. The evidence collected in the present review suggests that when plant phenols are consumed along with food macronutrients, the bioavailability and bioactivity of polyphenols can be significantly affected. The protein-polyphenol complexes can significantly change the plasma kinetics profile but do not affect the absorption of polyphenols. Carbohydrates can enhance the absorption and extend the time needed to reach a maximal plasma concentration of polyphenols, and fats can enhance the absorption and change the absorption kinetics of polyphenols. Moreover, as highlighted in the present review, not only a nutrient alone but also certain synergisms between food macronutrients have a significant effect on the bioavailability and biological activity of polyphenols. The review emphasises the need for formulations that optimise the bioavailability and in vivo activities of polyphenols.

  15. Quality control analysis of imported fertilizers used in Ghana: the macronutrients perspective

    Directory of Open Access Journals (Sweden)

    Sheriff Enti-Brown

    2012-03-01

    Full Text Available The main objective of this environmental research was to validate specifications indicated by manufacturers on their fertilizer products. Selected fertilizers types were sampled from five major fertilizer importing companies in Ghana for macronutrient analysis to determine the fertilizer quality. Five analytical techniques including Instrumental Neutron Activation Analysis (INAA, flame photometry, Kjeldahl method for nitrogen analysis and UV-visible spectroscopy were employed to achieve this objective. Two reference materials (IAEA Soil-7 and SRM 1646a Estuarine Sediment were used to validate the quantitative method employed in the INAA. There was generally good agreements (98% and above between the measured values and the certified values for the primary macronutrients nitrogen, phosphorous and potassium (N, P and K. However, same could not be said for secondary macronutrients calcium, magnesium and sulphur (Ca, Mg and S. The secondary macronutrient values measured were compared to standard values from the Ministry of Food and Agriculture (MOFA in cases where they were not certified by the manufacturer. Most of the manufacturers' claims for primary macronutrients were valid. However, most of them fell short of the requirements for secondary macronutrient concentration. There is therefore the need for a good quality control system to undertake periodic quality monitoring of the chemical compositions of fertilizers imported into the country since they may directly or indirectly have impacts on the environment.

  16. Macronutrients deficiency in Heliconia psittacorum x Heliconia spathocircinata 'Golden Torch'

    Directory of Open Access Journals (Sweden)

    Ana Cecília Ribeiro de Castro

    Full Text Available The objective of this study was to characterize nutritional deficiencies in Heliconia psittacorum x Heliconia spathocircinata 'Golden Torch', through growth indicators, symptomatology and macronutrients contents in leaves and underground plant part. The experiment was carried out in a greenhouse, with eight treatments comprising complete nutrition solution (N, P, K, Ca, Mg, S, solution with individual nutrient omission of N, P, K, Ca, Mg or S and solution lacking all nutrients. The symptoms of nutrients deficiency appeared in the following occurrence order: N, K, P, Mg and S. Deficiency symptoms were: general chlorosis to - N omission; slight chlorosis to - P and - S; dark green leaves and necrosis to - K; marginal chlorosis and necrosis to - Mg. Calcium omission did not cause any visual symptom. Deficiencies in N and P affected more intensely shoot number, leaf dry mass production, total leaf number and leaf area. Among the evaluated leaves, there was a tendency of a highest decrease in the contents in the third leaf.

  17. Dietary sources of energy and macronutrient intakes among Flemish preschoolers.

    Science.gov (United States)

    De Keyzer, Willem; Lin, Yi; Vereecken, Carine; Maes, Lea; Van Oyen, Herman; Vanhauwaert, Erika; De Backer, Guy; De Henauw, Stefaan; Huybrechts, Inge

    2011-11-01

    This study aims to identify major food sources of energy and macronutrients among Flemish preschoolers as a basis for evaluating dietary guidelines. Three-day estimated diet records were collected from a representative sample of 696 Flemish preschoolers (2.5-6.5 years old; participation response rate: 50%). For 11 dietary constituents, the contribution of 57 food groups was computed by summing the amount provided by the food group for all individuals divided by the total intake of the respective nutrient for all individuals. Bread (12%), sweet snacks (12%), milk (6%), flavoured milk drinks (9%), and meat products (6%) were the top five energy contributors. Sweet snacks were among the top contributors to energy, total fat, all fatty acids, cholesterol, and complex and simple carbohydrates. Fruit juices and flavoured milk drinks are the main contributors to simple carbohydrates (respectively 14% and 18%). All principal food groups like water, bread and cereals, vegetables, fruit, milk and spreadable fats were under-consumed by more than 30% of the population, while the food groups that were over-consumed consisted only of low nutritious and high energy dense foods (sweet snacks, sugared drinks, fried potatoes, sauces and sweet spreads). From the major food sources and gaps in nutrient and food intakes, some recommendations to pursue the nutritional goals could be drawn: the intake of sweet snacks and sugar-rich drinks (incl. fruit juices) should be discouraged, while consumption of fruits, vegetables, water, bread and margarine on bread should be encouraged.

  18. Food price policy can favorably alter macronutrient intake in China.

    Science.gov (United States)

    Guo, X; Popkin, B M; Mroz, T A; Zhai, F

    1999-05-01

    The rapid change in diets, physical activity and body composition in low income countries has led to the coexistence of large pockets of undernutrition and overnutrition. Public health strategies for addressing this situation may be necessary, and price policy options are examined for China. Longitudinal dietary data collected in China in 1989-1993 on a sample of 5625 adults aged 20-45 y were examined. Three-day averages of food group consumption and nutrient intake were used in longitudinal statistical models to examine separately the effects of food prices on the decision to consume each food group and then the amount consumed. The effects of changes in six food prices on the consumption of each of six food groups, not just the food group whose price had changed, and on three macronutrients were estimated. The effects show large and significant price effects. If the joint effects of the nutrition transition are to be considered, then there are clear tradeoffs among which foods to tax and which to subsidize. Most important is the effect of prices in reducing fat intake of the rich but not adversely affecting protein intake for the poor. Increases in the prices of pork, eggs and edible oils are predicted to lower fat intake. Only increases in pork prices led to reduced protein intakes. This raises questions about earlier policy changes being implemented in China and provides insight into an important and controversial area for public health policy.

  19. Altered salience network connectivity predicts macronutrient intake after sleep deprivation.

    Science.gov (United States)

    Fang, Zhuo; Spaeth, Andrea M; Ma, Ning; Zhu, Senhua; Hu, Siyuan; Goel, Namni; Detre, John A; Dinges, David F; Rao, Hengyi

    2015-02-03

    Although insufficient sleep is a well-recognized risk factor for overeating and weight gain, the neural mechanisms underlying increased caloric (particularly fat) intake after sleep deprivation remain unclear. Here we used resting-state functional magnetic resonance imaging and examined brain connectivity changes associated with macronutrient intake after one night of total sleep deprivation (TSD). Compared to the day following baseline sleep, healthy adults consumed a greater percentage of calories from fat and a lower percentage of calories from carbohydrates during the day following TSD. Subjects also exhibited increased brain connectivity in the salience network from the dorsal anterior cingulate cortex (dACC) to bilateral putamen and bilateral anterior insula (aINS) after TSD. Moreover, dACC-putamen and dACC-aINS connectivity correlated with increased fat and decreased carbohydrate intake during the day following TSD, but not during the day following baseline sleep. These findings provide a potential neural mechanism by which sleep loss leads to increased fat intake.

  20. Macronutrient supplementation and food prices in HIV treatment.

    Science.gov (United States)

    Sztam, Kevin A; Fawzi, Wafaie W; Duggan, Christopher

    2010-01-01

    Infection caused by HIV and malnutrition have a complex interaction and often coexist geographically. Malnutrition has synergistic immune effects and HIV affects nutritional status. HIV care and treatment programs are compelled to confront this dual burden to optimize HIV outcomes. In this article, we review the published literature concerning intervention studies in adults and children and the effect of food prices on HIV treatment programs. While the evidence base is relatively incomplete for specific macronutrient interventions in the context of HIV treatment, it is clear that a new standard of care is needed, guided by experience, rationale, and existing data, in which malnourished patients may easily access nutritional therapies within HIV treatment. From this clinical foundation, we may both treat patients and evaluate novel therapies. Some HIV care and treatment programs provide food-based supplements; however, rising food costs and economic instability may jeopardize the success of these programs. HIV treatment programs may struggle to meet the needs of patients with potential increased rates of malnutrition and food insecurity in the setting of high food prices.

  1. Macronutrients mediate the functional relationship between Drosophila and Wolbachia.

    Science.gov (United States)

    Ponton, Fleur; Wilson, Kenneth; Holmes, Andrew; Raubenheimer, David; Robinson, Katie L; Simpson, Stephen J

    2015-02-07

    Wolbachia are maternally inherited bacterial endosymbionts that naturally infect a diverse array of arthropods. They are primarily known for their manipulation of host reproductive biology, and recently, infections with Wolbachia have been proposed as a new strategy for controlling insect vectors and subsequent human-transmissible diseases. Yet, Wolbachia abundance has been shown to vary greatly between individuals and the magnitude of the effects of infection on host life-history traits and protection against infection is correlated to within-host Wolbachia abundance. It is therefore essential to better understand the factors that modulate Wolbachia abundance and effects on host fitness. Nutrition is known to be one of the most important mediators of host-symbiont interactions. Here, we used nutritional geometry to quantify the role of macronutrients on insect-Wolbachia relationships in Drosophila melanogaster. Our results show fundamental interactions between diet composition, host diet selection, Wolbachia abundance and effects on host lifespan and fecundity. The results and methods described here open a new avenue in the study of insect-Wolbachia relationships and are of general interest to numerous research disciplines, ranging from nutrition and life-history theory to public health.

  2. Peripheral blood mononuclear cells as a source to detect markers of homeostatic alterations caused by the intake of diets with an unbalanced macronutrient composition.

    Science.gov (United States)

    Díaz-Rúa, Rubén; Keijer, Jaap; Caimari, Antoni; van Schothorst, Evert M; Palou, Andreu; Oliver, Paula

    2015-04-01

    Peripheral blood mononuclear cells (PBMCs) are accessible in humans, and their gene expression pattern was shown to reflect overall physiological response of the body to a specific stimulus, such as diet. We aimed to study the impact of sustained intake (4months) of diets with an unbalanced macronutrient proportion (rich in fat or protein) administered isocalorically to a balanced control diet, as physiological stressors on PBMC whole-genome gene expression in rats, to better understand the effects of these diets on metabolism and health and to identify biomarkers of nutritional imbalance. Dietary macronutrient composition (mainly increased protein content) altered PBMC gene expression, with genes involved in immune response being the most affected. Intake of a high-fat (HF) diet decreased the expression of genes related to antigen recognition/presentation, whereas the high-protein (HP) diet increased the expression of these genes and of genes involved in cytokine signaling and immune system maturation/activation. Key energy homeostasis genes (mainly related to lipid metabolism) were also affected, reflecting an adaptive response to the diets. Moreover, HF diet feeding impaired expression of genes involved in redox balance regulation. Finally, we identified a common gene expression signature of 7 genes whose expression changed in the same direction in response to the intake of both diets. These genes, individually or together, constitute a potential risk marker of diet macronutrient imbalance. In conclusion, we newly show that gene expression analysis in PBMCs allows for detection of diet-induced physiological deviations that distinguish from a diet with a proper and equilibrated macronutrient composition. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Macronutrient contributions of insects to the diets of hunter-gatherers: a geometric analysis.

    Science.gov (United States)

    Raubenheimer, David; Rothman, Jessica M; Pontzer, Herman; Simpson, Stephen J

    2014-06-01

    We present a geometric model for examining the macronutrient contributions of insects in the diets of pre-agricultural humans, and relate the findings to some contemporary societies that regularly eat insects. The model integrates published data on the macronutrient composition of insects and other foods in the diets of humans, recommended human macronutrient intakes, and estimated macronutrient intakes to examine the assumption that insects provided to pre-agricultural humans an invertebrate equivalent of vertebrate-derived meats, serving primarily as a source of protein. Our analysis suggests that insects vary more widely in their macronutrient content than is likely to be the case for most wild vertebrate meats, spanning a broad range of protein, fat and carbohydrate concentrations. Potentially, therefore, in terms of their proportional macronutrient composition, insects could serve as equivalents not only of wild meat, but of a range of other foods including some shellfish, nuts, pulses, vegetables and even fruits. Furthermore, humans might systematically manipulate the composition of edible insects to meet specific needs through pre-ingestive processing, such as cooking and selective removal of body parts. We present data suggesting that in modern societies for which protein is the more limiting macronutrient, pre-ingestive processing of edible insects might serve to concentrate protein. It is likely, however, that the dietary significance of insects was different for Paleolithic hunter-gatherers who were more limited in non-protein energy. Our conclusions are constrained by available data, but highlight the need for further studies, and suggest that our model provides an integrative framework for conceiving these studies. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Nutritional status of the cauliflower cultivar 'verona' grown with omission of out added macronutrients.

    Science.gov (United States)

    Bianco, Matheus Saraiva; Cecílio Filho, Arthur Bernardes; de Carvalho, Leonardo Bianco

    2015-01-01

    Knowledge of plant nutritional status allows an understanding of the physiological responses of plants to crop fertilization. A hydroponic experiment evaluated the symptoms of macronutrient deficiency in cauliflower 'Verona' and determined: a) the macronutrient contents of foliar tissues when visual symptoms were observed, b) macronutrients content of foliar and inflorescence tissues at harvest. The effect of nutrient deficiency on inflorescence mass was also evaluated. Nitrogen deficiency caused chlorosis followed by purple color in the old leaves, while P deficiency caused only chlorosis in old leaves. Chlorosis at the edge of old leaves progressing to the center of the leaves was observed with the omission of K, and after was observed necrosis in the chlorotic areas. Ca deficiency caused tip burn in new leaves, while Mg deficiency caused internerval chlorosis in old leaves. The omission of each macronutrient reduced inflorescence dry matter. This deleterious effect was larger for N, P, and K deficiencies, reducing inflorescence dry matter by 87, 49, and 42%, respectively. When the nutrient solutions without N, P, K, Ca, or Mg were supplied to cauliflower plants, the macronutrient contents at harvest were 8.8, 0.6, 3.5, 13.0, and 0.8 g kg-1 in the foliar tissues and 27.3, 2.2, 21.6, 1.1, and 0.7 g kg-1 in the inflorescence tissues, respectively.

  5. Long-term macronutrient stoichiometry of UK ombrotrophic peatlands.

    Science.gov (United States)

    Schillereff, Daniel N; Boyle, John F; Toberman, Hannah; Adams, Jessica L; Bryant, Charlotte L; Chiverrell, Richard C; Helliwell, Rachel C; Keenan, Patrick; Lilly, Allan; Tipping, Edward

    2016-12-01

    In this paper we report new data on peat carbon (C), nitrogen (N) and phosphorus (P) concentrations and accumulation rates for 15 sites in the UK. Concentrations of C, N and P measured in peat from five ombrotrophic blanket mires, spanning 4000-10,000years to present were combined with existing nutrient data from ten Scottish ombrotrophic peat bogs to provide the first UK perspective on millennial scale macronutrient concentrations in ombrotrophic peats. Long-term average C, N and P concentrations (0-1.25m) for the UK are 54.8, 1.56 and 0.039wt%, of similar magnitude to the few published comparable sites worldwide. The uppermost peat (0-0.2m) is enriched in P and N (51.0, 1.86, and 0.070wt%) relative to the deeper peat (0.5-1.25m, 56.3, 1.39, and 0.027wt%). Long-term average (whole core) accumulation rates of C, N and P are 25.3±2.2gCm(-2)year(-)(1) (mean±SE), 0.70±0.09gNm(-2)year(-1) and 0.018±0.004gPm(-2)year(-1), again similar to values reported elsewhere in the world. The two most significant findings are: 1) that a regression model of N concentration on P concentration and mean annual precipitation, based on global meta data for surface peat samples, can explain 54% of variance in N concentration in these UK peat profiles; and 2) budget calculations for the UK peat cores yield an estimate for long-term average N-fixation of 0.8gm(-2)year(-1). Our UK results, and comparison with others sites, corroborate published estimates of N storage in northern boreal peatlands through the Holocene as ranging between 8 and 15Pg N. However, the observed correlation of N% with both mean annual precipitation and P concentration allows a potential bias in global estimates that do not take this into account. The peat sampling data set has been deposited at the NERC Data Centre (Toberman et al., 2016).

  6. Central oxytocin and food intake: focus on macronutrient-driven reward

    Directory of Open Access Journals (Sweden)

    Anica eKlockars

    2015-04-01

    Full Text Available Centrally acting oxytocin (OT is known to terminate food consumption in response to excessive stomach distension, increase in salt loading and presence of toxins. Hypothalamic-hindbrain OT pathways facilitate these aspects of OT-induced hypophagia. However, recent discoveries have implicated OT in modifications of feeding via reward circuits: OT has been found to differentially affect consumption of individual macronutrients in choice and no-choice paradigms. In this mini-review, we focus on presenting and interpreting evidence that defines OT as a key component of mechanisms that reduce eating for pleasure and shape macronutrient preferences. We also provide remarks on challenges in integrating the knowledge on physiological and pathophysiological states in which both OT activity and macronutrient preferences are affected.

  7. Macronutrient Composition of Menu Offerings in Fast Food Restaurants in the U.S.

    Science.gov (United States)

    Jarlenski, Marian P; Wolfson, Julia A; Bleich, Sara N

    2016-10-01

    A high intake of fast food is associated with increased obesity risk. This study assessed recent changes in caloric content and macronutrient composition in large U.S. fast food restaurants. Data from the MenuStat project included 11,737 menu items in 37 fast food restaurants from 2012 to 2014. Generalized linear models were used to examine changes in the caloric content and corresponding changes in the macronutrient composition (non-sugar carbohydrates, sugar, unsaturated fat, saturated fat, and protein) of menu items over time. Additionally, macronutrient composition was compared in menu items newly introduced in 2013 and 2014, relative to 2012. Analyses, conducted in January 2016, controlled for restaurant and were stratified by menu categories. Overall, there was a 22-calorie reduction in food items from 2012 to 2014. Beverages had a 46-calorie increase, explained by an increase in calories from sugar (12 calories) and saturated fat (16 calories). Newly introduced main courses in 2014 had 59 calories fewer than those on 2012 menus, explained by a 54-calorie reduction in unsaturated fat, while other macronutrient content remained fairly constant. Newly introduced dessert items in 2014 had 90 calories more than those on 2012 menus, explained primarily by an increase of 57 calories of sugar. Overall, there were relatively minor changes in menu items' caloric and macronutrient composition. Although declines in caloric content among newly introduced fast food main courses may improve the public's caloric intake, it appears that the macronutrient composition of newly introduced items did not shift to a healthier profile. Copyright © 2016 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  8. Foods, macronutrients and fibre in the diet of blue sheep (Psuedois nayaur) in the Annapurna Conservation Area of Nepal.

    Science.gov (United States)

    Aryal, Achyut; Coogan, Sean C P; Ji, Weihong; Rothman, Jessica M; Raubenheimer, David

    2015-09-01

    Food resources are often critical regulating factors affecting individual fitness and population densities. In the Himalayan Mountains, Bharal "blue sheep" (Pseudois nayaur) are the main food resource for the endangered snow leopard (Panthera uncia), as well as being preyed upon by other predators. Blue sheep, however, may face a number of challenges including food resource competition with other wild and domestic ungulates, and hunting pressure. Here, we characterized the diet of blue sheep in the Annapurna Conservation Area (ACA) of Nepal and conducted proximate nutritional analysis on a limited number of plants identified as foods. Furthermore, we investigated the macronutrient and fiber balance of these plants using nutritional geometry which is a state-space approach to modeling multidimensional and interactive nutritional aspects of foraging. A total of 19 plant species/genera were identified in blue sheep pellets using microhistological analysis. On average, across seasons and regions of the study area, the two most frequently occurring plants in pellets were graminoids: Kobressia sp. and Carex spp. The macronutrient balance of Kobresia sp. was relatively high in carbohydrate and low in protein, while other plants in the diet were generally higher in protein and lipid content. Analysis of fiber balance showed that the two most consumed plants of blue sheep (i.e., Kobresia spp. and Carex spp.) contained the highest concentration of hemicellulose, which is likely digestible by blue sheep. The hemicellulose and lignin balance of plants ranged relatively widely, yet their cellulose contents showed less variation. Foraging by blue sheep may therefore be a balance between consuming highly digestible high-carbohydrate plants and plants less-digestible but higher in protein and/or lipid.

  9. Preterm Human Milk Macronutrient and Energy Composition: A Systematic Review and Meta-Analysis.

    Science.gov (United States)

    Mimouni, Francis B; Lubetzky, Ronit; Yochpaz, Sivan; Mandel, Dror

    2017-03-01

    This study is a systematic review of the macronutrient and energy composition of preterm human milk to enable the practicing neonatologist to make informed nutritional decisions in preterm infants. Meta-analyses were conducted in all the studies that reported total energy, true protein, fat, and lactose. Protein content decreased massively (by one-half) and significantly from day 1 to 3 at week 10 to 12. There was a significant linear increase in fat, lactose, and energy content during the same timeframe. Theoretic calculations on energy and macronutrient intake of preterm infants must be made according to a lactation time-specific manner. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake

    NARCIS (Netherlands)

    T. Tanaka (Toshiko); J.S. Ngwa; F.J.A. van Rooij (Frank); M.C. Zillikens (Carola); M.K. Wojczynski (Mary ); A.C. Frazier-Wood (Alexis); D.K. Houston (Denise); S. Kanoni (Stavroula); R.N. Lemaitre (Rozenn ); J. Luan; V. Mikkilä (Vera); F. Renström (Frida); E. Sonestedt (Emily); J.H. Zhao (Jing); A.Y. Chu (Audrey); L. Qi (Lu); D.I. Chasman (Daniel); M.C. De Oliveira Otto (Marcia); E.J. Dhurandhar (Emily); M.F. Feitosa (Mary Furlan); I. Johansson (Ingegerd); K-T. Khaw (Kay-Tee); K. Lohman (Kurt); A. Manichaikul (Ani); N.M. McKeown (Nicola ); D. Mozaffarian (Dariush); A.B. Singleton (Andrew); K. Stirrups (Kathy); J. Viikari (Jorma); Z. Ye (Zheng); S. Bandinelli (Stefania); I. Barroso (Inês); P. Deloukas (Panagiotis); N.G. Forouhi (Nita); A. Hofman (Albert); Y. Liu (Yongmei); L.-P. Lyytikäinen (Leo-Pekka); K.E. North (Kari); M. Dimitriou (Maria); G. Hallmans (Göran); M. Kähönen (Mika); C. Langenberg (Claudia); J.M. Ordovas (Jose); A.G. Uitterlinden (André); F.B. Hu (Frank); I.-P. Kalafati (Ioanna-Panagiota); O. Raitakari (Olli); O.H. Franco (Oscar); A. Johnson (Anthony); V. Emilsson (Valur); J.A. Schrack (Jennifer); R.D. Semba; D.S. Siscovick (David); D.K. Arnett (Donna); I.B. Borecki (Ingrid); P.W. Franks (Paul); S.B. Kritchevsky (Stephen); R.J.F. Loos (Ruth); M. Orho-Melander (Marju); J.I. Rotter (Jerome); N.J. Wareham (Nick); J.C.M. Witteman (Jacqueline); L. Ferrucci (Luigi); G.V. Dedoussis (George); L.A. Cupples (Adrienne); J.A. Nettleton (Jennifer )

    2013-01-01

    textabstractBackground: Macronutrient intake varies substantially between individuals, and there is evidence that this variation is partly accounted for by genetic variants. Objective: The objective of the study was to identify common genetic variants that are associated with macronutrient intake. D

  11. Evaluation of a mid-infrared analyzer for the determination of the macronutrient composition of human milk.

    Science.gov (United States)

    Casadio, Ylenia S; Williams, Tracey M; Lai, Ching T; Olsson, Sofia E; Hepworth, Anna R; Hartmann, Peter E

    2010-11-01

    A mid-infrared human milk analyzer (HMA) is designed to measure the macronutrients in human milk over a wide range of concentrations. Human milk samples (N = 30, 4 different dilutions each) were used to compare the macronutrient levels determined by the HMA to those derived from traditional laboratory methods. There was a small but statistically significant difference in the levels of fat, protein, lactose, total solids, and energy for all samples. These differences were consistent with subtle differences in the chemical principles governing the assays. For higher macronutrient levels, a trend to greater differences between the HMA and the laboratory method was seen, particularly in samples with high fat concentration. The intra-assay variation for the HMA for all macronutrients was less than 4%. It is concluded that that with appropriate sample preparation, the mid-infrared HMA can provide a practical measurement of macronutrients in human milk.

  12. Infant macronutrient composition is associated with differences in cardiovascular structures and function in childhood.

    Science.gov (United States)

    van den Hooven, Edith H; de Jonge, Layla L; Kiefte-de Jong, Jessica C; Raat, Hein; Villamor, Eduardo; Hofman, Albert; Felix, Janine F; Jaddoe, Vincent W V; Moll, Henriette A; Franco, Oscar H

    2013-12-01

    Early-life nutrition may influence cardiovascular development. Not much is known about the associations between dietary composition and cardiovascular risk factors in childhood. We examined the associations of infant macronutrient intake with cardiovascular structures and function in 2882 children participating in a prospective, population-based cohort study. Information on macronutrient intake at the age of 14 mo was obtained from food-frequency questionnaires completed by a parent. Systolic and diastolic blood pressure, carotid-femoral pulse wave velocity (PWV), fractional shortening, and left cardiac structures (left atrial diameter, aortic root diameter, and left ventricular mass) were measured at the age of 6 y. Linear regression analyses were performed by using energy-adjusted macronutrient intakes, adjusted for maternal, child, and other dietary factors. Higher total fat intake was associated with higher carotid-femoral PWV (P-trend = 0.03), whereas higher intakes of total carbohydrate and mono- and disaccharides were associated with lower carotid-femoral PWV. No consistent associations were observed for macronutrient intake with systolic blood pressure, diastolic blood pressure, fractional shortening, and aortic root diameter. Higher intakes of total, saturated, monounsaturated, and polyunsaturated fat were associated with lower left atrial diameter (all P-trend ≤ 0.01), and higher total carbohydrate and mono- and disaccharide intakes were associated with higher left atrial diameter (P-trend cardiovascular structures and function in childhood. Further studies are needed to investigate whether these differences have consequences for the risk of future cardiovascular disease.

  13. The association between macronutrient intake and the metabolic syndrome and its components in type 1 diabetes.

    Science.gov (United States)

    Ahola, Aila J; Harjutsalo, Valma; Thorn, Lena M; Freese, Riitta; Forsblom, Carol; Mäkimattila, Sari; Groop, Per-Henrik

    2017-02-20

    Diet is a major modifiable lifestyle factor that may affect the components of the metabolic syndrome. We aimed to investigate the association between relative proportions of macronutrients and the components of the metabolic syndrome in a population of individuals with type 1 diabetes. In all, 791 individuals without nephropathy, with plausible energy intake and known metabolic syndrome status, taking part in the Finnish Diabetic Nephropathy Study were included in the analyses. Dietary data were collected with a diet record. The association between the relative macronutrient intake and the outcome variables were analysed using multivariable nutrient density substitution models. The relative proportions of dietary macronutrients or fatty acids were not associated with the presence of the metabolic syndrome. In men, however, favouring carbohydrates over fats was associated with lower odds of the waist component, whereas favouring either carbohydrates or fats over proteins was associated with lower odds of the blood pressure component of the metabolic syndrome. In women, substituting carbohydrates for fats was associated with lower HDL-cholesterol concentration. Substituting carbohydrates or fats for alcohol or protein was, in men, associated with lower systolic blood pressure. To conclude, the relative distribution of macronutrients may have some relevance for the metabolic syndrome.

  14. Laboratory Evaluation of Ion-Selective Electrodes for Simultaneous Analysis of Macronutrients in Hydroponic Solution

    Science.gov (United States)

    Automated sensing of macronutrients in hydroponic solution would allow more efficient management of nutrients for crop growth in closed hydroponic systems. Ion-selective microelectrode technology requires an ion-selective membrane or a solid metal material that responds selectively to one analyte in...

  15. Preprandial ghrelin is not affected by macronutrient intake, energy intake or energy expenditure

    Directory of Open Access Journals (Sweden)

    Rumpler William V

    2005-03-01

    Full Text Available Abstract Background Ghrelin, a peptide secreted by endocrine cells in the gastrointestinal tract, is a hormone purported to have a significant effect on food intake and energy balance in humans. The influence of factors related to energy balance on ghrelin, such as daily energy expenditure, energy intake, and macronutrient intake, have not been reported. Secondly, the effect of ghrelin on food intake has not been quantified under free-living conditions over a prolonged period of time. To investigate these effects, 12 men were provided with an ad libitum cafeteria-style diet for 16 weeks. The macronutrient composition of the diets were covertly modified with drinks containing 2.1 MJ of predominantly carbohydrate (Hi-CHO, protein (Hi-PRO, or fat (Hi-FAT. Total energy expenditure was measured for seven days on two separate occasions (doubly labeled water and physical activity logs. Results Preprandial ghrelin concentrations were not affected by macronutrient intake, energy expenditure or energy intake (all P > 0.05. In turn, daily energy intake was significantly influenced by energy expenditure, but not ghrelin. Conclusion Preprandial ghrelin does not appear to be influenced by macronutrient composition, energy intake, or energy expenditure. Similarly, ghrelin does not appear to affect acute or chronic energy intake under free-living conditions.

  16. Cranberry interacts with dietary macronutrients to promote healthy aging in Drosophila.

    Science.gov (United States)

    Wang, Cecilia; Yolitz, Jason; Alberico, Thomas; Laslo, Mara; Sun, Yaning; Wheeler, Charles T; Sun, Xiaoping; Zou, Sige

    2014-08-01

    Botanicals possess numerous bioactivities, and some promote healthy aging. Dietary macronutrients are major determinants of life span. The interaction between botanicals and macronutrients that modulates life span is not well understood. Here, we investigated the effect of a cranberry-containing botanical on life span and the influence of macronutrients on the longevity-related effect of cranberry in Drosophila. Flies were supplemented with cranberry on three dietary conditions: standard, high sugar-low protein, and low sugar-high protein diets. We found that cranberry slightly extended life span in males fed with the low sugar-high protein diet but not with other diets. Cranberry extended life span in females fed with the standard diet and more prominently the high sugar-low protein diet but not with the low sugar-high protein diet. Life-span extension was associated with increased reproduction and higher expression of oxidative stress and heat shock response genes. Moreover, cranberry improved survival of sod1 knockdown and dfoxo mutant flies but did not increase wild-type fly's resistance to acute oxidative stress. Cranberry slightly extended life span in flies fed with a high-fat diet. These findings suggest that cranberry promotes healthy aging by increasing stress responsiveness. Our study reveals an interaction of cranberry with dietary macronutrients and stresses the importance of considering diet composition in designing interventions for promoting healthy aging.

  17. Fusion of spectral and electrochemical sensor data for estimating soil macronutrients

    Science.gov (United States)

    Rapid and efficient quantification of plant-available soil phosphorus (P) and potassium (K) is needed to support variable-rate fertilization strategies. Two methods that have been used for estimating these soil macronutrients are diffuse reflectance spectroscopy in visible and near-infrared (VNIR) w...

  18. Effects of Nitrogen Fertilization and Genotype on Rice Grain Macronutrients and Micronutrients

    Institute of Scientific and Technical Information of China (English)

    LIN Zhao-miao; NING Hui-feng; BI Jun-guo; QIAO Jiang-fang; LIU Zheng-hui; LI Gang-hua; WANG Qiang-sheng; WANG Shao-hua; DING Yan-feng

    2014-01-01

    High nitrogen (N) input features China’s intensive rice production system. To elucidate N and genotype effects on accumulation of macronutrients and micronutrients in grains of japonica rice, and to discuss its significance in rice production, a three-year field experiment involving six japonica rice varieties and seven N treatments were performed. Macronutrients (Ca, Mg, K, and Na) and micronutrients (Cu, Fe, Mn, and Zn) concentrations in brown and milled rice were measured using an atomic absorption spectrophotometer. For macronutrients, no consistently significant effect of N was detected in both brown and milled rice. For micronutrients, N showed significant effect, especially in lowering Zn accumulation in brown and milled rice. In addition, N tended to increase Fe concentration in milled rice. Genotype showed larger effect on distribution of minerals in milled rice than N. The high-yielding variety, Wuyunjing 7, accumulated larger proportion of Mg, K, and Zn in the milled rice as compared with the other five varieties, and could be of value for rice breeding programs aiming at high nutritional quality. The results demonstrated differences in response to N between macronutrients and micronutrients, and are of significance for coping with‘hidden hunger’ both in humans and crops through agronomical practices.

  19. Myocardial macronutrient transporter adaptations in the adult pregestational female intrauterine and postnatal growth-restricted offspring.

    Science.gov (United States)

    Abbasi, Afshan; Thamotharan, Manikkavasagar; Shin, Bo-Chul; Jordan, Maria C; Roos, Kenneth P; Stahl, Andreas; Devaskar, Sherin U

    2012-06-01

    Associations between exponential childhood growth superimposed on low birth weight and adult onset cardiovascular disease with glucose intolerance/type 2 diabetes mellitus exist in epidemiological investigations. To determine the metabolic adaptations that guard against myocardial failure on subsequent exposure to hypoxia, we compared with controls (CON), the effect of intrauterine (IUGR), postnatal (PNGR), and intrauterine and postnatal (IPGR) calorie and growth restriction (n = 6/group) on myocardial macronutrient transporter (fatty acid and glucose) -mediated uptake in pregestational young female adult rat offspring. A higher myocardial FAT/CD36 protein expression in IUGR, PNGR, and IPGR, with higher FATP1 in IUGR, FATP6 in PNGR, FABP-c in PNGR and IPGR, and no change in GLUT4 of all groups was observed. These adaptive macronutrient transporter protein changes were associated with no change in myocardial [(3)H]bromopalmitate accumulation but a diminution in 2-deoxy-[(14)C]glucose uptake. Examination of the sarcolemmal subfraction revealed higher basal concentrations of FAT/CD36 in PNGR and FATP1 and GLUT4 in IUGR, PNGR, and IPGR vs. CON. Exogenous insulin uniformly further enhanced sarcolemmal association of these macronutrient transporter proteins above that of basal, with the exception of insulin resistance of FATP1 and GLUT4 in IUGR and FAT/CD36 in PNGR. The basal sarcolemmal macronutrient transporter adaptations proved protective against subsequent chronic hypoxic exposure (7 days) only in IUGR and PNGR, with notable deterioration in IPGR and CON of the echocardiographic ejection fraction. We conclude that the IUGR and PNGR pregestational adult female offspring displayed a resistance to insulin-induced translocation of FATP1, GLUT4, or FAT/CD36 to the myocardial sarcolemma due to preexistent higher basal concentrations. This basal adaptation of myocardial macronutrient transporters ensured adequate fatty acid uptake, thereby proving protective against

  20. Effects of proportions of dietary macronutrients on glucocorticoid metabolism in diet-induced obesity in rats.

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    Roland H Stimson

    Full Text Available Tissue glucocorticoid levels in the liver and adipose tissue are regulated by regeneration of inactive glucocorticoid by 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1 and inactivation by 5alpha- and 5beta-reductases. A low carbohydrate diet increases hepatic 11beta-HSD1 and reduces glucocorticoid metabolism during weight loss in obese humans. We hypothesized that similar variations in macronutrient proportions regulate glucocorticoid metabolism in obese rats. Male Lister Hooded rats were fed an obesity-inducing ad libitum 'Western' diet (37% fat, n = 36 for 22 weeks, then randomised to continue this diet (n = 12 or to switch to either a low carbohydrate (n = 12 or a moderate carbohydrate (n = 12 diet for the final 8 weeks. A parallel lean control group were fed an ad libitum control diet (10% fat, n = 12 throughout. The low and moderate carbohydrate diets decreased hepatic 11beta-HSD1 mRNA compared with the Western diet (both 0.7+/-0.0 vs 0.9+/-0.1 AU; p<0.01, but did not alter 11beta-HSD1 in adipose tissue. 5Alpha-reductase mRNA was increased on the low carbohydrate compared with the moderate carbohydrate diet. Compared with lean controls, the Western diet decreased 11beta-HSD1 activity (1.6+/-0.1 vs 2.8+/-0.1 nmol/mcg protein/hr; p<0.001 and increased 5alpha-reductase and 5beta-reductase mRNAs (1.9+/-0.3 vs 1.0+/-0.2 and 1.6+/-0.1 vs 1.0+/-0.1 AU respectively; p<0.01 in the liver, and reduced 11beta-HSD1 mRNA and activity (both p<0.01 in adipose tissue. Although an obesity-inducing high fat diet in rats recapitulates the abnormal glucocorticoid metabolism associated with human obesity in liver (but not in adipose tissue, a low carbohydrate diet does not increase hepatic 11beta-HSD1 in obese rats as occurs in humans.

  1. Role of Macronutrients and Micronutrients in DNA Damage: Results From a Food Frequency Questionnaire

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    Carina Ladeira

    2017-02-01

    Full Text Available The links between diet and genomic instability have been under investigation for several decades, and evidence suggests a significant causal or preventive role for various dietary factors. This study investigates the influence of macronutrients (calories, protein, and glucides and micronutrients, such as vitamins and minerals, as assessed by a food frequency questionnaire, on genotoxicity biomarkers measured by cytokinesis-blocked micronucleus assay and comet assay. The results found significant positive and negative correlations. Micronucleus frequency tends to increase with higher intake of caffeine, calcium, magnesium, zinc, and protein ( P  < .05, Spearman correlation. Calorie and omega-6 intakes are negatively correlated with DNA damage measured by the comet assay. These results are somewhat controversial because some of the correlations found are contrary to dominant views in the literature; however, we suggest that unraveling the association between diet and genetic instability requires a much better understanding of the modulating role of macronutrients and micronutrients.

  2. Role of Macronutrients and Micronutrients in DNA Damage: Results From a Food Frequency Questionnaire.

    Science.gov (United States)

    Ladeira, Carina; Carolino, Elisabete; Gomes, Manuel C; Brito, Miguel

    2017-01-01

    The links between diet and genomic instability have been under investigation for several decades, and evidence suggests a significant causal or preventive role for various dietary factors. This study investigates the influence of macronutrients (calories, protein, and glucides) and micronutrients, such as vitamins and minerals, as assessed by a food frequency questionnaire, on genotoxicity biomarkers measured by cytokinesis-blocked micronucleus assay and comet assay. The results found significant positive and negative correlations. Micronucleus frequency tends to increase with higher intake of caffeine, calcium, magnesium, zinc, and protein (P < .05, Spearman correlation). Calorie and omega-6 intakes are negatively correlated with DNA damage measured by the comet assay. These results are somewhat controversial because some of the correlations found are contrary to dominant views in the literature; however, we suggest that unraveling the association between diet and genetic instability requires a much better understanding of the modulating role of macronutrients and micronutrients.

  3. Role of Macronutrients and Micronutrients in DNA Damage: Results From a Food Frequency Questionnaire

    Science.gov (United States)

    Ladeira, Carina; Carolino, Elisabete; Gomes, Manuel C; Brito, Miguel

    2017-01-01

    The links between diet and genomic instability have been under investigation for several decades, and evidence suggests a significant causal or preventive role for various dietary factors. This study investigates the influence of macronutrients (calories, protein, and glucides) and micronutrients, such as vitamins and minerals, as assessed by a food frequency questionnaire, on genotoxicity biomarkers measured by cytokinesis-blocked micronucleus assay and comet assay. The results found significant positive and negative correlations. Micronucleus frequency tends to increase with higher intake of caffeine, calcium, magnesium, zinc, and protein (P < .05, Spearman correlation). Calorie and omega-6 intakes are negatively correlated with DNA damage measured by the comet assay. These results are somewhat controversial because some of the correlations found are contrary to dominant views in the literature; however, we suggest that unraveling the association between diet and genetic instability requires a much better understanding of the modulating role of macronutrients and micronutrients. PMID:28469462

  4. Deficiency of macronutrients in sangra d’água (Croton urucurana, Baill. seedlings

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    Maria Claudia Mendes Sorreano

    2011-09-01

    Full Text Available This study had the objectives of inducing and describing deficiency symptoms of nitrogen, phosphorus, potassium, calcium, magnesium and sulfur, and evaluating the effect of nutrient omission on the foliar mineral composition of “sangra d’água” (Croton urucurana young plants. The experiment was carried out in a green house and used the technique of diagnosis by subtraction. The experimental design was of randomized blocks, with seven treatments and three replicates. Macronutrient omission led to morphological alterations expressed by visual symptoms being the first symptons occurring on the treatments with omission of N, K, Ca and Mg treatments, and later on the treatments with omission of P and S. Growth parameters, namely height, diameter, number of leaves and of branches were affected by the treatments with omission of N, Ca and Mg. Dry matter yield was not significantly decreased by the omission of macronutrients.

  5. Macronutrient composition of nickel-treated wheat under different sulfur concentrations in the nutrient solution.

    Science.gov (United States)

    Matraszek, Renata; Hawrylak-Nowak, Barbara; Chwil, Stanisław; Chwil, Mirosława

    2016-03-01

    The effect of different sulfate(VI) sulfur (2, 6, and 9 mM S) levels and nickel(II) chloride (0, 0.0004, 0.04 and 0.08 mM Ni) in the nutrient solution on productivity and macronutrient (N, P, K, Ca, Mg, S) status and accumulation in spring wheat (Triticum aestivum L.) Zebra cv. was studied. Ni treatment reduced the biomass and disturbed the balance and accumulation of macronutrients in wheat. Intensive S nutrition, especially with 6 mM S, at least partially increased the biomass, improved ionic equilibrium, and enhanced nutrient accumulation in Ni-exposed plants in spite of increased Ni accumulation. Admittedly, the dose 9 mM S reduced Ni accumulation in shoots but increased accumulation thereof in roots. Compared to 6 mM, the dose 9 mM was less effective in improving the mineral status of Ni-treated wheat.

  6. The effects of macronutrient composition of the larval diet on life history traits and pigmentation in Drosophila virilis

    OpenAIRE

    Rodrigues, Marisa Almeida

    2014-01-01

    Tese de mestrado. Biologia (Biologia Evolutiva e do Desenvolvimento). Universidade de Lisboa, Faculdade de Ciências, 2014 One of the main contributions for an animal’s life success is an optimal nutrition. Macronutrients, such as proteins and carbohydrates, are essential for organism development, determining for example, the size of the body and or reproductive capacity. Different animals use macronutrients differently. To achieve the necessary requirements, generalist species use a wide r...

  7. The diet quality index evaluates the adequacy of energy provided by dietary macronutrients

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    Aline MENDES

    2015-08-01

    Full Text Available Objective To investigate the relationship between macronutrient intake adequacy and the national diet quality index score. Methods The study analyzed a representative sample of 1,662 individuals from the municipality of São Paulo who participated in a cross-sectional study called Health Survey-Capital (2008/2009. Two 24-hour recalls were collected. Habitual intake was determined by the Multiple Source Method. The Brazilian index was calculated as suggested, and macronutrient adequacy was given by the World Health Organization and Food and Agriculture Organization recommendations. A generalized linear model verified the relationship between the Brazilian index and macronutrient adequacy. All analyses with a descriptive level below 0.05 were considered significant. The analyses were performed by the software Stata 12.0, survey mode. Results The vast majority (91% of the population had inappropriate macronutrient intakes, and the total median Brazilian index score was 61.3 points (interquartile range=10.1. The total Brazilian index score of individuals with high lipid intake was worse than that of individuals with proper lipid intake (β=0,96; p=0,004, while those with high protein intake had a better score (β=1,10; p=0,003 than those with proper protein intake. Conclusion The revised Brazilian Healthy Eating Index assesses diet quality properly regarding high lipid intake, but it has some limitations regarding high protein intake according to the World Health Organization and Food and Agriculture Organization recommendations. New studies should investigate the possibility of adapting this index to the World Health Organization and Food and Agriculture Organization recommendations.

  8. Preprandial ghrelin is not affected by macronutrient intake, energy intake or energy expenditure

    OpenAIRE

    Rumpler William V; Rhodes Donna G; Kramer Matthew; Paul David R

    2005-01-01

    Abstract Background Ghrelin, a peptide secreted by endocrine cells in the gastrointestinal tract, is a hormone purported to have a significant effect on food intake and energy balance in humans. The influence of factors related to energy balance on ghrelin, such as daily energy expenditure, energy intake, and macronutrient intake, have not been reported. Secondly, the effect of ghrelin on food intake has not been quantified under free-living conditions over a prolonged period of time. To inve...

  9. Effects of Macronutrients on Cardiovascular Responses in Type 2 Diabetics and Healthy Subjects

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    M Hoseini

    2004-07-01

    Full Text Available Introduction: It is felt that there is an information void regarding the effect of macronutrients on cardiovascular responses such as cardiac output,heart rate,stroke volume,systolic blood pressure,diastolic blood pressure and mean arterial pressure, therefore, this study was designed to explore these effects at Shaheed Beheshti University in 2001. Materials & Methods: This clinical trial was carried out on 10 healthy subjects and 15 type 2 diabetics. Cardiovascular responses defined before and 15,30,60,90 and 120 minutes after the intake of wheat starch,sodium caseinat and olive oil. The calorie level was 10 kcal per kg of ideal body weight. Statistical analyses were done by analysis of variance with repeated measures, independent - t test and dependent- t test. Results : The age of healthy subjects (4 women ,6menwas 36.6±5.8(mean±SDyr,body mass index was 24±1.2Kg/m² , age for the type 2 diabetics (4 women ,11menwas 38.9±5.2(mean ±SD yr , body mass index was 24±1.6Kg/m². In healthy subjects, macronutrients caused marked and gradually developing postprandial increases in cardiac output, while in type 2 diabetics,cardiac output had no changes. In healthy subjects, systolic blood pressure and mean arterial pressure rose after the ingestion of macronutrients (P<0.05. In type 2 diabetics after the ingestion of macronutrients there was a fall in systolic blood pressure and mean arterial pressure(P<0.05.In both groups, diastolic blood pressure showed no changes . Conclusion: There were considerable differences in the speed of development and the pattern of the cardiovascular responses between type 2 diabetics and healthy subjects (P<0.05.Finally we conclude that diabetes in the early stages probably involves the cardiovascular system.

  10. Maternal Macronutrient Consumption and the Developmental Origins of Metabolic Disease in the Offspring

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    Stephanie M. Kereliuk

    2017-07-01

    Full Text Available Recent research aimed at understanding the rise in obesity and cardiometabolic disease in children suggests that suboptimal maternal nutrition conditions organ systems and physiological responses in the offspring contributing to disease development. Understanding the mechanisms by which the macronutrient composition of the maternal diet during pregnancy or lactation affects health outcomes in the offspring may lead to new maternal nutrition recommendations, disease prevention strategies and therapies that reduce the increasing incidence of cardiometabolic disease in children. Recent mechanistic animal model research has identified how excess fats and sugars in the maternal diet alter offspring glucose tolerance, insulin signaling and metabolism. Maternal nutrition appears to influence epigenetic alterations in the offspring and the programming of gene expression in key metabolic pathways. This review is focused on experimental studies in animal models that have investigated mechanisms of how maternal consumption of macronutrients affects cardiometabolic disease development in the offspring. Future research using “-omic” technologies is essential to elucidate the mechanisms of how altered maternal macronutrient consumption influences the development of disease in the offspring.

  11. Water dephts and macronutrients accumulation in 'pérola' pineapple irrigated by drip

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    Uirá do Amaral

    2014-09-01

    Full Text Available Brazil is one of the largest pineapple producers worldwide, and those fruits are for the juice industry and the in natura market. Its cultivation requires high technology investment by using irrigation and balanced fertilization. However, little is known about the influence of drip irrigation on nutrient uptake by pineapple plants. This study aimed to evaluate the influence of different irrigation depths on nutrients accumulation by 'Pérola' pineapples grown in northern region of Minas Gerais State, Brazil. The experimental design was in randomized blocks with five treatments referring to: 30% of Class A Evaporation Pan (ECA; 50% of ECA; 70% of ECA; 100% of ECA; and 150% of ECA. To determine the levels of macronutrients and dry matter, the plants were separated in root, stem, leaves, 'D' leaf, crown, fruit and whole plant. The sequence of macronutrients accumulated in the whole plant was K>N>Ca>P>Mg. The fruits exported from the cultivated area the following amounts of macronutrients: 17.52 kg ha-1 of K (12.8%; 16.91 kg ha-1 of N (20.7%; 10.77 kg ha-1 of Ca (15.9%, 1.29 kg ha-1 of P (12.4% and 1.04 kg ha-1 of Mg (20.5%. The irrigation depths that provided the maximum N, P, K and Ca accumulation in the whole plant are 53.6, 61.6, 54.5 and 60.2% of ECA, respectively.

  12. [Intakes of energy and macronutrients in pregnant women in the northeast of Mexico].

    Science.gov (United States)

    Tijerina Sáenz, Alexandra; Ramírez López, Erik; Meneses Valderrama, Víctor Manuel; Martínez Garza, Nancy Edith

    2014-09-01

    Descriptive and transversal study, first to report the dietary intake of energy and macronutrients in pregnant women in the northeast of Mexico. Convenience sample of 125 pregnant women (15-45 years of age) in the third trimester, who were prenatal patients in the Hospital Regional Materno Infantil, Nuevo León, Mexico. It was reported the level of studies, marital and professional status, weight, height and body mass index (BMI). Diet was evaluated by 24-hour food recalls, in 3 non-consecutive days. There were analyzed the intake of energy and the percentage contribution of calories from macronutrients according to the recommendations of intake of pregnant women. Intake of energy was 1683,8 Cal/day. The caloric contribution of saturated fat was higher than the recommendation in 53.6% of women. 76.8% of participants ate more than 55% of energy from carbohydrates, while 86.4% ate more sugars than the amount suggested. The median intake of protein was 12.0% of total energy intake. 75% of participants consumed less than 22,5 g of total dietary fiber. The relevance of knowing the intakes of energy and macronutrients in pregnant women may be due to the possible influence of diet over the child's appetite and maternal complications. Results of this study suggest the need to provide women with adequate nutritional recommendations since the first trimester of gestation, according to their nutritional status and social environment.

  13. Assessment of macronutrient and micronutrient intake in women with anorexia nervosa.

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    Hadigan, C M; Anderson, E J; Miller, K K; Hubbard, J L; Herzog, D B; Klibanski, A; Grinspoon, S K

    2000-11-01

    The purpose of this study is to evaluate the accuracy of diet history compared to observed food intake in the nutritional assessment of women with anorexia nervosa (AN) and healthy age-matched controls. One-month diet history was compared to 1-day observed food intake in 30 women with AN and 28 control subjects. Reported intake by diet history was similar to observed intake for macronutrient composition and fat intake for patients with AN. Reported energy intake was higher than observed intake (1,602 +/- 200 kcal vs. 1,289 +/- 150 kcal, p assessed by diet history. In contrast to patients with AN, diet history did not correlate with observed intake of energy, macronutrients, or most micronutrients among the controls. Diet history is an accurate tool to assess fat intake and macronutrient composition in patients with AN and demonstrates significant micronutrient deficiencies in this population. The agreement between total energy intake and predicted energy expenditure supports the overall utility of the diet history in the nutritional assessment of patients with AN. Copyright 2000 by John Wiley & Sons, Inc.

  14. Food and macronutrient intake of male adolescent Kalenjin runners in Kenya.

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    Christensen, Dirk L; Van Hall, Gerrit; Hambraeus, Leif

    2002-12-01

    A nutritional survey based on twelve adolescent male Kalenjin runners in Kenya during a 2-week field study was carried out in order to determine the composition of their diet and make a comparison with macronutrient recommendations for athletes. Food samples were collected for analysis of macronutrient distribution and energy content from main meals and the macronutrient distribution and energy content of additional food intake were based on the information of a 24 h recall interview and estimated from food tables. The diet of the Kalenjin runners was very high in carbohydrate (71 % 8.7 g/kg body weight per d) and very low in fat (15 %). Intake of total protein (13 %; 1.6 g/kg body weight per d) was above the daily intake recommended by the Food and Agriculture Organization/World Health Organization/United Nations University (FAO/WHO/UNU), while essential amino acid intake was estimated to be in the borderline-to-low range based on FAO/WHO/UNU recommendations for children staple food (81 %). The diet of the Kalenjin runners met recommendations for endurance athletes for total protein and most essential amino acid intake as well as carbohydrate intake even though it was based on a small range of food items.

  15. Nutritional disorder of lettuce cv. Veronica in nutrient solution with suppressed macronutrients

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    Thiago Batista Firmato de Almeida

    2011-06-01

    Full Text Available Lettuce is the most popular of the leafy vegetables. It is known worldwide and its consumption occurs mainly in the natural form. The objective was to evaluate the effect of macronutrient omission on the growth and nutritional status of the lettuce cv. Veronica, and to describe the visual symptoms of nutritional deficiency. The treatments complete consisted of the solution and the individual omission of N, P, K, Ca, Mg and S, under a completely randomized design with three replications. Plants were grown in Hoagland & Arnon, in pots (8L. At 56 days after transplant we evaluated plant height, leaf number, leaf area, SPAD index, dry matter of shoots, roots and whole plant, levels of macronutrients in shoots and roots, and the nature of nutritional disorders. The omission of nutrients affected the growth variables. The nutrients found in lettuce plants from nutrient solution and the complete omission in the shoot were, respectively, N= 23.2 to 9.5, P= 5.4 to 1.3, K= 58,9 to 3.2, Ca= 12.1 to 3.6, Mg= 5.5 to 0.7 and S= 3.2 to 1.5g.kg-1. The omission of macronutrients caused quality losses, since it affected the nutrition of the vegetables and this resulted in morphological changes, reflected as symptoms of deficiency for each nutrient.

  16. Accumulation of macronutrients by weed and corn in coexistence in soil with different fertility managements

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    Christiane Augusta Diniz Melo

    2015-04-01

    Full Text Available The understanding of weed interference on crops is very important in agricultural systems. However, there is little known about the influence of soil fertility management in competitive relations between plants. The objective of this study was to evaluate the effects of mutual interference between weeds and corn on the content of macronutrients under different soil fertility managements. The experimental test was conducted in a greenhouse, considering four soil fertility managements (with calcium and magnesium silicate and fertilization; with limestone and fertilization; without correction of acidity, but with fertilization; without correction of acidity and without fertilization and eleven crops (five arrangements of competition between Zea mays and the weeds Urochloa brizantha, Ipomoea grandifolia, Conyza canadensis, Hyptis suaveolens and Bidens pilosa, plus the six species in monoculture. Corn had reductions exceeding 50% in the content of all macronutrients under interference of U. brizantha. Additionally, U. brizantha and B. pilosa in competition with corn has high ability to extract macronutrients in the four soil conditions. Calcium and magnesium silicate and limestone influenced variable on nutrient accumulation by weeds in monoculture or under interference. Corn grown in soil amended with silicate suffered greater competition with weeds compared to grown in soil amended with lime. U. brizantha was the specie most damaging to the crop. B. pilosa showed high potential for nutrient cycling in the four soil fertility management.

  17. Omissão de macronutrientes em plantas de amendoim Deficiency of macronutrients in peanuts

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    Francisco Solano de Oliveira Rodrigues Filho

    1988-01-01

    Full Text Available Plantas de amendoim Arachis hypogaea L. 'Tatu' foram cultivadas em condições de casa de vegetação, em vasos de Mitscherlich contendo areia lavada e irrigados com solução nutritiva completa e com soluções nutritivas com a omissão de cada macronutriente (N, P, K, Ca, Mg e S. As plantas mostraram sintomas de deficiência de macronutrientes, com exceção do fósforo, na ausência de cada elemento, relacionados com os seus baixos teores e redução no crescimento, desenvolvimento e produção de matéria seca.Peanut plants (Arachis hypogaea L. were cultivated in washed sand, under greenhouse conditions, irrigated with a complete nutrient solution and nutrient solutions with absence of each macronutrient (N, P, K, Ca, Mg and S. Typical symptoms of macronutrient deficiencies were observed, except for phosphorus, related to the content of the element in the plant. The absence of macronutrients also influenced the plant dry matter production, development and height.

  18. Energy and macronutrient composition of breakfast affect gastric emptying of lunch and subsequent food intake, satiety and satiation.

    Science.gov (United States)

    Clegg, Miriam; Shafat, Amir

    2010-06-01

    Satiety and food intake are closely related to gastrointestinal transit and specifically gastric emptying. High-fat (HF) meals empty more slowly from the stomach yet are less satiating than isoenergetic low-fat (LF) meals. The current study examines how gastric emptying and satiety at lunch are affected by energy and macronutrient content of breakfast. Nine male volunteers consumed either (1) a HF breakfast, (2) a LF breakfast isoenergetic to HF (LFE) or (3) a LF breakfast of equal mass to HF (LFM). Gastric emptying half time measured using the sodium [(13)C] acetate breath test was delayed after HF compared to LF meals (HF: 102 + or - 11, LFE: 96 + or - 13, LFM: 95 + or - 13 min, mean + or - SD). Fullness increased and desire to eat decreased following the LFE breakfast measured using visual analogue scales. Eating a HF breakfast increased the energy, fat and protein from an ad libitum buffet meal given 4h after lunch. In conclusion, eating a HF breakfast delayed gastric emptying of lunch and increased food intake 7 h later compared to a LFM breakfast. These data suggest both mass and energy content of food regulate subsequent appetite and feeding and demonstrate the hyperphagic effect of a single HF meal.

  19. The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice

    Science.gov (United States)

    Solon-Biet, Samantha M.; McMahon, Aisling C.; Ballard, J. William O.; Ruohonen, Kari; Wu, Lindsay E.; Cogger, Victoria C.; Warren, Alessandra; Huang, Xin; Pichaud, Nicolas; Melvin, Richard G.; Gokarn, Rahul; Khalil, Mamdouh; Turner, Nigel; Cooney, Gregory J.; Sinclair, David A.; Raubenheimer, David; Le Couteur, David G.; Simpson, Stephen J.

    2016-01-01

    Summary The fundamental questions of what represents a macronutritionally balanced diet and how this maintains health and longevity remain unanswered. Here, the Geometric Framework, a state-space nutritional modeling method, was used to measure interactive effects of dietary energy, protein, fat, and carbohydrate on food intake, cardiometabolic phenotype, and longevity in mice fed one of 25 diets ad libitum. Food intake was regulated primarily by protein and carbohydrate content. Longevity and health were optimized when protein was replaced with carbohydrate to limit compensatory feeding for protein and suppress protein intake. These consequences are associated with hepatic mammalian target of rapamycin (mTOR) activation and mitochondrial function and, in turn, related to circulating branched-chain amino acids and glucose. Calorie restriction achieved by high-protein diets or dietary dilution had no beneficial effects on lifespan. The results suggest that longevity can be extended in ad libitum-fed animals by manipulating the ratio of macronutrients to inhibit mTOR activation. PMID:24606899

  20. Macronutrients contribution from beverages according to sex and age: findings from the ANIBES Study in Spain.

    Science.gov (United States)

    Ruiz-Moreno, Emma; Rodríguez-Alonso, Paula; Ávila-Torres, José Manuel; Valero-Gaspar, Teresa; Del Pozo de la Calle, Susana; Varela-Moreiras, Gregorio

    2016-07-13

    Methodologies and procedures used in dietary surveys have been widely developed with the aim of evaluating the nutritional status of a population. However, beverages are often either disregarded at national and international assessment of nutrients intake or poorly mentioned. Moreover, there is no standardized questionnaire developed as a research tool for the evaluation of beverages intake in the general population. Moreover, the contribution of different beverages to macronutrients intake is rarely provided. The latter in the context of a continuous expansion and innovation of the beverages market in Spain. Therefore, the main goal of the present study was to evaluate non-alcoholic and alcoholic beverages macronutrients contribution in the ANIBES study in Spain (9-75 years old).As expected, those contributed to dietary macronutrient intake mainly as total carbohydrates and sugar. The contribution to other macronutrients (proteins and lipids) by the beverage groups was of much less importance. For non-alcoholic beverages, contribution to carbohydrates was much higher in younger populations (children: 10.91 ± 9.49%, mean ± SD for boys and 9.46 ± 8.83% for girls; adolescents: 11.97 ± 11.26% for men and 13.77 ± 10.55% in women) than in adults: 9.01 ± 9.84% for men and 7.77 ± 8.73% in women. Finally, a much lower contribution was observed in the elderly: 4.22 ± 6.10% for men and 4.46 ± 6.56% for women. No sex differences, however, across all age groups were found. Results for sugar contribution showed a similar trend: children (23.14 ± 19.00% for boys and 19.77 ± 17.35% for girls); adolescents (28.13 ± 24.17% for men and 29.83 ± 21.82% in women); adults 20.42 ± 20.35% for men and 16.95 ± 17.76% in women, p ≤ 0.01; and elderly: 14.63% ± 9.97 for men and 9.33 ± 12.86% in women. The main contribution corresponded to sugared soft drinks, juices and nectars, more relevant and significant in the younger populations. As for alcoholic beverages, the

  1. Linking trace element variations with macronutrients and major cations in marine mussels Mytilus edulis and Perna viridis.

    Science.gov (United States)

    Liu, Fengjie; Wang, Wen-Xiong

    2015-09-01

    Marine mussels have long been used as biomonitors of contamination of trace elements, but little is known about whether variation in tissue trace elements is significantly associated with those of macronutrients and major cations. The authors examined the variability of macronutrients and major cations and their potential relationships with bioaccumulation of trace elements. The authors analyzed the concentrations of macronutrients (C, N, P, S), major cations (Na, Mg, K, Ca), and trace elements (Al, V, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Mo, Cd, Ba, Pb) in the whole soft tissues of marine mussels Mytilus edulis and Perna viridis collected globally from 21 sites. The results showed that 12% to 84% of the variances in the trace elements was associated with major cations, and the tissue concentration of major cations such as Na and Mg in mussels was a good proxy for ambient seawater concentrations of the major cations. Specifically, bioaccumulation of most of the trace elements was significantly associated with major cations, and the relationships of major cations with trace cations and trace oxyanions were totally opposite. Furthermore, 14% to 69% of the variances in the trace elements were significantly associated with macronutrients. Notably, more than half of the variance in the tissue concentrations of As, Cd, V, Ba, and Pb was explained by the variance in macronutrients in one or both species. Because the tissue macronutrient concentrations were strongly associated with animal growth and reproduction, the observed coupling relationships indicated that these biological processes strongly influenced the bioaccumulation of some trace elements. The present study indicated that simultaneous quantification of macronutrients and major cations with trace elements can improve the interpretation of biomonitoring data. © 2015 SETAC.

  2. Differential vascular dysfunction in response to diets of differing macronutrient composition: a phenomenonological study

    Directory of Open Access Journals (Sweden)

    Cassidy Roslyn

    2007-06-01

    Full Text Available Abstract Background Vascular dysfunction can develop from consumption of an energy-rich diet, even prior to the onset of obesity. However, the roles played by different dietary components remain uncertain. While attempting to develop models of obesity in a separate study, we observed that two high-energy diets of differing macronutrient compositions affected vascular function differently in overweight rats. Methods Male Wistar rats (n = 6/group were fed diets providing varying percentages of energy from fat and carbohydrate (CHO. For 10 weeks, they were fed either chow, as control diet (10% of energy from fat; 63% from CHO, chow supplemented with chocolate biscuit (30% fat; 56% CHO or a high-fat diet (45% fat; 35% CHO. Blood concentrations of biochemical markers of obesity were measured, and epididymal fat pads weighed as a measure of adiposity. Mesenteric arteries were dissected and their contractile and relaxant properties analysed myographically. Data were tested by analysis of variance (ANOVA. Results Weight gain and plasma concentrations of glucose, insulin and leptin were similar in all groups. However, biscuit-fed animals showed increased food intake (+27%; p p p p p Conclusion Vascular dysfunction resulting from consumption of a high-fat or combined relatively high-fat/high-CHO diet occurs through different physiological processes, which may be attributable to their differing macronutrient compositions. Combining potentially atherogenic macronutrients induces more extensive vascular impairment than that of high-fat alone, and may be attributable to the more marked dyslipidaemia observed with such a diet. Thus, these findings help clarify the role of dietary components in vascular impairment, which has implications for clinical approaches to preventing cardiovascular disease.

  3. Macronutrient optimization and seasonal diet mixing in a large omnivore, the grizzly bear: a geometric analysis.

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    Sean C P Coogan

    Full Text Available Nutrient balance is a strong determinant of animal fitness and demography. It is therefore important to understand how the compositions of available foods relate to required balance of nutrients and habitat suitability for animals in the wild. These relationships are, however, complex, particularly for omnivores that often need to compose balanced diets by combining their intake from diverse nutritionally complementary foods. Here we apply geometric models to understand how the nutritional compositions of foods available to an omnivorous member of the order Carnivora, the grizzly bear (Ursus arctos L., relate to optimal macronutrient intake, and assess the seasonal nutritional constraints on the study population in west-central Alberta, Canada. The models examined the proportion of macronutrients that bears could consume by mixing their diet from food available in each season, and assessed the extent to which bears could consume the ratio of protein to non-protein energy previously demonstrated using captive bears to optimize mass gain. We found that non-selective feeding on ungulate carcasses provided a non-optimal macronutrient balance with surplus protein relative to fat and carbohydrate, reflecting adaptation to an omnivorous lifestyle, and that optimization through feeding selectively on different tissues of ungulate carcasses is unlikely. Bears were, however, able to dilute protein intake to an optimal ratio by mixing their otherwise high-protein diet with carbohydrate-rich fruit. Some individual food items were close to optimally balanced in protein to non-protein energy (e.g. Hedysarum alpinum roots, which may help explain their dietary prevalence. Ants may be consumed particularly as a source of lipids. Overall, our analysis showed that most food available to bears in the study area were high in protein relative to lipid or carbohydrate, suggesting the lack of non-protein energy limits the fitness (e.g. body size and reproduction and

  4. The excesive intake of macronutrients: does it influence the sportive performances of young cyclists?

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    J. L. Sánchez-Benito

    Full Text Available The purpose was to determine whether 34 young Spanish males belonging to a cyclist team, follows the optimal macronutrients intake based on the ecommended dietary guidelines. The deficits in nutrition jeopardise the sportive performances, but what about the diets with excessive intake of macronutrients? Furthermore, is there an association between their sportive achievements and the psychological profile? Surely, but the problem is to determine which psychological variables are involved. Method: Nutritional evaluation based on Nutrients intake questionnaire of 7 consecutive days. Results: Cyclists consume an excessive quantity of proteins and lipids in their diets. The average consumption of proteins is 16,36% of their caloric intake (the recommended quantity is less than 10%. The average consumption of fats is 38,71% (the recommended is less than 30%. The same tendency is found in the homologous Spanish young people of the enKID study, where the percentage of energy from fat and saturated fat is much higher than the recommended one. The cyclists consume insufficient quantities of carbohydrates (average is 44, 94% of their caloric intake, the recommended is more than 60%, therefore the reload of their glycogen stores may not be complete on each competition stage. No association has been found between the excessive intake of referred macronutrients and the achieved sport performances. Conclusion: This work contributes to the knowledge of the diets of very active young cyclists. Excessive intake of proteins and fats do not jeopardise their sportive performances. The commonly studied psychological variables in sport, are not determinant of sportive achievements of young cyclists; additional work is needed to determine the psychological profile playing a determinant role in success of young cyclists.

  5. Breast milk macronutrient composition and the associated factors in urban Chinese mothers

    Institute of Scientific and Technical Information of China (English)

    Yang Titi; Zhang Yumei; Ning Yibing; You Lili; Ma Defu; Zheng Yingdong; Yang Xiaoguang

    2014-01-01

    Background Infancy is a critical period of growth and physiological development,in which breast milk is the best source of nutrients.Compared to western countries,research on breast milk of Chinese population are limited.Thus,it is necessary to measure breast milk energy and macronutrient concentrations of healthy urban Chinese mothers at different lactation stages,to expand the database of milk composition of Chinese population,and to examine whether dietary or other maternal factors can affect the levels of macronutrients in breast milk.Methods Breast milk of full expression of one side breast from 436 urban Chinese lactating mothers at 5-11 days,12-30 days,31-60 days,61-120 days,and 121-240 days postpartum was obtained at 9:00 a.m.to 11:00 a.m.Total energy,lactose,protein,and fat contents were measured.24-hour dietary recall was surveyed,and maternal nutrient intakes were analyzed.Results Milk composition changed over the course of lactation and large individual variations were documented.The concentrations were 61.3 kcal/dl for total energy,7.1 g/dl for lactose,0.9 g/dl for protein,and 3.4 g/dl for fat in mature milk.Stage of lactation was a strong factor affecting milk composition.Minimal evidence was found for associations between maternal current dietary intake and milk macronutrient concentration,consistently with prior research.Maternal body mass index (BMI) was positively associated with milk fat content,to a greater extent than did dietary intake.All other maternal characteristics were not significant for milk composition.Conclusion These findings suggest that milk composition is generally weakly associated with maternal factors except for stage of lactation,and is likely to be more susceptible to long-term maternal nutritional status than short-term dietary fluctuation.

  6. Macronutrient optimization and seasonal diet mixing in a large omnivore, the grizzly bear: a geometric analysis.

    Science.gov (United States)

    Coogan, Sean C P; Raubenheimer, David; Stenhouse, Gordon B; Nielsen, Scott E

    2014-01-01

    Nutrient balance is a strong determinant of animal fitness and demography. It is therefore important to understand how the compositions of available foods relate to required balance of nutrients and habitat suitability for animals in the wild. These relationships are, however, complex, particularly for omnivores that often need to compose balanced diets by combining their intake from diverse nutritionally complementary foods. Here we apply geometric models to understand how the nutritional compositions of foods available to an omnivorous member of the order Carnivora, the grizzly bear (Ursus arctos L.), relate to optimal macronutrient intake, and assess the seasonal nutritional constraints on the study population in west-central Alberta, Canada. The models examined the proportion of macronutrients that bears could consume by mixing their diet from food available in each season, and assessed the extent to which bears could consume the ratio of protein to non-protein energy previously demonstrated using captive bears to optimize mass gain. We found that non-selective feeding on ungulate carcasses provided a non-optimal macronutrient balance with surplus protein relative to fat and carbohydrate, reflecting adaptation to an omnivorous lifestyle, and that optimization through feeding selectively on different tissues of ungulate carcasses is unlikely. Bears were, however, able to dilute protein intake to an optimal ratio by mixing their otherwise high-protein diet with carbohydrate-rich fruit. Some individual food items were close to optimally balanced in protein to non-protein energy (e.g. Hedysarum alpinum roots), which may help explain their dietary prevalence. Ants may be consumed particularly as a source of lipids. Overall, our analysis showed that most food available to bears in the study area were high in protein relative to lipid or carbohydrate, suggesting the lack of non-protein energy limits the fitness (e.g. body size and reproduction) and population density

  7. Dietary macronutrient content alters cortisol metabolism independently of body weight changes in obese men.

    Science.gov (United States)

    Stimson, Roland H; Johnstone, Alexandra M; Homer, Natalie Z M; Wake, Deborah J; Morton, Nicholas M; Andrew, Ruth; Lobley, Gerald E; Walker, Brian R

    2007-11-01

    Dietary macronutrient composition influences cardiometabolic health independently of obesity. Both dietary fat and insulin alter glucocorticoid metabolism in rodents and, acutely, in humans. However, whether longer-term differences in dietary macronutrients affect cortisol metabolism in humans and contribute to the tissue-specific dysregulation of cortisol metabolism in obesity is unknown. The objective of the study was to test the effects of dietary macronutrients on cortisol metabolism in obese men. The study consisted of two randomized, crossover studies. The study was conducted at a human nutrition unit. Participants included healthy obese men. INTERVENTIONS, OUTCOME MEASURES, AND RESULTS: Seventeen obese men received 4 wk ad libitum high fat-low carbohydrate (HF-LC) (66% fat, 4% carbohydrate) vs. moderate fat-moderate carbohydrate (MF-MC) diets (35% fat, 35% carbohydrate). Six obese men participated in a similar study with isocaloric feeding. Both HF-LC and MF-MC diets induced weight loss. During 9,11,12,12-[(2)H](4)-cortisol infusion, HF-LC but not MF-MC increased 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) activity (rates of appearance of cortisol and 9,12,12-[(2)H](3)-cortisol) and reduced urinary excretion of 5alpha- and 5beta-reduced [(2)H](4)-cortisol metabolites and [(2)H](4)-cortisol clearance. HF-LC also reduced 24-h urinary 5alpha- and 5beta-reduced endogenous cortisol metabolites but did not alter plasma cortisol or diurnal salivary cortisol rhythm. In sc abdominal adipose tissue, 11beta-HSD1 mRNA and activity were unaffected by diet. A low-carbohydrate diet alters cortisol metabolism independently of weight loss. In obese men, this enhances cortisol regeneration by 11beta-HSD1 and reduces cortisol inactivation by A-ring reductases in liver without affecting sc adipose 11beta-HSD1. Alterations in cortisol metabolism may be a consequence of macronutrient dietary content and may mediate effects of diet on metabolic health.

  8. Nitrogen and potassium fertilization in yield and macronutrients contents of heliconia cv. Golden Torch

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    Márkilla Z. Beckmann-Cavalcante

    2016-04-01

    Full Text Available ABSTRACT This study aimed to evaluate the effect of nitrogen (N and potassium (K fertilization in yield and contents of macronutrients in heliconia plants (Heliconia psittacorum x Heliconia spathocircinata Aristeguieta cv. Golden Torch. The experiment was set in a randomized block design, in a 4 x 4 factorial, corresponding to N doses (0, 120, 180 and 240 g of N hole-1 and K doses (0, 120, 180 and 240 g of K2O hole-1 with four replicates and five rhizomes per plot, under field conditions. After one year of cultivation, yield (number of flower stems per square meter and the leaf contents of N, P, K, Ca, Mg and S were determined. The applied N doses did not influence either yield or the leaf contents of the evaluated macronutrients. K fertilization favored the increase in leaf K content and the decrease in the contents of P, Ca and Mg in leaves of heliconias. Under the conditions of this experiment, it is recommended to apply 161.46 g of K2O hole-1 for a maximum yield of 9.89 stems m-2 per month.

  9. Macronutrient Balance and Dietary Glycemic Index in Pregnancy Predict Neonatal Body Composition

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    Nathalie V. Kizirian

    2016-05-01

    Full Text Available The influence of maternal macronutrient balance and dietary glycemic index (GI on neonatal body composition has received little study. We hypothesized that the overall quantity and quality of macronutrients, particularly carbohydrate, in the maternal diet could have trimester-specific effects on neonatal growth and body composition in women at risk of gestational diabetes. Maternal diet was assessed using 3-day food records in mid (n = 96 and late (n = 88 pregnancy as part of the GI Baby 3 study. Neonatal body composition was assessed by air-displacement plethysmography within 48 h of birth, adjusted for length, and expressed as fat mass index (FMI and fat-free mass index (FFMI. In mid pregnancy, higher maternal intake of carbohydrate energy was negatively correlated with infant FFMI (p = 0.037. In late pregnancy, higher dietary GI was associated with lower FFMI (p = 0.010 and higher carbohydrate energy predicted lower FMI (p = 0.034. Higher fat intake (%E and saturated fat, but not protein, also predicted neonatal body composition (higher FFMI in mid pregnancy and higher FMI in late pregnancy. Depending on pregnancy stage, a high carbohydrate-low fat diet, particularly from high glycemic sources, may reduce neonatal indices of both lean mass and adiposity.

  10. The association between dietary macronutrient intake and the prevalence of the metabolic syndrome.

    Science.gov (United States)

    Skilton, Michael R; Laville, Martine; Cust, Anne E; Moulin, Philippe; Bonnet, Fabrice

    2008-08-01

    We examined the association of dietary carbohydrates, protein, fat (including fatty acid subtypes) and alcohol with the metabolic syndrome and its components, in a cross-sectional study of 1626 patients with at least one cardiovascular risk factor. Multivariate nutrient density substitution models were used to examine the associations between macronutrients (assessed by 24 h dietary recall) and the metabolic syndrome. These models express the effects of 'substituting' one macronutrient for another without altering total energy intake. Increases in carbohydrates offset by isoenergetic decreases in either fat or protein were associated with a decrease in the prevalence of the metabolic syndrome (OR 0.87 (95 % CI 0.81, 0.93), P 0.10). Consumption of up to one standard alcoholic drink per d was associated with a lower prevalence of the metabolic syndrome when compared with non-drinkers (OR 0.67 (95 % CI 0.50, 0.89), P = 0.006); however, these benefits were weakened with higher levels of alcohol intake (P = 0.10 for one to three drinks and P = 0.29 for >three drinks). Thus, a diet high in carbohydrates, low in fat and protein, with low-to-moderate alcohol intake, is associated with a reduced prevalence of the metabolic syndrome.

  11. Macronutrient Distribution and Dietary Sources in the Spanish Population: Findings from the ANIBES Study

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    Emma Ruiz

    2016-03-01

    Full Text Available Our aim was to analyze dietary macronutrient intake and its main sources according to sex and age. Results were derived from the ANIBES (“Anthropometry, Intake and Energy Balance in Spain” cross-sectional study using a nationally-representative sample of the Spanish population (9–75 years old. Mean dietary protein intake was 74.5 ± 22.4 g/day, with meat and meat products as the main sources (33.0%. Mean carbohydrate intake was 185.4 ± 60.9 g/day and was higher in children and adolescents; grains (49%, mainly bread, were the main contributor. Milk and dairy products (23% ranked first for sugar intake. Mean lipid intake was 78.1 ± 26.1 g/day and was higher in younger age groups; contributions were mainly from oils and fats (32.5%; olive oil 25.6% and meat and meat products (22.0%. Lipid profiles showed relatively high monounsaturated fatty acid intake, of which olive oil contributed 38.8%. Saturated fatty acids were mainly (>70% combined from meat and meat products, milk and dairy products and oils and fats. Polyunsaturated fatty acids were mainly from oils and fats (31.5%. The macronutrient intake and distribution in the Spanish population is far from population reference intakes and nutritional goals, especially for children and adolescents.

  12. Macronutrient Distribution and Dietary Sources in the Spanish Population: Findings from the ANIBES Study

    Science.gov (United States)

    Ruiz, Emma; Ávila, José Manuel; Valero, Teresa; del Pozo, Susana; Rodriguez, Paula; Aranceta-Bartrina, Javier; Gil, Ángel; González-Gross, Marcela; Ortega, Rosa M.; Serra-Majem, Lluis; Varela-Moreiras, Gregorio

    2016-01-01

    Our aim was to analyze dietary macronutrient intake and its main sources according to sex and age. Results were derived from the ANIBES (“Anthropometry, Intake and Energy Balance in Spain”) cross-sectional study using a nationally-representative sample of the Spanish population (9–75 years old). Mean dietary protein intake was 74.5 ± 22.4 g/day, with meat and meat products as the main sources (33.0%). Mean carbohydrate intake was 185.4 ± 60.9 g/day and was higher in children and adolescents; grains (49%), mainly bread, were the main contributor. Milk and dairy products (23%) ranked first for sugar intake. Mean lipid intake was 78.1 ± 26.1 g/day and was higher in younger age groups; contributions were mainly from oils and fats (32.5%; olive oil 25.6%) and meat and meat products (22.0%). Lipid profiles showed relatively high monounsaturated fatty acid intake, of which olive oil contributed 38.8%. Saturated fatty acids were mainly (>70%) combined from meat and meat products, milk and dairy products and oils and fats. Polyunsaturated fatty acids were mainly from oils and fats (31.5%). The macronutrient intake and distribution in the Spanish population is far from population reference intakes and nutritional goals, especially for children and adolescents. PMID:27011202

  13. Macronutrient Balance and Dietary Glycemic Index in Pregnancy Predict Neonatal Body Composition

    Science.gov (United States)

    Kizirian, Nathalie V.; Markovic, Tania P.; Muirhead, Roslyn; Brodie, Shannon; Garnett, Sarah P.; Louie, Jimmy C. Y.; Petocz, Peter; Ross, Glynis P.; Brand-Miller, Jennie C.

    2016-01-01

    The influence of maternal macronutrient balance and dietary glycemic index (GI) on neonatal body composition has received little study. We hypothesized that the overall quantity and quality of macronutrients, particularly carbohydrate, in the maternal diet could have trimester-specific effects on neonatal growth and body composition in women at risk of gestational diabetes. Maternal diet was assessed using 3-day food records in mid (n = 96) and late (n = 88) pregnancy as part of the GI Baby 3 study. Neonatal body composition was assessed by air-displacement plethysmography within 48 h of birth, adjusted for length, and expressed as fat mass index (FMI) and fat-free mass index (FFMI). In mid pregnancy, higher maternal intake of carbohydrate energy was negatively correlated with infant FFMI (p = 0.037). In late pregnancy, higher dietary GI was associated with lower FFMI (p = 0.010) and higher carbohydrate energy predicted lower FMI (p = 0.034). Higher fat intake (%E) and saturated fat, but not protein, also predicted neonatal body composition (higher FFMI in mid pregnancy and higher FMI in late pregnancy). Depending on pregnancy stage, a high carbohydrate-low fat diet, particularly from high glycemic sources, may reduce neonatal indices of both lean mass and adiposity. PMID:27164136

  14. Interactions between accumulation of trace elements and macronutrients in Salix caprea after inoculation with rhizosphere microorganisms.

    Science.gov (United States)

    De Maria, Susanna; Rivelli, Anna R; Kuffner, Melanie; Sessitsch, Angela; Wenzel, Walter W; Gorfer, Markus; Strauss, Joseph; Puschenreiter, Markus

    2011-08-01

    Although the beneficial effects on growth and trace element accumulation in Salix spp. inoculated with microbes are well known, little information is available on the interactions among trace elements and macronutrients. The main purpose of this study was to assess the effect of phytoaugmentation with the rhizobacteria Agromyces sp., Streptomyces sp., and the combination of each of them with the fungus Cadophora finlandica on biomass production and the accumulation of selected trace elements (Zn, Cd, Fe) and macronutrients (Ca, K, P and Mg) in Salix caprea grown on a moderately polluted soil. Dry matter production was significantly enhanced only upon inoculation with Agromyces sp. Regarding the phytoextraction of Cd and Zn, shoot concentrations were mostly increased after inoculation with Streptomyces sp. and Agromyces sp. + C. finlandica. These two treatments also showed higher translocation factors from roots to the leaves for both Cd and Zn. The accumulation of Cd and Zn in shoots was related to increased concentrations of K. This suggests that microorganisms that contribute to enhanced phytoextraction of Cd and Zn affect also the solubility and thus phytoavailability of K. This study suggests that the phytoextraction of Zn and Cd can be improved by inoculation with selected microbial strains. Copyright © 2011 Elsevier Ltd. All rights reserved.

  15. Antioxidant enzymatic defenses and oxidative damage in Dentex dentex fed on different dietary macronutrient levels.

    Science.gov (United States)

    Pérez-Jiménez, Amalia; Hidalgo, M Carmen; Morales, Amalia E; Arizcun, Marta; Abellán, Emilia; Cardenete, Gabriel

    2009-11-01

    A wide range of antioxidant mechanisms are present in fish maintaining an adequate "oxidative balance". When this balance tilts in favor of the oxidant agents "oxidative stress" arises with detrimental effects in molecules of great biological importance. Little has been reported about the influence of different dietary energy sources on antioxidant defenses in fish. The influence of different dietary macronutrient combinations on the key antioxidant enzyme activity, the oxidative damage to lipids and proteins and the possible modifications in the SOD isoenzymatic pattern were evaluated in liver, white muscle, heart and erythrocytes of common dentex (Dentex dentex). Four experimental diets with different protein:lipid:carbohydrate ratios (43/16/28; 43/24/4; 38/19/28 and 38/24/13) were formulated. In general, neither different dietary macronutrient levels nor the interaction among them induces substantial modifications in enzymatic antioxidant defense mechanisms. Two constitutive SOD isoforms, CuZn-SOD I and Mn-SOD, were detected in the tissues analyzed in all experimental groups, independently of diet formulation, but, a third SOD isoenzyme, CuZn-SOD II seems to be induced in white muscle by higher dietary protein levels. Densitometric analyses of western blotting membranes revealed higher CuZn-SOD expression in the heart of dentex fed on lower dietary protein levels, although these differences did not correlate with the SOD activity. Finally, a direct relation exists between the lipid or protein intake level and occurrence of oxidative damage in different tissue components.

  16. Validation of an in vitro digestive system for studying macronutrient decomposition in humans.

    Science.gov (United States)

    Kopf-Bolanz, Katrin A; Schwander, Flurina; Gijs, Martin; Vergères, Guy; Portmann, Reto; Egger, Lotti

    2012-02-01

    The digestive process transforms nutrients and bioactive compounds contained in food to physiologically active compounds. In vitro digestion systems have proven to be powerful tools for understanding and monitoring the complex transformation processes that take place during digestion. Moreover, the investigation of the physiological effects of certain nutrients demands an in vitro digestive process that is close to human physiology. In this study, human digestion was simulated with a 3-step in vitro process that was validated in depth by choosing pasteurized milk as an example of a complex food matrix. The evolution and decomposition of the macronutrients was followed over the entire digestive process to the level of intestinal enterocyte action, using protein and peptide analysis by SDS-PAGE, reversed-phase HPLC, size exclusion HPLC, and liquid chromatography-MS. The mean peptide size after in vitro digestion of pasteurized milk was 5-6 amino acids (AA). Interestingly, mostly essential AA (93.6%) were released during in vitro milk digestion, a significantly different relative distribution compared to the total essential AA concentration of bovine milk (44.5%). All TG were degraded to FFA and monoacylglycerols. Herein, we present a human in vitro digestion model validated for its ability to degrade the macronutrients of dairy products comparable to physiological ranges. It is suited to be used in combination with a human intestinal cell culture system, allowing ex vivo bioavailability measurements and assessment of the bioactive properties of food components.

  17. Genetic mapping of QTLs associated with seed macronutrients accumulation in 'MD96-5722' by 'Spencer' recombinant inbred lines of soybean

    Science.gov (United States)

    Research of genetic mapping of QTLs for macronutrient accumulation in soybean seed is limited. Therefore, the objective of this research was to identify QTLs related to macronutrients (N, C, S, P, K, Ca, and Mg) in seeds in 92 F5:7 recombinant inbred lines developed from a cross between MD 96-5722 (...

  18. Effects of different phosphorus and potassium fertilization on contents and uptake of macronutrients (N, P, K, Ca, Mg in winter wheat I. Content of macronutrients

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    Renata GAJ

    2014-12-01

    Full Text Available The aim of the study carried out under field conditions was to evaluate the effect of differentiated phosphorus and potassium fertilization level on nutritional status of winter wheat at stem elongation (BBCH 31 and flowering (BBCH 65 development stages as well as on macronutrient contents in yield obtained (grain and straw. The research was conducted in 2007-2010, within an individual agricultural holding, on lessive soil with medium and high richness in potassium and phosphorus, respectively. The contents of nitrogen, phosphorus, potassium, magnesium and calcium in wheat changed depending on the organ assessed and plant development stage. At BBCH 31, regardless fertilization level, the plants observed were malnourished with potassium, phosphorus and calcium and at the control site also with nitrogen. Furthermore, there were found significant correlation relationships among the contents of nutrient pairs: nitrogen-potassium, nitrogen-phosphorus, nitrogen-magnesium and nitrogen-calcium. The content of nitrogen in wheat grain and straw differed mainly due to weather conditions during the study. Irrespective of the years of observation, differentiated rates of P and K applied had no significant effect on N accumulation in wheat at full ripening stage. In contrast to nitrogen, the level of P and K fertilization significantly differentiated the contents of phosphorus, potassium and magnesium in wheat grain and straw. In case of calcium, the effect of fertilization factor was indicated only as regards the content of this nutrient in grain.

  19. Lipid-Based Nutrient Supplements Increase Energy and Macronutrient Intakes from Complementary Food among Malawian Infants.

    Science.gov (United States)

    Hemsworth, Jaimie; Kumwenda, Chiza; Arimond, Mary; Maleta, Kenneth; Phuka, John; Rehman, Andrea M; Vosti, Stephen A; Ashorn, Ulla; Filteau, Suzanne; Dewey, Kathryn G; Ashorn, Per; Ferguson, Elaine L

    2016-02-01

    Low intakes of good-quality complementary foods (CFs) contribute to undernutrition and consequently negatively affect health, growth, and development. Lipid-based nutrient supplements (LNSs) are designed to ensure dietary adequacy in micronutrients and essential fatty acids and to provide some energy and high-quality protein. In populations in which acute energy deficiency is rare, the dose-dependent effect of LNSs on CF intakes is unknown. The objective of this study was to evaluate the difference in energy and macronutrient intakes from CF between a control (no supplement) group and 3 groups that received 10, 20, or 40 g LNS/d. We collected repeated interactive 24-h dietary recalls from caregivers of rural Malawian 9- to 10-mo-old infants (n = 748) to estimate dietary intakes (LNS and all non-breast-milk foods) of energy and macronutrients and their dietary patterns. All infants were participating in a 12-mo randomized controlled trial to investigate the efficacy of various doses of LNS for preventing undernutrition. Dietary energy intakes were significantly higher among infants in the LNS intervention groups than in the control group (396, 406, and 388 kcal/d in the 10-, 20-, and 40-g LNS/d groups, respectively, compared with 345 kcal/d; each pairwise P energy intakes between groups who were administered the different LNS doses (10 g LNS/d compared with 20 g LNS/d: P = 0.72; 10 g LNS/d compared with 40 g LNS/d: P ≥ 0.67; 20 g LNS/d compared with 40 g LNS/d: P = 0.94). Intakes of protein and fat were significantly higher in the LNS intervention groups than in the control group. No significant intergroup differences were found in median intakes of energy from non-LNS CFs (357, 347, and 296 kcal/d in the 10-, 20-, and 40-g LNS/d groups, respectively, compared with 345 kcal/d in the control group; P = 0.11). LNSs in doses of 10-40 g/d increase intakes of energy and macronutrients among 9- to 10-mo-old Malawian infants, without displacing locally available CFs

  20. Comparing dietary macronutrient composition and food sources between native and diasporic Ghanaian adults

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    Rachel Gibson

    2015-11-01

    Full Text Available Background: Dietary acculturation may contribute to the increased burden of non-communicable diseases (NCDs in diasporic populations of African ancestry. Objective: To assess nutritional composition and the contribution that traditional foods make to the diets of native and UK-dwelling Ghanaian adults. Design: An observational study of Ghanaian adults living in Accra (n=26 and London (n=57 was undertaken. Three-day food records were translated to nutrient data using culturally sensitive methods and comparisons were made for energy, macronutrients, and dietary fibre between cohorts. The contribution of traditional foods to dietary intake was measured and the foods contributing to each nutrient were identified. Results: Compared to native Ghanaians, UK-Ghanaians derived a significantly higher proportion of energy from protein (16.9±3.9 vs. 14.1±2.8%, p=0.001, fat (29.9±7.9 vs. 24.4±8.5%, p=0.005, and saturated fat (8.5±3.4 vs. 5.8±3.7%, p<0.001 and a significantly lower energy from carbohydrate (52.2±7.7 vs. 61.5±9.3%, p<0.001. Dietary fibre intake was significantly higher in the UK-Ghanaian diet compared to the native Ghanaian diet (8.3±3.1 vs. 6.7±2.2 g/1,000 kcal, p=0.007. There was significantly less energy, macronutrients, and fibre derived from traditional foods post-migration. Non-traditional foods including breakfast cereals, wholemeal bread, and processed meats made a greater contribution to nutrient intake post-migration. Conclusions: Our findings show the migrant Ghanaian diet is characterised by significantly higher intakes of fat, saturated fat, and protein and significantly lower intakes of carbohydrate; a macronutrient profile which may promote increased risk of NCDs amongst UK-Ghanaians. These differences in the nutrient profile are likely to be modulated by the consumption of ‘Western’ foods observed in migrant communities.

  1. Nutrient extraction and exportation by common bean cultivars under different fertilization levels: I - macronutrients

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    Rogério Peres Soratto

    2013-08-01

    Full Text Available The use of cultivars with a higher yield potential and the adoption of new technology have achieved high grain yields in common bean, which probably changed the demand for nutrients in this crop. However, there is almost no information about the periods of the cycle in which nutrients are most demanded at which quantities by the main cultivars. The objective of this study was to evaluate the macronutrient extraction and exportation by the common bean cultivars Pérola and IAC Alvorada, under different levels of NPK fertilization, on a dystroferric Red Nitosol, in Botucatu, São Paulo State, Brazil. The experiment was arranged in a randomized complete block (split plot design with four replications. The plots consisted of six treatments based on a 2 x 3 factorial model, represented by two cultivars and three NPK levels (PD0 - 'Pérola' without fertilization, PD1 - 'Pérola' with 50 % of recommended fertilization, PD2 - 'Pérola' with 100 % of recommended fertilization, AD0 - 'IAC Alvorada' without fertilization, AD1 - 'IAC Alvorada' with 50 % of recommended fertilization, and AD2 - 'IAC Alvorada' with 100 % of recommended fertilization and subplots sampled seven times during the cycle. At higher levels of NPK fertilization, the grain yield and macronutrient extraction and exportation of both cultivars were higher, but without statistical differences. Macronutrient absorption was higher in the treatments with 100 % of recommended NPK fertilization (average amounts per hectare: 140 kg N, 16.5 kg P, 120 kg K, 69 kg Ca, 17.9 kg Mg, and 16.3 kg S. Regardless of the treatment, the demand for N, P, K, Ca, and Mg was highest from 45 to 55 days after emergence (DAE, i.e., in the R7 stage (pod formation, while the highest S absorption rates were concentrated between 55 and 65 DAE. More than 70 % of P, between 58 and 69 % of N, 40 and 52 % of S, 40 and 48 % of K, and 35 and 45 % of Mg absorbed during the cycle was exported with grains, whereas less than 15

  2. Macronutrient Composition of the Diet and Prospective Weight Change in Participants of the EPIC-PANACEA Study

    NARCIS (Netherlands)

    Vergnaud, Anne-Claire; Norat, Teresa; Mouw, Traci; Romaguera, Dora; May, Anne M.; Bueno-de-Mesquita, H. Bas; van der Daphne, A.; Agudo, Antonio; Wareham, Nicholas; Khaw, Kay-Tee; Romieu, Isabelle; Freisling, Heinz; Slimani, Nadia; Perquier, Florence; Boutron-Ruault, Marie-Christine; Clavel-Chapelon, Francoise; Palli, Domenico; Berrino, Franco; Mattiello, Amalia; Tumino, Rosario; Ricceri, Fulvio; Rodriguez, Laudina; Molina-Montes, Esther; Amiano, Pilar; Barricarte, Aurelio; Chirlaque, Maria-Dolores; Crowe, Francesca L.; Orfanos, Philippos; Naska, Androniki; Trichopoulou, Antonia; Teucher, Birgit; Kaaks, Rudolf; Boeing, Heiner; Buijsse, Brian; Johansson, Ingeged; Hallmans, Goran; Drake, Isabel; Sonestedt, Emily; Jakobsen, Marianne Uhre; Overvad, Kim; Tjonneland, Anne; Halkjaer, Jytte; Skeie, Guri; Braaten, Tonje; Lund, Eiliv; Riboli, Elio; Peeters, Petra H. M.

    2013-01-01

    Background: The effect of the macronutrient composition of the usual diet on long term weight maintenance remains controversial. Methods: 373,803 subjects aged 25-70 years were recruited in 10 European countries (1992-2000) in the PANACEA project of the EPIC cohort. Diet was assessed at baseline usi

  3. Energy and macronutrient intake and risk of differentiated thyroid carcinoma in the European Prospective Investigation into Cancer and Nutrition study

    NARCIS (Netherlands)

    Zamora-Ros, Raul; Rinaldi, Sabina; Tsilidis, Konstantinos K.; Weiderpass, Elisabete; Boutron-Ruault, Marie Christine; Rostgaard-Hansen, Agnetha Linn; Tjønneland, Anne; Clavel-Chapelon, Françoise; Mesrine, Sylvie; Katzke, Verena A.; Kühn, Tilman; Förster, Jana; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Klinaki, Eleni; Masala, Giovanna; Sieri, Sabina; Ricceri, Fulvio; Tumino, Rosario; Mattiello, Amalia; Peeters, Petra H M; Bueno-De-Mesquita, H. B.; Engeset, Dagrun; Skeie, Guri; Argüelles, Marcial; Agudo, Antonio; Sánchez, María José; Chirlaque, María Dolores; Barricarte, Aurelio; Chamosa, Saioa; Almquist, Martin; Tosovic, Ada; Hennings, Joakim; Sandström, Maria; Schmidt, Julie A.; Khaw, Kay Thee; Wareham, Nicholas J.; Cross, Amanda J.; Slimani, Nadia; Byrnes, Graham; Romieu, Isabelle; Riboli, Elio; Franceschi, Silvia

    2016-01-01

    Incidence rates of differentiated thyroid carcinoma (TC) have increased in many countries. Adiposity and dietary risk factors may play a role, but little is known on the influence of energy intake and macronutrient composition. The aim of this study was to investigate the associations between TC and

  4. Macronutrient intake and risk of urothelial cell carcinoma in the European prospective investigation into cancer and nutrition

    NARCIS (Netherlands)

    Allen, N.E.; Appleby, P.N.; Key, T.J.; Bueno-De-Mesquita, H.B.; Ros, M.M.; Kiemeney, L.A.L.M.; Tjonneland, A.; Roswall, N.; Overvad, K.; Weikert, S.; Boeing, H.; Chang-Claude, J.; Teucher, B.; Panico, S.; Sacerdote, C.; Tumino, R.; Palli, D.; Sieri, S.; Peeters, P.; Quiros, J.R.; Jakszyn, P.; Molina-Montes, E.; Chirlaque, M.D.; Ardanaz, E.; Dorronsoro, M.; Khaw, K.T.; Wareham, N.; Ljungberg, B.; Hallmans, G.; Ehrnstrom, R.; Ericson, U.; Gram, I.T.; Parr, C.L.; Trichopoulou, A.; Karapetyan, T.; Dilis, V.; Clavel-Chapelon, F.; Boutron-Ruault, M.C.; Fagherrazzi, G.; Romieu, I.; Gunter, M.J.; Riboli, E.

    2013-01-01

    Previous studies have suggested that dietary factors may be important in the development of bladder cancer. We examined macronutrient intake in relation to risk of urothelial cell carcinoma among 469,339 men and women in the European Prospective Investigation into Cancer and Nutrition. Associations

  5. Phosphate Rock Application on Alfalfa (Medicago sativa L. Production and Macronutrients in Latosol Soil

    Directory of Open Access Journals (Sweden)

    Y. Liani

    2011-12-01

    Full Text Available The objective of this study was to evaluate the effectiveness of phosphate rocks (PRs fertilizer compared to chemical P fertilizer for the best crop production and macronutrients of alfalfa. A completely randomized design under 3x3 factorial patterns was used in this research. The first factor was different sources of P fertilizer: Guizhou Phosphate Rock (GPR, Jingxiang Phosphate Rock (JPR, and Single Super Phosphate (SSP. The second factor was level of P fertilizer: 75, 100, and 125 mg P2O5/kg soil. A control treatment (without addition of P fertilizer, CK was added as a comparison with the treatments. The results showed that JPR was the best for alfalfa production, whereas GPR and SSP were better for nutrient content in the alfalfa tissue than JPR. On the whole, phosphate rocks had similar effect on alfalfa growth compared to SSP at the experimental conditions.

  6. Macronutrients and Health—Steps to Ameliorating the Nutrition transition Trap

    Institute of Scientific and Technical Information of China (English)

    D.C.K.ROBERTS

    2001-01-01

    Countries that have made the health transition from a communicable disease base to a non-communicable disease base find themselves gripped in an epidemic of wealth created diseases mediated by altered macronutrient intakes,energy intakes and reduction in physical activity.Avoiding the negative impact of the nutrition transition while accepting the positive aspects of the wealth transition can best be achieved by focussing on publicising the benefits of a low fat diet in the context of an active lifestyle.How this is achieved should reflect ecologically sound food production appropriate to national needs.Countries that achieve this will be in the best position to capitalize on the reduction in communicable disease rates without causing a rise in non-communicalble disease rates.

  7. Macronutrients and Health—Steps to Ameliorating the Nutrition Transition Trap

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Countries that have made the health transition from acommunicable disease base to a non-communicable disease base find themselves gripped in an epidemic of wealth created diseases mediated by altered macronutrient intakes, energy intakes and reduction in physical activity. Avoiding the negative impact of the nutrition transition while accepting the positive aspects of the wealth transition can best be achieved by focussing on publicising the benefits of a low fat diet in the context of an active lifestyle. How this is achieved should reflect ecologically sound food production appropriate to national needs. Countries that achieve this will be in the best position to capitalize on the reduction in communicable disease rates without causing a rise in non-communicable disease rates.

  8. Quantitative determination of the human breast milk macronutrients by near-infrared Raman spectroscopy

    Science.gov (United States)

    Motta, Edlene d. C. M.; Zângaro, Renato A.; Silveira, Landulfo, Jr.

    2012-03-01

    This work proposes the evaluation of the macronutrient constitution of human breast milk based on the spectral information provided by near-infrared Raman spectroscopy. Human breast milk (5 mL) from a subject was collected during the first two weeks of breastfeeding and stocked in -20°C freezer. Raman spectra were measured using a Raman spectrometer (830 nm excitation) coupled to a fiber based Raman probe. Spectra of human milk were dominated by bands of proteins, lipids and carbohydrates in the 600-1800 cm-1 spectral region. Raman spectroscopy revealed differences in the biochemical constitution of human milk depending on the time of breastfeeding startup. This technique could be employed to develop a classification routine for the milk in Human Milk Banking (HMB) depending on the nutritional facts.

  9. Dietary patterns, food and macronutrient intakes among adults in three ethnic groups in rural Kenya

    DEFF Research Database (Denmark)

    Hansen, Andreas Wolff; Christensen, Dirk; Larsson, Melanie

    2011-01-01

    Objective. To compare dietary patterns and food and macronutrient intakes among adults in three ethnic groups in rural Kenya. Design. In the present cross-sectional study, dietary intake was estimated in adult volunteers using two non-consecutive interactive 24 h recalls. Dietary patterns were...... was conducted in the Bondo, Kitui and Transmara districts of rural Kenya. A high prevalence of food insecurity in Kenya underlines the importance of describing the dietary patterns and intakes in different Kenyan ethnic groups. Subjects. A total of 1163 (61% women) adult Luo, Kamba and Maasai, with a mean age...... of 38.6 (range: 18–68) years, volunteered to participate. Results. Dietary patterns and food groups contributing to EI differed significantly among the ethnic groups. Mean EI ranged from 5.8 to 8.6 MJ/d among women and from 7.2 to 10.5 MJ/d among men, with carbohydrates contributing between 55.7% and 74...

  10. Comparing dietary macronutrient composition and food sources between native and diasporic Ghanaian adults

    Science.gov (United States)

    Gibson, Rachel; Knight, Annemarie; Asante, Matilda; Thomas, Jane; Goff, Louise M.

    2015-01-01

    Background Dietary acculturation may contribute to the increased burden of non-communicable diseases (NCDs) in diasporic populations of African ancestry. Objective To assess nutritional composition and the contribution that traditional foods make to the diets of native and UK-dwelling Ghanaian adults. Design An observational study of Ghanaian adults living in Accra (n=26) and London (n=57) was undertaken. Three-day food records were translated to nutrient data using culturally sensitive methods and comparisons were made for energy, macronutrients, and dietary fibre between cohorts. The contribution of traditional foods to dietary intake was measured and the foods contributing to each nutrient were identified. Results Compared to native Ghanaians, UK-Ghanaians derived a significantly higher proportion of energy from protein (16.9±3.9 vs. 14.1±2.8%, p=0.001), fat (29.9±7.9 vs. 24.4±8.5%, p=0.005), and saturated fat (8.5±3.4 vs. 5.8±3.7%, pwholemeal bread, and processed meats made a greater contribution to nutrient intake post-migration. Conclusions Our findings show the migrant Ghanaian diet is characterised by significantly higher intakes of fat, saturated fat, and protein and significantly lower intakes of carbohydrate; a macronutrient profile which may promote increased risk of NCDs amongst UK-Ghanaians. These differences in the nutrient profile are likely to be modulated by the consumption of ‘Western’ foods observed in migrant communities. PMID:26610275

  11. Macronutrient composition determines accumulation of persistent organic pollutants from dietary exposure in adipose tissue of mice.

    Science.gov (United States)

    Myrmel, Lene Secher; Fjære, Even; Midtbø, Lisa Kolden; Bernhard, Annette; Petersen, Rasmus Koefoed; Sonne, Si Brask; Mortensen, Alicja; Hao, Qin; Brattelid, Trond; Liaset, Bjørn; Kristiansen, Karsten; Madsen, Lise

    2016-01-01

    Accumulation of persistent organic pollutants (POPs) has been linked to adipose tissue expansion. As different nutrients modulate adipose tissue development, we investigated the influence of dietary composition on POP accumulation, obesity development and related disorders. Lifespan was determined in mice fed fish-oil-based high fat diets during a long-term feeding trial and accumulation of POPs was measured after 3, 6 and 18months of feeding. Further, we performed dose-response experiments using four abundant POPs found in marine sources, PCB-153, PCB-138, PCB-118 and pp'-DDE as single congeners or as mixtures in combination with different diets: one low fat diet and two high fat diets with different protein:sucrose ratios. We measured accumulation of POPs in adipose tissue and liver and determined obesity development, glucose tolerance, insulin sensitivity and hepatic expression of genes involved in metabolism of xenobiotics. Compared with mice fed diets with a low protein:sucrose ratio, mice fed diets with a high protein:sucrose ratio had significantly lower total burden of POPs in adipose tissue, were protected from obesity development and exhibited enhanced hepatic expression of genes involved in metabolism and elimination of xenobiotics. Exposure to POPs, either as single compounds or mixtures, had no effect on obesity development, glucose tolerance or insulin sensitivity. In conclusion, this study demonstrates that the dietary composition of macronutrients profoundly modulates POP accumulation in adipose tissues adding an additional parameter to be included in future studies. Our results indicate that alterations in macronutrient composition might be an additional route for reducing total body burden of POPs. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Energy and macronutrient intakes in preschool children in urban areas of Ho Chi Minh City, Vietnam

    Directory of Open Access Journals (Sweden)

    Sibbritt David W

    2008-10-01

    Full Text Available Abstract Background An increasing prevalence of overweight and obesity has been documented in preschool children in Ho Chi Minh City (HCMC, Vietnam. However, little is known about what preschool children in HCMC eat or how well their nutrient intake meets nutrient recommendations. This study aims to describe the energy and macronutrient intake and compare these nutrient intakes with the recommendations for Vietnamese children aged four to five years. Methods The data comes from the baseline measurement of a one year follow-up study on obesity in 670 children attending kindergartens in HCMC. Dietary information for each child at the school and home settings was collected using Food Frequency Questionnaires (FFQs, by interviewing teachers and parents or main caregivers. The average energy and nutrient intake in a day was calculated. The proportion of children with energy intake from macronutrients meeting or exceeding the recommendations was estimated based on the 2006 recommended daily allowance (RDA for Vietnamese children in this age group. Results The dietary intake of the participants contained more energy from protein and fat, particularly animal protein and fat, and less energy from carbohydrates, than the RDA. Most children (98.1% had mean energy intake from protein greater than the recommended level of 15%, and no child obtained energy from animal fat that was in accordance with the recommendation of less than 30% of the total fat intake. Nearly one half of children (46.5% consumed less than the advised range of mean energy intake from carbohydrate (60%–70%. Conclusion In this preschool child population in HCMC, in which obesity is emerging as major public health problem, there is an imbalance in dietary intake. Healthy eating programs need to be developed as a part of an obesity prevention program for young children in HCMC.

  13. Macronutrients and trace metals in soil and food crops of Isfahan Province, Iran.

    Science.gov (United States)

    Keshavarzi, Behnam; Moore, Farid; Ansari, Maryam; Rastegari Mehr, Meisam; Kaabi, Helena; Kermani, Maryam

    2015-01-01

    The distribution of 10 macronutrients and trace metals in the arable soils of Isfahan Province, their phytoavailability, and associated health risks were investigated; 134 plant and 114 soil samples (from 114 crop fields) were collected and analyzed at harvesting time. Calculation of the soil pollution index (SPI) revealed that arable soil polluted by metals was more severe in the north and southwest of the study area. The results of cluster analysis indicated that Pb, Zn, and Cu share a similar origin from industries and traffic. The concentrations of macronutrients and trace metals in the sampled crops were found in the order of K > Ca > S > Mg > P and Fe > Mn > Zn > Cu > Pb, respectively, whereas calculation of the bioconcentration factor (BCF) indicated that the accumulation of the investigated elements in crops was generally in the order of S ≈ K > P > Mg > Ca and Zn > Cu > Mn > Pb > Fe, respectively. Thus, various parameters including crop species and the physical, chemical, and biological properties of soil also affected the bioavailability of the elements besides the total element contents in soil. Daily intake (DI) values of elements were lower than the recommended daily intake (RDI) levels in rice grains except for Fe and Mn, but for wheat grains, all elements displayed DI values higher than the RDI. Moreover, based on the hazard index (HI) values, inhabitants are experiencing a significant potential health risk solely due to the consumption of wheat and rice grains (particularly wheat grains). Mn health quotient (HQ) also indicated a high risk of Mn absorption for crop consumer inhabitants.

  14. Macronutrient intakes and cardio metabolic risk factors in high BMI African American children

    Directory of Open Access Journals (Sweden)

    Hudes Mark L

    2009-10-01

    Full Text Available Abstract Background The aim of this study was to evaluate the relationship between intakes of energy-providing macronutrients, and markers of cardio metabolic risk factors in high BMI African American (AA children. Methods A cross sectional analysis of a sample of 9-11 year old children (n = 80 with BMI greater then the 85th percentile. Fasting hematological and biochemical measurements, and blood pressure were measured as selected markers of cardio metabolic risk factors and their relationships to dietary intakes determined. Results After adjusting for gender, pubertal stage and waist circumference (WC, multivariate regression analysis showed that higher total energy intakes (when unadjusted for source of energy were associated with higher plasma concentrations of intermediate density lipoprotein cholesterol (IDL-C and very low density lipoprotein cholesterol (VLDL-C. Higher intakes of carbohydrate energy (fat and protein held constant were associated with higher IDL-C, VLDL-C, triglycerides (TG and homeostasis model assessment of insulin resistance (HOMA-IR. Higher intakes of fat (carbohydrate and protein held constant, however, were associated with lower IDL-C; and higher protein intakes (fat and carbohydrate held constant were associated with lower HOMA-IR. Conclusion The specific macronutrients that contribute energy are significantly associated with a wide range of cardio metabolic risk factors in high BMI AA children. Increases in carbohydrate energy were associated with undesirable effects including increases in several classes of plasma lipids and HOMA-IR. Increases in protein energy were associated with the desirable effect of reduced HOMA-IR, and fat energy intakes were associated with the desirable effect of reduced IDL-C. This analysis suggests that the effect of increased energy on risk of developing cardio metabolic risk factors is influenced by the source of that energy.

  15. Effects of Maize Residue Removal and Tillage on Soil Erosion, Carbon, and Macronutrient Dynamics

    Science.gov (United States)

    Beniston, J.; Shipitalo, M.; Lal, R.; Dayton, E. A.; Hopkins, D.; Jones, F. S.; Joynes, A.; Dungait, J.

    2013-12-01

    Erosion by water is a principal process of soil degradation in agricultural lands. Soil erosion influences the storage and fluxes of C and key macronutrients N and P in soil surface layers. No till (NT) crop management significantly reduces erosion on susceptible landscapes. The selective removal of crop residues for bio-energy production from no-till systems has been suggested as a secondary crop, but the effect of this practice on the conservation benefits of NT has not been quantified. Therefore, this study was initiated in spring 2012 to examine the effects of soil management practices on erosion and associated macronutrient fluxes on erodible soils subjected to a high intensity simulated rain storm at the North Appalachian Experimental Watershed (NAEW) in Coshocton, OH, U.S.A. The soil management practices evaluated included: long term no-till with 100% crop residue (NT100) , no-till with 50% crop reside (NT50), NT with complete crop residue removal (NT0), long term conventional tillage (CT), and long term no-tillage plots that were cultivated (TNT) with a rototiller before the rainfall application. A field rainfall simulator was utilized to apply rainfall at an intensity of 7 cm hr-1 to a 4 m2 area of each plot for 30 minutes. Total runoff from the NT0 plots (22.1 mm) was almost double compared with the NT 50% (13.3 mm), CT (12.8 mm) and TNT (12.8 mm) plots and was more than 5 times greater than the NT100 plots (4.4mm). CT and NT0 plots produced 40 (2.7 Mg ha-1) and 20 times (1.4 Mg ha-1) more soil loss, respectively, than NT100 plots (0.07 Mg ha-1). Tillage of the no-till (TNT) soil produced the largest sediment-bound fluxes of C and N, while sediment-bound P fluxes were largest in the CT soils. Natural abundance δ13C and δ15N values were distinct between eroded sediments and the source topsoils and suggested enhanced loss of older (>28 yrs) C residues in CT plots. All observations suggest NT management provides greater resilience to soils than CT during

  16. Effect of Dietary Polydextrose on Feces Consistency and Macronutrient Digestibility in Healthy Dogs

    Directory of Open Access Journals (Sweden)

    K. Vasupen

    2011-01-01

    Full Text Available Problem statement: There is evidence that the addition of 3% STA-LITE® polydextrose to a dry food reduces the clinical signs of osteoarthritis in dogs. For the application of polydextrose as functional ingredient of dog foods, information as to its impact on the acceptance of food, feces consistency, fecal odor and digestibility of macronutrients and minerals is required. Approach: A feeding experiment with 4×4 Latin square design was carried out with 12 adult, healthy Golden Retrievers. The experimental diets consisted of a commercial dry food to which either 0, 2, 4 or 8% polydextrose was added. During the last 5 days of each two-week feeding period, feces of individual dogs were collected quantitatively. Feces consistency and fecal odor were scored. Fecal pH, fecal Lactobacilli and the apparent digestibility of macronutrients and minerals were determined. Results: The various inclusion levels of polydextrose did not affect food acceptance and intake and did not induce changes in body weight. Polydextrose intake did not influence fecal odor and the amount of feces production. Feces consistency was significantly affected by polydextrose; feces became softer with increasing dose. The apparent digestibilities of dietary dry matter, crude protein, crude fat and ash were not significantly affected by polydextrose intake. The apparent digestibilities of crude fiber and nitrogen-free extract were increased by the addition of polydextrose to the diet. Apparent digestibility of polydextrose was calculated to be 92% of intake. The high apparent digestibility of polydextrose points at fermentation of this functional ingredient in the hindgut of dogs, but it was not associated with a further lowering of fecal pH and increase in fecal Lactobacilli. Apparent calcium and phosphorus absorption were not significantly affected by polydextrose intake. Conclusion: In the clinical trial on canine osteoarthritis, a polydextrose dose of 3% in a dry dog food was

  17. [Daily calorie and macronutrient consumption in girls of different somatotypes with different shares of body fat, muscle and bone components].

    Science.gov (United States)

    Fefelova, V V; Fefelova, Yu A; Koloskova, T P; Kazakova, T V; Sergeeva, E Yu

    2016-01-01

    211 practically healthy girls, the students of Krasnoyarsk Medical University in the ages of 16 to 20 years, have been examined. We determined their somatotypes (euriplastic, athletic, subathletic and stenoplastic) and body composition (fat, muscle, bone component). Actual nutrition in these subjects was studied by the method. of 24-hour nutrition recall involving foodstuffs models. Energy consumption in cohorts with different somatotypes did not differ from one another and ranged from 1880 to 2115 kilocalories per day, that corresponded to normal physiological needs in women of this age with the coefficient of physical activity as 1.4 (students). Only the intake of fat (% of calories) exceeded the performance standards. As for macronutrients, the majority of indicators of nutrient intake did not differ significantly among girls with different somatotype, except for fat intake in girls with athletic and stenoplastic somatotypes (psomatotypes (psomatotypes with statistically considerable, differences in both overall dimensions (body mass and length) and the ratios between fat, muscle and bone as somatic components. In general, macronutrient consumption did not show any differences as well. Thus, apart from the energy and macronutrient consumption, definite meaning within the process of the formation of body composition can belong to the characteristics of the changes following nutrition load on lipoid spectrum of blood serum as well 'as the peculiarities of the distribution of substrate flow among cell metabolic paths, appropriate of definite somatotypes.

  18. Micronutrient quality of weight-loss diets that focus on macronutrients: results from the A TO Z study123

    Science.gov (United States)

    Gardner, Christopher D; Kim, Soowon; Bersamin, Andrea; Dopler-Nelson, Mindy; Otten, Jennifer; Oelrich, Beibei; Cherin, Rise

    2010-01-01

    Background: Information on the micronutrient quality of alternative weight-loss diets is limited, despite the significant public health relevance. Objective: Micronutrient intake was compared between overweight or obese women randomly assigned to 4 popular diets that varied primarily in macronutrient distribution. Design: Dietary data were collected from women in the Atkins (n = 73), Zone (n = 73), LEARN (Lifestyle, Exercise, Attitudes, Relationships, Nutrition) (n = 73), and Ornish (n = 72) diet groups by using 3-d, unannounced 24-h recalls at baseline and after 8 wk of instruction. Nutrient intakes were compared between groups at 8 wk and within groups for 8-wk changes in risk of micronutrient inadequacy. Results: At 8 wk, significant differences were observed between groups for all macronutrients and for many micronutrients (P Zone group, the risk of inadequacy significantly decreased for vitamins A, E, K, and C (P diets that focus on macronutrient composition should attend to the overall quality of the diet, including the adequacy of micronutrient intakes. Concerning calorie-restricted diets, there may be a micronutrient advantage to diets providing moderately low carbohydrate amounts and that contain nutrient-dense foods. PMID:20573800

  19. Efeito da omissão de macronutrientes em sisal Macronutrients deficiency on sisal (Agave sisalana perr.

    Directory of Open Access Journals (Sweden)

    Antonio Luiz de Barbos Salgado

    1982-01-01

    Full Text Available Plantas de sisal (Agave sisalana Perr. foram cultivadas em casa de vegetação, em vasos contendo areia lavada e irrigados com solução nutritiva completa e com soluções nutritivas com a omissão de cada macronutriente. As plantas mostraram, na ausência de cada nutriente, os sintomas típicos de sua carência, relacionados com baixos teores do respectivo elemento nas folhas, e redução no seu crescimento e desenvolvimento.Sisal plants were cultivated in washed sand during twenty-one months. The plants were irrigated with complete nutrient solution and solutions with absence of each macronutrient (N, P, K, Ca, Mg e S. The plants, in the absence of each macronutrient, showed typical symptoms which were related to the low level of the respective element in the leaf. The growing of the leaves was reduced by the absence of the macronutrients.

  20. Does monosodium glutamate interact with macronutrient composition to influence subsequent appetite?

    Science.gov (United States)

    Masic, Una; Yeomans, Martin R

    2013-05-27

    The influence of flavour enhancers such as monosodium glutamate (MSG) on satiation and satiety is unclear, and the present study aimed to explore this by examining the effects consumption of soups varying in MSG (1% MSG added or no MSG) and macronutrient content (added carbohydrate, protein or control) had on appetite. 24 non-obese, low-restraint male participants consumed a fixed portion of soup and rated their appetite before, immediately after intake and at 15 minute intervals for 120 min post-ingestion across six sessions. Added MSG significantly increased flavour pleasantness and tended to result in a smaller decrease in hunger immediately after soup ingestion. MSG also reduced rather than enhanced feelings of fullness immediately after ingestion of the high protein soup. As expected, hunger increased, and fullness decreased, over the subsequent 120 min, but the increase in hunger was significantly lower in the MSG than no-MSG conditions with the protein soup between 30 and 60 min post-ingestion. Overall these data suggest that MSG may have a bi-phasic effect on appetite, with reduced satiation mediated by effects on palatability, but potential for enhanced post-ingestive satiety particularly in the context of protein ingestion.

  1. Organismal and spatial partitioning of energy and macronutrient transformations within a hypersaline mat

    Energy Technology Data Exchange (ETDEWEB)

    Mobberley, Jennifer M.; Lindemann, Stephen R.; Bernstein, Hans C.; Moran, James J.; Renslow, Ryan S.; Babauta, Jerome; Hu, Dehong; Beyenal, Haluk; Nelson, William C.

    2017-03-21

    Phototrophic mat communities are model ecosystems for studying energy cycling and elemental transformations because complete biogeochemical cycles occur over millimeter-to-centimeter scales. Characterization of energy and nutrient capture within hypersaline phototrophic mats has focused on specific processes and organisms, however little is known about community-wide distribution of and linkages between these processes. To investigate energy and macronutrient capture and flow through a structured community, the spatial and organismal distribution of metabolic functions within a compact hypersaline mat community from Hot Lake have been broadly elucidated through species-resolved metagenomics and geochemical, microbial diversity, and metabolic gradient measurements. Draft reconstructed genomes of abundant organisms revealed three dominant cyanobacterial populations differentially distributed across the top layers of the mat suggesting niche separation along light and oxygen gradients. Many organisms contained diverse functional profiles, allowing for metabolic response to changing conditions within the mat. Organisms with partial nitrogen and sulfur metabolisms were widespread indicating dependence upon metabolite exchange. In addition, changes in community spatial structure were observed over the diel. These results indicate that organisms within the mat community have adapted to the temporally dynamic environmental gradients in this hypersaline mat through metabolic flexibility and fluid syntrophic interactions, including shifts in spatial arrangements.

  2. Annual and Monthly Variations in Litter Macronutrients of Three Subalpine Forests in Western China

    Institute of Scientific and Technical Information of China (English)

    YANG Wan-Qin; WANG Kai-Yun; S.KELLOM(A)KI; ZHANG Jian

    2006-01-01

    Macronutrients (N, P, K, Ca, Mg, and S) in litter of three primarily spruce (Picea purpurea Masters) (SF), fir (Abies faxoniana Rehder & E. H. Wilson) (FF), and birch (Betula platyphylla Sukaczev) (BF) subalpine forests in western China were measured to understand the monthly variations in litter nutrient concentrations and annual and monthly nutrient returns via litterfall. Nutrient concentration in litter showed the rank order of Ca > N > Mg > K > S > P. Monthly variations in nutrient concentrations were greater in leaf litter (LL) than other litter components. The highest and lowest concentrations of N, P, K, and S in LL were found in the growing season and the nongrowing season, respectively, but Ca and Mg were the opposite. Nutrient returns via litterfall showed a marked monthly pattern with a major peak in October and one or two small peaks in February and/or May, varying with the element and stand type, but no marked monthly variations in nutrient returns via woody litter, reproductive litter, except in May for the BF, and moss litter. Not only litter production but also nutrient concentration controlled the annual nutrient return and the monthly nutrient return pattern. The monthly patterns of the nutrient concentration and return were of ecological importance for nutrient cycling and plant growth in the subalpine forest ecosystems.

  3. Macronutrient and sodium content in maize plants under cassava wastewater fertilization

    Directory of Open Access Journals (Sweden)

    Adriana G. Magalhães

    2016-03-01

    Full Text Available ABSTRACT This study aimed to evaluate the content of macronutrients and sodium in corn ( Zea mays plants as a function of different doses of cassava wastewater and ages of the plants after emergence. The experiment was conducted in a greenhouse in pots with capacity for 25 dm3 of soil, using a 5 × 3 factorial design with four replicates. The studied factors were doses of cassava wastewater: 0; 12.6; 25.2; 50.4; 75.6 m3 ha-1, and plant age: 20, 40 and 52 days after emergence (DAE. Potassium, calcium, magnesium, nitrogen, phosphorus, sodium and sulfur contents were evaluated in leaves and stalks. Nutritional deficiency of calcium was visible at 20 DAE. The increment in cassava wastewater doses increased N, P and K contents in plant shoots, but decreased Ca and Mg absorption. The contents of N, P and K in the leaves and N in stalks at 20 DAE were higher than at 40 and 52 DAE. The highest contents of P and K in the stalks occurred at 40 DAE.

  4. Dissolution kinetics of macronutrient fertilizers coated with manufactured zinc oxide nanoparticles.

    Science.gov (United States)

    Milani, Narges; McLaughlin, Mike J; Stacey, Samuel P; Kirby, Jason K; Hettiarachchi, Ganga M; Beak, Douglas G; Cornelis, Geert

    2012-04-25

    The solubility of Zn in Zn fertilizers plays an important role in the agronomic effectiveness of the fertilizer. On the basis of thermodynamics, zinc oxide (ZnO) nanoparticles (NPs) should dissolve faster and to a greater extent than bulk ZnO particles (equivalent spherical diameter >100 nm). These novel solubility features of ZnO NPs might be exploited to improve the efficiency of Zn fertilizers. In this study, we compared the Zn solubility and dissolution kinetics of ZnO nanoparticles and bulk ZnO particles coated onto two selected granular macronutrient fertilizers, urea and monoammonium phosphate (MAP). The main Zn species on coated MAP and urea granules were zinc ammonium phosphate and ZnO, respectively. Coated MAP granules showed greater Zn solubility and faster dissolution rates in sand columns compared to coated urea granules, which may be related to pH differences in the solution surrounding the fertilizer granules. The kinetics of Zn dissolution was not affected by the size of the ZnO particles applied for coating of either fertilizer type, possibly because solubility was controlled by formation of the same compounds irrespective of the size of the original ZnO particles used for coating.

  5. Associations between Maternal Body Composition and Appetite Hormones and Macronutrients in Human Milk

    Directory of Open Access Journals (Sweden)

    Sambavi Kugananthan

    2017-03-01

    Full Text Available Human milk (HM appetite hormones and macronutrients may mediate satiety in breastfed infants. This study investigated associations between maternal adiposity and concentrations of HM leptin, adiponectin, protein and lactose, and whether these concentrations and the relationship between body mass index and percentage fat mass (%FM in a breastfeeding population change over the first year of lactation. Lactating women (n = 59 provided milk samples (n = 283 at the 2nd, 5th, 9th and/or 12th month of lactation. Concentrations of leptin, adiponectin, total protein and lactose were measured. Maternal %FM was measured using bioimpedance spectroscopy. Higher maternal %FM was associated with higher leptin concentrations in both whole (0.006 ± 0.002 ng/mL, p = 0.008 and skim HM (0.005 ± 0.002 ng/mL, p = 0.007, and protein (0.16 ± 0.07 g/L, p = 0.028 concentrations. Adiponectin and lactose concentrations were not associated with %FM (0.01 ± 0.06 ng/mL, p = 0.81; 0.08 ± 0.11 g/L, p = 0.48, respectively. Whole milk concentrations of adiponectin and leptin did not differ significantly over the first year of lactation. These findings suggest that the level of maternal adiposity during lactation may influence the early appetite programming of breastfed infants by modulating concentrations of HM components.

  6. Associations between Maternal Body Composition and Appetite Hormones and Macronutrients in Human Milk

    Science.gov (United States)

    Kugananthan, Sambavi; Gridneva, Zoya; Lai, Ching T.; Hepworth, Anna R.; Mark, Peter J.; Kakulas, Foteini; Geddes, Donna T.

    2017-01-01

    Human milk (HM) appetite hormones and macronutrients may mediate satiety in breastfed infants. This study investigated associations between maternal adiposity and concentrations of HM leptin, adiponectin, protein and lactose, and whether these concentrations and the relationship between body mass index and percentage fat mass (%FM) in a breastfeeding population change over the first year of lactation. Lactating women (n = 59) provided milk samples (n = 283) at the 2nd, 5th, 9th and/or 12th month of lactation. Concentrations of leptin, adiponectin, total protein and lactose were measured. Maternal %FM was measured using bioimpedance spectroscopy. Higher maternal %FM was associated with higher leptin concentrations in both whole (0.006 ± 0.002 ng/mL, p = 0.008) and skim HM (0.005 ± 0.002 ng/mL, p = 0.007), and protein (0.16 ± 0.07 g/L, p = 0.028) concentrations. Adiponectin and lactose concentrations were not associated with %FM (0.01 ± 0.06 ng/mL, p = 0.81; 0.08 ± 0.11 g/L, p = 0.48, respectively). Whole milk concentrations of adiponectin and leptin did not differ significantly over the first year of lactation. These findings suggest that the level of maternal adiposity during lactation may influence the early appetite programming of breastfed infants by modulating concentrations of HM components. PMID:28282925

  7. Assessment of macronutrients and heavy metals in Fagonia cretica Linn of Pakistan by atomic spectroscopy

    Directory of Open Access Journals (Sweden)

    K. Naeem

    2014-05-01

    Full Text Available The macronutrients and heavy metals content of different parts of a locally found herb named Fagonia cretica, an important medicinal herb, were investigated. Al, Ca, Co, Cr, Cu, Fe, K, Mg, Mn, Na, Sr and Zn were measured in roots, shoots, leaves, spines and flowers/fruits of the plant. The analysis was carried out by inductively coupled plasma optical emission spectrometry (ICP-OES and atomic absorption spectrophotometry (AAS. The results revealed that the Fagonia cretica accumulate the elemental contents at different parts. The accuracy of the method was checked by analysing a certified reference material and the results were in agreement with the enumerate value. The presence of a certain set of elements at percentage level like Ca, K and Mg is useful for strengthening of bones and body. Other elements important from health perspective including Al, Co, Cr, Cu, Fe, Mn, Na, Sr and Zn are found at ppm levels in all parts of the plant. DOI: http://dx.doi.org/10.4314/bcse.v28i2.2

  8. Mood and the macro-nutrient composition of breakfast and the mid-day meal.

    Science.gov (United States)

    Benton, David; Brock, Helen

    2010-12-01

    Six hundred and eighty-six individuals were approached at mid-day after they had chosen a meal in a cafeteria. They were asked to rate their mood during the morning and list what they had eaten that morning. Both males and females who had eaten breakfast rather than fasting reported that they had been happier and more relaxed during the morning. The macro-nutrient compositions of breakfast and lunch were calculated and related to mood during the morning. In males, but not females, the consumption of more carbohydrate in the morning was associated with feeling happy rather than sad and relaxed rather than stressed. Further examination demonstrated that in males the amount of fat, protein and total energy consumed was not associated with mood; that is there was a selective relationship between carbohydrate intake and mood. It was not possible to establish whether the nature of breakfast influenced mood or the pre-existing mood influenced the choice of breakfast although both explanations are plausible. In females, however, there was no relationship between carbohydrate intake and mood, possibly a reflection of the smaller amounts consumed. The suggestion that mood during the morning might influence food choice at mid-day was considered but no association was found.

  9. Maize dry matter production and macronutrient extraction model as a new approach for fertilizer rate estimation

    Directory of Open Access Journals (Sweden)

    KARLA V. MARTINS

    Full Text Available ABSTRACT Decision support for nutrient application remains an enigma if based on soil nutrient analysis. If the crop could be used as an auxiliary indicator, the plant nutrient status during different growth stages could complement the soil test, improving the fertilizer recommendation. Nutrient absorption and partitioning in the plant are here studied and described with mathematical models. The objective of this study considers the temporal variation of the nutrient uptake rate, which should define crop needs as compared to the critical content in soil solution. A uniform maize crop was grown to observe dry matter accumulation and nutrient content in the plant. The dry matter accumulation followed a sigmoidal model and the macronutrient content a power model. The maximum nutrient absorption occurred at the R4 growth stage, for which the sap concentration was successfully calculated. It is hoped that this new approach of evaluating nutrient sap concentration will help to develop more rational ways to estimate crop fertilizer needs. This new approach has great potential for on-the-go crop sensor-based nutrient application methods and its sensitivity to soil tillage and management systems need to be examined in following studies. If mathematical model reflects management impact adequately, resources for experiments can be saved.

  10. SOIL EXCHANGEABLE ALUMINUM INFLUENCING THE GROWTH AND LEAF TISSUE MACRONUTRIENTS CONTENT OF CASTOR PLANTS

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    ROSIANE DE LOURDES SILVA DE LIMA

    2014-01-01

    Full Text Available Three castor ( Ricinus communis genotypes were studied regarding tolerance to high exchange factorial distribution of five doses of exchangeable aluminum added to the soil (0, 0.15, 0.30, 0.60, and 1.20 cmol c dm - 3 and three castor genotypes (BRS Nordestina, BRS Paraguaçu, and Lyra. The plants were raised in pots in a greenhouse. At 53 days after emergence, data were taken on plant height, leaf area, dry mass of shoot and root, and leaf tissue content of macronutrients. The most sensitive genotype was the cv. BRS Nordestina, in which the shoot and root dry weight in the highest aluminum content were reduced to 12.9% and 16.2% of the control treatment, respectively. The most tolerant genotype was the hybrid Lyra, in which the shoot and root dry weight in the maximum content of aluminum were reduced to 43.5% and 42.7% of the control treatment, respectively.The increased exchangeable aluminum affected the leaf nutrient content, and the intensity of the response was different among cultivars. The aluminum toxicity increased N, Ca, and Mg contents and reduced on P, K, and S contents. The cv. BRS Nordestina had a drastic shoot dry weight reduction associated with an intense increment in the N leaf content. Thus, the N increment was caused by a concentration effect caused by the limited growth.

  11. Variation in macronutrients in human bank milk: influencing factors and implications for human milk banking

    DEFF Research Database (Denmark)

    Michaelsen, K F; Skafte, L; Badsberg, J H;

    1990-01-01

    Protein (P), fat (F), and carbohydrate (C) concentration in expressed human bank milk was determined by infrared analysis of 2,554 samples from 224 mothers. The mean contents of P, F, C, and energy (E, calculated from P, F, and C) were 9.0 g/L, 39.0 g/L, 71.9 g/L, and 696 kcal/L, respectively...... with a high P content, we have developed a "high-protein" milk with a P content of about 12 g/L (true protein) and an E content of about 725 kcal/L. Thus, by continuous monitoring of macronutrient content in human bank milk it is possible to develop a "high-protein" milk with sufficient P and E content....... The main results were as follows: the P and F contents increased slightly with increasing body mass index of the mother, the P content decreased with increasing amounts of milk delivered to the milk bank, and the F content was higher in mothers delivering large amounts of milk. By selecting incoming milk...

  12. Dry matter and macronutrient accumulation in fruits of Conilon coffee with different ripening cycles

    Directory of Open Access Journals (Sweden)

    Fábio Luiz Partelli

    2014-02-01

    Full Text Available The period between anthesis and fruit ripening varies according to the Conilon coffee (Coffea canephora genotype. Therefore, the time of the nutritional requirements for fruit formation may differ, depending on the formation phase and the genotype, and may directly affect split application of fertilizer. The aim of this study was to quantify the accumulation of dry matter and N, P, K, Ca, Mg and S at several stages in the fruit of the Conilon coffee genotype with different ripening cycles, which may suggest the need for split application of fertilizer in coffee. The experiment was carried out in the municipality of Nova Venecia, Espírito Santo, Brazil, throughout the reproductive cycle. The treatments were composed of four coffee genotypes with different ripening cycles. A completely randomised experimental design was used. with five replicates. Plagiotropic branches were harvested from flowering to fruit ripening at 28-day intervals to determine the dry matter of the fruits and the concentration and accumulation of the nutrients they contained. The behavior of dry matter and macronutrient accumulation during the study period was similar and increasing, but it differed among genotypes sampled in the same season. Early genotypes exhibited a higher speed of dry matter and nutrient accumulation. Split application of fertilizer should differ among coffee genotypes with different ripening cycles (early, intermediate, late and very late.

  13. Macronutrient accumulation and partioning in fertigated sweet pepper plants Acúmulo e participação de macronutrientes em plantas de pimentão fertirrigadas

    Directory of Open Access Journals (Sweden)

    Francisco Fernando Noronha Marcussi

    2004-02-01

    Full Text Available Information on nutrient demand during each growth stage is essential for efficient application of nutrients. A pot experiment was carried out with a Typic Hapludox under greenhouse conditions in Botucatu, SP, Brazil, aiming was to determine nutrient uptake and partition of sweet pepper plants, cultivar Elisa in randomized block design with four replications. The fertigation was simulated through 2-L PET bottles (neck down with a tube and a flow regulator at the end, simulating a drip irrigation system. Four plants per replication were collected at eight growth stages (0, 20, 40, 60, 80, 100, 120 and 140 days after the seedling transplant - DAT. The period of largest extraction of nutrients for the plant occurred from 120 to 140 DAT, which coincides with the highest accumulation of dry phytomass. The highest Mg and Ca accumulation occurred in the leaves, while N, K, S and P were mostly accumulated in the fruits. Only 8 to 13% of the total amount of the accumulated macronutrientes at 140 DAT were absorbed up to the 60th DAT. Between the 61st and 100th DAT, K was the most absorbed macronutrient (60% of the macronutrients accumulated during the whole cycle. P, Ca and S were the most absorbed nutrients at the end of the cycle. Considering rates (g per plant, the most absorbed macronutrients were: N (6.6 > K (6.4 > Ca (2.6 > Mg (1.3 > S (1.1 > P (0.7.A demanda de nutrientes em cada etapa do crescimento de uma planta é uma informação essencial para que se possa aplicar os nutrientes de forma mais eficiente. Com objetivo de determinar a marcha de absorção e a partição de macronutrientes em plantas de pimentão cultivar Elisa foi conduzido um experimento em vasos de 29 dm³ contendo um Latossolo Vermelho aluminoférrico sob condições de cultivo protegido em Botucatu, SP em delineamento experimental em blocos ao acaso com quatro repetições. A fertirrigação foi simulada utilizando garrafas (2 L com uma mangueira e um controlador de vazão na

  14. Effect of Human Milk Appetite Hormones, Macronutrients, and Infant Characteristics on Gastric Emptying and Breastfeeding Patterns of Term Fully Breastfed Infants.

    Science.gov (United States)

    Gridneva, Zoya; Kugananthan, Sambavi; Hepworth, Anna R; Tie, Wan J; Lai, Ching T; Ward, Leigh C; Hartmann, Peter E; Geddes, Donna T

    2016-12-28

    Human milk (HM) components influence infant feeding patterns and nutrient intake, yet it is unclear how they influence gastric emptying (GE), a key component of appetite regulation. This study analyzed GE of a single breastfeed, HM appetite hormones/macronutrients and demographics/anthropometrics/body composition of term fully breastfed infants (n = 41, 2 and/or 5 mo). Stomach volumes (SV) were calculated from pre-/post-feed ultrasound scans, then repeatedly until the next feed. Feed volume (FV) was measured by the test-weigh method. HM samples were analyzed for adiponectin, leptin, fat, lactose, total carbohydrate, lysozyme, and total/whey/casein protein. Linear regression/mixed effect models were used to determine associations between GE/feed variables and HM components/infant anthropometrics/adiposity. Higher FVs were associated with faster (-0.07 [-0.10, -0.03], p whey protein concentration was associated with higher post-feed SVs (4.99 [0.84, 9.13], p = 0.023). Longer GE time was associated with higher adiponectin concentration (2.29 [0.92, 3.66], p = 0.002) and dose (0.02 [0.01, 0.03], p = 0.005), and lower casein:whey ratio (-65.89 [-107.13, -2.66], p = 0.003). FV and HM composition influence GE and breastfeeding patterns in term breastfed infants.

  15. Macronutrients, Phytochemicals, and Antioxidant Activity of Soybean Sprout Germinated with or without Light Exposure.

    Science.gov (United States)

    Chen, Yeming; Chang, Sam K C

    2015-06-01

    This study examined the macronutrients, phytochemicals, and antioxidant activities of yellow soybean sprout (YSS) and green soybean sprout (GSS) with different germination days. YSS and GSS were obtained by sprouting soybean in darkness or with light exposure at 21 °C. Lipid, protein, carbohydrate, and ash contents were analyzed before and after soybean germination. Phytochemicals (total phenolic compounds, saponin, and isoflavone) were also determined. DPPH, ferric reducing antioxidant power (FRAP), and oxygen radical absorbance capacity (ORAC) were determined to examine the antioxidant activities of soybean sprout. Results showed YSS had a higher yield than GSS. Based on dry mass composition, 7-d germination of GSS decreased 14% protein, 37% lipid, 22% carbohydrate, and 16% ash, whereas 7-d germination of YSS decreased 6% protein and 47% lipid. Carbohydrate did not change and ash significantly increased for the 7-d germinated YSS. Lipid was greatly metabolized in germination, which explained why the protein relative percentage in dried soybean sprout was higher than that in the corresponding soybean. Total phenolic compounds and saponin (mg/g soybean sprout, dry basis) had the same accumulation trend in soybean sprout with the increases in germination days. Aglycone isoflavones (genistein, glycitein, and daidzein) and daidzin showed an increased trend, whereas malonylgenistin and malonylglycitin showed a decreased trend with germination days for both GSS and YSS. The change in other isoflavones did not show definite trends. GSS had 20% more antioxidant activities than YSS (7-d germinated soybean sprout). The increases in ORAC antioxidant activity suggest eating GSS may be more beneficial than GSS for promoting human health.

  16. Serum adiponectin concentration in relation to macronutrient and food intake in young Japanese women.

    Science.gov (United States)

    Murakami, Kentaro; Sasaki, Satoshi; Uenishi, Kazuhiro

    2013-01-01

    Little is known about the relation of modifiable dietary factors to circulating adiponectin concentrations, particularly in young adults and non-Western populations. The aim of this study was to determine the association between macronutrient and food intake and serum adiponectin concentration in a group of young Japanese women. This cross-sectional study included 1047 female Japanese dietetic students aged 18 to 22 y. Using a validated, self-administered, comprehensive diet history questionnaire, we assessed intake of nutrients (protein, total fat, saturated fatty acids, monounsaturated fatty acids, and polyunsaturated fatty acids, carbohydrates, and dietary fiber) and foods (rice, bread, noodles, potatoes, confectioneries, fats and oils, pulses, fish and shellfish, meats, eggs, dairy products, vegetables, fruits, coffee, green and oolong tea, black tea, and soft drinks) and glycemic index and load. Fasting blood samples were collected and serum adiponectin concentrations were measured. Adjustment was made for survey year, region, municipality level, current smoking, current alcohol drinking, physical activity, body mass index, energy intake, and intakes of other nutrients or foods. After adjustment for potential confounding factors, none of the nutrients examined was a significant determinant of serum adiponectin concentration. There was no association for glycemic index or load. Coffee was the only food significantly and independently associated with serum adiponectin concentration. Mean (SE) values of serum adiponectin concentration for each quartile of coffee intake were 12.4 (0.2), 12.4 (0.5), 12.5 (0.3), and 13.2 (0.3) μg/mL, respectively (P for trend = 0.04). In a group of young Japanese women, higher coffee intake was independently associated with higher serum adiponectin concentration. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. A genetic risk tool for obesity predisposition assessment and personalized nutrition implementation based on macronutrient intake.

    Science.gov (United States)

    Goni, Leticia; Cuervo, Marta; Milagro, Fermín I; Martínez, J Alfredo

    2015-01-01

    There is little evidence about genetic risk score (GRS)-diet interactions in order to provide personalized nutrition based on the genotype. The aim of the study was to assess the value of a GRS on obesity prediction and to further evaluate the interactions between the GRS and dietary intake on obesity. A total of 711 seekers of a Nutrigenetic Service were examined for anthropometric and body composition measurements and also for dietary habits and physical activity. Oral epithelial cells were collected for the identification of 16 SNPs (related with obesity or lipid metabolism) using DNA zip-coded beads. Genotypes were coded as 0, 1 or 2 according to the number of risk alleles, and the GRS was calculated by adding risk alleles with such a criterion. After being adjusted for gender, age, physical activity and energy intake, the GRS demonstrated that individuals carrying >7 risk alleles had in average 0.93 kg/m(2) of BMI, 1.69 % of body fat mass, 1.94 cm of waist circumference and 0.01 waist-to-height ratio more than the individuals with ≤7 risk alleles. Significant interactions for GRS and the consumption of energy, total protein, animal protein, vegetable protein, total fat, saturated fatty acids, polyunsaturated fatty acids, total carbohydrates, complex carbohydrates and fiber intake on adiposity traits were found after adjusted for confounders variables. The GRS confirmed that the high genetic risk group showed greater values of adiposity than the low risk group and demonstrated that macronutrient intake modifies the GRS association with adiposity traits.

  18. Relationship between Milk Microbiota, Bacterial Load, Macronutrients, and Human Cells during Lactation.

    Science.gov (United States)

    Boix-Amorós, Alba; Collado, Maria C; Mira, Alex

    2016-01-01

    Human breast milk is considered the optimal nutrition for infants, providing essential nutrients and a broad range of bioactive compounds, as well as its own microbiota. However, the interaction among those components and the biological role of milk microorganisms is still uncovered. Thus, our aim was to identify the relationships between milk microbiota composition, bacterial load, macronutrients, and human cells during lactation. Bacterial load was estimated in milk samples from a total of 21 healthy mothers through lactation time by bacteria-specific qPCR targeted to the single-copy gene fusA. Milk microbiome composition and diversity was estimated by 16S-pyrosequencing and the structure of these bacteria in the fluid was studied by flow cytometry, qPCR, and microscopy. Fat, protein, lactose, and dry extract of milk as well as the number of somatic cells were also analyzed. We observed that milk bacterial communities were generally complex, and showed individual-specific profiles. Milk microbiota was dominated by Staphylococcus, Pseudomonas, Streptococcus, and Acinetobacter. Staphylococcus aureus was not detected in any of these samples from healthy mothers. There was high variability in composition and number of bacteria per milliliter among mothers and in some cases even within mothers at different time points. The median bacterial load was 10(6) bacterial cells/ml through time, higher than those numbers reported by 16S gene PCR and culture methods. Furthermore, milk bacteria were present in a free-living, "planktonic" state, but also in equal proportion associated to human immune cells. There was no correlation between bacterial load and the amount of immune cells in milk, strengthening the idea that milk bacteria are not sensed as an infection by the immune system.

  19. Energy and macronutrient intake in adolescent sprint athletes: a follow-up study.

    Science.gov (United States)

    Aerenhouts, Dirk; Deriemaeker, Peter; Hebbelinck, Marcel; Clarys, Peter

    2011-01-01

    Macronutrient intake, height, weight, and body composition of 60 adolescent sprint athletes were estimated every 6 months over 3 years. Seven-day food records were analysed based on the Belgian and Dutch food databanks. The age of participants at the start of the 3-year study was 14.8 ± 1.6 years for female athletes and 14.7 ± 1.9 years for male athletes. Girls and boys gained height (3.4 ± 4.6 cm and 5.9 ± 6.6 cm respectively) and weight (5.6 ± 3.5 kg and 8.7 ± 5.5 kg respectively), whereas percent body fat remained unchanged in both girls and boys (around 17.0% and 8.5% respectively). Mean protein intake of around 1.5 g · kg⁻¹ body weight was within recommendations on each occasion for both sexes. Carbohydrate intakes between 5 and 7 g · kg⁻¹ body weight support a training programme of moderate intensity. Total and saturated fat intakes were high at the start of the study (girls: 31.8 ± 3.5% and 12.2 ± 2.0% of energy intake; boys: 30.3 ± 4.6% and 12.0 ± 1.9% of energy intake) and it appeared to be difficult to achieve and maintain lower intakes. Consistent low fluid intakes around 40 ml · kg⁻¹ body weight were observed. General non-stringent advice for improvement of the diet resulted in significant favourable changes only for the consumption of wholegrain bread, vegetables, and soft drinks. Dietary habits of adolescent sprint athletes are not always according to guidelines and are relatively stable but repeated advice can induce moderate improvements.

  20. Vertical stratification of the nutritional value of fruit: macronutrients and condensed tannins.

    Science.gov (United States)

    Houle, Alain; Conklin-Brittain, Nancy L; Wrangham, Richard W

    2014-12-01

    Competing successfully for the best feeding sites is an important behavioral strategy but little is known about how feeding sites vary nutritionally within a fruit tree. To answer this question we tested how the nutritional value of a fruit is influenced by its ripeness and its height within the tree crown. A complementary objective was to assess the nutritional value of the midripe fruit, a food item rarely mentioned in the literature despite being exploited on a daily basis by many frugivores. We measured how the dry weight of pulp, water content, and concentration of macronutrients and condensed tannins varied within the tree crowns of 15 fruit species. Collections occurred early in the fruiting cycle, so as to assess the amount of food in the tree before its exploitation by primates. We found that (1) the upper crown produced fruit densities 4.2 times higher, and a fruit crop 4.8 times larger, than the lower crown of the same tree; (2) considering only midripe and ripe stages, upper-crown fruits contained 28.6% more dry pulp, 21.1% more water, and 13.5% more sugars per dry matter than lower-crown fruits of the same tree; (3) midripe fruits contained 80% of the concentrations of sugars of ripe fruits, making them a sweeter food item than one would expect from the intermediate color of their epidermis; (4) cellulose, hemicellulose, proteins, and ash proportionally decreased in concentration while dry pulp and sugars increased during ripening; and (5) ripe fruits were usually rare in the tree (nutritional explanation for why tree-feeding frugivores compete for the highest feeding sites.

  1. Relationship between milk microbiota, bacterial load, macronutrients and human cells during lactation

    Directory of Open Access Journals (Sweden)

    Alba eBOIX-AMORÓS

    2016-04-01

    Full Text Available Human breast milk is considered the optimal nutrition for infants, providing essential nutrients and a broad range of bioactive compounds, as well as its own microbiota. However, the interaction among those components and the biological role of milk microorganisms is still uncovered. Thus, our aim was to identify the relationships between milk microbiota composition, bacterial load, macronutrients and human cells during lactation. Bacterial load was estimated in milk samples from a total of 21 healthy mothers through lactation time by bacteria-specific qPCR targeted to the single-copy gene fusA . Milk microbiome composition and diversity was estimated by 16S-pyrosequencing and the structure of these bacteria in the fluid was studied by flow cytometry, qPCR and microscopy. Fat, protein, lactose and dry extract of milk as well as the number of somatic cells were also analyzed. We observed that milk bacterial communities were generally complex, and showed individual-specific profiles. Milk microbiota was dominated by Staphylococcus, Pseudomonas, Streptococcus and Acinetobacter. Staphylococcus aureus was not detected in any of these samples from healthy mothers. There was high variability in composition and number of bacteria per milliliter among mothers and in some cases even within mothers at different time points. The median bacterial load was 106 bacterial cells/ml through time, higher than those numbers reported by 16S gene PCR and culture methods.. Furthermore, milk bacteria were present in a free-living, planktonic state, but also in equal proportion associated to human immune cells. There was no correlation between bacterial load and the amount of immune cells in milk, strengthening the idea that milk bacteria are not sensed as an infection by the immune system.

  2. Macronutrient uptake, accumulation and export by the irrigated 'vitória' pineapple plant

    Directory of Open Access Journals (Sweden)

    Rodinei Facco Pegoraro

    2014-06-01

    Full Text Available The nutritional state of the pineapple plant has a large effect on plant growth, on fruit production, and fruit quality. The aim of this study was to assess the uptake, accumulation, and export of nutrients by the irrigated 'Vitória' pineapple plant during and at the end of its development. A randomized block statistical design with four replications was used. The treatments were defined by different times of plant collection: at 270, 330, 390, 450, 510, 570, 690, 750, and 810 days after planting (DAP. The collected plants were separated into the following components: leaves, stem, roots, fruit, and slips for determination of fresh and dry matter weight at 65 ºC. After drying, the plant components were ground for characterization of the composition and content of nutrients taken up and exported by the pineapple plant. The results were subjected to analysis of variance, and non-linear regression models were fitted for the significant differences identified by the F test (p N > S > Ca > Mg > P, which corresponded to 898, 452, 134, 129, 126, and 107 kg ha-1, respectively, of total accumulation. The export of macronutrients by the pineapple fruit was in the following decreasing order: K > N > S > Ca > P > Mg, which was equivalent to 18, 17, 11, 8, 8, and 5 %, respectively, of the total accumulated by the pineapple. The 'Vitória' pineapple plant exported 78 kg ha-1 of N, 8 kg ha-1 of P, 164 kg ha-1 of K, 14 kg ha-1 of S, 10 kg ha-1 of Ca, and 6 kg ha-1 of Mg by the fruit. The nutrient content exported by the fruits represent important components of nutrient extraction from the soil, which need to be restored, while the nutrients contained in the leaves, stems and roots can be incorporated in the soil within a program of recycling of crop residues.

  3. Macronutrients, aluminium from drinking water and foods, and other metals in cognitive decline and dementia.

    Science.gov (United States)

    Solfrizzi, Vincenzo; Colacicco, Anna Maria; D'Introno, Alessia; Capurso, Cristiano; Parigi, Angelo Del; Capurso, Sabrina A; Torres, Francesco; Capurso, Antonio; Panza, Francesco

    2006-11-01

    A possible role of the macronutrients and the basic elements of carbohydrates (glucose administration or depletion), proteins (amino acids such as tryptophan and tyrosine), and fat (unsaturated fatty acids) was recently proposed for age-related changes of cognitive function, and the cognitive decline of degenerative (AD) or vascular origin. The availability and utilization of glucose has been implicated in cognitive function not only as a result of nutritional and systemic metabolic conditions, but also, although speculatively, as a crucial phase of the mechanism of action of molecules used as cognitive-enhancers. Furthermore, many lines of evidence have focused on the importance of oxidative stress mechanisms and free radical damage in AD pathogenesis. In addition, epidemiological studies have recently reported an association between alcohol and the incidence of AD and predementia syndromes. Foods with large amounts of aluminium-containing additives or aluminium from drinking water may affect the risk of developing AD, aluminium more likely acting as a cofactor somewhere in the cascade of events leading to the demented brain. A role for other metals in dementia have been speculated, given the encouraging results reported from studies on peripheral zinc concentrations, zinc supplementation, serum copper, either bound with ceruloplasmin or not, and iron metabolism in AD. Nonetheless, more data are needed to support a possible role of these metals in dementing diseases. Healthy diets, antioxidant supplements, and the prevention of nutritional deficiencies or exposure to foods and water with high content of metals could be considered the first line of defence against the development and progression of cognitive decline.

  4. Effect of dietary macronutrients on postprandial incretin hormone release and satiety in obese and normal-weight women.

    Science.gov (United States)

    Wikarek, Tomasz; Chudek, Jerzy; Owczarek, Aleksander; Olszanecka-Glinianowicz, Magdalena

    2014-01-28

    The aim of the present study was to assess the effect of dietary macronutrients on postprandial incretin responses and satiety and hunger sensation in obese and normal-weight women. A total of eleven obese and nine normal-weight women were recruited for the assessment of plasma concentrations of glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP) and insulin and the sensation of satiety and hunger using a visual analogue scale before and during a 6 h period after administration of three different macronutrient test meals. The AUCtotal GLP-1 and AUCtotal GIP values were decreased in obese women after the consumption of a fatty meal and all the test meals, respectively. However, the AUCtotal insulin value after a carbohydrate meal was greater in the obese group. The AUCtotal satiety value was decreased only after the intake of the protein meal in obese women when compared with normal-weight women. After the consumption of the fatty meal, a significant positive correlation between maximum satiety sensation and the AUCtotal GLP-1 value in the obese group and that between minimum hunger sensation and the AUCtotal GLP-1 value in the normal-weight group were observed. In conclusion, the findings of the present study suggest that: (1) satiety sensation after consumption of carbohydrate and protein meals in the obese group is related to the postprandial insulin response, while after consumption of a fatty meal, it is related to the postprandial GLP-1 release; (2) the postprandial GIP response does not influence the sensation of satiety and hunger; (3) the reduced GLP-1 release after the intake of a fatty meal in obese individuals may explain impaired satiety sensation; (4) the impaired postprandial GIP response is not related to the consumption of macronutrients and may be the early indicator of incretin axis dysfunction in obese women.

  5. Dietary macronutrients and food consumption as determinants of long-term weight change in adult populations: a systematic literature review

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    Mikael Fogelholm

    2012-08-01

    Full Text Available This systematic literature review examined the role of dietary macronutrient composition, food consumption and dietary patterns in predicting weight or waist circumference (WC change, with and without prior weight reduction. The literature search covered year 2000 and onwards. Prospective cohort studies, case–control studies and interventions were included. The studies had adult (18–70 y, mostly Caucasian participants. Out of a total of 1,517 abstracts, 119 full papers were identified as potentially relevant. After a careful scrutiny, 50 papers were quality graded as A (highest, B or C. Forty-three papers with grading A or B were included in evidence grading, which was done separately for all exposure-outcome combinations. The grade of evidence was classified as convincing, probable, suggestive or no conclusion. We found probable evidence for high intake of dietary fibre and nuts predicting less weight gain, and for high intake of meat in predicting more weight gain. Suggestive evidence was found for a protective role against increasing weight from whole grains, cereal fibre, high-fat dairy products and high scores in an index describing a prudent dietary pattern. Likewise, there was suggestive evidence for both fibre and fruit intake in protection against larger increases in WC. Also suggestive evidence was found for high intake of refined grains, and sweets and desserts in predicting more weight gain, and for refined (white bread and high energy density in predicting larger increases in WC. The results suggested that the proportion of macronutrients in the diet was not important in predicting changes in weight or WC. In contrast, plenty of fibre-rich foods and dairy products, and less refined grains, meat and sugar-rich foods and drinks were associated with less weight gain in prospective cohort studies. The results on the role of dietary macronutrient composition in prevention of weight regain (after prior weight loss were inconclusive.

  6. Macronutrient composition of the diet and prospective weight change in participants of the EPIC-PANACEA study.

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    Anne-Claire Vergnaud

    Full Text Available BACKGROUND: The effect of the macronutrient composition of the usual diet on long term weight maintenance remains controversial. METHODS: 373,803 subjects aged 25-70 years were recruited in 10 European countries (1992-2000 in the PANACEA project of the EPIC cohort. Diet was assessed at baseline using country-specific validated questionnaires and weight and height were measured at baseline and self-reported at follow-up in most centers. The association between weight change after 5 years of follow-up and the iso-energetic replacement of 5% of energy from one macronutrient by 5% of energy from another macronutrient was assessed using multivariate linear mixed-models. The risk of becoming overweight or obese after 5 years was investigated using multivariate Poisson regressions stratified according to initial Body Mass Index. RESULTS: A higher proportion of energy from fat at the expense of carbohydrates was not significantly associated with weight change after 5 years. However, a higher proportion of energy from protein at the expense of fat was positively associated with weight gain. A higher proportion of energy from protein at the expense of carbohydrates was also positively associated with weight gain, especially when carbohydrates were rich in fibre. The association between percentage of energy from protein and weight change was slightly stronger in overweight participants, former smokers, participants ≥60 years old, participants underreporting their energy intake and participants with a prudent dietary pattern. Compared to diets with no more than 14% of energy from protein, diets with more than 22% of energy from protein were associated with a 23-24% higher risk of becoming overweight or obese in normal weight and overweight subjects at baseline. CONCLUSION: Our results show that participants consuming an amount of protein above the protein intake recommended by the American Diabetes Association may experience a higher risk of becoming

  7. Diet-induced obesity in ad libitum-fed mice: food texture overrides the effect of macronutrient composition.

    Science.gov (United States)

    Desmarchelier, Charles; Ludwig, Tobias; Scheundel, Ronny; Rink, Nadine; Bader, Bernhard L; Klingenspor, Martin; Daniel, Hannelore

    2013-04-28

    Diet-induced obesity in mice can be achieved through the use of diets with different macronutrient compositions and textures. We aimed at determining the contribution of macronutrient composition to obesity development and associated pathophysiological changes in mice. C57BL/6N mice were offered a control, a high-fat or a Western-style diet, either as pellet (H for hard) or with identical composition in powder form (S for soft), resulting in C-S, C-H, HF-H, HF-S, W-H and W-S groups, respectively. Body fat distribution, expression levels of selected target genes in adipose tissues, clinical chemistry and hormone concentration in the blood, as well as liver TAG content were measured. The most striking finding was that all mice fed the different powder diets developed obesity with similar weight gain, whereas among the mice fed the pellet diets, only those given the HF and W diets became obese. This allowed us to separate diet-specific effects from obesity-mediated effects. Irrespective of the food texture, the W diet induced a more severe hepatosteatosis and higher activities of serum transaminases compared with the two other diets. Adipose tissue gene expression analysis revealed that leptin and adiponectin levels were not affected by the dietary composition per se, whereas uncoupling protein 1 and 11β-hydroxysteroid dehydrogenase type 1 levels were decreased by both dietary composition and changes in body weight. In conclusion, diets differing in macronutrient composition elicit specific pathophysiological changes, independently of changes in body weight. A diet high in both fat and sugars seems to be more deleterious for the liver than a HF diet.

  8. Energy and macronutrient intake over the course of the day of German adults: A DEDIPAC-study.

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    Wittig, Friederike; Hummel, Eva; Wenzler, Germaine; Heuer, Thorsten

    2017-07-01

    The aim of the study was to analyze the energy and macronutrient intake over the course of the day of selected population groups in Germany defined by sex, age, BMI, SES, and diet quality. The study was based on food consumption data from the German National Nutrition Survey II (2005-2007) assessed by two 4-day dietary weighing records of 662 women and men aged between 18 and 80 years. Energy and macronutrient intake were calculated using the German Nutrient Database 3.02 and summarized for the periods 'morning', 'midday', 'afternoon', 'evening', and 'night'. Generalized estimating equation models were used to examine differences in energy and macronutrient intake. For women and men, a three-main-meal pattern ('morning', 'midday', and 'evening') was observed, indicated as peaks in energy intake at 08:00 to 09:00, 13:00 and 19:00 o'clock. The distributions of carbohydrate, protein, and fat intake mirror the distribution of energy intake over the course of the day. The highest energy intake was found in the 'evening' period, especially in young adults, overweight persons, persons with a high SES, and men with a low diet quality. Women of the oldest age group showed a similar energy intake across the three-main-meals in contrast to young adults, who had lower peaks in the 'morning' and 'midday' periods as well as a shift to later meal times. Young adults seem to have a higher variability in energy intake and a less distinct meal pattern, while seniors have a more structured day. Because a high energy intake in the 'evening' period is associated with negative health-related factors, the distribution of energy intake should be considered by recommendations for a healthy nutritional behavior. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  9. Effects of macronutrient composition and cyclooxygenase-inhibition on diet-induced obesity, low grade inflammation and glucose homeostasis

    DEFF Research Database (Denmark)

    Fjære, Even

    - or protein based background, and supplemented with either corn- or fish oil. These experiments were conducted to determine whether macronutrient composition and type of dietary fat can modulate diet-induced obesity, and associated metabolic consequences. The use of non-steroidal anti-inflammatory drugs...... is escalating, and in view of the increased consumption of obesogenic diets with high levels of dietary carbohydrates and fat, the metabolic consequences of cyclooxygenase-inhibition warrants investigation. Results: High fat/high sucrose diets increased obesity development and expression of macrophage...

  10. Effects of dietary macronutrient composition on exogenous neuropeptide Y's stimulation of food intake in chicks.

    Science.gov (United States)

    Nelson, Laura A; Gilbert, Elizabeth R; Cline, Mark A

    2015-03-30

    In mammalian models it is well documented that the potent orexigenic factor, neuropeptide Y (NPY) causes preferential intake of high carbohydrate and fat diets; however, information on this is limited in non-mammalian species. The purpose of this study was to determine the influence of dietary macronutrient composition on NPY's orexigenic effect in chicks. Three isocaloric diets were formulated: high carbohydrate, fat and protein. In Experiment 1, chicks were fed the three diets and received intracerebroventricular injections of 0.2 or 2.0nmol NPY. Chicks that consumed the high carbohydrate and protein diets had a non-dose dependent similar magnitude of increased food intake after NPY injection, but those on the high fat diet had a dose dependent food intake increase. In Experiment 2, when chicks were given free access to all three diets, injection of 0.2nmol NPY caused preferential increase in intake of only the high protein diet whereas 2.0nmol NPY caused preferential increases in of both high carbohydrate and protein diets. Neither dose affected high fat diet intake. In Experiment 3, chicks were raised on one of the three diets and then switched to the others. When chicks were raised on the high fat and protein diets and then switched to the other diets, stimulation of food intake occurred for the same duration, 180min. However, when chicks were raised on the high carbohydrate and then switched to high fat, NPY injection caused a sustaining increase in cumulative food intake that lasted the entire observation period. These results suggest that NPY has selective effects on consumption of carbohydrate, fat and protein in chicks, and that diet in turn affects the NPY-mediated response in food intake, with a high fat diet enhancing NPY sensitivity that is associated with a greater magnitude and duration of feeding response. In turn, NPY caused preferential protein and carbohydrate intake instead of fat intake (in this order of preference), when chicks had the

  11. Fate of Zinc Oxide Nanoparticles Coated onto Macronutrient Fertilizers in an Alkaline Calcareous Soil.

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    Narges Milani

    Full Text Available Zinc oxide (ZnO nanoparticles may provide a more soluble and plant available source of Zn in Zn fertilizers due to their greater reactivity compared to equivalent micron- or millimetre-sized (bulk particles. However, the effect of soil on solubility, spatial distribution and speciation of ZnO nanoparticles has not yet been investigated. In this study, we examined the diffusion and solid phase speciation of Zn in an alkaline calcareous soil following application of nanoparticulate and bulk ZnO coated fertilizer products (monoammonium phosphate (MAP and urea using laboratory-based x-ray techniques and synchrotron-based μ-x-ray fluorescence (μ-XRF mapping and absorption fine structure spectroscopy (μ-XAFS. Mapping of the soil-fertilizer reaction zones revealed that most of the applied Zn for all treatments remained on the coated fertilizer granule or close to the point of application after five weeks of incubation in soil. Zinc precipitated mainly as scholzite (CaZn2(PO42.2H2O and zinc ammonium phosphate (Zn(NH4PO4 species at the surface of MAP granules. These reactions reduced dissolution and diffusion of Zn from the MAP granules. Although Zn remained as zincite (ZnO at the surface of urea granules, limited diffusion of Zn from ZnO-coated urea granules was also observed for both bulk and nanoparticulate ZnO treatments. This might be due to either the high pH of urea granules, which reduced solubility of Zn, or aggregation (due to high ionic strength of released ZnO nanoparticles around the granule/point of application. The relative proportion of Zn(OH2 and ZnCO3 species increased for all Zn treatments with increasing distance from coated MAP and urea granules in the calcareous soil. When coated on macronutrient fertilizers, Zn from ZnO nanoparticles (without surface modifiers was not more mobile or diffusible compared to bulk forms of ZnO. The results also suggest that risk associated with the presence of ZnO NPs in calcareous soils would be

  12. Fate of Zinc Oxide Nanoparticles Coated onto Macronutrient Fertilizers in an Alkaline Calcareous Soil.

    Science.gov (United States)

    Milani, Narges; Hettiarachchi, Ganga M; Kirby, Jason K; Beak, Douglas G; Stacey, Samuel P; McLaughlin, Mike J

    2015-01-01

    Zinc oxide (ZnO) nanoparticles may provide a more soluble and plant available source of Zn in Zn fertilizers due to their greater reactivity compared to equivalent micron- or millimetre-sized (bulk) particles. However, the effect of soil on solubility, spatial distribution and speciation of ZnO nanoparticles has not yet been investigated. In this study, we examined the diffusion and solid phase speciation of Zn in an alkaline calcareous soil following application of nanoparticulate and bulk ZnO coated fertilizer products (monoammonium phosphate (MAP) and urea) using laboratory-based x-ray techniques and synchrotron-based μ-x-ray fluorescence (μ-XRF) mapping and absorption fine structure spectroscopy (μ-XAFS). Mapping of the soil-fertilizer reaction zones revealed that most of the applied Zn for all treatments remained on the coated fertilizer granule or close to the point of application after five weeks of incubation in soil. Zinc precipitated mainly as scholzite (CaZn2(PO4)2.2H2O) and zinc ammonium phosphate (Zn(NH4)PO4) species at the surface of MAP granules. These reactions reduced dissolution and diffusion of Zn from the MAP granules. Although Zn remained as zincite (ZnO) at the surface of urea granules, limited diffusion of Zn from ZnO-coated urea granules was also observed for both bulk and nanoparticulate ZnO treatments. This might be due to either the high pH of urea granules, which reduced solubility of Zn, or aggregation (due to high ionic strength) of released ZnO nanoparticles around the granule/point of application. The relative proportion of Zn(OH)2 and ZnCO3 species increased for all Zn treatments with increasing distance from coated MAP and urea granules in the calcareous soil. When coated on macronutrient fertilizers, Zn from ZnO nanoparticles (without surface modifiers) was not more mobile or diffusible compared to bulk forms of ZnO. The results also suggest that risk associated with the presence of ZnO NPs in calcareous soils would be the same

  13. Export of soil macronutrients in area cultivated with maize to feeding feedlot steers

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    Robson Kyoshi Ueno

    2013-12-01

    Full Text Available The maize cultivated for forage requires special care with soil management. The nutrients exportation by silage might cause reducing of soil fertility, with consequent decrease of yield and nutritional quality of posterior crops. The aim of this work was assess levels of macronutrients in maize plant fragments (stem, leaves, bracts plus cob and grains, at stage of ensilage, in entire plant (silage forage and in the mature grains; measure the nutrients exportation from soil by forage or grains. After, two diets were used in feedlot cattle, first was based on silage and other based in grains, to appraise the potential of nutrients to return into soil by manure and the final account of nutrients balance. The levels of N, P, K, Ca and Mg from forage were, respectively: 1,37; 0,24; 0,81; 0,2 and 0,22%; and in grains: 1,8; 0,28; 0,34; 0,12; and 0,11%. The fertilization performed was enough to supply extracted nutrients when was harvested only grains, promoting deficits in soil of 93 kg ha-1 of N and 84 kg ha-1 of K when was harvested forage. The manure of animals feed with silage+concentrated, compared to diet without roughage (80% grains and 20% protein core, cycled different amounts of N (276,28 vs 59,37, P (128,12 vs 33,37, K (58,32 vs 5,38, Ca (177,7 vs 78,89 and Mg (43,64 vs 11,81 in the cultivated area. The evaluated production systems presented capacity to maintain the levels of nutrients at soil through replacement via manure, and might contribute to the enrichment of fertility and reduce costs with mineral fertilizers in successive crops. The system which forage was used presented deficit of 25 kg ha-1 de K, probably due to insufficient amount of K applied, which recommendation is frequently made to grain production.

  14. Fate of Zinc Oxide Nanoparticles Coated onto Macronutrient Fertilizers in an Alkaline Calcareous Soil

    Science.gov (United States)

    Milani, Narges; Hettiarachchi, Ganga M.; Kirby, Jason K.; Beak, Douglas G.; Stacey, Samuel P.; McLaughlin, Mike J.

    2015-01-01

    Zinc oxide (ZnO) nanoparticles may provide a more soluble and plant available source of Zn in Zn fertilizers due to their greater reactivity compared to equivalent micron- or millimetre-sized (bulk) particles. However, the effect of soil on solubility, spatial distribution and speciation of ZnO nanoparticles has not yet been investigated. In this study, we examined the diffusion and solid phase speciation of Zn in an alkaline calcareous soil following application of nanoparticulate and bulk ZnO coated fertilizer products (monoammonium phosphate (MAP) and urea) using laboratory-based x-ray techniques and synchrotron-based μ-x-ray fluorescence (μ–XRF) mapping and absorption fine structure spectroscopy (μ–XAFS). Mapping of the soil-fertilizer reaction zones revealed that most of the applied Zn for all treatments remained on the coated fertilizer granule or close to the point of application after five weeks of incubation in soil. Zinc precipitated mainly as scholzite (CaZn2(PO4)2.2H2O) and zinc ammonium phosphate (Zn(NH4)PO4) species at the surface of MAP granules. These reactions reduced dissolution and diffusion of Zn from the MAP granules. Although Zn remained as zincite (ZnO) at the surface of urea granules, limited diffusion of Zn from ZnO-coated urea granules was also observed for both bulk and nanoparticulate ZnO treatments. This might be due to either the high pH of urea granules, which reduced solubility of Zn, or aggregation (due to high ionic strength) of released ZnO nanoparticles around the granule/point of application. The relative proportion of Zn(OH)2 and ZnCO3 species increased for all Zn treatments with increasing distance from coated MAP and urea granules in the calcareous soil. When coated on macronutrient fertilizers, Zn from ZnO nanoparticles (without surface modifiers) was not more mobile or diffusible compared to bulk forms of ZnO. The results also suggest that risk associated with the presence of ZnO NPs in calcareous soils would be the

  15. Enhanced Lacto-Tri-Peptide Bio-Availability by Co-Ingestion of Macronutrients.

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    Gabriella A M Ten Have

    Full Text Available Some food-derived peptides possess bioactive properties, and may affect health positively. For example, the C-terminal lacto-tri-peptides Ile-Pro-Pro (IPP, Leu-Pro-Pro (LPP and Val-Pro-Pro (VPP (together named here XPP are described to lower blood pressure. The bioactivity depends on their availability at the site of action. Quantitative trans-organ availability/kinetic measurements will provide more insight in C-terminal tri-peptides behavior in the body. We hypothesize that the composition of the meal will modify their systemic availability. We studied trans-organ XPP fluxes in catheterized pigs (25 kg; n=10 to determine systemic and portal availability, as well as renal and hepatic uptake of a water-based single dose of synthetic XPP and a XPP containing protein matrix (casein hydrolyte, CasH. In a second experiment (n=10, we compared the CasH-containing protein matrix with a CasH-containing meal matrix and the modifying effects of macronutrients in a meal on the availability (high carbohydrates, low quality protein, high fat, and fiber. Portal availability of synthetic XPP was 0.08 ± 0.01% of intake and increased when a protein matrix was present (respectively 3.1, 1.8 and 83 times for IPP, LPP and VPP. Difference between individual XPP was probably due to release from longer peptides. CasH prolonged portal bioavailability with 18 min (absorption half-life, synthetic XPP: 15 ± 2 min, CasH: 33 ± 3 min, p<0.0001 and increased systemic elimination with 20 min (synthetic XPP: 12 ± 2 min; CasH: 32 ± 3 min, p<0.0001. Subsequent renal and hepatic uptake is about 75% of the portal release. A meal containing CasH, increased portal 1.8 and systemic bioavailability 1.2 times. Low protein quality and fiber increased XPP systemic bioavailability further (respectively 1.5 and 1.4 times. We conclude that the amount and quality of the protein, and the presence of fiber in a meal, are the main factors that increase the systemic bioavailability of food

  16. Composition and Variation of Macronutrients, Immune Proteins, and Human Milk Oligosaccharides in Human Milk From Nonprofit and Commercial Milk Banks.

    Science.gov (United States)

    Meredith-Dennis, Laura; Xu, Gege; Goonatilleke, Elisha; Lebrilla, Carlito B; Underwood, Mark A; Smilowitz, Jennifer T

    2017-06-01

    When human milk is unavailable, banked milk is recommended for feeding premature infants. Milk banks use processes to eliminate pathogens; however, variability among methods exists. Research aim: The aim of this study was to compare the macronutrient (protein, carbohydrate, fat, energy), immune-protective protein, and human milk oligosaccharide (HMO) content of human milk from three independent milk banks that use pasteurization (Holder vs. vat techniques) or retort sterilization. Randomly acquired human milk samples from three different milk banks ( n = 3 from each bank) were analyzed for macronutrient concentrations using a Fourier transform mid-infrared spectroscopy human milk analyzer. The concentrations of IgA, IgM, IgG, lactoferrin, lysozyme, α-lactalbumin, α antitrypsin, casein, and HMO were analyzed by mass spectrometry. The concentrations of protein and fat were significantly ( p milk samples that had undergone retort sterilization had significantly less immune-protective proteins and total and specific HMOs compared with samples that had undergone Holder and vat pasteurization. These data suggest that further analysis of the effect of retort sterilization on human milk components is needed prior to widespread adoption of this process.

  17. Nucleotides, micro- and macro-nutrients, limonoids, flavonoids, and hydroxycinnamates composition in the phloem sap of sweet orange.

    Science.gov (United States)

    Hijaz, Faraj; Manthey, John A; Van der Merwe, Deon; Killiny, Nabil

    2016-06-02

    Currently, the global citrus production is declining due to the spread of Huanglongbing (HLB). HLB, otherwise known as citrus greening, is caused by Candidatus Liberibacter asiaticus (CLas) and is transmitted by the Asian citrus psyllids (ACP), Diaphorina citri Kuwayama. ACP transmits CLas bacterium while feeding on the citrus phloem sap. Multiplication of CLas in the phloem of citrus indicates that the sap contains all the essential nutrients needed for CLas. In this study, we investigated the micro- and macro-nutrients, nucleotides, and others secondary metabolites of phloem sap from pineapple sweet orange. The micro- and macro-nutrients were analyzed using inductively coupled plasma-mass spectroscopy (ICP-MS) and inductively coupled plasma-optical emission spectroscopy (ICP-OES). Nucleotides and other secondary metabolites analysis was accomplished by reversed phase HPLC coupled with UV, fluorescence detection, or negative mode electrospray ionization mass spectrometry (ESI-MS). Calcium (89 mM) was the highest element followed by potassium (38.8 mM) and phosphorous (24 mM). Magnesium and sulfur were also abundant and their concentrations were 15 and 9 mM, respectively. The rest of the elements were found in low amounts (sap.

  18. Prediction of Macronutrients at the Canopy Level Using Spaceborne Imaging Spectroscopy and LiDAR Data in a Mixedwood Boreal Forest

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    Kemal Gökkaya

    2015-07-01

    Full Text Available Information on foliar macronutrients is required in order to understand plant physiological and ecosystem processes such as photosynthesis, nutrient cycling, respiration and cell wall formation. The ability to measure, model and map foliar macronutrients (nitrogen (N, phosphorus (P, potassium (K, calcium (Ca and magnesium (Mg at the forest canopy level provides information on the spatial patterns of ecosystem processes (e.g., carbon exchange and provides insight on forest condition and stress. Imaging spectroscopy (IS has been used particularly for modeling N, using airborne and satellite imagery mostly in temperate and tropical forests. However, there has been very little research conducted at these scales to model P, K, Ca, and Mg and few studies have focused on boreal forests. We report results of a study of macronutrient modeling using spaceborne IS and airborne light detection and ranging (LiDAR data for a mixedwood boreal forest canopy in northern Ontario, Canada. Models incorporating Hyperion data explained approximately 90% of the variation in canopy concentrations of N, P, and Mg; whereas the inclusion of LiDAR data significantly improved the prediction of canopy concentration of Ca (R2 = 0.80. The combined used of IS and LiDAR data significantly improved the prediction accuracy of canopy Ca and K concentration but decreased the prediction accuracy of canopy P concentration. The results indicate that the variability of macronutrient concentration due to interspecific and functional type differences at the site provides the basis for the relationship observed between the remote sensing measurements (i.e., IS and LiDAR and macronutrient concentration. Crown closure and canopy height are the structural metrics that establish the connection between macronutrient concentration and IS and LiDAR data, respectively. The spatial distribution of macronutrient concentration at the canopy scale mimics functional type distribution at the site. The

  19. High-fiber rye diet increases ileal excretion of energy and macronutrients compared with low-fiber wheat diet independent of meal frequency in ileostomy subjects

    DEFF Research Database (Denmark)

    Isaksson, Hanna; Landberg, Rikard; Sundberg, Birgitta;

    2013-01-01

    Background:Whole-grain foods and cereal dietary fiber intake is associated with lower body weight. This may partly result from lower energy utilization of high-fiber diets. Objective: In the present study, the impact on ileal excretion of energy and macronutrients in response to a rye bread high...... at the third day of each of the four dietary periods and analyzed for gross energy and nutrient contents. Results: The results showed that intake of rye bread high-fiber diet compared to the refined wheat low-fiber diet caused an increase in ileal excretion of energy and macronutrients. The effect...

  20. Maternal adjustment or constraint: differential effects of food availability on maternal deposition of macro-nutrients, steroids and thyroid hormones in rock pigeon eggs.

    Science.gov (United States)

    Hsu, Bin-Yan; Dijkstra, Cor; Darras, Veerle M; de Vries, Bonnie; Groothuis, Ton G G

    2016-01-01

    In oviparous species like birds, eggs provide the direct environment in which embryos are developing. Mothers may adjust different egg components in different ways in reaction to environmental cues either to adjust offspring development or because of constraints. In this study, we investigated the effects of food quality and quantity before and during egg laying on three different aspects of egg quality: macro-nutrients (egg and yolk mass), androgens (testosterone and androstenedione), and thyroid hormones (3,5,3'-triiodothyronine, T3 and l-thyroxine, T4), using the rock pigeon (Columba livia). As expected, egg and yolk mass were significantly reduced for the eggs laid under the poor-food condition, indicating a maternal trade-off between offspring and self in allocating important resources. We did not find any significant change in yolk testosterone or their within-clutch pattern over the laying sequence. This is consistent with the fact that, in contrast with nutrients, these hormones are not costly to produce, but does not support the hypothesis that they play a role in adjusting brood size to food conditions. In contrast, we found that T3 levels were higher in the egg yolks under the poor-food condition whereas the total T4 content was lower. This change could be related to the fact that iodine, the critical constituent of thyroid hormones, might be a limiting factor in the production of this hormone. Given the knowledge that food restriction usually lead to reduction of circulating T3 levels, our results suggested that avian mothers can independently regulate its concentrations in their eggs from their own circulation. The study demonstrates that environmentally induced maternal effects via the egg can be a result of a combination of constrained resources and unconstrained signals and that thyroid hormones might be an interesting case of both. Therefore, this hormone and the interplay of different maternal effects on the offspring phenotype deserve much more

  1. Deficiências de macronutrientes em sorgo The macronutrients deficiency in sorghum

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    Adalberto Santi

    2006-04-01

    Full Text Available A procura de informações sobre sorgo tem aumentado e parece estar associada ao seu maior potencial produtivo, maior resistência ao déficit hídrico, o surgimento de novas cultivares e expansão do seu cultivo na região do Cerrado. Com base nisso, objetivou-se com o presente trabalho verificar os sintomas típicos e individualizados de deficiência nutricional de macronutrientes na cultura do sorgo, mediante a observação dos efeitos da omissão de nutrientes no desenvolvimento das plantas e avaliar os efeitos dessas omissões na composição mineral do sorgo. Foram cultivadas plantas de sorgo em solução nutritiva completa de Sarruge (1975, submetidas aos seguintes tratamentos: omissão de N, P, K, Ca, Mg e S. Aos dois dias após o início do ensaio, as plantas apresentaram os primeiros indícios de deficiência, que foram descritos e caracterizados. Quando os sintomas estavam definidos as plantas foram coletadas, lavadas, separadas em folhas, colmo e raízes, colocadas para secar, para posterior determinação de massa seca, área foliar e teores de macronutrientes. Os sintomas visuais de deficiência de nutrientes mostraram-se de uma maneira geral facilmente caracterizáveis. A produção de massa seca foi afetada pela omissão de nutrientes e os tratamentos que mais afetaram as diferentes partes das plantas e as áreas foliares foram as omissões de nitrogênio, cálcio e magnésio. O acúmulo de nutrientes pelas plantas obedeceu a seguinte ordem decrescente: N>K>Ca>Mg>P>S.The searching for information about sorghum is increasing and seems to be connected to a greater pontential of productivity, greater resistance to hydro deficit, the forthcoming of new cultivate with good characteristics for the grain production and expansion of its culture in the bushy region. Based on this, the objectives of this work was to verify the typical symptoms and the unique nutritional differences of macronutrients in the sorghum cultivate, by observation

  2. Asymbiotic culture of Cattleya intermedia Graham (Orchidaceae: the influence of macronutrient salts and sucrose concentrations on survival and development of plantlets

    Directory of Open Access Journals (Sweden)

    Márcio Hisayuki Sasamori

    2015-09-01

    Full Text Available ABSTRACTCattleya intermediais an Atlantic Forest species endemic to Brazil that is classed as vulnerable on the list of threatened species. In this study, C. intermedia plantlets were micropropagated in an asymbiotic culture and the influence of different concentrations of sucrose (15, 30, 45 and 60 g L-1, plus a zero sucrose medium and macronutrient salts (complete Murashige and Skoog (MS medium and half MS medium (with half-strength macronutrients on survival and development of the plantlets was evaluated. In all treatments 100% plantlet survival was achieved. The integrated analysis of height of aerial part, number of leaves per plantlet, fresh mass, number of roots per plantlet and length of the longest root showed that the plantlets exhibited greatest development at the half-strength macronutrient concentrations with 45 or 60 g L-1 of sucrose, as well as at the complete macronutrient concentration with 60 g L-1 of sucrose. Plantlets acclimatized and reintroduced to an environment in which the species occurs naturally exhibited 98.6% survival. The results obtained in this study allowed the establishment of optimal conditions for asymbiotic micropropagation, which is a requisite for future studies focused on conservation of C. intermedia.

  3. Ion Chromatography as an Alternative to Standard Methods for Analysis of Macro-nutrients in Mehlich 1 Extracts of Unfertilized Forest Soils

    Science.gov (United States)

    Joseph B. Fischer; James H. Miller

    2004-01-01

    This study evaluates ion chromatography (IC) as an alternative to atomic absorption (AA) and inductively-coupled plasma spectromctry (ICP) for analysis of potassium (K), magnesium (Mg), and calcium (Ca), and and as an alternative to antimonylmolybdate colorimetry and ICP for analysis of phosphorus (P) macro-nutrients in Mehlich 1 extracts. Soils typical of pine forests...

  4. Macronutrient Intakes in 553 Dutch Elite and Sub-Elite Endurance, Team, and Strength Athletes: Does Intake Differ between Sport Disciplines?

    NARCIS (Netherlands)

    Wardenaar, Floris; Brinkmans, Naomi; Ceelen, Ingrid; Rooij, Van Bo; Mensink, Marco; Witkamp, Renger; Vries, De Jeanne

    2017-01-01

    Web-based 24-h dietary recalls and questionnaires were obtained from 553 Dutch well-trained athletes. The total energy and macronutrient intake was compared between discipline-categories (endurance, team, and strength) within gender, and dietary inadequacy, i.e., too low or high intakes, according

  5. Does increased exercise or physical activity alter ad-libitum daily energy intake or macronutrient composition in healthy adults? A systematic review.

    Directory of Open Access Journals (Sweden)

    Joseph E Donnelly

    Full Text Available BACKGROUND: The magnitude of the negative energy balance induced by exercise may be reduced due to compensatory increases in energy intake. OBJECTIVE: TO ADDRESS THE QUESTION: Does increased exercise or physical activity alter ad-libitum daily energy intake or macronutrient composition in healthy adults? DATA SOURCES: PubMed and Embase were searched (January 1990-January 2013 for studies that presented data on energy and/or macronutrient intake by level of exercise, physical activity or change in response to exercise. Ninety-nine articles (103 studies were included. STUDY ELIGIBILITY CRITERIA: Primary source articles published in English in peer-reviewed journals. Articles that presented data on energy and/or macronutrient intake by level of exercise or physical activity or changes in energy or macronutrient intake in response to acute exercise or exercise training in healthy (non-athlete adults (mean age 18-64 years. STUDY APPRAISAL AND SYNTHESIS METHODS: Articles were grouped by study design: cross-sectional, acute/short term, non-randomized, and randomized trials. Considerable heterogeneity existed within study groups for several important study parameters, therefore a meta-analysis was considered inappropriate. Results were synthesized and presented by study design. RESULTS: No effect of physical activity, exercise or exercise training on energy intake was shown in 59% of cross-sectional studies (n = 17, 69% of acute (n = 40, 50% of short-term (n = 10, 92% of non-randomized (n = 12 and 75% of randomized trials (n = 24. Ninety-four percent of acute, 57% of short-term, 100% of non-randomized and 74% of randomized trials found no effect of exercise on macronutrient intake. Forty-six percent of cross-sectional trials found lower fat intake with increased physical activity. LIMITATIONS: The literature is limited by the lack of adequately powered trials of sufficient duration, which have prescribed and measured exercise energy expenditure, or

  6. Effects of macronutrient composition and cyclooxygenase-inhibition on diet-induced obesity, low grade inflammation and glucose homeostasis

    DEFF Research Database (Denmark)

    Fjære, Even

    Background: Obesity and its related metabolic complications are an increasing problem worldwide. A high fat diet in combination with sucrose has been shown to induce obesity and development of glucose intolerance and insulin resistance in rodents. C57BL/6J mice were fed high fat diets with sucrose......- or protein based background, and supplemented with either corn- or fish oil. These experiments were conducted to determine whether macronutrient composition and type of dietary fat can modulate diet-induced obesity, and associated metabolic consequences. The use of non-steroidal anti-inflammatory drugs...... is escalating, and in view of the increased consumption of obesogenic diets with high levels of dietary carbohydrates and fat, the metabolic consequences of cyclooxygenase-inhibition warrants investigation. Results: High fat/high sucrose diets increased obesity development and expression of macrophage...

  7. Breakfast Macronutrient Composition Influences Thermic Effect of Feeding and Fat Oxidation in Young Women Who Habitually Skip Breakfast.

    Science.gov (United States)

    Neumann, Brianna L; Dunn, Amy; Johnson, Dallas; Adams, J D; Baum, Jamie I

    2016-08-10

    The purpose of this study was to determine if breakfast macronutrient composition improved thermic effect of feeding (TEF) and appetite after a one-week adaptation in young women who habitually skip breakfast. A randomized, controlled study was conducted in females (24.1 ± 2 years), who skip breakfast (≥5 times/week). Participants were placed into one of three groups for eight days (n = 8 per group): breakfast skipping (SKP; no breakfast), carbohydrate (CHO; 351 kcal; 59 g CHO, 10 g PRO, 8 g fat) or protein (PRO; 350 kcal; 39 g CHO, 30 g PRO, 8 g fat). On days 1 (D1) and 8 (D8), TEF, substrate oxidation, appetite and blood glucose were measured. PRO had higher (p breakfast on appetite response. In addition, CHO had a significant increase (p breakfast for 8 days increased TEF compared to CHO and SKP, while consumption of CHO for one week increased PP hunger response.

  8. A systematic review and meta-analysis of energy and macronutrient intake responses to physical activity interventions in children and adolescents with obesity.

    Science.gov (United States)

    Schwartz, C; King, N A; Perreira, B; Blundell, J E; Thivel, D

    2017-06-01

    The effects of regular physical activity on energy intake in obese adolescents are unknown. The objective is to determine how physical activity interventions affect energy and macronutrient intake in overweight/obese youth. Databases were searched from December 2014 to December 2015 for studies that measured energy and/or macronutrient consumption in response to physical activity intervention in overweight/obese youth. The review comprises primary source articles published in English in peer-reviewed journals. Articles that presented data on energy and/or macronutrient intake before and after a physical activity intervention (without dietary restriction) in overweight or obese children and teenagers (up to 18 years old) were included. Of the initial 307 references found, nine were included. The nine included studies analysed the effect of 15 different physical activity interventions. Nine showed a decrease and six unchanged energy intakes. The effect size for total energy intake ranged from -2.108 to -0.207 (n = 14). Results of the meta-analysis revealed a mean effect of physical intervention to reduce intake of -1.003 (95% confidence interval = -1.261 to -0.745, p energy intake reduction was -323 ± 286 kcal. Macronutrient intake was assessed in 11 interventions. Protein intake was found decreased in five (reduction of -26.8 ± 19.2 g), seven reported fat decrease (reduction of -26.4 ± 17.8 g) and five a decrease in CHO (reduction of -72.5 ± 22.8 g). The meta-analysis revealed significant decreases of each macronutrient (p energy intake in obese adolescents. © 2016 World Obesity Federation.

  9. Relevance of Morning and Evening Energy and Macronutrient Intake during Childhood for Body Composition in Early Adolescence

    Directory of Open Access Journals (Sweden)

    Tanja Diederichs

    2016-11-01

    Full Text Available (1 Background: This study investigated the relevance of morning and evening energy and macronutrient intake during childhood for body composition in early adolescence; (2 Methods: Analyses were based on data from 372 DONALD (DOrtmund Nutritional and Anthropometric Longitudinally Designed study participants. Explorative life-course plots were performed to examine whether morning or evening energy and macronutrient intake at 3/4 years, 5/6 years, or 7/8 years is critical for fat mass index (FMI [kg/m2] and fat free mass index (FFMI [kg/m2] in early adolescence (10/11 years. Subsequently, exposures in periods identified as consistently critical were examined in depth using adjusted regression models; (3 Results: Life-course plots identified morning fat and carbohydrate (CHO intake at 3/4 years and 7/8 years as well as changes in these intakes between 3/4 years and 7/8 years as potentially critical for FMI at 10/11 years. Adjusted regression models corroborated higher FMI values at 10/11 years among those who had consumed less fat (p = 0.01 and more CHO (p = 0.01 in the morning at 7/8 years as well as among those who had decreased their morning fat intake (p = 0.02 and increased their morning CHO intake (p = 0.05 between 3/4 years and 7/8 years; (4 Conclusion: During childhood, adherence to a low fat, high CHO intake in the morning may have unfavorable consequences for FMI in early adolescence.

  10. Energy and macronutrient intake and risk of differentiated thyroid carcinoma in the European Prospective Investigation into Cancer and Nutrition study.

    Science.gov (United States)

    Zamora-Ros, Raul; Rinaldi, Sabina; Tsilidis, Konstantinos K; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Rostgaard-Hansen, Agnetha Linn; Tjønneland, Anne; Clavel-Chapelon, Françoise; Mesrine, Sylvie; Katzke, Verena A; Kühn, Tilman; Förster, Jana; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Klinaki, Eleni; Masala, Giovanna; Sieri, Sabina; Ricceri, Fulvio; Tumino, Rosario; Mattiello, Amalia; Peeters, Petra H M; Bueno-de-Mesquita, H B As; Engeset, Dagrun; Skeie, Guri; Argüelles, Marcial; Agudo, Antonio; Sánchez, María-José; Chirlaque, María-Dolores; Barricarte, Aurelio; Chamosa, Saioa; Almquist, Martin; Tosovic, Ada; Hennings, Joakim; Sandström, Maria; Schmidt, Julie A; Khaw, Kay-Thee; Wareham, Nicholas J; Cross, Amanda J; Slimani, Nadia; Byrnes, Graham; Romieu, Isabelle; Riboli, Elio; Franceschi, Silvia

    2016-01-01

    Incidence rates of differentiated thyroid carcinoma (TC) have increased in many countries. Adiposity and dietary risk factors may play a role, but little is known on the influence of energy intake and macronutrient composition. The aim of this study was to investigate the associations between TC and the intake of energy, macronutrients, glycemic index (GI) and glycemic load in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. The study included 477,274 middle-age participants (70.2% women) from ten European countries. Dietary data were collected using country-specific validated dietary questionnaires. Total carbohydrates, proteins, fats, saturated, monounsaturated and polyunsaturated fats (PUFA), starch, sugar, and fiber were computed as g/1,000 kcal. Multivariable Cox regression was used to calculate multivariable adjusted hazard ratios (HR) and 95% confidence interval (CI) by intake quartile (Q). After a mean follow-up time of 11 years, differentiated TC was diagnosed in 556 participants (90% women). Overall, we found significant associations only with total energy (HRQ4 vs .Q1 , 1.29; 95% CI, 1.00-1.68) and PUFA intakes (HRQ4 vs .Q1 , 0.74; 95% CI, 0.57-0.95). However, the associations with starch and sugar intake and GI were significantly heterogeneous across body mass index (BMI) groups, i.e., positive associations with starch and GI were found in participants with a BMI ≥ 25 and with sugar intake in those with BMI < 25. Moreover, inverse associations with starch and GI were observed in subjects with BMI < 25. In conclusion, our results suggest that high total energy and low PUFA intakes may increase the risk of differentiated TC. Positive associations with starch intake and GI in participants with BMI ≥ 25 suggest that those persons may have a greater insulin response to high starch intake and GI than lean people.

  11. Energy and macronutrient intake and dietary pattern among school children in Bahrain: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Rasheed Parveen

    2011-06-01

    Full Text Available Abstract Background Obesity is increasing in Bahrain and there is lack of information on the energy and macronutrient intake of children. The objective of this research was to study the energy and macronutrient intake as well as food frequency pattern of Bahraini school children. Methods This is a cross-sectional descriptive study conducted on Bahraini school boys and girls aged 6-18 years from all the 11 populated regions of the country. Data on food intake consisted of a 24-hour dietary recall and was obtained by interviewing a sub-sample of the study population. Information was also obtained through a self-administered questionnaire for the entire sample on the weekly frequency of food items that were grouped into 7 categories based on similarity of nutrient profiles. Dietary analysis was performed using the Nutritionist 5 (First Data Bank Version 1.6 1998. Results While the average energy intake of students was close to the Estimated Average Requirements of the UK Reference standards, protein intake substantially exceeded the Reference Nutrient Intake values as did daily sugar consumption. Dietary fiber fell short of the Dietary Recommended Values (UK and 36%-50% students exceeded the Energy % limits for total fat, saturated fat and cholesterol. The Polyunsaturated: Saturated fat ratio remained at an unacceptable level of 0.6 for girls and boys. While sweets, snacks and regular soda drinks were popular, milk, fruits and vegetables were not commonly consumed. Conclusions High sugar consumption, low intake of dietary fiber and high energy % of saturated fat and dietary cholesterol by many Bahraini children, is likely to increase their risk of obesity and cardiovascular diseases in later life. Nutrition education programs in schools should emphasize the importance of healthy balanced diets for growth and health maintenance of children as well as dietary prevention of diseases.

  12. Absorption of macronutrients and nitrogen balance in children with dysentery fed an amylase-treated energy-dense porridge.

    Science.gov (United States)

    Rahman, M M; Mahalanabis, D; Ali, M; Mazumder, R N; Wahed, M A; Fuchs, G J

    1997-12-01

    The aim of this study was to determine the absorption of macronutrients and energy from an energy-dense diet liquefied with amylase from germinated wheat (ARF) in children suffering from acute dysentery. Thirty male children aged 6-35 months presenting with acute dysentery were randomly assigned to receive either an ARF-treated porridge or a standard porridge liquefied with water to make its consistency similar to the ARF porridge. After 24-h stabilization a 72-h metabolic balance was performed. Sixteen children received an ARF-treated porridge and 14 received a standard porridge liquefied with water. The mean +/- SD coefficients of absorption (%) of carbohydrate, fat, protein and energy (ARF porridge vs regular porridge) were 81.4 +/- 11 vs 86.9 +/- 7, 86.1 +/- 10 vs 82.8 +/- 15, 57.3 +/- 12 vs 48.4 +/- 24 and 81.4 +/- 9 vs 83.1 +/- 8, respectively. The stool loss of carbohydrate, protein, fat and energy was similar in the two groups. The net absorption of energy was substantially greater in the ARF-fed than regular porridge-fed children (by 28%, p = 0.01). The nitrogen balance was 6.9 +/- 3.4 mg kg(-1) d(-1) in the ARF porridge group and 1.1 +/- 6.7 mg kg(-1) d(-1) in the regular porridge group (p = 0.01). These results show that, despite being hyperosmolar, an amylase-treated liquefied energy-dense porridge is absorbed as well as a regular porridge by malnourished children with severe dysentery. Consequently, its use substantially increased the absorption of a net amount of macronutrients and resulted in a better nitrogen balance. These results further support this innovative approach of feeding sick children in developing countries.

  13. Amount of Macronutrients and Micronutrients in Petiole of Some Iranian and Imported Grape Cultivars

    Directory of Open Access Journals (Sweden)

    H. Doulati Baneh

    2016-02-01

    Full Text Available Introduction: Grapevine (Vitis vinifera L. is one of the oldest and most important perennial crops in the world. Several native grapevine genotypes, highly appreciated for their organoleptic characteristics and commercial potential are still cultivated in Iran. Developing viticulture requires the conservation of autochthonous varieties that have evolved several mechanisms enabling them to cope with the local bioclimatic and edaphic conditions. Nutrition is a key component of vineyard management that has the potential to influence various factors in vine production that includes fruit set and quality. To develop suitable nutrient plant growers need to have an understanding of the factors such as cultivars, rootstocks, soil type, irrigation type and nutrients that they are applying in the vineyard. The uptake of nutrients from the soil depends on different factors namely; their soluble content in it, soil pH, plant growth stage, plant genetics and types of soil and fertilizers. Plant species have a variety of capacities in removing and accumulating elements. Vigorous genotypes are more capable of finding the necessary nutrients from the surrounding soil environment. This indicates that it does not require as much nutrient as poor vigor genotypes. So, for sustainable viticulture, it is important to know the interactive influences of cultivars, soil characters, climatic conditions, and irrigation type on vine productivity. Materials and Methods: To evaluate and compare the amount of macronutrient elements (N, P, K, Mg and Ca and micronutrient elements (B, Zn and Mn in petiole of some Iranian grapevine cultivars including Bidanesefid Qazvin- Peikany Kashmar- Khalili Shiraz-Rasha and four foreign cultivars Thompson seedless, Flame seedless, Perlette and Black seedless,This study was carried out as –randomized complete blocks design -with-four replications in the Kahriz Horticulture Research station -.A total of 30 adult leaves per cultivar were

  14. Influence of pork and pork by-products on macronutrient and energy digestibility and palatability in large exotic felids.

    Science.gov (United States)

    Iske, C J; Morris, C L; Kappen, K L

    2016-09-01

    Two experiments were conducted to evaluate digestibility and palatability of a new commercial pork-based raw diet for zoo-managed felids. Currently 2 protein sources (beef or horse) comprise the majority of commercial raw meat diet formulations for exotic carnivores in zoological institutions. Pork-based diets have traditionally not been widely utilized and thus nutrient digestibility of pork has not been adequately evaluated in exotic carnivores. The objectives of this study were 1) to determine if a pork-based diet had similar apparent total tract macronutrient digestibility and fecal scores as standard zoo carnivore diets formulated with either horse or beef, in large exotic felids and 2) evaluate palatability of pork for use in zoos. Ten exotic felids were used including cheetahs (; 3), jaguars (; = 3), leopards (; 2), puma (; 1), and Bengal tiger (; 1). Dietary treatments consisted of 4 raw meat diets: 1 horse-based (Horse), 2 beef-based (B1, B2), and 1 pork-based diet (Pork). Fecal scores also were evaluated (1 = hard to 5 = watery/liquid). This randomized crossover design study consisted of 4 periods, each 10 d for treatment adaptation followed by 4 d of sample collection. Dry matter and crude protein apparent digestibility values were greater ( matter digestibility was greater ( < 0.05) in felids fed Pork (90.8%) than felids fed Horse (88.5%). Apparent fat digestibility values were high across all treatments but were greater ( < 0.05) in felids fed Pork (98.5%) compared with felids fed B1 (95.5%) or B2 (96.5%). Gross energy digestibility values were greater in felids fed Pork (92.4%) compared with B1 (90.2%). Average fecal scores were 2.30, 2.94, 3.42, and 3.54 for Horse, Pork, B1 and B2, respectively; and were different ( < 0.05) between treatments with exception of B1 and B2 that did not differ. Felids approached the pork diet first in 65.6% of observations and tasted the pork diet first in 71.9% of observations, compared with a beef-based raw diet. Based

  15. Effect of fermentation of cereals on the degradation of polysaccharides and other macronutrients in the gastrointestinal tract of growing pigs.

    Science.gov (United States)

    Sholly, D M; Jørgensen, H; Sutton, A L; Richert, B T; Bach Knudsen, K E

    2011-07-01

    The main objective of the present investigation was to study the impact of fermentation of cereals on the degradation of polysaccharides and other macronutrients in the small intestine and total tract of growing pigs. Eight pigs (initial BW, 34.5 ± 0.9 kg) were used in a replicated 4 × 4 Latin square design. Pigs were cannulated and housed individually in metabolism pens during sample collection. The 4 cereal-based diets were nonfermented liquid barley (NFLB), nonfermented liquid wheat (NFLW), fermented liquid barley (FLB), and fermented liquid wheat (FLW). The fermented feeds were prepared by storing the dietary cereals (barley and wheat) and water [1:2.75 (wt/wt)] in a closed tank at 25 °C for 2 d, after which 50% of the volume was removed and replaced with an equal amount of fresh cereals and water after each afternoon meal. At the time of feeding (0730 and 1430 h), the remaining dietary ingredients were added. Water was added to the dry nonfermented feeds [1:1 (wt/wt)] immediately before feeding. The fermentation process reduced the amount of DM in both cereals (Pfermented cereals. There was an interaction of cereal and treatment for ileal flow of DM (P=0.014), OM (P=0.013), and protein (P=0.006), which were less in pigs fed the NFLB than the FLB diets, but unchanged in pigs fed the NFLW and FLW diets. Conversely, the ileal flow of protein was similar (P=0.605) in pigs fed the barley diets (average, 47.5 ± 1.7 g/kg of DMI) and increased with the FLW diet compared with the NFLW diet (43 vs. 35 g/kg of DMI, respectively). Ileal fat and CH(2)O digestibilities were 7.6 (P=0.002) and 8.9% (Pfermented than nonfermented diets (86.5 vs. 84.5%, respectively; PFermentation reduced (PFermentation had no effect (P=0.243) on the fecal digestibility of nonstarch polysaccharides in either of the cereals but their digestibility was 10.0% greater (Pfermentation of cereal before feeding altered the dietary composition and influenced flow and composition of polysaccharides

  16. Effect of macronutrients and fiber on postprandial glycemic responses and meal glycemic index and glycemic load value determinations.

    Science.gov (United States)

    Meng, Huicui; Matthan, Nirupa R; Ausman, Lynne M; Lichtenstein, Alice H

    2017-02-15

    Background: The potential confounding effect of different amounts and proportions of macronutrients across eating patterns on meal or dietary glycemic index (GI) and glycemic load (GL) value determinations has remained partially unaddressed.Objective: The study aimed to determine the effects of different amounts of macronutrients and fiber on measured meal GI and GL values.Design: Four studies were conducted during which participants [n = 20-22; women: 50%; age: 50-80 y; body mass index (in kg/m(2)): 25-30)] received food challenges containing different amounts of the variable nutrient in a random order. Added to the standard 50 g available carbohydrate from white bread was 12.5, 25, or 50 g carbohydrate; 12.5, 25, or 50 g protein; and 5.6, 11.1, or 22.2 g fat from rice cereal, tuna, and unsalted butter, respectively, and 4.8 or 9.6 g fiber from oat cereal. Arterialized venous blood was sampled for 2 h, and measured meal GI and GL and insulin index (II) values were calculated by using the incremental area under the curve (AUCi) method.Results: Adding carbohydrate to the standard white-bread challenge increased glucose AUCi (P < 0.0001), measured meal GI (P = 0.0066), and mean GL (P < 0.0001). Adding protein (50 g only) decreased glucose AUCi (P = 0.0026), measured meal GI (P = 0.0139), and meal GL (P = 0.0140). Adding fat or fiber had no significant effect on these variables. Adding carbohydrate (50 g), protein (50 g), and fat (11.1 g) increased the insulin AUCi or II; fiber had no effect.Conclusions: These data indicate that uncertainty in the determination of meal GI and GL values is introduced when carbohydrate-containing foods are consumed concurrently with protein (equal amount of carbohydrate challenge) but not with carbohydrate-, fat-, or fiber-containing foods. Future studies are needed to evaluate whether this uncertainty also influences the prediction of average dietary GI and GL values for eating patterns. This trial was registered at clinicaltrials

  17. Macronutrient digestibility, nitrogen balance, plasma indicators of protein metabolism and mineral absorption in horses fed a ration rich in sugar beet pulp.

    Science.gov (United States)

    Olsman, A F S; Huurdeman, C M; Jansen, W L; Haaksma, J; Sloet van Oldruitenborgh-Oosterbaan, M M; Beynen, A C

    2004-10-01

    In a cross-over study with six mature horses, the effect of iso-energetic replacement of dietary glucose by beet pulp on macronutrient digestibility, nitrogen metabolism and mineral absorption was studied. The test ration contained 25% beet pulp in the total dietary dry matter. Beet pulp feeding significantly lowered crude fat and non-structural carbohydrate digestibility, but had no significant effect on digestibility of other macronutrients, faecal and urinary nitrogen excretion and the faecal to urinary nitrogen excretion quotient. However, on the beet pulp diet, plasma ammonia and creatinin concentrations were significantly lower than on the glucose diet. No diet effect on magnesium absorption was observed. It is suggested that dietary beet pulp stimulates the conversion of ammonia into urea.

  18. The excesive intake of macronutrients: does it influence the sportive performances of young cyclists? La excesiva ingesta de macronutrientes: ¿influye en el rendimiento deportivo de jóvenes ciclistas?

    OpenAIRE

    J. L. Sánchez-Benito; E. Sánchez Soriano

    2007-01-01

    The purpose was to determine whether 34 young Spanish males belonging to a cyclist team, follows the optimal macronutrients intake based on the ecommended dietary guidelines. The deficits in nutrition jeopardise the sportive performances, but what about the diets with excessive intake of macronutrients? Furthermore, is there an association between their sportive achievements and the psychological profile? Surely, but the problem is to determine which psychological variables are involved. Meth...

  19. The Effects of a Normal Rate versus a Slow Intervalled Rate of Oral Nutrient Intake and Intravenous Low Rate Macronutrient Application on Psychophysical Function – Two Pilot Studies

    Science.gov (United States)

    Denzer-Lippmann, Melanie Y.; Bachlechner, Stephan; Wielopolski, Jan; Fischer, Marie; Buettner, Andrea; Doerfler, Arndt; Schöfl, Christof; Münch, Gerald; Kornhuber, Johannes; Thürauf, Norbert

    2017-01-01

    Stomach distension and energy per time are factors influencing satiety. Moreover, different rates of nutrient intake induce different stomach distension. The goal of our studies was to elucidate the influence of different oral rates of nutrient intake (normal rate versus slow intervalled rate; study I) and intravenous low rate macronutrient application (protein, carbohydrate, fat) or placebo (study II) on psychophysical function. The pilot studies investigated the effects of 1) study I: a mixed nutrient solution (1/3 protein, 1/3 fat, 1/3 carbohydrates) 2) study II: intravenous macronutrient infusions (protein, carbohydrate, fat) or placebo on psychophysical function (mood, hunger, food craving, alertness, smell intensity ratings and hedonic ratings) in human subjects. In study I 10 male subjects (age range: 21–30 years) completed the study protocol participating in both test conditions and in study II 20 male subjects (age range: 19–41 years) completed the study protocol participating in all test conditions. Additionally, metabolic function was analyzed and cognitive and olfactory tests were conducted twice starting 100 min before the beginning of the intervention and 240 min after. Psychophysical (mood, hunger, fat-, protein-, carbohydrate-, sweets- and vegetable-craving), alertness and metabolic function tests were performed seven times on each examination day. Greater effects on hunger and food cravings were observed for normal rate of intake compared to slow intervalled rate of intake and intravenous low rate macronutrient application. Our findings potentially confirm that volume of the food ingested and a higher rate of energy per time contribute to satiety during normal rate of food intake, while slow intervalled rate of food intake and intravenous low rate macronutrient application showed no effects on satiation. Our results motivate the view that a certain amount of volume of the food ingested and a certain energy per time ratio are necessary to reduce

  20. Rationale and design of a study using a standardized locally procured macronutrient supplement as adjunctive therapy to HIV treatment in Kenya.

    Science.gov (United States)

    Sztam, Kevin A; Ndirangu, Murugi; Sheriff, Muhsin; Arpadi, Stephen M; Hawken, Mark; Rashid, Juma; Deckelbaum, Richard J; El Sadr, Wafaa M

    2013-01-01

    Poor nutritional status at initiation of antiretroviral therapy (ART) is predictive of mortality. Decreased dietary intake is a major determinant of weight loss in HIV. Despite a biological rationale to treat undernutrition in adults receiving ART, few studies have provided data on feasibility, safety, effectiveness, and sustainability of specific macronutrient supplements with HIV treatment in adults, especially supplements such as a food basket, a supplement approach seldom evaluated in spite of its wide use. We present the rationale and design for a study of a locally procured macronutrient supplement given to HIV-infected patients initiating ART with a body mass index (BMI) ≤20.0 kg/m(2). The objective was to determine feasibility of procurement, distribution, safety and to obtain preliminary effectiveness data for a locally procured supplement. The design was a comparative study for 200 adult participants at two Kenya government-supported clinics. The primary outcome was BMI at 24 weeks. Supplement duration was 24 weeks, total follow-up was 48 weeks, and the study included a comparison site. Novel aspects of this study include use of a standardized macronutrient supplement to protect the participant against household food sharing, and a complementary micronutrient supplement. Comprehensive data collected included dietary intake, HIV-related quality-of-life, food security, neuropsychiatric assessments, laboratory studies, and household geomapping. Assessments were made at baseline, at 24 weeks, and at 48 weeks post-ART initiation. Challenges included establishing a partnership with local millers, distribution from the HIV clinic, food safety, and tracking of participants. These findings will help inform nutrition support programming in Kenya and similar settings, and provide needed data regarding use of macronutrient supplements as an adjunctive intervention with ART.

  1. Associations of body mass index and waist circumference with: energy intake and percentage energy from macronutrients, in a cohort of australian children

    Directory of Open Access Journals (Sweden)

    Abbott Rebecca A

    2011-05-01

    Full Text Available Abstract Background It is evident from previous research that the role of dietary composition in relation to the development of childhood obesity remains inconclusive. Several studies investigating the relationship between body mass index (BMI, waist circumference (WC and/or skin fold measurements with energy intake have suggested that the macronutrient composition of the diet (protein, carbohydrate, fat may play an important contributing role to obesity in childhood as it does in adults. This study investigated the possible relationship between BMI and WC with energy intake and percentage energy intake from macronutrients in Australian children and adolescents. Methods Height, weight and WC measurements, along with 24 h food and drink records (FDR intake data were collected from 2460 boys and girls aged 5-17 years living in the state of Queensland, Australia. Results Statistically significant, yet weak correlations between BMI z-score and WC with total energy intake were observed in grades 1, 5 and 10, with only 55% of subjects having a physiologically plausible 24 hr FDR. Using Pearson correlations to examine the relationship between BMI and WC with energy intake and percentage macronutrient intake, no significant correlations were observed between BMI z-score or WC and percentage energy intake from protein, carbohydrate or fat. One way ANOVAs showed that although those with a higher BMI z-score or WC consumed significantly more energy than their lean counterparts. Conclusion No evidence of an association between percentage macronutrient intake and BMI or WC was found. Evidently, more robust longitudinal studies are needed to elucidate the relationship linking obesity and dietary intake.

  2. The Effects of a Normal Rate versus a Slow Intervalled Rate of Oral Nutrient Intake and Intravenous Low Rate Macronutrient Application on Psychophysical Function – Two Pilot Studies

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    Melanie Y. Denzer-Lippmann

    2017-06-01

    Full Text Available Stomach distension and energy per time are factors influencing satiety. Moreover, different rates of nutrient intake induce different stomach distension. The goal of our studies was to elucidate the influence of different oral rates of nutrient intake (normal rate versus slow intervalled rate; study I and intravenous low rate macronutrient application (protein, carbohydrate, fat or placebo (study II on psychophysical function. The pilot studies investigated the effects of 1 study I: a mixed nutrient solution (1/3 protein, 1/3 fat, 1/3 carbohydrates 2 study II: intravenous macronutrient infusions (protein, carbohydrate, fat or placebo on psychophysical function (mood, hunger, food craving, alertness, smell intensity ratings and hedonic ratings in human subjects. In study I 10 male subjects (age range: 21–30 years completed the study protocol participating in both test conditions and in study II 20 male subjects (age range: 19–41 years completed the study protocol participating in all test conditions. Additionally, metabolic function was analyzed and cognitive and olfactory tests were conducted twice starting 100 min before the beginning of the intervention and 240 min after. Psychophysical (mood, hunger, fat-, protein-, carbohydrate-, sweets- and vegetable-craving, alertness and metabolic function tests were performed seven times on each examination day. Greater effects on hunger and food cravings were observed for normal rate of intake compared to slow intervalled rate of intake and intravenous low rate macronutrient application. Our findings potentially confirm that volume of the food ingested and a higher rate of energy per time contribute to satiety during normal rate of food intake, while slow intervalled rate of food intake and intravenous low rate macronutrient application showed no effects on satiation. Our results motivate the view that a certain amount of volume of the food ingested and a certain energy per time ratio are necessary

  3. Sodium co-limits and catalyzes macronutrients in a prairie food web

    DEFF Research Database (Denmark)

    Kaspari, Michael; Roeder, Karl A.; Benson, Brittany

    2017-01-01

    Nitrogen and phosphorus frequently limit terrestrial plant production, but have a mixed record in regulating the abundance of terrestrial invertebrates. We contrasted four ways that Na could interact with an NP fertilizer to shape the plants and invertebrates of an inland prairie. We applied NP a......, and with inputs like urine. The co-limitation and catalysis of N and P by Na thus has the potential for predicting patterns of abundance and diversity across spatial scales. This article is protected by copyright. All rights reserved....

  4. Body Composition and Energy Expenditure Predict Ad-Libitum Food and Macronutrient Intake in Humans

    OpenAIRE

    Weise, Christopher M.; Hohenadel, Maximilian G.; Krakoff, Jonathan; Votruba, Susanne B.

    2013-01-01

    Background Obesity is the result of chronic positive energy balance. The mechanisms underlying the regulation of energy homeostasis and food intake are not understood. Despite large increases in fat mass (FM), recent evidence indicates that fat-free mass (FFM) rather than FM is positively associated with intake in humans. Methods In 184 humans (73F/111M; age 34.5±8.8y; % body fat [PFAT] 31.6±8.1%) we investigated the relationship of FFM index (FFMI kg*m2), FM index (FMI kg*m2;), and 24-hour e...

  5. Total Energy Intake May Be More Associated with Glycemic Control Compared to Each Proportion of Macronutrients in the Korean Diabetic Population

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    Hye Mi Kang

    2012-08-01

    Full Text Available BackgroundMajor macronutrients for energy intake vary among countries and cultures. Carbohydrates, including rice, are the major component of daily energy intake in Korea. The aim of this study was to examine the association of daily energy intake or each proportion of macronutrients, especially carbohydrates, with glycemic control in diabetic Koreans.MethodsA total of 334 individuals with diabetes (175 men, age 57.4±0.8 years; 159 women, age 60.9±0.9 years who participated in the 2005 Korean National Health and Nutrition Examination Survey were examined. Glycemic control was categorized based on concentration of glycated hemoglobin (HbA1c; HbA1c ≤6.5%; 6.6% to 8.0%; ≥8.1%. Dietary intake was assessed by using a 24-recall item questionnaire.ResultsHigh total energy intake was associated with poor glycemic control (HbA1c ≤6.5%, 1,824±75 kcal; 6.6% to 8.0%, 1,990±57 kcal; ≥8.1%, 2,144±73 kcal; P value for trend=0.002. Each proportion of protein, fat, or carbohydrate was not associated with glycemic control. Even after adjusting for several parameters, the association of daily energy intake with glycemic control still persisted.ConclusionTotal energy intake may be more closely related to glycemic control than each proportionof macronutrients in Korean diabetics.

  6. Associations between Macronutrient Intake and Obstructive Sleep Apnoea as Well as Self-Reported Sleep Symptoms: Results from a Cohort of Community Dwelling Australian Men

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    Yingting Cao

    2016-04-01

    Full Text Available Background: macronutrient intake has been found to affect sleep parameters including obstructive sleep apnoea (OSA in experimental studies, but there is uncertainty at the population level in adults. Methods: cross-sectional analysis was conducted of participants in the Men Androgen Inflammation Lifestyle Environment and Stress cohort (n = 784, age 35–80 years. Dietary intake was measured by a validated food frequency questionnaire. Self-reported poor sleep quality and daytime sleepiness were measured by questionnaires. Overnight in-home polysomnography (PSG was conducted among participants with without previously diagnosed OSA. Results: after adjusting for demographic, lifestyle factors, and chronic diseases, the highest quartile of fat intake was positively associated with excessive daytime sleepiness (relative risk ratio (RRR = 1.78, 95% CI 1.10, 2.89 and apnoea-hypopnoea index (AHI ≥20, (RRR = 2.98, 95% CI 1.20–7.38. Body mass index mediated the association between fat intake and AHI (30%, but not daytime sleepiness. There were no associations between other intake of macronutrient and sleep outcomes. Conclusion: high fat is associated with daytime sleepiness and AHI. Sleep outcomes are generally not assessed in studies investigating the effects of varying macronutrient diets on weight loss. The current result highlights the potential public health significance of doing so.

  7. High-fiber rye diet increases ileal excretion of energy and macronutrients compared with low-fiber wheat diet independent of meal frequency in ileostomy subjects

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    Hanna Isaksson

    2013-12-01

    Full Text Available Background: Whole-grain foods and cereal dietary fiber intake is associated with lower body weight. This may partly result from lower energy utilization of high-fiber diets. Objective: In the present study, the impact on ileal excretion of energy and macronutrients in response to a rye bread high-fiber diet compared to a refined wheat low-fiber diet was investigated. Furthermore, the effect of meal frequency on apparent absorption of nutrients was studied for the first time. Design: Ten participants that had undergone ileostomy consumed standardized iso-caloric diets, including low-fiber wheat bread (20 g dietary fiber per day for 2 weeks followed by high-fiber rye bread (52 g dietary fiber per day for 2 weeks. The diets were consumed in an ordinary (three meals per day and a nibbling (seven meals per day meal frequency in a cross-over design. Ileal effluents were collected during 24 h at the third day of each of the four dietary periods and analyzed for gross energy and nutrient contents. Results: The results showed that intake of rye bread high-fiber diet compared to the refined wheat low-fiber diet caused an increase in ileal excretion of energy and macronutrients. The effect was independent of meal frequency. This suggests that a high intake of rye may result in lower availability of macronutrients for small intestinal digestion and absorption. A regular intake of rye may therefore have implications for weight management.

  8. Macronutrient and fatty acid profiles of meagre (Argyrosomus regius fillets as influenced by harvesting time and boiling

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    Roberta Martelli

    2013-12-01

    Full Text Available The effect of harvesting time and cooking on water, protein, lipid, ash and fatty acid content of farmed meagre was assessed. Significant differences in nutrient content of raw fillets were detected in relation to harvesting time. Cooking by boiling induced loss of some macronutrients, mainly lipids and some fatty acids. Retention of total lipids, C18:2n-6 and C18:3n-3 decreased significantly with harvesting time, while C20:5n-3 (EPA and C22:6n-3 (DHA were retained in the same quantity. DHA retention was higher than that of the other FAs considered, at all harvesting times. The changes detected did not diminish the nutritional value of the fish. Despite losses induced by cooking and the low fat content, typical of this species, 100 g of fillet ensured an intake of EPA plus DHA more than double the recommended daily intake (250 mg day–1, at all harvesting times. The ability to preserve nutrients is an essential requirement for quality maintenance and suggests the possibility of heat-processing fillets. 

  9. Effect of macronutrient enrichment on the size distribution, sorption, and bioconcentration factor of iron by coastal phytoplanktonic diatoms.

    Science.gov (United States)

    Li, Shun-Xing; Zheng, Feng-Ying

    2011-09-01

    The influences of macronutrient enrichment on iron absorption, adsorption, and the bioconcentration factor (BCF) of iron by coastal diatoms were examined. In addition, the distribution of different iron size fractions in seawater in relation to two diatom species exposed to nutrient enrichment over an extended period (6 days for Thalassiosira weissflogii, and 4 days for Skeletonema costatum), was investigated. Iron concentrations were measured of seven size fractions: particles (>0.4 μm), colloidal particles (0.4 μm-100, 100-50, 50-30, 30-10, 10-3 kDa), and soluble species (iron by the diatoms, and the iron species distribution in seawater were affected by the diatom species, as well as the nitrate (N) and phosphate (P) concentration. The addition of P could affect the iron internalization strategy. The content of soluble iron species was positively correlated with the amount of iron absorption by T. weissflogii, but it was not suitable for S. costatum.

  10. Determination of toxic metals, trace and essentials, and macronutrients in Sarpa salpa and Chelon labrosus: risk assessment for the consumers.

    Science.gov (United States)

    Afonso, Aridani; Gutiérrez, Angel J; Lozano, Gonzalo; González-Weller, Dailos; Rubio, Carmen; Caballero, José M; Hardisson, Arturo; Revert, Consuelo

    2017-04-01

    Due to increased environmental pollution, monitoring of contaminants in the environment and marine organisms is a fundamental tool for assessing the existence of risk from their consumption to human health. The levels of toxic heavy metals (Cd, Pb, and Al), trace and essential metals (B, Ba, Co, Cu, Cr, Fe, Li, Mn, Mo, Ni, Sr, V, and Zn), and macronutrients (Ca, K, Mg, Na) in two species of fish for human consumption were quantified in the present study. Eighty samples of muscle tissue and 80 samples of liver tissue belonging to two species of Osteichthyes fish; Sarpa salpa and Chelon labrosus were analyzed. The studied specimens were caught on the northern coast of Gran Canaria (Canary Islands) with fishing rods. As they caught from the shore, they are suitable samples for assessing the toxic levels of representative species caught by local amateur fishermen. The results show that both species are fit for human consumption since they have toxic levels of heavy metals (Cd, Pb, and Al) which are below the maximum established levels; however, the toxic levels of the liver samples are several orders of magnitude higher than the muscle samples, so we discourage their regular consumption. The risk assessment indicated that the two species of fish are safe for the average consumer; however, if the livers of these species are consumed, there could be risks because they exceed the PTWI for Pb and the TWI for Cd.

  11. Comparison of mid-infrared transmission spectroscopy with biochemical methods for the determination of macronutrients in human milk.

    Science.gov (United States)

    Silvestre, Dolores; Fraga, Miriam; Gormaz, María; Torres, Ester; Vento, Máximo

    2014-07-01

    The variability of human milk (HM) composition renders analysis of its components essential for optimal nutrition of preterm fed either with donor's or own mother's milk. To fulfil this requirement, various analytical instruments have been subjected to scientific and clinical evaluation. The objective of this study was to evaluate the suitability of a rapid method for the analysis of macronutrients in HM as compared with the analytical methods applied by cow's milk industry. Mature milk from 39 donors was analysed using an infrared human milk analyser (HMA) and compared with biochemical reference laboratory methods. The statistical analysis was based on the use of paired data tests. The use of an infrared HMA for the analysis of lipids, proteins and lactose in HM proved satisfactory as regards the rapidity, simplicity and the required sample volume. The instrument afforded good linearity and precision in application to all three nutrients. However, accuracy was not acceptable when compared with the reference methods, with overestimation of the lipid content and underestimation of the amount of proteins and lactose contents. The use of mid-infrared HMA might become the standard for rapid analysis of HM once standardisation and rigorous and systematic calibration is provided.

  12. Temporal Trends in Dietary Macronutrient Intakes among Adults in Rural China from 1991 to 2011: Findings from the CHNS

    Directory of Open Access Journals (Sweden)

    Chang Su

    2017-03-01

    Full Text Available Few studies have examined nutrition transitions among the rural population of China, even though half of the Chinese population (about 700 million is living in rural China. To fill this research gap, we examined temporal trends in dietary macronutrient intakes in members of the Chinese rural population aged 18–60 years. The analysis used data from consecutive three-day dietary recalls, collected from the China Health and Nutrition Surveys (CHNS. Mixed-effect models were constructed to obtain adjusted means and to examine temporal trends after adjusting for intra-class correlation within clusters and covariates, including age, sex, geographical region, urbanicity, and income. From 1991 to 2011, a downward trend in daily energy, protein, and carbohydrate intakes was seen in all categories, with a significant reduction among all rural people (p < 0.0001. In contrast, a significant increment in daily fat intake, the proportion of energy from fat, and the proportion of rural people consuming a diet with more than 30% of energy from fat, were observed in the present study (p < 0.0001. These results suggest that adults in rural China have been undergoing a rapid nutrition transition towards a high-fat diet. Therefore, more emphasis should be placed on the quality of fat and maintaining a balanced diet during the process of nutritional education.

  13. Macronutrient intake and risk of urothelial cell carcinoma in the European prospective investigation into cancer and nutrition.

    Science.gov (United States)

    Allen, Naomi E; Appleby, Paul N; Key, Timothy J; Bueno-de-Mesquita, H B; Ros, Martine M; Kiemeney, Lambertus A L M; Tjønneland, Anne; Roswall, Nina; Overvad, Kim; Weikert, Steffen; Boeing, Heiner; Chang-Claude, Jenny; Teucher, Birgit; Panico, Salvatore; Sacerdote, Carlotta; Tumino, Rosario; Palli, Domenico; Sieri, Sabina; Peeters, Petra; Quirós, Jose Ramón; Jakszyn, Paula; Molina-Montes, Esther; Chirlaque, María-Dolores; Ardanaz, Eva; Dorronsoro, Miren; Khaw, Kay-Tee; Wareham, Nick; Ljungberg, Börje; Hallmans, Göran; Ehrnström, Roy; Ericson, Ulrika; Gram, Inger Torhild; Parr, Christine L; Trichopoulou, Antonia; Karapetyan, Tina; Dilis, Vardis; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie-Christine; Fagherrazzi, Guy; Romieu, Isabelle; Gunter, Marc J; Riboli, Elio

    2013-02-01

    Previous studies have suggested that dietary factors may be important in the development of bladder cancer. We examined macronutrient intake in relation to risk of urothelial cell carcinoma among 469,339 men and women in the European Prospective Investigation into Cancer and Nutrition. Associations were examined using Cox regression, stratified by sex, age at recruitment and centre and further adjusted for smoking status and duration, body mass index and total energy intake. After an average of 11.3 years of follow-up, 1,416 new cases of urothelial cell carcinoma were identified. After allowing for measurement error, a 3% increase in the consumption of energy intake from animal protein was associated with a 15% higher risk (95% confidence interval [CI]: 3-30%; p(trend) = 0.01) and a 2% increase in energy from plant protein intake was associated with a 23% lower risk (95% CI: 36-7%, p(trend) = 0.006). Dietary intake of fat, carbohydrate, fibre or calcium was not associated with risk. These findings suggest that animal and/or plant protein may affect the risk of urothelial cell carcinoma, and examination of these associations in other studies is needed.

  14. Predicting Species-Resolved Macronutrient Acquisition during Succession in a Model Phototrophic Biofilm Using an Integrated ‘Omics Approach

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    Stephen R. Lindemann

    2017-06-01

    Full Text Available The principles governing acquisition and interspecies exchange of nutrients in microbial communities and how those exchanges impact community productivity are poorly understood. Here, we examine energy and macronutrient acquisition in unicyanobacterial consortia for which species-resolved genome information exists for all members, allowing us to use multi-omic approaches to predict species’ abilities to acquire resources and examine expression of resource-acquisition genes during succession. Metabolic reconstruction indicated that a majority of heterotrophic community members lacked the genes required to directly acquire the inorganic nutrients provided in culture medium, suggesting high metabolic interdependency. The sole primary producer in consortium UCC-O, cyanobacterium Phormidium sp. OSCR, displayed declining expression of energy harvest, carbon fixation, and nitrate and sulfate reduction proteins but sharply increasing phosphate transporter expression over 28 days. Most heterotrophic members likewise exhibited signs of phosphorus starvation during succession. Though similar in their responses to phosphorus limitation, heterotrophs displayed species-specific expression of nitrogen acquisition genes. These results suggest niche partitioning around nitrogen sources may structure the community when organisms directly compete for limited phosphate. Such niche complementarity around nitrogen sources may increase community diversity and productivity in phosphate-limited phototrophic communities.

  15. Fiber fermentability effects on energy and macronutrient digestibility, fecal traits, postprandial metabolite responses, and colon histology of overweight cats.

    Science.gov (United States)

    Fischer, M M; Kessler, A M; de Sá, L R M; Vasconcellos, R S; Filho, F O Roberti; Nogueira, S P; Oliveira, M C C; Carciofi, A C

    2012-07-01

    Considering the different potential benefits of divergent fiber ingredients, the effect of 3 fiber sources on energy and macronutrient digestibility, fermentation product formation, postprandial metabolite responses, and colon histology of overweight cats (Felis catus) fed kibble diets was compared. Twenty-four healthy adult cats were assigned in a complete randomized block design to 2 groups of 12 animals, and 3 animals from each group were fed 1 of 4 of the following kibble diets: control (CO; 11.5% dietary fiber), beet pulp (BP; 26% dietary fiber), wheat bran (WB; 24% dietary fiber), and sugarcane fiber (SF; 28% dietary fiber). Digestibility was measured by the total collection of feces. After 16 d of diet adaptation and an overnight period without food, blood glucose, cholesterol, and triglyceride postprandial responses were evaluated for 16 h after continued exposure to food. On d 20, colon biopsies of the cats were collected under general anesthesia. Fiber addition reduced food energy and nutrient digestibility. Of all the fiber sources, SF had the least dietary fiber digestibility (P fiber solubility and fermentation rates, fiber sources can induce different physiological responses in cats, reduce energy digestibility, and favor glucose metabolism (SF), or improve gut health (BP).

  16. Interactive Effects of the Feeding of Leucaena Leaves and Curcumin on Macronutrient Digestion and Nitrogen Balance in Beef Cattle

    Directory of Open Access Journals (Sweden)

    C. Yuangklang

    2011-01-01

    Full Text Available Problem statement: The feeding of curcumin to beef cattle has been shown to increase nitrogen retention and decrease the apparent digestibility of acid detergent fiber in beef cattle. It was suggested that there could be interactions between the effects of curcumin and the composition of the ration. Approach: In this study with beef cattle, concentrates without or with curcumin and low or high level of leucaena leaves were fed to assess the possible interactive effects. Apparent macronutrient digestibility and nitrogen balance were measured. Results: When the ration was curcumin free, an increase in the intake of leucaena leaf meal raised the group mean of apparent digestibility of dry matter, organic matter, crude fat, neutral and acid detergent fiber, but the opposite effect was seen for the curcumin-containing rations. Nitrogen retention was raised by extra intake of leucaena leaf meal, but only when the ration did not contain curcumin. The feeding of curcumin intake elevated nitrogen retention, the effect being greater for the ration with low content of leucaena. Conclusion: This study confirms that curcumin feeding has a stimulatory effect on nitrogen retention in beef cattle. The composition of the ration may determine the magnitude of the inhibitory effect of curcumin on the digestibility of acid detergent fiber.

  17. Toxic metal, micro and macronutrient assessment in fish most consumed by Iguape community, Sao Paulo state, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Favaro, Deborah I.T.; Vieira, Andre S.; Bordon, Isabella C.A.C., E-mail: defavaro@ipen.br, E-mail: isabella.bordon@gmail.com [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Farias, Luciana A., E-mail: lufarias2@yahoo.com.br [Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, SP (Brazil); Braga, Elisabete S., E-mail: edsbraga@usp.br [Universidade de Sao Paulo (LABNUT/IO/USP), Sao Paulo, SP (Brazil). Instituto Oceanografico

    2013-07-01

    It is well-known that, fish is an important source of protein for populations around the world. As such, fish consumption has increased because it is a healthy and low cholesterol source of protein and other nutrients. The city of Iguape, in the extreme south of the Sao Paulo State coast, is located in a well-preserved Atlantic Forest region. During the last two centuries the city suffered from drastic environmental changes, reinforcing the importance of environmental monitoring in this region. In the present study, 23 samples of the three most consumed fish species by the Iguape city population were analyzed. Fish samples were bought at local markets, conditioned in isothermic boxes in crushed ice (-4 deg C) and then identified before registering the biometric information (total length, total weight and body weight). The following micro and macronutrients As, Br, Ca, Co, Fe, K, Na, Rb, Sc, Se and Zn concentration in muscle from 02 predatory fish species Macrodon ancylodon (King weakfish - Pescada) and Centropomus parallelus (Fat snook - Robalo peba) and one detritivorus species: Anchoviella lepidentostole (Broadband anchovy - Manjuba) were assessed by INAA. Toxic metals Cd, Hg and Pb were also evaluated by AAS. Statistical correlation between element concentrations and fish species were tested. (author)

  18. Simultaneous determination of macronutrients, micronutrients and trace elements in mineral fertilizers by inductively coupled plasma optical emission spectrometry

    Science.gov (United States)

    de Oliveira Souza, Sidnei; da Costa, Silvânio Silvério Lopes; Santos, Dayane Melo; dos Santos Pinto, Jéssica; Garcia, Carlos Alexandre Borges; Alves, José do Patrocínio Hora; Araujo, Rennan Geovanny Oliveira

    2014-06-01

    An analytical method for simultaneous determination of macronutrients (Ca, Mg, Na and P), micronutrients (Cu, Fe, Mn and Zn) and trace elements (Al, As, Cd, Pb and V) in mineral fertilizers was optimized. Two-level full factorial design was applied to evaluate the optimal proportions of reagents used in the sample digestion on hot plate. A Doehlert design for two variables was used to evaluate the operating conditions of the inductively coupled plasma optical emission spectrometer in order to accomplish the simultaneous determination of the analyte concentrations. The limits of quantification (LOQs) ranged from 2.0 mg kg- 1 for Mn to 77.3 mg kg- 1 for P. The accuracy and precision of the proposed method were evaluated by analysis of standard reference materials (SRMs) of Western phosphate rock (NIST 694), Florida phosphate rock (NIST 120C) and Trace elements in multi-nutrient fertilizer (NIST 695), considered to be adequate for simultaneous determination. Twenty-one samples of mineral fertilizers collected in Sergipe State, Brazil, were analyzed. For all samples, the As, Ca, Cd and Pb concentrations were below the LOQ values of the analytical method. For As, Cd and Pb the obtained LOQ values were below the maximum limit allowed by the Brazilian Ministry of Agriculture, Livestock and Food Supply (Ministério da Agricultura, Pecuária e Abastecimento - MAPA). The optimized method presented good accuracy and was effectively applied to quantitative simultaneous determination of the analytes in mineral fertilizers by inductively coupled plasma optical emission spectrometry (ICP OES).

  19. The role of alternative oxidase in modulating carbon use efficiency and growth during macronutrient stress in tobacco cells.

    Science.gov (United States)

    Sieger, Stephen M; Kristensen, Brian K; Robson, Christine A; Amirsadeghi, Sasan; Eng, Edward W Y; Abdel-Mesih, Amal; Møller, Ian M; Vanlerberghe, Greg C

    2005-06-01

    When wild-type (wt) tobacco (Nicotiana tabacum cv. Petit Havana SR1) cells are grown under macronutrient (P or N) limitation, they induce large amounts of alternative oxidase (AOX), which constitutes a non-energy-conserving branch of the respiratory electron transport chain. To investigate the significance of AOX induction, wt cells were compared with transgenic (AS8) cells lacking AOX. Under nutrient limitation, growth of wt cell cultures was dramatically reduced and carbon use efficiency (g cell dry weight gain g(-1) sugar consumed) decreased by 42-63%. However, the growth of AS8 was only moderately reduced by the nutrient deficiencies and carbon use efficiency values remained the same as under nutrient-sufficient conditions. As a result, the nutrient limitations more severely compromised the tissue nutrient status (P or N) of AS8 than wt cells. Northern analyses and a comparison of the mitochondrial protein profiles of wt and AS8 cells indicated that the lack of AOX in AS8 under P limitation was associated with increased levels of proteins commonly associated with oxidative stress and/or stress injury. Also, the level of electron transport chain components was consistently reduced in AS8 while tricarboxylic acid cycle enzymes did not show a universal trend in abundance in comparison to the wt. Alternatively, the lack of AOX in AS8 cells under N limitation resulted in enhanced carbohydrate accumulation. It is concluded that AOX respiration provides an important general mechanism by which plant cells can modulate their growth in response to nutrient availability and that AOX also has nutrient-specific roles in maintaining cellular redox and carbon balance.

  20. Diet and Macronutrient Optimization in Wild Ursids: A Comparison of Grizzly Bears with Sympatric and Allopatric Black Bears.

    Science.gov (United States)

    Costello, Cecily M; Cain, Steven L; Pils, Shannon; Frattaroli, Leslie; Haroldson, Mark A; van Manen, Frank T

    2016-01-01

    When fed ad libitum, ursids can maximize mass gain by selecting mixed diets wherein protein provides 17 ± 4% of digestible energy, relative to carbohydrates or lipids. In the wild, this ability is likely constrained by seasonal food availability, limits of intake rate as body size increases, and competition. By visiting locations of 37 individuals during 274 bear-days, we documented foods consumed by grizzly (Ursus arctos) and black bears (Ursus americanus) in Grand Teton National Park during 2004-2006. Based on published nutritional data, we estimated foods and macronutrients as percentages of daily energy intake. Using principal components and cluster analyses, we identified 14 daily diet types. Only 4 diets, accounting for 21% of days, provided protein levels within the optimal range. Nine diets (75% of days) led to over-consumption of protein, and 1 diet (3% of days) led to under-consumption. Highest protein levels were associated with animal matter (i.e., insects, vertebrates), which accounted for 46-47% of daily energy for both species. As predicted: 1) daily diets dominated by high-energy vertebrates were positively associated with grizzly bears and mean percent protein intake was positively associated with body mass; 2) diets dominated by low-protein fruits were positively associated with smaller-bodied black bears; and 3) mean protein was highest during spring, when high-energy plant foods were scarce, however it was also higher than optimal during summer and fall. Contrary to our prediction: 4) allopatric black bears did not exhibit food selection for high-energy foods similar to grizzly bears. Although optimal gain of body mass was typically constrained, bears usually opted for the energetically superior trade-off of consuming high-energy, high-protein foods. Given protein digestion efficiency similar to obligate carnivores, this choice likely supported mass gain, consistent with studies showing monthly increases in percent body fat among bears in this

  1. Diet and macronutrient optimization in wild ursids: A comparison of grizzly bears with sympatric and allopatric black bears

    Science.gov (United States)

    Costello, Cecily M; Cain, Steven L; Pils, Shannon R; Frattaroli, Leslie; Haroldson, Mark A.; van Manen, Frank T.

    2016-01-01

    When fed ad libitum, ursids can maximize mass gain by selecting mixed diets wherein protein provides 17 ± 4% of digestible energy, relative to carbohydrates or lipids. In the wild, this ability is likely constrained by seasonal food availability, limits of intake rate as body size increases, and competition. By visiting locations of 37 individuals during 274 bear-days, we documented foods consumed by grizzly (Ursus arctos) and black bears (Ursus americanus) in Grand Teton National Park during 2004–2006. Based on published nutritional data, we estimated foods and macronutrients as percentages of daily energy intake. Using principal components and cluster analyses, we identified 14 daily diet types. Only 4 diets, accounting for 21% of days, provided protein levels within the optimal range. Nine diets (75% of days) led to over-consumption of protein, and 1 diet (3% of days) led to under-consumption. Highest protein levels were associated with animal matter (i.e., insects, vertebrates), which accounted for 46–47% of daily energy for both species. As predicted: 1) daily diets dominated by high-energy vertebrates were positively associated with grizzly bears and mean percent protein intake was positively associated with body mass; 2) diets dominated by low-protein fruits were positively associated with smaller-bodied black bears; and 3) mean protein was highest during spring, when high-energy plant foods were scarce, however it was also higher than optimal during summer and fall. Contrary to our prediction: 4) allopatric black bears did not exhibit food selection for high-energy foods similar to grizzly bears. Although optimal gain of body mass was typically constrained, bears usually opted for the energetically superior trade-off of consuming high-energy, high-protein foods. Given protein digestion efficiency similar to obligate carnivores, this choice likely supported mass gain, consistent with studies showing monthly increases in percent body fat among bears in

  2. Influence of dietary macronutrients on induction of hepatic drug metabolizing enzymes by Coleus forskohlii extract in mice.

    Science.gov (United States)

    Yokotani, Kaori; Chiba, Tsuyoshi; Sato, Yoko; Nakanishi, Tomoko; Murata, Masatsune; Umegaki, Keizo

    2013-01-01

    From studies in mice, we have reported that Coleus forskohlii extract (CFE), a popular herbal weight-loss ingredient, markedly induced hepatic drug metabolizing enzymes, especially cytochrome P450 (CYP), and interacted with co-administered drugs. This study was designed to examine how the induction of drug metabolizing enzymes by CFE was influenced by different levels of macronutrients in the diet. Mice were fed a non-purified diet or semi-purified diet with and without CFE (0.3-0.5%) for 14-18 d, and changes in the ratio of liver weight to body weight, an indicator of hepatic CYP induction, and hepatic drug metabolizing enzymes were analyzed. The ratio of liver weight to body weight, content and activities of CYPs, and activity of glutathione S-transferase were higher in a semi-purified standard diet (AIN93G formula) group than in high sucrose (62.9%) and high fat (29.9%) diet groups. Different levels of protein (7%, 20%, and 33%) in the diets did not influence CFE-induced CYP induction or increase the ratio of liver weight to body weight. The effect of CFE on the ratio of liver weight to body weight was higher with a semi-purified diet than with a non-purified diet, and was similar between dietary administration and intragastric gavage when the CFE dose and the diet were the same. There was a positive correlation between CFE-induced CYP induction and the content of starch in the diets, suggesting that dietary starch potentiates CFE-induced CYP induction in mice. The mechanism of enhanced CYP induction remains unclear.

  3. Analysis of macronutrients intake and body mass index in preschool children in the western region of the Republic of Srpska

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    Đermanović Mirjana

    2015-01-01

    Full Text Available Introduction. Childhood obesity is currently considered to be one of the most prevailing and challenging public health issues in industrialized countries and some developing countries, including the Republic of Srpska. Objective. Our objective was to determine macronutrients intake in collective diet of preschool children and to estimate the rate of obesity in this population. Methods. Samples of food intended for preschool children diet were collected in a preschool facility in the western region of the Republic of Srpska. In daily portions, the content of proteins, fats, carbohydrates, water and mineral matter were determined using standard methods. The body mass index was determined on the basis of anthropometric measurements. Results. An average daily meal contained 17.5 g of fats, 19.1 g of proteins and 101.5 g of carbohydrates. The energy value was 676 Kcal. The analysis of the data from the menu showed that the number of consumed servings of fruits, vegetables, legumes, milk and dairy products was less than one portion per day. However, the amount of consumed meat and meat products exceeded one portion per day. Out of the total number of children, 10.0% were undernourished, 16.7% were overweight and 13.3% were obese. Conclusion. Daily portions in the preschool facility are not in accordance with the recommended dietary allowance for energy and carbohydrates intake, and the composition of meals is inadequate. Parents and caregivers should be encouraged to expose young children to a wide variety of fruit and vegetables, whole grains, low-fat dairy products, and to balance food intake with the requirements.

  4. Contribution of beverages to energy, macronutrient and micronutrient intake of third- and fourth-grade schoolchildren in Quetzaltenango, Guatemala.

    Science.gov (United States)

    Montenegro-Bethancourt, Gabriela; Vossenaar, Marieke; Doak, Colleen M; Solomons, Noel W

    2010-04-01

    Beverages are selected based on availability, culture, taste preference, health, safety and social context. Beverages may be important to energy and to the macronutrient and micronutrient quality of overall intake. The aim of this study was to determine the contribution of beverages to the dietary energy and estimated macro- and micronutrient intake to the diet of young schoolchildren. We analyzed data from third- and fourth-grade urban Guatemalan school-children aged predominantly 8-10 years old. One-day pictorial registries of all beverages, foods and snacks consumed over a 24-h period were collected from children from private (n = 219) and public (n = 230) schools. Food composition nutrient values were assigned to the items consumed. Eleven main categories of beverages were identified. The contribution of each of the 11 beverage categories to energy, macro- and micronutrients was evaluated. The estimated intake of beverages was 475,300 mL, as reported by the 449 children. As a group, the beverage consumed in the greatest quantity was coffee (126,500 mL), followed by plain water (62,000 mL). Beverages represented a mean energy contribution of 418 +/- 26 kcal (21.5% of total dietary energy). The beverages varied in energy density from 0 (water) to 1.5 kcal mL(-1) (thin gruels). Beverages contributed one-third of the dietary carbohydrate. Through the contribution of fortified drinks, beverages were important sources of vitamin A (55%), vitamin C (38%), zinc (21%) and calcium (19%). Milk was an important source for vitamin D (10%). These results show the importance of drinks to nutrition and the balance of concerns of overweight/obesity with micronutrient quality.

  5. Breakfast Macronutrient Composition Influences Thermic Effect of Feeding and Fat Oxidation in Young Women Who Habitually Skip Breakfast

    Science.gov (United States)

    Neumann, Brianna L.; Dunn, Amy; Johnson, Dallas; Adams, J. D.; Baum, Jamie I.

    2016-01-01

    The purpose of this study was to determine if breakfast macronutrient composition improved thermic effect of feeding (TEF) and appetite after a one-week adaptation in young women who habitually skip breakfast. A randomized, controlled study was conducted in females (24.1 ± 2 years), who skip breakfast (≥5 times/week). Participants were placed into one of three groups for eight days (n = 8 per group): breakfast skipping (SKP; no breakfast), carbohydrate (CHO; 351 kcal; 59 g CHO, 10 g PRO, 8 g fat) or protein (PRO; 350 kcal; 39 g CHO, 30 g PRO, 8 g fat). On days 1 (D1) and 8 (D8), TEF, substrate oxidation, appetite and blood glucose were measured. PRO had higher (p < 0.05) TEF compared to SKP and CHO on D1 and D8, with PRO having 29% higher TEF than CHO on D8. On D1, PRO had 30.6% higher fat oxidation than CHO and on D8, PRO had 40.6% higher fat oxidation than CHO. SKP had higher (p < 0.05) fat oxidation on D1 and D8 compared to PRO and CHO. There was an interaction (p < 0.0001) of time and breakfast on appetite response. In addition, CHO had a significant increase (p < 0.05) in PP hunger response on D8 vs. D1. CHO and PRO had similar PP (postprandial) glucose responses on D1 and D8. Consumption of PRO breakfast for 8 days increased TEF compared to CHO and SKP, while consumption of CHO for one week increased PP hunger response. PMID:27517958

  6. Breakfast Macronutrient Composition Influences Thermic Effect of Feeding and Fat Oxidation in Young Women Who Habitually Skip Breakfast

    Directory of Open Access Journals (Sweden)

    Brianna L. Neumann

    2016-08-01

    Full Text Available The purpose of this study was to determine if breakfast macronutrient composition improved thermic effect of feeding (TEF and appetite after a one-week adaptation in young women who habitually skip breakfast. A randomized, controlled study was conducted in females (24.1 ± 2 years, who skip breakfast (≥5 times/week. Participants were placed into one of three groups for eight days (n = 8 per group: breakfast skipping (SKP; no breakfast, carbohydrate (CHO; 351 kcal; 59 g CHO, 10 g PRO, 8 g fat or protein (PRO; 350 kcal; 39 g CHO, 30 g PRO, 8 g fat. On days 1 (D1 and 8 (D8, TEF, substrate oxidation, appetite and blood glucose were measured. PRO had higher (p < 0.05 TEF compared to SKP and CHO on D1 and D8, with PRO having 29% higher TEF than CHO on D8. On D1, PRO had 30.6% higher fat oxidation than CHO and on D8, PRO had 40.6% higher fat oxidation than CHO. SKP had higher (p < 0.05 fat oxidation on D1 and D8 compared to PRO and CHO. There was an interaction (p < 0.0001 of time and breakfast on appetite response. In addition, CHO had a significant increase (p < 0.05 in PP hunger response on D8 vs. D1. CHO and PRO had similar PP (postprandial glucose responses on D1 and D8. Consumption of PRO breakfast for 8 days increased TEF compared to CHO and SKP, while consumption of CHO for one week increased PP hunger response.

  7. Lifespan extension and delay of age-related functional decline caused by Rhodiola rosea depends on dietary macronutrient balance

    Science.gov (United States)

    2013-01-01

    Background This study was conducted to evaluate the effects of rhizome powder from the herb Rhodiola rosea, a traditional Western Ukraine medicinal adaptogen, on lifespan and age-related physiological functions of the fruit fly Drosophila melanogaster. Results Flies fed food supplemented with 5.0 mg/ml and 10.0 mg/ml of R. rosea rhizome powder had a 14% to 17% higher median lifespan, whereas at 30.0 mg/ml lifespan was decreased by 9% to 12%. The preparation did not decrease fly fecundity. The effect of R. rosea supplement on lifespan was dependent on diet composition. Lifespan extension by 15% to 21% was observed only for diets with protein-to-carbohydrate ratios less than 1. Lifespan extension was also dependent on total concentration of macronutrients. Thus, for the diet with 15% yeast and 15% sucrose there was no lifespan extension, while for the diet with protein-to-carbohydrate ratio 20:1 R. rosea decreased lifespan by about 10%. Flies fed Rhodiola preparation were physically more active, less sensitive to the redox-cycling compound menadione and had a longer time of heat coma onset compared with controls. Positive effects of Rhodiola rhizome on stress resistance and locomotor activity were highest at the ‘middle age’. Conclusions The present data show that long-term food supplementation with R. rosea rhizome not only increases D. melanogaster lifespan, but also delays age-related decline of physical activity and increases stress resistance, what depends on protein-to-carbohydrate ratio of the diet. PMID:24472572

  8. Diet and Macronutrient Optimization in Wild Ursids: A Comparison of Grizzly Bears with Sympatric and Allopatric Black Bears.

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    Cecily M Costello

    Full Text Available When fed ad libitum, ursids can maximize mass gain by selecting mixed diets wherein protein provides 17 ± 4% of digestible energy, relative to carbohydrates or lipids. In the wild, this ability is likely constrained by seasonal food availability, limits of intake rate as body size increases, and competition. By visiting locations of 37 individuals during 274 bear-days, we documented foods consumed by grizzly (Ursus arctos and black bears (Ursus americanus in Grand Teton National Park during 2004-2006. Based on published nutritional data, we estimated foods and macronutrients as percentages of daily energy intake. Using principal components and cluster analyses, we identified 14 daily diet types. Only 4 diets, accounting for 21% of days, provided protein levels within the optimal range. Nine diets (75% of days led to over-consumption of protein, and 1 diet (3% of days led to under-consumption. Highest protein levels were associated with animal matter (i.e., insects, vertebrates, which accounted for 46-47% of daily energy for both species. As predicted: 1 daily diets dominated by high-energy vertebrates were positively associated with grizzly bears and mean percent protein intake was positively associated with body mass; 2 diets dominated by low-protein fruits were positively associated with smaller-bodied black bears; and 3 mean protein was highest during spring, when high-energy plant foods were scarce, however it was also higher than optimal during summer and fall. Contrary to our prediction: 4 allopatric black bears did not exhibit food selection for high-energy foods similar to grizzly bears. Although optimal gain of body mass was typically constrained, bears usually opted for the energetically superior trade-off of consuming high-energy, high-protein foods. Given protein digestion efficiency similar to obligate carnivores, this choice likely supported mass gain, consistent with studies showing monthly increases in percent body fat among

  9. Liraglutide suppression of caloric intake competes with the intake-promoting effects of a palatable cafeteria diet, but does not impact food or macronutrient selection.

    Science.gov (United States)

    Hyde, Kellie M; Blonde, Ginger D; le Roux, Carel W; Spector, Alan C

    2017-08-01

    Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) receptor agonist, is used as a treatment for Type 2 diabetes mellitus and obesity because it improves glycemia and decreases food intake. Here, we tested whether chronic activation of the GLP-1 receptor system with liraglutide would induce decreases in intake accompanied by changes in proportional food or macronutrient intake similar to those seen following RYGB in rats when a variety of palatable food options are available. A "cafeteria diet" was used that included: laboratory rodent chow, refried beans (low-fat/low-sugar), low-fat yogurt (low-fat/high-sugar), peanut butter (high-fat/low-sugar) and sugar-fat whip (high-fat/high-sugar). Liraglutide (1mg/kg daily, sc, n=6) induced significant reductions in body weight and total caloric intake compared to saline-injected control rats (n=6). Although access to a cafeteria diet induced increases in caloric intake in both groups relative to chow alone, liraglutide still effectively decreased intake compared with saline-injected rats suggesting that chronic GLP-1 activation competes with the energy density and palatability of available food options in modulating ingestive behavior. Even with the substantial effects on overall intake, liraglutide did not change food choice or relative macronutrient intake when compared to pre-treatment baseline. When drug treatment was discontinued, the liraglutide group increased caloric intake and rapidly gained body weight to match that of the saline group. These results demonstrate that, while liraglutide effectively decreases caloric intake and body weight in rats, it does not cause adjustments in relative macronutrient consumption. Our data also show that drug-induced decreases in intake and body weight are not maintained following termination of treatment. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Macronutrient Intakes in 553 Dutch Elite and Sub-Elite Endurance, Team, and Strength Athletes: Does Intake Differ between Sport Disciplines?

    Science.gov (United States)

    Wardenaar, Floris; Brinkmans, Naomi; Ceelen, Ingrid; Van Rooij, Bo; Mensink, Marco; Witkamp, Renger; De Vries, Jeanne

    2017-01-01

    Web-based 24-h dietary recalls and questionnaires were obtained from 553 Dutch well-trained athletes. The total energy and macronutrient intake was compared between discipline-categories (endurance, team, and strength) within gender, and dietary inadequacy, i.e., too low or high intakes, according to selected recommendations and guidelines, was evaluated by applying a probability approach. On average, 2.83 days per person were reported with a mean energy intake of 2566–2985 kcal and 1997–2457 kcal per day, for men and women, respectively. Between disciplines, small differences in the mean intake of energy and macronutrients were seen for both men and women. Overall, 80% of the athletes met the suggested lower-limit sport nutrition recommendation of 1.2 g·kg−1 of protein per day. The carbohydrate intake of 50%–80% of athletes was between 3 and 5 g·kg−1 bodyweight, irrespective of the category of their discipline. This can be considered as low to moderate, in view of their daily total exercise load (athletes reported on average ~100 min per day). In conclusion, only small differences in the mean energy and macronutrient intake between elite endurance, strength, and team sport athletes, were found. The majority of the athletes were able to meet the generally accepted protein recommendation for athletes, of 1.2 g·kg−1. However, for most athletes, the carbohydrate intake was lower than generally recommended in the existing consensus guidelines on sport nutrition. This suggests that athletes could either optimize their carbohydrate intake, or that average carbohydrate requirements merit a re-evaluation. PMID:28208581

  11. Comparison of macronutrient contents in human milk measured using mid-infrared human milk analyser in a field study vs. chemical reference methods.

    Science.gov (United States)

    Zhu, Mei; Yang, Zhenyu; Ren, Yiping; Duan, Yifan; Gao, Huiyu; Liu, Biao; Ye, Wenhui; Wang, Jie; Yin, Shian

    2017-01-01

    Macronutrient contents in human milk are the common basis for estimating these nutrient requirements for both infants and lactating women. A mid-infrared human milk analyser (HMA, Miris, Sweden) was recently developed for determining macronutrient levels. The purpose of the study is to compare the accuracy and precision of HMA method with fresh milk samples in the field studies with chemical methods with frozen samples in the lab. Full breast milk was collected using electric pumps and fresh milk was analyzed in the field studies using HMA. All human milk samples were thawed and analyzed with chemical reference methods in the lab. The protein, fat and total solid levels were significantly correlated between the two methods and the correlation coefficient was 0.88, 0.93 and 0.78, respectively (p  protein content was significantly lower and the mean fat level was significantly greater when measured using HMA method (1.0 g 100 mL(-1) vs 1.2 g 100 mL(-1) and 3. 7 g 100 mL(-1) vs 3.2 g 100 mL(-1) , respectively, p  protein and fat. There was no significant correlation for lactose between the two methods (p  >  0.05). There was no statistically significant difference in the mean total solid concentration (12.2 g 100 mL(-1) vs 12.3 g 100 mL(-1) , p  >  0.05). Overall, HMA might be used to analyze macronutrients in fresh human milk with acceptable accuracy and precision after recalibrating fat and protein levels of field samples.

  12. Adult Cranberry Beverage Consumers Have Healthier Macronutrient Intakes and Measures of Body Composition Compared to Non-Consumers: National Health and Nutrition Examination Survey (NHANES 2005–2008

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    Kiyah J. Duffey

    2013-12-01

    Full Text Available Flavonoids, present in high levels in cranberries, are potent bioactives known for their health-promoting benefits, but cranberry beverages (CB are not typically recommended as part of a healthy diet. We examine the association between CB consumption with macronutrient intake and weight status. Data for US adults (≥19 years, n = 10,891 were taken from the National Health and Nutrition Examination Survey (NHANES Survey 2005–2008. Total CB consumption was measured over two non-consecutive 24-h dietary recalls. Linear and logistic regression models adjusting for important covariates were used to examine predicted differences between CB consumers and non-consumers on macronutrient and anthropometric outcomes. Results are weighted to be nationally representative. CB consumers (n = 581 were older (>50 year non-Hispanic black females. They consumed an average 221 mL (7.5 oz CB per day. In fully adjusted models CB consumers (vs. non-consumers had higher carbohydrates and total sugars and lower percent energy from protein and total fat (all p < 0.001, but no difference in total energy. A significantly higher proportion of CB consumers were predicted to be normal weight (BMI < 25 kg/m2; p = 0.001 and had to have lower waist circumferences (p = 0.001. Although there was not a significant trend across level of CB intake, low and middle level CB consumers compared to non-consumers were more likely to be normal weight (p < 0.001 and less likely to be overweight/obese (BMI ≥ 25 kg/m2, p < 0.001. Despite having slightly higher daily macronutrient intakes, CB consumers have more desirable anthropometric measures compared to non-consumers.

  13. The postprandial rise in plasma cortisol in men is mediated by macronutrient-specific stimulation of adrenal and extra-adrenal cortisol production.

    Science.gov (United States)

    Stimson, Roland H; Mohd-Shukri, Nor A; Bolton, Jennifer L; Andrew, Ruth; Reynolds, Rebecca M; Walker, Brian R

    2014-01-01

    Circadian variation is a fundamental characteristic of plasma glucocorticoids, with a postprandial rise in cortisol an important feature. The diurnal rhythm is presumed to reflect alterations in hypothalamic-pituitary-adrenal axis activity; however, cortisol is produced not only by the adrenal glands but also by regeneration from cortisone by the enzyme 11β-hydroxysteroid dehydrogenase type 1, mainly in liver and adipose tissue. We tested the contribution of peripheral cortisol regeneration to macronutrient-induced circadian variation of plasma cortisol in humans. This was a randomized, single-blinded, crossover study. The study was conducted at a hospital research facility. Eight normal-weight healthy men participated in the study. Subjects were given isocaloric energy isodense flavor-matched liquid meals composed of carbohydrate, protein, fat, or low-calorie placebo during infusion of the stable isotope tracer 9,11,12,12-[2H]4-cortisol. Plasma cortisol increased similarly after all macronutrient meals (by ∼90 nmol/L) compared with placebo. Carbohydrate stimulated adrenal secretion and extra-adrenal regeneration of cortisol to a similar degree. Protein and fat meals stimulated adrenal cortisol secretion to a greater degree than extra-adrenal cortisol regeneration. The increase in cortisol production by 11β-hydroxysteroid dehydrogenase type 1 was in proportion to the increase in insulin. The postprandial cortisol rise was not accounted for by decreased cortisol clearance. Food-induced circadian variation in plasma cortisol is mediated by adrenal secretion and extra-adrenal regeneration of cortisol. Given that the latter has the more potent effect on tissue cortisol concentrations and that effects on adrenal and extra-adrenal cortisol production are macronutrient specific, this novel mechanism may contribute to the physiological interplay between insulin and glucocorticoids and the contrasting effects of certain diets on postprandial metabolism.

  14. Macronutrient Intakes in 553 Dutch Elite and Sub-Elite Endurance, Team, and Strength Athletes: Does Intake Differ between Sport Disciplines?

    Directory of Open Access Journals (Sweden)

    Floris Wardenaar

    2017-02-01

    Full Text Available Web-based 24-h dietary recalls and questionnaires were obtained from 553 Dutch well-trained athletes. The total energy and macronutrient intake was compared between discipline-categories (endurance, team, and strength within gender, and dietary inadequacy, i.e., too low or high intakes, according to selected recommendations and guidelines, was evaluated by applying a probability approach. On average, 2.83 days per person were reported with a mean energy intake of 2566–2985 kcal and 1997–2457 kcal per day, for men and women, respectively. Between disciplines, small differences in the mean intake of energy and macronutrients were seen for both men and women. Overall, 80% of the athletes met the suggested lower-limit sport nutrition recommendation of 1.2 g·kg−1 of protein per day. The carbohydrate intake of 50%–80% of athletes was between 3 and 5 g·kg−1 bodyweight, irrespective of the category of their discipline. This can be considered as low to moderate, in view of their daily total exercise load (athletes reported on average ~100 minutes per day. In conclusion, only small differences in the mean energy and macronutrient intake between elite endurance, strength, and team sport athletes, were found. The majority of the athletes were able to meet the generally accepted protein recommendation for athletes, of 1.2 g·kg−1. However, for most athletes, the carbohydrate intake was lower than generally recommended in the existing consensus guidelines on sport nutrition. This suggests that athletes could either optimize their carbohydrate intake, or that average carbohydrate requirements merit a re-evaluation.

  15. Macronutrient Intakes in 553 Dutch Elite and Sub-Elite Endurance, Team, and Strength Athletes: Does Intake Differ between Sport Disciplines?

    Science.gov (United States)

    Wardenaar, Floris; Brinkmans, Naomi; Ceelen, Ingrid; Van Rooij, Bo; Mensink, Marco; Witkamp, Renger; De Vries, Jeanne

    2017-02-10

    Web-based 24-h dietary recalls and questionnaires were obtained from 553 Dutch well-trained athletes. The total energy and macronutrient intake was compared between discipline-categories (endurance, team, and strength) within gender, and dietary inadequacy, i.e., too low or high intakes, according to selected recommendations and guidelines, was evaluated by applying a probability approach. On average, 2.83 days per person were reported with a mean energy intake of 2566-2985 kcal and 1997-2457 kcal per day, for men and women, respectively. Between disciplines, small differences in the mean intake of energy and macronutrients were seen for both men and women. Overall, 80% of the athletes met the suggested lower-limit sport nutrition recommendation of 1.2 g·kg(-1) of protein per day. The carbohydrate intake of 50%-80% of athletes was between 3 and 5 g·kg(-1) bodyweight, irrespective of the category of their discipline. This can be considered as low to moderate, in view of their daily total exercise load (athletes reported on average ~100 minutes per day). In conclusion, only small differences in the mean energy and macronutrient intake between elite endurance, strength, and team sport athletes, were found. The majority of the athletes were able to meet the generally accepted protein recommendation for athletes, of 1.2 g·kg(-1). However, for most athletes, the carbohydrate intake was lower than generally recommended in the existing consensus guidelines on sport nutrition. This suggests that athletes could either optimize their carbohydrate intake, or that average carbohydrate requirements merit a re-evaluation.

  16. Macronutrient Intakes in 553 Dutch Elite and Sub-Elite Endurance, Team, and Strength Athletes: Does Intake Differ between Sport Disciplines?

    OpenAIRE

    Floris Wardenaar; Naomi Brinkmans; Ingrid Ceelen; Bo Van Rooij; Marco Mensink; Renger Witkamp; Jeanne De Vries

    2017-01-01

    Web-based 24-h dietary recalls and questionnaires were obtained from 553 Dutch well-trained athletes. The total energy and macronutrient intake was compared between discipline-categories (endurance, team, and strength) within gender, and dietary inadequacy, i.e., too low or high intakes, according to selected recommendations and guidelines, was evaluated by applying a probability approach. On average, 2.83 days per person were reported with a mean energy intake of 2566–2985 kcal and 1997–2457...

  17. Interferência de Euphorbia heterophylla no crescimento e acúmulo de macronutrientes da soja Interference of Euphorbia heterophylla in the growth and macronutrient accumulation of soybean

    Directory of Open Access Journals (Sweden)

    L.B. Carvalho

    2010-01-01

    Full Text Available O grau de interferência depende da densidade de plantas daninhas que infestam a soja. O objetivo deste trabalho foi avaliar características de crescimento e nutrição mineral da soja mantida em convivência com densidades crescentes de Euphorbia heterophylla. O experimento foi conduzido em Jaboticabal, SP, Brasil, entre outubro e dezembro de 2008, em vasos mantidos em campo aberto. Os tratamentos consistiram em submeter uma planta de soja por vaso à convivência com 0, 1, 2, 4, 8 e 16 plantas de E. heterophylla por vaso, da semeadura até o início do florescimento. Nesse período, avaliaram-se, apenas na soja, a altura e o número de trifólios, e em ambas as espécies, a matéria seca e o acúmulo de macronutrientes. Observou-se variação na altura de plantas e redução no número de trifólios e no acúmulo de matéria seca e macronutrientes da soja devido ao maior acúmulo de matéria seca e macronutrientes por densidades crescentes de E. heterophylla. Conclui-se que a soja mantida em convivência com E. heterophylla teve o crescimento e o acúmulo de macronutrientes reduzidos em razão da interferência imposta pela planta daninha.The degree of weed interference depends on the density of the weeds infesting the soybean crop. The objective of this work was to evaluate the growth and mineral nutrition characteristics in soybean maintained in coexistence with increasing densities of Euphorbia heterophylla. The experiment was carried out in Jaboticabal, SP, Brazil, from October through December 2008, in pots maintained under open field conditions. The treatments consisted in submitting one soybean plant per pot to coexistence with 0, 1, 2, 4, 8 and 16 plants of E. heterophylla per pot, from sowing until the beginning of soybean flowering. At this period, only height and number of leaves were evaluated in soybean, while dry matter and macronutrient accumulation were evaluated in both species. Variation in plant height and reduction in the

  18. Obesidade e a substituição de macronutrientes da dieta Obesity and diet macronutrients substitution

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    Eliane Lopes ROSADO

    2001-08-01

    Full Text Available Os fatores envolvidos na gênese da obesidade não são conclusivos, incluindo o papel dos macronutrientes da dieta na suscetibilidade ao ganho de peso. O carboidrato pode ser considerado um componente importante na saciedade. Sua substituição pelo adoçante, reduz o valor energético da dieta, reduzindo a massa corporal. Os efeitos dos adoçantes sobre o apetite dependem da natureza e da densidade dos nutrientes consumidos simultaneamente. Não existem evidencias suficientes que mostrem que os adoçantes causam ganho de peso, mas seu uso pode resultar em compensação energética com alimentos ricos em lipídios. Os lipídios tendem a aumentar a densidade energética da dieta promovendo o superconsumo passivo de energia, além de apresentar baixa prioridade oxidativa, estando associado à baixa saciedade. Sua substituição tem sido relacionada à compensação da ingestão energética, principalmente por carboidratos. Um plano alimentar disciplinado deve incluir alimentos que reduzam a densidade energética da dieta, sem promoção do consumo alimentar.The factors involved in obesity genesis are not conclusive, including the function of diet macronutrients concerning susceptibility of weight gain. Carbohydrate can be considered an important component in satiety. Its substitution for sweeteners decreases the diet caloric value, consequently decreasing body mass. The effects of sweeteners on appetite rely on nature and density of the nutrients that are consumed simultaneously with sweeteners. There are no sufficient evidences showing that sweeteners cause weight gain, but the use of sweeteners may result on energetic compensation with lipid-rich foods. Lipids tend to increase diet energetic density promoting high passive consumption of energy, besides its low oxidative priority, which is associated with low satiety. Lipid substitution has been related to caloric ingestion compensation, mainly for carbohydrates. A disciplined dietetic plan

  19. Simultaneous determination of macronutrients, micronutrients and trace elements in mineral fertilizers by inductively coupled plasma optical emission spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira Souza, Sidnei de [Laboratório de Química Analítica Ambiental (LQA), Departamento de Química, Centro de Ciências Exatas e Tecnologia, Universidade Federal de Sergipe (UFS), 49100-000, São Cristovão, SE (Brazil); Silvério Lopes da Costa, Silvânio [Laboratório de Química Analítica Ambiental (LQA), Departamento de Química, Centro de Ciências Exatas e Tecnologia, Universidade Federal de Sergipe (UFS), 49100-000, São Cristovão, SE (Brazil); Coordenação de Química, Universidade Federal de Alagoas (UFAL), Campus Arapiraca, 57309-005, Arapiraca, AL (Brazil); Santos, Dayane Melo; Santos Pinto, Jéssica dos; Garcia, Carlos Alexandre Borges [Laboratório de Química Analítica Ambiental (LQA), Departamento de Química, Centro de Ciências Exatas e Tecnologia, Universidade Federal de Sergipe (UFS), 49100-000, São Cristovão, SE (Brazil); and others

    2014-06-01

    An analytical method for simultaneous determination of macronutrients (Ca, Mg, Na and P), micronutrients (Cu, Fe, Mn and Zn) and trace elements (Al, As, Cd, Pb and V) in mineral fertilizers was optimized. Two-level full factorial design was applied to evaluate the optimal proportions of reagents used in the sample digestion on hot plate. A Doehlert design for two variables was used to evaluate the operating conditions of the inductively coupled plasma optical emission spectrometer in order to accomplish the simultaneous determination of the analyte concentrations. The limits of quantification (LOQs) ranged from 2.0 mg kg{sup −1} for Mn to 77.3 mg kg{sup −1} for P. The accuracy and precision of the proposed method were evaluated by analysis of standard reference materials (SRMs) of Western phosphate rock (NIST 694), Florida phosphate rock (NIST 120C) and Trace elements in multi-nutrient fertilizer (NIST 695), considered to be adequate for simultaneous determination. Twenty-one samples of mineral fertilizers collected in Sergipe State, Brazil, were analyzed. For all samples, the As, Ca, Cd and Pb concentrations were below the LOQ values of the analytical method. For As, Cd and Pb the obtained LOQ values were below the maximum limit allowed by the Brazilian Ministry of Agriculture, Livestock and Food Supply (Ministério da Agricultura, Pecuária e Abastecimento — MAPA). The optimized method presented good accuracy and was effectively applied to quantitative simultaneous determination of the analytes in mineral fertilizers by inductively coupled plasma optical emission spectrometry (ICP OES). - Highlights: • Determination of inorganic constituents in mineral fertilizers was proposed. • Experimental design methodology was used to optimize analytical method. • The sample preparation procedure using diluted reagents (HNO{sub 3} and H{sub 2}O{sub 2}) was employed. • The analytical method was satisfactorily to the determination of thirteen elements. • The

  20. A Randomized Controlled Trial of Two Different Macronutrient Profiles on Weight, Body Composition and Metabolic Parameters in Obese Adolescents Seeking Weight Loss.

    Science.gov (United States)

    Truby, Helen; Baxter, Kimberley; Ware, Robert S; Jensen, Diane E; Cardinal, John W; Warren, Janet M; Daniels, Lynne; Davies, Peter S W; Barrett, Paula; Blumfield, Michelle L; Batch, Jennifer A

    2016-01-01

    Adolescent obesity is difficult to treat and the optimal dietary pattern, particularly in relation to macronutrient composition, remains controversial. This study tested the effect of two structured diets with differing macronutrient composition versus control, on weight, body composition and metabolic parameters in obese adolescents. A randomized controlled trial conducted in a children's hospital. Eighty seven obese youth (means: age 13.6 years, BMI z-score 2.2, waist: height ratio 0.65, 69% female) completed a psychological preparedness program and were then randomized to a short term 'structured modified carbohydrate' (SMC, 35% carbohydrate; 30% protein; 35% fat, n = 37) or a 'structured low fat' (SLF, 55% carbohydrate; 20% protein; 25% fat, n = 36) or a wait listed control group (n = 14). Anthropometric, body composition and biochemical parameters were measured at randomization and after 12 weeks, and analyzed under the intention to treat principle using analysis of variance models. After 12 weeks, data was collected from 79 (91%) participants. BMI z-scores were significantly lower in both intervention groups compared to control after adjusting for baseline values, SLF vs. control, mean difference = -0.13 (95%CI = -0.18, -0.07), Pchanges in weight, body composition and metabolic improvements compared to control. The use of a structured eating system which allows flexibility but limited choices can assist in weight change and the rigid application of a low fat eating pattern is not exclusive in its efficacy. International Clinical Trials Registry ISRCTN49438757.

  1. The effect of socioeconomic indicators and macronutrient intake rate on body composition in adolescents 12 to 16 years old in Merida, Yucatan.

    Science.gov (United States)

    Datta Banik, Sudip; Andrade Olalde, Ana Carolina; Rodriguez, Luis; Dickinson, Federico

    2014-01-01

    Intake pattern of macronutrients (protein, lipid, carbohydrate) and socioeconomic status (SES) are major causes of high child and adolescent overweight and obesity prevalences in Mexico. An evaluation was done of the relationship between body mass index (BMI)-based nutritional status and body composition (BC), macronutrient intake rates (MIR) and SES indicators in 127 boys and 156 girls aged 12 to 16 years attending schools in Merida, Mexico. Anthropometric variables included height, weight, and BMI. The BC (body fat mass, fat-free mass, dry lean mass) was estimated by bioelectrical impedance (Bodystat 1500 MDD). The MIR were estimated following FAO/WHO/UNO standard (1985). Proxy socioeconomic indicators included parents' age (as a maturity indicator) and education, fathers' occupation, school type and monthly household food expenditure per capita. Excess weight (overweight + obesity) assessed by BMI, was higher in boys (40.16 %) than in girls (33.97 %). Boys had higher BMI, less fat mass and higher fat-free mass than girls. The MIR did not vary significantly in response to age, sex, BC or SES. Participants with higher SES were taller and heavier, had higher fat-free mass and lower fat mass. In the studied adolescents, anthropometric and BC values, and overweight and obesity rates were more associated with SES than MIR.

  2. LITTER AND MACRONUTRIENT DEPOSITION IN A STAND OF BLACK WATTLE (Acacia mearnsii De Wild. IN THE STATE OF RIO GRANDE DO SUL, BRAZIL

    Directory of Open Access Journals (Sweden)

    Márcio Viera

    2010-08-01

    Full Text Available This study evaluated litter and macronutrient deposition in a six year-old black wattle (Acacia mearnsii De Wild. stand, in Butia-RS. Five plots (18mx24m of litter were systematically allocated, each one with four trap collectors of 1 m2. The litter intercepted was collected monthly between January 2002 and December 2003. After collection, litter was divided into leaves, flowers, fruits and caterpillar (Adeloneivaia subangulata feces, oven dried, weighed, milled and analyzed for N, P, K, Ca and Mg contents. The average annual litter deposition reached 4.32 Mg ha-1, and was composed of 75.5, 11.1, 11.2 and 2.2% of leaves, flowers, fruits and feces, respectively. Litter deposition was more concentrated in the spring. The higher deposition of nutrients was through the leaf fraction, which contributed annually with a great amount of litter biomass, although not showing the highest nutrient concentrations. The supply of total amount of macronutrients to the soil was of 74.8 of N, 26.8 of K, 23.1 of Ca, 7.9 of Mg and 2.4 of P (kg ha-1.

  3. Impact of the Bolsa Família Program on energy, macronutrient, and micronutrient intakes: Study of the Northeast and Southeast

    Directory of Open Access Journals (Sweden)

    Naiara SPERANDIO

    Full Text Available ABSTRACT Objective: To assess the impact of the Bolsa Família Program on the energy and nutrient intakes of beneficiaries from the Brazilian Northeast and Southeast regions. Methods: The study used data from the 2008-2009 Pesquisa de Orçamento Famíliar, which assessed individual food intake on two nonconsecutive days of individuals aged more than 10 years. Based the personal information booklet, food intake values were transformed into nutritional values (energy and nutrients. Analysis of the impact measure was preceded by propensity score matching, a technique that matches some socioeconomic characteristics of beneficiaries and nonbeneficiaries. Once the score was calculated, the impact of the Bolsa Família Program was estimated by nearest neighbor matching. Results: The program increased energy and macronutrient intakes and decreased calcium and vitamin A, D, E, and C intakes of adolescent beneficiaries in both regions. Adult beneficiaries from the Southeast region increased their fiber, iron, and selenium intakes, and those from the Northeast region decreased their energy, lipid, added sugar, sodium, zinc, vitamin E, and pyridoxine intakes. Conclusion: The results show a positive impact of the program on the energy and macronutrient intakes, and a negative impact on the intakes of most study micronutrients, especially in adolescents, which reinforce the importance of implementing intersectoral actions to improve the nutritional quality of the Bolsa Família Program beneficiaries' diet.

  4. Effect of mixed-cropping and water-stress on macro-nutrients and biochemical constituents of rhizomatous medicinal plants in Central Himalaya, India

    Institute of Scientific and Technical Information of China (English)

    L.S.Kandari; K.S.Rao; R.K.Maikhuri; Kusum Payal

    2012-01-01

    Plants in the alpine zone mainly depend on the reserved food materials stored in their rhizomes for the next growing season.We investigated the effect of mixed cropping (Phaseolus vulgaris L.var.Pinto)with four rhizomatous medicinal plants,i.e.,Angelica glauca,Arnebia benthamii,Rheum emodi and Pleurospermum angelicoides as well as three levels of water stress treatment under two conditions (shade net and open field) on macronutrients (NPK) and biochemicals (carbohydrates and protein).The experiment was conducted by completely randomized design (CDR).The data were analyzed with ANOVA as well as CDR.The experimental results show that in all the species shade conditions with sever water stress (SSWS) increased the level of macronutrients (NPK).However,(N) concentration was highest under shade with mixed cropping (SMIX).Under SMIX,carbohydrate content was highest than open field control conditions (CONT).This investigation results demonstrate that mixed cropping of medicinal plants with Phaseolus vulgaris could be a good livelihood option in the mountainous regions of Indian Central Himalaya.And the water-stress conditions along with mixed cropping could improve the biochemical constituents in the rhizome of these species.

  5. Deficiência nutricional em mudas de umbuzeiro decorrente da omissão de macronutrientes Nutritional deficiency in "umbuzeiro" seedlings caused by the omission of macronutrients

    Directory of Open Access Journals (Sweden)

    Francisco César Gonçalves

    2006-06-01

    Full Text Available O objetivo deste trabalho foi avaliar o crescimento e os sintomas visuais de deficiência de macronutrientes em mudas de umbuzeiro, Spondias tuberosa, cultivadas em solução nutritiva completa e com omissão individual de N, P, K, Ca, Mg e S. As ausências de Ca, N, Mg e K provocaram redução do crescimento das mudas. A omissão de macronutrientes provocou alterações morfológicas características da deficiência nutricional. Observa-se maior exigência em N, K, Ca e Mg na fase inicial de crescimento e a redução na massa de matéria seca total segue a ordem: Ca > N > K > Mg > S > P.The objective of this work was to evaluate the growth and the visual symptoms of macronutrients deficiency in "umbuzeiro" seedlings (Spondias tuberosa cultivated on complete nutritive solution and on solution with individual omission of N, P, K, Ca, Mg and S. The absences of Ca, N, Mg and K caused a reduction in seedling growth. The omission of individual macronutrients conducted to morphological disorders related to the nutritional deficiency. A higher requirement of N, K, Ca and Mg is observed during the initial phase of the growth, and the reduction in total dry matter follows the order: Ca > N > K > Mg > S > P.

  6. An analysis of partial efficiencies of energy utilisation of different macronutrients by barramundi (Lates calcarifer) shows that starch restricts protein utilisation in carnivorous fish.

    Science.gov (United States)

    Glencross, Brett D; Blyth, David; Bourne, Nicholas; Cheers, Susan; Irvin, Simon; Wade, Nicholas M

    2017-02-01

    This study examined the effect of including different dietary proportions of starch, protein and lipid, in diets balanced for digestible energy, on the utilisation efficiencies of dietary energy by barramundi (Lates calcarifer). Each diet was fed at one of three ration levels (satiety, 80 % of initial satiety and 60 % of initial satiety) for a 42-d period. Fish performance measures (weight gain, feed intake and feed conversion ratio) were all affected by dietary energy source. The efficiency of energy utilisation was significantly reduced in fish fed the starch diet relative to the other diets, but there were no significant effects between the other macronutrients. This reduction in efficiency of utilisation was derived from a multifactorial change in both protein and lipid utilisation. The rate of protein utilisation deteriorated as the amount of starch included in the diet increased. Lipid utilisation was most dramatically affected by inclusion levels of lipid in the diet, with diets low in lipid producing component lipid utilisation rates well above 1·3, which indicates substantial lipid synthesis from other energy sources. However, the energetic cost of lipid gain was as low as 0·65 kJ per kJ of lipid deposited, indicating that barramundi very efficiently store energy in the form of lipid, particularly from dietary starch energy. This study defines how the utilisation efficiency of dietary digestible energy by barramundi is influenced by the macronutrient source providing that energy, and that the inclusion of starch causes problems with protein utilisation in this species.

  7. Adult cranberry beverage consumers have healthier macronutrient intakes and measures of body composition compared to non-consumers: National Health and Nutrition Examination Survey (NHANES) 2005-2008.

    Science.gov (United States)

    Duffey, Kiyah J; Sutherland, Lisa A

    2013-12-01

    Flavonoids, present in high levels in cranberries, are potent bioactives known for their health-promoting benefits, but cranberry beverages (CB) are not typically recommended as part of a healthy diet. We examine the association between CB consumption with macronutrient intake and weight status. Data for US adults (≥19 years, n = 10,891) were taken from the National Health and Nutrition Examination Survey (NHANES) Survey 2005-2008. Total CB consumption was measured over two non-consecutive 24-h dietary recalls. Linear and logistic regression models adjusting for important covariates were used to examine predicted differences between CB consumers and non-consumers on macronutrient and anthropometric outcomes. Results are weighted to be nationally representative. CB consumers (n = 581) were older (>50 year) non-Hispanic black females. They consumed an average 221 mL (7.5 oz) CB per day. In fully adjusted models CB consumers (vs. non-consumers) had higher carbohydrates and total sugars and lower percent energy from protein and total fat (all p consumers were predicted to be normal weight (BMI consumers compared to non-consumers were more likely to be normal weight (p consumers have more desirable anthropometric measures compared to non-consumers.

  8. Flaxseed energy and macronutrients balance Influencia de la energía de la linaza en el equilibrio de macronutrientes

    Directory of Open Access Journals (Sweden)

    C. Gonçalves de Oliveira

    2012-10-01

    Full Text Available Background/objectives: Flaxseed has functional properties in the reduction of the risk of chronic non-communicable diseases such as cardiovascular disease, diabetes and cancer. Regardless of its high energy density, the consumption of flaxseed tends to promote body weight maintenance. The purpose of this study was to evaluate energy and macronutrient balance after flaxseed consumption. Subjects/methods: Twenty four healthy volunteers were allocated into 3 experimental groups, when they consumed flaxseed (FS, defatted flaxseed flour (FF, or flaxseed oil (FO. During the control period they were provided a diet without flaxseed products for 7-9 days. Following that diets containing 70 g of one of the flaxseed products were consumed for another 7-9 day- period. Test foods were consumed exclusively in the laboratory and fecal excretion was collected during the study. There was a higher energy excretion (P Introducción/objetivos: La linaza tiene propiedades funcionales en la reducción del riesgo de enfermedades crónicas no transmisibles tales como las enfermedades cardiovasculares, diabetes y cáncer. A pesar de su alta densidad de energía, el consumo de linaza tiende a favorecer el mantenimiento del peso corporal. El propósito de este estudio fue evaluar la energía y el equilibrio de macronutrientes después del consumo de linaza. Materiales y métodos: Veinticuatro voluntarios sanos fueron distribuidos en 3 grupos experimentales, cuando consumieron linaza (LI, harina de linaza desgrasada (LD, o aceite de linaza (AL. Durante el período de control se les proporcionó una dieta de 7-9 días sin productos de linaza. Enseguida, durante otro período de 7-9 días, fueron consumidas dietas que contenían 70g de uno de los productos de linaza. Los alimentos de prueba fueron consumidos exclusivamente en el laboratorio y la excreción fecal se recogió durante el estudio. Hubo una excreción de energía más alta (P < 0,05 en los grupos LD y LI, en

  9. Ingesta de macronutrientes en adolescentes escolarizados en Soria capital Macronutrients intake in school teenagers in Soria capital

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    I. Carrero

    2005-06-01

    Full Text Available Objetivos: Estudiar la ingesta de macronutrientes en adolescentes sorianos de 10-19 años, así como su índice de masa corporal (IMC. Metodología: Encuesta sobre el consumo de alimentos durante siete días en una muestra accidental de adolescentes (54 varones y 56 mujeres de escuelas públicas de Soria capital. Valoración del aporte medio diario de energía, glúcidos, lípidos y proteínas mediante el programa "Alimentación y Salud" que también da valores de ingesta diaria recomendada (IDR para cada individuo en función de sus características particulares. Utilización del test de la t de Student para comparar los valores medios de la ingesta estimada para los distintos nutrientes y sus ingestas diarias recomendadas. Resultados: En general, el aporte de energía, proteínas y lípidos supera de forma estadísticamente significativa las ingestas diarias recomendadas, mientras que el de glúcidos es inferior a las recomendaciones. En cuanto al tipo de lípidos ingerido, la ingesta es superior a la recomendada para colesterol, ácidos grasos monoinsaturados y ácidos grasos saturados, pero no para los ácidos grasos poliinsaturados. En chicas, a partir de los 13 años, más del 12% tiene un valor de índice de masa corporal superior a 26 kg/m², sin embargo, entre los 10-12 años el 20% de la población estudiada tiene este parámetro por debajo de 16 kg/m². Conclusiones: En función de los resultados obtenidos, parece conveniente realizar algún tipo de intervención nutricional entre los adolescentes de la capital soriana para promover una alimentación saludable que permita prevenir posibles trastornos (obesidad, anorexia, etc..Objectives: To study the macronutrients intake in Soria teenagers from 10 to 19 years, as well as their body mass index (BMI. Methods: A seven-day diet questionnaire filled in by an accidental sample of teenagers (54 boys and 56 girls from public schools in the capital. Working out the average daily intake of

  10. Changes in weight loss, body composition and cardiovascular disease risk after altering macronutrient distributions during a regular exercise program in obese women

    Science.gov (United States)

    2010-01-01

    Background This study's purpose investigated the impact of different macronutrient distributions and varying caloric intakes along with regular exercise for metabolic and physiological changes related to weight loss. Methods One hundred forty-one sedentary, obese women (38.7 ± 8.0 yrs, 163.3 ± 6.9 cm, 93.2 ± 16.5 kg, 35.0 ± 6.2 kg•m-2, 44.8 ± 4.2% fat) were randomized to either no diet + no exercise control group (CON) a no diet + exercise control (ND), or one of four diet + exercise groups (high-energy diet [HED], very low carbohydrate, high protein diet [VLCHP], low carbohydrate, moderate protein diet [LCMP] and high carbohydrate, low protein [HCLP]) in addition to beginning a 3x•week-1 supervised resistance training program. After 0, 1, 10 and 14 weeks, all participants completed testing sessions which included anthropometric, body composition, energy expenditure, fasting blood samples, aerobic and muscular fitness assessments. Data were analyzed using repeated measures ANOVA with an alpha of 0.05 with LSD post-hoc analysis when appropriate. Results All dieting groups exhibited adequate compliance to their prescribed diet regimen as energy and macronutrient amounts and distributions were close to prescribed amounts. Those groups that followed a diet and exercise program reported significantly greater anthropometric (waist circumference and body mass) and body composition via DXA (fat mass and % fat) changes. Caloric restriction initially reduced energy expenditure, but successfully returned to baseline values after 10 weeks of dieting and exercising. Significant fitness improvements (aerobic capacity and maximal strength) occurred in all exercising groups. No significant changes occurred in lipid panel constituents, but serum insulin and HOMA-IR values decreased in the VLCHP group. Significant reductions in serum leptin occurred in all caloric restriction + exercise groups after 14 weeks, which were unchanged in other non-diet/non-exercise groups

  11. Changes in weight loss, body composition and cardiovascular disease risk after altering macronutrient distributions during a regular exercise program in obese women

    Directory of Open Access Journals (Sweden)

    Roberts Mike D

    2010-11-01

    Full Text Available Abstract Background This study's purpose investigated the impact of different macronutrient distributions and varying caloric intakes along with regular exercise for metabolic and physiological changes related to weight loss. Methods One hundred forty-one sedentary, obese women (38.7 ± 8.0 yrs, 163.3 ± 6.9 cm, 93.2 ± 16.5 kg, 35.0 ± 6.2 kg•m-2, 44.8 ± 4.2% fat were randomized to either no diet + no exercise control group (CON a no diet + exercise control (ND, or one of four diet + exercise groups (high-energy diet [HED], very low carbohydrate, high protein diet [VLCHP], low carbohydrate, moderate protein diet [LCMP] and high carbohydrate, low protein [HCLP] in addition to beginning a 3x•week-1 supervised resistance training program. After 0, 1, 10 and 14 weeks, all participants completed testing sessions which included anthropometric, body composition, energy expenditure, fasting blood samples, aerobic and muscular fitness assessments. Data were analyzed using repeated measures ANOVA with an alpha of 0.05 with LSD post-hoc analysis when appropriate. Results All dieting groups exhibited adequate compliance to their prescribed diet regimen as energy and macronutrient amounts and distributions were close to prescribed amounts. Those groups that followed a diet and exercise program reported significantly greater anthropometric (waist circumference and body mass and body composition via DXA (fat mass and % fat changes. Caloric restriction initially reduced energy expenditure, but successfully returned to baseline values after 10 weeks of dieting and exercising. Significant fitness improvements (aerobic capacity and maximal strength occurred in all exercising groups. No significant changes occurred in lipid panel constituents, but serum insulin and HOMA-IR values decreased in the VLCHP group. Significant reductions in serum leptin occurred in all caloric restriction + exercise groups after 14 weeks, which were unchanged in other non

  12. Changes in weight loss, body composition and cardiovascular disease risk after altering macronutrient distributions during a regular exercise program in obese women.

    Science.gov (United States)

    Kerksick, Chad M; Wismann-Bunn, Jennifer; Fogt, Donovan; Thomas, Ashli R; Taylor, Lem; Campbell, Bill I; Wilborn, Colin D; Harvey, Travis; Roberts, Mike D; La Bounty, Paul; Galbreath, Melyn; Marcello, Brandon; Rasmussen, Christopher J; Kreider, Richard B

    2010-11-22

    This study's purpose investigated the impact of different macronutrient distributions and varying caloric intakes along with regular exercise for metabolic and physiological changes related to weight loss. One hundred forty-one sedentary, obese women (38.7 ± 8.0 yrs, 163.3 ± 6.9 cm, 93.2 ± 16.5 kg, 35.0 ± 6.2 kg•m(-2), 44.8 ± 4.2% fat) were randomized to either no diet + no exercise control group (CON) a no diet + exercise control (ND), or one of four diet + exercise groups (high-energy diet [HED], very low carbohydrate, high protein diet [VLCHP], low carbohydrate, moderate protein diet [LCMP] and high carbohydrate, low protein [HCLP]) in addition to beginning a 3x•week(-1) supervised resistance training program. After 0, 1, 10 and 14 weeks, all participants completed testing sessions which included anthropometric, body composition, energy expenditure, fasting blood samples, aerobic and muscular fitness assessments. Data were analyzed using repeated measures ANOVA with an alpha of 0.05 with LSD post-hoc analysis when appropriate. All dieting groups exhibited adequate compliance to their prescribed diet regimen as energy and macronutrient amounts and distributions were close to prescribed amounts. Those groups that followed a diet and exercise program reported significantly greater anthropometric (waist circumference and body mass) and body composition via DXA (fat mass and % fat) changes. Caloric restriction initially reduced energy expenditure, but successfully returned to baseline values after 10 weeks of dieting and exercising. Significant fitness improvements (aerobic capacity and maximal strength) occurred in all exercising groups. No significant changes occurred in lipid panel constituents, but serum insulin and HOMA-IR values decreased in the VLCHP group. Significant reductions in serum leptin occurred in all caloric restriction + exercise groups after 14 weeks, which were unchanged in other non-diet/non-exercise groups. Overall and over the entire

  13. Uso da fertirrigação e teores de macronutrientes em planta de pimentão Fertigation application and macronutrients concentrations in plant of bell pepper

    Directory of Open Access Journals (Sweden)

    Francisco F. N. Marcussi

    2005-12-01

    Full Text Available Este estudo teve o objetivo de determinar os teores de macronutrientes (N, P, K, Ca, Mg e S nos diferentes órgãos do híbrido de pimentão Elisa, sob fertirrigação e ambiente protegido, por meio de coletas de plantas durante o ciclo. Ao final do experimento, obtiveram-se os teores dos macronutrientes no fruto, folha, caule, raiz e na planta como um todo, em cada etapa de crescimento. A fertilização no ciclo estudado, 140 dias, foi feita via irrigação localizada (gotejamento. O experimento foi desenvolvido nas dependências do Departamento de Recursos Naturais - Ciência do Solo, FCA-UNESP, Câmpus de Botucatu - SP, e constou de oito tratamentos (épocas de coleta de planta: 0; 20; 40; 60; 80; 100; 120 e 140 dias após o transplante das mudas e quatro repetições, sendo cada repetição formada por quatro plantas. Os resultados mostram que os teores de macronutrientes encontrados na planta de pimentão seguem, na média, a seguinte ordem decrescente: K (39,9 g kg-1 > N (28,3 g kg-1 > Ca (12,8 g kg-1 > Mg (5,9 g kg-1 > S (4,1 g kg-1 > P (3,7 g kg-1.In this study, it was aimed the determination of macronutrients contents (N, P, K, Ca, Mg and S in different organs of the hybrid of bell pepper Elisa, under fertigation and protected atmosphere, through eight times of plant extraction. At the end of the experiment it was obtained the contents of macronutrients in the fruit, leaf, stem and root and in the plant as a whole, in each growth stage. The fertilization in the studied cycle, 140 days, was done through localized fertigation (drip system. The experiment was developed in the Department of Natural Resources - Soil Science, FCA-UNESP, Botucatu - SP, Brazil. The experiment consisted of eight treatments (time of plant extraction: 0; 20; 40; 60; 80; 100; 120, and 140 days after the transplant of the seedlings and four repetitions, being each repetition formed by four plants. The macronutrients contents found in the plant have the following

  14. Unhealthy eating habits, physical exercise and macronutrient intakes are predictors of anthropometric indicators in the Women's Health Trial: Feasibility Study in Minority Populations.

    Science.gov (United States)

    Bhargava, Alok; Guthrie, Joanne F

    2002-12-01

    The increasing prevalence of obesity in the USA, especially among minority populations, is a serious public health concern. This present study analysed repeated measurements at baseline and at 6 and 12 months on 351 women in the control group and 575 women in the intervention group of the Women's Health Trial: Feasibility Study in Minority Populations. Dynamic random effects models were estimated using the three repeated observations to explain the effects of energy and macronutrient intakes, physical exercise, unhealthy eating habits and socio-economic characteristics on the subjects' body weights and waist and hip circumferences. In both the control and intervention groups, physical exercise was negatively associated with body weight and with waist and hip circumferences, while an index of unhealthy eating habits was positively associated (Peating habits and increasing physical exercise can reduce obesity prevalence in the USA.

  15. Characterization of the effects of macronutrient deficiencies in mangabeira seedlings Caracterização dos efeitos de deficiências de macronutrientes em mudas de mangabeira

    Directory of Open Access Journals (Sweden)

    Layara Alexandre Bessa

    2012-12-01

    Full Text Available Knowledge of the mineral nutrition requirements of mangabeira (Hancornia speciosa Gomes is relatively scarce and rudimentary because there is a lack of consistent data concerning its nutritional demands at different developmental stages. The aim of this research was to characterize the visual symptoms of macronutrient deficiencies and to evaluate the effects of these deficiencies on the growth, the production of dry matter, and the leaf content of mangabeira. To achieve this goal, a greenhouse experiment was conducted at the Goiano Federal Institute (Instituto Federal Goiano in Rio Verde - GO, from January to June 2011 in which mangabeira plants were arranged in a random block design and grown in nutrient solutions. This experiment was replicated four times. The plants were treated with either a complete nutrient solution or a nutrient solution from which the individual macronutrient of interest (nitrogen (N, phosphorous (P, potassium (K, magnesium (Mg, calcium (Ca, or sulfur (S had been omitted. The omission of a macronutrient from the nutrient solution resulted in morphological alterations that were characteristic symptoms of the particular nutritional deficiency and caused decreases in growth and dry matter mass production. The accumulation of macronutrients displayed the following order in mangabeira leaves: N>K>Ca>P>S>Mg.Os conhecimentos de nutrição mineral da mangabeira (Hancornia speciosa Gomes são relativamente escassos e incipientes, faltando dados consistentes sobre sua demanda nutricional desde a fase de viveiro até a fase de produção. Com o objetivo de caracterizar os sintomas visuais de carências de macronutrientes, avaliar os efeitos da deficiência no crescimento, produção de massa da matéria seca e conteúdo foliar de mangabeira, foi conduzido um experimento em casa de vegetação no IF Goiano em Rio Verde - GO, nos períodos de janeiro a junho de 2011, onde plantas de mangaba foram cultivadas em solução nutritiva, no

  16. Assessment of habitual energy and macronutrient intake in adults: comparison of a seven day food record with a dietary history interview

    DEFF Research Database (Denmark)

    Høidrup, S.; Andreasen, A. H.; Osler, M.

    2002-01-01

    Objective: To examine the quantitative agreement between a 7 day food record and a diet history interview when these are conducted under the same conditions and to evaluate whether the two methods assess habitual diet intake differently among subgroups of age and body mass index (BMI). Design......: Cross-sectional study. Setting: Population study, Denmark. Subjects: A total of 175 men and 173 women aged 30-60 y, selected randomly from a larger population sample of Danish adults. Interventions: All subjects had habitual diet intake assessed by a diet history interview and completed a 7 day food...... record within 3 weeks following the interview. The diet history interview and coding of records were performed by the same trained dietician. Main outcome measure: Median between-method difference in assessment of total energy intake, absolute intake of macronutrients, and nutrient energy percentages...

  17. Effect of dietary macronutrient proportion on intermediate metabolism and oxidative status in sturgeon (Acipenser naccarii) and trout (Oncorhynchus mykiss): comparative study.

    Science.gov (United States)

    Furné, M; García-Gallego, M; Hidalgo, M C; Sanz, A

    2016-08-01

    Three isoenergetic diets varying the proportion of dietary energy supplied by each of the macronutrients (carbohydrate, lipid, or protein) were delivered, to farmed sturgeon (Acipenser naccarii) and trout (Oncorhynchus mykiss), to test the possible effects on the intermediate metabolism and oxidative status in liver, white muscle, and heart. In trout, there is an adaptive metabolic response to an increase in lipids and carbohydrates in the diet. However, this does not happen in the sturgeon. These differences may be due to different dietary habits of both species. In terms of oxidative status, only the liver displayed oxidative stress in both species, showing an increase in the lipid peroxidation and antioxidant enzyme activities after feeding with the high-lipid and high-protein diet.

  18. [Effect of educational nutrition program on the energy and macronutrients intake of preschoolers attending Junji day care centres in the eastern sector of Santiago, Chile].

    Science.gov (United States)

    Vásquez, Fabián; Andrade, Margarita; Rodríguez, M del Pilar; Salazar, Gabriela

    2008-09-01

    The objective of this study was to evaluate the change on the energy and macronutrients intake in obese and eutrophic preschoolers, attending National Board of Day Care Centres (JUNJI), in the eastern area of Santiago, as product of an educational intervention in intake, nutrition and physical activity, sustained in the theory of the social cognitive learning and the model of community organization. The sample comprised of thirty five obese children, plus eighty five eutrophic children (4-5 years olds). Energy intake was evaluated, measuring full two days a week plus one weekend day. At the day care centre, all ingested food was weighed, and when back at home, child food-intake was recalled. During the stay at the day care centres, the intervention produced a reduction in: energy, proteins, lipids and carbohydrates in obese girls (pobese boys (pobese girls and eutrophic boys (pobese boys, reduced the intake of calories (pobese girls the reduction was in calories (pobesity and chronic diseases.

  19. Chloride regulates leaf cell size and water relations in tobacco plants.

    Science.gov (United States)

    Franco-Navarro, Juan D; Brumós, Javier; Rosales, Miguel A; Cubero-Font, Paloma; Talón, Manuel; Colmenero-Flores, José M

    2016-02-01

    Chloride (Cl(-)) is a micronutrient that accumulates to macronutrient levels since it is normally available in nature and actively taken up by higher plants. Besides a role as an unspecific cell osmoticum, no clear biological roles have been explicitly associated with Cl(-) when accumulated to macronutrient concentrations. To address this question, the glycophyte tobacco (Nicotiana tabacum L. var. Habana) has been treated with a basal nutrient solution supplemented with one of three salt combinations containing the same cationic balance: Cl(-)-based (CL), nitrate-based (N), and sulphate+phosphate-based (SP) treatments. Under non-saline conditions (up to 5 mM Cl(-)) and no water limitation, Cl(-) specifically stimulated higher leaf cell size and led to a moderate increase of plant fresh and dry biomass mainly due to higher shoot expansion. When applied in the 1-5 mM range, Cl(-) played specific roles in regulating leaf osmotic potential and turgor, allowing plants to improve leaf water balance parameters. In addition, Cl(-) also altered water relations at the whole-plant level through reduction of plant transpiration. This was a consequence of a lower stomatal conductance, which resulted in lower water loss and greater photosynthetic and integrated water-use efficiency. In contrast to Cl(-), these effects were not observed for essential anionic macronutrients such as nitrate, sulphate, and phosphate. We propose that the abundant uptake and accumulation of Cl(-) responds to adaptive functions improving water homeostasis in higher plants.

  20. A Randomized Controlled Trial of Two Different Macronutrient Profiles on Weight, Body Composition and Metabolic Parameters in Obese Adolescents Seeking Weight Loss.

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    Helen Truby

    Full Text Available Adolescent obesity is difficult to treat and the optimal dietary pattern, particularly in relation to macronutrient composition, remains controversial. This study tested the effect of two structured diets with differing macronutrient composition versus control, on weight, body composition and metabolic parameters in obese adolescents.A randomized controlled trial conducted in a children's hospital.Eighty seven obese youth (means: age 13.6 years, BMI z-score 2.2, waist: height ratio 0.65, 69% female completed a psychological preparedness program and were then randomized to a short term 'structured modified carbohydrate' (SMC, 35% carbohydrate; 30% protein; 35% fat, n = 37 or a 'structured low fat' (SLF, 55% carbohydrate; 20% protein; 25% fat, n = 36 or a wait listed control group (n = 14. Anthropometric, body composition and biochemical parameters were measured at randomization and after 12 weeks, and analyzed under the intention to treat principle using analysis of variance models.After 12 weeks, data was collected from 79 (91% participants. BMI z-scores were significantly lower in both intervention groups compared to control after adjusting for baseline values, SLF vs. control, mean difference = -0.13 (95%CI = -0.18, -0.07, P<0.001; SMC vs. control, -0.14 (-0.19, -0.09, P<0.001, but there was no difference between the two intervention diet groups: SLF vs. SMC, 0.00 (-0.05, 0.04, P = 0.83.Both dietary patterns resulted in similar changes in weight, body composition and metabolic improvements compared to control. The use of a structured eating system which allows flexibility but limited choices can assist in weight change and the rigid application of a low fat eating pattern is not exclusive in its efficacy.International Clinical Trials Registry ISRCTN49438757.

  1. Patterns of milk macronutrients and bioactive molecules across lactation in a western lowland gorilla (Gorilla gorilla) and a Sumatran orangutan (Pongo abelii).

    Science.gov (United States)

    Power, Michael L; Schulkin, Jay; Drought, Heather; Milligan, Lauren A; Murtough, Katie L; Bernstein, Robin M

    2017-03-01

    In addition to nutrients, milk contains signaling molecules that influence offspring development. Human milk is similar in nutrient composition to that of apes, but appears to differ in other aspects such as immune function. We examine the longitudinal patterns across lactation of macronutrients, the metabolic hormone adiponectin, the growth factors epidermal growth factor (EGF) and transforming growth factor β2 (TGF-β2), and two receptors for these growth factors (EGF-R and TGF-β2-RIII) in milk samples collected between days 175 and 313 postpartum from a Sumatran orangutan (Pongo abelii) and between days 3 and 1,276 from a western lowland gorilla (Gorilla gorilla), and compare the results with human data from the literature. Milk macronutrients and hormones were measured using standard nutritional assays and commercially available enzyme immunoassay kits. Ape milk fat content was lower than human milk values, but protein and sugar were similar. Concentrations of all bioactive molecules were consistently detectable except for TGF-β2 in orangutan milk. Concentrations of adiponectin, EGF, and TGF-β2 in both ape milks were lower than found in human breast milk. Concentrations declined with infant age in orangutan milk; in gorilla milk concentrations were high in the first months, and then declined to stable levels until 2-3 years after birth when they increased. However, when expressed on a per energy basis milk constituent values did not differ with age for orangutan and the variation was reduced at all ages in gorilla. In orangutan milk, the ratio of EGF-R to EGF was constant, with EGF-R at 7.7% of EGF; in gorilla milk the EGF-R concentration was 4.4 ± 0.2% of the EGF concentration through 3 years and then increased. These data indicate that potent signaling molecules such as EGF and adiponectin are present in ape milk at physiological concentrations. However, human breast milk on average contains higher concentrations.

  2. Marcha de absorção de macronutrientes na cultura do girassol Macronutrient uptake of sunflower (Helianthus annuus L.

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    Luiz Henrique Saes Zobiole

    2010-04-01

    Full Text Available Este trabalho teve como objetivo estabelecer curvas de acúmulo de macronutrientes na cultura do girassol. Para isso, foi instalado um experimento em campo sobre Latossolo Vermelho distroférrico de textura muito argilosa, localizado na fazenda experimental da Embrapa Soja, em Londrina/PR. As parcelas foram constituídas de 14 linhas com 25 m de comprimento cada e espaçamento entrelinhas de 0,70 m, resultando em área total de 245 m². Cada parcela foi repetida quatro vezes. A adubação de semeadura foi de 300 kg ha-1 da fórmula 5-20-20, aplicada a lanço, antes do plantio. A adubação de cobertura foi parcelada em duas aplicações: 25 e 1 kg ha-1 de N e B, respectivamente, sendo a primeira aos 21 e a segunda aos 35 dias após a semeadura. O híbrido utilizado foi o BRS-191, e a densidade final de plantas foi de 40.000 plantas ha-1. Amostras de plantas foram coletadas em intervalos de 14 dias após a emergência e separadas em pecíolos, folhas, caules e, quando existentes, em capítulo e em aquênios. Após secagem, cada parte da planta foi pesada e moída para, em seguida, determinarem-se os teores de N, P, K, Ca, Mg e S. A partir desses nutrientes e da matéria seca de cada parte da planta, foram obtidas as curvas de acúmulo. Verificou-se que, para obtenção de produtividades superiores a 3.000 kg ha-1, o híbrido BRS 191 extrai aproximadamente 150, 24, 286, 116, 42 e 24 kg ha-1 de N, P, K, Ca, Mg e S, respectivamente, resultando na seguinte ordem de extração: K > N > Ca > Mg > P = S. Em relação à exportação, a ordem dos nutrientes foi a seguinte: N > P = K > Mg = S > Ca. Portanto, atenção especial deve ser dada à manutenção da adequada disponibilidade de N, K e Ca, devido à alta demanda da cultura por esses nutrientes.This study aimed to establish curves of macronutrient accumulation in sunflower. The experiment was conducted in the field on a Typic Hapludox, at the experimental station of Embrapa Soja in Londrina, State

  3. Deficiências de macronutrientes no estado nutricional da mamoneira cultivar Iris Deficiencies of macronutrients on nutritional status of castor bean cultivar Iris

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    José Lavres Junior

    2005-02-01

    Full Text Available Os objetivos deste trabalho foram avaliar o efeito da deficiência dos macronutrientes no crescimento e estado nutricional da mamoneira (Ricinus communis L. e a obtenção do quadro sintomatológico das deficiências de N, P, K, Ca, Mg e S. Cultivou-se Ricinus communis L. cultivar Iris em solução nutritiva, tendo como tratamentos soluções completa e deficientes em N, P, K, Ca, Mg e S. Foram determinadas a concentração indireta de clorofila, a atividade da redutase do nitrato, os teores solúveis de N (NO3-, P (H2PO4- e K+ e realizados testes rápidos para N, P e K. As deficiências de N, Ca, S e Mg foram as que mais restringiram a produção de massa de matéria seca, na ordem decrescente: N>Ca>S>Mg>K>P. Os maiores acúmulos de macronutrientes, no tratamento completo, foram observados nas raízes e no limbo das folhas inferiores. As concentrações críticas para N e Ca, ambas no limbo das folhas superiores e, Mg, no pecíolo das inferiores foram, respectivamente, 46,7, 13,8 e 6,5 g kg-1. As deficiências influenciaram as leituras do clorofilômetro. A atividade da redutase do nitrato guardou relação direta com a determinação da clorofila. Os teores de N (NO3-, P (H2PO4- e K+ foram menores nas folhas deficientes em N, P e K, respectivamente, o mesmo acontecendo quando avaliadas pela análise de toque.The objectives of this work were to evaluate the effect of macronutrient deficiencies on growth and on nutritional status of castor beans (Ricinus communis L., and to obtain the symptoms of the lack of N, P, K, Ca, Mg and S. Nutrient solutions containing all macronutrients and those from which one of these elements was omitted were the treatments used. The following determinations were made: chlorophyll (indirectly, nitrate reductase activity, NO3--N, H2PO4--P and K+, both on soluble fractions, and by spot tests. Deficiencies of N, Ca, S and Mg were the most limiting for dry matter production, followed in decreasing order by those of K and

  4. Acúmulo de macronutrientes pela cultivar de cebola "Superex" estabelecida por semeadura direta Evaluating macronutrients accumulated in onion plants of the 'Superex' cultivar in direct seeding system

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    Diego Resende de Queirós Pôrto

    2007-08-01

    Full Text Available O objetivo do trabalho foi quantificar o acúmulo de macronutrientes ao longo do ciclo da cebola, cv. "Superex", estabelecida por semeadura direta. O experimento foi conduzido na Fazenda Rio Doce, entre os municípios de Itobi e São José do Rio Pardo, SP. As amostragens de plantas foram realizadas aos 30, 50, 70, 90, 110, 130 e 150 dias após a semeadura (DAS, para determinação da matéria seca e do acúmulo dos nutrientes (N, P, K, Ca, Mg e S. Os acúmulos máximos de matéria seca da parte aérea e do bulbo foram, respectivamente, de 4,70g planta-1 e 17,86g planta-1, aos 150 DAS. A parte aérea e o bulbo contribuíram, respectivamente, com cerca de 20 e 80% na matéria seca da planta inteira ao final do ciclo. A seqüência de acúmulo dos nutrientes verificada para a cebola "Superex" foi: K>N>Ca>S>Mg>P. A planta de cebola acumulou 202,43; 31,23; 295,28; 172,42; 35,20 e 73,47mg, respectivamente, de N, P, K, Ca, Mg e S. Exportou, pelo bulbo, 67% do N, 85% do P, 68% do K, 57% do Ca, 56% do Mg e 81% do S acumulado pela planta.This research was aimed at counting the concentration of macronutrients throughout the onion, cv Superex, established by direct seeding. The experiment was conducted at Rio Doce farm, between the counties of Itobi and São José do Rio Pardo, state of São Paulo, Brazil (21°37'16"S and 46°53'15"W. The macronutrients N, P, K, Ca, Mg, and S as well as plant dry matter content were evaluated in plant samples taken at 30, 50, 70, 90, 110, and 150 days after seeding (DAS. The maximum dry matter content in the bulb and in the aerial part were reached at 150 DAS and were, respectively, of 4.70 and 17.86g plant-1. The aerial part and the bulb contributed respectively with 20 and 80% of the whole mature plant dry matter. The macronutrients were accumulated in the plant in the following order: K>N>Ca>S>Mg>P. The onion plant accumulated 202.43; 31.23; 295.28; 172.42; 35.20 e 73.47 mg of N, P, K, Ca, Mg, and S, respectively, and

  5. Effects of prey macronutrient content on body composition and nutrient intake in a web-building spider.

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    Jesse Hawley

    Full Text Available The nutritional composition of diets can vary widely in nature and have large effects on the growth, reproduction and survival of animals. Many animals, especially herbivores, will tightly regulate the nutritional composition of their body, which has been referred to as nutritional homeostasis. We tested how experimental manipulation of the lipid and protein content of live prey affected the nutrient reserves and subsequent diet regulation of web-building spiders, Argiope keyserlingi. Live locusts were injected with experimental solutions containing specific amounts of lipid and protein and then fed to spiders. The nutrient composition of the spiders' bodies was directly related to the nutrient composition of the prey on which they fed. We then conducted an experiment where spiders were fed either high lipid or high protein prey and subsequently provided with two large unmanipulated locusts. Prior diet did not affect the amount or ratio of lipid and protein ingested by spiders when feeding on unmanipulated prey. Argiope keyserlingi were flexible in the storage of lipid and protein in their bodies and did not bias their extraction of nutrients from prey to compensate for previously biased diets. Some carnivores, especially those that experience frequent food limitation, may be less likely to strictly regulate their body composition than herbivores because food limitation may encourage opportunistic ingestion and assimilation of nutrients.

  6. Effects of prey macronutrient content on body composition and nutrient intake in a web-building spider.

    Science.gov (United States)

    Hawley, Jesse; Simpson, Stephen J; Wilder, Shawn M

    2014-01-01

    The nutritional composition of diets can vary widely in nature and have large effects on the growth, reproduction and survival of animals. Many animals, especially herbivores, will tightly regulate the nutritional composition of their body, which has been referred to as nutritional homeostasis. We tested how experimental manipulation of the lipid and protein content of live prey affected the nutrient reserves and subsequent diet regulation of web-building spiders, Argiope keyserlingi. Live locusts were injected with experimental solutions containing specific amounts of lipid and protein and then fed to spiders. The nutrient composition of the spiders' bodies was directly related to the nutrient composition of the prey on which they fed. We then conducted an experiment where spiders were fed either high lipid or high protein prey and subsequently provided with two large unmanipulated locusts. Prior diet did not affect the amount or ratio of lipid and protein ingested by spiders when feeding on unmanipulated prey. Argiope keyserlingi were flexible in the storage of lipid and protein in their bodies and did not bias their extraction of nutrients from prey to compensate for previously biased diets. Some carnivores, especially those that experience frequent food limitation, may be less likely to strictly regulate their body composition than herbivores because food limitation may encourage opportunistic ingestion and assimilation of nutrients.

  7. Linking phytoplankton nitrogen uptake, macronutrients and chlorophyll- a in SW Atlantic waters: The case of the Gulf of San Jorge, Argentina

    Science.gov (United States)

    Paparazzo, Flavio E.; Williams, Gabriela N.; Pisoni, Juan P.; Solís, Miriam; Esteves, José L.; Varela, Diana E.

    2017-08-01

    We compared biological and chemical parameters in surface waters of the Gulf of San Jorge to better understand carbon export and the factors that control phytoplankton production in an area of the Argentinian Continental Shelf, a vastly under sampled region of the SW Atlantic Ocean. In April of 2012, we estimated new and regenerated primary production in the Gulf by measuring nitrate and ammonium uptake, respectively. We also measured macronutrient, and in situ chlorophyll-a concentrations, which were compared to chlorophyll-a estimates from remote sensing. Although the Gulf of San Jorge presents high levels of chlorophyll-a and primary production, the relationship between these parameters is not straightforward. Previous studies showed that surface chlorophyll-a explains only part of the variance in euphotic-zone integrated primary production, and that satellite-derived chlorophyll-a underestimates in situ primary production. Our results showed large spatial variability in the Gulf, with transitional physico-chemical conditions, such as fronts, that could favor an increase in biological production. In situ chlorophyll-a concentrations were highest at the mid-shelf station (6.0 mg m- 3) and lowest at the northernmost location by an order of magnitude. Remote sensing measurements of chlorophyll-a underestimated our in situ chlorophyll-a concentrations. Total nitrogen (nitrate + ammonium) uptake showed relatively similar rates throughout the study area (≈ 130 nM-N d- 1), except in the northernmost station where it was much lower (53 nM-N d- 1). This north region had a distinct water mass and maximal levels of macronutrients (nitrate ≈ 6 μM, ammonium ≈ 1.2 μM, phosphate ≈ 1.2 μM and silicic acid ≈ 4 μM). For the entire sampling region, chlorophyll-a concentrations strongly correlated with total nitrogen uptake (r = 0.76, n = 8, p < 0.05) and new primary production (r = 0.78, n = 8, p < 0.05). Values of the f-ratio were 0.9 in mid-shelf, and ranged

  8. Commercially available avian and mammalian whole prey diet items targeted for consumption by managed exotic and domestic pet felines: macronutrient, mineral, and long-chain fatty acid composition.

    Science.gov (United States)

    Kerr, Katherine R; Kappen, Kelly L; Garner, Lindsay M; Swanson, Kelly S

    2014-01-01

    Whole prey diets encourage species-typical behaviors making them popular in the zoo and home setting for captive exotic and domestic felids, respectively. We evaluated macronutrient, mineral, and long-chain fatty acid composition of 20 whole prey items: mice (1-2, 10-13, 21-25, 30-40, and 150-180 days of age); rats (1-4, 10-13, 21-25, 33-42, and >60 days of age); rabbits (still born, 30-45 days, >65 days with skin, and >65 days of age with skin removed); chicken (1-3 days of age, ground adult); duck (ground adult); and quail (1-3, 21-40, and >60 days of age). Composition of whole prey was highly variable (15-40% DM, 34-75% CP, 10-60% fat, and 8-18% ash). A majority of whole prey samples (15/20) had at least one mineral or fatty acid below AAFCO [] or NRC [] minimum recommended concentrations for domestic cats (K, Na, Cl, Mg, Cu, Mn, and/or Zn; total fat, linolenic acid, arachidonic acid and/or EPA and DHA). These data identify potential nutrient deficiencies allowing for alterations in dietary formulation prior to long-term feeding.

  9. Randomization to plant-based dietary approaches leads to larger short-term improvements in Dietary Inflammatory Index scores and macronutrient intake compared with diets that contain meat.

    Science.gov (United States)

    Turner-McGrievy, Gabrielle M; Wirth, Michael D; Shivappa, Nitin; Wingard, Ellen E; Fayad, Raja; Wilcox, Sara; Frongillo, Edward A; Hébert, James R

    2015-02-01

    Studies have examined nutrient differences among people following different plant-based diets. However, all of these studies have been observational. The aim of the present study was to examine differences in nutrient intake and Dietary Inflammatory Index (DII) scores among overweight and obese (body mass index 25.0-49.9 kg/m(2)) adults randomized to receive dietary instruction on a vegan (n = 12), vegetarian (n = 13), pescovegetarian (n = 13), semivegetarian (n = 13), or omnivorous (n = 12) diet during a 6-month randomized controlled trial. Nutrient intake, nutrient adequacy, and DII score were assessed via two 24-hour dietary recalls (Automated Self-Administered 24-Hour Dietary Recall) at baseline and at 2 and 6 months. Differences in nutrient intake and the DII were examined using general linear models with follow-up tests at each time point. We hypothesized that individuals randomized to the vegan diet would have lower DII scores and greater improvements in fiber, carbohydrate, fat, saturated fat, and cholesterol at both 2 and 6 months as compared with the other 4 diets. Participants randomized to the vegan diet had significantly greater changes in most macronutrients at both time points, including fat and saturated fat, as well as cholesterol and, at 2 months, fiber, as compared with most of the other diet groups (Ps plant-based dietary approaches, such as vegan and vegetarian diets, should be given consideration. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. EFFECT OF SUBSTRATES CONTAINING COMPOSTS WITH THE PARTICIPATION OF MUNICIPAL SEWAGE SLUDGE ON FLOWERING AND MACRONUTRIENT CONTENT IN THE LEAVES OF GARDEN PANSY (Viola × wittrockiana Gams.

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    Agnieszka Zawadzińska

    2014-04-01

    Full Text Available The aim of the study was to assess the impact of substrates containing composts made ​​from municipal sewage sludge and straw or sawdust on flowering, leaf greenness index and macronutrient content in the leaves of ‘Fancy Carmine with Blotch’ garden pansy. Two composts, with the following compositions: K I – 70% municipal sewage sludge, 30% rye straw; K II – 70% municipal sewage sludge, 30% coniferous tree sawdust, were used for the preparation of substrates. Six substrates of peat and compost at 25, 50 and 75% (by volume were prepared. The control object was a peat substrate, pH 5.8–6.0, supplemented with Azofoska at 2.5 g·dm-3. It has been found that leaf greenness index of pansy increased with an increasing share of compost. Composts involving municipal sewage sludge at the level of 50% had a more positive influence on the abundance of pansy flowering than at 25 and 75%. The content of total nitrogen, phosphorus, potassium and sulfur in the leaves increased with increasing the dose of compost. The content of total phosphorus in the leaves at the end of pansy cultivation in compost substrates ranged optimally for this species. In the experiment conducted in 2006, pansies contained more total nitrogen, potassium and sulfur than the flowering pansies planted in 2005.

  11. The role of macronutrient intake in reducing the risk of obesity and overweight among carriers of different polymorphisms of FTO gene. A review

    Science.gov (United States)

    Przeliorz-Pyszczek, Anna; Regulska-Ilow, Bożena

    Obesity is a growing problem worldwide. The risk of the excessive body weight occurrence is a multifactorial issue. Environmental factors, lifestyle habits, diet, physical activity level, as well as genetic predisposition can increase obesity risk. One of the genes studied – the FTO gene - plays a crucial role in obesity occurrence. Individuals who carry risk alleles of specific single nucleotide polymorphisms (SNP) have a greater risk of being overweight. Recent studies revealed that specific macronutrient diet composition can influence differently on the FTO expression. The aim of this article is to review the recent literature on the topic of the FTO gene, its influence on overweight and obesity prevalence and the role of diet in modifying its impact on the risk of the excessive body weight occurrence. There are not many studies focusing on the dietary intervention influence on the FTO gene expression. As far as it has been researched it seems that the proper dietary habits can modify the FTO gene risk allele influence on obesity susceptibility.

  12. A pilot study to determine whether using a lightweight, wearable micro-camera improves dietary assessment accuracy and offers information on macronutrients and eating rate.

    Science.gov (United States)

    Pettitt, Claire; Liu, Jindong; Kwasnicki, Richard M; Yang, Guang-Zhong; Preston, Thomas; Frost, Gary

    2016-01-14

    A major limitation in nutritional science is the lack of understanding of the nutritional intake of free-living people. There is an inverse relationship between accuracy of reporting of energy intake by all current nutritional methodologies and body weight. In this pilot study we aim to explore whether using a novel lightweight, wearable micro-camera improves the accuracy of dietary intake assessment. Doubly labelled water (DLW) was used to estimate energy expenditure and intake over a 14-d period, over which time participants (n 6) completed a food diary and wore a micro-camera on 2 of the days. Comparisons were made between the estimated energy intake from the reported food diary alone and together with the images from the micro-camera recordings. There was an average daily deficit of 3912 kJ using food diaries to estimate energy intake compared with estimated energy expenditure from DLW (P=0·0118), representing an under-reporting rate of 34 %. Analysis of food diaries alone showed a significant deficit in estimated daily energy intake compared with estimated intake from food diary analysis with images from the micro-camera recordings (405 kJ). Use of the micro-camera images in conjunction with food diaries improves the accuracy of dietary assessment and provides valuable information on macronutrient intake and eating rate. There is a need to develop this recording technique to remove user and assessor bias.

  13. Control of voluntary feed intake in fish: a role for dietary oxygen demand in Nile tilapia (Oreochromis niloticus) fed diets with different macronutrient profiles.

    Science.gov (United States)

    Saravanan, S; Geurden, I; Figueiredo-Silva, A C; Kaushik, S J; Haidar, M N; Verreth, J A J; Schrama, J W

    2012-10-28

    It has been hypothesised that, at non-limiting water oxygen conditions, voluntary feed intake (FI) in fish is limited by the maximal physiological capacity of oxygen use (i.e. an 'oxystatic control of FI in fish'). This implies that fish will adjust FI when fed diets differing in oxygen demand, resulting in identical oxygen consumption. Therefore, FI, digestible energy (DE) intake, energy balance and oxygen consumption were monitored at non-limiting water oxygen conditions in Nile tilapia fed diets with contrasting macronutrient composition. Diets were formulated in a 2 × 2 factorial design in order to create contrasts in oxygen demand: two ratios of digestible protein (DP):DE ('high' v. 'low'); and a contrast in the type of non-protein energy source ('starch' v. 'fat'). Triplicate groups of tilapia were fed each diet twice daily to satiation for 48 d. FI (g DM/kg(0·8) per d) was significantly lower (9·5%) in tilapia fed the starch diets relative to the fat diets. The DP:DE ratio affected DE intakes (P demand of these diets. Indeed, DE intakes of fish showed an inverse linear relationship with dietary oxygen demand (DOD; R 2 0·81, P theory), oxygen consumption of fish was identical among three out of the four diets. Altogether, these results demonstrate the involvement of metabolic oxygen use and DOD in the control of FI in tilapia.

  14. SUMO: regulating the regulator

    Directory of Open Access Journals (Sweden)

    Bossis Guillaume

    2006-06-01

    Full Text Available Abstract Post-translational modifiers of the SUMO (Small Ubiquitin-related Modifier family have emerged as key regulators of protein function and fate. While the past few years have seen an enormous increase in knowledge on SUMO enzymes, substrates, and consequences of modification, regulation of SUMO conjugation is far from being understood. This brief review will provide an overview on recent advances concerning (i the interplay between sumoylation and other post-translational modifications at the level of individual targets and (ii global regulation of SUMO conjugation and deconjugation.

  15. Acúmulo e exportação de macronutrientes em melancia sem sementes Accumulation and exportation of macronutrients in seedless watermelon

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    Leilson C. Grangeiro

    2005-07-01

    Full Text Available Com o objetivo de determinar o acúmulo e a exportação de macronutrientes em melancia sem sementes, híbrido Nova, conduziu-se um experimento em Itápolis (SP, de outubro a dezembro de 2001, em um ARGISSOLO VERMELHO-AMARELO Distrófico. As amostragens de plantas foram realizadas aos 15; 30; 45; 60 e 70 dias após transplantio (DAT, sendo quantificados o acúmulo de massa seca e de macronutrientes na folha, caule + ramos e frutos. O acúmulo de peso seco foi lento até 30 DAT, intensificando-se a partir deste, alcançando no final do ciclo o total de 545,1 g planta-1, onde as folhas participaram com 30%, caule + ramos com 31% e os frutos com 39%. Até 30 DAT, o acúmulo de nutrientes também foi pequeno, sendo que com a frutificação, houve um forte incremento na quantidade de nutrientes acumulados, com maior demanda no período de 45 a 60 DAT. A ordem decrescente dos macronutrientes acumulados pela cultura foi: K>N>Ca>P>Mg>S. Os frutos exportaram 20,3 kg ha-1 de N; 4,0 kg ha-1 de P; 26,6 kg ha-1 de K; 1,4 kg ha-1 de Ca; 1,6 kg ha-1 de Mg e 1,4 kg ha-1 de S.The accumulation and exportation of nutrients of the seedless watermelon hybrid Nova was determined under field conditions. The experiment was carried out in Typic Paleudult soil, in the Itápolis region, São Paulo State, Brazil. Sampling of the plants was done at 15; 30; 45; 60 and 70 days after transplanting date (DAT and the accumulation of dry mass and macronutrients was quantified in leaves, stem + branches and fruits. The dry mass accumulation was slow until 30 DAT, intensifying with the beginning of the fruit development. At the end of the cycle, the average contribution of leaves, stems + branches and fruits, was respectively of 30; 31 and 39%. The accumulation of nutrients followed the curve of dry mass accumulation. The larger demand for macronutrients occurred from 45 to 60 DAT. The order of nutrients accumulation for the culture was: K>N>Ca>P>Mg>S. The fruits exported 20.3 kg

  16. The Multi-Scale Response of Water Quality, Biodiversity and Carbon Sequestration to Coupled Macronutrient Cycling from Source to Sea: TURF2SURF

    Science.gov (United States)

    Wade, Andrew; Emmett, Bridget; Jago, Colin; Stutter, Marc; Biggs, Jeremy

    2016-04-01

    Turf2Surf is a large, multi-disciplinary project that aims to test the hypothesis that the spatial and temporal patterns of water quality, C sequestration and biodiversity are better explained through the large-scale coupling of C, N and P cycles than by single cycle, single system approaches. To achieve this, a catchment-scale study of the River Conwy (349 km2) in Wales is being done with emphasis on determining when, where and how coupled macronutrient (C, N, P) cycling occurs in the biogeochemical hot-spots of the soils, the riparian zone, instream and in the river-estuarine transition zone. A major integrated measurement programme is now largely complete. New data are being analysed to understand which soil properties have greatest influence on above and below-ground productivity including plant traits and how microbial processing is controlled by stoichiometry and nutrient priming. Within the stream network, new understanding is being produced on the in-river algal and whole ecosystem (metabolic) response to CNP additions and the factors affecting the fate and cycling of organic matter. In the estuary, initial results indicate a subsurface jet is causing stratification and a velocity anomaly has been observed. Both are important in terms of suspended matter transport and floc break-up. An integrated model is being built to describe the soil-atmosphere-vegetation processes which is linked, firstly, to flow and water quality models that describe the CNP flux transport and transformations from the headwaters to the estuary and, secondly, to biodiversity models. The purpose of the integrated model is to quantify how coupled CNP cycles may respond to environmental change and thereby affect C sequestration, water quality and biodiversity in the future. The team are now in the major phase of data synthesis and model development and are interested in linking with similar studies involving coupled CNP cycles across the atmospheric

  17. Relationship between dietary macronutrient intake and the risk of age-related cataract in middle-aged and elderly patients in northeast China

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    Zhi-Quan Lu

    2013-12-01

    Full Text Available AIM: To examine the association between dietary macronutrient intake and the risk of age-related cataract (ARC in middle-aged and elderly men.METHODS:A hospital-based case-control study was conducted from December 2009 to November 2011. Cases (n=360 were patients with cataract aged 45-85 years old, and controls (n=360 were patients who had been admitted to the same hospital for diseases not related with cataract. All subjects were interviewed using a structured interviewer-administrated questionnaire that included information on socio-demographic characteristics, lifestyle habits and detailed medical history, simultaneously, the dietary intakes of nutrients were collected via a valid semi-quantitative food frequency questionnaire (FFQ. The odds ratios (OR and corresponding 95% confidence intervals (CI of three types of ARC were estimated using multiple logistic regression models.RESULTS: After adjusting for multiple potential confounders, total dietary intake of carbohydrate was positively associated with cortical cataract, compared to controls in the lowest quartile, and the OR for cases in the highest quartile of intake was 2.471 (95%CI:1.348-6.043, P=0.027. Higher dietary intakes of protein were protective for posterior subcapsular cataract (PSC (OR=0.528, 95%CI:0.148-0.869, P=0.023. Dietary fat intake was not associated with any type of cataract, however, participants in the highest quartile of polyunsaturated fatty acids intake had 2.7 times the risk of nuclear cataract as did those in the lowest quartile (OR=2.742, 95%CI:1.790-4.200, P=0.033.CONCLUSION: A high intake of carbohydrate and polyunsaturated fatty acid may increase the odds of cortical and nuclear cataract, respectively, whereas high intake of protein, especially animal protein, may protect against PSC cataract. It is possible that dietary changes of target population may reduce the risk of ARC.

  18. Supplemental macronutrients and microbial fermentation products improve the uptake and transport of foliar applied zinc in sunflower (Helianthus annuus L.) plants. Studies utilizing micro X-ray florescence.

    Science.gov (United States)

    Tian, Shengke; Lu, Lingli; Xie, Ruohan; Zhang, Minzhe; Jernstedt, Judith A; Hou, Dandi; Ramsier, Cliff; Brown, Patrick H

    2014-01-01

    Enhancing nutrient uptake and the subsequent elemental transport from the sites of application to sites of utilization is of great importance to the science and practical field application of foliar fertilizers. The aim of this study was to investigate the mobility of various foliar applied zinc (Zn) formulations in sunflower (Helianthus annuus L.) and to evaluate the effects of the addition of an organic biostimulant on phloem loading and elemental mobility. This was achieved by application of foliar formulations to the blade of sunflower (H. annuus L.) and high-resolution elemental imaging with micro X-ray fluorescence (μ-XRF) to visualize Zn within the vascular system of the leaf petiole. Although no significant increase of total Zn in petioles was determined by inductively-coupled plasma mass-spectrometer, μ-XRF elemental imaging showed a clear enrichment of Zn in the vascular tissues within the sunflower petioles treated with foliar fertilizers containing Zn. The concentration of Zn in the vascular of sunflower petioles was increased when Zn was applied with other microelements with EDTA (commercial product Kick-Off) as compared with an equimolar concentration of ZnSO4 alone. The addition of macronutrients N, P, K (commercial product CleanStart) to the Kick-Off Zn fertilizer, further increased vascular system Zn concentrations while the addition of the microbially derived organic biostimulant "GroZyme" resulted in a remarkable enhancement of Zn concentrations in the petiole vascular system. The study provides direct visualized evidence for phloem transport of foliar applied Zn out of sites of application in plants by using μ-XRF technique, and suggests that the formulation of the foliar applied Zn and the addition of the organic biostimulant GroZyme increases the mobility of Zn following its absorption by the leaf of sunflower.

  19. Supplemental macronutrients and microbial fermentation products improve the uptake and transport of foliar applied zinc in sunflower (Helianthus annuus L. plants. Studies utilizing micro X-ray florescence

    Directory of Open Access Journals (Sweden)

    Shengke eTian

    2015-01-01

    Full Text Available Enhancing nutrient uptake and the subsequent elemental transport from the sites of application to sites of utilization is of great importance to the science and practical field application of foliar fertilizers. The aim of this study was to investigate the mobility of various foliar applied Zn formulations in sunflower (Helianthus annuus L. and to evaluate the effects of the addition of an organic biostimulant on phloem loading and elemental mobility. This was achieved by application of foliar formulations to the blade of sunflower (Helianthus annuus L. and high-resolution elemental imaging with micro X-ray fluorescence (μ-XRF to visualize Zn within the vascular system of the leaf petiole. Although no significant increase of total Zn in petioles was determined by ICP-MS, μ-XRF elemental imaging showed a clear enrichment of Zn in the vascular tissues within the sunflower petioles treated with foliar fertilizers containing Zn. The concentration of Zn in the vascular of sunflower pertioles was increased when Zn was applied with other microelements with EDTA (commercial product Kick-Off as compared with an equimolar concentration of ZnSO4 alone. The addition of macronutrients N, P, K (commercial product CleanStart to the Kick-Off Zn fertilizer, further increased vascular system Zn concentrations while the addition of the microbially derived organic biostimulant GroZyme resulted in a remarkable enhancement of Zn concentrations in the petiole vascular system. The study provides direct visualized evidence for phloem transport of foliar applied Zn out of sites of application in plants by using µ-XRF technique, and suggests that the formulation of the foliar applied Zn and the addition of the organic biostimulant GroZyme increases the mobility of Zn following its absorption by the leaf of sunflower.

  20. Energy balance and macronutrient distribution in relation to C-reactive protein and HbA1c levels among patients with type 2 diabetes

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    Hiba Bawadi

    2016-05-01

    Full Text Available Background: Recently growing evidence indicates that obesity and diabetes are states of inflammation associated with elevated circulation of inflammatory mediators. Excess adiposity and oxidative stress, induced by feeding, may also lead to a state of low-grade inflammation. Objective: This study aimed at investigating energy balance and distribution in relation to low-grade inflammation among patients with type 2 diabetes. Design: A cross-sectional study included 198 male and female patients with type 2 diabetes. Patients’ weight, height, waist circumference, total body fat and truncal fat percent, energy, and macronutrient intake were measured. Venous blood specimens were collected, and levels of HbA1c and serum levels of high-sensitivity C-reactive protein (hs-CRP were determined. Results: After adjusting for covariates (body mass index, total body fat, and truncal fat, energy balance was positively correlated with hs-CRP and HbA1c. A positive energy balance was also associated with increased waist circumference and truncal fat percent (p<0.05. Total energy intake, percent energy from fat (p=0.04, and percent energy from proteins (p=0.03, but not percent energy from carbohydrates (p=0.12, were also correlated with higher hs-CRP levels among poorly glycemic-controlled patients. Conclusion: Positive energy balance is associated with elevations in hs-CRP. Increased energy intake and increased percentages of energy from fat and protein are associated with elevated hs-CRP among patients with poor glycemic control.

  1. A statistical approach based on substitution of macronutrients provides additional information to models analyzing single dietary factors in relation to type 2 diabetes in danish adults: the Inter99 study.

    Science.gov (United States)

    Faerch, Kristine; Lau, Cathrine; Tetens, Inge; Pedersen, Oluf Borbye; Jørgensen, Torben; Borch-Johnsen, Knut; Glümer, Charlotte

    2005-05-01

    Most studies analyzing diet-disease relations focus on single dietary factors rather than combining different nutrients into the same statistical model. The objective of this study was to identify dietary factors associated with the probability of having diabetes identified by screening (SDM) in Danish men and women aged 30-60 y. A specific objective was to examine whether an alternative statistical approach could provide additional information to already existing statistical approaches used in nutritional epidemiology. Baseline data from the Danish population-based Inter99 study were used. The dietary intake of 262 individuals with SDM was compared with that of 4627 individuals with normal glucose tolerance (NGT) using 2 different types of multiple logistic regression models adjusted for potential confounders. The first model included single dietary factors, whereas the second model was based on substitution of macronutrients. In the models with single dietary factors, high intakes of carbohydrates, dietary fiber, and coffee were inversely associated with SDM (P < 0.01), whereas high intakes of total fat and saturated fat were positively associated with SDM (P < 0.05). A modest U-shaped association was found between alcohol consumption and SDM (P = 0.10) [corrected] Results from the substitution model showed that when 3% of energy (En%) as carbohydrate replaced 3 En% fat or alcohol, the probability of having SDM decreased by 9 and 10%, respectively (P < 0.01) [corrected] No other macronutrient substitutions resulted in significant associations. Hence, the statistical approach based on substitution of macronutrients provided additional information to the model analyzing single dietary factors.

  2. Market, Regulation, Market, Regulation

    DEFF Research Database (Denmark)

    Frankel, Christian; Galland, Jean-Pierre

    2015-01-01

    This paper focuses on the European Regulatory system which was settled both for opening the Single Market for products and ensuring the consumers' safety. It claims that the New Approach and Standardization, and the Global Approach to conformity assessment, which suppressed the last technical...... barriers to trade in Europe, realized the free movement of products by organizing progressively several orders of markets and regulation. Based on historical and institutional documents, on technical publications, and on interviews, this article relates how the European Commission and the Member States had...... alternatively recourse to markets and to regulations, at the three main levels of the New Approach Directives implementation. The article focuses also more specifically on the Medical Devices sector, not only because this New Approach sector has long been controversial in Europe, and has recently been concerned...

  3. Market, Regulation, Market, Regulation

    DEFF Research Database (Denmark)

    Frankel, Christian; Galland, Jean-Pierre

    2015-01-01

    This paper focuses on the European Regulatory system which was settled both for opening the Single Market for products and ensuring the consumers' safety. It claims that the New Approach and Standardization, and the Global Approach to conformity assessment, which suppressed the last technical...... barriers to trade in Europe, realized the free movement of products by organizing progressively several orders of markets and regulation. Based on historical and institutional documents, on technical publications, and on interviews, this article relates how the European Commission and the Member States had...... alternatively recourse to markets and to regulations, at the three main levels of the New Approach Directives implementation. The article focuses also more specifically on the Medical Devices sector, not only because this New Approach sector has long been controversial in Europe, and has recently been concerned...

  4. Hastes florais de helicônia sob deficiência de macronutrientes Flower stems postharvest characteristics of heliconia under macronutrients deficiency

    Directory of Open Access Journals (Sweden)

    Ana Cecília Ribeiro de Castro

    2007-09-01

    Full Text Available O objetivo deste trabalho foi avaliar características pós-colheita da primeira haste floral de plantas de Heliconia psittacorum x H. spathocircinata Aristeguieta, cultivar Golden Torch, sob deficiência de macronutrientes. O experimento foi conduzido em casa de vegetação, mediante técnica do elemento faltante. As inflorescências produzidas do tratamento sob omissão de N apresentaram coloração laranja-pálido e deformação nas hastes florais. O comprimento e o diâmetro da haste floral e o comprimento da inflorescência foram reduzidos nos tratamentos com omissão de N, P ou K em até 31,23%, em relação ao tratamento completo. A massa de matéria seca e a durabilidade pós-colheita das hastes florais foram reduzidas em 67 e 38,46%, respectivamente, em ambos os tratamentos com omissão de N ou K. As deficiências desses macronutrientes reduziram, ainda, a produção de hastes florais, a partir do segundo perfilho emitido. Hastes florais com maior massa de matéria seca e diâmetro apresentaram maior durabilidade pós-colheita. O teor de carboidrato na parte subterrânea mostrou correlação positiva (0,90 com a massa de matéria seca das hastes florais. Hastes florais com maior teor de carboidratos solúveis nas folhas retardaram a emissão da inflorescência.The objective of this work was to evaluate Heliconia psittacorum x H. spathocircinata Aristeguieta 'Golden Torch' first flower stem morphological and physiological characteristics as well as postharvest longevity, under macronutrients omissions. A greenhouse experiment was conducted under the technique of the lacking element. Inflorescences produced under N omission treatment showed a pale orange color and floral stem deformation. Stem length and diameter as well as inflorescence length were reduced under omission of N, P or K, down to 31.23% when compared to the complete solution treatment. Floral stem dry matter and postharvest longevity were reduced on 67% and 38

  5. Alimentos industrializados en la dieta de los preescolares mexicanos Contribution of processed foods to the energy, macronutrient and fiber intakes of Mexican children aged 1 to 4 years

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    Dinorah González-Castell

    2007-10-01

    Full Text Available OBJETIVOS: Clasificar los alimentos consumidos por preescolares mexicanos, en relación con su proceso de elaboración y temporalidad: a industrializados modernos (IM, b industrializados tradicionales (IT y c no industrializados (NI. MATERIAL Y MÉTODOS: Con base en información del recordatorio de 24 horas de la Encuesta Nacional de Nutrición 1999 en niños de 1-4 años (n=1 070 se analizó la contribución de cada categoría de alimentos en energía, macronutrimentos y fibra. RESULTADOS: La contribución de energía a partir de IM e IT, respectivamente, fue: energía, 17 y 31%; proteína total, 14 y 25%; proteína vegetal, 10 y 10%; proteína animal, 17 y 34%; carbohidratos, 18 y 26%; fibra, 4 y 5%; grasa total, 15 y 41%; grasa saturada, 16 y 52%; y colesterol, 7 y 7 por ciento. CONCLUSIONES: Los alimentos industrializados aportan más de 39% de la energía, proteína animal, carbohidratos y grasas a la dieta de los preescolares mexicanos. Se recomienda la participación de la industria alimentaria para prevenir la mala nutrición infantil en México.OBJECTIVE: To classify the foods consumed by Mexican children 1-4 years in three food categories according to the preparation process and temporality: a Processed Modern Foods (PMF, b Processed Traditional Foods (PTF and c Non-Processed Foods. MATERIAL AND METHODS: Twenty-four-hour dietary recalls were collected from the National Nutrition Survey 1999 in children 1-4 years (n =1070. The contribution of each food category to the total energy, macronutrient and fiber intakes was analyzed. RESULTS: The contribution of PMF and PTF was as follows, respectively: Energy: 17%, 31%; total protein: 14%, 25%; non-animal protein: 10%, 10%; animal protein: 17%, 34%; carbohydrates: 18%, 26%; fiber: 4%, 5%; total fat 15%, 41%; saturated fat 16%, 52%; and cholesterol 7%, 7%. CONCLUSIONS: The contribution of PF to the diets of Mexican children accounts for >39% of energy, total protein, animal protein

  6. Monitoring colony-level effects of sublethal pesticide exposure on honey bees

    Science.gov (United States)

    The effects of sublethal pesticide exposure to honey bee colonies may be significant but difficult to detect in the field using standard visual assessment methods. Here we describe methods to measure the quantities of adult bees, brood and food resources by weighing hives and hive parts, by photogra...

  7. Switch between competition and facilitation within a seasonal scale at colony level in bryophytes.

    Science.gov (United States)

    Spitale, Daniel

    2009-06-01

    The relative importance of positive and negative interaction in species assemblages is thought to be dependent on the harshness of the physical environment. I studied the consistency of this prediction in a field experiment using growth of the target species Warnstorfia exannulata as influenced by the presence or absence of two adjacent species, Sphagnum warnstorfii and Scapania undulata. In particular, I focused on the mechanism by which colony-colony interactions occur, elucidating how the balance of positive and negative interactions changes along a water gradient. Because the natural fluctuations of the environment modify the water gradient, it was expected that the competitive hierarchies of the species would not remain consistent over time. Results indicated that the different hydrological properties of the colonies, thought to be the necessary condition for the appearance of species interactions, were not sufficient to explain the outcome of the species interactions. The switch from competition to facilitation under more stressful conditions was not confirmed along a water stress gradient. In addition, natural climatic fluctuations, by affecting the length of the water gradient, changed the competitive hierarchies of the species on a seasonal scale.

  8. Genetic diversity confers colony-level benefits due to individual immunity

    Science.gov (United States)

    Several costs and benefits arise as a consequence of eusociality and group-living. With increasing group size, spread of disease among nest-mates poses selective pressure on both individual immunity and group-level mechanisms of disease resistance (social immunity). Another factor known to influence...

  9. Sintomas visuais de deficiência de macronutrientes e de boro em abacaxizeiro 'imperial' Visual symptons of macronutrients and boron deficiency in 'imperial' pineapple

    Directory of Open Access Journals (Sweden)

    Maria José Mota Ramos

    2009-03-01

    Full Text Available O objetivo deste trabalho foi caracterizar os sintomas visuais de deficiências de macronutrientes e de boro no abacaxizeiro 'Imperial', e associá-los à diagnose foliar. Os tratamentos: Completo, - N, - P, - K, -Ca, - Mg, - S e - B foram aplicados como soluções nutritivas, em vasos plásticos com 14 kg de areia de praia purificada e uma muda de abacaxi, como unidade experimental. O delineamento foi em blocos casualizados completos, com seis repetições. Os sintomas visuais de deficiência nutricional foram fotografados e descritos durante todo o processo de crescimento e desenvolvimento das plantas. Avaliaram-se, também, as concentrações foliares de N, P, K, Ca, Mg, S e B na folha 'D', aos cinco, sete, nove e 12 meses após o plantio. A deficiência de N causou amarelecimento das folhas da planta e da coroa dos frutos e descoramento da polpa do fruto; a de P, folhas novas vermelho-arroxeadas e frutos com a casca avermelhada; a de K, necrose do ápice das folhas mais velhas e escurecimento da polpa do fruto; a de Mg, necrose na base das folhas da coroa do fruto, e na deficiência de B, frutos com cortiça e rachadura nos frutilhos e entre eles. Apesar dos baixos teores foliares de S e de Ca, na época da colheita dos frutos, não foram observados sintomas visuais de deficiência nos frutos. Os teores foliares no início dos sintomas de deficiência e na época da colheita dos frutos foram, respectivamente: N = 8,7 e 6,8; P = 0,70 e 0,32; K = 11,6 e 3,2; Mg = 0,73 e 0,54 g kg-1, e B = 5,8 e 5,5 mg kg-1.The objective of this study was to characterize the visual symptoms of macronutrients and boron deficiencies in the pineapple 'Imperial', and involve them in the foliar diagnosis. The full treatment, - N, - P - K, - Ca, - Mg, - and S - B was applied as nutrient solutions in plastic pots with 14 kg of purified sand beach and a seedling of pineapple, as an experimental unit . The design was a randomized complete block with six replicates. The

  10. Consumo de energia e macronutrientes por adolescentes de escolas públicas e privadas Energy and macronutrients consumption by adolescents from public private schools

    Directory of Open Access Journals (Sweden)

    Ileana Mourão KAZAPI

    2001-01-01

    Full Text Available O objetivo deste trabalho foi avaliar a adequação do consumo de energia e macronutrientes em adolescentes de escolas públicas (EPU e privadas (EPR do município de Florianópolis, SC. A amostra constou de 797 estudantes: 466 (228 meninas e 238 meninos de EPU e 331 (175 meninas e 156 meninos de EPR. Os dados foram obtidos através do método recordatório de 24 horas. Observou-se que aproximadamente 50% dos adolescentes apresentaram consumo energético insuficiente e mais da metade tiveram um consumo adequado de carboidratos. Entre os adolescentes do sexo masculino que apresentaram alto consumo de carboidratos, houve maior prevalência na rede pública (12,6% EPU e 3,8% EPR. Mais da metade dos estudantes apresentaram alto consumo de proteínas (54,3% EPU e 58,9% EPR, havendo maior prevalência entre os de sexo masculino (61,7% masculino e 50,6% feminino. Apenas 30,5% dos estudantes das EPU e 36,5% das EPR apresentaram consumo adequado de lipídios; ressalta-se o elevado percentual de adolescentes com alto consumo deste nutriente (33,9% EPU e 39,0% EPR. Entre os estudantes que apresentaram baixo consumo de lipídios, houve maior prevalência dos adolescentes do sexo masculino (35,3% masculino e 26,8% feminino, estudantes da EPU (41,6% EPU e 25,6% EPR. Pode-se concluir que o padrão alimentar apresentado por estes adolescentes pode estar associado a riscos para a saúde na vida adulta.The aim of this study was to evaluate the adequacy of energy and macronutrients consumption in adolescent students from public (EPU and private schools (EPR of Florianópolis, state of Santa Catarina. The sample consisted of 797 students: 466 (228 female and 238 male from public schools and 331 (175 female and 156 male from private schools. The informations were obtained using the 24-hour recall method. It was observed that around 50% of the adolescents presented insufficient energy intake and more than 50% of them had adequate consumption of carbohydrates. The

  11. Acúmulo e exportação de macronutrientes pelo híbrido de melancia Tide Accumulation and exportation of macronutrients by watermelon Tide hybrid

    Directory of Open Access Journals (Sweden)

    Leilson Costa Grangeiro

    2004-03-01

    Full Text Available O objetivo do presente trabalho foi determinar o acúmulo e exportação de macronutrientes pela cultura da melancia, híbrido Tide. O experimento foi conduzido no município de Borborema - SP. As amostragens de plantas foram realizadas aos 15, 30, 45, 60 e 75 dias após transplantio (DAT, para determinação da massa seca e do acúmulo e exportação dos nutrientes (N, P, K, Ca, Mg e S. O acúmulo de massa seca foi lento até os 30 DAT, intensificando-se a partir deste período e atingindo, no final do ciclo, a contribuição média da parte vegetativa de 31% e dos frutos de 69%. Até 30 DAT, o acúmulo de nutrientes também foi pequeno, não ultrapassando 2% do total. Com a frutificação, houve forte incremento na quantidade de nutrientes acumulados. O período de maior demanda para N, Ca e Mg foi de 45 a 60 DAT e para P, K e S de 60 a 75 DAT. Do total acumulado, a parte vegetativa foi responsável por 29,6% e os frutos com 70,4%. A ordem decrescente dos nutrientes acumulados pela cultura foi: K>N>Ca>Mg>P>S. Para a produtividade alcançada de 40 t ha-1 observou-se a seguinte exportação de nutrientes pelos frutos: 106,4 kg ha-1 de N, 11,1 kg ha-1 de P, 118,0 kg ha-1 de K, 4,3 kg ha-1 de Ca, 6,8 kg ha-1 de Mg e 6,0 kg ha-1 de S.The objective of this research was to determine under field condition the accumulation and exportation of macronutrients by watermelon plant. The experiment was carried out in the Borborema region, State of São Paulo. The samples were taken at the 15, 30, 45, 60 and 75 days after transplanting (DAT, for dry mass determination and accumulation and exportation of N, P, K, Ca, Mg and S. The dry mass accumulation was slow until 30 DAT, intensifying later with the beginning of the frutification. At the end of the cycle, the average contribution of the vegetative part was of about 31% and of fruits 69%. The accumulation of the nutrients followed the curve of dry mass accumulation. The period of larger demand for the

  12. The Roles of Vitamin A in the Regulation of Carbohydrate, Lipid, and Protein Metabolism

    Directory of Open Access Journals (Sweden)

    Wei Chen

    2014-05-01

    Full Text Available Currently, two-thirds of American adults are overweight or obese. This high prevalence of overweight/obesity negatively affects the health of the population, as obese individuals tend to develop several chronic diseases, such as type 2 diabetes and cardiovascular diseases. Due to obesity’s impact on health, medical costs, and longevity, the rise in the number of obese people has become a public health concern. Both genetic and environmental/dietary factors play a role in the development of metabolic diseases. Intuitively, it seems to be obvious to link over-nutrition to the development of obesity and other metabolic diseases. However, the underlying mechanisms are still unclear. Dietary nutrients not only provide energy derived from macronutrients, but also factors such as micronutrients with regulatory roles. How micronutrients, such as vitamin A (VA; retinol, regulate macronutrient homeostasis is still an ongoing research topic. As an essential micronutrient, VA plays a key role in the general health of an individual. This review summarizes recent research progress regarding VA’s role in carbohydrate, lipid, and protein metabolism. Due to the large amount of information regarding VA functions, this review focusses on metabolism in metabolic active organs and tissues. Additionally, some perspectives for future studies will be provided.

  13. Apparent total tract energy and macronutrient digestibility of one- to three-day-old, adult ground, extruded, and canned chicken-based diets in domestic cats (Felis silvestris catus).

    Science.gov (United States)

    Kerr, K R; Morris, C L; Burke, S L; Swanson, K S

    2014-08-01

    There has been a recent increase in the popularity of feeding unconventional diets, including whole prey diets, to domestic cats (Felis silvestris catus). Data are needed that allow animal caretakers to choose and formulate diets that meet the nutritional requirements of their cats. Our objective was to evaluate the effects of feeding 1- to 3-d-old whole chicks (WHO), ground adult chicken product (GRO), a chicken-based canned diet (CAN), and a chicken-based extruded diet (EXT) on apparent total tract energy and macronutrient digestibility, N balance, and blood metabolites of domestic cats (n = 11). Macronutrient, energy, and moisture concentrations of diets varied greatly (e.g., CP: 35 to 72% DM); however, cats fed all diets maintained BW and N balance. In general, cats fed WHO had lower nutrient digestibility than those fed CAN and EXT. Cats fed GRO had greater nutrient digestibility than cats fed commercial diets. For example, apparent OM and GE digestibility coefficients were greater (P ≤ 0.05) for cats fed CAN (86 and 88%, respectively), EXT (88 and 88%), and GRO (94 and 95%) compared with those fed WHO (83 and 83%) and greater (P ≤ 0.05) for cats fed GRO compared with those fed CAN and EXT. Many blood metabolites were modified by diet, but most remained within reference ranges for domestic cats. Serum cholesterol was elevated above the reference range for all treatments and greater (P ≤ 0.05) for cats fed WHO compared with those fed CAN, EXT, and GRO. Serum creatinine concentrations were above the reference range for all treatments and greater (P ≤ 0.05) for cats fed GRO compared with those fed CAN or WHO. These data indicate that the whole prey tested herein maintained short-term health and are adequately digestible for use in companion animal diets. Research is needed to determine the global and long-term health implications of feeding whole or ground diets to domestic cats, which may be different in terms of macronutrient, energy, and moisture

  14. Efeitos da fertirrigação de N e K2O na absorção de macronutrientes pela gravioleira Effects of fertirrigation of N and K2O on absorption of macronutrients by soursop crop

    Directory of Open Access Journals (Sweden)

    Roberto S. F. de H. Filho

    2006-03-01

    Full Text Available O objetivo deste trabalho foi avaliar o efeito de dosagens de N e K2O via água de irrigação na absorção de macronutrientes pela cultura da gravioleira. O experimento foi realizado no campo experimental da Embrapa Meio-Norte, situado no município de Teresina, PI (05º 05' S, 42º 48' W e 74,4 m de altitude. O delineamento experimental utilizado foi por blocos casualizados, com onze tratamentos e quatro repetições, com parcela útil composta de quatro plantas. Os tratamentos consistiram na aplicação de cinco dosagens de N (20, 120, 200, 280 e 380 kg ha-1 ano-1 combinadas com cinco dosagens de K2O (30, 180, 300, 420 e 570 kg ha-1 ano-1 de acordo com o modelo da matriz experimental Plan Plueba III, além de um tratamento com dosagem zero de ambos os nutrientes. Em nenhum dos tratamentos foi encontrado deficiência de N, K, Mg, S e P nas folhas da gravioleira. As dosagens de N, bem como as suas interações com as dosagens de K2O, não proporcionaram efeito significativo sobre os teores dos macronutrientes nas folhas da gravioleira. As dosagens de K2O influenciaram os teores dos macronutrientes Ca, K e Mg nas folhas da gravioleira.The objetive of this work was to evaluate the effect of doses of N and K2O through irrigation water on the absorption of macronutrients by soursop cultivation. The study was conducted at the experimental field of Embrapa - North, in Teresina, in the State of Piauí, Brazil (5º 05' S, 42º and 48' W. The experimental design was completely randomized blocks with eleven treatments and four repetitions. The treatments consisted in the application of five doses of N (20, 120, 200, 280 and 380 kg ha-1 year-1 combined with five doses of K2O (30, 180, 300, 420 and 570 kg ha-1 year-1 in agreement with the model of experimental matrix Plan Plueba III, besides a treatment with dose zero of both nutrients. No deficiency of N, K, Mg, S, and P in the soursop leaves was found in any treatment. The doses of N did not provide

  15. Asociación entre el consumo de macronutrientes de la dieta y caries en adultos y adultos mayores diabéticos tipo 2 Association between dietary macronutrients and caries in type 2 diabetic adults and elderly

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    RA Giacaman

    2012-08-01

    Full Text Available Objetivos: Se ha reportado una mayor tasa de caries en pacientes con diabetes mellitus tipo 2 (DM, probablemente debido a cambios en los patrones de dieta. El objetivo de este estudio fue determinar si existe una asociación entre la composición de macronutrientes de la dieta y la caries en sujetos con DM. Métodos: Una muestra compuesta por 33 sujetos con DM y 37 controles sin la patología fue examinada para determinar la experiencia de caries mediante el índice COPD y la prevalencia de caries radiculares con ICDAS II. Se aplicó una encuesta de dieta de reporte de 24 horas. Para determinar la composición de la dieta, los alimentos fueron clasificados acorde al contenido de macronutrientes; carbohidratos, proteínas y lípidos (gramos/día, kilocalorías y porcentaje del nutriente/día. Resultados: Los resultados fueron analizados mediante Kruskal-Wallis y Mann-Whitney. Un análisis de correlación y un modelo de regresión lineal se utilizaron para analizar la asociación entre composición de macronutrientes y la tasa de caries coronales y radiculares, con un nivel de significancia del 95%. Resultados: Los pacientes diabéticos tipo 2 mostraron mayor número de dientes perdidos por caries, más dientes obturados y más caries radiculares (pObjectives: Higher caries rates have been reported for type 2 diabetes mellitus patients (DM. Changes in dietary patterns may be partly responsible. The aim of this study was to examine a potential association between dietary macronutrient composition and caries experience in DM patients. Methods: Thirty three adults with DM and thirty seven controls, not affected by DM, were examined to assess coronal caries through DMFT index and root caries by ICDAS II. A 24-hr diet recall survey was used to determine dietary macronutrient composition supplemented with standardized tables and expressed as grams /day, kilocalories/nutrient and percentage of nutrient/day. Results were compared using Kruskal-Wallis and

  16. Acúmulo de macronutrientes por duas cultivares de cebola produzidas em sistema de semeadura direta Accumulation of macronutrients by two onion cultivars on direct sowing system

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    André May

    2008-01-01

    Full Text Available No Brasil, a cebola é considerada a terceira hortaliça mais importante em termos de valor econômico. Contudo, com o advento do uso de novas cultivares híbridas há necessidade do estudo de seu manejo nutricional. Dessa forma, esta pesquisa, realizada em São José do Rio Pardo (SP, de 7 de março a 8 de agosto de 2004, objetivou quantificar o acúmulo de macronutrientes por duas cultivares de cebola estabelecida por semeadura direta. O delineamento experimental utilizado foi o de blocos ao acaso, com três repetições, sendo estudadas as cultivares Optima e Superex. As amostragens de plantas foram realizadas aos 30, 50, 70, 90, 110, 130 e 150 dias após a semeadura. Para uma população de 354.000 plantas ha-1 e uma produtividade estimada de 64,8 t ha-1, a 'Optima' extraiu aos 150 dias após a semeadura: 78,77; 13,04; 75,77; 59,09; 11,70 e 24,38 kg ha-1, respectivamente, de N, P, K, Ca, Mg e S. 'Superex' na mesma população de plantas e uma produtividade de 72 t ha-1 extraiu 64,68; 10,33; 68,28; 65,58; 13,03; 24,74 kg ha-1, respectivamente, de N, P, K, Ca, Mg e S. A cultivar Optima exportou pelo bulbo em relação à planta inteira 49,17% do N, 60,60% do P, 61,16% do K, 41,15% do Ca, 43,56% do Mg e 47,18 do S, o que correspondeu a 38,73; 7,90; 46,34; 24,32; 5,10 e 11,51 kg ha-1 respectivamente. A cultivar Superex exportou pelo bulbo em relação à planta inteira 44,29% do N, 55,85% do P, 62,54% do K, 35,71% do Ca, 31,82% do Mg e 48,80% do S, o que correspondeu a 28,65; 5,77; 42,70; 23,42; 4,15 e 12,07 kg ha-1 respectivamente.Economically, onion is the third more important vegetable in Brazil. As a consequence of the increasing by use of new hybrid varieties, the nutritional management of the crop needs to be adequately known. This research was carried out in São José do Rio Pardo, São Paulo State, Brazil, from March 7 to August 8, 2004. The objective was to quantify, under field conditions, the accumulation of macronutrients by onion

  17. Regulating Transplants

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Legislation to determine brain death is viewed as essential in controlling the organ transplant industry Organ transplant represents a very sensitive and complicated issue. Experts say the temporary administrative regulations recently promulgated by the Central Government are an important step, but relevant laws and regulations must follow. Among these, the

  18. Sulfur nutrient availability regulates root elongation by affecting root indole-3-acetic acid levels and the stem cell niche

    Institute of Scientific and Technical Information of China (English)

    Qing Zhao; Yu Wu; Lei Gao; Jun Ma; Chuan-You Li; Cheng-Bin Xiang

    2014-01-01

    Sulfur is an essential macronutrient for plants with numerous biological functions. However, the influence of sulfur nutrient availability on the regulation of root development remains largely unknown. Here, we report the response of Arabidopsis thaliana L. root development and growth to different levels of sulfate, demonstrating that low sulfate levels promote the primary root elongation. By using various reporter lines, we examined in vivo IAA level and distribution, cel division, and root meristem in response to different sulfate levels. Meanwhile the dynamic changes of in vivo cysteine, glutathione, and IAA levels were measured. Root cysteine, glutathione, and IAA levels are positively correlated with external sulfate levels in the physiological range, which eventual y affect root system architecture. Low sulfate levels also downregulate the genes involved in auxin biosynthesis and transport, and elevate the accumulation of PLT1 and PLT2. This study suggests that sulfate level affects the primary root elongation by regulating the endogenous auxin level and root stem cel niche maintenance.

  19. In vitro growth of Oncidium baueri (Orchidaceae at different macronutrients and sucrose concentrations / Crescimento in vitro de Oncidium baueri (Orchidaceae em diferentes concentrações de macronutrientes e sacarose

    Directory of Open Access Journals (Sweden)

    Jenniffer Aparecida Schnitzer

    2008-07-01

    Full Text Available The propagation in vitro is an important method for orchids reproduction, because the seeds don’t have endosperm and present low germination. The sugar is a important component in medium culture, serving as a source of carbon and energy. The objective of this study was to evaluate the growth in vitro of Oncidium baueri (Orchidaceae in different macronutrients and sucrose concentrations. The treatments consisted: two formulations of the macronutrientes of the MS medium, in complete MS and MS modifed medium with half of the regular concentration of macronutrients, and different sucrose concentrations (30 gL-1, 40 gL-1e 60 gL-1, at pH 5,8. A randomized design with eight replications was used as statistical model and a fask with twenty plants composed each plot. Data were submitted to analysis of variance, complemented by the Tukey test at 5% of signifcance. The following variables were assessed six months after the beguining of the experiment: plant height, root length; number of roots, number of buds, dry mass and total fresh mass. The treatment that showed the best results was 40 gL-1 sucrose in a modifed MS medium with half of regular concentration of macronutrients, for vegetative development and rooting of Oncidium baueri orchid.A propagação in vitro é uma importante técnica na reprodução de orquídeas, devido às sementes serem desprovidas de endosperma e apresentarem uma baixa taxa de germinação na natureza. A sacarose é um componente importante no meio de cultura servindo como fonte de carbono e energia para as plântulas e os macronutrientes são essenciais para a nutrição e crescimento. O presente trabalho teve como objetivo avaliar o crescimento in vitro de Oncidium baueri (Orchidaceae em diferentes concentrações de macronutrientes e sacarose. Os tratamentos consistiram em duas formulações dos macronutrientes do meio Murashige e Skoog (1962, sendo, MS completo e MS modifcado com metade da concentração dos

  20. Gasto energético e ingesta de energía y macronutrientes en mujeres obesas en edad estéril Energy expenditure and energy and macronutrient intake in obese women of fertile age

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    V Esquivel

    2008-12-01

    Full Text Available A 90 mujeres con sobrepeso y obesidad del área de atracción del Programa de Atención Integral en Salud (PAIS se les midió la tasa metabólica basal por calorimetría indirecta y se les evaluó tanto el nivel de actividad física como la ingesta de energía y macronutrientes. Se observó una correlación positiva entre el Índice de Masas Corporal y la tasa metabólica basal de estas mujeres. Aunque se encontró diferencia significativa entre el gasto metabólico basal estimado por la ecuación de Harris-Benedict y el gasto metabólico basal medido por calorimetría indirecta, no se encontró diferencia significativa en el total de energía expedida obtenida por ambos métodos. En estas pacientes con sobrepeso no se encontró diferencia significativa entre el gasto energético total y la ingesta energética diaria obtenida, lo que sugiere un estado de equilibrio energético adaptado a la nueva condición de fisiológica. Según la distribución de macronutrientes fue la grasa la que excedió la recomendación dietética diaria.A group of 90 women with overweight and obesity, residing in the area covered by the Program for Integral Attention in Health (PAIS participated in this study. The following measurements were made: basal metabolic rate by indirect calorimetry, level of physical activity and intake of energy and macronutrients. There was a positive correlation between Body Mass Index and the basal metabolic rate for these women. Although a significant difference was found between the average basal metabolic expenditure of the group, as estimated by the Harris-Benedict equation and average basal metabolic expenditure as measured by indirect calorimetry, there was no significant difference between total energy expenditure as estimated by both methods. No significant difference was found between average energy expenditure and average energy intake for these women, suggesting a state of energy balance which is an adaption to the new

  1. First-Stage Development and Validation of a Web-Based Automated Dietary Modeling Tool: Using Constraint Optimization Techniques to Streamline Food Group and Macronutrient Focused Dietary Prescriptions for Clinical Trials

    Science.gov (United States)

    Morrison, Evan; Sullivan, Emma; Dam, Hoa Khanh

    2016-01-01

    Background Standardizing the background diet of participants during a dietary randomized controlled trial is vital to trial outcomes. For this process, dietary modeling based on food groups and their target servings is employed via a dietary prescription before an intervention, often using a manual process. Partial automation has employed the use of linear programming. Validity of the modeling approach is critical to allow trial outcomes to be translated to practice. Objective This paper describes the first-stage development of a tool to automatically perform dietary modeling using food group and macronutrient requirements as a test case. The Dietary Modeling Tool (DMT) was then compared with existing approaches to dietary modeling (manual and partially automated), which were previously available to dietitians working within a dietary intervention trial. Methods Constraint optimization techniques were implemented to determine whether nonlinear constraints are best suited to the development of the automated dietary modeling tool using food composition and food consumption data. Dietary models were produced and compared with a manual Microsoft Excel calculator, a partially automated Excel Solver approach, and the automated DMT that was developed. Results The web-based DMT was produced using nonlinear constraint optimization, incorporating estimated energy requirement calculations, nutrition guidance systems, and the flexibility to amend food group targets for individuals. Percentage differences between modeling tools revealed similar results for the macronutrients. Polyunsaturated fatty acids and monounsaturated fatty acids showed greater variation between tools (practically equating to a 2-teaspoon difference), although it was not considered clinically significant when the whole diet, as opposed to targeted nutrients or energy requirements, were being addressed. Conclusions Automated modeling tools can streamline the modeling process for dietary intervention trials

  2. Efeito da adubação fosfatada sobre o crescimento e teor de macronutrientes de mudas de pinhão manso Phosphorus fertilization on growth and contents of macronutrients in Jatropha curcas seedlings

    Directory of Open Access Journals (Sweden)

    Rosiane de Lourdes Silva de Lima

    2011-12-01

    Full Text Available A adição de fósforo na composição do substrato para produção de mudas ajuda as raízes e as plântulas a crescerem mais rapidamente, aumenta a resistência aos estresses ambientais e doenças e melhora ainda a eficiência no uso de nutrientes e da água em várias espécies vegetais. Objetivou-se, com este estudo, avaliar o efeito da adição de superfosfato simples no substrato sobre o crescimento e teor foliar de macronutrientes de mudas de pinhão manso (Jatropha curcas. O substrato contendo material de solo e composto de lixo recebeu as doses de 0; 2,5; 5,0; 7,5; 10 e 12,5 kg m-3 de superfosfato simples. As mudas foram avaliadas 30 dias após o plantio. O crescimento máximo das plantas de pinhão manso foi observado com a adição de superfosfato simples ao substrato em doses estimadas na faixa de 5 a 8 kg m-3 de substrato. O fertilizante fosfatado favoreceu o crescimento principalmente de raízes e área foliar e propiciou aumento do teor de todos os macronutrientes no tecido vegetal, exceto o cálcio.The addition of phosphorous to the substrate for the production of seedlings promotes faster growth of both root and shoots, increases tolerance to environmental stress and diseases, and even improves the efficiency of nutrient and water use in several plant species. This experiment aimed to study the effect of the addition of simple superphosphate to the substrate on the growth and macronutrient levels in the contents of seedlings of Jatropha curcas. A substrate containing soil and urban-waste compost was modified by the addition of simple superphosphate in 0; 2.5; 5.0; 7.5; 10.0 and 12.5 kg m-3 amounts. The seedlings were evaluated 30 days after planting. Maximum growth of the Jatropha plants was observed for the simple superphosphate added in estimated amounts in the range of 5 to 8 kg m-3. The phosphorus fertilization especially favored the growth of leaf-area and roots, and promoted increase in contents of all macronutrient except

  3. NORM regulations

    Energy Technology Data Exchange (ETDEWEB)

    Gray, P. [ed.

    1997-02-01

    The author reviews the question of regulation for naturally occuring radioactive material (NORM), and the factors that have made this a more prominent concern today. Past practices have been very relaxed, and have often involved very poor records, the involvment of contractors, and the disposition of contaminated equipment back into commercial service. The rationale behind the establishment of regulations is to provide worker protection, to exempt low risk materials, to aid in scrap recycling, to provide direction for remediation and to examine disposal options. The author reviews existing regulations at federal and state levels, impending legislation, and touches on the issue of site remediation and potential liabilities affecting the release of sites contaminated by NORM.

  4. Effects of eating frequency, snacking, and breakfast skipping on energy regulation: symposium overview.

    Science.gov (United States)

    McCrory, Megan A; Campbell, Wayne W

    2011-01-01

    The ASN hosted a symposium entitled "Eating Patterns and Energy Balance: A Look at Eating Frequency, Snacking, and Breakfast Omission" at the Experimental Biology 2009 annual meeting on April 19, 2009, in New Orleans, LA. The symposium was chaired by Megan McCrory and co-chaired by Wayne Campbell, both from Purdue University. The goal of the symposium was to bring together experts to provide an overview of research on the potential role of eating patterns in the development of overweight and obesity. Studies on eating frequency, snacking, and breakfast skipping were highlighted. In particular, evidence both for and against their roles were discussed, methodological issues that underlie controversies were addressed, and suggested future directions for research were outlined. Appetite regulation and hormonal effects were also reviewed. Megan McCrory introduced the session then discussed studies on eating frequency and energy regulation in free-living adults consuming self-selected diets. Heather Leidy summarized the state of the research on eating frequency and energy regulation in adults from controlled feedings studies. Didier Chapelot discussed various usages of "snack" and argued for a physiological basis to distinguish snacks from meals. Mark Pereira presented information on the effects of breakfast skipping and the macronutrient composition of breakfast in energy regulation and mood. A panel discussion/question and answer session ended the symposium. The symposium was videotaped and can be viewed at www.nutrition.org.

  5. Physiological framework for the regulation of quorum sensing-dependent public goods in Pseudomonas aeruginosa.

    Science.gov (United States)

    Mellbye, Brett; Schuster, Martin

    2014-03-01

    Many bacteria possess cell density-dependent quorum-sensing (QS) systems that often regulate cooperative secretions involved in host-microbe or microbe-microbe interactions. These secretions, or "public goods," are frequently coregulated by stress and starvation responses. Here we provide a physiological rationale for such regulatory complexity in the opportunistic pathogen Pseudomonas aeruginosa. Using minimal-medium batch and chemostat cultures, we comprehensively characterized specific growth rate-limiting macronutrients as key triggers for the expression of extracellular enzymes and metabolites directly controlled by the las and rhl QS systems. Expression was unrelated to cell density, depended on the secreted product's elemental composition, and was induced only when the limiting nutrient was not also a building block of the product; rhl-dependent products showed the strongest response, caused by the largely las-independent induction of the regulator RhlR and its cognate signal. In agreement with the prominent role of the rhl system, slow growth inverted the las-to-rhl signal ratio, previously considered a characteristic distinguishing between planktonic and biofilm lifestyles. Our results highlight a supply-driven, metabolically prudent regulation of public goods that minimizes production costs and thereby helps stabilize cooperative behavior. Such regulation would be beneficial for QS-dependent public goods that act broadly and nonspecifically, and whose need cannot always be accurately assessed by the producing cell. Clear differences in the capacities of the las and rhl systems to integrate starvation signals help explain the existence of multiple QS systems in one cell.

  6. Physical Activity Plays an Important Role in Body Weight Regulation

    Directory of Open Access Journals (Sweden)

    Jean-Philippe Chaput

    2011-01-01

    Full Text Available Emerging literature highlights the need to incorporate physical activity into every strategy intended to prevent weight gain as well as to maintain weight loss over time. Furthermore, physical activity should be part of any plan to lose weight. The stimulus of exercise provides valuable metabolic adaptations that improve energy and macronutrient balance regulation. A tight coupling between energy intake and energy expenditure has been documented at high levels of physical exercise, suggesting that exercise may improve appetite control. The regular practice of physical activity has also been reported to reduce the risk of stress-induced weight gain. A more personalized approach is recommended when planning exercise programs in a clinical weight loss setting in order to limit the compensatory changes associated to exercise-induced weight loss. With modern environment promoting overeating and sedentary behavior, there is an urgent need for a concerted action including legislative measures to promote healthy active living in order to curb the current epidemic of chronic diseases.

  7. Faixas críticas de teores foliares de macronutrientes em mudas de cafeeiro (Coffea arabica L. produzidas em tubetes Critical ranges of macronutrient content in leaves of coffee seedlings (Coffea arabica L. grown in plastic pots

    Directory of Open Access Journals (Sweden)

    Sergio Moraes Gonçalves

    2009-06-01

    Full Text Available Conduziu-se este trabalho, com o objetivo de determinar os teores foliares de macronutrientes em mudas de cafeeiro produzidas em tubetes. O experimento foi conduzido em viveiro localizado no Setor de Cafeicultura do Departamento de Agricultura da Universidade Federal de Lavras (UFLA, no período de maio de 2003 a janeiro de 2004. Foi utilizado o delineamento de blocos casualizados em esquema fatorial simples 6 x 3 com quatro blocos, sendo seis níveis de adubação do substrato (50, 75, 100, 125, 150 e 200% da dose padrão de Osmocote por m³ de substrato e três estádios de desenvolvimento das plantas: 3, 4 e 5 pares de folhas. Foram avaliadas as seguintes características: altura de planta (cm, diâmetro de caule (mm, área foliar (cm², massa seca de raiz (g, massa seca de caule (g, massa seca das folhas (g, massa seca de parte aérea (g, massa seca total (g e concentrações foliares de: N, P, K, Ca, Mg, S. As faixas críticas de teores obtidas para macronutrientes são as seguintes: nitrogênio (2,26 a 2,62 dag/Kg; fósforo (0,22 a 0,25 dag/Kg; potássio (2,59 a 2,92 dag/Kg; cálcio (0,69 a 0,76 dag/Kg; magnésio (0,11 a 0,12 dag/Kg; enxofre (0,15 a 0,24 dag/Kg. Além disso, constatou-se que o estádio de 4 pares de folhas verdadeiras é o ideal para a coleta de folhas visando à avaliação do estado nutricional das mudas.The aim of this study was to determinate the macronutrient content in leaves of coffee seedlings grown in plastic pots. The experiment was carried out at a greenhouse located in the coffee research area at the Agronomy Department of Lavras Federal University from May 2003 to January 2004. We used a block design in a sample factorial 6 x 3 with four blocks, where the substrate was treated with six levels of fertilization (50, 75, 100, 125, 150, and 200% of standard fertilization with Osmocote for m³ substrate and the evaluations were performed at three stages of development (sampling times: three, four, and five pairs of

  8. Crescimento de mudas de angico-vermelho (Anadenanthera macrocarpa (Benth. Brenan sob diferentes doses de macronutrientes Growth of angico vermelho (Anadenanthera macrocarpa (Benth. Brenan seedlings under different macronutrient doses

    Directory of Open Access Journals (Sweden)

    Elzimar de Oliveira Gonçalves

    2008-12-01

    Full Text Available Neste trabalho, objetivou-se avaliar, por meio de características morfológicas, o efeito de doses de macronutrientes no crescimento e desenvolvimento de mudas de angico- vermelho (Anadenanthera macrocarpa (Benth. Brenan produzidas em amostras de três classes de solo (Argissolo Vermelho-Amarelo, Latossolo Vermelho-Amarelo álico e Latossolo Vermelho-Amarelo distrófico. As mudas foram plantadas em vasos com capacidade para 2,1 dm³. O experimento foi conduzido no período de dezembro de 2004 a maio de 2005. Os tratamentos foram delimitados segundo uma matriz baconiana, em que se variaram os macronutrientes em três doses diferentes, mais dois tratamentos adicionais (zero e base, com quatro repetições. As fontes de N, K e S foram parceladas em quatro vezes (0-30-60-90 dias. Em termos gerais, o maior crescimento das plantas ocorreu no Latossolo Vermelho-Amarelo álico. O nutriente que mais surtiu efeitos significativos foi o P, sendo recomendadas doses de 150 a 250 mg dm-3. Para a aplicação de N, recomendam-se doses mínimas de 50 mg/dm³. A aplicação de S deve ser de 20 a 80 mg dm-3. As respostas à aplicação dos demais nutrientes (Ca, Mg e K, em muitos casos, não ocorreu, evidenciando-se que a espécie tem baixo requerimento por eles. Entretanto, partindo desse estudo, sugerem-se novos estudos com os nutrientes K e Ca, para produção de mudas da referida espécie nesses solos.This work aimed to evaluate, by means of morphological characteristics, the effect of macronutrient doses on the growth of angico vermelho (Anadenanthera macrocarpa (Benth. Brenan seedlings cultivated in three soils (Red Yellow Argisol, Red Yellow Dystrophic Latosol and Red Yellow alic Latosol. The seedling were sown in vases with capacity of 2.1 dm³ . The experiment was carried out from December 2004 to June 2005. The treatments were delimited according to a Baconian matrix, with macronutrients varying in three different doses, plus two additional treatments

  9. High-resolution mapping of a genetic locus regulating preferential carbohydrate intake, total kilocalories, and food volume on mouse chromosome 17.

    Directory of Open Access Journals (Sweden)

    Rodrigo Gularte-Mérida

    Full Text Available The specific genes regulating the quantitative variation in macronutrient preference and food intake are virtually unknown. We fine mapped a previously identified mouse chromosome 17 region harboring quantitative trait loci (QTL with large effects on preferential macronutrient intake-carbohydrate (Mnic1, total kilcalories (Kcal2, and total food volume (Tfv1 using interval-specific strains. These loci were isolated in the [C57BL/6J.CAST/EiJ-17.1-(D17Mit19-D17Mit50; B6.CAST-17.1] strain, possessing a ∼ 40.1 Mb region of CAST DNA on the B6 genome. In a macronutrient selection paradigm, the B6.CAST-17.1 subcongenic mice eat 30% more calories from the carbohydrate-rich diet, ∼ 10% more total calories, and ∼ 9% more total food volume per body weight. In the current study, a cross between carbohydrate-preferring B6.CAST-17.1 and fat-preferring, inbred B6 mice was used to generate a subcongenic-derived F2 mapping population; genotypes were determined using a high-density, custom SNP panel. Genetic linkage analysis substantially reduced the 95% confidence interval for Mnic1 (encompassing Kcal2 and Tfv1 from 40.1 to 29.5 Mb and more precisely established its boundaries. Notably, no genetic linkage for self-selected fat intake was detected, underscoring the carbohydrate-specific effect of this locus. A second key finding was the separation of two energy balance QTLs: Mnic1/Kcal2/Tfv1 for food intake and a newly discovered locus regulating short term body weight gain. The Mnic1/Kcal2/Tfv1 QTL was further de-limited to 19.0 Mb, based on the absence of nutrient intake phenotypes in subcongenic HQ17IIa mice. Analyses of available sequence data and gene ontologies, along with comprehensive expression profiling in the hypothalamus of non-recombinant, cast/cast and b6/b6 F2 controls, focused our attention on candidates within the QTL interval. Zfp811, Zfp870, and Btnl6 showed differential expression and also contain stop codons, but have no known biology

  10. Macronutrient intake in advanced age: Te Puāwaitanga o Ngā Tapuwae Kia ora Tonu, Life and Living in Advanced Age: A Cohort Study in New Zealand (LiLACS NZ).

    Science.gov (United States)

    Wham, Carol; Teh, Ruth; Moyes, Simon A; Rolleston, Anna; Muru-Lanning, Marama; Hayman, Karen; Adamson, Ashley; Kerse, Ngaire

    2016-09-01

    As part of the 12-month follow-up of the longitudinal cohort study, Life and Living in Advanced Age: A Cohort Study in New Zealand, dietary intake was assessed in 216 Māori and 362 non-Māori octogenarians using repeat 24-h multiple pass recalls. Energy and macronutrient intakes were calculated, and food items reported were allocated to food groups used in the New Zealand Adult Nutrition Survey (NZANS). Intakes were compared with the nutrient reference values (NRV) for Australia and New Zealand. The median BMI was higher for Māori (28·3 kg/m2) than for non-Māori (26·2 kg/m2) P=0·007. For Māori, median energy intake was 7·44 MJ/d for men and 6·06 MJ/d for women with 16·3 % energy derived from protein, 43·3 % from carbohydrate and 38·5 % from fat. Median energy intake was 7·91 and 6·26 MJ/d for non-Māori men and women, respectively, with 15·4 % of energy derived from protein, 45 % from carbohydrate and 36·7 % from fat. For both ethnic groups, bread was the top contributor to energy and carbohydrate intakes. Protein came from beef and veal, fish and seafood, bread, milk and poultry with the order differing by ethnic groups and sex. Fat came mainly from butter and margarine. Energy-adjusted protein was higher for Māori than non-Māori (P=0·049). For both ethnic groups, the median energy levels were similar, percent carbohydrate tended to be lower and percent fat higher compared with adults aged >70 years in NZANS. These unique cross-sectional data address an important gap in our understanding of dietary intake in this growing section of our population and highlight lack of age-appropriate NRV.

  11. The excesive intake of macronutrients: does it influence the sportive performances of young cyclists? La excesiva ingesta de macronutrientes: ¿influye en el rendimiento deportivo de jóvenes ciclistas?

    Directory of Open Access Journals (Sweden)

    J. L. Sánchez-Benito

    2007-08-01

    Full Text Available The purpose was to determine whether 34 young Spanish males belonging to a cyclist team, follows the optimal macronutrients intake based on the ecommended dietary guidelines. The deficits in nutrition jeopardise the sportive performances, but what about the diets with excessive intake of macronutrients? Furthermore, is there an association between their sportive achievements and the psychological profile? Surely, but the problem is to determine which psychological variables are involved. Method: Nutritional evaluation based on Nutrients intake questionnaire of 7 consecutive days. Results: Cyclists consume an excessive quantity of proteins and lipids in their diets. The average consumption of proteins is 16,36% of their caloric intake (the recommended quantity is less than 10%. The average consumption of fats is 38,71% (the recommended is less than 30%. The same tendency is found in the homologous Spanish young people of the enKID study, where the percentage of energy from fat and saturated fat is much higher than the recommended one. The cyclists consume insufficient quantities of carbohydrates (average is 44, 94% of their caloric intake, the recommended is more than 60%, therefore the reload of their glycogen stores may not be complete on each competition stage. No association has been found between the excessive intake of referred macronutrients and the achieved sport performances. Conclusion: This work contributes to the knowledge of the diets of very active young cyclists. Excessive intake of proteins and fats do not jeopardise their sportive performances. The commonly studied psychological variables in sport, are not determinant of sportive achievements of young cyclists; additional work is needed to determine the psychological profile playing a determinant role in success of young cyclists.El propósito ha sido determinar si un equipo de 34 ciclistas españoles jóvenes sigue las pautas recomendadas en la ingesta de macronutrientes. El d

  12. Ghrelin levels are not regulated by recombinant leptin administration and/or three days of fasting in healthy subjects.

    Science.gov (United States)

    Chan, Jean L; Bullen, John; Lee, Jennifer H; Yiannakouris, Nikos; Mantzoros, Christos S

    2004-01-01

    Ghrelin, a stomach-derived orexigenic peptide, and leptin, a fat-derived anorexigenic hormone, act primarily in the hypothalamus to regulate energy homeostasis and have been reported to be regulated in opposite directions by acute and chronic changes in nutritional state. Nutritional, anthropometric, and hormonal predictors of circulating ghrelin have not yet been fully elucidated, and whether ghrelin is regulated by leptin in humans remains unknown. To address these questions, we performed cross-sectional and interventional studies. In 120 healthy men and women, ghrelin was negatively associated with leptin as well as overall and central adiposity, but not with total energy or specific macronutrient intake. The sexual dimorphism in ghrelin levels (higher levels in women than in men) and the negative correlation between ghrelin and insulin are largely mediated by central adiposity. In six lean men, complete fasting for 3 d resulted in a low leptin state without a major change in fat mass and abolished the meal-related secretory pattern of ghrelin without increasing 24-h ghrelin levels. In addition, recombinant human leptin administration in physiological and pharmacological doses did not regulate ghrelin over several hours to a few days. These data do not support a role for regulation of circulating ghrelin by leptin levels independently of changes in adiposity and suggest that the leptin and ghrelin systems for energy homeostasis function independently of each other in healthy humans.

  13. Colony-level variation in pollen collection and foraging preferences among wild-caught bumble bees (Hymenoptera: Apidae).

    Science.gov (United States)

    Saifuddin, Mustafa; Jha, Shalene

    2014-04-01

    Given that many pollinators have exhibited dramatic declines related to habitat destruction, an improved understanding of pollinator resource collection across human-altered landscapes is essential to conservation efforts. Despite the importance of bumble bees (Bombus spp.) as global pollinators, little is known regarding how pollen collection patterns vary between individuals, colonies, and landscapes. In this study, Vosnesensky bumble bees (Bombus vosnesenskii Radoszkowski) were collected from a range of human-altered and natural landscapes in northern California. Extensive vegetation surveys and Geographic Information System (GIS)-based habitat classifications were conducted at each site, bees were genotyped to identify colony mates, and pollen loads were examined to identify visited plants. In contrast to predictions based on strong competitive interactions, pollen load composition was significantly more similar for bees captured in a shared study region compared with bees throughout the research area but was not significantly more similar for colony mates. Preference analyses revealed that pollen loads were not composed of the most abundant plant species per study region. The majority of ranked pollen preference lists were significantly correlated for pairwise comparisons of colony mates and individuals within a study region, whereas the majority of pairwise comparisons of ranked pollen preference lists between individuals located at separate study regions were uncorrelated. Results suggest that pollen load composition and foraging preferences are similar for bees throughout a shared landscape regardless of colony membership. The importance of native plant species in pollen collection is illustrated through preference analyses, and we suggest prioritization of specific rare native plant species for enhanced bumble bee pollen collection.

  14. Estimativa do consumo de energia e de macronutrientes no domicílio e na escola em pré-escolares Estimation of energy and macronutrient intake at home and in the kindergarten programs in preschool children

    Directory of Open Access Journals (Sweden)

    Juliana Rombaldi Bernardi

    2010-02-01

    Full Text Available OBJETIVO: Estimar o consumo de energia e de macronutrientes no domicílio e na escola em tempo integral em crianças de 2 a 6 anos e pesquisar diferenças no consumo entre as crianças de escolas públicas e particulares. MÉTODOS: Estudo transversal realizado com 362 pré-escolares em Caxias do Sul (RS. O estado nutricional foi avaliado pela razão peso para estatura. O consumo na escola foi avaliado por meio do método de pesagem direta individual dos alimentos consumidos pelas crianças e, no domicílio, por meio do método de registro alimentar realizado pelos pais ou responsáveis. Para as análises estatísticas utilizou-se o teste U de Mann-Whitney (p OBJECTIVE: To estimate the energy and macronutrient intake at home and at all-day in the kindergarten programs in children aged 2 to 6 and to investigate differences in consumption and intake between children at public and private kindergartens. METHODS: This was a cross-sectional study of 362 preschool children from Caxias do Sul, Brazil. Nutritional status was assessed in terms of weight to height ratios. Foods consumed in the kindergarten were evaluated by weighing the actual foods eaten by the children and home intakes were calculated from a food diary kept by parents or guardians. Statistical analyses were performed using the Mann-Whitney U test (p < 0.05. RESULTS: It was found that 28 children (7.7% were overweight, 92 (25.4% were at risk of becoming overweight and seven (1.9% were classified as having wasting. Analysis of 24-hour nutritional intake demonstrated that 51.3% of the energy, 60.3% of the lipids and 51.6% of the proteins consumed by children were eaten at home, despite the children spending the whole day in the kindergarten programs. Preschool children at kindergartens ate greater quantities of energy (p = 0.001, carbohydrates (p < 0.001, and lipids (p = 0.04 than did children at public kindergartens, but their total daily intakes were similar, irrespective of which type of

  15. Níveis de alumínio e acúmulo de macronutrientes em porta-enxertos cítricos em cultivo hidropônico Aluminum levels and macronutrient accumulation in citrus rootstocks in hydroponic solution

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    Carlos Henrique dos Santos

    1999-01-01

    Full Text Available O presente trabalho teve como objetivo avaliar a influência de diferentes níveis de alumínio no acúmulo de macronutrientes pelos porta-enxertos cítricos limoeiro Cravo e citrumeleiro Swingle, sob cultivo hidropônico. Os tratamentos utilizados em condições de casa de vegetação seguiram o delineamento estatístico inteiramente casualizado, com 3 repetições, em parcelas subdivididas. Os níveis de alumínio utilizados foram: 0, 7,5, 15, 22,5 e 30 mg L-1, na forma de AlCl3.6 H2O. Determinaram-se o acúmulo de N, P, K, Ca, Mg, S e do Al da matéria seca vegetal, relacionando-os com os pesos da matéria seca da parte aérea (folhas e caule e raízes durante o período de 84 dias, com coletas de plantas a cada 14 dias. Conclui-se que, com adição a partir de 7,5 mg L-1 de alumínio em solução nutritiva ocorreram alterações fisiológicas e reduções significativas no acúmulo de macronutrientes associado à redução nos pesos da matéria seca das folhas, caule e raízes das plantas de citrumelo Swingle.The aim of this research was to study the influence of different levels of aluminum on macronutrient contents of citrus rootstocks of the `Rangpur' lime and the `Swingle' citrumelo, in hydroponic solution. The treatments, established under greenhouse conditions, followed a completely randomized experimental design, with 3 replications, distributed in split-plots. The levels of aluminum were: 0; 7.5; 15; 22.5 and 30 mg L-1, applied as AlCl3.6 H2O. The evaluated chemical plant parameters were the concentrations of N, P, K, Ca, Mg, S, Al and dry weight of leaves, stem and root system. The results showed that with adition of 7.5 mg L-1 of Al to the nutrient solution there was a significant decrese of nutrient contents and a decrese in leave, stem and root system dry weight of `Swingle' citrumelo.

  16. Efeitos da adubação NPK nos teores de macronutrientes das folhas de cana-de-açúcar (cana-soca Leaf macronutrient affected by NPK fertilization in sugar cane ratoon crops

    Directory of Open Access Journals (Sweden)

    Ademar Espironelo

    1986-01-01

    Full Text Available Foram utilizados oito ensaios de adubação NPK, em cana-soca do cultivar CB41-76, conduzidos em diversos solos do Estado de São Paulo, sendo quatro em Latossolo Roxo, um em Latossolo Vermelho-Amarelo textura argilosa, um em Latossolo Vermelho-Amarelo textura média, um em solos Podzolizados de Lins e Marília variação Manilha e outro em variação Lins. Aos quatro meses de idade da cana-soca, amostras de folhas + 3 foram coletadas para fins de análise de macronutrientes. As variações dos teores de macronutrientes foram mais acentuadas entre localidades do que entre doses dos respectivos adubos. Correlações positivas e significativas foram obtidas somente entre os teores de potássio nas folhas e as produções de cana. Devido às variações acentuadas dos teores de macronutrientes nas folhas de cana-soca em relação a diferentes localidades, as seguintes faixas de teores de nutrientes poderão ser, provisoriamente, consideradas como adequadas: N - 1,53 a 2,22%; P-0,14 a 0,20%; K - 1,24 a 1,59%; Ca-0,38 a 0,71%; Mg - 0,11 a 0,20% e S-0,11 a 0,31%.Eight fertilizer experiments with sugarcane ratoon crops (CB41-76 variety were carried out at several soils in the State of São Paulo, Brazil. Four of them were established on the Dusky Red Latosol, one in the clayey textured Red Yellow Latosol, one in a medium textured Dark Red Latosol and two in the Podzolized soils from calcareous sandstones sediments. Four month old leaves of position +3 were collected and analyzed for macronutrients. Considering the wide variation among localities, the following ranges of leaf nutrient contents were tentatively taken as adequate for sugarcane ratoon crops: N - 1.53 to 2.22%; P - 0.14 to 0.20%; K - 1.24 to 1.59%; Ca - 0.38 to 0.71%; Mg - 0.11 to 0.20% and S - 0.11 to 0.31%.

  17. Efeito do composto orgânico e compactação do solo no milho e nutrientes do solo Effect of compaction and organic compost application on corn biomass and macronutrient contents in soil

    Directory of Open Access Journals (Sweden)

    Pedro N. F. Rodrigues

    2011-08-01

    Full Text Available Quando bem aproveitados, os resíduos orgânicos conduzem a grandes benefícios disponibilizando matéria orgânica e nutriente ao solo. Neste contexto, objetivou-se, no presente estudo, verificar o efeito da aplicação de doses de composto orgânico em dois solos submetidos a diferentes compactações na biomassa seca do milho. Para isto se aplicaram, em 54 vasos, três doses de composto orgânico nas quantidades 0 (testemunha, 40 e 80 g dm-3, em um Argissolo Vermelho Escuro e em um outro Argissolo Vermelho-Amarelo, coletados no horizonte Ap, no perfil de 0 a 0,20 m, conduzidos em três diferentes densidades (1,3; 1,5 e 1,7 kg dm-3 e três repetições. A cultura utilizada no experimento foi o milho (Zea mays, cultivar Itapuã 700. As variáveis avaliadas foram biomassa seca da parte aérea do milho (MS e os teores de N, P, K, Ca, Mg e carbono orgânico total (COT do solo. Os resultados obtidos indicaram que a aplicação do composto orgânico causou efeito significativo sobre os teores dos macronutrientes disponíveis e COT e a compactação do solo pouco afetou as variáveis estudadas.When well utilized, organic residues lead to great benefits making organic matter and nutrients available in soils. In this context, the present study had the objective to evaluate the effect of organic compost doses on two soils submitted to different compactions and on corn biomass. Thus, in 54 pots were added three doses 0, 40 or 80 g dm-3 of organic compost in a Dark Red Argisoil or Red Yellowish Argisoil, collected from the Ap horizon (depth of 0 to 0.20 m, submitted to three compaction degrees (1.3, 1.5 and 1.7 kg dm-3, with three replications. The crop used in the experiment was corn (Zea mays, cultivar Itapuã 700. The plant growth, and content of N, P, K, Ca, Mg and organic carbon (TOC in soil were evaluated. The results point out that the organic compost application significantly affected soil OC and macronutrients, but little effect was induced by

  18. A low-fat vegan diet elicits greater macronutrient changes, but is comparable in adherence and acceptability, compared with a more conventional diabetes diet among individuals with type 2 diabetes.

    Science.gov (United States)

    Barnard, Neal D; Gloede, Lise; Cohen, Joshua; Jenkins, David J A; Turner-McGrievy, Gabrielle; Green, Amber A; Ferdowsian, Hope

    2009-02-01

    macronutrient intake, a low-fat, vegan diet has an acceptability similar to that of a more conventional diabetes diet. Acceptability appears to be no barrier to its use in medical nutrition therapy.

  19. Teores de macro e micronutrientes e a relação c/n de várias espécies de plantas daninhas Contents of macronutrients and micronutrients and CN relation of several weed species

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    Luciano S. Souza

    1999-04-01

    Full Text Available O objetivo do presente trabalho foi determinar os teores de nutrientes (N, P, K, Ca, Mg, S, Cu, Zn, Fe e Mn e a relação C/N, presentes na matéria seca da parte aérea das seguintes espécies de plantas daninhas: Ageratum conyzoides L., Amaranthus lividus L., Bidens pilosa L., Brachiaria decumbens Stapf., Brachiaria plantaginea (Link Hitchc., Senna occidentalis (L. Link., Commelina benghalensis L., Cyperus rotundus L., Digitaria horizontalis Willd., Euphorbia heterophylla L., Indigofera truxillensis H.B.K., Ipomoea acuminata Roem. et Schult, Panicum maximum Jacq., Raphanus raphanistrum L., Rhynchelytrum repens (Willd. C.E. Hubb., Richardia brasiliensis Gomez e Sida cordifolia L. Os teores de macronutrientes obtidos da matéria seca das plantas daninhas, foram maiores em geral nas dicotiledôneas. Em relação às monocotiledôneas não houve um padrão de comportamento para os micronutrientes. Entretanto, o teores de carbono foram, em média, superiores para todas as monocotiledôneas, sendo que as dicotiledôneas apresentaram relações C/N menores do que as monocotiledôneas.The aim of this work was to determine nutrient contents (N, P, K, Ca, Mg, S, Cu, Zn, Fe and Mn as well as the CN relation found in the dry matter of the aerial parts of the following weeds: Ageratum conyzoides L., Amaranthus lividus L., Bidens pilosa L., Brachiaria decumbens Stapf., Brachiaria plantaginea (Link Hitchc., Senna occidentalis (L. Link., Commelina benghalensis L., Cyperus rotundus L., Digitaria horizontalis Willd., Euphorbia heterophylla L., Indigofera truxillensis H.B.K., Ipomoea acuminata Roem. et Schult, Panicum maximum Jacq., Raphanus raphanistrum L., Rhynchelytrum repens (Willd. C.E. Hubb., Richardia brasiliensis Gomez e Sida cordifolia L. Macronutrient contents got from weeds dry matter were higher in the dycotiledons.Concerning monocotyledons there were no standard of behaviour for micronutrients. However, carbon contents were superior to all

  20. Association of total energy intake and macronutrient consumption with colorectal cancer risk: results from a large population-based case-control study in Newfoundland and Labrador and Ontario, Canada

    Directory of Open Access Journals (Sweden)

    Sun Zhuoyu

    2012-03-01

    Full Text Available Abstract Background Diet is regarded as one of the most important environmental factors associated with colorectal cancer (CRC risk. A recent report comprehensively concluded that total energy intake does not have a simple relationship with CRC risk, and that the data were inconsistent for carbohydrate, cholesterol and protein. The objective of this study was to identify the associations of CRC risk with dietary intakes of total energy, protein, fat, carbohydrate, fiber, and alcohol using data from a large case-control study conducted in Newfoundland and Labrador (NL and Ontario (ON, Canada. Methods Incident colorectal cancer cases (n = 1760 were identified from population-based cancer registries in the provinces of ON (1997-2000 and NL (1999-2003. Controls (n = 2481 were a random sample of residents in each province, aged 20-74 years. Family history questionnaire (FHQ, personal history questionnaire (PHQ, and food frequency questionnaire (FFQ were used to collect study data. Logistic regression was used to evaluate the association of intakes of total energy, macronutrients and alcohol with CRC risk. Results Total energy intake was associated with higher risk of CRC (OR: 1.56; 95% CI: 1.21-2.01, p-trend = 0.02, 5th versus 1st quintile, whereas inverse associations emerged for intakes of protein (OR: 0.85, 95%CI: 0.69-1.00, p-trend = 0.06, 5th versus 1st quintile, carbohydrate (OR: 0.81, 95%CI: 0.63-1.00, p-trend = 0.05, 5th versus 1st quintile and total dietary fiber (OR: 0.84, 95% CI:0.67-0.99, p-trend = 0.04, 5th versus 1st quintile. Total fat, alcohol, saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, and cholesterol were not associated with CRC risk. Conclusion This study provides further evidence that high energy intake may increase risk of incident CRC, whereas diets high in protein, fiber, and carbohydrate may reduce the risk of the disease.

  1. Dietary macronutrient recommendations for optimal recovery post ...

    African Journals Online (AJOL)

    Enrique

    place post-exercise, a positive nitrogen balance is needed in order to allow for ... however, an upper limit for protein ingestion has been set at. 2 g/kg BW/day ... conditions. The drinks ...... exercise during heat stress in men and women. Med Sci ...

  2. [ENERGY AND MACRONUTRIENT INTAKE IN FEMALE ATHLETES].

    Science.gov (United States)

    Bernad Asencio, Laura; Reig García-Galbis, Manuel

    2015-11-01

    Objetivo: determinar la ingesta de macronutrientes adecuada para mejorar el estado nutricional de las mujeres atletas y su rendimiento deportivo. Métodos: se realizó una búsqueda en cuatro bases de datos: EBSCO, Proquest, Pubmed y OvidSP, empleando las palabras clave “protein intake” AND “athletes” y “endurance athletes” AND “nutrition”. Criterios de selección: artículos originales sobre el consumo de proteínas en atletas femeninas (Entre 2009 y 2014), en revistas científicas indexadas. Resultados: se identificaron 722 artículos, de los cuales solo el 1,4% fueron considerados como incluidos. El 100% eran ensayos clínicos finalizados y publicados en el extranjero, el 50% en EE. UU. El 20% eran estudios exclusivos de mujeres atletas y el 80% incluían hombres y mujeres en la muestra. En el 70% de los estudios las mujeres atletas presentaron déficits energéticos; en la ingesta proteica, el 70% cumplieron con las recomendaciones dietéticas; la ingesta de hidratos de carbono fue inadecuada en el 90% de los ensayos clínicos y, en el 50%, las mujeres presentaban una sobreingesta de grasas. Conclusiones: existe una deficiencia de información acerca de la nutrición en mujeres atletas en Europa y a nivel internacional. Las atletas femeninas consumen energía y macronutrientes en menor proporción que los atletas masculinos. No existe consenso en el rango de proteínas recomendado y se encuentran discrepancias en el consumo en función del tipo de ejercicio físico que se realice. Se recomienda llevar a cabo un acuerdo entre instituciones científicas de prestigio sobre la ingesta energética y de macronutrientes en el deporte, especialmente en la mujer.

  3. Is there evidence for a set point that regulates human body weight?

    Science.gov (United States)

    Müller, Manfred J; Bosy-Westphal, Anja; Heymsfield, Steven B

    2010-08-09

    There is evidence for the idea that there is biological (active) control of body weight at a given set point. Body weight is the product of genetic effects (DNA), epigenetic effects (heritable traits that do not involve changes in DNA), and the environment. Regulation of body weight is asymmetric, being more effective in response to weight loss than to weight gain. However, regulation may be lost or camouflaged by Western diets, suggesting that the failure of biological control is due mainly to external factors. In this situation, the body's 'set point' (i.e., a constant 'body-inherent' weight regulated by a proportional feedback control system) is replaced by various 'settling points' that are influenced by energy and macronutrient intake in order for the body to achieve a zero energy balance. In a world of abundance, a prudent lifestyle and thus cognitive control are preconditions of effective biological control and a stable body weight. This idea also impacts future genetic research on body weight regulation. Searching for the genetic background of excess weight gain in a world of abundance is misleading since the possible biological control is widely overshadowed by the effect of the environment. In regard to clinical practice, dietary approaches to both weight loss and weight gain have to be reconsidered. In underweight patients (e.g., patients with anorexia nervosa), weight gain is supported by biological mechanisms that may or may not be suppressed by hyperalimentation. To overcome weight loss-induced counter-regulation in the overweight, biological signals have to be taken into account. Computational modeling of weight changes based on metabolic flux and its regulation will provide future strategies for clinical nutrition.

  4. Estudo comparativo do acúmulo de massa seca e macronutrientes por plantas de milho var. BR-106 e Brachiaria plantaginea Dry matter and macronutrient accumulation by maize and Brachiaria plantaginea

    Directory of Open Access Journals (Sweden)

    L.B. Carvalho

    2007-01-01

    Full Text Available Foram realizados dois experimentos, em casa de vegetação, no Departamento de Biologia Aplicada à Agropecuária da FCAV-UNESP de Jaboticabal, objetivando-se determinar o acúmulo de massa seca e a distribuição e acúmulo de macronutrientes em plantas de milho, no período de outubro de 2000 a fevereiro de 2001, e de capim-marmelada, no período de setembro de 2003 a fevereiro de 2004. Os estudos foram realizados em delineamento experimental inteiramente casualizado, com quatro repetições. As plantas cresceram em vasos com capacidade de sete litros - preenchidos com areia de rio lavada e peneirada - e foram irrigadas diariamente com solução nutritiva. Os tratamentos foram representados pelas épocas de amostragem realizadas a intervalos de 14 dias, a saber: 21, 35, 49, 63, 77, 91, 105, 119 e 133 dias após a emergência (DAE das plantas de milho; e 21, 35, 49, 63, 77, 91, 105, 119, 133 e 147 DAE das plantas de capim-marmelada. O ponto de máximo acúmulo teórico de massa seca deu-se aos 122 DAE para o milho (143,8 g por planta e aos 143 DAE para o capim-marmelada (23,9 g por planta. A taxa de absorção diária dos macronutrientes atingiu maiores valores entre 71 e 104 DAE para o milho e entre 96 e 111 DAE para a planta daninha. Levando-se em conta a média dos valores de pontos de inflexão observados na cultura do milho, aos 85 DAE uma planta de milho acumula, teoricamente, 83,0 g de massa seca; 788,9 mg de N; 137,5 mg de P; 1.385,6 mg de K; 551,8 mg de Ca; 217,9 mg de Mg; e 92,5 mg de S. Enquanto que, no mesmo período, uma planta de B. plantaginea acumula, teoricamente, 9,6 g de massa seca; 127,8 mg de N; 15,9 mg de P; 217,3 mg de K; 43,9 mg de Ca; 58,3 mg de Mg; e 15,8 mg de S.Two trials were conducted under greenhouse conditions at the FCAV/UNESP facilities in Jaboticabal, SP, Brazil, to determine dry matter accumulation, as well as macronutrient distribution and accumulation in maize plants from October 2000 to February 2001, and

  5. Food, energy and macronutrient intake of postmenopausal women from a menopause program Consumo de alimentos, energía y macronutrientes en mujeres postmenopáusicas de un programa de menopausia

    Directory of Open Access Journals (Sweden)

    S. Schoppen

    2005-04-01

    Full Text Available Objective: This study aimed to analyse the food, energy and macronutrient intake of a group of postmenopausal women participating in a health-care-program. Methods: Subjects included were 38 healthy postmenopausal women aged between 46 and 60 years, recruited from the Menopause Program of the Madrid City Council. Physical activity, some anthropometric data and dietary information was obtained using a modified version of the dietary history method, which contained a 24-hour-recall and a food frequency questionnaire covering the preceding month as reference period. Dietary quality indexes, including those of the energy provided by macronutrients, alcohol and fatty acids and PUFA + MUFA/SFA and PUFA/SFA ratios were calculated. Results: This group consumed a diet very similar to the traditional Mediterranean diet. Intake of vegetables (415 ± 165 g/d, fruits (396 ± 178 g/d and fish (131 ± 69 g/d was high and a wide variety of these products was consumed. Potato and cereal (157 ± 76 g/d intake was low. Dairy products, meat, poultry and eggs were only a modest part of this diet. The fat quality (PUFA + MUFA/SFA = 2.26 was satisfactory. Conclusion: The diet of this group of postmenopausal women attending a prevention program closely conforms to current nutritional guidelines. Physical activity, body weight and intake of vegetable foods are adequate and may be very useful to counterbalance the increased risk of several pathologies after menopause. However, consumption of carbohydrate rich foods is lower than recommended. Participation in the menopause healthcare-program is useful for weight control and dietary advice.Objetivo: Analizar la ingesta de alimentos, energía y macronutrientes de un grupo de mujeres postmenopáusicas que participan en un programa de postmenopausia. M��todos: La muestra está formada por 38 mujeres postmenopáusicas de 46 a 60 años de edad, pertenecientes al Programa de Menopausia del Excmo. Ayuntamiento de Madrid. Se

  6. Acúmulo de massa seca e de macronutrientes por plantas de Glycine max e Solanum americanum Accumulation of dry mass and macronutrients by Glycine max and Solanum americanum plants

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    S. Bianco

    2012-03-01

    S.Soybean is one of the main crops in Brazil, but its productivity is very affected by weed competition. Two experiments were carried out in Jaboticabal, SP, Brazil, under greenhouse conditions to determine the accumulation and distribution of dry mass and macronutrients in soybean cv. BR-16, from October 2000 to February 2001, and Solanum americanum plants, from January to May 1995. Plants were grown in seven liter pots filled with river sand substrate and were daily irrigated with nutrient solution. The treatments were constituted by the times of samplings carried out at 14 day intervals, starting 21 days after emergence (DAE. Soybean evaluation was extended to 161 DAE, while S. americanum was extended to 119 DAE. The point of maximum theoretical accumulation of dry mass in soybean occurred at 104 DAE (35.00 g per plant while for S. americanum, it occurred at 143 DAE (179.62 g per plant. From emergence until 49 and 63 DAE, leaves showed higher participation in dry mass accumulation of soybean and S. americanum, respectively. After these periods, an inversion could be observed, with leaves being surpassed by stems for the weeds, and by stems and later, by reproductive structures, for the crop. Macronutrient uptake rate reached higher values between 69 to 87 DAE for soybean and between 105 to 119 DAE for S. americanum. Considering the mean inflexion point values observed in soybean crop, at 75 DAE, it can be evidenced that one soybean plant theoretically accumulated 23.90 g of dry mass, 564.40 mg of N, 7.10 mg of P, 490.80 mg of K, 487.00 mg of Ca, 156.60 mg of Mg and 36.00 mg of S, while one S. americanum plant theoretically accumulated 33.75 g of dry mass, 875.96 mg of N, 88.46 mg of P, 983.54 mg of K, 647.60 mg of Ca, 100.93 mg of Mg, and 42.15 mg of S.

  7. Macronutrient Fluxes of the Litterfall in Chinese Fir Plantation in Response to Simulated Nitrogen Deposition%氮沉降对杉木人工林凋落物大量元素归还量的影响

    Institute of Scientific and Technical Information of China (English)

    刘文飞; 樊后保; 袁颖红; 黄荣珍; 廖迎春; 李燕燕; 沈芳芳

    2011-01-01

    通过野外模拟试验,研究了杉木人工林(Cunninghamia lanceolata)凋落物养分归还对氮沉降增加的响应.试验设计为4种处理,分N0(对照)、N1、N2、N3共4种处理,N沉降量分别为0,60,120,240kgN/(hm2·a).每处理重复3次.通过3 a监测发现,经N0、N1、N2、N3处理,N元素平均年归还量分别为8.49,8.51,9.57,9.37 kg/hm2,P分别为0.74,0.68,0.73,0.72 kg/hm2,K分别为3.57,3.93,4.02,3.98kg/hm2,Ca分别为6.81,6.96,6.76,7.12 kg/hm2,Mg分别为2.12,2.22,2.08,2.30 kg/hm2,相对于N0处理,各水平的氮沉降处理在3 a时间里表现为提高凋落物N归还量的作用,但是增长幅度有下降的趋势,对P元素归还有抑制作用,对K、Ca、Mg元素先期表现为促进其归还量的作用,但在后期逐渐有呈抑制的趋势.各处理凋落物5种元素归还量均在2,4,7月出现3个明显的归还高峰期,最大值均出现在7月份.%A field experiment was conducted to study the effect of simulated nitrogen on nutrient flux of litterfall in a Chinese fir plantation. Urea (CO(NH2)2) was added at three doses, N1, N2 and N3, 60, 120,240 kg N/(hm2 · a), respectively. Based on litterfall collection during 3 years, through litterfall production,the annual N flux to the forest floor under the four treatments (N0, N1, N2 and N3) was estimated, respectively, at 8.49,8.51,9.57,9.37 kg/hm2 ; P at 0.74, 0.68, 0.73,0.72 kg/hm2 ; K at 3. 57, 3.93, 4.02,3.98 kg/hm2 ; Ca at 6.81, 6.96, 6.76,7.12 kg/hm2 ; Mg at 2.12, 2.22, 2.08,2.30 kg/hm2. The data suggested that the annual flux of N elements responded positively to N1, N2 and N3 treatments, compared with the control (N0), but growth rate decreased with the increasing N additions, negatively to P flux. It showed increased flux of K, Ca, and Mg for N1, N2 and N3 treatments firstly, thereafter decreased with the time passing by. The macronutrient flux through litterfall exhibited three pronounced peaks, occurring consistently in February, April and July respectively

  8. Consumo de macronutrientes y estilo de vida en pacientes con trasplante renal que acudieron a un evento deportivo nacional Macronutrients consumption and lifestyle in patients whose received transplant of kidney in The Mexican Institute for Social Security

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    E. Vázquez Pulgar

    2010-02-01

    Full Text Available El transplante renal es la opción terapeútica que más calidad de vida ofrece al enfermo con Insuficiencia renal crónica avanzada. Este trabajo se hizo con el objetivo de conocer el estilo de vida y patrones de consumo de macronutrientes en pacientes del Instituto Mexicano del Seguro Social, que recibieron transplante renal. Se obtuvo información sociodemográfica, antropométrica de 119 individuos postrasplantados de riñón que acudieron a un evento deportivo nacional y se estudió su consumo de macronutrientes a través del recordatorio de 24 hrs. Para evaluar el estilo de vida se utilizó el instrumento IMEVID, este instrumento fue previamente validado y mostró una fiabilidad de 0.681 con el alfa de Cronbach y de 0.685 con el método de Spearman-Brown. El estilo de vida predominante fue el poco favorable el cual se encontró en cerca del 70% de los casos estudiados (p The transplant offer the best quality of life to patients whose suffer from advanced chronic renal failure. This work was undertaken to know the lifestyle and macronutrients consume patterns in patients from the Mexican Institute for Social Security whose received a transplanted kidney . Demographic and anthropometric information were obtained from 119 transplanted patients and consume patterns were obtained from them through the recall of 24 hours. The IMEVID questionnaire was used to assess the lifestyle in this population. This instrument was previously validated for its reliability, its showed a value of 0.681 for alpha of Cronbach and 0.685 for Spearman-Brown test. The 70% of the patients showed less favourable lifestyles and there were no differences between genders. There were significative differences among states of the country where the subjects lived; attending the following domains of the IMEVID questionnaire. Information, physical activity and adjustment to the treatment (p < 0.001. In those States near the american border the BMI was superior to the 25 kg

  9. Macronutrientes em mudas de citros cultivadas em vasos em resposta à adubação NPK Macronutrients in citrus nursery trees grown in pots in response to NPK fertilization

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    Alberto Carlos de Campos Bernardi

    2000-12-01

    Full Text Available Mudas de laranjeira 'Valência' (Citrus sinensis sobre o porta-enxerto de limoeiro 'Cravo' (C. limonia foram cultivadas em vasos com substrato de casca de Pinus, vermiculita e perlita com o objetivo de avaliar-se os efeitos do fornecimento de N, P e K sobre os teores de macronutrientes do porta-enxerto e das mudas. Utilizou-se um esquema de fatorial fracionário (1/55³ com um delineamento em blocos ao acaso. Os tratamentos consistiram em 5 doses (em g por planta de N: 1,25; 6,25; 11,25; 16,25; 21,25; 5 doses de K: 0,42; 3,75; 6,22; 9,34; 12,45; e 5 doses de P: 0,19; 0,89; 1,59; 2,29; 2,99. O N e K foram fornecidos semanalmente, sendo 37,5% da dose para o porta-enxerto. O P foi fornecido totalmente no plantio. Determinaram-se os teores totais de N, P e K, Ca, Mg e S nas folhas novas e velhas, raízes e caule e a extração de N, P e K. Os teores de N relacionaram-se diretamente e os de P e K inversamente com a adubação nitrogenada. Os teores de Ca, Mg e S relacionaram-se positivamente até as doses intermediárias de N utilizadas. Houve efeito inibitório do fertilizante potássico sobre a absorção de Ca e Mg. A acumulação de NPK pelos porta-enxertos foi em torno de 30% pelas raízes e 70% pela parte aérea.'Valencia' sweet orange nursery trees (Citrus sinensis budded on Rangpur lime rootstocks (C. limonia were grown in containers using pine bark, vermiculite and perlite as substracts with the objective of evaluating the NPK fertilization effect on macronutrient levels. The experiment was a complete (1/5 5³ factorial randomized block design. Treatments comprised five concentrations in g per plant of N: 1.25; 6.25; 11.25; 16.25; 21.25; five concnetrations of K: 0.42; 3.75; 6.22; 9.34; 12.45; and five concentration of P: 0.19; 0.89; 1.59; 2.29; 2.99. Nitrogen and K were applieded weekly, and 37.5% of the total fertilization was applied to rootstocks. All P was supplied at planting. Young and old leaves, root and stem total nutrient

  10. Qualidade sensorial dos frutos do abacaxizeiro 'imperial' cultivado em deficiência de macronutrientes e de boro Sensorial quality of the fruits of 'imperial' pineapple cultivated in macronutrient and boron deficiencies

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    Maria José Mota Ramos

    2010-09-01

    of a green house experiment of the North Fluminense State University , in Campos dos Goytacazes, RJ, in the period from 2003 to 2005 to evaluate the effects of the macronutrients and boron deficiencies on the physico- chemical composicion and sensorial quality of fruits. The experimental unit consisted of a 14 L plastic pot filled with purified sand and a seedling of that cultivar. The following treatments were used: complete, - N, - P, - K, - Ca, - Mg, - S and - B, applied as nutrient solutions, in randomized complete blocks, with six replicates. The following characteristics were measured in the fruits: firmness, juice concentration, TA, TSS, TSS/TA, vitamin C, pH, coloration and the sensorial analysis of the pulp. The deficiencies of N and of K increased the pulp firmness but that of S reduced it. The deficiencies of N and S increased the TA and the concentration of vitamin C but they reduced the relationship TSS/TA, the coloration of the pulp and the pH. The deficiency of K reduced TSS and that of Ca and S increased it. The deficiencies of N and K reduced the sensorial acceptance of the fruits.The deficiencies of P, Mg and B did not alter the sensory properties of pineapple.

  11. Disponibilidade de macronutrientes em cultivares de cana-de-açúcar submetidas à competição com Brachiaria brizantha Macronutrients availability in sugarcane varieties grown under increasing densities of Brachiaria brizantha

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    Leandro Galon

    2012-08-01

    Full Text Available Objetivou-se com o trabalho verificar os teores foliares dos macronutrientes e o desenvolvimento das cultivares de cana-açúcar 'RB72454', 'RB867515' e 'SP801816' em competição com populações de Brachiaria brizantha. Os tratamentos utilizados foram: 1 cultivar de cana-de-açúcar 'RB72454' e população de B. brizantha de 0, 1, 3, 7, 15, 32, 40, 32, 64, 92, 88 e 112; 2 'RB867515' e 0, 1, 4, 14, 10, 18, 28, 30, 36, 54, 52 e 72; 3 'SP801816' e 0, 1, 3, 6, 14, 20, 24, 26, 26, 32, 46 e 56 plantas m-2. Aos 120 dias após a emergência da cultura, foi quantificada a massa seca (MS da parte aérea da cana-de-açúcar e da B. brizantha. Aos 290 dias após a emergência (DAE, foram coletadas amostras das folhas +3 (terceira folha a partir do ápice das plantas, nas quais foram avaliadas as concentrações de nitrogênio total, fósforo, potássio, magnésio e cálcio. Com o aumento da população de B. brizantha, observou-se redução da MS somente na cultivar 'RB72454'. O aumento na população de B. brizantha reduziu a concentração de fósforo em todas as cultivares, nitrogênio em 'RB72454' e 'SP801816', potássio e magnésio para 'RB72454'. Nas populações mais elevadas de B. brizantha, houve maior competição pelos nutrientes disponíveis no meio, sendo o fósforo o mais limitante. A cultivar 'RB72454' foi a menos competitiva pelos nutrientes no solo. As cultivares apresentaram redução média de 76% na produtividade de colmos na densidade máxima de B. brizantha.This trial aimed to verify foliar levels of macronutrients and development of sugarcane cultivars 'RB72454', 'RB867515' and 'SP801816' under competition with populations of Brachiaria brizantha. The field trial was installed where treatments were: 1 Sugarcane 'RB72454' and B. brizantha population of 0, 1, 3, 7, 15, 32, 40, 32, 64, 92, 88 e 112; 2 'RB867515' e 0, 1, 4, 14, 10, 18, 28, 30, 36, 54, 52 e 72; 3 'SP801816' e 0, 1, 3, 6, 14, 20, 24, 26, 26, 32, 46 e 56 plants m-2. At 120

  12. Macronutrient and calcium intakes of rural left-behind children living in Ziyang%资阳市农村留守儿童宏量营养素和钙摄入现况

    Institute of Scientific and Technical Information of China (English)

    郝刚; 张瑞; 张莎; 封平; 尹开武; 周欢

    2013-01-01

    目的 了解农村留守儿童营养素摄人情况以及相关影响因素,为开展营养干预、改善农村儿童营养状况提供依据.方法 分层整群抽取四川省资阳市2所农村小学二~五年级学生共计472名,使用调查问卷收集家庭构成,并采用7d连续膳食个人食物登记法收集调查对象的饮食状况.结果 非留守、双亲留守、单亲留守儿童的总能量摄入量与推荐值之比分别为0.57,0.56,0.52,总能量、脂肪、钙的摄入量差异均有统计学意义(P<0.05或P<0.01);回归分析显示,留守类别、吃零食情况是影响农村儿童总能量摄入的重要因素.结论 农村留守儿童膳食营养素中的总能量、蛋白质、脂肪、钙的摄人量均不足.应着重针对留守儿童及其吃零食行为等方面进行膳食营养干预.%Objective To investigate the macronutrient and calcium intake status and related factors among left-behind children living in rural areas.Methods By applying the stratified cluster sampling,472 children and adolescents in grade 2-5were enrolled in rural areas to complete the questionnaires about general status and nutrient intake status.Results The ratios of gross energy intake and its RNIs for no-left-behind children,left-behind children with parents,and left-behind children with single parent were 0.57,0.56 and 0.52,and variance analysis showed that the difference was statistically significant(P < 0.05),same were the fat and calcium's intake.Regression analysis showed that the main related factors were left type,the conditions of eating snacks and so on.Conclusion The nutrient intake status of rural children especially in gross energy,fat and calcium was worrying,especially for left-behind children.So the nutrition intervention should focus on left-behind children and their behavior of eating snacks.

  13. Influence factors of macronutrients and energy content of donor human milk%捐赠母乳宏量营养素和能量的影响因素

    Institute of Scientific and Technical Information of China (English)

    陈慧敏; 肖妮蓉; 刘喜红; 孙静; 吴锦晖; 萧敏华

    2016-01-01

    Objectives To explore the effect of holder pasteurization, frozen storage time and thawing methods on macronutrients and energy content of donor human milk, and to provide theoretical basis for the rational use of breast milk. Methods Thirty-three samples of donor human milk were collected and an aliquot of each sample was analyzed before and after pasteurization. The remaining milk after pasteurization was split into 9 aliquot , and frozen at -20 ℃. After 30, 60, and 90 days, the milk was thawed by three different methods of room tempe-rature, 4 ℃ refrigeration, and 37 ℃ water bath, respectively. The nutrient components of each aliquot were analyzed and compared. Results We observed a mild reduction in fat and energy content after pasteurization (P <0.05). A significant decrease of fat, protein and energy content with the prolonged storage time was observed (P <0.01), and during the whole process (pasteurization + frozen storage), the decrease of fat, protein and energy content was 36.6%, 32.6%and 22.6%, respectively. The protein was influenced mostly by different thawing methods and the content of protein reached highest while thawed at 4 ℃ refrigeration. Conclusions Holder pasteurization and frozen storage at-20℃significantly reduce fat, protein and energy content of donor human milk. The donor milk should be used as quickly as possible when applied for preterm infants and thawing at 4 ℃ refrigeration is recommended before delivery to newborn infants.%目的:探讨巴氏消毒、储存时间及解冻方式对捐赠母乳宏量营养素和能量的影响,为母乳库捐赠母乳的合理应用提供理论依据。方法:收集33例捐赠母乳样本,在巴氏消毒前后分析营养成分;将消毒后的每份样本平均分为9份,于-20℃冷冻储存30、60、90 d 时各取3份,分别用室温条件、4℃冷藏条件、37℃水浴快速解冻3种方式将母乳解冻后,测定营养成分并进行比较分析。结果:巴氏

  14. Sintomas de deficiência nutricional em mudas de Acacia holosericea em resposta à omissão de macronutrientes Symptoms of nutritional deficiency in seedlings of Acacia holosericea submitted to absence of macronutrients

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    Tathiane Santi Sarcinelli

    2004-04-01

    Full Text Available A Acacia holosericea é uma espécie leguminosa arbórea bastante utilizada na recuperação de áreas degradadas. O conhecimento dos sintomas de deficiência nutricional apresentados por esta espécie possibilita a identificação e a correção de deficiências em exemplares plantados em substratos degradados. Os objetivos deste trabalho foram caracterizar a sintomatologia visual de carências de macronutrientes e avaliar a produção de biomassa e o acúmulo de nutrientes nas raízes e na parte aérea de mudas de Acacia holosericea, submetidas a diferentes soluções nutritivas com exclusão de macronutrientes. Os tratamentos constituíram-se de sete soluções nutritivas: 1 solução completa (SC; 2 SC -N; 3 SC -P; 4 SC -K; 5 SC -Ca; 6 SC -Mg; e 7 SC -S. Os tratamentos -N e Mg foram os que mais afetaram a produção total de biomassa. O decréscimo de produção manifestou-se na seguinte ordem: -N = -Mg > -K > -S > -Ca > SC > -P. As plantas do tratamento -N formaram nódulos no sistema radicular, exibindo teores foliares de N maiores que as plantas do tratamento SC. Com exceção dos tratamentos SC e -P, todos os outros apresentaram sintomas de deficiência. A ausência de S alterou a disposição natural dos filódios novos da A. holosericea.Acacia holosericea is a leguminous species that has been extensively used in land reclamation programs. The knowledge of its nutritional symptoms allows the identification and correction of deficiencies in individuals planted in degraded substrates. The aim of this work was to characterize the behavior of seedlings of A. holosericea submitted to different nutritional solutions with absence of macronutrients. The treatments consisted of seven nutritional solutions: 1 Complete solution (SC; 2 SC - N; 3 SC -P; 4 SC -K; 5 SC -Ca; 6 SC -Mg; 7 SC -S. Treatments -N and -Mg were the ones that most affected biomass production. Decrease in biomass production occurred in the following order: -N = -Mg > -K > -S

  15. Adubação NK no desenvolvimento e na concentração de macronutrientes no florescimento do feijoeiro Nitrogen and potassium fertilization and the development and macronutrient composition during flowering of common beans

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    Eduardo do Valle Lima

    2001-03-01

    Full Text Available O nitrogênio e o potássio são os elementos mais absorvidos e exportados pelo feijoeiro, sendo a adubação mineral entre os produtores bastante variável quanto as doses aplicadas. Este trabalho avalia os efeitos de doses de N (0, 60, 80, 100 e 120 kg ha-1 e K2O (0, 60 e 120 kg ha-1 no desenvolvimento do feijoeiro, por meio do número de unidades estruturais, peso de material fresco e seco, e a concentração de macronutrientes no florescimento. O experimento foi realizado em Botucatu, SP., em túnel plástico, utilizando-se a cultivar 'Pérola'. Duas plantas foram cultivadas em vasos de 15 L, preenchidos com terra de Latossolo Vermelho Distrófico típico, textura média, por 50 dias. As doses de NK foram parceladas em cobertura aos 20 e 40 dias após semeadura. As variáveis estudadas foram influenciadas pela interação entre as doses de N e K. A adubação parcelada com N via solo, independentemente das doses utilizadas ou da fertilização com K, aumenta a produção de matéria seca sem interferir nos teores de N da parte aérea do feijoeiro, assim como os de K, Ca e Mg. A omissão de N em cobertura reduz o teor de clorofila, diminuindo a produção de matéria seca, mas não interferindo no número de flores. Os níveis de K utilizados não diminuíram os teores de Ca e Mg da planta.Nitrogen and potassium are absorbed and transported more than any other element by bean plants. Fertilizer levels vary greatly among agriculturists and, therefor our aim was to study the effect of N levels (0, 60, 80, 100, 120 kg ha-1 and K2O levels (0, 60, 120 kg ha-1 on bean development, evaluating number of flowers, fresh weight, dry weight and macronutrients during flowering. The experiment was carried out at Botucatu, SP, Brazil, in plastic tunnels, with the bean cultivar Pérola. Two plants were grown for 50 days in 15L pots filled with an Haplorthox. The NK fertilizations were parceled 20 and 40 days after sowing. The parameters were influenced by N

  16. Compactação do solo e macronutrientes primários na Brachiaria brizantha cv. Piatã e Panicum maximum cv. Mombaça Soil compaction and primary macronutrients in Brachiaria brizantha cv. Piatã e Panicum maximum cv. Mombaça

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    Carlos E. A. Cabral

    2012-04-01

    Full Text Available Os macronutrientes primários possuem papel relevante na adubação de forrageiras, em função da sua participação no custo de produção, razão pela qual se objetivou avaliar os efeitos da compactação na concentração de macronutrientes primários em folhas diagnósticas dos capins Piatã e Mombaça. O experimento foi realizado em casa de vegetação, com delineamento inteiramente casualizado, composto de oito tratamentos e três repetições, em esquema fatorial 2x4, com duas gramíneas (capim-piatã e capim-mombaça e de quatro densidades do solo (1,0; 1,2; 1,4 e 1,6 Mg m-3. Dois cortes foram realizados, o primeiro aos 42 dias após o desbaste e o segundo 46 dias após o primeiro corte. No primeiro período de crescimento das gramíneas forrageiras a compactação do solo interfere na absorção de nitrogênio e fósforo enquanto no segundo período de crescimento ocorre limitação na absorção de nitrogênio e potássio. O nitrogênio é o macronutriente primário mais limitado pela compactação do solo.The primary macronutrients have an important role in the forage fertilization, depending on their contribution to the production cost. This paper aimed to evaluate the effects of soil compaction on the concentration of primary macronutrients present in diagnostic leaves of Piatã and Mombaça grasses. The experiment was conducted in a greenhouse with a randomized statistical design, consisting of eight treatments and three replications in 2 x 4, factorial scheme, with two grases (Piatã grass and Mombaça and four soil densities (1.0, 1.2 , 1.4 and 1.6 Mg m-3. Two harvest of shoots were made, the first 42 days after the plant thinning, and the second 46 days after the first cutting. In the first growing period, the soil compaction interfere with the absorption of nitrogen and phosphorus, while in the second growing period there is a limitation in the absorption of nitrogen and potassium. Nitrogen is the primary macronutrient most

  17. Daily intake of macronutrients in a group of institutionalized elderly people in León. Spain Ingestión diaria de macronutrientes por un grupo de ancianos ingresados en residencias de León. España

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    M. T. García-Arias

    2003-04-01

    Full Text Available Monitoring of energy distribution of the three macronutrients of diet could be beneficial in order to improve the physiological status of elderly people. The objective of this study is to analyse total daily energy intake as well as the caloric contribution of the macronutrients and alcohol, which make up basic diet of five nursing homes in León (Spain. Dietary consumption was evaluated in a group of 107 elderly people, aged 65-98 years. A precise weighing method was used to conduct the control of food intake covering seven days. Protein, carbohydrates, fat, alcohol, dietary fiber and cholesterol intake were obtained. Weight, and Height also were measured. Total dietary energy intake was significantly higher in men (130.5% than in women (115.6%, with regard to recommended value. Relative contribution of macronutrients to total energy intake is extremely unbalanced. Energy derived from protein was very high (16.7%, energy derived from fat was also very high, and significantly higher for females (39.6% than for males (34.4%, whereas the proportion derived from carbohydrates was very low, although also significantly higher in females (41.5% than in males (35.8%, due to the high energy percentage that make up the alcohol intake in males (9.1%. A review of the diet offered by nursing homes, not only directed at the adjustment of total energy intake but also with respect to alcohol intake and macronutrient content of foodstuffs used in the elaboration of the menus, would be required in order not to unbalance the caloric profile of the diet.La supervisión de la distribución energética de los tres macronutrientes de la dieta podría mejorar el estado fisiológico de los ancianos. El objetivo de este estudio es analizar la ingestión energética diaria total y la contribución calórica de los macronutrientes y del alcohol, que representan la alimentación básica de cinco residencias para ancianos de León (España. Se ha examinado el consumo

  18. Combinatorial Gene Regulation Using Auto-Regulation

    Science.gov (United States)

    Hermsen, Rutger; Ursem, Bas; ten Wolde, Pieter Rein

    2010-01-01

    As many as 59% of the transcription factors in Escherichia coli regulate the transcription rate of their own genes. This suggests that auto-regulation has one or more important functions. Here, one possible function is studied. Often the transcription rate of an auto-regulator is also controlled by additional transcription factors. In these cases, the way the expression of the auto-regulator responds to changes in the concentrations of the “input” regulators (the response function) is obviously affected by the auto-regulation. We suggest that, conversely, auto-regulation may be used to optimize this response function. To test this hypothesis, we use an evolutionary algorithm and a chemical–physical model of transcription regulation to design model cis-regulatory constructs with predefined response functions. In these simulations, auto-regulation can evolve if this provides a functional benefit. When selecting for a series of elementary response functions—Boolean logic gates and linear responses—the cis-regulatory regions resulting from the simulations indeed often exploit auto-regulation. Surprisingly, the resulting constructs use auto-activation rather than auto-repression. Several design principles show up repeatedly in the simulation results. They demonstrate how auto-activation can be used to generate sharp, switch-like activation and repression circuits and how linearly decreasing response functions can be obtained. Auto-repression, on the other hand, resulted only when a high response speed or a suppression of intrinsic noise was also selected for. The results suggest that, while auto-repression may primarily be valuable to improve the dynamical properties of regulatory circuits, auto-activation is likely to evolve even when selection acts on the shape of response function only. PMID:20548950

  19. 几种海水和淡水贝类的大宗营养成分比较研究%Comparison of macronutrient components of several marine and freshwater shellfish

    Institute of Scientific and Technical Information of China (English)

    李阅兵; 孙立春; 刘承初; 李家乐

    2012-01-01

    This paper reported and compared macronutrient components of six species of marine and freshwater shellfish in China.Marine shellfish species included Crassostrea ariakensis(the Jinjiang or Asian oyster),Solen strictus(razor clam),and Paphia undulata(short-necked clam or undulated surf clam).Freshwater species were Anodonta woodiana(Chinese pond mussel,the Eastern Asiatic freshwater clam or swan-mussel),Cipangopaludina cathayensis(river snail),and Bellamya purificata(mud snail).No significant differences were found in water content of edible portions among all species except the Chinese pond mussel.However,remarkable differences were detected in contents of crude protein,lipid,and ash.Razor and short-necked clam was classified as shellfish with high protein,containing approximately 75% protein,8% lipid,and 14% ash(at dry mass),respectively.Chinese pond mussel and the Jinjiang oyster belonged to shellfish species rich in lipid(14% lipid,50% protein,and 6% ash).River and mud snails were grouped as shellfish with high ash(30% ash,60% protein,and 3% lipid).Based on amino acid scores,protein quality of these shellfish was slightly lower than whole egg protein in general.However,score of lysine was higher than that of whole egg protein,indicating that shellfish meat can exert better complementary effects of proteins if combining with food stuffs in lack of lysine especially grains and cereals.Regarding lipid quality,marine shellfish showed more advantages than freshwater species since the former contained higher poly-unsaturated fatty acids especially eicosapentaenoic acid(EPA) and docosahaenoic acid(DHA) than the latter.The total amount of EPA and DHA in razor and short-necked clams,and the Jinjiang oyster was 14.19%,25.51% and 34.29%,respectively.However,no EPA or DHA was detected in river snail.In mineral nutrients,two species of snails possessed promising potential and might be applied in development of natural dietary

  20. Macronutrientes em folhas diagnósticas do capim-tanzânia adubado com nitrogênio e cálcio Macronutrients concentrations in Tanzania guineagrass diagnostic leaves supplied with nitrogen and calcium rates

    Directory of Open Access Journals (Sweden)

    Cristiane Prezotto Silveira

    2010-04-01

    .50; 1.75; 3.00; 4.25 e 5.50 mmol L-1 resulting in 13 nitrogen:calcium combinations (mmol L-1: 2:0.50; 2:3.00; 2:5.50; 9:1.75; 9:4.25; 16:0.50; 16:3.00; 16:5.50; 23:1.75; 23:4.25; 30:0.50; 30:3.00 and 30:5.50. Macronutrient concentrations were determined in the two recently expanded leaf blades (diagnostic leaves collected in the three harvests of Tanzania guineagrass. The results showed that, in the first harvest of the plants, calcium rates did not interact with nitrogen for any of the nutritional traits, except for sulphur concentration in the diagnostic leaves. The interaction nitrogen × calcium was significant for concentrations of calcium and sulphur in the diagnostic leaves at the second and third samplings of the grass. Nitrogen rates and, not calcium rates, are determinant for nitrogen, phosphorus, and potassium concentrations in the diagnostic leaves of Tanzania guineagrass. The concentration of calcium at the first harvest of the grass depends only on the supply of this nutrient. Concentration of magnesium in plant tissue decreases as nitrogen or calcium supply increases. Reduction of calcium to 40% of that one used in the nutrient solution does not reduce nutritional parameters of this grass, even with the supply of high nitrogen rate.

  1. Global regulation of gene expression and cell differentiation in Caulobacter crescentus in response to nutrient availability.

    Science.gov (United States)

    England, Jennifer C; Perchuk, Barrett S; Laub, Michael T; Gober, James W

    2010-02-01

    In a developmental strategy designed to efficiently exploit and colonize sparse oligotrophic environments, Caulobacter crescentus cells divide asymmetrically, yielding a motile swarmer cell and a sessile stalked cell. After a relatively fixed time period under typical culture conditions, the swarmer cell differentiates into a replicative stalked cell. Since differentiation into the stalked cell type is irreversible, it is likely that environmental factors such as the availability of essential nutrients would influence the timing of the decision to abandon motility and adopt a sessile lifestyle. We measured two different parameters in nutrient-limited chemostat cultures, biomass concentration and the ratio of nonstalked to stalked cells, over a range of flow rates and found that nitrogen limitation significantly extended the swarmer cell life span. The transcriptional profiling experiments described here generate the first comprehensive picture of the global regulatory strategies used by an oligotroph when confronted with an environment where key macronutrients are sparse. The pattern of regulated gene expression in nitrogen- and carbon-limited cells shares some features in common with most copiotrophic organisms, but critical differences suggest that Caulobacter, and perhaps other oligotrophs, have evolved regulatory strategies to deal distinctly with their natural environments. We hypothesize that nitrogen limitation extends the swarmer cell lifetime by delaying the onset of a sequence of differentiation events, which when initiated by the correct combination of external environmental cues, sets the swarmer cell on a path to differentiate into a stalked cell within a fixed time period.

  2. K+ uptake in plant roots. The systems involved, their regulation and parallels in other organisms.

    Science.gov (United States)

    Nieves-Cordones, Manuel; Alemán, Fernando; Martínez, Vicente; Rubio, Francisco

    2014-05-15

    Potassium (K(+)) is an essential macronutrient for plants. It is taken into the plant by the transport systems present in the plasma membranes of root epidermal and cortical cells. The identity of these systems and their regulation is beginning to be understood and the systems of K(+) transport in the model species Arabidopsis thaliana remain far better characterized than in any other plant species. Roots can activate different K(+) uptake systems to adapt to their environment, important to a sessile organism that needs to cope with a highly variable environment. The mechanisms of K(+) acquisition in the model species A. thaliana are the best characterized at the molecular level so far. According to the current model, non-selective channels are probably the main pathways for K(+) uptake at high concentrations (>10mM), while at intermediate concentrations (1mM), the inward rectifying channel AKT1 dominates K(+) uptake. Under lower concentrations of external K(+) (100μM), AKT1 channels, together with the high-affinity K(+) uptake system HAK5 contribute to K(+) acquisition, and at extremely low concentrations (root K(+) uptake are shared by other organisms, whilst others are specific to plants. This indicates that some crucial properties of the ancestral of K(+) transport systems have been conserved through evolution while others have diverged among different kingdoms.

  3. Trout Stream Special Regulations

    Data.gov (United States)

    Minnesota Department of Natural Resources — This layer shows Minnesota trout streams that have a special regulation as described in the 2006 Minnesota Fishing Regulations. Road crossings were determined using...

  4. Sulfur nutrient availability regulates root elongation by affecting root indole-3-acetic acid levels and the stem cell niche.

    Science.gov (United States)

    Zhao, Qing; Wu, Yu; Gao, Lei; Ma, Jun; Li, Chuan-You; Xiang, Cheng-Bin

    2014-12-01

    Sulfur is an essential macronutrient for plants with numerous biological functions. However, the influence of sulfur nutrient availability on the regulation of root development remains largely unknown. Here, we report the response of Arabidopsis thaliana L. root development and growth to different levels of sulfate, demonstrating that low sulfate levels promote the primary root elongation. By using various reporter lines, we examined in vivo IAA level and distribution, cell division, and root meristem in response to different sulfate levels. Meanwhile the dynamic changes of in vivo cysteine, glutathione, and IAA levels were measured. Root cysteine, glutathione, and IAA levels are positively correlated with external sulfate levels in the physiological range, which eventually affect root system architecture. Low sulfate levels also downregulate the genes involved in auxin biosynthesis and transport, and elevate the accumulation of PLT1 and PLT2. This study suggests that sulfate level affects the primary root elongation by regulating the endogenous auxin level and root stem cell niche maintenance. © 2014 Institute of Botany, Chinese Academy of Sciences.

  5. Hepcidin: regulation of the master iron regulator

    Science.gov (United States)

    Rishi, Gautam; Wallace, Daniel F.; Subramaniam, V. Nathan

    2015-01-01

    Iron, an essential nutrient, is required for many diverse biological processes. The absence of a defined pathway to excrete excess iron makes it essential for the body to regulate the amount of iron absorbed; a deficiency could lead to iron deficiency and an excess to iron overload and associated disorders such as anaemia and haemochromatosis respectively. This regulation is mediated by the iron-regulatory hormone hepcidin. Hepcidin binds to the only known iron export protein, ferroportin (FPN), inducing its internalization and degradation, thus limiting the amount of iron released into the blood. The major factors that are implicated in hepcidin regulation include iron stores, hypoxia, inflammation and erythropoiesis. The present review summarizes our present knowledge about the molecular mechanisms and signalling pathways contributing to hepcidin regulation by these factors. PMID:26182354

  6. General Theories of Regulation

    NARCIS (Netherlands)

    Hertog, J.A. den

    1999-01-01

    This chapter makes a distinction between three types of theories of regulation: public interest theories, the Chicago theory of regulation and the public choice theories. The Chicago theory is mainly directed at the explanation of economic regulation; public interest theories and public choice theor

  7. A Natural Light/Dark Cycle Regulation of Carbon-Nitrogen Metabolism and Gene Expression in Rice Shoots.

    Science.gov (United States)

    Li, Haixing; Liang, Zhijun; Ding, Guangda; Shi, Lei; Xu, Fangsen; Cai, Hongmei

    2016-01-01

    Light and temperature are two particularly important environmental cues for plant survival. Carbon and nitrogen are two essential macronutrients required for plant growth and development, and cellular carbon and nitrogen metabolism must be tightly coordinated. In order to understand how the natural light/dark cycle regulates carbon and nitrogen metabolism in rice plants, we analyzed the photosynthesis, key carbon-nitrogen metabolites, and enzyme activities, and differentially expressed genes and miRNAs involved in the carbon and nitrogen metabolic pathway in rice shoots at the following times: 2:00, 6:00, 10:00, 14:00, 18:00, and 22:00. Our results indicated that more CO2 was fixed into carbohydrates by a high net photosynthetic rate, respiratory rate, and stomatal conductance in the daytime. Although high levels of the nitrate reductase activity, free ammonium and carbohydrates were exhibited in the daytime, the protein synthesis was not significantly facilitated by the light and temperature. In mRNA sequencing, the carbon and nitrogen metabolism-related differentially expressed genes were obtained, which could be divided into eight groups: photosynthesis, TCA cycle, sugar transport, sugar metabolism, nitrogen transport, nitrogen reduction, amino acid metabolism, and nitrogen regulation. Additionally, a total of 78,306 alternative splicing events have been identified, which primarily belong to alternative 5' donor sites, alternative 3' acceptor sites, intron retention, and exon skipping. In sRNA sequencing, four carbon and nitrogen metabolism-related miRNAs (osa-miR1440b, osa-miR2876-5p, osa-miR1877 and osa-miR5799) were determined to be regulated by natural light/dark cycle. The expression level analysis showed that the four carbon and nitrogen metabolism-related miRNAs negatively regulated their target genes. These results may provide a good strategy to study how natural light/dark cycle regulates carbon and nitrogen metabolism to ensure plant growth and

  8. TOWARD MORE EFFECTIVE REGULATION

    Energy Technology Data Exchange (ETDEWEB)

    J. GRAF

    2000-06-01

    This paper proposes a model relationship between the operator engaged in a hazardous activity, the regulator of that activity, and the general public. The roles and responsibilities of each entity are described in a way that allows effective communication flow. The role of the regulator is developed using the steam boiler as an example of a hazard subject to regulation; however, the model applies to any regulated activity. In this model the safety analyst has the extremely important role of communicating sometimes difficult technical information to the regulator in a way that the regulator can provide credible assurance to the general public as to the adequacy of the control of the hazardous activity. The conclusion asserts that acceptance of the model, understanding of the roles and responsibilities and definition of who communicates what information to whom will mitigate frustration on the part of each of the three entities.

  9. Benchmarking and Regulation

    DEFF Research Database (Denmark)

    Agrell, Per J.; Bogetoft, Peter

    nchmarking methods, and in particular Data Envelopment Analysis (DEA), have become well-established and informative tools for economic regulation. DEA is now routinely used by European regulators to set reasonable revenue caps for energy transmission and distribution system operators....... The application of benchmarking in regulation, however, requires specific steps in terms of data validation, model specification and outlier detection that are not systematically documented in open publications, leading to discussions about regulatory stability and economic feasibility of these techniques....... In this paper, we review the modern foundations for frontier-based regulation and we discuss its actual use in several jurisdictions....

  10. Reconceptualizing Civil Regulation

    DEFF Research Database (Denmark)

    Galang, Roberto Martin; Castello, Itziar

    2011-01-01

    This article re-conceptualizes the notion of civil regulation, through an analysis of 775 projects by firms located in 21 Asian countries, wherein we map the state of civil regulation initiatives in the region. We challenge two established assumptions in the Corporate Social Responsibility...... literature. First, contrary to what is commonly argued, we claim that strong states in Asia promote civil regulation in what we call the “paradox of the weak state”. Second, we not only argue that civil regulation is mainly enforced by multinational enterprises willing to promote international social...

  11. Novel regulators of spermatogenesis.

    Science.gov (United States)

    Fok, Kin Lam; Chen, Hao; Ruan, Ye Chun; Chan, Hsiao Chang

    2014-05-01

    Spermatogenesis is a multistep process that supports the production of millions of sperm daily. Understanding of the molecular mechanisms that regulate spermatogenesis has been a major focus for decades. Yet, the regulators involved in different cellular processes of spermatogenesis remain largely unknown. Human diseases that result in defective spermatogenesis have provided hints on the molecular mechanisms regulating this process. In this review, we have summarized recent findings on the function and signaling mechanisms of several genes that are known to be associated with disease or pathological processes, including CFTR, CD147, YWK-II and CT genes, and discuss their potential roles in regulating different processes of spermatogenesis.

  12. Three promoters regulate the transcriptional activity of the human holocarboxylase synthetase gene.

    Science.gov (United States)

    Xia, Mengna; Malkaram, Sridhar A; Zempleni, Janos

    2013-11-01

    Holocarboxylase synthetase (HLCS) is the only protein biotin ligase in the human proteome. HLCS-dependent biotinylation of carboxylases plays crucial roles in macronutrient metabolism. HLCS appears to be an essential part of multiprotein complexes in the chromatin that cause gene repression and contribute toward genome stability. Consistent with these essential functions, HLCS knockdown causes strong phenotypes including shortened life span and low stress resistance in Drosophila melanogaster, and de-repression of long-terminal repeats in humans, other mammalian cell lines and Drosophila. Despite previous observations that the expression of HLCS depends on biotin status in rats and in human cell lines, little is known about the regulation of HLCS expression. The goal of this study was to identify promoters that regulate the expression of the human HLCS gene. Initially, the human HLCS locus was interrogated in silico using predictors of promoters including sequences of HLCS mRNA and expressed sequence tags, CpG islands, histone marks denoting transcriptionally poised chromatin, transcription factor binding sites and DNaseI hypersensitive regions. Our predictions revealed three putative HLCS promoters, denoted P1, P2 and P3. Promoters lacked a TATA box, which is typical for housekeeping genes. When the three promoters were cloned into a luciferase reporter plasmid, reporter gene activity was at least three times background noise in human breast, colon and kidney cell lines; activities consistently followed the pattern P1>P3>P2. Promoter activity depended on the concentration of biotin in culture media, but the effect was moderate. We conclude that we have identified promoters in the human HLCS gene.

  13. Plant Growth Regulators.

    Science.gov (United States)

    Nickell, Louis G.

    1978-01-01

    Describes the effect of "plant growth regulators" on plants, such as controlling the flowering, fruit development, plant size, and increasing crop yields. Provides a list of plant growth regulators which includes their chemical, common, and trade names, as well as their different use(s). (GA)

  14. Mortgage market regulation: Europe

    NARCIS (Netherlands)

    Aalbers, M.B.; Smith, S.J.

    2012-01-01

    Despite several European Union (EU) initiatives, there is only limited pan-European mortgage market regulation. The EU strategy can be characterised as one of parallel liberalisation and consolidation. This article highlights the key differences in regulation among European mortgage markets.

  15. Regulation of SUMO Modification

    NARCIS (Netherlands)

    P.M. Knipscheer (Puck Maria)

    2007-01-01

    textabstractThe small ubiquitin related modifier SUMO is a posttranslational modifier that functions in a wide range of cellular processes like intracellular transport, cell cycle regulation, DNA repair and regulation of transcription. SUMO is an 11 kDa protein and is ligated to its target proteins

  16. Brief neonatal nutritional supplementation has sex-specific effects on glucose tolerance and insulin regulating genes in juvenile lambs.

    Science.gov (United States)

    Jaquiery, Anne L; Park, Sharon S; Phua, Hui Hui; Berry, Mary J; Meijler, Daphne; Harding, Jane E; Oliver, Mark H; Bloomfield, Frank H

    2016-12-01

    The nutritional plane and composition during fetal life can impact upon growth and epigenetic regulation of genes affecting pancreatic β-cell development and function. However, it is not clear whether β-cell development can be altered by nutritional factors or growth rate after birth. We therefore investigated the effect of neonatal nutritional supplements on growth, glucose tolerance, and pancreatic development in lambs. Newborn lambs were randomized to daily nutritional supplements, calculated to increase macronutrient intake to a similar degree as human breast milk fortifier, or an equivalent volume of water, for 2 wk while continuing to suckle ewe milk. Intravenous glucose tolerance test (IVGTT) was performed at 4 mo of age, and pancreata collected for molecular analysis. Supplemented lambs had slower weight gain than controls. In supplemented lambs, insulin response to IVGTT was increased in males but decreased in females, compared to same sex controls, and was unrelated to growth rate. mRNA expression of key genes in β-cell development showed sexually dimorphic effects. Epigenetic change occurred in the promotor region of PDX1 gene with decreased suppression and increased activation marks in supplemented lambs of both sexes. Nutritional interventions in early life have long-term, sex-specific effects on pancreatic function.

  17. Public regulators and CSR

    DEFF Research Database (Denmark)

    Buhmann, Karin

    2016-01-01

    for responsible business conduct, connecting to social expectations and bridging to public regulation. This UN guidance has had a significant bearing on how public regulators seek to influence business conduct beyond Human Rights to broader Corporate Social Responsibility (CSR) concerns. Drawing on examples...... of such public regulatory governance, this article explores and explains developments towards a juridification of CSR entailing efforts by public regulators to reach beyond jurisdictional and territorial limitations of conventional public law to address adverse effects of transnational economic activity. Through...

  18. Epigenetic Regulation of Adipokines

    Directory of Open Access Journals (Sweden)

    Tho X. Pham

    2017-08-01

    Full Text Available Adipose tissue expansion in obesity leads to changes in the expression of adipokines, adipocyte-specific hormones that can regulate whole body energy metabolism. Epigenetic regulation of gene expression is a mechanism by which cells can alter gene expression through the modifications of DNA and histones. Epigenetic mechanisms, such as DNA methylation and histone modifications, are intimately tied to energy metabolism due to their dependence on metabolic intermediates such as S-adenosylmethionine and acetyl-CoA. Altered expression of adipokines in obesity may be due to epigenetic changes. The goal of this review is to highlight current knowledge of epigenetic regulation of adipokines.

  19. Volume regulation in epithelia

    DEFF Research Database (Denmark)

    Larsen, Erik Hviid; Hoffmann, Else Kay

    2016-01-01

    function of iso-osmotic fluid transport that depends on Na+ recirculation. The causative relationship is discussed for a fluid-absorbing and a fluid-secreting epithelium of which the Na+ recirculation mechanisms have been identified. A large number of transporters and ion channels involved in cell volume...... regulation are cloned. The volume-regulated anion channel (VRAC) exhibiting specific electrophysiological characteristics seems exclusive to serve cell volume regulation. This is contrary to K+ channels as well as cotransporters and exchange mechanisms that may serve both transepithelial transport and cell...

  20. Electrical installations and regulations

    CERN Document Server

    Whitfield, J F

    1966-01-01

    Electrical Installations and Regulations focuses on the regulations that apply to electrical installations and the reasons for them. Topics covered range from electrical science to alternating and direct current supplies, as well as equipment for providing protection against excess current. Cables, wiring systems, and final subcircuits are also considered, along with earthing, discharge lighting, and testing and inspection.Comprised of 12 chapters, this book begins with an overview of electrical installation work, traits of a good electrician, and the regulations governing installations. The r

  1. Sport Fishing Regulations

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The regulations for sport fishing on St. Vincent National Wildlife Refuge are outlined in this document. Fishing is only permitted from sunrise to sunset, and only...

  2. Focus on PTEN regulation

    Directory of Open Access Journals (Sweden)

    Miriam eBermudez-Brito

    2015-07-01

    Full Text Available The role of PTEN as a tumour suppressor has been for a long time attributed to its lipid phosphatase activity against PI(3,4,5P3, the phospholipid product of the class I PI3Ks. Besides its traditional role as a lipid phosphatase at the plasma membrane, a wealth of data has shown that PTEN can function independently of its phosphatase activity and that PTEN also exists and plays a role in the nucleus, in cytoplasmic organelles and extracellularly. Accumulating evidence has shed light on diverse physiological functions of PTEN which are accompanied by a complex regulation of its expression and activity. PTEN levels and function are regulated transcriptionally, post-transcriptionally and post-translationally. PTEN is also sensitive to regulation by its interacting proteins and its localization. Herein, we summarize the current knowledge on mechanisms that regulate the expression and enzymatic activity of PTEN and its role in human diseases.

  3. Volume Regulated Channels

    DEFF Research Database (Denmark)

    Klausen, Thomas Kjær

    - serves a multitude of functions in the mammalian cell, regulating the membrane potential (Em), cell volume, protein activity and the driving force for facilitated transporters giving Cl- and Cl- channels a major potential of regulating cellular function. These functions include control of the cell cycle...... of volume perturbations evolution have developed system of channels and transporters to tightly control volume homeostasis. In the past decades evidence has been mounting, that the importance of these volume regulated channels and transporters are not restricted to the defense of cellular volume......, controlled cell death and cellular migration. Volume regulatory mechanisms has long been in focus for regulating cellular proliferation and my thesis work have been focusing on the role of Cl- channels in proliferation with specific emphasis on ICl, swell. Pharmacological blockage of the ubiquitously...

  4. Regulation of cholesterol homeostasis

    NARCIS (Netherlands)

    van der Wulp, Mariette Y. M.; Verkade, Henkjan J.; Groen, Albert K.

    2013-01-01

    Hypercholesterolemia is an important risk factor for cardiovascular disease. It is caused by a disturbed balance between cholesterol secretion into the blood versus uptake. The pathways involved are regulated via a complex interplay of enzymes, transport proteins, transcription factors and

  5. Regulation and controlled synchronization

    NARCIS (Netherlands)

    Huijberts, H.J.C.; Huijberts, H.J.C.; Nijmeijer, Henk; Willems, R.M.A.

    1998-01-01

    We investigate the problem of controlled synchronization as a regulator problem. In controlled synchronization one is given autonomous transmitter dynamics and controlled receiver dynamics. The question is to find a (output) feedback controller that achieves matching between transmitter and

  6. Worldwide regulations for mycotoxins.

    Science.gov (United States)

    van Egmond, Hans P

    2002-01-01

    Since the discovery of the aflatoxins in the 1960s, regulations have been established in many countries to protect the consumer from the harmful effects of mycotoxins that may contaminate foodstuffs. Various factors play a role in the decision-making process of setting limits for mycotoxins. These include scientific factors such as the availability of toxicological data, survey data, knowledge about the distribution of mycotoxins in commodities, and analytical methodology. Economical and political factors such as commercial interests and sufficiency of food supply have their impact as well. International enquiry's on existing mycotoxin legislation in foodstuffs and animal feedstuffs have been carried out several times in the 1980s and 1990s and details about tolerances, legal basis, responsible authorities, official protocols of analysis and sampling have been published. Recently a comprehensive update on worldwide regulations was published as FAO Food and Nutrition Paper 64. It appeared that at least 77 countries now have specific regulations for mycotoxins, 13 countries are known to have no specific regulations, whereas no data are available for about 50 countries, many of them in Africa. Over the years, a large diversity in tolerance levels for mycotoxins has remained. Some free trade zones (EU, MERCOSUR) are in the process of harmonizing the limits and regulations for mycotoxins in their respective member states, but it is not likely that worldwide harmonized limits for mycotoxins will soon be within reach.

  7. To regulate or not to regulate?

    Energy Technology Data Exchange (ETDEWEB)

    Mason, G.; Wrixon, A. [IAEA, Vienna (Austria)

    2006-07-01

    Full text of publication follows: In Hamlet famous soliloquy to be or not to be, he wrestles with the perennial human problem of choosing the right course of action in difficult circumstances. In recent years, we have witnessed a cast of thousands playing out a long-running scene that seems to echo Hamlet dilemma on a rather more prosaic level. When is it necessary to apply regulations to the control of exposure to ionizing radiation and when is regulatory control not warranted? This seemingly straightforward question has brought out the philosopher, ethician, lawyer, pragmatist, orator in simple radiation protection folk and has led to passionate debate on numerous occasions. This paper attempts an answer based on a review of recent developments. For deciding when to apply regulatory controls, several concepts have evolved over time, including exemption of practices and sources, exclusion of exposures and clearance of materials. These have different origins, purposes and characteristics. Exemption and clearance have often been associated with triviality of risk, while exclusion has been related to un-amenability of control. For each concept, criteria have been developed to assist the regulator in reaching a decision, but there has much disputation over numerical values. This paper briefly reviews and analyses recent developments and attempts to clarify the problem from first principles. The conclusion is that the underlying issue in each case is to determine when regulatory controls become unwarranted: that is, when the societal resources expended in applying them and complying with them would be disproportionate to any benefit they might bring. This is a natural extension of the principle of optimization of protection to the regulatory control of protection, in the context of exposure to radiation at very low levels. It also reflects common expectations of good governance: wise management of finite societal resources and avoidance of unwarranted controls on

  8. Collaborative Tax Regulation

    DEFF Research Database (Denmark)

    Boll, Karen

    2016-01-01

    their customer bases decline to commercially non-viable levels. The analysis is framed by public governance literature and argues that the regulation is an example of collaborative or interactive governance, because the tax administrators do not regulate non-compliance directly, but activate external...... stakeholders, i.e. the consumers, in the regulatory craft. The study is based on a qualitative methodology and draws on a unique case of regulation in the cleaning sector. This sector is at high risk of tax evasion and human exploitation of vulnerable workers operating in the informal economy. The article has...... implications for how tax practitioners think about collaborative and interactive regulatory initiatives. While the tax administration in the study sees the approach as effective, the analysis shows that there are a number of caveats in relation to regularity, public listing, costs and revenue focus...

  9. Staff rules and regulations

    CERN Multimedia

    HR Department

    2007-01-01

    The 11th edition of the Staff Rules and Regulations, dated 1 January 2007, adopted by the Council and the Finance Committee in December 2006, is currently being distributed to departmental secretariats. The Staff Rules and Regulations, together with a summary of the main modifications made, will be available, as from next week, on the Human Resources Department's intranet site: http://cern.ch/hr-web/internal/admin_services/rules/default.asp The main changes made to the Staff Rules and Regulations stem from the five-yearly review of employment conditions of members of the personnel. The changes notably relate to: the categories of members of the personnel (e.g. removal of the local staff category); the careers structure and the merit recognition system; the non-residence, installation and re-installation allowances; the definition of family, family allowances and family-related leave; recognition of partnerships; education fees. The administrative circulars, some of which are being revised following the ...

  10. Collaborative Tax Regulation

    DEFF Research Database (Denmark)

    Boll, Karen

    2016-01-01

    This article shows a new form of regulation within a tax administration where tax administrators abate tax evasion by nudging and motivating consumers to only purchase services from tax compliant businesses. This indirectly closes or forces tax evading businesses to change their practices, because...... their customer bases decline to commercially non-viable levels. The analysis is framed by public governance literature and argues that the regulation is an example of collaborative or interactive governance, because the tax administrators do not regulate non-compliance directly, but activate external...... implications for how tax practitioners think about collaborative and interactive regulatory initiatives. While the tax administration in the study sees the approach as effective, the analysis shows that there are a number of caveats in relation to regularity, public listing, costs and revenue focus...

  11. Volume Regulated Channels

    DEFF Research Database (Denmark)

    Klausen, Thomas Kjær

    of volume perturbations evolution have developed system of channels and transporters to tightly control volume homeostasis. In the past decades evidence has been mounting, that the importance of these volume regulated channels and transporters are not restricted to the defense of cellular volume...... but are also essential for a number of physiological processes such as proliferation, controlled cell death, migration and endocrinology. The thesis have been focusing on two Channels, namely the swelling activated Cl- channel (ICl, swell) and the transient receptor potential Vanilloid (TRPV4) channel. I: Cl......- serves a multitude of functions in the mammalian cell, regulating the membrane potential (Em), cell volume, protein activity and the driving force for facilitated transporters giving Cl- and Cl- channels a major potential of regulating cellular function. These functions include control of the cell cycle...

  12. The Impact of Regulating Social Science Research with Biomedical Regulations

    Science.gov (United States)

    Durosinmi, Brenda Braxton

    2011-01-01

    The Impact of Regulating Social Science Research with Biomedical Regulations Since 1974 Federal regulations have governed the use of human subjects in biomedical and social science research. The regulations are known as the Federal Policy for the Protection of Human Subjects, and often referred to as the "Common Rule" because 18 Federal…

  13. Other-Regulation in Collaborative Groups: Implications for Regulation Quality

    Science.gov (United States)

    Rogat, Toni Kempler; Adams-Wiggins, Karlyn R.

    2014-01-01

    The current study examines variation in other-regulation, conceptualized as efforts by one student to regulate their group's work. This study extends research which has conceptualized other-regulation as temporarily guiding others' conceptual understanding and skill development by broadening the spectrum of other-regulation to include…

  14. The Impact of Regulating Social Science Research with Biomedical Regulations

    Science.gov (United States)

    Durosinmi, Brenda Braxton

    2011-01-01

    The Impact of Regulating Social Science Research with Biomedical Regulations Since 1974 Federal regulations have governed the use of human subjects in biomedical and social science research. The regulations are known as the Federal Policy for the Protection of Human Subjects, and often referred to as the "Common Rule" because 18 Federal…

  15. Nuclear regulation and safety

    Energy Technology Data Exchange (ETDEWEB)

    Hendrie, J.M.

    1982-01-01

    Nuclear regulation and safety are discussed from the standpoint of a hypothetical country that is in the process of introducing a nuclear power industry and setting up a regulatory system. The national policy is assumed to be in favor of nuclear power. The regulators will have responsibility for economic, reliable electric production as well as for safety. Reactor safety is divided into three parts: shut it down, keep it covered, take out the afterheat. Emergency plans also have to be provided. Ways of keeping the core covered with water are discussed. (DLC)

  16. Cyberplagiarism in University Regulations

    Directory of Open Access Journals (Sweden)

    Santiago Cavanillas

    2008-12-01

    Full Text Available The article examines the legal framework for plagiarism, and its twofold nature of illicit appropriation (from the author of the plagiarized work and fraud (with regard to the target audience of the plagiarism. Based on these premises, academic cyberplagiarism is analysed as a form of plagiarism carried out using electronic tools in the university setting. The question of responsibility (who can regulate the legal consequences of plagiarism? before and after the Ley Orgánica de Universidades (organic law on universities, LOU is studied, as is the disciplinary handling of cyberplagiarism with the limited regulations currently in place at universities.

  17. Deficiência de macronutrientes em estévia: sintomas visuais e efeitos no crescimento, composição química e produção de esteviosídeo Macronutrient deficiencies in stevia: visual symptoms and effects on growth, chemical composition, and stevioside production

    Directory of Open Access Journals (Sweden)

    Marley Marico Utumi

    1999-06-01

    Full Text Available Conduziu-se experimento objetivando descrever sintomas visuais de deficiências de macronutrientes em estévia (Stevia rebaudiana e avaliar seus efeitos no crescimento, composição química e produção de esteviosídeo. Os sintomas foram: clorose generalizada, com -N; folhas verde-escuras, com -P; folhas com clorose, bronzeamento e necrose, com -K; necrose de ápices, com -Ca; clorose e necrose foliar, em "V" invertido, com -Mg e folhas verde-pálidas e menores, com -S. As deficiências de N, K e Mg reduziram o crescimento das folhas e a parte comercializável da planta, enquanto que a deficiência de Mg promoveu acentuada redução no desenvolvimento do sistema radicular. As deficiências de N, P, K e S diminuíram a relação entre matéria seca da parte aérea e das raízes, enquanto a deficiência de Mg aumentou-a. Todas as deficiências causaram a diminuição na absorção de macronutrientes, exceto a de Ca, que reduziu somente a absorção de Ca, e a de K, que não alterou as absorções de Mg e S. A composição química dos cinco últimos pares de folhas totalmente expandidas representou bem o estado nutricional da planta. As deficiências de K, Ca e S reduziram somente o teor de esteviosídeo, enquanto todas as deficiências, exceto a de P, diminuíram o conteúdo de esteviosídeo.This experiment was carried out to describe visual symptoms of macronutrients deficiencies in Stevia rebaudiana, and the effects of these deficiencies on growth, chemical composition and stevioside production. The symptoms were: yellowing with -N; dark green leaves with -P; clorotic, mottled, and necrotic leaves, with -K; apical necrosis, with -Ca; leaves with clorosis and necrosis in inverted "V" shape, with -Mg, and small pale green leaves, with -S. N, K, and Mg deficiencies reduced the leaf growth, therefore the plant marketable part. Mg deficiency caused greater reduction on the development of the radicular system. N, P, K, and S deficiencies decreasead

  18. Aquisição de açúcar e perfil de macronutrientes na cesta de alimentos adquirida pelas famílias brasileiras (2002-2003 Sugar and overall macronutrient profile in the Brazilian family diet (2002-2003

    Directory of Open Access Journals (Sweden)

    Renata Bertazzi Levy

    2010-03-01

    Full Text Available Avaliou-se a influência exercida pela aquisição de calorias de açúcar sobre a participação calórica dos demais macronutrientes da dieta. As estimativas deste estudo são baseadas em dados da Pesquisa de Orçamentos Familiares realizada no Brasil pelo Instituto Brasileiro de Geografia e Estatística entre julho de 2002 e junho de 2003. Modelos de regressão linear múltiplos foram utilizados para estudar a influência das calorias de açúcar sobre a participação calórica de cada um dos macronutrientes na aquisição domiciliar de alimentos com o controle do valor calórico total da aquisição de alimentos e variáveis sócio-demográficas. Cada caloria adquirida de açúcar eleva em 0,3 caloria a participação de gorduras na aquisição domiciliar de alimentos e diminui em 0,07 a participação de proteínas. Cada caloria de açúcar procedente de alimentos processados aumenta em 1,6 caloria a participação de gorduras e em 0,4 caloria de ácidos graxos saturados e diminui em 0,8 caloria a participação de outros carboidratos que não o açúcar. Os resultados encontrados trazem novas evidências sobre o papel prejudicial do açúcar à saúde humana.This study evaluated the impact of calories from sugar on the calorie share of other macronutrients in the Brazilian family diet. The study's estimates are based on data from the Household Budget Survey conducted by the Brazilian Institute of Geography and Statistics from July 2002 to June 2003. Multiple linear regression models were used to study the impact of sugar calories on each of the macronutrients in household food acquisition, controlling for total energy content in food acquisition and socio-demographic variables. Each calorie from sugar purchases increases the share of calories from fat by 0.3 calories and decreases the share of calories from protein by 0.7 calories. Each calorie of sugar from processed foods increases the share from fat by 1.6 calories and the share from

  19. Efeito da omissão de macronutrientes e boro no crescimento, nos sintomas de deficiências nutricionais e na composição mineral de plantas de camucamuzeiro Effect of omission of macronutrient and boron on growth, on symptoms of nutritional deficiency and mineral composition in camucamuzeiro plants (Myrciaria dubia

    Directory of Open Access Journals (Sweden)

    Ismael de Jesus Matos Viégas

    2004-08-01

    Full Text Available Com o objetivo de avaliar o efeito da omissão de macronutrientes e do micronutriente boro no crescimento, nos sintomas de deficiências nutricionais e na composição mineral em plantas de camucamuzeiro, conduziu-se experimento em casa de vegetação, mediante a técnica do elemento faltante. O delineamento experimental foi o inteiramente casualizado, com quatro repetições e oito tratamentos, sendo completo (N, P, K, Ca, Mg, S e micronutrientes e omissão individual de N, P, K, Ca, Mg, S e B. Os sintomas visuais de deficiências foram, de modo geral, de fácil caracterização para todos os nutrientes. Com exceção do fósforo, as omissões dos demais nutrientes afetaram a produção de matéria seca, quando comparados ao tratamento completo. Com base nos teores em g kg-1, dos macronutrientes, e em mg kg-1, do micronutriente boro nas folhas, infere-se em uma primeira aproximação dos valores adequados (completo, ou seja: 16,9 a 18,2 de N ; 1,2 a 1,9 de P; 5,2 a 6,0 de K; 9,9 a 11,7 de Ca; 1,4 a 3,6 de Mg; 2,4 a 2,8 de S ; 8,4 a 9,5 de B e do deficiente (omissão , 6,5 a 7,9 de N ; =0,9 de P; =1,7 de K ; 5,4 a 6,5 de Ca; =0,7 de Mg; 0,7 a 1,2 de S e 1,1 a 1,9 de BThe effects of omission of macronutrient and boron on growth, on symptoms of nutritional deficiency and mineral composition of plants of "camucamuzeiro" were evaluated. The experiment was carried out in a greenhouse, by means of the missing element technique. The experimental design was completely randomized, with eight treatments and four repetitions, including complete (N, P, K, Ca, Mg, S and micronutrients and individual omission of N, P, K, Ca, Mg, S and B. The visual symptoms of deficiency were easily characterized for all the nutrients. Excepting for P, dry mass was affected by the omission of all the other nutrients, when compared with the complete treatment. Based on the macronutrient (g kg-1 and on the micronutrient boron (mg kg-1 on leaves contents, a first approach of the

  20. Design of dual pressure regulator

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dong Soo; Kim, Kang Dae; Kim, Myoung Sub [Korea Institute of Machinery and Materials, Daejeon (Korea, Republic of)

    2008-07-01

    In this paper, we designed sandwich type pressure regulator for air pressure control system. As a result of research, we obtained several important conclusions. First, we decided theory of poppet valve and relief valve which are used in sandwich type pressure regulator, and then designed prototype of pressure regulator. Second, we organized circuit diagram of dual pressure regulator of air pressure control system.

  1. Markets, religion, regulation

    DEFF Research Database (Denmark)

    Fischer, Johan

    2016-01-01

    of regulation, certification and standardization on a global scale. Building on research on global kosher (a Hebrew term meaning “fit” or “proper”), halal (an Arabic word that literally means “permissible” or “lawful”) and Hindu vegetarianism this paper argues that these economies or markets to a large extent...

  2. Vehicle recycling regulations

    DEFF Research Database (Denmark)

    Smink, Carla

    2007-01-01

    The number of end-of-life vehicles (ELVs) in the EU is increasing continously. Around 75 percent of an ELV are recyclable metals. The forecast growth in the number of ELVs calls for regulation that aims to minimise the environmental impact of a car. Using Denmark as an example, this article...

  3. Situated bio-regulation

    DEFF Research Database (Denmark)

    Prainsack, Barbara; Wahlberg, Ayo

    2013-01-01

    Several years ago, both authors engaged in research into bioscience and biomedical regulation in Asian countries. One of us (BP) explored why the regulatory and discursive embedding of human embryonic stem cell in Israel was much more permissive than elsewhere. The other author (AW) sought to und...

  4. Regulated Gene Therapy.

    Science.gov (United States)

    Breger, Ludivine; Wettergren, Erika Elgstrand; Quintino, Luis; Lundberg, Cecilia

    2016-01-01

    Gene therapy represents a promising approach for the treatment of monogenic and multifactorial neurological disorders. It can be used to replace a missing gene and mutated gene or downregulate a causal gene. Despite the versatility of gene therapy, one of the main limitations lies in the irreversibility of the process: once delivered to target cells, the gene of interest is constitutively expressed and cannot be removed. Therefore, efficient, safe and long-term gene modification requires a system allowing fine control of transgene expression.Different systems have been developed over the past decades to regulate transgene expression after in vivo delivery, either at transcriptional or post-translational levels. The purpose of this chapter is to give an overview on current regulatory system used in the context of gene therapy for neurological disorders. Systems using external regulation of transgenes using antibiotics are commonly used to control either gene expression using tetracycline-controlled transcription or protein levels using destabilizing domain technology. Alternatively, specific promoters of genes that are regulated by disease mechanisms, increasing expression as the disease progresses or decreasing expression as disease regresses, are also examined. Overall, this chapter discusses advantages and drawbacks of current molecular methods for regulated gene therapy in the central nervous system.

  5. Federal Gasoline Regulations

    Science.gov (United States)

    The Clean Air Act requires EPA to regulate fuels and fuel additives for use in mobile sources if such fuel, fuel additive or any emission products causes or contributes to air or water pollution that may endanger the public health or welfare.

  6. Situated bio-regulation

    DEFF Research Database (Denmark)

    Prainsack, Barbara; Wahlberg, Ayo

    2013-01-01

    Several years ago, both authors engaged in research into bioscience and biomedical regulation in Asian countries. One of us (BP) explored why the regulatory and discursive embedding of human embryonic stem cell in Israel was much more permissive than elsewhere. The other author (AW) sought to und...

  7. Legislation and regulation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-09-01

    This document presents the fulfilling of the Brazilian obligations under the Convention on Nuclear Safety. The Chapter 3 of the document contains some details about the Brazilian legislation and regulation, the legislative and regulatory framework, regulatory body and responsibility of the license holder.

  8. Regulation of cholesterol homeostasis

    NARCIS (Netherlands)

    van der Wulp, Mariette Y. M.; Verkade, Henkjan J.; Groen, Albert K.

    2013-01-01

    Hypercholesterolemia is an important risk factor for cardiovascular disease. It is caused by a disturbed balance between cholesterol secretion into the blood versus uptake. The pathways involved are regulated via a complex interplay of enzymes, transport proteins, transcription factors and non-codin

  9. Regulating groundwater use

    NARCIS (Netherlands)

    Hoogesteger van Dijk, Jaime; Wester, Flip

    2017-01-01

    Around the world it has proven very difficult to develop policies and interventions that ensure socio-environmentally sustainable groundwater use and exploitation. In the state of Guanajuato, Central Mexico, both the national government and the decentralized state government have pursued to regulate

  10. Regulating the private security industry

    CERN Document Server

    Percy, Sarah

    2002-01-01

    The under-regulation of the private security industry has increasingly become a topic of media and academic interest. This Adelphi Paper enters the debate by explaining why the industry requires further regulation, and what is wrong with the current system. It begins by briefly defining the industry and explaining the need for more effective regulation, before analysing three types of regulation: domestic, international and informal (including self-regulation).

  11. Dimensionally regulated pentagon integrals

    CERN Document Server

    Bern, Z; Kosower, D A

    1994-01-01

    We present methods for evaluating the Feynman parameter integrals associated with the pentagon diagram in 4-2 epsilon dimensions, along with explicit results for the integrals with all masses vanishing or with one non-vanishing external mass. The scalar pentagon integral can be expressed as a linear combination of box integrals, up to O(epsilon) corrections, a result which is the dimensionally-regulated version of a D=4 result of Melrose, and of van Neerven and Vermaseren. We obtain and solve differential equations for various dimensionally-regulated box integrals with massless internal lines, which appear in one-loop n-point calculations in QCD. We give a procedure for constructing the tensor pentagon integrals needed in gauge theory, again through O(epsilon^0).

  12. Probiotics and Appetite Regulation

    DEFF Research Database (Denmark)

    Bjerg, Anne Toksvig

    resistance and blood lipid profile among others. Probiotics which are health promoting bacteria can potentially be used to affect the GM and thereby change metabolic outcomes of the host. Animal studies have shown associations between intake of probiotics and appetite regulation, but currently no human...... studies have investigated this effect. Supplementation with different probiotic strains have been shown to have an effect on blood lipid profiles in both animals and humans and the mechanisms behind have been studied in vitro and in rodents. The aim of the present thesis was to examine in an ex vivo...... intestine, in an animal study and in two human studies the effect of the probiotic bacteria Lactobacillus paracasei subsp. paracasei L. casei W8 (W8) on appetite regulation, blood lipids and blood fatty acids. In addition, it was investigated if W8 had an effect on the fecal microbiota of the human...

  13. Regulation of Meiotic Recombination

    Energy Technology Data Exchange (ETDEWEB)

    Gregory p. Copenhaver

    2011-11-09

    Meiotic recombination results in the heritable rearrangement of DNA, primarily through reciprocal exchange between homologous chromosome or gene conversion. In plants these events are critical for ensuring proper chromosome segregation, facilitating DNA repair and providing a basis for genetic diversity. Understanding this fundamental biological mechanism will directly facilitate trait mapping, conventional plant breeding, and development of genetic engineering techniques that will help support the responsible production and conversion of renewable resources for fuels, chemicals, and the conservation of energy (1-3). Substantial progress has been made in understanding the basal recombination machinery, much of which is conserved in organisms as diverse as yeast, plants and mammals (4, 5). Significantly less is known about the factors that regulate how often and where that basal machinery acts on higher eukaryotic chromosomes. One important mechanism for regulating the frequency and distribution of meiotic recombination is crossover interference - or the ability of one recombination event to influence nearby events. The MUS81 gene is thought to play an important role in regulating the influence of interference on crossing over. The immediate goals of this project are to use reverse genetics to identify mutants in two putative MUS81 homologs in the model plant Arabidopsis thaliana, characterize those mutants and initiate a novel forward genetic screen for additional regulators of meiotic recombination. The long-term goal of the project is to understand how meiotic recombination is regulated in higher eukaryotes with an emphasis on the molecular basis of crossover interference. The ability to monitor recombination in all four meiotic products (tetrad analysis) has been a powerful tool in the arsenal of yeast geneticists. Previously, the qrt mutant of Arabidopsis, which causes the four pollen products of male meiosis to remain attached, was developed as a facile system

  14. CNS regulation of appetite.

    Science.gov (United States)

    Harrold, Joanne A; Dovey, Terry M; Blundell, John E; Halford, Jason C G

    2012-07-01

    This article reviews the regulation of appetite from a biopsychological perspective. It considers psychological experiences and peripheral nutritional systems (both episodic and tonic) and addresses their relationship with the CNS networks that process and integrate their input. Whilst such regulatory aspects of obesity focus on homeostatic control mechanisms, in the modern environment hedonic aspects of appetite are also critical. Enhanced knowledge of the complexity of appetite regulation and the mechanisms that sustain obesity indicate the challenge presented by management of the obesity epidemic. Nonetheless, effective control of appetite expression remains a critical therapeutic target for weight management. Currently, strategies which utilise a combination of agents to target both homeostatic and hedonic control mechanisms represent the most promising approaches. This article is part of a Special Issue entitled 'Central Control of Food Intake'. Copyright © 2012 Elsevier Ltd. All rights reserved.

  15. Hormonal Regulators of Appetite

    OpenAIRE

    Austin Juliana; Marks Daniel

    2008-01-01

    Obesity is a significant cause of morbidity and mortality worldwide. There has been a significant worsening of the obesity epidemic mainly due to alterations in dietary intake and energy expenditure. Alternatively, cachexia, or pathologic weight loss, is a significant problem for individuals with chronic disease. Despite their obvious differences, both processes involve hormones that regulate appetite. These hormones act on specific centers in the brain that affect the sensations of hunger a...

  16. The regulation of hunting

    DEFF Research Database (Denmark)

    Abildtrup, Jens; Jensen, Frank

    2014-01-01

    This paper examines a tax/subsidy on hunters based on game population. The tax/subsidy is the difference between actual and optimal population multiplied by an individual, variable tax rate. The tax rate is, among other things, based on the difference between the marginal value of the game...... population to the hunter and the regulator and differences in user costs of the population. The paper shows that the population tax/subsidy secures a first-best optimum....

  17. Computing Borel's Regulator II

    CERN Document Server

    Choo, Zacky; Sánchez-García, Rubén J; Snaith, Victor P

    2009-01-01

    In our earlier article we described a power series formula for the Borel regulator evaluated on the odd-dimensional homology of the general linear group of a number field and, concentrating on dimension three for simplicity, described a computer algorithm which calculates the value to any chosen degree of accuracy. In this sequel we give an algorithm for the construction of the input homology classes and describe the results of one cyclotomic field computation.

  18. [Sleep: regulation and phenomenology].

    Science.gov (United States)

    Vecchierini, M-F

    2013-12-01

    This article describes the two-process model of sleep regulation. The 24-hour sleep-wake cycle is regulated by a homeostatic process and an endogenous, 2 oscillators, circadian process, under the influence of external synchronisers. These two processes are partially independent but influence each other, as shown in the two-sleep-process auto-regulation model. A reciprocal inhibition model of two interconnected neuronal groups, "SP on" and "SP off", explains the regular recurrence of paradoxical sleep. Sleep studies have primarily depended on observation of the subject and have determined the optimal conditions for sleep (position, external conditions, sleep duration and need) and have studied the consequences of sleep deprivation or modifications of sleep schedules. Then, electrophysiological recordings permitted the classification of sleep stages according to the observed EEG patterns. The course of a night's sleep is reported on a "hypnogram". The adult subject falls asleep in non-REM sleep (N1), then sleep deepens progressively to stages N2 and N3 with the appearance of spindles and slow waves (N2). Slow waves become more numerous in stage N3. Every 90minutes REM sleep recurs, with muscle atonia and rapid eye movements. These adult sleep patterns develop progressively during the 2 first years of life as total sleep duration decreases, with the reduction of diurnal sleep and of REM sleep. Around 2 to 4 months, spindles and K complexes appear on the EEG, with the differentiation of light and deep sleep with, however, a predominance of slow wave sleep.

  19. Staff rules and regulations

    CERN Document Server

    HR Department

    2007-01-01

    The 11th edition of the Staff Rules and Regulations, dated 1 January 2007, adopted by the Council and the Finance Committee in December 2006, is currently being distributed to departmental secretariats. The Staff Rules and Regulations, together with a summary of the main modifications made, will be available, as from next week, on the Human Resources Department's intranet site: http://cern.ch/hr-web/internal/admin_services/rules/default.asp The main changes made to the Staff Rules and Regulations stem from the five-yearly review of employment conditions of members of the personnel. The changes notably relate to: the categories of members of the personnel (e.g. removal of the local staff category); the careers structure and the merit recognition system; the non-residence, installation and re-installation allowances; the definition of family, family allowances and family-related leave; recognition of partnerships; education fees. The administrative circulars, some of which are being revised following the m...

  20. Improving CS regulations.

    Energy Technology Data Exchange (ETDEWEB)

    Nesse, R.J.; Scheer, R.M.; Marasco, A.L.; Furey, R.

    1980-10-01

    President Carter issued Executive Order 12044 (3/28/78) that required all Federal agencies to distinguish between significant and insignificant regulations, and to determine whether a regulation will result in major impacts. This study gathered information on the impact of the order and the guidelines on the Office of Conservation and Solar Energy (CS) regulatory practices, investigated problems encountered by the CS staff when implementing the order and guidelines, and recommended solutions to resolve these problems. Major tasks accomplished and discussed are: (1) legislation, Executive Orders, and DOE Memoranda concerning Federal administrative procedures relevant to the development and analysis of regulations within CS reviewed; (2) relevant DOE Orders and Memoranda analyzed and key DOE and CS staff interviewed in order to accurately describe the current CS regulatory process; (3) DOE staff from the Office of the General Counsel, the Office of Policy and Evaluation, the Office of the Environment, and the Office of the Secretary interviewed to explore issues and problems encountered with current CS regulatory practices; (4) the regulatory processes at five other Federal agencies reviewed in order to see how other agencies have approached the regulatory process, dealt with specific regulatory problems, and responded to the Executive Order; and (5) based on the results of the preceding four tasks, recommendations for potential solutions to the CS regulatory problems developed. (MCW)

  1. Ant larvae regulate worker foraging behavior and ovarian activity in a dose-dependent manner.

    Science.gov (United States)

    Ulrich, Yuko; Burns, Dominic; Libbrecht, Romain; Kronauer, Daniel J C

    2016-07-01

    Division of labor in insect societies relies on simple behavioral rules, whereby individual colony members respond to dynamic signals indicating the need for certain tasks to be performed. This in turn gives rise to colony-level phenotypes. However, empirical studies quantifying colony-level signal-response dynamics are lacking. Here, we make use of the unusual biology and experimental amenability of the queenless clonal raider ant Cerapachys biroi, to jointly quantify the behavioral and physiological responses of workers to a social signal emitted by larvae. Using automated behavioral quantification and oocyte size measurements in colonies of different sizes and with different worker to larvae ratios, we show that the workers in a colony respond to larvae by increasing foraging activity and inhibiting ovarian activation in a progressive manner, and that these responses are stronger in smaller colonies. This work adds to our knowledge of the processes that link plastic individual behavioral/physiological responses to colony-level phenotypes in social insect colonies.

  2. Iron Regulation of Pancreatic Beta-Cell Functions and Oxidative Stress

    DEFF Research Database (Denmark)

    Backe, Marie Balslev; Moen, Ingrid Wahl; Ellervik, Christina

    2016-01-01

    Dietary advice is the cornerstone in first-line treatment of metabolic diseases. Nutritional interventions directed at these clinical conditions mainly aim to (a) improve insulin resistance by reducing energy-dense macronutrient intake to obtain weight loss and (b) reduce fluctuations in insulin ...

  3. StMYB44 negatively regulates phosphate transport by suppressing expression of PHOSPHATE1 in potato

    Science.gov (United States)

    Phosphorus is an important macronutrient for plant growth, but often deficient in soil. To understand the molecular basis of the complex responses of potato (Solanum tuberosum L.) to phosphate (Pi) deficiency stress, the RNA-Seq approach was taken to identify genes responding to Pi starvation in pot...

  4. A natural light/dark cycle regulation of carbon-nitrogen metabolism and gene expression in rice shoots

    Directory of Open Access Journals (Sweden)

    Haixing Li

    2016-08-01

    Full Text Available Light and temperature are two particularly important environmental cues for plant survival. Carbon and nitrogen are two essential macronutrients required for plant growth and development, and cellular carbon and nitrogen metabolism must be tightly coordinated. In order to understand how the natural light/dark cycle regulates carbon and nitrogen metabolism in rice plants, we analyzed the photosynthesis, key carbon-nitrogen metabolites and enzyme activities, and differentially expressed genes and miRNAs involved in the carbon and nitrogen metabolic pathway in rice shoots at the following times: 2:00, 6:00, 10:00, 14:00, 18:00 and 22:00. Our results indicated that more CO2 was fixed into carbohydrates by a high net photosynthetic rate, respiratory rate and stomatal conductance in the daytime. Although high levels of the nitrate reductase activity, free ammonium and carbohydrates were exhibited in the daytime, the protein synthesis was not significantly facilitated by the light and temperature. In mRNA sequencing, the carbon and nitrogen metabolism-related differentially expressed genes were obtained, which could be divided into eight groups: photosynthesis, TCA cycle, sugar transport, sugar metabolism, nitrogen transport, nitrogen reduction, amino acid metabolism and nitrogen regulation. Additionally, a total of 78,306 alternative splicing events have been identified, which primarily belong to alternative 5' donor sites, alternative 3' acceptor sites, intron retention and exon skipping. In sRNA sequencing, four carbon and nitrogen metabolism-related miRNAs (osa-miR1440b, osa-miR2876-5p, osa-miR1877 and osa-miR5799 were determined to be regulated by natural light/dark cycle. The expression level analysis showed that the four carbon and nitrogen metabolism-related miRNAs negatively regulated their target genes. These results may provide a good strategy to study how natural light/dark cycle regulates carbon and nitrogen metabolism to ensure plant

  5. Environmental regulations and business decisions

    OpenAIRE

    Gray, Wayne B.

    2015-01-01

    Environmental regulations raise production costs at regulated firms, though in most cases the costs are only a small fraction of a firm’s total costs. Productivity tends to fall, and firms may shift new investment and production to locations with less stringent regulation. However, environmental regulations have had enormous benefits in terms of lives saved and illnesses averted, especially through reductions in airborne particulates. The potential health gains may be even greater in developi...

  6. Efeitos de herbicidas nos teores de macronutrientes e nas características tecnológicas da cana-de-açúcar (Saccharum spp.. I - Misturas de herbicidas em pós-emergência Effect of herbicides on the macronutrient levels and on the tecnologic characteristics of sugarcane (Saccharum spp. I - Mixtures of postemergence herbicides

    Directory of Open Access Journals (Sweden)

    R. Victoria Filho

    1980-12-01

    + 2,3,6-TBA + pendimethalin. Aos cinco meses o teor de P foi diminuido pela mistura de ametryne + secbumetone + 2,4-D, e o teor de Ca decresceu pelas misturas de diuron + 2,4-D, ametryne + 2,4-D, alachlor + 2,4-D, asulam + ioxynil + 2,4-D, MCPA + 2,4-D, oxadiazon + 2,4-D, ametryne + simazine + 2,4-D e ametryne + secbumetone + 2,4-D. Já aos oito meses não houve diferença estatística para qualquer dos nutrientes estudados. Os teores de pol/ha e produção de colmos/ha não foram significativamente afetados por qualquer dos tratamentos quando comparados com a testemunha com capina. Todavia, todos os tratamentos apresentaram produção inferior a esta, sugerindo certa precaução com as aplicações pós-emergentes em canade-açúcar.The present research was conducted in the São Carlos Sugar Mill. Jaboticabal - SP in a oxisol (Latossolic B containing 3,9% organic matter. with the obje tive to study the behavior of the main post-emergence herbicide mixtures, in the sugarcane crop for weed control, and their interferences on the macronutrient levels and development of CB 41-14 variety. The treatments in kg of active ingredient per hectare were: ametryne + 2,4-D (comercial formulation at 1,47 -t 2,03; diuron + 2,4-D at 1,60 + 2,16: ametryne + 2,4-D at 1,60 + 2,16; alachlor + 2,4-D at 1,09 + 1,08; asulam + ioxynil 2,4 -D at 2,8 + 1,75; MCPA + 2,4-D at 0,83 + 0,83; oxadiazon 2,4-D at 0,50 + 2,16; ametryne + simazine + 2,4-D at 1,25 1,25 + 2,16; ametryn + secbumeton + 2,4 -D at 2,00 + 2,00 + 2,16; diuron + hexazinone + surfactant at 0,80 + 0,45 + 0,5% and MCPA + 2,3 ,6 -TBA + pendimethalin + surfactant at 1,50 + 0,48 + 0,66 + 0,5% . The weed control was evaluated by counting the surviving weeds, and by visual evaluation according to the scale of the "AssociacionLatinoamericana de Malezas" (ALAM. The effects on the crop were evaluated by counting the fresh-emerging sugarcane plants, visual evaluating of herbicide injuries, analysis of macronutrients levels in the leaves at

  7. [Regulation of terpene metabolism

    Energy Technology Data Exchange (ETDEWEB)

    Croteau, R.

    1992-01-01

    This report describes accomplishments over the past year on understanding of terpene synthesis in mint plants and sage. Specifically reported are the fractionation of 4-S-limonene synthetase, the enzyme responsible for the first committed step to monoterpene synthesis, along with isolation of the corresponding RNA and DNA cloning of its gene; the localization of the enzyme within the oil glands, regulation of transcription and translation of the synthetase, the pathway to camphor biosynthesis,a nd studies on the early stages and branch points of the isoprenoid pathway.

  8. FACTORS REGULATING LIBERAL TRANSLATION

    Institute of Scientific and Technical Information of China (English)

    龚海红

    2012-01-01

    Literal translation and liberal translation are two important methods and both play key roles in translation.However,some textbooks say that most translations are literal translations while others maintain most are liberal ones,besides,some others suggest a combination of the two.This paper focuses on the facts that regulate liberal translation.Because of the differences in culture,society,history,geography,and so on,there exists a great difference between Chinese language and English language,which does naturally lead to the liberal translation.

  9. The regulation of hunting

    DEFF Research Database (Denmark)

    Abildtrup, Jens; Jensen, Frank

    of the individual harvest. However, information about the individual harvest may be costly to obtain. Thus, we may have to look for alternatives to the existing system. This paper proposes a population tax/subsidy as an alternative which is the difference between the actual and optimal population multiplied...... by an individual, variable tax rate. The variable tax rate is, among other things, based on the difference in marginal value of the population between the hunter and the regulator. The paper shows that the population tax/subsidy secures a first-best optimum. Thus, the population tax is a good alternative...

  10. Wiring regulations in brief

    CERN Document Server

    Tricker, Ray

    2012-01-01

    Tired of trawling through the Wiring Regs?Perplexed by Part P?Confused by cables, conductors and circuits?Then look no further! This handy guide provides an on-the-job reference source for Electricians, Designers, Service Engineers, Inspectors, Builders, Students, DIY enthusiastsTopic-based chapters link areas of working practice - such as cables, installations, testing and inspection, special locations - with the specifics of the Regulations themselves. This allows quick and easy identification of the official requirements relating to the situati

  11. Regulation of the cyanobacterial CO2-concentrating mechanism involves internal sensing of NADP+ and α-ketogutarate levels by transcription factor CcmR.

    Directory of Open Access Journals (Sweden)

    Shawn M E Daley

    Full Text Available Inorganic carbon is the major macronutrient required by organisms utilizing oxygenic photosynthesis for autotrophic growth. Aquatic photoautotrophic organisms are dependent upon a CO(2 concentrating mechanism (CCM to overcome the poor CO(2-affinity of the major carbon-fixing enzyme, ribulose-bisphosphate carboxylase/oxygenase (Rubisco. The CCM involves the active transport of inorganic forms of carbon (C(i into the cell to increase the CO(2 concentration around the active site of Rubisco. It employs both bicarbonate transporters and redox-powered CO(2-hydration enzymes coupled to membranous NDH-type electron transport complexes that collectively produce C(i concentrations up to a 1000-fold greater in the cytoplasm compared to the external environment. The CCM is regulated: a high affinity CCM comprised of multiple components is induced under limiting external Ci concentrations. The LysR-type transcriptional regulator CcmR has been shown to repress its own expression along with structural genes encoding high affinity C(i transporters distributed throughout the genome of Synechocystis sp. PCC 6803. While much has been learned about the structural genes of the CCM and the identity of the transcriptional regulators controlling their expression, little is known about the physiological signals that elicit the induction of the high affinity CCM. Here CcmR is studied to identify metabolites that modulate its transcriptional repressor activity. Using surface plasmon resonance (SPR α-ketoglutarate (α-KG and the oxidized form of nicotinamide adenine dinucleotide phosphate (NADP(+ have been identified as the co-repressors of CcmR. Additionally, ribulose-1,5-bisphosphate (RuBP and 2-phosphoglycolate (2-PG have been confirmed as co-activators of CmpR which controls the expression of the ABC-type bicarbonate transporter.

  12. The Regulation of Street Foods

    DEFF Research Database (Denmark)

    Forkour, John Boulard; Samuelsen, Helle; Yeboah, Eric Henry

    2017-01-01

    the challenges and negotiating strategies of regulators of street-vended foods in Ghana and analyses the implication for their relationship with street food vendors. The paper reveals that regulators operate in a context of limited resources, leading to a general feeling of neglect. In coping, regulators adopt...

  13. Produção de biomassa e teor de macronutrientes do milheto, feijão-de-porco e guandu-anão em cultivo solteiro e consorciado Biomass production and macronutrients quantity of millet, jack bean, guandu single and in intercropping

    Directory of Open Access Journals (Sweden)

    Cícero Monti Teixeira

    2005-02-01

    Full Text Available Objetivou-se determinar a produção de biomassa e o teor de macronutrientes do milheto (Pennisetum typhoides (Burm. Stapf, feijão-de-porco (Canavalia ensiformes (L. DC. e guandu-anão (Cajanus cajan (L. Millsp. em cultivo solteiro e nos consórcios da gramínea com as leguminosas, visando a produção de palha no sistema plantio direto. O trabalho foi conduzido no campo experimental do Departamento de Agricultura da Universidade Federal de Lavras (Lavras, MG, Brasil. O delineamento foi o de blocos casualizados, com cinco tratamentos e quatro repetições. Apenas o guandu-anão solteiro apresentou menor produção de fitomassa fresca e seca, sendo que os demais tratamentos não diferiram entre si, pelo teste de Tukey a 5% de probabilidade. De forma geral, as leguminosas apresentaram maiores teores de N e Ca e o milheto maiores teores de S. Apenas o feijão-de-porco solteiro apresentou menor teor de P. Os maiores teores de K foram apresentados pelo milheto solteiro e consorciado com as leguminosas e pelo feijão-de-porco em consórcio com milheto. Os menores teores de Mg foram verificados para o guandu-anão.The object of this work was to evaluate the biomass production and the macronutrients quantity of millet (Pennisetum typhoides (Burm. Stapf, jack bean (Canavalia ensiformes (L. DC., guandu (Cajanus cajan, (L. Millsp. dwarf cultivar, and the millet with leguminous consortiums to straw production in no-tillage system. The experiment was carried in experimental area at Agriculture Department of the Federal University of Lavras (Lavras, Minas Gerais state, Brazil. The experimental design was randomized blocks, with five treatments and four replications. For biomass production, only the guandu presented smaller fresh and dry biomass yield than the other treatments. In general, the leguminous presented the greatest N and Ca quantities and millet the greatest quantities of S. Only jack bean presented minor P quantity. For K the greatest quantities

  14. [Regulation of terpene metabolism

    Energy Technology Data Exchange (ETDEWEB)

    Croteau, R.

    1991-01-01

    During the last grant period, we have completed studies on the key pathways of monoterpene biosynthesis and catabolism in sage and peppermint, and have, by several lines of evidence, deciphered the rate-limiting step of each pathway. We have at least partially purified and characterized the relevant enzymes of each pathway. We have made a strong case, based on analytical, in vivo, and in vitro studies, that terpene accumulation depends upon the balance between biosynthesis and catabolism, and provided supporting evidence that these processes are developmentally-regulated and very closely associated with senescence of the oil glands. Oil gland ontogeny has been characterized at the ultrastructural level. We have exploited foliar-applied bioregulators to delay gland senescence, and have developed tissue explant and cell culture systems to study several elusive aspects of catabolism. We have isolated pure gland cell clusters and localized monoterpene biosynthesis and catabolism within these structures, and have used these preparations as starting materials for the purification to homogeneity of target regulatory'' enzymes. We have thus developed the necessary background knowledge, based on a firm understanding of enzymology, as well as the necessary experimental tools for studying the regulation of monoterpene metabolism at the molecular level. Furthermore, we are now in a position to extend our systematic approach to other terpenoid classes (C[sub 15]-C[sub 30]) produced by oil glands.

  15. Buck/boost regulator

    Science.gov (United States)

    Paulkovich, J.; Rodriguez, G. E. (Inventor)

    1981-01-01

    A voltage regulated DC to DC converter uses an inductor and a capacitor as storage elements. The inductor is composed of two windings having a common junction. A transformer with a center tap connected to the common junction of the two windings is connected at either end of its winding to ground through controlled switches. One winding of the inductor and either end of the transformer winding are connected by power diodes to the capacitor which supplies the output voltage to a load. The other winding of the inductor is connected to a fourth power diode as a clamping diode. Input voltage is supplied to the inductor through a third controlled switch. A pulse width modulator connected to the output of the converter alternately closes and opens the switches connected to either end of the transformer winding and also closes the switch supplying input voltage to the inductor each time either of the switches connected to the ends of the transformer winding are closed. The duty cycle of the closing and opening of the several switches is adjusted by the pulse modulator to regulate the output voltage.

  16. Regulations and Procedures Manual

    Energy Technology Data Exchange (ETDEWEB)

    Young, Lydia J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2011-07-25

    The purpose of the Regulations and Procedures Manual (RPM) is to provide LBNL personnel with a reference to University and Lawrence Berkeley National Laboratory (LBNL or Laboratory) policies and regulations by outlining normal practices and answering most policy questions that arise in the day-to-day operations of Laboratory organizations. Much of the information in this manual has been condensed from detail provided in LBNL procedure manuals, Department of Energy (DOE) directives, and Contract DE-AC02-05CH11231. This manual is not intended, however, to replace any of those documents. RPM sections on personnel apply only to employees who are not represented by unions. Personnel policies pertaining to employees represented by unions may be found in their labor agreements. Questions concerning policy interpretation should be directed to the LBNL organization responsible for the particular policy. A link to the Managers Responsible for RPM Sections is available on the RPM home page. If it is not clear which organization is responsible for a policy, please contact Requirements Manager Lydia Young or the RPM Editor.

  17. Circadian rhythms regulate amelogenesis.

    Science.gov (United States)

    Zheng, Li; Seon, Yoon Ji; Mourão, Marcio A; Schnell, Santiago; Kim, Doohak; Harada, Hidemitsu; Papagerakis, Silvana; Papagerakis, Petros

    2013-07-01

    Ameloblasts, the cells responsible for making enamel, modify their morphological features in response to specialized functions necessary for synchronized ameloblast differentiation and enamel formation. Secretory and maturation ameloblasts are characterized by the expression of stage-specific genes which follows strictly controlled repetitive patterns. Circadian rhythms are recognized as key regulators of the development and diseases of many tissues including bone. Our aim was to gain novel insights on the role of clock genes in enamel formation and to explore the potential links between circadian rhythms and amelogenesis. Our data shows definitive evidence that the main clock genes (Bmal1, Clock, Per1 and Per2) oscillate in ameloblasts at regular circadian (24 h) intervals both at RNA and protein levels. This study also reveals that the two markers of ameloblast differentiation i.e. amelogenin (Amelx; a marker of secretory stage ameloblasts) and kallikrein-related peptidase 4 (Klk4, a marker of maturation stage ameloblasts) are downstream targets of clock genes. Both, Amelx and Klk4 show 24h oscillatory expression patterns and their expression levels are up-regulated after Bmal1 over-expression in HAT-7 ameloblast cells. Taken together, these data suggest that both the secretory and the maturation stages of amelogenesis might be under circadian control. Changes in clock gene expression patterns might result in significant alterations of enamel apposition and mineralization.

  18. The Quality of Regulation

    Directory of Open Access Journals (Sweden)

    Emil BĂLAN

    2011-11-01

    Full Text Available Good governance also involves the affirmation and practice of some principles that allow the structures of the public space to administrate the general interest in the respect of the democracy and of the state of law pre-requisites, as well as the ones of a good administration: trust and predictability, openness and transparency, responsibility, efficiency and efficacy. The assurance of such desideratum imposes that the rules invested with the force of law, applicable to the juridical rapports to be clear, not equivoques, predictable, to allow both the protection of public interest and the respect of the citizens’ dignity and interests. The evaluation of the quality of regulation represents a necessary process of the appreciation of the impact that juridical norms are intended to produce and measures in which the outcomes of the implementation correspond to the ones established during the stage of formulating the public policy. The study tries to identify ways of evaluating the quality of regulation, valid in a social and political space governed by democratic rules and principles.

  19. Regulations and Procedures Manual

    Energy Technology Data Exchange (ETDEWEB)

    Young, Lydia [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2010-09-30

    The purpose of the Regulations and Procedures Manual (RPM) is to provide Laboratory personnel with a reference to University and Lawrence Berkeley National Laboratory policies and regulations by outlining the normal practices and answering most policy questions that arise in the day-to-day operations of Laboratory departments. Much of the information in this manual has been condensed from detail provided in Laboratory procedure manuals, Department of Energy (DOE) directives, and Contract DE-AC02-05CH11231. This manual is not intended, however, to replace any of those documents. The sections on personnel apply only to employees who are not represented by unions. Personnel policies pertaining to employees represented by unions may be found in their labor agreements. Questions concerning policy interpretation should be directed to the department responsible for the particular policy. A link to the Managers Responsible for RPM Sections is available on the RPM home page. If it is not clear which department should be called, please contact the Associate Laboratory Director of Operations.

  20. Personalized weight loss strategies - the role of macronutrient distribution

    DEFF Research Database (Denmark)

    Martinez, J Alfredo; Navas-Carretero, Santiago; Saris, Wim H M

    2014-01-01

    A large number of different dietary approaches have been studied in an attempt to achieve healthy, sustainable weight loss among individuals with overweight and obesity. Restriction of energy intake is the primary method of producing a negative energy balance leading to weight loss. However, owin...

  1. Requerimientos de macronutrientes y micronutrientes Requeriments of macronutrients and micronutrients

    OpenAIRE

    C. Ortiz Leyba; V. Gómez-Tello; C. Serón Arbeloa

    2005-01-01

    Los pacientes críticos presentan modificaciones importantes en sus requerimientos energéticos, en las que intervienen la situación clínica, el tratamiento aplicado y el momento evolutivo. Por ello, el método más adecuado para el cálculo del aporte calórico es la calorímetria indi-recta. En ausencia de la misma, puede recurrirse al empleo de fórmulas como la de Harris-Benedict, aunque sin utilizar de factores de corrección tan elevados como los recomendados con anterioridad, con el fin de evit...

  2. Infrared analysis for determining macronutrients in human milk

    DEFF Research Database (Denmark)

    Michaelsen, K F; Pedersen, S B; Skafte, L

    1988-01-01

    analysis were compared with those of the following reference methods: protein--Kjeldahl (nitrogen minus nonprotein nitrogen); fat--Roese Gottlieb; carbohydrate--lactose enzymatic assay; energy--bomb calorimetry. The precision (repeatability coefficient of variation) of the IR results was high for all four...... and the results of the lactose assay was poor, probably because the oligosaccharides in the milk were included in the results from the IR analysis and not in the results from the lactose assay. IR analysis is a valuable method in research, especially in epidemiological surveys, in which large numbers of samples...

  3. Evaluation of energy and macronutrient intake of black women in ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-11-19

    Nov 19, 2008 ... 2Department of Nutrition and Dietetics, University of the Free State, 3PAREXEL, Bloemfontein, South Africa. 4Department ... nutrition, diet-related chronic diseases are now becoming ..... South Africa: National Academy. Press ...

  4. Requerimientos de macronutrientes y micronutrientes Requeriments of macronutrients and micronutrients

    Directory of Open Access Journals (Sweden)

    C. Ortiz Leyba

    2005-06-01

    Full Text Available Los pacientes críticos presentan modificaciones importantes en sus requerimientos energéticos, en las que intervienen la situación clínica, el tratamiento aplicado y el momento evolutivo. Por ello, el método más adecuado para el cálculo del aporte calórico es la calorímetria indi-recta. En ausencia de la misma, puede recurrirse al empleo de fórmulas como la de Harris-Benedict, aunque sin utilizar de factores de corrección tan elevados como los recomendados con anterioridad, con el fin de evitar aportes hipercalóricos. El aporte de una cantidad calórica fija (comprendida entre 25-30 Kcal/Kg/dia es adecuado para la mayoría de los pacientes críticos. La administración de carbohidratos debe tener un límite máximo de 5 g/Kg/día. Deben controlarse los niveles de glucemia plasmática con el fin de evitar la hiperglucemia. Respecto al aporte de grasa, el límite máximo debería ser el de 1,5 g/Kg/día. El aporte proteico recomendado se encuentra entre 1,0 y 1,5 gr/Kg/dia, en función de las características de la situación clínica. Debe prestarse una atención especial al aporte de micronutrientes, un aspecto que habitualmente es infravalorado. En este sentido, existen datos para considerar que algunos oligoelementos, como Zn, Cu, Mn, Cr, Se, Mo, y algunas de las vitaminas (A,B,C,E son de gran importancia para los pacientes en situación crítica, aunque los requerimientos específicos para cada uno de ellos no han sido establecidos.Critically ill patients have important modifications in their energetic requirements, in which the clinical situation, treatment applied and the time course take part. Thus, the most appropriate method to calculate the caloric intake is indirect calorimetry. When this test is not available, calculations such as Harris-Benedict's may be used, although not using the so high correction factors as previously recommended in order to avoid hypercaloric intakes. The in-take of a fixed caloric amount (comprised between 25-30 Kcal/Kg/min is adequate for most critically ill patients. Carbohydrates intake must be of 5 g/kg/day maximum. Glucose plasma levels must be controlled in order to avoid hyperglycemia. With regards to fat intake, the maximum limit should be 1.5 g/kg/day. The recommended protein intake is 1.0-1.5 g/kg/day, according to the clinical situation characteristics. Special care must be taken with micronutrients intake, an issue that is many times undervalued. In this sense, there are data to consider some micronutrients such as Zn, CU, Mn, Cr, Se, Mo and some vitamins (A, B, C, and E of great importance for patients in a critical condition, although specific requirements for each one of them have not been established.

  5. Macronutrient Supplementation and Food Prices in HIV Treatment12

    OpenAIRE

    Sztam, Kevin A.; Fawzi, Wafaie W.; Duggan, Christopher

    2010-01-01

    Infection caused by HIV and malnutrition have a complex interaction and often coexist geographically. Malnutrition has synergistic immune effects and HIV affects nutritional status. HIV care and treatment programs are compelled to confront this dual burden to optimize HIV outcomes. In this article, we review the published literature concerning intervention studies in adults and children and the effect of food prices on HIV treatment programs. While the evidence base is relatively incomplete f...

  6. Macronutrients removal in the treatment of swine wastewater

    Directory of Open Access Journals (Sweden)

    Violeta E. Escalante Estrada

    2012-09-01

    Full Text Available A review (2004-2011 reveals that, the biological processes that have been studied mostly for pig effluent treatment, are: anaerobic digesters, upflow anaerobic sludge reactors, anaerobic filters, secuential batch reactors, lagoon systems and biofilters. From a comparison between the operational characteristics and the pollutants removal efficiency reported for those different processes; it could be concluded that a good treatment option could be a combined system of anaerobic filter submerged followed by an aerated trickling filter; since anaerobic filters require less hydraulic retention time to reduce the organic matter and, moreover, the biofilter can reach nitrogen removal efficiencies greater than those of other systems (lagoons, activated sludge variations, etc. However, although there are some studies on monitoring mechanisms for nitrogen removal in biofilters, it requires further studies in this regard. It is proposed that a possible strategy would be studying the effect of the C/N ratio and the aeration rate in these treatment systems.

  7. Food reinforcement, energy intake, and macronutrient choice123

    OpenAIRE

    Epstein, Leonard H.; Carr, Katelyn A; Lin, Henry; Fletcher, Kelly D.

    2011-01-01

    Background: Food is a powerful reinforcer that motivates people to eat. The relative reinforcing value of food (RRVfood) is associated with obesity and energy intake and interacts with impulsivity to predict energy intake.

  8. The endocannabinoid system: directing eating behavior and macronutrient metabolism

    OpenAIRE

    Bruce Alan Watkins; Jeffrey eKim

    2015-01-01

    For many years, the brain has been the primary focus for research on eating behavior. More recently, the discovery of the endogenous endocannabinoids (EC) and the endocannabinoid system (ECS), as well as the characterization of its actions on appetite and metabolism, has provided greater insight on the brain and food intake. The purpose of this review is to explain the actions of EC in the brain and other organs as well as their precursor polyunsaturated fatty acids (PUFA) that are converte...

  9. The endocannabinoid system: directing eating behavior and macronutrient metabolism

    OpenAIRE

    Watkins, Bruce A.; Kim, Jeffrey

    2015-01-01

    For many years, the brain has been the primary focus for research on eating behavior. More recently, the discovery of the endocannabinoids (EC) and the endocannabinoid system (ECS), as well as the characterization of its actions on appetite and metabolism, has provided greater insight on the brain and food intake. The purpose of this review is to explain the actions of EC in the brain and other organs as well as their precursor polyunsaturated fatty acids (PUFA) that are converted to these en...

  10. Central insulin and macronutrient intake in the rat

    NARCIS (Netherlands)

    Chavez, M; Riedy, CA; VanDijk, G; Woods, SC; Riedy, Christine A.; Woods, Stephen C.

    1997-01-01

    When rats are maintained on a standard laboratory diet, the infusion of low doses of insulin into the cerebroventricular system causes a reduction of food intake and body weight. It was recently reported that, if rats are maintained on a high-fat diet (56% calories as fat), they are insensitive to t

  11. Pediatric parenteral nutrition: putting the microscope on macronutrients and micronutrients.

    Science.gov (United States)

    Slicker, Julie; Vermilyea, Sarah

    2009-01-01

    Parenteral nutrition can be a life-saving therapy, but its benefits need to be balanced with a unique set of risks and complications. Methods of practice vary because there is a dearth of research in the area of pediatric parenteral nutrition. This article reviews the available literature on parenteral nutrition in children and provides suggestions on prevention and management of parenteral nutrition-associated liver disease. Some of the issues discussed in this article include glucose infusion rates, cycling of parenteral nutrition, copper and manganese toxicity, and the provision of glutamine, selenium, and carnitine.

  12. Regulation as delegation

    Directory of Open Access Journals (Sweden)

    Oren Bar-Gill

    2016-03-01

    Full Text Available Objective to consider the conception of reverse delegation when the government acts a principal and an individual ndash an agent from the point of view of behavioral PrincipalAgent Theory. Methods statistical method sociological polling. Results In diverse areas ndash from retirement savings to consumer credit to prescription drug use to fuel economy and energy efficiency rules to tobacco consumption to food and beverage consumption ndash government makes decisions for us or endeavors to help us make better decisions thus serving as our agent. From the point of view of PrincipalAgent Theory and behavioral PrincipalAgent Theory a great deal of modern regulation can be helpfully evaluated as a hypothetical delegation. Shifting from personal decisions to public goods problems the authors view the idea of reverse delegation with the government as principal and the individuals as agents. They show that the essence of delegation changes depending on the context. The article describes conditions under which various approaches will make sense. Scientific novelty the paper is devoted to the foreign experience of regulation through delegation by the example of a country with developed market economy the USA. It shows the prospects of such approach in solving both the public and the private tasks. Application of PrincipalAgent Theory and behavioral PrincipalAgent Theory is viewed to distinguish between such types of hypothetical delegation as information default rules incentives precommitments mandates and prohibitions. The article considers the benefits and costs of delegation and circumstances in which one or another approach makes sense. Practical significance PrincipalAgent Theory is widely used in economics and political science and can serve as a convenient tool to consider the optimal scale and essence of the assistance rendered to us by the government as our agent. The paper is of interest for the Russian legal science as the institution of

  13. Liberação de macronutrientes das palhadas de milheto solteiro e consorciado com feijão-de-porco sob cultivo de feijão Macronutrient release from straw of millet and millet - jack - bean intercropping under common bean

    Directory of Open Access Journals (Sweden)

    Cícero Monti Teixeira

    2010-04-01

    matéria seca e maiores teores de N e Ca, ciclando maior quantidade de todos os macronutrientes. A palhada de milheto + feijão-de-porco apresentou maiores velocidades de decomposição e liberação de N, Ca e Mg.Nutrients recycle is related to the absorption capacity by different cover crop species. Already speeds of decomposition and of nutrient release of straws produced is mostly related with C/N ratio, with a marked difference between grasses and leguminous. In this sense, the objective of this study was to evaluate the biomass production and macronutrient contents and accumulation, decomposition, and nutrient release from straw of millet (Pennisetum typhoides (Burm. Stapf and millet - jack - bean (Canavalia ensiformes (L. DC. intercropping, under field conditions, under common bean, sown in August (winter/spring. Decomposition and nutrient release was determined in nylon bags (0.2 x 0.2 m, 1 mm mesh filled with straw quantities according to the area of the bag. The experimental design was randomized blocks with four replications in split plot arrangement. The straws represented the plots and the subplots evaluation periods (0, 8, 16, 24, 40, 56, and 72 days. The residues were dried to constant weight in a forced-air oven at 65 ºC to determine the remaining dry matter, then ground and sent to a laboratory to analyze macronutrient contents. Based on the contents and remaining dry matter amounts, the remaining nutrient amounts were determined, expressed in relation to the initial amount. Non-linear models were fit to the values, choosing the best adjustment in each case. Biomass quantity, N and Ca contents and cycling of nutrient quantities was greatest in the intercropping straw. The decomposition and nutrient release speeds were also highest in millet - jack - bean intercropping straw.

  14. Acúmulo de macronutrientes na soja influenciado pelo cultivo prévio do capim-marandu, correção e compactação do solo Macronutrient accumulation in the soybean influenced by prior cultivation of Marandu grass and soil remediation and compaction

    Directory of Open Access Journals (Sweden)

    Marcos André Silva Souza

    2012-12-01

    Full Text Available O presente trabalho foi desenvolvido com o objetivo de avaliar o efeito do cultivo prévio do capim-Marandu (Brachiaria brizantha cv. Marandu, da aplicação de corretivos e da compactação do solo no acúmulo de macronutrientes pela soja cultivada em sucessão. O delineamento experimental foi inteiramente casualizado em esquema fatorial 4 x 6 x 2, com três repetições. Os fatores de estudo foram quatro densidades do solo: 1,0; 1,20; 1,40 e 1,60 Mg m-3; seis tratamentos de correção: 1 controle, sem correção; 2 calcário; 3 silicato de cálcio; 4 gesso; 5 calcário + gesso; 6 silicato de cálcio + gesso; além de dois sistemas de cultivo: com e sem cultivo prévio do capim-Marandu. As unidades experimentais foram compostas por vasos de tubos de PVC de 20 cm de diâmetro, compostos por dois anéis: o anel inferior, de 40 cm de altura, recebeu o solo sob condições naturais e densidade de 1,0 Mg m-3; o anel superior, com 20 cm de altura representando 6,28 dm³, recebeu os tratamentos de densidades, correção e gesso como descrito adiante. Em cada um foram conduzidas três plantas de soja (cv. Conquista até o final do ciclo, quando o acúmulo de macronutrientes pela cultura foi avaliado. Os resultados mostraram que o cultivo prévio do capim-Marandu e o uso de corretivos amenizaram os efeitos negativos da compactação do solo sobre a nutrição da soja. A utilização de corretivos do solo contribuiu para o aumento no acúmulo de macronutrientes na parte aérea da soja, porém o incremento na compactação diminuiu o acúmulo de N, P, K, Ca, Mg e S. A compactação do solo persistiu parcialmente mediante o cultivo prévio com o capim marandu.The present work was developed with the objective of evaluating the effect of the prior cultivation of marandu grass (Brachiaria brizantha cv. Marandu, conditioning applications and soil compaction on macronutrient accumulation in soybeans grown under successive cultivation. The experimental design

  15. Hormonal Regulators of Appetite

    Directory of Open Access Journals (Sweden)

    Juliana Austin

    2009-01-01

    Full Text Available Obesity is a significant cause of morbidity and mortality worldwide. There has been a significant worsening of the obesity epidemic mainly due to alterations in dietary intake and energy expenditure. Alternatively, cachexia, or pathologic weight loss, is a significant problem for individuals with chronic disease. Despite their obvious differences, both processes involve hormones that regulate appetite. These hormones act on specific centers in the brain that affect the sensations of hunger and satiety. Mutations in these hormones or their receptors can cause substantial pathology leading to obesity or anorexia. Identification of individuals with specific genetic mutations may ultimately lead to more appropriate therapies targeted at the underlying disease process. Thus far, these hormones have mainly been studied in adults and animal models. This article is aimed at reviewing the hormones involved in hunger and satiety, with a focus on pediatrics.

  16. Hormonal Regulators of Appetite

    Directory of Open Access Journals (Sweden)

    Austin Juliana

    2008-11-01

    Full Text Available Obesity is a significant cause of morbidity and mortality worldwide. There has been a significant worsening of the obesity epidemic mainly due to alterations in dietary intake and energy expenditure. Alternatively, cachexia, or pathologic weight loss, is a significant problem for individuals with chronic disease. Despite their obvious differences, both processes involve hormones that regulate appetite. These hormones act on specific centers in the brain that affect the sensations of hunger and satiety. Mutations in these hormones or their receptors can cause substantial pathology leading to obesity or anorexia. Identification of individuals with specific genetic mutations may ultimately lead to more appropriate therapies targeted at the underlying disease process. Thus far, these hormones have mainly been studied in adults and animal models. This article is aimed at reviewing the hormones involved in hunger and satiety, with a focus on pediatrics.

  17. Mitosis and its regulation

    Directory of Open Access Journals (Sweden)

    Frías Vázquez Sara

    2014-07-01

    Full Text Available Cell division by mitosis is essential for the development of organisms and their reproduction; it is also neces- sary that each new cell is genetically identical to that from which it comes. In eukaryotes this is achieved by the presence of complex mechanisms that ensure the integrity of genomic material and their proper segregation during mitosis. The traditional view of mitosis has been divided into different stages that were characterized by morphological studies in dividing cells; advances in molecular biology have led beyond this characterization, so that we now know a range of participant molecules. This article will discuss the process of mitosis, both at the cellular and molecular level and a brief summary of the molecular players that regulate this process.

  18. Meat and Appetite Regulation

    DEFF Research Database (Denmark)

    Kehlet, Ursula Nana

    D thesis was to investigate the effects of fiber addition to meatballs and the effects of cooking methods of pork on appetite regulation. The PhD thesis is based on three human meal test studies and one analytical study related to the characteristics of fiber meat products. In paper I, the objective...... pork products are also characterized as high fat products containing more than 10 g fat per 100 g. In this context, the Danish meat industry puts a lot of effort into developing meat products with a healthier nutritional profile. Thus, it is relevant to provide scientific evidence of the satiating...... effects of new formulations of pork products. Different strategies can be applied to potentially enhance the satiating properties of pork. Processed meat products such as meatballs can serve as a matrix for the addition of fiber ingredients. Based on their high protein and fiber contents, high...

  19. Magnetostrictive Pressure Regulating System

    Science.gov (United States)

    Richard, James A. (Inventor); Pickens, Herman L. (Inventor)

    2013-01-01

    A magnetostrictive pressure regulating system includes a magnetostrictive valve that incorporates a magnetostrictive actuator with at least one current-carrying coil disposed thereabout. A pressure force sensor, in fluid communication with the fluid exiting the valve, includes (i) a magnetostrictive material, (ii) a magnetic field generator in proximity to the magnetostrictive material for inducing a magnetic field in and surrounding the magnetostrictive material wherein lines of magnetic flux passing through the magnetostrictive material are defined, and (iii) a sensor positioned adjacent to the magnetostrictive material and in the magnetic field for measuring changes in at least one of flux angle and flux density when the magnetostrictive material experiences an applied force that is aligned with the lines of magnetic flux. The pressure of the fluid exiting the valve causes the applied force. A controller coupled to the sensor and to the current-carrying coil adjusts a current supplied to the current-carrying coil based on the changes so-measured.

  20. NCAM regulates cell motility

    DEFF Research Database (Denmark)

    Prag, Søren; Lepekhin, Eugene A; Kolkova, Kateryna

    2002-01-01

    Cell migration is required during development of the nervous system. The regulatory mechanisms for this process, however, are poorly elucidated. We show here that expression of or exposure to the neural cell adhesion molecule (NCAM) strongly affected the motile behaviour of glioma cells...... independently of homophilic NCAM interactions. Expression of the transmembrane 140 kDa isoform of NCAM (NCAM-140) caused a significant reduction in cellular motility, probably through interference with factors regulating cellular attachment, as NCAM-140-expressing cells exhibited a decreased attachment...... to a fibronectin substratum compared with NCAM-negative cells. Ectopic expression of the cytoplasmic part of NCAM-140 also inhibited cell motility, presumably via the non-receptor tyrosine kinase p59(fyn) with which NCAM-140 interacts. Furthermore, we showed that the extracellular part of NCAM acted as a paracrine...

  1. Regulation of cholesterol homeostasis.

    Science.gov (United States)

    van der Wulp, Mariëtte Y M; Verkade, Henkjan J; Groen, Albert K

    2013-04-10

    Hypercholesterolemia is an important risk factor for cardiovascular disease. It is caused by a disturbed balance between cholesterol secretion into the blood versus uptake. The pathways involved are regulated via a complex interplay of enzymes, transport proteins, transcription factors and non-coding RNA's. The last two decades insight into underlying mechanisms has increased vastly but there are still a lot of unknowns, particularly regarding intracellular cholesterol transport. After decades of concentration on the liver, in recent years the intestine has come into focus as an important control point in cholesterol homeostasis. This review will discuss current knowledge of cholesterol physiology, with emphasis on cholesterol absorption, cholesterol synthesis and fecal excretion, and new (possible) therapeutic options for hypercholesterolemia.

  2. Regulation of Terpene Metabolism

    Energy Technology Data Exchange (ETDEWEB)

    Rodney Croteau

    2004-03-14

    OAK-B135 Research over the last four years has progressed fairly closely along the lines initially proposed, with progress-driven expansion of Objectives 1, 2 and 3. Recent advances have developed from three research thrusts: 1. Random sequencing of an enriched peppermint oil gland cDNA library has given access to a large number of potential pathway and regulatory genes for test of function; 2. The availability of new DNA probes and antibodies has permitted investigation of developmental regulation and organization of terpenoid metabolism; and 3. The development of a transformation system for peppermint by colleagues at Purdue University has allowed direct transgenic testing of gene function and added a biotechnological component to the project. The current status of each of the original research objectives is outlined below.

  3. Higher regulators, algebraic

    CERN Document Server

    Bloch, Spencer J

    2000-01-01

    This book is the long-awaited publication of the famous Irvine lectures. Delivered in 1978 at the University of California at Irvine, these lectures turned out to be an entry point to several intimately-connected new branches of arithmetic algebraic geometry, such as regulators and special values of L-functions of algebraic varieties, explicit formulas for them in terms of polylogarithms, the theory of algebraic cycles, and eventually the general theory of mixed motives which unifies and underlies all of the above (and much more). In the 20 years since, the importance of Bloch's lectures has not diminished. A lucky group of people working in the above areas had the good fortune to possess a copy of old typewritten notes of these lectures. Now everyone can have their own copy of this classic work.

  4. Probiotics and Appetite Regulation

    DEFF Research Database (Denmark)

    Bjerg, Anne Toksvig

    -armed parallel four weeks intervention study with W8 (1010 CFU) or placebo capsules was performed on young, normal to overweight participants. In the four weeks intervention study the effects of W8 on appetite, blood lipids, SCD1 activity and fecal microbiota were also investigated. Finally, associations between......Summary There is emerging focus on the gut microbiota’s (GM) effects on health. GM is suggested to be a contributing factor to the rapid development of obesity and its related diseases like type 2 diabetes and cardiovascular disease. The omposition of the GM has been associated with weight, insulin...... intestine, in an animal study and in two human studies the effect of the probiotic bacteria Lactobacillus paracasei subsp. paracasei L. casei W8 (W8) on appetite regulation, blood lipids and blood fatty acids. In addition, it was investigated if W8 had an effect on the fecal microbiota of the human...

  5. [Regulation of terpene metabolism

    Energy Technology Data Exchange (ETDEWEB)

    Croteau, R.

    1989-11-09

    Terpenoid oils, resins, and waxes from plants are important renewable resources. The objective of this project is to understand the regulation of terpenoid metabolism using the monoterpenes (C[sub 10]) as a model. The pathways of monoterpene biosynthesis and catabolism have been established, and the relevant enzymes characterized. Developmental studies relating enzyme levels to terpene accumulation within the oil gland sites of synthesis, and work with bioregulators, indicate that monoterpene production is controlled by terpene cyclases, the enzymes catalyzing the first step of the monoterpene pathway. As the leaf oil glands mature, cyclase levels decline and monoterpene biosynthesis ceases. Yield then decreases as the monoterpenes undergo catabolism by a process involving conversion to a glycoside and transport from the leaf glands to the root. At this site, the terpenoid is oxidatively degraded to acetate that is recycled into other lipid metabolites. During the transition from terpene biosynthesis to catabolism, the oil glands undergo dramatic ultrastructural modification. Degradation of the producing cells results in mixing of previously compartmentized monoterpenes with the catabolic enzymes, ultimately leading to yield decline. This regulatory model is being applied to the formation of other terpenoid classes (C[sub 15] C[sub 20], C[sub 30], C[sub 40]) within the oil glands. Preliminary investigations on the formation of sesquiterpenes (C[sub 15]) suggest that the corresponding cyclases may play a lesser role in determining yield of these products, but that compartmentation effects are important. From these studies, a comprehensive scheme for the regulation of terpene metabolism is being constructed. Results from this project wail have important consequences for the yield and composition of terpenoid natural products that can be made available for industrial exploitation.

  6. Regulation of melanopsin expression.

    Science.gov (United States)

    Hannibal, Jens

    2006-01-01

    Circadian rhythms in mammals are adjusted daily to the environmental day/night cycle by photic input via the retinohypothalamic tract (RHT). Retinal ganglion cells (RGCs) of the RHT constitute a separate light-detecting system in the mammalian retina used for irradiance detection and for transmission to the circadian system and other non-imaging forming processes in the brain. The RGCs of the RHT are intrinsically photosensitive due to the expression of melanopsin, an opsin-like photopigment. This notion is based on anatomical and functional data and on studies of mice lacking melanopsin. Furthermore, heterologous expression of melanopsin in non-neuronal mammalian cell lines was found sufficient to render these cells photosensitive. Even though solid evidence regarding the function of melanopsin exists, little is known about the regulation of melanopsin gene expression. Studies in albino Wistar rats showed that the expression of melanopsin is diurnal at both the mRNA and protein levels. The diurnal changes in melanopsin expression seem, however, to be overridden by prolonged exposure to light or darkness. Significant increase in melanopsin expression was observed from the first day in constant darkness and the expression continued to increase during prolonged exposure in constant darkness. Prolonged exposure to constant light, on the other hand, decreased melanopsin expression to an almost undetectable level after 5 days of constant light. The induction of melanopsin by darkness was even more pronounced if darkness was preceded by light suppression for 5 days. These observations show that dual mechanisms regulate melanopsin gene expression and that the intrinsic light-responsive RGCs in the albino Wistar rat adapt their expression of melanopsin to environmental light and darkness.

  7. Endocannabinoids in cerebrovascular regulation.

    Science.gov (United States)

    Benyó, Zoltán; Ruisanchez, Éva; Leszl-Ishiguro, Miriam; Sándor, Péter; Pacher, Pál

    2016-04-01

    The cerebral blood flow is tightly regulated by myogenic, endothelial, metabolic, and neural mechanisms under physiological conditions, and a large body of recent evidence indicates that inflammatory pathways have a major influence on the cerebral blood perfusion in certain central nervous system disorders, like hemorrhagic and ischemic stroke, traumatic brain injury, and vascular dementia. All major cell types involved in cerebrovascular control pathways (i.e., smooth muscle, endothelium, neurons, astrocytes, pericytes, microglia, and leukocytes) are capable of synthesizing endocannabinoids and/or express some or several of their target proteins [i.e., the cannabinoid 1 and 2 (CB1 and CB2) receptors and the transient receptor potential vanilloid type 1 ion channel]. Therefore, the endocannabinoid system may importantly modulate the regulation of cerebral circulation under physiological and pathophysiological conditions in a very complex manner. Experimental data accumulated since the late 1990s indicate that the direct effect of cannabinoids on cerebral vessels is vasodilation mediated, at least in part, by CB1 receptors. Cannabinoid-induced cerebrovascular relaxation involves both a direct inhibition of smooth muscle contractility and a release of vasodilator mediator(s) from the endothelium. However, under stress conditions (e.g., in conscious restrained animals or during hypoxia and hypercapnia), cannabinoid receptor activation was shown to induce a reduction of the cerebral blood flow, probably via inhibition of the electrical and/or metabolic activity of neurons. Finally, in certain cerebrovascular pathologies (e.g., subarachnoid hemorrhage, as well as traumatic and ischemic brain injury), activation of CB2 (and probably yet unidentified non-CB1/non-CB2) receptors appear to improve the blood perfusion of the brain via attenuating vascular inflammation.

  8. Standard types of regulation loops; Chaines de regulation types

    Energy Technology Data Exchange (ETDEWEB)

    Bertrand, M. [ENSAM, Centre d`Enseignement et de Recherche de Lille, 59 - Lille (France)

    1997-12-01

    The aim of this paper is to give help in the analysis of industrial regulation problems using different types of real installations. The increasing complexity of industrial systems requires the use of a decomposition-recomposition procedure using a scheme with different blocs. Examples are given to help the non-specialist users in the mastery of essential choices and in the distinction between operational and material separations. The examples concern: the heating loop of a central heating installation, the sensors and actuators of industrial systems (the temperature regulation of a tubular furnace, the electro-hydraulic positioning systems used in machine tools, forming, aeronautics etc.., the regulation of a mixing system for hot and cold fluids, and the regulation of a fluidizing system. The usual types of regulation loops are presented with the different steps of the resolution of a regulation problem. (J.S.) 7 refs.

  9. Branded prescription drug fee. Final regulations, temporary regulations, and removal of temporary regulations.

    Science.gov (United States)

    2014-07-28

    This document contains final regulations that provide guidance on the annual fee imposed on covered entities engaged in the business of manufacturing or importing branded prescription drugs. This fee was enacted by section 9008 of the Patient Protection and Affordable Care Act, as amended by section 1404 of the Health Care and Education Reconciliation Act of 2010. This document also withdraws the Branded Prescription Drug Fee temporary regulations and contains new temporary regulations regarding the definition of controlled group that apply beginning on January 1, 2015. The final regulations and the new temporary regulations affect persons engaged in the business of manufacturing or importing certain branded prescription drugs. The text of the temporary regulations in this document also serves as the text of proposed regulations set forth in a notice of proposed rulemaking (REG-123286-14) on this subject in the Proposed Rules section in this issue of the Federal Register.

  10. Regulation of the power sector

    CERN Document Server

    2013-01-01

    Regulation of the Power Sector is a unified, consistent and comprehensive treatment of the theories and practicalities of regulation in modern power-supply systems. The need for generation to occur at the time of use occasioned by the impracticality of large-scale electricity storage coupled with constant and often unpredictable changes in demand make electricity-supply systems large, dynamic and complex and their regulation a daunting task. Conceptually arranged in four parts, this book addresses both traditional regulatory frameworks and also liberalized and re-regulated environments. First, an introduction gives a full characterization of power supply including engineering, economic and regulatory viewpoints. The second part presents the fundamentals of regulation and the third looks at the regulation of particular components of the power sector in detail. Advanced topics and subjects still open or subject to dispute form the content of the fourth part. In a sector where regulatory design is the key driver...

  11. Nanomaterials: Regulation and Risk Assessment

    DEFF Research Database (Denmark)

    Hansen, Steffen Foss; Grieger, Khara Deanne; Baun, Anders

    2013-01-01

    The topics of regulation and risk assessment of nanomaterials have never been more relevant and controversial in Europe than they are at this point in time. In this entry, we present and discuss a number of major pieces of legislation relevant for the regulation of nanomaterials, including REACH...... Regulation. Chemical risk assessment provides a fundamental element in support of existing legislation. Risk assessment is normally said to consist of four elements, i.e., hazard identification, dose–response assessment, exposure assessment, and risk characterization. Each of these four elements hold......, the Water Framework Directive, pharmaceuticals regulation, and the Novel Foods Regulation. Current regulation of nanomaterials entail three overall challenges: 1) limitations in regard to terminology and definitions of key terms such as a “substance,” “novel food,” etc.; 2) safety assessment requirements...

  12. Sustainable regulation of construction.

    Science.gov (United States)

    2000-11-01

    The seminar examined the role building codes and regulations can have in promoting a more sustainable approach to construction, particularly through their application to non-industrial building materials. A range of building materials such as straw, bamboo, rammed earth, adobe, and cob (a mixture of clay and chopped straw) were described and illustrated by slides to show their building potential. The current codes have a prime concern to protect the health and safety of people from the built environment. They have been developed almost exclusively for mainstream industrial materials and methods of construction, which makes them difficult to use with alternative, indigenous, or non-industrial building materials, even though those materials may be considered more sustainable. The argument was put forward that with only one-third of the world population living in modern industrial buildings today, it is not sustainable to re-house the remaining rapidly expanding population in high technology dwellings. Many of the low technology building materials and methods now used by the majority of people in the world need only incremental improvement to be equal or superior to many of their industrial replacements. Since these can be more sustainable methods of building, there needs to be an acceptance of the use of alternative materials, particularly in the developing parts of the world, where they are being rejected for less sustainable industrial methods. However, many codes make it difficult to use non-industrial materials; indeed, many of the industrial materials would not meet the demands that must be now met if they were now being introduced as new materials. Consequently, there is a need to develop codes to facilitate the use of a wider range of materials than in current use, and research is needed to assist this development. Sustainable regulation should take into account the full range of real impacts that materials and systems have in areas such as resource use and

  13. The Structure of Financial Regulation

    OpenAIRE

    Bratu Renate Doina; Petria Nicolae

    2011-01-01

    During the current global financial crisis has called into question the role and objectives of the regulation of financial markets and its scope of action. Liberalization of financial services under the impact of globalization and strong innovative character of the financial system, architecture of regulation has generated a change. In this sense, this paper aims to present and evaluate the structure of financial system regulation in the current international context.

  14. Nitrate Reductase: Properties and Regulation

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Nitrate Reductase (NR) is a rating-limit and key enzyme of nitrate assimilation in plants ,so ,NR activity is important for growth,development and the dry matter accumulation of plants. The regulation of NR activity appears to be rather complex and many studies have been devoted to the description of regulation and properties,but in this paper we focus on the properties and regulation of NR in higher plants.

  15. Regulations on Open Government Information

    Institute of Scientific and Technical Information of China (English)

    YOU XUEYUN

    2007-01-01

    @@ On April 24, 2007 the State Council promulgated Regulations of the People's Republic of China on Open Government Information (referred to as Regulations below), which will become effective on May 1, 2008. As the first administrative rule of the central government of China that aims to safeguard the public's right to know, the Regulations are of great significance in China's democratization and its establishment of the rule of law.

  16. Personality and Emotion Regulation Strategies

    Directory of Open Access Journals (Sweden)

    Esti Hayu Purnamaningsih

    2017-01-01

    Full Text Available The emotions has many important functions in our life such as in relation of interpersonal communication, and health. In interpersonal communicative function aimed to signal to other information about internal state. Emotions manifests in specific cognitive, behavioural, and physiological reactions, thus closely related to health. There is wide variety of ways for individuals to regulate their emotion. In this regard, there are two kinds of emotion regulation strategy; first Antecedent-focused emotion regulation consisting of situation selection, situation modification, attentional deployment, cognitive change and second, Response-focused emotion regulation consisting of suppression. The purpose of this research is to investigate personality factors relate with emotion regulation strategies. 339 students from Faculty of Psychology, Universitas Gadjah Mada were participating in this study and given The Big Five Personality Factors (Ramdhani, 2012, adaptation, and the modified version of the Emotion Regulation Scale was used, Emotion Regulation Questionnaire (John & Gross, 2004 which measure personality and emotion regulation respectively. Using multiple regression analysis, the study indicated that personality predicts emotion regulation strategies.

  17. [Ghrelin: beyond hunger regulation].

    Science.gov (United States)

    Milke García, Maria del Pilar

    2005-01-01

    Man ingests food to mitigate hunger (mediated by physiological and biochemical signals), satisfy appetite (subjective sensation) and because of psychosocial reasons. Satiation biomarkers (stop feeding) are gastric distention and hormones (CCK, GLP-1) and satiety biomarkers (induce feeding) are food-induced thermogenesis, body temperature, glycaemia and also hormones (insulin, leptin and ghrelin). Oxidative metabolism/body composition, tryptophan/serotonin and proinflammatory cytokines are also implicated on hunger physiology. At the present time, ghrelin is the only known circulating orexigenic with potential on hunger/body weight regulation. It is a neuropeptide (endogenous ligand for the GH secretagogue) recently isolated from the oxyntic mucosa and synthesized mainly in the stomach. Its blood concentration depends on diet, hyperglucemia and adiposity/leptin. It is secreted 1-2 hours preprandially and its concentration decreases drastically during the postprandium. Ghrelin acts on the lateral hypothalamus and theoretically inhibits proinflammatory cytokine secretion and antagonizes leptin. Ghrelin physiologically increases food intake and stimulates adipogenesis, gastrointestinal motility and gastric acid secretion, and has other hormonal and cardiovascular functions. Ghrelin blood concentration is reduced in massive obesity, non-alcoholic steatohepatitis, polycystic ovary syndrome, acromegaly, hypogonadism, ageing, short bowel syndrome and rheumatoid arthritis; and increased in primary or secondary anorexia, starvation, chronic liver disease and celiac disease. Cerebral and peritoneal ghrelin administration (rats) and systemic administration (rats and healthy volunteers, cancer patients or patients on peritoneal dialysis) promotes food consumption and increases adiposity, of utmost importance in the treatment of patients with anorexia.

  18. Deciphering Transcriptional Regulation

    DEFF Research Database (Denmark)

    Valen, Eivind

    RNA); and ii) translation, in which the mRNA is translated into a protein. This thesis focus on the ¿rst of these steps, transcription, and speci¿cally the initiation of this. Simpli¿ed, initiation is preceded by the binding of several proteins, known as transcription factors (TFs), to DNA. This takes place......The myriad of cells in the human body are all made from the same blueprint: the human genome. At the heart of this diversity lies the concept of gene regulation, the process in which it is decided which genes are used where and when. Genes do not function as on/off buttons, but more like a volume...... control spanning the range from completely muted to cranked up to maximum. The volume, in this case, is the production rate of proteins. This production is the result of a two step procedure: i) transcription, in which a small part of DNA from the genome (a gene) is transcribed into an RNA molecule (an m...

  19. Regulating the sharing economy

    Directory of Open Access Journals (Sweden)

    Kristofer Erickson

    2016-06-01

    Full Text Available In this introductory essay, we explore definitions of the ‘sharing economy’, a concept indicating both social (relational, communitarian and economic (allocative, profit-seeking aspects which appear to be in tension. We suggest combining the social and economic logics of the sharing economy to focus on the central features of network enabled, aggregated membership in a pool of offers and demands (for goods, services, creative expressions. This definition of the sharing economy distinguishes it from other related peer-to-peer and collaborative forms of production. Understanding the social and economic motivations for and implications of participating in the sharing economy is important to its regulation. Each of the papers in this special issue contributes to knowledge by linking the social and economic aspects of sharing economy practices to regulatory norms and mechanisms. We conclude this essay by suggesting future research to further clarify and render intelligible the sharing economy, not as a contradiction in terms but as an empirically observable realm of socio-economic activity.

  20. Epigenetic regulation in obesity.

    Science.gov (United States)

    Drummond, Elaine M; Gibney, Eileen R

    2013-07-01

    Research suggests that 65% of variation in obesity is genetic. However, much of the known genetic associations have little known function and their effect size small,