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Sample records for cleansing score system

  1. Evaluation of visualized area percentage assessment of cleansing score and computed assessment of cleansing score for capsule endoscopy

    Directory of Open Access Journals (Sweden)

    Chen Hong-Bin

    2013-01-01

    Full Text Available Background/Aim: The purpose of this study was to evaluate the clinical significance of visualized area percentage assessment of cleansing score (AAC and computed assessment of cleansing score (CAC of these two small bowel cleanliness scores systems for capsule endoscopy (CE. Materials and Methods: The reliability and consistency of the AAC and CAC scores were evaluated by comparing the scores by two examiners (one expert, one without any training in CE. Reliability was determined using the intraclass correlation coefficient (ICC and consistency was determined using the kappa statistic. Results: The inter-observer agreement was excellent for both the AAC and CAC scores. For AAC, the ICC was 0.791 (95% confidence interval: 0.677-0.868, and for CAC the ICC was 1.000. Using 1.5 as the cutoff, there was no significant difference between AAC and CAC results by the expert examiner (kappa = 0.756, P = 0.000 or the non-expert examiner (kappa = 0.831, P = 0.000. Evaluation of small bowel cleanliness using AAC took 15-30 min, and evaluation using CAC took about 2-3 min. The overall adequacy assessment (OAA using the AAC was not significantly different between the two examiners (χ2 = 0.586, P = 0.444. There were also no significant differences between the OAA using the AAC and the OAA using the CAC by the expert examiner (χ2 = 1.730, P = 0.188 or the non-expert examiner (χ2 = 1.124, P = 0.289. Conclusion: Both of these scores for assessment of small bowel cleanliness can be useful in clinical practice, but the CAC is simpler to use.

  2. Systems and methods for data quality control and cleansing

    Energy Technology Data Exchange (ETDEWEB)

    Wenzel, Michael; Boettcher, Andrew; Drees, Kirk; Kummer, James

    2016-05-31

    A method for detecting and cleansing suspect building automation system data is shown and described. The method includes using processing electronics to automatically determine which of a plurality of error detectors and which of a plurality of data cleansers to use with building automation system data. The method further includes using processing electronics to automatically detect errors in the data and cleanse the data using a subset of the error detectors and a subset of the cleansers.

  3. Pressurized sewage systems and self-cleansing process

    OpenAIRE

    Popovic, Petar

    2015-01-01

    This master thesis explores the performance of pressurized sewage systems and its effect on self-cleansing of distribution pipes. Pressure sewage systems are mostly applied in non-urban areas where these systems connect and distribute wastewater from household to the main sewage pipeline. The biggest concern for these distribution systems is the possible accumulation of sediments in the sewer pipes, although it is a common phenomenon. The main goal of this thesis is to demonstrate that pre...

  4. Automated load curve data cleansing in power systems

    OpenAIRE

    Chen, Jiyi

    2010-01-01

    Load curve data refers to power consumption recorded by meters at certain time intervals at delivery points or end user points, and contains vital information for day-to-day operations, system analysis, system visualization, system reliability performance, energy saving and adequacy in system planning. It is unavoidable that load curves contain corrupted data and missing data due to various random failure factors in meters and transfer processes. In this thesis, nonparametric smoothing techni...

  5. Comparative efficiency of final endodontic cleansing procedures in removing a radioactive albumin from root canal systems

    International Nuclear Information System (INIS)

    Fifty-six teeth were initially instrumented, with the use of seven irrigants or irrigant combinations, and filled with radioactive albumin. The study then showed the relative ability of three final endodontic procedures (copious reirrigation with saline solution, drying with paper points, and reassuring patency of the canal with the final instrument) to remove the albumin. Even after copious irrigation, each additional procedure removed statistically significant amounts of albumin. Alternating an organic solvent and an inorganic solvent did appear to leave the canal system in the optimal condition for final cleansing procedures. The study then correlated the relative efficiency of irrigation alone versus instrumentation plus irrigation in removing the remaining albumin from the canal systems. Reinstrumentation plus copious irrigation removed significantly more albumin than copious irrigation alone

  6. Volleyball Scoring Systems.

    Science.gov (United States)

    Calhoun, William; Dargahi-Noubary, G. R.; Shi, Yixun

    2002-01-01

    The widespread interest in sports in our culture provides an excellent opportunity to catch students' attention in mathematics and statistics classes. One mathematically interesting aspect of volleyball, which can be used to motivate students, is the scoring system. (MM)

  7. Skin scoring in systemic sclerosis

    DEFF Research Database (Denmark)

    Zachariae, Hugh; Bjerring, Peter; Halkier-Sørensen, Lars;

    1994-01-01

    Forty-one patients with systemic sclerosis were investigated with a new and simple skin score method measuring the degree of thickening and pliability in seven regions together with area involvement in each region. The highest values were, as expected, found in diffuse cutaneous systemic sclerosis...... (type III SS) and the lowest in limited cutaneous systemic sclerosis (type I SS) with no lesions extending above wrists and ancles. A positive correlation was found to the aminoterminal propeptide of type III procollagen, a serological marker for synthesis of type III collagen. The skin score...

  8. Selected aspects of road cleansing in the city of Poznan

    Directory of Open Access Journals (Sweden)

    2010-09-01

    Full Text Available This paper presents issues related to road cleansing in urban areas based on example of the city of Poznan. It describes typical operations in road cleansing and relations with city logistics and green logistics, as well. Road cleansing goals and its influence on transport systems' operations as well as legal framework for functioning of road cleansing in Poland are also presented. The paper includes literature review of decision problems and their solutions leading to improvements of these systems. The author analyses decision problems of similar areas such as road maintenance and transportation, which aims at indicating potential directions of further research.

  9. An evaluation of proximal surface cleansing agents.

    Science.gov (United States)

    Wolffe, G N

    1976-08-01

    The effectiveness of the Interspace brush, Inter-Dens, and waxed dental floss as proximal surface cleansing agents was compared in 35 subjects. Each subject used all three methods of cleansing in random order of selection. Statistical analysis of the results showed that there was no difference in the effectiveness of any one of these three agents. However, proximal surfaces of anterior teeth where cleaned more effectively than posterior teeth. The coronal half of the proximal surfaces was cleaned more effectively than the apical half and the facial half more effectively than the lingual half when Inter-Dens was used. Comparison of cleansing effectiveness between facial and lingual halves of proximal surfaces for the Interspace brush and waxed dental floss showed no significant difference. Mesial and distal proximal surfaces were cleaned with similar effectiveness. Plaque control was only satisfactory on approximately half of the proximal surfaces, though a wide variation occurred. Significantly lower plaque scores were found 1 week after the initial instruction session, irrespective of the agent used. The majority of subjects preferred Inter-Dens whilst waxed dental floss was the least-liked method of cleansing. PMID:1067276

  10. The Efficiency of Tennis Doubles Scoring Systems

    OpenAIRE

    Geoff Pollard; Graham Pollard

    2010-01-01

    In this paper a family of scoring systems for tennis doubles for testing the hypothesis that pair A is better than pair B versus the alternative hypothesis that pair B is better than A, is established. This family or benchmark of scoring systems can be used as a benchmark against which the efficiency of any doubles scoring system can be assessed. Thus, the formula for the efficiency of any doubles scoring system is derived. As in tennis singles, one scoring system based on the play-the-loser ...

  11. THE EFFICIENCY OF TENNIS DOUBLES SCORING SYSTEMS

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    Geoff Pollard

    2010-09-01

    Full Text Available In this paper a family of scoring systems for tennis doubles for testing the hypothesis that pair A is better than pair B versus the alternative hypothesis that pair B is better than A, is established. This family or benchmark of scoring systems can be used as a benchmark against which the efficiency of any doubles scoring system can be assessed. Thus, the formula for the efficiency of any doubles scoring system is derived. As in tennis singles, one scoring system based on the play-the-loser structure is shown to be more efficient than the benchmark systems. An expression for the relative efficiency of two doubles scoring systems is derived. Thus, the relative efficiency of the various scoring systems presently used in doubles can be assessed. The methods of this paper can be extended to a match between two teams of 2, 4, 8, …doubles pairs, so that it is possible to establish a measure for the relative efficiency of the various systems used for tennis contests between teams of players.

  12. Cleansing Formulations That Respect Skin Barrier Integrity

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    Russel M. Walters

    2012-01-01

    Full Text Available Surfactants in skin cleansers interact with the skin in several manners. In addition to the desired benefit of providing skin hygiene, surfactants also extract skin components during cleansing and remain in the stratum corneum (SC after rinsing. These side effects disrupt SC structure and degrade its barrier properties. Recent applications of vibrational spectroscopy and two-photon microscopy in skin research have provided molecular-level information to facilitate our understanding of the interaction between skin and surfactant. In the arena of commercial skin cleansers, technologies have been developed to produce cleansers that both cleanse and respect skin barrier. The main approach is to minimize surfactant interaction with skin through altering its solution properties. Recently, hydrophobically modified polymers (HMPs have been introduced to create skin compatible cleansing systems. At the presence of HMP, surfactants assemble into larger, more stable structures. These structures are less likely to penetrate the skin, thereby resulting in less aggressive cleansers and the integrity of the skin barrier is maintained. In this paper, we reviewed our recent findings on surfactant and SC interactions at molecular level and provided an overview of the HM technology for developing cleansers that respect skin barrier.

  13. Formation and cleansing performance of bicontinuous microemulsions in water/poly (oxyethylene) alkyl ether/ester-type oil systems.

    Science.gov (United States)

    Aramaki, Kenji; Tawa, Kosuke; Shrestha, Lok Kumar; Iwanaga, Tetsuro; Kamada, Miho

    2013-01-01

    Phase behaviors in water/poly(oxyethylene) dodecyl ether (C₁₂EO(n), n = 4, 6, 8)/cetyl isooctanoate (CIO) systems were studied. In the C₁₂EO₆ and C₁₂EO₈ systems, self-assembled structures with positive curvatures, such as O/W microemulsions, and micellar cubic and hexagonal phases, were observed. A wider region of a lamellar liquid-crystalline phase, which included a narrow microemulsion region joined by a miscibility gap, was observed in the C₁₂EO₄ system. The structure of the microemulsion phase in the C₁₂EO₄ system was characterized by pulsed-field-gradient NMR (PFG-NMR) and small angle X-ray scattering (SAXS) techniques. PFG-NMR measurements indicated that the structure of the microemulsion was bicontinuous; both water and oil phases were continuous within the microemulsion. Pair-distance distribution function, p (r), and structure factors obtained by Generalized Indirect Fourier Transformation (GIFT) analysis of the SAXS data showed that the microemulsion domain sizes decreased with an increase in the oil content. The structure of the bicontinuous microemulsion was consistent with the results of a detergency test, in which the microemulsion samples were applied to lipstick dirt on an artificial skin plate. Detergency was observed to be better for the microemulsion at lower oil contents because of the larger oil domain size at these low concentrations. PMID:24088518

  14. Spacecraft utensil/hand cleansing fixture

    Science.gov (United States)

    Jonkoniec, T. G.

    1978-01-01

    A fixture which provides a means for a crewman to perform, in zero gravity, laboratory utensil/tool cleansing and personal hygiene functions such as handwashing, shaving, body wash, and teeth brushing is described. A prototype unit developed incorporating design improvements resulting from breadboard tests in a one gravity and zero gravity environment demonstrated the capability of performing the different cleansing functions.

  15. Relational-Based Sensor Data Cleansing

    DEFF Research Database (Denmark)

    Iftikhar, Nadeem; Liu, Xiufeng; Nordbjerg, Finn Ebertsen

    2015-01-01

    Today sensors are widely used in many monitoring applications. Due to some random environmental effects and/or sensing failures, the collected sensor data is typically noisy. Thus, it is critical to cleanse the sensor data before using it to answer queries or conduct data analysis. Popular data...... cleansing approaches, such as classification, prediction and moving average are not suited for embedded sensor devices, due to the limited storage and processing capabilities. In this paper, we propose a sensor data cleansing approach using the relational-based technologies, including constraints, triggers...

  16. Supersparse Linear Integer Models for Predictive Scoring Systems

    OpenAIRE

    Ustun, Berk; Traca, Stefano; Rudin, Cynthia

    2013-01-01

    We introduce Supersparse Linear Integer Models (SLIM) as a tool to create scoring systems for binary classification. We derive theoretical bounds on the true risk of SLIM scoring systems, and present experimental results to show that SLIM scoring systems are accurate, sparse, and interpretable classification models.

  17. Clinical significance of scoring system for systemic inflammatory response syndrome

    Institute of Scientific and Technical Information of China (English)

    HAN Jian; LIANG Hua-ping

    2006-01-01

    The concepts of systemic inflammatory response syndrome (SIRS) and scoring system were defined by the journal of Bone in 1992. SIRS was described as occurrence of two or more clinical criteria in four ones (fever or hypothermia, tachypnea, tachycardia, and leukocytosis).An early diagnosis and estimation of systemic inflammation in patients is helpful for treatment selection. This paper reviews the application of SIRS scoring system, which has been extensively validated for large groups of critical care patients with severe injury and critical surgical diseases.Recent studies have documented SIRS score as a significant predictive parameter of adverse outcome in critical care patients. Furthermore, some studies also give us a suggestion on how to reduce the overload systemic response.

  18. Relational-Based Sensor Data Cleansing

    DEFF Research Database (Denmark)

    Iftikhar, Nadeem; Liu, Xiufeng; Nordbjerg, Finn Ebertsen

    2015-01-01

    cleansing approaches, such as classification, prediction and moving average are not suited for embedded sensor devices, due to the limited storage and processing capabilities. In this paper, we propose a sensor data cleansing approach using the relational-based technologies, including constraints, triggers...... and granularity-based data aggregation. The proposed approach is simple but effective to cleanse different types of dirty data, including delayed data, incomplete data, incorrect data, duplicate data and missing data. We evaluate the proposed strategy to verify its efficiency, effectiveness and......Today sensors are widely used in many monitoring applications. Due to some random environmental effects and/or sensing failures, the collected sensor data is typically noisy. Thus, it is critical to cleanse the sensor data before using it to answer queries or conduct data analysis. Popular data...

  19. Validation of a new scoring system: Rapid assessment faecal incontinence score

    Institute of Scientific and Technical Information of China (English)

    Fernando; de; la; Portilla; Arantxa; Calero-Lillo; Rosa; M; Jiménez-Rodríguez; Maria; L; Reyes; Manuela; Segovia-González; María; Victoria; Maestre; Ana; M; García-Cabrera

    2015-01-01

    AIM: To implement a quick and simple test- rapid assessment faecal incontinence score(RAFIS) and show its reliability and validity.METHODS: From March 2008 through March 2010, we evaluated a total of 261 consecutive patients, including 53 patients with faecal incontinence. Demographic and comorbidity information was collected. In a single visit, patients were administered the RAFIS. The results obtained with the new score were compared with those of both Wexner score and faecal incontinence quality of life scale(FIQL) questionnaire. The patient withoutinfluence of the surgeon completed the test. The role of surgeon was explaining the meaning of each section and how he had to fill. Reliability of the RAFIS score was measured using intra-observer agreement and Cronbach’s alpha(internal consistency) coefficient. Multivariate analysis of the main components within the different scores was performed in order to determine whether all the scores measured the same factor and to conclude whether the information could be encompassed in a single factor. A sample size of 50 patients with faecal incontinence was estimated to be enough to detect a correlation of 0.55 or better at 5% level of significance with 80% power.RESULTS: We analysed the results obtained by 53 consecutive patients with faecal incontinence(median age 61.55 ± 12.49 years) in the three scoring systems. A total of 208 healthy volunteers(median age 58.41 ± 18.41 years) without faecal incontinence were included in the study as negative controls. Pearson’s correlation coefficient between "state" and "leaks" was excellent(r = 0.92, P < 0.005). Internal consistency in the comparison of "state" and "leaks" yielded also excellent correlation(Cronbach’s α = 0.93). Results in each score were compared using regression analysis and a correlation value of r = 0.98 was obtained with Wexner score. As regards FIQL questionnaire, the values of "r " for the different subscales of the questionnaire were: "lifestyle" r

  20. Jet Cleansing: Pileup Removal at High Luminosity

    CERN Document Server

    Krohn, David; Schwartz, Matthew D; Wang, Lian-Tao

    2013-01-01

    One of the greatest impediments to extracting useful information from high luminosity hadron-collider data is radiation from secondary collisions (i.e. pileup) which can overlap with that of the primary interaction. In this paper we introduce a simple jet-substructure technique termed cleansing which can consistently correct for large amounts of pileup in an observable independent way. Cleansing works at the subjet level, combining tracker and calorimeter-based data to reconstruct the pileup-free primary interaction. The technique can be used on its own, with various degrees of sophistication, or in concert with jet grooming. We apply cleansing to both kinematic and jet shape reconstruction, finding in all cases a marked improvement over previous methods both in the correlation of the cleansed data with uncontaminated results and in measures like S/rt(B). Cleansing should improve the sensitivity of new-physics searches at high luminosity and could also aid in the comparison of precision QCD calculations to co...

  1. Small bowel cleansing does not improve quality of wireless capsule endoscopy

    DEFF Research Database (Denmark)

    Wilkens, Rune; Langholz, Ebbe; Glerup, Henning

    increasing demand of early diagnosis, WCE becomes more important. However, a drawback is the limited visualization of the mucosa in patients with poor cleansing quality. The aim of our study was to determine the benefit of preparation with Picoprep prior to examination with WCE and evaluate two different...... by Park et al. 2010 [2] with a 3 grade subjective assessment every 5 minutes and Weyenberg et al. 2011 [3] with a computer assessment of cleansing using the colour bar in the capsule reading software. Mean overall score between groups were compared using students ttest. Results We enrolled 135...

  2. Scoring systems for predicting mortality after liver transplantation.

    Directory of Open Access Journals (Sweden)

    Heng-Chih Pan

    Full Text Available BACKGROUND: Liver transplantation can prolong survival in patients with end-stage liver disease. We have proposed that the Sequential Organ Failure Assessment (SOFA score calculated on post-transplant day 7 has a great discriminative power for predicting 1-year mortality after liver transplantation. The Chronic Liver Failure-Sequential Organ Failure Assessment (CLIF-SOFA score, a modified SOFA score, is a newly developed scoring system exclusively for patients with end-stage liver disease. This study was designed to compare the CLIF-SOFA score with other main scoring systems in outcome prediction for liver transplant patients. METHODS: We retrospectively reviewed medical records of 323 patients who had received liver transplants in a tertiary care university hospital from October 2002 to December 2010. Demographic parameters and clinical characteristic variables were recorded on the first day of admission before transplantation and on post-transplantation days 1, 3, 7, and 14. RESULTS: The overall 1-year survival rate was 78.3% (253/323. Liver diseases were mostly attributed to hepatitis B virus infection (34%. The CLIF-SOFA score had better discriminatory power than the Child-Pugh points, Model for End-Stage Liver Disease (MELD score, RIFLE (risk of renal dysfunction, injury to the kidney, failure of the kidney, loss of kidney function, and end-stage kidney disease criteria, and SOFA score. The AUROC curves were highest for CLIF-SOFA score on post-liver transplant day 7 for predicting 1-year mortality. The cumulative survival rates differed significantly for patients with a CLIF-SOFA score ≤8 and those with a CLIF-SOFA score >8 on post-liver transplant day 7. CONCLUSION: The CLIF-SOFA score can increase the prediction accuracy of prognosis after transplantation. Moreover, the CLIF-SOFA score on post-transplantation day 7 had the best discriminative power for predicting 1-year mortality after liver transplantation.

  3. [Validation of a diagnostic scoring system (Ohmann score) in acute appendicitis].

    Science.gov (United States)

    Zielke, A; Sitter, H; Rampp, T A; Schäfer, E; Hasse, C; Lorenz, W; Rothmund, M

    1999-07-01

    A diagnostic scoring system, recently published by Ohmann et al. in this journal, was validated by analyzing the clinicopathological data of a consecutive series of 2,359 patients, admitted for suspicion of acute appendicitis. The results of the scoring system were compared to the results of clinical evaluation by junior (provisional) and senior surgeons (final clinical diagnosis). To assess the diagnostic ability of the score, the accuracy and positive predictive value were defined as the major diagnostic performance parameters; the rate of theoretical negative laparotomies and that of diagnostic errors served as the major procedural performance parameters. Of 2,359 patients admitted for suspected acute appendicitis, 662 were proven to have acute appendicitis by histology, for a prevalence of 28%. The overall sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of the provisional clinical diagnosis were 0.50, 0.94, 0.77, 0.83, and 0.82; 0.93, for the score 0.63, 0.93, 0.77, 0.86 and 0.84, and for the final clinical diagnosis 0.90, 0.94, 0.85, 0.96, and 0.93, respectively. Of the main diagnostic performance parameter, the accuracy of the score was significantly better than that of provisional clinical diagnosis (P apendicitis, the score demonstrated a superior performance, with only 6 cases missed (0.9%). However, the number of patients with acute appendicitis, including those with perforated disease, who were not identified by the score, was almost four times that of the final clinical diagnosis (245 vs 63). With regard to the main procedural performance parameter, the score resulted in a significantly smaller number of diagnostic errors than the provisional clinical investigator (P < 0.05, chi 2 test). The results of this study indicate that the diagnostic scoring system might be helpful when experienced investigators or additional diagnostic modalities such as ultrasonography are not available. It may therefore be of value

  4. Symptom scoring systems to diagnose distal polyneuropathy in diabetes : the Diabetic Neuropathy Symptom score

    NARCIS (Netherlands)

    Meijer, J.W.G.; Smit, A.J.; van Sonderen, E.; Groothoff, J.W.; Eisma, W.H.; Links, T.P.

    2002-01-01

    AIMS: To provide one of the diagnostic categories for distal diabetic polyneuro-pathy,several symptom scoring systems are available, which are often extensive andlack in validation. We validated a new four-item Diabetic Neuropathy Symptom (DNS) scorefor diagnosing distal diabetic polyneuropathy. MET

  5. Uncovering Concerns with Developing a Scoring System at ETS.

    Science.gov (United States)

    Stires, Susan

    1995-01-01

    Describes an expert panel member's experiences in working with Educational Testing Service to redesign the scoring for the National Board for Professional Teaching Standards Early Adolescence/English Language Arts Assessment. Maintains that a less mechanistic and more valid scoring system could have been developed if criticism and open discussion…

  6. Evaluation of prognostic factors and scoring system in colonic perforation

    Institute of Scientific and Technical Information of China (English)

    Atsushi Horiuchi; Yuji Watanabe; Takashi Doi; Kouichi Sato; Syungo Yukumi; Motohira Yoshida; Yuji Yamamoto; Hiroki Sugishita; Kanji Kawachi

    2007-01-01

    AIM: To study the significance of scoring systems assessing severity and prognostic factors in patients with colonic perforation.METHODS: A total of 26 patients (9 men, 17 women;mean age 72.7±11.6 years) underwent emergency operation for colorectal perforation in our institution between 1993 and 2005. Several clinical factors were measured preoperatively and 24 h postoperatively. Acute physiology and chronic health evaluationⅡ (APACHE Ⅱ),Mannheim peritonitis index (MPI) and peritonitis index of Altona (PIA Ⅱ) scores were calculated preoperatively.RESULTS: Overall postoperative mortality rate was 23.1% (6 patients). Compared with survivors, nonsurvivors displayed low blood pressure, low serum protein and high serum creatinine preoperatively, and low blood pressure, low white blood cell count, low pH,low PaO2/FiO2, and high serum creatinine postoperatively.APACHE Ⅱ score was significantly lower in survivors than in non-survivors (10.4±3.84 vs19.3±2.87, P= 0.00003). Non-survivors tended to display high MPI score and low PIA Ⅱ score, but no significant difference was identified.CONCLUSION: Pre- and postoperative blood pressure and serum creatinine level appear related to prognosis of colonic perforation. APACHE Ⅱ score is most associated with prognosis and scores ≥ 20 are associated with significantly increased mortality rate.

  7. Stroke Risk Predictor Scoring Systems in Atrial Fibrillation

    Directory of Open Access Journals (Sweden)

    Tze-Fan Chao, M.D; Shih-Ann Chen, M.D.

    2014-02-01

    Full Text Available An effective risk stratification which could help us identify high-risk patients who should take oral anticoagulants (OACs is the key step for stroke prevention in atrial fibrillation (AF. Several scoring systems were available to estimate the risk of stroke in AF, including CHADS2, CHA2DS2-VASc, R2CHADS2 and ATRIA scores, which were constituted of different clinical risk factors. Recently, several new OACs (NOACs were demonstrated to be at least as effective as warfarin in stroke prevention and were much safer regarding the risk of intra-cranial hemorrhage. In the era of NOACs, the roles of scoring schemes have shifted to identify patinets with a truly low-risk of thromboembolic events, in whom OACs were not recommended. The CHA2DS2-VASc score is powerful in selecting “truly low-risk” patients who are not necessary to receive anticoagulation therapies. Whether the new-emerging scoring systems, R2CHADS2 and ATRIA scores, could further improve the stroke prediction in AF deserves a further study.

  8. Disease scoring systems for oral lichen planus; a critical appraisal

    NARCIS (Netherlands)

    J. Wang; I. van der Waal

    2015-01-01

    The aim of the present study has been to critically review 22 disease scoring systems (DSSs) on oral lichen planus (OLP) that have been reported in the literature during the past decades. Although the presently available DSSs may all have some merit, particularly for research purposes, the diversity

  9. Calixarene cleansing formulation for uranium skin contamination.

    Science.gov (United States)

    Phan, Guillaume; Semili, Naïma; Bouvier-Capely, Céline; Landon, Géraldine; Mekhloufi, Ghozlene; Huang, Nicolas; Rebière, François; Agarande, Michelle; Fattal, Elias

    2013-10-01

    An oil-in-water cleansing emulsion containing calixarene molecule, an actinide specific chelating agent, was formulated in order to improve the decontamination of uranium from the skin. Commonly commercialized cosmetic ingredients such as surfactants, mineral oil, or viscosifying agents were used in preparing the calixarene emulsion. The formulation was characterized in terms of size and apparent viscosity measurements and then was tested for its ability to limit uranyl ion permeation through excoriated pig-ear skin explants in 24-h penetration studies. Calixarene emulsion effectiveness was compared with two other reference treatments consisting of DTPA and EHBP solutions. Application of calixarene emulsion induced the highest decontamination effect with an 87% decrease in uranium diffusion flux. By contrast, EHBP and DTPA solutions only allowed a 50% and 55% reduction of uranium permeation, respectively, and had the same effect as a simple dilution of the contamination by pure water. Uranium diffusion decrease was attributed to uranyl ion-specific chelation by calixarene within the formulation, since no significant effect was obtained after application of the same emulsion without calixarene. Thus, calixarene cleansing emulsion could be considered as a promising treatment in case of accidental contamination of the skin by highly diffusible uranium compounds. PMID:23982616

  10. A new scoring system to stratify risk in unstable angina

    Directory of Open Access Journals (Sweden)

    Salzberg Simón

    2003-08-01

    Full Text Available Abstract Background We performed this study to develop a new scoring system to stratify different levels of risk in patients admitted to hospital with a diagnosis of unstable angina (UA, which is a complex syndrome that encompasses different outcomes. Many prognostic variables have been described but few efforts have been made to group them in order to enhance their individual predictive power. Methods In a first phase, 473 patients were prospectively analyzed to determine which factors were significantly associated with the in-hospital occurrence of refractory ischemia, acute myocardial infarction (AMI or death. A risk score ranging from 0 to 10 points was developed using a multivariate analysis. In a second phase, such score was validated in a new sample of 242 patients and it was finally applied to the entire population (n = 715. Results ST-segment deviation on the electrocardiogram, age ≥ 70 years, previous bypass surgery and troponin T ≥ 0.1 ng/mL were found as independent prognostic variables. A clear distinction was shown among categories of low, intermediate and high risk, defined according to the risk score. The incidence of the triple end-point was 6 %, 19.2 % and 44.7 % respectively, and the figures for AMI or death were 2 %, 11.4 % and 27.6 % respectively (p Conclusions This new scoring system is simple and easy to achieve. It allows a very good stratification of risk in patients having a clinical diagnosis of UA. They may be divided in three categories, which could be of help in the decision-making process.

  11. A risk scoring system for prediction of haemorrhagic stroke.

    Science.gov (United States)

    Zodpey, S P; Tiwari, R R

    2005-01-01

    The present pair-matched case control study was carried out at Government Medical College Hospital, Nagpur, India, a tertiary care hospital with the objective to devise and validate a risk scoring system for prediction of hemorrhagic stroke. The study consisted of 166 hospitalized CT scan proved cases of hemorrhagic stroke (ICD 9, 431-432), and a age and sex matched control per case. The controls were selected from patients who attended the study hospital for conditions other than stroke. On conditional multiple logistic regression five risk factors- hypertension (OR = 1.9. 95% Cl = 1.5-2.5). raised scrum total cholesterol (OR = 2.3, 95% Cl = 1.1-4.9). use of anticoagulants and antiplatelet agents (OR = 3.4, 95% Cl =1.1-10.4). past history of transient ischaemic attack (OR = 8.4, 95% Cl = 2.1- 33.6) and alcohol intake (OR = 2.1, 95% Cl = 1.3-3.6) were significant. These factors were ascribed statistical weights (based on regression coefficients) of 6, 8, 12, 21 and 8 respectively. The nonsignificant factors (diabetes mellitus, physical inactivity, obesity, smoking, type A personality, history of claudication, family history of stroke, history of cardiac diseases and oral contraceptive use in females) were not included in the development of scoring system. ROC curve suggested a total score of 21 to be the best cut-off for predicting haemorrhag stroke. At this cut-off the sensitivity, specificity, positive predictivity and Cohen's kappa were 0.74, 0.74, 0.74 and 0.48 respectively. The overall predictive accuracy of this additive risk scoring system (area under ROC curve by Wilcoxon statistic) was 0.79 (95% Cl = 0.73-0.84). Thus to conclude, if substantiated by further validation, this scorincy system can be used to predict haemorrhagic stroke, thereby helping to devise effective risk factor intervention strategy. PMID:16479901

  12. A credit score system for socially responsible lending

    OpenAIRE

    Gutiérrez-Nieto, Begoña; Serrano-Cinca, Carlos; Camón-Cala, Juan

    2011-01-01

    Ethical banking, microfinance institutions or certain credit cooperatives, among others, grant socially responsible loans. This paper presents a credit score system for them. The model evaluates both social and financial aspects of the borrower. The financial aspects are evaluated under the conventional banking framework, by analysing accounting statements and financial projections. The social aspects try to quantify the loan impact on the achievement of Millennium Development Goals such as e...

  13. Reliability of clinician scoring of the landing error scoring system to assess jump-landing movement patterns.

    Science.gov (United States)

    Markbreiter, Jessica G; Sagon, Bronson K; Valovich McLeod, Tamara C; Welch, Cailee E

    2015-05-01

    Clinical Scenario: An individual's movement patterns while landing from a jump can predispose him or her to lower-extremity injury, if performed improperly. The Landing Error Scoring System (LESS) is a clinical tool to assess jump-landing biomechanics as an individual jumps forward from a box. Improper movement patterns, which could predispose an individual to lower-extremity injuries, are scored as errors. However, because of the subjective nature of scoring errors during the task, the consistency and reliability of scoring the task are important. Since the LESS is a newer assessment tool, it is important to understand its reliability. Focused Clinical Question: Are clinicians reliable at scoring the LESS to assess jump-landing biomechanics of physically active individuals? PMID:25203628

  14. Description and validation of a scoring system for tomosynthesis in pulmonary cystic fibrosis

    Energy Technology Data Exchange (ETDEWEB)

    Vult von Steyern, Kristina; Bjoerkman-Burtscher, Isabella M.; Bozovic, Gracijela; Wiklund, Marie; Geijer, Mats [Skaane University Hospital, Lund University, Centre for Medical Imaging and Physiology, Lund (Sweden); Hoeglund, Peter [Skaane University Hospital, Competence Centre for Clinical Research, Lund (Sweden)

    2012-12-15

    To design and validate a scoring system for tomosynthesis (digital tomography) in pulmonary cystic fibrosis. A scoring system dedicated to tomosynthesis in pulmonary cystic fibrosis was designed. Three radiologists independently scored 88 pairs of radiographs and tomosynthesis examinations of the chest in 60 patients with cystic fibrosis and 7 oncology patients. Radiographs were scored according to the Brasfield scoring system and tomosynthesis examinations were scored using the new scoring system. Observer agreements for the tomosynthesis score were almost perfect for the total score with square-weighted kappa >0.90, and generally substantial to almost perfect for subscores. Correlation between the tomosynthesis score and the Brasfield score was good for the three observers (Kendall's rank correlation tau 0.68, 0.77 and 0.78). Tomosynthesis was generally scored higher as a percentage of the maximum score. Observer agreements for the total score for Brasfield score were almost perfect (square-weighted kappa 0.80, 0.81 and 0.85). The tomosynthesis scoring system seems robust and correlates well with the Brasfield score. Compared with radiography, tomosynthesis is more sensitive to cystic fibrosis changes, especially bronchiectasis and mucus plugging, and the new tomosynthesis scoring system offers the possibility of more detailed and accurate scoring of disease severity. (orig.)

  15. Description and validation of a scoring system for tomosynthesis in pulmonary cystic fibrosis

    International Nuclear Information System (INIS)

    To design and validate a scoring system for tomosynthesis (digital tomography) in pulmonary cystic fibrosis. A scoring system dedicated to tomosynthesis in pulmonary cystic fibrosis was designed. Three radiologists independently scored 88 pairs of radiographs and tomosynthesis examinations of the chest in 60 patients with cystic fibrosis and 7 oncology patients. Radiographs were scored according to the Brasfield scoring system and tomosynthesis examinations were scored using the new scoring system. Observer agreements for the tomosynthesis score were almost perfect for the total score with square-weighted kappa >0.90, and generally substantial to almost perfect for subscores. Correlation between the tomosynthesis score and the Brasfield score was good for the three observers (Kendall's rank correlation tau 0.68, 0.77 and 0.78). Tomosynthesis was generally scored higher as a percentage of the maximum score. Observer agreements for the total score for Brasfield score were almost perfect (square-weighted kappa 0.80, 0.81 and 0.85). The tomosynthesis scoring system seems robust and correlates well with the Brasfield score. Compared with radiography, tomosynthesis is more sensitive to cystic fibrosis changes, especially bronchiectasis and mucus plugging, and the new tomosynthesis scoring system offers the possibility of more detailed and accurate scoring of disease severity. (orig.)

  16. Comparison of AIMS65 Score and Other Scoring Systems for Predicting Clinical Outcomes in Koreans with Nonvariceal Upper Gastrointestinal Bleeding

    Science.gov (United States)

    Park, Sung Min; Yeum, Seok Cheon; Kim, Byung-Wook; Kim, Joon Sung; Kim, Ji Hee; Sim, Eun Hui; Ji, Jeong-Seon; Choi, Hwang

    2016-01-01

    Background/Aims The AIMS65 score has not been sufficiently validated in Korea. The objective of this study was to compare the AIMS65 and other scoring systems for the prediction of various clinical outcomes in Korean patients with acute nonvariceal upper gastrointestinal bleeding (NVUGIB). Methods The AIMS65 score, clinical and full Rockall scores (cRS and fRS) and Glasgow-Blatchford (GBS) score were calculated in patients with NVUGIB in a single center retrospectively. The performance of these scores for predicting mortality, rebleeding, transfusion requirement, and endoscopic intervention was assessed by calculating the area under the receiver-operating characteristic curve. Results Of the 523 patients, 3.4% died within 30 days, 2.5% experienced rebleeding, 40.0% required endoscopic intervention, and 75.7% needed transfusion. The AIMS65 score was useful for predicting the 30-day mortality, the need for endoscopic intervention and for transfusion. The fRS was superior to the AIMS65, GBS, and cRS for predicting endoscopic intervention and the GBS was superior to the AIMS65, fRS, and cRS for predicting the transfusion requirement. Conclusions The AIMS65 score was useful for predicting the 30-day mortality, transfusion requirement, and endoscopic intervention in Korean patients with acute NVUGIB. However, it was inferior to the GBS and fRS for predicting the transfusion requirement and endoscopic intervention, respectively. PMID:27377742

  17. Development of an automated scoring system for plant comet assay

    Directory of Open Access Journals (Sweden)

    Bertrand Pourrut

    2015-05-01

    -\tnucleus density: increase the density of nuclei is of importance to increase scoring reliability (Sharma et al., 2012. In conclusion, increasing plant nucleus extraction yield and automated scoring of nuclei do represent big challenges. However, our promising preliminary results open up the perspective of an automated high-throughput scoring of plant nuclei.

  18. Description and validation of a scoring system for tomosynthesis in pulmonary cystic fibrosis.

    OpenAIRE

    Vult von Steyern, Kristina; Björkman-Burtscher, Isabella; Höglund, Peter; Bozovic, Gracijela; Wiklund, Marie; Geijer, Mats

    2012-01-01

    OBJECTIVES: To design and validate a scoring system for tomosynthesis (digital tomography) in pulmonary cystic fibrosis. METHODS: A scoring system dedicated to tomosynthesis in pulmonary cystic fibrosis was designed. Three radiologists independently scored 88 pairs of radiographs and tomosynthesis examinations of the chest in 60 patients with cystic fibrosis and 7 oncology patients. Radiographs were scored according to the Brasfield scoring system and tomosynthesis examination...

  19. Natural history of alkaptonuria revisited: analyses based on scoring systems.

    Science.gov (United States)

    Ranganath, Lakshminarayan R; Cox, Trevor F

    2011-12-01

    Increased circulating homogentisic acid in body fluids occurs in alkaptonuria (AKU) due to lack of enzyme homogentisate dioxygenase leading in turn to conversion of HGA to a pigmented melanin-like polymer, known as ochronosis. The tissue damage in AKU is due to ochronosis. A potential treatment, a drug called nitisinone, to decrease formation of HGA is available. However, deploying nitisinone effectively requires its administration at the most optimal time in the natural history. AKU has a long apparent latent period before overt ochronosis develops. The rate of change of ochronosis and its consequences over time following its recognition has not been fully described in any quantitative manner. Two potential tools are described that were used to quantitate disease burden in AKU. One tool describes scoring the clinical features that includes clinical assessments, investigations and questionnaires in 15 patients with AKU. The second tool describes a scoring system that only includes items obtained from questionnaires in 44 people with AKU. Analysis of the data reveals distinct phases of the disease, a pre-ochronotic phase and an ochronotic phase. The ochronotic phase appears to demonstrate an earlier slower progression followed by a rapidly progressive phase. The rate of change of the disease will have implications for monitoring the course of the disease as well as decide on the most appropriate time that treatment should be started for it to be effective either in prevention or arrest of the disease. PMID:21748407

  20. Head-to-head comparison of quantitative and semi-quantitative ultrasound scoring systems for rheumatoid arthritis

    DEFF Research Database (Denmark)

    Terslev, Lene; Ellegaard, Karen; Christensen, Robin;

    2012-01-01

    To evaluate the reliability and agreement of semi-quantitative scoring (SQS) and quantitative scoring (QS) systems. To compare the two types of scoring system and investigate the construct validity for both scoring systems....

  1. Apgar Scores

    Science.gov (United States)

    ... are more likely to have low scores than infants with normal births. These scores may reflect difficulties the baby experienced during labor or problems with her heart or respiratory system. What if Your Baby Scores Low? If your ...

  2. Implementation of the new solid waste management and public cleansing act-The way forward

    International Nuclear Information System (INIS)

    In Malaysia, Act 672 are one act that mention on Public Cleansing Managements Services and Solid Waste Management. Scope of Public Cleansing Managements Services included public places, public drains, public toilets, public hawker centers, public markets and so on. These act also mentioned about recycling, control of solid waste, enforcement provision, and assumption of control, tribunal, charges, licensing and many more. So, for the implementation, we have collecting households waste, licensing collectors for all categories of solid waste, improving Solid Waste Management facilities and others. We can monitor the concession using hand held system. Through this systems, we recorded evidence of defaults, then we upload the data, after that, we determine the penalty for each scheme area and then we report the generation. All of these was doing in order to make sure all the Malaysian citizens obey the rules and to make sure there is no abuse on these issues. Fortunately, these can increase our environment safe and sustained forever.

  3. Hemophilic arthropathy. A scoring system for magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Soler, R.; Rodriguez, E.; Marini, M. [Department of Radiology, Hospital Juan Canalejo, Coruna (Spain); Lopez-Fernandez, F. [Department of Hematology, Hospital Juan Canalejo, Coruna (Spain)

    2002-04-01

    The aim of this study was to define a system for scoring hemophilic arthropathy (HA) based on MR findings, providing for objective evaluation of the degree of joint involvement and evolution after on-demand administration of FVIII substitutional therapy or prophylactic treatment. A total of 133 MR examinations (89 basal and 44 during follow-up) were performed in 25 patients. Patients were divided in two groups depending on the therapy received and the length of time that the disease had been evolving at the start of the study. Group I was composed of 10 patients with secondary prophylaxis and group II was composed by 15 treated on demand. T1-weighted and T2*-weighted images performed on a 0.5-T unit were prospectively evaluated. The joint involvement was established on a scale of 0 (no abnormalities), I (minimal amount of hemosiderin), II (large amount of hemosiderin and isolated cartilaginous erosion), III (cartilage destruction, bone erosions, and subchondral cysts) to IV (large internal joint derangement, secondary osteoarthritis and/or ankylosis). At basal MR examination, patients of group I showed no abnormalities (n=28, 75.6%), grade I (n=3), and grade II (n=6) of HA. Patients of group II corresponded to MR grades III (n=21) and IV (n=11) of HA. The MR follow-up showed improvement in three joints of group I and worsening in 5 joints in group I and 2 joints in group II. Early signs of HA were detected in 10 joints with MR imaging but were underestimated on plain radiographs. Advanced degrees of HA were classified as severe under both imaging techniques. Magnetic resonance is the preferred imaging technique to assess HA. The earliest signs of joint damage, detected by MR, are overlooked by plain radiography. The MR scoring system can be used for evaluating HA. Follow-up MR should be performed to evaluate regression or worsening of the abnormalities, primarily in the case of patients with prophylaxis who usually suffer normal or early joint involvement not

  4. Prognostic factors and scoring system for death from visceral leishmaniasis: an historical cohort study in Brazil.

    Directory of Open Access Journals (Sweden)

    Wendel Coura-Vital

    2014-12-01

    Full Text Available In Brazil, case-fatality rates attributable to visceral leishmaniasis (VL are high and knowledge of the risk factors associated with death may help reduce mortality. The aim of this study was to construct and validate a scoring system for prognosis of death from VL by using all cases reported in Brazil from 2007 to 2011.In this historical cohort study, 18,501 VL cases were analyzed; of these, 17,345 cases were cured and 1,156 cases caused death. The database was divided into two series: primary (two-thirds of cases, to develop the model score, and secondary (one-third of cases, to validate the scoring system. Multivariate logistic regression models were performed to identify factors associated with death from VL, and these were included in the scoring system.The factors associated with death from VL were: bleeding (score 3; splenomegaly (score 1; edema (score 1; weakness (score 1; jaundice (score 1; Leishmania-HIV co-infection (score 1; bacterial infection (score 1; and age (≤0.5 years [score 5]; >0.5 and ≤1 [score 2]; >19 and ≤50 [score 2]; >50 and <65 [score 3]; ≥65 [score 5]. It was observed that patients with a score of 4 had a probability of death of approximately 4.5% and had a worse prognosis. The sensitivity, specificity, and accuracy of this score were 89.4, 51.2, and 53.5, respectively.The scoring system based on risk factors for death showed good performance in identifying patients with signs of severity at the time of clinical suspicion of VL and can contribute to improving the surveillance system for reducing case fatalities. The classification of patients according to their prognosis for death may assist decision-making regarding the transfer of the patients to hospitals more capable of handling their condition, admission to the intensive care unit, and adequate support and specific treatment.

  5. Utility of prognostic scoring systems for colorectal liver metastases in an era of advanced multimodal therapy

    OpenAIRE

    E. Gregoire; Hoti, E.; Gorden, D.L.; Pascal, G.; Azoulay, D

    2010-01-01

    Abstract Objectives To assess the general applicability of prognostic scores for colorectal liver metastases (CRLM). Methods Review of English language studies from 1980 to 2008 (Medline and Embase). Search keywords included ?Colorectal neoplasms?, ?liver metastases?, ?liver resection?, ?prognostic scoring system?. Results Six scoring systems and fourteen prognostic factors within these studies were identified. No prognostic fa...

  6. Toothbrushes with graduated wear: correlation with in vitro cleansing performance.

    Science.gov (United States)

    Dean, D H

    1991-01-01

    A display set of toothbrushes with graduated natural wear was shown to 268 adult respondents who were asked to indicate which brushes were "worn out." The same brushes were then compared against each other for their ability to remove artificial plaque in models of interproximal and facial surface cleansing effectiveness. Despite pronounced differences in the degree of wear among the toothbrushes, no correlation was found between visual estimation of toothbrush effectiveness and its cleansing ability in the models tested. It is possible that other variables (toothbrushing technique, force applied, manual skills) exert a greater influence on plaque removal than brush wear and explain the results of this experiment. PMID:1884573

  7. Burn Wound Cleansing - A Myth or a Scientific Practice

    OpenAIRE

    Hayek, S; El Khatib, A.; Atiyeh, B.

    2010-01-01

    Burn wound cleansing is an integral step in every wound management protocol. Yet a lot of this practice is based on myth rather than real scientific basis. The literature is poor in scientific papers comparing the outcome of patients who underwent wound cleansing to those who did not. A survey form was designed by the Mediterranean Council for Burns and Fire Disasters - MBC and sent by e-mail to its members as well as members of the European Burn Association and other burn specialists, and 76...

  8. [Scoring system for early detection of critical illness can fail].

    Science.gov (United States)

    Kamstrup Christiansen, Lærke; Andreasen, Jo Bønding; Frederiksen, Christian Alcaraz; Juhl-Olsen, Peter; Sloth, Erik

    2013-02-18

    A 57-year old male underwent elective aortic valve replacement. The immediate post-operative course was uneventful and the patient was discharged with the lowest possible score on a newly implemented scale for early detection of critical illness. The following day he was readmitted with dyspnoea. The critical illness score was still low despite ultrasonic demonstration of a large pericardial effusion requiring drainage. We are concerned that the widely adopted critical illness scale is not sufficiently sensitive for cardiac surgery patients and advocate the use of point-of-care ultrasound.

  9. 76 FR 20366 - Changes to the Public Housing Assessment System (PHAS): Management Operations Scoring Notice

    Science.gov (United States)

    2011-04-12

    ... receivable. The interim Management Operations Scoring Notice was published on February 23, 2011 (76 FR 10050... URBAN DEVELOPMENT Changes to the Public Housing Assessment System (PHAS): Management Operations Scoring... request for public comments on the Management Operations interim scoring notice. The...

  10. Scoring system in cirrhotics due to viral hepatitis

    International Nuclear Information System (INIS)

    Objective: To determine the association of serum cholesterol levels with Child-Pugh class in patients with decompensated chronic liver disease due to viral hepatitis. Methodology: Consecutive patients attending outpatient department or admitted in medical unit III were eligible if they had a diagnosis of cirrhosis secondary to viral hepatitis. Patients were excluded if alcoholic, diabetic, hypertensive, or with non-alcoholic fatty liver disease, autoimmune, metabolic, cardiovascular, cerebrovascular or kidney diseases and recent use of lipid-regulating drugs. Serum lipid profile was determined after an overnight fast of 12 hours. On the basis of serum total cholesterol, patients were divided into four groups; Group I with serum total cholesterol = 100 mg/dl, Group II with level of 101-150 mg/dl, Group III with level of 151-200 mg/dl and Group IV with serum total cholesterol level of > 200 mg/dl. Hepatic dysfunction was categorized according to Child-Pugh scoring system. Chi-square and Spearman's correlation testing with p < 0.05 was accepted as significant. Results: One hundred and fourteen patients met the inclusion criteria with a mean age of 40.32 +- 13.59 years. Among these 32 were females (28.1%) while 82 were males (71.9%). According to Child-Pugh class; 34 patients (29.8%) presented with Child-Pugh class A, 34 (29.8%) in class B and 46 (40.4%) were in class C. Serum cholesterol (total) and triglycerides had significant association with Child-Pugh class (p = 0.0001 and p = 0.004 respectively) suggesting that as severity of liver dysfunction increases; serum cholesterol and triglycerides levels decrease. Results also revealed that males were significantly more hypocholesterolemic than females (p = 0.006). Conclusion: Hypocholesterolemia is a common finding in decompensated chronic liver disease and has got significant association with Child-Pugh class. It may increase the reliability of Child-Pugh classification in assessment of severity and prognosis in

  11. A Data Cleansing Method for Clustering Large-scale Transaction Databases

    CERN Document Server

    Loh, Woong-Kee; Kang, Jun-Gyu

    2010-01-01

    In this paper, we emphasize the need for data cleansing when clustering large-scale transaction databases and propose a new data cleansing method that improves clustering quality and performance. We evaluate our data cleansing method through a series of experiments. As a result, the clustering quality and performance were significantly improved by up to 165% and 330%, respectively.

  12. Clicker Score Trajectories and Concept Inventory Scores as Predictors for Early Warning Systems for Large STEM Classes

    Science.gov (United States)

    Lee, Un Jung; Sbeglia, Gena C.; Ha, Minsu; Finch, Stephen J.; Nehm, Ross H.

    2015-12-01

    Increasing the retention of STEM (science, technology, engineering, and mathematics) majors has recently emerged as a national priority in undergraduate education. Since poor performance in large introductory science and math courses is one significant factor in STEM dropout, early detection of struggling students is needed. Technology-supported "early warning systems" (EWSs) are being developed to meet these needs. Our study explores the utility of two commonly collected data sources—pre-course concept inventory scores and longitudinal clicker scores—for use in EWS, specifically, in determining the time points at which robust predictions of student success can first be established. The pre-course diagnostic assessments, administered to 287 students, included two concept inventories and one attitude assessment. Clicker question scores were also obtained for each of the 37 class sessions. Additionally, student characteristics (sex, ethnicity, and English facility) were gathered in a survey. Our analyses revealed that all variables were predictive of final grades. The correlation of the first 3 weeks of clicker scores with final grades was 0.53, suggesting that this set of variables could be used in an EWS starting at the third week. We also used group-based trajectory models to assess whether trajectory patterns were homogeneous in the class. The trajectory analysis identified three distinct clicker performance patterns that were also significant predictors of final grade. Trajectory analyses of clicker scores, student characteristics, and pre-course diagnostic assessment appear to be valuable data sources for EWS, although further studies in a diversity of instructional contexts are warranted.

  13. Systemic Inflammation Response Syndrome Score Predicts the Mortality in Multiple Trauma Patients

    OpenAIRE

    Baek, Jong Hyun; Kim, Myeong Su; Lee, Jung Cheul; Lee, Jang Hoon

    2014-01-01

    Background Numerous statistical models have been developed to accurately predict outcomes in multiple trauma patients. However, such trauma scoring systems reflect the patient’s physiological condition, which can only be determined to a limited extent, and are difficult to use when performing a rapid initial assessment. We studied the predictive ability of the systemic inflammatory response syndrome (SIRS) score compared to other scoring systems. Methods We retrospectively reviewed 229 patien...

  14. Is there a relationship between spinal instability in neoplastic disease and Tokuhashi scoring system?

    Science.gov (United States)

    de Oliveira, Matheus Fernandes; Rotta, Jose Marcus; Botelho, Ricardo Vieira

    2016-07-01

    Spinal instability neoplastic score (SINS) classification evaluates spinal stability by adding together six radiographic and clinical components. The objective of this study was to verify the association between SINS and Tokuhashi scoring system (TSS) score. Fifty-eight patients with vertebral metastases were admitted from 2010 to 2014 at Hospital do Servidor Público Estadual de São Paulo. They were evaluated according to their SINS and Tokuhashi SS score. Fourteen patients (24.13 %) scored from 0 to 6 points (stable spine), 37 (63.79 %) scored from 7 to 12 (potentially unstable), and 7 (12.06 %) scored from 13 to 18 (unstable). In stable spine patients according to SINS, the mean TSS score was 9.2. In potentially unstable spine patients, the mean TSS score was 8.24. In unstable spine patients, mean TSS score was 6.28. There was a statistically significant difference of the TSS score between stable and unstable patients. After evaluating TSS score in each patient, the worse the SINS, the worse was also the TSS score. PMID:26860530

  15. Further Validation of the Qualitative Scoring System for the Modified Bender-Gestalt Test.

    Science.gov (United States)

    Brannigan, Gary G.; And Others

    1995-01-01

    Compares the Qualitative Scoring System and the Developmental Scoring Systems, both Bender-Gestalt tests, in predicting achievement on the Metropolitan Achievement Test (MAT). In this study, first through fourth graders (n=409) from regular elementary schools were subjected to both tests; both systems correlated significantly with school…

  16. A new scoring system for predicting survival in patients with non-small cell lung cancer

    International Nuclear Information System (INIS)

    This analysis was performed to create a scoring system to estimate the survival of patients with non-small cell lung cancer (NSCLC). Data from 1274 NSCLC patients were analyzed to create and validate a scoring system. Univariate (UV) and multivariate (MV) Cox models were used to evaluate the prognostic importance of each baseline factor. Prognostic factors that were significant on both UV and MV analyses were used to develop the score. These included quality of life, age, performance status, primary tumor diameter, nodal status, distant metastases, and smoking cessation. The score for each factor was determined by dividing the 5-year survival rate (%) by 10 and summing these scores to form a total score. MV models and the score were validated using bootstrapping with 1000 iterations from the original samples. The score for each prognostic factor ranged from 1 to 7 points with higher scores reflective of better survival. Total scores (sum of the scores from each independent prognostic factor) of 32–37 correlated with a 5-year survival of 8.3% (95% CI = 0–17.1%), 38–43 correlated with a 5-year survival of 20% (95% CI = 13–27%), 44–47 correlated with a 5-year survival of 48.3% (95% CI = 41.5–55.2%), 48–49 correlated to a 5-year survival of 72.1% (95% CI = 65.6–78.6%), and 50–52 correlated to a 5-year survival of 84.7% (95% CI = 79.6–89.8%). The bootstrap method confirmed the reliability of the score. Prognostic factors significantly associated with survival on both UV and MV analyses were used to construct a valid scoring system that can be used to predict survival of NSCLC patients. Optimally, this score could be used when counseling patients, and designing future trials

  17. Application of a computed tomography based cystic fibrosis scoring system to chest tomosynthesis

    Science.gov (United States)

    Söderman, Christina; Johnsson, Åse; Vikgren, Jenny; Rystedt, Hans; Ivarsson, Jonas; Rossi Norrlund, Rauni; Nyberg Andersson, Lena; Bâth, Magnus

    2013-03-01

    In the monitoring of progression of lung disease in patients with cystic fibrosis (CF), recurrent computed tomography (CT) examinations are often used. The relatively new imaging technique chest tomosynthesis (CTS) may be an interesting alternative in the follow-up of these patients due to its visualization of the chest in slices at radiation doses and costs significantly lower than is the case with CT. A first step towards introducing CTS imaging in the diagnostics of CF patients is to establish a scoring system appropriate for evaluating the severity of CF pulmonary disease based on findings in CTS images. Previously, several such CF scoring systems based on CT imaging have been published. The purpose of the present study was to develop a CF scoring system for CTS, by starting from an existing scoring system dedicated for CT images and making modifications regarded necessary to make it appropriate for use with CTS images. In order to determine any necessary changes, three thoracic radiologists independently used a scoring system dedicated for CT on both CT and CTS images from CF patients. The results of the scoring were jointly evaluated by all the observers, which lead to suggestions for changes to the scoring system. Suggested modifications include excluding the scoring of air trapping and doing the scoring of the findings in quadrants of the image instead of in each lung lobe.

  18. Development of sonic technology for the daily cleansing of the skin.

    Science.gov (United States)

    Akridge, Robert E; Pilcher, Kenneth A

    2006-06-01

    Even though many skin cleansing products are commercially available, the cleansing of the skin is dependent upon the user's diligence, compliance, and technique, which often results in inconsistent cleansing. When the skin is inadequately or excessively cleansed, the skin becomes compromised, sometimes leading to acute or chronic conditions that may require medical attention. A sonic skincare brush was developed to enhance and provide consistent skin cleansing while preventing the skin from becoming compromised. Utilizing a technology previously used to cleanse the oral cavity, the sonic skincare brush is optimized to work with the skin's own elasticity providing rapid oscillatory flexing of the infundibular opening. By oscillating at sonic speed the net result is the inelastic comedones become loosened and detached from the infundibular wall and are then cleared from the acroinfundibulum. Although additional clinical research into the various applications of sonic skin care technology is needed, utilization of sonic technology is now available for effectively and consistently cleansing the skin. PMID:17173597

  19. Comparison of Two Scoring Systems for the Modified Version of the Bender-Gestalt Test.

    Science.gov (United States)

    Schachter, Steven; And Others

    1991-01-01

    Examined relative utility of two scoring systems for Modified Version of Bender-Gestalt Test in predicting performance on Developmental Test of Visual-Motor Integration. Findings from 53 kindergarten and 47 first grade students indicated that Qualitative Scoring System was significantly better predictor of visual-motor integration skills than…

  20. Comparison of the Koppitz and Watkins Scoring Systems for the Bender Gestalt Test.

    Science.gov (United States)

    Johnston, Cris W.; Lanak, Brenda

    1985-01-01

    The Bender Gestalt Test was administered to 25 children (7-10 years old) referred for neuropsychological assessment and scored using the Koppitz system and the Watkins system. Although the scores obtained using the two different sets of criteria were highly correlated, the Watkins rules produced generally better performance. (Author/CL)

  1. Developing a magnetic resonance imaging scoring system for peripheral psoriatic arthritis

    DEFF Research Database (Denmark)

    McQueen, Fiona; Lassere, Marissa; Bird, Paul;

    2007-01-01

    We describe the first steps in developing an OMERACT magnetic resonance imaging (MRI) scoring system for peripheral psoriatic arthritis (PsA). A preexisting MRI dataset (finger joints) from 10 patients with PsA was scored by 4 readers for bone erosion, bone edema, synovitis, tendinopathy, and ext......We describe the first steps in developing an OMERACT magnetic resonance imaging (MRI) scoring system for peripheral psoriatic arthritis (PsA). A preexisting MRI dataset (finger joints) from 10 patients with PsA was scored by 4 readers for bone erosion, bone edema, synovitis, tendinopathy...

  2. Validating a Prognostic Scoring System for Postmastectomy Locoregional Recurrence in Breast Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Skye Hung-Chun, E-mail: skye@kfsyscc.org [Department of Radiation Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan (China); Clinical Research Office, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan (China); Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Tsai, Stella Y. [Department of Radiation Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan (China); Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Yu, Ben-Long [Department of Surgery, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan (China); Horng, Cheng-Fang [Clinical Research Office, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan (China); Chen, Chii-Ming [Department of Surgery, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan (China); Jian, James J. [Department of Radiation Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan (China); Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Chu, Nan-Min [Department of Medical Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan (China); Tsou, Mei-Hua [Department of Pathology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan (China); Liu, Mei-Ching [Department of Medical Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan (China); Huang, Andrew T. [Department of Medical Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan (China); Department of Medicine, Duke University Medical Center, Durham, North Carolina (United States); Prosnitz, Leonard R. [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States)

    2013-03-15

    Purpose: This study is designed to validate a previously developed locoregional recurrence risk (LRR) scoring system and further define which groups of patients with breast cancer would benefit from postmastectomy radiation therapy (PMRT). Methods and Materials: An LRR risk scoring system was developed previously at our institution using breast cancer patients initially treated with modified radical mastectomy between 1990 and 2001. The LRR score comprised 4 factors: patient age, lymphovascular invasion, estrogen receptor negativity, and number of involved lymph nodes. We sought to validate the original study by examining a new dataset of 1545 patients treated between 2002 and 2007. Results: The 1545 patients were scored according to the previously developed criteria: 920 (59.6%) were low risk (score 0-1), 493 (31.9%) intermediate risk (score 2-3), and 132 (8.5%) were high risk (score ≥4). The 5-year locoregional control rates with and without PMRT in low-risk, intermediate-risk, and high-risk groups were 98% versus 97% (P=.41), 97% versus 91% (P=.0005), and 89% versus 50% (P=.0002) respectively. Conclusions: This analysis of an additional 1545 patients treated between 2002 and 2007 validates our previously reported LRR scoring system and suggests appropriate patients for whom PMRT will be beneficial. Independent validation of this scoring system by other institutions is recommended.

  3. [Effect of prosthesis cleansing agent on the prosthetic base fungi].

    Science.gov (United States)

    Temmer, K; Stipetić, D; Cekić-Arambasin, A; Kraljević, K

    1991-01-01

    Candida albicans and other fungi are frequently found in subjects wearing prostheses, especially in prostheses with poor hygiene, i.e. with accumulations of food, plaques and calculi. The aim of this study was to assess the efficacy of Corega extradent relative to fungi adhering to the prosthetic base. Results of the study showed the prosthesis hygiene to be substantially related to inflammation of palatal mucosa. The mean number of fungi per sq.cm of prosthetic base was 64 x 10(5). The number of fungi was redetermined after a two-day treatment with Corega extradent, with unchanged other habits of the prosthesis wearing and cleansing. The number of fungi decreased in all study subjects, the mean value of individual differences being 2238 times. In prostheses with a great number of fungi and extremely poor hygiene, the effect of Corega extradent was poorer, indicating the need of additional mechanical cleansing with a brush. PMID:1819938

  4. A rapid method for the presurgical cleansing of hands.

    Science.gov (United States)

    Decker, L A; Gross, A; Miller, F C; Read, J A; Cutright, D E; Devine, J

    1978-01-01

    A new rapid method of presurgical cleansing of the hands has been evaluated in a clinical setting. The effectiveness of a 90 second jet wash has been compared with a standard 10-minute presurgical scrub. Bacteriologic cultures were obtained from the fingertips of interns, residents, and staff of the Department of Obstetrics and Gynecology of the Walter Reed Army Medical Center before and after 90-second jet washings and 10-minute conventional scrubs. The results showed that the 90-second jet wash was more effective in degerming the hands than the 10-minute standard brush scrub. Other advantages of the new method, such as the amount of time saved, the standardization of cleansing, and reduced skin irritation are discussed. PMID:619330

  5. The safety of osmotically acting cathartics in colonic cleansing

    DEFF Research Database (Denmark)

    Nyberg, Caroline; Hendel, J.; Nielsen, O.H.

    2010-01-01

    Efficient cleansing of the colon before a colonoscopy or a radiological examination is essential. The osmotically acting cathartics (those given the Anatomical Therapeutic Chemical code A06AD) currently used for this purpose comprise products based on three main substances: sodium phosphate......, combinations of polyethylene glycol and electrolyte lavage solutions (PEG-ELS), and magnesium citrate. All these preparations give adequate cleansing results and have similar profiles in terms of the frequency and type of mild to moderate adverse effects. However, serious adverse events, such as severe...... hyperphosphatemia and irreversible kidney damage owing to acute phosphate nephropathy, have been reported after use of sodium-phosphate-based products. The aim of this Review is to provide an update on the potential safety issues related to the use of osmotically acting cathartics, especially disturbances of renal...

  6. An Iranian scoring system for diagnosing Buerger's disease.

    Directory of Open Access Journals (Sweden)

    Mohammad Ramin

    2014-01-01

    Full Text Available Buerger's disease or thromboangiitis obliterans (TAO seems to be common in IR Iran, The present study aimed to evaluate an Iranian population with Buerger's disease in order to suggest a diagnostic criterion for Buerger's disease based on the most frequent findings and to compare it with Papa diagnostic criteria. In a cross-sectional study, all patients with resting limb pain, limb ischemic ulcers, intermittent claudication and limb ischemia who referred to the Vascular Clinic of Sina Hospital during 2009-2011 were evaluated. The patients were allocated to Buerger's and non-Buerger's groups; Evaluating 122 patients (61 in each group, according to the model each clinical manifestations and risk factors in the patients with Buerger's disease obtained a score. Absent pulsation, abnormal distal Doppler sonography and ischemic ulcer were respectively present in 58 (95.1%, 58 (95.1% and 49 (80.3% individuals with Buerger's disease. Multivariate linear regression analysis and multivariate logistic regression analysis were used for modeling. Considering the model finding findings, diagnostic criteria including age, sex, smoking, Raynaud's phenomenon, abnormal proximal Doppler, diabetes mellitus and hyperlipidemia were suggested (R2=0.582; the sensitivity and specificity of the criteria was respectively 95.1% and 78.7%. Compared with Papa criteria, Kappa coefficient was measured at 0.66 with a P-value<0.001. It seems that the recommended criteria have an acceptable accuracy in diagnosing Buerger's disease, especially in the Iranian population; however, it is necessary to conduct more studies with larger sample sizes to evaluate the criteria, especially in other populations.

  7. The OMERACT psoriatic arthritis magnetic resonance imaging scoring system (PsAMRIS): definitions of key pathologies, suggested MRI sequences, and preliminary scoring system for PsA Hands

    DEFF Research Database (Denmark)

    Østergaard, Mikkel; McQueen, Fiona; Wiell, Charlotte;

    2009-01-01

    This article describes a preliminary OMERACT psoriatic arthritis magnetic resonance image scoring system (PsAMRIS) for evaluation of inflammatory and destructive changes in PsA hands, which was developed by the international OMERACT MRI in inflammatory arthritis group. MRI definitions of importan...... pathologies in peripheral PsA and suggestions concerning appropriate MRI sequences for use in PsA hands are also provided.......This article describes a preliminary OMERACT psoriatic arthritis magnetic resonance image scoring system (PsAMRIS) for evaluation of inflammatory and destructive changes in PsA hands, which was developed by the international OMERACT MRI in inflammatory arthritis group. MRI definitions of important...

  8. Bank Customer Credit Scoring by Using Fuzzy Expert System

    Directory of Open Access Journals (Sweden)

    Ali Bazmara

    2014-10-01

    Full Text Available Granting banking facility is one of the most important parts of the financial supplies for each bank. So this activity becomes more valuable economically and always has a degree of risk. These days several various developed Artificial Intelligent systems like Neural Network, Decision Tree, Logistic Regression Analysis, Linear Discriminant Analysis and etc, are used in the field of granting facilities that each of this system owns its advantages and disadvantages. But still studying and working are needed to improve the accuracy and performance of them. In this article among other AI methods, fuzzy expert system is selected. This system is based on data and also extracts rules by using data. Therefore the dependency to experts is omitted and interpretability of rules is obtained. Validity of these rules could be confirmed or rejected by banking affair experts. For investigating the performance of proposed system, this system and some other methods were performed on various datasets. Results show that the proposed algorithm obtained better performance among the others.

  9. Scoring System Approach for Assessment of Critical Illness using Mobile Phones

    Directory of Open Access Journals (Sweden)

    Karupothula Madhavi Latha

    2012-02-01

    Full Text Available This paper demonstrates the use of mobile phones in assessing the illness of patients by developing a Scoring Systemwhere medical practitioners (often nurses collect various physiological signals like ECG, EEG, SpO2, temperature, continuous blood pressure and subjective parameters like level of pain, level of alertness, awareness, behavioral responses etc. After taking the data, a scoring system is utilized for early detection of critical illnesses. The mechanism of scoring is performed either manually, where the medical practitioner ticks on to a scoring board or is automated by relocating the information from scoring board to a PC, where the software performs the scoring calculation. In the proposed system, the medical practitioner inputs the parameters directly on to their mobile phone by collecting the parameters fromthe patient. The score is automatically calculated by miniature java based software running inside themobile phone. Based on the score, level of urgency is determined by the intelligent program. At the end, specialists are contacted automatically by messaging services. Moreover, the results of the scoring are transmitted to the hospital server. Therefore, assistance from civilians with mobile phone based medical intelligence can save precious life.

  10. The Koppitz Developmental Scoring System for the Bender-Gestalt: Is It Developmental?

    Science.gov (United States)

    Taylor, Ronald L.; And Others

    1984-01-01

    Investigated the developmental aspects of the Koppitz scoring system with 652 children who took the Bender Motor Gestalt Test. Scores were fitted to various developmental curves by computer. Results indicated only 35 percent of the Bender test performance variance was accounted for by age. (JAC)

  11. Developing a magnetic resonance imaging scoring system for peripheral psoriatic arthritis

    DEFF Research Database (Denmark)

    McQueen, Fiona; Lassere, Marissa; Bird, Paul;

    2007-01-01

    We describe the first steps in developing an OMERACT magnetic resonance imaging (MRI) scoring system for peripheral psoriatic arthritis (PsA). A preexisting MRI dataset (finger joints) from 10 patients with PsA was scored by 4 readers for bone erosion, bone edema, synovitis, tendinopathy, and...

  12. Simplified Therapeutic Intervention Scoring System : The TISS-28 items - Results from a multicenter study

    NARCIS (Netherlands)

    Miranda, DR; deRijk, A; Schaufeli, W

    1996-01-01

    Objectives: To validate a simplified version of the Therapeutic Intervention Scoring System, the TISS-28, and to determine the association of TISS-28 with the time spent on scored and nonscored nursing activities. Design: Prospective, multicenter study. Setting: Twenty-two adult medical, surgical, a

  13. 76 FR 10050 - Changes to the Public Housing Assessment System (PHAS): Management Operations Scoring Notice

    Science.gov (United States)

    2011-02-23

    ... URBAN DEVELOPMENT Changes to the Public Housing Assessment System (PHAS): Management Operations Scoring... of the public about HUD's process for issuing scores under the management operations indicator of the... process for the PHAS management operations indicator. The purpose of the management operations...

  14. The Validity of Preservice Teacher Use of Kohlberg's Issue Stage Scoring System

    Science.gov (United States)

    Napier, John D.

    1978-01-01

    Social studies preservice teachers received background information on Kohlberg's theory of moral development and were trained to use one of the rater guides in his new "issue stage scoring system." They were directed to score sample moral thought statements, some on an intuitive basis and some with the rater guides. No overall differences between…

  15. External validation of a clinical scoring system for the risk of gestational diabetes mellitus

    NARCIS (Netherlands)

    van Leeuwen, M.; Opmeer, B. C.; Zweers, E. J. K.; van Ballegooie, E.; ter Brugge, H. G.; de Valk, H. W.; Visser, G. H. A.; Mol, B. W. J.

    2009-01-01

    Aim: A prediction rule for gestational diabetes mellitus (GDM) could be helpful in early detection and increased efficiency of screening. A prediction rule by means of a clinical scoring system is available, but has never been validated externally. The aim of this study was to validate the scoring s

  16. Small diameter gravity sewers: self-cleansing conditions and aspects of wastewater quality.

    Science.gov (United States)

    Dias, S P; Matos, J S

    2001-01-01

    The construction of conventional sewerage systems in small communities, with pipes laid on a uniform slope and manholes regularly spaced, is sometimes not economically feasible, because of the high costs of sewer installation. Under those circumstances, the small diameter gravity sewers (SDGS) have often proven to be substantially less costly than conventional sewers. Typically, in SDGS systems the wastewater from one or more households is discharged into an interceptor tank (or a single compartment septic tank). The settled effluent is discharged afterwards into small diameter sewers operating under gravity. In this paper, special emphasis is given to the analysis of self-cleansing conditions and to the analysis of risks of sulphide generation and occurrence of septic conditions in SDGS systems. For the evaluation of the self-cleansing conditions, the critical velocity and the critical shear stress were computed according to the Shields equation. The forecasting of dissolved oxygen concentrations and sulphide build-up along the lines, for different flow conditions, was done running an established wastewater quality model. PMID:11379122

  17. Progress Scored in Management Information System at CAS

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ CAS initiative to upgrade its management information system (MIS) is making significant progress. Recently, 116 CAS subordinates have completed their online trial operation of a MIS project at the Academy, called Academia Resource Planning (ARP), marking an important phased achievement of the initiative.

  18. Building an Image-Based System to automatically Score psoriasis

    DEFF Research Database (Denmark)

    G{'o}mez, D. Delgado; Carstensen, Jens Michael; Ersbøll, Bjarne Kjær

    2003-01-01

    images. The system is tested on patients with the dermatological disease psoriasis. Temporal series of images are taken for each patient and the lesions are automatically extracted. Results indicate that to the images obtained are a good source for obtaining derived variables to track the lesion....

  19. A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer

    OpenAIRE

    David G. Watt; Roxburgh, Campbell S.; Mark White; Juen Zhik Chan; Horgan, Paul G; McMillan, Donald C

    2015-01-01

    Introduction. The systemic inflammatory response (SIR) plays a key role in determining nutritional status and survival of patients with cancer. A number of objective scoring systems have been shown to have prognostic value; however, their application in routine clinical practice is not clear. The aim of the present survey was to examine the range of opinions internationally on the routine use of these scoring systems. Methods. An online survey was distributed to a target group consisting of i...

  20. The timing of bowel preparation before colonoscopy determines the quality of cleansing, and is a significant factor contributing to the detection of flat lesions: A randomized study

    Institute of Scientific and Technical Information of China (English)

    Adolfo Parra-Blanco; David Nicolás-Pérez; Antonio Gimeno-García; Bego(n)a Grosso; Alejandro Jiménez; Juan Ortega; Enrique Quintero

    2006-01-01

    AIM: To compare the cleansing quality of polyethylene glycol electrolyte solution and sodium phosphate with different schedules of administration, and to evaluate whether the timing of the administration of bowel preparation affects the detection of polyps.METHODS: One hundred and seventy-seven consecutive outpatients scheduled for colonoscopy were randomized in one of four groups to receive polyethylene glycol electrolyte solution or oral sodium phosphate with two different timing schedules. Quality of cleansing, polyp detection, and tolerance were evaluated.RESULTS: Patients receiving polyethylene glycol or sodium phosphate on the same day as the colonoscopy,obtained good to excellent global cleansing scores more frequently than patients who received polyethylene glycol or sodium phosphate on the day prior to the procedure (P< 0.001). Flat lesions, but not flat adenomas, were more frequent in patients prepared on the same day (P = 0.02).CONCLUSION: The quality of colonic cleansing and the detection of flat lesions are significantly improved when the preparation is taken on the day of the colonoscopy.

  1. Beyond the SYNTAX score--advantages and limitations of other risk assessment systems in left main percutaneous coronary intervention.

    Science.gov (United States)

    Capodanno, Davide

    2013-01-01

    Risk stratification is an emerging topic in the modern management of patients with left main disease referred for percutaneous coronary intervention (PCI). Recent years have witnessed an explosive multiplication of risk models for prognostic stratification in complex PCI. Many of this models deal with modification of the angiographic SYNTAX score, or seek to overcome its known pitfalls and limitations, including lack of clinical and functional information, inter- and intra-observer variabilities, and poor calibration. Risk scoring systems beyond the SYNTAX score may be classified into angiographic (residual SYNTAX score, coronary artery bypass grafting SYNTAX score), clinical (EuroSCORE I and II, ACEF score and modified ACEF scores), combined clinical and angiographic (Global Risk Classification, Clinical SYNTAX score, logistic Clinical SYNTAX score, SYNTAX score II) and functional (Functional SYNTAX score). This article reviews current concepts in risk modeling and explores the advantages and limitations of the alternatives to the SYNTAX score in patients undergoing left main PCI. 

  2. Risk scoring systems for adults admitted to the emergency department: a systematic review

    DEFF Research Database (Denmark)

    Brabrand, Mikkel; Folkestad, Lars; Clausen, Nicola G;

    2010-01-01

    . Even though most scoring systems are not meant to be used on an individual level, they can support the more inexperienced doctors and nurses in assessing the risk of deterioration of their patients. We therefore performed a systematic review on the level of evidence of literature on scoring systems...... developed or validated in the MAU. We hypothesized that existing scoring systems would have a low level of evidence and only few systems would have been externally validated. METHODS: We conducted a systematic search using Medline, EMBASE and the Cochrane Library, according to the PRISMA guidelines......, on scoring systems developed to assess medical patients at admission. The primary endpoints were in-hospital mortality or transfer to the intensive care unit. Studies derived for only a single or few diagnoses were excluded. The ability to identify patients at risk (discriminatory power) and agreement...

  3. Commercial Building Energy Asset Score System: Program Overview and Technical Protocol (Version 1.0)

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Na; Gorrissen, Willy J.

    2013-01-11

    The U.S. Department of Energy (DOE) is developing a national voluntary energy asset score system that includes an energy asset score tool to help building owners evaluate their buildings with respect to the score system. The goal of the energy asset score system is to facilitate cost-effective investment in energy efficiency improvements of commercial buildings. The system will allow building owners and managers to compare their building infrastructure against peers and track building upgrade progress over time. The system can also help other building stakeholders (e.g., building operators, tenants, financiers, and appraisers) understand the relative efficiency of different buildings in a way that is independent from their operations and occupancy. This report outlines the technical protocol used to generate the energy asset score, explains the scoring methodology, and provides additional details regarding the energy asset score tool. This report also describes alternative methods that were considered prior to developing the current approach. Finally, this report describes a few features of the program where alternative approaches are still under evaluation.

  4. Diffuse Fatty Infiltration of the Liver: US Scoring System Correlated with CT and LFT

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jin Seong [Seoul district Armed Forces General Hospital, Seoul (Korea, Republic of)

    1994-12-15

    The present study was performed to estimate the accuracy of US examination in predicting the hepatic function in patients with diffuse fatty infiltration of the Liver. We compared the findings at US with the findings at CT and biochemical hepatic function test. US was performed by using 3.5MHz sector prove. We evaluated the US findings in terms or the degree of acoustic attenuation from the liver, the parenchymal echogenicity, the distinction of the portal vein wall, and the distinction of the diaphragm. Each parameter was graded into the numeric scores ranging from 0 to 2. The total US score was calculated from the scores of the four parameters. The total US score was compared with the difference in Hounsfield Units between the liver and spleen on nonenhanced CT images. The total US score was also compared with the aspartate(AST) and alanine transaminase(ALT) levels in peripheral blood. There was statistically significant correlation between the total US score and the difference in Hounsfield Unit between the liver and spleen on CT (r=0.7074, p<0.0001). When the total US score above 4 was considered as acriteria, the AST or ALT level were abnormal within the sensitivity of 90% and specificity of 60%. When the total US score above 5 was considered as a criteria, the sensitivity and specificity were 78% and 79%, respectively. In conclusion, US scoring system is useful in predicting the abnormal hepatic function in patients with diffuse fatty infiltration of the liver

  5. Ultrafast CT scoring system for assessing bronchopulmonary dysplasia. Reproducibility and clinical correlation

    International Nuclear Information System (INIS)

    To evaluate the reproducibility of the Ultrafast CT (UFCT) scoring system and assess its usefulness in monitoring clinical severity in infants with bronchopulmonary dysplasia (BPD). UFCT scoring was done in 22 infants (15 boys and 7 girls aged 1 to 37 months) with BPD. A total of 258 lung fields were evaluated for the presence of hyperaeration, linear opacities, triangular subpleural opacities, and bronchovascular bundle distortion or thickening, and UFCT scores were given. Intraobserver and interobserver agreement and reproducibility of UFCT scores were statistically analyzed. In 12 patients, UFCT scores were linearly correlated with clinical severity scores based on respiratory dysfunction and complexity of care. 'Hyperaeration,' which was the most frequent (18 of 22, 81.8%) finding, showed high concordance (κ=0.73, p<0.001, κ=0.59, p<0.001), and its UFCT scores significantly correlated with intraobserver and interobserver analyses (r=0.94, p<0.001, r=0.82, p<0.001, respectively). UFCT scores for hyperaeration significantly correlated with clinical scores (r=0.75, p<0.01), whereas those for the others did not. UFCT is useful for assessing BPD. Hyperaeration was the most common and reproducible finding, and its extent significantly correlated with clinical severity. (author)

  6. Assessment of the EuroSCORE risk scoring system for patients undergoing coronary artery bypass graft surgery in a group of Iranian patients

    Directory of Open Access Journals (Sweden)

    Hamidreza Jamaati

    2015-01-01

    Full Text Available Background and Aims: Previous studies around the world indicated validity and accuracy of European System for Cardiac Operative Risk Evaluation (EuroSCORE risk scoring system we evaluated the EuroSCORE risk scoring system for patients undergoing coronary artery bypass graft (CABG surgery in a group of Iranian patients. Materials and Methods: In this cohort 2220 patients more than 18 years, who were performed CABG surgery in Massih Daneshvari Hospital, from January 2004 to March 2010 were recruited. Predicted mortality risk scores were calculated using logistic EuroSCORE and Acute Physiology and Chronic Health Evaluation II (APACHE II and compared with observed mortality. Calibration was measured by the Hosmer-Lemeshow (HL test and discrimination by using the receiver operating characteristic (ROC curve area. Results: Of the 2220 patients, in hospital deaths occurred in 270 patients (mortality rate of 12.2%. The accuracy of mortality prediction in the logistic EuroSCORE and APACHE II model was 89.1%; in the local EuroSCORE (logistic was 91.89%; and in the local EuroSCORE support vector machines (SVM was 98.6%. The area under curve for ROC curve, was 0.724 (95% confidence interval [CI]: 0.57-0.88 for logistic EuroSCORE; 0.836 (95% CI: 0.731-0.942 for local EuroSCORE (logistic; 0.978 (95% CI: 0.937-1 for Local EuroSCORE (SVM; and 0.832 (95% CI: 0.723-0.941 for APACHE II model. The HL test showed good calibration for the local EuroSCORE (SVM, APACHE II model and local EuroSCORE (logistic (P = 0.823, P = 0.748 and P = 0.06 respectively; but there was a significant difference between expected and observed mortality according to EuroSCORE model (P = 0.033. Conclusion: We detected logistic EuroSCORE risk model is not applicable on Iranian patients undergoing CABG surgery.

  7. Assessment of an implant-skin interface scoring system for external skeletal fixation of dogs.

    Science.gov (United States)

    McDonald-Lynch, Mischa B; Marcellin-Little, Denis J; Roe, Simon C; Lascelles, B Duncan X; Trumpatori, Brian J; Griffith, Emily H

    2015-11-01

    OBJECTIVE To assess intraobserver repeatability and interobserver and in vivo versus photographic agreement of a scoring system for the implant-skin interface (ISI) of external skeletal fixation (ESF). SAMPLE 42 photographs of ISIs from 18 dogs for interobserver agreement and intraobserver repeatability and 27 photographs of ISIs from 6 dogs for in vivo versus photograph agreement. PROCEDURES An ISI inflammation scoring system was developed. It included scales for 6 metrics (erythema, drainage amount, drainage type, swelling, hair loss or lack of hair regrowth, and granulation tissue). Photographs of the ISI of ESF were obtained by use of a standard protocol and evaluated to determine intraobserver repeatability and interobserver agreement (Cronbach α; 4 raters) of the ISI score. Agreement between in vivo and photographic ISI scores (2 raters) and correlation between median scores across metrics were evaluated. RESULTS 42 photographs met the inclusion criteria. Overall intraclass correlation coefficients ranged from 0.922 to 0.975. Interobserver overall Cronbach α ranged from 0.835 to 0.943. For in vivo versus photographic assessment, 27 ISIs in 6 dogs and their photographs were evaluated. The Cronbach α for both raters ranged from 0.614 to 0.938. Overall, the Cronbach α ranged from 0.725 to 0.932. Mean photographic scores were greater than mean in vivo scores for each metric. Pearson correlation coefficients ranged from 0.221 to 0.923. Erythema, swelling, and granulation were correlated with all other metrics. CONCLUSIONS AND CLINICAL RELEVANCE In this study, an ISI scoring system used in this study had high repeatability and agreement and may therefore be considered for use in clinical situations. Photographic scores were not equivalent to in vivo scores and should not be used interchangeably.

  8. Prediction of 18-month survival in patients with primary myelodysplastic syndrome. A regression model and scoring system based on the combination of chromosome findings and the Bournemouth score.

    Science.gov (United States)

    Parlier, V; van Melle, G; Beris, P; Schmidt, P M; Tobler, A; Haller, E; Bellomo, M J

    1995-06-01

    The predictive potential of six selected factors was assessed in 72 patients with primary myelodysplastic syndrome using univariate and multivariate logistic regression analysis of survival at 18 months. Factors were age (above median of 69 years), dysplastic features in the three myeloid bone marrow cell lineages, presence of chromosome defects, all metaphases abnormal, double or complex chromosome defects (C23), and a Bournemouth score of 2, 3, or 4 (B234). In the multivariate approach, B234 and C23 proved to be significantly associated with a reduction in the survival probability. The similarity of the regression coefficients associated with these two factors means that they have about the same weight. Consequently, the model was simplified by counting the number of factors (0, 1, or 2) present in each patient, thus generating a scoring system called the Lausanne-Bournemouth score (LB score). The LB score combines the well-recognized and easy-to-use Bournemouth score (B score) with the chromosome defect complexity, C23 constituting an additional indicator of patient outcome. The predicted risk of death within 18 months calculated from the model is as follows: 7.1% (confidence interval: 1.7-24.8) for patients with an LB score of 0, 60.1% (44.7-73.8) for an LB score of 1, and 96.8% (84.5-99.4) for an LB score of 2. The scoring system presented here has several interesting features. The LB score may improve the predictive value of the B score, as it is able to recognize two prognostic groups in the intermediate risk category of patients with B scores of 2 or 3. It has also the ability to identify two distinct prognostic subclasses among RAEB and possibly CMML patients. In addition to its above-described usefulness in the prognostic evaluation, the LB score may bring new insights into the understanding of evolution patterns in MDS. We used the combination of the B score and chromosome complexity to define four classes which may be considered four possible states of

  9. The development of a preliminary ultrasonographic scoring system for features of hand osteoarthritis.

    LENUS (Irish Health Repository)

    Keen, H I

    2008-05-01

    Painful osteoarthritis (OA) of the hand is common and a validated ultrasound (US) scoring system would be valuable for epidemiological and therapeutic outcome studies. US is increasingly used to assess peripheral joints, though most of the US focus in rheumatic diseases has been on rheumatoid arthritis. We aimed to develop a preliminary US hand OA scoring system, initially focusing on relevant pathological features with potentially high reliability.

  10. Lameness scoring system for dairy cows using force plates and artificial intelligence.

    Science.gov (United States)

    Ghotoorlar, S Mokaram; Ghamsari, S Mehdi; Nowrouzian, I; Ghotoorlar, S Mokaram; Ghidary, S Shiry

    2012-02-01

    Lameness scoring is a routine procedure in dairy industry to screen the herds for new cases of lameness. Subjective lameness scoring, which is the most popular lameness detection and screening method in dairy herds, has several limitations. They include low intra-observer and inter-observer agreement and the discrete nature of the scores which limits its usage in monitoring the lameness. The aim of this study is to develop an automated lameness scoring system comparable with conventional subjective lameness scoring by means of artificial neural networks. The system is composed of four balanced force plates installed in a hoof-trimming box. A group of 105 dairy cows was used for the study. Twenty-three features extracted from ground reaction force (GRF) data were used in a computer training process which was performed on 60 per cent of the data. The remaining 40 per cent of the data were used to test the trained system. Repeatability of the lameness scoring system was determined by GRF samples from 25 cows, captured at two different times from the same animals. The mean sd was 0.31 and the mean coefficient of variation was 14.55 per cent, which represents a high repeatability in comparison with subjective vision-based scoring methods. Although the highest sensitivity and specificity values were seen in locomotion score groups 1 and 4, the automatic lameness system was both sensitive and specific in all groups. The sensitivity and specificity were higher than 72 per cent in locomotion score groups 1 to 4, and it was 100 per cent specific and 50 per cent sensitive for group 5. PMID:22141114

  11. A sonographic scoring system to assess the risk of thyroid malignancy.

    Science.gov (United States)

    Pathirana, A A; Bandara, K G M W; Faleel, M A; Kuruppumullage, S D; Solangarachchi, N; Rupasinghe, R D; Karunaratne, N P N; Ranasinghe, D D; Epa, W A; Thusyanthan, V

    2016-03-01

    Prediction of thyroid malignancy with fine needle aspiration cytology or individual ultrasound characteristics has several limitations. This study evaluates the usefulness of a combination of ultrasound characteristics in predicting malignancy in patients with thyroid nodules. We assessed 189 thyroid nodules using ultrasonography and histology. Each nodule was assigned a score based on ultrasonographic characteristics. This score was compared with histology to identify ability to predict malignancy. There were 28 malignant nodules. The scoring system was appropriate for clinical use, obtaining an area under ROC curve of 0.822 [p< 0.0001] 95% confidence. FNAC of nodules with a score of more than 4 can be recommended (100% sensitivity). Nodules with a score less than 8 can be offered total thyroidectomy when FNAC is inconclusive (97.5% sensitivity). A combination of ultrasonographic criteria increase the accuracy of predicting malignancy in thyroid nodules. PMID:27031977

  12. A Review of Current Issues Underlying Colon Cleansing before Colonoscopy

    Directory of Open Access Journals (Sweden)

    Lawrence C Hookey

    2007-01-01

    Full Text Available The present review examines four current issues related to the efficacy, patient tolerance and safety of the following bowel cleansing agents: oral sodium phosphate (NaP, polyethylene glycol (PEG and magnesium citrate (Pico-Salax, Ferring Pharmaceuticals Inc, Canada, an agent recently made available in Canada. MedLine and PubMed databases were systematically searched to identify studies related to the efficacy of altered PEG solutions combined with adjunct treatments; the efficacy, tolerability and safety of Pico-Salax; the association between nephrocalcinosis, and chronic renal failure and oral NaP use; and the role of diet. Although lower volume PEG solutions combined with adjuvant agents were generally associated with better patient tolerance, their efficacy was varied and interpretation of this end point is complicated by study design issues. There are very few reported studies of Pico-Salax, and as a result, there are insufficient data to draw conclusions about the efficacy of this agent. The available data suggest that Pico-Salax may be better tolerated by patients, than oral NaP and PEG solutions. There is a paucity of hemodynamic monitoring data pre- and postadministration, but the available data suggests that this small-volume osmotic agent could cause subclinical contraction of the intravascular space. Recent case reports suggest an association between nephrocalcinosis and oral NaP ingestion, but to date, these reports have been confined to a single centre. Preliminary studies suggest that this is not a widespread problem, but more studies are needed. There are only a few studies examining diet and patient tolerability, but they do suggest that diet may be liberalized with some cleansing regimens to enhance tolerability without decreasing efficacy. The present review highlights current controversies and advances in colon cleansing before colonoscopy, and also identifies areas for further study.

  13. [Interproximal tooth cleansing of abutment teeth and pontic design].

    Science.gov (United States)

    Kocher, T; Plagmann, H C; Engelsmann, U; Schlüter, R

    1990-03-01

    This clinical study was an attempt to find out if a patient's home care plaque control at his or her abutment tooth is more effectively enhanced by a modified ridge lap or a hygienic pontic design. Oral hygiene was performed either with a tooth brush alone or in combination with an interdental brush. We found that the effectivity of interproximal toothcleaning was not influenced by the pontic design and that only interdental brushes permit a good plaque control at the proximal area of the abutment tooth. This implies that "self cleansing" is non-existent in these tooth areas. PMID:2257819

  14. Information System Of Student Score SMA Negeri 1 Tegal Based On Short Message Service (SMS Gateway

    Directory of Open Access Journals (Sweden)

    Zaenul Arif

    2016-06-01

    Full Text Available Student Score at the agency school is one measure of the success of students in learning the material presented. In the old system the parents have not been getting the value directly from the school except at the end of each semester, making them difficult to know the value of their children's development during school. To provide score transparency to students and parents needed an information system score subjects in an easy and fast data access. By identifying the problem is analyzing the old system to identify the weaknesses of the system. Thus the new system will increase. Analysis of the weakness of the old system using PIECES categories (Performance, Information, Economy, Control, Eficiency, and Service. In fulfilling these conditions, build up lesson student score information system of Short Message Service (SMS Gateway Based. The system is built using Gammu software and using the programming language PHP. By using SMS to obtain the score of the data is expected to provide convenience for parents to monitor learning outcomes of their children’s in school.

  15. Analysis of WHO-Based Prognostic Scoring System (WPSS) of Myelodysplastic Syndrome and Its Comparison with International Prognostic Scoring System (IPSS) in 100 Chinese Patients

    Institute of Scientific and Technical Information of China (English)

    Jia Wei; Xiao-fen Zhou; Jian-feng Zhou; Yan Chen

    2009-01-01

    Objective: The aims of this study were to assess the prognostic significance of WHO-based Prognostic Scoring System (WPSS) in myelodysplastic syndrome (MDS) from a single center institute and to compare WPSS with the international prognostic scoring system (IPSS).Methods: A total of 100 cases with de novo MDS were reviewed and their karyotypes were detected. All of them were followed up and classified according to IPSS and WPSS risk groups. SPSS 13.0 software was applied to deal with all the data. The statistical methods included Kaplan - Meier, Log-rank test and cox regression.Results: Multivariate cox regression analysis indicated that WHO Classification (P=0.0190), karyotype abnormalities categorized according to IPSS (P=0.0159) and red blood cell (RBC) transfusion (P=0.0009) were the three most important independent factors for predicting overall survival (OS) of MDS. WPSS and IPSS both had great capacity in predicting the OS of MDS at the time of diagnosis (P<0.0001). In time-dependent analysis, WPSS can predict the OS accurately in the following three years after diagnosis (P<0.0001), while IPSS failed to predict the OS 24 months after diagnosis (P=0.1094).Conclusion: Our single center results proved that WPSS is a dynamic prognostic system which can predict the OS of MDS patients at any time during the course of their disease. This time-dependent prognostic scoring system may replace the IPSS in the near future.

  16. An audit of the current U.S. Department of Agriculture frame size scoring system.

    Science.gov (United States)

    Reinhardt, C D; Busby, W D

    2014-06-01

    Feedlot and carcass data from steers (n = 16,700) and heifers (n = 6,357) originating from 16 different states and fed in 17 feedlots located in southwest Iowa were used to evaluate the accuracy of the USDA frame score for predicting final BW of fed cattle. Frame score was recorded by USDA or state personnel for cattle either before leaving the state of origin or on arrival at the terminal feedlot. Mixed model procedures were used to investigate relationships between USDA frame score and measures of live performance and carcass traits. Other fixed effects included in the model included USDA muscle score, sex, age classification on feedlot entry (calf: ≤270 d of age, yearling: 271-365 d of age, and long yearling: >365 d of age), BCS on feedlot arrival, number of treatments for respiratory disease, hide color, and site of frame or muscle scoring; the interactions of sex × frame score and hide color × frame score were also included; fat thickness was included as a fixed effect (covariate) in the analysis of ADG, final BW, days on feed, LM area, marbling score, and quality grade. Random effects included in the model were year of feedlot arrival and feedlot in which cattle were fed. The system accurately projects the minimum target final BW for large frame steers and heifers; however, the final BW of the smallest medium frame steers and heifers exceeds the target minimum final BW by 35 and 40 kg, respectively. When frame score was assigned post facto based on actual final BW (adjusted to 1.27 cm fat thickness), it was determined that large frame was over-assigned by graders (62 vs. 35% for steers and 54 vs. 32% for heifers, actual score vs. postharvest score, respectively), medium frame was underassigned (37 vs. 51% and 46 vs. 58% for steers and heifers), and small frame was underassigned (0.7 vs. 15% and 0.6 vs. 10% for steers and heifers; K = 0.01, P cattle assigned to small, medium, or large frame score, 40, 59, and 43% actually had final BW (adjusted to 1.27 cm

  17. Evaluation of rheumatoid arthritis using a scoring system devised from magnetic resonance imaging of rheumatoid knees

    International Nuclear Information System (INIS)

    We studied the magnetic resonance imaging (MRI) of 120 knees in 86 rheumatoid arthritis (RA) patients and of 14 unaffected knees in 12 control cases. We also developed a scoring system as a quantitative analysis method. We divided the MRI into 10 items, and classified the severity of the symptoms into 4 grades (score 0 to 3). The average total score increased according to the radiographic grade. Soft tissue lesions were clearly detected, even in the early stages of RA. Items such as synovial proliferation showed a high score even in the early stages, suggesting that it was the initial symptom of RA. The score also showed a correlation with the inflammatory signs. These results suggest that this scoring system is very sensitive and yields a good reflection of RA activity. We demonstrated that this system is simple and convenient for routine diagnostic use. We further demonstrated that it is useful for following the advancement of RA and for evaluating the response to treatment. (author)

  18. The PERS(2) ON score for systemic assessment of symptomatology in palliative care: a pilot study.

    Science.gov (United States)

    Masel, E K; Berghoff, A S; Schur, S; Maehr, B; Schrank, B; Simanek, R; Preusser, M; Marosi, C; Watzke, H H

    2016-07-01

    The comprehensive assessment of symptoms is the basis for effective, individualised palliative treatment. Established scoring systems provide in-depth information but are often lengthy and hence unsuitable. We introduce the PERS(2) ON score as a short and practically feasible score to evaluate symptom burden. Fifty patients admitted to a Palliative Care Unit rated seven items, i.e. pain, eating (loss of appetite/weight loss), rehabilitation (physical impairment), social situation (possibility for home care), suffering (anxiety/burden of disease/depression), O2 (dyspnoea) and nausea/emesis, on a scale ranging from 0 (absence) to 10 (worst imaginable), resulting in a score ranging from 0 to 70. Assessments were performed at admission, 7 days after admission and at the day of discharge. Symptom intensity scores were calculated, and change over time was evaluated. A significant improvement was observed from the PERS²ON score between admission and 7 days (P evaluation to evaluation on the day of discharge was observed (P = 0.001; paired t-test). This study provides initial evidence that the PERS²ON score is both feasible and sensitive to changes of the most prominent symptoms in palliative care. It may be useful in clinical practice to direct palliative treatment strategies and provide targeted symptom management. PMID:26564404

  19. New Eye Cleansing Product Improves Makeup-Related Ocular Problems.

    Science.gov (United States)

    Okura, Masako; Kawashima, Motoko; Katagiri, Mikiyuki; Shirasawa, Takuji; Tsubota, Kazuo

    2015-01-01

    Purpose. This study evaluated the effects of using a newly developed eye cleansing formulation (Eye Shampoo) to cleanse the eyelids for 4 weeks in a parallel-group comparative study in women with chronic eye discomfort caused by heavy use of eye makeup and poor eye hygiene habits. Methods. Twenty women participants who met the inclusion criteria were randomly allocated to 2 groups comprising 10 participants each. The participants were asked to use either artificial tears alone or artificial tears in conjunction with Eye Shampoo for 4 weeks. The participants answered the questionnaire again and were reexamined, and changes in symptoms within each group and variations of symptoms between the two groups were statistically analyzed. Results. In the group using only artificial tears, improvements in subjective symptoms but not in ophthalmologic examination results were found. In the group using Eye Shampoo together with artificial tears, significant improvements were observed in the subjective symptoms, meibomian orifice obstruction, meibum secretion, tear breakup time, and superficial punctate keratopathy. Conclusion. In patients with chronic eye discomfort thought to be caused by heavy eye makeup, maintaining eyelid hygiene using Eye Shampoo caused a marked improvement in meibomian gland blockage and dry eye symptoms.

  20. New Eye Cleansing Product Improves Makeup-Related Ocular Problems

    Directory of Open Access Journals (Sweden)

    Masako Okura

    2015-01-01

    Full Text Available Purpose. This study evaluated the effects of using a newly developed eye cleansing formulation (Eye Shampoo to cleanse the eyelids for 4 weeks in a parallel-group comparative study in women with chronic eye discomfort caused by heavy use of eye makeup and poor eye hygiene habits. Methods. Twenty women participants who met the inclusion criteria were randomly allocated to 2 groups comprising 10 participants each. The participants were asked to use either artificial tears alone or artificial tears in conjunction with Eye Shampoo for 4 weeks. The participants answered the questionnaire again and were reexamined, and changes in symptoms within each group and variations of symptoms between the two groups were statistically analyzed. Results. In the group using only artificial tears, improvements in subjective symptoms but not in ophthalmologic examination results were found. In the group using Eye Shampoo together with artificial tears, significant improvements were observed in the subjective symptoms, meibomian orifice obstruction, meibum secretion, tear breakup time, and superficial punctate keratopathy. Conclusion. In patients with chronic eye discomfort thought to be caused by heavy eye makeup, maintaining eyelid hygiene using Eye Shampoo caused a marked improvement in meibomian gland blockage and dry eye symptoms.

  1. Development of a simple reliable radiographic scoring system to aid the diagnosis of pulmonary tuberculosis.

    Directory of Open Access Journals (Sweden)

    Lancelot M Pinto

    Full Text Available RATIONALE: Chest radiography is sometimes the only method available for investigating patients with possible pulmonary tuberculosis (PTB with negative sputum smears. However, interpretation of chest radiographs in this context lacks specificity for PTB, is subjective and is neither standardized nor reproducible. Efforts to improve the interpretation of chest radiography are warranted. OBJECTIVES: To develop a scoring system to aid the diagnosis of PTB, using features recorded with the Chest Radiograph Reading and Recording System (CRRS. METHODS: Chest radiographs of outpatients with possible PTB, recruited over 3 years at clinics in South Africa were read by two independent readers using the CRRS method. Multivariate analysis was used to identify features significantly associated with culture-positive PTB. These were weighted and used to generate a score. RESULTS: 473 patients were included in the analysis. Large upper lobe opacities, cavities, unilateral pleural effusion and adenopathy were significantly associated with PTB, had high inter-reader reliability, and received 2, 2, 1 and 2 points, respectively in the final score. Using a cut-off of 2, scores below this threshold had a high negative predictive value (91.5%, 95%CI 87.1,94.7, but low positive predictive value (49.4%, 95%CI 42.9,55.9. Among the 382 TB suspects with negative sputum smears, 229 patients had scores <2; the score correctly ruled out active PTB in 214 of these patients (NPV 93.4%; 95%CI 89.4,96.3. The score had a suboptimal negative predictive value in HIV-infected patients (NPV 86.4, 95% CI 75,94. CONCLUSIONS: The proposed scoring system is simple, and reliably ruled out active PTB in smear-negative HIV-uninfected patients, thus potentially reducing the need for further tests in high burden settings. Validation studies are now required.

  2. A computed tomography scoring system to assess pulmonary disease among premature infants

    Energy Technology Data Exchange (ETDEWEB)

    Boechat, Marcia Cristina Bastos; Mello, Rosane Reis de; Silva, Katia Silveira da; Daltro, Pedro; Marchiori, Edson; Ramos, Eloane Guimaraes; Dutra, Maria Virginia Peixoto, E-mail: marciabboechat@gmail.co [Instituto Fernandes Figueira (IFF/FIOCRUZ), Rio de Janeiro, RJ (Brazil)

    2010-07-01

    Context and objective: high-resolution computed tomography (HRCT) is considered to be the best method for detailed pulmonary evaluation. The aim here was to describe a scoring system based on abnormalities identified on HRCT among premature infants, and measure the predictive validity of the score in relation to respiratory morbidity during the first year of life. Design and setting: prospective cohort study in Instituto Fernandes Figueira, Fundacao Oswaldo Cruz. Methods: scoring system based on HRCT abnormalities among premature newborns. The affected lung area was quantified according to the number of compromised lobes, in addition to bilateral pulmonary involvement. Two radiologists applied the score to 86 HRCT scans. Intraobserver and interobserver agreement were analyzed. The score properties were calculated in relation to predictions of respiratory morbidity during the first year of life. Results: most of the patients (85%) presented abnormalities on HRCT, and among these, 56.2% presented respiratory morbidity during the first year of life. Scores ranged from zero to 12. There was good agreement between observers (intraclass correlation coefficient, ICC = 0.86, confidence interval, CI: 0.64-0.83). The predictive scores were as follows: positive predictive value 81.8%, negative predictive value 56.3%, sensitivity 39.1%, and specificity 90.0%. Conclusion: the scoring system is reproducible, easy to apply and allows HRCT comparisons among premature infants, by identifying patients with greater likelihood of respiratory morbidity during the first year of life. Its use will enable HRCT comparisons among premature infants with different risk factors for respiratory morbidity. (author)

  3. A computed tomography scoring system to assess pulmonary disease among premature infants

    International Nuclear Information System (INIS)

    Context and objective: high-resolution computed tomography (HRCT) is considered to be the best method for detailed pulmonary evaluation. The aim here was to describe a scoring system based on abnormalities identified on HRCT among premature infants, and measure the predictive validity of the score in relation to respiratory morbidity during the first year of life. Design and setting: prospective cohort study in Instituto Fernandes Figueira, Fundacao Oswaldo Cruz. Methods: scoring system based on HRCT abnormalities among premature newborns. The affected lung area was quantified according to the number of compromised lobes, in addition to bilateral pulmonary involvement. Two radiologists applied the score to 86 HRCT scans. Intraobserver and interobserver agreement were analyzed. The score properties were calculated in relation to predictions of respiratory morbidity during the first year of life. Results: most of the patients (85%) presented abnormalities on HRCT, and among these, 56.2% presented respiratory morbidity during the first year of life. Scores ranged from zero to 12. There was good agreement between observers (intraclass correlation coefficient, ICC = 0.86, confidence interval, CI: 0.64-0.83). The predictive scores were as follows: positive predictive value 81.8%, negative predictive value 56.3%, sensitivity 39.1%, and specificity 90.0%. Conclusion: the scoring system is reproducible, easy to apply and allows HRCT comparisons among premature infants, by identifying patients with greater likelihood of respiratory morbidity during the first year of life. Its use will enable HRCT comparisons among premature infants with different risk factors for respiratory morbidity. (author)

  4. Developing points-based risk-scoring systems in the presence of competing risks.

    Science.gov (United States)

    Austin, Peter C; Lee, Douglas S; D'Agostino, Ralph B; Fine, Jason P

    2016-09-30

    Predicting the occurrence of an adverse event over time is an important issue in clinical medicine. Clinical prediction models and associated points-based risk-scoring systems are popular statistical methods for summarizing the relationship between a multivariable set of patient risk factors and the risk of the occurrence of an adverse event. Points-based risk-scoring systems are popular amongst physicians as they permit a rapid assessment of patient risk without the use of computers or other electronic devices. The use of such points-based risk-scoring systems facilitates evidence-based clinical decision making. There is a growing interest in cause-specific mortality and in non-fatal outcomes. However, when considering these types of outcomes, one must account for competing risks whose occurrence precludes the occurrence of the event of interest. We describe how points-based risk-scoring systems can be developed in the presence of competing events. We illustrate the application of these methods by developing risk-scoring systems for predicting cardiovascular mortality in patients hospitalized with acute myocardial infarction. Code in the R statistical programming language is provided for the implementation of the described methods. © 2016 The Authors. Statistics in Medicine published by John Wiley & Sons Ltd. PMID:27197622

  5. The MELD scoring system for predicting prognosis in patients with severe hepatitis after plasma exchange treatment

    Institute of Scientific and Technical Information of China (English)

    Jian-Wu Yu; Gui-Qiang Wang; Yong-Hua Zhao; Li-Jie Sun; Shu-Qin Wang; Shu-Chen Li

    2007-01-01

    BACKGROUND:Hepatic failure caused by severe hepatitis is a clinical syndrome where the major liver functions, particularly detoxiifcation, synthetic functions, and metabolic regulation are impaired to different degrees, and may result in major life-threatening complications such as hepatic encephalopathy, ascites, jaundice, cholestasis, bleeding and hepatorenal syndrome. Plasma exchange (PE) has been found useful in treating patients with fulminant hepatic failure by removing hepatic toxins and replacement of clotting factors, so PE treatment has temporary supportive effects on liver failure caused by severe viral hepatitis. In this study, our aim was to predict the prognosis of patients with severe hepatitis after PE treatment using the end-stage liver disease (MELD) scoring system. METHODS:Two hundred and twenty patients were randomly divided into PE and control groups, and the MELD score was calculated for each patient according to the original formula. The efifcacy of PE was assessed by mortality or improvement in biochemical parameters and MELD score. RESULTS: The levels of total bilirubin and international normalised ratio (INR) in patients whose MELD scores were between 30 and 39 were lower than those before PE treatment, as those in patients whose MELD scores were 40 or higher. The mortality of patients in the PE group with MELD scores from 30 to 39 was 50.0%, while it was 83.3%in the control group (P0.05). CONCLUSIONS:PE treatment can decrease the serum total bilirubin level and INR and MELD score of patients with severe hepatitis and improve liver function. Compared with the control group, PE can signiifcantly decrease the mortality of patients with MELD scores from 30 to 39, but has no effect in patients with MELD scores of 40 or higher.

  6. Determining utility values in patients with anterior cruciate ligament tears using clinical scoring systems

    Directory of Open Access Journals (Sweden)

    Szucs Thomas

    2011-08-01

    Full Text Available Abstract Background Several instruments and clinical scoring systems have been established to evaluate patients with ligamentous knee injuries. A comparison of individual articles in the literature is challenging, not only because of heterogeneity in methodology, but also due to the variety of the scoring systems used to document clinical outcomes. There is limited information about the correlation between used scores and quality of life with no information being available on the impact of each score on the utility values. The aim of this study was to compare the most commonly used scores for evaluating patients with anterior cruciate ligament (ACL injuries, and to establish corresponding utility values. These values will be used for the interpretation and comparison of outcome results in the currently available literature for different treatment options. Methods Four hypothetical vignettes were defined, based on different levels of activities after rupture of the ACL to simulate typical situations seen in daily practice. A questionnaire, including the Health Utility Index (HUI for utility values, the IKDC subjective score, the Lysholm and the Tegner score, was created and 25 orthopedic surgeons were asked to fill the questionnaire for each hypothetical patient as proxies for all patients they had treated and who would fit in that hypothetical vignette. Results The utility value as an indicator for quality of life increased with the level of activity. Having discomforts already during normal activities of daily living was rated with a mean utility value of 0.37 ± 0.19, half of that of a situation where mild sport activity was possible without discomfort (0.78 ± 0.11. All investigated scores were able to distinguish clearly (p Conclusions Here we report the correlation between the most commonly used scores for the assessment of patients with a ruptured ACL and utility values as an indicator of quality of life. Assumptions were based on expert

  7. Prognostic nomogram integrated systemic inflammation score for patients with esophageal squamouscell carcinoma undergoing radical esophagectomy

    OpenAIRE

    Yingjie Shao; Zhonghua Ning; Jun Chen; Yiting Geng; Wendong Gu; Jin Huang; Honglei Pei; Yueping Shen; Jingting Jiang

    2015-01-01

    Growing evidence indicates that nomogram combined with the biomarkers of systemic inflammation response could provide more accurate prediction than conventional staging systems in tumors. This study aimed to establish an effective prognostic nomogram for resectable thoracic esophageal squamouscell carcinoma (ESCC) based on the clinicopathological parameters and inflammation-based prognostic scores. We retrospectively investigated 916 ESCC patients who underwent radical esophagectomy. The pred...

  8. High Reliability of a Scoring System for Implant Position in Undisplaced Femoral Neck Fractures

    DEFF Research Database (Denmark)

    Viberg, Bjarke; Bartholin, Marie-Louise L; Weber, Kolja;

    2016-01-01

    OBJECTIVES: The aim of this study was to evaluate the intra-rater and inter-rater reliability of a scoring system for internal fixation (SIFA) in undisplaced femoral neck fractures (FNF). DESIGN: A reproducibility study with a historical consecutive cohort. SETTING: The patients were all treated...... of the screw position in femoral head had the largest difference of acceptable positioning, when comparing visual assessment with the measured. CONCLUSIONS: The SIFA scoring system demonstrates substantial intra-rater and inter-rater reliability (kappa (0.51-0.78), when raters make measurements of radiographs......, but lower reliability (kappa 0.13-0.78) when raters visually assess the radiographs without measuring. The SIFA scoring system should be assessed on a large cohort for correlation with clinical evaluation....

  9. The scoring system for patients with severe sepsis after orthotopic liver transplantation

    Institute of Scientific and Technical Information of China (English)

    Shun-Wei Huang; Xiang-Dong Guan; Xiao-Shun He; Juan Chen; Bin Ouyang

    2006-01-01

    BACKGROUND:Because of the complicated pathological features after liver transplantation, severe sepsis is dififcult to treat and often leads to death. This study was undertaken to analyze the role of orthotopic liver transplantation (OLT) in patients with severe sepsis and to evaluate the effect of the scoring system. METHODS:Fifty-six patients conformed to the inclusion criteria. They were divided into two groups: non-OLT group (group A) and OLT group (group B). Besides the general data of the patients, the surveillance of blood lactate, the number of failed organs, acute physiology and chronic health evaluationⅡ(APACHEⅡ) and mutiple organ dysfunction score (MODS) were evaluated at the 1st, 3rd and 7th day after OLT. RESULTS:The mortality during hospitalization was 30%in the non-OLT group and 57.6%in the other group. The level of blood lactate at the 1st day of OLT increased more signiifcantly in the OLT group than in the non-OLT group (P CONCLUSIONS: The persistently higher level of blood lactate during 7 days may be a dependent risk factor. Immunosuppression may be another risk factor for OLT patients. The mortality of OLT in patients with severe sepsis in 28 days is almost double that in non-OLT patients. The MODS score is better than the APACHEⅡscore in the assessment of organ failure in OLT patients with severe sepsis. The standard scoring system could be improved or a new scoring system that includes the blood lactate score should be established for liver transplantation.

  10. A Comparison of Systemic Inflammation-Based Prognostic Scores in Patients on Regular Hemodialysis

    Directory of Open Access Journals (Sweden)

    Akihiko Kato

    2013-10-01

    Full Text Available Background/Aims: Systemic inflammation-based prognostic scores have prognostic power in patients with cancer, independently of tumor stage and site. Although inflammatory status is associated with mortality in hemodialysis (HD patients, it remains to be determined as to whether these composite scores are useful in predicting clinical outcomes. Methods: We calculated the 6 prognostic scores [Glasgow prognostic score (GPS, modified GPS (mGPS, neutrophil-lymphocyte ratio (NLR, platelet lymphocyte ratio (PLR, prognostic index (PI and prognostic nutritional index (PNI], which have been established as a useful scoring system in cancer patients. We enrolled 339 patients on regular HD (age: 64 ± 13 years; time on HD: 129 ± 114 months; males/females = 253/85 and followed them for 42 months. The area under the receiver-operating characteristics curve was used to determine which scoring system was more predictive of mortality. Results: Elevated GPS, mGPS, NLR, PLR, PI and PNI were all associated with total mortality, independent of covariates. If GPS was raised, mGPS, NLR, PLR and PI were also predictive of all-cause mortality and/or hospitalization. GPS and PNI were associated with poor nutritional status. Using overall mortality as an endpoint, the area under the curve (AUC was significant for a GPS of 0.701 (95% CI: 0.637-0.765; p Conclusion: GPS, based on serum albumin and highly sensitive C-reactive protein, has the most prognostic power for mortality prediction among the prognostic scores in HD patients. However, as the determination of serum albumin reflects mortality similarly to GPS, other composite combinations are needed to provide additional clinical utility beyond that of albumin alone in HD patients.

  11. PyParse: a semiautomated system for scoring spoken recall data.

    Science.gov (United States)

    Solway, Alec; Geller, Aaron S; Sederberg, Per B; Kahana, Michael J

    2010-02-01

    Studies of human memory often generate data on the sequence and timing of recalled items, but scoring such data using conventional methods is difficult or impossible. We describe a Python-based semiautomated system that greatly simplifies this task. This software, called PyParse, can easily be used in conjunction with many common experiment authoring systems. Scored data is output in a simple ASCII format and can be accessed with the programming language of choice, allowing for the identification of features such as correct responses, prior-list intrusions, extra-list intrusions, and repetitions.

  12. Primary graft dysfunction; possible evaluation by high resolution computed tomography, and suggestions for a scoring system

    DEFF Research Database (Denmark)

    Belmaati, Esther; Jensen, Claus; Kofoed, Klaus F;

    2009-01-01

    , and reproducibility of these systems were discussed. Lastly, the future perspectives for 64-multi-slice computed tomography (MSCT) in relation to PGD were discussed. Few studies on scoring systems of lung tissue by HRCT in ARDS patients and idiopathic pulmonary fibrosis (IPF) patients were found. Most studies were...... performed on patients with cystic fibrosis (CF). Sensitivity of HRCT for the detection of parenchymal changes is superior to other imaging methods. High levels of reproducibility are achievable amongst observers who score HRCT lung images. Development of standardized criteria that specify the inclusion...

  13. Evaluation of a novel feather scoring system for monitoring feather damaging behaviour in parrots.

    Science.gov (United States)

    van Zeeland, Yvonne R A; Bergers, Madeleine J; van der Valk, Lisette; Schoemaker, Nico J; Lumeij, Johannes T

    2013-05-01

    Feather damaging behaviour is common in captive psittacine birds and there is a need for reliable methods to evaluate the efficacy of therapeutic and preventive interventions. This study compared the inter- and intra-observer reliabilities of a novel feather scoring system with an existing system to assess the plumage of grey parrots (Psittacus erithacus). Regions of the body were photographed separately at 1 week intervals and shown at random to 35 examiners (avian veterinarians and veterinary students), who used the two scoring systems to assess plumage. Since the quality of the photographs was insufficient to allow accurate assessment of the individual flight and tail feathers, the novel scoring system was only evaluated for its reliability regarding covert and down feathers. Inter- and intra-observer reliabilities were determined using the intra-class correlation coefficient. Bland-Altman analysis was performed to determine absolute reliabilities for both systems. Correlation coefficients were 0.90 and 0.95 for intra-observer reliability and 0.83 and 0.89 for inter-observer reliability for the existing and novel feather scoring systems, respectively. When using the novel system, a change in plumage condition of ≥10% was needed to ensure that the change reflected a real difference in 95% of cases, while a change of ≥15% was needed for the existing system. Since it may take from 4 weeks (covert or down feathers) to over 1 year (flight or tail feathers) for feathers to regrow, sufficient time should be allowed to elapse between two scoring sessions to reliably evaluate the efficacy of preventive or therapeutic interventions for feather damaging behaviour.

  14. Prediction of Carotid Artery Stenosis in Candidates of Coronary Artery Bypasses Surgery by A Scoring System.

    Directory of Open Access Journals (Sweden)

    Sh. Shirani

    2007-05-01

    Full Text Available Background and Objective: Up to 9% of coronary ar-tery bypass grafting (CABG patients suffer from stroke after the surgery. Although post CABG stroke has multiple etiologies, stenosis of cervical carotid arteries is an important factor. Many studies have evaluated carotid artery stenosis in CABG. Carotid stenosis and its related factors and a new scoring sys-tem for selection of CABG patients for Doppler study are introduced. Materials and methods: 1721 consecutive cases of non-urgent CABG were evaluated for presence of significant carotid stenosis (> 50% stenosis. The asso-ciation of age, sex, hypertension, smoking, diabetes, dislipidemia and left main coronary stenosis with ca-rotid stenosis was evaluated. For introducing a scor-ing method, absence of each related factor was scored by 1 and its presence by 2. The score range for each patient was from 5 (none of related factors up to 10 (all of related factors. Results: 7% of patients suffered from significant stenosis. Female gender, age more than 55 years old, hypertension, diabetes, and stenosis of left main coronary artery were the related risk factors in uni-variate analysis. A step type analysis revealed patients with score 5 have 98.3% negative predictive value (NPV for significant stenosis with 96.2% sensitivity and 13.9% specificity. Patients with score 10 have 93.9% NPV for significant stenosis with 99.9% speci-ficity. Conclusion: This scoring system may help for better selection of patients for Doppler study before CABG.

  15. Liver stiffness measurement-based scoring system for significant inflammation related to chronic hepatitis B.

    Directory of Open Access Journals (Sweden)

    Mei-Zhu Hong

    Full Text Available Liver biopsy is indispensable because liver stiffness measurement alone cannot provide information on intrahepatic inflammation. However, the presence of fibrosis highly correlates with inflammation. We constructed a noninvasive model to determine significant inflammation in chronic hepatitis B patients by using liver stiffness measurement and serum markers.The training set included chronic hepatitis B patients (n = 327, and the validation set included 106 patients; liver biopsies were performed, liver histology was scored, and serum markers were investigated. All patients underwent liver stiffness measurement.An inflammation activity scoring system for significant inflammation was constructed. In the training set, the area under the curve, sensitivity, and specificity of the fibrosis-based activity score were 0.964, 91.9%, and 90.8% in the HBeAg(+ patients and 0.978, 85.0%, and 94.0% in the HBeAg(- patients, respectively. In the validation set, the area under the curve, sensitivity, and specificity of the fibrosis-based activity score were 0.971, 90.5%, and 92.5% in the HBeAg(+ patients and 0.977, 95.2%, and 95.8% in the HBeAg(- patients. The liver stiffness measurement-based activity score was comparable to that of the fibrosis-based activity score in both HBeAg(+ and HBeAg(- patients for recognizing significant inflammation (G ≥3.Significant inflammation can be accurately predicted by this novel method. The liver stiffness measurement-based scoring system can be used without the aid of computers and provides a noninvasive alternative for the prediction of chronic hepatitis B-related significant inflammation.

  16. Liver Stiffness Measurement-Based Scoring System for Significant Inflammation Related to Chronic Hepatitis B

    Science.gov (United States)

    Hong, Mei-Zhu; Zhang, Ru-Mian; Chen, Guo-Liang; Huang, Wen-Qi; Min, Feng; Chen, Tian; Xu, Jin-Chao; Pan, Jin-Shui

    2014-01-01

    Objectives Liver biopsy is indispensable because liver stiffness measurement alone cannot provide information on intrahepatic inflammation. However, the presence of fibrosis highly correlates with inflammation. We constructed a noninvasive model to determine significant inflammation in chronic hepatitis B patients by using liver stiffness measurement and serum markers. Methods The training set included chronic hepatitis B patients (n = 327), and the validation set included 106 patients; liver biopsies were performed, liver histology was scored, and serum markers were investigated. All patients underwent liver stiffness measurement. Results An inflammation activity scoring system for significant inflammation was constructed. In the training set, the area under the curve, sensitivity, and specificity of the fibrosis-based activity score were 0.964, 91.9%, and 90.8% in the HBeAg(+) patients and 0.978, 85.0%, and 94.0% in the HBeAg(−) patients, respectively. In the validation set, the area under the curve, sensitivity, and specificity of the fibrosis-based activity score were 0.971, 90.5%, and 92.5% in the HBeAg(+) patients and 0.977, 95.2%, and 95.8% in the HBeAg(−) patients. The liver stiffness measurement-based activity score was comparable to that of the fibrosis-based activity score in both HBeAg(+) and HBeAg(−) patients for recognizing significant inflammation (G ≥3). Conclusions Significant inflammation can be accurately predicted by this novel method. The liver stiffness measurement-based scoring system can be used without the aid of computers and provides a noninvasive alternative for the prediction of chronic hepatitis B-related significant inflammation. PMID:25360742

  17. A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer

    Directory of Open Access Journals (Sweden)

    David G. Watt

    2015-01-01

    Full Text Available Introduction. The systemic inflammatory response (SIR plays a key role in determining nutritional status and survival of patients with cancer. A number of objective scoring systems have been shown to have prognostic value; however, their application in routine clinical practice is not clear. The aim of the present survey was to examine the range of opinions internationally on the routine use of these scoring systems. Methods. An online survey was distributed to a target group consisting of individuals worldwide who have reported an interest in systemic inflammation in patients with cancer. Results. Of those invited by the survey (n=238, 65% routinely measured the SIR, mainly for research and prognostication purposes and clinically for allocation of adjuvant therapy or palliative chemotherapy. 40% reported that they currently used the Glasgow Prognostic Score/modified Glasgow Prognostic Score (GPS/mGPS and 81% reported that a measure of systemic inflammation should be incorporated into clinical guidelines, such as the definition of cachexia. Conclusions. The majority of respondents routinely measured the SIR in patients with cancer, mainly using the GPS/mGPS for research and prognostication purposes. The majority reported that a measure of the SIR should be adopted into clinical guidelines.

  18. A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer

    Science.gov (United States)

    Watt, David G.; Roxburgh, Campbell S.; White, Mark; Chan, Juen Zhik; Horgan, Paul G.; McMillan, Donald C.

    2015-01-01

    Introduction. The systemic inflammatory response (SIR) plays a key role in determining nutritional status and survival of patients with cancer. A number of objective scoring systems have been shown to have prognostic value; however, their application in routine clinical practice is not clear. The aim of the present survey was to examine the range of opinions internationally on the routine use of these scoring systems. Methods. An online survey was distributed to a target group consisting of individuals worldwide who have reported an interest in systemic inflammation in patients with cancer. Results. Of those invited by the survey (n = 238), 65% routinely measured the SIR, mainly for research and prognostication purposes and clinically for allocation of adjuvant therapy or palliative chemotherapy. 40% reported that they currently used the Glasgow Prognostic Score/modified Glasgow Prognostic Score (GPS/mGPS) and 81% reported that a measure of systemic inflammation should be incorporated into clinical guidelines, such as the definition of cachexia. Conclusions. The majority of respondents routinely measured the SIR in patients with cancer, mainly using the GPS/mGPS for research and prognostication purposes. The majority reported that a measure of the SIR should be adopted into clinical guidelines. PMID:26504363

  19. The safety of osmotically acting cathartics in colonic cleansing

    DEFF Research Database (Denmark)

    Nyberg, Caroline; Hendel, J.; Nielsen, O.H.

    2010-01-01

    hyperphosphatemia and irreversible kidney damage owing to acute phosphate nephropathy, have been reported after use of sodium-phosphate-based products. The aim of this Review is to provide an update on the potential safety issues related to the use of osmotically acting cathartics, especially disturbances of renal......Efficient cleansing of the colon before a colonoscopy or a radiological examination is essential. The osmotically acting cathartics (those given the Anatomical Therapeutic Chemical code A06AD) currently used for this purpose comprise products based on three main substances: sodium phosphate...... function and water and electrolyte balance. The available evidence indicates that PEG-ELS-based products are the safest option. Magnesium-citrate-based, hypertonic products should be administered with caution to elderly individuals and patients who are prone to develop disturbances in water and electrolyte...

  20. Proposal of a CT scoring system of the paranasal sinuses in diagnosing cystic fibrosis

    International Nuclear Information System (INIS)

    The purpose of this study was to develop a paranasal sinus CT scoring system that could be used as a diagnostic tool to discriminate cystic fibrosis (CF) patients from control patients examined for sinonasal disease. The model should include as few and easily applicable criteria as possible, supported by statistical analyses and clinical judgement. We used data from 116 CF and 136 control patients. The CF patients were grouped according to the number of confirmed CF mutations: genetically verified (CF-2), or based on sweat testing and clinical findings alone (CF-1, CF-0). Nine paranasal sinus CT criteria, including development, pneumatisation variants and inflammatory patterns, were evaluated. The final model included three criteria: (a) frontal and (b) sphenoid sinus development, and (c) absence of three pneumatisation variants. This model discriminated CF-2 from controls with overlap of summed scores in only 8 of 206 patients. When this model was applied in the CF-1 and CF-0 groups, two populations seemed to exist. A larger group with summed scores overlapping that of the CF-2 group and a smaller group with summed scores overlapping that of the control group. We conclude that this CT scoring system may support, as well as exclude, a CF diagnosis in cases of diagnostic uncertainty. (orig.)

  1. Modified PADSS (Post Anaesthetic Discharge Scoring System) for monitoring outpatients discharge.

    Science.gov (United States)

    Palumbo, Piergaspare; Tellan, Guglielmo; Perotti, Bruno; Pacilè, Maria Antonietta; Vietri, Francesco; Illuminati, Giulio

    2013-01-01

    The decision to discharge a patient undergoing day surgery is a major step in the hospitalization pathway, because it must be achieved without compromising the quality of care, thus ensuring the same assistance and wellbeing as for a long-term stay. Therefore, the use of an objective assessment for the management of a fair and safe discharge is essential. The authors propose the Post Anaesthetic Discharge Scoring System (PADSS), which considers six criteria: vital signs, ambulation, nausea/vomiting, pain, bleeding and voiding. Each criterion is given a score ranging from 0 to 2. Only patients who achieve a score of 9 or more are considered ready for discharge. Furthermore, PADSS has been modified to ensure a higher level of safety, thus the "vital signs" criteria must never score lower than 2, and none of the other five criteria must ever be equal to 0, even if the total score reaches 9. The effectiveness of PADSS was analyzed on 2432 patients, by recording the incidence of postoperative complications and the readmission to hospital. So far PADDS has proved to be an efficient system that guarantees safe discharge. PMID:23165318

  2. Ultrasonography-guided percutaneous radiofrequency ablation of hepatocellular carcinomas: A feasibility scoring system for planning sonography

    Energy Technology Data Exchange (ETDEWEB)

    Rhim, Hyunchul, E-mail: rhimhc@skku.ed [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Choi, Dongil; Kim, Young-sun; Lim, Hyo K. [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Choe, Bong-Keun [Department of Preventive Medicine, Kyung Hee University School of Medicine, Seoul (Korea, Republic of)

    2010-08-15

    Purpose: This study was designed to evaluate whether a feasibility scoring system for planning sonography is a reliable predictor of a safe and complete ablation in ultrasonography (US)-guided percutaneous radiofrequency ablation (RFA) of hepatocellular carcinomas (HCCs). Materials and methods: We retrospectively evaluated the therapeutic outcomes of 108 consecutive patients (M:F, 78:30; mean age, 57.4 years) with a single nodular HCC (mean diameter, 2.0 cm) treated by percutaneous RFA. All patients were assessed for the feasibility of performing an RFA at planning sonography prior to the ablation. The feasibility scoring system consisted of five categories: the safe electrode path (P); the vital organs adjacent to the RFA zone (O); tumor size (S); tumor conspicuity (C); and the heat-sink effect (H). Each category was divided into a four-point scale [1-4]. If a score of 4 in any category was determined, the patient was not considered to be a suitable candidate for percutaneous RFA. We assessed if the score of each category, safety score (P + O), and curability score (S + C + H) correlated with a safe and complete ablation using the chi-squared test and likelihood ratio test for trend. Results: The technical success rate was 100% (108/108) based on CT images obtained immediately after ablation. There was no 30-day mortality after RFA. There were major complications (one case of severe vasovagal reflex, one case of hemoperitoneum and one case of a pseudoaneurysm) in three (2.7%) patients, and minor complications (one case of a biloma, one case of subsegmental infarction and one case of abscess) in three (2.7%) patients. Post-ablation syndrome as a side effect was noted in 38 (35.1%) of 108 patients. The primary technique effectiveness rate at 1 month was 95.1% (105/108). Local tumor progression was noted in eight (7.6%) of 105 patients during the follow-up period (range, 3.0-11.5 months; median, 5.8 months; mean, 5.7 months). There was no significant single category

  3. 76 FR 10053 - Changes to the Public Housing Assessment System (PHAS): Capital Fund Scoring Notice

    Science.gov (United States)

    2011-02-23

    ..., Office of Public and Indian Housing, Real Estate Assessment Center (REAC), 550 12th Street, SW., Suite... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT Changes to the Public Housing Assessment System (PHAS): Capital Fund Scoring...

  4. Reliability of the Advanced Psychodiagnostic Interpretation (API) Scoring System for the Bender Gestalt.

    Science.gov (United States)

    Aucone, Ernest J.; Raphael, Alan J.; Golden, Charles J.; Espe-Pfeifer, Patricia; Seldon, Jen; Pospisil, Tanya; Dornheim, Liane; Proctor-Weber, Zoe; Calabria, Michael

    1999-01-01

    Assessed the interrater reliability of the revised Advanced Psychodiagnostic Interpretation (API) (A. Raphael and C. Golden, 1998) scoring system for the Bender Gestalt Test (L. Bender, 1938). Agreement across nine raters exceeded 90% for each of three clinical protocols, and kappa statistics indicated good interrater reliability. (SLD)

  5. 76 FR 16350 - Medical Devices; Ovarian Adnexal Mass Assessment Score Test System; Labeling; Black Box Restrictions

    Science.gov (United States)

    2011-03-23

    ... addition of this black box warning to product labeling, advertising, and marketing materials, the Agency... Assessment Score Test System; Labeling; Black Box Restrictions AGENCY: Food and Drug Administration, HHS... be in a black box and must appear in all labeling, advertising, and promotional material. The...

  6. Usefulness of staging systems and prognostic scores for hepatocellular carcinoma treatments.

    Science.gov (United States)

    Adhoute, Xavier; Penaranda, Guillaume; Raoul, Jean Luc; Le Treut, Patrice; Bollon, Emilie; Hardwigsen, Jean; Castellani, Paul; Perrier, Hervé; Bourlière, Marc

    2016-06-18

    Therapeutic management of hepatocellular carcinoma (HCC) is quite complex owing to the underlying cirrhosis and portal vein hypertension. Different scores or classification systems based on liver function and tumoral stages have been published in the recent years. If none of them is currently "universally" recognized, the Barcelona Clinic Liver Cancer (BCLC) staging system has become the reference classification system in Western countries. Based on a robust treatment algorithm associated with stage stratification, it relies on a high level of evidence. However, BCLC stage B and C HCC include a broad spectrum of tumors but are only matched with a single therapeutic option. Some experts have thus suggested to extend the indications for surgery or for transarterial chemoembolization. In clinical practice, many patients are already treated beyond the scope of recommendations. Additional alternative prognostic scores that could be applied to any therapeutic modality have been recently proposed. They could represent complementary tools to the BCLC staging system and improve the stratification of HCC patients enrolled in clinical trials, as illustrated by the NIACE score. Prospective studies are needed to compare these scores and refine their role in the decision making process. PMID:27330679

  7. Predictive Value of Tokuhashi Scoring Systems in Spinal Metastases, Focusing on Various Primary Tumor Groups

    DEFF Research Database (Denmark)

    Wang, Miao; Bünger, Cody; Haisheng, Li;

    2012-01-01

    and revised it in 2005 to a total sum of 15 points. There is a lack of knowledge about the specific predictive value of those scoring systems in patients with spinal metastases from a variety of cancer groups. METHODS: We included 448 patients with vertebral metastases who underwent surgical treatment during...... November 1992 to November 2009 in Aarhus University Hospital NBG. Data were retrieved from Aarhus Metastases Database. Scores based on T12 and T15 were calculated prospectively for each patient. We divided all the patients into different groups dictated by the site of their primary tumor. Predictive value...

  8. Technical feasibility and validation of a coronary artery calcium scoring system using CT coronary angiography images

    Energy Technology Data Exchange (ETDEWEB)

    Pavitt, Christopher W. [Royal Brompton Hospital, Department of Cardiology, London (United Kingdom); Royal Brompton Hospital, Department of Radiology, London (United Kingdom); Harron, Katie [Institute of Child Health, UCL, Centre for Paediatric Epidemiology and Biostatistics, London (United Kingdom); Lindsay, Alistair C.; Ray, Robin [Royal Brompton Hospital, Department of Cardiology, London (United Kingdom); Zielke, Sayeh; Rubens, Michael B. [Royal Brompton Hospital, Department of Radiology, London (United Kingdom); Gordon, Daniel [Royal Marsden Hospital, Department of Physics, London (United Kingdom); Padley, Simon P. [Royal Brompton Hospital, Department of Radiology, London (United Kingdom); Imperial College, Faculty of Medicine, London (United Kingdom); Nicol, Edward D. [Royal Brompton Hospital, Department of Cardiology, London (United Kingdom); Royal Brompton Hospital, Department of Radiology, London (United Kingdom); Imperial College, Faculty of Medicine, London (United Kingdom)

    2016-05-15

    We validate a novel CT coronary angiography (CCTA) coronary calcium scoring system. Calcium was quantified on CCTA images using a new patient-specific attenuation threshold: mean + 2SD of intra-coronary contrast density (HU). Using 335 patient data sets a conversion factor (CF) for predicting CACS from CCTA scores (CCTAS) was derived and validated in a separate cohort (n = 168). Bland-Altman analysis and weighted kappa for MESA centiles and Agatston risk groupings were calculated. Multivariable linear regression yielded a CF: CACS = (1.185 x CCTAS) + (0.002 x CCTAS x attenuation threshold). When applied to CCTA data sets there was excellent correlation (r = 0.95; p < 0.0001) and agreement (mean difference -10.4 [95 % limits of agreement -258.9 to 238.1]) with traditional calcium scores. Agreement was better for calcium scores below 500; however, MESA percentile agreement was better for high risk patients. Risk stratification was excellent (Agatston groups k = 0.88 and MESA centiles k = 0.91). Eliminating the dedicated CACS scan decreased patient radiation exposure by approximately one-third. CCTA calcium scores can accurately predict CACS using a simple, individualized, semiautomated approach reducing acquisition time and radiation exposure when evaluating patients for CAD. This method is not affected by the ROI location, imaging protocol, or tube voltage strengthening its clinical applicability. (orig.)

  9. Technical feasibility and validation of a coronary artery calcium scoring system using CT coronary angiography images

    International Nuclear Information System (INIS)

    We validate a novel CT coronary angiography (CCTA) coronary calcium scoring system. Calcium was quantified on CCTA images using a new patient-specific attenuation threshold: mean + 2SD of intra-coronary contrast density (HU). Using 335 patient data sets a conversion factor (CF) for predicting CACS from CCTA scores (CCTAS) was derived and validated in a separate cohort (n = 168). Bland-Altman analysis and weighted kappa for MESA centiles and Agatston risk groupings were calculated. Multivariable linear regression yielded a CF: CACS = (1.185 x CCTAS) + (0.002 x CCTAS x attenuation threshold). When applied to CCTA data sets there was excellent correlation (r = 0.95; p < 0.0001) and agreement (mean difference -10.4 [95 % limits of agreement -258.9 to 238.1]) with traditional calcium scores. Agreement was better for calcium scores below 500; however, MESA percentile agreement was better for high risk patients. Risk stratification was excellent (Agatston groups k = 0.88 and MESA centiles k = 0.91). Eliminating the dedicated CACS scan decreased patient radiation exposure by approximately one-third. CCTA calcium scores can accurately predict CACS using a simple, individualized, semiautomated approach reducing acquisition time and radiation exposure when evaluating patients for CAD. This method is not affected by the ROI location, imaging protocol, or tube voltage strengthening its clinical applicability. (orig.)

  10. Chromosome painting in biological dosimetry: Semi-automatic system to score stable chromosome aberrations

    International Nuclear Information System (INIS)

    From the beginning of the description of the procedure of chromosome painting by fluorescence in situ hybridization (FISH), it was thought its possible application to score induced chromosomal aberrations in radiation exposition. With chromosome painting it is possible to detect changes between chromosomes that has been validated in radiation exposition. Translocation scoring by FISH, contrarily to the unstable dicentrics, mainly detect stable chromosome aberrations that do not disappear, it allows the capability of quantify delayed acute expositions or chronic cumulative expositions. The large number of cells that have to be analyzed for high accuracy, specially when dealing with low radiation doses, makes it almost imperative to use an automatic analysis system. After validate translocation scoring by FISH in our, we have evaluated the ability and sensitivity to detect chromosomal aberrations by chromosome using different paint probes used, showing that any combination of paint probes can be used to score induced chromosomal aberrations. Our group has developed a FISH analysis that is currently being adapted for translocation scoring analysis. It includes systematic error correction and internal control probes. The performance tests carried out show that 9,000 cells can be analyzed in 10 hr. using a Sparc 4/370. Although with a faster computer, a higher throughput is expected, for large population screening or very low radiation doses, this performance still has to be improved. (author)

  11. New scoring system for intra-abdominal injury diagnosis after blunt trauma

    Directory of Open Access Journals (Sweden)

    Shojaee Majid

    2014-02-01

    Full Text Available 【Abstract】Objective: An accurate scoring system for intra-abdominal injury (IAI based on clinical manifestation and examination may decrease unnecessary CT scans, save time, and reduce healthcare cost. This study is designed to provide a new scoring system for a better diagno- sis of IAI after blunt trauma. Methods: This prospective observational study was performed from April 2011 to October 2012 on patients aged above 18 years and suspected with blunt abdominal trauma (BAT admitted to the emergency department (ED of Imam Hussein Hospital and Shohadaye Hafte Tir Hospital. All patients were assessed and treated based on Advanced Trauma Life Support and ED protocol. Diagnosis was done according to CT scan findings, which was considered as the gold standard. Data were gathered based on patient's history, physical exam, ultrasound and CT scan findings by a general practitioner who was not blind to this study. Chisquare test and logistic regression were done. Factors with significant relationship with CT scan were imported in multivariate regression models, where a coefficient (β was given based on the contribution of each of them. Scoring system was developed based on the obtained total βof each factor. Results: Altogether 261 patients (80.1% male were enrolled (48 cases of IAI. A 24-point blunt abdominal trauma scoring system (BATSS was developed. Patients were divided into three groups including low (score<8, moderate (8≤score<12 and high risk (score≥12. In high risk group immediate laparotomy should be done, moderate group needs further assessments, and low risk group should be kept under observation. Low risk patients did not show positive CT-scans (specificity 100%. Conversely, all high risk patients had positive CT-scan findings (sensitivity 100%. The receiver operating characteristic curve indicated a close relationship between the results of CT scan and BATSS (sensitivity=99.3%. Conclusion: The present scoring system furnishes a

  12. Implementation of an Early Warning Scoring System to Identify Patients With Cancer at Risk for Deterioration.

    Science.gov (United States)

    Olsen, MiKaela; Mooney, Kathy; Evans, Ellen

    2016-08-01

    Early warning scoring systems are tools for nurses to help monitor their patients and improve how quickly a patient experiencing a sudden decline receives clinical care. Nurse leaders and frontline staff at a major academic medical center implemented a new early warning system that gives clear guidelines to nurses, nursing assistants, and other clinicians about vital-sign parameters and changes in patients' mental status. 
. PMID:27441509

  13. [The scoring and rating system for the estimation of the teaching efficiency in forensic medicine].

    Science.gov (United States)

    Buromskiĭ, I V; Kil'diushov, E M

    2012-01-01

    The authors developed a system of criteria for the evaluation of the results of education of forensic medical students based on the scoring and rating scale. The major requirements for the organization of academic activities are considered. It is emphasized that the compliance with these requirements is an indispensable prerequisite for the introduction of the above system in the training routine at the Department of Forensic Medicine.

  14. Hospital triage system for adult patients using an influenza-like illness scoring system during the 2009 pandemic--Mexico.

    Directory of Open Access Journals (Sweden)

    Eduardo Rodriguez-Noriega

    Full Text Available BACKGROUND: Pandemic influenza A (H1N1 virus emerged during 2009. To help clinicians triage adults with acute respiratory illness, a scoring system for influenza-like illness (ILI was implemented at Hospital Civil de Guadalajara, Mexico. METHODS: A medical history, laboratory and radiology results were collected on emergency room (ER patients with acute respiratory illness to calculate an ILI-score. Patients were evaluated for admission by their ILI-score and clinicians' assessment of risk for developing complications. Nasal and throat swabs were collected from intermediate and high-risk patients for influenza testing by RT-PCR. The disposition and ILI-score of those oseltamivir-treated versus untreated, clinical characteristics of 2009 pandemic influenza A (H1N1 patients versus test-negative patients were compared by Pearson's Chi(2, Fisher's Exact, and Wilcoxon rank-sum tests. RESULTS: Of 1840 ER patients, 230 were initially hospitalized (mean ILI-score = 15, and the rest were discharged, including 286 ambulatory patients given oseltamivir (median ILI-score = 11, and 1324 untreated (median ILI-score = 5. Fourteen (1% untreated patients returned, and 3 were hospitalized on oseltamivir (median ILI-score = 19. Of 371 patients tested by RT-PCR, 104 (28% had pandemic influenza and 42 (11% had seasonal influenza A detected. Twenty (91% of 22 imaged hospitalized pandemic influenza patients had bilateral infiltrates compared to 23 (38% of 61 imaged hospital test-negative patients (p<0.001. One patient with confirmed pandemic influenza presented 6 days after symptom onset, required mechanical ventilation, and died. CONCLUSIONS: The triaging system that used an ILI-score complimented clinicians' judgment of who needed oseltamivir and inpatient care and helped hospital staff manage a surge in demand for services.

  15. Bender-gradual scoring system: performance of Brazilian and Peruvian children.

    Science.gov (United States)

    dos Santos, Acácia Aparecida Angeli; Noronha, Ana Paula Porto; Rueda, Fabián Javier Marín; Segovia, José Livia

    2014-06-01

    This is a transcultural study of a sample of Peruvian and Brazilian children using the Bender-Gradual Scoring System (B-SPG), which considers shape distortion as the only aspect to be analyzed, assuming that perceptual-motor maturity is independent of cultural context. The study verified that the scoring system has psychometric qualities such that it may be applied in another country. The sample consisted of 231 children, ages 6 to 10 yr., 108 from different districts of the province Lima in Peru, and 123 children from three states in Brazil. During test application, the figures were projected to children in groups. Scoring the protocols for errors was conducted by psychologists experienced in interpreting and correcting the Bender-SPG, who rigorously followed instructions in Portuguese and Spanish. The results obtained with Differential Item Functioning (DIF) analysis indicated that Figures 1 and 4 presented DIF, one favoring Brazilian children and the other Peruvian children. Thus, it was concluded that the overall scores did not favor either population and the Bender-SPG could be used to evaluate perceptual-motor maturity in both countries.

  16. A Score Function for Optimizing the Cycle-Life of Battery-Powered Embedded Systems

    DEFF Research Database (Denmark)

    Wognsen, Erik Ramsgaard; Haverkort, Boudewijn; Jongerden, Marijn;

    2015-01-01

    An ever increasing share of embedded systems is powered by rechargeable batteries. These batteries deteriorate with the number of charge/discharge cycles they are subjected to, the so-called cycle life. In this paper, we propose the wear score function to compare and evaluate the relative impact...... of usage (charge and discharge) profiles on cycle life. The wear score function can not only be used to rank different usage profiles, these rankings can also be used as a criterion for optimizing the overall lifetime of a battery-powered system. We perform such an optimization on a nano-satellite case...... study provided by the company GomSpace. The scheduling of the system is modelled as a network of (stochastic) weighted timed games. In a stochastic setting, exact optimization is very expensive. However, the recently introduced Uppaal Stratego tool combines symbolic synthesis with statistical model...

  17. Comparison of Existing Clinical Scoring Systems in Predicting Severity and Prognoses of Hyperlipidemic Acute Pancreatitis in Chinese Patients

    OpenAIRE

    Qiu, Lei; Sun, Rui Qing; Jia, Rong Rong; Ma, Xiu Ying; Cheng, Li; Tang, Mao Chun; Zhao, Yan

    2015-01-01

    Abstract It is important to identify the severity of acute pancreatitis (AP) in the early course of the disease. Clinical scoring systems may be helpful to predict the prognosis of patients with early AP; however, few analysts have forecast the accuracy of scoring systems for the prognosis in hyperlipidemic acute pancreatitis (HLAP). The purpose of this study was to summarize the clinical characteristics of HLAP and compare the accuracy of conventional scoring systems in predicting the progno...

  18. Predicting hospital-acquired infections by scoring system with simple parameters.

    Directory of Open Access Journals (Sweden)

    Ying-Jui Chang

    Full Text Available BACKGROUND: Hospital-acquired infections (HAI are associated with increased attributable morbidity, mortality, prolonged hospitalization, and economic costs. A simple, reliable prediction model for HAI has great clinical relevance. The objective of this study is to develop a scoring system to predict HAI that was derived from Logistic Regression (LR and validated by Artificial Neural Networks (ANN simultaneously. METHODOLOGY/PRINCIPAL FINDINGS: A total of 476 patients from all the 806 HAI inpatients were included for the study between 2004 and 2005. A sample of 1,376 non-HAI inpatients was randomly drawn from all the admitted patients in the same period of time as the control group. External validation of 2,500 patients was abstracted from another academic teaching center. Sixteen variables were extracted from the Electronic Health Records (EHR and fed into ANN and LR models. With stepwise selection, the following seven variables were identified by LR models as statistically significant: Foley catheterization, central venous catheterization, arterial line, nasogastric tube, hemodialysis, stress ulcer prophylaxes and systemic glucocorticosteroids. Both ANN and LR models displayed excellent discrimination (area under the receiver operating characteristic curve [AUC]: 0.964 versus 0.969, p = 0.507 to identify infection in internal validation. During external validation, high AUC was obtained from both models (AUC: 0.850 versus 0.870, p = 0.447. The scoring system also performed extremely well in the internal (AUC: 0.965 and external (AUC: 0.871 validations. CONCLUSIONS: We developed a scoring system to predict HAI with simple parameters validated with ANN and LR models. Armed with this scoring system, infectious disease specialists can more efficiently identify patients at high risk for HAI during hospitalization. Further, using parameters either by observation of medical devices used or data obtained from EHR also provided good prediction

  19. Retrospective Evaluation of New Chinese Diagnostic Scoring System for Disseminated Intravascular Coagulation.

    Directory of Open Access Journals (Sweden)

    Manzhi Wang

    Full Text Available To retrospectively validate the new Chinese DIC scoring system (CDSS.This study retrospectively collected the information of 619 patients (371 cases with non-hematologic malignancies, 248 cases with hematologic malignancies who suspected of DIC in Wuhan Union Hospital during 2013-4 to 2014-6. We validated CDSS by comparing it with three leading scoring systems, from International Society on Thrombosis and Haemostasis (ISTH, Japanese Association for Acute Medicine (JAAM and Japanese Ministry of Health and Welfare (JMHW, and evaluated its prognostic value by 28 days mortality, APACHE II and SOFA score.In non-hematologic malignancies, CDSS was more specific than JAAM (72.55% vs. 50.49%, p<0.05 and more sensitive than ISTH (77.07% vs. 62.03%, p<0.05. In hematologic malignancies, the area under the ROC curve of CDSS was larger than ISTH and JMHW (0.933 vs. 0.889, p<0.01 with ISTH, 0.944 vs. 0.845, p<0.01 with JMHW. In addition, the 28-day mortality rate, SOFA scores, APACHE II scores of DIC patients diagnosed by CDSS were significantly greater than non-DIC (P <0.05.We are the first group to propose CDSS. It emphasized the values of the clinical manifestations, the rapidly declining platelet count, APTT in the diagnosis of DIC and used D-dimer as the fibrin-related maker. DIC with hematological malignancies was treated as a special part. In this study we can see that CDSS displayed an acceptable property for the diagnosis of DIC with appropriate sensitivity and specificity, and also had a good prognostic value for DIC patients.

  20. A new scoring system using multiple immunohistochemical markers for diagnosis of uterine smooth muscle tumors

    Science.gov (United States)

    Rath-Wolfson, Lea; Rosenblat, Yevgenia; Halpern, Marisa; Herbert, M; Hammel, I; Gal, Rivka; Leabu, M; Koren, Rumelia

    2006-01-01

    The diagnosis of uterine smooth muscle neoplasms by light microscopy is difficult. Multiple classification schemes have been proposed based on mitotic rate, nuclear atypia, and the presence or absence of necrosis. None of these classification systems has been entirely successful. This study was undertaken to evaluate the use of selected immunohistochemical and histochemical markers in differentiating these tumors, in addition to accepted morphologic criteria. Ten cases of each of the following: leiomyosarcomas (LMS), atypical leiomyomas (AL), cellular leiomyomas (CL) and usual leiomyomas (UL), were classically evaluated for histological diagnosis and were stained for Ki-67 (MIB-1), bcl-2 and p53 using monoclonal antibodies and the avidin-biotin peroxidase method, and argyrophilic nucleolar organizer region (AgNORs). The number of stained cells was counted in the most positively stained region in a 4 mm2 square cover glass mounted on each slide. The mean value was calculated for each group of tumors. The data for Ki-67 (MIB-1), bcl-2, p53 and AgNOR staining respectively, were significantly higher in LMS by comparison to UL, CL or AL. Because many singular cases had superimposed data being difficult to diagnose, a new scoring system for pathological evaluation was created. The results obtained by this scoring system suggest that immunohistochemical markers Ki-67 (MIB-1), bcl-2, p53 together with the AgNOR staining could be useful, by the scoring system, as an adjunct to the current accepted morphologic criteria in differentiating smooth muscle tumors of the uterus. PMID:16563231

  1. Prognostic scoring systems for mortality in intensive care units--the APACHE model.

    Science.gov (United States)

    Niewiński, Grzegorz; Starczewska, Małgorzata; Kański, Andrzej

    2014-01-01

    The APACHE (Acute Physiology and Chronic Health Evaluation) scoring system is time consuming. The mean time for introducing a patient's data to APACHE IV is 37.3 min. Nevertheless, statisticians have known for years that the higher the number of variables the mathematical model describes, the more accurate the model. Because of the necessity of gathering data over a 24-hour period and of determining one cause for ICU admission, the system is troublesome and prone to mistakes. The evolution of the APACHE scoring system is an example of unfulfilled hopes for accurately estimating the risk of death for patients admitted to the ICU; satisfactory prognostic effects resulting from the use of APACHE II and III have been recently studied in patients undergoing liver transplantations. Because no increase in the predictive properties of successive versions has been observed, the search for other solutions continues. The APACHE IV scoring system is helpful; however, its use without prepared spreadsheets is almost impractical. Therefore, although many years have passed since its original publication, APACHE II or its extension APACHE III is currently used in clinical practice.

  2. Hematological scoring system as an early diagnostic tool for neonatal sepsis

    Directory of Open Access Journals (Sweden)

    Fathia Meirina

    2015-11-01

    Full Text Available Background Sepsis was the leading cause of death in babies by 30%-50% in developing countries. Early diagnosis of neonatal sepsis is still a difficult problem because of clinical features are not specific. Blood culture is the gold standard, but it takes several days and is expensive. The hematological scoring system (HSS consists of hematologic parameters (leucocyte count, polymorphonuclear (PMN cells, degenerative changes, and platelet count for early diagnosis of neonatal sepsis. Objective To measure HSS as an early diagnostic tool for neonatal sepsis. Methods A cross sectional study was conducted in March to June 2013. Samples were collected by consecutive sampling. Fourty neonates suspected sepsis in neonatology unit H. Adam Malik Hospital, Medan, North Sumatera, underwent routine blood count, blood culture, and peripheral blood smear. Each hematologic parameters were analysed using the HSS of Rodwell et al. The hematologic parameters were total leucocyte count, total PMN cells, total PMN immature, I:T PMN ratio, I:M PMN ratio, degenerative changes, and platelet count. The total value revealed HSS score. Diagnostic study parameters were calculated. Results Ten of fourty neonates had sepsis based on blood culture results. The HSS score >4 had sensitivity 80%, specificity 90% with positive predictive value (PPV 73%, negative predictive value (NPV 93%, ROC curve showed cut off point 0.902 (95% CI 0.803 to 1.0. Conclusion Score HSS >4 could be used as an early diagnostic tool for neonatal sepsis.

  3. Advanced Nursing Directives: Integrating Validated Clinical Scoring Systems into Nursing Care in the Pediatric Emergency Department

    Directory of Open Access Journals (Sweden)

    Erin Kate deForest

    2012-01-01

    Full Text Available In an effort to improve the quality and flow of care provided to children presenting to the emergency department the implementation of nurse-initiated protocols is on the rise. We review the current literature on nurse-initiated protocols, validated emergency department clinical scoring systems, and the merging of the two to create Advanced Nursing Directives (ANDs. The process of developing a clinical pathway for children presenting to our pediatric emergency department (PED with suspected appendicitis will be used to demonstrate the successful integration of validated clinical scoring systems into practice through the use of Advanced Nursing Directives. Finally, examples of 2 other Advanced Nursing Directives for common clinical PED presentations will be provided.

  4. Evaluation of day one embryo quality and IVF outcome – a comparison of two scoring systems

    Directory of Open Access Journals (Sweden)

    Svobodova Magda

    2009-02-01

    Full Text Available Abstract Background The aim of our retrospective study was to compare the clinical usefulness of two non-invasive embryo scoring systems based either on a simplified pronuclear morphology of the zygote or on early cleavage rate, as well as their combination, for the selection of embryos with the best implantation potential in embryo transfer (ET. Methods Over a period of five years, the quality of 2708 embryos from 364 IVF cycles in women under the age of 39 years was assessed using these scoring systems in a university assisted reproduction centre. ET was always performed on day 3 of cultivation. The outcome of ETs of 702 embryos scored in the respective systems or their combination was retrospectively analyzed in terms of biochemical (bPR and clinical pregnancy rates (cPR and implantation rate (IR. Mann-Whitney U test and t-test for differences between relative values were used, p Results There was no difference in outcome parameters in 109 cycles where only Pattern "0" zygotes, according to our simplified pronuclear morphology classification, were transferred and 140 cycles where only "other" pattern zygotes were transferred, regardless of their cleavage rate. On the contrary, significantly greater cPR and IR (p = 0.003 and p = 0.006, respectively were achieved in 120 cycles where only early cleavage (EC embryos were transferred compared with 152 cycles where only non early cleavage (NEC embryos were transferred regardless of their pronuclear morphology. The best outcome in terms of cPR (56% and IR (43% was found in 50 cycles when Pattern "0" and EC embryos only were used for transfer. Conclusion The results indicate that early cleavage is a better independent marker of implantation potential than zygote morphology. The best outcome can be achieved if both embryo scoring systems are used jointly and the embryo is classified as EC and Pattern "0".

  5. A Clinical Scoring System to Predict the Development of Bronchopulmonary Dysplasia

    OpenAIRE

    Gürsoy, Tuğba; Hayran, Mutlu; Derin, Hatice; Ovalı, Fahri

    2015-01-01

    ObjectiveThis study aims to develop a scoring system for the prediction of bronchopulmonary dysplasia (BPD). MethodsMedical records of 652 infants whose gestational age and birth weight were below 32 weeks and 1,500g, respectively, and who survived beyond 28th postnatal day were reviewed retrospectively. Logistic regression methods were used to determine the clinical and demographic risk factors within the first 72 hours of life associated with BPD, as well as the weights of these factors on ...

  6. Hematological scoring system as an early diagnostic tool for neonatal sepsis

    OpenAIRE

    Fathia Meirina; Bidasari Lubis; Tiangsa Sembiring; Nelly Rosdiana; Olga R. Siregar

    2015-01-01

    Background Sepsis was the leading cause of death in babies by 30%-50% in developing countries. Early diagnosis of neonatal sepsis is still a difficult problem because of clinical features are not specific. Blood culture is the gold standard, but it takes several days and is expensive. The hematological scoring system (HSS) consists of hematologic parameters (leucocyte count, polymorphonuclear (PMN) cells, degenerative changes, and platelet count) for early diagnosis of neonatal sepsis. Ob...

  7. Hematological scoring system(HSS)sebagai alat uji diagnostik dini sepsis pada neonatus

    OpenAIRE

    Meirina, Fathia

    2015-01-01

    Background. Sepsis was the leading cause of death in babies by 30%-50% in developing countries. Early diagnosis of neonatal sepsis was still a difficult problem because of clinical features were not specific. Blood culture was the gold standard, but it took several days and expensive. The hematological scoring system (HSS) consist of hematologic parameters (leucocyte, polymorphonuclear (PMN), degenerative changes, and platelet count) for early diagnosis of neonatal sepsis. Objective. To de...

  8. Comparison of severity of illness scoring systems in the prediction of hospital mortality in severe sepsis and septic shock

    Directory of Open Access Journals (Sweden)

    Crowe Colleen

    2010-01-01

    Full Text Available Background : New scoring systems, including the Rapid Emergency Medicine Score (REMS, the Mortality in Emergency Department Sepsis (MEDS score, and the confusion, urea nitrogen, respiratory rate, blood pressure, 65 years and older (CURB-65 score, have been developed for emergency department (ED use in various patient populations. Increasing use of early goal directed therapy (EGDT for the emergent treatment of sepsis introduces a growing population of patients in which the accuracy of these scoring systems has not been widely examined. Objectives : To evaluate the ability of the REMS, MEDS score, and CURB-65 score to predict mortality in septic patients treated with modified EGDT. Materials and Methods : Secondary analysis of data from prospectively identified patients treated with modified EGDT in a large tertiary care suburban community hospital with over 85,000 ED visits annually and 700 inpatient beds, from May 2007 through May 2008. We included all patients with severe sepsis or septic shock, who were treated with our modified EGDT protocol. Our major outcome was in-hospital mortality. The performance of the scores was compared by area under the ROC curves (AUCs. Results : A total of 216 patients with severe sepsis or septic shock were treated with modified EGDT during the study period. Overall mortality was 32.9%. Calculated AUCs were 0.74 [95% confidence interval (CI: 0.67-0.81] for the MEDS score, 0.62 (95% CI: 0.54-0.69 for the REMS, and 0.59 (95% CI: 0.51-0.67 for the CURB-65 score. Conclusion : We found that all three ED-based systems for scoring severity of illness had low to moderate predictive capability. The MEDS score demonstrated the largest AUC of the studied scoring systems for the outcome of mortality, although the CIs on point estimates of the AUC of the REMS and CURB-65 scores all overlap.

  9. Intelligibility in microbial complex systems: Wittgenstein and the score of life.

    Science.gov (United States)

    Baquero, Fernando; Moya, Andrés

    2012-01-01

    Knowledge in microbiology is reaching an extreme level of diversification and complexity, which paradoxically results in a strong reduction in the intelligibility of microbial life. In our days, the "score of life" metaphor is more accurate to express the complexity of living systems than the classic "book of life." Music and life can be represented at lower hierarchical levels by music scores and genomic sequences, and such representations have a generational influence in the reproduction of music and life. If music can be considered as a representation of life, such representation remains as unthinkable as life itself. The analysis of scores and genomic sequences might provide mechanistic, phylogenetic, and evolutionary insights into music and life, but not about their real dynamics and nature, which is still maintained unthinkable, as was proposed by Wittgenstein. As complex systems, life or music is composed by thinkable and only showable parts, and a strategy of half-thinking, half-seeing is needed to expand knowledge. Complex models for complex systems, based on experiences on trans-hierarchical integrations, should be developed in order to provide a mixture of legibility and imageability of biological processes, which should lead to higher levels of intelligibility of microbial life.

  10. Comparison of a classical with a highly formularized body condition scoring system for dairy cattle.

    Science.gov (United States)

    Isensee, A; Leiber, F; Bieber, A; Spengler, A; Ivemeyer, S; Maurer, V; Klocke, P

    2014-12-01

    Body condition scoring is a common tool to assess the subcutaneous fat reserves of dairy cows. Because of its subjectivity, which causes limits in repeatability, it is often discussed controversially. Aim of the current study was to evaluate the impact of considering the cows overall appearance on the scoring process and on the validity of the results. Therefore, two different methods to reveal body condition scores (BCS), 'independent BCS' (iBCS) and 'dependent BCS' (dBCS), were used to assess 1111 Swiss Brown Cattle. The iBCS and the dBCS systems were both working with the same flowchart with a decision tree structure for visual and palpatory assessment using a scale from 2 to 5 with increment units of 0.25. The iBCS was created strictly complying with the defined frames of the decision tree structure. The system was chosen due to its formularized approach to reduce the influence of subjective impressions. By contrast, the dBCS system, which was in line with common practice, had a more open approach, where - besides the decision tree - the overall impression of the cow's physical appearance was taken into account for generating the final score. Ultrasound measurement of the back fat thickness (BFT) was applied as a validation method. The dBCS turned out to be the better predictor of BFT, explaining 67.3% of the variance. The iBCS was only able to explain 47.3% of the BFT variance. Within the whole data set, only 31.3% of the animals received identical dBCS and iBCS. The pin bone region caused the most deviations between dBCS and iBCS, but also assessing the pelvis line, the hook bones and the ligaments led to divergences in around 20% of the scored animals. The study showed that during the assessment of body condition a strict adherence to a decision tree is a possible source of inexact classifications. Some body regions, especially the pin bones, proved to be particularly challenging for scoring due to difficulties in assessing them. All the more, the inclusion

  11. Similar performance of Brasfield and Wisconsin scoring systems in young children with cystic fibrosis

    Energy Technology Data Exchange (ETDEWEB)

    Cleveland, Robert H.; Stamoulis, Catherine [Boston Children' s Hospital, Harvard Medical School, Department of Radiology, Boston, MA (United States); Sawicki, Gregory S. [Boston Children' s Hospital, Harvard Medical School, Division of Respiratory Diseases, Department of Medicine, Boston, MA (United States)

    2015-10-15

    To assess the severity of lung disease in cystic fibrosis (CF), scoring systems based on chest radiographs (CXRs), CT and MRI have been used extensively, although primarily in research settings rather than for clinical purposes. It has recently been shown that those based on CXRs (primarily the Brasfield and Wisconsin systems) are as sensitive and valid as those based on CT. The reproducibility and correlation of both systems to pulmonary function tests (PFTs) were recently investigated and were found to be statistically identical. However, the relative performance of these systems has not been specifically assessed in children younger than 5 years old with mild lung disease, a critical age range in which PFTs is rarely performed. To investigate and compare the performance of the Brasfield and Wisconsin systems in children 0-5 years old with predominantly mild lung disease. Fifty-five patients 0-5 years old with 105 CXRs were included in the study. Given that the goal was to compare system performance in mild disease, only the first two CXRs from each patient were included (all but five patients had two images). When only one image was available in the target age range, it only was included. Agreement between the Brasfield and Wisconsin systems was assessed using a 2X2 contingency table assuming binary classification of CF lung disease using CXR scoring systems (mild vs. non-mild). In the absence of PFTs or another external gold standard for comparison, the Wisconsin system was used as an arbitrary gold standard against which the Brasfield was compared. Correlation between the two systems was assessed via a concordance correlation coefficient (CCC) for repeated measures. Scores were rated as mild or non-mild based on published numerical cutoffs for each system. The systems agreed on 89/105 (85%) and disagreed on 16/105 (15%) of the CXRs. Agreement between the two systems was statistically significant (P < 0.001). Relative sensitivity and specificity of the

  12. Similar performance of Brasfield and Wisconsin scoring systems in young children with cystic fibrosis

    International Nuclear Information System (INIS)

    To assess the severity of lung disease in cystic fibrosis (CF), scoring systems based on chest radiographs (CXRs), CT and MRI have been used extensively, although primarily in research settings rather than for clinical purposes. It has recently been shown that those based on CXRs (primarily the Brasfield and Wisconsin systems) are as sensitive and valid as those based on CT. The reproducibility and correlation of both systems to pulmonary function tests (PFTs) were recently investigated and were found to be statistically identical. However, the relative performance of these systems has not been specifically assessed in children younger than 5 years old with mild lung disease, a critical age range in which PFTs is rarely performed. To investigate and compare the performance of the Brasfield and Wisconsin systems in children 0-5 years old with predominantly mild lung disease. Fifty-five patients 0-5 years old with 105 CXRs were included in the study. Given that the goal was to compare system performance in mild disease, only the first two CXRs from each patient were included (all but five patients had two images). When only one image was available in the target age range, it only was included. Agreement between the Brasfield and Wisconsin systems was assessed using a 2X2 contingency table assuming binary classification of CF lung disease using CXR scoring systems (mild vs. non-mild). In the absence of PFTs or another external gold standard for comparison, the Wisconsin system was used as an arbitrary gold standard against which the Brasfield was compared. Correlation between the two systems was assessed via a concordance correlation coefficient (CCC) for repeated measures. Scores were rated as mild or non-mild based on published numerical cutoffs for each system. The systems agreed on 89/105 (85%) and disagreed on 16/105 (15%) of the CXRs. Agreement between the two systems was statistically significant (P < 0.001). Relative sensitivity and specificity of the

  13. Fecal-tagging CT colonography with structure-analysis electronic cleansing for detection of colorectal flat lesions

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Yonghua, E-mail: howardyonghua@gmail.com [Department of Radiology, Xuhui Central Hospital of Shanghai and China Academy of Sciences Shanghai Medical Center, 966 Huai Hai Central Road, Shanghai 200031 (China); Department of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016 (China); Cai, Wenli; Nappi, Janne; Yoshida, Hiro [Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 25 New Chardon Street 400C, Boston, MA 02114 (United States)

    2012-08-15

    Purpose: To evaluate the feasibility and sensitivity of the 3D-reading of fecal-tagging CT colonography (CTC) with a novel structure-analysis electronic cleansing (SAEC) in detecting colorectal flat lesions in comparison with a cleansed 3D reading with Viatronix V3D Colon system (V3D) and primary uncleansed 2D reading (2D). Materials and methods: Forty CTC cases with flat lesions were retrospectively observed. The Subjects from a multicenter clinical trial underwent cathartic bowel preparation with orally administrated barium-based fecal-tagging. Sixty-nine flat lesions were confirmed using colonoscopy and histopathology as a reference standard. The results from SAEC reading were compared with those of prospective V3D and 2D readings. Results: Overall detection sensitivity with SAEC was 52% (36/69), which was statistically higher than that of 32% (22/69) and 29% (20/69) with V3D and 2D readings, respectively (p < 0.05). The sensitivities in detecting not-on-fold flat lesions were 63% (24/38), 45% (17/38), and 42% (16/38) with SAEC, V3D, and 2D readings, respectively; whereas those of on-fold flat lesions were 39% (12/31), 16% (5/31), and 13% (4/31), respectively. None of the eight flat lesions (2-9 mm) at cecum was detected by any of the three reading methods. Excluding the flat lesions at cecum, the sensitivity with SAEC for detecting flat lesion {>=}4 mm increased to 84% (31/37). Conclusions: The fecal-tagging CTC with structure-analysis electronic cleansing could yield a high sensitivity for detecting flat lesions {>=}4 mm. The not-on-fold flat lesions were detected with higher sensitivity than on-fold flat lesions.

  14. A 'big five' scoring system for the item pool of the adjective check list.

    Science.gov (United States)

    FormyDuval, D L; Williams, J E; Patterson, D J; Fogle, E E

    1995-08-01

    The item pool of the Adjective Check List (ACL; Gough & Heilbrun, 1980) is widely used as a means of capturing the personal characteristics associated with various target groups (e.g., women vs. men, young adults vs. old adults). The purpose of this research was to develop a system for scoring the ACL items in terms of the five-factor model of personality. In Study 1, five groups of introductory psychology students served as judges, with each group of approximately 100 persons rating the 300 ACL items for one of the five factors. The ratings of each factor were highly reliable. When corrected for favorability, the intercorrelations among the five factors were quite low, as expected, except for the positive correlation of Openness and Extraversion. Good convergence was found between our ratings and the indicative and counterindicative items identified by John's (1989) graduate student judges. In Study 2, convergent validity was demonstrated between the five-factor scores obtained from self-descriptive ACLs and corresponding factor scores obtained from Costa and McCrae's NEO-PI-R and NEO-FFI instruments (Costa & McCrae, 1992). Data from earlier cross-cultural studies of gender and age stereotypes were rescored using the new ACL-FF system to illustrate its potential utility as a research tool. PMID:16367646

  15. Early warning scores: a sign of deterioration in patients and systems

    LENUS (Irish Health Repository)

    Fox, A

    2015-02-01

    The early warning score is a decision-making tool that has a simple design, yet its implementation in healthcare organisations is proving complex. This article reports the results of a survey that evaluated the nurses’ experiences of using the NEWS (National Early Warning Score) in an acute hospital in Ireland. Staff reported that the NEWS was easy to use, did not increase workload and enhanced their ability to identify deteriorating patients. However, they also identified problems related to doctors’ delayed response times, doctors lack of training in the use of the tool, and a failure by doctors to modify parameters for patients with chronic conditions. NEWS enhances nurses’ role in early detection of patient deterioration but delays in response times by doctors, exposes systematic flaws in healthcare. This suggests that it is not only an indicator of patient deterioration but also of deteriorating healthcare systems.

  16. A Psychometric Study of the Kinetic-House-Tree-Person Scoring System for People with Psychiatric Disorders in Taiwan

    Directory of Open Access Journals (Sweden)

    Chih-Ying Li

    2014-06-01

    Conclusion: The KHTP scoring system has acceptable construct validity, inter-rater reliability, and test–retest reliability. Because drawing tests have the advantage of expressing nonverbal characteristics, the scoring system should prove to be very useful for those who are unwilling or unable to communicate verbally. This study therefore provides valuable information for clinical application, particularly for the psychiatric rehabilitation professions.

  17. Comparison of the Qualitative and Developmental Scoring Systems for the Modified Version of the Bender-Gestalt Test.

    Science.gov (United States)

    Brannigan, Gary G.; Brunner, Nancy A.

    1993-01-01

    Examined two scoring systems for Modified Version of the Bender-Gestalt Test. Administered Bender-Gestalt and Otis-Lennon School Ability Test to 75 first-grade and 84 second-grade students. Both systems were significantly correlated with school ability. Results of tests for differences between correlations indicated that Qualitative Scoring System…

  18. Comparison of the Bender Gestalt Test for Both Black and White Brain-Damaged Patients Using Two Scoring Systems

    Science.gov (United States)

    Butler, Oliver T.; And Others

    1976-01-01

    This study tested for cultural bias in the Bender Visual Motor Gestalt Test. Subjects were 72 black and white patients diagnosed as either brain damaged or psychiatric. Bender protocols were scored by Pascal-Suttell and Hain systems. No race effect appeared except for the Pascal-Suttell system for which blacks scored significantly better. (Author)

  19. Clinical performance of two visual scoring systems in detecting and assessing activity status of occlusal caries in primary teeth

    DEFF Research Database (Denmark)

    Braga, M M; Ekstrand, K R; Martignon, S;

    2010-01-01

    This study aimed to compare the clinical performance of two sets of visual scoring criteria for detecting caries severity and assessing caries activity status in occlusal surfaces. Two visual scoring systems--the Nyvad criteria (NY) and the ICDAS-II including an adjunct system for lesion activity...

  20. The generic impact scoring system (GISS): a standardized tool to quantify the impacts of alien species.

    Science.gov (United States)

    Nentwig, Wolfgang; Bacher, Sven; Pyšek, Petr; Vilà, Montserrat; Kumschick, Sabrina

    2016-05-01

    Alien species can exert negative environmental and socio-economic impacts. Therefore, administrations from different sectors are trying to prevent further introductions, stop the spread of established species, and apply or develop programs to mitigate their impact, to contain the most harmful species, or to eradicate them if possible. Often it is not clear which of the numerous alien species are most important in terms of damage, and therefore, impact scoring systems have been developed to allow a comparison and thus prioritization of species. Here, we present the generic impact scoring system (GISS), which relies on published evidence of environmental and socio-economic impact of alien species. We developed a system of 12 impact categories, for environmental and socio-economic impact, comprising all kinds of impacts that an alien species may exert. In each category, the intensity of impact is quantified by a six-level scale ranging from 0 (no impact detectable) to 5 (the highest impact possible). Such an approach, where impacts are grouped based on mechanisms for environmental impacts and receiving sectors for socio-economy, allows for cross-taxa comparisons and prioritization of the most damaging species. The GISS is simple and transparent, can be conducted with limited funds, and can be applied to a large number of alien species across taxa and environments. Meanwhile, the system was applied to 349 alien animal and plant species. In a comparison with 22 other impact assessment methods, the combination of environmental and socio-economic impact, as well as the possibility of weighting and ranking of the scoring results make GISS the most broadly applicable system. PMID:27129597

  1. The Relationship of Scores on Elizur's Hostility System on the Rorschach to the Acting-Out Score on the Hand Test.

    Science.gov (United States)

    Martin, John D.; And Others

    1978-01-01

    The relationship between Elizur's Hostility Scoring on the Rorschach Test and the Acting-Out Score on the Hand Test was examined. Correlations between the two measures (using several scoring procedures) ranged from .40 to .64. (JKS)

  2. A recently developed MRI scoring system for hand osteoarthritis: its application in a clinical setting.

    Science.gov (United States)

    Ramonda, Roberta; Favero, Marta; Vio, Stefania; Lacognata, Carmelo; Frallonardo, Paola; Belluzzi, Elisa; Campana, Carla; Lorenzin, Mariagrazia; Ortolan, Augusta; Angelini, Federico; Piccoli, Antonio; Oliviero, Francesca; Punzi, Leonardo

    2016-08-01

    This study aimed to apply the recently proposed Oslo hand osteoarthritis magnetic resonance imaging (MRI) scoring system to evaluate MRI findings in a cohort of patients affected by long-standing erosive hand osteoarthritis (EHOA). Eleven female EHOA patients (median 59 [interquartile range 62-52] years, disease duration 9.5 [interquartile range 13-3.75] years) underwent MRI (1.5 T) of the dominant hand, and synovitis, bone marrow lesions (BMLs), joint space narrowing, osteophytes, cysts, malalignment, and erosions were scored using the Oslo scoring system. Intra- and inter-reader reliability were assessed. The patients also underwent X-ray examination, and bone features were evaluated using the same scoring system. Pain and tenderness were assessed during a physical examination. Spearman's non-parametric test was used to analyze the correlations between variables. MRI intra- and inter-reader reliability were found between good and moderate for many features. No statistical differences were found between the radiographs and MRI with regard to detection of JSN, malalignment, and bone erosions. Synovitis was detected in 39.8 % of the 80 joints examined (in a mild form in 80 %), erosions were found in 51.1 %, and BMLs were identified in 20.5 and 23.9 % at the distal and the proximal side, respectively. BMLs at both the proximal and distal ends were correlated with tender joints (BML distal p = 0.0013, BML proximal p = 0.012). The presence of synovitis was correlated with tenderness (p = 0.004) and erosions at both the distal and proximal joints (p = 0.004). The presence of erosions correlated with tender joints (p < 0.01) and the mean visual analog scale (VAS) score (distal p = 0.03, proximal p = 0.01). Synovitis and BMLs were correlated with clinical symptoms in our patients affected with long-standing EHOA. PMID:27236512

  3. Oxford NOTECHS II: a modified theatre team non-technical skills scoring system.

    Directory of Open Access Journals (Sweden)

    Eleanor R Robertson

    Full Text Available BACKGROUND: We previously developed and validated the Oxford NOTECHS rating system for evaluating the non-technical skills of an entire operating theatre team. Experience with the scale identified the need for greater discrimination between levels of performance within the normal range. We report here the development of a modified scale (Oxford NOTECHS II to facilitate this. The new measure uses an eight-point instead of a four point scale to measure each dimension of non-technical skills, and begins with a default rating of 6 for each element. We evaluated this new scale in 297 operations at five NHS sites in four surgical specialities. Measures of theatre process reliability (glitch count and compliance with the WHO surgical safety checklist were scored contemporaneously, and relationships with NOTECHS II scores explored. RESULTS: Mean team Oxford NOTECHS II scores was 73.39 (range 37-92. The means for surgical, anaesthetic and nursing sub-teams were 24.61 (IQR 23, 27; 24.22 (IQR 23, 26 and 24.55 (IQR 23, 26. Oxford NOTECHS II showed good inter-rater reliability between human factors and clinical observers in each of the four domains. Teams with high WHO compliance had higher mean Oxford NOTECHS II scores (74.5 than those with low compliance (71.1 (p = 0.010. We observed only a weak correlation between Oxford NOTECHS II scores and glitch count; r = -0.26 (95% CI -0.36 to -0.15. Oxford NOTECHS II scores did not vary significantly between 5 different hospital sites, but a significant difference was seen between specialities (p = 0.001. CONCLUSIONS: Oxford NOTECHS II provides good discrimination between teams while retaining reliability and correlation with other measures of teamwork performance, and is not confounded by technical performance. It is therefore suitable for combined use with a technical performance scale to provide a global description of operating theatre team performance.

  4. Acute Radiation Syndrome Severity Score System in Mouse Total-Body Irradiation Model.

    Science.gov (United States)

    Ossetrova, Natalia I; Ney, Patrick H; Condliffe, Donald P; Krasnopolsky, Katya; Hieber, Kevin P

    2016-08-01

    Radiation accidents or terrorist attacks can result in serious consequences for the civilian population and for military personnel responding to such emergencies. The early medical management situation requires quantitative indications for early initiation of cytokine therapy in individuals exposed to life-threatening radiation doses and effective triage tools for first responders in mass-casualty radiological incidents. Previously established animal (Mus musculus, Macaca mulatta) total-body irradiation (γ-exposure) models have evaluated a panel of radiation-responsive proteins that, together with peripheral blood cell counts, create a multiparametic dose-predictive algorithm with a threshold for detection of ~1 Gy from 1 to 7 d after exposure as well as demonstrate the acute radiation syndrome severity score systems created similar to the Medical Treatment Protocols for Radiation Accident Victims developed by Fliedner and colleagues. The authors present a further demonstration of the acute radiation sickness severity score system in a mouse (CD2F1, males) TBI model (1-14 Gy, Co γ-rays at 0.6 Gy min) based on multiple biodosimetric endpoints. This includes the acute radiation sickness severity Observational Grading System, survival rate, weight changes, temperature, peripheral blood cell counts and radiation-responsive protein expression profile: Flt-3 ligand, interleukin 6, granulocyte-colony stimulating factor, thrombopoietin, erythropoietin, and serum amyloid A. Results show that use of the multiple-parameter severity score system facilitates identification of animals requiring enhanced monitoring after irradiation and that proteomics are a complementary approach to conventional biodosimetry for early assessment of radiation exposure, enhancing accuracy and discrimination index for acute radiation sickness response categories and early prediction of outcome. PMID:27356057

  5. Comparison of discrimination and prognostic value of two US Doppler scoring systems in rheumatoid arthritis patients

    DEFF Research Database (Denmark)

    Ellegaard, Karen; Terslev, Lene; Christensen, Robin;

    2014-01-01

    OBJECTIVES: The aim of this paper is to investigate sensitivity to change (SRM), predictive validity and discriminative ability of a quantitative (QS) and a semi-quantitative (SQS) Doppler ultrasound scoring systems in patients with rheumatoid arthritis (RA) treated with anti-TNF-α therapy. METHODS......: RA patients with wrist joint affection treated with TNF-α inhibitor were followed for one year. The wrist was examined with Doppler before initiating therapy and after one year. DAS28 was determined at both visits. One person trained in the SQS system and one in the QS system evaluated the anonymised...... images. The SRM, predictive validity and discriminative ability for both systems were calculated using DAS28 as the measure of disease improvement. RESULTS: Fourty-six patients with RA (80% females) were included. The mean Doppler activity at baseline was QS:24.4% (SD=17.7%) and SQS:2.0 (SD=0...

  6. A modified scoring system to describe gross pathology in the rabbit model of tuberculosis

    Directory of Open Access Journals (Sweden)

    Osborne Jonathan

    2011-03-01

    Full Text Available Abstract Background The rabbit model is an ideal means to study the pathogenesis of tuberculosis due to its semblance to the disease in humans. We have previously described the results using a bronchoscopic route of infection with live bacilli as a reliable means of generating lung cavities in sensitized rabbits. The role of sensitization in the development of disease outcomes has been well established in several animal models. We have described here the varying gross pathology that result from lack of sensitization with heat-killed M. bovis prior to high-dose bronchoscopic infection with live bacilli. Results Rabbits lacking sensitization did not generate lung cavities, but instead formed solely a tuberculoid pneumonia that replaced the normal lung parenchyma in the area of infection. Extrapulmonary dissemination was seen in approximately equal frequency and distribution in both rabbit populations. Notable differences include the lack of intestinal lesions in non-sensitized rabbits likely due to the lack of ingestion of expectorated bacilli from cavitary lesions. The experiment also employed a modified scoring system developed initially in the primate model of tuberculosis to allow for the quantification of findings observed at necropsy. Conclusions To date, no such scoring system has been employed in the rabbit model to describe gross pathology. The quantitative methodology would allow for rapid comparative analyses and standardization of thoracic and extrapulmonary pathology that could be evaluated for statistical significance. The aim is to use such a scoring system as the foundation for all future rabbit studies describing gross pathology at all stages in TB pathogenesis.

  7. Evaluating clinical abdominal scoring system in predict- ing the necessity of laparotomy in blunt abdominal trauma

    Directory of Open Access Journals (Sweden)

    Erfantalab-Avini Peyman

    2011-06-01

    Full Text Available 【Abstract】 Objectives: Trauma is among the lead- ing causes of death. Medical management of blunt abdomi- nal trauma (BAT relies on judging patients for whom lap- arotomy is mandatory. This study aimed to determine BAT patients’ signs, as well as paraclinical data, and to clarify the accuracy, sensitivity, specificity, positive and negative predictive value of clinical abdominal scoring system (CASS, a new scoring system based on clinical signs, in predicting whether a BAT patient needs laparotomy or not. Methods: Totally 400 patients suspected of BAT that arrived at the emergency department of two university hos- pitals in Tehran from March 20, 2007 to March 19, 2009 were included in this study. They were evaluated for age, sex, type of trauma, systolic blood pressure, Glasgow coma scale (GCS, pulse rate, time of presentation after trauma, abdomi- nal clinical findings, respiratory rate, temperature, hemoglo- bin (Hb concentration, focused abdominal sonography in trauma (FAST and CASS. Results: Our measurements showed that CASS had an accuracy of 94%, sensitivity of 100%, specificity of 88%, positive predictive value of 90% and negative predictive value of 100% in determining the necessity of laparotomy in BAT patients. Moreover, in our analysis, systolic blood pressure, GCS, pulse rate, Hb concentration, time of presen- tation after trauma, abdominal clinical findings and FAST were also shown to be helpful in confirming the need for laparotomy (P<0.05. Conclusion: CASS is a promising scoring system in rapid detection of the need for laparotomy as well as in minimizing auxiliary expense for further evaluation in BAT patients, thus to promote the cost-benefit ratio and accu- racy of diagnosis. Key words: Abdominal injuries; Laparotomy; Patients; Wounds, nonpenetrating

  8. Electrocardiogram-based scoring system for predicting secondary pulmonary hypertension: A cross-sectional study

    OpenAIRE

    Pancholy, Samir Bipin; Palamaner Subash Shantha, Ghanshyam; Patel, Nimesh Kirit; Boruah, Pranjal; Nanavaty, Sukrut; Chandran, Sindu; Sethi, Arjinder; Sheth, Jignesh

    2014-01-01

    Objectives In this study, we have developed an electrocardiogram-based scoring system to predict secondary pulmonary hypertension. Design A cross-sectional study. Setting Single tertiary-care hospital in Scranton, Pennsylvania, USA. Participants Five hundred and fifty-two consecutive patients undergoing right heart catheterization between 2006 and 2009. Main outcome measures Surface electrocardiogram was assessed for R-wave in lead V1 ≥ 6mm, R-wave in V6 ≤ 3mm, S-wave in V6 ≥ 3mm, right atria...

  9. Expanded Koppitz Scoring System of the Bender Gestalt Visual-Motor Test for Adolescents: A Pilot Study.

    Science.gov (United States)

    Bolen, Larry M.; And Others

    1992-01-01

    Examined use of Bender Gestalt Visual-Motor Test with school-age adolescents over age 11. Mean error scores suggest that visual-motor development is not maturationally complete by age 11 years, 11 months. Suggests additional research focusing on extending normative sample or developing new scoring system for adolescents. (Author/NB)

  10. The Consistency between Human Raters and an Automated Essay Scoring System in Grading High School Students' English Writing

    Science.gov (United States)

    Tsai, Min-hsiu

    2012-01-01

    This study investigates the consistency between human raters and an automated essay scoring system in grading high school students' English compositions. A total of 923 essays from 23 classes of 12 senior high schools in Taiwan (Republic of China) were obtained and scored manually and electronically. The results show that the consistency between…

  11. The application of European system for cardiac operative risk evaluation II (EuroSCORE II and Society of Thoracic Surgeons (STS risk-score for risk stratification in Indian patients undergoing cardiac surgery

    Directory of Open Access Journals (Sweden)

    Deepak Borde

    2013-01-01

    Full Text Available Aims and Objectives: To validate European system for cardiac operative risk evaluation II (EuroSCORE II and Society of Thoracic Surgeons (STS risk-score for predicting mortality and STS risk-score for predicting morbidity in Indian patients after cardiac surgery. Materials and Methods: EuroSCORE II and STS risk-scores were obtained pre-operatively for 498 consecutive patients. The patients were followed for mortality and various morbidities. The calibration of the scoring systems was assessed using Hosmer-Lemeshow test. The discriminative capacity was estimated by area under receiver operating characteristic (ROC curves. Results: The mortality was 1.6%. For EuroSCORE II and STS risk-score C-statics of 5.43 and 6.11 were obtained indicating satisfactory model fit for both the scores. Area under ROC was 0.69 and 0.65 for EuroSCORE II and STS risk-score with P values of 0.068 and 0.15, respectively, indicating poor discriminatory power. Good fit and discrimination was obtained for renal failure, long-stay in hospital, prolonged ventilator support and deep sternal wound infection but the scores failed in predicting risk of reoperation and stroke. Mortality risk was correctly estimated in low ( 5% patients by both scoring systems. Conclusions: EuroSCORE II and STS risk-scores have satisfactory calibration power in Indian patients but their discriminatory power is poor. Mortality risk was over-estimated by both the scoring systems in high-risk patients. The present study highlights the need for forming a national database and formulating risk stratification tools to provide better quality care to cardiac surgical patients in India.

  12. MR score system on spatium perilymphaticum gadolinium opacification and its application for diagnosis of Meniere's disease

    International Nuclear Information System (INIS)

    Objective: To propose a MR scoring methods for spatium perilymphaticum gadolinium opacification and explore the value of their diagnosis of Meniere's disease. Methods: Fifty-one asymptomatic and 65 symptomatic patients with Meniere's disease were enrolled in this study. MR imaging of spatium perilymphaticum after intratypanic gadolinium injection were analyzed with following scoring method. (1) Semicircular canal not visualized equal to score 0; some visualized equal score 1; full visualized equal score 2.(2)There were high-signal and low-signal in the vestibule, low-signal areas above the lateral semicircular canal plane equal score 6; low signal areas down to lateral semicircular canal plane equal score 3; no higher signal in the vestibule area equal score 0. (3) Basal turn of cochlea: full visualized equal score 3; part visualized equal score 2; scala vestibule of basal turn smaller than scala tympani equal score 1 regardless of full or visualized in basal turn; no visualized equal score 0. Medial turn of cochlea: full visualized equal score 2; part visualized equal score 1; no visualized equal score 0. Apical turn of cochlea: visualized equal score 1; no visualized equal score 0. One radiologist scored all cases with double blind. SPSS 17.0 software was used to conduct multiple independent-samples nonparametric tests, multivariate Logistic regression, and ROC curve analysis. Evaluate the sensitivity and specificity for diagnosis of Meniere's disease with the scoring system. Results: (1) Meniere's disease summation score 0 to 12, median 9 (quarter spacing 4.5); no symptoms group summation score 15 to 18,median 17 (quarter spacing 3), two group differences has statistics significance (Wilcoxon rank and inspection U=-9.118, P=0.00). (2) Based on summation score for the diagnosis of Meniere's disease, tangent point was 14.5, Youden index 0.969, specificity 100.0%, sensitivity 96.9%.(3) Let cochlear, vestibular, semicircular canal scoring

  13. A critical appraisal of radiographic scoring systems for assessment of juvenile idiopathic arthritis

    Energy Technology Data Exchange (ETDEWEB)

    Doria, Andrea S.; Babyn, Paul S. [The Hospital for Sick Children, Department of Diagnostic Imaging, Toronto, Ontario (Canada); University of Toronto, Department of Medical Imaging, Toronto, Ontario (Canada); Feldman, Brian [The Hospital for Sick Children, Department of Rheumatology, Toronto, Ontario (Canada); University of Toronto, Department of Population Health Sciences, Toronto (Canada)

    2006-08-15

    Assessing structural damage to joints over time is essential for evaluating the effectiveness of therapeutic interventions for patients with inflammatory arthritis. Although radiography is able to quantify joint damage, the changes found with conventional radiography early in the disease course are nonspecific, and late radiographic changes are often irreversible. Although many clinical trials on drug development for children still use radiographic scales as endpoints for the study, more specific therapies have been developed for juvenile idiopathic arthritis (JIA) that would enable imaging to ''fine-tune'' patients to placement into specific treatment algorithms. As a result, new imaging scales to identify early abnormalities are clearly needed. Many pediatric rheumatology centers around the world persistently apply adult-designed radiographic scoring systems to evaluate the progression of JIA. Few pediatric-targeted radiographic scales are available for assessment of progression of JIA in growing joints, and the clinimetric and psychometric properties of such scales have been poorly investigated. We present a critique to the evaluative, discriminative, and predictive roles of the van der Heijde modification of Sharp's radiographic method, a scale originally designed to assess damage to joints of adults with rheumatoid arthritis, when it is applied to a pediatric population. We discuss the advantages and drawbacks of this radiographic scoring system for assessing growing joints and the ability of MRI to overcome inadequacies of conventional radiography. (orig.)

  14. A wireless-sensor scoring and training system for combative sports

    Science.gov (United States)

    Partridge, Kane; Hayes, Jason P.; James, Daniel A.; Hill, Craig; Gin, Gareth; Hahn, Allan

    2005-02-01

    Although historically among the most popular of sports, today, combative sports are often viewed as an expression of our savage past. Of primary concern are the long term effects of participating in these sports on the health of participants. The scoring of such sports has also been the subject of much debate, with a panel of judges making decisions about very quick events involving large sums of prize money. This paper describes an electronic system for use primarily in the sport of boxing, though it is suitable for martial arts such as karate and taekwondo. The technology is based on a previously described sensor platform and integrates a network of sensors on the athlete"s head, body and hands. Using a Bluetooth network, physical contacts are monitored in near real-time or post event on a remote computer to determine legal hits and hence derivative measures like scoring and final outcomes. It is hoped that this system can be applied to reduce the need for full contact contests as well as provide a more reliable method of determining the outcome of a bout. Other benefits presented here include the ability to analyse an athlete's performance post match or training session, such as assessing the efficacy of training drills and effects of fatigue.

  15. Intelligent query by humming system based on score level fusion of multiple classifiers

    Science.gov (United States)

    Pyo Nam, Gi; Thu Trang Luong, Thi; Ha Nam, Hyun; Ryoung Park, Kang; Park, Sung-Joo

    2011-12-01

    Recently, the necessity for content-based music retrieval that can return results even if a user does not know information such as the title or singer has increased. Query-by-humming (QBH) systems have been introduced to address this need, as they allow the user to simply hum snatches of the tune to find the right song. Even though there have been many studies on QBH, few have combined multiple classifiers based on various fusion methods. Here we propose a new QBH system based on the score level fusion of multiple classifiers. This research is novel in the following three respects: three local classifiers [quantized binary (QB) code-based linear scaling (LS), pitch-based dynamic time warping (DTW), and LS] are employed; local maximum and minimum point-based LS and pitch distribution feature-based LS are used as global classifiers; and the combination of local and global classifiers based on the score level fusion by the PRODUCT rule is used to achieve enhanced matching accuracy. Experimental results with the 2006 MIREX QBSH and 2009 MIR-QBSH corpus databases show that the performance of the proposed method is better than that of single classifier and other fusion methods.

  16. Intelligent query by humming system based on score level fusion of multiple classifiers

    Directory of Open Access Journals (Sweden)

    Park Sung-Joo

    2011-01-01

    Full Text Available Abstract Recently, the necessity for content-based music retrieval that can return results even if a user does not know information such as the title or singer has increased. Query-by-humming (QBH systems have been introduced to address this need, as they allow the user to simply hum snatches of the tune to find the right song. Even though there have been many studies on QBH, few have combined multiple classifiers based on various fusion methods. Here we propose a new QBH system based on the score level fusion of multiple classifiers. This research is novel in the following three respects: three local classifiers [quantized binary (QB code-based linear scaling (LS, pitch-based dynamic time warping (DTW, and LS] are employed; local maximum and minimum point-based LS and pitch distribution feature-based LS are used as global classifiers; and the combination of local and global classifiers based on the score level fusion by the PRODUCT rule is used to achieve enhanced matching accuracy. Experimental results with the 2006 MIREX QBSH and 2009 MIR-QBSH corpus databases show that the performance of the proposed method is better than that of single classifier and other fusion methods.

  17. Performance assessment of the SOFA, APACHE II scoring system, and SAPS II in intensive care unit organophosphate poisoned patients.

    Science.gov (United States)

    Kim, Yong Hwan; Yeo, Jung Hoon; Kang, Mun Ju; Lee, Jun Ho; Cho, Kwang Won; Hwang, SeongYoun; Hong, Chong Kun; Lee, Young Hwan; Kim, Yang Weon

    2013-12-01

    This study assessed the ability of the Sequential Organ Failure Assessment (SOFA) and Acute Physiology, Chronic Health Evaluation (APACHE) II scoring systems, as well as the Simplified Acute Physiology Score (SAPS) II method to predict group mortality in intensive care unit (ICU) patients who were poisoned with organophosphate. The medical records of 149 organophosphate poisoned patients admitted to the ICU from September 2006 to December 2012 were retrospectively examined. The SOFA, APACHE II, and SAPS II were calculated based on initial laboratory data in the Emergency Department, and during the first 24 hr of ICU admission. The probability of death was calculated for each patient based on the SOFA score, APACHE II score, and SAPS II equations. The ability to predict group mortality by the SOFA score, APACHE II score, and SAPS II method was assessed using two by two decision matrices and receiver operating characteristic (ROC) curve analysis. A total of 131 patients (mean age, 61 yr) were enrolled. The sensitivities, specificities, and accuracies were 86.2%, 82.4%, and 83.2% for the SOFA score, respectively; 65.5%, 68.6%, and 67.9% for the APACHE II scoring system, respectively; and 86.2%, 77.5%, and 79.4% for the SAPS II, respectively. The areas under the curve in the ROC curve analysis for the SOFA score, APACHE II scoring system, and SAPS II were 0.896, 0.716, and 0.852, respectively. In conclusion, the SOFA, APACHE II, and SAPS II have different capability to discriminate and estimate early in-hospital mortality of organophosphate poisoned patients. The SOFA score is more useful in predicting mortality, and easier and simpler than the APACHE II and SAPS II.

  18. Evaluation of POSSUM scoring system in the treatment of osteoporotic fracture of the hip in elder patients

    Institute of Scientific and Technical Information of China (English)

    WANG Tie-jun; ZHANG Bo-hao; GU Gui-shan

    2008-01-01

    To evaluate the applicability of the modified physiological and operative severity score for enumeration of mortality and morbidity(POSSUM)scoring system in predicting mortality in the patients undergoing hip joint arthroplasty.Methods:A total of 295 patients with hip fractures were analyzed using the modified POSSUM surgical scoring system. The mean ages of the patients were 66.59 years in the complicative group,62.28 years in noncomplicative group,77.89 years in the death group and 63.25 years in the living group,respectively. The comparisons between the observed and predicted morbidity,between the observed and predicted mortality were made within 30 days after operation.Results:The average physiological scores and operative severity scores was 18.96±4.83 and 13.47±2.01 in compticative group, while 15.65±3.66 and 11.74±2.26 in noncomplicative group(P<0.05).The average physiological scores and operative severity scores was 25.56±3.78 and 14.22±0.67 in death group,while 16.46±4.09 and 12.25 ±2.33 in living group (P<0.05).Though POSSUM scoring system over-predicted the overall risk of death,its estimate was very close in the high risk groups(>10%). There was perfect consistence between the observed and the predicted morbidity as calculated by published predictor equation for morbidity,and consistence for mortality in the high risk band.Conclusions:Modified POSSUM scoring system may be used to predict the morbidity in patients with hip fracture.Furthermore,POSSUM scoring system overpredicts the overall risk of death, but its estimate iS close to the actual data in the high risk band(>10%).

  19. Mortality Risk Prediction by Application of PRISM Scoring System in Pediatric Intensive Care Unit

    OpenAIRE

    Mahdi Mohammadi; Afshin Fayyazi; Mohsen Raeisi; Noor Mohammad Noori; Ali Khajeh; Ghasem Miri-Aliabad

    2013-01-01

    Objective: The Pediatric Risk of Mortality (PRISM) score is one of the scores used by many pediatricians for prediction of the mortality risk in the pediatric intensive care unit (PICU). Herein, evaluate the efficacy of PRISM score in prediction of mortality rate in PICU.Methods: In this cohort study, 221 children admitted during an 18-month period to PICU, were enrolled. PRISM score and mortality risk were calculated. Follow up was noted as death or discharge. Results were analyzed by Kaplan...

  20. Biological markers in Helicobacter pylori-associated gastritis and carcinoma: the value of a scoring system

    International Nuclear Information System (INIS)

    Helicobacter pylori-associated gastritis has been linked to the pathogenesis of gastric adenocarcinoma (GA), especially when assciated with intestinal metaplasia (IM) and atypia/dysplasia (A/D). We examined p53 expression, ploidy and proliferative activity and assessed H.pylori infection in relationship to IM and A/Din case of gastritis not associated with GA and in cases of GA. We examined 53 gastric biopsies from patients with gastritis not associated with GA, including patients with IM and/or A/D (n=35) and with gastritis associated with IM and/or A/D (n=21). Thirty-six distal gastrectomy specimens from patients with GA constituted a third group of patients. A scoring system that encompassed the presence or absence of H.Pylori, degree of gastritis, IM and/or A/D, p53, MIB-1prolefarative index (MPI) and ploidy was estimated in the cases of gastritis and in cancer associated mucosa (CAM) and the adenocarcinoma from patients withGA. Patients with GA had a higher median age than those with gastritis without IM and more were males (ratio 2.2:1). H.pylori was detected in 75% (40/53) of gastritis specimen and in 55% (20/36) of GA cases. There was a statistically significant difference between the incidence of gastritis without IM and/or A/D and CAM (p=0.01). p53 expression was seen in 67% of the cases (14/21) of gastritis with IM and/or A/D and only in 5% (2 cases ) of gastritis without IM (p=0.0005). A statistically significant difference in MPI was seen between CAM and GA (p=0.01) and gastritis without IM and/or A/D and gastritis with IM(p=0.004). Cases of gastritis without IM and/or or A/D has a median score of 8 while cases of gastritis with IM and/or A/D had a median score of 12 (p=0.0003). CAM had a median score of 13, which was significantly different than gastritis without IM and/or A/D(p=0.0003) The presence of IM and/or A/D can be used in H.pylori -associated gastritis as as starting point to further investigate high risk lesions. Those showing p53 expression

  1. A quantitative assessment of alkaptonuria: testing the reliability of two disease severity scoring systems.

    Science.gov (United States)

    Cox, Trevor F; Ranganath, Lakshminarayan

    2011-12-01

    Alkaptonuria (AKU) is due to excessive homogentisic acid accumulation in body fluids due to lack of enzyme homogentisate dioxygenase leading in turn to varied clinical manifestations mainly by a process of conversion of HGA to a polymeric melanin-like pigment known as ochronosis. A potential treatment, a drug called nitisinone, to decrease formation of HGA is available. However, successful demonstration of its efficacy in modifying the natural history of AKU requires an effective quantitative assessment tool. We have described two potential tools that could be used to quantitate disease burden in AKU. One tool describes scoring the clinical features that includes clinical assessments, investigations and questionnaires in 15 patients with AKU. The second tool describes a scoring system that only includes items obtained from questionnaires used in 44 people with AKU. Statistical analyses were carried out on the two patient datasets to assess the AKU tools; these included the calculation of Chronbach's alpha, multidimensional scaling and simple linear regression analysis. The conclusion was that there was good evidence that the tools could be adopted as AKU assessment tools, but perhaps with further refinement before being used in the practical setting of a clinical trial. PMID:21744089

  2. A modified risk assessment scoring system for post laser in situ keratomileusis ectasia in topographically normal patients

    Directory of Open Access Journals (Sweden)

    Mohammad Miraftab

    2014-01-01

    Conclusion: Our modified ectasia risk scoring system for patients with normal corneal topography can predict post LASIK ectasia risk with acceptable sensitivity and specificity. However, there are still unidentified risk factors for which further studies are required.

  3. Development of an automated updated selvester QRS scoring system using SWT-based QRS fractionation detection and classification

    OpenAIRE

    Bono, Valentina; Mazomenos, Evangelos B.; Chen, Taihai; Rosengarten, James; Acharyya, Amit; Maharatna, Koushik; Morgan, John M.; Curzen, Nick

    2014-01-01

    The Selvester score is an effective means for estimating the extent of myocardial scar in a patient from lowcost ECG recordings. Automation of such a system is deemed to help implementing low-cost high-volume screening mechanisms of scar in the primary care. This article describes, for the first time to the best of our knowledge, an automated implementation of the updated Selvester scoring system for that purpose, where fractionated QRS morphologies and patterns are identified and classified ...

  4. A scoring system for the assessment of angiographic findings in non-occlusive mesenteric ischemia (NOMI)

    Energy Technology Data Exchange (ETDEWEB)

    Minko, P.; Stroeder, J.; Miodek, J.; Buecker, A.; Katoh, M. [Saarland Univ. Hospital, Homburg/Saar (Germany). Diagnostic and Interventional Radiology; Groesdonk, H.; Schaefers, H.J. [Saarland Univ. Hospital, Homburg/Saar (Germany). Dept. of Thoracic and Cardiovascular Surgery; Graeber, S. [Saarland Univ. Hospital, Homburg/Saar (Germany). Inst. of Medical Biometry, Epidemiology and Medical Informatics

    2012-09-15

    Purpose: To establish a standardized scoring system for angiographic findings in patients with non-occlusive mesenteric ischemia (NOMI). Materials and Methods: In 36 patients (mean age: 72 years), 53 angiographies of the superior mesenteric artery (SMA) were performed for suspected NOMI after cardiac or major aortic surgery. All examinations were performed using a standardized DSA technique. Two experienced radiologists performed a consensus reading blinded to the clinical information, on two occasions with an interval of two weeks. In order to investigate the reproducibility of the criteria, the images were assessed once by an intensivist and a medical student. Image analysis was performed with respect to vessel morphology, reflux of contrast medium into the aorta, small bowel parenchymal contrast enhancement and distension and the delay between arterial injection and portal vein filling. Results: Almost perfect intra-observer correlation was obtained for the assessment of the contrast medium reflux ({kappa} = 0.82) and substantial correlation for the time of portal vein filling ({kappa} = 0.66). Moderate correlations were obtained for the vessel morphology ({kappa} = 0.51), small bowel enhancement ({kappa} = 0.63) and distension ({kappa} = 0.53). Contrast medium reflux into the aorta ({kappa} = 0.77 and 0.63) and the time of portal vein filling ({kappa} = 0.42 and 0.58) resulted in the highest inter-observer correlations between the radiologists and the intensivist as well as the radiologists and the student. Conclusion: In patients with suspected NOMI, using our scoring system yields high intra- and inter-observer correlations, allowing a standardized evaluation of angiographic findings. (orig.)

  5. Carpal erosions in children with juvenile idiopathic arthritis: repeatability of a newly devised MR-scoring system

    Energy Technology Data Exchange (ETDEWEB)

    Boavida, Peter [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); Lambot-Juhan, Karen [Hospital Necker Enfants Malades, Department of Radiology, Paris (France); Ording Mueller, Lil-Sofie [Oslo University Hospital, Department of Radiology, Oslo (Norway); Damasio, Beatrice; Malattia, Clara [Ospedale Pediatrico Gaslini, Department of Rheumatology, Genoa (Italy); Tanturri de Horatio, Laura [Ospedale Pediatrico Bambino Gesu, Department of Radiology, Rome (Italy); Owens, Catherine M. [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); UCL, Institute of Child Health, London (United Kingdom); Rosendahl, Karen [Haukeland University Hospital, Department of Radiology, Bergen (Norway); University of Bergen, Department of Clinical Medicine, Bergen (Norway)

    2015-12-15

    Juvenile idiopathic arthritis (JIA) is characterized by synovial inflammation, with potential risk of developing progressive joint destruction. Personalized state-of-the-art treatment depends on valid markers for disease activity to monitor response; however, no such markers exist. To evaluate the reliability of scoring of carpal bone erosions on MR in children with JIA using two semi-quantitative scoring systems. A total of 1,236 carpal bones (91 MR wrist examinations) were scored twice by two independent pediatric musculoskeletal radiologists. Bony erosions were scored according to estimated bone volume loss using a 0-4 scale and a 0-10 scale. An aggregate erosion score comprising the sum total carpal bone volume loss was calculated for each examination. The 0-4 scoring system resulted in good intra-reader agreement and moderate to good inter-observer agreement in the assessment of individual bones. Fair and moderate agreement were achieved for inter-reader and intra-reader agreement, respectively, using the 0-10 scale. Intra- and particularly inter-reader aggregate score variability were much less favorable, with wide limits of agreement. Further analysis of erosive disease patterns compared with normal subjects is required, and to facilitate the development of an alternative means of quantifying disease. (orig.)

  6. Carpal erosions in children with juvenile idiopathic arthritis: repeatability of a newly devised MR-scoring system

    International Nuclear Information System (INIS)

    Juvenile idiopathic arthritis (JIA) is characterized by synovial inflammation, with potential risk of developing progressive joint destruction. Personalized state-of-the-art treatment depends on valid markers for disease activity to monitor response; however, no such markers exist. To evaluate the reliability of scoring of carpal bone erosions on MR in children with JIA using two semi-quantitative scoring systems. A total of 1,236 carpal bones (91 MR wrist examinations) were scored twice by two independent pediatric musculoskeletal radiologists. Bony erosions were scored according to estimated bone volume loss using a 0-4 scale and a 0-10 scale. An aggregate erosion score comprising the sum total carpal bone volume loss was calculated for each examination. The 0-4 scoring system resulted in good intra-reader agreement and moderate to good inter-observer agreement in the assessment of individual bones. Fair and moderate agreement were achieved for inter-reader and intra-reader agreement, respectively, using the 0-10 scale. Intra- and particularly inter-reader aggregate score variability were much less favorable, with wide limits of agreement. Further analysis of erosive disease patterns compared with normal subjects is required, and to facilitate the development of an alternative means of quantifying disease. (orig.)

  7. Supraclavicular scalenectomy for thoracic outlet syndrome--functional outcomes assessed using the DASH scoring system.

    LENUS (Irish Health Repository)

    Glynn, Ronan W

    2012-02-01

    To evaluate supraclavicular scalenectomy ± cervical rib excision for thoracic outlet syndrome (TOS), employing Disability of Arm, Shoulder, and Hand (DASH) scoring for functional assessment post-decompression.

  8. Correlation of delta high-resolution computed tomography (HRCT) score with delta clinical variables in early systemic sclerosis (SSc) patients

    Science.gov (United States)

    Euathrongchit, Juntima; Wattanawittawas, Pittaporn; Kasitanon, Nuntana

    2016-01-01

    Background The correlation of changes (delta: Δ) of high-resolution computed tomography (HRCT) score with the Δ of other clinical variables has not been well studied. The purpose of this study was to determine the correlation of Δ HRCT score with Δ percent predicted forced vital capacity (%pFVC), Δ modified Rodnan Skin Score (mRSS), Δ erythrocyte sedimentation rate (ESR), and Δ percent of oxygen saturation at room air (%SpO2) in patients with early systemic sclerosis (SSc). Methods We used an inception cohort of early-SSc patients seen at the Rheumatology Clinic, Chiang Mai University, Thailand, between January 2010 and June 2014. All patients underwent HRCT at study entry and every 12 months thereafter. Thirty-one SSc patients who underwent pulmonary function test (PFT) within 12 weeks of their corresponding HRCT at baseline and last visit were identified. The extent of ground glass (GG), lung fibrosis (Fib), bronchiectasis (B), and honeycombing (HC) was scored, and then aggregated to produce a total (t) HRCT score. Results Mean ± SD age and disease duration from non-Raynaud’s phenomenon (NRP) to undergo HRCT at baseline were 52.2±8.8 years and 11.7±7.1 months, respectively. Seventeen (54.8%) patients were female and 20 (64.5%) were classified as dcSSc. The mean ± SD interval between the two HRCT tests was 16.0±7.2 months. The Δ HRCT scores [total fibrosis scores (t-Fib), total bronchiectasis scores (t-B), and total HRCT score (t-HRCT) scores] and Δ mRSS, but not Δ %pFVC, showed significant change over the observation period. We found significant correlation of Δ total honeycombing scores (t-HC) with Δ ESR (r=−0.44, P<0.05), and Δ t-Fib with Δ %SpO2 (r=−0.38, P<0.05). However, no significant correlation of any Δ HRCT scores with Δ %pFVC and Δ mRSS were observed. Conclusions In this study, the changes in the HRCT scores were greater than %pFVC; this, along with their correlations with the changes in ESR and %SpO2, suggest that HRCT

  9. New Combined Scoring System for Predicting Respiratory Failure in Iraqi Patients with Guillain-Barré Syndrome

    Directory of Open Access Journals (Sweden)

    Zaki Noah Hasan

    2010-09-01

    Full Text Available The Guillain-Barré syndrome (GBS is an acute post-infective autoimmune polyradiculoneuropathy, it is the commonest peripheral neuropathy causing respiratory failure. The aim of the study is to use the New Combined Scoring System in anticipating respiratory failure in order to perform elective measures without waiting for emergency situations to occur.
    Patients and methods: Fifty patients with GBS were studied. Eight clinical parameters (including progression of patients to maximum weakness, respiratory rate/minute, breath holding
    count (the number of digits the patient can count in holding his breath, presence of facial muscle weakness (unilateral or bilateral, presence of weakness of the bulbar muscle, weakness of the neck flexor muscle, and limbs weakness were assessed for each patient and a certain score was given to
    each parameter, a designed combined score being constructed by taking into consideration all the above mentioned clinical parameters. Results and discussion: Fifteen patients (30% that were enrolled in our study developed respiratory failure. There was a highly significant statistical association between the development of respiratory failure and the lower grades of (bulbar muscle weakness score, breath holding count scores, neck muscle weakness score, lower limbs and upper limbs weakness score , respiratory rate score and the total sum score above 16 out of 30 (p-value=0.000 . No significant statistical difference was found regarding the progression to maximum weakness (p-value=0.675 and facial muscle weakness (p-value=0.482.
    Conclusion: The patients who obtained a combined score (above 16’30 are at great risk of having respiratory failure.

  10. Landing Error Scoring System (LESS) Items are Associated with the Incidence Rate of Lower Extremity Stress Fracture

    OpenAIRE

    Cameron, Kenneth L.; Peck, Karen Y.; Owens, Brett D; Svoboda, Steven J.; DiStefano, Lindsay J.; Stephen W Marshall; de la Motte, Sarah; Beutler, Anthony I.; Padua, Darin A.

    2014-01-01

    Objectives: Lower-extremity stress fracture injuries are a major cause of morbidity in physically active populations. The ability to efficiently screen for modifiable risk factors associated with injury is critical in developing and implementing effective injury prevention programs. The purpose of this study was to determine if baseline Landing Error Scoring System (LESS) scores were associated with the incidence rate of lower-extremity stress fracture during four years of follow-up. Methods:...

  11. Kruis scoring system and Manning's criteria in diagnosis of irritable bowel syndrome: is it better to use combined?

    Science.gov (United States)

    Doğan, U B; Unal, S

    1996-01-01

    Irritable bowel syndrome (IBS) is characterized by abdominal pain and alteration of bowel habits. Manning et al. have reported that certain symptoms distinguished IBS from organic gastrointestinal disease (OGD); these were pain relieved by defecation, looser or more frequent stools at the onset of pain, abdominal distention, mucus, and a feeling of incomplete evacuation. Another simple scoring system for discriminating IBS from OGD that incorporated historical data, physical examination findings, and basic investigations was first devised by Kruis et al. In differential diagnosis of IBS from OGD, to evaluate the reliability of Manning's criteria and Kruis scoring system when used apart or combined; we studied 347 out-patients who completed a bowel disease questionnaire which objectively measured Manning's criteria and scoring system of Kruis. The group included 165 patients with IBS and 182 patients with OGD. The Manning's criteria discriminated IBS from OGD with a sensitivity of 90% and a specificity of 87% if three or more items were regarded as positive. Also the Kruis scoring system discriminated IBS from OGD with a sensitivity of 81% and a specificity of 91%. When used together, these systems discriminated IBS from OGD with a sensitivity of 80% and a specificity of 97%. Manning's criteria and Kruis scoring system had a strong correlation when compared in IBS, but not in OGD.

  12. Investigating the Generalizability of Scores from Different Rating Systems in Performance Assessment.

    Science.gov (United States)

    Kim, Sungsook C.

    The generalizability of scores from different scales in performance assessment was studied. First, a concept map of teachers' and raters' perceptions about various scores and scales was constructed using multidimensional scaling analysis. Then, a generalizability study using a random, partially nested design was conducted to analyze the…

  13. Modeling of Sediment Transport and Self-Cleansing in Sea Outfalls

    DEFF Research Database (Denmark)

    Larsen, Torben; Ibro, I.

    2011-01-01

    The paper describes an on-going project on modeling of sediment transport in outfalls with special focus on the self-cleansing problem occurring due to the daily flow variations seen in outfalls. The two central elements of the project is the development of the numerical model and a matching phys...

  14. Clinical and microbiologic effects of chemical versus mechanical cleansing in professional supportive implant therapy

    NARCIS (Netherlands)

    Strooker, H; Rohn, S; Van Winkelhoff, AJ

    1998-01-01

    The aim of the present study was to compare the cleansing properties of mechanical supportive care for dental implants with the use of an etching gel. Sixteen patients underwent a 5-month clinical trial with monthly recalls. These patients, wearing maxillary complete dentures and mandibular overdent

  15. Explanations for Child Sexual Abuse Given by Convicted Offenders in Malawi: No Evidence for "HIV Cleansing"

    Science.gov (United States)

    Mtibo, Charles; Kennedy, Neil; Umar, Eric

    2011-01-01

    Objective: A commonly cited, but unproven reason given for the rise in reported cases of child sexual abuse in Sub-Saharan Africa is the "HIV cleansing myth"--the belief that an HIV infected individual can be cured by having sex with a child virgin. The purpose of this study was to explore in Malawi the reasons given by convicted sex offenders for…

  16. Predictive value of semi-quantitative MRI-based scoring systems for future knee replacement: data from the osteoarthritis initiative

    Energy Technology Data Exchange (ETDEWEB)

    Hafezi-Nejad, Nima; Eng, John; Demehri, Shadpour [Johns Hopkins University School of Medicine, Musculoskeletal Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Baltimore, MD (United States); Zikria, Bashir [Johns Hopkins University, Department of Orthopedic Surgery, Baltimore, MD (United States); Carrino, John A. [Hospital for Special Surgery, Department of Radiology and Imaging, New York, NY (United States)

    2015-11-15

    To evaluate, in a confirmatory fashion, whether baseline and change from baseline to 24-month follow-up in cartilage damage, bone marrow lesions and meniscal damage are predictors of knee replacement (KR) in subjects with a high risk of osteoarthritis (OA), independent of the level of physical activity, symptom severity and radiographic abnormalities. Data from the Osteoarthritis Initiative's (OAI) baseline and 24-month follow-up knee MRIs of 115 patients (age range: 45-78 years; 48 % female; BMI: 20.9-48.7) were analyzed. Cartilage, bone marrow and menisci were semi-quantitatively scored according to the Whole-Organ Magnetic Resonance Imaging Score (WORMS) and Boston-Leeds Osteoarthritis Knee Score (BLOKS) systems in all compartments. Baseline and 24-month interval changes in structural tissue damage assessed by BLOKS and WORMS were used as predictors of KR independent of clinical and radiographic parameters using Cox hazard analysis. Adjustments were performed for age, gender, BMI and physical activity (Physical Activity Scale for the Elderly: PASE), Western Ontario and McMaster Questionnaire (WOMAC) total score and radiographic Kellgren-Lawrence (KL) score. BLOKS and WORMS baseline cartilage scores were predictors of KR independent of the PASE, WOMAC and KL score. One score increase in the average baseline BLOKS full-thickness cartilage defect score was associated with a [hazard ratio (95 % CI)] 13.55 (3.61-50.89) times greater risk of KR independent of the PASE, WOMAC and KL score. Net reclassification improvements (NRIs) of the additional evaluation of 24-month follow-up MRI scores and assessment of changes were not significant for prediction of KR (NRI range: - 7.23 - 24.8 %). The BLOKS cartilage score for full-thickness cartilage defects had the highest hazard for KR. Follow-up MRI changes in structural tissue damage, detected by BLOKS and WORMS cartilage, bone marrow or meniscus scores (up to 24 months) had no significant predictive value in addition

  17. An in vitro Evaluation on a Novel Root Canal Cleansing Method by Using Nylon Fibers

    Directory of Open Access Journals (Sweden)

    Shiqian Gao

    2015-07-01

    Full Text Available Despite traditional metal-based dental files, such as NiTi being demonstrated effective in root cleaning, the tooth structure is always damaged. Thus, to fulfill the need for a minimally invasive tool for contemporary endodontics and dentistry, the use of polymer fibers might provide a good option, as it is soft, fabricable, and disposable. In this study, two types of nylon fibers with respective average diameters of 206.9 µm (fiber W and 156.4 µm (fiber B, respectively, were used as dental files, and mounted onto either a reciprocating or a low-speed rotary hand-piece. In vitro, simulated root canal models were colored red using nail varnish, and then cleaned by the fiber files mounted on the hand-pieces. Three parts of the simulated models, i.e., the apical third, the medium third, and the coronal third, were chosen to assess the cleaning the efficiency (CE of each specimen by calculating the ratio of the cross-sectional area changes, before and after cleansing, using micro-Computer Tomography (CT. A NiTi file with a low-speed hand-piece was used as a control. SEM was used to observe the nylon fiber surfaces before and after the cleansing. Micro-CT results showed that for both the nylon fibers, W and B, an average CE of 82.11% ± 9.68% for the medium third could be achieved, which is statistically higher (p < 0.01 than the coronal third and apical third. The cleansing efficiency was not affected by, the types of fibers, nor the hand-pieces according to student’s t-test. Most of the nylon fibers could withstand deformation after the cleansing. To conclude, nylon fiber files have demonstrated a certain cleansing efficiency in simulated root canals, and micro-CT is a promising method to assess CE.

  18. Reliability and validity of a modified gait scoring system and its use in assessing tibial dyschondroplasia in broilers.

    Science.gov (United States)

    Garner, J P; Falcone, C; Wakenell, P; Martin, M; Mench, J A

    2002-07-01

    1. The gait scoring system for broilers developed by Kestin et al. (Veterinary Record, 131: 190-194, 1992) has been widely used to evaluate leg problems. The many factors and measures associated with this scale have empirically established its external (biological) validity. However, published test-retest (within-observer) reliabilities are poor, and inter-observer reliabilities are unknown. We evaluated several modifications to this scale aimed at improving its objectivity and reliability. 2. Eighteen naïve observers scored a standardised video of birds exhibiting varying degrees of lameness, either using Kestin et al.'s system, or our modified system. 3. Test-retest reliability (0.906) for Kestin et al.'s system was higher than previously reported. Inter-rater reliability was also good (0.892). The modified system offered significantly better test-retest (0.948) and inter-rater reliabilities (0.943), without incurring costs in terms of time taken or difficulty of use. The systems were consistent, assigning individual birds the same score on average. 4. It is concluded that the modified system offers the advantages of reduced error within and between studies. 5. In a second experiment, we used our modified scoring system to examine the relationship between tibial dyschondroplasia (TD) and gait score in 267 selected broilers. 6. Neither the presence nor severity of TD affected gait score, suggesting that, at least in this strain of broilers, other leg problems like slipped tendons or torsional deformities had more influence on gait impairment than did TD. PMID:12195794

  19. Comparison of a classical with a highly formularized body condition scoring system for dairy cattle

    OpenAIRE

    Isense, A.; Leiber, F.; Bieber, A.; Spengler, A.; Ivemeyer, S.; Maurer, V.; Klocke, Peter

    2014-01-01

    Body condition scoring is a common tool to assess the subcutaneous fat reserves of dairy cows. Because of its subjectivity, which causes limits in repeatability, it is often discussed controversially. Aim of the current study was to evaluate the impact of considering the cows overall appearance on the scoring process and on the validity of the results. Therefore, two different methods to reveal body condition scores (BCS), ‘independent BCS’ (iBCS) and ‘dependent BCS’ (dBCS), were used to asse...

  20. Distinct characteristics and new prognostic scoring system for Chinese patients with Waldenstr(o)m macroglobulinemia

    Institute of Scientific and Technical Information of China (English)

    Yi Shuhua; Cui Rui; Li Zengjun; An Gang; Qi Junyuan; Zou Dehui; Zhang Peihong

    2014-01-01

    Background Waldenstr(o)m macroglobulinemia (WM) is an uncommon lymphoid malignancy.The characteristics and prognosis of WM have never been systematically studied in the East.Methods We analyzed the clinical characteristics and the prognostic factors of 90 Chinese WM patients,and compared them with the Western reports.Results The median age was 62 years old with a male-to-female ratio of 3.74.The most common symptoms at diagnosis were fatigue (77.8%) and bleeding (20%),while only 6 patients (6.7%) were asymptomatic.In the univariate analysis,age >62 years,thrombocytopenia,leucopenia,cytopenias ≥2,and high risk on the international prognostic scoring system for WM were the adverse risk factors,but only age >62 years and ≥2 cytopenias were the independent prognostic factors in the multivariate analysis.Using age <62 years and ≥2 cytopenias,three significantly different prognostic groups could been distinguished,with 5-year overall survival of 71.6%,48.6%,and 17.0% (P <0.001).Conclusion Distinct characteristics exist in WM in China compared to the West and we describe a new simple prognostic model for newly diagnosed WM patients.

  1. AGRICULTURAL COOPERATIVE FIRMS: BUDGETARY ADJUSTMENTS AND ANALYSIS OF CREDIT ACCESS APPLYING SCORING SYSTEMS

    Directory of Open Access Journals (Sweden)

    Giuseppe Bonazzi

    2014-01-01

    Full Text Available Cooperatives are one of the most important types of companies in the agricultural sector. Cooperatives allow overcoming the limitations of the fragmentation of agricultural property, increasing the level of production of small-sized farms and selling the product so that it reaches a sufficient critical mass. Moreover, cooperatives are often characterized by undercapitalization and even difficult credit access because banks conduct their analysis applying rating systems that do not take into account the typicality of the cooperative budget. To assess this topic, in this article, an analysis has been conducted on a sample of 100 cooperatives, making adjustments to the annual budget in order to consider the typicality of their annual accounts. The results of the analysis show that suggested adjustments allow a more correct expression of the economic results and capital adequacy of the cooperative and that the results, expressed in terms of scoring, are higher than that achieved by a traditional analysis. This methodology could improve the credit access capacity for agricultural cooperatives and then reduce financial constraints, particularly in developing countries.

  2. A scoring system for bruise patterns: a tool for identifying abuse

    OpenAIRE

    Dunstan, F; Guildea, Z; Kontos, K; Kemp, A.; Sibert, J

    2002-01-01

    Aims: To determine whether abused and non-abused children differ in the extent and pattern of bruising, and whether any differences which exist are sufficiently great to develop a score to assist in the diagnosis of abuse.

  3. Evaluation of scoring system in cytological diagnosis and management of breast lesion with review of literature

    Directory of Open Access Journals (Sweden)

    N M Nandini

    2011-01-01

    Full Text Available Background: Fine needle aspiration cytology (FNAC breast is generally considered as a rapid, reliable, and safe diagnostic tool to distinguish non-neoplastic from neoplastic breast lesions. Masood′s Scoring Index has been proposed to help in sub-grouping of breast lesions so as to help in surgical management. Aims: To assess the accuracy of Modified Masood′s Scoring Index (MMSI in the diagnosis of benign and malignant breast lesions in patients with palpable breast lump, and review of literature. Settings and Design: A prospective study from a tertiary care center. Material and Methods: This prospective study included a total of 100 cases, both females and males, with palpable breast lump, in the age range of 10-80 years, over a period of 2 years from January 2007 to 2009, who underwent FNAC. They were cytologically grouped into five categories as suggested by Masood et al, and confirmed by histopathology. Results: Evaluation of Masood Scoring Index led to modification (Modified Masood Scoring Index; MMSI by shifting score 9 from Group I to Group II, thus increasing the diagnostic accuracy of the breast lesions. Conclusions: MMSI was found to be a useful, easily reproducible scoring method of breast lesions to improve diagnostic accuracy of nonproliferative breast disease and proliferative breast disease without atypia cases, as the prognosis and treatment of these cases varies.

  4. High resolution computed tomography of the chest in cystic fibrosis (CF): is simplification of scoring systems feasible?

    International Nuclear Information System (INIS)

    The purpose of this study was to simplify HRCT scoring systems (SS) for CF by selecting representative HRCT parameters. Forty-two consecutive patients with CF underwent baseline and follow-up chest HRCT. Three radiologists evaluated 84 HRCTs employing five SS. ''Simplified'' HRCT SS were formed by selection of parameters exhibiting statistically significant relations with FEV1. Pulmonary function tests (PFTs) and nutrition (IBW%) were recorded. Regression analysis, Pearson correlation and T-test were used for statistical analysis. Three HRCT parameters were selected for the formation of ''simplified'' HRCT SS (severity of bronchiectasis, bronchial wall thickening, atelectasis-consolidation) using regression analysis. There was excellent correlation between each ''simplified'' and corresponding complete score (0.892 < r < 0.0967, p < 0.0001) or the remaining four complete scores (0.786 < r < 0.961, p < 0.0001). Strong correlation was found among the five ''simplified'' scores (0.803 < r < 0.997, p < 0.0001). Comparing baseline complete and ''simplified'' scores with corresponding follow-up ones, significant worsening was observed (p < 0.0001). PFTs and IBW% did not change significantly. HRCT scores correlated moderately with FVC and FEV1, but there was no correlation with FEF25-75 and IBW%. ''Simplified'' HRCT SS are as reliable as the complete ones and detect progression of lung disease earlier than clinical parameters. They are easy to use and could be adopted in clinical practice. (orig.)

  5. The utility of the balance error scoring system for mild brain injury assessments in children and adolescents.

    Science.gov (United States)

    Quatman-Yates, Catherine; Hugentobler, Jason; Ammon, Robin; Mwase, Najima; Kurowski, Brad; Myer, Gregory D

    2014-09-01

    The Balance Error Scoring System (BESS) is widely recognized as an acceptable assessment of postural control for adult patients following a mild traumatic brain injury (mTBI) or concussion. However, the measurement properties of the BESS as a post-mTBI assessment test for younger patients are not well understood. The purpose of this study was to evaluate the utility of the BESS as a post-mTBI assessment test for children and adolescents aged 8 to 18 years through 2 investigations: (1) a retrospective medical records review of the relationship among age, BESS scores, and other common post-mTBI assessment tests; and (2) a prospective study comparing BESS scores for a cohort of children with a recent mTBI and BESS scores for a cohort of matched healthy peers. Age was found to be significantly correlated with several of the BESS measures and the total BESS score (P < 0.05). Significant differences were observed between the injured and healthy cohorts for 3 of the BESS measures and the total BESS score. However, the observed differences were not likely to be clinically meaningful. Cumulatively, evidence from the literature and the results of these studies indicate that the BESS may be limited for producing accurate assessments of younger athletes' post-mTBI postural control abilities. Future research recommendations include testing of modified versions of the BESS or other alternatives for post-mTBI postural control assessments with younger individuals. PMID:25295764

  6. Risk stratification in cardiovascular disease primary prevention - scoring systems, novel markers, and imaging techniques.

    LENUS (Irish Health Repository)

    Zannad, Faiez

    2012-04-01

    The aim of this paper is to review and discuss current methods of risk stratification for cardiovascular disease (CVD) prevention, emerging biomarkers, and imaging techniques, and their relative merits and limitations. This report is based on discussions that took place among experts in the area during a special CardioVascular Clinical Trialists workshop organized by the European Society of Cardiology Working Group on Cardiovascular Pharmacology and Drug Therapy in September 2009. Classical risk factors such as blood pressure and low-density lipoprotein cholesterol levels remain the cornerstone of risk estimation in primary prevention but their use as a guide to management is limited by several factors: (i) thresholds for drug treatment vary with the available evidence for cost-effectiveness and benefit-to-risk ratios; (ii) assessment may be imprecise; (iii) residual risk may remain, even with effective control of dyslipidemia and hypertension. Novel measures include C-reactive protein, lipoprotein-associated phospholipase A(2) , genetic markers, and markers of subclinical organ damage, for which there are varying levels of evidence. High-resolution ultrasound and magnetic resonance imaging to assess carotid atherosclerotic lesions have potential but require further validation, standardization, and proof of clinical usefulness in the general population. In conclusion, classical risk scoring systems are available and inexpensive but have a number of limitations. Novel risk markers and imaging techniques may have a place in drug development and clinical trial design. However, their additional value above and beyond classical risk factors has yet to be determined for risk-guided therapy in CVD prevention.

  7. An acoustic feature-based similarity scoring system for speech rehabilitation assistance.

    Science.gov (United States)

    Syauqy, Dahnial; Wu, Chao-Min; Setyawati, Onny

    2016-08-01

    The purpose of this study is to develop a tool to assist speech therapy and rehabilitation, which focused on automatic scoring based on the comparison of the patient's speech with another normal speech on several aspects including pitch, vowel, voiced-unvoiced segments, strident fricative and sound intensity. The pitch estimation employed the use of cepstrum-based algorithm for its robustness; the vowel classification used multilayer perceptron (MLP) to classify vowel from pitch and formants; and the strident fricative detection was based on the major peak spectral intensity, location and the pitch existence in the segment. In order to evaluate the performance of the system, this study analyzed eight patient's speech recordings (four males, four females; 4-58-years-old), which had been recorded in previous study in cooperation with Taipei Veterans General Hospital and Taoyuan General Hospital. The experiment result on pitch algorithm showed that the cepstrum method had 5.3% of gross pitch error from a total of 2086 frames. On the vowel classification algorithm, MLP method provided 93% accuracy (men), 87% (women) and 84% (children). In total, the overall results showed that 156 tool's grading results (81%) were consistent compared to 192 audio and visual observations done by four experienced respondents. Implication for Rehabilitation Difficulties in communication may limit the ability of a person to transfer and exchange information. The fact that speech is one of the primary means of communication has encouraged the needs of speech diagnosis and rehabilitation. The advances of technology in computer-assisted speech therapy (CAST) improve the quality, time efficiency of the diagnosis and treatment of the disorders. The present study attempted to develop tool to assist speech therapy and rehabilitation, which provided simple interface to let the assessment be done even by the patient himself without the need of particular knowledge of speech processing while at the

  8. Comparison of severity of illness scoring systems for patients with nosocomial bloodstream infection due to Pseudomonas aeruginosa

    Directory of Open Access Journals (Sweden)

    Wenzel Richard P

    2006-08-01

    Full Text Available Abstract Background Several acute illness severity scores have been proposed for evaluating patients on admission to intensive care units but these have not been compared for patients with nosocomial bloodstream infection (nBSI. We compared three severity of illness scoring systems for predicting mortality in patients with nBSI due to Pseudomonas aeruginosa. Methods We performed a historical cohort study on 63 adults in intensive care units with P. aeruginosa monomicrobial nBSI. Results The Acute Physiology, Age, Chronic Health Evaluation II (APACHE II, Sequential Organ Failure Assessment (SOFA, and Simplified Acute Physiologic Score (SAPS II, were calculated daily from 2 days prior through 2 days after the first positive blood culture. Calculation of the area under the receiver operating characteristic (ROC curve confirmed that APACHE II and SAPS II at day -1 and SOFA at day +1 were better predictors of outcome than days -2, 0 and day 2 of BSI. By stepwise logistic regression analysis of these three scoring systems, SAPS II (OR: 13.03, CI95% 2.51–70.49 and APACHE II (OR: 12.51, CI95% 3.12–50.09 on day -1 were the best predictors for mortality. Conclusion SAPS II and APACHE II are more accurate than the SOFA score for predicting mortality in this group of patients at day -1 of BSI.

  9. Identification of the optimal donor quality scoring system and measure of early renal function in kidney transplantation.

    LENUS (Irish Health Repository)

    Moore, Jason

    2009-02-27

    The early identification of kidney allografts at risk of later dysfunction has implications for clinical practice. Donor quality scoring systems (preoperative) and measures of early allograft function (first week postoperative) have previously shown practical utility. This study aimed to determine the optimal parameter(s) (preoperative and postoperative) with greatest predictive power for the development of subsequent allograft dysfunction.

  10. Moderate precision of prognostic scoring systems in a consecutive, prospective cohort of 544 patients with metastatic spinal cord compression

    DEFF Research Database (Denmark)

    Morgen, Søren Schmidt; Nielsen, Dennis Hallager; Larsen, Claus Falck;

    2014-01-01

    and compared to the observed survival. We assessed how precise the scoring systems predicted survival with McNemar's test. The prognostic value was illustrated with Kaplan-Meier curves, and the individual prognostic components were analyzed with Cox regression analysis. RESULTS: The mean age was 65 years...

  11. Development of a questionnaire weighted scoring system to target diagnostic examinations for asthma in adults: a modelling study

    Directory of Open Access Journals (Sweden)

    Hazell Michelle L

    2004-12-01

    Full Text Available Abstract Background Identification and treatment of unrecognised asthmatics in the community is important for improving the health of the individual and minimising cost and quality of life burden. It is not practical to offer clinical diagnostic assessment to whole communities, and a simple tool such as a questionnaire is required to identify a smaller target group. Conventional questionnaire screening methods which separate individuals into positive and negative categories have resulted in large numbers of individuals requiring clinical assessment. This study has therefore developed and tested a weighted scoring system that prioritises those most urgently in need, based on their questionnaire responses. Methods A stratified random sample of adult respondents to a general practice postal questionnaire survey were categorised 'asthmatic' or 'non-asthmatic' according to three expert physicians' opinions. Based on this categorisation, logistic regression was used to derive weights reflecting the relative importance of each question in predicting asthma, allowing calculation of weighted scores reflecting likelihood of asthma. Respondents scoring higher than a chosen threshold would be offered diagnostic examination. Results Age and presence of wheeze were most influential (weight 3 and overall weighted scores ranged from -1 to 13. Positive predictive values (PPV were estimated. For example, setting the threshold score at nine gave an estimated PPV for asthma diagnosis of 93.5%, a threshold score of seven corresponded to PPV 78.8%. PPV estimates were supported by examining 145 individuals from a new survey. Conclusion Weighted scoring of questionnaire responses provides a method for evaluating the priority level of an individual 'at a glance', minimising the resource wastage of examining false positives.

  12. 78 FR 76160 - Public Housing Assessment System (PHAS) Capital Fund Interim Scoring Notice: Reinstitution of...

    Science.gov (United States)

    2013-12-16

    ... by an interim rule published on February 23, 2011, at 76 FR 10136. The Capital Fund Program Indicator... Scoring Notice, also published on February 23, 2011, at 76 FR 10053. Under this indicator, PHAs can... occupancy ] rate is accounted for under another indicator, the management operations indicator, at 24...

  13. An Inmate Classification System Based on PCL: SV Factor Scores in a Sample of Prison Inmates

    Science.gov (United States)

    Wogan, Michael; Mackenzie, Marci

    2007-01-01

    Psychopaths represent a significant management challenge in a prison population. A sample of ninety-five male inmates from three medium security prisons was tested using the Hare Psychopathy Checklist: Screening Version (PCL:SV). Using traditional criteria, 22% of the inmates were classified as psychopaths. Scores on the two factor dimensions of…

  14. Update on risk scoring systems for patients with upper gastrointestinal haemorrhage

    Institute of Scientific and Technical Information of China (English)

    Adrian J Stanley

    2012-01-01

    Upper gastrointestinal haemorrhage (UGIH) remains a common medical emergency worldwide.It is increasingly recognised that early risk assessment is an important part of management,which helps direct appropriate patient care and the timing of endoscopy.Several risk scores have been developed,most of which include endoscopic findings,although a minority do not.These scores were developed to identify various end-points including mortality,rebleeding or clinical intervention in the form of transfusion,endoscopic therapy or surgery.Recent studies have reported accurate identification of a very low risk group on presentation,using scores which require simple clinical or laboratory parameters only.This group may not require admission,but could be managed with early out-patient endoscopy.This article aims to describe the existing pre- and post-en-doscopy risk scores for UGIH and assess the published data comparing them in the prediction of outcome.Recent data assessing their use in clinical practice,in particular the early identification of low-risk patients,are also discussed.

  15. Managing What We Can Measure: Quantifying the Susceptibility of Automated Scoring Systems to Gaming Behavior

    Science.gov (United States)

    Higgins, Derrick; Heilman, Michael

    2014-01-01

    As methods for automated scoring of constructed-response items become more widely adopted in state assessments, and are used in more consequential operational configurations, it is critical that their susceptibility to gaming behavior be investigated and managed. This article provides a review of research relevant to how construct-irrelevant…

  16. 77 FR 47707 - Public Housing Assessment System (PHAS): Physical Condition Scoring Notice and Revised Dictionary...

    Science.gov (United States)

    2012-08-09

    ... Comment On October 13, 2011 (76 FR 63640), HUD published for public comment a notice revising the scoring... cap are described in the October 13, 2011, notice; see 76 FR 63641. In addition to the point loss cap... specific changes proposed are found at 76 FR 63648-63654 (October 13, 2011). II. This Final Notice...

  17. Antibacterial efficacy of Salvadora persica as a cleansing teeth towards Streptococcus mutans and Lactobacilli colonies

    Directory of Open Access Journals (Sweden)

    Erlina Sih Mahanani

    2012-12-01

    Full Text Available Background: Salvadora persica is a traditional chewing stick for cleaning teeth that it is known Siwak. Several studies have demonstrated the antimicrobial effects of Salvadora persica. Purpose: This study was aimed to examine the effectiveness of Salvadora persica in several modified preparation against the salivary Streptoccocus mutans and Lactobacilli. Methods: A single-blind, randomized clinical trial study with crossover design was used. The study comprised of 5 groups, per group consisted of 14 healthy dental students who had good oral hygiene. Each participant was given 5 intervention to clean their teeth using, electric toothbrush modified with siwak, electric toothbrush with siwak toothpaste (colgate kayu sugi toothpaste, electric toothbrush with general toothpaste (colgate total toothpaste, original siwak chewing stick and normal saline. The wash out periode each intervention was 3 days. Patients’ saliva was used to quantify the levels of Streptococcus mutans and Lactobacilli using caries risk test (CRT kit from Vivadent. Results: The results showed that there was a reduction in Streptococcus mutans and Lactobacilli risk score after cleansing different intervention except electric toothbrush modified with siwak. However, there was no significant difference for Streptococcus mutans (p=0.158 and Lactobacilli (p=0.396 risk score reduction when comparison was done between the groups. Conclusion: The original siwak chewing stick has antimicrobial effects similar to toothbrushing with general toothpaste and salvadora persica toothpaste. However, electric toothbrush modified with siwak has no effect on microbial reduction.Latar belakang: Salvadora persica adalah pembersih gigi tradisional yang lebih dikenal dengan sebutan Siwak. Beberapa penelitian menunjukkan bahwa Salvadora persica memiliki daya antibakteri. Tujuan: Penelitian ini bertujuan untuk mengetahui efektivitas Salvadora persica dalam berbagai bentuk sediaan untuk membersihkan

  18. Hyper-hydration: a new perspective on wound cleansing, debridement and healing.

    Science.gov (United States)

    2016-06-01

    In a recent symposium organised by Hartmann, the involvement of moisture and hydration in healing was re-evaluated and the use of hyper-hydration in promoting healing was examined. The distinction between hyperhydration and maceration was also discussed. Clinical studies were presented to give an overview of the clinical evidence to how Hydro-Responsive Wound Dressings can aid in healing via cleansing, debridement and desloughing of several wound types. PMID:27297574

  19. EFFICACY OF BIOFILM DISCLOSING AGENT AND OF THREE BRUSHES IN THE CONTROL OF COMPLETE DENTURE CLEANSING

    OpenAIRE

    Cláudia Helena Lovato da Silva; Helena de Freitas Oliveira Paranhos

    2006-01-01

    OBJECTIVE: This report evaluated the efficacy of three brushes and one biofilm disclosing agent in complete denture cleansing. METHODS: Twenty-seven wearers of maxillary dentures were distributed into three groups and received different brushes: Oral B40, conventional toothbrush (Oral B); Denture, denture-specific brush (Condor); Johnson & Johnson, denture-specific brush (Johnson & Johnson). The 60-day experimental period was divided into two techniques: I - brushing (brush associated with a ...

  20. Reproducibility of the NEPTUNE descriptor-based scoring system on whole-slide images and histologic and ultrastructural digital images.

    Science.gov (United States)

    Barisoni, Laura; Troost, Jonathan P; Nast, Cynthia; Bagnasco, Serena; Avila-Casado, Carmen; Hodgin, Jeffrey; Palmer, Matthew; Rosenberg, Avi; Gasim, Adil; Liensziewski, Chrysta; Merlino, Lino; Chien, Hui-Ping; Chang, Anthony; Meehan, Shane M; Gaut, Joseph; Song, Peter; Holzman, Lawrence; Gibson, Debbie; Kretzler, Matthias; Gillespie, Brenda W; Hewitt, Stephen M

    2016-07-01

    The multicenter Nephrotic Syndrome Study Network (NEPTUNE) digital pathology scoring system employs a novel and comprehensive methodology to document pathologic features from whole-slide images, immunofluorescence and ultrastructural digital images. To estimate inter- and intra-reader concordance of this descriptor-based approach, data from 12 pathologists (eight NEPTUNE and four non-NEPTUNE) with experience from training to 30 years were collected. A descriptor reference manual was generated and a webinar-based protocol for consensus/cross-training implemented. Intra-reader concordance for 51 glomerular descriptors was evaluated on jpeg images by seven NEPTUNE pathologists scoring 131 glomeruli three times (Tests I, II, and III), each test following a consensus webinar review. Inter-reader concordance of glomerular descriptors was evaluated in 315 glomeruli by all pathologists; interstitial fibrosis and tubular atrophy (244 cases, whole-slide images) and four ultrastructural podocyte descriptors (178 cases, jpeg images) were evaluated once by six and five pathologists, respectively. Cohen's kappa for inter-reader concordance for 48/51 glomerular descriptors with sufficient observations was moderate (0.40transformation. NEPTUNE digital pathology scoring system enables novel morphologic profiling of renal structures. For all histologic and ultrastructural descriptors tested with sufficient observations, moderate-to-excellent concordance was seen for 31/54 (57%). Descriptors not sufficiently represented will require further testing. This study proffers the NEPTUNE digital pathology scoring system as a model for standardization of renal biopsy interpretation extendable outside the NEPTUNE consortium, enabling international collaborations. PMID:27102348

  1. Reproducibility of the NEPTUNE descriptor-based scoring system on whole-slide images and histologic and ultrastructural digital images.

    Science.gov (United States)

    Barisoni, Laura; Troost, Jonathan P; Nast, Cynthia; Bagnasco, Serena; Avila-Casado, Carmen; Hodgin, Jeffrey; Palmer, Matthew; Rosenberg, Avi; Gasim, Adil; Liensziewski, Chrysta; Merlino, Lino; Chien, Hui-Ping; Chang, Anthony; Meehan, Shane M; Gaut, Joseph; Song, Peter; Holzman, Lawrence; Gibson, Debbie; Kretzler, Matthias; Gillespie, Brenda W; Hewitt, Stephen M

    2016-07-01

    The multicenter Nephrotic Syndrome Study Network (NEPTUNE) digital pathology scoring system employs a novel and comprehensive methodology to document pathologic features from whole-slide images, immunofluorescence and ultrastructural digital images. To estimate inter- and intra-reader concordance of this descriptor-based approach, data from 12 pathologists (eight NEPTUNE and four non-NEPTUNE) with experience from training to 30 years were collected. A descriptor reference manual was generated and a webinar-based protocol for consensus/cross-training implemented. Intra-reader concordance for 51 glomerular descriptors was evaluated on jpeg images by seven NEPTUNE pathologists scoring 131 glomeruli three times (Tests I, II, and III), each test following a consensus webinar review. Inter-reader concordance of glomerular descriptors was evaluated in 315 glomeruli by all pathologists; interstitial fibrosis and tubular atrophy (244 cases, whole-slide images) and four ultrastructural podocyte descriptors (178 cases, jpeg images) were evaluated once by six and five pathologists, respectively. Cohen's kappa for inter-reader concordance for 48/51 glomerular descriptors with sufficient observations was moderate (0.40transformation. NEPTUNE digital pathology scoring system enables novel morphologic profiling of renal structures. For all histologic and ultrastructural descriptors tested with sufficient observations, moderate-to-excellent concordance was seen for 31/54 (57%). Descriptors not sufficiently represented will require further testing. This study proffers the NEPTUNE digital pathology scoring system as a model for standardization of renal biopsy interpretation extendable outside the NEPTUNE consortium, enabling international collaborations.

  2. Anticandidal efficacy of denture cleansing tablet, Triphala, Aloe vera, and Cashew leaf on complete dentures of institutionalized elderly

    OpenAIRE

    Shetty, Pooja J.; Vijaya Hegde; Leslie Gomes

    2014-01-01

    With an increase in the number of dependent elderly, there is a need to introduce few natural products for denture cleansing, which are easily and economically available. Hence the aim of this study was to compare the anticandidal efficacy of denture cleansing tablet (sodium bicarbonate and sodium perborate monohydrate), Triphala (Phyllanthus emblica, Terminalia chebula and Terminalia belerica fruits powders in equal proportion), cashew leaf, Aloe vera and water (control) on complete dentures...

  3. Bowel cleansing before colonoscopy: Balancing efficacy,safety, cost and patient tolerance

    Institute of Scientific and Technical Information of China (English)

    2016-01-01

    Effective colorectal cancer screening relies on reliablecolonoscopy findings which are themselves dependenton adequate bowel cleansing. Research has consistentlydemonstrated that inadequate bowel preparationadversely affects the adenoma detection rate and leadsgastroenterologists to recommend earlier follow up thanis consistent with published guidelines. Poor preparationaffects as many as 30% of colonoscopies and contributesto an increased cost of colonoscopies. Patient tolerability isstrongly affected by the preparation chosen and mannerin which it is administered. Poor tolerability is, in turn,associated with lower quality bowel preparations. Recently,several new developments in both agents being usedfor bowel preparation and in the timing of administrationhave brought endoscopists closer to achieving the goal ofeffective, reliable, safe, and tolerable regimens. Historically,large volume preparations given in a single dose wereadministered to patients in order to achieve adequatebowel cleansing. These were poorly tolerated, and theunpleasant taste of and significant side effects producedby these large volume regimens contributed significantlyto patients' inability to reliably complete the preparationand to a reluctance to repeat the procedure. Smallervolumes, including preparations that are administered astablets to be consumed with water, given as split doseshave significantly improved both the patient experienceand efficacy, and an appreciation of the importance ofthe preparation to colonoscopy interval have producedadditional cleansing.

  4. Cleansing the colon in gallium-67 scintigraphy: a prospective comparison of regimens

    International Nuclear Information System (INIS)

    Colonic accumulation of gallium-67 frequently complicates the interpretation of gallium-67 scintigrams. Although various modes of cleansing the colon prior to scintigraphy have been suggested, there is controversy over their efficacy and none have been tested prospectively. Three hundred nine patients undergoing gallium-67 scintigraphy were randomly assigned to one of four cleansing regimens: (1) a high fiber diet (78 patients); (2) castor oil (76); (3) milk of magnesia and cascara (76); and (4) not preparation (79). Patient compliance rates for the four regimens were 17%, 32%, 36%, and 46%, respectively. After noncompliant patients were excluded, gallium-67 scintigrams were graded for colonic activity on a scale of 0-3 by three independent, experienced observers. Gallium-67 activity in the colon was significantly less after administration of castor oil than after no preparation (p . 0.047). A high fiber diet also resulted in a substantial reduction of colonic activity when compared with no preparation; the difference, however, was not statistically significant (p . 0.083). Regimen 3 did not produce significantly better results than regimen 4 (p . 0.42). A major impediment to the success of any cleansing regimen seems to be poor compliance of patients

  5. Validation of the Rockall scoring system for outcomes from non-variceal upper gastrointestinal bleeding in a Canadian setting

    Institute of Scientific and Technical Information of China (English)

    Robert A Enns; Yves M Gagnon; Alan N Barkun; David Armstrong; Jamie C Gregor; Richard N Fedorak

    2006-01-01

    AIM: To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death.METHODS: We used data extracted from the Registry of Upper Gastrointestinal Bleeding and Endoscopy including information of 1869 patients with non-variceal upper gastrointestinal bleeding treated in Canadian hospitals.Risk scores were calculated and used to classify patients based on outcomes. For each outcome, we used x2 goodness-of-fit tests to assess the degree of calibration,and built receiver operating characteristic curves and calculated the area under the curve (AUC) to evaluate the discriminative ability of the scoring system.RESULTS: For rebleeding, the x2 goodness-of-fit test indicated an acceptable fit for the model [x2 (8) = 12.83,P = 0.12]. For surgical procedures [x2 (8) = 5.3, P = 0.73]and death [x2 (8) = 3.78, P = 0.88], the tests showed solid correspondence between observed proportions and predicted probabilities. The AUC was 0.59 (95% CI:0.55-0.62) for the outcome of rebleeding and 0.60 (95% CI: 0.54-0.67) for surgical procedures, representing a poor discriminative ability of the scoring system. For the outcome of death, the AUC was 0.73 (95% CI: 0.69-0.78),indicating an acceptable discriminative ability.CONCLUSION: The Rockall scoring system provides an acceptable tool to predict death, but performs poorly for endpoints of rebleeding and surgical procedures.

  6. Myeloproliferative neoplasm (MPN) symptom assessment form total symptom score: Prospective international assessment of an abbreviated symptom burden scoring system among patients with MPNs

    NARCIS (Netherlands)

    R.M. Emanuel (Robyn); A.C. Dueck (Amylou); H.L. Geyer (Holly); J.J. Kiladjian; S. Slot (Stefanie); S. Zweegman (Sonja); P.A.W. Boekhorst; S. Commandeur (Suzan); H. Schouten (Harry); F. Sackmann (Federico); A.K. Fuentes (Ana Kerguelen); D. Hernández-Maraver (Dolores); C. Pahl (Clemens); M. Griesshammer (Martin); F. Stegelmann (Frank); K. Doehner (Konstanze); T. Lehmann (Thomas); K. Bonatz (Karin); A. Reiter (Alfred); F. Boyer (Francoise); J. Etienne (Jerome); J.-C. Ianotto (Jean-Christophe); D. Ranta (Dana); L. Roy (Lydia); J.-Y. Cahn (Jean-Yves); C.N. Harrison (Claire); D. Radia (Deepti); P. Muxi (Pablo); N. Maldonado (Norman); C. Besses (Carlos); F. Cervantes (Francisco); P.L. Johansson (Peter); T. Barbui (Tiziano); G. Barosi (Giovanni); A.M. Vannucchi (Alessandro); F. Passamonti (Francesco); B. Andreasson (Bjorn); M.L. Ferarri (Maria); A. Rambaldi (Alessandro); J. Samuelsson (Jan); G. Birgegard (Gunnar); A. Tefferi (Ayalew); A.A. Mesa

    2012-01-01

    textabstractPurpose: Myeloproliferative neoplasm (MPN) symptoms are troublesome to patients, and alleviation of this burden represents a paramount treatment objective in the development of MPN-directed therapies. We aimed to assess the utility of an abbreviated symptom score for the most pertinent a

  7. Validation of a New Pediatric Joint Scoring System From the International Hemophilia Prophylaxis Study Group: Validity of the Hemophilia Joint Health Score

    NARCIS (Netherlands)

    Feldman , M. Brian; Funk, M. Sharon; Bergstrom, Britt-Marie; Zourikian, Nichan; Hillard, Pamela; Net, van der Janjaap; Engelbert , H.H. Raoul; Petrini, Pia; Berg, Marijke van den H.; Manco-Johnson, J. Marilyn; Rivard, E. Georges; Abad, Audrey; Blanchette , S. Victor

    2011-01-01

    Objective. Repeated hemarthrosis in hemophilia causes arthropathy with pain and dysfunction. The Hemophilia Joint Health Score (HJHS) was developed to be more sensitive for detecting arthropathy than the World Federation of Hemophilia (WFH) physical examination scale, especially for children and tho

  8. Inter- and intra-observer variability associated with the use of the Mirels' scoring system for metastatic bone lesions.

    LENUS (Irish Health Repository)

    Mac Niocaill, Ruairi F

    2011-01-01

    Metastatic bone disease is increasing in association with ever-improving medical management of osteophylic malignant conditions. The precise timing of surgical intervention for secondary lesions in long bones can be difficult to determine. This paper aims to evaluate a classic scoring system. All radiographs were examined twice by three orthopaedic oncologists and scored according to the Mirels\\' scoring system. The Kappa statistic was used for the purpose of statistical analysis. The results show agreement between observers (κ = 0.35-0.61) for overall scores at the two time intervals. Inter-observer agreement was also seen with subset analysis of size (κ = 0.27-0.60), site (κ = 0.77-1.0) and nature of the lesion (κ = 0.55-0.81). Similarly, low levels of intra-observer variability were noted for each of the three surgeons (κ= 0.34, 0.39, and 0.78, respectively). These results indicate a reliable, repeatable assessment of bony metastases. We continue to advocate its use in the management of patients with long bone metastases.

  9. Evaluation of the neural function of nonhuman primates with spinal cord injury using an evoked potential-based scoring system

    Science.gov (United States)

    Ye, Jichao; Ma, Mengjun; Xie, Zhongyu; Wang, Peng; Tang, Yong; Huang, Lin; Chen, Keng; Gao, Liangbin; Wu, Yanfeng; Shen, Huiyong; Zeng, Yuanshan

    2016-01-01

    Nonhuman primate models of spinal cord injury (SCI) have been widely used in evaluation of the efficacy and safety of experimental restorative interventions before clinical trials. However, no objective methods are currently available for the evaluation of neural function in nonhuman primates. In our long-term clinical practice, we have used evoked potential (EP) for neural function surveillance during operation and accumulated extensive experience. In the present study, a nonhuman primate model of SCI was established in 6 adult cynomologus monkeys through spinal cord contusion injury at T8–T9. The neural function before SCI and within 6 months after SCI was evaluated based on EP recording. A scoring system including somatosensory evoked potentials (SSEPs) and transcranial electrical stimulation-motor evoked potentials (TES-MEPs) was established for the evaluation of neural function of nonhuman primates with SCI. We compared the motor function scores of nonhuman primates before and after SCI. Our results showed that the EP below the injury level significantly changed during the 6 months after SCI. In addition, a positive correlation was identified between the EP scores and motor function. The EP-based scoring system is a reliable approach for evaluating the motor function changes in nonhuman primates with SCI. PMID:27629352

  10. QT dispersion and prognostication of the outcome in acute cardiotoxicities: A comparison with SAPS II and APACHE II scoring systems.

    Science.gov (United States)

    Hassanian-Moghaddam, Hossein; Amiri, Hassan; Zamani, Nasim; Rahimi, Mitra; Shadnia, Shahin; Taherkhani, Maryam

    2014-06-01

    We aimed to evaluate the efficacy of QT dispersion (QTD) in determining the outcome of the patients poisoned by cardiotoxic medications and toxins. Patients who referred to our emergency department (ED) due to acute toxicity with any cardiotoxic medication or toxin and were admitted to medical toxicology intensive care unit (MTICU) were enrolled into the study. A questionnaire containing the demographic characteristics, vital signs, laboratory tests, electrocardiographic (ECG) parameters of the first ECG taken on MTICU or ED admission, simplified acute physiology score (SAPS), and acute physiology and chronic health evaluation (APACHE) score was filled for every single patient. QTD was manually calculated. The patients were divided into two groups of survivors and non-survivors and compared. Although QTD was not significantly different between the survivors and non-survivors (P = 0.8), SAPS II and APACHE II score were so. SAPS and APACHE had the highest sensitivity and specificity in determining the patients' mortality, respectively. SAPS had the highest sensitivity, and QTD had the highest specificity in predicting the later development of the complications. SAPS II and APACHE II scoring systems are the best systems for prognostication of death in patients with acute cardiotoxic medication-induced poisonings. QTD can be successfully used for the prediction of complications.

  11. Comparison of Hay's Criteria with Nugent's Scoring System for Diagnosis of Bacterial Vaginosis

    OpenAIRE

    Rohit Chawla; Preena Bhalla; Sanjim Chadha; Sujatha Grover; Suneela Garg

    2013-01-01

    Although Nugent’s criterion is considered as the gold standard for the diagnosis of bacterial vaginosis (BV), the method requires an experienced slide reader and considerable time and skill. In this study, we compared the method of Hay and Ison with Nugent’s scoring criteria. Vaginal specimens were collected from a total of 213 women, presenting with or without the symptoms of vaginitis. Diagnosis of BV was done using Nugent’ and Hay’s method. Sensitivity, specificity, and predictive values f...

  12. Analysis of Surgical Site Infection after Musculoskeletal Tumor Surgery: Risk Assessment Using a New Scoring System

    Directory of Open Access Journals (Sweden)

    Satoshi Nagano

    2014-01-01

    Full Text Available Surgical site infection (SSI has not been extensively studied in musculoskeletal tumors (MST owing to the rarity of the disease. We analyzed incidence and risk factors of SSI in MST. SSI incidence was evaluated in consecutive 457 MST cases (benign, 310 cases and malignant, 147 cases treated at our institution. A detailed analysis of the clinical background of the patients, pre- and postoperative hematological data, and other factors that might be associated with SSI incidence was performed for malignant MST cases. SSI occurred in 0.32% and 12.2% of benign and malignant MST cases, respectively. The duration of the surgery (P=0.0002 and intraoperative blood loss (P=0.0005 was significantly more in the SSI group than in the non-SSI group. We established the musculoskeletal oncological surgery invasiveness (MOSI index by combining 4 risk factors (blood loss, operation duration, preoperative chemotherapy, and the use of artificial materials. The MOSI index (0–4 points score significantly correlated with the risk of SSI, as demonstrated by an SSI incidence of 38.5% in the group with a high score (3-4 points. The MOSI index score and laboratory data at 1 week after surgery could facilitate risk evaluation and prompt diagnosis of SSI.

  13. Evaluation of clinical features scoring system as screening tool for influenza A (H1N1 in epidemic situations

    Directory of Open Access Journals (Sweden)

    P Ranjan

    2012-01-01

    Full Text Available Background: Influenza A (H1N1 hit the headlines in recent times and created mass hysteria and general panic. The high cost and non-availability of diagnostic laboratory tests for swine flu, especially in the developing countries underlines the need of having a cheaper, easily available, yet reasonably accurate screening test. Aims: This study was carried out to develop a clinical feature-based scoring system (CFSS for influenza A (H1N1 and to evaluate its suitability as a screening tool when large numbers of influenza-like illness cases are suspect. Settings and Design: Clinical-record based study, carried out retrospectively in post-pandemic period on subject′s case-sheets who had been quarantined at IG International Airport′s quarantine center at Delhi. Materials and Methods: Clinical scoring of each suspected case was done by studying their case record sheet and compared with the results of RT-PCR. RT-PCR was used to confirm the diagnosis (Gold Standard. Statistical Analysis: We calculated sensitivity, specificity, positive and negative predictive values of the clinical feature-based scoring system (the proposed new screening tool at different cut-off values. The most discriminant cut-off value was determined by plotting the ROC curve. Results: Of the 638 suspected cases, 127 (20% were confirmed to have H1N1 by RT-PCR examination. On the basis of ROC, the most discriminant clinical feature score for diagnosing Influenza A was found to be 7, which yielded sensitivity, specificity, positive, and negative predictive values of 86%, 88%, 64%, and 96%, respectively. Conclusion: The clinical features scoring system (CFSS can be used as a valid and cost-effective tool for screening swine flu (influenza A (H1N1 cases from large number of influenza-like illness suspects.

  14. An automatic machine learning system for coronary calcium scoring in clinical non-contrast enhanced, ECG-triggered cardiac CT

    Science.gov (United States)

    Wolterink, Jelmer M.; Leiner, Tim; Takx, Richard A. P.; Viergever, Max A.; Išgum, Ivana

    2014-03-01

    Presence of coronary artery calcium (CAC) is a strong and independent predictor of cardiovascular events. We present a system using a forest of extremely randomized trees to automatically identify and quantify CAC in routinely acquired cardiac non-contrast enhanced CT. Candidate lesions the system could not label with high certainty were automatically identified and presented to an expert who could relabel them to achieve high scoring accuracy with minimal effort. The study included 200 consecutive non-contrast enhanced ECG-triggered cardiac CTs (120 kV, 55 mAs, 3 mm section thickness). Expert CAC annotations made as part of the clinical routine served as the reference standard. CAC candidates were extracted by thresholding (130 HU) and 3-D connected component analysis. They were described by shape, intensity and spatial features calculated using multi-atlas segmentation of coronary artery centerlines from ten CTA scans. CAC was identified using a randomized decision tree ensemble classifier in a ten-fold stratified cross-validation experiment and quantified in Agatston and volume scores for each patient. After classification, candidates with posterior probability indicating uncertain labeling were selected for further assessment by an expert. Images with metal implants were excluded. In the remaining 164 images, Spearman's p between automatic and reference scores was 0.94 for both Agatston and volume scores. On average 1.8 candidate lesions per scan were subsequently presented to an expert. After correction, Spearman's p was 0.98. We have described a system for automatic CAC scoring in cardiac CT images which is able to effectively select difficult examinations for further refinement by an expert.

  15. High resolution computed tomography of the chest in cystic fibrosis (CF): is simplification of scoring systems feasible?

    Energy Technology Data Exchange (ETDEWEB)

    Oikonomou, Anastasia; Prassopoulos, Panos [University Hospital of Alexandroupolis, Democritus University of Thrace, Department of Radiology, Dragana, Alexandroupolis (Greece); Tsanakas, John; Hatziagorou, Elpis; Kirvassilis, Fotios [Ippokratio Hospital of Thessaloniki, Aristotle University of Thessaloniki, 3d Department of Pediatrics, Thessaloniki (Greece); Efremidis, Stavros [University Hospital of Ioannina, University of Ioannina, Department of Radiology, Ioannina (Greece)

    2008-03-15

    The purpose of this study was to simplify HRCT scoring systems (SS) for CF by selecting representative HRCT parameters. Forty-two consecutive patients with CF underwent baseline and follow-up chest HRCT. Three radiologists evaluated 84 HRCTs employing five SS. ''Simplified'' HRCT SS were formed by selection of parameters exhibiting statistically significant relations with FEV1. Pulmonary function tests (PFTs) and nutrition (IBW%) were recorded. Regression analysis, Pearson correlation and T-test were used for statistical analysis. Three HRCT parameters were selected for the formation of ''simplified'' HRCT SS (severity of bronchiectasis, bronchial wall thickening, atelectasis-consolidation) using regression analysis. There was excellent correlation between each ''simplified'' and corresponding complete score (0.892 < r < 0.0967, p < 0.0001) or the remaining four complete scores (0.786 < r < 0.961, p < 0.0001). Strong correlation was found among the five ''simplified'' scores (0.803 < r < 0.997, p < 0.0001). Comparing baseline complete and ''simplified'' scores with corresponding follow-up ones, significant worsening was observed (p < 0.0001). PFTs and IBW% did not change significantly. HRCT scores correlated moderately with FVC and FEV1, but there was no correlation with FEF25-75 and IBW%. ''Simplified'' HRCT SS are as reliable as the complete ones and detect progression of lung disease earlier than clinical parameters. They are easy to use and could be adopted in clinical practice. (orig.)

  16. NIKEI: a new inexpensive and non-invasive scoring system to exclude advanced fibrosis in patients with NAFLD.

    Directory of Open Access Journals (Sweden)

    Münevver Demir

    Full Text Available AIMS: To develop, validate and compare a non-invasive fibrosis scoring system for non-alcoholic fatty liver disease (NAFLD derived from routinely obtained clinical and biochemical parameters. METHODS: 267 consecutive patients with biopsy proven fatty liver or non-alcoholic steatohepatitis were randomly assigned to the estimation (2/3 or validation (1/3 group to develop a model for the prediction of advanced fibrosis. Univariate statistics were performed to compare patients with and without advanced fibrosis, and following a multivariate logistic regression analysis a new scoring system was constructed. This non-invasive Koeln-Essen-index (NIKEI was validated and compared to the FIB-4 index by calculating the area under the receiver operating characteristic curve (AUC. We evaluated a stepwise combination of both scoring systems for the precise prediction of advanced fibrosis. To set in contrast, we additionally tested the diagnostic accuracy of the AST/ALT ratio, BARD score and the NAFLD fibrosis score in our cohort. RESULTS: Age, AST, AST/ALT ratio, and total bilirubin were identified as significant predictors of advanced fibrosis and used to construct the NIKEI with an AUC of 0.968 [0.937; 0.998] compared to 0.929 [0.869; 0.989] for the FIB-4 index. The absence of advanced fibrosis could be confirmed with excellent accuracy (99-100%. The positive predictive value of the FIB-4 index was higher (100% vs. 60%, however, the false negative rate was also high (33%. With a stepwise combination of both indices 82%-84% of biopsies would have been avoidable without a single misclassification. The AUROC for AST/ALT ratio, the NAFLD fibrosis score, and the BARD score were 0.81 (95% CI, 0.72-0.90, 0.96 (95% CI 0.92-0.99, and 0.67 (95% CI 0.55-0.78, respectively. CONCLUSION: The NIKEI can reliably exclude advanced fibrosis in subjects with NAFLD. In combination with the FIB-4 index misclassification with inadequate clinical management can be avoided while

  17. Landing Error Scoring System Differences Between Single-Sport and Multi-Sport Female High School–Aged Athletes

    Science.gov (United States)

    Beese, Mark E.; Joy, Elizabeth; Switzler, Craig L.; Hicks-Little, Charlie A.

    2015-01-01

    Context Single-sport specialization (SSS) is becoming more prevalent in youth athletes. Deficits in functional movement have been shown to predispose athletes to injury. It is unclear whether a link exists between SSS and the development of functional movement deficits that predispose SSS athletes to an increased risk of knee injury. Objective To determine whether functional movement deficits exist in SSS athletes compared with multi-sport (M-S) athletes. Design Cross-sectional study. Setting Soccer practice fields. Patients or Other Participants A total of 40 (21 SSS [age = 15.05 ± 1.2 years], 19 M-S [age = 15.32 ± 1.2 years]) female high school athlete volunteers were recruited through local soccer clubs. All SSS athletes played soccer. Intervention(s) Participants were grouped into 2 categories: SSS and M-S. All participants completed 3 trials of the standard Landing Error Scoring System (LESS) jump-landing task. They performed a double-legged jump from a 30-cm platform, landing on a rubber mat at a distance of half their body height. Upon landing, participants immediately performed a maximal vertical jump. Main Outcome Measure(s) Values were assigned to each trial using the LESS scoring criteria. We averaged the 3 scored trials and then used a Mann-Whitney U test to test for differences between groups. Participant scores from the jump-landing assessment for each group were also placed into the 4 defined LESS categories for group comparison using a Pearson χ2 test. The α level was set a priori at .05. Results Mean scores were 6.84 ± 1.81 for the SSS group and 6.07 ± 1.93 for the M-S group. We observed no differences between groups (z = −1.44, P = .15). A Pearson χ2 analysis revealed that the proportions of athletes classified as having excellent, good, moderate, or poor LESS scores were not different between the SSS and M-S groups ( = 1.999, P = .57). Conclusions Participation in soccer alone compared with multiple sports did not affect LESS scores in

  18. The Validity of a Scoring System in Predicting Intravenous Immunoglobulin Treatment Failure in Children With Kawasaki Disease

    Directory of Open Access Journals (Sweden)

    Nateghian

    2015-12-01

    Full Text Available Background Between 10 and 20% of children with Kawasaki disease (KD will not respond to intravenous immunoglobulin (IVIG treatment, and are prone to coronary abnormalities. A variety of predicting scoring systems, including the Kobayashi system, have been proposed, but have not yet been evaluated using Iranian patients. Objectives To evaluate the Kobayashi scoring system with regard to predicting response to IVIG treatment in Iranian children. Patients and Methods All patients who received a final diagnosis of KD at Aliasghar children’s hospital between 1982 and 2013, and who met the inclusion criteria, were enrolled in this retrospective cohort study. We excluded patients with missing data, abnormal echocardiographic finding on admission, late admission, atypical or afebrile cases, and those who had received an insufficient amount of IVIG. We compared demographic and echocardiographic data before IVIG, and within 7 days of treatment, as well as C reactive protein (CRP, sodium, aspartate aminotransferase, platelet levels, neutrophil percentage, age of patients, and duration of fever before IVIG administration, in treatment responders and non-responders. Results Of the 141 cases, 97 patients met the criteria and were enrolled. Of these, 19 (19.6% did not respond to IVIG. A total of 61.8% of patients were male, and the mean patient age was 36.9 months (SD = 32.1 months. Echocardiographic evaluation revealed early coronary involvement in 15.3% of patients, and coronary abnormalities were diagnosed in 10% of patients within the first 10 days of presentation and concurrent with their IVIG treatment. A between-groups comparison of quantitative CRP, absolute neutrophil count, and platelet count showed that platelet count alone was significantly higher in nonresponders (P = 0.04. With regard to items of Kobayashi scoring system, data were present for just 41 cases, but a significant difference between the two groups was shown, with the treatment

  19. Establishment and validation of an updated diagnostic FCM scoring system based on pooled immunophenotyping in CD34+ blasts and its clinical significance for myelodysplastic syndromes.

    Directory of Open Access Journals (Sweden)

    Feng Xu

    Full Text Available Abnormal immunophenotypes of hematopoietic cells can be detected by flow cytometry (FCM to assist the diagnosis of myelodysplastic syndromes (MDS. We previously established a FCM scoring system for the diagnosis of low-grade MDS. In this study, additional valuable antigens were involved in an updated FCM scoring system (u-FCMSS for all MDS subtypes. The u-FCMSS showed better sensitivity and specificity (89.4% and 96.5% in distinguishing MDS from non-clonal cytopenia diseases. Validation analysis of u-FCMSS exhibited comparable sensitivity and specificity (86.7% and 93.3% and high agreement rate (88.9% of FCM diagnosis with morphological diagnosis at optimal cut-off (score 3. The distribution of FCM scores in different disease stages was also analyzed. The results suggested that early scoring from abnormal expression of mature myeloid/lymphoid antigens and advanced scoring from abnormal expression of stem/progenitor antigens expression constituted the majority of FCM scores of low-grade and high-grade MDS, respectively. High early scoring was generally accompanied by low IPSS-R score and superior survival, whereas high advanced scoring was accompanied by high IPSS-R score and inferior survival. In addition, the low-risk MDS patients with high early scoring and low advanced scoring were revealed as candidates for immunosuppressive therapy, whereas those with high advanced scoring and low early scoring may be more suitable for decitabine treatment. In conclusion, the u-FCMSS is a useful tool for diagnosis, prognosis and treatment selection in MDS. Differences in classes of antigens expressed and in distribution of FCM scores may reflect distinctive stage characteristics of MDS during disease progression.

  20. Validation of a new scoring system for the assessment of clinical trial research of oral mucositis induced by radiation or chemotherapy

    NARCIS (Netherlands)

    Sonis, ST; Eilers, JP; Epstein, JB; LeVeque, FG; Liggett, WH; Mulagha, MT; Peterson, DE; Rose, AH; Schubert, MM; Spijkervet, FK; Wittes, JP

    1999-01-01

    BACKGROUND. An impediment to mucositis research has been the lack of an accepted, validated scoring system. The objective of this study was to design, test, and validate a new scoring system for mucositis that can be used easily, is reproducible, and provides an accurate system for research applicat

  1. Brochopulmonary dysplasia: New high resolution computed tomography scorting system and correlation between the high resolution computed tomography score and clinical severity

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Sumi; Kim, Woo Sun; Cheon, Jung Eun; Kim, Han Suk; Lee, Whal; Jung, Ah Young; Kim, In One; Choi, Jung Hwan [Seoul National University College of Medicine, Seoul (KR)

    2013-04-15

    To develop an high resolution computed tomography (HRCT) scoring system for the assessment of bronchopulmonary dysplasia (BPD) and determine its usefulness as compared with the chest radiographic score. Forty-two very low-birth-weight preterm infants with BPD (25 male, 17 female) were prospectively evaluated with HRCT performed at the mean age of 39.1-week postmenstrual age. Clinical severity of BPD was categorized as mild, moderate or severe. The HRCT score (0-36) of each patient was the sum of the number of bronchopulmonary segments with 1) hyperaeration and 2) parenchymal lesions (linear lesions, segmental atelectasis, consolidation and architectural distortion), respectively. We compared the HRCT scores with the chest radiographic scores (the Toce system) in terms of correlation with clinical severity. The HRCT score had good interobserver (r = 0.969, p < 0.001) and intraobserver (r = 0.986, p < 0.001) reproducibility. The HRCT score showed better correlation (r = 0.646, p < 0.001) with the clinical severity of BPD than the chest radiographic score (r = 0.410, p = 0.007). The hyperaeration score showed better correlation (r = 0.738, p < 0.001) with the clinical severity of BPD than the parenchymal score (r = 0.523, p < 0.001). We have developed a new HRCT scoring system for BPD based on the quantitative evaluation of pulmonary abnormalities of BPD consisting of the hyperaeration score and the parenchymal score. The HRCT score shows better correlation with the clinical severity of BPD than the radiographic score.

  2. Balthazar computed tomography severity index is superior to Ranson criteria and APACHE Ⅱ scoring system in predicting acute pancreatitis outcome

    Institute of Scientific and Technical Information of China (English)

    Ting-Kai Leung; Chi-Ming Lee; Shyr-Yi Lin; Hsin-Chi Chen; Hung-Jung Wang; Li-Kuo Shen; Ya-Yen Chen

    2005-01-01

    AIM: Acute pancreatitis (AP) is a process with variable involvement of regional tissues or organ systems.Multifactorial scales included the Ranson, Acute Physiology and Chronic Health Evaluation (APACHE Ⅱ) systems and Balthazar computed tomography severity index (CTSI).The purpose of this review study was to assess the accuracy of CTSI, Ranson score, and APACHE Ⅱ score in course and outcome prediction of AP.METHODS: We reviewed 121 patients who underwent helical CT within 48 h after onset of symptoms of a first episode of AP between 1999 and 2003. Fourteen inappropriate subjects were excluded; we reviewed the 107 contrastenhanced CT images to calculate the CTSI. We also reviewed their Ranson and APACHE Ⅱ score. In addition, complications,duration of hospitalization, mortality rate, and other pathology history also were our comparison parameters.RESULTS: We classified 85 patients (79%) as having mild AP (CTSI <5) and 22 patients (21%) as having severe AP (CTSI ≥5). In mild group, the mean APACHE Ⅱ score and Ranson score was 8.6±1.9 and 2.4±1.2, and those of severe group was 10.2±2.1 and 3.1±0.8, respectively. The most common complication was pseudocyst and abscess and it presented in 21 (20%) patients and their CTSI was 5.9±1.4. A CTSI ≥5 significantly correlated with death,complication present, and prolonged length of stay.Patients with a CTSI ≥5 were 15 times to die than those CTSI <5, and the prolonged length of stay and complications present were 17 times and 8 times than that in CTSI <5,respectively.CONCLUSION: CTSI is a useful tool in assessing the severity and outcome of AP and the CTSI ≥5 is an index in our study. Although Ranson score and APACHE Ⅱ score also are choices to be the predictors for complications,mortality and the length of stay of AP, the sensitivity of them are lower than CTSI.

  3. Earlier application of percutaneous cardiopulmonary support rescues patients from severe cardiopulmonary failure using the APACHE III scoring system.

    Science.gov (United States)

    Song, Suk-Won; Yang, Hong-Suk; Lee, Sak; Youn, Young-Nam; Yoo, Kyung-Jong

    2009-12-01

    Percutaneous cardiopulmonary support (PCPS) is a widely accepted treatment for severe cardiopulmonary failure. This system, which uses a percutaneous approach and autopriming devices, can be rapidly applied in emergency situations. We sought to identify the risk factors that could help predict in-hospital mortality, and to assess its outcomes in survivors. During a 2-yr period, 50 patients underwent PCPS for the treatment of severe cardiopulmonary failure, and of those, 22 (44%) were classified as survivors and 28 (56%) as non-survivors. We compared the 2 groups for risk factors of in-hospital mortality and to establish proper PCPS timing. Twenty patients underwent PCPS for acute myocardial infarction, 20 for severe cardiopulmonary failure after cardiac surgery, 7 for acute respiratory distress syndrome, and 3 for acute myocarditis. Multivariate analysis showed that an acute physiology, age, and chronic health evaluation (APACHE) III score >or=50 prior to PCPS was the only significant predictor of in-hospital mortality (P=0.001). Overall 18-month survival was 42.2%. Cox analysis showed patients with APACHE III scores >or=50 had a poor prognosis (P=0.001). Earlier application of PCPS, and other preemptive strategies designed to optimize high-risk patients, may improve patient outcomes. Identifying patients with high APACHE scores at the beginning of PCPS may predict in-hospital mortality. Survivors, particularly those with higher APACHE scores, may require more frequent follow-up to improve overall survival.

  4. Brasfield and Wisconsin scoring systems have equal value as outcome assessment tools of cystic fibrosis lung disease

    Energy Technology Data Exchange (ETDEWEB)

    Cleveland, Robert H.; Stamoulis, Catherine; Sawicki, Gregory; Kelliher, Emma; Wood, Christopher; Zurakowski, David; Lee, Edward [Boston Children' s Hospital, Harvard Medical School, Department of Radiology, Boston, MA (United States); Zucker, Evan J. [Tufts Medical School, Boston, MA (United States)

    2014-05-15

    Several imaging-based scoring systems have been used as outcome measures in assessing the severity of cystic fibrosis (CF) lung disease. It has been shown that chest radiography performs equally to computed tomography (CT). There is the opinion that of the two most commonly used chest radiograph (CXR) systems, the Brasfield system is less sensitive and reliable than the Wisconsin system. This report assesses the reproducibility and reliability of the two systems. Thirty patients with CXRs during a 5-year period were randomly selected. One hundred eighty-two studies had data for all CXRs and pulmonary function tests (PFTs), Forced Expiratory Volume in One Second (FEV-1) and Forced Vital Capacity (FVC). PFT values closest to the date of each CXR were recorded. Four radiologists scored each image twice by both the Brasfield and Wisconsin systems. Intra- and inter-rater reliability, correlation with PFTs and direct correlation of the two systems were calculated. Intra-rater agreement: r = 0.86-0.99 Brasfield, r = 0.78-0.96 Wisconsin. Inter-rater agreement: 0.76-0.90 Brasfield, r = 0.74-0.97 Wisconsin. Brasfield vs. FEV-1: r = 0.55, vs. FVC r = 0.61. Wisconsin vs. FEV-1: r = 0.57, vs. FVC r = 0.66. Correlation of the two systems: r = 0.86 (all P < 0.001). The Brasfield and Wisconsin systems performed very similarly providing equally reproducible, robust and reliable measures. (orig.)

  5. Brasfield and Wisconsin scoring systems have equal value as outcome assessment tools of cystic fibrosis lung disease

    International Nuclear Information System (INIS)

    Several imaging-based scoring systems have been used as outcome measures in assessing the severity of cystic fibrosis (CF) lung disease. It has been shown that chest radiography performs equally to computed tomography (CT). There is the opinion that of the two most commonly used chest radiograph (CXR) systems, the Brasfield system is less sensitive and reliable than the Wisconsin system. This report assesses the reproducibility and reliability of the two systems. Thirty patients with CXRs during a 5-year period were randomly selected. One hundred eighty-two studies had data for all CXRs and pulmonary function tests (PFTs), Forced Expiratory Volume in One Second (FEV-1) and Forced Vital Capacity (FVC). PFT values closest to the date of each CXR were recorded. Four radiologists scored each image twice by both the Brasfield and Wisconsin systems. Intra- and inter-rater reliability, correlation with PFTs and direct correlation of the two systems were calculated. Intra-rater agreement: r = 0.86-0.99 Brasfield, r = 0.78-0.96 Wisconsin. Inter-rater agreement: 0.76-0.90 Brasfield, r = 0.74-0.97 Wisconsin. Brasfield vs. FEV-1: r = 0.55, vs. FVC r = 0.61. Wisconsin vs. FEV-1: r = 0.57, vs. FVC r = 0.66. Correlation of the two systems: r = 0.86 (all P < 0.001). The Brasfield and Wisconsin systems performed very similarly providing equally reproducible, robust and reliable measures. (orig.)

  6. Implementation of a Pediatric Early Warning Scoring System at an Academic Medical Center.

    Science.gov (United States)

    Douglas, Kimberly; Collado, Jerry Christopher; Keller, Sheila

    2016-01-01

    Despite the addition of family-activated rapid response to the rapid response team algorithm, a children's hospital did not see an increase in utilization of the pediatric rapid response team. A Pediatric Early Warning Score in non-ICU pediatric inpatient units was implemented to increase the number of rapid response team activations. A retrospective review of the 130-bed facility, over a 12-month period, revealed an increase in pediatric rapid response calls, with a subsequent decrease in code team activations. The authors outline implementation strategies and discuss barriers encountered throughout the process, along with implications for nurse leaders. PMID:27575799

  7. Implementation of a Pediatric Early Warning Scoring System at an Academic Medical Center.

    Science.gov (United States)

    Douglas, Kimberly; Collado, Jerry Christopher; Keller, Sheila

    2016-01-01

    Despite the addition of family-activated rapid response to the rapid response team algorithm, a children's hospital did not see an increase in utilization of the pediatric rapid response team. A Pediatric Early Warning Score in non-ICU pediatric inpatient units was implemented to increase the number of rapid response team activations. A retrospective review of the 130-bed facility, over a 12-month period, revealed an increase in pediatric rapid response calls, with a subsequent decrease in code team activations. The authors outline implementation strategies and discuss barriers encountered throughout the process, along with implications for nurse leaders.

  8. Precise prediction model and simplified scoring system for sustained combined response to interferon-α

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    AIM:To establish a predictive algorithm which may serve for selecting optimal candidates for interferon-α(IFN-α) treatment.METHODS:A total of 474 IFN-α treated hepatitis B virus e antigen(HBeAg)-positive patients were enrolled in the present study.The patients' baseline characteristics,such as age,gender,blood tests,activity grading(G) of intrahepatic inflammation,score(S) of liver fibrosis,hepatitis B virus(HBV) DNA and genotype were evaluated;therapy duration and response of each patient at the 24th wk af...

  9. Palliative Care Medical Education in European Universities: A descriptive study and numerical scoring system proposal for assessing educational development

    OpenAIRE

    Carrasco-Gimeno, J. (Jose Miguel); Lynch, T. J.; Garralda-Domezain, E. (Eduardo); Woitha, K.; Elsner, F.; Filbet, M.; Ellershaw, J E; Clark, D; Centeno-Cortés, C. (Carlos)

    2015-01-01

    Context: The lack of palliative medicine (PM) education has been identified as a barrier to the development of the discipline. A number of international institutions have called for its implementation within undergraduate medical curricula. Objectives: The objectives are to describe the situation of undergraduate PM education in Europe and to propose a scoring system to evaluate its status. Methods: This descriptive study was conducted with data provided by key experts fro...

  10. Inflammatory response related scoring systems in assessing the prognosis of patients with pancreatic ductal adenocarcinoma:a systematic review

    Institute of Scientific and Technical Information of China (English)

    Jawad Ahmad; Nathan Grimes; Shahid Farid; Gareth Morris-Stiff

    2014-01-01

    BACKGROUND: Various scoring systems based on assessment of the systemic inflammatory response help assessing the prognosis of patients with pancreatic ductal adenocarcinoma. In the present systematic review we evaluated the validity of four pre-intervention scoring systems: Glasgow prognostic score (GPS) and its modified version (mGPS), platelet lymphocyte ratio (PLR), neutrophil lymphocyte ratio (NLR), and prognostic nutrition index (PNI). DATA SOURCES: MOOSE guidelines were followed and EMBASE and MEDLINE databases were searched for all published studies until September 2013 using comprehensive text word and MeSH terms. All identified studies were analyzed, and relevant studies were included in the systematic review. RESULTS: Six studies were identified for GPS/mGPS with 3 reporting statistical significance for GPS/mGPS on both univariate analysis (UVA) and multivariate analysis (MVA). Two studies suggested prognostic significance on UVA but not MVA, and in the final study UVA failed to show significance. Eleven studies evaluated the prognostic value of NLR. Six of them reported prognostic significance for NLR on UVA that persisted at MVA in 4 studies, and in the remaining 2 studies NLR was the only significant factor on UVA. In the remaining 5 studies, all in patients undergoing resection, there was no significance on UVA. Seven studies evaluated PLR, with only one study demonstrated its prognostic significance on both UVA and MVA, the rest did not show the significance on UVA. Of the two studies identified for PNI, one demonstrated a statistically significant difference in survival on both UVA and MVA, and the other reported no significance for PNI on UVA. CONCLUSIONS: Both GPS/mGPS and NLR may be useful but further better-designed studies are required to confirm their value. PLR might be little useful, and there are at present inadequate data to assess the prognostic value of PNI. At present, no scoring system is reliable enough to be accepted into routine use

  11. [Comparative study of the Interplak tooth cleansing instrument].

    Science.gov (United States)

    Schwarz, P; Benz, C; Sonnabend, E

    1990-09-01

    Unlike manual and electric toothbrushes, the brush head of the Interplak instruments remains stationary while ten tufts of bristle rotate. The efficacy of this new system was evaluated in comparison to a conventional electric toothbrush (Braun dental d3). When used for the first time the Interplak instrument proved to be more effective in reducing plaque. After training periods of 2 and 4 weeks there was, however, no significant difference between products. PMID:2269193

  12. How I handled ambiguity in a system to read music scores

    Science.gov (United States)

    Ruttenberg, Alan

    1992-11-01

    In a program for reading printed music, a variety of low level feature detectors were used to extract sufficient information to reconstruct the score. All feature detectors were unreliable to some extent, and were biased towards yielding false positives rather than missing features. In order to reconstruct the score, conflicting information from the feature detectors needed to be recognized and eliminated. All objects as well as their geometric and semantic relations were represented in an object oriented framework. Ambiguity (implemented as a generic predicate) was defined -- and explicitly represented -- in terms of these relationships. Examples of ambiguous relationships include: An accidental and a note head having an on-top-of geometric relationship, or the total duration of notes in a measure not being equal to the notated time signature. A method inspired by Waltz filtering was used to produce a consistent, unambiguous interpretation. Waltz filtering is a symbolic constraint propagation technique which has been applied to line drawings. During interpretation attention was focused on objects which had ambiguous relations. Ambiguity was iteratively reduced or removed by using a variety of methods employing information gathered from local unambiguous relations.

  13. 'F- F- Felt it': Breathing Feminist, Queer and Clown Thinking into the Practice and Study of Sarah Kane’s Cleansed and Blasted

    OpenAIRE

    Kane, Nina R.

    2013-01-01

    This thesis uses studio practice, scholarly research, close reading of text, performance observation and conversation with practitioners to establish diverse readings of Sarah Kane’s Cleansed. It includes original material from the 2012 productions of Cleansed in Japan (Kamome-za Fringe Theatre), and in Ireland (Bare Cheek Theatre). It notes practice on Cleansed in gallery spaces (Cast-Off Drama, UK). It offers a dramaturgical approach to workshopping the play from a feminist and queer positi...

  14. Automated Data Cleansing in Data Harvesting and Data Migration

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Mark; Vowell, Lance; King, Ian; Augustus, Chris

    2011-03-16

    In the proposal for this project, we noted how the explosion of digitized information available through corporate databases, data stores and online search systems has resulted in the knowledge worker being bombarded by information. Knowledge workers typically spend more than 20-30% of their time seeking and sorting information, only finding the information 50-60% of the time . This information exists as unstructured, semi-structured and structured data. The problem of information overload is compounded by the production of duplicate or near-duplicate information. In addition, near-duplicate items frequently have different origins, creating a situation in which each item may have unique information of value, but their differences are not significant enough to justify maintaining them as separate entities. Effective tools can be provided to eliminate duplicate and near-duplicate information. The proposed approach was to extract unique information from data sets and consolidation that information into a single comprehensive file.

  15. Score Correlation

    OpenAIRE

    Fabián, Z. (Zdeněk)

    2010-01-01

    In this paper, we study a distribution-dependent correlation coefficient based on the concept of scalar score. This new measure of association of continuous random variables is compared by means of simulation experiments with the Pearson, Kendall and Spearman correlation coefficients.

  16. Assessment of a credit scoring system for popular bank savings and credit

    Directory of Open Access Journals (Sweden)

    José Francisco Martínez Sánchez

    2016-01-01

    Full Text Available El sistema bancario actual no cubre las necesidades de servicios financieros, y en particular de créditos, a los sectores más desfavorecidos de la sociedad. La presencia bancaria se localiza fundamentalmente en las ciudades y regiones con actividad económica importante, y para atender a estos sectores excluidos se han creado de forma natural, pero sin supervisión ni soporte de la autoridad, entidades financieras como las cajas populares, cooperativas, sociedades financieras populares, entre otras, que en conjunto se denominan entidades de ahorro y crédito popular. Sin embargo, la mayoría de este tipo de instituciones no son reconocidas ni supervisadas por la CNBV, lo cual se traduce en riesgos tanto para los usuarios de los servicios como para las instituciones financieras, destacando las ineficiencias en sus procesos de otorgamiento de créditos, ya que las decisiones de aceptar o no una solicitud de crédito se sustentan en el conocimiento, la experiencia y el criterio del analista de crédito. Este trabajo presenta la evaluación de un sistema de credit scoring , tanto en términos de costo-eficiencia para las entidades de ahorro y crédito, en especial para las SOFIPOS, como en términos de costo-beneficio para el proveedor de los servicios de evaluación de solicitudes de crédito. Como se mostrará en el desarrollo del trabajo, un modelo de esta naturaleza hace más eficiente el proceso crediticio a un costo razonable y es una inversión rentable para el proveedor de servicios de credit scoring.

  17. Comparison of pain scores between patients undergoing panretinal photocoagulation using navigated or pattern scan laser systems

    Directory of Open Access Journals (Sweden)

    Umit Ubeyt Inan

    2016-02-01

    Full Text Available ABSTRACT Purpose: To compare the pain responses of patients with proliferative diabetic retinopathy (PDR undergoing panretinal photocoagulation (PRP using either pattern scan laser (PASCAL or navigated laser photocoagulation (NAVILAS. Methods: Patients diagnosed with PDR were randomly assigned to undergo either PASCAL or NAVILAS photocoagulation treatment. PRP was performed using the multi-shot mode with a spot size of 200-400 µm and a pulse duration of 30 ms to obtain a white-grayish spot on the retina. Parameters were identical in both procedures. After 30 min of PRP application, patients were asked to verbally describe their pain perception as either "none," "mild," "moderate," "severe," or "very severe" using a verbal rating scale (VRS and visual analog scale (VAS by indicating a score from "0" to "10," representing the severity of pain from "no pain" to "severe pain." Results: A total of 60 eyes of 60 patients (20 females and 40 males diagnosed with PDR were treated. The mean age of patients was 62.22 ± 9.19 years, and the mean diabetes duration was 195.47 ± 94.54 months. The mean number of laser spots delivered during PRP was 389.47 ± 71.52 in the NAVILAS group and 392.70 ± 54.33 in the PASCAL group (p=0.57. The difference in pain responses between patients in the NAVILAS and PASCAL groups was significant with regard to the mean VRS (1.10 ± 0.67 and 1.47 ± 0.69, respectively; p=0.042 and mean VAS (2.13 ± 1.17 and 2.97 ± 1.35, respectively; p=0.034 scores. Conclusions: Pain responses in patients undergoing PRP with a 30-ms pulse duration were significantly milder in the NAVILAS group than in the PASCAL group.

  18. The Effect of Forming a Score-Based Competitive System in a Cyber-Drilling Atmosphere for Learning and Motivation

    Directory of Open Access Journals (Sweden)

    Bekir ÇELEN

    2009-01-01

    Full Text Available This research focuses on to carry out a structure, in which the desire of having a high score and seeing the name in the top list is used in web-based drills and helps students to be more willing in test solving. The purpose of this study is to determine the effects of web-based drills on motivation and learning in a competitive atmosphere. Furthermore, the study also attempts to determine if the students’ levels and frequency of using a computer have an effect on the test scores in a web based system.Over a period of two week application students logged in the system using their own passwords and solve questions whenever they wanted. The names and photographs of the students who achieved the best scores were declared on the school’s website. In the study, an experimental design has been applied. The data were collected through the database in the web-based drill, pre and post survey to determine the level of and the reasons for students’ use of the website and history common exam results. According to the findings of the research, the website that has the competitive atmosphere has a positive effect on students’ achievement in their lessons. The application led to a change in students’ aim to visit the website and the frequency of their visits.

  19. A scoring system based on artificial neural network for predicting 10-year survival in stage II A colon cancer patients after radical surgery

    Science.gov (United States)

    Jiang, Wu; Lu, Shi-Xun; Lu, Zhen-Hai; Li, Pei-Xing; Yun, Jing-Ping; Zhang, Rong-Xin; Pan, Zhi-Zhong; Wan, De-Sen

    2016-01-01

    Nearly 20% patients with stage II A colon cancer will develop recurrent disease post-operatively. The present study aims to develop a scoring system based on Artificial Neural Network (ANN) model for predicting 10-year survival outcome. The clinical and molecular data of 117 stage II A colon cancer patients from Sun Yat-sen University Cancer Center were used for training set and test set; poor pathological grading (score 49), reduced expression of TGFBR2 (score 33), over-expression of TGF-β (score 45), MAPK (score 32), pin1 (score 100), β-catenin in tumor tissue (score 50) and reduced expression of TGF-β in normal mucosa (score 22) were selected as the prognostic risk predictors. According to the developed scoring system, the patients were divided into 3 subgroups, which were supposed with higher, moderate and lower risk levels. As a result, for the 3 subgroups, the 10-year overall survival (OS) rates were 16.7%, 62.9% and 100% (P < 0.001); and the 10-year disease free survival (DFS) rates were 16.7%, 61.8% and 98.8% (P < 0.001) respectively. It showed that this scoring system for stage II A colon cancer could help to predict long-term survival and screen out high-risk individuals for more vigorous treatment. PMID:27008710

  20. A scoring system based on artificial neural network for predicting 10-year survival in stage II A colon cancer patients after radical surgery.

    Science.gov (United States)

    Peng, Jian-Hong; Fang, Yu-Jing; Li, Cai-Xia; Ou, Qing-Jian; Jiang, Wu; Lu, Shi-Xun; Lu, Zhen-Hai; Li, Pei-Xing; Yun, Jing-Ping; Zhang, Rong-Xin; Pan, Zhi-Zhong; Wan, De Sen

    2016-04-19

    Nearly 20% patients with stage II A colon cancer will develop recurrent disease post-operatively. The present study aims to develop a scoring system based on Artificial Neural Network (ANN) model for predicting 10-year survival outcome. The clinical and molecular data of 117 stage II A colon cancer patients from Sun Yat-sen University Cancer Center were used for training set and test set; poor pathological grading (score 49), reduced expression of TGFBR2 (score 33), over-expression of TGF-β (score 45), MAPK (score 32), pin1 (score 100), β-catenin in tumor tissue (score 50) and reduced expression of TGF-β in normal mucosa (score 22) were selected as the prognostic risk predictors. According to the developed scoring system, the patients were divided into 3 subgroups, which were supposed with higher, moderate and lower risk levels. As a result, for the 3 subgroups, the 10-year overall survival (OS) rates were 16.7%, 62.9% and 100% (P < 0.001); and the 10-year disease free survival (DFS) rates were 16.7%, 61.8% and 98.8% (P < 0.001) respectively. It showed that this scoring system for stage II A colon cancer could help to predict long-term survival and screen out high-risk individuals for more vigorous treatment.

  1. Guidelines for maintenance treatment of childhood asthma: development of a score card system by multivariate cluster analysis.

    Science.gov (United States)

    Donnelly, W J; Donnelly, J E; Thong, Y H

    1987-01-01

    Multivariate cluster analysis of data on 128 asthmatic children resulted in the identification of 8 major discriminating variables. Stepwise divisions by this computer programme resulted in the formation of 6 grades of severity. There was significant correlation between higher grades of severity and early onset of the disease (P less than 0.02). There was also significant correlation between higher grades of severity and greater use of interval medications (P less than 0.002). However, 27.3% were receiving inadequate interval medications in respect of their grade of severity. Assignation of a 5-point scale to each of the 8 major discriminating variables resulted in the generation of computer-designated scores commensurate with each grade of severity. This was coupled to current recommendations for stepwise maintenance medications appropriate for each grade. This Score Card system for maintenance management of childhood asthma may prove useful in busy clinical settings.

  2. Assessment of the reliability in two groups of age, using the Qualitative Scoring System for the Bender Gestalt Test - Modified

    Directory of Open Access Journals (Sweden)

    César Ayax Merino Soto

    2011-01-01

    Full Text Available This study is looking for evidences of reliability, for the Qualification Qua- litative System (Brannigan y Brunner, 2002 applied to the Bender Gestalt Test – Modified. The participants were 86 children, divided in two groups: pre- school and school; and three students who scored the designs in both groups. The analysis was done in the final grade and the item. The results pointed to the good levels of results of external reliability and internal consistence in the pre- school group, while these levels were scored in the school group. These differences establish the relation between these two aspects of measurement error and the emphasis in an appropriate training of measurements that require the examiner’s judgments. We discussed our results considering the potential utility of this relative version of the Bender Gestalt Test for the clinical practice and investigation as well.

  3. Prognostic value of scores based on malnutrition or systemic inflammatory response in patients with metastatic or recurrent gastric cancer.

    Science.gov (United States)

    Sachlova, Milana; Majek, Ondrej; Tucek, Stepan

    2014-01-01

    Cancer patients are frequently affected by malnutrition and weight loss, which affects their prognosis, length of hospital stay, health care costs, quality of life and survival. Our aim was to assess the prognostic value of different scores based on malnutrition or systemic inflammatory response in 91 metastatic or recurrent gastric cancer patients considered for palliative chemotherapy at the Masaryk Memorial Cancer Institute. We investigated their overall survival according to the following measures: Onodera's Prognostic Nutritional Index (OPNI), Glasgow Prognostic Score (GPS), nutritional risk indicator (NRI), Cancer Cachexia Study Group (CCSG), as previously defined, and a simple preadmission weight loss. The OPNI, GPS, and CCSG provided very significant prognostic values for survival (log-rank test P value evaluation of patients' prognosis and should be part of a routine evaluation of patients to provide a timely nutrition support. PMID:25356861

  4. Infant skin-cleansing product versus water: A pilot randomized, assessor-blinded controlled trial

    Directory of Open Access Journals (Sweden)

    Cork Michael J

    2011-05-01

    Full Text Available Abstract Background The vulnerability of newborn babies' skin creates the potential for a number of skin problems. Despite this, there remains a dearth of good quality evidence to inform practice. Published studies comparing water with a skin-cleansing product have not provided adequate data to inform an adequately powered trial. Nor have they distinguished between babies with and without a predisposition to atopic eczema. We conducted a pilot study as a prequel to designing an optimum trial to investigate whether bathing with a specific cleansing product is superior to bathing with water alone. The aims were to produce baseline data which would inform decisions for the main trial design (i.e. population, primary outcome, sample size calculation and to optimize the robustness of trial processes within the study setting. Methods 100 healthy, full term neonates aged Results Forty nine babies were randomized to cleansing product, 51 to water. The 95% confidence intervals (CI for the average TEWL measurement at each time point were: whole sample at baseline: 10.8 g/m2/h to 11.7 g/m2/h; CP group 4 weeks: 10.9 g/m2/h to 13.3 g/m2/h; 8 weeks: 11.4 g/m2/h to 12.9 g/m2/h; W group 4 weeks:10.9 g/m2/h to 12.2 g/m2/h; 8 weeks: 11.4 g/m2/h to 12.9 g/m2/h. Conclusion This pilot study provided valuable baseline data and important information on trial processes. The decision to proceed with a superiority trial, for example, was inconsistent with our data; therefore a non-inferiority trial is recommended. Trial registration ISRCTN72285670

  5. Evaluating cleansing effects on trace elements and stable isotope values in feathers of oiled birds.

    Science.gov (United States)

    Valladares, Sonia; Moreno, Roćio; Jover, Lluis; Sanpera, Carola

    2010-01-01

    Feathers of seabirds are widely used as a nondestructive tissue for pollution monitoring of trace elements, as well as convenient samples for trophic ecology studies by means of stable isotope analysis (SIA). Nevertheless, feathers can be occasionally impregnated with oil from deliberate ship discharges and from massive oil spill accidents. The feather structure makes them effective traps for particles and are subject to external contamination. It is unknown to what extent the oil adhered to feathers can change trace element concentrations or stable isotope signatures. This study has two primary objectives: (1) to assess if there are differences between trace element concentrations and stable isotope signatures of oiled and clean feathers, and (2) to determine if the cleansing of oiled feathers using commonly applied techniques such as sodium hydroxide (NaOH) washes in combination with an organic solvent (hexane) is more effective than using NaOH alone. In order to do this, we analysed trace elements (Se, Hg, Pb, Cu and Zn) and stable isotopes (delta(13)C and delta(15)N) of individual feathers of yellow-legged gulls (Larus michahellis) which were affected by the 2002 Prestige oil spill in Galicia (NW Spain). Two sets of feathers were analysed, one group were oil-free (Control group) and the other had oil adhered to its surface (Oiled group). We expected to find differences between control and oiled feathers when cleaning exclusively with NaOH and no differences when using hexane. Our results did not show significant differences between Control and Oiled groups as a consequence of the cleansing method used. Unexpectedly, the additional cleansing with hexane resulted in decreasing selenium concentrations and increasing zinc and delta(15)N values in all groups of feathers. PMID:19731016

  6. Wound cleansing: a key player in the implementation of the TIME paradigm.

    Science.gov (United States)

    Pilcher, Matthew

    2016-03-01

    The concept of wound bed preparation can be implemented using the TIME paradigm. Chronic wounds are mostly characterised by prolonged inflammation and increased bioburden. Removal of wound biofilm and devitalised tissue, which is an ideal environment for bacterial growth, can help address the I in TIME. Wound cleansing aims to remove contaminants, debris, dressing remnants and superficial slough from the wound. Some wound cleansers contain surfactants, which reduce the surface tension of a liquid, enabling it to spread further over a surface. This article describes how these solutions can be used to debride the wound surface without damaging healthy cells. PMID:26949864

  7. Mortality and management of 96 shark attacks and development of a shark bite severity scoring system.

    Science.gov (United States)

    Lentz, Ashley K; Burgess, George H; Perrin, Karen; Brown, Jennifer A; Mozingo, David W; Lottenberg, Lawrence

    2010-01-01

    Humans share a fascination and fear of sharks. We predict that most shark attacks are nonfatal but require skilled, timely medical intervention. The development of a shark bite severity scoring scale will assist communication and understanding of such an injury. We retrospectively reviewed records of the prospectively maintained International Shark Attack File (ISAF) at the University of Florida. The ISAF contains 4409 investigations, including 2979 documented attacks, 96 of which have complete medical records. We developed a Shark-Induced Trauma (SIT) Scale and calculated the level of injury for each attack. Medical records were reviewed for the 96 documented shark attack victims since 1921. Calculated levels of injury in the SIT Scale reveal 40 Level 1 injuries (41.7%), 16 Level 2 injuries (16.7%), 18 Level 3 injuries (18.8%), 14 Level 4 injuries (14.6%), and eight Level 5 injuries (8.3%). The overall mortality of shark attacks was 8.3 per cent. However, SIT Scale Level 1 injuries comprised the greatest percentage of cases at 41.7 per cent. Injury to major vascular structures increases mortality and necessitates immediate medical attention and definitive care by a surgeon. Shark bites deserve recognition with prompt resuscitation, washout, débridement, and follow up for prevention of infection and closure of more complex wounds.

  8. Score System Study for Hand-Extended Noodle Quality Based on HMW-GS Index in Wheat Flour

    Institute of Scientific and Technical Information of China (English)

    KANG Zhi-yu; WANG Jian-jun; SHANG Xun-wu

    2007-01-01

    Hand-extended noodle, a special kind of noodle, requires particular quality flour to make it. High molecular weight glutenin subunits (HMW-GS) in wheat are important protein subunits, which affect flour quality. To improve breeding and selection efficiency of wheat varieties which are used in making hand-extended noodle, 100 spring wheat varieties were selected to study the importance of HMW-GS on noodle quality score indexes such as color, appearance, taste agreeability, toughness, stickiness, smoothness, taste, and total score, through methods of quantity theory and statistic evaluation. It was shown that the hand-extended noodle quality score of HMW-GS 1, 2*, N, 7, 7 + 8, 17 + 18, 22, 2 + 10, 2 +11, 2+ 12, 5 + 10, and 10 was 5.40, 5.35, 0, 2.55, 2.56, 9.19, 0.05, 0.15, 1.49, 1.14, 10.00, and 5.14, respectively. The score system for hand-extended noodle quality based on HMW-GS index included eight multiple linear regression equations (R2 > 0.98).Hence, using the HMW-GS composition, the eight hand-extended noodle quality indexes would be forecasted exactly.Results indicated that ideal subunit compositions of HMW-GS for this special usage were composition 1, 17 + 18, 5 + 10, or composition 2*, 17 + 18, 5 + 10. This standard could be used on variety selection in the early generation of breeding crosses. HMW-GS 2 + 10, 2 + 11, and 2 + 12 were the least desirable subunits for hand-extended noodle, which should be avoided in wheat variety selection aimed for hand-extended noodle flour use.

  9. A new extranodal scoring system based on the prognostically relevant extranodal sites in diffuse large B-cell lymphoma, not otherwise specified treated with chemoimmunotherapy.

    Science.gov (United States)

    Hwang, Hee Sang; Yoon, Dok Hyun; Suh, Cheolwon; Huh, Jooryung

    2016-08-01

    Extranodal involvement is a well-known prognostic factor in patients with diffuse large B-cell lymphomas (DLBCL). Nevertheless, the prognostic impact of the extranodal scoring system included in the conventional international prognostic index (IPI) has been questioned in an era where rituximab treatment has become widespread. We investigated the prognostic impacts of individual sites of extranodal involvement in 761 patients with DLBCL who received rituximab-based chemoimmunotherapy. Subsequently, we established a new extranodal scoring system based on extranodal sites, showing significant prognostic correlation, and compared this system with conventional scoring systems, such as the IPI and the National Comprehensive Cancer Network-IPI (NCCN-IPI). An internal validation procedure, using bootstrapped samples, was also performed for both univariate and multivariate models. Using multivariate analysis with a backward variable selection, we found nine extranodal sites (the liver, lung, spleen, central nervous system, bone marrow, kidney, skin, adrenal glands, and peritoneum) that remained significant for use in the final model. Our newly established extranodal scoring system, based on these sites, was better correlated with patient survival than standard scoring systems, such as the IPI and the NCCN-IPI. Internal validation by bootstrapping demonstrated an improvement in model performance of our modified extranodal scoring system. Our new extranodal scoring system, based on the prognostically relevant sites, may improve the performance of conventional prognostic models of DLBCL in the rituximab era and warrants further external validation using large study populations. PMID:27167532

  10. The relationship between observer-based toxicity scoring and patient assessed symptom severity after treatment for head and neck cancer. A correlative cross sectional study of the DAHANCA toxicity scoring system and the EORTC quality of life questionnaires

    DEFF Research Database (Denmark)

    Bonde Jensen, Anders; Grau, Cai; Jensen, Kenneth

    2006-01-01

    BACKGROUND AND PURPOSE: Morbidity is an important issue in cancer       research. The observer-based toxicity scoring system used by DAHANCA (the       Danish head and neck cancer study group) has proved itself sensitive to       differences in toxicity in a large randomised study, but like other......       toxicity scoring systems it has not been formally validated. Conversely,       the EORTC quality of life questionnaire (QLQ) has been validated as a tool       for collecting information about the consequences of disease and treatment       on the well being of cancer patients. The purpose of this study...... toxicity scoring system       and the EORTC QLQ correlated with several clinical endpoints. The       conceptually similar endpoints of the two methods correlated       significantly. The objective endpoints of the DAHANCA scoring system were       only correlated with quality of life endpoints to a very...

  11. The use of the Balanced ScoreCard (BSC) in the model for investment and evaluation of medical information systems.

    Science.gov (United States)

    Niss, K U

    1999-01-01

    This paper describes the use of the Balanced ScoreCard (BSC) in the MIEMIS meso-model (Model for Investment and Evaluation of Medical Information Systems). The scope of the MIEMIS model is to integrate the evaluation process into the whole lifecycle of an information system using both a prospective and a retrospective approach. We conclude, that the MIEMIS-model has benefited from implementing the BSC into the model due to the fact, that the BSC can support the project management work. This approach helps ensuring, that the new information systems are fulfilled according to the plan and with a balance between the four perspectives (financial, customer/user, internal, and innovation/learning perspective) to avoid that the financial aspect is the driving force in developing and implementing a new information system, for example.

  12. Handedness and behavioural inhibition system/behavioural activation system (BIS/BAS) scores: A replication and extension of Wright, Hardie, and Wilson (2009).

    Science.gov (United States)

    Beaton, Alan A; Kaack, Imogen H; Corr, Philip J

    2015-01-01

    The Annett Hand Preference Questionnaire (AHPQ) as modified by Briggs and Nebes was administered along with Carver and White's behavioural inhibition system (BIS) and behavioural activation system (BAS) scale and a shortened form of the Big Five personality questionnaire to 92 university students. After eliminating the data from five respondents who reported having changed handedness and one outlier, there was a significant sex difference in mean BIS scores, with females (n = 43) scoring higher than males (n = 43). Replicating the results of Wright, Hardie and Wilson, non-right-handers (n = 36) had significantly higher mean BIS score than right-handers (n = 50). Controlling for sex of participant, neuroticism and BAS sub-scale scores in hierarchical regression analyses left this BIS effect substantially unaffected. There was no handedness or sex difference on any of the three BAS sub-scales. Further analyses revealed no association between strength, as distinct from direction, of handedness and BIS (or BAS) scores. The findings are discussed with reference to recent developments in reinforcement sensitivity theory on which BIS/BAS variables are based. PMID:25697855

  13. Handedness and behavioural inhibition system/behavioural activation system (BIS/BAS) scores: A replication and extension of Wright, Hardie, and Wilson (2009).

    Science.gov (United States)

    Beaton, Alan A; Kaack, Imogen H; Corr, Philip J

    2015-01-01

    The Annett Hand Preference Questionnaire (AHPQ) as modified by Briggs and Nebes was administered along with Carver and White's behavioural inhibition system (BIS) and behavioural activation system (BAS) scale and a shortened form of the Big Five personality questionnaire to 92 university students. After eliminating the data from five respondents who reported having changed handedness and one outlier, there was a significant sex difference in mean BIS scores, with females (n = 43) scoring higher than males (n = 43). Replicating the results of Wright, Hardie and Wilson, non-right-handers (n = 36) had significantly higher mean BIS score than right-handers (n = 50). Controlling for sex of participant, neuroticism and BAS sub-scale scores in hierarchical regression analyses left this BIS effect substantially unaffected. There was no handedness or sex difference on any of the three BAS sub-scales. Further analyses revealed no association between strength, as distinct from direction, of handedness and BIS (or BAS) scores. The findings are discussed with reference to recent developments in reinforcement sensitivity theory on which BIS/BAS variables are based.

  14. Assessment of calibration curve in visual analysis by a scoring system using 99mTc-GSA liver scintigraphy

    International Nuclear Information System (INIS)

    With a view to improving the correlation of liver scintigraphy using 99mTc-DTPA-galactosyl human serum albumin (GSA) with hepatic function as indicated by indices such as LHL15, HH15, and laboratory data, the present study was carried out to set up a calibration curve (CC) for visual analysis. The application of 7 patterns of CC with different settings to a 1-min image (5 to 6 minutes after radiotracer injection) in 98 cases led to the preparation of 686 images whose correlation with hepatic function was examined by 15 observers via the grade classification of a five-point scoring system using visual analysis. The grade classification was as follows: grade 1 (faint cardiac blood-pool image), grade 2 (slight cardiac blood-pool image compared with liver uptake), grade 3 (almost the same appearance of cardiac blood-pool image and that of liver uptake), grade 4 (intense cardiac blood-pool image associated with possible liver uptake), and grade 5 (very slight liver uptake). The five-point scoring system could be used for CC slopes of 4.21, 4.79 and 2.79 (the above correlation was strongest for 4.21). The significance of inter-grade group differences in ICG-R15, LHL15 and heart/liver ratio was examined according to slope. With the CC slope of 4.21, a significant inter-grade group difference was observed between grades 1 and 2, grades 2 and 3, grades 3 and 4, and grades 4 and 5. In conclusion, when the value of the CC slope was 4.2, it was considered appropriate for grade classification on a five-point scoring system using visual analysis. (author)

  15. State and Local Efforts to Investigate the Validity and Reliability of Scores from Teacher Evaluation Systems

    Science.gov (United States)

    Herlihy, Corinne; Karger, Ezra; Pollard, Cynthia; Hill, Heather C.; Kraft, Matthew A.; Williams, Megan; Howard, Sarah

    2014-01-01

    Context: In the past two years, states have implemented sweeping reforms to their teacher evaluation systems in response to Race to the Top legislation and, more recently, NCLB waivers. With these new systems, policymakers hope to make teacher evaluation both more rigorous and more grounded in specific job performance domains such as teaching…

  16. The Utility of the Balance Error Scoring System for Mild Brain Injury Assessments in Children and Adolescents

    OpenAIRE

    Quatman-Yates, Catherine; Hugentobler, Jason; Ammon, Robin; Mwase, Najima; Kurowski, Brad; Myer, Gregory D.

    2014-01-01

    The Balance Error Scoring System (BESS) is widely recognized as an acceptable assessment of postural control for adult patients following a mild traumatic brain injury (mTBI) or concussion. However, the measurement properties of the BESS as a post-mTBI assessment test for younger patients are not well understood. The purpose of this study was to evaluate the utility of the BESS as a post-mTBI assessment test for children and adolescents aged 8 to 18 years through 2 investigations: (1) a retro...

  17. Cleansing orthodontic brackets with air-powder polishing: effects on frictional force and degree of debris

    Science.gov (United States)

    Leite, Brisa dos Santos; Fagundes, Nathalia Carolina Fernandes; Aragón, Mônica Lídia Castro; Dias, Carmen Gilda Barroso Tavares; Normando, David

    2016-01-01

    ABSTRACT Introduction: Debris buildup on the bracket-wire interface can influence friction. Cleansing brackets with air-powder polishing can affect this process. Objective: The aim of this study was to evaluate the frictional force and amount of debris remaining on orthodontic brackets subjected to prophylaxis with air-powder polishing. Methods: Frictional force and debris buildup on the surface of 28 premolar brackets were evaluated after orthodontic treatment. In one hemiarch, each bracket was subjected to air-powder polishing (n = 14) for five seconds, while the contralateral hemiarch (n = 14) served as control. Mechanical friction tests were performed and images of the polished bracket surfaces and control surfaces were examined. Wilcoxon test was applied for comparative analysis between hemiarches at p < 0.05. Results: Brackets that had been cleaned with air-powder polishing showed lower friction (median = 1.27 N) when compared to the control surfaces (median = 4.52 N) (p < 0.01). Image analysis showed that the control group exhibited greater debris buildup (median = 2.0) compared with the group that received prophylaxis with air-powder polishing (median = 0.5) (p < 0.05). Conclusion: Cleansing orthodontic brackets with air-powder polishing significantly reduces debris buildup on the bracket surface while decreasing friction levels observed during sliding mechanics. PMID:27653265

  18. Systems view of adipogenesis via novel omics-driven and tissue-specific activity scoring of network functional modules

    Science.gov (United States)

    Nassiri, Isar; Lombardo, Rosario; Lauria, Mario; Morine, Melissa J.; Moyseos, Petros; Varma, Vijayalakshmi; Nolen, Greg T.; Knox, Bridgett; Sloper, Daniel; Kaput, Jim; Priami, Corrado

    2016-07-01

    The investigation of the complex processes involved in cellular differentiation must be based on unbiased, high throughput data processing methods to identify relevant biological pathways. A number of bioinformatics tools are available that can generate lists of pathways ranked by statistical significance (i.e. by p-value), while ideally it would be desirable to functionally score the pathways relative to each other or to other interacting parts of the system or process. We describe a new computational method (Network Activity Score Finder - NASFinder) to identify tissue-specific, omics-determined sub-networks and the connections with their upstream regulator receptors to obtain a systems view of the differentiation of human adipocytes. Adipogenesis of human SBGS pre-adipocyte cells in vitro was monitored with a transcriptomic data set comprising six time points (0, 6, 48, 96, 192, 384 hours). To elucidate the mechanisms of adipogenesis, NASFinder was used to perform time-point analysis by comparing each time point against the control (0 h) and time-lapse analysis by comparing each time point with the previous one. NASFinder identified the coordinated activity of seemingly unrelated processes between each comparison, providing the first systems view of adipogenesis in culture. NASFinder has been implemented into a web-based, freely available resource associated with novel, easy to read visualization of omics data sets and network modules.

  19. Serum calcium levels, TRPM7, TRPC1, microcalcifications, and breast cancer using breast imaging reporting and data system scores

    Directory of Open Access Journals (Sweden)

    Mandavilli S

    2012-12-01

    Full Text Available Shravya Mandavilli,1 Brij B Singh,2 Abe E Sahmoun11Department of Internal Medicine, University of North Dakota School of Medicine and Health Sciences, Fargo, ND, USA; 2Department of Biochemistry and Molecular Biology, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USABackground: An association between higher serum calcium (Ca2+ levels and breast cancer has been previously reported. However, little is known regarding the relationship between serum Ca2+ levels and the expression of Ca2+ channels in the presence of breast microcalcifications.Methods: A retrospective analysis of women newly diagnosed with breast microcalcifications was performed based on the Breast Imaging Reporting and Data System (BI-RADS. The expression of TRPC1, TRPC3, and TRPM7 using normal biopsy without microcalcifications (controls and infiltrating ductal carcinoma with microcalcifications was evaluated.Results: Data on 138 women were analyzed. Seventy percent of women had a BI-RADS score (1–3 corresponding to benign disease. Seventy-six percent of women with a BI-RADS score (4 or 5 were diagnosed with breast cancer, 56% were cancers in situ, and 93% were infiltrating ductal carcinomas. No difference in the distribution of corrected serum Ca2+ levels between BI-RADS scores (1–3 and BI-RADS scores (4–5 (P = 0.82 was observed. Serum Ca2+ levels were similar in women without cancer and women diagnosed with breast cancer (P = 0.94. However, the expression of TRPM7 and TRPC1, but not TRPC3, Ca2+ channels were increased in infiltrating ductal carcinoma samples with microcalcifications when compared with age-matched controls without calcification or cancer.Conclusion: We observed an increase in the expression of TRPM7 and TRPC1 Ca2+ channels in infiltrating ductal carcinoma samples with microcalcifications, whereas no change in serum Ca2+ levels was observed. Together these data suggest that increased expression of these channels might

  20. Change of teicoplanin loading dose requirement for incremental increases of systemic inflammatory response syndrome score in the setting of sepsis.

    Science.gov (United States)

    Nakano, Takafumi; Nakamura, Yoshihiko; Takata, Tohru; Irie, Keiichi; Sano, Kazunori; Imakyure, Osamu; Mishima, Kenichi; Futagami, Koujiro

    2016-08-01

    Background Target trough concentrations are recommended for teicoplanin (TEIC) to minimize its adverse effects and to maximize efficacy in sepsis caused by grampositive cocci, including methicillin-resistant Staphylococcus aureus infection. However, optimal doses to attain proper trough values in patients with sepsis have not yet been well established for TEIC. Objective This study investigated whether the systemic inflammatory response syndrome (SIRS) score could predict the pharmacokinetics of TEIC in patients with sepsis. Setting This study was conducted at Fukuoka University Hospital in Japan. Methods We retrospectively reviewed the records of patients using TEIC between April 2012 and March 2015. SIRS positive was defined as infection with a SIRS score ≥2. Estimates of pharmacokinetic parameters were calculated using a Bayesian method. Creatinine clearance rates were estimated by the Cockcroft-Gault formula (eCcr). Main outcome measure Change of TEIC loading dose requirement for incremental increases of SIRS score. Results In total, 133 patients were enrolled: 50 non-SIRS patients and 83 patients with SIRS. The TEIC plasma trough concentration was significantly lower in SIRS than non-SIRS patients (15.7 ± 7.1 vs. 20.1 ± 8.6 μg/mL; P < 0.01), although there was no significant difference in the loading dose administered. Moreover, SIRS scores were increasingly predictive of eCcr and TEIC clearance in a stepwise manner. To achieve the target trough concentration (15-30 μg/mL), the optimal doses required in non-SIRS versus SIRS patients were 12-24 versus 18-30 mg/kg/day, respectively, during the first 48 h. Conclusions These findings suggest that the pharmacokinetics of TEIC are altered in SIRS patients, who required higher doses than non-SIRS patients to achieve the target trough concentration. We suggest that the SIRS score can become a new modality to determine the initial TEIC loading dose. PMID:27125378

  1. A systematic literature review analysis of ultrasound joint count and scoring systems to assess synovitis in rheumatoid arthritis according to the OMERACT filter

    DEFF Research Database (Denmark)

    Mandl, Peter; Naredo, Esperanza; Wakefield, Richard J;

    2011-01-01

    The OMERACT Ultrasound Task Force is currently developing a global synovitis score (GLOSS) with the objective of feasibly measuring global disease activity in patients with rheumatoid arthritis (RA). In order to determine the minimal number of joints to be included in such a scoring system...

  2. The High Performance of Dutch and Flemish 15-Year-Old Native Pupils: Explaining Country Differences in Math Scores between Highly Stratified Educational Systems

    Science.gov (United States)

    Prokic-Breuer, Tijana; Dronkers, Jaap

    2012-01-01

    This paper aims to explain the high scores of 15-year-old native pupils in The Netherlands and Flanders by comparing them with the scores of pupils in countries with the same highly stratified educational system: Wallonia, the German "Lander," the Swiss German cantons, and Austria. We use the data from the Programme for International Pupil…

  3. Diagnosis of pulmonary tuberculosis by score system in children and adolescents: a trial in a reference center in Bahia, Brazil

    Directory of Open Access Journals (Sweden)

    Clemax Couto Sant'Anna

    2004-08-01

    Full Text Available Since 2002, the Brazilian Ministry of Health has recommended a score system for tuberculosis diagnosis of children and adolescents that does not need bacteriological positivity, because most cases in this age group have few bacteria. An observational, transversal study was carried out at the outpatient health care service of the reference medical service in Salvador, Bahia, including 164 patients with pulmonary tuberculosis, with ages ranging between 1 and 15 years of age, who were treated from 1990 to 2001. The gold standard used to establish the diagnosis was clinical, radiological, epidemiological and based on follow-up data. The score system for diagnosis purposes was tested retrospectively. The median age and the average age of the 164 patients were 6 and 6.62 years (SD ± 4.33, respectively. About 65% of the sample reported a history of close contact with a tuberculous adult. The BCG vaccine coverage was 70.7% (116/164. It was found that 26% (43/164 of the patients had severe malnutrition. Out of this group, 26/43 (60.47% were < 5mm reactive to the tuberculin test. On the other hand, out of the 91 patients with tuberculin test < 5mm, 29% (26/ 91 had severe malnutrition. The use of the score gave the following distribution: a TB very likely in 81.7% (134/164 of the patients; b possible TB in 15.9% (26/164 and TB unlikely in 2.4% (4/164. Among patients who had been vaccinated more than 2 years before, there was a 9 times higher risk of finding a tuberculin test above 10 mm in individuals with probable TB in comparison with the patients with possible or unlikely TB.

  4. APACHE IV is superior to MELD scoring system in predicting prognosis in patients after orthotopic liver transplantation.

    Science.gov (United States)

    Hu, Yueyun; Zhang, Xianling; Liu, Yuan; Yan, Jun; Li, Tiehua; Hu, Ailing

    2013-01-01

    This study aims to compare the efficiency of APACHE IV with that of MELD scoring system for prediction of the risk of mortality risk after orthotopic liver transplantation (OLT). A retrospective cohort study was performed based on a total of 195 patients admitted to the ICU after orthotopic liver transplantation (OLT) between February 2006 and July 2009 in Guangzhou, China. APACHE IV and MELD scoring systems were used to predict the postoperative mortality after OLT. The area under the receiver operating characteristic curve (AUC) and the Hosmer-Lemeshow C statistic were used to assess the discrimination and calibration of APACHE IV and MELD, respectively. Twenty-seven patients died during hospitalization with a mortality rate of 13.8%. The mean scores of APACHE IV and MELD were 42.32 ± 21.95 and 18.09 ± 10.55, respectively, and APACHE IV showed better discrimination than MELD; the areas under the receiver operating characteristic curve for APACHE IV and MELD were 0.937 and 0.694 (P APACHE IV was relatively high. Both models were well-calibrated (The Hosmer-Lemeshow C statistics were 1.568 and 6.818 for APACHE IV and MELD, resp.; P > 0.05 for both). The respective Youden indexes of APACHE IV, MELD, and combination of APACHE IV with MELD were 0.763, 0.430, and 0.545. The prognostic value of APACHE IV is high but still underestimates the overall hospital mortality, while the prognostic value of MELD is poor. The function of the APACHE IV is, thus, better than that of the MELD.

  5. Olympic Scoring of English Compositions

    Science.gov (United States)

    Follman, John; Panther, Edward

    1974-01-01

    Examines empirically the efficacy of utilizing Olympic diving and gymnastic scoring systems for grading graduate students' English compositions. Results indicated that such scoring rules do not produce ratings different in reliability or in level from conventional letter grades. (ED)

  6. The accuracy of a clinical parameters-based scoring system to predict spontaneous intracranial hemorrhage in children under one year old

    Directory of Open Access Journals (Sweden)

    Harris Alfan

    2015-05-01

    Full Text Available Background Previous studies show that most children aged less than 1 year had intracranial hemorrhage without any history of trauma. The sign and symptoms of spontaneous intracranial hemorrhage (SIH in children varies. To minimize morbidity and mortality, early detection and accurate diagnosis are required. Head CT scans area widely used for diagnosing SIH. Unfortunately, not all health facilities in Indonesia have CT scans. Objective To determine the accuracy of a clinical parameters-based scoring system in predicting spontaneous intracranial hemorrhage (SIH in children under one year old. Methods This diagnostic study included children aged under one year who were admitted to Mohammad Hoesin Hospital, Palembang. Patients who showed any signs of increased intracranial pressure were recruited. Data were collected from medical records from January 2007 to September 2013. Through the use of logistic regression analysis, clinical parameters showing significant relationships with computerized tomography (CT-scan confirmed SIH were selected as predictors. Each predictor was given a score based on an adjusted ratio. The cut-off point of the total scores from all patients was determined using a receiver operating curve (ROC analysis. The accuracy of the total scores was calculated using a 2x2 validity test. Results Of the 186 children included in this study, 98 (52.7% had SIH and 93 (94.8% were under 3 month-old. The predictors for SIH used included age (>3 months: score 0; 1-3 months: score 3, gender (female: score 0; male: score 1, pallor (no: score 0; yes: score 1, bulging fontanel (no: score 0; yes: score 1, pupil (isocoria: score 0; anisocoria: score 2 and history of shaken baby (no: score 0; yes: score 3. The ROC analysis showed that the area under the curve (AUC was 95.3% with a cut-off point of 4.5, had a sensitivity of 88.7% and a specificity of 93.1% Conclusion This scoring system based on clinical parameters hadgood accuracy for predicting

  7. Injury to the lung from cancer therapy: Clinical syndromes, measurable endpoints, and potential scoring systems

    International Nuclear Information System (INIS)

    Toxicity of the respiratory system is a common side effect and complication of anticancer therapy that can result in significant morbidity. The range of respiratory compromise can extend from acute lethal events to degrees of chronic pulmonary decompensation, manifesting years after the initial cancer therapy. This review examines the anatomic-histologic background of the lung and the normal functional anatomic unit. The pathophysiology of radiation and chemotherapy induced lung injury is discussed as well as the associated clinical syndromes. Radiation tolerance doses and volumes are assessed in addition to chemotherapy tolerance and risk factors and radiation-chemotherapy interactions. There are a variety of measurable endpoints for detection and screening. Because of the wide range of available quantitative tests, it would seem that the measurement of impaired lung function is possible. The development of staging systems for acute and late toxicity is discussed and a new staging system for Late Effects in Normal Tissues (LENT) is proposed

  8. Risk Factors and Scoring System for Predicting Bacterial Resistance to Cefepime as Used Empirically in Haematology Wards

    Directory of Open Access Journals (Sweden)

    Hicham El Maaroufi

    2015-01-01

    Full Text Available Objectives. Bacterial resistance is of growing concern in haematology wards. As the inappropriate administration of empirical antibacterial may alter survival, we studied risk factors for resistance to our usual empirical first-line antibacterial therapy, cefepime. Methods. We retrospectively studied 103 first episodes of bacteraemia recorded in our haematology department over 2.5 years. Risk factors for cefepime-resistance were identified by multivariate logistic regression with backward selection (P<0.05. A scoring system for predicting cefepime-resistance was built on independent factor, with an internal validation by the bootstrap resampling technique. Results. 38 (37% episodes were due to Gram-negative bacteria. Fifty (49% were due to bacteria resistant to cefepime. Cefepime resistance was significantly associated with a decreased survival at day 30 (P<0.05. Three risk factors were independently associated with cefepime-resistance: acute lymphoblastic leukaemia; ≥18 days since hospital admission; and receipt of any β-lactam in the last month. Patients with ≥2 of these risk factors had a probability of 86% (CI 95%, 25 to 100% to carry a cefepime-resistant strain. Conclusion. Using our scoring system should reduce the indication of very broad antibacterial regimens in the empirical, first-line treatment of febrile hematology patients in more than 80% of the cases.

  9. Behavioural linear standardized scoring system of the Lidia cattle breed by testing in herd: estimation of genetic parameters.

    Science.gov (United States)

    Pelayo, R; Solé, M; Sánchez, M J; Molina, A; Valera, M

    2016-10-01

    Docility is very important for cattle production, and many behavioural tests to measure this trait have been developed. However, very few objective behavioural tests to measure the opposite approach 'aggressive behaviour' have been described. Therefore, the aim of this work was to validate in the Lidia cattle breed a behavioural linear standardized scoring system that measure the aggressiveness and enable genetic analysis of behavioural traits expressing fearless and fighting ability. Reproducibility and repeatability measures were calculated for the 12 linear traits of this scoring system to assess its accuracy, and ranged from 85.3 and 94.2%, and from 66.7 to 97.9%, respectively. Genetic parameters were estimated using an animal model with a Bayesian approach. A total of 1202 behavioural records were used. The pedigree matrix contained 5001 individuals. Heritability values (with standard deviations) ranged between 0.13 (0.04) (Falls of the bull) and 0.41 (0.08) (Speed of approach to horse). Genetic correlations varied from 0.01 (0.07) to 0.90 (0.13). Finally, an exploratory factor analysis using the genetic correlation matrix was calculated. Three main factors were retained to describe the traditional genetic indexes aggressiveness, strength and mobility.

  10. A cross-sectional study of the Birmingham Vasculitis Activity Score version 3 in systemic vasculitis.

    LENUS (Irish Health Repository)

    Suppiah, Ravi

    2011-05-01

    Assessment of disease activity in vasculitis can be achieved using the BVAS, a clinical checklist of relevant symptoms, signs and features of active disease. The aim of this study was to revalidate the BVAS version 3 (BVAS v. 3) in a cohort of patients with systemic vasculitis.

  11. Using Projects Scoring Rubrics to Assess Student Learning in an Information Systems Program

    Science.gov (United States)

    Petkov, Doncho; Petkova, Olga; D'Onofrio, Marianne; Jarmoszko, A. T.

    2008-01-01

    This paper is about using projects for assessment of student learning in different courses of an Information Systems (IS) program. An overview of the role of educational projects in student learning is presented. The various aspects of defining standardized rubrics across an IS program are discussed. A methodology for the use of such rubrics in…

  12. The predictive validity of grade point average scores in a partial lottery medical school admission system

    NARCIS (Netherlands)

    Cohen-Schotanus, Janke; Muijtjens, Arno M. M.; Reinders, Jan J.; Agsteribbe, Jessica; van Rossum, Herman J. M.; van der Vleuten, Cees P. M.

    2006-01-01

    PURPOSE To ascertain whether the grade point average (GPA) of school-leaving examinations is related to study success, career development and scientific performance. The problem of restriction of range was expected to be partially reduced due to the use of a national lottery system weighted in favou

  13. Scoring system for the selection of high-risk patients in the intensive care unit

    NARCIS (Netherlands)

    Iapichino, G; Mistraletti, G; Corbella, D; Bassi, G; Borotto, E; Miranda, DR; Morabito, A

    2006-01-01

    Objective. Patients admitted to the intensive care unit greatly differ in severity and intensity of care. We devised a system for selecting high-risk patients that reduces bias by excluding low-risk patients and patients with an early death irrespective of the treatment. Design: A posteriori analysi

  14. Comparison of two cleansing pastes for the removal of biofilm from dentures and palatal lesions in patients with atrophic chronic candidiasis.

    Science.gov (United States)

    Andrucioli, Marcela Cristina Damião; de Macedo, Leandro Dorigan; Panzeri, Heitor; Lara, Elza Helena Guimarães; Paranhos, Helena de Freitas Oliveira

    2004-01-01

    The efficacy of 2 oral hygiene products, an experimental toothpaste specific for complete denture cleansing and a regular standard toothpaste, was compared in terms of denture biofilm removal and cure of palatal lesions in patients with atrophic chronic candidiasis. The degree of correlation between presence of biofilm and mucosa erythema was also evaluated. Twenty-four complete denture wearers (45-80 years old) were divided into 2 groups: experimental paste and standard toothpaste (Sorriso-Kolynos, Brazil). Both groups received soft toothbrushes. The internal surfaces of upper dentures were stained using 1% sodium fluorescein and photographed at a 45 masculine angle at 0, 15, 30 and 60 days. The slides were scanned and the areas of interest (denture total area and biofilm area) were measured (Image Tool software). The degree of erythema was evaluated on slides according to the Prosthesis Tissue Index. There was a significant reduction (1%) in the degree of biofilm (ANOVA/Tukey) between the two initial visits (0 and 15 days) and the two final visits (30 and 60 days), and in the average erythema scores (Kruskal-Wallis) between 0 and 60 days, in both groups. The Mann-Whitney test showed a significant difference (1%) between pastes in terms of biofilm degree, but no difference was found for the erythema score. Correlation values between biofilm and erythema degree were 0.3801 (experimental paste) and (0.3678 (standard toothpaste). We may therefore conclude that the experimental product was efficient for the removal of denture plaque biofilm.

  15. A chest radiograph scoring system in patients with severe acute respiratory infection: a validation study

    OpenAIRE

    Taylor, Emma; Haven, Kathryn; Reed, Peter; Bissielo, Ange; Harvey, Dave; McArthur, Colin; Bringans, Cameron; Freundlich, Simone; Ingram, R. Joan H.; Perry, David; Wilson, Francessa; Milne, David; Modahl, Lucy; Huang, Q. Sue; Gross, Diane

    2015-01-01

    Background The term severe acute respiratory infection (SARI) encompasses a heterogeneous group of respiratory illnesses. Grading the severity of SARI is currently reliant on indirect disease severity measures such as respiratory and heart rate, and the need for oxygen or intensive care. With the lungs being the primary organ system involved in SARI, chest radiographs (CXRs) are potentially useful for describing disease severity. Our objective was to develop and validate a SARI CXR severity s...

  16. A Reference Architecture and Score Representation for Popular Music Human-Computer Music Performance Systems

    OpenAIRE

    Gold, N. E.; Dannenberg, R. B.

    2011-01-01

    Popular music (characterized by improvised instrumental parts, beat and measure-level organization, and steady tempo) poses challenges for human-computer music performance (HCMP). Pieces of music are typically rearrangeable on-the-fly and involve a high degree of variation from ensemble to ensemble, and even between rehearsal and performance. Computer systems aiming to participate in such ensembles must therefore cope with a dynamic high-level structure in addition to the more traditional pro...

  17. Systemic Inflammatory Response Syndrome and MELD Score in Hospital Outcome of Patients with Liver Cirrhosis

    OpenAIRE

    Behroozian, Ramin; Bayazidchi, Mehrdad; Rasooli, Javad

    2012-01-01

    BACKGROUND The evidence saying that the rate of Systemic Inflammatory Response Syndrome (SIRS) is high in patients with advanced cirrhosis and portal hypertension, this could have negative outcome on patients prognosis. METHODS This prospective study included 109 cirrhotic patients who were admitted to Imam Khomeini Hospital, affiliated with Orumieh University of Medical Sciences, during 2011-2012. The presence of SIRS and the model for end stage liver disease (MELD) were assessed on admissio...

  18. Injury to the lung from cancer therapy: Clinical syndromes, measurable endpoints, and potential scoring systems

    Energy Technology Data Exchange (ETDEWEB)

    McDonald, S.; Rubin, P. [Univ. of Rochester Cancer Center, NY (United States); Phillips, T.L. [Univ. of California, San Francisco, CA (United States)] [and other

    1995-03-30

    Toxicity of the respiratory system is a common side effect and complication of anticancer therapy that can result in significant morbidity. The range of respiratory compromise can extend from acute lethal events to degrees of chronic pulmonary decompensation, manifesting years after the initial cancer therapy. This review examines the anatomic-histologic background of the lung and the normal functional anatomic unit. The pathophysiology of radiation and chemotherapy induced lung injury is discussed as well as the associated clinical syndromes. Radiation tolerance doses and volumes are assessed in addition to chemotherapy tolerance and risk factors and radiation-chemotherapy interactions. There are a variety of measurable endpoints for detection and screening. Because of the wide range of available quantitative tests, it would seem that the measurement of impaired lung function is possible. The development of staging systems for acute and late toxicity is discussed an a new staging system for Late Effects in Normal Tissues :(LENT) is proposed. 115 refs., 2 figs., 9 tabs.

  19. ECG scores for a triage of patients with acute myocardial infarction transported by the emergency medical system.

    Science.gov (United States)

    Zalenski, R J; Grzybowski, M; Ross, M A; Blaustein, N; Bock, B

    2000-01-01

    Prehospital triage of cardiac patients for bypass from community hospitals to cardiac centers may improve survival. This article determines if electrocardiogram (ECG)-based scoring triage methods (Aldrich MI scoring, QRS distortion, and the TIMI classification) and location of infarct (via 12 lead ECG) are associated with mortality before and after adjusting for age, sex, and race. It is a retrospective study of 291 AMI adult patients transported by ambulance to community hospitals or cardiac centers. Patients with an ED chief complaint of chest pain or dyspnea, presence of MI as defined by ECG findings of 0.1 mV of ST segment elevation in two leads or positive CPK-MB were eligible for the study. The primary outcome variable was 2-year mortality as determined with a metropolitan Detroit tri-county death index. Logistic regression was used to calculate the unadjusted and adjusted odds ratios (with 95% CIs) of the predictor variables with mortality. Of the initial population selected for the study (n = 291), 229 patients were eligible for the analysis. The mean age was 66 years (SD of 14.4) with 63.8% being male and 54% being white. The overall mortality point estimate was 21.3% (95% CI of 15.2 to 27.3%). Aldrich scores and QRS distortion (yes/no) were not associated with mortality. Patients classified as a "high risk" for AMI per TIMI status were almost 3 times more likely to die than those at "low risk" and reached borderline statistical significance (P = .06) after adjusting for the covariates. Having an anterior infarct, as opposed to an inferior infarct, was significantly associated with death before and after adjusting for the covariates (Unadjusted OR = 2.6, Adjusted OR = 2.8). Properly training emergency medical system professionals in this area may prove useful for identifying higher risk AMI patients in the prehospital setting. PMID:11265729

  20. Development, Methodology and Potential of the New Universal Visual Scoring System (UniViSS for Caries Detection and Diagnosis

    Directory of Open Access Journals (Sweden)

    Thomas Oehme

    2009-09-01

    Full Text Available Given the limitations of adjunct caries detection and diagnostic tools, e.g., imperfect validity and reproducibility, as well as the difficulties in controlling all possible confounding factors, the need for an objective visual caries detection and diagnosis system has become evident. Our work has therefore aimed at systematizing caries lesions with the Universal Visual Scoring System (UniViSS for occlusal and smooth surface lesions, which can be used for primary and permanent teeth, as well as under clinical, epidemiological, public health and laboratory conditions. Besides the description of the development and methodology of UniViSS, it is shown that UniViSS allows an accurate and reproducible classification of caries lesions on occlusal surfaces.

  1. Development of an image based system to objectively score the severity of phoriasis

    DEFF Research Database (Denmark)

    Gomez, David Delgado

    2005-01-01

    The objective of this thesis is to provide a possible solution to one of the current problems in dermatology: the lack of suitable methods to objectively evaluate the severity of dermatological lesions. An image based system is developed with the goal of automatically obtaining summarization values...... that characterize the lesion and help to track the evolution of the disease. The thesis starts by analyzing an accurate type of equipment with which collect dermatological images. Later, a method to segment the different areas embedded in dermatological lesions is developed. Results of the segmentation task...... will be used to obtain values that characterize the lesion. The last part of the thesis considers the possibility of including more bands in the analysis in order to increase the accuracy of the proposed method....

  2. A SCORING SYSTEM TO IMPROVE DECISION MAKING AND OUTCOMES IN THE ADAPTATION OF RECENTLY CAPTURED WHITE RHINOCEROSES (CERATOTHERIUM SIMUM) TO CAPTIVITY.

    Science.gov (United States)

    Miller, Michele; Kruger, Milandie; Kruger, Marius; Olea-Popelka, Francisco; Buss, Peter

    2016-04-01

    Ninety-four subadult and adult white rhinoceroses (Ceratotherium simum) were captured between February and October, 2009-11, in Kruger National Park and placed in holding bomas prior to translocation to other locations within South Africa. A simple three-category system was developed based on appetite, fecal consistency/volume, and behavior to assess adaptation to bomas. Individual animal and group daily median scores were used to determine trends and when rhinoceroses had successfully adapted to the boma. Seventeen rhinoceroses did not adapt to boma confinement, and 16 were released (1 mortality). No differences in boma scores were observed between rhinoceroses that adapted and those that did not, until day 8, when the first significant differences were observed (adapted score=13 versus nonadapted score=10). The time to reach a boma score determined as successful adaptation (median 19 d) matched subjective observations, which was approximately 3 wk for most rhinoceroses. Unsuccessful adaptation was indicated by an individual boma score of less than 15, typically during the first 2 wk, or a declining trend in scores within the first 7-14 d. This scoring system can be used for most locations and could also be easily adapted to other areas in which rhinoceroses are held in captivity. This tool also provides important information for assessing welfare in newly captured rhinoceroses. PMID:26845302

  3. A SCORING SYSTEM TO IMPROVE DECISION MAKING AND OUTCOMES IN THE ADAPTATION OF RECENTLY CAPTURED WHITE RHINOCEROSES (CERATOTHERIUM SIMUM) TO CAPTIVITY.

    Science.gov (United States)

    Miller, Michele; Kruger, Milandie; Kruger, Marius; Olea-Popelka, Francisco; Buss, Peter

    2016-04-01

    Ninety-four subadult and adult white rhinoceroses (Ceratotherium simum) were captured between February and October, 2009-11, in Kruger National Park and placed in holding bomas prior to translocation to other locations within South Africa. A simple three-category system was developed based on appetite, fecal consistency/volume, and behavior to assess adaptation to bomas. Individual animal and group daily median scores were used to determine trends and when rhinoceroses had successfully adapted to the boma. Seventeen rhinoceroses did not adapt to boma confinement, and 16 were released (1 mortality). No differences in boma scores were observed between rhinoceroses that adapted and those that did not, until day 8, when the first significant differences were observed (adapted score=13 versus nonadapted score=10). The time to reach a boma score determined as successful adaptation (median 19 d) matched subjective observations, which was approximately 3 wk for most rhinoceroses. Unsuccessful adaptation was indicated by an individual boma score of less than 15, typically during the first 2 wk, or a declining trend in scores within the first 7-14 d. This scoring system can be used for most locations and could also be easily adapted to other areas in which rhinoceroses are held in captivity. This tool also provides important information for assessing welfare in newly captured rhinoceroses.

  4. 21 CFR 701.20 - Detergent substances, other than soap, intended for use in cleansing the body.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Detergent substances, other than soap, intended... Ingredients § 701.20 Detergent substances, other than soap, intended for use in cleansing the body. (a) In its definition of the term cosmetic, the Federal Food, Drug, and Cosmetic Act specifically excludes soap....

  5. Melanoma maligno cutâneo: sistema de pontos (scoring system para auxílio no diagnóstico histopatológico Cutaneous malignant melanoma: scoring system to assist in the histopathologic diagnosis

    Directory of Open Access Journals (Sweden)

    Luiz Alberto Veronese

    2006-10-01

    Full Text Available INTRODUÇÃO: O diagnóstico histopatológico de algumas lesões melanocíticas pode ser muito difícil, mesmo para especialistas, mas há casos em que a dificuldade surge pela inadequada e subjetiva aplicação dos critérios diagnósticos. OBJETIVO: O objetivo deste estudo é desenvolver um método de aplicação sistemática desses critérios, atribuindo valores para os mais importantes. MATERIAL E MÉTODOS: Selecionaram-se os critérios mais relevantes para o diagnóstico de melanoma, atribuindo valores de 1 a 5 de acordo com sua importância. Foram escolhidos 101 casos de melanomas de tipo extensivo-superficial com menos de 2mm de espessura para análise comparativa com 33 lesões melanocíticas benignas (13 nevos de Spitz, seis de Reed, seis displásicos, três congênitos, três adquiridos, um combinado e um recorrente. RESULTADOS: A soma dos valores dados aos critérios (score apresentou diferença significativa entre lesões malignas e benignas, mostrando que esse método pode ser útil ao patologista cirúrgico generalista em sua rotina diária. CONCLUSÃO: A aplicação objetiva e sistemática dos critérios histopatológicos pelo sistema de pontos (scoring system pode ajudar o diagnóstico diferencial entre maligno e benigno em muitas lesões, porém não tendo o efeito desejado nas lesões melanocíticas de comportamento biológico indeterminado.INTRODUCTION: The histopathological diagnosis of melanocytic lesions may be very difficult, even by experts within the field. The challenge can come from inaccurate and/or subjective application of the diagnosis criteria. AIM: The goal of this study was to develop a method of systematic application of histopathological criteria as a result of the most relevant microscopic characteristics. MATERIAL AND METHODS: The most important criteria to diagnosing melanoma on histopathological bases were selected and given points ranging from 1 to 5 according to their relevance to the melanoma diagnosis

  6. Deep learning for electronic cleansing in dual-energy CT colonography

    Science.gov (United States)

    Tachibana, Rie; Näppi, Janne J.; Hironakaa, Toru; Kim, Se Hyung; Yoshida, Hiroyuki

    2016-03-01

    The purpose of this study was to develop a novel deep-learning-based electronic cleansing (EC) method for dual-energy CT colonography (DE-CTC). In this method, an ensemble of deep convolutional neural networks (DCNNs) is used to classify each voxel of DE-CTC image volumes into one of five multi-material (MUMA) classes: luminal air, soft tissue, tagged fecal material, or a partial-volume boundary between air and tagging or that of soft tissue and tagging. Each DCNN acts as a voxel classifier. At each voxel, a region-of-interest (ROI) centered at the voxel is extracted. After mapping the pixels of the ROI to the input layer of a DCNN, a series of convolutional and max-pooling layers is used to extract features with increasing levels of abstraction. The output layer produces the probabilities at which the input voxel belongs to each of the five MUMA classes. To develop an ensemble of DCNNs, we trained multiple DCNNs based on multi-spectral image volumes derived from the DE-CTC images, including material decomposition images and virtual monochromatic images. The outputs of these DCNNs were then combined by means of a meta-classifier for precise classification of the voxels. Finally, the electronically cleansed CTC images were generated by removing regions that were classified as other than soft tissue, followed by colon surface reconstruction. Preliminary results based on 184,320 images sampled from 30 clinical CTC cases showed a higher accuracy in labeling these classes than that of our previous machine-learning methods, indicating that deep-learning-based multi-spectral EC can accurately remove residual fecal materials from CTC images without generating major EC artifacts.

  7. Evaluation of intestinal phosphate binding to improve the safety profile of oral sodium phosphate bowel cleansing.

    Directory of Open Access Journals (Sweden)

    Stef Robijn

    Full Text Available Prior to colonoscopy, bowel cleansing is performed for which frequently oral sodium phosphate (OSP is used. OSP results in significant hyperphosphatemia and cases of acute kidney injury (AKI referred to as acute phosphate nephropathy (APN; characterized by nephrocalcinosis are reported after OSP use, which led to a US-FDA warning. To improve the safety profile of OSP, it was evaluated whether the side-effects of OSP could be prevented with intestinal phosphate binders. Hereto a Wistar rat model of APN was developed. OSP administration (2 times 1.2 g phosphate by gavage with a 12h time interval induced bowel cleansing (severe diarrhea and significant hyperphosphatemia (21.79 ± 5.07 mg/dl 6h after the second OSP dose versus 8.44 ± 0.97 mg/dl at baseline. Concomitantly, serum PTH levels increased fivefold and FGF-23 levels showed a threefold increase, while serum calcium levels significantly decreased from 11.29 ± 0.53 mg/dl at baseline to 8.68 ± 0.79 mg/dl after OSP. OSP administration induced weaker NaPi-2a staining along the apical proximal tubular membrane. APN was induced: serum creatinine increased (1.5 times baseline and nephrocalcinosis developed (increased renal calcium and phosphate content and calcium phosphate deposits on Von Kossa stained kidney sections. Intestinal phosphate binding (lanthanum carbonate or aluminum hydroxide was not able to attenuate the OSP induced side-effects. In conclusion, a clinically relevant rat model of APN was developed. Animals showed increased serum phosphate levels similar to those reported in humans and developed APN. No evidence was found for an improved safety profile of OSP by using intestinal phosphate binders.

  8. A new, preoperative, MRI-based scoring system for diagnosing malignant axillary lymph nodes in women evaluated for breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    He, Ni, E-mail: 61684754@qq.com [Department of Medical Imaging and Interventional Radiology, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou 510060 (China); Xie, Chuanmiao, E-mail: xiechm@sysucc.org.cn [Department of Medical Imaging and Interventional Radiology, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou 510060 (China); Wei, Weidong, E-mail: weiwd@sysucc.org.cn [Department of Breast, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou 510060 (China); Pan, Changchuan, E-mail: 1253719670@qq.com [Department of Medical Imaging and Interventional Radiology, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou 510060 (China); Wang, Wenyan, E-mail: 7344362@qq.com [College of Electronic Engineering, Guangxi Normal University, Guilin 541004 (China); Lv, Ning, E-mail: 409109980@qq.com [Department of Breast, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou 510060 (China); Wu, Peihong, E-mail: mit@caca.sina.net [Department of Medical Imaging and Interventional Radiology, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou 510060 (China)

    2012-10-15

    Objective: Malignant axillary lymph nodes are an important predictor for breast cancer recurrence, but invasive dissection or biopsy is required for the diagnosis. We determined whether and how malignant nodes could be diagnosed preoperatively with magnetic resonance (MR) imaging. Materials and methods: We obtained MR images of all women evaluated for breast cancer at the Sun Yat-Sen University Cancer Center in 2010 and correlated the image characteristics of each axillary node with the pathologic diagnosis of the same node. Results: We analyzed 251 nodes (117 benign; 134 malignant) from 136 women (mean age, 44 years; range, 20–67). Mean diameter of the nodes was 18 mm (range, 5–58 mm). With pathologic diagnosis as the reference standard, MRI-based interpretations were 66.4% sensitive, 94% specific, and 79% accurate. Diameter, pathologic type, apparent diffusion coefficient value (ADC, b = 500 and 800), time-intensity curve (TIC) type of breast tumors correlated with node metastasis; ADC value (b = 500 and 800), TIC type, early enhancement rate, long-axis, short-axis, shape, margin and the location of nodes correlated with node metastasis (P < 0.001 for all). Tumor immunohistochemistry results for estrogen receptors, progesterone receptors, c-erbB-2, vascular endothelial growth factor, and Ki67 were not. An MRI-based lymph node scoring system based on these correlations had a specificity of 91%, a sensitivity of 93%, and an area under the ROC curve of 0.95 (P < 0.001). Conclusion: Metastatic axillary lymph nodes can be accurately diagnosed by MR in women with early breast cancer preoperatively and non-invasively. The scoring system appears to be superior to current methods.

  9. Deceleration in maturation of bone during adolescent age in achondroplasia - a retrospective study using RUS scoring system

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Suk-Ha [Konkuk University Hospital, Department of Orthopedics, Seoul (Korea); Modi, Hitesh N.; Suh, Seung Woo [Korea University Guro Hospital, Scoliosis Research Institute, Department of Orthopedics, Seoul (Korea); Song, Hae-Ryong; Hazra, Sunit; Modi, Chetna [Korea University Guro Hospital, Rare Disease Institute, Department of Orthopedics, Seoul (Korea)

    2009-02-15

    Knowledge of bone age in achondroplasia is required for the prediction of adult height, timings of limb lengthening, and epiphysiodesis procedures. The purpose of this investigation was to determine the differences in skeletal age in achondroplasia and a control population with the Tanner-Whitehouse 3 method using the RUS score and to determine the right age for the interventional procedure for limb lengthening procedure or deformity correction in these patients. Left hand radiographs of 34 patients (age range, 5-18 years) with achondroplasia were evaluated for skeletal age using the RUS scoring system, which were compared with the left hand radiographs of 41 patients (age range, 5-18 years) without achondroplasia measuring skeletal age. The difference in chronological age and RUS bone age were evaluated statistically according to gender and age group. In the achondroplasia group, chronological age were 10.5{+-}4.3 years for males and 10.1{+-}3.6 years for females and RUS bone age were 9.2{+-}4.0 years for males and 8.9{+-}3.4 years for females, which showed statistically significantly difference (males p=0.0003 and females p < 0.0001), while in the control group, chronological age were 11.1{+-}2.9 years for males and 10.7{+-}3.4 years for females and RUS bone age were 11.2{+-}3.4 years for males and 10.7{+-}3.3 years for females, which did not show statistically significantly difference (males p=0.54 and females p=0.76). Our finding suggested a delay of 1.4 years for males and 1.2 years for females in the maturation of bone in achondroplasia patients. Difference between chronological age and RUS bone age was 0.9{+-}1.1 for <10 years and 1.6{+-}0.9 for >10 years in the study group, while 0.1{+-}1.1 for <10 years and -0.2 {+-} 0.6 for >10 years in the control group, which also showed >statistically significant difference (<10 years p=0.04 and >10 years p<0.0001). These differences indicate that there was a delay in the maturation of bones by 1 year in the group <10

  10. Multicenter retrospective evaluation of the validity of the Thoracolumbar Injury Classification and Severity Score system in children.

    Science.gov (United States)

    Sellin, Jonathan N; Steele, William J; Simpson, Lauren; Huff, Wei X; Lane, Brandon C; Chern, Joshua J; Fulkerson, Daniel H; Sayama, Christina M; Jea, Andrew

    2016-08-01

    OBJECTIVE The Thoracolumbar Injury Classification and Severity Score (TLICS) system was developed to streamline injury assessment and guide surgical decision making. To the best of the authors' knowledge, external validation in the pediatric age group has not been undertaken prior to this report. METHODS This study evaluated the use of the TLICS in a large retrospective series of children and adolescents treated at 4 pediatric medical centers (Texas Children's Hospital, Children's Healthcare of Atlanta, Riley Children's Hospital, and Doernbecher Children's Hospital). A total of 147 patients treated for traumatic thoracic or lumbar spine trauma between February 1, 2002, and September 1, 2015, were included in this study. Clinical and radiographic data were evaluated. Injuries were classified using American Spinal Injury Association (ASIA) status, Denis classification, and TLICS. RESULTS A total of 102 patients (69%) were treated conservatively, and 45 patients (31%) were treated surgically. All patients but one in the conservative group were classified as ASIA E. In this group, 86/102 patients (84%) had Denis type compression injuries. The TLICS in the conservative group ranged from 1 to 10 (mean 1.6). Overall, 93% of patients matched TLICS conservative treatment recommendations (score ≤ 3). No patients crossed over to the surgical group in delayed fashion. In the surgical group, 26/45 (58%) were ASIA E, whereas 19/45 (42%) had neurological deficits (ASIA A, B, C, or D). One of 45 (2%) patients was classified with Denis type compression injuries; 25/45 (56%) were classified with Denis type burst injuries; 14/45 (31%) were classified with Denis type seat belt injuries; and 5/45 (11%) were classified with Denis type fracture-dislocation injuries. The TLICS ranged from 2 to 10 (mean 6.4). Eighty-two percent of patients matched TLICS surgical treatment recommendations (score ≥ 5). No patients crossed over to the conservative management group. Eight patients (8

  11. HAEMATOLOGICAL SCORING SYSTEM (HSS IN EARLY DIAGNOSIS OF NEONATAL SEPSIS: A STUDY FROM TERTIARY CARE HOSPITAL FROM NORTH EAST INDIA

    Directory of Open Access Journals (Sweden)

    Niva Rani

    2016-06-01

    Full Text Available BACKGROUND Neonatal sepsis is defined as a clinical syndrome of bacteraemia with systemic signs and symptoms of infection in the first 4 weeks of life. Timely diagnosis of sepsis in neonates is critical as the illness can be rapidly progressive and in some instances fatal. The definitive diagnosis of septicaemia is made by a positive blood culture, which requires a minimum of 48-72 hours with a positive result in only 10-60% of cases. Haematological parameter can be evaluated for the early diagnosis of neonatal bacterial infection. AIMS The current study was undertaken to study the haematological parameters for early diagnosis of neonatal septicaemia using Rodwell’s scoring system with the aims and objectives of evaluating the Haematological Scoring System (HSS in early diagnosis of neonatal sepsis and to find out its significance. MATERIALS AND METHODS Prospective Hospital based cross-sectional study, carried out in the clinical haematology section of the Department of Pathology, Assam Medical College and Hospital (AMCH during the period of August 2013 to July 2014 with neonates suspected to have sepsis admitted in Neonatal Intensive Care Unit, (NICU. A total of 210 neonates suspected of having sepsis were enrolled in this study. Ethical Clearance for the study was obtained from Institutional Ethics Committee, AMCH, Dibrugarh, Assam and Informed written consent from legal guardians were obtained. Relevant maternal and neonatal histories were recorded in a predesigned and pretested proforma. Blood samples (2 mL were collected from the peripheral venous puncture within 24 hours of admission before initiation of antibiotic therapy and all necessary parameters were evaluated. STATISTICAL ANALYSIS The data obtained was tabulated using Microsoft Excel and tested through Chi-square test and Fisher Exact test when the expected frequencies are less than 5. RESULTS AND OBSERVATIONS The mean age of the study population was 2±1 days. In the present

  12. Integration of 3D scale-based pseudo-enhancement correction and partial volume image segmentation for improving electronic colon cleansing in CT colonograpy.

    Science.gov (United States)

    Zhang, Hao; Li, Lihong; Zhu, Hongbin; Han, Hao; Song, Bowen; Liang, Zhengrong

    2014-01-01

    Orally administered tagging agents are usually used in CT colonography (CTC) to differentiate residual bowel content from native colonic structures. However, the high-density contrast agents tend to introduce pseudo-enhancement (PE) effect on neighboring soft tissues and elevate their observed CT attenuation value toward that of the tagged materials (TMs), which may result in an excessive electronic colon cleansing (ECC) since the pseudo-enhanced soft tissues are incorrectly identified as TMs. To address this issue, we integrated a 3D scale-based PE correction into our previous ECC pipeline based on the maximum a posteriori expectation-maximization partial volume (PV) segmentation. The newly proposed ECC scheme takes into account both the PE and PV effects that commonly appear in CTC images. We evaluated the new scheme on 40 patient CTC scans, both qualitatively through display of segmentation results, and quantitatively through radiologists' blind scoring (human observer) and computer-aided detection (CAD) of colon polyps (computer observer). Performance of the presented algorithm has shown consistent improvements over our previous ECC pipeline, especially for the detection of small polyps submerged in the contrast agents. The CAD results of polyp detection showed that 4 more submerged polyps were detected for our new ECC scheme over the previous one.

  13. Nursing activities score

    NARCIS (Netherlands)

    Miranda, DR; Nap, R; de Rijk, A; Schaufeli, W; Lapichino, G

    2003-01-01

    Objectives. The instruments used for measuring nursing workload in the intensive care unit (e.g., Therapeutic Intervention Scoring System-28) are based on therapeutic interventions related to severity of illness. Many nursing activities are not necessarily related to severity of illness, and cost-ef

  14. Automated Essay Scoring

    Directory of Open Access Journals (Sweden)

    Semire DIKLI

    2006-01-01

    Full Text Available Automated Essay Scoring Semire DIKLI Florida State University Tallahassee, FL, USA ABSTRACT The impacts of computers on writing have been widely studied for three decades. Even basic computers functions, i.e. word processing, have been of great assistance to writers in modifying their essays. The research on Automated Essay Scoring (AES has revealed that computers have the capacity to function as a more effective cognitive tool (Attali, 2004. AES is defined as the computer technology that evaluates and scores the written prose (Shermis & Barrera, 2002; Shermis & Burstein, 2003; Shermis, Raymat, & Barrera, 2003. Revision and feedback are essential aspects of the writing process. Students need to receive feedback in order to increase their writing quality. However, responding to student papers can be a burden for teachers. Particularly if they have large number of students and if they assign frequent writing assignments, providing individual feedback to student essays might be quite time consuming. AES systems can be very useful because they can provide the student with a score as well as feedback within seconds (Page, 2003. Four types of AES systems, which are widely used by testing companies, universities, and public schools: Project Essay Grader (PEG, Intelligent Essay Assessor (IEA, E-rater, and IntelliMetric. AES is a developing technology. Many AES systems are used to overcome time, cost, and generalizability issues in writing assessment. The accuracy and reliability of these systems have been proven to be high. The search for excellence in machine scoring of essays is continuing and numerous studies are being conducted to improve the effectiveness of the AES systems.

  15. Perforation and mortality after cleansing enema for acute constipation are not rare but are preventable

    Directory of Open Access Journals (Sweden)

    Niv G

    2013-04-01

    Full Text Available Galia Niv,1 Tamar Grinberg,2 Ram Dickman,3 Nir Wasserberg,4 Yaron Niv1,3 1Risk Management and Quality Assurance, 2Emergency Department, 3Department of Gastroenterology, 4Department of Surgery B, Rabin Medical Center, Beilinson Hospital and Tel Aviv University, Tel Aviv, Israel Objectives: Constipation is a common complaint, frequently treated with cleansing enema. Enemas can be very effective but may cause serious adverse events, such as perforation or metabolic derangement. Our aim was to evaluate the outcome of the use of cleansing enema for acute constipation and to assess adverse events within 30 days of therapy. Methods: We performed a two-phase study: an initial retrospective and descriptive study in 2010, followed by a prospective study after intervention, in 2011. According to the results of the first phase we established guidelines for the treatment of constipation in the Emergency Department and then used these in the second phase. Results: There were 269 and 286 cases of severe constipation in the first and second periods of the study, respectively. In the first study period, only Fleet® Enema was used, and in the second, this was changed to Easy Go enema (free of sodium phosphate. There was a 19.2% decrease in the total use of enema, in the second period of the study (P < 0.0001. Adverse events and especially, the perforation rate and the 30-day mortality in patients with constipation decreased significantly in the second phase: 3 (1.4% versus 0 (P = 0.0001 and 8 (3.9% versus 2 (0.7% (P = 0.0001, for perforation and death in the first and second period of the study, respectively. Conclusion: Enema for the treatment of acute constipation is not without adverse events, especially in the elderly, and should be applied carefully. Perforation, hyperphosphatemia (after Fleet Enema, and sepsis may cause death in up to 4% of cases. Guidelines for the treatment of acute constipation and for enema administration are urgently needed. Keywords

  16. Thoracolumbar Tuberculosis: Implications for Appropriate Management based on Disease Location and Proposal of a Novel Scoring System

    Directory of Open Access Journals (Sweden)

    Shahryar Noordin

    2011-01-01

    Full Text Available Objective: To identify factors indicating disease severity in patients with thoracolumbar tuberculosis requiring surgical intervention.Design: Medical charts of patients who underwent surgery for thoracic and lumbar spinal tuberculosis from 1990-2005 were reviewed. Patients with different levels of disease were compared in terms of neurological deficits, duration of symptoms, previous antituberculous therapy, nutritional status and associated co-morbids.Results: Ninety-three patients aged 7-77 years (mean age 40 years were included. Thoracic spine was involved in 80% of operated patients, and lumbar spine in 20%. Severe neurological impairment (Frankel A to C was present in 68% of patients with thoracic disease, as compared to 5% with lumbar disease (p<0.05. Postoperatively, complete neurological recovery occurred in 65% with thoracic versus 100% with lumbar disease (p<0.05. Based on the disease location and pertinent elements in clinical history, physical signs, radiographic and biochemical features, a scoring system was developed.Conclusion: In endemic areas with limited resources, strategies for cost-effective care are needed. By objectively outlining the treatment approach, the judicious use of surgery offers hope for enormous cost savings in countries endemic for tuberculosis, averting complications from disease progression

  17. External validation and evaluation of reliability and validity of the S-ReSC scoring system to predict stone-free status after percutaneous nephrolithotomy.

    Directory of Open Access Journals (Sweden)

    Min Soo Choo

    Full Text Available OBJECTIVES: The Seoul National University Renal Stone Complexity (S-ReSC scoring system was developed to predict the stone-free rate (SFR after single-tract percutaneous nephrolithotomy (PCNL. This study is an external validation of this scoring system. MATERIALS AND METHODS: A retrospective review included 327 patients who underwent PCNL at 2 tertiary referral centers. The S-ReSC score was assigned from 1 to 9 based on the number of sites involved. The stone free status was defined as either complete clearance or clinically insignificant residual fragments <4 mm in size at 1 month follow-up imaging. Inter-observer and test-retest reliabilities were evaluated. The statistical performance of the prediction model was assessed by its predictive accuracy, predictive probability, and clinical usefulness. RESULTS: The overall SFR was 65.4%. SFRs were 83.9%, 47.6%, and 21.4% in low (1-2, intermediate (3-4, and high (5-9 score groups, respectively, with significant differences (P<0.001. Inter-observer and test-retest reliabilities revealed almost perfect agreements. External validation of the S-ReSC scoring system revealed an AUC of 0.731 (95% CI 0.675-0.788. The AUC of 3-titered S-ReSC score groups was 0.691 (95% CI, 0.629-0.753. The calibration plot showed that the predicted probability of SFR had a concordance comparable to that of the observed frequency. The Hosmer-Lemeshow goodness-of-fit statistic revealed an adequate performance of the predictive model (P = 0.10. Inter-observer and test-retest reliability showed a good level of agreement. CONCLUSIONS: The S-ReSC scoring system is useful in predicting the post-PCNL SFR and in describing the complexity of renal stones.

  18. The clinical performance of an office-based risk scoring system for fatal cardiovascular diseases in North-East of Iran.

    Directory of Open Access Journals (Sweden)

    Sadaf G Sepanlou

    Full Text Available Cardiovascular diseases (CVD are becoming major causes of death in developing countries. Risk scoring systems for CVD are needed to prioritize allocation of limited resources. Most of these risk score algorithms have been based on a long array of risk factors including blood markers of lipids. However, risk scoring systems that solely use office-based data, not including laboratory markers, may be advantageous. In the current analysis, we validated the office-based Framingham risk scoring system in Iran.The study used data from the Golestan Cohort in North-East of Iran. The following risk factors were used in the development of the risk scoring method: sex, age, body mass index, systolic blood pressure, hypertension treatment, current smoking, and diabetes. Cardiovascular risk functions for prediction of 10-year risk of fatal CVDs were developed.A total of 46,674 participants free of CVD at baseline were included. Predictive value of estimated risks was examined. The resulting Area Under the ROC Curve (AUC was 0.774 (95% CI: 0.762-0.787 in all participants, 0.772 (95% CI: 0.753-0.791 in women, and 0.763 (95% CI: 0.747-0.779 in men. AUC was higher in urban areas (0.790, 95% CI: 0.766-0.815. The predicted and observed risks of fatal CVD were similar in women. However, in men, predicted probabilities were higher than observed.The AUC in the current study is comparable to results of previous studies while lipid profile was replaced by body mass index to develop an office-based scoring system. This scoring algorithm is capable of discriminating individuals at high risk versus low risk of fatal CVD.

  19. Effect of yogic colon cleansing (Laghu Sankhaprakshalana Kriya on pain, spinal flexibility, disability and state anxiety in chronic low back pain

    Directory of Open Access Journals (Sweden)

    Richa Vivek Haldavnekar

    2014-01-01

    Conclusion: Clearing the bowel by yoga based colon cleansing technique (LSP is safe and offers immediate analgesic effect with reduced disability, anxiety and improved spinal flexibility in patients with CLBP.

  20. Development of a model based scoring system for diagnosis of canine disseminated intravascular coagulation with independent assessment of sensitivity and specificity

    DEFF Research Database (Denmark)

    Wiinberg, Bo; Jensen, Asger Lundorff; Johansson, Per Ingemar;

    2010-01-01

    A template for a scoring system for disseminated intravascular coagulation (DIC) in humans has been proposed by the International Society on Thrombosis and Haemostasis (ISTH). The objective of this study was to develop and validate a similar objective scoring system based on generally available...... coagulation tests for the diagnosis of DIC in dogs. To develop the scoring system, 100 dogs consecutively admitted to an intensive care unit (ICU) with diseases predisposing for DIC were enrolled prospectively (group A). The validation involved 50 dogs consecutively diagnosed with diseases predisposing...... for DIC, admitted to a different ICU (group B). Citrated blood samples were collected daily during hospitalisation and diagnosis of DIC was based on the expert evaluation of an extended coagulation panel. A multiple logistic regression model was developed in group A for DIC diagnosis. The integrity...

  1. A New Method for Evaluating Author’s Scientific Impact by using an Eigenfactor Derived Scoring System

    Directory of Open Access Journals (Sweden)

    Sorin Hostiuc

    2016-06-01

    Full Text Available Purpose: This paper aims to propose a new method of quantifying the scientific impact based on the Eigenfactor. Materials and Methods: We propose four scores, all based on a common parameter, called Emp: (1 article median score (AEmp computed by summing the Emps for all articles published by a researcher, (2 AEmp Main, which only includes the articles published as a main author by a specific researcher, (3 article weighted median score (BEmp, which is obtained by summing the Emp values of the journals in which the author has published, divided by the number of authors, and (4 citation weighted median score (CEmp, calculated by summing the Emp values of the journals in which the articles of the researcher were cited. We give t two calculation examples, for the Medicine, Legal, and Anatomy & Morphology ISI categories.

  2. OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging Studies. Core set of MRI acquisitions, joint pathology definitions, and the OMERACT RA-MRI scoring system

    DEFF Research Database (Denmark)

    Østergaard, Mikkel; Peterfy, C; Conaghan, P;

    2003-01-01

    This article describes the 2002 OMERACT rheumatoid arthritis magnetic resonance image scoring system (RAMRIS) for evaluation of inflammatory and destructive changes in RA hands and wrists, which was developed by an international MRI-OMERACT group. MRI definitions of important RA joint pathologies......, and a 'core set' of basic MRI sequences for use in RA are also suggested......This article describes the 2002 OMERACT rheumatoid arthritis magnetic resonance image scoring system (RAMRIS) for evaluation of inflammatory and destructive changes in RA hands and wrists, which was developed by an international MRI-OMERACT group. MRI definitions of important RA joint pathologies...

  3. A study of cleansing property of detergents on cotton, polyester and their blend

    Science.gov (United States)

    Patel, Vaishali P.

    Proper cleaning of clothes is one of the important aspects to be considered for increasing their life. Soil gets accumulated on textiles which needs to be cleaned for reusability. There are a variety of textile materials available and a variety brands of detergents for laundry purpose, to select the right brand is of much importance as it is based on detergent performance and money spent. The present study is an effort to determine which are the various popular brands of detergents, and to study the ability of cleaning property of a few of them. Eight brand of detergents namely: Ariel Microshine, Surf Excel, Surf, Super Nirma, Super Wheel with lemon, Hipolin, Rin were studied by artificially soiling of cotton, polyester and cotton/polyester blend fabrics, at four different concentration of soiling of washing with four different concentration of detergents. Both hand washing and machine washing technique was followed. All the detergent showed batter cleaning in hand washing technique in comparison with machine washing amongst all the various brands of detergents studied, Ariel Microshine show the best cleaning property, the poorest were Wheel and Rin. Ariel Microshine was the costliest of all. The best bargain in terms of cleansing property and price was Hipolin.

  4. Application of Ceria and Lanthana in Catalyst for Cleansing Exhaust Gas of Car

    Institute of Scientific and Technical Information of China (English)

    Yang Chunsheng; Chen Jianhua; Dai Shaojun

    2004-01-01

    The importanCe of rare earths being applied in the catalyst for cleansing the exhaust gas out of car was introduced. The acting mechanism of ceria and lanthana in catalyst and its influencing factors were discussed, and its prospect was forecasted. Pt-Rh precious metals three-way catalyst is widely used for decontaminating the exhaust gas of car now. Ceria and lanthana, which can decrease the content of Pt-Rh and increase the content of Pd in the catalyst, are used as additive in the decontaminating catalyst in order to solve the problem of the supply and demand of Pt and Rh.It is reported that increasing the activity of the coat on catalyst, regulating automatically the ratio of air and fuel, acting as catalyst-accelerator, and improving its properties such as thermal stability and strength may primarily amount for the catalyzing, mechanism of ceria and lanthana. The factors, such as their interaction, additive methods, and effects of cocatalyst ZrO2, CuO, AgO, etc. , will remarkably influence the catalyzing function of ceria and lanthana.

  5. Bowel cleansing before CT colonography: comparison between two minimal-preparation regimens

    Energy Technology Data Exchange (ETDEWEB)

    Iafrate, F.; Iannitti, M.; Ciolina, M.; Baldassari, P.; Pichi, A.; Laghi, A. [University of Rome, Department of Radiological Oncological and Pathological Sciences, Rome (Italy)

    2015-01-15

    To compare two regimens of reduced bowel preparation and faecal tagging for CT colonography. Single centre, prospective, randomized, noninferiority study, in which 52 consecutive adults underwent routine CT colonography. Patients, following a three-day low-fibre diet, received one of the two reduced preparations: 1-L polyethylene glycol and four tablets of bisacodyl in association with 90 mL of Iopamidol for faecal tagging administered on the same day as CTC examination (group 1); or a standard ''iodine-only'' preparation, consisting in 180 ml of Iopamidol the day before the examination (group 2). Primary outcome was the overall quality of bowel preparation. Twenty-six patients per group were included. Per segment analysis showed preparation of diagnostic quality in 97.4 % of segments in group 1 and in 95.5 % in group 2 (p = ns). Per-patient analysis showed optimal quality of preparation in 76.9 % of patients in group 1 and in 84.6 % in group 2 (p = ns). Patient tolerability to both preparations was not different. A limited bowel preparation consisting of 1-L PEG and four tablets of bisacodyl in association with 90 mL of Iodine for faecal tagging administered on the same day as CTC examination is feasible and offers bowel cleansing comparable to ''iodine-only'' preparation. (orig.)

  6. Combining the ASA Physical Classification System and Continuous Intraoperative Surgical Apgar Score Measurement in Predicting Postoperative Risk.

    Science.gov (United States)

    Jering, Monika Zdenka; Marolen, Khensani N; Shotwell, Matthew S; Denton, Jason N; Sandberg, Warren S; Ehrenfeld, Jesse Menachem

    2015-11-01

    The surgical Apgar score predicts major 30-day postoperative complications using data assessed at the end of surgery. We hypothesized that evaluating the surgical Apgar score continuously during surgery may identify patients at high risk for postoperative complications. We retrospectively identified general, vascular, and general oncology patients at Vanderbilt University Medical Center. Logistic regression methods were used to construct a series of predictive models in order to continuously estimate the risk of major postoperative complications, and to alert care providers during surgery should the risk exceed a given threshold. Area under the receiver operating characteristic curve (AUROC) was used to evaluate the discriminative ability of a model utilizing a continuously measured surgical Apgar score relative to models that use only preoperative clinical factors or continuously monitored individual constituents of the surgical Apgar score (i.e. heart rate, blood pressure, and blood loss). AUROC estimates were validated internally using a bootstrap method. 4,728 patients were included. Combining the ASA PS classification with continuously measured surgical Apgar score demonstrated improved discriminative ability (AUROC 0.80) in the pooled cohort compared to ASA (0.73) and the surgical Apgar score alone (0.74). To optimize the tradeoff between inadequate and excessive alerting with future real-time notifications, we recommend a threshold probability of 0.24. Continuous assessment of the surgical Apgar score is predictive for major postoperative complications. In the future, real-time notifications might allow for detection and mitigation of changes in a patient's accumulating risk of complications during a surgical procedure.

  7. A new scoring system for assessment of liver function after successful hepatectomy in patients with hepatocellular carcinoma

    Institute of Scientific and Technical Information of China (English)

    Zheng-GuiDu; BoLi; Yong-GangWei; JieYin; XiFeng; XiChen

    2011-01-01

    BACKGROUND: Whether a major liver resection is safe has been judged mainly from the patient's hepatic reserve. However, a safe limit for liver resection does not exist yet. This study aimed to construct a new scoring system as a guide to determine a safe limit for liver resection and avoid liver dysfunction after hepatectomy. METHODS: Eighty-six patients with hepatocellular carcinoma who had undergone hepatectomy in West China Hospital from March 2007 to June 2010 were reviewed. The patients were classified according to the levels of total bilirubin after hepatectomy and the parameters in the perioperative period were compared. Receiver operating characteristic (ROC) analysis was made to assess the liver function compensatory (LFC) value to predict liver dysfunction of the patients after hepatectomy. LFC value is defined as the preoperative KICG value×22.487+standard remnant liver volume (SRLV)×0.020. RESULTS: Patients were classified into group I (normal group, n=69) and group II (with total bilirubin >85.5 μmol/L for 7 days after hepatectomy, n=17) based on the levels of total bilirubin after hepatectomy. Group II was further divided into two subgroups: recovered subgroup (n=14) and fatal subgroup (n=3). There were no significant differences in preoperative data or intraoperative findings except the indocyanine green test parameters (KICG and ICG R15) and SRLV. ROC analysis showed that the sensitivity and specificity of an LFC value ≤13.01 were 94.1% and 82.6% respectively for predicting liver dysfunction of the patients after hepatectomy. CONCLUSIONS: The LFC value appears to be a good predictor of postoperative liver dysfunction in patients who undergo hepatectomy for HCC. An expected LFC value of 13.01 seems to be a safe limit for liver resection.

  8. Problems of "draw-a-person: a quantitative scoring system" (DAP:QSS) as a measure of intelligence.

    Science.gov (United States)

    Troncone, Alda

    2014-10-01

    There has been some ongoing debate on whether the DAP:QSS can be used to measure intelligence. The purpose of this study was to evaluate the concurrent validity of the DAP:QSS with Raven's Coloured Progressive Matrices (RCPM) and the DAP:QSS's accuracy as a predictor of RCPM scores and academic achievement. 184 children from two elementary schools in a region of Southern Italy was evaluated by the DAP:QSS, the RCPM, the Goodenough-Harris Drawing Test (GH), and school marks. Drawings' scores, school marks, and RCPM scores were subjected to a Pearson's correlation. Stepwise regression analyses were carried out to identify significant predictors of RCPM scores and school marks. After controlling for socioeconomic status, the DAP:QSS showed a significant correlation with the RCPM and GH tests and academic achievement. However, the modest correlations with the RCPM, the small amount of variance in RCPM scores accounted for by the DAP:QSS (R(2) = .24), and the errors of the DAP:QSS in correctly classifying participants with borderline/deficient intellectual functioning advise against the use of the DAP:QSS as a measure of intelligence. PMID:25350210

  9. A study of validity of a new scoring system of clock drawing test%画钟测验的评分方法探讨

    Institute of Scientific and Technical Information of China (English)

    郭起浩; 付建辉; 袁晶; 赵倩华; 曹歆轶; 洪震

    2008-01-01

    目的 编制和验证画钟测验(CDT)新的评分方法.方法 对188名健康中老年人、170例轻度认知障碍(MCI)患者和81例轻度阿尔茨海默病(AD)患者进行CDT等一系列神经心理测验.CDT 30分法包括先锚定12-3-6-9 4个点,称为"30分法-A",共4分;反映画钟结果的其余13项,称为"30分法-C",共26分,总分30分.38例被试者完成氙-CT(Xe-CT)检查,定量测量脑26个区域的局部血流量(rCBF).结果 CDT 30分法的14个项目分与总分的相关系数r=0.48~0.71,均有显著的相关性(P<0.01)."30分法-C"与空间知觉和执行功能指标的相关性较大(r=0.58~0.64),而"30分法-A"与记忆指标的相关性较大(r=0.67)."30分法-A"≤2分,识别MCI的敏感性为70.6%,特异性为73.9%,"30分法-C"≤17分,识别MCI的敏感性为38.2%,识别轻度AD的敏感性为75.3%,特异性为75.9%.CDT与Xe-CT检测的rCBF的关系:"30分法-A"和"30分法-C"的回归方程中,入选的自变量分别为左额叶下区和右白质区.结论 "30分法"A和C两部分具有不同的意义,"30分法-C"可用于识别AD,而"30分法-A"有助于MCI的识别.%Objective To set up and verify a new scoring system of clock drawing test(CDT).Methods CDT and other neuropsychological tests were applied to 180 normal individuals.170 subjects with mild cognitive impairment(MCI),and 31 patients with mild Alzheimer's disease(AD).The first step of the 30-score system of CDT was to anchor the 4 points of"12-3-6-9".totaling a score of 4 which was the "30-score system A(Anchoring)part";and the other 13 items reflecting the drawing results and totaling a score of 26 made up the so called"30-score system C(Clockfaee)part".the two together had a total score of 30.Thirty-eight subjects underwent Xe-enhanced computed tomography(Xe-CT)scanning for quantitively measuring regional cerebral blood flow(rCBF)of 26 regions of brain.Results Correlations coefficients of the scores of 14 items with the total score in 30-score system of CDT were

  10. Development of risk-based trading farm scoring system to assist with the control of bovine tuberculosis in cattle in England and Wales.

    Science.gov (United States)

    Adkin, A; Brouwer, A; Simons, R R L; Smith, R P; Arnold, M E; Broughan, J; Kosmider, R; Downs, S H

    2016-01-01

    Identifying and ranking cattle herds with a higher risk of being or becoming infected on known risk factors can help target farm biosecurity, surveillance schemes and reduce spread through animal trading. This paper describes a quantitative approach to develop risk scores, based on the probability of infection in a herd with bovine tuberculosis (bTB), to be used in a risk-based trading (RBT) scheme in England and Wales. To produce a practical scoring system the risk factors included need to be simple and quick to understand, sufficiently informative and derived from centralised national databases to enable verification and assess compliance. A logistic regression identified herd history of bTB, local bTB prevalence, herd size and movements of animals onto farms in batches from high risk areas as being significantly associated with the probability of bTB infection on farm. Risk factors were assigned points using the estimated odds ratios to weight them. The farm risk score was defined as the sum of these individual points yielding a range from 1 to 5 and was calculated for each cattle farm that was trading animals in England and Wales at the start of a year. Within 12 months, of those farms tested, 30.3% of score 5 farms had a breakdown (sensitivity). Of farms scoring 1-4 only 5.4% incurred a breakdown (1-specificity). The use of this risk scoring system within RBT has the potential to reduce infected cattle movements; however, there are cost implications in ensuring that the information underpinning any system is accurate and up to date.

  11. OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging Studies. Core set of MRI acquisitions, joint pathology definitions, and the OMERACT RA-MRI scoring system

    DEFF Research Database (Denmark)

    Østergaard, Mikkel; Peterfy, C; Conaghan, P;

    2003-01-01

    This article describes the 2002 OMERACT rheumatoid arthritis magnetic resonance image scoring system (RAMRIS) for evaluation of inflammatory and destructive changes in RA hands and wrists, which was developed by an international MRI-OMERACT group. MRI definitions of important RA joint pathologies......, and a 'core set' of basic MRI sequences for use in RA are also suggested...

  12. Experience acquired over a four-year period using Vichi's scoring system in chest alterations occurring in patients with cystic fibrosis

    International Nuclear Information System (INIS)

    The classification of chest alterations in Cystic Fibrosis (CF) and related score proposed by Chrispin and Norman has been widely adopted in Europe and is still applied (although slightly modified) in most European Centres. Brasfield classification instead has been monstly used in the USA. Lately, however, to revise both classifications, the need has been felt, for a more precise correlation to anatomo-radiological data as well as for inclusion of headings which have not been taken into account so far. In 1980 one of the authors (Vichi) worked out a new scoring system for the chest alterations of CF. Results are reported from a follow-up of 15 patients with CF carried out at the FC Center of Meyer Ospedale in Florence from the late 1981 to 1985. The patients underwent periodic checking including determination of clinical scoring system-according to Shwachman and Kulczychi modified by Doershuk-respiratory function tests, chest X-rays evaluated by three radiologists separately, following both Chrispin and Norman and Vichi scoring systems. The latter system has proved to be well correlated to clinical data and to the ordinary pulmonary function tests but it mainly presents a high observer reproducibility

  13. An image based system to automatically and objectivelly score the degreeof redness and scaling in psoriasi lesions

    DEFF Research Database (Denmark)

    Gomez, David Delgado; Ersbøll, Bjarne Kjær; Carstensen, Jens Michael

    2004-01-01

    In this work, a combined statistical and image analysis method to automatically evaluate the severity of scaling in psoriasis lesions is proposed. The method separates the different regions of the disease in the image and scores the degree of scaling based on the properties of these areas. The pr...

  14. MICROBIOLOGICAL EVALUATION OF THE EFFECTIVENESS OF COMMERCIALLY AVAILABLE DENTURE CLEANSING AGENTS

    Directory of Open Access Journals (Sweden)

    Chethan M D

    2011-06-01

    Full Text Available Purpose: The purpose of this study was conducted to compare and evaluate the efficacy of four chemically different immersion types of commercially available denture cleansers on recently fabricated complete dentures in healthy patients, using microbiological quantification method. Materials and Methods: Ten healthy subjects aged 60 – 70 year were selected. Chemical denture cleansers used were divided into four groups; Group I – Sodium hypochlorite solution 0.02% , Group II – Trisodium phosphate , Group III – Sodium perborate and Group IV – Chlorhexidine gluconate 0.2%. Posterior half of the tissue – bearing surface of the denture was swabbed using sterile cotton swabs at four different sites and cultured on blood agar .Net percentage reduction in the colony forming units before and after treatment with each of the above test agents on cultures from above four sites was calculated, tabulated and subjected to statistical analysis Results For all the groups the difference of means were statistically significant. The percentage reduction in streptococcus species count in log units for Groups I, II, III, and IV was found to be 28%, 16%, 10%, and 9% respectively. Conclusion: Cleansing agents were found to be effective in the following order, Sodium hypochlorite solution (0.02%, Trisodium phosphate, Sodium perborate and Chlorhexidine gluconate (0.2%. Clinical Implications: Treatment of dentures with denture cleansers significantly decreases the amount of subsequently formed plaque. The significant reduction in the number of microorganisms observed in this study suggests that the use of chemical cleansers is suitable method for cleaning dentures in geriatric patients.

  15. Inter-reader agreement of multi-parametric MR imaging for the detection of prostate cancer. Evaluation of a scoring system

    International Nuclear Information System (INIS)

    Purpose: Functional prostate MR is performed in varying combinations of T2-weighted images with diffusion-weighted imaging (DWI), dynamic contrast-enhanced MRI (DCE-MRI), and spectroscopic imaging (MRSI). Recently, a European consensus meeting proposed the use of a simple 5-point scale for estimating the probability of a lesion being malignant. The aim of the present study was to determine the inter-reader agreement of MR imaging using a scoring system based on the recommendations of the consensus. Materials and Methods: The appearance of 108 predefined lesions in three different MR sequences (T2-weighted images, DWI, and DCE-MRI) in 50 functional prostate MR examinations were retrospectively scored by three blinded radiologists using a 5-point scale for each MR sequence. After scoring T2/DWI and T2/DWI/DCE-MRI, every lesion was graded based on its probability for malignancy. The inter-observer reliability was evaluated using Kappa statistics (Κ). Results: With respect to T2-weighted images, DWI and DCE-MRI Κ was 0.49, 0.97, and 0.77, respectively. Combined scoring of T2-weighted images and DWI demonstrated correct tumor diagnosis (true positive) in 71 - 88 % (depending on reader) of cases (Κ = 0.78). The accuracy was further improved to 88 - 96 % after scoring all three MR sequences including DCE-MRI (Κ = 0.90). Conclusion: The use of a simple 5-point scoring system for T2-weighted images, DWI, and DCE-MRI is feasible in functional prostate MRI and has high inter-observer reliability.

  16. Liver dysfunction assessed by model for end-stage liver disease excluding INR (MELD-XI scoring system predicts adverse prognosis in heart failure.

    Directory of Open Access Journals (Sweden)

    Satoshi Abe

    Full Text Available AIMS: Liver dysfunction due to heart failure (HF is often referred to as cardiac or congestive hepatopathy. The composite Model for End-Stage Liver Disease excluding INR (MELD-XI is a robust scoring system of liver function, and a high score is associated with poor prognosis in advanced HF patients with a heart transplantation and/or ventricular assist device. However, the impact of MELD-XI on the prognosis of HF patients in general remains unclear. METHODS AND RESULTS: We retrospectively analyzed 562 patients who were admitted to our hospital for the treatment of decompensated HF. A MELD-XI score was graded, and patients were divided into two groups based on the median value of MELD-XI score: Group L (MELD-XI <10, n = 289 and Group H (MELD-XI ≥10, n = 273. We compared all-cause mortality and echocardiographic findings between the two groups. In the follow-up period (mean 471 days, 104 deaths (62 cardiac deaths and 42 non-cardiac deaths were observed. The event (cardiac death, non-cardiac death, all-cause death-free rate was significantly higher in group L than in group H (logrank P<0.05, respectively. In the Cox proportional hazard analysis, a high MELD-XI score was found to be an independent predictor of cardiac deaths and all-cause mortality in HF patients. Regarding echocardiographic parameters, right atrial and ventricular areas, inferior vena cava diameter, and systolic pulmonary artery pressure were higher in group H than in group L (P<0.05, respectively. CONCLUSIONS: The MELD-XI scoring system, a marker of liver function, can identify high-risk patients with right heart volume overload, higher pulmonary arterial pressure and multiple organ failure associated with HF.

  17. Effects of Treatment Intensification on Acute Local Toxicity During Radiotherapy for Head and Neck Cancer: Prospective Observational Study Validating CTCAE, Version 3.0, Scoring System

    International Nuclear Information System (INIS)

    Purpose: To quantify the incidence and severity of acute local toxicity in head and neck cancer patients treated with radiotherapy (RT), with or without chemotherapy (CHT), using the Common Terminology Criteria for Adverse Events, version 3.0 (CTCAE v3.0), scoring system. Methods and Materials: Between 2004 and 2006, 149 patients with head and neck cancer treated with RT at our center were prospectively evaluated for local toxicity during treatment. On a weekly basis, patients were monitored and eight toxicity items were recorded according to the CTCAE v3.0 scoring system. Of the 149 patients, 48 (32%) were treated with RT alone (conventional fractionation), 82 (55%) with concomitant CHT and conventional fractionation RT, and 20 (13%) with accelerated-fractionation RT and CHT. Results: Severe (Grade 3-4) adverse events were recorded in 28% (mucositis), 33% (dysphagia), 40% (pain), and 12% (skin) of patients. Multivariate analysis showed CHT to be the most relevant factor independently predicting for worse toxicity (mucositis, dysphagia, weight loss, salivary changes). In contrast, previous surgery, RT acceleration and older age, female gender, and younger age, respectively, predicted for a worse outcome of mucositis, weight loss, pain, and dermatitis. The T-score method confirmed that conventional RT alone is in the 'low-burden' class (T-score = 0.6) and suggests that concurrent CHT and conventional fractionation RT is in the 'high-burden' class (T-score = 1.15). Combined CHT and accelerated-fractionation RT had the highest T-score at 1.9. Conclusions: The CTCAE v3.0 proved to be a reliable tool to quantify acute toxicity in head and neck cancer patients treated with various treatment intensities. The effect of CHT and RT acceleration on the acute toxicity burden was clinically relevant

  18. Inter-reader agreement of multi-parametric MR imaging for the detection of prostate cancer. Evaluation of a scoring system

    Energy Technology Data Exchange (ETDEWEB)

    Quentin, M.; Roehlen, S.; Klasen, J.; Antoch, G.; Blondin, D. [Duesseldorf Univ. (Germany). Inst. fuer Diagnostische und Interventionelle Radiologie; Arsov, C.; Albers, P. [Duesseldorf Univ. (Germany). Urologische Klinik

    2012-10-15

    Purpose: Functional prostate MR is performed in varying combinations of T2-weighted images with diffusion-weighted imaging (DWI), dynamic contrast-enhanced MRI (DCE-MRI), and spectroscopic imaging (MRSI). Recently, a European consensus meeting proposed the use of a simple 5-point scale for estimating the probability of a lesion being malignant. The aim of the present study was to determine the inter-reader agreement of MR imaging using a scoring system based on the recommendations of the consensus. Materials and Methods: The appearance of 108 predefined lesions in three different MR sequences (T2-weighted images, DWI, and DCE-MRI) in 50 functional prostate MR examinations were retrospectively scored by three blinded radiologists using a 5-point scale for each MR sequence. After scoring T2/DWI and T2/DWI/DCE-MRI, every lesion was graded based on its probability for malignancy. The inter-observer reliability was evaluated using Kappa statistics ({Kappa}). Results: With respect to T2-weighted images, DWI and DCE-MRI {Kappa} was 0.49, 0.97, and 0.77, respectively. Combined scoring of T2-weighted images and DWI demonstrated correct tumor diagnosis (true positive) in 71 - 88 % (depending on reader) of cases ({Kappa} = 0.78). The accuracy was further improved to 88 - 96 % after scoring all three MR sequences including DCE-MRI ({Kappa} = 0.90). Conclusion: The use of a simple 5-point scoring system for T2-weighted images, DWI, and DCE-MRI is feasible in functional prostate MRI and has high inter-observer reliability.

  19. 研究型教学柔性评分方案研究%A Flexible Performance Scoring System of Research-teaching Mode

    Institute of Scientific and Technical Information of China (English)

    周治; 樊树海; Amanda Elizabeth

    2013-01-01

    The essence of research-teaching mode is to bring up the creative spirit and ability of students.However,the current student performance scoring system can not reflect the general real condition of students' mastering the knowledge.And it does not fit for the research-teaching mode.Learning from the classical scoring method,"square-root with 10 times",and a flexible scoring system for research-teaching mode was proposed,where student's contribution was adopted and reflected to the power function.Then the computation formula was deduced and the design scheme of the scoring system was also given.With the computerization,upgrading mode and a WYSWYG exhibition methods,this flexible performance scoring system was implemented.It brought forward an active classroom climate and extracurricular research activity.%研究型教学的本质是培养学生创新的精神与能力,而现行的学生成绩评分体系差异度较小,不能全面反映出学生的真实掌握情况,不能适应研究型教学模式的开展.借鉴“开根乘十”的经典处理案例,提出了一种将贡献值反映到幂次上的适合研究型教学的柔性评分系统,对其进行方案设计,并推导扩展了其评分计算公式.结合升级模式,对其进行自动实现,以所见即所得的方式进行展示,活跃了课堂气氛,也充分调动了学生课后进行研究探索活动的积极性.

  20. Predictive power of the ESUR scoring system for prostate cancer diagnosis verified with targeted MR-guided in-bore biopsy

    International Nuclear Information System (INIS)

    Highlights: • The PI-RADS summed score (PSsum) demonstrated very good diagnostic values, especially for higher grade PCa. • Lesions with PSsum ≥13 represented prostate cancer in 88% and higher grade prostate cancer in 42%. • Sensitivity and NPV was nearly 100% for higher grade PCa detection using a cut-off limit of PSsum 10. • Peripheral zone lesions demonstrated better diagnostic value with the PSsum compared to transitional zone lesions. • Further improvement of the PI-RADS score is required to prevent unnecessary overdiagnosis. - Abstract: Purpose: This study evaluates the diagnostic value of the ESUR scoring system (PI-RADS) regarding prostate cancer detection using MR-guided in-bore biopsies (IB-GB) as the reference standard. Methods: 566 lesions in 235 consecutive patients (65.7 ± 7.9 years, PSA 9.9 ± 8.5 ng/ml) with a multiparametric (mp)-MRI (T2WI, DWI, DCE) of the prostate at 3 T were scored using the PI-RADS scoring system. PI-RADS single (PSsingle), summed (PSsum), and overall (PSoverall) scores were determined. All lesions were histologically verified by IB-GB. Results: Lesions with a PSsum below 9 contained no prostate cancer (PCa) with Gleason score (GS) ≥ 4 + 3 = 7. A PSsum of 13–15 (PSoverall V) resulted in 87.8% (n = 108) in PCa and in 42.3% (n = 52) in GS ≥ 4 + 3 = 7. Transition zone (TZ) lesions with a PSsum of 13–15 (PSoverall V) resulted in 76.3% (n = 36) in PCa and in 26.3% (n = 10) in GS ≥ 4 + 3 = 7, whereas for peripheral zone (PZ) lesions cancer detection rate at this score was 92.9% (n = 79) and 49.4% (n = 42) for GS ≥ 4 + 3 = 7. Using a threshold of PSsum ≥ 10, sensitivity was 86.0%, and negative predictive value (NPV) was 86.2%. For higher grade PCa sensitivity was 98.6%, and NPV was 99.5%. Conclusion: A PSsum below 9 excluded a higher grade PCa, whereas lesions with a PSsum ≥ 13 (PSoverall V) represented in 88% PCa, and in 42% higher grade PCa. The PSsum or PSoverall demonstrated a better diagnostic value

  1. Evaluation of probabilistic flow predictions in sewer systems using grey box models and a skill score criterion

    DEFF Research Database (Denmark)

    Thordarson, Fannar Ørn; Breinholt, Anders; Møller, Jan Kloppenborg;

    2012-01-01

    to the diffusion term description up to a 4 h prediction horizon by adopting the prediction performance measures; reliability, sharpness and skill score to pinpoint the preferred model. The prediction performance of a model is reliable if the observed coverage of the prediction intervals corresponds to the nominal...... coverage of the prediction intervals, i.e. the bias between these coverages should ideally be zero. The sharpness is a measure of the distance between the lower and upper prediction limits, and skill score criterion makes it possible to pinpoint the preferred model by taking into account both reliability...... term and a diffusion term, respectively accounting for the deterministic and stochastic part of the models. Furthermore, a distinction is made between the process noise and the observation noise. We compare five different model candidates’ predictive performances that solely differ with respect...

  2. Hypoxia-inducible factor-1-regulated protein expression and oligodendroglioma patient outcome: comparison with established biomarkers and preoperative UCSF low-grade scoring system.

    Science.gov (United States)

    Abraham, Shirley; Hu, Nan; Jensen, Randy

    2012-07-01

    Methods for predicting outcome for patients with oligodendrogliomas and anaplastic oligodendrogliomas (AOs) are limited. Hypoxia-inducible factor-1α (HIF-1α) controls many proteins involved in glycolysis and angiogenesis including VEGF, Glut-1, and CA-IX. We examined whether expression of HIF-1α and other hypoxia-regulated molecules (HRM) can predict overall (OS) and progression-free (PFS) survival. We correlated these data with more established biomarkers and a published preoperative scoring system. We prospectively collected tissue samples and followed outcomes of 50 patients with oligodendrogliomas and 32 with AOs. Tumor tissues were stained for measures of proliferative index, microvascular density, IDH-1 mutational status, and HRMs. We retrospectively analyzed preoperative imaging and clinical data based on the UCSF Scoring System (good prognostic indicators: Karnofsky Performance Scale (KPS) score > 80, age oligodendrogliomas. Both 1p19q codeletion and IDH-1 mutation predict outcome of patients with both oligodendroglioma and AO. The UCSF score is a strong predictor for oligodendrogliomas patient outcome and is strengthened by IDH-1 and 1p19q status. Glut-1 may be useful in predicting PFS in AOs. Proliferation index >5 for oligodendrogliomas and KPS ≤ 80 for AOs predict a worse prognosis. Immunohistochemical markers of HRMs show a significantly higher expression in anaplastic variants of oligodendrogliomas and may contribute to the prediction of survival in these patients.

  3. Fetal Biophysical Profile Scoring

    Directory of Open Access Journals (Sweden)

    H.R. HaghighatKhah

    2009-01-01

    significance. Fetal breathing movements, amniotic fluid volume, and the non-stress test are the most powerful variables. For example, when the biophysical profile score is 2, the perinatal mortality varies between 428/1000 with only fetal movement present to 66/1000 if the non-stress test is reactive and all of the ultrasound parameters are absent (Manning 1990b. Some authors have, therefore, proposed utilization of a modified biophysical profile that incorporates only the non-stress test and amniotic fluid volume (Miller 1996. Although the positive predictive value of these 2 tests is equivalent to a biophysical profile score of 6, the perinatal mortality is still increased over a normal test score of 8 or 10 (Manning 1990b. The false positive rate with the modified biophysical profile score is also substantially higher. "nConclusions: The fetus expresses its well being or compromised status through a number of different biophysical activities that are controlled by different central nervous system centers. The utilization of the biophysical score for antepartum surveillance in high-risk patients has resulted in a reduction in perinatal mortality when compared to historical controls. The appropriate management of the viable fetus with an abnormal biophysical profile score may also decrease long-term neurological morbidity (Manning 1998. "nIt is unlikely that in the future additional variables will be added to the biophysical profile score. However, perhaps the incorporation of the fetal state (i.e., eye movements and Doppler flow studies of specific fetal vessels (umbilical artery, middle cerebral artery, ductus venosus will be incorporated into a complete assessment of the fetal condition "n "nTable 1. Components of the 30 Minute Biophysical Profile Score "nComponent "nDefinition "nFetal movements "n> 3 body or limb movements "nFetal tone "nOne episode of active extension and flexion of the limbs; opening and closing of hand "nFetal breathing movements "n>1 episode of >30

  4. Serum interleukin-18 and interleukin-10 levels in systemic lupus erythematosus: correlation with SLEDAI score and disease activity parameters

    Directory of Open Access Journals (Sweden)

    Sahar Abou El-Fetouh

    2014-01-01

    Conclusion The circulating IL-18 and IL-10 concentrations were significantly elevated in SLE patients and correlated with the SLEDAI score. The study emphasized that there exists an upregulated proinflammatory as well as anti-inflammatory responses in patients with active SLE; however, the anti-inflammatory response is not enough to suppress the active disease. Identifying the exact contribution of the currently studied cytokines might provide future insights for targeted therapeutic strategies in SLE.

  5. Decompositions of Proper Scores

    CERN Document Server

    Bröcker, Jochen

    2008-01-01

    Scoring rules are an important tool for evaluating the performance of probabilistic forecasts. A popular example is the Brier score, which allows for a decomposition into terms related to the sharpness (or information content) and to the reliability of the forecast. This feature renders the Brier score a very intuitive measure of forecast quality. In this paper, it is demonstrated that all strictly proper scoring rules allow for a similar decomposition into reliability and sharpness related terms. This finding underpins the importance of proper scores and yields further credence to the practice of measuring forecast quality by proper scores. Furthermore, the effect of averaging multiple probabilistic forecasts on the score is discussed. It is well known that the Brier score of a mixture of several forecasts is never worse that the average score of the individual forecasts. This property hinges on the convexity of the Brier score, a property not universal among proper scores. Arguably, this phenomenon portends...

  6. Comparison of Hay’s Criteria with Nugent’s Scoring System for Diagnosis of Bacterial Vaginosis

    Directory of Open Access Journals (Sweden)

    Rohit Chawla

    2013-01-01

    Full Text Available Although Nugent’s criterion is considered as the gold standard for the diagnosis of bacterial vaginosis (BV, the method requires an experienced slide reader and considerable time and skill. In this study, we compared the method of Hay and Ison with Nugent’s scoring criteria. Vaginal specimens were collected from a total of 213 women, presenting with or without the symptoms of vaginitis. Diagnosis of BV was done using Nugent’ and Hay’s method. Sensitivity, specificity, and predictive values for positive and negative test were calculated for Hay’s method using Nugent’s method as the gold standard. We diagnosed 70 cases (32.86% of BV by Nugent’s method and 87 (40.85% cases by the Hay’s method. Sensitivity, specificity, predictive value of positive result, predictive value of negative result, and Kappa value when evaluating Hay’s criteria using Nugent’s criteria as the gold standard were ≥97.2%, ≥88.1%, ≥80.4%, ≥97.1%, and ≥0.830, respectively, when Hay’s grade II and/or Nugent’s intermediate score were considered either as negative or positive or excluded. Using Nugent score for the intermediate group is the most difficult. Hay’s method shows good agreement with the gold standard method of Nugent et al. and can be used as an alternative to Nugent’s criteria in busy tertiary care hospitals.

  7. Proposal of criteria to select candidates with colorectal liver metastases for hepatic resection: Comparison of our scoring system to the positive number of risk factors

    Institute of Scientific and Technical Information of China (English)

    Ikuo Nagashima; Tadahiro Takada; Miki Adachi; Hirokazu Nagawa; Tetsuichiro Muto; Kota Okinaga

    2006-01-01

    AIM: To select accurately good candidates of hepatic resection for colorectal liver metastasis.METHODS: Thirteen clinicopathological features, which were recognized only before or during surgery, were selected retrospectively in 81 consecutive patients in one hospital (Group Ⅰ ). These features were entered into a multivariate analysis to determine independent and significant variables affecting long-term prognosis after hepatectomy. Using selected variables, we created a scoring formula to classify patients with colorectal liver metastases to select good candidates for hepatic resection. The usefulness of the new scoring system was examined in a series of 92 patients from another hospital (Group Ⅱ ), comparing the number of selected variables.RESULTS: Among 81 patients of Group Ⅰ, multivariate analysis, i.e. Cox regression analysis, showed that multiple tumors, the largest tumor greater than 5 cm in diameter, and resectable extrahepatic metastases were significant and independent prognostic factors for poor survival after hepatectomy (P < 0.05). In addition, these three factors: serosa invasion, local lymph node metastases of primary cancers, and postoperative disease free interval less than 1 year including synchronous hepatic metastasis, were not significant,however, they were selected by a stepwise method of Cox regression analysis (0.05 < P < 0.20). Using these six variables, we created a new scoring formula to classify patients with colorectal liver metastases. Finally,our new scoring system not only classified patients in Group Ⅰ very well, but also that in Group Ⅱ, according to long-term outcomes after hepatic resection. The positive number of these six variables also classified them well.CONCLUSION: Both, our new scoring system and the positive number of significant prognostic factors are useful to classify patients with colorectal liver metastases in the preoperative selection of good candidates for hepatic resection.

  8. Biointervention makes leather processing greener: an integrated cleansing and tanning system.

    Science.gov (United States)

    Thanikaivelan, Palanisamy; Rao, Jonnalagadda Raghava; Nair, Balachandran Unni; Ramasami, Thirumalachari

    2003-06-01

    The do-undo methods adopted in conventional leather processing generate huge amounts of pollutants. In other words, conventional methods employed in leather processing subject the skin/hide to wide variations in pH. Pretanning and tanning processes alone contribute more than 90% of the total pollution from leather processing. Included in this is a great deal of solid wastes such as lime and chrome sludge. In the approach described here, the hair and flesh removal as well as fiber opening have been achieved using biocatalysts at pH 8.0 for cow hides. This was followed by a pickle-free chrome tanning, which does not require a basification step. Hence, this tanning technique involves primarily three steps, namely, dehairing, fiber opening, and tanning. It has been found that the extent of hair removal, opening up of fiber bundles, and penetration and distribution of chromium are comparable to that produced by traditional methods. This has been substantiated through scanning electron microscopic, stratigraphic chrome distribution analysis, and softness measurements. Performance of the leathers is shown to be on par with conventionally processed leathers through physical and hand evaluation. Importantly, softness of the leathers is numerically proven to be comparable with that of control. The process also demonstrates reduction in chemical oxygen demand load by 80%, total solids load by 85%, and chromium load by 80% as compared to the conventional process, thereby leading toward zero discharge. The input-output audit shows that the biocatalytic three-step tanning process employs a very low amount of chemicals, thereby reducing the discharge by 90% as compared to the conventional multistep processing. Furthermore, it is also demonstrated that the process is technoeconomically viable.

  9. Biointervention makes leather processing greener: an integrated cleansing and tanning system.

    Science.gov (United States)

    Thanikaivelan, Palanisamy; Rao, Jonnalagadda Raghava; Nair, Balachandran Unni; Ramasami, Thirumalachari

    2003-06-01

    The do-undo methods adopted in conventional leather processing generate huge amounts of pollutants. In other words, conventional methods employed in leather processing subject the skin/hide to wide variations in pH. Pretanning and tanning processes alone contribute more than 90% of the total pollution from leather processing. Included in this is a great deal of solid wastes such as lime and chrome sludge. In the approach described here, the hair and flesh removal as well as fiber opening have been achieved using biocatalysts at pH 8.0 for cow hides. This was followed by a pickle-free chrome tanning, which does not require a basification step. Hence, this tanning technique involves primarily three steps, namely, dehairing, fiber opening, and tanning. It has been found that the extent of hair removal, opening up of fiber bundles, and penetration and distribution of chromium are comparable to that produced by traditional methods. This has been substantiated through scanning electron microscopic, stratigraphic chrome distribution analysis, and softness measurements. Performance of the leathers is shown to be on par with conventionally processed leathers through physical and hand evaluation. Importantly, softness of the leathers is numerically proven to be comparable with that of control. The process also demonstrates reduction in chemical oxygen demand load by 80%, total solids load by 85%, and chromium load by 80% as compared to the conventional process, thereby leading toward zero discharge. The input-output audit shows that the biocatalytic three-step tanning process employs a very low amount of chemicals, thereby reducing the discharge by 90% as compared to the conventional multistep processing. Furthermore, it is also demonstrated that the process is technoeconomically viable. PMID:12831051

  10. Development and application of scoring system for academic conference papers%学术会议论文评分系统的开发与应用

    Institute of Scientific and Technical Information of China (English)

    杨杰; 周骅; 王晓幸; 郭双洋; 王勤美; 周翔天

    2008-01-01

    目的 建立学术会议论文评分系统,以实现大中型学术会议中通过计算机网络进行论文实时评分的信息化管理需求.方法 采用Microsoft .Net技术,建立基于计算机网络、支持多会场、多评分客户端和大屏幕动态显示的学术会议论文评分系统.结果 建立的系统可以自由设置会议信息、会场名称、会议评分标准及规则,具有显示当前选手及论文信息、自动计时、超时提醒、实时显示评分结果、动态排名等功能,经多次在国内大型眼科专业学术会议实际应用,获得会议组委会及评委的好评.结论 学术会议论文评分系统可显著提高学术会议论文评分的工作效率,有助于推动评分工作的标准化,体现公开、公平、公正的学术会议评分原则,值得大力推广.%Objective To develop a Scoring System for Academic Conference Papers,in order to achieve real-time paper scoring in large academic conference with the information technology and network.Methods Based on Microsoft.Net technology,an information system Was developed,supporting multimeeting.multi-client and dynamic screen show.Results In this system,the conference inforrnation,meeting name and scoring standards Call be customized;the doctor information,papers information,used time,score detail and dynamic list Can be displayed in the screen.This system has been applied in national ophthalmic conferences several times and gained praise from the organizing committee and judges.Conclusions The scoring system for Academic Conference Papers can significantly improve efficiency,help to promote the standardization of paper scoring,and manifest the open,fair and just principles.It is worth of spreading.

  11. Reoccupying Public Space by Hatred and Ethnic Cleansing. Case study: Banja Luka

    Directory of Open Access Journals (Sweden)

    Srđan Šušnica

    2013-03-01

    Full Text Available The article analyses the symbolism and the meaning of ethno-religious graffiti, slogans and stickers especially as they are used on the streets of Banja Luka. The city used to be a strategic centre for armed forces but is today the political centre of Republika Srpska (RS, supposedly a legitimate military conquest of the people of Serbia. Responses in ethno-religious graffiti can be turbulent. In our case, narrative and visual codes transmit dominant messages and myths of the Serbian ethnical corpus which can easily become hate speech, especially in the post-war context, in which ethno-religious differences are being brought to the fore, war crimes and armed victories are being exalted and expressions of non-tolerance are common. This aggressive visibility of »ours« pushes all the rest and anyone who is different into invisibility and self-censoring. The article researches characteristics and the quality of connection between the production and the results of ethno-fascistic speech in graffiti and in the messages of the RS ethno-political elites in public forums, regulations and media spaces. A contextual interpretation of a graffiti discourse, which was formed in the midst of civil war, ethnic cleansing, attacks on and the separation of Bosnia and Herzegovina and activities of political elites in RS, is offered. The intimate connection between street discourse and that of political elites shows that a populist legitimization of the activities of the RS is still a political goal that also triggers the process of forgetting the region’s multi-ethnic past. In Banja Luka, this process offers a »national and spiritual« legitimacy for the existence of RS and seeks to make the city a part of the Serbian ethnic community. It offers an unconvincing cultural-political and war-emancipatory »continuity« and »normality« for the RS and covers up its real intention of bloodshed from which it had emerged. In this it is consistent with Eco’s notion

  12. A Quick Phenotypic Neurological Scoring System for Evaluating Disease Progression in the SOD1-G93A Mouse Model of ALS.

    Science.gov (United States)

    Hatzipetros, Theo; Kidd, Joshua D; Moreno, Andy J; Thompson, Kenneth; Gill, Alan; Vieira, Fernando G

    2015-01-01

    The SOD1-G93A transgenic mouse is the most widely used animal model of amyotrophic lateral sclerosis (ALS). At ALS TDI we developed a phenotypic screening protocol, demonstrated in video herein, which reliably assesses the neuromuscular function of SOD1-G93A mice in a quick manner. This protocol encompasses a simple neurological scoring system (NeuroScore) designed to assess hindlimb function. NeuroScore is focused on hindlimb function because hindlimb deficits are the earliest reported neurological sign of disease in SOD1-G93A mice. The protocol developed by ALS TDI provides an unbiased assessment of onset of paresis (slight or partial paralysis), progression and severity of paralysis and it is sensitive enough to identify drug-induced changes in disease progression. In this report, the combination of a detailed manuscript with video minimizes scoring ambiguities and inter-experimenter variability thus allowing for the protocol to be adopted by other laboratories and enabling comparisons between studies taking place at different settings. We believe that this video protocol can serve as an excellent training tool for present and future ALS researchers. PMID:26485052

  13. Development and validation of a clinical scoring system for predicting risk of HCC in asymptomatic individuals seropositive for anti-HCV antibodies.

    Directory of Open Access Journals (Sweden)

    Mei-Hsuan Lee

    Full Text Available BACKGROUND: The development of a risk assessment tool for long-term hepatocellular carcinoma risk would be helpful in identifying high-risk patients and providing information of clinical consultation. METHODS: The model derivation and validation cohorts consisted of 975 and 572 anti-HCV seropositives, respectively. The model included age, alanine aminotransferase (ALT, the ratio of aspirate aminotransferase to ALT, serum HCV RNA levels and cirrhosis status and HCV genotype. Two risk prediction models were developed: one was for all-anti-HCV seropositives, and the other was for anti-HCV seropositives with detectable HCV RNA. The Cox's proportional hazards models were utilized to estimate regression coefficients of HCC risk predictors to derive risk scores. The cumulative HCC risks in the validation cohort were estimated by Kaplan-Meier methods. The area under receiver operating curve (AUROC was used to evaluate the performance of the risk models. RESULTS: All predictors were significantly associated with HCC. The summary risk scores of two models derived from the derivation cohort had predictability of HCC risk in the validation cohort. The summary risk score of the two risk prediction models clearly divided the validation cohort into three groups (p<0.001. The AUROC for predicting 5-year HCC risk in the validation cohort was satisfactory for the two models, with 0.73 and 0.70, respectively. CONCLUSION: Scoring systems for predicting HCC risk of HCV-infected patients had good validity and discrimination capability, which may triage patients for alternative management strategies.

  14. Value of CT to predict surgically important bowel and/or mesenteric injury in blunt trauma: performance of a preliminary scoring system

    Energy Technology Data Exchange (ETDEWEB)

    Faget, Claire; Taourel, Patrice; Ruyer, Alban; Alili, Chakib; Millet, Ingrid [CHU Lapeyronie, Department of Medical Imaging, Montpellier (France); Charbit, Jonathan [CHU Lapeyronie, Department of Intensive Care and Anesthesiology, Montpellier (France); Molinari, Nicolas [UMR 729 MISTEA, CHU Montpellier, Department of Medical Information and Statistics, Montpellier (France)

    2015-12-15

    To evaluate the performance of a computed tomography (CT) diagnostic score to predict surgical treatment for blunt bowel and/or mesentery injury (BBMI) in consecutive abdominal trauma. This was a retrospective observational study of 805 consecutive abdominal traumas with 556 patients included and screened by an abdominal radiologist blinded to the patient outcome, to evaluate numerous CT findings and calculate their diagnostic performances. These CT findings were compared using univariate and multivariate analysis between patients who had a laparotomy-confirmed BBMI requiring surgical repair, and those without BBMI requiring surgery. A CT score was obtained with an internal bootstrap validation. Fifty-six patients (10.1 %) had BBMI requiring surgery. Nine CT signs were independently associated with BBMI requiring surgery and were used to develop a CT diagnostic score. The AUC of our model was 0.98 (95 % CI 0.96-100), with a ≥5 cut-off. Its diagnostic performance was determined by internal validation: sensitivity 91.1-100 %, specificity 85.7-97.6 %, positive predictive value 41.4-82.3 % and negative predictive value 98.9-100 %. Bowel wall discontinuity and mesenteric pneumoperitoneum had the strongest association with BBMI requiring surgery (OR = 128.9 and 140.5, respectively). We developed a reliable CT scoring system which is easy to implement and highly predictive of BBMI requiring surgery. (orig.)

  15. The aggregate effect of dopamine genes on dependence symptoms among cocaine users: Cross-validation of a candidate system scoring approach

    OpenAIRE

    Derringer, Jaime; Robert F Krueger; Dick, Danielle M; Aliev, Fazil; Grucza, Richard A.; Saccone, Scott; Agrawal, Arpana; Edenberg, Howard J.; Goate, Alison M.; Hesselbrock, Victor M.; Kramer, John R.; Lin, Peng; Neuman, Rosalind J; Nurnberger, John I.; Rice, John P.

    2012-01-01

    Genome-wide studies of psychiatric conditions frequently fail to explain a substantial proportion of variance, and replication of individual SNP effects is rare. We demonstrate a selective scoring approach, in which variants from several genes known to directly affect the dopamine system are considered concurrently to explain individual differences in cocaine dependence symptoms. 273 SNPs from eight dopamine-related genes were tested for association with cocaine dependence symptoms in an init...

  16. Development of a model based scoring system for diagnosis of canine disseminated intravascular coagulation with independent assessment of sensitivity and specificity.

    Science.gov (United States)

    Wiinberg, Bo; Jensen, Asger L; Johansson, Pär I; Kjelgaard-Hansen, Mads; Rozanski, Elizabeth; Tranholm, Mikael; Kristensen, Annemarie T

    2010-09-01

    A template for a scoring system for disseminated intravascular coagulation (DIC) in humans has been proposed by the International Society on Thrombosis and Haemostasis (ISTH). The objective of this study was to develop and validate a similar objective scoring system based on generally available coagulation tests for the diagnosis of DIC in dogs. To develop the scoring system, 100 dogs consecutively admitted to an intensive care unit (ICU) with diseases predisposing for DIC were enrolled prospectively (group A). The validation involved 50 dogs consecutively diagnosed with diseases predisposing for DIC, admitted to a different ICU (group B). Citrated blood samples were collected daily during hospitalisation and diagnosis of DIC was based on the expert evaluation of an extended coagulation panel. A multiple logistic regression model was developed in group A for DIC diagnosis. The integrity and diagnostic accuracy of the model was subsequently evaluated in a separate prospective study at a different ICU (group B) and was carried out according to The Standards for Reporting of Diagnostic Accuracy (STARD) criteria. Thirty-seven dogs were excluded from group A and four from group B due to missing data. Based on expert opinion, 23/63 dogs (37%) had DIC. The final multiple logistic regression model was based on activated partial thromboplastin time, prothrombin time, D-Dimer and fibrinogen. The model had a diagnostic sensitivity and specificity of 90.9% and 90.0%, respectively. The diagnostic accuracy of the model was sustained by prospective evaluation in group B (sensitivity 83.3%, specificity 77.3%). Based on commonly used, plasma-based coagulation assays, it was possible to design an objective diagnostic scoring system for canine DIC with a high sensitivity and specificity.

  17. A Study of Experimental Chemistry Scoring System Based on Improved FAHP%基于改进的FAHP的实验化学测评体系研究

    Institute of Scientific and Technical Information of China (English)

    聂丽华; 林毅; 冯辉荣; 游秀花; 蔡向阳

    2014-01-01

    The scoring system's scientificity ,comprehensiveness ,fairness and operability will have a significant influence on students'learning interest ,cultivation of innovative skills ,,development of operational ability , and enthusiasm ,etc .This article has improved the existing scoring system of experimental chemistry based on improved fuzzy analytical hierarchy process (FAHP) and uses three -demarcation method to ensure the influence that assessment criteria has on the assessment objectives ,w hich aims to build an experimental chemistry scoring system that is more practical and beneficial to the training of students .%指出了评分体系制定的科学性、全面性、公平性与可操作性,将会对学生的学习兴趣、创新能力的培养、动手能力的提高、积极性的调动等方面产生重要影响。利用改进的模糊层次分析法(FAHP),对已有的实验化学测评体系进行了改进,运用三标度法,确定了各评价指标对于评价目标的影响程度,制定出了较符合实际情况、有利于学生培养的实验化学测评体系。

  18. The thromboelastometric discrepancy between septic and trauma induced disseminated intravascular coagulation diagnosed by the scoring system from the Japanese association for acute medicine.

    Science.gov (United States)

    Koami, Hiroyuki; Sakamoto, Yuichiro; Sakurai, Ryota; Ohta, Miho; Imahase, Hisashi; Yahata, Mayuko; Umeka, Mitsuru; Miike, Toru; Nagashima, Futoshi; Iwamura, Takashi; Yamada, Kosuke Chris; Inoue, Satoshi

    2016-08-01

    The aim of this study is to evaluate the hematological differences between septic and traumatic disseminated intravascular coagulation (DIC) using the rotational thromboelastometry (ROTEM).This retrospective study includes all sepsis or severe trauma patients transported to our emergency department who underwent ROTEM from 2013 to 2014. All patients were divided into 2 groups based on the presence of DIC diagnosed by the Japanese Association for Acute Medicine (JAAM) DIC score. We statistically analyzed the demographics, clinical characteristics, laboratory data, ROTEM findings (EXTEM and FIBTEM), and outcome.Fifty-seven patients (30 sepsis and 27 severe trauma) were included in primary analysis. Sepsis cases were significantly older and had higher systemic inflammatory response syndrome (SIRS) scores, whereas there were no significant differences in other parameters including Acute Physiology and Chronic Health Evaluation (APACHE) II score, sequential organ failure assessment (SOFA) score. Twenty-six patients (14 sepsis and 12 severe trauma) were diagnosed with DIC. The Septic DIC (S-DIC) group was significantly older and had higher DIC scores than the traumatic DIC (T-DIC) group. Hematologic examination revealed significantly higher CRP, fibrinogen, lower FDP, DD, and higher FDP/DD ratio were found in the S-DIC group in comparison with the T-DIC group. ROTEM findings showed that the A10, A20, and MCF in the FIBTEM test were significantly higher in the S-DIC group. However, no statistical differences were confirmed in the LI30, LI45, and ML in EXTEM test.The plasma fibrinogen level and fibrinogen based clot firmness in whole-blood test revealed statistical significance between septic and traumatic DIC patients. PMID:27495106

  19. Electrochemical Methods for Cleansing of H2S and SO2 in Industrial and Natural Contaminated Waters

    Science.gov (United States)

    Petrov, Konstantin

    Hydrogen sulfide and sulfur dioxide are hazardous to the environment pollutants. They are contained in industrial and utility waste gases and waters as well as in some natural lakes and Seas. The present paper is a review of our studies on the electrochemical oxidation-reduction processes for SO2 and H2S cleansing by their oxidation with oxygen contained in the air. An innovative Carbon-Teflon structure of the electrodes (membranes) allows for the simultaneous electro-catalytic reactions of SO2, H2S and oxygen, proceeding on dispersed micro-galvanic elements, based on their chemical affinity without external power application. The physical model of electrochemical reactions in Carbon-Teflon electrodes is presented. The electrochemical nature of the processes is revealed using the additive principle. The results are used for development of processes for purification of SO2 and H2S from industrial gasses and waters. The major relations describing the processes, namely the impacts of sulfur dioxide and sulfuric acid concentrations have been studied. The revealed simplified expressions facilitate the performance estimation of an innovative process for SO2 cleansing in waste gases, labeled ELCOX.

  20. Electronic cleansing for CT colonography: does it help CAD software performance in a high-risk population for colorectal cancer?

    Energy Technology Data Exchange (ETDEWEB)

    Wi, Jae Yeon [Seoul National University College of Medicine, Department of Radiology, Jongno-gu, Seoul (Korea); Kim, Se Hyung; Lee, Jae Young; Han, Joon Koo; Choi, Byung Ihn [Seoul National University College of Medicine, Department of Radiology, Jongno-gu, Seoul (Korea); Seoul National University Hospital, Institute of Radiation Medicine, Seoul (Korea); Kim, Sang Gyun [Seoul National University Hospital, Department of Internal Medicine, Seoul (Korea)

    2010-08-15

    To compare the performance of computer-aided detection (CAD) for CT colonography (CTC) with and without electronic cleansing (EC) in a high-risk population tagged with a faecal tagging (FT) protocol. Thirty-two patients underwent CTC followed by same-day colonoscopy. All patients underwent bowel preparation and FT with barium and gastrografin. Each CTC dataset was processed with colon CAD with and without EC. Per-polyp sensitivity was calculated. The average number of false-positive (FP) results and their causes were also analysed and compared. Eighty-six polyps were detected in 29 patients. Per-polyp sensitivities of CAD with EC (93.8% and 100%) were higher than those without EC (84.4% and 87.5%) for polyps {>=}6 mm and {>=}10 mm, respectively. However, the differences were not significant. The average number (6.3) of FPs of CAD with EC was significantly larger than that (3.1) without EC. The distribution of FPs in both CAD settings was also significantly different. The most common cause of FPs was the ileocaecal valve in both datasets. However, untagged faeces was a significantly less common cause of FPs with EC, EC-related artefacts being more common. Electronic cleansing has the potential to improve per-polyp sensitivity of CTC CAD, although the significantly larger number of FPs with EC remains to be improved. (orig.)

  1. Impact of Scoring Single or Multiple Occlusal Lesions on Estimates of Diagnostic Accuracy of the Visual ICDAS-II System

    Directory of Open Access Journals (Sweden)

    Anahita Jablonski-Momeni

    2009-01-01

    differ in appearance and severity. This study aimed to evaluate how estimates of reproducibility and accuracy of ICDAS-II were affected when all lesions on occlusal surfaces, or only a representative lesion, were scored. 100 permanent teeth with 1–4 investigation sites on the occlusal surface were examined visually by four examiners. Serial sections of the teeth were assessed for lesion depth. Intra- and interexaminer reproducibility (weighted kappa values, sensitivity, and specificity were calculated for all investigation sites and for a randomly selected site per tooth. Comparing the kappa values for the whole sample and the independent sites, no effect or only a small effect was found. Comparing the areas under the ROC-curves no effect could be shown. Examining multiple sites on teeth leads to results comparable to when a single independent site is chosen per tooth.

  2. Critical Overview of the Risk Scoring Systems to Predict Non-Responsiveness to Intravenous Immunoglobulin in Kawasaki Syndrome

    Directory of Open Access Journals (Sweden)

    Donato Rigante

    2016-02-01

    Full Text Available Kawasaki syndrome (KS is the most relevant cause of heart disease in children living in developed countries. Intravenous immunoglobulin (IVIG has a preventive function in the formation of coronary artery abnormalities and a poor strictly-curative action in established coronary damage. More than two decades ago, the Harada score was set to assess which children with KS should be subject to administration of IVIG, evaluating retrospectively a large cohort of patients with regard to age, sex and laboratory data. Nowadays, high dose IVIG is administered to all children with a confirmed diagnosis of KS, but a tool for predicting non-responsiveness to the initial infusion of IVIG has not been found. The prediction of IVIG resistance is a crucial issue, as recognising these high-risk patients should consent the administration of an intensified initial treatment in combination with IVIG in order to prevent coronary injuries. Few reports have focused on factors, referring to both clinical parameters and laboratory data at the onset of KS, in order to predict which patients might be IVIG non-responsive. We have analysed three different risk scores which were formulated to predict IVIG resistance in Japanese children with typical KS, but their application in non-Japanese patients or in those with incomplete and atypical patterns of the disease has been studied in a fragmentary way. Overall, our analysis showed that early and definite ascertainment of likely IVIG non-responders who require additional therapies reducing the development of coronary artery involvement in children with KS is still a challenge.

  3. Overexpression of epidermal growth factor receptor as a prognostic factor in colorectal cancer on the basis of the Allred scoring system

    Directory of Open Access Journals (Sweden)

    Rokita M

    2013-07-01

    Full Text Available Marta Rokita,1 Rafal Stec,1 Lubomir Bodnar,1 Radoslaw Charkiewicz,2 Jan Korniluk,1 Marta Smoter,1 Marzena Cichowicz,3 Lech Chyczewski,4 Jacek Nikliński,2 Wojciech Kozłowski,3 Cezary Szczylik11Department of Oncology, Military Institute of Medicine, Central Teaching Hospital, Warsaw, Poland; 2Department of Clinical Molecular Biology, Medical University of Bialystok, Bialystok, Poland; 3Department of Pathology, Military Institute of the Health Services in Warsaw, Warsaw, Poland; 4Department of Clinical Pathology, Medical University of Bialystok, Bialystok, PolandBackground: Overexpression of epidermal growth factor receptor (EGFR is found in many types of neoplasms. The aim of the study was to evaluate EGFR expression in colorectal cancer (CRC specimens and to determine whether EGFR expression correlates with clinicopathological data and overall survival.Patients and methods: Tissue specimens from 181 consecutive CRC patients treated at the Military Institute of Medicine in 2006–2010 were collected and examined for EGFR expression, by immunohistochemistry staining. The staining intensity and percentage of cells with membranous EGFR expression were scored and then grouped according to the parameters of the Allred Scoring system. Cutoff values were subjected to further statistical analysis. Univariate tests and a multivariate Cox proportional hazards model were used in data analysis.Results: EGFR was overexpressed in 96 of 181 CRC specimens (53%. EGFR expression was not correlated with other clinicopathological variables. On univariate analysis, overexpression of EGFR, determined by PS (percentage score (>3 and total score (sum of PS and intensity score (>4, was associated with poor overall survival. On multivariate analysis, EGFR overexpression (PS > 3 was an independent adverse prognostic factor (hazard ratio [HR] 1.62; 95% confidence interval [CI]: 1.03–2.53. Elevated carcinoembryonic antigen (CEA serum concentration before treatment

  4. Fingermark evidence evaluation based on automated fingerprint identification system matching scores: the effect of different types of conditioning on likelihood ratios.

    Science.gov (United States)

    Alberink, Ivo; de Jongh, Arent; Rodriguez, Crystal

    2014-01-01

    In recent studies, the evidential value of the similarity of minutiae configurations of fingermarks and fingerprints, for example expressed by automated fingerprint identification systems (AFIS), is determined by likelihood ratios (LRs). The paper explores whether there is an effect on LRs if conditioning takes place on specified fingers, fingerprints, or fingermarks under competing hypotheses: In addition, an approach is explored where conditioning is asymmetric. Comparisons between fingerprints and simulated fingermarks with eight minutiae are performed to produce similarity score distributions for each type of conditioning, given a fixed AFIS matching algorithm. Both similarity scores and LRs are significantly different if the conditioning changes. Given a common-source scenario, "LRs" resulting from asymmetric conditioning are on average higher. The difference may reach a factor of 2000. As conditioning on a suspect's finger(print) is labor-intensive and requires a cooperating suspect, it is recommended to just condition on the number of minutiae in the fingermark. PMID:24180303

  5. Electronic timing and scoring system and its application%体育电子计时记分系统及应用

    Institute of Scientific and Technical Information of China (English)

    王茂利

    2014-01-01

    With theadvent of information and the development of the information agerequirements,electronic timing and scoring system has become a sports match most basic technical support system,to the smooth progress of events is crucial.This paper briefly describes the sports competition in timing and scoring system design principles,system composition, main functions of the system and its application in the field of sports.%随着信息时代的到来及信息发展的要求,电子计时记分系统已经成为体育比赛最基本的技术支持系统,对赛事的顺利进行至关重要。本文简要地阐述了体育竞赛中必备的计时记分系统的设计原则、系统组成、主要功能以及在体育领域中的应用。

  6. Alberta卒中项目早期CT评分系统及其应用%Alberta Stroke Program Early CT Score system and its application

    Institute of Scientific and Technical Information of China (English)

    王崇; 董瑞国

    2010-01-01

    Alberta卒中项目早期CT评分(Alberta Stroke Program Early CT Score,ASPECTS)是评价缺血性卒中患者大脑中动脉供血区早期缺血改变的一种简单、可靠和系统的方法,可对缺血性病变快速进行半定量评价,有助于判定溶栓效果和远期预后.多模式CT和MRI技术的发展丰富了ASPECTS的应用范围,提高了病情判断的有效性和可靠性.后循环急性卒中预后早期CT评分的开发使快速评分扩展到后循环卒中,这有利于对所有缺血性卒中患者进行早期影像学评分.文章对ASPECTS系统的原理、组成及其在多模式CT和MRI中的应用以及后循环评分进行了综述.%The Alberta Stroke Program Early CT Score (ASPECTS) is a simple, reliable and systematic approach for evaluating early ischemic changes in middle cerebral artery territory in patients with ischemic stroke. It can be used to conduct rapid semi-quantitative evaluation of ischemic lesions and help to determine the thrombolytic effect and long-term prognosis. The development of multimodal CT and MRI techniques have enriched the application scope of ASPECTS and have improved the validity and reliability of disease judgment. The development of the posterior circulation Acute Stroke Prognosis Early CT Score has made the fast scores extend to posterior circulation stroke, which is beneficial for all the patients with ischemic stroke to conduct early imaging scores. This article reviews the principle of the ASPECTS system, composition, its application in multimodal CT and MRI, as well as the posterior circulation scores.

  7. The use of follicle score system in IVF-ET%卵泡评分系统在IVF-ET中的应用

    Institute of Scientific and Technical Information of China (English)

    牛志宏; 高芹; 冯云

    2001-01-01

    目的:检验用体外受精-胚胎移植(IVF-ET)周期治疗的患者,注射hCG日血清E2浓度及双侧卵泡分值作为指标预测OHSS发生的可行性。方法:对40例实施IVF-ET的患者分别测定注射hCG日血清E2和双侧卵泡的大小,使用卵泡评分系统,探讨卵泡分值与血清E2水平的相关性以及2种指标在预测早发型OHSS中的价值。结果:2种指标的相关系数为0.939,以E2作为指标进行预测,阳性预测值和阴性预测值分别为42.9%和93.6%,以卵泡分值为指标,阳性预测值和阴性预测值分别为40%和91.4%。结论:卵泡分值与血清E2水平有良好的相关性,二种指标均可预测OHSS的发生。%Objective: To explore the use of the concentration of E2 in serum and follicular score on the day of hCG injection as indications to forecast the occurrence of OHSS. Methods: Measure the concentration of E2 in serum and follicular score on the day of hCG injection,usefollicular score system to find the correlation of follicular score and E2 andto find the value of them on the forecast the occurrence of OHSS. Results: The coefficient of correlation of two indications was 0.939. The positiveand negative predicted value were 42.9% and 93.6% when use E2 as indication,while they are 40% and 91.4% when use follicular score. Conclusions: Follicular score has good correlation with E2 concentration in serum, and two indications can predict the occurrence of OHSS.

  8. Predictive power of the ESUR scoring system for prostate cancer diagnosis verified with targeted MR-guided in-bore biopsy

    Energy Technology Data Exchange (ETDEWEB)

    Schimmöller, L., E-mail: Lars.Schimmoeller@med.uni-duesseldorf.de [Univ Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Moorenstr. 5, D-40225 Dusseldorf (Germany); Quentin, M., E-mail: Michael.Quentin@med.uni-duesseldorf.de [Univ Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Moorenstr. 5, D-40225 Dusseldorf (Germany); Arsov, C., E-mail: Cristian.Arsov@med.uni-duesseldorf.de [Univ Dusseldorf, Medical Faculty, Department of Urology, Moorenstr. 5, D-40225 Dusseldorf (Germany); Hiester, A., E-mail: Andreas.Hiester@med.uni-duesseldorf.de [Univ Dusseldorf, Medical Faculty, Department of Urology, Moorenstr. 5, D-40225 Dusseldorf (Germany); Kröpil, P., E-mail: Patric.Kroepil@med.uni-duesseldorf.de [Univ Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Moorenstr. 5, D-40225 Dusseldorf (Germany); Rabenalt, R., E-mail: Robert.Rabenalt@med.uni-duesseldorf.de [Univ Dusseldorf, Medical Faculty, Department of Urology, Moorenstr. 5, D-40225 Dusseldorf (Germany); Albers, P., E-mail: urologie@uni-duesseldorf.de [Univ Dusseldorf, Medical Faculty, Department of Urology, Moorenstr. 5, D-40225 Dusseldorf (Germany); Antoch, G., E-mail: Antoch@med.uni-duesseldorf.de [Univ Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Moorenstr. 5, D-40225 Dusseldorf (Germany); Blondin, D., E-mail: Dirk.Blondin@sk-mg.de [Univ Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Moorenstr. 5, D-40225 Dusseldorf (Germany)

    2014-12-15

    Highlights: • The PI-RADS summed score (PS{sub sum}) demonstrated very good diagnostic values, especially for higher grade PCa. • Lesions with PS{sub sum} ≥13 represented prostate cancer in 88% and higher grade prostate cancer in 42%. • Sensitivity and NPV was nearly 100% for higher grade PCa detection using a cut-off limit of PS{sub sum} 10. • Peripheral zone lesions demonstrated better diagnostic value with the PS{sub sum} compared to transitional zone lesions. • Further improvement of the PI-RADS score is required to prevent unnecessary overdiagnosis. - Abstract: Purpose: This study evaluates the diagnostic value of the ESUR scoring system (PI-RADS) regarding prostate cancer detection using MR-guided in-bore biopsies (IB-GB) as the reference standard. Methods: 566 lesions in 235 consecutive patients (65.7 ± 7.9 years, PSA 9.9 ± 8.5 ng/ml) with a multiparametric (mp)-MRI (T2WI, DWI, DCE) of the prostate at 3 T were scored using the PI-RADS scoring system. PI-RADS single (PS{sub single}), summed (PS{sub sum}), and overall (PS{sub overall}) scores were determined. All lesions were histologically verified by IB-GB. Results: Lesions with a PS{sub sum} below 9 contained no prostate cancer (PCa) with Gleason score (GS) ≥ 4 + 3 = 7. A PS{sub sum} of 13–15 (PS{sub overall} V) resulted in 87.8% (n = 108) in PCa and in 42.3% (n = 52) in GS ≥ 4 + 3 = 7. Transition zone (TZ) lesions with a PS{sub sum} of 13–15 (PS{sub overall} V) resulted in 76.3% (n = 36) in PCa and in 26.3% (n = 10) in GS ≥ 4 + 3 = 7, whereas for peripheral zone (PZ) lesions cancer detection rate at this score was 92.9% (n = 79) and 49.4% (n = 42) for GS ≥ 4 + 3 = 7. Using a threshold of PS{sub sum} ≥ 10, sensitivity was 86.0%, and negative predictive value (NPV) was 86.2%. For higher grade PCa sensitivity was 98.6%, and NPV was 99.5%. Conclusion: A PS{sub sum} below 9 excluded a higher grade PCa, whereas lesions with a PS{sub sum} ≥ 13 (PS{sub overall} V) represented in 88

  9. The Apgar Score.

    Science.gov (United States)

    2015-10-01

    The Apgar score provides an accepted and convenient method for reporting the status of the newborn infant immediately after birth and the response to resuscitation if needed. The Apgar score alone cannot be considered as evidence of, or a consequence of, asphyxia; does not predict individual neonatal mortality or neurologic outcome; and should not be used for that purpose. An Apgar score assigned during resuscitation is not equivalent to a score assigned to a spontaneously breathing infant. The American Academy of Pediatrics and the American College of Obstetricians and Gynecologists encourage use of an expanded Apgar score reporting form that accounts for concurrent resuscitative interventions.

  10. Risk Behaviors, Occupational Risk and Seroprevalence of Hepatitis B and A Infections among Public Cleansing Workers of Bangkok Metropolis

    Directory of Open Access Journals (Sweden)

    Pipat Luksamijarulkul

    2008-02-01

    Full Text Available Background and Aims: Public cleansing workers, especially public garbage collectors are probably at risk for hepatitis B virus (HBV and/or hepatitis A virus (HAV infections. This study was designed to assess risky behaviors, occupational risk and seroprevalence of HBV and HAV infections in this group.Methods: 354 public cleansing workers of Bangkok Metropolis (185 cleaners and 169 garbage collectors were randomly selected by multi-stage sampling. The subjects were interviewed and their blood pecimens were collected to investigate HBV seromarkers (HBsAg, anti-HBs and anti-HBc and anti-HAV by voluntary participation.Results: Out of 354 workers, 22.6% had tattoos, 15.8% had a history of regular alcohol consumption, and 6.8% had a history of extramarital sex without using condoms in a previous year. Public garbage collectors had relatively higher percentage than public cleaners. Also, public garbage collectors had significantly higher percentage of occupational risks including a history of contact with blood, a history of contact with used condom, syringe or needle, and a history of needle stick or sharp puncture than public cleaners (P= 0.0018, 0.0067 & 0.0012, respectively. Results from blood screening revealed 49.4% of HBV seropositivity, 5.9% of HBsAg, 37.3% of anti-HBs, 6.2% of anti-HBc only, and 85% of anti-HAV antibody. Public garbage collectors had significantly higher HBV seropositivity than public cleaners (P=0.0058, while there was no statistical significance in anti-HAV positivity between groups. Risk factors for HBV seropositiveness after multivariate analysis were occupation (adjusted OR=1.76, P=0.0027, a history of contact with used condom, syringe or needle (adjusted OR=3.02, P<0.0001, and a history of needle stick or sharp puncture (adjusted OR=4.21, P<0.0001.Conclusions: This study supported public cleansing workers; especially public garbage collectors were at risk for HBV and/or HAV infections. The risk reduction programs

  11. Gene-load score of the renin-angiotensin-aldosterone system is associated with coronary heart disease in familial hypercholesterolaemia

    NARCIS (Netherlands)

    J.B. van der Net (Jeroen); J. van Etten (Jeroen); M. Yazdanpanah (Mojgan); G.M. Dallinga-Thie (Geesje); J.J.P. Kastelein (John); J.C. Defesche (Joep); R.P. Koopmans (Richard); E.W. Steyerberg (Ewout); E.J.G. Sijbrands (Eric)

    2008-01-01

    textabstractAims: Familial hypercholesterolaemia (FH) is characterized by premature coronary heart disease (CHD). However, the incidence of CHD varies considerably among FH patients. Genetic variation in the renin-angiotensin-aldosterone system (RAAS) and the adrenalin/noradrenalin system may be of

  12. Primary uncleansed 2D versus primary electronically cleansed 3D in limited bowel preparation CT-colonography. Is there a difference for novices and experienced readers?

    International Nuclear Information System (INIS)

    The purpose of this study was to compare a primary uncleansed 2D and a primary electronically cleansed 3D reading strategy in CTC in limited prepped patients. Seventy-two patients received a low-fibre diet with oral iodine before CT-colonography. Six novices and two experienced observers reviewed both cleansed and uncleansed examinations in randomized order. Mean per-polyp sensitivity was compared between the methods by using generalized estimating equations. Mean per-patient sensitivity, and specificity were compared using the McNemar test. Results were stratified for experience (experienced observers versus novice observers). Mean per-polyp sensitivity for polyps 6 mm or larger was significantly higher for novices using cleansed 3D (65%; 95%CI 57-73%) compared with uncleansed 2D (51%; 95%CI 44-59%). For experienced observers there was no significant difference. Mean per-patient sensitivity for polyps 6 mm or larger was significantly higher for novices as well: respectively 75% (95%CI 70-80%) versus 64% (95%CI 59-70%). For experienced observers there was no statistically significant difference. Specificity for both novices and experienced observers was not significantly different. For novices primary electronically cleansed 3D is better for polyp detection than primary uncleansed 2D. (orig.)

  13. Observational multicentric study to evaluate efficacy, adverse effects and acceptance of bowel cleansing prior to colonoscopy with sodium picosulfate / magnesium citrate formulation CitraFleet®.

    Science.gov (United States)

    Janisch, H D; Koppold, B; Deissler, H; Riemann, J F

    2016-01-01

    The various efficient methods available for bowel preparation prior to colonoscopy differ in patient acceptance. Combining the laxative sodium picosulfate with hyperosmotic magnesium citrate, used in this study in the formulation CitraFleet(®), allows the uptake of the purgative substances as a solution of low volume. This observational study with 737 patients evaluated efficacy of bowel preparation, potential side or adverse effects and patient acceptance of this medicinal product when used by resident physicians in Germany.Colon cleansing with CitraFleet(®) was considered very good to sufficient in 95.2 % of the patients and inadequate in only 4.8 %. In 75 % of the colonoscopies, bowel preparation was rated very good or good. Compared to the standard regimen of two portions taken the day before endoscopy, cleaning efficacy was better when patients received one of the doses on the morning of the day of colonoscopy. The quality of bowel preparation was rated lower by gastroenterologists without any prior experience with sodium picosulfate/magnesium citrate. The overall assessment of the colon cleansing procedure by the 76 participating physicians was very positive and patient acceptance was also very high which can be considered a clear advantage over alternative methods. Efficacy of colon cleansing with CitraFleet(®) was not substantially affected by typical deviations from the recommended standard procedure, emphasizing the robustness of the method. Only one of the patients reported a mild adverse effect potentially caused by the cleansing agents.

  14. Efficacy of cleansing agents in killing microorganisms in mixed species biofilms present on silicone facial prostheses-an in vitro study

    NARCIS (Netherlands)

    Ariani, Nina; Visser, Anita; Teulings, Margot R. I. M.; Dijk, Melissa; Rahardjo, Tri Budi W.; Vissink, Arjan; van der Mei, Henny C.

    2015-01-01

    The purpose of this study was to assess the efficacy of different cleansing agents in killing mixed species biofilms on silicone facial prostheses. Two bacterial and three yeast strains, isolated from silicone facial prostheses, were selected for the mixed species biofilms. A variety of agents used

  15. Primary uncleansed 2D versus primary electronically cleansed 3D in limited bowel preparation CT-colonography. Is there a difference for novices and experienced readers?

    NARCIS (Netherlands)

    A.H. de Vries; M.H. Liedenbaum; S. Bipat; R. Truyen; I.W.O. Serlie; R.H. Cohen; S.G.C. van Elderen; A. Heutinck; O. Kesselring; W. de Monyé; L. te Strake; T. Wiersma; J. Stoker

    2009-01-01

    The purpose of this study was to compare a primary uncleansed 2D and a primary electronically cleansed 3D reading strategy in CTC in limited prepped patients. Seventy-two patients received a low-fibre diet with oral iodine before CT-colonography. Six novices and two experienced observers reviewed bo

  16. The influence of cleansing shampoos on ethyl glucuronide concentration in hair analyzed with an optimized and validated LC-MS/MS method.

    Science.gov (United States)

    Binz, Tina M; Baumgartner, Markus R; Kraemer, Thomas

    2014-11-01

    Ethyl glucuronide (EtG) is widely used as a marker for assessment of alcohol consumption behavior. In this study the influence of special cleansing shampoos on ethyl glucuronide concentrations in hair was investigated. For that purpose an optimized LC-MS/MS method was developed using a Hypercarb™ porous graphitic carbon (PGC) column and validated according to the guidelines of the German Society of Toxicological and Forensic Chemistry (GTFCh). Twenty-five hair samples of persons with known alcohol consumption behavior were investigated (21 positive samples and 4 blank samples). The hair samples were divided into two strands of hair and were analyzed after treatment with one out of four cleansing shampoos and without shampoo treatment. EtG concentrations in hair did not show any significant differences after a single application of the different cleansing shampoos. EtG was still detectable in all the positive hair samples without significant concentration change. These results clearly demonstrated that a single application of the tested cleansing shampoos did not remove EtG from hair and therefore had no influence on EtG concentration in analytical hair analysis. PMID:25151107

  17. The Image Quality of a Digital Chest X-Ray Radiography System: Comparison of Quantitative Image Quality Analysis and Radiologists' Visual Scoring

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Ji Ho [Dept. of Radiology Oncology, Yongsan Hospital, Pusan National University College of Medicine, Yongsan (Korea, Republic of); Chung, Myung Jin [Dept. of Radiology, Samsung Medical Center, Seoul (Korea, Republic of); Park, Darl; Kim, Won Taek; Kim, Yong Ho; Ki, Yong Kan; Kim, DFong Hyun; Lee, Ju Hee; Kim, Dong Won [Dept. of Radiology Oncology, Yongsan Hospital, Pusan National University College of Medicine, Yongsan (Korea, Republic of); Jeon, Ho Sang [Reserach Institue for Convergence of Biomedical Science and Technology, Yongsan Hospital, Pusan National University College of Medicine, Yongsan (Korea, Republic of)

    2011-11-15

    To evaluate the performance of imaging devices, which should be periodically monitored to maintain high quality images to the radiologists. Additionally, this evaluation may prevent patients from radiation over-exposure. The most suitable engineering standard for imaging performance evaluation of digital X-ray thoracic images was determined. IEC 62220-1 standards were used to evaluate the performance of the images. In succession, the visibilities of overall image, pneumothorax, and humerus head in anthropomorphic thoracic phantom images were used to evaluate the image qualities by radiologists. The rank correlation coefficient (p) of visual scoring by radiologists with system spatial resolution is not meaningful (p-value, p = 0.295), but is significant with image noise (p-value, p -0.9267). Finally, the noise equivalent quanta (NEQ) presents a high rank correlation for visual scoring of radiologists (p-value, p = 0.9320). Image quality evaluation of radiologists were mainly affected by imaging noise. Hence, the engineered standard for evaluating image noise is the most important index to effectively monitor the performance of X-ray images. Additionally, the NEQ can be used to evaluate the performance of radiographic systems, because it theoretically corresponds to the synthetic image quality of systems.

  18. Body condition score at calving affects systemic and hepatic transcriptome indicators of inflammation and nutrient metabolism in grazing dairy cows.

    Science.gov (United States)

    Akbar, H; Grala, T M; Vailati Riboni, M; Cardoso, F C; Verkerk, G; McGowan, J; Macdonald, K; Webster, J; Schutz, K; Meier, S; Matthews, L; Roche, J R; Loor, J J

    2015-02-01

    Calving body condition score (BCS) is an important determinant of early-lactation dry matter intake, milk yield, and disease incidence. The current study investigated the metabolic and molecular changes induced by the change in BCS. A group of cows of mixed age and breed were managed from the second half of the previous lactation to achieve mean group BCS (10-point scale) that were high (HBCS, 5.5; n=20), medium (MBCS, 4.5; n=18), or low (LBCS, 3.5; n=19). Blood was sampled at wk -4, -3, -2, 1, 3, 5, and 6 relative to parturition to measure biomarkers of energy balance, inflammation, and liver function. Liver was biopsied on wk 1, 3, and 5 relative to parturition, and 10 cows per BCS group were used for transcript profiling via quantitative PCR. Cows in HBCS and MBCS produced more milk and had greater concentrations of nonesterified fatty acids and β-hydroxybutyrate postpartum than LBCS. Peak concentrations of nonesterified fatty acids and β-hydroxybutyrate and greater hepatic triacylglycerol concentrations were recorded in HBCS at wk 3. Consistent with blood biomarkers, HBCS and MBCS had greater expression of genes associated with fatty acid oxidation (CPT1A, ACOX1), ketogenesis (HMGCS2), and hepatokines (FGF21, ANGPTL4), whereas HBCS had the lowest expression of APOB (lipoprotein transport). Greater expression during early lactation of BBOX1 in MBCS and LBCS suggested greater de novo carnitine synthesis. The greater BCS was associated with lower expression of growth hormone/insulin-like growth factor-1 signaling axis genes (GHR1A, IGF1, and IGFALS) and greater expression of gluconeogenic genes. These likely contributed to the higher milk production and greater gluconeogenesis. Despite greater serum haptoglobin around calving, cows in HBCS and MBCS had greater blood albumin. Cows in MBCS, however, had a higher albumin:globulin ratio, probably indicating a less pronounced inflammatory status and better liver function. The marked decrease in expression of NFKB1

  19. Application in the STRATHE trial of a score system to compare the efficacy and the tolerability of different therapeutic strategies in the management of hypertension

    Directory of Open Access Journals (Sweden)

    Bernard Waeber

    2008-02-01

    Full Text Available Bernard Waeber1, Jean-Jacques Mourad21Division de Physiopathologie Clinique, Centre Hospitalier Universitaire Vaudois et Université de Lausanne, Lausanne, Switzerland; 2Hôpital Avicienne, Bobigny, FranceAbstract: A score system integrating the evolution of efficacy and tolerability over time was applied to a subpopulation of the STRATHE trial, a trial performed according to a parallel group design, with a double-blind, random allocation to either a fixed-dose combination strategy (perindopril/indapamide 2 mg/0.625 mg, with the possibility to increase the dose to 3 mg/0.935 mg, and 4 mg/1.250 mg if needed, n = 118, a sequential monotherapy approach (atenolol 50 mg, followed by losartan 50 mg and amlodipine 5 mg if needed, n = 108, or a stepped-care strategy (valsartan 40 mg, followed by valsartan 80 mg and valsartan 80 mg+ hydrochlorothiazide 12.5 mg if needed, n = 103. The aim was to lower blood pressure below 140/90 mmHg within a 9-month period. The treatment could be adjusted after 3 and 6 months. Only patients in whom the study protocol was strictly applied were included in this analysis. At completion of the trial the total score averaged 13.1 ± 70.5 (mean ± SD using the fixed-dose combination strategy, compared with –7.2 ± 81.0 using the sequential monotherapy approach and –17.5 ± 76.4 using the stepped-care strategy. In conclusion, the use of a score system allows the comparison of antihypertensive therapeutic strategies, taking into account at the same time efficacy and tolerability. In the STRATHE trial the best results were observed with the fixed-dose combination containing low doses of an angiotensin enzyme converting inhibitor (perindopril and a diuretic (indapamide.Keywords: antihypertensive therapy, tolerability, antihypertensive efficacy, fixed-dose combination, sequential monotherapy, stepped-care treatment

  20. MR-sequences for prostate cancer diagnostics: validation based on the PI-RADS scoring system and targeted MR-guided in-bore biopsy

    Energy Technology Data Exchange (ETDEWEB)

    Schimmoeller, Lars; Quentin, Michael; Buchbender, Christian; Antoch, Gerald; Blondin, Dirk [University Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Dusseldorf (Germany); Arsov, Christian; Hiester, Andreas; Rabenalt, Robert; Albers, Peter [University Dusseldorf, Medical Faculty, Department of Urology, Dusseldorf (Germany)

    2014-10-15

    This study evaluated the accuracy of MR sequences [T2-, diffusion-weighted, and dynamic contrast-enhanced (T2WI, DWI, and DCE) imaging] at 3T, based on the European Society of Urogenital Radiology (ESUR) scoring system [Prostate Imaging Reporting and Data System (PI-RADS)] using MR-guided in-bore prostate biopsies as reference standard. In 235 consecutive patients [aged 65.7 ± 7.9 years; median prostate-specific antigen (PSA) 8 ng/ml] with multiparametric prostate MRI (mp-MRI), 566 lesions were scored according to PI-RADS. Histology of all lesions was obtained by targeted MR-guided in-bore biopsy. In 200 lesions, biopsy revealed prostate cancer (PCa). The area under the curve (AUC) for cancer detection was 0.70 (T2WI), 0.80 (DWI), and 0.74 (DCE). A combination of T2WI + DWI, T2WI + DCE, and DWI + DCE achieved an AUC of 0.81, 0.78, and 0.79. A summed PI-RADS score of T2WI + DWI + DCE achieved an AUC of 0.81. For higher grade PCa (primary Gleason pattern ≥ 4), the AUC was 0.85 for T2WI + DWI, 0.84 for T2WI + DCE, 0.86 for DWI + DCE, and 0.87 for T2WI + DWI + DCE. The AUC for T2WI + DWI + DCE for transitional-zone PCa was 0.73, and for the peripheral zone 0.88. Regarding higher-grade PCa, AUC for transitional-zone PCa was 0.88, and for peripheral zone 0.96. The combination of T2WI + DWI + DCE achieved the highest test accuracy, especially in patients with higher-grade PCa. The use of ≤2 MR sequences led to lower AUC in higher-grade and peripheral-zone cancers. (orig.)

  1. New Comprehensive Cytogenetic Scoring System for Primary Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia After MDS Derived From an International Database Merge

    Science.gov (United States)

    Schanz, Julie; Tüchler, Heinz; Solé, Francesc; Mallo, Mar; Luño, Elisa; Cervera, José; Granada, Isabel; Hildebrandt, Barbara; Slovak, Marilyn L.; Ohyashiki, Kazuma; Steidl, Christian; Fonatsch, Christa; Pfeilstöcker, Michael; Nösslinger, Thomas; Valent, Peter; Giagounidis, Aristoteles; Aul, Carlo; Lübbert, Michael; Stauder, Reinhard; Krieger, Otto; Garcia-Manero, Guillermo; Faderl, Stefan; Pierce, Sherry; Le Beau, Michelle M.; Bennett, John M.; Greenberg, Peter; Germing, Ulrich; Haase, Detlef

    2012-01-01

    Purpose The karyotype is a strong independent prognostic factor in myelodysplastic syndromes (MDS). Since the implementation of the International Prognostic Scoring System (IPSS) in 1997, knowledge concerning the prognostic impact of abnormalities has increased substantially. The present study proposes a new and comprehensive cytogenetic scoring system based on an international data collection of 2,902 patients. Patients and Methods Patients were included from the German-Austrian MDS Study Group (n = 1,193), the International MDS Risk Analysis Workshop (n = 816), the Spanish Hematological Cytogenetics Working Group (n = 849), and the International Working Group on MDS Cytogenetics (n = 44) databases. Patients with primary MDS and oligoblastic acute myeloid leukemia (AML) after MDS treated with supportive care only were evaluated for overall survival (OS) and AML evolution. Internal validation by bootstrap analysis and external validation in an independent patient cohort were performed to confirm the results. Results In total, 19 cytogenetic categories were defined, providing clear prognostic classification in 91% of all patients. The abnormalities were classified into five prognostic subgroups (P < .001): very good (median OS, 61 months; hazard ratio [HR], 0.5; n = 81); good (49 months; HR, 1.0 [reference category]; n = 1,809); intermediate (26 months; HR, 1.6; n = 529); poor (16 months; HR, 2.6; n = 148); and very poor (6 months; HR, 4.2; n = 187). The internal and external validations confirmed the results of the score. Conclusion In conclusion, these data should contribute to the ongoing efforts to update the IPSS by refining the cytogenetic risk categories. PMID:22331955

  2. An objective fluctuation score for Parkinson's disease.

    Directory of Open Access Journals (Sweden)

    Malcolm K Horne

    Full Text Available Establishing the presence and severity of fluctuations is important in managing Parkinson's Disease yet there is no reliable, objective means of doing this. In this study we have evaluated a Fluctuation Score derived from variations in dyskinesia and bradykinesia scores produced by an accelerometry based system.The Fluctuation Score was produced by summing the interquartile range of bradykinesia scores and dyskinesia scores produced every 2 minutes between 0900-1800 for at least 6 days by the accelerometry based system and expressing it as an algorithm.This Score could distinguish between fluctuating and non-fluctuating patients with high sensitivity and selectivity and was significant lower following activation of deep brain stimulators. The scores following deep brain stimulation lay in a band just above the score separating fluctuators from non-fluctuators, suggesting a range representing adequate motor control. When compared with control subjects the score of newly diagnosed patients show a loss of fluctuation with onset of PD. The score was calculated in subjects whose duration of disease was known and this showed that newly diagnosed patients soon develop higher scores which either fall under or within the range representing adequate motor control or instead go on to develop more severe fluctuations.The Fluctuation Score described here promises to be a useful tool for identifying patients whose fluctuations are progressing and may require therapeutic changes. It also shows promise as a useful research tool. Further studies are required to more accurately identify therapeutic targets and ranges.

  3. A practical MRI grading system for osteoarthritis of the knee: Association with Kellgren–Lawrence radiographic scores

    International Nuclear Information System (INIS)

    Purpose: To propose a reproducible and constant MR grading system for osteoarthritis of the knee joint that provides high interobserver and intraoberver agreement and that does not require complicated calculation procedures. Materials and methods: This retrospective study sample included 44 men and 65 women who underwent both MRI and plain radiography of the knee at our institution. All patients were older than 50 years of age (mean 57.7) and had clinically suspected osteoarthritis of the knee. The standard of 4 grades on the MR grade scale was based mainly on cartilage injury and additional findings. Kellgren–Lawrence grades were assessed for the same patient group. The relationship between the results was determined. Statistical analyses were performed including kappa statistics, categorical regression analysis and nonparametric correlation analysis. Results: The interobserver and intraoberver agreements between the two readers in the grading of osteoarthritis were found to be almost perfect. Interobserver and intraobserver agreements were slightly lower for the MR grading system than for the Kellgren–Lawrence grading scale. The correlation between the MR grade and Kellgren–Lawrence grade was very high and did not differ with patient age. The MR grades were highly correlated with the Kellgren–Lawrence grades and showed excellent interobserver and intraobserver agreements. Conclusion: This new MR grading system for osteoarthritis of the knee joint is reproducible and may be helpful for the grading of osteoarthritis of the knee without requiring reference to plain radiography

  4. A practical MRI grading system for osteoarthritis of the knee: Association with Kellgren–Lawrence radiographic scores

    Energy Technology Data Exchange (ETDEWEB)

    Park, Hee-Jin, E-mail: parkhiji@gmail.com [Department of Radiology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, #108 Pyung-dong, Jongno-gu, Seoul 110-746 (Korea, Republic of); Department of Radiology, Kangwon National University School of Medicine, Baengnyeong-ro 156, Chuncheon-Si, Gangwon-Do Kangwon National University Hospital 200-722 (Korea, Republic of); Kim, Sam Soo, E-mail: samskim@kangwon.ac.kr [Department of Radiology, Kangwon National University School of Medicine, Baengnyeong-ro 156, Chuncheon-Si, Gangwon-Do Kangwon National University Hospital 200-722 (Korea, Republic of); Lee, So-Yeon, E-mail: parkhiji@kwandong.ac.kr [Department of Radiology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, #108 Pyung-dong, Jongno-gu, Seoul 110-746 (Korea, Republic of); Park, Noh-Hyuck, E-mail: nhpark904@kwandong.ac.kr [Department of Radiology, Myongji Hospital, Kwandong University, College of Medicine, 697-24 Hwajung-dong, Dukyang-ku, Koyang, Kyunggi 412-270 (Korea, Republic of); Park, Ji-Yeon, E-mail: zzzz3@hanmail.net [Department of Radiology, Myongji Hospital, Kwandong University, College of Medicine, 697-24 Hwajung-dong, Dukyang-ku, Koyang, Kyunggi 412-270 (Korea, Republic of); Choi, Yoon-Jung, E-mail: yoonchoi99@gmail.com [Department of Radiology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, #108 Pyung-dong, Jongno-gu, Seoul 110-746 (Korea, Republic of); Jeon, Hyun-Jun, E-mail: ostrich-13@hanmail.net [Department of Occupational Medicine, Dongsan Medical Center, Keimyung University School of Medicine, 194 Dongsan-Dong, Jung-ku, Taegu (Korea, Republic of)

    2013-01-15

    Purpose: To propose a reproducible and constant MR grading system for osteoarthritis of the knee joint that provides high interobserver and intraoberver agreement and that does not require complicated calculation procedures. Materials and methods: This retrospective study sample included 44 men and 65 women who underwent both MRI and plain radiography of the knee at our institution. All patients were older than 50 years of age (mean 57.7) and had clinically suspected osteoarthritis of the knee. The standard of 4 grades on the MR grade scale was based mainly on cartilage injury and additional findings. Kellgren–Lawrence grades were assessed for the same patient group. The relationship between the results was determined. Statistical analyses were performed including kappa statistics, categorical regression analysis and nonparametric correlation analysis. Results: The interobserver and intraoberver agreements between the two readers in the grading of osteoarthritis were found to be almost perfect. Interobserver and intraobserver agreements were slightly lower for the MR grading system than for the Kellgren–Lawrence grading scale. The correlation between the MR grade and Kellgren–Lawrence grade was very high and did not differ with patient age. The MR grades were highly correlated with the Kellgren–Lawrence grades and showed excellent interobserver and intraobserver agreements. Conclusion: This new MR grading system for osteoarthritis of the knee joint is reproducible and may be helpful for the grading of osteoarthritis of the knee without requiring reference to plain radiography.

  5. Application of string similarity in automatic scoring system%字符串相似度在自动评分系统中的应用

    Institute of Scientific and Technical Information of China (English)

    杜利峰; 牛永洁

    2011-01-01

    In the automatic scoring system of programming language,gapfilling test of programming always used exact string matching method,and automatic scoring of programming question has always been a difficulty. By analysing the characteristics of two kinds of questions and advantages and disadvantages of current method,string similarity algorithm was used,and the overall flow figure of the marking process was given too.The actual usc shows that this method is a good supplement to the current using method, which makes the scoring process more objective and fair. It can reduce the works of teachers,improve the teaching efficiency,and it is worth to promote.%在对编程语言类的自动评分系统中,程序设计类型的填空题大多采用字符串精确匹配的方法,而编程题的自动评分是一个难点.在分析两类题型的特点及目前采用的评测方法的优缺点的基础上,提出使用字符串相似度算法对程序设计题进行评判,并给出了评分过程的整体流程图.经过实际的使用,证明该方法是目前采用方法的一个很好补充,使评分的过程更加客观、公正,能够减少教师的工作量,提高教学工作效率,值得推广.

  6. The ability of two scoring systems to predict in-hospital mortality of patients with moderate and severe traumatic brain injuries in a Moroccan intensive care unit

    Directory of Open Access Journals (Sweden)

    Hicham Nejmi

    2014-01-01

    Full Text Available Aim of Study: We aim to assess and to compare the predicting power for in-hospital mortality (IHM of the Acute Physiology and Chronic Health Evaluation-II (APACHE-II and the Simplified Acute Physiology Score-II (SAPS-II for traumatic brain injury (TBI. Patients and Methods: This retrospective cohort study was conducted during a period of 2 years and 9 months in a Moroccan intensive care unit. Data were collected during the first 24 h of each admission. The clinical and laboratory parameters were analyzed and used as per each scoring system to calculate the scores. Univariate and multivariate analyses through regression logistic models were performed, to predict IHM after moderate and severe TBIs. Areas under the receiver operating characteristic curves (AUROC, specificities and sensitivities were determined and also compared. Results: A total of 225 patients were enrolled. The observed IHM was 51.5%. The univariate analysis showed that the initial Glasgow coma scale (GCS was lower in nonsurviving patients (mean GCS = 6 than the survivors (mean GCS = 9 with a statistically significant difference (P = 0.0024. The APACHE-II and the SAPS-II of the nonsurviving patients were higher than those of the survivors (respectively 20.4 ± 6.8 and 31.2 ± 13.6 for nonsurvivors vs. 15.7 ± 5.4 and 22.7 ± 10.3 for survivors with a statistically significant difference (P = 0.0032 for APACHE-II and P = 0.0045 for SAPS-II. Multivariate analysis: APACHE-II was superior for predicting IHM (AUROC = 0.92. Conclusion: The APACHE-II is an interesting tool to predict IHM of head injury patients. This is particularly relevant in Morocco, where TBI is a greater public health problem than in many other countries.

  7. The Landing Error Scoring System as a Screening Tool for an Anterior Cruciate Ligament Injury–Prevention Program in Elite-Youth Soccer Athletes

    Science.gov (United States)

    Padua, Darin A.; DiStefano, Lindsay J.; Beutler, Anthony I.; de la Motte, Sarah J.; DiStefano, Michael J.; Marshall, Steven W.

    2015-01-01

    Context Identifying neuromuscular screening factors for anterior cruciate ligament (ACL) injury is a critical step toward large-scale deployment of effective ACL injury-prevention programs. The Landing Error Scoring System (LESS) is a valid and reliable clinical assessment of jump-landing biomechanics. Objective To investigate the ability of the LESS to identify individuals at risk for ACL injury in an elite-youth soccer population. Design Cohort study. Setting Field-based functional movement screening performed at soccer practice facilities. Patients or Other Participants A total of 829 elite-youth soccer athletes (348 boys, 481 girls; age = 13.9 ± 1.8 years, age range = 11 to 18 years), of whom 25% (n = 207) were less than 13 years of age. Intervention(s) Baseline preseason testing for all participants consisted of a jump-landing task (3 trials). Participants were followed prospectively throughout their soccer seasons for diagnosis of ACL injuries (1217 athlete-seasons of follow-up). Main Outcome Measure(s) Landings were scored for “errors” in technique using the LESS. We used receiver operator characteristic curves to determine a cutpoint on the LESS. Sensitivity and specificity of the LESS in predicting ACL injury were assessed. Results Seven participants sustained ACL injuries during the follow-up period; the mechanism of injury was noncontact or indirect contact for all injuries. Uninjured participants had lower LESS scores (4.43 ± 1.71) than injured participants (6.24 ± 1.75; t1215 = −2.784, P = .005). The receiver operator characteristic curve analyses suggested that 5 was the optimal cutpoint for the LESS, generating a sensitivity of 86% and a specificity of 64%. Conclusions Despite sample-size limitations, the LESS showed potential as a screening tool to determine ACL injury risk in elite-youth soccer athletes. PMID:25811846

  8. Primary radiotherapy or postoperative radiotherapy in patients with head and neck cancer. Comparative analysis of inflammation-based prognostic scoring systems

    Energy Technology Data Exchange (ETDEWEB)

    Selzer, Edgar; Grah, Anja [Medical University of Vienna, Department of Radiotherapy, Vienna (Austria); Heiduschka, Gregor; Thurnher, Dietmar [Medical University of Vienna, Otorhinolaryngology - Head and Neck Surgery, Vienna (Austria); Kornek, Gabriela [Medical University of Vienna, Medicine I - Division of Clinical Oncology, Vienna (Austria)

    2015-01-13

    Inflammation-based scoring systems have potential value in evaluating the prognosis of cancer patients; however, detailed comparative analyses in well-characterized head and neck cancer patient collectives are missing. We analyzed overall survival (OS) in locally advanced head and neck cancer patients who were treated with curative intent by primary radiotherapy (RT) alone, by RT in combination with cetuximab (RIT) or with cisplatin (RCHT), and by primary surgery followed by postoperative radiotherapy (PORT). The primary RT collective (N = 170) was analyzed separately from the surgery plus RT group (N = 148). OS was estimated using the Kaplan-Meyer method. Cox proportional-hazard regression models were applied to compare the risk of death among patients stratified according to risk factors and the inflammation-based Glasgow Prognostic Score (GPS), the modified GPS (mGPS), the neutrophil-lymphocyte ratio (NLR), the platelet-lymphocyte ratio (PLR), and the prognostic index (PI). A prognostic relevance of the scoring systems for OS was observed in the primarily irradiated, but not in the PORT collective. OS was 35.5, 18.8, and 15.4 months, respectively, according to GPS 0, 1, and 2. OS according to mGPS 0-2 was identical. The PLR scoring system was not of prognostic relevance, while OS was 27.3 months in the NLR 0 group and 17.3 months in the NLR 1 group. OS was 35.5 months in PI 0, 16.1 months in PI 1, and 22.6 months in PI 2. GPS/mGPS scoring systems are able to discriminate between three risk groups in primarily, but not postoperatively irradiated locally advanced head and neck cancer patients. (orig.) [German] Entzuendungsbasierte Bewertungssysteme haben eine potenzielle Bedeutung fuer die Beurteilung der Prognose von Krebspatienten. Derzeit fehlen jedoch ausreichend detailliert durchgefuehrte Analysen in Kollektiven von Patienten mit Kopf-Hals-Tumoren. Untersucht wurde das Gesamtueberleben (''overall survival'', OS) von Patienten mit lokal

  9. Home Energy Score

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-12-16

    The Home Energy Score allows a homeowner to compare her or his home's energy consumption to that of other homes, similar to a vehicle's mile-per-gallon rating. A home energy assessor will collect energy information during a brief home walk-through and then score that home on a scale of 1 to 10.

  10. SCORE - A DESCRIPTION.

    Science.gov (United States)

    SLACK, CHARLES W.

    REINFORCEMENT AND ROLE-REVERSAL TECHNIQUES ARE USED IN THE SCORE PROJECT, A LOW-COST PROGRAM OF DELINQUENCY PREVENTION FOR HARD-CORE TEENAGE STREET CORNER BOYS. COMMITTED TO THE BELIEF THAT THE BOYS HAVE THE POTENTIAL FOR ETHICAL BEHAVIOR, THE SCORE WORKER FOLLOWS B.F. SKINNER'S THEORY OF OPERANT CONDITIONING AND REINFORCES THE DELINQUENT'S GOOD…

  11. SAT Scores, 2013-14: Wake County Public School System (WCPSS). Measuring Up. D&A Report No. 14.14

    Science.gov (United States)

    Gilleland, Kevin; Muli, Juliana

    2014-01-01

    The SAT is a national college entrance examination offered by the College Board and consists of three parts: Mathematics, Critical Reading, and Writing. The top score for each part is 800, for a total possible score of 2400. Colleges use SAT scores, in conjunction with other tools, to measure students' potential for success at the postsecondary…

  12. The Group Decision Support System to Evaluate the ICT Project Performance Using the Hybrid Method of AHP, TOPSIS and Copeland Score

    Directory of Open Access Journals (Sweden)

    Herri Setiawan

    2016-04-01

    Full Text Available This paper proposed a concept of the Group Decision Support System (GDSS to evaluate the performance of Information and Communications Technology (ICT Projects in Indonesian regional government agencies to overcome any possible inconsistencies which may occur in a decision-making process. By considering the aspect of the applicable legislation, decision makers involved to provide an assessment and evaluation of the ICT project implementation in regional government agencies consisted of Executing Parties of Government Institutions, ICT Management Work Units, Business Process Owner Units, and Society, represented by DPRD (Regional People’s Representative Assembly. The contributions of those decision makers in the said model were in the form of preferences to evaluate the ICT project-related alternatives based on the predetermined criteria for the method of Multiple Criteria Decision Making (MCDM. This research presented a GDSS framework integrating the Methods of Analytic Hierarchy Process (AHP, Technique for Order Preference by Similarity to Ideal Solution (TOPSIS and Copeland Score. The AHP method was used to generate values for the criteria used as input in the calculation process of the TOPSIS method. Results of the TOPSIS calculation generated a project rank indicated by each decision maker, and to combine the different preferences of these decision makers, the Copeland Score method was used as one of the voting methods to determine the best project rank of all the ranks indicated by the desicion makers.

  13. In Vitro Testing of Scaffolds for Mesenchymal Stem Cell-Based Meniscus Tissue Engineering—Introducing a New Biocompatibility Scoring System

    Directory of Open Access Journals (Sweden)

    Felix P. Achatz

    2016-04-01

    Full Text Available A combination of mesenchymal stem cells (MSCs and scaffolds seems to be a promising approach for meniscus repair. To facilitate the search for an appropriate scaffold material a reliable and objective in vitro testing system is essential. This paper introduces a new scoring for this purpose and analyzes a hyaluronic acid (HA gelatin composite scaffold and a polyurethane scaffold in combination with MSCs for tissue engineering of meniscus. The pore quality and interconnectivity of pores of a HA gelatin composite scaffold and a polyurethane scaffold were analyzed by surface photography and Berliner-Blau-BSA-solution vacuum filling. Further the two scaffold materials were vacuum-filled with human MSCs and analyzed by histology and immunohistochemistry after 21 days in chondrogenic media to determine cell distribution and cell survival as well as proteoglycan production, collagen type I and II content. The polyurethane scaffold showed better results than the hyaluronic acid gelatin composite scaffold, with signs of central necrosis in the HA gelatin composite scaffolds. The polyurethane scaffold showed good porosity, excellent pore interconnectivity, good cell distribution and cell survival, as well as an extensive content of proteoglycans and collagen type II. The polyurethane scaffold seems to be a promising biomaterial for a mesenchymal stem cell-based tissue engineering approach for meniscal repair. The new score could be applied as a new standard for in vitro scaffold testing.

  14. Human tooth wear in the past and the present: tribological mechanisms, scoring systems, dental and skeletal compensations.

    Science.gov (United States)

    d'Incau, Emmanuel; Couture, Christine; Maureille, Bruno

    2012-03-01

    This review of human tooth wear describes the fundamental mechanisms underlying this process. Using the tribological approach they can be systematised and this in turn aids our understanding of them. In past populations wear was ubiquitous, intense, abrasive and physiological as it was related to their food and their technologies. In these populations, it affected the proximal surfaces, and the occlusal surfaces which modified the occlusal plane profoundly. To categorise this wear many different classification systems are used, from which we can determine diet, cultural changes and the age at death of individuals. They also illustrate the evolution of certain functional dental and skeletal compensations in the masticatory apparatus such as continuous dental eruption, mesial drift of the arches and incisor lingual tipping which can then be monitored. These physiological adaptations related mainly to function and ontogenesis can also be found in present-day populations where wear is moderate, although they are much less obtrusive. Apart from certain pathological cases associated with a specific parafunction, iatrogenic tooth brushing or an eating disorder and encouraged by an acid environment, they are the result of a physiological process that should not be halted. To ensure this, it is essential to prevent lesions related to tooth wear, to detect them early and establish a reliable diagnosis. Types of tooth wear that had remained unchanged since the origin of humanity have undergone profound changes in a very short space of time. Today's tribochemical pathological model has replaced the abrasive physiological model of the past. PMID:21920497

  15. The Association among Antioxidant Enzymes, Autoantibodies, and Disease Severity Score in Systemic Lupus Erythematosus: Comparison of Neuropsychiatric and Nonneuropsychiatric Groups

    Directory of Open Access Journals (Sweden)

    Yu-Jih Su

    2014-01-01

    Full Text Available Background. Antioxidative capacity plays an important role in the severity of systemic lupus erythematosus (SLE, which is characterized by autoantibodies. This study aimed to determine the relationship among autoantibody titers, antioxidative stress reserve, and severity of SLE. Methods. The autoantibody titers, clinical markers, antioxidant enzyme levels, and disease activity index (SLEDAI-2k of 32 SLE patients and 16 healthy controls were compared. We also compared both the neuropsychiatric (NPSLE and nonneuropsychiatric (non-NPSLE groups. Results. Superoxide dismutase in red blood cells was significantly lower in the SLE than in the control group. CRP levels are significant higher in SLE patients than in control group (P=0.034. Among the autoantibodies, anti-U1RNP P=0.008, a-Sm P=0.027, and anti-ribosomal p P=0.028 significantly negatively correlated with glutathione levels. There has no significant correlation between SLE disease activity indexes (SLEDAI and levels of C3, C4, and antioxidant enzymes. Conclusions. Erythrocyte superoxide dismutase is significantly lower in both NPSLE and non-NPSLE groups. SLE patients have both higher CRP and autoantibodies level and decreased superoxide dismutase level than the healthy control group.

  16. Reporting Valid and Reliable Overall Scores and Domain Scores

    Science.gov (United States)

    Yao, Lihua

    2010-01-01

    In educational assessment, overall scores obtained by simply averaging a number of domain scores are sometimes reported. However, simply averaging the domain scores ignores the fact that different domains have different score points, that scores from those domains are related, and that at different score points the relationship between overall…

  17. The Bandim tuberculosis score

    DEFF Research Database (Denmark)

    Rudolf, Frauke; Joaquim, Luis Carlos; Vieira, Cesaltina;

    2013-01-01

    Background: This study was carried out in Guinea-Bissau ’ s capital Bissau among inpatients and outpatients attending for tuberculosis (TB) treatment within the study area of the Bandim Health Project, a Health and Demographic Surveillance Site. Our aim was to assess the variability between 2...... physicians in performing the Bandim tuberculosis score (TBscore), a clinical severity score for pulmonary TB (PTB), and to compare it to the Karnofsky performance score (KPS). Method : From December 2008 to July 2009 we assessed the TBscore and the KPS of 100 PTB patients at inclusion in the TB cohort and...

  18. Credit Scoring Modeling

    Directory of Open Access Journals (Sweden)

    Siana Halim

    2014-01-01

    Full Text Available It is generally easier to predict defaults accurately if a large data set (including defaults is available for estimating the prediction model. This puts not only small banks, which tend to have smaller data sets, at disadvantage. It can also pose a problem for large banks that began to collect their own historical data only recently, or banks that recently introduced a new rating system. We used a Bayesian methodology that enables banks with small data sets to improve their default probability. Another advantage of the Bayesian method is that it provides a natural way for dealing with structural differences between a bank’s internal data and additional, external data. In practice, the true scoring function may differ across the data sets, the small internal data set may contain information that is missing in the larger external data set, or the variables in the two data sets are not exactly the same but related. Bayesian method can handle such kind of problem.

  19. Trends in the Use of Nephron-Sparing Surgery over 7 Years: An Analysis Using the R.E.N.A.L. Nephrometry Scoring System.

    Directory of Open Access Journals (Sweden)

    Seung Jea Shin

    Full Text Available To analyze trends in the use of partial nephrectomy, we evaluated which individual factors of renal nephrometry score (RNS influenced the operative approach bi-annually from 2008 to 2014.We performed a retrospective review of renal cell carcinoma treated by surgery in 2008, 2010, 2012, and 2014. The complexity of renal masses was measured using the R.E.N.A.L. nephrometry scoring system with CT or MRI. Group comparison in terms of operation year and surgical type (partial nephrectomy versus radical nephrectomy was performed. We developed a nomogram to quantitate the likelihood of selecting partial nephrectomy over radical nephrectomy.A total of 1106 cases (237 in 2008, 225 in 2010, 292 in 2012, and 352 in 2014 were available for the study. Over the study period, the proportion of partial nephrectomies performed increased steadily from 21.5% in 2008 to 66.5% in 2014 (p < 0.05. Furthermore, use of partial nephrectomy increased steadily in all RNS complexity groups (low, moderate, and high (p < 0.05. In the analysis of individual components of RNS, values of the R and N components increased statistically by year in the partial nephrectomy group (p < 0.05. Average AUC was 0.920.The proportion of partial nephrectomies performed sharply increased over the study period. Additionally, over the study period, more partial nephrectomies were performed for renal masses of larger size and closer to the collecting system and main renal vessels. A nomogram developed based on this recent data set provides significant predictive value for surgical decision making.

  20. Pneumonia severity scores in resource poor settings

    Directory of Open Access Journals (Sweden)

    Jamie Rylance

    2014-06-01

    Full Text Available Clinical prognostic scores are increasingly used to streamline care in well-resourced settings. The potential benefits of identifying patients at risk of clinical deterioration and poor outcome, delivering appropriate higher level clinical care, and increasing efficiency are clear. In this focused review, we examine the use and applicability of severity scores applied to patients with community acquired pneumonia in resource poor settings. We challenge clinical researchers working in such systems to consider the generalisability of existing severity scores in their populations, and where performance of scores is suboptimal, to promote efforts to develop and validate new tools for the benefit of patients and healthcare systems.

  1. Lying times of lactating cows on dairy farms with automatic milking systems and the relation to lameness, leg lesions, and body condition score.

    Science.gov (United States)

    Westin, R; Vaughan, A; de Passillé, A M; DeVries, T J; Pajor, E A; Pellerin, D; Siegford, J M; Vasseur, E; Rushen, J

    2016-01-01

    Lying down and resting are important for optimal cow health, welfare, and production. In comparison with free stall farms with a milking parlor, farms with automated milking systems (AMS) may place less constraint on how long cows can lie down. However, few studies report lying times on AMS farms. The aims of this study were to describe the variation in lying times of dairy cows in AMS farms and to understand how much of the variation in individual lying times is related to cow-level factors, including lameness, the presence of hock and knee lesions, and body condition score (BCS). We visited 36 farms in Canada (Quebec: n = 10; Ontario: n = 10; British Columbia: n = 4; and Alberta: n = 5), and the United States (Michigan: n = 7). Gait scores, presence of hock and knee lesions, and BCS were recorded for 40 Holstein cows from each herd. Parity and days in milk were retrieved from farm records. Lying time was recorded across 4d using accelerometers (n = 1,377). Multivariable analysis was performed. Of scored cows, 15.1% were lame (i.e., obviously limping; 203 of 1,348 cows). Knee lesions were found in 27.1% (340 of 1,256 cows) and hock lesions were found in 30.8% (421 of 1,366 cows) of the animals. Daily lying time varied among cows. Cows spent a median duration of 11.4 h/d lying down (25th-75th percentile = 9.7-12.9 h), with a lying bout frequency of 9.5 bouts/d (25th-75th percentile = 7.5-12 bouts/d) and a median bout duration of 71 min (25th-75th percentile = 58-87 min/bout). Lameness was associated with cows lying down for 0.6 h/d longer in fewer, longer bouts. Increased lying time was also associated with increased parity, later stage of lactation and higher BCS. Older cows (parity ≥ 3) spent about 0.5 h/d more lying down compared with parity 1 cows, and cows with BCS ≥ 3.5 lay down on average 1 h/d longer than cows with BCS ≤ 2.25. Hock lesions were associated with shorter lying times in univariable models, but no associations were found in the

  2. Evaluation of stone-free rate using Guy's Stone Score and assessment of complications using modified Clavien grading system for percutaneous nephro-lithotomy.

    Science.gov (United States)

    Sinha, Rajan Kumar; Mukherjee, Subhabrata; Jindal, Tarun; Sharma, Pramod Kumar; Saha, Barun; Mitra, Nilanjan; Kumar, Jay; Mukhopadhyay, Chandranath; Ghosh, Nabankur; Kamal, Mir Reza; Mandal, Soumendra Nath; Karmakar, Dilip

    2015-08-01

    To prospectively evaluate the ability of Guy's Stone Score (GSS) in predicting stone clearance rate and complication rate (by modified Clavien grade) for renal stones treated by percutaneous nephrolithotomy (PNL). From January 2013 to June 2014, a total of 142 patients undergoing PNL were evaluated prospectively. Patients with co-morbidities like hypertension, diabetes, renal failure were excluded from the study. All patients were classified according to GSS based on the findings of pre-operative intravenous urography (IVU) and per-operative retrograde pyelography (RGP). All PNL procedures were done by standard technique in prone position and success was defined as no residual stone visible on X-ray KUB done on the third postoperative day. Complications were classified according to modified Clavien grading system. The initial stone clearance rate was 71.1% and overall final stone clearance rate was 90.14%. The complication rate according to Clavien grading system was 40.1%. The final stone clearance rates were 93.9, 85.71, 90.47, and 77.77% in GSS I, II, III, and IV, respectively (p0.05, respectively). The Clavien complication rates were 23, 61, 52, and 77.7% in GSS I, II, III, and IV, respectively (p<0.001). The GSS is a simple and easily reproducible system to preoperatively predict stone-free rate and perioperative complication rate. It helps in better patient counseling preoperatively. PMID:25850962

  3. Programming Interactive Music Scores with INScore

    OpenAIRE

    Fober, Dominique; Letz, Stéphane; Orlarey, Yann; Bevilacqua, Frédéric

    2013-01-01

    International audience INScore is an environment for the design of interactive music scores that includes an original event-based interaction system and a scripting language for associating arbitrary messages to these events. We extended the previous version by supporting scripting languages offering a great flexibility in the description of scores and in the interactions with scores. The textual format is directly derived from the OSC message format that was defined in the original INScor...

  4. Why Does the “Sinner” Act Prosocially? The Mediating Role of Guilt and the Moderating Role of Moral Identity in Motivating Moral Cleansing

    Science.gov (United States)

    Ding, Wan; Xie, Ruibo; Sun, Binghai; Li, Weijian; Wang, Duo; Zhen, Rui

    2016-01-01

    Numerous studies have found that people tend to commit prosocial acts subsequent to previous immoral acts, as a response to the latter. This phenomenon is called moral cleansing or moral compensation. However, the specific mechanism how previous immoral acts motivate moral compensatory behaviors is still not fully understood. This study aimed to examine the roles of guilt and moral identity in the relation between previous immoral acts and subsequent prosocial behaviors to clarify the mechanism. Based on the extant research, the current study proposed a moderated mediation model to illustrate the process of moral cleansing. Specifically, a previous immoral act motivates guilt, which further leads to subsequent prosocial behaviors, while moral identity facilitates this process. The participants were primed by a recalling task (immoral act vs. a neutral event). The results support the hypothesized model and provide a framework that explains moral cleansing by integrating the roles of guilt and moral identity. These findings highlight the dynamic nature of people’s morality with regard to how people adapt moral behaviors to protect their moral self-image.

  5. The Bender Gestalt Test with the Human Figure Drawing Test for Young School Children. A Manual for Use with the Koppitz Scoring System.

    Science.gov (United States)

    Koppitz, Elizabeth Munsterberg

    Presented is a manual for scoring the Bender Gestalt Test and the Human Figure Drawing Test for screening and diagnostic uses with emotionally disturbed, brain damaged, or perceptually handicapped 5- to 11-year-old children. Given are suggestions for administering and scoring the Bender test which examines distortion of shape, rotation,…

  6. Usefulness of Cardiac MetaIodobenzylguanidine Imaging to Improve Prognostic Power of the Model for End-Stage Liver Disease Scoring System in Patients With Mild-to-Moderate Chronic Heart Failure.

    Science.gov (United States)

    Hakui, Hideyuki; Yamada, Takahisa; Tamaki, Shunsuke; Morita, Takashi; Furukawa, Yoshio; Iwasaki, Yusuke; Kawasaki, Masato; Kikuchi, Atsushi; Kondo, Takumi; Ishimi, Masashi; Sato, Yoshihiro; Seo, Masahiro; Ozaki, Tatsuhisa; Ikeda, Iyo; Fukuhara, Eiji; Sakata, Yasushi; Fukunami, Masatake

    2016-06-15

    Liver dysfunction has a prognostic impact on the outcomes of patients with advanced heart failure (HF). The model for end-stage liver disease (MELD) score is a robust system for rating liver dysfunction, and a high score has been shown to be associated with a poor prognosis in ambulatory patients with HF. In addition, cardiac metaiodobenzylguanidine (MIBG) imaging provides prognostic information in patients with chronic HF (CHF). However, the long-term predictive value of combining the MELD score and cardiac MIBG imaging in patients with CHF has not been elucidated. To prospectively investigate whether cardiac MIBG imaging provides additional prognostic value to the MELD score in patients with mild-to-moderate CHF, we studied 109 CHF outpatients (New York Heart Association: 2.0 ± 0.6) with left ventricular ejection fraction 27%) had a significantly greater risk of CD than those with normal WR in both those with high MELD scores (≥10; hazard ratio 4.0 [1.2 to 13.6]) and with low MELD scores (<10; hazard ratio 6.4 [1.7 to 23.2]). In conclusion, cardiac MIBG imaging would provide additional prognostic information to the MELD score in patients with mild-to-moderate CHF. PMID:27237625

  7. Instant MuseScore

    CERN Document Server

    Shinn, Maxwell

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. Instant MuseScore is written in an easy-to follow format, packed with illustrations that will help you get started with this music composition software.This book is for musicians who would like to learn how to notate music digitally with MuseScore. Readers should already have some knowledge about musical terminology; however, no prior experience with music notation software is necessary.

  8. Validation of cytogenetic risk groups according to International Prognostic Scoring Systems by peripheral blood CD34+FISH: results from a German diagnostic study in comparison with an international control group

    Science.gov (United States)

    Braulke, Friederike; Platzbecker, Uwe; Müller-Thomas, Catharina; Götze, Katharina; Germing, Ulrich; Brümmendorf, Tim H.; Nolte, Florian; Hofmann, Wolf-Karsten; Giagounidis, Aristoteles A. N.; Lübbert, Michael; Greenberg, Peter L.; Bennett, John M.; Solé, Francesc; Mallo, Mar; Slovak, Marilyn L.; Ohyashiki, Kazuma; Le Beau, Michelle M.; Tüchler, Heinz; Pfeilstöcker, Michael; Nösslinger, Thomas; Hildebrandt, Barbara; Shirneshan, Katayoon; Aul, Carlo; Stauder, Reinhard; Sperr, Wolfgang R.; Valent, Peter; Fonatsch, Christa; Trümper, Lorenz; Haase, Detlef; Schanz, Julie

    2015-01-01

    International Prognostic Scoring Systems are used to determine the individual risk profile of myelodysplastic syndrome patients. For the assessment of International Prognostic Scoring Systems, an adequate chromosome banding analysis of the bone marrow is essential. Cytogenetic information is not available for a substantial number of patients (5%–20%) with dry marrow or an insufficient number of metaphase cells. For these patients, a valid risk classification is impossible. In the study presented here, the International Prognostic Scoring Systems were validated based on fluorescence in situ hybridization analyses using extended probe panels applied to cluster of differentiation 34 positive (CD34+) peripheral blood cells of 328 MDS patients of our prospective multicenter German diagnostic study and compared to chromosome banding results of 2902 previously published patients with myelodysplastic syndromes. For cytogenetic risk classification by fluorescence in situ hybridization analyses of CD34+ peripheral blood cells, the groups differed significantly for overall and leukemia-free survival by uni- and multivariate analyses without discrepancies between treated and untreated patients. Including cytogenetic data of fluorescence in situ hybridization analyses of peripheral CD34+ blood cells (instead of bone marrow banding analysis) into the complete International Prognostic Scoring System assessment, the prognostic risk groups separated significantly for overall and leukemia-free survival. Our data show that a reliable stratification to the risk groups of the International Prognostic Scoring Systems is possible from peripheral blood in patients with missing chromosome banding analysis by using a comprehensive probe panel (clinicaltrials.gov identifier:01355913). PMID:25344522

  9. 24 CFR 902.45 - Management operations scoring and thresholds.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Management operations scoring and... URBAN DEVELOPMENT PUBLIC HOUSING ASSESSMENT SYSTEM PHAS Indicator #3: Management Operations § 902.45 Management operations scoring and thresholds. (a) Scoring. The Management Operations Indicator score...

  10. Tensorial Orientation Scores

    NARCIS (Netherlands)

    van de Gronde, Jasper J.; Azzopardi, George; Petkov, Nicolai

    2015-01-01

    Orientation scores are representations of images built using filters that only select on orientation (and not on the magnitude of the frequency). Importantly, they allow (easy) reconstruction, making them ideal for use in a filtering pipeline. Traditionally a specific set of orientations has to be c

  11. Developing Scoring Algorithms

    Science.gov (United States)

    We developed scoring procedures to convert screener responses to estimates of individual dietary intake for fruits and vegetables, dairy, added sugars, whole grains, fiber, and calcium using the What We Eat in America 24-hour dietary recall data from the 2003-2006 NHANES.

  12. The lod score method.

    Science.gov (United States)

    Rice, J P; Saccone, N L; Corbett, J

    2001-01-01

    The lod score method originated in a seminal article by Newton Morton in 1955. The method is broadly concerned with issues of power and the posterior probability of linkage, ensuring that a reported linkage has a high probability of being a true linkage. In addition, the method is sequential, so that pedigrees or lod curves may be combined from published reports to pool data for analysis. This approach has been remarkably successful for 50 years in identifying disease genes for Mendelian disorders. After discussing these issues, we consider the situation for complex disorders, where the maximum lod score (MLS) statistic shares some of the advantages of the traditional lod score approach but is limited by unknown power and the lack of sharing of the primary data needed to optimally combine analytic results. We may still learn from the lod score method as we explore new methods in molecular biology and genetic analysis to utilize the complete human DNA sequence and the cataloging of all human genes.

  13. Design on a Student Score Management System Based on ASP.NET%基于ASP.NET学生成绩管理系统的设计与实现

    Institute of Scientific and Technical Information of China (English)

    俞露

    2013-01-01

    该文将学生成绩管理系统划分为三个功能模块:管理员管理模块,教师成绩录入模块,学生成绩查询模块.并采用三层架构来设计系统.在SQL server Management 2005中通过新建查询的方式建立数据库,在Visual studio 2010环境下,编写C#语言加以实现.%This paper divides student score management system into three independent functional modules:administrator manage?ment module, teacher input score module, and student query score module,and uses three-tier architecture to design system. In SQL server Management 2005,this paper creates database by newing query , in the Visual Studio 2010 environment, this paper us?es C# language to achieve system functions .

  14. Endoscopic scoring of late gastrointestinal mucosal damage after adjuvant radiochemotherapy

    Institute of Scientific and Technical Information of China (English)

    Resat Dabak; Oya Uygur-Bayramicli; Cengiz Gemici; Dilek Yavuzer; Mehmet Sargin; Mehmet Yildirim

    2006-01-01

    AIM: To evaluate late effects of chemoradiation on gastrointestinal mucosa with an endoscopic scoring system and compare it to a clinical scoring system.METHODS: Twenty-four patients going to receive chemoradiation after gastric surgery underwent endoscopy four wk after surgery and one year after the chemoradiation finished. Upper gastrointestinal findings were recorded according to a system proposed by World Organisation for Digestive Endoscopy (OMED) and clinical scoring was done with RTOG-EORTC radiation morbidity scoring systems.RESULTS: There was no significant endoscopic difference in gastric and intestinal mucosa after chemoradiation (P > 0.05) and there was no association between endoscopic scores and clinical scores.Endoscopic changes were minimal.CONCLUSION: Late effects after chemoradiation in operated patients with gastric cancers can be evaluated with an endoscopic scoring system objectively and this system is superior to clinical scoring systems.

  15. Is scoring system of computed tomography based metric parameters can accurately predicts shock wave lithotripsy stone-free rates and aid in the development of treatment strategies?

    Directory of Open Access Journals (Sweden)

    Yasser ALI Badran

    2016-01-01

    Conclusion: Stone size, stone density (HU, and SSD is simple to calculate and can be reported by radiologists to applying combined score help to augment predictive power of SWL, reduce cost, and improving of treatment strategies.

  16. Implementation of flushing tanks in combined sewer networks to comply with optimal self-cleansing properties

    OpenAIRE

    Haji Seyed Mohammad Shirazi, Reza; Bouteligier, Raf; Willems, Patrick; Berlamont, Jean

    2009-01-01

    Combined sewer networks are designed to collect and transport the aqueous and solid wastes originating from domestic, industrial and catchment surfaces for treatment and disposal. One of the problems that arise is sedimentation of the particles within the collected water while flowing throughout such networks. In fact, many sewer pipes in combined sewer systems experience considerable fluctuations in flows, ranging from high flow during short-term storm events to longer periods of much lower ...

  17. Validation of the self-administered Danish Prostatic Symptom Score (DAN-PSS-1) system for use in benign prostatic hyperplasia

    DEFF Research Database (Denmark)

    Hansen, B J; Flyger, H; Brasso, K;

    1995-01-01

    To validate the Danish Prostatic Symptom Score (DAN-PSS-1), a self-administered quality-of-life questionnaire comprising 12 questions related to voiding problems and the perceived bother of each individual symptom.......To validate the Danish Prostatic Symptom Score (DAN-PSS-1), a self-administered quality-of-life questionnaire comprising 12 questions related to voiding problems and the perceived bother of each individual symptom....

  18. Prospective evaluation of complications using the modified Clavien grading system, and of success rates of percutaneous nephrolithotomy using Guy's Stone Score: A single-center experience

    Science.gov (United States)

    Mandal, Swarnendu; Goel, Apul; Kathpalia, Rohit; Sankhwar, Satyanarayan; Singh, Vishwajeet; Sinha, Rahul J.; Singh, Bhupender P.; Dalela, Divakar

    2012-01-01

    Introduction and Objectives: To prospectively document the perioperative complications of percutaneous nephrolithotomy (PCNL) using the modified Clavien grading system. Evaluation of complications and clearance rates according to stone complexity using the validated Guy's Stone Score (GSS) was also done. Materials and Methods: A total of 221 renal units underwent 278 PCNL procedures at a urology resident training center between September 2010 and September 2011 and data were recorded prospectively in our registry. Patients with co-morbidities like diabetes, renal failure, hypertension and cardiopulmonary diseases were excluded. Stone complexity was classified according to the GSS while peri-operative complications were recorded using the modified Clavien grading system. Results: Two hundred and forty-five complications were encountered in 278 PCNL procedures involving 116 renal units (41.72%). Complications of Grades 1, 2, 3a, 3b, 4a, 4b and 5 were seen in 52 (18.7%), 122 (43.8%), 42 (15.1%), 18 (6.4%), 6 (2.1%), 4 (1.4%) and 1 (0.3%) renal units respectively. There were 68, 98, 50 and 5 renal units in GSS I, II, III and IV groups, respectively. All grades of complications were more common in GSS III and IV (P<0.05). For GSS I, II, III and IV 100%, 74%, 56% and 0% of renal units, respectively, were stone-free after one session and 0%, 24%, 44% and 60% respectively needed two sessions to be stone-free. Conclusion: Although the complication rates were higher most were of low grade and self-limiting. Complications were significantly more common with higher GSS and the GSS effectively predicted stone-free rates. PMID:23450640

  19. Coalesced Multicentric Analysis of 2,351 Patients With Myelodysplastic Syndromes Indicates an Underestimation of Poor-Risk Cytogenetics of Myelodysplastic Syndromes in the International Prognostic Scoring System

    Science.gov (United States)

    Schanz, Julie; Steidl, Christian; Fonatsch, Christa; Pfeilstöcker, Michael; Nösslinger, Thomas; Tuechler, Heinz; Valent, Peter; Hildebrandt, Barbara; Giagounidis, Aristoteles; Aul, Carlo; Lübbert, Michael; Stauder, Reinhard; Krieger, Otto; Garcia-Manero, Guillermo; Kantarjian, Hagop; Germing, Ulrich; Haase, Detlef; Estey, Elihu

    2011-01-01

    Purpose The International Prognostic Scoring System (IPSS) remains the most commonly used system for risk classification in myelodysplastic syndromes (MDSs). The IPSS gives more weight to blast count than to cytogenetics. However, previous publications suggested that cytogenetics are underweighted in the IPSS. Here we investigate the prognostic impact of cytogenetic subgroups compared with that of bone marrow blast count in a large, multicentric, international patient cohort. Patients and Methods In total, 2,351 patients with MDS who have records in the German-Austrian and the MD Anderson Cancer Center databases were included and analyzed in univariate and multivariate models regarding overall survival and risk of transformation to acute myeloid leukemia (AML). The data were analyzed separately for patients treated with supportive care without specific therapy, with AML-like chemotherapy, or with other therapy regimens (low-dose chemotherapy, demethylating agents, immune modulating agents, valproic acid, and cyclosporine). Results The prognostic impact of poor-risk cytogenetic findings (as defined by the IPSS classification) on overall survival was as unfavorable as an increased (> 20%) blast count. The hazard ratio (compared with an abnormal karyotype or a bone marrow blast count < 5%) was 3.3 for poor-risk cytogenetics, 4.8 for complex abnormalities harboring chromosomes 5 and/or 7, and 3.1 for a blast count of 21% to 30% (P < .01 for all categories). The predictive power of the IPSS cytogenetic subgroups was unaffected by type of therapy given. Conclusion The independent prognostic impact of poor-risk cytogenetics on overall survival is equivalent to the impact of high blast counts. This finding should be considered in the upcoming revision of the IPSS. PMID:21519021

  20. Numerical Survey of Contaminant Transport and Self-Cleansing of Water in Nador Lagoon, Morocco

    Directory of Open Access Journals (Sweden)

    E. M. Chaabelasri

    2014-01-01

    Full Text Available Numerical simulations are presented of the flow hydrodynamics and hypothetical contaminant dispersion patterns in Nador Lagoon, a shallow lagoon with a barrier island situated on the coast of Morocco. It is found that the natural circulation forced by the tidal flow in the lagoon is greatly affected by the development of an artificial inlet in the barrier island. The case study demonstrates the potential use of modern computational hydraulics as a tool integrated in the decision support system designed to manage a lagoon ecosystem.

  1. Earthquake forecast enrichment scores

    Directory of Open Access Journals (Sweden)

    Christine Smyth

    2012-03-01

    Full Text Available The Collaboratory for the Study of Earthquake Predictability (CSEP is a global project aimed at testing earthquake forecast models in a fair environment. Various metrics are currently used to evaluate the submitted forecasts. However, the CSEP still lacks easily understandable metrics with which to rank the universal performance of the forecast models. In this research, we modify a well-known and respected metric from another statistical field, bioinformatics, to make it suitable for evaluating earthquake forecasts, such as those submitted to the CSEP initiative. The metric, originally called a gene-set enrichment score, is based on a Kolmogorov-Smirnov statistic. Our modified metric assesses if, over a certain time period, the forecast values at locations where earthquakes have occurred are significantly increased compared to the values for all locations where earthquakes did not occur. Permutation testing allows for a significance value to be placed upon the score. Unlike the metrics currently employed by the CSEP, the score places no assumption on the distribution of earthquake occurrence nor requires an arbitrary reference forecast. In this research, we apply the modified metric to simulated data and real forecast data to show it is a powerful and robust technique, capable of ranking competing earthquake forecasts.

  2. Diagnosis and prognosis of overt disseminated intravascular coagulation in a general hospital -- meaning of the ISTH score system, fibrin monomers, and lipoprotein-C-reactive protein complex formation.

    Science.gov (United States)

    Cauchie, Ph; Cauchie, Ch; Boudjeltia, K Zouaoui; Carlier, E; Deschepper, N; Govaerts, D; Migaud-Fressart, M; Woodhams, B; Brohée, D

    2006-06-01

    The meaning, the utility, and the prognostic significance of the International Society of Thrombosis and Hemostasis overt disseminated intravascular coagulation (DIC) score and other parameters of coagulation activation including soluble fibrin monomer complexes (SFMC), antithrombin and protein C consumption, and formation of lipoprotein-C-reactive protein (LP-CRP) complexes (MDA slope 1 and flag A2) were evaluated in 165 inpatients from a general hospital for whom DIC testing was required by the attending physicians. Of these 165 patients, 148 had an underlying disease that clearly justified the laboratory request from our systematic post hoc review of the clinical charts. Of these 148 patients, 28 had a positive overt DIC score, 19 had an A2 flag, and 4 had both. The DIC score was strongly related to several major markers of coagulation activation such as D-dimers, thrombin-antithrombin complexes, and soluble fibrin and was inversely related to antithrombin and protein C levels, which began to fall from DIC score 4 or higher. The formation of LP-CRP complexes was only related to Gram-negative sepsis and these patients had a strong inflammatory reaction. Independent risk factors for death were high creatininemia, positive overt DIC score, and/or presence of SFMC. In patients with positive DIC score, SFMC positivity and low levels of antithrombin and/or protein C were additional risk factors. The ISTH overt DIC score proves useful and adequate as a marker for clinically significant DIC. Illness severity is further defined by SFMC, antithrombin, and protein C levels. LP-CRP complexes are related to sepsis but not to actual overt DIC and lethal prognosis.

  3. Diagnosis and prognosis of overt disseminated intravascular coagulation in a general hospital -- meaning of the ISTH score system, fibrin monomers, and lipoprotein-C-reactive protein complex formation.

    Science.gov (United States)

    Cauchie, Ph; Cauchie, Ch; Boudjeltia, K Zouaoui; Carlier, E; Deschepper, N; Govaerts, D; Migaud-Fressart, M; Woodhams, B; Brohée, D

    2006-06-01

    The meaning, the utility, and the prognostic significance of the International Society of Thrombosis and Hemostasis overt disseminated intravascular coagulation (DIC) score and other parameters of coagulation activation including soluble fibrin monomer complexes (SFMC), antithrombin and protein C consumption, and formation of lipoprotein-C-reactive protein (LP-CRP) complexes (MDA slope 1 and flag A2) were evaluated in 165 inpatients from a general hospital for whom DIC testing was required by the attending physicians. Of these 165 patients, 148 had an underlying disease that clearly justified the laboratory request from our systematic post hoc review of the clinical charts. Of these 148 patients, 28 had a positive overt DIC score, 19 had an A2 flag, and 4 had both. The DIC score was strongly related to several major markers of coagulation activation such as D-dimers, thrombin-antithrombin complexes, and soluble fibrin and was inversely related to antithrombin and protein C levels, which began to fall from DIC score 4 or higher. The formation of LP-CRP complexes was only related to Gram-negative sepsis and these patients had a strong inflammatory reaction. Independent risk factors for death were high creatininemia, positive overt DIC score, and/or presence of SFMC. In patients with positive DIC score, SFMC positivity and low levels of antithrombin and/or protein C were additional risk factors. The ISTH overt DIC score proves useful and adequate as a marker for clinically significant DIC. Illness severity is further defined by SFMC, antithrombin, and protein C levels. LP-CRP complexes are related to sepsis but not to actual overt DIC and lethal prognosis. PMID:16680742

  4. Methane emission by termites: Impacts on the self-cleansing mechanisms of the atmosphere

    Energy Technology Data Exchange (ETDEWEB)

    Mugedo, J.Z.A. [Maseno Univ. College (Kenya)

    1996-12-31

    Termites are reported to emit large quantities of methane, carbon dioxide, carbon monoxide, hydrogen and dimethyl sulfide. The emission of other trace gases, namely C{sub 2} to C{sub 10} hydrocarbons, is also documented. We have carried out, both in the field and in the laboratory, measurements of methane emissions by Macrotermes subhyalinus (Macrotermitinae), Trinervitermes bettonianus (Termitinae), and unidentified Cubitermes and Microcerotermes species. Measured CH{sub 4} field flux rates ranged from 3.66 to 98.25g per m{sup 2} of termite mound per year. Laboratory measurements gave emission rates that ranged from 14.61 to 165.05 mg CH{sub 4} per termite per year. Gaseous production in all species sampled varied both within species and from species to species. Recalculated global emission of methane from termites was found to be 14.0 x 10{sup 12} g CH{sub 4}, per year. From our study, termites contribution to atmospheric methane content is between 1.11% and 4.25% per year. This study discusses the greenhouse effects as well as photochemical disposal of methane in the lower atmosphere in the tropics and the impacts on the chemistry of HO{sub x} systems and CL{sub x} cycles.

  5. The Value of Botox-A in Acute Radiation Proctitis: Results From a Phase I/II Study Using a Three-Dimensional Scoring System

    International Nuclear Information System (INIS)

    Purpose: Acute radiation proctitis (ARP) is a common side effect of pelvic radiotherapy, and its management is challenging in daily practice. The present phase I/II study evaluates the safety and efficacy of the botulinum toxin A (BTX-A) in ARP treatment for rectal cancer patients undergoing neoadjuvant high-dose-rate endorectal brachytherapy (HDREBT). Methods and Materials: Fifteen patients, treated with neoadjuvant HDREBT, 26-Gy in 4 fractions, received the study treatment that consisted of a single injection of BTX-A into the rectal wall. The injection was performed post-HDREBT and prior to the development of ARP. The control group, 20 such patients, did not receive the BTX-A injection. Both groups had access to standard treatment with hydrocortisone rectal aerosol foam (Cortifoam) and anti-inflammatory and narcotic medication. The ARP was clinically evaluated by self-administered daily questionnaires using visual analog scores to document frequency and urgency of bowel movements, rectal burning/tenesmus, and pain symptoms before and after HDREBT. Results: At the time of this analysis, there was no observed systemic toxicity. Patient compliance with the self-administered questionnaire was 100% from week 1 to 4, 70% during week 5, and 40% during week 6. The maximum tolerated dose was established at the 100-U dose level, and noticeable mean differences were observed in bowel frequency (p = 0.016), urgency (p = 0.007), and pain (p = 0.078). Conclusions: This study confirms the feasibility and efficacy of BTX-A intervention at 100-U dose level for study patients compared to control patients. A phase III study with this dose level is planned to validate these results.

  6. Are free energy calculations useful in practice? A comparison with rapid scoring functions for the p38 MAP kinase protein system.

    Science.gov (United States)

    Pearlman, D A; Charifson, P S

    2001-10-11

    Precise thermodynamic integration free energy simulations have been applied to a congeneric series of 16 inhibitors to the p38 MAP kinase protein for which the experimental binding data (IC(50)) is known. The relative free energy of binding for each compound has been determined. For comparison, the same series of compounds have also scored using the best rapid scoring functions used in database screening. From the results of these calculations, we find (1) that precise free energy simulations allow predictions that are reliable and in good agreement with experiment; (2) that predictions of lower reliability, but still in good qualitative agreement with experiment, can be obtained using the OWFEG free energy grid method, at a much lower computational cost; (3) and that other methods, not based on free energy simulations yield results in much poorer agreement with experiment. A new predictive index, which measures the reliability of a prediction method in the context of normal use, is defined and calculated for each scoring method. Predictive indices of 0.84, 0.56, 0.04, -0.05, and 0.25 are calculated for thermodynamic integration, OWFEG, ChemScore, PLPScore, and Dock Energy Score, respectively, where +1.0 is perfect correct prediction, -1.0 is perfect incorrect prediction, and 0.0 is random.

  7. International Society of Thrombosis and Hemostasis Scoring System for disseminated intravascular coagulation ≥ 6: a new predictor of hemorrhagic early death in acute promyelocytic leukemia.

    Science.gov (United States)

    Mitrovic, Mirjana; Suvajdzic, Nada; Bogdanovic, Andrija; Kurtovic, Nada Kraguljac; Sretenovic, Aleksandra; Elezovic, Ivo; Tomin, Dragica

    2013-03-01

    High-hemorrhagic early death (ED) rate is a major impediment in the managing of acute promyelocytic leukemia (APL). In our group of 56 newly diagnosed APL patients, ED occurred in 12 subjects, due to endocranial bleeding (8/12), differentiation syndrome (2/12), or infection (2/12). Predictors of hemorrhagic ED were as follows: white blood cells count ≥ 20 × 10(9)/L (P = 0.002337), Eastern cooperative oncology group performance status ≥ 3 (P = 0.00173), fibrinogen level disseminated intravascular coagulation (ISTH DIC score) ≥ 6 (P = 0.00741). Multivariate analysis indicated ISTH DIC score ≥ 6 to be the most significant predictor for hemorrhagic ED (P = 0.008). The main finding of this study is that simple coagulation-related tests, performed on hospital admission and combined in the ISTH DIC score, might help to identify patients at high risk for fatal bleeding needing more aggressive supportive measures.

  8. Validation of the revised international prognostic scoring system (IPSS-R) in patients with lower-risk myelodysplastic syndromes: a report from the prospective European LeukaemiaNet MDS (EUMDS) registry

    NARCIS (Netherlands)

    Swart, L. de; Smith, A.; Johnston, T.W.; Haase, D.; Droste, J.; Fenaux, P.; Symeonidis, A.; Sanz, G.; Hellstrom-Lindberg, E.; Cermak, J.; Germing, U.; Stauder, R.; Georgescu, O.; MacKenzie, M.; Malcovati, L.; Holm, M.S.; Almeida, A.M.; Madry, K.; Slama, B.; Guerci-Bresler, A.; Sanhes, L.; Beyne-Rauzy, O.; Luno, E.; Bowen, D.; Witte, T.J. de

    2015-01-01

    Baseline characteristics, disease-management and outcome of 1000 lower-risk myelodysplastic syndrome (MDS) patients within the European LeukaemiaNet MDS (EUMDS) Registry are described in conjunction with the validation of the revised International Prognostic Scoring System (IPSS-R). The EUMDS regist

  9. Predicting mortality after congenital heart surgeries: Evaluation of the Aristotle and Risk Adjustement in Congenital Heart surgery-1 risk prediction scoring systems: A retrospective single center analysis of 1150 patients

    Directory of Open Access Journals (Sweden)

    Shreedhar S Joshi

    2014-01-01

    Full Text Available Aims and Objectives: To validate Aristotle basic complexity and Aristotle comprehensive complexity (ABC and ACC and risk adjustment in congenital heart surgery-1 (RACHS-1 prediction models for in hospital mortality after surgery for congenital heart disease in a single surgical unit. Materials and Methods: Patients younger than 18 years, who had undergone surgery for congenital heart diseases from July 2007 to July 2013 were enrolled. Scoring for ABC and ACC scoring and assigning to RACHS-1 categories were done retrospectively from retrieved case files. Discriminative power of scoring systems was assessed with area under curve (AUC of receiver operating curves (ROC. Calibration (test for goodness of fit of the model was measured with Hosmer-Lemeshow modification of χ2 test. Net reclassification improvement (NRI and integrated discrimination improvement (IDI were applied to assess reclassification. Results: A total of 1150 cases were assessed with an all-cause in-hospital mortality rate of 7.91%. When modeled for multivariate regression analysis, the ABC (χ2 = 8.24, P = 0.08, ACC (χ2 = 4.17 , P = 0.57 and RACHS-1 (χ2 = 2.13 , P = 0.14 scores showed good overall performance. The AUC was 0.677 with 95% confidence interval (CI of 0.61-0.73 for ABC score, 0.704 (95% CI: 0.64-0.76 for ACC score and for RACHS-1 it was 0.607 (95%CI: 0.55-0.66. ACC had an improved predictability in comparison to RACHS-1 and ABC on analysis with NRI and IDI. Conclusions: ACC predicted mortality better than ABC and RCAHS-1 models. A national database will help in developing predictive models unique to our populations, till then, ACC scoring model can be used to analyze individual performances and compare with other institutes.

  10. Estimation of genotype X environment interactions, in a grassbased system, for milk yield, body condition score,and body weight using random regression models

    NARCIS (Netherlands)

    Berry, D.P.; Buckley, F.; Dillon, P.; Evans, R.D.; Rath, M.; Veerkamp, R.F.

    2003-01-01

    (Co)variance components for milk yield, body condition score (BCS), body weight (BW), BCS change and BW change over different herd-year mean milk yields (HMY) and nutritional environments (concentrate feeding level, grazing severity and silage quality) were estimated using a random regression model.

  11. Reliability of a Retail Food Store Survey and Development of an Accompanying Retail Scoring System to Communicate Survey Findings and Identify Vendors for Healthful Food and Marketing Initiatives

    Science.gov (United States)

    Ghirardelli, Alyssa; Quinn, Valerie; Sugerman, Sharon

    2011-01-01

    Objective: To develop a retail grocery instrument with weighted scoring to be used as an indicator of the food environment. Participants/Setting: Twenty six retail food stores in low-income areas in California. Intervention: Observational. Main Outcome Measure(s): Inter-rater reliability for grocery store survey instrument. Description of store…

  12. Evidences of validity of bender – gradual scoring system (B-SPG / Evidências de validade do bender – sistema de pontuação gradual (B-SPG

    Directory of Open Access Journals (Sweden)

    Ana Paula Porto Noronha

    2005-01-01

    Full Text Available This study aimed to gather evidences of validity for the Bender test – Gradual Scoring System (B-SPG, investigating developmental changes based on the relationships between its scores and the ages of the children. The study investigated 1052 children attending from pre-school to fourth grade of eight municipal and state public schools of Campinas (a city in the state of São Paulo, Brazil and the surrounding region. Ages ranged from six to ten years old, with an average of 8,35. The findings indicated that according to the increase of age, the B-SPG scores diminished, suggesting that the distortions progressively diminish as the children become older. Although other studies are suggested, the results presented here are consonant with researches that sought to establish that it is possible too find a maturational character among the figures of the test.

  13. Utility of sepsis biomarkers and the infection probability score to discriminate sepsis and systemic inflammatory response syndrome in standard care patients.

    Directory of Open Access Journals (Sweden)

    Franz Ratzinger

    Full Text Available Physicians are regularly faced with severely ill patients at risk of developing infections. In literature, standard care wards are often neglected, although their patients frequently suffer from a systemic inflammatory response syndrome (SIRS of unknown origin. Fast identification of patients with infections is vital, as they immediately require appropriate therapy. Further, tools with a high negative predictive value (NPV to exclude infection or bacteremia are important to increase the cost effectiveness of microbiological examinations and to avoid inappropriate antibiotic treatment. In this prospective cohort study, 2,384 patients with suspected infections were screened for suffering from two or more SIRS criteria on standard care wards. The infection probability score (IPS and sepsis biomarkers with discriminatory power were assessed regarding their capacity to identify infection or bacteremia. In this cohort finally consisting of 298 SIRS-patients, the infection prevalence was 72%. Bacteremia was found in 25% of cases. For the prediction of infection, the IPS yielded 0.51 ROC-AUC (30.1% sensitivity, 64.6% specificity. Among sepsis biomarkers, lipopolysaccharide binding protein (LBP was the best parameter with 0.63 ROC-AUC (57.5% sensitivity, 67.1% specificity. For the prediction of bacteremia, the IPS performed slightly better with a ROC-AUC of 0.58 (21.3% sensitivity, 65% specificity. Procalcitonin was the best discriminator with 0.78 ROC-AUC, 86.3% sensitivity, 59.6% specificity and 92.9% NPV. Furthermore, bilirubin and LBP (ROC-AUC: 0.65, 0.62 might also be considered as useful parameters. In summary, the IPS and widely used infection parameters, including CRP or WBC, yielded a poor diagnostic performance for the detection of infection or bacteremia. Additional sepsis biomarkers do not aid in discriminating inflammation from infection. For the prediction of bacteremia procalcitonin, and bilirubin were the most promising parameters, which

  14. Fingerprinting of music scores

    Science.gov (United States)

    Irons, Jonathan; Schmucker, Martin

    2004-06-01

    Publishers of sheet music are generally reluctant in distributing their content via the Internet. Although online sheet music distribution's advantages are numerous the potential risk of Intellectual Property Rights (IPR) infringement, e.g. illegal online distributions, disables any innovation propensity. While active protection techniques only deter external risk factors, additional technology is necessary to adequately treat further risk factors. For several media types including music scores watermarking technology has been developed, which ebeds information in data by suitable data modifications. Furthermore, fingerprinting or perceptual hasing methods have been developed and are being applied especially for audio. These methods allow the identification of content without prior modifications. In this article we motivate the development of watermarking and fingerprinting technologies for sheet music. Outgoing from potential limitations of watermarking methods we explain why fingerprinting methods are important for sheet music and address potential applications. Finally we introduce a condept for fingerprinting of sheet music.

  15. Relationship of Apgar Scores and Bayley Mental and Motor Scores

    Science.gov (United States)

    Serunian, Sally A.; Broman, Sarah H.

    1975-01-01

    Examined the relationship of newborns' 1-minute Apgar scores to their 8-month Bayley mental and motor scores and to 8-month classifications of their development as normal, suspect, or abnormal. Also investigated relationships between Apgar scores and race, longevity, and birth weight. (JMB)

  16. ALVARADO SCORE AND ITS CORRELATION WITH APPENDICITIS

    Directory of Open Access Journals (Sweden)

    Surajit

    2015-11-01

    Full Text Available BACKGROUND Acute appendicitis is the most common cause of an acute abdomen. The treatment is surgical and negative appendectomy rates are high. The Alvarado score can be used to stratify patients with symptoms of suspected appendicitis. It enables risk stratification in patients presenting with abdominal pain, linking the probability of appendicitis to recommendations regarding discharge, observation or surgical intervention. AIMS AND OBJECTIVES This study was conducted to evaluate Alvarado scoring system for diagnosis of acute appendicitis and its correlation with operative finding and histopathology. Patients presenting in the Emergency Department in primary and secondary care settings, especially in low-resource countries where emergency CT scan is not available round the clock can be benefitted from the Alvarado scoring system. MATERIALS AND METHODS The score has 6 clinical items and 2 laboratory measurements with a total 10 points. This study was conducted on 98 patients irrespective of age and sex, who attended the emergency and OPD during the course of the work with symptoms suggestive of acute appendicitis including abdominal pain, rebound tenderness, nausea, vomiting or elevated temperature with/without leukocytosis and neutrophilia, and charts were made for each of the patients. Using the scoring system for appendicitis developed by Alvarado, each chart was scored. Out of 98 patients, 7 patients with Alvarado score of ≤ 4 were treated conservatively and later discharged in stable condition. The remaining 91 patients with score of 5-6 and those with score of ≥ 7 were operated. Operative finding and later histopathological examination confirmed the diagnosis of acute appendicitis in 83 patients out of 91 who underwent appendectomy. RESULT In this study, we compared the Alvarado score of the patient recorded prior to operation with the operative finding and histopathological report. The results were statistically analysed by Student

  17. The value of APACHE Ⅱ scoring system in assessment of seyerity and prognosis of patients with organophosphate insecticide poisoning%APACHE Ⅱ评分对有机磷中毒患者病情评估的意义

    Institute of Scientific and Technical Information of China (English)

    胡念丹; 黄敏; 李文强

    2011-01-01

    Objective:To evaluate the severity and the prognosis of the organophosphate insecticide poisoning by using APACHE Ⅱ scoring system. Method: Fifty-one patients with organophosphate insecticide poisoning admitted in our hospital were studied retrospectively. Data associated with APACHE Ⅱ scoring system were recorded and analyzed statistically.Result:The APACHE Ⅱ score of the 51 patients enrolled in our study were ranged from 3 to 28. The APACHE Ⅱ score was (21.43 ± 5.41)in the 7 deaths and (8. 75 ± 3.29 )in the 44 survivors. There was significant differences between the two groups(P<0.01). Conclusion:APACHE Ⅱ scoring system may have some value in predict the prognosis of organophosphate insecticide poisoning.%目的:探讨应用急性生理和慢性健康状况(APACHE Ⅱ)评分评估有机磷农药中毒患者的病情严重程度及预后的意义.方法:回顾性分析我院有机磷农药中毒患者51例,记录与APACHE Ⅱ评分系统相关的数据,并对患者的APACHE Ⅱ评分进行统计学分析.结果:51例患者APACHE Ⅱ评分3~28分.7例死亡患者APACHE Ⅱ评分(21.43±5.41)分,44例存活患者APACHE Ⅱ评分(8.75±3.29)分,两组之间差异有统计学意义(P<0.01).结论:APACHE Ⅱ评分对中毒的预后预测可能有一定的作用.

  18. MRI定量分析评价类风湿性关节炎疗效的初步临床应用%Clinical value of assessing the therapy effect of rheumatoid arthritis using MRI scoring system

    Institute of Scientific and Technical Information of China (English)

    夏鹏; 王德杭; 蒋兆贯; 陶娟; 顾光官; 冯阳; 吴斌龙

    2011-01-01

    目的 探讨MRI评分评价类风湿性关节炎( rheumatoid arthritis,RA)疗效的临床价值.方法 对临床确诊的59例RA患者双腕关节及双手分别于治疗前及疗程结束后进行MRI成像,分析治疗前后MRI图像,根据OMERACT RAMRIS评分系统分别进行评分并记录.根据临床资料对病人的疗效进行判断.分析MRI评分、MR征象与临床相关活动性指标及临床疗效的相关性.结果 骨髓水肿评分与ESR间有相关性(r=0.278,P=0.033);MRI征象总评分与ESR (r=0.272,P=0.037)和CRP(r=0.279,P=0.033)有相关性.在治疗有效和无效的病人中,治疗后MRI总评分变化值有差异(15.8±9.8 vs 5.3±13.3,Mann-Whitney Test,P<0.001).ROC曲线分析结果 显示,以治疗后总评分差值≥10.5分为诊断治疗有效的标准,敏感度为81%,特异度为71.1%.结论 MRI评分可反映RA的活动性和评价临床疗效,具有一定的临床应用价值.%Obiective to investigate the clinical values of assessing the therapy effect of theumatoid arthritis using MRI scoring system.Materials and methods MR images of both wrists and the 2nd to Sth metacarPophalangeal joints of 59 patients with RA were analyzed.MRI scores of each patient were acquired using OMERACT RAMRIS Scoring System.The relationships between MRI score of each sign , between MRI score and clinical data were analyzed respectively.Results There were significant correlation between bone edema score and ESR( F0.278 ,p=0.033).MRI total score and ESR( r=0.272.P=0.03 7).MRI total score and CRP(r=0.279.P=0.033).There was a significant difference of MRI total score changes after therapY between response and non-response group (15.8±9.8 vs 5.3±13.3,Mann-Whitney Test (P<0.001).The results of ROC analysis for identification of responding lesions showed that threshold MRI total score changes after therapy of 10.5 had 81% sensitivitv and 71.1% specificity.Conclusion the MRI scoring system can be used to assess the activity of RA and evaluate the

  19. Tradução e adaptação cultural do Asthma Control Scoring System (Sistema de Escore para Controle Abrangente da Asma para uso no Brasil The Asthma Control Scoring System: translation and cross-cultural adaptation for use in Brazil

    Directory of Open Access Journals (Sweden)

    Michelle Gonçalves de Souza Tavares

    2010-12-01

    Full Text Available OBJETIVO: Traduzir e adaptar culturalmente, para uso no Brasil, um instrumento específico de escore para o controle abrangente da asma, denominado Asthma Control Scoring System (ACSS. MÉTODOS: O protocolo incluiu dez etapas: autorização escrita do autor do ACSS; tradução do instrumento para a língua portuguesa do Brasil por três tradutores; análise e comparação das três versões por um comitê revisor; retradução literal para o inglês; revisão e harmonização da retradução; aprovação do autor do ACSS; revisão da tradução por especialistas; desdobramento cognitivo: teste da clareza, compreensão e aceitabilidade junto à população alvo (avaliação da tradução por 10 profissionais da área da saúde; segundo desdobramento cognitivo: revisão da nova versão por um segundo grupo de profissionais da área de saúde; e reconciliação e elaboração da versão final pelo comitê revisor. RESULTADOS: A versão do ACSS em português do Brasil apresentou clareza, compreensão e aceitabilidade. O instrumento foi considerado abrangente por englobar as manifestações clínicas, funcionais e inflamatórias da asma. CONCLUSÕES: Com o uso desta metodologia criteriosa empregada para a adaptação transcultural do ACSS, asseguramos sua adequação cultural para uso no Brasil. O uso desse instrumento poderá facilitar futuros estudos sobre o controle da asma.OBJECTIVE: The translation and cross-cultural adaptation of a specific scoring instrument for the comprehensive control of asthma, the Asthma Control Scoring System (ACSS, for use in Brazil. METHODS: The protocol included ten steps: acquisition of written permission from the author of the ACSS; translation of the instrument to Brazilian Portuguese, carried out by three separate translators; analysis and comparison of the three versions by a review committee; literal back-translation to English; review and harmonization of the back-translation; acquisition of the approval of the

  20. Prediction of outcome of elderly patients with respiratory failure: comparison of current scoring systems%不同预后评分在老年呼吸衰竭患者中的应用

    Institute of Scientific and Technical Information of China (English)

    郭超; 解立新; 冯丹

    2011-01-01

    Objective To evaluate the predictive power of current scoring systems applied in elderly patients with respiratory failure. Methods Data of 159 elderly patients with respiratory failure, also meeting the criteria of multiple organ dysfunction syndrome in the elderly (MODSE), being admitted to PLA General Hospital from January 2009 to March 2010 were analyzed with four scoring systems, i.e. acute physiology and chronic health evaluation (APACHE Ⅱ , APACHE Ⅲ ), simplified acute physiology score Ⅱ (SAPS Ⅱ ),as well as multiple organ dysfunction score (Marshall score), for the prediction of their outcome on the first day after admission, and the predictive power of respective system was compared. Results One hundred and fifty-nine patients were involved, with a mean age of (75.26±7. 87) years, and a 28-day mortality of 53. 5%. Incidence of organ failure and prognosis scores in nonsurvivors were significantly higher than those in survivors (APACHE Ⅱ score: 27. 88 ± 8. 19 vs. 17.73 ± 6.21; APACHE Ⅲ score: 101.10 ± 29. 81 vs.64. 24±21.98; SAPS Ⅱ score: 59. 70±17.68 vs. 38. 05±12. 10; Marshall score: 8. 59±3. 15 vs. 4. 90±2. 66; organ failure: 4. 60±1.14 vs. 2. 88±0. 88, all P<0. 01). Among the four scoring systems, SAPS Ⅱpresented excellence in sensitivity (91.76 % ), while APACHE Ⅲ in specificity (91.89 % ). Area under curve of receiver operator characteristic of all scoring systems reached 0. 820 (0. 829 for APACHE Ⅱ , 0. 836 for APACHE Ⅲ , 0. 844 for SAPS Ⅱ , 0. 820 for Marshall score). Conclusion All the four current scoring systems, i.e. APACHE Ⅱ , APACHE Ⅲ , SAPS Ⅱ and Marshall score, presented satisfactory predictive power in prognosis of elderly patients with respiratory failure.%目的 比较不同评分系统对老年呼吸衰竭患者预后的评价能力.方法 收集解放军总医院2009年1月至2010年3月收住的老年呼吸衰竭患者159例,均存在2个或以上器官功能不全,符合老年多器官功能

  1. Progress of evidence-based wound cleansing technology%伤口清洗循证护理相关技术进展

    Institute of Scientific and Technical Information of China (English)

    马静; 母晓凤; 刁勇

    2014-01-01

    伤口清洗是急性和慢性伤口护理不可分割的一部分,优良的护理质量是伤口愈合的关键。而伤口护理的终极目标是将机会性感染的风险降到最低,同时促进健康肉芽组织的发展,并启动和促进愈合过程。随着Svoboda等应用自来水替代灭菌生理盐水进行伤口清洗的大量实验的进行,揭开了伤口循证护理研究的序幕。本研究就近年来有关伤口清洗循证护理研究的结果进行综述,综合比较各种清洗方法及清洗剂对伤口愈合的影响,希望促进伤口清洗护理从例行仪式走向循证科学。%Wound cleansing is an integral part of acute and chronic wound care,good-quality care is the key to wound healing. The ultimate goal of wound care is to minimize the risk of opportunistic infection and accelerate the proliferation of healthy granulation tissue at the same time as well as activate and promote the healing process.But the study of wound cleansing did not begin until 20 years ago.With experiments using tap water instead of sterilized saline to wash wounds done by Svoboda,a prelude to evidence-based nursing has been opened.This paper summarizes the experimental results on wound cleaning that uses evidence-based nursing methods.We further compare the effects of different cleaning methods and cleaning agents on wound healing,hoping to push forward wound cleansing from a ritual to evidence-based nursing science.

  2. The first Latin-American risk stratification system for cardiac surgery: can be used as a graphic pocket-card score.

    Science.gov (United States)

    Carosella, Victorio C; Navia, Jose L; Al-Ruzzeh, Sharif; Grancelli, Hugo; Rodriguez, Walter; Cardenas, Cesar; Bilbao, Jorge; Nojek, Carlos

    2009-08-01

    This study aims to develop the first Latin-American risk model that can be used as a simple, pocket-card graphic score at bedside. The risk model was developed on 2903 patients who underwent cardiac surgery at the Spanish Hospital of Buenos Aires, Argentina, between June 1994 and December 1999. Internal validation was performed on 708 patients between January 2000 and June 2001 at the same center. External validation was performed on 1087 patients between February 2000 and January 2007 at three other centers in Argentina. In the development dataset the area under receiver operating characteristics (ROC) curve was 0.73 and the Hosmer-Lemeshow (HL) test was P=0.88. In the internal validation ROC curve was 0.77. In the external validation ROC curve was 0.81, but imperfect calibration was detected because the observed in-hospital mortality (3.96%) was significantly lower than the development dataset (8.20%) (Pcard score allows an easy bedside application with acceptable statistic precision.

  3. Prognostic utility of plasma S100A12 levels to establish a novel scoring system for predicting mortality in maintenance hemodialysis patients: a two-year prospective observational study in Japan

    Directory of Open Access Journals (Sweden)

    Shiotsu Yayoi

    2013-01-01

    Full Text Available Abstract Background S100A12 protein is an endogenous receptor ligand for advanced glycation end products. In this study, the plasma S100A12 level was assessed as an independent predictor of mortality, and its utility in clinical settings was examined. Methods In a previous cross-sectional study, plasma S100A12 levels were measured in 550 maintenance hemodialysis patients to determine the association between S100A12 and the prevalence of cardiovascular diseases (CVD. In this prospective study, the risk of mortality within a two-year period was determined. An integer scoring system was developed to predict mortality on the basis of the plasma S100A12 levels. Results Higher plasma S100A12 levels (≥18.79 ng/mL were more closely associated with higher all-cause mortality than lower plasma S100A12 levels (P = 0.001. Multivariate Cox proportional hazards analysis revealed higher plasma S100A12 levels [hazard ratio (HR, 2.267; 95% confidence interval (CI, 1.195–4.302; P = 0.012], age ≥65 years (HR, 1.961; 95%CI, 1.017–3.781; P = 0.044, serum albumin levels P = 0.012, and history of CVD (HR, 2.068; 95%CI, 1.146–3.732; P = 0.016 to be independent predictors of two-year all-cause mortality. The integer score was derived by assigning points to these factors and determining total scores. The scoring system revealed trends across increasing scores for predicting the all-cause mortality [c-statistic = 0.730 (0.656–0.804]. The resulting model demonstrated good discriminative power for distinguishing the validation population of 303 hemodialysis patients [c-statistic = 0.721 (0.627–0.815]. Conclusion The results indicate that plasma S100A12 level is an independent predictor for two-year all-cause mortality. A simple integer scoring system was therefore established for predicting mortality on the basis of plasma S100A12 levels.

  4. Clinical study on validation systemic inflammatory response syndrome score in predicting prognosis in acute craniocerebral trauma%SIRS评分应用于预测急性颅脑损伤患者预后的临床研究

    Institute of Scientific and Technical Information of China (English)

    朱志军; 黄文; 欧阳毅

    2008-01-01

    目的 探讨全身炎症反应综合征(SIRS)评分预测急性颅脑损伤患者预后的作用和意义.方法 对收治的620例急性颅脑损伤患者在入院24 h内进行SIRS评分及GCS评分,分析不同SIRS分值患者的病死率、相同年龄患者不同GCS分值与SIRS分值及预后的关系.结果 随着SIRS分值的升高,患者病死率增加,当SIRS分值≥2分时患者病死率显著升高,与SIRS分值<2分时比较差异有统计学意义(P<0.05);相同年龄组当SIRS分值≥2分时,GCS分值为8~12分的患者病死率15.38%(4/26),GCS分值<8分的患者病死率50.00%(8/16),二者差异有统计学意义(P<0.05).结论 SIRS评分具有独立预测颅脑损伤患者预后的作用,有一定的临床应用价值.%Objective To explore the effect and significance of systemic inflammatory response syndrome(SIRS )score in predicting prognosis in acute craniocerebral trauma. Methods The clinical data of 620 patients were collected at admission from January 2003 to December 2007, GCS and SIRS score were calculated in 24 hours.The relation of the mortality rates and GCS score were analyzed in different SIRS score patients by controlling age. Results With SIRS score increasing,mortality rates increased as well,and pa-tients with SIRS (score≥2) mortality rates had significantly higher,and also in the same age and GCS score group.Mortality rotes were significant in staifistics (P<0.05). Conclusion SIRS score is significant inde-pendent predicting prognosis in acute craniocerebral trauma and in clinic.

  5. 简化急性生理学评分Ⅲ与其他评分方法对急诊严重脓毒症患者28 d死亡的预测能力比较%Comparison of simplified acute physiology score Ⅲ and other scoring systems in prediction of 28-day ;prognosis in patients with severe sepsis

    Institute of Scientific and Technical Information of China (English)

    李岩; 李春盛

    2015-01-01

    SAPSⅡ评分预测能力相当,可用于对急诊ICU严重脓毒症患者的预后进行预测,但SAPSⅢ评分有不适合预测急诊ICU脓毒症患者预后的选项,导致SAPSⅢ评分在预测急诊ICU脓毒症患者的预后方面并未优于其他评分。%Objective To investigate the power of the simplified acute physiology score Ⅲ ( SAPSⅢ) for prediction of outcome for patients with severe sepsis admitted to the intensive care unit ( ICU ). Methods A retrospective study was conducted. 677 severe sepsis patients with age ≥ 18 years old and the survival time in emergency ICU≥24 hours admitted to the emergency ICU of Beijing Chaoyang Hospital Affiliated to Capital Medical University from January 2008 to December 2011 were enrolled. The acute physiology and chronic health evaluationⅡ ( APACHEⅡ), sequential organ failure assessment ( SOFA ), SAPSⅡ, SAPSⅢ, and mortality in emergency department sepsis ( MEDS ) scores were recorded based on the poorest value within 24 hours of ICU admission. The 28-day result as denoted as survival or death was considered as the end point of the study. The ability to predict mortality by the score systems was assessed by using receiver operating characteristic ( ROC ) curve analysis and binary logistic regression models. Results Among the 677 patients with severe sepsis, 284 cases died within 28 days after admission, and the mortality rate was 41.9%. Compared with survivors, the patients in non-survival group was older with higher APACHEⅡ, SOFA, SAPSⅡ, SAPSⅢ, and MEDS scores and higher ratio of underlying diseases, such as primary hypertension and renal dysfunction, and they had more organ injury, higher ratio of lung infection and bacterial infection ( P 0.05 ). The MEDS score in predicting the prognosis was obviously better than that of APACHEⅡ, SOFA, SAPSⅡ, and SAPSⅢscores ( all P<0.05 ). The MEDS score showed the best sensitivity ( 91.5%), and specificity ( 89.1%). The 28-day mortality in cases

  6. Inspection Score and Grading System for Food Services in Brazil: The Results of a Food Safety Strategy to Reduce the Risk of Foodborne Diseases during the 2014 FIFA World Cup

    Science.gov (United States)

    da Cunha, Diogo T.; Saccol, Ana L. de Freitas; Tondo, Eduardo C.; de Oliveira, Ana B. A.; Ginani, Veronica C.; Araújo, Carolina V.; Lima, Thalita A. S.; de Castro, Angela K. F.; Stedefeldt, Elke

    2016-01-01

    In 2014, Brazil hosted one of the most popular sport competitions in the world, the FIFA World Cup. Concerned about the intense migration of tourists, the Brazilian government decided to deploy a food safety strategy based on inspection scores and a grading system applied to food services. The present study aimed to evaluate the results of the food safety strategy deployed during the 2014 FIFA World Cup in Brazil. To assess food safety, an evaluation instrument was applied twice in 1927 food service establishments from 26 cities before the start of the competition. This instrument generated a food safety score for each establishment that ranged from 0.0 (no flaws observed) to 2565.95, with four possible grades: A (0.0–13.2); B (13.3–502.6); C (502.7–1152.2); and pending (more than 1152.3). Each food service received a stamp with the grade of the second evaluation. After the end of the World Cup, a study was conducted with different groups of the public to evaluate the acceptance of the strategy. To this end, 221 consumers, 998 food service owners or managers, 150 health surveillance auditors, and 27 health surveillance coordinators were enrolled. These participants completed a survey with positive and negative responses about the inspection score system through a 5-point Likert scale. A reduction in violation scores from 393.1 to 224.4 (p responses on “system reliability” presented a mean of 4.0 or more, indicating that the public believed this strategy is reliable for communicating risks and promoting food safety. The strategy showed positive results regarding food safety and public acceptance. The deployed strategy promoted improvements in the food safety of food services. The implementation of a permanent policy may be well accepted by the public and may greatly contribute to a reduction in foodborne diseases (FBDs). PMID:27199943

  7. Application of composite scoring system in evaluating the early stroke risk after transient ischemic attack risk%联合评分评估 TIA 后早期卒中风险的应用研究

    Institute of Scientific and Technical Information of China (English)

    高双苓; 王建桥; 王学仕; 李战永

    2014-01-01

    Objective To investigate the application of composite scoring system in evaluating the early stroke risk after transient ischemic attack risk(TIA). Methods 120 patients with TIA were evaluated by the ABCD2 score ,and then the hyper-sensitive C-reactive protein (hs-CRP) and fibrinogen (FIB) in serum were measured. The ABCD2 score combined with the re-sults of hs-CRP and FIB formed the composite scoring system ,and then the area under the receiver operating characteristic (ROC) curve were compared between the ABCD2 score and the composite scoring system. Results The area under the ROC curve of composite scoring system was significantly larger than that of ABCD 2.Conclusion The composite scoring system cri-teria can effectively predict the early occurrence of cerebral infarction after TIA ,and guide the aggressive diagnostic protocols and therapy of T IA.%目的:探讨联合评分方法对短暂性脑缺血发作(transient is chemic attack ,TIA)后早期卒中风险进行评估的效能。方法收集120例TIA患者,通过头DWI明确有无新鲜梗死。入院后对患者进行ABCD2评分,检测患者血清超敏C反应蛋白(hypersensitive C-reactive protein ,hs-CRP)、血浆纤维蛋白原(fibrinogen ,FIB)的含量。在ABCD2评分基础上,结合血清hs-CRP、FIB结果形成联合评分,对比分析 TIA后1周内ABCD2评分与联合评分两种方法的评估效能。结果120例T IA患者中,39例(32.5%)在发病1周内发生脑梗死。ABCD2评分与联合评分两种方法结果一致,脑梗死发病率由高到低顺序为:高危>中危>低危。联合评分低、中危组人数减少,高危组人数增加。与ABCD2评分比较,联合评分低、中危组脑梗死发病率降低,高危组脑梗死发病率升高。联合评分的ROC曲线下面积显著大于ABCD2评分(P<0.001)。结论结合临床生化检验结果的联合评分效能高于单纯的ABCD2评分,联合评

  8. Confidence scores for prediction models

    DEFF Research Database (Denmark)

    Gerds, Thomas Alexander; van de Wiel, MA

    2011-01-01

    modelling strategy is applied to different training sets. For each modelling strategy we estimate a confidence score based on the same repeated bootstraps. A new decomposition of the expected Brier score is obtained, as well as the estimates of population average confidence scores. The latter can be used...... to distinguish rival prediction models with similar prediction performances. Furthermore, on the subject level a confidence score may provide useful supplementary information for new patients who want to base a medical decision on predicted risk. The ideas are illustrated and discussed using data from cancer...

  9. Therapeutic intervention scoring system application in a pediatric intensive care unit Aplicação do índice de intervenção terapêutica em unidade de terapia intensiva pediátrica

    Directory of Open Access Journals (Sweden)

    Pedro Celiny Ramos Garcia

    2009-08-01

    Full Text Available Introduction: Indices of gravity aim to estimate the disease’s severity. The Therapeutic Intervention Scoring System – 28 (TISS-28 is used in Intensive Care Units as an indirect index to estimate the disease`s gravity interval, which has also been recently used to relate the nursing workload Objective: To review each operational item/definition of the Therapeutic Intervention Scoring System (TISS-28, making a re-reading in order to systematize the data collection practice in Pediatric Intensive Care Units (PICUs. Materials and Methods: An integrative revision research of medical and nursing literature through the base of data from Medical Literature Analysis and Retrieval System Online (MEDLINE and Scientific Electronic Library Online (SciELO using the terms Intensive Care Units, scales and Therapeutic Intervention Scoring System-28 or TISS-28. The articles were selected according to their relevance, as the authors opinion. Results: Preliminary studies show that the use of TISS-28 in ICU of adults patients, has helped in the evolutionary clinical assessment of the patient’s worsening, besides associations between death and elevated scores. The items/operational definitions evaluated in this score are reviewed in order to facilitate the interpretation of each item in the TISS -28 daily application in Pediatric Intensive Care Unit (PICU. Conclusion: The daily assessment of the 28 TISS variables allows the acquirement of an evolutionary profile of hospitalized children, which can help to increase the knowledge of the hospitalized child clinical picture and its prognosis.Introdução: Índices de gravidade buscam estimar a severidade da doença, sendo o Therapeutic Intenvention Scoring System-28 (Sistema de Escore de Intervenção Terapêutica - TISS-28, usado em Unidades de Terapia Intensiva, um índice indireto para estimar intervalos de gravidade da doença que mais recentemente tem sido usado para relacionar a carga de trabalho de

  10. A Social Approach to Microfinance Credit Scoring

    OpenAIRE

    Serrano-Cinca, Carlos; Gutiérrez-Nieto, Begoña; Nydia M. Reyes

    2013-01-01

    Microfinance Institutions (MFIs) provide loans to low income individuals. The credit scoring systems of MFIs, if they exist, are strictly financial. Although many MFIs consider the social impact of their loans, they do not incorporate formal systems to estimate this social impact. This paper proposes that their creditworthiness evaluations should be coherent with their social mission and should, accordingly, estimate the social impact of microcredit. Thus, a decision support system to facilit...

  11. 基于.NET的排球成绩测评系统的设计与实现%Design and implementation of volleyball score evaluation system based on.NET

    Institute of Scientific and Technical Information of China (English)

    刘小豫; 韩丽娜

    2013-01-01

    To avoid the drawback of manual management mode in evaluation of volleyball scores of college physical educa-tion major students, a score evaluation system software for teachers was designed with the .NET framework and SQL database and the design scheme for score evaluation was achieved. It can realize automation score management of sports specialized stu-dents, which effectively solves the problem caused by manual mode. This system has the advantages of simple, scientific and convenient application. It improved the management level and work efficiency.%为了避免现有高校体育教育专业学生成绩测评时的手工管理方式,采用.NET框架和SQL Server数据库,设计了一个对体育专业大学生进行排球成绩测评的系统软件;获得了成绩测评的系统设计方案,以及大学生排球成绩的测评软件;采用.NET和SQL数据库结合的方法,能够实现体育专业学生成绩的自动化管理,有效方便地解决现有体育专业教师手工处理学生成绩测评问题,具有简单、科学且使用方便的特点,从而提高了管理水平和工作效率.

  12. The Machine Scoring of Writing

    Science.gov (United States)

    McCurry, Doug

    2010-01-01

    This article provides an introduction to the kind of computer software that is used to score student writing in some high stakes testing programs, and that is being promoted as a teaching and learning tool to schools. It sketches the state of play with machines for the scoring of writing, and describes how these machines work and what they do.…

  13. A Genomic Score Prognostic of Outcome in Trauma Patients

    OpenAIRE

    Warren, H. Shaw; Elson, Constance M; Hayden, Douglas L.; Schoenfeld, David A.; Cobb, J. Perren; Ronald V Maier; Moldawer, Lyle L; Moore, Ernest E; HARBRECHT, BRIAN G; Pelak, Kimberly; Cuschieri, Joseph; Herndon, David N; Jeschke, Marc G.; Finnerty, Celeste C.; Brownstein, Bernard H

    2009-01-01

    Traumatic injuries frequently lead to infection, organ failure, and death. Health care providers rely on several injury scoring systems to quantify the extent of injury and to help predict clinical outcome. Physiological, anatomical, and clinical laboratory analytic scoring systems (Acute Physiology and Chronic Health Evaluation [APACHE], Injury Severity Score [ISS]) are utilized, with limited success, to predict outcome following injury. The recent development of techniques for measuring the...

  14. The comparability of English, French and Dutch scores on the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F: an assessment of differential item functioning in patients with systemic sclerosis.

    Directory of Open Access Journals (Sweden)

    Linda Kwakkenbos

    Full Text Available OBJECTIVE: The Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F is commonly used to assess fatigue in rheumatic diseases, and has shown to discriminate better across levels of the fatigue spectrum than other commonly used measures. The aim of this study was to assess the cross-language measurement equivalence of the English, French, and Dutch versions of the FACIT-F in systemic sclerosis (SSc patients. METHODS: The FACIT-F was completed by 871 English-speaking Canadian, 238 French-speaking Canadian and 230 Dutch SSc patients. Confirmatory factor analysis was used to assess the factor structure in the three samples. The Multiple-Indicator Multiple-Cause (MIMIC model was utilized to assess differential item functioning (DIF, comparing English versus French and versus Dutch patient responses separately. RESULTS: A unidimensional factor model showed good fit in all samples. Comparing French versus English patients, statistically significant, but small-magnitude DIF was found for 3 of 13 items. French patients had 0.04 of a standard deviation (SD lower latent fatigue scores than English patients and there was an increase of only 0.03 SD after accounting for DIF. For the Dutch versus English comparison, 4 items showed small, but statistically significant, DIF. Dutch patients had 0.20 SD lower latent fatigue scores than English patients. After correcting for DIF, there was a reduction of 0.16 SD in this difference. CONCLUSIONS: There was statistically significant DIF in several items, but the overall effect on fatigue scores was minimal. English, French and Dutch versions of the FACIT-F can be reasonably treated as having equivalent scoring metrics.

  15. Research and development on an open performance scoring system of innovation inspiration platform of experimental courses%实验课创新激励平台开放式成绩评分系统研究与开发

    Institute of Scientific and Technical Information of China (English)

    樊树海; Amanda Elizabeth; 蒋南云; 方叶祥

    2011-01-01

    现行的实验课学生成绩评分体系比较封闭和僵化,开放性、创新性、差异性及时间性较差,不能适应研究型教学模式的开展.综合考虑实验课与相关理论课程的影响,鼓励实验创新,引入实验完成时间指标,改变成绩评判主观定性的弊病,提出了一种将贡献值反映到幂次上的实验课创新平台开放式成绩评分方案.结合升级模式,对其进行自动实现,以所见即所得的方式进行展示,活跃了教学气氛,也鼓励创新,充分调动了学生课后进行研究探索活动的积极性.%The current student's performance scoring system is rigid and closed.For the poor openness, innovation, otherness and timeliness, it does not fit for the research-oriented teaching mode.Therefore, an open performance scoring system of innovation inspiration platform of experimental courses is proposed, where student's contribution was adopted and reflected to the power function.This system has a comprehensive consideration for the mutual influence of experimental courses and theoretical teaching classes.It inspires the experimental innovation, adopts completion time indexes for experiments, and reduces some objective quantitative evaluation.Then the computation formula was deduced and the design scheme of the scoring system was also given.With the computerization, upgrading mode and a WYSWYG exhibition methods, this open performance scoring system was implemented.It brought forward an active classroom climate and extracurricular research activity.

  16. C语言程序设计课程积分制考核方式的改革与实践%Reform and practice of the score accumulation system examination method for C language programming course

    Institute of Scientific and Technical Information of China (English)

    王智群

    2016-01-01

    Aiming at the disadvantages of the existing in the college curriculum examination system, starting from the teaching of C language programming course, a student usual score accumulation evaluation system is adopted to practice, and the regression analysis and other statistical methods are used to analyze the data collected. The comparative test and analysis results show that there is a significant correlation between student's usual score accumulation and final exam grade and it is entirely feasible to replace student's final exam grade by usual score accumulation. Among the three inspection points of student usual score accumulation, i.e. the personal construction factor, the interactive construction factor and the situation construct factor, the personal construction factor plays a key role. Therefore, in the student usual score accumulation, the design and assessment of the personal construction factor should be increased, while the assessment of the situation construct factor, such as attendance etc., should be weakened.%针对普通高校课程考试制度中存在的诸多弊端,从C语言程序设计课程教学着手,采用平时积分制的考核方式进行实践,并使用回归分析等统计方法对收集的数据进行统计分析。对比试验和分析结果表明:学生的平时积分与期末考试成绩呈显著性相关关系,使用平时积分制取代期末考试成绩是完全可行的。在平时积分的个人建构因子、交互建构因子和情境建构因子三个考察点中,个人建构因子起关键性作用,因此在平时积分中要加大个人建构因子积分项目的设计和考核力度,淡化如出勤等情境建构因子的考核力度。

  17. Using Momentary Time Sampling to Estimate Minutes of Physical Activity in Physical Education: Validation of Scores for the System for Observing Fitness Instruction Time

    Science.gov (United States)

    Heath, Edward M.; Coleman, Karen J.; Lensegrav, Tera L.; Fallon, Jennifer A.

    2006-01-01

    The System for Observing Fitness Instruction Time (SOFIT) is a direct observation system specifically developed for use during physical education (PE; McKenzie, 1991; McKenzie, Sallis, & Nader, 1991). The purpose of this study was to validate the estimates of time spent in various physical activity intensities obtained with the paper and pencil…

  18. Obstetrical disseminated intravascular coagulation score.

    Science.gov (United States)

    Kobayashi, Takao

    2014-06-01

    Obstetrical disseminated intravascular coagulation (DIC) is usually a very acute, serious complication of pregnancy. The obstetrical DIC score helps with making a prompt diagnosis and starting treatment early. This DIC score, in which higher scores are given for clinical parameters rather than for laboratory parameters, has three components: (i) the underlying diseases; (ii) the clinical symptoms; and (iii) the laboratory findings (coagulation tests). It is justifiably appropriate to initiate therapy for DIC when the obstetrical DIC score reaches 8 points or more before obtaining the results of coagulation tests. Improvement of blood coagulation tests and clinical symptoms are essential to the efficacy evaluation for treatment after a diagnosis of obstetrical DIC. Therefore, the efficacy evaluation criteria for obstetrical DIC are also defined to enable follow-up of the clinical efficacy of DIC therapy.

  19. 平衡记分卡在临床科室绩效考核指标体系中的应用%Application of the Balanced Score Card in Performance Assessment Index System for Clinical Departments of Hospital

    Institute of Scientific and Technical Information of China (English)

    刘瑞敏; 贺延平; 徐劲松; 呼子涵

    2012-01-01

    目的 建立科学合理的临床科室绩效评价指标体系.方法 参考文献,利用德尔菲法确定医院临床科室绩效评价的三级指标体系及权重.结果 构建了一套较为科学实用的临床科室平衡计分卡绩效评价指标体系.该体系包括4个一级指标,10个二级指标,26个三级指标.结论 平衡计分卡从多个维度评价科室,有利于发现科室的不足,并持续改进.%Objective To establish scientific and rational performance assessment index system for clinical departments. Method Using the Delphi method to determine the tertiary index system and its weight for performance assessment of clinical departments in hospital. Result A more scientific and practical performance assessment index system with the Balanced Score Card was built, which included four primary indexes, ten secondary indexes and twenty - six third grade indexes. Conclusion The Balanced Score Card can evaluate medical work and development of clinical department in several aspects. It is beneficial to discover inadequacies of the clinical departments and can improve.

  20. From Rasch scores to regression

    DEFF Research Database (Denmark)

    Christensen, Karl Bang

    2006-01-01

    Rasch models provide a framework for measurement and modelling latent variables. Having measured a latent variable in a population a comparison of groups will often be of interest. For this purpose the use of observed raw scores will often be inadequate because these lack interval scale propertie....... This paper compares two approaches to group comparison: linear regression models using estimated person locations as outcome variables and latent regression models based on the distribution of the score....

  1. Inspection score and grading system for food services in Brazil: the results of a food safety strategy to reduce the risk of foodborne diseases during the 2014 FIFA World Cup

    Directory of Open Access Journals (Sweden)

    Diogo Thimoteo Da Cunha

    2016-04-01

    Full Text Available In 2014, Brazil hosted one of the most popular sport competitions in the world, the FIFA World Cup. Concerned about the intense migration of tourists, the Brazilian government decided to deploy a food safety strategy based on inspection scores and a grading system applied to food services. The present study aimed to evaluate the results of the food safety strategy deployed during the 2014 FIFA World Cup in Brazil. To assess food safety, an evaluation instrument was applied twice in 1927 food service establishments from 26 cities before the start of the competition. This instrument generated a food safety score for each establishment that ranged from 0.0 (no flaws observed to 2565.95, with four possible grades: A (0.0 to 13.2; B (13.3 to 502.6; C (502.7 to 1152.2; and pending (more than 1152.3. Each food service received a stamp with the grade of the second evaluation. After the end of the World Cup, a study was conducted with different groups of the public to evaluate the acceptance of the strategy. To this end, 221 consumers, 998 food service owners or managers, 150 health surveillance auditors and 27 health surveillance coordinators were enrolled. These participants completed a survey with positive and negative responses about the inspection score system through a 5-point Likert scale. A reduction in violation scores from 393.1 to 224.4 (p <0.001 was observed between the first and second evaluation cycles. Of the food services evaluated, 38.7% received the A stamp, 41.4% the B stamp and 13.9% the C stamp. All positive responses on system reliability presented a mean of 4.0 or more, indicating that the public believed this strategy is reliable for communicating risks and promoting food safety. The strategy showed positive results regarding food safety and public acceptance. The deployed strategy promoted improvements in the food safety of food services. The implementation of a permanent policy may be well accepted by the public and may greatly

  2. Inspection Score and Grading System for Food Services in Brazil: The Results of a Food Safety Strategy to Reduce the Risk of Foodborne Diseases during the 2014 FIFA World Cup.

    Science.gov (United States)

    da Cunha, Diogo T; Saccol, Ana L de Freitas; Tondo, Eduardo C; de Oliveira, Ana B A; Ginani, Veronica C; Araújo, Carolina V; Lima, Thalita A S; de Castro, Angela K F; Stedefeldt, Elke

    2016-01-01

    In 2014, Brazil hosted one of the most popular sport competitions in the world, the FIFA World Cup. Concerned about the intense migration of tourists, the Brazilian government decided to deploy a food safety strategy based on inspection scores and a grading system applied to food services. The present study aimed to evaluate the results of the food safety strategy deployed during the 2014 FIFA World Cup in Brazil. To assess food safety, an evaluation instrument was applied twice in 1927 food service establishments from 26 cities before the start of the competition. This instrument generated a food safety score for each establishment that ranged from 0.0 (no flaws observed) to 2565.95, with four possible grades: A (0.0-13.2); B (13.3-502.6); C (502.7-1152.2); and pending (more than 1152.3). Each food service received a stamp with the grade of the second evaluation. After the end of the World Cup, a study was conducted with different groups of the public to evaluate the acceptance of the strategy. To this end, 221 consumers, 998 food service owners or managers, 150 health surveillance auditors, and 27 health surveillance coordinators were enrolled. These participants completed a survey with positive and negative responses about the inspection score system through a 5-point Likert scale. A reduction in violation scores from 393.1 to 224.4 (p < 0.001) was observed between the first and second evaluation cycles. Of the food services evaluated, 38.7% received the A stamp, 41.4% the B stamp, and 13.9% the C stamp. All positive responses on "system reliability" presented a mean of 4.0 or more, indicating that the public believed this strategy is reliable for communicating risks and promoting food safety. The strategy showed positive results regarding food safety and public acceptance. The deployed strategy promoted improvements in the food safety of food services. The implementation of a permanent policy may be well accepted by the public and may greatly contribute to a

  3. Inspection Score and Grading System for Food Services in Brazil: The Results of a Food Safety Strategy to Reduce the Risk of Foodborne Diseases during the 2014 FIFA World Cup.

    Science.gov (United States)

    da Cunha, Diogo T; Saccol, Ana L de Freitas; Tondo, Eduardo C; de Oliveira, Ana B A; Ginani, Veronica C; Araújo, Carolina V; Lima, Thalita A S; de Castro, Angela K F; Stedefeldt, Elke

    2016-01-01

    In 2014, Brazil hosted one of the most popular sport competitions in the world, the FIFA World Cup. Concerned about the intense migration of tourists, the Brazilian government decided to deploy a food safety strategy based on inspection scores and a grading system applied to food services. The present study aimed to evaluate the results of the food safety strategy deployed during the 2014 FIFA World Cup in Brazil. To assess food safety, an evaluation instrument was applied twice in 1927 food service establishments from 26 cities before the start of the competition. This instrument generated a food safety score for each establishment that ranged from 0.0 (no flaws observed) to 2565.95, with four possible grades: A (0.0-13.2); B (13.3-502.6); C (502.7-1152.2); and pending (more than 1152.3). Each food service received a stamp with the grade of the second evaluation. After the end of the World Cup, a study was conducted with different groups of the public to evaluate the acceptance of the strategy. To this end, 221 consumers, 998 food service owners or managers, 150 health surveillance auditors, and 27 health surveillance coordinators were enrolled. These participants completed a survey with positive and negative responses about the inspection score system through a 5-point Likert scale. A reduction in violation scores from 393.1 to 224.4 (p second evaluation cycles. Of the food services evaluated, 38.7% received the A stamp, 41.4% the B stamp, and 13.9% the C stamp. All positive responses on "system reliability" presented a mean of 4.0 or more, indicating that the public believed this strategy is reliable for communicating risks and promoting food safety. The strategy showed positive results regarding food safety and public acceptance. The deployed strategy promoted improvements in the food safety of food services. The implementation of a permanent policy may be well accepted by the public and may greatly contribute to a reduction in foodborne diseases (FBDs).

  4. Inspection Score and Grading System for Food Services in Brazil: The Results of a Food Safety Strategy to Reduce the Risk of Foodborne Diseases during the 2014 FIFA World Cup

    Science.gov (United States)

    da Cunha, Diogo T.; Saccol, Ana L. de Freitas; Tondo, Eduardo C.; de Oliveira, Ana B. A.; Ginani, Veronica C.; Araújo, Carolina V.; Lima, Thalita A. S.; de Castro, Angela K. F.; Stedefeldt, Elke

    2016-01-01

    In 2014, Brazil hosted one of the most popular sport competitions in the world, the FIFA World Cup. Concerned about the intense migration of tourists, the Brazilian government decided to deploy a food safety strategy based on inspection scores and a grading system applied to food services. The present study aimed to evaluate the results of the food safety strategy deployed during the 2014 FIFA World Cup in Brazil. To assess food safety, an evaluation instrument was applied twice in 1927 food service establishments from 26 cities before the start of the competition. This instrument generated a food safety score for each establishment that ranged from 0.0 (no flaws observed) to 2565.95, with four possible grades: A (0.0–13.2); B (13.3–502.6); C (502.7–1152.2); and pending (more than 1152.3). Each food service received a stamp with the grade of the second evaluation. After the end of the World Cup, a study was conducted with different groups of the public to evaluate the acceptance of the strategy. To this end, 221 consumers, 998 food service owners or managers, 150 health surveillance auditors, and 27 health surveillance coordinators were enrolled. These participants completed a survey with positive and negative responses about the inspection score system through a 5-point Likert scale. A reduction in violation scores from 393.1 to 224.4 (p < 0.001) was observed between the first and second evaluation cycles. Of the food services evaluated, 38.7% received the A stamp, 41.4% the B stamp, and 13.9% the C stamp. All positive responses on “system reliability” presented a mean of 4.0 or more, indicating that the public believed this strategy is reliable for communicating risks and promoting food safety. The strategy showed positive results regarding food safety and public acceptance. The deployed strategy promoted improvements in the food safety of food services. The implementation of a permanent policy may be well accepted by the public and may greatly

  5. 滑雪比赛计时计分系统车载移动显示屏的研制%Developing the Vehicle-Carried Moble LED for Skiing Competition Timing & Scoring System

    Institute of Scientific and Technical Information of China (English)

    曹军

    2011-01-01

    As a fire-new research filed for developing Chinese skiing competition equipment industry,the vehicle-carried moble LED for skiing competition timing scoring system is a new LED product of being applied in skiing competition timing and scoring field.The paper discusses the system's feasible framework and implement method and the problems of its main parts' design,work and usage.The purpose is to put forward a possibility of developing the standardization of vehicle-carried moble LED for winter ice-snow sports competition timing and scoring system.%滑雪比赛计时计分系统车载移动显示屏,是一种新型专用于滑雪比赛计时计分功能的LED应用产品,是为推动我国滑雪比赛装备产业的进步与发展而提出的一个全新的研发领域。通过讨论可应用于滑雪比赛计时计分的大型车载LED显示及控制系统的构架、实现的方法及各部分的设计、工作与使用,旨在探讨建立标准化的冬季冰雪运动比赛计时计分车载移动显示及控制系统的可能性。

  6. SCORING IN ACUTE PANCREATITIS: WHEN IMAGING IS APPROPRIATE?.

    Science.gov (United States)

    Cucuteanu, B; Prelipcean, Cristina Cijevschi; Mihai, Cătălina; Dranga, Mihaela; Negru, D

    2016-01-01

    Acute pancreatitis (AP) is a frequent presentation to the emergency departments with a rising incidence and a great variability in clinical severity and outcome. The aim of this review is to offer a succinct presentation on acute pancreatitis scoring systems and the use of different imaging methods in severity prediction: Ranson criteria, Glasgow criteria, Hong Kong Score, Acute Physiology and Chronic Health Evaluation II (APACHE II), computed tomography scoring systems, Bedside Index of Severity in Acute Pancreatitis (BISAP) score, Panc 3, Japanese Severity Score (JSS), Harmless Acute Pancreatitis Score (HAPS), Pancreatitis Outcome Prediction (POP), Sequential Organ Failure Assessment (SOFA). This article also describes the Revised Atlanta Classification of AP (2012) and the correlation with computed tomography.

  7. English Automated Essay Scoring System Application Research Based on Semantic Web Technology%基于语义网技术的英语作文自动评判应用研究

    Institute of Scientific and Technical Information of China (English)

    谢少华

    2012-01-01

    本文首先评介国内外具有代表性的作文自动评分系统,介绍语义网的相关概念及特点;然后分析语义网技术如何应用于英语作文自动评判系统及构建实施方案流程图;最后展望该技术应用于中国英语学习者作文自动评分所面临的问题和发展前景。%This paper first reviews representative automated essay scoring system at home and abroad,introduces the concept and characteristics of the semantic web;then analyze how semantic web technologies used in automated assessment system for English composition and build embodiment flowchart;Finally,the future of the technology in China,English learners' automated essay scoring face the problems and prospects for development.

  8. Ligand Identification Scoring Algorithm (LISA)

    Science.gov (United States)

    Zheng, Zheng; Merz, Kenneth M.

    2011-01-01

    A central problem in de novo drug design is determining the binding affinity of a ligand with a receptor. A new scoring algorithm is presented that estimates the binding affinity of a protein-ligand complex given a three-dimensional structure. The method, LISA (Ligand Identification Scoring Algorithm), uses an empirical scoring function to describe the binding free energy. Interaction terms have been designed to account for van der Waals (VDW) contacts, hydrogen bonding, desolvation effects and metal chelation to model the dissociation equilibrium constants using a linear model. Atom types have been introduced to differentiate the parameters for VDW, H-bonding interactions and metal chelation between different atom pairs. A training set of 492 protein-ligand complexes was selected for the fitting process. Different test sets have been examined to evaluate its ability to predict experimentally measured binding affinities. By comparing with other well known scoring functions, the results show that LISA has advantages over many existing scoring functions in simulating protein-ligand binding affinity, especially metalloprotein-ligand binding affinity. Artificial Neural Network (ANN) was also used in order to demonstrate that the energy terms in LISA are well designed and do not require extra cross terms. PMID:21561101

  9. [Intraoperative crisis and surgical Apgar score].

    Science.gov (United States)

    Oshiro, Masakatsu; Sugahara, Kazuhiro

    2014-03-01

    Intraoperative crisis is an inevitable event to anesthesiologists. The crisis requires effective and coordinated management once it happened but it is difficult to manage the crises properly under extreme stressful situation. Recently, it is reported that the use of surgical crisis checklists is associated with significant improvement in the management of operating-room crises in a high-fidelity simulation study. Careful preoperative evaluation, proper intraoperative management and using intraoperative crisis checklists will be needed for safer perioperative care in the future. Postoperative complication is a serious public health problem. It reduces the quality of life of patients and raises medical cost. Careful management of surgical patients is required according to their postoperative condition for preventing postoperative complications. A 10-point surgical Apgar score, calculated from intraoperative estimated blood loss, lowest mean arterial pressure, and lowest heart rate, is a simple and available scoring system for predicting postoperative complications. It undoubtedly predicts higher than average risk of postoperative complications and death within 30 days of surgery. Surgical Apgar score is a bridge between proper intraoperative and postoperative care. Anesthesiologists should make effort to reduce the postoperative complication and this score is a tool for it.

  10. MRI interrReader and intra-reader reliabilities for assessing injury morphology and posterior ligamentous complex integrity of the spine according to the thoracolumbar injury classification system and severity score

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Guen Young; Lee, Joon Woo; Choi, Seung Woo; Lim, Hyun Jin; Sun, Hye Young; Kang, Yu Suhn; Kang, Heung Sik [Dept. of Radiology, Seoul National University Bundang Hospital, Seongnam (Korea, Republic of); Chai, Jee Won; Kim, Su Jin [Dept. of Radiology, SMG-SNU Boramae Medical Center, Seoul (Korea, Republic of)

    2015-08-15

    To evaluate spine magnetic resonance imaging (MRI) inter-reader and intra-reader reliabilities using the thoracolumbar injury classification system and severity score (TLICS) and to analyze the effects of reader experience on reliability and the possible reasons for discordant interpretations. Six radiologists (two senior, two junior radiologists, and two residents) independently scored 100 MRI examinations of thoracolumbar spine injuries to assess injury morphology and posterior ligamentous complex (PLC) integrity according to the TLICS. Inter-reader and intra-reader agreements were determined and analyzed according to the number of years of radiologist experience. Inter-reader agreement between the six readers was moderate (k = 0.538 for the first and 0.537 for the second review) for injury morphology and fair to moderate (k = 0.440 for the first and 0.389 for the second review) for PLC integrity. No significant difference in inter-reader agreement was observed according to the number of years of radiologist experience. Intra-reader agreements showed a wide range (k = 0.538-0.822 for injury morphology and 0.423-0.616 for PLC integrity). Agreement was achieved in 44 for the first and 45 for the second review about injury morphology, as well as in 41 for the first and 38 for the second review of PLC integrity. A positive correlation was detected between injury morphology score and PLC integrity. The reliability of MRI for assessing thoracolumbar spinal injuries according to the TLICS was moderate for injury morphology and fair to moderate for PLC integrity, which may not be influenced by radiologist' experience.

  11. The Construction of Evaluation System of College Students Financial Assistance Based on the Balanced Score Card%基于平衡计分卡的高校学生资助评价体系构建研究

    Institute of Scientific and Technical Information of China (English)

    赵健

    2014-01-01

    为推动高校贫困学生资助体系科学化,提出了构建高校平衡计分卡学生资助体系的设计原理、主要特点、战略地图、关键指标、实施要项等,并进行了可行性、必要性分析。%T he construction of university students'financial aiding evaluation system based on the bal‐anced score card (BSC) is analyzed from aspects of designing principles ,main features ,the strategic map , key indexes ,important implementation approaches ,etc .T he feasibility and necessity of the system are then discussed .

  12. Interpreting Force Concept Inventory Scores: Normalized Gain and SAT Scores

    Science.gov (United States)

    Coletta, Vincent P.; Phillips, Jeffrey A.; Steinert, Jeffrey J.

    2007-01-01

    Preinstruction SAT scores and normalized gains (G) on the force concept inventory (FCI) were examined for individual students in interactive engagement (IE) courses in introductory mechanics at one high school (N=335) and one university (N=292), and strong, positive correlations were found for both populations (r=0.57 and r=0.46, respectively).…

  13. A Vocal Password System Based on Multi-Dimension Feature Classifier in Score Domain%基于得分域多维特征分类器的声纹密码系统

    Institute of Scientific and Technical Information of China (English)

    潘逸倩; 魏思; 戴礼荣; 刘庆峰

    2012-01-01

    As providing the score of different types of data the same weight, the average likelihood ratio verification measure used in GMM-UBM vocal password system brings decline in the system performance. Based on the different distinguished capacity between data types, a method is proposed in the score domain which classifies the test data by UBM, combines the likelihood ratio score of each class to form new multi-dimension feature, and then implements speaker verification by SVM. By use of the proposed strategy, the traditional likelihood ratio test is converted into a two-class classification problem in the multi-dimension feature space. The equal error rate of the proposed system is relatively 41. 25% , 33.33% , 37.49% and 26. 03% less than that of text-dependent GMM-UBM system in the co-channel experiments on four telephone corpuses respectively. The improvement of performance is also demonstrated through the cross-channel experiments.%针对不同类型数据对目标发音人区分能力不同的现象,在传统系统基础上提出利用UBM模型对测试数据进行分类,使用分类后的似然比得分形成多维特征,在此基础上利用SVM分类器进行声纹密码确认.该方法把传统的似然比检验策略转换成多维特征空间上的二类分类问题.测试与注册数据同信道情况时,在4种手机数据集上,文中系统相对文本相关GMM-UBM声纹密码系统等错误率分别下降41.25%、33.33%、37.49%和26.03%,在交叉信道上系统性能也获得改善.

  14. Building a Scoring Model for Small and Medium Enterprises

    Directory of Open Access Journals (Sweden)

    Răzvan Constantin CARACOTA

    2010-09-01

    Full Text Available The purpose of the paper is to produce a scoring model for small and medium enterprises seeking financing through a bank loan. To analyze the loan application, scoring system developed for companies is as follows: scoring quantitative factors and scoring qualitative factors. We have estimated the probability of default using logistic regression. Regression coefficients determination was made with a solver in Excel using five ratios as input data. Analyses and simulations were conducted on a sample of 113 companies, all accepted for funding. Based on financial information obtained over two years, 2007 and 2008, we could establishe and appreciate the default value.

  15. Aggregate exposure modelling of zinc pyrithione in rinse-off personal cleansing products using a person-orientated approach with market share refinement.

    Science.gov (United States)

    Tozer, Sarah A; Kelly, Seamus; O'Mahony, Cian; Daly, E J; Nash, J F

    2015-09-01

    Realistic estimates of chemical aggregate exposure are needed to ensure consumer safety. As exposure estimates are a critical part of the equation used to calculate acceptable "safe levels" and conduct quantitative risk assessments, methods are needed to produce realistic exposure estimations. To this end, a probabilistic aggregate exposure model was developed to estimate consumer exposure from several rinse off personal cleansing products containing the anti-dandruff preservative zinc pyrithione. The model incorporates large habits and practices surveys, containing data on frequency of use, amount applied, co-use along with market share, and combines these data at the level of the individual based on subject demographics to better estimate exposure. The daily-applied exposure (i.e., amount applied to the skin) was 3.79 mg/kg/day for the 95th percentile consumer. The estimated internal dose for the 95th percentile exposure ranged from 0.01-1.29 μg/kg/day after accounting for retention following rinsing and dermal penetration of ZnPt. This probabilistic aggregate exposure model can be used in the human safety assessment of ingredients in multiple rinse-off technologies (e.g., shampoo, bar soap, body wash, and liquid hand soap). In addition, this model may be used in other situations where refined exposure assessment is required to support a chemical risk assessment.

  16. A Bootstrap Procedure of Propensity Score Estimation

    Science.gov (United States)

    Bai, Haiyan

    2013-01-01

    Propensity score estimation plays a fundamental role in propensity score matching for reducing group selection bias in observational data. To increase the accuracy of propensity score estimation, the author developed a bootstrap propensity score. The commonly used propensity score matching methods: nearest neighbor matching, caliper matching, and…

  17. Estimating Decision Indices Based on Composite Scores

    Science.gov (United States)

    Knupp, Tawnya Lee

    2009-01-01

    The purpose of this study was to develop an IRT model that would enable the estimation of decision indices based on composite scores. The composite scores, defined as a combination of unidimensional test scores, were either a total raw score or an average scale score. Additionally, estimation methods for the normal and compound multinomial models…

  18. Avaliação da aplicabilidade de um modelo de credit scoring com varíaveis sistêmicas e não-sistêmicas em carteiras de crédito bancário rotativo de pessoas físicas An evaluation on the applicability of a credit scoring model, with systemic and non-systemic variables in revolving bank credit portfolio for individuals

    Directory of Open Access Journals (Sweden)

    José Odálio dos Santos

    2007-08-01

    capability. Likewise, a more significant historical exposition of the banks to insolvency risk is being observed, such as the risk of not getting paid (partially or totally and the revolving credit borrowed by consumers. Considering the size and the importance of this market to the great commercial banks and to the economy as a whole, the scope of this research comprises the following points: 1. detailing the processes of subjective and objective credit analysis carried out by the main domestic private banks; 2. approaching the selective function of interest rates in revolving credits; 3. highlighting the main characteristics of credit scoring models; and 4. proposing a model of credit scoring for revolving credits. This model is based on systemic and non-systemic variables and directed to the reduction of insolvency risk. The applicability of the credit scoring model proposed in a sample, extracted from the consumers credit portfolio which belongs to an important medium size Brazilian private commercial bank (Bank X - fictitious name, presented a satisfactory accuracy level in the identification of prospective (96% and non-prospective (92% clients, which led to the conclusion that it included and considered adequately the representative variables of borrowers’ payment capability.

  19. EXPLORACIÓN DE DIFERENCIAS NORMATIVAS EN EL SISTEMA DE CALIFICACIÓN CUALITATIVA PARA EL TEST GESTÁLTICO DE BENDER MODIFICADO/ EXPLORING NORMATIVE DIFFERENCES IN QUALITATIVE SCORING SYSTEM FOR MODIFIED THE BENDER GESTALT TEST

    Directory of Open Access Journals (Sweden)

    César Merino Soto*

    2011-09-01

    Full Text Available RESUMENEl presente estudio explora la magnitud de las diferencias en los puntajes del Sistema de Calificación Cualitativa parael Test Gestáltico de Bender Modificado, usando diferente información normativa proveniente de Perú, Estados Unidos yChina. En una muestra de 324 niños(as peruanos entre 5 y 6 años de edad, se analizaron las potenciales diferencias en ladensidad, tendencia central, dispersión y clasificaciones de rendimiento visomotor. Se hallaron grandes diferenciasnormativas, y por lo tanto, el desempeño en los participantes se vio altamente sobreestimado o subestimado dependiendode la norma usada. Se discute el impacto de estos resultados en la apropiada práctica evaluativa en niños.ABSTRACTThis study explores the magnitude of difference in scores from Qualitative Scoring System to Bender Gestalt TestModified using different normative data from Peru, USA and China. In a sample of 324 children (boys and girls between5 and 6 ages, we analyzed the potential differences in density, central tendency, dispersion and visual motor performanceclassifications. It was found large normative differences, and therefore, performance in participants was highlyoverestimated or underestimated depending on the standard used. It discusses the impact of these results in the appropriateassessment practice in children.

  20. 基于单片机的划线冲点一体机控制系统设计%Design of scoring-drilling machine's control system based on singlechip computer

    Institute of Scientific and Technical Information of China (English)

    陈丽萍; 胡礼广

    2011-01-01

    针对一体机划线、冲点等功能的需要,结合该控制系统的组成、硬件电路的设计及控制流程,设计了单片机控制下的自动化控制系统。该系统总的生产制造成本低,在实际应用中效果良好,大大提高了生产的划线冲点效率。%In view of scoring-drilling's needs of a body machine, we combine the control system's composition and hardware circuit's principle and process. The singlechip computer based automatic control system is designed herein. The system's total manufacturing cost is low, and its effect is good in the practical application. It improved the scoring-drilling efficiency of the production lineation greatly.

  1. Anterior Cruciate Ligament OsteoArthritis Score (ACLOAS)

    DEFF Research Database (Denmark)

    Roemer, Frank W; Frobell, Richard; Lohmander, Stefan;

    2014-01-01

    OBJECTIVE: To develop a whole joint scoring system, the Anterior Cruciate Ligament OsteoArthritis Score (ACLOAS), for magnetic resonance imaging (MRI)-based assessment of acute anterior cruciate ligament (ACL) injury and follow-up of structural sequelae, and to assess its reliability. DESIGN...

  2. Night cough counts and diary card scores in asthma.

    OpenAIRE

    Archer, L N; Simpson, H

    1985-01-01

    A tape recording system for recording night cough in asthmatics at home is described. Objective cough counts and half hour periods containing cough did not correlate with diary card scores awarded to eight children on seven nights each. Night cough diary scores may mislead in the assessment of symptom severity.

  3. Content Influence While Stage Scoring Moral Thought Statements

    Science.gov (United States)

    Napier, John D.

    1977-01-01

    Two types of test scores were analyzed to examine whether sixty teachers were unable to use Kohlberg's measurement system for determining stages of moral thought because they were stage scoring invalidly on the basis of content. This proved to be the case. (Author/JKS)

  4. Nine equivalents of nursing manpower use score (NEMS)

    NARCIS (Netherlands)

    Miranda, DR; Moreno, R; Iapichino, G

    1997-01-01

    Objectives:To develop a simplified Therapeutic Intervention Scoring System (TISS) based on the TISS-28 items and to validate the new score in an independent dat abase. Design: Retrospective statistical analysis of a database and a prospective multicentre study. Setting: Development in the data base

  5. 不同评分系统对急性胰腺炎患者预后评估的比较%Comparative study on different clinical scoring systems in the prognosis of acute pancreatitis

    Institute of Scientific and Technical Information of China (English)

    林孙龙

    2014-01-01

    目的:比较急性胰腺炎严重程度的床边指数(BISAP)、Ranson评分和Balthazar CT严重度指数(CTSI)在急性胰腺炎(AP)预后评估中的价值。方法采用回顾性分析的研究方法,选取2011年5月至2013年5月我科收治的62例AP患者为研究对象,分别采用BISAP、Ranson、CTSI评分评估患者的预后,受试者工作曲线(ROC)分析三种评分系统的临床价值。结果62例AP患者中轻型AP 50例,重型AP 12例;26例患者出现并发症,6例多器官衰竭者,死亡10例,死亡率为16.1%,三种评分系统预测轻、重型AP差异无统计学意义(P>0.05)。BISAP评分在并发症、多器官功能障碍综合征(MODS)以及死亡的预判中最佳约登指数最大,显著高于Ranson评分和CTSI评分(P0.05). BISAP had highest Youden index and CTSI. BISAP score had a higher ability in predicting systemic complica-tions, MODS and death rate, compared to Ranson and CTSI scores (P<0.05). Conclusion BISAP, Ranson, and CTSI score systems all have important values in predicting the severity of acute pancreatitis (AP), But BISAP has a higher ability in the prediction of local complications, systemic complications, MODS, and mortality.

  6. LSAT Scores of Economics Majors.

    Science.gov (United States)

    Nieswiadomy, Michael

    1998-01-01

    Argues that economics education provides many benefits to students, including preparation for law school. Examines the ranking of economics majors on the Law School Admission Test (LSAT). Finds that among the 14 majors having more than 2,000 students take the LSAT, economics students received the highest average score. (DSK)

  7. The persistence of depression score

    NARCIS (Netherlands)

    Spijker, J.; de Graaf, R.; Ormel, J.; Nolen, W. A.; Grobbee, D. E.; Burger, H.

    2006-01-01

    Objective: To construct a score that allows prediction of major depressive episode (MDE) persistence in individuals with MDE using determinants of persistence identified in previous research. Method: Data were derived from 250 subjects from the general population with new MDE according to DSM-III-R.

  8. Bedside noninvasive scoring system in diagnosis of coronary heart disease%床旁无创积分法用于初步诊断冠心病的临床研究

    Institute of Scientific and Technical Information of China (English)

    张灿秀; 肖喜刚; 王岚峰; 潘薇; 刘洪仁; 黄永麟

    2012-01-01

    目的 评价床旁无创积分法初步诊断冠心病的有效性.方法 2008年9月至2010年10月入选我院612例疑诊冠心病患者(男性343例,女性269例),平均年龄(55±7)岁.对所有患者均详细询问病史和体格检查并检查静息心电图、血生化、平板运动试验和(或)12导联动态心电图,同时进行64排或256排冠状动脉CT成像检查或冠状动脉造影.采用Delphi法,通过对专家多次问卷调查筛选出评价冠心病可能性的临床指标(性别、年龄、吸烟史、饮酒史、高血压病、高脂血症、糖尿病、典型胸痛及心电图、平板运动试验或动态心电图等);依据专家做出的危险分层、判断依据水平和熟悉程度量化各指标,其中大量吸烟、糖尿病、典型胸痛、平板运动试验阳性和动态心电图阳性为极高危,积8分;三项血脂异常和合并左心室肥厚的高血压为高危,积6分;≥40岁男性、中等量吸烟、两项血脂异常、血糖异常、大量饮酒、心电图阳性和绝经后女性为中危,积4分;少量饮酒和一项血脂异常为低危,积2分.对所有患者进行床旁无创积分法评价,并与多排螺旋CT或冠状动脉造影结果比较,评价该积分法的价值.结果 积分≥24用于初步诊断冠心病标准的敏感性为89.95%,特异性为85.63%,阳性预测值94.03%,但准确性为88.73%.积分≤14用于初步排除冠心病标准的敏感性为93.10%,特异性为82.86%,阴性预测值达98.09%,但准确性为84.80%.准确性均低于多排螺旋CT或冠状动脉造影(均P<0.05).结论 本床旁无创积分法可作为初筛冠心病的一种方法,且还有待进一步完善.%Objectives To evaluate the effectiveness of bedside noninvasive scoring system in diagnosis of coronary heart disease (CAD).Methods Six hundred and twelve patients with suspected CAD in our hospital were enrolled (343 males and 269 females) from September 2008 to October 2010,with an average

  9. Estudio transcultural con la prueba de Bender: Sistema de puntuación gradual (Cross-Cultural Study with Bender Test- Gradual Scoring System

    Directory of Open Access Journals (Sweden)

    Fabián Javier Marín Rueda

    2013-12-01

    Full Text Available RESUMEN: El objetivo del presente estudio es comparar el desempeño en la Prueba Gestáltica Visomotriz de Bender - Sistema de Puntuación Gradual (B-SPG en un grupo de niños peruanos en función a los datos ofrecidos por el manual brasilero de la prueba. Participaron 82 niños, de ambos sexos, con edades entre los 8 y 10 años (M = 9.21, DT = 0.83. Los niños provenían de los distritos de Pueblo Libre (43.9% y Rímac (51.2%, de la provincia de Lima, así como también de Lima Metropolitana (4.9%. El B-SPG fue aplicado de forma colectiva. Los promedios de puntos obtenidos por los niños peruanos en el B-SPG fueron significativamente superiores a los obtenidos por los niños brasileros en cada una de las edades estudiadas. Se destaca la importancia de investigar evidencias de validez y de confiabilidad para que la prueba pueda ser usada de forma adecuada en el Perú, considerando las particularidades de desarrollo de los niños del país. ABSTRACT: The objective of the study is to compare performance on the Bender Visual Motor Gestalt test - system of Gradual punctuation (B-SPG in a group of Peruvian children in connection with the data provided by the Brazilian manual of the test. In this research 82 Peruvian children were involved, both sexes, with ages between 8 and 10 years (M = 9.21, DT = 0.83. The hildren came from the districts of Pueblo Libre (43.9% and Rimac (51.2% in the province of Lima, as well as from metropolitan Lima (4.9%. The B-SPG was collectively applied in the children’s schools. The average points earned by the Peruvian children in the B-SPG were significantly higher than those obtained by Brazilian children in each one of the ages studied. It emphasizes the importance of investigating evidence of validity and reliability, so that, the test can be used appropriately in Peru, considering the peculiarities of the development of children in the country.

  10. Modelling the predictive performance of credit scoring

    Directory of Open Access Journals (Sweden)

    Shi-Wei Shen

    2013-02-01

    Full Text Available Orientation: The article discussed the importance of rigour in credit risk assessment.Research purpose: The purpose of this empirical paper was to examine the predictive performance of credit scoring systems in Taiwan.Motivation for the study: Corporate lending remains a major business line for financial institutions. However, in light of the recent global financial crises, it has become extremely important for financial institutions to implement rigorous means of assessing clients seeking access to credit facilities.Research design, approach and method: Using a data sample of 10 349 observations drawn between 1992 and 2010, logistic regression models were utilised to examine the predictive performance of credit scoring systems.Main findings: A test of Goodness of fit demonstrated that credit scoring models that incorporated the Taiwan Corporate Credit Risk Index (TCRI, micro- and also macroeconomic variables possessed greater predictive power. This suggests that macroeconomic variables do have explanatory power for default credit risk.Practical/managerial implications: The originality in the study was that three models were developed to predict corporate firms’ defaults based on different microeconomic and macroeconomic factors such as the TCRI, asset growth rates, stock index and gross domestic product.Contribution/value-add: The study utilises different goodness of fits and receiver operator characteristics during the examination of the robustness of the predictive power of these factors.

  11. Building and Application of Balanced Score Card in Hospital Management Information System%平衡计分卡在医院管理信息系统中的构建与应用

    Institute of Scientific and Technical Information of China (English)

    由宝剑; 肖笃; 田一宁

    2011-01-01

    The paper analyzed the application status of the Balanced Score Card management information system, put forward the general construction concept, and demonstrated the specific application details. BSC can be used to describe the hospital strategic planning, monitor operation of hospital and take performance assessment.%分析了平衡计分卡管理信息系统的应用现状,提出了总体构建思路,并详细介绍了具体应用情况.可利用平衡计分卡描绘医院战略规划,同时可对医院进行运营监控和绩效考核.

  12. 综合打分法在同仁医院眼科人才考核中的应用%The application of comprehensive scoring system at the ophthalmology department of Tongren Hospital

    Institute of Scientific and Technical Information of China (English)

    杜敬毅; 韩德民

    2011-01-01

    同仁医院眼科作为国家级重点学科,在评聘分开的小环境中,总结出一套较为科学、实用、可操作性较强的重点学科专业技术人员的考核办法是管理工作的当务之急.通过在日常管理工作中总结出来的综合打分法,运用该法对重点学科的高级职称人员的各项工作实施量化考核,以此来打造公开、公平和透明的竞争环境,促进重点学科各项工作的开展,打造有竞争力的人才队伍,提高公立医院的核心竞争力.%As a national key discipline. the Ophthalmology Department of Beijing Tongren Hospital this paper points out that competition in the market of ophthalmology is about competing for the best human resource. has been seeking a method that allows it to evaluate the practicing professionals in a more scientific, functional and feasible way against its policy of separating appointment from assessment. This paper discusses the “comprehensive scoring” system that the author has developed and applied in her daily managerial experiences. At the center of comprehensive scoring are quantitative evaluation of senior employees, and open and fair competition. Comprehensive scoring system has been proved effective in streamlining the management of a national key discipline, building competitive professional teams and improving the core competence of public hospitals.

  13. Design and Application of Usual Course Score Management System (UCSMS)--Taking Score Input and Browse as Example%平时课程成绩管理系统的设计与应用--以《输入和浏览成绩》为例

    Institute of Scientific and Technical Information of China (English)

    朴相珍

    2014-01-01

    本文中,利用 Visual FoxPro 语言编写了平时课程成绩管理系统。通过本系统,可以有效地掌握课堂纪律、轻松地实现平时课堂提问、非常方便地录入平时作业成绩以及期中考试成绩等功能,而且为学生查阅自己平时成绩和了解他人平时成绩提供了一种有用的工具。该系统的建立,有助于增强平时课堂教学中教师与学生间的互动、课堂气氛的活跃、课堂纪律的强化和课堂教学效率的提高,而且有助于调动学生的学习积极性,并能够真实地和公正地反映学生的平时成绩。%Based on Visual FoxPro programming language, a Usual Course Score Management System (UCSMS) was designed. Using UCSMS, multiple functions such as controlling classroom discipline, implementing classroom questioning, typing in mid-term and regular grades conveniently could be realized, and every students could roundly look into his/her and other student’s regular grades. The utilization of UCSMS can make the class atmosphere exciting, strengthen the class discipline, stimulate students’ learning enthusiasm, and also effectively enhance interactions between teachers and students, improve the class efficiency, and particularly reflect the truthfulness and justice of regular grades.

  14. Clinical value of a preoperative predictive scoring system for postoperative pancreatic fistula after pancreaticoduodenectomy%胰十二指肠切除术后胰瘘发生风险预测系统的临床价值

    Institute of Scientific and Technical Information of China (English)

    张倜; 李慧锴; 李强

    2013-01-01

    目的 探讨日本国立癌症中心医院(NCCH)建立的胰十二指肠切除术后胰瘘的术前预测系统(简称NCCH预测系统)的临床价值.方法 回顾性分析2008年10月至2012年1月天津医科大学附属肿瘤医院收治的100例术前诊断为壶腹周围肿瘤行胰十二指肠切除术患者的临床资料.NCCH预测系统纳入患者性别、胰腺癌、主胰管指数、门静脉受侵犯及腹腔内脂肪厚度5项指标,并将积分>4分者定义为术后胰瘘高危人群;≤4分者为低危人群.对影响术后胰瘘发生的相关因素采用Pearsonx2检验进行统计分析.应用ROC曲线分析NCCH预测系统对患者术后胰瘘发生的敏感度和特异度.结果 本组100例患者中,20例术后发生胰瘘,其中A级9例、B级6例、C级5例.相关因素分析结果表明:性别、胰腺癌、门静脉受侵犯、胰腺质地及胰肠吻合方式等与术后胰瘘的发生密切相关(x2=5.613,4.785,15.479,7.145,7.050,P<0.05).高危人群术后胰瘘发生率高达86.4% (19/22),而低危人群术后胰瘘发生率仅为1.3%(1/78),两者比较,差异有统计学意义(x2=77.637,P<0.05).ROC曲线分析表明:NCCH预测系统对术后胰瘘预测的敏感度、特异度分别达到95.0%和96.3%,ROC曲线下面积达99.0% (P <0.05).结论 NCCH预测系统能够准确地预测严重胰瘘的发生.%Objective To investigate the clinical value of a preoperative predictive scoring system established by National Cancer Center Hospital (NCCH) for postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD).Methods The clinical data of 100 patients with periampullary tumor who underwent PD in the Cancer Hospital of Tianjin Medical University from October 2008 to January 2012 were retrospectively analyzed.Five indexes including gender,pancreatic cancer,main pancreatic duct index,portal invasion and intra-abdominal fat thickness were in the NCCH preoperative predictive scoring system.Patients with score

  15. The Germinator automated germination scoring system

    OpenAIRE

    Joosen, R.V.L.; Kodde, J.; Willems, L. A. J.; Ligterink, W.; Hilhorst, H.W.M.

    2010-01-01

    Fundamental and applied seed biology research relies heavily on accurate quantification of seed germination. Nowadays, large-scale experiments using large genetic populations or mutant collections are popular tools to unravel the molecular aspects of seed development, germination, dormancy and seed performance. The scientific community has embraced Arabidopsis thaliana as the ultimate model species for plant science, and it has also become a very useful model plant to study seed biology. Howe...

  16. A Genomic Score Prognostic of Outcome in Trauma Patients

    Science.gov (United States)

    Warren, H Shaw; Elson, Constance M; Hayden, Douglas L; Schoenfeld, David A; Cobb, J Perren; Maier, Ronald V; Moldawer, Lyle L; Moore, Ernest E; Harbrecht, Brian G; Pelak, Kimberly; Cuschieri, Joseph; Herndon, David N; Jeschke, Marc G; Finnerty, Celeste C; Brownstein, Bernard H; Hennessy, Laura; Mason, Philip H; Tompkins, Ronald G

    2009-01-01

    Traumatic injuries frequently lead to infection, organ failure, and death. Health care providers rely on several injury scoring systems to quantify the extent of injury and to help predict clinical outcome. Physiological, anatomical, and clinical laboratory analytic scoring systems (Acute Physiology and Chronic Health Evaluation [APACHE], Injury Severity Score [ISS]) are utilized, with limited success, to predict outcome following injury. The recent development of techniques for measuring the expression level of all of a person’s genes simultaneously may make it possible to develop an injury scoring system based on the degree of gene activation. We hypothesized that a peripheral blood leukocyte gene expression score could predict outcome, including multiple organ failure, following severe blunt trauma. To test such a scoring system, we measured gene expression of peripheral blood leukocytes from patients within 12 h of traumatic injury. cRNA derived from whole blood leukocytes obtained within 12 h of injury provided gene expression data for the entire genome that were used to create a composite gene expression score for each patient. Total blood leukocytes were chosen because they are active during inflammation, which is reflective of poor outcome. The gene expression score combines the activation levels of all the genes into a single number which compares the patient’s gene expression to the average gene expression in uninjured volunteers. Expression profiles from healthy volunteers were averaged to create a reference gene expression profile which was used to compute a difference from reference (DFR) score for each patient. This score described the overall genomic response of patients within the first 12 h following severe blunt trauma. Regression models were used to compare the association of the DFR, APACHE, and ISS scores with outcome. We hypothesized that patients with a total gene response more different from uninjured volunteers would tend to have poorer

  17. Evidências de validade do bender: sistema de pontuação gradual (B-SPG Evidences of validity of bender: gradual scoring system (B-SPG

    Directory of Open Access Journals (Sweden)

    Ana Paula Porto Noronha

    2007-01-01

    Full Text Available Esse estudo objetivou buscar evidências de validade para o teste de Bender - Sistema de Pontuação Gradual (B-SPG, por meio da investigação das mudanças desenvolvimentais, expressas pela relação entre os escores com a idade. Fizeram parte do estudo 1052 crianças de oito escolas públicas estaduais e municipais de Campinas e região, de pré-escola à 4ª série do ensino fundamental. As idades variaram entre 6 e 10 anos, com uma média de 8,35 anos. Os achados revelaram que conforme aumentou a idade, diminuiu a pontuação obtida pelo B-SPG, indicando que com o aumento da idade, as distorções da cópia progressivamente diminuem. Embora outros estudos sejam recomendados, os resultados aqui apresentados estão em consonância com trabalhos que buscaram a constatação de que é possível encontrar um caráter maturacional nas figuras do teste.This study aimed to gather evidences of validity for the Bender test - Gradual Scoring System (B-SPG, investigating developmental changes based on the relationships between its scores and the ages of the children. The study investigated 1052 children attending from pre-school to fourth grade of eight municipal and state public schools of Campinas (a city in the state of São Paulo, Brazil and the surrounding region. Ages ranged from six to ten years old, with an average of 8,35. The findings indicated that according to the increase of age, the B-SPG scores diminished, suggesting that the distortions progressively diminish as the children become older. Although other studies are suggested, the results presented here are consonant with researches that sought to establish that it is possible too find a maturational character among the figures of the test.

  18. Research on Assisted Scoring System for Chinese Proficiency Test for Minorities%少数民族汉语考试的作文辅助评分系统研究

    Institute of Scientific and Technical Information of China (English)

    蔡黎; 彭星源; 赵军

    2011-01-01

    With the widespread application of computer and fast development of computer techonlogy,computer aided test and computer adopted test have turned into realization. Assisted essay scoring system (AES) have become the next generation of computer aided tools in people's expectation. Chinese AES is still in its infant stage. As we know that there is even no Chinese AES which can be widely used. We have done a lot of research on English AES. And we extracted some features described in the paper. However, the result was not promising. In this paper, we use the technology of statistical natural language processing and information retrieval to extract features. Then, we creatively integrate features such as the distribution of sample test score and a reviewer's score into statistical model, which we call triple segmented regression. The result is tremendous good. The experiment shows that using our AES, we can only use half of the labour force to get the precision above 97%.%随着计算机的普遍应用以及计算机技术的快速发展,计算机辅助性测试和计算机自适应性测试都已先后成为现实.计算机辅助评分,也称作计算机自动评分,就成为人们所希望的下一代计算机辅助工具.中文辅助评分系统的研究尚处于起步阶段,据我们了解还没有一个能大规模使用的系统.我们研究了许多英文的辅助评分系统,并按照文章中的算法提取特征,但是特征的相关度并不高.在该文中,我们利用统计自然语言处理和信息检索的技术提取作文写作水平和作文主题特征.在建模时,融入样本分数分布和一位评分员的评分的信息,创造性的提出三重分段回归模型.实验表明,利用我们的辅助评分系统协助评分,在节省一半阅卷重的情况下,精度可以达到97%以上.

  19. Interpreting force concept inventory scores: Normalized gain and SAT scores

    Directory of Open Access Journals (Sweden)

    Jeffrey J. Steinert

    2007-05-01

    Full Text Available Preinstruction SAT scores and normalized gains (G on the force concept inventory (FCI were examined for individual students in interactive engagement (IE courses in introductory mechanics at one high school (N=335 and one university (N=292 , and strong, positive correlations were found for both populations ( r=0.57 and r=0.46 , respectively. These correlations are likely due to the importance of cognitive skills and abstract reasoning in learning physics. The larger correlation coefficient for the high school population may be a result of the much shorter time interval between taking the SAT and studying mechanics, because the SAT may provide a more current measure of abilities when high school students begin the study of mechanics than it does for college students, who begin mechanics years after the test is taken. In prior research a strong correlation between FCI G and scores on Lawson’s Classroom Test of Scientific Reasoning for students from the same two schools was observed. Our results suggest that, when interpreting class average normalized FCI gains and comparing different classes, it is important to take into account the variation of students’ cognitive skills, as measured either by the SAT or by Lawson’s test. While Lawson’s test is not commonly given to students in most introductory mechanics courses, SAT scores provide a readily available alternative means of taking account of students’ reasoning abilities. Knowing the students’ cognitive level before instruction also allows one to alter instruction or to use an intervention designed to improve students’ cognitive level.

  20. Interpreting force concept inventory scores: Normalized gain and SAT scores

    Science.gov (United States)

    Coletta, Vincent P.; Phillips, Jeffrey A.; Steinert, Jeffrey J.

    2007-06-01

    Preinstruction SAT scores and normalized gains (G) on the force concept inventory (FCI) were examined for individual students in interactive engagement (IE) courses in introductory mechanics at one high school (N=335) and one university (N=292) , and strong, positive correlations were found for both populations ( r=0.57 and r=0.46 , respectively). These correlations are likely due to the importance of cognitive skills and abstract reasoning in learning physics. The larger correlation coefficient for the high school population may be a result of the much shorter time interval between taking the SAT and studying mechanics, because the SAT may provide a more current measure of abilities when high school students begin the study of mechanics than it does for college students, who begin mechanics years after the test is taken. In prior research a strong correlation between FCI G and scores on Lawson’s Classroom Test of Scientific Reasoning for students from the same two schools was observed. Our results suggest that, when interpreting class average normalized FCI gains and comparing different classes, it is important to take into account the variation of students’ cognitive skills, as measured either by the SAT or by Lawson’s test. While Lawson’s test is not commonly given to students in most introductory mechanics courses, SAT scores provide a readily available alternative means of taking account of students’ reasoning abilities. Knowing the students’ cognitive level before instruction also allows one to alter instruction or to use an intervention designed to improve students’ cognitive level.