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Sample records for class 1a dihydroorotate

  1. Mechanism of flavin reduction in the class 1A dihydroorotate dehydrogenase from Lactococcus lactis

    DEFF Research Database (Denmark)

    Fagan, Rebecca L; Jensen, Kaj Frank; Björnberg, Olof; Palfey, Bruce A

    2007-01-01

    is concerted or stepwise was addressed for the class 1A enzyme from Lactococcus lactis by determining kinetic isotope effects (KIEs) on flavin reduction in anaerobic stopped-flow experiments. Isotope effects were determined at two pH values. At pH 7.0, KIEs were approximately 2-fold for DHO labeled....... These isotope effects are consistent with a concerted oxidation of DHO. The pH dependence of reduction was also determined, and a pKa of 8.3 was found. This pKa can be attributed to the ionization of the active site cysteine which deprotonates C5 of DHO during the reaction. To further investigate the...... importance of the active site base, two site-directed mutants were also studied: Cys130Ala (removal of the active site base) and Cys130Ser (replacement with the active site base used by class 2 DHODs). Both mutant enzymes exhibited binding affinities for DHO similar to that of the wild-type enzyme. Reduction...

  2. Biochemical and molecular characterization of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase from Toxoplasma gondii

    OpenAIRE

    Triana, Miryam Andrea Hortua; Huynh, My-Hang; Manuel F Garavito; Fox, Barbara A.; Bzik, David J.; Vern B Carruthers; Löffler, Monika; Zimmermann, Barbara H.

    2012-01-01

    The pyrimidine biosynthesis pathway in the protozoan pathogen Toxoplasma gondii is essential for parasite growth during infection. To investigate the properties of dihydroorotate dehydrogenase (TgDHOD), the fourth enzyme in the T. gondii pyrimidine pathway, we expressed and purified recombinant TgDHOD. TgDHOD exhibited a specific activity of 84 U/mg, a kcat of 89 sec−1, a Km = 60 μM for L-dihydroorotate, and a Km = 29 μM for decylubiquinone (QD). Quinones lacking or having short isoprenoid si...

  3. The Role of Dihydroorotate Dehydrogenase in Apoptosis Induction in Response to Inhibition of the Mitochondrial Respiratory Chain Complex III

    OpenAIRE

    Khutornenko, A.; Dalina, A.; Chernyak, B.; Chumakov, P; Evstafieva, A.

    2014-01-01

    A mechanism for the induction of programmed cell death (apoptosis) upon dysfunction of the mitochondrial respiratory chain has been studied. Previously, we had found that inhibition of mitochondrial cytochrome bc1, a component of the electron transport chain complex III, leads to activation of tumor suppressor p53, followed by apoptosis induction. The mitochondrial respiratory chain is coupled to the de novo pyrimidine biosynthesis pathway via the mitochondrial enzyme dihydroorotate dehydroge...

  4. Two different dihydroorotate dehydrogenases from yeast Saccharomyees kluyveri

    DEFF Research Database (Denmark)

    Zameitat, E.; Knecht, Wolfgang; Piskur, Jure; Loffler, M.

    2004-01-01

    Genes for two structurally and functionally different dihydroorotate dehydrogenases (DHODHs, EC 1.3.99.11), catalyzing the fourth step of pyrimidine biosynthesis, have been previously found in yeast Saccharomyces klujveri. One is closely related to the Schizosaccharomyces pombe mitochondrial family...

  5. 32 CFR 1636.5 - Exclusion from Class 1-A-0 and Class 1-0.

    Science.gov (United States)

    2010-07-01

    ... participation in war does not rest at all upon moral, ethical, or religious principle, but instead rests solely... be excluded from Class 1-A-0 or Class 1-0: (a) Who asserts beliefs which are of a religious, moral...

  6. Structure of Dihydroorotate Dehydrogenase B: Electron Transfer between Two Flavin Groups Bridged by an Iron-Sulphur Cluster

    DEFF Research Database (Denmark)

    Rowland, Poul; Nørager, Sofie; Jensen, Kaj Frank; Larsen, Sine

    2000-01-01

    BACKGROUND: The fourth step and only redox reaction in pyrimidine de novo biosynthesis is catalyzed by the flavoprotein dihydroorotate dehydrogenase (DHOD). Based on their sequences, DHODs are grouped into two major families. Lactococcus lactis is one of the few organisms with two DHODs, A and B...... to the NADPH ferredoxin reductase superfamily. The binding site for NAD+ has been deduced from the similarity to these proteins. The orotate binding in DHODB is similar to that in the family 1A enzymes. The close proximity of the three redox centers makes it possible to propose a possible electron...

  7. Structural Plasticity of Malaria Dihydroorotate Dehydrogenase Allows Selective Binding of Diverse Chemical Scaffolds

    International Nuclear Information System (INIS)

    Malaria remains a major global health burden and current drug therapies are compromised by resistance. Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) was validated as a new drug target through the identification of potent and selective triazolopyrimidine-based DHODH inhibitors with anti-malarial activity in vivo. Here we report x-ray structure determination of PfDHODH bound to three inhibitors from this series, representing the first of the enzyme bound to malaria specific inhibitors. We demonstrate that conformational flexibility results in an unexpected binding mode identifying a new hydrophobic pocket on the enzyme. Importantly this plasticity allows PfDHODH to bind inhibitors from different chemical classes and to accommodate inhibitor modifications during lead optimization, increasing the value of PfDHODH as a drug target. A second discovery, based on small molecule crystallography, is that the triazolopyrimidines populate a resonance form that promotes charge separation. These intrinsic dipoles allow formation of energetically favorable H-bond interactions with the enzyme. The importance of delocalization to binding affinity was supported by site-directed mutagenesis and the demonstration that triazolopyrimidine analogs that lack this intrinsic dipole are inactive. Finally, the PfDHODH-triazolopyrimidine bound structures provide considerable new insight into species-selective inhibitor binding in this enzyme family. Together, these studies will directly impact efforts to exploit PfDHODH for the development of anti-malarial chemotherapy.

  8. Biochemical and molecular characterization of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase from Toxoplasma gondii.

    Science.gov (United States)

    Hortua Triana, Miryam Andrea; Huynh, My-Hang; Garavito, Manuel F; Fox, Barbara A; Bzik, David J; Carruthers, Vern B; Löffler, Monika; Zimmermann, Barbara H

    2012-08-01

    The pyrimidine biosynthesis pathway in the protozoan pathogen Toxoplasma gondii is essential for parasite growth during infection. To investigate the properties of dihydroorotate dehydrogenase (TgDHOD), the fourth enzyme in the T. gondii pyrimidine pathway, we expressed and purified recombinant TgDHOD. TgDHOD exhibited a specific activity of 84U/mg, a k(cat) of 89s(-1), a K(m)=60μM for l-dihydroorotate, and a K(m)=29μM for decylubiquinone (Q(D)). Quinones lacking or having short isoprenoid side chains yielded lower k(cat)s than Q(D). As expected, fumarate was a poor electron acceptor for this family 2 DHOD. The IC(50)s determined for A77-1726, the active derivative of the human DHOD inhibitor leflunomide, and related compounds MD249 and MD209 were, 91μM, 96μM, and 60μM, respectively. The enzyme was not significantly affected by brequinar or TTFA, known inhibitors of human DHOD, or by atovaquone. DSM190, a known inhibitor of Plasmodium falciparum DHOD, was a poor inhibitor of TgDHOD. TgDHOD exhibits a lengthy 157-residue N-terminal extension, consistent with a potential organellar targeting signal. We constructed C-terminally c-myc tagged TgDHODs to examine subcellular localization of TgDHOD in transgenic parasites expressing the tagged protein. Using both exogenous and endogenous expression strategies, anti-myc fluorescence signal colocalized with antibodies against the mitochondrial marker ATPase. These findings demonstrate that TgDHOD is associated with the parasite's mitochondrion, revealing this organelle as the site of orotate production in T. gondii. The TgDHOD gene appears to be essential because while gene tagging was successful at the TgDHOD gene locus, attempts to delete the TgDHOD gene were not successful in the KU80 background. Collectively, our study suggests that TgDHOD is an excellent target for the development of anti-Toxoplasma drugs. PMID:22580100

  9. Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans

    DEFF Research Database (Denmark)

    Zameitat, E.; Gojkovic, Zoran; Knecht, Wolfgang;

    2006-01-01

    Candida albicans is the most prevalent yeast pathogen in humans, and recently it has become increasingly resistant to the current antifungal agents. In this study we investigated C. albicans dihydroorotate dehydrogenase (DHODH, EC 1.3.99.11), which catalyzes the fourth step of de novo pyrimidine ...

  10. Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model*

    OpenAIRE

    Booker, Michael L.; Bastos, Cecilia M.; Kramer, Martin L.; Barker, Robert H.; Skerlj, Renato; Sidhu, Amar Bir; Deng, Xiaoyi; Celatka, Cassandra; Cortese, Joseph F.; Guerrero Bravo, Jose E.; Crespo Llado, Keila N.; Serrano, Adelfa E.; Angulo-Barturen, Iñigo; Jiménez-Díaz, María Belén; Viera, Sara

    2010-01-01

    Plasmodium falciparum, the causative agent of the most deadly form of human malaria, is unable to salvage pyrimidines and must rely on de novo biosynthesis for survival. Dihydroorotate dehydrogenase (DHODH) catalyzes the rate-limiting step in the pyrimidine biosynthetic pathway and represents a potential target for anti-malarial therapy. A high throughput screen and subsequent medicinal chemistry program identified a series of N-alkyl-5-(1H-benzimidazol-1-yl)thiophene-2-carboxamides with low ...

  11. Expression, purification and crystallization of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with orotate

    International Nuclear Information System (INIS)

    The Trypanosoma cruzi dihydroorotate dehydrogenase, a key enzyme in pyrimidine de novo biosynthesis and redox homeostasis, was crystallized in complex with its first reaction product, orotate. Dihydroorotate dehydrogenase (DHOD) catalyzes the oxidation of dihydroorotate to orotate, the fourth step and the only redox reaction in the de novo biosynthesis of pyrimidine. DHOD from Trypanosoma cruzi (TcDHOD) has been expressed as a recombinant protein in Escherichia coli and purified to homogeneity. Crystals of the TcDHOD–orotate complex were grown at 277 K by the sitting-drop vapour-diffusion technique using polyethylene glycol 3350 as a precipitant. The crystals diffract to better than 1.8 Å resolution using synchrotron radiation (λ = 0.900 Å). X-ray diffraction data were collected at 100 K and processed to 1.9 Å resolution with 98.2% completeness and an overall Rmerge of 7.8%. The TcDHOD crystals belong to the orthorhombic space group P212121, with unit-cell parameters a = 67.87, b = 71.89, c = 123.27 Å. The presence of two molecules in the asymmetric unit (2 × 34 kDa) gives a crystal volume per protein weight (VM) of 2.2 Å3 Da−1 and a solvent content of 44%

  12. Expression, purification and crystallization of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with orotate

    Energy Technology Data Exchange (ETDEWEB)

    Inaoka, Daniel Ken; Takashima, Eizo; Osanai, Arihiro; Shimizu, Hironari [Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Nara, Takeshi; Aoki, Takashi [Department of Parasitology, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421 (Japan); Harada, Shigeharu [Department of Applied Biology, Kyoto Institute of Technology, Sakyo-ku, Kyoto 606-8585 (Japan); Kita, Kiyoshi, E-mail: kitak@m.u-tokyo.ac.jp [Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan)

    2005-10-01

    The Trypanosoma cruzi dihydroorotate dehydrogenase, a key enzyme in pyrimidine de novo biosynthesis and redox homeostasis, was crystallized in complex with its first reaction product, orotate. Dihydroorotate dehydrogenase (DHOD) catalyzes the oxidation of dihydroorotate to orotate, the fourth step and the only redox reaction in the de novo biosynthesis of pyrimidine. DHOD from Trypanosoma cruzi (TcDHOD) has been expressed as a recombinant protein in Escherichia coli and purified to homogeneity. Crystals of the TcDHOD–orotate complex were grown at 277 K by the sitting-drop vapour-diffusion technique using polyethylene glycol 3350 as a precipitant. The crystals diffract to better than 1.8 Å resolution using synchrotron radiation (λ = 0.900 Å). X-ray diffraction data were collected at 100 K and processed to 1.9 Å resolution with 98.2% completeness and an overall R{sub merge} of 7.8%. The TcDHOD crystals belong to the orthorhombic space group P2{sub 1}2{sub 1}2{sub 1}, with unit-cell parameters a = 67.87, b = 71.89, c = 123.27 Å. The presence of two molecules in the asymmetric unit (2 × 34 kDa) gives a crystal volume per protein weight (V{sub M}) of 2.2 Å{sup 3} Da{sup −1} and a solvent content of 44%.

  13. Development of a human dihydroorotate dehydrogenase (hDHODH pharma-similarity index approach with scaffold-hopping strategy for the design of novel potential inhibitors.

    Directory of Open Access Journals (Sweden)

    Kuei-Chung Shih

    Full Text Available Human dihydroorotate dehydrogenase (hDHODH is a class-2 dihydroorotate dehydrogenase. Because it is extensively used by proliferating cells, its inhibition in autoimmune and inflammatory diseases, cancers, and multiple sclerosis is of substantial clinical importance. In this study, we had two aims. The first was to develop an hDHODH pharma-similarity index approach (PhSIA using integrated molecular dynamics calculations, pharmacophore hypothesis, and comparative molecular similarity index analysis (CoMSIA contour information techniques. The approach, for the discovery and design of novel inhibitors, was based on 25 diverse known hDHODH inhibitors. Three statistical methods were used to verify the performance of hDHODH PhSIA. Fischer's cross-validation test provided a 98% confidence level and the goodness of hit (GH test score was 0.61. The q(2, r(2, and predictive r(2 values were 0.55, 0.97, and 0.92, respectively, for a partial least squares validation method. In our approach, each diverse inhibitor structure could easily be aligned with contour information, and common substructures were unnecessary. For our second aim, we used the proposed approach to design 13 novel hDHODH inhibitors using a scaffold-hopping strategy. Chemical features of the approach were divided into two groups, and the Vitas-M Laboratory fragment was used to create de novo inhibitors. This approach provides a useful tool for the discovery and design of potential inhibitors of hDHODH, and does not require docking analysis; thus, our method can assist medicinal chemists in their efforts to identify novel inhibitors.

  14. The crystal structure of Lactococcus lactis dihydroorotate dehydrogenase A complexed with the enzyme reaction product throws light on its enzymatic function

    DEFF Research Database (Denmark)

    Rowland, Paul; Bjørnberg, Olof; Nielsen, Finn S.; Jensen, Kaj Frank; Larsen, Sine

    1998-01-01

    Dihydroorotate dehydrogenases (DHODs) catalyze the oxidation of (S)-dihydroorotate to orotate, the fourth step and only redox reaction in the de novo biosynthesis of pyrimidine nucleotides. A description is given of the crystal structure of Lactococcus lactis dihydroorotate dehydrogenase A (DHODA......) complexed with the product of the enzyme reaction orotate. The structure of the complex to 2.0 A resolution has been compared with the structure of the native enzyme. The active site of DHODA is known to contain a water filled cavity buried beneath a highly conserved and flexible loop. In the complex the...

  15. Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans

    DEFF Research Database (Denmark)

    Zameitat, E.; Gojkovic, Zoran; Knecht, Wolfgang; Piskur, Jure; Loffler, M.

    2006-01-01

    Candida albicans is the most prevalent yeast pathogen in humans, and recently it has become increasingly resistant to the current antifungal agents. In this study we investigated C. albicans dihydroorotate dehydrogenase (DHODH, EC 1.3.99.11), which catalyzes the fourth step of de novo pyrimidine...... lacks the targeting sequence and the transmembrane domain, were subcloned from C. albicans, recombinantly expressed in Escherichia coli, purified, and characterized for their kinetics and substrate specificity. An inhibitor screening with 28 selected compounds was performed. Only the dianisidine...... derivative, redoxal, and the biphenyl quinoline-carboxylic acid derivative, brequinar sodium, which are known to be potent inhibitors of mammalian DHODH, markedly reduced C. albicans DHODH activity. This study provides a background for the development of antipyrimidines with high efficacy for decreasing in...

  16. Site directed spin labeling studies of Escherichia coli dihydroorotate dehydrogenase N-terminal extension

    Energy Technology Data Exchange (ETDEWEB)

    Couto, Sheila G. [Instituto de Fisica de Sao Carlos, Universidade de Sao Paulo, Av. Trabalhador Sao-carlense 400, C.P. 369, 13560-970, Sao Carlos, SP (Brazil); Grupo de Biofisica e Fisica Aplicada a Medicina, Instituto de Fisica, Universidade Federal de Goias, Campus Samambaia, C.P. 131, 74001-970, Goiania, GO (Brazil); Cristina Nonato, M. [Laboratorio de Cristalografia de Proteinas, Faculdade de Ciencias Farmaceuticas de Ribeirao Preto, Universidade de Sao Paulo, Av. do Cafe S/N, 14040-903, Ribeirao Preto, SP (Brazil); Costa-Filho, Antonio J., E-mail: ajcosta@ffclrp.usp.br [Instituto de Fisica de Sao Carlos, Universidade de Sao Paulo, Av. Trabalhador Sao-carlense 400, C.P. 369, 13560-970, Sao Carlos, SP (Brazil); Departamento de Fisica, Faculdade de Filosofia, Ciencias e Letras de Ribeirao Preto, Av. Bandeirantes 3900, 14040-901, Ribeirao Preto, SP (Brazil)

    2011-10-28

    Highlights: Black-Right-Pointing-Pointer EcDHODH is a membrane-associated enzyme and a promising target for drug design. Black-Right-Pointing-Pointer Enzyme's N-terminal extension is responsible for membrane association. Black-Right-Pointing-Pointer N-terminal works as a molecular lid regulating access to the protein interior. -- Abstract: Dihydroorotate dehydrogenases (DHODHs) are enzymes that catalyze the fourth step of the de novo synthesis of pyrimidine nucleotides. In this reaction, DHODH converts dihydroorotate to orotate, using a flavine mononucleotide as a cofactor. Since the synthesis of nucleotides has different pathways in mammals as compared to parasites, DHODH has gained much attention as a promising target for drug design. Escherichia coli DHODH (EcDHODH) is a family 2 DHODH that interacts with cell membranes in order to promote catalysis. The membrane association is supposedly made via an extension found in the enzyme's N-terminal. In the present work, we used site directed spin labeling (SDSL) to specifically place a magnetic probe at positions 2, 5, 19, and 21 within the N-terminal and thus monitor, by using Electron Spin Resonance (ESR), dynamics and structural changes in this region in the presence of a membrane model system. Overall, our ESR spectra show that the N-terminal indeed binds to membranes and that it experiences a somewhat high flexibility that could be related to the role of this region as a molecular lid controlling the entrance of the enzyme's active site and thus allowing the enzyme to give access to quinones that are dispersed in the membrane and that are necessary for the catalysis.

  17. Lactococcus lactis Dihydroorotate Dehydrogenase A Mutants Reveal Important Facets of the Enzymatic Function

    DEFF Research Database (Denmark)

    Nørager, Sofie Charlotte; Arent, S; Björnberg, Olof;

    2003-01-01

    and 1B, and class 2. This division corresponds to differences in cellular location and the nature of the electron acceptor. Herein we report a study of Lactococcus lactis DHODA, a representative of the class 1A enzymes. Based on the DHODA structure we selected seven residues that are highly conserved...

  18. Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model

    Energy Technology Data Exchange (ETDEWEB)

    Booker, Michael L.; Bastos, Cecilia M.; Kramer, Martin L.; Barker, Jr., Robert H.; Skerlj, Renato; Sidhu, Amar Bir; Deng, Xiaoyi; Celatka, Cassandra; Cortese, Joseph F.; Guerrero Bravo, Jose E.; Crespo Llado, Keila N.; Serrano, Adelfa E.; Angulo-Barturen, Iñigo; Jiménez-Díaz, María Belén; Viera, Sara; Garuti, Helen; Wittlin, Sergio; Papastogiannidis, Petros; Lin, Jing-wen; Janse, Chris J.; Khan, Shahid M.; Duraisingh, Manoj; Coleman, Bradley; Goldsmith, Elizabeth J.; Phillips, Margaret A.; Munoz, Benito; Wirth, Dyann F.; Klinger, Jeffrey D.; Wiegand, Roger; Sybertz, Edmund (Leiden-MC); (Puerto Rico); (STPHI); (Harvard); (GSK); (Genzyme); (UTSMC)

    2010-11-22

    Plasmodium falciparum, the causative agent of the most deadly form of human malaria, is unable to salvage pyrimidines and must rely on de novo biosynthesis for survival. Dihydroorotate dehydrogenase (DHODH) catalyzes the rate-limiting step in the pyrimidine biosynthetic pathway and represents a potential target for anti-malarial therapy. A high throughput screen and subsequent medicinal chemistry program identified a series of N-alkyl-5-(1H-benzimidazol-1-yl)thiophene-2-carboxamides with low nanomolar in vitro potency against DHODH from P. falciparum, P. vivax, and P. berghei. The compounds were selective for the parasite enzymes over human DHODH, and x-ray structural data on the analog Genz-667348, demonstrated that species selectivity could be attributed to amino acid differences in the inhibitor-binding site. Compounds from this series demonstrated in vitro potency against the 3D7 and Dd2 strains of P. falciparum, good tolerability and oral exposure in the mouse, and ED{sub 50} values in the 4-day murine P. berghei efficacy model of 13-21 mg/kg/day with oral twice-daily dosing. In particular, treatment with Genz-667348 at 100 mg/kg/day resulted in sterile cure. Two recent analogs of Genz-667348 are currently undergoing pilot toxicity testing to determine suitability as clinical development candidates.

  19. A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria.

    Science.gov (United States)

    Phillips, Margaret A; Lotharius, Julie; Marsh, Kennan; White, John; Dayan, Anthony; White, Karen L; Njoroge, Jacqueline W; El Mazouni, Farah; Lao, Yanbin; Kokkonda, Sreekanth; Tomchick, Diana R; Deng, Xiaoyi; Laird, Trevor; Bhatia, Sangeeta N; March, Sandra; Ng, Caroline L; Fidock, David A; Wittlin, Sergio; Lafuente-Monasterio, Maria; Benito, Francisco Javier Gamo; Alonso, Laura Maria Sanz; Martinez, Maria Santos; Jimenez-Diaz, Maria Belen; Bazaga, Santiago Ferrer; Angulo-Barturen, Iñigo; Haselden, John N; Louttit, James; Cui, Yi; Sridhar, Arun; Zeeman, Anna-Marie; Kocken, Clemens; Sauerwein, Robert; Dechering, Koen; Avery, Vicky M; Duffy, Sandra; Delves, Michael; Sinden, Robert; Ruecker, Andrea; Wickham, Kristina S; Rochford, Rosemary; Gahagen, Janet; Iyer, Lalitha; Riccio, Ed; Mirsalis, Jon; Bathhurst, Ian; Rueckle, Thomas; Ding, Xavier; Campo, Brice; Leroy, Didier; Rogers, M John; Rathod, Pradipsinh K; Burrows, Jeremy N; Charman, Susan A

    2015-07-15

    Malaria is one of the most significant causes of childhood mortality, but disease control efforts are threatened by resistance of the Plasmodium parasite to current therapies. Continued progress in combating malaria requires development of new, easy to administer drug combinations with broad-ranging activity against all manifestations of the disease. DSM265, a triazolopyrimidine-based inhibitor of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase (DHODH), is the first DHODH inhibitor to reach clinical development for treatment of malaria. We describe studies profiling the biological activity, pharmacological and pharmacokinetic properties, and safety of DSM265, which supported its advancement to human trials. DSM265 is highly selective toward DHODH of the malaria parasite Plasmodium, efficacious against both blood and liver stages of P. falciparum, and active against drug-resistant parasite isolates. Favorable pharmacokinetic properties of DSM265 are predicted to provide therapeutic concentrations for more than 8 days after a single oral dose in the range of 200 to 400 mg. DSM265 was well tolerated in repeat-dose and cardiovascular safety studies in mice and dogs, was not mutagenic, and was inactive against panels of human enzymes/receptors. The excellent safety profile, blood- and liver-stage activity, and predicted long half-life in humans position DSM265 as a new potential drug combination partner for either single-dose treatment or once-weekly chemoprevention. DSM265 has advantages over current treatment options that are dosed daily or are inactive against the parasite liver stage. PMID:26180101

  20. Structure and Function of Cross-class Complexes of G Protein-coupled Secretin and Angiotensin 1a Receptors.

    Science.gov (United States)

    Harikumar, Kaleeckal G; Augustine, Mary Lou; Lee, Leo T O; Chow, Billy K C; Miller, Laurence J

    2016-08-12

    Complexes of secretin (SecR) and angiotensin 1a (Atr1a) receptors have been proposed to be functionally important in osmoregulation, providing an explanation for overlapping and interdependent functions of hormones that bind and activate different classes of GPCRs. However, the nature of these cross-class complexes has not been well characterized and their signaling properties have not been systematically explored. We now use competitive inhibition of receptor bioluminescence resonance energy transfer and bimolecular fluorescence complementation to establish the dominant functionally important state as a symmetrical homodimeric form of SecR decorated by monomeric Atr1a, interacting through lipid-exposed faces of Atr1a TM1 and TM4. Conditions increasing prevalence of this complex exhibited negative allosteric modulatory impact on secretin-stimulated cAMP responses at SecR. In contrast, activating Atr1a with full agonist in such a complex exhibited a positive allosteric modulatory impact on the same signaling event. This modulation was functionally biased, with secretin-stimulated calcium responses unaffected, whereas angiotensin-stimulated calcium responses through the complex were reduced or absent. Further supporting this interpretation, Atr1a with mutations of lipid-exposed faces of TM1 and TM4 that did not affect its ability to bind or signal, could be expressed in the same cell as SecR, yet not exhibit either the negative or positive allosteric impact on cAMP observed with the inactive or activated states of wild type Atr1a on function, and not interfere with angiotensin-stimulated calcium responses like complexes with Atr1a. This may provide a more selective means of exploring the physiologic functional impact of this cross-class receptor complex without interfering with the function of either component receptor. PMID:27330080

  1. Characterization and expression pattern ofpouII1,a novel class Ⅱ POU gene in zebrafish

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    POU domain transcription factors that share a conserved DNA-binding domain, POU domain, are important regulators for the development of embryos in various animal species. A novel zebrafish POU domain gene, pouII1has been cloned. The pouII1 cDNA is 2080 kb in length and encodes a putative polypeptide of 596 amino acids. It is placed into class Ⅱ POU family since it shares a high degree of homology with the known members of this family.Northern hybridization identifies a major transcript of approximately 2.1 kb that was present in embryos at the single-cell stage throughout 24 h postfertilizafion. The whole mountin situ hybridization shows thatpouII1 transcripts are present in the single-cell embryos, strongly suggesting that these transcripts are of maternal origin. During early development of the embryos, pouII1 mRNA was ubiquitously distributed in all cells and tissues. The transcripts are gradually limited to brains and become completely undetectable by day 3. To our knowledge, pouII1 is the first class Ⅱ POU gene identified in zebrafish.``

  2. In Vitro Resistance Selections for Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors Give Mutants with Multiple Point Mutations in the Drug-binding Site and Altered Growth*

    OpenAIRE

    Ross, Leila S.; Gamo, Francisco Javier; Lafuente-Monasterio, Maria José; Singh, Onkar M. P.; Rowland, Paul; Wiegand, Roger C.; Wirth, Dyann F

    2014-01-01

    Malaria is a preventable and treatable disease; yet half of the world's population lives at risk of infection, and an estimated 660,000 people die of malaria-related causes every year. Rising drug resistance threatens to make malaria untreatable, necessitating both the discovery of new antimalarial agents and the development of strategies to identify and suppress the emergence and spread of drug resistance. We focused on in-development dihydroorotate dehydrogenase (DHODH) inhibitors. Characte...

  3. SCO-1, a Novel Plasmid-Mediated Class A β-Lactamase with Carbenicillinase Characteristics from Escherichia coli▿

    Science.gov (United States)

    Papagiannitsis, C. C.; Loli, A.; Tzouvelekis, L. S.; Tzelepi, E.; Arlet, G.; Miriagou, V.

    2007-01-01

    A novel class A β-lactamase (SCO-1) encoded by an 80-kb self-transferable plasmid from Escherichia coli is described. The interaction of SCO-1 with β-lactams was similar to that of the CARB-type enzymes. Also, SCO-1 exhibited a 51% amino acid sequence identity with the RTG subgroup of chromosomal carbenicillinases (RTG-1, CARB-5, and CARB-8). PMID:17353248

  4. SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli.

    Science.gov (United States)

    Papagiannitsis, C C; Loli, A; Tzouvelekis, L S; Tzelepi, E; Arlet, G; Miriagou, V

    2007-06-01

    A novel class A beta-lactamase (SCO-1) encoded by an 80-kb self-transferable plasmid from Escherichia coli is described. The interaction of SCO-1 with beta-lactams was similar to that of the CARB-type enzymes. Also, SCO-1 exhibited a 51% amino acid sequence identity with the RTG subgroup of chromosomal carbenicillinases (RTG-1, CARB-5, and CARB-8). PMID:17353248

  5. SCO-1, a Novel Plasmid-Mediated Class A β-Lactamase with Carbenicillinase Characteristics from Escherichia coli▿

    OpenAIRE

    Papagiannitsis, C. C.; Loli, A; Tzouvelekis, L. S.; Tzelepi, E.; Arlet, G; Miriagou, V.

    2007-01-01

    A novel class A β-lactamase (SCO-1) encoded by an 80-kb self-transferable plasmid from Escherichia coli is described. The interaction of SCO-1 with β-lactams was similar to that of the CARB-type enzymes. Also, SCO-1 exhibited a 51% amino acid sequence identity with the RTG subgroup of chromosomal carbenicillinases (RTG-1, CARB-5, and CARB-8).

  6. Characterization of SFO-1, a plasmid-mediated inducible class A beta-lactamase from Enterobacter cloacae.

    Science.gov (United States)

    Matsumoto, Y; Inoue, M

    1999-02-01

    Enterobacter cloacae 8009 produced an inducible class A beta-lactamase which hydrolyzed cefotaxime efficiently. It also hydrolyzed other beta-lactams except cephamycins and carbapenems. The activity was inhibited by clavulanic acid and imipenem. The bla gene was transferable to Escherichia coli by electroporation of plasmid DNA. The molecular mass of the beta-lactamase was 29 kDa and its pI was 7.3. All of these phenotypic characteristics of the enzyme except for inducible production resemble those of some extended-spectrum class A beta-lactamases like FEC-1. The gene encoding this beta-lactamase was cloned and sequenced. The deduced amino acid sequence of the beta-lactamase was homologous to the AmpA sequences of the Serratia fonticola chromosomal enzyme (96%), MEN-1 (78%), Klebsiella oxytoca chromosomal enzymes (77%), TOHO-1 (75%), and FEC-1 (72%). The conserved sequences of class A beta-lactamases, including the S-X(T)-X(S)-K motif, in the active site were all conserved in this enzyme. On the basis of the high degree of homology to the beta-lactamase of S. fonticola, the enzyme was named SFO-1. The ampR gene was located upstream of the ampA gene, and the AmpR sequence of SFO-1 had homology with the AmpR sequences of the chromosomal beta-lactamases from Citrobacter diversus (80%), Proteus vulgaris (68%), and Pseudomonas aeruginosa (60%). SFO-1 was also inducible in E. coli. However, a transformant harboring plasmid without intact ampR produced a small amount of beta-lactamase constitutively, suggesting that AmpR works as an activator of ampA of SFO-1. This is the first report from Japan describing an inducible plasmid-mediated class A beta-lactamase in gram-negative bacteria. PMID:9925524

  7. Genetic and biochemical characterization of FRI-1, a carbapenem-hydrolyzing class A β-Lactamase from Enterobacter cloacae

    OpenAIRE

    Dortet, Laurent; Poirel , Laurent; Abbas, Samia; Oueslati, Saoussen; Nordmann, Patrice

    2016-01-01

    An Enterobacter cloacae isolate was recovered from a rectal swab from a patient hospitalized in France with previous travel to Switzerland. It was resistant to penicillins, narrow- and broad-spectrum cephalosporins, aztreonam, and carbapenems but remained susceptible to expanded-spectrum cephalosporins. Whereas PCR-based identification of the most common carbapenemase genes failed, the biochemical Carba NP test II identified an Ambler class A carbapenemase. Cloning experiments followed ...

  8. Characterization of SFO-1, a Plasmid-Mediated Inducible Class A β-Lactamase from Enterobacter cloacae

    OpenAIRE

    Matsumoto, Yoshimi; Inoue, Matsuhisa

    1999-01-01

    Enterobacter cloacae 8009 produced an inducible class A β-lactamase which hydrolyzed cefotaxime efficiently. It also hydrolyzed other β-lactams except cephamycins and carbapenems. The activity was inhibited by clavulanic acid and imipenem. The bla gene was transferable to Escherichia coli by electroporation of plasmid DNA. The molecular mass of the β-lactamase was 29 kDa and its pI was 7.3. All of these phenotypic characteristics of the enzyme except for inducible production resemble those of...

  9. Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential

    Energy Technology Data Exchange (ETDEWEB)

    Coteron, Jose M.; Marco, Maria; Esquivias, Jorge; Deng, Xiaoyi; White, Karen L.; White, John; Koltun, Maria; El Mazouni, Farah; Kokkonda, Sreekanth; Katneni, Kasiram; Bhamidipati, Ravi; Shackleford, David M.; Angulo-Barturen, Inigo; Ferrer, Santiago B.; Jimenez-Diaz, Maria Belen; Gamo, Francisco-Javier; Goldsmith, Elizabeth J.; Charman, William N.; Bathurst, Ian; Floyd, David; Matthews, David; Burrows, Jeremy N.; Rathod, Pradipsinh K.; Charman, Susan A.; Phillips, Margaret A. (UWASH); (MMV, Switzerland); (GSK); (Monash); (UW); (UTSMC)

    2012-02-27

    Drug therapy is the mainstay of antimalarial therapy, yet current drugs are threatened by the development of resistance. In an effort to identify new potential antimalarials, we have undertaken a lead optimization program around our previously identified triazolopyrimidine-based series of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitors. The X-ray structure of PfDHODH was used to inform the medicinal chemistry program allowing the identification of a potent and selective inhibitor (DSM265) that acts through DHODH inhibition to kill both sensitive and drug resistant strains of the parasite. This compound has similar potency to chloroquine in the humanized SCID mouse P. falciparum model, can be synthesized by a simple route, and rodent pharmacokinetic studies demonstrated it has excellent oral bioavailability, a long half-life and low clearance. These studies have identified the first candidate in the triazolopyrimidine series to meet previously established progression criteria for efficacy and ADME properties, justifying further development of this compound toward clinical candidate status.

  10. Frequent lack of translation of antigen presentation-associated molecules MHC class I, CD1a and Beta(2)-microglobulin in Reed-Sternberg cells

    NARCIS (Netherlands)

    van den Berg, A.; Visser, L; Eberwine, J; Dadvand, L; Poppema, S

    2000-01-01

    Epstein-Barr virus (EBV) is present in Reed-Sternberg (RS) cells of a substantial proportion of Hodgkin's lymphoma cases. Most EBV-positive cases are also MHC class I-positive, whereas the majority of EBV-negative cases lack detectable levels of MHC class I expression. Application of the SAGE techni

  11. Anticancer properties of distinct antimalarial drug classes.

    Directory of Open Access Journals (Sweden)

    Rob Hooft van Huijsduijnen

    Full Text Available We have tested five distinct classes of established and experimental antimalarial drugs for their anticancer potential, using a panel of 91 human cancer lines. Three classes of drugs: artemisinins, synthetic peroxides and DHFR (dihydrofolate reductase inhibitors effected potent inhibition of proliferation with IC50s in the nM- low µM range, whereas a DHODH (dihydroorotate dehydrogenase and a putative kinase inhibitor displayed no activity. Furthermore, significant synergies were identified with erlotinib, imatinib, cisplatin, dasatinib and vincristine. Cluster analysis of the antimalarials based on their differential inhibition of the various cancer lines clearly segregated the synthetic peroxides OZ277 and OZ439 from the artemisinin cluster that included artesunate, dihydroartemisinin and artemisone, and from the DHFR inhibitors pyrimethamine and P218 (a parasite DHFR inhibitor, emphasizing their shared mode of action. In order to further understand the basis of the selectivity of these compounds against different cancers, microarray-based gene expression data for 85 of the used cell lines were generated. For each compound, distinct sets of genes were identified whose expression significantly correlated with compound sensitivity. Several of the antimalarials tested in this study have well-established and excellent safety profiles with a plasma exposure, when conservatively used in malaria, that is well above the IC50s that we identified in this study. Given their unique mode of action and potential for unique synergies with established anticancer drugs, our results provide a strong basis to further explore the potential application of these compounds in cancer in pre-clinical or and clinical settings.

  12. Characterization of VCC-1, a Novel Ambler Class A Carbapenemase from Vibrio cholerae Isolated from Imported Retail Shrimp Sold in Canada.

    Science.gov (United States)

    Mangat, Chand S; Boyd, David; Janecko, Nicol; Martz, Sarah-Lynn; Desruisseau, Andrea; Carpenter, Michael; Reid-Smith, Richard J; Mulvey, Michael R

    2016-03-01

    One of the core goals of the Canadian Integrated Program for Antimicrobial Resistance Surveillance (CIPARS) is to monitor major meat commodities for antimicrobial resistance. Targeted studies with methodologies based on core surveillance protocols are used to examine other foods, e.g., seafood, for antimicrobial resistance to detect resistances of concern to public health. Here we report the discovery of a novel Ambler class A carbapenemase that was identified in a nontoxigenic strain of Vibrio cholerae (N14-02106) isolated from shrimp that was sold for human consumption in Canada. V. cholerae N14-02106 was resistant to penicillins, carbapenems, and monobactam antibiotics; however, PCR did not detect common β-lactamases. Bioinformatic analysis of the whole-genome sequence of V. cholerae N14-02106 revealed on the large chromosome a novel carbapenemase (referred to here as VCC-1, for Vibrio cholerae carbapenemase 1) with sequence similarity to class A enzymes. Two copies of blaVCC-1 separated and flanked by ISVch9 (i.e., 3 copies of ISVch9) were found in an acquired 8.5-kb region inserted into a VrgG family protein gene. Cloned blaVCC-1 conferred a β-lactam resistance profile similar to that in V. cholerae N14-02106 when it was transformed into a susceptible laboratory strain of Escherichia coli. Purified VCC-1 was found to hydrolyze penicillins, 1st-generation cephalosporins, aztreonam, and carbapenems, whereas 2nd- and 3rd-generation cephalosporins were poor substrates. Using nitrocefin as a reporter substrate, VCC-1 was moderately inhibited by clavulanic acid and tazobactam but not EDTA. In this report, we present the discovery of a novel class A carbapenemase from the food supply. PMID:26824956

  13. Class size versus class composition

    DEFF Research Database (Denmark)

    Jones, Sam

    Raising schooling quality in low-income countries is a pressing challenge. Substantial research has considered the impact of cutting class sizes on skills acquisition. Considerably less attention has been given to the extent to which peer effects, which refer to class composition, also may affect...

  14. Word classes

    DEFF Research Database (Denmark)

    Rijkhoff, Jan

    2007-01-01

    This article provides an overview of recent literature and research on word classes, focusing in particular on typological approaches to word classification. The cross-linguistic classification of word class systems (or parts-of-speech systems) presented in this article is based on statements found...... in grammatical descriptions of some 50 languages, which together constitute a representative sample of the world’s languages (Hengeveld et al. 2004: 529). It appears that there are both quantitative and qualitative differences between word class systems of individual languages. Whereas some languages...... employ a parts-of-speech system that includes the categories Verb, Noun, Adjective and Adverb, other languages may use only a subset of these four lexical categories. Furthermore, quite a few languages have a major word class whose members cannot be classified in terms of the categories Verb – Noun...

  15. Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors: design, synthesis, and effects on behavior

    DEFF Research Database (Denmark)

    Butini, Stefania; Gemma, Sandra; Campiani, Giuseppe;

    2009-01-01

    Dopamine D(3) antagonism combined with serotonin 5-HT(1A) and 5-HT(2A) receptor occupancy may represent a novel paradigm for developing innovative antipsychotics. The unique pharmacological features of 5i are a high affinity for dopamine D(3), serotonin 5-HT(1A) and 5-HT(2A) receptors, together w...

  16. Class distinction

    Science.gov (United States)

    White, M. Catherine

    Typical 101 courses discourage many students from pursuing higher level science and math courses. Introductory classes in science and math serve largely as a filter, screening out all but the most promising students, and leaving the majority of college graduates—including most prospective teachers—with little understanding of how science works, according to a study conducted for the National Science Foundation. Because few teachers, particularly at the elementary level, experience any collegiate science teaching that stresses skills of inquiry and investigation, they simply never learn to use those methods in their teaching, the report states.

  17. Expression of organic anion-transporting polypeptides 1B3, 1B1, and 1A2 in human pancreatic cancer reveals a new class of potential therapeutic targets

    Directory of Open Access Journals (Sweden)

    Kounnis V

    2011-04-01

    Full Text Available Valentinos Kounnis1, Elli Ioachim2, Martin Svoboda3, Andreas Tzakos4, Ioannis Sainis1, Theresia Thalhammer3, Georg Steiner5, Evangelos Briasoulis11Cancer Biobank Center of the University of Ioannina, Greece; 2Pathology Department of Hatzikosta General Hospital, Ioannina Greece; 3Department of Pathophysiology and Allergy Research, Medical University of Vienna, Austria; 4Department of Chemistry, University of Ioannina, Greece; 5TissueGnostics GmbH, Vienna, AustriaBackground: Organic anion-transporting polypeptides (OATPs are influx transporters that mediate intracellular uptake of selective endogenous and xenobiotic compounds. Identification of new molecular targets and discovery of novel targeted therapies is top priority for pancreatic cancer, which lacks any effective therapy.Materials and methods: We studied expression of OATP 1A2, 1B1, and 1B3 in pancreatic cancer tissue and in cell lines. Formalin-fixed paraffin-embedded biopsy material of 12 human pancreatic cancers was immunohistochemically assessed for protein expression of the three studied influx transporters. Immunohistochemistry was evaluated by experienced pathologists and quantified by use of an automated image analysis system. BxPC-3 and MIA PaCa-2 pancreatic cancer cell lines were used to quantify transcripts of OATP 1B1 and 1B3.Results: OATP 1A2, 1B1, and 1B3 proteins were found ubiquitously expressed in all studied cases. Quantification performed by HistoQuest system revealed that mean intensity was 53 for 1A2, 45 for 1B1, and 167 for OATP 1B1/1B3 on a range scale 0–250 units. At mRNA level, 1B1 and 1B3 were overexpressed in both studied cancer cell lines but not in normal pancreatic tissue.Conclusion: OATPs 1A2, 1B1, and 1B3 are highly expressed in pancreatic adenocarcinoma. We suggest that expression of these transporters in pancreatic cancer justify research efforts towards discovery of novel therapeutics targeting OATPs.Keywords: organic anion-transporting polypeptides

  18. Interferon Beta-1a Intramuscular Injection

    Science.gov (United States)

    Interferon beta-1a intramuscular injection is used to reduce the number of episodes of symptoms and slow ... and problems with vision, speech, and bladder control). Interferon beta-1a is in a class of medications ...

  19. Interferon Beta-1a Subcutaneous Injection

    Science.gov (United States)

    Interferon beta-1a subcutaneous injection is used to reduce episodes of symptoms and slow the development of ... and problems with vision, speech, and bladder control). Interferon beta-1a is in a class of medications ...

  20. Class Vectors: Embedding representation of Document Classes

    OpenAIRE

    Sachan, Devendra Singh; Kumar, Shailesh

    2015-01-01

    Distributed representations of words and paragraphs as semantic embeddings in high dimensional data are used across a number of Natural Language Understanding tasks such as retrieval, translation, and classification. In this work, we propose "Class Vectors" - a framework for learning a vector per class in the same embedding space as the word and paragraph embeddings. Similarity between these class vectors and word vectors are used as features to classify a document to a class. In experiment o...

  1. Teachers in Class

    Science.gov (United States)

    Van Galen, Jane

    2008-01-01

    In this article, I argue for a closer read of the daily "class work" of teachers, as posited by Reay, 1998. In developing exploratory class portraits of four teachers who occupy distinctive social positions (two from working-class homes now teaching upper-middle-class children and two from upper-middle-class homes now teaching poor children), I…

  2. Does Class Size Matter?

    Science.gov (United States)

    Ehrenberg, Ronald G.; Brewer, Dominic J.; Gamoran, Adam; Willms, J. Douglas

    2001-01-01

    Reports on the significance of class size to student learning. Includes an overview of class size in various countries, the importance of teacher adaptability, and the Asian paradox of large classes allied to high test scores. (MM)

  3. Loosely coupled class families

    DEFF Research Database (Denmark)

    Ernst, Erik

    2001-01-01

    Families of mutually dependent classes that may be accessed polymor- phically provide an advanced tool for separation of concerns, in that it enables client code to use a group of instances of related classes safely without depending on the exact classes involved. However, class families which are...... expressed using virtual classes seem to be very tightly coupled internally. While clients have achieved the freedom to dynamically use one or the other family, it seems that any given family contains a xed set of classes and we will need to create an entire family of its own just in order to replace one of...... the members with another class. This paper shows how to express class families in such a manner that the classes in these families can be used in many dierent combinations, still enabling family polymorphism and ensuring type safety....

  4. A Virtual Class Calculus

    DEFF Research Database (Denmark)

    Ernst, Erik; Ostermann, Klaus; Cook, William Randall

    2006-01-01

    , statically typed model for virtual classes has been a long-standing open question. This paper presents a virtual class calculus, vc, that captures the essence of virtual classes in these full-fledged programming languages. The key contributions of the paper are a formalization of the dynamic and static...

  5. Semantic Analysis of Virtual Classes and Nested Classes

    DEFF Research Database (Denmark)

    Madsen, Ole Lehrmann

    1999-01-01

    Virtual classes and nested classes are distinguishing features of BETA. Nested classes originated from Simula, but until recently they have not been part of main stream object- oriented languages. C++ has a restricted form of nested classes and they were included in Java 1.1. Virtual classes is the...... classes and parameterized classes have been made. Although virtual classes and nested classes have been used in BETA for more than a decade, their implementation has not been published. The purpose of this paper is to contribute to the understanding of virtual classes and nested classes by presenting the...

  6. Class network routing

    Science.gov (United States)

    Bhanot, Gyan; Blumrich, Matthias A.; Chen, Dong; Coteus, Paul W.; Gara, Alan G.; Giampapa, Mark E.; Heidelberger, Philip; Steinmacher-Burow, Burkhard D.; Takken, Todd E.; Vranas, Pavlos M.

    2009-09-08

    Class network routing is implemented in a network such as a computer network comprising a plurality of parallel compute processors at nodes thereof. Class network routing allows a compute processor to broadcast a message to a range (one or more) of other compute processors in the computer network, such as processors in a column or a row. Normally this type of operation requires a separate message to be sent to each processor. With class network routing pursuant to the invention, a single message is sufficient, which generally reduces the total number of messages in the network as well as the latency to do a broadcast. Class network routing is also applied to dense matrix inversion algorithms on distributed memory parallel supercomputers with hardware class function (multicast) capability. This is achieved by exploiting the fact that the communication patterns of dense matrix inversion can be served by hardware class functions, which results in faster execution times.

  7. Fostering a Middle Class

    Institute of Scientific and Technical Information of China (English)

    YAO BIN

    2011-01-01

    Though there is no official definition of "middle class" in China,the tag has become one few Chinese people believe they deserve anyway.In early August,the Chinese Academy of Social Sciences released a report on China's urban development,saying China had a middle-class population of 230 million in 2009,or 37 percent of its urban residents.It also forecast half of city dwellers in China would be part of the middle class by 2023.

  8. New laser classes

    International Nuclear Information System (INIS)

    By an up-dated international standard (IEC 60825-1 + Amendment 2) on laser safety some new laser classes are introduced. The new set of laser classes consists of 1, 1M, 2, 2M, 3R, 3B, and 4. This is a result of intense discussions in the committee and was laid down in 2000, slightly adjusted 2001. The previous classes 1, 2, 3A, 3B, and 4, established since more than 25 years, are partly abandoned. This paper compares the new classes to the old ones. (orig.)

  9. Class, Culture and Politics

    DEFF Research Database (Denmark)

    Harrits, Gitte Sommer

    2013-01-01

    , discussions within political sociology have not yet utilized the merits of a multidimensional conception of class. In light of this, the article suggests a comprehensive Bourdieusian framework for class analysis, integrating culture as both a structural phenomenon co-constitutive of class and as symbolic...... practice. Further, the article explores this theoretical framework in a multiple correspondence analysis of a Danish survey, demonstrating how class and political practices are indeed homologous. However, the analysis also points at several elements of field autonomy, and the concluding discussion...

  10. Teaching Large Evening Classes

    Science.gov (United States)

    Wambuguh, Oscar

    2008-01-01

    High enrollments, conflicting student work schedules, and the sheer convenience of once-a-week classes are pushing many colleges to schedule evening courses. Held from 6 to 9 pm or 7 to 10 pm, these classes are typically packed, sometimes with more than 150 students in a large lecture theater. How can faculty effectively teach, control, or even…

  11. Class in disguise

    DEFF Research Database (Denmark)

    Faber, Stine Thidemann; Prieur, Annick

    This paper asks how class can have importance in one of the worlds’ most equal societies: Denmark. The answer is that class here appears in disguised forms. The field under study is a city, Aalborg, in the midst of transition from a stronghold of industrialism to a post industrial economy...

  12. Teaching Social Class

    Science.gov (United States)

    Tablante, Courtney B.; Fiske, Susan T.

    2015-01-01

    Discussing socioeconomic status in college classes can be challenging. Both teachers and students feel uncomfortable, yet social class matters more than ever. This is especially true, given increased income inequality in the United States and indications that higher education does not reduce this inequality as much as many people hope. Resources…

  13. DEFINING THE MIDDLE CLASS

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Classifying the middle class remains controversial despite its alleged growth China’s cities housed more than 230 million middle-class residents in 2009 or 37 percent of the urban population,according to the 2011 Blue Book of Cities in China released on August 3.

  14. Social Class Dialogues and the Fostering of Class Consciousness

    Science.gov (United States)

    Madden, Meredith

    2015-01-01

    How do critical pedagogies promote undergraduate students' awareness of social class, social class identity, and social class inequalities in education? How do undergraduate students experience class consciousness-raising in the intergroup dialogue classroom? This qualitative study explores undergraduate students' class consciousness-raising in an…

  15. Teaching Heterogeneous Classes.

    Science.gov (United States)

    Millrood, Radislav

    2002-01-01

    Discusses an approach to teaching heterogeneous English-as-a-Second/Foreign-Language classes. Draws on classroom research data to describe the features of a success-building lesson context. (Author/VWL)

  16. IELP Class Observation

    Institute of Scientific and Technical Information of China (English)

    陈了了

    2010-01-01

    @@ As an exchange student majoring in English, I am curious about how English is taught to international students here in America. Therefore, I observed an IELP (Intensive English Learning Program) class in Central Connecticut State University where I study.

  17. PSYCH 515 Complete Class

    OpenAIRE

    admin

    2015-01-01

      PSYCH 515 Advanced Abnormal Psychology To purchase this material click on below link http://www.assignmentcloud.com/PSYCH-515/PSYCH-515-Complete-Class-Guide For more details www.assignmentcloud.com

  18. Raradox of class description

    Institute of Scientific and Technical Information of China (English)

    吕光

    2004-01-01

    We have a more active class atmophere, but more passive self-study situations. We are too talktive when we should bury ourselves in books, but too less efficient when we spend too much time. We complain teachers

  19. Nordic Walking Classes

    CERN Multimedia

    Fitness Club

    2015-01-01

    Four classes of one hour each are held on Tuesdays. RDV barracks parking at Entrance A, 10 minutes before class time. Spring Course 2015: 05.05/12.05/19.05/26.05 Prices 40 CHF per session + 10 CHF club membership 5 CHF/hour pole rental Check out our schedule and enroll at: https://espace.cern.ch/club-fitness/Lists/Nordic%20Walking/NewForm.aspx? Hope to see you among us! fitness.club@cern.ch

  20. Embodying class and gender

    OpenAIRE

    Geers, Alexie

    2015-01-01

    In March 1937, when the first issue of Marie-Claire was published, the images of the female body it presented to its female readers from working-class backgrounds contrasted sharply with those featured in previous magazines. The female bodies are dressed and groomed to seduce and replace the hieratic bodies that presented fashions synonymous with membership in the upper classes. The present essay examines this shift and shows that the visual repertoire employed is borrowed from that of the fe...

  1. Generalized Fourier transforms classes

    DEFF Research Database (Denmark)

    Berntsen, Svend; Møller, Steen

    2002-01-01

    The Fourier class of integral transforms with kernels $B(\\omega r)$ has by definition inverse transforms with kernel $B(-\\omega r)$. The space of such transforms is explicitly constructed. A slightly more general class of generalized Fourier transforms are introduced. From the general theory foll...... follows that integral transform with kernels which are products of a Bessel and a Hankel function or which is of a certain general hypergeometric type have inverse transforms of the same structure....

  2. theories of class

    Science.gov (United States)

    Gaiotto, Davide; Razamat, Shlomo S.

    2015-07-01

    We construct classes of superconformal theories elements of which are labeled by punctured Riemann surfaces. Degenerations of the surfaces correspond, in some cases, to weak coupling limits. Different classes are labeled by two integers ( N, k). The k = 1 case coincides with A N - 1 theories of class and simple examples of theories with k > 1 are orbifolds of some of the A N - 1 class theories. For the space of theories to be complete in an appropriate sense we find it necessary to conjecture existence of new strongly coupled SCFTs. These SCFTs when coupled to additional matter can be related by dualities to gauge theories. We discuss in detail the A 1 case with k = 2 using the supersymmetric index as our analysis tool. The index of theories in classes with k > 1 can be constructed using eigenfunctions of elliptic quantum mechanical models generalizing the Ruijsenaars-Schneider integrable model. When the elliptic curve of the model degenerates these eigenfunctions become polynomials with coefficients being algebraic expressions in fugacities, generalizing the Macdonald polynomials with rational coefficients appearing when k = 1.

  3. Does class attendance still matter?

    OpenAIRE

    Abel Nyamapfene

    2010-01-01

    This paper presents a study on the impact of class attendance on academic performance in a second year Electronics Engineering course module with online notes and no mandatory class attendance policy. The study shows that class attendance is highly correlated to academic performance, despite the availability of online class notes. In addition, there is significant correlation between class attendance and non-class contact with the lecturer and between student performance in the first year of ...

  4. Translation in ESL Classes

    Directory of Open Access Journals (Sweden)

    Nagy Imola Katalin

    2015-12-01

    Full Text Available The problem of translation in foreign language classes cannot be dealt with unless we attempt to make an overview of what translation meant for language teaching in different periods of language pedagogy. From the translation-oriented grammar-translation method through the complete ban on translation and mother tongue during the times of the audio-lingual approaches, we have come today to reconsider the role and status of translation in ESL classes. This article attempts to advocate for translation as a useful ESL class activity, which can completely fulfil the requirements of communicativeness. We also attempt to identify some activities and games, which rely on translation in some books published in the 1990s and the 2000s.

  5. BIO 315 Complete Class

    OpenAIRE

    admn

    2015-01-01

    BIO 315 Complete Class Check this A+ tutorial guideline at   http://www.assignmentcloud.com/BIO-315/BIO-315-Complete-Class BIO 315 Week 1 DQ 1 BIO 315 Week 1 DQ 2 BIO 315 Week 1 Individual Assignment Beren Robinson Field Study Paper BIO 315 Week 2 DQ 1 BIO 315 Week 2 DQ 2 BIO 315 Week 2 DQ 3 BIO 315 Week 2 Individual Assignment Environment Resources and Competition BIO 315 Week 2 Week Two Learning Team Exercises BIO 315 Week 3 DQ 1 BIO ...

  6. Class actions in Portugal

    OpenAIRE

    Raimundo, Maria Carlos Miranda

    2013-01-01

    Even eighteen years after the implementation of Law 83/95, of August 31, about the rights of participation in class action litigation in Portugal, there is no sufficient evidence of its applicability. Contrarily to what is observed in other countries as the United States and Brazil it seems that in Portugal, there is no interest of the several parties that would be involved in a class action litigation to obtain information or inform other parties relatively to the main procedures on it and t...

  7. An "expanded" class perspective

    DEFF Research Database (Denmark)

    Steur, Luisa Johanna

    2014-01-01

    Adivasis against their age-old colonization or the work of ‘external’ agitators. Capitalist restructuring and ‘globalization’ was generally seen as simply the latest chapter in the suffering of these Adivasis. Little focused attention was paid to the recent class trajectory of their lives under changing...... analysis, as elaborated in Marxian anthropology, this article provides an alternative to the liberal-culturalist explanation of indigenism in Kerala, arguing instead that contemporary class processes—as experienced close to the skin by the people who decided to participate in the Muthanga struggle...

  8. Talking Class in Tehroon

    DEFF Research Database (Denmark)

    Elling, Rasmus Christian; Rezakhani, Khodadad

    2016-01-01

    Persian, like any other language, is laced with references to class, both blatant and subtle. With idioms and metaphors, Iranians can identify and situate others, and thus themselves, within hierarchies of social status and privilege, both real and imagined. Some class-related terms can be traced...... back to medieval times, whereas others are of modern vintage, the linguistic legacy of television shows, pop songs, social media memes or street vernacular. Every day, it seems, an infectious set of phrases appears that make yesterday’s seem embarrassingly antiquated....

  9. Residues of Chern classes

    OpenAIRE

    Suwa, Tatsuo; 諏訪, 立雄

    2003-01-01

    If we have a finite number of sections of a complex vector bundle E over a manifold M, certain Chern classes of E are localized at the singular set S, i.e., the set of points where the sections fail to be linearly independent. When S is compact, the localizations define the residues at each connected component of S by the Alexander duality. If M itself is compact, the sum of the residues is equal to the Poincaré dual of the corresponding Chern class. This type of theory is also developed for ...

  10. Residues of Chern classes

    OpenAIRE

    Suwa, Tatsuo

    2003-01-01

    If we have a finite number of sections of a complex vector bundle $E$ over a manifold $M$ , certain Chern classes of $E$ are localized at the singular set $S$ , i.e., the set of points where the sections fail to be linearly independent. When $S$ is compact, the localizations define the residues at each connected component of $S$ by the Alexander duality. If $M$ itself is compact, the sum of the residues is equal to the Poincaré dual of the corresponding Chern class. This type of theory is als...

  11. Teaching Very Large Classes

    Science.gov (United States)

    DeRogatis, Amy; Honerkamp, Kenneth; McDaniel, Justin; Medine, Carolyn; Nyitray, Vivian-Lee; Pearson, Thomas

    2014-01-01

    The editor of "Teaching Theology and Religion" facilitated this reflective conversation with five teachers who have extensive experience and success teaching extremely large classes (150 students or more). In the course of the conversation these professors exchange and analyze the effectiveness of several active learning strategies they…

  12. Reference class forecasting

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    Underbudgettering og budgetoverskridelser forekommer i et flertal af større bygge- og anlægsprojekter. Problemet skyldes optimisme og/eller strategisk misinformation i budgetteringsprocessen. Reference class forecasting (RCF) er en prognosemetode, som er udviklet for at reducere eller eliminere...

  13. Fostering a Middle Class

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Though there is no official definition of "middle class" in China, the tag has become one few Chinese people believe they deserve anyway.In early August, the Chinese Academy of Social Sciences released a report on China’s urban development,

  14. Second class weak currents

    International Nuclear Information System (INIS)

    The definition and general properties of weak second class currents are recalled and various detection possibilities briefly reviewed. It is shown that the existing data on nuclear beta decay can be consistently analysed in terms of a phenomenological model. Their implication on the fundamental structure of weak interactions is discussed

  15. Class Actions in Denmark

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2009-01-01

    The article deals with the relatively new Danish Act on Class Action (Danish: gruppesøgsmål) which was suggested by The Permanent Council on Civil procedure (Retsplejerådet) of which the article's author is a member. The operability of the new provisions is illustrated through some wellknown Danish...

  16. Adeus à classe trabalhadora?

    Directory of Open Access Journals (Sweden)

    Geoff Eley

    2013-12-01

    Full Text Available No início da década de 1980, a política centrada em classes da tradição socialista estava em crise, e comentadores importantes adotaram tons apocalípticos. No final da década, a esquerda permanecia profundamente dividida entre os advogados da mudança e os defensores da fé. Em meados dos anos 1990, os primeiros tinham, de modo geral, ganhado a batalha. O artigo busca apresentar essa mudança contemporânea não como a 'morte da classe', mas como o desa­parecimento de um tipo particular de ­sociedade de classes, marcado pelo ­processo de formação da classe trabalhadora entre os anos 1880 e 1940 e pelo alinhamento político daí resultante, atingindo seu apogeu na construção social-democrata do acordo do pós-guerra. Quando mudanças de longo prazo na economia se combinaram com o ataque ao keynesianismo na política de recessão a partir de meados da década de 1970, a unidade da classe trabalhadora deixou de estar disponível da forma antiga e bastante utilizada, como o terreno natural da política de esquerda. Enquanto uma coletividade dominante da classe trabalhadora entrou em declínio, outra se corporificou de modo lento e desigual para tomar o lugar daquela. Mas a unidade operacional dessa nova agregação da classe trabalhadora ainda está, em grande parte, em formação. Para recuperar a eficácia política da tradição socialista, alguma nova visão de agência política coletiva será necessária, uma visão imaginativamente ajustada às condições emergentes da produção e acumulação capitalista no início do século XXI.

  17. Flexible Word Classes

    DEFF Research Database (Denmark)

    van Lier, Eva; Rijkhoff, Jan

    2013-01-01

    • First major publication on the phenomenon • Offers cross-linguistic, descriptive, and diverse theoretical approaches • Includes analysis of data from different language families and from lesser studied languages This book is the first major cross-linguistic study of 'flexible words', i.e. words...... that cannot be classified in terms of the traditional lexical categories Verb, Noun, Adjective or Adverb. Flexible words can - without special morphosyntactic marking - serve in functions for which other languages must employ members of two or more of the four traditional, 'specialised' word classes....... Thus, flexible words are underspecified for communicative functions like 'predicating' (verbal function), 'referring' (nominal function) or 'modifying' (a function typically associated with adjectives and e.g. manner adverbs). Even though linguists have been aware of flexible world classes for more...

  18. Class Action and Class Settlement in a European Perspective

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2013-01-01

    The article analyses the options for introducing common European rules on class action lawsuits with an opt-out-model in individual cases. An analysis is made of how the risks of misuse of class actions can be prevented. The article considers the Dutch rules on class settlements (the WCAM procedure...

  19. GBM 489 Complete Class

    OpenAIRE

    admn

    2015-01-01

    GBM 489 Complete Class Check this A+ tutorial guideline at   http://www.assignmentcloud.com/GBM-489/GBM-489-Strategic-Topics-in-Global-Business-Management GBM 489 Strategic Topics in Global Business Management GBM 489 Week 1 DQ 1 GBM 489 Week 1 DQ 2 GBM 489 Week 1 DQ 3 GBM 489 Week 1 Individual Global Trends Paper GBM 489 Week 2 DQ 1 GBM 489 Week 2 DQ 2 GBM 489 Week 2 DQ 3 GBM 489 Week 2 Individual Business Plan Article Analysis GBM 489...

  20. The Class of '34

    OpenAIRE

    Cairney, Richard

    1995-01-01

    The Great Depression raged, governments were beleaguered, the unemployment rate stood at 30%, scurvy stalked the poor and no one was immune to contagious diseases such as scarlet fever, polio and measles when the University of Alberta School of Medicine's Class of '34 graduated. For four alumni who recently gathered in Edmonton—Drs. Morley Hodgson, Melvin Gaudin, John McLurg and Edmund Cairns—their 60th-anniversary reunion was a time to recall the changes they have witnessed in medicine, incl...

  1. Mining Java Class Naming Conventions

    OpenAIRE

    Butler, Simon; Wermelinger, Michel; Yu, Yijun; Sharp, Helen

    2011-01-01

    Class names represent the concepts implemented in object-oriented source code and are key elements in program comprehension and, thus, software maintenance. Programming conventions often state that class names should be noun-phrases, but there is little further guidance for developers on the composition of class names. Other researchers have observed that the majority of Java class identifier names are composed of one or more nouns preceded, optionally, by one or more adjectives. However, no ...

  2. URBAN AND REGIONAL CREATIVE CLASS THEORIES

    OpenAIRE

    Tremblay, Remy; CHICOINE, Huges

    2011-01-01

    The creative class theory suggests that society is composed of three social classes: the creative class, the service class, the working class, a different view or classification of the workforce. The boundaries separating the creative class from the upper ruling class and the lower working class rest on occupational premises. This paper examines the construction and tools of the creative class, its human composition as a social class, attending discourses, as well as the shifting foundations ...

  3. Teachers, Social Class and Underachievement

    Science.gov (United States)

    Dunne, Mairead; Gazeley, Louise

    2008-01-01

    Addressing the "the social class attainment gap" in education has become a government priority in England. Despite multiple initiatives, however, little has effectively addressed the underachievement of working-class pupils within the classroom. In order to develop clearer understandings of working-class underachievement at this level, this small…

  4. Understanding Class in Contemporary Societies

    DEFF Research Database (Denmark)

    Harrits, Gitte Sommer

    In this paper, I argue that claims about the death of class and the coming of the classless society are premature. Such claims are seldom genuinely empirical, and the theoretical argument often refers to a simple and therefore easily dismissible concept of class. By rejecting the concept of class...... altogether, sociological theory runs the risk of loosing the capacity for analysing stratification and vertical differentiation of power and freedom, which in late modernity seem to be a of continuing importance. Hence, I argue that although class analysis faces a number of serious challenges, it is possible...... to reinvent class analysis. The sociology of Pierre Bourdieu in many ways introduces an appropriate paradigm, and the paper therefore critically discusses Bourdieu's concept of class. Since the "Bourdieuan" class concept is primarily epistemological, i.e. a research strategy more than a theory...

  5. Pseudo Class III malocclusion.

    Science.gov (United States)

    Al-Hummayani, Fadia M

    2016-04-01

    The treatment of deep anterior crossbite is technically challenging due to the difficulty of placing traditional brackets with fixed appliances. This case report represents a none traditional treatment modality to treat deep anterior crossbite in an adult pseudo class III malocclusion complicated by severely retruded, supraerupted upper and lower incisors. Treatment was carried out in 2 phases. Phase I treatment was performed by removable appliance "modified Hawley appliance with inverted labial bow," some modifications were carried out to it to suit the presented case. Positive overbite and overjet was accomplished in one month, in this phase with minimal forces exerted on the lower incisors. Whereas, phase II treatment was performed with fixed appliances (braces) to align teeth and have proper over bite and overjet and to close posterior open bite, this phase was accomplished within 11 month. PMID:27052290

  6. Pseudo Class III malocclusion

    Science.gov (United States)

    Al-Hummayani, Fadia M.

    2016-01-01

    The treatment of deep anterior crossbite is technically challenging due to the difficulty of placing traditional brackets with fixed appliances. This case report represents a none traditional treatment modality to treat deep anterior crossbite in an adult pseudo class III malocclusion complicated by severely retruded, supraerupted upper and lower incisors. Treatment was carried out in 2 phases. Phase I treatment was performed by removable appliance “modified Hawley appliance with inverted labial bow,” some modifications were carried out to it to suit the presented case. Positive overbite and overjet was accomplished in one month, in this phase with minimal forces exerted on the lower incisors. Whereas, phase II treatment was performed with fixed appliances (braces) to align teeth and have proper over bite and overjet and to close posterior open bite, this phase was accomplished within 11 month. PMID:27052290

  7. Experiencing a Flipped Mathematics Class

    OpenAIRE

    Larsen, A. Judy

    2013-01-01

    The flipped classroom is an old concept that has recently been redefined through the emergence of new technologies that allow teachers to deliver content out of class time. As such, various approaches for implementation exist. Most prominently, teachers are able to use class time in a student-centered manner, which allows students to experience the classroom in diverse ways. This study focuses on describing these experiences in a particular flipped adult upgrading mathematics class. Students ...

  8. Class Differences in Cohabitation Processes

    OpenAIRE

    Sassler, Sharon; Miller, Amanda J.

    2011-01-01

    Despite the burgeoning cohabitation literature, research has failed to examine social class variation in processes of forming and advancing such unions. Drawing upon in-depth interviews with 122 working- and middle-class cohabitors, we examine the duration between dating and moving in together, reasons for cohabiting, and subsequent plans. Transitions to cohabitation are more rapid among the working class. Respondents often cohabited for practical reasons—out of financial necessity, because i...

  9. Professional Elites in "Classes" Societies

    OpenAIRE

    2003-01-01

    Modern European identity has been forged in class struggles between the French revolution and fall of the Berlin Wall, which fell twice. Once, with the rest of the city in May 1945, when a national socialist alternative to a modernizing mix of parliamentary democracy and market economy crumbled after the hot WWII, and second time in November 1989, when a state socialist alternative crumbled after the Cold War. At the same time working class in the USA abandoned trade unions and class struggle...

  10. Reconciling Virtual Classes with Genericity

    DEFF Research Database (Denmark)

    Ernst, Erik

    classes. As a result, a kind of type parameters have been introduced, but they are simple and only used where they excel. Conversely, final definitions of virtual classes have been re- moved from the language, thus making virtual classes more flexible. The result- ing language presents a clearer and more...... flexible trade-off between extensibility and predictability, empowering programmers to choose the right balance....

  11. First class models from linear and nonlinear second class constraints

    Science.gov (United States)

    Dehghani, Mehdi; Mardaani, Maryam; Monemzadeh, Majid; Nejad, Salman Abarghouei

    2015-10-01

    Two models with linear and nonlinear second class constraints are considered and gauged by embedding in an extended phase space. These models are studied by considering a free non-relativistic particle on the hyperplane and hypersphere in the configuration space. The gauged theory of the first model is obtained by converting the very second class system to the first class one directly. In contrast, the first class system related to the free particle on the hypersphere is derived with the help of the infinite Batalin-Fradkin-Tyutin (BFT) embedding procedure. We propose a practical formula, based on the simplified BFT method, which is practical in gauging linear and some nonlinear second class systems. As a result of gauging these two models, we show that in the conversion of second class constraints to the first class ones, the minimum number of phase space degrees of freedom for both systems is a pair of phase space coordinates. This pair is made up of a coordinate and its conjugate momentum for the first model, but the corresponding Poisson structure of the embedded non-relativistic particle on hypersphere is a nontrivial one. We derive infinite correction terms for the Hamiltonian of the nonlinear constraints and an interacting gauged Hamiltonian is constructed by summing over them. At the end, we find an open algebra for three first class objects of the embedded nonlinear system.

  12. Class Counts: Education, Inequality, and the Shrinking Middle Class

    Science.gov (United States)

    Ornstein, Allan

    2007-01-01

    Class differences and class warfare have existed since the beginning of western civilization, but the gap in income and wealth between the rich (top 10 percent) and the rest has increased steadily in the last twenty-five years. The U.S. is heading for a financial oligarchy much worse than the aristocratic old world that our Founding Fathers feared…

  13. The Paradox of Paperless Classes.

    Science.gov (United States)

    Lackie, Paula

    1998-01-01

    Describes paperless classes developed at Carleton College that augment traditional classes by giving students and faculty the ability to share digital course-related materials via the campus computer network. Presents a case study of a managerial economics course, and includes problems with various aspects of the course and solutions. (LRW)

  14. Class, Identity, and Teacher Education

    Science.gov (United States)

    Van Galen, Jane A.

    2010-01-01

    This paper explores the possibilities of working with White, working-class teacher education students to explore the "complex social trajectory" (Reay in Women's Stud Int Forum 20(2):225-233, 1997a, p. 19) of class border crossing as they progress through college. Through analysis of a course that I have developed, "Education and the American…

  15. Social Class and the Extracurriculum

    Science.gov (United States)

    Barratt, Will

    2012-01-01

    Social class is a powerful and often unrecognized influence on student participation in the extracurriculum. Spontaneous student-created extracurricular experiences depend on students affiliating and interacting with each other; student social class is a powerful influence on student affiliations. Students tend to exercise consciousness of kind-…

  16. A Touch of...Class!

    Science.gov (United States)

    Netten, Joan W., Ed.

    1984-01-01

    A collection of ideas for class activities in elementary and secondary language classes includes a vocabulary review exercise and games of memory, counting, vocabulary, flashcard tic-tac-toe, dice, trashcans, questioning, and spelling. Some are designed specifically for French. (MSE)

  17. Class Differences in Cohabitation Processes

    Science.gov (United States)

    Sassler, Sharon; Miller, Amanda J.

    2011-01-01

    Despite the burgeoning cohabitation literature, research has failed to examine social class variation in processes of forming and advancing such unions. Drawing upon in-depth interviews with 122 working- and middle-class cohabitors, we examine the duration between dating and moving in together, reasons for cohabiting, and subsequent plans.…

  18. The Generalizability of Class Means

    Science.gov (United States)

    Kane, Michael T.; Brennan, Robert L.

    1977-01-01

    Dependability of class means is analyzed by applying generalizability to a split-plot design with students nested within classes. Basic generalizability concepts are reviewed, and the derivation and interpretation of distinct generalizability concepts are discussed. Four generalizability coefficients are compared with each other and with the three…

  19. Student Engagement and Marketing Classes

    Science.gov (United States)

    Taylor, Steven A.; Hunter, Gary L.; Melton, Horace; Goodwin, Stephen A.

    2011-01-01

    A study is reported that investigates the goals underlying undergraduate students' engagement in their major classes, nonmajor classes, and in extracurricular activities. The qualitative study employs both focus groups and goal-mapping exercises. The results suggest that students tend to focus on utilitarian, attribute-level considerations mainly…

  20. Predicting Acoustics in Class Rooms

    DEFF Research Database (Denmark)

    Christensen, Claus Lynge; Rindel, Jens Holger

    2005-01-01

    Typical class rooms have fairly simple geometries, even so room acoustics in this type of room is difficult to predict using today's room acoustic computer modeling software. The reasons why acoustics of class rooms are harder to predict than acoustics of complicated concert halls might be...

  1. Dynamic class methods in Java

    OpenAIRE

    Heinlein, Christian

    2005-01-01

    The concept of dynamic class methods in Java, constituting a specialization of a general new programming language concept called dynamic routines, is introduced and applied to a simple case study. Its advantages over standard object-oriented programming techniques including design patterns are demonstrated. Furthermore, an implementation of dynamic class methods as a precompiler-based language extension to Java is described.

  2. Control Class Summaries and Control Class IV from April 1990

    Energy Technology Data Exchange (ETDEWEB)

    Wu, J.; /Fermilab

    1991-02-22

    The D0 cryogenic control system is a complicated system with many facets. Because of the large number and variety of features in the system, a series of ongoing control system training seminars, or control classes, were created in order to keep people up to date on the operation of the system. As of the writing of this engineering note, there have been four classes. The original lecture notes from each class can be found in the cryogenic control room at the D0 Assembly Building, or in the Co-op office. This note provides a summary of the first three control classes, and it includes the entire set of notes from the fourth class, which was held in April of 1990. This class was taught by Jeff Wendlandt and Dan Markley. Dan should be consulted for more complete explanations than those given in the notes. The notes are, in fact, more of a reference for someone who has some experience with the system, than they are a training manual. Most of the pages include pictures and printouts of different menus and functions, useful for finding details without searching through the actual program. In general, this note serves as a pointer to the existence of the control class lecture notes, and as an explanation of their overall contents and purpose.

  3. First class models from linear and nonlinear second class constraints

    CERN Document Server

    Dehghani, Mehdi; Monemzadeh, Majid; Abarghooeinejad, Salman

    2014-01-01

    Two models with linear and nonlinear second class constraints are considered and gauged by embedding in an extended phase space. These models are the free non-relativistic particle on a hyperplane and hyper sphere in configuration space. For the first model we construct its gauged corresponding by the condition of converting second class system to first class one, directly. In contrast the first class system related to the free particle on hyper sphere is derived by the BFT embedding procedure, where its steps are infinite. We give a practical formula for gauging linear and some of the nonlinear second class systems, based on the simplified BFT method. As a result of the gauging two models, we show that in the conversion of second class to the first class constraints the minimum number of phase space degrees of freedom for both systems is a pair of phase space coordinate. This pair for first system is a coordinate and its momentum conjugate, but Poisson structure of embedded non-relativistic particle on hyper...

  4. Class in Metropolitan India: The Rise of the Middle Classes

    OpenAIRE

    Mooij, Jos; Lama-Rewal, S.T.

    2009-01-01

    textabstractIt is almost a cliché to say that India’s appearance and image (internationally as well as self-image) have changed dramatically in the last fifteen years. Instead of being associated with rural poverty, India is now associated with high rates of economic growth, a booming Information Technology (IT) sector and, particularly, an increasingly expanding middle class that consumes and behaves like elites and middle classes elsewhere in the world. Considering that cities concentrate m...

  5. New Ramsey Classes from Old

    CERN Document Server

    Bodirsky, Manuel

    2012-01-01

    Let C_1 and C_2 be strong amalgamation classes of finite structures, with disjoint finite signatures sigma and tau. Then C_1 wedge C_2 denotes the class of all finite (sigma cup tau)-structures whose sigma-reduct is from C_1 and whose tau-reduct is from C_2. We prove that when C_1 and C_2 are Ramsey, then C_1 wedge C_2 is also Ramsey. We also discuss variations of this statement, and give several examples of new Ramsey classes derived from those general results.

  6. Second class currents and nuclei

    International Nuclear Information System (INIS)

    A theoretical analysis of the recent experimental data relevant to second-class currents is made on the basis of the effective two-body operator approach proposed several years ago by the present authors. It takes into account nuclear many-body effects such as off-the-energy-shell and meson-exchange effects. The previous results indicating the presence of second-class currents comparable in their magnitudes to the weak magnetism term are altered. Next, we suggest that mesonic effects on the time-component of first-class axial current can be tested unambiguously. The argument is based on the low-energy theorem and model-independent to great degree. We emphasize that further correlation experiments are highly desirable not only for testing the second-class currents but also making a clean test of the mesonic effects on axial current. (author)

  7. Integrals of the Ising Class

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, David H.; Borwein, Jonathan M.; Crandall, Richard E.

    2006-06-01

    From an experimental-mathematical perspective we analyze"Ising-class" integrals. Our experimental results involvedextreme-precision, multidimensional quadrature on intricate integrands;thus, highly parallel computation was required.

  8. Class attendance and university performance

    OpenAIRE

    Hoffmann, Anna-Lena; Lerche, Katharina

    2016-01-01

    Using survey data collected at Göttingen University, Germany, this paper evaluates the effect of attending the lecture and/or tutorial on the grade achieved in two basic courses in business administration and economics. The analysis shows that going to class has no significant impact on student performance in most specifications. Although the identification of a causal effect may not be possible with the data at hand, the results suggest that, in the given framework, attending class and study...

  9. Whole Class Laboratories: More Examples

    Science.gov (United States)

    Kouh, Minjoon

    2016-03-01

    Typically, introductory physics courses are taught with a combination of lectures and laboratories in which students have opportunities to discover the natural laws through hands-on activities in small groups. This article reports the use of Google Drive, a free online document-sharing tool, in physics laboratories for pooling experimental data from the whole class. This pedagogical method was reported earlier, and the present article offers a few more examples of such "whole class" laboratories.

  10. Internet service classes under competition

    OpenAIRE

    Gibbens, R.; R. Mason; Steinberg, Richard

    2000-01-01

    This paper analyzes competition between two Internet service providers (ISPs), either or both of which may choose to offer multiple service classes. In the model analyzed, a social planner who maximizes the total benefit from network usage and a profit maximizing monopolist will both form multiple service classes; but two networks competing to maximize profits will not. The reason is that a competition effect always outweighs a segmentation effect. Networks wish to offer multiple service clas...

  11. Less than a Class Set

    Science.gov (United States)

    Bennett, Kristin Redington

    2012-01-01

    The iPad holds amazing potential for classroom use. Just a few--or even only one--is enough to get results. Having a class set promotes traditional, whole-class instruction, but fewer iPads facilitate individualized and tailored instruction. In this article, the author discusses the potential of the iPad and suggests ways to put the iPad to use in…

  12. Polynomial Operators on Classes of Regular Languages

    Science.gov (United States)

    Klíma, Ondřej; Polák, Libor

    We assign to each positive variety mathcal V and each natural number k the class of all (positive) Boolean combinations of the restricted polynomials, i.e. the languages of the form L_0a_1 L_1a_2dots a_ell L_ell, text{ where } ell≤ k, a 1,...,a ℓ are letters and L 0,...,L ℓ are languages from the variety mathcal V. For this polynomial operator we give a certain algebraic counterpart which works with identities satisfied by syntactic (ordered) monoids of languages considered. We also characterize the property that a variety of languages is generated by a finite number of languages. We apply our constructions to particular examples of varieties of languages which are crucial for a certain famous open problem concerning concatenation hierarchies.

  13. A New Complete Class Complexity Metric

    OpenAIRE

    Singh, Vinay; Bhattacherjee, Vandana

    2014-01-01

    Software complexity metrics is essential for minimizing the cost of software maintenance. Package level and System level complexity cannot be measured without class level complexity. This research addresses the class complexity metrics. This paper studies the existing class complexity metrics and proposes a new class complexity metric CCC (Complete class complexity metric). The CCC metric is then analytically evaluated by Weyuker's property.

  14. Classes subalternas, lutas de classe e hegemonia: uma abordagem gramsciana Subaltern classes, class struggles and hegemony: a gramscian approach

    Directory of Open Access Journals (Sweden)

    Ivete Simionatto

    2009-06-01

    Full Text Available O artigo procura resgatar, no pensamento de Antonio Gramsci, a concepção de classes subalternas e a sua relação com outras categorias, especialmente, o Estado, a sociedade civil e a hegemonia, como suportes da luta de classes na realidade contemporânea. Aborda, ainda, as relações entre classes subalternas, senso comum e ideologia, bem como as formas de superação tematizadas por Gramsci, através da cultura e da filosofia da práxis. Nesse sentido, num movimento de totalidade, busca recuperar a discussão das classes subalternas, a partir da original formulação gramsciana no âmbito do marxismo, mediante a interação dialética entre estrutura e superestrutura, economia e política. Além do resgate conceitual, apontam-se alguns elementos como subsídios à discussão das formas de subalternidade presentes na realidade contemporânea e as possibilidades de fortalecimento das lutas de tais camadas de classe, sobretudo em momentos de forte desmobilização da participação popular.This article sought to revive the concept of subaltern classes and their relation with other categories, particularly the State, civil society and hegemony in the thinking of Antonio Gramsci, as a support for contemporary class struggles. It also analyzes the relations between subaltern classes, common sense and ideology, as well as the forms of "overcoming" conceptualized by Gramsci, through the culture and philosophy of praxis. The paper revives the discussion of the subaltern classes, based on the original Gramscian formulation in the realm of Marxism, through the dialectic interaction between structure and superstructure, economy and politics. In addition to the conceptual revival, it indicates some elements that can support the discussion of the forms of subalternity found in contemporary reality and the possibilities for strengthening the struggles of these class layers, above all in moments of strong demobilization of popular participation.

  15. Design of Class-E Radio Frequency Power Amplifier

    OpenAIRE

    Al-Shahrani, Saad Mohammed

    2000-01-01

    Power amplifiers (PA) are typically the most power-consuming building blocks of RF transceivers. Therefore, the design of a high-efficiency radio frequency power amplifier is the most obvious solution to overcoming the battery lifetime limitation in the portable communication systems. A power amplifierà ­s classes (A, AB, B, C, F, E, etc), and design techniques (Load-pull and large-signal S-parameters techniques) are presented. The design accuracy of class-A power amplifier based on the s...

  16. High Power Wideband Class-E Power Amplifier

    OpenAIRE

    Ortega González, Francisco Javier

    2010-01-01

    This letter shows a high-power, high-efficiency, wideband Class-E RF power amplifier designed upon the load admittance synthesis concept and built using an uncomplicated low-loss load network with a low loss wideband admittance transformer as the main component. It uses a power Silicon LDMOS transistor to provide up to 145 W at 28 V peak power, up to 86% drain efficiency over 35% fractional bandwidth (from 85 to 120 MHz) and 15.6 dB gain at peak power without any adjustments. These are clear ...

  17. Towards a Class Struggle Anthropology

    Directory of Open Access Journals (Sweden)

    Charles R. Menzies

    2007-05-01

    Full Text Available Dancing between review and argument this paper lays out a foundation for a class-struggle anthropology -that is, an anthropological practice that can be linked to the ultimate goal of achieving a classless society. To this end we will review those anthropologists who have gone before us, pulling out those works of theirs that we see as critical in (rebuilding a class-struggle anthropology. As part of this process we discuss the relationship between what has stood as Marxist anthropology in North America, the idea of socialism, the political development of the world working class during nine decades since the October Revolution, and the challenges of intellectual continuity in the face of differing generational experiences of Marxist anthropologists. Ultimately we argue that a progressive anthropology necessarily involves political activism in our work, communities, and schools.

  18. Using Alternative Assessments in Business and Foreign Language Classes

    Science.gov (United States)

    Gill, Deborah; Lucas, Diane

    2013-01-01

    The present study will be divided in three parts: (1) a discussion of authentic alternative assessments vs. traditional assessments in language and business classes; (2) an explanation on how to create authentic alternative assessments using technology-based and non-technology-based materials; and (3) tools to evaluate these authentic assessments.…

  19. A library of function classes

    International Nuclear Information System (INIS)

    We have written a library of function classes in C++, which is distributed as part of the CLHEP foundation class libraries for High Energy Physics. The main goals of the library are to provide objects having all the mathematical behavior of functions, and to provide a mechanism for parameterizing these functions. Our functions support all the normal function operations such as addition, subtraction, multiplication, division, composition, et. cetera. The library allows programmers to compose complicated one-or multi-dimensional functions with great economy and natural semantics

  20. Professional Elites in "Classes" Societies

    OpenAIRE

    Magala, Slawomir

    2003-01-01

    textabstractModern European identity has been forged in class struggles between the French revolution and fall of the Berlin Wall, which fell twice. Once, with the rest of the city in May 1945, when a national socialist alternative to a modernizing mix of parliamentary democracy and market economy crumbled after the hot WWII, and second time in November 1989, when a state socialist alternative crumbled after the Cold War. At the same time working class in the USA abandoned trade unions and cl...

  1. On uniqueness of characteristic classes

    DEFF Research Database (Denmark)

    Feliu, Elisenda

    2011-01-01

    We give an axiomatic characterization of maps from algebraic K-theory. The results apply to a large class of maps from algebraic K-theory to any suitable cohomology theory or to algebraic K-theory. In particular, we obtain comparison theorems for the Chern character and Chern classes and for the...... Adams operations and ¿-operations on higher algebraic K-theory. We show that the Adams operations and ¿-operations defined by Grayson agree with the ones defined by Gillet and Soulé....

  2. Moran sets and Moran classes

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The purpose of this survey is to present Moran sets and Moran classes which generalize the classical selfsimilar sets from the following points: ( i ) The placements of the basic sets at each step of the constructions can be arbitrary; (ii) the contraction ratios may be different at each step; and (iii) the lower limit of the contraction ratios permits zero. In this discussion we will present geometrical properties and results of dimensions of these sets and classes,and discuss conformal Moran sets and random Moran sets as well.``

  3. Achieving world class maintenance status

    Energy Technology Data Exchange (ETDEWEB)

    Tomlingson, P.D. [Paul D. Tomingson Associates (United States)

    2007-08-15

    The article written by a management consultant, discusses the art of successful planning and operation of maintenance in mines considering factors such as benchmaking, key performance indices (KPIs) and frequency of procedures which can help achieve 'world class maintenance'. 1 fig.

  4. Social Class and School Music

    Science.gov (United States)

    Bates, Vincent C.

    2012-01-01

    This article takes a practical look at social class in school music by exploring the manifestations and impact of three of its dimensions: financial resources, cultural practices, and social networks. Three suggestions are discussed: provide a free and equal music education for all students, understand and respect each student's cultural…

  5. A Class of Graceful Trees

    Institute of Scientific and Technical Information of China (English)

    孟凡洪; 苏耕; 杨继

    2000-01-01

    The present paper shows the coordinates of a tree and its vertices, defines a kind of Trees with Odd-Number Radiant Type (TONRT), deals with the gracefulness of TONRT by using the edge-moving theorem, and uses graceful TONRT to construct another class of graceful trees.

  6. COOPERATIVE LEARNING IN LARGE CLASSES

    Institute of Scientific and Technical Information of China (English)

    GuoXiangju

    2004-01-01

    Teaching college English in large classes is a new challenge to teachers. To meet this challenge, the strategy of cooperative learning is practicable. This paper introduces cooperative learning and describes the experiment results, which prove the advantages of cooperative learning over competitive learning or individualistic learning.

  7. Active Learning in Large Classes

    DEFF Research Database (Denmark)

    Gørtz, Inge Li

    2011-01-01

    teaching large classes (more than 50 students), and describe how we successfully have in a second semester course in the Bachelor of Engineering (BEng) and Bachelor of Science Engineering (BSc Eng) program at the Technical University of Denmark (DTU). Approximately 200 students is attending the...

  8. Active Learning in Large Classes

    DEFF Research Database (Denmark)

    Gørtz, Inge Li

    2011-01-01

    lectures in the course. The main idea is to use inductive, case-based learning, with many small exercises/ discussions during the lectures. We describe a framework for the lectures, that most lectures in the class were based on. The framework contains the conceive, design, and implement stage from the CDIO...

  9. "Green" Classes Flourish in Schools

    Science.gov (United States)

    Cavanagh, Sean

    2009-01-01

    Courses focused on renewable and alternative energy are taking hold across the country as educators seek to channel students' concerns about the environment and conservation into classroom lessons. This article talks about the rising interest in "green" curriculum. Here, the author describes the Green Tech class that introduces students to the…

  10. Art of Class Teaching Encourage

    Institute of Scientific and Technical Information of China (English)

    HE Jiao-fei

    2013-01-01

    Teaching encourage can lead to student’s learning motivation and interesting. It improves the effect of classroom teach⁃ing. Methods of class teaching inspiration are: Target encourage, expectation encourage, emotional encourage, positive encourage, attribution encourage, competition encourage, caress encourage, democracy encourage, praise encourage, time encourage, check en⁃courage, questions encourage, examination encourage, score encourage, example encourage and understanding encourage.

  11. Creative Thinking in Instrumental Classes.

    Science.gov (United States)

    Priest, Thomas

    2002-01-01

    Focuses on ways to develop student creative thinking, improvisation, and composition skills in instrumental classes. Provides suggestions, such as the importance of offering students creative opportunities, supplying examples, giving control to students, and encouraging expressive integrity. Includes a bibliography of resources for developing…

  12. Student versus Faculty Perceptions of Missing Class.

    Science.gov (United States)

    Sleigh, Merry J.; Ritzer, Darren R.; Casey, Michael B.

    2002-01-01

    Examines and compares student and faculty attitudes towards students missing classes and class attendance. Surveys undergraduate students (n=231) in lower and upper level psychology courses and psychology faculty. Reports that students found more reasons acceptable for missing classes and that the amount of in-class material on the examinations…

  13. Education, Social Class and Social Exclusion.

    Science.gov (United States)

    Whitty, Geoff

    2001-01-01

    Concerned about working-class failure, argues that recent (British) government policies have insufficiently considered sociological studies on how social class affects educational success or failure. Social-inclusion policies must address forms of middle-class self-exclusion from mainstream public education as well as working-class social…

  14. Making the Introductory Journalism Class Tick.

    Science.gov (United States)

    Dorway, Tim

    2003-01-01

    Proposes that beginning journalism classes teach multiple skills, including law, decision-making, interpersonal communication, interviewing, and critical thinking. Outlines how to convince administrators of the need for beginning journalism classes, and how to develop an effective class. Lists philosophy and course goals for one such class. (PM)

  15. BDDCS Class Prediction for New Molecular Entities

    DEFF Research Database (Denmark)

    Broccatelli, Fabio; Cruciani, Gabriele; Benet, Leslie Z.;

    2012-01-01

    the prediction, which showed highest accuracy in predicting classes 2 and 3 with respect to the most populated class 1. For class 4 drugs a general lack of predictability was observed. A linear discriminant analysis (LDA) confirming the degree of accuracy for the prediction of the different BDDCS classes is tied...

  16. Trabalho e classes sociais Work and social classes

    Directory of Open Access Journals (Sweden)

    Fernando Haddad

    1997-10-01

    Full Text Available Exposição, discussão e refutação das principais tentativas de atualizar a teoria marxista de classes e posterior reavaliação dessa teoria à luz da transformação da ciência em fator de produção e da possível perda de centralidade do trabalho no processo produtivo, tendo por base as interpretações lógicas da obra de Marx feitas por Ruy Fausto.Exposition, discussion and refutation of the main attempts of actualizing marxist class theory and a posterior reevaluation of this theory taking into account the transformation of Science into a factor of production and of the possible centrality-loss of work in the productive process, based on the logic interpretations of Marx's work made by Ruy Fausto.

  17. Monetarism Beyond M1A

    OpenAIRE

    Pablo García; Rodrigo O. Valdés

    2004-01-01

    This work analyzes, from an empirical standpoint, the information contained in the M1A aggregate in Chile and compares it with other aggregates. The findings reveal that, at least for now, the M1A aggregate does not seem to have particularly valuable information that would make it a better indicator of inflationary pressures within the monetary policy decision horizon. This is consistent with the practice that central banks followed in the past, when they used quantitative targets for money a...

  18. Stochastic prediction of drought class transitions

    OpenAIRE

    Paulo, Ana A.; L. S. Pereira

    2008-01-01

    This paper aims at the stochastic characterization of droughts applying Markov chains modeling to drought class transitions derived from SPI time series. Several sites in Southern Portugal having updated data on precipitation available were considered. The drought class probabilities, the expected residence time in each class of severity, the expected time for the transition between drought classes and the drought severity class predictions 1, 2, or 3 months ahead have been obt...

  19. Understanding Intra-Class Knowledge Inside CNN

    OpenAIRE

    Wei, Donglai; Zhou, Bolei; Torrabla, Antonio; Freeman, William

    2015-01-01

    Convolutional Neural Network (CNN) has been successful in image recognition tasks, and recent works shed lights on how CNN separates different classes with the learned inter-class knowledge through visualization. In this work, we instead visualize the intra-class knowledge inside CNN to better understand how an object class is represented in the fully-connected layers. To invert the intra-class knowledge into more interpretable images, we propose a non-parametric patch prior upon previous CNN...

  20. ¿Quiénes dirigen las instituciones educativas en Cali? Perfil de los directivos docentes en colegios públicos y privados de estratos 1 a 4 Quem dirige as instituições educativas em Cali? Peril dos diretores docentes em colégios públicos e particulares de classes baixa e média Who Runs the schools in Cali? A Proile of Public and Private School Administrators in Lower Income Areas

    Directory of Open Access Journals (Sweden)

    Norbella Miranda

    2011-12-01

    Full Text Available El objetivo de este artículo es proveer una descripción del perfil de los administradores de la educación que laboran en instituciones públicas y privadas de educación básica y media de estratos 1 a 4 en la ciudad de Santiago de Cali, a través de los rasgos demográficos, socioeconómicos, académicos y profesionales. El artículo es producto de una investigación sobre las condiciones de implementación de la política educativa colombiana Programa Nacional de Bilingüismo. Para el estudio se empleó una encuesta que fue respondida por 70 administradores escolares de 46 instituciones educativas de la ciudad. Los resultados mostraron que el perfil típico del administrador escolar corresponde a mujeres entre los 50y 60 años que tuvieron contacto con el idioma inglés durante sus estudios de básica secundaria, tienen título de Especialización como máximo nivel de formación alcanzado y cuentan con experiencia profesional superior a 11 años. Se hallaron diferencias entre los sectores público y privado: en el primero los directivos tienen un nivel más alto de formación académica y mejores salarios. Los resultados sugieren que se necesita mayor apoyo a la formación de los directivos del sector privado y un mejor reconocimiento económico a la labor desempeñada por los directivos docentes en ambos sectores.O objetivo deste artigo é prover uma descrição do perfil dos administradores da educação que trabalham em instituições públicas e particulares de educação básica e média de classes baixa e média na cidade de Santiago de Cali, por meio dos traços demográficos, socioeconómicos, acadêmicos e profissionais. O artigo é produto de uma pesquisa sobre as condições de implementação da política educativa colombiana Programa Nacional de Bilinguismo. Para o estudo, empregou-se uma enquete que foi respondida por 70 administradores escolares de 46 instituições educativas da cidade. Os resultados mostraram que o perfil

  1. A Transformer Class E Amplifier

    Directory of Open Access Journals (Sweden)

    Mikolajewski Miroslaw

    2014-12-01

    Full Text Available In a high-efficiency Class E ZVS resonant amplifier a matching and isolation transformer can replace some or even all inductive components of the amplifier thus simplifying the circuit and reducing its cost. In the paper a theoretical analysis, a design example and its experimental verification for a transformer Class E amplifier are presented. In the experimental amplifier with a transformer as the only inductive component in the circuit high efficiency ηMAX = 0.95 was achieved for supply voltage VI = 36 V, maximum output power POMAX = 100 W and the switching frequency f = 300 kHz. Measured parameters and waveforms showed a good agreement with theoretical predictions. Moreover, the relative bandwidth of the switching frequency was only 19% to obtain output power control from 4.8 W to POMAX with efficiency not less than 0.9 in the regulation range.

  2. The Fermilab physics class library

    International Nuclear Information System (INIS)

    The Fermilab Physics Class Library Task Force has been formed to supply classes and utilities, primarily in support of efforts by CDF and D0 toward using C++. A collection of libraries and tools will be assembled via development by the task force, collaboration with other HEP developers, and acquisition of existing modules. The main emphasis is on a kit of resources which physics coders can incorporate into their programs, with confidence in robustness and correct behavior. The task force is drawn from CDF, DO and the FNAL Computing and Beams Divisions. Modules-containers, linear algebra, histograms, etc.-have been assigned priority, based on immediate Run II coding activity, and will be available at times ranging from now to late May

  3. Exploitation and the class struggle

    OpenAIRE

    Juan Carlos Cuestas; Bruce Philp

    2010-01-01

    This paper contributes to our understanding of the determinants and dynamics of Marxian exploitation using quarterly UK data, 1955-2008. Initially a simple model is introduced for the purpose of defining exploitation and its component parts, before elaborating on theoretical issues which are important in estimating the rate of exploitation. In the empirical analysis we seek to explain the effect of class struggle, for the UK economy, using quarterly data. Attention is paid to three forces whi...

  4. Promoting Wellness in Lamaze Classes

    OpenAIRE

    Hotelling, Barbara A.

    2005-01-01

    Lamaze childbirth educators are responsible for teaching wellness-based classes that do not add to the anxiety of the current, fear-based culture of maternity health care. Expectant parents' vulnerable months of pregnancy offer “teachable moments” for the childbirth educator, during which parents can be encouraged to alter their lifestyles and adopt the concept of wellness to their principles of living. In this article, concepts of wellness are examined, drawing from the writings of wellness ...

  5. Entropic One-Class Classifiers.

    Science.gov (United States)

    Livi, Lorenzo; Sadeghian, Alireza; Pedrycz, Witold

    2015-12-01

    The one-class classification problem is a well-known research endeavor in pattern recognition. The problem is also known under different names, such as outlier and novelty/anomaly detection. The core of the problem consists in modeling and recognizing patterns belonging only to a so-called target class. All other patterns are termed nontarget, and therefore, they should be recognized as such. In this paper, we propose a novel one-class classification system that is based on an interplay of different techniques. Primarily, we follow a dissimilarity representation-based approach; we embed the input data into the dissimilarity space (DS) by means of an appropriate parametric dissimilarity measure. This step allows us to process virtually any type of data. The dissimilarity vectors are then represented by weighted Euclidean graphs, which we use to determine the entropy of the data distribution in the DS and at the same time to derive effective decision regions that are modeled as clusters of vertices. Since the dissimilarity measure for the input data is parametric, we optimize its parameters by means of a global optimization scheme, which considers both mesoscopic and structural characteristics of the data represented through the graphs. The proposed one-class classifier is designed to provide both hard (Boolean) and soft decisions about the recognition of test patterns, allowing an accurate description of the classification process. We evaluate the performance of the system on different benchmarking data sets, containing either feature-based or structured patterns. Experimental results demonstrate the effectiveness of the proposed technique. PMID:25879977

  6. Social Identity and Class Consciousness

    OpenAIRE

    Hanappi, Hardy; Hanappi-Egger, Edeltraud

    2014-01-01

    The current economic crisis proves how deep the contradictions inherent in contemporary capitalism really are. At the same time it is evident that the financial crisis goes hand in hand with a social crisis, since an increasing number of people lost trust in governments, trade unions and other representative institutions. A main reason why the European Left nevertheless faces severe challenges in attracting supporters seems to be an experienced loss of what has been called ‘working class ...

  7. 32 CFR 1630.15 - Class 1-H: Registrant not subject to processing for induction.

    Science.gov (United States)

    2010-07-01

    ... for induction. 1630.15 Section 1630.15 National Defense Other Regulations Relating to National Defense... induction. In Class 1-H shall be placed any registrant who is not eligible for Class 1-A and is not currently subject to processing for induction....

  8. Physical characteristics of bright Class I methanol masers

    Science.gov (United States)

    Leurini, S.; Menten, K. M.; Walmsley, C. M.

    2016-07-01

    44 GHz line is almost always stronger than the 36 GHz maser. By comparison between observed isotropic photon luminosities and our model predictions, we infer maser beam solid angles of roughly 10-3 steradian. Conclusions: We find that the Class I masers can reasonably be separated into three families: the (J + 1)-1-J0-E type series, the (J + 1)0-J1-A type, and the J2-J1-E lines at 25 GHz. The 25 GHz lines behave in a different fashion from the other masers as they are only inverted at high densities above 106 cm-3 in contrast to other Class I masers. Therefore, the detection of maser activity in all three families is a clear indication of high densities.

  9. Main: PYRIMIDINEBOXOSRAMY1A [PLACE

    Lifescience Database Archive (English)

    Full Text Available PYRIMIDINEBOXOSRAMY1A S000259 19-August-2004 (last modified) kehi Pyrimidine box found in rice ( ... GARE and pyrimidine box are partially involved in sugar ... repression; Found in the promoter of barley alpha- ... ifically to this site; See S000265; alpha-amylase; sugar ... repression; GARE; pyrimidine box; feed-back metabo ...

  10. Do class size effects differ across grades?

    DEFF Research Database (Denmark)

    Nandrup, Anne Brink

    size cap that creates exogenous variation in class sizes. Significant (albeit modest) negative effects of class size increases are found for children on primary school levels. The effects on math abilities are statistically different across primary and secondary school. Larger classes do not affect......This paper contributes to the class size literature by analyzing whether short-run class size effects are constant across grade levels in compulsory school. Results are based on administrative data on all pupils enroled in Danish public schools. Identification is based on a government-imposed class...

  11. Flowability of JSC-1a

    Science.gov (United States)

    Rame, Enrique; Wilkinson, Allen; Elliot, Alan; Young, Carolyn

    2009-01-01

    We have done a complete flowability characterization of the lunar soil simulant, JSC-1a, following closely the ASTM-6773 standard for the Schulze ring shear test. The measurements, which involve pre-shearing the material before each yield point, show JSC-1a to be cohesionless, with an angle of internal friction near 40 deg. We also measured yield loci after consolidating the material in a vibration table which show it to have significant cohesion (approximately equal to 1 kPa) and an angle of internal friction of about 60 deg. Hopper designs based on each type of flowability test differ significantly. These differences highlight the need to discern the condition of the lunar soil in the specific process where flowability is an issue. We close with a list not necessarily comprehensive of engineering rules of thumb that apply to powder flow in hoppers.

  12. First-Class Object Sets

    DEFF Research Database (Denmark)

    Ernst, Erik

    Typically, objects are monolithic entities with a fixed interface. To increase the flexibility in this area, this paper presents first-class object sets as a language construct. An object set offers an interface which is a disjoint union of the interfaces of its member objects. It may also be used...... for a special kind of method invocation involving multiple objects in a dynamic lookup process. With support for feature access and late-bound method calls object sets are similar to ordinary objects, only more flexible. The approach is made precise by means of a small calculus, and the soundness of...

  13. Teacher's Questions in Reading Classes

    OpenAIRE

    Zuliati Rohmah

    2002-01-01

    Abstract: The present paper discusses an English teacher's questions in Reading classes at MAN Malang III. Types of questions, functions of teacher's questions, question levels and the strategies applied by the teacher were put as the research problems. Non-participant observa­tion was applied to collect the data with the researcher as the main in­strument aided by field-notes and a tape recorder. It was found that the distribution of the questions did not allow the students to talk longer ...

  14. A class of integrable metrics

    Science.gov (United States)

    Anabalón, Andrés; Batista, Carlos

    2016-03-01

    In four dimensions, the most general metric admitting two commuting Killing vectors and a rank-two Killing tensor can be parametrized by ten arbitrary functions of a single variable. We show that picking a special vierbein, reducing the system to eight functions, implies the existence of two geodesic and share-free, null congruences, generated by two principal null directions of the Weyl tensor. Thus, if the spacetime is an Einstein manifold, the Goldberg-Sachs theorem implies it is Petrov type D, and by explicit construction, is in the Carter class. Hence, our analysis provides a straightforward connection between the most general integrable structure and the Carter family of spacetimes.

  15. A Class of Integrable Metrics

    CERN Document Server

    Anabalon, Andres

    2016-01-01

    In four dimensions, the most general metric admitting two Killing vectors and a rank-two Killing tensor can be parameterized by ten arbitrary functions of a single variable. We show that picking a special vierbien, reducing the system to eight functions, implies the existence of two geodesic and share-free, null congruences, generated by two principal null directions of the Weyl tensor. Thus, if the spacetime is an Einstein manifold, the Goldberg-Sachs theorem implies it is Petrov type D, and by explicit construction, is in the Carter class. Hence, our analysis provide an straightforward connection between the most general integrable structure and the Carter family of spacetimes.

  16. Characteristic classes of mixed Hodge modules

    CERN Document Server

    Schuermann, Joerg

    2009-01-01

    This paper gives an introduction and overview about recent developments on the interaction of the theories of characteristic classes and mixed Hodge theory for singular spaces in the complex algebraic context. It uses M. Saito's deep theory of mixed Hodge modules as a "black box", thinking about them as "constructible or perverse sheaves of Hodge structures", having the same functorial calculus of Grothendieck functors. For the "constant Hodge sheaf", one gets the "motivic characteristic classes" of Brasselet-Schuermann-Yokura, whereas the classes of the "intersection homology Hodge sheaf" were studied by Cappell-Maxim-Shaneson. There are two versions of these characteristic classes. The K-theoretical classes capture information about the graded pieces of the filtered de Rham complex of the filtered D-module underlying a mixed Hodge module. Application of a suitable Todd class transformation then gives classes in homology. These classes are functorial for proper pushdown and exterior products, together with s...

  17. A Class of DSm Conditional Rules

    OpenAIRE

    Smarandache, Florentin; Alford, Mark

    2009-01-01

    In this paper we introduce two new DSm fusion conditioning rules with example, and as a generalization of them a class of DSm fusion conditioning rules, and then extend them to a class of DSm conditioning rules.

  18. FDA Bolsters Warnings about Class of Antibiotics

    Science.gov (United States)

    ... html FDA Bolsters Warnings About Class of Antibiotics Fluoroquinolones such as Cipro, Levaquin should be reserved for ... label warnings on a class of antibiotics called fluoroquinolones because the drugs can lead to disabling side ...

  19. Mandatory Class 1 Federal Areas Web Service

    Data.gov (United States)

    U.S. Environmental Protection Agency — This web service contains the following layers: Mandatory Class 1 Federal Area polygons and Mandatory Class 1 Federal Area labels in the United States. The polygon...

  20. Investment Company Series and Class Information

    Data.gov (United States)

    Securities and Exchange Commission — The Series and Class Report provides basic identification information for all active registered investment company series and classes that have been issued IDs by...

  1. Structural complexity metrics for UML class diagrams

    Institute of Scientific and Technical Information of China (English)

    KONG Qing-yan; LUN Li-jun; WANG Yi-he; DING Xue-mei

    2008-01-01

    In order to evaluate the structural complexity of class diagrams systematically and deeply, a new guiding framework of structural complexity is presented. An index system of structural complexity for class dia-grams is given. This article discusses the formal description of class diagrams, and presents the method of for-mally structural complexity metrics for class diagrams from associations, dependencies, aggregations, generali-zations and so on. An applicable example proves the feasibility of the presented method.

  2. What Are Lay Theories of Social Class?

    OpenAIRE

    Varnum, Michael E. W.

    2013-01-01

    Numerous studies have documented the effects of social class on psychological and behavioral variables. However, lay beliefs about how social class affects these dimensions have not been systematically tested. Studies 1 and 2 assessed lay beliefs about the association between social class and 8 variables (including psychological and behavioral tendencies and cognitive ability). Study 3 assessed lay beliefs about the Big five personality traits and social class, and study 4 reframed the 8 vari...

  3. On Thurston's Euler class one conjecture

    OpenAIRE

    Yazdi, Mehdi

    2016-01-01

    In 1976, Thurston proved that taut foliations on closed hyperbolic 3-manifolds have Euler class of norm at most one, and conjectured that, conversely, any Euler class with norm equal to one is Euler class of a taut foliation. We construct counterexamples to this conjecture and suggest an alternative conjecture.

  4. Using Social Class in Counseling Psychology Research

    Science.gov (United States)

    Liu, William Ming; Ali, Saba Rasheed; Soleck, Geoff; Hopps, Joshua; Dunston, Kwesi; Pickett, Theodore

    2004-01-01

    Social class is an important cultural construct, but it is poorly used in research. Problems in using social class may be associated with its poor definition in previous studies; conflating between social class and socioeconomic status; using objective indices such as income, education, and occupation rather than subjective measures; regarding…

  5. Diffusion of Responsibility in College Classes

    Institute of Scientific and Technical Information of China (English)

    李珍珍

    2015-01-01

    Diffusion of responsibility takes place in college classes nowadays.The author points out diffusion of responsibility in college classes,analyses psychological reasons of diffusion of responsibility,and gives strategies on avoiding the diffusion of responsibility.The paper aims at doing some contribution to improving teaching quality of college class.

  6. The Social Psychology of Class and Classism

    Science.gov (United States)

    Lott, Bernice

    2012-01-01

    In the United States, one is born into a family that can be identified as working class, middle class, or affluent--divisions that denote status and power, as defined by access to resources. This article explores the relationships between social class membership and a wide array of personal and social daily life experiences. It concludes with a…

  7. Application of Class Activities in English Teaching

    Institute of Scientific and Technical Information of China (English)

    刘琦

    2015-01-01

    Beginning with the analysis of present English teaching,the article puts forward some questions occurring in English classes.Then it talks about the necessity of implementing class activities.Finally it further elaborates how to carry out class activities through three specific examples.

  8. Give Your Technology Program a Little "Class"!

    Science.gov (United States)

    Vengersammy, Ormilla

    2009-01-01

    The Orange County Library System (OCLS) began to offer basic technology classes in July 2000. The computers were funded through a grant awarded by the Bill & Melinda Gates Foundation. Over time, the library staff noticed that the demand for the classes increased, so the offering of classes also increased. When the author arrived at OCLS, her main…

  9. Flipping Quantitative Classes: A Triple Win

    Science.gov (United States)

    Swart, William; Wuensch, Karl L.

    2016-01-01

    In the "flipped" class, students use online materials to learn what is traditionally learned by attending lectures, and class time is used for interactive group learning. A required quantitative business class was taught as a flipped classroom in an attempt to improve student satisfaction in the course and reduce the "transactional…

  10. White Middle Class Identities and Urban Schooling

    Science.gov (United States)

    Devine, Dympna; Savage, Mike; Ingram, Nicola

    2012-01-01

    The authors review "White middle class identities and urban schooling," by D. Reay, G. Crozier and D. James. This book focuses on the perspectives of white middle-class parents who make "against"-the-grain school choices for their children in urban England. It provides key insights into the dynamics of class practising that are played out in these…

  11. Intersection numbers with Witten's top Chern class

    NARCIS (Netherlands)

    S. Shadrin; D. Zvonkine

    2008-01-01

    Witten’s top Chern class is a particular cohomology class on the moduli space of Riemann surfaces endowed with r-spin structures. It plays a key role in Witten’s conjecture relating to the intersection theory on these moduli spaces. Our first goal is to compute the integral of Witten’s class over th

  12. Long-term effects of class size

    OpenAIRE

    Fredriksson, Peter; Öckert, Björn; Oosterbeek, Hessel

    2012-01-01

    This paper evaluates the long-term effects of class size in primary school. We use rich data from Sweden and exploit variation in class size created by a maximum class size rule. Smaller classes in the last three years of primary school (age 10 to 13) are beneficial for cognitive and non-cognitive ability at age 13, and improve achievement at age 16. Most importantly, we find that smaller classes have positive effects on completed education, wages, and earnings at age 27 to 42. The estimated ...

  13. Context-sensitive intra-class clustering

    KAUST Repository

    Yu, Yingwei

    2014-02-01

    This paper describes a new semi-supervised learning algorithm for intra-class clustering (ICC). ICC partitions each class into sub-classes in order to minimize overlap across clusters from different classes. This is achieved by allowing partitioning of a certain class to be assisted by data points from other classes in a context-dependent fashion. The result is that overlap across sub-classes (both within- and across class) is greatly reduced. ICC is particularly useful when combined with algorithms that assume that each class has a unimodal Gaussian distribution (e.g., Linear Discriminant Analysis (LDA), quadratic classifiers), an assumption that is not always true in many real-world situations. ICC can help partition non-Gaussian, multimodal distributions to overcome such a problem. In this sense, ICC works as a preprocessor. Experiments with our ICC algorithm on synthetic data sets and real-world data sets indicated that it can significantly improve the performance of LDA and quadratic classifiers. We expect our approach to be applicable to a broader class of pattern recognition problems where class-conditional densities are significantly non-Gaussian or multi-modal. © 2013 Elsevier Ltd. All rights reserved.

  14. Algebraic Structures using Natural Class of Intervals

    CERN Document Server

    Kandasamy, W B Vasantha

    2011-01-01

    This book has eleven chapters. Chapter one describes all types of natural class of intervals and the arithmetic operations on them. Chapter two introduces the semigroup of natural class of intervals using R or Zn and study the properties associated with them. Chapter three studies the notion of rings constructed using the natural class of intervals. Matrix theory using the special class of intervals is analyzed in chapter four of this book. Chapter five deals with polynomials using interval coefficients. New types of rings of natural intervals are introduced and studied in chapter six. The notion of vector space using natural class of intervals is built in chapter seven. In chapter eight fuzzy natural class of intervals are introduced and algebraic structures on them is built and described. Algebraic structures using natural class of neutrosophic intervals are developed in chapter nine.Chapter ten suggests some possible applications. The final chapter proposes over 200 problems of which some are at research l...

  15. First-Class Object Sets

    DEFF Research Database (Denmark)

    Ernst, Erik

    2009-01-01

    Typically, an object is a monolithic entity with a fixed interface.  To increase flexibility in this area, this paper presents first-class object sets as a language construct.  An object set offers an interface which is a disjoint union of the interfaces of its member objects.  It may also be used...... for a special kind of method invocation involving multiple objects in a dynamic lookup process.  With support for feature access and late-bound method calls, object sets are similar to ordinary objects, only more flexible.  Object sets are particularly convenient as a lightweight primitive which may...

  16. GLK-CLASS:SUPERSONIC,SUPERNOVA

    Institute of Scientific and Technical Information of China (English)

    王非; 张陆; 来卡

    2009-01-01

    请翻翻后面,这组GLK-CLASS,我们一张全车图片未拍。欣赏它,一定要看特写镜头。我向来抵制电视剧,美剧概莫能外,所以对Sex and The City欠缺最起码的了解。去年GLK-CLASS最初公开露面,就在SATC的片场,一度使我暗暗心痛。这牵连,使我那时对GLK-CLASS也缺乏好感,只觉得这Mercedes-Benz的超级新星,怎么长相那么奇怪。

  17. The theories on inequality: class theory

    Directory of Open Access Journals (Sweden)

    Ali Arslan

    2006-11-01

    Full Text Available This stduy aims to analyse  class theory and its major expansions. In addition, the problems and dilemmas of class theory are discussed. Social inequality, either socially or economically, is one of the most common features of capitalist societies. Some people or some social groups have more money, more prestige, more privilege and more influence on the decision making process.               Two main strategies have been used for analysing and explaining inequalities. The first and most popular strategy is “class theory” which stresses ownership and control to explain class differentiation. It concentrates on the inequalities based mainly on the ownership or non-ownership of economic resources. Class theory was fathered by Karl Marx and especially developed by Marxist writers. Class analysts focus on identification of classes as the major social forces of society. There are two main schools of thought in class theory with their variations within each school: a Marxist Class Theory, b Weberian Class Theory  If the Marxist class analysis and Weberian class analysis are examined it will be seen that, two approaches are incompatible and it is impossible to synthesise them. Nevertheless, Hindess sees Weber’s view as the correction of and supplement to Marx’s ideas rather than an alternative. When the ideas of Marx and Weber are compared, it will be clearly seen that both Marx and Weber explain classes in relation to the economy. Nevertheless, while Marx defines classes in terms of the relations of production, Weber defines them in relation to the market. 

  18. Class B0631+519: Last of the Class Lenses

    Energy Technology Data Exchange (ETDEWEB)

    York, Tom; Jackson, N.; Browne, I.W.A.; Koopmans, L.V.E.; McKean, J.P.; Norbury, M.A.; Biggs, A.D.; Blandford, R.D.; de Bruyn, A.G.; Fassnacht, C.D.; Myers, S.T.; Pearson, T.J.; Phillips, P.M.; Readhead, A.C.S.; Rusin, D.; Wilkinson, P.N.; /Jodrell Bank /Kapteyn Astron. Inst., Groningen /UC, Davis /JIVE, Dwingeloo /KIPAC, Menlo Park /NFRA,

    2005-05-31

    We report the discovery of the new gravitational lens system CLASS B0631+519. Imaging with the VLA, MERLIN and the VLBA reveals a doubly-imaged flat-spectrum radio core, a doubly-imaged steep-spectrum radio lobe and possible quadruply-imaged emission from a second lobe. The maximum separation between the lensed images is 1.16 arcsec. High resolution mapping with the VLBA at 5 GHz resolves the most magnified image of the radio core into a number of sub-components spread across approximately 20 mas. No emission from the lensing galaxy or an odd image is detected down to 0.31 mJy (5{sigma}) at 8.4 GHz. Optical and near-infrared imaging with the ACS and NICMOS cameras on the HST show that there are two galaxies along the line of sight to the lensed source, as previously discovered by optical spectroscopy. We find that the foreground galaxy at z=0.0896 is a small irregular, and that the other, at z=0.6196 is a massive elliptical which appears to contribute the majority of the lensing effect. The host galaxy of the lensed source is detected in the HST near-infrared imaging as a set of arcs, which form a nearly complete Einstein ring. Mass modeling using non-parametric techniques can reproduce the near-infrared observations and indicates that the small irregular galaxy has a (localized) effect on the flux density distribution in the Einstein ring at the 5-10% level.

  19. Revisiting Parametric Types and Virtual Classes

    DEFF Research Database (Denmark)

    Madsen, Anders Bach; Ernst, Erik

    2010-01-01

    structural manner, because virtual classes are closely tied to nominal typing. This paper adds new insight about the dichotomy between these two approaches; it illustrates how virtual constraints and type refinements, as recently introduced in gbeta and Scala, enable structural treatment of virtual types......This paper presents a conceptually oriented updated view on the relationship between parametric types and virtual classes. The traditional view is that parametric types excel at structurally oriented composition and decomposition, and virtual classes excel at specifying mutually recursive families...... of classes whose relationships are preserved in derived families. Conversely, while class families can be specified using a large number of F-bounded type parameters, this approach is complex and fragile; and it is difficult to use traditional virtual classes to specify object composition in a...

  20. New class of neutron detectors

    Energy Technology Data Exchange (ETDEWEB)

    Czirr, J.B.

    1997-09-01

    An optimized neutron scattering instrument design must include all significant components, including the detector. For example, useful beam intensity is limited by detector dead time; detector pixel size determines the optimum beam diameter, sample size, and sample to detector distance; and detector efficiency vs. wavelength determines the available energy range. As an example of the next generation of detectors that could affect overall instrumentation design, we will describe a new scintillator material that is potentially superior to currently available scintillators. We have grown and tested several small, single crystal scintillators based upon the general class of cerium-activated lithium lanthanide borates. The outstanding characteristic of these materials is the high scintillation efficiency-as much as five times that of Li-glass scintillators. This increase in light output permits the practical use of the exothermic B (n, alpha) reaction for low energy neutron detection. This reaction provides a four-fold increase in capture cross section relative to the Li (n, alpha) reaction, and the intriguing possibility of demanding a charged-particle/gamma ray coincidence to reduce background detection rates. These new materials will be useful in the thermal and epithermal energy ran at reactors and pulsed neutron sources.

  1. MFV-Class:a multi-faceted visualization tool of object classes

    Institute of Scientific and Technical Information of China (English)

    张志猛; 潘云鹤; 庄越挺

    2004-01-01

    Classes are key software components in an object-oriented software system. In many industrial OO software systems,there are some classes that have complicated structure and relationships. So in the processes of software maintenance,testing,software reengineering,software reuse and software restructure,it is a challenge for software engineers to understand these classes thoroughly. This paper proposes a class comprehension model based on constructivist learning theory,and implements a software visualization tool(MFV-Class)to help in the comprehension of a class. The tool provides multiple views of class to uncover manifold facets of class contents. It enables visualizing three object-oriented metrics of classes to help users focus on the understanding process. A case study was conducted to evaluate our approach and the toolkit.

  2. Evaluation of arch width among Class I normal occlusion, Class II Division 1, Class II Division 2, and Class III malocclusion in Indian population

    OpenAIRE

    Dolly Patel; Falguni Mehta; Nimesh Patel; Nishit Mehta; Ipist Trivedi; Apexa Mehta

    2015-01-01

    Objective: To test the hypothesis that there is no difference between Class I (CI) normal occlusion, Class II division 1 (CIId1) and CII division 2 (CIId2), and Class III (CIII) malocclusion with respect to arch widths, width of the maxillary and mandibular arches, gender dimorphism within groups, and gender comparisons. Materials and Methods: Samples of 40 CI subjects, 40 CIId1 subjects, 40 CIId2 subjects, and 34 CIII subjects were studied. All subjects were Indians with no history of or...

  3. Reaction to New Security Threat Class

    OpenAIRE

    Elovici, Yuval; Rokach, Lior

    2014-01-01

    Each new identified security threat class triggers new research and development efforts by the scientific and professional communities. In this study, we investigate the rate at which the scientific and professional communities react to new identified threat classes as it is reflected in the number of patents, scientific articles and professional publications over a long period of time. The following threat classes were studied: Phishing; SQL Injection; BotNet; Distributed Denial of Service; ...

  4. Variational Lie derivative and cohomology classes

    Science.gov (United States)

    Palese, Marcella; Winterroth, Ekkehart

    2011-07-01

    We relate cohomology defined by a system of local Lagrangian with the cohomology class of the system of local variational Lie derivative, which is in turn a local variational problem; we show that the latter cohomology class is zero, since the variational Lie derivative `trivializes' cohomology classes defined by variational forms. As a consequence, conservation laws associated with symmetries of the second variational derivative of a local variational problem are globally defined.

  5. Consumer behavior of the middle class

    OpenAIRE

    Kostyuk, Oleh

    2013-01-01

    The topic of my bachelor thesis is consumer behavior and social stratification. The thesis specifically focuses on the middle class. The aim is to find the differences in the consumer behavior of the middle class and to compare it with other classes. The theoretical part is divided into two parts . The first one is dedicated to consumer behavior, models of explication of this behavior and consumer dispositions. The second one addresses to social stratification, segmentation of the market. The...

  6. Asymptotic study of subcritical graph classes

    CERN Document Server

    Drmota, Michael; Kang, Mihyun; Kraus, Veronika; Rué, Juanjo

    2010-01-01

    We present a unified general method for the asymptotic study of graphs from the so-called "subcritical"$ $ graph classes, which include the classes of cacti graphs, outerplanar graphs, and series-parallel graphs. This general method works both in the labelled and unlabelled framework. The main results concern the asymptotic enumeration and the limit laws of properties of random graphs chosen from subcritical classes. We show that the number $g_n/n!$ (resp. $g_n$) of labelled (resp. unlabelled) graphs on $n$ vertices from a subcritical graph class ${\\cG}=\\cup_n {\\cG_n}$ satisfies asymptotically the universal behaviour

  7. Long-term effects of class size

    OpenAIRE

    Fredriksson, Peter; Öckert, Björn; Oosterbeek, Hessel

    2012-01-01

    This paper evaluates the long-term effects of class size in primary school. We use rich administrative data from Sweden and exploit variation in class size created by a maximum class size rule. Smaller classes in the last three years of primary school (age 10 to 13) are not only beneficial for cognitive test scores at age 13 but also for non-cognitive scores at that age, for cognitive test scores at ages 16 and 18, and for completed education and wages at age 27 to 42. The estimated effect on...

  8. Long-Term Effects of Class Size

    OpenAIRE

    Fredriksson, Peter; Öckert, Björn; Oosterbeek, Hessel

    2011-01-01

    This paper evaluates the long-term effects of class size in primary school. We use rich administrative data from Sweden and exploit variation in class size created by a maximum class size rule. Smaller classes in the last three years of primary school (age 10 to 13) are not only beneficial for cognitive test scores at age 13 but also for non-cognitive scores at that age, for cognitive test scores at ages 16 and 18, and for completed education and wages at age 27 to 42. The estimated effect on...

  9. Long-term effects of class size

    OpenAIRE

    Fredriksson, Peter; Öckert, Björn; Oosterbeek, Hessel

    2011-01-01

    This paper evaluates the long-term effects of class size in primary school. We use rich administrative data from Sweden and exploit variation in class size created by a maximum class size rule. Smaller classes in the last three years of primary school (age 10 to 13) are not only beneficial for cognitive test scores at age 13 but also for non-cognitive scores at that age, for cognitive test scores at ages 16 and 18, and for completed education and wages at age 27 to 42. The estimated effect on...

  10. Class diagram based evaluation of software performance

    Science.gov (United States)

    Pham, Huong V.; Nguyen, Binh N.

    2013-03-01

    The evaluation of software performance in the early stages of the software life cycle is important and it has been widely studied. In the software model specification, class diagram is the important object-oriented software specification model. The measures based on a class diagram have been widely studied to evaluate quality of software such as complexity, maintainability, reuse capability, etc. However the software performance evaluation based on Class model has not been widely studied, especially for object-oriented design of embedded software. Therefore, in this paper we propose a new approach to directly evaluate the software performance based on class diagrams. From a class diagram, we determine the parameters which are used to evaluate and build formula of the measures such as Size of Class Variables, Size of Class Methods, Size of Instance Variables, Size of Instance Methods, etc. Then, we do analysis of the dependence of performance on these measures and build the performance evaluation function from class diagram. Thereby we can choose the best class diagram based on this evaluation function.

  11. Presence of Third Molar Germs in Orthodontic Patients with Class II/2 and Class III Malocclusions

    OpenAIRE

    Maričić, Barbara Mady; Legović, Mario; Šlaj, Martina; Lapter Varga, Marina; Žuvić Butorac, Marta; Kapović, Miljenko

    2009-01-01

    The aim of this study was to determine the presence of third molar germs in patients with Class II/2 and Class III malocclusions. The study comprised 146 examinees from Zagreb and Istria. Examinees with Class II/2 malocclusions amounted to 77 and those with Class III 69. With regard to development of dentition the examinees were divided into two groups: Group I subjects with early mixed dentition (23 subjects with Class II/2 and 21 subjects with Class III), and Group II subjects with late mix...

  12. Toward a Longitudinal, Multi-Dimensional Class Model

    OpenAIRE

    James C. Witte

    2001-01-01

    A longitudinal analytical framework, one that sees class as a process over time and not a fixed attribute, is proposed as a means to redirect class analysis and revive a theoretical debate that has gone stale. Class analysis implies an inherently dynamic perspective. However, quantitative studies of class that go beyond static analyses of cross-sections are rare. Three dimensions of class may be identified in previous work on the effects of class: 1) class as market situation, 2) class as soc...

  13. A Class of Binomial Permutation Polynomials

    OpenAIRE

    Tu, Ziran; Zeng, Xiangyong; Hu, Lei; Li, Chunlei

    2013-01-01

    In this note, a criterion for a class of binomials to be permutation polynomials is proposed. As a consequence, many classes of binomial permutation polynomials and monomial complete permutation polynomials are obtained. The exponents in these monomials are of Niho type.

  14. Software Training Classes Now Open | Poster

    Science.gov (United States)

    By Nancy Parrish, Staff Writer                                            Data Management Services, Inc. (DMS), has announced the opening of its spring session of software training classes, available to all employees at NCI at Frederick. Classes begin on March 31 and run through June 30.

  15. Higher Education and Class: Production or Reproduction?

    Science.gov (United States)

    Sotiris, Panagiotis

    2013-01-01

    This article deals with questions relating to the role of education and especially Higher Education in the reproduction of class division in society. Social classes and how they are formed and reproduced has always been one of the greatest challenges for Marxism and social theory in general. The questions regarding the role of education, and…

  16. A CLASS OF IPPS SAMPLING SCHEMES

    Directory of Open Access Journals (Sweden)

    L.N. Sahoo1# ; S.C. Senapati**2; A.K. Mangaraj***

    2010-09-01

    Full Text Available This paper introduces a general class of Inclusion Probability Proportional to Size (IPPS sampling schemes for selecting two units from a finite population. All IPPS sampling schemes, identified as particular members of this class, possess some desirable properties with regard to the inclusion probabilities, and provide unbiased and non-negative variance estimators under Horvitz-Thomson (HT model.

  17. Social Class on Campus: Theories and Manifestations

    Science.gov (United States)

    Barratt, Will

    2011-01-01

    This is at once a playful text with a serious purpose: to provide the reader with the theoretical lenses to analyze the dynamics of social class. It will appeal to students, and indeed anyone interested in how class mediates relationships in higher education, both because of its engaging tone, and because it uses the college campus as a microcosm…

  18. Social Class and Education: Global Perspectives

    Science.gov (United States)

    Weis, Lois, Ed.; Dolby, Nadine, Ed.

    2012-01-01

    "Social Class and Education: Global Perspectives" is the first empirically grounded volume to explore the intersections of class, social structure, opportunity, and education on a truly global scale. Fifteen essays from contributors representing the US, Europe, China, Latin America and other regions offer an unparralleled examination of how social…

  19. Price Responsiveness of Wheat Class Demands

    OpenAIRE

    Gallagher, Paul; Wilson, William W.; Riepe, Jean

    1988-01-01

    This paper identifies the price responsiveness and preferences for wheat classes using a "Case" Function specification. Results indicate there have been numerous changes in market shares of wheat classes from the different exporters in specific markets. In general, quality differentials are important in some international markets, whereas others are very price responsive.

  20. Using Mobile Phone Technology in EFL Classes

    Science.gov (United States)

    Sad, Süleyman Nihat

    2008-01-01

    Teachers of English as a foreign language (EFL) who want to develop successful lessons face numerous challenges, including large class sizes and inadequate instructional materials and technological support. Another problem is unmotivated students who refuse to participate in class activities. According to Harmer (2007), uncooperative and…

  1. World-Class Higher Education (for Whom?)

    Science.gov (United States)

    Robertson, Susan L.

    2012-01-01

    The slogan "world-class education" is ubiquitous in education circles. This essay looks closely at who is advancing this idea, why, and where, and the kind of work it is asked to do. Though instruments for determining the world-class status of education institutions were first launched in the 1980s, they have grown exponentially in the past…

  2. Intercultural and Media Education on Art Classes

    Science.gov (United States)

    Borges, Maria José; Chaves, Anabela; Costa, Manuela; Pereira, Emília Sá

    2009-01-01

    Visual art, music and literature, are part of the culture. Thus Art shows the interactions between different cultures. The aim of the article is to present some activities to include intercultural issues in Art and Mother Language classes. Art classes also give the opportunity to do Media Education.

  3. 2m class telescope project at Lijiang

    Science.gov (United States)

    Chen, Dong; Wang, Jian-Cheng; Xu, Jun; Zhang, Bai-Rong; Luo, Guo-Quan; Liu, Zhong; Tan, Hui-Song

    Supported by the ministry of science and technology, government of Yunnan Province and Chinese Academy of Sciences, a 2m class telescope project was granted. In this paper, we will first review the site, Gaomeigu, briefly, then give the details of 2m class telescope project, and finally discuss the future plans of this new telescope.

  4. Gender, Class and Rurality: Australian Case Studies

    Science.gov (United States)

    Bryant, Lia; Pini, Barbara

    2009-01-01

    The interrelationship between gender and class in rural spaces has received little attention. While rural scholars have focused on the implications for class from processes of gentrification and agricultural and rural restructuring, these analyses have remained largely ungendered. Similarly, feminist rural studies have rarely explored subjectivity…

  5. The YouTube Makeup Class

    Science.gov (United States)

    Haase, David G.

    2009-01-01

    When a college instructor goes out of town and must miss a lecture, the standard options are to cancel the class meeting or to enlist a colleague to fill in. In the former case a teaching opportunity is lost; in the latter the substitute may not lead the class in the same way as the instructor. Some students routinely skip lectures by a guest…

  6. Python Classes for Numerical Solution of PDE's

    OpenAIRE

    Asif Mushtaq; Trond Kvamsdal; Kare Olaussen

    2015-01-01

    We announce some Python classes for numerical solution of partial differential equations, or boundary value problems of ordinary differential equations. These classes are built on routines in \\texttt{numpy} and \\texttt{scipy.sparse.linalg} (or \\texttt{scipy.linalg} for smaller problems).

  7. Listening and Learning in a Master Class

    Science.gov (United States)

    Hanken, Ingrid Maria

    2015-01-01

    Most higher education institutions offering programmes in music performance organise master classes for their students. It is commonly agreed that master classes offer valuable learning opportunities for the students performing, but what do they offer for students in the audience? In this article, theories of learning by observation as well as…

  8. Near-Ring Radicals and Class Pairs

    Institute of Scientific and Technical Information of China (English)

    L.Godloza; N.J.Groenewald; W.A.Olivier

    2005-01-01

    For near-ring ideal mappings p1 and p2, we investigate radical theoretical properties of and the relationship among the class pairs (p1: p2), (Sp2: Sp1) and (Rp2:Rp1). Conditions on p1 and p2 are given for a general class pair to form a radical class of various types. These types include the Plotkin and KA-radical varieties. A number of examples are shown to motivate the suitability of the theory of Hoehnke-radicals over KA-radicals when radical pairs of near-rings are studied. In particular, it is shown that (pc: P3) forms a KA-radical class, where Pc denotes the class of completely prime nearrings and P3 the class of 3-prime near-rings. This gives another near-ring generalization of the 2-primal ring concept. The theory of radical pairs are also used to show that in general the class of 3-semiprime near-rings is not the semisimple class of the 3-prime radical.

  9. New UDC class 004 for computer science

    OpenAIRE

    Butigan-Vučaj, Tamara

    2002-01-01

    In this paper, the new Class 004 for Computer Science, in the system of Universal Decimal Classification, has been described, along with its practical application through examples. The Class 004 provides entirely new possibilities for the classification of documents, linked to this domain, and that will probably contribute to the amelioration of the quality of the Information for the Users.

  10. A new Class of Extremal Composites

    DEFF Research Database (Denmark)

    Sigmund, Ole

    2000-01-01

    The paper presents a new class of two-phase isotropic composites with extremal bulk modulus. The new class consists of micro geometrics for which exact solutions can be proven and their bulk moduli are shown to coincide with the Hashin-Shtrikman bounds. The results hold for two and three dimensio...

  11. Individual and Group Credit for Class Participation

    Science.gov (United States)

    Taylor, Cora M.; Galyon, Charles E.; Forbes, Bethany E.; Blondin, Carolyn A.; Williams, Robert L.

    2014-01-01

    This research study focused on the use of cooperative groups to facilitate class-wide participation, especially for initially low participants. Undergraduates from three sections of a relatively large educational psychology course recorded their class participation in all course units. Four of the five units in each section offered either…

  12. Various chapter styles for the memoir class

    DEFF Research Database (Denmark)

    Madsen, Lars

    2008-01-01

    Document showcasing various chapter title page designs either included in the LaTeX memoir class or is easily manually coded.......Document showcasing various chapter title page designs either included in the LaTeX memoir class or is easily manually coded....

  13. Inclusion relations between classes of hypergeometric functions

    Directory of Open Access Journals (Sweden)

    O. P. Ahuja

    1994-01-01

    Full Text Available The use of hypergeometric functions in univalent function theory received special attention after the surprising application of such functions by de Branges in the proof of the 70-year old Bieberbach Conjecture. In this paper we consider certain classes of analytic functions and examine the distortion and containment properties of generalized hypergeometric functions under some operators in these classes.

  14. So, Where Are We with Class Size?

    Science.gov (United States)

    Johnson, Donald P.

    2001-01-01

    Although class-size reductions cannot guarantee better student performance, the Tennessee and Wisconsin experiences, along with other studies, suggest that successful programs share key characteristics: concentration in the primary schooling years, classes with not more than 20 students, greater benefits for urban minority students, and alignment…

  15. Mutational Analysis of the Streptococcus pneumoniae Bimodular Class A Penicillin-Binding Proteins

    OpenAIRE

    Paik, Johanna; Kern, Iza; Lurz, Rudi; Hakenbeck, Regine

    1999-01-01

    One group of penicillin target enzymes, the class A high-molecular-weight penicillin-binding proteins (PBPs), are bimodular enzymes. In addition to a central penicillin-binding–transpeptidase domain, they contain an N-terminal putative glycosyltransferase domain. Mutations in the genes for each of the three Streptococcus pneumoniae class A PBPs, PBP1a, PBP1b, and PBP2a, were isolated by insertion duplication mutagenesis within the glycosyltransferase domain, documentin...

  16. MATLAB tensor classes for fast algorithm prototyping.

    Energy Technology Data Exchange (ETDEWEB)

    Bader, Brett William; Kolda, Tamara Gibson (Sandia National Laboratories, Livermore, CA)

    2004-10-01

    Tensors (also known as mutidimensional arrays or N-way arrays) are used in a variety of applications ranging from chemometrics to psychometrics. We describe four MATLAB classes for tensor manipulations that can be used for fast algorithm prototyping. The tensor class extends the functionality of MATLAB's multidimensional arrays by supporting additional operations such as tensor multiplication. The tensor as matrix class supports the 'matricization' of a tensor, i.e., the conversion of a tensor to a matrix (and vice versa), a commonly used operation in many algorithms. Two additional classes represent tensors stored in decomposed formats: cp tensor and tucker tensor. We descibe all of these classes and then demonstrate their use by showing how to implement several tensor algorithms that have appeared in the literature.

  17. A new model of social class : findings from the BBC's Great British Class Survey Experiment.

    OpenAIRE

    Savage, Mike; Devine, Fiona; Cunningham, Niall; Taylor, Mark; Li, Yaojun; Hjellbrekke, Johs.; Le Roux, Brigitte; Friedman, Sam; Miles, Andrew

    2013-01-01

    The social scientific analysis of social class is attracting renewed interest given the accentuation of economic and social inequalities throughout the world. The most widely validated measure of social class, the Nuffield class schema, developed in the 1970s, was codified in the UK’s National Statistics Socio-Economic Classification (NS-SEC) and places people in one of seven main classes according to their occupation and employment status. This principally distinguishes between people workin...

  18. Student attitudes about class absences, class attendance, and requiring attendance at Virginia Tech

    OpenAIRE

    Hileman, Annmarie Long

    1992-01-01

    Seventy-nine undergraduate students were interviewed in February, 1992, to determine attitudes about class attendance, class absences, and required attendance. Three hundred undergraduates were selected in a random sample; seventy-nine attended one of the six group interview sessions. The reasons students gave for skipping classes included being lazy or tired, dislike of the professor, material for the class was seen as unimportant, bad or nice weather, early mornin...

  19. The Continuing Story of Class IIa Bacteriocins

    Science.gov (United States)

    Drider, Djamel; Fimland, Gunnar; Héchard, Yann; McMullen, Lynn M.; Prévost, Hervé

    2006-01-01

    Many bacteria produce antimicrobial peptides, which are also referred to as peptide bacteriocins. The class IIa bacteriocins, often designated pediocin-like bacteriocins, constitute the most dominant group of antimicrobial peptides produced by lactic acid bacteria. The bacteriocins that belong to this class are structurally related and kill target cells by membrane permeabilization. Despite their structural similarity, class IIa bacteriocins display different target cell specificities. In the search for new antibiotic substances, the class IIa bacteriocins have been identified as promising new candidates and have thus received much attention. They kill some pathogenic bacteria (e.g., Listeria) with high efficiency, and they constitute a good model system for structure-function analyses of antimicrobial peptides in general. This review focuses on class IIa bacteriocins, especially on their structure, function, mode of action, biosynthesis, bacteriocin immunity, and current food applications. The genetics and biosynthesis of class IIa bacteriocins are well understood. The bacteriocins are ribosomally synthesized with an N-terminal leader sequence, which is cleaved off upon secretion. After externalization, the class IIa bacteriocins attach to potential target cells and, through electrostatic and hydrophobic interactions, subsequently permeabilize the cell membrane of sensitive cells. Recent observations suggest that a chiral interaction and possibly the presence of a mannose permease protein on the target cell surface are required for a bacteria to be sensitive to class IIa bacteriocins. There is also substantial evidence that the C-terminal half penetrates into the target cell membrane, and it plays an important role in determining the target cell specificity of these bacteriocins. Immunity proteins protect the bacteriocin producer from the bacteriocin it secretes. The three-dimensional structures of two class IIa immunity proteins have been determined, and it has

  20. Social Class (In)Visibility and the Professional Experiences of Middle-Class Novice Teachers

    Science.gov (United States)

    Hall, David; Jones, Lisa

    2013-01-01

    This article focuses upon the classed and early professional experiences of middle-class novice teachers in England experiencing and contemplating working in schools serving socio-economically disadvantaged communities. Through an examination of the visibility and invisibility of social class in education set within an increasingly unequal and…

  1. Self-Education, Class and Gender in Edwardian Britain: Women in Lower Middle Class Families

    Science.gov (United States)

    Sutherland, Gillian

    2015-01-01

    Once societies embarked on programmes of mass education home schooling became essentially a middle-class project and remains so. This paper looks at the educational experiences of some lower middle class women at the turn of the nineteenth and twentieth centuries for whom the resources of the middle-class home were simply not available. It…

  2. On Students' Self-Evaluation and Class Performance-An Empirical Study in College English Class

    Institute of Scientific and Technical Information of China (English)

    朱周贤

    2014-01-01

    This paper aims to demonstrate whether students' self-evaluations influence their class performance. A questionnaire is designed and data is collected from 30 sophomore students in English class. The data analysis shows that students who have posi-tive self-evaluation perform better and get higher class performance scores than students who have negative self-evaluation.

  3. Evolution of major histocompatibility complex class I and class II genes in the brown bear

    Directory of Open Access Journals (Sweden)

    Kuduk Katarzyna

    2012-10-01

    Full Text Available Abstract Background Major histocompatibility complex (MHC proteins constitute an essential component of the vertebrate immune response, and are coded by the most polymorphic of the vertebrate genes. Here, we investigated sequence variation and evolution of MHC class I and class II DRB, DQA and DQB genes in the brown bear Ursus arctos to characterise the level of polymorphism, estimate the strength of positive selection acting on them, and assess the extent of gene orthology and trans-species polymorphism in Ursidae. Results We found 37 MHC class I, 16 MHC class II DRB, four DQB and two DQA alleles. We confirmed the expression of several loci: three MHC class I, two DRB, two DQB and one DQA. MHC class I also contained two clusters of non-expressed sequences. MHC class I and DRB allele frequencies differed between northern and southern populations of the Scandinavian brown bear. The rate of nonsynonymous substitutions (dN exceeded the rate of synonymous substitutions (dS at putative antigen binding sites of DRB and DQB loci and, marginally significantly, at MHC class I loci. Models of codon evolution supported positive selection at DRB and MHC class I loci. Both MHC class I and MHC class II sequences showed orthology to gene clusters found in the giant panda Ailuropoda melanoleuca. Conclusions Historical positive selection has acted on MHC class I, class II DRB and DQB, but not on the DQA locus. The signal of historical positive selection on the DRB locus was particularly strong, which may be a general feature of caniforms. The presence of MHC class I pseudogenes may indicate faster gene turnover in this class through the birth-and-death process. South–north population structure at MHC loci probably reflects origin of the populations from separate glacial refugia.

  4. Multiple states of the Tyr318Leu mutant of dihydroorotate dehydrogenase revealed by single molecule kinetics

    DEFF Research Database (Denmark)

    Shi, J.; Palfey, B.A.; Dertouzos, J.;

    2004-01-01

    single enzyme molecules through the characteristic on-off fluorescence signal, which corresponds to flavin mononucleotide (FMN) interconverting between the oxidized and reduced states during turnover. Our single-molecule data provide evidence of a distinct static heterogeneity in the enzymatic activity......, with some molecules going through the on-off cycles 5-fold faster than others, however, there is no detectable dynamic disorder in DHOD turnover. When 0.1% reduced Triton X-100, a detergent that more closely simulates the natural membrane environment, is added, our data suggest the degree of static...... molecular heterogeneity is reduced. The observation of static heterogeneity suggests that the enzyme, which associates with the membrane in vivo, is present in distinct conformations that result in different catalytic efficiencies. The alternate conformations are most likely the result of the loss of van...

  5. Postura de cabeça nas deformidades dentofaciais classe II e classe III Head posture in the presence of class II and class III dentofacial deformities

    Directory of Open Access Journals (Sweden)

    Marcela Ralin de Carvalho Deda

    2012-04-01

    Full Text Available OBJETIVO: este estudo investiga se existe diferença entre grupos com diferentes deformidades dentofaciais (padrão classe II e classe III e o grupo sem a deformidade em relação à postura de cabeça. MÉTODO: participaram deste estudo, voluntariamente, 25 pacientes (entre 16 e 40 anos. Dez pacientes com diagnóstico de deformidade dentofacial classe II e 15 pacientes com o diagnóstico de classe III esquelética e 15 voluntários sadios, com equivalência em sexo e idade ao grupo de deformidade, formando o grupo controle. Primeiramente foi realizada a inspeção da postura de cabeça. Logo em seguida foi realizada a avaliação postural de cabeça por meio da fotografia postural (fotogrametria. RESULTADOS: não houve diferença significante (p>0,05 entre os grupos em relação à avaliação postural utilizando-se a fotogrametria. Já em relação à avaliação postural pela inspeção clínica, observou-se uma postura anterior de cabeça nos indivíduos com a deformidade dentofacial padrão classe II, comparados ao padrão classe III (p = 0,001 e ao grupo controle (p = 0,001. Foi visto também que o grupo deformidade classe II apresentou um percentual inferior de indivíduos com posição neutra de cabeça comparado ao grupo deformidade classe III (p = 0,008 e ao grupo controle (p = 0,001. CONCLUSÃO: indivíduos com deformidade dentofacial classe II podem apresentar uma anteriorização de cabeça. Não há influência da deformidade no aumento ou na redução do ângulo cabeça-pescoço, analisado por meio da fotogrametria.PURPOSE: this study investigates whether there is a difference in head posture between groups with different dentofacial deformities (class II and class III and a group with no deformity. METHOD: 25 volunteers aged from 16 to 40 year old took part in the study. Ten patients had a diagnosis of class II dentofacial deformity, 15 had a diagnosis of class III skeletal deformity, and 15 healthy volunteers matched for sex and

  6. Automatic Identification Systems the Effects of Class B on the Use of Class A Systems

    Science.gov (United States)

    Norris, Andy

    2006-05-01

    The standards for CSTDMA Class B AIS will shortly be published by the International Electrotechnical Commission and equipment will become available during 2006. The perceived benefits that Class B brings to leisure craft users and its relatively low cost will make it attractive in the market place. A rapid take-up of Class B use can therefore be expected. This paper considers the impact that increased use of Class B will have on users of Class A AIS that are compulsorily fitted to larger vessels to meet the requirements of the International Maritime Organization Safety of Life at Sea convention. The CSTDMA Class B system has been designed to prevent overloading of the AIS VHF data link. This is briefly reviewed but there are a number of other aspects that need to be considered. These include: the increased garbling of Class B messages compared to those of Class A; the problems accruing from the low update rate of Class B information; the increase in display information that will need to be managed; and the possible increase in inappropriate manoeuvres of leisure craft caused by misplaced reliance on AIS. As a result of the investigation the paper highlights the fact that Class B users must not assume that their own presence, in the form of Class B transmissions, will be particularly visible on the bridge of many SOLAS vessels. This will continue to be the case for many years into the future, until such vessels are mandated to carry radar with AIS target overlay capability.

  7. Hochschild homology and microlocal Euler classes

    CERN Document Server

    Kashiwara, Masaki

    2012-01-01

    We define the notion of a Hochschild kernel on a manifold M. Roughly speaking, it is a sheaf on M x M for which the formalism of Hochschild homology applies. We associate a microlocal Euler class to such a kernel, a cohomology class with values in the relative dualizing complex of the cotangent bundle over M and we prove that this class is functorial with respect to the composition of kernels. This generalizes, unifies and simplifies various results of (relative) index theorems for constructible sheaves, D-modules and elliptic pairs.

  8. Teaching or Tyranny: Class and Course Guides

    OpenAIRE

    Noe, Nancy W

    2016-01-01

    The adoption of LibGuides by numerous Libraries has given rise to the creation of a multitude of class or course guides within the system. Librarians have become enamored of such pages and spend hours developing pages for a number of classes. Many of these guides are then used in actual library instruction, or embedded into learning and course management systems as substitutes for face-to-face sessions. Upon examination, however, the vast majority of these class and course guides simply repli...

  9. Class IIa Bacteriocins: Current Knowledge and Perspectives

    Science.gov (United States)

    Belguesmia, Yanath; Naghmouchi, Karim; Chihib, Nour-Eddine; Drider, Djamel

    Lactic acid bacteria (LAB) are known to produce antibacterial peptides and small proteins called bacteriocins, which enable them to compete against other bacteria in the environment. Bacteriocins fall structurally and chemically into three different classes, I, II, and III. Bacteriocins are ribosomally synthesized peptides with antagonism against closely related bacteria. This late observation has evolved because bacteriocins active against Gram-negative bacteria have recently been reported. Members of class IIa bacteriocins, referred to as pediocin-like bacteriocins, are among the most studied bacteriocins. This chapter is aimed at providing an updated review on the biology of class IIa bacteriocins.

  10. Class, race, and social mobility in Brazil

    Directory of Open Access Journals (Sweden)

    Carlos Antonio Costa Ribeiro

    2007-01-01

    Full Text Available This article analyzes the differences in inter-generational social mobility and schooling between white, brown, and black men in Brazil. The main objective is to analyze inequality of opportunities for mobility and educational transitions. The results indicate that for individuals from lower social origins, inequality of opportunities is significantly marked by racial differences, and that for persons originating in the upper classes, racial inequality influences the odds of social mobility. The results suggest that theories of stratification by race and class in Brazil should be rethought, taking into account the observed interactions between race and class.

  11. Universality Class of Fluctuating Pulled Fronts

    International Nuclear Information System (INIS)

    It has recently been proposed that fluctuating 'pulled' fronts propagating into an unstable state should not be in the standard Kardar-Parisi-Zhang (KPZ) universality class for rough interface growth. We introduce an effective field equation for this class of problems, and show on the basis of it that noisy pulled fronts in d+1 bulk dimensions should be in the universality class of the ((d+1)+1) D KPZ equation rather than of the (d+1)D KPZ equation. Our scenario ties together a number of heretofore unexplained observations in the literature, and is supported by previous numerical results

  12. The State of the Australian Middle Class

    Directory of Open Access Journals (Sweden)

    Clive Hamilton

    2008-09-01

    Full Text Available There is a widespread view that the middle class in Australia is doing it tough, that they arefinding it increasingly difficult to maintain a decent standard of living and are suffering frommortgage stress. Indeed, some media reports have announced the end of the middle classdream.This paper tests a number of these popular views against the statistical data. It asks whetherthe typical Australian family can be said to be struggling? Are mortgages creating severeproblems for middle-class families? Is the middle class shrinking? Are families copingfinancially only because wives are going out to work?

  13. Class, Mothering and the Values of Food

    DEFF Research Database (Denmark)

    Aamann, Iben Charlotte

    2015-01-01

    The data analysed in this empirical paper stems from ethnographic fieldwork among new school parents at three Danish primary schools. I draw on empirically grounded theories on the cultural and subjective dimensions of class, inspired by the “English School” of poststructuralist informed, feminist...... scholars, to explore how class matters. Using the values ascribed to food at social arrangements as a lens, I explore different ways of doing class and mothering: through the exchange value of the food, through its use value and through its healthiness. I conclude by arguing that food studies hold a huge...

  14. Aeroflex Technology as Class-Y Demonstrator

    Science.gov (United States)

    Suh, Jong-ook; Agarwal, Shri; Popelar, Scott

    2014-01-01

    Modern space field programmable gate array (FPGA) devices with increased functional density and operational frequency, such as Xilinx Virtex 4 (V4) and S (V5), are packaged in non-hermetic ceramic flip chip forms. These next generation space parts were not qualified to the MIL-PRF-38535 Qualified Manufacturer Listing (QML) class-V when they were released because class-V was only intended for hermetic parts. In order to bring Xilinx V5 type packages into the QML system, it was suggested that class-Y be set up as a new category. From 2010 through 2014, a JEDEC G12 task group developed screening and qualification requirements for Class-Y products. The Document Standardization Division of the Defense Logistics Agency (DLA) has completed an engineering practice study. In parallel with the class-Y efforts, the NASA Electronic Parts and Packaging (NEPP) program has funded JPL to study potential reliability issues of the class-Y products. The major hurdle of this task was the absence of adequate research samples. Figure 1-1 shows schematic diagrams of typical structures of class-Y type products. Typically, class-Y products are either in ceramic flip chip column grid array (CGA) or land grid array (LGA) form. In class-Y packages, underfill and heat spread adhesive materials are directly exposed to the spacecraft environment due to their non-hermeticity. One of the concerns originally raised was that the underfill material could degrade due to the spacecraft environment and negatively impact the reliability of the package. In order to study such issues, it was necessary to use ceramic daisy chain flip chip package samples so that continuity of flip chip solder bumps could be monitored during the reliability tests. However, none of the commercially available class-Y daisy chain parts had electrical connections through flip chip solder bumps; only solder columns were daisy chained, which made it impossible to test continuity of flip chip solder bumps without using extremely

  15. Three Ways to Improve Listening Classes

    Institute of Scientific and Technical Information of China (English)

    邓林竹

    2014-01-01

    Recent years have witnessed numerous studies on how to improve learners’listening comprehension and how to ef-fectively teach listening classes. Despite these efforts, some problems still exist in listening teaching methods in China. In the first part of the essay, three issues in listening classes will be identified. Based on these issues, the second part present three correspond-ing methods of incorporating communicative-based activities, videos and checklists into teaching to improve listening classes. Each method will be justified by relevant theories and literature. A conclusion will be made in the end.

  16. Meta-universality classes at criticality

    CERN Document Server

    Blythe, Duncan A J

    2015-01-01

    Inferring the presence of critical dynamics from continuous measure- ments is a challenging problem. We solve this problem by showing that continuous narrowband dynamics from a critical system exhibit qualita- tively differing behaviors which depend on the universality class; we term each region of critical avalanche parameters which generates qualitatively constant behavior a meta-universality class. This theoretical observation allows us to infer membership of a given meta-universality class and thus yields a robust test for criticality. We validate these theoretical predic- tions in simulations and provide unequivocal evidence for criticality in the human brain on the basis electrophysiological recordings.

  17. Class and ideological orientations revisited: an exploration of class-based mechanisms.

    Science.gov (United States)

    Bengtsson, Mattias; Berglund, Tomas; Oskarson, Maria

    2013-12-01

    Studies of the relationship between class position and political outlooks still only have a limited understanding of the class-related mechanisms that matter for ideological orientations. This article presents a comprehensive analysis of the mechanisms that link class position and left/right and authoritarian/libertarian orientations. Besides main factors such as income, career prospects, job security, education, class origin and class identification, the significance of work-related factors such as work autonomy, working in a team, a physically demanding job and a mentally demanding job is studied. The findings are based on a survey specifically designed for this purpose and collected in Sweden in 2008/2009. A great deal of the association between class position and left/right orientations is explained by socio-economic conditions; different classes sympathize with policies that will benefit them economically. Another important factor is class identification. Work-related factors also have relevance, but the effect of class position on left/right orientations works mainly through the remuneration system. Class position is also related to authoritarian/libertarian orientations. However, this relationship is less explained by socio-economic position per se, but is rather an effect of the educational system and its allocation of the workforce into different class positions. It also turns out that work-related factors do not explain the class effects; however, a physically demanding job shows a unique effect. Overall, our findings suggest that besides factors such as class position, income, education and class identification, we need to consider work-related aspects to derive a more complete understanding of the distribution of ideological orientations in Western societies. PMID:24320072

  18. Combination Classes and "Hora de comunicacion."

    Science.gov (United States)

    Eldredge, Dee L.

    1989-01-01

    Ways to combine small classes of higher education students studying Spanish at various levels are described, including judicious use of language laboratories, staggering of the different level groups, and rotation of activities geared toward students' individual proficiency levels. (CB)

  19. Hydrography - Class A Wild Trout Streams - points

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Class A streams are streams that support a population of wild (natural reproduction) trout of sufficient size and abundance to support a long-term and rewarding...

  20. Hydrography - Class A Wild Trout Streams

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Class A streams are streams that support a population of wild (natural reproduction) trout of sufficient size and abundance to support a long-term and rewarding...

  1. Clafer: Unifying Class and Feature Modeling

    DEFF Research Database (Denmark)

    Bąk, Kacper; Diskin, Zinovy; Antkiewicz, Michal;

    2015-01-01

    We present Clafer (class, feature, reference), a class modeling language with first-class support for feature modeling. We designed Clafer as a concise notation for meta-models, feature models, mixtures of meta- and feature models (such as components with options), and models that couple feature...... models and meta-models via constraints (such as mapping feature configurations to component configurations or model templates). Clafer allows arranging models into multiple specialization and extension layers via constraints and inheritance. We identify several key mechanisms allowing a meta-modeling...... language to express feature models concisely. Clafer unifies basic modeling constructs, such as class, association, and property, into a single construct, called clafer. We provide the language with a formal semantics built in a structurally explicit way. The resulting semantics explains the meaning of...

  2. Search for second-class current

    International Nuclear Information System (INIS)

    Preliminary results on the β-γ directional correlation in 20F are presented. A practically model-independent analysis of those results and the ones obtained in 20Na is compatible with no second-class current. (author)

  3. Acquired Class D β-Lactamases

    Directory of Open Access Journals (Sweden)

    Nuno T. Antunes

    2014-08-01

    Full Text Available The Class D β-lactamases have emerged as a prominent resistance mechanism against β-lactam antibiotics that previously had efficacy against infections caused by pathogenic bacteria, especially by Acinetobacter baumannii and the Enterobacteriaceae. The phenotypic and structural characteristics of these enzymes correlate to activities that are classified either as a narrow spectrum, an extended spectrum, or a carbapenemase spectrum. We focus on Class D β-lactamases that are carried on plasmids and, thus, present particular clinical concern. Following a historical perspective, the susceptibility and kinetics patterns of the important plasmid-encoded Class D β-lactamases and the mechanisms for mobilization of the chromosomal Class D β-lactamases are discussed.

  4. A new class of variational equation problems

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Applying an analysis method to a group of multivariable equations, a new class of variational equations are proved. This method is more concise and more direct than the others. This result can be applied to some stochastic control models.

  5. On Hereditary Helly classes of graphs

    Directory of Open Access Journals (Sweden)

    Marina Groshaus

    2008-01-01

    Full Text Available In graph theory, the Helly property has been applied to families of sets, such as cliques, disks, bicliques, and neighbourhoods, leading to the classes of clique-Helly, disk-Helly, biclique-Helly, neighbourhood-Helly graphs, respectively. A natural question is to determine for which graphs the corresponding Helly property holds, for every induced subgraph. This leads to the corresponding classes of hereditary clique-Helly, hereditary disk-Helly, hereditary biclique-Helly and hereditary neighbourhood-Helly graphs. In this paper, we describe characterizations in terms of families of forbidden subgraphs, for the classes of hereditary biclique-Helly and hereditary neighbourhood-Helly graphs. We consider both open and closed neighbourhoods. The forbidden subgraphs are all of fixed size, implying polynomial time recognition for these classes.

  6. On characteristic classes and continuous cohomology

    International Nuclear Information System (INIS)

    The paper was presented at the workshop on 'Supersymmetry and its applications', Cambridge, United Kingdom, 1985. Six theorems on characteristic classes and continuous cohomology are described, in connection with the theory of anomalies. (UK)

  7. Motivation-stimulating Strategies in English Classes

    Institute of Scientific and Technical Information of China (English)

    李宁

    2015-01-01

    Motivation plays a very important role in foreign language learning. So it becomes worthwhile to study the teachers’ motivation-stimulating strategies. This article mainly discusses two strategies of stimulating the students’motivation in English classes:environment-providing strategies and goal-oriented strategies. They are hoped to provide some references for English teachers to stimulate the students’learning motivation in their classes.

  8. HUMANISTIC STRATEGIES IN THE EFL SPEAKING CLASS

    OpenAIRE

    Josefa J. Mardijono

    2001-01-01

    This paper focuses on the humanistic strategies woven into the EFL speaking class activities. The speaking class, which the writer used for her study, is the highest level of speaking course offered in the curriculum of the English Department of Petra Christian University, to develop students' English speaking skills, particularly in public speaking. The humanistic strategies are based on the assumption that a "supportive and co-operative group atmosphere" ((Hadfield, 1995, p.15) will enhance...

  9. Full Amalgamation Classes with Intrinsic Transcendentals

    OpenAIRE

    Brody, Justin

    2015-01-01

    We develop some basic results about full amalgamation classes with intrinsic trascendentals. These classes have generics whose models may have finite subsets whose intrinsic closure is not contained in its algebraic closure. We will show that under fairly natural conditions the generic will have an essentially undecidable theory, but we will also exhibit strictly superstable and strictly simple examples. Separating types over a model into those that are intrinsic and those that are extrinsic,...

  10. Water as an Asset Class (Revised Version)

    OpenAIRE

    B. Michael Gilroy; Heike Schreckenberg; Volker Seiler

    2013-01-01

    As correlations of asset returns increased and diversification effects vanished during the financial crisis, the search for new and potentially uncorrelated asset classes gains importance. As a result, several asset classes have been analyzed by academics in order to determine their diversification properties. In this article we take a closer look at water as an asset and its potential diversification benefits. Water as an alternative asset improves a traditional stock and bond portfolio. Tho...

  11. Does social class explain health inequalities?

    OpenAIRE

    Diaz Martinez, Elisa; Dr Richard Breen; Gøsta Esping-Andersen

    2004-01-01

    The main research questions examined in this thesis concern the extent to which social class influence individuals' health, and how and whether individuals' occupation, education and lifestyles mediate between class and health. The conclusions drawn from the analysis of these empirical questions cast further light on the widening health inequalities seen in developed societies in recent decades. In particular, this research suggests that, employment conditions as well as educa...

  12. The economic basis of social class

    OpenAIRE

    John H. Goldthorpe; McKnight, Abigail

    2004-01-01

    In this paper we adopt a theory of class positions based on employment relations to assess what implications individuals¿ class positions have for their economic life. In particular we consider economic security (the risk of unemployment), economic stability (the variability component in earnings) and economic prospects (lifetime earnings profiles). Our findings provide empirical support for the theory itself and little evidence for the currently fashionable claims of the decline, or even dea...

  13. Social Class, Essentialism, and Restorative Policy Decisions

    OpenAIRE

    Kraus, Michael Warren

    2010-01-01

    Social class (socioeconomic status, SES) is a primary determinant of rank in the human social hierarchy, and in the present research I examined lay theories about social class categories and their implications for social policy. Lay theories about social categories (e.g., race, sexual orientation) differ to the extent that they are essential--based on internal, inherent, and stable characteristics--or socially constructed. Theory and research argue that high-ranking individuals in society jus...

  14. Should ESL Classes Never Mention Religion?

    Institute of Scientific and Technical Information of China (English)

    顾炜俊

    2014-01-01

    As religion is an integrated part of human history and culture, an L2 cannot be learnt without some mentioning of it in the language classes. Teaching about religion cannot only help L2 learners learn the L2 itself but other general knowledge such as history, music and arts. However, differences should be made between teaching religion and teaching about religion and some guidelines should be followed if teachers are to teach it in the language classes.

  15. Considerations When Using Videos in Lamaze Classes

    OpenAIRE

    Hotelling, Barbara A.

    2012-01-01

    There are enough worthwhile videos available today so that a Lamaze Certified Childbirth Educator could literally teach an entire class series using only videos and feedback discussion. In this column, the author explores considerations in choosing videos for adult learners in Lamaze birth classes. Some things to consider when using videos should be the adult learner’s attention span, whether the video increases fear of birth or empowers the learner, and if the video is appropriate for the cu...

  16. The Onfp Class in the Magellanic Clouds

    OpenAIRE

    Walborn, Nolan R.; Howarth, Ian D.; Evans, Christopher J.; Crowther, Paul A; Moffat, Anthony F. J.; St-Louis, Nicole; Farina, Cecilia; Bosch, Guillermo L.; Morrell, Nidia I.; Barba, Rodolfo H.; van Loon, Jacco Th.

    2010-01-01

    The Onfp class of rotationally broadened, hot spectra was defined some time ago in the Galaxy, where its membership to date numbers only eight. The principal defining characteristic is a broad, centrally reversed He II $\\lambda$4686 emission profile; other emission and absorption lines are also rotationally broadened. Recent surveys in the Magellanic Clouds (MCs) have brought the class membership there, including some related spectra, to 28. We present a survey of the spectral morphology and ...

  17. Conjugation spaces and equivariant Chern classes

    OpenAIRE

    Pitsch, W.; Scherer, J

    2011-01-01

    Let $\\eta$ be a Real bundle, in the sense of Atiyah, over a space $X$. This is a complex vector bundle together with an involution which is compatible with complex conjugation. We use the fact that $BU$ has a canonical structure of a conjugation space, as defined by Hausmann, Holm, and Puppe, to construct equivariant Chern classes in certain equivariant cohomology groups of $X$ with twisted integer coefficients. We show that these classes determine the (non-equivariant) C...

  18. On hereditary Helly classes of graphs

    OpenAIRE

    Marina Groshaus; Jayme Luiz Szwarcfiter

    2008-01-01

    In graph theory, the Helly property has been applied to families of sets, such as cliques, disks, bicliques, and neighbourhoods, leading to the classes of clique-Helly, disk-Helly, biclique-Helly, neighbourhood-Helly graphs, respectively. A natural question is to determine for which graphs the corresponding Helly property holds, for every induced subgraph. This leads to the corresponding classes of hereditary clique-Helly, hereditary disk-Helly, hereditary biclique-Helly and hereditar...

  19. Class Teacher Candidates’ Views About Drama Applications

    OpenAIRE

    POLAT, Hüseyin

    2014-01-01

    This study aims to determine the views of the students attending education faculty, primary teaching program about drama class applications. The research was conducted in a survey model, and the participants of the research consist of 3rd grade students at primary teaching department of education faculty at Adiyaman university in 2011-2012 academic year and attending the drama lectures given by the research-er. The conclusions showed that drama class applications had positive contribution to ...

  20. Effective Language Teaching in Large Classes

    Institute of Scientific and Technical Information of China (English)

    张丽丽

    2010-01-01

    <正>With more and more people who are jumping into the line of learning the second language (especially English),and also due to the limited resources in language teaching,many foreign language teachers are nowadays confronting the large classes when teaching.So how to teach foreign language effectively in large classes has become an issue as well as a special field to make researches in.

  1. Gas production by depressurization from hypothetical Class 1G and Class 1W hydrate reservoirs

    International Nuclear Information System (INIS)

    We study gas production from two types of Class 1 deposits: a Class 1G hydrate deposit (gas in the hydrate zone) and a Class 1W hydrate deposit (water in the hydrate zone). During production from these reservoirs, a secondary dissociation front appears at the top of the hydrate interval and advances downward, while the original hydrate interface moves upward. Wellbore heating is important to production from Class 1W accumulations, but does not appear to have a significant effect during production from Class 1G deposits. This study indicates that hydrates make significant contributions to gas production from Class 1 deposits. Over a 20-year period, hydrate dissociation contributes up to 50% of the production rate and up to 38% of the cumulative volume of produced gas in the case of the Class 1G deposits, while the corresponding numbers for the Class 1W reservoir are up to 60% and 32%, respectively. During production, hydrate lenses (bands of alternating high-low hydrate saturation) develop in both Class 1W and Class 1G deposits

  2. CLASS: The Cosmology Large Angular Scale Surveyor

    CERN Document Server

    Essinger-Hileman, Thomas; Amiri, Mandana; Appel, John W; Araujo, Derek; Bennett, Charles L; Boone, Fletcher; Chan, Manwei; Cho, Hsiao-Mei; Chuss, David T; Colazo, Felipe; Crowe, Erik; Denis, Kevin; Dünner, Rolando; Eimer, Joseph; Gothe, Dominik; Halpern, Mark; Harrington, Kathleen; Hilton, Gene; Hinshaw, Gary F; Huang, Caroline; Irwin, Kent; Jones, Glenn; Karakla, John; Kogut, Alan J; Larson, David; Limon, Michele; Lowry, Lindsay; Marriage, Tobias; Mehrle, Nicholas; Miller, Amber D; Miller, Nathan; Moseley, Samuel H; Novak, Giles; Reintsema, Carl; Rostem, Karwan; Stevenson, Thomas; Towner, Deborah; U-Yen, Kongpop; Wagner, Emily; Watts, Duncan; Wollack, Edward; Xu, Zhilei; Zeng, Lingzhen

    2014-01-01

    The Cosmology Large Angular Scale Surveyor (CLASS) is an experiment to measure the signature of a gravita-tional-wave background from inflation in the polarization of the cosmic microwave background (CMB). CLASS is a multi-frequency array of four telescopes operating from a high-altitude site in the Atacama Desert in Chile. CLASS will survey 70\\% of the sky in four frequency bands centered at 38, 93, 148, and 217 GHz, which are chosen to straddle the Galactic-foreground minimum while avoiding strong atmospheric emission lines. This broad frequency coverage ensures that CLASS can distinguish Galactic emission from the CMB. The sky fraction of the CLASS survey will allow the full shape of the primordial B-mode power spectrum to be characterized, including the signal from reionization at low $\\ell$. Its unique combination of large sky coverage, control of systematic errors, and high sensitivity will allow CLASS to measure or place upper limits on the tensor-to-scalar ratio at a level of $r=0.01$ and make a cosmi...

  3. CLASS: The Cosmology Large Angular Scale Surveyor

    Science.gov (United States)

    Essinger-Hileman, Thomas; Ali, Aamir; Amiri, Mandana; Appel, John W.; Araujo, Derek; Bennett, Charles L.; Boone, Fletcher; Chan, Manwei; Cho, Hsiao-Mei; Chuss, David T.; Colazo, Felipe; Crowe, Erik; Denis, Kevin; Dunner, Rolando; Eimer, Joseph; Gothe, Dominik; Halpern, Mark; Kogut, Alan J.; Miller, Nathan; Moseley, Samuel; Rostem, Karwan; Stevenson, Thomas; Towner, Deborah; U-Yen, Kongpop; Wollack, Edward

    2014-01-01

    The Cosmology Large Angular Scale Surveyor (CLASS) is an experiment to measure the signature of a gravitational wave background from inflation in the polarization of the cosmic microwave background (CMB). CLASS is a multi-frequency array of four telescopes operating from a high-altitude site in the Atacama Desert in Chile. CLASS will survey 70% of the sky in four frequency bands centered at 38, 93, 148, and 217 GHz, which are chosen to straddle the Galactic-foreground minimum while avoiding strong atmospheric emission lines. This broad frequency coverage ensures that CLASS can distinguish Galactic emission from the CMB. The sky fraction of the CLASS survey will allow the full shape of the primordial B-mode power spectrum to be characterized, including the signal from reionization at low-length. Its unique combination of large sky coverage, control of systematic errors, and high sensitivity will allow CLASS to measure or place upper limits on the tensor-to-scalar ratio at a level of r = 0:01 and make a cosmic-variance-limited measurement of the optical depth to the surface of last scattering, tau. (c) (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.

  4. Adenovirus E1A gene autorepression: revertants of an E1A promoter mutation encode altered E1A proteins

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, P.L.; Tibbetts, C.

    1987-12-01

    Revertants have been isolated from Ad3hr15, a mutant of human adenovirus type 3 that carries a defective E1A promoter. Transcription of these revertant E1A genes is restored - from nil for Ad3hr15 mutant to levels exceeding that of the wild-type virus. The mutant Ad3hr15 virus and the revertants all have an aberrant E1A promoter that contains two short tandem duplications of viral DNA sequence. The E1A gene-coding region of the mutant is the same as that for wild-type adenovirus type 3, whereas the revertants are characterized by short in-frame deletions within the 5' exon region of their E1A genes. Location of these reverting, second-site deletions is discussed in relation to E1A gene autoregulation and the evolved diversity of E1A-related oncogenic potential among different human adenoviruses.

  5. Minimum Data Set Q1a Report

    Data.gov (United States)

    U.S. Department of Health & Human Services — The MDS Q1a report summarizes, by state and county, percentages of residents that answered Yes to Q1a - Residents expresses or indicates preference to return to the...

  6. Generation of proper classes of short exact sequences

    OpenAIRE

    Ali Pancar

    1997-01-01

    The generation of proper classes of short exact sequences of modules by subclasses is considered. The class generated by two proper classes is studied by means of some operations between these classes. These operations are investigated in details for classes of short quasi-splitting, torsion-splitting and pure exact sequences of abelian groups.

  7. Interferon Beta-1a Intramuscular Injection

    Science.gov (United States)

    Interferon beta-1a intramuscular injection is used to reduce the number of episodes of symptoms and slow the development of disability in patients ... Interferon beta-1a intramuscular injection comes as a powder in vials to be mixed into a solution for injection. Interferon beta-1a intramuscular ...

  8. APPLICATION OF TWO OPERATORS TRANSFORM FROM CLASS A OPERATOR TO THE CLASS OF HYPONORMAL OPERATOR

    Institute of Scientific and Technical Information of China (English)

    Yang Changsen; Ding Yanfeng

    2011-01-01

    In this article, we give an operator transform (∧T)(*) from class A operator to the class of hyponormal operators. It is different from the operator transform (∧T) defined by M.Chō and T. Yamazaki. Then, we show that σ(T) = σ(∧T)(*)) and σa(T)\\{0} = σa(∧T)(*))\\{0},in case T belongs to class A. Next, we obtain some relations between (∧T) and (∧T)(*).

  9. Dentofacial characteristics of patients with Angle Class I and Class II malocclusions

    Directory of Open Access Journals (Sweden)

    Rogério Lacerda dos Santos

    2012-04-01

    Full Text Available OBJECTIVE: The present study assessed some cephalometric measurements of the soft tissue profile in order to observe the behavior of facial convexity in patients with Class I, Class II division 1, and Class II division 2 malocclusions. METHODS: One hundred and thirty pre-treatment teleradiographs of Caucasian patients aged 10-16 years (mean age of 12.6 years were selected for study and divided into 3 groups. The cephalometric measurements used in the present study were the following: H.SN, Cx, NLA, MLA, UL-SUL-S, LL-S, IMPA, and 1-SN. Analysis of variance and Tukey's test were applied for measurements H.SN, Cx, IMPA, 1-SN, MLA, and NLA, whereas Kruskal-Wallis and Dunn's tests were applied for UL-S and LL-S. RESULTS: The results showed statistically significant differences for the measurements H.SN, Cx, UL-S, and IMPA between Groups I, II-1 and II-2 (p < 0.05. Measurements LL-S and MLA showed statistically significant difference between Groups I and II-1 only (p < 0.05. On the other hand, no statistically significant differences were found for measurement NLA among the 3 groups (p < 0.05. CONCLUSION: Regarding facial characteristics expressed by measurements H.SN, Cx, and UL-S, one could conclude that Class II division 1 and Class II division 2 malocclusions, both differed from Class I malocclusion. In addition, Class II division 1 malocclusion was found to have facial characteristics expressed by MLA, which differentiate it from the Class II division 2 and Class 1 malocclusions. Class I, Class II division 1 and Class II division 2 malocclusions showed no difference in facial characteristics expressed by the measurement NLA, and measurement LL-S was directly related to eversion of the lower lip.

  10. Students' different understandings of class diagrams

    Science.gov (United States)

    Boustedt, Jonas

    2012-03-01

    The software industry needs well-trained software designers and one important aspect of software design is the ability to model software designs visually and understand what visual models represent. However, previous research indicates that software design is a difficult task to many students. This article reports empirical findings from a phenomenographic investigation on how students understand class diagrams, Unified Modeling Language (UML) symbols, and relations to object-oriented (OO) concepts. The informants were 20 Computer Science students from four different universities in Sweden. The results show qualitatively different ways to understand and describe UML class diagrams and the "diamond symbols" representing aggregation and composition. The purpose of class diagrams was understood in a varied way, from describing it as a documentation to a more advanced view related to communication. The descriptions of class diagrams varied from seeing them as a specification of classes to a more advanced view, where they were described to show hierarchic structures of classes and relations. The diamond symbols were seen as "relations" and a more advanced way was seeing the white and the black diamonds as different symbols for aggregation and composition. As a consequence of the results, it is recommended that UML should be adopted in courses. It is briefly indicated how the phenomenographic results in combination with variation theory can be used by teachers to enhance students' possibilities to reach advanced understanding of phenomena related to UML class diagrams. Moreover, it is recommended that teachers should put more effort in assessing skills in proper usage of the basic symbols and models and students should be provided with opportunities to practise collaborative design, e.g. using whiteboards.

  11. PLGG1, a plastidic glycolate glycerate transporter, is required for photorespiration and defines a unique class of metabolite transporters

    OpenAIRE

    Pick, Thea R; Bräutigam, Andrea; Schulz, Matthias A.; Obata, Toshihiro; Fernie, Alisdair R.; Weber, Andreas P. M.

    2013-01-01

    Photorespiratory carbon flux reaches up to a third of photosynthetic flux, thus contributes massively to the global carbon cycle. The pathway recycles glycolate-2-phosphate, the most abundant byproduct of RubisCO reactions. This oxygenation reaction of RubisCO and subsequent photorespiration significantly limit the biomass gains of many crop plants. Although photorespiration is a compartmentalized process with enzymatic reactions in the chloroplast, the peroxisomes, the mitochondria, and the ...

  12. Group cohesion in exercise classes: An examination of gender and type of exercise class differences

    Directory of Open Access Journals (Sweden)

    Hülya Aşçı

    2011-10-01

    Full Text Available Group cohesion has been attributed to the higher levels of attendance and performance and lower levels of drop-outs in exercise classes. Cohesion can be affected by different type of exercise classes and gender. Therefore, the main purpose of the study was to compare the group cohesion levels of martial arts participants (aikido, taekwondo, karate, and kendo with aerobic-like participants (aerobics, aero-steps, phys-gym, and high-low aerobics. This causal comparative study also aimed at examining sex differences in group cohesion in exercise classes. There were 140 participants (Mage=28.1 SD= 8.01 and female= 138 male= 2 in aerobic-like classes and 137 participants (Mage= 22.2 SD= 3.8 and female= 48 male= 89 in martial arts classes. Results revealed no sex differences between the groups on the perceptions of cohesion. On the other hand, except for individual attractions to the group-task dimension, participants of martial art classes had higher levels of group cohesion than the participants of aerobic-like classes. Consequently, it was concluded that different types of exercise classes may have different levels of cohesion and those differences were discussed within the context of exercise classes.

  13. A Small Special Needs Class or a Smaller Class at the Beginning of the Educational Path?

    OpenAIRE

    Valli, Raine; Jokinen, Katja

    2016-01-01

    This article is based on the case study which focuses on the small class (in this article used to describe a small special needs class) operation of one medium-sized Finnish town. In the study an attempt was made to clarify what kind of alternative the small class is to the first grade of general education at the beginning of the child's educational path, what kind of experiences the teachers had of the pupils of the small class, of multi-vocational cooperation and of pupils' i...

  14. Group cohesion in exercise classes: An examination of gender and type of exercise class differences

    Directory of Open Access Journals (Sweden)

    Selçuk Akpınar

    2011-10-01

    Full Text Available Group cohesion has been attributed to the higher levels of attendance and performance and lower levels of drop-outs in exercise classes. Cohesion can be affected by different type of exercise classes and gender. Therefore, the main purpose of the study was to compare the group cohesion levels of martial arts participants (aikido, taekwondo, karate, and kendo with aerobic-like participants (aerobics, aero-steps, phys-gym, and high-low aerobics. This causal comparative study also aimed at examining gender differences in group cohesion in exercise classes. There were 140 participants (Mage=28.1 SD= 8.01 and female= 138 male= 2 in aerobic-like classes and 137 participants (Mage= 22.2 SD= 3.8 and female= 48 male= 89 in martial arts classes. Results revealed no gender differences between the groups on the perceptions of cohesion. On the other hand, except for individual attractions to the group-task dimension, participants of martial art classes had higher levels of group cohesion than the participants of aerobic-like classes. Consequently, it was concluded that different types of exercise classes may have different levels of cohesion and those differences were discussed within the context of exercise classes

  15. Classes and Theories of Trees Associated with a Class Of Linear Orders

    DEFF Research Database (Denmark)

    Goranko, Valentin; Kellerman, Ruaan

    2011-01-01

    classes of trees and between their corresponding first-order theories. We then obtain some general results about the axiomatization of the first-order theories of some of these classes of trees in terms of the first-order theory of the generating class C, and indicate the problems obstructing such general...... results for the other classes. These problems arise from the possible existence of nondefinable paths in trees, that need not satisfy the first-order theory of C, so we have started analysing first order definable and undefinable paths in trees....

  16. Evaluation depth of the curve of Spee in class I, class II, and class III malocclusion: A cross sectional study

    Directory of Open Access Journals (Sweden)

    Sanjna Nayar

    2015-01-01

    Full Text Available Occlusal plane is an essential consideration when multiple long-span posterior restorations are designed. When restorations are added to an existing tooth arrangement characterized by rotated, tipped, or extruded teeth, excursive interferences may be incorporated, resulting in detrimental squeal. The curve of Spee, which exists in the ideal natural dentition, allows harmony to exist between the anterior tooth and condylar guidance. This curve exists in the sagittal plane and is the best viewed from a lateral aspect. It permits total posterior disclusion on mandibular protrusion, given proper anterior tooth guidance. It is unclear that whether the curve of Spee is a description of the occlusal surface of each arch separately or in maximal intercuspation. The purpose of this study was to examine the differences in the depth of curve of Spee between the class I, class II, class III and to investigate the relationship of depth of curve of Spee with over jet, over-bite.

  17. Social class, anxieties and mothers' foodwork.

    Science.gov (United States)

    Wright, Jan; Maher, JaneMaree; Tanner, Claire

    2015-03-01

    In the context of concerns about childhood obesity, mothers are placed at the forefront of responsibility for shaping the eating behaviour and consequently the health of their young children. This is evident in a multitude of diverse sites such as government reports, health promotion materials, reality TV shows and the advice of childcare nurses and preschools. These sites produce a range of resources available to mothers to draw on to constitute themselves as mothers in terms of caring for their children's health. Drawing on a qualitative study of mothers recruited through three Australian preschool centres, this article examines how the working-class and middle-class mothers of preschool-aged children engage with knowledge about motherhood, children and health and how those engagements impact on their mothering, their foodwork and their children. We argue that, unlike the working-class mothers pathologised in some literature on obesity, these working-class mothers demonstrated a no-nonsense (but still responsibilised) approach to feeding their children. The middle-class mothers, on the other hand, were more likely to engage in practices of self-surveillance and to demonstrate considerable anxieties about the appropriateness of their practices for their children's current and future health. PMID:25677342

  18. Fibonacci family of dynamical universality classes.

    Science.gov (United States)

    Popkov, Vladislav; Schadschneider, Andreas; Schmidt, Johannes; Schütz, Gunter M

    2015-10-13

    Universality is a well-established central concept of equilibrium physics. However, in systems far away from equilibrium, a deeper understanding of its underlying principles is still lacking. Up to now, a few classes have been identified. Besides the diffusive universality class with dynamical exponent [Formula: see text], another prominent example is the superdiffusive Kardar-Parisi-Zhang (KPZ) class with [Formula: see text]. It appears, e.g., in low-dimensional dynamical phenomena far from thermal equilibrium that exhibit some conservation law. Here we show that both classes are only part of an infinite discrete family of nonequilibrium universality classes. Remarkably, their dynamical exponents [Formula: see text] are given by ratios of neighboring Fibonacci numbers, starting with either [Formula: see text] (if a KPZ mode exist) or [Formula: see text] (if a diffusive mode is present). If neither a diffusive nor a KPZ mode is present, all dynamical modes have the Golden Mean [Formula: see text] as dynamical exponent. The universal scaling functions of these Fibonacci modes are asymmetric Lévy distributions that are completely fixed by the macroscopic current density relation and compressibility matrix of the system and hence accessible to experimental measurement. PMID:26424449

  19. Disordered cold atoms in different symmetry classes

    Science.gov (United States)

    Pinheiro, Fernanda; Larson, Jonas

    2015-08-01

    We consider an experimentally realizable model of noninteracting but randomly coupled atoms in a two-dimensional optical lattice. By choosing appropriate real or complex-valued random fields and species-dependent energy offsets, this system can be used to analyze effects of disorder in four different symmetry classes: the chiral BDI and AIII and the nonchiral A and AI. These chiral classes are known to support a metallic phase at zero energy, which here, due to the inevitable finite size of the system, should also persist in a neighborhood of nonzero energies. As we discuss, this is of particular interest for experiments involving quenches. Away from the center of the spectrum, we find that excitations appear as domain walls in the cases with time-reversal symmetry or as vortices in the cases where time-reversal symmetry is absent. Therefore, a quench in a system with uniform density would lead to the formation of either vortices or domain walls depending on the symmetry class. For the nonchiral models in classes A and AI, a population imbalance between the two atomic species naturally occurs. In these cases, one of the two species is seen to favor a more uniform density. We also study the onset of localization as the disorder strength is increased for the different classes, and by deriving an effective model for the nonchiral cases we show how their eigenstates remain extended for larger values of the coupling with the disorder when compared to the nonchiral ones.

  20. Software engineering processes for Class D missions

    Science.gov (United States)

    Killough, Ronnie; Rose, Debi

    2013-09-01

    Software engineering processes are often seen as anathemas; thoughts of CMMI key process areas and NPR 7150.2A compliance matrices can motivate a software developer to consider other career fields. However, with adequate definition, common-sense application, and an appropriate level of built-in flexibility, software engineering processes provide a critical framework in which to conduct a successful software development project. One problem is that current models seem to be built around an underlying assumption of "bigness," and assume that all elements of the process are applicable to all software projects regardless of size and tolerance for risk. This is best illustrated in NASA's NPR 7150.2A in which, aside from some special provisions for manned missions, the software processes are to be applied based solely on the criticality of the software to the mission, completely agnostic of the mission class itself. That is, the processes applicable to a Class A mission (high priority, very low risk tolerance, very high national significance) are precisely the same as those applicable to a Class D mission (low priority, high risk tolerance, low national significance). This paper will propose changes to NPR 7150.2A, taking mission class into consideration, and discuss how some of these changes are being piloted for a current Class D mission—the Cyclone Global Navigation Satellite System (CYGNSS).

  1. The Cosmology Large Angular Scale Surveyor (CLASS)

    Science.gov (United States)

    Harrington, Kathleen; Marriange, Tobias; Aamir, Ali; Appel, John W.; Bennett, Charles L.; Boone, Fletcher; Brewer, Michael; Chan, Manwei; Chuss, David T.; Colazo, Felipe; Denis, Kevin; Moseley, Samuel H.; Rostem, Karwan; Wollack, Edward

    2016-01-01

    The Cosmology Large Angular Scale Surveyor (CLASS) is a four telescope array designed to characterize relic primordial gravitational waves from in ation and the optical depth to reionization through a measurement of the polarized cosmic microwave background (CMB) on the largest angular scales. The frequencies of the four CLASS telescopes, one at 38 GHz, two at 93 GHz, and one dichroic system at 145/217 GHz, are chosen to avoid spectral regions of high atmospheric emission and span the minimum of the polarized Galactic foregrounds: synchrotron emission at lower frequencies and dust emission at higher frequencies. Low-noise transition edge sensor detectors and a rapid front-end polarization modulator provide a unique combination of high sensitivity, stability, and control of systematics. The CLASS site, at 5200 m in the Chilean Atacama desert, allows for daily mapping of up to 70% of the sky and enables the characterization of CMB polarization at the largest angular scales. Using this combination of a broad frequency range, large sky coverage, control over systematics, and high sensitivity, CLASS will observe the reionization and recombination peaks of the CMB E- and B-mode power spectra. CLASS will make a cosmic variance limited measurement of the optical depth to reionization and will measure or place upper limits on the tensor-to-scalar ratio, r, down to a level of 0.01 (95% C.L.).

  2. A Curriculum for Teaching Indonesian in Classes with Diverse Learners

    OpenAIRE

    Maria Carreira; Juliana Wijaya

    2010-01-01

    Language classes enrolling heritage language learners are characterized by great student diversity, e.g. different proficiency levels in the target language and culture, as well as in English. This is true for heritage language classes (i.e. classes populated only by heritage language students), as well as mixed-background classes (i.e. classes enrolling both heritage and second language (L2) learners). Attending to the needs of all learners in these classes presents sign...

  3. Communicative Language Teaching in Second Language Class

    Institute of Scientific and Technical Information of China (English)

    Xiao Juan

    2010-01-01

    IntroductionReturn the class to the students and let the students be the masters of the class.This is what I have changed during the last three years in my class.I have been using Communicative Language Teaching method instead of Grammar Translation method.In the Grammar Translation method, students only study grammar and learn lists of words and then translate what they have learned into Chinese.In the classroom,the teacher uses the students' first language to explain the grammar and vocabulary in the text and then helps the students to translate it.This method is based on the idea that language is made up of words and that language changes according to the grammar rules.

  4. A new class of dynamic quantum metamaterials

    CERN Document Server

    Quach, James Q; Martin, Andrew M; Greentree, Andrew D; Hollenberg, Lloyd C L

    2010-01-01

    Controllable quantum systems are heralding a quantum technology revolution. By coupling controllable quantum systems into larger structures we introduce the concept of a quantum metamaterial. Conventional metamaterials represent one the most important frontiers in optical design, with applications in diverse fields ranging from medicine to aerospace. Up until now however, metamaterials have themselves been classical structures and interact only with the classical properties of light. Here we describe a class of dynamic metamaterials, based on the quantum properties of coupled atom-cavity arrays, which are intrinsically lossless, reconfigurable, and operate fundamentally at the quantum level. We show how this new class of metamaterial could be used to create a reconfigurable quantum superlens possessing a negative index gradient for single photon imaging. With the inherent features of quantum superposition and entanglement of metamaterial properties, this new class of dynamic quantum metamaterial, opens a new ...

  5. A GENERALIZED CLASS OF PSNR SAMPLING SCHEME

    Directory of Open Access Journals (Sweden)

    D. Shukla

    2010-01-01

    Full Text Available In the present days of advanced electronic technologies in the field of communicationlike mobile phones, e-mail, internet etc. (and so forth the incentive based mail surveys are beingpopular due to their cost effectiveness and rapid approach to individuals. But, a majordisadvantage appears as mail surveys are affected by a huge amount of non-response of units inthe sample. The post-stratified non-response (PSNR scheme is used, in the stratified samplingset-up, when (i frames of stratum are unknown and (ii strata contain some non-responding units.This paper presents a general class of PSNR type sampling scheme by introducing three groupsof earmarked strata based on response pattern along-with two parameters pf the class. TheBayesian approach regarding utilization of prior knowledge (or guess of response pattern isintroduced in the proposed class for estimating the population mean. Several properties of theclass are derived and the results are numerically supported.

  6. Type Ibn Supernovae: Not a Single Class

    Science.gov (United States)

    Hosseinzadeh, Griffin; Arcavi, Iair; Howell, Dale Andrew; McCully, Curtis; Valenti, Stefano

    2016-01-01

    Type Ibn supernovae are a small yet diverse class of explosions whose spectra are characterized by low-velocity helium emission lines. The prevailing theory has been that these are the core-collapse explosions of very massive stars embedded in helium-rich circumstellar material. However, unlike the more common Type IIn supernovae, whose interaction with hydrogen-rich circumstellar material has been shown to generate a wide variety of light curve shapes, we find that light curves of Type Ibn supernovae are more homogeneous and faster evolving. Spectroscopically, we find that Type Ibn supernovae divide cleanly into two classes, only one of which resembles the archetypal Type Ibn SN 2006jc. We explore various photometric and spectroscopic parameter spaces in order to characterize these two classes. We consider the possibility that not all objects classified as Type Ibn have the same physical origin.

  7. Education, class and vernacular awareness on Tyneside

    DEFF Research Database (Denmark)

    Jensen, Marie Møller

    2017-01-01

    This paper reports on a questionnaire study investigating Tyneside residents’ vernacular awareness and attested language use. Participant performance is interpreted on the basis of a cross-tabulation of participants’ social class as determined by their level of education and participants’ own...... identification. The results indicate that participants’ self-identification is at odds with the classification based on education and, furthermore, that the group of participants who identify as middle class but have low educational attainment behave significantly different from the other participants. This...... group consisted of mainly older female speakers and results are interpreted in light of first wave studies on the patterning of language use by class, age and gender. Finally, the issue of vernacular awareness is linked to social indexicality and it is suggested that an interpretation of participants as...

  8. Deployment of a class 2 tensegrity boom

    Science.gov (United States)

    Pinaud, Jean-Paul; Solari, Soren; Skelton, Robert E.

    2004-07-01

    Tensegrity structures are special truss structures composed of bars in compression and cables in tension. Most tensegrity structures under investigation, to date, have been of Class 1, where bars do not touch. In this article, however, we demonstrate the hardware implementation of a 2 stage symmetric Class 2 tensegrity structure, where bars do connect to each other at a pivot. The open loop control law for tendon lengths to accomplish the desired geometric reconfiguration are computed analytically. The velocity of the structure's height is chosen and reconfiguration is accomplished in a quasi-static manner, ignoring dynamic effects. The main goal of this research was to design, build, and test the capabilities of the Class 2 structure for deployment concepts and to further explore the possibilities of multiple stage structures using the same design and components.

  9. Preventing Academic Dishonesty in Online Classes

    Institute of Scientific and Technical Information of China (English)

    薛淑娟; 孙童真

    2015-01-01

    Abstract:The purpose of this paper is to look into the manner of cheating in online course environment and explore the prevention measures to stop cheating. This paper is designed to address two research questions: 1) What are the types of cheating happening in online classes from the perspectives of instructors or students in online classes? 2) What are preventive measures to stop cheating in online classes? The questionnaire used in this research tests the prevalence of academic dishonesty and the methods of cheating in online courses. Data will be collected through a survey from students who take online course during the 2013 spring semester. This paper will present practical suggestions to reduce the frequency of cheating among students enrolling in online courses.

  10. Class field theory. The Bonn lectures

    International Nuclear Information System (INIS)

    Clear presentation. Quick and immediate access to the subject. A classic (established and prominent German original). The present manuscript is an improved edition of a text that first appeared under the same title in Bonner Mathematische Schriften, no.26, and originated from a series of lectures given by the author in 1965/66 in Wolfgang Krull's seminar in Bonn. Its main goal is to provide the reader, acquainted with the basics of algebraic number theory, a quick and immediate access to class field theory. This script consists of three parts, the first of which discusses the cohomology of finite groups. The second part discusses local class field theory, and the third part concerns the class field theory of finite algebraic number fields.

  11. Class field theory from theory to practice

    CERN Document Server

    Gras, Georges

    2003-01-01

    Global class field theory is a major achievement of algebraic number theory, based on the functorial properties of the reciprocity map and the existence theorem. The author works out the consequences and the practical use of these results by giving detailed studies and illustrations of classical subjects (classes, idèles, ray class fields, symbols, reciprocity laws, Hasse's principles, the Grunwald-Wang theorem, Hilbert's towers,...). He also proves some new or less-known results (reflection theorem, structure of the abelian closure of a number field) and lays emphasis on the invariant (/cal T) p, of abelian p-ramification, which is related to important Galois cohomology properties and p-adic conjectures. This book, intermediary between the classical literature published in the sixties and the recent computational literature, gives much material in an elementary way, and is suitable for students, researchers, and all who are fascinated by this theory. In the corrected 2nd printing 2005, the author improves s...

  12. 40 CFR 82.11 - Exports of class I controlled substances to Article 5 Parties.

    Science.gov (United States)

    2010-07-01

    ... substances to Article 5 Parties. 82.11 Section 82.11 Protection of Environment ENVIRONMENTAL PROTECTION... Controls § 82.11 Exports of class I controlled substances to Article 5 Parties. (a) If apportioned Article... substances) to foreign states listed in appendix E to this subpart (Article 5 countries). (1) A person...

  13. 78 FR 21044 - Amendment of Class D and Class E Airspace; Reading, PA

    Science.gov (United States)

    2013-04-09

    ... amend Class D and Class E airspace at Reading, PA (78 FR 5754) Docket No. FAA-2012-1270. Interested... rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not..., 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation...

  14. Affluence, Class Structure, and Working-Class Consciousness in Modern Spain

    Science.gov (United States)

    Logan, John R.

    1977-01-01

    A survey of textile workers in Barcelona indicates that the growing proportion of affluent workers in Spain has become a major source of class consciousness, militancy, and politicization. A theoretical framework is presented which interprets the survey findings in terms of the relationship between affluence and class consciousness. (Author/DB)

  15. Social Class and Social Action: The Middle-Class Bias of Democratic Theory in Education

    Science.gov (United States)

    Schutz, Aaron

    2008-01-01

    Background: This article examines the emergence of the middle and working classes in America and describes key characteristics of these cultures as they manifest themselves today. It then explores the effects of social class on our conceptions of democracy. Purpose: To help educators understand the relationship between social action strategies and…

  16. Class Discussions: Locating Social Class in Novels for Children and Young Adults

    Science.gov (United States)

    McLeod, Cynthia Anne

    2008-01-01

    Few studies on representations of social class in children's literature have been published in the United States. As a language arts teacher and media specialist in a high poverty school, the author describes children's novels that directly address social class and the subtopic of the labor movement and consider the continued relevance of social…

  17. Social Class Experiences of Working-Class Students: Transitioning out of College

    Science.gov (United States)

    Treager Huber, Carey

    2010-01-01

    Issues surrounding social class are often overlooked and rarely discussed in higher education; however, they affect students and institutions in critical ways. Although research has demonstrated that social class is a predictor of access to college, retention, academic performance, overall undergraduate and graduate experience, and college…

  18. Comparison of Group Cohesion, Class Participation, and Exam Performance in Live and Online Classes

    Science.gov (United States)

    Galyon, Charles E.; Heaton, Eleanore C. T.; Best, Tiffany L.; Williams, Robert L.

    2016-01-01

    Though class participation and group cohesion have shown some potential to promote student performance in conventional classrooms, their efficacy has not yet been demonstrated in an online-class setting. Group cohesion, defined as member attraction to and self-identification with a group, is thought to promote positive interdependence and the…

  19. Reading in Class & out of Class: An Experience Sampling Method Study

    Science.gov (United States)

    Shumow, Lee; Schmidt, Jennifer A.; Kackar, Hayal

    2008-01-01

    This study described and compared the reading of sixth and eighth grade students both in and out of school using a unique data set collected with the Experience Sampling Method (ESM). On average, students read forty minutes a day out of class and seventeen minutes a day in class indicating that reading is a common leisure practice for…

  20. The class of n-entire operators

    International Nuclear Information System (INIS)

    We introduce a classification of simple, regular, closed symmetric operators with deficiency indices (1, 1) according to a geometric criterion that extends the classical notions of entire operators and entire operators in the generalized sense due to M G Krein. We show that these classes of operators have several distinctive properties, some of them related to the spectra of their canonical self-adjoint extensions. In particular, we provide necessary and sufficient conditions on the spectra of two canonical self-adjoint extensions of an operator for it to belong to one of our classes. Our discussion is based on some recent results in the theory of de Branges spaces. (paper)

  1. A Simple Class of Measures of Skewness

    OpenAIRE

    ALTINAY, Galip

    2016-01-01

    In this paper, a simple class of measures for detecting skewness in samples is introduced. The new class of measures is based on a new definition of skewness that takes midrange into consideration. The proposed coefficients of skewness can be computed easily with only three of the summary statistics, i.e., the minimum value, the maximum value and the median (or the mode, or the mean). Another advantage of the new statistics is that they are bounded by -1 and +1, hence, the coefficients of ske...

  2. On Finite Groups with Special Conjugacy Classes

    Institute of Scientific and Technical Information of China (English)

    DU Xiang-lin

    2007-01-01

    Let G be a finite group with the property that for any conjugacy class order, G has exactly two conjugacy classes which have the same order. We prove that:(1) if a Sylow 2-subgroup of G is Abelian, then G is isomorphic to the direct product of symmetric group with order 3 and cyclic group with order 2, or G is isomorphic to the semidirect product of a cyclic group with order 3 and a cyclic group with order 4; (2) if G' is nilpotent, then G is a group of {2,3,5}.

  3. System Model Semantics of Class Diagrams

    OpenAIRE

    Cengarle, Maria Victoria; Grönninger, Hans; Rumpe, Bernhard

    2014-01-01

    Defining semantics for UML is a difficult task. Disagreements in the meaning of UML constructs as well as the size of UML are major obstacles. In this report, we describe our approach to define the semantics for UML. Semantics is defined denotationally as a mapping into our semantics domain called the system model [4, 5, 6]. We demonstrate our approach by defining the semantics for a comprehensive version of class diagrams. The semantics definition is detailed for UML/P class diagrams, a vari...

  4. Characteristic classes of quantum principal bundles

    CERN Document Server

    Durdevic, M

    1995-01-01

    A noncommutative-geometric generalization of classical Weil theory of characteristic classes is presented, in the conceptual framework of quantum principal bundles. A particular care is given to the case when the bundle does not admit regular connections. A cohomological description of the domain of the Weil homomorphism is given. Relations between universal characteristic classes for the regular and the general case are analyzed. In analogy with classical geometry, a natural spectral sequence is introduced and investigated. The appropriate counterpart of the Chern character is constructed, for structures admitting regular connections. Illustrative examples and constructions are presented.

  5. On a class of topological groups

    Directory of Open Access Journals (Sweden)

    Dinamérico P. Pombo Jr

    2006-11-01

    Full Text Available A topological group is an SNS-group if its identity element possessesa fundamental system of neighborhoods formed by normal subgroups. In this paper we prove the existence of initial SNS-topologies, from which we derive that the class of SNS-groups is closed under the formation of products and projective limits, and we prove the existence of final SNS-topologies, from which we derive that the class of SNS-groups is closed under the formation of free products and inductive limits.

  6. Weak equivalence classes of complex vector bundles

    OpenAIRE

    Hông-Vân Lê

    2006-01-01

    For any complex vector bundle Ek of rank k over a manifold Mm with Chern classes ci Î H2i(Mm, Z) and any non-negative integers l1, . . ., lk we show the existence of a positive number p(m, k) and the existence of a complex vector bundle Êk over Mm whose Chern classes are p(m, k) × li × ci Î H2i(Mm, Z). We also discuss a version of this statement for holomorphic vector bundles over projective algebraic manifolds.

  7. An Analysis on an ESL Class

    Institute of Scientific and Technical Information of China (English)

    杜岳青

    2015-01-01

    Input is the precondition of interaction and output while output promotes the input and the interaction of language,which could increase the effectiveness of input and enhance the chance of the absorption of interaction.By analyzing an ESL class,this paper gives readers a picture of how the second language (SL) learners get information,absorb and digest the information,produce language and form their language system in their SL learning.At last,it gives suggestions on how to ensure language learners have a better chance to get comprehensible input,assimilate language during interaction and output more accurate and comprehensible second language in an ESL class.

  8. Class specific antibody response to gonococcal infection.

    OpenAIRE

    Miettinen, A; Hakkarainen, K; Grönroos, P; Heinonen, P.; Teisala, K; Aine, R; Sillantaka, I; Saarenmaa, K; Lehtinen, M; Punnonen, R

    1989-01-01

    An enzyme immunoassay was used to determine IgM, IgG, and IgA antibodies to gonococcal pili in 68 patients with uncomplicated gonorrhoea, 35 women with pelvic inflammatory disease, and in 115 normal controls. A clear difference in response rate in all three antibody classes between patients with gonorrhoea and healthy controls was evident. Among women with gonorrhoea, the magnitude of antibody response was higher than among men with gonorrhoea, especially in the IgM class. No major difference...

  9. Designing a new class of distributed systems

    CERN Document Server

    Mikkilineni, Rao

    2011-01-01

    Designing a New Class of Distributed Systems closely examines the Distributed Intelligent Managed Element (DIME) Computing Model, a new model for distributed systems, and provides a guide to implementing Distributed Managed Workflows with High Reliability, Availability, Performance and Security. The book also explores the viability of self-optimizing, self-monitoring autonomous DIME-based computing systems. Designing a New Class of Distributed Systems is designed for practitioners as a reference guide for innovative distributed systems design. Researchers working in a related field will also f

  10. GOALS OF PARTICIPATION IN PHYSICAL EDUCATION CLASSES

    OpenAIRE

    Rahim Ramzaninezhad; Farhad Rahmaninia; Mehr Ali Hemmatinezhad; Nooshin Benar; Misagh Hoseini Keshtan

    2011-01-01

    The importance of physical education in school life and for health points to the need to the better understands goal's participation of students in school education classes. This study was an attempt to investigate students' goals for participates in physical education (PE) classes. 455 random out of 72673 students of junior and senior high schools with the age range of 11 to 19 years (M=14.67). A 28-items survey was administrated to assess (a) demographics and (b) Purposes for Engaging in Ph...

  11. The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2.

    Science.gov (United States)

    Glenewinkel, Florian; Cohen, Michael J; King, Cason R; Kaspar, Sophie; Bamberg-Lemper, Simone; Mymryk, Joe S; Becker, Walter

    2016-01-01

    DYRK1A is a constitutively active protein kinase that has a critical role in growth and development which functions by regulating cell proliferation, differentiation and survival. DCAF7 (also termed WDR68 or HAN11) is a cellular binding partner of DYRK1A and also regulates signalling by the protein kinase HIPK2. DCAF7 is an evolutionarily conserved protein with a single WD40 repeat domain and has no catalytic activity. We have defined a DCAF7 binding motif of 12 amino acids in the N-terminal domain of class 1 DYRKs that is functionally conserved in DYRK1 orthologs from Xenopus, Danio rerio and the slime mold Dictyostelium discoideum. A similar sequence was essential for DCAF7 binding to HIPK2, whereas the closely related HIPK1 family member did not bind DCAF7. Immunoprecipitation and pulldown experiments identified DCAF7 as an adaptor for the association of the adenovirus E1A protein with DYRK1A and HIPK2. Furthermore, DCAF7 was required for the hyperphosphorylation of E1A in DYRK1A or HIPK2 overexpressing cells. Our results characterize DCAF7 as a substrate recruiting subunit of DYRK1A and HIPK2 and suggest that it is required for the negative effect of DYRK1A on E1A-induced oncogenic transformation. PMID:27307198

  12. Class Size and Cost in ADN Programs

    Science.gov (United States)

    Boehret, Alice C.; Larowe, Ann

    1978-01-01

    The article discusses the cost-effective use of faculty and facilities in associate degree nursing programs, as a large number of programs with small classes is uneconomical. Appraisal of admissions to reach an enrollment level sufficient to justify program cost is suggested. (MF)

  13. A new class of spontaneously polarized materials

    DEFF Research Database (Denmark)

    Field, David; Plekan, Oksana; Cassidy, Andrew;

    2011-01-01

    Very large electric fields form spontaneously within films of seemingly prosaic chemicals such as nitrous oxide or propane.We describe how the discovery of this unexpected phenomenon took place and how we attempt to understand the nature of the new class of spontaneously polarized materials...

  14. Conformal classes realizing the Yamabe invariant

    OpenAIRE

    Macbeth, Heather

    2014-01-01

    We give a characterization of conformal classes realizing a compact manifold's Yamabe invariant. This characterization is the analogue of an observation of Nadirashvili for metrics realizing the maximal first eigenvalue, and of Fraser and Schoen for metrics realizing the maximal first Steklov eigenvalue.

  15. The Audiolingual Method in Intensive Reading Class

    Institute of Scientific and Technical Information of China (English)

    张晓辉

    2010-01-01

    The Audiolingual Method consists of four steps:recognition,repetition,pattern drills and follow-up reading. The article is about the use of the Audiolingual Method in intensive reading class through the experiment of the students from grade one to grade two.

  16. Economies of Scale and Large Classes

    Science.gov (United States)

    Saiz, Martin

    2014-01-01

    Making classes larger saves money--and public universities across the country have found it a useful strategy to balance their budgets after decades of state funding cuts and increases to infrastructure costs. Where this author teaches, in the College of Social and Behavioral Sciences at California State University, Northridge (CSUN),…

  17. Stability of latent class segments over time

    DEFF Research Database (Denmark)

    Mueller, Simone

    2011-01-01

    Dynamic stability, as the degree to which identified segments at a given time remain unchanged over time in terms of number, size and profile, is a desirable segment property which has received limited attention so far. This study addresses the question to what degree latent classes identified from...

  18. A new class of non-leaves

    CERN Document Server

    Souza, Fábio S

    2011-01-01

    We give examples of open smooth manifolds that cannot be leaves of any Riemannian foliation of arbitrary codimension on a compact manifold. We also present a new class of non-leaves of C^0 codimension one foliations, simply connected manifolds of dimension at least 5 that are non-periodic in homotopy, namely in their 2-dimensional homotopy groups.

  19. Weighted classes of quaternion-valued functions

    OpenAIRE

    A. El-Sayed Ahmed; Omran, Saleh

    2012-01-01

    In this paper, we define the classes $F(p,q,s)$ of quaternion-valued functions, then we characterize quaternion Bloch functions by quaternion $F(p,q,s)$ functions in the unit ball of $\\mathbb{R}^3$. Further, some important basic properties of these functions are also considered.

  20. In Pursuit of the Working Class

    Directory of Open Access Journals (Sweden)

    Ben Clarke

    2013-08-01

    Full Text Available A review of Owen Jones, Chavs: The Demonization of the Working Class (Verso, 2012, Zygmunt Bauman, Collateral Damage: Social Inequalities in a Global Age (Polity, 2011 and David Nichols, The Bogan Delusion: Myths, Mischief and Misconceptions (Affirm, 2011.

  1. The Promise of Single-Sex Classes

    Science.gov (United States)

    Stotsky, Sandra

    2012-01-01

    Despite the enthusiasm and the absence of definitive research on the pros and cons of single-sex classes, a 2011 article in Science, titled "The Pseudoscience of Single-Sex Schooling," by a new organization called American Council for CoEducational Schooling (ACCES) came out with the astonishing conclusion that single-sex education is ineffective…

  2. TV News Analysis Project Motivates Broadcast Class.

    Science.gov (United States)

    Smith, James R.

    1980-01-01

    Describes the use of content analysis by a journalism class in studying television news. Indicates that the method is flexible, generates familiarity with quantitative approaches to the analysis of broadcast journalism, can result in increased awareness of the complexity of the broadcast news medium, and increases student motivation. (TJ)

  3. Apply the Communicative Approach in Listening Class

    Institute of Scientific and Technical Information of China (English)

    Wang; changxue; Su; na

    2014-01-01

    Speaking and listening are the two obstacles in the process of our learning and they are also the most important abilities that we should possess. Communicative approach aims to the ability of learners’ communicative competence, thus apply the communicative approach in listening class is an effective way in English teaching procedure.

  4. Apply the Communicative Approach in Listening Class

    Institute of Scientific and Technical Information of China (English)

    Wang changxue; Su na

    2014-01-01

    Speaking and listening are the two obstacles in the process of our learning and they are also the most important abilities that we should possess. Communicative approach aims to the ability of learners’communicative competence, thus apply the communicative approach in listening class is an effective way in English teaching procedure.

  5. Operating experience with 900 MW class reactors

    International Nuclear Information System (INIS)

    The operating experience of 900 MW class CANDU reactor nuclear power plant is introduced. The performance of Darlington nuclear power plant is very good and continues to improve. The objectives are: superior safety, competitive performance, harmony with the community and environment

  6. Using existing questionnaires in latent class analysis

    DEFF Research Database (Denmark)

    Nielsen, Anne Molgaard; Vach, Werner; Kent, Peter;

    2016-01-01

    BACKGROUND: Latent class analysis (LCA) is increasingly being used in health research, but optimal approaches to handling complex clinical data are unclear. One issue is that commonly used questionnaires are multidimensional, but expressed as summary scores. Using the example of low back pain (LB...

  7. Class Rank Weighs Down True Learning

    Science.gov (United States)

    Guskey, Thomas R.

    2014-01-01

    The process of determining class rank does not help students achieve more or reach higher levels of proficiency. Evidence indicates ranking students may diminish students' motivation. High school educators argue that they are compelled to rank-order graduating students because selective colleges and universities require information about…

  8. JAVA CLASSES FOR NONPROCEDURAL VARIOGRAM MONITORING

    Science.gov (United States)

    A set of Java classes was written for variogram modeling to support research for US EPA's Regional Vulnerability Assessment Program (ReVA). The modeling objectives of this research program are to use conceptual programming tools for numerical analysis for regional risk assessm...

  9. Nuclear class 1 piping stress analysis

    International Nuclear Information System (INIS)

    A nuclear class 1 piping stress analysis, according to the ASME code, is presented. The TRHEAT computer code has been used to determine the piping wall thermal gradient. The Nupipe computer code was employed for the piping stress analysis. Computer results were compared with the allowable criteria from the ASME code. (Author)

  10. Online Discussion Assignments Improve Students' Class Preparation

    Science.gov (United States)

    Lineweaver, Tara T.

    2010-01-01

    To increase the number of students who read the text before class and to promote student interaction centering on text material, I developed an online discussion assignment as a required component of a cognitive psychology course. Across 2 studies, this assignment had a limited effect on examination performance, but students completing online…

  11. Using Nonverbal Communication in Efl Classes

    Directory of Open Access Journals (Sweden)

    Aysenil Barabar

    2015-06-01

    Full Text Available This paper aims at providing information about nonverbal communication and to state its use in EFL classes. Briefly, this paper introduces the definition, aspects and importance of nonverbal communication. Especially, this study explains some ways of using nonverbal communication in EFL classes, in order to have good classroom management in the class. Based upon this assumption, we aimed to shed light on this area of research, by showing that teachers’ nonverbal behaviour plays a highly significant and essential role in foreign language classrooms for managing the students’ behaviour. This study was conducted in Lefke, Northern Cyprus. The participants were two female English language teachers who were working at the English Preparatory School of Lefke. The study was qualitative in design and the data was gathered through interviews and reflective reports. A triangulation technique was used to enhance confidence in the ensuing findings. Cross-case analysis was used to examine and identify common themes between the cases. The results showed that nonverbal communication has a pivotal role in classroom management. In EFL classes in Northern Cyprus, in order to guide teachers to use nonverbal communication before verbal communication, some seminars or workshops should be organized regarding the use of body language in classroom management to improve teachers professionally.

  12. The Class of 2011 Student Survey Report

    Science.gov (United States)

    National Association of Colleges and Employers (NJ3), 2011

    2011-01-01

    Based on responses from 20,000 college seniors nationwide, "The Class of 2011 Student Survey Report" gives you hard numbers "plus" the analysis you need to develop your college recruiting strategy and build your brand among college students. Align your recruiting strategies tactics with students' wants, needs, attitudes, and behaviors--you'll get…

  13. Higher class groups of Eichler orders

    International Nuclear Information System (INIS)

    In this paper, we prove that if A is a quaternion algebra and Λ an Eichler order in A, then the only p-torsion possible in even dimensional higher class groups Cl2n (Λ) (n ≥ 1) are for those rational primes p which lie under prime ideals of OF at which Λ are not maximal. (author)

  14. Utilization of Social Media in Marketing Classes

    Science.gov (United States)

    Allen, Charlotte

    2013-01-01

    The goal of this paper is to highlight how instructors may integrate the different social media into various marketing classes. The paper will address the major social networks, and then follow with discussions of microblogging, media sites, and social gaming. Given that there is a great deal of research highlighting the effectiveness of utilizing…

  15. p-Coloring Classes of Torus Knots

    OpenAIRE

    Breiland, Anna-Lisa; Oesper, Layla; Taalman, Laura

    2009-01-01

    We classify by elementary methods the $p$-colorability of torus knots, and prove that every $p$-colorable torus knot has exactly one nontrivial $p$-coloring class. As a consequence, we note that the two-fold branched cyclic cover of a torus knot complement has cyclic first homology group.

  16. Small Group Multitasking in Literature Classes

    Science.gov (United States)

    Baurain, Bradley

    2007-01-01

    Faced with the challenge of teaching American literature to large, multilevel classes in Vietnam, the writer developed a flexible small group framework called "multitasking". "Multitasking" sets up stable task categories which rotate among small groups from lesson to lesson. This framework enabled students to work cooperatively in a variety of…

  17. XML Schema Modeling through UML Class Diagram

    Institute of Scientific and Technical Information of China (English)

    LUJing-ping; HEYu-lin; LIShang-ping

    2004-01-01

    A three-step XML Schema modeling method is presented, namely first establishing a diagram of conceptual modeling, then transforming it to UML class diagram and finally mapping it to XML Schema. A case study of handling furniture design data is given to illustrate the detail of conversion process.

  18. Class II malocclusion occlusal severity description

    Directory of Open Access Journals (Sweden)

    Guilherme Janson

    2010-08-01

    Full Text Available OBJECTIVES: It is well known that the efficacy and the efficiency of a Class II malocclusion treatment are aspects closely related to the severity of the dental anteroposterior discrepancy. Even though, sample selection based on cephalometric variables without considering the severity of the occlusal anteroposterior discrepancy is still common in current papers. In some of them, when occlusal parameters are chosen, the severity is often neglected. The purpose of this study is to verify the importance given to the classification of Class II malocclusion, based on the criteria used for sample selection in a great number of papers published in the orthodontic journal with the highest impact factor. MATERIAL AND METHODS: A search was performed in PubMed database for full-text research papers referencing Class II malocclusion in the history of the American Journal of Orthodontics and Dentofacial Orthopedics (AJO-DO. RESULTS: A total of 359 papers were retrieved, among which only 72 (20.06% papers described the occlusal severity of the Class II malocclusion sample. In the other 287 (79.94% papers that did not specify the anteroposterior discrepancy severity, description was considered to be crucial in 159 (55.40% of them. CONCLUSIONS: Omission in describing the occlusal severity demands a cautious interpretation of 44.29% of the papers retrieved in this study.

  19. Transferring World Class Production to Developing Countries

    DEFF Research Database (Denmark)

    Bruun, Peter; Mefford, Robert Neil

    Strategic reasons for firms to transfer world-class production methods and technology to developing countries are discussed and the importance of the management aspects of technology transfer are emphasized. A five stage model of the technology transfer process which bases the choice of the...

  20. Computer Graphics Instruction in VizClass

    Science.gov (United States)

    Grimes, Douglas; Warschauer, Mark; Hutchinson, Tara; Kuester, Falko

    2005-01-01

    "VizClass" is a university classroom environment designed to offer students in computer graphics and engineering courses up-to-date visualization technologies. Three digital whiteboards and a three-dimensional stereoscopic display provide complementary display surfaces. Input devices include touchscreens on the digital whiteboards, remote…

  1. Predicting protein structure classes from function predictions

    DEFF Research Database (Denmark)

    Sommer, I.; Rahnenfuhrer, J.; de Lichtenberg, Ulrik;

    2004-01-01

    We introduce a new approach to using the information contained in sequence-to-function prediction data in order to recognize protein template classes, a critical step in predicting protein structure. The data on which our method is based comprise probabilities of functional categories; for given......-to-structure prediction methods....

  2. Incorporating Sociology into Community Service Classes

    Science.gov (United States)

    Hochschild, Thomas R., Jr.; Farley, Matthew; Chee, Vanessa

    2014-01-01

    Sociologists and instructors who teach about community service share an affinity for understanding and addressing social problems. While many studies have demonstrated the benefits of incorporating community service into sociology courses, we examine the benefits of incorporating sociological content into community service classes. The authors…

  3. 76 FR 68058 - Classes of Poultry

    Science.gov (United States)

    2011-11-03

    .... demand elasticity to be -. 43 for young chickens and - 0.62 for other chickens. Poultry Slaughter and... chicken (roaster or broiler) over the other. In addition, empirical evidence shows that price elasticity... definitions and standards for the official U.S. classes of poultry (68 FR 55902). Before publishing the...

  4. On Online Assignments in a Calculus Class

    Science.gov (United States)

    Jungic, Veselin; Kent, Deborah; Menz, Petra

    2012-01-01

    In this paper, we describe our experience with the creation and utilization of online assignments for several calculus classes at Simon Fraser University (SFU). We present our findings regarding available software by considering the needs and perspectives of the instructors, students, and administrators. We provide a list of questions that guide…

  5. Measuring the Community in Online Classes

    Science.gov (United States)

    Rubin, Beth; Fernandes, Ronald

    2013-01-01

    This paper proposes both theoretical and empirical approaches to differentiating the community of inquiry (CoI) in online classes at individual and group levels. Following the example of research on organizational climate, it assesses the strength of shared perceptions of teaching presence, social presence, and cognitive presence. The paper…

  6. Diagrammatic Reasoning with Classes and Relationships

    DEFF Research Database (Denmark)

    Nilsson, Jørgen Fischer

    2013-01-01

    We present and discuss a diagrammatic visualization and reasoning language coming about by augmenting Euler diagrams with higraphs. The diagrams serve (hierarchical as well as trans-hierarchical) classification and specification of various logical relationships between classes. The diagrams rely on...

  7. Can Gamification Be Introduced within Primary Classes?

    Science.gov (United States)

    Marín, Veronica; López, Magdalena; Maldonado, Guadalupe

    2015-01-01

    Training through gamification is everyday a more evident reality in Primary Education classes. The teachers' view about this has been modified as it is shown in the study published by aDeSe in 2012. However, does it really have place in the students' curricular development in the primary education stage? For the sake of responding to this…

  8. How to Use Body Language in Class

    Institute of Scientific and Technical Information of China (English)

    李毅

    2006-01-01

    @@ With the reform of language teaching and learning methods, teachers should use more English in class. However, with the limitation of students' vccabulary, teachers have to simplify their teaching language with the help of body language, which has perceptual and potential power, influencing the students' knowledge,emotion.character, ideology, etc.

  9. Mothers' Speech in Three Social Classes

    Science.gov (United States)

    Snow, C. E.; And Others

    1976-01-01

    Functional and linguistic aspects of the speech of Dutch-speaking mothers from three social classes to their two-year-old children were studied to test the hypothesis that simplified speech is crucial to language acquisition. Available from Plenum Publishing Corp., 227 W. 17th St., New York, NY 10011. (Author/RM)

  10. Systematic Sorting: Teacher Characteristics and Class Assignments

    Science.gov (United States)

    Kalogrides, Demetra; Loeb, Susanna; Beteille, Tara

    2013-01-01

    Although prior research has documented differences in the distribution of teacher characteristics across schools serving different student populations, few studies have examined the extent to which teacher sorting occurs within schools. This study uses data from one large urban school district and compares the class assignments of teachers who…

  11. More Middle-Class Families Choose Charters

    Science.gov (United States)

    Whitmire, Richard

    2015-01-01

    The rise in middle-class students attending charter schools is largely masked by the overall growth of charter schools: over the last five years, the number of charter schools has grown nationally from 4,690 to just over 6,000. There are now 43 communities where at least 20 percent of the students attend charters, reports the National Alliance for…

  12. Transcendental K\\"ahler Cohomology Classes

    CERN Document Server

    Popovici, Dan

    2012-01-01

    Associated with a smooth, $d$-closed $(1, 1)$-form $\\alpha$ of possibly non-rational De Rham cohomology class on a compact complex manifold $X$ is a sequence of asymptotically holomorphic complex line bundles $L_k$ on $X$ equipped with $(0, 1)$-connections $\\bar\\partial_k$ for which $\\bar\\partial_k^2\

  13. A new class of SUMO proteases

    OpenAIRE

    Gillies, Jennifer; Hochstrasser, Mark

    2012-01-01

    A new class of SUMO protease, DeSUMOylating enzyme (DeSI)—that has different substrates and localization to SENP SUMO proteases—is characterized in this issue of EMBO reports. The implications for the field are discussed here.

  14. Alternative Class Ranks Using Z-Scores

    Science.gov (United States)

    Brown, Philip H.; Van Niel, Nicholas

    2012-01-01

    Grades at US colleges and universities have increased precipitously over the last 50 years, suggesting that their signalling power has become attenuated. Moreover, average grades have risen disproportionately in some departments, implying that weak students in departments with high grades may obtain better class ranks than strong students in…

  15. Culture Teaching in English Language Classes

    Institute of Scientific and Technical Information of China (English)

    Wu Qixuan; Zhao Shuncai

    2007-01-01

    Language is closely related to culture. Language expresses and embodies cultural reality, in the meantime, culture exerts enormous influences on language. Therefore, language learning is often culture learning. The author, based on the negligence of culture teaching in English language classes, illustrates the influences of cultural knowledge on reading, translating and intercultural communicating, and proposes suggestions on culture teaching in English language teaching (ELT).

  16. Negotiations of Acknowledgement among Middle Class Residents

    DEFF Research Database (Denmark)

    Andersen, Nina Blom

    2013-01-01

    The article presents an analysis of communication processes between residents, between residents and people in the broader societal context as well as of media coverage of a fireworks disaster in a Danish suburb. It demonstrates how residents (all members of the Danish middle class) were able to...

  17. Teaching Dystopian Literature to a Consumer Class

    Science.gov (United States)

    Wilkinson, Rachel

    2010-01-01

    Many students are struggling with more depression and anxiety than ever before. These are characteristic dangers of the "consumer class"--1.7 billion people worldwide who are "characterized by diets of highly processed food, desire for bigger houses, more and bigger cars, higher levels of debt, and lifestyles devoted to the accumulation of…

  18. Hierarchical Classes Modeling of Rating Data

    Science.gov (United States)

    Van Mechelen, Iven; Lombardi, Luigi; Ceulemans, Eva

    2007-01-01

    Hierarchical classes (HICLAS) models constitute a distinct family of structural models for N-way N-mode data. All members of the family include N simultaneous and linked classifications of the elements of the N modes implied by the data; those classifications are organized in terms of hierarchical, if-then-type relations. Moreover, the models are…

  19. World class manufacturing in metallurgical enterprise

    Directory of Open Access Journals (Sweden)

    B. Gajdzik

    2013-01-01

    Full Text Available World Class Manufacturing (WCM assumes increase of efficiency of the company by elimination of all the losses, wastage and dangers of safety. In ArcelorMittal the concept of WCM is implemented in particular enterprises within the capital group. In this publication the activities conducted in some of those enterprises are described.

  20. Classroom Management Challenges in the Dance Class

    Science.gov (United States)

    Clark, Dawn

    2007-01-01

    Teaching dance can be a challenge because of the unique classroom-management situations that arise from the dynamic nature of the class content. Management is a delicate navigation of advance planning; rule setting; the establishment and implementation of daily protocols, routines, and interventions; and the teacher's own presentation. This…

  1. Decidability Classes for Mobile Agents Computing

    CERN Document Server

    Fraigniaud, Pierre

    2010-01-01

    We establish a classification of decision problems that are to be solved by mobile agents operating in unlabeled graphs, using a deterministic protocol. The classification is with respect to the ability of a team of agents to solve the problem, possibly with the aid of additional information. In particular, our focus is on studying differences between the decidability of a decision problem by agents and its verifiability when a certificate for a positive answer is provided to the agents. We show that the class MAV of mobile agents verifiable problems is much wider than the class MAD of mobile agents decidable problems. Our main result shows that there exist natural MAV-complete problems: the most difficult problems in this class, to which all problems in MAV are reducible. Our construction of a MAV-complete problem involves two main ingredients in mobile agents computability: the topology of the quotient graph and the number of operating agents. Beyond the class MAV we show that, for a single agent, three nat...

  2. Contrasting evolutionary histories of MHC class I and class II loci in grouse—Effects of selection and gene conversion

    Science.gov (United States)

    Minias, Piotr; Bateson, Zachary W; Whittingham, Linda A; Johnson, Jeff A.; Oyler-McCance, Sara J.; Dunn, Peter O

    2016-01-01

    Genes of the major histocompatibility complex (MHC) encode receptor molecules that are responsible for recognition of intracellular and extracellular pathogens (class I and class II genes, respectively) in vertebrates. Given the different roles of class I and II MHC genes, one might expect the strength of selection to differ between these two classes. Different selective pressures may also promote different rates of gene conversion at each class. Despite these predictions, surprisingly few studies have looked at differences between class I and II genes in terms of both selection and gene conversion. Here, we investigated the molecular evolution of MHC class I and II genes in five closely related species of prairie grouse (Centrocercus and Tympanuchus) that possess one class I and two class II loci. We found striking differences in the strength of balancing selection acting on MHC class I versus class II genes. More than half of the putative antigen-binding sites (ABS) of class II were under positive or episodic diversifying selection, compared with only 10% at class I. We also found that gene conversion had a stronger role in shaping the evolution of MHC class II than class I. Overall, the combination of strong positive (balancing) selection and frequent gene conversion has maintained higher diversity of MHC class II than class I in prairie grouse. This is one of the first studies clearly demonstrating that macroevolutionary mechanisms can act differently on genes involved in the immune response against intracellular and extracellular pathogens.

  3. Gender Differences in School Achievement: A Within-Class Perspective

    Science.gov (United States)

    Cahan, Sorel; Barneron, Meir; Kassim, Suhad

    2014-01-01

    Relying on the results of the achievement tests in mathematics, science, native language (Hebrew/Arabic) and English, administered to 1430 5th-grade co-educational classes in Israel, this study examines the between-class variability of the within-class mean score gender differences and its class and school correlates. The four main results of the…

  4. Single-sex Classes: Female Physics Students State Their Case.

    Science.gov (United States)

    Streitmatter, Janice

    1998-01-01

    Examines data collected from a girls-only physics class in a public coeducational high school. Interview and observation data from this class, as well as from coeducational physics classes taught by the same teacher, illustrate that the girls in the single-sex class made substantial gains in both academic achievement and in perceptions of…

  5. The Effect of Mixed-Age Classes in Sweden

    Science.gov (United States)

    Lindstrom, Elly-Ann; Lindahl, Erica

    2011-01-01

    Mixed-aged (MA) classes are a common phenomenon around the world. In Sweden, these types of classes increased rapidly during the 1980s and 1990s, despite the fact that existing empirical support for MA classes is weak. In this paper, the effect of attending an MA class during grades 4-6 on students' cognitive skills is estimated. Using a unique…

  6. A Rebuttal to Jack Niemonen's "Whither the White Working Class?"

    Science.gov (United States)

    Khanna, Nikki; Harris, Cherise A.

    2015-01-01

    Prof. Niemonen claims that the concept of white privilege is "anti-sociological" and "mask[s] complex race-class interactions." He highlights the importance of including social class in discussions of white privilege but focuses exclusively on the white working class, neglecting how race and social class also intersect for…

  7. Group Projects in Interior Design Studio Classes: Peer Feedback Benefits

    Science.gov (United States)

    Jurado, Juan A.

    2011-01-01

    Group projects have been shown to be effective for providing peer feedback in classrooms. While students in regular enrollment classes benefit from peer feedback, low-enrollment classes face many challenges. This study compares peer feedback effectiveness between two interior design studio classes with different design projects. In one class,…

  8. 25 CFR 522.12 - Revocation of class III gaming.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Revocation of class III gaming. 522.12 Section 522.12 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR APPROVAL OF CLASS II AND CLASS III ORDINANCES AND RESOLUTIONS SUBMISSION OF GAMING ORDINANCE OR RESOLUTION § 522.12 Revocation of class...

  9. 25 CFR 502.4 - Class III gaming.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Class III gaming. 502.4 Section 502.4 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS OF THIS CHAPTER § 502.4 Class III gaming. Class III gaming means all forms of gaming that are not class I gaming or...

  10. Social Class in English Language Education in Oaxaca, Mexico

    Science.gov (United States)

    López-Gopar, Mario E.; Sughrua, William

    2014-01-01

    This article explores social class in English-language education in Oaxaca, Mexico. To this end, first, we discuss social class in Mexico as related to coloniality; second, for illustration, the paper presents the authors' own social-class analysis as language educators in Oaxaca; third, we discuss how social class impacts English education…

  11. 49 CFR 174.201 - Class 2 (gases) material cylinders.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Class 2 (gases) material cylinders. 174.201... RAIL Detailed Requirements for Class 2 (Gases) Materials § 174.201 Class 2 (gases) material cylinders. (a) Except as provided in paragraphs (b) and (c) of this section, cylinders containing Class 2...

  12. Using Storytelling Strategies to Improve Student Comprehension in Online Classes

    Science.gov (United States)

    Powell, Rasby Marlene; Murray, Ottis

    2012-01-01

    Previous research shows that presenting class material in story formats can improve student learning in lecture classes. This pilot study of eight sociology classes investigates the efficacy of using storytelling as a means to improve student comprehension in online classes. Our findings show that when material is presented in story format rather…

  13. THE WORKING CLASS, THE EMERGENCE OF THE CLASS CONSCIOUSNESS AND EDUCATION

    Directory of Open Access Journals (Sweden)

    Paulino José Orso

    2011-12-01

    Full Text Available This article deals with the class society, the emergence of the working class, its recognition as such and the education. Starts with a brief discussion of the positivist and materialist conceptions of society and historical dialectics, following, discusses the tests made by the working class in its long history to win his consciousness to another. If, from ancient times we live in a class society, this period is not the consciousness of belonging to a class of workers and much less for an action based on and consistent with this membership. This achievement goes through several times and struggles, whether against the nobility and aristocracy or against the bourgeoisie, who rub shoulders with many struggles to overthrow the forces of the Old Regime. However, these struggles the working class was also realizing that if the bourgeoisie, at various times, was interested in making alliances incidental to the conquest of power, definitely had no interest in sharing it. Thus, in the successive struggles and betrayals of the bourgeoisie, the working class was learning not only not believe in the promises and illusions of his former "comrades", but also claim the right to give the direction of their lives and "their destination".

  14. Novelty Detection in MultiClass Scenarios with Incomplete Set of Class Labels

    OpenAIRE

    Vinokurov, Nomi; Weinshall, Daphna

    2016-01-01

    We address the problem of novelty detection in multiclass scenarios where some class labels are missing from the training set. Our method is based on the initial assignment of confidence values, which measure the affinity between a new test point and each known class. We first compare the values of the two top elements in this vector of confidence values. In the heart of our method lies the training of an ensemble of classifiers, each trained to discriminate known from novel classes based on ...

  15. Structural Properties of MHC Class II Ligands, Implications for the Prediction of MHC Class II Epitopes

    DEFF Research Database (Denmark)

    Jørgensen, Kasper Winther; Buus, Søren; Nielsen, Morten

    2010-01-01

    properties of MHC class II ligands. Here, we perform one such large-scale analysis. A large set of SYFPEITHI MHC class II ligands covering more than 20 different HLA-DR molecules was analyzed in terms of their secondary structure and surface exposure characteristics in the context of the native structure of...... the corresponding source protein. We demonstrated that MHC class II ligands are significantly more exposed and have significantly more coil content than other peptides in the same protein with similar predicted binding affinity. We next exploited this observation to derive an improved prediction...

  16. Dentofacial characteristics of patients with Angle Class I and Class II malocclusions

    OpenAIRE

    Rogério Lacerda dos Santos; Antônio Carlos de Oliveira Ruellas

    2012-01-01

    OBJECTIVE: The present study assessed some cephalometric measurements of the soft tissue profile in order to observe the behavior of facial convexity in patients with Class I, Class II division 1, and Class II division 2 malocclusions. METHODS: One hundred and thirty pre-treatment teleradiographs of Caucasian patients aged 10-16 years (mean age of 12.6 years) were selected for study and divided into 3 groups. The cephalometric measurements used in the present study were the following: H.SN, C...

  17. Class conflict and civil war duration the FARC insurgency

    OpenAIRE

    Akar, Mine

    2013-01-01

    This study explores the effects of class conflicts on civil war duration. Colombian civil war, the FARC insurgency, is examined from a class-based perspective. I argue that class-based civil wars last longer than non-class based civil wars such as identity conflicts because class conflicts have deeper roots embedded in the social, political, and economic aspects of the society. Through the examination of existing theories in the civil war duration literature, I propose four arguments in the c...

  18. Three-dimensional structures of the three human class I alcohol dehydrogenases

    OpenAIRE

    Niederhut, Monica S.; Gibbons, Brian J.; Perez-Miller, Samantha; Hurley, Thomas D.

    2001-01-01

    In contrast with other animal species, humans possess three distinct genes for class I alcohol dehydrogenase and show polymorphic variation in the ADH1B and ADH1C genes. The three class I alcohol dehydrogenase isoenzymes share ∼93% sequence identity but differ in their substrate specificity and their developmental expression. We report here the first three-dimensional structures for the ADH1A and ADH1C*2 gene products at 2.5 and 2.0 Å, respectively, and the structure of the ADH1B*1 gene produ...

  19. Evolution of Dopamine Receptor Genes of the D1 Class in Vertebrates

    OpenAIRE

    Yamamoto, Kei(Department of Physics, Niigata University, Niigata 950-2181, Japan); Mirabeau, Olivier; Bureau, Charlotte; Blin, Maryline; Michon-Coudouel, Sophie; Demarque, Michaël; Vernier, Philippe

    2012-01-01

    The receptors of the dopamine neurotransmitter belong to two unrelated classes named D1 and D2. For the D1 receptor class, only two subtypes are found in mammals, the D1A and D1B, receptors, whereas additional subtypes, named D1C, D1D, and D1X, have been found in other vertebrate species. Here, we analyzed molecular phylogeny, gene synteny, and gene expression pattern of the D1 receptor subtypes in a large range of vertebrate species, which leads us to propose a new view of the evolution of D...

  20. Dimensions of a class of high-dimensional homogeneous Moran sets and Moran classes

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    A class of high-dimensional homogeneous Moran sets and Moran classes are introduced and some dimensional properties are studied. The Hausdorff dimension, modified lower box-counting dimension, lower and upper box-counting dimension, and packing dimension of high-dimensional homogeneous and partial homogeneous Cantor sets are determined. Moreover, a kind of fractal E is obtained, which is not regular but with the property Dimw(Ed)=dDimw(E), where w denotes any of the dimensions mentioned above.

  1. Changes in Cranial Base Morphology in Class I and Class II Division 1 Malocclusions

    OpenAIRE

    Agarwal, Anirudh; Pandey, Harsh; Bajaj, Kamal; Pandey, Lavesh

    2013-01-01

    Introduction: The cranial base plays a key role in craniofacial growth; it helps to integrate spatially and functionally different patterns of growth in various adjoining regions of the skull such as components of the brain, the nasal and oral cavity and the pharynx. The aim of this study was to evaluate the difference in cranial base flexure between skeletal and dental Class I and Class II division 1.

  2. Lateral cephalometric diagnosis of asymmetry in Angle Class II subdivision compared to Class I and II

    OpenAIRE

    Aparecida Fernanda Meloti; Renata de Cássia Gonçalves; Ertty Silva; Lídia Parsekian Martins; Ary dos Santos-Pinto

    2014-01-01

    INTRODUCTION: Lateral cephalometric radiographs are traditionally required for orthodontic treatment, yet rarely used to assess asymmetries. OBJECTIVE: The objective of the present study was to use lateral cephalometric radiographs to identify existing skeletal and dentoalveolar morphological alterations in Class II subdivision and to compare them with the existing morphology in Class I and II relationship. MATERIAL AND METHODS: Ninety initial lateral cephalometric radiographs of male...

  3. Variance estimation for two-class and multi-class ROC analysis using operating point averaging

    Czech Academy of Sciences Publication Activity Database

    Paclík, P.; Lai, C.; Novovičová, Jana; Duin, R.P.W.

    Tampa : IEEE, 2008, s. 1-4. ISBN 978-1-4244-2174-9. [International Conference on Pattern Recognition 2008 /19./. Tampa (US), 08.12.2008-11.12.2008] Institutional research plan: CEZ:AV0Z10750506 Keywords : receiver operator characteristic analysis * classification Subject RIV: IN - Informatics, Computer Science http://library.utia.cas.cz/separaty/2008/RO/novovicova-variance estimation for two-class and multi-class roc analysis using operating point averaging.pdf

  4. ON STUDENTS’PARTICIPATION IN ENGLISH CLASSES

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    The first possible difficulty an English teacher may encounter in his or her endeavor to make Eng-lish class more communicative may be students’ reluctance to participate.But there are reasonsbehind this seeming reluctance.Based on a recent survey,the paper analyzes students’ participa-tion psychology and both the subjective and objective factors,which may affect students’ activeparticipation in class.The writer of the paper believes that getting students started is the initialstep towards active learning and fruitful teaching.It is proposed that efforts made to get studentsinvolved should focus not only on forms of activities but also on their contents,on skill integra-tion and on establishing cooperative relationships between teacher and students and among stu-dents.

  5. Young people, drinking and social class

    DEFF Research Database (Denmark)

    Kolind, Torsten

    2011-01-01

    Analytical concepts such as 'bounded consumption' or 'controlled loss of control' have been applied to characterise contemporary youth intoxication. This article argues that this kind of cultural diagnosis benefits from being related to a focus on differences in social class. It is shown that in...... people to construct social class-related identities: mainstream youngsters continually confirm their taken-for-granted normality, and mainstream breakers resist the mainstream hegemonic (school) culture which usually defies them. In conclusion, bounded consumption, corresponding with contemporary ideals...... of self-realisation, mostly seems to be a mainstream practice. For mainstream breakers unbounded intoxication practices can be observed and analysed as part of a counterculture. The study draws on five months of fieldwork and 24 qualitative focus-group interviews with pupils attending ninth grade (14...

  6. Classes of graphs with restricted interval models

    Directory of Open Access Journals (Sweden)

    Andrzej Proskurowski

    1999-12-01

    Full Text Available We introduce q-proper interval graphs as interval graphs with interval models in which no interval is properly contained in more than q other intervals, and also provide a forbidden induced subgraph characterization of this class of graphs. We initiate a graph-theoretic study of subgraphs of q-proper interval graphs with maximum clique size k+1 and give an equivalent characterization of these graphs by restricted path-decomposition. By allowing the parameter q to vary from 0 to k, we obtain a nested hierarchy of graph families, from graphs of bandwidth at most k to graphs of pathwidth at most k. Allowing both parameters to vary, we have an infinite lattice of graph classes ordered by containment.

  7. On some classes of bipartite unitary operators

    Science.gov (United States)

    Deschamps, Julien; Nechita, Ion; Pellegrini, Clément

    2016-08-01

    We investigate unitary operators acting on a tensor product space, with the property that the quantum channels they generate, via the Stinespring dilation theorem, are of a particular type, independently of the state of the ancilla system in the Stinespring relation. The types of quantum channels we consider are those of interest in quantum information theory: unitary conjugations, constant channels, unital channels, mixed unitary channels, positive partial transpose channels, and entanglement breaking channels. For some of the classes of bipartite unitary operators corresponding to the above types of channels, we provide explicit characterizations, necessary and/or sufficient conditions for membership, and we compute the dimension of the corresponding algebraic variety. Inclusions between these classes are considered, and we show that for small dimensions, many of these sets are identical.

  8. A Maximal Tractable Class of Soft Constraints

    CERN Document Server

    Cohen, D; Jeavons, P; Krokhin, A; 10.1613/jair.1400

    2011-01-01

    Many researchers in artificial intelligence are beginning to explore the use of soft constraints to express a set of (possibly conflicting) problem requirements. A soft constraint is a function defined on a collection of variables which associates some measure of desirability with each possible combination of values for those variables. However, the crucial question of the computational complexity of finding the optimal solution to a collection of soft constraints has so far received very little attention. In this paper we identify a class of soft binary constraints for which the problem of finding the optimal solution is tractable. In other words, we show that for any given set of such constraints, there exists a polynomial time algorithm to determine the assignment having the best overall combined measure of desirability. This tractable class includes many commonly-occurring soft constraints, such as 'as near as possible' or 'as soon as possible after', as well as crisp constraints such as 'greater than'. F...

  9. Congruency class effects in the Hosotani model

    International Nuclear Information System (INIS)

    We examine the Wilson loop breaking of gauge and central symmetries by determining the background gauge field which minimises the one-loop effective potential for massless Dirac fermions on manifolds of the form Rm x S1. By writing the effective potential in terms of the polylogarithm function, it is found that the algebra preserving minima are always turning points of the potential and that the positions of the global minima of the potential are independent of the dimension of the space. A condition is obtained for stability of the classical symmetric vacua with respect to radiative corrections. We find that the gauge algebra can only be broken if we have periodic fermions in a representation of the group which lies in the same congruency class as the adjoint representation. The degree of breaking of the covering group central symmetries is found to depend both on the choice of congruency class and boundary condition for the fermion fields. (orig.)

  10. Perception of classroom climate in gym classes

    Directory of Open Access Journals (Sweden)

    Vlasta Zabukovec

    2001-09-01

    Full Text Available This presentation is a part of larger study among Slovene primary and secondary students and their sports' teachers, related to their attitude to gym classes. In this part the results of perception of classroom climate among students will be presented. In the research, 1152 students were participated; they were from fifth and seventh grade from primary school and first and third grade form secondary school. The questionnaire Classroom climate in sport classes was applied (actual and preferred form, which included seven dimensions: satisfaction, competitiveness, methods, students' activity, difficulty, adequateness and personal relationship. Results confirmed the changes in perception of classroom climate; they decreased form fifth grade of primary school to third grade of secondary school. The changes were more extensive in primary school, from primary to secondary school and became stable in secondary school. The differences in perception of classroom climate between boys and girls were confirmed, too.

  11. SMA Observations of Class 0 Protostars

    DEFF Research Database (Denmark)

    Chen, Xuepeng; Arce, Héctor G.; Zhang, Qizhou;

    2013-01-01

    We present high angular resolution 1.3 mm and 850 μm dust continuum data obtained with the Submillimeter Array toward 33 Class 0 protostars in nearby clouds (distance <500 pc), which represents so far the largest survey toward protostellar binary/multiple systems. The median angular resolution in...... the survey is 2.''5, while the median linear resolution is approximately 600 AU. Compact dust continuum emission is observed from all sources in the sample. Twenty-one sources in the sample show signatures of binarity/multiplicity, with separations ranging from 50 AU to 5000 AU. The numbers of singles......, binaries, triples, and quadruples in the sample are 12, 14, 5, and 2, respectively. The derived multiplicity frequency (MF) and companion star fraction (CSF) for Class 0 protostars are 0.64 ± 0.08 and 0.91 ± 0.05, respectively, with no correction for completeness. The derived MF and CSF in this survey are...

  12. USING ENGLISH FILMS IN COLLEGE ENGLISH CLASSES

    Institute of Scientific and Technical Information of China (English)

    ZhuHanchang; ShiHongshi

    2004-01-01

    English films are valuable and rich resources for English learning and teaching in that they present colloquial English in more "realistic" contexts, an opportunity of being exposed to different native speaker voices,slang, reduced speeches, stress, accents, ana dialects, This article introauces the criteria of choosing appropriate films to promote active viewing and effective involvement of non-English majors to make the most of films as well as some practical skills of integrating English course book learning with English films in English classes. Besides, some effective means are provided for data building and video clip making in the hope of stimulating more teachers to use English movies effectively in College English classes.

  13. Stochastic blockmodels with growing number of classes

    CERN Document Server

    Choi, David S; Airoldi, Edoardo M

    2010-01-01

    We present asymptotic and finite-sample results on the use of single-membership stochastic blockmodels for the analysis of network data. We show that the fraction of misclassified network nodes converges in probability to zero under maximum likelihood fitting when the number of classes is allowed to grow as the root of the network size and the average network degree grows at least poly-logarithmically in this size. We also establish finite-sample confidence bounds on maximum-likelihood blockmodel parameter estimates from data comprising independent Bernoulli random variates; these results hold uniformly over class assignment. We provide simulations verifying the conditions sufficient for our results, and conclude by fitting a logit parameterization of a stochastic blockmodel with covariates to a network data example comprising a collection of Facebook profiles, resulting in block estimates that reveal residual structure.

  14. An Analysis on an ESL Class

    Institute of Scientific and Technical Information of China (English)

    杜岳青

    2015-01-01

    Input is the precondition of interaction and output while output promotes the input and the interaction of language,which could increase the effectiveness of input and enhance the chance of the absorption of interaction.By analyzing an ESL class,this paper gives readers a picture of how the second language(SL)learners get information,absorb and digest the information,produce language and form their language system in their SL learning.At last,it gives suggestions on how to ensure language learners have a better chance to get comprehensible input,assimilate language during interaction and output more accurate and comprehensible second language in an ESL class.

  15. Equilibria, Fixed Points, and Complexity Classes

    CERN Document Server

    Yannakakis, Mihalis

    2008-01-01

    Many models from a variety of areas involve the computation of an equilibrium or fixed point of some kind. Examples include Nash equilibria in games; market equilibria; computing optimal strategies and the values of competitive games (stochastic and other games); stable configurations of neural networks; analysing basic stochastic models for evolution like branching processes and for language like stochastic context-free grammars; and models that incorporate the basic primitives of probability and recursion like recursive Markov chains. It is not known whether these problems can be solved in polynomial time. There are certain common computational principles underlying different types of equilibria, which are captured by the complexity classes PLS, PPAD, and FIXP. Representative complete problems for these classes are respectively, pure Nash equilibria in games where they are guaranteed to exist, (mixed) Nash equilibria in 2-player normal form games, and (mixed) Nash equilibria in normal form games with 3 (or ...

  16. Universality Classes in Folding Times of Proteins

    Science.gov (United States)

    Cieplak, Marek; Hoang, Trinh Xuan

    2003-01-01

    Molecular dynamics simulations in simplified models allow one to study the scaling properties of folding times for many proteins together under a controlled setting. We consider three variants of the Go models with different contact potentials and demonstrate scaling described by power laws and no correlation with the relative contact order parameter. We demonstrate existence of at least three kinetic universality classes that are correlated with the types of structure: the α-, α-β-, and β- proteins have the scaling exponents of ∼1.7, 2.5, and 3.2, respectively. The three classes merge into one when the contact range is truncated at a reasonable value. We elucidate the role of the potential associated with the chirality of a protein. PMID:12524300

  17. Rational design of class I MHC ligands

    Science.gov (United States)

    Rognan, D.; Scapozza, L.; Folkers, G.; Daser, Angelika

    1995-04-01

    From the knowledge of the three-dimensional structure of a class I MHC protein, several non natural peptides were designed in order to either optimize the interactions of one secondary anchor amino acid with its HLA binding pocket or to substitute the non interacting part with spacer residues. All peptides were synthesized and tested for binding to the class I MHC protein in an in vitro reconstitution assay. As predicted, the non natural peptides present an enhanced binding to the HLA-B27 molecule with respect to their natural parent peptides. This study constitutes the first step towards the rational design of non peptidic MHC ligands that should be very promising tools for the selective immunotherapy of autoimmune diseases.

  18. A class of Sudan-decodable codes

    DEFF Research Database (Denmark)

    Nielsen, Rasmus Refslund

    2000-01-01

    In this article, Sudan's algorithm is modified into an efficient method to list-decode a class of codes which can be seen as a generalization of Reed-Solomon codes. The algorithm is specialized into a very efficient method for unique decoding. The code construction can be generalized based on...... algebraic-geometry codes and the decoding algorithms are generalized accordingly. Comparisons with Reed-Solomon and Hermitian codes are made....

  19. Liquidity constraints of the middle class

    OpenAIRE

    Campbell, J.R.; Hercowitz, Zvi

    2009-01-01

    Consumption of households with liquid financial assets responds much more to transitory income shocks than the permanent-income hypothesis predicts. That is, middle class households act as if they face liquidity constraints. This paper addresses this puzzling observation with a model of impatient households that face a large recurring expenditure. In spite of impatience, they save as this expenditure draws near. We call such saving made in preparation for a foreseeable event "term saving". Un...

  20. Polarity for a Class of Levy Processes

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Polar set of Markov processes is an important concept in probabilistic potential theory, but it is not easy to judge the polarity of the sets. In this paper, we give some results which can be easily used to examine the polarity of the sets when Xt belongs to a special class of Levy processes. We also give a result about polar functions of symmetric stable processes.

  1. A Survey of English Reading Outside Class

    Institute of Scientific and Technical Information of China (English)

    Peng; Yuan

    2015-01-01

    The aims of middle school English teaching areto cultivate students to acquire reading competence,which enable them to gain the information.Reading is the required method to collect information and material.This paper reports a survey on reading outside class among senior school students,by the way of questionnaires and interview,including the interests,focus,assignment of reading time,selection of reading materials,reading motives and other aspects..

  2. A Survey of English Reading Outside Class

    Institute of Scientific and Technical Information of China (English)

    Peng Yuan

    2015-01-01

    The aims of middle school English teaching are to cultivate students to acquire reading competence,which enable them to gain the information.Reading is the required method to collect information and material.This paper reports a survey on reading outside class among senior school students,by the way of questionnaires and interview,including the interests,focus,assignment of reading time,selection of reading materials,reading motives and other aspects..

  3. Interval Analysis done in Fuzzy Class Theory

    Czech Academy of Sciences Publication Activity Database

    Horčík, Rostislav

    Linz : Johannes Kepler Universität, 2008 - (Klement, E.; Rodabaugh, S.; Stout, L.). s. 59-62 [Linz Seminar on Fuzzy Set Theory /29./. 12.02.2008-16.02.2008, Linz] R&D Projects: GA AV ČR 1ET100300517 Institutional research plan: CEZ:AV0Z10300504 Keywords : fuzzy interval analysis * fuzzy number * fuzzy class theory Subject RIV: BA - General Mathematics

  4. A class of singularly perturbed evolution systems

    Directory of Open Access Journals (Sweden)

    N. U. Ahmed

    1994-01-01

    Full Text Available In this paper we study a class of evolution equations where the semigroup generators are singularly perturbed by a nonnegative real valued function of time. Sufficient conditions for existence of evolution operators and their compactness are given including continuous dependence on the perturbation. Further, for a coupled system of singularly perturbed semilinear systems in two Banach spaces, existence of periodic solutions and their stability are studied.

  5. Community College Class Devoted to Astronomical Research

    Science.gov (United States)

    Genet, R. M.; Genet, C. L.

    2002-05-01

    A class at a small community college, Central Arizona College, was dedicated to astronomical research. Although hands-on research is usually reserved for professionals or graduate students, and occasionally individual undergraduate seniors, we decided to introduce community college students to science by devoting an entire class to research. Nine students were formed into three closely cooperating teams. The class as a whole decided that all three teams would observe Cepheid stars photometrically using a robotic telescope at the Fairborn Observatory. Speaker-phone conference calls were made to Kenneth E. Kissell for help on Cepheid selection, Michael A. Seeds for instructions on the use of the Phoenix-10 robotic telescope, and Douglas S. Hall for assitance in selecting appropriate comparison and check stars. The students obtained critical references on past observations from Konkoly Observatory via airmail. They spent several long night sessions at our apartment compiling the data, making phase calculations, and creating graphs. Finally, the students wrote up their results for publication in a forthcoming special issue of the international journal on stellar photometry, the IAPPP Communication. We concluded that conducting team research is an excellent way to introduce community college students to science, that a class devoted to cooperation as opposed to competition was refreshing, and that group student conference calls with working astronomers were inspiring. A semester, however, is a rather short time to initiate and complete research projects. The students were Sally Baldwin, Cory Bushnell, Bryan Dehart, Pamela Frantz, Carl Fugate, Mike Grill, Jessica Harger, Klay Lapa, and Diane Wiseman. We are pleased to acknowledge the assistance provided by the astronomers mentioned above, James Stuckey (Campus Dean), and our Union Institute and University doctoral committee members Florence Pittman Matusky, Donald S. Hayes, and Karen S. Grove.

  6. Pensions, informality, and the emerging middle class

    OpenAIRE

    Melguizo, Angel

    2015-01-01

    A large share of the population in emerging market economies has no pension coverage, exposing them to the economic risks arising from socio-economic and individual shocks. This problem, which arises from having large informal (unregulated) sectors, affects not only poor workers, but as many as half the newly or nearly middle class in some emerging market economies. With very little social protection coverage today, these workers will also be vulnerable in the future unless tax, labor, and so...

  7. Singularity Classes of Special 2-Flags

    OpenAIRE

    Piotr Mormul

    2009-01-01

    In the paper we discuss certain classes of vector distributions in the tangent bundles to manifolds, obtained by series of applications of the so-called generalized Cartan prolongations (gCp). The classical Cartan prolongations deal with rank-2 distributions and are responsible for the appearance of the Goursat distributions. Similarly, the so-called special multi-flags are generated in the result of successive applications of gCp's. Singularities of such distributions turn out to be very ric...

  8. Facebook, adolescenti e differenze di classe

    OpenAIRE

    Micheli, M.

    2013-01-01

    La popolarità dei siti di social network tra gli adolescenti sembrerebbe suggerire che si tratti di un campo in cui l’influenza dell’origine sociale, se non scomparsa, si sia almeno livellata. Questo articolo mette invece in evidenza come la classe sociale della famiglia continui ad essere una variabile rilevante che influisce sull’uso e il significato che gli adolescenti attribuiscono ai siti di social network. Oltre a fornire una revisione della letteratura attualmente disponibile sull’...

  9. Small-Space Analogues of Valiant's Classes

    Science.gov (United States)

    Mahajan, Meena; Rao, B. V. Raghavendra

    In the uniform circuit model of computation, the width of a boolean circuit exactly characterises the “space” complexity of the computed function. Looking for a similar relationship in Valiant’s algebraic model of computation, we propose width of an arithmetic circuit as a possible measure of space. We introduce the class VL as an algebraic variant of deterministic log-space L. In the uniform setting, we show that our definition coincides with that of VPSPACE at polynomial width.

  10. Entgrenztes Wohnen : die Creative Class im Medienzeitalter

    OpenAIRE

    Hintersteininger, Sigrid

    2006-01-01

    Entgrenztes Wohnen - Die Creative Class im Medienzeitalter Zu Beginn des 21. Jahrhunderts wird der Kultur- und Lebensraum der Menschen mehr und mehr von den Informations- und Kommunikationsmedien geprägt. Mit dem zunehmenden Eindringen dieser Medien in die Lebensräume der Menschen erfährt auch das Wohnen verstärkte Aufmerksamkeit. William Mitchell und der amerikanische Soziologe und Politologe Richard Florida weisen auf eine Verknüpfung von intensiver Nutzung der neuen Informations- und K...

  11. Class 3 semaphorin in angiogenesis and lymphangiogenesis.

    Science.gov (United States)

    Bussolino, Federico; Giraudo, Enrico; Serini, Guido

    2014-01-01

    Semaphorins were originally identified as axon guidance molecules involved in the development of the neuronal system. However, accumulating evidences have clearly demonstrated that the semaphorin system is not restricted to the brain but supports functions of other organs. Here, we review the rapidly emerging functions of sempahorins and, in particular class 3 semaphorin, in vascular and lymphatic systems during the development, tumor angiogenesis and ischemic revascularization. PMID:24217603

  12. Improving Learners' Reading Skill in EFL Class

    Institute of Scientific and Technical Information of China (English)

    杨颖

    2008-01-01

    Topics around helping students to acquire the skill of reading have become increasingly popular in the discussion of foreign language teaching.In this paper,the author emphasizes the importance of improving learners'reading skill,presents the understanding of three factors concerning how to impmve learners' reading comprehension in EFL class and then introduces a 90-minute lesson plan to illustrate the statements.

  13. "Whither the Middle Class'? A Dynamic View"

    OpenAIRE

    Greg J. Duncan; Timothy M. Smeeding; Willard Rodgers

    1991-01-01

    Research using cross-sectional survey 'snapshots' of household income taken over the past quarter century reveals a growing inequality in the distribution of annual money income of households in the United States (Thurow, 1987; Levy, 1987; Levy and Michel, 1991; Michel, 1991; Karoly, 1990; Center on Budget and Policy Priorities, 1990; Easterlin, MacDonald and Macunovich, 1990), prompting some to argue that the U.S. middle class is disappearing (Phillips, 1990; Bradbury, 1986). Aggregate data ...

  14. Class, Social suffering and Health Consumerism

    OpenAIRE

    Merrild, Camilla Hoffmann; Risør, Mette Bech; Vedsted, Peter; Andersen, Rikke Sand

    2015-01-01

    In recent years an extensive social gradient in cancer outcome has attracted much attention, with late diagnosis proposed as one important reason for this. Whereas earlier research has investigated health care seeking among cancer patients, these social differences may be better understood by looking at health care seeking practices among people who are not diagnosed with cancer. Drawing on long-term ethnographic fieldwork among two different social classes in Denmark, our aim in ...

  15. Celebrity chav : fame, femininity and social class.

    OpenAIRE

    Tyler, Imogen; Bennett, Bruce

    2010-01-01

    There is nothing new about celebrity culture. It is an intrinsic feature of a world structured by mechanical reproduction. However, what has been visible over the last few years in Britain is a modulation of representations of celebrity figures in entertainment and news media through reality TV series, newspapers and gossip magazines. In this article, we argue that celebrity is an increasingly significant means by which reactionary class attitudes, allegiances and judgements are communicated....

  16. The Complexity of Identifying Large Equivalence Classes

    DEFF Research Database (Denmark)

    Skyum, Sven; Frandsen, Gudmund Skovbjerg; Miltersen, Peter Bro;

    1999-01-01

    We prove that at least 3k−4/k(2k−3)(n/2) – O(k)equivalence tests and no more than 2/k (n/2) + O(n) equivalence tests are needed in the worst case to identify the equivalence classes with at least k members in set of n elements. The upper bound is an improvement by a factor 2 compared to known res...

  17. Demographic Characteristics of World Class Jamaican Sprinters

    OpenAIRE

    Rachael Irving; Vilma Charlton; Errol Morrison; Aldeam Facey; Oral Buchanan

    2013-01-01

    The dominance of Jamaican sprinters in international meets remains largely unexplained. Proposed explanations include demographics and favorable physiological characteristics. The aim of this study was to analyze the demographic characteristics of world class Jamaican sprinters. Questionnaires administered to 120 members of the Jamaican national team and 125 controls elicited information on place of birth, language, ethnicity, and distance and method of travel to school. Athletes were divided...

  18. Universality classes in folding times of proteins

    OpenAIRE

    Cieplak, Marek; Hoang, Trinh Xuan

    2002-01-01

    Molecular dynamics simulations in simplified models allow one to study the scaling properties of folding times for many proteins together under a controlled setting. We consider three variants of the Go models with different contact potentials and demonstrate scaling described by power laws and no correlation with the relative contact order parameter. We demonstrate existence of at least three kinetic universality classes which are correlated with the types of structure: the alpha-, alpha--be...

  19. Do Students Go to Class? Should They?

    OpenAIRE

    David Romer

    1993-01-01

    Lectures and other class meetings are a primary means of instruction in almost all undergraduate courses. Yet almost everyone who has taught an undergraduate course has probably noticed that attendance at these meetings is far from perfect. There is surprisingly little systematic evidence, however, about attendance and its effects. There are three natural questions: What is the extent of absenteeism? How much, if at all, does absenteeism affect learning? Should anything be done about absentee...

  20. The second Chern class in Spinning System

    OpenAIRE

    Duan, Yishi; Fu, Libin; Liu, Xin

    1999-01-01

    Topological property in a spinning system should be directly associated with its wavefunction. A complete decomposition formula of SU(2) gauge potential in terms of spinning wavefunction is established rigorously. Based on the $\\phi $-mapping theory and this formula, one proves that the second Chern class is inherent in the spinning system. It is showed that this topological invariant is only determined by the Hopf index and Brouwer degree of the spinning wavefunction.

  1. Another Class of Perfect Nonlinear Polynomial Functions

    Directory of Open Access Journals (Sweden)

    Menglong Su

    2013-01-01

    Full Text Available Perfect nonlinear (PN functions have been an interesting subject of study for a long time and have applications in coding theory, cryptography, combinatorial designs, and so on. In this paper, the planarity of the trinomials xpk+1+ux2+vx2pk over GF(p2k are presented. This class of PN functions are all EA-equivalent to x2.

  2. Does JavaScript software embrace classes?

    OpenAIRE

    Humberto Silva, Leonardo; Ramos, Miguel; Valente, Marco Tulio; Bergel, Alexandre; Anquetil, Nicolas

    2015-01-01

    International audience JavaScript is the de facto programming language for the Web. It is used to implement mail clients, office applications, or IDEs, that can weight hundreds of thousands of lines of code. The language itself is prototype based, but to master the complexity of their application, practitioners commonly rely on some informal class abstractions. This practice has never been the target of empirical investigations in JavaScript. Yet, understanding it would be key to adequatel...

  3. Silicon carbonitrides - A novel class of materials

    OpenAIRE

    SchÖnfelder, H.; Aldinger, F.; R. Riedel

    1993-01-01

    Silicon carbonitride monoliths derived from polymer powder compacts via polymer pyrolysis represent a new class of structural ceramic materials due to the complete coalescence of the powder particles during polymer decomposition and the formation of a uniform ceramic matrix free from any grain boundaries or secondary phases. The submicron pore channel system penetrating the material can be minimized in volume by infiltration of liquid polysilazane solution or by post-HIPing so that relative d...

  4. James Hanley: modernism and the working class.

    OpenAIRE

    Fordham, John

    1997-01-01

    This thesis examines the work of James Hanley (1901-1985), a working-class ordinary seaman who became a professional writer for most of his adult life. His reputation was made originally during the 1930s when he was often identified with the emergent group of industrial-based' proletarian' realists. However, Hanley's writing radically departs from conventional notions of realism and will be shown to have closer associations with both mainstream and sub-cultural forms of modernism. Theore...

  5. Is EC class predictable from reaction mechanism?

    OpenAIRE

    Nath Neetika; Mitchell John BO

    2012-01-01

    We thank the Scottish Universities Life Sciences Alliance (SULSA) and the Scottish Overseas Research Student Awards Scheme of the Scottish Funding Council (SFC) for financial support. Background: We investigate the relationships between the EC (Enzyme Commission) class, the associated chemical reaction, and the reaction mechanism by building predictive models using Support Vector Machine (SVM), Random Forest (RF) and k-Nearest Neighbours (kNN). We consider two ways of encoding the reaction...

  6. X-Windows Socket Widget Class

    Science.gov (United States)

    Barry, Matthew R.

    2006-01-01

    The X-Windows Socket Widget Class ("Class" is used here in the object-oriented-programming sense of the word) was devised to simplify the task of implementing network connections for graphical-user-interface (GUI) computer programs. UNIX Transmission Control Protocol/Internet Protocol (TCP/IP) socket programming libraries require many method calls to configure, operate, and destroy sockets. Most X Windows GUI programs use widget sets or toolkits to facilitate management of complex objects. The widget standards facilitate construction of toolkits and application programs. The X-Windows Socket Widget Class encapsulates UNIX TCP/IP socket-management tasks within the framework of an X Windows widget. Using the widget framework, X Windows GUI programs can treat one or more network socket instances in the same manner as that of other graphical widgets, making it easier to program sockets. Wrapping ISP socket programming libraries inside a widget framework enables a programmer to treat a network interface as though it were a GUI.

  7. [Social class and health in Latin America].

    Science.gov (United States)

    Muntaner, Carles; Rocha, Katia B; Borrell, Carme; Vallebuona, Clelia; Ibáñez, Ciro; Benach, Joan; Sollar, Orielle

    2012-02-01

    This paper reviews the principal concepts of social class, occupation, and social stratification, and their contribution to the analysis of the social determinants of health (SDH), and reviews empirical studies conducted in Latin America that use employment relations as an SDH. The review focuses on studies of the relationship between health and social class based on neo-Weberian or neo-Marxist perspectives. A search of the BIREME Virtual Health Library and the SciELO database found 28 articles meeting these characteristics. This relative dearth contrasts with the profusion of papers that use these approaches written in Europe and in the United States, with a long tradition in the analysis of SDH. In this regard, the political and programmatic implications of research on social class and employment relations are different from and complementary to studies of health gradients associated with income and education. Globalization of employment relations requires the development of new concepts to explain and measure the mechanisms of action of the SDH going beyond what is strictly labor related; in particular, the importance in the current Latin American reality of the impact of informal work on health. PMID:22522881

  8. Class Wars: Initial Steps Into The Fray

    Directory of Open Access Journals (Sweden)

    Lebor, Merv

    2013-01-01

    Full Text Available This article explores the issue of preparing trainee teachers for the challenges of how to face their students’ ‘disruptive behaviour’ which sometimes marks the beginning and sets the tone for the remainder of sessions. In this paper I explore my work mentoring two trainee teachers, looking at the options available to them on entering classrooms where students displayed disruptive behaviour. There is a context of Ofsted criteria, whereby disruptive behaviour is no longer acceptable and ‘failure’ is allocated as an observation grade where ‘disruptive behaviour’ occurs. This piece offers an exploration of classroom management strategies for preparing trainee teachers who face challenging situations in Further Education (FE environments and suggests strategies for dealing with the difficulties of disruptive classes. The reason why this is vitally important is because trainee teachers in Cert Ed classes wish to discuss this issue more than any other topic. It affects their self-esteem, confidence and class interaction in delivering the curriculum.

  9. Probing Inflation, Reionization, and Neutrinos with CLASS

    Science.gov (United States)

    Marriage, Tobias; CLASS Collaboration

    2016-06-01

    We are beginning a survey to provide a robust detection and characterization of the imprint of inflationary gravitational radiation in the CMB polarization (the so-called "B modes"). The same polarization measurement will provide the ultimate CMB-based cosmic-variance-limited measurement of the optical depth to reionization. When combined with CMB temperature, lensing and Baryon Acoustic Oscillation data, the optical depth measurement will yield twofold improvements on cosmology-based estimates of the sum of the neutrino masses. To carry out the survey we have built the Cosmology Large Angular Scale Surveyor (CLASS), which is an array of millimeter-wave polarimeters sited at 5200 m in the Atacama Desert. Unique in the field of CMB polarization measurements, CLASS is especially designed to survey 70% of the sky at four frequencies (40-220 GHz) and recover the CMB polarization on all angular scales relevant to inflation and reionization. In this talk I will give an overview of CLASS and discuss progress to date.

  10. O precariado e a luta de classes

    Directory of Open Access Journals (Sweden)

    Guy Standing

    2014-05-01

    Full Text Available A economia mundial encontra‑se em plena Transformação Global, produzindo uma nova estrutura de classes a nível global. Está a surgir uma nova classe – o precariado –, que se caracteriza por incerteza e insegurança crónicas. Embora o precariado esteja ainda em constituição, com divisões no seu seio, os seus elementos encontram­‑se unidos na rejeição das velhas tradições políticas dominantes. Para se tornar uma classe transformadora, no entanto, o precariado necessita de ultrapassar o estádio de rebelião primária manifestado em 2011 e de se constituir como uma classe‑para‑si, capaz de se assumir como força de mudança. Isto implica uma luta pela redistribuição dos bens fundamentais para uma vida boa numa sociedade boa no século xxi – não os “meios de produção”, mas a segurança socioeconómica, o controlo sobre o tempo, espaços de qualidade, conhecimento (ou instrução, saber financeiro e capital financeiro.

  11. Disability, disparate impact, and class actions.

    Science.gov (United States)

    Stein, Michael Ashley; Waterstone, Michael E

    2006-12-01

    Following Title VII's enactment, group-based employment discrimination actions flourished due to disparate impact theory and the class action device. Courts recognized that subordination that defined a group's social identity was also sufficient legally to bind members together, even when relief had to be issued individually. Woven through these cases was a notion of panethnicity that united inherently unrelated groups into a common identity, for example, Asian Americans. Stringent judicial interpretation subsequently eroded both legal frameworks and it has become increasingly difficult to assert collective employment actions, even against discriminatory practices affecting an entire group. This deconstruction has immensely disadvantaged persons with disabilities. Under the Americans with Disabilities Act (ADA), individual employee claims to accommodate specific impairments, such as whether to install ramps or replace computer screens, have all but eclipsed a coherent theory of disability-based disparate impact law. Moreover, the class action device has been virtually nonexistent in disability discrimination employment cases. The absence of collective action has been especially harmful because the realm of the workplace is precisely where group-based remedies are needed most. Specifically, a crucial but overlooked issue in disability integration is the harder-to-reach embedded norms that require job and policy modifications. The Article argues that pandisability theory serves as an analogue to earlier notions of panethnicity and provides an equally compelling heuristic for determining class identity. It shows that pandisability undergirds ADA public service and public accommodation class actions in which individualized remedy assessments have been accepted as part of group-based challenges to social exclusion. The Article also demonstrates that this broader vision of collective action is consistent with the history underlying the class action device. Taking

  12. Lattices of Schunck Classes of Finite Universal Algebras

    Institute of Scientific and Technical Information of China (English)

    Wenbin Guo; K.P. Shum

    2003-01-01

    We prove that the set of all Schunck classes of Mal'cev algebras satisfying the maximum condition for subalgebras is a distributive lattice and its sublattice consisting of all Schunck classes of finite algebras is algebraic. This generalizes many results in the literature on Schunck classes. We also obtain some equivalent conditions for a class of algebras to be a Schunck class and investigate the structure of the class (algebras A |τ(A) = {A}), where τ is a subsystem functor.2000 Mathematics Subject Classification: 08A05, 08B05

  13. Identifying Clusters of Concepts in a Low Cohesive Class for Extract Class Refactoring Using Metrics Supplemented Agglomerative Clustering Technique

    CERN Document Server

    Rao, A Ananda

    2012-01-01

    Object oriented software with low cohesive classes can increase maintenance cost. Low cohesive classes are likely to be introduced into the software during initial design due to deviation from design principles and during evolution due to software deterioration. Low cohesive class performs operations that should be done by two or more classes. The low cohesive classes need to be identified and refactored using extract class refactoring to improve the cohesion. In this regard, two aspects are involved; the first one is to identify the low cohesive classes and the second one is to identify the clusters of concepts in the low cohesive classes for extract class refactoring. In this paper, we propose metrics supplemented agglomerative clustering technique for covering the above two aspects. The proposed metrics are validated using Weyuker's properties. The approach is applied successfully on two examples and on a case study.

  14. μ-Theraphotoxin-An1a

    DEFF Research Database (Denmark)

    Rates, Breno; Prates, Maura V; Verano-Braga, Thiago;

    2013-01-01

    nM) induces membrane depolarization, increases the spontaneous firing frequency and reduces spike amplitude of cockroach dorsal unpaired median (DUM) neurons. In addition, under voltage-clamp conditions, μ-TRTX-An1a (100 nM) only partially blocks voltage-dependent sodium current amplitudes in DUM...

  15. 2000 Johnston Site 1A-P

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Underwater Site 1A-P was established at Johnston Atoll by Dr. James Maragos, U.S. Fish & Wildlife Service, on June 29, 2000. With a start point (meter 0) at...

  16. 2006 Johnston Site 1A-P

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Underwater Site 1A-P was established at Johnston Atoll by Dr. James Maragos, U.S. Fish & Wildlife Service, on June 29, 2000. With a start point (meter 0) at...

  17. Sensitivity Analysis of Gas Production from Class 2 and Class 3 Hydrate Deposits

    Energy Technology Data Exchange (ETDEWEB)

    Reagan, Matthew; Moridis, George; Zhang, Keni

    2008-05-01

    Gas hydrates are solid crystalline compounds in which gas molecules are lodged within the lattices of an ice-like crystalline solid. The vast quantities of hydrocarbon gases trapped in hydrate formations in the permafrost and in deep ocean sediments may constitute a new and promising energy source. Class 2 hydrate deposits are characterized by a Hydrate-Bearing Layer (HBL) that is underlain by a saturated zone of mobile water. Class 3 hydrate deposits are characterized by an isolated Hydrate-Bearing Layer (HBL) that is not in contact with any hydrate-free zone of mobile fluids. Both classes of deposits have been shown to be good candidates for exploitation in earlier studies of gas production via vertical well designs - in this study we extend the analysis to include systems with varying porosity, anisotropy, well spacing, and the presence of permeable boundaries. For Class 2 deposits, the results show that production rate and efficiency depend strongly on formation porosity, have a mild dependence on formation anisotropy, and that tighter well spacing produces gas at higher rates over shorter time periods. For Class 3 deposits, production rates and efficiency also depend significantly on formation porosity, are impacted negatively by anisotropy, and production rates may be larger, over longer times, for well configurations that use a greater well spacing. Finally, we performed preliminary calculations to assess a worst-case scenario for permeable system boundaries, and found that the efficiency of depressurization-based production strategies are compromised by migration of fluids from outside the system.

  18. Lateral cephalometric diagnosis of asymmetry in Angle Class II subdivision compared to Class I and II

    Directory of Open Access Journals (Sweden)

    Aparecida Fernanda Meloti

    2014-08-01

    Full Text Available INTRODUCTION: Lateral cephalometric radiographs are traditionally required for orthodontic treatment, yet rarely used to assess asymmetries. OBJECTIVE: The objective of the present study was to use lateral cephalometric radiographs to identify existing skeletal and dentoalveolar morphological alterations in Class II subdivision and to compare them with the existing morphology in Class I and II relationship. MATERIAL AND METHODS: Ninety initial lateral cephalometric radiographs of male and female Brazilian children aged between 12 to 15 years old were randomly and proportionally divided into three groups: Group 1 (Class I, Group 2 (Class II and Group 3 (Class II subdivision. Analysis of lateral cephalometric radiographs included angular measurements, horizontal linear measurements and two indexes of asymmetry that were prepared for this study. RESULTS: In accordance with an Index of Dental Asymmetry (IDA, greater mandibular dental asymmetry was identified in Group 3. An Index of Mandibular Asymmetry (IMA revealed less skeletal and dental mandibular asymmetry in Group 2, greater skeletal mandibular asymmetry in Group 1, and greater mandibular dental asymmetry in Group 3. CONCLUSION: Both IDA and IMA revealed greater mandibular dental asymmetry for Group 3 in comparison to Groups 1 and 2. These results are in accordance with those found by other diagnostic methods, showing that lateral cephalometric radiography is an acceptable method to identify existing skeletal and dentoalveolar morphological alterations in malocclusions.

  19. Dyslipidemias as generating issue in Biochemistry classes

    Directory of Open Access Journals (Sweden)

    R. M. Lima

    2015-08-01

    Full Text Available The traditional didactic model is based on the transmission of the teacher's encyclopedic knowledge. In this model, the teaching of Science aims at the transmission of dominant values, regarded as absolute truths. The teacher is seen is an expert on scientific contents who transmits them to students without motivating them, and without taking into consideration their previous ideas and life experience. This model contributes to the formation of professionals who accept those values uncritically. An effective approach to break up this traditional teaching model in Biochemistry is the use of a generating issue. A Generating Issue is the starting point to the knowledge construction process which, in turn, replaces traditional models. Thus, this study aimed at developing a lesson for a 12th grade class at IF Fluminense on the following content: alcohol, carboxylic acid, ester, and esterification reaction, using dyslipidemias as the Generating Issue. To verify the value of such methodology in Biochemistry classroom, data was collected by applying a questionnaire and images with texts produced by students. In addition, they had a class based on the methodology known as Three Pedagogical Moments, proposed by Delizoicov et al. (2007. Several didactic resources designed by the authors were used, such as slide presentation, tridimensional molecular models, and a roulette game named “Bioquimicados”, based on the Facebook game “Perguntados” ("Trivia Crack". After this, students developed more grounded scientific concepts, making use of terms common in scientific language. This suggests that the use of the Generating Issue in a lesson based on problematization, and supported by a ludic activity, provided a meaningful contribution to improve the students' understanding of the scientific content. This type of non-traditional class promotes greater student motivation, resulting in meaningful learning.

  20. GOALS OF PARTICIPATION IN PHYSICAL EDUCATION CLASSES

    Directory of Open Access Journals (Sweden)

    Rahim Ramzaninezhad

    2011-07-01

    Full Text Available The importance of physical education in school life and for health points to the need to the better understands goal's participation of students in school education classes. This study was an attempt to investigate students' goals for participates in physical education (PE classes. 455 random out of 72673 students of junior and senior high schools with the age range of 11 to 19 years (M=14.67. A 28-items survey was administrated to assess (a demographics and (b Purposes for Engaging in Physical Activity (PEPAS, on a 5-point Likert scale [23]. A panel of experts (n=10 reviewed the translated from of survey and provided feedback and comments on content validity of the instrument, and 50 student participated in pilot study. The analysis of the result indicated that the Individual development (the physiological efficiency and Psychic equilibrium was rated the highest goal of participating in physical activity followed by the social interaction (the group interaction and cultural involvement and the environmental coping (the spatial orientation and object manipulation. One-way Tukeys' post hoc comparison revealed significant difference between groups of subject differentiated on the basis gender age, Junior/senior high school, physical activity out of school, school team member ships, and physical activity on summer & holidays as Independent factors. The multivariate effect of these factors on some of the student's purpose was significant. The unvaried analyses showed that these factors had a significant effect on some of goals. These findings indicate the importance of ranking of students' purposes for engaging in PE classes. It is also necessary that these goals to be considered by the parents & teachers point of view.

  1. The Association of HLA-Class I and Class II with Hodgkin’s Lymphoma in Iranian Patients

    OpenAIRE

    Arezou Sayad; Mohammad Taghi Akbari; Mahshid Mehdizadeh; Abolfazl Movafagh; Abbas Hajifathali

    2014-01-01

    The Hodgkin's lymphoma disease (HD) is a common malignant neoplasm with germinal centre B-cell origin. It has been suggested that the HLA class I and class II regions have susceptibility effects on HD. In different ethnic groups, different HLA class I and class II alleles affect HD. As a result, there is no consensus which of the different HLA alleles confers susceptibility to HD. In this study, we aimed to ascertain the role of HLA class I and class II alleles in association with Hodgkin's l...

  2. Social-Class Differences in Consumer Choices: Working-Class Individuals Are More Sensitive to Choices of Others Than Middle-Class Individuals.

    Science.gov (United States)

    Na, Jinkyung; McDonough, Ian M; Chan, Micaela Y; Park, Denise C

    2016-04-01

    The present research shows that, when making choices, working-class Americans are more affected by others' opinions than middle-class Americans due to differences in independent versus interdependent self-construal. Experiment 1 revealed that when working-class Americans made decisions to buy products, they were more influenced by the choices of others than middle-class Americans. In contrast, middle-class Americans were more likely to misremember others' choices to be consistent with their own choices. In other words, working-class Americans adjusted their choices to the preference of others, whereas middle-class Americans distorted others' preferences to fit their choices. Supporting our prediction that this social-class effect is closely linked to the independent versus interdependent self-construal, we showed that the differences in self-construal across cultures qualified the social-class effects on choices (Experiment 2). Moreover, when we experimentally manipulated self-construal in Experiment 3, we found that it mediated the corresponding changes in choices regardless of social class. PMID:26984010

  3. Increasing the number of thyroid lesions classes in microarray analysis improves the relevance of diagnostic markers.

    Directory of Open Access Journals (Sweden)

    Jean-Fred Fontaine

    Full Text Available BACKGROUND: Genetic markers for thyroid cancers identified by microarray analysis have offered limited predictive accuracy so far because of the few classes of thyroid lesions usually taken into account. To improve diagnostic relevance, we have simultaneously analyzed microarray data from six public datasets covering a total of 347 thyroid tissue samples representing 12 histological classes of follicular lesions and normal thyroid tissue. Our own dataset, containing about half the thyroid tissue samples, included all categories of thyroid lesions. METHODOLOGY/PRINCIPAL FINDINGS: Classifier predictions were strongly affected by similarities between classes and by the number of classes in the training sets. In each dataset, sample prediction was improved by separating the samples into three groups according to class similarities. The cross-validation of differential genes revealed four clusters with functional enrichments. The analysis of six of these genes (APOD, APOE, CLGN, CRABP1, SDHA and TIMP1 in 49 new samples showed consistent gene and protein profiles with the class similarities observed. Focusing on four subclasses of follicular tumor, we explored the diagnostic potential of 12 selected markers (CASP10, CDH16, CLGN, CRABP1, HMGB2, ALPL2, ADAMTS2, CABIN1, ALDH1A3, USP13, NR2F2, KRTHB5 by real-time quantitative RT-PCR on 32 other new samples. The gene expression profiles of follicular tumors were examined with reference to the mutational status of the Pax8-PPARgamma, TSHR, GNAS and NRAS genes. CONCLUSION/SIGNIFICANCE: We show that diagnostic tools defined on the basis of microarray data are more relevant when a large number of samples and tissue classes are used. Taking into account the relationships between the thyroid tumor pathologies, together with the main biological functions and pathways involved, improved the diagnostic accuracy of the samples. Our approach was particularly relevant for the classification of microfollicular adenomas.

  4. Determination of the Universality Class of Gadolinium

    International Nuclear Information System (INIS)

    We resolve a long-standing puzzle for the static and dynamic critical behavior of gadolinium by a combined theoretical and experimental investigation. It is shown that the spin dynamics of a ferromagnet with hcp lattice structure and a spin-spin interaction given by both exchange and dipole-dipole interaction belongs to a new dynamic universality class, model J* . Comparing results from mode coupling theory with results from three different hyperfine interaction probes we find quantitative agreement. copyright 1997 The American Physical Society

  5. Soapbox: Class matters in parenting interventions.

    Science.gov (United States)

    Zilberstein, Karen

    2016-07-01

    Class and income level influence parenting styles and values, yet are rarely discussed in treatment approaches and parenting interventions with families. In this soapbox article, I argue that discrepancies in outcome, retention, and participation could be fruitfully addressed through a fuller understanding of the needs, realities, and parenting goals of families struggling with financial disadvantage. I compare and contrast ethnographic studies of parenting in low socioeconomic environments with the types of strategies and interventions commonly advanced in parent training programs and suggest that clinicians must become more aware of the cultural and socioeconomic overtones of those interventions in determining whether, how, and when to use them with families. PMID:26888155

  6. Special cohomology classes for modular Galois representations

    CERN Document Server

    Howard, Benjamin

    2012-01-01

    Building on ideas of Vatsal, Cornut proved a conjecture of Mazur asserting the generic nonvanishing of Heegner points on an elliptic curve E as one ascends the anticyclotomic Z_p-extension of a quadratic imaginary extension K/Q. In the present article Cornut's result is extended by replacing the elliptic curve E with the Galois cohomology of Deligne's 2-dimensional l-adic representation attached to a modular form of weight 2k>2, and replacing the family of Heegner points with an analogous family of special cohomology classes.

  7. Renverser la classe inversée

    OpenAIRE

    Nagels, Marc

    2015-01-01

    Pédagogie universitaire Cette année, j'ai vécu une expérience renversante de formation. Plus fort encore que la classe inversée, j'ai renversé totalement mon enseignement à distance consacré à l'initiation à la psychologie cognitive pour les auditeurs du CNAM de Bretagne. Le slogan du cours était « un élève, cinquante professeurs ». Compte rendu à trois voix…

  8. THttpServer class in ROOT

    Science.gov (United States)

    Adamczewski-Musch, Joern; Linev, Sergey

    2015-12-01

    The new THttpServer class in ROOT implements HTTP server for arbitrary ROOT applications. It is based on Civetweb embeddable HTTP server and provides direct access to all objects registered for the server. Objects data could be provided in different formats: binary, XML, GIF/PNG, and JSON. A generic user interface for THttpServer has been implemented with HTML/JavaScript based on JavaScript ROOT development. With any modern web browser one could list, display, and monitor objects available on the server. THttpServer is used in Go4 framework to provide HTTP interface to the online analysis.

  9. Topology in Fuzzy Class Theory: Basic Notions

    Czech Academy of Sciences Publication Activity Database

    Běhounek, Libor; Kroupa, Tomáš

    Berlin : Springer, 2007 - (Melin, P.; Castillo, O.; Aguilar, L.; Kacprzyk, J.; Pedrycz, W.), s. 513-522 ISBN 978-3-540-72917-4. - (Lecture Notes in Artificial Intelligence. 4529). [IFSA 2007. International Fuzzy Systems Association World Congress /12./. Cancun (MX), 18.06.2007-21.06.2007] R&D Projects: GA AV ČR KJB100300502; GA MŠk 1M0572 Institutional research plan: CEZ:AV0Z10300504; CEZ:AV0Z10750506 Keywords : fuzzy topology * fuzzy class theory Subject RIV: BA - General Mathematics

  10. PRE-LISTENING METHODS IN LISTENING CLASS

    Institute of Scientific and Technical Information of China (English)

    ZhangYijun; WangQingjiang

    2004-01-01

    At it is often the case, listening to English is not easy for English students and it is more difficult for Non-English major students. Many students have associated listening courses with pain and boredom and often complain that they benefit little from listening lessons. So, it is necessary for English teachers to realize the importance of how to make listening class more interesting and to know how to motivate students so that they can make progress in listening comprehension. Some practical and interesting teaching methods are discussed.

  11. On a Class of Generalized Sampling Functions

    Institute of Scientific and Technical Information of China (English)

    Yi Wang

    2014-01-01

    In this note, we discuss a class of so-called generalized sampling functions. These functions are defined to be the inverse Fourier transform of a family of piece-wise constant functions that are either square integrable or Lebegue integrable on the real number line. They are in fact the generalization of the classic sinc function. Two approaches of constructing the generalized sampling functions are reviewed. Their properties such as cardinality, orthogonality, and decaying properties are discussed. The interactions of those functions and Hilbert transformer are also discussed.

  12. Transferring World Class Production to Developing Countries

    DEFF Research Database (Denmark)

    Bruun, Peter; Mefford, Robert Neil

    1998-01-01

    Strategic reasons for firms to transfer world-class production methods and technology to developing countries are discussed and the importance of the management aspects of technology transfer are emphasized. A five stage model of the technology transfer process which bases the choice of the...... production process on the strategic objectives for the plant is developed. This is followed by the selection of the type of production system and the operational methods which will support it. The final stage of the model concerns the human resource policies neede to implement the operational decisions. The...

  13. Students’ Weakness Detective in Traditional Class

    Directory of Open Access Journals (Sweden)

    Fatimah Altuhaifa

    2016-10-01

    Full Text Available In Artificial Intelligent in Education in learning contexts and domains, the traditional classroom is tough to find students’ weakness during lecture due to the student’s number and because the instruction is busy with explaining the lesson. According to that, choosing teaching style that can improve student talent or skills to performs better in their classes or professional life would not be an easy task. This system is going to detect the average of students’ weakness and find either a solution for this or instruction a style that can increase students’ ability and skills by filtering the collection data, understanding the problem. After that, it provides a teaching style.

  14. ATTITUDE SCALE DEVELOPMENT FOR VISUAL ARTS CLASS

    OpenAIRE

    ASLANTAŞ, SELMA

    2014-01-01

    The aim of this study is to develop a scale, to be used in primary school fourth grade Visual Arts Class. Our study group consists of 174 students, randomly selected from two different primary school in Ankara during 2009-2010 spring semester. An item pool of 3 items has been prepared, based on literature search and expert views. In order to determine the structural validity of the scale, exploratory and confirmatory factor analyses have been performed, through SPSS 20 programme and LISREL pr...

  15. Teaching Style and the College Writing Class

    Directory of Open Access Journals (Sweden)

    St. Rose, Marjorie

    1997-01-01

    Full Text Available This review questions the efficiency of the lecture method with particular reference to the teaching of English at the College of The Bahamas. Research studies and articles about current practice in college writing suggest that while the lecture method remains useful in subject areas dominated by transfer of large amounts of factual information, teaching methods in the English language arts have moved from product to process pedagogy, with a corresponding change from didactic to cooperative styles of teaching and learning. The writer recommends that college English classes utilize cooperative strategies.

  16. Bolstering the U.S.Middle Class

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Making every attempt to boost the sluggish U.S.economy, U.S.President Barack Obama has pledged incentive programs including tax cuts for the middle class that have "for generations,made our economy the envy of the world." But the program may not be a panacea as income inequality in the United States becomes entrenched.Zhang Monan,a researcher with the State Information Center,discussed this issue in an article recently published in the China Securities Journal.Edited excerpts follow.

  17. DYNAMICS IN A CLASS OF NEURON MODELS

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    In this paper, we investigate the dynamics in a class of discrete-time neuron mod-els. The neuron model we discussed, defined by such periodic input-output mapping as a sinusoidal function, has a remarkably larger memory capacity than the conven-tional association system with the monotonous function. Our results show that the orbit of the model takes a conventional bifurcation route, from stable equilibrium, to periodicity, even to chaotic region. And the theoretical analysis is verified by numerical simula...

  18. DYNAMICS IN A CLASS OF NEURON MODELS

    Institute of Scientific and Technical Information of China (English)

    Wang Junping; Ruan Jiong

    2009-01-01

    In this paper, we investigate the dynamics in a class of discrete-time neuron mo-dels. The neuron model we discussed, defined by such periodic input-output mapping as a sinusoidal function, has a remarkably larger memory capacity than the conven-tional association system with the monotonous function. Our results show that the orbit of the model takes a conventional bifurcation route, from stable equilibrium, to periodicity, even to chaotic region. And the theoretical analysis is verified by numerical simulations.

  19. A FESA Class Control Flow graph generator

    CERN Document Server

    Iliadi, Maria

    2015-01-01

    This report documents the work that was done during a summer student internship in the CERN BE-BI-SW group in the summer of 2015. The project proposal was to improve an existing tool for generating flowcharts from the design of a class and then create a GUI for the tool. The end result of the project is the improvement of the tool, so that the developer can have an overall image of the class’s design. Also, the GUI is functional at its current state and it can be extended with further work in order to be more user-friendly and offer more options to the user.

  20. Apo-ghrelin receptor (apo-GHSR1a Regulates Dopamine Signaling in the Brain

    Directory of Open Access Journals (Sweden)

    Andras eKern

    2014-08-01

    Full Text Available The orexigenic peptide hormone ghrelin is synthesized in the stomach and its receptor growth hormone secretagogue receptor (GHSR1a is expressed mainly in the central nervous system (CNS. In this review we confine our discussion to the physiological role of GHSR1a in the brain. Paradoxically, despite broad expression of GHSR1a in the CNS, other than trace amounts in the hypothalamus, ghrelin is undetectable in the brain. In our efforts to elucidate the function of the ligand-free ghrelin receptor (apo-GHSR1a we identified subsets of neurons that co-express GHSR1a and dopamine receptors. In this review we focus on interactions between apo-GHSR1a and dopamine-2 receptor (DRD2 and formation of GHSR1a:DRD2 heteromers in hypothalamic neurons that regulate appetite, and discuss implications for the treatment of Prader-Willi syndrome. GHSR1a antagonists of distinct chemical structures, a quinazolinone and a triazole, respectively enhance and inhibit dopamine signaling through GHSR1a:DRD2 heteromers by an allosteric mechanism. This finding illustrates a potential strategy for designing the next generation of drugs for treating eating disorders as well as psychiatric disorders caused by abnormal dopamine signaling. Treatment with a GHSR1a antagonist that enhances dopamine/DRD2 activity in GHSR1a:DRD2 expressing hypothalamic neurons has the potential to inhibit the uncontrollable hyperphagia associated with Prader-Willi syndrome. DRD2 antagonists are prescribed for treating schizophrenia, but these block dopamine signaling in all DRD2 expressing neurons and are associated with adverse side effects, including enhanced appetite and excessive weight gain. A GHSR1a antagonist of structural class that allosterically blocks dopamine/DRD2 action in GHSR1a:DRD2 expressing neurons would have no effect on neurons expressing DRD2 alone; therefore, the side effects of DRD2 antagonists would potentially be reduced thereby enhancing patient compliance.

  1. Suggestopedia, Sophrology and the Traditional Foreign Language Class.

    Science.gov (United States)

    Bancroft, W. Jane

    1982-01-01

    Describes suggestopedia and sophrology techniques and shows how to apply them within the limitations of the traditional foreign language classroom. Cites beginning French classes at Scarborough College as an example of these techniques improving class atmosphere and student motivation. (EKN)

  2. Postgraduates’ Attitudes towards Group Works in Oral English Class

    Institute of Scientific and Technical Information of China (English)

    毕思迪

    2016-01-01

    This study investigated four postgraduates’ attitudes towards group work in oral English class in Tianjin Foreign Studies University. Two sources of data were collected, including interviews and class observations.

  3. Class, Gender, and Mobility: Unraveling the "Tangled Things."

    Science.gov (United States)

    Cookson, Peter W., Jr.

    1990-01-01

    Reviews Sara Delamont's "Knowledgeable Women: Structuralism and the Reproduction of Elites" (1989), a feminist examination of the education of elite women which provides many insights into how gender and class operate within the dominant classes. (DM)

  4. CONSTRUCTION OF A NEW CLASS OF ORTHOGONAL ARRAYS

    Institute of Scientific and Technical Information of China (English)

    Shanqi PANG

    2007-01-01

    By using the generalized Hadamard product, difference matrix and projection matrices, we present a class of orthogonal projection matrices and related orthogonal arrays of strength two. A new class of orthogonal arrays are constructed.

  5. US Forest Service Watershed Condition Class and Assessment Status 2011

    Data.gov (United States)

    US Forest Service, Department of Agriculture — The map contains the Watershed Condition Class and assessment status for the assessment year of 2011. The layer is symbolized by the Watershed Condition Class for...

  6. Use of a Concentration Game for Environmental Chemistry Class Review

    Science.gov (United States)

    Nowosielski, Danica A.

    2007-01-01

    The concentration game can be used as a complete class or a portion of it to help reinforce the material being presented or for review sessions. An environmental chemistry class review is presented with the use of the concentration game.

  7. 25 CFR 502.3 - Class II gaming.

    Science.gov (United States)

    2010-04-01

    ....3 Class II gaming. Class II gaming means: (a) Bingo or lotto (whether or not electronic, computer... pattern on such cards; (b) If played in the same location as bingo or lotto, pull-tabs, punch boards,...

  8. Class and Politics in Denmark: Are Both Old and New Politics Structured by Class?

    DEFF Research Database (Denmark)

    Harrits, Gitte Sommer; Prieur, Annick; Rosenlund, Lennart;

    2010-01-01

    The trend within studies of voting and political attitudes has been to give less attention to class as a structuring dimension and more to post-material values. The basic argument of this article is that this is a false opposition: The adherence to different sets of values is related to social...... attitudes are here subjected to multiple correspondence analysis (MCA), which reveals a pattern of attitudes that is highly structured by both the old and the new dimensions of politics. Up to this point the results converge with the state of the art. However, the methodology utilized (MCA) allows to link...... the constructed space of attitudes to a set of indicators based on a two-dimensional conception of social class. On the basis of this analysis the article concludes that the political landscape appears as highly structured by the two principles of social differentiation from Bourdieu’s class model...

  9. How "healthful" are aerobics classes? Exploring the health and wellness messages in aerobics classes for women.

    Science.gov (United States)

    D'Abundo, Michelle Lee

    2007-01-01

    The purpose of this study was to explore the health messages communicated by aerobics instructors in aerobics classes for women. A theoretical framework influenced by adult learning theory and feminist pedagogy was used in this qualitative study. Over a 3-month period, the practices of five aerobics instructors working at one nonprofit fitness center and one wellness facility were explored. The methods of data collection were one interview with each aerobics instructor and 14 site visits to conduct participant observations and to retrieve of documents. Despite the nonprofit and wellness-based environment of the exercise facilities in this research, there was still an overemphasis on the physical aspect of aerobics classes. Therefore, the potential wellness-related benefits of aerobics classes for women, especially in environments that identified themselves as promoting wellness, were not fully realized. PMID:17148107

  10. Is social class standardisation appropriate in occupational studies?

    OpenAIRE

    Brisson, C; Loomis, D; Pearce, N

    1987-01-01

    Social class standardisation has been proposed as a method for separating the effects of occupation and "social" or "lifestyle" factors in epidemiological studies, by comparing workers in a particular occupation with other workers in the same social class. The validity of this method rests upon two assumptions: (1) that social factors have the same effect in all occupational groups in the same social class, and (2) that other workers in the same social class as the workers being studied are f...

  11. Archform Comparisons between Skeletal Class II and III Malocclusions

    OpenAIRE

    Zou, Wei; Wu, Jiaqi; Jiang, JiuHui; Xu, Tianmin; Li, CuiYing

    2014-01-01

    The purpose of this cross-sectional research was to explore the relationship of the mandibular dental and basal bone archforms between severe Skeletal Class II (SC2) and Skeletal Class III (SC3) malocclusions. We also compared intercanine and intermolar widths in these two malocclusion types. Thirty-three virtual pretreatment mandibular models (Skeletal Class III group) and Thirty-five Skeletal Class II group pretreatment models were created with a laser scanning system. FA (the midpoint of t...

  12. A modified BRST approach for Hamiltonians with second class constraints

    International Nuclear Information System (INIS)

    A BRST approach for a dynamical system with second class constraints based on intermediate first class ones is analyzed in a simple case. From it, a very direct scheme involving only the original constraints is derived. By generalizing the later, a modified BRST formalism is stated: it avoids any dimensional reduction or first class intermediate algebra, and is applicable to an arbitrary second class algebra. (Author)

  13. Nobility and Stupidity: Modeling the Evolution of Class Endogamy

    OpenAIRE

    Belding, Theodore C.

    2004-01-01

    Class endogamy is a phenomenon in which nobles only marry other nobles and commoners only marry other commoners. The origin of class endogamy, and of social stratification in general, is a major open question in archaeology. This paper implements a verbal model proposed by Marcus and Flannery as a class of agent-based computer models by generalizing and simplifying a mathematical model of marriage markets developed by Burdett and Coles. One force that can produce class endogamy occurs if agen...

  14. Moving with Ease: Feldenkrais Method Classes for People with Osteoarthritis

    OpenAIRE

    Robert Webb; Luis Eduardo Cofré Lizama; Galea, Mary P.

    2013-01-01

    Objective. To investigate the effects of Feldenkrais Method classes on gait, balance, function, and pain in people with osteoarthritis. Design. Prospective study with pre-/postmeasures. Setting. Community. Participants. Convenience sample of 15 community-dwelling adults with osteoarthritis (mean age 67 years) attending Feldenkrais Method classes. Intervention. Series of Feldenkrais Method classes, two classes/week for 30 weeks. Main outcome measures: Western Ontario and McMaster Universities ...

  15. The rise of middle class in rural China

    OpenAIRE

    Zhang Yuan; Guanghua Wan; Niny Khor

    2012-01-01

    Purpose – Using official and household survey data, the purpose of this paper is to analyze the size of middle class in rural China, its trend and geographical distribution. Determinants or drivers of changes in the size of middle class are explored. Design/methodology/approach – An absolute definition of middle class, adjusted by rural purchasing power parity (PPP) and spatial price index, is employed to measure the size and geographic distribution of rural middle class in 1988, 1995, 2002, ...

  16. Determinants of Student Performance in an Undergraduate Financial Accounting Class

    OpenAIRE

    Harrington, Donna Ramirez; Kulasekera, Kumuduni; Bates, Rick; Bredahl, Maury E.

    2006-01-01

    This study investigates the effects of class size, high school accounting, aptitude and attitude on learning , measured by the difference between post-test and pre-test scores, in an undergraduate financial accounting class, after controlling for students' major and semester level. Statistical analysis showed that scores of students in small classes improved by 48%, while scores of students in the large classes improved by 6% percent, implying a decline in learning by 88% by shifting to large...

  17. Analysis of Asset Classes Through the Business Cycle

    OpenAIRE

    Audrius Dzikevičius; Jaroslav Vetrov

    2012-01-01

    This study was driven by the dissimilar performance characteristics displayed by asset classes over the business cycle. The authors aim to explore assets classes on the grounds of a scientific literature review and a statistical analysis. Business cycles are divided into four stages to explore broad movements in returns of asset classes and a possible existence of asymmetrical effects of determinants within stages. Six main asset classes were analysed: US stocks, EAFE stocks, Bonds, Gold, Rea...

  18. Spectral energy distribution analysis of class I and class II FU Orionis stars

    Energy Technology Data Exchange (ETDEWEB)

    Gramajo, Luciana V.; Gómez, Mercedes [Observatorio Astronómico, Universidad Nacional de Córdoba, Argentina, Laprida 854, 5000 Córdoba (Argentina); Rodón, Javier A., E-mail: luciana@oac.uncor.edu, E-mail: mercedes@oac.uncor.edu, E-mail: jrodon@eso.org [European Southern Observatory, Alonso de Córdova 3107, Vitacura, Casilla 19001, Santiago 19 (Chile)

    2014-06-01

    FU Orionis stars (FUors) are eruptive pre-main sequence objects thought to represent quasi-periodic or recurring stages of enhanced accretion during the low-mass star-forming process. We characterize the sample of known and candidate FUors in a homogeneous and consistent way, deriving stellar and circumstellar parameters for each object. We emphasize the analysis in those parameters that are supposed to vary during the FUor stage. We modeled the spectral energy distributions of 24 of the 26 currently known FUors, using the radiative transfer code of Whitney et al. We compare our models with those obtained by Robitaille et al. for Taurus class II and I sources in quiescence periods by calculating the cumulative distribution of the different parameters. FUors have more massive disks: we find that ∼80% of the disks in FUors are more massive than any Taurus class II and I sources in the sample. Median values for the disk mass accretion rates are ∼10{sup –7} M {sub ☉} yr{sup –1} versus ∼10{sup –5} M {sub ☉} yr{sup –1} for standard young stellar objects (YSOs) and FUors, respectively. While the distributions of envelope mass accretion rates for class I FUors and standard class I objects are similar, FUors, on average, have higher envelope mass accretion rates than standard class II and class I sources. Most FUors (∼70%) have envelope mass accretion rates above 10{sup –7} M {sub ☉} yr{sup –1}. In contrast, 60% of the classical YSO sample has an accretion rate below this value. Our results support the current scenario in which changes experimented by the circumstellar disk explain the observed properties of these stars. However, the increase in the disk mass accretion rate is smaller than theoretically predicted, although in good agreement with previous determinations.

  19. Yilmaz Theory of SNe 1a Redshift

    OpenAIRE

    Robertson, Stanley L.

    2015-01-01

    A redshift-luminosity distance relation in excellent agreement with observations is calculated here for SNe 1a using the Yilmaz gravitational theory. In contrast to the current conventional explanation based on general relativity, the Yilmaz theory does not require a cosmological constant term that implies the existence of "dark energy". The Yilmaz theory requires only one parameter; a mean mass-energy density of the cosmos. The required value is essentially the same as the critical density f...

  20. Is the class of all fuzzy rings a fuzzy HSP-class?

    Directory of Open Access Journals (Sweden)

    Nistala V. E. S. Murthy

    2003-09-01

    Full Text Available The aim of this paper is to generalize, the notion of fuzzy subring of a crisp ring to that of a fuzzy ring and the notion of crisp homomorphism between crisp rings with fuzzy direct image and fuzzy inverse image to that of a fuzzy homomorphism between fuzzy rings with truth values in different complete lattices, with fuzzy direct and inverse images, in such a way that the class of all fuzzy rings is in fact a fuzzy HSP-Class. In the process several elementary but important properties that naturally extended, are recorded including Correspondence and Isomorphism Theorems.

  1. Transcutaneous RF-Powered Implantable Minipump Driven by a Class-E Transmitter

    OpenAIRE

    Moore, William H.; Holschneider, Daniel P.; Givrad, Tina K.; Maarek, Jean-Michel I.

    2006-01-01

    We describe the design and testing of an inductive coupling system used to power an implantable minipump for applications in ambulating rats. A 2 MHz class-E oscillator driver powered a coil transmitter wound around a 33-cm-diameter rat cage. A receiver coil, a filtered rectifier, and a voltage-sensitive switch powered the implant. The implant DC current at the center of the primary coil (5.1 V) exceeded the level required to activate the solenoid valve in the pump. The variations of the impl...

  2. A C++ class library for telescope pointing

    Science.gov (United States)

    Terrett, David L.

    2006-06-01

    tpk is a C++ class library, layered on TCSpk and slalib that implements virtual telescope objects for generating mount and rotator position (and optionally, velocity and acceleration) demands, predicting the position of guide probes etc. in the focal plane and tip and tilt for steerable optics. These objects allocate and manage storage for the kernel context in a thread safe manner enabling a pointing kernel for a specific telescope configuration to be constructed simply by creating the necessary objects and calling their "fast", "medium" and "slow" update methods at the appropriate rates. Additional facilities include: Tracking of solar system objects using orbital elements as tabulated by the Minor Planet Center, the JPL Horizons system and the Astronomical Almanac or the for the major planets, built-in ephemeredes due to Chapront and Francou - Management of pointing models including the logging of pointing test data capable of being read into TPOINT, catalogues of pointing reference stars and pointing adjustments from handsets and guiders including the necessary digital filters - Generation of world coordinate system mappings and FITS keywords for instruments. The library can be tailored for a particular operating environment by replacing the mutex and clock classes. For "off-line" or otherwise non time-critical application the existing Posix and Windows implementations can be used.

  3. On the Structure of Valiant's Complexity Classes

    Directory of Open Access Journals (Sweden)

    Peter Bürgisser

    1999-12-01

    Full Text Available In Valiant developed an algebraic analogue of the theory of NP-completeness for computations of polynomials over a field. We further develop this theory in the spirit of structural complexity and obtain analogues of well-known results by Baker, Gill, and Solovay, Ladner, and Schöning. We show that if Valiant's hypothesis is true, then there is a p-definable family, which is neither p-computable nor VNP-complete. More generally, we define the posets of p-degrees and c-degrees of p-definable families and prove that any countable poset can be embedded in either of them, provided Valiant's hypothesis is true. Moreover, we establish the existence of minimal pairs for VPin VNP. Over finite fields, we give a specific example of a family of polynomials which is neither VNP-complete nor p-computable, provided the polynomial hierarchy does not collapse. We define relativized complexity classes VP h and VNP h and construct complete families in these classes. Moreover, we prove that there is a p-family h satisfying VP h = VNP h.

  4. HUMANISTIC STRATEGIES IN THE EFL SPEAKING CLASS

    Directory of Open Access Journals (Sweden)

    Josefa J. Mardijono

    2001-01-01

    Full Text Available This paper focuses on the humanistic strategies woven into the EFL speaking class activities. The speaking class, which the writer used for her study, is the highest level of speaking course offered in the curriculum of the English Department of Petra Christian University, to develop students' English speaking skills, particularly in public speaking. The humanistic strategies are based on the assumption that a "supportive and co-operative group atmosphere" ((Hadfield, 1995, p.15 will enhance learning to bring out the best of the students. The primary aims are to help the students, through active participation, to develop more positive feelings about themselves and their classmates, to co-operate and support each other to grow and excel at their speech performance. Based on the students' evaluation and the teacher's observation of the students' public speech performance and their academic achievement, it can be concluded that the humanistic strategies have created a co-operative and supportive group atmosphere and has given positive effects on the students' speech performance. This is also a rewarding experience for the teacher.

  5. Stable magnetic universality classes for T->0

    International Nuclear Information System (INIS)

    In previous experimental investigations we have observed that a single power function of absolute temperature according to 1-mS(T)=cxTε describes the deviations of the magnetic order parameter, mS(T), from saturation of unity at T=0 better than classical power series expansions if an appropriate empirical exponent ε is chosen. Six universality classes represented by different power functions could be established. It is evident that the Tε function holds exactly only if the pre-factor c is a constant. We present experimental evidence that the pre-factor c assumes only discrete values meaning that the universal cxTε power function is well stabilized against various weakly temperature-dependent non-relevant parameters. Discrete changes of either c or ε which we have called amplitude crossover and exponent crossover, respectively, occur only after changes of the magnetic interactions beyond some threshold value. The thermodynamics of the order parameter can therefore be considered as quantized. In particular, cubic magnets with a pure spin moment belong per definition to the isotropic three-dimensional (3D) universality class. As a consequence, ε is constant and only amplitude crossovers are possible if the thermal variation of the interaction parameters is sufficiently strong. For materials with a smaller variation of the magnetic interactions which, as a consequence, exhibit no amplitude crossover no information on the temperature dependence of the magnetic interactions can be obtained from an analysis of mS(T)

  6. The CLASS system and the scheduling problem

    International Nuclear Information System (INIS)

    The need to process large quantities of data on the machine equipment of nuclear power plants and the high level of occurrence of recurrent technological procedures applied in maintenance will create the preconditions for the introduction of automated processing of this data and the subsequent automated control of units of centralized maintenance in nuclear power plants. For the said purposes the Research Institute for Nuclear Power Plants at Jaslovske Bohunice has selected activities suitable for automated processing and has experimentally applied to these activities the CLASS decision-making system operating with the CPM method. It is stated that the automated system for the operative control of repairs of nuclear power plants requires detailed information on conditions from which ensue the inter-relations between repairs. The choice of the most suitable sequence of operations should be left to the program which uses elements of artificial intelligence. Some aspects are discussed of the mathematical model of such a decision-making system in CLASS-AI operative control. (Z.M.)

  7. Four classes of interactions for evolutionary games

    Science.gov (United States)

    Szabó, György; Bodó, Kinga S.; Allen, Benjamin; Nowak, Martin A.

    2015-08-01

    The symmetric four-strategy games are decomposed into a linear combination of 16 basis games represented by orthogonal matrices. Among these basis games four classes can be distinguished as it is already found for the three-strategy games. The games with self-dependent (cross-dependent) payoffs are characterized by matrices consisting of uniform rows (columns). Six of 16 basis games describe coordination-type interactions among the strategy pairs and three basis games span the parameter space of the cyclic components that are analogous to the rock-paper-scissors games. In the absence of cyclic components the game is a potential game and the potential matrix is evaluated. The main features of the four classes of games are discussed separately and we illustrate some characteristic strategy distributions on a square lattice in the low noise limit if logit rule controls the strategy evolution. Analysis of the general properties indicates similar types of interactions at larger number of strategies for the symmetric matrix games.

  8. Initiating Interaction in the EFL Class

    Institute of Scientific and Technical Information of China (English)

    徐海仙

    2012-01-01

    In recent years,with the renewal of English textbooks of all levels,the traditional grammar-translation method is out-of-date in the EFL class.In order to meet the challenges of our age,more and more teachers have cast their eyes on the communicative use of language,which compels them to create opportunities for genuine interaction in the classroom.Interaction,according to Brown(1980,p.159),is "the collaborative exchange of thoughts,feelings,or ideas between two or more people resulting in a reciprocal effect on each other." As the core of communication,interaction is a very important word for current language teachers,who are responsible for providing the stimuli for continued interaction in the era of communicative language teaching.The significance of interaction in EFL class mainly lies in its contribution to the active teaching of grammar,the initiating of students’ intrinsic motivation and the improving of their communicative competence(c.c.).In this article,I will elaborate on why and how I initiate interaction by providing a 100-minute lesson plan in an attempt to connect theory with practice.

  9. One class of single negative acoustic metamaterials

    Science.gov (United States)

    Grekova, E. F.

    2015-05-01

    We consider linear elastic complex media the point-body motion of which is described by two vectorial generalized coordinates and the elastic energy contains a term coupling them. All constraints are holonomic and ideal. The dynamics of this continuum is determined by modified Lagrange equations. We specify a class of media whose strain energy depends only on one of the vectorial generalized coordinates, but does not depend on its gradient. We call this generalized coordinate "special." On the partial frequency of the special generalized coordinates under some conditions for the inertial and elastic characteristics, the medium behaves as a system of independent harmonic oscillators, and under other conditions, only the trivial solution exists. It is shown that independently of the nature of generalized coordinates, if the inertial and elastic tensors satisfy certain requirements, there exists a band gap of frequencies for most of the dispersion curves; i.e., the medium is a single negative acoustic metamaterial in this band of frequencies. The partial frequency of the "special" coordinate limits the band gap. For a specific class of parameters, apart from this, there exists a decreasing part of the dispersion curve; i.e., the medium is also a double negative acoustic metamaterial in a certain domain of frequencies.

  10. Skipping Economics Classes: A Case Study from Hong Kong

    Science.gov (United States)

    Chong, Terence Tai-Leung; Cheung, Ka-Shing; Hui, Pik-Hung

    2009-01-01

    This paper investigates the determinants of student attendance of economics classes. Course-specific and individual-specific factors are shown to have significant impacts on class attendance. It was found that female students and overseas students skip classes less often. Surprisingly, students involved in extra-curricular activities attend…

  11. 34 CFR 106.34 - Access to classes and schools.

    Science.gov (United States)

    2010-07-01

    ... coeducational elementary or secondary school may provide nonvocational single-sex classes or extracurricular activities, if— (i) Each single-sex class or extracurricular activity is based on the recipient's important... of the excluded sex, a substantially equal coeducational class or extracurricular activity in...

  12. 7 CFR 201.69 - Classes of certified seed.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Classes of certified seed. 201.69 Section 201.69..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.69 Classes of certified seed. (a) Classes of certified seed are as...

  13. Capitalizing on Stress Management Techniques in Developmental Classes.

    Science.gov (United States)

    Price, Elsa C.

    Mastering stress management techniques can help college developmental class educators protect themselves from burnout. These techniques can also be taught to students in developmental classes to enable them to maximize the benefits from these classes. This paper outlines the causes of stress, identifies stressors, describes responses to stress,…

  14. The Cultures of Social Class and Religious Educational Practice

    Science.gov (United States)

    Turpin, Katherine

    2009-01-01

    Although social class impacts the assumptions, values, and normative practices of Religious Education, the lack of public discourse on class diminishes awareness of and critical reflection on this impact. This article describes social class as a largely unarticulated and embodied performance of identity inflected through hierarchical practices of…

  15. Integrating Social Class into Vocational Psychology: Theory and Practice Implications

    Science.gov (United States)

    Diemer, Matthew A.; Ali, Saba Rasheed

    2009-01-01

    Although social class plays a salient and significant role in career development and occupational attainment, social class is underrepresented in vocational psychology theory, scholarship, and practice. Vocational psychologists are in a unique position to meet the career development needs of persons from all social classes by integrating a fuller…

  16. Class Formation, Politics, and Institutions: Schooling in the United States.

    Science.gov (United States)

    Rubinson, Richard

    1986-01-01

    Analyzes extent to which Marxist theories of social class influence can explain structure of schooling in the United States. Argues that theoretical and empirical flaws exist in Marxist studies and concludes that effects of class processes have been minimal compared to Europe because of a political system that has limited social class influences…

  17. 40 CFR 205.155 - Motorcycle class and manufacturer abbreviation.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Motorcycle class and manufacturer...) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Motorcycles § 205.155 Motorcycle class and manufacturer abbreviation. (a) Motorcycles must be grouped into classes determined...

  18. 32 CFR 1630.46 - Class 4-T: Treaty alien.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Class 4-T: Treaty alien. 1630.46 Section 1630.46 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION RULES § 1630.46 Class 4-T: Treaty alien. In Class 4-T shall be placed any registrant who is an alien...

  19. Morita equivalence and characteristic classes of star products

    CERN Document Server

    Bursztyn, H; Waldmann, S

    2009-01-01

    This paper deals with two aspects of the theory of characteristic classes of star products: first, on an arbitrary Poisson manifold, we describe Morita equivalent star products in terms of their Kontsevich classes; second, on symplectic manifolds, we describe the relationship between Kontsevich's and Fedosov's characteristic classes of star products.

  20. Communicative Teaching Method Applied in Oral English Class

    Institute of Scientific and Technical Information of China (English)

    黄峻峰; 黄芳

    2005-01-01

    This paper, based on some teaching experience and pedagogical theories, puts forward some tentative suggestions on how to improve the quality of oral English class. In addition, it mainly deals with some pragmatic aspects of oral class, which are believed to influence to a large extent the efficiency of oral English class.