WorldWideScience

Sample records for circulatory support system

  1. Biological evaluation of mechanical circulatory support systems in calves

    NARCIS (Netherlands)

    Rakhorst, G; VanDerMeer, J; Kik, C; Mihaylov, D; Havlik, P; Trinkl, J; Monties, [No Value

    1996-01-01

    Data from animal experiments with mechanical circulatory support systems (MCSS) performed in Groningen and Marseille over the past years were used to obtain normal values of hematological, coagulation, rheological and blood chemistry parameters in calves. These parameters were divided between two gr

  2. Nuclear-fueled circulatory support systems

    International Nuclear Information System (INIS)

    The authors studied nuclear artificial organs for the past 10 years, and have finally reached the stage of vital experiments on calves for two types of system of the nuclear left ventricular assist pump. These two systems use nuclear heat source containing 120 g, 1600 Ci Pu-238 (in the form of plutonium oxide). The heat source for the first system is the tidal regenerator engine controlled by electronics, with no valve or seal, and information on controlling is obtained from the hall effect displacement sensor. The second left ventricular assist system uses heat generated by nuclear decay for producing high gas pressure which is converted into a high hydraulic pressure for pumping. The engine efficiency amounts to 7-16%, and the measurement value of the pump efficiency obtained is 85%. It has been elucidated how these two systems are synchronized with the left ventricle of vital body. By a transplanting experiment for a short period (175 hours) in the initial stage, the possibility of the present method was clarified, and a long-term performance of vital experiment in parallel with improvement of the systems are anticipated. However, there still remain many pending questions such as improvement of efficiency, improvement of reliability, improvement of performance, and diminution of the size. (Chiba, N.)

  3. Nuclear-fueled circulatory support systems. XII. Current status

    International Nuclear Information System (INIS)

    Our laboratories have been engaged in development and in vivo testing of nuclear-fueled circulatory support systems. These efforts have focused on 4 major areas: (1) evaluations of the biologic effects of chronic intracorporeal heat and radiation; (2) the development of efficient and reliable energy converters (engines); (3) evaluations of the biocompatibility of the various system components, and (4) investigations of the hemodynamic effectiveness of the system in vivo. Previous in vivo experiments have been reported. Three systems are currently under investigation; each has undergone a number of modifications to improve overall thermal-mechanical efficiencies or to decrease physiologic alterations resulting from system size, intracorporeal heat and interactions between the prostheses and experimental animals. The purpose of this paper is to characterize the current systems and describe recent in vivo experiments

  4. Mathematical circulatory system model

    Science.gov (United States)

    Lakin, William D. (Inventor); Stevens, Scott A. (Inventor)

    2010-01-01

    A system and method of modeling a circulatory system including a regulatory mechanism parameter. In one embodiment, a regulatory mechanism parameter in a lumped parameter model is represented as a logistic function. In another embodiment, the circulatory system model includes a compliant vessel, the model having a parameter representing a change in pressure due to contraction of smooth muscles of a wall of the vessel.

  5. Status of the Tidal Regenerator Engine for nuclear circulatory support systems

    International Nuclear Information System (INIS)

    Based on the annular version of the Tidal Regenerator Engine, a packaged energy system for nuclear powered circulatory support systems was developed. Net power output of approximately 3 watts is delivered using a 33-watt heat source for an engine module volume of 0.7 liter and a weight of 1.6 kg. A higher efficiency dual cycle version of the annular engine using a Dowtherm A topping cycle on the basic steam cycle is also under development. Projected system output using this advanced engine is 5 watts for the same sized heat source. Life testing of critical components has demonstrated substantial reliability improvement over earlier designs. Of particular significance is the continuing operation of a complete implantable engine system after 1200 hours. Component life testing is continuing with over five thousand hours accumulated on two pump actuators employing welded metal bellows

  6. Introduction to circulatory and respiratory system modeling

    OpenAIRE

    Ferrari, Gianfranco; Darowski, Marek; Golczewski, Tomasz; Gorczynska, Krystyna; Kozarski, Maciej

    2010-01-01

    This chapter is focused on circulatory and respiratory system modeling. It includes a brief history of circulatory and respiratory system modeling development and a short description of the state of art. In the chapter also basic classification of mechanical circulatory and respiratory assistance is presented. The last part of the chapter deals with innovative approaches to modeling of both circulatory and respiratory system which concern hybrid models and virtual organs. Hybrid modeling cons...

  7. Postcardiotomy Mechanical Circulatory Support in Two Infants with Williams’ Syndrome

    OpenAIRE

    Contrafouris, Constantinos A.; Chatzis, Andrew C.; Kanakis, Meletios A.; Prodromos A. Azariadis; Mitropoulos, Fotios A

    2014-01-01

    Supravalvar aortic stenosis (SVAS) in patients with Williams' syndrome is often accompanied by coronary, pulmonary, and even myocardial lesions and therefore associated with increased perioperative morbidity and mortality. Extracorporeal membrane oxygenation (ECMO) provides reliable short-term mechanical circulatory support to patients, especially young, in acute postoperative cardiac failure when conventional means are ineffective. The incorporation of centrifugal pumps in these systems has ...

  8. Measurement science in the circulatory system

    OpenAIRE

    Jones, Casey M; Baker-Groberg, Sandra M.; Cianchetti, Flor A.; Glynn, Jeremy J.; Healy, Laura D.; Lam, Wai Yan; Nelson, Jonathan W.; Parrish, Diana C.; Phillips, Kevin G.; Scott-Drechsel, Devon E.; Tagge, Ian J.; Zelaya, Jaime E.; Hinds, Monica T.; McCarty, Owen J.T.

    2014-01-01

    The dynamics of the cellular and molecular constituents of the circulatory system are regulated by the biophysical properties of the heart, vasculature and blood cells and proteins. In this review, we discuss measurement techniques that have been developed to characterize the physical and mechanical parameters of the circulatory system across length scales ranging from the tissue scale (centimeter) to the molecular scale (nanometer) and time scales of years to milliseconds. We compare the uti...

  9. Postcardiotomy Mechanical Circulatory Support in Two Infants with Williams' Syndrome

    Science.gov (United States)

    Contrafouris, Constantinos A.; Chatzis, Andrew C.; Kanakis, Meletios A.; Azariadis, Prodromos A.; Mitropoulos, Fotios A.

    2014-01-01

    Supravalvar aortic stenosis (SVAS) in patients with Williams' syndrome is often accompanied by coronary, pulmonary, and even myocardial lesions and therefore associated with increased perioperative morbidity and mortality. Extracorporeal membrane oxygenation (ECMO) provides reliable short-term mechanical circulatory support to patients, especially young, in acute postoperative cardiac failure when conventional means are ineffective. The incorporation of centrifugal pumps in these systems has made their use more efficient and less traumatic. We describe our experience of using the Levitronix CentriMag pump in two patients with Williams' syndrome who underwent surgical correction of supravalvular aortic stenosis. PMID:24741444

  10. Pulsatile-flow mechanical circulatory support (MCS) as a bridge to transplantation or recovery. Single-centre experience with the POLCAS system in 2014

    Science.gov (United States)

    Kuśmierczyk, Mariusz; Szymański, Jarosław; Juraszek, Andrzej; Kołsut, Piotr; Kuśmierski, Krzysztof; Zieliński, Tomasz; Sobieszczańska-Małek, Małgorzata; Sitkowska-Rysiak, Ewa

    2015-01-01

    Introduction Mechanical circulatory support (MCS) is a recognised method of treatment for patients with end-stage chronic or acute heart failure. The POLCAS pulsatile-flow system has been used in our institution for 15 years. Currently, it is being widely replaced by continuous-flow mechanical circulatory support equipment of the second and third generations (HeartMateII, HeartWare). The MCS presented in this study is associated with a significant risk of complications and its use is increasingly considered controversial. The aim of the study was an evaluation of the results of treatment utilising the POLCAS MCS system at our institution in 2014. Material and methods The POLCAS system was implanted in 12 patients aged 16-63 years (42 ± 17 years) during a period of 12 months (from January to December, 2014). Full-blown cardiogenic shock was observed in all patients before MCS implantation. Four of the analysed patients (33%) required prior circulatory support with other devices: IABP (n = 2) or ECMO (n = 2). Episodes of cardiac arrest were reported in three patients; three other patients experienced serious arrhythmias, which accelerated the decision to implant MCS. The presented data was retrospectively obtained from the CliniNET system of the Institute of Cardiology. OpenOffice Calc spreadsheet was used for data analysis. Results Average MCS time was 41 days ± 25 (from 15 to 91 days). Survival until transplantation or explantation was 91.67%. The most frequent complications following the therapy were: cardiac tamponade or bleeding requiring an intervention – 25% (n = 3), renal failure requiring dialysis – 25% (n = 3), ischaemic stroke associated with the MCS – 16.6% (n = 2), bacteraemia – 16.6% (n = 2), and wound infection – 8% (n = 1). No malfunctions of the MCS system were reported. Early survival in patients who completed the MCS therapy, defined as discharge, amounted to 63.6% (n = 7). Conclusions The POLCAS heart assist system is an effective

  11. Representations of the Human Circulatory System

    Science.gov (United States)

    Lopez-Manjon, Asuncion; Angon, Yolanda Postigo

    2009-01-01

    There is no agreement about the robustness of intuitive representations of the circulatory system and their susceptibility to change by instruction. In this paper, we analyse to what extent students with varying degrees of biology instruction and different ages (High School Health Science and Social Science students and first and final year…

  12. Multi-scale simulation of circulatory system

    International Nuclear Information System (INIS)

    Multi-scale/multi-physical functions of human whole body circulatory systems can be simulated for their overall quantitative evaluation by integrated models of blood vessel geometry, substrate, mechanics, transport and physiology, and of which field is currently called physiome. The author has been developing such a simulation ultimately aiming at personalized medicare, and this paper describes its procedure and applications in vascular re-construction by medical images, in model constructions of the circulatory 0-dimensional hemodynamics and of autonomic nervous systems, in blood flow dynamics and function in the left ventricle, and in hemodynamic analysis of aorta. Physics of blood flow, the vascular modeling based on images like those of MRI and CT, and the bio-dynamic model for multi-scale calculation including actual examinations of simulated blood flow dynamics are described for the procedure and application. The simulation described will contribute to the medicare concerning clinical diagnosis, surgery prediction and new drug development. (S.I)

  13. The European Registry for Patients with Mechanical Circulatory Support (EUROMACS)

    DEFF Research Database (Denmark)

    de By, Theo M M H; Mohacsi, Paul; Gummert, Jan; Bushnaq, Hasan; Krabatsch, Thomas; Gustafsson, Finn; Leprince, Pascal; Martinelli, Luigi; Meyns, Bart; Morshuis, Michiel; Netuka, Ivan; Potapov, Evgenij; Zittermann, Armin; Delmo Walter, Eva Maria; Hetzer, Roland

    2015-01-01

    other founding international members. It aims to promote scientific research to improve care of end-stage heart failure patients with ventricular assist device or a total artificial heart as long-term mechanical circulatory support. Likewise, the organization aims to provide and maintain a registry of...

  14. Physics of the Circulatory System.

    Science.gov (United States)

    Van Heuvelen, Alan

    1989-01-01

    Discusses some calculations and demonstrations illustrating the role of physics in cardiovascular system. Describes a model for the system, work done by the heart, pressure in blood vessel, and gravitational effects. (YP)

  15. Automated diagnostic system of pathological states of the circulatory system

    OpenAIRE

    Книшов, Генадій Васильович; Настенко, Євген Арнольдович; Носовець, Олена Костянтинівна; Береговий, Олександр Анатолієвич; Шаповалова, Валентина Вікторівна; Плахтій, Артур Миколайович

    2014-01-01

    The results of developing an automated system of diagnosing pathological conditions of a human blood circulatory system have been presented. The system is based on the results of researching functional bonds between arterial blood pressure measurements and cardiac rate frequency in health and disease. Nomographic charts and percentage diagrams, reflecting the type of relation depending on a blood circulatory condition, have been used. The system development has been carried out by means of th...

  16. Instability conditions for circulatory and gyroscopic conservative systems

    CERN Document Server

    Birtea, Petre; Comanescu, Dan

    2011-01-01

    We give a method which generates sufficient conditions for instability of equilibria for circulatory and gyroscopic conservative systems. The method is based on the Gramians of a set of vectors whose coordinates are powers of the roots of the characteristic polynomial for the studied systems. New instability results are obtained for general circulatory and gyroscopic conservative systems. We also apply this method for studying the instability of motion for a charged particle in a stationary electromagnetic field.

  17. Pulmonary Hypertension in the Era of Mechanical Circulatory Support.

    Science.gov (United States)

    Krishnamurthy, Yamini; Cooper, Lauren B; Parikh, Kishan S; Felker, G Michael; Milano, Carmelo A; Rogers, Joseph G; Hernandez, Adrian F; Patel, Chetan B

    2016-01-01

    Left heart disease (LHD) represents the most common cause of pulmonary hypertension (PH), and is associated with worse prognosis compared with LHD without PH. In addition, PH due to LHD may prevent patients from receiving heart transplantation, because of risk of perioperative right ventricular failure. Current literature lacks comprehensive descriptions and management strategies of PH due to LHD. In this review, we summarize the literature that is available to highlight the definition, pathogenesis, and prognosis of PH due to LHD. Furthermore, we discuss the use of mechanical circulatory support (MCS) in this population. Finally, we provide recommendations regarding the management and reassessment of PH due to LHD in the specific context of MCS. PMID:27442856

  18. Staged Approach to Mechanical Circulatory Support and Recovered Allograft Function after Transplantation Rejection with Cardiogenic Shock

    OpenAIRE

    Caceres, Manuel; Czer, Lawrence S. C.; Esmailian, Fardad; Luthringer, Daniel; Ramzy, Danny; Moriguchi, Jaime

    2013-01-01

    Cardiogenic shock resulting from acute rejection after heart transplantation is an infrequent but life-threatening condition. Intensified immunosuppressive therapy and the timely initiation of properly selected mechanical circulatory support can be life-saving and enable recovery of graft function. The few published reports on mechanical circulatory support for acute transplantation rejection have focused on short-term devices.

  19. Contemporary mechanical circulatory support therapy for postcardiotomy shock.

    Science.gov (United States)

    Fukuhara, Shinichi; Takeda, Koji; Garan, Arthur Reshad; Kurlansky, Paul; Hastie, Jonathan; Naka, Yoshifumi; Takayama, Hiroo

    2016-04-01

    Significant progress has been made in the use of mechanical circulatory support (MCS), particularly in the clinical success in durable left ventricular assist device. Short-term MCS has also advanced in the form of venoarterial extracorporeal membrane oxygenation, external centrifugal VADs as well as percutaneous VADs. Postcardiotomy shock (PCS) is a rare clinical entity associated with substantial morbidity and mortality. It is characterized by heart failure that either results in an inability to wean from cardiopulmonary bypass or that occurs in the immediate postoperative period, accounting for the most common indication for MCS. The reported in-hospital mortality of the PCS patients remains high, consistently over 50 %, despite ongoing refinements of MCS technology. The optimization of selection criteria and the prompt institution of MCS are likely the keys to improving this persistently high mortality rate. Unfortunately, the lack of a clear definition for PCS in the literature limits scientific analyses and comparison of the existing evidence. To establish the treatment strategy and appropriately manage this challenging disease, substantial and fundamental effort by the cardiovascular society is imperative. PMID:26874519

  20. An Integrated Simulation Tool for Modeling the Human Circulatory System

    Science.gov (United States)

    Asami, Ken'ichi; Kitamura, Tadashi

    This paper presents an integrated simulation of the circulatory system in physiological movement. The large circulatory system model includes principal organs and functional units in modules in which comprehensive physiological changes such as nerve reflexes, temperature regulation, acid/base balance, O2/CO2 balance, and exercise are simulated. A beat-by-beat heart model, in which the corresponding electrical circuit problems are solved by a numerical analytic method, enables calculation of pulsatile blood flow to the major organs. The integration of different perspectives on physiological changes makes this simulation model applicable for the microscopic evaluation of blood flow under various conditions in the human body.

  1. 78 FR 49272 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2013-08-13

    ... HUMAN SERVICES Food and Drug Administration Circulatory System Devices Panel of the Medical Devices... long-term pulmonary support systems, one of the remaining preamendments class III devices regulated... depth of compressions for the duration of CPR. On January 8, 2013 (78 FR 1162), FDA issued a...

  2. Towards a Fast Dynamic Model of the Human Circulatory System

    Science.gov (United States)

    Kaplan, Carolyn; Green, Melissa; Boris, Jay; Oran, Elaine

    2011-11-01

    We describe a model for systems-level transport in the human circulatory system that is based on a set of equations for a one-dimensional unsteady elastic pipe flow circuit. The system is collapsed from three spatial dimensions and time to one spatial dimension and time by assuming axisymmetric vessel geometry and a parabolic velocity profile across the cylindrical vessels. To drive the fluid, the contractions of a beating heart are modeled as periodic area changes of the elastic vessels. Two different models are compared, both including and neglecting fluid acceleration. Time-resolved distributions of pressure, velocity and area compare reasonably well with reference data. Increasing the rigidity of the vasculature is found to increase peak arterial pressures on the order of ten percent, and including a distributed vascular contraction to model distributed skeletal muscle contractions monotonically increases time-averaged blood flow in the veins, consistent with human physiological response. The circulatory system model presented here simulates the circulatory system on the order of one hundred times faster than real-time; that is, we can compute thousands of heartbeats per minute of CPU time.

  3. Singular divergence instability thresholds of kinematically constrained circulatory systems

    International Nuclear Information System (INIS)

    Static instability or divergence threshold of both potential and circulatory systems with kinematic constraints depends singularly on the constraints' coefficients. Particularly, the critical buckling load of the kinematically constrained Ziegler's pendulum as a function of two coefficients of the constraint is given by the Plücker conoid of degree n=2. This simple mechanical model exhibits a structural instability similar to that responsible for the Velikhov–Chandrasekhar paradox in the theory of magnetorotational instability.

  4. Modeling the heart and the circulatory system

    CERN Document Server

    2015-01-01

    The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the flow in the systemic arterial tree and the complex electro-fluid-mechanical coupling in the human heart. Many examples of patient-specific simulations are presented. This book is addressed to all scientists interested in the mathematical modeling and numerical simulation of the human cardiocirculatory system.

  5. Functional stability of cerebral circulatory system

    Science.gov (United States)

    Moskalenko, Y. Y.

    1980-01-01

    The functional stability of the cerebral circulation system seems to be based on the active mechanisms and on those stemming from specific of the biophysical structure of the system under study. This latter parameter has some relevant criteria for its quantitative estimation. The data obtained suggest that the essential part of the mechanism for active responses of cerebral vessels which maintains the functional stability of this portion of the vascular system, consists of a neurogenic component involving central nervous structures localized, for instance, in the medulla oblongata.

  6. von Hippel-Lindau protein regulates transition from fetal to adult circulatory system in retina

    OpenAIRE

    Kurihara, Toshihide; Kubota, Yoshiaki; Ozawa, Yoko; Takubo, Keiyo; Noda, Kousuke; Simon, M. Celeste; Johnson, Randall S; Suematsu, Makoto; Tsubota, Kazuo; Ishida, Susumu; Goda, Nobuhito; Suda, Toshio; Okano, Hideyuki

    2010-01-01

    In the early neonatal stage, the fetal circulatory system undergoes dramatic transition to the adult circulatory system. Normally, embryonic connecting vessels such as ductus arteriosus and the foramen ovale close and regress. In the neonatal retina, hyaloid vessels maintaining blood flow in the embryonic retina regress, and retinal vessels take over to form adult-type circulatory system. This process is regulated by the programmed cell death switch mediated by macrophages via Wnt and Angiopo...

  7. Computational Hemodynamic Simulation of Human Circulatory System under Altered Gravity

    Science.gov (United States)

    Kim. Chang Sung; Kiris, Cetin; Kwak, Dochan

    2003-01-01

    A computational hemodynamics approach is presented to simulate the blood flow through the human circulatory system under altered gravity conditions. Numerical techniques relevant to hemodynamics issues are introduced to non-Newtonian modeling for flow characteristics governed by red blood cells, distensible wall motion due to the heart pulse, and capillary bed modeling for outflow boundary conditions. Gravitational body force terms are added to the Navier-Stokes equations to study the effects of gravity on internal flows. Six-type gravity benchmark problems are originally presented to provide the fundamental understanding of gravitational effects on the human circulatory system. For code validation, computed results are compared with steady and unsteady experimental data for non-Newtonian flows in a carotid bifurcation model and a curved circular tube, respectively. This computational approach is then applied to the blood circulation in the human brain as a target problem. A three-dimensional, idealized Circle of Willis configuration is developed with minor arteries truncated based on anatomical data. Demonstrated is not only the mechanism of the collateral circulation but also the effects of gravity on the distensible wall motion and resultant flow patterns.

  8. A Review of the “Open” and “Closed” Circulatory Systems: New Terminology for Complex Invertebrate Circulatory Systems in Light of Current Findings

    OpenAIRE

    Reiber, Carl L.; Iain J. McGaw

    2009-01-01

    Invertebrate cardiovascular systems have historically been viewed as sluggish, poorly regulated, and “open”, where blood bathes the tissues directly as it moves through a system of ill-defined sinuses and/or lacunae without an endothelial boundary. When examining cardiovascular/circulatory morphology and physiology in a broader evolutionary context, one can question the very nature of the definition of a “closed” versus “open” circulatory system. Viewed in ...

  9. The Circulatory System. Instructional Materials in Anatomy and Physiology for Pennsylvania Health Occupations Programs.

    Science.gov (United States)

    National Evaluation Systems, Inc., Amherst, MA.

    This instructional modular unit with instructor's guide provides materials on aspects of one of the major systems of the human body--the circulatory system. Its purpose is to introduce the student to the structures and functions of the human circulatory system--and the interrelationships of the two--and to familiarize the student with some of the…

  10. ICD-11 and SNOMED CT Common Ontology: circulatory system.

    Science.gov (United States)

    Rodrigues, Jean-Marie; Schulz, Stefan; Rector, Alan; Spackman, Kent; Millar, Jane; Campbell, James; Ustün, Bedirhan; Chute, Christopher G; Solbrig, Harold; Della Mea, Vincenzo; Persson, Kristina Brand

    2014-01-01

    The improvement of semantic interoperability between data in electronic health records and aggregated data for health statistics requires efforts to carefully align the two domain terminologies ICD and SNOMED CT. Both represent a new generation of ontology-based terminologies and classifications. The proposed alignment of these two systems and, in consequence, the validity of their cross-utilisation, requires a specific resource, named Common Ontology. We present the ICD-11 SNOMED CT Common Ontology building process including: a) the principles proposed for aligning the two systems with the help of a common model of meaning, b) the design of this common ontology, and c) preliminary results of the application to the diseases of the circulatory system. PMID:25160347

  11. Use of Short-term Circulatory Support as a Bridge in Pediatric Heart Transplantation

    Directory of Open Access Journals (Sweden)

    Luiz Fernando Canêo

    2015-01-01

    Full Text Available Background: Heart transplantation is considered the gold standard therapy for the advanced heart failure, but donor shortage, especially in pediatric patients, is the main limitation for this procedure, so most sick patients die while waiting for the procedure. Objective: To evaluate the use of short-term circulatory support as a bridge to transplantation in end-stage cardiomyopathy. Methods: Retrospective clinical study. Between January 2011 and December 2013, 40 patients with cardiomyopathy were admitted in our Pediatric Intensive Care Unit, with a mean age of 4.5 years. Twenty patients evolved during hospitalization with clinical deterioration and were classified as Intermacs 1 and 2. One patient died within 24 hours and 19 could be stabilized and were listed. They were divided into 2 groups: A, clinical support alone and B, implantation of short-term circulatory support as bridge to transplantation additionally to clinical therapy. Results: We used short-term mechanical circulatory support as a bridge to transplantation in 9. In group A (n=10, eight died waiting and 2 patients (20% were transplanted, but none was discharged. In group B (n=9, 6 patients (66.7% were transplanted and three were discharged.The mean support time was 21,8 days (6 to 984h. The mean transplant waiting list time was 33,8 days. Renal failure and sepsis were the main complication and causeof death in group A while neurologic complications were more prevalent en group B. Conclusion: Mechanical circulatory support increases survival on the pediatric heart transplantation waiting list in patients classified as Intermacs 1 and 2.

  12. 77 FR 18829 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2012-03-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Circulatory System Devices Panel of the Medical Devices... (FDA). The meeting will be open to the public. Name of Committee: Circulatory System Devices Panel...

  13. FEATURES OF LONG-TERM MECHANICAL CIRCULATORY SUPPORT WITH CONTINUOUS-FLOW PUMP

    Directory of Open Access Journals (Sweden)

    G. P. Itkin

    2012-01-01

    Full Text Available In a review of the comparative analysis of methods and tools for long-term mechanical circulatory support with continuous flow and pulsatile flow implantable pumps. Particular attention is paid to the choice of the optimal modes of the operation of pumps based on the physical principles of the interaction between a the steady flow of blood to the pulsatile mechanics of the heart chambers. 

  14. Hemocompatibility of Axial Versus Centrifugal Pump Technology in Mechanical Circulatory Support Devices.

    Science.gov (United States)

    Schibilsky, David; Lenglinger, Matthias; Avci-Adali, Meltem; Haller, Christoph; Walker, Tobias; Wendel, Hans Peter; Schlensak, Christian

    2015-08-01

    The hemocompatible properties of rotary blood pumps commonly used in mechanical circulatory support (MCS) are widely unknown regarding specific biocompatibility profiles of different pump technologies. Therefore, we analyzed the hemocompatibility indicating markers of an axial flow and a magnetically levitated centrifugal device within an in vitro mock loop. The HeartMate II (HM II; n = 3) device and a CentriMag (CM; n = 3) adult pump were investigated in a human whole blood mock loop for 360 min using the MCS devices as a driving component. Blood samples were analyzed by enzyme-linked immunosorbent assay for markers of coagulation, complement system, and inflammatory response. There was a time-dependent activation of the coagulation (thrombin-antithrombin complexes [TAT]), complement (SC5b-9), and inflammation system (polymorphonuclear [PMN] elastase) in both groups. The mean value of TAT (CM: 4.0 μg/L vs. 29.4 μg/L, P centrifugal CM device showed significantly lower activation of coagulation and inflammation than that of the HM II axial flow pump. Both HM II and CM have demonstrated an acceptable hemocompatibility profile in patients. However, there is a great opportunity to gain a clinical benefit by developing techniques to lower the blood surface interaction within both pump technologies and a magnetically levitated centrifugal pump design might be superior. PMID:26234452

  15. Numerical models: realization and applications. Circulatory system models

    OpenAIRE

    Ferrari, Gianfranco; Lazzari, Claudio,; Zielinski, Krzysztof; Fresiello, Libera; Palko, Krzysztof Jakub

    2010-01-01

    This chapter illustrates the basic structure, the organization and some examples of digital computer circulatory models applications. A special attention is given to the realization of graphical user interfaces and to choice of software platforms. Mechanical circulatory assistance is treated giving two examples where it is represented with two different approaches: representing the physical device or its functional aspects. The parallel LVAD assistance is simulated modeling the pneumatic vent...

  16. Evaluation of exercise-respiratory system modifications and preliminary respiratory-circulatory system integration scheme

    Science.gov (United States)

    Gallagher, R. R.

    1974-01-01

    The respiratory control system, functioning as an independent system, is presented with modifications of the exercise subroutine. These modifications illustrate an improved control of ventilation rates and arterial and compartmental gas tensions. A very elementary approach to describing the interactions of the respiratory and circulatory system is presented.

  17. 77 FR 25183 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2012-04-27

    ... HUMAN SERVICES Food and Drug Administration Circulatory System Devices Panel of the Medical Devices... the Medical Devices Advisory Committee. General Function of the Committee: To provide advice and... Commissioner for Special Medical Programs. BILLING CODE 4160-01-P...

  18. Energy transmission and power sources for mechanical circulatory support devices to achieve total implantability.

    Science.gov (United States)

    Wang, Jake X; Smith, Joshua R; Bonde, Pramod

    2014-04-01

    Left ventricular assist device therapy has radically improved congestive heart failure survival with smaller rotary pumps. The driveline used to power today's left ventricular assist devices, however, continues to be a source of infection, traumatic damage, and rehospitalization. Previous attempts to wirelessly power left ventricular assist devices using transcutaneous energy transfer systems have been limited by restrictions on separation distance and alignment between the transmit and receive coils. Resonant electrical energy transfer allows power delivery at larger distances without compromising safety and efficiency. This review covers the efforts to wirelessly power mechanical circulatory assist devices and the progress made in enhancing their energy sources. PMID:24530103

  19. The Circulatory System [and] Instructor's Guide: The Circulatory System. Health Occupations Education Module: Instructional Materials in Anatomy and Physiology for Pennsylvania Health Occupations Programs.

    Science.gov (United States)

    National Evaluation Systems, Inc., Amherst, MA.

    This module on the circulatory system is one of 17 modules designed for individualized instruction in health occupations education programs at both the secondary and postsecondary levels. It is part of an eight-unit subset on anatomy and physiology within the set of 17 modules. Following a preface which explains to the student how to use the…

  20. Challenges in long-term mechanical circulatory support and biological replacement of the failing heart.

    Science.gov (United States)

    Lala, Anuradha; Joyce, Emer; Groarke, John D; Mehra, Mandeep R

    2014-01-01

    The burden of advanced heart failure is reaching epidemic proportions. Generally considered for cardiac transplantation, patients often cannot receive this therapy because of their advanced age, comorbidity or the scarcity of donors. Most transplants are concentrated in North America and Europe, with the average center performing fewer than 20 annual transplants. A search for nonbiological means of cardiac support has led to the advent of mechanical circulatory support (MCS), a concept now entrenched as a bridge to transplantation or, for those ineligible for transplantation, as lifetime therapy. In this review we discuss contemporary challenges posed by the changing epidemiology of cardiac transplant and MCS and outline the basis for an understanding of the future of this important therapeutic stance.   PMID:24451651

  1. Developing Seventh Grade Students’ Systems Thinking Skills in the Context of the Human Circulatory System

    OpenAIRE

    Raved, Lena; Yarden, Anat

    2014-01-01

    Developing systems thinking skills in school can provide useful tools to deal with a vast amount of medical and health information that may help learners in decision making in their future lives as citizen. Thus, there is a need to develop effective tools that will allow learners to analyze biological systems and organize their knowledge. Here, we examine junior high school students’ systems thinking skills in the context of the human circulatory system. A model was formulated for developing ...

  2. Durable mechanical circulatory support in advanced heart failure: a critical care cardiology perspective.

    Science.gov (United States)

    Lala, Anuradha; Mehra, Mandeep R

    2013-11-01

    Though cardiac transplantation for advanced heart disease patients remains definitive therapy for patients with advanced heart failure, it is challenged by inadequate donor supply, causing durable mechanical circulatory support (MCS) to slowly become a new primary standard. Selecting appropriate patients for MCS involves meeting a number of prespecifications as is required in evaluation for cardiac transplant candidacy. As technology evolves to bring forth more durable smaller devices, selection criteria for appropriate MCS recipients will likely expand to encompass a broader, less sick population. The "Holy Grail" for MCS will be a focus on clinical recovery and explantation of devices rather than the currently more narrowly defined indications of bridge to transplantation or lifetime device therapy. PMID:24188222

  3. Toward a Theory of the Primo Vascular System: A Hypothetical Circulatory System at the Subcellular Level

    OpenAIRE

    Byung-Cheon Lee; Ji Woong Yoon; Sang Hyun Park; Seung Zhoo Yoon

    2013-01-01

    This paper suggests a theoretical framework for the primo vascular system (PVS), a hypothetical circulatory system, in which extracellular DNA microvesicles interact to form and break down cell structures. Since Bonghan Kim reported the existence of Bonghan ducts and the SNU research team reinvestigated and named it the PVS, there has been series of studies trying to examine its structure and functions. In this paper, we hypothesize that the PVS is the network system in which extracellular DN...

  4. THE FIRST EXPERIENCE IN CLINICAL APPLICATION OF DOMESTIC CIRCULATORY SUPPORT DEVICE ON BASIS OF IMPLANTABLE AXIAL PUMP FOR TWO STAGE HEART TRANSPLANTATION

    Directory of Open Access Journals (Sweden)

    S. V. Gautier

    2013-01-01

    Full Text Available The paper describes the first clinical experience in RF of successful application of domestic circulatory support device based on implantable axial pump for two stage heart transplantation. This case demonstrate the effec- tiveness and safety of our device (АВК-Н for a longtime (270 days left ventricular bypass and the ability to perform a successful transplantation of donor,s heart after application of this system

  5. Mechanical Circulatory Support Devices Improve Tissue Perfusion in Patients With End-Stage Heart Failure or Cardiogenic Shock

    NARCIS (Netherlands)

    C.A. den Uil; A.P. Maat; W.K. Lagrand; M. van der Ent; L.S.D. Jewbali; R.J. van Thiel; P.E. Spronk; M.L. Simoons

    2009-01-01

    Objectives: This study evaluated the effects of mechanical circulatory support (MCS) on sub-lingual microcirculation as a surrogate for splanchnic microvascular perfusion. Methods: Between May 2008 and April 2009, 10 consecutive patients received an MCS device or extracorporeal membrane oxygenation

  6. Estimation system of cardiovascular circulatory system state based on 24h heart rate

    OpenAIRE

    Kyselova, Olga; Nastenko, Yevgen

    2013-01-01

    The goal of this research was to develop the methods and tools for the analysis of cardiovascular circulatory system states, early prediction of the probability of sudden cardiac arrest, as well as analysis of various cardiac arrhythmias based on the dynamics of the 24-hours heart rate. Using «k-means" method based on MacQueen algorithm, the automated classification of heart rate fragments was made. The most informative procedure was referring specific observation to the functional pattern...

  7. 76 FR 58019 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2011-09-19

    ... HUMAN SERVICES Food and Drug Administration Circulatory System Devices Panel of the Medical Devices... the Medical Devices Advisory Committee. General Function of the Committee: To provide advice and... Medtronic Ablation Frontiers Cardiac Ablation System is a catheter-based device developed for the...

  8. 76 FR 56200 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2011-09-12

    ... HUMAN SERVICES Food and Drug Administration Circulatory System Devices Panel of the Medical Devices... the Medical Devices Advisory Committee. General Function of the Committee: To provide advice and... and are pre-loaded onto 6 or 7 Fr \\1\\ (diameter of 2 or 2.3 mm) delivery systems. Upon deployment,...

  9. 76 FR 63928 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2011-10-14

    ... HUMAN SERVICES Food and Drug Administration Circulatory System Devices Panel of the Medical Devices... the Medical Devices Advisory Committee. General Function of the Committee: To provide advice and... stable, optimal medical therapy, and who have left bundle branch block (LBBB) with a QRS duration...

  10. 77 FR 66847 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2012-11-07

    ... HUMAN SERVICES Food and Drug Administration Circulatory System Devices Panel of the Medical Devices... the Medical Devices Advisory Committee. General Function of the Committee: To provide advice and... releasing external pressure during systole to reduce left ventricular workload. On March 9, 1979 (44...

  11. 78 FR 11208 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2013-02-15

    ... HUMAN SERVICES Food and Drug Administration Circulatory System Devices Panel of the Medical Devices... the Medical Devices Advisory Committee. General Function of the Committee: To provide advice and... three major components: The delivery catheter, the steerable sleeve, and the MitraClip device. The...

  12. 75 FR 7282 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2010-02-18

    ... HUMAN SERVICES Food and Drug Administration Circulatory System Devices Panel of the Medical Devices... the Medical Devices Advisory Committee. General Function of the Committee: To provide advice and... Warner, Acting Associate Commissioner for Special Medical Programs. BILLING CODE 4160-01-S...

  13. 78 FR 67365 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2013-11-12

    ... HUMAN SERVICES Food and Drug Administration Circulatory System Devices Panel of the Medical Devices... the Medical Devices Advisory Committee. General Function of the Committee: To provide advice and... percutaneously delivered permanent cardiac implant placed in the left atrial appendage. This device is...

  14. 76 FR 36548 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2011-06-22

    ... HUMAN SERVICES Food and Drug Administration Circulatory System Devices Panel of the Medical Devices... the Medical Devices Advisory Committee. General Function of the Committee: To provide advice and... vote on information related to the humanitarian device exemption for the Berlin Heart EXCOR...

  15. 75 FR 81282 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2010-12-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Circulatory System Devices Panel of the Medical Devices... the Medical Devices Advisory Committee. General Function of the Committee: To provide advice...

  16. The Persistence of Misconceptions about the Human Blood Circulatory System among Students in Different Grade Levels

    Science.gov (United States)

    Ozgur, Sami

    2013-01-01

    In this paper, it is aimed to investigate the persistence of misconceptions in the topic of the human blood circulatory system among students in different grade levels. For this reason, after discussions with biology educators, two tests consisting of open-ended questions were developed by the researcher and administered to students in four…

  17. Facilitating Conceptual Change in Ninth Grade Students' Understanding of Human Circulatory System Concepts

    Science.gov (United States)

    Alkhawaldeh, Salem A.

    2007-01-01

    The purpose of this study was to investigate the effectiveness of the conceptual change text oriented instruction over traditionally designed instruction on ninth grade students' understanding of the human circulatory system concepts, and their retention of this understanding. The subjects of this study consist of 73 ninth grade female students…

  18. Learning in a Non-Physical Science Domain: The Human Circulatory System.

    Science.gov (United States)

    Chi, Michelene T. H.; And Others

    This research explores the moment-by-moment understanding students exhibit in the learning of a non-physical science domain--the human circulatory system. The goal was to understand how students learn by capturing the nature of their initial mental models (naive conceptions), and by seeing how new information gets assimilated into their mental…

  19. Students' Achievement in Human Circulatory System Unit: The Effect of Reasoning Ability and Gender.

    Science.gov (United States)

    Sungur, Semra; Tekkaya, Ceren

    2003-01-01

    Investigates the effect of gender and reasoning ability on the human circulatory system concepts achievement and attitude toward biology. Reports a statistically significant mean difference between concrete and formal students with regard to achievement and attitude toward biology. (Contains 24 references.) (Author/YDS)

  20. Students' Alternative Conceptions of the Human Circulatory System: A Cross-Age Study.

    Science.gov (United States)

    Arnaudin, Mary W.; Mintzes, Joel J.

    1985-01-01

    Concept maps and structured/clinical interviews were completed by 25 fourth graders and 25 college freshmen to determine knowledge of the human circulatory system. Students (N=945) at various levels were then measured for misconception frequencies. Student preconceptions appear to be tenacious, but confrontation strategies may assist fundamental…

  1. PERIPHERAL VENO-ARTERIAL ECMO AS MECHANICAL CIRCULATORY SUPPORT BEFORE HEART TRANSPLANTATION

    Directory of Open Access Journals (Sweden)

    E. A. Spirina

    2013-01-01

    Full Text Available Aim of our clinical study was evaluation own initial experience of high-urgency ortotopic heart transplantation (OHT in recipients, who were bridged on peripheral Vena-Arterial Extracorporeal Membrane Oxygenation (VA ECMO. Materials and methods. In this study was included 17 patients (14/3 M/F, age 16–66 (40.1 ± 4.2 yrs who underwent OHT while on peripheral ECMO support. In all cases we used peripheral surgical can- nulation technique via femoral vessels – arterial cannula 15–19 Fr, venous cannula – 21–25 Fr, arterial cannula or vascular catheter 8–10 Fr for anterograde leg’s perfusion. Results. Duration Vena-Arterial Extracorporeal Membrane Oxygenation before OHT was 81 ± 17 h. VA ECMO support was blood flow 4.8 ± 0.6 l/min or 2.63 ± 0/04 l/min/m2, gas flow 4.8 ± 0.6 l/min, FiO2 0.86 ± 0.07. Vena-Arterial Extracorporeal Membrane Oxygenation support was continued in “protective mode” (blood flow 1.9 ± 0.2 l/min 4.3 ± 0.5 days after OHT. Thirteen pa- tients (76.4% were weaned from VA ECMO successfully and survived to be discharged. ICU and hospital LOS after orthotopic heart transplantation was respectively 6.7 ± 0.8 and 32.3 ± 4.6 days in group of survived patients. The reasons of a lethal outcome (n = 4, 23.5% were sepsis and multiorgan failure (n = 3, sudden cardiac arrest (n = 1. Conclusion. Vena-Arterial Extracorporeal Membrane Oxygenation is a favorable short-term method of circulatory support in patients who needed in high-urgency heart transplantation. 

  2. Optimization of Centrifugal Pump Characteristic Dimensions for Mechanical Circulatory Support Devices.

    Science.gov (United States)

    Korakianitis, Theodosios; Rezaienia, Mohammad A; Paul, Gordon M; Rahideh, Akbar; Rothman, Martin T; Mozafari, Sahand

    2016-01-01

    The application of artificial mechanical pumps as heart assist devices impose power and size limitations on the pumping mechanism, and therefore requires careful optimization of pump characteristics. Typically new pumps are designed by relying on the performance of other previously designed pumps of known performance using concepts of fluid dynamic similarity. Such data are readily available for industrial pumps, which operate in Reynolds numbers region of 10. Heart assist pumps operate in Reynolds numbers of 10. There are few data available for the design of centrifugal pumps in this characteristic range. This article develops specific speed versus specific diameter graphs suitable for the design and optimization of these smaller centrifugal pumps concentrating in dimensions suitable for ventricular assist devices (VADs) and mechanical circulatory support (MCS) devices. A combination of experimental and numerical techniques was used to measure and analyze the performance of 100 optimized pumps designed for this application. The data are presented in the traditional Cordier diagram of nondimensional specific speed versus specific diameter. Using these data, nine efficient designs were selected to be manufactured and tested in different operating conditions of flow, pressure, and rotational speed. The nondimensional results presented in this article enable preliminary design of centrifugal pumps for VADs and MCS devices. PMID:27258221

  3. Developing 7th grade students' systems thinking skills in the context of the human circulatory system

    Directory of Open Access Journals (Sweden)

    Lena eRaved

    2014-12-01

    Full Text Available Developing systems thinking skills in school can provide useful tools to deal with a vast amount of medical and health information that may help learners in decision making in their future lives as citizen. Thus, there is a need to develop effective tools that will allow learners to analyze biological systems and organize their knowledge. Here we examine junior high school students' systems thinking skills in the context of the human circulatory system. A model was formulated for developing teaching and learning materials and for characterizing students' systems thinking skills. Specifically we asked whether 7th grade students, who studied about the human circulatory system, acquired systems thinking skills and what are the characteristics of those skills? Concept maps were used to characterize students' systems thinking components and examine possible changes in the students' knowledge structure. These maps were composed by the students before and following the learning process. The study findings indicate a significant improvement in the students' ability to recognize the system components and the processes that occur within the system, as well as the relationships between different levels of organization of the system, following the learning process. Thus, following learning students were able to organize the systems’ components and its processes within a framework of relationships, namely the students' systems thinking skills were improved in the course of learning using the teaching and learning materials.

  4. Hemodynamic assessment of partial mechanical circulatory support: data derived from computed tomography angiographic images and computational fluid dynamics

    OpenAIRE

    Karmonik, Christof; Partovi, Sasan; Rengier, Fabian; Meredig, Hagen; Farag, Mina Berty; Müller-Eschner, Matthias; Arif, Rawa; Popov, Aron-Frederik; Kauczor, Hans-Ulrich; Karck, Matthias; Ruhparwar, Arjang

    2015-01-01

    Partial mechanical circulatory support represents a new concept for the treatment of advanced heart failure. The Circulite Synergy Micro Pump®, where the inflow cannula is connected to the left atrium and the outflow cannula to the right subclavian artery, was one of the first devices to introduce this concept to the clinic. Using computational fluid dynamics (CFD) simulations, hemodynamics in the aortic tree was visualized and quantified from computed tomography angiographic (CTA) images in ...

  5. Extracorporeal circulatory systems in the interhospital transfer of critically ill patients: experience of a single institution

    International Nuclear Information System (INIS)

    Critically ill patients with acute circulatory failure cannot be moved to other institutions unless stabilized by mechanical support systems. Extracorporeal heart and lung assist systems are increasingly used as a bridge to end-organ recovery or transplantation, and as an ultimate rescue tool in cardiopulmonary resuscitation. From July 2001 to April 2008, we had 38 requests for extracorporeal support for interhospital transfer carried out by the air medical service. Respiratory failure was present in 29 patients, who were provided with pumpless extracorporeal lung assist (PECLA) or veno-venous extracorporeal membrane oxygenation (ECMO). Cardiac failure dominated in 9 patients, who underwent implantation of extracorporeal life support (ECLS). Underlying diseases were acute respiratory distress syndrome in 15 patients, pneumonia in 7, prior lung transplant status in 4, cardiogenic shock in 7, and septic shock in 4. All assist systems were connected via peripheral vessels by the Seldinger technique. Transport was uneventful in all cases with no technical failures. On arrival at the specialized care hospital, two patients had leg ischemia and underwent relocation of the arterial cannula. After a mean (SD) support of 5.1 (3.0) days for PECLA, 3.5 (2.9) days for ECLS, and 7.3 (5.8) days for ECMO, 60%, 66%, and 66% of patients, respectively, could be successfully weaned from the systems. Discharge rates were 45% for PECLA, 44% for ECLS, and 56% for ECMO. Our experience proves that minimized extracorporeal assist devices allow safe assistance of patients with isolated or combined heart and lung failure in need of interhospital transfer. Critically ill patients get a chance to reach a center of maximum medical care. (author)

  6. A Coupled Biventricular Finite Element and Lumped Parameter Circulatory System Model of Heart Failure

    OpenAIRE

    Wenk, Jonathan F.; Ge, Liang; Zhang, Zhihong; Soleimani, Mehrdad; Potter, D Dean; Wallace, Arthur W.; Ratcliffe, Mark B.; Guccione, Julius M.

    2012-01-01

    Numerical modeling of the cardiovascular system is becoming an important tool for assessing the influence of heart disease and treatment therapies. In the current study we present an approach for modeling the interaction between the heart and circulatory system. This was accomplished by creating animal specific biventricular finite element models, which characterize the mechanical response of the heart, and coupling them to a lumped parameter model that represents the systemic and pulmonic ci...

  7. A coupled biventricular finite element and lumped-parameter circulatory system model of heart failure

    OpenAIRE

    Wenk, JF; Ge, L.; Zhang, Z.; Soleimani, M.; Potter, DD; Wallace, AW; Tseng, E; Ratcliffe, MB; Guccione, JM

    2012-01-01

    Numerical modelling of the cardiovascular system is becoming an important tool for assessing the influence of heart disease and treatment therapies. In the current study, we present an approach for modelling the interaction between the heart and the circulatory system. This was accomplished by creating animal-specific biventricular finite element (FE) models, which characterise the mechanical response of the heart, and by coupling them to a lumped-parameter model that represents the systemic ...

  8. Nursing diagnoses and outcomes related to the circulatory-system terms (ICNP® represented in an ontology

    Directory of Open Access Journals (Sweden)

    Marcia Regina Cubas

    2013-10-01

    Full Text Available The aim of the present study was to develop titles of Nursing Diagnoses and Outcomes (ND/NO through the relationship between the terms of the Focus axis, limited to the Circulatory System Process, and the terms of other ICNP® axes and to integrate these terms into an ontology. Titles were developed linking 17 terms of the focus axis, which were evaluated by expert nurses in five Brazilian cities. Titles whose use concordance was above 0.80 were included in the ontology. In total, 89 titles for ND/NO were supported in the literature, and 19 were not supported; 37 were assessed as eligible for use in healthcare practice and were included in the ontology. The construction of ND/NO titles based on the ICNP® and using a formal representation of knowledge is a task that requires deepening concepts used for nursing and adequate classification revisions. The elaborated titles will facilitate the composition of diagnostics that are more consistent with practice.

  9. Myocardial Oxidative Metabolism and Protein Synthesis during Mechanical Circulatory Support by Extracorporeal Membrane Oxygenation

    Energy Technology Data Exchange (ETDEWEB)

    Priddy, MD, Colleen M.; Kajimoto, Masaki; Ledee, Dolena; Bouchard, Bertrand; Isern, Nancy G.; Olson, Aaron; Des Rosiers, Christine; Portman, Michael A.

    2013-02-01

    Extracorporeal membrane oxygenation (ECMO) provides mechanical circulatory support essential for survival in infants and children with acute cardiac decompensation. However, ECMO also causes metabolic disturbances, which contribute to total body wasting and protein loss. Cardiac stunning can also occur which prevents ECMO weaning, and contributes to high mortality. The heart may specifically undergo metabolic impairments, which influence functional recovery. We tested the hypothesis that ECMO alters oxidative. We focused on the amino acid leucine, and integration with myocardial protein synthesis. We used a translational immature swine model in which we assessed in heart (i) the fractional contribution of leucine (FcLeucine) and pyruvate (FCpyruvate) to mitochondrial acetyl-CoA formation by nuclear magnetic resonance and (ii) global protein fractional synthesis (FSR) by gas chromatography-mass spectrometry. Immature mixed breed Yorkshire male piglets (n = 22) were divided into four groups based on loading status (8 hours of normal circulation or ECMO) and intracoronary infusion [13C6,15N]-L-leucine (3.7 mM) alone or with [2-13C]-pyruvate (7.4 mM). ECMO decreased pulse pressure and correspondingly lowered myocardial oxygen consumption (~ 40%, n = 5), indicating decreased overall mitochondrial oxidative metabolism. However, FcLeucine was maintained and myocardial protein FSR was marginally increased. Pyruvate addition decreased tissue leucine enrichment, FcLeucine, and Fc for endogenous substrates as well as protein FSR. Conclusion: The heart under ECMO shows reduced oxidative metabolism of substrates, including amino acids, while maintaining (i) metabolic flexibility indicated by ability to respond to pyruvate, and (ii) a normal or increased capacity for global protein synthesis, suggesting an improved protein balance.

  10. Cardiolab: A Virtual Laboratory for the analysis of Human Circulatory System

    OpenAIRE

    Hernandez, Alher Mauricio; Pierfranco Herrera, Gino; Mañanas Villanueva, Miguel Ángel; Costa Castelló, Ramon

    2009-01-01

    One of the career areas included in the field of Biomedical Engineering is the application of engineering system analysis: physiological modelling, simulation and control. This paper describes a Virtual Laboratory for the analysis and the study of Human circulatory system. The Virtual Laboratory is based on the compilation of several mathematical models described in the literature. Presented application has been build using MATLAB/ Simulink and EJS, so it combines good...

  11. Burden of Circulatory System Diseases and Ignored Barriers ofKnowledge Translation

    OpenAIRE

    Hamed-Basir Ghafouri; Shahzad Saravani; Farhad Shokraneh

    2012-01-01

    Circulatory system disease raise third highest disability-adjusted life years among Iranians and ischemic cardiac diseases are main causes for such burden. Despite available evidences on risk factors of the disease, no effective intervention was implemented to control and prevent the disease. This paper non-systematically reviews available literature on the problem, solutions, and barriers of implementation of knowledge translation in Iran. It seems that there are ignored factors such as cult...

  12. Burden of Circulatory System Diseases and Ignored Barriers of Knowledge Translation

    OpenAIRE

    Ghafouri, Hamed-Basir; Saravani, Shahzad; Shokraneh, Farhad

    2012-01-01

    Circulatory system disease raise third highest disability-adjusted life years among Iranians and ischemic cardiac diseases are main causes for such burden. Despite available evidences on risk factors of the disease, no effective intervention was implemented to control and prevent the disease. This paper non-systematically reviews available literature on the problem, solutions, and barriers of implementation of knowledge translation in Iran. It seems that there are ignored factors such as cult...

  13. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems

    CERN Document Server

    Thiriet, Marc

    2013-01-01

    The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to phenomenological models of nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 4 is devoted to major sets of intracellular mediators that transmit signals upon stimulation of cell-surface receptors.  Activation of...

  14. Control of Cell Fate in the Circulatory and Ventilatory Systems

    CERN Document Server

    Thiriet, Marc

    2012-01-01

    The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volumes 1 and 2 are devoted to cell organization and fate, as well as activities that are autoregulated and/or controlled by the cell environment. Volume 1 examined cellular features that allow adaptation to env...

  15. Mortality due to diseases of the circulatory system among the elderly population in Brazilian Amazon: temporal and spatial analysis

    OpenAIRE

    Karine Vila Real Nunes; Sandra Mara Alves da Silva Neves; Eliane Ignotti

    2013-01-01

    INTRODUCTION: Circulatory Diseases (CD) are the major cause of death among the elderly population in Brazilian Amazon. OBJECTIVE: to analyze standardized mortality rates of diseases of the circulatory system (DCS), according to the main causes of death among the elderly, in microregions of the Brazilian Amazon, in the period of 1998 - 2007. METHODS: ecological study of mortality rates distribution standardized by CD and corrected by deaths from poorly defined causes among the elderly (> 65 ye...

  16. Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems

    CERN Document Server

    Thiriet, Marc

    2013-01-01

    The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. Volume 5 is devoted to cells, tissues, and organs of the cardiovascular and ventilatory systems with an emphasis on mechanotransduction-based regulation of flow. The blood vessel wall is a living tissue that quickly reacts to loads applied on it by the flowing blood. In any segment of a blood vessel, the endothelial and smooth muscle cells can sense unusual time variations in small-magnitude wall shear stress and large-amplitude wall stretch generated by abnormal hemodynamic stresses. These cells respond with a short-time scale (from seconds to hours) to adapt the vessel caliber. Since such adaptive cell activities can be described using mathematical models, a key objective of this volume is to identify the mesoscopic agents and nanoscopic mediators required to derive adequate mathematical models...

  17. Von Willebrand factor in patients on mechanical circulatory support – a double-edged sword between bleeding and thrombosis

    Science.gov (United States)

    Kaczmarski, Jacek; Pacholewicz, Jerzy; Zakliczynski, Michal; Gasior, Mariusz; Zembala, Marian

    2015-01-01

    Mechanical circulatory support (MCS) is an umbrella term describing the various technologies used in both short- and long-term management of patients with either end-stage chronic heart failure (HF) or acute HF. Most often, MCS has emerged as a bridge to transplantation, but more recently it is also used as a destination therapy. Mechanical circulatory support includes left ventricular assist device (LVAD) or bi-ventricular assist device (Bi-VAD). Currently, 2- to 3-year survival in carefully selected patients is much better than with medical therapy. However, MCS therapy is hampered by sometimes life-threatening complications including bleeding and device thrombosis. Von Willebrand factor (vWF) has two major functions in haemostasis. First, it plays a crucial role in platelet-subendothelium adhesion and platelet-platelet interactions (aggregation). Second, it is the carrier of factor VIII (FVIII) in plasma. Von Willebrand factor prolongs FVIII half-time by protecting it from proteolytic degradation. It delivers FVIII to the site of vascular injury thus enhancing haemostatic process. On one hand, high plasma levels of vWF have been associated with an increased risk of thrombosis. On the other, defects or deficiencies of vWF underlie the inherited von Willebrand disease or acquired von Willebrand syndrome. Here we review the pathophysiology of thrombosis and bleeding associated with vWF. PMID:26702279

  18. Perturbation analysis of internal balancing for lightly damped mechanical systems with gyroscopic and circulatory forces

    Science.gov (United States)

    Blelloch, P. A.; Mingori, D. L.; Wei, J. D.

    1987-01-01

    Approximate expressions are developed for internally balanced singular values corresponding to the modes of mechanical systems with gyroscopic forces, light damping, and small circulatory forces. A brief overview is first given of the balanced realization model reduction method, including a discussion of recent work. The models considered are defined, and a perturbation analysis is used to show that the modal representation becomes asymptotically balanced as damping reduces to zero. The approximate balanced singular values are calculated, and a simple example of a flexible, dual-spin spacecraft is given as an illustration of the results.

  19. Burden of Circulatory System Diseases and Ignored Barriers ofKnowledge Translation

    Directory of Open Access Journals (Sweden)

    Hamed-Basir Ghafouri

    2012-10-01

    Full Text Available Circulatory system disease raise third highest disability-adjusted life years among Iranians and ischemic cardiac diseases are main causes for such burden. Despite available evidences on risk factors of the disease, no effective intervention was implemented to control and prevent the disease. This paper non-systematically reviews available literature on the problem, solutions, and barriers of implementation of knowledge translation in Iran. It seems that there are ignored factors such as cultural and motivational issues in knowledge translation interventions but there are hopes for implementation of started projects and preparation of students as next generation of knowledge transferors.

  20. Noninvasive optoacoustic system for rapid diagnosis and management of circulatory shock

    Science.gov (United States)

    Petrov, Irene Y.; Kinsky, Michael; Petrov, Yuriy; Petrov, Andrey; Henkel, S. N.; Seeton, Roger; Esenaliev, Rinat O.; Prough, Donald S.

    2013-03-01

    Circulatory shock can lead to death or severe complications, if not promptly diagnosed and effectively treated. Typically, diagnosis and management of circulatory shock are guided by blood pressure and heart rate. However, these variables have poor specificity, sensitivity, and predictive value. Early goal-directed therapy in septic shock patients, using central venous catheterization (CVC), reduced mortality from 46.5% to 30%. However, CVC is invasive and complication-prone. We proposed to use an optoacoustic technique for noninvasive, rapid assessment of peripheral and central venous oxygenation. In this work we used a medical grade optoacoustic system for noninvasive, ultrasound image-guided measurement of central and peripheral venous oxygenation. Venous oxygenation during shock declines more rapidly in the periphery than centrally. Ultrasound imaging of the axillary [peripheral] and internal jugular vein [central] was performed using the Vivid e (GE Healthcare). We built an optoacoustic interface incorporating an optoacoustic transducer and a standard ultrasound imaging probe. Central and peripheral venous oxygenations were measured continuously in healthy volunteers. To simulate shock-induced changes in central and peripheral oxygenation, we induced peripheral vasoconstriction in the upper extremity by using a cooling blanket. Central and peripheral venous oxygenations were measured before (baseline) and after cooling and after rewarming. During the entire experiment, central venous oxygenation was relatively stable, while peripheral venous oxygenation decreased by 5-10% due to cooling and recovered after rewarming. The obtained data indicate that noninvasive, optoacoustic measurements of central and peripheral venous oxygenation may be used for diagnosis and management of circulatory shock with high sensitivity and specificity.

  1. Mock circulatory system for the evaluation of left ventricular assist devices, endoluminal prostheses, and vascular diseases.

    Science.gov (United States)

    Legendre, Daniel; Fonseca, Jeison; Andrade, Aron; Biscegli, José Francisco; Manrique, Ricardo; Guerrino, Domingos; Prakasan, Akash Kuzhiparambil; Ortiz, Jaime Pinto; Lucchi, Julio Cesar

    2008-06-01

    A new digital computer mock circulatory system has been developed in order to replicate the physiologic and pathophysiologic characteristics of the human cardiovascular system. The computer performs the acquisition of pressure, flow, and temperature in an open loop system. A computer program has been developed in Labview programming environment to evaluate all these physical parameters. The acquisition system was composed of pressure, flow, and temperature sensors and also signal conditioning modules. In this study, some results of flow, cardiac frequencies, pressures, and temperature were evaluated according to physiologic ventricular states. The results were compared with literature data. In further works, performance investigations will be conducted on a ventricular assist device and endoprosthesis. Also, this device should allow for evaluation of several kinds of vascular diseases. PMID:18422796

  2. Non-Intrusive Device for Real-Time Circulatory System Assessment with Advanced Signal Processing Capabilities

    Science.gov (United States)

    Pinheiro, E.; Postolache, O.; Girão, P.

    2010-01-01

    This paper presents a device that uses three cardiography signals to characterize several important parameters of a subject's circulatory system. Using electrocardiogram, finger photoplethysmogram, and ballistocardiogram, three heart rate estimates are acquired from beat-to-beat time interval extraction. Furthermore, pre-ejection period, pulse transit time (PTT), and pulse arrival time (PAT) are computed, and their long-term evolution is analyzed. The system estimates heart rate variability (HRV) and blood pressure variability (BPV) from the heart rate and PAT time series, to infer the activity of the cardiac autonomic system. The software component of the device evaluates the frequency content of HRV and BPV, and also their fractal dimension and entropy, thus providing a detailed analysis of the time series' regularity and complexity evolution, to allow personalized subject evaluation.

  3. Assessment of left heart and pulmonary circulation flow dynamics by a new pulsed mock circulatory system

    Science.gov (United States)

    Tanné, David; Bertrand, Eric; Kadem, Lyes; Pibarot, Philippe; Rieu, Régis

    2010-05-01

    We developed a new mock circulatory system that is able to accurately simulate the human blood circulation from the pulmonary valve to the peripheral systemic capillaries. Two independent hydraulic activations are used to activate an anatomical-shaped left atrial and a left ventricular silicon molds. Using a lumped model, we deduced the optimal voltage signals to control the pumps. We used harmonic analysis to validate the experimental pulmonary and systemic circulation models. Because realistic volumes are generated for the cavities and the resulting pressures were also coherent, the left atrium and left ventricle pressure-volume loops were concordant with those obtained in vivo. Finally we explored left atrium flow pattern using 2C-3D+T PIV measurements. This gave a first overview of the complex 3D flow dynamics inside realistic left atrium geometry.

  4. Usefulness of extracorporeal membrane oxygenation using double roller pumps in a low body weight newborn: A novel strategy for mechanical circulatory support in an infant

    Directory of Open Access Journals (Sweden)

    Keisuke Nakanishi

    2016-01-01

    Full Text Available Extracorporeal membrane oxygenation (ECMO with a centrifugal pump requires a certain flow rate; therefore, its application for low body weight infants is frequently accompanied by oxygenator membrane malfunction and/or inadequate perfusion. To prevent low-flow associated complications, we report a case in which a novel system of dual roller pumps was used. A baby girl with a body mass index 0.25 m 2 , who experienced difficulty weaning from cardiopulmonary bypass after a Norwood-like operation, required an ECMO. Concerns for the tube lifespan reduction due to roller pump friction led to the use of a double roller pump circulation. The termination of ECMO during tube exchange is not needed, because circulation is maintained by another roller pump. The novel strategy of ECMO with double roller pumps will allow low perfusion rate to provide adequate circulatory support for low body weight patients.

  5. Stability of circulatory elastic systems in the presence of magnetic damping.

    Science.gov (United States)

    Smith, T. E.; Herrmann, G.

    1971-01-01

    The effect of a type of magnetic damping on the stability of equilibrium of some circulatory elastic systems is examined. A simple system with two degrees of freedom is considered first, and a destabilization is found to be caused by the magnetic field. The nature of the destabilization, however, is not identical to that caused by internal viscous damping. The differences and similarities between the two effects are discussed, and the results are also compared with those of linear external viscous damping. A continuous cantilever bar subjected to a follower force at its free end is then examined. It is found that the critical load is independent of the strength of the magnetic field, and is considerably lower than the corresponding critical load in the absence of a magnetic field. Finally, the continuous cantilever is treated approximately by Galerkin's procedure and also by using a two-degree-of-freedom model of the cantilever; the results obtained are qualitatively the same.

  6. Development and Validation of a Two-Tier Instrument to Examine Understanding of Internal Transport in Plants and the Human Circulatory System

    Science.gov (United States)

    Wang, Jing-Ru

    2004-01-01

    This study is intended to develop an assessment instrument to investigate students' understandings about internal transport in plants and human circulatory system. A refined process of a two-tier diagnostic test was used to develop the instrument. Finally, three versions of the Internal Transport in Plants and the Human Circulatory System test…

  7. Numerical Models of Human Circulatory System under Altered Gravity: Brain Circulation

    Science.gov (United States)

    Kim, Chang Sung; Kiris, Cetin; Kwak, Dochan; David, Tim

    2003-01-01

    A computational fluid dynamics (CFD) approach is presented to model the blood flow through the human circulatory system under altered gravity conditions. Models required for CFD simulation relevant to major hemodynamic issues are introduced such as non-Newtonian flow models governed by red blood cells, a model for arterial wall motion due to fluid-wall interactions, a vascular bed model for outflow boundary conditions, and a model for auto-regulation mechanism. The three-dimensional unsteady incompressible Navier-Stokes equations coupled with these models are solved iteratively using the pseudocompressibility method and dual time stepping. Moving wall boundary conditions from the first-order fluid-wall interaction model are used to study the influence of arterial wall distensibility on flow patterns and wall shear stresses during the heart pulse. A vascular bed modeling utilizing the analogy with electric circuits is coupled with an auto-regulation algorithm for multiple outflow boundaries. For the treatment of complex geometry, a chimera overset grid technique is adopted to obtain connectivity between arterial branches. For code validation, computed results are compared with experimental data for steady and unsteady non-Newtonian flows. Good agreement is obtained for both cases. In sin-type Gravity Benchmark Problems, gravity source terms are added to the Navier-Stokes equations to study the effect of gravitational variation on the human circulatory system. This computational approach is then applied to localized blood flows through a realistic carotid bifurcation and two Circle of Willis models, one using an idealized geometry and the other model using an anatomical data set. A three- dimensional anatomical Circle of Willis configuration is reconstructed from human-specific magnetic resonance images using an image segmentation method. The blood flow through these Circle of Willis models is simulated to provide means for studying gravitational effects on the brain

  8. Relations of Cognitive and Motivational Variables with Students' Human Circulatory System Achievement in Traditional and Learning Cycle Classrooms

    Science.gov (United States)

    Sadi, Özlem; Çakiroglu, Jale

    2014-01-01

    This study is aimed at investigating the relationships among students' relevant prior knowledge, meaningful learning orientation, reasoning ability, self-efficacy, locus of control, attitudes toward biology and achievement with the human circulatory system (HCS) using the learning cycle (LC) and the traditional classroom setting. The study…

  9. Students' Visualization of Diagrams Representing the Human Circulatory System: The Use of Spatial Isomorphism and Representational Conventions

    Science.gov (United States)

    Cheng, Maurice M. W.; Gilbert, John K.

    2015-01-01

    This study investigated students' interpretation of diagrams representing the human circulatory system. We conducted an interview study with three students aged 14-15 (Year 10) who were studying biology in a Hong Kong school. During the interviews, students were asked to interpret diagrams and relationships between diagrams that represented…

  10. Effect of 5E Instructional Model in Student Success in Primary School 6th Year Circulatory System Topic

    Science.gov (United States)

    Cardak, Osman; Dikmenli, Musa; Saritas, Ozge

    2008-01-01

    The aim of this study is to research the effect of the 5E instructional model on primary (sixth grade) student success during the circulatory system unit. This study was conducted with 38 students in two different classes by the same researcher in 2006-2007. One of the classes was assigned as the control group and the other as the experimental…

  11. The Contribution of Conceptual Change Texts Accompanied by Concept Mapping to Students' Understanding of the Human Circulatory System.

    Science.gov (United States)

    Sungur, Semra; Tekkaya, Ceren; Geban, Omer

    2001-01-01

    Investigates the contribution of conceptual change texts accompanied by concept mapping instruction to 10th-grade students' understanding of the human circulatory system. Indicates that the conceptual change texts accompanied by concept mapping instruction produced a positive effect on students' understanding of concepts. Concludes that students…

  12. The main issues and the ways of improvement of health care for patients with diseases of the circulatory system

    OpenAIRE

    Sazanova G.Yu.

    2014-01-01

    Regulations and publications on the provision of quality health care for patients with diseases of the circulatory system of the native scientists have been studied. The majority of the issues concerns the disorganization of health care standards: the uneven distribution of diagnostic resources mostly in the hospitals and preventive health care organizations. The proposed ways to improve the patient care have been analyzed.

  13. Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice.

    Science.gov (United States)

    Frebel, Helge; Nindl, Veronika; Schuepbach, Reto A; Braunschweiler, Thomas; Richter, Kirsten; Vogel, Johannes; Wagner, Carsten A; Loffing-Cueni, Dominique; Kurrer, Michael; Ludewig, Burkhard; Oxenius, Annette

    2012-12-17

    The inhibitory programmed death 1 (PD-1)-programmed death ligand 1 (PD-L1) pathway contributes to the functional down-regulation of T cell responses during persistent systemic and local virus infections. The blockade of PD-1-PD-L1-mediated inhibition is considered as a therapeutic approach to reinvigorate antiviral T cell responses. Yet previous studies reported that PD-L1-deficient mice develop fatal pathology during early systemic lymphocytic choriomeningitis virus (LCMV) infection, suggesting a host protective role of T cell down-regulation. As the exact mechanisms of pathology development remained unclear, we set out to delineate in detail the underlying pathogenesis. Mice deficient in PD-1-PD-L1 signaling or lacking PD-1 signaling in CD8 T cells succumbed to fatal CD8 T cell-mediated immunopathology early after systemic LCMV infection. In the absence of regulation via PD-1, CD8 T cells killed infected vascular endothelial cells via perforin-mediated cytolysis, thereby severely compromising vascular integrity. This resulted in systemic vascular leakage and a consequential collapse of the circulatory system. Our results indicate that the PD-1-PD-L1 pathway protects the vascular system from severe CD8 T cell-mediated damage during early systemic LCMV infection, highlighting a pivotal physiological role of T cell down-regulation and suggesting the potential development of immunopathological side effects when interfering with the PD-1-PD-L1 pathway during systemic virus infections. PMID:23230000

  14. Mechanical circulatory treatment of advanced heart failure

    DEFF Research Database (Denmark)

    Løgstrup, Brian B; Vase, Henrik; Gjedsted, Jakob;

    2016-01-01

    Heart failure is one of the most common causes of morbidity and mortality worldwide. When patients cease to respond adequately to optimal medical therapy mechanical circulatory support has been promising. The advent of mechanical circulatory support devices has allowed significant improvements in...... patient survival and quality of life for those with advanced or end-stage heart failure. We provide a general overview of current mechanical circulatory support devices encompassing options for both short- and long-term ventricular support....

  15. 38 CFR 4.62 - Circulatory disturbances.

    Science.gov (United States)

    2010-07-01

    ... FOR RATING DISABILITIES Disability Ratings The Musculoskeletal System § 4.62 Circulatory disturbances. The circulatory disturbances, especially of the lower extremity following injury in the popliteal... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Circulatory...

  16. Development of an in-vitro circulatory system with known resistance and capacitance

    Science.gov (United States)

    Offerdahl, C. D.; Schaub, J. D.; Koenig, S. C.; Swope, R. D.; Ewert, D. L.; Convertino, V. A. (Principal Investigator)

    1996-01-01

    An in-vitro (hydrodynamic) model of the circulatory system was developed. The model consisted of a pump, compliant tubing, and valves for resistance. The model is used to simulate aortic pressure and flow. These parameters were measured using a Konigsburg Pressure transducer and a Triton ART2 flow probe. In addition, venous pressure and flow were measured on the downstream side of the resistance. The system has a known compliance and resistance. Steady and pulsatile flow tests were conducted to determine the resistance of the model. A static compliance test was used to determine the compliance of the system. The aortic pressure and flow obtained from the hydrodynamic model will be used to test the accuracy of parameter estimation models such as the 2-element and 4-element Windkessel models and the 3-element Westkessel model. Verifying analytical models used in determining total peripheral resistance (TPR) and systemic arterial compliance (SAC) is important because it provides insight into hemodynamic parameters that indicate baroreceptor responsiveness to situations such as changes in gravitational acceleration.

  17. PERIPHERAL VENO-ARTERIAL ECMO AS MECHANICAL CIRCULATORY SUPPORT BEFORE HEART TRANSPLANTATION

    OpenAIRE

    E. A. Spirina; R. S. Saitgareev; D. V. Shumakov; V. M. Zakharevitch; V. V. Slobodyannik; M. G. Minina; V. V. Pchelnikov; O. A. Eremeeva; P. G. Lavrenov

    2013-01-01

    Aim of our clinical study was evaluation own initial experience of high-urgency ortotopic heart transplantation (OHT) in recipients, who were bridged on peripheral Vena-Arterial Extracorporeal Membrane Oxygenation (VA ECMO). Materials and methods. In this study was included 17 patients (14/3 M/F, age 16–66 (40.1 ± 4.2 yrs)) who underwent OHT while on peripheral ECMO support. In all cases we used peripheral surgical can- nulation technique via femoral vessels – arterial cannula 15–19 Fr, venou...

  18. Peristaltic flow in non-uniform vessels of the micro-circulatory system

    CERN Document Server

    Maiti, S

    2013-01-01

    Of concern in the paper is generalized a theoretical study concerning the peristaltic flow of blood in the micro-circulatory system. The vessel is considered to be of non-uniform cross-section and blood to be a non-Newtonian fluid. The progressive wave front of the peristaltic flow is supposed sinusoidal/straight section dominated (SSD) (expansion/contraction type); Reynolds number is considered to be small with reference to the flow of physiological fluids. The non-Newtonian behaviour of blood is illustrated by considering the Herschel-Bulkley fluid model. The objective of the study has been to examine the effect of the effects of amplitude ratio, mean pressure gradient, yield stress and the power law index on the velocity distribution, wall shear stress, streamline pattern and trapping. Considerable quantitative differences between the results obtained for transport in two dimensional channel and an axisymmetric circular tube are noticed. The study shows that peristaltic pumping, flow velocity and wall shea...

  19. Ventricular septal rupture complicating acute myocardial infarction in the modern era with mechanical circulatory support: a single center observational study.

    Science.gov (United States)

    Liebelt, Jared J; Yang, Yuanquan; DeRose, Joseph J; Taub, Cynthia C

    2016-01-01

    Ventricular septal rupture (VSR) is a rare but devastating complication after acute myocardial infarction (AMI). While the incidence has decreased, the mortality rate from VSR has remained extremely high. The use of mechanical circulatory support with intra-aortic balloon pump (IABP) and extracorporal membrane oxygenation (ECMO) may be useful in providing hemodynamic stability and time for myocardial scarring. However, the optimal timing for surgical repair remains an enigma. Retrospective analysis of 14 consecutive patients diagnosed with VSR after AMI at Montefiore Medical Center between January 2009 and June 2015. A chart review was performed with analysis of baseline characteristics, hemodynamics, imaging, percutaneous interventions, surgical timing, and outcomes. The survival group had a higher systolic BP (145 vs 98, p<0.01), higher MAP (96 vs 76, p=0.03), and lower HR (75 vs 104, p=0.05). Overall surgical timing was 6.5 ± 3.7 days after indexed myocardial infarction with a significant difference between survivors and non-survivors (9.8 vs 4.3, p=0.01). The number of pre-operative days using IABP was longer in survivors (6.5 vs 3.2, p=0.36) as was post-operative ECMO use (4.5 vs 2 days, p=0.35). The overall 30-day mortality was 71.4% with a 60% surgical mortality rate. Hemodynamics at the time of presentation and a delayed surgical approach of at least 9 days showed significant association with improved survival. Percutaneous coronary intervention (PCI) was more common in non-survivors. The use of IABP in the pre-operative period and post-operative ECMO use likely provide a survival benefit. PMID:27073732

  20. Single and combined effects of air pollutants on circulatory and respiratory system-related mortality in Belgrade, Serbia.

    Science.gov (United States)

    Stojić, Svetlana Stanišić; Stanišić, Nemanja; Stojić, Andreja; Šoštarić, Andrej

    2016-01-01

    The aim of this study was to investigate the association between short- and long-term exposure to particulate matter (PM10), nitrogen dioxide (NO2), sulfur dioxide (SO2), and soot and mortality attributed to circulatory and respiratory diseases in Belgrade area (Serbia). The analyzed data set comprised results of regular pollutant monitoring and corresponding administrative records on frequency of daily mortality in the period 2009-2014. Nonlinear exposure-response dependencies and delayed effects of temperature were examined by means of distributed lag nonlinear models. The air pollutant loadings and circulatory system-related death rates in Belgrade area are among the highest in Europe. Data demonstrated that excess risk of death with short-term exposure to elevated concentrations of PM10, SO2, and soot was not significant, whereas marked effect size estimates for exposure over 90 d preceding mortality were found. The influence of chronic exposure was shown to be greater for respiratory than circulatory system-related mortality. When stratified by age and gender, higher risk was noted for male individuals below the age of 65 years. PMID:26699658

  1. Dose-response relationship analysis for cancer and circulatory system disease mortality risks among uranium miners

    International Nuclear Information System (INIS)

    The relation between lung cancer risk and radon exposure has been clearly established, especially from the studies on uranium miner cohorts. But the association between radon exposure and extrapulmonary cancers and non-cancer diseases remains not well known. Moreover, the health risks associated with the other mining-related ionizing radiation exposures are still under consideration. The aim of this thesis is to contribute to the estimation of the radio-induced health risks at low-doses through the analysis of the kidney cancer and Circulatory System Disease (CSD) mortality risks among uranium miners. Kidney cancer mortality risk analyses were performed from the French cohort of uranium miners (n=5086; follow-up period: 1946-2007), the post-55 cohort (n=3,377; follow-up period: 1957-2007) and the German cohort of the Wismut (n=58,986; follow-up period: 1946-2003) which included 24, 11 and 174 deaths from kidney cancer, respectively. The exposures to radon and its short-lived progeny (expressed in Working Level Month WLM), to uranium ore dust (kBqh.m-3) and to external gamma rays (mSv) were estimated for each miners and the equivalent kidney dose was calculated. The dose-response relation was refined considering two responses: the instantaneous risk of kidney cancer mortality (corresponding to the classical analysis, Cause specific Hazard Ratio (CSHR) estimated with the Cox model) and its occurrence probability during the followup (Sub-distribution Hazard Ratio (SHR) estimated with the Fine and Gray model). An excess of kidney cancer mortality was observed only in the French cohort (SMR = 1.62 CI95%[1.04; 2.41]). In the Wismut cohort, a decrease of the kidney cancer mortality was observed (0.89 [0.78; 0.99]). For these three cohorts, the occupational radiological exposures (or the equivalent kidney dose) were significantly associated neither with the risk of kidney cancer mortality (e.g. CSHRWismut-radon/100 WLM=1.023 [0.993; 1.053]), nor with its occurrence

  2. Mechanical Circulatory Assist Devices

    OpenAIRE

    Park, Sang B.; Magovern, George J.; Christlieb, Ignacio Y.; Kao, Race L.

    1987-01-01

    Cardiogenic shock occurs in about 10% of the 1.5 million patients who suffer myocardial infarction and in approximately 1% of the 200,000 patients who undergo open-heart surgery each year. The ventricular assist device decreases the workload of the failing ventricles and increases the blood flow through the coronary system. Recovery of failing myocardium after mechanical circulatory assistance has been well documented; however, the mechanisms that contribute to the recovery of a failing heart...

  3. Plasma FITC-dextran exchange between the primary and secondary circulatory systems in the Atlantic cod, Gadus Morhua

    DEFF Research Database (Denmark)

    Fischer, Claes; Steffensen, John Fleng

    2008-01-01

    Fluorescein isothiocyanate dextran (FITC-dextran) exchange between the primary (PCS) and secondary (SCS) circulatory systems in the Atlantic cod, Gadus morhua (Linnaeus, 1752), were studied using 20-kDa (n = 4) and 500-kDa (n = 4) FITC-dextran. In order to give a qualitative perspective of the...... injected 500-kDa FITC-dextran was also examined, and it was observed that of the 500-kDa FITC-dextran lost from the primary and secondary vascular systems, 63.0 +/- 9.2% could be recovered from the liver....

  4. [THE CHARACTERISTIC OF SOMATOTYPE AND FUNCTIONAL STATE OF CIRCULATORY SYSTEM OF STUDENT YOUTH OF THE NORTHEAST OF RUSSIA].

    Science.gov (United States)

    Timofeieva, A V; Klimova, T M; Mikhailova, A E; Zakharova, R N; Vinokurova, S P; Timofeiev, L F

    2015-01-01

    The article considers results of single-step study in random sampling of female students of the M.K. Ammosov north-east federal university (n=456). The study was carried out to investigate somatotype and functional state of circulatory system. The standard technique was applied to measure height, body mass, chest circumference, level of arterial pressure and rate of heart beats. The type of somatotype was established using Pignet index. The tone of vegetative system was determined using Kérdö index. The adaptation potential of circulatory system was determined using functional changes index. The results of study established that in 61% of examined female students the type of constitution corresponds to normosthenic one. The percentage of persons with asthenic and hypersthenic type of constitution amounted to 27% and 12% correspondingly. The signs of increasing oftone ofsympathetic nervous system are observed in 89% of girls. The functional condition of circulatory system is evaluated as "tension of adaptation mechanisms" that is apparently related to period of adaptation to new conditions. The prolonged preservation of such states results in exhaustion offunctional resources of organism and can promote development of diseases. In conditions of impacting of unfavorable ecological factors the deconditionning disorders can significantly contribute to health disturbances and decreasing of life quality. To preserve youth's health during period of education the comprehensive strategy is to be implemented such components as dynamic monitoring of health, organization of adequate diet, explanation of necessity of observance of sleep and rest pattern, development of conditions for active aerobic physical exertion and activities on correction of risk factors of development of diseases are to be included. PMID:26987173

  5. Infectious and inflammatory disorders of the circulatory system as risk factors for stroke in Saudi children

    International Nuclear Information System (INIS)

    Objective was to report on the role of infectious and inflammatory disorders as risk factors for stroke in a prospective and retrospective cohort of Saudi children. Children, who presented with stroke, were evaluated at the Division of Pediatric Neurology or admitted to King Khalid University Hospital, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia during the periods July 1992 to February 2001 (retrospective study) and February 2001 to March 2003 (prospective study). Investigations for suspected cases included haemostatic assays, microbiological and serological tests. Neuroimaging included cranial CT, MRI magnetic resonance angiography (MRA), magnetic resonance venography (MRV) and single photon emission computed tomography (SPECT) brain scan. Of the 104 Saudi children with stroke, seen during the combined study periods of 10 years and 7 months, infectious and inflammatory disorders of the circulatory systems were identified risk factors in 18 (17.3%). Five children had stroke following acute bacterial meningitis at ages ranging between 5-21 months. The causative organism was identified in 3 of them and consisted of Haemophilus influenza (in a 5-months-old girl), Streptococcus pneumonia (in a 21-months-old girl complicated by subdural empyema and sinovenous thrombosis), and Staphylococcus aureus in a 6-months-old boy who had an underlying chronic granulomatous disease. Unspecified meningitis/meningoencephalitis affected 4 patients, whereas 3 children had an underlying congenital infection as a cause for their stroke. Two of the latter 3 children were diagnosed to have congenital toxoplasmosis, and the third had congenital rubella syndrome. Two girls had stroke following septicemia at ages of one and 2 months. Neurobrucellosis caused stroke in 2 boys at the ages of 4 1/2 and 4 years. In both patients, neuroimaging revealed lacunar and other infects involving mainly the deep cerebral nuclei, secondary to occlusion of small penetrating end

  6. THE IMPACT OF THE CONCEPT MAPS USED FOR OUR CIRCULATORY SYSTEM ON STUDENTS ACADEMIC SUCCESS

    OpenAIRE

    ÇAKMAK, Mürşet; Hasan GÜRBÜZ; Haci KAPLAN

    2012-01-01

    This study is aimed to investigate effects of teaching “Our Circulatory System”, which is one of the subjects in Science Technology Education curriculum, with concept maps on learning level of students comparing with the traditional methods. The study was carried out in a primary school in Diyarbakır, in 2011, and it is an experimental study with a pre-post test control group. The test group included 80 (N=80) 6th year students. Control group was taught using the traditional methods while tes...

  7. The human heart and the circulatory system as an interesting interdisciplinary topic in lessons of physics and biology

    Science.gov (United States)

    Volná, M.; Látal, F.; Kubínek, R.; Richterek, L.

    2014-01-01

    Many topics which are closely related can be found in the national curriculum of the Czech Republic for physics and biology. One of them is the heart and the circulatory system in the human body. This topic was examined cross curriculum, a teaching module was created and the topic was chosen for our research. The task was to determine if the students of bachelor study are aware of connections between physics and biology within this topic and whether we can help them effectively to describe the corresponding physics phenomena in the human body connected, for example, with a heart attack or with the measurement of blood pressure. In this paper, the heart and the circulatory system are presented as suitable topics for an interdisciplinary teaching module which includes both theoretical and experimental parts. The module was evaluated by a group of first-year undergraduate students of physics at the Faculty of Science, Palacký University. The acquired knowledge was compared with another control group through a test. The highest efficiency of the module was evaluated on the basis of questions that covered the calculation problems.

  8. The human heart and the circulatory system as an interesting interdisciplinary topic in lessons of physics and biology

    International Nuclear Information System (INIS)

    Many topics which are closely related can be found in the national curriculum of the Czech Republic for physics and biology. One of them is the heart and the circulatory system in the human body. This topic was examined cross curriculum, a teaching module was created and the topic was chosen for our research. The task was to determine if the students of bachelor study are aware of connections between physics and biology within this topic and whether we can help them effectively to describe the corresponding physics phenomena in the human body connected, for example, with a heart attack or with the measurement of blood pressure. In this paper, the heart and the circulatory system are presented as suitable topics for an interdisciplinary teaching module which includes both theoretical and experimental parts. The module was evaluated by a group of first-year undergraduate students of physics at the Faculty of Science, Palacký University. The acquired knowledge was compared with another control group through a test. The highest efficiency of the module was evaluated on the basis of questions that covered the calculation problems. (paper)

  9. NASA Models of Space Radiation Induced Cancer, Circulatory Disease, and Central Nervous System Effects

    Science.gov (United States)

    Cucinotta, Francis A.; Chappell, Lori J.; Kim, Myung-Hee Y.

    2013-01-01

    The risks of late effects from galactic cosmic rays (GCR) and solar particle events (SPE) are potentially a limitation to long-term space travel. The late effects of highest concern have significant lethality including cancer, effects to the central nervous system (CNS), and circulatory diseases (CD). For cancer and CD the use of age and gender specific models with uncertainty assessments based on human epidemiology data for low LET radiation combined with relative biological effectiveness factors (RBEs) and dose- and dose-rate reduction effectiveness factors (DDREF) to extrapolate these results to space radiation exposures is considered the current "state-of-the-art". The revised NASA Space Risk Model (NSRM-2014) is based on recent radio-epidemiology data for cancer and CD, however a key feature of the NSRM-2014 is the formulation of particle fluence and track structure based radiation quality factors for solid cancer and leukemia risk estimates, which are distinct from the ICRP quality factors, and shown to lead to smaller uncertainties in risk estimates. Many persons exposed to radiation on earth as well as astronauts are life-time never-smokers, which is estimated to significantly modify radiation cancer and CD risk estimates. A key feature of the NASA radiation protection model is the classification of radiation workers by smoking history in setting dose limits. Possible qualitative differences between GCR and low LET radiation increase uncertainties and are not included in previous risk estimates. Two important qualitative differences are emerging from research studies. The first is the increased lethality of tumors observed in animal models compared to low LET radiation or background tumors. The second are Non- Targeted Effects (NTE), which include bystander effects and genomic instability, which has been observed in cell and animal models of cancer risks. NTE's could lead to significant changes in RBE and DDREF estimates for GCR particles, and the potential

  10. Long-term allergen exposure induces adipose tissue inflammation and circulatory system injury.

    Science.gov (United States)

    Jung, Chien-Cheng; Su, Huey-Jen

    2016-05-01

    The purpose of this study was to study whether allergen exposure can induce inflammation and lower the anti-inflammation levels in serum and in adipose tissues, and further develop cardiovascular injury. Our data showed that heart rate was significantly higher in the OVA-challenged mice compared to control mice. Moreover, there were higher expressions of pro-inflammation genes in the OVA-challenged mice in adipose tissues, and the expressions of anti-inflammation genes were lower. The levels of inflammation mediators were associated in serum and adipose tissues. The level of circulatory injury lactate dehydrogenase was significantly associated with the levels of E-selectin, resistin and adiponectin in the serum. The hematoxylin and eosin and immunohistochemistry stains indicated the OVA-challenged mice had higher levels of inflammation. In summary, the current study demonstrated allergen exposure can cause cardiovascular injury, and inflammatory mediators in adipose tissues play an important role in the pathogenesis of cardiovascular injury. PMID:27004794

  11. [Preoperative preparation of pregnant with hypertension according to state of the autonomic nervous system and circulatory system].

    Science.gov (United States)

    Gur'ianov, V A; Tolmachev, G N; Volodin, A V; Marichik, N V; Nemirovskiĭ, V B; Pivovarova, G M; Shepetovskaia, N L

    2010-01-01

    Pregnancy in patients with hypertension is considered in the spotlight of creation of general adaptation syndrome. According to evidence, when a stable hypertension in pregnant patients with hyper- and eukinetic types of haemodynamics is observed, the response of circulatory system and body fluid compartments has a moderate difference with normal. In pregnant patients with hypertension and a hypokinetic type of haemodynamics and pregnant patients with gestosis developed against the background of eukinetic type of hypertension, a physiological decrease of total peripheral resistance (TPR) is absent, which contributes into interstitial hyperhydration. In pregnant patients with gestosis developed against the background of hypokinetic type of haemodynamics, a pathological rise of TPR occurs, which is followed with a more significant interstitial hyperhydration. A differentiated preoperative preparation of pregnant with hypertension with the calcium antagonists and hydroxyethyl starch solution (130/0,4) favours the conversion of hyper- and hypokinetic types of haemodynamics to eukinetic, forms a physiological type of sympathicotonia and improves the water-salt metabolism. PMID:21400790

  12. THE IMPACT OF THE CONCEPT MAPS USED FOR OUR CIRCULATORY SYSTEM ON STUDENTS ACADEMIC SUCCESS

    Directory of Open Access Journals (Sweden)

    Mürşet ÇAKMAK

    2012-06-01

    Full Text Available This study is aimed to investigate effects of teaching “Our Circulatory System”, which is one of the subjects in Science Technology Education curriculum, with concept maps on learning level of students comparing with the traditional methods. The study was carried out in a primary school in Diyarbakır, in 2011, and it is an experimental study with a pre-post test control group. The test group included 80 (N=80 6th year students. Control group was taught using the traditional methods while test-group was trained with the concept maps. Data was collected using achievement test, which has 32 items and of which reliability co-efficient was 0,79. Research period lasted 5 weeks. The data collected was evaluated using SPSS-17. T-test analytical techniques were used to analyse. The significance level was considered as 0.05. As a result, teaching with the concept maps was found to affect students’ academic success at significant level. Some suggestions were made in the light of outcomes.

  13. Life Expectancy and Death by Diseases of the Circulatory System in Patients with Bipolar Disorder or Schizophrenia in the Nordic Countries

    OpenAIRE

    Laursen, Thomas Munk; Wahlbeck, Kristian; Hällgren, Jonas; Westman, Jeanette; Ösby, Urban; Alinaghizadeh, Hassan; Gissler, Mika; Nordentoft, Merete

    2013-01-01

    Objective Excess mortality from diseases and medical conditions (natural death) in persons with psychiatric disorders has been extensively reported. Even in the Nordic countries with well-developed welfare systems, register based studies find evidence of an excess mortality. In recent years, cardiac mortality and death by diseases of the circulatory system has seen a decline in all the Nordic countries, but a recent paper indicates that women and men in Denmark, Finland, and Sweden, who had b...

  14. Life expectancy and death by diseases of the circulatory system in patients with bipolar disorder or schizophrenia in the Nordic countries

    DEFF Research Database (Denmark)

    Laursen, Thomas Munk; Wahlbeck, Kristian; Hällgren, Jonas; Westman, Jeanette; Ösby, Urban; Alinaghizadeh, Hassan; Gissler, Mika; Nordentoft, Merete

    2013-01-01

    mortality and death by diseases of the circulatory system has seen a decline in all the Nordic countries, but a recent paper indicates that women and men in Denmark, Finland, and Sweden, who had been hospitalised for a psychotic disorder, had a two to three-fold increased risk of dying from a cardiovascular...... disease. The aim of this study was to compare the mortality by diseases of the circulatory system among patients with bipolar disorder or schizophrenia in the three Nordic countries Denmark, Sweden, and Finland. Furthermore, the aim was to examine and compare life expectancy among these patients. Cause......Excess mortality from diseases and medical conditions (natural death) in persons with psychiatric disorders has been extensively reported. Even in the Nordic countries with well-developed welfare systems, register based studies find evidence of an excess mortality. In recent years, cardiac...

  15. Viscoelasticity of blood and viscoelastic blood analogues for use in polydymethylsiloxane in vitro models of the circulatory system.

    Science.gov (United States)

    Campo-Deaño, Laura; Dullens, Roel P A; Aarts, Dirk G A L; Pinho, Fernando T; Oliveira, Mónica S N

    2013-01-01

    The non-Newtonian properties of blood are of great importance since they are closely related with incident cardiovascular diseases. A good understanding of the hemodynamics through the main vessels of the human circulatory system is thus fundamental in the detection and especially in the treatment of these diseases. Very often such studies take place in vitro for convenience and better flow control and these generally require blood analogue solutions that not only adequately mimic the viscoelastic properties of blood but also minimize undesirable optical distortions arising from vessel curvature that could interfere in flow visualizations or particle image velocimetry measurements. In this work, we present the viscoelastic moduli of whole human blood obtained by means of passive microrheology experiments. These results and existing shear and extensional rheological data for whole human blood in the literature enabled us to develop solutions with rheological behavior analogous to real whole blood and with a refractive index suited for PDMS (polydymethylsiloxane) micro- and milli-channels. In addition, these blood analogues can be modified in order to obtain a larger range of refractive indices from 1.38 to 1.43 to match the refractive index of several materials other than PDMS. PMID:24404022

  16. Application of a PExSim for modeling a POLVAD artificial heart and the human circulatory system with left ventricle assistance

    Science.gov (United States)

    Siewnicka, Alicja; Fajdek, Bartlomiej; Janiszowski, Krzysztof

    2010-01-01

    This paper presents a model of the human circulatory system with the possible addition of a parallel assist device, which was developed for the purpose of artificial heart monitoring. Information about an identification experiment of an extracorporeal ventricle assist device POLVAD is included. The modelling methods applied and the corresponding functional blocks in a PExSim package are presented. The results of the simulation for physiological conditions, left ventricle failure and pathological conditions with parallel assistance are included.

  17. A biplane roentgen videometry system for dynamic /60 per second/ studies of the shape and size of circulatory structures, particularly the left ventricle.

    Science.gov (United States)

    Ritman, E. L.; Sturm, E.; Wood, E. H.; Heintzen, P. H.

    1971-01-01

    A roentgen-television digital-computer technique and a display system developed for dynamic circulatory structure studies are described. Details are given for a videoroentgenographic setup which is used for obtaining biplane roentgen silhouettes of a left ventricle. A 60 per sec measurement of the shape and volume of angiographically outlined cardiac chambers can be made by this technique along with simultaneous ECG, pressure, and flow measurements accessible for real-time digital computer processing and analysis.

  18. Extension of the destabilization paradox to limit cycle amplitudes for a nonlinear self-excited system subject to gyroscopic and circulatory actions

    OpenAIRE

    Hervé, Benjamin; Sinou, Jean-Jacques; Mahé, Hervé; Jezequel, Louis

    2009-01-01

    This study aims at clarifying the phenomenological roots of an acoustical disturbance known as "clutch squeal noise". A nonlinear two-degrees-of-freedom model is introduced in order to illustrate some basic phenomena leading to self-generated vibrations. The damping of the system as well as both circulatory and gyroscopic actions are included in order to highlight their respective influence and the destabilization paradox. Results are obtained on the stability range of the equilibrium, the na...

  19. In-Series Versus In-Parallel Mechanical Circulatory Support for the Right Heart: A Simulation Study.

    Science.gov (United States)

    Hsu, Po-Lin; McIntyre, Madeleine; Boehning, Fiete; Dang, Weiguo; Parker, Jack; Autschbach, Rüdiger; Schmitz-Rode, Thomas; Steinseifer, Ulrich

    2016-06-01

    Right heart failure (RHF) is a serious health issue with increasing incidence and high mortality. Right ventricular assist devices (RVADs) have been used to support the end-stage failing right ventricle (RV). Current RVADs operate in parallel with native RV, which alter blood flow pattern and increase RV afterload, associated with high tension in cardiac muscles and long-term valve complications. We are developing an in-series RVAD for better RV unloading. This article presents a mathematical model to compare the effects of RV unloading and hemodynamic restoration on an overloaded or failing RV. The model was used to simulate both in-series (sRVAD) and in-parallel (pRVAD) (right atrium-pulmonary artery cannulation) support for severe RHF. The results demonstrated that sRVAD more effectively unloads the RV and restores the balance between RV oxygen supply and demand in RHF patients. In comparison to simulated pRVAD and published clinical and in silico studies, the sRVAD was able to provide comparable restoration of key hemodynamic parameters and demonstrated superior afterload and volume reduction. This study concluded that in-series support was able to produce effective afterload reduction and preserve the valve functionality and native blood flow pattern, eliminating complications associated with in-parallel support. PMID:26511211

  20. Association of sulfur dioxide exposure with circulatory system deaths in a medium-sized city in Brazil

    OpenAIRE

    C.T. Amancio; Nascimento, L.F.C.

    2012-01-01

    There is a demonstrable association between exposure to air pollutants and deaths due to cardiovascular diseases. The objective of this study was to estimate the effects of exposure to sulfur dioxide on mortality due to circulatory diseases in individuals 50 years of age or older residing in São José dos Campos, SP. This was a time-series ecological study for the years 2003 to 2007 using information on deaths due to circulatory disease obtained from Datasus reports. Data on daily levels of po...

  1. Clinical trial design and rationale of the Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy With HeartMate 3 (MOMENTUM 3) investigational device exemption clinical study protocol.

    Science.gov (United States)

    Heatley, Gerald; Sood, Poornima; Goldstein, Daniel; Uriel, Nir; Cleveland, Joseph; Middlebrook, Don; Mehra, Mandeep R

    2016-04-01

    The HeartMate 3 left ventricular assist system (LVAS; St. Jude Medical, Inc., formerly Thoratec Corporation, Pleasanton, CA) was recently introduced into clinical trials for durable circulatory support in patients with medically refractory advanced-stage heart failure. This centrifugal, fully magnetically levitated, continuous-flow pump is engineered with the intent to enhance hemocompatibility and reduce shear stress on blood elements, while also possessing intrinsic pulsatility. Although bridge-to-transplant (BTT) and destination therapy (DT) are established dichotomous indications for durable left ventricular assist device (LVAD) support, clinical practice has challenged the appropriateness of these designations. The introduction of novel LVAD technology allows for the development of clinical trial designs to keep pace with current practices. The prospective, randomized Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy With HeartMate 3 (MOMENTUM 3) clinical trial aims to evaluate the safety and effectiveness of the HeartMate 3 LVAS by demonstrating non-inferiority to the HeartMate II LVAS (also St. Jude Medical, Inc.). The innovative trial design includes patients enrolled under a single inclusion and exclusion criteria , regardless of the intended use of the device, with outcomes ascertained in the short term (ST, at 6 months) and long term (LT, at 2 years). This adaptive trial design includes a pre-specified safety phase (n = 30) analysis. The ST cohort includes the first 294 patients and the LT cohort includes the first 366 patients for evaluation of the composite primary end-point of survival to transplant, recovery or LVAD support free of debilitating stroke (modified Rankin score >3), or re-operation to replace the pump. As part of the adaptive design, an analysis by an independent statistician will determine whether sample size adjustment is required at pre-specified times during the study. A further 662

  2. Short-term Mechanical Circulatory Support with a Centrifugal Pump - Results of Peripheral Extracorporeal Membrane Oxygenator According to Clinical Situation

    OpenAIRE

    Lee, Woo Surng; Chee, Hyun Keun; Song, Meong Gun; Kim, Yo Han; Shin, Je Kyoun; Kim, Jun Seok; Lee, Song Am; Hwang, Jae Joon

    2011-01-01

    Background A peripheral extracorporeal membrane oxygenator (p-ECMO) has been developed to support patients who are dying due to a serious cardiopulmonary condition. This analysis was planned to define the clinical situation in which the patient benefits most from a p-ECMO. Material and Methods Between June 2007 and Aug 2009, a total of 41 adult patients used the p-ECMO. There were 23 males and 18 females (mean age 54.4±15.1 years). All patients had very unstable vital signs with hypoxia and c...

  3. Relationships between Digestive, Circulatory, and Urinary Systems in Portuguese Primary Textbooks

    Science.gov (United States)

    Carvalho, Graça S.; Clèment, Pierre

    2007-01-01

    In this study, 63 Portuguese primary schoolbooks (1920-2005) were analyzed. The analysis focused on text information (reference to blood absorption and association of the digestive system to other human systems) and on information from images (presence or absence of image "confusion" (when the sequence of the digestive tract is not…

  4. Contribution to the physical modeling of the circulatory system: optimization and evolution

    OpenAIRE

    Silva, Carla Alexandra de Castro Carvalho e

    2014-01-01

    Branched networks are ubiquitous in living systems. The dimensions and the geometry of these branched structures are key aspects of the efficiency of physiological processes. A resistive-capacitive model of an optimized pulsatile flow system based on Constructal Theory is presented, which aims to explain the performance of the human arterial tree. Optimal scaling laws for diameters and lengths emerged that are valid for dichotomous branching. The model together with data of the...

  5. Signaling at the cell surface in the circulatory and ventilatory systems

    CERN Document Server

    Thiriet, Marc

    2012-01-01

    The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 3 is devoted to the set of mediators of the cell surface, especially ion and molecular carriers and catalytic receptors that, once liganded and activated, initiat...

  6. Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice

    OpenAIRE

    Frebel, Helge; Nindl, Veronika; Schuepbach, Reto A; Braunschweiler, Thomas; Richter, Kirsten; Vogel, Johannes; Wagner, Carsten A.; Loffing-Cueni, Dominique; Kurrer, Michael; Ludewig, Burkhard; Oxenius, Annette

    2012-01-01

    The inhibitory programmed death 1 (PD-1)–programmed death ligand 1 (PD-L1) pathway contributes to the functional down-regulation of T cell responses during persistent systemic and local virus infections. The blockade of PD-1–PD-L1–mediated inhibition is considered as a therapeutic approach to reinvigorate antiviral T cell responses. Yet previous studies reported that PD-L1–deficient mice develop fatal pathology during early systemic lymphocytic choriomeningitis virus (LCMV) infection, suggest...

  7. 78 FR 55081 - Circulatory System Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2013-09-09

    ... (inductor) electromagnetically couples to the Sensor and allows the remote measurement of the resonant frequency of the inductive/capacitive (LC) circuit. This allows for wireless communication with the Sensor.... The system consists of the following: Implantable Sensor--The Pressure Sensor consists of a...

  8. Assessment of a continuous blood gas monitoring system in animals during circulatory stress

    Directory of Open Access Journals (Sweden)

    Renzulli Attilio

    2011-01-01

    Full Text Available Abstract Background The study was aimed to determine the measurement accuracy of The CDI™ blood parameter monitoring system 500 (Terumo Cardiovascular Systems Corporation, Ann Arbor MI in the real-time continuous measurement of arterial blood gases under different cardiocirculatory stress conditions Methods Inotropic stimulation (Dobutamine 2.5 and 5 μg/kg/min, vasoconstriction (Arginine-vasopressin 4, 8 and 16 IU/h, hemorrhage (-10%, -20%, -35%, and -50% of the theoretical volemia, and volume resuscitation were induced in ten swine (57.4 ± 10.7 Kg.Intermittent blood gas assessments were carried out using a routine gas analyzer at any experimental phase and compared with values obtained at the same time settings during continuous monitoring with CDI™ 500 system. The Bland-Altman analysis was employed. Results Bias and precision for pO2 were - 0.06 kPa and 0.22 kPa, respectively (r2 = 0.96; pCO2 - 0.02 kPa and 0.15 kPa, respectively; pH -0.001 and 0.01 units, respectively ( r2 = 0.96. The analysis showed very good agreement for SO2 (bias 0.04,precision 0.33, r2 = 0.95, Base excess (bias 0.04,precision 0.28, r2 = 0.98, HCO3 (bias 0.05,precision 0.62, r2 = 0.92,hemoglobin (bias 0.02,precision 0.23, r2 = 0.96 and K+ (bias 0.02, precision 0.27, r2 = 0.93. The sensor was reliable throughout the experiment during hemodynamic variations. Conclusions Continuous blood gas analysis with the CDI™ 500 system was reliable and it might represent a new useful tool to accurately and timely monitor gas exchange in critically ill patients. Nonetheless, our findings need to be confirmed by larger studies to prove its reliability in the clinical setting.

  9. High-frequency Doppler ultrasound transducer for the peripheral circulatory system

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Youngmin; Yang, Jeongwon; Kang, Uk; Kim, Guanghoon [Korea Electrotechnology Research Institute, Ansan (Korea, Republic of)

    2011-12-15

    A Doppler ultrasound transducer was designed and implemented to measure the blood flow velocity in tiny vessels near the skin of hands or feet. The geometric parameters of the transducer for defining the observation volume were derived and implemented with an acoustic window made of polystyrene. The observation volume designed in this study was located 6.5 mm from the transducer, which was comparable to the value predicted geometrically. The two-way insertion loss of the transducer was -11.3 dB on ultrasound frequency of 20 MHz, and the 3-dB bandwidth was approximately 2 MHz. In addition, the Doppler shift in the frequency measured by using a Doppler device composed of the transducer and a Doppler signal processing unit was proportional to the flow velocity generated by a homemade flowing system. Finally, we concluded that the transducer could be applied to measure the blood flow velocity in hands or feet.

  10. Numerical modeling of the fetal blood flow in the placental circulatory system

    Science.gov (United States)

    Shannon, Alexander; Gallucci, Sergio; Mirbod, Parisa

    2015-11-01

    The placenta is a unique organ of exchange between the growing fetus and the mother. It incorporates almost all functions of the adult body, acting as the fetal lung, digestive and immune systems, to mention a few. The exchange of oxygen and nutrients takes place at the surface of the villous tree. Using an idealized geometry of the fetal villous trees in the mouse placenta, in this study we performed 3D computational analysis of the unsteady fetal blood flow, gas, and nutrient transport over the chorionic plate. The fetal blood was treated as an incompressible Newtonian fluid, and the oxygen and nutrient were treated as a passive scalar dissolved in blood plasma. The flow was laminar, and a commercial CFD code (COMSOL Multiphysics) has been used for the simulation. COMSOL has been selected because it is multi-physics FEM software that allows for the seamless coupling of different physics represented by partial differential equations. The results clearly illustrate that the specific branching pattern and the in-plane curvature of the fetal villous trees affect the delivery of blood, gas and nutrient transport to the whole placenta.

  11. The influence of the winter North Atlantic Oscillation index on hospital admissions through diseases of the circulatory system in Lisbon, Portugal

    Science.gov (United States)

    Almendra, Ricardo; Santana, Paula; Vasconcelos, João; Silva, Giovani; Gonçalves, Fábio; Ambrizzi, Tércio

    2016-07-01

    The aim of this paper is to analyze the relationship between North Atlantic Oscillation (NAO), meteorological variables, air pollutants, and hospital admissions due to diseases of circulatory systems in Lisbon (Portugal) during winter months (2003-2012). This paper is one of the few studies analyzing the impact of NAO on health through its influence on thermal stress and air pollution and is the first to be conducted in Lisbon. This study uses meteorological data (synthetized into a thermal comfort index), air pollutant metrics, and the NAO index (all clustered in 10-day cycles to overcome daily variability of the NAO index). The relationship between morbidity, thermal comfort index, NAO index, and air pollutants was explored through several linear models adjusted to seasonality through a periodic function. The possible indirect effect between the NAO index and hospital admissions was tested, assuming that NAO (independent variable) is affecting hospital admissions (outcome variable) through thermal discomfort and/or pollution levels (tested as individual mediators). This test was conducted through causal mediation analysis and adjusted for seasonal variation. The results from this study suggest a possible indirect relationship between NAO index and hospital admissions. Although NAO is not significantly associated with hospital admissions, it is significantly associated with CO, PM2.5, NO, and SO2 levels, which in turn increase the probability of hospitalization. The discomfort index (built with temperature and relative humidity) is significantly associated with hospital admissions, but its variability is not explained by the NAO index. This study highlights the impacts of the atmospheric circulation patterns on health. Furthermore, understanding the influence of the atmospheric circulation patterns can support the improvement of the existing contingency plans.

  12. The peculiarities of formation of circulatory system pathology of evacuated adult population exposed to ionizing radiation on thyroid gland after the accident at the Chernobyl Nuclear Power Plant

    OpenAIRE

    Kapustinskaia O.A.

    2014-01-01

    The aim of the research - analysis of the structure and dynamics of the morbidity among eva¬cuated population, the peculiarities of pathogenesis of the most widespread forms of circulatory system (CS) pathology in the remote period after the accident at the Chernobyl Nuclear Power Plant. Materials and methods. Three groups of persons evacuated from Chernobyl zone of alienation were researched: persons aged 10-17 (6517 persons), 18-39 (496 persons), 40-60 (458 persons). The data on the individ...

  13. The peculiarities of formation of circulatory system pathology of evacuated adult population exposed to ionizing radiation on thyroid gland after the accident at the Chernobyl Nuclear Power Plant.

    OpenAIRE

    Kapustinskaia O.A.

    2014-01-01

    The aim of the research - analysis of the structure and dynamics of the morbidity among eva¬cuated population, the peculiarities of pathogenesis of the most widespread forms of circulatory system (CS) pathology in the remote period after the accident at the Chernobyl Nuclear Power Plant. Materials and methods. Three groups of persons evacuated from Chernobyl zone of alienation were researched: persons aged 10-17 (6517 persons), 18-39 (496 persons), 40-60 (458 persons). The data on the individ...

  14. Association of sulfur dioxide exposure with circulatory system deaths in a medium-sized city in Brazil

    Directory of Open Access Journals (Sweden)

    C.T. Amancio

    2012-11-01

    Full Text Available There is a demonstrable association between exposure to air pollutants and deaths due to cardiovascular diseases. The objective of this study was to estimate the effects of exposure to sulfur dioxide on mortality due to circulatory diseases in individuals 50 years of age or older residing in São José dos Campos, SP. This was a time-series ecological study for the years 2003 to 2007 using information on deaths due to circulatory disease obtained from Datasus reports. Data on daily levels of pollutants, particulate matter, sulfur dioxide (SO2, ozone, temperature, and humidity were obtained from the São Paulo State Environmental Agency. Moving average models for 2 to 7 days were calculated by Poisson regression using the R software. Exposure to SO2 was analyzed using a unipollutant, bipollutant or multipollutant model adjusted for mean temperature and humidity. The relative risks with 95%CI were obtained and the percent decrease in risk was calculated. There were 1928 deaths with a daily mean (± SD of 1.05 ± 1.03 (range: 0-6. Exposure to SO2 was significantly associated with mortality due to circulatory disease: RR = 1.04 (95%CI = 1.01 to 1.06 in the 7-day moving average, after adjusting for ozone. There was an 8.5% decrease in risk in the multipollutant model, proportional to a decrease of SO2 concentrations. The results of this study suggest that residents of medium-sized Brazilian cities with characteristics similar to those of São José dos Campos probably have health problems due to exposure to air pollutants.

  15. Association of sulfur dioxide exposure with circulatory system deaths in a medium-sized city in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Amancio, C.T. [Departamento de Medicina, Universidade de Taubaté, Taubaté, SP (Brazil); Nascimento, L.F.C. [Departamento de Medicina, Universidade de Taubaté, Taubaté, SP (Brazil); Programa de Pós-Graduação em Ciências Ambientais, Universidade de Taubaté, Taubaté, SP (Brazil)

    2012-08-17

    There is a demonstrable association between exposure to air pollutants and deaths due to cardiovascular diseases. The objective of this study was to estimate the effects of exposure to sulfur dioxide on mortality due to circulatory diseases in individuals 50 years of age or older residing in São José dos Campos, SP. This was a time-series ecological study for the years 2003 to 2007 using information on deaths due to circulatory disease obtained from Datasus reports. Data on daily levels of pollutants, particulate matter, sulfur dioxide (SO{sub 2}), ozone, temperature, and humidity were obtained from the São Paulo State Environmental Agency. Moving average models for 2 to 7 days were calculated by Poisson regression using the R software. Exposure to SO{sub 2} was analyzed using a unipollutant, bipollutant or multipollutant model adjusted for mean temperature and humidity. The relative risks with 95%CI were obtained and the percent decrease in risk was calculated. There were 1928 deaths with a daily mean (± SD) of 1.05 ± 1.03 (range: 0-6). Exposure to SO{sub 2} was significantly associated with mortality due to circulatory disease: RR = 1.04 (95%CI = 1.01 to 1.06) in the 7-day moving average, after adjusting for ozone. There was an 8.5% decrease in risk in the multipollutant model, proportional to a decrease of SO{sub 2} concentrations. The results of this study suggest that residents of medium-sized Brazilian cities with characteristics similar to those of São José dos Campos probably have health problems due to exposure to air pollutants.

  16. Association of sulfur dioxide exposure with circulatory system deaths in a medium-sized city in Brazil

    International Nuclear Information System (INIS)

    There is a demonstrable association between exposure to air pollutants and deaths due to cardiovascular diseases. The objective of this study was to estimate the effects of exposure to sulfur dioxide on mortality due to circulatory diseases in individuals 50 years of age or older residing in São José dos Campos, SP. This was a time-series ecological study for the years 2003 to 2007 using information on deaths due to circulatory disease obtained from Datasus reports. Data on daily levels of pollutants, particulate matter, sulfur dioxide (SO2), ozone, temperature, and humidity were obtained from the São Paulo State Environmental Agency. Moving average models for 2 to 7 days were calculated by Poisson regression using the R software. Exposure to SO2 was analyzed using a unipollutant, bipollutant or multipollutant model adjusted for mean temperature and humidity. The relative risks with 95%CI were obtained and the percent decrease in risk was calculated. There were 1928 deaths with a daily mean (± SD) of 1.05 ± 1.03 (range: 0-6). Exposure to SO2 was significantly associated with mortality due to circulatory disease: RR = 1.04 (95%CI = 1.01 to 1.06) in the 7-day moving average, after adjusting for ozone. There was an 8.5% decrease in risk in the multipollutant model, proportional to a decrease of SO2 concentrations. The results of this study suggest that residents of medium-sized Brazilian cities with characteristics similar to those of São José dos Campos probably have health problems due to exposure to air pollutants

  17. Patient support systems

    International Nuclear Information System (INIS)

    A patient support system for use in computerized tomography (CT) is described. The system is particularly useful for CT scanning of the brain and also of the abdominal area. The support system consists of two moveable tables which may be translated into position for X-ray scanning of the patient's body and which may be translated incrementally and automatically to obtain scans at adjacent locations. For use with brain scans, the second table is replaced by a detachable restraint assembly which is described in detail. The support system is so designed that only a small volume of low density material will intercept the X-ray beam. (UK)

  18. Development of a Deprivation Index and its relation to premature mortality due to diseases of the circulatory system in Hungary, 1998-2004.

    Science.gov (United States)

    Juhász, Attila; Nagy, Csilla; Páldy, Anna; Beale, Linda

    2010-05-01

    An association between health and socio-economic status is well known. Based on international and national studies, the aims of this study were to develop a multi-dimensional index at the municipality level, to provide information about socio-economic deprivation in Hungary and to investigate the association between socio-economic status and the spatial distribution of premature mortality due to diseases of the circulatory system. Seven municipality level socio-economic indicators were used from the National Information System of Spatial Development (income, low qualification, unemployment, one-parent families, large families, density of housing and car ownership). After normalisation and standardisation, indicator weights were evaluated using factor analysis. A risk analysis study was conducted using the Rapid Inquiry Facility software to evaluate the association between deprivation and the spatial distribution of premature mortality due to diseases of the circulatory system for the years 1998-2004. Areas of significantly high deprivation were identified in the northeastern, eastern and southwestern parts of Hungary. A statistically significant association was found between premature cardiovascular mortality and deprivation status in both genders. The Deprivation Index is the first composite index at the municipality level in Hungary and includes key factors that affect socio-economic status. The identified association highlighted the fact that inequalities in socio-economic status may reflect the spatial distribution of health status in a population. The results can be used to inform prevention strategies and help plan local health promotion programs aimed at reducing health inequalities. PMID:20199838

  19. The integrated decision support system

    International Nuclear Information System (INIS)

    This paper has introduced development history, present situation, popular decision support technology of decision support system, and discussed the integrated decision support system form with technical foundation. (authors)

  20. Group Support Systems (GSS)

    Science.gov (United States)

    Hamel, Gary P.; Wijesinghe, R.

    1996-01-01

    Groupware is a term describing an emerging computer software technology enhancing the ability of people to work together as a group, (a software driven 'group support system'). This project originated at the beginning of 1992 and reports were issued describing the activity through May 1995. These reports stressed the need for process as well as technology. That is, while the technology represented a computer assisted method for groups to work together, the Group Support System (GSS) technology als required an understanding of the facilitation process electronic meetings demand. Even people trained in traditional facilitation techniques did not necessarily aimlessly adopt groupware techniques. The latest phase of this activity attempted to (1) improve the facilitation process by developing training support for a portable groupware computer system, and (2) to explore settings and uses for the portable groupware system using different software, such as Lotus Notes.

  1. SAS Attitude Support System

    Science.gov (United States)

    Snyder, J. L.; Meyers, G. F.

    1972-01-01

    A unique ground control system was designed and implemented to support and meet the stringent mission requirements of the SAS-1. The important features of the system are described with emphasis on the software used to control the orientation of the spacecraft. A summary of the system's operation during the SAS-1 mission is given along with a discussion of the performance of the software subsystems relative to the mission requirements.

  2. Children's Beliefs about the Human Circulatory System: An Aid for Teachers Regarding the Role Intuitive Beliefs Play in the Development of Formal Concepts in 7-14-Year Olds. Report No. 82:16.

    Science.gov (United States)

    Catherall, Robin W.

    This exploratory study was aimed at uncovering children's beliefs and ideas about the human circulatory system. Thirty-two subjects, aged 7 to 14 years, were interviewed using a modification of Piaget's clinical method. The data were analyzed by developing a conceptual inventory of beliefs for each of five research questions. It was found that the…

  3. Mechanical circulatory support in treatment of children with refractory heart failure%辅助循环在婴幼儿难治性心力衰竭治疗中的应用

    Institute of Scientific and Technical Information of China (English)

    史珍英; 周燕萍; 徐卓明; 蔡及明; 朱丽敏; 李志浩; 傅惟定

    2011-01-01

    Objective To summarize the intensive care experience of extracorporeal membrane oxygenation (ECMO) and left ventricular assist device ( LYAD) in children with refractory heart failure. Methods Thirteen children having undergone operation for complicated congenital heart disease and I child with fulminant myocarditis received mechanical circulatory support due to refractory heart failure. There were 8 children in ECMO group and 6 children in LVAD group. The mean arterial pressure, central venous pressure, pressure of right atrium, pressure of left atrium, serum lactate concentration and oxygen saturation of mixed venous blood were monitored during mechanical circulatory support. The dosage of inotropic medicine was adjusted, the activated coagulation time was maintained between 150 s and 180 s, hematocrit between 30% and 35%, and platelet count >80 000/mm3. The mechanical circulatory support was weaned off when blood pressure was stable, pulse pressure was no lower than 20 mmHg, and left ventricular ejection fraction reached 50%. Results The mean time of mechanical circulatory support was (147 ± 152) h in ECMO group and LVAD group. During the mechanical circulatory support, the blood pressure increased from (48. 1 ±5.2) mmHg to (60.2 ±7. 8) mmHg (P <0. 05), while the serum lactate concentration decreased from (5. 1 ±0. 8) tnmol/L to (3.6 ±0.5) mraol/L (P <0.05). The survival rate of weaning off was 57. 1% (8/14), and the survival rate of hospital discharge was 42. 9% (6/14). The major complication was severe bleeding in thoracic and abdominal cavity (63.7%). Four children had indifferent mind (23.6%), and 8 had multiple organ dysfunction (57.1 %). During the follow up of 4 to 26 months, the left ventricular ejection fraction was no less than 50%, the cardiac function was class II, the growth of children was significantly improved, and mild to moderate neural sequela was found in 2 children- Conclusion Mechanical circulatory support plays an effective role in

  4. Hierarchical study of Guyton Circulatory Model

    OpenAIRE

    Assar, Rodrigo; Soueidan, Hayssam; Sherman, David James

    2009-01-01

    This article presents an initial study of the Guyton Circulatory Model using BioRica. This model consists of 18 connected modules, each of which caracterise a separate physiological subsystem. We have focused the present analysis in the Renin- Angiotensin-Aldosterone System (RAAS). The use of BioRica allowed us to build an hierarchical model for this system by means of directly mapping modules to BioRica nodes. The results of each node were validated by comparison with published results.

  5. Role and applications of circulatory models in cardiovascular pathophysiology.

    OpenAIRE

    Ferrari, Gianfranco; Kozarski, Maciej; Lazzari, Claudio,; Gorczynska, Krystyna; Palko, Jakub K.; K Zielinski; Di Molfetta, Arianna; Darowski, Marek

    2009-01-01

    Circulatory models are relevant for research, education and prosthetic devices/components testing. Independently of its structure that can be numerical, physical or hybrid, the models can be used in different areas of cardiovascular pathophysiology. However, the models are often used to reproduce specific circulatory conditions instead of being used as "systemic" tools. That is to say, the models are used to evaluate the global effects of external disturbances such as pathologies, therapies, ...

  6. Circulatory Syndrome: An Evolution of the Metabolic Syndrome Concept!

    OpenAIRE

    Khoshdel, Ali Reza; Carney, Shane L; Gillies, Alastair

    2012-01-01

    The metabolic syndrome has been a useful, though controversial construct in clinical practice as well as a valuable model in order to understand the interactions of diverse cardiovascular risk factors. However the increasing importance of the circulatory system in particular the endothelium , in both connecting and controlling organ function has underlined the limitations of the metabolic syndrome definition. The proposed “Circulatory Syndrome” is an attempt to refine the metabolic syndrome c...

  7. Effect of prone sleeping on circulatory control in infants

    OpenAIRE

    Chong, A; N. Murphy; MATTHEWS, T

    2000-01-01

    BACKGROUND—The mechanism of death in sudden infant death syndrome (SIDS) remains unclear. Progressive bradycardia is the pre-eminent terminal event, suggesting that circulatory failure might be a crucial factor. Vasomotor tone regulates the circulatory system by controlling blood volume distribution while maintaining venous return and blood pressure.
AIM—To examine whether prone sleeping, the most consistently identified risk factor for SIDS, has a measurable influence on...

  8. The abdominal circulatory pump.

    Directory of Open Access Journals (Sweden)

    Andrea Aliverti

    Full Text Available Blood in the splanchnic vasculature can be transferred to the extremities. We quantified such blood shifts in normal subjects by measuring trunk volume by optoelectronic plethysmography, simultaneously with changes in body volume by whole body plethysmography during contractions of the diaphragm and abdominal muscles. Trunk volume changes with blood shifts, but body volume does not so that the blood volume shifted between trunk and extremities (Vbs is the difference between changes in trunk and body volume. This is so because both trunk and body volume change identically with breathing and gas expansion or compression. During tidal breathing Vbs was 50-75 ml with an ejection fraction of 4-6% and an output of 750-1500 ml/min. Step increases in abdominal pressure resulted in rapid emptying presumably from the liver with a time constant of 0.61+/-0.1SE sec. followed by slower flow from non-hepatic viscera. The filling time constant was 0.57+/-0.09SE sec. Splanchnic emptying shifted up to 650 ml blood. With emptying, the increased hepatic vein flow increases the blood pressure at its entry into the inferior vena cava (IVC and abolishes the pressure gradient producing flow between the femoral vein and the IVC inducing blood pooling in the legs. The findings are important for exercise because the larger the Vbs the greater the perfusion of locomotor muscles. During asystolic cardiac arrest we calculate that appropriate timing of abdominal compression could produce an output of 6 L/min. so that the abdominal circulatory pump might act as an auxiliary heart.

  9. The peculiarities of formation of circulatory system pathology of evacuated adult population exposed to ionizing radiation on thyroid gland after the accident at the Chernobyl Nuclear Power Plant

    Directory of Open Access Journals (Sweden)

    Kapustinskaia O.A.

    2014-11-01

    Full Text Available The aim of the research - analysis of the structure and dynamics of the morbidity among eva¬cuated population, the peculiarities of pathogenesis of the most widespread forms of circulatory system (CS pathology in the remote period after the accident at the Chernobyl Nuclear Power Plant. Materials and methods. Three groups of persons evacuated from Chernobyl zone of alienation were researched: persons aged 10-17 (6517 persons, 18-39 (496 persons, 40-60 (458 persons. The data on the individual radiation doses which affected thyroid gland were selected at the State Register of Ukraine on persons affected by the Chernobyl disaster. Morbidity rate was estimated per 103 man-year for 5-years periods of monitoring. The main results: Time from the moment of Chernobyl accident affected the formation of morbidity structure of evacuated population. It was fixed two peaks of morbidity incidence - initial and in 12 years. The most essential changes in CS morbidity of evacuated population were fixed 26 years later mainly in cere¬brovascular diseases. The coronary artery disease takes the first place in the morbidity structure. Significant dif¬ferences were detected at age-specific aspect. The evacuated adult population aged 18-39 years was the most vulnerable for the development of CS diseases. Adverse health effects confirmed the necessity of further research of CS morbidity with the differentiation of doses affected thyroid gland.

  10. Decision support systems

    DEFF Research Database (Denmark)

    Jørgensen, L.N.; Noe, E.; Langvad, A.M.;

    2007-01-01

    system Crop Protection Online is widely used by advisors and as a learning tool for students. Although the system has been validated in many field trials over the years and has shown reliable results, the number of end-users among farmers has been relatively low during the last 10 years (approximately...... 1000 farmers). A sociological investigation of farmers' decision-making styles in the area of crop protection has shown that arable farmers can be divided into three major groups: (a) system-orientated farmers, (b) experience-based farmers and (c) advisory-orientated farmers. The information required...

  11. Intelligence operator support system

    International Nuclear Information System (INIS)

    The paper describes a system which is capable of discerning an onset of abnormal situations arising in the course of the NPP operation and providing recommendations to the operator in his control actions. The system represents a set of interrelated algorithm with two models. One is intended for automatic diagnostics of the functioning of the on-board ''Topaz-2'' type SNPP. The other can be used as a part of the automatic control system of the technological processes in the NPP. The software is intended for the implementation in the IBM-PC/AT compatible computers. (author). 3 figs

  12. Design of decision support systems

    International Nuclear Information System (INIS)

    The paper is addressing the design of decision support systems to be used in the nuclear industry and the requirements placed on such systems. A general model of the decision-making situation is proposed for the structuring of the different functions provided by the decision support system. The relative merits of different functions of the support systems and their practical implementation are discussed. A proposal for the functions to be included in a decision support system is given as a result fo the discussion. The practical design of decision support system is discussed, and some general remarks on the management of design projects are given. The use of decision support systems and their integration in the every day routines are also discussed. Reference is given to experiments, where a large scale validation of decision support systems have been attempted. One of the findings from the validation experiments, is that it might be difficult or even impossible to prove the benefit of a proposed design of a decision support system in quantitative terms. Present design practices are bringing in the concern for the human as a part of the system comparatively late and in a rather unsystematic way. As a conclusion it is argued that more effort should be spent in building up an understanding of the dynamics of design projects. Such an understanding can be used to create better models for carrying out the design projects and to specify different design tools to be used. (author). 17 refs, 1 fig, 5 tabs

  13. System for technical innovation support

    International Nuclear Information System (INIS)

    This book lists field of support system, which includes tax, development work, basic research project, industrial technology, information and communications field, energy field, part and materials field, local industry, the small and medium business such as technical development field, and industry-university collaboration like summary of investment and financing support and guarantee, support of manpower such as brain pool and contact Korea, support of technique like development technology and strategy for patent, support on certification such as company and technical goods, purchase support.

  14. Web-based support systems

    CERN Document Server

    Yao, JingTao

    2010-01-01

    The emerging interdisciplinary study of Web-based support systems focuses on the theories, technologies and tools for the design and implementation of Web-based systems that support various human activities. This book presents the state-of-the-art in Web-based support systems (WSS). The research on WSS is multidisciplinary and focuses on supporting various human activities in different domains/fields based on computer science, information technology, and Web technology. The main goal is to take the opportunities of the Web, to meet the challenges of the Web, to extend the human physical limita

  15. Clinical Information Support System (CISS)

    Data.gov (United States)

    Department of Veterans Affairs — Clinical Information Support System (CISS) is a web-based portal application that provides a framework of services for the VA enterprise and supplies an integration...

  16. Snake constriction rapidly induces circulatory arrest in rats.

    Science.gov (United States)

    Boback, Scott M; McCann, Katelyn J; Wood, Kevin A; McNeal, Patrick M; Blankenship, Emmett L; Zwemer, Charles F

    2015-07-01

    As legless predators, snakes are unique in their ability to immobilize and kill their prey through the process of constriction, and yet how this pressure incapacitates and ultimately kills the prey remains unknown. In this study, we examined the cardiovascular function of anesthetized rats before, during and after being constricted by boas (Boa constrictor) to examine the effect of constriction on the prey's circulatory function. The results demonstrate that within 6 s of being constricted, peripheral arterial blood pressure (PBP) at the femoral artery dropped to 1/2 of baseline values while central venous pressure (CVP) increased 6-fold from baseline during the same time. Electrocardiographic recordings from the anesthetized rat's heart revealed profound bradycardia as heart rate (fH) dropped to nearly half of baseline within 60 s of being constricted, and QRS duration nearly doubled over the same time period. By the end of constriction (mean 6.5±1 min), rat PBP dropped 2.9-fold, fH dropped 3.9-fold, systemic perfusion pressure (SPP=PBP-CVP) dropped 5.7-fold, and 91% of rats (10 of 11) had evidence of cardiac electrical dysfunction. Blood drawn immediately after constriction revealed that, relative to baseline, rats were hyperkalemic (serum potassium levels nearly doubled) and acidotic (blood pH dropped from 7.4 to 7.0). These results are the first to document the physiological response of prey to constriction and support the hypothesis that snake constriction induces rapid prey death due to circulatory arrest. PMID:26202779

  17. User's instructions for the Guyton circulatory dynamics model using the Univac 1110 batch and demand processing (with graphic capabilities)

    Science.gov (United States)

    Archer, G. T.

    1974-01-01

    The model presents a systems analysis of a human circulatory regulation based almost entirely on experimental data and cumulative present knowledge of the many facets of the circulatory system. The model itself consists of eighteen different major systems that enter into circulatory control. These systems are grouped into sixteen distinct subprograms that are melded together to form the total model. The model develops circulatory and fluid regulation in a simultaneous manner. Thus, the effects of hormonal and autonomic control, electrolyte regulation, and excretory dynamics are all important and are all included in the model.

  18. [Remote radiation planning support system].

    Science.gov (United States)

    Atsumi, Kazushige; Nakamura, Katsumasa; Yoshidome, Satoshi; Shioyama, Yoshiyuki; Sasaki, Tomonari; Ohga, Saiji; Yoshitake, Tadamasa; Shinoto, Makoto; Asai, Kaori; Sakamoto, Katsumi; Hirakawa, Masakazu; Honda, Hiroshi

    2012-08-01

    We constructed a remote radiation planning support system between Kyushu University Hospital (KUH) in Fukuoka and Kyushu University Beppu Hospital (KBH) in Oita. Between two institutions, radiology information system for radiotherapy division (RT-RIS) and radiation planning system (RTPS) were connected by virtual private network (VPN). This system enables the radiation oncologists at KUH to perform radiotherapy planning for the patients at KBH. The detail of the remote radiation planning support system in our institutions is as follows: The radiation oncologist at KBH performs radiotherapy planning and the data of the patients are sent anonymously to the radiation oncologists at KUH. The radiation oncologists at KUH receive the patient's data, access to RTPS at KBH, verify or change the radiation planning at KBH: Radiation therapy is performed at KBH according to the confirmed plan by the radiation oncologists at KUH. Our remote radiation planning system is useful for providing radiation therapy with safety and accuracy. PMID:23157128

  19. Systems Support for Collaborative Learning

    OpenAIRE

    Allison, Collin; Ruddle, Alan; Michaelson, Rosa

    2002-01-01

    One of the distinguishing features of novel network based learning environments is their capability to support group work and collaboration. TAGS, the Tutor and Groups Support Scheme, is an inter-disciplinary, inter-institutional project, which brings together software systems builders, subject-specialists and educational content developers. Collaborative Learning is central to the pedagogical goals of TAGS, and this has lead to the concept of groups being used as a fundamental organising pri...

  20. ELECTRICAL SUPPORT SYSTEM DESCRIPTION DOCUMENT

    International Nuclear Information System (INIS)

    The purpose of this revision of the System Design Description (SDD) is to establish requirements that drive the design of the electrical support system and their bases to allow the design effort to proceed to License Application. This SDD is a living document that will be revised at strategic points as the design matures over time. This SDD identifies the requirements and describes the system design as they exist at this time, with emphasis on those attributes of the design provided to meet the requirements. This SDD has been developed to be an engineering tool for design control. Accordingly, the primary audience/users are design engineers. This type of SDD both ''leads'' and ''trails'' the design process. It leads the design process with regard to the flow down of upper tier requirements onto the system. Knowledge of these requirements is essential in performing the design process. The SDD trails the design with regard to the description of the system. The description provided in the SDD is a reflection of the results of the design process to date. Functional and operational requirements applicable to electrical support systems are obtained from the ''Project Functional and Operational Requirements'' (F andOR) (Siddoway 2003). Other requirements to support the design process have been taken from higher-level requirements documents such as the ''Project Design Criteria Document'' (PDC) (Doraswamy 2004), and fire hazards analyses. The above-mentioned low-level documents address ''Project Requirements Document'' (PRD) (Canon and Leitner 2003) requirements. This SDD contains several appendices that include supporting information. Appendix B lists key system charts, diagrams, drawings, and lists, and Appendix C includes a list of system procedures

  1. KESS: Knowledge Engineering Support System

    OpenAIRE

    Said, Mohamed Ben; Dougherty, Nini; Anderson, Curtis; Altman, Stanley J.; Bouhaddou, Omar; Warner, Homer R

    1987-01-01

    KESS (Knowledge Engineering Support System) is a relational information management system created at the University of Utah to document each step in the building of four expert knowledge bases. In weekly knowledge engineering sessions, groups of experts propose decision making criteria and examine information sources in the process of creating HELP knowledge frames. KESS utilizes many-to-many links with multiple files and central link files to track the different kinds of information generate...

  2. Integrated logistic support analysis system

    International Nuclear Information System (INIS)

    Integrating logic support into a system results in a large volume of information having to be managed which can only be achieved with the help of computer applications. Both past experience and growing needs in such tasks have led Emperesarios Agrupados to undertake an ambitious development project which is described in this paper. (author)

  3. The Life Support Database system

    Science.gov (United States)

    Likens, William C.

    1991-01-01

    The design and implementation of the database system are described with specific reference to data available from the Build-1 version and techniques for its utilization. The review of the initial documents for the Life Support Database is described in terms of title format and sequencing, and the users are defined as participants in NASA-sponsored life-support research. The software and hardware selections are based respectively on referential integrity and compatibility, and the implementation of the user interface is achieved by means of an applications-programming tool. The current Beta-Test implementation of the system includes several thousand acronyms and bibliographic references as well as chemical properties and exposure limits, equipment, construction materials, and mission data. In spite of modifications in the database the system is found to be effective and a potentially significant resource for the aerospace community.

  4. The course of circulatory and cerebral recovery after circulatory arrest: influence of pre-arrest, arrest and post-arrest factors.

    Science.gov (United States)

    Jørgensen, E O; Holm, S

    1999-11-01

    We evaluated the influence of pre-arrest, arrest and post-arrest factors on circulatory and neurological recovery for up to 1 year following circulatory arrest of cardio-pulmonary aetiology in 231 patients. Initially, all patients were unconscious and 106 had some cortical activity recorded in the immediate post-resuscitation EEG (Group I), while 125 had no such activity initially (Group II). The following variables were explored: age, sex, medical history, cause and location of arrest, initial cardiac dysrhythmia, duration of life support, metabolic acidosis, pulse-pressure product and heart pump function capacity early after resuscitation. Outcome measures were duration and quality of circulatory survival, cause of death, neurological recovery and ultimate outcome. First year survival was 33% in Group I and 16% in Group II. Severe heart failure and brain death occurred mainly in Group II. Circulatory recovery was negatively influenced by out-of-hospital arrest, metabolic acidosis and pulse-pressure products below 150. Neurological recovery was negatively influenced by initial dysrhythmias other than ventricular fibrillation, pulse-pressure products below 150, post-arrest heart failure and/or pulmonary complications. It seems that circulatory and cerebral outcomes are mainly determined by the global ischaemic insults sustained during the circulatory arrest period. PMID:10625157

  5. Operator Performance Support System (OPSS)

    Science.gov (United States)

    Conklin, Marlen Z.

    1993-01-01

    In the complex and fast reaction world of military operations, present technologies, combined with tactical situations, have flooded the operator with assorted information that he is expected to process instantly. As technologies progress, this flow of data and information have both guided and overwhelmed the operator. However, the technologies that have confounded many operators today can be used to assist him -- thus the Operator Performance Support Team. In this paper we propose an operator support station that incorporates the elements of Video and Image Databases, productivity Software, Interactive Computer Based Training, Hypertext/Hypermedia Databases, Expert Programs, and Human Factors Engineering. The Operator Performance Support System will provide the operator with an integrating on-line information/knowledge system that will guide expert or novice to correct systems operations. Although the OPSS is being developed for the Navy, the performance of the workforce in today's competitive industry is of major concern. The concepts presented in this paper which address ASW systems software design issues are also directly applicable to industry. the OPSS will propose practical applications in how to more closely align the relationships between technical knowledge and equipment operator performance.

  6. Spill operation system decision support system

    International Nuclear Information System (INIS)

    The MSRC Spill Operation System (SOS) is a tool for the support of decision-making at the time of a catastrophic oil spill. SOS provides MSRC decision-makers with access to information about the source of the spill, the spill environment, and the availability of spill response resources. This system is designed to meet the information needs of a Response Supervisor, an Environmental Advisor, Logistics/Maintenance Supervisor, Operations Supervisor, and the MSRC Regional General Manager. The SOS project Objectives are: (1) integrate currently available data, systems, and technologies; (2) develop an application that effectively supports mobilized operations and can be adapted to support normal operations; (3) ensure that the development of computer applications is driven by user needs and not by technology; and (4) coordinate with government and other industry organizations to avoid duplication of effort. Design Objectives for SOS are: (1) centralize management information storage while decentralizing decision making capabilities; (2) boost User confidence by providing a system that is easy to learn, easy to use, and is open-quotes Sailor Proofclose quotes; and (3) use visualization technology in providing spill related information. This approach includes the use of Geographic Information System (GIS) technology for maps and geographically associated resource; and support MSRC's concept of operation which includes - a swift notification of response personnel; fast mobilization of response resources; and accurate tracking of resources during a spill. MSRC is organized into five responsibility regions

  7. Information Systems as Support to Corporate Management

    OpenAIRE

    Florida Veljanoska; Majlinda Axhiu

    2013-01-01

    The idea of this paper is to introduce the great support of information systems to the management activities of a corporation. Information system as a combination of information technology and peoples actions that support operations, management and decision making, involves four major types of systems: Transaction Management System, Management Information System, Decision-Support System and Executive Support System, and with that it is able to entail and support all business activities. In tr...

  8. Advanced support systems development and supporting technologies for Controlled Ecological Life Support Systems (CELSS)

    Science.gov (United States)

    Simon, William E.; Li, Ku-Yen; Yaws, Carl L.; Mei, Harry T.; Nguyen, Vinh D.; Chu, Hsing-Wei

    1994-01-01

    A methyl acetate reactor was developed to perform a subscale kinetic investigation in the design and optimization of a full-scale metabolic simulator for long term testing of life support systems. Other tasks in support of the closed ecological life support system test program included: (1) heating, ventilation and air conditioning analysis of a variable pressure growth chamber, (2) experimental design for statistical analysis of plant crops, (3) resource recovery for closed life support systems, and (4) development of data acquisition software for automating an environmental growth chamber.

  9. Separation of craniopagus Siamese twins using cardiopulmonary bypass and hypothermic circulatory arrest.

    Science.gov (United States)

    Cameron, D E; Reitz, B A; Carson, B S; Long, D M; Dufresne, C R; Vander Kolk, C A; Maxwell, L G; Tilghman, D M; Nichols, D G; Wetzel, R C

    1989-11-01

    Occipitally joined craniopagus Siamese twins were separated with the use of cardiopulmonary bypass and hypothermic circulatory arrest. The 7-month-old infants shared a large sagittal venous sinus that precluded conventional neurosurgical approach because of risk of exsanguination and air embolism. After craniotomy and preliminary exposure of the sinus, each twin underwent sternotomy and total cardiopulmonary bypass with deep hypothermia. Hypothermic circulatory arrest allowed safe division and subsequent reconstruction of the sinus remnants. Several unusual problems were encountered, including transfusion of a large blood volume from one extracorporeal circuit to the other through the common venous sinus, deleterious warming of the exposed brain during circulatory arrest, and thrombosis of both pump oxygenators. Both infants survived, although recovery was complicated in each by neurologic injury, cranial wound infection, and hydrocephalus. This case demonstrates the valuable supportive role of cardiopulmonary bypass and hypothermic circulatory arrest in the management of complex surgical problems of otherwise inoperable patients. PMID:2682024

  10. Cell-Mediated Delivery of Nanoparticles: Taking Advantage of Circulatory Cells to Target Nanoparticles

    OpenAIRE

    Anselmo, Aaron C.; Mitragotri, Samir

    2014-01-01

    Cellular hitchhiking leverages the use of circulatory cells to enhance the biological outcome of nanoparticle drug delivery systems, which often suffer from poor circulation time and limited targeting. Cellular hitchhiking utilizes the natural abilities of circulatory cells to: (i) navigate the vasculature while avoiding immune system clearance, (ii) remain relatively inert until needed and (iii) perform specific functions, including nutrient delivery to tissues, clearance of pathogens, and i...

  11. Secondary School Students’ Misconceptions About the “Transportation and Circulatory Systems” Unit

    Directory of Open Access Journals (Sweden)

    Selâmi Yeşilyurt

    2012-01-01

    Full Text Available The purpose of this study was to determine secondary school students’ misconceptions about the “Transportation and Circulatory Systems” unit in biology course. The study was conducted with totally 78 students who were 11th graders being taught in three secondary schools in Erzurum. In the study, a valid and reliable “Misconception Diagnosis Test” was administered to students to determine their misconceptions about the “Transportation and Circulatory Systems” unit. Data were analyzed by means of SPSS 12.0. Findings showed that students had various misconceptions about the “Transportation and Circulatory Systems” unit such as osmotic pressure and water absorption, transpiration and cohesion force, open and closed circulation, structure of the heart and heart bumping, blood vessels, blood and blood cells, blood pressure, relation of the circulatory system to other systems, lymphatic system, defense and immune. At the end of the study, recommendations were made to remove students’ misconceptions.

  12. System Support for Forensic Inference

    Science.gov (United States)

    Gehani, Ashish; Kirchner, Florent; Shankar, Natarajan

    Digital evidence is playing an increasingly important role in prosecuting crimes. The reasons are manifold: financially lucrative targets are now connected online, systems are so complex that vulnerabilities abound and strong digital identities are being adopted, making audit trails more useful. If the discoveries of forensic analysts are to hold up to scrutiny in court, they must meet the standard for scientific evidence. Software systems are currently developed without consideration of this fact. This paper argues for the development of a formal framework for constructing “digital artifacts” that can serve as proxies for physical evidence; a system so imbued would facilitate sound digital forensic inference. A case study involving a filesystem augmentation that provides transparent support for forensic inference is described.

  13. [Organ donation after circulatory death].

    Science.gov (United States)

    de Jonge, J; Kalisvaart, M; van der Hoeven, M; Epker, J; de Haan, J; IJzermans, J N M; Grüne, F

    2016-02-01

    Approximately 17 million inhabitants live in the Netherlands. The number of potential organ donors in 1999 was the lowest in Europe with only 10 donors per million inhabitants. Medical associations, public health services, health insurance companies and the government had to find common solutions in order to improve organ allocation, logistics of donations and to increase the number of transplantations. After a prolonged debate on medical ethical issues of organ transplantation, all participants were able to agree on socio-medico-legal regulations for organ donation and transplantation. In addition to improving the procedure for organ donation after brain death (DBD) the most important step was the introduction of organ donation after circulatory death (DCD). Measures such as the introduction of a national organ donor database, improved information to the public, further education on intensive care units (ICU), guidelines for end of life care on the ICU, establishment of transplantation coordinators on site, introduction of autonomous explantation teams and strict procedures on the course of organ donations, answered many practical issues about logistics and responsibilities for DBD and DCD. In 2014 the number of postmortem organ donations rose to 16.4 per million inhabitants. Meanwhile, up to 60 % of organ donations in the Netherlands originate from a DCD procedure compared to approximately 10 % in the USA. This overview article discusses the developments and processes of deceased donation in the Netherlands after 15 years of experience with DCD. PMID:26810404

  14. Parallel left ventricular assistance tests on the hybrid circulatory model.

    OpenAIRE

    Kozarski, Maciej; Ferrari, Gianfranco; Zielinski, Krzysztof; Gorczynska, Krystyna; Palko, Krzysztof Jakub; Darowski, Marek

    2009-01-01

    Objectives: Evaluation of new control and measurement methods worked out for heart assist devices and artificial hearts need new laboratory tools making experiments more accurate, repeatable, easier and less time consuming. The proper answer to this demand seems to be a hybrid hydro-numerical model HHNM of the circulatory system. Its performance illustrates the exemplary laboratory application when the physical left ventricle assist device is connected in parallel to the numerical left ventri...

  15. Trends in death from circulatory diseases in Brazil between 1979 and 1996

    OpenAIRE

    2001-01-01

    OBJECTIVE: To analyze the trends in mortality due to circulatory diseases in men and women aged > or = 30 years in Brazil from 1979 to 1996. METHODS: We analyzed population count data obtained from the IBGE Foundation and mortality data obtained from the System of Information on Mortality of the DATASUS of the Ministry of Health. RESULTS: Circulatory diseases, ischemic heart disease, and cerebrovascular disease were the major causes of death in men and women in Brazil. The standardized age c...

  16. Cortical brain microdialysis and temperature monitoring during hypothermic circulatory arrest in humans

    OpenAIRE

    Mendelowitsch, A; Mergner, G; Shuaib, A.; Sekhar, L

    1998-01-01

    OBJECTIVES—Critical vascular surgery of the brain or the heart occasionally requires total cessation of the circulatory system. Profound hypothermia is used to protect the brain from ischaemic injury. This study explores the use of microdialysis to measure metabolic indices of ischaemia: glutamate, lactate, and pH, and cerebral temperature during profound hypothermia and circulatory arrest.
METHODS—Effluent from a microdialysis catheter placed in the cerebral cortex of three...

  17. Electrocardiograph and photoplethysmograph superimposition as an investigative tool for circulatory function

    OpenAIRE

    Maguire, Michael; Markham, Charles; Ward, Tomas

    2001-01-01

    This paper set out to examine the usefulness of the electrocardiograph (ECG) and photoplethysmograph (PPG) superimposition as an investigative tool for circulatory function. Further, a system was constructed and an experimental protocol established to examine this proposition. The three main components of circulatory function are pulse rate, arterial compliance and blood pressure. These components are each interrelated, and these relationships are the subject of much research. It was decided,...

  18. Decision support system to select cover systems

    International Nuclear Information System (INIS)

    The objective of this technology is to provide risk managers with a defensible, objective way to select capping alternatives for remediating radioactive and mixed waste landfills. The process of selecting containment cover technologies for mixed waste landfills requires consideration of many complex and interrelated technical, regulatory, and economic issues. A Decision Support System (DSS) is needed to integrate the knowledge of experts from scientific, engineering, and management disciplines to help in selecting the best capping practice for the site

  19. Current discussions of DDREF, cataracts, circulatory diseases and dose limits

    International Nuclear Information System (INIS)

    Although more than a century of radiation research has provided a lot of insight into radiation risk, there are still fields that need clarification. This is particularly true for the low dose range, meaning doses up to ∼100 mSv. One can detect biological effects in that dose range, but it is unclear whether these biological effects like mutations or chromosomal aberrations translate into health effects like cancer, cataracts or circulatory diseases. Thus, for radiation protection purposes, assumptions have to made that must be reappraised on the basis of new findings from time to time. Affected by new insights are currently the DDREF (dose and dose-rate effectiveness factor), cataracts and circulatory diseases. If the new findings are very convincing, dose limits have to be changed at short notice. If there are only weak indications, stability of the radiation protection system is more important than changing limits all the time. (authors)

  20. Bioregenerative life-support systems

    Science.gov (United States)

    Mitchell, C. A.

    1994-01-01

    Long-duration future habitation of space involving great distances from Earth and/or large crew sizes (eg, lunar outpost, Mars base) will require a controlled ecological life-support system (CELSS) to simultaneously revitalize atmosphere (liberate oxygen and fix carbon dioxide), purify water (via transpiration), and generate human food (for a vegetarian diet). Photosynthetic higher plants and algae will provide the essential functions of biomass productivity in a CELSS, and a combination of physicochemical and bioregenerative processes will be used to regenerate renewable resources from waste materials. Crop selection criteria for a CELSS include nutritional use characteristics as well as horticultural characteristics. Cereals, legumes, and oilseed crops are used to provide the major macronutrients for the CELSS diet. A National Aeronautics and Space Administration (NASA) Specialized Center of Research and Training (NSCORT) was established at Purdue University to establish proof of the concept of the sustainability of a CELSS. The Biosphere 2 project in Arizona is providing a model for predicted and unpredicted situations that arise as a result of closure in a complex natural ecosystem.

  1. Energy absorbing supports - an alternative piping support system

    International Nuclear Information System (INIS)

    An extensive development effort has resulted in the successful application of energy absorbers as alternative supports. Several installations of energy absorbers demonstrating the feasibility of this support concept have been successfully completed. Designed in accordance with the ASME Code Case N-420, these ductile supports undergo limited and controlled yielding under dynamic conditions, thereby dissipating energy. The design methodology determines the specific damping ratios applicable for a given piping system on the basis of the energy absorbers used. Thus, using energy absorbers permits predictable damping to be engineered into the system desing. They can be used in operating plants to replace existing snubbers. In plants under construction, they can be used in place of both snubbers and rigid supports. In both applications, fewer energy absorbers are required as compared to snubbers and rigid supports. (orig.)

  2. Energy absorbing supports - An alternative piping support system

    International Nuclear Information System (INIS)

    An extensive development effort has resulted in the successful application of energy absorbers as alternative supports. Several installations of energy absorbers demonstrating the feasibility of this support concept have been successfully completed. Designed in accordance with the ASME Code Case N-420, these ductile supports undergo limited and controlled yielding under dynamic conditions, thereby dissipating energy. The design methodology determines the specific damping ratios applicable for a given piping system on the basis of the energy absorbers used. Thus, using energy absorbers permits predictable damping to be engineered into the system design. They can be used in operating plants to replace existing snubbers. In plants under construction, they can be used in place of both snubbers and rigid supports. In both applications, fewer energy absorbers are required as compared to snubbers and rigid supports

  3. A Contemplation of Training Decision Support System

    OpenAIRE

    P.Kalpana,; Dr . T . Bhuvaneswari

    2011-01-01

    This research paper presents a role of decision support system in Human Resource Training Systems. A deep understanding of the knowledge hidden in Human Resource (HR) data is vital to a firm's competitive position and organizational decision making. The HR data is usually treated to answer queries. Training Decision Support System (TDSS) data primarily concerns Transactional process and Executive support system is used to retrieve data from the system, recording it for future purposes. The pa...

  4. A SYSTEM TO SUPPORT TEAM CREATION

    OpenAIRE

    XINMIAO LI; PENGZHU ZHANG; LUNING XIE; RUYI GE

    2007-01-01

    Creation has been regarded as the most valuable advantage of corporations since the 1990s. However, team creation generally lacks effective support methods and support tools at present. It is important to research how to support team creation. In this paper, we design a system to support team creation, the main functions of which are team information record, knowledge visualization, and information relationship recognition.

  5. Decision time for clinical decision support systems

    OpenAIRE

    O'Sullivan, D.; Fraccaro, P.; Carson, E; Weller, P

    2014-01-01

    Clinical decision support systems are interactive software systems designed to assist clinicians with decision making tasks, such as determining a diagnosis or recommending a treatment for a patient. Clinical decision support systems are a widely researched topic in the Computer Science community but their inner workings are less well understood by and known to clinicians. In this article we provide a brief explanation of clinical decision support systems and provide some examples of real wor...

  6. Circulatory abnormalities in cirrhosis with focus on neurohumoral aspects

    DEFF Research Database (Denmark)

    Møller, Søren; Henriksen, Jens Henrik

    1997-01-01

    resistance are decreased. A peripheral arterial vasodilatation may be of pathogenic importance to the low systemic vascular resistance as it directly correlates to the degree of central hypovolemia. It may therefore be an important element in the development of the low arterial blood pressure and......-angiotensin-aldosterone system, and elevated circulating vasopressin, endothelin-1 may also be implicated in the hemodynamic counter-regulation in cirrhosis. Recent research has focused on the assertion that the hemodynamic and neurohumoral abnormalities in cirrhosis are part of a general circulatory dysfunction influencing the...

  7. Support Systems for Treatment Integrity

    Science.gov (United States)

    Goense, Pauline Brigitta; Boendermaker, Leonieke; van Yperen, Tom

    2016-01-01

    Objective: This systematic review evaluates the content of effective support provided to practitioners of evidence-based interventions in order to establish and maintain treatment integrity. Method: Four articles covering six outcome studies are included in this review, these studies (1) adequately operationalized treatment integrity procedures…

  8. Developing Information Systems for Competitive Intelligence Support.

    Science.gov (United States)

    Hohhof, Bonnie

    1994-01-01

    Discusses issues connected with developing information systems for competitive intelligence support; defines the elements of an effective competitive information system; and summarizes issues affecting system design and implementation. Highlights include intelligence information; information needs; information sources; decision making; and…

  9. Financial Decision Making Support System

    OpenAIRE

    Lobanova, E. N.; Zmitrovich, A. I.; Voshevoz, A. A.; Krivko-Krasko, A. V.

    2010-01-01

    In this article we consider concepts and components of the Financial Decision Making System that is being developed in the Institute of Business and Management Technology, BSU. Such system can be successfully used either for training experts in financial analytics and financial management or for financial managers and financial directors in an enterprise for the effective financial decision making.

  10. A customized head and neck support system

    International Nuclear Information System (INIS)

    Purpose: To describe a customized head and neck immobilization system for patients receiving radiotherapy including a head support that conforms to the posterior contour of the head and neck. Methods: The system includes a customized headrest to support the posterior head and neck. This is fixed to a thermoplastic face mask that molds to the anterior head/face contours. The shape of these customized head and neck supports were compared to 'standard' supports. Results: This system is comfortable for the patients and appears to be effective in reproducing the setup of the treatment. Conclusions: The variability in the size and shape of the customized posterior supports exceeded that of 'standard' headrests. It is our clinical impression that the customized supports improve reproducibility and are now a standard part of our immobilization system. The quantitative analysis of the customized headrests and some commonly used 'standard' headrests suggests that the customized supports are better able to address variabilities in patient shape

  11. Anastomose cavo-pulmonar associada ao suporte circulatório esquerdo comparada à assistência biventricular na falência cardíaca aguda Cavo-pulmonary anastomosis associated with left ventricular in comparison with biventricular circulatory support in acute heart failure

    Directory of Open Access Journals (Sweden)

    Luis Alberto Saraiva Santos

    2012-12-01

    Full Text Available OBJETIVO: Este estudo avaliou o desempenho hemodinâmico e as alterações miocárdicas decorrentes do emprego de dispositivos de assistência ventricular esquerda (DAVE, associado ou não à descompressão do ventrículo direito por meio de derivação cavo-pulmonar, sendo esses achados comparados ao emprego de assistência circulatória biventricular. MÉTODOS: Vinte e um suínos foram submetidos à indução de insuficiência cardíaca através de fibrilação ventricular, sendo a atividade circulatória mantida por DAVE durante 180 minutos. No grupo controle, foi apenas implantado o DAVE. No grupo derivação, além do DAVE foi realizada cirurgia de derivação cavo-pulmonar. No grupo biventricular, foi instituída assistência biventricular. Foram monitoradas as pressões intracavitárias por 3 horas de assistência e amostras do endocárdio dos dois ventrículos foram coletadas e analisadas à microscopia óptica e eletrônica. RESULTADOS: O lactato sérico foi significativamente menor no grupo biventricular (P=0,014. A diferença observada entre o fluxo do DAVE nos grupos derivação e controle (+55±14 ml/kg/min, P=0,072 não foi significativa, enquanto que o fluxo no grupo biventricular foi significativamente maior (+93±17 ml/kg/min, P=0,012 e se manteve estável durante o experimento. A pressão arterial média (PAM se manteve constante apenas no grupo biventricular (POBJECTIVE: Right ventricular (RV failure during left ventricular assist device (LVAD support can result in severe hemodynamic compromise with high mortality. This study investigated the acute effects of cavo-pulmonary anastomosis on LVAD performance and RV myocardial compromise in comparison with biventricular circulatory support, in a model of biventricular failure. METHODS: LVAD support was performed by centrifugal pump in 21 pigs with severe biventricular failure obtained by FV induction. Animals were randomized to be submitted to cavo-pulmonary anastomosis, to

  12. On the Instability of Equilibrium of Nonholonomic Systems With Dissipation and Circulatory Forces%非完整系统有耗散和循环力时的平衡不稳定性

    Institute of Scientific and Technical Information of China (English)

    M·韦仕科尉克; V·科尉克; A·奥布拉德尉克

    2011-01-01

    The equilibrium instability problem of the scleronomic nonholonomic systems acted upon by dissipative, conservative, circulatory forces was discussed. The applied methodology was based on the existence of solutions of differential equations of motion which asymptotically tend to the equilibrium state of the system, as t →- ∞. It was assumed that the kinetic energy,the Rayleigh dissipation function, the positional forces in the neighborhood of the equilibrium position are infinitely differentiable functions. The results obtained, which partially generalize results from [ V V Kozlov. On the asymptotic motions of systems with dissipation. Prikl Math Mekh, 1994, 58 (4): 31-36. (in Russian); D R Merkin. Introduction to the Theory of the Stability of Motion. 1987, Moscow: Nauka. (in Russian); W Thomson, P Tait. Treatise on Natural Philosophy. Part Ⅰ. Cambridge University Press, 1879], are illustrated by an example.%讨论定常非完整系统在耗散、保守、循环力作用下的不稳定平衡问题.应用方法是基于运动微分方程解的存在性,当t→-∞时,系统渐近地趋于平衡状态.假定在平衡位置附近,动能、Reyleigh耗散函数、位置力都是无限可微函数.结果将通过一个实例说明.部分结果参见Kozlov V V.On the asymptotic motions of systems with dissipation.Prikl Math Mekh,1994,58(4):31-36.(in Russian):Merkin D R.Introduction to the Theory of the Stability of Motion.Moscow:Nauka,1987.(in Russian);Thomson W,Tait P.Treatise on Natural Philosophy,Part Ⅰ[M].Cambridge:Cambridge University Press,1879.

  13. PPL Travel & Mission Support System

    Data.gov (United States)

    US Agency for International Development — PTRAMS is a travel data collection system for PPL that collects information on both the basic details of an employee's trips (destination, length, purpose, etc.)...

  14. DCHA Travel & Mission Support System

    Data.gov (United States)

    US Agency for International Development — DTRAMS is a travel data collection system for DCHA that collects information on both the basic details of an employee's trips (destination, length, purpose, etc.)...

  15. GH Travel & Mission Support System

    Data.gov (United States)

    US Agency for International Development — HTRAMS is a travel data collection system for GH that collects information on both the basic details of an employee's trips (destination, length, purpose, etc.) and...

  16. Supporting Multiple Cognitive Processing Styles Using Tailored Support Systems

    Energy Technology Data Exchange (ETDEWEB)

    Tuan Q. Tran; Karen M. Feigh; Amy R. Pritchett

    2007-08-01

    According to theories of cognitive processing style or cognitive control mode, human performance is more effective when an individual’s cognitive state (e.g., intuition/scramble vs. deliberate/strategic) matches his/her ecological constraints or context (e.g., utilize intuition to strive for a "good-enough" response instead of deliberating for the "best" response under high time pressure). Ill-mapping between cognitive state and ecological constraints are believed to lead to degraded task performance. Consequently, incorporating support systems which are designed to specifically address multiple cognitive and functional states e.g., high workload, stress, boredom, and initiate appropriate mitigation strategies (e.g., reduce information load) is essential to reduce plant risk. Utilizing the concept of Cognitive Control Models, this paper will discuss the importance of tailoring support systems to match an operator's cognitive state, and will further discuss the importance of these ecological constraints in selecting and implementing mitigation strategies for safe and effective system performance. An example from the nuclear power plant industry illustrating how a support system might be tailored to support different cognitive states is included.

  17. Supporting Multiple Cognitive Processing Styles Using Tailored Support Systems

    International Nuclear Information System (INIS)

    According to theories of cognitive processing style or cognitive control mode, human performance is more effective when an individual's cognitive state (e.g., intuition/scramble vs. deliberate/strategic) matches his/her ecological constraints or context (e.g., utilize intuition to strive for a 'good-enough' response instead of deliberating for the 'best' response under high time pressure). Ill-mapping between cognitive state and ecological constraints are believed to lead to degraded task performance. Consequently, incorporating support systems which are designed to specifically address multiple cognitive and functional states e.g., high workload, stress, boredom, and initiate appropriate mitigation strategies (e.g., reduce information load) is essential to reduce plant risk. Utilizing the concept of Cognitive Control Models, this paper will discuss the importance of tailoring support systems to match an operator's cognitive state, and will further discuss the importance of these ecological constraints in selecting and implementing mitigation strategies for safe and effective system performance. An example from the nuclear power plant industry illustrating how a support system might be tailored to support different cognitive states is included

  18. Bleeding following deep hypothermia and circulatory arrest in children.

    Science.gov (United States)

    Mossad, Emad B; Machado, Sandra; Apostolakis, John

    2007-03-01

    Deep hypothermic circulatory arrest (DHCA) is a technique of extracorporeal circulation commonly used in children with complex congenital heart defects undergoing surgical repairs. The use of profound cooling (20 degrees C) and complete cessation of circulation allow adequate exposure and correction of these complex lesions, with enhanced cerebral protection. However, the profound physiologic state of DHCA results in significant derangement of the coagulation system and a high incidence of postoperative bleeding. This review examines the impact of DHCA on bleeding and transfusion requirements in children and the pathophysiology of DHCA-induced platelet dysfunction. It also focuses on possible pharmacologic interventions to decrease bleeding following DHCA in children. PMID:17484172

  19. Safeguards -Safeguards system development support-

    International Nuclear Information System (INIS)

    This project mainly focused to technically support national safeguards inspection which is scheduled in the beginning of 1997. It includes non-destructive assay of nuclear fuels, analysis on inspection and environmental samples, remote monitoring of nuclear activities and its analysis, survey on remote sensing of satellite for safeguards application. Non-destructive assay of nuclear fuels dealt with development on verification of spent fuels with emphasis to fabrication of inspection tools with surveillance and gamma measurement on CANDU spent fuels. For sample analysis, study was carried out on process inspection sample analysis method. In addition to this, ultra low background laboratory was set up to execute environmental and swipe samples and sample treatment techniques including water, soil, plant, et al. were researched. Tritiums which were sampled around power plants were analysed. With cooperation of Satellite Technology Research Center of KAIST, use of civilian satellite imagery was surveyed. To train facility operators for safeguards, various technology on non-destructive assay was lectured to personnel of Korea Electric Power Corporation. And to enhance out capabilities, non-destructive assay training was done at Los Alamos National Lab. of U.S. through the agreement of MOST and DOE agreement, and information on DA technology was exchanged at Nuclear Material Control Center of Japan. (author). 22 tabs., 52 figs., 53 refs

  20. Seed systems support in Kenya

    OpenAIRE

    Munyi, Peter; Jonge, de, M.J.I.

    2015-01-01

    The threats of climate change and rising food prices have stirred renewed attention for seed and food security in Africa, inviting new thinking on the role of seed sector development in coping with these concerns. One conceptual framework that has gained attention is the Integrated Seed Sector Development (ISSD) approach. The ISSD approach has evolved as a response to the almost exclusive focus on formal seed systems in seed sector development programs. Instead, ISSD aims to recognize and sup...

  1. A Marketing Decision Support System for Retailers

    OpenAIRE

    Leonard M. Lodish

    1982-01-01

    A decision support system for planning marketing strategies and allocating resources for a multi-store retailer is described. This decision support system combines well-known model building and analysis methodology, sophisticated computer software, and attention to management's implementation needs in order to apply management science thinking to messy, high level strategy and forecasting problems. The system consists of a planning model, national campaign evaluation system, experimental anal...

  2. Novel Multi-Functional Life Support System

    OpenAIRE

    Webb, David P.; Jackson, Darren; Kasasbeh, Ehab S.; Bagai, Jayant; Zhao, David X.

    2010-01-01

    Concepts of cardiopulmonary support (CPS), extra-corporeal membrane oxygenation (ECMO), and ventricular support (VS) have been thoroughly studied and refined. These perfusion adjuncts often require multiple devices, skill sets, and significant financial burden to purchase, maintain, deploy, and use. We describe a novel system that is rapidly deployable, user-friendly, portable, safe, and economical. Over a 1-year period we have used a multi-functional life support system (MLS) in the cardiac ...

  3. Developing Sustainable Life Support System Concepts

    Science.gov (United States)

    Thomas, Evan A.

    2010-01-01

    Sustainable spacecraft life support concepts may allow the development of more reliable technologies for long duration space missions. Currently, life support technologies at different levels of development are not well evaluated against each other, and evaluation methods do not account for long term reliability and sustainability of the hardware. This paper presents point-of-departure sustainability evaluation criteria for life support systems, that may allow more robust technology development, testing and comparison. An example sustainable water recovery system concept is presented.

  4. Pathophysiological roles of peroxynitrite in circulatory shock

    OpenAIRE

    Szabó, Csaba; Módis, Katalin

    2010-01-01

    Peroxynitrite is a reactive oxidant produced from nitric oxide (NO) and superoxide, which reacts with proteins, lipids and DNA and promotes cytotoxic and pro-inflammatory responses. Here we overview the role of peroxynitrite in various forms of circulatory shock. Immunohistochemical and biochemical evidence demonstrate the production of peroxynitrite in various experimental models of endotoxic and hemorrhagic shock, both in rodents and in large animals. In addition, biological markers of pero...

  5. Biplane roentgen videometric system for dynamic, 60/sec, studies of the shape and size of circulatory structures, particularly the left ventricle.

    Science.gov (United States)

    Ritman, E. L.; Sturm, R. E.; Wood, E. H.

    1973-01-01

    An operator interactive video system for the measurement of roentgen angiographically outlined structures is described. Left ventricular volume and three-dimensional shapes are calculated from up to 200 pairs of diameters measured from ventriculograms at the rate of 60 pairs of biplane images per second. The accuracy and reproducibility of volumes calculated by the system were established by analysis of roentgenograms of inanimate objects of known volume and by comparison of left ventricular stroke volumes calculated by the system with the stroke volumes calculated by an indicator-dilution technique and an aortic root electromagnetic flowmeter. Computer-generated display of the large amounts of data obtained by the videometry system is described.

  6. Business Management System Support Analysis

    Science.gov (United States)

    Parikh, Jay

    2008-01-01

    The purpose of this research project was to develop a searchable database compiled with internal and external audit findings/observations. The data will correspond to the findings and observations from the date of Center-wide implementation of the ISO 9001-2000 standard to the present (2003-2008). It was derived and extracted from several sources and was in multiple formats. Once extracted, categorization of the findings/observations would be possible. The final data was mapped to the ISO 9001-2000 standard with the understanding that it will be displayed graphically. The data will be used to verify trends, associate risks, and establish timelines to identify strengths and weaknesses to determine areas of improvement in the Kennedy Space Center Business Management System Internal Audit Program.

  7. Indonesian Earthquake Decision Support System

    CERN Document Server

    Warnars, Spits

    2010-01-01

    Earthquake DSS is an information technology environment which can be used by government to sharpen, make faster and better the earthquake mitigation decision. Earthquake DSS can be delivered as E-government which is not only for government itself but in order to guarantee each citizen's rights for education, training and information about earthquake and how to overcome the earthquake. Knowledge can be managed for future use and would become mining by saving and maintain all the data and information about earthquake and earthquake mitigation in Indonesia. Using Web technology will enhance global access and easy to use. Datawarehouse as unNormalized database for multidimensional analysis will speed the query process and increase reports variation. Link with other Disaster DSS in one national disaster DSS, link with other government information system and international will enhance the knowledge and sharpen the reports.

  8. Cell and Tissue Organization in the Circulatory and Ventilatory Systems Volume 1 Signaling in Cell Organization, Fate, and Activity, Part A Cell Structure and Environment

    CERN Document Server

    Thiriet, Marc

    2011-01-01

    The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning.  The present volume is devoted to cellular events that allow adaptation to environmental conditions, particularly mechanotransduction. It begins with cell organization and a survey of cell types in the vasculatur...

  9. Maximally positive polynomial systems supported on circuits

    OpenAIRE

    Bihan, Frédéric

    2013-01-01

    A real polynomial system with support $\\calW \\subset \\Z^n$ is called {\\it maximally positive} if all its complex solutions are positive solutions. A support $\\calW$ having $n+2$ elements is called a circuit. We previously showed that the number of non-degenerate positive solutions of a system supported on a circuit $\\calW \\subset\\Z^n$ is at most $m(\\calW)+1$, where $m(\\calW) \\leq n$ is the degeneracy index of $\\calW$. We prove that if a circuit $\\calW \\subset \\Z^n$ supports a maximally positi...

  10. Operating-System Support for Distributed Multimedia

    OpenAIRE

    Mullender, Sape J.; Leslie, Ian M.; McAuley, Derek

    1994-01-01

    Multimedia applications place new demands upon processors, networks and operating systems. While some network designers, through ATM for example, have considered revolutionary approaches to supporting multimedia, the same cannot be said for operating systems designers. Most work is evolutionary in nature, attempting to identify additional features that can be added to existing systems to support multimedia. Here we describe the Pegasus project's attempt to build an integrated hardware and ope...

  11. Network support for system initiated checkpoints

    Science.gov (United States)

    Chen, Dong; Heidelberger, Philip

    2013-01-29

    A system, method and computer program product for supporting system initiated checkpoints in parallel computing systems. The system and method generates selective control signals to perform checkpointing of system related data in presence of messaging activity associated with a user application running at the node. The checkpointing is initiated by the system such that checkpoint data of a plurality of network nodes may be obtained even in the presence of user applications running on highly parallel computers that include ongoing user messaging activity.

  12. Vascular Endothelial Growth Factor Receptor Family in Ascidians, Halocynthia roretzi (Sea Squirt). Its High Expression in Circulatory System-Containing Tissues

    OpenAIRE

    Saeed Samarghandian; Masabumi Shibuya

    2013-01-01

    The vascular endothelial growth factor (VEGF)-VEGF Receptor (VEGFR) system is an important pathway for regulation of angiogenesis. However, its evolutionary development, particularly the step from invertebrates to vertebrates, is still largely unknown. Here, we molecularly cloned the VEGFR-like gene from Halocynthia roretzi, a species belonging to the Tunicata, the chordate subphylum recently considered the sister group of vertebrates. The cDNA encoded a homolog of human VEGFR, including the ...

  13. Infrastructure Support for Collaborative Pervasive Computing Systems

    DEFF Research Database (Denmark)

    Vestergaard Mogensen, Martin

    Collaborative Pervasive Computing Systems (CPCS) are currently being deployed to support areas such as clinical work, emergency situations, education, ad-hoc meetings, and other areas involving information sharing and collaboration.These systems allow the users to work together synchronously, but...... all characterized by unstable, volatile environments, either due to the underlying components changing or the nomadic work habits of users. A major challenge, for the creators of collaborative pervasive computing systems, is the construction of infrastructures supporting the system. The complexity of...... in order to build a supporting infrastructure for the envisioned collaborative pervasive computing system. Following an experimental computer science approach, where experiments are used both for theory testing and for exploration, we research the area of infrastructure support for collaborative...

  14. Method of determining the characteristics of circulatory systems using tracer particles, making the particles and radioactive particles for use in the method

    International Nuclear Information System (INIS)

    In the method described tracer particles consist of ion exchange resin cores labelled with suitable radioactive ions or with a nuclide excitable by X-rays, and have a non-leaching polymeric coating. The particles are introduced into the system and are detected by visual inspection, radiation detection or X-ray fluorescence techniques. The cores are labelled using conventional batch ion exchange techniques. Coated tracers are produced by contacting a monomer, preferably furfuryl alcohol, with cores bearing catalytic ions (hydroxyl or hydrogen) on the surface which catalyse the monomer to form a polymer. The tracer particles in a physiologically acceptable liquid carrier are useful in clinical and medical investigations of blood flow. They can also be used for flow measurement in chemical process control streams. (U.K.)

  15. Compactly Supported Curvelet-Type Systems

    DEFF Research Database (Denmark)

    Rasmussen, Kenneth Niemann; Nielsen, Morten

    curvelet-type systems with a prescribed nature such as compact support in direct space. The method consists of using the machinery of almost diagonal matrices to show that a system of curvelet molecules which is sufficiently close to curvelets constitutes a frame for curvelet-type spaces. Such a system of...

  16. Design thinking support: information systems versus reasoning

    OpenAIRE

    Pauwels, Pieter; Meyer, Ronald; Van Campenhout, Jan

    2013-01-01

    Numerous attempts have been made to conceive and implement appropriate information systems to support architectural designers in their creative design thinking processes. These information systems aim at providing support in very diverse ways: enabling designers to make diverse kinds of visual representations of a design, enabling them to make complex calculations and simulations which take into account numerous relevant parameters in the design context, providing them with loads of informati...

  17. Development of a simplified piping support system

    International Nuclear Information System (INIS)

    This paper presents the results of experimental and analytical studies for developing a simplified piping support system (SPSS) for nuclear power piping in place of snubbers. The basic concept of the SPSS is a passive seismic support system consisting of limit stops. Large gaps are provided to allow for free thermal expansion during normal plant operation while preventing excessive displacement during a seismic event. The results are part of a research and development program sponsored by EPRI. (orig./HP)

  18. Organ donation after circulatory death: the forgotten donor?

    OpenAIRE

    Rady, Mohamed Y; Verheijde, Joseph L; McGregor, Joan

    2006-01-01

    Donation after circulatory death (DCD) can be performed on neurologically intact donors who do not fulfill neurologic or brain death criteria before circulatory arrest. This commentary focuses on the most controversial donor-related issues anticipated from mandatory implementation of DCD for imminent or cardiac death in hospitals across the USA. We conducted a nonstructured review of selected publications and websites for data extraction and synthesis. The recommended 5 min of circulatory arr...

  19. Alpha particle problems in shielded support systems

    International Nuclear Information System (INIS)

    Alpha particle confinement is considered in the case of internal conductor systems with magnetically shielded supports. The treatment includes problems of energy transfer to the background plasma, the balance between radiation losses and alpha particle heating, mirror confinement in the main poloidal field, the cut-off and shielding conditions at the supports, ambipolar electric fields, wall interaction, and support location. With a proper and technically realizable choice of parameter values, it should become possible to achieve alpha particle heating as well as to manage the reactor technological problems due to alpha particle interaction with the supports. (Auth.)

  20. Computerised operator support systems for Indian NPPs

    International Nuclear Information System (INIS)

    Operator support and guidance forms an important part in the operation of any nuclear power plant. The operator support system for Indian Nuclear Power Plants (NPPs) reveal a continuous evolutionary history from conventional meters and recorders at Tarapur Atomic Power Station (TAPS) to the sophisticated computerised information systems at Kakrapar Atomic Power Plant (KAPP). This paper enumerates the role of Computerised Operator Information System (COIS), as it stands now, for Indian NPPs and also outlines the enhanced role such systems are expected to play for future projects. (author)

  1. Mortality of men caused by neoplasms; Mortality of women caused by neoplasms; Mortality of men caused by diseases of circulatory system; Mortality of women caused by diseases of circulatory system; Mortality of men caused by diseases of respiratory system; Mortality of women caused by diseases of respiratory system; Mortality of men caused by diseases of digestive system; Mortality of women caused by diseases of digestive system; Mortality of men caused by external causes; Mortality of women caused by external causes; 1 : 3 000 000

    International Nuclear Information System (INIS)

    Health condition of population was processed pursuing the data of the Statistical Office of the Slovak Republic and the Health for All international database (WHO, 1999). The analysis of causes of mortality of Slovak's population shows that: · two types of diseases are decisive: diseases of circulatory system and neoplasms, which cause death of almost four fifths of Slovak's population; · other diseases (diseases of respiratory and digestive systems, external causes - accidents, homicides, suicides, poisonings, etc.) cause death only to about a fifth of population. The occurrence of neoplastic diseases in the EU countries is slightly declining, the Czech Republic experienced even dramatic decrease, in contrary, an alarming increase of these diseases characterises Hungary. Slovakia compared to the rest of Europe is the second most threatened country following Hungary where almost 200 (in Slovakia it is about 160) out of 100,000 inhabitants in age below 64 years prematurely die annually from malign neoplasms. Even Ukrainians (150) are better off. About 2.5-fold less people die from cancer in Finland, Sweden or Norway compared to Slovakia. The low mean life expectancy of population of Slovakia is also reduced because of unfavourable health condition of the Roma ethnicity. (author)

  2. Information Systems as Support to Corporate Management

    Directory of Open Access Journals (Sweden)

    Florida Veljanoska

    2013-12-01

    Full Text Available The idea of this paper is to introduce the great support of information systems to the management activities of a corporation. Information system as a combination of information technology and people’s actions that support operations, management and decision making, involves four major types of systems: Transaction Management System, Management Information System, Decision-Support System and Executive Support System, and with that it is able to entail and support all business activities. In traditional firms these systems tend to be isolated from one another, and information does not flow seamlessly from one end of the organization to the other. However, in contemporary digital firms, the different types of systems are closely linked to one another. Taking into account the main areas of an enterprise, viewed from a functional perspective; manufacturing and production, sales and marketing, finance and accounting and human resources, one of the major challenges that enterprises face today, is putting together data from all of the departments in order to make information flow across the enterprise. These changes require powerful new systems that can integrate information from many different functional areas and organizational unites and coordinate firm activities with those of suppliers and other business partners. Those new systems or applications, also called as enterprise applications help to unify the firm’s structure and organization, provides more efficient operations and customer-driven business processes, help in achieving great efficiencies by automating parts of processes, contribute to completely rethinking processes, assist in all levels of management and in the perspective of technology, the corporation is represented as a unified platform. Although there are several challenges to build these systems, we strongly believe that there are extraordinary opportunities to use information systems to achieve business value and increase

  3. Rock support system development test plan

    International Nuclear Information System (INIS)

    The Test Plan has been prepared to support design activities for the development of a rock support system for a Nuclear Waste Repository in Basalt (NWRB). The rock support system is assumed to consist of a combination of shotcrete and rock bolts. The seven testing activities include mix development and physical testing of shotcrete, durability testing of shotcrete, durability testing of rock bolt grouts, field tests on rock bolts, field testing of shotcrete, and heated room test. The objective of the Test Plan is to develop required data through combined laboratory, field, and office studies for design and design validation of the rock support system. The overall Test Plan is developed to provide a logical progression from laboratory tests performed to characterize fundamental thermomechanical properties of shotcrete and grouts, to field tests on rock bolts and shotcrete, and in situ performance tests. 21 refs., 15 figs., 33 tabs

  4. Software Architecture Patterns for System Administration Support

    OpenAIRE

    Bijvank, Ronald; Wiersema, Wiebe; Köppe, Christian

    2013-01-01

    Many quality aspects of software systems are addressed in the existing literature on software architecture patterns. But the aspect of system administration seems to be a bit overlooked, even though it is an important aspect too. In this work we present three software architecture patterns that, when applied by software architects, support the work of system administrators: PROVIDE AN ADMINISTRATION API, SINGLE FILE LOCATION, and CENTRALIZED SYSTEM LOGGING. PROVIDE AN ADMINISTRATION API shoul...

  5. Clinical decision support system in dental implantology

    OpenAIRE

    Alexandra Polášková; Jitka Feberová; Taťjána Dostálová; Pavel Kříž; Michaela Seydlová

    2013-01-01

    Implantology is rapidly developing interdisciplinary field providing enormous amounts of data to be classified, evaluated and interpreted. The analysis of clinical data remains a big challenge, because each new system has specific requirements. The aim of study was prepare specific tool for treatment planning. Decision support system is built on Expert system. It is interactive software which provides clinical recommendations and treatment planning. Expert systems are knowledge-based computer...

  6. Circulatory abnormalities in cirrhosis with focus on neurohumoral aspects

    DEFF Research Database (Denmark)

    Møller, S; Henriksen, Jens Henrik Sahl

    1997-01-01

    -angiotensin-aldosterone system, and elevated circulating vasopressin, endothelin-1 may also be implicated in the hemodynamic counter-regulation in cirrhosis. Recent research has focused on the assertion that the hemodynamic and neurohumoral abnormalities in cirrhosis are part of a general circulatory dysfunction influencing the......Patients with cirrhosis exhibit characteristic hemodynamic changes with a hyperkinetic circulation and an abnormal distribution of the blood volume and neurohumoral regulation. Their plasma and noncentral blood volumes are increased, and the central and arterial blood volume and systemic vascular...... resistance are decreased. A peripheral arterial vasodilatation may be of pathogenic importance to the low systemic vascular resistance as it directly correlates to the degree of central hypovolemia. It may therefore be an important element in the development of the low arterial blood pressure and...

  7. Support Vector Machines for System Identification

    OpenAIRE

    Marconato, Anna; Gubian, Michele; Boni, Andrea; Petri, Dario

    2007-01-01

    In this document we propose the use of a widely known learning-from-examples paradigm, namely the Support Vector Machines for Regression (SVRs), for system identification problems. We start off with the identification of a simple linear system taken from the literature, and proceed with the non-linear case as a second step.

  8. A SWOT analysis of Planning Support Systems

    NARCIS (Netherlands)

    Vonk, G.; Geertman, S.; Schot, P.P.

    2007-01-01

    Insight into the strengths, weaknesses, opportunities, and threats (SWOT) of planning support systems (PSS) is fragmented between users and system developers. The lack of combined insights blocks development in the right direction and makes potential users hesitant to apply PSS in planning. This stu

  9. Operating-System Support for Distributed Multimedia

    NARCIS (Netherlands)

    Mullender, Sape J.; Leslie, Ian M.; McAuley, Derek

    1994-01-01

    Multimedia applications place new demands upon processors, networks and operating systems. While some network designers, through ATM for example, have considered revolutionary approaches to supporting multimedia, the same cannot be said for operating systems designers. Most work is evolutionary in n

  10. Nutritional support for the infant's immune system

    NARCIS (Netherlands)

    Niers, L.; Stasse-Wolthuis, M.; Rombouts, F.M.; Rijkers, G.T.

    2007-01-01

    Newborn babies possess a functional but immature immune system as a defense against a world teeming with microorganisms. Breast milk contains a number of biological, active compounds that support the infant's immune system. These include secretory immunoglobulin A (IgA), which confers specific prote

  11. Information systems to support Sizewell B

    International Nuclear Information System (INIS)

    This paper will describe the Information Systems used by PWR Project Group in the design, licensing and Project management of procurement, construction etc. of Sizewell B Power Station with particular emphasis on the Information Systems used to support Electrical and Control aspects of the Group's work. (author)

  12. Support system for Neutron Activation Analysis

    International Nuclear Information System (INIS)

    In the research reactor of JAERI, the Neutron Activation Analysis (NAA) has been utilized as a major part of an irradiation usage. To utilize NAA, research participants are always required to learn necessary technique. Therefore, we started to examine a support system that will enable to carry out INAA easily even by beginners. The system is composed of irradiation device, gamma-ray spectrometer and data analyzing instruments. The element concentration is calculated by using KAYZERO/SOLCOI software with the K0 standardization method. In this paper, we review on a construction of this INAA support system in JRR-3M of JAERI. (author)

  13. Operator Support System for Pressurized Water Reactor

    International Nuclear Information System (INIS)

    Operator Support System for Pressurized Water Reactor (OSSPWR) has been developed under the sponsorship of IAEA from August 1994. The project is being carried out by the Department of Engineering Physics, Tsinghua University, Beijing, China. The Design concepts of the operator support functions have been established. The prototype systems of OSSPWR has been developed as well. The primary goal of the project is to create an advanced operator support system by applying new technologies such as artificial intelligence (AI) techniques, advanced communication technologies, etc. Recently, the advanced man-machine interface for nuclear power plant operators has been developed. It is connected to the modern computer systems and utilizes new high performance graphic displays. (author). 6 refs, 4 figs

  14. PLM system support for modular product development

    DEFF Research Database (Denmark)

    Bruun, Hans Peter Lomholt; Mortensen, Niels Henrik; Harlou, Ulf;

    2015-01-01

    (PDM) and product lifecycle management (PLM) systems offer support by automating and managing some of the operational complexity of modular design activities. PLM system tools are used for handling a variety of product definitions, to manage workflow of development activities, and to measure relational...... properties such as cost and performance. Companies often use a PLM tool for management of CAD files, documents, and drawings, but they do not take advantage of the full potential of the PLM system to support the development activities of modular product designs. The key result of this paper is the...... description of an empirical tested approach using a visual product architecture representation in combination with a PLM system to support the development of a product family of products. The results from the study encompass new PLM capabilities for handling multiple product structures, visualising multiple...

  15. System Design for Transitional Aircraft Support

    Directory of Open Access Journals (Sweden)

    John P.T. Mo

    2014-01-01

    Full Text Available The Australian Defence Force and industry are undergoing significant changes in the way they work together in capability enhancement programs. There are capability gaps in maintaining and supporting current obligations during major asset acquisition, which has migrated into the front line of Royal Air Force Fighter Groups as a new capability. This paper examines a steady state support solution and argues that in order to interchange from one support solution to a new architecture there must be a period for transition, which may need its own interim business model and operational service. A preliminary study of several existing support solutions reveals the generic elements that need to be parameterized and traced through the support system architecture trajectory.

  16. Support systems of the orbiting quarantine facility

    Science.gov (United States)

    The physical support systems, the personnel management structure, and the contingency systems necessary to permit the Orbiting Quarantine Facility (OQF) to function as an integrated system are described. The interactions between the subsystems within the preassembled modules are illustrated. The Power Module generates and distributes electrical power throughout each of the four modules, stabilizes the OQF's attitude, and dissipates heat generated throughout the system. The Habitation Module is a multifunctional structure designed to monitor and control all aspects of the system's activities. The Logistics Module stores the supplies needed for 30 days of operation and provides storage for waste materials generated during the mission. The Laboratory Module contains the equipment necessary for executing the protocol, as well as an independent life support system.

  17. Dose calculation system for remotely supporting radiotherapy

    International Nuclear Information System (INIS)

    The dose calculation system IMAGINE is being developed keeping in mind remotely supporting external radiation therapy using photon beams. The system is expected to provide an accurate picture of the dose distribution in a patient body, using a Monte Carlo calculation that employs precise models of the patient body and irradiation head. The dose calculation will be performed utilising super-parallel computing at the dose calculation centre, which is equipped with the ITBL computer, and the calculated results will be transferred through a network. The system is intended to support the quality assurance of current, widely carried out radiotherapy and, further, to promote the prevalence of advanced radiotherapy. Prototypes of the modules constituting the system have already been constructed and used to obtain basic data that are necessary in order to decide on the concrete design of the system. The final system will be completed in 2007. (authors)

  18. Financial Effectiveness of Negotiation Support Systems

    Directory of Open Access Journals (Sweden)

    Christian NĂSULEA

    2015-06-01

    Full Text Available Implementing negotiation support systems requires the commitment of significant amounts of resources within the host organization. This paper looks at the effectiveness of investments in these systems, looking at some standard indicators for economic efficiency and the impact of these systems on an organization’s overall activities. This article is part of a research project spanning over a period of 3 years, aimed at developing a successful model for computer assisted negotiations.

  19. Lunar Surface Systems Supportability Technology Development Roadmap

    Science.gov (United States)

    Oeftering, Richard C.; Struk, Peter M.; Green, Jennifer L.; Chau, Savio N.; Curell, Philip C.; Dempsey, Cathy A.; Patterson, Linda P.; Robbins, William; Steele, Michael A.; DAnnunzio, Anthony; Meseroll, Robert; Quiter, John; Shannon, Russell; Easton, John W.; Madaras, Eric I.; BrownTaminger, Karen M.; Tabera, John T.; Tellado, Joseph; Williams, Marth K.; Zeitlin, Nancy P.

    2011-01-01

    The Lunar Surface Systems Supportability Technology Development Roadmap is a guide for developing the technologies needed to enable the supportable, sustainable, and affordable exploration of the Moon and other destinations beyond Earth. Supportability is defined in terms of space maintenance, repair, and related logistics. This report considers the supportability lessons learned from NASA and the Department of Defense. Lunar Outpost supportability needs are summarized, and a supportability technology strategy is established to make the transition from high logistics dependence to logistics independence. This strategy will enable flight crews to act effectively to respond to problems and exploit opportunities in an environment of extreme resource scarcity and isolation. The supportability roadmap defines the general technology selection criteria. Technologies are organized into three categories: diagnostics, test, and verification; maintenance and repair; and scavenge and recycle. Furthermore, "embedded technologies" and "process technologies" are used to designate distinct technology types with different development cycles. The roadmap examines the current technology readiness level and lays out a four-phase incremental development schedule with selection decision gates. The supportability technology roadmap is intended to develop technologies with the widest possible capability and utility while minimizing the impact on crew time and training and remaining within the time and cost constraints of the program.

  20. Using Visualization in Cockpit Decision Support Systems

    Energy Technology Data Exchange (ETDEWEB)

    Aragon, Cecilia R.

    2005-07-01

    In order to safely operate their aircraft, pilots must makerapid decisions based on integrating and processing large amounts ofheterogeneous information. Visual displays are often the most efficientmethod of presenting safety-critical data to pilots in real time.However, care must be taken to ensure the pilot is provided with theappropriate amount of information to make effective decisions and notbecome cognitively overloaded. The results of two usability studies of aprototype airflow hazard visualization cockpit decision support systemare summarized. The studies demonstrate that such a system significantlyimproves the performance of helicopter pilots landing under turbulentconditions. Based on these results, design principles and implicationsfor cockpit decision support systems using visualization arepresented.

  1. Advanced Life Support System Value Metric

    Science.gov (United States)

    Jones, Harry W.; Rasky, Daniel J. (Technical Monitor)

    1999-01-01

    The NASA Advanced Life Support (ALS) Program is required to provide a performance metric to measure its progress in system development. Extensive discussions within the ALS program have led to the following approach. The Equivalent System Mass (ESM) metric has been traditionally used and provides a good summary of the weight, size, and power cost factors of space life support equipment. But ESM assumes that all the systems being traded off exactly meet a fixed performance requirement, so that the value and benefit (readiness, performance, safety, etc.) of all the different systems designs are considered to be exactly equal. This is too simplistic. Actual system design concepts are selected using many cost and benefit factors and the system specification is defined after many trade-offs. The ALS program needs a multi-parameter metric including both the ESM and a System Value Metric (SVM). The SVM would include safety, maintainability, reliability, performance, use of cross cutting technology, and commercialization potential. Another major factor in system selection is technology readiness level (TRL), a familiar metric in ALS. The overall ALS system metric that is suggested is a benefit/cost ratio, SVM/[ESM + function (TRL)], with appropriate weighting and scaling. The total value is given by SVM. Cost is represented by higher ESM and lower TRL. The paper provides a detailed description and example application of a suggested System Value Metric and an overall ALS system metric.

  2. Intelligent systems supporting the control room operators

    International Nuclear Information System (INIS)

    The operational experience obtained with the various applications of the systems discussed in this paper shows that more consequent use of the systems will make detection and management of disturbances still more efficient and faster. This holds true both for a low level of process automation and for power plants with a high level of automation. As for conventional power plants, the trend clearly is towards higher degrees of automation and consequent application of supporting systems. Thus, higher availability and rapid failure management are achieved, at low effects on normal operation. These systems are monitoring and process control systems, expert systems, and systems for optimal use of the equipment, or systems for post-incident analyses and computer-assisted on-shift protocols, or operating manuals. (orig./CB)

  3. Influence of nitrous oxide pneumoperitoneum on the circulatory and respiratory systems of piglets%氧化亚氮气腹对新生猪循环、呼吸功能影响的实验研究

    Institute of Scientific and Technical Information of China (English)

    于怡; 高萱; 吕志葆

    2011-01-01

    Objective To study the influence of nitric oxide (N2O) pneumoperitoneum on the circulatory and respiratory systems of piglets.Methods Fourteen piglets,which weighted 2-4 kilograms and aged 7-14 days old,were equally and randomly divided into control group and N2O pneumoperitoneum group.On the anesthetized piglets of the N2O group,N2O pneumoperitoneum was induced by inflate the peritoneal cavity with N2O.Monitoring parameters included heart rate (HR),stroke volume index (SVI),cardiac index (CI),mean arterial pressure (MAP),central venous pressure (CVP),mean pulmonary arterial pressure (MPAP),systemic vascular resistance index (SVRI),dP/dtmax,partial pressure of carbon dioxide in arterial blood (PaCO2),partial pressure of oxygen in arterial blood (PaO2),arterial oxygen saturation (SaO2),concentration of HCO3- (HCO3-) in arterial blood and blood pH value (pH).The monitoring parameters were collected 5 minutes before N2O pneumoperitoneum inflation,15,30,60,and 120 min after N2 O pneumoperitoneum inflation and 60 min after pneumoperitoneum deflation.Results Hemodynamic and respiratory parameters of the control piglets were constantly normal.Compared with the control piglets,MPAP (26.29±2.57),PaCO2 (41.00±2.20),PaO2 (172.14± 1.57) and SVRI (2923.00 ± 115.70) of the N2O pneumoperitoneum piglets increased (P<0.05).HR (113.57 ± 3.23),dP/dtmax (432.43±36.61),MAP (75.00 ± 4.27),SVI ( 15.00±0.76) and CI (1.98±0.11) of N2O pneumoperitoneum piglets decreased (P<0.05).Conclusions Two hours' N2O pneumoperitoneum changes some circulatory parameters of piglets.%目的 建立新生猪气腹模型,观察人工N2O气腹时新生猪血流动力学及呼吸指标的变化规律.方法 乳猪14头,年龄7~14 d,体重2~4 kg.分为2组,对照组(CON组)7头,N2O气腹组(N2O组)7头,监测时间点为麻醉稳定后气腹开始前5 min,气腹开始后15 min、30 min、60min、120min,放气后60min.监测指标为:心率(HR)、每搏输出量指数(SVI)、心输出量指

  4. Support for User Interfaces for Distributed Systems

    Science.gov (United States)

    Eychaner, Glenn; Niessner, Albert

    2005-01-01

    An extensible Java(TradeMark) software framework supports the construction and operation of graphical user interfaces (GUIs) for distributed computing systems typified by ground control systems that send commands to, and receive telemetric data from, spacecraft. Heretofore, such GUIs have been custom built for each new system at considerable expense. In contrast, the present framework affords generic capabilities that can be shared by different distributed systems. Dynamic class loading, reflection, and other run-time capabilities of the Java language and JavaBeans component architecture enable the creation of a GUI for each new distributed computing system with a minimum of custom effort. By use of this framework, GUI components in control panels and menus can send commands to a particular distributed system with a minimum of system-specific code. The framework receives, decodes, processes, and displays telemetry data; custom telemetry data handling can be added for a particular system. The framework supports saving and later restoration of users configurations of control panels and telemetry displays with a minimum of effort in writing system-specific code. GUIs constructed within this framework can be deployed in any operating system with a Java run-time environment, without recompilation or code changes.

  5. Clinical Productivity System - A Decision Support Model

    CERN Document Server

    Bennett, Casey C

    2012-01-01

    Purpose: This goal of this study was to evaluate the effects of a data-driven clinical productivity system that leverages Electronic Health Record (EHR) data to provide productivity decision support functionality in a real-world clinical setting. The system was implemented for a large behavioral health care provider seeing over 75,000 distinct clients a year. Design/methodology/approach: The key metric in this system is a "VPU", which simultaneously optimizes multiple aspects of clinical care. The resulting mathematical value of clinical productivity was hypothesized to tightly link the organization's performance to its expectations and, through transparency and decision support tools at the clinician level, affect significant changes in productivity, quality, and consistency relative to traditional models of clinical productivity. Findings: In only 3 months, every single variable integrated into the VPU system showed significant improvement, including a 30% rise in revenue, 10% rise in clinical percentage, a...

  6. Designing a mobile academic peer support system

    OpenAIRE

    AlSugair, Balsam; Hopkins, Gail; FitzGerald, Elizabeth; Brailsford, Tim

    2012-01-01

    In this paper, we discuss work in progress into the design of a mobile academic peer support system that enables 11-to-14 year old children to request and provide academic help to each other. Our proposed system was designed based on background research into the areas of peer learning, child development, help-seeking and academic motivation. Several methods, such as focus groups, interviews and Wizard of Oz, were used during the requirements gathering and initial testing stages. The proposed ...

  7. A decision support system for forensic entomology

    OpenAIRE

    Morvan, Gildas; Jolly, Daniel; Dupont, Daniel; Kubiak, Philippe

    2007-01-01

    International audience This paper presents a multiagent-based model of insect development on a dead body and a three layers Decision Support System architecture able to perform retrodictive (abductive) reasoning from multiagent-based models or more generally, complex systems models. This architecture is used in order to compute post-mortem intervals from entomological data sampled on cadavers. Knowing the exact time of a death is fundamental in criminal investigations. Thus, it is necessar...

  8. Life support system development in West Germany.

    Science.gov (United States)

    Skoog, A I

    1982-12-01

    The delivery of fully qualified Environmental Control and Life Support System (ECLS) flight hardware for the Spacelab Flight Unit was completed in 1979, and the first Spacelab flight is scheduled for mid 1983. With Spacelab approaching its operational stage, ESA has initiated the Follow-on Development Programme. The future evolution of Spacelab elements in a continued U.S./European cooperation is obviously linked to the U.S. STS evolution and leads from the sortie-mode improvements (Initial Step) towards pallet systems and module applications in unmanned and manned space platforms (Medium and Far Term Alternatives). Extensive studies and design work have been accomplished on life support systems for Life Sciences Laboratories (Biorack) in Spacelab (incubators and holding units for low vertebrates). Future long term missions require the implementation of closed loop life support systems and in order to meet the long range development cycle feasibility studies have been performed. Terrestrial applications of the life support technologies developed for space have been successfully implemented. PMID:11541695

  9. Life support system development in West Germany

    Science.gov (United States)

    Skoog, A. Ingemar

    The delivery of fully qualified Environmental Control and Life Support System (ECLS) flight hardware for the Spacelab Flight Unit was completed in 1979, and the first Spacelab flight is scheduled for mid 1983. With Spacelab approaching its operational stage, ESA has initiated the Follow-on Development Programme. The future evolution of Spacelab elements in a continued U.S./European cooperation is obviously linked to the U.S. STS evolution and leads from the sortie-mode improvements (Initial Step) towards pallet systems and module applications in unmanned and manned space platforms (Medium and Far Term Alternatives). Extensive studies and design work have been accomplished on life support systems for Life Sciences Laboratories (Biorack) in Spacelab (incubators and holding units for low vertebrates). Future long term missions require the implementation of closed loop life support systems and in order to meet the long range development cycle feasibility studies have been performed. Terrestrial applications of the life support technologies developed for space have been successfully implemented.

  10. ROI Calculations for Electronic Performance Support Systems.

    Science.gov (United States)

    Altalib, Hasan

    2002-01-01

    Discusses the importance of calculating the return on investment (ROI) for electronic performance support systems, beginning with the practical issues of identifying what will be measured and then assigning costs and benefits to each variable in monetary terms. Suggests the challenge is in defining and quantifying the real business benefits.…

  11. Electronic Performance Support Systems and Technological Literacy

    Science.gov (United States)

    Maughan, George R.

    2005-01-01

    Electronic performance support systems (EPSS) can provide alternative learning opportunities to supplement traditional classroom or training strategies. Today's students may benefit from educational settings and strategies that they will use in the future. In using EPSS to nurture the development of technological literacy, workers and students can…

  12. Novel use of the AngioVac® system to remove thrombus during simultaneous extracorporeal membrane oxygenation life support.

    Science.gov (United States)

    Griffith, Kevin E; Jenkins, Eric; Copenhaver, William; Williams, David M

    2016-03-01

    Extracorporeal membrane oxygenation (ECMO) was introduced to clinical medicine over 40 years ago. While initially used as a treatment for acute respiratory failure in infants, the use of ECMO has grown to include respiratory and circulatory failure in both children and adults, cardiogenic shock, pulmonary embolism, sepsis, trauma, malignancy, pulmonary hemorrhage and as a treatment for hypothermic drowning.(1) Recent technological improvements in ECMO circuitry make it possible to minimize anticoagulation of the ECMO patient, decreasing the incidence of bleeding. Thrombus deposition within the ECMO circuit can be a life-threating complication. ECMO circuit thrombus can be contained in the circuit, adherent to cannula and deposited within the patient. The ability to remove thrombus while the patient remains on ECMO support could be a life-saving measure for some patients. The present case report outlines use of the AngioVac(®) thrombus removal system in concert with ECMO to remove a large thrombus adherent to an ECMO cannula. PMID:26034197

  13. Remote mobile communication in safety support system

    International Nuclear Information System (INIS)

    Safety Support System (SSS) is a computerized operator support system for nuclear power plants, which is now under development. The concept of SSS covers 1) earlier detection of failure symptom and prediction of its influence to the plant operation, 2) improved transparency and robustness of plant control systems, 3) advanced human-machine interface and communication. The authors have been working on the third concept and proposed a remote mobile communication system called Plant Communication System (PCS). PCS aims to realize convenient communication between main control room and other areas such as plant local areas and site offices, using Personal Handyphone System (PHS) and wireless LAN (Local Area Network). PCS can transmit not only data but also graphic displays and dynamic video displays between the main control room and plant local areas. MPEG4 (Moving Picture Experts Group 4) technology is utilized in video data compression and decompression. The authors have developed the special multiplexing unit that connects PHS Cell Stations (CSs) and exiting coaxial cables. Voice recognition and announcement capability is also realized in the system, which enables verbal retrieval of information in the computer systems in the main control room from local areas. (author)

  14. Knowledge representation for decision support systems

    International Nuclear Information System (INIS)

    This book is organized into three sections in accordance with the structure of the conference program. First section contains four major papers which were commissioned by the Programme Committee to set the tone for the conference and to provide a structured source of relevant material from contributing disciplines. The second section contains specific papers submitted to the conference, and concerned with the following topics of specific interest: epistemological issues for decision support systems (DSS), capturing organizational knowledge for DSS, complementarity between human and formal DSS, and representations for adaption. The third section contains the short papers on any topic of relevance to the theme of the conference. It is hoped that the two working conferences organized by WG 8.3 will contribute to the development of a coherent knowledge and understanding of the class of computerized information systems called Decision Support Systems. (Auth.)

  15. Implementation of Business Game Activity Support System

    Institute of Scientific and Technical Information of China (English)

    TANABU Motonari

    2004-01-01

    Business game can be used not only as an educational tool for the development of decision making ability, but also can be used for supporting the knowledge creation activity in organizations. In this paper, some conceptual considerations to meanings of the business game in the knowledge creation activity by using the knowledge creation theory and other related theories are given,and business game activity concept which refers to game play and development is proposed. Then focusing on the business game activity as an instantiation of the knowledge creation activity, and a Web based gaming activity support system based on the former system called YBG that enables us to play and develop many business games through the standard web browser is proposed. This system also provides us a lot of opportunities to play and develop the business games over business game communities.

  16. Impulse: Memory System Support for Scientific Applications

    Directory of Open Access Journals (Sweden)

    John B. Carter

    1999-01-01

    Full Text Available Impulse is a new memory system architecture that adds two important features to a traditional memory controller. First, Impulse supports application‐specific optimizations through configurable physical address remapping. By remapping physical addresses, applications control how their data is accessed and cached, improving their cache and bus utilization. Second, Impulse supports prefetching at the memory controller, which can hide much of the latency of DRAM accesses. Because it requires no modification to processor, cache, or bus designs, Impulse can be adopted in conventional systems. In this paper we describe the design of the Impulse architecture, and show how an Impulse memory system can improve the performance of memory‐bound scientific applications. For instance, Impulse decreases the running time of the NAS conjugate gradient benchmark by 67%. We expect that Impulse will also benefit regularly strided, memory‐bound applications of commercial importance, such as database and multimedia programs.

  17. Development of decommissioning engineering support system for fugen. Development of support system during actual dismantlement works

    International Nuclear Information System (INIS)

    The Advanced Thermal Reactor, Fugen Nuclear Power Station was permanently shut down in March 2003, and is now preparing for decommissioning. We have been developing Decommissioning Engineering Support System (DEXUS) aimed at planning optimal dismantlement process and carrying out dismantlement work safely and precisely. DEXUS consists of 'decommissioning planning support system' and 'dismantling support system'. The dismantling support system is developed aiming at using during actual dismantling work. It consists of three subsystems such as 'Worksite Visualization System', 'Dismantling Data Collection System' and 'Generated Waste Management System'. 'Worksite Visualization System' is a support system designed to provide the necessary information to workers during actual dismantlement works. And this system adopts AR (Augmented Reality) technology, overlapping calculation information into real world. 'Dismantling Data Collection System' is to collect necessary data for improving accuracy of decommissioning planning by evaluating work content and worker equipage, work time for dismantlement works. 'Generated Waste Management system' is a system recording necessary information by attaching the barcode to dismantled wastes or the containers. We can get the information of generated waste by recording generation place, generated time, treatment method and the contents. These subsystems enable to carry out reasonable and safe decommissioning of Fugen. In addition, we expect that those systems will be used for decommissioning of other nuclear facilities in the future. (authors)

  18. Structural disproportions in regional medical standards in treatment of blood circulatory disorders

    OpenAIRE

    Sazanova G.Yu.

    2012-01-01

    The research goal is to consider the opinion of physicians about the financial medical assistance standards to patients with blood circulatory disorders. Materials and methods: 530 doctors of different specialties were interviewed. Some sociological and statistical methods were used in the study. Results: The majority of respondents (83%) considered that it was necessary to coordinate financial support of diagnostic and treatment expenditures with the standards of the regional program of rend...

  19. Recent advances in computational methodology for simulation of mechanical circulatory assist devices

    OpenAIRE

    Marsden, Alison L.; Bazilevs, Yuri; Long, Christopher C.; Behr, Marek

    2014-01-01

    Ventricular assist devices (VADs) provide mechanical circulatory support to offload the work of one or both ventricles during heart failure. They are used in the clinical setting as destination therapy, as bridge to transplant, or more recently as bridge to recovery to allow for myocardial remodeling. Recent developments in computational simulation allow for detailed assessment of VAD hemodynamics for device design and optimization for both children and adults. Here, we provide a focused revi...

  20. Apollo 14 flight support and system performance

    Science.gov (United States)

    Rice, R. R.

    1971-01-01

    The Apollo 13 incident and subsequent oxygen tank redesign for Apollo 14 placed unique requirements on the flight support activity. A major part of this activity was the integration of the various analytical efforts into a single team function. Additionally, the first flight of the redesigned system without an orbital test required an extensive analytical base. The support team philosophy, objectives, and organization are presented. Various analytical tools that were used during the flight are discussed. Investigations made during the postflight period are considered and their impact upon subsequent flights shown.

  1. Operator support system using computational intelligence techniques

    Energy Technology Data Exchange (ETDEWEB)

    Bueno, Elaine Inacio, E-mail: ebueno@ifsp.edu.br [Instituto Federal de Educacao, Ciencia e Tecnologia de Sao Paulo (IFSP), Sao Paulo, SP (Brazil); Pereira, Iraci Martinez, E-mail: martinez@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    Computational Intelligence Systems have been widely applied in Monitoring and Fault Detection Systems in several processes and in different kinds of applications. These systems use interdependent components ordered in modules. It is a typical behavior of such systems to ensure early detection and diagnosis of faults. Monitoring and Fault Detection Techniques can be divided into two categories: estimative and pattern recognition methods. The estimative methods use a mathematical model, which describes the process behavior. The pattern recognition methods use a database to describe the process. In this work, an operator support system using Computational Intelligence Techniques was developed. This system will show the information obtained by different CI techniques in order to help operators to take decision in real time and guide them in the fault diagnosis before the normal alarm limits are reached. (author)

  2. Supporting multiple control systems at Fermilab

    Energy Technology Data Exchange (ETDEWEB)

    Nicklaus, Dennis J.; /Fermilab

    2009-10-01

    The Fermilab control system, ACNET, is used for controlling the Tevatron and all of its pre-accelerators. However, other smaller experiments at Fermilab have been using different controls systems, in particular DOOCS and EPICS. This paper reports some of the steps taken at Fermilab to integrate support for these outside systems. We will describe specific tools that we have built or adapted to facilitate interaction between the architectures. We also examine some of the difficulties that arise from managing this heterogeneous environment. Incompatibilities as well as common elements will be described.

  3. Functional Fuzzy Based Autism Assessment Support System

    Directory of Open Access Journals (Sweden)

    Anju Pratap

    2014-10-01

    Full Text Available Childhood autism is one of the most common developmental disorders in children, whose disabilities generally tend to follow through adulthood. The therapy given to an autistic child depends on its accurate assessment, which is a challenging clinical decision making problem. This paper describes the application of functional fuzzy model in autism assessment support systems. The fuzzy model uses Takagi-Sugeno Kang (TSK type of inference mechanism for supporting the assessment. A rule based single input-single output first order functional fuzzy model has been applied to a set of real world data and the experimental results were compared with the conventional autism assessment method. The results demonstrate that the proposed method works better in putting the borderline between autistic grades in terms of accuracy. Thus the functional fuzzy model can support in assessing the grade of childhood autism with certainty.

  4. Decommissioning support system, using RFID and USN

    International Nuclear Information System (INIS)

    RFID and USN are key technology in the ubiquitous computing systems. Actual physical environmental information can be used to remote control systems and management using various sensor technology and wireless network. These are used to managing physical distribution systems, complex monitoring environments such as fire detecting and various environments in the field of u-healthcare. Recently, decontamination and dismantling for nuclear plant have increasing interest after Fucushima nuclear accident. In this paper, a decommissioning support system is suggested for an effective management and control of work efficiency and of worker's status. This system makes effective real-time monitoring worker's location, work status and radiation exposure and effective response for worker's safety and emergency situation

  5. Decommissioning support system, using RFID and USN

    Energy Technology Data Exchange (ETDEWEB)

    Cho, W. H.; Park, S. K.; Choi, Y. D.; Lee, K. I.; Moon, J. K. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-05-15

    RFID and USN are key technology in the ubiquitous computing systems. Actual physical environmental information can be used to remote control systems and management using various sensor technology and wireless network. These are used to managing physical distribution systems, complex monitoring environments such as fire detecting and various environments in the field of u-healthcare. Recently, decontamination and dismantling for nuclear plant have increasing interest after Fucushima nuclear accident. In this paper, a decommissioning support system is suggested for an effective management and control of work efficiency and of worker's status. This system makes effective real-time monitoring worker's location, work status and radiation exposure and effective response for worker's safety and emergency situation

  6. Decision support system for structure synthesis of monitoring systems

    Directory of Open Access Journals (Sweden)

    Skatkov A. V.

    2008-04-01

    Full Text Available The paper is concerned with a structure synthesis of monitoring systems. In the article a decision support system for such synthesis was proposed and described. In the first phase of the process, the proposed classification of monitoring systems is used. Then adaptive algorithms, simulation and analytic modeling are used. The results of studies carried out by means of the proposed program are represented. The topicality of proposed approach was demonstrated. It should be mentioned, that algorithms were thoroughly described, the computing experiments were carried out. The authors believe that the proposed decision support system has many advantages and, consequently, is very useful in structure synthesis of monitoring systems.

  7. DECISION SUPPORT SYSTEMS FOR LOGISTICS MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Pere Tumbas

    2007-12-01

    Full Text Available The environment where managers make decisions has been significantly changed ttiese years. Today, organizations design their products in one country, purchase of materials and raw materials in the other one, production is done in the third country, and finished products are brought out in many countries in the world. Logistics, as a transaction intensive function mutually connect these substantially different business processes and enables more effective and efficient management of the long logistics chains. In realizing such a task, the intensive use of infomiation technologies that provide timely transaction processing and give support in decisionmaking processes is especially important for logistics. The work reviews information systems development in the field of logistics, and a special attention is paid to the conceptual level of the global structure in decision support systems (DSS. Possible contents of identified subsystems are cited and potential development trends of its application are discussed.

  8. Computer systems to support census geography.

    Science.gov (United States)

    Deecker, G; Cunningham, R; Kidd, K

    1986-01-01

    The development of computer systems that support the geography of the census in Canada is described. The authors "present proposals for the 1991 Census that increase the level of automation, whether the geography changes or not. In addition, opportunities for change and improvement, should the geography change, are outlined. To minimize the risks involved, it is important to give these different proposals serious consideration early in the planning of a census." PMID:12341362

  9. DECISION SUPPORT SYSTEM FOR PRECISION FARMING

    OpenAIRE

    Harmandeep Singh; Nitika Sharma

    2013-01-01

    A decision support system for precision farming is designed to assist farmers, agricultural experts, research workers or any intellectuals with guidance in making various farming related decisions and help them to access, display and analyze data that have geographic content and meaning. The concept of precision farming is not only related with the use of technologies but it is also about the five R’s that is use of right input (nutrients, water, fertilizer, money, machinery etc.), at the rig...

  10. Decision Support System Mine -The Management Model

    OpenAIRE

    Kaden, S.; Michels, I.; Tiemer, K.

    1986-01-01

    The Decision Support System MINE has been developed for the analysis of regional water policies in open-pit lignite mining areas. It is based on a two-level model approach. The first-level planning model is used for the estimation of rational strategies of long-term development applying dynamic multi-criteria analysis. Therefor simplified submodels are used for a rough time discretization (yearly time steps and larger). The second-level management model considers managerial/operational aspect...

  11. A Flexible Nurse Scheduling Support System

    OpenAIRE

    Ozkarahan, Irem

    1987-01-01

    Scheduling nursing personnel in hospitals is very complex because of the variety of conflicting interests and objectives. Also, demand varies 24-hour a day 7-day a week, is skill specific and hard to forecast. In the face of this complexity, the present nurse scheduling models have met with little success. In this paper, we propose a more flexible decision support system that will satisfy the interests of both hospitals and nurses through alternative models that attempt to accommodate flexibl...

  12. Westinghouse computer-based operator support systems

    International Nuclear Information System (INIS)

    Modern plant computers provide access to a large number of plant measured and calculated data. These data can be used by a number of application programs or systems to support the operator's work in the control room. This paper provides an overview of three such systems developed by Westinghouse: an Advanced Alarm Management System (AWARE), a Revolutionary Core Monitoring Program (BEACON), and a Computerized Procedures Package (COMPRO). The AWARE alarm management system was originally designed to be part of the Advanced Control Room design for future nuclear plants. It has been tailored for backfit to operating plants and can be installed during a single plant outage. One of the design goals of the system is to have no alarm in the control room following a reactor trip, as long as the systems are behaving as designed. AWARE can be installed as a full backfit or as a partial backfit using existing annunciator tiles, or provide separate alarm treatment to the plant computer. The BEACON system is a core monitoring, analysis, and prediction tool that provides unparalleled power for understanding and planning core operation. BEACON calculates three-dimensional core power distributions on-line, using an advanced core model. The core model is always in agreement with actual operation because it is continuously updated with measurements obtained from conventional plant instrumentation. Power distribution information is visualized through advanced color graphics to provide users with immediate feedback and comprehensive understanding of core behaviour. The COMPRO system supports the operator in the application of the plant procedures. COMPRO utilizes the written procedures as the basis for textual displays, prompts the operator to the actions to take and provides relevant information about the state to plant parameters. This system guides the user step by step through the plant procedures by monitoring the appropriate plant data and by identifying the recommended course of

  13. Performance support systems and artificial intelligent considerations

    International Nuclear Information System (INIS)

    Intelligent performance support systems (PSS) for reactor operations have been discussed, but none is operating yet. The features desired are human-centred design, intelligent behaviour, and real-time performance. PSS derive their origins from the realization that intelligent open-loop complex plant control involves consideration of the human component as well as the machine part of the system. Also , for the PSS to be effective, real-time operating capability is necessary. In this context, the present paper examines the role of artificial intelligence in PSS. 22 refs., 3 figs

  14. The VST secondary mirror support system

    Science.gov (United States)

    Schipani, P.; Perrotta, F.; Molfese, C.; Caputi, O.; Ferragina, L.; Marty, L.; Capaccioli, M.; Gallieni, D.; Fumi, P.; Anaclerio, E.; Lazzarini, P.; De Paris, G.

    2008-07-01

    The VST telescope is equipped with an active optics system based on a wavefront sensor, a set of axial actuators to change the primary mirror shape and a secondary mirror positioner stage. The secondary mirror positioning capability allows the correction of defocus and coma optical aberrations, mainly caused by incorrect relative positions of the optics. The secondary mirror positioner is a 6-6 Stewart platform (also called "hexapod"). It is a parallel robot with a mobile platform moved by 6 linear actuators acting simultaneously. This paper describes the secondary mirror support system and the current status of the work.

  15. Apollo portable life support system performance report

    Science.gov (United States)

    Carson, M. A.

    1972-01-01

    The performance of the Apollo portable life support system (PLSS) on actual lunar missions is discussed. Both subjective comments by the crewmen and recorded telemetry data are evaluated although emphasis is on the telemetry data. Because the most important information yielded by the PLSS deals with determination of crewman metabolic rates, these data and their interpretation are explained in detail. System requirements are compared with actual performance, and the effect of performance margins on mission planning are described. Mission preparation testing is described to demonstrate how the mission readiness of the PLSS and the crewmen in verified, and to show how the PLSS and the crewmen are calibrated for mission evaluation.

  16. A COMPUTERIZED OPERATOR SUPPORT SYSTEM PROTOTYPE

    Energy Technology Data Exchange (ETDEWEB)

    Thomas A. Ulrich; Roger Lew; Ronald L. Boring; Ken Thomas

    2015-03-01

    A computerized operator support system (COSS) is proposed for use in nuclear power plants to assist control room operators in addressing time-critical plant upsets. A COSS is a collection of technologies to assist operators in monitoring overall plant performance and making timely, informed decisions on appropriate control actions for the projected plant condition. A prototype COSS was developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based on four underlying elements consisting of a digital alarm system, computer-based procedures, piping and instrumentation diagram system representations, and a recommender module for mitigation actions. The initial version of the prototype is now operational at the Idaho National Laboratory using the Human System Simulation Laboratory.

  17. Bioregenerative life support systems for microgravity

    Science.gov (United States)

    Nevill, Gail E., Jr.; Hessel, Michael I., Jr.; Rodriguez, Jose; Morgan, Steve (Editor)

    1993-01-01

    NASA's Controlled Ecological Life Support System (CELSS) project centers on growing plants and recycling wastes in space. The current version of the biomass production chamber (BPC) uses a hydroponic system for nutrient delivery. To optimize plant growth and conserve system resources, the content of the nutrient solution which feeds the plants must be constantly monitored. The macro-nutrients (greater than ten ppm) in the solution include nitrogen, phosphorous, potassium, calcium, magnesium, and sulphur; the micro-nutrients (less than ten ppm) include iron, copper, manganese, zinc, and boron. The goal of this project is to construct a computer-controlled system of ion detectors that will accurately measure the concentrations of several necessary ions in solution. The project focuses on the use of a sensor array to eliminate problems of interference and temperature dependence.

  18. Senescent Changes in Cerebrospinal Fluid Circulatory Physiology and Their Role in the Pathogenesis of Normal-tension Glaucoma

    NARCIS (Netherlands)

    Wostyn, Peter; De Groot, Veva; Van Dam, Debby; Audenaert, Kurt; De Deyn, Peter Paul

    2013-01-01

    PURPOSE: To evaluate the evidence supporting a role for senescent changes in cerebrospinal fluid (CSF) circulatory physiology in the pathogenesis of normal-tension glaucoma (NTG). DESIGN: Literature review and personal perspective of the authors. METHODS: Analysis of selected articles in the peer-re

  19. HEMOS: an expert support system prototype for forecasting blood requirements for Marine Corps medical support/

    OpenAIRE

    Greenauer, Michael A.

    1988-01-01

    Research was conducted to demonstrate the applicability of artificial intelligence techniques to the problem of estimating blood resupply requirements in Navy medical units supporting Marine Corps commands engaged in combat operations. Prototyping methodology was used to develop a combination expert system and decision support system, termed an expert support system, which was named HEMOS (Hemologic Expert Support System for Marine Corps Operational Support). The prototype system was tested a...

  20. Post Disaster Assessment with Decision Support System

    Directory of Open Access Journals (Sweden)

    May Florence J. Franco

    2016-05-01

    Full Text Available The study aimed to develop an online system that would expedite the response of agencies after disaster strikes; generate a list of the kinds and volume of relief aids needed per family affected for a fair, precise and timely distribution; implement community-based ICT by remotely gathering all the necessary data needed for disaster assessment; and adhere to ISO 9126 standards. The system was designed to calculate the effects of disaster in human lives and economy. Integrated into the system were Goggle Maps, Mines and GeoSciences Bureau Hazard Maps, SMS sending features, best passable routes calculations, and decision support on the needs that has to be addressed. The system was made live at pdrrmcguimaras.herokuapp.com to allow remote data entry. The functionality and usability of the system were evaluated by 19 potential users by computing for the arithmetic Mean and Standard Deviation of the survey. The result showed that most of them strongly agreed that the system is acceptable based on these criteria. A group of IT experts also evaluated the system’s conformance to ISO 9126 standards using the same method. The result showed that majority of them strongly agreed that the system conforms to this international standard. The system is seen as a valuable tool for the Provincial Disaster Risk Reduction Management Council (PDRRMC and the National Disaster Risk Reduction Management Council (NDRRMC for it could help expedite the assessment of the effects of disasters and the formulation of response plans and strategies.

  1. Decision support systems: Users, organization and design

    International Nuclear Information System (INIS)

    This paper reviews the features of decision support systems (DSSs), distinguishing them from other kinds of computer-based information systems. The design of an effective DSS requires consideration of not only the user's needs, characteristics and capabilities, but also a knowledge of the situation in which the user functions. It is misleading to consider the user as an individual, isolated from group influences, organisational culture and the larger social environment. The user must actively participate in the design of the DSS which must be tailored for each specific application. The design of the Ispra Risk Management Support System (IRIMS) is summarised as an example of this design philosophy. It was designed in consultation with a group of potential users and is currently being customized for a particular application in collaboration with the Netherlands Ministry for Housing, Physical Planning and the Environment. The lessons learnt from the IRIMS design process are summarised and their implications for the design of systems intended to aid process plant operators are discussed. (author). 15 refs

  2. IGENPRO knowledge-based operator support system

    International Nuclear Information System (INIS)

    Research and development is being performed on the knowledge-based IGENPRO operator support package for plant transient diagnostics and management to provide operator assistance during off-normal plant transient conditions. A generic thermal-hydraulic (T-H) first-principles approach is being implemented using automated reasoning, artificial neural networks and fuzzy logic to produce a generic T-H system-independent/plant-independent package. The IGENPRO package has a modular structure composed of three modules: the transient trend analysis module PROTREN, the process diagnostics module PRODIAG and the process management module PROMANA. Cooperative research and development work has focused on the PRODIAG diagnostic module of the IGENPRO package and the operator training matrix of transients used at the Braidwood Pressurized Water Reactor station. Promising simulator testing results with PRODIAG have been obtained for the Braidwood Chemical and Volume Control System (CVCS), and the Component Cooling Water System. Initial CVCS test results have also been obtained for the PROTREN module. The PROMANA effort also involves the CVCS. Future work will be focused on the long-term, slow and mild degradation transients where diagnoses of incipient T-H component failure prior to forced outage events is required. This will enhance the capability of the IGENPRO system as a predictive maintenance tool for plant staff and operator support

  3. THE RESULTS OF MECHANICAL HEART SUPPORT SYSTEMS «INCOR» IMPLANTATION

    Directory of Open Access Journals (Sweden)

    A. M. Cherniavskiy

    2014-05-01

    Full Text Available The aim of investigation isestimation of mechanical heart support system «INCOR» implantation efficacy. Materials and methods. The Institute of Circulation Pathology has clinical experience of mechanical circulatory support systems «INCOR» (Berlin Heart AG implantation in 12 patients (10 men and 2 women with severe heart failure during the period from November 2006 to October 2012. The main indication for the use of mechanical support of the left ventricle was a left ventricular failure with marked dilatation of the left heart: end-diastolic volume (EDV, LV – 283 ± 58 ml, end-systolic volume (ESV – 233 ± 57 ml, ejection fraction (EF – 16 ± 7%, with preserved function of the right ventricle (RV (RV ejection fraction 35 ± 12%. Results. All patients showed a significant improvement in central hemodynamics in early postoperative period, reducing the volume of the heart chambers: LV EDV from 283 ± 58 to 183 ± 94 ml; LV ESV with 234 ± 57 to 157 ± 65 ml, increased right ventricular ejection fraction (RV EF (from 35 ± 12 to 43 ± 17%. Improve the function of the right ventricle oc- curred mainly due to the expense of left ventricular unloading and pulmonary circulation. In addition, there was a significant improvement in clinical status of patients – regression of symptoms of heart failure, a recovery of the liver and kidney function. Despite the ongoing anticoagulation and antiplatelet therapy under constant parameters of coagulation, there was some complications. Uterine bleeding occurred in 1 patient (16.6%, which required the abolition of anticoagulants and antiplatelet, uterine artery embolization, and as a result has led to thrombosis and stop system «INCOR». Four patients (33.3% had severe thromboembolic complications – acute cerebrovascular accident (CVA. In 1 patient (8% there was a hemorrhagic stroke due to rupture of intracerebral aneurysms with a breakthrough into the lateral ventricle of the brain. In 3 patients (25

  4. Association of physical inactivity with circulatory disease events and hospital treatment costs

    Directory of Open Access Journals (Sweden)

    Davey RC

    2013-04-01

    Full Text Available Rachel C Davey,1 Thomas Cochrane1,21Centre for Research and Action in Public Health, University of Canberra, ACT, Australia; 2Centre for Sport and Exercise Research, Staffordshire University, Stoke on Trent, United KingdomPurpose: Epidemiological studies of chronic disorders need to consider more responsive outcomes, particularly those that manifest themselves across a defined population over a shorter time period, to improve our ability to detect the causes of and intervene in the global epidemics of today. We explore the use of hospital episode statistics as a candidate for this role and estimate the strength of the association of circulatory disease-related events with physical inactivity, considered here as an undesirable health behavior.Settings, patients, and methods: The primary research was set in a mid-sized city in central England. Aggregation was at output area level (comprising ~300 residents; 51 of which were included. A random sample of 761 adults was selected to obtain estimates of the mean level of physical activity within each area. Circulatory disease hospital events were recorded and aggregated by output area over a 2-year period. Hierarchical linear modeling was used to establish the strength of the association between area-level physical activity and circulatory disease events. Sex, age, and reporting quarter were included as additional individual-level explanatory variables.Results: Areas reporting greater activity were less likely (event rate ratio = 0.855; 95% confidence interval [CI]: 0.78–0.94 to have a circulatory disease event, as were females (0.593; 95% CI: 0.47–0.75. Areas with older residents (1.578; 95% CI: 1.5–1.66 and later reporting quarters (1.095; 95% CI: 1.04–1.15 were more likely to report circulatory disease events.Conclusion: This study supports the use of hospital episode statistics as an outcome measure in the epidemiology of circulatory disease and reaffirms the potential importance of

  5. DECISION SUPPORT SYSTEM TO SUPPORT DECISION PROCESSES WITH DATA MINING

    OpenAIRE

    Rok Rupnik; Matjaž Kukar

    2007-01-01

    Traditional techniques of data analysis do not enable the solution of all kind of problems and for that reason they have become insufficient. This caused a newinterdisciplinary field of data mining to arise, encompassing both classical statistical, and modern machine learning techniques to support the data analysis and knowledge discovery from data. Data mining methods are powerful in dealing with large quantities of data, but on the other hand they are difficult to master by business users t...

  6. Ontology Supported Information Systems: A Review

    Directory of Open Access Journals (Sweden)

    Padmavathi, T.

    2014-12-01

    Full Text Available The exponential growth of information on the web far exceeds the capacity of present day information retrieval systems and search engines, making information integration on the web difficult. In order to overcome this, semantic web technologies were proposed by the World Wide Web Consortium (W3C to achieve a higher degree of automation and precision in information retrieval systems. Semantic web, with its promise to deliver machine understanding to the traditional web, has attracted a significant amount of research from academia as well as from industries. Semantic web is an extension of the current web in which data can be shared and reused across the internet. RDF and ontology are two essential components of the semantic web architecture which support a common framework for data storage and representation of data semantics, respectively. Ontologies being the backbone of semantic web applications, it is more relevant to study various approaches in their application, usage, and integration into web services. In this article, an effort has been made to review the research work being undertaken in the area of design and development of ontology supported information systems. This paper also briefly explains the emerging semantic web technologies and standards.

  7. A simplified approach to the regulation of mechanical circulatory support

    Czech Academy of Sciences Publication Activity Database

    Pražák, Josef; Leitermann, D.; Musil, Jan

    2000-01-01

    Roč. 23, č. 8 (2000), s. 569. ISSN 0391-3988. [ESAO congress in co-operation with the ESEM Lausanne /23./.. Lausanne, 31.08.2000-02.09.2000] R&D Projects: GA ČR GA106/98/1373; GA AV ČR KSK1076602 Subject RIV: BO - Biophysics Impact factor: 0.931, year: 2000

  8. Risk factors and outcomes in transfusion-associated circulatory overload

    OpenAIRE

    Murphy, EL; Kwaan, N; Looney, MR; Gajic, O; Hubmayr, RD; Gropper, MA; Koenigsberg, M; Wilson, G.; Matthay, M; Bacchetti, P.; Toy, P

    2013-01-01

    Background: Transfusion-associated circulatory overload is characterized by new respiratory distress and hydrostatic pulmonary edema within 6 hours after blood transfusion, but its risk factors and outcomes are poorly characterized. Methods: Using a case control design, we enrolled 83 patients with severe transfusion-associated circulatory overload identified by active surveillance for hypoxemia and 163 transfused controls at the University of California, San Francisco (UCSF) and Mayo Clinic ...

  9. Reactive Software Agent Anesthesia Decision Support System

    Directory of Open Access Journals (Sweden)

    Grant H. Kruger

    2011-12-01

    Full Text Available Information overload of the anesthesiologist through technological advances have threatened the safety of patients under anesthesia in the operating room (OR. Traditional monitoring and alarm systems provide independent, spatially distributed indices of patient physiological state. This creates the potential to distract caregivers from direct patient care tasks. To address this situation, a novel reactive agent decision support system with graphical human machine interface was developed. The system integrates the disparate data sources available in the operating room, passes the data though a decision matrix comprising a deterministic physiologic rule base established through medical research. Patient care is improved by effecting change to the care environment by displaying risk factors and alerts as an intuitive color coded animation. The system presents a unified, contextually appropriate snapshot of the patient state including current and potential risk factors, and alerts of critical patient events to the operating room team without requiring any user intervention. To validate the efficacy of the system, a retrospective analysis focusing on the hypotension rules were performed. Results show that even with vigilant and highly trained clinicians, deviations from ideal patient care exist and it is here that the proposed system may allow more standardized and improved patient care and potentially outcomes.

  10. The CIHR Circulatory and Respiratory Health Institute

    Directory of Open Access Journals (Sweden)

    Malcolm King

    2000-01-01

    Full Text Available The Canadian Institutes of Health Research (CIHR was officially established on June 7, 2000. Among the 13 institutes that were created, the Institute for Circulatory and Respiratory Health (C&R or CnR, which brings together researchers in the fields of heart, stroke, lung and blood research, has become the principal outlet for respiratory research in this country. Although this large, combined institute was not the first choice of our society or of the respiratory research community at large, we must respect this choice within the context of the new direction for Canadian health research and help to make it work. Over this past summer, the process of recruiting the scientific directors and advisory board members for each CIHR institute has proceeded at a rapid pace. As we go to press, the decisions on the appointment of the 13 inaugural scientific directors are being made. In addition, over the next few weeks, the institute advisory boards will be appointed. The CIHR Governing Council has the ultimate responsibility for these appointments. The Council represents a very broad cross-section of the health research community in Canada; all of us on the Council sincerely wish to see the very best team of directors and board members selected to fulfill these roles.

  11. CT screening of vertebrarterial circulatory disorder

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, Shigeru; Toyoda, Keiko; Moriyama, Hiroshi [Jikei Univ., Tokyo (Japan). School of Medicine

    2001-09-01

    The frequency of MR angiography (MRA) used to diagnose vertebrobasiliar insufficiency appears high. Findings of abnormality by MRA show cases with maldescription of hemivertebral artery. In such cases, it is unclear whether these are due to anaplasia of the vertebral artery or to the existence of morbid constriction, thus requiring confirmation by a vertebral arteriography (VAG). We observe the vascular morphology of vertebral artery by Computed tomography (CT) scanning for screening circulatory disorders. In photography and CT scan reading, the region was severally photographed between foramen magnum and aortic arch by plain CT and contrast CT at a slice of 5 mm. The constrictive region of the vertebral artery was estimated by comparing plain and contrast CT. Subjects were 34 clinical cases of vascular maldescription in the vertebrobasilar artery, nearly no blood vessel description, or blood vessel winding or inclination. We determined the constrictive morbid state of the vertebral or subclavian artery and cervical vertebra deformity. In findings of maldescription by MRA, it was suggested that discrimination is feasible to a certain degree, whether the vertebral artery has a morbid constrictive region or due to anaplasia. Our results suggest that screening by CT scanning may be more efficient than that by MRA. (author)

  12. Simulation software support (S3) system

    International Nuclear Information System (INIS)

    In any significant software development effort the software development environment used is an important element. The size and complexity of modern nuclear power plant training simulators requires a powerful software organization system. This paper discusses the software database and a set of integrated support programs in use on a large number of real-time power plant simulators. Contents, usage and control of the software database, automated development and documentation aides, testing and real time execution environment, integration of trainer features, and expectation of continued modification are explored

  13. Engineering photosynthetic systems for bioregenerative life support

    OpenAIRE

    Masot Mata, Alexandra

    2007-01-01

    Consultable des del TDX Títol obtingut de la portada digitalitzada El projecte MELiSSA (Micro-Ecological Life Support System Alternative) de l'Agència Espacial Europea (ESA) és un ecosistema artificial concebut com una eina per estudiar i desenvolupar la tecnologia per a sistemes de suport de vida biològics requerits per a missions tripulades de llarga durada a l'espai. El fet que el projecte internacional MELiSSA es desenvolupa en cooperació amb organitzacions de diferents països ha pe...

  14. Inherent robust stability of driver support systems

    Institute of Scientific and Technical Information of China (English)

    王龙; J.; Ackermann

    1999-01-01

    Presented are the fact that the transfer function from the front steering angle to yaw rate is strictly positive real, irrespective of the uncertain mass and uncertain velocity, how to determine the positivity margin for this transfer function (some stabilization results are obtained), and how to check the positivity of a controller family. Furthermore,by exploiting the intrinsic structure of system equations and uncertainties, a nonconservative PID stabilization criterion for driver support systems is established. Some interesting results on positivity and connections of PID controllers are shown. Finally, some extreme point results on PID α-stabilization are obtained. These results give certain explanations and justifications for the simulation results performed at German Aerospace Research Center.

  15. Hollow fiber membrane systems for advanced life support systems

    Science.gov (United States)

    Roebelen, G. J., Jr.; Lysaght, M. J.

    1976-01-01

    The practicability of utilizing hollow fiber membranes in vehicular and portable life support system applications is described. A preliminary screening of potential advanced life support applications resulted in the selection of five applications for feasibility study and testing. As a result of the feasibility study and testing, three applications, heat rejection, deaeration, and bacteria filtration, were chosen for breadboard development testing; breadboard hardware was manufactured and tested, and the physical properties of the hollow fiber membrane assemblies are characterized.

  16. Decision support system for structure synthesis of monitoring systems

    OpenAIRE

    Skatkov A. V.; Voronin D. Y.; Danilchuk D. N.

    2008-01-01

    The paper is concerned with a structure synthesis of monitoring systems. In the article a decision support system for such synthesis was proposed and described. In the first phase of the process, the proposed classification of monitoring systems is used. Then adaptive algorithms, simulation and analytic modeling are used. The results of studies carried out by means of the proposed program are represented. The topicality of proposed approach was demonstrated. It should be mentioned, that algor...

  17. Development of severe accident training support system

    International Nuclear Information System (INIS)

    In order for appropriate decision-making during plant operation and management, the professional knowledge, expert's opinion, and previous experiences as well as information for current status are utilized. The operation support systems such as training simulators have been developed to assist these decision-making process, and most of them cover from normal operation to emergency operation because of the very low frequency of severe accident and of uncertaintics included in severe accident phenomena and scenarios. However, the architectures for severe accident management are being established based on severe accident management guidelines in some developed countries. Recentrly, in Korea, as teh severe accident management guideline was developed, the basis for establishing severe accident management architecture is prepared and this leads to the development of tool for systematic education and training for personnel related to severe accident management. The severe accident taining support system thus is developed to assist decision-making during execution of severe accident management guidelines by providing plant status information, prefessional knowledge for phenomena and scenarios, expected behavior for strategy execution, and so on

  18. Internally shielded beam transport and support system

    International Nuclear Information System (INIS)

    Due to environmental concerns, the Advanced Photon Source has a policy that disallows any exposed lead within the facility. This creates a real problem for the beam transport system, not so much for the pipe but for the flexible coupling (bellows) sections. A complete internally shielded x-ray transport system, consisting of long transport lines joined by flexible coupling sections, has been designed for CARS sector 14 to operate either at high vacuum or as a helium flight tube. It can effectively shield against air scattering of wiggler or undulator white beam with proper placement of apertures, collimators, and masks for direct beam control. The system makes use of male- and female-style fittings that create a labyrinth allowing for continuous shielding through the flexible coupling sections. These parts are precision machined from a ternary hypereutectic lead alloy (cast under 15 inches of head pressure to assure a pinhole-free casting) then pressed into either end (rotatable vacuum flanges) of the bellows assembly. The transport pipe itself consists of a four part construction using a stepped transition ring (Z-ring) to connect an inner tube to the vacuum flange and also to a protective and supportive outer tube. The inner tube is wrapped with 1/16 double-prime pure lead sheet to a predetermined thickness following the shape of the stepped transition ring for continuous shielding. This design has been prototyped and radiation tested. copyright 1996 American Institute of Physics

  19. Technological Support for Logistics Transportation Systems

    Science.gov (United States)

    Bujak, Andrzej; Śliwa, Zdzisław; Gębczyńska, Alicja

    The modern world is changing introducing robots, remotely controlled vehicles and other crewless means of transportation to reduce people's mistakes, as the main cause of incidents and crashes during traffic. New technologies are supporting operators and drivers, and according to some studies they can even replace them. Such programs as: AHS, UAH, IVBSS or MTVR are under development to improve traffic flow and its safety, to reduce traffic hazards and crashes. It is necessary to analyze such concepts and implement them boldly, including Polish logistics' companies, new programs, highways' system etc., as they will be applied in the future, so it is necessary to prepare logistics infrastructure ahead of time in order to capitalize on these improvements. The problem is quite urgent as transportation in the country must not be outdated to meet clients' expectations and to keep pace with competing foreign companies.

  20. GIS as spatial decision support system

    Directory of Open Access Journals (Sweden)

    V. Vostrovský

    2011-06-01

    Full Text Available This paper describes the possibility of the Geographic Information Systems (GIS as a means to support decision making in solving spatial problems. Spatial problems accompany every human activity, of which agriculture is no exception. The solutions to these problems requires the application of available knowledge in the relevant decision-making processes. GISs integrate hardware, software, and data for capturing, managing, analyzing, and displaying all forms of geographically referenced information. Coupled with GISs, geography helps to better understand and apply geographic knowledge to a host of global problems (unemployment, environmental pollution, the loss of arable land, epidemics etc.. The result may be a geographical approach represents a new way of thinking and solutions to existing spatial problems. This approach allows to apply existing knowledge to model and analyze these problems and thus help to solve them.

  1. NASA Advanced Explorations Systems: Advancements in Life Support Systems

    Science.gov (United States)

    Shull, Sarah A.; Schneider, Walter F.

    2016-01-01

    The NASA Advanced Exploration Systems (AES) Life Support Systems (LSS) project strives to develop reliable, energy-efficient, and low-mass spacecraft systems to provide environmental control and life support systems (ECLSS) critical to enabling long duration human missions beyond low Earth orbit (LEO). Highly reliable, closed-loop life support systems are among the capabilities required for the longer duration human space exploration missions assessed by NASA's Habitability Architecture Team (HAT). The LSS project is focused on four areas: architecture and systems engineering for life support systems, environmental monitoring, air revitalization, and wastewater processing and water management. Starting with the international space station (ISS) LSS systems as a point of departure (where applicable), the mission of the LSS project is three-fold: 1. Address discrete LSS technology gaps 2. Improve the reliability of LSS systems 3. Advance LSS systems towards integrated testing on the ISS. This paper summarized the work being done in the four areas listed above to meet these objectives. Details will be given on the following focus areas: Systems Engineering and Architecture- With so many complex systems comprising life support in space, it is important to understand the overall system requirements to define life support system architectures for different space mission classes, ensure that all the components integrate well together and verify that testing is as representative of destination environments as possible. Environmental Monitoring- In an enclosed spacecraft that is constantly operating complex machinery for its own basic functionality as well as science experiments and technology demonstrations, it's possible for the environment to become compromised. While current environmental monitors aboard the ISS will alert crew members and mission control if there is an emergency, long-duration environmental monitoring cannot be done in-orbit as current methodologies

  2. Radiation and risk of circulatory diseases in the German uranium miners cohort study

    International Nuclear Information System (INIS)

    ,707) were ever exposed to radiation. Among the exposed, the mean cumulative exposure to radon was 280 W.L.M. (maximum 3,224 W.L.M.), to long-lived radionuclides 4 kBq h/m3 (maximum 132 kBq h/m3) and to external gamma radiation 47 mSv (maximum 909 mSv). No increase in risk of circulatory diseases with increasing cumulative exposure to radon (E.R.R. per 100 W.L.M. = 0,00067; 95% confidence limit (CI): -0,0044 to 0,0058), to external gamma radiation (E.R.R. per Sv -0,18, 95% CI: -0,55 to 0,19) and to long-lived radionuclides (E.R.R per kBq h/m3 -0.0018, 95% CI: - 0.005 to 0.0015) was observed. This was also true for the sub -group of heart diseases and strokes. In addition, no association was found when exposures were categorized and a parameter free model was applied. Conclusion: These results do not support an association between circulatory diseases and exposures to radiation as they typically had occurred among uranium miners. A limitation in interpretation of these data concerns that potential confounder such as smoking, overweight, alcohol, blood pressure and others could not be considered. Literature: Mc Gale, P. and Darby, S.C. Low doses of ionizing Radiation and circulatory diseases: A systematic review of the published epidemiological evidence. Radiat Res 2005; 163: 247-257. (authors)

  3. Radiation and risk of circulatory diseases in the German uranium miners cohort study

    Energy Technology Data Exchange (ETDEWEB)

    Kreuzer, M.; Kreisheimer, M.; Kandel, M.; Tschense, A.; Grosche, B. [Federal Office for Radiation Protection, Neuherberg (Germany)

    2006-07-01

    cohort members (n=50,707) were ever exposed to radiation. Among the exposed, the mean cumulative exposure to radon was 280 W.L.M. (maximum 3,224 W.L.M.), to long-lived radionuclides 4 kBq h/m{sup 3} (maximum 132 kBq h/m3) and to external gamma radiation 47 mSv (maximum 909 mSv). No increase in risk of circulatory diseases with increasing cumulative exposure to radon (E.R.R. per 100 W.L.M. = 0,00067; 95% confidence limit (CI): -0,0044 to 0,0058), to external gamma radiation (E.R.R. per Sv -0,18, 95% CI: -0,55 to 0,19) and to long-lived radionuclides (E.R.R per kBq h/m{sup 3} -0.0018, 95% CI: - 0.005 to 0.0015) was observed. This was also true for the sub -group of heart diseases and strokes. In addition, no association was found when exposures were categorized and a parameter free model was applied. Conclusion: These results do not support an association between circulatory diseases and exposures to radiation as they typically had occurred among uranium miners. A limitation in interpretation of these data concerns that potential confounder such as smoking, overweight, alcohol, blood pressure and others could not be considered. Literature: Mc Gale, P. and Darby, S.C. Low doses of ionizing Radiation and circulatory diseases: A systematic review of the published epidemiological evidence. Radiat Res 2005; 163: 247-257. (authors)

  4. DECISION SUPPORT SYSTEM FOR PRECISION FARMING

    Directory of Open Access Journals (Sweden)

    Harmandeep Singh

    2013-01-01

    Full Text Available A decision support system for precision farming is designed to assist farmers, agricultural experts, research workers or any intellectuals with guidance in making various farming related decisions and help them to access, display and analyze data that have geographic content and meaning. The concept of precision farming is not only related with the use of technologies but it is also about the five R’s that is use of right input (nutrients, water, fertilizer, money, machinery etc., at the right time, at the right place, in the right amount and in the right manner. There is need to have accurate information and suitable decisions regarding the right inputs required for the farming practices and to initiate the step towards the precision farming. DSS calculates irrigation requirement of crops. In this paper, Maps that are shown generated with the help of ArcGIS software (ArcMap tool. The system has been developed using Hypertext Pre Processor (PHP at front end and MySQL at back end.

  5. Koch Process Systems VR-System 350. Technical support document

    International Nuclear Information System (INIS)

    This document presents a conceptual design of a volume reduction system for solid and liquid combustible low-level wastes generated by either PWR or BWR nuclear power plants. The heart of the system is the controlled-air incinerator process which was developed and demonstrated by Los Alamos National Laboratory (Los Alamos) for use in the volume reduction of transuranic (TRU) waste. Equipment descriptions of sub-systems and supporting services are included with sizing basis. Instrument control philosophy is described for the system to be operated unattended. The system configuration, design, and analysis of releases are included to represent a system which is effective, flexible, safe, considers ALARA, and has all the basic needs for ultimate licensing by a utility. 18 references, 13 tables

  6. Peripheral biomarkers of stroke: Focus on circulatory microRNAs.

    Science.gov (United States)

    Vijayan, Murali; Reddy, P Hemachandra

    2016-10-01

    Stroke is the second leading cause of death in the world. Stroke occurs when blood flow stops, and that stoppage results in reduced oxygen supply to neurons in the brain. The occurrence of stroke increases with age, but anyone at any age can suffer from stroke. Recent research has implicated multiple cellular changes in stroke patients, including oxidative stress and mitochondrial dysfunction, inflammatory responses, and changes in mRNA and proteins. Recent research has also revealed that stroke is associated with modifiable and non-modifiable risk factors. Stroke can be controlled by modifiable risk factors, including diet, cardiovascular, hypertension, smoking, diabetes, obesity, metabolic syndrome, depression and traumatic brain injury. Stroke is the major risk factor for vascular dementia (VaD) and Alzheimer's disease (AD). The purpose of this article is to review the latest developments in research efforts directed at identifying 1) latest developments in identifying biomarkers in peripheral and central nervous system tissues, 2) changes in microRNAs (miRNAs) in patients with stroke, 3) miRNA profile and function in animal brain, and 4) protein biomarkers in ischemic stroke. This article also reviews research investigating circulatory miRNAs as peripheral biomarkers of stroke. PMID:27503360

  7. A Support Database System for Integrated System Health Management (ISHM)

    Science.gov (United States)

    Schmalzel, John; Figueroa, Jorge F.; Turowski, Mark; Morris, John

    2007-01-01

    The development, deployment, operation and maintenance of Integrated Systems Health Management (ISHM) applications require the storage and processing of tremendous amounts of low-level data. This data must be shared in a secure and cost-effective manner between developers, and processed within several heterogeneous architectures. Modern database technology allows this data to be organized efficiently, while ensuring the integrity and security of the data. The extensibility and interoperability of the current database technologies also allows for the creation of an associated support database system. A support database system provides additional capabilities by building applications on top of the database structure. These applications can then be used to support the various technologies in an ISHM architecture. This presentation and paper propose a detailed structure and application description for a support database system, called the Health Assessment Database System (HADS). The HADS provides a shared context for organizing and distributing data as well as a definition of the applications that provide the required data-driven support to ISHM. This approach provides another powerful tool for ISHM developers, while also enabling novel functionality. This functionality includes: automated firmware updating and deployment, algorithm development assistance and electronic datasheet generation. The architecture for the HADS has been developed as part of the ISHM toolset at Stennis Space Center for rocket engine testing. A detailed implementation has begun for the Methane Thruster Testbed Project (MTTP) in order to assist in developing health assessment and anomaly detection algorithms for ISHM. The structure of this implementation is shown in Figure 1. The database structure consists of three primary components: the system hierarchy model, the historical data archive and the firmware codebase. The system hierarchy model replicates the physical relationships between

  8. MOIDSS?- Mobile Online Intelligent Decision Support System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — GRID has had a successfully completed Phase I 'Mobile Online Intelligent Decision Support System' (MOIDSS). The system developed into a total solution that supports...

  9. Artificial and bioartificial support systems for liver failure

    DEFF Research Database (Denmark)

    Liu, Jianping; Kjaergard, Lise Lotte; Als-Nielsen, Bodil;

    2002-01-01

    Liver support systems may bridge patients to liver transplantation or recovery from liver failure. This review is to evaluate the beneficial and harmful effects of artificial and bioartificial support systems for acute and acute-on-chronic liver failure....

  10. Support System for Mental Health Professionals

    Directory of Open Access Journals (Sweden)

    Ajit Dandekar

    2015-01-01

    Full Text Available This paper talks of support systems for mental health professionals wherein the Bombay Psychiatric Society (BPS should devote some meetings exclusively to problems pertaining to the profession, e.g., long and odd working hours leading to potentially hazardous practice schedules, unhealthy competitive attitudes and culture. A crash course in self-defence against potentially psychotic patients and drug addicts is advocated as also awareness of the potential hazards in dealing with the litigious paranoid patients, erotomaniacs and some of the difficult hysterical patients. Potential medicolegal problems arise in treating an uncooperative patient without his knowledge and consent on an outpatient department basis, admitting such an uncooperative patient to a nursing home or a hospital, administering electroconvulsive therapies, maintaining detailed clinical records of patients, and legal issues involving smaller psychiatric private nursing homes. This paper stresses on the use of Yoga as a recognised psycho-physiological therapy. Furthermore, it suggests on the need for BPS, as a professional body, to have a cell to guide and help aspiring young professionals in setting up private practice. It points out the need to evolve some concrete programmes that in the long run should help alleviate stresses and strains and promote positive comprehensive health amongst mental health professionals.

  11. Control system upgrades support better plant economics

    International Nuclear Information System (INIS)

    This paper (second in the series, see [1]) provides insight on how nuclear plants can achieve better efficiencies and reduced operations and maintenance (O and M) costs through focused control system upgrades. An understanding of this relationship is necessary to properly assess the economics of plant refurbishment decisions. Traditional economic feasibility assessment methods such as benefit cost analysis (BCA), internal rate of return (IRR), benefit cost ratios (B/C), or payback analysis are often performed without full consideration of project alternatives, quantified benefits, and life cycle costing. Consideration must be given to not only capital cost and project risk, but also to the potential economic benefits of new technology and added functionality offered by plant upgrades. Recent experience shows that if upgrades are focused on priority objectives, and are effectively implemented, they can deliver significant payback over the life of the plant, sometimes orders of magnitude higher than their initial capital cost. The following discussion explores some of the key issues and rationale behind upgrade decisions and their impact on improved plant efficiency and reduced O and M costs. A subsequent paper will explain how the justification for these improvements can be captured in an economic analysis and feasibility study to support strategic decision-making in a plant refurbishment context. (author)

  12. A Computuerized Operator Support System Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Ken Thomas; Ronald Boring; Roger Lew; Tom Ulrich; Richard Villim

    2013-08-01

    A report was published by the Idaho National Laboratory in September of 2012, entitled Design to Achieve Fault Tolerance and Resilience, which described the benefits of automating operator actions for transients. The report identified situations in which providing additional automation in lieu of operator actions would be advantageous. It recognized that managing certain plant upsets is sometimes limited by the operator’s ability to quickly diagnose the fault and to take the needed actions in the time available. Undoubtedly, technology is underutilized in the nuclear power industry for operator assistance during plant faults and operating transients. In contrast, other industry sectors have amply demonstrated that various forms of operator advisory systems can enhance operator performance while maintaining the role and responsibility of the operator as the independent and ultimate decision-maker. A computerized operator support system (COSS) is proposed for use in nuclear power plants to assist control room operators in addressing time-critical plant upsets. A COSS is a collection of technologies to assist operators in monitoring overall plant performance and making timely, informed decisions on appropriate control actions for the projected plant condition. The COSS does not supplant the role of the operator, but rather provides rapid assessments, computations, and recommendations to reduce workload and augment operator judgment and decision-making during fast-moving, complex events. This project proposes a general model for a control room COSS that addresses a sequence of general tasks required to manage any plant upset: detection, validation, diagnosis, recommendation, monitoring, and recovery. The model serves as a framework for assembling a set of technologies that can be interrelated to assist with each of these tasks. A prototype COSS has been developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based

  13. A Computuerized Operator Support System Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Ken Thomas; Ronald Boring; Roger Lew; Tom Ulrich; Richard Villim

    2013-11-01

    A report was published by the Idaho National Laboratory in September of 2012, entitled Design to Achieve Fault Tolerance and Resilience, which described the benefits of automating operator actions for transients. The report identified situations in which providing additional automation in lieu of operator actions would be advantageous. It recognized that managing certain plant upsets is sometimes limited by the operator’s ability to quickly diagnose the fault and to take the needed actions in the time available. Undoubtedly, technology is underutilized in the nuclear power industry for operator assistance during plant faults and operating transients. In contrast, other industry sectors have amply demonstrated that various forms of operator advisory systems can enhance operator performance while maintaining the role and responsibility of the operator as the independent and ultimate decision-maker. A computerized operator support system (COSS) is proposed for use in nuclear power plants to assist control room operators in addressing time-critical plant upsets. A COSS is a collection of technologies to assist operators in monitoring overall plant performance and making timely, informed decisions on appropriate control actions for the projected plant condition. The COSS does not supplant the role of the operator, but rather provides rapid assessments, computations, and recommendations to reduce workload and augment operator judgment and decision-making during fast-moving, complex events. This project proposes a general model for a control room COSS that addresses a sequence of general tasks required to manage any plant upset: detection, validation, diagnosis, recommendation, monitoring, and recovery. The model serves as a framework for assembling a set of technologies that can be interrelated to assist with each of these tasks. A prototype COSS has been developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based

  14. Environmental Control and Life Support System, Water Recovery System

    Science.gov (United States)

    2000-01-01

    The Environmental Control and Life Support System (ECLSS) Group of the Flight Projects Directorate at the Marshall Space Flight Center (MSFC) is responsible for designing and building the life support systems that will provide the crew of the International Space Station (ISS) a comfortable environment in which to live and work. This is a close-up view of ECLSS Water Recovery System (WRS) racks. The MSFC's ECLSS Group overseas much of the development of the hardware that will allow a constant supply of clean water for four to six crewmembers aboard the ISS. The WRS provides clean water through the reclamation of wastewaters, including water obtained from the Space Shuttle's fuel cells, crewmember urine, used shower, handwash and oral hygiene water cabin humidity condensate, and Extravehicular Activity (EVA) wastes. The WRS is comprised of a Urine Processor Assembly (UPA), and a Water Processor Assembly (WPA). The UPA accepts and processes pretreated crewmember urine to allow it to be processed along with other wastewaters in the WPA, which removes free gas, organic, and nonorganic constituents before the water goes through a series of multifiltration beds for further purification. Product water quality is monitored primarily through conductivity measurements. Unacceptable water is sent back through the WPA for reprocessing. Clean water is sent to a storage tank. The water must meet stringent purity standards before consumption by the crew. The UPA provided by the MSFC and the WRA is provided by the prime contractor, Hamilton Sundstrand Space Systems, International (HSSSI) from Cornecticut.

  15. Using systems thinking to support clinical system transformation.

    Science.gov (United States)

    Best, Allan; Berland, Alex; Herbert, Carol; Bitz, Jennifer; van Dijk, Marlies W; Krause, Christina; Cochrane, Douglas; Noel, Kevin; Marsden, Julian; McKeown, Shari; Millar, John

    2016-05-16

    Purpose - The British Columbia Ministry of Health's Clinical Care Management initiative was used as a case study to better understand large-scale change (LSC) within BC's health system. Using a complex system framework, the purpose of this paper is to examine mechanisms that enable and constrain the implementation of clinical guidelines across various clinical settings. Design/methodology/approach - Researchers applied a general model of complex adaptive systems plus two specific conceptual frameworks (realist evaluation and system dynamics mapping) to define and study enablers and constraints. Focus group sessions and interviews with clinicians, executives, managers and board members were validated through an online survey. Findings - The functional themes for managing large-scale clinical change included: creating a context to prepare clinicians for health system transformation initiatives; promoting shared clinical leadership; strengthening knowledge management, strategic communications and opportunities for networking; and clearing pathways through the complexity of a multilevel, dynamic system. Research limitations/implications - The action research methodology was designed to guide continuing improvement of implementation. A sample of initiatives was selected; it was not intended to compare and contrast facilitators and barriers across all initiatives and regions. Similarly, evaluating the results or process of guideline implementation was outside the scope; the methods were designed to enable conversations at multiple levels - policy, management and practice - about how to improve implementation. The study is best seen as a case study of LSC, offering a possible model for replication by others and a tool to shape further dialogue. Practical implications - Recommended action-oriented strategies included engaging local champions; supporting local adaptation for implementation of clinical guidelines; strengthening local teams to guide implementation; reducing

  16. Prototyping a Rangeland Decision Support System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal is submitted under the Innovative Tools and Techniques Supporting the Practical Uses of Earth Science Observations topic. We seek to create a...

  17. A Geospatial Decision Support System Toolkit Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to design a working prototype Geospatial Decision Support Toolkit (GeoKit) that will enable scientists, agencies, and stakeholders to configure and...

  18. Electrical Properties of Carbon Fiber Support Systems

    OpenAIRE

    W. Cooper; Daly, C; Demarteau, M.; Fast, J.(Pacific Northwest National Laboratory, Richland, Washington, 99352, U.S.A.); K. Hanagaki; Johnson, M.; Kuykendall, W.; Lubatti, H.; Matulik, M; Nomerotski, A.; B. Quinn; Wang, J.

    2005-01-01

    Carbon fiber support structures have become common elements of detector designs for high energy physics experiments. Carbon fiber has many mechanical advantages but it is also characterized by high conductivity, particularly at high frequency, with associated design issues. This paper discusses the elements required for sound electrical performance of silicon detectors employing carbon fiber support elements. Tests on carbon fiber structures are presented indicating that carbon fiber must be ...

  19. Visitor schedule management system- an intelligent decision support system

    CERN Document Server

    Nidhra, Srinivas; Ethiraj, Vinay Sudha

    2012-01-01

    Travelling salesman problem is a problem which is of high interest for researchers, industry professionals, and academicians. Visitor or salesman used to face lot of problems with respect to scheduling based on meeting top ranked clients. Even excel sheet made the work tedious. So these flaws propelled us to design an intelligent decision support system. This paper reports the problem definition we tried to address and possible solution to this problem. We even explained the project design and implementation of our visitor schedule management system.. Our system made a major contribution in terms of valuable resources such as time and satisfying high ranked clients efficiently. We used optimization via mathematical programming to solve these issues.

  20. Space Launch System Vibration Analysis Support

    Science.gov (United States)

    Johnson, Katie

    2016-01-01

    The ultimate goal for my efforts during this internship was to help prepare for the Space Launch System (SLS) integrated modal test (IMT) with Rodney Rocha. In 2018, the Structural Engineering Loads and Dynamics Team will have 10 days to perform the IMT on the SLS Integrated Launch Vehicle. After that 10 day period, we will have about two months to analyze the test data and determine whether the integrated vehicle modes/frequencies are adequate for launching the vehicle. Because of the time constraints, NASA must have newly developed post-test analysis methods proven well and with technical confidence before testing. NASA civil servants along with help from rotational interns are working with novel techniques developed and applied external to Johnson Space Center (JSC) to uncover issues in applying this technique to much larger scales than ever before. We intend to use modal decoupling methods to separate the entangled vibrations coming from the SLS and its support structure during the IMT. This new approach is still under development. The primary goal of my internship was to learn the basics of structural dynamics and physical vibrations. I was able to accomplish this by working on two experimental test set ups, the Simple Beam and TAURUS-T, and by doing some light analytical and post-processing work. Within the Simple Beam project, my role involves changing the data acquisition system, reconfiguration of the test set up, transducer calibration, data collection, data file recovery, and post-processing analysis. Within the TAURUS-T project, my duties included cataloging and removing the 30+ triaxial accelerometers, coordinating the removal of the structure from the current rolling cart to a sturdy billet for further testing, preparing the accelerometers for remounting, accurately calibrating, mounting, and mapping of all accelerometer channels, and some testing. Hammer and shaker tests will be performed to easily visualize mode shapes at low frequencies. Short

  1. Sttudy on intelligent spatial decision support system of agriculture

    Institute of Scientific and Technical Information of China (English)

    ZHANG Rong-mei; SUN Jie-li

    2006-01-01

    This paper studies how to apply GIS, ES, and Data mining and WEB technologies in agriculture Decision Support System, with the researching background of Hebei expert system for farming soil variable rate fertilization. A model of agriculture intelligent spatial decision support system is built and the key technologies to implement this system are described in details.

  2. Decision support telemedicine systems: A conceptual model and reusable templates

    NARCIS (Netherlands)

    B. Nannings; A. Abu-Hanna

    2006-01-01

    Decision support telemedicine systems (DSTSs) are systems combining elements from telemedicine and clinical decision support systems. Although emerging more, these types of systems have not been given much attention in the literature. Our objective is to define the term DSTS, to propose a general DS

  3. Organ donation after circulatory death: the forgotten donor?

    Science.gov (United States)

    Rady, Mohamed Y; Verheijde, Joseph L; McGregor, Joan

    2006-01-01

    Donation after circulatory death (DCD) can be performed on neurologically intact donors who do not fulfill neurologic or brain death criteria before circulatory arrest. This commentary focuses on the most controversial donor-related issues anticipated from mandatory implementation of DCD for imminent or cardiac death in hospitals across the USA. We conducted a nonstructured review of selected publications and websites for data extraction and synthesis. The recommended 5 min of circulatory arrest does not universally fulfill the dead donor rule when applied to otherwise neurologically intact donors. Scientific evidence from extracorporeal perfusion in circulatory arrest suggests that the procurement process itself can be the event causing irreversibility in DCD. Legislative abandonment of the dead donor rule to permit the recovery of transplantable organs is necessary in the absence of an adequate scientific foundation for DCD practice. The designation of organ procurement organizations or affiliates to obtain organ donation consent introduces self-serving bias and conflicts of interest that interfere with true informed consent. It is important that donors and their families are not denied a 'good death', and the impact of DCD on quality of end-of-life care has not been satisfactorily addressed to achieve this. PMID:17020597

  4. Analysis of a Ubiquitous Performance Support System for Teachers

    Science.gov (United States)

    Chen, Chao-Hsiu; Hwang, Gwo-Jen; Yang, Tzu-Chi; Chen, Shih-Hsuan; Huang, Shen-Yu

    2009-01-01

    This paper describes a Ubiquitous Performance Support System for Teachers (UPSST) and its implementation model. Personal Digital Assistants (PDAs) were used as the platform to support high-school teachers. Based on concepts of Electronic Performance Support Systems and design-based research, the authors conducted an iterative process of analysis,…

  5. A systematic requirements engineering approach for decision support systems

    OpenAIRE

    Garcia Martinez, Stephany

    2014-01-01

    Decision Support Systems have emerged as a dominant technology capable to integrate heterogeneous sources into an analytical fashion to facilitate and provide a better decision-making process. Successful projects of Decision Support Systems implementation have confirmed a highlevel of user satisfaction and return on investment. Despite the potential of these systems, several surveys have indicated that the failure rate of Decision Support System projects in case studies and literature is cons...

  6. Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine

    OpenAIRE

    Cecconi, Maurizio; De Backer, Daniel; Antonelli, Massimo; Beale, Richard; Bakker, Jan; Hofer, Christoph; Jaeschke, Roman; Mebazaa, Alexandre; Pinsky, Michael R; Teboul, Jean Louis; Vincent, Jean Louis; Rhodes, Andrew

    2014-01-01

    Objective Circulatory shock is a life-threatening syndrome resulting in multiorgan failure and a high mortality rate. The aim of this consensus is to provide support to the bedside clinician regarding the diagnosis, management and monitoring of shock. Methods The European Society of Intensive Care Medicine invited 12 experts to form a Task Force to update a previous consensus (Antonelli et al.: Intensive Care Med 33:575–590, 2007). The same five questions addressed in the earlier consensus we...

  7. Experimental Approach to Effect Estimation of Decision Support Systems

    International Nuclear Information System (INIS)

    Recently human error has been introduced as one of the serious causes of accidents in safety critical systems such as nuclear power plants (NPPs). In order to prevent human errors, many efforts have been made to improve main control room (MCR) interface designs and to develop decision support systems that allow convenient MCR operation and maintenance. For the advanced MCRs, various types of decision support systems have been developed, such as intelligent advisors, alarm systems, computer-based procedures, fault diagnostic systems and computerized decision support systems. It is very important to design highly reliable decision support systems in order to adapt them in actual NPPs. In addition, to evaluate those support systems and validate their efficiency and reliability is as important as to design highly reliable decision support systems, because inappropriate decision support systems or automation systems can cause adverse effects. Research to experimentally estimate a decision support system's impact on the operator's performance has been previously reported in the literature. In most experimental studies, operator performance with decision support systems such as information aid systems is estimated by the quality and accuracy of a diagnostic performance as well as by other various subjective or objective measurements. Subjective methods such as the NASA-Task Load Index (NASATLX) and modified Cooper-Harper (MCH) have been employed to measure the subject's mental workload. In this work, target decision support systems are selected and evaluated by experiments. The target systems are an alarm system, a fault diagnosis system, a computerized procedure system, and an operation validation system. For the experimental evaluation, a prototype was implemented based on a micro-simulator

  8. THE PECULIARITIES OF TEACHER'S SUPPORT OF PUPILS IN PRISON SYSTEM

    OpenAIRE

    Lavrina, R.

    2010-01-01

    This article discusses the peculiarities of pedagogical support, directed on the development of positive social identity of pupils in prison system. The pedagogical support of students is gradually considered in the context of humanization.

  9. Vibrational characteristics of fluid filled gap support systems

    International Nuclear Information System (INIS)

    A fluid filled gap support system is a hydrodynamic support system, which is composed of an inner cylinder and an outer restraint cylinder surrounding the inner cylinder, with a small gap between them filled with fluid. In pool type LMFBRs, the fluid filled gap support system is considered to be efficient as a seismic support system for internal components, such as pumps, IHXs etc., which are suspended from the deck. Because this support system has no mechanical connections with internal components, and accommodates the thermal deformation without causing thermal stress. This support system fundamentally has a two concentric cylindrical geometry separated by an annular fluid region. In this study, a device using seal rings was designed to suppress the axial flows described above. Analyses were performed to evaluate vibrational characteristics for the system, such as added mass and damping factors. Also, vibration tests were performed to examine the validity of the analytical method. (orig./GL)

  10. Computer support for mechatronic control system design

    NARCIS (Netherlands)

    Amerongen, van Job; Coelingh, Erik; Vries, de Theo J.A.

    2000-01-01

    This paper discusses the demands for proper tools for computer aided control system design of mechatronic systems and identifies a number of tasks in this design process. Real mechatronic design, involving input from specialists from varying disciplines, requires that the system can be represented i

  11. Donation after cardio-circulatory death liver transplantation

    Institute of Scientific and Technical Information of China (English)

    Hieu Le Dinh; Arnaud de Roover; Abdour Kaba; Séverine Lauwick; Jean Joris; Jean Delwaide; Pierre Honoré

    2012-01-01

    The renewed interest in donation after cardio-circulatory death (DCD) started in the 1990s following the limited success of the transplant community to expand the donation after brain-death (DBD) organ supply and following the request of potential DCD families.Since then,DCD organ procurement and transplantation activities have rapidly expanded,particularly for nonvital organs,like kidneys.In liver transplantation (LT),DCD donors are a valuable organ source that helps to decrease the mortality rate on the waiting lists and to increase the availability of organs for transplantation despite a higher risk of early graft dysfunction,more frequent vascular and ischemia-type biliary lesions,higher rates of re-listing and re-transplantation and lower graft survival,which are obviously due to the inevitable warm ischemia occurring during the declaration of death and organ retrieval process.Experimental strategies intervening in both donors and recipients at different phases of the transplantation process have focused on the attenuation of ischemia-reperfusion injury and already gained encouraging results,and some of them have found their way from pre-clinical success into clinical reality.The future of DCD-LT is promising.Concerted efforts should concentrate on the identification of suitable donors (probably Maastricht category Ⅲ DCD donors),better donor and recipient matching (high risk donors to low risk recipients),use of advanced organ preservation techniques (oxygenated hypothermic machine perfusion,normothermic machine perfusion,venous systemic oxygen persufflation),and pharmacological modulation (probably a multi-factorial biologic modulation strategy) so that DCD liver allografts could be safely utilized and attain equivalent results as DBD-LT.

  12. A support systems perspective on risk-based regulation

    International Nuclear Information System (INIS)

    A link is established between the concept of time varying risk and support system contributions to risk. The impact of support system design and performance on nuclear plant safety was examined in a series of projects for the Electric Power Research Institute (EPRI). This paper gives the findings and recommendations of those studies. Results of investigations by others of time dependent risk show that the periods of high risk are periods of low support system availability. Together these results show that support systems can be significant to plant safety, that the impact is highly plant specific, and that controlling the availability of support systems has a high potential for improving risk. These results validate a risk-based approach to regulation that addresses the plant-specific and time-dependent character of support system issues

  13. Information support of social protection system

    OpenAIRE

    Kuznetsova, Elena

    2007-01-01

    The article is about the features and problems of informational ensuring of the social protection system in Russia. The author analyzes the current practice of informational ensuring system of social protection, pointing out the flaws. The author proposes possible variants solutions to problems.

  14. Maintenance support system using portable information device and its evaluation

    International Nuclear Information System (INIS)

    The purpose of the present study is to develop an integrated maintenance support system, which has the functions supporting maintenance personnel in the field. The prototype system has been developed to demonstrate feasibility of the proposed framework. The focus had been set on the usability evaluation to examine interface usability and to verify the usefulness of the supportive functions. Through the scenario based evaluation and the questionnaire survey, the effectiveness and the usability of the proposed system has been confirmed. (author)

  15. Research on Development of Corn Production Decision Support System

    OpenAIRE

    Nan Lin; Dongming Li; Chunguang Bi

    2013-01-01

    This research was about the application of decision support system in agriculture. The subject of study was the corn cultivated in Jilin province, northeast of China. The research synthesized expertise and experience on corn cultivation, plant protection, soil and fertilizer, and synthesized agriculture ecology from experts, integrating computer technology, principle of decision support system with corn production knowledge. The research also concerned decision support system for corn fertili...

  16. Crop Production for Advanced Life Support Systems

    OpenAIRE

    Wheeler, R M; Sager, J C

    2006-01-01

    The use of plants for bioregenerative life support for space missions was first studied by the US Air Force in the 1950s and 1960s. Extensive testing was also conducted from the 1960s through the 1980s by Russian researchers located at the Institute of Biophysics in Krasnoyarsk, Siberia, and the Institute for Biomedical Problems in Moscow. NASA initiated bioregenerative research in the 1960s (e.g., Hydrogenomonas) but this research did not include testing with plants until about 1980, with th...

  17. Information systems support for OR product standardization.

    Science.gov (United States)

    Faetanini, C

    1994-02-01

    A critical reason why many healthcare institutions cannot effectively standardize OR products is that they cannot access necessary information. An OR information system that manages, tracks and generates documentation on OR inventory is an important answer to implementing change. At least four key areas any information system should address in order to make standardization a reality are 1) clinical preference, 2) supplying a changing case mix, 3) product usage data and 4) vendor performance. OR information systems operate on various hardware platforms. Users have more software choices than ever before, because connectivity issues have been effectively solved through the development of standard electronic transaction sets. PMID:10131895

  18. A cholinergic contribution to the circulatory responses evoked at the onset of handgrip exercise in humans

    DEFF Research Database (Denmark)

    Vianna, Lauro C; Fadel, Paul J; Secher, Niels H; Fisher, James P

    2015-01-01

    A cholinergic (muscarinic) contribution to the initial circulatory response to exercise in humans remains controversial. Herein, we posit that this may be due to exercise mode with a cholinergic contribution being important during isometric handgrip exercise, where the hyperemic response of the...... muscle is relatively small compared with the onset of leg cycling, where a marked increase in muscle blood flow rapidly occurs as a consequence of multiple redundant mechanisms. We recorded blood pressure (BP; brachial artery), stroke volume (pulse contour analysis), cardiac output, and systemic vascular...

  19. Control Systems Cyber Security Standards Support Activities

    Energy Technology Data Exchange (ETDEWEB)

    Robert Evans

    2009-01-01

    The Department of Homeland Security’s Control Systems Security Program (CSSP) is working with industry to secure critical infrastructure sectors from cyber intrusions that could compromise control systems. This document describes CSSP’s current activities with industry organizations in developing cyber security standards for control systems. In addition, it summarizes the standards work being conducted by organizations within the sector and provides a brief listing of sector meetings and conferences that might be of interest for each sector. Control systems cyber security standards are part of a rapidly changing environment. The participation of CSSP in the development effort for these standards has provided consistency in the technical content of the standards while ensuring that information developed by CSSP is included.

  20. E3 Travel & Mission Support System

    Data.gov (United States)

    US Agency for International Development — ETRAMS is a travel data collection system developed by the CKM team in E3 that collects information on both the basic details of an employee's trips (destination,...

  1. Quality education as quality system support

    International Nuclear Information System (INIS)

    Within the last ten years we are witnesses of the political and economical system transformation, that imposed the need for changing the way of thinking and work planning. The quality has become the imperative of working and a precondition for survival in the market. Solving the quality problems seeks planned and systematic approach that supposed appropriate personnel with adequate knowledge in the field of quality management and implementation of the quality system. Having in mind the need for documented quality system and quality management OKTA, has already started with personnel educational process for quality as a precondition for successful establishment of quality system. In this paper we present quality education approach and manner of its realization in OKTA Crude Oil Refinery - Skopje, Macedonia. (Original)

  2. Post Disaster Assessment with Decision Support System

    OpenAIRE

    May Florence J. Franco

    2016-01-01

    The study aimed to develop an online system that would expedite the response of agencies after disaster strikes; generate a list of the kinds and volume of relief aids needed per family affected for a fair, precise and timely distribution; implement community-based ICT by remotely gathering all the necessary data needed for disaster assessment; and adhere to ISO 9126 standards. The system was designed to calculate the effects of disaster in human lives and economy. Integrated into...

  3. Support for Quality Assurance in End-User Systems.

    Science.gov (United States)

    Klepper, Robert; McKenna, Edward G.

    1989-01-01

    Suggests an approach that organizations can take to provide centralized support services for quality assurance in end-user information systems, based on the experiences of a support group at Citicorp Mortgage, Inc. The functions of the support group include user education, software selection, and assistance in testing, implementation, and support…

  4. Using Collaborative Authoring To Develop a Hypermedia Performance Support System.

    Science.gov (United States)

    Tjahjono, Benny; Greenough, Richard

    2002-01-01

    Considers the need of factory workers for support in rapidly changing tasks and suggests that electronic performance support systems can reduce training time, can be updated many times as procedures change, and can allow those with relevant manufacturing expertise to create electronic procedures that support shop floor workers more effectively.…

  5. System Support for Managing Invalid Bindings

    CERN Document Server

    Das, Lachhman; Shah, Azhar; Khoumbati, Khalil; 10.5121/iju.2011.2303

    2011-01-01

    Context-aware adaptation is a central aspect of pervasive computing applications, enabling them to adapt and perform tasks based on contextual information. One of the aspects of context-aware adaptation is reconfiguration in which bindings are created between application component and remote services in order to realize new behaviour in response to contextual information. Various research efforts provide reconfiguration support and allow the development of adaptive context-aware applications from high-level specifications, but don't consider failure conditions that might arise during execution of such applications, making bindings between application and remote services invalid. To this end, we propose and implement our design approach to reconfiguration to manage invalid bindings. The development and modification of adaptive context-aware applications is a complex task, and an issue of an invalidity of bindings further complicates development efforts. To reduce the development efforts, our approach provides ...

  6. A system for graphology analysis support

    OpenAIRE

    Grah, Danijel

    2012-01-01

    In the diploma thesis we focused on the development of the system that belongs to software solutions in the field of graphology. In cooperation with an expert in the field of graphology we created a user friendly system that enables managing and saving the measurements. The Machine learning methods were tested on the data that we had at disposal. We decided to include the kNN method. A simple interface for entering any number of decision rules was also implemented. With the help of the expert...

  7. Supporting Continuous Improvement in California's Education System

    Science.gov (United States)

    Darling-Hammond, Linda; Plank, David N.

    2015-01-01

    California's new accountability system originated in the radical decentralization of power and authority from Sacramento to local schools and their communities brought about by the Legislature's adoption of the Local Control Funding Formula (LCFF) in 2013. Under California's previous accountability policies and the federal "No Child Left…

  8. Air Systems Provide Life Support to Miners

    Science.gov (United States)

    2014-01-01

    Through a Space Act Agreement with Johnson Space Center, Paragon Space Development Corporation, of Tucson, Arizona, developed the Commercial Crew Transport-Air Revitalization System, designed to provide clean air for crewmembers on short-duration space flights. The technology is now being used to help save miners' lives in the event of an underground disaster.

  9. Controlled ecological life-support system - Use of plants for human life-support in space

    Science.gov (United States)

    Chamberland, D.; Knott, W. M.; Sager, J. C.; Wheeler, R.

    1992-01-01

    Scientists and engineers within NASA are conducting research which will lead to development of advanced life-support systems that utilize higher plants in a unique approach to solving long-term life-support problems in space. This biological solution to life-support, Controlled Ecological Life-Support System (CELSS), is a complex, extensively controlled, bioengineered system that relies on plants to provide the principal elements from gas exchange and food production to potable water reclamation. Research at John F. Kennedy Space Center (KSC) is proceeding with a comprehensive investigation of the individual parts of the CELSS system at a one-person scale in an approach called the Breadboard Project. Concurrently a relatively new NASA sponsored research effort is investigating plant growth and metabolism in microgravity, innovative hydroponic nutrient delivery systems, and use of highly efficient light emitting diodes for artificial plant illumination.

  10. Informal Online Decision Making: Current Practices and Support System Design

    OpenAIRE

    André, Paul; Drucker, Steven; schraefel, m.c.

    2007-01-01

    Existing group decision support systems are too complex to support lightweight, informal decision making made popular by the amount of information available on the Web. From an examination of related work, an online survey and a formative study to examine how people currently use the Web for decision support, we present a set of design recommendations towards the development of an informal Web decision support tool.

  11. Review of Operation and Maintenance Support Systems for Research Reactors

    International Nuclear Information System (INIS)

    Operation support systems do not directly control the plant but it can aid decision making itself by obtaining and analyzing large amounts of data. Recently, the demand of research reactor is growing and the need for operation support systems is increasing, but it has not been applied for research reactors. This study analyzes operation and maintenance support systems of NPPs and suggests appropriate systems for research reactors based on analysis. In this paper, operation support systems for research reactors are suggested by comparing with those of power reactors. Currently, research reactors do not cover special systems in order to improve safety and operability in comparison with power reactors. Therefore we expect to improve worth to use by introducing appropriate systems for research reactors. In further research, we will develop an appropriate system such as applications or tools that can be applied to the research reactor

  12. Japanese Learning Support Systems: Hinoki Project Report

    Directory of Open Access Journals (Sweden)

    Bor HODOŠČEK

    2012-12-01

    Full Text Available In this report, we introduce the Hinoki project, which set out to develop web-based Computer-Assisted Language Learning (CALL systems for Japanese language learners more than a decade ago. Utilizing Natural Language Processing technologies and other linguistic resources, the project has come to encompass three systems, two corpora and many other resources. Beginning with the reading assistance system Asunaro, we describe the construction of Asunaro's multilingual dictionary and it's dependency grammar-based approach to reading assistance. The second system, Natsume, is a writing assistance system that uses large-scale corpora to provide an easy to use collocation search feature that is interesting for it's inclusion of the concept of genre. The final system, Nutmeg, is an extension of Natsume and the Natane learner corpus. It provides automatic correction of learners errors in compositions by using Natsume for its large corpus and genre-aware collocation data and Natane for its data on learner errors.-----V poročilu predstavljamo projekt Hinoki, ki je bil zastavljen pred več kot desetimi leti za izdelavo spletnih sistemov za računalniško podprto učenje japonščine kot tujega jezika. Z uporabo jezikovnih tehnologij in drugih jezikovnih virov so bili v okviru projekta razviti trije sistemi, dva korpusa in veliko drugih virov. V nadaljevanju predstavljamo sistem Asunaro za podporo branju, izgradnjo njegovega večjezičnega slovarja in pristop k podpori branju, ki sloni na odvisnostni slovnici; sistem za podporo pisanju Natsume s preprostim vmesnikom za iskanje žanrsko določenih kolokacij v obsežnih korpusih; ter sistem Nutmeg za samodejno popravljanje napak. Nutmeg je nadgradnja sistema Natsume in učnega korpusa Natane, ponuja samodejno popravljanje napak med samim pisanjem z uporabo žanrsko določenih kolokacijskih informacij iz obsežnih korpusov preko sistema Natsume in informacij o napakah piscev, ki se učijo japonščine kot tujega

  13. [Moving Mirror Scanning System Based on the Flexible Hinge Support].

    Science.gov (United States)

    Xie, Fei; Feng, Fei; Wang, Fu-bei; Wu, Qiong-shui; Zeng, Li-bo

    2015-08-01

    In order to improve moving mirror drive of Fourier transform infrared spectrometer, we design a dynamic scanning system based on flexible hinge support. Using the flexible hinge support way and the voice coil motor drive mode. Specifically, Using right Angle with high accuracy high stability type flexible hinge support mechanism support moving mirror, dynamic mirror can be moved forward and backward driven by voice coil motor reciprocating motion, DSP control system to control the moving mirror at a constant speed. The experimental results show that the designed of moving mirror scanning system has advantages of stability direction, speed stability, superior seismic performance. PMID:26672322

  14. Licensing Support Network: An Electronic Discovery System

    International Nuclear Information System (INIS)

    The necessary authorization for the U. S. Department of Energy's (DOE) Office of Civilian Radioactive Waste Management (OCRWM) to submit a License Application (LA) is contingent upon the policy process defined in the Nuclear Waste Policy Act, as amended (NWPA), with some steps yet to occur. In spite of this uncertainty, the DOE must take prudent and appropriate action now, and over the next several years, to prepare for submittal of an application and to facilitate the U. S. Nuclear Regulatory Commission (NRC) review of this application, if the Yucca Mountain site is recommended and approved for repository development. One of these steps the DOE has taken involves working with the NRC's Advisory Review Panel to develop Licensing Support Network (LSN) requirements and guidelines. The NRC has made a prototype of the LSN web page available at www.LSNNET.gov. The OCRWM part of the LSN currently has an indefinite life cycle and may need to remain in existence until the repository is closed, which could be as long as 325 years

  15. Reliability Growth in Space Life Support Systems

    Science.gov (United States)

    Jones, Harry W.

    2014-01-01

    A hardware system's failure rate often increases over time due to wear and aging, but not always. Some systems instead show reliability growth, a decreasing failure rate with time, due to effective failure analysis and remedial hardware upgrades. Reliability grows when failure causes are removed by improved design. A mathematical reliability growth model allows the reliability growth rate to be computed from the failure data. The space shuttle was extensively maintained, refurbished, and upgraded after each flight and it experienced significant reliability growth during its operational life. In contrast, the International Space Station (ISS) is much more difficult to maintain and upgrade and its failure rate has been constant over time. The ISS Carbon Dioxide Removal Assembly (CDRA) reliability has slightly decreased. Failures on ISS and with the ISS CDRA continue to be a challenge.

  16. Radioisotope heaters for spacecraft life support systems

    International Nuclear Information System (INIS)

    Future manned space flight requires the sanitary collection and disposal of biological wastes to minimize microbial contamination hazard. The recovery and reuse of water from such wastes are also necessary to reduce the weight of vehicles at launching and resupply logistics. The development and test of an engineering model, i.e. the completely integrated waste management-water system using radioisotopes for thermal energy, are described. This is capable of collecting and processing the wastes from four men during 180-day simulated space mission. The sub-systems include collection of feces, trash and urine, water reclamation, the storage, heating and dispensing of the water, and the disposal of feces, urine residue and other non-metallic waste material by incineration. (Mori, K.)

  17. Mobile 3D Viewer Supporting RFID System

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J. J.; Yang, S. W.; Choi, Y. [Chungang Univ., Seoul (Korea, Republic of)

    2007-07-01

    As hardware capabilities of mobile devices are being rapidly enhanced, applications based upon mobile devices are also being developed in wider areas. In this paper, a prototype mobile 3D viewer with the object identification through RFID system is presented. To visualize 3D engineering data such as CAD data, we need a process to compute triangulated data from boundary based surface like B-rep solid or trimmed surfaces. Since existing rendering engines on mobile devices do not provide triangulation capability, mobile 3D programs have focused only on an efficient handling with pre-tessellated geometry. We have developed a light and fast triangulation process based on constrained Delaunay triangulation suitable for mobile devices in the previous research. This triangulation software is used as a core for the mobile 3D viewer on a PDA with RFID system that may have potentially wide applications in many areas.

  18. Mobile 3D Viewer Supporting RFID System

    International Nuclear Information System (INIS)

    As hardware capabilities of mobile devices are being rapidly enhanced, applications based upon mobile devices are also being developed in wider areas. In this paper, a prototype mobile 3D viewer with the object identification through RFID system is presented. To visualize 3D engineering data such as CAD data, we need a process to compute triangulated data from boundary based surface like B-rep solid or trimmed surfaces. Since existing rendering engines on mobile devices do not provide triangulation capability, mobile 3D programs have focused only on an efficient handling with pre-tessellated geometry. We have developed a light and fast triangulation process based on constrained Delaunay triangulation suitable for mobile devices in the previous research. This triangulation software is used as a core for the mobile 3D viewer on a PDA with RFID system that may have potentially wide applications in many areas

  19. Addressing Consent Issues in Donation After Circulatory Determination of Death.

    Science.gov (United States)

    Overby, Kim J; Weinstein, Michael S; Fiester, Autumn

    2015-01-01

    Given the widening gap between the number of individuals on transplant waiting lists and the availability of donated organs, as well as the recent plateau in donations based on neurological criteria (i.e., brain death), there has been a growing interest in expanding donation after circulatory determination of death. While the prevalence of this form of organ donation continues to increase, many thorny ethical issues remain, often creating moral distress in both clinicians and families. In this article, we address one of these issues, namely, the challenges surrounding patient and surrogate informed consent for donation after circulatory determination of death. First we discuss several general concerns regarding consent related to this form of organ donation, and then we address additional issues that are unique to three different patient categories: adult patients with medical decision-making capacity or potential capacity, adult patients who lack capacity, and pediatric patients. PMID:26225503

  20. System Administration Support/SWORDS G2

    Science.gov (United States)

    Dito, Scott Joseph

    2014-01-01

    The Soldier-Warfighter Operationally Responsive Deployer for Space (SWORDS) rocket is a dedicated small satellite launcher that will minimize danger and complexity in order to allow soldiers in the field to put payloads of up to 25kg into orbit from the field. The SWORDSG2 project is the development of a model, simulation, and ultimately a working application that will control and monitor the cryogenic fluid delivery to the SWORDS rocket for testing purposes. To accomplish this, the project is using the programming language environment Gensym G2. The environment is an all-inclusive application that allows development, testing, modeling, and finally operation of the unique application through graphical and programmatic methods. In addition, observation of the current cryogenic fluid delivery system in the Kennedy Space Center Cry Lab has allowed me to gain valuable experience of fluid systems and propelant delivery that is valuable to our team when developing amd modeling our own system.The ultimate goal of having a test-ready application to show to the heads of the project, and demonstrating G2's capabilities, by late 2014 will require hard work and intense study and understanding of not only the programming aspect but also the physical phenomena we want to model, observe, and control.

  1. Fusion-supported decentralized nuclear energy system

    International Nuclear Information System (INIS)

    A decentralized nuclear energy system is proposed comprising mass-produced pressurized water reactors in the size range 10 to 300 MW (thermal), to be used for the production of process heat, space heat, and electricity in applications where petroleum and natural gas are presently used. Special attention is given to maximizing the refueling interval with no interim batch shuffling in order to minimize fuel transport, reactor downtime, and opportunity for fissile diversion. These objectives demand a substantial fissile enrichment (7 to 15%). The preferred fissile fuel is U-233, which offers an order of magnitude savings in ore requirements (compared with U-235 fuel), and whose higher conversion ratio in thermal reactors serves to extend the period of useful reactivity and relieve demand on the fissile breeding plants (compared with Pu-239 fuel). Application of the neutral-beam-driven tokamak fusion-neutron source to a U-233 breeding pilot plant is examined. This scheme can be extended in part to a decentralized fusion energy system, wherein remotely located large fusion reactors supply excess tritium to a distributed system of relatively small nonbreeding D-T reactors

  2. Fusion-supported decentralized nuclear energy system

    International Nuclear Information System (INIS)

    A decentralized nuclear energy system is proposed comprising mass-produced pressurized water reactors in the size range 10 to 300 MW (thermal), to be used for the production of process heat, space heat, and electricity in applications where petroleum and natural gas are presently used. Special attention is given to maximizing the refueling interval with no interim batch shuffling in order to minimize fuel transport, reactor downtime, and opportunity for fissile diversion. The smallest reactors could be deployed as nuclear batteries, kept in the equivalent of spent-fuel shipping casks and returned to nuclear fuel centers for refueling. These objectives demand a substantial fissile enrichment (7 to 15%). The preferred fissile fuel is U-233, which offers an order of magnitude savings in ore requirements (compared with U-235 fuel), and whose higher conversion ratio in thermal reactors serves to extend the period of useful reactivity and relieve demand on the fissile breeding plants (compared with Pu-239 fuel). Application of the neutral-beam-driven tokamak fusion-neutron source to a U-233 breeding pilot plant is examined. This scheme can be extended in part to a decentralized fusion energy system, wherein remotely located large fusion reactors supply excess tritium to a distributed system of relatively small nonbreeding D-T reactors

  3. Intelligent Information System to support decision making.

    Directory of Open Access Journals (Sweden)

    Kathrin Rodríguez Llanes

    2010-06-01

    Full Text Available Making decisions is complicated in a generalized way, the materials and humans resources of the entity we belong to depends on it, such as the fulfillment of its goals. But when the situations are complex, making decisions turns into a very difficult work, due to the great amount of aspects to consider when making the right choice. To make this efficiently the administration must to consult an important volume of information, which generally, is scattered and in any different formats. That’s why appears the need of developing software that crowd together all that information and be capable of, by using powerful search engines and process algorithms improve the good decisions making process. Considering previous explanation, a complete freeware developed product is proposed, this constitutes a generic and multi-platform solution, that using artificial intelligence techniques, specifically the cases based reasoning, gives the possibility to leaders of any institution or organism of making the right choice in any situation.With client-server architecture, this system is consumed from web as a service and it can be perfectly integrated with a management system or the geographic information system to facilitate the business process.

  4. A Framework for Awareness support in Groupware Systems

    OpenAIRE

    Kirsch-Pinheiro, Manuele; De Lima, José Valdeni; Borges, Marcos

    2003-01-01

    This paper introduces a framework for awareness support in groupware systems. Awareness gathers the group knowledge, its activities and its overall status. Awareness support is an important feature for groupware systems. It provides a context for individual contributions, improving these contributions and avoiding contradictory interactions among group members. Despite its importance, awareness support is not systematic and developers must build it from scratch for each new application. The f...

  5. ACCOUNTING KNOWLEDGE IN FORESTRY'S DECISION SUPPORT SYSTEMS. LITERATURE REVIEW

    OpenAIRE

    Daniela I. POSTOLACHE (MALES)

    2010-01-01

    Accounting information, processed through modern type of decision support systems, in appropriate economic analysis framework, using previous experience, gives extra knowledge to forestry managers. In our paper, we conducted a literature review, in the field of decision support systems used in international forestry, but also about the Romanian prospects and achievements in this area. Our results are useful to researchers and developers of decision support intelligent solutions, to forestry a...

  6. Specification Language NUJSL Based on JSP and Its Supporting System

    Institute of Scientific and Technical Information of China (English)

    徐永森; 何飚

    1992-01-01

    is paper presents the specification languange NUJSL and its supporting system.NUJSL is a modular specification language based on Jackson Program Design Method(JSP).With the module construction,it is convenient to use NUJSL to write larger specifications.The supporting system supports the incremental development of software specification in NUJSL,and implements the transformation both from specification to software procedural description in Jackson Schematic Logic(pseudo code)and from procedural description to PASCAL program.

  7. PEGASUS: Designing a System for Supporting Group Activity

    Science.gov (United States)

    Kyprianidou, Maria; Demetriadis, Stavros; Pombortsis, Andreas; Karatasios, George

    2009-01-01

    Purpose: The purpose of this paper is to present the design and first results of the integration of a web-based system person-centred group-activity support system (PEGASUS) in university instruction, as a means for advancing person-centred learning by supporting group activity. The PEGASUS is expected to help students and teachers in two distinct…

  8. Fault-Tolerant Onboard Monitoring and Decision Support Systems

    DEFF Research Database (Denmark)

    Lajic, Zoran

    The purpose of this research project is to improve current onboard decision support systems. Special focus is on the onboard prediction of the instantaneous sea state. In this project a new approach to increasing the overall reliability of a monitoring and decision support system has been...

  9. Artificial and bioartificial support systems for liver failure

    DEFF Research Database (Denmark)

    Liu, J P; Gluud, L L; Als-Nielsen, B;

    2004-01-01

    Artificial and bioartificial liver support systems may 'bridge' patients with acute or acute-on-chronic liver failure to liver transplantation or recovery.......Artificial and bioartificial liver support systems may 'bridge' patients with acute or acute-on-chronic liver failure to liver transplantation or recovery....

  10. Providing over-the-horizon awareness to driver support systems

    NARCIS (Netherlands)

    Eenennaam, van Martijn; Heijenk, Geert

    2008-01-01

    Vehicle-to-vehicle communications is a promising technique for driver support systems to increase traffic safety and efficiency. A proposed system is the Congestion Assistant [1], which aims at supporting drivers when approaching and driving in a traffic jam. Studies have shown great potential for the Con

  11. A Comparative Study of Electronic Performance Support Systems

    Science.gov (United States)

    Nguyen, Frank; Klein, James D.; Sullivan, Howard

    2005-01-01

    Electronic performance support systems (EPSS) deliver relevant support information to users while they are performing tasks. The present study examined the effect of different types of EPSS on user performance, attitudes, system use and time on task. Employees at a manufacturing company were asked to complete a procedural software task and…

  12. A Study on Simulation of Aircraft Maintenance and Support System

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Maintenance and support are basic elements to realize the effectiveness of aircraft. For basic analysis of the characteristics of an aircraft maintenance and support system, a simulation method is presented in this paper, and the structure and realization ofthe simulation system is discussed.

  13. Fault Detection for Shipboard Monitoring and Decision Support Systems

    DEFF Research Database (Denmark)

    Lajic, Zoran; Nielsen, Ulrik Dam

    2009-01-01

    In this paper a basic idea of a fault-tolerant monitoring and decision support system will be explained. Fault detection is an important part of the fault-tolerant design for in-service monitoring and decision support systems for ships. In the paper, a virtual example of fault detection will be p...

  14. Antibiotics can ameliorate circulatory complications of liver cirrhosis

    DEFF Research Database (Denmark)

    Madsen, Bjørn Stæhr; Schaffalitzky de Muckadell, Ove B

    2011-01-01

    Livercirrhosis can be complicated by a hyperdynamic circulatory syndrome. This is due to translocation of bacteria and bacterial product (bacterial DNA and endotoxins), which stimulate the splanchnic nitric oxide synthase and leads to splanchnic vasodilatation and haemodynamic derangement. This...... review focuses on how broad spectrum antibiotics can ameliorate the haemodynamic consequences of bacterial translocation. It is possible that the use of broad spectrum antibiotics in the future may be used to prevent other complications of liver cirrhosis than spontaneous bacterial peritonitis and...

  15. Development of a group support system to support collaborative works in value management workshops

    Institute of Scientific and Technical Information of China (English)

    SHEN Qi-ping; CHUNG J K H; LI Heng

    2004-01-01

    Value Management (VM) is a rigorous and systematic approach to improve the value and optimise the overall cost of a facility. It identifies opportunities to remove unnecessary costs while assuring that quality,reliability, performance, and other critical factors will meet or exceed the customers′ expectations. It has been widely used in the construction industry in a number of countries. A recent survey, however, revealed several problems that hinder the wider use of this methodology in the industry. To overcome these problems, a feasibility study has been conducted to investigate whether or not a Group Support System (GSS) can support collaborative works in VM workshops. This paper introduces the development and structure of a prototype GSS which is designed to support the collaborative works of stakeholders in VM workshops. It begins with an introduction to the conceptual GSS framework and job plan, illustrating what GSS supports can be provided to VM workshops.This is followed by a detailed description of the GSS prototype system to demonstrate how these supports can be performed as an integrated computer system. The testing of the system is also discussed. The research findings provide strong evidence in supporting the notion of using GSS to improve VM implementation. The information support of GSS has been ranked to be the most useful GSS functions and most of the practitioners interviewed are highly interested in applying GSS to support VM workshops in the future.

  16. Improving Planning Support : The use of planning support systems for spatial planning

    NARCIS (Netherlands)

    Vonk, Guido Antonius

    2006-01-01

    Spatial planning is one of the most complex activities of public organizations. Since approximately halfway the 1990s a new generation of geo-information technologies has become available to support those involved in planning in handling the complexity: Planning Support Systems (PSS). PSS consist of

  17. Intelligent Flight Support System (IFSS): A Real-time Intelligent Decision Support Prototype Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The integration of the analysis tools with the advanced visualization capabilities in The Intelligent Flight Support System (IFSS) can provide a unique method for...

  18. Vibrational characteristics of fluid filled gap support systems

    International Nuclear Information System (INIS)

    A fluid filled gap support system is a hydrodynamic support system, which is composed of an inner cylinder and an outer restraint cylinder surrounding the inner cylinder, with a small gap between them filled with fluid. In pool type LMFBRs, the fluid filled gap support system is considered to be efficient as a seismic support system for internal components, such as pumps, IHXs etc., which are suspended from the deck. Because this support system has no mechanical connections with internal components, and accommodates the thermal deformation without causing thermal stress. This support system fundamentally has a two concentric cylindrical geometry separated by an annular fluid region. Previously, two dimensional analyses on this cylindrical structure were performed, neglecting axial flows in the annular region, by Fritz and Chen. It has been proved analytically and experimentally that the fluid filled gap support system was effective to restrain component vibration, and that axial flows in the annular gap reduced supporting effects. So, it is expected that the system will be improved in performance by suppressing axial flows in the annular gap. In this study, a device using seal rings was designed to suppress the axial flow described above. Analyses were performed to evaluate vibrational characteristics for the system, such as added mass and damping factors. Also, vibration tests with the seal rings were performed to examine the validity of the analytical method, and vibration test without the seal rings were performed in a large response amplitude to examine the vibration characteristics. Finally, a design calculation for a core support cylinder was performed for the evaluation of support systems. 5 refs, 12 figs, 2 tabs

  19. Research on Development of Corn Production Decision Support System

    Directory of Open Access Journals (Sweden)

    Nan Lin

    2013-07-01

    Full Text Available This research was about the application of decision support system in agriculture. The subject of study was the corn cultivated in Jilin province, northeast of China. The research synthesized expertise and experience on corn cultivation, plant protection, soil and fertilizer, and synthesized agriculture ecology from experts, integrating computer technology, principle of decision support system with corn production knowledge. The research also concerned decision support system for corn fertilization and diagnosis of insect disease and weed harming, which included system concept design, database design, knowledge base design , model base design and preliminary inference engine design according to the characteristics of corn diseases and pests of weeds.  

  20. Development of cooperative work support system for nuclear power plants

    International Nuclear Information System (INIS)

    In a nuclear power plant, there are various staff members for plant control and maintenance, and they have different specialties and work in different places. In past systems, each system supported one task in the different sections. The authors think that collaboration among staff members is very important to decrease the staff workload. Therefore they have been developing a cooperative work support system for nuclear power plants, to realize effective communication between plant staff in distant places. This system provides the functions for sharing various plant information and supporting group decision, using multimedia technology and knowledge engineering

  1. Risk Interfaces to Support Integrated Systems Analysis and Development

    Science.gov (United States)

    Mindock, Jennifer; Lumpkins, Sarah; Shelhamer, Mark; Anton, Wilma; Havenhill, Maria

    2016-01-01

    Objectives for systems analysis capability: Develop integrated understanding of how a complex human physiological-socio-technical mission system behaves in spaceflight. Why? Support development of integrated solutions that prevent unwanted outcomes (Implementable approaches to minimize mission resources(mass, power, crew time, etc.)); Support development of tools for autonomy (need for exploration) (Assess and maintain resilience -individuals, teams, integrated system). Output of this exercise: -Representation of interfaces based on Human System Risk Board (HSRB) Risk Summary information and simple status based on Human Research Roadmap; Consolidated HSRB information applied to support communication; Point-of-Departure for HRP Element planning; Ability to track and communicate status of collaborations. 4

  2. Development of a modelling platform. The circulatory model: a tool for research and education in cardiovascular patho-physiology.

    OpenAIRE

    Ferrari, Gianfranco; Kozarski, Maciej; Zielinski, Krzysztof; Avis, Charlotte; Gorczynska, Krystyna; Palko, Krzysztoff Jakub; Darowski, Marek

    2009-01-01

    Objectives: The aim of this work is the development of a modelling platform with hybrid capabilities: that is to say, its structure can be modified according to the experimental needs merging, if necessary, numerical models and physical devices or models that can be indifferently hydraulic or electrical. The numerical circulatory model is an important part of the platform. It can be applied as a fully numerical model or as a part of a hybrid system.

  3. Marketing Management Support Systems: evolution, adoption and effectiveness

    OpenAIRE

    Wierenga, Berend; Bruggen, Gerrit

    1995-01-01

    textabstractA Marketing Management Support Systems can be defined as any device combining (i) information technology, (ii) marketing data and/ or knowledge, and (iii) analytical capabilities, made available to one or more marketing decision-makers with the objective to improve the quality of marketing decision-making. In this paper we present a categorization scheme for marketing management support systems. Three types of MMSS, developed so far, can be identified: marketing information system...

  4. Customer Participation in the Support System for Small Grocery Retailers

    OpenAIRE

    Dawson, John; Terashima, Kazuo

    2004-01-01

    In the previous research (Terashima and Dawson, 2004), we discussed a support system for small grocery retailers in order to regenerate them. The purpose of this paper is to show a mechanism which increases customer value of the support system by focusing on customer participation, because increasing customer value has a high priority as the next step for the system. In this paper, we first show that customer participation can be related to customer value through service quality. ...

  5. Instrumentation and control activities at the electric power research institute to support computerized support systems

    International Nuclear Information System (INIS)

    Most nuclear power plants in the United States are operating with their original analog I and C equipment. This equipment requires increasing maintenance efforts to sustain systems performance. Decreasing availability of replacement parts and support organization for analog technology accentuate obsolescence problems and resultant O and M cost increases. Modern technology, especially digital systems, offers improved functionality, performance, and reliability; solutions to obsolescence of equipment; reduction in O and M costs; and the potential to enhance safety. Digital systems, including computerized support systems, with their inherent advantages will be implemented only if reliable and cost-effective implementation and licensing acceptance is achieved and if the upgraded systems supports reduced power production costs. EPRI and its member utilities are working together under the Integrated I and C Upgrade Initiative to address I and C issues. (author). 23 refs

  6. Circulatory response to hyperthermia during acute normovolaemic haemodilution

    Science.gov (United States)

    Talwar, Anita; Fahim, M.

    Cats anaesthetized with a mixture of chloralose and urethane were exposed to heat stress in two groups. In the first group (n=10) of control animals, the effect of heat stress on haemodynamic variables was recorded at control haematocrit (HCT) of 42.0+/-1.0%. In a second group, the effect of heat stress was studied after induction of acute normovolaemic haemodilution (HCT of 13.0+/-1.0%). Haemodilution was induced to a maximum of 60% replacement of blood with dextran (mol.wt. 150000). Heat stress was induced by surface heating and core body temperature was raised from 37° C to 42° C. The effect of heat stress and haemodilution on various haemodynamic variables, viz. left ventricular pressure (LVP), left ventricular contractility (LVdP/dtmax), heart rate (HR), cardiac output (CO), arterial blood pressure (ABP), right atrial pressure (RAP), and arterial blood PO2, PCO2 and pH was examined. Haemodilution produced significant (P0.05) changes in ABP, RAP, LVdP/dtmax and total peripherial resistance (TPR). Hyperthermia caused a significant fall (P<0.05) in TPR. However, the percentage fall in TPR was higher in the control group. On exposure to heat stress, there were significant (P<0.05I increases in HR and CO in both the groups; however, HR and CO values were significantly (P<0.05) higher in the haemodiluted group compared to the control. The latter findings could be due either to the higher basal values of these variables with the fall in HCT or to inefficient cardiovascular regulatory mechanisms. The lack of efficient regulatory control under such severe stress conditions makes the cardiovascular system of anaemic animals more vulnerable to heat stress. In conclusion, the results of the present study showed deleterious effects of heat stress in both the groups. The higher values of HR and CO in the haemodiluted group may be responsible for circulatory failure at low HCT values, indicating a higher risk in the haemodiluted group as compared to the control group.

  7. Instrumentation and control activities at the Electric Power Research Institute to support operator support systems

    International Nuclear Information System (INIS)

    Most nuclear power plants in the United States continue to operate with analog instrumentation and control (I and C) technology designed 20 to 40 years ago. This equipment is approaching or exceeding its life expectancy, resulting in increasing maintenance efforts to sustain system performance. Decreasing availability of replacement parts and the accelerating deterioration of the infrastructure of manufacturers that support analog technology exacerbate obsolescence problems and resultant operation and maintenance (O and M) cost increases. Modern digital technology holds a significant potential to improve the safety, cost-effectiveness, productivity, and, therefore, competitiveness of nuclear power plants. Operator support systems provide the tools to help achieve this potential. Reliable, integrated information is a critical element for protecting the utility's capital investment and increasing availability, reliability, and productivity. Integrated operator support systems with integrated information can perform more effectively to increase productivity, to enhance safety, and to reduce O and M costs. The plant communications and computing architecture is the infrastructure needed to allow the implementation of I and C systems and associated operator support systems in an integrated manner. Current technology for distributed digital systems, plant process computers, and plant communications and computing networks support the integration of systems and information. (author). 16 refs

  8. Design Evolution and Analysis of the ITER Cryostat Support System

    Science.gov (United States)

    Xie, Han; Song, Yuntao; Wang, Songke

    2015-12-01

    The cryostat is a vacuum tight container enveloping the entire basic systems of the ITER tokamak machine, including a vacuum vessel, a superconducting magnet and thermal shield etc. It is evacuated to a pressure of 10-4 Pa to limit the heat transfer via gas conduction and convection to the cryogenically cooled components. Another important function of cryostat is to support all the loads from the tokamak to the concrete floor of the pit by its support system during different operational regimes and accident scenarios. This paper briefly presents the design evolution and associated analysis of the cryostat support system and the structural interface with the building.

  9. Decision Support Systems - Technical Prerequisites and Military Requirements

    CERN Document Server

    Tolk, Andreas

    2010-01-01

    Decision Support Systems in the sense of online alternative course of action (ACAO) development and analysis as well as tools for online Development of Doctrine and Tactics Techniques, and Procedures (DTTP) for support to operations make it possible to evaluate and forecast the command and control processes and the performance capabilities of the friendly and enemy forces and other decision relevant factors, support the military commander (brigade and higher) and his staff in their headquarter by increasing their ability to identify own opportunities, support all phases of the command and control process, use computer based, automatic and closed models, that can be adapted to the current situation. Objective of the paper is to present the results of studies conducted in Germany on behalf of the German Ministry of Defense with the objective to work out the conceptual basis for decision support systems and to evaluate, how this technique will influence the command and control system of the army of the federal a...

  10. Modification of the JET vacuum vessel support and restraint system

    International Nuclear Information System (INIS)

    Since 1983, after the first plasma vertical instability, the support and restraint system has been continuously modified and upgraded to cope with the new design and operational requirement. Fig. 1 shows how the vessel supports and restraints have changed over the life of JET. With the divertor phase, new loads are applied to the vacuum vessel supports and restraints leading to a revision of the complete system. The elastic suspensions at the equatorial plane have been modified to cope with the increase in vessel weight. The vessel restraints have been modified and tested to cope with the new electromagnetic load in equilibrium and plasma instability. This paper briefly describes the overall philosophy of the vessel support system, the modification and the tests that have been done. Some experimental results are also reported on the behaviour of the supports and restraints. (orig.)

  11. Decision Support Systems for Research and Management in Advanced Life Support

    Science.gov (United States)

    Rodriquez, Luis F.

    2004-01-01

    Decision support systems have been implemented in many applications including strategic planning for battlefield scenarios, corporate decision making for business planning, production planning and control systems, and recommendation generators like those on Amazon.com(Registered TradeMark). Such tools are reviewed for developing a similar tool for NASA's ALS Program. DSS are considered concurrently with the development of the OPIS system, a database designed for chronicling of research and development in ALS. By utilizing the OPIS database, it is anticipated that decision support can be provided to increase the quality of decisions by ALS managers and researchers.

  12. Development of intelligent operator support systems by GRS

    International Nuclear Information System (INIS)

    This paper describes the technical and ergomonic background, the current state and future trends in the development of intelligent operator support systems by GRS. Moreover, the influence of these advanced support systems on the design of control rooms will be briefly discussed. The degree and scope of automation has a high influence on the information situation of the operating personnel. Attempt is made to characterize the situation in current German NPP's and to describe the rationale for the various GRS system-developments. Following this the developed system concepts are explained, which comprise systems for a computerized operation manual, for post trip analysis, for alarm reduction and for disturbance analysis

  13. Argentina's operator support systems in nuclear power plants

    International Nuclear Information System (INIS)

    The development of operator support systems for nuclear power plants started in Argentina a few years ago. Four systems are at present deployed or under development. The participation of utility personnel in the co-ordinated research program has helped in revising the current experience and in selecting and specifying the systems to be developed and the resources needed for their implementation. Main efforts will be aimed to the selection of those systems that can be more easily implemented, to improve the data retrieval and handling, to develop diverse supplies of software products and to promote the understanding of support systems among the potential end users. (author). 12 refs

  14. On the heuristic nature of medical decision-support systems.

    Science.gov (United States)

    Aliferis, C F; Miller, R A

    1995-03-01

    In the realm of medical decision-support systems, the term "heuristic systems" is often considered to be synonymous with "medical artificial intelligence systems" or with "systems employing informal model(s) of problem solving". Such a view may be inaccurate and possibly impede the conceptual development of future systems. This article examines the nature of heuristics and the levels at which heuristic solutions are introduced during system design and implementation. The authors discuss why heuristics are ubiquitous in all medical decision-support systems operating at non-trivial domains, and propose a unifying definition of heuristics that encompasses formal and ad hoc systems. System developers should be aware of the heuristic nature of all problem solving done in complex real world domains, and characterize their own use of heuristics in describing system development and implementation. PMID:9082138

  15. Human Health and Support Systems Capability Roadmap Progress Review

    Science.gov (United States)

    Grounds, Dennis; Boehm, Al

    2005-01-01

    The Human Health and Support Systems Capability Roadmap focuses on research and technology development and demonstration required to ensure the health, habitation, safety, and effectiveness of crews in and beyond low Earth orbit. It contains three distinct sub-capabilities: Human Health and Performance. Life Support and Habitats. Extra-Vehicular Activity.

  16. Developing a Decision Support System: The Software and Hardware Tools.

    Science.gov (United States)

    Clark, Phillip M.

    1989-01-01

    Describes some of the available software and hardware tools that can be used to develop a decision support system implemented on microcomputers. Activities that should be supported by software are discussed, including data entry, data coding, finding and combining data, and data compatibility. Hardware considerations include speed, storage…

  17. Scaffolding Strategies in Electronic Performance Support Systems: Types and Challenges

    Science.gov (United States)

    Cagiltay, Kursat

    2006-01-01

    In the study described in this paper, the major components of an electronic performance support system are described and the use of scaffolding techniques within such electronic environments is explored. Four different types of scaffolding are discussed: "conceptual" (supportive) scaffolding, "metacognitive" (reflective) scaffolding, "procedural"…

  18. A System for Supporting Cross-Lingual Information Retrieval.

    Science.gov (United States)

    Capstick, Joanne; Diagne, Abdel Kader; Erbach, Gregor; Uszkoreit, Hans; Leisenberg, Anne; Leisenberg, Manfred

    2000-01-01

    Describes the MULINEX system that supports cross-lingual searching of the World Wide Web. Users can formulate queries, filter the search results and read documents by using their native language. Discusses dictionary-based query translation, multilingual document categorization, and automatic translation that supports French, German, and English.…

  19. Designing Work Support Systems – For and With Skilled Users

    OpenAIRE

    Olsson, Eva

    2004-01-01

    Computer users often suffer from poorly designed support systems that hinder them from performing their work efficiently and with satisfaction. The evidence is found in observations of users at work, interviews, evaluations of systems, and numerous reports of systems with poor usability that fail from start. Those who use the systems are proficient in their work, and those who develop systems are proficient in software engineering. These two groups have often little knowledge and understandin...

  20. Middleware Fault Tolerance Support for the BOSS Embedded Operating System

    OpenAIRE

    Afonso, Francisco; Carlos A. Silva; Montenegro, Sérgio; Tavares, Adriano

    2006-01-01

    Critical embedded systems need a dependable operating system and application. Despite all efforts to prevent and remove faults in system development, residual software faults usually persist. Therefore, critical systems need some sort of fault tolerance to deal with these faults and also with hardware faults at operation time. This work proposes fault-tolerant support mechanisms for the BOSS embedded operating system, based on the application of proven fault tolerance strategies by middlew...

  1. IAEA activity on operator support systems in nuclear power plants

    International Nuclear Information System (INIS)

    Various operator support systems for nuclear power plants are already operational or under development in the IAEA Member States. Operator support systems are based on intelligent data processing and, in addition to plant operation, they are also becoming more important for safety. A key feature of operator support systems is their availability to restructure data to increase its relevance for a given situation. This can improve the user's ability to identify plant mode, system state, and component state and to identify and diagnose faults. Operator support systems can also assist the user in planning and implementing corrective actions to improve the nuclear power plant's availability and safety. In September 1991, the IAEA Committee for Contractual Scientific Services approved the Co-ordinated Research Programme (CRP) on ''Operator Support Systems in Nuclear Power Plants'' in the framework of the Project ''Man-Machine Interface Studies''. The main objective of this programme is to provide guidance and technology transfer for the development and implementation of operator support systems. This includes the experience with human-machine interfaces and closely related issues such as instrumentation and control, the use of computers in nuclear power plants, and operator qualification. (author)

  2. SUPPORTING SALESPERSONS' CRM EFFORTS THROUGH LOCATION-BASED MOBILE SUPPORT SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    Chihab BENMOUSSA

    2005-01-01

    This paper aims at assessing how location-based mobile support systems can support salespersons' CRM efforts when they are operating within a highly mobile work environment. After briefly discussing the state-of-the-art issues associated with mobile location technologies, the paper conceptualizes key dimensions for location-based mobile support systems. The paper then discusses the dual role of salespersons in CRM. A fourth section suggests a categorization of salespersons'CRM tasks based on both properties of location-based mobile support and the areas of salespersons'CRM-related tasks that may be affected by mobile location technologies. Finally, the paper suggests potential mobile location services and applications that can help salespersons perform effectively their everyday CRM tasks and link such applications to the determinant of salespersons' performance. The paper concludes with a discussion of some critical issues and suggests areas for further research.

  3. THE INTRODUCTION OF INFORMATION SUPPORT INNOVATION SYSTEM IN THE ENTERPRISE

    OpenAIRE

    Netreba, I.

    2013-01-01

    The article considers the characteristics of information technology innovation enterprises, the factors that affect the implementation and use of information technology to support innovation and the main advantage of the information system of innovative processes in the enterprise.

  4. Guiding the development of a controlled ecological life support system

    Science.gov (United States)

    Mason, R. M. (Editor); Carden, J. L. (Editor)

    1979-01-01

    The workshop is reported which was held to establish guidelines for future development of ecological support systems, and to develop a group of researchers who understand the interdisciplinary requirements of the overall program.

  5. Decision support systems in oncology: Are we there yet?

    OpenAIRE

    D'Aquin, Mathieu; Lieber, Jean; Napoli, Amedeo

    2008-01-01

    This paper presents the experience of the Kasimir project in the domain on decision knowledge management in oncology and, more broadly, a discussion about decision support systems dedicated to oncology.

  6. Engineering Next Generation Launch Systems for Supportability Project

    Data.gov (United States)

    National Aeronautics and Space Administration — In order to meet the challenges of high probability of mission success for space exploration, ground support system for various launch operations that responds...

  7. Novel Composite Membrane for Space Life Supporting System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Space life-supporting systems require effective removal of metabolic CO2 from the cabin atmosphere with minimal loss of O2. Conventional techniques, using either...

  8. MODIS-Based Products for Operational Decision Support Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — SMH Consulting proposes to develop a web-based decision support system to assist in Rapid Assessment, Monitoring, and Management (RAMM-DSS) on a regional scale. SMH...

  9. A proposed ecosystem services classification system to support green accounting

    Science.gov (United States)

    There are a multitude of actual or envisioned, complete or incomplete, ecosystem service classification systems being proposed to support Green Accounting. Green Accounting is generally thought to be the formal accounting attempt to factor environmental production into National ...

  10. Marketing decision support systems: Adoption, use and satisfaction.

    NARCIS (Netherlands)

    Wierenga, B.; Oude Ophuis, P.A.M.

    1997-01-01

    This paper deals with marketing decision support systems (MDSS) in companies. In a conceptual framework five categories of factors are distinguished that potentially affect adoption, use, and satisfaction: external environment factors, organizational factors, task environment factors, user factors a

  11. Marketing Decision Support Systems: Adoption, Use and Satisfaction

    NARCIS (Netherlands)

    B. Wierenga (Berend); P.A.M. Oude Ophuis

    1997-01-01

    textabstractThis paper deals with marketing decision support systems (MDSS) in companies. In a conceptual framework five categories of factors are distinguished that potentially affect adoption, use, and satisfaction: external environment factors, organizational factors, task environment factors, us

  12. System software and software systems execution support environment

    CERN Document Server

    Rus, Teodor

    1994-01-01

    SYSTEM SOFTWARE AND SOFTWARE SYSTEMS: Concepts and Methodology is intended to offer a systematic treatment of the theory and practice of designing and implementing system software.The two volumes systematically develop and apply the systems methodology for software development. For that the concept of a system is analysed and various types of systems used in computer science are systematized into a concept of an ad hoc system that is suitable as a mechanism for software development. The kernel of this methodology consists of a systematic approach for ad hoc systems development (specification,

  13. Customer Decision Support Systems: Resources for Student Decision Making

    OpenAIRE

    Cara Okleshen Peters; David A. Bradbard; Mary C. Martin

    2005-01-01

    This paper highlights the potential of customer decision support systems (CDSS) to assist students in education-related decision making. Faculty can use these resources to more effectively advise students on various elements of college life, while students can employ them to more actively participate in their own learning and improve their academic experience. This conceptual paper summarizes consumer decision support systems (CDSS) concepts and presents exemplar websites students could utili...

  14. A Components Library System Model and the Support Tool

    Institute of Scientific and Technical Information of China (English)

    MIAO Huai-kou; LIU Hui; LIU Jing; LI Xiao-bo

    2004-01-01

    Component-based development needs a well-designed components library and a set of support tools.This paper presents the design and implementation of a components library system model and its support tool UMLCASE.A set of practical CASE tools is constructed.UMLCASE can use UML to design Use Case Diagram, Class Diagram etc.And it integrates with components library system.

  15. Computer support system for residential environment evaluation for citizen participation

    Institute of Scientific and Technical Information of China (English)

    GE Jian; TEKNOMO Kardi; LU Jiang; HOKAO Kazunori

    2005-01-01

    Though the method of citizen participation in urban planning is quite well established, for a specific segment of residential environment, however, existing participation system has not coped adequately with the issue. The specific residential environment has detailed aspects that need positive and high level involvement of the citizens in participating in all stages and every field of the plan. One of the best and systematic methods to obtain a more involved citizen is through a citizen workshop. To get a more "educated" citizen who participates in the workshop, a special session to inform the citizen on what was previously gathered through a survey was revealed to be prerequisite before the workshop. The computer support system is one of the best tools for this purpose. This paper describes the development of the computer support system for residential environment evaluation system, which is an essential tool to give more information to the citizens before their participation in public workshop. The significant contribution of this paper is the educational system framework involved in the workshop on the public participation system through computer support, especially for residential environment. The framework, development and application of the computer support system are described. The application of a workshop on the computer support system was commented on as very valuable and helpful by the audience as it resulted in greater benefit to have wider range of participation, and deeper level of citizen understanding.

  16. The Systems Engineering Process for Human Support Technology Development

    Science.gov (United States)

    Jones, Harry

    2005-01-01

    Systems engineering is designing and optimizing systems. This paper reviews the systems engineering process and indicates how it can be applied in the development of advanced human support systems. Systems engineering develops the performance requirements, subsystem specifications, and detailed designs needed to construct a desired system. Systems design is difficult, requiring both art and science and balancing human and technical considerations. The essential systems engineering activity is trading off and compromising between competing objectives such as performance and cost, schedule and risk. Systems engineering is not a complete independent process. It usually supports a system development project. This review emphasizes the NASA project management process as described in NASA Procedural Requirement (NPR) 7120.5B. The process is a top down phased approach that includes the most fundamental activities of systems engineering - requirements definition, systems analysis, and design. NPR 7120.5B also requires projects to perform the engineering analyses needed to ensure that the system will operate correctly with regard to reliability, safety, risk, cost, and human factors. We review the system development project process, the standard systems engineering design methodology, and some of the specialized systems analysis techniques. We will discuss how they could apply to advanced human support systems development. The purpose of advanced systems development is not directly to supply human space flight hardware, but rather to provide superior candidate systems that will be selected for implementation by future missions. The most direct application of systems engineering is in guiding the development of prototype and flight experiment hardware. However, anticipatory systems engineering of possible future flight systems would be useful in identifying the most promising development projects.

  17. Integration of emergency data management and decision support systems

    International Nuclear Information System (INIS)

    Integrated Emergency Data Management and Decision Support System for Nuclear Emergencies (EDMDSS) is being developed by the Institute of Atomic Energy (IAE) under supervision of the National Atomic Energy Agency (NAEA), as a part of an overall National Safety System for Poland. Organisational features and technical capacities for radiological data acquisition are presented, and their evaluation for assessment of current radiological situation in Poland is discussed. Transboundary data exchange and a concept of an integrated national system for emergency data acquisition and management is proposed. A radiological situation prediction and decision support system is described. (author)

  18. Prediction of Banking Systemic Risk Based on Support Vector Machine

    Directory of Open Access Journals (Sweden)

    Shouwei Li

    2013-01-01

    Full Text Available Banking systemic risk is a complex nonlinear phenomenon and has shed light on the importance of safeguarding financial stability by recent financial crisis. According to the complex nonlinear characteristics of banking systemic risk, in this paper we apply support vector machine (SVM to the prediction of banking systemic risk in an attempt to suggest a new model with better explanatory power and stability. We conduct a case study of an SVM-based prediction model for Chinese banking systemic risk and find the experiment results showing that support vector machine is an efficient method in such case.

  19. EXPLOITATION OF LIFE SUPPORT SYSTEMS IN POPULATED PLACES

    Directory of Open Access Journals (Sweden)

    Rudchenko I. I.

    2015-10-01

    Full Text Available This article describes aspects of control, regulation, functioning and degree of influence on the condition of life-support systems, on the safety of life support, on the safety vital functions of society. The impact of life-support systems on the ecological status of builtup areas. The article refers to an increase in emissions and the dangers of СО2 и SО2, about methods to reduce them. It presents the dangers of hydrogen compounds, nitrogen, chlorine, freon. We have also presented measures to protect the environment in urban areas

  20. MPI support in the DIRAC Pilot Job Workload Management System

    International Nuclear Information System (INIS)

    Parallel job execution in the grid environment using MPI technology presents a number of challenges for the sites providing this support. Multiple flavors of the MPI libraries, shared working directories required by certain applications, special settings for the batch systems make the MPI support difficult for the site managers. On the other hand the workload management systems with Pilot Jobs became ubiquitous although the support for the MPI applications in the Pilot frameworks was not available. This support was recently added in the DIRAC Project in the context of the GISELA Latin American Grid Initiative. Special services for dynamic allocation of virtual computer pools on the grid sites were developed in order to deploy MPI rings corresponding to the requirements of the jobs in the central task queue of the DIRAC Workload Management System. Pilot Jobs using user space file system techniques install the required MPI software automatically. The same technique is used to emulate shared working directories for the parallel MPI processes. This makes it possible to execute MPI jobs even on the sites not supporting them officially. Reusing so constructed MPI rings for execution of a series of parallel jobs increases dramatically their efficiency and turnaround. In this contribution we describe the design and implementation of the DIRAC MPI Service as well as its support for various types of MPI libraries. Advantages of coupling the MPI support with the Pilot frameworks are outlined and examples of usage with real applications are presented.

  1. A new scenario based approach for designing driver support systems applied to the design of a lane change support system

    NARCIS (Netherlands)

    Tideman, Martijn; Voort, van der Mascha; Arem, van Bart

    2010-01-01

    Designing a new driver support system that meets the expectations of drivers is a difficult and time-consuming process. Despite the availability of various types of design support, it has essentially remained a process in which designers are forced to make assumptions about what other people want. T

  2. Liver Transplant From Unexpected Donation After Circulatory Determination of Death Donors: A Challenge in Perioperative Management.

    Science.gov (United States)

    Blasi, A; Hessheimer, A J; Beltrán, J; Pereira, A; Fernández, J; Balust, J; Martínez-Palli, G; Fuster, J; Navasa, M; García-Valdecasas, J C; Taurá, P; Fondevila, C

    2016-06-01

    Unexpected donation after circulatory determination of death (uDCD) liver transplantation is a complex procedure, in particular when it comes to perioperative recipient management. However, very little has been published to date regarding intraoperative and immediate postoperative care in this setting. Herein, we compare perioperative events in uDCD liver recipients with those of a matched group of donation after brain death liver recipients. We demonstrate that the former group of recipients suffers significantly greater hemodynamic instability and derangements in coagulation following graft reperfusion. Based on our experience, we recommend a proactive recipient management strategy in uDCD liver transplantation that involves early use of vasopressor support; maintaining adequate intraoperative levels of red cells, platelets, and fibrinogen; and routinely administering tranexamic acid before graft reperfusion. PMID:26601629

  3. Development of operation support system for MOX fuel production line

    International Nuclear Information System (INIS)

    Plutonium Fuel Production Facility (PFPF) FBR line started production of MOX fuels for 'JOYO' MK-II in October 1988. The production campaign for 'Monju' initial core fuel followed that for 'Joyo'. Control of this line is mainly computerized to allow remote operation. According to our test run experiences the automated plant, requires the higher judgement ability of operator when a problem arises. We need the plant which can be operated by even unskilled operator, on the technical level equal to that of skilled operator. This requirement will be satisfied by introduction of new support system into applying Artificial Intelligence technology based on operating experience. Now we have developed some operation support systems taking main aim at high efficiency of production for example, the optimum operation control system the failure diagnosis system and the production planning support system. (author)

  4. ARCHITECTURE SOFTWARE SOLUTION TO SUPPORT AND DOCUMENT MANAGEMENT QUALITY SYSTEM

    Directory of Open Access Journals (Sweden)

    Milan Eric

    2010-12-01

    Full Text Available One of the basis of a series of standards JUS ISO 9000 is quality system documentation. An architecture of the quality system documentation depends on the complexity of business system. An establishment of an efficient management documentation of system of quality is of a great importance for the business system, as well as in the phase of introducing the quality system and in further stages of its improvement. The study describes the architecture and capability of software solutions to support and manage the quality system documentation in accordance with the requirements of standards ISO 9001:2001, ISO 14001:2005 HACCP etc.

  5. Decision Support System for Tele-Medical Transportation Management

    OpenAIRE

    M. Gupta; Yadav, S.; Mittal, V; Singh, P.; Saxena, P.

    2011-01-01

    In this paper, a Decision Support System for Management of Tele-Medical Transportation Services has been designed and developed. The system is developed with symbiotic approach to achieve the aim of providing the necessary Quality based Information Resources for real life interaction among Decision Members of Tele-Medical Transportation System to enable speedy decision management by scanning the future. The salient features of the System are: quick and interactive communication, instant conte...

  6. Intelligent Decision Support System for Bank Loans Risk Classification

    Institute of Scientific and Technical Information of China (English)

    杨保安; 马云飞; 俞莲

    2001-01-01

    Intelligent Decision Support System (IISS) for Bank Loans Risk Classification (BLRC), based on the way of integration Artificial Neural Network (ANN) and Expert System (ES), is proposed. According to the feature of BLRC, the key financial and non-financial factors are analyzed. Meanwhile, ES and Model Base (MB) which contain ANN are designed . The general framework,interaction and integration of the system are given. In addition, how the system realizes BLRC is elucidated in detail.

  7. Decision support database system for Hellenic Naval Personnel Management

    OpenAIRE

    Makris, Antonios K.

    1988-01-01

    The Naval Officers Personnel Management System is a very complex system especially inside the Fleet Command. Managing the system manually is neither effective nor efficient in supporting the decision makers. This thesis proposes a method to use a computer based information processing system to help decision makers in scheduling the assignment of officers to warships during the annual assignment process, as well as in other functions concerning personnel management. The thesis presents a decis...

  8. ICT Road map for supporting energy systems in smart cities

    OpenAIRE

    Sepponen, Mari; Fiès, Bruno; García Castro, Raul

    2014-01-01

    This paper introduces a road map for ICTs (Information and communication technologies) supporting planning, operation and management of energy systems in smart cities. The road map summarises different elements that form energy systems in cities and proposes research and technical development (RTD) and innovation activities for the development and innovation of ICTs for holistic design, planning and operation of energy systems. In addition, synergies with other ICT systems for smart cities ar...

  9. A Lunar Surface System Supportability Technology Development Roadmap

    Science.gov (United States)

    Oeftering, Richard C.; Struk, Peter M.; Taleghani, barmac K.

    2011-01-01

    This paper discusses the establishment of a Supportability Technology Development Roadmap as a guide for developing capabilities intended to allow NASA s Constellation program to enable a supportable, sustainable and affordable exploration of the Moon and Mars. Presented is a discussion of supportability, in terms of space facility maintenance, repair and related logistics and a comparison of how lunar outpost supportability differs from the International Space Station. Supportability lessons learned from NASA and Department of Defense experience and their impact on a future lunar outpost is discussed. A supportability concept for future missions to the Moon and Mars that involves a transition from a highly logistics dependent to a logistically independent operation is discussed. Lunar outpost supportability capability needs are summarized and a supportability technology development strategy is established. The resulting Lunar Surface Systems Supportability Strategy defines general criteria that will be used to select technologies that will enable future flight crews to act effectively to respond to problems and exploit opportunities in an environment of extreme resource scarcity and isolation. This strategy also introduces the concept of exploiting flight hardware as a supportability resource. The technology roadmap involves development of three mutually supporting technology categories, Diagnostics Test and Verification, Maintenance and Repair, and Scavenging and Recycling. The technology roadmap establishes two distinct technology types, "Embedded" and "Process" technologies, with different implementation and thus different criteria and development approaches. The supportability technology roadmap addresses the technology readiness level, and estimated development schedule for technology groups that includes down-selection decision gates that correlate with the lunar program milestones. The resulting supportability technology roadmap is intended to develop a set

  10. Software Application for Supporting the Education of Database Systems

    Science.gov (United States)

    Vágner, Anikó

    2015-01-01

    The article introduces an application which supports the education of database systems, particularly the teaching of SQL and PL/SQL in Oracle Database Management System environment. The application has two parts, one is the database schema and its content, and the other is a C# application. The schema is to administrate and store the tasks and the…

  11. The Intelligent Decision Support System Model of SARS

    Institute of Scientific and Technical Information of China (English)

    ZhouXingyu; ZhangJiang; LiuYang; XieYanqing; ZhangRan; ZhaoYang; HeZhongxiong

    2004-01-01

    Based on the intelligent decision support system, a new method was presented to defense the catastrophic infectious disease such as SARS, Bird Flu, etc.. By using All Set theory, the decision support system (DSS) model can be built to analyze the noise information and forecast the trend of the catastrophe then to give the method or policy to defend the disease. The model system is composed of four subsystems: the noise analysis subsystem, forecast and simulation subsystem, diagnosis subsystem and second recovery subsystem. They are discussed briefly in this paper. This model can be used not only for SARS but also for other paroxysmal accidences.

  12. Verification and validation of decision support Expert Systems

    International Nuclear Information System (INIS)

    Expert Systems are being designed or considered for both on-line process control and off-line decision support in the handling of hazardous materials. There are possibilities for both positive and negative impacts on chemical industry fire/explosion loss potentials. The authors review some guidelines and tools available for the verification and validation (V and V) of expert systems. Finally, they illustrate some of the points discussed by describing the development of a prototype expert system for hazardous materials classification and loss prevention engineering decision support

  13. Classification of nuclear power plant operator support systems

    International Nuclear Information System (INIS)

    The objective of this survey was to examine the general characteristics of modern nuclear power plant process monitoring/control systems and to apply developing technology (intellectual automation) in order to improve the man-machine interface. The support systems that implement each phase of the control function...information, assessment, decision-making, and implementation...were discussed, and where applicable, intellectual automation was applied to the support system. It was concluded that the application of intellectual automation, as well as other (undefined) possibilities for improving the man-machine interface, would relieve the operator of many routine activities and allow him to readily apply high potential to those poorly-formalized scenarios in which the operator's work can't be automated. It was also concluded that the development of such support systems would not be without problems, i.e. software certification, traning, and jurisdictional questions

  14. Classification of nuclear power plant operator support systems

    Energy Technology Data Exchange (ETDEWEB)

    Alpeev, A.S.

    1994-06-01

    The objective of this survey was to examine the general characteristics of modern nuclear power plant process monitoring/control systems and to apply developing technology (intellectual automation) in order to improve the man-machine interface. The support systems that implement each phase of the control function...information, assessment, decision-making, and implementation...were discussed, and where applicable, intellectual automation was applied to the support system. It was concluded that the application of intellectual automation, as well as other (undefined) possibilities for improving the man-machine interface, would relieve the operator of many routine activities and allow him to readily apply high potential to those poorly-formalized scenarios in which the operator`s work can`t be automated. It was also concluded that the development of such support systems would not be without problems, i.e. software certification, traning, and jurisdictional questions.

  15. User's manual of a support system for human reliability analysis

    International Nuclear Information System (INIS)

    Many kinds of human reliability analysis (HRA) methods have been developed. However, users are required to be skillful so as to use them, and also required complicated works such as drawing event tree (ET) and calculation of uncertainty bounds. Moreover, each method is not so complete that only one method of them is not enough to evaluate human reliability. Therefore, a personal computer (PC) based support system for HRA has been developed to execute HRA practically and efficiently. The system consists of two methods, namely, simple method and detailed one. The former uses ASEP that is a simplified THERP-technique, and combined method of OAT and HRA-ET/DeBDA is used for the latter. Users can select a suitable method for their purpose. Human error probability (HEP) data were collected and a database of them was built to use for the support system. This paper describes outline of the HRA methods, support functions and user's guide of the system. (author)

  16. Malaria elimination: moving forward with spatial decision support systems.

    Science.gov (United States)

    Kelly, Gerard C; Tanner, Marcel; Vallely, Andrew; Clements, Archie

    2012-07-01

    Operational challenges facing contemporary malaria elimination have distinct geospatial elements including the need for high-resolution location-based surveillance, targeted prevention and response interventions, and effective delivery of essential services at optimum levels of coverage. Although mapping and geographical reconnaissance (GR) has traditionally played an important role in supporting malaria control and eradication, its full potential as an applied health systems tool has not yet been fully realised. As accessibility to global positioning system (GPS), geographic information system (GIS) and mobile computing technology increases, the role of an integrated spatial decision support system (SDSS) framework for supporting the increased operational demands of malaria elimination requires further exploration, validation and application; particularly in the context of resource-poor settings. PMID:22607693

  17. LOKI: a practical modelling and support system for telepresence systems

    International Nuclear Information System (INIS)

    The use of Virtual Reality headset systems, in combination with a tele-presence ''head'' is discussed. The system is attached to a Unimate Puma robot arm and manipulated by the operator, using information gathered by the camera and auditory system, displayed via the Virtual Reality helmet. Operator commands are cross checked by using a modelling system, held on the Virtual Reality system. This system was found to supply a good sense of spacial awareness of the robot's domain. Actions which might move the robot outside its suitable operating envelope, or create a collision with the environment, were successfully blocked. This approach is seen as useful within the area of tele-operation. (author)

  18. Municipal solid waste management system: decision support through systems analysis

    OpenAIRE

    Pires, Ana Lúcia Lourenço

    2010-01-01

    The present study intends to show the development of systems analysis model applied to solid waste management system, applied into AMARSUL, a solid waste management system responsible for the management of municipal solid waste produced in Setúbal peninsula, Portugal. The model developed intended to promote sustainable decision making, covering the four columns: technical, environmental, economic and social aspects. To develop the model an intensive literature review have been conducted. T...

  19. Nanomaterials for Advanced Life Support in Advanced Life Support in Space systems

    Science.gov (United States)

    Allada, Rama Kumar; Moloney, Padraig; Yowell, Leonard

    2006-01-01

    A viewgraph presentation describing nanomaterial research at NASA Johnson Space Center with a focus on advanced life support in space systems is shown. The topics include: 1) Introduction; 2) Research and accomplishments in Carbon Dioxide Removal; 3) Research and Accomplishments in Water Purification; and 4) Next Steps

  20. Marketing Decision Making and Decision Support: Challenges and Perspectives for Successful Marketing Management Support Systems

    NARCIS (Netherlands)

    G.H. van Bruggen (Gerrit); B. Wierenga (Berend)

    2009-01-01

    textabstractMarketing management support systems (MMSS) are computer-enabled devices that help marketers to make better decisions. Marketing processes can be quite complex, involving large numbers of variables and mostly outcomes are the results of the actions of many different stakeholders (e.g., t

  1. Integrated training support system for PWR operator training simulator

    International Nuclear Information System (INIS)

    The importance of operator training using operator training simulator has been recognized intensively. Since 1986, we have been developing and providing many PWR simulators in Japan. We also have developed some training support systems connected with the simulator and the integrated training support system to improve training effect and to reduce instructor's workload. This paper describes the concept and the effect of the integrated training support system and of the following sub-systems. We have PES (Performance Enhancement System) that evaluates training performance automatically by analyzing many plant parameters and operation data. It can reduce the deviation of training performance evaluation between instructors. PEL (Parameter and Event data Logging system), that is the subset of PES, has some data-logging functions. And we also have TPES (Team Performance Enhancement System) that is used aiming to improve trainees' ability for communication between operators. Trainee can have conversation with virtual trainees that TPES plays automatically. After that, TPES automatically display some advice to be improved. RVD (Reactor coolant system Visual Display) displays the distributed hydraulic-thermal condition of the reactor coolant system in real-time graphically. It can make trainees understand the inside plant condition in more detail. These sub-systems have been used in a training center and have contributed the improvement of operator training and have gained in popularity. (author)

  2. A Automated Tool for Supporting FMEAs of Digital Systems

    Energy Technology Data Exchange (ETDEWEB)

    Yue,M.; Chu, T.-L.; Martinez-Guridi, G.; Lehner, J.

    2008-09-07

    Although designs of digital systems can be very different from each other, they typically use many of the same types of generic digital components. Determining the impacts of the failure modes of these generic components on a digital system can be used to support development of a reliability model of the system. A novel approach was proposed for such a purpose by decomposing the system into a level of the generic digital components and propagating failure modes to the system level, which generally is time-consuming and difficult to implement. To overcome the associated issues of implementing the proposed FMEA approach, an automated tool for a digital feedwater control system (DFWCS) has been developed in this study. The automated FMEA tool is in nature a simulation platform developed by using or recreating the original source code of the different module software interfaced by input and output variables that represent physical signals exchanged between modules, the system, and the controlled process. For any given failure mode, its impacts on associated signals are determined first and the variables that correspond to these signals are modified accordingly by the simulation. Criteria are also developed, as part of the simulation platform, to determine whether the system has lost its automatic control function, which is defined as a system failure in this study. The conceptual development of the automated FMEA support tool can be generalized and applied to support FMEAs for reliability assessment of complex digital systems.

  3. Ethical controversies in organ donation after circulatory death.

    Science.gov (United States)

    2013-05-01

    The persistent mismatch between the supply of and need for transplantable organs has led to efforts to increase the supply, including controlled donation after circulatory death (DCD). Controlled DCD involves organ recovery after the planned withdrawal of life-sustaining treatment and the declaration of death according to the cardiorespiratory criteria. Two central ethical issues in DCD are when organ recovery can begin and how to manage conflicts of interests. The "dead donor rule" should be maintained, and donors in cases of DCD should only be declared dead after the permanent cessation of circulatory function. Permanence is generally established by a 2- to 5-minute waiting period. Given ongoing controversy over whether the cessation must also be irreversible, physicians should not be required to participate in DCD. Because the preparation for organ recovery in DCD begins before the declaration of death, there are potential conflicts between the donor's and recipient's interests. These conflicts can be managed in a variety of ways, including informed consent and separating the various participants' roles. For example, informed consent should be sought for premortem interventions to improve organ viability, and organ procurement organization personnel and members of the transplant team should not be involved in the discontinuation of life-sustaining treatment or the declaration of death. It is also important to emphasize that potential donors in cases of DCD should receive integrated interdisciplinary palliative care, including sedation and analgesia. PMID:23629612

  4. Fuzzy rule-based support vector regression system

    Institute of Scientific and Technical Information of China (English)

    Ling WANG; Zhichun MU; Hui GUO

    2005-01-01

    In this paper,we design a fuzzy rule-based support vector regression system.The proposed system utilizes the advantages of fuzzy model and support vector regression to extract support vectors to generate fuzzy if-then rules from the training data set.Based on the first-order linear Tagaki-Sugeno (TS) model,the structure of rules is identified by the support vector regression and then the consequent parameters of rules are tuned by the global least squares method.Our model is applied to the real world regression task.The simulation results gives promising performances in terms of a set of fuzzy rules,which can be easily interpreted by humans.

  5. Support mechanisms and risk: Implications on the Nordic electricity system

    DEFF Research Database (Denmark)

    Kitzing, Lena; Ravn, Hans

    2013-01-01

    stochastic analysis for the Nordic electricity system by conducting simulations with the energy system model Balmorel and by applying the mean-standard deviation approach of modern portfolio theory to quantify risk implications of policy instruments for an exemplary offshore wind park. The analysis reveals......Investments in renewable energy projects, such as offshore wind parks, are very much dependent on financial support. The type of policy instrument chosen for such support determines investors' exposure to market risk, and thus influences which rate of return they expect to achieve. We make a...... that the two support policy schemes Feed-in Tariffs and Feed-in Premiums provide different risk-return relationships. In the investigated case, a Feed-in Premium scheme would require a 13% higher support level, because of a 6% higher exposure of investors to market risk. Our findings can help when...

  6. Visual Simulation of Microalgae Growth in Bioregenerative Life Support System

    Science.gov (United States)

    Zhao, Ming

    Bioregenerative life support system is one of the key technologies for future human deep space exploration and long-term space missions. BLSS use biological system as its core unit in combination with other physical and chemical equipments, under the proper control and manipulation by crew to complete a specific task to support life. Food production, waste treatment, oxygen and water regeneration are all conducted by higher plants or microalgae in BLSS, which is the most import characteristic different from other kinds of life support systems. Microalgae is light autotrophic micro-organisms, light undoubtedly is the most import factor which limits its growth and reproduction. Increasing or decreasing the light intensity changes the growth rate of microalgae, and then regulates the concentration of oxygen and carbon dioxide in the system. In this paper, based on the mathematical model of microalgae which grew under the different light intensity, three-dimensional visualization model was built and realized through using 3ds max, Virtools and some other three dimensional software, in order to display its change and impacting on oxygen and carbon dioxide intuitively. We changed its model structure and parameters, such as establishing closed-loop control system, light intensity, temperature and Nutrient fluid’s velocity and so on, carried out computer virtual simulation, and observed dynamic change of system with the aim of providing visualization support for system research.

  7. The design of intelligent support systems for nuclear reactor operators

    International Nuclear Information System (INIS)

    This paper identifies factors relevant to the design of intelligent support systems and their use for the provision of real-time diagnostic information. As such, it constitutes a followup to the state-of-the-art review that was previously published by Bernard and Washio on the utilization of expert systems within the nuclear industry. Some major differences between intelligent-support tools and conventional expert systems are enumerated. In summary, conventional expert systems that encode experimental knowledge in production rules are not suitable vehicle for the creation of operator support systems. The principal difficulty is the need for real-time operation. This in turn means that intelligent support systems will have knowledge bases derived from temporally accurate plant models, inference engines that permit revisions in the search process to accommodate revised data, and man-machine interfaces that do not require any human input. Such systems will be heavily instrumented, and the associated knowledge bases will require a hierarchical organization to emulate human approaches to analysis

  8. Intellectual innovative system for personalized support of tourist trips

    OpenAIRE

    Pasichnyk, V.; Savchuk, V.

    2016-01-01

    The main goal of the article is generalization of intellectual innovation project of information system ?Mobile information assistant of the tourist? (MIAT), which provide a full-featured integrated information and technological support to tourists during planning and implementation stages of his journey using a wide range of modern information technologies. About two-thirds of today's tourists use information technology to plan and support their journey, while a significant number of them...

  9. Behavior-aware decision support systems : LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Hirsch, Gary B.; Homer, Jack (Homer Consulting); Chenoweth, Brooke N.; Backus, George A.; Strip, David R.

    2007-11-01

    As Sandia National Laboratories serves its mission to provide support for the security-related interests of the United States, it is faced with considering the behavioral responses that drive problems, mitigate interventions, or lead to unintended consequences. The effort described here expands earlier works in using healthcare simulation to develop behavior-aware decision support systems. This report focuses on using qualitative choice techniques and enhancing two analysis models developed in a sister project.

  10. On the accuracy of judgmental interventions on forecasting support systems

    OpenAIRE

    Nikolopoulos, K.; Lawrence, M.; Goodwin, P; R A Fildes

    2005-01-01

    Forecasting at the Stock Keeping Unit (SKU) disaggregate level in order to support operations management has proved a very difficult task. The levels of accuracy achieved have major consequences for companies at all levels in the supply chain; errors at each stage are amplified resulting in poor service and overly high inventory levels. In most companies, the size and complexity of the forecasting task necessitates the use of Forecasting Support Systems (FSS). The present study examines month...

  11. A Conceptual Model for Group Support Systems in Local Councils

    OpenAIRE

    Harris, Joycelyn; Sun, Lily

    2008-01-01

    This paper proposes a conceptual model of a context-aware group support system (GSS) to assist local council employees to perform collaborative tasks in conjunction with inter- and intra-organisational stakeholders. Most discussions about e-government focus on the use of ICT to improve the relationship between government and citizen, not on the relationship between government and employees. This paper seeks to expose the unique culture of UK local councils and to show how a GSS could support ...

  12. Neutral Buoyancy Portable Life Support System performance study

    Science.gov (United States)

    Chang, Chi-Min; Conger, Bruce C.; Iovine, John V.

    1991-01-01

    The Neutral Buoyancy Portable Life Support System (NBPSS) has been designed to support astronaut underwater training activities associated with EVA operations. The performance of competing NBPSS configurations has been analyzed on the basis of a modified 'Metabolic Man' program. NBPSS success is dependent on the development of novel cryogen supply tank and liquid-cooling garment vaporizer. Attention is given to mass and thermal balances and the evaluation results for the vent-loop ejector and heat-exchanger designs.

  13. Supporting International Negotiation with a WWW-Based System.

    OpenAIRE

    G.E. Kersten; Noronha, S. J.

    1997-01-01

    Support for international negotiations requires integration of decision-theoretic approaches with communication facilities, and different visualization modes. In addition, negotiation support systems (NSS) should also be tailored to different cultural and educational backgrounds of their users. While there have been studies on cross-cultural negotiations involving simple game or economic models, there have been no experiments with NSS in international and cross-cultural contexts. At the same...

  14. Controlled Ecological Life Support System: Research and Development Guidelines

    Science.gov (United States)

    Mason, R. M. (Editor); Carden, J. L. (Editor)

    1982-01-01

    Results of a workshop designed to provide a base for initiating a program of research and development of controlled ecological life support systems (CELSS) are summarized. Included are an evaluation of a ground based manned demonstration as a milestone in CELSS development, and a discussion of development requirements for a successful ground based CELSS demonstration. Research recommendations are presented concerning the following topics: nutrition and food processing, food production, waste processing, systems engineering and modelling, and ecology-systems safety.

  15. The Heureka forestry decision support system : an overview

    OpenAIRE

    Wikström, Peder; Edenius, Lars; Elfving, Björn; Eriksson, Ljusk Ola; Lämås, Tomas; Sonesson, Johan; Öhman, Karin; Wallerman, Jörgen; Waller, Carina; Klintebäck, Fredrik

    2011-01-01

    Mathematical programming and computers have been used for several decades to solve complex and long term forest management planning problems. The ever increasing demand on the forest ecosystem to produce wood and other goods and services poses a corresponding demand on a forest decision support system. As a response to meet new requirements the development of the Heureka system was initiated at SLU in 2002 and a first version of the system was released in 2009. Based on a common kernel, a num...

  16. Decision support system for containment and release management

    International Nuclear Information System (INIS)

    The Containment and Release Management project was carried out within the Reinforced Concerted Action Programme for Accident Management Support and partly financed by the European Union. In this report a prototype of an accident management support system is presented. The support system integrates several concepts from accident management research, like safety objective trees, severe accident phenomena, calculation models and an emergency response data system. These concepts are provided by the prototype in such a way that the decision making process of accident management is supported. The prototype application is demonstrated by process data taken from a severe accident scenario for a pressurized water reactor (PWR) that was simulated with the thermohydraulic computer program MAAP. The prototype was derived from a decision support framework based on a decision theory. For established and innovative concepts from accident management research it is pointed out in which way these concepts can support accident management and how these concepts can be integrated. This approach is generic in two ways; it applies to both pressurized and boiling water reactors and it applies to both in vessel management and containment and release management. The prototype application was developed in Multimedia Toolbox 3.0 and requires at least a 386 PC with 4 MB memory, 6 MB free disk space and MS Windows 3.1. (orig.)

  17. Simulating advanced life support systems to test integrated control approaches

    Science.gov (United States)

    Kortenkamp, D.; Bell, S.

    Simulations allow for testing of life support control approaches before hardware is designed and built. Simulations also allow for the safe exploration of alternative control strategies during life support operation. As such, they are an important component of any life support research program and testbed. This paper describes a specific advanced life support simulation being created at NASA Johnson Space Center. It is a discrete-event simulation that is dynamic and stochastic. It simulates all major components of an advanced life support system, including crew (with variable ages, weights and genders), biomass production (with scalable plantings of ten different crops), water recovery, air revitalization, food processing, solid waste recycling and energy production. Each component is modeled as a producer of certain resources and a consumer of certain resources. The control system must monitor (via sensors) and control (via actuators) the flow of resources throughout the system to provide life support functionality. The simulation is written in an object-oriented paradigm that makes it portable, extensible and reconfigurable.

  18. A theoretical foundation for building Knowledge-work Support Systems

    CERN Document Server

    Laha, Arijit

    2009-01-01

    In this paper we propose a novel approach aimed at building a new class of information system platforms which we call the "Knowledge-work Support Systems" or KwSS. KwSS can play a significant role in enhancing the IS support for knowledge management processes, including those customarily identified as less amenable to IS support. In our approach we try to enhance basic functionalities provided by the computer-based information systems, namely, that of improving the efficiency of the knowledge workers in accessing, processing and creating useful information. The improvement, along with proper focus on cultural, social and other aspects of the knowledge management processes, can enhance the workers' efficiency significantly in performing high quality knowledge works. In order to build the proposed approach, we develop several new concepts. The approach analyzes the information availability and usage from the knowledge workers and their works' perspectives and consequently brings forth more transparency in vario...

  19. Analysis of circulatory mitochondrial DNA level after cardiac surgery with cardiopulmonary bypass and potential prognostic implications.

    Science.gov (United States)

    Qin, Chaoyi; Gu, Jun; Qian, Hong; Meng, Wei

    2016-01-01

    Our research letter found that circulatory mtDNA level increased after the end of CPB and positive correlations between mtDNA and peak CRP level, peak BNP level, and peak PCT level, which revealed the prognostic role of perioperative circulatory mtDNA level in patients who underwent cardiopulmonary bypass. PMID:27316503

  20. Sizable variations in circulatory disease mortality by region and country of birth in six European countries.

    NARCIS (Netherlands)

    Rafnsson, S.B.; Bhopal, R.S.; Agyemang, C.; Fagot-Campagna, A.; Harding, S.; Hammar, N.; Hedlund, E.; Juel, K.; Primatesta, P.; Rosato, M.; Rey, G.; Wild, S.H.; Mackenbach, J.P.; Stirbu, I.; Kunst, A.E.

    2013-01-01

    Background: Circulatory disease mortality inequalities by country of birth (COB) have been demonstrated for some EU countries but pan-European analyses are lacking. We examine inequalities in circulatory mortality by geographical region/COB for six EU countries. Methods: We obtained national death a

  1. Development of BWR operator training simulator and training support systems

    International Nuclear Information System (INIS)

    This paper describes a BWR operator training simulator and training support systems that have been developed with the aim of providing support throughout operator training. The operator training simulator is needed in order to improve simulation fidelity and enlarge simulation scope. A 3-dimensional reactor core model has been developed in order to improve the understanding of operators respecting neutronics through realistic training. A severe accident model has been developed for training operators and technical support center teams respecting plant operation and for studying various phenomena. The severe accident is simulated by connecting the physical parameters continuously from the conventional model to the severe accident model. An emergency procedure guideline support system is adopted in order to improve efficiency of operation training for emergencies, since the emergency operation procedures are complicated and based on multiple parameter conditions. The operator training support system is also introduced so as to help training instructors to evaluate the operation and to give instructions to operators to improve operational accuracy. An instructor's burden is eased by automatically evaluating the operation errors based on signals of a simulator. The effects of these systems are evaluated and found to be effective in an actual training center and in engineers' examinations. (author)

  2. Strategy generator in computerized accident management support system

    International Nuclear Information System (INIS)

    An increased interest for research in the field of accident management of nuclear power plants can be noted. Several international programmes have been started in order to be able to understand the basic physical and chemical phenomena in accident conditions. A feasibility study has shown that it would be possible to design and develop a computerized support system for plant staff in accident situations. To achieve this goal the Halden Project has initiated a research programme on Computerized Accident Management Support (CAMS project). The aim is to utilize the capabilities of computerized tools to support the plant staff during the various accident stages. The system will include identification of the accident state, assessment of the future development of the accident and planning of accident mitigation strategies. A prototype is developed to support operators and the Technical Support Centre in decision making during serious accidents in nuclear power plants. A rule based system has been built to take care of the strategy generation. This system assists plant personnel in planning control proposals and mitigation strategies from normal operation to severe accident conditions. The idea of a safety objective tree and knowledge from the emergency procedures have been used. Future prediction requires good state identification of the plant status and some knowledge about the history of some critical variables. The information needs to be validated as well. Accurate calculations in simulators and a large database including all important information from the plant will help the strategy planning. (orig.). (40 refs., 20 figs.)

  3. Sustainability of life support systems in emergency situations

    Directory of Open Access Journals (Sweden)

    Volkov Andrey Anatol’evich

    2014-04-01

    Full Text Available Modern humanity development is impossible without scientific and technological progress, energy, industry, transport. Despite the fact that industrialization and the constant increase of production capacity have helped people to expand their limits significantly, we should not forget that today our dependence on the established infrastructure is steadily increasing. It is most vivid in case of natural hazards or disasters, which lead to disruption of normal living conditions. Any of these negative phenomena is called "emergency situation". However, the occurrence of emergency situations in life support systems leads to the following negative consequences: disorganization of life support systems functioning on the object, local, regional, national levels; exclusion or complete destruction life support systems; partial or complete reduction of the opportunities for ensuring the needs of the population; danger to life and health of the population. Despite the considerable number of scientific publications, many theoretical and methodological aspects of creating mechanisms and resistance patterns of objects and systems require further investigation that is due to: the possibility of emergency situations doesn’t decrease; acceleration of scientific and technical progress; existing threat of war together with the continuous improvement of weapons; threat of terrorist acts, etc. The authors present a research of the opportunity to construct a sustainability model of life support systems under different emergency situations in respect of modern current trends in the development of information-analytical systems and principles of systems engineering approach. The development of a general stability model, in that case, must consider common sequence of actions, ranging from signs of disaster to the recommendations for eliminating its consequences for life support systems, and the issues of effective interaction between individual subsystems involved in

  4. A health examination system integrated with clinical decision support system.

    Science.gov (United States)

    Kuo, Kuan-Liang; Fuh, Chiou-Shann

    2010-10-01

    Health examinations play a key role in preventive medicine. We propose a health examination system named Health Examination Automatic Logic System (HEALS) to assist clinical workers in improving the total quality of health examinations. Quality of automated inference is confirmed by the zero inference error where during 6 months and 14,773 cases. Automated inference time is less than one second per case in contrast to 2 to 5 min for physicians. The most significant result of efficiency evaluation is that 3,494 of 4,356 (80.2%) cases take less than 3 min per case for producing a report summary. In the evaluation of effectiveness, novice physicians got 18% improvement in making decisions with the assistance of our system. We conclude that a health examination system with a clinical decision system can greatly reduce the mundane burden on clinical workers and markedly improve the quality and efficiency of health examination tasks. PMID:20703626

  5. ERP System Audit a Control Support For Knowledge Management

    Directory of Open Access Journals (Sweden)

    Traian SURCEL

    2008-01-01

    Full Text Available The ERP system supports most of the business system that maintains in a single database the data needed for a variety of business functions such as Manufacturing, SCM, Financials, Projects, Human Resources and CRM; the audit of this systems is necessary in order to give reasonable assurance to the company on its core system. Obtained evidence evaluation can ensure whether the organization's IT&C system safeguard assets, maintains data integrity, and is operating effectively and efficiently to achieve the organization's goals or objectives. The audit process respecting the methodology based on: gathering information and plan; obtaining an understanding of internal controls; performing test of controls and substantive tests, develop a control support on quality of flow of information and knowledge from formal perspective, for Knowledge Management in large enterprises.

  6. Pricing Decision Support System for Generation Companies in Electricity Market

    Institute of Scientific and Technical Information of China (English)

    FangDebin; WangXianjia

    2005-01-01

    In order to meet the requirement of separating power plants from power network and that of the competition based power transaction in power market, the pricing decision support system for generation companies (GCPDSS) is built in electricity market. This paper introduces the conception of intelligent decision support system (IDSS) and puts emphasis on the systematical structural framework,work process, design principal, and fundamental function of GCPDSS. The system has the module to analyze the cost, to forecast the demand of power, to construct the pricing strategies, to manage the pricing risk, and to dispatch giving the pricing strategies.The case study illustrates that the friendly window-based user interface of the system enables the user to take full advantage of the capabilities of the system in order to make effective real-time decisions.

  7. Computational intelligence for decision support in cyber-physical systems

    CERN Document Server

    Ali, A; Riaz, Zahid

    2014-01-01

    This book is dedicated to applied computational intelligence and soft computing techniques with special reference to decision support in Cyber Physical Systems (CPS), where the physical as well as the communication segment of the networked entities interact with each other. The joint dynamics of such systems result in a complex combination of computers, software, networks and physical processes all combined to establish a process flow at system level. This volume provides the audience with an in-depth vision about how to ensure dependability, safety, security and efficiency in real time by making use of computational intelligence in various CPS applications ranging from the nano-world to large scale wide area systems of systems. Key application areas include healthcare, transportation, energy, process control and robotics where intelligent decision support has key significance in establishing dynamic, ever-changing and high confidence future technologies. A recommended text for graduate students and researche...

  8. Support mechanisms and risk: Implications on the Nordic electricity system

    DEFF Research Database (Denmark)

    Kitzing, Lena; Ravn, Hans

    2013-01-01

    Investments in renewable energy projects, such as offshore wind parks, are very much dependent on financial support. The type of policy instrument chosen for such support determines investors' exposure to market risk, and thus influences which rate of return they expect to achieve. We make a...... stochastic analysis for the Nordic electricity system by conducting simulations with the energy system model Balmorel and by applying the mean-standard deviation approach of modern portfolio theory to quantify risk implications of policy instruments for an exemplary offshore wind park. The analysis reveals...

  9. Research of Agile Supply Chain Management Decision Support System

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Agile Supply Chain Management (ASCM) is an important topic and has received much attention recently.ASCM is a new management technology.Agile Supply Chain Management Decision Support System (ASCM-DSS) is presented.Firstly, agile supply chain management technology is introduced.Secondly a decision support system for agile supply chain management is proposed.Then, the implementation of ASCM-DSS in enterprise is discussed.Finally, a fuzzy intelligence decision-making process in Shanghai Turbine Generator Company (STGC) is described in detail.

  10. An information system supporting design for reliability and maintenance

    International Nuclear Information System (INIS)

    EDF is currently developing a methodology to integrate availability, operating experience and maintenance in the design of power plants. This involves studies that depend closely on the results and assumptions of each other about the reliability and operations of the plant. Therefore a support information system must be carefully designed. Concurrently with development of the methodology, a research oriented information system was designed and built. It is based on the database model of a logistic support repository that we tailored to our needs. (K.A.)

  11. Novel applications of intuitionistic fuzzy digraphs in decision support systems.

    Science.gov (United States)

    Akram, Muhammad; Ashraf, Ather; Sarwar, Mansoor

    2014-01-01

    Many problems of practical interest can be modeled and solved by using graph algorithms. In general, graph theory has a wide range of applications in diverse fields. In this paper, the intuitionistic fuzzy organizational and neural network models, intuitionistic fuzzy neurons in medical diagnosis, intuitionistic fuzzy digraphs in vulnerability assessment of gas pipeline networks, and intuitionistic fuzzy digraphs in travel time are presented as examples of intuitionistic fuzzy digraphs in decision support system. We have also designed and implemented the algorithms for these decision support systems. PMID:25045752

  12. Inspection support system at the Rokkasho Enrichment Plant (REP)

    International Nuclear Information System (INIS)

    At Rokkasho Enrichment Plant (REP), location map, itemized list and inspection seals information had been prepared for inventory and inventory change verification by paper basis. Therefore lots of documents were needed at the job site, and time was required for information retrieval. In order to provide efficient inspection, REP has developed and implemented inspection support system based on mobile computer and Microsoft Access, which can provide all necessary information retrieval for the inspection in timely. This paper describes outline of inspection support system. (author)

  13. An information system supporting design for reliability and maintenance

    Energy Technology Data Exchange (ETDEWEB)

    Rit, J.F.; Beraud, M.T

    1997-12-31

    EDF is currently developing a methodology to integrate availability, operating experience and maintenance in the design of power plants. This involves studies that depend closely on the results and assumptions of each other about the reliability and operations of the plant. Therefore a support information system must be carefully designed. Concurrently with development of the methodology, a research oriented information system was designed and built. It is based on the database model of a logistic support repository that we tailored to our needs. (K.A.) 10 refs.

  14. Data warehouse based decision support system in nuclear power plants

    International Nuclear Information System (INIS)

    Safety is an important element in business decision making processes in nuclear power plants. Information about component reliability, structures and systems, data recorded during the nuclear power plant's operation and outage periods, as well as experiences from other power plants are located in different database systems throughout the power plant. It would be possible to create a decision support system which would collect data, transform it into a standardized form and store it in a single location in a format more suitable for analyses and knowledge discovery. This single location where the data would be stored would be a data warehouse. Such data warehouse based decision support system could help make decision making processes more efficient by providing more information about business processes and predicting possible consequences of different decisions. Two main functionalities in this decision support system would be an OLAP (On Line Analytical Processing) and a data mining system. An OLAP system would enable the users to perform fast, simple and efficient multidimensional analysis of existing data and identify trends. Data mining techniques and algorithms would help discover new, previously unknown information from the data as well as hidden dependencies between various parameters. Data mining would also enable analysts to create relevant prediction models that could predict behaviour of different systems during operation and inspection results during outages. The basic characteristics and theoretical foundations of such decision support system are described and the reasons for choosing a data warehouse as the underlying structure are explained. The article analyzes obvious business benefits of such system as well as potential uses of OLAP and data mining technologies. Possible implementation methodologies and problems that may arise, especially in the field of data integration, are discussed and analyzed.(author)

  15. Proposed Support Decision Making System for the Remote Monitoring of Commercial and Residencial Central Alarm Systems

    OpenAIRE

    Alex Luiz de Sousa; André Bittencourt Leal; Ricardo Ferreira Martins; Claudio Cesar de Sá

    2011-01-01

    This article proposes a system to support decision making for the remote monitoring of commercial and residencial central alarm systems. The basis of the system is modeled with deterministic finite automata and the support for decision-making uses of induction of decision trees and case-based reasoning. A prototype system was developed for validation and testing.

  16. Proposed Support Decision Making System for the Remote Monitoring of Commercial and Residencial Central Alarm Systems

    Directory of Open Access Journals (Sweden)

    Alex Luiz de Sousa

    2011-12-01

    Full Text Available This article proposes a system to support decision making for the remote monitoring of commercial and residencial central alarm systems. The basis of the system is modeled with deterministic finite automata and the support for decision-making uses of induction of decision trees and case-based reasoning. A prototype system was developed for validation and testing.

  17. Sizable variations in circulatory disease mortality by region and country of birth in six European countries

    DEFF Research Database (Denmark)

    Rafnsson, Snorri B; Bhopal, Raj S; Agyemang, Charles;

    2013-01-01

    . RESULTS: South Asians in Denmark, England and Wales and France experienced excess circulatory disease mortality (MRRs 1.37-1.91). Similar results were seen for Eastern Europeans in these countries as well as in Sweden (MRRs 1.05-1.51), for those of Middle Eastern origin in Denmark (MRR = 1.49) and France......BACKGROUND: Circulatory disease mortality inequalities by country of birth (COB) have been demonstrated for some EU countries but pan-European analyses are lacking. We examine inequalities in circulatory mortality by geographical region/COB for six EU countries. METHODS: We obtained national death...... sizes. The pattern for IHD mortality was similar to that for circulatory disease mortality. Two- to three-fold excess cerebrovascular disease mortality was found for several foreign-born groups compared with the local-born populations in some countries. CONCLUSIONS: Circulatory disease mortality varies...

  18. GEOGRAPHICAL INFORMATION SYSTEM, DECISION SUPPORT SYSTEMS, AND URBAN STORMWATER MANAGEMENT

    Science.gov (United States)

    The full report reviews the application of Geographic Inforamtion System (GIS) technology to the field of urban stormwater modeling. The GIS literature is reviewed in the context of its use as a spatial database for urban stormwater modeling, integration of GIS and hydroloic time...

  19. Refurbishment of the IEAR1 primary coolant system piping supports

    Energy Technology Data Exchange (ETDEWEB)

    Fainer, Gerson; Faloppa, Altair A.; Oliveira, Carlos A. de; Mattar Neto, Miguel, E-mail: gfainer@ipen.br, E-mail: afaloppa@ipen.br, E-mail: calberto@ipen.br, E-mail: mmattar@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    A partial replacement of the IEA-R1 piping system was concluded in 2014. This paper presents the study and the structural analysis of the IEA-R1 primary circuit piping supports, considering all the changes involved in the replacement. The IEA-R1 is a nuclear reactor for research purposes designed by Babcox-Willcox that is operated by IPEN since 1957. The reactor life management and modernization program is being conducted for the last two decades and already resulted in a series of changes, especially on the reactor coolant system. This set of components, divided in primary and secondary circuit, is responsible for the circulation of water into the core to remove heat. In the ageing management program that includes regular inspection, some degradation was observed in the primary piping system. As result, the renewing of the piping system was conducted in 2014. Moreover the poor condition of some original piping supports gave rise to the refurbishment of all piping supports. The aim of the present work is to review the design of the primary system piping supports taking into account the current conditions after the changes and refurbishment. (author)

  20. Clinical decision support for perioperative information management systems.

    Science.gov (United States)

    Wanderer, Jonathan P; Ehrenfeld, Jesse M

    2013-12-01

    Clinical decision support (CDS) systems are being used to optimize the increasingly complex care that our health care system delivers. These systems have become increasingly important in the delivery of perioperative care for patients undergoing cardiac, thoracic, and vascular procedures. The adoption of perioperative information management systems (PIMS) has allowed these technologies to enter the operating room and support the clinical work flow of anesthesiologists and operational processes. Constructing effective CDS systems necessitates an understanding of operative work flow and technical considerations as well as achieving integration with existing information systems. In this review, we describe published examples of CDS for PIMS, including support for cardiopulmonary bypass separation physiological alarms, β-blocker guideline adherence, enhanced revenue capture for arterial line placement, and detection of hemodynamic monitoring gaps. Although these and other areas are amenable to CDS systems, the challenges of latency and data reliability represent fundamental limitations on the potential application of these tools to specific types of clinical issues. Ultimately, we expect that CDS will remain an important tool in our efforts to optimize the quality of care delivered. PMID:23690340

  1. Alternate design of ITER cryostat skirt support system

    International Nuclear Information System (INIS)

    The skirt support of ITER cryostat is a support system which takes all the load of cryostat cylinder and dome during normal and operational condition. The present design of skirt support has full penetration weld joints at the bottom (shell to horizontal plate joint). To fulfill the requirements of tolerances and control the welding distortions, we have proposed to change the full penetration weld into fillet weld. A detail calculation is done to check the feasibility and structural impact due to proposed design. The calculations provide the size requirements of fillet weld. To verify the structural integrity during most severe load case, finite element analysis (FEA) has been done in line with ASME section VIII division 2. By FEA 'Plastic Collapse' and 'Local Failure' modes has been assessed. 5° sector of skirt clamp has been modeled in CATIA V5 R21 and used in FEA. Fillet weld at shell to horizontal plate joint has been modeled and symmetry boundary condition at ± 2.5° applied. 'Elastic Plastic Analysis' has been performed for the most severe loading case i.e. Category IV loading. The alternate design of Cryostat Skirt support system has been found safe by analysis against Plastic collapse and Local Failure Modes with load proportionality factor 2.3. Alternate design of Cryostat skirt support system has been done and validated by FEA. As per alternate design, the proposal of fillet weld has been implemented in manufacturing. (author)

  2. Optimization of support concepts for piping systems using evolutionary algorithms

    International Nuclear Information System (INIS)

    For the design or backfitting of piping systems a support concept has to be found so that for all loading conditions the stresses and loads on the components, fittings and connections are as low as possible. The problems result from the fact that for different load cases different support concepts are optimal. The load from thermal strains need soft supports in order to avoid constraints, while for seismic loads the optimum support concept needs rigid fittings. Thus, the resulting concept is always a compromise for the load transfer of expected load cases. Based on the example of a bypass cooling loop in a nuclear power plant the authors show that genetic algorithms are adequate tools to solve the optimization problem.

  3. Space Station Environmental Control/Life Support System engineering

    Science.gov (United States)

    Miller, C. W.; Heppner, D. B.

    1985-01-01

    The present paper is concerned with a systems engineering study which has provided an understanding of the overall Space Station ECLSS (Environmental Control and Life Support System). ECLSS/functional partitioning is considered along with function criticality, technology alternatives, a technology description, single thread systems, Space Station architectures, ECLSS distribution, mechanical schematics per space station, and Space Station ECLSS characteristics. Attention is given to trade studies and system synergism. The Space Station functional description had been defined by NASA. The ECLSS will utilize technologies which embody regenerative concepts to minimize the use of expendables.

  4. Experience with the BEACON core monitoring and support system

    International Nuclear Information System (INIS)

    Westinghouse has developed an advanced operational core monitoring and support package called BEACON which uses current instrumentation in conjunction with a fully analytical methodology for on-line generation of 3-D power distributions. The system provides core monitoring, core measurement reduction, core analysis and follow, and core predictions. The heart of the system is a very fast and accurate three dimensional nodal code which is used for core monitoring, simulation, and predictions. The system has been installed at several sites, and extensive feedback has been obtained. A number of tests have been performed for the validation of the BEACON system for core monitoring and core predictions

  5. Methodology and Supporting Toolset Advancing Embedded Systems Quality

    DEFF Research Database (Denmark)

    Berger, Michael Stübert; Soler, José; Brewka, Lukasz Jerzy; Tsagkaropoulos, M.; Leclerc, Y.; Olma, C.

    Software quality is of primary importance in the development of embedded systems that are often used in safety-critical applications. Moreover, as the life cycle of embedded products becomes increasingly tighter, productivity and quality are simultaneously required and closely interrelated towards...... delivering competitive products. In this context, the MODUS (Methodology and supporting toolset advancing embedded systems quality) project aims to provide a pragmatic and viable solution that will allow SMEs to substantially improve their positioning in the embedded-systems development market. This paper...... will describe the MODUS project with focus on the technical methodologies that will be developed advancing embedded system quality....

  6. Computerised decision support systems for healthcare professionals: an interpretative review

    Directory of Open Access Journals (Sweden)

    Kathrin Cresswell

    2013-03-01

    Full Text Available Purpose Computerised decision support systems are designed to support clinicians in making decisions and thereby enhance the quality and safety of care. We aimed to undertake an interpretative review of the empirical evidence on computerised decision support systems, their contexts of use, and summarise evidence on the effectiveness of these tools and insights into how these can be successfully implemented and adopted.Methods We systematically searched the empirical literature to identify systematic literature reviews on computerised decision support applications and their impact on the quality and safety of healthcare delivery over a 13-year period (1997–2010. The databases searched included: MEDLINE, EMBASE, The Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, The Cochrane Central Register of Controlled Trials, The Cochrane Methodology Register, The Health Technology Assessment Database, and The National Health Service (NHS Economic Evaluation Database. To be eligible for inclusion, systematic reviews needed to address computerised decision support systems, and at least one of the following: impact on safety; quality; or organisational, implementation or adoption considerations.Results Our searches yielded 121 systematic reviews relating to eHealth, of which we identified 41 as investigating computerised decision support systems. These indicated that, whilst there was a lack of investigating potential risks, such tools can result in improvements in practitioner performance in the promotion of preventive care and guideline adherence, particularly if specific information is available in real time and systems are effectively integrated into clinical workflows. However, the evidence regarding impact on patient outcomes was less clear-cut with reviews finding either no, inconsistent or modest benefits.Conclusions Whilst the potential of clinical decision support systems in improving, in particular

  7. Mechanical circulatory assist devices: a primer for critical care and emergency physicians.

    Science.gov (United States)

    Sen, Ayan; Larson, Joel S; Kashani, Kianoush B; Libricz, Stacy L; Patel, Bhavesh M; Guru, Pramod K; Alwardt, Cory M; Pajaro, Octavio; Farmer, J Christopher

    2016-01-01

    Mechanical circulatory assist devices are now commonly used in the treatment of severe heart failure as bridges to cardiac transplant, as destination therapy for patients who are not transplant candidates, and as bridges to recovery and "decision-making". These devices, which can be used to support the left or right ventricles or both, restore circulation to the tissues, thereby improving organ function. Left ventricular assist devices (LVADs) are the most common support devices. To care for patients with these devices, health care providers in emergency departments (EDs) and intensive care units (ICUs) need to understand the physiology of the devices, the vocabulary of mechanical support, the types of complications patients may have, diagnostic techniques, and decision-making regarding treatment. Patients with LVADs who come to the ED or are admitted to the ICU usually have nonspecific clinical symptoms, most commonly shortness of breath, hypotension, anemia, chest pain, syncope, hemoptysis, gastrointestinal bleeding, jaundice, fever, oliguria and hematuria, altered mental status, headache, seizure, and back pain. Other patients are seen for cardiac arrest, psychiatric issues, sequelae of noncardiac surgery, and trauma. Although most patients have LVADs, some may have biventricular support devices or total artificial hearts. Involving a team of cardiac surgeons, perfusion experts, and heart-failure physicians, as well as ED and ICU physicians and nurses, is critical for managing treatment for these patients and for successful outcomes. This review is designed for critical care providers who may be the first to see these patients in the ED or ICU. PMID:27342573

  8. EXODUS: Integrating intelligent systems for launch operations support

    Science.gov (United States)

    Adler, Richard M.; Cottman, Bruce H.

    1991-01-01

    Kennedy Space Center (KSC) is developing knowledge-based systems to automate critical operations functions for the space shuttle fleet. Intelligent systems will monitor vehicle and ground support subsystems for anomalies, assist in isolating and managing faults, and plan and schedule shuttle operations activities. These applications are being developed independently of one another, using different representation schemes, reasoning and control models, and hardware platforms. KSC has recently initiated the EXODUS project to integrate these stand alone applications into a unified, coordinated intelligent operations support system. EXODUS will be constructed using SOCIAL, a tool for developing distributed intelligent systems. EXODUS, SOCIAL, and initial prototyping efforts using SOCIAL to integrate and coordinate selected EXODUS applications are described.

  9. Separations technologies supporting the development of a deployable ATW system

    International Nuclear Information System (INIS)

    A program has been initiated for the purpose of developing the chemical separations technologies necessary to support a large Accelerator Transmutation of Waste (ATW) system capable of dealing with the projected inventory of spent fuel from the commercial nuclear power stations in the United States. The first several years of the program will be directed toward an elucidation of related technical issues and to the establishment, by means of comprehensive trade studies, of an optimum configuration of the elements of the chemical processing infrastructure required for support of the total ATW system. By adopting this sort of disciplined systems engineering approach, it is expected that development and demonstration costs can be minimized and that it will be possible to deploy an ATW system that is an environmentally sound and economically viable venture

  10. Web system to support analysis of the Tile Calorimeter commissioning

    International Nuclear Information System (INIS)

    This article describes the set of computer systems that support the data analysis and quality control during the Tile Calorimeter commissioning phase. The Tile Commissioning Web System (TCWS) encapsulates the steps to retrieve information, execute programs, access the outcomes, register statements and verify the equipment status. TCWS integrates different applications, each one presenting a particular view of the commissioning process. The TileComm Analysis stores plots and analysis results, provides equipment-oriented visualization, collects information regarding the equipment performance, and outlines its status in each test. The Timeline application provides the equipment status history in a chronological way. The Web Interface for Shifters supports monitoring tasks by managing test parameters, graphical views of the detector's performance, and information status of all equipment that was used in each test. The DCS Web System provides a standard way to verify the behaviour of power sources and the cooling system

  11. Development of lung cancer CT screening operating support system

    Science.gov (United States)

    Ishigaki, Rikuta; Hanai, Kozou; Suzuki, Masahiro; Kawata, Yoshiki; Niki, Noboru; Eguchi, Kenji; Kakinuma, Ryutaro; Moriyama, Noriyuki

    2009-02-01

    In Japan, lung cancer death ranks first among men and third among women. Lung cancer death is increasing yearly, thus early detection and treatment are needed. For this reason, CT screening for lung cancer has been introduced. The CT screening services are roughly divided into three sections: office, radiology and diagnosis sections. These operations have been performed through paper-based or a combination of paper-based and an existing electronic health recording system. This paper describes an operating support system for lung cancer CT screening in order to make the screening services efficient. This operating support system is developed on the basis of 1) analysis of operating processes, 2) digitalization of operating information, and 3) visualization of operating information. The utilization of the system is evaluated through an actual application and users' survey questionnaire obtained from CT screening centers.

  12. Study on the Support Systems for Corporate Governance

    Directory of Open Access Journals (Sweden)

    Claudiu BRANDAS

    2011-01-01

    Full Text Available The problems generated by the information asymmetry within the agency relationships at corporation level, governments and capital markets led to a higher necessity for corporate governance (CG. The information system of corporate governance is a very complex one, which involves a series of actors, decision-making and transactional processes, technologies, procedures and good practice codes. In order to ensure the efficiency and efficacy of corporate governance as a premise for increasing company’s performance and position consolidation for the company on the capital market, it is necessary to analyze the way information technology could contribute to this undertaking. The purpose of this study is to analyze the architecture of the corporate governance systems and to identify and classify the systems and technologies involved in ensuring CG support in order to underlie the basis for developing a conceptual model for a hybrid and collaborative support system for corporate governance.

  13. Food chain data customization for decision support systems in Austria

    International Nuclear Information System (INIS)

    In the case of a nuclear accident in Europe the integral decision support system R.O.D.O.S. ( real-time on-line decision support system for off-site emergency management) supplies comprehensive information on the present and future radiological situation, and the consequences of measures to protect the population. These data comprise mainly map information such as population distribution, rivers, roads, vegetation areas and production data of various food products. This work concentrates on the customization of the data for the food chain and dose module for terrestrial pathways. During the last fifteen years two different codes have been used in Austria for support during accidents with radioactive releases: O.E.C.O.S.Y.S. and R.O.D.O.S.. Adaptations and improvements have been performed to give better tools, they are detailed in this paper. (N.C.)

  14. Technical data tracking and the Licensing Support System (LSS)

    International Nuclear Information System (INIS)

    The Department of Energy/Office of Civilian Radioactive Waste Management (DOE/OCRWM) is responsible for the characterization of Yucca Mountain, Nevada, to determine if it is a suitable site for the location of the first high-level radioactive waste repository. Site Characterization involves extensive scientific investigations and engineering analyses. The DOE/OCRWM must ensure that traceability is retained between data collected in the course of site characterization and the conclusions based upon that data. The DOE/OCRWM must also identify and provide access to the data it generates in a timely manner to facilitate the licensing process. Finally, the DOE/OCRWM must submit the data or its description and access location to the Licensing Support System for use in support of the license application and supporting documentation. This paper reports that the Automated Technical Data Tracking system and its associated Technical Data Information Form meet those needs and provide key links in the licensing process

  15. Marketing Decision Making and Decision Support: Challenges and Perspectives for Successful Marketing Management Support Systems

    OpenAIRE

    Bruggen, Gerrit; Wierenga, Berend

    2009-01-01

    textabstractMarketing management support systems (MMSS) are computer-enabled devices that help marketers to make better decisions. Marketing processes can be quite complex, involving large numbers of variables and mostly outcomes are the results of the actions of many different stakeholders (e.g., the company itself, its customers, its competitors). Moreover, a large number of interdependencies exist between the relevant variables and the outcomes of marketing actions are subject to major unc...

  16. Field Support System (FS-AID) and Working Capital Fund Tracking System (WCF-TS)

    Data.gov (United States)

    US Agency for International Development — The Field Support System (FS-AID) and Working Capital Fund Tracking System (WCF-TS) are two modules of a single data management system that share common tables and...

  17. Study on Decision Support System of Employee Turnover Risk Management

    OpenAIRE

    Xiang Liu

    2009-01-01

    Employee turnover risk is becoming an important aspect that influences the stability and development of enterprises in the times of knowledge economy. After analyzing the factors of employee turnover risk which would threaten enterprise production and operation activities, a decision support system in this field will be proposed, and it is realized by message processing mechanism, software combination technology and system integration. Also, the corresponding management strategies were set up...

  18. SUWAMAS, a decision support model for sustainable waste management systems

    OpenAIRE

    Marquez Oropeza, Eduardo

    2006-01-01

    SUWAMAS is a decision support model designed to deliver sustainable waste management strategies. Recommended strategies promote economic growth and social cohesion without impairing environmental quality. These strategies consider the integrated product policy approach and European waste management strategic drivers. SUWAMAS is designed to minimise unsustainable production and consumption patterns through the life cycle of the product system. The product system consists of recovery and dispos...

  19. Controlled ecological life support system breadboard project, 1988

    Science.gov (United States)

    Knott, W. M.

    1990-01-01

    The Closed Ecological Life Support System (CELSS) Breadboard Project, NASA's effort to develop the technology required to produce a functioning bioregenerative system, is discussed. The different phases of the project and its current status are described. The relationship between the project components are shown, and major project activities for fiscal years 1989 to 1993 are listed. The Biomass Production Chamber (BPC) became operational and tests of wheat as a single crop are nearing completion.

  20. Controlled Ecological Life Support System Breadboard Project - 1988

    Science.gov (United States)

    Knott, W. M.

    1989-01-01

    The Controlled Ecological Life Support System (CELSS) Breadboard Project, NASA's effort to develop the technology required to produce a functioning bioregenerative system, is discussed. The different phases of the project and its current status are described. The relationship between the project components are shown, and major project activities for fiscal years 1989-1993 are listed. The biomass production chamber to be used by the project is described.