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Sample records for chinese medicinal materials

  1. DNA based identification of medicinal materials in Chinese patent medicines

    Science.gov (United States)

    Chen, Rong; Dong, Juan; Cui, Xin; Wang, Wei; Yasmeen, Afshan; Deng, Yun; Zeng, Xiaomao; Tang, Zhuo

    2012-12-01

    Chinese patent medicines (CPM) are highly processed and easy to use Traditional Chinese Medicine (TCM). The market for CPM in China alone is tens of billions US dollars annually and some of the CPM are also used as dietary supplements for health augmentation in the western countries. But concerns continue to be raised about the legality, safety and efficacy of many popular CPM. Here we report a pioneer work of applying molecular biotechnology to the identification of CPM, particularly well refined oral liquids and injections. What's more, this PCR based method can also be developed to an easy to use and cost-effective visual chip by taking advantage of G-quadruplex based Hybridization Chain Reaction. This study demonstrates that DNA identification of specific Medicinal materials is an efficient and cost-effective way to audit highly processed CPM and will assist in monitoring their quality and legality.

  2. [Establishment of traceability system of Chinese medicinal materials' quality].

    Science.gov (United States)

    Qi, Yao-dong; Gao, Shi-man; Liu, Hai-tao; Li, Xi-wen; Wei, Jian-he; Zhang, Ben-gang; Sun, Xiao-bo; Xiao, Pei-gen

    2015-12-01

    The quality of Chinese medicinal materials relates greatly to the clinical curative effect and security. In order to ensure the quality and safety of Chinese medicinal materials, a systematic and operable traceability system needs to be established. It can realize the whole process of quality and safety management of Chinese medicinal materials "from production to consumption" through recording and inquiring information and recalling defective products, which is an important direction for the future development of traditional Chinese medicine. But it is still at the exploration and trial stage. In this paper, a framework of Chinese medicinal materials' quality and safety traceability system was established on the basis of the domestic and international experience about the construction of food and agricultural products traceability systems. The relationship between traceability system of Chinese medicinal materials' quality and GAP, GMP, GSP was analyzed, and the possible problems and the corresponding solutions were discussed. PMID:27141688

  3. [Application of magnetic materials in analysis on Chinese herb medicines].

    Science.gov (United States)

    Xu, Li-Wei; Wang, Jiu-Rong; Han, Xue-Feng

    2012-12-01

    China is the cradle of Chinese herb medicines,with rich plant resources. However, traditional processing methods have many disadvantages, such as high comsumption of organic solvent, long extraction time and high loss of effective constituents. For the purpose of rational use of Chinese herb medicines and accurate analysis on their constituents,the sample pre-treatment method with magnetic nanoparticles as the carrier brought new opportunities in recent years. after consulting literatures,the essay summarizes traditional extraction methods of Chinese herb medicines, characteristics of magnetic materials and their application in the analysis on Chinese herb medicines. PMID:23477130

  4. DNA based identification of medicinal materials in Chinese patent medicines

    OpenAIRE

    Rong Chen; Juan Dong; Xin Cui; Wei Wang; Afshan Yasmeen; Yun Deng; Xiaomao Zeng; Zhuo Tang

    2012-01-01

    Chinese patent medicines (CPM) are highly processed and easy to use Traditional Chinese Medicine (TCM). The market for CPM in China alone is tens of billions US dollars annually and some of the CPM are also used as dietary supplements for health augmentation in the western countries. But concerns continue to be raised about the legality, safety and efficacy of many popular CPM. Here we report a pioneer work of applying molecular biotechnology to the identification of CPM, particularly well re...

  5. [Research progress of Chinese herbal medicine raw materials in cosmetics].

    Science.gov (United States)

    Xie, Yan-jun; Kong, Wei-jun; Yang, Mei-hua; Yang, Shi-hai

    2015-10-01

    Advocating green, nature, environmental protection, safety and the pursuit of efficacy are the trends of cosmetics in the world. In recent years, more and more Chinese herbal extracts with mild, high safety and small irritation are applied to cosmetics as the natural additives. This has become a new hot spot. The recent application advances of Chinese medicine raw materials in cosmetics are overviewed according to their main functions. This review will provide useful references for the future development and application of Chinese medicinal herbs cosmetics. PMID:27062803

  6. [Research progress of Chinese herbal medicine raw materials in cosmetics].

    Science.gov (United States)

    Xie, Yan-jun; Kong, Wei-jun; Yang, Mei-hua; Yang, Shi-hai

    2015-10-01

    Advocating green, nature, environmental protection, safety and the pursuit of efficacy are the trends of cosmetics in the world. In recent years, more and more Chinese herbal extracts with mild, high safety and small irritation are applied to cosmetics as the natural additives. This has become a new hot spot. The recent application advances of Chinese medicine raw materials in cosmetics are overviewed according to their main functions. This review will provide useful references for the future development and application of Chinese medicinal herbs cosmetics.

  7. [HRM identification of Chinese medicinal materials Mutong].

    Science.gov (United States)

    Hu, Jun; Zhan, Zhi-lai; Yuan, Yuan; Huang, Lu-qi; Liu, Yong

    2015-06-01

    High resolution melting (HRM), an important technology for genotyping and mutation scanning, has broad prospects in the authentification of traditional Chinese medicine. This paper selected universal trnH-psbA primers and used HRM to establish a new methods for identification of Akebia herbs. PCR was conduct at the annealing temperature of 58 degrees C and 35 cycles. The range of the DNA template concentration, the primer concentration and the Mg2+ ion concentration were further analyzed. The results showed the Tm values of Caulis Akebiae was (81.84 ± 0.16), (85.28 ± 0.16) degrees C and Caulis Clematidis Armandii was (83.22 ± 0.19) degrees C and Caulis Aristolochiae manshuriensis was (81.67 ± 0.14) degrees C, (84.24 ± 0.10) degrees C with 5-125 mg - L-' DNA template, 0.4 μmol x L(-1) primer, 2.0 mmol x L(-1) Mg2+. This method can achieve the authentification of Akebia herbs and is simple, fast, high-throughput, visual. PMID:26591514

  8. Reason Analysis and Risk Prevention of Soaring Price of Traditional Chinese Medicinal Materials

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    In recent years,the price of traditional Chinese medicinal materials soars continuously,and the resulting price risk increasingly looms large,which has critically affected midstream and downstream industries and peoples’ demand for drug,and imperiled healthy and orderly development of traditional Chinese medicinal industries.Based on the status quo of continuous skyrocketing price of traditional Chinese medicinal materials at present,we winkle out the root cause of soaring price as follows:the supply and demand lose balance;the production costs hike up;there are other factors responsible for soaring price.This paper further analyses the impact of sharp increase in price of traditional Chinese medicinal materials on all links of industry chain as follows:the medicinal herb growers never benefit from soaring price;the counterfeiters and forgers in midstream industry increase;the gross profit rate of Chinese medicine enterprises declines.In accordance with the risk arising from abnormal fluctuation in price of traditional Chinese medicinal materials,corresponding precautionary measures are put forward as follows:promote the quality of traditional Chinese medicinal materials through management of value chain;curtail the production and management cost of traditional Chinese medicinal materials through management of organization chain;stabilize price of traditional Chinese medicinal materials through management of information chain;reduce transaction cost of traditional Chinese medicinal materials through management of logistics chain.

  9. Reason Analysis and Risk Prevention of Soaring Price of Traditional Chinese Medicinal Materials

    OpenAIRE

    Zhao, Huan; Liu, Jian-qiu; Qu, Kai-yue; Feng, Li; He, Yi

    2011-01-01

    In recent years, the price of traditional Chinese medicinal materials soars continuously, and the resulting price risk increasingly looms large, which has critically affected midstream and downstream industries and peoples' demand for drug, and imperiled healthy and orderly development of traditional Chinese medicinal industries. Based on the status quo of continuous skyrocketing price of traditional Chinese medicinal materials at present, we winkle out the root cause of soaring price as foll...

  10. Harmonization of monographic standards is needed to ensure the quality of Chinese medicinal materials

    Directory of Open Access Journals (Sweden)

    Zhao Sandy

    2009-09-01

    Full Text Available Abstract This article provides an overview on the regulations of Chinese medicinal materials (CMMs in various countries and regions. Harmonization of CMM monographs would provide standards for the quality control of CMM products and play an important role in the modernization and globalization of Chinese medicine. A harmonized regulatory system would improve the quality of CMMs thereby ensuring the safety of the products and assisting Chinese medicine practitioners in their practice. The fast growing demand worldwide for traditional medicines calls for harmonized monographic standards to safeguard the safety and quality of CMM products.

  11. [Several common types of counterfeit and inferior drugs in Chinese medicinal materials market].

    Science.gov (United States)

    Liu, Yimei; Chen, Keli

    2012-04-01

    Though there are many species of counterfeit and inferior drugs of Chinese Medicinal Materials in the market, the means of fabrication is common. According to our investigating and reports in the literature it is found that the counterfeits and inferior drugs exist in 4 styles: counterfeits, reused medicinal materials and their slices which have been extracted by boiling water or ethanol, medicinal materials and their slices which have been added with non-medicinal parts or chemicals, medicinal materials which have no enough growth time or have been reserved for a long time. Through summarizing the styles and their common characteristics of the counterfeits and inferior drugs,it is helpful to raise vigilance and detect them.

  12. TRADITIONAL CHINESE HERBAL MEDICINE

    NARCIS (Netherlands)

    ZHU, YP; WOERDENBAG, HJ

    1995-01-01

    Herbal medicine, acupuncture and moxibustion, and massage and the three major constituent parts of traditional Chinese medicine. Although acupuncture is well known in many Western countries, Chinese herbal medicine, the mos important part of traditional Chinese medicine, is less well known in the We

  13. [Diagnosis and integrative evaluation on soil fertility of three Chinese medicinal materials in GAP plots].

    Science.gov (United States)

    Pan, Chaomei; Huang, Haibo; Zhan, Ruoting; Xu, Honghua; Liao, Guanrong

    2002-03-01

    The fertility of soil was diagnosed and integratively evaluated by modified Nemoro Index with eight indexes, i.e. pH, organic matter, total N, P, K and available N, P, K on three national Chinese medicinal materials GAP (Good Agricultural Practice) experimental plots of Pogostemon cablin, Citrus medica and Morinda officinalis in Guangdong. The results showed that the pH, organic matter and other major nutrient contents were low and imbalance. There are lots of nutritive disturbance factors. The level of soil integrative fertility in any of the plots was poor. PMID:12583155

  14. [Application of support vector machine approach in studying nephron toxicity of Chinese medicinal materials].

    Science.gov (United States)

    Zhang, Jing-fang; Jiang, Lu-di; Zhang, Yan-ling

    2015-03-01

    On the basis of web databases, 111 compounds with nephrotoxicity and 90 compounds without nephrotoxicity were collected as data set of nephrotoxicity discrimination model, 39 compounds with tubular necrosis and 39 compounds without tubular necrosis were collected as data set of tubular necrosis discrimination model. The 6 122 molecular descriptors, including physicochemical, charge distribution and geometrical descriptors were calculated to characterize the molecular structure of the above-mentioned compounds. CfsSubsetEval valuation method and BestFirst-D1-N5 searching method were used to select molecular descriptors. Two models with high accuracy were built based on the support vector machine (SVM) approach, respectively. Accuracy, sensitivity, specificity and matthew's correlation coefficient of the two models were all above 70%. By using 22 nephrotoxicity compounds of Chinese medicine, the nephrotoxicity discrimination model was further verified with an accuracy of 72.73%. Using the tubular necrosis discrimination model, 10 potential compounds which can cause tubular necrosis were screened from the positive results of nephrotoxicity discrimination model, 6 of them have been verified by literatures. The results demonstrated that the discrimination models can be applied to screen nephrotoxic compounds from Chinese medicinal materials, and they also offer a new research idea for the further studies on the mechanism of nephrotoxicity. PMID:26226759

  15. History of Chinese medicinal wine.

    Science.gov (United States)

    Xia, Xun-Li

    2013-07-01

    Chinese medicinal wine is one type of a favorable food-drug product invented by Chinese ancestors for treating and preventing diseases, promoting people's health and corporeity, and enriching people's restorative culture. In the course of development of the millenary-old Chinese civilization, Chinese medicinal wine has made incessant progress and evolution. In different historical periods, Chinese medicinal wine presented different characteristics in basic wine medical applications, prescriptions, etc. There are many medical and Materia Medica monographs which have systemically and specifically reported on Chinese medicinal wine in past Chinese dynasties. By studying leading medical documents, this article made an outline review on the invention, development, and characteristics of Chinese medicinal wine.

  16. Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    2009013 Clinical observation on treatment of active rheumatoid arthritis with Chinese herbal medicine. SHENG Zhenghe(盛正和), et al.Dept TCM, 5th Affili Hosp, Guangxi Med Univ, Guangxi 545001. Chin J Integr Tradit West Med 2008;28(11):990-993. Objective To study the efficacy and safety of Chinese drugs for expelling evil-wind, removing dampness, promoting blood circulation and invigorating yin in treating active rheumatoid arthritis (RA).

  17. Transmitting Chinese Medicine

    Science.gov (United States)

    Scheid, Volker

    2015-01-01

    Historians of Chinese medicine acknowledge the plurality of Chinese medicine along both synchronic and diachronic dimensions. Yet, there remains a tendency to think of tradition as being defined by some unchanging features. The Chinese medical body is a case in point. This is assumed to have been formalised by the late Han dynasty around a system of internal organs, conduits, collaterals, and associated body structures. Although criticism was voiced from time to time, this body and the micro/macrocosmic cosmological resonances that underpin it are seen to persist until the present day. I challenge this view by attending to attempts by physicians in China and Japan in the period from the mid 16th to the late 18th century to reimagine this body. Working within the domain of cold damage therapeutics and combining philological scholarship, empirical observations, and new hermeneutic strategies these physicians worked their way towards a new territorial understanding of the body and of medicine as warfare that required an intimate familiarity with the body’s topography. In late imperial China this new view of the body and medicine was gradually re-absorbed into the mainstream. In Japan, however, it led to a break with this orthodoxy that in the Republican era became influential in China once more. I argue that attending further to the innovations of this period from a transnational perspective - commonly portrayed as one of decline - may help to go beyond the modern insistence to frame East Asian medicines as traditional. PMID:26869864

  18. History of Chinese medicinal wine.

    Science.gov (United States)

    Xia, Xun-Li

    2013-07-01

    Chinese medicinal wine is one type of a favorable food-drug product invented by Chinese ancestors for treating and preventing diseases, promoting people's health and corporeity, and enriching people's restorative culture. In the course of development of the millenary-old Chinese civilization, Chinese medicinal wine has made incessant progress and evolution. In different historical periods, Chinese medicinal wine presented different characteristics in basic wine medical applications, prescriptions, etc. There are many medical and Materia Medica monographs which have systemically and specifically reported on Chinese medicinal wine in past Chinese dynasties. By studying leading medical documents, this article made an outline review on the invention, development, and characteristics of Chinese medicinal wine. PMID:21853349

  19. TRADITIONAL CHINESE MEDICINE

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    930433 A study on relationship between hy-pothyroidism and deficiency of kidney YANG.ZHA Lianglun(查良伦),et al.lnstit Integr TCM& West Med,Shanghai Med Univ,Shanghai,200040.Chin J Integr Tradit & West Med 1993;13(4):202—204.Thirty—two cases of hypothyroidism causedby various factors were treated for one year withChinese medicinal herbs preparation“Shen Lutablet”(SLT)to warm and reinforce the KidneyYang.34 normal persons were studied as a con-trol group.After treatment with SLT,the clini-cal symptoms of hypothyroidism were markedlyimproved.Average serum concentration of totalT3,T4 increased significantly from 67.06±4.81

  20. Use of the Metabolomics Approach to Characterize Chinese Medicinal Material Huangqi

    Institute of Scientific and Technical Information of China (English)

    Li-Xin Duan; Xiaoquan Qi; Tian-Lu Chen; Ming Li; Min Chen; Ye-Qing Zhou; Guang-Hong Cui; Ai-Hua Zhao; Wei Jia; Lu-Qi Huang

    2012-01-01

    Integration of the genetic and metabolic fingerprinting can provide a new approach to differentiate similar Traditional Chinese Medical (TCM) materials.Two leguminous plants,Mojia Huangqi and Menggu Huangqi,are important medical herbs and share great similarities in morphology,chemical constituent,and genomic DNA sequence.The taxonomy of Mojia Huangqi and Menggu Huangqi has been debated for more than 50 years and discrimination of TCM materials directly affects the pharmacological and clinical effects.AFLP based genetic fingerprinting and GC-TOF/MS-based metabolic fingerprinting were used to successfully discriminate the two species.The results of AFLP supported the opinion that Menggu Huangqi was a variant of Mojia Huangqi.The metabolic fingerprinting showed growth locations have greater impacts on the metabolite composition and quantity than the genotypes (cultivated versus wild) in Menggu Huangqi.The difference of some soluble sugars,fatty acids,proline,and polyamine reflected plant adaptation to different growth environments.Using multivariate and univariate statistical analysis,three AFLP markers and eight metabolites were identified as candidate DNA and metabolic markers to distinguish the two herb materials.The correlation network between AFLP markers and metabolites revealed a complex correlation network,which indicated the special metabolic pathways and the regulation networks of Huangqi.

  1. A Novel Sample Introduction Technique for the Simultaneous Determination of As, Se, Ge and Hg in Chinese Medicinal Material

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A novel technique of Moveable Reduction Bed Hydride Generator(MRBHG) was applied to the hydride generation or cold vapor generation of As, Se, Ge, and Hg existing in Traditional Chinese Medicinal Material(TCM). The simultaneous determination of the multi-elements was performed with ICP-MS. A solid reduction system involving the use of potassium tetraborohydride and tartaric acid was applied to generating metal hydride or cold vapor efficiently. The factors affecting the metal cold vapor generation were studied. The main advantage of the technique is that only a 4 μL volume of sample was required for the cold vapor generation. The absolute detection limits of all the elements studied are in 10-12 g level.

  2. Published papers about Salvia miltiorrhiza Bunge as a Chinese medicinal material

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Xu Cuihong, Shu Zhiming, Wang Yan, Miao Fang, Zhou ke. The accumulation rule of the main medicinal components in different organs of Salvia miltiorrhiza Bunge. and Salvia miltiorrhiza Bunge. f. alba. Lishizhen Medicine and Materia Medica Research, 2010, 21(09): 2129-2132. Email: miaofangmf@ 163,com

  3. Comparison of Sasang Constitutional Medicine, Traditional Chinese Medicine and Ayurveda

    Directory of Open Access Journals (Sweden)

    Jong Yeol Kim

    2011-01-01

    Full Text Available Sasang constitutional medicine (SCM, traditional Chinese medicine (TCM and Ayurveda are three different forms of Asian traditional medicine. Although these traditions share a lot in common as holistic medicines, the different philosophical foundations found in each confer distinguishing attributes and unique qualities. SCM is based on a constitution-based approach, and is in this way relatively more similar to the Ayurvedic tradition than to the TCM, although many of the basic SCM theories were originally derived from TCM, a syndrome-based medicine. SCM and TCM use the same botanical materials that are distributed mainly in the East Asian region, but the basic principles of usage and the underlying rationale are completely different from each other. Meanwhile, the principles of the Ayurvedic use of botanical resources are very similar to those seen in SCM, but the medicinal herbs used in Ayurveda generally originate from the West Asian region which displays a different spectrum of flora.

  4. [Research on resources chemistry of Chinese medicinal materials and resources recycling utilization ways and goals and tasks].

    Science.gov (United States)

    Duan, Jin-ao; Su, Shu-lan; Guo, Sheng; Jiang, Shu; Liu, Pei; Yan, Hui; Qian, Da-wei; Zhu, Hua-xu; Tang, Yu-ping; Wu, Qi-nan

    2015-09-01

    The objects of research on the resources chemistry of Chinese medicinal materials (RCCMM) are promotion of efficient production, rational utilization and improving quality of CMM and natural products. The development of TCM cause depends on the efficient utilization and sustainable development of CMM, hinges on the technologies and methods for using and discovering medicinal biological resources, stand or fall on the extension of industy chains, detailed utilizaion of resource chemical components by multi-way, multi-level. All of these may help to the recycling utilization and sound development of RCMM. In this article, five respects were discussed to the RCCMM researches and resources recycling utilization ways and goals and tasks. First, based on the principle of resource scarcity, discovering or replacing CMM resources, protecting the rare or endangered species or resources. Second, based on the multifunctionality of CMM, realizing the value-added and value compensation, and promoting the utilization efficiency through systermatic and detailed exploitation and utilization. Third, based on the resource conservation and environment-friendly, reducing raw material consumption, lowering cost, promoting recycling utilization and elevating utilization efficiency. Fourth, based on the stratege of turning harm into good, using the invasive alien biological resources by multi-ways and enriching the medicial resources. Fifth, based on the method of structure modification of chemical components, exploring and enhancing the utility value of resouces chemical substances. These data should provide references and attention for improving the utilization efficiency, promoting the development of recycling economy, and changing the mode of economic growth of agriculture and industry of CMM fundamentally. PMID:26978979

  5. Traditional Chinese medicine for primary liver cancer

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    @@ Further progress has been made in the traditional Chinese medicine for primary liver cancer over the past few years, especially in the research of traditional Chinese medicine (TCM) treatment principle, improvement of therapeutic results and prolonging the survival.

  6. 电子舌对中药滋味的区分辨识%Discrimination of traditional Chinese medicinal materials with different tastes based on electronic tongue

    Institute of Scientific and Technical Information of China (English)

    杜瑞超; 王优杰; 吴飞; 冯怡; 徐德生; 洪燕龙; 阮克锋

    2013-01-01

    Objective:To investigate the use of the electronic tongue in the evaluation of traditional Chinese medicinal materials with sour,bitter,sweet or salty tastes,and assess the possible application of the sensor in the evaluation of different tastes of traditional Chinese medicinal materials.Method:Aqueous extracts of 22 traditional Chinese medicinal materials were measured by the electronic tongue.The data collected with the tongue was evaluated for discrimination of the samples with multivariate statistical methods:principal component analysis (PCA) and discriminant factor analysis (DFA).Result:The electronic tongue was capable of discriminating between samples with different taste modalities and could also distinguish different samples eliciting the same basic taste.Twenty-two traditional Chinese medicinal materials could be classified into five clusters based on PCA.These differences seem to derive from the different tastes.DFA was applied to construct a model to discriminate traditional Chinese medicinal materials with different tastes.And the samples yielded about 88.2% accuracy for cross-validation.Conclusion:We confirmed that the electronic tongue may provide an analytical procedure for classification of the samples with respect to tastes of the traditional Chinese medicinal materials.%目的:利用电子舌对中药的滋味进行区分辨识.方法:对22种常用中药的水煎液进行电子舌检测,采用主成分分析、判别因子分析等统计分析方法对检测数据进行分析.结果:通过主成分分析可以区分不同滋味的药材以及相同滋味的不同药材;在主成分分析图上,22种中药按酸、苦、甜、咸的规律聚类分布;得到的酸、苦、甜、咸特征雷达图形状不同,可以很好的区分中药不同滋味;用判别因子分析建立滋味判别模型,并进行交叉验证,正确率为88.2%.结论:电子舌能够对中药滋味进行精确地区分辨识,结合统计方法,可以建立中药滋味判别模型.

  7. Application of magnetic materials in analysis on Chinese herb medicines%纳米磁性材料在中草药分析中的应用

    Institute of Scientific and Technical Information of China (English)

    许丽卫; 王久荣; 韩雪峰

    2012-01-01

    China is the cradle of Chinese herb medicines,with rich plant resources. However,traditional processing methods have many disadvantages, such as high comsumption of organic solvent, long extraction time and high loss of effective constituents. For the purpose of rational use of Chinese herb medicines and accurate analysis on their constituents,the sample pre-treatment method with magnetic nanoparticles as the carrier brought new opportunities in recent years, after consulting literatures, the essay summarizes traditional extraction methods of Chinese herb medicines, characteristics of magnetic materials and their application in the analysis on Chinese herb medicines.%近些年来,以磁性纳米粒子作为载体的样品前处理方法给中草药分析带来了新的契机.该文通过文献查阅,对中草药提取分离方法、纳米磁性材料的特点及其在中草药分析中的应用进行了综述.

  8. Clinical Service of Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ The clinical practice of traditional Chinese medicine (TCM) faces three major challenges:(1)How to enhance its contribution on overall medical service quality? (2) How to best address the unmet medical needs in the contemporary society? (3)How to guarantee that the traditional perspective for disease diagnosis and treatment not be neglected in clinical practice?

  9. 药材红花、蒲黄的染色鉴定%Identification of the chemical dyes in Chinese medicinal materials flos carthami and pollen typhae

    Institute of Scientific and Technical Information of China (English)

    龚海燕

    2014-01-01

    To identify the chemical dyes in Chinese medicinal materials flos carthami and polen typhae.Methods:TLC and HPLC-DAD.Results:Orange II was discovered in flos carthami and auramine O in polen typhae.Conclusions:the situation of the adulteration in Chinese medicinal materials flos carthami and polen typhae was very severe.%目的:对红花和蒲黄中化工染料进行染色鉴定。方法:TLC法和HPLC-DAD法鉴定。结果:红花中检出金橙II;蒲黄中检出金胺O;结论:红花、蒲黄掺假染色现象非常严重。

  10. Instruction to Authors of Chinese Herbal Medicines

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ Chinese Herbal Medicines, an international journal sponsored by the Tianjin Institute of Pharmaceutical Research and Institute of Medicinal Plant Develop-ment. The Journal s purpose is to provide a forum for the studies on Chinese herbal medicines, traditional medicines, and natural products.

  11. Determination of production regions for pollution-free Chinese medicinal materials by geographic information system: Achyranthes bidentata (Niu Qi) in Tianjin as an example

    OpenAIRE

    Xie, Cai-xiang; Wang, Huan; Huang, Lin-Fang; Li, Hui; Song, Jing-Yuan

    2014-01-01

    Background The land and ecology suitability for producing pollution-free Chinese medicinal materials should be evaluated based on Geographic Information System (GIS). This study aims to determine production regions for pollution-free Achyranthes bidentata in Tianjin as a case to illustrate the workflow based on GIS. Methods The slopes, land usage, residential areas and roads were selected to evaluate the land suitability, to avoid the potential pollution sources. The ecology suitability evalu...

  12. Current Situation and Prospects of Bionic Cultivation of Chinese Medicinal Materials%中药材仿生栽培效益分析及其展望

    Institute of Scientific and Technical Information of China (English)

    倪鼎文

    2016-01-01

    中药材仿生栽培是根据药用植物生长发育习性及其对生态环境的要求,吸取传统农业的精华,采用现代农业生产技术,运用系统工程方法再现药用植物与外界环境的生态关系而进行中药材集约化生产的模式,具有明显的经济效益、生态效益和社会效益,实行道地中药材的仿生栽培,对保护生态环境、提高栽培药材质量、满足社会用药需求均具有重要意义,也是保证中药资源可持续发展最有效的途径。%Bionic cultivation of Chinese medicinal materials is an intensive Chinese herbal medicine production mode, applying engineering approach in reappearing ecological relationship between medical plants and external environment, adopting modern agricultural production technique, and absorbing the essence of traditional agriculture according to the growth habits of medicinal plants and their requirements on ecological environment. It has obvious economic benefits, ecological benefits and social benefits, adopts the bionic cultivation of authentic Chinese herbal medicine, which has great significance to protecting the ecological environment, improving the quality of cultivation of medicinal materials, meeting the demand of social medicine, and is also the most effective way to ensure the sustainable development of TCM resources.

  13. Microscopic identification of Chinese medicinal materials based on X-ray phase contrast imaging: from qualitative to quantitative

    Science.gov (United States)

    Xue, Y.; Liang, Z.; Tan, H.; Ni, L.; Zhao, Z.; Xiao, T.; Xu, H.

    2016-07-01

    Although a variety of methods, ranging from simple morphological examination to physical and chemical analysis, and DNA molecular biology, exist for authenticating Chinese medicinal materials(CMMs), no methods can achieve both the source species identification and quality evaluation of CMMs simultaneously. Furthermore, the methods that are currently available for the identification of CMMs, including both optical and electronic microscopy, usually entail strict requirements for sample preparation or testing environment, such as the slicing of super-thin sections, or processing with specific chemical reagents. These treatments not only damage the CMMs but may also cause some of the original microstructures to be missed. Additionally, they may even yield false results. Owing to the unique penetrating character of X-rays, X-ray phase contrast imaging(XPCI) can be used to realize the inner microstructures of CMMs through nondestructive imaging. With the higher flux and luminance of the third generation of synchrotron radiation facility, XPCI can provides clearer and finer microstructures of CMMs, which are mainly composed of C, H, O, and N elements, with better spatial and density resolutions. For more than ten years, the X-ray imaging group at the Shanghai Institute of Applied Physics has investigated the microstructures of CMMs by XPCI and they have established and developed a quantitative X-ray phase contrast micro-CT for investigating the characteristic microstructures of CMMs. During this period, a variety of typical CMMs have been investigated, from two-dimensional (2D) radiography to three-dimensional (3D) micro-CT, from qualitative to quantitative. Taken together, these results verify that quantitative X-ray phase contrast micro-CT is a practical tool for the microscopic investigation of CMMs. Additionally, further efforts are being made to find the relationship between the microstructures' quantitative factors and active chemical components. At present

  14. Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    2007134 Clinical study on "Jin′s three-needling" in the treatment of generalized anxiety disorder. LUO Wenzheng(罗文政), et al. Coll Acupunct & Massage, Guangzhou TCM Univ, Guangzhou 510405. Chin J Integr Trad & West Med 2007;27(3):201-203. Objective To study the clinical effect of "Jin′s three-needling" in the treatment of generalized anxiety disorder. Methods Fifty-eight patients with generalized anxiety were randomly assigned to two groups equally. the medication group treated with anti-anxiety drugs and the acupuncture group with "Jin′s three-needling". The treatment course was 6 weeks. The clinical effects were evaluated with Hamilton anxiety scale (HAMA), clinical global impression (CGI), and treatment emergent symptom scale (TESS) before treatment and at the end of 2nd, 4th, 6th week of the treatment course. The concentration of 5-hydroxytryptamine (5-HT) in platelet, and plasma levels of corticosterone (CS) and adrenocorticotropic hormone (ACTH) were measured with high performance liquid chromatography-electrochemical detection (HPLC-ED) method before and after treatment. Results The clinical effects in the two groups were equivalent, while the adverse reaction found in the acupuncture group was less than that in the medication group (P<0.05). The platelet concentration of 5-HT and plasma ACTH level decreased significantly in both groups after treatment with insignificant difference between the group (P<0.05). The plasma CS level had no obvious change in the two groups after treatment as compared with that before treatment.Conclusion "Jin′s three-needling" shows similar curative effect on generalized anxiety to routine Western medicine but with less adverse reaction, which may be realized through regulating the platelet 5-HT concentration and plasma ACTH level.

  15. Chinese integrative medicine:inclusion of a Chinese medicine programme in a conventional medical institute

    Institute of Scientific and Technical Information of China (English)

    Hai-Yong Chen; Yibin Feng; Lixing Lao

    2014-01-01

    To meet community demands with optimal Chinese and conventional medical treatment, the University of Hong Kong is promoting integrative medicine by developing Chinese medicine programmes that train students of both Western and Chinese medicine. The programmes emphasize multi-disciplinary training and interaction between the two therapeutic approaches, enabling students to establish reliable, consistent, and respectful mutual cooperation in their future careers.

  16. Chinese traditional medicine for induction of ovulation

    Institute of Scientific and Technical Information of China (English)

    肖碧莲

    2003-01-01

    This is a review paper of some effective recipes of Chinese traditional medicine usedin ovulation induction and treatment of gynecological diseases. Some clinical results bygynecologists using Chinese traditional medicine in combination with western medicineand results from research on traditional medicine with modern technology are presented.A list of frequently used traditional medicine for ovulation induction are selected from the famous Compendium of Materica Medica(本草纲目)by Li Shi-zhen(李时珍).

  17. Distribution and Elimination of Lead Species in Soils Related to GAP of Chinese Medicinal Materials of Ligusticum Chuanxiong Hort

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    In this paper, the sequential extraction procedure was used for the selection of fractions of lead in seven stages corresponding to lead exchangeable, lead bounded to carbonates, to manganese oxides, to organic matters, to amorphous iron, and lead associated to crystallized iron, and to residuals. The vertical distributions of lead species were carried out in the soils related to good agriculture progress (GAP) of Chinese medical materials of Ligusticum chuanxiong Hort in Dujiangyan city and Wenchuan Co...

  18. Chinese medicinal herbs for chronic hepatitis B

    DEFF Research Database (Denmark)

    Liu, J; McIntosh, H; Lin, Haili

    2001-01-01

    Chronic hepatitis B is a serious health problem worldwide. Chinese medicinal herbs are widely used for treatment of chronic hepatitis B in China and many clinical trials have been conducted. This systematic review is to assess the efficacy and safety of Chinese medicinal herbs for chronic hepatitis...

  19. Approaches in Treating AIDS with Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    吕维柏

    2002-01-01

    @@ Editorial: AIDS is the archenemy of mankind, it also threatened Chinese people seriously. Although anti-retroviral drugs are effective, yet too expensive, the majority of 600 000 Chinese patients can't afford to purchase and use them. Decades ago, some scientists were trying to use Chinese Medicine in treating AIDS, experienc e gained but problems also exposed concerning strategy of research, methodol ogy, racial difference, Chinese drugs screening, integrative Chinese and western medicine, HIV and immunity, etc., sustained and integrative effort would bring safe, effective, and affordable drugs for the fatal pandemic all over the world

  20. Traditional Chinese Medicine in the Prevention of Disease

    Directory of Open Access Journals (Sweden)

    Claudia Patricia Ardila Jaimes

    2015-05-01

    Full Text Available Introduction: Traditional Chinese medicine is based on the oriental philosophy developed thousands of years ago, their understanding involves a deep understanding and knowledge of it. Materials and methods: This article seeks to reflect on the philosophy behind Chinese medicine and the role it has played in preventing the disease. Results: Three perspectives related to the philosophical foundations of traditional Chinese medicine and prevention analysis, the rise and popularity of its use in the prevention and the role of science in strengthening the evidence in the therapeutic of Traditional Chinese Medicine addresses. Conclusion: The contribution of TCM to the prevention of diseases can be magnified to the extent that their study will expand and further substantiate its effectiveness.

  1. Role of Traditional Chinese Medicine in Integrative Medicine

    Institute of Scientific and Technical Information of China (English)

    吕爱平; 吕维柏; 吕青平

    2004-01-01

    @@ Complementary & alternative medicine (CAM) is getting more and more important in improving human health. Traditional Chinese medicine (TCM), with her thousands of years history and contributions to the health of Chinese people, definitely is vital in CAM in China. Medical sciences including CAM and mainstream medicine, with unified specific aim, could be integrated and become integrative medicine. During the integration, TCM would contribute much more in the progress with her cultural background and clinical efficacy. This paper will discuss how TCM takes part in the inte gration via her function in clinical practice.

  2. Artemisinin, a miracle of traditional Chinese medicine.

    Science.gov (United States)

    Kong, Ling Yi; Tan, Ren Xiang

    2015-12-19

    The 2015 Nobel Prize in Physiology or Medicine, shared by Professor Youyou Tu, focused worldwide attention on artemisinin, a natural product antimalarial drug inspired by traditional Chinese medicine (TCM). This is the first Nobel Prize in natural sciences presented to a Chinese scientist for her impactful research work in China in collaboration with other Chinese scientists. We are delighted to provide the background and implications of the discovery of artemisinin, along with our personal viewpoints toward the affordability of modern medicines from natural products. PMID:26561737

  3. 我国中成药处方中重点保护野生药材的应用状况分析%Analysis on application of key-protected wild medicinal materials in prescription of Chinese patent medicine

    Institute of Scientific and Technical Information of China (English)

    周跃华; 路金才

    2013-01-01

    以《国家重点保护野生药材物种名录》、《国家重点保护野生动物名录》、《国家重点保护野生植物名录(第一批)》、华盛顿公约(CITES)附录1和附录2等名录中收载且具有法定药材标准的动植物物种所对应的药材品种作为国家重点保护野生药材,对其在我国中成药质量标准“处方”项下出现的频次进行了查询,并结合相关药材人工栽培及养殖的文献,对相关重点保护野生药材在中成药中的应用状况进行初步分析,为其可持续利用提供参考.%As state key-protected wild medicinal materials, their species are collected in State Key-protected Wild Medicinal Species List, State Key-protected Wild Animals List, and State Key-protected Wild Plants List {the first) and Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) Appendix Ⅰ/Ⅱ, and there are legal medicinal material standards. Based on the statistical results of the existence frequency in Chinese patent medicine and the literatures of medicinal materials cultivation and breeding situation, the application of key-protected wild medicinal materials is preliminarily estimated, which would provide the reference for their sustainable utilization.

  4. Shanghai University of Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The 2006 reception conference of the International Education College of the Shanghai University of Traditional Chinese Medicine was held April 28 in Beijing, unveiling its overseas students recruitment program this year.

  5. Chinese Medicine: A Cognitive and Epistemological Review

    OpenAIRE

    Ben Kavoussi

    2007-01-01

    In spite of the common belief that Chinese natural philosophy and medicine have a unique frame of reference completely foreign to the West, this article argues that they in fact have significant cognitive and epistemic similarities with certain esoteric health beliefs of pre-Christian Europe. From the standpoint of Cognitive Science, Chinese Medicine appears as a proto-scientific system of health observances and practices based on a symptomological classification of disease using two elementa...

  6. Chinese medicinal herbs for chronic hepatitis B

    DEFF Research Database (Denmark)

    Liu, J P; McIntosh, H; Lin, Haili

    2001-01-01

    Hepatitis B virus infection is a serious health problem worldwide. Traditional Chinese medicinal herbs have been widely used to treat chronic liver diseases, and many controlled trials have been done to investigate their efficacy.......Hepatitis B virus infection is a serious health problem worldwide. Traditional Chinese medicinal herbs have been widely used to treat chronic liver diseases, and many controlled trials have been done to investigate their efficacy....

  7. The taste sensory evaluation of medicinal plants and Chinese medicines.

    Science.gov (United States)

    Kataoka, Masumi; Tokuyama, Emi; Miyanaga, Yohko; Uchida, Takahiro

    2008-03-01

    The purpose of this study was to investigate the use of the artificial taste sensor in the evaluation of 11 medicinal plants and 10 Chinese medicines with bitter and/or astringent tastes, and to assess the possible application of the sensor in the evaluation of taste and quality control of medicinal products. Aqueous extracts of the six bitter medicinal plants could be classified into three types, and those of the five astringent medicinal plants into two types, on the basis of sensor output pattern profiles. These differences seem to derive from the different structures of the main components. In the principal component analysis of the taste sensor output of 10 Chinese medicines, a new measure developed, the 'Euclidean distance', defined as the distance between a control and the targeted substance on the principal component map. This measure offers a possibility for indicating the different tastes of Chinese medicines. Lastly, we confirmed that berberine adsorption on the surface of the artificial membrane of the taste sensor was of the Langmuir type. The berberine content in extracts of medicinal plants could be evaluated by the taste sensor, and it was shown to be possible to use the taste sensor for the quality control of medicinal plants.

  8. The Origin of Traditional Chinese Medicine and Thinking on Chinese Medicine Development

    Institute of Scientific and Technical Information of China (English)

    Wang Wenkui; Wang Feng; Wang Ling

    2006-01-01

    Although the traditional Chinese medicine (TCM) has developed a profound theory system and a fame of outstanding advantage in curative effect, it seems that the TCM is not quite adaptable to the deveiopment and requirement of the modern society. A principle of "Adopting the advanced part of Western medicine to serve the TCM" should be adhered to for the traditional Chinese medicine. First, TCM should strive for a consensus of TCM theory which focuses on the guiding principles of "diagnosis and treatment based on an overall analysis of the illness and the patient's condition" and "the opposite principle of five internal organs". Among these principles, "keeping relative balance of three internal systems"is a valuable guidance of the diagnosis and treatment theory. Secondly, macroscopic should be integrated with microscopic, totality with parts, phenomenology with materialism. A dialectical law should be applied to guide analysis. In treatment,adjustment and balance are basic principles. It is necessary not only prepare the medicine in advance accoding to the predicted disease of the year, but also adopt methods to restrict disease in advance. Basides, TCM dose type should be ameliorated in order to meet the needs of society.

  9. Study on metagenomics and genuine traditional Chinese medicinal materials%宏基因组学与道地药材研究

    Institute of Scientific and Technical Information of China (English)

    陈晓辰; 宋经元; 董林林; 姚辉; 陈士林; 韩建萍

    2012-01-01

    Metagenomics is a newly developing discipline which applies molecular biological techniques to analyze genomes of the total microbiota. Metagenomics is widely used in various fields, such as medicine, agriculture, marine ecological environment, soil ecological environment. Resorting to its excellent quality and good efficacy, genuine traditional Chinese medicinal materials (TCMM) have been in good graces of many physicians. The geoherbalism formation of TCMM is based on many factors among which the microenvironment of rhizosphere soil plays a important role in formation of secondary metabolism in medicinal plants. This article emphasizes on illustrating the conception, technique, and strategy of metagenomics and its potential application in genuine TCMM and provides new insights in removing the continuous cropping obstacles in medicinal plants.%宏基因组学是将分子生物学技术应用于微生物基因总和研究的一门新兴学科,现已广泛应用于医药、农业、海洋生态环境、土壤生态环境等领域.道地药材凭借其质优、疗效好的优势自古以来被各医家所青睐,其形成与诸多因素有关,其中根际微环境在药用植物次生代谢产物形成中起着重要作用.着重介绍宏基因组学的概念、技术策略以及其在道地药材研究中的应用现状,进一步阐明土壤微生物对道地药材形成机制的影响,并为解决药用植物连作障碍提出新的研究思路.

  10. [Policy recommendations based on SWOT analysis for agricultural industrialization of traditional Chinese medicinal materials--a case study of uncariae ramulus cum uncis from Jianhe county in Guizhou province].

    Science.gov (United States)

    Hu, Yong; Huo, Ke-Yi; Xiang, Hua

    2013-09-01

    This thesis reviews the historical background of agricultural industrialization, and analyzes the major theories of agricultural industrialization. It also utilizes SWOT analysis method to discuss the industrialization of traditional Chinese medicinal materials in Jianhe county, and finally it puts forward the recommendations for its further development. PMID:24380319

  11. [Policy recommendations based on SWOT analysis for agricultural industrialization of traditional Chinese medicinal materials--a case study of uncariae ramulus cum uncis from Jianhe county in Guizhou province].

    Science.gov (United States)

    Hu, Yong; Huo, Ke-Yi; Xiang, Hua

    2013-09-01

    This thesis reviews the historical background of agricultural industrialization, and analyzes the major theories of agricultural industrialization. It also utilizes SWOT analysis method to discuss the industrialization of traditional Chinese medicinal materials in Jianhe county, and finally it puts forward the recommendations for its further development.

  12. Design and Analysis of Harvesting Machine for Rhizomatic Chinese Medicinal Materials%根茎类中药材采收机的设计及分析

    Institute of Scientific and Technical Information of China (English)

    吴芳霞; 倪淑君; 盛时永; 陈小平

    2015-01-01

    At present, the traditional Chinese medicinal materials is largely planted, yet the degree of mining mechanization is very low, and it is high labor-intensitive and inefficient, aiming at these problems, a new harvesting machine for herbs is de-signed in this paper. The herbs harvesting machine is composed of five parts, such as tractor, peeling separation device, lon-gitudinal plough device, supporting bracket and vibration separating device. Medicinal roots and stems of trees are separated by the peeling separation device, tree stems are prodded to both sides automatically by using the longitudinal plowing device, and then dirt and impurities on the roots are removed automatically by using the vibration separating device. Thus it provides an efficient way of mechanized excavation of medicinal materials.%鉴于目前中药材人工种植面积大,但采收机械化程度低、人工操作强度大及效率低下等实际问题,设计一种新型机械化药材挖掘机。整体结构由手扶拖拉机、旋切分离装置、纵向犁地装置、支撑固定架和振动分离装置五大部分组成。通过旋切分离装置实现药材的根茎与树茎旋切分离的功能,采用纵向犁地装置将树茎自动拨至采挖地两旁,再以振动分离装置自动去除根茎上的泥土与杂质,提供了一种高效率的机械化采收药材的途径。

  13. Spectral Analysis of Chinese Medicinal Herbs Based on Delayed Luminescence

    Directory of Open Access Journals (Sweden)

    Jingxiang Pang

    2016-01-01

    Full Text Available Traditional Chinese medicine (TCM plays a critical role in healthcare; however, it lacks scientific evidence to support the multidimensional therapeutic effects. These effects are based on experience, and, to date, there is no advanced tool to evaluate these experience based effects. In the current study, Chinese herbal materials classified with different cold and heat therapeutic properties, based on Chinese medicine principles, were investigated using spectral distribution, as well as the decay probability distribution based on delayed luminescence (DL. A detection system based on ultraweak biophoton emission was developed to determine the DL decay kinetics of the cold and heat properties of Chinese herbal materials. We constructed a mathematical model to fit the experimental data and characterize the properties of Chinese medicinal herbs with different parameters. The results demonstrated that this method has good reproducibility. Moreover, there is a significant difference (p<0.05 in the spectral distribution and the decay probability distribution of Chinese herbal materials with cold and heat properties. This approach takes advantage of the comprehensive nature of DL compared with more reductionist approaches and is more consistent with TCM principles, in which the core comprises holistic views.

  14. Structural characterization and discrimination of Chinese medicinal materials with multiple botanical origins based on metabolite profiling and chemometrics analysis: Clematidis Radix et Rhizoma as a case study.

    Science.gov (United States)

    Guo, Lin-Xiu; Li, Rui; Liu, Ke; Yang, Jie; Li, Hui-Jun; Li, Song-Lin; Liu, Jian-Qun; Liu, Li-Fang; Xin, Gui-Zhong

    2015-12-18

    Traditional Chinese medicines (TCMs)-based products are becoming more and more popular over the world. To ensure the safety and efficacy, authentication of Chinese medicinal materials has been an important issue, especially for that with multiple botanical origins (one-to-multiple). Taking Clematidis Radix et Rhizoma (CRR) as a case study, we herein developed an integrated platform based on metabolite profiling and chemometrics analysis to characterize, classify, and predict the "one-to-multiple" herbs. Firstly, the predominant constituents, triterpenoid saponins, in three Clematis CRR were rapid characterized by a novel UPLC-QTOF/MS-based strategy, and a total of 49 triterpenoid saponins were identified. Secondly, metabolite profiling was performed by UPLC-QTOF/MS, and 4623 variables were extracted and aligned as dataset. Thirdly, by using pattern recognition analysis, a clear separation of the three Clematis CRR was achieved as well as a total number of 28 variables were screened as the valuable variables for discrimination. By matching with identified saponins, these 28 variables were corresponding to 10 saponins which were identified as marker compounds. Fourthly, based on the relative intensity of the marker compounds-related variables, genetic algorithm optimized support vector machines (GA-SVM) was employed to predict the species of CRR samples. The obtained model showed excellent prediction performance with a prediction accuracy of 100%. Finally, a heatmap visualization was employed for clarifying the distribution of identified saponins, which could be useful for phytochemotaxonomy study of Clematis herbs. These results indicated that our proposed platform was a powerful tool for chemical profiling and discrimination of herbs with multiple botanical origins, providing promising perspectives in tracking the formulation processes of TCMs products. PMID:26610614

  15. Promoting the Development of Traditional Chinese Medicine in the New Century

    Institute of Scientific and Technical Information of China (English)

    佘静

    2001-01-01

    @@Reviewing the past, traditional Chinese medicine (TCM) in the 20th century experienced vicissitude. Since the founding the People's Republic of China, especially for the past twenty years, traditional Chinese medicine undertaking, full of vigor and vitality, has made an unprecedented development in China. The legal status and scientific status of traditional Chinese medicine and pharmacology have already been established. The medical system of traditional Chinese medicine, which is composed of traditional Chinese medicine hospitals, ethnic minority medicine hospitals, integration of traditional and western medicine hospitals and comprehensive hospitals, is playing an important role in preventing, treating diseases and enhancing people's health level. The system of production and circulation for traditional Chinese medicine has basically guaranteed the people's demand for Chinese medicine, with the principles of producing medicinal materials as basis, taking Chinese medicine industry as pillar and Chinese medicine as link. Remarkable achievements have been scored in the research of TCM development as well as research of TCM basic theory and clinical treatment. A number of scientific and technological results have been transformed into productive forces. TCM education has formed a rational pattern based on inheriting traditional way of transmission from master to disciple as well as taking the university and college education as the main part. Minority medical science has been further explored and sorted out; the level of medical treatment, teaching and scientific research for ethnic minority medicines has been improved. As the contingent of integrated traditional and western medicine is growing steadily, medical treatment system, scientific research system and teaching system for integrated traditional and western medicine takes shape progressively. International exchange and cooperation on traditional Chinese medicine has been greatly promoted. Various forms of

  16. GAP - A Milestone in Traditional Chinese Medicine Production

    Institute of Scientific and Technical Information of China (English)

    MENGJIE; YUJIE

    2004-01-01

    IT is clear that in order for TCM (Traditional Chinese Medicine) production to meet world standards and enter the international market, herb plantation in China must be standardized. In late September 2003, the US FDA(Food and Drug Administration)held a seminar on the standardization of TCM development and quality control. It reached the conclusion that as long as the Chinese medicine production process meets GAP (Good Agricultural Practice,meaning standardized herbal material plantation), GLP (Good Laboratory Practice, meaning standardized experimental research)and GMP (Good Manufacturing Practice, meaning standardized extraction and preparation technology) standards, TCM products merit certification.

  17. Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy

    OpenAIRE

    Xuanbin Wang; Yibin Feng; Ning Wang; Fan Cheung; Hor Yue Tan; Sen Zhong; Charlie Li; Seiichi Kobayashi

    2014-01-01

    Chinese medicines have long history in treating cancer. With the growing scientific evidence of biomedical researches and clinical trials in cancer therapy, they are increasingly accepted as a complementary and alternative treatment. One of the mechanisms is to induce cancer cell death. Aim. To comprehensively review the publications concerning cancer cell death induced by Chinese medicines in recent years and provide insights on anticancer drug discovery from Chinese medicines. Materials and...

  18. The Transmission of Chinese Medicine in Australia

    Directory of Open Access Journals (Sweden)

    Mary Garvey

    2011-12-01

    Full Text Available The paper explores some of the issues concerning the transmission of Chinese medicine in Australia, its practitioner training and the future of Chinese medicine as a distinct medical discipline in the Australian context. In China over the last century Chinese medicine was overhauled in order to align it with the biomedical perspective prevalent in the West. These changes, in turn, had important consequences for the transmission of CM in Australia and the West. But while the biomedicalisation of CM has offered the path of least resistance, it has also lead to unworkable simplifications and methodological failures. The paper thus argues for a renewed access to the tradition’s primary sources in order to ally the distinctive features and methods of traditional practice with biomedicine, as an alternative to an outright integration into biomedical practice.

  19. Chinese herbal medicine research in eczema treatment

    Directory of Open Access Journals (Sweden)

    Leung Ping

    2011-04-01

    Full Text Available Abstract Eczema is a chronic relapsing atopic dermatitis (AD associated with pruritus, sleep disturbance and poor quality of life of the patient. Treatment of eczema includes use of emollient, topical and systemic antimicrobial agents, corticosteroid or immunomodulating agents. Many patients also seek alternative treatments such as dietary avoidance, supplementation or both. This article reviews the basic pathophysiology of eczema and clinical trials involving Chinese medicine in the treatment of eczema. Research reports on Chinese herbal medicine for eczema were retrieved from PubMed and the Cochrane Database for Systematic Reviews for this review. Only a few RCTs demonstrated the efficacy (or lack of efficacy of Chinese medicinal herbs in treating atopic eczema. Further larger scale trials are warranted.

  20. Chinese herbal medicine for treatment of dislipidemia

    Institute of Scientific and Technical Information of China (English)

    Haiyun Wu; Jianwei Bei; Jiao Guo

    2009-01-01

    Prevalence of dislipidemia is increasing rapidly in China and there has been a growing interest in Chinese herbal medicine for the treatment of hyperlipidemia both inside and outside China. In this article, lipids regulating effects of 9 herbs or their extracts and 5 herbal formulae which have been published in English-language literature are reviewed. Although evidence from animals and humans consistently supports the therapeutic activities of these Chinese herbal medicines, few multi-center large-scale clinical trials have been conducted to confirm the efficacy and evaluate their safety.

  1. [Scientific Positioning of Traditional Chinese Medicine].

    Science.gov (United States)

    Li, Yong-ming

    2016-03-01

    Whether traditional Chinese medicine (TCM) could be categorized as a kind of science or not has been a controversial issue over last century. Part of the confusion is caused by the indistinguishable usage of Chinese words "science" and "scientific" during discussion. According to western academic standards, TCM cannot be considered as pure or conventional science. However, in author's view, the foundation of a majority part of TCM practice is probably scientific, while many TCM theories remain unproved. In this article, medical theories and practices are classified based on scientific content into eight levels: medical science, scientific medicine, medical system, medical theory, medical opinion, medical belief, medical cultism, and medical fraud. Both Western medicine and TCM are positioned in this system accordingly. Currently, the scientific level of TCM is much lower than that of Western medicine, and more research is needed for its improvement.

  2. [Chinese Medicine in Overall Modern Scientific Technologies].

    Science.gov (United States)

    Tan, Yuan-sheng; Zeng Yong

    2015-10-01

    Chinese medicine (CM) develops with the survival, reproduction, growth, and progressing of the Chinese nation. Scientific technologies not only promote continual progressing of human societies, but also provide new ideas and methods for the development of CM. In recent years, great changes have taken place in CM complying with developing modern scientific technologies, mainly manifested in the depth of CM theories at molecular levels, the combination of syndrome differentiation and disease identification, continuous innovation and development of clinical diagnosis and treatment techniques, diversified dosages of Chinese materia medica, the academic tendency of education patterns, occupational refinement, diversified medical practice modes, and so on. PMID:26677664

  3. Spectral Analysis of Chinese Medicinal Herbs Based on Delayed Luminescence.

    Science.gov (United States)

    Pang, Jingxiang; Zhu, Xiaoyan; Liu, Yanli; Fu, Jialei; Zhao, Xiaolei; Yang, Meina; van Wijk, Eduard; Wang, Mei; Nie, Xiaoyan; Han, Jinxiang

    2016-01-01

    Traditional Chinese medicine (TCM) plays a critical role in healthcare; however, it lacks scientific evidence to support the multidimensional therapeutic effects. These effects are based on experience, and, to date, there is no advanced tool to evaluate these experience based effects. In the current study, Chinese herbal materials classified with different cold and heat therapeutic properties, based on Chinese medicine principles, were investigated using spectral distribution, as well as the decay probability distribution based on delayed luminescence (DL). A detection system based on ultraweak biophoton emission was developed to determine the DL decay kinetics of the cold and heat properties of Chinese herbal materials. We constructed a mathematical model to fit the experimental data and characterize the properties of Chinese medicinal herbs with different parameters. The results demonstrated that this method has good reproducibility. Moreover, there is a significant difference (p cold and heat properties. This approach takes advantage of the comprehensive nature of DL compared with more reductionist approaches and is more consistent with TCM principles, in which the core comprises holistic views. PMID:27478482

  4. 运用电子鼻检测活血化瘀中药物质基础研究%Study on the Material Foundation of Stasis-removing Chinese Medicine by Electronic Nose Detection

    Institute of Scientific and Technical Information of China (English)

    王光耀; 盛良; 王兴华; 汪宇; Te Kian Keong; Teh Siew Hoon; Ooi Ciat Hui

    2015-01-01

    Objective: To investigate whether there is a common material basis among Chinese medicines with similar effects, and whether the electronic nose can be used to quantify the property of Chinese medicines. Methods: Twelve kinds of Chinese medicinal herbs, which have the effect of promoting blood circulation and removing blood stasis, were tested by electronic nose. Principal component analysis(PCA) and the characteristic fingerprint were analysed together with differential index di and discriminant index. Results: The 12 kinds of Chinese medicinal herbs with the function of promoting blood circulation and removing blood stasis had similar PCA map and characteristic fingerprint. Conclusion: The 12 kinds of Chinese medicines have a common material basis.%目的 探讨具有相同功效的中药材是否具有共同的物质基础,运用电子鼻能否对中药的药性进行初步量化.方法 运用电子鼻检测常用具有活血化瘀功效的12种中药材,分析其PCA图和特征指纹图谱的相似性,并通过差异指数和判别指数对其作用作进一步说明.结果 检测的12种具有活血化瘀功效的中药材具有相似的PCA图和特征指纹图谱.结论 12种活血化瘀的中药具有共同的物质基础.

  5. An integrated web medicinal materials DNA database: MMDBD (Medicinal Materials DNA Barcode Database

    Directory of Open Access Journals (Sweden)

    But Paul

    2010-06-01

    Full Text Available Abstract Background Thousands of plants and animals possess pharmacological properties and there is an increased interest in using these materials for therapy and health maintenance. Efficacies of the application is critically dependent on the use of genuine materials. For time to time, life-threatening poisoning is found because toxic adulterant or substitute is administered. DNA barcoding provides a definitive means of authentication and for conducting molecular systematics studies. Owing to the reduced cost in DNA authentication, the volume of the DNA barcodes produced for medicinal materials is on the rise and necessitates the development of an integrated DNA database. Description We have developed an integrated DNA barcode multimedia information platform- Medicinal Materials DNA Barcode Database (MMDBD for data retrieval and similarity search. MMDBD contains over 1000 species of medicinal materials listed in the Chinese Pharmacopoeia and American Herbal Pharmacopoeia. MMDBD also contains useful information of the medicinal material, including resources, adulterant information, medical parts, photographs, primers used for obtaining the barcodes and key references. MMDBD can be accessed at http://www.cuhk.edu.hk/icm/mmdbd.htm. Conclusions This work provides a centralized medicinal materials DNA barcode database and bioinformatics tools for data storage, analysis and exchange for promoting the identification of medicinal materials. MMDBD has the largest collection of DNA barcodes of medicinal materials and is a useful resource for researchers in conservation, systematic study, forensic and herbal industry.

  6. Latest Progress on Chinese Herbal Medicines

    Institute of Scientific and Technical Information of China (English)

    Tianjin Press of Chinese Herbal Medicines

    2010-01-01

    @@ Chinese Herbal Medicines (CHM) has been recently included in the Wanfang Database-Digital Periodical Group, China Academic Journals Integrated Online Database, Index of Copernicus (IC) in Poland, Chemical Abstracts Service (CAS) in USA, and Ulrich's Periodicals Directory domestically and abroad.

  7. Introducing Considerations in the Translation of Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    Sonya E.Pritzker; Ka-Kit Hui

    2014-01-01

    This article introduces the document,Considerations in the Translation of Chinese Medicine, published in PDF form online in both Chinese and English. This 20-page document includes several sections describing why theConsiderations is necessary, the speciifcity of texts in Chinese medicine; the history of translation in Chinese medicine; who constitutes an ideal translator of Chinese medicine; what types of language exist in Chinese medicine; and speciifc issues in the translation of Chinese medicine, such as domestication versus foreignization, technical terminology, period-speciifc language, style, polysemy, and etymological translation. The final section offers a brief advisory for consumers, and concludes with a call to further discussion, and action, specifically in the development of international collaborative efforts towards the creation of more rigorous guidelines for the translation of Chinese medicine. The current article provides an overview of several of these sections, and includes links to the original document.

  8. National semantic infrastructure for traditional Chinese medicine

    Institute of Scientific and Technical Information of China (English)

    Hua-jun CHEN

    2012-01-01

    1 Introduction Traditional Chinese medicine (TCM) is "the traditional medicine that originated in China,and is characterized by holism and treatment based on pattern identification/syndrome differentiation" (WHO,2007).In China,traditional medicine accounts for around 40% of all healthcare delivered;in the West,TCM is increasingly adopted by medical practitioners as a form of complementary and altemative medicine (CAM) (WHO,2002).Both in China and in the West,scientists are attempting to bring the ancient heritage of TCM into line with modem standards,through the scientific development of TCM in the direction of evidence-based medicine (Qiu,2007).There is a pressing need for the digital preservation and global access of TCM knowledge assets.

  9. Study on international standard multilingual nomenclature of Chinese medicine.

    Science.gov (United States)

    Wang, Kui; Liu, Lu; Li, Wei; Shi, Da-zhuo; Zeng, Wen-ying; Zhu, Mian-sheng; Angles, Michel; Attali, Jean-Raymond; Choy, Pedro; Choy, Joao; Wu, Chi-haur; Zhai, Fu-han; Ramon, Maria Calduch; Chung, Ching

    2010-04-01

    The International Standard Chinese-English Basic Nomenclature of Chinese medicine (ISN) was released in 2007, a nomenclature list consisting of 6 500 Chinese medical terms. ISN was the culmination of several years of collaborative diligent work of over 200 specialists who represent Chinese medicine in 68 countries. The overall goal for devising standard English nomenclature for Chinese medicine is to develop a practical international standard nomenclature for Chinese medical basic terms, to make it compatible with contemporary research and educational standards in the globalized health care service. In this article, provided is an overview of principles and methods for the multilingual translations, the processes behind the particular content of the Chinese-English ISN and an introduction to the ongoing new projects, i.e. the multilingual versions of ISN (International Standards of Chinese-Spanish, Chinese-French and Chinese-Portuguese Basic Nomenclature of Chinese Medicine).

  10. [Study on determination of Chinese medicine flavor and its regularity].

    Science.gov (United States)

    Zhang, Zhuo; Zhang, Wei

    2014-02-01

    Five flavors are basic nature of Chinese medicine. But the labeling of Chinese medicine flavors was in a chaos. Song Jin and Yuan dynasty is a transconformation stage of labeling Chinese medicine flavors. In this article the author put forward that the determination of Chinese medicine flavor shifted from tasting of early and middle age of Northern Song dynasty to categorical analogizing and functional analogizing in the late age of Northern Song dynasty. The latter method had a flourished development in Southern Song, Jin and Yuan dynasty. This regularity conclusion has provided a reference for the standardizing Chinese medicine flavors. PMID:24946566

  11. Sasang Constitutional Medicine and Traditional Chinese Medicine: A Comparative Overview

    Directory of Open Access Journals (Sweden)

    Junghee Yoo

    2012-01-01

    Full Text Available Sasang constitutional medicine (SCM is a holistic typological constitution medicine which balances psychological, social, and physical aspects of an individual to achieve wellness and increase longevity. SCM has the qualities of preventative medicine, as it emphasizes daily health management based on constitutionally differentiated regimens and self-cultivation of the mind and body. This review's goal is to establish a fundamental understanding of SCM and to provide a foundation for further study. It compares the similarities and differences of philosophical origins, perspectives on the mind (heart, typological systems, pathology, and therapeutics between SCM and traditional Chinese medicine (TCM. TCM is based on the Taoist view of the universe and humanity. The health and longevity of an individual depends on a harmonious relationship with the universe. On the other hand, SCM is based on the Confucian view of the universe and humanity. SCM focuses on the influence of human affairs on the psyche, physiology, and pathology.

  12. [Inheritance and innovation of traditional Chinese medicinal authentication].

    Science.gov (United States)

    Zhao, Zhong-zhen; Chen, Hu-biao; Xiao, Pei-gen; Guo, Ping; Liang, Zhi-tao; Hung, Fanny; Wong, Lai-lai; Brand, Eric; Liu, Jing

    2015-09-01

    Chinese medicinal authentication is fundamental for the standardization and globalization of Chinese medicine. The discipline of authentication addresses difficult issues that have remained unresolved for thousands of years, and is essential for preserving safety. Chinese medicinal authentication has both scientific and traditional cultural connotations; the use of scientific methods to elucidate traditional experience-based differentiation carries the legacy of Chinese medicine forward, and offers immediate practical significance and long-term scientific value. In this paper, a path of inheritance and innovation is explored through the scientific exposition of Chinese medicinal authentication, featuring a review of specialized publications, the establishment of a Chinese medicine specimen center and Chinese medicinal image databases, the expansion of authentication technologies, and the formation of a cultural project dedicated to the Compedium of Materia Medica. PMID:26978977

  13. Integration of Traditional Chinese Medicine and modern medicine promotes the unification of human medicine

    Directory of Open Access Journals (Sweden)

    Peng Zhang

    2010-10-01

    Full Text Available "nThere are two mutually supportive systems in medical profession: modern medicines and traditional medicine. The current status is that although the modern medicine occupies the major position in healthcare system, the therapeutic effect of traditional medicines should not be omitted. If all of them merged and unified as one, it will be beneficial to the development of human medicine. In this paper, the integration of Traditional Chinese Medicine (TCM and modern medicine was exemplified to elucidate the mutual complements, mutual benefits of traditional medicines and modern medicine to maintain the unification of human medicine via the development of molecular biology, cytology etc. We believed that TCM theory may share the same mechanism with western medicine at some extent which need to be explored in the future research. In our point of view, although the road may twist and turn, the results are promising.

  14. Theory of traditional Chinese medicine and therapeutic method of diseases

    Institute of Scientific and Technical Information of China (English)

    Ai-Ping Lu; Hong-Wei Jia; Cheng Xiao; Qing-Ping Lu

    2004-01-01

    Traditional Chinese medicine, including herbal medicine and acupuncture, as one of the most important parts in complementary and alternative medicine (CAM), plays the key role in the formation of integrative medicine. Why do not the modern drugs targeting the specificity of diseases produce theoretical effects in clinical observation? Why does not the traditional Chinese medicine targeting the Zheng (syndrome) produce theoretical effects in clinic?There should have some reasons to combine Western medicine with Chinese herbal medicine so as to form the integrative medicine. During the integration, how to clarify the impact of CAM theory on Western medicine has become an emergent topic. This paper focuses on the exploration of the impact of theory of traditional Chinese medicine on the therapy of diseases in Western medicine.

  15. [Cultural anthropology of traditional Chinese medicine].

    Science.gov (United States)

    Wan, Xia; Liu, Jian-ping; Ai, Yan-ke; Li, Liu-ji

    2008-07-01

    Biological, psychological and sociological model of medicine substantializes the old model lacking the social humane attributes. The new medical model makes people take medical anthropology into research and highly evaluate traditional medical system. Cultural anthropology of traditional Chinese medicine (TCM) is part of medical anthropology with three major characteristics: wide research scope, specificity, and integration. It has developed its own research methods, such as field investigation, comprehensive inspection and comparison study. Cultural anthropology provides an efficient research method for TCM, and its application would further develop TCM theory and form comprehensive evaluation on TCM effects.

  16. Comparison of Traditional Chinese Medicine with Western Medicine Cancer Therapy

    Institute of Scientific and Technical Information of China (English)

    Linlin Gao; Xiongzhi Wu

    2008-01-01

    The interactions among drugs, tumor and host are critical for a response to therapy and for outcome. Anticancer herbs used in Chinese medicine are classified into 4 groups based on their target (tumor, patient and drug) as follows: eliminating pathogenic factors, strengthening the body resistance, enhancing effects of chemotherapy and detoxication of chemotherapy. Correspondingly, anticancer drugs used in Western medicine can be classified into 4 groups as follows: cytotoxic drugs, biological response modifiers, chemosensitizers and chemoprotectants.Based on the theory 0f Chinese medicinal formulas, prescriptions are composed of four constituents,namely,primary constituent(main component of the formula prescription),minister constituent(second component of formula prescription),adjuvant constituent(adjuvant component of the formula prescription)and messenger constituent(component making the formula prescription targeting pathological tissues).To control the interaction among drugs and to modulate the interaction among the tumor,patient and drugs,we suggest that combined therapy for Western medicine might include 4 constituent,i.e.,primary,cooperative,adjuvant and modulatory constituent.Cytotoxic dru gs frequently are used as primary and cooperative constituents.Whereas biological response modifiers and biochemical modu lators are usu ally regarded respectively as adjuvant drugs and modulatory constituents.We believe these new concepts may be helpful for the aim of appropriately designing.evaluating or providing combination therapy.

  17. The use of orchids in Chinese medicine

    OpenAIRE

    Bulpitt, Christopher J.; Li, Yan; Bulpitt, Pauline F; Wang, Jiguang

    2007-01-01

    In this article, the therapeutic uses of five Chinese medicines that contain orchids are discussed, together with a brief report of some of the animal experimentation undertaken. The impression that these preparations have no therapeutic use may be incorrect. However, herbal preparations have not usually been subject to the rigorous characterization and standardization necessary for clinical study, and persuading practitioners that substances in use for many centuries still need to be tested ...

  18. Proteomics and syndrome of Chinese medicine

    OpenAIRE

    Lu, Chuan-li; Qv, Xiao-Ying; Jiang, Jian-Guo

    2010-01-01

    Abstract Syndrome of Chinese medicine is an understanding of the regularity of disease occurrence and development and its performance of symptoms. Syndrome is the key to recognize diseases and the foundation to treat them. However, because of the complexity of the concept and the limitation of present investigations, the research of syndrome is hard to go further. Proteomics has been received extensive attention in the area of medical diagnosis and drug development. In the holistic and system...

  19. Traditional Chinese Medicine Induced Liver Injury

    OpenAIRE

    Teschke, Rolf

    2014-01-01

    Traditional Chinese Medicine (TCM) is popular around the world and encompasses many different practices with particular emphasis on herbal TCM. Using the PubMed database, a literature search was undertaken to assess the extent herbal TCM products exert rare hepatotoxicity. Analysis of reported cases revealed numerous specified herbal TCM products with potential hepatotoxicity. Among these were An Shu Ling, Bai Fang, Bai Xian Pi, Ban Tu Wan, Bo He, Bo Ye Qing Niu Dan, Bofu Tsu Sho San, Boh Gol...

  20. Cardiovascular Disease, Mitochondria, and Traditional Chinese Medicine

    OpenAIRE

    Jie Wang; Fei Lin; Li-li Guo; Xing-jiang Xiong; Xun Fan

    2015-01-01

    Recent studies demonstrated that mitochondria play an important role in the cardiovascular system and mutations of mitochondrial DNA affect coronary artery disease, resulting in hypertension, atherosclerosis, and cardiomyopathy. Traditional Chinese medicine (TCM) has been used for thousands of years to treat cardiovascular disease, but it is not yet clear how TCM affects mitochondrial function. By reviewing the interactions between the cardiovascular system, mitochondrial DNA, and TCM, we sho...

  1. Evidence-Based Chinese Medicine for Hypertension

    Directory of Open Access Journals (Sweden)

    Jie Wang

    2013-01-01

    Full Text Available Hypertension is an important worldwide public -health challenge with high mortality and disability. Due to the limitations and concerns with current available hypertension treatments, many hypertensive patients, especially in Asia, have turned to Chinese medicine (CM. Although hypertension is not a CM term, physicians who practice CM in China attempt to treat the disease using CM principles. A variety of approaches for treating hypertension have been taken in CM. For seeking the best evidence of CM in making decisions for hypertensive patients, a number of clinical studies have been conducted in China, which has paved the evidence-based way. After literature searching and analyzing, it appeared that CM was effective for hypertension in clinical use, such as Chinese herbal medicine, acupuncture, moxibustion, cupping, qigong, and Tai Chi. However, due to the poor quality of primary studies, clinical evidence is still weak. The potential benefits and safety of CM for hypertension still need to be confirmed in the future with well-designed RCTs of more persuasive primary endpoints and high-quality SRs. Evidence-based Chinese medicine for hypertension still has a long way to go.

  2. Chinese New Year Materials for Elementary Teachers.

    Science.gov (United States)

    Kwok, Irene

    This is a resource book designed to be used by teachers in Chinese bilingual bicultural programs. The materials in the book are based on Chinese New Year customs still observed in Chinese-American communities. The resource book contains five types of materials: (1) a general introduction to the Chinese New Year, including the Chinese Lunar Year…

  3. Opening up a Way of Evaluating Evidence-based Medicine in Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Evidence-based medicine is an authoritative way of evaluating the clinical efficacy of drugs, which provides the direct evidence for clinical medication. The rise of evidence-based medical research brought about the changes in Chinese medicine from the empirical medical era into the era of evidence-based medicine. Chinese medicine, as the experience

  4. [Identification of ancient Chinese medicinal specimens preserved at Natural History Museum in London].

    Science.gov (United States)

    Zhao, Zhong-zhen; Zhao, Kai-cun; Brand, Eric

    2015-12-01

    On-site field investigation was conducted to authenticate a batch of ancient Chinese medicinal decoction pieces that have been preserved in a rare collection at the Natural History Museum in London. These treasured artifacts comprise a portion of the Sloane Collection, and the nearly one hundred Chinese medicinal specimens examined within provide an objective record of the real situation regarding the Chinese medicinal materials in commercial circulation three hundred years ago. The precious data from this collection pro-vides an extremely valuable reference for the research into the history of medicinal exchange between China and the West during the Age of Exploration, shedding light on the evolution and historical changes in the species used in Chinese medicine, as well as the history of medicinal processing and decoction pieces.

  5. Progress of Research in Antitumor Mechanisms with Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    韩淑燕; 李萍萍

    2009-01-01

    The anti-tumor effects of Chinese herbal medicines and their prescription preparations attracted more and more attention at home and abroad.Thus,it is becoming a hot research topic to exploit the anti-tumor mechanisms of Chinese medicine,and some of them have been partly clarified with the improved research ability to date.In brief,the Chinese herbal medicines possess unique advantages on the treatment of tumors through their multiple actions on multiple targets.

  6. Latest Progress in Tianjin Press of Chinese Herbal Medicines

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    <正>Four journals including Chinese Traditional and Herbal Drugs (CTHD), Chinese Herbal Medicines (CHM), Drugs & Clinic (DC), and Drug Evaluation Research (DER) are edited and published by Tianjin Press of Chinese Herbal Medicines. CTHD was first published in 1970 and has been playing a great role for Chinese materia medica (CMM), especially in its present modernization. CTHD has successively won several honors in recent years, such as the 2nd State

  7. Thinking and practice of accelerating transformation of traditional Chinese medicine from experience medicine to evidence-based medicine.

    Science.gov (United States)

    Liu, Baoyan; Zhang, Yanhong; Hu, Jingqing; He, Liyun; Zhou, Xuezhong

    2011-06-01

    The gradual development of Chinese medicine is based on constant accumulation and summary of experience in clinical practice, but without the benefit of undergoing the experimental medicine stage. Although Chinese medicine has formed a systematic and unique theory system through thousands of years, with the development of evidence-based medicine, the bondage of the research methods of experience medicine to Chinese medicine is appearing. The rapid transition and transformation from experience medicine to evidence-based medicine have become important content in the development of Chinese medicine. According to the features of Chinese medicine, we propose the research idea of "taking two ways simultaneously," which is the study both in the ideal condition and in the real world. Analyzing and constructing the theoretical basis and methodology of clinical research in the real world, and building the stage for research technique is key to the effective clinical research of Chinese medicine. Only by gradually maturing and completing the clinical research methods of the real world could we realize "taking two ways simultaneously" and complementing each other, continuously produce scientific and reliable evidence of Chinese medicine, as well as transform and develop Chinese medicine from experience medicine to evidence-based medicine. PMID:21695621

  8. Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy

    Directory of Open Access Journals (Sweden)

    Xuanbin Wang

    2014-01-01

    Full Text Available Chinese medicines have long history in treating cancer. With the growing scientific evidence of biomedical researches and clinical trials in cancer therapy, they are increasingly accepted as a complementary and alternative treatment. One of the mechanisms is to induce cancer cell death. Aim. To comprehensively review the publications concerning cancer cell death induced by Chinese medicines in recent years and provide insights on anticancer drug discovery from Chinese medicines. Materials and Methods. Chinese medicines (including Chinese medicinal herbs, animal parts, and minerals were used in the study. The key words including “cancer”, “cell death”, “apoptosis”, “autophagy,” “necrosis,” and “Chinese medicine” were used in retrieval of related information from PubMed and other databases. Results. The cell death induced by Chinese medicines is described as apoptotic, autophagic, or necrotic cell death and other types with an emphasis on their mechanisms of anticancer action. The relationship among different types of cell death induced by Chinese medicines is critically reviewed and discussed. Conclusions. This review summarizes that CMs treatment could induce multiple pathways leading to cancer cell death, in which apoptosis is the dominant type. To apply these preclinical researches to clinic application will be a key issue in the future.

  9. Survey of investigations on Daodi Chinese medicinal materials in China since 1980s%中国道地药材研究20年概论

    Institute of Scientific and Technical Information of China (English)

    肖小河; 陈士林; 黄璐琦; 肖培根

    2009-01-01

    In the recent 20 years, three major investigational achievements about Daodi CMM (Chinese medicinal materials have been made as follows:① The herbal textual about Daodi CMM have been collected and revised systematically, and the causes and pattern of Daodi CMM formation and development were illustrated. ② A series of appraising methods and marks for Daodi CMM have been set up initially, the scientific connotation of Daodi CMM has been clarified primarily, which promotes the development of pharmacognosy discipline consequently.③Based on the Daodi CMM research program, the GAP of CMM with good quality, high yield and best benefit has been carried out elementarily, which is helpful to solve some economic problems and troubles which the peasant, countryside and agriculture always worry about. However, there are still some puzzles and misunderstandings about Daodi CMM to be treated with seriously. The main research aspects of Daodi CMM in the future could be focused on: ① Identification and authentication of the species and producing area of Daodi CMM. ② Establishment and implement of the commercial specification criterion of Daodi CMM. ③Standardization of the planting and processing technologies for Daodi CMM.%近20年来,我国道地药材研究取得了3个方面的主要进展:一是发掘和整理了道地药材本草资料,初步理清了道地药材形成的历史原因和规律;二是建立了一系列道地药材鉴定与评价方法,初步赋予道地药材现代科学内涵,推动了中药鉴定学和生药学发展;三是铺垫和推动了中药材GAP生产发展,促进中药材优质高产高效发展,促进农民创收和"三农"问题的解决.但是,当今道地药材研究尚存在一些问题和误区,道地药材品种和产地的认证认可、道地药材商品规格行业标准的制定和实施、道地药材规范化种植与加工等将是今后道地药材研究的重点领域和方向.

  10. [Technical standards of traditional Chinese medicine industry].

    Science.gov (United States)

    Wang, Guangping; Song, Jinqi

    2010-06-01

    Basing on the basic theory of traditional Chinese medicine (TCM), the technical standards of TCM industry is such a Link that it is to clarify the internal relations between the basic theory of TCM and developing of TCM industry. This article analyzed several problems of technical standards of TCM industry, such as basic theory of TCM and standardization problem of TCM industry. Technical standards of TCM industry must receive the guidance of basic theory of TCM, so that it will promote the process of modernization and internationalization of TCM industry.

  11. [Treatment of senile diseases should prescribe Chinese patent medicine scientifically].

    Science.gov (United States)

    Zhao, Xin-Xiang

    2014-04-01

    Treatment of senile diseases by Chinese patent medicine should prescribe according to physiological and pathological specialty of the aged. It's necessary for treatment according to syndrome differentiation associating with the disease,reasonable combination of drugs avoiding adverse reactions,gentle medicine character but not fierce,small medicine quantity but not great, the use of Chinese patent medicine mild and tonic used properly but not excessively. PMID:24812911

  12. Chemometrics and modernization of traditional Chinese medicine

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Development of chromatographic fingerprinting and its related chemometric methods in the research of quality control of traditional Chinese medicines(TCMs) are discussed. The quality control methods for guarantying the authentication and stability of products and semi-products of TCMs are firstly assessed. The technique based on chromatographic fingerprinting is essentially a kind of high-through put and integral tools to explore the complexity of herbal medicines. In order to further control the comprehensive quality of TCMs,confirmation and identification of their important chemical components are necessary. Some new strategies are proposed to trace the chemical changes of chromatographic fingerprints both in product processing and/or after their administration by modern chromatographic techniques and chemometrics. Combined with systems biology and bioinformatics,it seems possible for one to reveal the working mechanism of TCMs and to further control their intrinsic quality comprehensively.

  13. Study on the irradiation decontamination of traditional Chinese medicines

    International Nuclear Information System (INIS)

    Traditional Chinese Medicines (TCMs) are natural products prepared from plants, minerals and animals, it is easy for contamination by microorganisms to occur; thus causing problems in complying with the requirements laid down for passing microbial limit tests. We selected some kinds of TCMs, including unprocessed materia medica, traditional Chinese patent medicine (TCPMs) and chemical constituents for irradiation by 60Co gamma ray and investigating the results in terms of microbiology, chemistry, pharmacology and toxicology. We found no evidence of changes in most of the tested items, which indicates that the irradiation method could be employed for decontamination of TCMs. However, some chemical constituents of unprocessed materia medica, such as gentiopicrin in Radix Gentianae Macrophyllae and 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in Radix Polygoni Multiflori, decomposed when these crude materials were irradiated with dose of 5kGy. Further study revealed that although the medicinal were altered by irradiation, the monomers of some of these chemical constituents were not affected. In addition to investigation of the items described above, the doses of irradiation were selected experimentally to ensure that, after irradiation, the TCMs passed the microbial limit tests described in the Chinese Pharmacopoeia. The lowest possible doses were used in order to avoid any impairment of the quality and clinical efficacy of the effective ingredients of the TCMs. (author)

  14. [Where will Chinese medicine disease names go?].

    Science.gov (United States)

    Su, Zhan-Qing

    2013-06-01

    The statistical survey of "Clinical Articles", one column of Journal of Traditional Chinese Medicine (24 volumes in total) showed that, of the 151 academic exploration on diseases, Western disease (WM) names were used in 145 articles, constituting 96.03% of the entire column. Obviously, Chinese medicine (CM) disease names were not basically used by CM physicians. Taking Chinese Internal Medicine (2nd edition), a national textbook for students in CM universities, as an example, we could find that the use of disease names was in a chaos logically, disease, syndrome, and symptom were not used clearly. In the general knowledge part, when mentioning a disease, the book sometimes used "disease", sometimes "disease-syndrome". In the classified parts, some diseases were simply named as "A or B syndrome", and when talking about a specific disease, it referred to the symptom-based disease as a kind of "disease-syndrome". Throughout the whole book, the disease names named after symptoms or heavily colored by symptoms amounted to 31, accounting for 59.6% of the listed 52 common diseases. In clinical practices, using CM disease names ran the risk of making wrong diagnosis or failing to diagnose patients in time, and therefore, leading to improper treatment or loss of treatment time. For critical diseases, these names can't reveal the serious situations and help to get rid of possible dangers. For chronic diseases, using these names can't lead to early recognition and prevention of diseases. Considering that CM disease names can't go with clinical practices, and lag behind the development of integrative medicine, the author suggested that we should borrow as many WM disease names as possible in CM, because when compared with CM, WM has a much clearer and more objective knowledge of the location, cause, mechanisms, diagnosis, treatment, and prevention of diseases. The classification and naming of diseases in WM is the result of negotiation of WHO and its member countries

  15. [Where will Chinese medicine disease names go?].

    Science.gov (United States)

    Su, Zhan-Qing

    2013-06-01

    The statistical survey of "Clinical Articles", one column of Journal of Traditional Chinese Medicine (24 volumes in total) showed that, of the 151 academic exploration on diseases, Western disease (WM) names were used in 145 articles, constituting 96.03% of the entire column. Obviously, Chinese medicine (CM) disease names were not basically used by CM physicians. Taking Chinese Internal Medicine (2nd edition), a national textbook for students in CM universities, as an example, we could find that the use of disease names was in a chaos logically, disease, syndrome, and symptom were not used clearly. In the general knowledge part, when mentioning a disease, the book sometimes used "disease", sometimes "disease-syndrome". In the classified parts, some diseases were simply named as "A or B syndrome", and when talking about a specific disease, it referred to the symptom-based disease as a kind of "disease-syndrome". Throughout the whole book, the disease names named after symptoms or heavily colored by symptoms amounted to 31, accounting for 59.6% of the listed 52 common diseases. In clinical practices, using CM disease names ran the risk of making wrong diagnosis or failing to diagnose patients in time, and therefore, leading to improper treatment or loss of treatment time. For critical diseases, these names can't reveal the serious situations and help to get rid of possible dangers. For chronic diseases, using these names can't lead to early recognition and prevention of diseases. Considering that CM disease names can't go with clinical practices, and lag behind the development of integrative medicine, the author suggested that we should borrow as many WM disease names as possible in CM, because when compared with CM, WM has a much clearer and more objective knowledge of the location, cause, mechanisms, diagnosis, treatment, and prevention of diseases. The classification and naming of diseases in WM is the result of negotiation of WHO and its member countries

  16. Protecting traditional knowledge of Chinese medicine: concepts and proposals.

    Science.gov (United States)

    Liu, Changhua; Gu, Man

    2011-06-01

    With the development of the knowledge economy, knowledge has become one of the most important resources for social progress and economic development. Some countries have proposed measures for the protection of their own traditional knowledge. Traditional Chinese medicine belongs to the category of intangible cultural heritage because it is an important part of Chinese cultural heritage. Today the value of traditional knowledge of Chinese medicine has been widely recognized by the domestic and international public. This paper discusses the definition of traditional knowledge of Chinese medicine and its protection, and evaluates research on its classification. We review the present status of the protection of traditional knowledge of Chinese medicine and tentatively put forward some possible ideas and methods for the protection of traditional knowledge of Chinese medicine. Our goal is to find a way to strengthen the vitality of traditional Chinese medicine and consolidate its foundation. We believe that if we could establish a suitable sui generis(sui generis is a Latin term meaning "of its own kind" and is often used in discussions about protecting the rights of indigenous peoples. Here we use it to emphasize the fact that protection of traditional knowledge of Chinese medicine cannot be achieved through existing legal means of protection alone due to its unique characteristics) system for traditional knowledge, a more favorable environment for the preservation and development of traditional Chinese medicine will ultimately be created. PMID:21695628

  17. Protecting traditional knowledge of Chinese medicine: concepts and proposals.

    Science.gov (United States)

    Liu, Changhua; Gu, Man

    2011-06-01

    With the development of the knowledge economy, knowledge has become one of the most important resources for social progress and economic development. Some countries have proposed measures for the protection of their own traditional knowledge. Traditional Chinese medicine belongs to the category of intangible cultural heritage because it is an important part of Chinese cultural heritage. Today the value of traditional knowledge of Chinese medicine has been widely recognized by the domestic and international public. This paper discusses the definition of traditional knowledge of Chinese medicine and its protection, and evaluates research on its classification. We review the present status of the protection of traditional knowledge of Chinese medicine and tentatively put forward some possible ideas and methods for the protection of traditional knowledge of Chinese medicine. Our goal is to find a way to strengthen the vitality of traditional Chinese medicine and consolidate its foundation. We believe that if we could establish a suitable sui generis(sui generis is a Latin term meaning "of its own kind" and is often used in discussions about protecting the rights of indigenous peoples. Here we use it to emphasize the fact that protection of traditional knowledge of Chinese medicine cannot be achieved through existing legal means of protection alone due to its unique characteristics) system for traditional knowledge, a more favorable environment for the preservation and development of traditional Chinese medicine will ultimately be created.

  18. Regional Comparative Advantages of Chinese Medicinal Materials Industry in Longnan City%陇南市中药材产业的区域比较优势分析

    Institute of Scientific and Technical Information of China (English)

    刘佳琪; 叶得明

    2009-01-01

    The comparative advantages of Longnan's Chinese medicinal materials production among the scope of China and Gansu Province and the comparative advantages of the nine counties among Longnan City were analyzed and calculated. The results indicated that the Chinese medicinal materials production in Longnan City and nine counties of long, an have significant comparative advantages compared to the average level of China and Gansu Province; there was an obvious regional difference in comparative advantages of nine counties among Longnan City, but these advantages were all derived from the scale comparative advantages, the efficiency comparative advantages was lower or as disadvantages. In the end, the strategies of sustainable development for Chinese medicinal materials industry in Longnan were proposed.%通过对陇南市中药材生产在全国、甘肃省范围的比较优势及9县在全市的比较优势进行计算分析,得出以下结论:陇南市整体上及9县的中药材生产与全国和甘肃省的平均水平相比存在着显著的比较优势,9县在陇南市的比较优势也存在明显的区域差异,且优势均主要来源于规模比较优势,效率比较优势较低或处于劣势.并提出陇南市中药材产业可持续发展的对策建议.

  19. Evaluation of Antioxidant and Antimicrobial Activities from 28 Chinese Herbal Medicines

    OpenAIRE

    Ho-Yang Lin; Li-Yeh Chuang; Hsueh-Wei Chang; Cheng-Hong Yang

    2013-01-01

    Background: Many Chinese medicines have been reported to exhibit high antimicrobial and antioxidantactivities. In this study, 28 traditional Chinese herbal medicines were tested for their antioxidant and antibacterial activities.Materials and Methods: Total flavonoid content of the ethanol extracts were determined by a colorimetric method. Total phenol content was estimated as gallic acid equivalents. The antioxidant activities of the extracts were evaluated by various antioxidant assays, inc...

  20. Chinese herbal medicine for severe acute respiratory syndrome

    DEFF Research Database (Denmark)

    Liu, Jianping; Manheimer, Eric; Shi, Yi;

    2004-01-01

    To review randomized controlled trials (RCTs) evaluating the effects of Chinese herbal medicine for treating severe acute respiratory syndrome (SARS) systematically.......To review randomized controlled trials (RCTs) evaluating the effects of Chinese herbal medicine for treating severe acute respiratory syndrome (SARS) systematically....

  1. Chinese Medicine: A Cognitive and Epistemological Review

    Directory of Open Access Journals (Sweden)

    Ben Kavoussi

    2007-01-01

    Full Text Available In spite of the common belief that Chinese natural philosophy and medicine have a unique frame of reference completely foreign to the West, this article argues that they in fact have significant cognitive and epistemic similarities with certain esoteric health beliefs of pre-Christian Europe. From the standpoint of Cognitive Science, Chinese Medicine appears as a proto-scientific system of health observances and practices based on a symptomological classification of disease using two elementary dynamical-processes pattern categorization schemas: a hierarchical and combinatorial inhibiting–activating model (Yin-Yang, and a non-hierarchical and associative five-parameter semantic network (5-Elements/Agents. The concept-map of the five-parameter model amounts to a pentagram, a commonly found geomantic and spell casting sigil in a number of pre-Christian health and safety beliefs in Europe, to include the Pythagorean cult of Hygieia, and the Old Religion of Northern Europe. This non-hierarchical pattern-recognition archetype/prototype was hypothetically added to the pre-existing hierarchical one to form a hybrid nosology that can accommodate for a change in disease perceptions. The selection of five parameters rather than another number might be due to a numerological association between the integer five, the golden ratio, the geometry of the pentagram and the belief in health and wholeness arising from cosmic or divine harmony. In any case, this body of purely empirical knowledge is nowadays widely flourishing in the US and in Europe as an alternative to Western Medicine and with the claim of being a unique, independent and comprehensive medical system, when in reality it is structurally—and perhaps historically—related to the health and safety beliefs of pre-Christian Europe; and without the prospect for an epistemological rupture, it will remain built upon rudimentary cognitive modalities, ancient metaphysics, and a symptomological view of

  2. The quest for modernisation of traditional Chinese medicine

    OpenAIRE

    Xu, Qihe; Bauer, Rudolf; Hendry, Bruce M.; Fan, Tai-Ping; Zhao, Zhongzhen; Duez, Pierre; Simmonds, Monique SJ; Witt, Claudia M.; Lu, Aiping; Robinson, Nicola; Guo, De-an; Hylands, Peter J.

    2013-01-01

    Abstract Traditional Chinese medicine (TCM) is an integral part of mainstream medicine in China. Due to its worldwide use, potential impact on healthcare and opportunities for new drug development, TCM is also of great international interest. Recently, a new era for modernisation of TCM was launched with the successful completion of the Good Practice in Traditional Chinese Medicine Research in the Post-genomic Era (GP-TCM) project, the European Union’s Seventh Framework Programme (FP7) ...

  3. The compatibility of patent law and traditional Chinese medicine

    OpenAIRE

    Chen, Yifu; 陈一孚

    2013-01-01

    Traditional Chinese Medicine (TCM) is a medical system with a unique medical philosophy that continues to guide the contemporary turning out of new pharmaceutical formulae. The clinically-proved effective components of these formulae are being extracted by means of modern technology. Natural Chinese medicines account for approximately 30% of the global sales volume of all medicines, and the international market-size of the TCM industry is increasing rapidly. The TCM industry depends on the p...

  4. [Theoretical model for compatibility of medicinal property combination of traditional Chinese medicines].

    Science.gov (United States)

    Sun, Jing; Zhang, Yan-ling; Gu, Hao; Wang, Yun

    2015-08-01

    Medicinal properties are specific attributes of traditional Chinese medicines(TCM). The medicinal property theory is an important principle for the compatibility of traditional Chinese medicines. In this paper, medicinal properties, flavors and meridian tropism were combined to represent TCM medicinal properties; and multiple medicinal properties were further combined into medicinal property combination modes. TCMs and medicinal property combination modes were divided according to their efficacies, which were regarded as the concept of inductive logic programming and finally got medicinal property combination and compatibility rules with different efficacies. These medicinal property combination and compatibility rules were used to form the theoretical model through the entity grammar system, realize the automatic reasoning process from the medicinal property combination and compatibility to the efficacies, verify the reasoning result and analyze their rationality and limitations, in order to provide new ideas for revealing the relations between the TCM compatibility rules and efficacies. PMID:26790316

  5. Cardiovascular Disease, Mitochondria, and Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Jie Wang

    2015-01-01

    Full Text Available Recent studies demonstrated that mitochondria play an important role in the cardiovascular system and mutations of mitochondrial DNA affect coronary artery disease, resulting in hypertension, atherosclerosis, and cardiomyopathy. Traditional Chinese medicine (TCM has been used for thousands of years to treat cardiovascular disease, but it is not yet clear how TCM affects mitochondrial function. By reviewing the interactions between the cardiovascular system, mitochondrial DNA, and TCM, we show that cardiovascular disease is negatively affected by mutations in mitochondrial DNA and that TCM can be used to treat cardiovascular disease by regulating the structure and function of mitochondria via increases in mitochondrial electron transport and oxidative phosphorylation, modulation of mitochondrial-mediated apoptosis, and decreases in mitochondrial ROS. However further research is still required to identify the mechanism by which TCM affects CVD and modifies mitochondrial DNA.

  6. [A brief history of traditional Chinese medicinal pills].

    Science.gov (United States)

    Xu, X; Lu, X; Zhu, J P

    2016-05-01

    Traditional Chinese medicine pill, an archaic medicinal preparation form, is a kind of spherical or spherical-like preparation form produced by medicinal powders or extracts mixed with appropriate excipient or other accessories. It was originated in the Pre-Qin Dynasty, developed and enriched from the Han Dynasty to the Ming and Qing Dynasties. With the improvement of preparing process, honeyed pill, waxed pill, coating pill and wax-coating pill etc. appeared in succession. In modern times, with the progress of pharmaceutical machine, the medicinal pill is innovated constantly, and at present, it becomes the main form of Chinese patent medicine with batch production. PMID:27485865

  7. [The apprentice education system of Chinese medicinal industry in modern Kunming].

    Science.gov (United States)

    Yang, Zhuqing

    2015-07-01

    In the late Qing Dynasty, following the appearance of the Chinese medicinal materials industry trade association of Kunming, the "master agreement" as a professional regulation, also implemented, marking the beginning of the contractualization and institutionalization of apprentice education in Yunnan. The contents and implementation of the "master agreement" was organized by the Chinese medicinal materials industry trade association of Kunming and its craft union. The apprentice education in Kunming traditional Chinese medicinal industry has the following characteristics: expanding the source of talent; adepting at agricultural production of the accorded apprentice; conforming to the conditions of human manipulation of Chinese traditional medicine; being in line with the characteristics and rules of Chinese medicine skills taught by oral narration and tacit understanding; unity of the medical and pharmaceutical professionals; and non-governmental organization. Apprentice training had trained a number of medical talents, and promoted the transformation of manual workshop to industrialization in Kunming. Apprentice education had catalyzed the establishment of specialized shops selling patent medicines exclusively to separated from those running both crude drugs and patent medicines, to form a set of effective teaching system, thus exerting profound influence on later generations. PMID:26815024

  8. Pharmacokinetics Applications of Traditional Chinese Medicines

    Institute of Scientific and Technical Information of China (English)

    Qiu-Ju Li; Ai-Hua Zhang; Hui Sun; Xi-Jun Wang

    2016-01-01

    Traditional Chinese medicine (TCM) has been widely used in many oriental countries for thousands of years and played an indispensable role in the prevention and treatment of diseases, especially the complicated and chronic ones. It is a very complex mixture containing hundreds or thousands of different components. Pharmacokinetic study on active constituents in TCM preparations is a good way for us to explain and predict a variety of events related to the efficacy and toxicity of TCM. In the drug discovery phases, pharmacokinetics is a key to guide medicinal chemists in the optimization process of a chemical series and to assist pharmacologists to design in vivo studies. To explore the potentially bioactive components in TCM, it is necessary to further study the in vivo pharmacokinetic characteristics of multiple absorbed components and find out the optical time-course behavior to providing more substantial research for new leads in drug discovery. Pharmacokinetics screening method could provide a reliable means of prospecting natural products in the search for new leads in drug discovery. This review summarizes the research progress of PK on TCM in the search for suitable lead compounds in recent years.

  9. Traditional Chinese Medicine for Chronic Fatigue Syndrome

    Directory of Open Access Journals (Sweden)

    Rui Chen

    2010-01-01

    Full Text Available More and more patients have been diagnosed as having chronic fatigue syndrome (CFS in recent years. Western drug use for this syndrome is often associated with many side-effects and little clinical benefit. As an alternative medicine, traditional Chinese medicine (TCM has provided some evidences based upon ancient texts and recent studies, not only to offer clinical benefit but also offer insights into their mechanisms of action. It has perceived advantages such as being natural, effective and safe to ameliorate symptoms of CFS such as fatigue, disordered sleep, cognitive handicaps and other complex complaints, although there are some limitations regarding the diagnostic standards and methodology in related clinical or experimental studies. Modern mechanisms of TCM on CFS mainly focus on adjusting immune dysfunction, regulating abnormal activity in the hypothalamic-pituitary-adrenal (HPA axis and serving as an antioxidant. It is vitally important for the further development to establish standards for ‘zheng’ of CFS, i.e. the different types of CFS pathogenesis in TCM, to perform randomized and controlled trials of TCM on CFS and to make full use of the latest biological, biochemical, molecular and immunological approaches in the experimental design.

  10. [Herbal textual research on origin and development of traditional Chinese medicine "duhuo" and "qianghuo"].

    Science.gov (United States)

    Shan, Feng; Yuan, Yuan; Hao, Jin-Da; Huang, Lu-Qi

    2014-09-01

    To clarify the origin and development of the traditional Chinese medicine "Duhuo" and "Qianghuo" with medicinal literatures. Medical literatures of past dynasties were analysed and combined with the modern material. The "Duhuo" in Herbal writing Shen Nong Ben Cao Jing include traditional Chinese medicine "Duhuo" and "Qianghuo", "Qianghuo" was separated from "Duhuo" due to the distinguish of clinical application. The origin of "Qianghuo" is Notopterygium incisum and N. forbesii, However, The origin of "Duhuo" is very complex, Angelica pubescens f. biserrata as authentic "Duhuo" was used from Song Dynasty. "Qianghuo" was originated from "Duhuo". PMID:25522638

  11. The remote supervisory and controlling experiment system of traditional Chinese medicine production based on Fieldbus

    Science.gov (United States)

    Zhan, Jinliang; Lu, Pei

    2006-11-01

    Since the quality of traditional Chinese medicine products are affected by raw material, machining and many other factors, it is difficult for traditional Chinese medicine production process especially the extracting process to ensure the steady and homogeneous quality. At the same time, there exist some quality control blind spots due to lacking on-line quality detection means. But if infrared spectrum analysis technology was used in traditional Chinese medicine production process on the basis of off-line analysis to real-time detect the quality of semi-manufactured goods and to be assisted by advanced automatic control technique, the steady and homogeneous quality can be obtained. It can be seen that the on-line detection of extracting process plays an important role in the development of Chinese patent medicines industry. In this paper, the design and implement of a traditional Chinese medicine extracting process monitoring experiment system which is based on PROFIBUS-DP field bus, OPC, and Internet technology is introduced. The system integrates intelligence node which gathering data, superior sub-system which achieving figure configuration and remote supervisory, during the process of traditional Chinese medicine production, monitors the temperature parameter, pressure parameter, quality parameter etc. And it can be controlled by the remote nodes in the VPN (Visual Private Network). Experiment and application do have proved that the system can reach the anticipation effect fully, and with the merits of operational stability, real-time, reliable, convenient and simple manipulation and so on.

  12. Summary of the 2008 Evidence-based Chinese Medicine(EBCM) Workshop

    Institute of Scientific and Technical Information of China (English)

    吴大嵘; 赖世隆; 杨显荣

    2009-01-01

    The 2008 Evidence-based Chinese Medicine (EBCM) Workshop,jointly organized by the International Society for Chinese Medicine/Editorial Board of Chinese Medicine(Macao) and the Guangdong Provincial Hospital of Chinese Medicine/ Second Affiliated Hospital of Guangzhou University of

  13. [Study on dosage form design for improving oral bioavailability of traditional Chinese medicines].

    Science.gov (United States)

    Xia, Hai-Jian; Zhang, Zhen-Hai; Yao, Dong-Dong; Jia, Xiao-Bin

    2013-09-01

    Both chemical drugs and traditional Chinese medicines have the problem of low bioavailability. However, as traditional Chinese medicines are a multi-component complex, their dosage forms are required to be designed in line with their characteristics, in order to improve the bioavailability of traditional Chinese medicines. Traditional Chinese medicines are mostly prepared into pill, powder, paste, elixir and decoction, but with such drawbacks as high administration dose and poor efficacy. With the process of modernization of traditional Chinese medicines, new-type preparations have be developed and made outstanding achievements. However, they fail to make an organic integration between traditional Chinese medicine theories and modern preparation theories. Characteristics of traditional Chinese medicines are required to be taken into account during the development of traditional Chinese medicines. In the article, multi-component preparation technology was adopted to establish a multi-component drug release system of traditional Chinese medicines on the basis of multiple components of traditional Chinese medicines.

  14. How does Chinese medicine target cytokine imbalance in rheumatoid arthritis?

    Science.gov (United States)

    Liu, Jian; Sun, Yue

    2013-11-01

    Rheumatoid arthritis (RA) manifests as an imbalance between pro- and anti-inflammatory cytokines. Cytokine imbalance is suggested to play critical roles in the development of RA. Currently, various treatments for RA, including biological agents such as antibodies against inflammation mediators, or Chinese herbal medicines, intervene the disease by restoring the balance of cytokines. Chinese medicine (CM) can not only suppress the expression of pro-inflammatory cytokines, but also induce the expression of cytokines with anti-inflammatory and immunomodulatory effects. Thus, Chinese medicine can effectively reduce inflammatory cell infiltration into synovial tissue, pannus formation, and degradation of the extracellular matrix surrounding cartilage cells, thereby reducing subchondral bone damage. This paper reviews the changes of cytokine profiling during development of RA and discuss the mechanisms by which Chinese medicine restores the cytokine balance.

  15. How does Chinese medicine target cytokine imbalance in rheumatoid arthritis?

    Science.gov (United States)

    Liu, Jian; Sun, Yue

    2013-11-01

    Rheumatoid arthritis (RA) manifests as an imbalance between pro- and anti-inflammatory cytokines. Cytokine imbalance is suggested to play critical roles in the development of RA. Currently, various treatments for RA, including biological agents such as antibodies against inflammation mediators, or Chinese herbal medicines, intervene the disease by restoring the balance of cytokines. Chinese medicine (CM) can not only suppress the expression of pro-inflammatory cytokines, but also induce the expression of cytokines with anti-inflammatory and immunomodulatory effects. Thus, Chinese medicine can effectively reduce inflammatory cell infiltration into synovial tissue, pannus formation, and degradation of the extracellular matrix surrounding cartilage cells, thereby reducing subchondral bone damage. This paper reviews the changes of cytokine profiling during development of RA and discuss the mechanisms by which Chinese medicine restores the cytokine balance. PMID:24170633

  16. Application of microdialysis technique in the traditional chinese medicine

    DEFF Research Database (Denmark)

    Zhang, Shaomin; Zeng, Xianghui; Xu, Xiaohong;

    2005-01-01

    The concentration of extracellular neurotransmitters can be dynamically measured by in vivo microdialysis. This technique can apply to quantitatively evaluating the beneficial effects of Traditional Chinese Medicine (TCM). In the present study, the protective effects of Puerarin (Pur) on cerebral...

  17. Computer-Mediated Materials for Chinese Character Learning.

    Science.gov (United States)

    Hsu, Hui-Mei; Gao, Liwei

    2002-01-01

    Reviews four sets of computer-mediated materials for Chinese character learning. These include the following: Write Chinese, Chinese Characters Primer, Animated Chinese Characters, and USC Chinese Character Page. (Author/VWL)

  18. Traditional Chinese Medicine for Senile Dementia

    Directory of Open Access Journals (Sweden)

    Zhihong Lin

    2012-01-01

    Full Text Available Traditional Chinese Medicine (TCM has a 3000 years' history of human use. A literature survey addressing traditional evidence from human studies was done, with key result that top 10 TCM herb ingredients including Poria cocos, Radix polygalae, Radix glycyrrhizae, Radix angelica sinensis, and Radix rehmanniae were prioritized for highest potential benefit to dementia intervention, related to the highest frequency of use in 236 formulae collected from 29 ancient Pharmacopoeias, ancient formula books, or historical archives on ancient renowned TCM doctors, over the past 10 centuries. Based on the history of use, there was strong clinical support that Radix polygalae is memory improving. Pharmacological investigation also indicated that all the five ingredients mentioned above can elicit memory-improving effects in vivo and in vitro via multiple mechanisms of action, covering estrogen-like, cholinergic, antioxidant, anti-inflammatory, antiapoptotic, neurogenetic, and anti-Aβ activities. Furthermore, 11 active principles were identified, including sinapic acid, tenuifolin, isoliquiritigenin, liquiritigenin, glabridin, ferulic acid, Z-ligustilide, N-methyl-beta-carboline-3-carboxamide, coniferyl ferulate and 11-angeloylsenkyunolide F, and catalpol. It can be concluded that TCM has a potential for complementary and alternative role in treating senile dementia. The scientific evidence is being continuously mined to back up the traditional medical wisdom.

  19. Traditional Chinese medicine in treatment of opiate addiction

    Institute of Scientific and Technical Information of China (English)

    Jie SHI; Yan-li LIU; Yu-xia FANG; Guo-zhu XU; Hai-fen ZHAI; Lin LU

    2006-01-01

    Traditional Chinese medicine (TCM) includes Chinese medicine and acupuncture. Chinese medicine consists of natural products including plants, animals and minerals. TCM has been practiced in China for more than 2000 years, and for the past 200 years has been used in treatment of drug addiction. Ten Chinese medicines for the treatment of opiate addiction have been approved by the Chinese State Food and Drug Administration (SFDA), and at least 6 are in clinical trials. The general therapeutic principle of Chinese medicine developed was based on its unique theory of "reinforcing healthy Qi and resolving and removing effects of toxicity". Acupuncture, another essential part of TCM, which was developed based on the principle that "functions of the human body are controlled by the 'Jing-Luo' and 'Qi-Xue' system", has been used not only in China, but also in Europe, the USA and other countries, for controlling opiate addiction. There are some advantages in using TCM for opiate detoxification, including less harmful side effects, high safety and ideal effects in the inhibition of protracted withdrawal symptoms and relapse. Co-administration of TCM with modern medicine shows some synergistic effects in detoxification. Many TCM for detoxification also have efficacy in the rehabilitation of abnormal body functions induced by chronic drug use, including improving immune function, increasing working memory and preventing neurological disorder. Given that TCM is effective in the prevention of relapse and causes fewer side effects, it may be used widely in the treatment of opiate addiction.

  20. THE NEW YEAR MESSAGE FROM CHINESE JOURNAL OF INTEGRATIVE MEDICINE

    Institute of Scientific and Technical Information of China (English)

    陈可冀

    2003-01-01

    @@ Two months into the year 2003 and one month into the Chinese lunar New Year of goat, on behalf of the editorial board of the Chinese Journal of Integrative Medicine, I wish our readers, contributors and board members around the world a prosperous and successful new year.

  1. Opening up a Way of Evaluating Evidence-based Medicine in Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    JIA Zhen-hua

    2009-01-01

    @@ dence-based medicine is an authoritative way of evaluating the clinical efficacy of drugs,which provides the direct evidence for clinical medication.The rise of evidence-based medical research brought about the changes in Chinese medicine from the empirical medical era into the era of evidence-based medicine.

  2. 武警部队执行地震救援中的药材保障%Medicinal materials guarantee of earthquake emergency medical relief team of the Chinese People’s Armed Police Forces

    Institute of Scientific and Technical Information of China (English)

    贺智; 安茜; 谢红; 郭海涛; 叶路

    2015-01-01

    Objective To develop a reasonable and scientific scheme for medicinal materials that disaster relief teams of the Chinese People’s Armed Police Forces (CPAPF) should carry in earthquake relief work. Methods The cases of disposition of medicinal materials of the disaster relief teams of the CPAPF in Wenchuan and Yushu Earthquake areas , 2008 and 2010 respectively, were investigated. The relevant disease spectra during the early periods of earthquake (within 3 days) were analyzed. In addition, literatrure review and expert counseling were used. According to the maximum outpatient quantity of 800 persons, the bases of medicinal materials needed for single appropriate medical skills were calculated based on the“Standard for the guarantee of military related medicines”and the“Standards of millitary matrerials of the Chinese Armed Police Forces”, and with the method of management of single disease cases. Thus the species of medicinal materials and quantities thererof necessary for the relief teams during the first 3 days after earthquake were determined . Results A detailed list of medicinal materials any relief team should carry during the first 3 days after earthquake, including 10 categories with 87 species, had been developed. Conclusion A reasonable and scientific scheme for medicinal materials carried by disaster relief teams of the CPAPF in earthquake relief work based on quantitative study has been made, thus providing a useful model for reference.%目的:为武警部队医学救援队携运药材制定合理、科学的药材保障配置方案。方法分析总结汶川和玉树地震救援中药材配置方面的现状,并根据地震早期伤病谱,采用文献调研法、以《军队相关药材保障标准》及《武警部队战材标准》为基本依据,借鉴单病种病例管理方法,同时结合救援专家建议,计算单项适宜医学治疗技术所需的药材保障基数,从而确定武警部队医学救援队

  3. M easurement on trace element composition of Chinese medicinal materials by laser-induced breakdow n spectroscopy%中药材微量元素成分的LIBS检测

    Institute of Scientific and Technical Information of China (English)

    董晨钟; 杨峰; 苏茂根

    2015-01-01

    利用时间分辨的激光诱导击穿光谱技术对中药材炒泽泻样品进行了检测分析,测得了样品中的Mg,Al,Si,P, Ca ,Ti ,Mn ,Fe ,Co和C等10种元素。基于等离子体局域热动力学平衡假设,得到了等离子体的电子密度和温度,最后利用自由定标分析方法得到了9种元素相对于C的含量。结果表明激光诱导击穿光谱技术可以用于中药材微量元素的有效快速检测。%Time‐resolved laser induced breakdow n spectroscopy is used to measure and analyze Oriental Water Plantain Rhizome which is a kind of Chinese medicinal material . Ten kinds of elemental composition in the sample , w hich are M g ,Al ,Si ,P ,Ca ,Ti ,M n ,Fe ,Co and C have been identified . Based on local thermodynamic equilibrium assumption , plasma temperature and electron number density are obtained , and the concentrations of the nine elements relative to the carbon have been estimated by calibration‐free method . The result of the experiment approved that laser induced breakdown spectroscopy can be applied to the rapid and effective detection on the trace element composition of Chinese medicinal materials .

  4. The Mechanism for the Effect of Chinese Medicine on Strait Episode of Complex Diseases.

    Science.gov (United States)

    Han, Jing-Yan

    2016-01-01

    Complex diseases always involve some strait episode, such as myocardial hypertrophy and fibrosis caused by hypertension, microcirculation dysfunction and injury in heart, brain, lever, and intestine following ischemia and reperfusion, endotoxin induced multiorgan injury, and recovery after intestinal mucosa damage, for which intervention by a single medicine remains unsatisfied in clinic.Chinese medicine has been applied in clinic for more than two thousand years, which presents as a healthcare system using compound formula preparation, treatment based on syndrome differentiation and individualization thus has advantage in dealing with strait episode of complex diseases. However, the mechanism underlying Chinese medicine is not fully understood up till now.This report will explain the mechanisms underlying the beneficial role of Chinese medicine in therapy of strait episode of complex diseases based on the resent outcomes in study of aforementioned complex diseases. The speaker, using the theory of blood stasis and activating blood to remove stasis in Chinese medicine, classified microcirculation dysfunction induced by different causes, such as ischemia and reperfusion, stress, LPS, common cold, investigated the pathogenesis and progressing of each of which. Furthermore, the report explored the material basis and mechanism for compound formula of Chinese medicine with potential of tonifying Qi and activating blood, removing heat to cool blood, identified the ingredient in the compound formula responsible for respective effect.(Presented at the 1920th Meeting, June 3, 2016). PMID:27349663

  5. Structure analysis of active components of traditional Chinese medicines

    DEFF Research Database (Denmark)

    Zhang, Wei; Sun, Qinglei; Liu, Jianhua

    2013-01-01

    Traditional Chinese Medicines (TCMs) have been widely used for healing of different health problems for thousands of years. They have been used as therapeutic, complementary and alternative medicines. TCMs usually consist of dozens to hundreds of various compounds, which are extracted from raw...

  6. [Application of ultrasound counter currentextraction in patent of traditional Chinese medicine].

    Science.gov (United States)

    Miao, Yan-ni; Wu, Bin; Yue, Xue-lian

    2015-07-01

    The patent information of ultrasound countercurrent extraction used in traditional Chinese medicine was analyzed in this paper by the samples from Derwent World Patent Database (DWPI) and the Chinese Patent Abstracts Database (CNABS). The application of ultrasound countercurrent was discussed with the patent applicant,the amount of the annual distribution, and the pharmaceutical raw materials and other aspects. While the technical parameters published in the patent was deeply analyzed, such as material crushing, extraction solvent, extraction time and temperature, extraction equipment and ultrasonic frequency. Thought above research, various technical parameters of ultrasound countercurrent extraction used in traditional Chinese was summarize. The analysis conclusion of the paper can be used in discovering the technical advantages, optimizing extraction conditions, and providing a reference to extraction technological innovation of traditional Chinese medicine.

  7. [Application of ultrasound counter currentextraction in patent of traditional Chinese medicine].

    Science.gov (United States)

    Miao, Yan-ni; Wu, Bin; Yue, Xue-lian

    2015-07-01

    The patent information of ultrasound countercurrent extraction used in traditional Chinese medicine was analyzed in this paper by the samples from Derwent World Patent Database (DWPI) and the Chinese Patent Abstracts Database (CNABS). The application of ultrasound countercurrent was discussed with the patent applicant,the amount of the annual distribution, and the pharmaceutical raw materials and other aspects. While the technical parameters published in the patent was deeply analyzed, such as material crushing, extraction solvent, extraction time and temperature, extraction equipment and ultrasonic frequency. Thought above research, various technical parameters of ultrasound countercurrent extraction used in traditional Chinese was summarize. The analysis conclusion of the paper can be used in discovering the technical advantages, optimizing extraction conditions, and providing a reference to extraction technological innovation of traditional Chinese medicine. PMID:26666026

  8. Traditional Chinese Medicine Induced Liver Injury.

    Science.gov (United States)

    Teschke, Rolf

    2014-06-01

    Traditional Chinese Medicine (TCM) is popular around the world and encompasses many different practices with particular emphasis on herbal TCM. Using the PubMed database, a literature search was undertaken to assess the extent herbal TCM products exert rare hepatotoxicity. Analysis of reported cases revealed numerous specified herbal TCM products with potential hepatotoxicity. Among these were An Shu Ling, Bai Fang, Bai Xian Pi, Ban Tu Wan, Bo He, Bo Ye Qing Niu Dan, Bofu Tsu Sho San, Boh Gol Zhee, Cang Er Zi, Chai Hu, Chaso, Chi R Yun, Chuan Lian Zi, Ci Wu Jia, Da Chai Hu Tang, Da Huang, Du Huo, Gan Cao, Ge Gen, Ho Shou Wu, Hu Bohe You, Hu Zhang, Huang Qin, Huang Yao Zi, Hwang Geun Cho, Ji Gu Cao, Ji Ji, Ji Xue Cao, Jiguja, Jin Bu Huan, Jue Ming Zi, Kamishoyosan, Kudzu, Lei Gong Teng, Long Dan Xie Gan Tang, Lu Cha, Ma Huang, Mao Guo Tian Jie Cai, Onshido, Polygonum multiflorum, Qian Li Guang, Ren Shen, Sairei To, Shan Chi, Shen Min, Shi Can, Shi Liu Pi, Shou Wu Pian, Tian Hua Fen, White flood, Wu Bei Zi, Xi Shu, Xiao Chai Hu Tang, Yin Chen Hao, Zexie, Zhen Chu Cao, and various unclassified Chinese herbal mixtures. Causality was firmly established for a number of herbal TCM products by a positive reexposure test result, the liver specific scale of CIOMS (Council for International Organizations of Medical Sciences), or both. Otherwise, the quality of case data was mixed, especially regarding analysis of the herb ingredients because of adulteration with synthetic drugs, contamination with heavy metals, and misidentification. In addition, non-herbal TCM elements derived from Agaricus blazei, Agkistrodon, Antelope, Bombyx, Carp, Fish gallbladder, Phellinus, Scolopendra, Scorpio, and Zaocys are also known or potential hepatotoxins. For some patients, the clinical course was severe, with risks for acute liver failure, liver transplantation requirement, and lethality. In conclusion, the use of few herbal TCM products may rarely be associated with hepatotoxicity in some

  9. Intercellular communication, NO and the biology of Chinese medicine

    Directory of Open Access Journals (Sweden)

    Ralt Dina

    2005-05-01

    Full Text Available Abstract New multiple categories of health disciplines have become popular in the west and integration between the medicinal approaches has become essential. The hypothesis presented here suggests a novel integrative view that combines Western biochemistry with the Chinese medicinal concept of qi. The core for this hypothesis is that transmission of qi along the meridians is based on informational molecules that travel via an intercellular communication system. Acupuncture at specific points enhances the flow of the signaling molecules through this communication system. Nitric oxide is suggested as a prime candidate for such a signaling molecule in the meridian system. The biochemistry of nitric oxide can shed light on the biology underlying Chinese medicine while Chinese medicinal data can provide a clue to the sought after framework for nitric oxide.

  10. Traditional Chinese and Thai medicine in a comparative perspective.

    Science.gov (United States)

    He, Ke

    2015-12-01

    The work presented in this paper compares traditional Chinese medicine and traditional Thai medicine, expounding on origins, academic thinking, theoretical system, diagnostic method and modern development. Based on a secondary analysis of available literature, the paper concentrates on two crucial historical developments: (1) the response to, and consequences of, the impact of the Western medicine; and (2) the revival of traditional medicine in these two countries and its prospects. From a comparative perspective, the analysis has led to the conclusion that the rise and fall of traditional medicine is an issue closely related with social and political issues; and the development of traditional medicines requires national policy and financial support from governments, human resource development, the improvement of service quality, and the dissemination of traditional medicine knowledge to the public. In addition, this paper also suggests deepening exchanges and cooperation between China and Thailand, strengthening cooperation between traditional medicine and medical tourism. PMID:26645523

  11. Study designs of randomized controlled trials not based on Chinese medicine theory are improper

    Directory of Open Access Journals (Sweden)

    Jiao Yan

    2009-02-01

    Full Text Available Abstract Current biomedical research methods to evaluate the efficacy of Chinese medicine interventions are often conceptually incompatible with the theory and clinical practice of Chinese medicine. In this commentary, we (1 highlight the theory and principles underlying Chinese medicine clinical practice; (2 use ginseng as an example to describe clinical indications in Chinese medicine; (3 propose a framework guided by Chinese medicine theory for the evaluation of study designs in Chinese medicine research; and (4 evaluate 19 randomized, double-blind, placebo-controlled trials of ginseng. Our analysis indicates that all 19 trials with both positive and negative results confirm the specific effects of ginseng indicated by Chinese medicine theory. Study designs guided by Chinese medicine theory are necessary to validate and improve future randomized controlled clinical trials in Chinese medicine.

  12. Contrast between Western Medicine and Traditonal Chinese Medicine on their application

    Institute of Scientific and Technical Information of China (English)

    管隽

    2011-01-01

    It appears that integrating traditional Chinese medicine with western medicine could be of benefit to solve medical problems or improve therapeutic effects.It is concluded that western medicine is more appropriate in treating some diseases which are acute,with a explicit cause,and single-system diseases while traditional Chinese medicine treatment can provide better results in treating some diseases especially which are chronic,without clear cause,and multi-system diseases.It seems possible that this discussion will highlight some diseases which need to be considered seriously to select more effective and reasonable treatments.

  13. New Progress in Modern Research on Chinese Herbal Medicines Published in Chinese Traditional and Herbal Drugs in 2010: Annual Highlights and Comments

    Institute of Scientific and Technical Information of China (English)

    HE Chun-nian; LIU Yan-ze; XIAO Pei-gen

    2011-01-01

    As a series of and continuous publication,the papers published on Chinese Traditional and Herbal Drugs in 2010 were selectively and briefly highlighted to reflect the new progress on modern research of Chinese herbal medicines.Within 617 articles,chemical constituents (127),pharmaceutics and technology (149),pharmacological studies and clinical observation,and medicinal materials are still major categories.Some comments have also been personally provided.

  14. Analysis on the Factors Influencing the Curative Effect of Chinese Patent Medicine%剖析影响中成药疗效的因素

    Institute of Scientific and Technical Information of China (English)

    陈昌钢

    2015-01-01

    The factors influencing the curative ef ect of Chinese traditional medicines are medicines variety and quality,Chinese herbal medicine quality of germplasm resources,Chinese herbal medicine planting cultivation and recovery processing,Chinese herbal medicine recovery processing,Chinese herbal medicine standardized cultivation,preparation technique,form,materials and making preparation, Chinese medicine compatibility between preparations.%影响中成药疗效的因素主要有中药材品种及质量、中药材种质资源质量、中药材种植栽培与采收加工、中药材采收加工、中药材规范化种植、炮制技术、剂型、辅料及制备工艺、中药成方制剂之间的配伍。

  15. Multi-disciplinary Research in Traditional Chinese Medicine--An Exploration

    Institute of Scientific and Technical Information of China (English)

    Mo Feizhi

    2005-01-01

    This paper discusses the present state of Traditional Chinese Medicine being divided into three leading lines of thought, namely, the Clinical line,the Integration of Western and Chinese Medicine line and the Development of Traditional Chinese Medicine line. It also describes the position of Traditional Chinese Medicine being a medical science rich in philosophy and wisdom and a culture centred upon medical science and technology. It outlines the basic characteristic of Traditional Chinese pointed out various flaws in methodology in Integration of Western and Chinese Medicine research. It also stresses that in order to make fruitful progress in the development of Traditional Chinese Medicine,multi-discipline research in Traditional Chinese Medicine should be made on a thoroughly understanding of the basic methodology of Traditional Chinese Medicine and follow its established principles.

  16. Globalization of Traditional Chinese Medicinal products And New Regulatory Structures in the European Union

    Institute of Scientific and Technical Information of China (English)

    Emiel Van Galen; Burt Kroes

    2009-01-01

    @@ Traditional Chinese Medicine (TCM) , Registration, EU pharmaceutical legislation, Traditional Herbal Medicinal Products, tHMP, quality, safety, efficacy, traditional use, EMEA, European Medicines Agency, European Pharmacopoeia, Herbal Medicinal Products Committee, HMPC, Community Monographs, Commu-nity List.

  17. Use of traditional Chinese medicine in the management of urinary stone disease

    Directory of Open Access Journals (Sweden)

    Ricardo Miyaoka

    2009-08-01

    Full Text Available Objective: To assess the evidence-based literature supporting the use of traditional Chinese medicine Kampo herbal and Acupuncture in stone disease management. Materials and Methods: Four of the most commonly used herbal components of Kampo medicine in the treatment of stone disease are described according to their in vitro and in vivo effects. We also reviewed the role of Acupuncture in urologic clinical setting as well as its proposed mechanisms of action and results. Medline database was assessed using isolated and conjugated key words (Chinese Medicine, Kampo, Chinese Herbal, Calculi, Stone Disease, Kidney, Acupuncture, Herbal Medicine. Articles were reviewed and summarized. Results: Herbal medicine has been proven to be free from side-effects and therefore suitable for long term use therapy. Its antilithic beneficial effects include increased urinary volume, increased magnesium excretion (Takusya, inhibitory activity on calcium oxalate aggregation (Takusya, Wulingsan and Desmodyum styracyfolium, inhibition of calcium oxalate nucleation and hydroxyapatite internalization (Wulingsan. In contrast, acupuncture, has shown to be effective as a pre-treatment anxiolytic and analgesic during colic pain and extracorporeal shock wave lithotripsy treatment, reducing the need for complementary sedative drugs. Conclusion: Chinese traditional medicine is promising as regards its role in stone prevention. An effort must be made in order to standardize study protocols to better assess acupuncture results since each procedure differs in regards to selected acupoints, electrostimulation technique and adjunct anesthetics. Similarly, standardization of Kampo formulations and acceptable clinical endpoints (imaging vs. symptomatic events is needed.

  18. Ayurveda and Traditional Chinese Medicine: A Comparative Overview

    Directory of Open Access Journals (Sweden)

    Bhushan Patwardhan

    2005-01-01

    Full Text Available Ayurveda, the traditional Indian medicine (TIM and traditional Chinese medicine (TCM remain the most ancient yet living traditions. There has been increased global interest in traditional medicine. Efforts to monitor and regulate herbal drugs and traditional medicine are underway. China has been successful in promoting its therapies with more research and science-based approach, while Ayurveda still needs more extensive scientific research and evidence base. This review gives an overview of basic principles and commonalities of TIM and TCM and discusses key determinants of success, which these great traditions need to address to compete in global markets.

  19. Incorporating pattern identification of Chinese medicine into precision medicine: An integrative model for individualized medicine.

    Science.gov (United States)

    Li, Jin-gen; Xu, Hao

    2015-11-01

    On 20 January, 2015, U.S. President Obama announced an ambitious plan called "Precision Medicine (PM) Initiative", aiming to deliver genetics-based medical treatments. PM has shown a promising prospect by tailoring disease treatments and preventions to individuals. However, a predominantly genetics-based method restricts its benefit and applicability in most chronic and complex diseases. Pattern identification (PI) is one of the representative characteristics of Chinese medicine implying the concept of holism and individualized treatment. It is another classification method taking environmental, psychosocial and other individual factors into account. Integrating PI with disease diagnosis of Western medicine will provide a strong complement to genetics-based PM, thus establish an integrative model for individualized medicine. PI provides new perspectives for PM, not only in clinical practice, but also in new drug development and clinical trial design. It is for sure that the integrative approach will ultimately lead to a safer, more convenient and effective patient-centered healthcare and most patients will benefit in the era of PM.

  20. Study on Analgesic Effect of Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    YU Shan; XU Ling; WEI Pin-kang; QIN Zhi-feng; LI Jun; PENG Hai-dong

    2008-01-01

    Chinese medicine has been used in treating pain for a long time.Much progress has been made in studies on the mechanism of the analgesic effect of Chinese medicine in animal experiments.It is found that the analgesic action may be related to the following actions:(1)Reducing the secretion of peripheral algogenic substances and inducing the secretion of pain-sensitive substances;(2)Alleviating the accumulation of local algogenic substances;(3)Increasing the release of endogenous analgesic substances;(4)Regulating c-fos gene and increasing the secretion of such substances in the central newous system,etc.In this paper,the experimental methods and analgesic effect of Chinese medicines are reviewed.

  1. Progress of Research on Organic Fibrosis with Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    Qing-Lan Wang; Xiao-Ning Wang; Ping Liu

    2016-01-01

    Fibrosis is the remodeling and repair processes of chronic injuries. There are few effective therapies. Chinese medicine formula, the main pattern of traditional Chinese medicine (TCM) in clinic, applies a multi-component, multi-target and complicated approach in the treatment of diseases, and certainly shows good comprehensive therapeutic effects on fibrosis. In this review, the clinical study, effects and mechanism of action of Fuzheng Huayu recipe in the treatment of liver, pulmonary, and renal fibrosis was analyzed and evaluated. Meanwhile, based on the understanding of TCM pathogenesis for liver cirrhosis, this review will also briefly introduce the research of different classical Chinese medicine formulae with various functions in the treatment of experimental liver fibrosis induced by different methods, including comparing the efficacy, analyzing the action characteristics and mechanism of effective formulae, exploring pathological and biological basis of TCM diagnostic and therapeutic pattern, which will contribute to the research of TCM in the treatment of organ fibrosis.

  2. [Study on Chinese Acup-Mox Medicine by YAO Tianmin].

    Science.gov (United States)

    Li, Jianrong; Huang, Longxiang; Du, Guangzhong; Gang, Weijuan

    2015-06-01

    The characteristics and academic thoughts of Chinese Acup-Mox Medicine written by YAO Tianmin during the Republic of China was studied and analyzed in this paper. The academic thoughts of this book were confluence of Chinese and western knowledge, respecting for classics culture but not stubborn, using western science and medicine without worshiping it. The main characteristics were the scientific meridian-acupoint theory, extensive acupoint selection, "qie" method of acupuncture, high recommendation on medicated thread and ironing moxibustion, reinforcing and reducing based on the meridian direction in infantile massage, using acupuncture and cream formula for surgical treatment, and creating his own acupuncture codes.

  3. Tianjin Press of Chinese Herbal Medicines

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    <正>Chinese Traditional and Herbal Drugs The journal started publication monthly since January 1970, is an academic and technical journal sponsored by Chinese Pharmaceutical Association and Tianjin Institute of Pharmaceutical Research. The journal which has a long history over 40 years offers the columns of research papers, brief reports, reviews, dissertation, and special treatises to report the recent achievements of the basic study, production, quality

  4. [Theory of toxic classification of traditional Chinese medicine and recommendations for revision of China pharmacopeia (volume 1)].

    Science.gov (United States)

    Zhao, Junning; Ye, Zuguang

    2012-08-01

    Toxic classification of traditional Chinese medicine, as a contribution of traditional Chinese medicine (TCM) to the recognition of medicinal toxicity and rational use of medicinal materials by Chinese people, is now a great issue related to safe medication, sustainable development and internationalization of Chinese medicine. In this article, the origination and development of toxic classification theory was summarized and analyzed. Because toxic classification is an urgent issue related to TCM industrialization, modernization and internationalization, this article made a systematic analysis on the nature and connotation of toxic classification as well as risk control for TCM industry due to the medicinal toxicity. Based on the toxic studies, this article made some recommendations on toxic classification of Chinese medicinal materials for the revision of China Pharmacopeia (volume 1). From the aspect of scientific research, a new technical guideline for research on toxic classification of Chinese medicine should be formulated based on new biological toxicity test technology such as Microtox and ADME/Tox, because the present classification of acute toxicity of mice/rats can not met the modern development of Chinese medicine any more. The evaluation system and technical SOP of TCM toxic classification should also be established, and they should well balance TCM features, superiority and international requirements. From the aspect of medicine management, list of toxic medicines and their risk classification should be further improved by competent government according to scientific research. In China Pharmacopeia (volume I), such descriptions of strong toxicity, toxicity or mild toxicity should be abandoned when describing medicine nature and flavor. This revision might help promote TCM sustainable development and internationalization, and enhance the competitive capacity of Chinese medicine in both domestic and international market. However, description of strong

  5. UPLC-MS/MS测定中药材中19种氨基甲酸酯农药残留量%Determination of Nineteen Carbamate Pesticides in Chinese Medicinal Materials by UPLC-MS/MS

    Institute of Scientific and Technical Information of China (English)

    张燕; 杨钊; 金红宇; 孙磊; 李欣荣; 吴爱英

    2011-01-01

    OBJECTIVE To establish a method for the determination of 19 carbamate pesticides in Chinese medicinal materials by UPLC triple-quadrupole tandem mass spectrometer.METHODS The samples were determinated by multi-reactions monitoring (MRM) technology.The separation was performed on a Waters ACQUITY UPLC (R) BEH C18 column with acetonitrile -0.1% formic acid ( 1:1 ) with a flow rate of 0.2 mL min-1.Ion mode was set as ESI+.RESULTS The standard curves of the 19 carbamate pesticides showed good linearity over the concentration range of 1.0 - 100 μg · L-1 (r =0.994 7 -0.999 7), respectively.The LODs of 19 carbamate pesticides were in the range of 0.02 - 0.46 μg · L- 1 and the average recoveries were 73.2% - 119.7% at three levels.CONCLUSION The method is rapid, sensitive and suitable for the determination of 19 carbamate pesticides in Chinese medicinal materials.%目的 建立测定中药材中19种氨基甲酸酯农药残留量的超高效液相-串联四级杆质谱方法.方法 多反应监测模式测定,以Waters ACQUITY UPLC(R) BEH C18进行分离,乙腈-0.1%甲酸溶液(1:1),流速:0.2 mL·min-1.离子化模式:ESI+.结果 19种农药测定的线性范围在1.0~100.0 μg·L-1之间,r分别在0.994 7~0.999 7之间,检出质量浓度分别在0.02~0.46μg·L-1之间,3个水平的回收率分别在73.2%~119.7%之间.结论 该方法快速、准确、灵敏,可用于中药材中氨基甲酸酯类农药残留的测定.

  6. The History of Adulterants in Ginseng and the Survey of Ginseng Quality in Current Traditional Chinese Medicinal Material Market%人参混伪品发展历史及当前药材市场人参品质调查

    Institute of Scientific and Technical Information of China (English)

    王晶晶; 陈娜; 韩雪; 陆志成; 王佳雯; 赓迪; 王春梅; 林瑞超

    2016-01-01

    人参混伪品现象从古至今一直存在,古代存在以相似植物假冒人参和浸泡后再销售的情况。为了了解当前人参药材市场现状,对河北省安国市、安徽省亳州市、江西省樟树市3大药材市场进行了市场调研。结果发现,人参伪品已经很少发现,但随着人参价格增长,以次充好问题凸显,主要表现在生晒参和保鲜参经乙醇浸提后加工再售、熏硫防腐、加工红参掺糖、销售病害人参等问题。针对这些问题本文提出增强人参供应能力,建立人参品质评价体系等解决思路,为国家有关部门加强对人参市场监管及质量控制提供参考。%The phenomenon of adulterants in ginseng has been existed since ancient times .that the similar vegetation substituted for ginsengor the soaked ginseng was sold as fresh ginseng .To have a good understanding of current situation of ginseng market ,this paper investigated three traditional Chinese medicinal material market :Anguo market in Hebei province ,Bozhou market in Anhui province and Zhangshu market in Jiangxi province .The investigation of three traditional Chinese medicinal material markets showed that adulterants in ginseng were rarely found , but the problem that shoddy and fake ginseng substituted for the high -quality ones was serious ,especially when the price of ginseng was in-creasing .The dried raw ginseng or fresh ginseng was sold after being soaked in ethanol .Some ginseng was treated with sulfur for anticorrosion . Most of the red ginseng was treated with sugar .We also found the ginseng with disease was sold .To solve these problems ,this paper put forward some suggestions ,for example ,enhancing the ability to supply and setting up quality evaluation system of ginseng .The research might provide ideas for the government to strengthen market supervision and quality control .

  7. [Innovation guidelines and strategies for pharmaceutical engineering of Chinese medicine and their industrial translation].

    Science.gov (United States)

    Cheng, Yi-Yu; Qu, Hai-Bin; Zhang, Bo-Li

    2013-01-01

    This paper briefly analyzes the bottlenecks and major technical requirements for pharmaceutical industry of Chinese medicine, providing current status of pharmaceutical engineering of Chinese medicine. The innovation directions and strategies of the pharmaceutical engineering for manufacturing Chinese medicine are proposed along with the framework of their core technology. As a consequence, the development of the third-generation pharmaceutical technology for Chinese medicine, featured as "precision, digital and intelligent", is recommended. The prospects of the pharmaceutical technology are also forecasted.

  8. [Industry of traditional Chinese patent medicine science and technology development and review].

    Science.gov (United States)

    Lu, Jianwei; Wang, Fang; Yan, Dongmei; Luo, Yun; Yang, Ming

    2012-01-01

    "Fifteen" since, our country Chinese traditional medicine industry science and technology has made remarkable achievements. In this paper, the development of science and technology policy, Chinese medicine industry, platform construction and other aspects were analyzed, showing 10 years of Chinese traditional medicine industry development of science and technology innovation achievement and development, and on the current development of traditional Chinese medicine industry facing the main tasks and guarantee measures are analyzed. PMID:22741452

  9. The biosynthetic products of chinese insect medicine, Aspongopus chinensis

    Science.gov (United States)

    Luo, Xiao-Hong; Wang, Xiao-Zheng; Jiang, Hai-Long; Yang, Jun-Li; Crews, Phillip; Valeriote, Frederick A.; Wu, Quan-Xiang

    2012-01-01

    A new oxazole (1) was obtained from chinese insect medicine Aspongopus chinensis, along with three known N-acetyldopamine derivatives (2–4). Their structures were determined on the basis of NMR and ESI-MS analyses. The possible biosynthetic pathways of the isolated compounds are discussed. Cytotoxicities of those compounds against 10 selected cancer cells were measured in vitro. PMID:22430116

  10. Effects of Traditional Chinese Medicine on Congestive Heart Failure

    Institute of Scientific and Technical Information of China (English)

    任海玲; 李海芸; 江时森

    2002-01-01

    Congestive heart failure (CHF) belongs to the category of "palpitation", "chest pain", "retention of phlegm and fluid" etc. in traditional Chinese medicine (TCM). The medical books of past generations recorded a lot of important prescriptions to treat above-mentioned symptoms. This article briefly summarized certain TCM prescriptions on pharmacological actions and therapeutic effects of CHF.

  11. Strategies for the Development of Chinese Medicine Experience of Hong Kong Special Administrative Region

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@While practitioners of western medicine are the main health care providers in Hong Kong, Chinese medicine plays a significant role in the health care system in Hong Kong. Its popularity of use and its strength in contributing to the health of the community provides the drive for its development. The following summarises the role played by Chinese medicine in the health care system and our strategies in developing Chinese medicine in a western medicine dominant health care system.

  12. [Study of changes in Chinese herbal medicine distribution channel].

    Science.gov (United States)

    Lv, Hua; Yang, Guang; Huang, Lu-Qi

    2014-07-01

    Distribution channel of Chinese herbal medicines has been changing. From Han to Ming Dynasty, Chinese herbal medicine were mainly trafficked to urban by dealers or farmers; From the Ming Dynasty to the foundation of new China, distribution channels are primarily intermediated with township "bazaar" and national distribution center with fixed place and regularly trading hours. In the planned economy period, the state-owned herbal medicine company was the sole medium with monopoly nature. From the mid1980s to the end of last century, planned economy and market economy have been co-existing. Stepping into 21st century, producing area highlighted in the distribution channels. Presence or absence and rise or fall of different types of distribution market went throughout the changing process of distribution channels, which became an important clue. Changes were motivated by economical consideration of channel subject, which originated from commodity characteristic and social environment changes. PMID:25272514

  13. [Changes and establishment of the principle of "Unity of traditional Chinese medicine and western medicine"].

    Science.gov (United States)

    Li, Jian

    2014-11-01

    "Unity of traditional Chinese and western medicine" was one of the three major health work principles at the early founding of the People's Republic of China. It was not only a choice of political strategy in line with the lack of contemporary health-care resources, but also a part of the revolutionary heritage for more than 20 years in the process of the Chinese Communist Party from the preliminary "application of both traditional and western medicine" to the making of the principles of both "cooperation of traditional Chinese and western medicine" and "unity of traditional Chinese and western medicine". All this was closely related to the concrete environment of the Chinese health work of various stages of Yan'an period with strong revolutionary atmosphere and was not the professional demand of the health workers, rather, this principle set up in 1950 was the result of the careful consideration of Mao Zedong and an adjustment guided under the revolutionary framework of Neo-democracy set up under the guidance of the Common Principle which was a bettered adaptation to the contemporary national condition.

  14. Chinese Herbal Medicine in Treatment of Polyhydramnios:a Meta-analysis and Systematic Review

    Institute of Scientific and Technical Information of China (English)

    Fen Zhou; Yu-fang Hao; Yan Chen; Tong Wang

    2013-01-01

    Objective Tocompare the efficacy of Chinese herbal medicine (therapy A) or Chinese herbal medicine plus indomethacin (therapy B) with that of indomethacin alone (therapy C) in treating polyhydramnios.MethodsLiteratures published up toApril 2012 were retrieved from PubMed, Embase and Cochranelibrary, Chinese National Knowledge Infrastructure (CNKI), Chinese Scientific and Technological Periodical Database (VIP), Wangfang, and Traditional Chinese Medicine online.Two researchers collected data independently.The assessment of methodological quality was based on Cochrane handbook and the materials were analyzed with software RevMan 5.1.2. The outcome measure index was relative risk or difference ofmean value (95% confidence interval). The following outcomes were evaluated: (1) general clinical improvement rate; (2) maximum vertical pocket depth; (3) amniotic fluid index (AFI) value; (4) rate of fetalductus arteriosus constriction; (5) incidence of adverse events.ResultsBased on the search strategy, 5 trails involving 1017 patients were finally included. Comparedwith therapy C, therapy A decreased the rate of fetal ductus arteriosus constriction (P<0.01). Therapy B was more effective than therapy C in general clinical improvement and decrease of AFI for polyhydramnios (P<0.01). No serious adverse events were reported in therapy A and therapy B.ConclusionsCompared with therapy C, therapy A and therapy B may appear to be moreeffective for polyhydramnios. However, the exact effectneeds to beconfirmed with well-designedlarge-scale clinical trials.

  15. The use of Chinese herbal drugs in Islamic medicine

    Institute of Scientific and Technical Information of China (English)

    Mojtaba Heyadri; Mohammad Hashem Hashempur; Mohammad Hosein Ayati; Detlev Quintern; Majid Nimrouzi; Seyed Hamdollah Mosavat

    2015-01-01

    This paper investigates some of the ways that Chinese medicine has been transferred to the Western world and to Islamic territories. During the Golden Age of Islam (8th to 13th century CE), the herbal drug trade promoted significant commercial and scientific exchange between China and the Muslim world. Chinese herbal drugs have been described by medieval Muslim medical scholars such as Tabari (870 CE), Rhazes (925 CE), Haly Abbas (982 CE), Avicenna (1037 CE) and Jurjani (1137 CE). The term al-sin (the Arabic word for China) is used 46 times in Avicenna’s Canon of Medicine in reference to herbal drugs imported from China. Cinnamon (dar sini; “Chinese herb”), wild ginger (asaron), rhubarb (rivand-e sini), nutmeg (basbasa), incense tree wood (ood), cubeb (kababe) and sandalwood (sandal) were the most frequently mentioned Chinese herbs in Islamic medical books. There are also multiple similarities between the clinical uses of these herbs in both medical systems. It appears that Chinese herbal drugs were a major component of the exchange of goods and knowledge between China and the Islamic and later to the Western world amid this era.

  16. The use of Chinese herbal drugs in Islamic medicine.

    Science.gov (United States)

    Heyadri, Mojtaba; Hashempur, Mohammad Hashem; Ayati, Mohammad Hosein; Quintern, Detlev; Nimrouzi, Majid; Heyadri, Mojtaba

    2015-11-01

    This paper investigates some of the ways that Chinese medicine has been transferred to the Western world and to Islamic territories. During the Golden Age of Islam (8th to 13th century CE), the herbal drug trade promoted significant commercial and scientific exchange between China and the Muslim world. Chinese herbal drugs have been described by medieval Muslim medical scholars such as Tabari (870 CE), Rhazes (925 CE), Haly Abbas (982 CE), Avicenna (1037 CE) and Jurjani (1137 CE). The term al-sin (the Arabic word for China) is used 46 times in Avicenna's Canon of Medicine in reference to herbal drugs imported from China. Cinnamon (dar sini; "Chinese herb"), wild ginger (asaron), rhubarb (rivand-e sini), nutmeg (basbasa), incense tree wood (ood), cubeb (kababe) and sandalwood (sandal) were the most frequently mentioned Chinese herbs in Islamic medical books. There are also multiple similarities between the clinical uses of these herbs in both medical systems. It appears that Chinese herbal drugs were a major component of the exchange of goods and knowledge between China and the Islamic and later to the Western world amid this era. PMID:26559361

  17. New exploration and understanding of traditional Chinese medicine.

    Science.gov (United States)

    Xutian, Stevenson; Zhang, Jun; Louise, Wozniak

    2009-01-01

    Traditional Chinese Medicine (TCM), originating from oriental philosophy and culture, has been developing through a series of special research and experiments with meditation, accumulation of experiences, and a complete comprehension of ancient theories and methods. However, compared with Conventional Western Medicine (CWM), the theory of TCM is complicated and not easily accepted by Westerners. It is important to explore TCM by using modern scientific techniques and theories. Utilizing his frontier experience and up-to-date scientific knowledge, Dr. Qian Xuesen has been trying to incorporate some key principles with the comprehensive understanding of TCM and clarify difficult but important concepts and principles. Some examples are the existence of invisible matter; 'Qi' and 'Qi monism'; the Heart representing the 'whole will' of human beings; the water environment functioning as a fundamental condition of life; the human body being united with nature and universe as one; the spirit and physical body always being considered unified and connected with the five viscera, especially with the Heart; and the Chinese herbal formula working with different principles than CWM drugs. These works are important for understanding the essence of TCM, the promoting of the modernization of TCM theories by means of the latest of achievements in scientific developments, establishing the direction for future medicines with TCM characteristics, uniting Chinese and Western medicines, and exploiting a bright future for the health of mankind. PMID:19606504

  18. Advances of Chinese and Western Medicine on Rheumatoid Arthritis

    Directory of Open Access Journals (Sweden)

    Na-na HE

    2015-03-01

    Full Text Available Rheumatoid arthritis (RA is a kind of chronic general immunological disease with primary clinical characteristic being joint synovitis, and no specific treatment has been found at present. In China, its morbidity is in an increasing trend, and also shows a trend of getting younger. RA is complicated in symptoms and chronic disease course, leading to joint ankylosis, deformity and even disability, which seriously threaten patients' psychological and physical health as well as the quality of life (QOL. RA, which belongs to “ Bi” symdrome, is termed as “arthroncus of knee” or “severe and migratory arthralgia” in traditional Chinese medicine (TCM, for which TCM focuses on expelling wind to remove cold, tonifying qi to activate blood and dispelling dampness to smooth collaterals while the western medicines mainly based on the principles of anti-inflammation, analgesia and inhibiting autoimmune response. However, both Chinese and western medicines have certain advantages in treating RA. Therefore, this study primarily reviewed the advances of Chinese and western medicines in RA treatment in the hope of providing theoretical basis for the clinical treatment of RA.

  19. Advances of Chinese and Western Medicine on Rheumatoid Arthritis

    Institute of Scientific and Technical Information of China (English)

    HE Na-na; WU Zhi-sen; XING Zhen-long; ZHANG Zhi-gang; SUN Shi-xuan; LIN Fa-cai

    2015-01-01

    Rheumatoid arthritis (RA) is a kind of chronic general immunological disease with primary clinical characteristic being joint synovitis, and no speciifc treatment has been found at present. In China, its morbidity is in an increasing trend, and also shows a trend of getting younger. RA is complicated in symptoms and chronic disease course, leading to joint ankylosis, deformity and even disability, which seriously threaten patients’ psychological and physical health as well as the quality of life (QOL). RA, which belongs to“Bi”symdrome, is termed as“arthroncus of knee”or“severe and migratory arthralgia”in traditional Chinese medicine (TCM), for which TCM focuses on expelling wind to remove cold, tonifying qi to activate blood and dispelling dampness to smooth collaterals while the western medicines mainly based on the principles of anti-inflammation, analgesia and inhibiting autoimmune response. However, both Chinese and western medicines have certain advantages in treating RA. Therefore, this study primarily reviewed the advances of Chinese and western medicines in RA treatment in the hope of providing theoretical basis for the clinical treatment of RA.

  20. The efficacy of Chinese medicine for SARS: a review of Chinese publications after the crisis.

    Science.gov (United States)

    Leung, Ping-Chung

    2007-01-01

    During the SARS crisis in China, 40-60% infected patients, at some stages of their treatment, received Chinese medicine treatment on top of the standard modern medicine treatment. This practice was endorsed and encouraged by the Chinese Center for Disease Control and Prevention, and some details of the herbal treatment were recommended. A review of the publications during and after the SARS crisis enabled us to get an objective view of the true value of the adjuvant therapy using Chinese medicinal herbs. Of the 130 articles searched, 90 were of reasonable quality and contained sufficient information for the enlightenment of the situation. These were reviewed. The results revealed positive but inconclusive indications about the efficacy of the combined treatments using Chinese medicine as an adjuvant. Positive effects using adjuvant herbal therapy included better control of fever, quicker clearance of chest infection, lesser consumption of steroids and other symptoms relief. In a few reports, some evidences of immunological boosterings were also found. More caution is required on the allegation about the efficacy of herbal medicine for the treatment or prevention of viral infection affecting the respiratory tract, while more clinical studies are indicated.

  1. Identification of chemical constituents in traditional Chinese medicine formula using HPLC coupled with linear ion trap-Orbitrap MS from high doses of medicinal materials to equivalent doses of formula: Study on Xiang-Sha-Liu-Jun-Zi-Jia-Jian granules.

    Science.gov (United States)

    Wang, Fengyun; Zhang, Qingqing; Lu, Zhiwei; Wang, Qing; Wang, Meiling; Liu, Yuehong; Fu, Shuang; Gao, Xiaoyan; Tang, Xudong

    2016-05-01

    High-resolution mass spectrometry has been a powerful tool for the research of chemical constituents in traditional Chinese medicine (TCM) formulas. However, the chromatographic peaks were difficult to discriminate clearly in data collection or analysis because of the complexity and the greatly different content of the constituents in TCM formula, which increased the difficulty of identification. In this study, a high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometry based strategy focused on the comprehensive identification of TCM formula constituents was developed. Identification was carried out from a high dose of medicinal materials to equivalent dose of formula. Meanwhile, combined with mass spectrometry data, chromatographic behaviors, reference standards and previous reports, the identification of constituents in Xiang-Sha-Liu-Jun-Zi-Jia-Jian granules was described. 169 compounds were unambiguously or tentatively characterized, mainly including flavonoids, alkaloids, triterpenic acids, triterpene saponins, lactones, sesquiterpenoids and some other compounds. Among them, 11 compounds were unambiguously confirmed by comparing with reference standards. These results demonstrated that the method was effective and reliable for comprehensive identification of constituents of Xiang-Sha-Liu-Jun-Zi-Jia-Jian granules extracts and reveal the material basis of its therapeutic effects. This strategy might propose a research idea for the characterization of multi-constituents in TCM formula. PMID:26935761

  2. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy

    OpenAIRE

    Ming Hong; Ning Wang; Hor Yue Tan; Sai-Wah Tsao; Yibin Feng

    2015-01-01

    In recent decades Chinese medicine has been used worldwide as a complementary and alternative medicine to treat cancer. Plenty of studies have shown that microRNAs (miRNAs) play fundamental roles in many pathological processes, including cancer, while the anti-cancer mechanisms of Chinese medicinal herbs targeting miRNAs also have been extensively explored. Our previous studies and those of others on Chinese medicinal herbs and miRNAs in various cancer models have provided a possibility of ne...

  3. A Brief on Pain and Its Patterns in Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    MOJTABAVI; Seyed; Javad; 郭长青; 陈幼楠

    2009-01-01

    Pain is the most common symptom in clinics.Therefore,the quality,time course and location of pain are important for the diagnosis and treatment.However,pain is very difficult to define,and it is one of the conditions poorly understood by the medical sciences.In Western medicine pain is often described in terms of a penetrating or tissue-destructive process and/or emotional reactions,but in Chinese medicine the pathogenesis and description of pain are different.It is described based on the theories and pa...

  4. To Set Up a Logistic Regression Prediction Model for Hepatotoxicity of Chinese Herbal Medicines Based on Traditional Chinese Medicine Theory.

    Science.gov (United States)

    Liu, Hongjie; Li, Tianhao; Chen, Lingxiu; Zhan, Sha; Pan, Meilan; Ma, Zhiguo; Li, Chenghua; Zhang, Zhe

    2016-01-01

    Aims. To establish a logistic regression (LR) prediction model for hepatotoxicity of Chinese herbal medicines (HMs) based on traditional Chinese medicine (TCM) theory and to provide a statistical basis for predicting hepatotoxicity of HMs. Methods. The correlations of hepatotoxic and nonhepatotoxic Chinese HMs with four properties, five flavors, and channel tropism were analyzed with chi-square test for two-way unordered categorical data. LR prediction model was established and the accuracy of the prediction by this model was evaluated. Results. The hepatotoxic and nonhepatotoxic Chinese HMs were related with four properties (p 0.05). There were totally 12 variables from four properties and five flavors for the LR. Four variables, warm and neutral of the four properties and pungent and salty of five flavors, were selected to establish the LR prediction model, with the cutoff value being 0.204. Conclusions. Warm and neutral of the four properties and pungent and salty of five flavors were the variables to affect the hepatotoxicity. Based on such results, the established LR prediction model had some predictive power for hepatotoxicity of Chinese HMs.

  5. Commentary: "A systems view on the future of medicine: Inspiration from Chinese medicine?"

    NARCIS (Netherlands)

    Verpoorte, R.; Crommelin, D.; Danhof, M.; Gilissen, L.J.W.J.; Schuitmaker, H.; Greef, de J.; Witkamp, R.F.

    2009-01-01

    Chinese medicine could serve as a source of inspiration for drug development. Using systems biology in combination with reverse pharmacology is a novel way for the discovery of novel biological active compounds and targets as well as for proving the occurrence of synergy and prodrugs. A key factor f

  6. Treatment of Chinese Traditional Medicine Wastewater by Photosynthetic Bacteria

    Institute of Scientific and Technical Information of China (English)

    WANG You-zhi; WANG Feng-jun; BAO Li

    2005-01-01

    The influence factors treating wastewater of Chinese traditional medicine extraction by photosynthetic bacteria are tested and discussed. The results indicate that the method of photosynthetic bacteria can eliminate COD and BCD from wastewater in high efficiency. And it also has high load shock resistance. On the conditions of slight aerobic and semi-darkness, treating wastewater of Chinese traditional medicine extraction, the method has better efficiency to eliminate COD and BOD from the wastewater than those by anaerobic illumination and aerobic darkness treatments. After pretreatment of hydrolytic acidization, the removal rate of COD in the wastewater reached more than 85 %, and that rate of BOD reached more than 90% in the treating system of photosynthetic bacteria. It may be more feasible and advantageous than traditional anaerobic biological process to treat organic wastewater using PSB system.

  7. Molecular Imaging in Traditional Chinese Medicine Therapy for Neurological Diseases

    OpenAIRE

    Zefeng Wang; Haitong Wan; Jinhui Li; Hong Zhang(Department of Physics and Center for Quantum Spacetime (CQUeST), Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 121-742 Korea); Mei Tian

    2013-01-01

    With the speeding tendency of aging society, human neurological disorders have posed an ever increasing threat to public health care. Human neurological diseases include ischemic brain injury, Alzheimer's disease, Parkinson's disease, and spinal cord injury, which are induced by impairment or specific degeneration of different types of neurons in central nervous system. Currently, there are no more effective treatments against these diseases. Traditional Chinese medicine (TCM) is focused on, ...

  8. Effects of Traditional Chinese Patent Medicine on Essential Hypertension

    OpenAIRE

    Xiong, Xingjiang; WANG, PENGQIAN; Zhang, Yuqing; Li, Xiaoke

    2015-01-01

    Abstract Traditional Chinese patent medicine (TCPM) is widely used for essential hypertension (EH) in China. However, there is no critically appraised evidence, such as systematic reviews or meta-analyses, regarding the potential benefits and disadvantages of TCPM to justify their clinical use and recommendation. The aim of this review was to systematically evaluate and meta-analyze the effects of TCPM for EH. Seven databases, the Cochrane Library, PubMed, EMBASE, the China National Knowledge...

  9. Chinese Medicinal Leech: Ethnopharmacology, Phytochemistry, and Pharmacological Activities

    Science.gov (United States)

    Dong, Han; Ren, Ji-Xiang; Wang, Jing-Jing; Ding, Li-Shuai; Zhao, Jian-Jun; Liu, Song-Yan; Gao, Hui-Min

    2016-01-01

    Hirudo (Shuizhi in Chinese) is an important Chinese medicine, which possesses many therapeutic properties for the treatment of the cerebral hemorrhage and other thrombosis-related diseases. The phytochemical investigation gave more than 51 compounds including pteridines, phosphatidylcholines, glycosphingolipids, and sterols, as well as some bioactive peptides from the Shuizhi derived from three animal species recorded in the current Chinese Pharmacopoeia. The pharmacological studies on the Shuizhi have revealed various activities such as anticoagulation, antithrombosis, antiatherosclerosis, antiplatelet aggregation, antitumor and anti-inflammatory as well as hemorheology improvement, and protective effects against cerebral ischemia-reperfusion injury. However, some important issues based on the traditional uses of Shuizhi are still not clear. The aim of the present review is to provide comprehensive knowledge on the ethnopharmacology, phytochemistry, and pharmacological activities of Shuizhi. It will provide a potential guidance in exploring main active compounds of Shuizhi and interpreting the action mechanism for the further research. PMID:27274755

  10. Chinese Medicinal Leech: Ethnopharmacology, Phytochemistry, and Pharmacological Activities

    Directory of Open Access Journals (Sweden)

    Han Dong

    2016-01-01

    Full Text Available Hirudo (Shuizhi in Chinese is an important Chinese medicine, which possesses many therapeutic properties for the treatment of the cerebral hemorrhage and other thrombosis-related diseases. The phytochemical investigation gave more than 51 compounds including pteridines, phosphatidylcholines, glycosphingolipids, and sterols, as well as some bioactive peptides from the Shuizhi derived from three animal species recorded in the current Chinese Pharmacopoeia. The pharmacological studies on the Shuizhi have revealed various activities such as anticoagulation, antithrombosis, antiatherosclerosis, antiplatelet aggregation, antitumor and anti-inflammatory as well as hemorheology improvement, and protective effects against cerebral ischemia-reperfusion injury. However, some important issues based on the traditional uses of Shuizhi are still not clear. The aim of the present review is to provide comprehensive knowledge on the ethnopharmacology, phytochemistry, and pharmacological activities of Shuizhi. It will provide a potential guidance in exploring main active compounds of Shuizhi and interpreting the action mechanism for the further research.

  11. 浅论中医与道教%Analysis on Traditional Chinese Medicine and Taoism

    Institute of Scientific and Technical Information of China (English)

    吕宣新; 吕迪阳

    2014-01-01

    道教是中国的本土宗教,中医是中华民族的特色医药学。中医从起源到发展和道教一直密不可分。做一个真正的中医医生,需要了解道教对中医的影响。%Taoism was China's indigenous religion .Traditional Chinese medicine was the Chinese nation's characteristic medicine .From its origins to the development of traditional Chinese medicine and Taoism had been inseparable .Traditional Chinese physician did a real need to understand the impact of Taoism on Chinese medicine .

  12. [Preliminary study on main impacting factors on brand equity of listed traditional Chinese medicine companies].

    Science.gov (United States)

    Tan, Wei; Geng, Dong-Mei; Rong, Xue; Li, Zi; Liu, Wei; Yang, Li; Xu, Si-Qun; Jie, Xiao-Qian

    2013-05-01

    The brand equity is valuable intangible assets of traditional Chinese medicine companies, who are excellent representatives of traditional Chinese medicine enterprises and the most promising ones to good international medicine brands. However, there is still no systematic study on how to correctly evaluate the brand equity of listed traditional Chinese medicine companies at present. To make it clear, the main impacting factors on brand equity of listed traditional Chinese medicine companies, both structured open outline pre-research and closed questionnaire research were adopted for the field survey, and some suggestions for how to protect and enhance the brand equity were also presented on the basis of survey and analysis, in the hope of improving the brand management level of listed traditional Chinese medicine companies, and making a beneficial exploration for the development of brand theory of the traditional Chinese medicine industry. PMID:23944085

  13. Genetic authentication of ginsengand other traditional Chinese medicine

    Institute of Scientific and Technical Information of China (English)

    CCHON; YCCHOW; FYZENG; FCCLEUNG

    2003-01-01

    The main objective of this paper is to review the chemical and genetic methods used in authentication ofginseng, especially the recent advances in microsatellite genotyping and its application to the authentication of othertraditional Chinese medicines (TCM). The standardization and modernization of TCM hinge on the authenticationof their botanical identities. Analysis of well-characterized marker compounds is now the most popular method foridentifying the herbal materials and quality control of TCM, eg, ginsenoside profiling for authentication of Panaxspecies. However, in many herbal species the chemical composition of the plant changes with the external environment and processing conditions, which lowers the reliability of these authentication methods. In the light of theadvances in molecular biotechnology in the past few decades, genetic tools are now considered to provide morestandardized and reliable methods for authentication of herbal materials at the DNA level. These genetic toolsinclude random amplified polymorphic DNA (RAPD), DNA fingerprinting using multi-loci probes, restriction fragment length polymorphism (RFLP), amplified fragment length polymorphism (AFLP), and microsatellite markertechnology. The practicality of these methods varies in terms of their sensitivity, reliability, reproducibility, andrunning cost. Using ginseng as an example, we reviewed the advantages and limitations of these molecular tech-niques in TCM authentication. We have developed a set of microsatellite markers from American ginseng that areable to differentiate Panax ginseng and Panax quinquetolius with the resolution down to farm level, ie, confirmationof its botanical identity and origin. Compared with other molecular techniques, microsatellite marker technology ismore robust, accurate, reproducible, reliable, and sensitive. This is essential for large-scale TCM authenticationcenters.

  14. Exploration and Practice of Research Capacity Cultivation for Students of Chinese Medicinal Materials Major%中药专业大学生科研能力培养的探索与实践

    Institute of Scientific and Technical Information of China (English)

    孟宪生; 包永睿; 郭小瑞; 姚宣; 康廷国

    2011-01-01

    二十一世纪是知识经济与信息的时代,更是科学技术快速发展和全面创新的时代.高校肩负着培养人才、科学研究、服务社会的责任,培养高素质的满足社会需要的合格人才是高等教育肩负的历史使命.当今社会生活的丰富多样性和多元化要求当代大学生要全面发展,更要求高校注重学生德智体美劳和学习态度及能力的全面培养,其中,培养具有科研能力的创新型人才成为中药专业教育的重要任务.%The 21st century is the era of knowledge economy and information, and the era of rapid expansion and over-all creative abilities of science and technology. College bears the responsibility of cultivating talents, researching scientifically and serving the society; its historical mission is to cultivate quality talents who meet the requirements of society. It is needed to be all-round development in colorful and diverse social life of today.College should pay attention to all around development of students' moral, intellectual, physical, aesthetics and labour education and learning attitude and ability. The important task of Chinese medicinal materials major is to cultivate innovative talents with research capacity.

  15. 几种中药材仓贮害虫对丁香的嗅觉行为反应%Olfactory response of storage insect pest of Chinese medicinal materials to clove (Syzygium aromaticum)

    Institute of Scientific and Technical Information of China (English)

    韩群鑫; 黄寿山

    2012-01-01

    The volatile components of clove (Syzygium aromaticum) llower powder were anaiyzea ny combined technique solid phase microextraction (SPME) and gas chromatography and mass spectrome- try (GC-MS), and the olfactory response of several insect pests of stored Chinese medicines materials to the clove flower powder and eugenol were tested by using the four-armed olfactometer. The results showed that major volatile constituents of clove flower powder were eugenol and beta-caryophyllene, and that the eugenol and beta-caryophyllene had repellent effects to Alphitobius diaperinus, but had attraction to Lasio- derma serricorne. Eugenol was the main chemical constituent which had significant taxi to L. serricorne and A. diaperinus. The clove flower powder had repellent effects to Tribolium castaneum.%采用固相微萃取和气相色谱-质谱联用技术对丁香(Syzygium aromaticum)花蕾粉末的化学成分进行了分析,并应用四臂嗅觉仪测试了丁香花蕾粉末及其主要成份丁香酚对几种中药材仓贮害虫的嗅觉行为反应.结果表明,丁香花蕾粉末的主要化学成分为丁香酚和反-石竹烯(反-丁香烯);丁香花蕾粉末和丁香酚对黑菌虫(Alphitobius diaperinus)有驱避作用,而对烟草甲(Lasioderma serricorne)有引诱作用,且丁香酚是丁香中对黑菌虫和烟草甲产生趋性作用的主要化学成分;丁香对赤拟谷盗(Tribolium castaneum)有驱避作用.

  16. Knowledge sharing in Chinese hospitals identifying sharing barriers in traditional Chinese and Western medicine collaboration

    CERN Document Server

    Zhou, Lihong

    2015-01-01

    This book aims to identify, understand and qualify barriers to the patient-centred knowledge sharing (KS) in interprofessional practice of Traditional Chinese Medicine (TCM) and Western Medicine (WM) healthcare professionals in Chinese hospitals.  This collaboration is particularly crucial and unique to China since, contrary to Western practice, these two types of professionals actually work together complimentary in the same hospital. This study adopted a Grounded Theory approach as the overarching methodology to guide the analysis of the data collected in a single case-study design.  A public hospital in central China was selected as the case-study site, at which 49 informants were interviewed by using semi-structured and evolving interview scripts.  The research findings point to five categories of KS barriers: contextual influences, hospital management, philosophical divergence, Chinese healthcare education and interprofessional training.  Further conceptualising the research findings, it is identifie...

  17. [Present situation and development strategies of Chinese medicine preparation in medical institutions].

    Science.gov (United States)

    Wang, Jie; Qiao, Xi-Yao; Lin, Fei

    2015-11-01

    As the actual clinical reflecting of transform Chinese medicine special curative effect, Chinese medicine preparation not only satisfies the need of hospital clinic, scientific research and teaching, but also plays an important role in deepening medical and health system reform, improving people's health level and contributing to the economic growth. However, some problems about administration and approval (tending to western medicine), contraction of the scale, lack of synchronization for clinic and scientific research, and the imbalance of regional development make Chinese medicine preparation move forwards slowly in contradiction. It has not only reduced the effectiveness of the Chinese medicine preparation in hospital clinic, but also brought bad effect on modernized development of Chinese medicine preparation. Research shows that main influencing factors of status quo of Chinese medicine preparation in medical institution include imperfect laws and regulations, high cost than income, and shortage of talents in preparation research. The analysis indicated that the necessary measures to break the contradiction, improve clinical effect of Chinese medicine, and promote the modernization development of Chinese drugs preparation were as follows: government and related departments should strengthen the supporting force in policy by adjusting the examination and approval policy, speeding up dispensing use, reforming pricing system, including into medicare reimbursement, integrating advantage resources and so on; medical institution should actively carry out research and development of traditional Chinese Medicine through drawing the traditional and modern essence, reserving professional talents, and developing characteristic preparation; companies cooperate with hospitals for complementary advantages, which can rapidly transform Chinese medicine preparation into clinical practice.

  18. Tragic result of traditional Chinese medicine manipulation: an unusual case report of bilateral anterior shoulder dislocations

    OpenAIRE

    Chen, Chiu-Liang; Chiu, Shin-Lin; Chu, Chiao-Lee; Lan, Shou-Jen

    2015-01-01

    Background In Taiwan, there is a good universal healthcare system to the patients; however, the majority of Taiwanese seek the complementary and alternative medicine when they are injured or ill. The traditional Chinese medicine, which is a branch of complementary alternative medicine, is prevalent in Taiwan. Without proper sequence of maneuvers, either traditional Chinese medicine or conventional medicine might cause unexpected complications. We report a case of 76-year-old woman who was man...

  19. Model Organisms and Traditional Chinese Medicine Syndrome Models

    Directory of Open Access Journals (Sweden)

    Shuang Ling

    2013-01-01

    Full Text Available Traditional Chinese medicine (TCM is an ancient medical system with a unique cultural background. Nowadays, more and more Western countries due to its therapeutic efficacy are accepting it. However, safety and clear pharmacological action mechanisms of TCM are still uncertain. Due to the potential application of TCM in healthcare, it is necessary to construct a scientific evaluation system with TCM characteristics and benchmark the difference from the standard of Western medicine. Model organisms have played an important role in the understanding of basic biological processes. It is easier to be studied in certain research aspects and to obtain the information of other species. Despite the controversy over suitable syndrome animal model under TCM theoretical guide, it is unquestionable that many model organisms should be used in the studies of TCM modernization, which will bring modern scientific standards into mysterious ancient Chinese medicine. In this review, we aim to summarize the utilization of model organisms in the construction of TCM syndrome model and highlight the relevance of modern medicine with TCM syndrome animal model. It will serve as the foundation for further research of model organisms and for its application in TCM syndrome model.

  20. [Research about re-evaluation of screening of traditonal Chinese medicine symptoms item of post-marketing medicine Xuezhikang].

    Science.gov (United States)

    He, Wei; Xie, Yanming; Wang, Yongyan

    2011-10-01

    The purpose of post-marketing Chinese medicine re-evaluation is to identify Chinese medicine clinical indications, while designing scientific and rational of Chinese medicine symptoms items are important to the result of symptoms re-evaluation. This study give screening of traditional Chinese medicine(TCM) symptoms item of post-marketing medicine Xuezhikang re-evaluation as example that reference to principle dyslipidemia clinical research, academic dissertations, Xuezhikang directions, clinical expert practice experience etc. while standardization those symptom names and screening 41 dyslipidemia common symptoms. Furthermore, this paper discuss about the accoerdance and announcements when screening symptoms item, so as to providing a research thread to manufacture PRO chart for post-marketing medicine re-evaluation. PMID:22292395

  1. [Enlightenment of adverse reaction monitoring on safety evaluation of traditional Chinese medicines].

    Science.gov (United States)

    Song, Hai-bo; Du, Xiao-xi; Ren, Jing-tian; Yang, Le; Guo, Xiao-xin; Pang, Yu

    2015-04-01

    The adverse reaction monitoring is important in warning the risks of traditional Chinese medicines at an early stage, finding potential quality problems and ensuring the safe clinical medication. In the study, efforts were made to investigate the risk signal mining techniques in line with the characteristics of traditional Chinese medicines, particularly the complexity in component, processing, compatibility, preparation and clinical medication, find early risk signals of traditional Chinese medicines and establish a traditional Chinese medicine safety evaluation system based on adverse reaction risk signals, in order to improve the target studies on traditional Chinese medicine safety, effective and timely control risks and solve the existing frequent safety issue in traditional Chinese medicines. PMID:26281610

  2. Computational network pharmacological research of Chinese medicinal plants for chronic kidney disease

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The interaction between drug molecules and target proteins is the basis of pharmacological action.The pharmacodynamic mechanism of Chinese medicinal plants for chronic kidney disease(CKD) was studied by molecular docking and complex network analysis.It was found that the interaction network of components-proteins of Chinese medicinal plants is different from the interaction network of components-proteins of drugs.The action mechanism of Chinese medicinal plants is different from that of drugs.We also found the interaction network of components-proteins of tonifying herbs is different from the interaction network of components-proteins of evil expelling herbs using complex network research approach.It illuminates the ancient classification theory of Chinese medicinal plants.This computational approach could identify the pivotal components of Chinese medicinal plants and their key target proteins rapidly.The results provide data for development of multi-component Chinese medicine.

  3. [Optimization theory and practical application of membrane science technology based on resource of traditional Chinese medicine residue].

    Science.gov (United States)

    Zhu, Hua-Xu; Duan, Jin-Ao; Guo, Li-Wei; Li, Bo; Lu, Jin; Tang, Yu-Ping; Pan, Lin-Mei

    2014-05-01

    Resource of traditional Chinese medicine residue is an inevitable choice to form new industries characterized of modem, environmental protection and intensive in the Chinese medicine industry. Based on the analysis of source and the main chemical composition of the herb residue, and for the advantages of membrane science and technology used in the pharmaceutical industry, especially membrane separation technology used in improvement technical reserves of traditional extraction and separation process in the pharmaceutical industry, it is proposed that membrane science and technology is one of the most important choices in technological design of traditional Chinese medicine resource industrialization. Traditional Chinese medicine residue is a very complex material system in composition and character, and scientific and effective "separation" process is the key areas of technology to re-use it. Integrated process can improve the productivity of the target product, enhance the purity of the product in the separation process, and solve many tasks which conventional separation is difficult to achieve. As integrated separation technology has the advantages of simplified process and reduced consumption, which are in line with the trend of the modern pharmaceutical industry, the membrane separation technology can provide a broad platform for integrated process, and membrane separation technology with its integrated technology have broad application prospects in achieving resource and industrialization process of traditional Chinese medicine residue. We discuss the principles, methods and applications practice of effective component resources in herb residue using membrane separation and integrated technology, describe the extraction, separation, concentration and purification application of membrane technology in traditional Chinese medicine residue, and systematically discourse suitability and feasibility of membrane technology in the process of traditional Chinese

  4. Barriers and countermeasures in developing traditional Chinese medicine in Europe.

    Science.gov (United States)

    Liu, Yunfang; Yang, Zhiping; Cheng, Jing; Fan, Daiming

    2016-09-01

    Traditional Chinese medicine (TCM) is one of the unique cultural treasures of Chinese; it represents a significant feature and prominent advantage of the healthcare cause in China. Data in this paper were fromWorld Health Organization, Chinese Bureau of Statistics, China National Knowledge Infrastructure, and PubMed. In recent years, TCM has established a solid foundation in Europe, which made great strides in legislation, education, research, and international exchange, and has enjoyed a vast development space in the continent. Now, TCM is embracing unprecedented development opportunities in Europe. At the same time, the stiff international competition poses a grave threat to China's TCM industry. With multiple cultural, legal, and institutional challenges, as well as talent shortages in the way, TCM is now facing many difficulties in Europe. To fully prepare and enact active and vigorous steps to seize opportunities, we should have a clear picture about the serious challenges hampering TCM development in Europe. The TCM development at overseas markets has shifted from a spontaneous trade activity into a national strategy spearheaded by the government and participated in by multiple stakeholders. We should make a systematic, comprehensive, and sustainable push in fields such as TCM therapy, healthcare, education, research, culture, and industry development. The ultimate goal is to bring TCMs to the global market and allow them to play a role in safeguarding public health along with modern medicines. PMID:27465827

  5. An overview on adverse drug reactions to traditional Chinese medicines.

    Science.gov (United States)

    Chan, Kelvin; Zhang, Hongwei; Lin, Zhi-Xiu

    2015-10-01

    The safe use of Chinese materia medica (CMM) and products in traditional Chinese medicine (TCM) practice conventionally relies on correct pharmacognostic identification, good agricultural and manufacturing practices based on pharmacopoeia standards and rational/correct CMM combinations with TCM-guided clinical prescribing. These experience-based principles may not absolutely ensure safety without careful toxicological investigations when compared with development of new pharmaceutical drugs. Clinically observed toxicity reports remain as guidance for gathering toxicological evidence, though essential as pharmacovigilance, but are considered as late events for ensuring safety. The overview focuses on the following factors: global development of TCM that has affected conventional healthcare; examples of key toxic substances in CMM; reported adverse drug reactions (ADRs) consequential to taking CMM and TCM products; and proposals on rational approaches to integrate the knowledge of biomedical science and the principles of TCM practice for detecting early ADRs if both TCM products and orthodox drugs are involved. It is envisaged that good control of the quality and standards of CMM and proprietary Chinese medicines can certainly reduce the incidence of ADRs in TCM practice when these medications are used. PMID:25619530

  6. Experimental research of integrative Chinese medicine in multiple sclerosis

    Institute of Scientific and Technical Information of China (English)

    Ke-Ying Zhu; Zheng Kang; Yan Chen; Gen-Cheng Wu; Jun Wang

    2016-01-01

    多发性硬化症是一种严重的神经退行性疾病,会给患者及其家属带来难以估量的痛苦及负担,且目前没有可以根治的办法。因此,有必要从不同的医学体系中寻找能够治疗多发性硬化的治疗方法。中医是最为主要的一类传统与替代医学疗法,且在世界范围内长期被广泛用于治疗包括多发性硬化在内的神经系统疾病。本文主要总结了不同中医疗法在多发性硬化动物模型——实验性变态反应性脑脊髓炎模型中的研究现状,包括中药复方,中药提取物如石杉碱甲、毛萼乙素、姜黄素等,以及针灸。这些研究为多发性硬化证的治疗提供了新的思路,同时也有利于进一步阐明中医中医治疗多发性硬化症的疗效机制。%Multiple sclerosis (MS) is a severe neurodegenerative disease which brings overwhelming sufferings to patients and their families with no radical cure heretofore. Thus, studies of different medicine field and diverse treating methods aiming at the cure for MS should be promoted. Traditional Chinese medicine (TCM) as one of the most important complementary and alternative medicine (CAM), has long been applied to treat MS in China and other nervous system diseases worldwide. Our review aims to summarize the findings of Chinese herbal medicine and acupuncture in the prevention and treatment on animal model of MS, mainly based on experimental autoimmune encephalomyelitis (EAE) model. In this review, experimental research advances of Traditional Chinese medicine in the studies of MS are involved, including Chinese herb decoctions, herb extracts like huperzine A, Eriocalyxin B, Curcumin and also, acupuncture. All of this researches hew out new thoughts towards the treatment of MS and concomitantly, the understanding of the effective mechanism of TCM on MS.

  7. [Evolution, characteristics and enlightenment of self-innovation of traditional Chinese medicine industry].

    Science.gov (United States)

    Feng, Zhi-pei; Tao, Qun-shan; Peng, Dai-yin; Wei, Hua

    2015-06-01

    Traditional Chinese medicine industry is China's strategic emerging industry with great potential for self-innovation. Traditional Chinese medicine industry has successively experienced four stages which are the foundation (laying stage), the core status (establishing stage), the modern system (exploring stage), and the modernization system (constructing stage). Throughout the evolution of the self-innovation in traditional Chinese medicine industry, it presents distinct characteristics which we can explore the beneficial enlightenment. PMID:26552191

  8. A new dawn for the use of traditional Chinese medicine in cancer therapy

    OpenAIRE

    Wei Ming Q; Liu Gang; Parekh Harendra S

    2009-01-01

    Abstract Although traditional Chinese medicine has benefitted one fifth of the world's population in treating a plethora of diseases, its acceptance as a real therapeutic option by the West is only now emerging. In light of a new wave of recognition being given to traditional Chinese medicine by health professionals and regulatory bodies in the West, an understanding of their molecular basis and highlighting potential future applications of a proven group of traditional Chinese medicine in th...

  9. [Process on researching methods of ecology of Chinese traditional medicine resources].

    Science.gov (United States)

    Zhou, Yingqun; Cao, Hailu; Zhao, Runhuai; Chen, Shilin

    2011-02-01

    Though the study on ecology of Chinese traditional medicinal resources methods has achieved great progress in recent years, it is not able to catch the pace of the development of ecology science. Based on the analysis of recent literatures about ecology development trend and Chinese traditional medicinal ecology methods, the progress of Chinese traditional medicinal ecology methods was reviewed, and future study trend was discussed.

  10. Challenges in Research and Development of Traditional Chinese Medicines

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    This review is briefly to recall the history of research and development (R&D) of Chinese materia medica (CMM) and to discuss the challenges of Chinese traditional and herbal medicines (CTHM) facing the modern science and technology. The R&D of CTHM is thought to be an important pathway for new drug discovery. Since1949, about 140 approved new drugs have been developed, among which about 80 originated directly or indirectly from medicinal plants. CTHM has gained interest from the international medical, biomedical, and pharmaceutical institutions as a valuable source of potential medicines. For the modernization of CMM and innovative research of CTHM, there are following challenges to be faced: (1) to evaluate the efficacy, pharmacological properties, action mechanism, and active chemical constituents; (2) to develop new methodologies for the quality and safety of CTHM; (3) to apply new "-omics" techniques to accelerate drug discoveries developed from CTHM; and (4) to apply international practices including good agricultural practice, good manufacturing practice, good laboratory practice, and good clinical practice in the R&D of CTHM.

  11. [Analysis of toxicity of traditional Chinese herbal medicine and its connotation].

    Science.gov (United States)

    Liang, Qi; Xie, Ming

    2009-02-01

    Based on traditional Chinese medicine theory and clinical experience, traditional Chinese herbal drug toxicity has its own special connotation. From the perspective of history and logic, the different comprehension of toxicity between Western medicine and traditional Chinese medicine was discussed after retracing the meaning of "drug toxicity" in traditional Chinese medicine. The authors suggest that it's not feasible to study the Chinese medicine coping mechanically and applying indiscriminately the concept and the research idea about modern drug toxicity since there is different understanding of "drug toxicity" between traditional Chinese medicine and Western medicine. Many control elements are involved in the use of traditional Chinese herbal drugs, and Chinese drug components and actions are complex as compared with Western drugs. More and more drugs with toxicity will be found due to the relativity of drug toxicity. Currently, the study of Chinese drug toxicity should pay more attention to the relation between the toxicity and Chinese drug nature, compatibility and the corresponding disease or syndrome pattern after making definition of Chinese drug toxicity and its connotation. PMID:19216849

  12. [Problems in quality standard research of new traditional Chinese medicine compound].

    Science.gov (United States)

    Zhou, Gang; He, Yan-Ping

    2014-09-01

    The new traditional Chinese medicine compound is the main part of the research of new drug of traditional Chinese medicine (TCM), and the new Chinese herbal compound reflects the characteristics of TCM theory. The new traditional Chinese medicine compound quality standard research is one of the main content of pharmaceutical research, and is also the focus of the new medicine pharmaceutical evaluation content. Although in recent years the research level of new traditional Chinese medicine compound has been greatly improved, but the author during the review found still some common problems existing in new traditional Chinese medicine compound quality standard research data, this paper analyzed the current quality standards for new traditional Chinese medicine compound and the problems existing in the research data, respectively from measurement of the content of index selection, determine the scope of the content, and the quality standard design concept, the paper expounds developers need to concern. The quality of new traditional Chinese medicine compound quality standard is not only itself can be solved, but quality standards is to ensure the key and important content of product quality, improving the quality of products cannot do without quality standards. With the development of science and technology, on the basis of quality by design under the guidance of the concept, new traditional Chinese medicine compound quality standard system will be more scientific, systematic and perfect.

  13. [The technological innovation strategy for quality control of Chinese medicine based on Big Data].

    Science.gov (United States)

    Li, Zhen-hao; Qian, Zhong-zhi; Cheng, Yi-yu

    2015-09-01

    The evolution of the quality control concepts of medical products within the global context and the development of the quality control technology of Chinese medicine are briefly described. Aimed at the bottlenecks in the regulation and quality control of Chinese medicine, using Big Data technology to address the significant challenges in Chinese medicine industry is proposed. For quality standard refinements and internationalization of Chinese medicine, a technological innovation strategy encompassing its methodology, and the R&D direction of the subsequent core technology are also presented. PMID:26978975

  14. Anti-cancer natural products isolated from chinese medicinal herbs

    Directory of Open Access Journals (Sweden)

    Wu Guosheng

    2011-07-01

    Full Text Available Abstract In recent years, a number of natural products isolated from Chinese herbs have been found to inhibit proliferation, induce apoptosis, suppress angiogenesis, retard metastasis and enhance chemotherapy, exhibiting anti-cancer potential both in vitro and in vivo. This article summarizes recent advances in in vitro and in vivo research on the anti-cancer effects and related mechanisms of some promising natural products. These natural products are also reviewed for their therapeutic potentials, including flavonoids (gambogic acid, curcumin, wogonin and silibinin, alkaloids (berberine, terpenes (artemisinin, β-elemene, oridonin, triptolide, and ursolic acid, quinones (shikonin and emodin and saponins (ginsenoside Rg3, which are isolated from Chinese medicinal herbs. In particular, the discovery of the new use of artemisinin derivatives as excellent anti-cancer drugs is also reviewed.

  15. 纳米中药制剂的研究介绍%Introduction of nano chinese medicine

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ Traditional Chinese medicine has been used for thousands of years, and has been contributing to human health. It is considered as a great treasure of mankind. However, nowadays, Traditional Chinese medicine falls behind of modern medicine. It has not been accepted extensively in the worldwide. How can we change this situation? Modernizing traditional Chinese medicine is an effective way. We must improve traditional Chinese medicine with modern science and technology.

  16. Discrimination of Chinese Herbal Medicine by Machine Olfaction

    Directory of Open Access Journals (Sweden)

    Yawen Shao

    2013-02-01

    Full Text Available “Small Sample Size” (SSS problem would occur while using linear discriminant analysis (LDA algorithm with traditional Fisher criterion if the within-class scatter matrix is singular. The combination of maximum scatter difference (MSD criterion and LDA algorithm for solve SSS problem is described. It is employed to detect three kinds of Chinese herbal medicines from different growing areas by machine olfaction. Compared with PCA or PCA + LDA algorithm, the classification result was enhanced. It works out that only a few samples of Anhui Atractylodes are classified incorrectly, however, the classification rate reaches 97.8%.

  17. [Origin and development of umbilical therapy in traditional Chinese medicine].

    Science.gov (United States)

    Zhang, Xue-Wei; Jia, Hong-Ling

    2014-06-01

    The origin and development of umbilical therapy in traditional Chinese medicine is explored from related literature in the history. As a result, the Shang period is regarded as initial period of umbilical therapy, while periods from Han Dynasty, Jin Dynasty and Southern-Northern Dynasties to Sui Dynasty and Tang Dynasty could be taken as stage of primary development. Time from Song Dynasty, Jin Dynasty and Yuan Dynasty to Ming and Qing Dynasties is believed as mature stage. Also the manipulation, application principle, indications and contraindications of umbilical therapy are explained. A brief overview of modern development of umbilical therapy is also described. PMID:25112106

  18. [Summary and analysis of safety warning on clinical application of anti-cold Chinese patent medicine preparations].

    Science.gov (United States)

    Lai, Xiao-xiao; Lin, Hua; Luo, Yi-ni; Wang, Ying-yan; Duan, Xiao-hong; Wang, Lin; Luo, Rui; Chen, Yan-hong

    2015-04-01

    In China, many surveys have shown that most people do not have a correct understanding about cold and administration of anti-cold Chinese patent medicine preparations. The author conducted a systematic summary and analysis on the actual application of anti-cold Chinese patent medicine preparations as well as the warning on safe application of anti-cold Chinese patent medicine preparations in Clinical Medication Information of China Pharmacopoeia, in the expectation of reducing the blind application of anti-cold Chinese patent medicine preparations and providing traditional Chinese medicine pharmacists new ideas in monitoring the safe application of exterior syndrome-relieving Chinese patent medicine preparations. PMID:26281605

  19. Pilot Test of a Culturally Sensitive Hypertension Management Intervention Protocol for Older Chinese Immigrants: Chinese Medicine as Longevity Modality.

    Science.gov (United States)

    Li, Wen-Wen; Gomez, Cynthia A; Tam, Jocelyn Wing-Yin

    2015-11-01

    Hypertension control in older Chinese immigrants remains a significant health issue because of their unique cultural health practices to manage their hypertension. At present, there are limited culturally sensitive health education materials regarding hypertension management tailored for the older Chinese population available for and feasible to use. Because the San Francisco Bay Area has a large population of older Chinese immigrants, development of a culturally appropriate intervention is important to help this population achieve better blood pressure control. The focus of this study was to develop and test the feasibility of a culturally sensitive hypertension management intervention protocol, Chinese Medicine as Longevity Modality. This intervention protocol is implemented as a patient education health program delivered via video format in combination with an individual consultation provided by a nurse in the initial intervention, followed by four phone calls between the initial intervention and the second follow-up visit. The results of the study showed that the proposed intervention protocol was acceptable for the target population. PMID:26571335

  20. Touriam Health Care Center of Xiyuan Hospital China Academy of Traditioal Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Brief Introduction to Xiyuan Hospital Xiyuan Hospital of China Academy of Traditional Chinese Medicine (TCM) was founded in 1955.It is a large comprehensive hospital directly attached to the Chinese Ministry of Health and State Administration of TOM. This hospital governs First Clinical Medical Institute, Gerontology Institute and Clinical Pharmacological Institute of China Academy of TOM, and Clinical Pharmacological Base of the Health Ministry. It is a component of WHO Collaborating Center for Traditional Medicine. It also administers the Agency of Chinese Journal of Integrated Traditional Chinese and Western Medicine, the Society of Clinical Pharmacology of Chinese Drugs of China TOM Association, the Professional Committee of Hematology and Activating Blood-circulation and Removing Blood Stasis of Chinese Society of Integrated Traditional Chinese and Western Medicine.

  1. Use of Chinese medicine by cancer patients: a review of surveys

    Directory of Open Access Journals (Sweden)

    Smith Caroline A

    2011-06-01

    Full Text Available Abstract Chinese medicine has been used to treat a variety of cancer-related conditions. This study aims to examine the prevalence and patterns of Chinese medicine usage by cancer patients. We reviewed articles written in English and found only the Chinese medicine usage from the studies on complementary and alternative medicine (CAM. Seventy four (74 out of 81 articles reported rates of CAM usage ranging from 2.6 to 100%. Acupuncture was reported in 71 out of 81 studies. Other less commonly reported modalities included Qigong (n = 17, Chinese herbal medicine (n = 11, Taichi (n = 10, acupressure (n = 6, moxibustion (n = 2, Chinese dietary therapy (n = 1, Chinese massage (n = 1, cupping (n = 1 and other Chinese medicine modalities (n = 19. This review also found important limitations of the English language articles on CAM usage in cancer patients. Our results show that Chinese medicine, in particular Chinese herbal medicine, is commonly used by cancer patients. Further research is warranted to include studies not written in English.

  2. Drug metabolism and pharmacokinetics of nanodrugs from Chinese medicines and natural products.

    Science.gov (United States)

    Liu, Chang-Xiao; Si, Duan-Yun; Xiao, Xue-Feng; He, Xin; Li, Ya-Zhuo

    2012-06-01

    Over the past few years, nanoscale Chinese medicine has become one of focuses in modern Chinese medicine research. There is an increasing need for a more systematic study on the basic issues involved in traditional Chinese medicine and a more active participation of researchers in the application area of nanoscale traditional Chinese drugs. In this review, author analyzed the current applications of nanotechnology in research and development of drugs from natural products and herbal medicines involving traditional Chinese medicines, and also discussed the bio-medicinal evaluation issues on ADME including bio-distribution and metabolism of nanodrugs. Author noted that great challenges faced in nanodrugs from herb drugs and natural products are the follows: (1) the first challenge is to prepare nanodrug delivery system and quantitatively evaluate the therapeutic effects and safety; (2) the second challenge is to clarify the concrete metabolism course; and (3) the third challenge is to study the pharmacokinetics of nanodrugs. PMID:22475334

  3. Therapeutic Effects of Integrated Traditional Chinese Medicine and Western Medicine in Treating Severe Acute Respiratory Syndrome

    Institute of Scientific and Technical Information of China (English)

    王融冰; 刘军民; 江宇泳; 吴云忠; 王晓静; 池频频; 孙凤霞; 高连印

    2003-01-01

    Objective: To improve the effects of treatment of severe acute respiratory syndrome (SARS) and to explore the clinical significance of integrated traditional Chinese medicine and western medicine (ICWM) in the treatment of SARS and its influence on the chief indexes in the process of the disease. Methods: The clinical study involving observation of 135 patients of SARS was conducted in the randomized, synchronously controlled and open way. The patients were divided into two groups, 68 in the ICWM group and 67 in the control group, all of whom were treated with the same basic treatment of western medicine, but to the ICWM group, Chinese drugs for clearing Heat, detoxifying and removing Dampness were given additionally. The comprehensive effect on relieving fever, cell-mediated immunity, pulmonary inflammation and secondary infection was compared between the two groups. Results: The therapeutic effect in the ICWM group was better than that in the control group in such aspects as steadily lowering body temperature, alleviating general symptoms, accelerating the absorption of pulmonary infiltration and easing cellular immunity suppression. Conclusion: The therapeutic effect of ICWM is better in treating SARS than that of western medicine alone.

  4. Nanotechnology in regenerative medicine: the materials side

    OpenAIRE

    Engel López, Elisabeth; Michiardi, A; Navarro, M.; Lacroix, Damien Jerome; Planell Estany, Josep Anton

    2008-01-01

    Regenerative medicine is an emerging multidisciplinary field that aims to restore, maintain or enhance tissues and hence organ functions. Regeneration of tissues can be achieved by the combination of living cells, which will provide biological functionality, and materials, which act as scaffolds to support cell proliferation. Mammalian cells behave in vivo in response to the biological signals they receive from the surrounding environment, which is structured by nanometre-scaled components. T...

  5. Nanoscale materials for engineering and medicine

    Science.gov (United States)

    Maheshwari, Gunjan; Mallik, Nilanjan; Abot, Jandro; Song, Albert; Head, Emily; Dadhania, Mitul; Shanov, Vesselin; Jayasinghe, Chaminda; Salunke, Pravahan; Lee, Lucy; Hurd, Douglas; Yun, YeoHeung; Yarmolenko, Sergey; Sankar, Jag; Phillips, Paul; Komoroski, Richard A.; Chu, Wen-Jang; Bhattacharya, Amit; Watts, Nelson; Schulz, Mark J.

    2008-03-01

    Materials with nanoscale features have new or improved properties compared to bulk materials. These properties depend on the composition, size, and shape of the material, and include high specific strength and modulus, low melting point, high electrical and thermal conductivity, a large surface area to volume ratio, nearly defect-free structure, magnetic and optical properties, and sensing and actuation properties. This talk will discuss synthesis, processing, and application of nanoscale materials for engineering and medicine. Recent advances in nanoparticle synthesis include development of "Black Cotton" which is centimeter long carbon nanotubes grown in arrays, improved carbon nanofiber material, and development of carbon nanosphere chain material which has the morphology of carbon onions chained together. Applications of these materials under development include spinning Black Cotton into thread to produce a new smart material with reinforcement, sensing, and actuation properties, use of nanotube arrays for electrodes and biosensors, catalyst loaded nanotubes for medical contrast agents, and nanosphere chains for manufacturing composite materials. Overall, this paper shows that "Nanoizing" materials and structures is a hot new technological science that is going to improve many aspects of our lives. These new materials are also generating intellectual property and new opportunities for small companies and universities.

  6. Clinical research of traditional Chinese medicine in big data era.

    Science.gov (United States)

    Zhang, Junhua; Zhang, Boli

    2014-09-01

    With the advent of big data era, our thinking, technology and methodology are being transformed. Data-intensive scientific discovery based on big data, named "The Fourth Paradigm," has become a new paradigm of scientific research. Along with the development and application of the Internet information technology in the field of healthcare, individual health records, clinical data of diagnosis and treatment, and genomic data have been accumulated dramatically, which generates big data in medical field for clinical research and assessment. With the support of big data, the defects and weakness may be overcome in the methodology of the conventional clinical evaluation based on sampling. Our research target shifts from the "causality inference" to "correlativity analysis." This not only facilitates the evaluation of individualized treatment, disease prediction, prevention and prognosis, but also is suitable for the practice of preventive healthcare and symptom pattern differentiation for treatment in terms of traditional Chinese medicine (TCM), and for the post-marketing evaluation of Chinese patent medicines. To conduct clinical studies involved in big data in TCM domain, top level design is needed and should be performed orderly. The fundamental construction and innovation studies should be strengthened in the sections of data platform creation, data analysis technology and big-data professionals fostering and training.

  7. Clinical research of traditional Chinese medicine in big data era.

    Science.gov (United States)

    Zhang, Junhua; Zhang, Boli

    2014-09-01

    With the advent of big data era, our thinking, technology and methodology are being transformed. Data-intensive scientific discovery based on big data, named "The Fourth Paradigm," has become a new paradigm of scientific research. Along with the development and application of the Internet information technology in the field of healthcare, individual health records, clinical data of diagnosis and treatment, and genomic data have been accumulated dramatically, which generates big data in medical field for clinical research and assessment. With the support of big data, the defects and weakness may be overcome in the methodology of the conventional clinical evaluation based on sampling. Our research target shifts from the "causality inference" to "correlativity analysis." This not only facilitates the evaluation of individualized treatment, disease prediction, prevention and prognosis, but also is suitable for the practice of preventive healthcare and symptom pattern differentiation for treatment in terms of traditional Chinese medicine (TCM), and for the post-marketing evaluation of Chinese patent medicines. To conduct clinical studies involved in big data in TCM domain, top level design is needed and should be performed orderly. The fundamental construction and innovation studies should be strengthened in the sections of data platform creation, data analysis technology and big-data professionals fostering and training. PMID:25217972

  8. In vitro anticancer activity of twelve Chinese medicinal herbs.

    Science.gov (United States)

    Shoemaker, Mark; Hamilton, Bobbi; Dairkee, Schanaz H; Cohen, Isaac; Campbell, Michael J

    2005-07-01

    Aqueous extracts of 12 Chinese medicinal herbs, Anemarrhena asphodeloides, Artemisia argyi, Commiphora myrrha, Duchesnea indica, Gleditsia sinensis, Ligustrum lucidum, Rheum palmatum, Rubia cordifolia, Salvia chinensis, Scutellaria barbata, Uncaria rhychophylla and Vaccaria segetalis were evaluated for their antiproliferative activity on eight cancer cell lines as well as on normal human mammary epithelial cells. Five human and three murine cancer cell lines representing different tissues (breast, lung, pancreas and prostate) were used. All the crude aqueous extracts demonstrated growth inhibitory activity on some or all of the cancer cell lines, but only two showed activity against the normal mammary epithelial cells. Overall, the murine cell lines tended to be more sensitive to most of the extracts compared with the human cell lines. Among the human cell lines, cell type specificity was observed for two extracts. These results indicate the potential use of traditional Chinese medicinal herbs as antineoplastic agents and suggest that further studies evaluating their mechanism(s) of action and the isolation of active antitumor compounds are warranted.

  9. Terminology Standardization in Chinese Medicine:The Perspective from UCLA Center for East-West Medicine(Ⅰ)

    Institute of Scientific and Technical Information of China (English)

    Ka-Kit Hui; Sonya Pritzker

    2007-01-01

    @@ INTRODUCTlON by Ka-kit Hui,M.D. Because we recognize the clinical,educational,and cultural importance of translation and terminology in Chinese medicine,we feel that it is imperative to understand the perspectives of all concerned parties.This article thus addresses the issue of terminology standardization in English language Chinese medical Publications from the Point of View of multiple stakeholders in this field at the UCLA Center for East-West Medicine.

  10. Cardiac protection of new compounds from scientific Chinese medicine (SCM)

    Institute of Scientific and Technical Information of China (English)

    ZHU Yi-zhun

    2008-01-01

    Objective Purification and Standardization of Chinese herbal extracts became a hot topic since last decade. Though traditional Chinese medicine (TCM) has been used as a mixture from several herbs for centuries, it has been drawn much attention for studying the standardized Chinese herbs using modern technology. Methods Recently, we compared purified Salvia miltiorrhiza extract (PSME) with angiotensin-converting enzyme inhibitor, Rarnipril, in in vitro experiments and also in vivo using animal model of myocardial infarction. Results PSME was found to have a significantly higher trolox equivalent antioxidant capacity which indicated a great capacity for scavenging free radicals. PSME could also prevent pyrogalto red bleaching and DNA damage. After 2 weeks treatment with PSME or Ramipril, survival rates of rats with experimental myocardial infarction were marginally increased (68.2% and 71.4%) compared with saline (61.5%). In another recent study, we evaluated the cardioprotective effects of PSME on myocardial ischemia/reperfusion injury in isolated rat hearts and in hypoxic vascular smooth muscle calls. We found that PSME treated hearts showed significant postischemic contractile function recovery (develop pressure recovered to 44.2±4.9 % versus 17.1±5.7 %, P<0.05; maximum contraction recovered to 57.2±5.9 % versus 15.1±6.3%, P<0. 001; maximum relaxation restored to 69.3±7.3% versus 15.4±6.3%, P<0.001 in PSME and control group respectively). Conclusions Significant elevated in end-diastolic pressure, which indicated LV stiffening in PSME hearts might be resulted by exceed dose of PSME used. Purified and standardized Chinese herb could provide an alternative regimen for the prevention of ischemic heart disease.

  11. Determining method and conditional factors of electrochemical fingerprint of Chinese traditional medicine

    Institute of Scientific and Technical Information of China (English)

    ZHANG TaiMing; LIANG YiZeng; YUAN Bin; DING Feng; ZHANG YaPeng; WEI ManQiong; CHEN Xu

    2007-01-01

    The thermodynamic systems and kinetic model suitable for the electrochemical token of the component throng in Chinese traditional medicines have been analyzed.It has been indicated that the damp oscillatory reactions in the non-equilibrium close system and open system without the supplement of dissipative substance have important significance for the throng token and analysis of chemical components in Chinese traditional medicines.Various factors influencing the electrochemical fingerprint, such as reactant species and their concentrations, electrode types, temperature, stir rate, the kind, dosage and granularity of Chinese traditional medicines, have amply been researched by the B-Z oscillatory reaction which used malonic acid as a main dissipative substance.In addition, the quantitative information about the chemical components in Chinese traditional medicines has been discussed in detail.The method and its conditions for determining the electrochemical fingerprint used in scientifically distinguishing and evaluating Chinese traditional medicines have successfully been put forward.

  12. [Construction and implementation of quality control index for clinical safety of Chinese medicine injection].

    Science.gov (United States)

    Jiang, Jun-jie; Xie, Yan-ming

    2015-12-01

    In order to ensure the authenticity and accuracy of traditional Chinese medicine injection safety monitoring data, Chinese medicine injection safety monitoring quality control indicators, including the monitoring center, monitoring personnel, hardware conditions, monitoring progress and the number of patients into the group, original documents and archives management, electronic data, adverse events, quality management were constructed. Its application in the creation of major new drugs technology major projects, 10 kinds of traditional Chinese medicine injections clinical safety monitoring quality control work, found the missing case surveillance, not reported adverse events, only reported adverse reactions, electronic data reporting lag, lack of level of efforts to control the problem, and corrected, the traditional Chinese medicine injection safety monitoring of quality control and quality assurance, and subsequent Chinese medicine safety monitoring quality control to provide the reference. PMID:27245020

  13. Rare Disease Drug Policy and Inheritance and Innovation of Traditional Chinese Medicine

    OpenAIRE

    Baxian Yi; Guangping Wang; Xiaoming Wu

    2014-01-01

    Traditional Chinese medicine is an important component of the health care system in Chinese medical treatment and public health. Rare disease drugs in difficult miscellaneous diseases in traditional Chinese medicine have similar characteristics with the rare disease drugs (orphan drugs) in European and American countries, which both are characterized by individualized medical treatment. The two are different in the development thought. Treatment of difficult miscellaneous diseases in the trad...

  14. Comments on Nigel Wiseman's A Practical Dictionary of Chinese Medicine ( Ⅱ )-- On the Use of Western Medical Terms to Express the Concepts of Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Mr. Wiseman believes that Western medical terms chosen as equivalents of Chinese medical terms should be the words known to all speakers and not requiring any specialist knowledge or instrumentation to understand or identify, and strictly technical Western medical terms should be avoided regardless of their conceptual conformity to the Chinese terms. Accordingly, many inappropriate Western medical terms are selected as English equivalents by the authors of the Dictionary, and on the other hand, many ready-made appropriate Western medical terms are replaced by loan English terms with the Chinese style of word formation.The experience gained in solving the problems of translating Western medical terms into Chinese when Western medicine was first introduced to China is helpful for translating Chinese medical terms into English. How-ever, the authors of the Dictionary adhere to their own opinions, ignoring others experience. The English terms thus created do not reflect the genuine meaning of the Chinese terms, but make the English glossary in chaos. The so-called true face of traditional Chinese revealed by such terms is merely the Chinese custom of word formation and metaphoric rhetoric. In other words, traditional Chinese medicine is not regarded as a system of medicine but merely some Oriental folklore.

  15. [Present situation and development strategies of Chinese medicine preparation in medical institutions].

    Science.gov (United States)

    Wang, Jie; Qiao, Xi-Yao; Lin, Fei

    2015-11-01

    As the actual clinical reflecting of transform Chinese medicine special curative effect, Chinese medicine preparation not only satisfies the need of hospital clinic, scientific research and teaching, but also plays an important role in deepening medical and health system reform, improving people's health level and contributing to the economic growth. However, some problems about administration and approval (tending to western medicine), contraction of the scale, lack of synchronization for clinic and scientific research, and the imbalance of regional development make Chinese medicine preparation move forwards slowly in contradiction. It has not only reduced the effectiveness of the Chinese medicine preparation in hospital clinic, but also brought bad effect on modernized development of Chinese medicine preparation. Research shows that main influencing factors of status quo of Chinese medicine preparation in medical institution include imperfect laws and regulations, high cost than income, and shortage of talents in preparation research. The analysis indicated that the necessary measures to break the contradiction, improve clinical effect of Chinese medicine, and promote the modernization development of Chinese drugs preparation were as follows: government and related departments should strengthen the supporting force in policy by adjusting the examination and approval policy, speeding up dispensing use, reforming pricing system, including into medicare reimbursement, integrating advantage resources and so on; medical institution should actively carry out research and development of traditional Chinese Medicine through drawing the traditional and modern essence, reserving professional talents, and developing characteristic preparation; companies cooperate with hospitals for complementary advantages, which can rapidly transform Chinese medicine preparation into clinical practice. PMID:27071242

  16. [Analysis on prescription rules of treating senile dementia based on traditional Chinese medicine inheritance auxiliary systems].

    Science.gov (United States)

    Zong, Xin; Ji, Xu-Ming; Wei, Feng-Qin; Shi, Zuo-Rong

    2014-02-01

    This is designed to analyze and summarize medication rules for treating senile dementia with Chinese medicine in CNKI according to the traditional Chinese medicine (TCM) inheritance auxiliary system. Collect documents in CNKI that account treating senile dementia with Chinese formula; filter and establish a formula database, and then to search for medication rules on the TCM inheritance auxiliary system. It is filtered that 104 formulas are used for treating senile dementia screening treat senile dementia, involving 147 kinds of Chinese medicine. Tonic medicine are most frequently used, followed by the medicine of activating blood circulation and resuscitating; medicine pair most used is Ligusticum chuanxiong Hort-Acorus tatarinowii, accounting for 27.9% of all formula. And then 8 core pairs and 4 new formulas are evolved. Analysis on formulas for treating senile dementia filtered form CNKI by TCM inheritance auxiliary system shows prescription is mainly tonifying, activating blood circulation and resuscitating, that reveals prescription rules, to provide a reference for clinical treatment.

  17. Progresses in Applications of Stable Isotope Technology to Determining Geographical Origins of Traditional Chinese Medicines

    Directory of Open Access Journals (Sweden)

    WANG Li-ming

    2015-11-01

    Full Text Available Identification of proper geographical origin of traditional Chinese medicine is critical for guaranteeing the quality and efficacy of the medicine, safeguarding the market order, and reducing the medical negligence rate due to fake products. Stable isotope technology, as one of the most efficient methods to determine agricultural products authenticity and traceability, have great advantages and theoretical basis for determining geo-origin of traditional Chinese medicine, and it has been applied to many expensive herbs. In this review, the basic principles of isotopic traceability were firstly introduced. We then elaborate in details the frequently-used isotopic indicators in the geo origin studies of traditional Chinese medicine. We also provide a summary of current research progresses and point out some directions for future research. The purpose of this paper is to promote the applications of stable isotopes to traditional Chinese medicine traceability studies and the establishment of the isotopic database and the improvement of the medicine traceability.

  18. Using the Theory of Planned Behaviour to Explain Use of Traditional Chinese Medicine among Hong Kong Chinese in Britain

    OpenAIRE

    Tina L. Rochelle; Shardlow, Steven M.; Sik Hung Ng

    2015-01-01

    The UK Chinese are known for their underutilisation of western healthcare services. Reasons for this underutilisation are complex. The Theory of Planned Behaviour (TPB) is a widely used model of social cognition, which in the present study is being applied to traditional Chinese medicine (TCM) utilisation and satisfaction with TCM services. Two hundred and seventy-two UK Chinese aged between 15 and 91 years (M = 46.55; SD = 18.53) enrolled in the study. TCM utilisation was associated with gen...

  19. Research progress of traditional Chinese medicine treatment of diabeticnephropathy

    Institute of Scientific and Technical Information of China (English)

    Xiaoming Wu; Na Zhang; Yanbin Gao

    2014-01-01

    Diabetic nephropathy is the main reason of the end-stage renal failure and endanger human health seriously.Ef-fective treatment of diabetic nephropathy is in an urgent demand.In recent years,we confirmed the good effect of TCM on dia-betic nephropathy by evidence based medicine method.We also explored the treatment mechanism of TCM on diabetic ne-phropathy from overall level,cellular level and molecular level and found that both single herb and Chinese herbal compound can treat diabetic nephropathy by multiple targets control.TCM may become one of the effective methods for treating diabetic ne-phropathy.This paper will review the advances in this research field of recent years and provide references for future researches.

  20. Medicinal protection with Chinese herb-compound against radiation damage

    International Nuclear Information System (INIS)

    Experiments were carried out on mice and the subjects irradiated for cancer therapy to evaluate the protective efficacy of a Chinese medicinal herb-compound (CMHC). The lethality and the degree of leucopenia caused by radiation in mice medicated with CMHC were significantly less in comparison with control mice (p less than 0.01 and p less than 0.001, respectively). CMHC significantly improved the WBC and the thrombocytes in irradiated workers (p less than 0.01 and p less than 0.001, respectively). The WBC count of 40 patients under radiotherapy while treated with CMHC recovered from 3450 +/- 77/c.mm to 5425 +/- 264/c.mm (p less than 0.001); whereas, in the control group, without any medication, the WBC count dropped significantly (p less than 0.001). Our results revealed the applicabilities of CMHC in protection against radiation damage in spaceflight and in other fields

  1. Medicinal protection with Chinese herb-compound against radiation damage

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, R.J.; Qian, J.K.; Yang, G.H.; Wang, B.Z.; Wen, X.L. (Institute of Space Medico-Engineering, Beijing (China))

    1990-08-01

    Experiments were carried out on mice and the subjects irradiated for cancer therapy to evaluate the protective efficacy of a Chinese medicinal herb-compound (CMHC). The lethality and the degree of leucopenia caused by radiation in mice medicated with CMHC were significantly less in comparison with control mice (p less than 0.01 and p less than 0.001, respectively). CMHC significantly improved the WBC and the thrombocytes in irradiated workers (p less than 0.01 and p less than 0.001, respectively). The WBC count of 40 patients under radiotherapy while treated with CMHC recovered from 3450 +/- 77/c.mm to 5425 +/- 264/c.mm (p less than 0.001); whereas, in the control group, without any medication, the WBC count dropped significantly (p less than 0.001). Our results revealed the applicabilities of CMHC in protection against radiation damage in spaceflight and in other fields.

  2. Novel PDE4 inhibitors derived from Chinese medicine forsythia.

    Directory of Open Access Journals (Sweden)

    Tiffany A Coon

    Full Text Available Cyclic adenosine monophosphate (cAMP is a crucial intracellular second messenger molecule that converts extracellular molecules to intracellular signal transduction pathways generating cell- and stimulus-specific effects. Importantly, specific phosphodiesterase (PDE subtypes control the amplitude and duration of cAMP-induced physiological processes and are therefore a prominent pharmacological target currently used in a variety of fields. Here we tested the extracts from traditional Chinese medicine, Forsythia suspense seeds, which have been used for more than 2000 years to relieve respiratory symptoms. Using structural-functional analysis we found its major lignin, Forsynthin, acted as an immunosuppressant by inhibiting PDE4 in inflammatory and immune cell. Moreover, several novel, selective small molecule derivatives of Forsythin were tested in vitro and in murine models of viral and bacterial pneumonia, sepsis and cytokine-driven systemic inflammation. Thus, pharmacological targeting of PDE4 may be a promising strategy for immune-related disorders characterized by amplified host inflammatory response.

  3. Novel PDE4 Inhibitors Derived from Chinese Medicine Forsythia

    Science.gov (United States)

    Coon, Tiffany A.; McKelvey, Alison C.; Weathington, Nate M.; Birru, Rahel L.; Lear, Travis; Leikauf, George D.; Chen, Bill B.

    2014-01-01

    Cyclic adenosine monophosphate (cAMP) is a crucial intracellular second messenger molecule that converts extracellular molecules to intracellular signal transduction pathways generating cell- and stimulus-specific effects. Importantly, specific phosphodiesterase (PDE) subtypes control the amplitude and duration of cAMP-induced physiological processes and are therefore a prominent pharmacological target currently used in a variety of fields. Here we tested the extracts from traditional Chinese medicine, Forsythia suspense seeds, which have been used for more than 2000 years to relieve respiratory symptoms. Using structural-functional analysis we found its major lignin, Forsynthin, acted as an immunosuppressant by inhibiting PDE4 in inflammatory and immune cell. Moreover, several novel, selective small molecule derivatives of Forsythin were tested in vitro and in murine models of viral and bacterial pneumonia, sepsis and cytokine-driven systemic inflammation. Thus, pharmacological targeting of PDE4 may be a promising strategy for immune-related disorders characterized by amplified host inflammatory response. PMID:25549252

  4. Prevention and Treatment of Osteoporosis with Chinese Herbal Medicines

    Institute of Scientific and Technical Information of China (English)

    ZHAO Xiao-ling; FENG Yu-xiong; PENG Yong

    2012-01-01

    In this paper,laboratory reports,medication rules,formulating principles,and research methods are summarized and analyzed,including single herb,compound herbs,and the problems in the prevention and treatment of osteoporosis(OP)within the past decade.With widely recognized efficacy,satisfying achievements have been achieved in preventing and treating OP with Chinese herbal medicines(CHM).However,due to the complex constituents,the pharmacological activities and mechanism of CHM are not clear yet,and there is no unified standard on the diagnosis and syndrome differentiation of OP and the efficacy evaluation of CHM in the treatment.Accordingly,the research in the future should focus on the pharmacology and standardization of CHM in treating OP.

  5. Research advances in traditional Chinese medicine syndromes in cancer patients.

    Science.gov (United States)

    Ji, Qing; Luo, Yun-quan; Wang, Wen-hai; Liu, Xuan; Li, Qi; Su, Shi-bing

    2016-01-01

    Traditional Chinese medicine (TCM) syndrome, also known as TCM ZHENG or TCM pattern, is an integral and essential part of TCM theory that helps to guide the design of individualized treatments. A TCM syndrome, in essence, is a characteristic profile of all clinical manifestations in one patient that can be readily identified by a TCM practitioner. In this article, the authors reviewed the presentations of TCM syndromes in seven common malignancies (liver, lung, gastric, breast, colorectal, pancreatic and esophageal cancers), the objectivity and the standardization of TCM syndrome differentiation, the evaluation of TCM syndrome modeling in cancer research, and syndrome differentiation-guided TCM treatment of cancers. A better understanding of TCM syndrome theory, as well as its potential biological basis, may contribute greatly to the clinical TCM diagnosis and the treatment of cancer.

  6. Functional Somatic Syndromes: Emerging Biomedical Models and Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Steven Tan

    2004-01-01

    Full Text Available The so-called functional somatic syndromes comprise a group of disorders that are primarily symptom-based, multisystemic in presentation and probably involve alterations in mind-brain-body interactions. The emerging neurobiological models of allostasis/allostatic load and of the emotional motor system show striking similarities with concepts used by Traditional Chinese Medicine (TCM to understand the functional somatic disorders and their underlying pathogenesis. These models incorporate a macroscopic perspective, accounting for the toll of acute and chronic traumas, physical and emotional stressors and the complex interactions between the mind, brain and body. The convergence of these biomedical models with the ancient paradigm of TCM may provide a new insight into scientifically verifiable diagnostic and therapeutic approaches for these common disorders.

  7. Systems biology-based diagnostic principles as pillars of the bridge between Chinese and Western medicine

    NARCIS (Netherlands)

    Greef, J. van der; Wietmarschen, H. van; Schroën, J.; Wang, M.; Hankemeier, T.; Xu, G.

    2010-01-01

    Innovative systems approaches to develop medicine and health care are emerging from the integration of Chinese and Western medicine strategies, philosophies and practices. The two medical systems are highly complementary as the reductionist aspects of Western medicine are favourable in acute disease

  8. Chinese herbal medicine and acupuncture for the treatment of cardiovascular disease

    Institute of Scientific and Technical Information of China (English)

    Jun Xu; Haiyun Wu

    2009-01-01

    @@ Traditional Chinese medicine (TCM) is one of the world's oldest healing systems. TCM includes herbal medicine, acupuncture, moxibustion, massage, food therapy, and physical exercise, such as shadow boxing. In modern China, TCM is a fully institutionalised part of health care and widely used with Western medicine.

  9. Traditional Chinese medicine Yisui Tongjing relieved neural severity in experimental autoimmune neuritis rat model

    Science.gov (United States)

    Zhang, Erli; Li, Mingquan; Zhao, Jianjun; Dong, Yuxiang; Yang, Xueqin; Huang, Jingbo

    2016-01-01

    Objective To study the effect of Yisui Tongjing (YSTJ) prescription on motor nerve conduction velocity (MNCV) and microstructure of the sciatic nerve in experimental autoimmune neuritis (EAN) rats, the Guillain–Barré syndrome classic animal models. Materials and methods In this study, we established an EAN model in Lewis rats by immunization. We evaluated the potential clinical application of a traditional Chinese medicine YSTJ by intragastric administration and compared its effect with immunoglobulin. The sciatic MNCV was measured by electrophysiology experiment. Hematoxylin–eosin staining and transmission electron microscope analysis were used to determine the pathologically morphological changes before and after YSTJ application. Results We found that application of YSTJ could significantly alleviate the clinical signs in EAN rats. The treatment also increased MNCV in the sciatic nerve compared to that in the untreated nerve. Demyelination in the sciatic nerve in EAN rats was significantly ameliorated, and newly generated myelinated nerve fibers were observed with treatment of high dose of YSTJ. Conclusion This study showed that the traditional Chinese medicine YSTJ was likely to serve as a therapeutic medicine in autoimmune neuropathies, providing an effective and economic means to the treatment of Guillain–Barré syndrome. PMID:27729792

  10. 中药名与中医药文化%Traditional Chinese Medicine Name and Chinese Medical Culture

    Institute of Scientific and Technical Information of China (English)

    何明举

    2014-01-01

    Traditional Chinese medicine name is the carrier of culture of Chinese medicine,the crystallization of marriage of Chinese medicine and cultural art,which contains rich thoughts of humanities and philosophy. Since ancient times,it has spread more,and is a unique cultural landscape in the history of Chinese,it is precious wealth conceived of the development of Chinese medicine business by people,which has shown the cultural characteristics of traditional Chinese medicine incisively and vividly.%中药名是中医药文化的载体,是中医药与文化艺术联姻的结晶,蕴含着丰富的人文科学和哲学思想。自古多有流传,可谓华夏史上一道奇特的文化景观,是人民在千百年的中医药事业奋斗发展中孕育出来的宝贵财富,把中医学的文化特色彰显得淋漓尽致。

  11. [Sample size calculation in clinical post-marketing evaluation of traditional Chinese medicine].

    Science.gov (United States)

    Fu, Yingkun; Xie, Yanming

    2011-10-01

    In recent years, as the Chinese government and people pay more attention on the post-marketing research of Chinese Medicine, part of traditional Chinese medicine breed has or is about to begin after the listing of post-marketing evaluation study. In the post-marketing evaluation design, sample size calculation plays a decisive role. It not only ensures the accuracy and reliability of post-marketing evaluation. but also assures that the intended trials will have a desired power for correctly detecting a clinically meaningful difference of different medicine under study if such a difference truly exists. Up to now, there is no systemic method of sample size calculation in view of the traditional Chinese medicine. In this paper, according to the basic method of sample size calculation and the characteristic of the traditional Chinese medicine clinical evaluation, the sample size calculation methods of the Chinese medicine efficacy and safety are discussed respectively. We hope the paper would be beneficial to medical researchers, and pharmaceutical scientists who are engaged in the areas of Chinese medicine research. PMID:22292397

  12. Safety concerns of herbal products and traditional Chinese herbal medicines: dehydropyrrolizidine alkaloids and aristolochic acid.

    Science.gov (United States)

    Stegelmeier, Bryan L; Brown, Ammon W; Welch, Kevin D

    2015-12-01

    In many countries, including the United States, herbal supplements, tisanes and vegetable products, including traditional Chinese medicines, are largely unregulated and their content is not registered, monitored or verified. Consequently, potent plant toxins including dehydropyrrolizidine alkaloids and other potential carcinogens can contaminate these products. As herbal and food supplement producers are left to their own means to determine the safety and purity of their products prior to marketing, disturbingly often good marketing practices currently in place are ignored and content is largely undocumented. Historical examples of poisoning and health issues relating to plant material containing dehydopyrrolizidine alkaloids and aristolochic acids were used as examples to demonstrate the risk and potential toxicity of herbal products, food supplements, or traditional medicines. More work is needed to educate consumers of the potential risk and require the industry to be more responsible to verify the content and insure the safety of their products. PMID:26152912

  13. Anti-fibro-hepatocarcinogenic Chinese herbal medicines: A mechanistic overview.

    Science.gov (United States)

    Boye, Alex; Yang, Yan; Asenso, James; Wei, Wei

    2016-01-01

    Chinese herbal medicine (CHM) is an integral component of complementary/alternative medicine and it is increasingly becoming the preferred therapeutic modality for the treatment of liver fibrosis and hepatocellular carcinoma (HCC) worldwide. Accordingly, the World Health Organization (WHO) has attested to the popularity and efficacy of indigenous herbal therapies including CHM as a first line of treatment for some diseases including liver disorders. However, the WHO and drug discovery experts have always recommended that use of indigenous herbal remedies must go hand-in-hand with the requisite mechanistic elucidation so as to constitute a system of verification of efficacy within the ethnobotanical context of use. Although many CHM experts have advanced knowledge on CHM, nonetheless, more enlightenment is needed, particularly mechanisms of action of CHMs on fibro-hepato-carcinogenesis. We, herein, provide in-depth mechanisms of the action of CHMs which have demonstrated anti-fibro-hepatocarcinogenic effects, in pre-clinical and clinical studies as published in PubMed and other major scientific databases. Specifically, the review brings out the important signaling pathways, and their downstream targets which are modulated at multi-level by various anti-fibro-hepatocarcinogenic CHMs. PMID:27366355

  14. Publishing Chinese medicine knowledge as Linked Data on the Web

    Directory of Open Access Journals (Sweden)

    Zhao Jun

    2010-07-01

    Full Text Available Abstract Background Chinese medicine (CM draws growing attention from Western healthcare practitioners and patients. However, the integration of CM knowledge and Western medicine (WM has been hindered by a barrier of languages and cultures as well as a lack of scientific evidence for CM's efficacy and safety. In addition, most of CM knowledge published with relational database technology makes the integration of databases even more challenging. Methods Linked Data approach was used in publishing CM knowledge. This approach was applied to publishing a CM linked dataset, namely RDF-TCM http://www.open-biomed.org.uk/rdf-tcm/ based on TCMGeneDIT, which provided association information about CM in English. Results The Linked Data approach made CM knowledge accessible through standards-compliant interfaces to facilitate the bridging of CM and WM. The open and programmatically-accessible RDF-TCM facilitated the creation of new data mash-up and novel federated query applications. Conclusion Publishing CM knowledge in Linked Data provides a point of departure for integration of CM databases.

  15. Anti-fibro-hepatocarcinogenic Chinese herbal medicines: A mechanistic overview

    Science.gov (United States)

    Boye, Alex; Yang, Yan; Asenso, James; Wei, Wei

    2016-01-01

    Chinese herbal medicine (CHM) is an integral component of complementary/alternative medicine and it is increasingly becoming the preferred therapeutic modality for the treatment of liver fibrosis and hepatocellular carcinoma (HCC) worldwide. Accordingly, the World Health Organization (WHO) has attested to the popularity and efficacy of indigenous herbal therapies including CHM as a first line of treatment for some diseases including liver disorders. However, the WHO and drug discovery experts have always recommended that use of indigenous herbal remedies must go hand-in-hand with the requisite mechanistic elucidation so as to constitute a system of verification of efficacy within the ethnobotanical context of use. Although many CHM experts have advanced knowledge on CHM, nonetheless, more enlightenment is needed, particularly mechanisms of action of CHMs on fibro-hepato-carcinogenesis. We, herein, provide in-depth mechanisms of the action of CHMs which have demonstrated anti-fibro-hepatocarcinogenic effects, in pre-clinical and clinical studies as published in PubMed and other major scientific databases. Specifically, the review brings out the important signaling pathways, and their downstream targets which are modulated at multi-level by various anti-fibro-hepatocarcinogenic CHMs. PMID:27366355

  16. Management of SAH with traditional Chinese medicine in China.

    Science.gov (United States)

    Wang, Chunxue; Zhao, Xingquan; Mao, Shujing; Wang, Yongjun; Cui, Xiangning; Pu, Yuehua

    2006-06-01

    China lacks large scale authorized epidemiological study results in allusion to subarachnoid hemorrhage (SAH) within recent 15 years since MONICA (multinational monitoring of trends and determinants in cardiovascular disease) study revealed SAH situation in China in 2000. The main cause of SAH in China is aneurysm which takes up 30-50%, while over 90% aneurysm locates at Willis circle. Early surgery for SAH after aneurysm rupture is the dominant procedure to deal with SAH in China. Moreover, calcium antagonists rank the absolute leading position for cerebral vascular spasm (CVS) among medication-based treatment options. However, traditional Chinese medicine such as Salvia miltiorrhiza, Acanthopanax senticosus, Ginkgo biloba, Pueraria lobata, Liguisticum chuanxiong, cow bezoar, Diospyros kaki and Gynostemma pentaphyllum have been proven beneficial in CVS prevention and treatment, while Salvia miltiorrhiza and TCM soup have unique effects on bleeding absorption. In addition, aescine and some TCM soup might relieve strong headache after SAH. In general, TCM integrated with western medicine have shown unique advantages in the current treatment of SAH in China. However, it is a pity that China still lacks larger scale randomized controlled trials and research on SAH treatment focusing on TCM and the related mechanism of TCM on SAH still need to be investigated further.

  17. Anticancer effects of Chinese herbal medicine, science or myth?

    Institute of Scientific and Technical Information of China (English)

    RUAN Wen-jing; LAI Mao-de; ZHOU Jian-guang

    2006-01-01

    Currently there is considerable interest among oncologists to find anticancer drugs in Chinese herbal medicine (CHM).In the past, clinical data showed that some herbs possessed anticancer properties, but western scientists have doubted the scientific validity of CHM due to the lack of scientific evidence from their perspective. Recently there have been encouraging results, from a western perspective, in the cancer research field regarding the anticancer effects of CHM. Experiments showed that CHM played its anticancer role by inducing apoptosis and differentiation, enhancing the immune system, inhibiting angiogenesis, reversing multidrug resistance (MDR), etc. Clinical trials demonstrated that CHM could improve survival, increase tumor response, improve quality of life, or reduce chemotherapy toxicity, although much remained to be determined regarding the objective effects of CHM in human in the context of clinical trials. Interestingly, both laboratory experiments and clinical trials have demonstrated that when combined with chemotherapy, CHM could raise the efficacy level and lower toxic reactions. These facts raised the feasibility of the combination of herbal medicines and chemotherapy, although much remained to be investigated in this area.

  18. Inhibition of Urogenital Chlamydia Trachomatis in Vitro by 12 Diuretic Traditional Chinese Medicines

    Institute of Scientific and Technical Information of China (English)

    LI Jianjun(李建军); TU Yuying(涂裕英); TONG Juzhen(佟菊贞); WANG Peitu(汪培土)

    2002-01-01

    Objective:To detect the inhibition of urogenital chlamydia trachomatis (CT) by 12 traditional Chinese medicines in vitro.Methods: The inhibition of CT isolates by these medicines was detected by micro-culture technique with McCoy cells in vitro.Results: All the diuretic traditional Chinese medicines inhibited urogenital CT. The minimum inhibitory concentrations (MICs) ranged from 0.122 mg ml-1 to 62.5 mg ml-1. Diathus superbus L., Poria cocos (Shcw.) Woft,Polyporus umbellatus (Pets.) Fries, and Artemisia capillaries Thunb showed stronger inhibition than the other eight traditional Chinese medicines. The numbers and sizes of inclusions bodies reduced gradually and disappeared finally with the increase of the concentrations.Conclusion: All the 12 diuretic traditional Chinese medicines inhibited urogenital CT.

  19. Effect of Chinese Herbal Medicine on Immunohistochemistry of Harder's Glands of Chickens

    Institute of Scientific and Technical Information of China (English)

    SHEN Ping; GAO Guisheng; SHI Qiumei; LI Min

    2009-01-01

    To investigate the mechanism of action of Chinese herbal medicine, the immunocells of Harder's glands were observed.The healthy Hy-Line Brown chickens of 12-day-old were divided into three groups randomly. The chickens in group 1 and 2 drank the water with 0.5% and 1% Chinese herbal medicine immunopromoter every day. The chickens in group 3 as control drank pure water. The Harder's glands of the chickens from 0.5% group, 1% group and control group at 24, 36 and 48 d after drinking medicine respectively were made into histological section. And then the histological sections were observed histologically. The results showed that Chinese herbal medicine could increase the quantity of the immunocells in glandular organs conspicuously. Immunopotentiator of Chinese herbal medicine could promote the amount and growth of secreted immunoglobuline and elevate the immune level of the organism, and the effect of 1% group was higher than that of 0.5% group.

  20. Integrating traditional Chinese medicine into mainstream healthcare system in Hong Kong, China-A model of integrative medicine in the HKU-SZ Hospital.

    Science.gov (United States)

    Lao, Lixing; Ning, Zhipeng

    2015-11-01

    The European Congress for Integrative Medicine 2015 Global Summit on Integrative Medicine and Healthcare in Greater Copenhagen has successfully promoted integrative medicine to the public once again. Integrative medicine, which is called the art and science of healthcare by Nordic Integrative Medicine, has been widely used in the world. In Hong Kong, integrated traditional Chinese and Western medicine, which is also known as the Chinese version of integrative medicine, provides a valuable reference for the development of integrative medicine in the world. In this article, we introduce the development of traditional Chinese medicine in Hong Kong and an integrated traditional Chinese and Western medicine model in the University of Hong Kong-Shenzhen Hospital.

  1. Integrating traditional Chinese medicine into mainstream healthcare system in Hong Kong, China-A model of integrative medicine in the HKU-SZ Hospital.

    Science.gov (United States)

    Lao, Lixing; Ning, Zhipeng

    2015-11-01

    The European Congress for Integrative Medicine 2015 Global Summit on Integrative Medicine and Healthcare in Greater Copenhagen has successfully promoted integrative medicine to the public once again. Integrative medicine, which is called the art and science of healthcare by Nordic Integrative Medicine, has been widely used in the world. In Hong Kong, integrated traditional Chinese and Western medicine, which is also known as the Chinese version of integrative medicine, provides a valuable reference for the development of integrative medicine in the world. In this article, we introduce the development of traditional Chinese medicine in Hong Kong and an integrated traditional Chinese and Western medicine model in the University of Hong Kong-Shenzhen Hospital. PMID:26559359

  2. Integrating traditional Chinese medicine into mainstream healthcare system in Hong Kong, China-A model of integrative medicine in the HKU-SZ Hospital

    Institute of Scientific and Technical Information of China (English)

    Lixing Lao; Zhipeng Ning

    2015-01-01

    The European Congress for Integrative Medicine 2015 Global Summit on Integrative Medicine and Healthcare in Greater Copenhagen has successfully promoted integrative medicine to the public once again. Integrative medicine, which is called the art and science of healthcare by Nordic Integrative Medicine, has been widely used in the world. In Hong Kong, integrated traditional Chinese and Western medicine, which is also known as the Chinese version of integrative medicine, provides a valuable reference for the development of integrative medicine in the world. In this article, we introduce the development of traditional Chinese medicine in Hong Kong and an integrated traditional Chinese and Western medicine model in the University of Hong Kong-Shenzhen Hospital.

  3. Materials science tools for regenerative medicine

    Science.gov (United States)

    Richardson, Wade Nicholas

    Regenerative therapies originating from recent technological advances in biology could revolutionize medicine in the coming years. In particular, the advent of human pluripotent stem cells (hPSCs), with their ability to become any cell in the adult body, has opened the door to an entirely new way of treating disease. However, currently these medical breakthroughs remain only a promise. To make them a reality, new tools must be developed to surmount the new technical hurdles that have arisen from dramatic departure from convention that this field represents. The collected work presented in this dissertation covers several projects that seek to apply the skills and knowledge of materials science to this tool synthesizing effort. The work is divided into three chapters. The first deals with our work to apply Raman spectroscopy, a tool widely used for materials characterization, to degeneration in cartilage. We have shown that Raman can effectively distinguish the matrix material of healthy and diseased tissue. The second area of work covered is the development of a new confocal image analysis for studying hPSC colonies that are chemical confined to uniform growth regions. This tool has important application in understanding the heterogeneity that may slow the development of hPSC -based treatment, as well as the use of such confinement in the eventually large-scale manufacture of hPSCs for therapeutic use. Third, the use of structural templating in tissue engineering scaffolds is detailed. We have utilized templating to tailor scaffold structures for engineering of constructs mimicking two tissues: cartilage and lung. The work described here represents several important early steps towards large goals in regenerative medicine. These tools show a great deal of potential for accelerating progress in this field that seems on the cusp of helping a great many people with otherwise incurable disease.

  4. Regulating Traditional Chinese Medicine Practitioners and Acupuncturists in Ontario, Canada

    Directory of Open Access Journals (Sweden)

    Glen E. Randall

    2015-12-01

    Full Text Available In 2006, the Ontario government passed the Traditional Chinese Medicine Act, which granted Traditional Chinese Medicine practitioners and Acupuncturists (TCM/A practitioners self-regulatory status under the Regulated Health Professions Act, 1991. The goal of the legislation was to create a new regulatory college that would set and enforce high standards of care and safety in order to enhance public protection and access to a range of traditional and alternative therapies. In April 2013, the College of Traditional Chinese Medicine Practitioners and Acupuncturists of Ontario was officially launched. Several factors account for the government’s decision to delegate self-regulatory authority to TCM/A practitioners through the creation of a regulatory college. In particular, the government’s decision seems to have been influenced by lobbying of some practitioners, greater public acceptance of alternative medicines, patient safety concerns related to acupuncture cases in the media, and the precedence of self-regulatory status being granted to these practitioners in other provinces. The degree to which the legislation has achieved its goals is difficult to determine given the short period of time the regulatory college has existed. However, the fact that the college has developed standards of practice to guide TCM/A practitioners and has a process in place to address public complaints is an early indication of movement toward achieving the policy’s goals. Le gouvernement de l'Ontario a fait voter en 2006 la Loi sur les praticiens en médecine traditionnelle chinoise, qui accorde aux praticiens en médecine traditionnelle chinoise et aux acupuncteurs (praticiens en MTC/A le statut de profession autonome dans le cadre la Loi sur les professions de la santé réglementées de 1991. Le but de la Loi était de créer un ordre professionnel capable d'établir et appliquer des normes de qualité et de sécurité des soins, ceci dans le but d

  5. Hypertension knowledge in urban elderly patients: comparison between adherents to traditional Chinese medicine and Western medicine

    Institute of Scientific and Technical Information of China (English)

    Jiangping Lin; Huining Lei; Fang Liu

    2008-01-01

    Objective To compare knowledge about hypertension between elderly Chinese urban patients with preferences for either traditional Chinese medicine (TCM) or Western medicine (WM).Methods Elderly (≥ 65 years old) patients with hypertension who prefer TCM treatment (n=112) or WM (n=126) were questioned about hypertension.Their answers were compared.Results Only 32.6% of participants correctly identified hypertension as a main risk factor of coronary heart disease and stroke,22.3% of patients answered that the main purpose of hypertension control was preventing cardiovascular disease.Other major reasons for these patients to seek medical treatment for their hypertension included:persuasion by physicians or their family members (21.6%),alleviating symptoms such as headache and dizziness (16.8%),lowering blood pressure without knowing specific reason (12.4%).The predictors for poor knowledge of hypertension were similar irrespective of preference for WM or TCM treatment,and included those with lower levels of education and older age.Television and newspaper (46.8%) were the most frequent sources of hypertension information for both groups.Among those who preferred TCM treatment,"TCM has fewer side effects than WM" and "TCM cures disease while WM only alleviates symptoms" were common beliefs held.Conclusion This study shows that knowledge of hypertension is similar among Chinese urban patients with preferences for either WM or TCM treatment and that misunderstandings about hypertension are common among the elderly patients.In order to control hypertension effectively,public health education is necessary.This should target those with a lower level of education and older age.

  6. Progress in Traditional Chinese and Western Medicine Treatments and Nursing Care of Knee Osteoarthritis

    Institute of Scientific and Technical Information of China (English)

    Xiao-Hua Shen; Yi Cui

    2015-01-01

    This paper reviews the causes of knee osteoarthritis, traditional Chinese and Western medicine therapies and nursing research progress and indicates that traditional Chinese and Western medicine have gradually recognized the cause of knee osteoarthritis. Knee osteoarthritis has been treated with various treatments and nursing care planning, and the combination of traditional Chinese and Western medicine has constantly been improved. Nurses should instruct the discharged patient to correctly treat their disease, adopt the health education, and, via the establishment of a healthy lif-estyle, insist on a functional exercise to relieve the pain, delay disease progression, and improve quality of life.

  7. Screening test for anti-Helicobacter pylori activity of traditional Chinese herbal medicines

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    AIM:To evaluate the anti-Helicobacter pylori (H.pylori) activity of 50 traditional Chinese herbal medicines in order to provide the primary evidence for their use in clinical practice.METHODS:A susceptibility test of water extract from 50 selected traditional Chinese herbal medicines for in vitro H.pylori Sydney strain 1 was performed with broth dilution method.Anti-H.pylori activity of the selected Chinese herbal medicines was evaluated according to their minimum inhibitory concentration (MIC).RESULTS:The ...

  8. Speech at the Meeting Commemorating the 50th Anniversary of Chairman MAO Ze-dong's Important Instruction on Western Medicine Doctors Learning Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    CHEN Zhu

    2009-01-01

    @@ Respected leaders, distinguished guests, venerable seniors and comrades, Today, the Meeting Commemorating the 50th Anniversary of Chairman MAO Ze-dong's Important Instructions on Western Medicine Doctors Learning Traditional Chinese Medicine was inaugurated by the Chinese Association of Integrative Medicine, and it is also an important occasion to review the past and look forward to the future.

  9. Prof. CHEN Ke-ji Winning the Prize of "Ren Ji Cup" for International Contribution to Chinese Medicine by WFCMS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ In order to promote the exchange and cooperation of Chinese medicine among the states and regions globally and fasten the step of Chinese medicine to the world, the World Federation of Chinese Medicine Societies (WFCMS) has set up an award for those who have greatly contributed to medical treatment, education, scientific research of Chinese medicine, and the establishment of the statutory registration of Chinese medicine. The First International Contribution to Chinese Medicine Award Ceremony was held on April 10 at the Great Hall of the People in China. Prof. CHEN Ke-ji (China), Lin Tzi Chang (Australia) and David Molony (U.S.A) were awarded "Ren Ji Cup", the Prize for International Contribution to Chinese Medicine.

  10. Establishing Chinese medicine characteristic tumor response evaluation system is the key to promote internationalization of Chinese medicine oncology.

    Science.gov (United States)

    Li, Jie; Li, Lei; Liu, Rui; Lin, Hong-sheng

    2012-10-01

    The features and advantages of Chinese medicine (CM) in cancer comprehensive treatment have been in the spotlight of experts both at home and abroad. However, how to evaluate the effect of CM more objectively, scientifically and systematically is still the key problem of clinical trial, and also a limitation to the development and internationalization of CM oncology. The change of tumor response evaluation system in conventional medicine is gradually consistent with the features of CM clinical effect, such as they both focus on a combination of soft endpoints (i.e. quality of life, clinical benefit, etc.) and hard endpoints (i.e. tumor remission rate, time to progress, etc.). Although experts have proposed protocols of CM tumor response evaluation criteria and come to an agreement in general, divergences still exist in the importance, quantification and CM feature of the potential endpoints. Thus, establishing a CM characteristic and wildly accepted tumor response evaluation system is the key to promote internationalization of CM oncology, and also provides a more convenient and scientific platform for CM international cooperation and communication.

  11. [A new strategy for Chinese medicine processing technologies: coupled with individuation processed and cybernetics].

    Science.gov (United States)

    Zhang, Ding-kun; Yang, Ming; Han, Xue; Lin, Jun-zhi; Wang, Jia-bo; Xiao, Xiao-he

    2015-08-01

    The stable and controllable quality of decoction pieces is an important factor to ensure the efficacy of clinical medicine. Considering the dilemma that the existing standardization of processing mode cannot effectively eliminate the variability of quality raw ingredients, and ensure the stability between different batches, we first propose a new strategy for Chinese medicine processing technologies that coupled with individuation processed and cybernetics. In order to explain this thinking, an individual study case about different grades aconite is provided. We hope this strategy could better serve for clinical medicine, and promote the inheritance and innovation of Chinese medicine processing skills and theories. PMID:26790315

  12. 用的理论开发新型中药%DEVELOPMENT OF NEW CHINESE MEDICINE WITH

    Institute of Scientific and Technical Information of China (English)

    吴凤锷; 吴蔚

    2002-01-01

    我们以现代科技理论为出发点,提出了新理论体系,试图使中外学者对中药的认识趋于一致.中药的本质就是"组合".无论是单方或复方都是一个庞大的分子库.具有相同或相似功能的分子组合成一个群体.这些群体表现出特定的药效."组合"有三层意思:生药的组合、活性分子群的组合与特定疗效的组合.分子群是特定药效功能的物质基础.就是从水平上研究中药及其药效的物质基础,阐明中药活性部位的相互作用与药效的相互关系及其作用机制.的三个新概念:中药功效分子族:具有相似药效作用的一类分子的组合,其骨架及功能团相同或相似.单味中药表征性组合分子:单味中药药效的代表性功效分子族,即主要药效分子组合.单味中药非表性组合分子:单味中药表征性分子以外的其它功效分子族,即辅助药效分子的组合.的主要研究范围:中药药效的组合分子学基础(植物化学,天然产物);组合分子的药理学基础(分子生物学,细胞生物学,药理学).本文提出了应用研究新型中药的新方法.%In order to expound "Chinese Medicine" with modern sciences and technology,we have suggested atween the west and east,it is difficult to study "Chinese Medicine" for the scholars in the west.activities. The "combination" means:The group of molecules is substantial base of the special activities.Some concepts have been given definitions. is chiefly concerned with the group of combinatorial molecules and thefunctions for "Chinese medicine", and its title reflects the prime importance of the insights that have come thecombinatorial molecules approach. A few important concepts have been included:molecules possessed same or similar activity.the"function unit"for efficeacy therapy of a sort of Chinese medicine(exp.A drug plant or other materials).Other "function units" except "Symbol combinatorial molecule".The research area of "combinatorial

  13. Principle, traits and functions of electrochemical fingerprint of Chinese traditional medicine

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In regard to such challenging analysis problems as scientific identification and quality evaluation of Chinese traditional medicine, the electrochemical fingerprint technique of Chinese traditional medicine has been researched. The principle, traits, functions, etc., of the electrochemical fingerprint have detailedly been analyzed and discussed by the B-Z oscillatory system using malonic acid as main dissipation substance, characterized by the fact that different influences of different Chinese traditional medicines on the mechanism of the oscillatory reaction cause different changes of the shape of the potential-time curve of the oscillatory system under the conditions of constant temperature and pressure. An economical, simple and convenient, easy pushing and effective scientific method for distinguishing and evaluating multifarious Chinese traditional medicines has successfully been put forward.

  14. Safety concerns of herbal products and traditional Chinese herbal medicines: Dehydropyrrolizidine alkaloids and aristolochic acid

    Science.gov (United States)

    In many countries, including the United States, herbal supplements, tisanes and vegetable products, including traditional Chinese medicines, are largely unregulated and their content is not registered, monitored or verified. Consequently, potent plant toxins including dehydropyrrolizidine alkaloids ...

  15. Effects and Mechanisms of Chinese Herbal Medicine in Ameliorating Myocardial Ischemia-Reperfusion Injury

    Directory of Open Access Journals (Sweden)

    Qing Liu

    2013-01-01

    Full Text Available Myocardial ischemia-reperfusion (MIR injury is a major contributor to the morbidity and mortality associated with coronary artery disease, which accounts for approximately 450,000 deaths a year in the United States alone. Chinese herbal medicine, especially combined herbal formulations, has been widely used in traditional Chinese medicine for the treatment of myocardial infarction for hundreds of years. While the efficacy of Chinese herbal medicine is well documented, the underlying molecular mechanisms remain elusive. In this review, we highlight recent studies which are focused on elucidating the cellular and molecular mechanisms using extracted compounds, single herbs, or herbal formulations in experimental settings. These studies represent recent efforts to bridge the gap between the enigma of ancient Chinese herbal medicine and the concepts of modern cell and molecular biology in the treatment of myocardial infarction.

  16. Thirty-five Infantile Purpura Nephritis Patients Treated with Integrated Traditional Chinese and Western Medicine

    Institute of Scientific and Technical Information of China (English)

    ZHENG; Tian-wen

    2001-01-01

    Thirty-five patients of infantile purpura nephritis (IPN) were treated with integrated traditional Chinese and western medicine (TCM-WM) from January 1994 to December 1998, with good efficacy obtained, and following is the report.

  17. Screening for hemostatic activities of popular Chinese medicinal herbs in vitro

    Directory of Open Access Journals (Sweden)

    Naoki Ohkura

    2015-03-01

    Conclusion Some popular Chinese medicinal herbs have potential as hemostatic agents and could thus be developed as new strategies for the treatment and prevention of bleeding. [J Intercult Ethnopharmacol 2015; 4(1.000: 19-23

  18. [Opportunity and challenge of post-marketing evaluation of traditional Chinese medicine].

    Science.gov (United States)

    Du, Xiao-Xi; Song, Hai-Bo; Ren, Jing-Tian; Yang, Le; Guo, Xiao-Xin; Pang, Yu

    2014-09-01

    Post-marketing evaluation is a process which evaluate the risks and benefits of drug clinical application comprehensively and systematically, scientific and systematic results of post-marketing evaluation not only can provide data support for clinical application of traditional Chinese medicine, but also can be a reliable basis for the supervision department to develop risk control measures. With the increasing demands for treatment and prevention of disease, traditional Chinese medicine has been widely used, and security issues are also exposed. How to find risk signal of traditional Chinese medicine in the early stages, carry out targeted evaluation work and control risk timely have become challenges in the development of traditional Chinese medicine industry. PMID:25532372

  19. Analysis of characters of bitter flavor in Chinese medicinal%苦味药材性状分析

    Institute of Scientific and Technical Information of China (English)

    纪玉佳; 王鹏; 李佳; 张永清; 滕佳林; 王振国

    2012-01-01

    Bitter flavor(taste) is an important part of the theory of Chinese herbal property. Different material composition not only aflect the medicinal characters,but also affect the the properties and flavors of Chinese materia medica. Total 1 728 Chinese medicinal which cold or heat property were described definitely in Herbal Medicine were selected. The relationship between bitter flavor and the characters was studied by using mathematical statistical methods. The results showed that the bitter flavor was effected by texture,flavor,taste,external color. The more crisp,bitter and astringent the Chinese medicinal is,the more bitter it is. The more sweet,salty,spicy and white the Chinese medicinal is,the less bitter it is.%苦味是中药药性理论的重要组成部分.不同的物质组成影响着药材性状,也影响着药材性味.选取《中华本草》所载1 728种寒热药性明确的中药,运用数学统计方法,研究了中药苦味与药材性状的关系,认为药材质地、气味、味道、外观颜色共同影响着中药苦味.药材性状质脆、味苦或味涩越多的中药,药材性味越偏向苦味;药材性状气香、味甘、味咸、味辛和白色越多的中药,药材性味越远离苦味.

  20. Effects of Traditional Chinese Patent Medicine on Essential Hypertension

    Science.gov (United States)

    Xiong, Xingjiang; Wang, Pengqian; Zhang, Yuqing; Li, Xiaoke

    2015-01-01

    Abstract Traditional Chinese patent medicine (TCPM) is widely used for essential hypertension (EH) in China. However, there is no critically appraised evidence, such as systematic reviews or meta-analyses, regarding the potential benefits and disadvantages of TCPM to justify their clinical use and recommendation. The aim of this review was to systematically evaluate and meta-analyze the effects of TCPM for EH. Seven databases, the Cochrane Library, PubMed, EMBASE, the China National Knowledge Infrastructure, the Chinese Scientific Journal Database, the Chinese Biomedical Literature Database, and the Wanfang Database, were searched from their inception to August 2014 for relevant studies that compared one TCPM plus antihypertensive drugs versus antihypertensive drugs alone. The methodological quality of the included trials was assessed using the Cochrane risk-of-bias tool. The primary outcome measures were mortality or progression to severe complications and adverse events. The secondary outcome measures were blood pressure (BP) and quality of life (QOL). Seventy-three trials, which included 8138 patients, on 17 TCPMs were included. In general, the methodological quality was low. Two trials evaluated the effects of TCPMs on mortality and the progression to severe complications after treatment, and no significant difference was identified compared with antihypertensive drugs alone. No severe adverse events were reported. Thirteen TCPMs used in complementary therapy significantly decreased systolic BP by 3.94 to 13.50 mmHg and diastolic BP by 2.28 to 11.25 mmHg. QOL was significantly improved by TCPM plus antihypertensive drugs compared with antihypertensive drugs alone. This systematic review provided the first classification of clinical evidence for the effectiveness of TCPM for EH. The usage of TCPMs for EH was supported by evidence of class level III. As a result of the methodological drawbacks of the included studies, more rigorously designed randomized

  1. Experimental Study on Resistance to Bacterial Toxin Role for Ten Kinds Chinese Herb Medicines with Clearing away Heat and Toxic Material in Guangdong Area%10种广东本地清热解毒中草药抗细菌内毒素作用实验研究

    Institute of Scientific and Technical Information of China (English)

    张健民; 蒋三元; 李雁玲; 郑国燊; 唐荣德

    2011-01-01

    Objective: Explore the role of resistance to bacterial endotoxin for ten kinds Chinese herb medicines with the clearing away heat and toxic material in Guangdong area. Methods: The limulus reagent tests were used in vitro anti -endotoxin agglutinate reaction experiment. Results; Ten kinds Chinese herb medicines with the clearing away heat and toxic material in Guangdong area all have tuba] agglutinate reactions of resistance to limulus reagent ( namely, all have anti - bacterial endotoxin actions) when the concentration is in 1.0g/mL. Other Chinese herb medicines have anti - bacterial endotoxin actions besides Jin niu kou and Xi huang cao when the concentration is in 0.5g/mL and besides Jin niu kou.Xi huang cao and Gang mei gen when the concentration is in 0. 3g/mL. Tian ji huang,Hu lu cha and Jiu bi ying have anti - bacterial endotoxin actions when the concentration is in 0. Lg/mL. These results point out that the various medicinal materials have different anti - bacterial endotoxin actions. Conclusions: Ten kinds Chinese herb medicines with the clearing away heat and toxic material in Guangdong area all have the roles of resistance to bacterial endotoxin. Tian ji huang、Hu lu cha and Jiu bi ying have strongest actions. Jin niu kou, Xi huang cao have relatively weak actions.%目的:探讨10种广东本地清热解毒中草药的抗细菌内毒素作用.方法:采用鲎试剂试管凝集反应进行体外抗内毒素实验.结果:所研究的10种广东本地清热解毒中草药,药液浓度为1.0g/mL时,10种中草药均有抗鲎试剂试管凝集反应,均具有抗细菌内毒素的作用;调整浓度为0.5g/mL时,除金扭扣、溪黄草外,其余中草药具有抗细菌内毒素作用;浓度为0.3g/mL时,除金扭扣、溪黄草、岗梅根外,其余中草药具有抗细菌内毒素作用;浓度为0.1g/mL时,田基黄、葫芦茶、救必应具有抗细菌内毒素作用,提示不同的药材存在抗细菌内毒素作用的差异.结论:广东10种本地清

  2. Prescriptions of Chinese Herbal Medicines for Insomnia in Taiwan during 2002

    OpenAIRE

    Fang-Pey Chen; Maw-Shiou Jong; Yu-Chun Chen; Yen-Ying Kung; Tzeng-Ji Chen; Fun-Jou Chen; Shinn-Jang Hwang

    2011-01-01

    Chinese herbal medicine (CHM) has been commonly used for treating insomnia in Asian countries for centuries. The aim of this study was to conduct a large-scale pharmaco-epidemiologic study and evaluate the frequency and patterns of CHM use in treating insomnia. We obtained the traditional Chinese medicine (TCM) outpatient claims from the National Health Insurance in Taiwan for the year 2002. Patients with insomnia were identified from the diagnostic code of International Classification of Dis...

  3. [Research on our hospital inventory management status quo of traditional Chinese medicine drugs and treatment method].

    Science.gov (United States)

    Zhang, Ying-Nan; Xu, Wen

    2014-03-01

    Under the background of the new medical reform, a large variety of traditional Chinese medicine from complicated sources, Chinese traditional medicine of actor of true and false of the quality directly affect the drug safety and clinical efficacy, but also relate to the social and economic benefits of hospital. Along with the development of the modern management of medical institutions and drug circulation circulation system reform in our country, the hospital drug inventory, supply and management work is an important topic for the pharmaceutical trading. However, there is always contradiction, dispensary need to supple pharmacy, in order to satisfy the demands of hospital patients with normal diagnosis and treatment work. However, if the drug inventory is too much, not only increases the drug monitoring problem, at the same time, but also causes storage costs rise. Therefore, completing scientific and reasonable storage and management becomes urgent problems at present. Wherefore, our country administration of traditional Chinese medicine in 2007 promulgated the "Chinese traditional medicine yinpian management norms in hospital", aims to standardize management of Chinese traditional medicine quality and improve the safety of drugs. The author through looking up information and visiting survey, to understand the currently existing problems, and summarizes the literature inland and abroad in recent years Chinese medicine drug inventory management work experience, in view of status quo of Chinese medicine inventory management in China, put forward the solution. To guarantee TCM pharmacy management more standardized, more standard, to adapt to the new reform of Chinese traditional medicine industry, improve the management level of hospital, defend the hospital's reputation and the patient's interests.

  4. CLINICAL OBSERVATION ON TREATMENT OF CHRONIC PHARYNGITIS WITH ACUPUNCTURE PLUS CHINESE HERBAL MEDICINES

    Institute of Scientific and Technical Information of China (English)

    聂荣华

    2003-01-01

    @@ Chronic pharyngitis is the diffuse inflammation of the pharyngeal mucus, submucosal and lymph tissues. Traditional Chinese medicine (TCM) considers it to be the category of "Meiheqi" (梅核气,globus hystericus), "Shiyin" (失音,aphonia) and "Houbi" (喉痹,inflammation of the throat). According to the theory of TCM, the author of the present paper adopted acupuncture plus Chinese herbal medicines to treat it from 1990 to 2002, and achieved a satisfactory result. It is reported as follows.

  5. Antiviral Activities of Several Oral Traditional Chinese Medicines against Influenza Viruses

    OpenAIRE

    Lin-Lin Ma; Miao Ge; Hui-Qiang Wang; Jin-Qiu Yin; Jian-Dong Jiang; Yu-Huan Li

    2015-01-01

    Influenza is still a serious threat to human health with significant morbidity and mortality. The emergence of drug-resistant influenza viruses poses a great challenge to existing antiviral drugs. Traditional Chinese medicines (TCMs) may be an alternative to overcome the challenge. Here, 10 oral proprietary Chinese medicines were selected to evaluate their anti-influenza activities. These drugs exhibit potent inhibitory effects against influenza A H1N1, influenza A H3N2, and influenza B virus...

  6. [Analyses on positive influence of harmonous development of traditional Chinese medicine compounds' researchs and patent protection].

    Science.gov (United States)

    Yang, Xujie; Xiao, Shiying; Guo, Zan; Wang, Zhimin; You, Yun

    2012-01-01

    Current patent protection of traditional Chinese medicine (TCM) compounds is far from being satisfactory with increasing research and development achievements. As patent protection of traditional Chinese medicine compounds is closely related with many fields such as research and development of new TCM drugs, industrial development and TCM internationalization, the development of research and harmonious development of TCM compounds and their patent protection is bound to have a far-reaching influence on domestic and even international societies. PMID:22741453

  7. A meta-analysis of Chinese herbal medicines for vascular dementia

    Institute of Scientific and Technical Information of China (English)

    Xiude Qin; Yu Liu; Yanqing Wu; Shuo Wang; Dandan Wang; Jinqiang Zhu; Qiaofeng Ye; Wei Mou; Liyuan Kang

    2013-01-01

    OBJECTIVE: To investigate the efficacy and safety of Chinese herbal medicines in the treatment of patients with vascular dementia.DATA RETRIEVAL: We retrieved publications from Cochrane Library (2004 to July 2011), PubMed (1966 to July 2011), the Chinese Science and Technique Journals Database (1977 to July 2011), the China National Knowledge Infrastructure (1979 to July 2011), Google Scholar (July 2011), and the Chinese Biomedical Database (1977 to July 2011) using the key words "Chinese medicine OR Chinese herbal medicine" and "vascular dementia OR mild cognition impair OR multi-infarct dementia OR small-vessel dementia OR strategic infarct dementia OR hypoperfusion dementia OR hemorrhagic dementia OR hereditary vascular dementia".MAIN OUTCOME MEASURES: Effective rate, Mini-Mental State Examination scores, Hasegawa Dementia Scale scores, and incidence of adverse reactions.CONCLUSION: Chinese herbal medicine appears to be safer and more effective than control measures in the treatment of vascular dementia. However, the included trials were generally low in quality. More well-designed, high-quality trials are needed to provide better evidence for the assessment of the efficacy and safety of Chinese medicines for vascular dementia.

  8. Evaluation of Antioxidant and Antimicrobial Activities from 28 Chinese Herbal Medicines

    Directory of Open Access Journals (Sweden)

    Ho-Yang Lin

    2013-05-01

    Full Text Available Background: Many Chinese medicines have been reported to exhibit high antimicrobial and antioxidantactivities. In this study, 28 traditional Chinese herbal medicines were tested for their antioxidant and antibacterial activities.Materials and Methods: Total flavonoid content of the ethanol extracts were determined by a colorimetric method. Total phenol content was estimated as gallic acid equivalents. The antioxidant activities of the extracts were evaluated by various antioxidant assays, including 1,1-diphenyl-2-picrylhydrazyl (DPPH radical scavenging, troloxequivalent antioxidant capacity (TEAC and reducing power. In addition to the antioxidant activity, the antimicrobial assay was measured as well. Six strains of the clinical antibiotic resistant pathogens includingEscherichia coli, Staphylococcus aureus, methicine resistant Staphylococcus aureus (MRSA, ornithine resistant Staphylococcus aureus (ORSA, Pseudomonas aeruginosa, and Acinetobacter baumannii were used in the tests.Results: Among the extracts screened, Artemisia vulgaris and Sanguisorba officinalis showed the best antioxidant performance in all the tested methods.In vitro antibacterial activity, the extracts of Paeonia suffruticosa and Cinnamomum cassia displayed a broad antimicrobial spectrum and significantantimicrobial activities, with inhibition zones between 14-28 mm, minimum inhibitory concentration (MIC between 0.9-5.2 mg/mL, and minimum bactericidal concentration (MBC between 1.0-5.7 mg/mL. Conclusion: These data suggest that Artemisia vulgaris and Sanguisorba officinalis may be effective potential sources of natural antioxidants, and Paeoniasuffruticosa and Cinnamomum cassia are potent inhibitors of antibiotic resistant pathogens.

  9. Traditional Chinese medicine in diagnosis and treatment of fibromyalgia syndrome.

    Science.gov (United States)

    Aliyev, R; Vieth, T; Geiger, G

    2010-11-01

    Fibromyalgia Syndrome (FS) is known for the difficulties arising from classification. The accompanying pain in skeletal muscles, myofascial peri-articular structures and a number of polymorphic symptoms cannot be separated into complexes of symptoms. The application of principles of Traditional Chinese Medicine (TCM) helps in analyzing the symptoms of FS to detect a leading syndrome and thereby establish an individual therapy. Medical histories and objective examinations of 25 patients with FS and 22 patients with vertebrogenic pain syndromes were analyzed according to TCM. A questionnaire was used to determine the leading constitutional type according to the 5-elements-theory. Analyses of the results showed that 83% of patients with FS were of constitutional type of the element earth. The following syndromes were found to be important in FS: 1) liver-Qi-stagnation, 2) Yin and blood deficiency of the liver, 3) Yang-weakness of the spleen and kidney, 4) Yin-weakness of the kidney. Applying TCM for FS allows for separating a group of symptoms and thus individual therapy. The determination of the constitutional type according to the 5-elements-theory may be used for a better understanding of the disharmony pattern.

  10. The Progress of Metabolomics Study in Traditional Chinese Medicine Research.

    Science.gov (United States)

    Wang, Pengcheng; Wang, Qiuhong; Yang, Bingyou; Zhao, Shan; Kuang, Haixue

    2015-01-01

    Traditional Chinese medicine (TCM) has played important roles in health protection and disease treatment for thousands of years in China and has gained the gradual acceptance of the international community. However, many intricate issues, which cannot be explained by traditional methods, still remain, thus, new ideas and technologies are needed. As an emerging system biology technology, the holistic view adopted by metabolomics is similar to that of TCM, which allows us to investigate TCM with complicated conditions and multiple factors in depth. In this paper, we tried to give a timely and comprehensive update about the methodology progression of metabolomics, as well as its applications, in different fields of TCM studies including quality control, processing, safety and efficacy evaluation. The herbs investigated by metabolomics were selected for detailed examination, including Anemarrhena asphodeloides Bunge, Atractylodes macrocephala Kidd, Pinellia ternate, etc.; furthermore, some valuable results have been obtained and summarized. In conclusion, although the study of metabolomics is at the early phase and requires further scrutiny and validation, it still provides bright prospects to dissect the synergistic action of multiple components from TCM. Overall, with the further development of analytical techniques, especially multi-analysis techniques, we expect that metabolomics will greatly promote TCM research and the establishment of international standards, which is beneficial to TCM modernization. PMID:26477800

  11. Treatment of Acute Lymphoblastic Leukemia from Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Ya-Li Hsiao

    2014-01-01

    Full Text Available Acute lymphoblastic leukemia (ALL is a cancer that immature white blood cells continuously overproduce in the bone marrow. These cells crowd out normal cells in the bone marrow bringing damage and death. Methotrexate (MTX is a drug used in the treatment of various cancer and autoimmune diseases. In particular, for the treatment of childhood acute lymphoblastic leukemia, it had significant effect. MTX competitively inhibits dihydrofolate reductase (DHFR, an enzyme that participates in the tetrahydrofolate synthesis so as to inhibit purine synthesis. In addition, its downstream metabolite methotrexate polyglutamates (MTX-PGs inhibit the thymidylate synthase (TS. Therefore, MTX can inhibit the synthesis of DNA. However, MTX has cytotoxicity and neurotoxin may cause multiple organ injury and is potentially lethal. Thus, the lower toxicity drugs are necessary to be developed. Recently, diseases treatments with Traditional Chinese Medicine (TCM as complements are getting more and more attention. In this study, we attempted to discover the compounds with drug-like potential for ALL treatment from the components in TCM. We applied virtual screen and QSAR models based on structure-based and ligand-based studies to identify the potential TCM component compounds. Our results show that the TCM compounds adenosine triphosphate, manninotriose, raffinose, and stachyose could have potential to improve the side effects of MTX for ALL treatment.

  12. New Effective Treatment of Liver Fibrosis by Chinese Herbal Medicine

    Institute of Scientific and Technical Information of China (English)

    张国梁

    2002-01-01

    @@ Liver fibrosis is an abnormal proliferation pathologic process of intrahepatic fibrous connective tissue that occurs after liver cells have been necrotized and stimulated by inflammatory factors. It is called fibrosis when the pathological change is mild, and liver cirrhosis when the change becomes so severe as to reconstruct the liver lobuli to form pseudolobuli and nodule(1). Liver fibrosis is an important pathological characteristic of chronic hepatopathy and the chief intermediate link to further develop of liver cirrhosis. No ideal remedy for treatment of chronic hepatitic cirrhosis has been found so far. Although some drugs, such as colchicine and penicillamine, had been reported to have the effect of fibrosis inhibition, their clinical application is still limited for the rather severe toxic-side effects. Certain progress have been made from the clinical and experimental studies on anti-fibrosis treatment by traditional Chinese medicine (TCM) carried out widely in China in recent ten years. And here is a general review of the drugs used.

  13. Insomnia in Chinese Medicine: The Heart of the Matter.

    Science.gov (United States)

    O'Brien, Kylie; Weber, Daniel

    2016-09-01

    Chronic insomnia affects a significant proportion of the general population worldwide, and is associated with several serious medical conditions. From the Western scientific literature, hyper-arousal (on the cognitive-emotional, behavioral, autonomic, or central nervous system level) is a final common pathway involved in its pathogenesis. However, from a Chinese medicine (CM) perspective, it is the Heart, capitalized to denote the functional system as described in CM theory, that is the key organ involved in insomnia due to its role as the "seat of consciousness." This article explores how insomnia is understood from the CM perspective, in particular the role of the Heart, and some of the neurophysiological evidence that supports these ancient theoretical understandings. The potential role of the vagus nerve and its relationship with the (biomedical) heart and CM Heart is also examined. Finally, some of the evidence in association with mechanisms of action of acupuncture in insomnia, in particular its impact on cardiovascular variables associated with insomnia, is presented, along with findings of systematic reviews. PMID:27526331

  14. The mechanisms in treatment of acute pancreatitis by traditional Chinese medicine

    Institute of Scientific and Technical Information of China (English)

    Xiping Zhang; Ying Wang; Yan Shi

    2006-01-01

    As common acute abdomen, most of acute pancreatitis(AP) are self-restricted. Only a few patients may develop into worse state with local complications or organ failures, and finally neastic acute pancreatitis (NAP). With the change of people's dietaries, cholelithiasis morbidity and popularization of wine in recent years, the number of AP patients has increased.Although people conducted enormous studies on pathogenesis of AP and brought forward many be valuable theories, yet the exact mechanism is still unclear by far. There are many therapies of AP which should be unexceptionally classified as operative therapy and non-operative therapy. With the increasing understanding of the disease in recent years, we found many defects of operation and good therapeutic effects of traditional Chinese medicine in AP. Traditional Chinese medicine as an auxiliary therapy has been generally paid close attention in clinical practices. Traditional Chinese medicine is a treasure-house of China. This article summarizes the main mechanisms of AP treatment by traditional Chinese medicine and the progress of laboratory studies. It aims to help people recognize the multiple-target treatment effects and conspicuous efficacy of traditional Chinese medicine and promote the popularization of traditional Chinese medicine in AP treatment.

  15. Quality and safety of Chinese herbal medicines guided by a systems biology perspective

    NARCIS (Netherlands)

    Wang, J.; Heijden, R. van der; Spruit, S.; Hankermeier, T.; Chan, K.; Greef, J. van der; Xu, G.; Wang, M.

    2009-01-01

    Chinese herbal medicines, often referred as Chinese materia medica (CMM), are comprised of a complex multicomponent nature. The activities are aimed at the system level via interactions with a multitude of targets in the human body. This review aims at the toxicity aspects of CMM and its preparation

  16. Meeting Minutes of International Conference on Prevention and Treatment of Acquired Immune Deficiency Syndrome with Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    LI Yong; WANG Jie; LIN Hong-sheng; WU Xin-fang; LIU Jie; TANG Yan-li; NAN Ji-hong

    2011-01-01

    @@ The International Conference on Prevention and Treatment of Acquired Immune Deficiency Syndrome (AIDS) with Chinese Medicine (CM) was held in Beijing International Hotel from October 16to 17,2010.It was cosponsored by Guang'anmen Hospital,China Academy of Chinese Medical Sciences (CACMS),and the First Affiliated Hospital of Henan University of Traditional Chinese Medicine.

  17. Book Review on the Illustrated Seeds of Chinese Medicinal Plants

    Institute of Scientific and Technical Information of China (English)

    Guo QS; Wang QY; Liu L; HE Shan-an

    2010-01-01

    @@ Medicinal plants are important source for Oriental and Western medicines. There are more than 500 herbs commonly used today in China, in which near 30% of them are seed medicines and over 65% are propagated from seed.

  18. [Study on characteristics of pharmacological effects of traditional Chinese medicines distributing along stomach meridian based on medicinal property combination].

    Science.gov (United States)

    Zhang, Bai-Xia; Gu, Hao; Guo, Hong-Ling; Ma, Li; Wang, Yun; Qiao, Yan-Jiang

    2014-07-01

    At present, studies on traditional Chinese medicine (TCM) properties are mostly restricted to a single or two kinds of medicinal properties, but deviated from the holism of the theoretical system of TCMs. In this paper, the characteristics of pharmacological effects of different property combinations of TCMs distributing in the stomach meridian were take as the study objective. The data of properties of TCMs distributing in the stomach meridian was collected from the Pharmacopoeia of the People's Republic of China (2005). The data of pharmacological effects of TCMs distributing in the stomach meridian was collected from all of literatures recorded in Chinese Journal Full-text Database (CNKI) since 1980, Science of Chinese Materia Medica (Yan Zhenghua, People's Medical Publishing House, 2006) and Clinical Science of Chinese Materia Medica (Gao Xuemin, Zhong Gansheng, Hebei Science and Technology Publishing House, 2005). The corresponding pharmacological effects of property combinations of TCMs distributing in the stomach meridian was mined by the method of association rules. The results of the association rules were consistent with the empirical knowledge, and showed that different medicinal property combinations had respective pharmacological characteristics, including differences and similarities in pharmacological effects of different medicinal property combinations. Medicinal property combinations with identical four properties or five tastes showed similar pharmacological effects; whereas medicinal property combinations with different four properties or five tastes showed differentiated pharmacological effects. However, medicinal property combinations with different four properties or five tastes could also show similar pharmacological effects. In this study, the medicinal property theory and the pharmacological effects of TCMs were combined to reveal the main characteristics and regularity of pharmacological effects of TCMs distributing in the stomach meridian

  19. Identification of herbal medicinal materials using DNA barcodes

    Institute of Scientific and Technical Information of China (English)

    Ming LI; Hui CAO; Paul Pui-Hay BUT; pang-Chui SHAW

    2011-01-01

    Herbal medicinal materials have been used worldwide for centuries to maintain health and to treat disease. However, adulteration of herbal medicines remains a major concern of users and industry for reasons of safety and efficacy. Identification of herbal medicinal materials by DNA technology has been widely applied,started from the mid-1990s. In recent years, DNA barcoding of global plant species using four standard barcodes (rbcL, matK, trnH-psbA and ITS) has been a major focus in the fields of biodiversity and conservation. These DNA barcodes can also be used as reliable tools to facilitate the identification of herbal medicinal materials for the safe use of herbs, quality control, and forensic investigation. Many studies have applied these DNA barcodes for the identification of herbal medicinal species and their adulterants. The present article reviews efforts in the identification of herbal medicinal materials using the standard DNA barcodes and other DNA sequence-based markers.

  20. Retinitis Pigmentosa Treatment with Western Medicine and Traditional Chinese Medicine Therapies.

    Science.gov (United States)

    Xu, Jian; Peng, Qinghua

    2015-01-01

    Current management of retinitis pigmentosa (RP) includes an attempt at slowing down the degenerative process through therapies that use either Western or traditional Chinese medicine (TCM). Novel therapies in Western medicine (WM) include use of tailor-made gene therapy, transplantation of stem cells, or neuroprotection treatment. TCM treatment includes two major approaches. These are orally applied herbal decoctions and acupuncture. In fact, all TCM treatments are based on the differentiation of a symptom-complex, which is the characteristic essence of TCM. Thus, diagnosed RP may be treated via the liver, the kidney, and the spleen. The principle behind these treatments is to invigorate the blood and brighten the eyes by toning up the liver and the kidney. Also treatments to cope with deficiencies in the two concepts that are unique and fundamental to TCM are considered: Qi or "vital energy" and Yin and Yang or the harmony of all the opposite elements and forces that make up existence. In particular, the Qi deficiency that results from blood stasis is addressed in these treatments. This paper also puts forward the existing problems and the prospect of the future development on integrating TCM with WM. PMID:26124961

  1. Teaching Material Culture and Chinese Gardens at American Colleges

    Directory of Open Access Journals (Sweden)

    Li Han

    2012-11-01

    Full Text Available The paper reflects on the experience of designing and teaching a course on material culture and Chinese gardens. Involving traditional philosophy, ethics, religion, painting, calligraphy, craft, literature, architecture and horticulture, a classical Chinese garden can be considered a microcosm of Chinese culture. This essay discusses the textbooks and general organization of the course, particularly focusing on how students study the key elements (rocks, water, plants and architecture in building a Chinese garden. Some Chinese literature with representations of gardens that can be used for this class is also introduced. In addition, this essay uses two classical Chinese gardens built in the United States (the Astor Court and the Garden of Flowing Fragrance to discuss the appropriation of “Chinese-ness” in different geographical, physical and cultural environments. Finally, some available online resources and technologies that have enhanced student understanding of the subject matter are introduced.

  2. Using the Theory of Planned Behaviour to Explain Use of Traditional Chinese Medicine among Hong Kong Chinese in Britain

    Directory of Open Access Journals (Sweden)

    Tina L. Rochelle

    2015-01-01

    Full Text Available The UK Chinese are known for their underutilisation of western healthcare services. Reasons for this underutilisation are complex. The Theory of Planned Behaviour (TPB is a widely used model of social cognition, which in the present study is being applied to traditional Chinese medicine (TCM utilisation and satisfaction with TCM services. Two hundred and seventy-two UK Chinese aged between 15 and 91 years (M=46.55; SD = 18.53 enrolled in the study. TCM utilisation was associated with gender, age, cultural attachment, and subjective norms. TCM users were more likely to be female and older and have a strong attachment to Chinese culture, and be influenced by the views of important others. Findings highlight the potential of the TPB in exploring TCM utilisation, whilst also throwing light on other factors influential in the use of TCM and satisfaction with TCM service provision among Chinese in the UK.

  3. Using the Theory of Planned Behaviour to Explain Use of Traditional Chinese Medicine among Hong Kong Chinese in Britain.

    Science.gov (United States)

    Rochelle, Tina L; Shardlow, Steven M; Ng, Sik Hung

    2015-01-01

    The UK Chinese are known for their underutilisation of western healthcare services. Reasons for this underutilisation are complex. The Theory of Planned Behaviour (TPB) is a widely used model of social cognition, which in the present study is being applied to traditional Chinese medicine (TCM) utilisation and satisfaction with TCM services. Two hundred and seventy-two UK Chinese aged between 15 and 91 years (M = 46.55; SD = 18.53) enrolled in the study. TCM utilisation was associated with gender, age, cultural attachment, and subjective norms. TCM users were more likely to be female and older and have a strong attachment to Chinese culture, and be influenced by the views of important others. Findings highlight the potential of the TPB in exploring TCM utilisation, whilst also throwing light on other factors influential in the use of TCM and satisfaction with TCM service provision among Chinese in the UK. PMID:26504477

  4. Comparison on Temperament Theory between Traditional Chinese Medicine and Modern Psychology

    Institute of Scientific and Technical Information of China (English)

    SHI Le

    2002-01-01

    This study has explained and compared temperament theory between traditional Chinese medicine and modernrn psychology on five aspects of concept, characteristics, classification, influential factors and practical significance. And we thought that this study had guiding effect on clinical practice under the new medicine model.

  5. Integrative Chinese and Western Medicine Approach In Treating 64 Patients with Anovular Infertility

    Institute of Scientific and Technical Information of China (English)

    严凤; 张继华; 李瑞芳; 宋兰萍

    2003-01-01

    @@ Sixty-four women with anovular infertility were treated with the integrative Chinese and western medicine (ICWM) approach in our hospital from December 1997 to December 1998. Compared them with 50 women who were treated with Western Medicine (WM) alone, the difference was significant, the report is as follows.

  6. [Treatment of type 2 diabetes mellitus oral Chinese patent medicine literature metrology analysis].

    Science.gov (United States)

    Cui, Tong-hua; Li, Yuan-yuan

    2012-09-01

    The CBM, CNKI database 1979-2012 included oral Chinese patent medicine treatment diabetes literature, and the literature published time, periodical distribution, sources of literature and statistical analysis, to explore the treatment of type 2 diabetes medicine clinical literature distribution law and development trend, as in diabetes research related to the clinical and scientific research personnel to provide reference. PMID:23236770

  7. Tonic Herbs and Herbal Mixtures in Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Thomas Efferth

    2016-01-01

    Full Text Available This review results from a PubMed-based data-mining of scientific literature concerning typical tonic herbs and formulas of Chinese herbal medicine and their application principle under the theory of CM. We have focused on two aspects of tonic activity: body tonification against qi气-, blood血-, yin阴- and yang阳-deficiency, respectively, and organ (Zang 脏and Fu腑 tonification against heart-, liver-, spleen/stomach-, lung-, and kidney-deficiency, respectively. Body-tonifying herbs are: Astragalus Membranaceus Radix (Huang-qi黄芪 and Panax Ginseng Radix (Ren-shen人参 for qi-tonification; Angelicae Sinensis Radix (Dang-gui当归 and Rehmannia Glutinosa Radix Preparata (Shu-di熟地 for blood-tonification; Ophiopogon Japonicus Radix (Mai-dong麦冬 and Scrophularia Ningpoensis Radix (Xuan-shen玄参 for yin-deficiency; Myristica Fragrans Semen (Rou-dou-kou肉豆蔻 and Psoralea Corylifolia Fructus (Bu-gu-zhi补骨脂 for yang-deficiency. The corresponding CM formulas are: Bu-zhong-yi-qi decoction (补中益气汤 for qi-tonification; Si-wu decoction (四物汤 for blood-tonification; Zeng-ye decoction (增液汤 for yin-tonification; Si-shen pill (四神丸 for yang-tonification. Organ-tonifying herbs are: Glycyrrhizae Uralensis Radix Preparata (Zhi-gan-cao炙甘草 and Rehmannia Glutinosa Radix (Di-huang地黄 for heart-tonification; Lycium Barbarum Fructus (Gou-qi-zi枸杞子 and Angelicae Sinensis Radix (Dang-gui当归 for liver-tonification; Panax Ginseng Radix (Ren-shen人参 and Atractylodis Macrocephala Rhizoma (Bai-zhu白术 for spleen/stomach-tonification; Panax Ginseng Radix (Ren-shen人参 and Astragalus Membranaceus Radix (Huang-qi黄芪 for lung-tonification; Cornus Officinalis Fructus (Shan-zhu-yu山茱萸 and Dioscorea Opposite Rhizoma (Shan-yao山药 for kidney-tonification. The corresponding CM formulas are: Zhi-gan-cao decoction (炙甘草汤 for heart-tonification; Yi-guan decoction (一贯煎 for liver

  8. Applications of HPLC/MS in the analysis of traditional Chinese medicines%Applications of HPLC/MS in the analysis of traditional Chinese medicines

    Institute of Scientific and Technical Information of China (English)

    Miao Li; Xiao- Fang Hou; Jie Zhang; Si-Cen Wang; Qiang Fu; Lang- Chong He

    2011-01-01

    In China, traditional Chinese medicines (TCMs) have been used in clinical applications for thousands of years. The successful hyphenation of high-performance liquid chromatography (HPLC) and mass spectrometry (MS) has been applied widely in TCMs and biolo

  9. Review of the use of botanicals for epilepsy in complementary medical systems--Traditional Chinese Medicine.

    Science.gov (United States)

    Xiao, Fenglai; Yan, Bo; Chen, Lei; Zhou, Dong

    2015-11-01

    In traditional Chinese medicine, botanical remedies have been used for centuries to treat seizures. This review aimed to summarize the botanicals that have been used in traditional Chinese medicine to treat epilepsy. We searched Chinese online databases to determine the botanicals used for epilepsy in traditional Chinese medicine and identified articles using a preset search syntax and inclusion criteria of each botanical in the PubMed database to explore their potential mechanisms. Twenty-three botanicals were identified to treat epilepsy in traditional Chinese medicine. The pharmacological mechanisms of each botanical related to antiepileptic activity, which were mainly examined in animal models, were reviewed. We discuss the use and current trends of botanical treatments in China and highlight the limitations of botanical epilepsy treatments. A substantial number of these types of botanicals would be good candidates for the development of novel AEDs. More rigorous clinical trials of botanicals in traditional Chinese medicine for epilepsy treatment are encouraged in the future. This article is part of a Special Issue entitled "Botanicals for Epilepsy".

  10. Marketing strategy for a traditional Chinese medicine (TCM) clinic in Vancouver

    OpenAIRE

    Janjua, Qaiser Rashid

    2006-01-01

    Complementary and Alternative Medicine (CAM) has gained worldwide acceptance in the recent past. Apart from all other modalities of CAM, Traditional Chinese Medicine (TCM) has gained enormous interest globally. TCM has become a mainstream medicine in several underdeveloped countries and is rapidly gaining recognition in developed countries such as in the U.S and especially Canada. British Columbia is the only jurisdiction in North America that officially recognizes TCM. Consequently, the loca...

  11. 中药退热机制研究进展%Research Progress of Antipyretic Mechanism of Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    韩庆荣; 张永科; 刘明云

    2013-01-01

    Objective:Tò summarize the antipyretic mechanism of traditional Chinese medicine.Methods:Retrieve and analyze relevant literature about antifebrile by traditional Chinese medicine.Results:Single traditional Chinese medicine and Chinese medicine formula have certain superiority in the treatment of febrile disease.Chinese medicine for antipyretic is variety in resources.Conclusion:The antifebrile effect of traditional Chinese medicine is better.%目的:探讨中药的退热机制.方法:检索有关中医药退热方面的文献,并进行分析.结果:单味中药、中药组方对于发热疾病的治疗有一定的优越性,中药解热药种类繁多,资源丰富.结论:中医药退热效果较好.

  12. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Ming; Wang, Ning; Tan, Hor Yue [School of Chinese Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong (China); Tsao, Sai-Wah [Department of Anatomy, Li KaShing Faculty of Medicine, The University of Hong Kong, Hong Kong (China); Feng, Yibin, E-mail: yfeng@hku.hk [School of Chinese Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong (China)

    2015-08-24

    In recent decades Chinese medicine has been used worldwide as a complementary and alternative medicine to treat cancer. Plenty of studies have shown that microRNAs (miRNAs) play fundamental roles in many pathological processes, including cancer, while the anti-cancer mechanisms of Chinese medicinal herbs targeting miRNAs also have been extensively explored. Our previous studies and those of others on Chinese medicinal herbs and miRNAs in various cancer models have provided a possibility of new cancer therapies, for example, up-regulating the expression of miR-23a may activate the positive regulatory network of p53 and miR-23a involved in the mechanism underlying the anti-tumor effect of berberine in hepatocellular carcinoma (HCC). In this review, we survey the role of Chinese medicinal herbal products in regulating miRNAs in cancer and the use of mediating miRNAs for cancer treatment. In addition, the controversial roles of herb-derived exogenous miRNAs in cancer treatment are also discussed. It is expected that targeting miRNAs would provide a novel therapeutic approach in cancer therapy by improving overall response and survival outcomes in cancer treatment, especially when combined with conventional therapeutics and Chinese medicinal herbal products.

  13. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy

    Directory of Open Access Journals (Sweden)

    Ming Hong

    2015-08-01

    Full Text Available In recent decades Chinese medicine has been used worldwide as a complementary and alternative medicine to treat cancer. Plenty of studies have shown that microRNAs (miRNAs play fundamental roles in many pathological processes, including cancer, while the anti-cancer mechanisms of Chinese medicinal herbs targeting miRNAs also have been extensively explored. Our previous studies and those of others on Chinese medicinal herbs and miRNAs in various cancer models have provided a possibility of new cancer therapies, for example, up-regulating the expression of miR-23a may activate the positive regulatory network of p53 and miR-23a involved in the mechanism underlying the anti-tumor effect of berberine in hepatocellular carcinoma (HCC. In this review, we survey the role of Chinese medicinal herbal products in regulating miRNAs in cancer and the use of mediating miRNAs for cancer treatment. In addition, the controversial roles of herb-derived exogenous miRNAs in cancer treatment are also discussed. It is expected that targeting miRNAs would provide a novel therapeutic approach in cancer therapy by improving overall response and survival outcomes in cancer treatment, especially when combined with conventional therapeutics and Chinese medicinal herbal products.

  14. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy

    International Nuclear Information System (INIS)

    In recent decades Chinese medicine has been used worldwide as a complementary and alternative medicine to treat cancer. Plenty of studies have shown that microRNAs (miRNAs) play fundamental roles in many pathological processes, including cancer, while the anti-cancer mechanisms of Chinese medicinal herbs targeting miRNAs also have been extensively explored. Our previous studies and those of others on Chinese medicinal herbs and miRNAs in various cancer models have provided a possibility of new cancer therapies, for example, up-regulating the expression of miR-23a may activate the positive regulatory network of p53 and miR-23a involved in the mechanism underlying the anti-tumor effect of berberine in hepatocellular carcinoma (HCC). In this review, we survey the role of Chinese medicinal herbal products in regulating miRNAs in cancer and the use of mediating miRNAs for cancer treatment. In addition, the controversial roles of herb-derived exogenous miRNAs in cancer treatment are also discussed. It is expected that targeting miRNAs would provide a novel therapeutic approach in cancer therapy by improving overall response and survival outcomes in cancer treatment, especially when combined with conventional therapeutics and Chinese medicinal herbal products

  15. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy.

    Science.gov (United States)

    Hong, Ming; Wang, Ning; Tan, Hor Yue; Tsao, Sai-Wah; Feng, Yibin

    2015-01-01

    In recent decades Chinese medicine has been used worldwide as a complementary and alternative medicine to treat cancer. Plenty of studies have shown that microRNAs (miRNAs) play fundamental roles in many pathological processes, including cancer, while the anti-cancer mechanisms of Chinese medicinal herbs targeting miRNAs also have been extensively explored. Our previous studies and those of others on Chinese medicinal herbs and miRNAs in various cancer models have provided a possibility of new cancer therapies, for example, up-regulating the expression of miR-23a may activate the positive regulatory network of p53 and miR-23a involved in the mechanism underlying the anti-tumor effect of berberine in hepatocellular carcinoma (HCC). In this review, we survey the role of Chinese medicinal herbal products in regulating miRNAs in cancer and the use of mediating miRNAs for cancer treatment. In addition, the controversial roles of herb-derived exogenous miRNAs in cancer treatment are also discussed. It is expected that targeting miRNAs would provide a novel therapeutic approach in cancer therapy by improving overall response and survival outcomes in cancer treatment, especially when combined with conventional therapeutics and Chinese medicinal herbal products. PMID:26305257

  16. Treatment of cholecystitis with Chinese herbal medicines: A systematic review of the literature

    Institute of Scientific and Technical Information of China (English)

    Zhi-Yong Dong; Guan-Liang Wang; Xing Liu; Jia Liu; De-Zeng Zhu; Chang-Quan Ling

    2012-01-01

    AIM:To analyze the literature on the use of Chinese herbal medicines for the treatment of cholecystitis.METHODS:The literature on treatment of cholecystitis with traditional Chinese medicines (TCM) was analyzed based on the principles and methods described by evidence-based medicine (EBM).Eight databases including MEDLINE,EMbase,Cochrane Central (CCTR),four Chinese databases (China Biological Medicine Database,Chinese National Knowledge Infrastructure Database,Database of Chinese Science and Technology Periodicals,Database of Chinese Ministry of Science and Technology) and Chinese Clinical Registry Center,were searched.Full text articles or abstracts concerning TCM treatment of cholecystitis were selected,categorized according to study design,the strength of evidence,the first author's hospital type,and analyzed statistically.RESULTS:A search of the literature published from 1977 through 2009 yielded 1468 articles in Chinese and 9 in other languages; and 93.92% of the articles focused on clinical studies.No article was of level I evidence,and 9.26% were of level Ⅱ evidence.The literature cited by Science Citation Index (SCI),MEDLINE and core Chinese medical journals accounted for 0.41%,0.68% and 7.29%,respectively.Typically,the articles featured in case reports of illness,examined from the perspective of EBM,were weak in both quality and evidence level,which inconsistently conflicted with the fact that most of the papers were by authors from Level-3 hospitals,the highest possible level evaluated based on their comprehensive quality and academic authenticity in China.CONCLUSION:The published literature on TCM treatment of cholecystitis is of low quality and based on low evidence,and cognitive medicine may functions as a useful supplementary framework for the evaluation.

  17. Chinese Petroleum Material and Equipment Export in 1996

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    @@ 1996 was a hard year for the export of Chinese machinery and electrical products, but it was an actual harvest one for exporting Chinese petroleum material, equipment and technology. The export value for CPTDC (China Petroleum Technology and Development Corporation) alone was close to $70 million, which was more than double as the previous year.

  18. Microwave—assisted Extraction of Effective Compounds from Traditional Chinese Herbal Medicine Ciwujia

    Institute of Scientific and Technical Information of China (English)

    王娟; 沈平孃; 沈永嘉

    2003-01-01

    Microwave-assisted extraction (MAE) fro active ingredients in Ciweujia was studied by using ethanol as the extractant.Comparing MAE with conventional methods,the former can save the extracting time and increase the content of the active ingredients in product,As to the operation in MAE ,the continuous radiation process is more convenient for the extraction for traditional Chinese medicine than the intermittent radiation process,Optimized by uniform design,MAE was proved to be an effective and novel process for extracting active ingredients in Ciwujia,The optimized MAE conditions are as follows:the microwave power is 510W,the radiation time 30 min the alohol concentration at 80%,the ratio of solvent to soild material being 5:1,the soaking time 0.5h ,and the herbal particle size is (520±19)μm.

  19. Typical Microstructures of Chinese Medicines with X-Ray Microscopy in Phase Contrast

    Institute of Scientific and Technical Information of China (English)

    WEI Xun; XIAO Ti-Qiao; LIU Li-Xiang; DU Guo-Hao; CHEN Min; LUO Yu-Yu; XU Hong-Jie

    2005-01-01

    @@ Due to the low absorption contrast of plant tissues, traditional x-ray radiography has not been included in the microscopic techniques used in the identification of traditional Chinese medicines (TCMs). With the development of x-ray phase contrast imaging (XPCI) in recent years, weakly absorbing materials could also be imaged by xrays. Here we investigate microstructures of TCMs utilizing XPCI based on a nano-focus x-ray tube. The results demonstrated that XPCI is capable of revealing the microstructures of TCMs used as judging criteria in the identification of TCMs. The major advantages of the new method are nondestructivity, no special demand for sample preparation and suitability for thick samples.

  20. Therapeutic uses of animal biles in traditional Chinese medicine: an ethnopharmacological, biophysical chemical and medicinal review.

    Science.gov (United States)

    Wang, David Q-H; Carey, Martin C

    2014-08-01

    Forty-four different animal biles obtained from both invertebrates and vertebrates (including human bile) have been used for centuries for a host of maladies in traditional Chinese medicine (TCM) beginning with dog, ox and common carp biles approximately in the Zhou dynasty (c. 1046-256 BCE). Overall, different animal biles were prescribed principally for the treatment of liver, biliary, skin (including burns), gynecological and heart diseases, as well as diseases of the eyes, ears, nose, mouth and throat. We present an informed opinion of the clinical efficacy of the medicinal uses of the different animal biles based on their presently known principal chemical components which are mostly steroidal detergent-like molecules and the membrane lipids such as unesterified cholesterol and mixed phosphatidylcholines and sometimes sphingomyelin, as well as containing lipopigments derived from heme principally bilirubin glucuronides. All of the available information on the ethnopharmacological uses of biles in TCM were collated from the rich collection of ancient Chinese books on materia medica held in libraries in China and United States and the composition of various animal biles was based on rigorous separatory and advanced chemical identification techniques published since the mid-20(th) century collected via library (Harvard's Countway Library) and electronic searches (PubMed and Google Scholar). Our analysis of ethnomedical data and information on biliary chemistry shows that specific bile salts, as well as the common bile pigment bilirubin and its glucuronides plus the minor components of bile such as vitamins A, D, E, K, as well as melatonin (N-acetyl-5-methoxytryptamine) are salutary in improving liver function, dissolving gallstones, inhibiting bacterial and viral multiplication, promoting cardiac chronotropsim, as well as exhibiting anti-inflammatory, anti-pyretic, anti-oxidant, sedative, anti-convulsive, anti-allergic, anti-congestive, anti-diabetic and anti

  1. [Construction of Research-Oriented State Key Clinical Department by Highlighting the Characteris- tics and Advantages of Chinese Medicine].

    Science.gov (United States)

    Ma, Shi-yu; Guo, Li-heng; Han, Yun; Li, Jian; Zhang, Min-zhou

    2016-04-01

    As the largest research-oriented specialty department in national traditional Chinese medicine hospitals, the Department of Critical Care Medicine in Guangdong Provincial Hospital of Chinese Medicine insists on the development mode combined with clinical medicine and scientific research. By taking clinical and basic researches for integrative medicine preventing and treating acute myocardial in-farction and sepsis as a breakthrough, authors explored key problems of Chinese medicine in improving the prognosis related diseases and patients' quality of life. In recent 3 years our department has successively become the principal unit of the national key specialties cooperative group of critical care medicine (awarded by State Administration of Traditional Chinese Medicine), the key clinical specialties (awarded by National Health and Family Planning Commission), and Guangzhou key laboratory construction unit, and achieved overall lap in clinical medical treatment, personnel training, scientific research, and social service.

  2. Studies on Treating Eczema by Chinese Herbal Medicine with Anti-Type Ⅳ Allergic Activity

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Objective: To study Chinese herbal prescription for treatment of eczema on the basis of the suppressive effect of Chinese herbal medicine with type Ⅳ allergic reaction. Methods: Various formulae composed of Chinese herbal medicines possessing suppressive effect on murine allergic contact dermatitis were formed following the therapeutic principles of traditional Chinese medicine in treating eczema, and their effect on ear swelling, ear flake weight, dermal inflammatory infiltration cell count and plasma level of calcitonin gene related peptide ( CGRP) were examined in mice with dinitrofluorobenzene induced dermatitis. The prescription, Composite Poria Decoction was formulated and made into granule form, which was used to treat 63 cases of eczema (atopic dermatitis was excluded), and compared with 59 cases treated with antihistaminic that was aimed at the type I allergic reaction. Results: Experimental study showed that all the 4 Chinese prescriptions had the effect of anti-type Ⅳ allergic reaction, among them, the formula for cooling blood and removing Heat, Wind and Dampness evil possessed the most potent effect in suppressing murine dermatitis, and it was also able to up-regulate the plasma CGRP concentration. The clinical cure rate of Composite Poria Granule treatment was 47.6%, and that of the control was 22.0%. The difference was significant between the two groups (u=2.9555, P<0.01). Conclusions: Chinese herbal medicine has the effect of anti-type Ⅳ allergic reaction. Composite Poria Granule has good effect in treating eczema.

  3. TREATMENT OF PRIMARY PALPEBRAL RETRACTION WITH ACUPOINT—INJECTION AND CHINESE MEDICINAL HERBS

    Institute of Scientific and Technical Information of China (English)

    朱新民; LiPeifang

    2000-01-01

    In the present paper,the therapeutic effect of combined therapy of acupoint-injection and Chinese medicinal herbs was observed in 59cases of primary palpebral retraction patients.These 59patients were divided into treatment group(n=38,treated with acupoint-injection and Chinese medicinal herbs)and control group(n=21,treated with Chinese medicinal herbs alone).After3 courses of treatment.of the 38cases in treatment group,25(65.8%)were cured,8(21.1%)had marked improement and5(13.2%)had improement;of the 21cases in control group,8(38.1%)were cured,9(42.9%)had marked improement,2(9.5%)had improement6 and2(9.5%)were ineffective.Statistical analysis showed a si9gnificant difference between the two groups in the therapeu-tic effect.The cure rate of experimental group was apparently higher than athat of the control group,i.e.the therapeutic effect of the combined therapy of acupoint-injection and Chinese medicinal herbs was superior to that of Chinese medicinal herbs alone.

  4. Traditional Chinese medicine valuably augments therapeutic options in the treatment of climacteric syndrome.

    Science.gov (United States)

    Eisenhardt, Sarah; Fleckenstein, Johannes

    2016-07-01

    Climacteric syndrome refers to recurring symptoms such as hot flashes, chills, headache, irritability and depression. This is usually experienced by menopausal women and can be related to a hormonal reorganization in the hypothalamic-pituitary-gonadal axis. In Traditional Chinese Medicine, originating 1000s of years ago, above-mentioned symptoms can be interpreted on the basis of the philosophic diagnostic concepts, such as the imbalance of Yin and Yang, the Zang-Fu and Basic substances (e.g. Qi, Blood and Essence). These concepts postulate balance and harmonization as the principle aim of a treatment. In this context, it is not astounding that one of the most prominent ancient textbooks dating back to 500-200 BC, Huang di Neijing: The Yellow Emperor's Classic of Internal Medicine gives already first instructions for diagnosis and therapy of climacteric symptoms. For therapy, traditional Chinese medicine comprises five treatment principles: Chinese herbal medicine, TuiNa (a Chinese form of manual therapy), nutrition, activity (e.g. QiGong) and acupuncture (being the most widespread form of treatment used in Europe). This review provides an easy access to the concepts of traditional Chinese medicine particularly regarding to climacteric syndrome and also focuses on current scientific evidence. PMID:27040419

  5. Screening of Chinese Herbal Medicines Resistant to Chicken Escherichia coli and Infectious Laryngotracheitis Virus

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    [Objective] This study aimed to screen Chinese herbal medicines resistant to Chicken Escherichia coli and infectious laryngotracheitis virus. [Methed] Conven- tional punch method, test tube method and plate dilution method were adopted for in vitro susceptibility test of chicken E, coil strains O5 and O8 using 13 kinds of Chi- nese herbal medicines including Sanguisorba officinalis, Coptis chinensis, Anemar- rhena asphodeloides, Strobilanthes cusia, Agastache rugosa, etc.; chicken embryo inoculation experiment was adopted to screen Chinese herbal medicines resistant to chicken infectious laryngotracheitis virus. [Result] Sanguisorba officinalis, Fructus mume, Rheum officinale, Coptis chinensis, Herba Taraxaci, Anemarrhena asphode- Ioides, Scutellaria baicalensis and Rhizoma Fagopyri Cymosi had ideal antibacterial effect against chicken E. coil strain O5; Sanguisorba officinalis, Fructus mume, Rheum officinale, Coptis chinensis, Herba taraxaci and Rhizoma Fagopyri Cymosi had ideal antibacterial effect against chicken E. coil strain 08; other Chinese herbal medicines showed relatively poor or no antibacterial effect. Results of chicken embryo inoculation experiment showed that nine kinds of Chinese herbal medicines showed relatively strong anti-lLTV effect, including Forsythia suspensa, Radix Isatidis, Fofium isatidis, Flos Ionicerae, Radix codonopsis, Radix astragali, Atractylodes, Radix gly- cyrrhizae, and Pericarpium granati. [Conclusion] The study laid the foundation for fur- ther development of Chinese herbal compound preparations to treat chicken cofibacil- Iosis, infectious laryngotracheitis and other bacterial, viral diseases.

  6. [Application characteristics and situation analysis of volatile oils in database of Chinese patent medicine].

    Science.gov (United States)

    Wang, Sai-Jun; Wu, Zhen-Feng; Yang, Ming; Wang, Ya-Qi; Hu, Peng-Yi; Jie, Xiao-Lu; Han, Fei; Wang, Fang

    2014-09-01

    Aromatic traditional Chinese medicines have a long history in China, with wide varieties. Volatile oils are active ingredients extracted from aromatic herbal medicines, which usually contain tens or hundreds of ingredients, with many biological activities. Therefore, volatile oils are often used in combined prescriptions and made into various efficient preparations for oral administration or external use. Based on the sources from the database of Newly Edited National Chinese Traditional Patent Medicines (the second edition), the author selected 266 Chinese patent medicines containing volatile oils in this paper, and then established an information sheet covering such items as name, dosage, dosage form, specification and usage, and main functions. Subsequently, on the basis of the multidisciplinary knowledge of pharmaceutics, traditional Chinese pharmacology and basic theory of traditional Chinese medicine, efforts were also made in the statistics of the dosage form and usage, variety of volatile oils and main functions, as well as the status analysis on volatile oils in terms of the dosage form development, prescription development, drug instruction and quality control, in order to lay a foundation for the further exploration of the market development situations of volatile oils and the future development orientation. PMID:25522633

  7. Effect of Chinese Medicines on the Subretinal Fluid Absorption after Operation for Retinal Detachment

    Institute of Scientific and Technical Information of China (English)

    YeziLiu

    1995-01-01

    Purpose:To determine the effects of traditional Chinese medicines on subretinal fluld absorption after Operation for retinal detachment.Mehods:Among100eyes with operations fo retinal detachment without drainage of fluid,there were 50eyes in traditional Chinese medicine treatment group and 50eyes in the control group.and there were no significant difference between the two groups in age,myopia and retinal detachment area.We observed the time for the absorption of subretinal fluid and visual acuity improvement aftr the opera-tions for retinal detachment.Results;he result showed that the average time for the absorption of subretinal fluid was14.5days in the traditional Chinese medicine treatment group,21.7days in the control group and the visual acuity was better in the former than in the latter.Conclusions:The taditional Chinese medicine treatment could increase the ab-sorption of subretional fluid,the mechanisms of which may be that Chinese medicines regulated and impved the general blood circulation and local eye blood criculation and the function of blood-retinal barrier so that they increase the out-ward osmotic suction forces of the pigment epithelium.

  8. 中药理论背后的隐性知识%The Tacit Knowledge Behind the Chinese Medicine Theory

    Institute of Scientific and Technical Information of China (English)

    步瑞兰

    2014-01-01

    历代本草著作均为博物之作,中药理论的形成与发展受多方面因素影响。传统文化中的鸟文化与禽类药物理论、饮食文化与滑类药物理论关系密切。药物在传统手工业、加工业及日常生活中的应用,同样影响到中药理论的形成与发展。文献学知识及实地采集辨识药物也是理解学习中药理论的基础。%The content of herbal works from each dynasty in ancient China is rich, broad and profound. the formation and development of TCM theory is influenced by various factors.Among the traditional culture,the bird culture have a close relationship with drugs of bird species and so is the Chinese Catering Culture with sliding drugs. The application of Chinese material medical in Traditional handicraft industry, processing industry and daily life has been played an important role during the formation and development of the Chinese medicine theory. Philological knowledge and field collection identification of drugs are also the foundation in understanding and learning Chinese medicine theory.

  9. Chinese medicine compound Changtong oral liquid on postoperative intestinal adhesions

    Institute of Scientific and Technical Information of China (English)

    Xi-Xiao Yang; Han-Ping Shi; Lian-Bing Hou

    2005-01-01

    AIM: The aim of this study was to observe the effect of a Chinese medicine compound Changtong oral liquid (CT) on tissue plasminogen activity (t-PA), plasminogen activator inhibitor (PAI), TGF-β1 and hydroxyproline (OHP).METHODS: Two sets of animal experiments were performed in the present study. Forty New Zealand rabbits and 48 Sprague-Dawley (SD) rats were assigned randomly to one of the five groups: sham adhesion, adhesion with saline, adhesion with low dosage of the CT, adhesion with middle dosage of the CT and adhesion with high dosage of the CT. t-PA and PAI activity in plasma, OHP and TGF-β1 expression in adhesion were investigated. Analysis of variance was used to test differences among groups.RESULTS: CT treatment increased plasma t-PA activity in rabbits but decreased TGF-β1 activity in rats. The data were expressed from low to high dose respectively as follows: t-PA, 46.1±8.6 μkat/L, 59.6±10.1 μkat/L, 64.0±11.5 μkat/L; TGF-β1 28±7.23%, 31±3.05%, 30±4.04%. There were significant differences compared with saline-treated animals (t-PA 26.4±5.1 μkat/L, TGF-β1 54±5.51%). OHP content in cecum of rabbits from middle and high but not low dose of CT lowered significantly as compared with saline-treated rabbits, 0.3641±0.1373, 0.3348±0.0321, 0.2757±0.0497 mg/g vs0.4183±0.0883 mg/g of protein, P>0.05, P<0.05, P<0.05 respectively. The rabbit plasma PAI activity and OHP content in abdominal wall had no difference in all groups.CONCLUSION: CT treatment significantly enhanced t-PA activity in rabbits, but decreased TGF-β1 content in rats, OHP content in cecum of rabbits, and failed to affect the activity of PAI and OHP content in abdominal wall in rabbits,compared with saline group. The result suggests that CT could effectively prevent adhesions without interfering wound healing.

  10. Source Book of Educational Materials for Nuclear Medicine.

    Science.gov (United States)

    Pijar, Mary Lou, Comp.; Lewis, Jeannine T., Comp.

    The contents of this sourcebook of educational materials are divided into the following sections: Anatomy and Physiology; Medical Terminology; Medical Ethics and Department Management; Patient Care and Medical Decision-Making; Basic Nuclear Medicine; Diagnostic in Vivo; Diagnostic in Vitro; Pediatric Nuclear Medicine; Radiation Detection and…

  11. Promoting integrative medicine by computerization of traditional Chinese medicine for scientific research and clinical practice: The SuiteTCM Project

    Institute of Scientific and Technical Information of China (English)

    Arthur de Sá Ferreira

    2013-01-01

    BACKGROUND:Chinese and contemporary Western medical practices evolved on different cultures and historical contexts and,therefore,their medical knowledge represents this cultural divergence.Computerization of traditional Chinese medicine (TCM) is being used to promote the integrative medicine to manage,process and integrate the knowledge related to TCM anatomy,physiology,semiology,pathophysiology,and therapy.METHODS:We proposed the development of the SuiteTCM software,a collection of integrated computational models mainly derived from epidemiology and statistical sciences for computerization of Chinese medicine scientific research and clinical practice in all levels of prevention.The software includes components for data management (DataTCM),simulation of cases (SimTCM),analyses and validation of datasets (SciTCM),clinical examination and pattern differentiation (DiagTCM,Tongue TCM,and Pulse TCM),intervention selection (AcuTCM,HerbsTCM,and DietTCM),management of medical records (ProntTCM),epidemiologic investigation of sampled data (ResearchTCM),and medical education,training,and assessment (StudentTCM).DISCUSSION:The SuiteTCM project is expected to contribute to the ongoing development of integrative medicine and the applicability of TCM in worldwide scientific research and health care.The SuiteTCM 1.0 runs on Windows XP or later and is freely available for download as an executable application.

  12. 基于熔解曲线分析技术的木通类药材的分子鉴别%HRM identification of Chinese medicinal materials Mutong

    Institute of Scientific and Technical Information of China (English)

    胡峻; 詹志来; 袁媛; 黄璐琦; 刘勇

    2015-01-01

    High resolution melting (HRM),an important technology for genotyping and mutation scanning,has broad prospects in the authentification of traditional Chinese medicine.This paper selected universal trnH-psbA primers and used HRM to establish a new methods for identification of Akebia herbs.PCR was conduct at the annealing temperature of 58 ℃ and 35 cycles.The range of the DNA template concentration,the primer concentration and the Mg2+ ion concentration were further analyzed.The results showed the Tm values of Caulis Akebiae was (81.84 ± 0.16),(85.28 ± 0.16) ℃ and Caulis Clematidis Armandii was (83.22 ± 0.19) ℃ and Caulis Aristolochiae manshuriensis was (81.67 ± 0.14) ℃,(84.24 ± 0.10) ℃ with 5-125 mg · L-1 DNA template,0.4 μmol · L-1 primer,2.0 mmol · L-1 Mg2+.This method can achieve the authentification of Akebia herbs and is simple,fast,high-throughput,visual.%高分辨率熔解曲线(high resolution melting,HRM)是一种主要用于基因分型和突变扫描的分子诊断技术,在中药真伪鉴定中有着广泛应用前景.该文将高分辨率熔解曲线技术应用于木通药材的鉴别,即选择trnH-psbA通用引物,在退火温度为58℃,35个循环数的条件下,建立正品木通药材的熔解曲线模型,并筛选确定其DNA模板浓度、引物浓度、Mg离子浓度的适宜范围.结果表明,在DNA质量浓度为5~125 mg·L-1、引物浓度0.4 μmol·L-1、Mg离子浓度2.0 mmol·L-1的条件下,木通药材的熔解曲线为双峰,其Tm为(81.84±0.16),(85.28 ±0.16)℃;川木通熔解曲线为单峰,其Tm为(83.22 ±0.19)℃;关木通熔解曲线为双峰,其Tm为(81.67±0.14),(84.24 ±0.10)℃.该方法可以实现简单、快速、高通量、可视化的的木通类药材的鉴定.

  13. 中药海尔福对老年痴呆症小鼠模型干预的实验研究%Research in Traditional Chinese Medicinal Materials Haier Fu on the Model Mice with Senile Dementia

    Institute of Scientific and Technical Information of China (English)

    何胜; 杨海龙; 吴艳; 蓝晓惠; 韦凤整; 张仲将; 黄春燕; 张树球

    2014-01-01

    OBJECTIVE: To study the effect of Haierfu and aluminum on the brain , enzymes, serum biochemical indexes and morphology in the model mice with Alzheimer ’ s disease ( AD ) . METHODS: The mice were fed with feed mixed by Aluminium chloride which lasted three consecutive months .The model mice with AD was establisted .After two months they were divided into three groups: treatment group 1, treatment group 2, model group and normal group .Using two different formulations of Haier Fu oral liquid of Chinese traditional medicine preparation cured treating group 1 and treatment group 2 for a month.Model group and normal group ware as control group which were fed by equal volume of distilled water instead of traditional Chinese Medicine Haier Fu .After the experiment 10%brain homogenate was made with the mice serum and brain .The activity of choline acetyl transferase ChAT , ace-tyl cholinesterase, AchE, aluminum content and the content of serum cholesterol were determined and the pathological examination of part of the brain was examied .RESULTS: In treatment group 1, group 2, the model group and normal group ChAT were respectively 86.70 ±16.26, 91.52 ±21.01, 29.73 ±10.25 and 9.51 ±24.17 (μ/g wet tissue) (P<0.01); O·2 MPA 27.12 ±2.68, 29.71 ±3.81 , 11.31 ±0.16 and 25.56 ±1.90 ( P<0.01 ); Serum cholesterol 3.35 ±0.34 , 2.83 ±0.41 , 4.11 ±0.25 and 3.10 ± 0.36 ( mmol/L) ( P<0.01 ) .All of them above compared with model group so that there were statistically significant difference . Compared with model group brain aluminum content respectively were 52.30 ±2.50 , 98.65 ±8.32 , 236.21 ±13.34 and 54.15 ± 2.80 (μg/L).There was statistically significant difference (P<0.05).Pathological examination result: in the normal control, the cerebral cortex and hippocampus neural cells , glial cells degeneration and necrosis , organization structure and the level did not signifi-cantly change; in model group , the cerebral cortex and hippocampus neural cells , glial

  14. Effect of Traditional Chinese Herbal Medicine with Antiquorum Sensing Activity on Pseudomonas aeruginosa

    Directory of Open Access Journals (Sweden)

    Weihua Chu

    2013-01-01

    Full Text Available Traditional Chinese herbal medicines (TCHMs were tested for their ability of antiquorum sensing. Water extracts of Rhubarb, Fructus gardeniae, and Andrographis paniculata show antiquorumsensing activity when using Chromobacterium violaceum CV12472 as reporter; the sub-MIC concentrations of these TCHMs were tested against AHL-dependent phenotypic expressions of PAO1. Results showed significant reduction in pyocyanin pigment, protease, elastase production, and biofilm formation in PAO1 without inhibiting the bacterial growth, revealing that the QSI by the extracts is not related to static or killing effects on the bacteria. The results indicate a potential modulation of bacterial cell-cell communication, P. aeruginosa biofilm, and virulence factors by traditional Chinese herbal medicine. This study introduces not only a new mode of action for traditional Chinese herbal medicines, but also a potential new therapeutic direction for the treatment of bacterial infections, which have QSI activity and might be important in reducing virulence and pathogenicity of pathogenic bacteria.

  15. Progress of Research in Treatment of Hyperlipidemia by Monomer or Compound Recipe of Chinese Herbal Medicine

    Institute of Scientific and Technical Information of China (English)

    DOU Xiao-bing; WO Xing-de; FAN Chun-lei

    2008-01-01

    Hyperlipidemia (HLP) is the No.1 risk factor for patients with atherosclerosis (AS) and is directly related to the occurrence of coronary artery disease (CAD) and cerebrovascular disease. Therefore, prevention and treatment of AS is of great importance and of practical significance in controlling the incidence and mortality of CAD. With its peculiar syndrome-dependent therapy, traditional Chinese medicine (TCM) has accumulated abundant practical experiences in this field and good clinical effects have been achieved. Chinese herbal medicine, with its particularly unique advantages and high potentials yet to be tapped, displays its huge strength in HLP prevention and treatment. The progress of studies concerning prevention and treatment of HLP by Chinese herbal medicines, in the form of monomers or compound recipes, is reviewed in this paper.

  16. The Impact of a Cultural Immersion Study Abroad Experience in Traditional Chinese Medicine.

    Science.gov (United States)

    Conroy, Shelley F; Taggart, Helen M

    2016-09-01

    Study abroad programs have increased dramatically. Most programs are short-term and include a cultural immersion as well as classroom and/or service learning. In this article, the authors discuss a study abroad program to China that included cultural immersion and classroom learning specific to traditional Chinese medicine. Participants kept journals with specific writing assignments and reflections about their experiences during the trip. At the conclusion of the trip, a qualitative survey was administered to the participants. Outcomes included the benefits of cultural immersion and a greater appreciation of cultural diversity, complementary and alternative medicine and holistic health care. Participants were able to describe transformational experiences of living in and learning from the Chinese culture and peoples. They intended to incorporate their experiences and enhanced understanding of traditional Chinese medicine and complementary and alternative therapies to provide culturally competent holistic health care in their nursing practice. PMID:26351293

  17. Mining Compatibility Rules from Irregular Chinese Traditional Medicine Database by Apriori Agorithm

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    This paper aims to mine the knowledge and rules on compatibility of drugs from the prescriptions for curing arrhythmia in the Chinese traditional medicine database by Apriori algorithm. For data preparation, 1 113 prescriptions for arrhythmia, including 535herbs (totally 10884 counts of herbs) were collected into the database. The prescription data were preprocessed through redundancy reduction, normalized storage, and knowledge induction according to the pretreatment demands of data mining. Then the Apriori algorithm was used to analyze the data and form the related technical rules and treatment procedures. The experimental result of compatibility of drugs for curing arrhythmia from the Chinese traditional medicine database shows that the prescription compatibility obtained by Apriori algorithm generally accords with the basic law of traditional Chinese medicine for arrhythmia. Some special compatibilities unreported were also discovered in the experiment, which may be used as the basis for developing new prescriptions for arrhythmia.

  18. Acupuncture plus Chinese Medicinal Fumigation and Washing for Edema of the Stroke-affected Limb

    Institute of Scientific and Technical Information of China (English)

    Wu Bin

    2014-01-01

    Objective: To evaluate the therapeutic efficacy of acupuncture plus Chinese medicinal fumigation and washing in treating edema of the affected limb in post-stroke hemiplegia. Methods: Two hundred patients with edema of the stroke-affected limb from our hospital were randomized into two groups according to their visiting sequence. In the observation group, 100 subjects were intervened by acupuncture plus Chinese medicinal fumigation and washing in addition to oral administration of diuretics, while the other 100 subjects in the control group were only given diuretics. The therapeutic efficacy was evaluated after successive 2-week treatments. Results: The total effective rate was 90.0% in the observation group, significantly higher than 66.0% in the control group, indicating that there was a significant difference in comparing the overall therapeutic effect (P Conclusion: Acupuncture plus Chinese medicinal fumigation and washing in addition to oral administration of diuretics is effective in treating edema of the affected limb in post-stroke hemiplegia.

  19. Roles of Chinese herbal medicines in ischemic heart diseases (IHD) by regulating oxidative stress.

    Science.gov (United States)

    Wang, Dawei; Wang, Jin; Liu, Yuntao; Zhao, Zhen; Liu, Qing

    2016-10-01

    Ischemic heart disease (IHD) basing on atherosclerosis (AS) is known as a top killer for decades. Oxidative stress, representing excessive oxidation and insufficient elimination, has been proved to be a critical molecular mechanism of IHD and accompanying myocardium dysfunction. Therefore, anti-oxidation therapy may be efficient. Chinese herbal medicine, including extractive compounds, decoctions, patent drugs, and injections, has shown its enormous potential in prevention and treatment of IHD as an effective antioxidant in experimental studies. The aim of this review is to highlight recent studies of Chinese herbal medicine in regulating oxidative stress in IHD. These studies represent recent progress of IHD treatment and indicate the possible pathways and target spots of Chinese herbal medicine. PMID:27390948

  20. [A brief history of Chinese royal court medicines].

    Science.gov (United States)

    Li, Chun-Sheng

    2010-09-01

    With the establishment of an emperor and a royal court, the court physician came into being and the royal court medicines gradually began to evolve. In the first year of Kai Huang of the Sui dynasty (581), King Wendi of the Sui dynasty established the imperial medical bureau. Since then the royal court medicines entered a period of development and prosperity. In the Yuan dynasty, the scope of official duty of the imperial hospital narrowed, the development of royal court medicines lacked new growth. To the Ming and Qing dynasties, the royal court medicine began to decline and eventually ended with the demise of the Qing dynasty. PMID:21163077

  1. [Controllability pyramid: an integrated control system of quality for traditional Chinese medicines].

    Science.gov (United States)

    Xiao, Xiao-He; Zhang, Ding-Kun; Wang, Jia-Bo; Yang, Ming; Peng, Cheng

    2015-01-01

    Quality control is one of the key scientific tissues in the modernization of traditional Chinese medicines (TCM). In order to overcome the deficiencies of assessment indexes, including little systematization and quantification, as well as loose association with clinical efficacy and dosage, a new integrated method named controllability pyramid ( CP) is first proposed in this paper. In addition, some study cases are used to explain how this model is constructed. We hope the establishment of CP could promote the clinical-orien- ted integrated innovation research of TCM, and provide control strategy and technology examples for improving the quality of Chinese medicines and clinical efficacy.

  2. Clinical Study on Treatment of Hyperuricaemia by Retention Enema of Chinese Herbal Medicine Combined with Allopurinol

    Institute of Scientific and Technical Information of China (English)

    陈茜; 马丽; 阿克拜尔·乌普

    2009-01-01

    Objective:To study the effect of retention enema of Chinese herbal medicine combined with allopurinol in treating hyperuricaemia(HUE).Methods:Seventy-eight patients with HUE were assigned to two groups,the 40 patients in the treated group were treated with retention enema of Chinese herbal medicine combined with oral intake of allopurinol,and the 38 patients in the control group were treated with allopurinol alone. The therapeutic course for all was 6 weeks.The clinical efficacy,changes of symptoms,blood...

  3. [Changes of career of traditional Chinese medicine in Hong Kong Donghua Hospital in modern times].

    Science.gov (United States)

    Zheng, H

    2016-05-01

    Founded in 1872, the Hong Kong Donghua Hospital (Tung Wah Group of Hospitals later) was the earliest traditional Chinese hospital in modern times, which has made positive contributions in exploring the shape and structure of TCM hospital and promoting science of TCM in Hong Kong. Unfortunately, TCM didn't acquire a legal status in Hong Kong, the practice of TCM in Donghua Hospital was thus restricted by the government, and ultimately, it changed into a comprehensive hospital mainly use western medicine. The change of TCM business in Hong Kong Donghua Hospital reflected the problems and situation of traditional Chinese medicine encountered in modern times. PMID:27485869

  4. Application of Systems Biology Technology in Research of Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    LI Ping; YANG Li-ping; GONG Yue-wen

    2009-01-01

    Systems biology is an emerging science of the 21 st century and its method and design of study resemble those of traditional Chinese medicine (TCM). Adopting systems biology technology will help to understand TCM Syndromes and modernize Chinese herbal medicine. The technology platforms of systems biology,especially proteomics can provide useful tools for exploring essence of TCM syndromes and understanding principle of herbal formulation. Moreover, compared with methods of molecular biology, such as genomics and proteomics, metabolomics provide more direct, rapid, concise and effective methods for study of kidney disease especiallv in the case of prevention and treatment with TCM.

  5. Research advances on the anti-aging profile of Fructus lycii: An ancient Chinese herbal medicine

    OpenAIRE

    Sze, SCW; Chang, RCC; Zhang, KY; Tong, Y; Song, J.; Wong, RNS

    2008-01-01

    Fructus lycii is a common Chinese herbal medicine used in China for nearly 2000 years. It has beneficial effects on eyes, liver and kidneys; and it has long been considered to be an anti-aging herb in ancient Chinese medicine. Modern studies have partially probed the magic anti-aging property of F. lycii. The beneficial effects of F. lycii on aging are largely attributed to its bioactive components such as polysaccharides, carotenoids and flavonoids. This review focuses on the anti-aging aspe...

  6. Several considerations in using traditional Chinese patent medicine for cerebral infarction.

    Science.gov (United States)

    He, Jia; Kwon, Yihyun; Li, Chao; Zhang, Xue-Qi; Zhao, Jian-Guo

    2012-08-01

    Nowadays, a great number of traditional Chinese patent medicine (TCPM) are used more and more widely to treat cerebral infarction in China. When great attention is paid to using TCPM in the real world, several problems can be identified: ignoring the Chinese medicine (CM) therapeutic principle based on syndrome differentiation, a lack of appropriate dosage and usage based on individual patient conditions, and a shortage of evidence from randomized, double-blind, placebo-controlled clinical trials. Furthermore, in terms of evaluation of the TCPM effectiveness, few comprehensive criteria and evaluation methods recognized by the international community exist. This article addresses some opinions regarding the above mentioned problems. PMID:22855032

  7. [Strategy and core technologies for the secondary development of Chinese patent medicine].

    Science.gov (United States)

    Zhagn, Bo-Li; Fan, Xiao-Hui; Liu, Yang; Qu, Hai-Bin; Zhang, Jun-Hua; Chegn, Yi-Yu

    2013-11-01

    Secondary development of Chinese Patent Medicine (CPM) is an effective and innovation-driven way for the leaping development of Chinese medicine industry with less investment and faster return. Aim to improving the efficacy, safety and batch-to-batch consistency of CPMs, the theory and methodology for the secondary development of CPMs, mode for cultivating superior CPM, approaches to reforming the pharmaceutical technology and the corresponding core technologies were proposed in this paper, which is summarized as 'One objective, Three analyses, Five definitudes and Seven improvements'. PMID:24558853

  8. The carbon isotope ratios and contents of mineral elements in leaves of Chinese medicinal plants

    International Nuclear Information System (INIS)

    Leaf carbon isotope ratios and 13 kinds of mineral elements were measured on 36 species of common Chinese medicinal plants in a subtropical monsoon forest of Ding Hu Shan in Guangdong Province. The .delta.13C value were from -26.4 to -32.6%, indicating that all of the species belonged the photosynthetic C3 types. The relative lower value of δ13C was observed in the life form of shrubs. The contents of 7 elements (N, P, K, Ca, Na Mg, Si) were dependent upon the species, life form, medicinal function and medicinal part. Herb type medicine and the used medicinal part of leaves or whole plant showed higher levels of above elements than the others. Among the nine groups with different medicinal functions, it was found that more nitrogen was in the leaves of medicinal plants for hemophthisis, hypertension and stomachic troubles, more phosphorus and potassium were in the leaves for cancer and snake bite medicines, but more calcium and magnesium were in the leaves for curing rheumatics. Ferric, aluminium and manganese were the main composition of microelements in leaves. There were higher content of ferric in leaves for hemophthisis medicine, higher zinc in leaves for cold and hypertension medicine, and higher Cup in leaves of stomachic medicine. It was suggested that the pattern of mineral elements in leaves of Chinese medicinal plants reflected the different properties of absorption and accumulation. Some additional effect due to the high content of certain element might be associated with the main function of that medicine

  9. Treatment of 140 cerebral palsied children with a combined method based on traditional Chinese medicine (TCM) and western medicine

    Institute of Scientific and Technical Information of China (English)

    ZHOU Xue-juan; ZHENG Kun

    2005-01-01

    Objective: To observe and evaluate a method that is effective and practical for treatment of cerebral palsied (CP)children in China. Method: The patient's age and disease type and individual specific conditions were considered in choosing therapy methods accordingly: Chinese herbs, acupuncture, auricular seed pressure, point finger pressing, massage, orthopedic hand manipulation, physiotherapy, occupational therapy, language therapy, etc. Meanwhile we created a new CP treatment model that combines hospitalized treatment with family therapy. Results: The majority of CP patients improved greatly in motor and social adaptation capacities after treatment. Wilcoxon paired rank sum test analysis showed that there were significant differences between the data before and after treatment (P<0.01). Conclusion: This combined therapy method, based on traditional Chinese medicine and western medicine plus family supplemental therapy, is an effective and practical treatment strategy for CP children in China.

  10. Synergistic effects of Chinese herbal medicine: a comprehensive review of methodology and current research

    Directory of Open Access Journals (Sweden)

    Xian Zhou

    2016-07-01

    Full Text Available Traditional Chinese medicine is an important part of primary health care in Asian countries that has utilised complex herbal formulations (consisting 2 or more medicinal herbs for treating diseases over thousands of years. There seems to be a general assumption that the synergistic therapeutic effects of Chinese herbal medicine derive from the complex interactions between the multiple bioactive components within the herbs and/or herbal formulations. However, evidence to support these synergistic effects remains weak and controversial due to several reasons, including the very complex nature of Chinese herbal medicine, misconceptions about synergy, methodological challenges to study design. In this review, we clarify the definition of synergy, identify common errors in synergy research and describe current methodological approaches to test for synergistic interaction. We discuss the strengthen and weakness of these models in the context of Chinese herbal medicine and summarise the current status of synergy research in CHM. Despite the availability of some scientific data to support the synergistic effects of multi-herbal and/or herb-drug combinations, the level of evidence remains low and the clinical relevancy of most of these findings is undetermined. There remain significant challenges in the development of suitable methods for synergistic studies of complex herbal combinations.

  11. Current Status and Future Perspective in the Globalization of Traditional Chinese Medicines

    Directory of Open Access Journals (Sweden)

    Wan-Ying Wu

    2015-01-01

    Full Text Available Globalization of traditional Chinese medicines started around 1996, which was initiated by the Chinese government. However, substantial progress was only achieved in recent years including the adoption of TCM quality monographs in the western pharmacopoeias (United States Pharmacopoeia and European Pharmacopoeia and registration in main stream drug regulatory agencies such as US Food and Drug Administration (FDA and European Medicines Agency (EMA. So far, several TCM herbal quality monographs were adopted by the United States Pharmacopoeia including Chinese Salvia, Ganoderma lucidum and Panax notoginseng, etc. Over 45 TCM quality monographs were recorded in the European Pharmacopoeia with 20 more in progress. After the successful registration of the first TCM product named Diao Xin Xue Kang as traditional medicine via the Medicines Evaluation Board of the Netherlands, several other TCM herbal products are in the registration process in several European member states. So far, there has been still not any TCM product authorized as a drug by the FDA regardless of a few TCM products in phase III or phase II clinical trials. This review summarizes the progress made in the globalization of traditional Chinese medicines in recent years and future issues in this regard.

  12. Sustainable Utilization of Traditional Chinese Medicine Resources: Systematic Evaluation on Different Production Modes

    Directory of Open Access Journals (Sweden)

    Xiwen Li

    2015-01-01

    Full Text Available The usage amount of medicinal plant rapidly increased along with the development of traditional Chinese medicine industry. The higher market demand and the shortage of wild herbal resources enforce us to carry out large-scale introduction and cultivation. Herbal cultivation can ease current contradiction between medicinal resources supply and demand while they bring new problems such as pesticide residues and plant disease and pests. Researchers have recently placed high hopes on the application of natural fostering, a new method incorporated herbal production and diversity protecting practically, which can solve the problems brought by artificial cultivation. However no modes can solve all problems existing in current herbal production. This study evaluated different production modes including cultivation, natural fostering, and wild collection to guide the traditional Chinese medicine production for sustainable utilization of herbal resources.

  13. Herbal traditional Chinese medicine and its evidence base in gastrointestinal disorders

    OpenAIRE

    Teschke, Rolf; Wolff, Albrecht; Frenzel, Christian; Eickhoff, Axel; Schulze, Johannes

    2015-01-01

    Herbal traditional Chinese medicine (TCM) is used to treat several ailments, but its efficiency is poorly documented and hence debated, as opposed to modern medicine commonly providing effective therapies. The aim of this review article is to present a practical reference guide on the role of herbal TCM in managing gastrointestinal disorders, supported by systematic reviews and evidence based trials. A literature search using herbal TCM combined with terms for gastrointestinal disorders in Pu...

  14. Qualitative and Quantitative Analysis for Facial Complexion in Traditional Chinese Medicine

    OpenAIRE

    Changbo Zhao; Guo-zheng Li; Fufeng Li; Zhi Wang; Chang Liu

    2014-01-01

    Facial diagnosis is an important and very intuitive diagnostic method in Traditional Chinese Medicine (TCM). However, due to its qualitative and experience-based subjective property, traditional facial diagnosis has a certain limitation in clinical medicine. The computerized inspection method provides classification models to recognize facial complexion (including color and gloss). However, the previous works only study the classification problems of facial complexion, which is considered as ...

  15. Review on the course of Chinese medicine regulation in the UK of the last 10 years.

    OpenAIRE

    Cheng, Ming Zhao; Shen, Huijun

    2010-01-01

    This article reviews the course of work in the last ten years of developing a system of statutory regulation of practitioners of acupuncture, herbal medicine and Traditional Chinese Medicine. It tracks from the House of Lords Science Select Committee report on complementary medcine in 2000 till the recent 2nd Department of Health's consultation on the regulation of these professionals. It would be very interesting to see what decision of the DH is to make on regualtion of these pratitioners.

  16. Chinese Herbal Medicine in Folk Custom%民俗中的中草药略识

    Institute of Scientific and Technical Information of China (English)

    齐敏; 李春芳

    2009-01-01

    There are large amount of Chinese herbal medicine used in folk custom of our country. Most of these medicines are related with hygiene and health care. The usage of these medicine included avoiding dirty, preventing diseases, restoring convalescence, health protection, cosmetology, bathing, and daily effective medical prescription. Folk custom has the characteristics of regionality, consistency, and nationality,ete. Some of traditional Chinese medicine originates from folk custom. Therefore, the research of medicine used in folk custom may help to the development of traditional Chinese medicine.%在我国传统民俗中流传有大量中草药,其用途主要包括辟秽防病、康复保健、美容化妆、服饰佩物、洗浴、日常疗病等.民俗为群体性、倾向性的社会行为,并有地域性、传承性、历史性、民族性等特点,同时中草药中的一部分药物也来源于民俗,研究民俗中的药物可有助于研发中药新药.

  17. Utilization of and Attitudes towards Traditional Chinese Medicine Therapies in a Chinese Cancer Hospital: A Survey of Patients and Physicians

    OpenAIRE

    McQuade, Jennifer L.; ZhiQiang Meng; Zhen Chen; Qi Wei; Ying Zhang; WenYing Bei; J. Lynn Palmer; Lorenzo Cohen

    2012-01-01

    Background. In China, the use of traditional Chinese medicine (TCM) is very popular, but little is known about how it is integrated with conventional cancer care. We conducted parallel surveys of patients and physicians on TCM utilization. Methods. Two hundred forty-five patients and 72 allopathic physicians at the Fudan University Shanghai Cancer Center completed questions on their use of and attitude towards TCM. Results. Patient mean age was 51, with 60% female. Eighty-three percent of pa...

  18. Use of radioactive materials in Medicine

    International Nuclear Information System (INIS)

    The diagnostic studies of Molecular Nuclear Medicine allow diagnose, to confirm and characterize a large variety of illnesses avoiding at the same time the cost and or the risk or other studies for confirming or excluding the illness, providing new information which can characterize more accurately the syndrome which would be present the patient. The new information is reliable since it can be reproduced and with this to make a follow-up adequate of the person. The new and trusty information obtained allows to increase or diminish quickly the probability which the patient had a specific illness. (Author)

  19. 我院门诊中药处方分析%Analysis Of Prescriptions Of Traditional Chinese Medicines in our Hospital

    Institute of Scientific and Technical Information of China (English)

    黄培艳

    2011-01-01

    Objective To analyze the utilization of traditional Chinese medicines in outpatient prescription of our hospital to offer guidance for pharmacy work and provide reference for rational use of traditional Chinese medicines in clinic. Methods The systematic analysis of the outpatient prescriptions of traditional Chinese medicines in 2009 was performed. Results Of checked 1 555 prescriptions, 112 prescriptions were unqualified, accounting for 7. 20%. The Chinese medicinal materials involved in the prescriptions were 313 varieties. The usual drugs were mainly tonifying deficiency medicines. Conclusion The prescription writing in our hospital is basically qualified. Clinical doctors should enhance their own professional skills and reduce the irrational prescriptions as possible.%目的 了解医院门诊中药处方用药状况,为中药房工作和中医临床用药提供参考.方法 对2009年门诊中药处方进行系统分析.结果 调查门诊处方共1555张,其中不合格处方112张,占处方总数的7.20%;处方涉及中药材313种,常用药物以补虚药为主.结论 处方书写基本合格,医生应加强专业知识学习尽量减少不合理处方.

  20. Data-mining of potential antitubercular activities from molecular ingredients of traditional Chinese medicines

    Directory of Open Access Journals (Sweden)

    Salma Jamal

    2014-07-01

    Full Text Available Background. Traditional Chinese medicine encompasses a well established alternate system of medicine based on a broad range of herbal formulations and is practiced extensively in the region for the treatment of a wide variety of diseases. In recent years, several reports describe in depth studies of the molecular ingredients of traditional Chinese medicines on the biological activities including anti-bacterial activities. The availability of a well-curated dataset of molecular ingredients of traditional Chinese medicines and accurate in-silico cheminformatics models for data mining for antitubercular agents and computational filters to prioritize molecules has prompted us to search for potential hits from these datasets. Results. We used a consensus approach to predict molecules with potential antitubercular activities from a large dataset of molecular ingredients of traditional Chinese medicines available in the public domain. We further prioritized 160 molecules based on five computational filters (SMARTSfilter so as to avoid potentially undesirable molecules. We further examined the molecules for permeability across Mycobacterial cell wall and for potential activities against non-replicating and drug tolerant Mycobacteria. Additional in-depth literature surveys for the reported antitubercular activities of the molecular ingredients and their sources were considered for drawing support to prioritization. Conclusions. Our analysis suggests that datasets of molecular ingredients of traditional Chinese medicines offer a new opportunity to mine for potential biological activities. In this report, we suggest a proof-of-concept methodology to prioritize molecules for further experimental assays using a variety of computational tools. We also additionally suggest that a subset of prioritized molecules could be used for evaluation for tuberculosis due to their additional effect against non-replicating tuberculosis as well as the additional hepato

  1. French City Calais Shows Great Appetite for Chinese Stone Materials

    Institute of Scientific and Technical Information of China (English)

    Xu Hao

    2005-01-01

    @@ A French government delegation headed by the President of the Municipal Planning & Design Bureau of Calais City and Mr. Han Guogang, President of France China International Development Institution investigated Chinese stone materials market during April 28 to April 29, they showed great interest in some stone materials in good quality such as "China Black".

  2. Innovative Strategy in Treating Angina Pectoris with Chinese Patent Medicines by Promoting Blood Circulation and Removing Blood Stasis: Experience from Combination Therapy in Chinese Medicine.

    Science.gov (United States)

    Xiong, Xing-Jiang; Wang, Zhong; Wang, Jie

    2015-01-01

    Coronary heart disease (CHD) is one of the leading causes of death worldwide. Moreover, angina pectoris is one of the most important types of CHD. Therefore, prevention and effective treatment of angina pectoris is of utmost importance in both China and western countries. However, undesirable effects of antianginal therapy do influence treatment adherence to a certain extent. Therefore, it's not surprising that, complementary and alternative medicine (CAM), including Chinese medicine (CM), are widely welcomed among patients with CHD, hoping that it might complement western medicine. In our previous studies, blood stasis syndrome (BSS) (Xueyu Zheng) was the main syndrome (Zheng-hou) of angina pectoris. Currently, China Food and Drug Administration authoritatively recommended more than 200 Chinese patent medicines (CPMs) as complementary or adjunctive therapies for symptom management and enhancing quality of life along with mainstream care on angina pectoris management in mainland China. This paper reviewed 4 kinds of most frequently-used CPMs by promoting blood circulation and removing blood stasis in the treatment of angina pectoris. It aims to evaluate the current evidence of CPMs in combination therapy for angina pectoris. This review indicated that CPMs as adjunctive treatment to routine antianginal therapy play an active role in reducing the incidence of primary endpoint events, decreasing anginal attack rate, and improving electrocardiogram. Additionally, CPMs have been proven relatively safe. Further rigorously designed clinical trials should be conducted to confirm the results. PMID:25360837

  3. 芪白平肺胶囊药材挥发油β-环糊精包合物的制备及其表征%Preparation and Characterization of β-cyclodextrin Inclusion Compound of Volatile Oils from Traditional Chinese Medicinal Materials in Qibai Pingfei Capsules

    Institute of Scientific and Technical Information of China (English)

    陈娟; 李泽庚; 孟楣; 韩燕全; 高家荣

    2011-01-01

    Objective To prepare β-cyclodextrin (β-CD) inclusion compound of volatile oils from traditional Chinese medicinal materials in Qibai Pingfei Capsules, and to identify its characterization. Methods An orthogonal design was carried out to optimize the preparation of β-CD inclusion compound of volatile oils from traditional Chinese medicinal materials in Qibai Pingfei Capsules. The inclusion compound was identified by thin layer chromatography, differential scanning calorimetry, and X-ray powder diffractometry.Results The optimum conditions were obtained as follows: the ratio of oils to β-CD was 1:8(ml/g) , the temperature of inclusion was 50℃, the inclusion time was 2 h. The main compositions of volatile oils in the inclusion compound did not change significantly. The difference between the inclusion and physical mixtures in the curve was significant. Conclusion The optimized process is simple and reasonable. A stable inclusion compound of volatile oils and β-CD is formed.%目的 制备芪白平肺胶囊药材挥发油-β-环糊精(β-cyclodextrin, β-CD)包合物,并考察其表征.方法 采用正交试验法,优选芪白平肺胶囊药材中挥发油-β-CD包合物的制备工艺,采用薄层色谱法、差示扫描量热法、X射线粉末衍射法对包合物进行物相鉴定.结果 最佳包合工艺为:挥发油与β-CD的投料比为1∶8(ml/g),温度为50 ℃,包合时间为2 h.混合挥发油包合后,成分未见明显改变,包合物与β-CD物理混合物的图谱有显著性差异.结论 优选的包合工艺合理、简便易行,挥发油与β-CD形成稳定的包合物.

  4. Chinese Herbal Medicine Image Recognition and Retrieval by Convolutional Neural Network.

    Science.gov (United States)

    Sun, Xin; Qian, Huinan

    2016-01-01

    Chinese herbal medicine image recognition and retrieval have great potential of practical applications. Several previous studies have focused on the recognition with hand-crafted image features, but there are two limitations in them. Firstly, most of these hand-crafted features are low-level image representation, which is easily affected by noise and background. Secondly, the medicine images are very clean without any backgrounds, which makes it difficult to use in practical applications. Therefore, designing high-level image representation for recognition and retrieval in real world medicine images is facing a great challenge. Inspired by the recent progress of deep learning in computer vision, we realize that deep learning methods may provide robust medicine image representation. In this paper, we propose to use the Convolutional Neural Network (CNN) for Chinese herbal medicine image recognition and retrieval. For the recognition problem, we use the softmax loss to optimize the recognition network; then for the retrieval problem, we fine-tune the recognition network by adding a triplet loss to search for the most similar medicine images. To evaluate our method, we construct a public database of herbal medicine images with cluttered backgrounds, which has in total 5523 images with 95 popular Chinese medicine categories. Experimental results show that our method can achieve the average recognition precision of 71% and the average retrieval precision of 53% over all the 95 medicine categories, which are quite promising given the fact that the real world images have multiple pieces of occluded herbal and cluttered backgrounds. Besides, our proposed method achieves the state-of-the-art performance by improving previous studies with a large margin.

  5. Chinese Herbal Medicine Image Recognition and Retrieval by Convolutional Neural Network.

    Directory of Open Access Journals (Sweden)

    Xin Sun

    Full Text Available Chinese herbal medicine image recognition and retrieval have great potential of practical applications. Several previous studies have focused on the recognition with hand-crafted image features, but there are two limitations in them. Firstly, most of these hand-crafted features are low-level image representation, which is easily affected by noise and background. Secondly, the medicine images are very clean without any backgrounds, which makes it difficult to use in practical applications. Therefore, designing high-level image representation for recognition and retrieval in real world medicine images is facing a great challenge. Inspired by the recent progress of deep learning in computer vision, we realize that deep learning methods may provide robust medicine image representation. In this paper, we propose to use the Convolutional Neural Network (CNN for Chinese herbal medicine image recognition and retrieval. For the recognition problem, we use the softmax loss to optimize the recognition network; then for the retrieval problem, we fine-tune the recognition network by adding a triplet loss to search for the most similar medicine images. To evaluate our method, we construct a public database of herbal medicine images with cluttered backgrounds, which has in total 5523 images with 95 popular Chinese medicine categories. Experimental results show that our method can achieve the average recognition precision of 71% and the average retrieval precision of 53% over all the 95 medicine categories, which are quite promising given the fact that the real world images have multiple pieces of occluded herbal and cluttered backgrounds. Besides, our proposed method achieves the state-of-the-art performance by improving previous studies with a large margin.

  6. Chinese Herbal Medicine Image Recognition and Retrieval by Convolutional Neural Network.

    Science.gov (United States)

    Sun, Xin; Qian, Huinan

    2016-01-01

    Chinese herbal medicine image recognition and retrieval have great potential of practical applications. Several previous studies have focused on the recognition with hand-crafted image features, but there are two limitations in them. Firstly, most of these hand-crafted features are low-level image representation, which is easily affected by noise and background. Secondly, the medicine images are very clean without any backgrounds, which makes it difficult to use in practical applications. Therefore, designing high-level image representation for recognition and retrieval in real world medicine images is facing a great challenge. Inspired by the recent progress of deep learning in computer vision, we realize that deep learning methods may provide robust medicine image representation. In this paper, we propose to use the Convolutional Neural Network (CNN) for Chinese herbal medicine image recognition and retrieval. For the recognition problem, we use the softmax loss to optimize the recognition network; then for the retrieval problem, we fine-tune the recognition network by adding a triplet loss to search for the most similar medicine images. To evaluate our method, we construct a public database of herbal medicine images with cluttered backgrounds, which has in total 5523 images with 95 popular Chinese medicine categories. Experimental results show that our method can achieve the average recognition precision of 71% and the average retrieval precision of 53% over all the 95 medicine categories, which are quite promising given the fact that the real world images have multiple pieces of occluded herbal and cluttered backgrounds. Besides, our proposed method achieves the state-of-the-art performance by improving previous studies with a large margin. PMID:27258404

  7. Integrated Development of Chinese Herbal Medicine Planting and Tourist Commodities: A Case Study of Green Handmade Soap Development in Shandong Province

    Institute of Scientific and Technical Information of China (English)

    Xiu; LI; Mengxuan; CHEN; Xiaoli; SONG

    2015-01-01

    Combining current situations of Chinese herbal medicine planting industry in Shandong,in line with existing problems of Chinese herbal medicine planting industry,this paper analyzed development prospect of tourist commodity industry in Shandong Province,and came up with actual selection and recommendations for integrated development of Chinese herbal medicine planting and tourist commodities.

  8. Evaluation on Common Hand, Foot and Mouth Disease Treated by Integrative Traditional Chinese Medicine and Western Medicine

    Institute of Scientific and Technical Information of China (English)

    Guo-liang Zhang; Qing-xiong Zhu; Tong Yang; Zi-qiang Zhuo; Yi-mei Tian; Hao-jie Zheng; Liu-ping Tang; Xin-ying Zou; Tao Wen; Xiu-hui Li; Jian-bo Ding; Shuang-jie Li; Xi Zhang; Yi Xu; Hua-sheng Yang; Dan Wei; Qin Li; Qing-sheng Shi

    2013-01-01

    Objective To evaluate the efifcacy and safety of traditional Chinese medicine (TCM) combined with Western medicine in the treatment of patients with common hand, foot and mouth disease (HFMD) by conducting a prospective, controlled, and randomized trial. Methods A total of 452 patients with common HFMD were randomly assigned to receive Western medicine alone (n=220) or combined with TCM (Reduning or Xiyanping injections) (n=232). The primary outcome was the incidence rate of rash/herpes disappearance within 5 days, while secondary outcomes included the incidence rate for fever, cough, lethargy, agitation, and vomiting clearance within 5 days. Results The rash/herpes disappearance rate was 45.5% (100/220) in Western medicine therapy group, and 67.2% (156/232) in TCM and Western medicine combined therapy group, with significant difference (P Conclusions It’s suggested that the integrative TCM and Western medicine therapy achieved a better therapeutic efficacy. TCM may become an important complementary therapy on relieving the symptoms of HFMD.

  9. [A comparative study on the ethics of Western and traditional Chinese medicine].

    Science.gov (United States)

    Zhang, Ming-xue; Liu, Sheng

    2008-10-01

    The ethics of Western medicine and that of traditional Chinese medicine (TCM) developed separately in their own ways. The formation and development of ancient medical ethics of China were extensively and deeply influenced by Confucianism, Taoism, Buddhism and other religious thought, while the ancient ethic basis of western society was influenced by traditional Judaism, Christianism, Catholicism and other natural philosophical thinking of ancient Greece and Rome. With the progress of medical and life sciences, the medical ethics begins to transfer into the life ethics, thus giving rise to new questions in the ethics of Western medicine and TCM. PMID:19141202

  10. Three advantages of using traditional Chinese medicine to prevent and treat tumor

    Institute of Scientific and Technical Information of China (English)

    Chang-quan Ling; Xiao-qiang Yue; Chen Ling

    2014-01-01

    Traditional Chinese medicine (TCM), an important component of complementary and alternative medicine, has evolved over thousands of years with its own unique system of theories, diagnostics and therapies. TCM has been increasingly used in the last decades and become well known for its significant role in preventing and treating cancer. We believe that TCM possesses advantages over Western medicine in specific aspects at a certain stage of cancer treatment. Here we summarize the advantages of TCM from three aspects: preventing tumorigenesis; attenuating toxicity and enhancing the treatment effect; and reducing tumor recurrence and metastasis.

  11. Pulse waveform analysis as a bridge between pulse examination in Chinese medicine and cardiology.

    Science.gov (United States)

    de Sá Ferreira, Arthur; Lopes, Agnaldo José

    2013-04-01

    Pulse examination was probably the earliest attempt to distinguish between health and illnesses. Starting at the pre-Hippocratic era, Chinese medicine practitioners developed techniques for pulse examination and defined pulse images based on their perceptions of pulse waveforms at the radial artery. Pulse images were described using basic variables (frequency, rhythm, wideness, length, deepness, and qualities) developed under philosophical trends such as Taoism and Confucianism. Recent advances in biomedical instrumentation applied to cardiology opened possibilities to research on pulse examination based on ancient Chinese medical theories: the pulse wave analysis. Although strongly influenced by philosophy, some characteristics used to describe a pulse image are interpretable as parameters obtained by pulse waveform analysis such as pulse wave velocity and augmentation index. Those clinical parameters reflect concepts unique to Chinese medicine - such as yinyang - while are based on wave reflection and resonance theories of fluids mechanics. Major limitations for integration of Chinese and Western pulse examination are related to quantitative description of pulse images and pattern differentiation based on pulse examination. Recent evidence suggests that wave reflection and resonance phenomena may bridge Chinese medicine and cardiology to provide a more evidence-based medical practice. PMID:23546634

  12. Treatment of abdominal compartment syndrome in severe acute pancreatitis patients with traditional Chinese medicine

    OpenAIRE

    Zhang, Min-Jie; Zhang, Guo-Lei; Yuan, Wen-Bin; Ni, Jun; Huang, Li-Feng

    2008-01-01

    AIM: To investigate the therapeutic effect of traditional Chinese traditional medicines Da Cheng Qi Decoction (Timely-Purging and Yin-Preserving Decoction) and Glauber’s salt combined with conservative measures on abdominal compartment syndrome (ACS) in severe acute pancreatitis (SAP) patients.

  13. FOULING PREVENTION WITH FLUIDIZED PARTICLES IN EVAPORATION OF TRADITIONAL CHINESE MEDICINE EXTRACT

    Institute of Scientific and Technical Information of China (English)

    Mingyan Liu; Xiulun Li; Ruitai Lin; Wanda Nie; Rucheng Zhang; Ningsheng Ling

    2004-01-01

    The present investigation shows that comparing with the evaporation of vapor-liquid two-phase flow boiling system, heat transfer is enhanced by adding proper inert solid particles into the traditional Chinese medicine liquid which is under evaporation. As a result, fouling prevention effects are evident in such three-phase flow boiling evaporator.

  14. Chinese medicinal herbs for asymptomatic carriers of hepatitis B virus infection. Protocol for a Cochrane Review

    DEFF Research Database (Denmark)

    Liu, J P; Lin, Haili; McIntosh, H

    2000-01-01

    About 350 million people are chronically infected carriers of hepatitis B virus and are at a higher risk of serious illness and death from cirrhosis of the liver and liver cancer. Chinese medicinal herbs have been used widely for more than 2000 years to treat chronic liver disease....

  15. Methodology and Technology for Developing Multi-Component Chinese Medicine-Standardization and Resourcing

    Institute of Scientific and Technical Information of China (English)

    LIANG XinMiao; ZHANG XiuLi; XUE XingYa; FENG JiaTao

    2009-01-01

    @@ Presently,Traditional Chinese Medicine (TCM) is an important resource to treat many diseases,which has a long history in China,and is very complicated in chemical composition and pharmacology.Therefore,modernization of TCM is very necessary,including standardization,resourcing,quality control and research on chemical composition and pharmacology.

  16. Clinical Progress in the Treatment of Severe Acute Pancreatitis with Integrative Chinese and Western Medicine

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Severe acute pancreatitis (SAP), one of the crucial acute abdominal diseases, has high mortality for its quick initiation, severe condition, long duration, and frequent complication with multiple organ failure. In this paper, the clinical progress in the treatment of SAP with integrative Chinese and Western medicine is inspected and summarized.

  17. Dr. Lu Renhe's Experience in Treating Latent Nephritis with Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    Chen Jie

    2005-01-01

    @@ Dr. Lu Renhe of the First Clinical Medical College affiliated to Beijing University of Traditional Chinese Medicine has engaged in clinical practice,teaching and research for more than 40 years and accumulated rich experience of treating various kinds of nephritis, diabetes and their complications.The following is an introduction to his experience of treating latent nephritis.

  18. Effects of Immunopotentiator of the Traditional Chinese Medicine on T Lymphocytes in Chicken Blood

    Institute of Scientific and Technical Information of China (English)

    SHI Qiumei; LI Chunling; GAO Guisheng; SHEN Ping; TANG Shengling

    2008-01-01

    In order to investigate the mechanism of action of immunoenhancer, the effects of the traditional Chinese medicine immunopromoter on the quantity and the transformation rates of T lymphocytes in the chicken blood were determined. Total 120 chickens were randomly assigned into three groups. The 1% and the 0.5% of the Chinese medicine immunopromoter were added to the chicken drinking water, respectively. The quantity of T lymphocytes in each group was measured by a-Naphthyl acetate esterase (ANAE) staining. The results showed that the percentages of T lymphocytes of the treatment groups were significantly higher than that of the control group (P<0.05), and the percentage of the 1% group significantly higher than that of the 0.5% group (P<0.05). In conclusion, the transformation rates of T lymphocytes showed that the Chinese medicine immunopromoter had the significant enhancing effect on the transformation rates of T lymphoeytes of the treated chickens. The traditional Chinese medicine immunopromoter had the distinct function to promote the quantity and the transformation rate of T iymphocytes.

  19. Recent advances in ultra-high performance liquid chromatography for the analysis of traditional chinese medicine

    Science.gov (United States)

    Traditional Chinese medicines (TCMs) have been widely used for the prevention and treatment of various diseases for thousands of years in China. Ultra Performance Liquid Chromatography (UHPLC) is a relatively new technique offering new possibilities in liquid chromatography. This paper reviews recen...

  20. A General Introduction of HIV/AIDS Treatment with Traditional Chinese Medicine in China

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    This paper gives a general introduction of HIV/AIDS treatment with Traditional Chinese Medicine (TCM) in China during the past 20 years. Although the role of TCM in treatment of HIV/AIDS is promising, there is still a long way to go.

  1. Plasma metabolomics combined with personalized diagnosis guided by Chinese medicine reveals subtypes of chronic heart failure

    Directory of Open Access Journals (Sweden)

    Juan Wang

    2015-04-01

    Conclusion: This study suggests that combining metabolomics with traditional Chinese medicine diagnosis can reveal metabolic signatures for CHF syndrome subtypes. The plasma metabolites identified might be of special clinical relevance for subtypes of CHF, which could lead to further understanding of mechanisms involved and an improvement in personalized treatment for CHF.

  2. Fifty-Four Infantile Intractable Diarrhea Patients Treated with Integrated Traditional Chinese and Western Medicine

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Infantile intractable diarrhea (IID) was usually complicated with malnutrition, growth retardation and pulmonary infection, etc. It is difficult to cure, and mortality is rather high. The authors used integrated traditional Chinese and western medicine therapy to treat it, and satisfactory result has been obtained and reported as follows.

  3. Effective Application of Knowledge Management in Evidence-based Chinese Medicine: A Case Study

    Science.gov (United States)

    Allan, Garry; Li, Chun Guang; Xue, Charlie Changli

    2009-01-01

    Chinese medicine (CM) practice, as a knowledge-based industry, has not embraced knowledge management (KM) techniques widely. However, KM may facilitate the adaptation and promotion of evidence-based CM. A KM framework was introduced to its activities in evidence-based CM through the development of a CM portal. A codification strategy was used to codify and store knowledge systematically in a database. Several approaches were developed and implemented to address specific needs for CM such as centralizing the information, encouraging collective efforts, promoting integration of explicit and tacit knowledge, and developing a flexible technology and support system. Following the established KM framework, the RMIT Chinese Medicine Portal (www.chinese-medicine.com.au) was built up with four major components: organizational knowledge, knowledge workers, KM processes and information technology. Knowledge on Chinese herbs was classified into core, advanced and innovative categories, which involved the development of the monograph template. A working group was organized including CM, pharmacology and information technology professionals to implement this proposal with following sequential development stages: knowledge creation/acquisition, storage/organization, distribution and application. User interface and web language were also defined and accomplished. This case study demonstrates the applicability of KM in evidence-based CM through a multidisciplinary collaboration, such as, an effective collaboration between CM and information technology. The study also shows the potential of KM application in other disciplines of complementary and alternative medicine. PMID:18955285

  4. Literature review and analysis of the application of health outcome assessment instruments in Chinese medicine

    Institute of Scientific and Technical Information of China (English)

    Feng-bin Liu; Zheng-kun Hou; Yun-ying Yang; Pei-wu Li; Qian-wen Li; Nelson Xie; Jing-wei Li

    2013-01-01

    OBJECITVE:To evaluate the application of health assessment instruments in Chinese medicine.METHODS:According to a pre-defined search strategy,a comprehensive literature search for all articles published in China National Knowledge Infrastructure databases was conducted.The resulting articles that met the defined inclusion and exclusion criteria were used for analysis.RESULTS:A total of 97 instruments for health outcome assessment in Chinese medicine have been used in fundamental and theoretical research,and 14 of these were also used in 29 clinical trials that were randomized controlled trials,or descriptive or cross-sectional studies.In 2 152 Chinese medicine-based studies that used instruments in their methodology,more than 150 questionnaires were identified.Among the identified questionnaires,51 were used in more than 10 articles (0.5%).Most of these instruments were developed in Western countries and few studies (4%) used the instrument as the primary evidence for their conclusions.CONCLUSION:Usage of instruments for health outcome assessment in Chinese medicine is increasing rapidly; however,current limitations include selection rationale,result interpretation and standardization,which must be addressed accordingly.

  5. Neural Correlates of Traditional Chinese Medicine Induced Advantageous Risk-Taking Decision Making

    Science.gov (United States)

    Lee, Tiffany M. Y.; Guo, Li-guo; Shi, Hong-zhi; Li, Yong-zhi; Luo, Yue-jia; Sung, Connie Y. Y.; Chan, Chetwyn C. H.; Lee, Tatia M. C.

    2009-01-01

    This fMRI study examined the neural correlates of the observed improvement in advantageous risk-taking behavior, as measured by the number of adjusted pumps in the Balloon Analogue Risk Task (BART), following a 60-day course of a Traditional Chinese Medicine (TCM) recipe, specifically designed to regulate impulsiveness in order to modulate…

  6. Integrated Traditional Chinese and Western Medicine in Treating 37 Psoriatic Patients

    Institute of Scientific and Technical Information of China (English)

    LIU; Hong-pu

    2001-01-01

    Psoriasis is a kind of chronic relaptic skin disease, and at present there are no appropriate therapeutical methods. From March 1998 to May 1999, we used the traditional Chinese and western medicine (TCM-WM) approach in treating this disease, and satisfactory result was obtained. We clinically observed this method in treating psoriasis, with hemorrheological examinations performed, and it is reported as follows.

  7. [Research on collaborative innovation in traditional Chinese medicine of China based on patent cooperation network].

    Science.gov (United States)

    Li, Bei; Chen, Xiang-dong

    2015-03-01

    In the situation of global completion, collaborative innovation is becoming increasingly important because its advantage in risk avoiding and innovation efficiency. In order to explore the model of collaborative innovation and its evolution in traditional Chinese medicine of China, the cooperation in traditional Chinese medicine patents of China from 1985 to 2013 has been analyzed by using the method of scientometrics and social network analysis. It is proved that, though the number of grated cooperative patents has increased sharply during the last thirty years, the degree of cooperation innovation in traditional Chinese medicine of China is still not high. Moreover, in spite of the individual subject' s leading role in the past domestic collaborative innovation in traditional Chinese medicine of China, the institutions have been more and more powerful and achieved great improvement. At last, core institutions, represented by universities have played an important role in the collaborative innovation of domestic institutions, because they are key links between many institutions and promote the transferring and diffusion of knowledge. PMID:26226773

  8. Artemisinin-A Gift from Traditional Chinese Medicine to the World (Nobel Lecture).

    Science.gov (United States)

    Tu, Youyou

    2016-08-22

    Malaria has long been a devastating and life-threatening global epidemic disease in human history. Artemisinin, the active substance against malaria, was first isolated and tested in the 1970s in China. The important role played by traditional Chinese medicine in the discovery of artemisinin is described by Y. Tu in her Nobel Lecture.

  9. [Analysis on layout of traditional Chinese medicine industry based on location quotient].

    Science.gov (United States)

    Chen, Cong; Yu, Yuanyuan; Hu, Yuanjia; Wang, Yitao

    2012-03-01

    To observe the layout and evolution of the traditional Chinese medicine (TCM) medical industry, classify the industry by region and conduct a preliminary study on its professional advantages, competitiveness and possible cause by using the theory of location quotient in regional economics, in order to provide suggestions for the layout of the TCM medical industry.

  10. Randomized controlled trial assessing a traditional Chinese medicine remedy in the treatment of primary dysmenorrhea

    NARCIS (Netherlands)

    Kennedy, S.; Jin, X.; Yu, H.; Zhong, S.; Magill, P.; Vliet, T. van; Kistemaker, C.; Voors, C.; Pasman, W.

    2006-01-01

    A proof-of-concept study to assess the safety and efficacy of a traditional Chinese medicine formula as treatment for primary dysmenorrhea showed no statistically significant benefit over placebo. However, some efficacy parameters suggested possible superiority of the active treatment and so a large

  11. 中医药在非洲%Traditional Chinese medicine in Africa

    Institute of Scientific and Technical Information of China (English)

    代金刚; 朱建平; 宋丽娟; 肇红

    2014-01-01

    目的:研究中医药在非洲的传播、发展历史及现状和趋势,为更好地促进中非中医药合作提供参考。方法采用文献学和史学的研究方法,回顾中医药传入非洲的过程,并对典型事件进行分析。结果中医药传入非洲的历史要追溯到郑和下西洋时期。1963年,中国向非洲派遣医疗队,开启了中医药在非洲全面传播的历程,为中医国际发展做出了贡献。2005年,中国向非洲派遣了首批志愿者,中医向非洲传播有了新模式。结论通过援非医疗队、志愿者的教育培训、学术会议等中医药逐渐被非洲人民所熟知。目前,在政府推动下,中医药在非洲呈现出较快的发展势头,应该抓住机遇,促进中医药在非洲全面发展。%Objective Study on the spread and the development history of traditional Chinese medicine in Africa, as well as the present situation and trend, provide reference for better promoting China-Africa cooperation of traditional Chinese medicine. Methods Literature review and historical research methods are used to retrospect the process of traditional Chinese medicine into Africa, and analyze the typical event. Results traditional Chinese medicine was introduced into Africa's history dates back to the period of Zheng He's voyage. In 1963, China sent medical teams to Africa, the TCM comprehensive spread in Africa started. In 2005, China sent the first group of traditional Chinese medicine volunteers to Africa, which a new pattern of TCM spread. Conclusions By sending the medical teams, volunteers, and education training, academic conferences, traditional Chinese medicine was gradually known by the African people. TCM is developing rapidly by the supporting of the government. The opportunity should be seized to promote the comprehensive development of traditional Chinese medicine in Africa.

  12. Efficacy and Safety of Chinese Medicinal Herbs for the Treatment of Hyperuricemia: A Systematic Review and Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Jianping Lin

    2016-01-01

    Full Text Available Background. Chinese medicinal herbs may be useful for the treatment of hyperuricemia, but there has been no systematic assessment of their efficacy and safety. Objectives. To systematically assess the efficacy and safety of Chinese medicinal herbs for the treatment of hyperuricemia. Methods. Six electronic databases were searched from their inception to December 2015. Randomized controlled clinical trials (RCTs were included. Cochrane criteria were applied to assess the risk of bias. Data analysis was performed using RevMan software version 5.2. Results. Eleven RCTs with 838 patients were included. There was no significant difference in serum uric acid between Chinese medicinal herbs and traditional Western medicine (SME: 0.19, 95% CI: −0.04 to 0.43; p=0.10. In terms of overall efficacy, the Chinese medicinal herbs were significantly superior to Western medicine (RR: 1.11; 95% CI: 1.04 to 1.17; p=0.0007. The Chinese medicinal herbs were better than Western medicine in reducing the adverse reactions (RR: 0.30; 95% CI: 0.15 to 0.62; p=0.001. And all these funnel plots showed unlikelihood of publishing bias. Conclusions. The results indicate that Chinese medicinal herbs may have greater overall efficacy with fewer adverse drug reactions, although the evidence is weak owing to the low methodological quality and the small number of the included trials.

  13. Chinese translation of English textbooks on internal medicine from the 1850s to the 1940s.

    Science.gov (United States)

    Hong, Chuang-Ye; Wang, Fu-Mei

    2014-06-01

    During the 100 years from 1850 to 1949, six English textbooks on internal medicine were translated into Chinese and published. Publication of these books was a response to the increased demand for Chinese textbooks after the opening of several Western-style hospitals and medical schools in China where the instruction was in Chinese. Throughout this period, textbooks translated from English were regarded as symbols of mainstream and authority within medical communities in China. There was a shift of translators from British and American medical missionaries to Chinese medical elites. Publishers also changed from missionary hospitals or missionary organizations to the Chinese Medical Association, which was led by ethnic Chinese. After the 1950s, translation activity continued in Taiwan, but it was halted in China until after the Cultural Revolution. This paper provides bibliographic information about these books. The transition of medical authority in China during this 100-year period is also reviewed through the successive publication of translated textbooks on internal medicine. PMID:24820159

  14. [Establish research model of post-marketing clinical safety evaluation for Chinese patent medicine].

    Science.gov (United States)

    Zheng, Wen-ke; Liu, Zhi; Lei, Xiang; Tian, Ran; Zheng, Rui; Li, Nan; Ren, Jing-tian; Du, Xiao-xi; Shang, Hong-cai

    2015-09-01

    The safety of Chinese patent medicine has become a focus of social. It is necessary to carry out work on post-marketing clinical safety evaluation for Chinese patent medicine. However, there have no criterions to guide the related research, it is urgent to set up a model and method to guide the practice for related research. According to a series of clinical research, we put forward some views, which contained clear and definite the objective and content of clinical safety evaluation, the work flow should be determined, make a list of items for safety evaluation project, and put forward the three level classification of risk control. We set up a model of post-marketing clinical safety evaluation for Chinese patent medicine. Based this model, the list of items can be used for ranking medicine risks, and then take steps for different risks, aims to lower the app:ds:risksrisk level. At last, the medicine can be managed by five steps in sequence. The five steps are, collect risk signal, risk recognition, risk assessment, risk management, and aftereffect assessment. We hope to provide new ideas for the future research. PMID:26983223

  15. Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia

    Directory of Open Access Journals (Sweden)

    So Kwok-Fai

    2011-04-01

    Full Text Available Abstract Alzheimer's disease and vascular dementia are two major diseases associated with dementia, which is common among the elderly. While the etiology of dementia is multi-factorial and complex, neurodegeneration may be the major cause of these two diseases. Effective drugs for treating dementia are still to be discovered. Current western pharmacological approaches against neurodegeneration in dementia develop symptom-relieving and disease-modifying drugs. Current integrative and holistic approaches of Chinese medicine to discovering drugs for neurodegeneration in dementia include (1 single molecules from the herbs, (2 standardized extracts from a single herb, and (3 herbal formula with definite composition. This article not only reviews the concept of dementia in western medicine and Chinese medicine but also evaluates the advantages and disadvantages of these approaches.

  16. THE APPLICATION OF NANOTECHNOLOGY IN TRADITIONAL CHINESE MEDICINE%纳米技术在中医中的应用

    Institute of Scientific and Technical Information of China (English)

    刘晓辰; 张蓉; 杨云霜

    2014-01-01

    Nanotechnology provides new ideas and methods for the development of Traditional Chinese medicine. The application of nanotechnology in the traditional Chinese medicine diagnosis and treatment devices field was introduced and the nano traditional Chinese medicines were summarized and the enlightenment which come from nanotechnology for the traditional Chinese medicine philosophy was analysed. With the purposes of providing guidance for traditional Chinese medicine( TCM) continuously absorbing modern scientific and technological achievements, for traditional Chinese medicine ( TCM ) continuously developing and growing with the latest research technology and for traditional Chinese medicine( TCM) being geared to international standards.%纳米技术为中医药发展提供了新的思路和方法。文章通过介绍纳米技术在中医诊疗设备中的应用,概括纳米中药,分析纳米技术对中医理念的启示,从而为中医药学不断吸纳现代科技成果,使中医运用最新研究技术不断发展壮大并与国际接轨提供参考。

  17. Efficacy and safety of Chinese herbal medicine for benign prostatic hyperplasia: systematic review of randomized controlled trials

    Institute of Scientific and Technical Information of China (English)

    Chun Ho Ma; Wai Ling Lin; Sing Leung Lui; Xun-Yuan Cai; Vivian Taam Wong; Eric Ziea; Zhang-Jin Zhang

    2013-01-01

    Chinese herbal medicine is commonly used as a treatment for benign prostatic hyperplasia (BPH),but its efficacy and safety remain to be examined.To compare the efficacy and adverse events of Chinese herbal medicine alone or used adjuvantly with Western medications for BPH.Two independent reviewers searched the major electronic databases for randomized controlled trials comparing Chinese herbal medicine,either in single or adjuvant use with Western medication,with placebo or Western medication.Relevant journals and grey literature were also hand-searched.The outcome measures included changes in urological symptoms,urodynamic measures,prostate volume and adverse events.The frequency of commonly used herbs was also identified.Out of 13 922 identified citations of publications,31 studies were included.Eleven studies with a Jadad score ≥ 3 were selected for meta-analysis.Chinese herbal medicine was superior to Western medication in improving quality of life and reducing prostate volume.The frequency of adverse events in Chinese herbal medicine was similar to that of placebo and less than that of Western medication.The evidence is too weak to support the efficacy of Chinese herbal medicine for BPH due to the poor methodological quality and small number of trials included.The commonly used herbs identified here should provide insights for future clinical practice and research.Larger randomized controlled trials of better quality are needed to truly evaluate the efficacy of Chinese herbal medicine.

  18. Determination of Ochratoxin A Content in Chinese Medicinal Materials by Immunoaffinity Column Chromatography Purification-HPLC%免疫亲和柱层析净化-高效液相色谱法检测中药材中赭曲霉毒素A

    Institute of Scientific and Technical Information of China (English)

    李浩

    2015-01-01

    目的:建立中药材赭曲霉毒素A(OTA)污染检测的高效液相色谱(HPLC)法。方法经打粉的药材用甲醇-水(80:20)提取,经OTA免疫亲和柱层析净化,测定。色谱柱为Agilent Zorbax SB-C18柱(250 mm ×4.60 mm,5μm),流动相为乙腈-水-乙酸(49.5:49.5:1.0),流速为1 mL/min,荧光检测器检测,激发波长为333 nm,发射波长为460 nm,柱温为35℃,样品池温度为10℃,进样量为20μL。结果色谱峰面积与质量浓度之间有良好的线性关系,方法的检出限为0.2 ng/g,加样回收率为64.4%~106%,RSD为0~28.5%( n=3)。结论该方法操作简便、准确,重复性好,可用于中药材及中成药等药材中赭曲霉毒素A的测定。%Objective To establish a HPLC method for the determination of ochratoxin A(OTA)contamination in the Chinese medicinal ma-terials. Methods The powdered medicinal materials were extracted by methanol-water(80 :20),purified by the OTA immunoaffinity column and determined. The chromatographic column was with the Agilent Zorbax SB-C18 column(250 mm × 4. 60 mm,5 μm),the mobile phase was acetonitrile-water-acetic acid(49. 5 :49. 5 :1. 0),the flow rate was 1 mL/min,detected by the fluorescence detector,the excitation wave-length was 333 nm and the emission wavelength was 460 nm,the column temperature was 35 ℃,the sample temperature was 10 ℃ and the sample volume was 20 μL. Results The area of chromatographic peak and the concentration demonstrated a good linear relationship,its de-tection limit was 0. 2 ng/g,the recovery rate of samples was 64. 4% -106%,RSD was 0-28. 5%( n=3). Conclusion This method is sim-ple,accurate,better reproducible,which can be used for the determination of OTA in the Chinese medicinal materials.

  19. The symbolic context of Chinese medicine: a comparative approach to the study of traditional medical and psychiatric forms of care in Chinese culture.

    Science.gov (United States)

    Kleinman, A M

    1975-04-01

    This article explores a distinctly different aspect of Chinese medicine, and of health care in Chinese culture, from that receiving most attention and serious study at present in this country. It examines the symbolic structure and significance of illness and care in the Chinese context by (a) applying concepts developed in anthropology and the cross-cultural study of medicine and psychiatry; (b) examining recent studies of folk and popular forms of health care in contemporary Chinese communities; and (c) raising questions about the congnitive structure, cultural background, and bio-social significance of traditional Chinese healing beliefs and practices. An attempt is made to place this analysis in a comparative framework, so that Chinese cases can be related to health care systems in other cultural settings. PMID:47708

  20. Utilization of and Attitudes towards Traditional Chinese Medicine Therapies in a Chinese Cancer Hospital: A Survey of Patients and Physicians

    Directory of Open Access Journals (Sweden)

    Jennifer L. McQuade

    2012-01-01

    Full Text Available Background. In China, the use of traditional Chinese medicine (TCM is very popular, but little is known about how it is integrated with conventional cancer care. We conducted parallel surveys of patients and physicians on TCM utilization. Methods. Two hundred forty-five patients and 72 allopathic physicians at the Fudan University Shanghai Cancer Center completed questions on their use of and attitude towards TCM. Results. Patient mean age was 51, with 60% female. Eighty-three percent of patients had used TCM. Use was greatest for Chinese herbal medicine (CHM; 55.8%. Only 1.3% of patients used acupuncture and 6.8% Qi Gong or Tai Qi. Sixty-three percent of patients notified their oncologist about TCM use. The most common reason for use was to improve immune function. CHM was often used with a goal of treating cancer (66.4%, a use that 57% of physicians agreed with. Physicians were most concerned with interference with treatment, lack of evidence, and safety. Ninety percent of physicians have prescribed herbs and 87.5% have used TCM themselves. Conclusion. The use of TCM by Chinese cancer patients is exceptionally high, and physicians are generally well informed and supportive of patients’ use. Botanical agents are much more commonly used than acupuncture or movement-based therapies.

  1. [Discussion on research and development of new traditional Chinese medicine preparation process based on idea of QbD].

    Science.gov (United States)

    Feng, Yi; Hong, Yan-Long; Xian, Jie-Chen; Du, Ruo-Fei; Zhao, Li-Jie; Shen, Lan

    2014-09-01

    Traditional processes are mostly adopted in traditional Chinese medicine (TCM) preparation production and the quality of products is mostly controlled by terminal. Potential problems of the production in the process are unpredictable and is relied on experience in most cases. Therefore, it is hard to find the key points affecting the preparation process and quality control. A pattern of research and development of traditional Chinese medicine preparation process based on the idea of Quality by Design (QbD) was proposed after introducing the latest research achievement. Basic theories of micromeritics and rheology were used to characterize the physical property of TCM raw material. TCM preparation process was designed in a more scientific and rational way by studying the correlation among enhancing physical property of raw material, preparation process and product quality of preparation. So factors affecting the quality of TCM production would be found out and problems that might occur in the pilot process could be predicted. It would be a foundation for the R&D and production of TCM preparation as well as support for the "process control" of TCMIs gradually realized in the future.

  2. Application of Extraction Techniques in Sample Pretreatment for Test Method of Heavy Metal in Traditional Chinese Medicinal Materials%萃取技术在中药材重金属检测样品前处理中应用*

    Institute of Scientific and Technical Information of China (English)

    周骁腾; 侯静怡; 卢恒; 刘金欣; 魏英勤; 孟繁蕴(通讯作者)

    2013-01-01

    This paper summarizes the basic principle, approaches, and research development of analysis of heavy metals, and presents the prospective view for the determination of heavy metals in herbal medicines.Therefore, to develop a rapid, trace, low-cost method of extraction has been a tendency in heavy metals analysis.%  本文综述了重金属常用萃取技术的基本原理、实现方法、研究进展,并对其在中药材重金属测定的未来发展作了展望。认为建立快速、微量、低成本的萃取方法已成为重金属分析的研究热点和发展趋势。

  3. Methemoglobinemia development after ingestion of a chinese herbal medicine: A case report

    Directory of Open Access Journals (Sweden)

    Se Eun Hyun

    2010-03-01

    Full Text Available An 8-year-old girl visited the emergency room with perioral cyanosis and dyspnea, which had developed 20 hrs prior to the hospital visit. She had taken a Chinese herbal medication for 3 days prior to the onset of the symptoms. A co-oximeter examination revealed a methemoglobin level of 23.7%. An intravenous infusion of methylene blue was administered. Chemical analysis of the herbal medication revealed an ammonia (NH3 level of 239.41 mg/L. More studies are needed on the correlation between methemoglobinemia and the components of Chinese herbal medicines.

  4. Development and Current Status of National Cancer Center for Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    LI Jie; LIN Hong-sheng; HOU Wei; ZHANG Pei-tong; HUA Bao-jin

    2011-01-01

    @@ Chinese medicine (CM) is an important feature of cancer treatment in China.Especially in the last 10years, the effect of CM in cancer treatment has been of high concern and has been accepted by experts and patients locally and overseas.The oncology department (OD) of Guang'anmen Hospital (GAMH) of China Academy of Chinese Medical Sciences (CATCM),which will mark its 50th anniversary in 2013, is one of China's most-respected centers devoted exclusively to cancer patient care, research, education, and prevention through CM.It is located at the campus of GAMH,central Beijing.

  5. Danhong Injection (a Traditional Chinese Patent Medicine) for Acute Myocardial Infarction: A Systematic Review and Meta-Analysis

    OpenAIRE

    Pengda Liao; Lei Wang; Liheng Guo; Ruixiang Zeng; Juming Huang; Minzhou Zhang

    2015-01-01

    Objective. We aimed to systematically assess the efficacy and safety of Danhong injection (DHI) for acute myocardial infarction (AMI) patients. Methods. We searched several electrical databases and hand searched several Chinese medical journals. Randomized controlled trials (RCTs) comparing DHI plus conventional western medicine with conventional western medicine plus placebo and RCTs comparing DHI plus conventional western medicine with conventional western medicine were retrieved. Study scr...

  6. Search of new scintillation materials for nuclear medicine application

    CERN Document Server

    Korzhik, M V

    2000-01-01

    Oxide crystals have a great potential to develop new advanced scintillation materials which are dense, fast, and bright. This combination of parameters, when combined to affordable price, gives a prospect for materials to be applied in nuclear medicine devices. Some of them have been developed for the last two decades along the line of rear-earth (RE) garnet (RE/sub 3/Al/sub 5/O/sub 12/) oxiorthosilicate (RE/sub 2/SiO/sub 5/) and perovskite (REAlO/sub 3/) crystals doped with Ce ions. Among recently developed oxide materials the lead tungstate scintillator (PWO) becomes the most used scintillation material in high energy physics experiments due to its application in CMS and ALICE experiments at LHC. In this paper we discuss scintillation properties of some new heavy compounds doped with Ce as well as light yield improvement of PWO crystals to apply them in low energy physics and nuclear medicine. (18 refs).

  7. Reflections on the Past and Future of Integrative Medicine from a Lifelong Student of the Integration of Chinese and Western Medicine

    Institute of Scientific and Technical Information of China (English)

    David Eisenberg, M.D.

    2011-01-01

    This issue of the Chinese Joumal of Integrative Medicine includes a discussion of integrative medicine (IM)from various perspectives.Dr.Andrew Weil provides a comprehensive overview of the field from the US and Western perspectives(1);doctors Dobos and Tao(2) delineate those aspects of Westem IM which relate directly to Traditional Chinese Medicine (TCM);doctors Lee,Shin,et al(3) provide a systematic review of controlled trials of IM from the Korean literature;and Dr.Robinson contrasts IM in the West (United Kingdom) with IM in China(4).Importantly,each of these articles highlights the extraordinary relevance of TCM to emerging models of "IM" worldwide.

  8. Chinese Patent Medicine Tongxinluo Capsule for Hypertension: A Systematic Review of Randomised Controlled Trials

    Directory of Open Access Journals (Sweden)

    Jie Wang

    2014-01-01

    Full Text Available Background. This study was intended to evaluate the efficacy and safety of Tongxinluo capsule for hypertension. Search Strategy. We searched the Cochrane Central Register of Controlled Trials (CENTRAL in the Cochrane Library, The PubMed, EMBASE, Chinese Bio-Medical Literature Database (CBM, Chinese National Knowledge Infrastructure (CNKI, Chinese Scientific Journal Database, and Wan-fang Data started from the first of database to October 28, 2013. No language restriction was applied. We included randomized clinical trials testing Tongxinluo capsule against western medicine, Tongxinluo capsule versus placebo, and Tongxinluo capsule combined with western medicine versus western medicine. Study selection, data extraction, quality assessment, and data analyses were conducted according to the Cochrane standards. Results. 25 trials with 1958 participants were included. The methodological quality of the included trials was evaluated as generally low. The blood pressure (BP lowering effect of Tongxinluo capsule plus western medicine was significantly higher than that of western medicine (systolic blood pressure (SBP: −3.87, −5.32 to −2.41, P<0.00001; and diastolic blood pressure (DBP: −2.72, −4.19 to −1.24, P=0.0003. The BP also decreased significantly from baseline with Tongxinluo capsule than placebo (SBP: −9.40, −10.90 to −7.90, P<0.00001; and DBP: −11.80, −12.40 to −11.20, P<0.00001 or western medicine (SBP: −3.90, −4.93 to −2.87, P<0.00001; and DBP: −3.70, −3.83 to −3.57, P<0.00001. 12 trials reported adverse events without details. Conclusions. There is some but weak evidence about the effectiveness of TXL in treating patients with hypertension.

  9. Chinese patent medicine tongxinluo capsule for hypertension: a systematic review of randomised controlled trials.

    Science.gov (United States)

    Wang, Jie; Xiong, Xingjiang; Liu, Wei

    2014-01-01

    This study was intended to evaluate the efficacy and safety of Tongxinluo capsule for hypertension. Search Strategy. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library, The PubMed, EMBASE, Chinese Bio-Medical Literature Database (CBM), Chinese National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database, and Wan-fang Data started from the first of database to October 28, 2013. No language restriction was applied. We included randomized clinical trials testing Tongxinluo capsule against western medicine, Tongxinluo capsule versus placebo, and Tongxinluo capsule combined with western medicine versus western medicine. Study selection, data extraction, quality assessment, and data analyses were conducted according to the Cochrane standards. Results. 25 trials with 1958 participants were included. The methodological quality of the included trials was evaluated as generally low. The blood pressure (BP) lowering effect of Tongxinluo capsule plus western medicine was significantly higher than that of western medicine (systolic blood pressure (SBP): -3.87, -5.32 to -2.41, P < 0.00001; and diastolic blood pressure (DBP): -2.72, -4.19 to -1.24, P = 0.0003). The BP also decreased significantly from baseline with Tongxinluo capsule than placebo (SBP: -9.40, -10.90 to -7.90, P < 0.00001; and DBP: -11.80, -12.40 to -11.20, P < 0.00001) or western medicine (SBP: -3.90, -4.93 to -2.87, P < 0.00001; and DBP: -3.70, -3.83 to -3.57, P < 0.00001). 12 trials reported adverse events without details. Conclusions. There is some but weak evidence about the effectiveness of TXL in treating patients with hypertension. PMID:24693319

  10. Assessment of the Reporting Quality of Randomized Controlled Trials on Treatment of Coronary Heart Disease with Traditional Chinese Medicine from the Chinese Journal of Integrated Traditional and Western Medicine: A Systematic Review

    OpenAIRE

    Fang-fang Fan; Qin Xu; Qi Sun; Sheng-jun Zhao; Ping Wang; Xue-rui Guo

    2014-01-01

    BACKGROUND: Due to language limitations, little is known about the reporting quality of randomized clinical trials (RCTs) on the treatment of coronary heart disease (CHD) with traditional Chinese medicine (TCM) in Chinese Journal of Integrated Traditional and Western Medicine (CJITWM). OBJECTIVE: In this study, we utilized the CONSORT 2010 statement to understand the reporting quality of RCTs on CHD with TCM from the CJITWM. METHODS: The China National Knowledge Infrastructure (CNKI) electron...

  11. The AMS/Paterson Lecture: becoming alternative? Modern transformations of Chinese medicine in China and in the United States.

    Science.gov (United States)

    Furth, Charlotte

    2011-01-01

    "Becoming Alternative" offers an overview of the transformations of Chinese medicine at home and abroad since the mid-19th century. After coming into contact with biomedicine, China's indigenous medicine was redefined in terms of national culture and history on the one hand, and a competitive alternative science on the other. Reimagined in terms of scientific syncretism in the PRC, and embraced as a counter-cultural alternative to bio-medicine in the United States, the medicine we call "Chinese" today emerges as a pluralistic system with global reach involving complex accommodations with local medical cultures and institutions both at home and abroad.

  12. [Brain governing mind theory in traditional chinese medicine].

    Science.gov (United States)

    Han, Zhen-Ting

    2012-07-01

    The "Heart Governing Mind" theory has been in the mainstream of visceral manifestation State Doctrine for a long time, but the "Brain Governing Mind" theory is also the traditional thought in Chinese culture. A large number of recordings about the brain in medical or non-medical books from Pre-Qin to the Qing dynasty reflected people's deeper and deeper understanding of the relation between the brain and mind. In order to provide a theoretical guidance for cerebral pathology, we should have a correct understanding of the important role of the brain in life activities, keep developing the "Brain Governing Mind" theory and understand the relationship between the brain and taiji, yinyang, wuxing, viscera, meridians and Guanqiao five apertures and nine orifices. PMID:23336273

  13. The treatment and research for posttraumatic stress disorder with Chinese medicine

    Directory of Open Access Journals (Sweden)

    Yong-Hua Zhang

    2014-12-01

    Full Text Available There is no disease called posttraumatic stress disorder (PTSD in traditional Chinese medicine (TCM. However, Huangdi's Canon of Medicine written in about 200 BC, one of the most famous TCM classics, recorded diseases with similar etiology, pathogenesis, and clinical symptoms. Moreover, contemporary TCM also attaches great importance to diseases caused by trauma. Especially after 2008, there is a mini-rush of study on PTSD as a result of Sichuan earthquake. Referring to ancient and modern literature, we summarize the TCM treatment of PTSD and wish to contribute to the further study on TCM remedy for PTSD.

  14. Traditional Chinese patent medicines for cancer treatment in China: a nationwide medical insurance data analysis

    OpenAIRE

    Wu, Min; Lu, Peng; Shi, Luwen; Li, Shao

    2015-01-01

    Based on the nationwide survey into inpatients' utilization of the health service covered by China's urban basic medical insurance from 2008 to 2010, we analyzed the use rate, cancer profile and combined use of anticancer Chinese patent medicines (CPMs) on 51,382 insured cancer patients by using statistical, bi-clustering and network methods. We found that 42.4% of 51,382 cancer patients used 33 anticancer CPMs, and 51.7% used 71 anticancer Western medicines (WMs). The CPMs were most often us...

  15. Study of Traditional Chinese Medicine--Which Is After All the Right Way?

    Institute of Scientific and Technical Information of China (English)

    CHEN Ke-ji; LI Li-zhi

    2005-01-01

    @@ The study of traditional Chinese Medicine (TCM) with modern research approach has been ongoing for more than half a century. Although great achievement has been made, the progress is less significant when compared with the advance made in other scientific disciplines such as Western medicine (WM). TCM development has reached a crucial point in the era of rapid development of modern sciences and technologies. Whether or not and how to incorporate contemporary sciences and advanced technologies into the study of TCM has been a hot topic discussed in the academics in China.

  16. Dendritic Cells as a Pharmacological Target of Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    Xin Chen; Lu Yang; O. M. Zack Howard; Joost J. Oppenheim

    2006-01-01

    Dendritic cells (DCs) represent a heterogeneous population of professional antigen-presenting cells (APCs) that play a central role in the initiation and regulation of immune responses. There is considerable evidence that DCs can be used as therapeutic targets for pharmacological modulation of immune responses. Traditional Chines emedicine (TCM) has a long-standing history of using herbal medicine in the treatment of variety of human diseases.Many of the clinical effects of TCM have reportedly been attributed to the up- or down-regulation of immune responses. Accumulating evidence indicates that TCM and its components can interfere with immune responses at the earliest stage by targeting key functions of DCs. Here, we review those published studies of TCM with respect to their effects on immunobiological functions of DCs. Investigations based on both chemical entities derived from TCM as well as TCM herbal mixtures are presented. These studies suggest that various TCM herbal medicines have the capacity to inhibit or promote major functions of DCs, such as differentiation, maturation, cytokine production, survival, antigen uptake and presentation as well as trafficking. These studies have revealed novel biological effects of TCM and documented the utility of this approach to discover novel biological modifier of DC functions derived from natural sources.

  17. [Cultivation strategy and path analysis on big brand Chinese medicine for small and medium-sized enterprises].

    Science.gov (United States)

    Wang, Yong-Yan; Yang, Hong-Jun

    2014-03-01

    Small and medium-sized enterprises (SMEs) are important components in Chinese medicine industry. However, the lack of big brand is becoming an urgent problem which is critical to the survival of SMEs. This article discusses the concept and traits of Chinese medicine of big brand, from clinical, scientific and market value three aspects. Guided by market value, highlighting clinical value, aiming at the scientific value improvement of big brand cultivation, we put forward the key points in cultivation, aiming at obtaining branded Chinese medicine with widely recognized efficacy, good quality control system and mechanism well explained and meanwhile which can bring innovation improvement to theory of Chinese medicine. According to the characters of SMEs, we hold a view that to build multidisciplinary research union could be considered as basic path, and then, from top-level design, skill upgrading and application three stages to probe the implementation strategy. PMID:25204160

  18. Multiresidue analysis of pesticides in traditional Chinese medicines using gas chromatography - negative chemical ionization tandem mass spectrometry

    Science.gov (United States)

    In this study, a residue analysis method for the simultaneous determination of 107 pesticides in the traditional Chinese medicines (TCMs), Angelica sinensis, Angelica dahurica, Leonurus heterophyllus Sweet, Pogostemon cablin, and Lonicera japonica Thunb, was developed using gas chromatography couple...

  19. [Cultivation strategy and path analysis on big brand Chinese medicine for small and medium-sized enterprises].

    Science.gov (United States)

    Wang, Yong-Yan; Yang, Hong-Jun

    2014-03-01

    Small and medium-sized enterprises (SMEs) are important components in Chinese medicine industry. However, the lack of big brand is becoming an urgent problem which is critical to the survival of SMEs. This article discusses the concept and traits of Chinese medicine of big brand, from clinical, scientific and market value three aspects. Guided by market value, highlighting clinical value, aiming at the scientific value improvement of big brand cultivation, we put forward the key points in cultivation, aiming at obtaining branded Chinese medicine with widely recognized efficacy, good quality control system and mechanism well explained and meanwhile which can bring innovation improvement to theory of Chinese medicine. According to the characters of SMEs, we hold a view that to build multidisciplinary research union could be considered as basic path, and then, from top-level design, skill upgrading and application three stages to probe the implementation strategy.

  20. 振兴绿色中药农业发展研究报告%Research Report on Revitalization of Green Chinese Medicine Agriculture Development

    Institute of Scientific and Technical Information of China (English)

    纪宝玉; 裴莉昕; 许东升; 董诚明

    2014-01-01

    振兴绿色中药农业发展,需要继续加强 GAP 关键技术的推广和科技示范园区的建设;加强大品种的开发,创立优势品牌;重视中药材品种选育工作;引导企业的积极参与;建立起一套具有竞争力的中医药教育、科研开发、种植生产体系,积极扶持和组建一批中药规模化生产基地和龙头企业,使我国的中药农业实现跨越性发展。%The revitalization of Chinese medicine green agriculture development needs to continue to strengthen the promotion the key technology of GAP,and the construction of the science and technology demonstration garden;Enhance the development of large varie-ties,and create brand advantage;Attaches great importance to the traditional Chinese medicinal materials variety breeding work;Guide enterprises to active participation;Set up a competitive education of Chinese medicine,scientific research and development,plant pro-duction system,and actively nurture and form a group of Chinese medicine large-scale production base and leading enterprises,which make Chinese medicine agricultural realize the cross-cutting development.

  1. The construction of gan zhu shuxie (liver controlling conveyance and dispersion), as viewed from the contemporary teaching material of basic theory of Traditional Chinese Medicine%从中医基础理论类教材看“肝主疏泄”的建构

    Institute of Scientific and Technical Information of China (English)

    靳宇智; 马燕冬

    2014-01-01

    在现行中医基础理论类教材中,“肝主疏泄”涉及到对人体整体生理功能、消化功能、精神情志活动、血液循环、水液代谢、生殖功能多方面的功能调节.从此类教材来看,学术界对“肝主疏泄”理论的建构,可分为3个阶段:20世纪50-70年代,教材中基本未提及“肝主疏泄”理论;20世纪70-80年代中期,各版本教材中关于“肝主疏泄”的论述并不统一;20世纪80年代中期后至今,教材中对“肝主疏泄”的论述理论基本趋于统一.%In current teaching material of basic theory of Traditional Chinese Medicine (TCM),the theory of "liver controlling conveyance and dispersion" covers the functional adjustment of many aspects,including the overall human physiology,digestion,mental activity,blood circulation,water metabolism and reproduction.Through the research of the teaching material of TCM basic theory since the establishment of the People' s Republic of China,it can be considered that there are 3 stages for the construction of the theory of "liver controlling conveyance and dispersion".From the 1950s to 1970s,this theory was not mentioned in any teaching materials; from the 1970s to the mid 1980s,different views about this theory can be seen in the teaching materials; after the mid 1980s,this theory in the teaching materials became gradually basically identical.

  2. The Efficacy of Chinese Medicinal Herbs towards Grape Phylloxera (Daktulosphaira vitifoliae Fitch) (Hemiptera, Phylloxeridae).

    Science.gov (United States)

    Liu, Yongqiang; Wang, Zhongyue; Su, Junping; Liu, Weiwei; Hussain Dhiloo, Khalid; Guo, Yuyuan

    2015-01-01

    Bio-insecticidal effects of seven Chinese medicinal herbs on mortality, fecundity, developmental periods and life table parameters of the grape phylloxera were investigated. In an excised root bioassay experiment aqueous extracts from seven Chinese medicinal herbs increased grape phylloxera first instar mortality (26.00-38.50%) compared to other instars. The intrinsic rate of increase (rm), finite rate of increase (λ), fecundity rate and net reproductive rate (R0) were significantly reduced by A. bidentata, A. tataricus, O. basilicum, P. frutescens and N. cataria. In a glasshouse pot trial, eggs, nymphs, adults and total population were significantly reduced before population establishment compared to those after its population established, by A. bidentata, A. tataricus and O. basilicum. Overall, A. bidentata, A. tataricus and O. basilicum can be used to suppress all life-stages of grape phylloxera. PMID:26186216

  3. The Efficacy of Chinese Medicinal Herbs towards Grape Phylloxera (Daktulosphaira vitifoliae Fitch (Hemiptera, Phylloxeridae.

    Directory of Open Access Journals (Sweden)

    Yongqiang Liu

    Full Text Available Bio-insecticidal effects of seven Chinese medicinal herbs on mortality, fecundity, developmental periods and life table parameters of the grape phylloxera were investigated. In an excised root bioassay experiment aqueous extracts from seven Chinese medicinal herbs increased grape phylloxera first instar mortality (26.00-38.50% compared to other instars. The intrinsic rate of increase (rm, finite rate of increase (λ, fecundity rate and net reproductive rate (R0 were significantly reduced by A. bidentata, A. tataricus, O. basilicum, P. frutescens and N. cataria. In a glasshouse pot trial, eggs, nymphs, adults and total population were significantly reduced before population establishment compared to those after its population established, by A. bidentata, A. tataricus and O. basilicum. Overall, A. bidentata, A. tataricus and O. basilicum can be used to suppress all life-stages of grape phylloxera.

  4. Pathogenetic Regulation of Female Precocious Puberty and the Mechanism of Therapy with Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    cai; de-pei

    2001-01-01

    In recent ten-odd years the pathogenetic regulation of female idiopathic precocious puberty was studied in our hospital, in terms of the function of hypothalamic-pituitary-gonadal axis (HPG axis) and the status of skeletal development as indicators. The therapy with Chinese herbal medicine (CHM) in predominance was formulated, according to our understanding of the regulation and Syndrome Differentiation of traditional Chinese medicine (TCM). It has been clinically verified that the therapy could successfully modulate the course of pubertal development and optimize skeletal development in children with precocious puberty. The mechanism of effectiveness of the drugs has been further studied focusing on the neuroendocrine regulation and gene expression with modern medical techniques.……

  5. Pathogenetic Regulation of Female Precocious Puberty and the Mechanism of Therapy with Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    蔡德培; 季志英; 陈伯英; 张炜

    2001-01-01

    @@In recent ten-odd years the pathogenetic regulation of female idiopathic precocious puberty was studied in our hospital, in terms of the function of hypothalamic-pituitary-gonadal axis (HPG axis) and the status of skeletal development as indicators. The therapy with Chinese herbal medicine (CHM) in predominance was formulated, according to our understanding of the regulation and Syndrome Differentiation of traditional Chinese medicine (TCM). It has been clinically verified that the therapy could successfully modulate the course of pubertal development and optimize skeletal development in children with precocious puberty. The mechanism of effectiveness of the drugs has been further studied focusing on the neuroendocrine regulation and gene expression with modern medical techniques.

  6. Treatment of Severe Post-kidney-transplant Lung Infection by Integrative Chinese and Western Medicine

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Objective: To explore treatments of severe post-kidney-transplant lung infection by integrative Chinese and Western medicine (ICWM), in order to elevate the curing rate as well as to lower the death rate. Methods: Based on conventional ways of Western medical treatments of 18 cases of severe post-kidney-transplant lung infection, such as putting the patients in single individual ward, antibiotics to prevent infection, respiratory machines, blood filtration, nutritional support, steroids, and maintaining electrolytes balance, we applied integrated Chinese medicinal treatments, like altering conventional prescription "pneumonia Ⅲ ", and conducted clinical observation of effectiveness, and indexes including white blood cell (WBC), neutrophilic granulocyte, blood urea nitrogen (BUN), blood creatinine (Cr), etc. Results: Of the 18cases studied, 7 were already cured, 8 proved the treatment effective, 3 died. All clinical indexes had statistically significant changes compared with those of before treatment (P<0.01). Conclusion: ICWM can increase curing rate and lower death rate.

  7. [Crisis and vitality: new evaluation of the development of the Chinese Medicine in the Republican period].

    Science.gov (United States)

    Zheng, Hong

    2015-05-01

    By investigating the development process of the Republic of China with pluralistic perspective, it can be seen that contemporary TCM was undergoing the crises of theory, value, and survival, and rights which were a necessary steps when entering a new historical stage. The mainstream of the development of TCM during this period included fighting for its existence and self-strengthening, which had gained five achievements, including prevention of the attempts of abolishing TCM; involvement into the modern national political system; inheritance of the integrity of academic system; the formation of embryonic shape of new business, and the experience attained in the integration of Chinese and Western Medicine. All these manifested its strong vitality, though it was somewhat limited in its developmental level. It had laid down the basis for the embryonic stage of developmental model of Chinese medicine after the twentieth century.

  8. Traditional Chinese medicine for treatment of liver diseases:progress, challenges and opportunities

    Institute of Scientific and Technical Information of China (English)

    Chang-qing Zhao; Yang Zhou; Jian Ping; Lie-ming Xu

    2014-01-01

    Traditional Chinese medicine (TCM) is commonly used in treating liver diseases worldwide, especially in China. The advantages of using TCM for treatment of liver diseases include: protecting hepatocytes, inhibiting hepatic inlfammation and antiifbrosis in the liver. In this article, we introduce TCM herbal preparations from the Chinese materia medica (such as Fuzheng Huayu) that are typically used for the treatment of liver diseases. Literature surrounding the mechanisms of TCM therapy for treatment of liver diseases is presented and discussed. We propose that side effects of herbal compounds are often under-appreciated, and that more care should be taken in the prescription of potentially hepatotoxic medicines. Further, to deepen the understanding of TCM mechanisms, new techniques and methodologies must be developed. Future studies will lead to the enhancement of clinical outcomes of TCM. As complementary and alternative therapies, TCMs will play an expanding role in the future of liver disease treatment.

  9. [Brief discourse on development of psychology of modern traditional Chinese medicine].

    Science.gov (United States)

    Zhang, Jinxia; Li, Peng; Wang, Zhen'e

    2014-05-01

    In 1980, Wang Miqu proposed the concept of "The Psychology of Traditional Chinese Medicine (TCM Psychology)". In 1985, "The First National Symposium on Psychology of Traditional Chinese Medicine" was held, and the concept of TCM Psychology was put forward in the symposium, thus declaring the establishment of TCM Psychology, a new disciplinary branch. Since then, 12 national or international academic symposia of TCM Psychology were convened nationwide. Based on inheriting the original TCM, by means of exploring, sorting out and improving, and by combining and integrating with psychology and medical psychology, the theory of TCM Psychology was thus gradually innovated, and a systematic knowledge of TCM Psychology was set up and utilized in the clinical practice extensively.

  10. [Study on path of transforming traditional Chinese medicine research achievement into guideline].

    Science.gov (United States)

    Zhang, Wen; Xie, Yan-Ming; Yuwen, Ya

    2014-09-01

    At present, a number of scientific research achievements has been formed. Scientific achievement is the crystallization of great efforts from scientific workers, and it's also the valuable treasure of human civilization. Standardization is an important way to promote the international communication of Chinese medicine, and it's significant in boosting China's scientific and technological progress, improving market competitiveness and promoting international trade. Transformation of scientific research to the guideline is not only beneficial to improving the technology content of the standard, but also to the conversion from scientific research achievements into productivity. Therefore, only by absorbing the advanced scientific and technological achievements, reproducing the theory of traditional Chinese medicine (TCM) and medical technology in standard form, can make TCM keep pace with the times. This study preliminarily explores for the method to transform scientific research achievements into guideline, in order to provide reference for the future technical specifications, thus to further the development of TCM. PMID:25532407

  11. [Factional disputes on the retention or abolition of traditional Chinese medicine within the National Government].

    Science.gov (United States)

    Hao, Xian-zhong; Zhu, De-pei

    2008-07-01

    The disputes between Western and traditional Chinese medicine (TCM) started at the turn of late Qing Dynasty to early Republican China, intensified in the period of construction of National Government at Nanking, lasting for several years. The scope of dispute also extended from the initial medical area to the mass media, and even to the government interior factions. The form of the combat also changed from the debates of original scientific theory to the confrontation of political ideology. It was the government interior factional disputes which caused "the case of abolition of the traditional Chinese medicine" to abort objectively, with the difficult advent of the regulations which saved TCM, to certain degree, from vanishing. PMID:24915651

  12. Analysis of drugs illegally added into Chinese traditional patent medicine using surface-enhanced Raman scattering.

    Science.gov (United States)

    Zhang, Yan; Huang, Xiaoyan; Liu, Wenfang; Cheng, Zeneng; Chen, Chuanpin; Yin, Lihui

    2013-01-01

    Illegal chemicals, which could cause unpredictable side effects, may be added into traditional Chinese medicine (TCM) for a rapid healing effect. In this report, a surface-enhanced Raman scattering (SERS) analysis method for five kinds of illegally added drugs (rosiglitazone maleate, phenformin hydrochloride, metformin hydrochloride, pioglitazone hydrochloride and sibutramine hydrochloride) in Chinese traditional patent medicine (CTPM) has been demonstrated, including simultaneous detections of drug mixtures with CTPM. Silver colloidal, prepared by a sodium citrate reaction, was used as a SERS substrate. The optimum pH condition for each drug has also been explored because of its combined effect on protonation, surface charge, repulsion of an analyte and nanoparticles. Furthermore, the simultaneous detection of two or three kinds of these chemicals has been carried out. Characteristic peaks are employed for qualitative analysis. This is the first research using SERS for the analysis of drug mixtures in CTPM without any separation process. PMID:24107564

  13. Study on material basis of Dracocephalum moldavica for protecting cardiomyocyte against hypoxia/reoxygenation injury by traditional Chinese medicine serum chemical and pharmacological methods%基于中药血清化学及血清药理学方法探讨香青兰保护心肌细胞缺氧/复氧损伤物质基础

    Institute of Scientific and Technical Information of China (English)

    田友清; 尚靖; 何婷; 蔡旻煊; 阿布卡德

    2012-01-01

    Objective: To study the material basis of Dracocephalum moldavica for protecting cardiomyocyte against hypoxia/ reoxygenation injury by using traditional Chinese medicine (TCM) serum chemical and pharmacological methods. Method; The extract of D. Moldavica (DME) and its content absorbed into blood were determined, while blank serum and medicinal serum of rats before and after intragastrical administration of DME were also compared by HPLC. The Na2S2 O4, or N2-based hypoxia/reoxygenation injury model was established by cultivating primary neonate rat cardiomyocytes or H9c2 cells in vitro. Cell viability, LDH release, T-SOD activity , MDA production and apoptosis were detected to learn the effect of DME, medicated serum and different treatments of medicinal serums under different dosage and action duration of DME on cardiomyocyte against hypoxia/reoxygenation injury. Result: Four transitional components of DME absorbed into blood after intragastrical administration were found, three of which were original components and one possible metabolite. Furthermore, compared with the model group or the blank serum group, LDH release and MDA production (P <0.05, P <0.01) of DME extracts, medicated serum or different treatments of medicinal serum under different dosage and action duration of DME. However, T-SOD and cell viability were improved significantly (P < 0. 05, P < 0. 01) , while apoptosis of cardiomyocytes were also obviously inhibited. Conclusion: The four components absorbed into blood are probably the material basis of DME used for protecting cardiomyocyte agastin hypoxia/reoxygenation injury.%目的:利用中药血清化学及血清药理学方法探讨香青兰保护心肌细胞缺氧/复氧损伤的物质基础.方法:测定和比较香青兰提取物及其灌胃给药前后大鼠空白血清和含药血清的HPLC,寻找香青兰入血成分;体外培养乳大鼠原代心肌细胞及H9c2细胞,用Na2S2O4或N2为缺氧剂建立缺氧/复氧损伤模型,以细

  14. [The Theory and Practice of Health Cultivation Qigong Exercise in Traditional Chinese Medicine].

    Science.gov (United States)

    Chang, Mei-Ying

    2015-12-01

    The health cultivation qigong exercise in traditional Chinese medicine refers to a traditional, integrated method of illness prevention and body strengthening, which promotes the functions of qi and the blood, smooths the meridians (energy channels), and balances the viscera and bowels through the regulation of the mind, the breathing, and the body. The concept of using qi to cultivate human life is part of the health cultivation practices of ancient Chinese codes and of Chinese medicine. This concept includes the principles, methods, essences, and clinical applications of the practice. In addition, traditional health cultivation references the concepts of yinyang, viscera and bowels, qi and blood, meridians, and essential energy spirit theory in order to explain the human biological phenomena, the theoretical and practical perspectives of qigong, and the basis of the treatment principle. The health cultivation qigong exercise of Chinese medicine utilizes the concept of the "unity of nature and human beings" in traditional Chinese thinking in its practice, which emphasizes the conformity to nature and seasons. In order to fully leverage the benefits from the purpose of health cultivation in qigong practice, the priority is to understand the health cultivation mechanism, the essentials/matters, and the precautions of qigong practices. Recently, the evidence regarding both the biological and the psychological benefits of qigong practices have been demonstrated in numbers of research articles. In particular, qigong is currently considered to be one of the best mild exercises that is suited to all age groups. Professional nurses are suggested to include the health cultivation qigong exercise as part of activities that target health improvement and illness prevention. Due to the diversity in qigong as practiced by different health cultivation qigong exercise sects, it is essential to accumulate more clinical evidence by conducting greater numbers of rigorous studies

  15. [Preliminary application of atomic force microscopy on identification of native habitat of Chinese medicine decoction pieces].

    Science.gov (United States)

    Jiao, Ligong; Liu, Jing; Chen, Hao; Liao, Fulong; Han, Dong

    2012-04-01

    Identification of the native habitat of Chinese medicine decoction pieces plays an important role in the use of Chinese Heber medicine. However, the traditional method always based on subjective description, lack of quantitative information. In this study, nanomechanical analysis of Ophiopogonis Radix, Polygonati Odorati Rhizoma and Curcumae Aromaticae Radix coming from different districts was carried out by using the force-distance curve of atomic force microscopy (AFM), including stiffness (represented by the slope of the force curve) and adhesion work (calculated via the adhesion area of the retrace line in force-distance curve). The results showed that the Ophiopogonis Radix from Sichuan province (slope 0.03 +/- 0.001) was significantly stiffer but less sticky [adhesion work 393.98 +/- 49.21 x 10(-10)) J] in comparison with that from Hubei province [slope 0.018 +/- 0.001, adhesion work (985.67 +/- 91.61) x 10(-10) J]; the Polygonati Odorati Rhizoma Hunan province was stiffer (slope 0.03 +/- 0.002) and stickier [adhesion work (413.67 +/- 92.58) x10(-10) J] than that from Dongbei province [slope 0.019 +/- 0.002, adhesion work (27.37 +/- 11.05) x 10(-10) J]; the Curcumae Aromaticae Radix from Sichuan province was also stiffer (slope 0.019 +/- 0.0017) but less stickier [adhesion work (1179.79 +/- 225.05) x 10(-10) J] than that from Hubei province [slope 0.013 +/- 0.0006, adhesion work (2831.27 +/- 93.71) x 10(-10)]. It is indicated that changes in mechanical properties of Chinese medicine decoction pieces correlate well with their origin. This method may provide quantitative information for the identification of the native habitat of Chinese medicine decoction pieces. PMID:22779365

  16. Professor Dr. Chen Anmin voted in as the new president of Chinese German Society of Medicine

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ On June 24th 2006, Chinese German Society of Medicine (Chinesisch-Deutsche Gesellschaft für Medizin, CDGM) convened a representative assembly in Wuhan. Prof. Dr. Chen Anmin was elected as the new president of CDGM, who is also the director of Tongji Hospital, Tongji Medical College of Huazhong University of Science & Technology. In the mean time the Director Council and the Permanent Director's council were also selected. Mr.Dong Weiguo has been voted in as secretary-general.

  17. Innovative Thoughts on Treating Diabetes from the Perspective of Traditional Chinese Medicine

    OpenAIRE

    Bing Pang; Qiang Zhou; Tian-Yu Zhao; Li-Sha He; Jing Guo; Hong-Dong Chen; Lin-Hua Zhao; Xiao-Lin Tong

    2015-01-01

    The rapidly increasing incidence of diabetes mellitus (DM) is becoming a major public health issue. As one of the important parts in complementary and alternative therapies, traditional Chinese medicine (TCM) is promising in treating DM. In this review, we summarize new thoughts on treating DM that aim to improve the clinical efficacy of TCM from the perspectives of principle, methods, formula, herbs, and doses. Our approach is as follows: principle: we use a combination of symptoms, syndrome...

  18. Trains of Thought in Treating Infectious Atypical Pneumonia with Integrative Chinese and Western Medicine Approach

    Institute of Scientific and Technical Information of China (English)

    林琳

    2003-01-01

    @@ Infectious atypical pneumonia (also called severe acute respiratory syndrome, SARS by WHO) is a new type of infectious disease, whose disease condition is fierce and ferocious, rapid in changing, seriously threatened human health and life. The author has treated around 200 SARS patients in Guangzhou and Hong Kong with integrative Chinese and western medicine (ICWM) approach from January 2003till present. Now I would like to make a comment on ICWM in treating SARS.

  19. NINETY-THREE CASES OF GASTROPTOSIS TREATED BY ACUPUNCTURE COMBINED WITH CHINESE HERBAL MEDICINE

    Institute of Scientific and Technical Information of China (English)

    HAN Xin-qiang; HAN Bao-ru; HAN Yan-ru

    2006-01-01

    @@ Gastroptosis refers to prolapse of the stomach to an abnormal position manifested clinically by distending pain below the xiphoid process, hypochondriac fullness, chest stuffiness, abdominal distention and straining sensation,which is mainly caused by reduced tensity, lack of fat of the abdominal wall, relaxed muscles and decreased abdominal pressure. The authors have treated 93 cases of gastroptosis by applying acupuncture combined with Chinese herbal medicine and achieved quite satisfactory therapeutic results reported as follows.

  20. Heavy Metal and Pesticide Content in Commonly Prescribed Individual Raw Chinese Herbal Medicines

    OpenAIRE

    HARRIS, Eric S. J.; Cao, Shugeng; Littlefield, Bruce A.; Craycroft, Jane A.; Scholten, Robert; KAPTCHUK, Ted; Fu, Yanling; Wang, Wenquan; Liu, Yong; Chen, Hubiao; Zhao, Zhongzhen; Clardy, Jon; Woolf, Alan D.; Eisenberg, David M.

    2011-01-01

    Heavy metal and pesticide contamination has previously been reported in Chinese Herbal Medicines (CHMs), in some cases at potentially toxic levels. This study was conducted to determine general patterns and toxicological significance of heavy metal and pesticide contamination in a broad sample of raw CHMs. Three-hundred-thirty-four samples representing 126 species of CHMs were collected throughout China and examined for arsenic, cadmium, chromium, lead, and mercury. Of the total, 294 samples ...

  1. 50 Cases of Pointed Condyloma Treated by Surgery Combined with External Washing with Chinese Herbal Medicine

    Institute of Scientific and Technical Information of China (English)

    杨小毛; 曾佳; 龙亚军

    2001-01-01

    @@ Pointed condyloma in the anus is caused by a virus of human papilloma, marked by the presence of rapidly growing cutaneous verrucae with itching, mild pain and offensive secretion. Diagnosis can be made based on biopsy. The disease is of high recurrence and very difficult to be cured radically. The author combined surgery with external washing with Chinese herbal medicine and achieved quite good results. The following is report of the treatment.

  2. [Effect of aerospace weightlessness on cognitive functions and the relative dialectical analysis of Chinese medicine].

    Science.gov (United States)

    Dong, Li; Liu, Xin-Min; Wu, Li-Sha; Yang, Si-Jin; Wang, Qiong

    2014-03-01

    Aerospace medicine has paid more and more attention to abnormal changes of physiological functions induced by weightlessness and studies on their prevention during space flight. In this paper, the effect of space weightlessness on cognitive functions was introduced. We tried to analyze the correlation between the cognitive function changes and relevant Chinese medical syndromes, thus providing a potential available way to prevent and treat weightlessness induced cognitive deficit during space flight.

  3. Finding Inhibitors of Mutant Superoxide Dismutase-1 for Amyotrophic Lateral Sclerosis Therapy from Traditional Chinese Medicine

    OpenAIRE

    2014-01-01

    Superoxide dismutase type 1 (SOD1) mutations cause protein aggregation and decrease protein stability, which are linked to amyotrophic lateral sclerosis (ALS) disease. This research utilizes the world's largest traditional Chinese medicine (TCM) database to search novel inhibitors of mutant SOD1, and molecular dynamics (MD) simulations were used to analyze the stability of protein that interacted with docked ligands. Docking results show that hesperidin and 2,3,5,4′-tetrahydroxystilbene-2-O- ...

  4. Advances in Experimental Studies on Treatment of Psoriasis by Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    张洪儒; 瞿幸

    2002-01-01

    @@ Psoriasis is a chronic and recurrent dermatosis marked by excessive hyperplasia of epidermal cells. The cause and pathogenesis are unknown. In the last few years, traditional Chinese medicine (TCM) has manifested its strength in treating psoriasis. In order to delve into the mechanism governing the TCM treatment of psoriasis, some clinical and experimental studies were carried out. The following is a review of the advance of the studies since the 1990's.Effects on Proliferation and Differentiation of Keratinocytes (Epithelial Cells)

  5. Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines

    OpenAIRE

    Chai, Stella; To, Kenneth KW; Lin, Ge

    2010-01-01

    Multi-drug resistance (MDR) of cancer cells severely limits therapeutic outcomes. A proposed mechanism for MDR involves the efflux of anti-cancer drugs from cancer cells, primarily mediated by ATP-binding cassette (ABC) membrane transporters including P-glycoprotein. This article reviews the recent progress of using active ingredients, extracts and formulae from Chinese medicine (CM) in circumventing ABC transporters-mediated MDR. Among the ABC transporters, Pgp is the most extensively studie...

  6. In silico identification of anti-cancer compounds and plants from traditional Chinese medicine database

    OpenAIRE

    Shao-Xing Dai; Wen-Xing Li; Fei-Fei Han; Yi-Cheng Guo; Jun-Juan Zheng; Jia-Qian Liu; Qian Wang; Yue-Dong Gao; Gong-Hua Li; Jing-Fei Huang

    2016-01-01

    There is a constant demand to develop new, effective, and affordable anti-cancer drugs. The traditional Chinese medicine (TCM) is a valuable and alternative resource for identifying novel anti-cancer agents. In this study, we aim to identify the anti-cancer compounds and plants from the TCM database by using cheminformatics. We first predicted 5278 anti-cancer compounds from TCM database. The top 346 compounds were highly potent active in the 60 cell lines test. Similarity analysis revealed t...

  7. A Non-Contact Pulse Automatic Positioning Measurement System for Traditional Chinese Medicine

    OpenAIRE

    Ying-Yun Chen; Rong-Seng Chang; Ko-Wen Jwo; Chung-Chi Hsu; Chu-Pang Tsao

    2015-01-01

    This study is to construct a non-contact pulse automatic positioning measurement system for Traditional Chinese Medicine (TCM) using optical triangulation measurements. The system consists of a linear laser, a CMOS image sensor and image analysis software. The linear laser is projected on the pulse beat location on the wrists; the CMOS image sensor records the process and the software analyzes the images. The program mainly uses the optical centroid and fast Fourier transform (FFT) principles...

  8. Huangqi Injection (a Traditional Chinese Patent Medicine) for Chronic Heart Failure: A Systematic Review

    OpenAIRE

    Shufei Fu; Junhua Zhang; Francesca Menniti-Ippolito; Xiumei Gao; Francesca Galeotti; Marco Massari; Limin Hu; Boli Zhang; Rita Ferrelli; Alice Fauci; Fabio Firenzuoli; Hongcai Shang; Ranieri Guerra; Roberto Raschetti

    2011-01-01

    BACKGROUND: Chronic heart failure (CHF) is a global public health problem. Therefore, novel and effective drugs that show few side-effects are needed. Early literature studies indicated that Huangqi injection is one of the most commonly used traditional Chinese patent medicines for CHF in China. As a large number of clinical studies has been carried out and published, it is essential to evaluate the effectiveness and safety of Huangqi injection. Therefore, we carried out this systematic revie...

  9. Regional Influences on Chinese Medicine Education: Comparing Australia and Hong Kong

    OpenAIRE

    Caragh Brosnan; Vincent C. H. Chung; Anthony L. Zhang; Jon Adams

    2016-01-01

    High quality education programs are essential for preparing the next generation of Chinese medicine (CM) practitioners. Currently, training in CM occurs within differing health and education policy contexts. There has been little analysis of the factors influencing the form and status of CM education in different regions. Such a task is important for understanding how CM is evolving internationally and predicting future workforce characteristics. This paper compares the status of CM education...

  10. Determination of vanadium in food and traditional Chinese medicine by graphite furnace atomic absorption spectroscopy

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Various experimental conditions were described for the vanadium determination by graphite furnace atomic ab-sorption spectroscopy (GFAAS). The experiments showed that when atomization took place under the conditions where thecombination of a pyrolytic coating graphite tube and fast raising temperature were used and the temperature was stable, thesignal peak shapes could be improved, the sensitivity was enhanced, and the memory effect was removed. The vanadium infood and traditional Chinese medicinal herbs can be accurately determined using the standard curve method.

  11. Volatile oils of Chinese crude medicines exhibit antiparasitic activity against human Demodex with no adverse effects in vivo

    OpenAIRE

    LIU, JI-XIN; Sun, Yan-Hong; Li, Chao-Pin

    2015-01-01

    Demodex is a type of permanent obligatory parasite, which can be found on the human body surface. Currently, drugs targeting Demodex usually result in adverse effects and have a poor therapeutic effect. Thus, the aim of the present study was to investigate the use of Chinese crude medicine volatile oils for targeting and inhibiting Demodex in vitro. The volatile oils of six Chinese crude medicines were investigated, including clove, orange fruit, Manchurian wildginger, cinnamon bark, Rhizome ...

  12. Mathematical model of biological order state or syndrome in traditional Chinese medicine: based on electromagnetic radiation within the human body.

    Science.gov (United States)

    Han, Jinxiang; Huang, Jinzhao

    2012-03-01

    In this study, based on the resonator model and exciplex model of electromagnetic radiation within the human body, mathematical model of biological order state, also referred to as syndrome in traditional Chinese medicine, was established and expressed as: "Sy = v/ 1n(6I + 1)". This model provides the theoretical foundation for experimental research addressing the order state of living system, especially the quantitative research syndrome in traditional Chinese medicine.

  13. Prospective registration, bias risk and outcome-reporting bias in randomised clinical trials of traditional Chinese medicine

    DEFF Research Database (Denmark)

    Liu, Jian-Ping; Han, Mei; Li, Xin-Xue;

    2013-01-01

    Clinical trials on Traditional Chinese Medicine (TCM) should be registered in a publicly accessible international trial register and report on all outcomes. We systematically assessed and evaluated TCM trials in registries with their subsequent publications.......Clinical trials on Traditional Chinese Medicine (TCM) should be registered in a publicly accessible international trial register and report on all outcomes. We systematically assessed and evaluated TCM trials in registries with their subsequent publications....

  14. The teacher-disciple tradition and secret teaching in Chinese medicine.

    Science.gov (United States)

    Solos, Ioannis; Liang, Yuan; Yue, Guang-xin

    2014-01-01

    The ancient teacher-disciple tradition is regarded as one of the most celebrated practices within the Chinese medicine world. Such traditions of secrecy, private wisdom and honor are deeply rooted in the theories of Confucianism. This paper only explores the surface of this ancient culture, by investigating relevant popular ancient texts and common Chinese proverbs, as well as utilizing personal experiences, in order to reflect on how the ancient Chinese perceived such practices within their own society and how secret teaching was passed on from teacher to student, including the revelation of secret formulas and their importance and how that tradition differs from our modern-day perspectives. Various rare manuscripts from the author's personal library are employed in order to provide relative examples of the importance of secret knowledge, and how these secrets applied in the traditional healing. PMID:24126973

  15. [Geraldo Horácio de Paula Souza, China and Chinese medicine, 1928-1943].

    Science.gov (United States)

    Roland, Maria Inês de França; Gianini, Reinaldo José

    2013-01-01

    This essay is on the writings of sanitary doctor Geraldo Horácio de Paula Souza in Eugenia e Imigração (1928) and, after an official trip to the Orient, in Digressões sobre a medicina chinesa clássica (1942) and A sabedoria chinesa diante da ciência ocidental e a Escola Médica de Pequim (1943). The documents, analyzed according to the conceptual approach of Carlo Ginzburg, indicate a change in his view of the Chinese. Trained according to the Rockefeller Foundation's model of experimental medicine, Geraldo de Paula Souza was guided in his work by scientific rigor and record imagery. In his youth he was of the opinion that the Chinese civilization was stagnated, but this view changed after his visit, when he perceived the Chinese republic's capacity to modernize. PMID:24141921

  16. Multiscale Inorganic Hierarchically Materials: Towards an Improved Orthopaedic Regenerative Medicine.

    Science.gov (United States)

    Ruso, Juan M; Sartuqui, Javier; Messina, Paula V

    2015-01-01

    Bone is a biologically and structurally sophisticated multifunctional tissue. It dynamically responds to biochemical, mechanical and electrical clues by remodelling itself and accordingly the maximum strength and toughness are along the lines of the greatest applied stress. The challenge is to develop an orthopaedic biomaterial that imitates the micro- and nano-structural elements and compositions of bone to locally match the properties of the host tissue resulting in a biologically fixed implant. Looking for the ideal implant, the convergence of life and materials sciences occurs. Researchers in many different fields apply their expertise to improve implantable devices and regenerative medicine. Materials of all kinds, but especially hierarchical nano-materials, are being exploited. The application of nano-materials with hierarchical design to calcified tissue reconstructive medicine involve intricate systems including scaffolds with multifaceted shapes that provides temporary mechanical function; materials with nano-topography modifications that guarantee their integration to tissues and that possesses functionalized surfaces to transport biologic factors to stimulate tissue growth in a controlled, safe, and rapid manner. Furthermore materials that should degrade on a timeline coordinated to the time that takes the tissues regrow, are prepared. These implantable devices are multifunctional and for its construction they involve the use of precise strategically techniques together with specific material manufacturing processes that can be integrated to achieve in the design, the required multifunctionality. For such reasons, even though the idea of displacement from synthetic implants and tissue grafts to regenerative-medicine-based tissue reconstruction has been guaranteed for well over a decade, the reality has yet to emerge. In this paper, we examine the recent approaches to create enhanced bioactive materials. Their design and manufacturing procedures as well

  17. [Exploration of research approaches of Chinese medicine's pharmacology based on "imprinting templates" (medical element) of supramolecules].

    Science.gov (United States)

    He, Fu-yuan; He, Hong; Deng, Kai-wen; Zhou, Yi-qun; Shi, Ji-lian; Liu, Wen-long; Yang, Yan-tao; Tang, Yu

    2015-11-01

    The paper, based on the previous publication as special impact of Chinese medicine theories on supramolcular chemistry, aims to analyze the natural origination for the Chinese medicine and to explain the special impact of "Qi chromatography" reaction on "imprinting templates" in supramolcular host of human being with Chinese medicine, in order to reveal the CM's properties of "medical element" with "imprinting templates" autonomisation generally took place in natural supramolecules, and also to discover that the CM's pharmacology are satisfied with its own approaches different form western pharmacology. It was decided, for CM's pharmacology guided by CM's theories, to "Qi chromatography" relations between the CM's ingredient groups and the meridian zang-fu viscera. The supramolcular chemistry played an all-through role in procession of making macro-regularities and special presentation on behavior of "Qi chromatography" impulse owning to the matching action of all kinds of ingredients on the meridian zang-fu viscera with similar "imprinting templates". The CM's pharmacology were guided by CM's theories, owing to its interpretation of supramolecular chemistry. The pharmacology was achieved to construct up completely on base of classical chemical single molecular bonds whereas the CM's pharmacology be configured to big building by way of "imprinting templates" as multi-weak bonds among "supramolecular society". CM's pharmacology was supramolcular pharmacology dealt with "molecular society" on the base of western pharmacology, and employed to double research approaches both math-physical quantitative representation on macroscope and qualitative analyses in microscope.

  18. Traceability and Quality Control in Traditional Chinese Medicine: From Chemical Fingerprint to Two-Dimensional Barcode

    Directory of Open Access Journals (Sweden)

    Yong Cai

    2015-01-01

    Full Text Available Chemical fingerprinting is currently a widely used tool that enables rapid and accurate quality evaluation of Traditional Chinese Medicine (TCM. However, chemical fingerprints are not amenable to information storage, recognition, and retrieval, which limit their use in Chinese medicine traceability. In this study, samples of three kinds of Chinese medicines were randomly selected and chemical fingerprints were then constructed by using high performance liquid chromatography. Based on chemical data, the process of converting the TCM chemical fingerprint into two-dimensional code is presented; preprocess and filtering algorithm are also proposed aiming at standardizing the large amount of original raw data. In order to know which type of two-dimensional code (2D is suitable for storing data of chemical fingerprints, current popular types of 2D codes are analyzed and compared. Results show that QR Code is suitable for recording the TCM chemical fingerprint. The fingerprint information of TCM can be converted into data format that can be stored as 2D code for traceability and quality control.

  19. Classification of Mixtures of Chinese Herbal Medicines Based on a Self-organizing Map (SOM).

    Science.gov (United States)

    Wang, Maolin; Li, Li; Yu, Changyuan; Yan, Aixia; Zhao, Zhongzhen; Zhang, Ge; Jiang, Miao; Lu, Aiping; Gasteiger, Johann

    2016-04-01

    Chinese Herbal Medicines (CHMs) are typically mixtures of compounds and are often categorized into cold and hot according to the theory of Chinese Medicine. This classification is essential for guiding the clinical application of CHMs. In this study, three types of molecular descriptors were used to build models for classification of 59 CHMs with typical cold/hot properties in the training set taken from the original records on properties in China Pharmacopeia as reference. The accuracy and the Matthews correlation coefficient of the models were validated by a test set containing other 56 CHMs. The best model produced the accuracies of 94.92 % and 83.93 % on training set and test set, respectively. The MACCS fingerprint model is robust in predicting hot/cold properties of the CHMs from their major constituting compounds. This work shows how a classification model for data consisting of multi-components can be developed. The derived model can be used for the application of Chinese herbal medicines. PMID:27491920

  20. Literature review and analysis of the development of health outcomes assessment instruments in Chinese medicine

    Institute of Scientific and Technical Information of China (English)

    Feng-bin Liu; Zheng-kun Hou; Yun-ying Yang; Zheng-zheng Zhang; Di Xie; Nelson Xie; Hong Thach Nguyen

    2013-01-01

    OBJECTIVE:To evaluate the development of health outcomes assessment instruments in Chinese medicine.METHODS:A comprehensive literature search for all published articles in China National Knowledge Infrastructure Database,Chongqing VIP Database and WANFANG Data was conducted.The studies that met the inclusion and exclusion criteria were used to extract information according to a predesigned assessment instrument.RESULTS:A total of 97 instruments for health outcome assessment in Chinese medicine were identified.Of these questionnaires,7 were generic,12 were condition-specific and 78 were disease-specific.All instruments were suitable for adults,children,and both men and women.These instruments aimed to evaluate the health-related quality of life,signs and symptoms as well as patient satisfaction and doctor-reported outcome.However,the descriptions were poorly constructed for some of the most basic parameters,such as the domains and items,administrative mode,response options,memory recall periods,burden evaluation,format,copyright,content validity,and other properties.CONCLUSION:The instrument development for health outcomes assessment in Chinese medicine is increasing rapidly; however,there are many limitations in current methodologies and standards,and further studies are needed.

  1. Antitumor effects of traditional Chinese medicine targeting the cellular apoptotic pathway

    Directory of Open Access Journals (Sweden)

    Xu HL

    2015-05-01

    Full Text Available Huanli Xu,1 Xin Zhao,2 Xiaohui Liu,1 Pingxiang Xu,1 Keming Zhang,2 Xiukun Lin11Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, 2Department of Hepatobiliary Surgery, 302 Hospital of Chinese People’s Liberation Army, Beijing, People’s Republic of ChinaAbstract: Defects in apoptosis are common phenomena in many types of cancer and are also a critical step in tumorigenesis. Targeting the apoptotic pathway has been considered an intriguing strategy for cancer therapy. Traditional Chinese medicine (TCM has been used in the People’s Republic of China for thousands of years, and many of the medicines have been confirmed to be effective in the treatment of a number of tumors. With increasing cancer rates worldwide, the antitumor effects of TCMs have attracted more and more attention globally. Many of the TCMs have been shown to have antitumor activity through multiple targets, and apoptosis pathway-related targets have been extensively studied and defined to be promising. This review focuses on several antitumor TCMs, especially those with clinical efficacy, based on their effects on the apoptotic signaling pathway. The problems with and prospects of development of TCMs as anticancer agents are also presented.Keywords: traditional Chinese medicine, antitumor effects, apoptotic pathway

  2. Traditional Chinese medicine "Qing Yi Tang" alleviates oxygen free radical injury in acute necrotizing pancreatitis

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    AIM To observe the changes in oxygen free radical (OFR) and the curative effect of traditional Chinese medicine "Qing Yi Tang" in acute necrotizing pancreatitis (ANP).METHODS After induction of ANP by injection of sodium taurocholate into pancreatic duct, 16 dogs were randomly divided into control group and Chinese medicine group. Serum amylase, SOD and MDA were determined on postoperative day 1, 2, 4 and 7. The animals were sacrificed on day 7. SOD and MDA in organs were determined, and pathological changes in pancreas were observed.RESULTS As compared with control group, the serum level of amylase (734U/L vs 2783U/L) and MDA (7.8nmol/ml vs 14.8nmol/ml) in Chinese medicine group were decreased on day 7 (P<0.05), while SOD increased significantly (281nU/ml vs 55nU/ml, P<0.01), and similar changes occurred in MDA and SOD in organs, especially in the pancreas; the pathological changes in the pancreas were alleviated as well.CONCLUSION "Qing Yi Tang" is effective in clearing OFRs and alleviating pathological changes in ANP.

  3. 中医手法与人类健康%Traditional Chinese Medicine Technique and Human Health

    Institute of Scientific and Technical Information of China (English)

    王之虹

    2012-01-01

    中医手法包括针法、灸法、推拿、整骨、刮痧、拔罐、功法、针刀等中医特色诊疗手法.作用机制为通过皮部—络脉—经脉—脏腑这一由表及里的疾病防治网络,达到疏通经络、行气活血的目的,进而发挥平衡阴阳、调整脏腑的功能.中医手法是调理人体“亚健康”状态最适宜的手段,在人类健康产业的发展中发挥巨大的作用.%Traditional Chinese medicine technique is characteristic of TCM diagnosis and treatment practices, include acupuncture, moxibustion, TuiNa, osteopathy, GuaSha, cupping, exercises, needle knife, etc. It's mechanism of action isthrough the disease prevention network from the outside to the inside, which is skin areas - collaterals - meridians - organs, to clear the meridians and transport qi and blood,and thus play a balance of yin and yang, adjust the function of organs. Traditional Chinese medicine technique is the most appropriate means to condition the human body "sub - healthy" state. Traditional Chinese medicine technique will play a major role in the developmet of the human health industry.

  4. TCM Database@Taiwan: the world's largest traditional Chinese medicine database for drug screening in silico.

    Science.gov (United States)

    Chen, Calvin Yu-Chian

    2011-01-06

    Rapid advancing computational technologies have greatly speeded up the development of computer-aided drug design (CADD). Recently, pharmaceutical companies have increasingly shifted their attentions toward traditional Chinese medicine (TCM) for novel lead compounds. Despite the growing number of studies on TCM, there is no free 3D small molecular structure database of TCM available for virtual screening or molecular simulation. To address this shortcoming, we have constructed TCM Database@Taiwan (http://tcm.cmu.edu.tw/) based on information collected from Chinese medical texts and scientific publications. TCM Database@Taiwan is currently the world's largest non-commercial TCM database. This web-based database contains more than 20,000 pure compounds isolated from 453 TCM ingredients. Both cdx (2D) and Tripos mol2 (3D) formats of each pure compound in the database are available for download and virtual screening. The TCM database includes both simple and advanced web-based query options that can specify search clauses, such as molecular properties, substructures, TCM ingredients, and TCM classification, based on intended drug actions. The TCM database can be easily accessed by all researchers conducting CADD. Over the last eight years, numerous volunteers have devoted their time to analyze TCM ingredients from Chinese medical texts as well as to construct structure files for each isolated compound. We believe that TCM Database@Taiwan will be a milestone on the path towards modernizing traditional Chinese medicine.

  5. Factors associated with utilization of traditional Chinese medicine by white collar foreign workers living in Taiwan

    Directory of Open Access Journals (Sweden)

    Deng Chung-Yeh

    2009-01-01

    Full Text Available Abstract Background Traditional Chinese medicine (TCM has remained an integral part of Chinese culture and society for thousands of years. In Taiwan TCM is a recognized element of its National Health Insurance Scheme. However, there is no knowledge about how TCM is accessed by foreign workers from a non-Asian cultural background. The objectives of this study were to investigate the prevalence and patterns of TCM use among non-Asian white-collar workers living in Taiwan, and examine factors likely to influence their use of TCM. Methods This study applied a cross-sectional survey design. A total of 207 white-collar foreign workers of a non-Asian background currently holding National Health Insurance cards who had lived in Taiwan for 4 months or more participated in this study. Results The prevalence of TCM use was 45%. The most frequently used therapies were traditional Chinese herbs/medicine and acupuncture. Factors indicating the likelihood of TCM usage were age 31–40 years, visit to an allopathic medical doctor in the last year, ability to read Chinese, having a friend or family member available to assist in the use of TCM, and access to information about TCM services available in Taiwan. Conclusion Utilization of TCM by people of a non-Asian background living in Taiwan appears to be most influenced by enabling factors including language ability, access to information, and informal reference persons.

  6. Treatment for intractable anemia with the traditional Chinese medicines Hominis Placenta and Cervi Cornus Colla (deer antler glue

    Directory of Open Access Journals (Sweden)

    Yasuyo Hijikata

    2009-05-01

    Full Text Available Yasuyo Hijikata1, Takashi Kano2, Lu Xi31Toyodo Hijikata Clinic, Osaka, Japan; 2Kano Clinic, Osaka city, Osaka, Japan; 3Traditional Chinese Medicine Institute, Si-chuan Province, ChinaObjective: Intractable anemia, such as aplastic anemia or that presumably associated with chronic herpes virus infections, sometimes require bone marrow transplant. We investigated the use of traditional Chinese medicine (TCM for the treatment of intractable anemia. Method: Placenta Hominis (PH, steam boiled and roasted, and Cervi Cornus Colla (deer antler glue has been used in China for hundreds of years to treat anemia. After consent was obtained, we prescribed these two materials for a 74-year-old female with aplastic anemia and a 26-year-old male with presumably a virus-induced anemia. Concomitant conventional therapy was continued in both patients as prescribed by their respective attending physicians. Conclusion: Conventional therapy with steroid hormones, immunosuppressive drugs, platelet and erythrocyte transfusions were not effective in these patients. In addition, both patients suffered from serious side effects. In two patients, ingestion of Placenta Hominis and Cervi Cornus Colla with TCM prescriptions increased the platelet and enhanced the hemoglobin concentration in several months of therapy accompanied by a dramatic improvement in quality of life. The addition to conventional therapy of PH and Cervi Cornus Colla, the latter of which is very easy to obtain, may be one of the potentially advantageous choices in case of otherwise intractable anemia.Keywords: placenta, antler glue, Cervi Cornus Colla, anemia, aplastic anemia

  7. 中医科学性的再思考%Reconsideration of the Scientific Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    魏睦新; 胡平

    2009-01-01

    Recently, the debates among traditional Chinese medicine and western medicine have never stopped, some people put forward abolishing traditional Chinese medicine or just leaving along Chinese herbs. However tides of opposition had never destroyed traditional Chinese medicine. There must been reasons in it. The deepest reason why traditional Chi-nese medicine can live along lles in its scientific characteristics. So how to develop traditional Chinese medicine should been the point people focus on.%东西方医学的争论近年来从未停止过,有人以"中医不科学"为由,提出废除中医药,或者"废医存药",但一波又一波的反对浪潮从未能摧毁中医,中医之所以能生存下来,必然有其理由.究其内因在于中医是具有科学性的,因此如何发展中医应该是人们重视及研究的焦点.

  8. Methodology guideline for clinical studies investigating traditional Chinese medicine and integrative medicine: executive summary.

    Science.gov (United States)

    Liu, Jian-Ping; Chen, Ke-Ji

    2015-10-01

    This guideline aims to provide a methodological guidance for clinical studies in TCM and integrative medicine in terms of study design, execution, and reporting. The commonly used methods including experimental and observational methods were introduced in this guideline such as randomized clinical trials, cohort study, case-control study, case series, and qualitative method which can be incorporated into above quantitative methods. The guideline can be used for the evaluation of therapeutic effect of TCM therapies or their combination with conventional therapy. TCM therapy refers to one of the followings or their combination: herbal medicine, acupuncture, moxibustion, cupping, Taichi/Qigong, and Guasha,Tuina (therapeutic massage). It is also suitable for research and development of ethnopharmaceuticals or folk medicine.

  9. Effects of combined therapy of traditional Chinese medicine and western medicine on platelets, coagulative functions and inflammatory cytokines with ulcerative colitis

    Institute of Scientific and Technical Information of China (English)

    Yun-Xia Lei; Lei He; Hao Sheng; Xin Liu

    2016-01-01

    Objective:To explore the effects of combined therapy of traditional Chinese medicine and western medicine on platelets, coagulative functions and inflammatory cytokines in patients with ulcerative colitis (UC). Methods:A total of 267 patients with UC were collected. 137 patients were treated with combined therapy of traditional Chinese medicine and western medicine as experimental group and 130 patients were treated with only western medicine as controls. Platelet count, coagulation function indexes and inflammatory cytokines were measured before and 15 d after the treatment. Results:No significantly differences were found in all indexes before treatment between two groups. After different treatments, platelet count (PLT), platelet distribution width (PDW) were significantly decreased in both groups, but mean platelet volumn (MPV) were significantly increased than before treatment. PLT and PDW were significantly lower and MPV were significantly higher in experimental group than control group. Fibrinogen (Fib) and D-dimer (DD) decreased significantly after treatment. Fib and DD in experimental group were significantly lower than controls. No significantly differences were found in activated partial thromboplastin time (APTT) and prothrobin time (PT). Tumor necrosisi factor-α(TNF-α), interleukin-6 (IL-6) and interleukin-8 (IL-8) decreased significantly in both group after treatment. TNF-α, IL-6 and IL-8 were significantly lower in experimental group than controls. Conclusion:Combined therapy of traditional Chinese medicine and western medicine can more effectively improve the cogulation, fibrinolysis and inflammation in patients with UC than only western medicine therapy.

  10. Published the papers of HPLC-MS analysis—Traditional Chinese medicine

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Medicinal materials Ma Chenchen, Li Bailin, Ou Jie, Wang Jing, Zhao Junhong. Detection of N-acyl-homoserine lactones class signal molecules of quorum sensing secreted by bacteria using high performance liquid chromatography-mass spectrometry/ mass spect

  11. Traditional Chinese Medicine and herbal hepatotoxicity: a tabular compilation of reported cases.

    Science.gov (United States)

    Teschke, Rolf; Zhang, Li; Long, Hongzhu; Schwarzenboeck, Alexander; Schmidt-Taenzer, Wolfgang; Genthner, Alexander; Wolff, Albrecht; Frenzel, Christian; Schulze, Johannes; Eickhoff, Axel

    2015-01-01

    Traditional Chinese Medicine (TCM) with its focus on herbal use became popular worldwide. Treatment was perceived as safe, with neglect of rare adverse reactions including liver injury. To compile worldwide cases of liver injury by herbal TCM, we undertook a selective literature search in the PubMed database and searched for the items Traditional Chinese Medicine, TCM, Traditional Asian Medicine, and Traditional Oriental Medicine, also combined with the terms herbal hepatotoxicity or herb induced liver injury. The search focused primarily on English-language case reports, case series, and clinical reviews. We identified reported hepatotoxicity cases in 77 relevant publications with 57 different herbs and herbal mixtures of TCM, which were further analyzed for causality by the Council for International Organizations of Medical Sciences (CIOMS) scale, positive reexposure test results, or both. Causality was established for 28/57 different herbs or herbal mixtures, Bai Xian Pi, Bo He, Ci Wu Jia, Chuan Lian Zi, Da Huang, Gan Cao, Ge Gen, Ho Shou Wu, Huang Qin, Hwang Geun Cho, Ji Gu Cao, Ji Xue Cao, Jin Bu Huan, Jue Ming Zi, Jiguja, Kudzu, Ling Yang Qing Fei Keli, Lu Cha, Rhen Shen, Ma Huang, Shou Wu Pian, Shan Chi, Shen Min, Syo Saiko To, Xiao Chai Hu Tang, Yin Chen Hao, Zexie, and Zhen Chu Cao. In conclusion, this compilation of liver injury cases establishes causality for 28/57 different TCM herbs and herbal mixtures, aiding diagnosis for physicians who care for patients with liver disease possibly related to herbal TCM. PMID:25536637

  12. Selected Terms in Traditional Chinese Medicine and Their Interpretations (XV)

    Institute of Scientific and Technical Information of China (English)

    谢竹藩

    2001-01-01

    @@Febrifugation (清热) (清热) [qing re] or Heat-Clearing Method (清法) [qing fa] One of the principal therapeutic methods by administering medicines cool or cold in nature to treat interior heat. Clearing heat and removing toxin (清热解毒)(清热解毒) [qing re jie du]: a therapeutic method for acute infectious diseases and pyogenic inflammations caused by toxic heat. Clearing Qi heat (清气分热) (清气分热) [qing qi fen re]: a therapeutic method of treating acute febrile disease at the Qi stage, also abbreviated as "clearing the Qi" (清气) (清气) [qing qi]. Clearing Ying heat (清营分热) (清营分热) [qing ying fen re]: a therapeutic method of treating acute febrile disease at the Ying stage, also abbreviated as "clearing the Ying" (清营) (清营) [qing ying]. Clearing Heart fire (清心火) [qing xin huo]: a method to treat exuberant Heart fire, also known as "clearing the Heart" (清心) [qing xin]. Clearing Lung heat (清肺热) (清肺热) [qing fei re]: a method to treat excessive heat in the Lung, also known as "clearing the Lung" (清肺) [qing fei].

  13. The Main Anticancer Bullets of the Chinese Medicinal Herb, Thunder God Vine

    Directory of Open Access Journals (Sweden)

    Zi Liu

    2011-06-01

    Full Text Available The thunder god vine or Tripterygium wilfordii Hook. F. is a representative Chinese medicinal herb which has been used widely and successfully for centuries in treating inflammatory diseases. More than 100 components have been isolated from this plant, and most of them have potent therapeutic efficacy for a variety of autoimmune and inflammatory diseases. In the past four decades, the anticancer activities of the extracts from this medicinal herb have attracted intensive attention by researchers worldwide. The diterpenoid epoxide triptolide and the quinone triterpene celastrol are two important bioactive ingredients that show a divergent therapeutic profile and can perturb multiple signal pathways. Both compounds promise to turn traditional medicines into modern drugs. In this review, we will mainly address the anticancer activities and mechanisms of action of these two agents and briefly describe some other antitumor components of the thunder god vine.

  14. Botanical compounds and their regulation of nuclear receptor action: the case of traditional Chinese medicine.

    Science.gov (United States)

    Li, Ling; Bonneton, François; Chen, Xiao Yong; Laudet, Vincent

    2015-02-01

    Nuclear receptors (NRs) are major pharmacological targets that allow an access to the mechanisms controlling gene regulation. As such, some NRs were identified as biological targets of active compounds contained in herbal remedies found in traditional medicines. We aim here to review this expanding literature by focusing on the informative articles regarding the mechanisms of action of traditional Chinese medicines (TCMs). We exemplified well-characterized TCM action mediated by NR such as steroid receptors (ER, GR, AR), metabolic receptors (PPAR, LXR, FXR, PXR, CAR) and RXR. We also provided, when possible, examples from other traditional medicines. From these, we draw a parallel between TCMs and phytoestrogens or endocrine disrupting chemicals also acting via NR. We define common principle of action and highlight the potential and limits of those compounds. TCMs, by finely tuning physiological reactions in positive and negative manners, could act, in a subtle but efficient way, on NR sensors and their transcriptional network. PMID:25449417

  15. [Prescription rules of Chinese herbal medicines in treatment of gastric cancer].

    Science.gov (United States)

    Cao, Wen; Zhao, Ai-guang

    2009-01-01

    Analysis of the nature, tastes, channel distributions and effects of the frequently used herbal medicines in the prescriptions involved in the clinical literatures about treatment of gastric cancer published from 1988 to 2007 was made in the paper. The literatures were categorized into three types: 1) treatment of middle- and late-stage gastric cancer; 2) prevention and treatment of the recurrence and metastasis after operation; 3) Chinese herbal medicines combined with chemotherapy for enhancing efficacy and reducing toxicity. The most frequently used herbal medicines in the three literature types were qi-invigorating herbs, such as Atractylodes, Astragalus, Codonopsis, Glycyrrhiza and Ginseng, etc. The herbal medicines for promoting urination to subside swelling such as tuckahoe and Semen Coicis, etc were used more frequently than the herbal medicines for regulating qi such as dried orange peel and putchuck, etc, as well as for clearing away heat to remove toxin such as spreading hedyotis herb, Herba Scutellariae Barbatae, yangtao actinidia root, and Rhizoma Paridis, etc. From another angle, the most frequently used herbal medicines for the treatment of gatric cancer were those cold, warm and neutral in nature, sweet, bitter and pungent in taste, and distributed to spleen and liver channels. PMID:19134451

  16. Mechanism of traditional Chinese medicine in the treatment of allergic rhinitis

    Institute of Scientific and Technical Information of China (English)

    GUO Hong; LIU Ming-ping

    2013-01-01

    Objective To review the major progress in mechanism of traditional Chinese medicine (TCM) in the treatment of allergic rhinitis (AR).Methods Contents about the treatment mechanism of TCM in the therapy of AR in this article were obtained from 22 original articles and reviews published in Chinese-and English-language journals.All of the references were searched by use of Pubmed (1997-2012).Results AR is one of the most common and most serious public health problems in children and young people.Many AR patients were worried about the possible adverse effects of synthetic drugs they were taking.Thus,they seek complementary and alternative therapy,such as TCM.TCM emphasized on the importance of holistic convalescence,not just the disease itself.The favorable safety profile of TCM makes well-acceptance by the general population.In the recent decade,more and more studies of TCM for AR are developed.These studies indicated that the treatment of allergic disorders with TCM therapy including herbal medicines and acupuncture are of safety and efficacy.The mechanism of TCM in the treatment of AR has been discussed.It has been reported that a number of the herbs in the Chinese herbal formulae used in the treatment possess anti-allergic,anti-inflammatory or immune modulation activity.Such function include the inhibition of the release or the activity of mast cell mediators (such as histamine),inhibition the induction of inflammation reaction by chemical agents,and down regulation of serum (immunoglobulin E) IgE levels or the activity of lymphocyte and/or macrophage.Conclusions TCM are frequently used concurrently to improve the clinical efficacy.This review is focuses on the description of the actions mechanism of Chinese medicine's approach relevant to the treatment of AR.

  17. 近代中医学校教育的主要特点研究%Educational Characteristics of Chinese Medicine School in Modern Time

    Institute of Scientific and Technical Information of China (English)

    张增国; 张成博

    2011-01-01

    Modern education in Chinese medicine school is an essential component of modem education and modern medicine education in China. During the tortuous development of modern education in Chinese medicine school, some achievements have been obtained and the experiences can be the good reference for the education today of Chinese medicine school. Based on the deep analysis and collection of historical materials,the paper presents several characters of modern education in Chinese medicine school: opening courses of western medicine, emphasizing clinical practice;stressing on teaching material writing, implementing "the interaction of academic journals and education" ;strictly standardizing education, adapting to modern education;rising non - government schools and hard process of development. As compared with master - apprentice system,the modern education in Chinese medicine school is much more advantageous in personnel training, course offering and textbook construction. Through the exploration of the characters and advantages of modem education of Chinese medicine, some outlooks on future education of Chinese medicine are summarized: stressing classics of Chinese medicine, improving teaching pattern, enhancing clinical training, adjusting course offering and developing international exchange. These outlooks may lay the foundation for a further research in the future.%近代中医学校教育是我国近代教育及近代医学教育不可缺少的组成部分.近代中医学校教育在曲折发展的历程中取得了一些成绩,其经验可以为当今的中医学校教育提供有益的借鉴.文章在深入挖掘、搜集、整理史料的基础上,凝炼了近代中医学教育的几个特点:开设西医课程,重视临床实践;重视教材编写,实行"刊学相辅";办学规范严格,适应近代教育;民办学校兴起,发展历程曲折.近代中医学校教育在人才培养、课程设置、教材建设等方面与师承教育相比,有很多优势.通

  18. Treatment of advanced breast cancer with chinese medicinal herbs of Fei decoction: a case report.

    Science.gov (United States)

    Lv, G M; Hu, M; Chen, R Z; Zhu, L L; Tao, Ch J; Xia, X D; Gong, Y L; Li, P; Wan, H J

    2014-01-01

    A 46-year-old female underwent surgery for cancer of the right breast mammary (T3N2M0) in Sep 2010. Following post surgery, adjuvant chemotherapy of CAF regimens (cyclophosphamide+adriamycin+fluorouracil) was administered. Two years later, multiple pulmonary and skeletal metastatic lesions had been found by CT (computerized tomography) and ECT (emission computed tomograph) imaging. She received the treatment of second-line chemotherapy regimens of GP (cisplatin + gemcitabine). In the meantime, we administered Chinese traditional herb drugs (Fei Decoction, mixed a variety of effective herbal components) to help her recover from the poor condition. After taking the Chinese herbs for 2 months, the tumour marker (CEA, CA15-3) dramatically decreased, resulting in the normal range. Both lung and bone metastatic sites reduced according to CT and ECT imaging, and the patient felt free from the complaint of pulmonary and cardiac discomfort. Over time, the quality of life has been greatly improved, we have managed to prolong the PFS (progression-free-survival) and TTP (time-to-progression) from the onset to date. CTM (Chinese traditional medicine) considers human body as a dynamic platform in which all organs are correlative and bind each other. Relationship between heart, liver, spleen, lung and kidney is like an interlink between mother and son, and runs in cycle as a circle. In the course of this combined treatment, we showed that Chinese herbal medicine played an important role in the therapy of breast cancer. Chinese herbs might be an additional choice with their better benefits and tolerability in the treatment of recurrent breast cancer.

  19. Prescriptions of Chinese Herbal Medicines for Insomnia in Taiwan during 2002

    Directory of Open Access Journals (Sweden)

    Fang-Pey Chen

    2011-01-01

    Full Text Available Chinese herbal medicine (CHM has been commonly used for treating insomnia in Asian countries for centuries. The aim of this study was to conduct a large-scale pharmaco-epidemiologic study and evaluate the frequency and patterns of CHM use in treating insomnia. We obtained the traditional Chinese medicine (TCM outpatient claims from the National Health Insurance in Taiwan for the year 2002. Patients with insomnia were identified from the diagnostic code of International Classification of Disease among claimed visiting files. Corresponding prescription files were analyzed, and an association rule was applied to evaluate the co-prescription of CHM. Results showed that there were 16 134 subjects who visited TCM clinics for insomnia in Taiwan during 2002 and received a total of 29 801 CHM prescriptions. Subjects between 40 and 49 years of age comprised the largest number of those treated (25.3%. In addition, female subjects used CHMs for insomnia more frequently than male subjects (female : male = 1.94 : 1. There was an average of 4.8 items prescribed in the form of either an individual Chinese herb or formula in a single CHM prescription for insomnia. Shou-wu-teng (Polygonum multiflorum was the most commonly prescribed single Chinese herb, while Suan-zao-ren-tang was the most commonly prescribed Chinese herbal formula. According to the association rule, the most commonly prescribed CHM drug combination was Suan-zao-ren-tang plus Long-dan-xie-gan-tang, while the most commonly prescribed triple drug combination was Suan-zao-ren-tang, Albizia julibrissin, and P. multiflorum. Nevertheless, further clinical trials are needed to evaluate the efficacy and safety of these CHMs for treating insomnia.

  20. Significance of Evidence-based Medicine in the Assessment of Chinese Medicine Clinical Efficacy

    Institute of Scientific and Technical Information of China (English)

    WANG Ji-yao

    2010-01-01

    @@ Evidence-based medicine (EBM) requires the integration of the best research evidence with our clinical expertise and our patient's unique values and circumstances.The best evidence is valid and clinically relevant,especially from patient-centered clinical research.The clinical expertise means the ability to use our clinical skills and past experiences to rapidly identify each patient's unique health state and diagnosis,their individual risks,and the benefits of interventions (1)..

  1. Effect of integrated traditional Chinese and Western medicine on SARS:A review of clinical evidence

    Institute of Scientific and Technical Information of China (English)

    Ming-Ming Zhang; Xue-Mei Liu; Lin He

    2004-01-01

    AIM: To assess the possible effect of integrated traditional Chinese and Western medicine on severe acute respiratory syndromes.METHODS: The current available randomized controlled trials of integrated traditional Chinese and Western medicine on SARS were identified through systematically searching literature in any languages or any types of publications.Additional studies of gray literature were also collected.The quality of studies was evaluated by two investigators independently based largely on the quality criteria specified CONSORT. Statistical analysis of the results was performed using RevMan 4.2.0 software developed by the Cochrane Collaboration.RESULTS: Six studies (n = 366) fulfilling the inclusion criteria were found, of which the quality of one study was graded as B, the remaining five were graded as C. Two studies were performed with meta-analysis, the other four studies existed some heterogeneity for which meta-analysis could not be performed, a significant effect on lung infiltrate absorption was found in the treatment groups of these two studies [RR 6.68, 95% CI (2.93, 15.24), P<0.01], there was no significant differences between the mortality [RR 0.86, 95%CI (0.22, 3.29), P = 0.82] and the average dosage of corticosteroid [WMD -39.65, 95% CI (-116.84, 37.54),P = 0.31]. The other three studies also showed significant differences in infiltrate absorption, including national drug No. 2. 3.4 in combination with Western medicine [RR 5.45,95% CI (1.54, 19.26)], compound formulas NO. 1 combined with Western medicine [WMD 0.24, 95% CI (0.02, 0.46)],compound formulas combined with Western medicine [RR 8.06, 95% CI (0.40, 163.21)]. Kangfeidian No.4 in combination with Western medicine had no significant effect on symptom improvement such as loss of dyspnea and cough [RR 1.50,95%CI (0.41, 5.43)] and [RR 1.29, 95%CI (0.30, 5.43)].CONCLUSION: Integrated traditional Chinese and Western medicines has some positive effects on lung infiltrate absorption in SARS

  2. [Establishment of three-dimensional integrated "serum pharmacochemistry-pharmacokinetics (pharmacodynamics)-systems biology" for research of traditional Chinese medicine prescription and its application in Yinchenhao Tang].

    Science.gov (United States)

    Zhang, Ai-Hua; Sun, Hui; Yan, Guang-Li; Han, Ying; Wang, Xi-Jun

    2013-11-01

    Traditional Chinese medicine (TCM) prescription is a valuable asset for clinical medication, has multi-component and multi-target characteristics. However, due to the complex ingredients of prescription, the unclear mechanism, the lack of scientific data to support the dose-response relationship, it has become the bottleneck for the in-depth study for the process of modernization and internationalization of TCM. It requires the integration of Chinese medicine theory, modern analysis and data mining technology to build new research model for characteristic of TCM prescription. This paper provides an overview of TCM serum pharmacochemistry, pharmacokinetics (pharmacodynamics) and systems biology theory and practice, to establish the integrated three-dimensional "serum pharmacochemistry-pharmacokinetics (pharmacodynamics)-systems biology" for the research of TCM prescription to reveal the pharma-material basis and action mechanism and the compatibility scientific connotation, with a prescription Yinchenhao Tang as a case study.

  3. [Establishment of three-dimensional integrated "serum pharmacochemistry-pharmacokinetics (pharmacodynamics)-systems biology" for research of traditional Chinese medicine prescription and its application in Yinchenhao Tang].

    Science.gov (United States)

    Zhang, Ai-Hua; Sun, Hui; Yan, Guang-Li; Han, Ying; Wang, Xi-Jun

    2013-11-01

    Traditional Chinese medicine (TCM) prescription is a valuable asset for clinical medication, has multi-component and multi-target characteristics. However, due to the complex ingredients of prescription, the unclear mechanism, the lack of scientific data to support the dose-response relationship, it has become the bottleneck for the in-depth study for the process of modernization and internationalization of TCM. It requires the integration of Chinese medicine theory, modern analysis and data mining technology to build new research model for characteristic of TCM prescription. This paper provides an overview of TCM serum pharmacochemistry, pharmacokinetics (pharmacodynamics) and systems biology theory and practice, to establish the integrated three-dimensional "serum pharmacochemistry-pharmacokinetics (pharmacodynamics)-systems biology" for the research of TCM prescription to reveal the pharma-material basis and action mechanism and the compatibility scientific connotation, with a prescription Yinchenhao Tang as a case study. PMID:24494574

  4. Effect of powdered activated carbon on Chinese traditional medicine wastewater treatment in submerged membrane bioreactor with electronic control backwashing

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Chinese traditional medicine wastewater,rich in macromolecule and easy to foam in aerobic biodegradation such as Glycosides.was treated by two identical bench-scale aerobic submerged membrane bioreactors (SMBRs) operated in parallel under the same feed,equipped with the same electronic control backwashing device.One was used as the control SMBR (CSMBR) while the other was dosed with powdered activated carbon (PAC)(PAC-amended SMBR,PSMBR).The backwashing interval was 5 min.One suction period was about 90 min by adjusting preestablished backwashing vacuum and pump frequency.The average flux of CSMBR during a steady periodic state of 24 d (576 h) was 5.87 L/h with average hydraulic residence time (HRT) of 5.97h and that of PSMBR during a steady periodic state of 30 d (720 h) was 5.85 L/h with average HRT of 5.99 h.The average total chemical oxygen demand (COD) removal wastewater effluent standard GB8978-1996 for the raw medicine material industry (300 mg/L).Hence,SMBR with electronic control backwashing was a viable process for medium- strength Chinese traditional medicine wastewater treatment.Moreover,the increasing rates of preestablished backwashing vacuum,pump frequency,and vacuum and flux loss caused by mixed liquor in PSMBR all lagged compared to those in CSMBR:thus the actual operating time of the PSMBR system without membrane cleaning was extended by up to 1.25 times in contrast with the CSMBR system,and the average total COD removal efficieney of PSMBR was enhanced with higher average OLR.

  5. Evaluation of Chinese medicine Qian-Yu for chronic bacterial prostatitis in rats

    Directory of Open Access Journals (Sweden)

    Jinhu Wu

    2011-01-01

    Full Text Available Objectives : Qian-Yu (QY, a Chinese medicine formula, has anti-inflammatory and broad spectrum anti-bacterial activity. This study is undertaken to evaluate the anti-inflammatory effects of Qian-Yu (QY in chronic bacterial prostatitis (CBP. Materials and Methods : The potential of QY in the treatment of CBP was evaluated using a CBP animal model by examining the anti-inflammatory activity. Its consequences were analyzed by immunological and histopathological methods. Experimental chronic bacterial prostatitis was induced by instillation of bacterial suspension of Escherichia coli 7.5 ΄ 10 5 CFU/ml into the prostatic urethra. Animals were followed up for four weeks and then treated with either 7 mg/kg QY or 7 mg/kg positive control agent-Qianlietai (QLT or 1 ml of phosphate-buffered saline (PBS for the controls. Ten rats in each group were sacrificed at the end of four weeks. The inhibition of inflammation and its consequences were analyzed histologically. Prostatic IL-8, SIgA and zinc concentrations were measured by ELISA, RIA and ICP-AES, respectively. The data was expressed as mean ± S.D. Least-significant difference (LSD of one-way ANOVA (SPSS 12.0 was used to determine the differences of scores. Results : The histopathology showed resolving prostatitis in QY-and QLT-treated groups and the immunology showed reduction of IL-8 and increment of SIgA contents in prostatic tissues as compared to the control groups. The prostatic zinc levels were higher in the QY-and QLT-treated groups than those in the controls. These results suggested that QY is effective in CBP treatment.

  6. Enhanced stability and antibacterial efficacy of a traditional Chinese medicine-mediated silver nanoparticle delivery system

    Directory of Open Access Journals (Sweden)

    Sun WJ

    2014-11-01

    Full Text Available Wenjie Sun,1,2,* Ding Qu,1,* Yihua Ma,1 Yan Chen,1,2 Congyan Liu,1 Jing Zhou11Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, 2Department of Pharmaceutics, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, People’s Republic of China*These authors contributed equally to this workAbstract: Silver nanoparticles (AgNPs are widely used as antibacterial products in various fields. Recent studies have suggested that AgNPs need an appropriate stabilizer to improve their stability. Some antibacterial traditional Chinese medicines (TCMs contain various reductive components, which can not only stabilize AgNPs but also enhance their antimicrobial activity. In this study, we developed a series of novel AgNPs using a TCM extract as a stabilizer, reducing agent, and antimicrobial agent (TCM-AgNPs. A storage stability investigation of the TCM-AgNPs suggested a significant improvement when compared with bare AgNPs. Further, conjugation of TCMs onto the AgNP surface resulted in stronger antimicrobial potency on antibacterial evaluation using Pseudomonas aeruginosa, Staphylococcus epidermidis, and Staphylococcus aureus with minimum inhibitory concentration 50% (MIC50 ratios (and minimum bactericidal concentration 90% [MBC90] ratios of AgNPs to respective TCM-AgNPs as assessment indices. Among these, P. cuspidatum Sieb. et-conjugated AgNPs (P.C.-AgNPs had the advantage of a combination of TCMs and AgNPs and was studied in detail with regard to its synthesis and characterization. The extraction time, reaction temperature, and concentrations of AgNO3 and Polygonum cuspidatum Sieb. et extract were critical factors in the preparation of P.C.-AgNPs. Further, the results of X-ray diffraction and Fourier transform infrared spectroscopy indicated successful preparation of P.C.-AgNPs. In representative studies, P.C.-AgNPs showed a well-defined spherical shape, a homogeneous

  7. [The motive characteristics and pattern of manifestation of Chinese medicinal herb during the period of "Cultural Revolution"].

    Science.gov (United States)

    Zhang, Wei; Zhang, Rui-xian

    2009-01-01

    During the period of "Cultural Revolution", there started a movement of Chinese medicinal herb throughout the whole country. As a national movement meeting the needs of the time, not only had the guarantee of national policy, but also had the support of finance and the propaganda of People's Daily, PLA Daily and Red Flag Magazine. The movement had all kinds of different manifestations such as cooperative medical care, mobile medical team, research team, three tu (folk recipe, folk healer, folk medicine), four selves (self-planting, self-collection, self-making, self-use), exhibition of Chinese medicinal herb, compiling the handbook of Chinese medicinal herb etc. It had reference values to the current medical care system. PMID:19824359

  8. 中药有效成分分析现状%Analysis Current Situation of Chinese Medicine Effective Ingredients

    Institute of Scientific and Technical Information of China (English)

    富波; 宗可昕; 孟鑫; 陈忠新; 范卓文

    2015-01-01

    Traditional Chinese medicine is Chinese traditional characteristic medicine. In recent years, it has been recognized and applied by more and more countries. Therefore, the research and development of Traditional Chinese medicine has aroused wide-spread attention at home and abroad more and more. Traditional Chinese medicine has wide varieties, and the composition is complex. The analysis of Traditional Chinese medicine effective ingredients has become an important research content. Various analysis meth-ods and instruments have been used in the field of Traditional Chinese medicine. In this paper, the analysis method of effective ingre-dients of Traditional Chinese medicine was reviewed, expounding its characteristics, the scope of application and the research status.%中药是中国的传统特色药材,近年来,被越来越多的国家所承认和应用。因此,中药的研发也越来越受到国内外的普遍重视。中药品种繁多,成分复杂,中药有效成分的分析就成为了一项重要的研究内容,各种分析方法和仪器在中药领域得到运用,本文对中药有效成分分析的方法进行了综述,阐述了其特点、应用范围及研究现状。

  9. 中药组分与组分生物药剂学分类系统构建%Traditional Chinese medicine components and construction of components biopharmaceutical classification system

    Institute of Scientific and Technical Information of China (English)

    刘丹; 郁丹红; 孙娥; 贾晓斌

    2012-01-01

    中药复方物质基础是多组分,在研究中药生物药剂学性质时,应该以组分为研究对象.针对中药多组分生物药剂学研究,该文提出科学代表中药组分综合性质的有限成分的选择思路;其次,引入“离散度”的概念,以考察组分中各代表性成分个体性质之间的差异,从而更科学全面地评价中药组分的性质;最终结合组分综合性质值及离散度,初步构建中药组分生物药剂学分类系统,为中药多组分生物药剂学性质研究提出新的思路与方法.%Traditional Chinese medicine compound of material base is multi-components. It should be divided into groups to study traditional Chinese medicine biopharmaceutical properties. To study traditional Chinese medicine multi-component biopharmaceu-tical, this paper puts forward the scientific representative Chinese medicine integrated nature of the components of the composition, choose ideas. Secondly, this paper introduces the concept of " discrete degree" to examine difference about representative nature of each component. It should be more comprehensive evaluation of traditional Chinese medicine scientific nature of the components. With the comprehensive property value final components and discrete degrees, setting up a part of traditional Chinese medicine biopharmaceutical classification system, traditional Chinese medicine for the multi-composition biopharmaceutical nature study puts forward a new way and method.

  10. Traditional Chinese Medicine Prescriptions Enhance Growth Performance of Heat Stressed Beef Cattle by Relieving Heat Stress Responses and Increasing Apparent Nutrient Digestibility

    OpenAIRE

    Song, Xiaozhen; Luo, Junrong; Fu, Daibo; Zhao, Xianghui; Bunlue, Kornmatitsuk; Xu, Zhensong; Qu, Mingren

    2014-01-01

    The present aim was to investigate the effects of traditional Chinese medicine prescriptions (TCM) on body temperature, blood physiological parameters, nutrient apparent digestibility and growth performance of beef cattle under heat stress conditions. Twenty-seven beef cattle were randomly divided into three groups as following; i) high temperature control (HTC), ii) traditional Chinese medicine prescriptions I+high temperature (TCM I) and iii) traditional Chinese medicine prescriptions II+hi...

  11. On Integration of Traditional Chinese Medicine and Western Medicine from the Perspective of Syncretism%融贯论视域下的中西医结合

    Institute of Scientific and Technical Information of China (English)

    马家忠; 张洪雷

    2012-01-01

    融贯论是对中医整体综合方法和西医分析还原方法的扬弃,是一种适合于中西医结合的方法论.在融贯论的视域下,中西医结合必须坚持时间结构和空间结构相统一、整体综合和分析还原相融合、随机治疗和规范治疗相补充、实践行动和认识理解相配合,才能更好地促进中西医结合医学的发展.%Syncretism is the sublation of Traditional Chinese Medicine macroscopic integration and Western Medicine micro-analysis, and it is a kind of methodology suiting for integrated Traditional Chinese and Western Medicine. From the angle of Syncretism, integrated Traditional Chinese and Western Medicine has to persist in the unification of time structure and space structure, the fusion of macroscopic integration and micro-analysis, the supplement of random cure and standard cure, the combination of cognition and practice. Only in the way can we promote the development of integrated Traditional Chinese and Western Medicine.

  12. 腹痛的中医内科治疗分析%Analysis of Traditional Chinese Medicine Treatment of Abdominal Pain in Department of Internal Medicine

    Institute of Scientific and Technical Information of China (English)

    靖春梅

    2015-01-01

    Objective Study on the abdominal pain’s treatment by the method of Internal Medicine of Traditional Chinese Medicine. Methods Analyse the sixty cases of patients’ abdominal pain treatment datum who were treated by the method of Traditional Chinese Medicine in January,2012 to June, 2014. Results We can treat the patient as abdominal pain’s initial diagnosis when the disease cannot be determined, and conduct a series of dialectical treatments. Conclusion Now, I will analyse the methods that treat abdominal pain with Traditional Chinese Medicine,such as dialectical prescription, Chinese patent medicine, effective medical prescription, diet therapy, acupuncture and other methods.%目的:探讨腹痛的中医内科治疗方法。方法对2012年1月~2014年6月收治的腹痛患者60例中医治疗资料进行分析。结果腹痛的病种尚不能确定时,可以腹痛待查作为初步诊断,并进行辨证论治。结论现对中医治疗腹痛方法中辨证组方、中成药、单方验方、饮食疗法、针灸等方法进行分析。

  13. Three Important Links of Internal Medicine of Traditional Chinese Medicine%学习《中医内科学》重要的"三个环节"

    Institute of Scientific and Technical Information of China (English)

    考希良

    2012-01-01

    According to teaching characteristics and requirements of the curriculum Internal Medicine of Traditional Chinese Medicine, and teaching and learning experience of the author, for a beginner of Internal Medicine of Traditional Chinese Medicine, one must skillfully memorize basic concepts of diseases, understand disease pathogenesis, and able to identify syndrome types.%根据课程的教学特点和要求,作者结合自己教学工作和学习体会,对的学习方法进行了个人经验总结.分别从强调疾病基本概念的熟练记忆、理解掌握疾病的病因病机、证型记忆要融会贯通三个环节进行了经验凝练,以期对初学者有一个较好的指导或者指引作用.

  14. Emerging Glycolysis Targeting and Drug Discovery from Chinese Medicine in Cancer Therapy

    Directory of Open Access Journals (Sweden)

    Zhiyu Wang

    2012-01-01

    Full Text Available Molecular-targeted therapy has been developed for cancer chemoprevention and treatment. Cancer cells have different metabolic properties from normal cells. Normal cells mostly rely upon the process of mitochondrial oxidative phosphorylation to produce energy whereas cancer cells have developed an altered metabolism that allows them to sustain higher proliferation rates. Cancer cells could predominantly produce energy by glycolysis even in the presence of oxygen. This alternative metabolic characteristic is known as the “Warburg Effect.” Although the exact mechanisms underlying the Warburg effect are unclear, recent progress indicates that glycolytic pathway of cancer cells could be a critical target for drug discovery. With a long history in cancer treatment, traditional Chinese medicine (TCM is recognized as a valuable source for seeking bioactive anticancer compounds. A great progress has been made to identify active compounds from herbal medicine targeting on glycolysis for cancer treatment. Herein, we provide an overall picture of the current understanding of the molecular targets in the cancer glycolytic pathway and reviewed active compounds from Chinese herbal medicine with the potentials to inhibit the metabolic targets for cancer treatment. Combination of TCM with conventional therapies will provide an attractive strategy for improving clinical outcome in cancer treatment.

  15. Natural Products from Chinese Medicines with Potential Benefits to Bone Health.

    Science.gov (United States)

    Che, Chun-Tao; Wong, Man Sau; Lam, Christopher Wai Kei

    2016-01-01

    Osteoporosis is a progressive, systemic bone disorder characterized by loss of bone mass and microstructure, leading to reduced bone strength and increased risk of fracture. It is often associated with reduced quality of life and other medical complications. The disease is common in the aging population, particularly among postmenopausal women and patients who receive long-term steroidal therapy. Given the rapid growth of the aging population, increasing life expectancy, the prevalence of bone loss, and financial burden to the healthcare system and individuals, demand for new therapeutic agents and nutritional supplements for the management and promotion of bone health is pressing. With the advent of global interest in complementary and alternative medicine and natural products, Chinese medicine serves as a viable source to offer benefits for the improvement and maintenance of bone health. This review summarizes the scientific information obtained from recent literatures on the chemical ingredients of Chinese medicinal plants that have been reported to possess osteoprotective and related properties in cell-based and/or animal models. Some of these natural products (or their derivatives) may become promising leads for development into dietary supplements or therapeutic drugs. PMID:26927052

  16. Natural Products from Chinese Medicines with Potential Benefits to Bone Health

    Directory of Open Access Journals (Sweden)

    Chun-Tao Che

    2016-02-01

    Full Text Available Osteoporosis is a progressive, systemic bone disorder characterized by loss of bone mass and microstructure, leading to reduced bone strength and increased risk of fracture. It is often associated with reduced quality of life and other medical complications. The disease is common in the aging population, particularly among postmenopausal women and patients who receive long-term steroidal therapy. Given the rapid growth of the aging population, increasing life expectancy, the prevalence of bone loss, and financial burden to the healthcare system and individuals, demand for new therapeutic agents and nutritional supplements for the management and promotion of bone health is pressing. With the advent of global interest in complementary and alternative medicine and natural products, Chinese medicine serves as a viable source to offer benefits for the improvement and maintenance of bone health. This review summarizes the scientific information obtained from recent literatures on the chemical ingredients of Chinese medicinal plants that have been reported to possess osteoprotective and related properties in cell-based and/or animal models. Some of these natural products (or their derivatives may become promising leads for development into dietary supplements or therapeutic drugs.

  17. Simultaneous Determination of Nine Active Compounds of the Traditional Chinese Medicinal Prescription Shaoyao-Gancao-Tang and Analysis of the Relationship between Therapeutical Effect and Compatibility of Medicines

    OpenAIRE

    Guangwei Zhu; Guijun Zhang; Meng Wang; Jingjuan Wang; Weixin Zeng; Xiaomei Gao

    2014-01-01

    A simple and sensitive HPLC-DAD detection method was established for the simultaneous determination of nine compounds including oxypaeoniflorin, albiflorin, paeoniflorin, benzoylpaeoniflorin, glycyrrhizic acid, liquiritin, isoliquiritin, liquiritigenin, and isoliquiritigenin in the Traditional Chinese Medicinal Prescription Shaoyao-Gancao-Tang (SGT) and we analyze the relationship between therapeutical effect and compatibility of medicines by using an Agilent extend-C18 column at a flow rate ...

  18. Cancer survivors’ perspectives and experience on western medicine and traditional Chinese medicine treatment and rehabilitation: a qualitative study

    Science.gov (United States)

    Wang, Ji-Wei; Yang, Zhi-Qi; Liu, Cong; Chen, Si-Jia; Shen, Qian; Zhang, Tian-Rui; Partike, Nancy S; Yuan, Zheng-Ping; Yu, Jin-Ming

    2015-01-01

    Background In the People’s Republic of China, both western medicine (WM) and traditional Chinese medicine (TCM) are the main treatment and rehabilitation options for cancer patients. This study aimed to explore cancer survivors’ perspectives and experience of treatment and rehabilitation, in order to promote patient-centered activities of treatment and rehabilitation. Methods Using a qualitative research approach, 68 cancer survivors were recruited from eight community cancer rehabilitation organizations in Shanghai, People’s Republic of China. Eight focus group interviews were conducted. All these interviews were transcribed verbatim, and the data were analyzed by theme analysis. Results WM was the main choice in treatment phase though study participants noted more side effects. TCM was primarily used in the recovery phase. The lack of communication between doctors and cancer patients appears to affect treatment adherence and impair the doctor–patient relationship. WM was expensive for diagnostic procedures and treatment, while the cumulative costs of frequent use of TCM in the long rehabilitation period were also high. Both treatment options created significant perceived economic burden on patients. Conflicting information about dietary supplements tended to make cancer survivors confused. Conclusion Improving the communication between doctors and cancer patients helps to ameliorate cancer patient adherence and the effect of treatments. It is essential to educate cancer patients about the effect and cost of both WM and traditional TCM. Meanwhile, marketing management and guidance to consumers regarding use of dietary supplements in the cancer rehabilitation field are also necessary. PMID:25565779

  19. Anti-Inflammatory Effects of 81 Chinese Herb Extracts and Their Correlation with the Characteristics of Traditional Chinese Medicine

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    Chang-Liang Chen

    2014-01-01

    Full Text Available Inducible nitrogen oxide synthase (iNOS is the primary contributor of the overproduction of nitric oxide and its inhibitors have been actively sought as effective anti-inflammatory agents. In this study, we prepared 70% ethanol extracts from 81 Chinese herbs. These extracts were subsequently evaluated for their effect on nitrogen oxide (NO production and cell growth in LPS/IFNγ-costimulated and unstimulated murine macrophage RAW264.7 cells by Griess reaction and MTT assay. Extracts of Daphne genkwa Sieb.et Zucc, Caesalpinia sappan L., Iles pubescens Hook.et Arn, Forsythia suspensa (Thunb. Vahl, Zingiber officinale Rosc, Inula japonica Thunb., and Ligusticum chuanxiong Hort markedly inhibited NO production (inhibition > 90% at 100 μg/mL. Among active extracts (inhibition > 50% at 100 μg/mL, Rubia cordifolia L., Glycyrrhiza glabra L., Iles pubescens Hook.et Arn, Nigella glandulifera Freyn et Sint, Pueraria lobata (Willd. Ohwi, and Scutellaria barbata D. Don displayed no cytotoxicity to unstimulated RAW246.7 cells while increasing the growth of LPS/IFNγ-costimulated cells. By analyzing the correlation between their activities and their Traditional Chinese Medicine (TCM characteristics, herbs with pungent flavor displayed potent anti-inflammatory capability. Our study provides a series of potential anti-inflammatory herbs and suggests that herbs with pungent flavor are candidates of effective anti-inflammatory agents.

  20. New Perspectives on Chinese Herbal Medicine (Zhong-Yao Research and Development

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    Si-Yuan Pan

    2011-01-01

    Full Text Available Synthetic chemical drugs, while being efficacious in the clinical management of many diseases, are often associated with undesirable side effects in patients. It is now clear that the need of therapeutic intervention in many clinical conditions cannot be satisfactorily met by synthetic chemical drugs. Since the research and development of new chemical drugs remain time-consuming, capital-intensive and risky, much effort has been put in the search for alternative routes for drug discovery in China. This narrative review illustrates various approaches to the research and drug discovery in Chinese herbal medicine. Although this article focuses on Chinese traditional drugs, it is also conducive to the development of other traditional remedies and innovative drug discovery.

  1. Herba Cistanche (Rou Cong-Rong: One of the Best Pharmaceutical Gifts of Traditional Chinese Medicine

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    Zhiming eLi

    2016-03-01

    Full Text Available Cistanche species, known as Rou Cong-Rong in Chinese, are an endangered wild species and are mainly distributed in the arid lands and warm deserts of northwestern China. Within Traditional Chinese Medicine (TCM, Herba Cistanche is applied as a tonic and/or in a formula for chronic renal disease, impotence, female infertility, morbid leucorrhea, profuse metrorrhagia and senile constipation. The chemical constituents of Herba Cistanche mainly consist of volatile oils, non-volatile phenylethanoid glycosides (PhGs, iridoids, lignans, alditols, oligosaccharides and polysaccharides. There have been an increasing number of studies focusing on its bio-activities, including antioxidation, neuroprotection, and antiaging. The objective of this review is to introduce this herb to the world. Its taxonomy, distribution, and corresponding biological functions and molecular mechanisms are addressed in this review.

  2. Herba Cistanche (Rou Cong-Rong): One of the Best Pharmaceutical Gifts of Traditional Chinese Medicine.

    Science.gov (United States)

    Li, Zhiming; Lin, Huinuan; Gu, Long; Gao, Jingwen; Tzeng, Chi-Meng

    2016-01-01

    Cistanche species, known as Rou Cong-Rong in Chinese, are an endangered wild species and are mainly distributed in the arid lands and warm deserts of northwestern China. Within Traditional Chinese Medicine (TCM), Herba Cistanche is applied as a tonic and/or in a formula for chronic renal disease, impotence, female infertility, morbid leucorrhea, profuse metrorrhagia, and senile constipation. The chemical constituents of Herba Cistanche mainly consist of volatile oils, non-volatile phenylethanoid glycosides (PhGs), iridoids, lignans, alditols, oligosaccharides, and polysaccharides. There have been an increasing number of studies focusing on its bio-activities, including antioxidation, neuroprotection, and antiaging. The objective of this review is to introduce this herb to the world. Its taxonomy, distribution, and corresponding biological functions and molecular mechanisms are addressed in this review. PMID:26973528

  3. New Perspectives on Chinese Herbal Medicine (Zhong-Yao) Research and Development

    Science.gov (United States)

    Pan, Si-Yuan; Chen, Si-Bao; Dong, Hong-Guang; Yu, Zhi-Ling; Dong, Ji-Cui; Long, Zhi-Xian; Fong, Wang-Fun; Han, Yi-Fan; Ko, Kam-Ming

    2011-01-01

    Synthetic chemical drugs, while being efficacious in the clinical management of many diseases, are often associated with undesirable side effects in patients. It is now clear that the need of therapeutic intervention in many clinical conditions cannot be satisfactorily met by synthetic chemical drugs. Since the research and development of new chemical drugs remain time-consuming, capital-intensive and risky, much effort has been put in the search for alternative routes for drug discovery in China. This narrative review illustrates various approaches to the research and drug discovery in Chinese herbal medicine. Although this article focuses on Chinese traditional drugs, it is also conducive to the development of other traditional remedies and innovative drug discovery. PMID:21785622

  4. Intervention effect of traditional Chinese medicine Yi Tang Kang on metabolic syndrome of spleen deficiency

    Institute of Scientific and Technical Information of China (English)

    Xiao-Xi Liu; Yan Shi

    2015-01-01

    Objective:To investigate effects of herbal compoundYiTangKang on the spleen deficiency metabolic syndrome.Methods:Forty maleWistar rats were randomly divided into two groups: the normal control group and theMS spleen deficiency syndrome group.The control group rats were fed with standard diet and water, whileMS spleen deficiency syndrome group with high fat diet and low dose intraperitoneal injection ofstreptozocin, which swam to the endurance limit. After12 weeks, theMS spleen deficiency syndrome group was randomly divided into two groups, with13 rats in each group.Rats in model group were fed with high fat diet and continuouly administered with daily saline, and rats in intervention group with high fat diet were trated with traditionalChinese medicinesYiTangKang by gavage,2 mL/200 g at the same time every day.10 weeks later, the expression of serum proteomics was investigated through abdominal aortic puncture and separation of serum, using isotope labeling technique, high performance liquid chromatography and four bar-Orbitrap mass spectrometer.Results:After treatment with traditionalChinese medicine yitangkang, in the model group, important carboxylesterase and retinal guanylatecyclase2 precursor were upregulated.As for intervention group, these indesxes were raised, but immunoglobulinIgG, carnitine acetyltransferase, tubulin beta -5, andGanLu sugar binding proteinC were down-regulated.At the same time, some new biological active substances, such as protein tyrosine kinase, beta glucosidase were also found.Conclusions:TraditionalChinese medicinesYiTangKang could regulate glucose and lipid metabolism in rats with spleen deficiency syndrome.

  5. The Great Significance of Establishing Strategic Status of Traditional Chinese Medicine (TCM)

    Institute of Scientific and Technical Information of China (English)

    JiaQian; ChengYongjie; ChengGuangman; YangJuping; YingGuangrong

    2005-01-01

    Traditional Chinese Medicine(TCM), based on the philosophic idea of “correlation between man and nature” and “balance of Yin and Yang” and characterized by “integrated concept” and “syndrome identification & treatment determination”, adjusts and activates the self-recuperating ability to rectify its differentiation from normality of human body to meet the goal of preventing and treating diseases mainly by means of traditional Chinese medicinal herbs, acupuncture and moxibustion, etc. The idea of “Human should be in harmony with Nature including bacterium, virus, etc., but not to extemainate microbe in a large scale”, held and promoted by TCM gives, rise to a delicate physiological equilibrium kept between man and microbe and this is just the development trend of medical science in future. For thousands years, TCM has made indelible contribution to the reproduction and prosperity of the Chinese nation, and under the countless attacks of pestilence has never made its people's death in millions, not such as once occurred in Europe. TCM is also characterized by its “simple, convenient, cheap and effective” method of treatment and is especially good at preventing and treating chronic diseases,complicate multi-system diseases and new-type virus diseases. Therefore, only when the sanitation and healthcare system is established can the health of 1.3 billion people in China and the problem of shoaage of doctor and medicine for 900 million rural population and large number of poverty-stricken urban population be solved. It is strongly suggested that five promotion projects, namely: TCM policy and statute guarantee, TCM qualified personnel cultivation, TCM scientific research, development of TCM in rural areas and TCM administrative system reform should be carried out in real earnest to make TCM develop in a sustainable way.

  6. Study on the mechanism of regulation on peritoneal lymphatic stomata with Chinese herbal medicine

    Institute of Scientific and Technical Information of China (English)

    Shi-Ping Ding; Ji-Cheng Li; Jian Xu; Lian-Gen Mao

    2002-01-01

    AIM: To study the mechanism of Chinese herbal medicine(CHM), the prescription consists of Radix SalviaeMiltiorrhizae , Radix Codonopsitis Pilosulae , RhizornaAtractylodis Alba and Rhizoma Alismatis, LeonurusHeterophyllus Sweet, etc ) on the regulation of theperitoneal lymphatic stomata and the ascites drainage.METHODS: The mouse model of live fibrosis wasestablished with the application of intragastric installationsof carbon tetrachloride once every three days; scanningelectron microscope and computer image processing wereused to detect the area and the distributive density of theperitoneal lymphatic stomata; and the concentrations ofurinary ion and NO in the serum were measured analyzed inthe experiment.RESULTS: Two different doses of CHM could significantlyincrease the area of the peritoneal lymphatic stomata,promote its distribution density and enhance the arainage ofurinary ion such as sodium, potassium and chlorine.Meanwhile, the NO concentration of two different doses ofCHM groups was 133.52 ± 23.57μmol/L, and 137.2 ±26.79μnol/L respectively. In comparison with the controland model groups ( 48.36 ± 6.83μmol/L, and 35.22 ±8.94μmol/L, P < 0.01 ), there existed significantly markeddifference, this made it clear that Chinese herbal medicinecould induce high endogenous NO concentration. The effectof Chinese herbal medicine on the peritoneal lymphaticstomata and the drainage of urinary ion was altered byadding NO donor (sodium nitropurruside, SNP) or NOsynthase (NOS) inhibitor (N(G)-monomethyl-L-arginine, L-NMMA) to the peritoneal cavity.CONCLUSION: There existed correlations between high NOconcentration and enlargement of the peritoneal lymphaticstomata, which result in enhanced drainage of ascites.These data supported the hypothesis that Chinese herbalmedicine could regulate the peritoneal lymphatic stomata byaccelerating the synthesis and release of endogenous NO.

  7. Desired Chinese medicine practitioner capabilities and professional development needs: a survey of registered practitioners in Victoria, Australia

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    Radloff Alex

    2008-01-01

    Full Text Available Abstract Background The State of Victoria in Australia introduced Chinese medicine practitioner registration in 2000 and issued its education guidelines in late 2002 for introduction in 2005. This study obtained practitioners' views on desired capabilities for competent Chinese medicine practice and to identify professional development needs. Methods A questionnaire, consisting of 28 predefined capabilities in four categories with a rating scale of importance from one to five, was developed and sent to all registered Chinese medicine practitioners in the State of Victoria, Australia in October, 2005. Results Two hundreds and twenty eight completed questionnaires were returned which represented a response rate of 32.5%. Of the four categories of capabilities, technical capabilities were considered to be the most important for clinical practice. Specifically, the ability to perform acupuncture treatment and/or dispense an herbal prescription was ranked the highest. In contrast, research and information management capabilities were considered the least important. The educational background of practitioners appeared to be an important factor influencing their rating of capabilities. Significantly, nearly double the number of practitioners with Australian qualifications than practitioners trained overseas valued communication as an important capability. For continuing professional education, clinical skills courses were considered as a priority while research degree studies were not. Conclusion Registered Chinese medicine practitioners viewed skills training as important but did not support the need for research and information management training. This represents a significant hurdle to developing Chinese medicine as a form of evidence-based healthcare.

  8. Advances in mesenchymal stem cells combined with traditional Chinese medicine therapy for liver fibrosis

    Institute of Scientific and Technical Information of China (English)

    Shu Dong; Shi-bing Su

    2014-01-01

    Liver fibrosis is a primary cause of liver cirrhosis, and even hepatocarcinoma. Recently, the usage of mesenchymal stem cells (MSCs) has been investigated to improve liver ifbrosis. It has been reported that the differentiation, proliferation and migration of MSCs can be regulated by traditional Chinese medicine treatment;however, the mechanisms are still unclear. In this article, the authors review the characteristics of MSCs such as multidirectional differentiation and homing, and its application in animal experiments and clinical trials. The authors also list areas that need further investigation, and look at the future prospects of clinical application of MSCs.

  9. A review of potential harmful interactions between anticoagulant/antiplatelet agents and Chinese herbal medicines.

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    Hsin-Hui Tsai

    Full Text Available BACKGROUND: The risks attributed to drug-herb interactions, even when known, are often ignored or underestimated, especially for those involving anti-clotting drugs and Chinese medicines. The aim of this study was to structurally search and evaluate the existing evidence-based data associated with potential drug interactions between anticoagulant/antiplatelet drugs and Chinese herbal medicines (CHMs and evaluate the documented mechanisms, consequences, and/or severity of interactions. METHODOLOGY AND FINDINGS: Information related to anticoagulant/antiplatelet drug-CHM interactions was retrieved from eight interaction-based textbooks, four web resources and available primary biomedical literature. The primary literature searches were conducted in English and/or Chinese from January 2000 through December 2011 using the secondary databases (e.g., PubMed, Airiti Library, China Journal full-text database. The search terms included the corresponding medical subject headings and key words. Herbs or natural products not used as a single entity CHM or in Chinese Medicinal Prescriptions were excluded from further review. The corresponding mechanisms and severity ratings of interactions were retrieved using MicroMedex®, Lexicomp® and Natural Medicines Comprehensive Database®. Finally, we found 90 single entity CHMs contributed to 306 documented drug-CHM interactions. A total of 194 (63.4% interactions were verified for its evidence describing possible mechanisms and severity. Of them, 155 interactions (79.9% were attributable to pharmacodynamic interactions, and almost all were rated as moderate to severe interactions. The major consequences of these interactions were increased bleeding risks due to the additive anticoagulant or antiplatelet effects of the CHMs, specifically danshen, dong quai, ginger, ginkgo, licorice, and turmeric. CONCLUSIONS/SIGNIFICANCE: Conventional anticoagulants and antiplatelet drugs were documented to have harmful interactions

  10. Effects of Chinese herbal medicine on plasma glucose, protein and energy metabolism in sheep

    Institute of Scientific and Technical Information of China (English)

    Xi Liang; Kyota Yamazaki; Mohammad Kamruzzaman; Xue Bi; Arvinda Panthee; Hiroaki Sano

    2014-01-01

    Background:The use of antibiotics in animal diets is facing negative feedback due to the hidden danger of drug residues to human health. Traditional Chinese herbal medicine has been used to replace antibiotics in the past two decades and played an increasingly important role in livestock production. The present study was carried out to assess the feeding effects of a traditional nourishing Chinese herbal medicine mixture on kinetics of plasma glucose, protein and energy metabolism in sheep. Ruminal fermentation characteristics were also determined. Methods:Four sheep were fed on either mixed hay (MH-diet) or MH-diet supplemented with 2%of Chinese herbal medicine (mixture of Astragalus root, Angelica root and Atractylodes rhizome;CHM-diet) over two 35-day periods using a crossover design. The turnover rate of plasma glucose was measured with an isotope dilution method using [U-13C]glucose. The rates of plasma leucine turnover and leucine oxidation, whole body protein synthesis (WBPS) and metabolic heat production were measured using the [1-13C]leucine dilution and open circuit calorimetry. Results:Body weight gain of sheep was higher (P=0.03) for CHM-diet than for MH-diet. Rumen pH was lower (P=0.02), concentration of rumen total volatile fatty acid tended to be higher (P=0.05) and acetate was higher (P=0.04) for CHM-diet than for MH-diet. Turnover rates of plasma glucose and leucine did not differ between diets. Oxidation rate of leucine tended to be higher (P=0.06) for CHM-diet than for MH-diet, but the WBPS did not differ between diets. Metabolic heat production tended to be greater (P=0.05) for CHM-diet than for MH-diet. Conclusions:The sheep fed on CHM-diet had a higher body weight gain and showed positive impacts on rumen fermentation and energy metabolism without resulting in any adverse response. Therefore, these results suggested that the Chinese herbal medicine mixture should be considered as a potential feed additive for sheep.

  11. [Research on establishment of clinical safety intensive hospital monitoring net of traditional Chinese medicine injection].

    Science.gov (United States)

    Wang, Lian-Xin; Xie, Yan-Ming; Wang, Zhi-Fei

    2012-09-01

    The establishment of clinical safety monitoring net of traditional Chinese medicine (TCM) injection is the one of the key issues of the monitoring work. The monitoring net is including varieties of types of net, such as clinical monitoring net, multimedia network platform, the net of experts or talents. The paper will introduce the establishing method of clinical safety monitoring net, the establishing of clinical safety monitoring net, and the establishing of network based on the internet, the knowledge network construction of experts, the net construction of talents are all included, to assure the development for clinical safety monitoring work.

  12. Significant reduction of sperm disomy in six men: effect of traditional Chinese medicine?

    Institute of Scientific and Technical Information of China (English)

    Helen G. Tempest; Sheryl T. Homa; Xiao-Ping Zhai; Darren K. Griffin

    2005-01-01

    Aim: To test the hypothesis that levels of sperm disomy fell significantly in six men treated by traditional Chinese medicine (TCM). Methods: Fluorescence in situ hybridization (FISH) was done on the sperm heads of six men before and during treatment by TCM. Results: There was a significant reduction in sperm disomy in all six men.This coincided with TCM treatment. Conclusion: This is the first study reporting a significant reduction in sperm disomy in men over a given time course. The fact that this coincided with TCM treatment is intriguing but no conclusions can be drawn from this until placebo-controlled clinical trials are implemented.

  13. Recent Progresses in Analysis of Tongue Manifestation for Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    WEI Bao-guo; CAI Yi-heng; ZHANG Xin-feng; SHEN Lan-sun

    2005-01-01

    Tongue diagnosis is one of the most precious and widely used diagnostic methods in Traditional Chinese Medicine (TCM). However, due to its subjective, qualitative and experience-dependent nature, the studies on tongue characterization have been widely emphasized. This paper surveys recent progresses in analysis of tongue manifestation. These new developments include the cross-network and cross-media color reproduction of tongue image, the automatic segmentation of tongue body based on knowledge, the automatic analysis of curdiness and griminess for the tongue fur and the automatic analysis of plumpness, wryness and dot -thorn of tongue body. The clinic experiments verify the validity of these new methods.

  14. Relationship between Various Chinese Medicine Types and T-cell Subsets in Patients with Ulcerative Colitis

    Institute of Scientific and Technical Information of China (English)

    常廷民; 李秀敏; 赵习德

    2009-01-01

    Objective:To investigate the relationship between various Chinese medicine(CM) types and T-cell subsets(CD4~+ and CD8~+) in the colonic mucous membranes of patients with ulcerative colitis(UC).Methods: Fifty UC patients were enrolled,after differentiation into four types by CM syndromes,i.e.,the internal heat-damp accumulation type(IHDA),the qi-stagnancy with blood stasis type(QSBS),the Pi(脾)-Shen(肾) yang-deficiency type(PSYD) and the yin-blood deficiency type(YBD).From every patient,3-5 pieces of intest...

  15. Discrimination and feature selection of geographic origins of traditional Chinese medicine herbs with NIR spectroscopy

    Institute of Scientific and Technical Information of China (English)

    LIU Shuhua; ZHANG Xuegong; SUN Suqin

    2005-01-01

    With the traditional Chinese medicine herbs angelicae dahuricae radix (ADR or Baizhi) and salviae miltiorrhizae radix (SMR or Danshen) as two examples, this work studies the automatic discrimination of the geographic origins of the herbs using near infrared (NIR) reflectance spectroscopy. Multi-class support vector machine (SVM) is utilized for the purpose, and recursive SVM is utilized to select the feature spectral segments that are decisive for the discrimination. With only 5 and 8 short spectral segments, discriminative accuracies of 92% are achieved on independent test sample sets. This work not only provides a prototype of accurate rapid discriminating systems for quality control of herbal medicines, but also opens new possibilities in studying subtle differences in the chemical compositions of herbs from different cultivation conditions and investigating their associations with the effectiveness of the herbs.

  16. Research advances on the usage of traditional Chinese medicine for neuroprotection in glaucoma

    Institute of Scientific and Technical Information of China (English)

    Xue-song Mi; Jing-xiang Zhong; Raymond Chuen-Chung Chang; Kwok-Fai So

    2013-01-01

    Progressive loss of retinal ganglion cells (RGCs) and their axons is the main pathogenesis of glaucoma.The cause of glaucoma is not fully understood,but the neurodegeneration of glaucoma involves many mechanisms such as oxidative stress,glutamate toxicity and ischemia/reperfusion insult.In order to target these mechanisms,multiple neuroprotective interventions have been investigated to prevent the death of RGCs.Of note are some tonic herbs from the traditional Chinese medicine (TCM) pharmacopeia that have shown neuroprotective effects in glaucoma.TCM differs from Western medicine in that TCM exhibits complicated bioactive components,triggering many signaling pathways and extensive actions on vital organs.Modern scientific approaches have demonstrated some of their underlying mechanisms.In this review,we used Lycium barbarum and Ginkgo biloba as examples to elaborate the characteristics of TCM and their potential applications in neuroprotection in glaucoma.

  17. Arsenic speciation in Chinese Herbal Medicines and human health implication for inorganic arsenic.

    Science.gov (United States)

    Liu, Xiao-Juan; Zhao, Quan-Li; Sun, Guo-Xin; Williams, Paul; Lu, Xiu-Jun; Cai, Jing-Zhu; Liu, Wen-Ju

    2013-01-01

    Rice and drinking water are recognized as the dominant sources of arsenic (As) for human intake, while little is known about As accumulation and speciation in Chinese Herbal Medicines (CHMs), which have been available for many hundreds of years for the treatment of diseases in both eastern and western cultures. Inorganic arsenic was the predominant species in all of CHMs samples. The levels of inorganic arsenic in CHMs from fields and markets or pharmacies ranged from 63 to 550 ng/g with a mean of 208 ng/g and 94 to 8683 ng/g with a mean of 1092 ng/g, respectively. The highest concentration was found in the Chrysanthemum from pharmacies. It indicates that the risk of inorganic As in CHMs to human health is higher in medicines from markets or pharmacies than that collected directly from fields. Some CHMs may make a considerable contribution to the human intake of inorganic arsenic.

  18. A DNA microarray for the authentication of toxic traditional Chinese medicinal plants.

    Science.gov (United States)

    Carles, Maria; Cheung, Matthew Kin; Moganti, Shanti; Dong, Tina T; Tsim, Karl W; Ip, Nancy Y; Sucher, Nikolaus J

    2005-06-01

    A silicon-based DNA microarray was designed and fabricated for the identification of toxic traditional Chinese medicinal plants. Species-specific oligonucleotide probes were derived from the 5S ribosomal RNA gene of Aconitum carmichaeli, A. kusnezoffi, Alocasia macrorrhiza, Croton tiglium, Datura inoxia, D. metel, D. tatula, Dysosma pleiantha, Dy. versipellis, Euphorbia kansui, Hyoscyamus niger, Pinellia cordata, P. pedatisecta, P. ternata, Rhododendron molle, Strychnos nux-vomica, Typhonium divaricatum and T. giganteum and the leucine transfer RNA gene of Aconitum pendulum and Stellera chamaejasme. The probes were immobilized via dithiol linkage on a silicon chip. Genomic target sequences were amplified and fluorescently labeled by asymmetric polymerase chain reaction. Multiple toxic plant species were identified by parallel genotyping. Chip-based authentication of medicinal plants may be useful as inexpensive and rapid tool for quality control and safety monitoring of herbal pharmaceuticals and neutraceuticals. PMID:15971136

  19. The Role of Traditional Chinese Medicine in the Management of Chronic Pain: A Biopsychosocial Approach

    Directory of Open Access Journals (Sweden)

    John Burns

    2015-11-01

    Full Text Available The National Institute of Medicine revealed that chronic pain affects more than 100 million adults in the United States, citing chronic pain as the leading reason patients seek medical care. Pain is also an extremely costly problem, with $635 billion per year spent nationally, more than cancer, heart disease and diabetes combined. The biomedical model of chronic pain management has largely revolved around the use of narcotic analgesics for pain control. Unfortunately, this corresponds to a growth in the rate of abuse, misuse and overdose of these drugs. Additionally, there is an inherent failure rate to the myriad procedures used to control pain, such as spinal epidural injections and insertion of indwelling narcotic delivery systems, largely because these procedures fail to comprehensively address the multiple facets of pain generation. With its roots in the biopsychosocial model of pain management, traditional Chinese medicine may be a useful systematic or adjunct approach in the management of chronic pain.

  20. [Liu Yue-heng and Shengcaoyaoxingfangpu (Guidebook of Chinese medicinal herbal properties)].

    Science.gov (United States)

    Zhang, Lu-Li

    2010-09-01

    Liu Yue-heng, a famous doctor in Hunan province during Qing dynasty is the author of Shengcaoyaoxingfangpu (Guidebook of Chinese medicinal herbs) which systematically summed up the properties, flavors and channel tropism of the local herbal medicines and supplemented a lack knowledge of those. The book collected broadly folk and proved prescriptions and, combined with the author's clinical experiences. He collected and classified them as chapters, reflected geographical environment and folk custom culture with the distinctive regional characteristics of Huxiang. Its achievement is mainly embodied in the following aspects: it attached importance to herbs, highlighted Huxiang characteristics, the skilful use of folk and proved prescriptions and comprehensively differentiated etiology and pathogenesis, and proposed for doctors' professional ethics. PMID:21163083