WorldWideScience

Sample records for childhood geographical analysis

  1. The influence of geographical and economic factors in estimates of childhood abuse and neglect using the Childhood Trauma Questionnaire: A worldwide meta-regression analysis.

    Science.gov (United States)

    Viola, Thiago Wendt; Salum, Giovanni Abrahão; Kluwe-Schiavon, Bruno; Sanvicente-Vieira, Breno; Levandowski, Mateus Luz; Grassi-Oliveira, Rodrigo

    2016-01-01

    This multilevel meta-analysis examined the effects of geographical and economic factors on worldwide childhood maltreatment estimates measured by the Childhood Trauma Questionnaire (CTQ) short-form. The primary outcome extracted was continuous scores on the CTQ subscales - emotional abuse, physical abuse, sexual abuse, emotional neglect, and physical neglect - and total score. Geographical, economical and methodological variables were extracted for use as covariates in meta-regression models. A literature search identified 288 studies suitable for the CTQ total score analysis (N=59,692) and 189 studies suitable for maltreatment subtype analysis (N=44,832). We found that Europe and Asia were associated with lower CTQ estimates while South America presented the highest estimates among continents. Specifically, studies from China, Netherlands and United Kingdom presented the lowest maltreatment estimates. Furthermore, high-income countries presented lower CTQ physical neglect estimates in comparison to low- or middle-income countries, while per-capita gross domestic product of countries was negatively associated with childhood physical neglect estimates. Despite the influence of methodological covariates, these findings indicate that geographical and economic factors could influence variations of childhood maltreatment estimates around the world, particularly when assessed by a structured standardized questionnaire.

  2. Childhood Vitamin A Capsule Supplementation Coverage in Nigeria: A Multilevel Analysis of Geographic and Socioeconomic Inequities

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    Olatunde Aremu

    2010-01-01

    Full Text Available Vitamin A deficiency (VAD is a huge public health burden among preschool-aged children in sub-Saharan Africa, and is associated with a high level of susceptibility to infectious diseases and pediatric blindness. We examined the Nigerian national vitamin A capsule (VAC supplementation program, a short-term cost-effective intervention for prevention of VAD-associated morbidity for equity in terms of socioeconomic and geographic coverage. Using the most current, nationally representative data from the 2008 Nigerian Demographic and Health Survey, we applied multilevel regression analysis on 19,555 children nested within 888 communities across the six regions of Nigeria. The results indicate that there was variability in uptake of VAC supplement among the children, which could be attributed to several characteristics at individual, household, and community levels. Individual-level characteristics, such as maternal occupation, were shown to be associated with receipt of VAC supplement. The results also reveal that household wealth status is the only household-level characteristic that is significantly associated with receipt of VAC, while neighborhood socioeconomic disadvantage and geographic location were the community-level characteristics that determined receipt of VAC. The findings from this study have shown that both individual and contextual socioeconomic status, together with geographic location, is important for uptake of VAC. These findings underscore the need to accord the VAC supplementation program the much needed priority with focus on characteristics of neighborhoods (communities, in addition to individual-level characteristics.

  3. Childhood vitamin A capsule supplementation coverage in Nigeria: a multilevel analysis of geographic and socioeconomic inequities.

    Science.gov (United States)

    Aremu, Olatunde; Lawoko, Stephen; Dalal, Koustuv

    2010-10-01

    Vitamin A deficiency (VAD) is a huge public health burden among preschool-aged children in sub-Saharan Africa, and is associated with a high level of susceptibility to infectious diseases and pediatric blindness. We examined the Nigerian national vitamin A capsule (VAC) supplementation program, a short-term cost-effective intervention for prevention of VAD-associated morbidity for equity in terms of socioeconomic and geographic coverage. Using the most current, nationally representative data from the 2008 Nigerian Demographic and Health Survey, we applied multilevel regression analysis on 19,555 children nested within 888 communities across the six regions of Nigeria. The results indicate that there was variability in uptake of VAC supplement among the children, which could be attributed to several characteristics at individual, household, and community levels. Individual-level characteristics, such as maternal occupation, were shown to be associated with receipt of VAC supplement. The results also reveal that household wealth status is the only household-level characteristic that is significantly associated with receipt of VAC, while neighborhood socioeconomic disadvantage and geographic location were the community-level characteristics that determined receipt of VAC. The findings from this study have shown that both individual and contextual socioeconomic status, together with geographic location, is important for uptake of VAC. These findings underscore the need to accord the VAC supplementation program the much needed priority with focus on characteristics of neighborhoods (communities), in addition to individual-level characteristics.

  4. Childhood Vitamin A Capsule Supplementation Coverage in Nigeria: A Multilevel Analysis of Geographic and Socioeconomic Inequities

    OpenAIRE

    Olatunde Aremu; Stephen Lawoko; Koustuv Dalal

    2010-01-01

    Vitamin A deficiency (VAD) is a huge public health burden among preschool-aged children in sub-Saharan Africa, and is associated with a high level of susceptibility to infectious diseases and pediatric blindness. We examined the Nigerian national vitamin A capsule (VAC) supplementation program, a short-term cost-effective intervention for prevention of VAD-associated morbidity for equity in terms of socioeconomic and geographic coverage. Using the most current, nationally representative data ...

  5. Using a geographic information system to improve childhood lead-screening efforts.

    Science.gov (United States)

    Graff, Robert

    2013-06-13

    The Idaho Division of Public Health conducted a pilot study to produce a lead-exposure-risk map to help local and state agencies better target childhood lead-screening efforts. Priority lead-screening areas, at the block group level, were created by using county tax assessor data and geographic information system software. A series of maps were produced, indicating childhood lead-screening prevalence in areas in which there was high potential for exposure to lead. These maps could enable development of more systematically targeted and cost-effective childhood lead-screening efforts.

  6. Modeling uncertainty in geographic information and analysis

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Uncertainty modeling and data quality for spatial data and spatial analyses are im-portant topics in geographic information science together with space and time in geography,as well as spatial analysis. In the past two decades,a lot of efforts have been made to research the uncertainty modeling for spatial data and analyses. This paper presents our work in the research. In particular,four progresses in the re-search are given out: (a) from determinedness-to uncertainty-based representation of geographic objects in GIS; (b) from uncertainty modeling for static data to dy-namic spatial analyses; (c) from modeling uncertainty for spatial data to models; and (d) from error descriptions to quality control for spatial data.

  7. Geographical and ecological analyses of childhood acute leukaemias and lymphomas in north-west England.

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    McNally, Richard J Q; Alston, Robert D; Cairns, Donal P; Eden, Osborn B; Birch, Jillian M

    2003-10-01

    Childhood leukaemias and lymphomas have been associated with exposure to environmental factors, including infections, which show geographical variation. This study examined the geographical distribution of the incidence of acute leukaemia and lymphoma using Manchester Children's Tumour Registry (MCTR) data 1976-2000. A total of 910 children were included, all of whom had histologically and/or cytologically verified leukaemia or lymphoma. At the time of their diagnoses, all the children were aged 0-14 years and were resident in the counties of Greater Manchester or Lancashire. Standardized morbidity ratios were calculated. Poisson regression was used to examine the relationship between incidence rates and small-area (census ward) population density, ethnic composition and deprivation index. There was a monotonic relationship between acute lymphoblastic leukaemia (ALL) incidence and population density (P = 0.05). Higher rates were seen in more densely populated areas. There was evidence for a monotonic relationship between the incidence of the mixed cellularity subtype of Hodgkin's disease (HD) and the Townsend deprivation score (P = 0.001). Markedly higher incidence was associated with greater levels of unemployment and household overcrowding. The results for ALL and mixed cellularity HD support the involvement of environmental factors, such as infections, in disease aetiology.

  8. THE ENCOUNTER OF KNOWLEDGE: among children, childhoods and ways of seeing and living the geographic space

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    Andressa Farias Vidal

    2015-06-01

    Full Text Available This work is part of an undergraduate research course of pedagogy, entitled "Territorialities of Children in Early Childhood Education Institutions" in the field of Geography of Childhood. This research has been developed in a Municipal Unit of Child Education (UMEI of Niterói, and aims to understand how the small child appropriates the geographical space and from his experience the reframes, showing subjectivities and interpretations of space offered. Whereas the childhoods are located as categories in social structures, the work seeks to reflect on the relationship that children have with the spaces, to the extent that these are mediated by their cultural and social interactions. Thus, in order to observe and interpret the experience of children, this research aims to study the relationships established by them from the triad society, childhood and school in order to understand the social construction of the current childhood and the school's role in modernity. Thus, the research intends to identify how geography analytical categories emerge in the context of games and children's actions in space-times of early childhood education, and with qualitative data enabled by participant observation, erect parameters of being-being of children in space immediate education and its mediation with the world. O presente trabalho é parte de uma pesquisa de iniciação científica do curso de pedagogia, intitulada “Territorialidades de Crianças nas Instituições de Educação Infantil”, no campo da Geografia da Infância. Esta pesquisa vem sendo desenvolvida em uma Unidade Municipal de Educação Infantil (UMEI de Niterói, e tem como objetivo compreender como a criança pequena apropria-se do espaço geográfico e a partir de sua vivência o ressignifica, evidenciando subjetividades e interpretações do espaço ofertado. Considerando que as infâncias se situam como categorias nas estruturas sociais, o trabalho busca refletir sobre as rela

  9. A Framework for Geographic Object-Based Image Analysis (GEOBIA) based on geographic ontology

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    Gu, H. Y.; Li, H. T.; Yan, L.; Lu, X. J.

    2015-06-01

    GEOBIA (Geographic Object-Based Image Analysis) is not only a hot topic of current remote sensing and geographical research. It is believed to be a paradigm in remote sensing and GIScience. The lack of a systematic approach designed to conceptualize and formalize the class definitions makes GEOBIA a highly subjective and difficult method to reproduce. This paper aims to put forward a framework for GEOBIA based on geographic ontology theory, which could implement "Geographic entities - Image objects - Geographic objects" true reappearance. It consists of three steps, first, geographical entities are described by geographic ontology, second, semantic network model is built based on OWL(ontology web language), at last, geographical objects are classified with decision rule or other classifiers. A case study of farmland ontology was conducted for describing the framework. The strength of this framework is that it provides interpretation strategies and global framework for GEOBIA with the property of objective, overall, universal, universality, etc., which avoids inconsistencies caused by different experts' experience and provides an objective model for mage analysis.

  10. GEOGRAPHICAL ANALYSIS OF FOREST FLORA OF THE CENTRAL CISCAUCASIA

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    I. L. Ivanov

    2014-01-01

    Full Text Available Abstract. Aim. Forest flora of the Central Ciscaucasia in General is a relict, geographically situated in the steppe zone. Composing flora elements have different types of habitats, concentrated in the natural physical-geographical unit where isolated from the main habitats. Comparative analysis of the geographic, ecological and systematic components of forest flora will provide data about the correlation of these parameters identify the leading group. Location. The Central CiscaucasiaMethods. We made the geographical and systematic ranges of forest flora of the Central Ciscaucasia and their comparative analysis is conducted.Results. Geographical analysis of forest flora of the Central Ciscaucasia revealed 16 geographical elements, grouped in 6 categories, among which is the predominant group of boreal geographical elements. It is established that the leading geographical elements are Euro-Caucasian, Caucasian and Sub-Caucasian, numbering 189 species, and are half of the flora. Comparison with ecological spectrum showed that the sequence geographical elements completely different, here leading positions are occupied Northern species as ecologically more conservative, and the Caucasian demonstrate ecological plasticity. In a systematic relation matched warheads geographical and systematic spectra. The scope of the results. The results may be used in comparative Floristics, in its theoretical part in adjusting themodels of the Genesis of the flora.Conclusions. Thus, half of the geographical elements of the forest flora of the Central Ciscaucasia are linked in their distribution of Caucasian floristic province (Euro-Caucasian, Caucasian and Sub-Caucasian. These same geographical elements to predominate in the head part of the spectrum families. Most geographical elements have low ecological plasticity species, their components, do not go beyond the forest plant association, but geographical elements head part of the geographical range

  11. Landscape Analysis of Geographical Names in Hubei Province, China

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    Xixi Chen

    2014-12-01

    Full Text Available Hubei Province is the hub of communications in central China, which directly determines its strategic position in the country’s development. Additionally, Hubei Province is well-known for its diverse landforms, including mountains, hills, mounds and plains. This area is called “The Province of Thousand Lakes” due to the abundance of water resources. Geographical names are exclusive names given to physical or anthropogenic geographic entities at specific spatial locations and are important signs by which humans understand natural and human activities. In this study, geographic information systems (GIS technology is adopted to establish a geodatabase of geographical names with particular characteristics in Hubei Province and extract certain geomorphologic and environmental factors. We carry out landscape analysis of mountain-related geographical names and water-related geographical names respectively. In the end, we calculate the information entropy of geographical names of each county to describe the diversity and inhomogeneity of place names in Hubei province. Our study demonstrates that geographical names represent responses to the cultural landscape and physical environment. The geographical names are more interesting in specific landscapes, such as mountains and rivers.

  12. Fundamental procedures of geographic information analysis

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    Berry, J. K.; Tomlin, C. D.

    1981-01-01

    Analytical procedures common to most computer-oriented geographic information systems are composed of fundamental map processing operations. A conceptual framework for such procedures is developed and basic operations common to a broad range of applications are described. Among the major classes of primitive operations identified are those associated with: reclassifying map categories as a function of the initial classification, the shape, the position, or the size of the spatial configuration associated with each category; overlaying maps on a point-by-point, a category-wide, or a map-wide basis; measuring distance; establishing visual or optimal path connectivity; and characterizing cartographic neighborhoods based on the thematic or spatial attributes of the data values within each neighborhood. By organizing such operations in a coherent manner, the basis for a generalized cartographic modeling structure can be developed which accommodates a variety of needs in a common, flexible and intuitive manner. The use of each is limited only by the general thematic and spatial nature of the data to which it is applied.

  13. From Pixels to Geographic Objects in Remote Sensing Image Analysis

    NARCIS (Netherlands)

    Addink, E.A.; Van Coillie, Frieke M.B.; Jong, Steven M. de

    2012-01-01

    Traditional image analysis methods are mostly pixel-based and use the spectral differences of landscape elements at the Earth surface to classify these elements or to extract element properties from the Earth Observation image. Geographic object-based image analysis (GEOBIA) has received considerabl

  14. Geographic Object-Based Image Analysis: Towards a new paradigm

    NARCIS (Netherlands)

    Blaschke, T.; Hay, G.J.; Kelly, M.; Lang, S.; Hofmann, P.; Addink, E.A.; Queiroz Feitosa, R.; van der Meer, F.D.; van der Werff, H.M.A.; van Coillie, F.; Tiede, A.

    2014-01-01

    The amount of scientific literature on (Geographic) Object-based Image Analysis – GEOBIA has been and still is sharply increasing. These approaches to analysing imagery have antecedents in earlier research on image segmentation and use GIS-like spatial analysis within classification and feature extr

  15. Crime Mapping and Geographical Information Systems in Crime Analysis

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    Murat Dağlar

    2016-04-01

    Full Text Available As essential apparatus in crime analysis, crime mapping and Geographical Information Systems (GIS are being progressively more accepted by police agencies. Development in technology and the accessibility of geographic data sources make it feasible for police departments to use GIS and crime mapping. GIS and crime mapping can be utilized as devices to discover reasons contributing to crime, and hence let law enforcement agencies proactively take action against the crime problems before they become challenging. The purpose of this study is to conduct a literature review of Geographical Information System and Crime Mapping in Crime Analysis and to propose policy recommendations regarding to implementation of crime mapping and GIS. To achieve this purpose, first a historical evaluation of GIS and crime mapping will be rendered and then the importance of place will be explained in terms of assessing crime problems accurately.

  16. Geographical Scale Effects on the Analysis of Leptospirosis Determinants

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    Renata Gracie

    2014-10-01

    Full Text Available Leptospirosis displays a great diversity of routes of exposure, reservoirs, etiologic agents, and clinical symptoms. It occurs almost worldwide but its pattern of transmission varies depending where it happens. Climate change may increase the number of cases, especially in developing countries, like Brazil. Spatial analysis studies of leptospirosis have highlighted the importance of socioeconomic and environmental context. Hence, the choice of the geographical scale and unit of analysis used in the studies is pivotal, because it restricts the indicators available for the analysis and may bias the results. In this study, we evaluated which environmental and socioeconomic factors, typically used to characterize the risks of leptospirosis transmission, are more relevant at different geographical scales (i.e., regional, municipal, and local. Geographic Information Systems were used for data analysis. Correlations between leptospirosis incidence and several socioeconomic and environmental indicators were calculated at different geographical scales. At the regional scale, the strongest correlations were observed between leptospirosis incidence and the amount of people living in slums, or the percent of the area densely urbanized. At the municipal scale, there were no significant correlations. At the local level, the percent of the area prone to flooding best correlated with leptospirosis incidence.

  17. Geographical Scale Effects on the Analysis of Leptospirosis Determinants

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    Gracie, Renata; Barcellos, Christovam; Magalhães, Mônica; Souza-Santos, Reinaldo; Barrocas, Paulo Rubens Guimarães

    2014-01-01

    Leptospirosis displays a great diversity of routes of exposure, reservoirs, etiologic agents, and clinical symptoms. It occurs almost worldwide but its pattern of transmission varies depending where it happens. Climate change may increase the number of cases, especially in developing countries, like Brazil. Spatial analysis studies of leptospirosis have highlighted the importance of socioeconomic and environmental context. Hence, the choice of the geographical scale and unit of analysis used in the studies is pivotal, because it restricts the indicators available for the analysis and may bias the results. In this study, we evaluated which environmental and socioeconomic factors, typically used to characterize the risks of leptospirosis transmission, are more relevant at different geographical scales (i.e., regional, municipal, and local). Geographic Information Systems were used for data analysis. Correlations between leptospirosis incidence and several socioeconomic and environmental indicators were calculated at different geographical scales. At the regional scale, the strongest correlations were observed between leptospirosis incidence and the amount of people living in slums, or the percent of the area densely urbanized. At the municipal scale, there were no significant correlations. At the local level, the percent of the area prone to flooding best correlated with leptospirosis incidence. PMID:25310536

  18. Performance analysis of black hole attacks in geographical routing MANET

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    H.J Shanthi

    2014-10-01

    Full Text Available The MANET (Mobile Adhoc Network is vulnerable to several types of attacks. The most commonly classified attack is black hole attack, which is carried by single or multiple attackers, advertising itself of having a short fresh route to transmit data. The aim is to ensure security against the black hole attack and analyze the performance in geographical routing. The simple method is to send data as small blocks instead of entire data. The traffic is monitored independently in its neighborhood. The mechanism uses geographic information to detect variance in neighbor relations and node movements. We analyze the black hole attack in two popular location based protocol LAR and DREAM. It provides the stimulation study of black hole attack with the minimum attacker and also provides analysis on the parameters such as throughput, packet delivery and delay done with OMNET++ simulator. The simulation results show that packet loss increases and throughput decreases in the network with a black hole node in geographical routing. The proposed mechanism can be combined with existent routing protocols to defend against black hole attacks.

  19. A Longitudinal Intergenerational Analysis of Executive Functions During Early Childhood

    OpenAIRE

    Cuevas, Kimberly; Deater-Deckard, Kirby; Kim-Spoon, Jungmeen; Wang, Zhe; Morasch, Katherine C.; Bell, Martha Ann

    2013-01-01

    Despite the importance of executive function (EF) in both clinical and educational contexts, the etiology of individual differences in early childhood EF remains poorly understood. This study provides the first longitudinal intergenerational analysis of mother-child EF associations during early childhood. A group of children and their mothers (n = 62) completed age-appropriate EF tasks. Mother and child EF were modestly correlated by 24 months of age and this association was stable through 48...

  20. Geographic Object-Based Image Analysis - Towards a new paradigm.

    Science.gov (United States)

    Blaschke, Thomas; Hay, Geoffrey J; Kelly, Maggi; Lang, Stefan; Hofmann, Peter; Addink, Elisabeth; Queiroz Feitosa, Raul; van der Meer, Freek; van der Werff, Harald; van Coillie, Frieke; Tiede, Dirk

    2014-01-01

    The amount of scientific literature on (Geographic) Object-based Image Analysis - GEOBIA has been and still is sharply increasing. These approaches to analysing imagery have antecedents in earlier research on image segmentation and use GIS-like spatial analysis within classification and feature extraction approaches. This article investigates these development and its implications and asks whether or not this is a new paradigm in remote sensing and Geographic Information Science (GIScience). We first discuss several limitations of prevailing per-pixel methods when applied to high resolution images. Then we explore the paradigm concept developed by Kuhn (1962) and discuss whether GEOBIA can be regarded as a paradigm according to this definition. We crystallize core concepts of GEOBIA, including the role of objects, of ontologies and the multiplicity of scales and we discuss how these conceptual developments support important methods in remote sensing such as change detection and accuracy assessment. The ramifications of the different theoretical foundations between the 'per-pixel paradigm' and GEOBIA are analysed, as are some of the challenges along this path from pixels, to objects, to geo-intelligence. Based on several paradigm indications as defined by Kuhn and based on an analysis of peer-reviewed scientific literature we conclude that GEOBIA is a new and evolving paradigm.

  1. [Childhood cancer: a comparative analysis of incidence, mortality, and survival in Goiania (Brazil) and other countries].

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    Braga, Patrícia Emília; Latorre Md, Maria do Rosário Dias de Oliveira; Curado, Maria Paula

    2002-01-01

    Analysis of cancer incidence, mortality, and survival rates can yield geographic and temporal trends that are useful for planning and evaluating health interventions. This article reviews cancer incidence and mortality rates and respective trends around the world in children under 15 years old, as well as their 5-year survival rates in developed and developing countries. We conclude that even though increasing or stable childhood cancer incidence rates and decreasing mortality rates have been observed in developed countries, the trends remain unknown in developing countries. Data from the city of Goiania, Brazil, show stable childhood cancer incidence and mortality rates. Five-year survival rates (48%) in Goiania are similar to those seen in underdeveloped regions and lower than those reported in developed countries (64-70%).

  2. Geographic risk modeling of childhood cancer relative to county-level crops, hazardous air pollutants and population density characteristics in Texas

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    Zhu Li

    2008-09-01

    Full Text Available Abstract Background Childhood cancer has been linked to a variety of environmental factors, including agricultural activities, industrial pollutants and population mixing, but etiologic studies have often been inconclusive or inconsistent when considering specific cancer types. More specific exposure assessments are needed. It would be helpful to optimize future studies to incorporate knowledge of high-risk locations or geographic risk patterns. The objective of this study was to evaluate potential geographic risk patterns in Texas accounting for the possibility that multiple cancers may have similar geographic risks patterns. Methods A spatio-temporal risk modeling approach was used, whereby 19 childhood cancer types were modeled as potentially correlated within county-years. The standard morbidity ratios were modeled as functions of intensive crop production, intensive release of hazardous air pollutants, population density, and rapid population growth. Results There was supportive evidence for elevated risks for germ cell tumors and "other" gliomas in areas of intense cropping and for hepatic tumors in areas of intense release of hazardous air pollutants. The risk for Hodgkin lymphoma appeared to be reduced in areas of rapidly growing population. Elevated spatial risks included four cancer histotypes, "other" leukemias, Central Nervous System (CNS embryonal tumors, CNS other gliomas and hepatic tumors with greater than 95% likelihood of elevated risks in at least one county. Conclusion The Bayesian implementation of the Multivariate Conditional Autoregressive model provided a flexible approach to the spatial modeling of multiple childhood cancer histotypes. The current study identified geographic factors supporting more focused studies of germ cell tumors and "other" gliomas in areas of intense cropping, hepatic cancer near Hazardous Air Pollutant (HAP release facilities and specific locations with increased risks for CNS embryonal tumors and

  3. Sensorimotor Analysis of Early Onset Childhood Psychosis.

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    Ertel, David; Voyat, Gilbert

    1982-01-01

    Jean Piaget's theories about children's cognitive development are applied to the evaluation of childhood psychosis. Problems with the testing of such children are described, and results of a research project that used the Piaget-inspired Uzgiris and Hunt Ordinal Scales of Psychological Development to assess autistic children's cognitive processes…

  4. Frequency of Six Early Childhood Education Approaches: A 10-Year Content Analysis of Early Childhood Education Journal

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    Walsh, Bridget A.; Petty, Karen

    2007-01-01

    The frequency of early childhood education approaches spanning 10 years of publications was investigated. A content analysis of publications (N = 492) from "Early Childhood Education Journal" was conducted. From a previous content analysis six approaches or search words were identified: Bank Street, Head Start, High/Scope, Montessori, Reggio…

  5. Fuzzy surfaces in GIS and geographical analysis theory, analytical methods, algorithms and applications

    CERN Document Server

    Lodwick, Weldon

    2007-01-01

    Surfaces are a central to geographical analysis. Their generation and manipulation are a key component of geographical information systems (GISs). However, geographical surface data is often not precise. When surfaces are used to model geographical entities, the data inherently contains uncertainty in terms of both position and attribute. Fuzzy Surface in GIS and Geographical Analysis sets out a process to identify the uncertainty in geographic entities. It describes how to successfully obtain, model, analyze, and display data, as well as interpret results within the context of GIS. Focusing on uncertainty that arises from transitional boundaries, the book limits its study to three types of uncertainties: intervals, fuzzy sets, and possibility distributions. The book explains that uncertainty in geographical data typically stems from these three and it is only natural to incorporate them into the analysis and display of surface data. The book defines the mathematics associated with each method for analysis,...

  6. Applications of Geographic Information System (GIS) analysis of Lake Uluabat.

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    Hacısalihoğlu, Saadet; Karaer, Feza; Katip, Aslıhan

    2016-06-01

    Lake Uluabat is one of the most important wetlands in Turkey because of its rich biodiversity, lying on a migratory bird route with almost all its shores being covered by submerged plants. The lake has been protected by the Ramsar Convention since 1998. However, the Lake is threatened by natural and anthropogenic stressors as a consequence of its location. Geographic Information System (GIS) analysis is a tool that has been widely used, especially for water quality management in recent years. This study aimed to investigate the water quality and determined most polluted points using GIS analysis of the lake. Temperature, pH, dissolved oxygen, chemical oxygen demand, Kjeldahl nitrogen, total phosphorus, chlorophyll-a, arsenic, boron, iron, and manganese were monitored monthly from June 2008 to May 2009, with the samples taken from 8 points in the lake. Effect of pH, relation of temperature, and Chl-a with other water quality parameters and metals are designated as statistically significant. Data were mapped using ArcGIS 9.1 software and were assessed according to the Turkish Water Pollution Control Regulations (TWPCR). The research also focused on classifying and mapping the water quality in the lake by using the spatial analysis functions of GIS. As a result, it was determined that Lake Uluabat belonged to the 4th class, i.e., highly polluted water, including any water of lower quality. A remarkable portion of the pollution in the water basin was attributed to domestic wastewater discharges, industrial and agricultural activities, and mining.

  7. Catchment delineation and morphometric analysis using geographical information system.

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    Kumar, Manoj; Kumar, Rohitashw; Singh, P K; Singh, Manjeet; Yadav, K K; Mittal, H K

    2015-01-01

    The geographical information system (GIS) has emerged as an efficient tool in delineation of drainage patterns of watershed planning and management. The morphometric parameters of basins can address linear, areal and relief aspects. The study deals with the integrated watershed management of Baliya micro-watersheds, located in the Udaipur district of Rajasthan, India. Morphometric analysis in hydrological investigation is an important aspect and it is inevitable in the development and management of drainage basins. The determination of linear, areal and relief parameters indicate fairly good significance. The low value of the bifurcation ratio of 4.19 revealed that the drainage pattern has not been distorted by structural disturbance. The high value of the elongation ratio (0.68) compared to the circulatory ratio (0.27) indicates an elongated shape of the watershed. The high value of drainage density (5.39 km/km(2)) and stream frequency (12.32) shows that the region has impermeable subsoil material under poor vegetative cover with a low relief factor. The morphometric parameters of relief ratio (0.041) and relative relief (0.99%) show that the watershed can be treated using GIS techniques to determine the morphometric presence of dendritic drainage pattern, with a view to selecting the soil and water conservation measures and water harvesting.

  8. Analysis of Geographic Coordinates of the Meteorological Post at Zrinjevac

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    Drago Špoljarić

    2016-06-01

    Full Text Available The Meteorological Post at Zrinjevac built in 1884 is a public meteorological station where many citizens and visitors can obtain information about temperature, humidity and air pressure in the centre of the town. Based on the available documentation, the paper presents the analysis of geographic coordinates of the post, their reliability (accuracy – referring to whether they determine the real position of the post and who and when determined them. There are also the analysed coordinates given that were established by Ivan Stožir in 1884, then the coordinates read by Guro Pila in 1890 from the new special map of Austro-Hungarian Monarchy and converted in 1941 by Nikolaj Abakumov from rectangular coordinates from the cadastral plan, and finally, the coordinates determined by means of modern GNSS measuring systems. There are also the changes of the form and the contents of the post show window described that took place on the occasion of two great restorations in 1959 and 1993 and were done in accordance with its modernisation. The clock with the 24-hour dial is also described. The times of sunrise and sunset in Zagreb have been checked and recalculated.

  9. GEOGRAPHICAL ANALYSIS OF THE COASTAL FLORA OF THE AZOV SEA

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    Kolomiychuk V. P.

    2012-11-01

    Full Text Available Quantitative indicators of the coastal flora of the Azov Sea are presented. Geographical features of the flora of the region have been analyzed. The major endemic complexes of the flora being investigated are described.

  10. Geographical cost-supply analysis forest biomass for distributed generation in Denmark

    DEFF Research Database (Denmark)

    Möller, Bernd

    2004-01-01

    The article presents a study which uses geographical information system (GIS) to perform cost-supply analysis of wood chips resources for energy production.......The article presents a study which uses geographical information system (GIS) to perform cost-supply analysis of wood chips resources for energy production....

  11. Geographic variations of childhood asthma hospitalization and outpatient visits and proximity to ambient pollution sources at a U.S.-Canada border crossing

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    Rivers Patrick A

    2005-06-01

    Full Text Available Abstract Background Childhood asthma is a significant public health problem in the United States and evidence is accumulating regarding the contribution from traffic and ambient air pollution. This study is a companion piece of a related Buffalo asthma study in adults recently published in the July 2004 issue of American Journal of Public Health. This study focuses on children under 18 years of age diagnosed with asthma during a three-year period (2000–2002. In order to determine the effects of particulate air pollution on public health, we conducted an ecologic study of childhood asthma and point-source respirable particulate air pollution in patients diagnosed with asthma (n = 6,425. Patients diagnosed with gastroenteritis (n = 5,132 were used as controls. Results Although the results of this study show spatial patterns similar to the ones observed in the adult study, a multiple-comparison test shows that EPA-designated focus sites located in Buffalo's east side are statistically (p Conclusion Findings of this study can be useful in geographic targeting and in the design of optimal and preventive measures.

  12. Content Analysis of International Research in Geographical and Environmental Education: 18 Years of Academic Publishing

    Science.gov (United States)

    Kidman, Gillian; Papadimitriou, Fivos

    2012-01-01

    This paper examines the history of the "International Research in Geographical and Environmental Education" (IRGEE) journal in terms of its sustainable future. The development of geographical and environmental education is evaluated, as reflected from the papers published in the journal "IRGEE". A content analysis of all papers and forum sections…

  13. Geographic clustering of firms and urban form: a multivariate analysis

    Science.gov (United States)

    Maoh, Hanna; Kanaroglou, Pavlos

    2007-04-01

    This paper provides an empirical framework that applies spatial statistics methods to assess the relation between the change in the geographical clustering of firms and the emergence of urban form. We contend that where firms locate and eventually cluster give rise to the way commercial and industrial land uses are organized over space, which in turn defines the shape of urban form. Accordingly, the objectives of our work are twofold: (1) to identify the extent and shape of firm clustering and co-location at the intra-metropolitan level, and (2) examine how the change in the geographic clustering of different industries contributes to decentralization and the evolution of urban form. Spatial statistics methods and tools were vital and helped to fulfill these objectives.

  14. Childhood maltreatment and obesity: systematic review and meta-analysis.

    Science.gov (United States)

    Danese, A; Tan, M

    2014-05-01

    Obesity is a prevalent global-health problem associated with substantial morbidity, impairment and economic burden. Because most readily available forms of treatment are ineffective in the long term, it is essential to advance knowledge of obesity prevention by identifying potentially modifiable risk factors. Findings from experimental studies in non-human primates suggest that adverse childhood experiences may influence obesity risk. However, observations from human studies showed heterogeneous results. To address these inconsistencies, we performed Medline, PsycInfo and Embase searches till 1 August 2012 for articles examining the association between childhood maltreatment and obesity. We then conducted a meta-analysis of the identified studies and explored the effects of various possible sources of bias. A meta-analysis of 41 studies (190 285 participants) revealed that childhood maltreatment was associated with elevated risk of developing obesity over the life-course (odds ratio=1.36; 95% confidence interval=1.26-1.47). Results were not explained by publication bias or undue influence of individual studies. Overall, results were not significantly affected by the measures or definitions used for maltreatment or obesity, nor by confounding by childhood or adult socioeconomic status, current smoking, alcohol intake or physical activity. However, the association was not statistically significant in studies of children and adolescents, focusing on emotional neglect, or adjusting for current depression. Furthermore, the association was stronger in samples including more women and whites, but was not influenced by study quality. Child maltreatment is a potentially modifiable risk factor for obesity. Future research should clarify the mechanisms through which child maltreatment affects obesity risk and explore methods to remediate this effect.

  15. Impacts of Scale on Geographic Analysis of Health Data: An Example of Obesity Prevalence

    Directory of Open Access Journals (Sweden)

    Jay Lee

    2014-10-01

    Full Text Available The prevalence of obesity has increased dramatically in recent decades. It is an important public health issue as it causes many other chronic health conditions, such as hypertension, cardiovascular diseases, and type II diabetics. Obesity affects life expectancy and even the quality of lives. Eventually, it increases social costs in many ways due to increasing costs of health care and workplace absenteeism. Using the spatial patterns of obesity prevalence as an example; we show how different geographic units can reveal different degrees of detail in results of analysis. We used both census tracts and census block groups as units of geographic analysis. In addition; to reveal how different geographic scales may impact on the analytic results; we applied geographically weighted regression to model the relationships between obesity rates (dependent variable and three independent variables; including education attainment; unemployment rates; and median family income. Though not including an exhaustive list of explanatory variables; this regression model provides an example for revealing the impacts of geographic scales on analysis of health data. With obesity data based on reported heights and weights on driver’s licenses in Summit County, Ohio, we demonstrated that geographically weighted regression reveals varying spatial trends between dependent and independent variables that conventional regression models such as ordinary least squares regression cannot. Most importantly, analyses carried out with different geographic scales do show very different results. With these findings, we suggest that, while possible, smaller geographic units be used to allow better understanding of the studies phenomena.

  16. Pygrass: An Object Oriented Python Application Programming Interface (API for Geographic Resources Analysis Support System (GRASS Geographic Information System (GIS

    Directory of Open Access Journals (Sweden)

    Marco Ciolli

    2013-03-01

    Full Text Available PyGRASS is an object-oriented Python Application Programming Interface (API for Geographic Resources Analysis Support System (GRASS Geographic Information System (GIS, a powerful open source GIS widely used in academia, commercial settings and governmental agencies. We present the architecture of the PyGRASS library, covering interfaces to GRASS modules, vector and raster data, with a focus on the new capabilities that it provides to GRASS users and developers. Our design concept of the module interface allows the direct linking of inputs and outputs of GRASS modules to create process chains, including compatibility checks, process control and error handling. The module interface was designed to be easily extended to work with remote processing services (Web Processing Service (WPS, Web Service Definition Language (WSDL/Simple Object Access Protocol (SOAP. The new object-oriented Python programming API introduces an abstract layer that opens the possibility to use and access transparently the efficient raster and vector functions of GRASS that are implemented in C. The design goal was to provide an easy to use, but powerful, Python interface for users and developers who are not familiar with the programming language C and with the GRASS C-API. We demonstrate the capabilities, scalability and performance of PyGRASS with several dedicated tests and benchmarks. We compare and discuss the results of the benchmarks with dedicated C implementations.

  17. DEACTIVATION AND DECOMMISSIONING PLANNING AND ANALYSIS WITH GEOGRAPHIC INFORMATION SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    Bollinger, J; William Austin, W; Larry Koffman, L

    2007-09-17

    From the mid-1950's through the 1980's, the U.S. Department of Energy's Savannah River Site produced nuclear materials for the weapons stockpile, for medical and industrial applications, and for space exploration. Although SRS has a continuing defense-related mission, the overall site mission is now oriented toward environmental restoration and management of legacy chemical and nuclear waste. With the change in mission, SRS no longer has a need for much of the infrastructure developed to support the weapons program. This excess infrastructure, which includes over 1000 facilities, will be decommissioned and demolished over the forthcoming years. Dispositioning facilities for decommissioning and deactivation requires significant resources to determine hazards, structure type, and a rough-order-of-magnitude estimate for the decommissioning and demolition cost. Geographic information systems (GIS) technology was used to help manage the process of dispositioning infrastructure and for reporting the future status of impacted facilities.

  18. Geographical classification of Epimedium based on HPLC fingerprint analysis combined with multi-ingredients quantitative analysis.

    Science.gov (United States)

    Xu, Ning; Zhou, Guofu; Li, Xiaojuan; Lu, Heng; Meng, Fanyun; Zhai, Huaqiang

    2017-05-01

    A reliable and comprehensive method for identifying the origin and assessing the quality of Epimedium has been developed. The method is based on analysis of HPLC fingerprints, combined with similarity analysis, hierarchical cluster analysis (HCA), principal component analysis (PCA) and multi-ingredient quantitative analysis. Nineteen batches of Epimedium, collected from different areas in the western regions of China, were used to establish the fingerprints and 18 peaks were selected for the analysis. Similarity analysis, HCA and PCA all classified the 19 areas into three groups. Simultaneous quantification of the five major bioactive ingredients in the Epimedium samples was also carried out to confirm the consistency of the quality tests. These methods were successfully used to identify the geographical origin of the Epimedium samples and to evaluate their quality.

  19. Spatial analysis of the relationship between early childhood mortality and malaria endemicity in Malawi

    Directory of Open Access Journals (Sweden)

    Lawrence N. Kazembe

    2007-11-01

    Full Text Available Spatial differences in mortality have been reported in Africa amongst children under-five years of age. Risk factors contributing to this geographical variation include bio-demographic and socio-economic factors, the prevalence of infectious diseases and the variability in the quality of child health care. This paper is concerned with investigating the link between early childhood mortality and malaria risk. We used data from the Mapping Malaria Risk in Africa (MARA and Demographic and Health Survey (DHS databases to explore this relationship. The DHS survey included questions on bio-demographic and socio-economic status, complete birth histories and survival time of each child within the five years preceding the survey. Survival times were computed in months until death or until the survey was done. The malaria risk was based on prevalence data estimated at the precise DHS sampling location. A spatial Cox regression model was applied to analyze child survival, assessing the influence of both individual-specific factors, malaria endemicity and group-specific environmental factors, approximated by geographical location. Geographical location was considered at subdistrict level. Our analysis shows that although malaria endemicity is not associated with the risk of infant mortality, it is an important risk factor for child mortality. The results confirm the effects of bio-demographic and socio-economic variables (maternal education, maternal age, birth order and place of residence on infant and child mortality. The subdistrict-specific variation of infant and child mortality shows a rural-urban distinction with a relatively lower risk of mortality in main urban areas.

  20. Dimensionality of an Early Childhood Scale Using Rasch Analysis and Confirmatory Factor Analysis.

    Science.gov (United States)

    Banerji, Madhabi; Smith, Richard M.; Dedrick, Robert F.

    1997-01-01

    This paper explores the use of Rasch analysis and linear confirmatory factor analysis to investigate the dimensionality of an early childhood test, the Gesell School Readiness Screening Test (F. Ilg and others, 1978). Discusses empirical analyses of results from 523 kindergarten students using both methods. (SLD)

  1. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

    DEFF Research Database (Denmark)

    Felix, Janine F; Bradfield, Jonathan P; Monnereau, Claire;

    2016-01-01

    A large number of genetic loci are associated with adult body mass index. However, the genetics of childhood body mass index are largely unknown. We performed a meta-analysis of genome-wide association studies of childhood body mass index, using sex- and age-adjusted standard deviation scores. We...

  2. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

    NARCIS (Netherlands)

    J.F. Felix (Janine); J.P. Bradfield (Jonathan); C. Monnereau; R.J.P. van der Valk (Ralf); E. Stergiakouli (Evie); A. Chesi (Alessandra); R. Gaillard (Romy); B. Feenstra (Bjarke); E. Thiering (Elisabeth); E. Kreiner-Møller (Eskil); A. Mahajan (Anubha); Niina Pitkänen; R. Joro (Raimo); A. Cavadino (Alana); V. Huikari (Ville); S. Franks (Steve); M. Groen-Blokhuis (Maria); D.L. Cousminer (Diana); J.A. Marsh (Julie); T. Lehtimäki (Terho); J.A. Curtin (John); J. Vioque (Jesus); T.S. Ahluwalia (Tarunveer Singh); R. Myhre (Ronny); T.S. Price (Thomas); Natalia Vilor-Tejedor; L. Yengo (Loic); N. Grarup (Niels); I. Ntalla (Ioanna); W.Q. Ang (Wei); M. Atalay (Mustafa); H. Bisgaard (Hans); A.I.F. Blakemore (Alexandra); A. Bonnefond (Amélie); L. Carstensen (Lisbeth); J.G. Eriksson (Johan G.); C. Flexeder (Claudia); L. Franke (Lude); F. Geller (Frank); M. Geserick (Mandy); A.L. Hartikainen; C.M.A. Haworth (Claire M.); J.N. Hirschhorn (Joel N.); A. Hofman (Albert); J.-C. Holm (Jens-Christian); M. Horikoshi (Momoko); J.J. Hottenga (Jouke Jan); J. Huang (Jian); H.N. Kadarmideen (Haja N.); M. Kähönen (Mika); W. Kiess (Wieland); T.A. Lakka (Timo); T.A. Lakka (Timo); A. Lewin (Alex); L. Liang (Liming); L.-P. Lyytikäinen (Leo-Pekka); B. Ma (Baoshan); P. Magnus (Per); S.E. McCormack (Shana E.); G. Mcmahon (George); F.D. Mentch (Frank); C.M. Middeldorp (Christel); C.S. Murray (Clare S.); K. Pahkala (Katja); T.H. Pers (Tune); R. Pfäffle (Roland); D.S. Postma (Dirkje); C. Power (Christine); A. Simpson (Angela); V. Sengpiel (Verena); C. Tiesler (Carla); M. Torrent (Maties); A.G. Uitterlinden (André); J.B.J. van Meurs (Joyce); R. Vinding (Rebecca); J. Waage (Johannes); J. Wardle (Jane); E. Zeggini (Eleftheria); B.S. Zemel (Babette S.); G.V. Dedoussis (George); O. Pedersen (Oluf); P. Froguel (Philippe); J. Sunyer (Jordi); R. Plomin (Robert); B. Jacobsson (Bo); T. Hansen (Torben); J.R. Gonzalez (Juan R.); A. Custovic; O.T. Raitakari (Olli T.); C.E. Pennell (Craig); Elisabeth Widén; D.I. Boomsma (Dorret); G.H. Koppelman (Gerard); S. Sebert (Sylvain); M.-R. Jarvelin (Marjo-Riitta); E. Hypponen (Elina); M.I. McCarthy (Mark); V. Lindi (Virpi); N. Harri (Niinikoski); A. Körner (Antje); K. Bønnelykke (Klaus); J. Heinrich (Joachim); M. Melbye (Mads); F. Rivadeneira Ramirez (Fernando); H. Hakonarson (Hakon); S.M. Ring (Susan); G.D. Smith; T.I.A. Sørensen (Thorkild I.A.); N. Timpson (Nicholas); S.F. Grant; V.W.V. Jaddoe (Vincent W. V.); H.J. Kalkwarf (Heidi J.); J.M. Lappe (Joan M.); V. Gilsanz (Vicente); S.E. Oberfield (Sharon E.); J.A. Shepherd (John A.); A. Kelly (Andrea)

    2016-01-01

    textabstractA large number of genetic loci are associated with adult body mass index. However, the genetics of childhood body mass index are largely unknown.We performed a meta-analysis of genome-wide association studies of childhood body mass index, using sex- and age-adjusted standard deviation sc

  3. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

    NARCIS (Netherlands)

    Felix, Janine F; Bradfield, Jonathan P; Monnereau, Claire; van der Valk, Ralf J P; Stergiakouli, Evie; Chesi, Alessandra; Gaillard, Romy; Feenstra, Bjarke; Thiering, Elisabeth; Kreiner-Møller, Eskil; Mahajan, Anubha; Pitkänen, Niina; Joro, Raimo; Cavadino, Alana; Huikari, Ville; Franks, Steve; Groen-Blokhuis, Maria M; Cousminer, Diana L; Marsh, Julie A; Lehtimäki, Terho; Curtin, John A; Vioque, Jesus; Ahluwalia, Tarunveer S; Myhre, Ronny; Price, Thomas S; Vilor-Tejedor, Natalia; Yengo, Loïc; Grarup, Niels; Ntalla, Ioanna; Ang, Wei; Atalay, Mustafa; Bisgaard, Hans; Blakemore, Alexandra I; Bonnefond, Amelie; Carstensen, Lisbeth; Eriksson, Johan; Flexeder, Claudia; Franke, Lude; Geller, Frank; Geserick, Mandy; Hartikainen, Anna-Liisa; Haworth, Claire M A; Hirschhorn, Joel N; Hofman, Albert; Holm, Jens-Christian; Horikoshi, Momoko; Hottenga, Jouke Jan; Huang, Jinyan; Kadarmideen, Haja N; Kähönen, Mika; Kiess, Wieland; Lakka, Hanna-Maaria; Lakka, Timo A; Lewin, Alexandra M; Liang, Liming; Lyytikäinen, Leo-Pekka; Ma, Baoshan; Magnus, Per; McCormack, Shana E; McMahon, George; Mentch, Frank D; Middeldorp, Christel M; Murray, Clare S; Pahkala, Katja; Pers, Tune H; Pfäffle, Roland; Postma, Dirkje S; Power, Christine; Simpson, Angela; Sengpiel, Verena; Tiesler, Carla M T; Torrent, Maties; Uitterlinden, André G; van Meurs, Joyce B; Vinding, Rebecca; Waage, Johannes; Wardle, Jane; Zeggini, Eleftheria; Zemel, Babette S; Dedoussis, George V; Pedersen, Oluf; Froguel, Philippe; Sunyer, Jordi; Plomin, Robert; Jacobsson, Bo; Hansen, Torben; Gonzalez, Juan R; Custovic, Adnan; Raitakari, Olli T; Pennell, Craig E; Widén, Elisabeth; Boomsma, Dorret I; Koppelman, Gerard H; Sebert, Sylvain; Järvelin, Marjo-Riitta; Hyppönen, Elina; McCarthy, Mark I; Lindi, Virpi; Harri, Niinikoski; Körner, Antje; Bønnelykke, Klaus; Heinrich, Joachim; Melbye, Mads; Rivadeneira, Fernando; Hakonarson, Hakon; Ring, Susan M; Smith, George Davey; Sørensen, Thorkild I A; Timpson, Nicholas J; Grant, Struan F A; Jaddoe, Vincent W V

    2015-01-01

    A large number of genetic loci are associated with adult body mass index. However, the genetics of childhood body mass index are largely unknown. We performed a meta-analysis of genome-wide association studies of childhood body mass index, using sex- and age-adjusted standard deviation scores. We in

  4. Birth order and childhood type 1 diabetes risk: a pooled analysis of 31 observational studies

    DEFF Research Database (Denmark)

    Cardwell, Chris R; Stene, Lars C; Joner, Geir;

    2011-01-01

    The incidence rates of childhood onset type 1 diabetes are almost universally increasing across the globe but the aetiology of the disease remains largely unknown. We investigated whether birth order is associated with the risk of childhood diabetes by performing a pooled analysis of previous...

  5. STANDARD ANALYSIS OF TEACHERS AND EARLY CHILDHOOD EDUCATION

    Directory of Open Access Journals (Sweden)

    Sayid Habiburrahman

    2016-01-01

    Full Text Available Public awareness of the importance of early childhood education is getting better with the emergence of various forms of diverse early childhood institutions. This phenomenon is very interesting to continue to develop early childhood education program. This consciousness departs from understanding the purpose of early childhood education programs that facilitate the optimal growth and development of children in accordance with the norms and values. Through proper educational programs, the child will be Able to develop all potentials, from the physical aspect, social, moral, emotional, personality and the other aspects.

  6. Geographical analysis of the Uredinales flora of Poland

    Directory of Open Access Journals (Sweden)

    Tomasz Majewski

    2014-11-01

    Full Text Available The analysis of the Polish flora of the order Uredinales is based on a simultaneously published descriptive elaboration (M a j e w s k i 1977, ms. The information on the Uredinales flora of Poland has been compared as far as possible with the data obtained from the analysis of the flora of sever al other countries in Europe with a different type of vegetations. In a chapter devoted to the statistics of the flora of Polish rust fungi the number of genera and species of these fungi in Poland is discussed, as well as their life cycles and host plants. The distribution of Uredinales in Poland is analysed on the basis of the A r w i d s s o n - D u r r i e u classification modified by the author, and particular attention is paid to the depedence of the range of the fungus on its life cycle and the occurrence of the host. Changes in the flora a result of its synantropization are also considered. The Polish Uredinales are divided into several groups on the basis of range, and example of their distribution involving historical factors are discussed.

  7. Statistical and Scientometric Analysis of International Research in Geographical and Environmental Education

    Science.gov (United States)

    Papadimitriou, Fivos; Kidman, Gillian

    2012-01-01

    Certain statistic and scientometric features of articles published in the journal "International Research in Geographical and Environmental Education" (IRGEE) are examined in this paper for the period 1992-2009 by applying nonparametric statistics and Shannon's entropy (diversity) formula. The main findings of this analysis are: (a) after 2004,…

  8. Key Technology Research on Open Architecture for The Sharing of Heterogeneous Geographic Analysis Models

    Science.gov (United States)

    Yue, S. S.; Wen, Y. N.; Lv, G. N.; Hu, D.

    2013-10-01

    In recent years, the increasing development of cloud computing technologies laid critical foundation for efficiently solving complicated geographic issues. However, it is still difficult to realize the cooperative operation of massive heterogeneous geographical models. Traditional cloud architecture is apt to provide centralized solution to end users, while all the required resources are often offered by large enterprises or special agencies. Thus, it's a closed framework from the perspective of resource utilization. Solving comprehensive geographic issues requires integrating multifarious heterogeneous geographical models and data. In this case, an open computing platform is in need, with which the model owners can package and deploy their models into cloud conveniently, while model users can search, access and utilize those models with cloud facility. Based on this concept, the open cloud service strategies for the sharing of heterogeneous geographic analysis models is studied in this article. The key technology: unified cloud interface strategy, sharing platform based on cloud service, and computing platform based on cloud service are discussed in detail, and related experiments are conducted for further verification.

  9. Cluster Analysis of Childhood Temperament Data on Adoptees.

    Science.gov (United States)

    Maurer, Ralph; And Others

    1980-01-01

    Results concur with the Thomas-Chess findings in identifying three main temperament groups: difficult, easy, and slow to warm up. Membership in the difficult group predicted later childhood behavior disorder in both sexes. (Author)

  10. Childhood obesity in transition zones: an analysis using structuration theory.

    Science.gov (United States)

    Chan, Christine; Deave, Toity; Greenhalgh, Trisha

    2010-07-01

    Childhood obesity is particularly prevalent in areas that have seen rapid economic growth, urbanisation, cultural transition, and commodification of food systems. Structuration theory may illuminate the interaction between population and individual-level causes of obesity. We conducted in-depth ethnographies of six overweight/obese and four non-overweight preschool children in Hong Kong, each followed for 12-18 months. Analysis was informed by Stones' strong structuration theory. Risk factors played out differently for different children as social structures were enacted at the level of family and preschool. The network of caregiving roles and relationships around the overweight/obese child was typically weak and disjointed, and the primary caregiver appeared confused by mixed messages about what is normal, expected and legitimate behaviour. In particular, external social structures created pressure to shift childcare routines from the logic of nurturing to the logic of consumption. Our findings suggest that threats to what Giddens called ontological security in the primary caregiver may underpin the poor parenting, family stress and weak mealtime routines that mediate the relationship between an obesogenic environment and the development of obesity in a particular child. This preliminary study offers a potentially transferable approach for studying emerging epidemics of diseases of modernity in transition societies.

  11. Transportation Routing Analysis Geographic Information System (TRAGIS) User's Manual

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, PE

    2003-09-18

    The Transportation Routing Analysis Geographic Information System (TRAGIS) model is used to calculate highway, rail, or waterway routes within the United States. TRAGIS is a client-server application with the user interface and map data files residing on the user's personal computer and the routing engine and network data files on a network server. The user's manual provides documentation on installation and the use of the many features of the model.

  12. Geographical Analysis of Conflict Minerals Utilizing Laser-Induced Breakdown Spectroscopy

    Science.gov (United States)

    2012-01-01

    geographic heterogeneity. The approach of Melcher et al. [2,8] is principally based on quantitative elemental and isotope analysis to detect these...13] M.A. Wise, Geochemistry and crystal chemistry of Nb, Ta and Sn minerals from the Yellowknife pegmatite field, N.W.T. PhD thesis, Univ. Manitoba...metal pegmatite bodies of Jharkhand, Bihar, and Karnataka; a significant milestone in the growth of ore- geochemistry in India, Mem. Geol. Soc. India 73

  13. Geographic context scanning & analysis: il Modello Di Riferimento e le Operazioni

    Directory of Open Access Journals (Sweden)

    Maurizio Rosina

    2013-12-01

    Full Text Available The aim of the article is to define a Reference Model and the operators which allow to perform the activities of Geographic ContextScanning & Analysis. The theory and methods exposed will contribute to the evolution of the framework GEOPOI 2.0, developed and delivered by Sogei and acc essed as a SaaS (Software as a Serv ice by a number of Public Administrations for your own institutional tasks.

  14. Meta-analysis of psychological treatments for posttraumatic stress disorder in adult survivors of childhood abuse

    OpenAIRE

    Ehring, T.; Welboren, R; Morina, N; Wicherts, J.M.; J. Freitag; Emmelkamp, P.M.G.

    2014-01-01

    Posttraumatic stress disorder (PTSD) is highly prevalent in adult survivors of childhood sexual and/or physical abuse. However, intervention studies focusing on this group of patients are underrepresented in earlier meta-analyses on the efficacy of PTSD treatments. The current meta-analysis exclusively focused on studies evaluating the efficacy of psychological interventions for PTSD in adult survivors of childhood abuse. Sixteen randomized controlled trials meeting inclusion criteria could b...

  15. Geographical analysis of 'conflict minerals' utilizing laser-induced breakdown spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Hark, Richard R., E-mail: hark@juniata.edu [Department of Chemistry, Juniata College, Huntingdon, PA 16652 (United States); Remus, Jeremiah J. [Department of Electrical and Computer Engineering, Clarkson University, Potsdam, NY 13699 (United States); East, Lucille J. [Applied Spectra, Inc., Fremont, CA 94538 (United States); Harmon, Russell S. [Department of Marine, Earth and Atmospheric Sciences, North Carolina State University, Raleigh, NC 27695 (United States); Wise, Michael A. [Department of Mineral Sciences, Smithsonian Institution, Washington, DC 20013 (United States); Tansi, Benjamin M.; Shughrue, Katrina M. [Department of Chemistry, Juniata College, Huntingdon, PA 16652 (United States); Dunsin, Kehinde S. [Department of Electrical and Computer Engineering, Clarkson University, Potsdam, NY 13699 (United States); Liu, Chunyi [Applied Spectra, Inc., Fremont, CA 94538 (United States)

    2012-08-15

    Laser-induced breakdown spectroscopy (LIBS) offers a means of rapidly distinguishing different geographic sources for a mineral because the LIBS plasma emission spectrum provides information on the chemical composition (i.e. geochemical fingerprint) of a geomaterial. An application of this approach with potentially significant commercial and political importance is the spectral fingerprinting of 'conflict minerals' such as columbite-tantalite ('coltan'). Following a successful pilot study of a columbite-tantalite suite from North America, a more geographically diverse set of 57 samples from 37 locations around the world was analyzed using a commercially available LIBS system. The LIBS spectra were analyzed using advanced multivariate statistical signal processing techniques. Partial least squares discriminant analysis (PLSDA) resulted in a correct place-level geographic classification at success rates above 90%. The possible role of rare-earth elements (REEs) as a factor contributing to the high levels of sample discrimination was explored. These results provide additional evidence that LIBS has the potential to be utilized in the field as a real-time screening tool to discriminate between columbite-tantalite ores of different provenance. - Highlights: Black-Right-Pointing-Pointer Analysis of columbite-tantalite using laser-induced breakdown spectroscopy (LIBS) Black-Right-Pointing-Pointer Chemometric analysis (PLSDA) affords 90-100% correct sample classification. Black-Right-Pointing-Pointer Possible role of rare-earth elements in the high level of sample discrimination.

  16. αA crystallin may protect against geographic atrophy-meta-analysis of cataract vs. cataract surgery for geographic atrophy and experimental studies.

    Directory of Open Access Journals (Sweden)

    Peng Zhou

    Full Text Available BACKGROUND: Cataract and geographic atrophy (GA, also called advanced "dry" age-related macular degeneration are the two major causes of visual impairment in the developed world. The association between cataract surgery and the development of GA was controversial in previous studies. METHODS/PRINCIPAL FINDINGS: We performed a meta-analysis by pooling the current evidence in literature and found that cataract is associated with an increased risk of geographic atrophy with a summary odds ratio (OR of 3.75 (95% CI: 95% CI: 1.84-7.62. However, cataract surgery is not associated with the risk of geographic atrophy (polled OR=3.23, 95% CI: 0.63-16.47. Further experiments were performed to analyze how the αA-crystallin, the major component of the lens, influences the development of GA in a mouse model. We found that theαA-crystallin mRNA and protein expression increased after oxidative stress induced by NaIO(3 in immunohistochemistry of retinal section and western blot of posterior eyecups. Both functional and histopathological evidence confirmed that GA is more severe in αA-crystallin knockout mice compared to wild-type mice. CONCLUSIONS: Therefore, αA-crystallin may protect against geographic atrophy. This study provides a better understanding of the relationship between cataract, cataract surgery, and GA.

  17. Social Network Analysis and Qualitative Interviews for Assessing Geographic Characteristics of Tourism Business Networks.

    Science.gov (United States)

    Kelman, Ilan; Luthe, Tobias; Wyss, Romano; Tørnblad, Silje H; Evers, Yvette; Curran, Marina Martin; Williams, Richard J; Berlow, Eric L

    2016-01-01

    This study integrates quantitative social network analysis (SNA) and qualitative interviews for understanding tourism business links in isolated communities through analysing spatial characteristics. Two case studies are used, the Surselva-Gotthard region in the Swiss Alps and Longyearbyen in the Arctic archipelago of Svalbard, to test the spatial characteristics of physical proximity, isolation, and smallness for understanding tourism business links. In the larger Surselva-Gotthard region, we found a strong relationship between geographic separation of the three communities on compartmentalization of the collaboration network. A small set of businesses played a central role in steering collaborative decisions for this community, while a group of structurally 'peripheral' actors were less influential. By contrast, the business community in Svalbard showed compartmentalization that was independent of geographic distance between actors. Within towns of similar size and governance scale, Svalbard is more compartmentalized, and those compartments are not driven by geographic separation of the collaboration clusters. This compartmentalization in Svalbard was reflected in a lower density of formal business collaboration ties compared to the communities of the Alps. We infer that the difference is due to Svalbard having higher cultural diversity and population turnover than the Alps communities. We propose that integrating quantitative network analysis from simple surveys with qualitative interviews targeted from the network results is an efficient general approach to identify regionally specific constraints and opportunities for effective governance.

  18. Social Network Analysis and Qualitative Interviews for Assessing Geographic Characteristics of Tourism Business Networks.

    Directory of Open Access Journals (Sweden)

    Ilan Kelman

    Full Text Available This study integrates quantitative social network analysis (SNA and qualitative interviews for understanding tourism business links in isolated communities through analysing spatial characteristics. Two case studies are used, the Surselva-Gotthard region in the Swiss Alps and Longyearbyen in the Arctic archipelago of Svalbard, to test the spatial characteristics of physical proximity, isolation, and smallness for understanding tourism business links. In the larger Surselva-Gotthard region, we found a strong relationship between geographic separation of the three communities on compartmentalization of the collaboration network. A small set of businesses played a central role in steering collaborative decisions for this community, while a group of structurally 'peripheral' actors were less influential. By contrast, the business community in Svalbard showed compartmentalization that was independent of geographic distance between actors. Within towns of similar size and governance scale, Svalbard is more compartmentalized, and those compartments are not driven by geographic separation of the collaboration clusters. This compartmentalization in Svalbard was reflected in a lower density of formal business collaboration ties compared to the communities of the Alps. We infer that the difference is due to Svalbard having higher cultural diversity and population turnover than the Alps communities. We propose that integrating quantitative network analysis from simple surveys with qualitative interviews targeted from the network results is an efficient general approach to identify regionally specific constraints and opportunities for effective governance.

  19. Geographically selective assortment of cycles in pandemics: meta-analysis of data collected by Chizhevsky.

    Science.gov (United States)

    Gumarova, L; Cornélissen, G; Hillman, D; Halberg, F

    2013-10-01

    In the incidence patterns of cholera, diphtheria and croup during the past when they were of epidemic proportions, we document a set of cycles (periods), one of which was reported and discussed by A. L. Chizhevsky in the same data with emphasis on the mirroring in human disease of the ~11-year sunspot cycle. The data in this study are based on Chizhevsky’s book The Terrestrial Echo of Solar Storms and on records from the World Health Organization. For meta-analysis, we used the extended linear and nonlinear cosinor. We found a geographically selective assortment of various cycles characterizing the epidemiology of infections, which is the documented novel topic of this paper, complementing the earlier finding in the 21st century or shortly before, of a geographically selective assortment of cycles characterizing human sudden cardiac death. Solar effects, if any, interact with geophysical processes in contributing to this assortment.

  20. Geographic market suitability analysis for low- and intermediate-temperature solar IPH systems

    Energy Technology Data Exchange (ETDEWEB)

    Turner, A.K.; Weber, J.C.; DeAngelis, M.

    1981-12-01

    Previous studies of the industrial market for solar energy systems have considered the level of solar radiation as the main determinant of geographic markets in the US. This study evaluates geographical markets extensively based on such criteria as output of different types of low- and intermediate-temperature solar thermal collectors, air quality constraints for competitive fuels, state solar tax incentives, fuel costs, low industrial use of coal, high industrial growth areas, and industry energy consumption in different parts of the US. Market suitability analysis and mapping techniques, refined in the past 20 years by land use planners, were used to evaluate geographical markets. A computer-aided system, Generalized Map Analysis Planning System (GMAPS), performed interactive, cellular, computer mapping, and composite mapping. Results indicate that the US Southwest and West are the most attractive geographical markets for solar IPH, based on an equal weighting of the evaluation criteria. The West North-Central and East South-Central regions appear to have the least attractive markets. Specific areas within states where solar IPH systems have distinct marketing advantages also are apparent from the composite maps. However, when different weights are assigned to the various criteria, the results change significantly for some regions of the country, such as the New England, Mid-Atlantic, and West South-Central 2 regions. The results of this work will become less valid in the future as state incentives for solar IPH, air quality regulations, and the status of competitive fuels all change. Volume I contains study results and maps.

  1. Geographical analysis of ``conflict minerals'' utilizing laser-induced breakdown spectroscopy

    Science.gov (United States)

    Hark, Richard R.; Remus, Jeremiah J.; East, Lucille J.; Harmon, Russell S.; Wise, Michael A.; Tansi, Benjamin M.; Shughrue, Katrina M.; Dunsin, Kehinde S.; Liu, Chunyi

    2012-08-01

    Laser-induced breakdown spectroscopy (LIBS) offers a means of rapidly distinguishing different geographic sources for a mineral because the LIBS plasma emission spectrum provides information on the chemical composition (i.e. geochemical fingerprint) of a geomaterial. An application of this approach with potentially significant commercial and political importance is the spectral fingerprinting of "conflict minerals" such as columbite-tantalite ("coltan"). Following a successful pilot study of a columbite-tantalite suite from North America, a more geographically diverse set of 57 samples from 37 locations around the world was analyzed using a commercially available LIBS system. The LIBS spectra were analyzed using advanced multivariate statistical signal processing techniques. Partial least squares discriminant analysis (PLSDA) resulted in a correct place-level geographic classification at success rates above 90%. The possible role of rare-earth elements (REEs) as a factor contributing to the high levels of sample discrimination was explored. These results provide additional evidence that LIBS has the potential to be utilized in the field as a real-time screening tool to discriminate between columbite-tantalite ores of different provenance.

  2. Caesarean delivery and risk of childhood leukaemia: a pooled analysis from the Childhood Leukemia International Consortium (CLIC)

    Science.gov (United States)

    Marcotte, Erin L; Thomopoulos, Thomas P; Infante-Rivard, Claire; Clavel, Jacqueline; Petridou, Eleni Th; Schüz, Joachim; Ezzat, Sameera; Dockerty, John D; Metayer, Catherine; Magnani, Corrado; Scheurer, Michael E; Mueller, Beth A; Mora, Ana M; Wesseling, Catharina; Skalkidou, Alkistis; Rashed, Wafaa M; Francis, Stephen S; Ajrouche, Roula; Erdmann, Friederike; Orsi, Laurent; Spector, Logan G

    2017-01-01

    Summary Background Results from case-control studies have shown an increased risk of acute lymphoblastic leukaemia (ALL) in young children born by caesarean delivery, and prelabour caesarean delivery in particular; however, an association of method of delivery with childhood leukaemia subtypes has yet to be established. We therefore did a pooled analysis of data to investigate the association between childhood leukaemia and caesarean delivery. Methods We pooled data from 13 case-control studies from the Childhood Leukemia International Consortium done in nine countries (Canada, Costa Rica, Egypt, France, Germany, Greece, Italy, New Zealand, and the USA) for births from 1970-2013. We analysed caesarean delivery overall and by indications that probably resulted in prelabour caesarean delivery or emergency caesarean delivery. We used multivariable logistic regression models, adjusted for child's birthweight, sex, age, ethnic origin, parental education, maternal age, and study, to estimate odds ratios (ORs) and 95% CIs for the risk of ALL and acute myeloid leukaemia (AML) in children aged 0-14 years at diagnosis. Findings The studies provided data for 8780 ALL cases, 1332 AML cases, and 23 459 controls, of which the birth delivery method was known for 8655 (99%) ALL cases, 1292 (97%) AML cases, and 23 351 (>99%) controls. Indications for caesarean delivery were available in four studies (there were caesarean deliveries for 1061 of 4313 ALL cases, 138 of 664 AML cases, and 1401 of 5884 controls). The OR for all indications of caesarean delivery and ALL was 1.06 (95% CI 0.99–1.13), and was significant for prelabour caesarean delivery and ALL (1.23 [1.04-1.47]; p=0.018). Emergency caesarean delivery was not associated with ALL (OR 1.02 [95% CI 0.81-1.30]). AML was not associated with caesarean delivery (all indications OR 0.99 [95% CI 0.84-1.17]; prelabour caesarean delivery 0.83 [0.54-1.26]; and emergency caesarean delivery 1.05 [0.63-1.77]). Interpretation Our

  3. 1998 Baseline Sampling and Analysis Sampling Locations, Geographic NAD83, LOSCO (2004) [BSA_1998_sample_locations_LOSCO_2004

    Data.gov (United States)

    Louisiana Geographic Information Center — The monitor point data set was produced as a part of the Baseline Sampling and Analysis program coordinated by the Louisiana Oil Spill Coordinator's Office. This...

  4. 1999 Baseline Sampling and Analysis Sampling Locations, Geographic NAD83, LOSCO (2004) [BSA_1999_sample_locations_LOSCO_2004

    Data.gov (United States)

    Louisiana Geographic Information Center — The monitor point data set was produced as a part of the Baseline Sampling and Analysis program coordinated by the Louisiana Oil Spill Coordinator's Office. This...

  5. 1997 Baseline Sampling and Analysis Sample Locations, Geographic NAD83, LOSCO (2004) [BSA_1997_sample_locations_LOSCO_2004

    Data.gov (United States)

    Louisiana Geographic Information Center — The monitor point data set was produced as a part of the Baseline Sampling and Analysis (BSA) program coordinated by the Louisiana Oil Spill Coordinator's Office....

  6. Do childhood externalizing disorders predict adult depression? A meta-analysis.

    Science.gov (United States)

    Loth, Annemarie K; Drabick, Deborah A G; Leibenluft, Ellen; Hulvershorn, Leslie A

    2014-10-01

    Childhood externalizing disorders have been linked to adult affective disorders, although some studies fail to substantiate this finding. Multiple longitudinal cohort studies identifying childhood psychopathology and their association with adult psychiatric illness have been published. To examine the association between childhood externalizing symptoms or disorders and the development of adult depression across cohorts, a meta-analysis was performed. Potential studies were identified using a PubMed search through November 2013. All published, prospective, longitudinal, community-sampled cohort studies of children (≤ 13 years) with externalizing symptoms or disorders (aggression, conduct problems, oppositional defiant disorder, conduct disorder), reassessed in adulthood (≥ 18 years) for depressive disorders (major depressive disorder, depressive disorder NOS, or dysthymic disorder) were included. A random effects model was used to summarize the pooled effect sizes. Ancillary analyses considered covariates that could account for variance among studies. Ten studies representing eight cohorts of children initially assessed at age 13 or younger (N = 17,712) were included in the meta-analysis. Childhood externalizing behavior was associated with adult depressive disorders (OR = 1.52, 95% confidence interval = 1.27-1.80, p < 0.0001). Utilizing Orwin's Fail-safe N approach, 263 studies with a mean odds ratio of 1.0 would have to be added to the analysis before the cumulative effect would become trivial. Externalizing psychopathology in childhood is associated with the development of unipolar depressive disorders in adulthood.

  7. Geographic distribution of suicide and railway suicide in Belgium, 2008-2013: a principal component analysis.

    Science.gov (United States)

    Strale, Mathieu; Krysinska, Karolina; Overmeiren, Gaëtan Van; Andriessen, Karl

    2016-04-20

    This study investigated the geographic distribution of suicide and railway suicide in Belgium over 2008--2013 on local (i.e., district or arrondissement) level. There were differences in the regional distribution of suicide and railway suicides in Belgium over the study period. Principal component analysis identified three groups of correlations among population variables and socio-economic indicators, such as population density, unemployment, and age group distribution, on two components that helped explaining the variance of railway suicide at a local (arrondissement) level. This information is of particular importance to prevent suicides in high-risk areas on the Belgian railway network.

  8. [Temporal and geographical analysis of snakebite envenoming in Veracruz, Mexico (2003-2012)].

    Science.gov (United States)

    Yañez-Arenas, Carlos

    2014-12-01

    Through the period 2003-2012, a temporal and geographical analysis was performed to characterize the snakebite envenoming in the state of Veracruz. Bite records were obtained during this decade and the incidence rate per year was estimated in order to evaluate its spatial and temporal distribution. Furthermore, a smoothed rate of snakebites was calculated per municipality. Snakebite rates have remained constant over time, in spite of fluctuations, which suggest that better prevention strategies are necessary to reduce this phenomenon. Municipalities with the highest smoothed rate are located in the northern portion of the state.

  9. Geographic information systems, remote sensing, and spatial analysis activities in Texas, 2002-07

    Science.gov (United States)

    Pearson, D.K.; Gary, R.H.; Wilson, Z.D.

    2007-01-01

    Geographic information system (GIS) technology has become an important tool for scientific investigation, resource management, and environmental planning. A GIS is a computer-aided system capable of collecting, storing, analyzing, and displaying spatially referenced digital data. GIS technology is particularly useful when analyzing a wide variety of spatial data such as with remote sensing and spatial analysis. Remote sensing involves collecting remotely sensed data, such as satellite imagery, aerial photography, or radar images, and analyzing the data to gather information or investigate trends about the environment or the Earth's surface. Spatial analysis combines remotely sensed, thematic, statistical, quantitative, and geographical data through overlay, modeling, and other analytical techniques to investigate specific research questions. It is the combination of data formats and analysis techniques that has made GIS an essential tool in scientific investigations. This document presents information about the technical capabilities and project activities of the U.S. Geological Survey (USGS) Texas Water Science Center (TWSC) GIS Workgroup from 2002 through 2007.

  10. Geographic information systems, remote sensing, and spatial analysis activities in Texas, 2008-09

    Science.gov (United States)

    ,

    2009-01-01

    Geographic information system (GIS) technology has become an important tool for scientific investigation, resource management, and environmental planning. A GIS is a computer-aided system capable of collecting, storing, analyzing, and displaying spatially referenced digital data. GIS technology is useful for analyzing a wide variety of spatial data. Remote sensing involves collecting remotely sensed data, such as satellite imagery, aerial photography, or radar images, and analyzing the data to gather information or investigate trends about the environment or the Earth's surface. Spatial analysis combines remotely sensed, thematic, statistical, quantitative, and geographical data through overlay, modeling, and other analytical techniques to investigate specific research questions. It is the combination of data formats and analysis techniques that has made GIS an essential tool in scientific investigations. This fact sheet presents information about the technical capabilities and project activities of the U.S. Geological Survey (USGS) Texas Water Science Center (TWSC) GIS Workgroup during 2008 and 2009. After a summary of GIS Workgroup capabilities, brief descriptions of activities by project at the local and national levels are presented. Projects are grouped by the fiscal year (October-September 2008 or 2009) the project ends and include overviews, project images, and Internet links to additional project information and related publications or articles.

  11. Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms

    Science.gov (United States)

    Fisher, Helen L; Murphy, Therese M; Arseneault, Louise; Caspi, Avshalom; Moffitt, Terrie E; Viana, Joana; Hannon, Eilis; Pidsley, Ruth; Burrage, Joe; Dempster, Emma L; Wong, Chloe C Y; Pariante, Carmine M; Mill, Jonathan

    2015-01-01

    Childhood psychotic symptoms are associated with increased rates of schizophrenia, other psychiatric disorders, and suicide attempts in adulthood; thus, elucidating early risk indicators is crucial to target prevention efforts. There is considerable discordance for psychotic symptoms between monozygotic twins, indicating that child-specific non-genetic factors must be involved. Epigenetic processes may constitute one of these factors and have not yet been investigated in relation to childhood psychotic symptoms. Therefore, this study explored whether differences in DNA methylation at age 10 were associated with monozygotic twin discordance for psychotic symptoms at age 12. The Environmental Risk (E-Risk) Longitudinal Twin Study cohort of 2,232 children (1,116 twin pairs) was assessed for age-12 psychotic symptoms and 24 monozygotic twin pairs discordant for symptoms were identified for methylomic comparison. Children provided buccal samples at ages 5 and 10. DNA was bisulfite modified and DNA methylation was quantified using the Infinium HumanMethylation450 array. Differentially methylated positions (DMPs) associated with psychotic symptoms were subsequently tested in post-mortem prefrontal cortex tissue from adult schizophrenia patients and age-matched controls. Site-specific DNA methylation differences were observed at age 10 between monozygotic twins discordant for age-12 psychotic symptoms. Similar DMPs were not found at age 5. The top-ranked psychosis-associated DMP (cg23933044), located in the promoter of the C5ORF42 gene, was also hypomethylated in post-mortem prefrontal cortex brain tissue from schizophrenia patients compared to unaffected controls. These data tentatively suggest that epigenetic variation in peripheral tissue is associated with childhood psychotic symptoms and may indicate susceptibility to schizophrenia and other mental health problems. PMID:26479702

  12. A macrophysiological analysis of energetic constraints on geographic range size in mammals.

    Directory of Open Access Journals (Sweden)

    Salvatore J Agosta

    Full Text Available Physiological processes are essential for understanding the distribution and abundance of organisms, and recently, with widespread attention to climate change, physiology has been ushered back to the forefront of ecological thinking. We present a macrophysiological analysis of the energetics of geographic range size using combined data on body size, basal metabolic rate (BMR, phylogeny and range properties for 574 species of mammals. We propose three mechanisms by which interspecific variation in BMR should relate positively to geographic range size: (i Thermal Plasticity Hypothesis, (ii Activity Levels/Dispersal Hypothesis, and (iii Energy Constraint Hypothesis. Although each mechanism predicts a positive correlation between BMR and range size, they can be further distinguished based on the shape of the relationship they predict. We found evidence for the predicted positive relationship in two dimensions of energetics: (i the absolute, mass-dependent dimension (BMR and (ii the relative, mass-independent dimension (MIBMR. The shapes of both relationships were similar and most consistent with that expected from the Energy Constraint Hypothesis, which was proposed previously to explain the classic macroecological relationship between range size and body size in mammals and birds. The fact that this pattern holds in the MIBMR dimension indicates that species with supra-allometric metabolic rates require among the largest ranges, above and beyond the increasing energy demands that accrue as an allometric consequence of large body size. The relationship is most evident at high latitudes north of the Tropics, where large ranges and elevated MIBMR are most common. Our results suggest that species that are most vulnerable to extinction from range size reductions are both large-bodied and have elevated MIBMR, but also, that smaller species with elevated MIBMR are at heightened risk. We also provide insights into the global latitudinal trends in range

  13. A macrophysiological analysis of energetic constraints on geographic range size in mammals.

    Science.gov (United States)

    Agosta, Salvatore J; Bernardo, Joseph; Ceballos, Gerardo; Steele, Michael A

    2013-01-01

    Physiological processes are essential for understanding the distribution and abundance of organisms, and recently, with widespread attention to climate change, physiology has been ushered back to the forefront of ecological thinking. We present a macrophysiological analysis of the energetics of geographic range size using combined data on body size, basal metabolic rate (BMR), phylogeny and range properties for 574 species of mammals. We propose three mechanisms by which interspecific variation in BMR should relate positively to geographic range size: (i) Thermal Plasticity Hypothesis, (ii) Activity Levels/Dispersal Hypothesis, and (iii) Energy Constraint Hypothesis. Although each mechanism predicts a positive correlation between BMR and range size, they can be further distinguished based on the shape of the relationship they predict. We found evidence for the predicted positive relationship in two dimensions of energetics: (i) the absolute, mass-dependent dimension (BMR) and (ii) the relative, mass-independent dimension (MIBMR). The shapes of both relationships were similar and most consistent with that expected from the Energy Constraint Hypothesis, which was proposed previously to explain the classic macroecological relationship between range size and body size in mammals and birds. The fact that this pattern holds in the MIBMR dimension indicates that species with supra-allometric metabolic rates require among the largest ranges, above and beyond the increasing energy demands that accrue as an allometric consequence of large body size. The relationship is most evident at high latitudes north of the Tropics, where large ranges and elevated MIBMR are most common. Our results suggest that species that are most vulnerable to extinction from range size reductions are both large-bodied and have elevated MIBMR, but also, that smaller species with elevated MIBMR are at heightened risk. We also provide insights into the global latitudinal trends in range size and MIBMR

  14. Scanning for signatures of geographically restricted selection based on population genomics analysis

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Natural selection, as the driving force of human evolution, has direct impact on population differentiation. However, it is still unclear to what extent the genetic differentiation has been caused by natural selection. To explore this question, we performed a genome-wide scan with single nucleotide polymorphism (SNP) data from the International HapMap Project. Single locus FST analysis was applied to assess the frequency difference among populations in autosomes. Based on the empirical distribution of FST, we identified 12669 SNPs correlating to population differentiation and 1853 candidate genes subjected to geographic restricted natural selection. Further interpretation of gene ontogeny revealed 121 categories of biological process with the enrichments of candidate genes. Our results suggest that natural selection may play an important role in human population differentiation. In addition, our analysis provides new clues as well as research methods for our understanding of population differentiation and natural selection.

  15. Paternal Smoking and Risk of Childhood Acute Lymphoblastic Leukemia: Systematic Review and Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Ruiling Liu

    2011-01-01

    Full Text Available Objective. To investigate the association between paternal smoking and childhood acute lymphoblastic leukemia (ALL. Method. We identified 18 published epidemiologic studies that reported data on both paternal smoking and childhood ALL risk. We performed a meta-analysis and analyzed dose-response relationships on ALL risk for smoking during preconception, during pregnancy, after birth, and ever smoking. Results. The summary odds ratio (OR of childhood ALL associated with paternal smoking was 1.11 (95% Confidence Interval (CI: 1.05–1.18, I2=18% during any time period, 1.25 (95% CI: 1.08–1.46, I2=53% preconception; 1.24 (95% CI: 1.07–1.43, I2=54% during pregnancy, and 1.24 (95% CI: 0.96–1.60, I2=64% after birth, with a dose-response relationship between childhood ALL and paternal smoking preconception or after birth. Conclusion. The evidence supports a positive association between childhood ALL and paternal ever smoking and at each exposure time period examined. Future epidemiologic studies should assess paternal smoking during well-defined exposure windows and should include biomarkers to assess smoking exposure and toxicological mechanisms.

  16. A genome-wide association meta-analysis identifies new childhood obesity loci

    NARCIS (Netherlands)

    Bradfield, Jonathan P.; Taal, H. Rob; Timpson, Nicholas J.; Scherag, Andre; Lecoeur, Cecile; Warrington, Nicole M.; Hypponen, Elina; Holst, Claus; Valcarcel, Beatriz; Thiering, Elisabeth; Salem, Rany M.; Schumacher, Fredrick R.; Cousminer, Diana L.; Sleiman, Patrick M. A.; Zhao, Jianhua; Berkowitz, Robert I.; Vimaleswaran, Karani S.; Jarick, Ivonne; Pennell, Craig E.; Evans, David M.; St Pourcain, Beate; Berry, Diane J.; Mook-Kanamori, Dennis O.; Hofman, Albert; Rivadeneira, Fernando; Uitterlinden, Andre G.; van Duijn, Cornelia M.; van der Valk, Ralf J. P.; de Jongste, Johan C.; Postma, Dirkje S.; Boomsma, Dorret I.; Gauderman, W. James; Hassanein, Mohamed T.; Lindgren, Cecilia M.; Magi, Reedik; Boreham, Colin A. G.; Neville, Charlotte E.; Moreno, Luis A.; Elliott, Paul; Pouta, Anneli; Hartikainen, Anna-Liisa; Li, Mingyao; Raitakari, Olli; Lehtimaki, Terho; Eriksson, Johan G.; Palotie, Aarno; Dallongeville, Jean; Das, Shikta; Deloukas, Panos; McMahon, George; Ring, Susan M.; Kemp, John P.; Buxton, Jessica L.; Blakemore, Alexandra I. F.; Bustamante, Mariona; Guxens, Monica; Hirschhorn, Joel N.; Gillman, Matthew W.; Kreiner-Moller, Eskil; Bisgaard, Hans; Gilliland, Frank D.; Heinrich, Joachim; Wheeler, Eleanor; Barroso, Ines; O'Rahilly, Stephen; Meirhaeghe, Aline; Sorensen, Thorkild I. A.; Power, Chris; Palmer, Lyle J.; Hinney, Anke; Widen, Elisabeth; Farooqi, I. Sadaf; McCarthy, Mark I.; Froguel, Philippe; Meyre, David; Hebebrand, Johannes; Jarvelin, Marjo-Riitta; Jaddoe, Vincent W. V.; Smith, George Davey; Hakonarson, Hakon; Grant, Struan F. A.

    2012-01-01

    Multiple genetic variants have been associated with adult obesity and a few with severe obesity in childhood; however, less progress has been made in establishing genetic influences on common early-onset obesity. We performed a North American, Australian and European collaborative meta-analysis of 1

  17. Meta-analysis of psychological treatments for posttraumatic stress disorder in adult survivors of childhood abuse

    NARCIS (Netherlands)

    Ehring, T.; Welboren, R; Morina, N.; Wicherts, J.M.; Freitag, J.; Emmelkamp, P.M.G.

    2014-01-01

    Posttraumatic stress disorder (PTSD) is highly prevalent in adult survivors of childhood sexual and/or physical abuse. However, intervention studies focusing on this group of patients are underrepresented in earlier meta-analyses on the efficacy of PTSD treatments. The current meta-analysis exclusiv

  18. Childhood poverty and depressive symptoms for older adults in Mexico: a life-course analysis.

    Science.gov (United States)

    Torres, Jacqueline M; Wong, Rebeca

    2013-09-01

    This study applies life-course theories of latent (direct), pathway (indirect) and conditional effects in an analysis of childhood poverty on later-life depressive symptoms among older adults in Mexico. Data are from the 2001 Mexican Health and Aging Study (MHAS), a nationally representative sample of older adults born before 1951 (n = 8696). Respondents had a mean of 3.6 past-week depressive symptoms and 71% had no household sanitation facilities before age 10; this measure served as a proxy for childhood poverty. Childhood poverty is significantly related to scores on an adapted 9-item CES-D scale in the full model (b = 0.27, p poverty reduction and gains in education.

  19. Rapid direct analysis to discriminate geographic origin of extra virgin olive oils by flash gas chromatography electronic nose and chemometrics.

    Science.gov (United States)

    Melucci, Dora; Bendini, Alessandra; Tesini, Federica; Barbieri, Sara; Zappi, Alessandro; Vichi, Stefania; Conte, Lanfranco; Gallina Toschi, Tullia

    2016-08-01

    At present, the geographical origin of extra virgin olive oils can be ensured by documented traceability, although chemical analysis may add information that is useful for possible confirmation. This preliminary study investigated the effectiveness of flash gas chromatography electronic nose and multivariate data analysis to perform rapid screening of commercial extra virgin olive oils characterized by a different geographical origin declared in the label. A comparison with solid phase micro extraction coupled to gas chromatography mass spectrometry was also performed. The new method is suitable to verify the geographic origin of extra virgin olive oils based on principal components analysis and discriminant analysis applied to the volatile profile of the headspace as a fingerprint. The selected variables were suitable in discriminating between "100% Italian" and "non-100% Italian" oils. Partial least squares discriminant analysis also allowed prediction of the degree of membership of unknown samples to the classes examined.

  20. Geographic, technologic, and economic analysis of using reclaimed water for thermoelectric power plant cooling.

    Science.gov (United States)

    Stillwell, Ashlynn S; Webber, Michael E

    2014-04-15

    Use of reclaimed water-municipal wastewater treatment plant effluent-in nonpotable applications can be a sustainable and efficient water management strategy. One such nonpotable application is at thermoelectric power plants since these facilities require cooling, often using large volumes of freshwater. To evaluate the geographic, technologic, and economic feasibility of using reclaimed water to cool thermoelectric power plants, we developed a spatially resolved model of existing power plants. Our model integrates data on power plant and municipal wastewater treatment plant operations into a combined geographic information systems and optimization approach to evaluate the feasibility of cooling system retrofits. We applied this broadly applicable methodology to 125 power plants in Texas as a test case. Results show that sufficient reclaimed water resources exist within 25 miles of 92 power plants (representing 61% of capacity and 50% of generation in our sample), with most of these facilities meeting both short-term and long-term water conservation cost goals. This retrofit analysis indicates that reclaimed water could be a suitable cooling water source for thermoelectric power plants, thereby mitigating some of the freshwater impacts of electricity generation.

  1. Analysis Of Educational Services Distribution-Based Geographic Information System GIS

    Directory of Open Access Journals (Sweden)

    Waleed Lagrab

    2015-03-01

    Full Text Available Abstract This study analyzes the spatial distribution of kindergarten facilities in the study area based on the Geographic Information Systems GIS in order to test an efficiency of GIS technology to redistribute the existing kindergarten and choose the best location in the future and applying the standard criteria for selecting the suitable locations for kindergarten. To achieve this goal the data and information are collected via interviews and comprehensive statistics on the education facilities in Mukalla districts in YEMEN which contributed to building a geographic database for the study area. After that the Kindergarten spatial patterns are analyzed in terms of proximity to each other and used near some other land in the surrounding area such as streets highways factories etc. Also measures the concentration dispersion clustering and distribution direction for the kindergarten this study showed the effectiveness of the GIS for spatial data analysis. One of the most important finding that most of the Kindergarten was established in Mukalla city did not take into account the criteria that set by the authorities. Furthermore almost district suffers from a shortage in the number of kindergarten and pattern of distribution of those kindergartens dominated by spatial dispersed.

  2. Geographical mapping of a multifocal thyroid tumour using genetic alteration analysis & miRNA profiling

    Directory of Open Access Journals (Sweden)

    Li Jing

    2008-12-01

    Full Text Available Abstract Background Papillary thyroid carcinoma (PTC frequently presents as multiple tumour-foci within a single thyroid gland or pluriform, with synchronous tumours comprising different histological variants, raising questions regarding its clonality. Among the genetic aberrations described in PTC, the BRAF V600E mutation and ret/PTC activation occur most commonly. Several studies have investigated the genetic alteration status of multifocal thyroid tumours, with discordant results. To address the question of clonality this study examined disparate geographical and morphological areas from a single PTC (classic PTC, insular and anaplastic foci, and tumour cells adjacent to vascular invasion and lymphocytic infiltrate for the presence of ret/PTC 1 or BRAF mutations. Moreover, we wanted to investigate the consistency of miRNA signatures within disparate areas of a tumour, and geographical data was further correlated with expression profiles of 330 different miRNAs. Putative miRNA gene targets were predicted for differentially regulated miRNAs and immunohistochemistry was performed on tissue sections in an effort to investigate phenotypic variations in microvascular density (MVD, and cytokeratin and p53 protein expression levels. Results All of the morphological areas proved negative for ret/PTC 1 rearrangement. Two distinct foci with classic morphology harboured the BRAF mutation. All other regions, including the insular and anaplastic areas were negative for the mutation. MiRNA profiles were found to distinguish tumours containing the BRAF mutation from the other tumour types, and to differentiate between the more aggressive insular & anaplastic tumours, and the classic variant. Our data corroborated miRNAs previously discovered in this carcinoma, and additional miRNAs linked to various processes involved in tumour growth and proliferation. Conclusion The initial genetic alteration analysis indicated that pluriform PTC did not necessarily evolve

  3. Spatial analysis of childhood cancer: a case/control study.

    Directory of Open Access Journals (Sweden)

    Rebeca Ramis

    Full Text Available Childhood cancer was the leading cause of death among children aged 1-14 years for 2012 in Spain. Leukemia has the highest incidence, followed by tumors of the central nervous system (CNS and lymphomas (Hodgkin lymphoma, HL, and Non-Hodgkin's lymphoma, NHL. Spatial distribution of childhood cancer cases has been under concern with the aim of identifying potential risk factors.The two objectives are to study overall spatial clustering and cluster detection of cases of the three main childhood cancer causes, looking to increase etiological knowledge.We ran a case-control study. The cases were children aged 0 to 14 diagnosed with leukemia, lymphomas (HL and NHL or CNS neoplasm in five Spanish regions for the period 1996-2011. As a control group, we used a sample from the Birth Registry matching every case by year of birth, autonomous region of residence and sex with six controls. We geocoded and validated the address of the cases and controls. For our two objectives we used two different methodologies. For the first, for overall spatial clustering detection, we used the differences of K functions from the spatial point patterns perspective proposed by Diggle and Chetwynd and the second, for cluster detection, we used the spatial scan statistic proposed by Kulldorff with a level for statistical significance of 0.05.We had 1062 cases of leukemia, 714 cases of CNS, 92 of HL and 246 of NHL. Accordingly we had 6 times the number of controls, 6372 controls for leukemia, 4284 controls for CNS, 552 controls for HL and 1476 controls for NHL. We found variations in the estimated empirical D(s for the different regions and cancers, including some overall spatial clustering for specific regions and distances. We did not find statistically significant clusters.The variations in the estimated empirical D(s for the different regions and cancers could be partially explained by the differences in the spatial distribution of the population; however, according to the

  4. Spatial analysis spotlighting early childhood leprosy transmission in a hyperendemic municipality of the Brazilian Amazon region.

    Directory of Open Access Journals (Sweden)

    Josafá Gonçalves Barreto

    2014-02-01

    Full Text Available BACKGROUND: More than 200,000 new cases of leprosy were reported by 105 countries in 2011. The disease is a public health problem in Brazil, particularly within high-burden pockets in the Amazon region where leprosy is hyperendemic among children. METHODOLOGY: We applied geographic information systems and spatial analysis to determine the spatio-temporal pattern of leprosy cases in a hyperendemic municipality of the Brazilian Amazon region (Castanhal. Moreover, we performed active surveillance to collect clinical, epidemiological and serological data of the household contacts of people affected by leprosy and school children in the general population. The occurrence of subclinical infection and overt disease among the evaluated individuals was correlated with the spatio-temporal pattern of leprosy. PRINCIPAL FINDINGS: The pattern of leprosy cases showed significant spatio-temporal heterogeneity (p<0.01. Considering 499 mapped cases, we found spatial clusters of high and low detection rates and spatial autocorrelation of individual cases at fine spatio-temporal scales. The relative risk of contracting leprosy in one specific cluster with a high detection rate is almost four times the risk in the areas of low detection rate (RR = 3.86; 95% CI = 2.26-6.59; p<0.0001. Eight new cases were detected among 302 evaluated household contacts: two living in areas of clusters of high detection rate and six in hyperendemic census tracts. Of 188 examined students, 134 (71.3% lived in hyperendemic areas, 120 (63.8% were dwelling less than 100 meters of at least one reported leprosy case, 125 (66.5% showed immunological evidence (positive anti-PGL-I IgM titer of subclinical infection, and 9 (4.8% were diagnosed with leprosy (8 within 200 meters of a case living in the same area. CONCLUSIONS/SIGNIFICANCE: Spatial analysis provided a better understanding of the high rate of early childhood leprosy transmission in this region. These findings can be applied to guide

  5. Development of Ethnic, Racial, and National Prejudice in Childhood and Adolescence: A Multinational Meta-Analysis of Age Differences

    Science.gov (United States)

    Raabe, Tobias; Beelmann, Andreas

    2011-01-01

    This meta-analysis summarizes 113 research reports worldwide (121 cross-sectional and 7 longitudinal studies) on age differences in ethnic, racial, or national prejudice among children and adolescents. Overall, results indicated a peak in prejudice in middle childhood (5-7 years) followed by a slight decrease until late childhood (8-10 years). In…

  6. Geographic Distribution of Leishmania Species in Ecuador Based on the Cytochrome B Gene Sequence Analysis.

    Science.gov (United States)

    Kato, Hirotomo; Gomez, Eduardo A; Martini-Robles, Luiggi; Muzzio, Jenny; Velez, Lenin; Calvopiña, Manuel; Romero-Alvarez, Daniel; Mimori, Tatsuyuki; Uezato, Hiroshi; Hashiguchi, Yoshihisa

    2016-07-01

    A countrywide epidemiological study was performed to elucidate the current geographic distribution of causative species of cutaneous leishmaniasis (CL) in Ecuador by using FTA card-spotted samples and smear slides as DNA sources. Putative Leishmania in 165 samples collected from patients with CL in 16 provinces of Ecuador were examined at the species level based on the cytochrome b gene sequence analysis. Of these, 125 samples were successfully identified as Leishmania (Viannia) guyanensis, L. (V.) braziliensis, L. (V.) naiffi, L. (V.) lainsoni, and L. (Leishmania) mexicana. Two dominant species, L. (V.) guyanensis and L. (V.) braziliensis, were widely distributed in Pacific coast subtropical and Amazonian tropical areas, respectively. Recently reported L. (V.) naiffi and L. (V.) lainsoni were identified in Amazonian areas, and L. (L.) mexicana was identified in an Andean highland area. Importantly, the present study demonstrated that cases of L. (V.) braziliensis infection are increasing in Pacific coast areas.

  7. Impact of proximity-adjusted preferences on rank-order stability in geographical multicriteria decision analysis

    Science.gov (United States)

    Ligmann-Zielinska, Arika; Jankowski, Piotr

    2012-04-01

    This paper presents a new approach to deriving preferences assigned to evaluation criteria in geographical multicriteria decision analysis. In this approach, the preferences, expressed by numeric weights, are adjusted by distance measures derived from the explicit consideration of a locational structure. The structure is given by locations of decision options and high importance reference objects. The approach is demonstrated on the example of a house selection case study in San Diego, California. The results show that proximity-adjusted preferences for the evaluation criteria can alter significantly the rank order of decision options. Consequently, the explicit modeling of spatial preference variability may be needed in order to better account for decision-maker's preferences.

  8. The most controversial topics in Wikipedia: A multilingual and geographical analysis

    CERN Document Server

    Yasseri, Taha; Graham, Mark; Kertész, János

    2013-01-01

    We present, visualize and analyse the similarities and differences between the controversial topics related to "edit wars" identified in 10 different language versions of Wikipedia. After a brief review of the related work we describe the methods developed to locate, measure, and categorize the controversial topics in the different languages. Visualizations of the degree of overlap between the top 100 list of most controversial articles in different languages and the content related geographical locations will be presented. We discuss what the presented analysis and visualizations can tell us about the multicultural aspects of Wikipedia, and, in general, about cultures of peer-production with focus on universal and specifically, local features. We demonstrate that Wikipedia is more than just an encyclopaedia; it is also a window into divergent social-spatial priorities, interests and preferences.

  9. How geographical information systems analysis influences the continuum of patient care.

    Science.gov (United States)

    Pliskie, Jennifer; Wallenfang, Laura

    2014-01-01

    As the vast repository of data about millions of patients grows, the analysis of this information is changing the provider-patient relationship and influencing the continuum of care for broad swaths of the population. At the same time, while population health management moves from a volume-based model to a value-based one and additional patients seek care due to healthcare reform, hospitals and healthcare networks are evaluating their business models and searching for new revenue streams. Utilizing geographical information systems to model and analyze large amounts of data is helping organizations better understand the characteristics of their patient population, demographic and socioeconomic trends, and shifts in the utilization of healthcare. In turn, organizations can more effectively conduct service line planning, strategic business plans, market growth strategies, and human resource planning. Healthcare organizations that use GIS modeling can set themselves apart by making more informed and objective business strategy decisions.

  10. Geographic Distribution of Leishmania Species in Ecuador Based on the Cytochrome B Gene Sequence Analysis

    Science.gov (United States)

    Kato, Hirotomo; Gomez, Eduardo A.; Martini-Robles, Luiggi; Muzzio, Jenny; Velez, Lenin; Calvopiña, Manuel; Romero-Alvarez, Daniel; Mimori, Tatsuyuki; Uezato, Hiroshi; Hashiguchi, Yoshihisa

    2016-01-01

    A countrywide epidemiological study was performed to elucidate the current geographic distribution of causative species of cutaneous leishmaniasis (CL) in Ecuador by using FTA card-spotted samples and smear slides as DNA sources. Putative Leishmania in 165 samples collected from patients with CL in 16 provinces of Ecuador were examined at the species level based on the cytochrome b gene sequence analysis. Of these, 125 samples were successfully identified as Leishmania (Viannia) guyanensis, L. (V.) braziliensis, L. (V.) naiffi, L. (V.) lainsoni, and L. (Leishmania) mexicana. Two dominant species, L. (V.) guyanensis and L. (V.) braziliensis, were widely distributed in Pacific coast subtropical and Amazonian tropical areas, respectively. Recently reported L. (V.) naiffi and L. (V.) lainsoni were identified in Amazonian areas, and L. (L.) mexicana was identified in an Andean highland area. Importantly, the present study demonstrated that cases of L. (V.) braziliensis infection are increasing in Pacific coast areas. PMID:27410039

  11. Detrended fluctuation analysis of daily temperature records: Geographic dependence over Australia

    CERN Document Server

    Kir'aly, A; Kir\\'aly, Andrea; J\\'anosi, Imre M.

    2004-01-01

    Daily temperature anomaly records are analyzed (61 for Australia, 18 for Hungary) by means of detrended fluctuation analysis. Positive long range asymptotic correlations extending up to 5-10 years are detected for each case. Contrary to earlier claims, the correlation exponent is not universal for continental stations. Interestingly, the dominant factor is geographic latitude over Australia: the general tendency is a decrease of correlation exponent with increasing distance from the equator. This tendency is in a complete agreement with the results found by Tsonis et al. (1999) for 500-hPa height anomalies in the northern hemisphere. The variance of fluctuations exhibits an opposite trend, the larger is the distance from the equator, the larger the amplitude of intrinsic fluctuations. The presence of Tropospheric Biennial Oscillation is clearly identified for three stations at the north-eastern edge of the Australian continent.

  12. Geographic information analysis: An ecological approach for the management of wildlife on the forest landscape

    Science.gov (United States)

    Ripple, William J.

    1995-01-01

    This document is a summary of the project funded by NAGw-1460 as part of the Earth Observation Commericalization/Applications Program (EOCAP) directed by NASA's Earth Science and Applications Division. The goal was to work with several agencies to focus on forest structure and landscape characterizations for wildlife habitat applications. New analysis techniques were used in remote sensing and landscape ecology with geographic information systems (GIS). The development of GIS and the emergence of the discipline of landscape ecology provided us with an opportunity to study forest and wildlife habitat resources from a new perspective. New techniques were developed to measure forest structure across scales from the canopy to the regional level. This paper describes the project team, technical advances, and technology adoption process that was used. Reprints of related refereed journal articles are in the Appendix.

  13. A Meta-Analysis for Association of Maternal Smoking with Childhood Refractive Error and Amblyopia.

    Science.gov (United States)

    Li, Li; Qi, Ya; Shi, Wei; Wang, Yuan; Liu, Wen; Hu, Man

    2016-01-01

    Background. We aimed to evaluate the association between maternal smoking and the occurrence of childhood refractive error and amblyopia. Methods. Relevant articles were identified from PubMed and EMBASE up to May 2015. Combined odds ratio (OR) corresponding with its 95% confidence interval (CI) was calculated to evaluate the influence of maternal smoking on childhood refractive error and amblyopia. The heterogeneity was evaluated with the Chi-square-based Q statistic and the I (2) test. Potential publication bias was finally examined by Egger's test. Results. A total of 9 articles were included in this meta-analysis. The pooled OR showed that there was no significant association between maternal smoking and childhood refractive error. However, children whose mother smoked during pregnancy were 1.47 (95% CI: 1.12-1.93) times and 1.43 (95% CI: 1.23-1.66) times more likely to suffer from amblyopia and hyperopia, respectively, compared with children whose mother did not smoke, and the difference was significant. Significant heterogeneity was only found among studies involving the influence of maternal smoking on children's refractive error (P analysis suggests that maternal smoking is a risk factor for childhood hyperopia and amblyopia.

  14. A genome-wide association meta-analysis identifies new childhood obesity loci

    DEFF Research Database (Denmark)

    Bradfield, Jonathan P; Taal, H Rob; Timpson, Nicholas J

    2012-01-01

    Multiple genetic variants have been associated with adult obesity and a few with severe obesity in childhood; however, less progress has been made in establishing genetic influences on common early-onset obesity. We performed a North American, Australian and European collaborative meta-analysis o......-analysis of 14 studies consisting of 5,530 cases (≥95th percentile of body mass index (BMI)) and 8,318 controls (...

  15. Effect of Climate Factors on the Childhood Pneumonia in Papua New Guinea: A Time-Series Analysis

    OpenAIRE

    Jinseob Kim; Jong-Hun Kim; Hae-Kwan Cheong; Ho Kim; Yasushi Honda; Mina Ha; Masahiro Hashizume; Joel Kolam; Kasis Inape

    2016-01-01

    This study aimed to assess the association between climate factors and the incidence of childhood pneumonia in Papua New Guinea quantitatively and to evaluate the variability of the effect size according to their geographic properties. The pneumonia incidence in children under five-year and meteorological factors were obtained from six areas, including monthly rainfall and the monthly average daily maximum temperatures during the period from 1997 to 2006 from national health surveillance data...

  16. Identification of geographically distributed sub-populations of Leishmania (Leishmania major by microsatellite analysis

    Directory of Open Access Journals (Sweden)

    Schwenkenbecher Jan

    2008-06-01

    Full Text Available Abstract Background Leishmania (Leishmania major, one of the agents causing cutaneous leishmaniasis (CL in humans, is widely distributed in the Old World where different species of wild rodent and phlebotomine sand fly serve as animal reservoir hosts and vectors, respectively. Despite this, strains of L. (L. major isolated from many different sources over many years have proved to be relatively uniform. To investigate the population structure of the species highly polymorphic microsatellite markers were employed for greater discrimination among it's otherwise closely related strains, an approach applied successfully to other species of Leishmania. Results Multilocus Microsatellite Typing (MLMT based on 10 different microsatellite markers was applied to 106 strains of L. (L. major from different regions where it is endemic. On applying a Bayesian model-based approach, three main populations were identified, corresponding to three separate geographical regions: Central Asia (CA; the Middle East (ME; and Africa (AF. This was congruent with phylogenetic reconstructions based on genetic distances. Re-analysis separated each of the populations into two sub-populations. The two African sub-populations did not correlate well with strains' geographical origin. Strains falling into the sub-populations CA and ME did mostly group according to their place of isolation although some anomalies were seen, probably, owing to human migration. Conclusion The model- and distance-based analyses of the microsatellite data exposed three main populations of L. (L. major, Central Asia, the Middle East and Africa, each of which separated into two sub-populations. This probably correlates with the different species of rodent host.

  17. Geographic Names

    Data.gov (United States)

    Minnesota Department of Natural Resources — The Geographic Names Information System (GNIS), developed by the United States Geological Survey in cooperation with the U.S. Board of Geographic Names, provides...

  18. Community violence and urban childhood asthma: a multilevel analysis.

    Science.gov (United States)

    Sternthal, M J; Jun, H-J; Earls, F; Wright, R J

    2010-12-01

    We examined the association between community violence exposure and childhood asthma risk in a multilevel, multimethod, longitudinal study controlling for individual- and neighbourhood-level confounders and pathway variables. Analyses included 2,071 children aged 0-9 yrs at enrolment from the Project on Human Development in Chicago Neighborhoods. Multilevel logistic regression models estimated the likelihood of asthma, controlling for individual-level (child's age, sex, race/ethnicity, maternal asthma, socioeconomic status and family violence in the home) and neighbourhood-level confounders (concentrated disadvantage, collective efficacy and social disorder), and pathway variables (maternal smoking, breastfeeding). In adjusted analyses, medium (OR 1.60, 95% CI 1.17-2.19) and high levels (OR 1.56, 95% CI 1.12-2.18) of community violence were associated with increased asthma risk, relative to low levels. The increased asthma risk remained for African Americans when models included community violence and all other individual-level covariates, but attenuated to borderline nonsignificance when further adjusting for collective efficacy. Community violence is associated with asthma risk when controlling for individual- and neighborhood-level confounders. Neither community violence, nor the other individual-level factors, fully accounted for the excess asthma burden among African Americans. These data suggest that public health interventions outside the biomedical model may be needed to reduce asthma in disadvantaged populations.

  19. Development and implementation of a low cost micro computer system for LANDSAT analysis and geographic data base applications

    Science.gov (United States)

    Faust, N.; Jordon, L.

    1981-01-01

    Since the implementation of the GRID and IMGRID computer programs for multivariate spatial analysis in the early 1970's, geographic data analysis subsequently moved from large computers to minicomputers and now to microcomputers with radical reduction in the costs associated with planning analyses. Programs designed to process LANDSAT data to be used as one element in a geographic data base were used once NIMGRID (new IMGRID), a raster oriented geographic information system, was implemented on the microcomputer. Programs for training field selection, supervised and unsupervised classification, and image enhancement were added. Enhancements to the color graphics capabilities of the microsystem allow display of three channels of LANDSAT data in color infrared format. The basic microcomputer hardware needed to perform NIMGRID and most LANDSAT analyses is listed as well as the software available for LANDSAT processing.

  20. Color quality of pigments in cochineals (Dactylopius coccus Costa). Geographical origin characterization using multivariate statistical analysis.

    Science.gov (United States)

    Méndez, Jesús; González, Mónica; Lobo, M Gloria; Carnero, Aurelio

    2004-03-10

    The commercial value of a cochineal (Dactylopius coccus Costa) sample is associated with its color quality. Because the cochineal is a legal food colorant, its color quality is generally understood as its pigment content. Simply put, the higher this content, the more valuable the sample is to the market. In an effort to devise a way to measure the color quality of a cochineal, the present study evaluates different parameters of color measurement such as chromatic attributes (L*, and a*), percentage of carminic acid, tint determination, and chromatographic profile of pigments. Tint determination did not achieve this objective because this parameter does not correlate with carminic acid content. On the other hand, carminic acid showed a highly significant correlation (r = - 0.922, p = 0.000) with L* values determined from powdered cochineal samples. The combination of the information from the spectrophotometric determination of carminic acid with that of the pigment profile acquired by liquid chromatography (LC) and the composition of the red and yellow pigment groups, also acquired by LC, enables greater accuracy in judging the quality of the final sample. As a result of this study, it was possible to achieve the separation of cochineal samples according to geographical origin using two statistical techniques: cluster analysis and principal component analysis.

  1. Improving land cover classification using input variables derived from a geographically weighted principal components analysis

    Science.gov (United States)

    Comber, Alexis J.; Harris, Paul; Tsutsumida, Narumasa

    2016-09-01

    This study demonstrates the use of a geographically weighted principal components analysis (GWPCA) of remote sensing imagery to improve land cover classification accuracy. A principal components analysis (PCA) is commonly applied in remote sensing but generates global, spatially-invariant results. GWPCA is a local adaptation of PCA that locally transforms the image data, and in doing so, can describe spatial change in the structure of the multi-band imagery, thus directly reflecting that many landscape processes are spatially heterogenic. In this research the GWPCA localised loadings of MODIS data are used as textural inputs, along with GWPCA localised ranked scores and the image bands themselves to three supervised classification algorithms. Using a reference data set for land cover to the west of Jakarta, Indonesia the classification procedure was assessed via training and validation data splits of 80/20, repeated 100 times. For each classification algorithm, the inclusion of the GWPCA loadings data was found to significantly improve classification accuracy. Further, but more moderate improvements in accuracy were found by additionally including GWPCA ranked scores as textural inputs, data that provide information on spatial anomalies in the imagery. The critical importance of considering both spatial structure and spatial anomalies of the imagery in the classification is discussed, together with the transferability of the new method to other studies. Research topics for method refinement are also suggested.

  2. Petrophysical Analysis and Geographic Information System for San Juan Basin Tight Gas Reservoirs

    Energy Technology Data Exchange (ETDEWEB)

    Martha Cather; Robert Lee; Robert Balch; Tom Engler; Roger Ruan; Shaojie Ma

    2008-10-01

    The primary goal of this project is to increase the availability and ease of access to critical data on the Mesaverde and Dakota tight gas reservoirs of the San Juan Basin. Secondary goals include tuning well log interpretations through integration of core, water chemistry and production analysis data to help identify bypassed pay zones; increased knowledge of permeability ratios and how they affect well drainage and thus infill drilling plans; improved time-depth correlations through regional mapping of sonic logs; and improved understanding of the variability of formation waters within the basin through spatial analysis of water chemistry data. The project will collect, integrate, and analyze a variety of petrophysical and well data concerning the Mesaverde and Dakota reservoirs of the San Juan Basin, with particular emphasis on data available in the areas defined as tight gas areas for purpose of FERC. A relational, geo-referenced database (a geographic information system, or GIS) will be created to archive this data. The information will be analyzed using neural networks, kriging, and other statistical interpolation/extrapolation techniques to fine-tune regional well log interpretations, improve pay zone recognition from old logs or cased-hole logs, determine permeability ratios, and also to analyze water chemistries and compatibilities within the study area. This single-phase project will be accomplished through four major tasks: Data Collection, Data Integration, Data Analysis, and User Interface Design. Data will be extracted from existing databases as well as paper records, then cleaned and integrated into a single GIS database. Once the data warehouse is built, several methods of data analysis will be used both to improve pay zone recognition in single wells, and to extrapolate a variety of petrophysical properties on a regional basis. A user interface will provide tools to make the data and results of the study accessible and useful. The final deliverable

  3. Alternative health care consultations in Ontario, Canada: A geographic and socio-demographic analysis

    Directory of Open Access Journals (Sweden)

    Eby Jeanette

    2011-06-01

    Full Text Available Abstract Background An important but understudied component of Canada's health system is alternative care. The objective of this paper is to examine the geographic and socio-demographic characteristics of alternative care consultation in Ontario, Canada's largest province. Methods Data is drawn from the Canadian Community Health Survey (CCHS Cycle 3.1, 2005 for people aged 18 or over (n = 32,598 who had a consultation with an alternative health care provider. Four groups of consultations are examined: (1 all consultations (2 massage therapy (3 acupuncture, and (4 homeopath/naturopath. Descriptive statistics, mapping and logistic regression modeling are employed to analyze the data and to compare modalities of alternative health care use. Results In 2005, more than 1.2 million adults aged 18 or over consulted an alternative health care provider, representing about 13% of the total population of Ontario. The analysis revealed a varied geographic pattern of consultations across the province. Consultations were fairly even across the urban to rural continuum and rural residents were just as likely to consult a provider as their urban counterparts. From a health perspective, people with a chronic condition, lower health status and self-perceived unmet health care needs were more likely to see an alternative health provider. Women with chronic conditions such as fibromyalgia, high blood pressure, chronic fatigue syndrome and chemical sensitivities were more likely to see an alternative provider if they felt their health care needs were not being met. Conclusions The analysis revealed that geography is not a factor in determining alternative health care consultations in Ontario. By contrast, there is a strong association between these consultations and socio-demographic characteristics particularly age, sex, education, health and self-perceived unmet health care needs. The results underscore the importance of women's health needs as related to

  4. Predicting adult obesity from childhood obesity: a systematic review and meta-analysis.

    Science.gov (United States)

    Simmonds, M; Llewellyn, A; Owen, C G; Woolacott, N

    2016-02-01

    A systematic review and meta-analysis was performed to investigate the ability of simple measures of childhood obesity such as body mass index (BMI) to predict future obesity in adolescence and adulthood. Large cohort studies, which measured obesity both in childhood and in later adolescence or adulthood, using any recognized measure of obesity were sought. Study quality was assessed. Studies were pooled using diagnostic meta-analysis methods. Fifteen prospective cohort studies were included in the meta-analysis. BMI was the only measure of obesity reported in any study, with 200,777 participants followed up. Obese children and adolescents were around five times more likely to be obese in adulthood than those who were not obese. Around 55% of obese children go on to be obese in adolescence, around 80% of obese adolescents will still be obese in adulthood and around 70% will be obese over age 30. Therefore, action to reduce and prevent obesity in these adolescents is needed. However, 70% of obese adults were not obese in childhood or adolescence, so targeting obesity reduction solely at obese or overweight children needs to be considered carefully as this may not substantially reduce the overall burden of adult obesity.

  5. Genetic and antigenic analysis of Babesia bigemina isolates from five geographical regions of Brazil

    Directory of Open Access Journals (Sweden)

    Madruga Claudio R.

    2002-01-01

    Full Text Available A molecular epidemiological study was performed with Babesia bigemina isolates from five geographical regions of Brazil. The genetic analysis was done with random amplification of polymorphic DNA (RAPD, repetitive extragenic palindromic elements-polymerase chain reaction (REP-PCR and enterobacterial repetitive intergenic consensus sequences-polymerase chain reaction (ERIC-PCR that showed genetic polymorphism between these isolates and generated fingerprinting. In RAPD, ILO872 and ILO876 primers were able to detect at least one fingerprinting for each B. bigemina isolate. The amplification of B. bigemina DNA fragments by REP-PCR and ERIC-PCR gave evidence for the presence in this haemoprotozoan of the sequences described previously in microorganisms of the bacterial kingdom. For the first time it was demonstrated that both techniques can be used for genetic analysis of a protozoan parasite, although the ERIC-PCR was more discriminatory than REP-PCR. The dendogram with similarity coefficient among isolates showed two clusters and one subcluster. The Northeastern and Mid-Western isolates showed the greatest genetic diversity, while the Southeastern and Southern isolates were the closest. The antigenic analysis was done through indirect fluorescent antibody technique and Western blotting using a panel of monoclonal antibodies directed against epitopes on the merozoite membrane surface, rhoptries and membrane of infected erythrocytes. As expected, the merozoite variable surface antigens, major surface antigen (MSA-1 and MSA-2 showed antigenic diversity. However, B cell epitopes on rhoptries and infected erythrocytes were conserved among all isolates studied. In this study it was possible to identify variable and conserved antigens, which had already been described as potential immunogens. Considering that an attenuated Babesia clone used as immunogen selected populations capable of evading the immunity induced by this vaccine, it is necessary to

  6. A GEOGRAPHIC ANALYSIS OF OPTIMAL SIGNAGE LOCATION SELECTION IN SCENIC AREA

    Directory of Open Access Journals (Sweden)

    L. Ruan

    2016-06-01

    Full Text Available As an important part of the scenic area infrastructure services, signage guiding system plays an indispensable role in guiding the way and improving the quality of tourism experience. This paper proposes an optimal method in signage location selection and direction content design in a scenic area based on geographic analysis. The object of the research is to provide a best solution to arrange limited guiding boards in a tourism area to show ways arriving at any scenic spot from any entrance. There are four steps to achieve the research object. First, the spatial distribution of the junction of the scenic road, the passageway and the scenic spots is analyzed. Then, the count of scenic roads intersection on the shortest path between all entrances and all scenic spots is calculated. Next, combing with the grade of the scenic road and scenic spots, the importance of each road intersection is estimated quantitatively. Finally, according to the importance of all road intersections, the most suitable layout locations of signage guiding boards can be provided. In addition, the method is applied in the Ming Tomb scenic area in China and the result is compared with the existing signage guiding space layout.

  7. a Geographic Analysis of Optimal Signage Location Selection in Scenic Area

    Science.gov (United States)

    Ruan, Ling; Long, Ying; Zhang, Ling; Wu, Xiao Ling

    2016-06-01

    As an important part of the scenic area infrastructure services, signage guiding system plays an indispensable role in guiding the way and improving the quality of tourism experience. This paper proposes an optimal method in signage location selection and direction content design in a scenic area based on geographic analysis. The object of the research is to provide a best solution to arrange limited guiding boards in a tourism area to show ways arriving at any scenic spot from any entrance. There are four steps to achieve the research object. First, the spatial distribution of the junction of the scenic road, the passageway and the scenic spots is analyzed. Then, the count of scenic roads intersection on the shortest path between all entrances and all scenic spots is calculated. Next, combing with the grade of the scenic road and scenic spots, the importance of each road intersection is estimated quantitatively. Finally, according to the importance of all road intersections, the most suitable layout locations of signage guiding boards can be provided. In addition, the method is applied in the Ming Tomb scenic area in China and the result is compared with the existing signage guiding space layout.

  8. Spatial analysis of lettuce downy mildew using geostatistics and geographic information systems.

    Science.gov (United States)

    Wu, B M; van Bruggen, A H; Subbarao, K V; Pennings, G G

    2001-02-01

    ABSTRACT The epidemiology of lettuce downy mildew has been investigated extensively in coastal California. However, the spatial patterns of the disease and the distance that Bremia lactucae spores can be transported have not been determined. During 1995 to 1998, we conducted several field- and valley-scale surveys to determine spatial patterns of this disease in the Salinas valley. Geostatistical analyses of the survey data at both scales showed that the influence range of downy mildew incidence at one location on incidence at other locations was between 80 and 3,000 m. A linear relationship was detected between semivariance and lag distance at the field scale, although no single statistical model could fit the semi-variograms at the valley scale. Spatial interpolation by the inverse distance weighting method with a power of 2 resulted in plausible estimates of incidence throughout the valley. Cluster analysis in geographic information systems on the interpolated disease incidence from different dates demonstrated that the Salinas valley could be divided into two areas, north and south of Salinas City, with high and low disease pressure, respectively. Seasonal and spatial trends along the valley suggested that the distinction between the downy mildew conducive and nonconducive areas might be determined by environmental factors.

  9. Environmental factor analysis of cholera in China using remote sensing and geographical information systems.

    Science.gov (United States)

    Xu, M; Cao, C X; Wang, D C; Kan, B; Xu, Y F; Ni, X L; Zhu, Z C

    2016-04-01

    Cholera is one of a number of infectious diseases that appears to be influenced by climate, geography and other natural environments. This study analysed the environmental factors of the spatial distribution of cholera in China. It shows that temperature, precipitation, elevation, and distance to the coastline have significant impact on the distribution of cholera. It also reveals the oceanic environmental factors associated with cholera in Zhejiang, which is a coastal province of China, using both remote sensing (RS) and geographical information systems (GIS). The analysis has validated the correlation between indirect satellite measurements of sea surface temperature (SST), sea surface height (SSH) and ocean chlorophyll concentration (OCC) and the local number of cholera cases based on 8-year monthly data from 2001 to 2008. The results show the number of cholera cases has been strongly affected by the variables of SST, SSH and OCC. Utilizing this information, a cholera prediction model has been established based on the oceanic and climatic environmental factors. The model indicates that RS and GIS have great potential for designing an early warning system for cholera.

  10. Ontology-based analysis of multi-scale modeling of geographical features

    Institute of Scientific and Technical Information of China (English)

    WANG; Yanhui; LI; Xiaojuan; GONG; Huili

    2006-01-01

    As multi-scale databases based on scale series of map data are built, conceptual models are needed to define proper multi-scale representation formulas and to extract model entities and the relationships among them. However, the results of multi-scale conceptual abstraction schema may differ, according to which cognition, abstraction and application views are utilized, which presents an obvious obstacle to the reuse and sharing of spatial data. To facilitate the design of unified, common and objective abstract schema views for multi-scale spatial databases, this paper proposes an ontology-based analysis method for the multi-scale modeling of geographical features. It includes a three-layer ontology model, which serves as the framework for common multi-scale abstraction schema; an explanation of formulary abstractions accompanied by definitions of entities and their relationships at the same scale, as well as different scales,which are meant to provide strong feasibility, expansibility and speciality functions; and a case in point involving multi-scale representations of road features, to verify the method's feasibility.

  11. Integrated geographic information systems (IGIS) analysis and definition of the tectonic framework of northern Mexico

    Science.gov (United States)

    Martinez Pina, Carlos Manuel

    Crustal rupture structures reactivated in the course of the tectonic history of northern Mexico are the surface expressions of planes of weakness, in the form of simple or composite rectilinear features or slightly curved, defined as lineaments. Unless otherwise defined as strike-slip faults, lineaments are part of parallel and sub-parallel oblique convergent or oblique divergent tectonic zones cross cutting the Sierra Madre Occidental and northern Mexico, in a NW trend. These shear zones are the response to the oblique subduction of the Farallon plate beneath North America. Kinematic analysis of five selected sites in northern Mexico, three basins and two compressional shear zones, proved possible a combination of shear mechanism diagram and models from analogue materials, with satellite imagery and geographic information systems, as an aid to define strike-slip fault motion. This was done using a reverse engineering process by comparing geometries. One of the sites assessed, involving the Parras Basin, Coahuila Block (CB), San Marcos fault, a postulated PBF-1 fault, allowed for palinpastic reconstruction of the CB that corroborated the results of the vector motion defined, in addition to an extension of ˜25% in a northwest southeast direction. A GIS-based compilation and georeferenced regional structural studies by several researchers were used as ground control areas (GCA); their interpolation and interpretation, resulted in a tectonic framework map of northern Mexico. In addition, shaded relief models overlaid by the lineaments / fault layer allowed structural analyses of basins related to these major structures. Two important results were obtained from this study: the Tepehuanes-San Luis-fault (TSL) and the Guadalupe fault, named herein, displaces the Villa de Reyes graben, and the Aguascalientes graben, respectively, to the SE, confirming their left lateral vector motion; afterwards TSL was displaced south by the right lateral strike slip Taxco-San Miguel de

  12. Interventions for Childhood Obesity Control in Cyprus: An analysis and Evaluation of Programmes and Protocols

    Directory of Open Access Journals (Sweden)

    Georgianna Joseph

    2013-01-01

    Full Text Available In the last twenty years, there has been an increase in the prevalence of obesity with a simultaneous increase in chronic diseases.Aim: The aim of this literature review is to discuss available interventions for childhood obesity (2-11 years and to propose effective prevention policies for the Republic of Cyprus.Methods: Childhood obesity prevention and intervention programs in Cyprus were analysed using SWOT analysis and evaluation protocols for compatibility and sustainability among health professionals andgovernment partners.Results: The preliminary literature review reveals that there are specific short comings with regards to the existing NHS and public health. The sustainability of existing health policies and implemented programs is questionable as there are no coherent monitoring systems in place. There are many worthwhile programsand organizations that are often delayed due to conflict of interest.Conclusions: Analysis shows that the implementation, via a Cypriot National Health System, of public health strategies could be effective means of addressing specifically childhood obesity. This includes a more active role for the family physician and policies of a multi- level strategy, aiming as fostering innovative public-private healthcare collaborations, supported by educational institutions, infrastructure, legislation and the wider society.However, such strategies are needed on a long-term basis and throughout a person’s life span.

  13. Implementation of Hierarchical Task Analysis for User Interface Design in Drawing Application for Early Childhood Education

    Directory of Open Access Journals (Sweden)

    Mira Kania Sabariah

    2016-05-01

    Full Text Available Draw learning in early childhood is an important lesson and full of stimulation of the process of growth and development of children which could help to train the fine motor skills. We have had a lot of applications that can be used to perform learning, including interactive learning applications. Referring to the observations that have been conducted showed that the experiences given by the applications that exist today are very diverse and have not been able to represent the model of learning and characteristics of early childhood (4-6 years. Based on the results, Hierarchical Task Analysis method generated a list of tasks that must be done in designing an user interface that represents the user experience in draw learning. Then by using the Heuristic Evaluation method the usability of the model has fulfilled a very good level of understanding and also it can be enhanced and produce a better model.

  14. Designing a web-based learning portal for geographic visualization and analysis in public health.

    Science.gov (United States)

    Robinson, Anthony C; MacEachren, Alan M; Roth, Robert E

    2011-09-01

    Interactive mapping and spatial analysis tools are under-utilized by health researchers and decision-makers as a result of scarce training materials, few examples demonstrating the successful use of geographic visualization, and poor mechanisms for sharing results generated by geovisualization. Here, we report on the development of the Geovisual EXplication(G-EX) Portal, a web-based application designed to connect researchers in geovisualization and related mapping sciences, to users who are working in public health and epidemiology. This paper focuses on the design and development of the G-EX Portal Learn module, a set of tools intended to disseminate learning artifacts. Initial design and development of the G-EX Portal has been guided by our past research on the use and usability of geovisualization in public health. As part of the iterative design and development process, we conducted a needs assessment survey with targeted end-users, which we report on here. The survey focused on users' current learning habits, their preferred kind of learning artifacts and issues they may have with contributing learning artifacts to web portals. Survey results showed that users desire a diverse set of learning artifacts in terms of both formats and topics covered. Results also revealed a willingness of users to contribute both learning artifacts and personal information that would help other users to evaluate the credibility of the learning artifact source. We include a detailed description of the G-EX Portal Learn module and focus on modifications to the design of the Learn module as a result from feedback we received from our survey.

  15. Meta-analysis of psychological treatments for posttraumatic stress disorder in adult survivors of childhood abuse.

    Science.gov (United States)

    Ehring, Thomas; Welboren, Renate; Morina, Nexhmedin; Wicherts, Jelte M; Freitag, Janina; Emmelkamp, Paul M G

    2014-12-01

    Posttraumatic stress disorder (PTSD) is highly prevalent in adult survivors of childhood sexual and/or physical abuse. However, intervention studies focusing on this group of patients are underrepresented in earlier meta-analyses on the efficacy of PTSD treatments. The current meta-analysis exclusively focused on studies evaluating the efficacy of psychological interventions for PTSD in adult survivors of childhood abuse. Sixteen randomized controlled trials meeting inclusion criteria could be identified that were subdivided into trauma-focused cognitive behavior therapy (CBT), non-trauma-focused CBT, eye movement desensitization and reprocessing, and other treatments (interpersonal, emotion-focused). Results showed that psychological interventions are efficacious for PTSD in adult survivors of childhood abuse, with an aggregated uncontrolled effect size of g=1.24 (pre- vs. post-treatment), and aggregated controlled effect sizes of g=0.72 (post-treatment, comparison to waitlist control conditions) and g=0.50 (post-treatment, comparison with TAU/placebo control conditions), respectively. Effect sizes remained stable at follow-up. As the heterogeneity between studies was large, we examined the influence of two a priori specified moderator variables on treatment efficacy. Results showed that trauma-focused treatments were more efficacious than non-trauma-focused interventions, and that treatments including individual sessions yielded larger effect sizes than pure group treatments. As a whole, the findings are in line with earlier meta-analyses showing that the best effects can be achieved with individual trauma-focused treatments.

  16. Bottleneck analysis and strategic planning using Tanahashi model for childhood diarrhea management in Gujarat, Western India.

    Science.gov (United States)

    Rupani, Mihir Prafulbhai; Gaonkar, Narayan T; Bhatt, Gneyaa S

    2016-10-01

    In spite of continued efforts, India is still lagging behind in achieving its MDG goals. The objectives of this study were to identify stake-holders who have a role to play in childhood diarrhea management, to identify gaps in childhood diarrhea management and to propose strategic options for relieving these gaps. Bottleneck analysis exercise was carried out based on the Tanahashi model in six High Priority Districts (HPDs) of Gujarat in period between July-November 2013. The major bottlenecks identified for Childhood Diarrhea management were poor demand generation, unsafe drinking water, poor access to improved sanitation facility and lack of equitable distribution and replenishment mechanisms for Oral Rehydration Solution (ORS) packets and Zinc tablets till the front-line worker level. The main strategic options that were suggested for relieving these bottlenecks were Zinc-ORS roll out in scale-up districts, develop Information Education Communication/Behaviour Change Communication (IEC/BCC) plan for childhood diarrhea management at state/district level, use of Drug Logistics Information Management System (DLIMS) software for supply chain management of Zinc-ORS, strengthening of chlorination activity at household level, monitoring implementation of Nirmal Bharat Abhiyaan (NBA) for constructing improved sanitation facilities at household level and to develop an IEC/BCC plan for hygiene promotion and usage of sanitary latrines. Use of Zinc tablets need to be intensified through an effective scale-up. Adequate demand generation activity is needed. There is need to address safe drinking water and improved sanitation measures at household levels. Multi-sectoral engagements and ownership of Zinc-ORS program is the need of the hour.

  17. Individual and community-level socioeconomic position and its association with adolescents experience of childhood sexual abuse: a multilevel analysis of six countries in Sub-Saharan Africa

    Directory of Open Access Journals (Sweden)

    Ismail Yahaya

    2014-01-01

    Full Text Available Abstract: Background: Childhood sexual abuse (CSA is a substantial global health and human rights problem and consequently a growing concern in sub-Saharan Africa. We examined the association between individual and community-level socioeconomic status (SES and the likelihood of reporting CSA. Methods: We applied multiple multilevel logistic regression analysis on Demographic and Health Survey data for 6,351female adolescents between the ages of 15 and 18 years from six countries in sub-Saharan Africa, between 2006 and 2008. Results: About 70% of the reported cases of CSA were between 14 and 17 years. Zambia had the highest proportion of reported cases of CSA (5.8%. At the individual and community level, we found that there was no association between CSA and socioeconomic position. This study provides evidence that the likelihood of reporting CSA cut across all individual SES as well as all community socioeconomic strata. Conclusions: We found no evidence of socioeconomic differentials in adolescents’ experience of CSA, suggesting that adolescents from the six countries studied experienced CSA regardless of their individual- and community-level socioeconomic position. However, we found some evidence of geographical clustering, adolescents in the same community are subject to common contextual influences. Further studies are needed to explore possible effects of countries’ political, social, economic, legal, and cultural impact on childhood sexual abuse.

  18. Effects of geographic scale on population factors in acute disease diffusion analysis

    Institute of Scientific and Technical Information of China (English)

    Poh-Chin Lai; Chun Bong Chow; Ho Ting Wong; Kim Hung Kwong; Shao Haei Liu; Wah Kun Tong; Wai Keung Cheung; Wing Leung Wong; Yat Wah Kwan

    2015-01-01

    Objective:To explore socio-demographic data of the population as proxies for risk factors in disease transmission modeling at different geographic scales. Methods: Patient records of confirmed H1N1 influenza were analyzed at three geographic aggregation levels together with population census statistics. Results:The study confirmed that four population factors were related in different degrees to disease incidence, but the results varied according to spatial resolution. The degree of association actually decreased when data of a higher spatial resolution were used. Conclusions:We concluded that variables at suitable spatial resolution may be useful in improving the predictive powers of models for disease outbreaks.

  19. Geographic classification of spanish and Australian tempranillo red wines by visible and near-infrared spectroscopy combined with multivariate analysis.

    Science.gov (United States)

    Liu, L; Cozzolino, D; Cynkar, W U; Gishen, M; Colby, C B

    2006-09-01

    Visible (vis) and near-infrared (NIR) spectroscopy combined with multivariate analysis was used to classify the geographical origin of commercial Tempranillo wines from Australia and Spain. Wines (n = 63) were scanned in the vis and NIR regions (400-2500 nm) in a monochromator instrument in transmission. Principal component analysis (PCA), discriminant partial least-squares discriminant analysis (PLS-DA) and linear discriminant analysis (LDA) based on PCA scores were used to classify Tempranillo wines according to their geographical origin. Full cross-validation (leave-one-out) was used as validation method when PCA and LDA classification models were developed. PLS-DA models correctly classified 100% and 84.7% of the Australian and Spanish Tempranillo wine samples, respectively. LDA calibration models correctly classified 72% of the Australian wines and 85% of the Spanish wines. These results demonstrate the potential use of vis and NIR spectroscopy, combined with chemometrics as a rapid method to classify Tempranillo wines accordingly to their geographical origin.

  20. The role of poverty rate and racial distribution in the geographic clustering of breast cancer survival among older women: a geographic and multilevel analysis.

    Science.gov (United States)

    Schootman, Mario; Jeffe, Donna B; Lian, Min; Gillanders, William E; Aft, Rebecca

    2009-03-01

    The authors examined disparities in survival among women aged 66 years or older in association with census-tract-level poverty rate, racial distribution, and individual-level factors, including patient-, treatment-, and tumor-related factors, utilization of medical care, and mammography use. They used linked data from the 1992-1999 Surveillance, Epidemiology, and End Results (SEER) programs, 1991-1999 Medicare claims, and the 1990 US Census. A geographic information system and advanced statistics identified areas of increased or reduced breast cancer survival and possible reasons for geographic variation in survival in 2 of the 5 SEER areas studied. In the Detroit, Michigan, area, one geographic cluster of shorter-than-expected breast cancer survival was identified (hazard ratio (HR) = 1.60). An additional area where survival was longer than expected approached statistical significance (HR = 0.4; P = 0.056). In the Atlanta, Georgia, area, one cluster of shorter- (HR = 1.81) and one cluster of longer-than-expected (HR = 0.72) breast cancer survival were identified. Stage at diagnosis and census-tract poverty (and patient's race in Atlanta) explained the geographic variation in breast cancer survival. No geographic clusters were identified in the 3 other SEER programs. Interventions to reduce late-stage breast cancer, focusing on areas of high poverty and targeting African Americans, may reduce disparities in breast cancer survival in the Detroit and Atlanta areas.

  1. URBAN CHILDHOOD ROUTINES MEDIATED BY TECHNOLOGY: A VISUAL ANALYSIS

    Directory of Open Access Journals (Sweden)

    González-Patiño, Javier

    2011-07-01

    Full Text Available With the goal of documenting routines in which a technological component had some type of impact and observe the influences of immediate environments, exploring meaning and sense, interviews and some observations and, especially, a series of photographs taken by a young girl about her daily life were collected. The purpose of this article is to foster a critical debate about the social and developmental consequences that have been attributed to changes in the living conditions of contemporary Western urban children. For the analytical approach and the analysis of the data, it was especially important to take into consideration the characteristics of the case study participant, a high social class 12 year old pre-adolescent who lives in a home where a large variety of information and communication technology equipment is at her disposal. The conclusions that are presented mainly revolve around two issues. First, related to the emergence of multimodal communication situations, of increasingly semiotic complexity, promoted by digital practices visible in different styles of mediation in the uses of technologies identified as: "convergence", "divergence" and "accessibility". Second, that these technological practices facilitate transformations in space, whether public, private or virtual, altering the importance that traditionally held by other places in the processes of socialization of urban children. This article is published in Spanish.

  2. What Influences Geography Teachers' Usage of Geographic Information Systems? A Structural Equation Analysis

    Science.gov (United States)

    Lay, Jinn-Guey; Chi, Yu-Lin; Hsieh, Yeu-Sheng; Chen, Yu-Wen

    2013-01-01

    Understanding the usage of the geographic information system (GIS) among geography teachers is a crucial step in evaluating the current dissemination of GIS knowledge and skills in Taiwan's educational system. The primary contribution of this research is to further our understanding of the factors that affect teachers' GIS usage. The structural…

  3. Distribution of Health-Related Physical Fitness in Texas Youth: A Demographic and Geographic Analysis

    Science.gov (United States)

    Welk, Gregory J.; Meredith, Marilu D.; Ihmels, Michelle; Seeger, Chris

    2010-01-01

    This study examined demographic and geographic variability in aggregated school-level data on the percentage of students achieving the FITNESSGRAM[R] Healthy Fitness Zones[TM] (HFZ). Three-way analyses of variance were used to examine differences in fitness achievement rates among schools that had distinct diversity and socioeconomic status…

  4. Authentication of geographical origin of palm oil by chromatographic fingerprinting of triacylglycerols and partial least square-discriminant analysis.

    Science.gov (United States)

    Ruiz-Samblás, Cristina; Arrebola-Pascual, Cristina; Tres, Alba; van Ruth, Saskia; Cuadros-Rodríguez, Luis

    2013-11-15

    Main goals of the present work were to develop authentication models based on liquid and gas chromatographic fingerprinting of triacylglycerols (TAGs) from palm oil of different geographical origins in order to compare them. For this purpose, a set of palm oil samples were collected from different continents: South eastern Asia, Africa and South America. For the analysis of the information in these fingerprint profiles, a pattern recognition technique such as partial least square discriminant analysis (PLS-DA) was applied to discriminate the geographical origin of these oils, at continent level. The liquid chromatography, coupled to a charged aerosol detector, (HPLC-CAD) TAGs separation was optimized in terms of mobile phase composition and by means of a solid silica core column. The gas chromatographic method with a mass spectrometer was applied under high temperature (HTGC-MS) in order to analyze the intact TAGs. Satisfactory chromatographic resolution within a short total analysis time was achieved with both chromatographic approaches and without any prior sample treatment. The rates of successful in prediction of the geographical origin of the 85 samples varied between 70% and 100%.

  5. Geographic Tongue

    Science.gov (United States)

    ... cases, most often related to eating hot, spicy, salty or acidic foods Many people with geographic tongue ... sensitive oral tissues, including: Hot, spicy, acidic or salty foods Tobacco products Toothpaste that contains tartar-control ...

  6. Geographic information system for fusion and analysis of high-resolution remote sensing and ground data

    Science.gov (United States)

    Freeman, Anthony; Way, Jo Bea; Dubois, Pascale; Leberl, Franz

    1993-01-01

    We seek to combine high-resolution remotely sensed data with models and ground truth measurements, in the context of a Geographical Information System (GIS), integrated with specialized image processing software. We will use this integrated system to analyze the data from two Case Studies, one at a boreal forest site, the other a tropical forest site. We will assess the information content of the different components of the data, determine the optimum data combinations to study biogeophysical changes in the forest, assess the best way to visualize the results, and validate the models for the forest response to different radar wavelengths/polarizations. During the 1990's, unprecedented amounts of high-resolution images from space of the Earth's surface will become available to the applications scientist from the LANDSAT/TM series, European and Japanese ERS-1 satellites, RADARSAT and SIR-C missions. When the Earth Observation Systems (EOS) program is operational, the amount of data available for a particular site can only increase. The interdisciplinary scientist, seeking to use data from various sensors to study his site of interest, may be faced with massive difficulties in manipulating such large data sets, assessing their information content, determining the optimum combinations of data to study a particular parameter, visualizing his results and validating his model of the surface. The techniques to deal with these problems are also needed to support the analysis of data from NASA's current program of Multi-sensor Airborne Campaigns, which will also generate large volumes of data. In the Case Studies outlined in this proposal, we will have somewhat unique data sets. For the Bonanza Creek Experimental Forest (Case 1) calibrated DC-8 SAR (Synthetic Aperture Radar) data and extensive ground truth measurement are already at our disposal. The data set shows documented evidence to temporal change. The Belize Forest Experiment (Case 2) will produce calibrated DC-8 SAR

  7. Do race, neglect, and childhood poverty predict physical health in adulthood? A multilevel prospective analysis.

    Science.gov (United States)

    Nikulina, Valentina; Widom, Cathy Spatz

    2014-03-01

    Childhood neglect and poverty often co-occur and both have been linked to poor physical health outcomes. In addition, Blacks have higher rates of childhood poverty and tend to have worse health than Whites. This paper examines the unique and interacting effects of childhood neglect, race, and family and neighborhood poverty on adult physical health outcomes. This prospective cohort design study uses a sample (N=675) of court-substantiated cases of childhood neglect and matched controls followed into adulthood (M(age)=41). Health indicators (C-Reactive Protein [CRP], hypertension, and pulmonary functioning) were assessed through blood collection and measurements by a registered nurse. Data were analyzed using hierarchical linear models to control for clustering of participants in childhood neighborhoods. Main effects showed that growing up Black predicted CRP and hypertension elevations, despite controlling for neglect and childhood family and neighborhood poverty and their interactions. Multivariate results showed that race and childhood adversities interacted to predict adult health outcomes. Childhood family poverty predicted increased risk for hypertension for Blacks, not Whites. In contrast, among Whites, childhood neglect predicted elevated CRP. Childhood neighborhood poverty interacted with childhood family poverty to predict pulmonary functioning in adulthood. Gender differences in health indicators were also observed. The effects of childhood neglect, childhood poverty, and growing up Black in the United States are manifest in physical health outcomes assessed 30 years later. Implications are discussed.

  8. Analysis of 14C and 13C in teeth provides precise birth dating and clues to geographical origin

    Science.gov (United States)

    K, Alkass; BA, Buchholz; H, Druid; KL, Spalding

    2011-01-01

    The identification of human bodies in situations when there are no clues as to the person’s identity from circumstantial data, poses a difficult problem to investigators. The determination of age and sex of the body can be crucial in order to limit the search to individuals that are a possible match. We analyzed the proportion of bomb pulse derived carbon-14 (14C) incorporated in the enamel of teeth from individuals from different geographical locations. The ‘bomb pulse’ refers to a significant increase in 14C levels in the atmosphere caused by above ground test detonations of nuclear weapons during the cold war (1955-1963). By comparing 14C levels in enamel with 14C atmospheric levels systematically recorded over time, high precision birth dating of modern biological material is possible. Above ground nuclear bomb testing was largely restricted to a couple of locations in the northern hemisphere, producing differences in atmospheric 14C levels at various geographical regions, particularly in the early phase. Therefore, we examined the precision of 14C birth dating of enamel as a function of time of formation and geographical location. We also investigated the use of the stable isotope 13C as an indicator of geographical origin of an individual. Dental enamel was isolated from 95 teeth extracted from 84 individuals to study the precision of the 14C method along the bomb spike. For teeth formed before 1955 (N = 17), all but one tooth showed negative Δ14C values. Analysis of enamel from teeth formed during the rising part of the bomb-spike (1955-1963, N = 12) and after the peak (>1963, N = 66) resulted in an average absolute date of birth estimation error of 1.9 ±1.4 and 1.3 ± 1.0 years, respectively. Geographical location of an individual had no adverse effect on the precision of year of birth estimation using radiocarbon dating. In 46 teeth, measurement of 13C was also performed. Scandinavian teeth showed a substantially greater depression in average δ13C

  9. Geospatial mapping of Antarctic coastal oasis using geographic object-based image analysis and high resolution satellite imagery

    Science.gov (United States)

    Jawak, Shridhar D.; Luis, Alvarinho J.

    2016-04-01

    An accurate spatial mapping and characterization of land cover features in cryospheric regions is an essential procedure for many geoscientific studies. A novel semi-automated method was devised by coupling spectral index ratios (SIRs) and geographic object-based image analysis (OBIA) to extract cryospheric geospatial information from very high resolution WorldView 2 (WV-2) satellite imagery. The present study addresses development of multiple rule sets for OBIA-based classification of WV-2 imagery to accurately extract land cover features in the Larsemann Hills, east Antarctica. Multilevel segmentation process was applied to WV-2 image to generate different sizes of geographic image objects corresponding to various land cover features with respect to scale parameter. Several SIRs were applied to geographic objects at different segmentation levels to classify land mass, man-made features, snow/ice, and water bodies. We focus on water body class to identify water areas at the image level, considering their uneven appearance on landmass and ice. The results illustrated that synergetic usage of SIRs and OBIA can provide accurate means to identify land cover classes with an overall classification accuracy of ≍97%. In conclusion, our results suggest that OBIA is a powerful tool for carrying out automatic and semiautomatic analysis for most cryospheric remote-sensing applications, and the synergetic coupling with pixel-based SIRs is found to be a superior method for mining geospatial information.

  10. Geographic Object-based Image Analysis for Developing Cryospheric Surface Mapping Application using Remotely Sensed High-Resolution Satellite Imagery

    Science.gov (United States)

    Jawak, S. D.; Luis, A. J.

    2015-12-01

    A novel semi-automated method was devised by coupling spectral index ratios (SIRs) and geographic object-based image analysis (GEOBIA) to extract cryospheric geoinformation from very high resolution WorldView 2 (WV-2) satellite imagery. The present study addresses development of multiple rule sets for GEOBIA-based classification of WV-2 imagery to accurately extract land cover features in the Larsemann Hills, Antarctica. Multi-level segmentation process was applied to WV-2 image to generate different sizes of geographic image objects corresponding to various land cover features w.r.t scale parameter. Several SIRs were applied to geographic objects at different segmentation levels to classify landmass, man-made features, snow/ice, and water bodies. A specific attention was paid to water body class to identify water areas at the image level, considering their uneven appearance on landmass and ice. The results illustrated that synergetic usage of SIRs and GEOBIA can provide accurate means to identify land cover classes with an overall classification accuracy of ≈97%. In conclusion, the results suggest that GEOBIA is a powerful tool for carrying out automatic and semiautomatic analysis for most cryospheric remote-sensing applications, and the synergetic coupling with pixel-based SIRs is found to be a superior method for mining geoinformation.

  11. Geographical analysis of parking land use in Genaveh applying AHP Model

    Directory of Open Access Journals (Sweden)

    Gh. Hosseini Lagha

    2012-01-01

    Full Text Available Extended Abstract 1- IntroductionEach year Genaveh Port receives millions of tourists (2302154 people in Nowruz Holidays in 1390 from all over the country for its tourist attractions and trade and recreation centers. The presence of this huge populace has created several traffic problems, the main root of which can be found in the shortage or the incorrect positioning of the function of parking lots in this city. However, the issue gets into its peak in the time there is boom in tourism in holiday seasons. field data, a questionnaire with a sample size of 320 participants including 100 citizens and 220 tourists has been incorporated, This applied study uses a descriptive analytical research design.In the analysis of the current situation, and for providing the and SPSS has been used for further analysis. After assessing the area and the number of required parking lots applying parking building methods, the influential standards in situating public parking lots has been weighted through the analytic hierarchy process (AHP in Arc GIS software zone, and then appropriate places for launching parking lots has been recognized by OWA (Ordered Weighted Average fuzzy method. Results show that with regard to the need for 1863 parking lots in addition to the current lots in the studied area in one day, there exists no logical relations between the demanded parking lots and the existing parking lots in the city of Genaveh. Nevertheless, it should be admitted that the present parking lots in the city are appropriate considering the geographical standards; but limitations exist with regard to the number of these lots. Hence, considering the characteristics of this city, the most logical option is the use of smart parking. 2- Theoretical Bases- Traffic Traffic is an international term; it means transportation vehicles and passersby walk on roads and adding three humans, vehicle and road are formed (Rezaei, 1369, p. 7.- Stop surface carThe average surface to

  12. Robust Principal Component Analysis and Geographically Weighted Regression: Urbanization in the Twin Cities Metropolitan Area of Minnesota.

    Science.gov (United States)

    Ghosh, Debarchana; Manson, Steven M

    2008-01-01

    In this paper, we present a hybrid approach, robust principal component geographically weighted regression (RPCGWR), in examining urbanization as a function of both extant urban land use and the effect of social and environmental factors in the Twin Cities Metropolitan Area (TCMA) of Minnesota. We used remotely sensed data to treat urbanization via the proxy of impervious surface. We then integrated two different methods, robust principal component analysis (RPCA) and geographically weighted regression (GWR) to create an innovative approach to model urbanization. The RPCGWR results show significant spatial heterogeneity in the relationships between proportion of impervious surface and the explanatory factors in the TCMA. We link this heterogeneity to the "sprawling" nature of urban land use that has moved outward from the core Twin Cities through to their suburbs and exurbs.

  13. Analysis of Greedy Decision Making for Geographic Routing for Networks of Randomly Moving Objects

    Directory of Open Access Journals (Sweden)

    Amber Israr

    2016-04-01

    Full Text Available Autonomous and self-organizing wireless ad-hoc communication networks for moving objects consist of nodes, which use no centralized network infrastructure. Examples of moving object networks are networks of flying objects, networks of vehicles, networks of moving people or robots. Moving object networks have to face many critical challenges in terms of routing because of dynamic topological changes and asymmetric networks links. A suitable and effective routing mechanism helps to extend the deployment of moving nodes. In this paper an attempt has been made to analyze the performance of the Greedy Decision method (position aware distance based algorithm for geographic routing for network nodes moving according to the random waypoint mobility model. The widely used GPSR (Greedy Packet Stateless Routing protocol utilizes geographic distance and position based data of nodes to transmit packets towards destination nodes. In this paper different scenarios have been tested to develop a concrete set of recommendations for optimum deployment of distance based Greedy Decision of Geographic Routing in randomly moving objects network

  14. Geographical and biological analysis of the water quality of Moravica spring in the Sokobanjska Moravica drainage basin, Serbia

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    Stanković S.

    2012-01-01

    Full Text Available In this work we performed a geographical analysis of the Moravica spring locality in the Sokobanjska Moravica drainage basin in Serbia, as well as an analysis of the physical, chemical, and biological parameters of the water during a one-year period. The basic sanitary characteristics and physical, chemical, and biological parameters, necessary for understanding locality conditions, were studied, and the saprobity index, class of quality, O/H index, degree of saprobity, degree of trophicity, and category based on the phosphatase activity index (PAI were determined. Our results point to the need for continual monitoring of the water quality in the spring locality.

  15. Do race, neglect, and childhood poverty predict physical health in adulthood? A multilevel prospective analysis

    OpenAIRE

    Nikulina, Valentina

    2013-01-01

    Childhood neglect and poverty often co-occur and both have been linked to poor physical health outcomes. In addition, Blacks have higher rates of childhood poverty and tend to have worse health than Whites. This paper examines the unique and interacting effects of childhood neglect, race, and family and neighborhood poverty on adult physical health outcomes. This prospective cohort design study uses a sample (N = 675) of court-substantiated cases of childhood neglect and matched controls foll...

  16. Socio-geographic analysis of wild land fires: causes of the 2006's wildfires in Galicia (Spain)

    Energy Technology Data Exchange (ETDEWEB)

    Balsa-Barreiro, J.; Hermosilla, T.

    2013-07-01

    Aim of study: To propose a methodology to establish motivations underlying wildland fire episodes by analyzing both the socioeconomics of the affected territory and the geographical distribution of the wildfire. Area of study: The wildfires occurred during 2006 in Galicia, in the NW of Spain, were analyzed and compared regard to the previous years. Material and methods: The proposed methodology in this study is divided into four steps: (a) definition of the forest context, (b) fire episode and socioeconomic data collection, (c) geospatial representation through map production, and (d) joint analysis and data interpretation. A combined analysis of the spatial and temporal coincidence of wildfire and the socioeconomic activities is performed. Main results: A combined analysis of the spatial and temporal coincidence of wildfire dynamics and the socioeconomic activities allow us to assess and to interpret wildfire causes and motivations of socioeconomic groups. In our area study, a broad analysis indicates that wildfire recurrence within this region is related to an accelerated rural flight process which exacerbates the conflict between rural and urban models. Research highlights: The socio-geographical analysis of a territory's wildfire dynamics enables us to establish possible causes and motivations of their origins. Providing the specific contextual and socioeconomic information, this methodology has potential applicability across varied study locations. (Author)

  17. Geographic Information System and tools of spatial analysis in a pneumococcal vaccine trial

    Directory of Open Access Journals (Sweden)

    Tanskanen Antti

    2012-01-01

    Full Text Available Abstract Background The goal of this Geographic Information System (GIS study was to obtain accurate information on the locations of study subjects, road network and services for research purposes so that the clinical outcomes of interest (e.g., vaccine efficacy, burden of disease, nasopharyngeal colonization and its reduction could be linked and analyzed at a distance from health centers, hospitals, doctors and other important services. The information on locations can be used to investigate more accurate crowdedness, herd immunity and/or transmission patterns. Method A randomized, placebo-controlled, double-blind trial of an 11-valent pneumococcal conjugate vaccine (11PCV was conducted in Bohol Province in central Philippines, from July 2000 to December 2004. We collected the information on the geographic location of the households (N = 13,208 of study subjects. We also collected a total of 1982 locations of health and other services in the six municipalities and a comprehensive GIS data over the road network in the area. Results We calculated the numbers of other study subjects (vaccine and placebo recipients, respectively within the neighborhood of each study subject. We calculated distances to different services and identified the subjects sharing the same services (calculated by distance. This article shows how to collect a complete GIS data set for human to human transmitted vaccine study in developing country settings in an efficient and economical way. Conclusions The collection of geographic locations in intervention trials should become a routine task. The results of public health research may highly depend on spatial relationships among the study subjects and between the study subjects and the environment, both natural and infrastructural. Trial registration number ISRCTN: ISRCTN62323832

  18. Geographic distribution of Staphylococcus aureus causing invasive infections in Europe: a molecular-epidemiological analysis.

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    Hajo Grundmann

    2010-01-01

    Full Text Available BACKGROUND: Staphylococcus aureus is one of the most important human pathogens and methicillin-resistant variants (MRSAs are a major cause of hospital and community-acquired infection. We aimed to map the geographic distribution of the dominant clones that cause invasive infections in Europe. METHODS AND FINDINGS: In each country, staphylococcal reference laboratories secured the participation of a sufficient number of hospital laboratories to achieve national geo-demographic representation. Participating laboratories collected successive methicillin-susceptible (MSSA and MRSA isolates from patients with invasive S. aureus infection using an agreed protocol. All isolates were sent to the respective national reference laboratories and characterised by quality-controlled sequence typing of the variable region of the staphylococcal spa gene (spa typing, and data were uploaded to a central database. Relevant genetic and phenotypic information was assembled for interactive interrogation by a purpose-built Web-based mapping application. Between September 2006 and February 2007, 357 laboratories serving 450 hospitals in 26 countries collected 2,890 MSSA and MRSA isolates from patients with invasive S. aureus infection. A wide geographical distribution of spa types was found with some prevalent in all European countries. MSSA were more diverse than MRSA. Genetic diversity of MRSA differed considerably between countries with dominant MRSA spa types forming distinctive geographical clusters. We provide evidence that a network approach consisting of decentralised typing and visualisation of aggregated data using an interactive mapping tool can provide important information on the dynamics of MRSA populations such as early signalling of emerging strains, cross border spread, and importation by travel. CONCLUSIONS: In contrast to MSSA, MRSA spa types have a predominantly regional distribution in Europe. This finding is indicative of the selection and spread

  19. Analysis on Objects of Geographic National Conditions Monitoring%地理国情监测对象分析

    Institute of Scientific and Technical Information of China (English)

    张成

    2014-01-01

    The geographic national conditions monitoring is an important mission of the spatial information science in the new era ,and also an important part of the Twelfth Five-year-plan of the national surveying and mapping geographical Informa-tion development .In this paper,the classification of the objects of geographic national conditions monitoring and some classifi-cation systems of geographic information are discussed ,and detailed discussion and analysis on monitoring objects are giving from the view of classification of monitoring application .Nowadays ,the attention to monitoring objects are focused on the natu-ral and humanistic geography elements ,but the anthrop and economic factors has been neglected more or less .%地理国情监测是新时期空间信息科学的重要使命,也是国家测绘地理信息发展“十二五”规划的重要内容之一。文章综合分析了地理国情监测对象的分类方法和目前地理信息的一些分类体系,并从监测应用领域分类对监测对象进行详细探讨和分析。目前地理国情监测对象注意力集中在对自然地理要素和人文地理要素,对人文经济要素的监测则显不足。

  20. 106例儿童孤独症的临床特征分析%Clinical Analysis for 106 Cases of Childhood Autism

    Institute of Scientific and Technical Information of China (English)

    张新波; 柯晓燕; 罗硕军; 林节

    2002-01-01

    Objective To investigate the clinical features of childhood autism. Methods Clinical analysis for 106 casesof clildhood autism by Childhood Autism Rating Scale (CARS) .Results Onset age on0~ 11 month's autism are severe than11 ~ 23 month and 24 ~ 36 month, especially on human relatedness, use of body, relation to objects, visual responsiveness,auditory responsiveness, verbal sommunication and global impression. Cocnclusion The chnical features of childhood autismrelate to onset age.

  1. Supervised feature evaluation by consistency analysis: application to measure sets used to characterise geographic objects

    CERN Document Server

    Taillandier, Patrick

    2012-01-01

    Nowadays, supervised learning is commonly used in many domains. Indeed, many works propose to learn new knowledge from examples that translate the expected behaviour of the considered system. A key issue of supervised learning concerns the description language used to represent the examples. In this paper, we propose a method to evaluate the feature set used to describe them. Our method is based on the computation of the consistency of the example base. We carried out a case study in the domain of geomatic in order to evaluate the sets of measures used to characterise geographic objects. The case study shows that our method allows to give relevant evaluations of measure sets.

  2. Childhood Trauma Questionnaire (CTQ) in Brazilian Samples of Different Age Groups: Findings from Confirmatory Factor Analysis

    Science.gov (United States)

    Grassi-Oliveira, Rodrigo; Cogo-Moreira, Hugo; Salum, Giovanni Abrahão; Brietzke, Elisa; Viola, Thiago Wendt; Manfro, Gisele Gus; Kristensen, Christian Haag; Arteche, Adriane Xavier

    2014-01-01

    The Childhood Trauma Questionnaire (CTQ) is internationally accepted as a key tool for the assessment of childhood abuse and neglect experiences. However, there are relative few psychometric studies available and some authors have proposed two different factor solutions. We examined the dimensional structure and internal consistency of the Brazilian version of the CTQ. A total of 1,925 participants from eight different clinical and non-clinical samples including adolescents, adults and elders were considered in this study. First, we performed Confirmatory Factor Analysis to investigate the goodness of fit of the two proposed competitive factor structure models for the CTQ. We also investigated the internal consistency of all factors. Second, multi-group analyses were used to investigate measurement invariance and population heterogeneity across age groups and sex. Our findings revealed that the alternative factor structure as opposed to the original factor structure was the most appropriate model within adolescents and adults Brazilian samples. We provide further evidence for the validity and reliability of the CTQ within the Brazilian samples and report that the alternative model showed an improvement in fit indexes and may be a better alternative over the original model. PMID:24475237

  3. Global characteristics of childhood acute promyelocytic leukemia.

    Science.gov (United States)

    Zhang, L; Samad, A; Pombo-de-Oliveira, M S; Scelo, G; Smith, M T; Feusner, J; Wiemels, J L; Metayer, C

    2015-03-01

    Acute promyelocytic leukemia (APL) comprises approximately 5-10% of childhood acute myeloid leukemia (AML) cases in the US. While variation in this percentage among other populations was noted previously, global patterns of childhood APL have not been thoroughly characterized. In this comprehensive review of childhood APL, we examined its geographic pattern and the potential contribution of environmental factors to observed variation. In 142 studies (spanning >60 countries) identified, variation was apparent-de novo APL represented from 2% (Switzerland) to >50% (Nicaragua) of childhood AML in different geographic regions. Because a limited number of previous studies addressed specific environmental exposures that potentially underlie childhood APL development, we gathered 28 childhood cases of therapy-related APL, which exemplified associations between prior exposures to chemotherapeutic drugs/radiation and APL diagnosis. Future population-based studies examining childhood APL patterns and the potential association with specific environmental exposures and other risk factors are needed.

  4. Decomposed pairwise regression analysis of genetic and geographic distances reveals a metapopulation structure of stream-dwelling Dolly Varden charr.

    Science.gov (United States)

    Koizumi, Itsuro; Yamamoto, Shoichiro; Maekawa, Koji

    2006-10-01

    Isolation by distance is usually tested by the correlation of genetic and geographic distances separating all pairwise populations' combinations. However, this method can be significantly biased by only a few highly diverged populations and lose the information of individual population. To detect outlier populations and investigate the relative strengths of gene flow and genetic drift for each population, we propose a decomposed pairwise regression analysis. This analysis was applied to the well-described one-dimensional stepping-stone system of stream-dwelling Dolly Varden charr (Salvelinus malma). When genetic and geographic distances were plotted for all pairs of 17 tributary populations, the correlation was significant but weak (r(2) = 0.184). Seven outlier populations were determined based on the systematic bias of the regression residuals, followed by Akaike's information criteria. The best model, 10 populations included, showed a strong pattern of isolation by distance (r(2) = 0.758), suggesting equilibrium between gene flow and genetic drift in these populations. Each outlier population was also analysed by plotting pairwise genetic and geographic distances against the 10 nonoutlier populations, and categorized into one of the three patterns: strong genetic drift, genetic drift with a limited gene flow and a high level of gene flow. These classifications were generally consistent with a priori predictions for each population (physical barrier, population size, anthropogenic impacts). Combined the genetic analysis with field observations, Dolly Varden in this river appeared to form a mainland-island or source-sink metapopulation structure. The generality of the method will merit many types of spatial genetic analyses.

  5. Understanding heterogeneity in grey matter research of adults with childhood maltreatment-A meta-analysis and review.

    Science.gov (United States)

    Paquola, Casey; Bennett, Maxwell R; Lagopoulos, Jim

    2016-10-01

    Childhood trauma has been associated with long term effects on prefrontal-limbic grey matter. A literature search was conducted to identify structural magnetic resonance imaging studies of adults with a history of childhood trauma. We performed three meta-analyses. Hedges' g effect sizes were calculated for each study providing hippocampal or amygdala volumes of trauma and non-trauma groups. Seed based differential mapping was utilised to synthesise whole brain voxel based morphometry (VBM) studies. A total of 38 articles (17 hippocampus, 13 amygdala, 19 whole brain VBM) were included in the meta-analyses. Trauma cohorts exhibited smaller hippocampus and amygdala volumes bilaterally. The most robust findings of the whole brain VBM meta-analysis were reduced grey matter in the right dorsolateral prefrontal cortex and right hippocampus amongst adults with a history of childhood trauma. Subgroup analyses and meta-regressions showed results were moderated by age, gender, the cohort's psychiatric health and the study's definition of childhood trauma. We provide evidence of abnormal grey matter in prefrontal-limbic brain regions of adults with a history of childhood maltreatment.

  6. Impacts of measurement protocols on blood pressure tracking from childhood into adulthood: a metaregression analysis.

    Science.gov (United States)

    Chen, Xiaoli; Wang, Youfa; Appel, Lawrence J; Mi, Jie

    2008-03-01

    The best approach for blood pressure (BP) measurement in children remains controversial, specifically regarding the choice of Korotkoff phase 4 versus Korotkoff phase 5 for diastolic BP (DBP) and the use of automated devices. To examine the impacts of different BP measurement protocols on BP tracking from childhood into adulthood, we conducted a meta-analysis of 50 related studies published between 1970 and 2006 identified based on a systematic search of PubMed. These studies provided 617 data points (tracking correlation coefficient, our outcome variable) for systolic BP and 547 data points for DBP for our meta-analysis. The explanatory variables included the use of Korotkoff phase 4/Korotkoff phase 5, BP device, and number of BP measurements per visit. Analyses were adjusted for potential confounders, including sex, baseline age, follow-up length, publication year, and study country. Tracking correlation coefficients for DBP measured using Korotkoff phase 4 was higher than that of Korotkoff phase 5 by 0.035 but not significant. DBP tracking assessed by automated device was higher than that of Korotkoff phase 5 by 0.152 (P=0.024) and higher than the mercury manometer by 0.223 (P=0.005). BP tracking was slightly higher with multiple BP measurements per visit, but measurements of >or=3 times did not improve the tracking further compared with 2 measurements. Although policy-making bodies currently recommend the use of Korotkoff phase 5 to assess DBP in children, our metaregression analysis did not support the recommendation. In general, Korotkoff phase 4 seems to be different from Korotkoff phase 5, and automated device is a promising approach for BP assessment in childhood.

  7. Analysis of Seminar 82 - World Congress on Future Special Education "The Role of the Family in Early Childhood Education".

    Science.gov (United States)

    Updike, Juliette; Foley, Gilbert M.

    The paper is an analysis of seminar 82 of the World Congress on Future Special Education, "The Role of the Family in Early Childhood Education". Issues and problems, alternative solutions and strategies, and pros and cons are listed for each of the following four presentations: "An Assessment Scale - Family Attachment to the High Risk Infant" (G.…

  8. Are School Nurses an Overlooked Resource in Reducing Childhood Obesity? A Systematic Review and Meta-analysis

    Science.gov (United States)

    Schroeder, Krista; Travers, Jasmine; Smaldone, Arlene

    2016-01-01

    Background: Schools are a key setting for childhood obesity interventions, yet nurses are not often included in delivering these interventions. The objective of this systematic review and meta-analysis was to examine school-based interventions involving nurses in a role beyond anthropometric measurement for effect on change in body measures.…

  9. Analysis of the academic production on evaluation in/of Early Childhood Education in the period 2000-2012

    Directory of Open Access Journals (Sweden)

    Graciele Glap

    2014-04-01

    Full Text Available This article is originated from a qualitative research, state of the art type, which had an inventory character derived from scientific papers on evaluation in/of Early Childhood Education, collected through electronic consultation and printed productions, published from 2000 to 2012. 47 works were found, of which 24 were articles, 20 were dissertations and 3 were theses. The abstracts of these works were analyzed using the ALCESTE software, and the corpus analysis is structured in two categories: evaluation in Early Childhood Education, directed to researches on evaluation in the micro school context, and evaluation of Early Childhood Education, related to the meso and macro school context, that is to say, the evaluation of policies/programs and institutions.

  10. Nonparametric analysis of the time structure of seismicity in a geographic region

    Directory of Open Access Journals (Sweden)

    A. Quintela-del-Río

    2002-06-01

    Full Text Available As an alternative to traditional parametric approaches, we suggest nonparametric methods for analyzing temporal data on earthquake occurrences. In particular, the kernel method for estimating the hazard function and the intensity function are presented. One novelty of our approaches is that we take into account the possible dependence of the data to estimate the distribution of time intervals between earthquakes, which has not been considered in most statistics studies on seismicity. Kernel estimation of hazard function has been used to study the occurrence process of cluster centers (main shocks. Kernel intensity estimation, on the other hand, has helped to describe the occurrence process of cluster members (aftershocks. Similar studies in two geographic areas of Spain (Granada and Galicia have been carried out to illustrate the estimation methods suggested.

  11. Trend and geographic analysis for traumatic brain injury mortality and cost based on MarketScan database.

    Science.gov (United States)

    Hu, Jiahui; Ugiliweneza, Beatrice; Meyer, Kimberly; Lad, Shivanand P; Boakye, Maxwell

    2013-10-15

    The objective of the current research was to examine the current epidemiology of traumatic brain injury (TBI); to determine the effects of geographic region, co-morbidities, year of injury, injury severity, and demographics on hospital costs, length of stay (LOS), and mortality. All subjects were drawn from the Thomason Reuters MarketScan(®) database. Statistical methods used included descriptive analysis, bivariate analysis, logistic regression, and the Geographic Information System (GIS) software, ArcMap. We studied 76,313 patients with TBI from 2004 to 2009 (52,721 with commercial insurance and 23,592 with Medicare) from the MarketScan database. As age increased, mortality rate and median LOS increased. The median hospital costs for adults were the highest ($13,000 for ages 18-64) compared with children ($8000 for age 0-14) and elderly persons ($9000 for age ≥ 65). The mortality rate for the elderly population has decreased slightly (11.1% in 2004 to 9.9% in 2009 for men, and 7.0% to 6.9% for women); however, their hospital costs have increased significantly ($6899 in 2004 to $11,567 in 2009 for men; $6784 to $9782 for women). Concerning the impact of geography, the western United States (e.g., Washington and California) had lower mortality rates and higher median costs while the southeast United States had the highest mortality and mixed median costs. Both overall mortality and median LOS have remained relatively stable over the years. Hospital cost, however, has increased for the elderly population even after accounting for the inflation. There is significant geographic variation for both mortality and hospital costs.

  12. Geographically diverse Australian isolates of Melissococcus pluton exhibit minimal genotypic diversity by restriction endonuclease analysis.

    Science.gov (United States)

    Djordjevic, S P; Smith, L A; Forbes, W A; Hornitzky, M A

    1999-04-15

    Melissococcus pluton, the causative agent of European foulbrood is an economically significant disease of honey bees (Apis mellifera) across most regions of the world and is prevalent throughout most states of Australia. 49 Isolates of M. pluton recovered from diseased colonies or honey samples in New South Wales, Queensland, South Australia, Tasmania and Victoria were compared using SDS-PAGE, Western immunoblotting and restriction endonuclease analyses. DNA profiles of all 49 geographically diverse isolates showed remarkably similar AluI profiles although four isolates (one each from Queensland, South Australia, New South Wales and Victoria) displayed minor profile variations compared to AluI patterns of all other isolates. DNA from a subset of the 49 Australian and three isolates from the United Kingdom were digested separately with the restriction endonucleases CfoI, RsaI and DraI. Restriction endonuclease fragment patterns generated using these enzymes were also similar although minor variations were noted. SDS-PAGE of whole cell proteins from 13 of the 49 isolates from different states of Australia, including the four isolates which displayed minor profile variations (AluI) produced indistinguishable patterns. Major immunoreactive proteins of approximate molecular masses of 21, 24, 28, 30, 36, 40, 44, 56, 60, 71, 79 and 95 kDa were observed in immunoblots of whole cell lysates of 22 of the 49 isolates and reacted with rabbit hyperimmune antibodies raised against M. pluton whole cells. Neither SDS-PAGE or immunoblotting was capable of distinguishing differences between geographically diverse isolates of M. pluton. Collectively these data confirm that Australian isolates of M. pluton are genetically homogeneous and that this species may be clonal. Plasmid DNA was not detected in whole cell DNA profiles of any isolate resolved using agarose gel electrophoresis.

  13. BOTTLENECK ANALYSIS AND STRATEGIC PLANNING ON CHILDHOOD DIARRHEA MANAGEMENT IN 6 HIGH PRIORITY DISTRICTS OF GUJARAT

    Directory of Open Access Journals (Sweden)

    Rupani Mihir

    2015-01-01

    Full Text Available Introduction:Bottleneck Analysis and Strategic Planning exercise was carried out in 6 High Priority Districts (HPDs, under Call-to-Action for RMNCH+A strategy.Rationale: In spite of continued efforts, India is still lagging behind in its MDG goals.Objectives: To identify gaps in childhood diarrhea management and propose strategic options for the same.Materials and Methods: Bottleneck analysis exercisewas carried out based on the Tanahashi model, desk review and focused group discussions between district officials, front-line workers and UNICEF officials. These bottlenecks were pertaining to the availability, accessibility, utilization of services and quality of services being provided by the health department.Elaborating the Tanahashi model for the 6 HPDs, 94% of the front-line workers (FLWs had stock of Zinc-ORS; 88% FLWs were trained in diarrhea management; 98% villages had at least one FLW trained in diarrhea management; health care seeking for diarrhea cases was 17%; 5.1% diarrhea cases received Zinc-ORS from health worker and 2.4% care takers prepared Zinc-ORS in safe drinking water.Results: The major bottlenecks identified for Childhood Diarrhea management in the 6 High Priority Districts were poor demand generation, unsafe drinking water, poor access to improved sanitation facility and lack of equitable distribution of Zinc-ORS till the front-line worker level. The main strategic options that were suggested for relieving these bottlenecks were Zinc-ORS roll out in scale-up districts, develop IEC/BCC plan for childhood diarrhea management at state/district level, use of Drug Logistics Information Management System (DLIMS software for supply chain management of Zinc-ORS, strengthening of chlorination activity at household level, monitoring implementation of Nirmal Bharat Abhiyaan (NBA for constructing improved sanitation facilities at household level and to develop an IEC/BCC plan for hygiene promotion and usage of sanitary latrines

  14. Strengthening systems for integrated early childhood development services: a cross-national analysis of governance.

    Science.gov (United States)

    Britto, Pia Rebello; Yoshikawa, Hirokazu; van Ravens, Jan; Ponguta, Liliana Angelica; Reyes, Maria; Oh, Soojin; Dimaya, Roland; Nieto, Ana María; Seder, Richard

    2014-01-01

    While there has been substantial growth in early childhood development (ECD) services in low- and middle-income countries (LMICs), there is considerable inequity in their distribution and quality. Evidence-based governance strategies are necessary, but currently they are insufficient for widespread, quality implementation. In particular, there is a limited understanding of the use of systems approaches for the analysis of ECD services as they go to scale. The aim of this paper is to present findings from four countries, using a cross-national case study approach to explore governance mechanisms required to strengthen national systems of ECD services. While different sets of governance strategies and challenges were identified in each country, overarching themes also emerged with implications for systems strengthening. Study results focus on local, mid-level and central governance, with recommendations for effective coordination and the integration of ECD services in LMICs.

  15. Prevalence of Childhood Sexual Abuse among Lesbian, Gay, and Bisexual People: A Meta-Analysis.

    Science.gov (United States)

    Xu, Yin; Zheng, Yong

    2015-01-01

    In order to determine the prevalence of childhood sexual abuse among gay, lesbian, and bisexual individuals, we conducted a meta-analysis that compiled the results of 65 articles across 9 countries. The results revealed no significant difference in the prevalence of child sexual abuse between homosexual and bisexual people for both sexes. The prevalence of child sexual abuse among female sexual minorities was significantly higher than that among male sexual minorities. The lowest prevalence was found in South America, followed by Asia. The definition of child sexual abuse, dimension used to measure sexual orientation, year of data collection, and the mean age of participants at the time of assessment influenced the estimated prevalence of child sexual abuse. We conclude that many variables influence the reported prevalence of child sexual abuse among sexual minorities.

  16. Comparative analysis of the complete mitochondrial genomes of three geographical topmouth culter (Culter alburnus) groups and implications for their phylogenetics.

    Science.gov (United States)

    Shi, Jianwu; Wang, Dexia; Wang, Junhua; Sheng, Junqing; Peng, Kou; Hu, Beijuan; Zeng, Liugen; Xiao, Minghe; Hong, Yijiang

    2017-03-01

    Topmouth culter (C. alburnus) is an important commercial fish in China. We compared the nucleotide variations in the mtDNA genomes among three geographical groups of Culter alburnus: Liangzi Lake, Hubei Province (referred to as LZH); Taihu Lake, Jiangsu Province (TH); and Poyang Lake, Jiangxi Province (PYH). The similarity of whole mtDNA genomes ranged from 0.992 to 0.999. The similarity among 13 protein-coding genes, 2 rRNA genes, and the D-loop sequences was found to range from 0.982 to 0.996. This is useful data for future designing work for making specific molecular marker for distinguishing individuals of C. alburnus from the three geographical groups. An extended termination-associated sequence (ETAS) and several conserved blocks (CSB-F, CSB-E, CSB-D, CSB1, CSB2, and CSB3) were identified in the mtDNA control regions. A phylogenetic analysis shows a monophyletic relationship of the LZF-female and the LZF-male. However, the analysis also showed paraphyletic relationships for the other two geological groups. This result will be useful for the future breeding work of C. alburnus.

  17. Geographical information system (GIS) as a new tool to evaluate epidemiology based on spatial analysis and clinical outcomes in acromegaly.

    Science.gov (United States)

    Naves, Luciana Ansaneli; Porto, Lara Benigno; Rosa, João Willy Corrêa; Casulari, Luiz Augusto; Rosa, José Wilson Corrêa

    2015-02-01

    Geographical information systems (GIS) have emerged as a group of innovative software components useful for projects in epidemiology and planning in Health Care System. This is an original study to investigate environmental and geographical influences on epidemiology of acromegaly in Brazil. We aimed to validate a method to link an acromegaly registry with a GIS mapping program, to describe the spatial distribution of patients, to identify disease clusters and to evaluate if the access to Health Care could influence the outcome of the disease. Clinical data from 112 consecutive patients were collected and home addresses were plotted in the GIS software for spatial analysis. The buffer spatial distribution of patients living in Brasilia showed that 38.1% lived from 0.33 to 8.66 km, 17.7% from 8.67 to 18.06 km, 22.2% from 18.07 to 25.67 km and 22% from 25.68 to 36.70 km distant to the Reference Medical Center (RMC), and no unexpected clusters were identified. Migration of 26 patients from 11 others cities in different regions of the country was observed. Most of patients (64%) with adenomas bigger than 25 mm lived more than 20 km away from RMC, but no significant correlation between the distance from patient's home to the RMC and tumor diameter (r = 0.45 p = 0.20) nor for delay in diagnosis (r = 0.43 p = 0.30) was found. The geographical distribution of diagnosed cases did not impact in the latency of diagnosis or tumor size but the recognition of significant migration denotes that improvements in the medical assistance network are needed.

  18. Analysis of the Network of Protected Areas in China Based on a Geographic Perspective: Current Status, Issues and Integration

    Directory of Open Access Journals (Sweden)

    Mengtian Cao

    2015-11-01

    Full Text Available With the continued growth of protected areas (PAs in China in terms of the number, coverage and varieties of protected objects, how to efficiently manage the protected areas to ensure both resource protection and environmental protection has become a crucial research question. By applying a geographic perspective in an analysis of the development and evolution of protected areas in China, this paper presents the results of an analysis focused on the status and the types of current approaches to the management of natural protected areas to reveal the problems that exist in their management and to further explore an integration strategy for the protected area network. It proposes that the future management of protected areas should prioritize their legal status, the sustainable livelihood of individuals living in close proximity to them, and the establishment of a unified database to achieve grid and information management of the protected areas.

  19. Geographic population structure analysis of worldwide human populations infers their biogeographical origins

    Science.gov (United States)

    Elhaik, Eran; Tatarinova, Tatiana; Chebotarev, Dmitri; Piras, Ignazio S.; Maria Calò, Carla; De Montis, Antonella; Atzori, Manuela; Marini, Monica; Tofanelli, Sergio; Francalacci, Paolo; Pagani, Luca; Tyler-Smith, Chris; Xue, Yali; Cucca, Francesco; Schurr, Theodore G.; Gaieski, Jill B.; Melendez, Carlalynne; Vilar, Miguel G.; Owings, Amanda C.; Gómez, Rocío; Fujita, Ricardo; Santos, Fabrício R.; Comas, David; Balanovsky, Oleg; Balanovska, Elena; Zalloua, Pierre; Soodyall, Himla; Pitchappan, Ramasamy; GaneshPrasad, ArunKumar; Hammer, Michael; Matisoo-Smith, Lisa; Wells, R. Spencer; Acosta, Oscar; Adhikarla, Syama; Adler, Christina J.; Bertranpetit, Jaume; Clarke, Andrew C.; Cooper, Alan; Der Sarkissian, Clio S. I.; Haak, Wolfgang; Haber, Marc; Jin, Li; Kaplan, Matthew E.; Li, Hui; Li, Shilin; Martínez-Cruz, Begoña; Merchant, Nirav C.; Mitchell, John R.; Parida, Laxmi; Platt, Daniel E.; Quintana-Murci, Lluis; Renfrew, Colin; Lacerda, Daniela R.; Royyuru, Ajay K.; Sandoval, Jose Raul; Santhakumari, Arun Varatharajan; Soria Hernanz, David F.; Swamikrishnan, Pandikumar; Ziegle, Janet S.

    2014-01-01

    The search for a method that utilizes biological information to predict humans’ place of origin has occupied scientists for millennia. Over the past four decades, scientists have employed genetic data in an effort to achieve this goal but with limited success. While biogeographical algorithms using next-generation sequencing data have achieved an accuracy of 700 km in Europe, they were inaccurate elsewhere. Here we describe the Geographic Population Structure (GPS) algorithm and demonstrate its accuracy with three data sets using 40,000–130,000 SNPs. GPS placed 83% of worldwide individuals in their country of origin. Applied to over 200 Sardinians villagers, GPS placed a quarter of them in their villages and most of the rest within 50 km of their villages. GPS’s accuracy and power to infer the biogeography of worldwide individuals down to their country or, in some cases, village, of origin, underscores the promise of admixture-based methods for biogeography and has ramifications for genetic ancestry testing. PMID:24781250

  20. A geographical analysis of speech-language pathology services to support multilingual children.

    Science.gov (United States)

    Verdon, Sarah; McLeod, Sharynne; McDonald, Simon

    2014-06-01

    The speech-language pathology workforce strives to provide equitable, quality services to multilingual people. However, the extent to which this is being achieved is unknown. Participants in this study were 2849 members of Speech Pathology Australia and 4386 children in the Birth cohort of the Longitudinal Study of Australian Children (LSAC). Statistical and geospatial analyses were undertaken to identify the linguistic diversity and geographical distribution of Australian speech-language pathology services and Australian children. One fifth of services offered by Speech Pathology Australia members (20.2%) were available in a language other than English. Services were most commonly offered in Australian Sign Language (Auslan) (4.3%), French (3.1%), Italian (2.2%), Greek (1.6%), and Cantonese (1.5%). Among 4-5-year-old children in the nationally representative LSAC, 15.3% regularly spoke and/or understood a language other than English. The most common languages spoken by the children were Arabic (1.5%), Italian (1.2%), Greek (0.9%), Spanish (0.9%), and Vietnamese (0.9%). There was a mismatch between the location of and languages in which multilingual services were offered, and the location of and languages spoken by children. These findings highlight the need for SLPs to be culturally competent in providing equitable services to all clients, regardless of the languages they speak.

  1. Analysis of the Correlation between the Geographical Distribution of Populus euphratica Oliv. and the Climatic Environment

    Institute of Scientific and Technical Information of China (English)

    Yinke YANG; Zhenglong YAN

    2012-01-01

    [Objective] This research was to study the correlation regional climatic characteristics and changing geographic distribution of Populus euphratica Oily. (Sali- caceae), as well as the adaption of Populus euphratica Oliv. to the climatic environ- ment. [Method] The climatic characteristics, water source, groundwater and soil type in the distribution regions of Populus euphratica Oliv. and the effect of long-term hu- man activities were comprehensively analyzed based an overview of Populus eu- phratica Oliv. and its distribution. [Result] Specific regional climatic characteristics and long term human activities are the principle determinants for the growth of Populus euphratica Oliv. The change of leaf shape is a distinct feature of Populus euphratica Oliv. in adapting to the climatic environment. Populus euphratica Oliv. withstands various environmental stresses by means of in vivo synthesis, transport and conver- sion of secondary phenolic metabolites. Effective protection and rehabilitation mea- sures, and ecological water transport have obvious effect on the restoration and re- construction of damaged ecological environment of Populus euphratica oasis. [Con- clusion] This study is of great significance for the restoration of ecological environ- ment in the arid inland regions, north-west China.

  2. A Geographic Information-Assisted Temporal Mixture Analysis for Addressing the Issue of Endmember Class and Endmember Spectra Variability

    Science.gov (United States)

    Li, Wenliang; Wu, Changshan

    2017-01-01

    Spectral mixture analysis (SMA) is a common approach for parameterizing biophysical fractions of urban environment and widely applied in many fields. For successful SMA, the selection of endmember class and corresponding spectra has been assumed as the most important step. Thanks to the spatial heterogeneity of natural and urban landscapes, the variability of endmember class and corresponding spectra has been widely considered as the profound error source in SMA. To address the challenging problems, we proposed a geographic information-assisted temporal mixture analysis (GATMA). Specifically, a logistic regression analysis was applied to analyze the relationship between land use/land covers and surrounding socio-economic factors, and a classification tree method was used to identify the present status of endmember classes throughout the whole study area. Furthermore, an ordinary kriging analysis was employed to generate a spatially varying endmember spectra at all pixels in the remote sensing image. As a consequence, a fully constrained temporal mixture analysis was conducted for examining the fractional land use land covers. Results show that the proposed GATMA achieved a promising accuracy with an RMSE of 6.81%, SE of 1.29% and MAE of 2.6%. In addition, comparative analysis result illustrates that a significant accuracy improvement has been found in the whole study area and both developed and less developed areas, and this demonstrates that the variability of endmember class and endmember spectra is essential for unmixing analysis. PMID:28335464

  3. A systematic review and meta-analysis of Hirschsprung's disease presenting after childhood.

    LENUS (Irish Health Repository)

    Doodnath, Reshma

    2012-02-01

    BACKGROUND: Hirschsprung\\'s disease (HD) is characterised by an absence of ganglion cells in the distal bowel, beginning at the internal sphincter and extending proximally to varying distances. It is usually diagnosed in the newborn period, with usual presentation of delayed passage of meconium and abdominal distension, with or without bilious vomiting. HD in adults is rare and is thus often undiagnosed or misdiagnosed. The purpose of this meta-analysis was to review the presentation, treatment and clinical outcome of HD presenting after childhood. METHODS: A systematic review and meta-analysis of all cases of HD presenting after childhood in the English literature was performed from 1950 to 2009. Detailed information regarding demographics, clinical presentation and methods of diagnosis, surgical procedure, complications and the outcome at time of follow up was recorded. RESULTS: There were 490 cases of HD presenting after childhood in the English literature, 341 (69.5%) males, 129 (26.4%) females and 20 (4.1%) cases where gender was not specified. As much as 390 (79.6%) were confined to the rectum, 60 (12.3%) had recto-sigmoid disease, 4 (0.8%) had disease extending to the descending colon and there were 2 (0.4%) cases that extended to the transverse colon and 2 (0.4%) cases of total colonic disease. The extent of disease was not specified in the remaining 32 (6.5%) cases. A total of 49 (10%) patients had the Swenson procedure, 231 (47.2%) patients had the Duhamel procedure, 40 (8.2%) patients had the Soave procedure, 45 (9.2%) patients had a myectomy only, 3 (0.6%) patients had a myectomy combined with colectomy, 14 (2.9%) patients had a myectomy combined with anterior resection. As much as 26 (5.3%) patients had a lower anterior resection (LAR), 28 (5.7%) patients had LAR combined with colectomy, 10 (2%) patients had a colectomy, 1 (0.2%) patient had an anopexy and 4 (0.9%) patients had a colostomy only. A total of 13 (2.7%) patients refused surgery and

  4. Family income trajectory during childhood is associated with adiposity in adolescence: a latent class growth analysis

    Directory of Open Access Journals (Sweden)

    Kendzor Darla E

    2012-08-01

    Full Text Available Abstract Background Childhood socioeconomic disadvantage has been linked with obesity in cross-sectional research, although less is known about how changes in socioeconomic status influence the development of obesity. Researchers have hypothesized that upward socioeconomic mobility may attenuate the health effects of earlier socioeconomic disadvantage; while downward socioeconomic mobility might have a negative influence on health despite relative socioeconomic advantages at earlier stages. The purpose of the current study was to characterize trajectories of family income during childhood, and to evaluate the influence of these trajectories on adiposity at age 15. Methods Data were collected as part of the Study of Early Child Care and Youth Development (SECCYD between 1991 and 2007 at 10 sites across the United States. A latent class growth analysis (LCGA was conducted to identify trajectories of family income from birth to 15 years of age. Analyses of covariance (ANCOVAs were conducted to determine whether measures of adiposity differed by trajectory, while controlling for relevant covariates. Results The LCGA supported a 5-class trajectory model, which included two stable, one downward, and two upward trajectories. ANCOVAs indicated that BMI percentile, waist circumference, and skinfold thicknesses at age 15 differed significantly by trajectory, such that those who experienced downward mobility or stable low income had greater adiposity relative to the more advantaged trajectories. Conversely, upwardly mobile children and those with consistently adequate incomes had similar and more positive outcomes relative to the most disadvantaged trajectories. Conclusions Findings suggest that promoting upward socioeconomic mobility among disadvantaged families may have a positive impact on obesity-related outcomes in adolescence.

  5. Geographical Tatoos

    Directory of Open Access Journals (Sweden)

    Valéria Cazetta

    2014-08-01

    Full Text Available The article deals with maps tattooed on bodies. My interest in studying the corporeality is inserted in a broader project entitled Geographies and (in Bodies. There is several published research on tattoos, but none in particular about tattooed maps. However some of these works interested me because they present important discussions in contemporary about body modification that helped me locate the body modifications most within the culture than on the nature. At this time, I looked at pictures of geographical tattoos available in several sites of the internet.

  6. Using Fuzzy Analytic Hierarchy Process multicriteria and Geographical information system for coastal vulnerability analysis in Morocco: The case of Mohammedia

    Science.gov (United States)

    Tahri, Meryem; Maanan, Mohamed; Hakdaoui, Mustapha

    2016-04-01

    This paper shows a method to assess the vulnerability of coastal risks such as coastal erosion or submarine applying Fuzzy Analytic Hierarchy Process (FAHP) and spatial analysis techniques with Geographic Information System (GIS). The coast of the Mohammedia located in Morocco was chosen as the study site to implement and validate the proposed framework by applying a GIS-FAHP based methodology. The coastal risk vulnerability mapping follows multi-parametric causative factors as sea level rise, significant wave height, tidal range, coastal erosion, elevation, geomorphology and distance to an urban area. The Fuzzy Analytic Hierarchy Process methodology enables the calculation of corresponding criteria weights. The result shows that the coastline of the Mohammedia is characterized by a moderate, high and very high level of vulnerability to coastal risk. The high vulnerability areas are situated in the east at Monika and Sablette beaches. This technical approach is based on the efficiency of the Geographic Information System tool based on Fuzzy Analytical Hierarchy Process to help decision maker to find optimal strategies to minimize coastal risks.

  7. Maternal benzene exposure during pregnancy and risk of childhood acute lymphoblastic leukemia: a meta-analysis of epidemiologic studies.

    Directory of Open Access Journals (Sweden)

    Yanfeng Zhou

    Full Text Available The prevalence of childhood leukemia is increasing rapidly all over the world. However, studies on maternal benzene exposure during pregnancy and childhood acute lymphoblastic leukemia (ALL have not been systematically assessed. Therefore, we performed a meta-analysis to investigate the association between maternal solvent, paint, petroleum exposure, and smoking during pregnancy and risk of childhood ALL.Relevant studies up to September 1st, 2013 were identified by searching the PubMed, EMBASE, Cochrane library and the Web of Science databases. The effects were pooled using either fixed or random effect models based on the heterogeneity of the studies.Twenty-eight case-control studies and one cohort study were included for analysis, with a total of 16,695 cases and 1,472,786 controls involved. Pooled odds ratio (OR with 95% confidence interval (CI for ALL was 1.25 (1.09, 1.45 for solvent, 1.23 (1.02, 1.47 for paint, 1.42 (1.10, 1.84 for petroleum exposure, and 0.99 (0.93, 1.06 for maternal smoking during pregnancy. No publication bias was found in this meta-analysis and consistent results were observed for subgroup and sensitivity analyses.Childhood ALL was associated with maternal solvent, paint, and petroleum exposure during pregnancy. No association was found between ALL and maternal smoking during pregnancy. Avoidance of maternal occupational and environmental benzene exposure during pregnancy could contribute to a decrease in the risk of childhood ALL.

  8. Is Sensory Over-Responsivity Distinguishable from Childhood Behavior Problems? A Phenotypic and Genetic Analysis

    Science.gov (United States)

    Van Hulle, Carol A.; Schmidt, Nicole L.; Goldsmith, H. Hill

    2012-01-01

    Background: Although impaired sensory processing accompanies various clinical conditions, the question of its status as an independent disorder remains open. Our goal was to delineate the comorbidity (or lack thereof) between childhood psychopathology and sensory over-responsivity (SOR) in middle childhood using phenotypic and behavior-genetic…

  9. Whose Expertise?: An Analysis of Advice Giving in Early Childhood Parent-Teacher Conferences

    Science.gov (United States)

    Cheatham, Gregory A.; Ostrosky, Michaelene M.

    2011-01-01

    Early childhood and early childhood special education programs have a focus on parent-educator partnerships. Parent-teacher conferences are a context for these partnerships, and advice giving is one type of exchange occurring within conferences. Parent-teacher conference advice was investigated through participant interviews and the methodology of…

  10. Analysis of terrains suitable for tourism and recreation by using geographic information system (GIS).

    Science.gov (United States)

    Aklıbaşında, Meliha; Bulut, Yahya

    2014-09-01

    The use and utilization areas of geographic information system (GIS) increase every day due to both enabling easiness in storing, updating, grouping, analyzing, correlating, and mapping of data about evaluation factors in planning studies and having quite low error margin depending on the accuracy of data stored. In fact, GIS is also used both in visualization and in various analyses in planning tourism terrains. In this study, the effectiveness of GIS on holistic evaluation of natural and cultural resources in planning tourism terrains was analyzed. Natural and cultural resources in Kayseri Yahyalı were quantified by using ArcGIS 9.3 software from GIS software; data were analyzed and potential tourism and recreation terrains, level of suitability, and rate of coverage were determined. As a result of the analyses, it was determined that 11.847 ha area (6,53%) was quite suitable for such kind of activities, 103.010 ha (56,77%) was suitable, 39.278 ha (21,65%) was less suitable, and 27.314 ha area (15,05%) was not suitable. In the next stage, landscape properties which are suitable for tourism and recreation were evaluated and landscape types were classified in the sense of their tourist attraction. It was determined that the water resources and valley landscapes were the basic sources of the tourism and recreation activities of Yahyalı, and it was determined that the landscape of the forest and mountain was important for variety of the tourism and recreation activities of Yahyalı.

  11. Spatial Analysis in Determination Of Flood Prone Areas Using Geographic Information System and Analytical Hierarchy Process at Sungai Sembrong's Catchment

    Science.gov (United States)

    Bukari, S. M.; Ahmad, M. A.; Wai, T. L.; Kaamin, M.; Alimin, N.

    2016-07-01

    Floods that struck Johor state in 2006 and 2007 and the East Coastal in 2014 have triggered a greatly impact to the flood management here in Malaysia. Accordingly, this study conducted to determine potential areas of flooding, especially in Batu Pahat district since it faces terrifying experienced with heavy flood. This objective is archived by using the application of Geographic Information Systems (GIS) on study area of flood risk location at the watershed area of Sungai Sembrong. GIS functions as spatial analysis is capable to produce new information based on analysis of data stored in the system. Meanwhile the Analytical Hierarchy Process (AHP) was used as a method for setting up in decision making concerning the existing data. By using AHP method, preparation and position of the criteria and parameters required in GIS are neater and easier to analyze. Through this study, a flood prone area in the watershed of Sungai Sembrong was identified with the help of GIS and AHP. Analysis was conducted to test two different cell sizes, which are 30 and 5. The analysis of flood prone areas were tested on both cell sizes with two different water levels and the results of the analysis were displayed by GIS. Therefore, the use of AHP and GIS are effective and able to determine the potential flood plain areas in the watershed area of Sungai Sembrong.

  12. Childhood growth trajectories according to combinations of pregestational weight status and maternal smoking during pregnancy: a multilevel analysis.

    Science.gov (United States)

    Suzuki, Kohta; Sato, Miri; Zheng, Wei; Shinohara, Ryoji; Yokomichi, Hiroshi; Yamagata, Zentaro

    2015-01-01

    Pregestational weight status and maternal smoking during pregnancy are significantly associated with fetal and childhood growth. However, few studies have examined associations between childhood growth and combinations of these factors using multilevel analysis. This study aimed to describe differences in childhood growth trajectories according to these combinations, using data from a prospective cohort study in Japan. The study participants were 1,973 women and their singletons, who were born between April 1, 1991 and March 31, 2003. Children were categorized according to whether they were born to normal-weight, nonsmoking mothers (NN); normal-weight, smoking mothers (NS); underweight, nonsmoking mothers (UN); underweight, smoking mothers (US); overweight, nonsmoking mothers (ON); or overweight, smoking mothers (OS). Birth weight and anthropometric data were collected from 1,965 children at birth (99.6%), 1,655 aged 3 (83.9%), 1,527 aged 5 (77.4%), 1,497 aged 7-8 (75.9%), and 1,501 aged 9-10 (76.1%). Multilevel analysis examining both individual and age as different level variables according to sex was used to describe the trajectories of body mass index z scores for statistical analyses. Although children of the OS group were the leanest at birth, their body mass indices had increased rapidly by 3 years of age. Moreover, body mass index was also likely to increase in boys in the NS and ON groups. A different trend was observed in girls. Body mass index decreased from 5 years of age in girls in the US group. There were no remarkable differences in body mass index trajectories between children in the other groups. In conclusion, childhood growth trajectories differed according to combinations of pregestational weight status and maternal smoking during pregnancy. Further, there were sex-related differences in the associations between childhood growth and factor combinations.

  13. Effect of Climate Factors on the Childhood Pneumonia in Papua New Guinea: A Time-Series Analysis.

    Science.gov (United States)

    Kim, Jinseob; Kim, Jong-Hun; Cheong, Hae-Kwan; Kim, Ho; Honda, Yasushi; Ha, Mina; Hashizume, Masahiro; Kolam, Joel; Inape, Kasis

    2016-02-15

    This study aimed to assess the association between climate factors and the incidence of childhood pneumonia in Papua New Guinea quantitatively and to evaluate the variability of the effect size according to their geographic properties. The pneumonia incidence in children under five-year and meteorological factors were obtained from six areas, including monthly rainfall and the monthly average daily maximum temperatures during the period from 1997 to 2006 from national health surveillance data. A generalized linear model was applied to measure the effect size of local and regional climate factor. The pooled risk of pneumonia in children per every 10 mm increase of rainfall was 0.24% (95% confidence interval: -0.01%-0.50%), and risk per every 1 °C increase of the monthly mean of the maximum daily temperatures was 4.88% (95% CI: 1.57-8.30). Southern oscillation index and dipole mode index showed an overall negative effect on childhood pneumonia incidence, -0.57% and -4.30%, respectively, and the risk of pneumonia was higher in the dry season than in the rainy season (pooled effect: 12.08%). There was a variability in the relationship between climate factors and pneumonia which is assumed to reflect distribution of the determinants of and vulnerability to pneumonia in the community.

  14. The integration of a LANDSAT analysis capability with a geographic information system

    Science.gov (United States)

    Nordstrand, E. A.

    1981-01-01

    The integration of LANDSAT data was achieved through the development of a flexible, compatible analysis tool and using an existing data base to select the usable data from a LANDSAT analysis. The software package allows manipulation of grid cell data plus the flexibility to allow the user to include FORTRAN statements for special functions. Using this combination of capabilities the user can classify a LANDSAT image and then selectivity merge the results with other data that may exist for the study area.

  15. Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic sites

    Directory of Open Access Journals (Sweden)

    Henry Marie-Claire

    2007-12-01

    Full Text Available Abstract Background The antimalarial drug atovaquone specifically targets Plasmodium falciparum cytochrome b (Pfcytb, a mitochondrial gene with uniparental inheritance. Cases of resistance to atovaquone associated with mutant Pfcytb have been reported, justifying efforts to better document the natural polymorphism of this gene. To this end, a large molecular survey was conducted in several malaria endemic areas where atovaquone was not yet in regular use. Methods The polymorphism of the Pfcytb was analysed by direct sequencing of PCR products corresponding to the full length coding region. Sequence was generated for 671 isolates originating from three continents: Africa (Senegal, Ivory Coast, Central African Republic and Madagascar, Asia (Cambodia and South America (French Guiana. Results Overall, 11 polymorphic sites were observed, of which eight were novel mutations. There was a large disparity in the geographic distribution of the mutants. All isolates from Senegal, Central African Republic and Madagascar displayed a Camp/3D7 wild type Pfcytb sequence, as did most samples originating from Cambodia and Ivory Coast. One synonymous (t759a at codon V253V and two non-synonymous (t553g and a581g at codons F185V and H194R, respectively singletons were detected in Ivory Coast. Likewise, two synonymous (a126t and c793t at codons -T42T and L265L, respectively singletons were observed in Cambodia. In contrast, seven mutated sites, affecting seven codons and defining four mutant haplotypes were observed in French Guiana. The wild type allele was observed in only 14% of the French Guiana isolates. The synonymous c688t mutation at position L230L was highly prevalent; the most frequent allele was the c688t single mutant, observed in 84% of the isolates. The other alleles were singletons (a126t/a165c, a4g/a20t/a1024c and a20t/t341c/c688t corresponding to T42T/S55S, N2D/N71I/I342L, N71I/L114S/L230L, respectively" please replace with ' corresponding to T42T

  16. Geographic Information Systems.

    Science.gov (United States)

    Wieczorek, William F; Delmerico, Alan M

    2009-01-01

    This chapter presents an overview of the development, capabilities, and utilization of geographic information systems (GIS). There are nearly an unlimited number of applications that are relevant to GIS because virtually all human interactions, natural and man-made features, resources, and populations have a geographic component. Everything happens somewhere and the location often has a role that affects what occurs. This role is often called spatial dependence or spatial autocorrelation, which exists when a phenomenon is not randomly geographically distributed. GIS has a number of key capabilities that are needed to conduct a spatial analysis to assess this spatial dependence. This chapter presents these capabilities (e.g., georeferencing, adjacency/distance measures, overlays) and provides a case study to illustrate how GIS can be used for both research and planning. Although GIS has developed into a relatively mature application for basic functions, development is needed to more seamlessly integrate spatial statistics and models.The issue of location, especially the geography of human activities, interactions between humanity and nature, and the distribution and location of natural resources and features, is one of the most basic elements of scientific inquiry. Conceptualizations and physical maps of geographic space have existed since the beginning of time because all human activity takes place in a geographic context. Representing objects in space, basically where things are located, is a critical aspect of the natural, social, and applied sciences. Throughout history there have been many methods of characterizing geographic space, especially maps created by artists, mariners, and others eventually leading to the development of the field of cartography. It is no surprise that the digital age has launched a major effort to utilize geographic data, but not just as maps. A geographic information system (GIS) facilitates the collection, analysis, and reporting of

  17. Childhood Schizophrenia

    Science.gov (United States)

    Childhood schizophrenia Overview By Mayo Clinic Staff Childhood schizophrenia is an uncommon but severe mental disorder in which children interpret reality abnormally. Schizophrenia involves a range of problems with thinking (cognitive), ...

  18. Assessment of the olive territory thrung bio-morphological and geographical analysis

    Directory of Open Access Journals (Sweden)

    Hairi Ismaili

    2013-12-01

    Full Text Available Autochthonous germoplasm of the olive with 156 accessions, (O europaea L. ssp. Sativa Hoffm, ssp. O. Oleaster Hoffm, and ssp. Sylvestris, has been analyzed with biological valences of the species (catminate code and D-GIS (Bioclim / Domain, to identify diversity and suitability of the territory for olive cultivation. Cartography with spatial analysis detects areas of different height diversity levels. (a lot of estimators and variability. In the explored space, 20-37% of the territory resulted excellent for olive cultivation. In the analysis of spatial density, the area of Albania has two major hearths: the Ionian and Adriatic Hearth. In general, 21 genotypes resulted synonyms of 7 standard cv, whereas 21 genotypes resulted homonymous. PCA between correlation matrices of all variables, classified 16 unrelated variables explaining >95 % of total variance. PCoA indexes eigevectors positioned genotypes and their characters according to their degree of variability in negative or positive space. (Axes, x, y and z.

  19. Geographic structure of Plasmodium vivax: microsatellite analysis of parasite populations from Sri Lanka, Myanmar, and Ethiopia

    DEFF Research Database (Denmark)

    Gunawardena, Sharmini; Karunaweera, Nadira D; Ferreira, Marcelo U;

    2010-01-01

    , Myanmar, and Ethiopia using 12 trinucleotide and tetranucleotide microsatellite markers. All three parasite populations were highly polymorphic with 3-44 alleles per locus. Approximately 65% were multiple-clone infections. Mean genetic diversity (H(E)) was 0.7517 in Ethiopia, 0.8450 in Myanmar, and 0...... as a model identified 78.2% of isolates accurately as being African or Asian. Microsatellite analysis is a useful tool for mapping short-term outbreaks of malaria and for predicting ancestry....

  20. Geographic Distribution of Radiologists and Utilization of Teleradiology in Japan: A Longitudinal Analysis Based on National Census Data.

    Directory of Open Access Journals (Sweden)

    Masatoshi Matsumoto

    Full Text Available Japan has the most CT and MRI scanners per unit population in the world, and as these technologies spread, their geographic distribution is becoming equalized. In contrast, the number of radiologists per unit population in Japan is the lowest among OECD countries and their geographic distribution is unknown. Likewise, little is known about the use of teleradiology, which can compensate for the uneven distribution of radiologists.Based on the Survey of Physicians, Dentists and Pharmacists and the Static Survey of Medical Institutions by the Ministry of Health, Labour and Welfare, a dataset of radiologists and CT and MRI utilizations in each of Japan's 1811 municipalities was created. The inter-municipality equity of the number of radiologists was evaluated using Gini coefficient. Logistic regression analysis, based on Static Survey data, was performed to evaluate the association between hospital location and teleradiology use.Between 2006 and 2012 the number of radiologists increased by 21.7%, but the Gini coefficient remained unchanged. The number of radiologists per 1,000 CT (MRI utilizations decreased by 17.9% (1.0%; the number was highest in metropolis and lowest in town/village and the disparity has widened from 1.9 to 2.2 (1.6 to 2.0 times. The number of hospitals and clinics using teleradiology has increased (by 69.6% and 18.1%, respectively. Hospitals located in towns/villages (odds ratio 1.61; 95% confidence interval 1.26-2.07 were more likely to use teleradiology than those in metropolises.Contrary to the CT and MRI distributions, radiologist distribution has not been evened out by the increase in their number; in other words, the distribution of radiologists was not affected by market-derived spatial competition force. As a consequence, the gap of the radiologist shortage between urban and rural areas is increasing. Teleradiology, which is one way to ameliorate this gap, should be encouraged.

  1. Analysis of Debris Flow Kuranji River in Padang City Using Rainfall Data, Remote Sensing and Geographic Information System

    Science.gov (United States)

    Umar, Z.; Mohd Akib, W. A. A. Wan; Ahmad, A.

    2014-02-01

    Flash flood is the most common environmental hazard worldwide. This phenomenon is usually occurs due to intense and prolonged rainfall spells on saturated ground. When there is a rapid rise in water levels and high flow-velocities of the stream occur, the channel overflows and the result is a flash flood. Flash floods normally cause a dangerous wall of roaring water carrying rocks, mud and other debris. On Tuesday, July 24, 2012 at 18:00 pm, a flash flood (debris flow) struck Kuranji River whereby 19 urban villages in seven (7) sub-districts in the city of Padang were affected by this flood disaster. The temporary loss estimated is 40 Billion US Dollar reported by the West Sumatra Provincial Government due to many damages of the built environment infrastructures. This include damaged houses of 878 units, mosque 15 units, irrigation damaged 12 units, bridges 6 units, schools 2 units and health posts 1 unit. Generally, widely used methods for making a landslide study are Geographic Information System (GIS) and Remote Sensing techniques. The landslide information extracted from remotely sensed products is mainly related to morphology, vegetation and hydrologic conditions of a slope. While GIS is used to create a database, data management, data display and to analyze data such as thematic maps of land use/land cover, normalized difference vegetation index (NDVI), rainfall data and soil texture. This paper highlights the analysis of the condition of the Watershed Kuranji River experiencing flash floods, using remote sensing satellite image of Landsat ETM 7 in 2009 and 2012 and Geographic Information System (GIS). Furthermore, the data was analyzed to determine whether this flash flood occurred due to extreme rain or collapse of existing natural dams in the upstream of the Kuranji River.

  2. Applications of Remote Sensing and GIS(Geographic Information System) in Crime Analysis of Gujranwala City.

    Science.gov (United States)

    Munawar, Iqra

    2016-07-01

    Crime mapping is a dynamic process. It can be used to assist all stages of the problem solving process. Mapping crime can help police protect citizens more effectively. The decision to utilize a certain type of map or design element may change based on the purpose of a map, the audience or the available data. If the purpose of the crime analysis map is to assist in the identification of a particular problem, selected data may be mapped to identify patterns of activity that have been previously undetected. The main objective of this research was to study the spatial distribution patterns of the four common crimes i.e Narcotics, Arms, Burglary and Robbery in Gujranwala City using spatial statistical techniques to identify the hotspots. Hotspots or location of clusters were identified using Getis-Ord Gi* Statistic. Crime analysis mapping can be used to conduct a comprehensive spatial analysis of the problem. Graphic presentations of such findings provide a powerful medium to communicate conditions, patterns and trends thus creating an avenue for analysts to bring about significant policy changes. Moreover Crime mapping also helps in the reduction of crime rate.

  3. Childhood obesity

    OpenAIRE

    Wilkinson, Justine; Howard, Simon

    2006-01-01

    Childhood obesity has important consequences for health and wellbeing both during childhood and also in later adult life. The rising prevalence of childhood obesity poses a major public health challenge in both developed and developing countries by increasing the burden of chronic non-communicable diseases. Despite the urgent need for effective preventative strategies, there remains disagreement over its definition due to a lack of evidence on the optimal cut-offs linking childhood BMI to dis...

  4. Malnutrition in remission of childhood cancers as assessed by bioelectric impedance analysis

    Directory of Open Access Journals (Sweden)

    M. V. Konovalova

    2014-07-01

    Full Text Available The results of our cross-sectional bioimpedance study of children aged 7–17 years cured of cancer during follow-up (patients’ group, n = 552, remission time range 0–15 years and of age-matched healthy controls (n = 1,500 show significant intergroup differences in body height and body composition parameters. The most pronounced alterations in the patients’ group were observed in standardized values of phase angle reflecting a sharp decrease in the percentage of metabolically active body cell mass in fat-free mass. Malnutrition, judged from the prevalence of obesity and low phase angle, was observed in 52.7 % of our patients reaching a maximum of 76.8 % in a subgroup of children with CNS tumors. In view of known association that exists between malnutrition and reduced tolerance to chemotherapy, increased susceptibility to infections and adverse outcomes rate, we recommend using bioimpedance analysis in remission of childhood cancers in order to monitoring and timely correction of nutritional state as well as for prevention of delayed cardiovascular risks.

  5. Malnutrition in remission of childhood cancers as assessed by bioelectric impedance analysis

    Directory of Open Access Journals (Sweden)

    M. V. Konovalova

    2012-01-01

    Full Text Available The results of our cross-sectional bioimpedance study of children aged 7–17 years cured of cancer during follow-up (patients’ group, n = 552, remission time range 0–15 years and of age-matched healthy controls (n = 1,500 show significant intergroup differences in body height and body composition parameters. The most pronounced alterations in the patients’ group were observed in standardized values of phase angle reflecting a sharp decrease in the percentage of metabolically active body cell mass in fat-free mass. Malnutrition, judged from the prevalence of obesity and low phase angle, was observed in 52.7 % of our patients reaching a maximum of 76.8 % in a subgroup of children with CNS tumors. In view of known association that exists between malnutrition and reduced tolerance to chemotherapy, increased susceptibility to infections and adverse outcomes rate, we recommend using bioimpedance analysis in remission of childhood cancers in order to monitoring and timely correction of nutritional state as well as for prevention of delayed cardiovascular risks.

  6. Prenatal maternal psychological stress and childhood asthma and wheezing: a meta-analysis.

    Science.gov (United States)

    van de Loo, Kim F E; van Gelder, Marleen M H J; Roukema, Jolt; Roeleveld, Nel; Merkus, Peter J F M; Verhaak, Christianne M

    2016-01-01

    The aim of this study was to systematically review and meta-analyse observational studies on prenatal maternal psychological stress and the subsequent development of asthma and wheezing in early childhood.All available published literature from 1960 until November 2013 was systematically searched through electronic databases (PubMed, Embase, PsycInfo and Web of Science). All observational studies assessing associations between any form of prenatal maternal psychological stress and respiratory morbidity in the child were included. Data extraction, quality assessment and meta-analyses were performed.The overall meta-analysis included 10 studies and showed that the prevalence of wheezing, asthma and other respiratory symptoms is higher in children of mothers who were exposed to or experienced some form of psychological stress during pregnancy than in mothers who did not (pooled OR 1.56 (95% CI 1.36-1.80)). Comparable results were observed in subgroup analyses of stress exposure, perceived stress, asthma and wheezing.This study demonstrates that prenatal maternal psychological stress is associated with respiratory morbidity, including asthma and wheezing in the child. Future studies examining the early origins of asthma and wheezing need to account for the impact of prenatal maternal stress.

  7. Targeted and nontargeted wine analysis by (1)h NMR spectroscopy combined with multivariate statistical analysis. Differentiation of important parameters: grape variety, geographical origin, year of vintage.

    Science.gov (United States)

    Godelmann, Rolf; Fang, Fang; Humpfer, Eberhard; Schütz, Birk; Bansbach, Melanie; Schäfer, Hartmut; Spraul, Manfred

    2013-06-12

    The authenticity, the grape variety, the geographical origin, and the year of vintage of wines produced in Germany were investigated by (1)H NMR spectroscopy in combination with several steps of multivariate data analysis including principal component analysis (PCA), linear discrimination analysis (LDA), and multivariate analysis of variance (MANOVA) together with cross-validation (CV) embedded in a Monte Carlo resampling approach (MC) and others. A total of about 600 wines were selected and carefully collected from five wine-growing areas in the southern and southwestern parts of Germany. Simultaneous saturation of the resonances of water and ethanol by application of a low-power eight-frequency band irradiation using shaped pulses allowed for high receiver gain settings and hence optimized signal-to-noise ratios. Correct prediction of classification of the grape varieties of Pinot noir, Lemberger, Pinot blanc/Pinot gris, Müller-Thurgau, Riesling, and Gewürztraminer of 95% in the wine panel was achieved. The classification of the vintage of all analyzed wines resulted in correct predictions of 97 and 96%, respectively, for vintage 2008 (n = 318) and 2009 (n = 265). The geographic origin of all wines from the largest German wine-producing regions, Rheinpfalz, Rheinhessen, Mosel, Baden, and Württemberg, could be predicted 89% correctly on average. Each NMR spectrum could be regarded as the individual "fingerprint" of a wine sample, which includes information about variety, origin, vintage, physiological state, technological treatment, and others.

  8. Time-Series Analysis of Continuously Monitored Blood Glucose: The Impacts of Geographic and Daily Lifestyle Factors

    Directory of Open Access Journals (Sweden)

    Sean T. Doherty

    2015-01-01

    Full Text Available Type 2 diabetes is known to be associated with environmental, behavioral, and lifestyle factors. However, the actual impacts of these factors on blood glucose (BG variation throughout the day have remained relatively unexplored. Continuous blood glucose monitors combined with human activity tracking technologies afford new opportunities for exploration in a naturalistic setting. Data from a study of 40 patients with diabetes is utilized in this paper, including continuously monitored BG, food/medicine intake, and patient activity/location tracked using global positioning systems over a 4-day period. Standard linear regression and more disaggregated time-series analysis using autoregressive integrated moving average (ARIMA are used to explore patient BG variation throughout the day and over space. The ARIMA models revealed a wide variety of BG correlating factors related to specific activity types, locations (especially those far from home, and travel modes, although the impacts were highly personal. Traditional variables related to food intake and medications were less often significant. Overall, the time-series analysis revealed considerable patient-by-patient variation in the effects of geographic and daily lifestyle factors. We would suggest that maps of BG spatial variation or an interactive messaging system could provide new tools to engage patients and highlight potential risk factors.

  9. Characterizing the magnitude of the relation between self-reported childhood parentification and adult psychopathology: a meta-analysis.

    Science.gov (United States)

    Hooper, Lisa M; Decoster, Jamie; White, Nyshetia; Voltz, Mukesha L

    2011-10-01

    Several decades of research have shown that people who experience parentification in childhood are at an increased risk of experiencing psychopathology in adulthood. A meta-analysis was conducted to examine the magnitude of the relation between self-reported parentification experienced in childhood and psychopathology evidenced in adulthood. Results from 12 nonoverlapping studies (N = 2,472), which were conducted between 1984 and 2010, revealed a small significant but reliable effect (r = .14; 95% confidence interval = .10 to .18). Moderator analyses were performed to explore possible explanations for the variance evidenced between parentification and psychopathology. Moderators that were examined include population factors, methodological factors, and type of psychopathology. The present findings indicate that four factors-types of psychopathology, type of sample, race, and parentification measure used-moderated the relation between parentification and psychopathology. The meta-analytic findings that emerged highlight the need for additional empirical research. Possible explanations and clinical

  10. Bird diversity, birdwatching tourism and conservation in Peru: a geographic analysis.

    Science.gov (United States)

    Puhakka, Liisa; Salo, Matti; Sääksjärvi, Ilari E

    2011-01-01

    In the face of the continuing global biodiversity loss, it is important not only to assess the need for conservation, through e.g. gap analyses, but also to seek practical solutions for protecting biodiversity. Environmentally and socially sustainable tourism can be one such solution. We present a method to spatially link data on conservation needs and tourism-based economic opportunities, using bird-related tourism in Peru as an example. Our analysis highlighted areas in Peru where potential for such projects could be particularly high. Several areas within the central and northern Andean regions, as well as within the lowland Amazonian regions of Madre de Dios and Loreto emerge as promising for this type of activity. Mechanisms to implement conservation in these areas include e.g. conservation and ecotourism concessions, private conservation areas, and conservation easements. Some of these mechanisms also offer opportunities for local communities seeking to secure their traditional land ownership and use rights. (Spanish language abstract, Abstract S1).

  11. Introduction to the GEOBIA 2010 special issue: From pixels to geographic objects in remote sensing image analysis

    Science.gov (United States)

    Addink, Elisabeth A.; Van Coillie, Frieke M. B.; De Jong, Steven M.

    2012-04-01

    Traditional image analysis methods are mostly pixel-based and use the spectral differences of landscape elements at the Earth surface to classify these elements or to extract element properties from the Earth Observation image. Geographic object-based image analysis (GEOBIA) has received considerable attention over the past 15 years for analyzing and interpreting remote sensing imagery. In contrast to traditional image analysis, GEOBIA works more like the human eye-brain combination does. The latter uses the object's color (spectral information), size, texture, shape and occurrence to other image objects to interpret and analyze what we see. GEOBIA starts by segmenting the image grouping together pixels into objects and next uses a wide range of object properties to classify the objects or to extract object's properties from the image. Significant advances and improvements in image analysis and interpretation are made thanks to GEOBIA. In June 2010 the third conference on GEOBIA took place at the Ghent University after successful previous meetings in Calgary (2008) and Salzburg (2006). This special issue presents a selection of the 2010 conference papers that are worked out as full research papers for JAG. The papers cover GEOBIA applications as well as innovative methods and techniques. The topics range from vegetation mapping, forest parameter estimation, tree crown identification, urban mapping, land cover change, feature selection methods and the effects of image compression on segmentation. From the original 94 conference papers, 26 full research manuscripts were submitted; nine papers were selected and are presented in this special issue. Selection was done on the basis of quality and topic of the studies. The next GEOBIA conference will take place in Rio de Janeiro from 7 to 9 May 2012 where we hope to welcome even more scientists working in the field of GEOBIA.

  12. Open defecation and childhood stunting in India: an ecological analysis of new data from 112 districts.

    Science.gov (United States)

    Spears, Dean; Ghosh, Arabinda; Cumming, Oliver

    2013-01-01

    Poor sanitation remains a major public health concern linked to several important health outcomes; emerging evidence indicates a link to childhood stunting. In India over half of the population defecates in the open; the prevalence of stunting remains very high. Recently published data on levels of stunting in 112 districts of India provide an opportunity to explore the relationship between levels of open defecation and stunting within this population. We conducted an ecological regression analysis to assess the association between the prevalence of open defecation and stunting after adjustment for potential confounding factors. Data from the 2011 HUNGaMA survey was used for the outcome of interest, stunting; data from the 2011 Indian Census for the same districts was used for the exposure of interest, open defecation. After adjustment for various potential confounding factors--including socio-economic status, maternal education and calorie availability--a 10 percent increase in open defecation was associated with a 0.7 percentage point increase in both stunting and severe stunting. Differences in open defecation can statistically account for 35 to 55 percent of the average difference in stunting between districts identified as low-performing and high-performing in the HUNGaMA data. In addition, using a Monte Carlo simulation, we explored the effect on statistical power of the common practice of dichotomizing continuous height data into binary stunting indicators. Our simulation showed that dichotomization of height sacrifices statistical power, suggesting that our estimate of the association between open defecation and stunting may be a lower bound. Whilst our analysis is ecological and therefore vulnerable to residual confounding, these findings use the most recently collected large-scale data from India to add to a growing body of suggestive evidence for an effect of poor sanitation on human growth. New intervention studies, currently underway, may shed more

  13. Risks to Colombian amphibian fauna from cultivation of coca (Erythroxylum coca): a geographical analysis.

    Science.gov (United States)

    Lynch, J D; Arroyo, S B

    2009-01-01

    The Colombian amphibian fauna is among the richest known in the world, with about 20 species of salamanders (order Caudata), 35 of the limbless caecilians (order Gymnophiona), and more than 700 species of frogs and toads (order Anura) recorded from localities within the country. The potential effects of exposure to glyphosate on amphibians arising from production of illegal crops (coca) were examined. The analysis was based on (1) behavior and ecology of species and (2) proximities of actual museum records to localities in which illegal crops are being grown and the subset of those that have been sprayed with glyphosate. Based on data on the location of amphibians collected in Colombia, records were obtained for 193 species (28% of the national diversity) of frogs and toads found in localities within 10 km of areas where coca is grown. Further analyses with ARC MAP software allowed for measurement of the direct distance separating collection locations for frogs, known coca fields, and areas where aerial spraying was being conducted. Records in or near coca fields included data for 11 of 13 families of frogs and toads known to be present in Colombia. Only Ceratophryidae and Pipidae were not reported from these locations and appear not to be at risk. For eight species (Dendrobates truncatus, Craugastor raniformis, Pristimantis gaigeae, Smilisca phaeota, Elachistocleis ovale, Hypsiboas crepitans, Trachycephalus venulosus, and Pseudis paradoxa) selected to represent several habitat preferences and life-cycle strategies, large areas of their distributions lie outside coca production regions and their populations as a whole are at low risk. For a limited number of species that barely enter Colombian territory, the consequences of coca production may be more serious and may have placed several species of frogs at risk. These include Ameerega bilingua, Dendropsophus bifurcus, Pristimantis colomai, P. degener, P. diadematus, P. quaquaversus, P. variabilis, and

  14. Recent Coverage of Early Childhood Education Approaches in Open Access Early Childhood Journals

    Science.gov (United States)

    Keskin, Burhanettin

    2016-01-01

    A content analysis of the coverage of the major approaches to early childhood education in the early childhood research journals, published between 2010 and 2014, that are early childhood research oriented and have free online access were investigated. Among 21 journals in early childhood education, two journals were selected for the content…

  15. Minimal Residual Disease Evaluation in Childhood Acute Lymphoblastic Leukemia: An Economic Analysis

    Science.gov (United States)

    Gajic-Veljanoski, O.; Pham, B.; Pechlivanoglou, P.; Krahn, M.; Higgins, Caroline; Bielecki, Joanna

    2016-01-01

    Background Minimal residual disease (MRD) testing by higher performance techniques such as flow cytometry and polymerase chain reaction (PCR) can be used to detect the proportion of remaining leukemic cells in bone marrow or peripheral blood during and after the first phases of chemotherapy in children with acute lymphoblastic leukemia (ALL). The results of MRD testing are used to reclassify these patients and guide changes in treatment according to their future risk of relapse. We conducted a systematic review of the economic literature, cost-effectiveness analysis, and budget-impact analysis to ascertain the cost-effectiveness and economic impact of MRD testing by flow cytometry for management of childhood precursor B-cell ALL in Ontario. Methods A systematic literature search (1998–2014) identified studies that examined the incremental cost-effectiveness of MRD testing by either flow cytometry or PCR. We developed a lifetime state-transition (Markov) microsimulation model to quantify the cost-effectiveness of MRD testing followed by risk-directed therapy to no MRD testing and to estimate its marginal effect on health outcomes and on costs. Model input parameters were based on the literature, expert opinion, and data from the Pediatric Oncology Group of Ontario Networked Information System. Using predictions from our Markov model, we estimated the 1-year cost burden of MRD testing versus no testing and forecasted its economic impact over 3 and 5 years. Results In a base-case cost-effectiveness analysis, compared with no testing, MRD testing by flow cytometry at the end of induction and consolidation was associated with an increased discounted survival of 0.0958 quality-adjusted life-years (QALYs) and increased discounted costs of $4,180, yielding an incremental cost-effectiveness ratio (ICER) of $43,613/QALY gained. After accounting for parameter uncertainty, incremental cost-effectiveness of MRD testing was associated with an ICER of $50,249/QALY gained. In

  16. Lipidome and metabolome analysis of fresh tobacco leaves in different geographical regions using liquid chromatography-mass spectrometry.

    Science.gov (United States)

    Li, Lili; Lu, Xin; Zhao, Jieyu; Zhang, Junjie; Zhao, Yanni; Zhao, Chunxia; Xu, Guowang

    2015-07-01

    The combination of the lipidome and the metabolome can provide much more information in plant metabolomics studies. A method for the simultaneous extraction of the lipidome and the metabolome of fresh tobacco leaves was developed. Method validation was performed on the basis of the optimal ratio of methanol to methyl tert-butyl ether to water (37:45:68) from the design of experiments. Good repeatability was obtained. We found that 92.2% and 91.6% of the peaks for the lipidome and the metabolome were within a relative standard deviation of 20%, accounting for 94.6% and 94.6% of the total abundance, respectively. The intraday and interday precisions were also satisfactory. A total of 230 metabolites, including 129 lipids, were identified. Significant differences were found in lipidomic and metabolomic profiles of fresh tobacco leaves in different geographical regions. Highly unsaturated galactolipids, phosphatidylethanolamines, predominant phosphatidylcholines, most of the polyphenols, amino acids, and polyamines had a higher content in Yunnan province, and low-unsaturation-degree galactolipids, triacylglycerols, glucosylceramides with trihydroxy long-chain bases, acylated sterol glucosides, and some organic acids were more abundant in Henan province. Correlation analysis between differential metabolites and climatic factors indicated the vital importance of temperature. The fatty acid unsaturation degree of galactolipids could be influenced by temperature. Accumulation of polyphenols and decreases in the ratios of stigmasterols to sitosterols and glucosylstigmasterols to glucosylsitosterols were also correlated with lower temperature in Yunnan province. Furthermore, lipids were more sensitive to climatic variations than other metabolites.

  17. Spatial Analysis of Severe Fever with Thrombocytopenia Syndrome Virus in China Using a Geographically Weighted Logistic Regression Model

    Directory of Open Access Journals (Sweden)

    Liang Wu

    2016-11-01

    Full Text Available Severe fever with thrombocytopenia syndrome (SFTS is caused by severe fever with thrombocytopenia syndrome virus (SFTSV, which has had a serious impact on public health in parts of Asia. There is no specific antiviral drug or vaccine for SFTSV and, therefore, it is important to determine the factors that influence the occurrence of SFTSV infections. This study aimed to explore the spatial associations between SFTSV infections and several potential determinants, and to predict the high-risk areas in mainland China. The analysis was carried out at the level of provinces in mainland China. The potential explanatory variables that were investigated consisted of meteorological factors (average temperature, average monthly precipitation and average relative humidity, the average proportion of rural population and the average proportion of primary industries over three years (2010–2012. We constructed a geographically weighted logistic regression (GWLR model in order to explore the associations between the selected variables and confirmed cases of SFTSV. The study showed that: (1 meteorological factors have a strong influence on the SFTSV cover; (2 a GWLR model is suitable for exploring SFTSV cover in mainland China; (3 our findings can be used for predicting high-risk areas and highlighting when meteorological factors pose a risk in order to aid in the implementation of public health strategies.

  18. An Indicator of Solid Waste Generation Potential for Illinois Using Principal Components Analysis and Geographic Information Systems.

    Science.gov (United States)

    Dallas, M D; Kerzee, R G; Bing-Canar, J; Mensah, E K; Oroke, K G; Swager, R R

    1996-05-01

    An indicator of solid waste generation potential (SWGP) is proposed as a versatile means to assist the development of integrated solid waste (SW) management plans. The proposed indicator is based on key sodoeconomic variables for the State of Illinois which were found to be highly correlated with variables describing the SW stream of the State. The proposed indicator was derived by applying the principal components analysis (PCA) technique. The technique is used to merge the rank transformed socioeconomic variables into a single variable, the SWGP indicator, while maintaining the regional information of the original variables. An innovative aspect of this indicator approach is the use of the ordinal scale for all these diverse variables. The validity of this approach was assessed and the proposed indicator was found to be directly proportional to a composite variable describing the SW stream for the State of Illinois. The use of Geographic Information Systems (GIS) to depict the spatial distribution of the SWGP will help planners visualize the expected overall refuse generation pattern and to identify critical regions. In addition, the proposed indicator could be used as an instrument to validate the solid waste generation (SWG) quantities reported by counties to state agencies.

  19. A Python-Based Open Source System for Geographic Object-Based Image Analysis (GEOBIA Utilizing Raster Attribute Tables

    Directory of Open Access Journals (Sweden)

    Daniel Clewley

    2014-06-01

    Full Text Available A modular system for performing Geographic Object-Based Image Analysis (GEOBIA, using entirely open source (General Public License compatible software, is presented based around representing objects as raster clumps and storing attributes as a raster attribute table (RAT. The system utilizes a number of libraries, developed by the authors: The Remote Sensing and GIS Library (RSGISLib, the Raster I/O Simplification (RIOS Python Library, the KEA image format and TuiView image viewer. All libraries are accessed through Python, providing a common interface on which to build processing chains. Three examples are presented, to demonstrate the capabilities of the system: (1 classification of mangrove extent and change in French Guiana; (2 a generic scheme for the classification of the UN-FAO land cover classification system (LCCS and their subsequent translation to habitat categories; and (3 a national-scale segmentation for Australia. The system presented provides similar functionality to existing GEOBIA packages, but is more flexible, due to its modular environment, capable of handling complex classification processes and applying them to larger datasets.

  20. Using risk-based analysis and geographic information systems to assess flooding problems in an urban watershed in Rhode Island.

    Science.gov (United States)

    Hardmeyer, Kent; Spencer, Michael A

    2007-04-01

    This article provides an overview of the use of risk-based analysis (RBA) in flood damage assessment, and it illustrates the use of Geographic Information Systems (GIS) in identifying flood-prone areas, which can aid in flood-mitigation planning assistance. We use RBA to calculate expected annual flood damages in an urban watershed in the state of Rhode Island, USA. The method accounts for the uncertainty in the three primary relationships used in computing flood damage: (1) the probability that a given flood will produce a given amount of floodwater, (2) the probability that a given amount of floodwater will reach a certain stage or height, and (3) the probability that a certain stage of floodwater will produce a given amount of damage. A greater than 50% increase in expected annual flood damage is estimated for the future if previous development patterns continue and flood-mitigation measures are not taken. GIS is then used to create a map that shows where and how often floods might occur in the future, which can help (1) identify priority areas for flood-mitigation planning assistance and (2) disseminate information to public officials and other decision-makers.

  1. Water quality analysis of the commercial boreholes in Mubi Metropolis, Adamawa State, Nigeria: geographic information system approach.

    Science.gov (United States)

    Mayomi, Ikusemoran; Elisha, Ibrahim

    2011-12-01

    It is observed that most of the commercial boreholes in Mubi Metropolis are located along River Yedzeram which is the main river that runs across the town. Unfortunately, due to the geographical location of the town in savanna region with minimal water supply, water related small scale industries such as sachet water, block making, irrigation agriculture, cloth dying, car wash and other pollution activities such as mechanical workshops and public toilets are also located along the same River Yedzeram. Moreover, the inhabitants of the town either dump their refuse in the River or spread it on their farmlands as there is no provision of refuse dump site by the government. Therefore, five parameters (Nitrate, Magnesium, Copper, Calcium and Iron) were used to test thewater quality of water samples that were collected from twenty two commercial boreholes along the river, using the standard examination of water and waste water of the World Health Organization to determine the water quality of the boreholes. The study revealed that only eight out of the twenty two boreholes are of good quality, while the others are either of bad quality or not portable. ArcGIS 9.2 and ILWIS 3.3 software were used to analyze the laboratory results through the use of SQL queries. It was recommended that the government should provide portable water, establish water quality control board and make use of GIS for creation of database and analysis.

  2. Clinical and genetic analysis in alternating hemiplegia of childhood: ten new patients from Southern Europe.

    Science.gov (United States)

    Vila-Pueyo, Marta; Pons, Roser; Raspall-Chaure, Miquel; Marcé-Grau, Anna; Carreño, Oriel; Sintas, Cèlia; Cormand, Bru; Pineda-Marfà, Mercè; Macaya, Alfons

    2014-09-15

    Alternating hemiplegia of childhood (AHC) is a rare neurodevelopmental disorder featuring attacks of hemiplegia and other paroxysmal and non-paroxysmal manifestations leading to progressive neurological impairment. De novo mutations in ATP1A3 have been identified in up to 80% of patients. AHC is also associated with rare mutations in other genes involved in episodic neurological disorders. We sought to find mutations in ATP1A3, CACNA1A, ATP1A2, SCN1A and SLC2A1 in a cohort of ten unrelated patients from Spain and Greece. All patients fulfilled AHC diagnostic criteria. All five genes were amplified by PCR and Sanger sequenced. Copy number variation (CNV) analysis of SLC2A1 and CACNA1A was performed using two different approaches. We identified three previously described heterozygous missense ATP1A3 mutations (p.Asp801Asn, p.Glu815Lys and p.Gly947Arg) in five patients. No disease-causing mutations were found in the remaining genes. All mutations occurred de novo; carriers presented on average earlier than non-carriers. Intellectual disability was more severe with the p.Glu815Lys variant. A p.Gly947Arg carrier harbored a maternally-inherited CACNA1A p.Ala454Thr variant. Of note, three of our patients exhibited remarkable clinical responses to the ketogenic diet. We confirmed ATP1A3 mutations in half of our patients. Further AHC genetic studies will need to investigate large rearrangements in ATP1A3 or consider greater genetic heterogeneity than previously suspected.

  3. Geographical information system (GIS) as a new tool to evaluate epidemiology based on spatial analysis and clinical outcomes in acromegaly

    OpenAIRE

    Naves, Luciana Ansaneli; Porto, Lara Benigno; Rosa, João Willy Corrêa; Casulari, Luiz Augusto; Rosa, José Wilson Corrêa

    2013-01-01

    Geographical information systems (GIS) have emerged as a group of innovative software components useful for projects in epidemiology and planning in Health Care System. This is an original study to investigate environmental and geographical influences on epidemiology of acromegaly in Brazil. We aimed to validate a method to link an acromegaly registry with a GIS mapping program, to describe the spatial distribution of patients, to identify disease clusters and to evaluate if the access to Hea...

  4. Flood Vulnerability Analysis of the part of Karad Region, Satara District, Maharashtra using Remote Sensing and Geographic Information System technique

    Science.gov (United States)

    Warghat, Sumedh R.; Das, Sandipan; Doad, Atul; Mali, Sagar; Moon, Vishal S.

    2012-07-01

    Karad City is situated on the bank of confluence of river Krishna & Koyana, which is severely flood prone area. The floodwaters enter the city through the roads and disrupt the infrastructure in the whole city. Furthermore, due to negligence of the authorities and unplanned growth of the city, the people living in the city have harnessed the natural flow of water by constructing unnecessary embankments in the river Koyna. Due to this reason now river koyna is flowing in the form of a narrow channel, which very easily over-flows during very minor flooding.Flood Vulnerabilty Analysis has been done for the karad region of satara district, maharashtra using remote sensing and geographic information system technique. The aim of this study is to identify flood vulnerability zone by using GIS and RS technique and an attempt has been to demonstrat the application of remote sensing and GIS in order to map flood vulnerabilty area by utilizing ArcMap, and Erdas software. Flood vulnerabilty analysis of part the Karad Regian of Satara District, Maharashtra has been carried out with the objectives - Identify the Flood Prone area in the Koyana and Krishna river basin, Calculate surface runoff and Delineate flood sensitive areas. Delineate classified hazard Map, Evaluate the Flood affected area, Prepare the Flood Vulnerability Map by utilizing Remote Sensing and GIS technique. (C.J. Kumanan;S.M. Ramasamy)The study is based on GIS and spatial technique is used for analysis and understanding of flood problem in Karad Tahsil. The flood affected areas of the different magnitude has been identified and mapped using Arc GIS software. The analysis is useful for local planning authority for identification of risk areas and taking proper decision in right moment. In the analysis causative factors for flooding in watershed are taken into account as annual rainfall, size of watershed, basin slope, drainage density of natural channels and land use. (Dinand Alkema; Farah Aziz.)This study of

  5. Causes of accidental childhood deaths in China in 2010: A systematic review and analysis

    Directory of Open Access Journals (Sweden)

    Kit Yee Chan

    2015-06-01

    Full Text Available Background Infectious causes of childhood deaths in the world have decreased substantially in the 21st century. This trend has exposed accidental deaths as an increasingly important future challenge. Presently, little is known about the cause structure of accidental childhood deaths in low– and middle–income country (LMIC settings In this paper, we aim to establish cause structure for accidental deaths in children aged 0–4 years in China in the year 2010. Methods In this paper, we explored the database of 208 multi–cause child mortality studies in Chinese that formed a basis for the first published estimate of the causes of child deaths in China (for the year 2008. Only five of those studies identified specific causes of accidental deaths. Because of this, we searched the Chinese medical literature databases CNKI and WanFang for single–cause mortality studies that were focused on accidental deaths. We identified 71 further studies that provided specific causes for accidental deaths. We used epidemiological modeling to estimate the number of accidental child deaths in China in 2010 and to assign those deaths to specific causes. Results In 2010, we estimated 314 581 deaths in children 0–4 years in China, of which 31 633 (10.1% were accidental. Accidental deaths contributed 7240 (4.0% of all deaths in neonatal period, 8838 (10.5% among all post–neonatal infant deaths, and 15 554 (31.7% among children with 1–4 years of age. Among four tested models, the most predictive was used to establish the likely cause structure of accidental deaths in China. We estimated that asphyxia caused 9490 (95% confidence interval (CI 8224–11 072, drowning 5694 (95% CI 5061–6327, traffic accidents 3796 (95% CI3163–4745, poisoning 3163 (95% CI 2531–3796 and falls 2531 (95% CI 2214–3163 deaths. Based on medians from a few rare studies, we also predict 633 (95% CI 316–1265 deaths to be due to burns and 316 (95% CI 0–633 due to falling objects

  6. An Analysis of the Theoretical Foundations for the Use of Microcomputers in Early Childhood Education.

    Science.gov (United States)

    Streibel, Michael J.

    This discussion first analyzes major claims of a cognitive-developmentalist perspective on the use of microcomputers in early childhood education. Five topics are specifically addressed: microcomputers and intellectual structures, microcomputers as cultural events, microcomputers and strategy repetoires, instruction and the self-construction of…

  7. Clinical presentation of childhood leukaemia : a systematic review and meta-analysis

    NARCIS (Netherlands)

    Clarke, Rachel T; Van den Bruel, Ann; Bankhead, Clare; Mitchell, Christopher D; Phillips, Bob; Thompson, Matthew J

    2016-01-01

    OBJECTIVE: Leukaemia is the most common cancer of childhood, accounting for a third of cases. In order to assist clinicians in its early detection, we systematically reviewed all existing data on its clinical presentation and estimated the frequency of signs and symptoms presenting at or prior to di

  8. Linkage and association analysis of CACNG3 in childhood absence epilepsy

    DEFF Research Database (Denmark)

    Everett, Kate V; Chioza, Barry; Aicardi, Jean;

    2007-01-01

    Childhood absence epilepsy (CAE) is an idiopathic generalised epilepsy characterised by absence seizures manifested by transitory loss of awareness with 2.5-4 Hz spike-wave complexes on ictal EEG. A genetic component to aetiology is established but the mechanism of inheritance and the genes...

  9. Geographical characterization of greek virgin olive oils (cv. Koroneiki) using 1H and 31P NMR fingerprinting with canonical discriminant analysis and classification binary trees.

    Science.gov (United States)

    Petrakis, Panos V; Agiomyrgianaki, Alexia; Christophoridou, Stella; Spyros, Apostolos; Dais, Photis

    2008-05-14

    This work deals with the prediction of the geographical origin of monovarietal virgin olive oil (cv. Koroneiki) samples from three regions of southern Greece, namely, Peloponnesus, Crete, and Zakynthos, and collected in five harvesting years (2001-2006). All samples were chemically analyzed by means of 1H and 31P NMR spectroscopy and characterized according to their content in fatty acids, phenolics, diacylglycerols, total free sterols, free acidity, and iodine number. Biostatistical analysis showed that the fruiting pattern of the olive tree complicates the geographical separation of oil samples and the selection of significant chemical compounds. In this way the inclusion of the harvesting year improved the classification of samples, but increased the dimensionality of the data. Discriminant analysis showed that the geographical prediction at the level of three regions is very high (87%) and becomes (74%) when we pass to the thinner level of six sites (Chania, Sitia, and Heraklion in Crete; Lakonia and Messinia in Peloponnesus; Zakynthos). The use of classification and binary trees made possible the construction of a geographical prediction algorithm for unknown samples in a self-improvement fashion, which can be readily extended to other varieties and areas.

  10. Genetic variability among Hymenolepis nana isolates from different geographical regions in China revealed by sequence analysis of three mitochondrial genes.

    Science.gov (United States)

    Cheng, Tian; Gao, De-Zhen; Zhu, Wei-Ning; Fang, Su-Fang; Chen, Ning; Zhu, Xing-Quan; Liu, Guo-Hua; Lin, Rui-Qing

    2016-11-01

    Hymenolepis nana is a common tapeworm that parasitizes in the small intestine of rodent animals and humans. The present study examined the sequence diversity of three mitochondrial (mt) genes namely NADH dehydrogenase subunits 5 (nad5), small subunit ribosomal RNA (rrnS), and ATPase subunit 6 (atp6) of H. nana from mice in different geographical regions of China. A part of the nad5 (pnad5), complete rrnS and atp6 genes were amplified separately from individual H. nana isolates using polymerase chain reaction (PCR) and then sequenced. The sequences of pnad5, rrnS, and atp6 were 710 bp, 704-711 bp, and 516 bp in length, respectively. The A + T contents of the sequences were 70.1-73.5% (pnad5), 70.1-71.7% (rrnS), and 76.6-77.9% (atp6). Sequence variation within H. nana was 0-1.4% for atp6, 0-1.7% for rrnS, and 0-0.7% for pnad5. The inter-specific sequence differences between H. nana and Hymenolepis diminuta were significantly higher, which was 31.6-31.7% (pnad5), 16.1-17.6% (rrnS), and 26.5-27.1% (atp6). Phylogenetic analysis based on the combined three sequences using the maximum parsimony (MP) method supported that H. nana is a species complex or "cryptic" species. These findings demonstrated clearly the usefulness of the three mtDNA sequences for population genetics and systematic studies of H. nana of human and animal health significance.

  11. Preterm birth and childhood wheezing disorders: a systematic review and meta-analysis.

    Directory of Open Access Journals (Sweden)

    Jasper V Been

    2014-01-01

    Full Text Available BACKGROUND: Accumulating evidence implicates early life factors in the aetiology of non-communicable diseases, including asthma/wheezing disorders. We undertook a systematic review investigating risks of asthma/wheezing disorders in children born preterm, including the increasing numbers who, as a result of advances in neonatal care, now survive very preterm birth. METHODS AND FINDINGS: Two reviewers independently searched seven online databases for contemporaneous (1 January 1995-23 September 2013 epidemiological studies investigating the association between preterm birth and asthma/wheezing disorders. Additional studies were identified through reference and citation searches, and contacting international experts. Quality appraisal was undertaken using the Effective Public Health Practice Project instrument. We pooled unadjusted and adjusted effect estimates using random-effects meta-analysis, investigated "dose-response" associations, and undertook subgroup, sensitivity, and meta-regression analyses to assess the robustness of associations. We identified 42 eligible studies from six continents. Twelve were excluded for population overlap, leaving 30 unique studies involving 1,543,639 children. Preterm birth was associated with an increased risk of wheezing disorders in unadjusted (13.7% versus 8.3%; odds ratio [OR] 1.71, 95% CI 1.57-1.87; 26 studies including 1,500,916 children and adjusted analyses (OR 1.46, 95% CI 1.29-1.65; 17 studies including 874,710 children. The risk was particularly high among children born very preterm (<32 wk gestation; unadjusted: OR 3.00, 95% CI 2.61-3.44; adjusted: OR 2.81, 95% CI 2.55-3.12. Findings were most pronounced for studies with low risk of bias and were consistent across sensitivity analyses. The estimated population-attributable risk of preterm birth for childhood wheezing disorders was ≥3.1%. Key limitations related to the paucity of data from low- and middle-income countries, and risk of residual

  12. Expression analysis of CD63 in salivary neutrophils and the increased level of Streptococcus mutans in severe early childhood caries

    Directory of Open Access Journals (Sweden)

    Muhammad Luthfi

    2015-06-01

    Full Text Available Background: Severe early childhood caries (S-ECC and decay exfoliation filling teeth (def-t >6 is a destructive disease that afflicts teeth, including maxillary anterior teeth. In Indonesia, the prevalence of this disease is still high, for instance in Semarang 2007, the rate reached 90.5% in urban areas and 95.9% in rural areas for early childhood caries which is caused by Streptococcus mutans (S. mutans. Neutrophils are effector cells of innate immunity which become the main component of the very first line of defense against microbes. Purpose: This study analyzed the effect caused by the change of CD63 expression on the surface of salivary neutrophils and the increased level of S. mutans in S-ECC. Method: This study employs observational analytic and cross sectional approach by using T test analysis technique for forty cases of early childhood that had been divided into two groups, first group of twenty children positively diagnosed as S-ECC and second group of twenty children negatively diagnosed as the control group. The sample’s result of gargling with 1.5% NaCl was used for neutrophils isolation and analysis function of salivary neutrophils phagocytosis by using flow cytometry test, while the sample of saliva was used to isolate S. mutans and calculate the level of S. mutans. Result: The expression of CD63+ salivary neutrophils in S-ECC was lower (2.32% ± 0.57 than in caries-free (2.67% ± 0.46, while the level of S. mutans showed that the level was not higher than in S-ECC (9.78 ± 2.22x105 CFU/ml compared to in caries-free (5.13 ± 1.86x105 CFU/ml. Conclusion: The low expression of CD63 in salivary neutrophils can lead to the increased level of S. mutans in S-ECC.

  13. Geographic differences in genetic susceptibility to IgA nephropathy: GWAS replication study and geospatial risk analysis.

    Directory of Open Access Journals (Sweden)

    Krzysztof Kiryluk

    Full Text Available IgA nephropathy (IgAN, major cause of kidney failure worldwide, is common in Asians, moderately prevalent in Europeans, and rare in Africans. It is not known if these differences represent variation in genes, environment, or ascertainment. In a recent GWAS, we localized five IgAN susceptibility loci on Chr.6p21 (HLA-DQB1/DRB1, PSMB9/TAP1, and DPA1/DPB2 loci, Chr.1q32 (CFHR3/R1 locus, and Chr.22q12 (HORMAD2 locus. These IgAN loci are associated with risk of other immune-mediated disorders such as type I diabetes, multiple sclerosis, or inflammatory bowel disease. We tested association of these loci in eight new independent cohorts of Asian, European, and African-American ancestry (N = 4,789, followed by meta-analysis with risk-score modeling in 12 cohorts (N = 10,755 and geospatial analysis in 85 world populations. Four susceptibility loci robustly replicated and all five loci were genome-wide significant in the combined cohort (P = 5×10⁻³²-3×10⁻¹⁰, with heterogeneity detected only at the PSMB9/TAP1 locus (I² = 0.60. Conditional analyses identified two new independent risk alleles within the HLA-DQB1/DRB1 locus, defining multiple risk and protective haplotypes within this interval. We also detected a significant genetic interaction, whereby the odds ratio for the HORMAD2 protective allele was reversed in homozygotes for a CFHR3/R1 deletion (P = 2.5×10⁻⁴. A seven-SNP genetic risk score, which explained 4.7% of overall IgAN risk, increased sharply with Eastward and Northward distance from Africa (r = 0.30, P = 3×10⁻¹²⁸. This model paralleled the known East-West gradient in disease risk. Moreover, the prediction of a South-North axis was confirmed by registry data showing that the prevalence of IgAN-attributable kidney failure is increased in Northern Europe, similar to multiple sclerosis and type I diabetes. Variation at IgAN susceptibility loci correlates with differences in disease prevalence

  14. Geographical identification of saffron (Crocus sativus L.) by linear discriminant analysis applied to the UV-visible spectra of aqueous extracts.

    Science.gov (United States)

    D'Archivio, Angelo Antonio; Maggi, Maria Anna

    2017-03-15

    We attempted geographical classification of saffron using UV-visible spectroscopy, conventionally adopted for quality grading according to the ISO Normative 3632. We investigated 81 saffron samples produced in L'Aquila, Città della Pieve, Cascia, and Sardinia (Italy) and commercial products purchased in various supermarkets. Exploratory principal component analysis applied to the UV-vis spectra of saffron aqueous extracts revealed a clear differentiation of the samples belonging to different quality categories, but a poor separation according to the geographical origin of the spices. On the other hand, linear discriminant analysis based on 8 selected absorbance values, concentrated near 279, 305 and 328nm, allowed a good distinction of the spices coming from different sites. Under severe validation conditions (30% and 50% of saffron samples in the evaluation set), correct predictions were 85 and 83%, respectively.

  15. Does childhood bullying predict eating disorder symptoms? A prospective, longitudinal analysis

    OpenAIRE

    Copeland, William E.; Bulik, Cynthia M.; Zucker, Nancy; Wolke, Dieter; Lereya, Suzet Tanya; Costello, Elizabeth Jane

    2015-01-01

    Objective:\\ud Bullying is a common childhood experience with enduring psychosocial consequences. The aim of this study was to test whether bullying increases risk for eating disorder symptoms.\\ud \\ud Method:\\ud Ten waves of data on 1,420 participants between ages 9 and 25 were used from the prospective population-based Great Smoky Mountains Study. Structured interviews were used to assess bullying involvement and symptoms of anorexia nervosa and bulimia nervosa as well as associated features....

  16. What Will I Be When I Grow Up? An Analysis of Childhood Expectations and Career Outcomes

    OpenAIRE

    Sarah Brown; John Sessions; Karl Taylor

    2004-01-01

    In this paper we utilise the British National Child Development Study to explore the determinants of children’s career expectations formed at the age of sixteen. We analyse how such career expectations impact upon human capital accumulation at the same age. We also analyse the extent of any divergence between childhood career expectations and the actual career outcomes experienced by the individuals at three distinct ages in adulthood (23, 33 and 42) as well as the impact of any such divergen...

  17. Long-Term Neuropsychological Outcomes of Childhood Onset Acute Disseminated Encephalomyelitis (ADEM): a Meta-Analysis.

    Science.gov (United States)

    Burton, Karen L O; Williams, Tracey A; Catchpoole, Sarah E; Brunsdon, Ruth K

    2017-03-31

    The long-term neurocognitive prognosis of childhood onset acute disseminated encephalomyelitis (ADEM) is unclear. This review and quantitative synthesis of the available literature examined whether there are long-term impacts of childhood ADEM on neurocognitive functioning. A search of online databases (MEDLINE, EMBASE, EBSCO CINAHL, PsycINFO and the Cochrane Database of Systematic Reviews) from their inception to October 2015 and reference lists identified 13 papers eligible for inclusion in the systematic review; seven of these were eligible for inclusion in meta-analyses. The systematic review indicated that, at a group level there is a positive long-term neuropsychological outcome from childhood onset ADEM. However, despite the apparent absence of long-term negative impacts of ADEM at a group level, at an individual level impairments in the areas of IQ, attention, executive functioning, processing speed, learning and memory, visuospatial skills and internalising symptoms were found in up to 43% of patients when aggregated across the studies. No significant negative effect of ADEM for any of the neuropsychological domains examined was found in meta-analyses. However, the effects for Processing Speed (r mean = -0.296 (CI 95% = -0.605-0.013)) and Internalising symptoms (r mean = 0.242 (CI 95% = -0.014-0.564)) approached significance (p = 0.06), suggesting a trend towards ADEM leading to long-term reduced processing speed and elevated internalising symptoms. Together, our findings suggest that despite a generally positive neurocognitive outcome post childhood ADEM there are a subset of individuals who can suffer from ongoing specific cognitive impairments. Clinical implications and research priorities are discussed.

  18. Birth Weight and Acute Childhood Leukemia: A Meta-analysis of Observational Studies

    Science.gov (United States)

    2007-11-02

    neurofibromatosis, Shwachman syndrome, Bloom syndrome, ataxia telangiectasia, Langerhans cell histiocytosis, and Klinefelter syndrome Increased...childhood leukemia (both ALL and AML) with maternal history of fetal loss14-16 while one study reported an inverse association.17 Some studies showed...about 1.5 times).124 There is little current insight into the natural history of acute leukemia in children and the likely timing of key

  19. Is childhood bullying involvement a precursor of eating disorder symptoms? A prospective analysis

    Science.gov (United States)

    Copeland, William E.; Bulik, Cynthia M.; Zucker, Nancy; Wolke, Dieter; Lereya, Suzet Tanya; Costello, E. Jane

    2015-01-01

    Objective Bullying is a common childhood experience with enduring psychosocial consequences. The aim of this study was to test whether bullying increases risk for eating disorder symptoms. Method Ten waves of data on 1420 participants between ages 9 and 25 were used from the prospective population-based Great Smoky Mountains Study. Structured interviews were used to assess bullying involvement and symptoms of anorexia nervosa and bulimia nervosa as well as associated features. Bullying involvement was categorized as not involved, bully only, victim only, or both bully and victim (bully-victims). Results Within childhood/adolescence, victims of bullying were at increased risk for symptoms of anorexia nervosa and bulimia nervosa as well as associated features. These associations persisted after accounting for prior eating disorder symptom status as well as preexisting psychiatric status and family adversities. Bullies were at increased risk of symptoms of bulimia and associated features of eating disorders, and bully-victims had higher levels of anorexia symptoms. In terms of individual items, victims were at risk for binge eating and bully-victims had more binge eating and use of vomiting as a compensatory behavior. There was little evidence in this sample that these effects differed by sex. Childhood bullying status was not associated with increased risk for persistent eating disorder symptoms into adulthood (ages 19, 21, and 25). Discussion Bullying predicts eating disorder symptoms for both bullies and victims. Bullying involvement should be a part of risk assessment and treatment planning for children with eating problems. PMID:26337405

  20. Authentication of geographical origin of palm oil by chromatographic fingerprinting of triacylglycerols an partial least square-discriminant analysis

    NARCIS (Netherlands)

    Ruiz-Samblas, C.; Arrebola-Pascual, C.; Tres, A.; Ruth, van S.M.; Cuadros-Rodriquez, L.

    2013-01-01

    Main goals of the present work were to develop authentication models based on liquid and gas chromatographic fingerprinting of triacylglycerols (TAGs) from palm oil of different geographical origins in order to compare them. For this purpose, a set of palm oil samples were collected from different c

  1. Full length genome analysis of Vesicular Stomatitis New Jersey Virus strains representing the phylogenetic and geographic diversity of the virus

    Science.gov (United States)

    We describe the complete genomic sequence of nine isolates of Vesicular Stomatitis New Jersey virus (VSNJV) representing six distinct phylogenetic groups and spanning the known geographic range of the virus. The total genomic length (11119-11123nt) and structure of these isolates were very similar ...

  2. Mutual misunderstanding and avoidance, misrepresentations and disciplinary politics: spatial science and quantitative analysis in (United Kingdom) geographical curricula

    DEFF Research Database (Denmark)

    Johnston, Ron; Harris, Richard J; Jones, Kelvyn

    2014-01-01

    One consequence of the fragmentation of their discipline and the consequent lack of awareness amongst human geographers of what is being done by many of their colleagues is misrepresentation of certain types of work ? in textbooks, for example. Amongst the areas often misrepresented in recent years...

  3. Geographical networks: geographical effects on network properties

    Institute of Scientific and Technical Information of China (English)

    Kong-qing YANG; Lei YANG; Bai-hua GONG; Zhong-cai LIN; Hong-sheng HE; Liang HUANG

    2008-01-01

    Complex networks describe a wide range of sys-tems in nature and society. Since most real systems exist in certain physical space and the distance between the nodes has influence on the connections, it is helpful to study geographi-cal complex networks and to investigate how the geographical constrains on the connections affect the network properties. In this paper, we briefly review our recent progress on geo-graphical complex networks with respect of statistics, mod-elling, robustness, and synchronizability. It has been shown that the geographical constrains tend to make the network less robust and less synchronizable. Synchronization on random networks and clustered networks is also studied.

  4. Spatial Point Pattern Analysis of Human Settlements and Geographical Associations in Eastern Coastal China — A Case Study

    Directory of Open Access Journals (Sweden)

    Zhonghao Zhang

    2014-03-01

    Full Text Available Understanding the spatial point pattern of human settlements and their geographical associations are important for understanding the drivers of land use and land cover change and the relationship between environmental and ecological processes on one hand and cultures and lifestyles on the other. In this study, a Geographic Information System (GIS approach, Ripley’s K function and Monte Carlo simulation were used to investigate human settlement point patterns. Remotely sensed tools and regression models were employed to identify the effects of geographical determinants on settlement locations in the Wen-Tai region of eastern coastal China. Results indicated that human settlements displayed regular-random-cluster patterns from small to big scale. Most settlements located on the coastal plain presented either regular or random patterns, while those in hilly areas exhibited a clustered pattern. Moreover, clustered settlements were preferentially located at higher elevations with steeper slopes and south facing aspects than random or regular settlements. Regression showed that influences of topographic factors (elevation, slope and aspect on settlement locations were stronger across hilly regions. This study demonstrated a new approach to analyzing the spatial patterns of human settlements from a wide geographical prospective. We argue that the spatial point patterns of settlements, in addition to the characteristics of human settlements, such as area, density and shape, should be taken into consideration in the future, and land planners and decision makers should pay more attention to city planning and management. Conceptual and methodological bridges linking settlement patterns to regional and site-specific geographical characteristics will be a key to human settlement studies and planning.

  5. Ultraviolet spectroscopy combined with ultra-fast liquid chromatography and multivariate statistical analysis for quality assessment of wild Wolfiporia extensa from different geographical origins

    Science.gov (United States)

    Li, Yan; Zhang, Ji; Jin, Hang; Liu, Honggao; Wang, Yuanzhong

    2016-08-01

    A quality assessment system comprised of a tandem technique of ultraviolet (UV) spectroscopy and ultra-fast liquid chromatography (UFLC) aided by multivariate analysis was presented for the determination of geographic origin of Wolfiporia extensa collected from five regions in Yunnan Province of China. Characteristic UV spectroscopic fingerprints of samples were determined based on its methanol extract. UFLC was applied for the determination of pachymic acid (a biomarker) presented in individual test samples. The spectrum data matrix and the content of pachymic acid were integrated and analyzed by partial least squares discriminant analysis (PLS-DA) and hierarchical cluster analysis (HCA). The results showed that chemical properties of samples were clearly dominated by the epidermis and inner part as well as geographical origins. The relationships among samples obtained from these five regions have been also presented. Moreover, an interesting finding implied that geographical origins had much greater influence on the chemical properties of epidermis compared with that of the inner part. This study demonstrated that a rapid tool for accurate discrimination of W. extensa by UV spectroscopy and UFLC could be available for quality control of complicated medicinal mushrooms.

  6. Geographical and Ethnic Distributions of the MTHFR C677T, A1298C and MTRR A66G Gene Polymorphisms in Chinese Populations: A Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Xingmin Wang

    Full Text Available The geographical and ethnic distributions of the polymorphic methylenetetrahydrofolate reductase (MTHFR mutations (C677T and A1298C and methionine synthase reductase (MTRR mutation (A66G remain heterogeneous in China. The goal of this study was to estimate the pooled frequencies of the alleles and associated genotypes of these gene polymorphisms among healthy populations in Mainland China.We systematically reviewed published epidemiological studies on the distributions of 3 genetic variants in Chinese healthy populations living in Mainland China through a meta-analysis. The relevant electronic databases were searched. All of the raw data of the eligible citations were extracted. The frequency estimates were stratified by geography, ethnicity and sex.Sixty-six studies were identified with a total of 92277 study participants. The meta-analysis revealed that the frequencies of the MTHFR C677T, A1298C, and MTRR A66G gene polymorphisms varied significantly between different ethnic groups and along geographical gradients. The frequencies of the 677T allele and 677TT genotype increased along the southern-central-northern direction across Mainland China (all Pvalues≤0.001. The frequencies of the 1298C, 1298CC, 66G and 66GG genotypes decreased along the south-central-north direction across the country (all Pvalues≤0.001.Our meta-analysis strongly indicates significant geographical and ethnic variations in the frequencies of the C677T, A1298C, and A66G gene polymorphisms in the folate metabolism pathway among Chinese populations.

  7. Optimal site selection for sitting a solar park using multi-criteria decision analysis and geographical information systems

    Science.gov (United States)

    Georgiou, Andreas; Skarlatos, Dimitrios

    2016-07-01

    Among the renewable power sources, solar power is rapidly becoming popular because it is inexhaustible, clean, and dependable. It has also become more efficient since the power conversion efficiency of photovoltaic solar cells has increased. Following these trends, solar power will become more affordable in years to come and considerable investments are to be expected. Despite the size of solar plants, the sitting procedure is a crucial factor for their efficiency and financial viability. Many aspects influence such a decision: legal, environmental, technical, and financial to name a few. This paper describes a general integrated framework to evaluate land suitability for the optimal placement of photovoltaic solar power plants, which is based on a combination of a geographic information system (GIS), remote sensing techniques, and multi-criteria decision-making methods. An application of the proposed framework for the Limassol district in Cyprus is further illustrated. The combination of a GIS and multi-criteria methods produces an excellent analysis tool that creates an extensive database of spatial and non-spatial data, which will be used to simplify problems as well as solve and promote the use of multiple criteria. A set of environmental, economic, social, and technical constrains, based on recent Cypriot legislation, European's Union policies, and expert advice, identifies the potential sites for solar park installation. The pairwise comparison method in the context of the analytic hierarchy process (AHP) is applied to estimate the criteria weights in order to establish their relative importance in site evaluation. In addition, four different methods to combine information layers and check their sensitivity were used. The first considered all the criteria as being equally important and assigned them equal weight, whereas the others grouped the criteria and graded them according to their objective perceived importance. The overall suitability of the study

  8. Geographic information system for fusion and analysis of high-resolution remote sensing and ground truth data

    Science.gov (United States)

    Freeman, Anthony; Way, Jo Bea; Dubois, Pascale; Leberl, Franz

    1992-01-01

    We seek to combine high-resolution remotely sensed data with models and ground truth measurements, in the context of a Geographical Information System, integrated with specialized image processing software. We will use this integrated system to analyze the data from two Case Studies, one at a bore Al forest site, the other a tropical forest site. We will assess the information content of the different components of the data, determine the optimum data combinations to study biogeophysical changes in the forest, assess the best way to visualize the results, and validate the models for the forest response to different radar wavelengths/polarizations. During the 1990's, unprecedented amounts of high-resolution images from space of the Earth's surface will become available to the applications scientist from the LANDSAT/TM series, European and Japanese ERS-1 satellites, RADARSAT and SIR-C missions. When the Earth Observation Systems (EOS) program is operational, the amount of data available for a particular site can only increase. The interdisciplinary scientist, seeking to use data from various sensors to study his site of interest, may be faced with massive difficulties in manipulating such large data sets, assessing their information content, determining the optimum combinations of data to study a particular parameter, visualizing his results and validating his model of the surface. The techniques to deal with these problems are also needed to support the analysis of data from NASA's current program of Multi-sensor Airborne Campaigns, which will also generate large volumes of data. In the Case Studies outlined in this proposal, we will have somewhat unique data sets. For the Bonanza Creek Experimental Forest (Case I) calibrated DC-8 SAR data and extensive ground truth measurement are already at our disposal. The data set shows documented evidence to temporal change. The Belize Forest Experiment (Case II) will produce calibrated DC-8 SAR and AVIRIS data, together with

  9. Early Childhood Inclusion in Spain

    Science.gov (United States)

    Giné, Climent; Balcells-Balcells, Anna; Cañadas, Margarita; Paniagua, Gema

    2016-01-01

    This article describes early childhood inclusion in educational settings in Spain. First, we address the legislative framework of preschool education in Spain and offer a brief analysis of some relevant issues, including the current situation of early childhood education and inclusion at this stage. Second, current policies and practices relating…

  10. The association between environmental exposures during childhood and the subsequent development of Crohn’s disease: A score analysis approach

    Science.gov (United States)

    Jordaan, Esme; Mazinu, Mikateko

    2017-01-01

    Background Environmental factors during childhood are thought to play a role in the aetiology of Crohn’s Disease (CD). In South Africa, recently published work based on an investigation of 14 childhood environmental exposures during 3 age intervals (0–5, 6–10 and 11–18 years) has provided insight into the role of timing of exposure in the future development of CD. The ‘overlapping’ contribution of the investigated variables however, remains unclear. The aim of this study was to perform a post hoc analysis using this data and investigate the extent to which each variable contributes to the subsequent development of CD relative to each aforementioned age interval, based on a score analysis approach. Methods Three methods were used for the score analysis. Two methods employed the subgrouping of one or more (similar) variables (methods A and B), with each subgroup assigned a score value weighting equal to one. For comparison, the third approach (method 0) involved no grouping of the 14 variables. Thus, each variable held a score value of one. Results Results of the score analysis (Method 0) for the environmental exposures during 3 age intervals (0–5, 6–10 and 11–18 years) revealed no significant difference between the case and control groups. By contrast, results from Method A and Method B revealed a significant difference during all 3 age intervals between the case and control groups, with cases having significantly lower exposure scores (approximately 30% and 40% lower, respectively). Conclusion Results from the score analysis provide insight into the ‘compound’ effects from multiple environmental exposures in the aetiology of CD. PMID:28170439

  11. Childhood Cancer Statistics

    Science.gov (United States)

    ... Room Employment Feedback Contact Select Page Childhood Cancer Statistics Home > Cancer Resources > Childhood Cancer Statistics Childhood Cancer Statistics – Graphs and Infographics Number of Diagnoses Incidence Rates ...

  12. Ring distributions leading to species formation: a global topographic analysis of geographic barriers associated with ring species

    OpenAIRE

    Monahan William B; Pereira Ricardo J; Wake David B

    2012-01-01

    Abstract Background In the mid 20th century, Ernst Mayr and Theodosius Dobzhansky championed the significance of circular overlaps or ring species as the perfect demonstration of speciation, yet in the over 50 years since, only a handful of such taxa are known. We developed a topographic model to evaluate whether the geographic barriers that favor processes leading to ring species are common or rare, and to predict where other candidate ring barriers might be found. Results Of the 952,147 geo...

  13. Research on Geographical Urban Conditions Monitoring

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    by LUO A1inghai Abstract Geographical national conditions monitoring has become an important task of surveying and geographical information industry, and will make a profound influence on the development of surveying and ge- ographical information. This paper introduced the basic concept of ge- ographical national conditions monitoring, and discussed its main tasks including complete surveying, dynamic monitoring, statistical analysis and regular release, and expounded the main content of geographical urban conditions monitoring including urbanization monitoring, social- economic development monitoring, transportation foundation monitor- ing and natural ecological environment monitoring, and put forwards the framework system of geographical urban conditions monitoring. Key words surveying and mapping ,geographical national conditions, monitoring ( Page:l )

  14. The Immunomodulatory Effect of Acupoint Application for Childhood Asthma: A Systematic Review and Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Xiao Cun Yang

    2015-01-01

    Full Text Available Objective. To evaluate the evidence on the immunomodulatory effect of acupoint application for childhood asthma. Methods. Five electronic databases through October 2014 were searched. The risk of bias in eligible studies was assessed using the Cochrane Collaboration tool. Standardised mean difference (SMD and 95% confidence intervals (CI of random-effects model were calculated. And heterogeneity was assessed using the Cochran Q statistic and quantified with the I2 index. Results. Six studies were included in our review. The aggregated results suggested that acupoint application showed the beneficial effect for childhood asthma in improving IgA (SMD, −0.83; 95% CI −1.14 to −0.52; P<0.00001, IgE (SMD, −0.52; 95% CI −0.76 to −0.29; P<0.001, IgG (SMD, −1.17; 95% CI −1.61 to −0.74; P<0.0001, IL-4 (SMD, −0.57; 95% CI −0.91 to −0.23; P=0.0009, and IFN-γ (SMD, −0.38; 95% CI −0.71 to −0.04; P=0.03 but not IgM (SMD, −0.40; 95% CI −0.98 to 0.18; P=0.18. And the effective dose of acupoint application may be 2–6 hours/time and a total of 3 times within 4 weeks. Conclusions. This review showed the positive evidence that acupoint application had the favorable immunomodulatory effect for childhood asthma. However, more studies with long follow-up are warrant to confirm the current findings.

  15. Tagging in Volunteered Geographic Information: An Analysis of Tagging Practices for Cities and Urban Regions in OpenStreetMap

    Directory of Open Access Journals (Sweden)

    Nikola Davidovic

    2016-12-01

    Full Text Available In Volunteered Geographic Information (VGI projects, the tagging or annotation of objects is usually performed in a flexible and non-constrained manner. Contributors to a VGI project are normally free to choose whatever tags they feel are appropriate to annotate or describe a particular geographic object or place. In OpenStreetMap (OSM, the Map Features part of the OSM Wiki serves as the de-facto rulebook or ontology for the annotation of features in OSM. Within Map Features, suggestions and guidance on what combinations of tags to use for certain geographic objects are outlined. In this paper, we consider these suggestions and recommendations and analyse the OSM database for 40 cities around the world to ascertain if contributors to OSM in these urban areas are using this guidance in their tagging practices. Overall, we find that compliance with the suggestions and guidance in Map Features is generally average or poor. This leads us to conclude that contributors in these areas do not always tag features with the same level of annotation. Our paper also confirms anecdotal evidence that OSM Map Features is less influential in how OSM contributors tag objects.

  16. Analysis of Relationships between Altitude and Distance from Volcano with Stomach Cancer Incidence Using a Geographic Information System.

    Science.gov (United States)

    Amani, F; Ahari, S Sadeghieh; Barzegari, S; Hassanlouei, B; Sadrkabir, M; Farzaneh, Esmaeil

    2015-01-01

    Gastric cancer (GC) is the fifth most common cancer in the world, with a wide variation in incidence rates across different geographical areas. In Iran GC is the most common cancer in males and it is reported to be the third most prevalent after breast and colorectal in females. A geographical information system (GIS) allows investigation of the geographical distribution of diseases. The purpose of the present study was to explore the relationship between gastric cancer and effective climatic factors using GIS. The dispersion distribution and the relationship between environmental factors effective on cancer were measured using Arc GIS. Of all cases, 672 (73.8%) were in males with a sex ratio of 3 to 1. The highest incidence by cities was seen in Namin with 137.5 per 100,000. The results of this study showed that the distribution of GC around the Sabalan volcanic mountain was significantly higher than other places in the same province. These results can be considered as a window to future comprehensive research on gastric cancer.

  17. Childhood Emergencies

    Science.gov (United States)

    ... emergency physicians. They receive comprehensive training in treating childhood emergencies and have more training in pediatric emergencies than other physicians, including pediatricians. Does Your Child's School Know About Food Allergies? - 8/10/2015 The nation's emergency physician ...

  18. Childhood Craniopharyngioma

    Science.gov (United States)

    ... has any of the following: Headaches, including morning headache or headache that goes away after vomiting . Vision changes. Nausea ... Cancer Late Effects of Treatment for Childhood Cancer Adolescents and Young Adults with Cancer Children with Cancer: ...

  19. Ring distributions leading to species formation: a global topographic analysis of geographic barriers associated with ring species

    Directory of Open Access Journals (Sweden)

    Monahan William B

    2012-03-01

    Full Text Available Abstract Background In the mid 20th century, Ernst Mayr and Theodosius Dobzhansky championed the significance of circular overlaps or ring species as the perfect demonstration of speciation, yet in the over 50 years since, only a handful of such taxa are known. We developed a topographic model to evaluate whether the geographic barriers that favor processes leading to ring species are common or rare, and to predict where other candidate ring barriers might be found. Results Of the 952,147 geographic barriers identified on the planet, only about 1% are topographically similar to barriers associated with known ring taxa, with most of the likely candidates occurring in under-studied parts of the world (for example, marine environments, tropical latitudes. Predicted barriers separate into two distinct categories: (i single cohesive barriers (2, associated with taxa that differentiate at smaller spatial scales (salamander: Ensatina eschscholtzii; tree: Acacia karroo; and (ii composite barriers - formed by groups of barriers (each 184,000 to 1.7 million km2 in close geographic proximity (totaling 1.9 to 2.3 million km2 - associated with taxa that differentiate at larger spatial scales (birds: Phylloscopus trochiloides and Larus (sp. argentatus and fuscus. When evaluated globally, we find a large number of cohesive barriers that are topographically similar to those associated with known ring taxa. Yet, compared to cohesive barriers, an order of magnitude fewer composite barriers are similar to those that favor ring divergence in species with higher dispersal. Conclusions While these findings confirm that the topographic conditions that favor evolutionary processes leading to ring speciation are, in fact, rare, they also suggest that many understudied natural systems could provide valuable demonstrations of continuous divergence towards the formation of new species. Distinct advantages of the model are that it (i requires no a priori information on the

  20. Childhood chronic inflammatory demyelinating polyradiculoneuropathy: combined analysis of a large cohort and eleven published series.

    Science.gov (United States)

    McMillan, Hugh J; Kang, Peter B; Jones, H Royden; Darras, Basil T

    2013-02-01

    The clinical presentation, disease course, response to treatment, and long-term outcome of thirty childhood chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) patients are presented representing the largest cohort reported to date. Most children (60%) presented with chronic (>8-weeks) symptom-onset while a smaller proportion showed sub-acute (4-8 weeks) or acute (''GBS-like''; CIDP series providing a comprehensive review of 143 childhood CIDP cases. The combined initial or first-line treatment response across all studies was favourable for IVIG (79% patients) and corticosteroids (84% patients). Response to first-line plasma exchange was poor (only 14% patients improved) although it may offer some transient or partial benefit as an adjuvant or temporary therapy for selected patients. The combined long-term outcome of our cohort and the literature reveals a favourable prognosis for most patients. The combined modified Rankin scale decreased from 3.7 (at presentation) to 0.7 (at last follow-up). This review provides important data pertaining to clinical course, treatment response and long-term outcome of this relatively uncommon paediatric autoimmune disease.

  1. Geographic Stereo Video Data Analysis and Model Design%地理立体视频数据分析与模型设计

    Institute of Scientific and Technical Information of China (English)

    韩志刚; 孔云峰; 秦奋; 王万同

    2013-01-01

    针对当前GIS中视频数据管理的功能较单一、检索方法单调的现状,通过分析、整合空间数据、视频数据,设计了一个地理立体视频数据模型(GeoSVDM),它包括视频、空间几何、专题属性、语义标注以及线性参照等要素,基于面向对象方法,抽象了视频帧及其位置、视域、视频片段及其轨迹等组件对象及其逻辑关系,并应用UML定义了模型结构.该模型通过建立视频对象与地理实体间的空间位置参照及语义参照关系,支持可视化、检索以及量测等多个应用功能,实现了地理立体视频对象数据组织与检索表达.试验表明,GeoSVDM具有功能丰富、集成化以及松耦合、灵活可扩展等优点,适合于地理立体视频的管理,并为GIS中应用可定位媒体提供了基础数据模型.%With the rapid advance of the multimedia and position technology,the new-style geo-tagged media,such as geographic video, panoramic picture and measurable image, have been introduced in GIS applications. This paper aims to introduce the stereo video to geographic information science. Geographic stereo video includes both spatial and temporal geographic characteristics acquired through ground-based or non-ground-based cameras. It is the stereo video that extends the elements of interior and exterior orientation for video frame. And it supports the video retrieval and image measurement based on the spatial information. It has been a new way for geographic representation. Regarding to the disadvantage of the existing methods for video management in GIS such as single function and monotone querying methods,a geographic stereo video data model(GeoSVDM)is proposed on the basis of analysis and integration of the spatial and video data. The model was composed of entities of video,geometry, theme, semantic annotation and linear reference. The video frame and its location or field of view, the video segment and its trajectories are abstracted based

  2. Self Reported Childhood Difficulties, Adult Multimorbidity and Allostatic Load. A Cross-Sectional Analysis of the Norwegian HUNT Study.

    Directory of Open Access Journals (Sweden)

    Margret Olafia Tomasdottir

    Full Text Available Multimorbidity receives increasing scientific attention. So does the detrimental health impact of adverse childhood experiences (ACE. Aetiological pathways from ACE to complex disease burdens are under investigation. In this context, the concept of allostatic overload is relevant, denoting the link between chronic detrimental stress, widespread biological perturbations and disease development. This study aimed to explore associations between self-reported childhood quality, biological perturbations and multimorbidity in adulthood.We included 37 612 participants, 30-69 years, from the Nord-Trøndelag Health Study, HUNT3 (2006-8. Twenty one chronic diseases, twelve biological parameters associated with allostatic load and four behavioural factors were analysed. Participants were categorised according to the self-reported quality of their childhood, as reflected in one question, alternatives ranging from 'very good' to 'very difficult'. The association between childhood quality, behavioural patterns, allostatic load and multimorbidity was compared between groups.Overall, 85.4% of participants reported a 'good' or 'very good' childhood; 10.6% average, 3.3% 'difficult' and 0.8% 'very difficult'. Childhood difficulties were reported more often among women, smokers, individuals with sleep problems, less physical activity and lower education. In total, 44.8% of participants with a very good childhood had multimorbidity compared to 77.1% of those with a very difficult childhood (Odds ratio: 5.08; 95% CI: 3.63-7.11. Prevalences of individual diseases also differed significantly according to childhood quality; all but two (cancer and hypertension showed a significantly higher prevalence (p<0.05 as childhood was categorised as more difficult. Eight of the 12 allostatic parameters differed significantly between childhood groups.We found a general, graded association between self-reported childhood difficulties on the one hand and multimorbidity, individual

  3. Parent-completed scales for measuring seizure severity and severity of side-effects of antiepileptic drugs in childhood epilepsy: development and psychometric analysis.

    NARCIS (Netherlands)

    W.F.M. Arts (Willem Frans); J.A. Carpay (Hans); J. Vermeulen (Jan); H. Stroink (Hans); O.F. Brouwer (Oebele); A.C.B. Peters (Boudewijn); C.A. van Donselaar (Cees); A.P. Aldenkamp (Albert)

    1996-01-01

    textabstractWe have developed two outcome measures for childhood epilepsy: a seizure severity (SS) scale and a side-effects (SE) scale. Both scales have been designed for completion by parents. The scales were tested in two pilot phases and the results of this stepwise analysis are described here. T

  4. Geographical information systems

    DEFF Research Database (Denmark)

    Möller, Bernd

    2004-01-01

    The chapter gives an introduction to Geographical Information Systems (GIS) with particular focus on their application within environmental management.......The chapter gives an introduction to Geographical Information Systems (GIS) with particular focus on their application within environmental management....

  5. The National Map - geographic names

    Science.gov (United States)

    Yost, Lou; Carswell, William J.

    2009-01-01

    The Geographic Names Information System (GNIS), developed by the U.S. Geological Survey (USGS) in cooperation with the U.S. Board on Geographic Names (BGN), contains information about the official names for places, features, and areas in the 50 States, the District of Columbia, the territories and outlying areas of the United States, including Antarctica. It is the geographic names component of The National Map. The BGN maintains working relationships with State names authorities to cooperate in achieving the standardization of geographic names. The GNIS contains records on more than 2 million geographic names in the United States - from populated places, schools, reservoirs, and parks to streams, valleys, springs, ridges, and every feature type except roads and highways. Entries include information such as the federally-recognized name and variant names and spellings for the feature; former names; the status of the name as determined by the BGN; county or counties in which each named feature is located; geographic coordinates that locate the approximate center of an aerial feature or the mouth and source of a linear feature, such as a stream; name of the cell of the USGS topographic map or maps on which the feature may appear; elevation figures derived from the National Elevation Dataset; bibliographic code for the source of the name; BGN decision dates and historical information are available for some features. Data from the GNIS are used for emergency preparedness, mapmaking, local and regional planning, service delivery routing, marketing, site selection, environmental analysis, genealogical research, and other applications.

  6. Atmospheric pressure chemical ionisation mass spectrometry analysis linked with chemometrics for food classification - a case study: geographical provenance and cultivar classification of monovarietal clarified apple juices.

    Science.gov (United States)

    Gan, Heng-Hui; Soukoulis, Christos; Fisk, Ian

    2014-03-01

    In the present work, we have evaluated for first time the feasibility of APCI-MS volatile compound fingerprinting in conjunction with chemometrics (PLS-DA) as a new strategy for rapid and non-destructive food classification. For this purpose 202 clarified monovarietal juices extracted from apples differing in their botanical and geographical origin were used for evaluation of the performance of APCI-MS as a classification tool. For an independent test set PLS-DA analyses of pre-treated spectral data gave 100% and 94.2% correct classification rate for the classification by cultivar and geographical origin, respectively. Moreover, PLS-DA analysis of APCI-MS in conjunction with GC-MS data revealed that masses within the spectral ACPI-MS data set were related with parent ions or fragments of alkyesters, carbonyl compounds (hexanal, trans-2-hexenal) and alcohols (1-hexanol, 1-butanol, cis-3-hexenol) and had significant discriminating power both in terms of cultivar and geographical origin.

  7. Geographic Media Literacy

    Science.gov (United States)

    Lukinbeal, Chris

    2014-01-01

    While the use of media permeates geographic research and pedagogic practice, the underlying literacies that link geography and media remain uncharted. This article argues that geographic media literacy incorporates visual literacy, information technology literacy, information literacy, and media literacy. Geographic media literacy is the ability…

  8. Genetic diversity analysis reveals that geographical environment plays a more important role than rice cultivar in Villosiclava virens population selection.

    Science.gov (United States)

    Wang, Fei; Zhang, Shu; Liu, Mei-Gang; Lin, Xian-Song; Liu, Hui-Jiang; Peng, You-Liang; Lin, Yang; Huang, Jun-Bin; Luo, Chao-Xi

    2014-05-01

    Rice false smut caused by Villosiclava virens is an economically important disease of grains worldwide. The genetic diversity of 153 isolates from six fields located in Wuhan (WH), Yichang Wangjia (YCW), Yichang Yaohe (YCY), Huanggang (HG), Yangxin (YX), and Jingzhou (JZ) in Hubei province of China were phylogenetically analyzed to evaluate the influence of environments and rice cultivars on the V. virens populations. Isolates (43) from Wuhan were from two rice cultivars, Wanxian 98 and Huajing 952, while most of the other isolates from fields YCW, YCY, HG, YX, and JZ originated from different rice cultivars with different genetic backgrounds. Genetic diversity of isolates was analyzed using random amplified polymorphic DNA (RAPD) and single-nucleotide polymorphisms (SNP). The isolates from the same cultivars in Wuhan tended to group together, indicating that the cultivars had an important impact on the fungal population. The 110 isolates from individual fields tended to cluster according to geographical origin. The values of Nei's gene diversity (H) and Shannon's information index (I) showed that the genetic diversity among isolates was higher between than within geographical populations. Furthermore, mean genetic distance between groups (0.006) was higher than mean genetic distance within groups (0.0048) according to MEGA 5.2. The pairwise population fixation index (FST) values also showed significant genetic differentiation between most populations. Higher genetic similarity of isolates from individual fields but different rice cultivars suggested that the geographical factor played a more important role in the selection of V. virens isolates than rice cultivars. This information could be used to improve the management strategy for rice false smut by adjusting the cultivation measures, such as controlling fertilizer, water, and planting density, in the rice field to change the microenvironment.

  9. Social and geographical inequalities in suicide in Japan from 1975 through 2005: a census-based longitudinal analysis.

    Directory of Open Access Journals (Sweden)

    Etsuji Suzuki

    Full Text Available BACKGROUND: Despite advances in our understanding of the countercyclical association between economic contraction and suicide, less is known about the levels of and changes in inequalities in suicide. The authors examined social and geographical inequalities in suicide in Japan from 1975 through 2005. METHODS: Based on quinquennial vital statistics and census data, the authors analyzed the entire population aged 25-64 years. The total number of suicides was 75,840 men and 30,487 women. For each sex, the authors estimated odds ratios (ORs and 95% credible intervals (CIs for suicide using multilevel logistic regression models with "cells" (cross-tabulated by age and occupation at level 1, seven different years at level 2, and 47 prefectures at level 3. Prefecture-level variance was used as an estimate of geographical inequalities in suicide. RESULTS: Adjusting for age and time-trends, the lowest odds for suicide was observed among production process and related workers (the reference group in both sexes. The highest OR for men was 2.52 (95% CI: 2.43, 2.61 among service workers, whereas the highest OR for women was 9.24 (95% CI: 7.03, 12.13 among security workers. The degree of occupational inequalities increased among men with a striking change in the pattern. Among women, we observed a steady decline in suicide risk across all occupations, except for administrative and managerial workers and transport and communication workers. After adjusting for individual age, occupation, and time-trends, prefecture-specific ORs ranged from 0.76 (Nara Prefecture to 1.36 (Akita Prefecture for men and from 0.79 (Kanagawa Prefecture to 1.22 (Akita Prefecture for women. Geographical inequalities have increased primarily among men since 1995. CONCLUSIONS: The present findings demonstrate a striking temporal change in the pattern of social inequalities in suicide among men. Further, geographical inequalities in suicide have considerably increased across 47

  10. What influences national and foreign physicians’ geographic distribution? An analysis of medical doctors’ residence location in Portugal

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    Russo Giuliano

    2012-07-01

    Full Text Available Abstract Background The debate over physicians’ geographical distribution has attracted the attention of the economic and public health literature over the last forty years. Nonetheless, it is still to date unclear what influences physicians’ location, and whether foreign physicians contribute to fill the geographical gaps left by national doctors in any given country. The present research sets out to investigate the current distribution of national and international physicians in Portugal, with the objective to understand its determinants and provide an evidence base for policy-makers to identify policies to influence it. Methods A cross-sectional study of physicians currently registered in Portugal was conducted to describe the population and explore the association of physician residence patterns with relevant personal and municipality characteristics. Data from the Portuguese Medical Council on physicians’ residence and characteristics were analysed, as well as data from the National Institute of Statistics on municipalities’ population, living standards and health care network. Descriptive statistics, chi-square tests, negative binomial and logistic regression modelling were applied to determine: (a municipality characteristics predicting Portuguese and International physicians’ geographical distribution, and; (b doctors’ characteristics that could increase the odds of residing outside the country’s metropolitan areas. Results There were 39,473 physicians in Portugal in 2008, 51.1% of whom male, and 40.2% between 41 and 55 years of age. They were predominantly Portuguese (90.5%, with Spanish, Brazilian and African nationalities also represented. Population, Population’s Purchasing Power, Nurses per capita and Municipality Development Index (MDI were the municipality characteristics displaying the strongest association with national physicians’ location. For foreign physicians, the MDI was not statistically significant

  11. Guidelines for maintenance treatment of childhood asthma: development of a score card system by multivariate cluster analysis.

    Science.gov (United States)

    Donnelly, W J; Donnelly, J E; Thong, Y H

    1987-01-01

    Multivariate cluster analysis of data on 128 asthmatic children resulted in the identification of 8 major discriminating variables. Stepwise divisions by this computer programme resulted in the formation of 6 grades of severity. There was significant correlation between higher grades of severity and early onset of the disease (P less than 0.02). There was also significant correlation between higher grades of severity and greater use of interval medications (P less than 0.002). However, 27.3% were receiving inadequate interval medications in respect of their grade of severity. Assignation of a 5-point scale to each of the 8 major discriminating variables resulted in the generation of computer-designated scores commensurate with each grade of severity. This was coupled to current recommendations for stepwise maintenance medications appropriate for each grade. This Score Card system for maintenance management of childhood asthma may prove useful in busy clinical settings.

  12. The Recalled Childhood Gender Questionnaire-Revised: a psychometric analysis in a sample of women with congenital adrenal hyperplasia.

    Science.gov (United States)

    Meyer-Bahlburg, Heino F L; Dolezal, Curtis; Zucker, Kenneth J; Kessler, Suzanna J; Schober, Justine M; New, Maria I

    2006-11-01

    We administered the 18-item Recalled Childhood Gender Questionnaire-Revised (RCGQ-R), female version, to 147 adult women with congenital adrenal hyperplasia (CAH) representing three different degrees of prenatal androgenization due to 21-hydroxylase deficiency and to non-CAH controls. A principal components analysis generated three components accounting for 46%, 9%, and 6% of the variance, respectively. Corresponding unit-weighted scales (high scores = feminine) were labeled Gender Role (13 items; Cronbach alpha = .91), Physical Activity (3 items; alpha = .64), and Cross-Gender Desire (2 items; alpha = .47). Discriminant validity was demonstrated in terms of highly significant comparisons across the four groups. We conclude that the first 2 RCGQ-R scales show good psychometric qualities, but that the third scale needs to be further evaluated in a sample that includes women with gender identity disorder.

  13. Delivery by caesarean section and risk of childhood obesity: analysis of a Peruvian prospective cohort

    Directory of Open Access Journals (Sweden)

    Rodrigo M. Carrillo-Larco

    2015-06-01

    Full Text Available Objectives. We aimed to assess if Caesarean section is a risk factor for overnutrition in early- and late-childhood, and to assess the magnitude of the effect of child- versus family-related variables in these risk estimates.Methods. Longitudinal data from Peruvian children from the Young Lives Study was used. Outcomes assessed were overweight, obesity, overnutrition (overweight plus obesity, and central obesity (waist circumference at the age 5 (first follow-up and 7 (second follow-up years. The exposure of interests was delivery by Caesarean section. Relative risks (RR and 95% confidence intervals (95% CI were calculated using multivariable models adjusted for child-related (e.g., birth weight and family-related (e.g., maternal nutritional status variables.Results. At baseline, mean age was 11.7 (± 3.5 months and 50.1% were boys. Children born by Caesarean section were 15.6%. The 10.5% of the children were overweight and 2.4% were obese. For the obesity outcome, data from 6,038 and 9,625 children-years was included from baseline to the first and second follow-up, respectively. Compared to those who did not experience Caesarean delivery, the risk of having obesity was higher in the group born by Caesarean: RRs were higher at early-childhood (first follow-up: 2.25; 95% CI [1.36–3.74] than later in life (second follow-up: 1.57; 95% CI [1.02–2.41]. Family-related variables had a greater effect in attenuating the risk estimates for obesity at the first, than at the second follow-up.Conclusion. Our results suggest a higher probability of developing obesity, but not overweight, among children born by Caesarean section delivery. The magnitude of risk estimates decreased over time, and family-related variables had a stronger effect on the risk estimates at early-childhood.

  14. Geographical National Condition and Complex System

    Directory of Open Access Journals (Sweden)

    WANG Jiayao

    2016-01-01

    Full Text Available The significance of studying the complex system of geographical national conditions lies in rationally expressing the complex relationships of the “resources-environment-ecology-economy-society” system. Aiming to the problems faced by the statistical analysis of geographical national conditions, including the disunity of research contents, the inconsistency of range, the uncertainty of goals, etc.the present paper conducted a range of discussions from the perspectives of concept, theory and method, and designed some solutions based on the complex system theory and coordination degree analysis methods.By analyzing the concepts of geographical national conditions, geographical national conditions survey and geographical national conditions statistical analysis, as well as investigating the relationships between theirs, the statistical contents and the analytical range of geographical national conditions are clarified and defined. This investigation also clarifies the goals of the statistical analysis by analyzing the basic characteristics of the geographical national conditions and the complex system, and the consistency between the analysis of the degree of coordination and statistical analyses. It outlines their goals, proposes a concept for the complex system of geographical national conditions, and it describes the concept. The complex system theory provides new theoretical guidance for the statistical analysis of geographical national conditions. The degree of coordination offers new approaches on how to undertake the analysis based on the measurement method and decision-making analysis scheme upon which the complex system of geographical national conditions is based. It analyzes the overall trend via the degree of coordination of the complex system on a macro level, and it determines the direction of remediation on a micro level based on the degree of coordination among various subsystems and of single systems. These results establish

  15. Geographical inequalities in use of improved drinking water supply and sanitation across Sub-Saharan Africa: mapping and spatial analysis of cross-sectional survey data.

    Directory of Open Access Journals (Sweden)

    Rachel L Pullan

    2014-04-01

    Full Text Available Understanding geographic inequalities in coverage of drinking-water supply and sanitation (WSS will help track progress towards universal coverage of water and sanitation by identifying marginalized populations, thus helping to control a large number of infectious diseases. This paper uses household survey data to develop comprehensive maps of WSS coverage at high spatial resolution for sub-Saharan Africa (SSA. Analysis is extended to investigate geographic heterogeneity and relative geographic inequality within countries.Cluster-level data on household reported use of improved drinking-water supply, sanitation, and open defecation were abstracted from 138 national surveys undertaken from 1991-2012 in 41 countries. Spatially explicit logistic regression models were developed and fitted within a Bayesian framework, and used to predict coverage at the second administrative level (admin2, e.g., district across SSA for 2012. Results reveal substantial geographical inequalities in predicted use of water and sanitation that exceed urban-rural disparities. The average range in coverage seen between admin2 within countries was 55% for improved drinking water, 54% for use of improved sanitation, and 59% for dependence upon open defecation. There was also some evidence that countries with higher levels of inequality relative to coverage in use of an improved drinking-water source also experienced higher levels of inequality in use of improved sanitation (rural populations r = 0.47, p = 0.002; urban populations r = 0.39, p = 0.01. Results are limited by the quantity of WSS data available, which varies considerably by country, and by the reliability and utility of available indicators.This study identifies important geographic inequalities in use of WSS previously hidden within national statistics, confirming the necessity for targeted policies and metrics that reach the most marginalized populations. The presented maps and analysis approach

  16. Spatial Analysis of Phytophthora infestans Genotypes and Late Blight Severity on Tomato and Potato in the Del Fuerte Valley Using Geostatistics and Geographic Information Systems.

    Science.gov (United States)

    Jaime-Garcia, R; Orum, T V; Felix-Gastelum, R; Trinidad-Correa, R; Vanetten, H D; Nelson, M R

    2001-12-01

    ABSTRACT Genetic structure of Phytophthora infestans, the causal agent of potato and tomato late blight, was analyzed spatially in a mixed potato and tomato production area in the Del Fuerte Valley, Sinaloa, Mexico. Isolates of P. infestans were characterized by mating type, allozyme analysis at the glucose-6-phosphate isomerase and peptidase loci, restriction fragment length polymorphism with probe RG57, metalaxyl sensitivity, and aggressiveness to tomato and potato. Spatial patterns of P. infestans genotypes were analyzed by geographical information systems and geo-statistics during the seasons of 1994-95, 1995-96, and 1996-97. Spatial analysis of the genetic structure of P. infestans indicates that geographic substructuring of this pathogen occurs in this area. Maps displaying the probabilities of occurrence of mating types and genotypes of P. infestans, and of disease severity at a regional scale, were presented. Some genotypes that exhibited differences in epidemiologically important features such as metalaxyl sensitivity and aggressiveness to tomato and potato had a restricted spread and were localized in isolated areas. Analysis of late blight severity showed recurring patterns, such as the earliest onset of the disease in the area where both potato and tomato were growing, strengthening the hypothesis that infected potato tubers are the main source of primary inoculum. The information that geostatistical analysis provides might help improve management programs for late blight in the Del Fuerte Valley.

  17. The impact of the experience of childhood poverty on adult health-risk behaviors in Japan: a mediation analysis

    OpenAIRE

    Umeda, Maki; Oshio, Takashi; Fujii, Mayu

    2015-01-01

    Background The experience of childhood poverty has a long-lasting, adverse impact on physical health outcomes in adulthood. We examined the mediating effects of adult socioeconomic status (SES) and social support on the association between childhood poverty and adult health-risk behaviors. Methods Cross-sectional data collected from Japanese community residents (N = 3836) were used. A binary indicator of the experience of childhood poverty was constructed by utilizing retrospectively assessed...

  18. Characteristic fingerprint based on gingerol derivative analysis for discrimination of ginger (Zingiber officinale) according to geographical origin using HPLC-DAD combined with chemometrics.

    Science.gov (United States)

    Yudthavorasit, Soparat; Wongravee, Kanet; Leepipatpiboon, Natchanun

    2014-09-01

    Chromatographic fingerprints of gingers from five different ginger-producing countries (China, India, Malaysia, Thailand and Vietnam) were newly established to discriminate the origin of ginger. The pungent bioactive principles of ginger, gingerols and six other gingerol-related compounds were determined and identified. Their variations in HPLC profiles create the characteristic pattern of each origin by employing similarity analysis, hierarchical cluster analysis (HCA), principal component analysis (PCA) and linear discriminant analysis (LDA). As results, the ginger profiles tended to be grouped and separated on the basis of the geographical closeness of the countries of origin. An effective mathematical model with high predictive ability was obtained and chemical markers for each origin were also identified as the characteristic active compounds to differentiate the ginger origin. The proposed method is useful for quality control of ginger in case of origin labelling and to assess food authenticity issues.

  19. Analysis of Association Between Remotely Sensed (RS) Data and Soil Transmitted Helminthes Infection Using Geographical Information Systems (GIS): Boaco, Nicaragua

    Science.gov (United States)

    MorenoMadrinan, Max J.; Al-Hamdan, Mohammad Z.; Parajon, David G.; Rickman, Douglas L.; Luvall, Jeffrey; Podest, Erika; Parajon, Laura C.; Martinez, Roberto A.; Estes, Sue

    2011-01-01

    Soil-transmitted helminths are intestinal nematodes that can infect all members of a population but specially school-age children living in poverty. Infection can be significantly reversed with anthelmintic drug treatments and sanitation improvement. Implementation of effective public health programs requires reliable and updated information to identify areas at higher risk and to calculate amount of drug required. Geo-referenced in situ prevalence data will be overlaid over an ecological map derived from RS data using ARC Map 9.3 (ESRI). Prevalence data and RS data matching at the same geographical location will be analyzed for correlation and those variables from RS data that better correlate with prevalence will be included in a multivariate regression model. Temperature, vegetation, and distance to bodies of water will be inferred using data from Moderate-Resolution Imaging Spectroradiometer (MODIS) and Landsat TM and ETM+. Elevation will be estimated with data from The Shuttle Radar Topography Mission (SRTM). Prevalence and intensity of infections are determined by parasitological survey (Kato Katz) of children enrolled in rural schools in Boaco, Nicaragua, in the communities of El Roblar, Cumaica Norte, Malacatoya 1, and Malacatoya 2). This study will demonstrate the importance of an integrated GIS/RS approach to define sampling clusters without the need for any ground-based survey. Such information is invaluable to identify areas of high risk and to geographically target control programs that maximize cost-effectiveness and sanitation efforts.

  20. Effect of childhood obesity prevention programmes on blood lipids: a systematic review and meta-analysis.

    Science.gov (United States)

    Cai, L; Wu, Y; Cheskin, L J; Wilson, R F; Wang, Y

    2014-12-01

    We aimed to assess the effects of childhood obesity prevention programmes on blood lipids in high-income countries. We searched MEDLINE®, Embase, PsychInfo, CINAHL®, clinicaltrials.gov, and the Cochrane Library up to 22 April 2013 for relevant randomized controlled trials, quasi-experimental studies and natural experiments published in English. Studies were included if they implemented diet and/or physical activity intervention(s) with ≥1 year follow-up (or ≥6 months for school-based intervention studies) in 2-18-year-olds, and were excluded if they targeted only overweight/obese children, or those with a pre-existing medical condition. Seventeen studies were finally included. For total cholesterol, the pooled intervention effect was -0.97 mg dL(-1) [95% confidence interval (CI): -3.26, 1.32; P = 0.408]; for low-density lipoprotein cholesterol (LDL-C), -6.06 mg dL(-1) (95% CI: -11.09, -1.02; P = 0.018); for high-density lipoprotein cholesterol (HDL-C), 1.87 mg dL(-1) (95% CI: 0.39, 3.34; P = 0.013); and for triglycerides, -1.95 mg dL(-1) (95% CI: -4.94, 1.04; P = 0.202). Most interventions (70%) showed similar significant or no effects on adiposity- and lipids outcomes: 15% interventions improved both adiposity- and lipids outcomes; 55% had no significant effects on either. Childhood obesity prevention programmes had a significant desirable effect on LDL-C and HDL-C. Two-thirds of interventions showed similar significant or no effects in adiposity- and lipids outcomes. Assessing lipids outcomes provide additional useful information on obesity prevention programme benefits.

  1. Risk factors for childhood obesity at age 5: Analysis of the Millennium Cohort Study

    Directory of Open Access Journals (Sweden)

    Lyons Ronan A

    2009-12-01

    Full Text Available Abstract Background Weight at age 5 is a predictor for future health of the individual. This study examines risk factors for childhood obesity with a focus on ethnicity. Methods Data from the Millennium Cohort study were used. 17,561 singleton children of White/European (n = 15,062, Asian (n = 1,845 or African (n = 654 background were selected. Logistic regression and likelihood ratio tests were used to examine factors associated with obesity at age 5. All participants were interviewed in their own homes. The main exposures examined included; Birth weight, sedentary lifestyle, family health behaviours, ethnicity, education and income. Results Children with a sedentary lifestyle, large at birth, with high risk family health behaviours (overweight mothers, smoking near the child, missing breakfast and from a family with low income or low educational attainment, were more likely to be obese regardless of ethnicity. Feeding solid food before 3 months was associated with obesity in higher income White/European families. Even when controlling for socioeconomic status, ethnic background is an important independent risk factor for childhood obesity [Odds ratio of obesity; was 1.7 (95%CI: 1.2-2.3 for Asian and 2.7 (95%CI: 1.9-3.9 for African children, compared to White/European]. The final adjusted model suggests that increasing income does not have a great impact on lowering obesity levels, but that higher academic qualifications are associated with lower obesity levels [Odds of obesity: 0.63 (95%CI: 0.52-0.77 if primary carer leaves school after age 16 compared at age 16]. Conclusions Education of the primary carer is an important modifiable factor which can be targeted to address rising obesity levels in children. Interventions should be family centred supporting and showing people how they can implement lifestyle changes in their family.

  2. Characterization of the key aroma compounds in Turkish olive oils from different geographic origins by application of aroma extract dilution analysis (AEDA).

    Science.gov (United States)

    Kesen, Songul; Kelebek, Hasim; Selli, Serkan

    2014-01-15

    The aroma and aroma-active compounds of olive oils obtained from Nizip Yaglik (NY) and Kilis Yaglik (KY) cultivars and the effect of the geographical area (southern Anatolian and Aegean regions) on these compounds were analyzed by gas chromatography-mass spectrometry-olfactometry (GC-MS-O). For this purpose, two oil samples were obtained from their native geographical area including NY from Nizip province and KY from Kilis province (southern Anatolian region of Turkey). Another two oils of the same cultivar, NY-Bornova (NY-B) and KY-Bornova (KY-B), were obtained from the Olive Oil Research Center-Bornova, Izmir province (Aegean region of Turkey) to compare geographical effect on aroma and aroma-active compounds. Simultaneous distillation and extraction (SDE) with dichloromethane was used for extraction of volatile components. SDE gave a highly representative aromatic extract of the studied olive oil based on the sensory analysis. Totals of 61, 48, 59, and 48 aroma compounds were identified and quantified in olive oils obtained from NY, NY-B, KY, and KY-B cultivars, respectively. The results of principal component analysis (PCA) showed that the aroma profile of native region oils was discriminately different from those of Bornova region oils. Aldehydes and alcohols were qualitatively and quantitatively the most dominant volatiles in the oil samples. Aroma extract dilution analysis (AEDA) was used for the determination of aroma-active compounds of olive oils. The number of aroma-active compounds in native region oils was higher than in Bornova region oils. Within the compounds, aldehydes and alcohols were the largest aroma-active compounds in all olive oils.

  3. Epidemiology of childhood food allergy.

    Science.gov (United States)

    Dyer, Ashley A; Gupta, Ruchi

    2013-06-01

    Food allergy is a public health problem that affects nearly 6 million children in the United States. The extent to which children, families, and communities live with food allergies varies as much as the range of clinical symptoms associated with the disease itself. Food allergy is defined as the reproducible adverse event that elicits a pathologic immunoglobulin E (IgE)-mediated or non-IgE-mediated reaction. Once an allergic child ingests a specific food allergen, the reaction can result in clinical symptoms ranging from mild hives to life-threatening anaphylaxis.Not surprisingly, food allergies have been shown to limit social interactions and impair children's quality of life due to the ubiquity of food where children live, learn, and play. To ensure the safety of our children, the development of sound policy, clinical practice, and health programs must be informed by current research characterizing childhood food allergy at the population level. To set the stage for understanding the current evidence base, this article reviews: 1) epidemiology of childhood food allergy; 2) severity of symptoms; 3) geographic distribution of childhood food allergy; 4) tolerance; 5) economic impact of childhood food allergy; and 6) future directions in childhood food allergy epidemiological research.

  4. Tissue Doppler Imaging Combined with Advanced 12-Lead ECG Analysis Might Improve Early Diagnosis of Hypertrophic Cardiomyopathy in Childhood

    Science.gov (United States)

    Femlund, E.; Schlegel, T.; Liuba, P.

    2011-01-01

    Optimization of early diagnosis of childhood hypertrophic cardiomyopathy (HCM) is essential in lowering the risk of HCM complications. Standard echocardiography (ECHO) has shown to be less sensitive in this regard. In this study, we sought to assess whether spatial QRS-T angle deviation, which has shown to predict HCM in adults with high sensitivity, and myocardial Tissue Doppler Imaging (TDI) could be additional tools in early diagnosis of HCM in childhood. Methods: Children and adolescents with familial HCM (n=10, median age 16, range 5-27 years), and without obvious hypertrophy but with heredity for HCM (n=12, median age 16, range 4-25 years, HCM or sudden death with autopsy-verified HCM in greater than or equal to 1 first-degree relative, HCM-risk) were additionally investigated with TDI and advanced 12-lead ECG analysis using Cardiax(Registered trademark) (IMED Co Ltd, Budapest, Hungary and Houston). Spatial QRS-T angle (SA) was derived from Kors regression-related transformation. Healthy age-matched controls (n=21) were also studied. All participants underwent thorough clinical examination. Results: Spatial QRS-T angle (Figure/ Panel A) and septal E/Ea ratio (Figure/Panel B) were most increased in HCM group as compared to the HCM-risk and control groups (p less than 0.05). Of note, these 2 variables showed a trend toward higher levels in HCM-risk group than in control group (p=0.05 for E/Ea and 0.06 for QRS/T by ANOVA). In a logistic regression model, increased SA and septal E/Ea ratio appeared to significantly predict both the disease (Chi-square in HCM group: 9 and 5, respectively, p less than 0.05 for both) and the risk for HCM (Chi-square in HCM-risk group: 5 and 4 respectively, p less than 0.05 for both), with further increased predictability level when these 2 variables were combined (Chi-square 10 in HCM group, and 7 in HCM-risk group, p less than 0.01 for both). Conclusions: In this small material, Tissue Doppler Imaging and spatial mean QRS-T angle

  5. Childhood obesity.

    Science.gov (United States)

    Seth, Anju; Sharma, Rajni

    2013-04-01

    Childhood obesity is an issue of serious medical and social concern. In developing countries including India, it is a phenomenon seen in higher socioeconomic strata due to the adoption of a western lifestyle. Consumption of high calorie food, lack of physical activity and increased screen time are major risk factors for childhood obesity apart from other genetic, prenatal factors and socio-cultural practices. Obese children and adolescents are at increased risk of medical and psychological complications. Insulin resistance is commonly present especially in those with central obesity and manifests as dyslipidemia, type 2 diabetes mellitus, impaired glucose tolerance, hypertension, polycystic ovarian syndrome and metabolic syndrome. Obese children and adolescents often present to general physicians for management. The latter play a key role in prevention and treatment of obesity as it involves lifestyle modification of the entire family. This article aims at discussing the approach to diagnosis and work-up, treatment and preventive strategies for childhood obesity from a general physician's perspective.

  6. Childhood obesity

    DEFF Research Database (Denmark)

    Heitmann, Berit L; Koplan, Jeffrey; Lissner, Lauren

    2009-01-01

    Despite progress toward assuring the health of today's young population, the 21(st) century began with an epidemic of childhood obesity. There is general agreement that the situation must be addressed by means of primary prevention, but relatively little is known about how to intervene effectively....... The evidence behind the assumption that childhood obesity can be prevented was discussed critically in this roundtable symposium. Overall, there was general agreement that action is needed and that the worldwide epidemic itself is sufficient evidence for action. As the poet, writer, and scholar Wittner Bynner...... (1881-1968) wrote, "The biggest problem in the world could have been solved when it was small"....

  7. Nucleotide sequence analysis of Adh genes estimates the time of geographic isolation of the Bogota population of Drosophila pseudoobscura.

    Science.gov (United States)

    Schaeffer, S W; Miller, E L

    1991-01-01

    The population of Drosophila pseudoobscura at Bogota, Columbia, is geographically and partially reproductively isolated from populations in the main body of the species in North America. The degree of genetic differentiation and time of divergence between populations at Bogota and Apple Hill, CA, were estimated by comparison of 3388 nucleotides in the alcohol dehydrogenase region (Adh and Adh-Dup genes) of 18 strains. Of the 146 polymorphic nucleotide sites detected, 68 and 31 were unique to the Apple Hill and Bogota samples, respectively, and 53 were shared. On the basis of an observed net divergence per nucleotide site of 0.264% between the two samples, the Bogota and North American populations were estimated to have been separated for at least 155,000 years. This divergence time suggests that D. pseudoobscura extended its range from North America to South America in a period of Pleistocene glaciation, when habitat suitable for the species presumably existed in lowland Central America. PMID:2068088

  8. A Comparative Analysis of the Function of Coordination of Early Childhood Education and Care in France and Italy.

    Science.gov (United States)

    Baudelot, Olga; Rayna, Sylvie; Mayer, Susanna; Musatti, Tullia

    2003-01-01

    Surveyed local early childhood coordinators in France and Italy regarding their status, training, and tasks in order to compare the function of coordinating municipal early childhood education and care services in these two countries. Found impressive similarities in services, policies, and the function of coordination. Also found that service…

  9. Genome‐wide analysis of cytogenetic aberrations in ETV6/RUNX1‐positive childhood acute lymphoblastic leukaemia

    DEFF Research Database (Denmark)

    Borst, Louise; Wesolowska, Agata; Joshi, Tejal;

    2012-01-01

    The chromosomal translocation t(12;21) resulting in the ETV6/RUNX1 fusion gene is the most frequent structural cytogenetic abnormality among patients with childhood acute lymphoblastic leukaemia (ALL). We investigated 62 ETV6/RUNX1‐positive childhood ALL patients by single nucleotide polymorphism...

  10. The Analysis of Entropy Changes on the Evolutional Tendency of Geographical Environment%地理环境演化趋势的熵变化分析

    Institute of Scientific and Technical Information of China (English)

    王玉明

    2011-01-01

    地理环境系统的演化遵从热力学第二定律:系统的有序度变化与其总熵值变化反相关;当总熵变为负时,系统的有序度增大,从而有利于人类的生存与发展;反之亦然.结合前人有关地理环境熵变研究成果的分析表明:自然地理环境的自发演化是朝着有序化方向发展的;大规模人类活动对城市系统及人文地理环境的影响总体上是正面的,推动了其有序化发展;对自然地理环境的影响有正有负,正面影响表现为对低熵物质与能最的增量生产,体现在农产品增收、太阳能等新能源技术的应用和生态环境建设等方面;负面影响表现为消费与工业生产过程中对低熵物质与能量的消耗和向环境排放“三废”与散热,导致地理环境中低熵成分存量的减少和熵增扩大,已引起普遍担忧.自然地理环境“本底”演化的有序化指向和大幅增产低熵能源的技术可能性启示我们:通过引入更多低熵物质与能量和减少熵排放,可以促使地理环境的演化继续指向有序化方向.%The evolution of geographical environmental system obeys the second law of thermodynamics: the order degree changes of the system are anti-related to its total entropy changes. The order degree increases when the total entropy changes are negative, and it is useful for human beings' survival and development, and vice versa. The analysis shows that the spontaneous evolution of natural geographical environment is developing towards ordering. The impacts of large-scale human activities on city system and human geographical environment are totally positive, and push its ordering development; their impacts on natural geographical development are both positive and negative. The positive impact is mainly the incremental production of low-entropy material and energy, which has been reflected in the increase of agricultural products and the application of new energy technology, such as

  11. Preliminary Study on Geographical Distribution and Evolutionary Relationships Between Cultivated and Wild Adzuki Bean (Vigna angularis var. angularis and var. nipponensis) by AFLP Analysis

    Institute of Scientific and Technical Information of China (English)

    ZONG Xu-xiao; Duncan Vaughan; Norihiko Tomooka; Akito Kaga; WANG Xin-wang; GUAN Jian-ping; WANG Shu-min

    2003-01-01

    A set of representative 146 adzuki (Vigna angularis var. angularis, and var. nipponensis)germplasm from 6 Asian countries traditionally for adzuki bean production, together with an out group stand-ard rice bean (Vigna umbellata), were analyzed by AFLP methodology using 12 informative primer pairs.313 unambiguous polymorphic bands were created. According to the dendrogram by cluster analysis based onAFLP banding, 143 of the accessions were distinct and revealed enough genetic diversity for identification andclassification of accessions within Vigna angularis. A neighbor joining tree was generated using newly devel-oped Innan's nucleotide diversity estimate from the AFLP data. From analysis, 7 distinct evolutionary groups,named as "Chinese cultivated", "Japanese cultivated", "Japanese complex-Korean cultivated", "Chinesewild", "China Taiwan wild", "Nepal-Bhutan cultivated" and "Hymalayan wild", were detected. Nucleotidediversity with geographical distribution of each group is discussed, regarding the evolutionary relationships be-tween wild and cultivated adzuki beans. The preliminary results indicated that cultivated adzuki bean should bedomesticated from at least 4 progenitors in at least 3 geographical origins.

  12. Childhood Obesity

    Centers for Disease Control (CDC) Podcasts

    2013-08-06

    In this podcast, Dr. Tom Frieden, CDC Director, discusses the decrease in childhood obesity rates and what strategies have been proven to work to help our children grow up and thrive.  Created: 8/6/2013 by National Center for Injury Prevention and Control.   Date Released: 3/6/2014.

  13. Childhood Obesity

    Science.gov (United States)

    Yuca, Sevil Ari, Ed.

    2012-01-01

    This book aims to provide readers with a general as well as an advanced overview of the key trends in childhood obesity. Obesity is an illness that occurs due to a combination of genetic, environmental, psychosocial, metabolic and hormonal factors. The prevalence of obesity has shown a great rise both in adults and children in the last 30 years.…

  14. Childhood obesity.

    Science.gov (United States)

    Strauss, R

    1999-01-01

    Approximately 10% of children are obese. Twin and adoption studies demonstrate a large genetic component to obesity, especially in adults. However, the increasing prevalence of obesity over the last 20 years can only be explained by environmental factors. In most obese individuals, no measurable differences in metabolism can be detected. Few children engage in regular physical activity. Obese children and adults uniformly underreport the amount of food they eat. Obesity is particularly related to increased consumption of high-fat foods. BMI is a quick and easy way to screen for childhood obesity. Treating childhood obesity relies on positive family support and lifestyle changes involving the whole family. Food preferences are influenced early by parental eating habits, and when developed in childhood, they tend to remain fairly constant into adulthood. Children learn to be active or inactive from their parents. In addition, physical activity (or more commonly, physical inactivity) habits that are established in childhood tend to persist into adulthood. Weight loss is usually followed by changes in appetite and metabolism, predisposing individuals to regain their weight. However, when the right family dynamics exist--a motivated child with supportive parents--long-term success is possible.

  15. Sex Differences in the Prevalence of Oppositional Defiant Disorder During Middle Childhood: a Meta-Analysis.

    Science.gov (United States)

    Demmer, David H; Hooley, Merrilyn; Sheen, Jade; McGillivray, Jane A; Lum, Jarrad A G

    2017-02-01

    This review provides a meta-analysed male:female prevalence ratio of oppositional defiant disorder (ODD) during middle childhood in non-referred children. It also analyses sex differences in prevalence across cultures and over time. A systematic search for studies via the following sources was conducted: PsycInfo, Web of Knowledge, Medline Complete, Scopus, EMBASE, InfoRMIT, Psychological and Behavioural Sciences Collection, Cochrane Library, PubMed and ProQuest Health. The studies presented in two previous systematic reviews were also added to the search results. Inclusion/exclusion criteria were then applied and final studies were appraised for their methodological quality. Nineteen independent effect sizes met full inclusion criteria (aggregated sample N = 44,107). Overall, the prevalence of ODD was significantly higher in boys than girls (RR = 1.59, 95 % CI [1.36, 1.86], p  0.05). Sex differences in prevalence were significant in studies published prior to and post the year 2000 (RR = 1.57, 95 % CI [1.22, 2.02], p  0.05). The sex differences in ODD prevalence are discussed within the context of (i) predominant theories of sex differences in externalising behaviours, and (ii) departure from the sex-differences pattern found for other disruptive behavioural disorders.

  16. Quantitative EEG analysis of the maturational changes associated with childhood absence epilepsy

    Science.gov (United States)

    Rosso, O. A.; Hyslop, W.; Gerlach, R.; Smith, R. L. L.; Rostas, J. A. P.; Hunter, M.

    2005-10-01

    This study aimed to examine the background electroencephalography (EEG) in children with childhood absence epilepsy, a condition whose presentation has strong developmental links. EEG hallmarks of absence seizure activity are widely accepted and there is recognition that the bulk of inter-ictal EEG in this group is normal to the naked eye. This multidisciplinary study aimed to use the normalized total wavelet entropy (NTWS) (Signal Processing 83 (2003) 1275) to examine the background EEG of those patients demonstrating absence seizure activity, and compare it with children without absence epilepsy. This calculation can be used to define the degree of order in a system, with higher levels of entropy indicating a more disordered (chaotic) system. Results were subjected to further statistical analyses of significance. Entropy values were calculated for patients versus controls. For all channels combined, patients with absence epilepsy showed (statistically significant) lower entropy values than controls. The size of the difference in entropy values was not uniform, with certain EEG electrodes consistently showing greater differences than others.

  17. High resolution melting curve analysis, a rapid and affordable method for mutation analysis in childhood acute myeloid leukemia

    Directory of Open Access Journals (Sweden)

    Yin eLiu

    2014-09-01

    Full Text Available Background: Molecular genetic alterations with prognostic significance have been described in childhood acute myeloid leukemia (AML. The aim of this study was to establish cost-effective techniques to detect mutations of FMS-like tyrosine kinase 3 (FLT3, Nucleophosmin 1 (NPM1, and a partial tandem duplication within the mixed lineage leukemia (MLL-PTD genes in childhood AML. Procedure: Ninety-nine children with newly diagnosed AML were included in this study. We developed a fluoresent dye SYTO-82 based high resolution melting curve (HRM anaylsis to detect FLT3 internal tandem duplication (FLT3-ITD, FLT3 tyrosine kinase domain (FLT3-TKD and NPM1 mutations. MLL-PTD was screened by real-time quantitative PCR. Results: The HRM methodology correlated well with gold standard Sanger sequencing with less cost. Among the 99 patients studied, the FLT3-ITD mutation was associated with significantly worse event free survival (EFS. Patients with the NPM1 mutation had significantly better EFS and overall survival. However, HRM was not sensitive enough for minimal residual disease monitoring. Conclusions: HRM was a rapid and efficient method for screening of FLT3 and NPM1 gene mutations. It was both affordable and accurate, especially in resource underprivileged regions. Our results indicated that HRM could be a useful clinical tool for rapid and cost effective screening of the FLT3 and NPM1 mutations in AML patients.

  18. Incidence of viral infection detected by PCR and real-time PCR in childhood community-acquired pneumonia: a meta-analysis.

    Science.gov (United States)

    Wang, Min; Cai, Feng; Wu, Xiaodong; Wu, Ting; Su, Xin; Shi, Yi

    2015-04-01

    Several studies examining the incidence of viral infection in childhood community-acquired pneumonia (CAP) utilizing polymerase chain reaction (PCR) or real-time PCR methods have been reported. We systematically searched Pubmed and Embase for studies reporting the incidence of respiratory viral infection in childhood CAP. The pooled incidences of viral infection were calculated with a random-effects model. Sources of heterogeneity were explored by subgroup analysis and a univariant metaregression analysis. We included 21 eligible reports in our study. We found significant heterogeneity on the incidence of viral infection in childhood CAP. The random effects pooled incidence was 57.4% (95% confidence interval (CI): 50.8-64.1). The pooled incidence of mixed infection was 29.3% (95%CI: 23.0-35.6) with considerable heterogeneity. The pooled incidence of mixed infection was 29.3% (95%CI: 23.0-35.6). Rhinovirus, respiratory syncytial virus (RSV) and bocavirus were found to be the three most common viruses in childhood CAP. We also demonstrated that respiratory viruses were detected in 76.1% of patients aged ≤ 1 year, 63.1% of patients aged 2-5 years and 27.9% of patients aged ≥ 6 years. We conclude that respiratory viruses are widely detected in paediatric patients with CAP by PCR or real-time PCR methods. More than half of viral infections are probably concurrent with bacterial infections. Rhinovirus, RSV and bocavirus are the three most frequent viruses identified in childhood CAP; the incidence of viral infection decreased with age.

  19. Airports Geographic Information System -

    Data.gov (United States)

    Department of Transportation — The Airports Geographic Information System maintains the airport and aeronautical data required to meet the demands of the Next Generation National Airspace System....

  20. 454 Pyrosequencing Analysis of Fungal Assemblages from Geographically Distant, Disparate Soils Reveals Spatial Patterning and a Core Mycobiome

    Directory of Open Access Journals (Sweden)

    Mariangela Girlanda

    2013-02-01

    Full Text Available Identifying a soil core microbiome is crucial to appreciate the established microbial consortium, which is not usually subjected to change and, hence, possibly resistant/resilient to disturbances and a varying soil context. Fungi are a major part of soil biodiversity, yet the mechanisms driving their large-scale ecological ranges and distribution are poorly understood. The degree of fungal community overlap among 16 soil samples from distinct ecosystems and distant geographic localities (truffle grounds, a Mediterranean agro-silvo-pastoral system, serpentine substrates and a contaminated industrial area was assessed by examining the distribution of fungal ITS1 and ITS2 sequences in a dataset of 454 libraries. ITS1 and ITS2 sequences were assigned to 1,660 and 1,393 Operational Taxonomic Units (OTUs; as defined by 97% sequence similarity, respectively. Fungal beta-diversity was found to be spatially autocorrelated. At the level of individual OTUs, eight ITS1 and seven ITS2 OTUs were found in all soil sample groups. These ubiquitous taxa comprised generalist fungi with oligotrophic and chitinolytic abilities, suggesting that a stable core of fungi across the complex soil fungal assemblages is either endowed with the capacity of sustained development in the nutrient-poor soil conditions or with the ability to exploit organic resources (such as chitin universally distributed in soils.

  1. Network sensitivity to geographical configuration

    CERN Document Server

    Searle, A C; McClelland, D E; Searle, Antony C; Scott, Susan M; Clelland, David E Mc

    2002-01-01

    Gravitational wave astronomy will require the coordinated analysis of data from the global network of gravitational wave observatories. Questions of how to optimally configure the global network naturally arise in this context. We propose a formalism to compare different configurations of the network, using both the coincident network analysis method and the coherent network analysis method, and construct a model to compute a figure-of-merit based on the detection rate for a population of standard-candle binary inspirals. We find that this measure of network quality is very sensitive to the geographic location of component detectors under a coincident network analysis, but comparatively insensitive under a coherent network analysis.

  2. La mejora de la educacion infantil desde el analisis del pensamiento practico de sus educadores. [The Improvement of Early Childhood Education from an Analysis of the Practical Thinking of Early Childhood Educators.

    Science.gov (United States)

    Argos, Javier

    2000-01-01

    Discusses proposals for the innovation and development of early childhood education practice, based on findings from case studies on the practical knowledge of four experienced female early childhood educators. Argues that improving early childhood education should be based on its reasons and purposes rather than content or method. (JPB)

  3. Parental Supply of Alcohol in Childhood and Risky Drinking in Adolescence: Systematic Review and Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Sonia Sharmin

    2017-03-01

    Full Text Available Whether parental supply of alcohol affects the likelihood of later adolescent risky drinking remains unclear. We conducted a systematic review and meta-analysis to synthesize findings from longitudinal studies investigating this association. We searched eight electronic databases up to 10 September 2016 for relevant terms and included only original English language peer-reviewed journal articles with a prospective design. Two reviewers independently screened articles, extracted data and assessed risk of bias. Seven articles met inclusion criteria, six of which used analytic methods allowing for meta-analysis. In all seven studies, the follow-up period was ≥12 months and attrition ranged from 3% to 15%. Parental supply of alcohol was associated with subsequent risky drinking (odds ratio = 2.00, 95% confidence interval = 1.72, 2.32; however, there was substantial risk of confounding bias and publication bias. In all studies, measurement of exposure was problematic given the lack of distinction between parental supply of sips of alcohol versus whole drinks. In conclusion, parental supply of alcohol in childhood is associated with an increased likelihood of risky drinking later in adolescence. However, methodological limitations preclude a causal inference. More robust longitudinal studies are needed, with particular attention to distinguishing sips from whole drinks, measurement of likely confounders, and multivariable adjustment.

  4. Parental Supply of Alcohol in Childhood and Risky Drinking in Adolescence: Systematic Review and Meta-Analysis

    Science.gov (United States)

    Sharmin, Sonia; Kypri, Kypros; Khanam, Masuma; Wadolowski, Monika; Bruno, Raimondo; Mattick, Richard P.

    2017-01-01

    Whether parental supply of alcohol affects the likelihood of later adolescent risky drinking remains unclear. We conducted a systematic review and meta-analysis to synthesize findings from longitudinal studies investigating this association. We searched eight electronic databases up to 10 September 2016 for relevant terms and included only original English language peer-reviewed journal articles with a prospective design. Two reviewers independently screened articles, extracted data and assessed risk of bias. Seven articles met inclusion criteria, six of which used analytic methods allowing for meta-analysis. In all seven studies, the follow-up period was ≥12 months and attrition ranged from 3% to 15%. Parental supply of alcohol was associated with subsequent risky drinking (odds ratio = 2.00, 95% confidence interval = 1.72, 2.32); however, there was substantial risk of confounding bias and publication bias. In all studies, measurement of exposure was problematic given the lack of distinction between parental supply of sips of alcohol versus whole drinks. In conclusion, parental supply of alcohol in childhood is associated with an increased likelihood of risky drinking later in adolescence. However, methodological limitations preclude a causal inference. More robust longitudinal studies are needed, with particular attention to distinguishing sips from whole drinks, measurement of likely confounders, and multivariable adjustment. PMID:28282955

  5. Childhood trauma and personality disorder criterion counts: a co-twin control analysis.

    Science.gov (United States)

    Berenz, Erin C; Amstadter, Ananda B; Aggen, Steven H; Knudsen, Gun Peggy; Reichborn-Kjennerud, Ted; Gardner, Charles O; Kendler, Kenneth S

    2013-11-01

    Correlational studies consistently report relationships between childhood trauma (CT) and most personality disorder (PD) criteria and diagnoses. However, it is not clear whether CT is directly related to PDs or whether common familial factors (i.e., shared environment and/or genetic factors) better account for that relationship. The current study used a cotwin control design to examine support for a direct effect of CT on PD criterion counts. Participants were from the Norwegian Twin Registry (N = 2,780), including a subset (n = 898) of twin pairs (449 pairs, 45% monozygotic [MZ]) discordant for CT meeting DSM-IV Posttraumatic Stress Disorder Criterion A. All participants completed the Norwegian version of the Structured Interview for DSM-IV Personality. Significant associations between CT and all PD criterion counts were detected in the general sample; however, the magnitude of observed effects was small, with CT accounting for no more than approximately 1% of variance in PD criterion counts. A significant, yet modest, interactive effect was detected for sex and CT on Schizoid and Schizotypal PD criterion counts, with CT being related to these disorders among women but not men. After common familial factors were accounted for in the discordant twin sample, CT was significantly related to Borderline and Antisocial PD criterion counts, but no other disorders; however, the magnitude of observed effects was quite modest (r2 = .006 for both outcomes), indicating that the small effect observed in the full sample is likely better accounted for by common genetic and/or environmental factors. CT does not appear to be a key factor in PD etiology.

  6. Rapid discrimination of the geographical origins of an oolong tea (anxi-tieguanyin) by near-infrared spectroscopy and partial least squares discriminant analysis.

    Science.gov (United States)

    Yan, Si-Min; Liu, Jun-Ping; Xu, Lu; Fu, Xian-Shu; Cui, Hai-Feng; Yun, Zhen-Yu; Yu, Xiao-Ping; Ye, Zi-Hong

    2014-01-01

    This paper focuses on a rapid and nondestructive way to discriminate the geographical origin of Anxi-Tieguanyin tea by near-infrared (NIR) spectroscopy and chemometrics. 450 representative samples were collected from Anxi County, the original producing area of Tieguanyin tea, and another 120 Tieguanyin samples with similar appearance were collected from unprotected producing areas in China. All these samples were measured by NIR. The Stahel-Donoho estimates (SDE) outlyingness diagnosis was used to remove the outliers. Partial least squares discriminant analysis (PLSDA) was performed to develop a classification model and predict the authenticity of unknown objects. To improve the sensitivity and specificity of classification, the raw data was preprocessed to reduce unwanted spectral variations by standard normal variate (SNV) transformation, taking second-order derivatives (D2) spectra, and smoothing. As the best model, the sensitivity and specificity reached 0.931 and 1.000 with SNV spectra. Combination of NIR spectrometry and statistical model selection can provide an effective and rapid method to discriminate the geographical producing area of Anxi-Tieguanyin.

  7. Rapid Discrimination of the Geographical Origins of an Oolong Tea (Anxi-Tieguanyin by Near-Infrared Spectroscopy and Partial Least Squares Discriminant Analysis

    Directory of Open Access Journals (Sweden)

    Si-Min Yan

    2014-01-01

    Full Text Available This paper focuses on a rapid and nondestructive way to discriminate the geographical origin of Anxi-Tieguanyin tea by near-infrared (NIR spectroscopy and chemometrics. 450 representative samples were collected from Anxi County, the original producing area of Tieguanyin tea, and another 120 Tieguanyin samples with similar appearance were collected from unprotected producing areas in China. All these samples were measured by NIR. The Stahel-Donoho estimates (SDE outlyingness diagnosis was used to remove the outliers. Partial least squares discriminant analysis (PLSDA was performed to develop a classification model and predict the authenticity of unknown objects. To improve the sensitivity and specificity of classification, the raw data was preprocessed to reduce unwanted spectral variations by standard normal variate (SNV transformation, taking second-order derivatives (D2 spectra, and smoothing. As the best model, the sensitivity and specificity reached 0.931 and 1.000 with SNV spectra. Combination of NIR spectrometry and statistical model selection can provide an effective and rapid method to discriminate the geographical producing area of Anxi-Tieguanyin.

  8. Observed & Modeled Changes in the Onset of Spring: A Preliminary Comparative Analysis by Geographic Regions of the USA

    Science.gov (United States)

    Enquist, C.

    2012-12-01

    qualitatively test SI-x output and synthesize climate-linked regional variation in phenological events across the United States, we conducted a review of the recent phenology literature and assembled this information into 8 geographic regions. Additionally, we compared these outputs to analyses of species data found in the USA National Phenology Network database. We found that (1) all outputs showed advancement of spring onset across regions and taxa, despite great variability in species and site-level response, (2) many studies suggest that there may be evolutionary selection for organisms that track climatic changes, (3) although some organisms may benefit from lengthening growing seasons, there may be a cost, such as susceptibility to late frost, or "false springs," and (4) invasive organisms may have more capacity to track these changes than natives. More work is needed to (1) better understand precipitation and hydrology related cues and (2) understand the demographic consequences of trophic mismatch and effects on ecosystem processes and services. Next steps in this research include performing quantitative analyses to further explore if SI-x can be used to indicate and forecast changes in ecological and hydrological processes across geographic regions.

  9. Environmental geographic information system.

    Energy Technology Data Exchange (ETDEWEB)

    Peek, Dennis W; Helfrich, Donald Alan; Gorman, Susan

    2010-08-01

    This document describes how the Environmental Geographic Information System (EGIS) was used, along with externally received data, to create maps for the Site-Wide Environmental Impact Statement (SWEIS) Source Document project. Data quality among the various classes of geographic information system (GIS) data is addressed. A complete listing of map layers used is provided.

  10. Analysis of Impact of Geographical Environment and Socio-economic Factors on the Spatial Distribution of Kaohsiung Dengue Fever Epidemic

    Science.gov (United States)

    Hsu, Wei-Yin; Wen, Tzai-Hung; Yu, Hwa-Lung

    2013-04-01

    Taiwan is located in subtropical and tropical regions with high temperature and high humidity in the summer. This kind of climatic condition is the hotbed for the propagation and spread of the dengue vector mosquito. Kaohsiung City has been the worst dengue fever epidemic city in Taiwan. During the study period, from January 1998 to December 2011, Taiwan CDC recorded 7071 locally dengue epidemic cases in Kaohsiung City, and the number of imported case is 118. Our research uses Quantile Regression, a spatial infection disease distribution, to analyze the correlation between dengue epidemic and geographic environmental factors and human society factors in Kaohsiung. According to our experiment statistics, agriculture and natural forest have a positive relation to dengue fever(5.5~34.39 and 3.91~15.52). The epidemic will rise when the ratio for agriculture and natural forest increases. Residential ratio has a negative relation for quantile 0.1 to 0.4(-0.005~-0.78), and a positive relation for quantile 0.5 to0.9(0.01~18.0) . The mean income is also a significant factor in social economy field, and it has a negative relation to dengue fever(-0.01~-0.04). Conclusion from our research is that the main factor affecting the degree of dengue fever in predilection area is the residential proportion and the ratio of agriculture and natural forest plays an important role affecting the degree of dengue fever in non predilection area. Moreover, the serious epidemic area located by regression model is the same as the actual condition in Kaohsiung. This model can be used to predict the serious epidemic area of dengue fever and provide some references for the Health Agencies

  11. [Geographic distribution of birds in the Sierra Madre Oriental of San Luis Potosi, Mexico: a regional analysis of conservation status].

    Science.gov (United States)

    Sahagún Sánchez, Francisco Javier; Navarro, Jaime Castro; Reyes Hernández, Humberto

    2013-06-01

    The Sierra Madre Oriental region in the mexican state of San Luis Potosi is a relevant place for bird conservation at a country level. Therefore the main goal of this study was to analyze the geographic patterns of distribution and the conservation current state of the birds, to support the needs to expand the conservation areas in the future. Data was collected from various databases of zoological museums and collections, and field sampling methods conducted from January 2009 to May 2011. Potential distributions were modeled for 284 species using GARP software and then a map was developed to determine areas with favorable environmental characteristics for the distribution of species richness. Finally, the importance of conservation areas for the potential distribution of birds in the region was evaluated. A total of 359 species were recorded of which 71.4% are permanent residents, 19% are winter migrants and 4% are summer residents. From this total, 41 species were endemic, 47 were species at risk and 149 were neotropical migrants. The largest species richness correspond to oak forests, cloud forests, and tropical moist forests located at altitudes from 100m to 1 500m. Their potential distribution was concentrated towards the center and Southeast of the study area. Only 10% of areas with a high potential conservation was included in areas of priority for bird conservation (AICA) and just 3% of all potential areas were under some governmental category of protection. However, no conservation area has a management plan currently applied and monitored. The information generated is important for the development of management proposals for birds conservation in the region.

  12. Childhood pancreatitis.

    Science.gov (United States)

    Uretsky, G; Goldschmiedt, M; James, K

    1999-05-01

    Acute pancreatitis is a rare finding in childhood but probably more common than is generally realized. This condition should be considered in the evaluation of children with vomiting and abdominal pain, because it can cause significant morbidity and mortality. Clinical suspicion is required to make the diagnosis, especially when the serum amylase concentration is normal. Recurrent pancreatitis may be familial as a result of inherited biochemical or anatomic abnormalities. Patients with hereditary pancreatitis are at high risk for pancreatic cancer.

  13. Childhood rhabdomyosarcoma.

    Science.gov (United States)

    Córdoba Rovira, S M; Inarejos Clemente, E J

    Rhabdomyosarcoma is the most common soft-tissue sarcoma in children; it can appear in any part of the body. Its biological behavior varies widely, and despite the absence of specific clinical or radiological characteristics, rhabdomyosarcoma should be taken into account in the differential diagnosis of solid tumors in children. This review focuses primarily on the imaging findings and anatomical distribution of the histological subtypes of childhood rhabdomyosarcoma and secondarily on the differential findings in histological studies.

  14. Analysis of mitochondrial DNA sequences in childhood encephalomyopathies reveals new disease-associated variants.

    Directory of Open Access Journals (Sweden)

    Aijaz A Wani

    Full Text Available BACKGROUND: Mitochondrial encephalomyopathies are a heterogeneous group of clinical disorders generally caused due to mutations in either mitochondrial DNA (mtDNA or nuclear genes encoding oxidative phosphorylation (OXPHOS. We analyzed the mtDNA sequences from a group of 23 pediatric patients with clinical and morphological features of mitochondrial encephalopathies and tried to establish a relationship of identified variants with the disease. METHODOLOGY/PRINCIPLE FINDINGS: Complete mitochondrial genomes were amplified by PCR and sequenced by automated DNA sequencing. Sequencing data was analyzed by SeqScape software and also confirmed by BLASTn program. Nucleotide sequences were compared with the revised Cambridge reference sequence (CRS and sequences present in mitochondrial databases. The data obtained shows that a number of known and novel mtDNA variants were associated with the disease. Most of the non-synonymous variants were heteroplasmic (A4136G, A9194G and T11916A suggesting their possibility of being pathogenic in nature. Some of the missense variants although homoplasmic were showing changes in highly conserved amino acids (T3394C, T3866C, and G9804A and were previously identified with diseased conditions. Similarly, two other variants found in tRNA genes (G5783A and C8309T could alter the secondary structure of Cys-tRNA and Lys-tRNA. Most of the variants occurred in single cases; however, a few occurred in more than one case (e.g. G5783A and A10149T. CONCLUSIONS AND SIGNIFICANCE: The mtDNA variants identified in this study could be the possible cause of mitochondrial encephalomyopathies with childhood onset in the patient group. Our study further strengthens the pathogenic score of known variants previously reported as provisionally pathogenic in mitochondrial diseases. The novel variants found in the present study can be potential candidates for further investigations to establish the relationship between their incidence and role

  15. Volunteered Geographic Information in Natural Hazard Analysis: A Systematic Literature Review of Current Approaches with a Focus on Preparedness and Mitigation

    Directory of Open Access Journals (Sweden)

    Carolin Klonner

    2016-06-01

    Full Text Available With the rise of new technologies, citizens can contribute to scientific research via Web 2.0 applications for collecting and distributing geospatial data. Integrating local knowledge, personal experience and up-to-date geoinformation indicates a promising approach for the theoretical framework and the methods of natural hazard analysis. Our systematic literature review aims at identifying current research and directions for future research in terms of Volunteered Geographic Information (VGI within natural hazard analysis. Focusing on both the preparedness and mitigation phase results in eleven articles from two literature databases. A qualitative analysis for in-depth information extraction reveals auspicious approaches regarding community engagement and data fusion, but also important research gaps. Mainly based in Europe and North America, the analysed studies deal primarily with floods and forest fires, applying geodata collected by trained citizens who are improving their knowledge and making their own interpretations. Yet, there is still a lack of common scientific terms and concepts. Future research can use these findings for the adaptation of scientific models of natural hazard analysis in order to enable the fusion of data from technical sensors and VGI. The development of such general methods shall contribute to establishing the user integration into various contexts, such as natural hazard analysis.

  16. A Cost-Benefit Analysis of Early Childhood Intervention: Evidence from a Randomised Evaluation of a Parenting Programme

    OpenAIRE

    O'Neill, Donal

    2009-01-01

    A number of researchers and policy makers have recently argued that the most effective way of dealing with long-run disadvantage and the intergenerational transmission of poverty is through early childhood intervention and in particular policies aimed at supporting the family in early childhood development. In this paper we carry out a randomised evaluation of one such programme aimed at improving the skills and parenting strategies of parents, particularly those who find their child's behavi...

  17. Childhood Obesity Facts

    Science.gov (United States)

    ... Breastfeeding Micronutrient Malnutrition State and Local Programs Childhood Obesity Facts Recommend on Facebook Tweet Share Compartir On ... Children (WIC) Program, 2000–2014 Prevalence of Childhood Obesity in the United States, 2011-2014 Childhood obesity ...

  18. GNIS: Geographic Names Information Systems - All features (2013)

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The Geographic Names Information System (GNIS) is the Federal standard for geographic nomenclature. The U.S. Geological Survey developed the GNIS for the U.S. Board...

  19. [Close relationships in childhood and adulthood from the viewpoint of structural analysis of social behavior (SASB) and attachment theory].

    Science.gov (United States)

    Neumann, Eva; Tress, Wolfgang

    2007-01-01

    Two theoretical approaches to interpersonal experiences and behavior are empirically related to each other: Structural Analysis of Social Behavior (SASB) and attachment theory. The focus is on the most important relationships during life-span: relationships with mother and father in childhood, which were measured retrospectively, and romantic relationships in adulthood. 93 outpatients of a psychosomatic clinic took part in the study. Self-report measures were used to assess SASB-dimensions affiliation and autonomy and attachment variables (Intrex short form, Short measure of attachment to parents, Bochum Adult Attachment Questionnaire). Affiliation was strongly related to attachment to mother, father and romantic partner. Subjects classified as secure with respect to attachment to parents reported higher levels of affiliation than subjects classified as anxious or avoidant. Correspondingly, affiliation was negatively correlated with avoidance and anxiety in adult attachment to the romantic partner. On the other hand, autonomy was shown to be unrelated to attachment variables. Results indicate that the SASB-dimension affiliation and attachment security are closely associated.

  20. Associations between maternal and paternal parenting behaviors, anxiety and its precursors in early childhood: A meta-analysis.

    Science.gov (United States)

    Möller, Eline L; Nikolić, Milica; Majdandžić, Mirjana; Bögels, Susan M

    2016-04-01

    In this meta-analysis we investigated differential associations between maternal and paternal parenting behaviors (overcontrol, overprotection, overinvolvement, autonomy granting, challenging parenting) and anxiety and its precursors (fearful temperament, behavioral inhibition, shyness) in children (0-5years). Two meta-analyses were conducted, one for mothers (k=28, N=5,728), and one for fathers (k=12, N=1,019). In general, associations between parenting and child anxiety were small. Associations between child anxiety and overcontrol, overprotection, and overinvolvement did not differ for mothers and fathers. Maternal autonomy granting was not significantly related to child anxiety, and no studies examined fathers' autonomy granting. A significant difference was found for challenging parenting; mothers' challenging parenting was not significantly related to child anxiety, whereas fathers' challenging parenting was related to less child anxiety. Post-hoc meta-analyses revealed that mothers' and fathers' parenting was more strongly related to children's anxiety symptoms than to child anxiety precursors. Moreover, the association between parenting and child anxiety symptoms was stronger for fathers than for mothers. In conclusion, although parenting plays only a small role in early childhood anxiety, fathers' parenting is at least as important as mothers'. Paternal challenging behavior even seems more important than maternal challenging behavior. Research is needed to determine whether challenging fathering can prevent child anxiety development.

  1. Household food insecurity and childhood overweight in Jamaica and Québec: a gender-based analysis

    Directory of Open Access Journals (Sweden)

    Gordon-Strachan Georgiana

    2011-03-01

    Full Text Available Abstract Background Childhood overweight is not restricted to developed countries: a number of lower- and middle-income countries are struggling with the double burden of underweight and overweight. Another public health problem that concerns both developing and, to a lesser extent, developed countries is food insecurity. This study presents a comparative gender-based analysis of the association between household food insecurity and overweight among 10-to-11-year-old children living in the Canadian province of Québec and in the country of Jamaica. Methods Analyses were performed using data from the 2008 round of the Québec Longitudinal Study of Child Development and the Jamaica Youth Risk and Resiliency Behaviour Survey of 2007. Cross-sectional data were obtained from 1190 10-year old children in Québec and 1674 10-11-year-old children in Jamaica. Body mass index was derived using anthropometric measurements and overweight was defined using Cole's age- and sex-specific criteria. Questionnaires were used to collect data on food insecurity. The associations were examined using chi-square tests and multivariate regression models were used to estimate odds ratios (OR and 95% confidence intervals. Results The prevalence of overweight was 26% and 11% (p Conclusions Public health interventions which aim to stem the epidemic of overweight/obesity should consider gender differences and other family factors associated with overweight/obesity in both developed and developing countries.

  2. Childhood sexual abuse, intimate partner violence during pregnancy, and posttraumatic stress symptoms following childbirth: a path analysis.

    Science.gov (United States)

    Oliveira, Aline Gaudard E Silva de; Reichenheim, Michael Eduardo; Moraes, Claudia Leite; Howard, Louise Michele; Lobato, Gustavo

    2016-12-28

    The aim of the study was to explore the pathways by which childhood sexual abuse (CSA), psychological and physical intimate partner violence (IPV) during pregnancy, and other covariates relate to each other and to posttraumatic stress disorder (PTSD) symptoms in the postpartum period. The sample comprised 456 women who gave birth at a maternity service for high-risk pregnancies in Rio de Janeiro, Brazil, interviewed at 6-8 weeks after birth. A path analysis was carried out to explore the postulated pathways between exposures and outcome. Trauma History Questionnaire, Conflict Tactics Scales and Posttraumatic Stress Disorder Checklist were used to assess information about exposures of main interest and outcome. The link between CSA and PTSD symptoms was mediated by history of trauma, psychiatric history, psychological IPV, and fear of childbirth during pregnancy. Physical IPV was directly associated with postnatal PTSD symptoms, whereas psychological IPV connection seemed to be partially mediated by physical abuse and fear of childbirth during pregnancy. The role of CSA, IPV, and other psychosocial characteristics on the occurrence of PTSD symptoms following childbirth as well as the intricate network of these events should be acknowledged in clinic and intervention approaches.

  3. Geographical classification of Italian saffron (Crocus sativus L.) based on chemical constituents determined by high-performance liquid-chromatography and by using linear discriminant analysis.

    Science.gov (United States)

    D'Archivio, Angelo Antonio; Giannitto, Andrea; Maggi, Maria Anna; Ruggieri, Fabrizio

    2016-12-01

    One hundred and forty-four Italian saffron samples produced in the years from 2009 to 2015 in five distinct areas located in four different regions, Abruzzo (L'Aquila), Tuscany (Florence), Umbria (Cascia and Città della Pieve) and Sardinia, have been analysed by high-performance liquid chromatography with diode array detection. Intensities of the chromatographic peaks attributed to crocins, safranal, picrocrocin and its derivatives and flavonoids were considered as variables in linear discriminant analysis to attempt geographical classification. The results revealed that spices produced at different sites of the Italian territory can be discriminated with good accuracy. The differentiation of saffron cultivated in Sardinia from those produced in Central Italy was mainly attributed to different contents of the most abundant crocins. Good differentiation of spices produced in close sites of Central Italy was also observed, 88% of validation samples being correctly classified; some minor crocins are responsible for such discrimination.

  4. Geographical information system analysis for oceanographic parameters in the coastal waters of Goa, India - A case study

    Digital Repository Service at National Institute of Oceanography (India)

    Suryanarayana, A.; Joglekar, V.V.

    , temperature and salinity and other chemical parameters are converted to raster format. The procedure employed can be applied to other environmental management tasks like risk analysis, fishery resources etc. This paper mainly emphasis on the methodology...

  5. MULTIMEDIA ON GEOGRAPHIC NETWORK

    OpenAIRE

    Merlanti, Danilo

    2012-01-01

    In this thesis we investigate the topic of the multimedia contents distribution on a geo- graphic network which is a rarefied and huge field. First of all we have to classify the main parts necessary in the multimedia distribution on a geographic network. The main aspects of a geographic network that will be highlighted in this thesis are: the mechanism used to retrieve the sources of the multimedia content; in the case of the peer-to-peer network on geographic network one of t...

  6. People living with HIV travel farther to access healthcare: a population-based geographic analysis from rural Uganda

    Directory of Open Access Journals (Sweden)

    Adam N Akullian

    2016-02-01

    Full Text Available Introduction: The availability of specialized HIV services is limited in rural areas of sub-Saharan Africa where the need is the greatest. Where HIV services are available, people living with HIV (PLHIV must overcome large geographic, economic and social barriers to access healthcare. The objective of this study was to understand the unique barriers PLHIV face when accessing healthcare compared with those not living with HIV in a rural area of sub-Saharan Africa with limited availability of healthcare infrastructure. Methods: We conducted a population-based cross-sectional study of 447 heads of household on Bugala Island, Uganda. Multiple linear regression models were used to compare travel time, cost and distance to access healthcare, and log binomial models were used to test for associations between HIV status and access to nearby health services. Results: PLHIV travelled an additional 1.9 km (95% CI (0.6, 3.2 km, p=0.004 to access healthcare compared with those not living with HIV, and they were 56% less likely to access healthcare at the nearest health facility to their residence, so long as that facility lacked antiretroviral therapy (ART services (aRR=0.44, 95% CI (0.24 to 0.83, p=0.011. We found no evidence that PLHIV travelled further for care if the nearest facility supplies ART services (aRR=0.95, 95% CI (0.86 to 1.05, p=0.328. Among those who reported uptake of care at one of two facilities on the island that provides ART (81% of PLHIV and 68% of HIV-negative individuals, PLHIV tended to seek care at a higher tiered facility that provides ART, even when this facility was not their closest facility (30% of PLHIV travelled further than the closest ART facility compared with 16% of HIV-negative individuals, and travelled an additional 2.2 km (p=0.001 to access that facility, relative to HIV-negative individuals (aRR=1.91, 95% CI (1.00 to 3.65, p=0.05. Among PLHIV, residential distance was associated with access to facilities providing

  7. Breton Island, Louisiana Baseline (Geographic, NAD83)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Breton Island, Louisiana Baseline (Geographic, NAD83) consists of vector line data that were input into the Digital Shoreline Analysis System (DSAS) version 4.0,...

  8. GNIS: Geographic Names Information Systems - All features

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The Geographic Names Information System (GNIS) actively seeks data from and partnerships with Government agencies at all levels and other interested organizations....

  9. Systematic meta-analysis of childhood social withdrawal in schizophrenia, and comparison with data from at-risk children aged 9-14 years.

    Science.gov (United States)

    Matheson, Sandra L; Vijayan, Hena; Dickson, Hannah; Shepherd, Alana M; Carr, Vaughan J; Laurens, Kristin R

    2013-08-01

    Social withdrawal is a robust childhood risk factor for later schizophrenia. The aims of this paper were to assess the evidence for childhood social withdrawal among adults with schizophrenia and, comparatively, in children aged 9-14 years who are putatively at-risk of developing schizophrenia. We conducted a meta-analysis, including cohort and case-control studies reporting social withdrawal measured by the Child Behavior Checklist (CBCL) in adults with schizophrenia vs. controls. Further, an experimental study compared CBCL withdrawal scores from typically-developing children with scores from two groups of putatively at-risk children: (i) children displaying a triad of replicated antecedents for schizophrenia, and (ii) children with at least one first- or second-degree relative with schizophrenia or schizoaffective disorder. Six studies met inclusion criteria for the meta-analysis (N = 3828), which demonstrated a large effect of increased childhood social withdrawal in adults with schizophrenia (standardized mean difference [SMD] score = 1.035, 95% CI = 0.304-1.766, p = 0.006), with no indication of publication bias, but considerable heterogeneity (I(2) = 91%). Results from the experimental study also indicated a large effect of increased social withdrawal in children displaying the antecedent triad (SMD = 0.743, p = 0.001), and a weaker effect in children with a family history of schizophrenia (SMD = 0.442, p = 0.051). Childhood social withdrawal may constitute a vulnerability marker for schizophrenia in the presence of other antecedents and/or genetic risk factors for schizophrenia.

  10. Introduction of complementary feeding before 4months of age increases the risk of childhood overweight or obesity: a meta-analysis of prospective cohort studies.

    Science.gov (United States)

    Wang, Jing; Wu, Yuanjue; Xiong, Guoping; Chao, Tingting; Jin, Qiu; Liu, Rui; Hao, Liping; Wei, Sheng; Yang, Nianhong; Yang, Xuefeng

    2016-08-01

    The association between the age at introduction of complementary feeding and the risk of overweight or obesity during childhood has been hotly debated, but the result remains uncertain. This meta-analysis of prospective cohort studies attempted to evaluate this association, as well as provide evidence for infant feeding recommendations. The PubMed, Embase, and Cochrane databases were systematically searched for relevant original articles published prior to March 1, 2015 that met predefined inclusion criteria. The pooled relative risks (RRs) and corresponding 95% confidence intervals (CIs) were calculated using fix-effect or random-effect models, which were chosen based on heterogeneity among studies. Ten articles consisting of 13 studies, where 8 measured being overweight as an outcome and 5 measured being obese, were included in this meta-analysis. There were a total of 63,605 participants and 11,900 incident cases in the overweight studies, and 56,136 individuals and 3246 incident cases in the obese studies. The pooled results revealed that introducing complementary foods before 4months of age compared to at 4 to 6months was associated with an increased risk of being overweight (RR, 1.18; 95% CI, 1.06-1.31) or obese (RR, 1.33; 95% CI, 1.07-1.64) during childhood. No significant relationship was observed between delaying introduction of complementary foods after 6months of age, and being overweight (RR, 1.01; 95% CI, 0.90-1.13) or obese (RR, 1.02; 95% CI, 0.91-1.14) during childhood. The results of this study suggest that the introduction of complementary foods to infants before 4months of age should be avoided to protect against childhood obesity.

  11. Geographical origin of Plasmodium vivax in the Republic of Korea: haplotype network analysis based on the parasite's mitochondrial genome

    Directory of Open Access Journals (Sweden)

    Iwagami Moritoshi

    2010-06-01

    Full Text Available Abstract Background The Republic of Korea (South Korea is one of the countries where vivax malaria had been successfully eradicated by the late 1970s. However, re-emergence of vivax malaria in South Korea was reported in 1993. Several epidemiological studies and some genetic studies using antigenic molecules of Plasmodium vivax in the country have been reported, but the evolutionary history of P. vivax has not been fully understood. In this study, the origin of the South Korean P. vivax population was estimated by molecular phylogeographic analysis. Methods A haplotype network analysis based on P. vivax mitochondrial (mt DNA sequences was conducted on 11 P. vivax isolates from South Korea and another 282 P. vivax isolates collected worldwide. Results The network analysis of P. vivax mtDNA sequences showed that the coexistence of two different groups (A and B in South Korea. Groups A and B were identical or close to two different populations in southern China. Conclusions Although the direct introduction of the two P. vivax populations in South Korea were thought to have been from North Korea, the results of this analysis suggest the genealogical origin to be the two different populations in southern China.

  12. Validated HPTLC analysis method for quantification of variability in content of curcumin in Curcuma longa L (turmeric) collected from different geographical region of India

    Institute of Scientific and Technical Information of China (English)

    Kamran Ashraf; Mohd Mujeeb; Altaf Ahmad; Mohd Amir; Md Nasar Mallick; Deepak Sharma

    2012-01-01

    Objective: To develop a simple, sensitive, precise, and accurate stability-indicating high performance thin-layer chromatographic method for analysis of curcumin (the main active constituent of turmeric). Methods: The separation was achieved on TLC aluminum plates precoated with silica gel 60F254 using toluene-chloroform-methanol (5:4:1, v/v/v) as a mobile phase. Densitometric analysis was performed at 430 nm. Results: This system was found to have compact spot of curcumin at RF value of (0.31±0.02). For the proposed procedure, linearity (r2= 0.99354 ± 0.00120), limit of detection (50 ng/spot), limit of quantification (200 ng/spot), recovery (ranging from 98.35% - 100.68%), and precision (≤2.25%) were found to be satisfactory. Statistical analysis reveals that the content of curcumin in different geographical region varied significantly.Conclusions:The highest and lowest concentration of curcumin in Turmeric was found to be present in sample of Erode (Tamilnadu) and Surat (Gujrat) respectively which inferred that the variety of turmeric found in Erode (Tamilnadu) is much superior to other region of India.

  13. Characterization of the Authenticity of Pasta di Gragnano Protected Geographical Indication Through Flavor Component Analysis by Gas Chromatography-Mass Spectrometry and Chemometric Tools.

    Science.gov (United States)

    Giannetti, Vanessa; Boccacci Mariani, Maurizio; Mannino, Paola

    2016-09-01

    An authentication study based on headspace solid-phase microextraction/GC-MS was performed with a set of 60 samples representative of traditional "Pasta di Gragnano protected geographical indication (PGI)" and the most common Italian pasta brands. Multivariate chemometric tools were used to classify the samples based on the chemical information provided from 20 target flavor compounds, including Maillard reaction and lipid oxidation products. Pattern recognition by principal component analysis and linear discriminant analysis showed a natural grouping of samples according to the drying process adopted for their production (i.e., the traditional Cirillo method versus a high-temperature approach). Subsequently, soft independent modeling by class analogy (SIMCA) and unequal dispersed classes (UNEQ) were used to build class models at 95% confidence and 100% sensitivity levels (forced models) for predictive classification purposes. The good performance obtained from the models in terms of cross-validation efficiency (SIMCA, 57.01%; UNEQ, 86.60%; 100% for both forced models) highlighted that targeted analysis of flavor profiles could be used to assess the authenticity of Pasta di Gragnano PGI samples. Hence, the proposed method may help to protect Pasta di Gragnano PGI from label frauds by verifying whether samples comply with statements concerning drying process conditions as stated in the product specification.

  14. Morphological, molecular and cross-breeding analysis of geographic populations of coconut-mite associated predatory mites identified as Neoseiulus baraki: evidence for cryptic species?

    Science.gov (United States)

    Famah Sourassou, Nazer; Hanna, Rachid; Zannou, Ignace; Breeuwer, Johannes A J; de Moraes, Gilberto; Sabelis, Maurice W

    2012-05-01

    Surveys were conducted in Brazil, Benin and Tanzania to collect predatory mites as candidates for control of the coconut mite Aceria guerreronis Keifer, a serious pest of coconut fruits. At all locations surveyed, one of the most dominant predators on infested coconut fruits was identified as Neoseiulus baraki Athias-Henriot, based on morphological similarity with regard to taxonomically relevant characters. However, scrutiny of our own and published descriptions suggests that consistent morphological differences may exist between the Benin population and those from the other geographic origins. In this study, we combined three methods to assess whether these populations belong to one species or a few distinct, yet closely related species. First, multivariate analysis of 32 morphological characters showed that the Benin population differed from the other three populations. Second, DNA sequence analysis based on the mitochondrial cytochrome oxidase subunit I (COI) showed the same difference between these populations. Third, cross-breeding between populations was unsuccessful in all combinations. These data provide evidence for the existence of cryptic species. Subsequent morphological research showed that the Benin population can be distinguished from the others by a new character (not included in the multivariate analysis), viz. the number of teeth on the fixed digit of the female chelicera.

  15. Deciphering diversity in populations of various linguistic and ethnic affiliations of different geographical regions of India: analysis based on 15 microsatellite markers

    Indian Academy of Sciences (India)

    V. K. Kashyap; Richa Ashma; Sonali Gaikwad; B. N. Sarkar; R. Trivedi

    2004-04-01

    The extent of genetic polymorphism at fifteen autosomal microsatellite markers in 54 ethnically, linguistically and geographically diverse human populations of India was studied to decipher intrapopulation diversity. The parameters used to quantify intrapopulation diversity were average allele diversity, average heterozygosity, allele range (base pairs), and number of alleles. Multilocus genotype frequencies calculated for selected populations were utilized for testing conformity with the assumption of Hardy–Weinberg equilibrium. The exact test values, after Bonferroni correction, showed significant deviation amongst Gowda (vWA, Penta E); Dhangar, Satnami and Gounder (D8S1179); Hmar (FGA); Kuki and Balti (vWA) groups. Relatively low number of alleles and allelic diversity (base-pairs size) had been observed in populations of central India as compared with southern and northern regions of the country. The communities of Indo-Caucasoid ethnic origin and Indo-European linguistic family (Kshatriya of Uttar Pradesh) showed highest allelic diversity, as well as rare alleles, not reported in any other Indian populations. Analysis based on average heterozygosity was also found to be lowest among the populations of central India (0.729) and highest among the populations from north (0.777) and west (0.784) regions of the country, having Indo-Caucasoid ethnic origin and Austro-Asiatic linguistic affiliation. The maximum power of discrimination (85%–89%) had been observed at loci FGA, Penta E, D18S51 and D21S11, suggested high intrapopulation diversity in India. Genetic diversity revealed by STR markers was consistent with the known demographic histories of populations. Thus, the present study clearly demonstrated that the intrapopulation diversity is not only present at the national level, but also within smaller geographical regions of the country. This is the first attempt to understand the extent of diversity within populations of India at such a large scale at genomic

  16. Operational Automatic Remote Sensing Image Understanding Systems: Beyond Geographic Object-Based and Object-Oriented Image Analysis (GEOBIA/GEOOIA. Part 1: Introduction

    Directory of Open Access Journals (Sweden)

    Andrea Baraldi

    2012-09-01

    Full Text Available According to existing literature and despite their commercial success, state-of-the-art two-stage non-iterative geographic object-based image analysis (GEOBIA systems and three-stage iterative geographic object-oriented image analysis (GEOOIA systems, where GEOOIA/GEOBIA, remain affected by a lack of productivity, general consensus and research. To outperform the degree of automation, accuracy, efficiency, robustness, scalability and timeliness of existing GEOBIA/GEOOIA systems in compliance with the Quality Assurance Framework for Earth Observation (QA4EO guidelines, this methodological work is split into two parts. The present first paper provides a multi-disciplinary Strengths, Weaknesses, Opportunities and Threats (SWOT analysis of the GEOBIA/GEOOIA approaches that augments similar analyses proposed in recent years. In line with constraints stemming from human vision, this SWOT analysis promotes a shift of learning paradigm in the pre-attentive vision first stage of a remote sensing (RS image understanding system (RS-IUS, from sub-symbolic statistical model-based (inductive image segmentation to symbolic physical model-based (deductive image preliminary classification. Hence, a symbolic deductive pre-attentive vision first stage accomplishes image sub-symbolic segmentation and image symbolic pre-classification simultaneously. In the second part of this work a novel hybrid (combined deductive and inductive RS-IUS architecture featuring a symbolic deductive pre-attentive vision first stage is proposed and discussed in terms of: (a computational theory (system design; (b information/knowledge representation; (c algorithm design; and (d implementation. As proof-of-concept of symbolic physical model-based pre-attentive vision first stage, the spectral knowledge-based, operational, near real-time Satellite Image Automatic Mapper™ (SIAM™ is selected from existing literature. To the best of these authors’ knowledge, this is the first time a

  17. Maternal age at birth and childhood type 1 diabetes: a pooled analysis of 30 observational studies

    DEFF Research Database (Denmark)

    Cardwell, Chris R; Stene, Lars C; Joner, Geir;

    2009-01-01

    for potential confounders. Meta-analysis techniques were used to derive combined odds ratios and to investigate heterogeneity among studies. RESULTS: Data were available for 5 cohort and 25 case-control studies, including 14,724 cases of type 1 diabetes. Overall, there was, on average, a 5% (95% CI 2...

  18. Birth order and childhood type 1 diabetes risk: a pooled analysis of 31 observational studies

    DEFF Research Database (Denmark)

    Cardwell, Chris R; Stene, Lars C; Joner, Geir;

    2010-01-01

    of previous studies. METHODS: Relevant studies published before January 2010 were identified from MEDLINE, Web of Science and EMBASE. Authors of studies provided individual patient data or conducted pre-specified analyses. Meta-analysis techniques were used to derive combined odds ratios (ORs), before...

  19. A Cross-Sectional Behavioral Genetic Analysis of Task Persistence in the Transition to Middle Childhood

    Science.gov (United States)

    Deater-Deckard, Kirby; Petrill, Stephen A.; Thompson, Lee A.; DeThorne, Laura S.

    2005-01-01

    Task persistence, measured by a composite score of independent teacher, tester and observer reports, was examined using behavioral genetic analysis. Participants included 92 monozygotic and 137 same-sex dizygotic twin pairs in Kindergarten or 1st grade (4.3 to 7.9 years old). Task persistence was widely distributed, higher among older children,…

  20. The spatial analysis on hemorrhagic fever with renal syndrome in Jiangsu province, China based on geographic information system.

    Directory of Open Access Journals (Sweden)

    Changjun Bao

    Full Text Available Hemorrhagic fever with renal syndrome (HFRS is endemic in mainland China, accounting for 90% of total reported cases worldwide, and Jiangsu is one of the most severely affected provinces. In this study, the authors conducted GIS-based spatial analyses in order to determine the spatial distribution of the HFRS cases, identify key areas and explore risk factors for public health planning and resource allocation.Interpolation maps by inverse distance weighting were produced to detect the spatial distribution of HFRS cases in Jiangsu from 2001 to 2011. Spatio-temporal clustering was applied to identify clusters at the county level. Spatial correlation analysis was conducted to detect influencing factors of HFRS in Jiangsu.HFRS cases in Jiangsu from 2001 to 2011 were mapped and the results suggested that cases in Jiangsu were not distributed randomly. Cases were mainly distributed in northeastern and southwestern Jiangsu, especially in Dafeng and Sihong counties. It was notable that prior to this study, Sihong county had rarely been reported as a high-risk area of HFRS. With the maximum spatial size of 50% of the total population and the maximum temporal size of 50% of the total population, spatio-temporal clustering showed that there was one most likely cluster (LLR = 624.52, P<0.0001, RR = 8.19 and one second-most likely cluster (LLR = 553.97, P<0.0001, RR = 8.25, and both of these clusters appeared from 2001 to 2004. Spatial correlation analysis showed that the incidence of HFRS in Jiangsu was influenced by distances to highways, railways, rivers and lakes.The application of GIS together with spatial interpolation, spatio-temporal clustering and spatial correlation analysis can effectively identify high-risk areas and factors influencing HFRS incidence to lay a foundation for researching its pathogenesis.

  1. Identifying Distinct Geographic Health Service Environments in British Columbia, Canada: Cluster Analysis of Population-Based Administrative Data.

    Science.gov (United States)

    Lavergne, M Ruth

    2016-08-01

    Definitions of "urban" and "rural" developed for general purposes may not reflect the organization and delivery of healthcare. This research used cluster analysis to group Local Health Areas based on the distribution of healthcare spending across service categories. Though total spending was similar, the metropolitan areas of Vancouver and Victoria were identified as distinct from non-metropolitan and remote communities, based on the distribution of healthcare spending alone. Non-metropolitan communities with large community hospitals and greater physician supply were further distinguished from those with fewer healthcare resources. This approach may be useful to other researchers and service planners.

  2. GWR-PM - Spatial variation relationship analysis with Geographically Weighted Regression (GWR) - An application at Peninsular Malaysia

    Science.gov (United States)

    Jamhuri, J.; Azhar, B. M. S.; Puan, C. L.; Norizah, K.

    2016-06-01

    GWR-PM has been developed exclusively for decision makers in Peninsular Malaysia and the purpose is to provide them with additional flexibility in analysing spatial variation. While GWR extension analysis in ArcMap application has a universal coordinate system, GWR-PM is specifically designed with Peninsular Malaysia's coordinate system of Kertau RSO Malaya Meter. This paper presents the development of GWR-PM model by using a model builder, the application of which is to examine the forest fire risk at North Selangor Peat Swamp Forest. This model can be extended and improved by using ArcGIS language of phyton.

  3. Characterization of Botanical and Geographical Origin of Corsican “Spring” Honeys by Melissopalynological and Volatile Analysis

    Directory of Open Access Journals (Sweden)

    Yin Yang

    2014-01-01

    Full Text Available Pollen spectrum, physicochemical parameters and volatile fraction of Corsican “spring” honeys were investigated with the aim of developing a multidisciplinary method for the qualification of honeys in which nectar resources are under-represented in the pollen spectrum. Forty-one Corsican “spring” honeys were certified by melissopalynological analysis using directory and biogeographical origin of 50 representative taxa. Two groups of honeys were distinguished according to the botanical origin of samples: “clementine” honeys characterized by the association of cultivated species from oriental plain and other “spring” honeys dominated by wild herbaceous taxa from the ruderal and/or maquis area. The main compounds of the “spring” honey volatile fraction were phenylacetaldehyde, benzaldehyde and methyl-benzene. The volatile composition of “clementine” honeys was also characterized by three lilac aldehyde isomers. Statistical analysis of melissopalynological, physicochemical and volatile data showed that the presence of Citrus pollen in “clementine” honeys was positively correlated with the amount of linalool derivatives and methyl anthranilate. Otherwise, the other “spring” honeys were characterized by complex nectariferous species associations and the content of phenylacetaldehyde and methyl syringate.

  4. Impact of maternal obesity on inhaled corticosteroid use in childhood: a registry based analysis of first born children and a sibling pair analysis.

    Directory of Open Access Journals (Sweden)

    Adrian J Lowe

    Full Text Available BACKGROUND: It has been proposed that maternal obesity during pregnancy may increase the risk that the child develops allergic disease and asthma, although the mechanisms underpinning this relationship are currently unclear. We sought to assess if this association may be due to confounding by genetic or environmental risk factors that are common to maternal obesity and childhood asthma, using a sibling pair analysis. METHODS: The study population comprised a Swedish national cohort of term children born between 1992 and 2008 to native Swedish parents. Maternal body mass index (BMI was measured at 8-10 weeks gestation. Unconditional logistic regression models were used to determine if maternal obesity was associated with increased risk of inhaled corticosteroid (ICS in 431,718 first-born children, while adjusting for potential confounders. An age-matched discordant sib-pair analysis was performed, taking into account shared genetic and environmental risk factors. RESULTS: Maternal over-weight and obesity were associated with increased risk that the child would require ICS (for BMI≥35 kg/m(2, aOR = 1.30, 95%CI = 1.10-1.52 compared with normal weight mothers in children aged 6-12 years. Similar effects were seen in younger children, but in children aged 13-16 years, maternal obesity (BMI≥30 was related to increased risk of ICS use in girls (aOR = 1.28, 95%CI = 1.07-1.53 but not boys (OR = 1.05, 95%CI = 0.87-1.26. The sib-pair analysis, which included 2,034 sib-pairs older than six years who were discordant for both ICS use and maternal BMI category, failed to find any evidence that increasing maternal weight was related to increased risk of ICS use. CONCLUSION: Maternal obesity is associated with increased risk of childhood ICS use up to approximately 12 years of age, but only in girls after this age. These effects could not be confirmed in a sib pair analysis, suggesting either limited statistical power, or the effects

  5. Statistical and Multidimensional Body Composition Parameter Analysis in Young Childhood Cancer Survivors

    Directory of Open Access Journals (Sweden)

    Topczewska Magdalena

    2014-12-01

    Full Text Available This article concerns the problem of assessing selected body compo- sition parameters after completion of antitumor therapy and comparing them with the same parameters of healthy children. A high percentage of overweight and obesity, as well as abnormal fat distribution in convalescents with cancer shows a significant adverse effect of therapy on body composition and suggests the need for early intervention in terms of diet and exercise, which would help patients to quickly achieve the proper parameters of body composition. Two main problems will be mentioned during the presented data analysis. Firstly, in each group there was a small number of observations. Because of this, the real differences between examined subgroups may have been omitted. Secondarily, many variables are correlated and are not normally distributed. Therefore, be- side the standard statistical tests to compare two groups, principal component analysis was applied to reduce the dimensions of the attribute space and to attempt to classify two groups of patients.

  6. Dimensional Analysis of Psychosocial Barriers to Prevention of Early Childhood Caries Among Recent Immigrants

    Directory of Open Access Journals (Sweden)

    Arnaldo Perez

    2014-06-01

    Full Text Available The objective of this article is to define the underlying dimensions of psychosocial barriers to obtaining and providing dental care for young children among recent immigrants. Fifteen focus groups were conducted with 99 primary caregivers from African, South Asian, and Chinese recent immigrants. A secondary analysis of identified barriers using dimensional analysis methodology was performed to determine dimensions and properties of barriers. The analysis continued until irreducible properties were found or emerging dimensions were not relevant to the study. Identified dimensions were associated with barriers and individuals. Type, number, level, objectiveness, nature, and impact were barrier-related; awareness and controllability were individual-related dimensions. Type refers to barriers themselves. Number and level indicate the amount and location of barriers, respectively. Objectiveness refers to the extent that perceived barrier reflects reality and nature indicates its intrinsic characteristic. Impact concerns behaviors, goals, and outcomes compromised by barriers. Awareness alludes to the extent that individuals are aware of the barriers and controllability explains how much control people perceive to have over barriers. Identified dimensions are useful for better understanding and addressing existing barriers to children’s optimal oral health.

  7. Systematic review and meta-analysis investigating breast feeding and childhood wheezing illness.

    Science.gov (United States)

    Brew, Bronwyn K; Allen, C Wendy; Toelle, Brett G; Marks, Guy B

    2011-11-01

    There is conflicting evidence concerning the relationship between breast feeding and wheezing illness. The objective of this study was to investigate whether there is any association between breast feeding and wheezing in children aged over 5 years and to discover possible sources of heterogeneity. An electronic search of MEDLINE and EMBASE databases was conducted from January 2000 to June 2010. In addition, reference lists from relevant publications were searched. Birth cohort, cross-sectional and case-control studies were included if they measured any breast feeding or exclusive breast feeding for 3 or 4 months. Wheezing illness, including asthma, was identified based on symptoms, reported diagnosis or objective criteria. Thirty-one publications were identified for meta-analysis. There was no association found between any or exclusive breast feeding and wheezing illness, although there was a high level of heterogeneity between the studies. Subgroup analysis revealed that any breast feeding slightly lowers the odds of wheeze (pooled odds ratio 0.92 [0.86, 0.98]) but slightly increases the odds of asthma defined by specific criteria (pooled odds ratio 1.10 [1.00, 1.22]). This meta-analysis does not provide evidence that breast feeding is protective against wheezing illness in children aged 5 years and over. The difference in the effects of breast feeding according to the nature of the wheezing illness highlights the importance of the heterogeneity of illness phenotypes.

  8. Analysis of childhood leukemia mortality trends in Brazil, from 1980 to 2010

    Directory of Open Access Journals (Sweden)

    Franciane F. Silva

    2014-12-01

    Full Text Available OBJECTIVE: Leukemias comprise the most common group of cancers in children and adolescents. Studies conducted in other countries and Brazil have observed a decrease in their mortality.This study aimed to evaluate the trend of mortality from leukemia in children under 19 years of age in Brazil, from 1980 to 2010. METHODS: This was an ecological study, using retrospective time series data from the Mortality Information System, from 1980 to 2010. Calculations of mortality rates were performed, including gross, gender-specific, and age-based. For trend analysis, linear and semi-log regression models were used. The significance level was 5%. RESULTS: Mortality rates for lymphoid and myeloid leukemias presented a growth trend, with the exception of lymphoid leukemia among children under 4 years of age (percentage decrease: 1.21% annually, while in the sub-group "Other types of leukemia", a downward trend was observed. Overall, mortality from leukemia tended to increase for boys and girls, especially in the age groups 10-14 years (annual percentage increase of 1.23% for males and 1.28% for females and 15-19 years (annual percentage increase of 1.40% for males and 1.62% for females. CONCLUSIONS: The results for leukemia generally corroborate the results of other similar studies. A detailed analysis by subgroup of leukemia, age, and gender revealed no trends shown in other studies, thus indicating special requirements for each variable in the analysis.

  9. Analysis of risk factors of childhood bronchial asthma%儿童支气管哮喘发病的危险因素分析

    Institute of Scientific and Technical Information of China (English)

    彭桂英

    2014-01-01

    Objective To investigate and analyze the risk factors of childhood bronchial asthma. Methods 176 children with bronchial asthma treated in our hospital were selected as the asthma group and 176 normal children in the corresponding period were selected as the normal group in the same time. First, SPSS17.0 was used to conduct univariate analysis on 17 pathogenic factors of childhood bronchial asthma and the screened out single factors with P < 0.05 served as the independent variables of Logistic regression model for multivariate analysis. Then the high risk factors of childhood bronchial asthma were obtained. Results Univariate analysis showed that there were 10 single factors influencing childhood bronchial asthma, with statistically significant differences to the normal group (P<0.05). Logistic multivariate regression analysis showed that the high risk factors of childhood bronchial asthma were respiratory tract infection, family history of asthma,non-supplement of cod liver oil and family smoking and the protective factor of asthma was breastfeeding. Conclusion Preventing high risk factors of childhood bronchial asthma actively and increasing protective awareness are of important significance to the prevention and control of childhood bronchial asthma.%目的:探讨儿童支气管哮喘发病的危险因素。方法选取就诊于我院的儿童支气管患儿176例纳入哮喘组,同时选取同期正常儿童176例纳入正常组。首先采用SPSS17.0作单因素分析可能引起儿童支气管哮喘的发病因素17项,筛选出P<0.05的单因素作Logistic回归模型的自变量,作多因素分析,得出影响儿童支气管哮喘的高危因素。结果经单因素分析结果显示,影响儿童支气管哮喘的单因素共有10项,且P<0.05,与正常组对比具有统计学意义。Logistic多因素回归分析结果显示,影响儿童支气管哮喘的高危因素为呼吸道感染、家族哮喘史、未补充鱼肝油、家人

  10. Analysis of genetic diversity of Brassica rapa var. chinensis using ISSR markers and development of SCAR marker specific for Fragrant Bok Choy, a product of geographic indication.

    Science.gov (United States)

    Shen, X L; Zhang, Y M; Xue, J Y; Li, M M; Lin, Y B; Sun, X Q; Hang, Y Y

    2016-04-25

    Non-heading Chinese cabbage [Brassica rapa var. chinensis (Linnaeus) Kitamura] is a popular vegetable and is also used as a medicinal plant in traditional Chinese medicine. Fragrant Bok Choy is a unique accession of non-heading Chinese cabbage and a product of geographic indication certified by the Ministry of Agriculture of China, which is noted for its rich aromatic flavor. However, transitional and overlapping morphological traits can make it difficult to distinguish this accession from other non-heading Chinese cabbages. This study aimed to develop a molecular method for efficient identification of Fragrant Bok Choy. Genetic diversity analysis, based on inter-simple sequence repeat molecular markers, was conducted for 11 non-heading Chinese cabbage accessions grown in the Yangtze River Delta region. Genetic similarity coefficients between the 11 accessions ranged from 0.5455 to 0.8961, and the genetic distance ranged from 0.0755 to 0.4475. Cluster analysis divided the 11 accessions into two major groups. The primer ISSR-840 amplified a fragment specific for Fragrant Bok Choy. A pair of specific sequence-characterized amplified region (SCAR) primers based on this fragment amplified a target band in Fragrant Bok Choy individuals, but no band was detected in individuals of other accessions. In conclusion, this study has developed an efficient strategy for authentication of Fragrant Bok Choy. The SCAR marker described here will facilitate the conservation and utilization of this unique non-heading Chinese cabbage germplasm resource.

  11. Training set size, scale, and features in Geographic Object-Based Image Analysis of very high resolution unmanned aerial vehicle imagery

    Science.gov (United States)

    Ma, Lei; Cheng, Liang; Li, Manchun; Liu, Yongxue; Ma, Xiaoxue

    2015-04-01

    Unmanned Aerial Vehicle (UAV) has been used increasingly for natural resource applications in recent years due to their greater availability and the miniaturization of sensors. In addition, Geographic Object-Based Image Analysis (GEOBIA) has received more attention as a novel paradigm for remote sensing earth observation data. However, GEOBIA generates some new problems compared with pixel-based methods. In this study, we developed a strategy for the semi-automatic optimization of object-based classification, which involves an area-based accuracy assessment that analyzes the relationship between scale and the training set size. We found that the Overall Accuracy (OA) increased as the training set ratio (proportion of the segmented objects used for training) increased when the Segmentation Scale Parameter (SSP) was fixed. The OA increased more slowly as the training set ratio became larger and a similar rule was obtained according to the pixel-based image analysis. The OA decreased as the SSP increased when the training set ratio was fixed. Consequently, the SSP should not be too large during classification using a small training set ratio. By contrast, a large training set ratio is required if classification is performed using a high SSP. In addition, we suggest that the optimal SSP for each class has a high positive correlation with the mean area obtained by manual interpretation, which can be summarized by a linear correlation equation. We expect that these results will be applicable to UAV imagery classification to determine the optimal SSP for each class.

  12. Geographic Object-Based Image Analysis Using Optical Satellite Imagery and GIS Data for the Detection of Mining Sites in the Democratic Republic of the Congo

    Directory of Open Access Journals (Sweden)

    Fritjof Luethje

    2014-07-01

    Full Text Available Earth observation is an important source of information in areas that are too remote, too insecure or even both for traditional field surveys. A multi-scale analysis approach is developed to monitor the Kivu provinces in the Democratic Republic of the Congo (DRC to identify hot spots of mining activities and provide reliable information about the situation in and around two selected mining sites, Mumba-Bibatama and Bisie. The first is the test case for the approach and the detection of unknown mining sites, whereas the second acts as reference case since it is the largest and most well-known location for cassiterite extraction in eastern Congo. Thus it plays a key-role within the context of the conflicts in this region. Detailed multi-temporal analyses of very high-resolution (VHR satellite data demonstrates the capabilities of Geographic Object-Based Image Analysis (GEOBIA techniques for providing information about the situation during a mining ban announced by the Congolese President between September 2010 and March 2011. Although the opening of new surface patches can serve as an indication for activities in the area, the pure change between the two satellite images does not in itself produce confirming evidence. However, in combination with observations on the ground, it becomes evident that mining activities continued in Bisie during the ban, even though the production volume went down considerably.

  13. Mourning a Lost Childhood: A Therapeutic Task.

    Science.gov (United States)

    Kulish, Nancy Mann

    J. M. Barrie's popular story of Peter Pan depicts the never-neverland of an endless happy childhood. Analysis of the story and of J. M. Barrie's personal background, however, reveals that the tale is a conflicted solution to and separation from early childhood losses and disappointments. Themes of separation and reunion, redesertion and revenge…

  14. Risk Factors Associated with Renal Involvement in Childhood Henoch-Schönlein Purpura: A Meta-Analysis

    Science.gov (United States)

    Chan, Han; Tang, Yan-Ling; Lv, Xiao-Hang; Zhang, Gao-Fu; Wang, Mo; Yang, Hai-Ping; Li, Qiu

    2016-01-01

    Background and objective Henoch-Schönlein purpura (HSP) is an important cause of chronic kidney disease in children. This meta-analysis identified risk factors associated with renal involvement in childhood HSP. Methods PubMed, Embase, and Web of Science were searched. The quality of all eligible studies was assessed using the Newcastle-Ottawa scale criteria. An analysis of possible risk factors was conducted to report the odds ratio (OR) and weighted mean difference (WMD). Results Thirteen studies (2398 children) revealed 20 possible and 13 significant risk factors associated with renal involvement in HSP, with the following meta-analysis estimates of OR and WMD, with 95% confidence intervals: older age (0.90, 0.61–1.19); age > 10 y (3.13, 1.39–7.07); male gender (1.36, 1.07–1.74); abdominal pain (1.94,1.24–3.04); gastrointestinal bleeding (1.86, 1.30–2.65); severe bowel angina (3.38, 1.17–9.80); persistent purpura (4.02, 1.22–13.25); relapse (4.70, 2.42–9.14); WBC > 15 × 109/L (2.42, 1.39–4.22); platelets > 500 × 109/L (2.98, 1.22–7.25); elevated antistreptolysin O (ASO) (2.17, 1.29–3.64); and decreased complement component 3 (C3) (3.13, 1.62–6.05). Factors not significantly associated with renal involvement were: blood pressure; orchitis; elevated C-reactive protein; elevated erythrocyte sedimentation rate (ESR); and elevated serum IgA/IgE or IgG. Arthritis/arthralgia may be a risk factor according to the criteria of the American College of Rheumatology (1.41, 1.01–1.96). Conclusion The following are associated with renal involvement in pediatric HSP: male gender; > 10 y old; severe gastrointestinal symptoms (abdominal pain, gastrointestinal bleeding, and severe bowel angina); arthritis/arthralgia; persistent purpura or relapse; WBC > 15 × 109/L; platelets > 500 × 109/L; elevated ASO; and low C3. Relevant clinical interventions for these risk factors may exert positive effects on the prevention of kidney disease during the early

  15. Consequences of bullying victimization in childhood and adolescence: A systematic review and meta-analysis

    Science.gov (United States)

    Moore, Sophie E; Norman, Rosana E; Suetani, Shuichi; Thomas, Hannah J; Sly, Peter D; Scott, James G

    2017-01-01

    AIM To identify health and psychosocial problems associated with bullying victimization and conduct a meta-analysis summarizing the causal evidence. METHODS A systematic review was conducted using PubMed, EMBASE, ERIC and PsycINFO electronic databases up to 28 February 2015. The study included published longitudinal and cross-sectional articles that examined health and psychosocial consequences of bullying victimization. All meta-analyses were based on quality-effects models. Evidence for causality was assessed using Bradford Hill criteria and the grading system developed by the World Cancer Research Fund. RESULTS Out of 317 articles assessed for eligibility, 165 satisfied the predetermined inclusion criteria for meta-analysis. Statistically significant associations were observed between bullying victimization and a wide range of adverse health and psychosocial problems. The evidence was strongest for causal associations between bullying victimization and mental health problems such as depression, anxiety, poor general health and suicidal ideation and behaviours. Probable causal associations existed between bullying victimization and tobacco and illicit drug use. CONCLUSION Strong evidence exists for a causal relationship between bullying victimization, mental health problems and substance use. Evidence also exists for associations between bullying victimization and other adverse health and psychosocial problems, however, there is insufficient evidence to conclude causality. The strong evidence that bullying victimization is causative of mental illness highlights the need for schools to implement effective interventions to address bullying behaviours.

  16. MR volumetric analysis of the course of nephroblastomatosis under chemotherapy in childhood

    Energy Technology Data Exchange (ETDEWEB)

    Guenther, Patrick; Waag, Karl Ludwig [Department of Paediatric Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg (Germany); Troeger, Jochen; Schenk, Jens-Peter [Department of Paediatric Radiology, University of Heidelberg (Germany); Graf, Norbert [Department of Paediatric Oncology, Children' s Hospital, University of Homburg/Saar (Germany)

    2004-08-01

    Nephroblastomatosis is a paediatric renal disease that may undergo malignant transformation. When neoadjuvant chemotherapy is indicated for nephroblastomatosis or bilateral Wilms' tumours, exact volumetric analysis using high-speed data processing and visualization may aid in determining tumour response. Using 3D-volume-rendering software, the 0.5-T MRI data of a 2-year-old girl with bilateral nephroblastomatosis was analysed. Exact volume determination of foci of nephroblastomatosis was performed by automatic and manual segmentation, and the relation to normal renal parenchyma was determined over a 12-month period. At the first visit, 80% (460/547 ml) of the extremely enlarged right kidney was due to nephroblastomatosis. Total tumour volume within the right kidney decreased to 74 ml under chemotherapy. Volume analysis of the two emerging right-sided masses after treatment correctly suggested Wilms' tumour. Three-dimensional rendering of the growing masses aided the surgeon in nephron-sparing surgery during tumour resection. (orig.)

  17. Analysis of single nucleotide polymorphisms based on RNA sequencing data of diverse bio-geographical accessions in barley

    Science.gov (United States)

    Takahagi, Kotaro; Uehara-Yamaguchi, Yukiko; Yoshida, Takuhiro; Sakurai, Tetsuya; Shinozaki, Kazuo; Mochida, Keiichi; Saisho, Daisuke

    2016-01-01

    Barley is one of the founder crops of Old world agriculture and has become the fourth most important cereal worldwide. Information on genome-scale DNA polymorphisms allows elucidating the evolutionary history behind domestication, as well as discovering and isolating useful genes for molecular breeding. Deep transcriptome sequencing enables the exploration of sequence variations in transcribed sequences; such analysis is particularly useful for species with large and complex genomes, such as barley. In this study, we performed RNA sequencing of 20 barley accessions, comprising representatives of several biogeographic regions and a wild ancestor. We identified 38,729 to 79,949 SNPs in the 19 domesticated accessions and 55,403 SNPs in the wild barley and revealed their genome-wide distribution using a reference genome. Genome-scale comparisons among accessions showed a clear differentiation between oriental and occidental barley populations. The results based on population structure analyses provide genome-scale properties of sub-populations grouped to oriental, occidental and marginal groups in barley. Our findings suggest that the oriental population of domesticated barley has genomic variations distinct from those in occidental groups, which might have contributed to barley’s domestication. PMID:27616653

  18. Variations of pterygium prevalence by age, gender and geographic characteristics in China: A systematic review and meta-analysis

    Science.gov (United States)

    Song, Peige; Chang, Xinlei; Wang, Manli

    2017-01-01

    Background Pterygium is a common chronic ophthalmic condition, which may result in significant visual morbidity or lead to blindness in extreme cases. The prevalence of pterygium in China has not been reported at the sub-national level. Methods In this study, we conducted a systematic review and meta-analysis to estimate the prevalence of pterygium in China. China National Knowledge Infrastructure (CNKI), Wanfang, Chinese Biomedicine Literature Database (CBM-SinoMed), PubMed, Embase and Medline were searched before September 2016. We performed a multilevel mixed-effect meta-regression based on the included studies, our results showed that age, gender and latitude were significantly associated with pterygium prevalence. Based on the final model, the age and gender-specific prevalence of pterygium in 31 Chinese provinces (except Hongkong, Macau and Taiwan) and the whole country was generated. Results In 2010, the overall prevalence of pterygium in Chinese people aged 15–84 years was 9.84% (95% CI: 6.72–14.14), and the number of pterygium cases in China was 108.65 million (95% CI: 74.23–156.13). Conclusions In conclusion, the prevalence of pterygium in Chinese population in 2010 was estimated at both the national and provincial levels. The higher burden of pterygium across the country calls for efforts to advocate public health education encouraging people to take appropriate protective measures. PMID:28355301

  19. Multivariate class modeling techniques applied to multielement analysis for the verification of the geographical origin of chili pepper.

    Science.gov (United States)

    Naccarato, Attilio; Furia, Emilia; Sindona, Giovanni; Tagarelli, Antonio

    2016-09-01

    Four class-modeling techniques (soft independent modeling of class analogy (SIMCA), unequal dispersed classes (UNEQ), potential functions (PF), and multivariate range modeling (MRM)) were applied to multielement distribution to build chemometric models able to authenticate chili pepper samples grown in Calabria respect to those grown outside of Calabria. The multivariate techniques were applied by considering both all the variables (32 elements, Al, As, Ba, Ca, Cd, Ce, Co, Cr, Cs, Cu, Dy, Fe, Ga, La, Li, Mg, Mn, Na, Nd, Ni, Pb, Pr, Rb, Sc, Se, Sr, Tl, Tm, V, Y, Yb, Zn) and variables selected by means of stepwise linear discriminant analysis (S-LDA). In the first case, satisfactory and comparable results in terms of CV efficiency are obtained with the use of SIMCA and MRM (82.3 and 83.2% respectively), whereas MRM performs better than SIMCA in terms of forced model efficiency (96.5%). The selection of variables by S-LDA permitted to build models characterized, in general, by a higher efficiency. MRM provided again the best results for CV efficiency (87.7% with an effective balance of sensitivity and specificity) as well as forced model efficiency (96.5%).

  20. Trends in childhood disease.

    Science.gov (United States)

    Pallapies, Dirk

    2006-09-28

    Child mortality has declined remarkably during the last decades. While neonatal disorders, diarrhoea, pneumonia, and malaria as well as being underweight account for most of the child deaths worldwide, children's health discussions in Europe and the USA focus on other issues such as asthma, neurodevelopmental disorders, male genital malformations, and childhood cancer. There is clear evidence of increasing rates of asthma in various countries during the last decades, although rates in some countries may now have stabilised or even decline as recent UK data indicate. Although an increase in the frequency of neurodevelopmental disorders such as autism and attention deficit disorder has frequently been discussed, the limited data in this field does not justify such a conclusion. While geographic heterogeneity regarding reproductive outcomes is apparent, global trends have not been identified. Interpretation of the available information on asthma, neurodevelopmental disorders and reproductive outcomes is hampered by inconstant diagnostic criteria over place and time and the lack of good and comprehensive population-based surveillance data, which makes it impossible to ascertain trends in actual disease frequency. Data indicate that developed countries have a gradually increasing incidence in leukaemia with a corresponding drop in the incidence of lymphoma. Increases in brain tumour frequency may be related to the development and wide application of new diagnostic capabilities, rather than a true change in the incidence of malignant disease. With a better prognosis for childhood cancer survival, secondary cancers following chemotherapy appear to be increasing. A wide range of environmental factors is thought to have an impact on children's health. These factors include nutrition (protein, vitamins, antioxidants), lifestyle and behaviour choices such as tobacco and alcohol use, parental health, socio-economic status, choice of living environment (urban versus rural, etc

  1. [Early childhood handicaps in French Guyana: an analysis of relationships between families and professionals].

    Science.gov (United States)

    Gallibour, Eric

    2007-01-01

    The author reiterates that the transfer of public health policies to French Guyana has still not been able to fill in the gap related to delays in development of infrastructure and the lack of personnel in the social and medical establishments. The system of management for handicapped children in this French county is strongly influenced by the increasing immigrant population and by the vulnerability and instability of the administrative and socioeconomic situations of those families. Furthermore, the obstacles that the professionals from the socio-medical sector must confront in their daily practice and activities are described. An analysis of their portrayals and practices permit the author to show and outline their relationships with the immigrant families who are at risk, particularly that of maintaining and suffering from the general air of stigma to which they are objected to in the Guyanese society.

  2. A Cost-Benefit Analysis of Early Childhood Hygiene Interventions in Uzbekistan

    Directory of Open Access Journals (Sweden)

    Raushan ATANIYAZOVA

    2014-11-01

    Full Text Available This paper applies cost-benefit analysis (CBA technique to estimate the effectiveness of hand hygiene and oral health interventions in Uzbekistan for children of kindergarten age (3-6 years old. Our primary objective in this study is to apply CBA framework to investigate economic viability of hand hygiene and oral health interventions on respiratory diseases (influenza, bronchitis, pneumonia, intestinal diseases (diarrhea, hepatitis A, and helminthiasis, and dental caries and stomatitis. Though it is often difficult to attribute a specific hygiene intervention to a reduction in specific illness, our study shows that prevention of disease through hygiene promotion is cost-effective. To be the most effective, however, hygiene interventions should be accompanied by education and awareness-raising of teachers, parents and children.

  3. An explorative childhood pneumonia analysis based on ultrasonic imaging texture features

    Science.gov (United States)

    Zenteno, Omar; Diaz, Kristians; Lavarello, Roberto; Zimic, Mirko; Correa, Malena; Mayta, Holger; Anticona, Cynthia; Pajuelo, Monica; Oberhelman, Richard; Checkley, William; Gilman, Robert H.; Figueroa, Dante; Castañeda, Benjamín.

    2015-12-01

    According to World Health Organization, pneumonia is the respiratory disease with the highest pediatric mortality rate accounting for 15% of all deaths of children under 5 years old worldwide. The diagnosis of pneumonia is commonly made by clinical criteria with support from ancillary studies and also laboratory findings. Chest imaging is commonly done with chest X-rays and occasionally with a chest CT scan. Lung ultrasound is a promising alternative for chest imaging; however, interpretation is subjective and requires adequate training. In the present work, a two-class classification algorithm based on four Gray-level co-occurrence matrix texture features (i.e., Contrast, Correlation, Energy and Homogeneity) extracted from lung ultrasound images from children aged between six months and five years is presented. Ultrasound data was collected using a L14-5/38 linear transducer. The data consisted of 22 positive- and 68 negative-diagnosed B-mode cine-loops selected by a medical expert and captured in the facilities of the Instituto Nacional de Salud del Niño (Lima, Peru), for a total number of 90 videos obtained from twelve children diagnosed with pneumonia. The classification capacity of each feature was explored independently and the optimal threshold was selected by a receiver operator characteristic (ROC) curve analysis. In addition, a principal component analysis was performed to evaluate the combined performance of all the features. Contrast and correlation resulted the two more significant features. The classification performance of these two features by principal components was evaluated. The results revealed 82% sensitivity, 76% specificity, 78% accuracy and 0.85 area under the ROC.

  4. 选择电力地理信息系统平台的分析%Analysis of Choosing the Platform in Power Geographic Information System

    Institute of Scientific and Technical Information of China (English)

    刘理峰; 孙才新; 周泉; 金学军; 李小平

    2001-01-01

    Geographic Information System(GIS) is playing more and more important role in information management of power system. The popular GIS platform products include GeoMedia, Arc/Info, MapInfo and MicroStation. The choosing and using of power GIS platform should obey the rule in power system reality. Based on their preponderant application in geographic industry, Arc/Info and MapInfo have been successfully used in power system. The scheme of power GIS platform is put forward in this paper, referenced to the judgement and analysis of these prevailing platform, and the example of "GIS information system in Chongqing YuBei Power Supply Bureau" is given. This example shows the powerful twice developing ability, the profound network topology analysis ability of this method, which could also satisfy the needs of excessive and separate work nodes and parallel operation. All researches showed in this paper demonstrate the method could satisfy the need of power GIS.%地理信息系统(GIS)在电力系统信息管理中起着越来越重要的作用。目前GIS平台主要有GeoMedia、Arc/Info、MapInfo和MicroStation四种产品。电力GIS平台的选择和使用必须从电力系统实际出发,借助于各自在地理行业的优势,Arc/Info和MapInfo产品已成功进入电力市场。通过对目前几种GIS通用平台的深入比较、分析,提出了一种基于GeoMedia的电力GIS平台解决方案,并介绍了该平台方案在“重庆渝北供电局GIS综合信息系统”中的应用。应用表明该方案具有强大的二次开发能力,满足工作节点多且分散、并发操作强的要求,具有良好的网络拓扑分析功能,能够满足电力GIS的要求。

  5. The Concept of Happiness as Conveyed in Visual Representations: Analysis of the Work of Early Childhood Educators

    Science.gov (United States)

    Russo-Zimet, Gila; Segel, Sarit

    2014-01-01

    This research was designed to examine how early-childhood educators pursuing their graduate degrees perceive the concept of happiness, as conveyed in visual representations. The research methodology combines qualitative and quantitative paradigms using the metaphoric collage, a tool used to analyze visual and verbal aspects. The research…

  6. Childhood Trauma in Substance Use Disorder and Depression: An Analysis by Gender among a Brazilian Clinical Sample

    Science.gov (United States)

    Tucci, Adriana M.; Kerr-Correa, Florence; Souza-Formigoni, Maria Lucia O.

    2010-01-01

    Objective: In this study, we compared the frequency and intensity of childhood traumas in alcohol- or other drug-dependent patients, in patients with depression, and in a control group without psychiatric diagnoses. Methods: The study had a retrospective design of a clinical sample of men and women from the groups listed above. They were evaluated…

  7. An Analysis of Bronfenbrenner's Bio-Ecological Perspective for Early Childhood Educators: Implications for Working with Families Experiencing Stress

    Science.gov (United States)

    Swick, Kevin James; Williams, Reginald D.

    2006-01-01

    Today's families face many stressors during the early childhood years. Particular stressors like homelessness, violence, and chemical dependence, play havoc with the family system. Urie Bronfenbrenner's bio-ecological perspective offers an insightful lens for understanding and supporting families under stress. This article presents the key…

  8. Brain Development of Very Preterm and Very Low-Birthweight Children in Childhood and Adolescence: A Meta-Analysis

    Science.gov (United States)

    de Kieviet, Jorrit F.; Zoetebier, Lydia; van Elburg, Ruurd M.; Vermeulen, R. Jeroen; Oosterlaan, Jaap

    2012-01-01

    Aim: The aim of this article was to clarify the impact and consequences of very preterm birth (born less than 32wks of gestation) and/or very low birthweight ([VLBW], weighing less than 1500g) on brain volume development throughout childhood and adolescence. Method: The computerized databases PubMed, Web of Knowledge, and EMBASE were searched for…

  9. Geographic Variation in Cancer Incidence among Children and Adolescents in Taiwan (1995-2009.

    Directory of Open Access Journals (Sweden)

    Giun-Yi Hung

    Full Text Available Evidence from our recent study suggested that the overall trend for cancer incidence in children and adolescents has been increasing in Taiwan.To analyze geographic variations in this trend, cancer frequencies and incidence rates of disease groups were quantified according to geographic areas among 12,633 patients aged <20 years during 1995-2009 by using the population-based Taiwan Cancer Registry. Three geographic levels were defined, namely county or city, region (Northern, Central, Southern, and Eastern Taiwan, and local administrative area (special municipality, provincial city, county-administered city, township, and aboriginal area.Of the regions, Northern Taiwan had the highest incidence rate at 139.6 per million person-years, followed by Central (132.8, Southern (131.8, and Eastern (128.4 Taiwan. Significantly higher standardized rate ratios (SRRs were observed in Northern Taiwan (SRR = 1.06, 95% confidence interval [CI] = 1.02-1.10 and at the township level (SRR = 1.07, 95% CI = 1.03-1.11. Of the cities or counties, New Taipei City yielded the highest SRR (1.08, followed by Taipei City (SRR = 1.07. A comparison of the rates in the four regions and the remainder of Taiwan according to cancer type revealed that only the rate of neuroblastomas in Eastern Taiwan was significantly low. Trend analysis showed that the most significant increase in incidence rate was observed at the township level, with an annual percent change of 1.8% during the 15-year study period.The high rate of childhood cancer in Northern Taiwan and at the township level deserves further attention. The potential impacts of environmental factors on the upward trend of childhood cancer incidence rate in townships warrant further investigation.

  10. Symposium on Geographic Information Systems.

    Science.gov (United States)

    Felleman, John, Ed.

    1990-01-01

    Six papers on geographic information systems cover the future of geographic information systems, land information systems modernization in Wisconsin, the Topologically Integrated Geographic Encoding and Referencing (TIGER) System of the U.S. Bureau of the Census, satellite remote sensing, geographic information systems and sustainable development,…

  11. The structural equation analysis of childhood abuse, adult stressful life events, and temperaments in major depressive disorders and their influence on refractoriness

    Directory of Open Access Journals (Sweden)

    Toda H

    2015-08-01

    Full Text Available Hiroyuki Toda,1 Takeshi Inoue,2,3 Tomoya Tsunoda,1 Yukiei Nakai,2 Masaaki Tanichi,1 Teppei Tanaka,1 Naoki Hashimoto,2 Yasuya Nakato,2 Shin Nakagawa,2 Yuji Kitaichi,2 Nobuyuki Mitsui,2 Shuken Boku,4 Hajime Tanabe,5 Masashi Nibuya,1 Aihide Yoshino,1 Ichiro Kusumi2 1Department of Psychiatry, National Defense Medical College, Tokorozawa, Saitama, Japan; 2Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan; 3Department of Psychiatry, Tokyo Medical University, Tokyo, Japan; 4Department of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Japan; 5Department of Clinical Human Sciences, Graduate School of Humanities and Social Sciences, Shizuoka University, Shizuoka, Japan Background: Previous studies have shown the interaction between heredity and childhood stress or life events on the pathogenesis of a major depressive disorder (MDD. In this study, we tested our hypothesis that childhood abuse, affective temperaments, and adult stressful life events interact and influence the diagnosis of MDD. Patients and methods: A total of 170 healthy controls and 98 MDD patients were studied using the following self-administered questionnaire surveys: the Patient Health Questionnaire-9 (PHQ-9, the Life Experiences Survey, the Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego Autoquestionnaire, and the Child Abuse and Trauma Scale (CATS. The data were analyzed with univariate analysis, multivariable analysis, and structural equation modeling. Results: The neglect scores of the CATS indirectly predicted the diagnosis of MDD through cyclothymic and anxious temperament scores of the Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego Autoquestionnaire in the structural equation modeling. Two temperaments – cyclothymic and anxious – directly predicted the diagnosis of MDD. The validity of this result was supported by the results of the stepwise multivariate logistic regression analysis

  12. A geographical information system-based analysis of cancer mortality and population exposure to coal mining activities in West Virginia, United States of America.

    Science.gov (United States)

    Hendryx, Michael; Fedorko, Evan; Anesetti-Rothermel, Andrew

    2010-05-01

    Cancer incidence and mortality rates are high in West Virginia compared to the rest of the United States of America. Previous research has suggested that exposure to activities of the coal mining industry may contribute to elevated cancer mortality, although exposure measures have been limited. This study tests alternative specifications of exposure to mining activity to determine whether a measure based on location of mines, processing plants, coal slurry impoundments and underground slurry injection sites relative to population levels is superior to a previously-reported measure of exposure based on tons mined at the county level, in the prediction of age-adjusted cancer mortality rates. To this end, we utilize two geographical information system (GIS) techniques--exploratory spatial data analysis and inverse distance mapping--to construct new statistical analyses. Total, respiratory and "other" age-adjusted cancer mortality rates in West Virginia were found to be more highly associated with the GIS-exposure measure than the tonnage measure, before and after statistical control for smoking rates. The superior performance of the GIS measure, based on where people in the state live relative to mining activity, suggests that activities of the industry contribute to cancer mortality. Further confirmation of observed phenomena is necessary with person-level studies, but the results add to the body of evidence that coal mining poses environmental risks to population health in West Virginia.

  13. A geographical information system-based analysis of cancer mortality and population exposure to coal mining activities in West Virginia, United States of America

    Directory of Open Access Journals (Sweden)

    Michael Hendryx

    2010-05-01

    Full Text Available Cancer incidence and mortality rates are high in West Virginia compared to the rest of the United States of America. Previous research has suggested that exposure to activities of the coal mining industry may contribute to elevated cancer mortality, although exposure measures have been limited. This study tests alternative specifications of exposure to mining activity to determine whether a measure based on location of mines, processing plants, coal slurry impoundments and underground slurry injection sites relative to population levels is superior to a previously-reported measure of exposure based on tons mined at the county level, in the prediction of age-adjusted cancer mortality rates. To this end, we utilize two geographical information system (GIS techniques – exploratory spatial data analysis and inverse distance mapping – to construct new statistical analyses. Total, respiratory and “other” age-adjusted cancer mortality rates in West Virginia were found to be more highly associated with the GIS-exposure measure than the tonnage measure, before and after statistical control for smoking rates. The superior performance of the GIS measure, based on where people in the state live relative to mining activity, suggests that activities of the industry contribute to cancer mortality. Further confirmation of observed phenomena is necessary with person-level studies, but the results add to the body of evidence that coal mining poses environmental risks to population health in West Virginia.

  14. Making Geographical Futures

    Science.gov (United States)

    Morgan, John

    2015-01-01

    Although there are surprisingly few academic books about geography with the term "future" or "futures" in their titles, this paper indicates that for much of the twentieth century geographers contributed to important discussions about the shape of worlds to come. The paper offers a review of these debates within Anglo-American…

  15. Impact of vaccine herd-protection effects in cost-effectiveness analyses of childhood vaccinations. A quantitative comparative analysis

    Science.gov (United States)

    Maldonado, Yvonne; Ioannidis, John P. A.; Contopoulos-Ioannidis, Despina

    2017-01-01

    Background Inclusion of vaccine herd-protection effects in cost-effectiveness analyses (CEAs) can impact the CEAs-conclusions. However, empirical epidemiologic data on the size of herd-protection effects from original studies are limited. Methods We performed a quantitative comparative analysis of the impact of herd-protection effects in CEAs for four childhood vaccinations (pneumococcal, meningococcal, rotavirus and influenza). We considered CEAs reporting incremental-cost-effectiveness-ratios (ICERs) (per quality-adjusted-life-years [QALY] gained; per life-years [LY] gained or per disability-adjusted-life-years [DALY] avoided), both with and without herd protection, while keeping all other model parameters stable. We calculated the size of the ICER-differences without vs with-herd-protection and estimated how often inclusion of herd-protection led to crossing of the cost-effectiveness threshold (of an assumed societal-willingness-to-pay) of $50,000 for more-developed countries or X3GDP/capita (WHO-threshold) for less-developed countries. Results We identified 35 CEA studies (20 pneumococcal, 4 meningococcal, 8 rotavirus and 3 influenza vaccines) with 99 ICER-analyses (55 per-QALY, 27 per-LY and 17 per-DALY). The median ICER-absolute differences per QALY, LY and DALY (without minus with herd-protection) were $15,620 (IQR: $877 to $48,376); $54,871 (IQR: $787 to $115,026) and $49 (IQR: $15 to $1,636) respectively. When the target-vaccination strategy was not cost-saving without herd-protection, inclusion of herd-protection always resulted in more favorable results. In CEAs that had ICERs above the cost-effectiveness threshold without herd-protection, inclusion of herd-protection led to crossing of that threshold in 45% of the cases. This impacted only CEAs for more developed countries, as all but one CEAs for less developed countries had ICERs below the WHO-cost-effectiveness threshold even without herd-protection. In several analyses, recommendation for the

  16. Short sleep duration and childhood obesity: cross-sectional analysis in Peru and patterns in four developing countries.

    Directory of Open Access Journals (Sweden)

    Rodrigo M Carrillo-Larco

    Full Text Available BACKGROUND: We aimed to describe the patterns of nutritional status and sleep duration in children from Ethiopia, India, Peru and Vietnam; to assess the association between short sleep duration and overweight and obesity, and if this was similar among boys and girls in Peru. METHODS AND FINDINGS: Analysis of the Young Lives Study, younger cohort, third round. In Ethiopia there were 1,999 observations, 2,011, 2,052 and 2,000 in India, Peru and Vietnam, respectively. Analyses included participants with complete data for sleep duration, BMI, sex and age; missing data: 5.9% (Ethiopia, 4.1% (India, 6.0% (Peru and 4.5% (Vietnam. Exposure was sleep duration per day: short (<10 hours versus regular (10-11 hours. Outcome was overweight and obesity. Multivariable analyses were conducted using a hierarchical approach to assess the effect of variables at different levels. Overweight/obesity prevalence was 0.5%/0.2% (Ethiopia, 1.3%/0.3% (India, 6.1%/2.8% (Vietnam, and 15.8%/5.4% (Peru. Only Peruvian data was considered to explore the association between short sleep duration and overweight and obesity, with 1,929 children, aged 7.9±0.3 years, 50.3% boys. Short and regular sleep duration was 41.6% and 55.6%, respectively. Multivariable models showed that obesity was 64% more prevalent among children with short sleep duration, an estimate that lost significance after controlling for individual- and family-related variables (PR: 1.15; 95%CI: 0.81-1.64. Gender was an effect modifier of the association between short sleep duration and overweight (p = 0.030 but not obesity (p = 0.533: the prevalence ratio was greater than one across all the models for boys, yet it was less than one for girls. CONCLUSIONS: Childhood overweight and obesity have different profiles across developing settings. In a sample of children living in resource-limited settings in Peru there is no association between short sleep duration and obesity; the crude association was slightly

  17. Life course pathways of adverse childhood experiences toward adult psychological well-being: A stress process analysis.

    Science.gov (United States)

    Nurius, Paula S; Green, Sara; Logan-Greene, Patricia; Borja, Sharon

    2015-07-01

    Growing evidence suggests that toxic stressors early in life not only convey developmental impacts but also augment risk of proliferating chains of additional stressors that can overwhelm individual coping and undermine recovery and health. Examining trauma within a life course stress process perspective, we posit that early childhood adversity carries a unique capacity to impair adult psychological well-being both independent of and cumulative with other contributors, including social disadvantage and stressful adult experiences. This study uses data from a representative population-based health survey (N=13,593) to provide one of the first multivariate assessments of unique, cumulative, and moderated effects of adverse childhood experiences (ACEs) toward explaining 3 related yet distinct measures of adult mental health: perceived well-being, psychological distress, and impaired daily activities. Results demonstrate support for each set of hypothesized associations, including exacerbation and amelioration of ACEs effects by adult stress and resilience resources, respectively. Implications for services and future research are discussed.

  18. Individual and family eating patterns during childhood and early adolescence: an analysis of associated eating disorder factors.

    Science.gov (United States)

    Fernández-Aranda, Fernando; Krug, Isabel; Granero, Roser; Ramón, Jose M; Badia, Anna; Giménez, Laura; Solano, Raquel; Collier, David; Karwautz, Andreas; Treasure, Janet

    2007-09-01

    To examine whether there is an association between individual and family eating patterns during childhood and the likelihood of developing an eating disorder (ED) later in life. The sample comprised 261 eating disorder patients [33.5% [N=88] anorexia nervosa (AN), 47.2% [N=123] with bulimia nervosa (BN) and 19.3% [N=50] with Eating Disorders Not Otherwise Specified (EDNOS)] and 160 healthy controls from the Province of Catalonia, Spain, who were matched for age and education. All patients were consecutively admitted to our Psychiatry Department and were diagnosed according to DSM-IV criteria. Participants completed the Early Eating Environmental Subscale of the Cross-Cultural (Environmental) Questionnaire (CCQ), a retrospective measure of childhood eating attitudes and behaviours. In the control group, also the General Health Questionnaire-28 (GHQ-28) was used. During childhood and early adolescence, the following main factors were identified to be linked to eating disorders: eating excessive sweets and snacks and consuming food specially prepared for the respondent. Conversely, regular breakfast consumption was negatively associated with an eating disorder. Compared to healthy controls, eating disorder patients report unfavourable eating patterns early in life, which in conjunction with an excessive importance given to food by the individual and the family may increase the likelihood for developing a subsequent eating disorder.

  19. An evidence-update on the prospective relationship between childhood sedentary behaviour and biomedical health indicators: a systematic review and meta-analysis.

    Science.gov (United States)

    van Ekris, E; Altenburg, T M; Singh, A S; Proper, K I; Heymans, M W; Chinapaw, M J M

    2016-09-01

    Evidence for adverse health effects of excessive sedentary behaviour in children is predominantly based on cross-sectional studies, measuring TV viewing as proxy for sedentary behaviour. This systematic review and meta-analysis summarizes the evidence on the prospective relationship between childhood sedentary behaviour and biomedical health indicators, overall and stratified by type of sedentary behaviour (TV viewing, computer use/games, screen time and objective sedentary time). PubMed, EMBASE, PsycINFO and Cochrane were systematically searched till January 2015. Methodological quality of all included studies was scored, and a best evidence synthesis was applied. We included 109 studies of which 19 were of high quality. We found moderate-to-strong evidence for a relationship of overall sedentary time with some anthropometrics (overweight/obesity, weight-for-height), one cardiometabolic biomarker (HDL-cholesterol) and some fitness indicators (fitness, being unfit). For other health indicators, we found no convincing evidence because of inconsistent or non-significant findings. The evidence varied by type of sedentary behaviour. The meta-analysis indicated that each additional baseline hour of TV viewing (β = 0.01, 95%CI = [-0.002; 0.02]) or computer use (β = 0.00, 95%CI = [-0.004; 0.01]) per day was not significantly related with BMI at follow-up. We conclude that the evidence for a prospective relationship between childhood sedentary behaviour and biomedical health is in general unconvincing.

  20. Familial aggregation and childhood blood pressure.

    Science.gov (United States)

    Wang, Xiaoling; Xu, Xiaojing; Su, Shaoyong; Snieder, Harold

    2015-01-01

    There is growing concern about elevated blood pressure (BP) in children. The evidence for familial aggregation of childhood BP is substantial. Twin studies have shown that a large part of the familial aggregation of childhood BP is due to genes. The first part of this review provides the latest progress in gene finding for childhood BP, focusing on the combined effects of multiple loci identified from the genome-wide association studies on adult BP. We further review the evidence on the contribution of the genetic components of other family risk factors to the familial aggregation of childhood BP including obesity, birth weight, sleep quality, sodium intake, parental smoking, and socioeconomic status. At the end, we emphasize the promise of using genomic-relatedness-matrix restricted maximum likelihood (GREML) analysis, a method that uses genome-wide data from unrelated individuals, in answering a number of unsolved questions in the familial aggregation of childhood BP.

  1. Childhood Brain Tumors

    Science.gov (United States)

    Brain tumors are abnormal growths inside the skull. They are among the most common types of childhood ... still be serious. Malignant tumors are cancerous. Childhood brain and spinal cord tumors can cause headaches and ...

  2. Can Stable Isotope combined with Trace Element Analysis distinguish between pure and g.g.A. (protected geographical indication, P.G.I.) certified Pumpkin Seed Oils?

    Science.gov (United States)

    Meier-Augenstein, Wolfram; Kemp, Helen; Midwood, Andy

    2013-04-01

    Styrian Pumpkin Seed Oil is a premium single seed vegetable oil that is uniquely linked to the geographic region of Styria where it is grown and produced. In 1996, the strong regional ties of this typical Styrian speciality were recognised by the EU-Commission who declared "Styrian Pumpkin Seed Oil P.G.I." as a Protected Geographical Indication (article 5 VO(EWG) Nr. 2081/92). In 1998, more than 2,000 domestic pumpkin seed producers and 30 oil mills formed an association of Styrian pumpkin seed oil producers, which is now called the "Gemeinschaft Steirisches Kürbiskernöl g.g.A.". This producers' association was formed in order to protect the regionality and the high quality of Styrian Pumpkin Seed Oil P.G.I. Procedures implemented by this producers' association document every step in the process from pumpkin seeds to seed crushing in oil mills and finally bottling of Styrian Pumpkin Seed Oil P.G.I., keeping a contiguous record of all production steps including annual harvest amounts. This permits full traceability of every bottle of Styrian Pumpkin Seed Oil P.G.I from harvest to the finished, bottled products found on the shelf of delis and even supermarkets. Despite these efforts of the producers' association, there have been repeated claims of g.g.A. (P.G.I.) certified bottles of Styrian Pumpkin Seed Oil (PSO) having been analysed independently and shown to contain either mixtures of Styrian and non-Styrian PSO or no Styrian PSO at all. Since keeping records of annual harvest amounts of pumpkin seeds would make it very difficult for an "over-production" by mixing or substitution of alien PSO's to go unnoticed, we formed the hypothesis that the red-flagged bottles could have been counterfeits containing alien PSO with bottles sporting fake g.g.A. seals and fake serial numbers. An alternative hypothesis was that the chosen method of detection of allegedly misrepresented g.g.A. Styrian PSO resulted in a high number of false negatives thus incorrectly rejecting

  3. Analysis on the Ancient Geographical Environment for Jiangjiashan Vestige in Neolithic Age%蒋家山新石器遗址古地理环境分析

    Institute of Scientific and Technical Information of China (English)

    周秉根; 王心源; 陆应诚; 李中轩; 张圆刚

    2011-01-01

    蒋家山文化遗址出土文物400多件,主要有石镞、网坠、石锛和石刀等,石器中含石玉.C14测定年龄最早为5070±150a.B.属新石器晚期遗址.根据钻孔资料分析和现场勘察,将家山文化遗址有居民生活区,部族首领生活和指挥区,燎望台等功能区,初步研究,该文化遗址为新石器晚期生活在太平盆地中的一个部落,其文明发展有3个活动期,期间有四个文化间断期,其文化变化的原因与古气候等古地理环境有关.%Over 400 pieces of unearthed relics were excavated at vestige of Jiangjiashan. They mainly consist of stone arrow-heads, net pendants, stone adzes and stone knives etc. Some of those stone implements are stone jade. Via radiocarbon dating (C14) determines the age of the Jiangjiashan vestige being the late new stone Age. On the ground of analysis of drilling materials and on-the-spot investigations, the cultural vestige of Jiang Jiashan may be divided into residential areas, living area for tribal leaders, command post and lookout tower areas etc. Preliminary research indicated the cultural vestige is traces of a tribe living on the Taiping platform in the late Neolithic Age. Its civilization process included three active periods, simultaneously, in the course of it there were four cultural intermissions. Correspondingly, the cultural change characteristics are closely related to local ancient geographical environment.

  4. Análisis geográfico de las actuales relaciones comerciales entre Canarias y Marruecos / Geographic analysis of commercial relations between the Canary Islands and Morocco

    Directory of Open Access Journals (Sweden)

    Ramón Díaz Hernández

    2014-12-01

    Full Text Available En este trabajo formulamos como hipótesis de partida que Canarias, como frontera meridional de Europa, en un contexto de creciente internacionalización, tiene en los mercados africanos una gran baza histórica que desempeñar. Dado el interés general que este asunto suscita entre las ciencias sociales, se requiere abordarlo desde el análisis geográfico. Para cumplimentar este estudio se emplearon las estadísticas que ofrecen organismos oficiales como el Instituto Nacional de Estadística, Instituto Canario de Estadística, Agencia Estatal de la Administración Tributaria, Instituto de Comercio Exterior y entidades internacionales como la Conferencia de las Naciones Unidas para el Comercio y el Desarrollo (UNCTAD y la Organización Mundial del Comercio (OCM.In this work we formulate the hypothesis that the Canary Islands, as Europe’s southern border, must develop an important role in African markets, in a context of increasing internationalization. Because of the general interest in this issue within the social sciences, to address it from the geographic analysis is required. This study is based, on the one hand, on statistics provided by Spanish government agencies such as the National Statistics Institute, the Canary Institute of Statistics, the State Tax Administration Agency and the Institute of Foreign Trade and, on the other hand, by international entities such as the United Nations Conference for Trade and Development (UNCTAD and the World Trade Organization (WTO.

  5. Geographical Analysis for Detecting High-Risk Areas for Bovine/Human Rabies Transmitted by the Common Hematophagous Bat in the Amazon Region, Brazil

    Science.gov (United States)

    Begot, Alberto L.; Ramos, Ofir de S.

    2016-01-01

    Background The common hematophagous bat, Desmodus rotundus, is one of the main wild reservoirs of rabies virus in several regions in Latin America. New production practices and changed land use have provided environmental features that have been very favorable for D. rotundus bat populations, making this species the main transmitter of rabies in the cycle that involves humans and herbivores. In the Amazon region, these features include a mosaic of environmental, social, and economic components, which together creates areas with different levels of risk for human and bovine infections, as presented in this work in the eastern Brazilian Amazon. Methodology We geo-referenced a total of 175 cases of rabies, of which 88% occurred in bovines and 12% in humans, respectively, and related these cases to a number of different geographical and biological variables. The spatial distribution was analyzed using the Kernel function, while the association with independent variables was assessed using a multi-criterion Analytical Hierarchy Process (AHP) technique. Findings The spatiotemporal analysis of the occurrence of rabies in bovines and humans found reduction in the number of cases in the eastern state of Pará, where no more cases were recorded in humans, whereas high infection rates were recorded in bovines in the northeastern part of the state, and low rates in the southeast. The areas of highest risk for bovine rabies are found in the proximity of rivers and highways. In the case of human rabies, the highest concentration of high-risk areas was found where the highway network coincides with high densities of rural and indigenous populations. Conclusion The high-risk areas for human and bovine rabies are patchily distributed, and related to extensive deforested areas, large herds of cattle, and the presence of highways. These findings provide an important database for the generation of epidemiological models that could support the development of effective prevention

  6. Analysis of matched geographical areas to study potential links between environmental exposure to oil refineries and non-Hodgkin lymphoma mortality in Spain

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    Ramis Rebeca

    2012-02-01

    Full Text Available Abstract Background Emissions from refineries include a wide range of substances, such as chrome, lead, nickel, zinc, arsenic, cadmium, benzene, dioxins and furans, all of which are recognized by the International Agency for Research on Cancer (IARC as carcinogens. Various studies have shown an association between non-Hodgkin lymphoma (NHL and residence in the vicinity of industrial areas; however, evidence of specific association between refineries and residence in the vicinity has been suggested but not yet established. The aim of this study is to investigate potential links between environmental exposure to emissions from refineries and non-Hodgkin lymphoma mortality in Spain. The spatial distribution of NHL in Spain has an unusual pattern with regions some showing higher risk than others. Methods We designed an analysis of matched geographical areas to examine non-Hodgkin lymphoma mortality in the vicinity of the 10 refineries sited in Spain over the period 1997-2006. Population exposure to refineries was estimated on the basis of distance from town of residence to the facility in a 10 km buffer. We defined 10 km radius areas to perform the matching, accounting for population density, level of industrialization and socio-demographic factors of the area using principal components analysis. For the matched towns we evaluated the risk of NHL mortality associated with residence in the vicinity of the refineries and with different regions using mixed Poisson models. Then we study the residuals to assess a possible risk trend with distance. Results Relative risks (RRs associated with exposure showed similar values for women and for men, 1.09 (0.97-1.24 and 1.12 (0.99-1.27. RRs for two regions were statistically significant: Canary Islands showed an excess of risk of 1.35 (1.05-1.72 for women and 1.50 (1.18-1.92 for men, whilst Galicia showed an excess of risk of 1.35 (1.04-1.75 for men, but not significant excess for women. Conclusions The results

  7. Remote sensing research in geographic education: An alternative view

    Science.gov (United States)

    Wilson, H.; Cary, T. K.; Goward, S. N.

    1981-01-01

    It is noted that within many geography departments remote sensing is viewed as a mere technique a student should learn in order to carry out true geographic research. This view inhibits both students and faculty from investigation of remotely sensed data as a new source of geographic knowledge that may alter our understanding of the Earth. The tendency is for geographers to accept these new data and analysis techniques from engineers and mathematicians without questioning the accompanying premises. This black-box approach hinders geographic applications of the new remotely sensed data and limits the geographer's contribution to further development of remote sensing observation systems. It is suggested that geographers contribute to the development of remote sensing through pursuit of basic research. This research can be encouraged, particularly among students, by demonstrating the links between geographic theory and remotely sensed observations, encouraging a healthy skepticism concerning the current understanding of these data.

  8. Differences in Childhood Leukemia Incidence and Survival between Southern Thailand and the United States: A Population-Based Analysis

    Science.gov (United States)

    Demanelis, Kathryn; Sriplung, Hutcha; Meza, Rafael; Wiangnon, Surapon; Rozek, Laura S.; Scheurer, Michael E.; Lupo, Philip J.

    2015-01-01

    BACKGROUND Childhood leukemia incidence and survival varies globally, and this variation may be attributed to environmental risk factors, genetics, and/or disparities in diagnosis and treatment. PROCEDURE We analyzed childhood leukemia incidence and survival trends in children age 0–19 years from 1990 to 2011 in Songkhla, Thailand (n=316) and compared these results to US data from the Surveillance, Epidemiology, and End Results (SEER) registry (n=6,738). We computed relative survival using Ederer II and estimated survival functions using the Kaplan-Meier method. Changes in incidence and five-year survival by year of diagnosis were evaluated using joinpoint regression and are reported as annual percent changes (APC). RESULTS The age-standardized incidence of leukemia was 3.2 and 4.1 cases per 100,000 in Songkhla and SEER-9, respectively. In Songkhla, incidence from 1990–2011 significantly increased for leukemia (APC=1.7%, p=0.031) and acute lymphoblastic leukemia (ALL) (APC=1.8%, p=0.033). Acute myeloid leukemia (AML) incidence significantly increased (APC=4.2%, p=0.044) and was significantly different from the US (p=0.026), where incidence was stable during the same period (APC=0.3%, p=0.541). The overall five-year relative survival for leukemia was lower than that reported in the US (43% vs. 79%). Five-year survival significantly improved by at least 2% per year from 1990–2011 in Songkhla for leukemia, ALL, and AML (p<0.050). CONCLUSIONS While leukemia and ALL incidence increased in Songkhla, differences in leukemia trends, particularly AML incidence, may suggest etiologic or diagnostic differences between Songkhla and the US. This work highlights the importance of evaluating childhood cancer trends in low- and middle-income countries. PMID:25962869

  9. CHILDHOOD AS A POSSIBILITY FOR LYRISM WITHIN WAR ANESTHETICS: AN ANALYSIS OF “BOM DIA, CAMARADAS” (GOOD MORNING, COMRADES

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    Bruno Cardoso

    2014-11-01

    Full Text Available This abstract analyzes the Angolan novel Bom dia camaradas from the Af­rican writer Ondjacki, in a manner which we problematize the significance of the memoir and the childhood at the building of the narrative descrip­tion. Let us verify bythe literary work, a double reflection novel, once the Angolan post-independence reality presents itself as being transfigured by the child as the main narrator, such as the other supporting voices around the entire narrative, bringing to the protagonist the news from the civil war in this African country.

  10. Geographical Income Polarization

    DEFF Research Database (Denmark)

    Azhar, Hussain; Jonassen, Anders Bruun

    In this paper we estimate the degree, composition and development of geographical income polarization based on data at the individual and municipal level in Denmark from 1984 to 2002. Rising income polarization is reconfirmed when applying new polarization measures, the driving force being greater...... inter municipal income inequality. Counter factual simulations show that rising property prices to a large part explain the rise in polarization. One side-effect of polarization is tendencies towards a parallel polarization of residence location patterns, where low skilled individuals tend to live...

  11. Spatial Analysis in Educational Administration: Exploring the Role of G.I.S. (Geographical Information Systems) as an Evaluative Tool in the Public School Board Setting.

    Science.gov (United States)

    Brown, Robert S.; Baird, William; Rosolen, Lisa

    In January 1998, seven school boards amalgamated to form the Toronto District School Board, a board responsible for 600 schools. To deal with the complexities of the new entity, researchers have been using geographical information systems (GIS). GIS are computer-based tools for mapping. They store information as a collection of thematic layers or…

  12. Gender and Geographic Differences in the Prevalence of Autism Spectrum Disorders in Children: Analysis of Data from the National Disability Registry of Taiwan

    Science.gov (United States)

    Lai, Der-Chung; Tseng, Yen-Cheng; Hou, Yuh-Ming; Guo, How-Ran

    2012-01-01

    The prevalence of autism spectrum disorders (ASD) in the world has increased dramatically in the recent decades. However, data at the national level are limited, and geographic differences are seldom evaluated. According to the law, the local governments in Taiwan began to certify disabled residents and provide various services in 1980, and the…

  13. An Analysis of the Geographic Distribution of Recently Graduated Dentists from the University of Western Australia: The World's Most Isolated Dental School

    Science.gov (United States)

    Gurbuxani, Amit; Kruger, Estie; Tennant, Marc

    2013-01-01

    Objective: The purpose of this study was to determine the geographic distribution of all new dentists who graduated over a period of six years. Perth, the capital city of Western Australia, is one of the world's most isolated cities, with a population of approximately 1.6 million people, situated over 2000km from its nearest next major…

  14. Management of childhood stuttering.

    Science.gov (United States)

    Onslow, Mark; O'Brian, Sue

    2013-02-01

    Stuttering is a speech disorder that begins during the first years of life and is among the most prevalent of developmental disorders. It appears to be a problem with neural processing of speech involving genetics. Onset typically occurs during the first years of life, shortly after language development begins. Clinical presentation during childhood is interrupted and effortful speech production, often with rapid onset. If not corrected during early childhood, it becomes intractable and can cause psychological, social, educational and occupational problems. There is evidence from replicated clinical trials to support early intervention during the pre-school years. Meta-analysis of studies indicates that children who receive early intervention during the pre-school years are 7.7 times more likely to have resolution of their stuttering. Early intervention is recommended with a speech pathologist. Some children who begin to stutter will recover without such intervention. However, the number of such recoveries is currently not known, and it is not possible to predict which children are likely to recover naturally. Consequently, the current best practice is for speech pathologists to monitor children for signs of natural recovery for up to 1 year before beginning treatment.

  15. Targeted Behavioral Therapy for childhood generalized anxiety disorder: a time-series analysis of changes in anxiety and sleep.

    Science.gov (United States)

    Clementi, Michelle A; Alfano, Candice A

    2014-03-01

    This study examined the efficacy of Targeted Behavioral Therapy (TBT), a newly developed intervention targeting features of childhood generalized anxiety disorder (GAD). Using a time-series design, 4 children (7-12 years) with primary GAD were treated with TBT, which includes sleep improvement strategies, systematic desensitization for reducing intolerance of uncertainty, and in vivo exposures for anxiety. Diagnostic interviews and questionnaires were administered at baseline, post-treatment and 3 months follow-up. Anxiety symptoms and sleep characteristics/problems were rated weekly during a 4-week baseline and 14-weeks of treatment. Two children remitted at post-treatment and no child had a GAD diagnosis at follow-up. Child but not parent report revealed improvements in both worry and sleep. Despite improvements from pre- to post-assessment, considerable symptom fluctuation observed during the baseline period preclude conclusion that symptom changes are specifically attributable to the course of treatment. Overall, preliminary support is provided for the efficacy of TBT for childhood GAD.

  16. Elevated specific peripheral cytokines found in major depressive disorder patients with childhood trauma exposure: a cytokine antibody array analysis.

    Science.gov (United States)

    Lu, Shaojia; Peng, Hongjun; Wang, Lifeng; Vasish, Seewoobudul; Zhang, Yan; Gao, Weijia; Wu, Weiwei; Liao, Mei; Wang, Mi; Tang, Hao; Li, Wenping; Li, Weihui; Li, Zexuan; Zhou, Jiansong; Zhang, Zhijun; Li, Lingjiang

    2013-10-01

    Taking into consideration the previous evidence of revealing the relationship of early life adversity, major depressive disorder (MDD), and stress-linked immunological changes, we recruited 22 MDD patients with childhood trauma exposures (CTE), 21 MDD patients without CTE, and 22 healthy controls without CTE, and then utilized a novel cytokine antibody array methodology to detect potential biomarkers underlying MDD in 120 peripheral cytokines and to evaluate the effect of CTE on cytokine changes in MDD patients. Although 13 cytokines were identified with highly significant differences in expressions between MDD patients and normal controls, this relationship was significantly attenuated and no longer significant after consideration of the effect of CTE in MDD patients. Depressed individuals with CTE (TD patients) were more likely to have higher peripheral levels of those cytokines. Severity of depression was associated with plasma levels of certain increased cytokines; meanwhile, the increased cytokines led to a proper separation of TD patients from normal controls during clustering analyses. Our research outcomes add great strength to the relationship between depression and cytokine changes and suggest that childhood trauma may play a vital role in the co-appearance of cytokine changes and depression.

  17. Effects of multiple maternal relationship transitions on offspring antisocial behavior in childhood and adolescence: a cousin-comparison analysis.

    Science.gov (United States)

    Goodnight, Jackson A; D'Onofrio, Brian M; Cherlin, Andrew J; Emery, Robert E; Van Hulle, Carol A; Lahey, Benjamin B

    2013-02-01

    Previous studies of the association between multiple parental relationship transitions (i.e., when a parent begins or terminates an intimate relationship involving cohabitation) and offspring antisocial behavior have varied in their efforts to rule out confounding influences, such as parental antisocial behavior and low income. They also have been limited in the representativeness of their samples. Thus, it remains unclear to what degree parents' multiple relationship transitions have independent effects on children's antisocial behavior. Analyses were conducted using data on 8,652 6-9-year-old, 6,911 10-13-year-old, and 6,495 14-17-year-old offspring of a nationally representative sample of U.S. women. Cousin-comparisons were used in combination with statistical covariates to evaluate the associations between maternal relationship transitions and offspring antisocial behavior in childhood and adolescence. Cousin-comparisons suggested that associations between maternal relationship transitions and antisocial behavior in childhood and early adolescence are largely explained by confounding factors. In contrast, the associations between maternal relationship transitions and offspring delinquency in late adolescence were robust to measured and unmeasured confounds. The present findings suggest that interventions aimed at reducing exposure to parental relationship transitions or addressing the psychosocial consequences of exposure to parental relationship transitions could reduce risk for offspring delinquency in late adolescence.

  18. Optimization analysis of bus lines based on geographical information system%基于GIS的公交线路优化分析

    Institute of Scientific and Technical Information of China (English)

    焦明连; 贾艳红; 陈海燕

    2013-01-01

    针对公交线路规划设计的特点与目标,以实地采集数据及地图数据为基础,利用GIS空间分析中的缓冲区分析、叠置分析及网络分析功能,以江苏省连云港市新浦区某实验区为例,对研究区域的公交站点辐射范围、区域交通设施完备度、区域交通便捷度和区域交通道路通达性指标进行了分析。并结合空间信息叠置原理,以沟通淮海工学院苍梧校区与通灌校区的公交线路为例,以路线长短和乘客数量为权重进行网络分析,并结合研究区公交站点辐射范围、区域交通设施完备度、区域交通便捷度和区域交通道路通达性分析结果,对现有公交线路优化问题进行了分析。明确了目前公共交通存在的若干问题,为进一步实施公交线网优化方案及提高公交运行效率提供参考。研究表明,GIS技术对于解决城市公共交通线路优化和分析问题具有重要作用。%According to the characteristics and objectives of planning and design of bus lines, some indices are analyzed based on the map and data acquiring on the spot in Xinpu District of Lianyungang City in Jiangsu Province, China.The indices include the radiation scope of bus stops, the facilities complete degree of regional transportation, the convenience degree of regional transportation and the accessible degree of regional road.The technology of the geographical information system ( GIS) is introduced to this study, including spatial buffer analysis and spatial information overlay and network analysis.The optimal choice for the bus line from Cangwu campus to Tongguan campus of the Hua-ihai Institute of Technology is carried out based on the spatial network analysis by the weight of the length of bus lines and the quantity of passengers.The results are imported into this optimal choice simultaneously from the radiation scope of bus stops, the facilities complete degree of regional trans-portation, the

  19. Dynamic analysis of eco-environmental changes based on remote sensing and geographic information system: an example in Longdong region of the Chinese Loess Plateau

    Science.gov (United States)

    Liu, L. C.; Dong, X. F.; Wang, J. H.

    2007-11-01

    The Chinese Loess Plateau is suffering from severe soil erosion. The eco-environmental changes of the plateau are believed to have an important influence on global eco-environmental sustainability; hence, this problem has attracted considerable attention from scientists around the world. This study has two purposes; application of remote sensing (RS) and geographic information system (GIS) techniques in the dynamic analysis of eco-environmental changes in the semiarid zone; and using the Longdong region of the Chinese Loess Plateau as an example, to make dynamic analysis of the eco-environmental changes of the region during the 1986 2004 period and identify controlling factors. Landsat Thematic Mapper (TM) data at a spatial resolution of 30 m were used for analysis. Two training areas were selected in Jingning and Qingcheng counties for analysis using 10-m resolution SPOT and Landsat TM data. The satellite RS images were obtained from the Institute of Remote Sensing Application (IRSA), Chinese Academy of Sciences (CAS). Each images was rectified by Albers Equal Area Conic projection based on 1:50,000 scale topographic maps after spectrum preparation of the images. To make the precision within 1 or 2 pixels, the accurate coordinative control points of the two systems were identified. Then the interpretation key was established based on the land use/cover survey in the study area. The images were classified into six primary environmental types (farmland, forest, grassland, water, construction area, and desert) and 25 sub-types using a visual image interactive interpretation method to obtain vector and attribute data. The resultant accuracy of the land use/cover classification reached 95%. Finally, the transformation areas and ratios of various eco-environmental types in the region were calculated to obtain the transition matrixes of eco-environmental types in the two training areas, Jingning and Qingcheng. This study demonstrates that satellite RS and GIS techniques

  20. Land use suitability analysis of the Upper Basin of the Kara Menderes River using analytical hierarchy process and geographical information systems

    Directory of Open Access Journals (Sweden)

    Cengiz Akbulak

    2010-08-01

    Full Text Available Sustainable development links to a rationalistic and effective use of resources. Presently, growth in human needs for a variety of reasons causes a great pressure on the existing resources, which has induced in misuse-based deterioration of lands as well as increase in poverty and several kinds of social problems. In this context, due to rapid growth of population in Turkey, the most appropriate use of lands according to their potentials is essential, because sustainability of environments can only be achieved on condition that natural and cultural potentials are appointed and the land use is enforced in compliance with ecological properties. In previous attempts of land suitability analyses, the subject “the most proper use of land” has been the focus of several authors.In this study, land suitability analysis of the upper basin of the Kara Menderes River was carried out, which drains the Biga Peninsula, west of the Marmara Region in Turkey, on the basis of geographical information systems and analytical hierarchy process, a technique used for multi-criteria decision making studies. After the determination of suitability in terms of the main three land use types, i.e. agriculture, meadow-pasture and forest, an optimal land use map was produced and results were compared to the present-day land use situation. Based on optimal land use results, an area of 15.2% is suggested for agricultural activities. The area proposed for meadow-pasture lands corresponds to only about 8.5%. Forest areas constitute, however, the foremost class with the suggested value of 75,1%. When data from optimal land use is compared with that in the present-day conditions, it is noticed that the proportion of agricultural areas excesses the suggested value of optimal land use, as opposed to the proportions of forest and meadow-pasture areas having smaller distributions. This implies that some agricultural areas, which are recommended to be evaluated as forest and meadow

  1. Land use suitability analysis of the Upper Basin of the Kara Menderes River using analytical hierarchy process and geographical information systems

    Directory of Open Access Journals (Sweden)

    Cengiz Akbulak

    2010-08-01

    Full Text Available Sustainable development links to a rationalistic and effective use of resources. Presently, growth in human needs for a variety of reasons causes a great pressure on the existing resources, which has induced in misuse-based deterioration of lands as well as increase in poverty and several kinds of social problems. In this context, due to rapid growth of population in Turkey, the most appropriate use of lands according to their potentials is essential, because sustainability of environments can only be achieved on condition that natural and cultural potentials are appointed and the land use is enforced in compliance with ecological properties. In previous attempts of land suitability analyses, the subject “the most proper use of land” has been the focus of several authors.In this study, land suitability analysis of the upper basin of the Kara Menderes River was carried out, which drains the Biga Peninsula, west of the Marmara Region in Turkey, on the basis of geographical information systems and analytical hierarchy process, a technique used for multi-criteria decision making studies. After the determination of suitability in terms of the main three land use types, i.e. agriculture, meadow-pasture and forest, an optimal land use map was produced and results were compared to the present-day land use situation. Based on optimal land use results, an area of 15.2% is suggested for agricultural activities. The area proposed for meadow-pasture lands corresponds to only about 8.5%. Forest areas constitute, however, the foremost class with the suggested value of  75,1%. When data from optimal land use is compared with that in the present-day conditions, it is noticed that the proportion of agricultural areas excesses the suggested value of optimal land use, as opposed to the proportions of forest and meadow-pasture areas having smaller distributions. This implies that some agricultural areas, which are recommended to be evaluated as forest and

  2. Age-related macular degeneration with choroidal neovascularization in the setting of pre-existing geographic atrophy and ranibizumab treatment. Analysis of a case series and revision paper

    Directory of Open Access Journals (Sweden)

    Miguel Hage Amaro

    2012-12-01

    Full Text Available PURPOSE: To report the response of choroidal neovascularization (CNV to intravitreal ranibizumab treatment in the setting of age-related macular degeneration (AMD with extensive pre-existing geographic atrophy (GA and a revision paper. METHODS: This is a revision paper and a retrospective case series of 10 eyes in nine consecutive patients from a photographic database. The patients were actively treated with ranibizumab for neovascular AMD with extensive pre-existing GA. Patients were included if they had GA at or adjacent to the foveal center that was present before the development of CNV. The best corrected visual acuity and optical coherence tomography (OCT analysis of the central macular thickness were recorded for each visit. Serial injections of ranibizumab were administered until there was resolution of any subretinal fluid clinically or on OCT. Data over the entire follow-up period were analyzed for overall visual and OCT changes. All patients had been followed for at least 2 years since diagnosis. RESULTS: The patients received an average of 6 ± 3 intravitreal injections over the treatment period. Eight eyes had reduced retinal thickening on OCT. On average, the central macular thickness was reduced by 94 ± 101 µm. Eight eyes had improvement of one or more lines of vision, where as one eye had dramatic vision loss and one had no change. The average treatment outcome for all patients was -0.07 ± 4.25 logMAR units, which corresponded to a gain of 0.6 ± 4.4 lines of Snellen acuity. The treatment resulted in a good anatomic response with the disappearance of the subretinal fluid, improved visual acuity, and stabilized final visual results. CONCLUSION: The results of this case series suggest that the use of an intravitreal anti-vascular endothelial growth factor (VEGF agent (ranibizumab for CNV in AMD with extensive pre-existing GA is effective. Our results are not as striking as published results from large-scale trials of anti

  3. Clinical analysis of 396 cases of vitiligo in childhood%儿童白癜风396例临床分析

    Institute of Scientific and Technical Information of China (English)

    黄博; 许爱娥; 卢良君; 陈梅花; 常淑彪

    2008-01-01

    Objective To determine the clinical features of childhood vitiligo in Han nationality.Methods A standardized questionnaire was used to clinically investigate 396 cases of vitiligo in patients aged less than 12 years;825 adult patients with vitiligo served as controls.Data analysis was done by SPSS 10.0.Results In child patients with vitiligo,46.2% were males,and 53.8%females;there was no statistically significant difference in gender ratio between the childhood and adult groups(P<0.05).The incidence of segmental vitiligo was 33.3%in children,significantly higher than that in adult patients(13.5%).On the contrary,the incidence of generalized vitiligo was significantly lower in children han in adult patients(4.3%vs 11.6%).A family history of vitiligo was observed in 12.4%of children,and in 12.7% of adults,withoutsignificant difference between the two groups.For both childhood and adult vitiligo patients,the incidence of vitiligo was significantly higher in firSt-degree relatives than in second-degree relatives.The most common precipitating factor of childhood vitiligo was trauma.The incidence of halo nevi was higher in patients with childhood vitiligo compared to patients with adult vitiligo,while thyroid disease was seen more frequently in adult patients.Conclusion There are some differences in clinical characteristics of vitiligo between children and adults.%目的 探讨汉族儿童白癜风的临床特点.方法 采用问卷调查方式对浙江省396例儿童白癜风及825例成人白癜风患者进行临床分析,用SPSS 10.0软件包对资料进行分析.结果 396例儿童白癜风患者中男183例占46.2%,女213例占53.8%,与成年患者相比,男女之间无性别差异.儿童患者中节段型的比例为33.3%,明显高于成人患者的13.5%,泛发型比例为4.3%,显著低于成人患者的11.6%.儿童患者家族史阳性比例为12.4%,成人患者家族史阳性比例为12.7%,两组间差异无统计学意义.有家族史患者一级亲属的发

  4. ADAPTEITION STRATEGY OF GEOGRAPHICAL DISTRIBUTION OF DRAGONFLIES

    Directory of Open Access Journals (Sweden)

    Kh. A. Ketenchyev

    2011-01-01

    Full Text Available The article discusses some of the adaptive strategy of geographical distribution ofdragonflies. The basis of adaptive traits considered temperature. Together with the humidity is a major abiotic factor. Analysis of the phenomen will determine the strategy of distribution of dragonflies in the horizontal and vertical directions.

  5. Analyzing geographic clustered response

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.; Selvin, S.; Mohr, M.S.

    1991-08-01

    In the study of geographic disease clusters, an alternative to traditional methods based on rates is to analyze case locations on a transformed map in which population density is everywhere equal. Although the analyst's task is thereby simplified, the specification of the density equalizing map projection (DEMP) itself is not simple and continues to be the subject of considerable research. Here a new DEMP algorithm is described, which avoids some of the difficulties of earlier approaches. The new algorithm (a) avoids illegal overlapping of transformed polygons; (b) finds the unique solution that minimizes map distortion; (c) provides constant magnification over each map polygon; (d) defines a continuous transformation over the entire map domain; (e) defines an inverse transformation; (f) can accept optional constraints such as fixed boundaries; and (g) can use commercially supported minimization software. Work is continuing to improve computing efficiency and improve the algorithm. 21 refs., 15 figs., 2 tabs.

  6. Community structure analysis of transcriptional networks reveals distinct molecular pathways for early- and late-onset temporal lobe epilepsy with childhood febrile seizures.

    Science.gov (United States)

    Moreira-Filho, Carlos Alberto; Bando, Silvia Yumi; Bertonha, Fernanda Bernardi; Iamashita, Priscila; Silva, Filipi Nascimento; Costa, Luciano da Fontoura; Silva, Alexandre Valotta; Castro, Luiz Henrique Martins; Wen, Hung-Tzu

    2015-01-01

    Age at epilepsy onset has a broad impact on brain plasticity and epilepsy pathomechanisms. Prolonged febrile seizures in early childhood (FS) constitute an initial precipitating insult (IPI) commonly associated with mesial temporal lobe epilepsy (MTLE). FS-MTLE patients may have early disease onset, i.e. just after the IPI, in early childhood, or late-onset, ranging from mid-adolescence to early adult life. The mechanisms governing early (E) or late (L) disease onset are largely unknown. In order to unveil the molecular pathways underlying E and L subtypes of FS-MTLE we investigated global gene expression in hippocampal CA3 explants of FS-MTLE patients submitted to hippocampectomy. Gene coexpression networks (GCNs) were obtained for the E and L patient groups. A network-based approach for GCN analysis was employed allowing: i) the visualization and analysis of differentially expressed (DE) and complete (CO) - all valid GO annotated transcripts - GCNs for the E and L groups; ii) the study of interactions between all the system's constituents based on community detection and coarse-grained community structure methods. We found that the E-DE communities with strongest connection weights harbor highly connected genes mainly related to neural excitability and febrile seizures, whereas in L-DE communities these genes are not only involved in network excitability but also playing roles in other epilepsy-related processes. Inversely, in E-CO the strongly connected communities are related to compensatory pathways (seizure inhibition, neuronal survival and responses to stress conditions) while in L-CO these communities harbor several genes related to pro-epileptic effects, seizure-related mechanisms and vulnerability to epilepsy. These results fit the concept, based on fMRI and behavioral studies, that early onset epilepsies, although impacting more severely the hippocampus, are associated to compensatory mechanisms, while in late MTLE development the brain is less able to

  7. Community structure analysis of transcriptional networks reveals distinct molecular pathways for early- and late-onset temporal lobe epilepsy with childhood febrile seizures.

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Moreira-Filho

    Full Text Available Age at epilepsy onset has a broad impact on brain plasticity and epilepsy pathomechanisms. Prolonged febrile seizures in early childhood (FS constitute an initial precipitating insult (IPI commonly associated with mesial temporal lobe epilepsy (MTLE. FS-MTLE patients may have early disease onset, i.e. just after the IPI, in early childhood, or late-onset, ranging from mid-adolescence to early adult life. The mechanisms governing early (E or late (L disease onset are largely unknown. In order to unveil the molecular pathways underlying E and L subtypes of FS-MTLE we investigated global gene expression in hippocampal CA3 explants of FS-MTLE patients submitted to hippocampectomy. Gene coexpression networks (GCNs were obtained for the E and L patient groups. A network-based approach for GCN analysis was employed allowing: i the visualization and analysis of differentially expressed (DE and complete (CO - all valid GO annotated transcripts - GCNs for the E and L groups; ii the study of interactions between all the system's constituents based on community detection and coarse-grained community structure methods. We found that the E-DE communities with strongest connection weights harbor highly connected genes mainly related to neural excitability and febrile seizures, whereas in L-DE communities these genes are not only involved in network excitability but also playing roles in other epilepsy-related processes. Inversely, in E-CO the strongly connected communities are related to compensatory pathways (seizure inhibition, neuronal survival and responses to stress conditions while in L-CO these communities harbor several genes related to pro-epileptic effects, seizure-related mechanisms and vulnerability to epilepsy. These results fit the concept, based on fMRI and behavioral studies, that early onset epilepsies, although impacting more severely the hippocampus, are associated to compensatory mechanisms, while in late MTLE development the brain is less

  8. An Analysis on Geographical Factors for Xi’ an as Historical Capital%历史时期西安为都之地理因素探析

    Institute of Scientific and Technical Information of China (English)

    李舒

    2016-01-01

    古都西安之所以能够长期为都,皆有赖于其自然地理及人文地理方面的优势。其气候、土壤、物产及地形地势等自然地理方面的优势与涵盖历史时期的奠基、政治、经济、交通和思想文化等人文地理方优势共同作用,相辅相成,奠定了西安不可撼动的大古都地位。%Ancient Xi’ an can be chosen as capital city by many dynasties because of its natural geographical advantages .In addition , the human geographical factors , such as the historical heritage,politics,economy,transportation,and ideological culture,also contribute to its capital city position .

  9. Analysis of the relationships between esophageal cancer cases and climatic factors using a Geographic Information System (GIS): a case study of Ardabil province in Iran.

    Science.gov (United States)

    Ahari, Saeid Sadeghieh; Agdam, Fridoon Babaei; Amani, Firouz; Yazdanbod, Abbas; Akhghari, Leyla

    2013-01-01

    Esophageal cancer is a mjaor health problems in many parts of the world. A geographical information system (GIS) allows investigation of the geographical distribution of diseases. The purpose of the present study was to explore the relationship between esophageal cancer and effective climatic factors using GIS. The dispersion distribution and the relationship between environmental factors effective on cancer were measured using Arc GIS. The highest degree of spread was in Germi town and the least was in Ardabil city. There was a significant relationship between effective environmental factors and esophageal cancer in Ardabil province. The results indicated that environmental factors probably are influential in determining the incidence of esophageal cancer. Also, these results can be considered as a window to future comprehensive research on esophageal cancer and related risk factors.

  10. Childhood trauma and childhood urbanicity in relation to psychotic disorder

    NARCIS (Netherlands)

    Frissen, Aleida; Lieverse, Ritsaert; Drukker, Marjan; van Winkel, Ruud; Delespaul, Philippe; Cahn, W

    2015-01-01

    BACKGROUND: Urban upbringing and childhood trauma are both associated with psychotic disorders. However, the association between childhood urbanicity and childhood trauma in psychosis is poorly understood. The urban environment could occasion a background of social adversity against which any effect

  11. Temporal Trends in Geographical Variation in Breast Cancer Mortality in China, 1973–2005: An Analysis of Nationwide Surveys on Cause of Death

    Directory of Open Access Journals (Sweden)

    Changfa Xia

    2016-09-01

    Full Text Available To describe geographical variation in breast cancer mortality over time, we analysed breast cancer mortality data from three retrospective national surveys on causes of death in recent decades in China. We first calculated the age-standardized mortality rate (ASMR for each of the 31 provinces in mainland China stratified by survey period (1973–1975, 1990–1992 and 2004–2005. To test whether the geographical variation in breast cancer mortality changed over time, we then estimated the rate ratio (RR for the aggregated data for seven regions and three economic zones using generalized linear models. Finally, we examined the correlation between mortality rate and several macro-economic measures at the provincial level. We found that the overall ASMR increased from 2.98 per 100,000 in 1973–1975 to 3.08 per 100,000 in 1990–1992, and to 3.85 per 100,000 in 2004–2005. Geographical variation in breast cancer mortality also increased significantly over time at the regional level (p = 0.002 but not at the economic zone (p = 0.089 level, with RR being generally lower for Western China (Northwest and Southwest and higher in Northeast China over the three survey periods. These temporal and spatial trends in breast cancer mortality were found to be correlated with per capita gross domestic product, number of hospitals and health centres’ beds per 10,000 population and number of practicing doctors per 10,000 population, and average number of live births for women aged 15–64. It may be necessary to target public health policies in China to address the widening geographic variation in breast cancer mortality, and to take steps to ensure that the ease of access and the quality of cancer care across the country is improved for all residents.

  12. Temporal Trends in Geographical Variation in Breast Cancer Mortality in China, 1973–2005: An Analysis of Nationwide Surveys on Cause of Death

    Science.gov (United States)

    Xia, Changfa; Kahn, Clare; Wang, Jinfeng; Liao, Yilan; Chen, Wanqing; Yu, Xue Qin

    2016-01-01

    To describe geographical variation in breast cancer mortality over time, we analysed breast cancer mortality data from three retrospective national surveys on causes of death in recent decades in China. We first calculated the age-standardized mortality rate (ASMR) for each of the 31 provinces in mainland China stratified by survey period (1973–1975, 1990–1992 and 2004–2005). To test whether the geographical variation in breast cancer mortality changed over time, we then estimated the rate ratio (RR) for the aggregated data for seven regions and three economic zones using generalized linear models. Finally, we examined the correlation between mortality rate and several macro-economic measures at the provincial level. We found that the overall ASMR increased from 2.98 per 100,000 in 1973–1975 to 3.08 per 100,000 in 1990–1992, and to 3.85 per 100,000 in 2004–2005. Geographical variation in breast cancer mortality also increased significantly over time at the regional level (p = 0.002) but not at the economic zone (p = 0.089) level, with RR being generally lower for Western China (Northwest and Southwest) and higher in Northeast China over the three survey periods. These temporal and spatial trends in breast cancer mortality were found to be correlated with per capita gross domestic product, number of hospitals and health centres’ beds per 10,000 population and number of practicing doctors per 10,000 population, and average number of live births for women aged 15–64. It may be necessary to target public health policies in China to address the widening geographic variation in breast cancer mortality, and to take steps to ensure that the ease of access and the quality of cancer care across the country is improved for all residents. PMID:27690073

  13. Innovation Determinants and Barriers: A Tri-Perspective Analysis of IT Appropriation within an Early Childhood Education and Care Organisation

    Directory of Open Access Journals (Sweden)

    Melinda Plumb

    2015-11-01

    Full Text Available Empirical studies on information technology (IT in early childhood education and care organisations are scant, despite an increasing number of these organisations choosing to innovate with IT. This paper presents a framework to understand the appropriation of IT as an innovation within such an organisation. The framework consists of three perspectives on innovation: an individualist, a structuralist and an interactive process perspective. While the first focuses on concepts such as leadership, IT champions, previous IT exposure, the second focuses on organisation size, parents as stakeholders, competitors, government compliance and regulatory requirements. The third perspective views the innovation as a dynamic phenomenon of change, produced by the continuous interaction of the innovation content, its context, and the appropriation process as related in an interactive process. We demonstrate the framework’s applicability and determine that the three perspectives supplement each other and together provide a deeper understanding of the IT appropriation process in terms of innovation determinants and barriers.

  14. Understanding the Health Behaviors of Survivors of Childhood and Young-Adult Cancer: Preliminary Analysis and Model Development

    Directory of Open Access Journals (Sweden)

    Stefanie C. Vuotto

    2015-05-01

    Full Text Available The current study presents preliminary correlational data used to develop a model depicting the psychosocial pathways that lead to the health behaviors of survivors of childhood and young-adult cancer. Data collected from a sample of 18- to 30-year-old cancer survivors (n = 125 was used to examine the relations among interpersonal support and nonsupport, personal agency, avoidance, depressive symptoms and self-efficacy as they related to health behaviors. The outcome measures examined included tobacco and alcohol use, diet, exercise, sunscreen use, medication compliance and follow-up/screening practices. Correlational analyses revealed a number of significant associations among variables. Results are used to inform the development of a health behavior model. Implications for health promotion and survivorship programming are discussed, as well as directions for future research.

  15. Utilidad del análisis geográfico en el estudio de las muertes por atropellamiento Geographic analysis of pedestrian run-over injuries

    Directory of Open Access Journals (Sweden)

    Martha C. Híjar-Medina

    2000-06-01

    Full Text Available OBJETIVO: Plantear la utilidad de aplicar el análisis geográfico en el estudio de las muertes provocadas por atropellamiento. MATERIAL Y MÉTODOS: Se realizó un estudio transversal, en el año 2000, sobre mortalidad por atropellamiento, de acuerdo con la IX Revisión de la Clasificación Internacional de Enfermedades. Se analizaron certificados de defunción de personas que vivían y fallecieron en la ciudad de México, Distrito Federal, de 1994 a 1997, debido a un atropellamiento. Se calcularon tasas crudas de mortalidad por delegación política y por sexo, asimismo se generaron mapas que contienen las correferencias de las muertes, a distintos grados de agregación, utilizando el programa Map-Info. RESULTADOS: Del total de 3 687 defunciones por atropellamiento, 71% correspondieron a personas que vivían en la ciudad de México. Sólo se incluyeron en el proceso de georreferencia 1 152 defunciones (43.5% que eran las que contaban con información referente al sitio de ocurrencia del atropellamiento. Los resultados, según nivel de agregación, fueron, a nivel delegación política: Milpa Alta, Cuajimalpa y Cuauhtémoc, con tasas por arriba de 23/100 000 habitantes; a nivel colonia, 10 presentan concentraciones de nueve y más casos, y a nivel calle, destaca un punto ubicado en La Venta, en Cuajimalpa, con 25 defunciones. CONCLUSIONES: Este tipo de análisis es fundamental desde las perspectivas espacial y epidemiológica al relacionar algunos factores espaciales que coadyuvan en la ocurrencia de atropellamientos. Estos estudios contribuyen al conocimiento y prevención de las muertes por atropellamiento.OBJECTIVE: The purpose of this paper is to demonstrate the usefulness of geographic analysis to assess the distribution of fatal pedestrian run-over injuries. MATERIAL AND METHODS: Cross-sectional study of mortality due to pedestrian run-over injuries was conducted in year 2000. Data were abstracted from death certificates of pedestrians who

  16. Spatiotemporal Pattern of PM2.5 Concentrations in Mainland China and Analysis of Its Influencing Factors using Geographically Weighted Regression

    Science.gov (United States)

    Luo, Jieqiong; Du, Peijun; Samat, Alim; Xia, Junshi; Che, Meiqin; Xue, Zhaohui

    2017-01-01

    Based on annual average PM2.5 gridded dataset, this study first analyzed the spatiotemporal pattern of PM2.5 across Mainland China during 1998–2012. Then facilitated with meteorological site data, land cover data, population and Gross Domestic Product (GDP) data, etc., the contributions of latent geographic factors, including socioeconomic factors (e.g., road, agriculture, population, industry) and natural geographical factors (e.g., topography, climate, vegetation) to PM2.5 were explored through Geographically Weighted Regression (GWR) model. The results revealed that PM2.5 concentrations increased while the spatial pattern remained stable, and the proportion of areas with PM2.5 concentrations greater than 35 μg/m3 significantly increased from 23.08% to 29.89%. Moreover, road, agriculture, population and vegetation showed the most significant impacts on PM2.5. Additionally, the Moran’s I for the residuals of GWR was 0.025 (not significant at a 0.01 level), indicating that the GWR model was properly specified. The local coefficient estimates of GDP in some cities were negative, suggesting the existence of the inverted-U shaped Environmental Kuznets Curve (EKC) for PM2.5 in Mainland China. The effects of each latent factor on PM2.5 in various regions were different. Therefore, regional measures and strategies for controlling PM2.5 should be formulated in terms of the local impacts of specific factors.

  17. Geographic Disparity in Funding for School Nutrition Environments: Evidence from Mississippi Schools

    Science.gov (United States)

    Chang, Yunhee; Carithers, Teresa; Leeke, Shannon; Chin, Felicia

    2016-01-01

    Background: Despite the federal initiatives on equitable provision of school nutrition programs, geographic disparity in childhood obesity persists. It may be partly because built-in school nutrition environments rely on each school's efficient use of existing operational funds or its ability to obtain expanded financial support. This study…

  18. Averting the legacy of kidney disease - Focus on childhood

    Directory of Open Access Journals (Sweden)

    Julie R Ingelfinger

    2016-01-01

    Full Text Available World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early or who are small-for date newborns have relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely in order to help detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults, if they receive kidney replacement therapy including dialysis and transplantation, while only a minority of children may require this ultimate intervention Because there are disparities in access to care, effort is needed so that those children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic or economic circumstances. Our hope is that World Kidney Day will inform the general public, policy makers and caregivers about the needs and possibilities surrounding kidney disease in childhood.

  19. Averting the legacy of kidney disease--focus on childhood

    Directory of Open Access Journals (Sweden)

    Julie R Ingelfinger

    2016-03-01

    Full Text Available World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early or who are small-for date newborns have relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely in order to help detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults, if they receive kidney replacement therapy including dialysis and transplantation, while only a minority of children may require this ultimate intervention Because there are disparities in access to care, effort is needed so that those children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic or economic circumstances. Our hope is that World Kidney Day will inform the general public, policy makers and caregivers about the needs and possibilities surrounding kidney disease in childhood.

  20. Averting the legacy of kidney disease – focus on childhood

    Directory of Open Access Journals (Sweden)

    Julie R. Ingelfinger

    2016-03-01

    Full Text Available World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD in childhood differs from that in adults, as the largest diagnostic group amongst children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertensionand CKD in later childhood or in adult life. Children born early or who are small-for-date newborns have relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely to help to detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults, if they receive kidney replacement therapy including dialysis and transplantation, whilst only a minority of children may require this ultimate intervention. Because there are disparities in access to care, effort is needed so that children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic oreconomic circumstances. Our hope is that World Kidney Day will inform the general public, policymakers and caregivers about the needs and possibilities surrounding kidney disease in childhood.

  1. Averting the legacy of kidney disease - focus on childhood

    Directory of Open Access Journals (Sweden)

    J.R. Ingelfinger

    2016-01-01

    Full Text Available World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD in childhood differs from that in adults, in that the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease as a consequence of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early or who are small-for-date newborns have relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely in order to help detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults, if they receive kidney replacement therapy including dialysis and transplantation, although only a minority of children may require this ultimate intervention. Because there are disparities in access to care, effort is needed so that children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic or economic circumstances. Our hope is that the World Kidney Day will inform the general public, policy makers and caregivers about the needs and possibilities surrounding kidney disease in childhood.

  2. Childhood, experience and performance: first approaches

    Directory of Open Access Journals (Sweden)

    Sandro Vinicius Sales dos Santos

    2014-08-01

    Full Text Available This paper presents and discusses some preliminary results of a Master thesis aimed to examine the experiences of children of four years within a public institution of early childhood education. The study of interpretative character seeks its theoretical basis in the sociology of childhood and childhood pedagogy and child education. From the methodological point of view, the research is based on a case study (ANDREW, 1991; SARMENTO, 2003 assuming a logic of ethnographic research (NUT, 2004; GREEN, DIXON, ZAHALIRICK, 2005, the main data collection instruments data, participant observation, photographs and drawings articulated with orality; Interviews with children, among others. It also discusses the notion of childhood experience as the possibility of analysis of the forms of sociability of children

  3. Coloring geographical threshold graphs

    Energy Technology Data Exchange (ETDEWEB)

    Bradonjic, Milan [Los Alamos National Laboratory; Percus, Allon [Los Alamos National Laboratory; Muller, Tobias [EINDHOVEN UNIV. OF TECH

    2008-01-01

    We propose a coloring algorithm for sparse random graphs generated by the geographical threshold graph (GTG) model, a generalization of random geometric graphs (RGG). In a GTG, nodes are distributed in a Euclidean space, and edges are assigned according to a threshold function involving the distance between nodes as well as randomly chosen node weights. The motivation for analyzing this model is that many real networks (e.g., wireless networks, the Internet, etc.) need to be studied by using a 'richer' stochastic model (which in this case includes both a distance between nodes and weights on the nodes). Here, we analyze the GTG coloring algorithm together with the graph's clique number, showing formally that in spite of the differences in structure between GTG and RGG, the asymptotic behavior of the chromatic number is identical: {chi}1n 1n n / 1n n (1 + {omicron}(1)). Finally, we consider the leading corrections to this expression, again using the coloring algorithm and clique number to provide bounds on the chromatic number. We show that the gap between the lower and upper bound is within C 1n n / (1n 1n n){sup 2}, and specify the constant C.

  4. A comparative analysis of the clotting and fibrinolytic activities of the snake venom (Bothrops atrox) from different geographical areas in Venezuela.

    Science.gov (United States)

    Salazar, Ana Maria; Rodriguez-Acosta, Alexis; Girón, Maria E; Aguilar, Irma; Guerrero, Belsy

    2007-01-01

    Venom constitution within the same snake species can present considerable geographical variations. Bothrops atrox venoms were obtained from adult snakes captured at different geographical locations: Parguasa (Bolívar state); Puerto Ayacucho 1, Serranía del Cuao and Puerto Ayacucho 2 (Amazon state). The coagulant and fibrinolytic activities of these venoms were compared. Amidolytic activity of crude snake venom was measured by a micromethod designed in our laboratory. Coagulant activity on plasma and fibrinogen due to thrombin-like activity in venoms was also determined. Crude snake venom fibrinolytic activity by the fibrin plate method was assayed. Chromatographic studies were developed on Protein-Pack 300 column. Polyacrylamide gel electrophoresis was carried out under reduced conditions. After SDS-PAGE of samples, the fibrin-zymography was tested on agarose-fibrin plates. The results demonstrated several differences among B. atrox venoms from different geographical areas. Chromatograms and SDS-PAGE profiles indicated that venoms from the same species presented differences in the molecular mass of their components. The procoagulant activity depended on the utilized method (amidolytic versus clotting). Parguasa and Puerto Ayacucho 2 venoms presented procoagulant activity for both methods. Furthermore, Parguasa venom had also the highest hemorrhagic activity and the lowest LD50. In relation to the fibrinolytic activity, Puerto Ayacucho 1 venom was the most active, equally for fibrin plates as for the amidolytic method (t-PA like). This venom had the lowest coagulant activity, which induced us to think that probably its procoagulant activity was interfered by its fibrinolytic activity.

  5. International Refugees: A Geographical Perspective.

    Science.gov (United States)

    Demko, George J.; Wood, William B.

    1987-01-01

    Examines the problem of international refugees from a geographical perspective. Focuses on sub-saharan Africa, Afghanistan, Central America, and southeast Asia. Concludes that geographers can and should use their skills and intellectual tools to address and help resolve this global problem. (JDH)

  6. Teaching Poverty with Geographic Visualization and Geographic Information Systems (GIS): A Case Study of East Buffalo and Food Access

    Science.gov (United States)

    Gjesfjeld, Christopher D.; Jung, Jin-Kyu

    2014-01-01

    Although various methods have been used to teach about poverty in the social work classroom (e.g., quantitative, historical, and qualitative), the use of geographic visualization and geographic information systems (GIS) has become a relatively new method. In our analysis of food access on the East Side of Buffalo, New York, we demonstrate the…

  7. 地勘单位人力资源管理工作浅析%Analysis of the Human Resources Management in the Geographical Explosion Organization

    Institute of Scientific and Technical Information of China (English)

    王树滨

    2011-01-01

    recently,the problems that exist in all the geographical exploration are that the organization is overstaffed,the product equipments and techniques fell behind,incentive mechanism is inadequate,and talents seriously drain.In order to really strengthen enterprise management,the geographical exploration organization should form people-oriental management philosophy,establish a pleasure working atmosphere,reinforce the building of human resources management team and improve the human resources management.%现阶段,各地勘单位存在的共性问题是人浮于事,生产设备、技术落后,激励机制不够完善,人才流失严重。地勘单位真正强化企业管理,必须树立以人为本的经营理念,建立良好的工作氛围,加强人才资源管理队伍的建设,提高人才资源管理水平。

  8. Childhood Roots of Schizophrenia

    Science.gov (United States)

    Watt, Norman F.; Lubensky, Amy W.

    1976-01-01

    Earlier project reports compared childhood social behavior of nonmigratory schizophrenics and normal classmates by analyzing teachers' comments in school records. This article expands the sample to include migratory schizophrenics and analyzes childhood intellectual functioning. Behavioral differences indicated emotional immaturity and social…

  9. Childhood Overweight and Obesity

    Science.gov (United States)

    ... Home Prevention and Wellness Food and Nutrition Healthy Food Choices Childhood Overweight and Obesity Childhood Overweight and Obesity Family HealthFood and NutritionHealthy Food ChoicesKids and TeensPrevention and WellnessWeight Loss and Diet ...

  10. Undiagnosed asthma in childhood

    NARCIS (Netherlands)

    van Gent, R.

    2008-01-01

    Asthma is the most prevalent chronic disease in childhood. To study the actual prevalence and impact of undiagnosed childhood asthma in daily life (i.e. quality of life, participation in physical and school activities) we performed a survey in schoolchildren (aged 7-10 years) in the southern part of

  11. Geographical Clustering of Juvenile Onset Systemic Lupus Erythematosus within the Sultanate of Oman

    Directory of Open Access Journals (Sweden)

    Ibrahim Al-Zakwani

    2013-05-01

    Full Text Available Objective: While SLE is found worldwide, there is diversity in clinical presentation of the disease according to geographical variations. The aim of this study is to describe geographical distributions of childhood onset SLE within Oman to identify geographical clustering and to compare the demographic, clinical, and immunological characteristics of this cluster against the rest of Oman.Methods: We retrospectively reviewed the hospital charts of 104 consecutive children with childhood onset SLE who were seen in pediatric rheumatology centers in the Sultanate of Oman over a 15-year period between 1995 and 2010.Results: Geographical clustering of childhood onset SLE was identified in Sharqiya region, which constituted 41% (n=43 of all cases in Oman. This cohort of patients had characteristic disease features which consisted of significantly more boys affected with SLE compared to the rest of the country (42% versus 15%; p=0.002. These children also tended to be younger (10.3 versus 16.5 years; p=0.001, diagnosed at an earlier age (6.4 versus 9.4 years; p<0.001 with a stronger family history of SLE (58% versus 33%; p=0.010. These children also had increased incidence of mucocutanous changes (81% versus 62%; p=0.036 and decreased hematological abnormalities (30% versus 51%; p=0.036.Conclusion: We identified geographical clustering of childhood onset SLE to Sharqiya region in Oman which is associated with unique demographical and clinical features. Whether increased prevalence of disease in this region is due to geographical, environmental, ethnic or genetic factors is yet to be determined. However, it is likely to be interplay of known and other unrecognized factors.

  12. Maternal Employment and Childhood Obesity

    DEFF Research Database (Denmark)

    Gwozdz, Wencke; Sousa-Poza, Alfonso; Reisch, Lucia

    The substantial increase in female employment rates in Europe over the past two decades has often been linked in political and public rhetoric to negative effects on child development, including obesity. We analyse this association between maternal employment and childhood obesity using rich...... objective reports of various anthropometric and other measures of fatness from the IDEFICS study of children aged 2-9 in 16 regions of eight European countries. Based on such data as accelerometer measures and information from nutritional diaries, we also investigate the effects of maternal employment...... on obesity's main drivers: calorie intake and physical activity. Our analysis provides little evidence for any association between maternal employment and childhood obesity, diet or physical activity....

  13. Maternal Employment and Childhood Obesity

    DEFF Research Database (Denmark)

    Gwozdz, Wencke; Sousa-Poza, Alfonso; Reisch, Lucia

    2013-01-01

    The substantial increase in female employment rates in Europe over the past two decades has often been linked in political and public rhetoric to negative effects on child development, including obesity. We analyse this association between maternal employment and childhood obesity using rich...... objective reports of various anthropometric and other measures of fatness from the IDEFICS study of children aged 2-9 in 16 regions of eight European countries. Based on such data as accelerometer measures and information from nutritional diaries, we also investigate the effects of maternal employment...... on obesity's main drivers: calorie intake and physical activity. Our analysis provides little evidence for any association between maternal employment and childhood obesity, diet or physical activity....

  14. Relationship between household wealth inequality and chronic childhood under-nutrition in Bangladesh

    Directory of Open Access Journals (Sweden)

    Betancourt Jose A

    2006-12-01

    Full Text Available Abstract Background Household food insecurity and under-nutrition remain critically important in developing countries struggling to emerge from the scourge of poverty, where historically, improvements in economic conditions have benefited only certain privileged groups, causing growing inequality in health and healthcare among the population. Methods Utilizing information from 5,977 children aged 0-59 months included in the 2004 Bangladesh Demographic and Health Survey , this study examined the relationship between household wealth inequality and chronic childhood under-nutrition. A child is defined as being chronically undernourished or whose growth rate is adversely stunted, if his or her z-score of height-for-age is more than two standard deviations below the median of international reference. Household wealth status is measured by an established index based on household ownership of durable assets. This study utilized multivariate logistic regressions to estimate the effect of household wealth status on adverse childhood growth rate. Results The results indicate that children in the poorest 20% of households are more than three time as likely to suffer from adverse growth rate stunting as children from the wealthiest 20% of households (OR=3.6; 95% CI: 3.0, 4.3. The effect of household wealth status remain significantly large when the analysis was adjusted for a child's multiple birth status, age, gender, antenatal care, delivery assistance, birth order, and duration that the child was breastfed; mother's age at childbirth, nutritional status, education; household access to safe drinking water, arsenic in drinking water, access to a hygienic toilet facility, cooking fuel cleanliness, residence, and geographic location (OR=2.4; 95% CI: 1.8, 3.2. Conclusion This study concludes that household wealth inequality is strongly associated with childhood adverse growth rate stunting. Reducing poverty and making services more available and accessible

  15. Application of a geographical information system approach for risk analysis of fascioliasis in southern Espírito Santo state, Brazil.

    Science.gov (United States)

    Martins, Isabella Vilhena Freire; de Avelar, Barbara Rauta; Pereira, Maria Julia Salim; da Fonseca, Adevair Henrique

    2012-09-01

    A model based on geographical information systems for mapping the risk of fascioliasis was developed for the southern part of Espírito Santo state, Brazil. The determinants investigated were precipitation, temperature, elevation, slope, soil type and land use. Weightings and grades were assigned to determinants and their categories according to their relevance with respect to fascioliasis. Theme maps depicting the spatial distribution of risk areas indicate that over 50% of southern Espírito Santo is either at high or at very high risk for fascioliasis. These areas were found to be characterized by comparatively high temperature but relatively low slope, low precipitation and low elevation corresponding to periodically flooded grasslands or soils that promote water retention.

  16. The New and Computationally Efficient MIL-SOM Algorithm: Potential Benefits for Visualization and Analysis of a Large-Scale High-Dimensional Clinically Acquired Geographic Data

    Directory of Open Access Journals (Sweden)

    Tonny J. Oyana

    2012-01-01

    Full Text Available The objective of this paper is to introduce an efficient algorithm, namely, the mathematically improved learning-self organizing map (MIL-SOM algorithm, which speeds up the self-organizing map (SOM training process. In the proposed MIL-SOM algorithm, the weights of Kohonen’s SOM are based on the proportional-integral-derivative (PID controller. Thus, in a typical SOM learning setting, this improvement translates to faster convergence. The basic idea is primarily motivated by the urgent need to develop algorithms with the competence to converge faster and more efficiently than conventional techniques. The MIL-SOM algorithm is tested on four training geographic datasets representing biomedical and disease informatics application domains. Experimental results show that the MIL-SOM algorithm provides a competitive, better updating procedure and performance, good robustness, and it runs faster than Kohonen’s SOM.

  17. Analysis of factors influencing the overall effect of racecadotril on childhood acute diarrhea. Results from a real-world and post-authorization surveillance study in Venezuela

    Directory of Open Access Journals (Sweden)

    Jose Chacón

    2010-06-01

    Full Text Available Jose ChacónOn behalf of the Racecadotril Post-authorization Record Group; Centro Clinico Profesional Caracas, Caracas, VenezuelaAbstract: Drug efficacy might differ from clinical trial results when performed in clinical daily conditions. Therefore, it is mandatory to conduct trials about effectiveness to improve external validity. This post-authorization, open-label, noncontrolled, prospective, multicenter, observational, and naturalistic trial was designed to search for factors influencing the racecadotril overall effect on childhood acute watery diarrhea in a real-world setting of Venezuela. There were 3,873 children with acute watery diarrhea treated with racecadotril, an enkephalin breakdown blocker plus oral rehydration therapy by 97 pediatricians. Evaluations were carried out daily until emission of two consecutive formed stools or absence of watery bowel movements for 24 hours. The primary end-point was time-to-relief, defined as the time from first racecadotril dose to the last watery bowel movement time. Age, gender, nursing type, nursing status during diarrhea, diarrhea severity, and co-medication were considered as factors in the statistical analysis. The primary end-point was evaluated by factors using UNIANOVA, and post-hoc tests were done. A multiple regression analysis was carried out to identify factors affecting drug performance, racecadotril effectiveness and tolerability overall assessment was searched by physicians and patients, and inter-observer agreement was evaluated by kappa statistics. The mean time-to-relief was 18.5 ± 12.5 hours [95% confidence interval 17.9–19.0] and the diarrhea severity was the only variable with significant and independent weight on racecadotril effectiveness explaining 23% of time-to-relief variance, but even in severe diarrhea cases this time was less than 24 hours. High agreement about satisfactory perception on effectiveness and tolerability was reached among physicians and patients. In

  18. Gender and geographic differences in the prevalence of intellectual disability in children: analysis of data from the national disability registry of Taiwan.

    Science.gov (United States)

    Lai, Der-Chung; Tseng, Yen-Cheng; Hou, Yuh-Ming; Guo, How-Ran

    2012-01-01

    Intellectual disability (ID) is not uncommon in children, but data at the national level are limited, especially those on geographic differences. On the basis of the Disabled Welfare Law, Taiwan began to certify disabled residents and provide various services in 1980. All the cases are registered, and the registry provides a rare opportunity for studying ID at the national level. Using the data from 2004 to 2010, we calculated the prevalence of ID in children by age, gender, and geographic area and assessed the changes over time. We limited analyses to children at least 3 years of age, because certification before 3 years old is discouraged by the government. We found that from 2004 to 2010, the registered cases between 3 and 17 years old ranged from 20,531 to 23,547, and the prevalence of ID increased constantly from 4.40/1000 to 5.79/1000 (p<0.01), which generally increased every year in all age groups (p<0.01). In each year there were more boy cases than girl cases, and the boy-to-girl ratio generally decreased with age (p<0.01 for chi-square test for trend in all years). The prevalence rate ratio ranged from 1.33 to 1.37 (p<0.01 in all years), and the changes in the rate ratio were small over the years. We observed a higher prevalence in the rural areas over the years, and the prevalence rate ratio ranged from 1.34 to 1.43 (p<0.01 in all years), with an increasing trend over time (p<0.01).

  19. Geographical Effects on Complex Networks

    Institute of Scientific and Technical Information of China (English)

    LIN Zhong-Cai; YANG Lei; YANG Kong-Qing

    2005-01-01

    @@ We investigate how the geographical structure of a complex network affects its network topology, synchronization and the average spatial length of edges. The geographical structure means that the connecting probability of two nodes is related to the spatial distance of the two nodes. Our simulation results show that the geographical structure changes the network topology. The synchronization tendency is enhanced and the average spatial length of edges is enlarged when the node can randomly connect to the further one. Analytic results support our understanding of the phenomena.

  20. Typicity in Potato: Characterization of Geographic Origin

    Directory of Open Access Journals (Sweden)

    Marco Manzelli

    2010-03-01

    Full Text Available A two-year study was carried out in three regions of Italy and the crop performance and the chemical composition of tubers of three typical potato varieties evaluated. Carbon and nitrogen tuber content was determined by means of an elemental analyzer and the other mineral elements by means of a spectrometer. The same determinations were performed on soil samples taken from experimental areas. The Principal Component Analysis, applied to the results of mineral element tuber analysis, permitted the classification of all potato tuber samples according to their geographic origin. Only a partial discrimination was obtained in function of potato varieties. Some correlations between mineral content in the tubers and in the soil were also detected. Analytical and statistical methods proved to be useful in verifying the authenticity of guaranteed geographical food denominations.

  1. Trends in Demography of Childhood Poverty and Disability.

    Science.gov (United States)

    Fujiura, Glenn T.; Yamaki, Kiyoshi

    2000-01-01

    This article presents childhood disability prevalence trends and their interaction with economic status. Estimates derived from National Health Interview Survey data (1983-96) indicate a significant increase in childhood disability rates. Analysis indicates a greater risk in single-parent households and a growing relationship between poverty and…

  2. Early Childhood Socialization: Societal Context and Childrearing Values in Hungary

    Science.gov (United States)

    Brayfield, April; Korintus, Marta

    2011-01-01

    This article examines the socio-cultural context of early childhood socialization in Hungary. Using a macroscopic lens, we describe the national demographic situation and the social organization of early childhood education and care. Our analysis then shifts to a microscopic focus on parental values and beliefs about the substance of what young…

  3. 33 CFR 165.8 - Geographic coordinates.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Geographic coordinates. 165.8... Geographic coordinates. Geographic coordinates expressed in terms of latitude or longitude, or both, are not... 1983 (NAD 83), unless such geographic coordinates are expressly labeled NAD 83. Geographic...

  4. Soil Survey Geographic (SSURGO) database for Union County, New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

  5. Soil Survey Geographic (SSURGO) database for Roosevelt County, New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

  6. Soil Survey Geographic (SSURGO) database for Otero Area, New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

  7. Soil Survey Geographic (SSURGO) database for Guadalupe County, New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

  8. Soil Survey Geographic (SSURGO) database for Colfax County, New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

  9. Soil Survey Geographic (SSURGO) database for Harding County, New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

  10. Soil Survey Geographic (SSURGO) database for Lea County, New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

  11. Soil Survey Geographic (SSURGO) database for Hidalgo County, New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

  12. Soil Survey Geographic (SSURGO) database for Torrance Area, New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

  13. Soil Survey Geographic (SSURGO) database for Eddy Area, New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

  14. Soil Survey Geographic (SSURGO) database for Luna County, New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a digital soil survey and generally is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The...

  15. Operation and design of gas pipeline with cross geographical areas with big altitude changes: importance of the dynamic analysis; Diseno y operacion de gasoductos en zonas de elevadas diferencias altimetricas: importancia del analisis dinamico

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez, Oscar [Transportadora de Gas del Norte S.A. (Argentina)

    2003-07-01

    The Natural Gas Demand has increased constantly in the last decades. It was mainly due to the discovery of enormous gas reserves, the opening of the energetic markets and its utilization as fuel for power generation The supply of new markets in Latin America has meant the development of several interconnection projects among countries. The development of projects crossing the Andes Mountains, with big altitude differences, impose new requirements for the design and pipeline operation The purpose of this paper is to continue the analysis of the gas pipeline modeling methods which cross geographical areas with big altitude changes, specifically under the dynamic point of view In these cases, the operating parameters are strongly linked to the analysis and comprehension of transient phenomenon and consequently an efficient line pack management. The demand suing is fundamental when systems crossing this kind of geographical areas are designed and operated The design should consider the response time, having capacity to support a demand variation. Finally the impact in the commercial operation of this phenomenon is analyzed, due to the possibility to detect idle capacity or optimize solutions, reducing investment and assurance an operation without risks. Thus in the design period , the capability of bringing a reliability service at a reduced cost is emphasized in benefit of the customers. (author)

  16. Geographic information system(GIS) applications to optimize route selection, environmental analysis and power transmission line designs; Aplicaciones en sistemas de informacion geograficos (SIG) para optimizar seleccion de ruta, analisis ambiental y diseno de lineas de transmision

    Energy Technology Data Exchange (ETDEWEB)

    Cadena Suarez, Luis Fernando; Posada Delgado, Fabio Humberto; Alvarez Davila, Esteban; Gomez Colorado, Oscar Alberto [Interconexion Electrica S.A. (ISA), Medellin (Colombia)]. E-mail: fecadena@isa.com.co

    2001-07-01

    Interconexion Eletrica s.a. (ISA) is a company of the Colombian government for electric energy transportation through the national energy transportation network, it makes part of the companies group with growing environmental conscience. The better route identifications for high voltage transmission lines do not involve just the engineering analyses, but mainly the environmental one.These integrated analysis have been largely powered through the technology applications like Geographic Information Systems (GIS) and Remote Sensing (RS). These technologies were applied for a total of 300 kilometers between 1992 and 2000 in the largest power transmission lines whose configurations cross different geographic conditions. This current technical contribution describes the application of GIS and RS technologies for the best routes, environmental sensibility analysis and environmental impact evaluations. The applications have resulted in the integration between engineering and environmental processes, optimization of environmental evaluation, formulations of procedures handling and environmental control, as well as transmission line profile characteristics. After the project construction, GIS can be used as a useful tool for environmental monitoring in connection with power transmission lines, maintenance of servitude areas, availability conditions and quality of the high voltage transmission service.

  17. Constructing Childhood: Discourses about School Violence in the Greek Daily Press

    Science.gov (United States)

    Avgitidou, Sofia; Stamou, Anastasia G.

    2013-01-01

    This study explores the construction of discourses about childhood in the Greek daily press. It employs the theoretical frameworks of the new sociology of childhood and critical discourse analysis to question which discourses of childhood are constructed in the daily press presenting cases where children were the victimisers in school violent…

  18. Ecoscapes: Geographical Patternings of Relations

    Directory of Open Access Journals (Sweden)

    Aimar Ventsel

    2012-06-01

    Full Text Available Book review of the publication Ecoscapes: Geographical Patternings of Relations. Edited by Gary Backhaus and John Murungi. Lanham, Boulder, New York, Toronto, Oxford, Lexington Books, 2006, xxxiii+241 pp.

  19. NEPR Geographic Zone Map 2015

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This geographic zone map was created by interpreting satellite and aerial imagery, seafloor topography (bathymetry model), and the new NEPR Benthic Habitat Map...

  20. Gender moderates the relationship between childhood abuse and internalizing and substance use disorders later in life: a cross-sectional analysis

    OpenAIRE

    Meng, Xiangfei; D’Arcy, Carl

    2016-01-01

    Background Although some studies examined the moderating role of gender in the relationship between childhood maltreatment and mental disorders later in life, a number of them examined the effects of only one or two types of maltreatment on an individual mental disorder, for instance, depression, substance use. It is of considerable clinical and theoretical importance to have in-depth understanding what roles of different types of childhood abuse play out in a wide range of mental disorders a...

  1. Geographic Tongue in Monozygotic Twins

    OpenAIRE

    Shekhar M, Guna

    2014-01-01

    This article discusses a case of 5-year-old girl monozygotic twins who were suffering from geographic tongue (GT), a benign inflammatory disorder of the tongue which is characterized by circinate, irregular erythematous lesions on the dorsum and lateral borders of the tongue caused by loss of filiform papillae of the tongue epithelium. Whilst geographic tongue is a common entity, reports on this condition are uncommon in the literature. To best of our knowledge, this is the first report which...

  2. Analysis of epidemiological investigation and prevention of childhood asthma%儿童哮喘流行病学及防治现状探析

    Institute of Scientific and Technical Information of China (English)

    孔涛

    2014-01-01

    Objective: To investigate the epidemiology, distribution feature and influencing factors of asthma in order to provide epidemiology evidence for asthma management. Methods 5600 children aged 0~14 years old with bronchial asthma in Laiwu City were investigated in order to explore the risk factors of childhood asthma. Results: The incidence rate of asthma was 4.4%. The incidence rate in male was obviously higher than that of female.The first age of onset of asthma before 3 yeas old was 61.8%.With multivariate Logistic regression analysis showed that 11 risk factors for children asthma included premature birth, cesarean section,a family history of allergy, et al. Breastfeeding is the protective factor. Conclusion: The morbidity rate of asthma in Laiwu City is relatively high. We must control and correct the risk factors of children asthma,which has great significance to prevent and control childhood asthma.%目的:对儿童哮喘的患病情况及其相关影响因素进行流行病学调查,为儿童哮喘的防治策略提供依据。方法:对莱芜市5600名0~14岁的儿童进行儿童哮喘的流行病学调查,分析疾病发生的危险因素。结果:儿童哮喘的患病率为4.4%;其中男孩患病率高于女孩;在哮喘患儿中,首次发病以3岁以内为最多(61.8%);经多因素 Logistic 回归分析,儿童哮喘发病的危险因素有剖宫产,早产,家族过敏史等11个因素,而母乳喂养为哮喘的保护因素。结论:莱芜市儿童哮喘的发病率较高,积极控制发生儿童哮喘的相关危险因素,对儿童哮喘防治有重要意义。

  3. Brief Analysis of the Application of"Digital Shenyang"Fundamental Geographical Database in Geographic Conditions Survey%浅析"数字沈阳"基础地理信息数据库在地理国情普查中的应用

    Institute of Scientific and Technical Information of China (English)

    宋雪驹; 李天; 毛婧一

    2015-01-01

    基础地理信息数据库是数字沈阳地理空间框架的重要成果。最大限度地整合、利用现有的基础地理信息数据对地理国情普查工作有着很重要的意义。本文结合沈阳地理国情普查工作的技术和方法,分别探讨了"数字沈阳"基础地理信息数据在地表覆盖分类和地理国情要素采集中的应用技术,为地理国情普查的内业采集工作提供了思路和方法。%Fundamental geographical database is the important achievement of digital Shenyang geospatial framework. To maximize the integration and utilization of fundamental geographical data of ex-isting have very important meaning for the geographic conditions sur-vey. Combined with the technology and method of Shenyang geograph-ic conditions survey, this paper discusses the application of "digital Shenyang" fundamental geographical data in surface coverage classifi-cation and national geographical conditions elements collection, and provides the ideas and methods for the collection of work within the industry of National Geographic Conditions Survey.

  4. Child-Staff Ratios in Early Childhood Education and Care Settings and Child Outcomes: A Systematic Review and Meta-Analysis

    Science.gov (United States)

    Perlman, Michal; Fletcher, Brooke; Falenchuk, Olesya; Brunsek, Ashley; McMullen, Evelyn; Shah, Prakesh S.

    2017-01-01

    Child-staff ratios are a key quality indicator in early childhood education and care (ECEC) programs. Better ratios are believed to improve child outcomes by increasing opportunities for individual interactions and educational instruction from staff. The purpose of this systematic review, and where possible, meta-analysis, was to evaluate the association between child-staff ratios in preschool ECEC programs and children’s outcomes. Searches of Medline, PsycINFO, ERIC, websites of large datasets and reference sections of all retrieved articles were conducted up to July 3, 2015. Cross-sectional or longitudinal studies that evaluated the relationship between child-staff ratios in ECEC classrooms serving preschool aged children and child outcomes were independently identified by two reviewers. Data were independently extracted from included studies by two raters and differences between raters were resolved by consensus. Searches revealed 29 eligible studies (31 samples). Child-staff ratios ranged from 5 to 14.5 preschool-aged children per adult with a mean of 8.65. All 29 studies were included in the systematic review. However, the only meta-analysis that could be conducted was based on three studies that explored associations between ratios and children’s receptive language. Results of this meta-analysis were not significant. Results of the qualitative systematic review revealed few significant relationships between child-staff ratios and child outcomes construed broadly. Thus, the available literature reveal few, if any, relationships between child-staff ratios in preschool ECEC programs and children’s developmental outcomes. Substantial heterogeneity in the assessment of ratios, outcomes measured, and statistics used to capture associations limited quantitative synthesis. Other methodological limitations of the research integrated in this synthesis are discussed. PMID:28103288

  5. Adverse childhood experiences and health anxiety in adulthood.

    Science.gov (United States)

    Reiser, Sarah J; McMillan, Katherine A; Wright, Kristi D; Asmundson, Gordon J G

    2014-03-01

    Childhood experiences are thought to predispose a person to the development of health anxiety later in life. However, there is a lack of research investigating the influence of specific adverse experiences (e.g., childhood abuse, household dysfunction) on this condition. The current study examined the cumulative influence of multiple types of childhood adversities on health anxiety in adulthood. Adults 18-59 years of age (N=264) completed a battery of measures to assess adverse childhood experiences, health anxiety, and associated constructs (i.e., negative affect and trait anxiety). Significant associations were observed between adverse childhood experiences, health anxiety, and associated constructs. Hierarchical multiple regression analysis indicted that adverse childhood experiences were predictive of health anxiety in adulthood; however, the unique contribution of these experience were no longer significant following the inclusion of the other variables of interest. Subsequently, mediation analyses indicated that both negative affect and trait anxiety independently mediated the relationship between adverse childhood experiences and health anxiety in adulthood. Increased exposure to adverse childhood experiences is associated with higher levels of health anxiety in adulthood; this relationship is mediated through negative affect and trait anxiety. Findings support the long-term negative impact of cumulative adverse childhood experiences and emphasize the importance of addressing negative affect and trait anxiety in efforts to prevent and treat health anxiety.

  6. Neurocognitive Phenotypes in Severe Childhood Psychiatric Disorders.

    Science.gov (United States)

    Kavanaugh, Brian C; Dupont-Frechette, Jennifer A; Tellock, Perrin P; Maher, Isolde D; Haisley, Lauren D; Holler, Karen A

    2016-10-01

    This study investigated the presence of potential neurocognitive phenotypes within a severe childhood psychiatric sample. A medical chart review was conducted for 106 children who received a neuropsychological evaluation during children's psychiatric inpatient program hospitalization. A hierarchical cluster analysis was conducted to identify distinct clinical clusters based on neurocognitive measures. Cluster analysis identified four distinct clusters, subsequently labeled neurocognitive phenotypes: "intact cognition" (27%), "global dysfunction" (20%), "organization/planning" (21%), and "inhibition-memory" (32%). Significant differences were identified in history of legal involvement and antipsychotic medications at hospital admission. Differences between none-minimal and moderate-high neurocognitive dysfunction were identified in age, amount of diagnoses and antipsychotic medications at admission, and hospital length of stay. Current findings provide preliminary evidence of underlying neurocognitive phenotypes within severe childhood psychiatric disorders. Findings highlight the importance of neuropsychological evaluation in the treatment of childhood psychiatric disorders.

  7. Independent Evaluation of the integrated Community Case Management of Childhood Illness Strategy in Malawi Using a National Evaluation Platform Design.

    Science.gov (United States)

    Amouzou, Agbessi; Kanyuka, Mercy; Hazel, Elizabeth; Heidkamp, Rebecca; Marsh, Andrew; Mleme, Tiope; Munthali, Spy; Park, Lois; Banda, Benjamin; Moulton, Lawrence H; Black, Robert E; Hill, Kenneth; Perin, Jamie; Victora, Cesar G; Bryce, Jennifer

    2016-03-01

    We evaluated the impact of integrated community case management of childhood illness (iCCM) on careseeking for childhood illness and child mortality in Malawi, using a National Evaluation Platform dose-response design with 27 districts as units of analysis. "Dose" variables included density of iCCM providers, drug availability, and supervision, measured through a cross-sectional cellular telephone survey of all iCCM-trained providers. "Response" variables were changes between 2010 and 2014 in careseeking and mortality in children aged 2-59 months, measured through household surveys. iCCM implementation strength was not associated with changes in careseeking or mortality. There were fewer than one iCCM-ready provider per 1,000 under-five children per district. About 70% of sick children were taken outside the home for care in both 2010 and 2014. Careseeking from iCCM providers increased over time from about 2% to 10%; careseeking from other providers fell by a similar amount. Likely contributors to the failure to find impact include low density of iCCM providers, geographic targeting of iCCM to "hard-to-reach" areas although women did not identify distance from a provider as a barrier to health care, and displacement of facility careseeking by iCCM careseeking. This suggests that targeting iCCM solely based on geographic barriers may need to be reconsidered.

  8. Childhood vitiligo: Treatment paradigms

    Directory of Open Access Journals (Sweden)

    Amrinder Jit Kanwar

    2012-01-01

    Full Text Available Childhood vitiligo differs from the adults by showing a higher incidence in females, segmental vitiligo being more common and less frequent association with other systemic autoimmune and endocrine disorders.Childhood vitiligo is often associated with a marked psychosocial and long lasting effect on the self-esteem of the affected children and their parents, hence an adequate treatment is very essential. Treatment of vitiligo is indeed a tough challenge for the dermatologists′ more so in the background of childhood vitiligo. Although multiple therapeutic modalities are available in the therapeutic armamentarium, not all can be used in children. This brief report updates regarding various therapies available in the treatment of childhood vitiligo.

  9. Childhood Obesity: Common Misconceptions

    Science.gov (United States)

    ... of childhood obesity. Yes, hypothyroidism (a deficit in thyroid secretion) and other rarer and more severe genetic and metabolic disorders (eg, Prader-Willi syndrome, Turner syndrome, Cushing syndrome) ...

  10. Cardiovascular Conditions of Childhood

    Science.gov (United States)

    ... diagnosed, treated and even cured in younger children. Kawasaki Disease This childhood illness can result in long-term ... complications. Learn the symptoms, diagnosis and treatment for Kawasaki disease. Cholesterol Raised cholesterol levels early in life may ...

  11. Stages of Childhood Craniopharyngioma

    Science.gov (United States)

    ... has any of the following: Headaches, including morning headache or headache that goes away after vomiting . Vision changes. Nausea ... Cancer Late Effects of Treatment for Childhood Cancer Adolescents and Young Adults with Cancer Children with Cancer: ...

  12. Childhood Craniopharyngioma Treatment

    Science.gov (United States)

    ... has any of the following: Headaches, including morning headache or headache that goes away after vomiting . Vision changes. Nausea ... Cancer Late Effects of Treatment for Childhood Cancer Adolescents and Young Adults with Cancer Children with Cancer: ...

  13. Stages of Childhood Rhabdomyosarcoma

    Science.gov (United States)

    ... It may be painful. Bulging of the eye. Headache. Trouble urinating or having bowel movements. Blood in ... Cancer Late Effects of Treatment for Childhood Cancer Adolescents and Young Adults with Cancer Children with Cancer: ...

  14. Childhood Astrocytomas Treatment

    Science.gov (United States)

    ... your child has any of the following: Morning headache or headache that goes away after vomiting . Nausea and vomiting. ... Cancer Late Effects of Treatment for Childhood Cancer Adolescents and Young Adults with Cancer Children with Cancer: ...

  15. Perinatal and Childhood Stroke

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2002-03-01

    Full Text Available The epidemiology, risk factors, outcome and prognosis of perinatal and childhood stroke were reviewed at a workshop sponsored by the National Institute of Neurological Disorders and Stroke in Bethesda, MD, on Sept 18 and 19, 2000.

  16. GEOGRAPHIC INFORMATION SYSTEM-BASED MODELING AND ANALYSIS FOR SITE SELECTION OF GREEN MUSSEL, Perna viridis, MARICULTURE IN LADA BAY, PANDEGLANG, BANTEN PROVINCE

    Directory of Open Access Journals (Sweden)

    I Nyoman Radiarta

    2011-06-01

    Full Text Available Green mussel is one of important species cultured in Lada Bay, Pandeglang. To provide a necessary guidance regarding green mussel mariculture development, finding suitable site is an important step. This study was conducted to identify suitable site for green mussel mariculture development using geographic information system (GIS based models. Seven important parameters were grouped into two submodels, namely environmental (water temperature, salinity, suspended solid, dissolve oxygen, and bathymetry and infrastructural (distance to settlement and pond aquaculture. A constraint data was used to exclude the area from suitability maps that cannot be allowed to develop green mussel mariculture, including area of floating net fishing activity and area near electricity station. Analyses of factors and constraints indicated that about 31% of potential area with bottom depth less than 25 m had the most suitable area. This area was shown to have an ideal condition for green mussel mariculture in this study region. This study shows that GIS model is a powerful tool for site selection decision making. The tool can be a valuable tool in solving problems in local, regional, and/or continent areas.

  17. An Analysis of Urban Land Development Using Multi-Criteria Decision Model and Geographical Information System (A Case Study of Babolsar City

    Directory of Open Access Journals (Sweden)

    Sedigheh Lotfi

    2009-01-01

    Full Text Available Problem Statement: The unplanned physical expansion of cities has been one of the most important problems of urban management in developing countries. Iran, like other developing world has experienced a high level of urbanization growth which transformed the physical fabric of urban areas. North of Iran is one of most rapid growing region of the country where the moderate climate and a tourism based economy encouraged many developers to investigate in housing sector. So, the primary outcome of such process was the out-growth of the city boundaries in the region. Approach: This research attempted to present an appropriate model for urban physical development. The study used different parameters such as environmental and socio-economic factors to provide a good understanding of the city behavior in its geographical setting. Through applying the Multi-Criteria Decision Model (MCDA and GIS, the most appropriate area introduced for near future development. Results: The results revealed that the integrated GIS and MCDA model has many potentials which allow the planner or user investigate the final decision for site selection for future urban physical development. Conclusion: Since the city is located in a fertile agricultural area where the general policy of the local government is to save the lands for strategic crops like rice, to select the right site for city development is quiet significant.

  18. Clustering of cases of type 1 diabetes in high socioeconomic communes in Santiago de Chile: spatio-temporal and geographical analysis.

    Science.gov (United States)

    Torres-Avilés, Francisco; Carrasco, Elena; Icaza, Gloria; Pérez-Bravo, Francisco

    2010-09-01

    The objective of this study was to describe spatial and space-time patterns of type 1 diabetes in children less than 15 years old, diagnosed between 2000 and 2005 with residence in the Metropolitan Region of Chile. Knox and Mantel tests were used to detect space-time interaction between cases. An ecological Bayesian model adjusted by socioeconomic factor and year was proposed to estimate the incidence by communes. Initially, there was no space-time interaction between cases, but there is evidence of clustering effect in urban areas of the region. The incidence rate for the overall study period was estimated by 6.18/100,000 (95% CI: 5.69-6.70), with a significant annual trend of 8.2% (P 1). The geographical incidence could be explained by the human development index, as a socioeconomic factor. These results suggest that children living in communes with higher socioeconomic levels may be at higher risk of developing type 1 diabetes. Our findings support the hypothesis of an aetiological role of environmental factors in the onset of type 1 diabetes.

  19. Domestication and geographic origin of Oryza sativa in China: insights from multilocus analysis of nucleotide variation of O. sativa and O. rufipogon.

    Science.gov (United States)

    Wei, Xin; Qiao, Wei-Hua; Chen, You-Tao; Wang, Rong-Sheng; Cao, Li-Rong; Zhang, Wan-Xia; Yuan, Nan-Nan; Li, Zi-Chao; Zeng, Han-Lai; Yang, Qing-Wen

    2012-10-01

    Previous studies have indicated that China is one of the domestication centres of Asian cultivated rice (Oryza sativa), and common wild rice (O. rufipogon) is the progenitor of O. sativa. However, the number of domestication times and the geographic origin of Asian cultivated rice in China are still under debate. In this study, 100 accessions of Asian cultivated rice and 111 accessions of common wild rice in China were selected to examine the relationship between O. sativa and O. rufipogon and thereby infer the domestication and evolution of O. sativa in China through sequence analyses of six gene regions, trnC-ycf6 in chloroplast genomes, cox3 in mitochondrial genomes and ITS, Ehd1, Waxy, Hd1 in nuclear genomes. The results indicated that the two subspecies of O. sativa (indica and japonica) were domesticated independently from different populations of O. rufipogon with gene flow occurring later from japonica to indica; Southern China was the genetic diversity centre of O. rufipogon, and the Pearl River basin near the Tropic of Cancer was the domestication centre of O. sativa in China.

  20. Geographical and Statistical Analysis on the Relationship between Land-Use Mixture and Home-Based Trip Making and More: Case of Richmond, Virginia

    Directory of Open Access Journals (Sweden)

    Yin - Shan MA

    2013-06-01

    Full Text Available Richmond, Virginia has implemented numerous mixed land-use policies to encourage non-private-vehicle commuting for decades based on the best practices of other cities and the assumption that land-use mixture would positively lead to trip reduction. This paper uses both Geographical Information Systems (GIS and statistical tools to empirically test this hypothesis. With local land use and trip making data as inputs, it first calculates two common indices of land-use mixture - entropy and dissimilarity indices, using GIS tool, supplemented by Microsoft Excel. Afterwards, it uses Statistical Package for Social Sciences (SPSS to calculate the correlation matrices among land-use mixture indices, socioeconomic variables, and home-based work/other trip rates, followed by a series of regression model runs on these variables. Through this study, it has been found that land-use mixture has some but weak effects on home-based work trip rate, and virtually no effects on home-based other trip rate. In contrast, socioeconomic variables, especially auto ownership, have larger effects on home-based trip making.

  1. Early childhood aggression

    OpenAIRE

    Alink, Lenneke Rosalie Agnes

    2006-01-01

    In this thesis the development, stability, and correlates of early childhood aggression were investigated. The normative development was examined in a general population sample using questionnaires completed by the parents of 12-, 24-, and 36-month-old children and again one year later. Results showed an early childhood aggression curve, with increasing rates of aggression in the second year of life and decreasing rates in the fourth year. One-year stabilities were moderate for 12-month-olds ...

  2. Nutrition in childhood

    OpenAIRE

    Bartolo, Marie Claire

    2014-01-01

    Childhood is the stage in a human’s life associated with growth and development. Growth proceeds rapidly in early life, slows down in middle childhood and accelerates at puberty before linear growth ceases. With increasing age there is also physical and psychomotor maturation, which influences activity, body composition, feeding skills and food choices (Geissler, 2011). Adequate nutrition is essential for growth, health and development of children. Poor nutrition in...

  3. Febrile Seizures: Etiology, Prevalence, and Geographical Variation

    Directory of Open Access Journals (Sweden)

    Ali DELPISHEH

    2014-07-01

    Full Text Available How to Cite This Article: Delpisheh A, Veisani Y, Sayehmiri K, Fayyazi A. Febrile Seizures: Etiology, Prevalence, and Geographical Variation. Iran J Child Neurol. 2014 Summer; 8(3:30-37. AbstractObjectiveFebrile seizures (FSs are the most common neurological disorder observed in the pediatric age group. The present study provides information about epidemiological and clinical characteristics as well as risk factors associated with FS among Iranian children.Materials & MethodsOn the computerized literature valid databases, the FS prevalence and 95% confidence intervals were calculated using a random effects model. A metaregression analysis was introduced to explore heterogeneity between studies. Data manipulation and statistical analyses were performed using Stata10.ResultsThe important viral or bacterial infection causes of FSs were; recent upper respiratory infection 42.3% (95% CI: 37.2%–47.4%, gastroenteritis21.5% (95% CI: 13.6%–29.4%, and otitis media infections15.2% (95% CI: 9.8%- 20.7% respectively. The pooled prevalence rate of FS among other childhood convulsions was 47.9% (95% CI: 38.8–59.9%. The meta–regression analysis showed that the sample size does not significantly affect heterogeneity for the factor ‘prevalence FS’.ConclusionsAlmost half of all childhood convulsions among Iranian children are associated with Febrile seizure. ReferencesFelipe L, Siqueira M. febrile seizures: update on diagnosis and management. Siqueira LFM. 2010;56 (4:489–92.Oka E, Ishida S, Ohtsuka Y, Ohtahara S. Neuroepidemiological Study of Childhood Epilepsy by Application of International Classification of Epilepsies and Epileptic Syndromes (ILAE, 1989. Epilepsia. 1995;36 (7:658–61.Shi X, Lin Z, Ye X, Hu Y, Zheng F, Hu H. An epidemiological survey of febrile convulsions among pupils in the Wenzhou region. Zhongguo Dang Dai Er Ke Za Zhi. 2012 Feb;14 (2:128–30.Waruiru C, Appleton R. Febrile seizures: an update. Arch Dis Child

  4. Associations between maternal and paternal parenting behaviors, anxiety and its precursors in early childhood: A meta-analysis

    NARCIS (Netherlands)

    E.L. Möller; M. Nikolić; M. Majdandžić; S.M. Bögels

    2016-01-01

    In this meta-analysis we investigated differential associations between maternal and paternal parenting behaviors (overcontrol, overprotection, overinvolvement, autonomy granting, challenging parenting) and anxiety and its precursors (fearful temperament, behavioral inhibition, shyness) in children

  5. Use of GIS (Geographic Information Systems) and analysis of demand: an analysis for predictions in the energy segment; O emprego do SIG (Sistema de Informacoes Geograficas) e a analise de demanda: um ensaio para previsoes no segmento de energia

    Energy Technology Data Exchange (ETDEWEB)

    Castro, Jorge Henrique de [Petroleo Brasileiro SA. (PETROBRAS), Rio de Janeiro, RJ (Brazil). Unidade de Gas e Energia

    2008-07-01

    The energy assumed a preponderant paper to the current societies because it became the number spine of both economic and social activities developed. Technological advances and the economic and social development of the nations, was based on the transformation and use of natural resources in products and services. Such transformation if gave more of accented form from the Industrial Revolution where the substitution of activities until then carried through by the man, for the job of machines, transformed the way of life and the behavior of the society. Particularly the projection of demand of energy send to the following duality: the problem should be evaluated in a wide way, in other words, considering the whole range of component variables of the decision process for generation and allocation of the energy supply; however, in a local way regarding with the search of models that optimize of the energy potentials and the consequent search of value added market. Historically the forecast of the energy demand uses the GDP mainly. It is presupposed that the association of such variables to the areas that these act, or polygons that delimit them, it happens in a homogeneous way and that the limits of such areas constitute an identified change of behavior. However, this premise is false, because such polygons are defined for operational and / or politician criteria not having warranty that such distributions are really homogeneous. As solution, the development and use of decision support systems based on GIS (Geographic Information System) technology has been along the last years a powerful modeling and simulation tool. The objective of this paper is to introduce the application of techniques of spatial analysis in the activity of projection, activity that is inherent to the forecast energy demand, to mitigate the future developments of scientific models and applications associates. (author)

  6. Ecological and Geographical Analysis of the Distribution of the Mountain Tapir (Tapirus pinchaque) in Ecuador: Importance of Protected Areas in Future Scenarios of Global Warming

    Science.gov (United States)

    Ortega-Andrade, H. Mauricio; Prieto-Torres, David A.; Gómez-Lora, Ignacio; Lizcano, Diego J.

    2015-01-01

    In Ecuador, Tapirus pinchaque is considered to be critically endangered. Although the species has been registered in several localities, its geographic distribution remains unclear, and the effects of climate change and current land uses on this species are largely unknown. We modeled the ecological niche of T. pinchaque using MaxEnt, in order to assess its potential adaptation to present and future climate change scenarios. We evaluated the effects of habitat loss due by current land use, the ecosystem availability and importance of Ecuadorian System of Protected Areas into the models. The model of environmental suitability estimated an extent of occurrence for species of 21,729 km2 in all of Ecuador, mainly occurring along the corridor of the eastern Ecuadorian Andes. A total of 10 Andean ecosystems encompassed ~98% of the area defined by the model, with herbaceous paramo, northeastern Andean montane evergreen forest and northeastern Andes upper montane evergreen forest being the most representative. When considering the effect of habitat loss, a significant reduction in model area (~17%) occurred, and the effect of climate change represented a net reduction up to 37.86%. However, the synergistic effect of both climate change and habitat loss, given current land use practices, could represent a greater risk in the short-term, leading to a net reduction of 19.90 to 44.65% in T. pinchaque’s potential distribution. Even under such a scenarios, several Protected Areas harbor a portion (~36 to 48%) of the potential distribution defined by the models. However, the central and southern populations are highly threatened by habitat loss and climate change. Based on these results and due to the restricted home range of T. pinchaque, its preference for upland forests and paramos, and its small estimated population size in the Andes, we suggest to maintaining its current status as Critically Endangered in Ecuador. PMID:25798851

  7. Ecological and geographical analysis of the distribution of the mountain tapir (Tapirus pinchaque in Ecuador: importance of protected areas in future scenarios of global warming.

    Directory of Open Access Journals (Sweden)

    H Mauricio Ortega-Andrade

    Full Text Available In Ecuador, Tapirus pinchaque is considered to be critically endangered. Although the species has been registered in several localities, its geographic distribution remains unclear, and the effects of climate change and current land uses on this species are largely unknown. We modeled the ecological niche of T. pinchaque using MaxEnt, in order to assess its potential adaptation to present and future climate change scenarios. We evaluated the effects of habitat loss due by current land use, the ecosystem availability and importance of Ecuadorian System of Protected Areas into the models. The model of environmental suitability estimated an extent of occurrence for species of 21,729 km2 in all of Ecuador, mainly occurring along the corridor of the eastern Ecuadorian Andes. A total of 10 Andean ecosystems encompassed ~98% of the area defined by the model, with herbaceous paramo, northeastern Andean montane evergreen forest and northeastern Andes upper montane evergreen forest being the most representative. When considering the effect of habitat loss, a significant reduction in model area (~17% occurred, and the effect of climate change represented a net reduction up to 37.86%. However, the synergistic effect of both climate change and habitat loss, given current land use practices, could represent a greater risk in the short-term, leading to a net reduction of 19.90 to 44.65% in T. pinchaque's potential distribution. Even under such a scenarios, several Protected Areas harbor a portion (~36 to 48% of the potential distribution defined by the models. However, the central and southern populations are highly threatened by habitat loss and climate change. Based on these results and due to the restricted home range of T. pinchaque, its preference for upland forests and paramos, and its small estimated population size in the Andes, we suggest to maintaining its current status as Critically Endangered in Ecuador.

  8. Dietary analysis of Late Cenozoic Mexican equids from three different geographic/geologic settings using stable carbon isotopes: Coincidences, differences and paleobiologic significance

    Science.gov (United States)

    Pérez-Crespo, Víctor Adrian; Ferrusquía-Villafranca, Ismael; Bravo-Cuevas, Víctor Manuel; Morales-Puente, Pedro; Ruiz-González, José E.

    2016-03-01

    The development of Vertebrate Paleontology in Mexico is uneven, so that there is a strong bias in favor of Neogene/Quaternary mammals largely collected in the Trans-Mexican Volcanic Belt (TMVB hereafter) and Central Plateau (CeP hereafter) Morphotectonic Provinces [MP hereafter]; however, the time is ripe for pursuing research in other than taxonomic areas. Here we investigate C3/C4 plant consumption in the equid lineage in three such provinces, which provide different geographic/geologic and paleoecologic scenarios during the Barstovian, Hemphillian and Rancholabrean times. Our results show that the Barstovian equids from Oaxaca, Sierra Madre del Sur MP Cormohipparion aff. C. quinni, Merychippus cf. M. sejunctus and Pliohippus sp. largely fed on C3 plants, which were the chief food stuff of horses in Mexico, particularly in the Southeast. On the other hand, the Hemphillian equid from Guanajuato, CeP Astrohippus stocki, was an unbalanced C3/C4 mixed feeders in favor of C4 plants, a fact that indicates a profound plant diversification due to the inception and rapid diversification of C4 plants that occurred there at this time, as it occurred in temperate North America, resulting in the differential consumption of C4 plants over that of C3 plants. Such trend prevailed until the Rancholabrean, as born out by the inferred diet for Equus conversidens and Equus sp. from Hidalgo, TMVB. Clearly then, the coeval diet change observed in Mexico and temperate North America implies a correlative vegetation change resulting in the appearance and rapid diversification of C4 plants, which largely formed the preferred food stuff of equids since the Hemphillian, although some C3 plant consumption was maintained till the Rancholabrean. It should be noted that the development of hypsodonty in equids and many artiodactyls, has long been interpreted as the adaptive mammalian response to the new feeding conditions.

  9. 海南西部干旱的地理边缘解析%Analysis of Drought in Western Hainan from the Perspective of Geographical Fringes

    Institute of Scientific and Technical Information of China (English)

    廖继武; 周永章

    2012-01-01

    Western Hainan is located in tropical zone, but its climate is very arid, and the drought has become a promi- nent problem in the development of local agriculture. Based on historical data of the drought, its characteristics, origin and forming mechanism have been studied in western Hainan from the perspective of geographic fringes. Drought is a 10-year cycle of undulant change, and the degree of drought reduces from coastal areas to inland. Western Hainan is the sea-content ecotone and mountain-plain ecotone, and the three systems of mountains, plains and ocean play different function in the formation of drought in western Hainan. The results provide a scientific basis for western Hainan to pre- vent and treat the drought.%地处热带的海南西部干旱问题突出,干旱已经成为当地发展农业生产的制约因素。从地理边缘视角,根据历史资料研究海南西部的干旱特征与成因,为海南西部干旱防治提供科学依据,可丰富区域干旱研究的内容与方法。研究发现,海南西部干旱具有以10年为周期的波状变化,干旱程度由沿海向内陆递减;海南西部是海陆交错带与山地平原交错带,山地、平原、海洋三大系统在干旱形成过程中发挥着不同的作用。

  10. Multi-approaches analysis reveals local adaptation in the emmer wheat (Triticum dicoccoides) at macro- but not micro-geographical scale.

    Science.gov (United States)

    Volis, Sergei; Ormanbekova, Danara; Yermekbayev, Kanat; Song, Minshu; Shulgina, Irina

    2015-01-01

    Detecting local adaptation and its spatial scale is one of the most important questions of evolutionary biology. However, recognition of the effect of local selection can be challenging when there is considerable environmental variation across the distance at the whole species range. We analyzed patterns of local adaptation in emmer wheat, Triticum dicoccoides, at two spatial scales, small (inter-population distance less than one km) and large (inter-population distance more than 50 km) using several approaches. Plants originating from four distinct habitats at two geographic scales (cold edge, arid edge and two topographically dissimilar core locations) were reciprocally transplanted and their success over time was measured as 1) lifetime fitness in a year of planting, and 2) population growth four years after planting. In addition, we analyzed molecular (SSR) and quantitative trait variation and calculated the QST/FST ratio. No home advantage was detected at the small spatial scale. At the large spatial scale, home advantage was detected for the core population and the cold edge population in the year of introduction via measuring life-time plant performance. However, superior performance of the arid edge population in its own environment was evident only after several generations via measuring experimental population growth rate through genotyping with SSRs allowing counting the number of plants and seeds per introduced genotype per site. These results highlight the importance of multi-generation surveys of population growth rate in local adaptation testing. Despite predominant self-fertilization of T. dicoccoides and the associated high degree of structuring of genetic variation, the results of the QST - FST comparison were in general agreement with the pattern of local adaptation at the two spatial scales detected by reciprocal transplanting.

  11. Ecological and geographical analysis of the distribution of the mountain tapir (Tapirus pinchaque) in Ecuador: importance of protected areas in future scenarios of global warming.

    Science.gov (United States)

    Ortega-Andrade, H Mauricio; Prieto-Torres, David A; Gómez-Lora, Ignacio; Lizcano, Diego J

    2015-01-01

    In Ecuador, Tapirus pinchaque is considered to be critically endangered. Although the species has been registered in several localities, its geographic distribution remains unclear, and the effects of climate change and current land uses on this species are largely unknown. We modeled the ecological niche of T. pinchaque using MaxEnt, in order to assess its potential adaptation to present and future climate change scenarios. We evaluated the effects of habitat loss due by current land use, the ecosystem availability and importance of Ecuadorian System of Protected Areas into the models. The model of environmental suitability estimated an extent of occurrence for species of 21,729 km2 in all of Ecuador, mainly occurring along the corridor of the eastern Ecuadorian Andes. A total of 10 Andean ecosystems encompassed ~98% of the area defined by the model, with herbaceous paramo, northeastern Andean montane evergreen forest and northeastern Andes upper montane evergreen forest being the most representative. When considering the effect of habitat loss, a significant reduction in model area (~17%) occurred, and the effect of climate change represented a net reduction up to 37.86%. However, the synergistic effect of both climate change and habitat loss, given current land use practices, could represent a greater risk in the short-term, leading to a net reduction of 19.90 to 44.65% in T. pinchaque's potential distribution. Even under such a scenarios, several Protected Areas harbor a portion (~36 to 48%) of the potential distribution defined by the models. However, the central and southern populations are highly threatened by habitat loss and climate change. Based on these results and due to the restricted home range of T. pinchaque, its preference for upland forests and paramos, and its small estimated population size in the Andes, we suggest to maintaining its current status as Critically Endangered in Ecuador.

  12. 1338例儿童情绪障碍的临床分析%The Clinical Analysis of 1338 Cases with Childhood Emotional Disorders

    Institute of Scientific and Technical Information of China (English)

    梅其霞; 王敏建; 杨世华; 魏华

    2011-01-01

    childhood emotional disorders: 36.6% anxiety disorder ( including 14.3% separation anxiety disorder), 12.4% hysteria, 12.0% depression neurosis, 11.4% obsessive compulsive neurosis, 10. 0% phobia and 17. 6% mixed type;( 5 )68. 4% emotional instability among 98 children with separation anxiety disorders by Analysis of Eysenck personality; ( 6 ) 76.1% were due to unhealthy methods of parenting among 88 children with separation anxiety disorder, such as excessive protection and excessive replacement, excessive restriction, etc. ; (7)34.3% just had single psychotherapy, 65.7 % had psychotherapy and drug treatment and all cases showed good curative effect. Conclusions: Childhood emotional disorders are more common in girls and teenagers, resulting in more anxiety disorders, due to personality tendency and unhealthy parenting methods.

  13. Infection and childhood leukemia: review of evidence

    Directory of Open Access Journals (Sweden)

    Raquel da Rocha Paiva Maia

    2013-12-01

    Full Text Available OBJECTIVE : To analyze studies that evaluated the role of infections as well as indirect measures of exposure to infection in the risk of childhood leukemia, particularly acute lymphoblastic leukemia. METHODS : A search in Medline, Lilacs, and SciELO scientific publication databases initially using the descriptors “childhood leukemia” and “infection” and later searching for the words “childhood leukemia” and “maternal infection or disease” or “breastfeeding” or “daycare attendance” or “vaccination” resulted in 62 publications that met the following inclusion criteria: subject aged ≤ 15 years; specific analysis of cases diagnosed with acute lymphoblastic leukemia or total leukemia; exposure assessment of mothers’ or infants’ to infections (or proxy of infection, and risk of leukemia. RESULTS : Overall, 23 studies that assessed infections in children support the hypothesis that occurrence of infection during early childhood reduces the risk of leukemia, but there are disagreements within and between studies. The evaluation of exposure to infection by indirect measures showed evidence of reduced risk of leukemia associated mainly with daycare attendance. More than 50.0% of the 16 studies that assessed maternal exposure to infection observed increased risk of leukemia associated with episodes of influenza, pneumonia, chickenpox, herpes zoster, lower genital tract infection, skin disease, sexually transmitted diseases, Epstein-Barr virus, and Helicobacter pylori . CONCLUSIONS : Although no specific infectious agent has been identified, scientific evidence suggests that exposure to infections has some effect on childhood leukemia etiology.

  14. Effect of iron intervention on growth during gestation, infancy, childhood, and adolescence: a systematic review with meta-analysis

    NARCIS (Netherlands)

    Vucic, V.; Berti, C.; Vollhardt, C.; Fekete, K.; Cetin, I.; Koletzko, B.; Gurinovic, M.; Veer, van 't P.

    2013-01-01

    To evaluate the effect of iron intervention on physical growth in fetuses, infants, children, and adolescents up to 18 years of age, a systematic review with meta-analysis of randomized controlled trials (RCTs) was conducted. Structured electronic searches were conducted to February 2010 using MEDLI

  15. Privatization of Early Childhood Education in Iceland

    Science.gov (United States)

    Dýrfjörð, Kristín; Magnúsdóttir, Berglind Rós

    2016-01-01

    The overall aim of this paper is to give a comprehensive picture of the marketization of early childhood education in Iceland. Our theoretical framework is based on Hursh's (2007) analysis of how the governance of schools is reshaped to serve a neoliberal agenda with the help of internal and external privatization (Ball and Youdell, 2007). In this…

  16. Childhood and Citizenship: A Conversation across Modernity

    Science.gov (United States)

    Dunne, Joseph

    2006-01-01

    This paper analyses the problematic nature of citizenship as a modern achievement faced with the challenge of vindicating ancient ideals in what is increasingly considered to be a "postmodern" world. It offers a parallel analysis of childhood as a characteristically modern construct whose reality in children's life-worlds is threatened by social…

  17. Uveitis in childhood : clinical and fundamental developments

    NARCIS (Netherlands)

    Kalinina Ayuso, V.

    2013-01-01

    This thesis aimed to gain new insights regarding the course and prognosis of uveitis in childhood, the pathogenesis of JIA-uveitis and the treatment of uveitis in children. The role of baseline prognostic factors in JIA-uveitis was studied by a retrospective analysis of 117 affected eyes of 65 patie

  18. Forest and wildlife habitat analysis using remote sensing and geographic information systems. M.S. Thesis, 26 May 1992 Abstract Only

    Science.gov (United States)

    Fiorella, Maria

    1995-01-01

    Forest and wildlife habitat analyses were conducted at the H.J. Andrews Experimental Forest in the Central Cascade Mountains of Oregon using remotely sensed data and a geographic information system (GIS). Landsat Thematic Mapper (TM) data were used to determine forest successional stages, and to analyze the structure of both old and young conifer forests. Two successional stage maps were developed. One was developed from six TM spectral bands alone, and the second was developed from six TM spectral bands and a relative sun incidence band. Including the sun incidence band in the classification improved the mapping accuracy in the two youngest successional stages, but did not improve overall accuracy or accuracy of the two oldest successional stages. Mean spectral values for old-growth and mature stands were compared in seven TM bands and seven band transformations. Differences between mature and old-growth successional stages were greatest for the band ratio of TM 4/5 (P = 0.00005) and the multiband transformation of wetness (P = 0.00003). The age of young conifer stands had the highest correlation to TM 4/5 values (r = 0.9559) of any of the TM band or band transformations used. TM 4/5 ratio values of poorly regenerated conifer stands were significantly different from well regenerated conifer stands after age 15 (P = 0.0000). TM 4/5 was named a 'Successional Stage Index' (SSI) because of its ability to distinguish forest successional stages. The forest successional stage map was used as input into a vertebrate richness model using GIS. The three variables of (1) successional stage, (2) elevation, and (3) site moisture were used in the GIS to predict the spatial occurrence of small mammal, amphibian, and reptile species based on primary and secondary habitat requirements. These occurrence or habitat maps were overlayed to tally the predicted number of vertebrate at any given point in the study area. Overall, sixty-three and sixty-seven percent of the model

  19. Geographical information system and environmental epidemiology: a cross-sectional spatial analysis of the effects of traffic-related air pollution on population respiratory health

    Science.gov (United States)

    2011-01-01

    Background Traffic-related air pollution is a potential risk factor for human respiratory health. A Geographical Information System (GIS) approach was used to examine whether distance from a main road (the Tosco-Romagnola road) affected respiratory health status. Methods We used data collected during an epidemiological survey performed in the Pisa-Cascina area (central Italy) in the period 1991-93. A total of 2841 subjects participated in the survey and filled out a standardized questionnaire on health status, socio-demographic information, and personal habits. A variable proportion of subjects performed lung function and allergy tests. Highly exposed subjects were defined as those living within 100 m of the main road, moderately exposed as those living between 100 and 250 m from the road, and unexposed as those living between 250 and 800 m from the road. Statistical analyses were conducted to compare the risks for respiratory symptoms and diseases between exposed and unexposed. All analyses were stratified by gender. Results The study comprised 2062 subjects: mean age was 45.9 years for men and 48.9 years for women. Compared to subjects living between 250 m and 800 m from the main road, subjects living within 100 m of the main road had increased adjusted risks for persistent wheeze (OR = 1.76, 95% CI = 1.08-2.87), COPD diagnosis (OR = 1.80, 95% CI = 1.03-3.08), and reduced FEV1/FVC ratio (OR = 2.07, 95% CI = 1.11-3.87) among males, and for dyspnea (OR = 1.61, 95% CI = 1.13-2.27), positivity to skin prick test (OR = 1.83, 95% CI = 1.11-3.00), asthma diagnosis (OR = 1.68, 95% CI = 0.97-2.88) and attacks of shortness of breath with wheeze (OR = 1.67, 95% CI = 0.98-2.84) among females. Conclusion This study points out the potential effects of traffic-related air pollution on respiratory health status, including lung function impairment. It also highlights the added value of GIS in environmental health research. PMID:21362158

  20. CHEMICAL PROFILES OF HONEYS ORIGINATING FROM DIFFERENT FLORAL SOURCES AND GEOGRAPHIC LOCATIONS EXAMINED BY A COMBINATION OF THREE EXTRACTION AND ANALYSIS TECHNIQUES

    Directory of Open Access Journals (Sweden)

    D. M. Meloncelli

    2015-05-01

    Full Text Available The chemical profiles of Tasmanian Leatherwood and Manuka honeys from Tasmania and New Zealand have been compared by a combination of GC-MS analysis of volatiles and semi-volatiles, RP-HPLC-DAD analysis of phenolics and flavonoids and HPLC-DAD analysis of derivatised dihydroxyacetone, hydroxymethylfurfural and methylglyoxal. This study found that Tasmanian and New Zealand Manuka honeys have high concentrations of methylglyoxal. However, syringic acid was only detected in Manuka honeys grown in New Zealand. The Tasmanian honeys can be distinguished by the higher concentration of 3-phenyllactic acid in Manuka compared to Leatherwood floral sources.

  1. CHEMICAL PROFILES OF HONEYS ORIGINATING FROM DIFFERENT FLORAL SOURCES AND GEOGRAPHIC LOCATIONS EXAMINED BY A COMBINATION OF THREE EXTRACTION AND ANALYSIS TECHNIQUES

    Directory of Open Access Journals (Sweden)

    D. M. Meloncelli,

    2015-02-01

    Full Text Available The chemical profiles of Tasmanian Leatherwood and Manuka honeys from Tasmania and New Zealand have been compared by a combination of GC-MS analysis of volatiles and semi-volatiles, RP-HPLC-DAD analysis of phenolics and flavonoids and HPLC-DAD analysis of derivatised dihydroxyacetone, hydroxymethylfurfural and methylglyoxal. This study found that Tasmanian and New Zealand Manuka honeys have high concentrations of methylglyoxal. However, syringic acid was only detected in Manuka honeys grown in New Zealand. The Tasmanian honeys can be distinguished by the higher concentration of 3-phenyllactic acid in Manuka compared to Leatherwood floral sources.

  2. A Geographical Heuristic Routing Protocol for VANETs

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    Luis Urquiza-Aguiar

    2016-09-01

    Full Text Available Vehicular ad hoc networks (VANETs leverage the communication system of Intelligent Transportation Systems (ITS. Recently, Delay-Tolerant Network (DTN routing protocols have increased their popularity among the research community for being used in non-safety VANET applications and services like traffic reporting. Vehicular DTN protocols use geographical and local information to make forwarding decisions. However, current proposals only consider the selection of the best candidate based on a local-search. In this paper, we propose a generic Geographical Heuristic Routing (GHR protocol that can be applied to any DTN geographical routing protocol that makes forwarding decisions hop by hop. GHR includes in its operation adaptations simulated annealing and Tabu-search meta-heuristics, which have largely been used to improve local-search results in discrete optimization. We include a complete performance evaluation of GHR in a multi-hop VANET simulation scenario for a reporting service. Our study analyzes all of the meaningful configurations of GHR and offers a statistical analysis of our findings by means of MANOVA tests. Our results indicate that the use of a Tabu list contributes to improving the packet delivery ratio by around 5% to 10%. Moreover, if Tabu is used, then the simulated annealing routing strategy gets a better performance than the selection of the best node used with carry and forwarding (default operation.

  3. HIV care for geographically mobile populations.

    Science.gov (United States)

    Taylor, Barbara S; Garduño, L Sergio; Reyes, Emily V; Valiño, Raziel; Rojas, Rita; Donastorg, Yeycy; Brudney, Karen; Hirsch, Jennifer

    2011-01-01

    The interaction between geographic mobility and risk for human immunodeficiency virus infection is well recognized, but what happens to those same individuals, once infected, as they transition to living with the infection? Does mobility affect their transition into medical care? If so, do mobile and nonmobile populations achieve similar success with antiretroviral treatment? The definition of mobility has changed over the centuries to encompass a complex phenotype including permanent migration, frequent travel, circular migration, and travel to and from treatment centers. The heterogeneity of these definitions leads to discordant findings. Investigations show that mobility has an impact on infection risk, but fewer data exist on the impact of geographic mobility on medical care and treatment outcomes. This review will examine existing data regarding the impact of geographic mobility on access to and maintenance in medical care and on adherence to antiretroviral therapy for those living with human immunodeficiency virus infection. It will also expand the concept of mobility to include data on the impact of the distance from residence to clinic on medical care and treatment adherence. Our conclusions are that the existing literature is limited by varying definitions of mobility and the inherent oversimplification necessary to apply a "mobility measure" in a statistical analysis. The impact of mobility on antiretroviral treatment outcomes deserves further exploration to both define the phenomenon and target interventions to these at-risk populations.

  4. Serum metabolomics study and eicosanoid analysis of childhood atopic dermatitis based on liquid chromatography-mass spectrometry.

    Science.gov (United States)

    Huang, Yan; Chen, Guoyou; Liu, Xinyu; Shao, Yaping; Gao, Peng; Xin, Chenchen; Cui, Zhenze; Zhao, Xinjie; Xu, Guowang

    2014-12-05

    Atopic dermatitis (AD) is the most common inflammatory skin disease in children. In the study, ultra high performance liquid chromatography-mass spectrometry was used to investigate serum metabolic abnormalities of AD children. Two batch fasting sera were collected from AD children and healthy control; one of them was for nontargeted metabolomics analysis, the other for targeted eicosanoids analysis. AD children were divided into high immunoglobulin E (IgE) group and normal IgE group. On the basis of the two analysis approaches, it was found that the differential metabolites of AD, leukotriene B4, prostaglandins, conjugated bile acids, etc., were associated with inflammatory response and bile acids metabolism. Carnitines, free fatty acids, lactic acid, etc., increased in the AD group with high IgE, which revealed energy metabolism disorder. Amino acid metabolic abnormalities and increased levels of Cytochrome P450 epoxygenase metabolites were found in the AD group with normal IgE. The results provided a new perspective to understand the mechanism and find potential biomarkers of AD and may provide a new reference for personalized treatment.

  5. Conditional Survival in Pediatric Malignancies: Analysis of data from the Childhood Cancer Survivor Study and the Surveillance, Epidemiology and End Results Program

    Science.gov (United States)

    Mertens, Ann C; Yong, Jian; Dietz, Andrew; Kreiter, Erin; Yasui, Yutaka; Bleyer, Archie; Armstrong, Gregory T; Robison, Leslie L; Wasilewski-Masker, Karen

    2015-01-01

    Background Long-term survivors of pediatric cancer are at risk for life-threatening late effects of their cancer. Previous studies have shown excesses in long-term mortality within high-risk groups defined by demographic and treatment characteristics. Methods To investigate conditional survival in a pediatric cancer population, we performed an analysis of conditional survival in the original Childhood Cancer Survivor Study (CCSS) cohort and the Surveillance, Epidemiology and End Results (SEER) database registry. The overall probability of death for patients in 5 years and 10 years after they survived 5, 10, 15, and 20 years since cancer diagnosis, and cause-specific death in 10 years for 5-year survivors were estimated using the cumulative incidence method. Results Among CCSS and SEER patients who were alive 5 years post cancer diagnosis, within each diagnosis group at least 92% are alive in the subsequent 5 years, except leukemia patients of whom only 88% of 5-year survivors remain alive in the subsequent 5 years. The probability of all-cause mortality in the next 10 years on patients who survived at least 5 years after diagnosis, was 8.8% in CCSS and 10.6% in SEER, approximately three quarter of which were due to neoplasms as causes of death. Conclusion The risk of death of pediatric cancer survivors in 10 years can vary between diagnosis groups by at most 12% even up to 20 years post diagnosis. This information is clinically important in counseling patients on their conditional survival, particularly when survivors are seen in long-term follow-up. PMID:25557134

  6. Kornati Islands on Old Geographic Maps and Charts

    OpenAIRE

    Josip Faričić; Zdenko Simičić

    2005-01-01

    Based on the analysis of cartographic sources, the paper analyses the historical and geographical development of the Kornati islands, the largest group of Croatian islands. The old maps were used first of all as the means of geographic research that, being necessarily correlated to the simultaneous historical written sources and modern topographic and maritime maps, make the basis for creating a research platform for relevant scientific results to be achieved. On the basis of the old maps it ...

  7. Changes at the National Geographic Society

    Science.gov (United States)

    Schwille, Kathleen

    2016-01-01

    For more than 125 years, National Geographic has explored the planet, unlocking its secrets and sharing them with the world. For almost thirty of those years, National Geographic has been committed to K-12 educators and geographic education through its Network of Alliances. As National Geographic begins a new chapter, they remain committed to the…

  8. Acquired childhood dysarthria: review of its clinical presentation.

    Science.gov (United States)

    van Mourik, M; Catsman-Berrevoets, C E; Paquier, P F; Yousef-Bak, E; van Dongen, H R

    1997-11-01

    The adult classification of dysarthria correlating with the pathophysiology of the motor systems is usually applied to classify acquired childhood dysarthria. However, the validity of this adult model for children has not been studied systematically. All studies pertaining to analysis of speech features in acquired childhood dysarthria published since 1980 were reviewed. Studies were classified on the basis of neuroradiologic evidence of lesion site and associated motor disorder. This review demonstrates that knowledge of acquired childhood dysarthria is based on a limited number of single case studies, most of which pertain to dysarthria occurring after resection of cerebellar tumor. Definite similarities to adult dysarthria were not evident. Some similarity to acquired childhood dysarthria due to basal ganglia lesions was detected. We conclude that acquired childhood dysarthria requires its own classification.

  9. Estimating the accuracy of geographical imputation

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    Boscoe Francis P

    2008-01-01

    Full Text Available Abstract Background To reduce the number of non-geocoded cases researchers and organizations sometimes include cases geocoded to postal code centroids along with cases geocoded with the greater precision of a full street address. Some analysts then use the postal code to assign information to the cases from finer-level geographies such as a census tract. Assignment is commonly completed using either a postal centroid or by a geographical imputation method which assigns a location by using both the demographic characteristics of the case and the population characteristics of the postal delivery area. To date no systematic evaluation of geographical imputation methods ("geo-imputation" has been completed. The objective of this study was to determine the accuracy of census tract assignment using geo-imputation. Methods Using a large dataset of breast, prostate and colorectal cancer cases reported to the New Jersey Cancer Registry, we determined how often cases were assigned to the correct census tract using alternate strategies of demographic based geo-imputation, and using assignments obtained from postal code centroids. Assignment accuracy was measured by comparing the tract assigned with the tract originally identified from the full street address. Results Assigning cases to census tracts using the race/ethnicity population distribution within a postal code resulted in more correctly assigned cases than when using postal code centroids. The addition of age characteristics increased the match rates even further. Match rates were highly dependent on both the geographic distribution of race/ethnicity groups and population density. Conclusion Geo-imputation appears to offer some advantages and no serious drawbacks as compared with the alternative of assigning cases to census tracts based on postal code centroids. For a specific analysis, researchers will still need to consider the potential impact of geocoding quality on their results and evaluate

  10. 延迟制造下供应商毗邻于制造商现象分析%Phenomenon Analysis about Suppliers' Geographical Proximity to Manufacturer under Postponed Manufacturing

    Institute of Scientific and Technical Information of China (English)

    熊恒庆

    2014-01-01

    There was little literature to analyze the phenomenon about suppliers' geographical proximity under postponed manufacturing in the existing postponement research. The phenomenon about geographical proximity was determined by the postponed manufacturing strategy implemented by the dominant manufacturers. Due to the manufacturer's ascendancy. He can prompt the other members of the supply chain to make adjustments to adapt to his Postponed manufacturing strategy. While suppliers' geographic location adjacent to the manufacturer is a reasonable solution that can relieve the contradiction between the manufacturer's product customization and his operation performance , it can reduce the negative impact of the product customization on the manufacturer's operation. Geographical proximity was conducive to the quick and reliable supply of raw materials and spare parts, to the knowledge sharing between enterprises and their close communication, to the further deepening relationship between enterprises, to the non-core business outsourcing of manufacturers. Toyota and Dell's postponement practice provided an example for the analysis of geographical proximity , and some reference to manufacturers' practice of the postponed manufacturing.%现有的延迟研究文献对延迟制造下供应商毗邻于制造商这种现象进行分析的很少。这种地理毗邻现象是由处于支配地位的制造商实施延迟制造策略所决定的。由于制造商的支配地位,能够促使其他供应链成员做出调整以适应延迟制造策略,而供应商地理位置毗邻于制造商是缓解产品定制化和运营绩效矛盾的一个合理方案,可以减少产品定制对制造商运营的不利影响。地理毗邻有利于原料及零部件快速可靠的供应;有利于企业间知识的共享和双方紧密的学习交流;有利于企业间关系的进一步深化;有利于制造商非核心业务的外包。丰田公司和戴尔公司延迟制造的实践

  11. Laps(epõlv 19. sajandi teise poole Eestis omaelulooliste tekstide näitel. Child(hood in 19th Century Estonia: a Study of Autobiographical Texts

    Directory of Open Access Journals (Sweden)

    Ave Mattheus

    2012-04-01

    using literary terminology. Although all the late 19th century Estonian childhood stories share similar techniques (such as the perspective of the first-person or personal narrative, the split of the storyteller into the first-person child and the first-person adult, story elements (such as the first memory of a room flooded by golden sunlight, and recurrent motifs (such as child’s loneliness and close relation to nature, educational strivings, each story is written in a different way. The works written by professional writers are characterised by lively dialogue, individualised descriptions of the scenery, symbols, metaphors and other stylistic devices, whereas the texts written by the so-called ordinary intellectuals are not as rich in imagery and style. It is quite natural that the childhood memories written by professional writers have better withstood the test of time. The present study is the first to have a more comprehensive view of childhood as reflected in autobiographical writing in Estonia in the 19th century and therefore is somewhat fragmented; I attempt to make a list of possible research ideas and offer some methods for analysis that may be productive in the future. The broadening of the research perspective in the temporary, linguistic and spatial sense may offer more scope; a large number of childhood stories have been published in the 20th and the 21st century in Estonia and the comparison of stories telling us about Estonian children’s childhoods with those recounting German or Russian children’s experiences may offer new insights, as these ethnic groups have occupied one and the same geographical space, although there are significant differences. Another topic for research would be the study of autobiographical texts against the background of the authors’ fictional works.

  12. Short Sleep Duration and Childhood Obesity: Cross-Sectional Analysis in Peru and Patterns in Four Developing Countries

    OpenAIRE

    Carrillo-Larco, Rodrigo M.; Antonio Bernabé-Ortiz; J. Jaime Miranda

    2014-01-01

    BACKGROUND: We aimed to describe the patterns of nutritional status and sleep duration in children from Ethiopia, India, Peru and Vietnam; to assess the association between short sleep duration and overweight and obesity, and if this was similar among boys and girls in Peru. METHODS AND FINDINGS: Analysis of the Young Lives Study, younger cohort, third round. In Ethiopia there were 1,999 observations, 2,011, 2,052 and 2,000 in India, Peru and Vietnam, respectively. Analyses included participa...

  13. Childhood trauma in bipolar disorder

    OpenAIRE

    Watson, Stuart; Gallagher, Peter; Dougall, Dominic; Porter, Richard; Moncrieff, Joanna; Ferrier, I Nicol; Young, Allan H.

    2014-01-01

    Objective: There has been little investigation of early trauma in bipolar disorder despite evidence that stress impacts on the course of this illness. We aimed to compare the rates of childhood trauma in adults with bipolar disorder to a healthy control group, and to investigate the impact of childhood trauma on the clinical course of bipolar disorder. Methods: Retrospective assessment of childhood trauma was conducted using the Childhood Trauma Questionnaire (CTQ) in 60 outpatients with bipo...

  14. Childhood trauma in bipolar disorder.

    OpenAIRE

    Watson, S; Gallagher, P.; Dougall, D.; Porter, R.; Moncrieff, J; Ferrier, I N; Young, A.H.

    2014-01-01

    Objective:There has been little investigation of early trauma in bipolar disorder despite evidence that stress impacts on the course of this illness. We aimed to compare the rates of childhood trauma in adults with bipolar disorder to a healthy control group, and to investigate the impact of childhood trauma on the clinical course of bipolar disorder.Methods:Retrospective assessment of childhood trauma was conducted using the Childhood Trauma Questionnaire (CTQ) in 60 outpatients with bipolar...

  15. Geographic latitude and prevalence of adolescent idiopathic scoliosis.

    Science.gov (United States)

    Grivas, Theodoros B; Vasiliadis, Elias; Savvidou, Olga; Mouzakis, Vasilios; Koufopoulos, Georgios

    2006-01-01

    Adolescent Idiopathic Scoliosis (AIS) prevalence has been reported to be different in various geographic latitudes and demonstrates higher values in northern countries. A study on epidemiological reports from the literature was conducted to record the prevalence of AIS among the general population of boys and girls, aged 10-16 years old, in different geographic latitudes, in order to test the hypothesis that the prevalence of AIS among boys and girls is different in various geographic latitudes and to examine if there is a possible association between them. Seventeen peer-reviewed published papers reporting AIS prevalence in the general population of boys and girls from most geographic areas of the northern hemisphere were retrieved from the literature. The geographic latitude of each centre where a particular study was originated was documented. The statistical analysis included a linear regression forward modeling procedure of the AIS prevalence by latitude, weighted by sample size. According to the modelling of the data, a significant positive association between prevalence of AIS and latitude was found for girls (p<0.001), following a rather curvilinear trend, but not a significant positive association was found for boys (p<0.111). A positive association between prevalence of AIS and geographic latitude is reported only for girls in the present study. Prevalence of AIS in boys is not associated significantly with geographic latitude. This differing significant association implicates the possible role of environmental factors in the pathogenesis of AIS that may act in a different way between boys and girls.

  16. Territorial Decentration and Geographic Learning.

    Science.gov (United States)

    Stoltman, Joseph P.

    Territorial decentration is a question of major significance to geographic educators. This paper reports the findings of a research project designed to determine the territorial decentration of an American sample of children. The primary purpose of the research was to determine if Piaget's territorial decentration stages are appropriate for…

  17. Geographic Projection of Cluster Composites

    NARCIS (Netherlands)

    Nerbonne, J.; Bosveld-de Smet, L.M.; Kleiweg, P.; Blackwell, A.; Marriott, K.; Shimojima, A.

    2004-01-01

    A composite cluster map displays a fuzzy categorisation of geographic areas. It combines information from several sources to provide a visualisation of the significance of cluster borders. The basic technique renders the chance that two neighbouring locations are members of different clusters as the

  18. Geographical Concepts in Turkish Lullabys

    Science.gov (United States)

    Çifçi, Taner

    2016-01-01

    In this study, a collection of lullabies which have an important place in Turkish culture and which form an important genre in folk literature are examined to find out distribution and presentation of geographical terms in the lullabies in this collection. In the study, 2480 lullabies in Turkish Lullabies which is one of the leading collections in…

  19. The Andes: A Geographical Portrait

    Directory of Open Access Journals (Sweden)

    Anthony Bebbington

    2016-05-01

    Full Text Available Reviewed: The Andes: A Geographical Portrait. By Axel Borsdorf and Christoph Stadel. Translated by Brigitte Scott and Christoph Stadel. Cham, Switzerland: Springer International Publishing, 2015. xiv + 368 pp. US$ 139.00. Also available as an e-book. ISBN 978-3-319-03529-1.

  20. Protection of Geographical Indication Intellectual Property of Tea in Zhejiang Province

    Institute of Scientific and Technical Information of China (English)

    Zhiguo; SUN; Wanzhen; XIONG; Shuting; WANG; Xuebin; ZHONG

    2013-01-01

    As to tea resources in Zhejiang Province at present, there are 8 kinds of national geographical indication products, 23 national geographical indication trademarks, and 7 kinds of national geographical indication of agricultural products. From the geographical indication protection, geographical indication trademark registration, geographical indication registration of agricultural products, we conduct a analysis on the current protection of geographical indication intellectual property of tea in Zhejiang Province, and put forth the following countermeasures: (i) Based on the relevant tangible cultural heritage and natural heritage, conducting in-depth study on the characteristics of natural factors and human factors concerning geographical indication of famous tea; (ii) Based on the protection pattern of national geographical indication products, registering the national geographical indication trademarks, and registering the national agricultural product geographical indication; (iii) Taking full advantage of special mark of geographical indication products and agricultural brand heritage, and integrating the tea brands within the scope of protection of geographical indication; (iv) Exploiting and arranging the intangible cultural heritage related to tea, strengthening the intangible cultural heritage protection of tea in the province, and endeavoring to include Longjing tea in the world’s intangible cultural heritage list on traditional craftsmanship of green tea.