WorldWideScience

Sample records for chemical defense program

  1. DHS Office of Health Affairs Chemical Defense Program Analyzes Subway Safety Against Chemical Terrorist Threats

    OpenAIRE

    Center for Homeland Defense and Security

    2012-01-01

    Center for Homeland Defense and Security, OUT OF THE CLASSROOM In an article for the journal Domestic Preparedness, Joselito Ignacio examines how to protect subway riders from chemical attacks. Ignacio graduated from the Center for Homeland Defense and Security in...

  2. DEFENSE PROGRAMS RISK MANAGEMENT FRAMEWORK

    Directory of Open Access Journals (Sweden)

    Constantin PREDA

    2012-01-01

    Full Text Available For the past years defense programs have faced delays in delivering defense capabilities and budget overruns. Stakeholders are looking for ways to improve program management and the decision making process given the very fluid and uncertain economic and political environment. Consequently, they have increasingly resorted to risk management as the main management tool for achieving defense programs objectives and for delivering the defense capabilities strongly needed for the soldiers on the ground on time and within limited defense budgets. Following a risk management based decision-making approach the stakeholders are expected not only to protect program objectives against a wide range of risks but, at the same time, to take advantage of the opportunities to increase the likelihood of program success. The prerequisite for making risk management the main tool for achieving defense programs objectives is the design and implementation of a strong risk management framework as a foundation providing an efficient and effective application of the best risk management practices. The aim of this paper is to examine the risk management framework for defense programs based on the ISO 31000:2009 standard, best risk management practices and the defense programs’ needs and particularities. For the purposes of this article, the term of defense programs refers to joint defense programs.

  3. The journal of medical chemical, biological and radiological defense, an update

    International Nuclear Information System (INIS)

    Price, B. B. S.; Peitersen, L.E.

    2009-01-01

    The Journal of Medical Chemical, Biological, and Radiological Defense (www.JMedCBR.org) is a peer-reviewed scientific online journal focusing on the biology, chemistry, physiology, toxicology and treatment of exposure to threat agents. JMedCBR provides a central international forum for the publication of current research and development information on medical chemical, biological and radiological defense, as well as training, doctrine, and problems related to chemical, biological and radiological casualties. JMedCBR is sponsored by the US Defense Threat Reduction Agency (DTRA) Chem-Bio Technologies Directorate as part of its scientific outreach program in chemical and biological defense solutions for the Department of Defense. In addition to scientific and medical research, JMedCBR hosts an archive of related papers from authors in the field. Although organized into annual issues, articles are published on the web continuously. The complete JMedCBR is published electronically and is made available to the scientific community free of charge. JMedCBR is committed to providing its readers with quality scientific information and critical analyses. All submissions are peer-reviewed by an editorial board of recognized and respected international scientists who represent expertise in different aspects of medical chemical, biological and radiological defense. Contributions to JMedCBR must be original works of the author(s) and must not have been previously published or simultaneously submitted to other publications. The author(s) transfer the copyright of articles published in JMedCBR to the journal. A copyright transfer form must accompany each manuscript submission. For more information on submitting to JMedCBR, see the Authors' Guide, available at http://www.jmedcbr.org/authorGuide.html.(author)

  4. Chemical defense of early life stages of benthic marine invertebrates.

    Science.gov (United States)

    Lindquist, Niels

    2002-10-01

    Accurate knowledge of factors affecting the survival of early life stages of marine invertebrates is critically important for understanding their population dynamics and the evolution of their diverse reproductive and life-history characteristics. Chemical defense is an important determinant of survival for adult stages of many sessile benthic invertebrates, yet relatively little consideration has been given to chemical defenses at the early life stages. This review examines the taxonomic breadth of early life-stage chemical defense in relation to various life-history and reproductive characteristics, as well as possible constraints on the expression of chemical defense at certain life stages. Data on the localization of defensive secondary metabolites in larvae and the fitness-related consequences of consuming even a small amount of toxic secondary metabolites underpin proposals regarding the potential for Müllerian and Batesian mimicry to occur among marine larvae. The involvement of microbial symbionts in the chemical defense of early life stages illustrates its complexity for some species. As our knowledge of chemical defenses in early life stages grows, we will be able to more rigorously examine connections among phylogeny, chemical defenses, and the evolution of reproductive and life-history characteristics among marine invertebrates.

  5. Marine biofilm bacteria evade eukaryotic predation by targeted chemical defense.

    Directory of Open Access Journals (Sweden)

    Carsten Matz

    Full Text Available Many plants and animals are defended from predation or herbivory by inhibitory secondary metabolites, which in the marine environment are very common among sessile organisms. Among bacteria, where there is the greatest metabolic potential, little is known about chemical defenses against bacterivorous consumers. An emerging hypothesis is that sessile bacterial communities organized as biofilms serve as bacterial refuge from predation. By testing growth and survival of two common bacterivorous nanoflagellates, we find evidence that chemically mediated resistance against protozoan predators is common among biofilm populations in a diverse set of marine bacteria. Using bioassay-guided chemical and genetic analysis, we identified one of the most effective antiprotozoal compounds as violacein, an alkaloid that we demonstrate is produced predominately within biofilm cells. Nanomolar concentrations of violacein inhibit protozoan feeding by inducing a conserved eukaryotic cell death program. Such biofilm-specific chemical defenses could contribute to the successful persistence of biofilm bacteria in various environments and provide the ecological and evolutionary context for a number of eukaryote-targeting bacterial metabolites.

  6. Physics of a ballistic missile defense - The chemical laser boost-phase defense

    Science.gov (United States)

    Grabbe, Crockett L.

    1988-01-01

    The basic physics involved in proposals to use a chemical laser based on satellites for a boost-phase defense are investigated. After a brief consideration of simple physical conditions for the defense, a calculation of an equation for the number of satellites needed for the defense is made along with some typical values of this for possible future conditions for the defense. Basic energy and power requirements for the defense are determined. A sumary is made of probable minimum conditions that must be achieved for laser power, targeting accuracy, number of satellites, and total sources for power needed.

  7. Defense Treaty Inspection Readiness Program

    International Nuclear Information System (INIS)

    Cronin, J.J.; Kohen, M.D.; Rivers, J.D.

    1996-01-01

    The Defense Treaty Inspection Readiness Program (DTIRP) was established by the Department of Defense in 1990 to assist defense facilities in preparing for treaty verification activities. Led by the On-Site Inspection Agency (OSIA), an element of the Department of Defense, DTIRP''s membership includes representatives from other Department of Defense agencies, the Department of Energy (DOE), the Central Intelligence Agency, the Federal Bureau of Investigation, the Department of Commerce, and others. The Office of Safeguards and Security has a significant interest in this program, due to the number of national defense facilities within its purview that are candidates for future inspections. As a result, the Office of Safeguards and Security has taken a very active role in DTIRP. This paper discusses the Office of Safeguards and Security''s increasing involvement in various elements of the DTIRP, ranging from facility assessments to training development and implementation

  8. Journal of Medical Chemical, Biological and Radiological Defense

    International Nuclear Information System (INIS)

    Price, B.

    2007-01-01

    The Journal of Medical Chemical, Biological, and Radiological Defense is a free, on-line journal dedicated to providing an international, peer-reviewed journal of original scientific research and clinical and doctrinal knowledge in the area of medical treatment and countermeasures for chemical, biological and radiological defense; and to developing and maintaining an archive of current research and development information on training, doctrine, and professional discussions of problems related to chemical, biological and radiological casualties. The Journal, www.JMedCBR.org, now in its fifth year, is sponsored by the US Defense Threat Reduction Agency. Areas of interest include, but are not limited to: Neuroprotectants; Bioscavengers for Nerve Agents; Medical Diagnostic Systems and Technologies; Medical Effects of Low Level Exposures; Toxicology and Biological Effects of TICs and TIMs; Broad Spectrum Medical Countermeasures; Treatments and Therapeutics for Bacterial, Viral and Toxin Agents; Radiological Medical Countermeasures; Clinical Treatment of Chemical, Biological or Radiological Casualties; Toxins Structures and Treatments. The Journal is supported by an editorial advisory board of distinguished scientists and researchers in the fields of CBR defense and medical treatment and countermeasures in eleven countries.(author)

  9. CHEMICAL AND BIOLOGICAL DEFENSE: Program Planning and Evaluation Should Follow Results Act Framework

    National Research Council Canada - National Science Library

    1999-01-01

    As you requested, we examined the extent to which DOD has applied the Results Act's outcome-oriented principles to the CB Defense Program, focusing in particular on research, development, testing, and evaluation (RDT&E...

  10. Review of defense display research programs

    Science.gov (United States)

    Tulis, Robert W.; Hopper, Darrel G.; Morton, David C.; Shashidhar, Ranganathan

    2001-09-01

    Display research has comprised a substantial portion of the defense investment in new technology for national security for the past 13 years. These investments have been made by the separate service departments and, especially, via several Defense Research Projects Agency (DARPA) programs, known collectively as the High Definition Systems (HDS) Program (which ended in 2001) and via the Office of the Secretary of Defense (OSD) Defense Production Act (DPA) Title III Program (efforts ended in 2000). Using input from the Army, Navy, and Air Force to focus research and identify insertion opportunities, DARPA and the Title III Program Office have made investments to develop the national technology base and manufacturing infrastructure necessary to meet the twin challenge of providing affordable displays in current systems and enabling the DoD strategy of winning future conflicts by getting more information to all participants during the battle. These completed DARPA and DPA research and infrastructure programs are reviewed. Service investments have been and are being made to transition display technology; examples are described. Display science and technology (S&T) visions are documented for each service to assist the identification of areas meriting consideration for future defense research.

  11. Defense Transuranic Waste Program Strategy Document

    International Nuclear Information System (INIS)

    1984-01-01

    The Defense Transuranic Waste Program (DTWP) Strategy Document presents the general strategy for managing transuranic (TRU) waste materials generated during defense and research activities regulated by the US Department of Energy. The Strategy Document includes discussion of objectives and activities relating to the entire Defense Transuranic Waste Program. However, the primary focus is on the specific management responsibilities of the Transuranic Waste Lead Organization (TLO). The document also includes an updated summary of progress on TLO-managed activities over the past year

  12. Recycling and surplus chemical programs

    International Nuclear Information System (INIS)

    Harper, T.J.

    1993-05-01

    In 1988, 45 years of defense production came to a close at the US Department of Energy (DOE) Hanford Site. The mission of the Hanford Site was formally changed to environmental restoration and remediation. Westinghouse Hanford Company (WHC) is the management and operations (M ampersand O) contractor leading the cleanup. Within the framework of future Site cleanup, Hanford recycling and surplus chemical programs are making a viable contribution today to waste minimization, diversion of materials from the waste stream, and setting a standard for future operations. This paper focuses on two successful efforts: paper recycling and surplus chemical sales

  13. FY85 Program plan for the Defense Transuranic Waste Program (DTWP)

    International Nuclear Information System (INIS)

    1984-11-01

    The Defense TRU Waste Program (DTWP) is the focal point for the Department of Energy in national planning, integration, and technical development for TRU waste management. The scope of this program extends from the point of TRU waste generation through delivery to a permanent repository. The TRU program maintains a close interface with repository development to ensure program compatibility and coordination. The defense TRU program does not directly address commercial activities that generate TRU waste. Instead, it is concerned with providing alternatives to manage existing and future defense TRU wastes. The FY85 Program Plan is consistent with the Defense TRU Waste Program goals and objectives stated in the Defense Transuranic Waste Program Strategy Document, January 1984. The roles of participants, the responsibilities and authorities for Research and Development (R and D), the organizational interfaces and communication channels for R and D and the establishment of procedures for planning, reporting, and budgeting of all R and D activities meet requirements stated in the Technical Management Plan for the Transuranic Waste Management Program. The Program Plan is revised as needed. The work breakdown structure is reflected graphically immediately following the Administration section and is described in the subsequent narrative. Detailed budget planning (i.e., programmatic funding and capital equipment) is presented for FY85; outyear budget projections are presented for future years

  14. Chemical and biological nonproliferation program. FY99 annual report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This document is the first of what will become an annual report documenting the progress made by the Chemical and Biological Nonproliferation Program (CBNP). It is intended to be a summary of the program's activities that will be of interest to both policy and technical audiences. This report and the annual CBNP Summer Review Meeting are important vehicles for communication with the broader chemical and biological defense and nonproliferation communities. The Chemical and Biological Nonproliferation Program Strategic Plan is also available and provides additional detail on the program's context and goals. The body of the report consists of an overview of the program's philosophy, goals and recent progress in the major program areas. In addition, an appendix is provided with more detailed project summaries that will be of interest to the technical community.

  15. Chemical and biological nonproliferation program. FY99 annual report; ANNUAL

    International Nuclear Information System (INIS)

    NONE

    2000-01-01

    This document is the first of what will become an annual report documenting the progress made by the Chemical and Biological Nonproliferation Program (CBNP). It is intended to be a summary of the program's activities that will be of interest to both policy and technical audiences. This report and the annual CBNP Summer Review Meeting are important vehicles for communication with the broader chemical and biological defense and nonproliferation communities. The Chemical and Biological Nonproliferation Program Strategic Plan is also available and provides additional detail on the program's context and goals. The body of the report consists of an overview of the program's philosophy, goals and recent progress in the major program areas. In addition, an appendix is provided with more detailed project summaries that will be of interest to the technical community

  16. Future directions of defense programs high-level waste technology programs

    International Nuclear Information System (INIS)

    Chee, T.C.; Shupe, M.W.; Turner, D.A.; Campbell, M.H.

    1987-01-01

    The Department of Energy has been managing high-level waste from the production of nuclear materials for defense activities over the last forty years. An objective for the Defense Waste and Transportation Management program is to develop technology which ensures the safe, permanent disposal of all defense radioactive wastes. Technology programs are underway to address the long-term strategy for permanent disposal of high-level waste generated at each Department of Energy site. Technology is being developed for assessing the hazards, environmental impacts, and costs of each long-term disposal alternative for selection and implementation. This paper addresses key technology development areas, and consideration of recent regulatory requirements associated with the long-term management of defense radioactive high-level waste

  17. Egg Production Constrains Chemical Defenses in a Neotropical Arachnid.

    Directory of Open Access Journals (Sweden)

    Taís M Nazareth

    Full Text Available Female investment in large eggs increases the demand for fatty acids, which are allocated for yolk production. Since the biosynthetic pathway leading to fatty acids uses the same precursors used in the formation of polyketides, allocation trade-offs are expected to emerge. Therefore, egg production should constrain the investment in chemical defenses based on polyketides, such as benzoquinones. We tested this hypothesis using the harvestman Acutiosoma longipes, which produces large eggs and releases benzoquinones as chemical defense. We predicted that the amount of secretion released by ovigerous females (OFs would be smaller than that of non-ovigerous females (NOF. We also conducted a series of bioassays in the field and in the laboratory to test whether egg production renders OFs more vulnerable to predation. OFs produce less secretion than NOFs, which is congruent with the hypothesis that egg production constrains the investment in chemical defenses. Results of the bioassays show that the secretion released by OFs is less effective in deterring potential predators (ants and spiders than the secretion released by NOFs. In conclusion, females allocate resources to chemical defenses in a way that preserves a primary biological function related to reproduction. However, the trade-off between egg and secretion production makes OFs vulnerable to predators. We suggest that egg production is a critical moment in the life of harvestman females, representing perhaps the highest cost of reproduction in the group.

  18. Department of Defense high power laser program guidance

    Science.gov (United States)

    Muller, Clifford H.

    1994-06-01

    The DoD investment of nominally $200 million per year is focused on four high power laser (HPL) concepts: Space-Based Laser (SBL), a Ballistic Missile Defense Organization effort that addresses boost-phase intercept for Theater Missile Defense and National Missile Defense; Airborne Laser (ABL), an Air Force effort that addresses boost-phase intercept for Theater Missile Defense; Ground-Based Laser (GBL), an Air Force effort addressing space control; and Anti-Ship Missile Defense (ASMD), a Navy effort addressing ship-based defense. Each organization is also supporting technology development with the goal of achieving less expensive, brighter, and lighter high power laser systems. These activities represent the building blocks of the DoD program to exploit the compelling characteristics of the high power laser. Even though DoD's HPL program are focused and moderately strong, additional emphasis in a few technical areas could help reduce risk in these programs. In addition, a number of options are available for continuing to use the High-Energy Laser System Test Facility (HELSTF) at White Sands Missile Range. This report provides a brief overview and guidance for the five efforts which comprise the DoD HPL program (SBL, ABL, GBL, ASMD, HELSTF).

  19. Overview: Defense high-level waste technology program

    International Nuclear Information System (INIS)

    Shupe, M.W.; Turner, D.A.

    1987-01-01

    Defense high-level waste generated by atomic energy defense activities is stored on an interim basis at three U.S. Department of Energy (DOE) operating locations; the Savannah River Plant in South Carolina, the Hanford Site in Washington, and the Idaho National Engineering Laboratory in Idaho. Responsibility for the permanent disposal of this waste resides with DOE's Office of Defense Waste and Transportation Management. The objective of the Defense High-Level Wast Technology Program is to develop the technology for ending interim storage and achieving permanent disposal of all U.S. defense high-level waste. New and readily retrievable high-level waste are immobilized for disposal in a geologic repository. Other high-level waste will be stabilized in-place if, after completion of the National Environmental Policy Act (NEPA) process, it is determined, on a site-specific basis, that this option is safe, cost effective and environmentally sound. The immediate program focus is on implementing the waste disposal strategy selected in compliance with the NEPA process at Savannah River, while continuing progress toward development of final waste disposal strategies at Hanford and Idaho. This paper presents an overview of the technology development program which supports these waste management activities and an assessment of the impact that recent and anticipated legal and institutional developments are expected to have on the program

  20. Federal Aviation Administration's behavioral research program for defense against hijackings.

    Science.gov (United States)

    Dailey, J T; Pickrel, E W

    1975-04-01

    Behavioral research has been significant contributions to the government's successful program for defense against hijackers. Today's boarding gate defenses have a leading role in that program, but they were rejected until creation of the behavioral profile made selective search feasible. Metal detectors now make search of all travelers practical but with increasing involvement of boarding gate employees, so a behavioral program is used to monitor their performance. Experience shows that some persons have penetrated boarding gate defenses, so another requirement was in-flight defenses. Flightpersonnel had defeated some past hijackers, so a behavioral analysis of past hijackings was used to identify tactics for in-flight defense. These were incorporated into training programs and distributed to all U.S. airlines, many government organizations, and foreign carriers. Research continues for updating these and developing new courses for special needs, such as defense against gangs.

  1. Defense Meteorological Satellite Program (DMSP)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Defense Meteorological Satellite Program (DMSP) satellites collect visible and infrared cloud imagery as well as monitoring the atmospheric, oceanographic,...

  2. Defense Finance and Accounting Service Commercial Activities Program

    National Research Council Canada - National Science Library

    1999-01-01

    .... This report evaluated the Defense Finance and Accounting Service competitive sourcing process and reviewed the adequacy of the Defense Finance and Accounting Service management control program...

  3. Chemical and genetic defenses against disease in insect societies.

    Science.gov (United States)

    Stow, Adam; Beattie, Andrew

    2008-10-01

    The colonies of ants, bees, wasps and termites, the social insects, consist of large numbers of closely related individuals; circumstances ideal for contagious diseases. Antimicrobial assays of these animals have demonstrated a wide variety of chemical defenses against both bacteria and fungi that can be broadly classified as either external antiseptic compounds or internal immune molecules. Reducing the disease risks inherent in colonies of social insects is also achieved by behaviors, such as multiple mating or dispersal, that lower genetic relatedness both within- and among colonies. The interactions between social insects and their pathogens are complex, as illustrated by some ants that require antimicrobial and behavioral defenses against highly specialized fungi, such as those in the genus Cordyceps that attack larvae and adults and species in the genus Escovopsis that attack their food supplies. Studies of these defenses, especially in ants, have revealed remarkably sophisticated immune systems, including peptides induced by, and specific to, individual bacterial strains. The latter may be the result of the recruitment by the ants of antibiotic-producing bacteria but the extent of such three-way interactions remains unknown. There is strong experimental evidence that the evolution of sociality required dramatic increases in antimicrobial defenses and that microbes have been powerful selective agents. The antimicrobial chemicals and the insect-killing fungi may be useful in medicine and agriculture, respectively.

  4. Analysis of Defense Industry Consolidation Effects on Program Acquisition Costs

    National Research Council Canada - National Science Library

    Hoff, Russell V

    2007-01-01

    .... This thesis examines whether cost changes are evident following consolidation within the defense industry by conducting a regression analysis of Major Defense Acquisition Programs across 13 broad defense market sectors...

  5. Defense Meteorological Satellite Program (DMSP) Film

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The United States Air Force Defense Meteorological Satellite Program (DMSP) Operational Linescan System (OLS) is a polar orbiting meteorological sensor with two...

  6. 77 FR 62469 - Defense Logistics Agency Freedom of Information Act Program

    Science.gov (United States)

    2012-10-15

    ... DEPARTMENT OF DEFENSE Office of the Secretary 32 CFR Part 300 Defense Logistics Agency 32 CFR Part 1285 RIN 0790-AI87 [Docket ID: DOD-2012-OS-0019] Defense Logistics Agency Freedom of Information Act Program AGENCY: Defense Logistics Agency, DoD. ACTION: Proposed rule. SUMMARY: The Defense Logistics...

  7. Host plant invests in growth rather than chemical defense when attacked by a specialist herbivore.

    Science.gov (United States)

    Arab, Alberto; Trigo, José Roberto

    2011-05-01

    Plant defensive compounds may be a cost rather than a benefit when plants are attacked by specialist insects that may overcome chemical barriers by strategies such as sequestering plant compounds. Plants may respond to specialist herbivores by compensatory growth rather than chemical defense. To explore the use of defensive chemistry vs. compensatory growth we studied Brugmansia suaveolens (Solanaceae) and the specialist larvae of the ithomiine butterfly Placidina euryanassa, which sequester defensive tropane alkaloids (TAs) from this host plant. We investigated whether the concentration of TAs in B. suaveolens was changed by P. euryanassa damage, and whether plants invest in growth, when damaged by the specialist. Larvae feeding during 24 hr significantly decreased TAs in damaged plants, but they returned to control levels after 15 days without damage. Damaged and undamaged plants did not differ significantly in leaf area after 15 days, indicating compensatory growth. Our results suggest that B. suaveolens responds to herbivory by the specialist P. euryanassa by investing in growth rather than chemical defense.

  8. Department of Defense Joint Chemical and Biological Defense Program 2009 Annual Report to Congress

    Science.gov (United States)

    2009-03-27

    private sector all partner with the DoD CBDP to fulfill its mission to provide CBRN defense capabilities in support of the National Military Strategies...Venezuelan, and Eastern Equine Encephalitis) delivered by electroporation which showed high efficacy in non-human primates. Developed five technology

  9. Civil Defense, U. S. A.: A Programmed Orientation to Civil Defense. Unit 4. Warning, Emergency Operations, and Support Programs.

    Science.gov (United States)

    Defense Civil Preparedness Agency (DOD), Battle Creek, MI.

    The need for, and a description of, emergency functions required to save lives and protect property in nuclear or natural disasters are presented. Topics discussed include: (1) The Civil Defense Warning System, (2) Introduction to the Emergency Operations Program, (3) Five subprograms of the Emergency Operations Program, (4) Emergency Operations…

  10. Study of the Department of Defense Student Testing Program

    National Research Council Canada - National Science Library

    Davidson, Lance G

    2005-01-01

    ...) Career Exploration Program (CEP) and its contributions to Navy recruiting. The ASVAB-CEP is a Department of Defense program created in 1968, operating in 12,598 high schools throughout the nation as of 2004...

  11. Defense program pushes microchip frontiers

    Science.gov (United States)

    Julian, K.

    1985-05-01

    The very-high-speed integrated circuit (VHSIC) program of the Department of Defense will have a significant effect on the expansion of integrated circuit technology. This program, which is to cost several hundred million dollars, is accelerating the trend toward higher-speed, denser circuitry for microchips through innovative design and fabrication techniques. Teams in six different American companies are to design and fabricate a military useful 'brassboard' system which would employ chips developed in the first phase of the VHSIC program. Military objectives envisaged include automatic monitoring of displays in tactical aircraft by means of an artificial intelligence system, a brassboard used in airborne electronic warfare system, and antisubmarine warfare applications. After a fivefold improvement in performance achieved in the first phase, the second phase is concerned with a further 20-fold increase. The entire VHSIC program is, therefore, to produce a 100-fold gain over the state of the art found when the program started.

  12. Evolutionary potential of root chemical defense: genetic correlations with shoot chemistry and plant growth.

    Science.gov (United States)

    Parker, J D; Salminen, J-P; Agrawal, Anurag A

    2012-08-01

    Root herbivores can affect plant fitness, and roots often contain the same secondary metabolites that act as defenses in shoots, but the ecology and evolution of root chemical defense have been little investigated. Here, we investigated genetic variance, heritability, and correlations among defensive phenolic compounds in shoot vs. root tissues of common evening primrose, Oenothera biennis. Across 20 genotypes, there were roughly similar concentrations of total phenolics in shoots vs. roots, but the allocation of particular phenolics to shoots vs. roots varied along a continuum of genotype growth rate. Slow-growing genotypes allocated 2-fold more of the potential pro-oxidant oenothein B to shoots than roots, whereas fast-growing genotypes had roughly equivalent above and belowground concentrations. Phenolic concentrations in both roots and shoots were strongly heritable, with mostly positive patterns of genetic covariation. Nonetheless, there was genotype-specific variation in the presence/absence of two major ellagitannins (oenothein A and its precursor oenothein B), indicating two different chemotypes based on alterations in this chemical pathway. Overall, the presence of strong genetic variation in root defenses suggests ample scope for the evolution of these compounds as defenses against root herbivores.

  13. Radionuclide separations and processing for defense water management

    International Nuclear Information System (INIS)

    Fryberger, T.B.

    1993-01-01

    An overview is given of the Department of Energy's Efficient Separations and Processing Integrated Program (ESPIP). This program sponsors research in advanced chemical separations for removal of radionuclides and hazardous components from radioactive defense wastes. Separations processing will reduce the volume of high-level waste that must be disposed of in a deep geological repository and will improve the quality of low-level wastes acceptable for near-surface disposal. DOE defense complex processing needs as well as technologies that are currently under development in the program are discussed

  14. FY 1972-1976 Defense Program and the 1972 Defense Budget.

    Science.gov (United States)

    1971-03-01

    Thai Government. This assessment was given me by Thai officials during my recent visit there. Insurgents along the Thai/ Malaysian border are under the...Development and Initial Procurement of Maverick Air-to-Ground Missile 31 87 Air Superiority and Air Defense Continued Procurement of F-4 Air Force Fighter... MAVERICK . The MAVERICK is another program that is of importance in providing increased capabilities for support of troops on the battlefield. MAVERICK is

  15. Review of flat panel display programs and defense applications

    Science.gov (United States)

    Gnade, Bruce; Schulze, Raymond; Henderson, Girardeau L.; Hopper, Darrel G.

    1997-07-01

    Flat panel display research has comprised a substantial portion of the national investment in new technology for economic and national security for the past nine years. These investments have ben made principally via several Defense Advanced Research Projects Agency (DARPA) programs, known collectively as the continuing High Definition Systems Program, and the Office of the Secretary of Defense Production Act Title III Program. Using input from the Army, Navy, and Air Force to focus research and identify insertion opportunities, DARPA and the Title III Program Office have made investments to develop the national technology base and manufacturing infrastructure necessary to meet the twin challenge of providing affordable displays in current systems and enabling the DoD strategy of winning future conflicts by getting more information to all participants during the battle. These research programs are reviewed and opportunities for applications are described. Future technology development, transfer, and transition requirements are identified. Strategy and vision are documented to assist the identification of areas meriting further consideration.

  16. Fitness costs of chemical defense in Plantago lanceolata L.: effects of nutrient and competition stress

    NARCIS (Netherlands)

    Marak, H.B.; Biere, A.; Van Damme, J.M.M.

    2003-01-01

    Fitness costs of defense are often invoked to explain the maintenance of genetic variation in levels of chemical defense compounds in natural plant populations. We investigated fitness costs of iridoid glycosides (IGs), terpenoid compounds that strongly deter generalist insect herbivores, in ribwort

  17. Defense Meteorological Satellite Program (DMSP) - Space Weather Sensors

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Defense Meteorological Satellite Program (DMSP) maintains a constellation of sun-synchronous, near-polar orbiting satellites. The orbital period is 101 minutes...

  18. Programs that support non-proliferation and defense conversion funded by the US Government

    International Nuclear Information System (INIS)

    Rutkowski, H.L.

    1994-08-01

    The proliferation of nuclear, chemical, and biological weapons is a serious problem for international security. Consequently the U.S. government has established an array of programs to fund activities that will inhibit this activity. The problem of proliferation and defense conversion, in general, is quite complicated. The most immediate concern is the actual diversion of weapons materials. In the long term; however, weapons of mass destruction must be destroyed in a safe and environmentally sound manner. Ultimately the solution of the proliferation problem lies in the redirection of the intellectual skills of weapons scientists and engineers to peaceful commercial activities. At the present time the economic conditions in the New Independent States create severe pressure on people with critical weapons knowledge to sell their skills to political entities that are dangerous. There are four programs to be discussed in this paper. The first is the open-quotes Nunn-Lugarclose quotes program which is the largest and is administered by the Department of Defense. Between FY92 and FY94 Congress authorized $1.2B for this activity which is aimed at weapons destruction, storage, and safeguards. The second is the International Science and Technology Center in Moscow and the Science Center about to open in Ukraine. These are joint efforts involving the U.S., the European Community, and Japan to fund projects to prevent proliferation and foster commercial technological activity in Russia, Georgia, and Ukraine. The New Independent States - Industrial Partnering Program is a $35M (FY94) program jointly administered by the Department of Energy and the Department of State

  19. U.S. Department of Energy defense waste management program implementation plan

    International Nuclear Information System (INIS)

    Jordan, E.A.

    1988-01-01

    The Program Implementation Plan describes the Department of Energy's current approach to managing its defense high-level, low-level, and transuranic radioactive waste. It documents implementation of the policies described in the 1983 Defense Waste Management Plan

  20. Chemical and biological warfare. Should defenses be researched and deployed?

    Science.gov (United States)

    Orient, J M

    1989-08-04

    The threat of chemical and biological weapons of mass destruction has intensified because of improved delivery systems and advances in chemistry, genetics, and other sciences. Possible US responses to this threat include deterrence, defenses, and/or disarmament, including a reaffirmation of the Biological and Toxin Weapons Convention of 1972, which is now in jeopardy. This article discusses the history of chemical and biological warfare, existing and potential weapons, the proliferation of weapons and delivery systems, ways to prevent the use of these weapons, and ways to protect populations from their effects.

  1. Family matters: effect of host plant variation in chemical and mechanical defenses on a sequestering specialist herbivore.

    Science.gov (United States)

    Dimarco, Romina D; Nice, Chris C; Fordyce, James A

    2012-11-01

    Insect herbivores contend with various plant traits that are presumed to function as feeding deterrents. Paradoxically, some specialist insect herbivores might benefit from some of these plant traits, for example by sequestering plant chemical defenses that herbivores then use as their own defense against natural enemies. Larvae of the butterfly species Battus philenor (L.) (Papilionidae) sequester toxic alkaloids (aristolochic acids) from their Aristolochia host plants, rendering larvae and adults unpalatable to a broad range of predators. We studied the importance of two putative defensive traits in Aristolochia erecta: leaf toughness and aristolochic acid content, and we examined the effect of intra- and interplant chemical variation on the chemical phenotype of B. philenor larvae. It has been proposed that genetic variation for sequestration ability is "invisible to natural selection" because intra- and interindividual variation in host-plant chemistry will largely eliminate a role for herbivore genetic variation in determining an herbivore's chemical phenotype. We found substantial intra- and interplant variation in leaf toughness and in the aristolochic acid chemistry in A. erecta. Based on field observations and laboratory experiments, we showed that first-instar larvae preferentially fed on less tough, younger leaves and avoided tougher, older leaves, and we found no evidence that aristolochic acid content influenced first-instar larval foraging. We found that the majority of variation in the amount of aristolochic acid sequestered by larvae was explained by larval family, not by host-plant aristolochic acid content. Heritable variation for sequestration is the predominant determinant of larval, and likely adult, chemical phenotype. This study shows that for these highly specialized herbivores that sequester chemical defenses, traits that offer mechanical resistance, such as leaf toughness, might be more important determinants of early-instar larval

  2. U.S. Department of Energy, defense waste management program implementation plan

    International Nuclear Information System (INIS)

    Chee, T.

    1988-01-01

    This paper reports that the program implementation plan describes the Department of Energy's current approach to managing its defense high-level, low-level, and transuranic radioactive waste. It documents implementation of the policies described in the 1983 Defense Waste Management Plan

  3. Defense Programs Transportation Risk Assessment

    International Nuclear Information System (INIS)

    Clauss, D.B.

    1994-01-01

    This paper provides an overview of the methodology used in a probabilistic transportation risk assessment conducted to assess the probabilities and consequences of inadvertent dispersal of radioactive materials arising from severe transportation accidents. The model was developed for the Defense Program Transportation Risk Assessment (DPTRA) study. The analysis incorporates several enhancements relative to previous risk assessments of hazardous materials transportation including newly-developed statistics on the frequencies and severities of tractor semitrailer accidents and detailed route characterization using the 1990 Census data

  4. Rock mechanics contributions from defense programs

    International Nuclear Information System (INIS)

    Heuze, F.E.

    1992-02-01

    An attempt is made at illustrating the many contributions to rock mechanics from US defense programs, over the past 30-plus years. Large advances have been achieved in the technology-base area covering instrumentation, material properties, physical modeling, constitutive relations and numerical simulations. In the applications field, much progress has been made in understanding and being able to predict rock mass behavior related to underground explosions, cratering, projectile penetration, and defense nuclear waste storage. All these activities stand on their own merit as benefits to national security. But their impact is even broader, because they have found widespread applications in the non-defense sector; to name a few: the prediction of the response of underground structures to major earthquakes, the physics of the earth's interior at great depths, instrumentation for monitoring mine blasting, thermo-mechanical instrumentation useful for civilian nuclear waste repositories, dynamic properties of earthquake faults, and transient large-strain numerical modeling of geological processes, such as diapirism. There is not pretense that this summary is exhaustive. It is meant to highlight success stories representative of DOE and DOD geotechnical activities, and to point to remaining challenges

  5. Defense Coastal/Estuarine Research Program (DCERP)

    Science.gov (United States)

    2007-09-19

    activities, splash points and Landing Craft Air Cushion (LCAC) operations) and non-military Base activities (e.g., sewage treatment , storm water runoff and...We will measure the metabolism of benthic microalgae, the water column, eelgrass, and any dominant macroalgae by developing series of photosynthesis...activities (storm water control and sewage treatment ). Defense Coastal/Estuarine Research Program (DCERP) Research Plan DCERP Research Plan 32 September 19

  6. Heliotropium huascoense resin exudate: chemical constituents and defensive properties.

    Science.gov (United States)

    Villarroel, L; Torres, R; Urzúa, A; Reina, M; Cabrera, R; González-Coloma, A

    2001-09-01

    From the resinous exudate of Heliotropium huascoense a new compound, rel-(8R,9R)-carrizaloic acid, (1) (3-[rel-(8R,9R-9-hydroxy-9,13,13-trimethyl-12-oxo-10-cyclohexenyl)methyl]-4-methoxybenzoic acid), and three known flavonoids, [3-methylgalangin, 3,7-dimethylgalangin, and (-)-alpinone] have been isolated. The structure of 1 was determined by spectral and chemical methods. Several plant defensive properties of 1 (insecticidal and antifungal) have been evaluated.

  7. Defense Special Weapons Agency Advisory Panel on the Nuclear Weapon Effects Program

    National Research Council Canada - National Science Library

    1998-01-01

    We performed the audit in response to allegations made to the Defense Hotline concerning conflicts of interest among members of the Defense Special Weapons Agency Advisory Panel on the Nuclear Weapon Effects Program...

  8. Overview of the Defense Programs Research and Technology Development Program for fiscal year 1993. Appendix II research laboratories and facilities

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-30

    This document contains summaries of the research facilities that support the Defense Programs Research and Technology Development Program for FY 1993. The nine program elements are aggregated into three program clusters as follows: (1) Advanced materials sciences and technologies; chemistry and materials, explosives, special nuclear materials (SNM), and tritium. (2) Design sciences and advanced computation; physics, conceptual design and assessment, and computation and modeling. (3) Advanced manufacturing technologies and capabilities; system engineering science and technology, and electronics, photonics, sensors, and mechanical components. Section I gives a brief summary of 23 major defense program (DP) research and technology facilities and shows how these major facilities are organized by program elements. Section II gives a more detailed breakdown of the over 200 research and technology facilities being used at the Laboratories to support the Defense Programs mission.

  9. Major Management Challenges and Program Risks Department of Defense

    National Research Council Canada - National Science Library

    1999-01-01

    .... The report also addresses corrective actions that DOD has taken or initiated on these issues- including DOD'S blueprint for a strategy-based, balanced, and affordable defense program as outlined...

  10. Chemical Stockpile Disposal Program

    Energy Technology Data Exchange (ETDEWEB)

    Krummel, J.R.; Policastro, A.J.; Olshansky, S.J.; McGinnis, L.D.

    1990-10-01

    As part of the Chemical Stockpile Disposal Program mandated by Public Law 99--145 (Department of Defense Authorization Act), an independent review is presented of the US Army Phase I environmental report for the disposal program at the Umatilla Depot Activity (UMDA) in Hermiston, Oregon. The Phase I report addressed new and additional concerns not incorporated in the final programmatic environmental impact statement (FPEIS). Those concerns were addressed by examining site-specific data for the Umatilla Depot Activity and by recommending the scope and content of a more detailed site-specific study. This independent review evaluates whether the new site-specific data presented in the Phase I report would alter the decision in favor of on-site disposal that was reached in the FPEIS, and whether the recommendations for the scope and content of the site-specific study are adequate. Based on the methods and assumptions presented in the FPEIS, the inclusion of more detailed site-specific data in the Phase I report does not change the decision reached in the FPEIS (which favored on-site disposal at UMDA). It is recommended that alternative assumptions about meteorological conditions be considered and that site-specific data on water, ecological, socioeconomic, and cultural resources; seismicity; and emergency planning and preparedness be considered explicitly in the site-specific EIS decision-making process. 7 refs., 1 fig.

  11. Safe shutdown of Defense Program facilities at the Mound Plant, Miamisburg, Ohio

    International Nuclear Information System (INIS)

    Anderson, H.F.; Bantz, P.D.; Luthy, D.F.

    1996-01-01

    The Mound Plant was one of several production sites in the US Department of Energy's Defense Programs (DP) Weapons Complex. As a result of the downsizing of the weapons program, certain operations at Mound are being transferred to other DOE sites and the DP buildings at Mound are being shutdown. The objectives of the program are to reduce the hazardous and financial liabilities to DOE and to foster the reuse of facilities for economic development. The overall program is described. The process began with the categorization of excess DP buildings into three groups depending on their anticipated future use. The draft DOE/EM-60 Acceptance Criteria were used to develop a detailed shutdown checklist as the foundation of the process. The overall program budget, schedule, ad options for disposition of materials and components is presented. Accomplishments in FY94 and FY95 are described. By the end of FY95, all excess energetic materials and components, all excess chemicals (from non-radiation areas) and significant amounts of radioactive materials have been removed from the site. By the end of FY95, 47 of the 72 buildings in the program have been taken through all ten of the draft EM-60 acceptance criteria. Lessons learned, based on experience at Mound to date, are summarized

  12. Second Line of Defense Spares Program

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, Dale L.; Holmes, Aimee E.; Muller, George; Mercier, Theresa M.; Brigantic, Robert T.; Perkins, Casey J.; Cooley, Scott K.; Thorsen, Darlene E.

    2012-11-20

    During Fiscal Year 2012, a team from the Pacific Northwest National Laboratory (PNNL) conducted an assessment and analysis of the Second Line of Defense (SLD) Sustainability spare parts program. Spare parts management touches many aspects of the SLD Sustainability Program including contracting and integration of Local Maintenance Providers (LMP), equipment vendors, analyses and metrics on program performance, system state of health, and maintenance practices. Standardized spares management will provide better data for decisions during site transition phase and will facilitate transition to host country sustainability ownership. The effort was coordinated with related SLD Sustainability Program initiatives, including a configuration items baselining initiative, a metrics initiative, and a maintenance initiative. The spares study has also led to pilot programs for sourcing alternatives that include regional intermediate inventories and partnering agreements that leverage existing supply chains. Many partners from the SLD Sustainability program contributed to and were consulted in the course of the study. This document provides a description of the findings, recommendations, and implemented solutions that have resulted from the study.

  13. DOE Defense Program (DP) safety programs. Final report, Task 003

    International Nuclear Information System (INIS)

    1998-01-01

    The overall objective of the work on Task 003 of Subcontract 9-X52-W7423-1 was to provide LANL with support to the DOE Defense Program (DP) Safety Programs. The effort included the identification of appropriate safety requirements, the refinement of a DP-specific Safety Analysis Report (SAR) Format and Content Guide (FCG) and Comprehensive Review Plan (CRP), incorporation of graded approach instructions into the guidance, and the development of a safety analysis methodologies document. All tasks which were assigned under this Task Order were completed. Descriptions of the objectives of each task and effort performed to complete each objective is provided here

  14. Quality Assurance Program description, Defense Waste Processing Facility (DWPF)

    International Nuclear Information System (INIS)

    Maslar, S.R.

    1992-01-01

    This document describes the Westinghouse Savannah River Company's (WSRC) Quality Assurance Program for Defense Waste Processing at the Savannah River Site (SRS). WSRC is the operating contractor for the US Department of Energy (DOE) at the SRS. The following objectives are achieved through developing and implementing the Quality Assurance Program: (1) Ensure that the attainment of quality (in accomplishing defense high-level waste processing objectives at the SRS) is at a level commensurate with the government's responsibility for protecting public health and safety, the environment, the public investment, and for efficiently and effectively using national resources. (2) Ensure that high-level waste from qualification and production activities conform to requirements defined by OCRWM. These activities include production processes, equipment, and services; and products that are planned, designed, procured, fabricated, installed, tested, operated, maintained, modified, or produced

  15. Leaf habit does not determine the investment in both physical and chemical defences and pair-wise correlations between these defensive traits.

    Science.gov (United States)

    Moreira, X; Pearse, I S

    2017-05-01

    Plant life-history strategies associated with resource acquisition and economics (e.g. leaf habit) are thought to be fundamental determinants of the traits and mechanisms that drive herbivore pressure, resource allocation to plant defensive traits, and the simultaneous expression (positive correlations) or trade-offs (negative correlations) between these defensive traits. In particular, it is expected that evergreen species - which usually grow slower and support constant herbivore pressure in comparison with deciduous species - will exhibit higher levels of both physical and chemical defences and a higher predisposition to the simultaneous expression of physical and chemical defensive traits. Here, by using a dataset which included 56 oak species (Quercus genus), we investigated whether leaf habit of plant species governs the investment in both physical and chemical defences and pair-wise correlations between these defensive traits. Our results showed that leaf habit does not determine the production of most leaf physical and chemical defences. Although evergreen oak species had higher levels of leaf toughness and specific leaf mass (physical defences) than deciduous oak species, both traits are essentially prerequisites for evergreenness. Similarly, our results also showed that leaf habit does not determine pair-wise correlations between defensive traits because most physical and chemical defensive traits were simultaneously expressed in both evergreen and deciduous oak species. Our findings indicate that leaf habit does not substantially contribute to oak species differences in plant defence investment. © 2017 German Botanical Society and The Royal Botanical Society of the Netherlands.

  16. Lasers and particle beam for fusion and strategic defense

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    This special issue of the Journal of Fusion Energy consists of the edited transscripts of a symposium on the applications of laser and particle beams to fusion and strategic defense. Its eleven papers discuss these topics: the Strategic Defense Initiative; accelerators for heavy ion fusion; rf accelerators for fusion and strategic defense; Pulsed power, ICF, and the Strategic Defense Initiative; chemical lasers; the feasibility of KrF lasers for fusion; the damage resistance of coated optic; liquid crystal devices for laser systems; fusion neutral-particle beam research and its contribution to the Star Wars program; and induction linacs and free electron laser amplifiers for ICF devices and directed-energy weapons

  17. Searching the Skies: the Legacy of the United States Cold War Defense Radar Program

    National Research Council Canada - National Science Library

    Winkler, David

    1997-01-01

    The Department of Defense (DOD) Legacy Resource Management Program was established under the Defense Appropriations Act of 1991 to determine how to better integrate the conservation of irreplaceable biological, cultural...

  18. Development of fusion fuel cycles: Large deviations from US defense program systems

    Energy Technology Data Exchange (ETDEWEB)

    Klein, James Edward, E-mail: james.klein@srnl.doe.gov; Poore, Anita Sue; Babineau, David W.

    2015-10-15

    Highlights: • All tritium fuel cycles start with a “Tritium Process.” All have similar tritium processing steps. • Fusion tritium fuel cycles minimize process tritium inventories for various reasons. • US defense program facility designs did not minimize in-process inventories. • Reduced inventory tritium facilities will lower public risk. - Abstract: Fusion energy research is dominated by plasma physics and materials technology development needs with smaller levels of effort and funding dedicated to tritium fuel cycle development. The fuel cycle is necessary to supply and recycle tritium at the required throughput rate; additionally, tritium confinement throughout the facility is needed to meet regulatory and environmental release limits. Small fuel cycle development efforts are sometimes rationalized by stating that tritium processing technology has already been developed by nuclear weapons programs and these existing processes only need rescaling or engineering design to meet the needs of fusion fuel cycles. This paper compares and contrasts features of tritium fusion fuel cycles to United States Cold War era defense program tritium systems. It is concluded that further tritium fuel cycle development activities are needed to provide technology development beneficial to both fusion and defense programs tritium systems.

  19. Strategic Defense Initiative Organization adaptive structures program overview

    Science.gov (United States)

    Obal, Michael; Sater, Janet M.

    In the currently envisioned architecture none of the Strategic Defense System (SDS) elements to be deployed will receive scheduled maintenance. Assessments of performance capability due to changes caused by the uncertain effects of environments will be difficult, at best. In addition, the system will have limited ability to adjust in order to maintain its required performance levels. The Materials and Structures Office of the Strategic Defense Initiative Organization (SDIO) has begun to address solutions to these potential difficulties via an adaptive structures technology program that combines health and environment monitoring with static and dynamic structural control. Conceivable system benefits include improved target tracking and hit-to-kill performance, on-orbit system health monitoring and reporting, and threat attack warning and assessment.

  20. Antipredator defenses predict diversification rates

    Science.gov (United States)

    Arbuckle, Kevin; Speed, Michael P.

    2015-01-01

    The “escape-and-radiate” hypothesis predicts that antipredator defenses facilitate adaptive radiations by enabling escape from constraints of predation, diversified habitat use, and subsequently speciation. Animals have evolved diverse strategies to reduce the direct costs of predation, including cryptic coloration and behavior, chemical defenses, mimicry, and advertisement of unprofitability (conspicuous warning coloration). Whereas the survival consequences of these alternative defenses for individuals are well-studied, little attention has been given to the macroevolutionary consequences of alternative forms of defense. Here we show, using amphibians as the first, to our knowledge, large-scale empirical test in animals, that there are important macroevolutionary consequences of alternative defenses. However, the escape-and-radiate hypothesis does not adequately describe them, due to its exclusive focus on speciation. We examined how rates of speciation and extinction vary across defensive traits throughout amphibians. Lineages that use chemical defenses show higher rates of speciation as predicted by escape-and-radiate but also show higher rates of extinction compared with those without chemical defense. The effect of chemical defense is a net reduction in diversification compared with lineages without chemical defense. In contrast, acquisition of conspicuous coloration (often used as warning signals or in mimicry) is associated with heightened speciation rates but unchanged extinction rates. We conclude that predictions based on the escape-and-radiate hypothesis must incorporate the effect of traits on both speciation and extinction, which is rarely considered in such studies. Our results also suggest that knowledge of defensive traits could have a bearing on the predictability of extinction, perhaps especially important in globally threatened taxa such as amphibians. PMID:26483488

  1. Second Line of Defense Spares Program Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, Dale L.; Muller, George; Mercier, Theresa M.; Brigantic, Robert T.; Perkins, Casey J.; Cooley, Scott K.

    2012-11-20

    The Office of the Second Line of Defense (SLD) is part of the Department of Energy‘s (DOE) National Nuclear Security Administration (NNSA). The SLD Program accomplishes its critical global security mission by forming cooperative relationships with partner countries to install passive radiation detection systems that augment traditional inspection and law enforcement measures by alerting border officials to the presence of special nuclear or other radiological materials in cross-border traffic. An important tenet of the program is to work collaboratively with these countries to establish the necessary processes, procedures, infrastructure and conditions that will enable them to fully assume the financial and technical responsibilities for operating the equipment. As the number of operational deployments grows, the SLD Program faces an increasingly complex logistics process to promote the timely and efficient supply of spare parts.

  2. Defense Health Program Financial Reporting of General Property, Plant, and Equipment

    National Research Council Canada - National Science Library

    Lane, F

    2000-01-01

    .... The Defense Health Program funds the operations of the Military Departments' medical treatment facilities, the development of DoD medical systems software, and congressionally directed research...

  3. FY 1987 program summary document: Office of Defense Waste and Transportation Management

    International Nuclear Information System (INIS)

    1987-04-01

    This document describes the Office of Defense Waste and Transportation Management (DWTM) Program as supported by the President's Fiscal Year (FY) 1987 Budget Request to Congress. It specifically addresses the program's organization, objectives, strategies, and plans for FY 1987

  4. Defense Logistics Agency Disposition Services Needs to Improve Demilitarization Program Self-Assessment Evaluations - Redacted

    Science.gov (United States)

    2016-12-20

    from mandatory disclosure under the Freedom of Information Act. Defense Logistics Agency Disposition Services Needs to Improve Demilitarization...Project No. D2016-D000RD-0057.000) │ i Results in Brief Defense Logistics Agency Disposition Services Needs to Improve Demilitarization Program Self...Assessment Evaluations Visit us at www.dodig.mil December 20, 2016 Objective Our audit objective was to determine whether the Defense Logistics Agency

  5. Defense Coastal/Estuarine Research Program 2 (DCERP2)

    Science.gov (United States)

    2013-05-01

    Assessing TMDL effectiveness using flow-adjusted concentrations:  A case study of the Neuse River , North Carolina. Environmental Science & Technology 37...activities, and data collection in the NRE Basin and New River by local stakeholder groups. Defense Coastal/Estuarine Research Program (DCERP) Monitoring...relationships between light penetration and solids/chl a levels. ArcGIS and spatial statistics will be used to estimate average bathymetric areas

  6. Defense Coastal/Estuarine Research Program (DCERP) Strategic Plan

    Science.gov (United States)

    2007-09-01

    availability to phytoplankton in the water column, as well as to benthic microalgae, macroalgae , and seagrasses in bottom waters (Gallegos et al., 2005...further another of MCBCL’s key management objectives for meeting the requirements of the CWA. How wetlands may be utilized for water treatment ...Regulations Appendix B Prioritized list of MCBCL’s conservation and water quality needs Defense Coastal/Estuarine Research Program (DCERP) Strategic

  7. Defense Infrastructure: Continuing Challenges in Managing DOD Lodging Programs as Army Moves to Privatize Its Program

    National Research Council Canada - National Science Library

    Holman, Barry W; Kennedy, Michael; Dickey, Claudia; Lenane, Kate; Sarapu, Leslie; Silvers, Julie; Weissman, Cheryl

    2006-01-01

    The Department of Defense (DoD) transient lodging programs were established to provide quality temporary facilities for authorized personnel, and to reduce travel costs through lower rates than commercial hotels...

  8. Implementing Effective Affordability Constraints for Defense Acquisition Programs

    Science.gov (United States)

    2014-03-01

    version that appears in the Pentagon Digital Library at http://www.whs.mil/library/mildoc/DODD.html. See also Joe Ferrara , “DOD’s 5000 Documents...costs.16 E. MIDS MIDS is a multinational (United States, France, Germany, Italy , Spain) cooperative development program with U.S. Joint Service...Congressional Research Service, 15 January 2014. Ferrara , Joe. “DOD’s 5000 Documents: Evolution and Change in Defense Acquisition Policy.” Acquisition

  9. The Department of Defense FY 1998 Small Business Innovation Research (SBIR) Program. Program Solicitation 98.2

    National Research Council Canada - National Science Library

    1998-01-01

    ...), and Office of the Secretary of Defense (OSD), hereafter referred to as DoD Components, invite small business firms to submit proposals under this solicitation for the Small Business Innovation Research (SBIR) program...

  10. Developing the strategic plan for pollution prevention in defense programs

    International Nuclear Information System (INIS)

    Marchetti, John A.; Betschart, James F.; Suffern, J. Samuel

    1992-01-01

    In order to provide effective leadership and to ensure a consistent pollution prevention effort in all of its production facilities and laboratories, Defense Programs (DP) Headquarters, in close cooperation with the Field, has developed a strategic plan for its Pollution Prevention Program. The strategic plan is built upon the history of waste minimization, waste reduction, and pollution prevention activity to date, and articulates both long- and short-term strategies to ensure program initiation, growth, and stability. The organization of the program, including Headquarters staffing and linkages to the Geld, is described. Life-cycle analysis of program barriers and bottlenecks, along with associated initiatives and action plans are discussed. (author)

  11. Antibacterial activity of the sponge Suberites domuncula and its primmorphs: Potential basis for epibacterial chemical defense

    Digital Repository Service at National Institute of Oceanography (India)

    Thakur, N; Hentschel, U.; Krasko, A; Pabel, C; Anil, A.C; Mueller, W.E.G.

    The epibacterial chemical defense of the marine sponge Suberites domuncula was explored by screening sponge extract, sponge primmorph (3-D aggregates containing proliferating cells) extract and sponge-associated as well as primmorph...

  12. Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae).

    Science.gov (United States)

    Makarov, Slobodan E; Bodner, Michaela; Reineke, Doris; Vujisić, Ljubodrag V; Todosijević, Marina M; Antić, Dragan Ž; Vagalinski, Boyan; Lučić, Luka R; Mitić, Bojan M; Mitov, Plamen; Anđelković, Boban D; Lucić, Sofija Pavković; Vajs, Vlatka; Tomić, Vladimir T; Raspotnig, Günther

    2017-04-01

    Cave animals live under highly constant ecological conditions and in permanent darkness, and many evolutionary adaptations of cave-dwellers have been triggered by their specific environment. A similar "cave effect" leading to pronounced chemical interactions under such conditions may be assumed, but the chemoecology of troglobionts is mostly unknown. We investigated the defensive chemistry of a largely cave-dwelling julid group, the controversial tribe "Typhloiulini", and we included some cave-dwelling and some endogean representatives. While chemical defense in juliform diplopods is known to be highly uniform, and mainly based on methyl- and methoxy-substituted benzoquinones, the defensive secretions of typhloiulines contained ethyl-benzoquinones and related compounds. Interestingly, ethyl-benzoquinones were found in some, but not all cave-dwelling typhloiulines, and some non-cave dwellers also contained these compounds. On the other hand, ethyl-benzoquinones were not detected in troglobiont nor in endogean typhloiuline outgroups. In order to explain the taxonomic pattern of ethyl-benzoquinone occurrence, and to unravel whether a cave-effect triggered ethyl-benzoquinone evolution, we classed the "Typhloiulini" investigated here within a phylogenetic framework of julid taxa, and traced the evolutionary history of ethyl-benzoquinones in typhloiulines in relation to cave-dwelling. The results indicated a cave-independent evolution of ethyl-substituted benzoquinones, indicating the absence of a "cave effect" on the secretions of troglobiont Typhloiulini. Ethyl-benzoquinones probably evolved early in an epi- or endogean ancestor of a clade including several, but not all Typhloiulus (basically comprising a taxonomic entity known as "Typhloiulus sensu stricto") and Serboiulus. Ethyl-benzoquinones are proposed as novel and valuable chemical characters for julid systematics.

  13. Defesas químicas de plantas: fitoalexinas Chemical defense of plants: phytoalexins

    Directory of Open Access Journals (Sweden)

    Márcia Regina Braga

    1987-01-01

    Full Text Available A resistência de plantas ao ataque de microorganismos causadores de doenças relaciona-se à presença de barreiras físicas e (juímicas de defesa. Dentre as barreiras químicas destacam-se as fitoalexinas, substâncias fungitoxicas sintetizadas de novo pelas plantas principalmente após a invasão ou o contato de seus tecidos com microorganismos, Essas substâncias englobam vários grupos compostos naturais tais como terpenos, isoflavonóides e poliacetilenos e seu acúmulo pode ser induzido por organismos vivos, seus produtos (elíciadores ou ainda agentes químicos, como sais de metais pesados, ou físicos (congelamento, luz U.U.. Alguns aspectos abordados nesta revisão são: a ocorrência de fitoalexinas em angiospermas, a relação entre sua natureza química e o grupo taxonômico das plantas que as produzem, a sua ação sobre organismos pró e eucarióticos. São descritas também os fatores que interferem nas respostas das plantas aos agentes indutores e as técnicas usuais para a indução e detecção de fitoalexinas. O papel dos eliciadores na indução da sâitese de fitoalexinas e o mecanismo pelo qual exercem sua função indutora são discutidos. Nesse contexto está incluída a teoria das oligossacarinas, fragmentos de parede celular que parecem controlar não só a resposta de defesa em plantas mas também outros fenômenos fisiológicos em plantas.Chemical defense of plants: phytoalexins - This review describes the concept of phytoalexins as a chemical defense of plants against microorganisms as well as a response of plants to chemical or physical agents. The current information on phytoalexins is presented, regarding the following aspects: occurrence in angiosperms; relation-snips between chemical composition and taxonomy; toxicity; factors affecting plant response; techniques for induction and detection of phytoalexins; role of elicitors and mechanisms of action. The latter includes the oligosaccharins-fragments of cell

  14. Statistical process control support during Defense Waste Processing Facility chemical runs

    International Nuclear Information System (INIS)

    Brown, K.G.

    1994-01-01

    The Product Composition Control System (PCCS) has been developed to ensure that the wasteforms produced by the Defense Waste Processing Facility (DWPF) at the Savannah River Site (SRS) will satisfy the regulatory and processing criteria that will be imposed. The PCCS provides rigorous, statistically-defensible management of a noisy, multivariate system subject to multiple constraints. The system has been successfully tested and has been used to control the production of the first two melter feed batches during DWPF Chemical Runs. These operations will demonstrate the viability of the DWPF process. This paper provides a brief discussion of the technical foundation for the statistical process control algorithms incorporated into PCCS, and describes the results obtained and lessons learned from DWPF Cold Chemical Run operations. The DWPF will immobilize approximately 130 million liters of high-level nuclear waste currently stored at the Site in 51 carbon steel tanks. Waste handling operations separate this waste into highly radioactive sludge and precipitate streams and less radioactive water soluble salts. (In a separate facility, soluble salts are disposed of as low-level waste in a mixture of cement slag, and flyash.) In DWPF, the precipitate steam (Precipitate Hydrolysis Aqueous or PHA) is blended with the insoluble sludge and ground glass frit to produce melter feed slurry which is continuously fed to the DWPF melter. The melter produces a molten borosilicate glass which is poured into stainless steel canisters for cooling and, ultimately, shipment to and storage in a geologic repository

  15. Environmental evaluation of alternatives for long-term management of Defense high-level radioactive wastes at the Idaho Chemical Processing Plant

    Energy Technology Data Exchange (ETDEWEB)

    1982-09-01

    The U.S. Department of Energy (DOE) is considering the selection of a strategy for the long-term management of the defense high-level wastes at the Idaho Chemical Processing Plant (ICPP). This report describes the environmental impacts of alternative strategies. These alternative strategies include leaving the calcine in its present form at the Idaho National Engineering Laboratory (INEL), or retrieving and modifying the calcine to a more durable waste form and disposing of it either at the INEL or in an offsite repository. This report addresses only the alternatives for a program to manage the high-level waste generated at the ICPP. 24 figures, 60 tables.

  16. Environmental evaluation of alternatives for long-term management of Defense high-level radioactive wastes at the Idaho Chemical Processing Plant

    International Nuclear Information System (INIS)

    1982-09-01

    The U.S. Department of Energy (DOE) is considering the selection of a strategy for the long-term management of the defense high-level wastes at the Idaho Chemical Processing Plant (ICPP). This report describes the environmental impacts of alternative strategies. These alternative strategies include leaving the calcine in its present form at the Idaho National Engineering Laboratory (INEL), or retrieving and modifying the calcine to a more durable waste form and disposing of it either at the INEL or in an offsite repository. This report addresses only the alternatives for a program to manage the high-level waste generated at the ICPP. 24 figures, 60 tables

  17. Department of Defense Chemical and Biological Defense Program. Volume I: Annual Report to Congress

    Science.gov (United States)

    2002-04-01

    nerve agents. * Identified specific gene products that are either enhanced or depressed in the brain following low-level chemical warfare nerve agent...with ample time to properly treat for injury. This model was used to determine that N- acetylcysteine given intraperitoneally increased survival rates in

  18. Long-Term Implications of the Fiscal Year 2009 Future Years Defense Program

    National Research Council Canada - National Science Library

    Talaber, Adam; Arthur, David; Bass, Elizabeth; Bennett, Michael; Eveker, Kevin; Frisk, Daniel; Labs, Eric J; Lussier, Frances; Percy, Allison; Hall, Raymond; Newman, David; Regan, Dawn S; Schmit, Matthew; Wheelock, Jason; Kelley, Kate

    2009-01-01

    ...) has published a series of reports about its projections of the resources that might be needed over the long term to carry out the Bush Administration's plans as expressed in the Future Years Defense Program (FYDP...

  19. Department of Defense Chemical and Biological Defense Program. Annual Report to Congress

    Science.gov (United States)

    2008-05-01

    medical therapies that are active against a broad spectrum of CB threats. CPRC Interagency executive committee that reports on activities and programs...Qtr. FY 2012 Multivalent Equine Encephalitis * 1st Qtr. FY 2012 Plague Vaccine October 28, 2004 n Ricin Vaccine * 3rd Qtr. FY 2009 n Th er ap eu tic s...physiological and psychological side effects when used alone (that is, in absence of nerve agent poisoning). Neurologic Therapeutics.• Develop

  20. The US Department of Defense Hemorrhage and Resuscitation Research and Development Program.

    Science.gov (United States)

    Pusateri, Anthony E; Dubick, Michael A

    2015-08-01

    Data from recent conflicts demonstrate the continuing need for research and development focusing on hemorrhage control, fluid resuscitation, blood products, transfusion, and pathophysiologic responses to traumatic hemorrhage. The US Department of Defense Hemorrhage and Resuscitation Research and Development Program brings together US Department of Defense efforts and is coordinated with efforts of our other federal government, industry, international, and university-based partners. Military medical research has led to advances in both military and civilian trauma care. A sustained effort will be required to continue to advance the care of severely injured trauma patients.

  1. 77 FR 11367 - Defense Federal Acquisition Regulation Supplement; Extension of the Test Program for Negotiation...

    Science.gov (United States)

    2012-02-24

    ...DoD is issuing a final rule amending the Defense Federal Acquisition Regulation Supplement to extend the program period for the DoD Test Program for Negotiation of Comprehensive Small Business Subcontracting Plans.

  2. Recommendations for sampling for prevention of hazards in civil defense. On analytics of chemical, biological and radioactive contaminations. Brief instruction for the CBRN (chemical, biological, radioactive, nuclear) sampling

    International Nuclear Information System (INIS)

    Bachmann, Udo; Biederbick, Walter; Derakshani, Nahid

    2010-01-01

    The recommendation for sampling for prevention of hazards in civil defense is describing the analytics of chemical, biological and radioactive contaminations and includes detail information on the sampling, protocol preparation and documentation procedures. The volume includes a separate brief instruction for the CBRN (chemical, biological, radioactive, nuclear) sampling.

  3. Chemical defenses and resource trade-offs structure sponge communities on Caribbean coral reefs

    OpenAIRE

    Loh, Tse-Lynn; Pawlik, Joseph R.

    2014-01-01

    Chemical defenses are known to protect some species from consumers, but it is often difficult to detect this advantage at the community or ecosystem levels because of the complexity of abiotic and biotic factors that influence species abundances. We surveyed the community of sponges and sponge predators (angelfishes and parrotfishes) on coral reefs across the Caribbean ranging from heavily overfished sites to protected marine reserves. High predator abundance correlated with high abundance of...

  4. AV-8B Remanufacture Program as Part of the Audit of the Defense Acquisition Board Review Process - FY 1994

    Science.gov (United States)

    1994-06-03

    wft*:¥A:ft:i:ft& OFFICE OF THE INSPECTOR GENERAL AV-8B REMANUFACTURE PROGRAM AS PART OF THE AUDIT OF THE DEFENSE ACQUISITION BOARD...Part of the Audit of the Defense Acquisition Board Review Process - FY 1994 B. DATE Report Downloaded From the Internet: 03/23/99 C. Report’s Point...NAVY FOR RESEARCH DEVELOPMENT AND ACQUISITION SUBJECT: Audit Report on the AV-8B Remanufacture Program as Part of the Audit of the Defense

  5. Maternal programming of defensive responses through sustained effects on gene expression.

    Science.gov (United States)

    Zhang, Tie-Yuan; Bagot, Rose; Parent, Carine; Nesbitt, Cathy; Bredy, Timothy W; Caldji, Christian; Fish, Eric; Anisman, Hymie; Szyf, Moshe; Meaney, Michael J

    2006-07-01

    There are profound maternal effects on individual differences in defensive responses and reproductive strategies in species ranging literally from plants to insects to birds. Maternal effects commonly reflect the quality of the environment and are most likely mediated by the quality of the maternal provision (egg, propagule, etc.), which in turn determines growth rates and adult phenotype. In this paper we review data from the rat that suggest comparable forms of maternal effects on defensive responses stress, which are mediated by the effects of variations in maternal behavior on gene expression. Under conditions of environmental adversity maternal effects enhance the capacity for defensive responses in the offspring. In mammals, these effects appear to 'program' emotional, cognitive and endocrine systems towards increased sensitivity to adversity. In environments with an increased level of adversity, such effects can be considered adaptive, enhancing the probability of offspring survival to sexual maturity; the cost is that of an increased risk for multiple forms of pathology in later life.

  6. 2010 Department of Defense (DoD) Chemical and Biological Defense Program (CBDP) Portfolio

    Science.gov (United States)

    2010-03-01

    26 FW OT&E MBU-25/26 FW When integrated with antigravity (anti-G) equipment, the MBU-25 and MBU-26 each provide simultaneous CB protection and anti...Analysis of Materiel Approaches anti-G .............. Antigravity APB .................Acquisition Program Baseline APG

  7. Arbuscular mycorrhizal fungi alter above- and below-ground chemical defense expression differentially among Asclepias species

    Science.gov (United States)

    Vannette, Rachel L.; Hunter, Mark D.; Rasmann, Sergio

    2013-01-01

    Below-ground (BG) symbionts of plants can have substantial influence on plant growth and nutrition. Recent work demonstrates that mycorrhizal fungi can affect plant resistance to herbivory and the performance of above- (AG) and BG herbivores. Although these examples emerge from diverse systems, it is unclear if plant species that express similar defensive traits respond similarly to fungal colonization, but comparative work may inform this question. To examine the effects of arbuscular mycorrhizal fungi (AMF) on the expression of chemical resistance, we inoculated 8 species of Asclepias (milkweed)—which all produce toxic cardenolides—with a community of AMF. We quantified plant biomass, foliar and root cardenolide concentration and composition, and assessed evidence for a growth-defense tradeoff in the presence and absence of AMF. As expected, total foliar and root cardenolide concentration varied among milkweed species. Importantly, the effect of mycorrhizal fungi on total foliar cardenolide concentration also varied among milkweed species, with foliar cardenolides increasing or decreasing, depending on the plant species. We detected a phylogenetic signal to this variation; AMF fungi reduced foliar cardenolide concentrations to a greater extent in the clade including A. curassavica than in the clade including A. syriaca. Moreover, AMF inoculation shifted the composition of cardenolides in AG and BG plant tissues in a species-specific fashion. Mycorrhizal inoculation changed the relative distribution of cardenolides between root and shoot tissue in a species-specific fashion, but did not affect cardenolide diversity or polarity. Finally, a tradeoff between plant growth and defense in non-mycorrhizal plants was mitigated completely by AMF inoculation. Overall, we conclude that the effects of AMF inoculation on the expression of chemical resistance can vary among congeneric plant species, and ameliorate tradeoffs between growth and defense. PMID:24065971

  8. Arbuscular mycorrhizal fungi alter above- and below-ground chemical defense expression differentially among Asclepias species.

    Science.gov (United States)

    Vannette, Rachel L; Hunter, Mark D; Rasmann, Sergio

    2013-01-01

    Below-ground (BG) symbionts of plants can have substantial influence on plant growth and nutrition. Recent work demonstrates that mycorrhizal fungi can affect plant resistance to herbivory and the performance of above- (AG) and BG herbivores. Although these examples emerge from diverse systems, it is unclear if plant species that express similar defensive traits respond similarly to fungal colonization, but comparative work may inform this question. To examine the effects of arbuscular mycorrhizal fungi (AMF) on the expression of chemical resistance, we inoculated 8 species of Asclepias (milkweed)-which all produce toxic cardenolides-with a community of AMF. We quantified plant biomass, foliar and root cardenolide concentration and composition, and assessed evidence for a growth-defense tradeoff in the presence and absence of AMF. As expected, total foliar and root cardenolide concentration varied among milkweed species. Importantly, the effect of mycorrhizal fungi on total foliar cardenolide concentration also varied among milkweed species, with foliar cardenolides increasing or decreasing, depending on the plant species. We detected a phylogenetic signal to this variation; AMF fungi reduced foliar cardenolide concentrations to a greater extent in the clade including A. curassavica than in the clade including A. syriaca. Moreover, AMF inoculation shifted the composition of cardenolides in AG and BG plant tissues in a species-specific fashion. Mycorrhizal inoculation changed the relative distribution of cardenolides between root and shoot tissue in a species-specific fashion, but did not affect cardenolide diversity or polarity. Finally, a tradeoff between plant growth and defense in non-mycorrhizal plants was mitigated completely by AMF inoculation. Overall, we conclude that the effects of AMF inoculation on the expression of chemical resistance can vary among congeneric plant species, and ameliorate tradeoffs between growth and defense.

  9. Arbuscular mycorrhizal fungi alter above- and below-ground chemical defense expression differentially among Asclepias species

    Directory of Open Access Journals (Sweden)

    Rachel L Vannette

    2013-09-01

    Full Text Available Belowground symbionts of plants can have substantial influence on plant growth and nutrition. Recent work demonstrates that mycorrhizal fungi can affect plant resistance to herbivory and the performance of above and belowground herbivores. Although these examples emerge from diverse systems, it is unclear if plant species that express similar defensive traits respond similarly to fungal colonization, but comparative work may inform this question. To examine the effects of arbuscular mycorrhizal fungi (AMF on the expression of chemical resistance, we inoculated 8 species of Asclepias (milkweed--which all produce toxic cardenolides--with a community of AMF. We quantified plant biomass, foliar and root cardenolide concentration and composition, and assessed evidence for a growth-defense tradeoff in the presence and absence of AMF. As expected, total foliar and root cardenolide concentration varied among milkweed species. Importantly, the effect of mycorrhizal fungi on total foliar cardenolide concentration also varied among milkweed species, with foliar cardenolides increasing or decreasing, depending on the plant species. We detected a phylogenetic signal to this variation; AMF fungi reduced foliar cardenolide concentrations to a greater extent in the clade including A. curassavica than in the clade including A. syriaca. Moreover, AMF inoculation shifted the composition of cardenolides in above- and below-ground plant tissues in a species-specific fashion. Mycorrhizal inoculation changed the relative distribution of cardenolides between root and shoot tissue in a species-specific fashion, but did not affect cardenolide diversity or polarity. Finally, a tradeoff between plant growth and defense in non-mycorrhizal plants was mitigated completely by AMF inoculation. Overall, we conclude that the effects of AMF inoculation on the expression of chemical resistance can vary among congeneric plant species, and ameliorate tradeoffs between growth and

  10. Acquisition Program Teamwork and Performance Seen Anew: Exposing the Interplay of Architecture and Behaviors in Complex Defense Programs

    Science.gov (United States)

    2016-04-30

    created an organizational crisis, spurring what is arguably the most successful acquisition reform effort in U.S. defense industry history. Diagnosis and...programs as sociotechnical systems with program performance driven by interpersonal and inter- organizational dynamics as well as technical system...interdependencies are acknowledged in traditional organizational /management literature, they are seldom defined at the level of specificity that is required

  11. Sandia National Laboratories, California Chemical Management Program annual report.

    Energy Technology Data Exchange (ETDEWEB)

    Brynildson, Mark E.

    2012-02-01

    The annual program report provides detailed information about all aspects of the Sandia National Laboratories, California (SNL/CA) Chemical Management Program. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. This program annual report describes the activities undertaken during the calender past year, and activities planned in future years to implement the Chemical Management Program, one of six programs that supports environmental management at SNL/CA. SNL/CA is responsible for tracking chemicals (chemical and biological materials), providing Material Safety Data Sheets (MSDS) and for regulatory compliance reporting according to a variety of chemical regulations. The principal regulations for chemical tracking are the Emergency Planning Community Right-to-Know Act (EPCRA) and the California Right-to-Know regulations. The regulations, the Hazard Communication/Lab Standard of the Occupational Safety and Health Administration (OSHA) are also key to the CM Program. The CM Program is also responsible for supporting chemical safety and information requirements for a variety of Integrated Enabling Services (IMS) programs primarily the Industrial Hygiene, Waste Management, Fire Protection, Air Quality, Emergency Management, Environmental Monitoring and Pollution Prevention programs. The principal program tool is the Chemical Information System (CIS). The system contains two key elements: the MSDS library and the chemical container-tracking database that is readily accessible to all Members of the Sandia Workforce. The primary goal of the CM Program is to ensure safe and effective chemical management at Sandia/CA. This is done by efficiently collecting and managing chemical information for our customers who include Line, regulators, DOE and ES and H programs to ensure compliance with regulations and to streamline customer business processes that require chemical information.

  12. Programmed cell death for defense against anomaly and tumor formation

    International Nuclear Information System (INIS)

    Kondo, Sohei; Norimura, Toshiyuki; Nomura, Taisei

    1995-01-01

    Cell death after exposure to low-level radiation is often considered evidence that radiation is poisonous, however small the dose. Evidence has been accumulating to support the notion that cell death after low-level exposure to radiation results from activation of suicidal genes open-quote programmed cell death close-quote or open-quote apoptosis close-quote - for the health of the whole body. This paper gives experimental evidence that embryos of fruit flies and mouse fetuses have potent defense mechanisms against teratogenic or tumorigenic injury caused by radiation and carcinogens, which function through programmed cell death

  13. Department of Energy Defense Programs Environmental Restoration Program update

    International Nuclear Information System (INIS)

    Lehr, J.C.; Eyman, L.D.; Thompson, W.W. Jr.

    1989-01-01

    Federal facilities are under increasing pressure to remediate inactive hazardous waste sites and associated off-site areas. The Superfund Amendments and Reauthorization Act federal facilities provision requires that the Environmental Protection Agency establish a public docket to list all federal sites contaminated by hazardous wastes or substances and to monitor the progress of investigations and cleanups against an established schedule. In addition, the Resource Conservation and Recovery Act requires that operating permits for hazardous waste treatment, storage, and disposal facilities be issued only upon binding agreements that identify specific schedules for corrective action for all hazardous waste releases that have or are occurring at the facility. Defense Programs (DP) must make remedial actions integral to its mission. Environmental cleanups are given increased emphasis with the new regulations/laws providing the right to private citizens and the states to sue to enforce these statutes and schedule commitments. 1 fig., 2 tabs

  14. Packaging and delivery of chemical weapons: a defensive trojan horse stratagem in chromodorid nudibranchs.

    Science.gov (United States)

    Carbone, Marianna; Gavagnin, Margherita; Haber, Markus; Guo, Yue-Wei; Fontana, Angelo; Manzo, Emiliano; Genta-Jouve, Gregory; Tsoukatou, Maria; Rudman, William B; Cimino, Guido; Ghiselin, Michael T; Mollo, Ernesto

    2013-01-01

    Storage of secondary metabolites with a putative defensive role occurs in the so-called mantle dermal formations (MDFs) that are located in the more exposed parts of the body of most and very likely all members of an entire family of marine mollusks, the chromodorid nudibranchs (Gastropoda: Opisthobranchia). Given that these structures usually lack a duct system, the mechanism for exudation of their contents remains unclear, as does their adaptive significance. One possible explanation could be that they are adapted so as to be preferentially attacked by predators. The nudibranchs might offer packages containing highly repugnant chemicals along with parts of their bodies to the predators, as a defensive variant of the strategic theme of the Trojan horse. We detected, by quantitative (1)H-NMR, extremely high local concentrations of secondary metabolites in the MDFs of six species belonging to five chromodorid genera. The compounds were purified by chromatographic methods and subsequently evaluated for their feeding deterrent properties, obtaining dose-response curves. We found that only distasteful compounds are accumulated in the reservoirs at concentrations that far exceed the values corresponding to maximum deterrent activity in the feeding assays. Other basic evidence, both field and experimental, has been acquired to elucidate the kind of damage that the predators can produce on both the nudibranchs' mantles and the MDFs. As a result of a long evolutionary process that has progressively led to the accumulation of defensive chemical weapons in localized anatomical structures, the extant chromodorid nudibranchs remain in place when molested, retracting respiratory and chemosensory organs, but offering readily accessible parts of their body to predators. When these parts are masticated or wounded by predators, breakage of the MDFs results in the release of distasteful compounds at extremely high concentration in a way that maximizes their repugnant impact.

  15. Packaging and delivery of chemical weapons: a defensive trojan horse stratagem in chromodorid nudibranchs.

    Directory of Open Access Journals (Sweden)

    Marianna Carbone

    Full Text Available Storage of secondary metabolites with a putative defensive role occurs in the so-called mantle dermal formations (MDFs that are located in the more exposed parts of the body of most and very likely all members of an entire family of marine mollusks, the chromodorid nudibranchs (Gastropoda: Opisthobranchia. Given that these structures usually lack a duct system, the mechanism for exudation of their contents remains unclear, as does their adaptive significance. One possible explanation could be that they are adapted so as to be preferentially attacked by predators. The nudibranchs might offer packages containing highly repugnant chemicals along with parts of their bodies to the predators, as a defensive variant of the strategic theme of the Trojan horse.We detected, by quantitative (1H-NMR, extremely high local concentrations of secondary metabolites in the MDFs of six species belonging to five chromodorid genera. The compounds were purified by chromatographic methods and subsequently evaluated for their feeding deterrent properties, obtaining dose-response curves. We found that only distasteful compounds are accumulated in the reservoirs at concentrations that far exceed the values corresponding to maximum deterrent activity in the feeding assays. Other basic evidence, both field and experimental, has been acquired to elucidate the kind of damage that the predators can produce on both the nudibranchs' mantles and the MDFs.As a result of a long evolutionary process that has progressively led to the accumulation of defensive chemical weapons in localized anatomical structures, the extant chromodorid nudibranchs remain in place when molested, retracting respiratory and chemosensory organs, but offering readily accessible parts of their body to predators. When these parts are masticated or wounded by predators, breakage of the MDFs results in the release of distasteful compounds at extremely high concentration in a way that maximizes their repugnant

  16. Acidity enhances the effectiveness of active chemical defensive secretions of sea hares, Aplysia californica, against spiny lobsters, Panulirus interruptus.

    Science.gov (United States)

    Shabani, Shkelzen; Yaldiz, Seymanur; Vu, Luan; Derby, Charles D

    2007-12-01

    Sea hares such as Aplysia californica, gastropod molluscs lacking a protective shell, can release a purple cloud of chemicals when vigorously attacked by predators. This active chemical defense is composed of two glandular secretions, ink and opaline, both of which contain an array of compounds. This secretion defends sea hares against predators such as California spiny lobsters Panulirus interruptus via multiple mechanisms, one of which is phagomimicry, in which secretions containing feeding chemicals attract and distract predators toward the secretion and away from the sea hare. We show here that ink and opaline are highly acidic, both having a pH of approximately 5. We examined if the acidity of ink and opaline affects their phagomimetic properties. We tested behavioral and electrophysiological responses of chemoreceptor neurons in the olfactory and gustatory organs of P. interruptus, to ink and opaline of A. californica within their natural range of pH values, from approximately 5 to 8. Both behavioral and electrophysiological responses to ink and opaline were enhanced at low pH, and low pH alone accounted for most of this effect. Our data suggest that acidity enhances the phagomimetic chemical defense of sea hares.

  17. Defense High-Level Waste Leaching Mechanisms Program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Mendel, J.E. (compiler)

    1984-08-01

    The Defense High-Level Waste Leaching Mechanisms Program brought six major US laboratories together for three years of cooperative research. The participants reached a consensus that solubility of the leached glass species, particularly solubility in the altered surface layer, is the dominant factor controlling the leaching behavior of defense waste glass in a system in which the flow of leachant is constrained, as it will be in a deep geologic repository. Also, once the surface of waste glass is contacted by ground water, the kinetics of establishing solubility control are relatively rapid. The concentrations of leached species reach saturation, or steady-state concentrations, within a few months to a year at 70 to 90/sup 0/C. Thus, reaction kinetics, which were the main subject of earlier leaching mechanisms studies, are now shown to assume much less importance. The dominance of solubility means that the leach rate is, in fact, directly proportional to ground water flow rate. Doubling the flow rate doubles the effective leach rate. This relationship is expected to obtain in most, if not all, repository situations.

  18. Defense High-Level Waste Leaching Mechanisms Program. Final report

    International Nuclear Information System (INIS)

    Mendel, J.E.

    1984-08-01

    The Defense High-Level Waste Leaching Mechanisms Program brought six major US laboratories together for three years of cooperative research. The participants reached a consensus that solubility of the leached glass species, particularly solubility in the altered surface layer, is the dominant factor controlling the leaching behavior of defense waste glass in a system in which the flow of leachant is constrained, as it will be in a deep geologic repository. Also, once the surface of waste glass is contacted by ground water, the kinetics of establishing solubility control are relatively rapid. The concentrations of leached species reach saturation, or steady-state concentrations, within a few months to a year at 70 to 90 0 C. Thus, reaction kinetics, which were the main subject of earlier leaching mechanisms studies, are now shown to assume much less importance. The dominance of solubility means that the leach rate is, in fact, directly proportional to ground water flow rate. Doubling the flow rate doubles the effective leach rate. This relationship is expected to obtain in most, if not all, repository situations

  19. Plant antiherbivore defenses in Fabaceae species of the Chaco.

    Science.gov (United States)

    Lima, T E; Sartori, A L B; Rodrigues, M L M

    2017-01-01

    The establishment and maintenance of plant species in the Chaco, one of the widest continuous areas of forests in the South American with sharp climatic variations, are possibly related to biological features favoring plants with particular defenses. This study assesses the physical and chemical defenses mechanisms against herbivores of vegetative and reproductive organs. Its analyses of 12 species of Fabaceae (Leguminosae) collected in remnants of Brazilian Chaco shows that 75% present structural defense characters and 50% have chemical defense - defense proteins in their seeds, like protease inhibitors and lectins. Physical defenses occur mainly on branches (78% of the species), leaves (67%), and reproductive organs (56%). The most common physical characters are trichomes and thorns, whose color represents a cryptic character since it does not contrast with the other plant structures. Defense proteins occur in different concentrations and molecular weight classes in the seeds of most species. Protease inhibitors are reported for the first time in seeds of: Albizia niopoides, Anadenanthera colubrina, Mimosa glutinosa, Prosopis rubriflora, and Poincianella pluviosa. The occurrence of physical and chemical defenses in members of Fabaceae indicate no associations between defense characters in these plant species of the Chaco.

  20. Review of the President's Fiscal Year 2009 Budget Request for the Defense Health Program's Private Sector Care Budget Activity Group

    National Research Council Canada - National Science Library

    Fantone, Denise M; Pickup, Sharon

    2008-01-01

    The Conference Report accompanying the Fiscal Year 2008 Department of Defense Appropriations bill directed us to review the President's fiscal year 2009 budget request for the Defense Health Program's...

  1. Determination of the capabilities of a detachment for neutralizing chemical attack effects in the brigade defense zone

    Directory of Open Access Journals (Sweden)

    Dejan R. Inđić

    2012-04-01

    Full Text Available This paper presents one possible way of deploying detachments for neutralizing the effects of chemical attacks in a brigade defense zone. The detachment composition is provisional and depends on the assessment of whether the enemy in the incoming combat will use weapons of mass destruction. A detachment consists of several organizational units: medical care forces, chemical reconnaissance forces, forces for the establishment of combat efficiency and chemical decontamination forces. The capabilities of the mentioned forces depend on their size, equipment, training level, extent of effects and combat conditions. The paper indicates a potential to overcome the gap in the provisions after disbanding the Army Corps.

  2. Defense Programs and Budget Risk

    National Research Council Canada - National Science Library

    Troutman, Mark D

    2006-01-01

    .... Therefore the Defense Department has set before itself a requirement to modernize a large conventional force structure engaged in ongoing combat operations while simultaneously developing deeper...

  3. Inducible defenses against herbivory and fouling in seaweeds

    Science.gov (United States)

    Pereira, Renato Crespo; Costa, Erica da Silva; Sudatti, Daniela Bueno; da Gama, Bernardo Antonio Perez

    2017-04-01

    Secondary metabolites play an important ecological role as a defense mechanism in seaweeds. Chemical defenses are well known to change in response to herbivory, but other driving factors, either biotic or abiotic, are often neglected. Epibiosis may not only reduce seaweed fitness, but also increase attractiveness to consumers, and thus defense production should also be triggered by epibionts. In this study, three Southwestern Atlantic seaweeds, Gracilaria cearensis, Pterocladiella capillacea (Rhodophyceae) and Codium decorticatum (Chlorophyceae) were investigated in laboratory bioassays designed to test whether the action of herbivory or simulated epibiosis influences chemical defenses. Crossed induction experiments were also performed in order to assess whether herbivore induction influences antifouling chemical defense, as well as whether epibiont induction would affect defense against herbivores. The effect of laboratory conditions on seaweeds in the absence of field stimuli was also investigated by comparing consumption of artificial food with extracts from acclimatized and non-acclimatized seaweeds (i.e., natural defense levels). Only the green seaweed C. decorticatum exhibited inducible antifouling defenses triggered by simulated epibiosis, but not by herbivores. In the other seaweeds there was no induction either by herbivory or simulated epibiosis. Acclimatization did not affect C. decorticatum defenses. However, non-acclimatized G. cearensis artificial foods were preferred over acclimatized ones, while extracts from acclimatized P. capillacea increased herbivore consumption, highlighting the need to acclimatize seaweeds before the main induction experiments. This is the first report of inducible defenses due to simulated fouling in seaweeds.

  4. Implementation and Sustainability of the Russian Federation Ministry of Defense Nuclear Personnel Reliability Program

    International Nuclear Information System (INIS)

    Lata, Vasiliy; Coates, Cameron W.

    2010-01-01

    Through a cooperative effort between the US Department of Energy and the Russian Federation (RF) Ministry of Defense (MOD) a Personnel Reliability Program (PRP) for the nuclear handlers within the RF MOD is at the stage of implementation. Sustaining the program is of major significance for long term success. This paper will discuss the elements of the RF PRP and the equipment needs for implementation. Program requirements, documentation needs, training, and assurances of appropriate equipment use will be addressed.

  5. Sandia National Laboratories: National Security Missions: Defense Systems

    Science.gov (United States)

    ; Technology Defense Systems & Assessments About Defense Systems & Assessments Program Areas Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios ; Culture Work-Life Balance Special Programs Nuclear Weapons Defense Systems Global Security Energy Facebook

  6. Defense transuranic waste program strategy document

    International Nuclear Information System (INIS)

    1982-07-01

    This document summarizes the strategy for managing transuranic (TRU) wastes generated in defense and research activities regulated by the US Department of Energy. It supercedes a document issued in July 1980. In addition to showing how current strategies of the Defense Transuranic Waste Program (DTWP) are consistent with the national objective of isolating radioactive wastes from the biosphere, this document includes information about the activities of the Transuranic Lead Organization (TLO). To explain how the DTWP strategy is implemented, this document also discusses how the TLO coordinates and integrates the six separate elements of the DTWP: (1) Waste Generation Site Activities, (2) Storage Site Activities, (3) Burial Site Activities, (4) Technology Development, (5) Transportation Development, and (6) Permanent Disposal. Storage practices for TRU wastes do not pose short-term hazards to public health and safety or to the environment. Isolation of TRU wastes in a deep-mined geologic repository is considered the most promising of the waste disposal alternatives available. This assessment is supported by the DOE Record of Decision to proceed with research and development work at the Waste Isolation Pilot Plant (WIPP) in southeastern New Mexico - a deep-mined geologic research and development project. In support of the WIPP research project and the permanent disposal of TRU waste, the DTWP strategy for the near term will concentrate on completion of procedures and the design and construction of all facilities necessary to certify newly-generated (NG) and stored TRU wastes for emplacement in the WIPP. In addition, the strategy involves evaluating alternatives for disposing of some transuranic wastes by methods which may allow for on-site disposal of these wastes and yet preserve adequate margins of safety to protect public health and the environment

  7. Program Solicitation 2001.2. Closing Date: 15 August 2001. FY 2001 Small Business Innovation Research (SBIR) Program

    National Research Council Canada - National Science Library

    2001-01-01

    ...), and Chemical and Biological Defense (CBD) hereafter referred to as DoD Components, invite small business firms to submit proposals under this solicitation for the Small Business Innovation Research (SBIR) program...

  8. 76 FR 71467 - Defense Federal Acquisition Regulation Supplement; Extension of Department of Defense Mentor...

    Science.gov (United States)

    2011-11-18

    ... Defense Mentor-Prot[eacute]g[eacute] Pilot Program (DFARS Case 2011-D050) AGENCY: Defense Acquisition... applications under the DoD Mentor-Prot[eacute]g[eacute] Pilot Program for new mentor-prot[eacute]g[eacute] agreements and the date mentors may incur costs and/or receive credit towards fulfilling their small business...

  9. Risk assessment and ranking methodologies for hazardous chemical defense waste: a state-of-the-art review and evaluation. Task 1 report

    International Nuclear Information System (INIS)

    Chu, M.S.Y.; Rodricks, J.V.; St Hilaire, C.; Bras, R.L.

    1986-06-01

    This report summarizes the work performed under Task 1 of the Risk Assessment Evaluation Task under the Hazardous Chemical Defense Waste Management Program of the Department of Energy (DOE). The objective of Task 1 was to identify, review, and evaluate the state-of-the-art tools and techniques available for ranking and evaluating disposal facilities. These tools were evaluated for their applicability to DOE's mixed hazardous chemical and radioactive waste sites. Various ranking methodologies were reviewed and three were evaluated in detail. Areas that were found to be deficient in each ranking methodology were presented in the report. Recommendations were given for the development of an improved ranking methodology for use on DOE's sites. A literature review was then performed on the various components of a risk assessment methodology. They include source term evaluation, geosphere transport models, exposure pathways models, dose effects models, and sensitivity/uncertainty techniques. A number of recommendations have been made in the report based on the review and evaluation for the development of a comprehensive risk assessment methodology in evaluating mixed waste disposal sites

  10. Localization of Defensive Chemicals in Two Congeneric Butterflies (Euphydryas, Nymphalidae).

    Science.gov (United States)

    Mason, Peri A; Deane Bowers, M

    2017-05-01

    Many insect species sequester compounds acquired from their host plants for defense against natural enemies. The distribution of these compounds is likely to affect both their efficacy as defenses, and their costs. In this study we examined the distribution of sequestered iridoid glycosides (IGs) in two congeneric species of nymphalid butterfly, Euphydryas anicia and E. phaeton, and found that the pattern of localization of IGs differed between the two species. Although IG concentrations were quite high in the heads of both species, the relative concentrations in wings and abdomens differed substantially. Euphydryas anicia had relatively high IG concentrations in their abdomens and low IG concentrations in their wings, whereas the reverse was true in E. phaeton. We interpret these results in light of two current hypotheses regarding where sequestered chemicals should be localized: that they should be found in wings, which would allow non-lethal sampling by predators; and that their distribution is constrained by the distribution of tissue types to which sequestered compounds bind. We also offer the third hypothesis, that costs of storage may differ among body parts, and that the localization of compounds may reflect a cost-reduction strategy. Results from E. phaeton were consistent with all three of these non-mutually exclusive hypotheses, whereas results from E. anicia were only consistent with the notion that tissue bias among body parts plays a role in IG distribution. The finding that these two congeneric butterflies exhibit different patterns of IG localization suggests that they have been shaped by different selection regimes.

  11. Status of defense radioactive waste disposal activities

    International Nuclear Information System (INIS)

    Wade, T.W.

    1988-01-01

    The Office of Defense Programs, U.S. Department of Energy, is responsible for the production of nuclear weapons and materials for national defense. As a byproduct to their activities, nuclear production facilities have generated, and will continue to generate, certain radioactive, hazardous, or mixed wastes that must be managed and disposed of in a safe and cost-effective manner. Compliance with all applicable Federal and State regulations is required. This paper describes the principal elements that comprise Defense Programs' approach to waste management and disposal. The status of high-level, transuranic, and low-level radioactive waste disposal is set forth. Defense Programs' activities in connection with the environmental restoration of inactive facilities and with the safe transport of waste materials are summarized. Finally, the principal challenges to realizing the goals set for the defense waste program are discussed in terms of regulatory, public acceptance, technical, and budget issues

  12. Review of the Fiscal Year 2014 (FY14) Defense Environmental International Cooperation (DEIC) Program

    Science.gov (United States)

    2015-05-01

    advanced by the U.S. team, and embraced by the participants, was to retrain approximately 20 percent of the military force to address ecologically ...the lead for the State Partnership Program with Chile . Discussions focused on environmental programs in both countries, as well as working group...sessions to develop collaborative plans for the next three to five years under the U.S.- Chile Defense Consultative Commission (DCC) in the areas of

  13. 77 FR 11367 - Defense Federal Acquisition Regulation Supplement; Extension of the Department of Defense Mentor...

    Science.gov (United States)

    2012-02-24

    ... Defense Mentor-Prot[eacute]g[eacute] Pilot Program (DFARS Case 2012-D024) AGENCY: Defense Acquisition... applications under the DoD Mentor-Prot[eacute]g[eacute] Pilot Program for new mentor-prot[eacute]g[eacute] agreements and the date mentors may incur costs and/or receive credit towards fulfilling their small business...

  14. Early Warning: Brought to you by the DoD Chem-Bio Defense Program

    Science.gov (United States)

    Security Robots Lasers RSS Feed Early Warning: Brought to you by the DoD Chem-Bio Defense Program help warfighters prevent, protect against, respond to or recover from chem-bio threats and effects . Hassell said he and his team don't monitor the world for chem-bio threats, they develop the tools that

  15. Shifts in Plant Chemical Defenses of Chile Pepper (Capsicum annuum L. Due to Domestication in Mesoamerica

    Directory of Open Access Journals (Sweden)

    Jose de Jesus Luna-Ruiz

    2018-04-01

    Full Text Available We propose that comparisons of wild and domesticated Capsicum species can serve as a model system for elucidating how crop domestication influences biotic and abiotic interactions mediated by plant chemical defenses. Perhaps no set of secondary metabolites (SMs used for plant defenses and human health have been better studied in the wild and in milpa agro-habitats than those found in Capsicum species. However, very few scientific studies on SM variation have been conducted in both the domesticated landraces of chile peppers and in their wild relatives in the Neotropics. In particular, capsaicinoids in Capsicum fruits and on their seeds differ in the specificity of their ecological effects from broad-spectrum toxins in other members of the Solanaceae. They do so in a manner that mediates specific ecological interactions with a variety of sympatric Neotropical vertebrates, invertebrates, nurse plants and microbes. Specifically, capsaicin is a secondary metabolite (SM in the placental tissues of the chile fruit that mediates interactions with seed dispersers such as birds, and with seed predators, ranging from fungi to insects and rodents. As with other Solanaceae, a wide range of SMs in Capsicum spp. function to ecologically mediate the effects of a variety of biotic and abiotic stresses on wild chile peppers in certain tropical and subtropical habitats. However, species in the genus Capsicum are the only ones found within any solanaceous genus that utilize capsaicinoids as their primary means of chemical defense. We demonstrate how exploring in tandem the evolutionary ecology and the ethnobotany of human-chile interactions can generate and test novel hypotheses with regard to how the domestication process shifts plant chemical defense strategies in a variety of tropical crops. To do so, we draw upon recent advances regarding the chemical ecology of a number of wild Capsicum species found in the Neotropics. We articulate three hypotheses regarding

  16. Transportation System Risk Assessment on DOE Defense Program shipments

    International Nuclear Information System (INIS)

    Brumburgh, G.P.; Kimura, C.Y.; Alesso, H.P.; Prassinos, P.G.

    1992-01-01

    Substantial effort has been expended concerning the level of safety provided to persons, property, and the environment from the hazards associated with transporting radioactive material. This work provided an impetus for the Department of Energy to investigate the use of probabilistic risk assessment techniques to supplement the deterministic approach to transportation safety. The DOE recently decided to incorporate the methodologies associated with PRAs in the process for authorizing the transportation of nuclear components, special assemblies, and radioactive materials affiliated with the DOE Defense Program. Accordingly, the LLNL, sponsored by the DOE/AL, is tasked with developing a safety guide series to provide guidance to preparers performing a transportation system risk assessment

  17. Defense Waste Processing Facility Nitric- Glycolic Flowsheet Chemical Process Cell Chemistry: Part 2

    Energy Technology Data Exchange (ETDEWEB)

    Zamecnik, J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Edwards, T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-06-06

    The conversions of nitrite to nitrate, the destruction of glycolate, and the conversion of glycolate to formate and oxalate were modeled for the Nitric-Glycolic flowsheet using data from Chemical Process Cell (CPC) simulant runs conducted by Savannah River National Laboratory (SRNL) from 2011 to 2016. The goal of this work was to develop empirical correlation models to predict these values from measureable variables from the chemical process so that these quantities could be predicted a-priori from the sludge or simulant composition and measurable processing variables. The need for these predictions arises from the need to predict the REDuction/OXidation (REDOX) state of the glass from the Defense Waste Processing Facility (DWPF) melter. This report summarizes the work on these correlations based on the aforementioned data. Previous work on these correlations was documented in a technical report covering data from 2011-2015. This current report supersedes this previous report. Further refinement of the models as additional data are collected is recommended.

  18. Feeding on Host Plants with Different Concentrations and Structures of Pyrrolizidine Alkaloids Impacts the Chemical-Defense Effectiveness of a Specialist Herbivore.

    Science.gov (United States)

    Martins, Carlos H Z; Cunha, Beatriz P; Solferini, Vera N; Trigo, José R

    2015-01-01

    Sequestration of chemical defenses from host plants is a strategy widely used by herbivorous insects to avoid predation. Larvae of the arctiine moth Utetheisa ornatrix feeding on unripe seeds and leaves of many species of Crotalaria (Leguminosae) sequester N-oxides of pyrrolizidine alkaloids (PAs) from these host plants, and transfer them to adults through the pupal stage. PAs confer protection against predation on all life stages of U. ornatrix. As U. ornatrix also uses other Crotalaria species as host plants, we evaluated whether the PA chemical defense against predation is independent of host plant use. We fed larvae from hatching to pupation with either leaves or seeds of one of eight Crotalaria species (C. incana, C. juncea, C. micans, C. ochroleuca, C. pallida, C. paulina, C. spectabilis, and C. vitellina), and tested if adults were preyed upon or released by the orb-weaving spider Nephila clavipes. We found that the protection against the spider was more effective in adults whose larvae fed on seeds, which had a higher PA concentration than leaves. The exceptions were adults from larvae fed on C. paulina, C. spectabilis and C. vitellina leaves, which showed high PA concentrations. With respect to the PA profile, we describe for the first time insect-PAs in U. ornatrix. These PAs, biosynthesized from the necine base retronecine of plant origin, or monocrotaline- and senecionine-type PAs sequestered from host plants, were equally active in moth chemical defense, in a dose-dependent manner. These results are also partially explained by host plant phylogeny, since PAs of the host plants do have a phylogenetic signal (clades with high and low PA concentrations in leaves) which is reflected in the adult defense.

  19. Feeding on Host Plants with Different Concentrations and Structures of Pyrrolizidine Alkaloids Impacts the Chemical-Defense Effectiveness of a Specialist Herbivore.

    Directory of Open Access Journals (Sweden)

    Carlos H Z Martins

    Full Text Available Sequestration of chemical defenses from host plants is a strategy widely used by herbivorous insects to avoid predation. Larvae of the arctiine moth Utetheisa ornatrix feeding on unripe seeds and leaves of many species of Crotalaria (Leguminosae sequester N-oxides of pyrrolizidine alkaloids (PAs from these host plants, and transfer them to adults through the pupal stage. PAs confer protection against predation on all life stages of U. ornatrix. As U. ornatrix also uses other Crotalaria species as host plants, we evaluated whether the PA chemical defense against predation is independent of host plant use. We fed larvae from hatching to pupation with either leaves or seeds of one of eight Crotalaria species (C. incana, C. juncea, C. micans, C. ochroleuca, C. pallida, C. paulina, C. spectabilis, and C. vitellina, and tested if adults were preyed upon or released by the orb-weaving spider Nephila clavipes. We found that the protection against the spider was more effective in adults whose larvae fed on seeds, which had a higher PA concentration than leaves. The exceptions were adults from larvae fed on C. paulina, C. spectabilis and C. vitellina leaves, which showed high PA concentrations. With respect to the PA profile, we describe for the first time insect-PAs in U. ornatrix. These PAs, biosynthesized from the necine base retronecine of plant origin, or monocrotaline- and senecionine-type PAs sequestered from host plants, were equally active in moth chemical defense, in a dose-dependent manner. These results are also partially explained by host plant phylogeny, since PAs of the host plants do have a phylogenetic signal (clades with high and low PA concentrations in leaves which is reflected in the adult defense.

  20. Reflecting on 20+ Years of “Executive Program in Defense Decision Making” Curriculum

    OpenAIRE

    2017-01-01

    CCMR News Article CCMR hosted a version of its biannual “Executive Program in Defense Decision Making” offering for 21 international military and civilian participants, from November 6-17, 2017. Often described as CCMR’s “flagship” course, this curriculum has been offered at the Naval Postgraduate School (NPS) in Monterey, California for over 20 years.

  1. Study of flood defense structural measures priorities using Compromise Programming technique

    Science.gov (United States)

    Lim, D.; Jeong, S.

    2017-12-01

    Recent climate change of global warming has led to the frequent occurrence of heavy regional rainfalls. As such, inundation vulnerability increases in urban areas with high population density due to the low runoff carrying capacity. This study selects a sample area (Janghang-eup, the Republic of Korea), which is one of the most vulnerable areas to flooding, analyzing the urban flood runoff model (XP-SWMM) and using the MCDM (Multi-Criteria Decision Making) technique to establish flood protection structural measures. To this end, we compare the alternatives and choose the optimal flood defense measure: our model is utilized with three flood prevention structural measures; (i) drainage pipe construction; (ii) water detention; and (iii) flood pumping station. Dividing the target area into three small basins, we propose flood evaluations for an inundation decrease by studying the flooded area, the maximum inundation depth, the damaged residential area, and the construction cost. In addition, Compromise Programming determines the priority of the alternatives. As a consequent, this study suggests flood pumping station for Zone 1 and drainage pipe construction for Zone 2 and Zone 3, respectively, as the optimal flood defense alternative. Keywords : MCDM; Compromise Programming; Urban Flood Prevention; This research was supported by a grant [MPSS-DP-2013-62] through the Disaster and Safety Management Institute funded by Ministry of Public Safety and Security of Korean government.

  2. Knockout of Arabidopsis accelerated-cell-death11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense

    DEFF Research Database (Denmark)

    Brodersen, Peter; Petersen, Morten; Pike, Helen M

    2002-01-01

    by avirulent pathogens. Global transcriptional changes during programmed cell death (PCD) and defense activation in acd11 were monitored by cDNA microarray hybridization. The PCD and defense pathways activated in acd11 are salicylic acid (SA) dependent, but do not require intact jasmonic acid or ethylene...

  3. Major national human biomonitoring programs in chemical exposure assessment

    Directory of Open Access Journals (Sweden)

    Judy Choi

    2015-07-01

    Full Text Available Human biomonitoring (HBM programs have been established in several countries around the world in order to monitor the levels of chemical exposures in the general population and qualify health risk assessment of national and international interest. Study design, population, sample collection, and chemical analysis must be considered when comparing and interpreting the results. In this review, the objectives and brief descriptions of the major national HBM programs in North America, Europe, and Asia are provided. Similarities and differences observed from a comparative analysis among these programs, including the stratification of data according to age, sex, socioeconomic background, etc. as well as the identification of chemical exposure associated with food intake, are discussed. Overall, although there are some discrepancies in the study designs among the reviewed national HBM programs, results from the programs can provide useful information such as chemical levels found within the general population of a country that can be compared. Furthermore, the results can be used by regulatory authorities or the government to enforce legislations in order to reduce the exposure of chemicals into the human body.

  4. Superhydrophobic powder additives to enhance chemical agent resistant coating systems for military equipment for the U.S. Marine Corps (USMC) Corrosion Prevention and Control (CPAC) Program

    Energy Technology Data Exchange (ETDEWEB)

    Pawel, Steven J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Armstrong, Beth L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Haynes, James A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-07-01

    The primary goal of the CPAC program at ORNL was to explore the feasibility of introducing various silica-based superhydrophobic (SH) powder additives as a way to improve the corrosion resistance of US Department of Defense (DOD) military-grade chemical agent resistant coating (CARC) systems. ORNL had previously developed and patented several SH technologies of interest to the USMC, and one of the objectives of this program was to identify methods to incorporate these technologies into the USMC’s corrosion-resistance strategy. This report discusses findings of the CPAC and their application.

  5. SELECTION OF CHEMICAL TREATMENT PROGRAM FOR OILY WASTEWATER

    Directory of Open Access Journals (Sweden)

    Miguel Díaz

    2017-04-01

    Full Text Available When selecting a chemical treatment program for wastewater to achieve an effective flocculation and coagulation is crucial to understand how individual colloids interact. The coagulation process requires a rapid mixing while flocculation process needs a slow mixing. The behavior of colloids in water is strongly influenced by the electrokinetic charge, where each colloidal particle carries its own charge, which in its nature is usually negative. Polymers, which are long chains of high molecular weight and high charge, when added to water begin to form longer chains, allowing removing numerous particles of suspended matter. A study of physico-chemical treatment by addition of coagulant and flocculant was carried out in order to determine a chemical program for oily wastewater coming from the gravity separation process in a crude oil refinery. The tests were carried out in a Jar Test equipment, where commercial products: aluminum polychloride (PAC, aluminum sulfate and Sintec D50 were evaluated with five different flocculants. The selected chemical program was evaluated with fluids at three temperatures to know its sensitivity to this parameter and the mixing energy in the coagulation and flocculation. The chemical program and operational characteristics for physico-chemical treatment with PAC were determined, obtaining a removal of more than 93% for suspended matter and 96% for total hydrocarbons for the selected coagulant / flocculant combination.

  6. 2007 Joint Chemical Biological, Radiological and Nuclear (CBRN) Conference and Exhibition - Combating Weapons of Mass Destruction

    Science.gov (United States)

    2007-06-27

    Selected CB Defense Systems SHAPESENSE Joint Warning and Reporting Network JSLIST CB Protected Shelter Joint Vaccine Acquisition Program Joint Effects...military can operate in any environment, unconstrained by chemical or biological weapons. 21 SHIELD SUSTAIN Selected CB Defense Systems SHAPESENSE Joint...28070625_JCBRN_Conference_Reeves UNCLASSIFIED Decontamination Vision Strippable Barriers Self-Decontaminating Fabrics/Coatings Reduce Logistics Burden

  7. Defense programs beryllium good practice guide

    Energy Technology Data Exchange (ETDEWEB)

    Herr, M.

    1997-07-01

    Within the DOE, it has recently become apparent that some contractor employees who have worked (or are currently working) with and around beryllium have developed chronic beryllium disease (CBD), an occupational granulomatous lung disorder. Respiratory exposure to aerosolized beryllium, in susceptible individuals, causes an immunological reaction that can result in granulomatous scarring of the lung parenchyma, shortness of breath, cough, fatigue, weight loss, and, ultimately, respiratory failure. Beryllium disease was originally identified in the 1940s, largely in the fluorescent light industry. In 1950, the Atomic Energy Commission (AEC) introduced strict exposure standards that generally curtailed both the acute and chronic forms of the disease. Beginning in 1984, with the identification of a CBD case in a DOE contractor worker, there was increased scrutiny of both industrial hygiene practices and individuals in this workforce. To date, over 100 additional cases of beryllium-specific sensitization and/or CBD have been identified. Thus, a disease previously thought to be largely eliminated by the adoption of permissible exposure standards 45 years ago is still a health risk in certain workforces. This good practice guide forms the basis of an acceptable program for controlling workplace exposure to beryllium. It provides (1) Guidance for minimizing worker exposure to beryllium in Defense Programs facilities during all phases of beryllium-related work, including the decontamination and decommissioning (D&D) of facilities. (2) Recommended controls to be applied to the handling of metallic beryllium and beryllium alloys, beryllium oxide, and other beryllium compounds. (3) Recommendations for medical monitoring and surveillance of workers exposed (or potentially exposed) to beryllium, based on the best current understanding of beryllium disease and medical diagnostic tests available. (4) Site-specific safety procedures for all processes of beryllium that is likely to

  8. National toxicology program chemical nomination and selection process

    Energy Technology Data Exchange (ETDEWEB)

    Selkirk, J.K. [National Institute of Environmental Health Sciences, Research Triangle Park, NC (United States)

    1990-12-31

    The National Toxicology Program (NTP) was organized to support national public health programs by initiating research designed to understand the physiological, metabolic, and genetic basis for chemical toxicity. The primary mandated responsibilities of NTP were in vivo and vitro toxicity testing of potentially hazardous chemicals; broadening the spectrum of toxicological information on known hazardous chemicals; validating current toxicological assay systems as well as developing new and innovative toxicity testing technology; and rapidly communicating test results to government agencies with regulatory responsibilities and to the medical and scientific communities. 2 figs.

  9. Interspecific variation in persistence of buried weed seeds follows trade-offs among physiological, chemical, and physical seed defenses.

    Science.gov (United States)

    Davis, Adam S; Fu, Xianhui; Schutte, Brian J; Berhow, Mark A; Dalling, James W

    2016-10-01

    Soil seedbanks drive infestations of annual weeds, yet weed management focuses largely on seedling mortality. As weed seedbanks increasingly become reservoirs of herbicide resistance, species-specific seedbank management approaches will be essential to weed control. However, the development of seedbank management strategies can only develop from an understanding of how seed traits affect persistence.We quantified interspecific trade-offs among physiological, chemical, and physical traits of weed seeds and their persistence in the soil seedbank in a common garden study. Seeds of 11 annual weed species were buried in Savoy, IL, from 2007 through 2012. Seedling recruitment was measured weekly and seed viability measured annually. Seed physiological (dormancy), chemical (phenolic compound diversity and concentration; invertebrate toxicity), and physical traits (seed coat mass, thickness, and rupture resistance) were measured.Seed half-life in the soil ( t 0.5 ) showed strong interspecific variation ( F 10,30  = 15, p  central role of seed dormancy in controlling seed persistence.A quantitative comparison between our results and other published work indicated that weed seed dormancy and seedbank persistence are linked across diverse environments and agroecosystems. Moreover, among seedbank-forming early successional plant species, relative investment in chemical and physical seed defense varies with seedbank persistence. Synthesis and applications . Strong covariance among weed seed traits and persistence in the soil seedbank indicates potential for seedbank management practices tailored to specific weed species. In particular, species with high t 0.5 values tend to invest less in chemical defenses. This makes them highly vulnerable to physical harvest weed seed control strategies, with small amounts of damage resulting in their full decay.

  10. Chemical and mechanical defenses vary among maternal lines and leaf ages in Verbascum thapsus L. (Scrophulariaceae and reduce palatability to a generalist insect.

    Directory of Open Access Journals (Sweden)

    Christina Alba

    Full Text Available Intra-specific variation in host-plant quality affects herbivore foraging decisions and, in turn, herbivore foraging decisions mediate plant fitness. In particular, variation in defenses against herbivores, both among and within plants, shapes herbivore behavior. If variation in defenses is genetically based, it can respond to natural selection by herbivores. We quantified intra-specific variation in iridoid glycosides, trichome length, and leaf strength in common mullein (Verbascum thapsus L, Scrophulariaceae among maternal lines within a population and among leaves within plants, and related this variation to feeding preferences of a generalist herbivore, Trichopulsia ni Hübner. We found significant variation in all three defenses among maternal lines, with T. ni preferring plants with lower investment in chemical, but not mechanical, defense. Within plants, old leaves had lower levels of all defenses than young leaves, and were strongly preferred by T. ni. Caterpillars also preferred leaves with trichomes removed to leaves with trichomes intact. Differences among maternal lines indicate that phenotypic variation in defenses likely has a genetic basis. Furthermore, these results reveal that the feeding behaviors of T. ni map onto variation in plant defense in a predictable way. This work highlights the importance of variation in host-plant quality in driving interactions between plants and their herbivores.

  11. Chemical and mechanical defenses vary among maternal lines and leaf ages in Verbascum thapsus L. (Scrophulariaceae) and reduce palatability to a generalist insect.

    Science.gov (United States)

    Alba, Christina; Bowers, M Deane; Blumenthal, Dana; Hufbauer, Ruth A

    2014-01-01

    Intra-specific variation in host-plant quality affects herbivore foraging decisions and, in turn, herbivore foraging decisions mediate plant fitness. In particular, variation in defenses against herbivores, both among and within plants, shapes herbivore behavior. If variation in defenses is genetically based, it can respond to natural selection by herbivores. We quantified intra-specific variation in iridoid glycosides, trichome length, and leaf strength in common mullein (Verbascum thapsus L, Scrophulariaceae) among maternal lines within a population and among leaves within plants, and related this variation to feeding preferences of a generalist herbivore, Trichopulsia ni Hübner. We found significant variation in all three defenses among maternal lines, with T. ni preferring plants with lower investment in chemical, but not mechanical, defense. Within plants, old leaves had lower levels of all defenses than young leaves, and were strongly preferred by T. ni. Caterpillars also preferred leaves with trichomes removed to leaves with trichomes intact. Differences among maternal lines indicate that phenotypic variation in defenses likely has a genetic basis. Furthermore, these results reveal that the feeding behaviors of T. ni map onto variation in plant defense in a predictable way. This work highlights the importance of variation in host-plant quality in driving interactions between plants and their herbivores.

  12. Soviet civil defense is inadequate and meaningless

    International Nuclear Information System (INIS)

    Kaplan, F.M.

    1985-01-01

    In this paper, the author argues that Soviet civil defense plans exist primarily on paper and are used to pacify the Soviet people, not as plans to survive and prevail in a nuclear confrontation with the U.S. The author describes how the Soviet people have little faith in the civil defense programs. They don't believe they can survive an attack. Furthermore, he says the Soviets have never staged an evacuation exercise in any major city nor, even in smaller towns, has an entire community been evacuated. The author says there are numerous problems with the shelter programs as well. Very few existing shelters have any food stocks, only a few more have any water. There is little evidence that Soviet leaders have planned their economy with civil defense in mind. Nor - given the blatant inadequacies of Soviet civil defense programs, the marked vulnerabilities of the Soviet economy, and the intrinsic limitation and uncertainties about civil defense generally - is there much basis for claiming that Soviet leaders, even in desperate straits, would risk war with the United States while counting on civil defense measures to limit the damage wreaked on the Soviet Union

  13. Defense Dollars and Sense: A Common Cause Guide to the Defense Budget Process.

    Science.gov (United States)

    Rovner, Mark

    Designed to increase public awareness of military spending, this 5-part guide examines the process and problems of preparing the national defense budget. The publication begins with a brief overview of the 1984 defense budget. Major military programs, trends in budgeting, and key concerns in budget formulation are explored. Graphs and charts…

  14. ERDA's Chemical Energy Storage Program

    Science.gov (United States)

    Swisher, J. H.; Kelley, J. H.

    1977-01-01

    The Chemical Energy Storage Program is described with emphasis on hydrogen storage. Storage techniques considered include pressurized hydrogen gas storage, cryogenic liquid hydrogen storage, storage in hydride compounds, and aromatic-alicyclic hydrogen storage. Some uses of energy storage are suggested. Information on hydrogen production and hydrogen use is also presented. Applications of hydrogen energy systems include storage of hydrogen for utilities load leveling, industrial marketing of hydrogen both as a chemical and as a fuel, natural gas supplementation, vehicular applications, and direct substitution for natural gas.

  15. EM-31 Alternative and Enhanced Chemical Cleaning Program

    International Nuclear Information System (INIS)

    King, Bill

    2010-01-01

    King's introduction to his presentation made 5 important points: (1) Numerous SRS tanks scheduled for closure (contract commitments); (2) Cannot remove all sludge by mechanical means due to obstructions; (3) Chemical removal technology needed (likely oxalic acid); (4) Post - dissolution neutralization required prior to transfer to compliant tanks; (5) Sodium oxalate salts precipitate on neutralization and have negative downstream impacts. There were three SRS chemical cleaning programs in 2010: Baseline: 8wt percent OA batch contact, ECC: 1-3 wt. percent OA with oxalate destruction, and the Alternative/Enhanced Chemical Cleaning (EM-31). This talk is on the EM-31 program.

  16. The Lewis Chemical Equilibrium Program with parametric study capability

    Science.gov (United States)

    Sevigny, R.

    1981-01-01

    The program was developed to determine chemical equilibrium in complex systems. Using a free energy minimization technique, the program permits calculations such as: chemical equilibrium for assigned thermodynamic states; theoretical rocket performance for both equilibrium and frozen compositions during expansion; incident and reflected shock properties; and Chapman-Jouget detonation properties. It is shown that the same program can handle solid coal in an entrained flow coal gasification problem.

  17. The WIPP research and development program: providing the technical basis for defense waste disposal

    International Nuclear Information System (INIS)

    Hunter, Th.O.

    1983-01-01

    The Waste Isolation Pilot Plant (WIPP), located in southeastern New Mexico, is being developed by the US Department of Energy as a research and development facility to demonstrate the safe disposal of radioactive wastes from the defense programs of the United States. Underground workings are at a depth of 660 in a bedded-salt formation. Site investigations began in the early 1970s and are culminating with the completion of the Site and Preliminary Design Validation (SPDV) program in 1983 in which two shafts and several thousand feet of underground drifts are being constructed. The underground facility will be used for in situ tests and demonstrations that address technical issues associated with the disposal of transuranic and defense high-level wastes (DHLW) in bedded salt. These tests are based on several years of laboratory tests, field tests in mines, and analytical modeling studies. They primarily address repository development in bedded salt, including thermal-structural interactions plugging and sealing, and facility operations; and waste package interactions, including the effects of the waste on local rock salt and the evaluation of waste package materials. In situ testing began in the WIPP with the initiation of the SPDV program in 1981. In 1983, a major series of tests will begin to investigate the response of the rock salt without the use of any radioactivity

  18. Defense programs beryllium good practice guide

    International Nuclear Information System (INIS)

    Herr, M.

    1997-07-01

    Within the DOE, it has recently become apparent that some contractor employees who have worked (or are currently working) with and around beryllium have developed chronic beryllium disease (CBD), an occupational granulomatous lung disorder. Respiratory exposure to aerosolized beryllium, in susceptible individuals, causes an immunological reaction that can result in granulomatous scarring of the lung parenchyma, shortness of breath, cough, fatigue, weight loss, and, ultimately, respiratory failure. Beryllium disease was originally identified in the 1940s, largely in the fluorescent light industry. In 1950, the Atomic Energy Commission (AEC) introduced strict exposure standards that generally curtailed both the acute and chronic forms of the disease. Beginning in 1984, with the identification of a CBD case in a DOE contractor worker, there was increased scrutiny of both industrial hygiene practices and individuals in this workforce. To date, over 100 additional cases of beryllium-specific sensitization and/or CBD have been identified. Thus, a disease previously thought to be largely eliminated by the adoption of permissible exposure standards 45 years ago is still a health risk in certain workforces. This good practice guide forms the basis of an acceptable program for controlling workplace exposure to beryllium. It provides (1) Guidance for minimizing worker exposure to beryllium in Defense Programs facilities during all phases of beryllium-related work, including the decontamination and decommissioning (D ampersand D) of facilities. (2) Recommended controls to be applied to the handling of metallic beryllium and beryllium alloys, beryllium oxide, and other beryllium compounds. (3) Recommendations for medical monitoring and surveillance of workers exposed (or potentially exposed) to beryllium, based on the best current understanding of beryllium disease and medical diagnostic tests available. (4) Site-specific safety procedures for all processes of beryllium that is

  19. The Art and Science of Defense Logistics

    Science.gov (United States)

    1995-04-01

    The Art And Science Of Defense Logistics CSC 1995 SUBJECT AREA - Logistics THE ART AND SCIENCE OF DEFENSE LOGISTICS...Government EXECUTIVE SUMMARY Title: The Art and Science of Defense Logistics Author: Major S. I. Schuler, USMC Research Questions: 1...00-1995 4. TITLE AND SUBTITLE The Art And Science Of Defense Logistics 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6

  20. Chemical process safety management within the Department of Energy

    International Nuclear Information System (INIS)

    Piatt, J.A.

    1995-07-01

    Although the Department of Energy (DOE) is not well known for its chemical processing activities, the DOE does have a variety of chemical processes covered under OSHA's Rule for Process Safety Management of Highly Hazardous Chemicals (the PSM Standard). DOE, like industry, is obligated to comply with the PSM Standard. The shift in the mission of DOE away from defense programs toward environmental restoration and waste management has affected these newly forming process safety management programs within DOE. This paper describes the progress made in implementing effective process safety management programs required by the PSM Standard and discusses some of the trends that have supported efforts to reduce chemical process risks within the DOE. In June of 1994, a survey of chemicals exceeding OSHA PSM or EPA Risk Management Program threshold quantities (TQs) at DOE sites found that there were 22 processes that utilized toxic or reactive chemicals over TQs; there were 13 processes involving flammable gases and liquids over TQs; and explosives manufacturing occurred at 4 sites. Examination of the survey results showed that 12 of the 22 processes involving toxic chemicals involved the use of chlorine for water treatment systems. The processes involving flammable gases and liquids were located at the Strategic Petroleum Reserve and Naval petroleum Reserve sites

  1. The antimicrobial resistance monitoring and research (ARMoR) program: the US Department of Defense response to escalating antimicrobial resistance.

    Science.gov (United States)

    Lesho, Emil P; Waterman, Paige E; Chukwuma, Uzo; McAuliffe, Kathryn; Neumann, Charlotte; Julius, Michael D; Crouch, Helen; Chandrasekera, Ruvani; English, Judith F; Clifford, Robert J; Kester, Kent E

    2014-08-01

    Responding to escalating antimicrobial resistance (AMR), the US Department of Defense implemented an enterprise-wide collaboration, the Antimicrobial Resistance Monitoring and Research Program, to aid in infection prevention and control. It consists of a network of epidemiologists, bioinformaticists, microbiology researchers, policy makers, hospital-based infection preventionists, and healthcare providers who collaborate to collect relevant AMR data, conduct centralized molecular characterization, and use AMR characterization feedback to implement appropriate infection prevention and control measures and influence policy. A particularly concerning type of AMR, carbapenem-resistant Enterobacteriaceae, significantly declined after the program was launched. Similarly, there have been no further reports or outbreaks of another concerning type of AMR, colistin resistance in Acinetobacter, in the Department of Defense since the program was initiated. However, bacteria containing AMR-encoding genes are increasing. To update program stakeholders and other healthcare systems facing such challenges, we describe the processes and impact of the program. Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2014. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  2. A Management Case Analysis of the Department of Defense Contractor Risk Assessment Guide Program

    Science.gov (United States)

    1990-12-01

    ORGANIZATION ......... 17 1. Past Government Organization Problems... 17 2. Current Government Organization ......... 17 3. The Contractor’s Organizatin ...Program and urged CODSIA to take a leadership role in encouraging its members to participate. The DCAA [Ref ll:p. 45] informed defense contractors in...conferences, and through the leadership of officials including the Under Secretary of the Navy for Acquisition, DOD Comptroller General, DOD Inspector General

  3. Atlantic Richfield Hanford Company chemical operator training program

    International Nuclear Information System (INIS)

    Zumhoff, R.G.

    1975-01-01

    Formal training and testing of Chemical Operators at Hanford were initiated as part of a negotiated union settlement in 1966. Consequently, it was agreed that 25 percent of the chemical operator force would receive a higher rated job (Lead Nuclear Chemical Operator) provided they satisfactorily completed a training program including testing. The training and testing program was developed in two parts. The first covered subjects of a general nature and was applicable to an operator's duties no matter what the assignment. Part II was more specifically oriented to the presently assigned work area. Renewed interest in retraining and requalification of all chemical operators was taken in 1971. This evolved from a Company concern that a program be developed to assure the fact that operators were qualified to do their assigned jobs, and an Atomic Energy Commission request for an outline of a retraining and requalification program for chemical operators. Building upon the experience gained in the LNCO (Lead Nuclear Chemical Operator) program, the two part format is retained. The use of video tapes is used to complement the manuals. An arrangement where an operator can view a lecture-type presentation is provided in seven plant locations. A small studio for in-house production of the video tapes is available to the training Specialists. A script is developed from a training manual by condensing the information into 20-minute presentations. A prime objective of each tape is to highlight the safety and control aspects that accompany operator responsibilities in each of these areas. Testing is also handled on a two part basis; one test covers the fundamentals and a separate test is designed for each of the plant subjects. A walk-through examination is also performed for the plant portion. Operators are required to be requalified on emergency procedures on an annual basis and at two-year intervals in the other areas. (U.S.)

  4. Program Manager: Journal of the Defense Systems Management College. Volume 22, Number 3, May-June 1993

    Science.gov (United States)

    1993-06-01

    lr __________ r onM eth S()4 Greg Caruth _________________ William J. Perry, Typography and Design DEPSECDEF 43 Paula Croisetlere 3 Program Manager...the DSMC Press to be such a link to the govern- for publication consideration in either the brand ment and private sector defense acquisition com- new

  5. Joint Service Chemical and Biological Defense Program: FY 06-07 Overview

    Science.gov (United States)

    2006-01-01

    Performers Molecular model of human plasma-derived butyryl Electronmicrograph of bacillus spores adhering to cell membrane processes 38866_BATT_TX 11...agents, and radioactive fallout. CPS is integrated with the ship’s Heating, Ventilation, and Air-Conditioning ( HVAC ) systems and provides filtered air...molecules for intervention against protein NTA. • Identify and evaluate effectiveness of spore germination inhibitors. • Expand drug discovery program

  6. Plutonium stabilization and storage research in the DNFSB 94-1 core technology program

    International Nuclear Information System (INIS)

    Eller, P.G.; Avens, L.R.; Roberson, G.D.

    1998-04-01

    Recommendation 94-1 of the Defense Nuclear Facility Safety Board (DNFSB) addresses legacy actinide materials left in the US nuclear defense program pipeline when the production mission ended in 1989. The Department of Energy (DOE) Implementation Plan responding to this recommendation instituted a Core Technology program to augment the knowledge base about general chemical and physical processing and storage behavior and to assure safe interim nuclear material storage, until disposition policies are formulated. The Core Technology program focuses on plutonium, in concert with a complex-wide applied R/D program administered by Los Alamos National Laboratory. This paper will summarize the Core Technology program's first two years, describe the research program for FY98, and project the overall direction of the program in the future

  7. Nuclear, Chemical and Biological Education and Training: A Review Across the Services and Joint Community

    Science.gov (United States)

    2007-09-01

    13 1. Air Force Inspector General – CBRNE CERFP Program Audit ...14 2. Defense Medical...CBRNE CERFP Program Audit “The AFAA [Air Force Audit Agency] is assessing whether Air National Guard officials properly managed the Chemical...processing personnel through the aircrew contamination control area ( ACCA ). Flight Medicine provides training on agent toxicology and pharmacology. The

  8. CHEMSIMUL - A program package for numerical simulation of chemical reaction systems

    International Nuclear Information System (INIS)

    Lang Rasmussen, O.; Bjergbakke, E.

    1984-01-01

    A description is given of a program package, CHEMSIMUL, for numerical simulation of chemical reaction systems. The main components in the package are a translator of chemical equations to differential equations, a balance equation program, a differential equation solver, EPISODE, and an input/output program. The performance of the program is demonstrated by four examples. A manual for the input file and the complete program text with comments are given in Appendices I and II. (author)

  9. Defense pattern of Chinese cork oak across latitudinal gradients: influences of ontogeny, herbivory, climate and soil nutrients

    Science.gov (United States)

    Wang, Xiao-Fei; Liu, Jian-Feng; Gao, Wen-Qiang; Deng, Yun-Peng; Ni, Yan-Yan; Xiao, Yi-Hua; Kang, Feng-Feng; Wang, Qi; Lei, Jing-Pin; Jiang, Ze-Ping

    2016-06-01

    Knowledge of latitudinal patterns in plant defense and herbivory is crucial for understanding the mechanisms that govern ecosystem functioning and for predicting their responses to climate change. Using a widely distributed species in East Asia, Quercus variabilis, we aim to reveal defense patterns of trees with respect to ontogeny along latitudinal gradients. Six leaf chemical (total phenolics and total condensed tannin concentrations) and physical (cellulose, hemicellulose, lignin and dry mass concentration) defensive traits as well as leaf herbivory (% leaf area loss) were investigated in natural Chinese cork oak (Q. variabilis) forests across two ontogenetic stages (juvenile and mature trees) along a ~14°-latitudinal gradient. Our results showed that juveniles had higher herbivory values and a higher concentration of leaf chemical defense substances compared with mature trees across the latitudinal gradient. In addition, chemical defense and herbivory in both ontogenetic stages decreased with increasing latitude, which supports the latitudinal herbivory-defense hypothesis and optimal defense theory. The identified trade-offs between chemical and physical defense were primarily determined by environmental variation associated with the latitudinal gradient, with the climatic factors (annual precipitation, minimum temperature of the coldest month) largely contributing to the latitudinal defense pattern in both juvenile and mature oak trees.

  10. Defense Acquisitions Acronyms and Terms

    Science.gov (United States)

    2012-12-01

    DR Decision Review DRMO Defense Reutilization Marketing Office DRPM Direct Reporting Program Manager DSAA Defense Security Assistance Agency...STE Special Test Equipment STEP Simulation, Test, and Evaluation Process STLDD Software Top Level Design Document STP Software Test Plan STPR...established catalog or market prices for specific tasks under standard commercial terms and conditions; this does not include services sold based

  11. Defense programs business practices re-engineering QFD exercise

    International Nuclear Information System (INIS)

    Murray, C.; Halbleib, L.

    1996-03-01

    The end of the cold war has resulted in many changes for the Nuclear Weapons Complex (NWC). We now work in a smaller complex, with reduced resources, a smaller stockpile, and no new phase 3 weapons development programs. This new environment demands that we re-evaluate the way we design and produce nuclear weapons. The Defense Program (DP) Business Practices Re-engineering activity was initiated to improve the design and production efficiency of the DP Sector. The activity had six goals: (1) to identify DP business practices that are exercised by the Product Realization Process (PRP); (2) to determine the impact (positive, negative, or none) of these practices on defined, prioritized customer criteria; (3) to identify business practices that are candidates for elimination or re-engineering; (4) to select two or three business practices for re-engineering; (5) to re-engineer the selected business practices; and (6) to exercise the re-engineered practices on three pilot development projects. Business practices include technical and well as administrative procedures that are exercised by the PRP. A QFD exercise was performed to address (1)-(4). The customer that identified, defined, and prioritized the criteria to rate the business practices was the Block Change Advisory Group. Five criteria were identified: cycle time, flexibility, cost, product performance/quality, and best practices. Forty-nine business practices were identified and rated per the criteria. From this analysis, the group made preliminary recommendations as to which practices would be addressed in the re-engineering activity. Sixteen practices will be addressed in the re-engineering activity. These practices will then be piloted on three projects: (1) the Electronic Component Assembly (ECA)/Radar Project, (2) the B61 Mod 11, and (3) Warhead Protection Program (WPP)

  12. Status of DOE defense waste management policy

    International Nuclear Information System (INIS)

    Oertel, K.G.; Scott, R.S.

    1983-01-01

    This paper very briefly traces the statutory basis for DOE management of atomic energy defense activity wastes, touches on the authority of the Federal agencies involved in the regulation of defense nuclear waste management, and addresses the applicable regulations and their status. This background sets the stage for a fairly detailed discussion of management and disposal strategies of the Defense Waste and Byproducts Management Program

  13. A Goal Programming R&D (Research and Development) Project Funding Model of the U.S. Army Strategic Defense Command Using the Analytic Hierarchy Process.

    Science.gov (United States)

    1987-09-01

    A187 899 A GOAL PROGRANNIN R&D (RESEARCH AND DEVELOPMENT) 1/2 PROJECT FUNDING MODEL 0 (U) NAVAL POSTGRADUATE SCHOOL MONTEREY CA S M ANDERSON SEP 87...PROGRAMMING R&D PROJECT FUNDING MODEL OF THE U.S. ARMY STRATEGIC DEFENSE COMMAND USING THE ANALYTIC HIERARCHY PROCESS by Steven M. Anderson September 1987...jACCESSION NO TITI E (Influde Securt ClauAIcatsrn) A Goal Programming R&D Project Funding Model of the U.S. Army Strategic Defense Command Using the

  14. Prepublication Review of Government Employee Speech: A Case Study of the Department of Defense and United States Air Force Security/Policy Review Programs.

    Science.gov (United States)

    Warden, Michael L.

    Since 1957 the Department of Defense has subjected all forms of speech of U.S. military personnel meant for publication to prepublication review based on security and policy criteria. The historical development of the Defense Department's prepublication review program and its specific implementation by the U.S. Air Force lead to questions of First…

  15. Nuclear, biological and chemical contamination survivability of Army material

    International Nuclear Information System (INIS)

    Feeney, J.J.

    1987-01-01

    Army Regulation (AR) 70-71, Nuclear, Biological and Chemical (NBC) Contamination Survivability of Army Material, published during 1984, establishes Army policy and procedures for the development and acquisition of material to ensure its survivablility and sustainability on the NBC-contaminated battlefield. This regulation defines NBC contamination as a term that includes both the individual and collective effects of residual radiological, biological, and chemical contamination. AR 70-71 applies to all mission-essential equipment within the Army. NBC contamination survivability is the capability of a system and its crew to withstand an NBC-contaminated environment, including decontamination, without losing the ability to accomplish the assigned mission. Characteristics of NBC contamination survivability are decontaminability, hardness, and compatability. These characteristics are engineering design criteria which are intended for use only in a developmental setting. To comply with AR 70-71, each mission-essential item must address all three criteria. The Department of Defense (DOD) has published a draft instruction addressing acquisition of NBC contamination survivable systems. This instruction will apply throughout DOD to those programs, systems and subsystems designated by the Secretary of Defense as major systems acquisition programs and to those non-major systems that have potential impact on critical functions

  16. Defense Enterprise Accounting and Management System-Increment 1 (DEAMS Inc 1)

    Science.gov (United States)

    2016-03-01

    information accurately and in conformance with Generally Accepted Accounting Principles , to comply with Congressional requirements of the Chief Financial ...2016 Major Automated Information System Annual Report Defense Enterprise Accounting and Management System-Increment 1 (DEAMS Inc 1) Defense...Phone: 937-257-2714 Fax: DSN Phone: 787-2714 DSN Fax: Date Assigned: August 17, 2015 Program Information Program Name Defense Enterprise Accounting

  17. Defense Health Program Financial Reporting of General Property, Plant, and Equipment

    National Research Council Canada - National Science Library

    Lane, F

    2000-01-01

    .... The DoD Agency Wide financial statements include financial statements for a reporting entity called "Other Defense Organizations," a consolidation of financial information from various Defense...

  18. Massachusetts Institute of Technology Defense & Arms Control Studies Program

    Science.gov (United States)

    1996-01-01

    security of the nation. The unicorn is the obvious symbol for this box. Even with a two percent of GDP or less defense budget, we will maintain our nuclear...systems is not going away. There are some unicorns in the defense herd and this would be a time to claim to be one. ACTIVITIES AND PERSONNEL Looking...macroeconomics and public finance is advisable. The subjects in the Forces and Force Analysis section will provide sufficient review of the technical

  19. Balancing the technical, administrative, and institutional forces in defense waste management

    International Nuclear Information System (INIS)

    Hindman, T.B.

    1988-01-01

    Defense radioactive waste results from the Department of Energy's (DOE) national defense and nuclear weapons production activities. In 1983, the President submitted to Congress the Defense Waste Management Plan (DWMP) for defense high-level and transuranic wastes. The Plan proposed a workable approach for the final disposition of these wastes. The Department is still following the path laid out in this Plan. The proper management of this waste requires that technical, administrative, and institutional forces which are often neither well understood nor well documented be properly balanced. This paper clarifies the role these three forces play in the Defense waste management programs and provides examples of their impacts on specific programs

  20. Applying Rapid Acquisition Policy Lessons for Defense Innovation

    Science.gov (United States)

    2017-12-21

    import- ing Silicon Valley- style innovation practices to its acquisition process, it is im- portant to assess an organization’s ability to...these efforts. Keywords: defense acquisition, defense procurement, rapid acquisition, de- fense innovation, program management , organizational culture...Device De- feat Organization, JIEDDO, Rapid Equipping Force, REF Silicon Valley- style innovation is a hot topic in the Department of De-fense (DOD). For

  1. Planning guidance for the Chemical Stockpile Emergency Preparedness Program

    Energy Technology Data Exchange (ETDEWEB)

    Shumpert, B.L.; Watson, A.P.; Sorensen, J.H. [and others

    1995-02-01

    This planning guide was developed under the direction of the U.S. Army and the Federal Emergency Management Agency (FEMA) which jointly coordinate and direct the development of the Chemical Stockpile Emergency Preparedness Program (CSEPP). It was produced to assist state, local, and Army installation planners in formulating and coordinating plans for chemical events that may occur at the chemical agent stockpile storage locations in the continental United States. This document provides broad planning guidance for use by both on-post and off-post agencies and organizations in the development of a coordinated plan for responding to chemical events. It contains checklists to assist in assuring that all important aspects are included in the plans and procedures developed at each Chemical Stockpile Disposal Program (CSDP) location. The checklists are supplemented by planning guidelines in the appendices which provide more detailed guidance regarding some issues. The planning guidance contained in this document will help ensure that adequate coordination between on-post and off-post planners occurs during the planning process. This planning guide broadly describes an adequate emergency planning base that assures that critical planning decisions will be made consistently at every chemical agent stockpile location. This planning guide includes material drawn from other documents developed by the FEMA, the Army, and other federal agencies with emergency preparedness program responsibilities. Some of this material has been developed specifically to meet the unique requirements of the CSEPP. In addition to this guidance, other location-specific documents, technical studies, and support studies should be used as needed to assist in the planning at each of the chemical agent stockpile locations to address the specific hazards and conditions at each location.

  2. Analysis and Evaluation of Forecasting Methods and Tools to Predict Future Demand for Secondary Chemical-Biological Configuration Items

    Science.gov (United States)

    2013-06-01

    Depot Level Reparable DO Due Out DoD Department of Defense ECBC Edgewood Chemical Biological Center EOQ Economic Order Quantity ERP Enterprise...Objective ROP Reorder Point SAP Security Assistance Program SL Safety Level SPR Special Program Request TACOM U.S. Army Tank-automotive and...Security Assistance Program ( SAP ); items only for SAP Q Bulk Petroleum Products. DLA-managed R Restricted Requisition – Government Furnished Material

  3. Defense Transportation; The Army

    National Research Council Canada - National Science Library

    1998-01-01

    .... The statement of managers in the conference report on the Department of Defense Appropriations Act, 1997, directed us to validate the results and savings achieved from this and any other personal property pilot program...

  4. United States Food and Drug Administration and Department of Defense shelf-life extension program of pharmaceutical products: progress and promise.

    Science.gov (United States)

    Khan, Saeed R; Kona, Ravikanth; Faustino, Patrick J; Gupta, Abhay; Taylor, Jeb S; Porter, Donna A; Khan, Mansoor

    2014-05-01

    The Department of Defense (DoD)-United States Food and Drug Administration (FDA) shelf-life extension program (SLEP) was established in 1986 through an intra-agency agreement between the DoD and the FDA to extend the shelf life of product nearing expiry. During the early stages of development, special attention was paid to program operation, labeling requirements, and the cost benefits associated with this program. In addition to the substantial cost benefits, the program also provides the FDA's Center for Drug Evaluation and Research with significant scientific understanding and pharmaceutical resource. As a result of this unique resource, numerous regulatory research opportunities to improve public health present themselves from this distinctive scientific database, which includes examples of products shelf life, their long-term stability issues, and various physical and chemical tests to identify such failures. The database also serves as a scientific resource for mechanistic understanding and identification of test failures leading to the development of new formulations or more robust packaging. It has been recognized that SLEP is very important in maintaining both national security and public welfare by confirming that the stockpiled pharmaceutical products meet quality standards after the "expiration date" assigned by the sponsor. SLEP research is an example of regulatory science that is needed to best ensure product performance past the original shelf life. The objective of this article is to provide a brief history and background and most importantly the public health benefits of the SLEP. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

  5. Program Management at the National Nuclear Security Administration Office of Defense Nuclear Security: A Review of Program Management Documents and Underlying Processes

    International Nuclear Information System (INIS)

    Madden, Michael S.

    2010-01-01

    The scope of this paper is to review the National Nuclear Security Administration Office of Defense Nuclear Security (DNS) program management documents and to examine the underlying processes. The purpose is to identify recommendations for improvement and to influence the rewrite of the DNS Program Management Plan (PMP) and the documentation supporting it. As a part of this process, over 40 documents required by DNS or its stakeholders were reviewed. In addition, approximately 12 other documents produced outside of DNS and its stakeholders were reviewed in an effort to identify best practices. The complete list of documents reviewed is provided as an attachment to this paper.

  6. 75 FR 33271 - Information Collection Requirement; Defense Federal Acquisition Regulation Supplement; Foreign...

    Science.gov (United States)

    2010-06-11

    ... Certain Contracts with Foreign Entities for the Conduct of Ballistic Missile Defense Research, Development..., development, test, or evaluation in connection with the Ballistic Missile Defense Program. The provision... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System [OMB Control Number 0704-0229...

  7. Applicability of federal and state hazardous waste regulatory programs to waste chemical weapons and chemical warfare agents.; TOPICAL

    International Nuclear Information System (INIS)

    Haffenden, R.; Kimmell, T.

    2002-01-01

    This report reviews federal and state hazardous waste regulatory programs that govern the management of chemical weapons or chemical warfare agents. It addresses state programs in the eight states with chemical weapon storage facilities managed by the U.S. Army: Alabama, Arkansas, Colorado, Indiana, Kentucky, Maryland, Oregon, and Utah. It also includes discussions on 32 additional states or jurisdictions with known or suspected chemical weapons or chemical warfare agent presence (e.g., disposal sites containing chemical agent identification sets): Alaska, Arizona, California, Florida, Georgia, Hawaii, Idaho, Illinois, Iowa, Kansas, Louisiana, Massachusetts, Michigan, Mississippi, Missouri, Nebraska, Nevada, New Jersey, New Mexico, New York, North Carolina, Ohio, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, the U.S. Virgin Islands, Virginia, Washington, Washington, D.C., and Wyoming. Resource Conservation and Recovery Act (RCRA) hazardous waste programs are reviewed to determine whether chemical weapons or chemical warfare agents are listed hazardous wastes or otherwise defined or identified as hazardous wastes. Because the U.S. Environmental Protection Agency (EPA) military munitions rule specifically addresses the management of chemical munitions, this report also indicates whether a state has adopted the rule and whether the resulting state regulations have been authorized by EPA. Many states have adopted parts or all of the EPA munitions rule but have not yet received authorization from EPA to implement the rule. In these cases, the states may enforce the adopted munitions rule provisions under state law, but these provisions are not federally enforceable

  8. Defense Department funds advanced military wireless networks research

    OpenAIRE

    Crumbley, Liz

    2005-01-01

    The U.S. Department of Defense has awarded a $246,000 Defense University Research Instrumentation Program (DURIP) grant to researchers in Virginia Tech's Bradley Department of Electrical and Computer Engineering for advanced research on wireless communications networks that are critical during military maneuvers.

  9. Integration of long-range planning for management of defense transuranic waste

    International Nuclear Information System (INIS)

    Gilbert, K.V.; McFadden, M.H.; Raudenbush, M.H.; Smith, L.J.

    1984-01-01

    As described in The Defense Waste Management Plan, the defense TRU program goal is to achieve permanent disposal and to end interim storage. TRU waste is currently stored at six Department of Energy (DOE) sites, and new waste is generated at several more sites. The Waste Isolation Pilot Plant (WIPP) project is well defined, and it has been necessary to integrate the activities of other parts of the TRU program in support of DOE Headquarters policy and the WIPP schedules and technical requirements. The strategy is described in the Defense Transuranic Waste Program Strategy Document. More detailed, quantitative plans have been developed through the use of several system models, with a Long-Range Master Plan for Defense Transuranic Waste Management as the focal point for coordination of proposed plans with all the parties involved

  10. Effector-triggered immunity: from pathogen perception to robust defense.

    Science.gov (United States)

    Cui, Haitao; Tsuda, Kenichi; Parker, Jane E

    2015-01-01

    In plant innate immunity, individual cells have the capacity to sense and respond to pathogen attack. Intracellular recognition mechanisms have evolved to intercept perturbations by pathogen virulence factors (effectors) early in host infection and convert it to rapid defense. One key to resistance success is a polymorphic family of intracellular nucleotide-binding/leucine-rich-repeat (NLR) receptors that detect effector interference in different parts of the cell. Effector-activated NLRs connect, in various ways, to a conserved basal resistance network in order to transcriptionally boost defense programs. Effector-triggered immunity displays remarkable robustness against pathogen disturbance, in part by employing compensatory mechanisms within the defense network. Also, the mobility of some NLRs and coordination of resistance pathways across cell compartments provides flexibility to fine-tune immune outputs. Furthermore, a number of NLRs function close to the nuclear chromatin by balancing actions of defense-repressing and defense-activating transcription factors to program cells dynamically for effective disease resistance.

  11. Audit of Major Defense Acquisition Programs Cycle Time

    National Research Council Canada - National Science Library

    Ugone, Mary

    2001-01-01

    ... (GPRA) as indicated in the FY 2000 Annual Report of the Secretary of Defense. Specifically, we assessed whether the process and factors, used to establish the metric goal of MDAP cycle time, were valid...

  12. Acquisition: Acquisition of Targets at the Missile Defense Agency

    National Research Council Canada - National Science Library

    Ugone, Mary L; Meling, John E; James, Harold C; Haynes, Christine L; Heller, Brad M; Pomietto, Kenneth M; Bobbio, Jaime; Chang, Bill; Pugh, Jacqueline

    2005-01-01

    Who Should Read This Report and Why? Missile Defense Agency program managers who are responsible for the acquisition and management of targets used to test the Ballistic Missile Defense System should be interested in this report...

  13. Chemical inventory control program for mixed and hazardous waste facilities at SRS

    International Nuclear Information System (INIS)

    Ades, M.J.; Vincent, A.M. III.

    1997-01-01

    Mixed Waste (MW) and Hazardous Waste (HW) are being stored at the Savannah River Site (SRS) pending onsite and/or offsite treatment and disposal. The inventory control for these wastes has recently been brought under Technical Safety Requirements (TSR) in accordance with DOE Order 5480.22. With the TSRs was the question of the degree of rigor with which the inventory is to be tracked, considering that the variety of chemicals present, or that could be present, numbers in the hundreds. This paper describes the graded approach program to track Solid Waste (SW) inventories relative to TSRs. The approach uses a ratio of the maximum anticipated chemical inventory to the permissible inventory in accordance with Emergency Response Planning Guideline (ERPG) limits for on- and off-site receptors. A specific threshold ratio can then be determined. The chemicals above this threshold ratio are to be included in the chemical inventory control program. The chemicals that fall below the threshold ratio are managed in accordance with existing practice per State and RCRA hazardous materials requirements. Additionally, the facilities are managed in accordance with process safety management principles, specifically using process hazards analyses, which provides safety assurance for even the small quantities that may be excluded from the formal inventory control program. The method yields a practical approach to chemical inventory control, while maintaining appropriate chemical safety margins. The resulting number of specific chemicals that require inclusion in a rigorous inventory control program is greatly reduced by about 80%, thereby resulting in significant reduction in chemical data management while preserving appropriate safety margins

  14. Implementation plan for the Defense Nuclear Facilities Safety Board Recommendation 90-7

    International Nuclear Information System (INIS)

    Borsheim, G.L.; Cash, R.J.; Dukelow, G.T.

    1992-12-01

    This document revises the original plan submitted in March 1991 for implementing the recommendations made by the Defense Nuclear Facilities Safety Board in their Recommendation 90-7 to the US Department of Energy. Recommendation 90-7 addresses safety issues of concern for 24 single-shell, high-level radioactive waste tanks containing ferrocyanide compounds at the Hanford Site. The waste in these tanks is a potential safety concern because, under certain conditions involving elevated temperatures and low concentrations of nonparticipating diluents, ferrocyanide compounds in the presence of oxidizing materials can undergo a runaway (propagating) chemical reaction. This document describes those activities underway by the Hanford Site contractor responsible for waste tank safety that address each of the six parts of Defense Nuclear Facilities Safety Board Recommendation 90-7. This document also identifies the progress made on these activities since the beginning of the ferrocyanide safety program in September 1990. Revised schedules for planned activities are also included

  15. Dilute chemical decontamination program review

    International Nuclear Information System (INIS)

    Anstine, L.D.; Blomgren, J.C.; Pettit, P.J.

    1980-01-01

    The objective of the Dilute Chemical Decontamination Program is to develop and evaluate a process which utilizes reagents in dilute concentrations for the decontamination of BWR primary systems and for the maintenance of dose rates on the out-of-core surfaces at acceptable levels. A discussion is presented of the process concept, solvent development, advantages and disadvantages of reagent systems, and VNC loop tests. Based on the work completed to date it is concluded that (1) rapid decontamination of BWRs using dilute reagents is feasible; (2) reasonable reagent conditions for rapid chemical decontamination are: 0.01M oxalic acid + 0.005M citric acid, pH3.0, 90/degree/C, 0.5 to 1.0 ppm dissolved oxygen; (3) control of dissolved oxygen concentration is important, since high levels suppress the rate of decontamination and low levels allow precipitation of ferrous oxalate. 4 refs

  16. Systems analysis of past, present, and future chemical terrorism scenarios.

    Energy Technology Data Exchange (ETDEWEB)

    Hoette, Trisha Marie

    2012-03-01

    Throughout history, as new chemical threats arose, strategies for the defense against chemical attacks have also evolved. As a part of an Early Career Laboratory Directed Research and Development project, a systems analysis of past, present, and future chemical terrorism scenarios was performed to understand how the chemical threats and attack strategies change over time. For the analysis, the difficulty in executing chemical attack was evaluated within a framework of three major scenario elements. First, historical examples of chemical terrorism were examined to determine how the use of chemical threats, versus other weapons, contributed to the successful execution of the attack. Using the same framework, the future of chemical terrorism was assessed with respect to the impact of globalization and new technologies. Finally, the efficacy of the current defenses against contemporary chemical terrorism was considered briefly. The results of this analysis justify the need for continued diligence in chemical defense.

  17. Feeding preferences of the endemic gastropod Astraea latispina in relation to chemical defenses of Brazilian tropical seaweeds

    Directory of Open Access Journals (Sweden)

    PEREIRA R. C.

    2002-01-01

    Full Text Available Seaweed preference by the Brazilian endemic gastropod Astraea latispina was examined in the laboratory to evaluate the role of secondary metabolites in determining food choice. Of three species of seaweeds examined, Plocamium brasiliense was highly preferred; less so were Sargassum furcatum and Dictyota cervicornis were preferred less. Extracts and/or pure major metabolites of the two potentially chemically-defended seaweeds (P. brasiliense and D. cervicornis were tested as feeding deterrents against A. latispina. Algal extract assays demonstrated that three concentrations of crude organic extract of the red alga P. brasiliense (50%, 100%: natural concentration, and 200% of dry weight: dw did not affect feeding of this gastropod. In contrast, the three concentrations of crude organic extract of the brown alga D. cervicornis (50%, 100% and 200% dw inhibited feeding by A. latispina. The chemical deterrent property of D. cervicornis extract against the gastropod A. latispina occurred due to a mixture of the secodolastane diterpenes isolinearol/linearol (4:1 -- 0.08% dry weight. This is the first report showing that Dictyota cervicornis produces a chemical defense against herbivores using secodolastane diterpenoid. In addition, these results widen the action spectrum of secondary metabolites found in seaweed belonging to this brown algal genus.

  18. Feeding preferences of the endemic gastropod Astraea latispina in relation to chemical defenses of Brazilian tropical seaweeds

    Directory of Open Access Journals (Sweden)

    R. C. PEREIRA

    Full Text Available Seaweed preference by the Brazilian endemic gastropod Astraea latispina was examined in the laboratory to evaluate the role of secondary metabolites in determining food choice. Of three species of seaweeds examined, Plocamium brasiliense was highly preferred; less so were Sargassum furcatum and Dictyota cervicornis were preferred less. Extracts and/or pure major metabolites of the two potentially chemically-defended seaweeds (P. brasiliense and D. cervicornis were tested as feeding deterrents against A. latispina. Algal extract assays demonstrated that three concentrations of crude organic extract of the red alga P. brasiliense (50%, 100%: natural concentration, and 200% of dry weight: dw did not affect feeding of this gastropod. In contrast, the three concentrations of crude organic extract of the brown alga D. cervicornis (50%, 100% and 200% dw inhibited feeding by A. latispina. The chemical deterrent property of D. cervicornis extract against the gastropod A. latispina occurred due to a mixture of the secodolastane diterpenes isolinearol/linearol (4:1 -- 0.08% dry weight. This is the first report showing that Dictyota cervicornis produces a chemical defense against herbivores using secodolastane diterpenoid. In addition, these results widen the action spectrum of secondary metabolites found in seaweed belonging to this brown algal genus.

  19. Costs of jasmonic acid induced defense in aboveground and belowground parts of corn (Zea mays L.).

    Science.gov (United States)

    Feng, Yuanjiao; Wang, Jianwu; Luo, Shiming; Fan, Huizhi; Jin, Qiong

    2012-08-01

    Costs of jasmonic acid (JA) induced plant defense have gained increasing attention. In this study, JA was applied continuously to the aboveground (AG) or belowground (BG) parts, or AG plus BG parts of corn (Zea mays L.) to investigate whether JA exposure in one part of the plant would affect defense responses in another part, and whether or not JA induced defense would incur allocation costs. The results indicated that continuous JA application to AG parts systemically affected the quantities of defense chemicals in the roots, and vice versa. Quantities of DIMBOA and total amounts of phenolic compounds in leaves or roots generally increased 2 or 4 wk after the JA treatment to different plant parts. In the first 2 wk after application, the increase of defense chemicals in leaves and roots was accompanied by a significant decrease of root length, root surface area, and root biomass. Four weeks after the JA application, however, no such costs for the increase of defense chemicals in leaves and roots were detected. Instead, shoot biomass and root biomass increased. The results suggest that JA as a defense signal can be transferred from AG parts to BG parts of corn, and vice versa. Costs for induced defense elicited by continuous JA application were found in the early 2 wk, while distinct benefits were observed later, i.e., 4 wk after JA treatment.

  20. Polyphenol Oxidase as a Biochemical Seed Defense Mechanism

    Directory of Open Access Journals (Sweden)

    E. Patrick Fuerst

    2014-12-01

    Full Text Available Seed dormancy and resistance to decay are fundamental survival strategies, which allow a population of seeds to germinate over long periods of time. Seeds have physical, chemical, and biological defense mechanisms that protect their food reserves from decay-inducing organisms and herbivores. Here, we hypothesize that seeds also possess enzyme-based biochemical defenses, based on induction of the plant defense enzyme, polyphenol oxidase (PPO, when wild oat (Avena fatua L. caryopses and seeds were challenged with seed-decaying Fusarium fungi. These studies suggest that dormant seeds are capable of mounting a defense response to pathogens. The pathogen-induced PPO activity from wild oat was attributed to a soluble isoform of the enzyme that appeared to result, at least in part, from proteolytic activation of a latent PPO isoform. PPO activity was also induced in wild oat hulls (lemma and palea, non-living tissues that cover and protect the caryopsis. These results are consistent with the hypothesis that seeds possess inducible enzyme-based biochemical defenses arrayed on the exterior of seeds and these defenses represent a fundamental mechanism of seed survival and longevity in the soil. Enzyme-based biochemical defenses may have broader implications since they may apply to other defense enzymes as well as to a diversity of plant species and ecosystems.

  1. Metabolomics to Decipher the Chemical Defense of Cereals against Fusarium graminearum and Deoxynivalenol Accumulation

    Directory of Open Access Journals (Sweden)

    Léa Gauthier

    2015-10-01

    Full Text Available Fusarium graminearum is the causal agent of Fusarium head blight (FHB and Gibberella ear rot (GER, two devastating diseases of wheat, barley, and maize. Furthermore, F. graminearum species can produce type B trichothecene mycotoxins that accumulate in grains. Use of FHB and GER resistant cultivars is one of the most promising strategies to reduce damage induced by F. graminearum. Combined with genetic approaches, metabolomic ones can provide powerful opportunities for plant breeding through the identification of resistant biomarker metabolites which have the advantage of integrating the genetic background and the influence of the environment. In the past decade, several metabolomics attempts have been made to decipher the chemical defense that cereals employ to counteract F. graminearum. By covering the major classes of metabolites that have been highlighted and addressing their potential role, this review demonstrates the complex and integrated network of events that cereals can orchestrate to resist to F. graminearum.

  2. Metabolomics to Decipher the Chemical Defense of Cereals against Fusarium graminearum and Deoxynivalenol Accumulation

    Science.gov (United States)

    Gauthier, Léa; Atanasova-Penichon, Vessela; Chéreau, Sylvain; Richard-Forget, Florence

    2015-01-01

    Fusarium graminearum is the causal agent of Fusarium head blight (FHB) and Gibberella ear rot (GER), two devastating diseases of wheat, barley, and maize. Furthermore, F. graminearum species can produce type B trichothecene mycotoxins that accumulate in grains. Use of FHB and GER resistant cultivars is one of the most promising strategies to reduce damage induced by F. graminearum. Combined with genetic approaches, metabolomic ones can provide powerful opportunities for plant breeding through the identification of resistant biomarker metabolites which have the advantage of integrating the genetic background and the influence of the environment. In the past decade, several metabolomics attempts have been made to decipher the chemical defense that cereals employ to counteract F. graminearum. By covering the major classes of metabolites that have been highlighted and addressing their potential role, this review demonstrates the complex and integrated network of events that cereals can orchestrate to resist to F. graminearum. PMID:26492237

  3. 75 FR 18850 - National Protection and Programs Directorate; Chemical Facility Anti-Terrorism Standards...

    Science.gov (United States)

    2010-04-13

    ... Directorate; Chemical Facility Anti-Terrorism Standards Personnel Surety Program AGENCY: National Protection...-terrorism Vulnerability Information (CVI), Sensitive Security Information (SSI), or Protected Critical... . SUPPLEMENTARY INFORMATION: Program Description The Chemical Facility Anti-Terrorism Standards (CFATS), 6 CFR...

  4. Designing chemical soil characterization programs for mixed waste sites

    International Nuclear Information System (INIS)

    Meyers, K.A. Jr.

    1989-01-01

    The Weldon Spring Site Remedial Action Project is a remedial action effort funded by the U.S. Department of Energy. The Weldon Spring Site, a former uranium processing facility, is located in east-central Missouri on a portion of a former ordnance works facility which produced trinitrotoluene during World War II. As a result of both uranium and ordnance production, the soils have become both radiologically and chemically contaminated. As a part of site characterization efforts in support of the environmental documentation process, a chemical soil characterization program was developed. This program consisted of biased and unbiased sampling program which maximized areal coverage, provided a statistically sound data base and maintained cost effectiveness. This paper discusses how the general rationale and processes used at the Weldon Spring Site can be applied to other mixed and hazardous waste sites

  5. NATO and U.S. Ballistic Missile Defense Programs: Divergent or Convergent Paths?

    National Research Council Canada - National Science Library

    Toms, Kevin E

    2008-01-01

    ...) information network to support the Theater Missile Defense (TMD) capabilities of specific Allies for the protection of forward deployed troops, and studies of the feasibility and political-military implications of Ballistic Missile Defense (BMD...

  6. Activities in department of energy hazardous and mixed waste defense waste management

    International Nuclear Information System (INIS)

    Eyman, L.D.

    1988-01-01

    In January 1986, the U.S. Department of Energy (DOE) Office of Assistant Secretary for Defense Programs (DP) created the Hazardous Waste and Remedial Actions Division within the Office of Defense Waste and Transportation Management. The Oak Ridge Operations Office (ORO) was assigned the responsibility for supporting DOE Headquarters (HQ) in planning nationally integrated activities for Resource Conservation and Recovery Act/Comprehensive Environmental Response, Compensation, and Liability Act/Superfund Amendments and Reauthorization Act (RCRA/CERCLA/SARA) compliance. In turn, ORO created the Hazardous Waste Remedial Actions Program Support Contractor Office (HAZWRAPSCO) to assist with the expanded lead assignment. The HAZWRAPSCO activities are currently supported by three distinct DOE-HQ funding elements: the Environmental Restoration Program, the Hazardous Waste Compliance Technology Program, and the Hazardous Waste Research and Development R and D Program. The Environmental Restoration Program is discussed in the paper, entitled The DOE Defense Program for Environmental Restoration

  7. Preliminary assessment of the aquatic impacts of a proposed defense waste processing facility at the Savannah River Plant

    International Nuclear Information System (INIS)

    Mackey, H.E. Jr.

    1979-01-01

    A review of the literature indicates that a significant body of descriptive information exists concerning the aquatic ecology of Upper Three Runs Creek and Four Mile Creek of the Savannah River Plant south of Aiken, South Carolina. This information is adequate for preparation of an environmental document evaluating these streams. These streams will be impacted by construction and operation of a proposed Defense Waste Processing Facility for solidification of high level defense waste. Potential impacts include (1) construction runoff, erosion, and siltation, (2) effluents from a chemical and industrial waste treatment facility, and (3) radionuclide releases. In order to better evaluate potential impacts, recommend mitigation methods, and comply with NEPA requirements, additional quantitative biological information should be obtained through implementation of an aquatic baseline program

  8. Preliminary assessment of the aquatic impacts of a proposed defense waste processing facility at the Savannah River Plant

    Energy Technology Data Exchange (ETDEWEB)

    Mackey, H.E. Jr.

    1979-01-01

    A review of the literature indicates that a significant body of descriptive information exists concerning the aquatic ecology of Upper Three Runs Creek and Four Mile Creek of the Savannah River Plant south of Aiken, South Carolina. This information is adequate for preparation of an environmental document evaluating these streams. These streams will be impacted by construction and operation of a proposed Defense Waste Processing Facility for solidification of high level defense waste. Potential impacts include (1) construction runoff, erosion, and siltation, (2) effluents from a chemical and industrial waste treatment facility, and (3) radionuclide releases. In order to better evaluate potential impacts, recommend mitigation methods, and comply with NEPA requirements, additional quantitative biological information should be obtained through implementation of an aquatic baseline program.

  9. Space-based ballistic-missile defense

    International Nuclear Information System (INIS)

    Bethe, H.A.; Garwin, R.L.; Gottfried, K.; Kendall, H.W.

    1984-01-01

    This article, based on a forthcoming book by the Union for Concerned Scientists, focuses on the technical aspects of the issue of space-based ballistic-missile defense. After analysis, the authors conclude that the questionable performance of the proposed defense, the ease with which it could be overwhelmed or circumvented, and its potential as an antisatellite system would cause grievous damage to the security of the US if the Strategic Defense Initiative were to be pursued. The path toward greater security lies in quite another direction, they feel. Although research on ballistic-missile defense should continue at the traditional level of expenditure and within the constraints of the ABM Treaty, every effort should be made to negotiate a bilateral ban on the testing and use of space weapons. The authors think it is essential that such an agreement cover all altitudes, because a ban on high-altitude antisatellite weapons alone would not viable if directed energy weapons were developed for ballistic-missile defense. Further, the Star Wars program, unlikely ever to protect the entire nation against a nuclear attack, would nonetheless trigger a major expansion of the arms race

  10. 48 CFR 225.7016 - Restriction on Ballistic Missile Defense research, development, test, and evaluation.

    Science.gov (United States)

    2010-10-01

    ... Missile Defense research, development, test, and evaluation. 225.7016 Section 225.7016 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS... Acquisition 225.7016 Restriction on Ballistic Missile Defense research, development, test, and evaluation. [68...

  11. Subsurface transport program: Research summary

    International Nuclear Information System (INIS)

    1987-01-01

    DOE's research program in subsurface transport is designed to provide a base of fundamental scientific information so that the geochemical, hydrological, and biological mechanisms that contribute to the transport and long term fate of energy related contaminants in subsurface ecosystems can be understood. Understanding the physical and chemical mechanisms that control the transport of single and co-contaminants is the underlying concern of the program. Particular attention is given to interdisciplinary research and to geosphere-biosphere interactions. The scientific results of the program will contribute to resolving Departmental questions related to the disposal of energy-producing and defense wastes. The background papers prepared in support of this document contain additional information on the relevance of the research in the long term to energy-producing technologies. Detailed scientific plans and other research documents are available for high priority research areas, for example, in subsurface transport of organic chemicals and mixtures and in the microbiology of deep aquifers. 5 figs., 1 tab

  12. 75 FR 43944 - Membership of the Defense Logistics Agency (DLA) Senior Executive Service (SES) Performance...

    Science.gov (United States)

    2010-07-27

    ... CONTACT: Ms. Lisa Novajosky, SES Program Manager, DLA Human Resources (J-14), Defense Logistics Agency... DEPARTMENT OF DEFENSE Defense Logistics Agency Membership of the Defense Logistics Agency (DLA... management of the SES cadre. DATES: Effective Date: September 16, 2010. ADDRESSES: Defense Logistics Agency...

  13. USAHA MENURUNKAN PENGGUNAAN PESTISIDA KIMIA DENGAN PROGRAM PENGENDALIAN HAMA TERPADU (Efforts to Reduce Chemical Pesticides Use through Integrated Pest Management Program

    Directory of Open Access Journals (Sweden)

    Joko Mariyono

    2001-04-01

    Full Text Available ABSTRAK Pestisida kimia merupakan bahan beracun yang menyebabkan pencemaran lingkungan dan berbahaya bagi kesehatan manusia. Penggunaannya yang berlebihan telah menimbulkan biaya eksternal yang sangat tinggi. Sejak tahun 1989 Pemerintah Indonesia telah berusaha mengurangi penggunaan pestisida kimia melalui program Pengendalian Hama Terpadu (PHT Untuk mengetahui dampak program PHT, digunakan fungsi permintaan pestisida kimia. Analisis ini menggunakan data sekunder selama sembilan tahun yang diambil dari empat kabupaten wilayah Yogyakarta. Hasil analisis menunjukkan bahwa  dampak program PHT telah berhasil mengurangi penggunaan pestisida kimia pada padi dan kedelai. Penurunan penggunaan pestisida kimia disebabkan oleh kenaikan harga dan penyebaran teknologi PHT. Turunnya penggunaan pestisida kimia ini akan meningkatkan kualitas lingkungan dan kesehatan manusia karena tersedia bahan pangan yang residu pestisida kimianya rendah.   ABSTRACT Chemical pesticide is a poisonous agent that causes deterioration on environment quality and thereatens to human health. It causes considerable high externat cost. Sice 1989 the Government of Indonesia had removed chemical pesticide subsidy and introduced a new program called Integrated {est chemical pestidice use. The objectives of this research was to determine the impact of IPM Program on cemical pesticide use in rice and soybean cultivation. To determine the impact, ademand model of cemical pesticide was employed. Time series secondary data for nine years collected from related institutions in four revencies of Yogyakarta were utilized as the basic analysis. Results of the analysis indicated that chemical pesticide uses in rice and soybean cultivation have declined. The reduction of chemical pesticide use was caused by the increase of chemical pesticide price due to the discontinuation of chemical pesticide subsidy, and dissemination of IPM program. It implied that the

  14. Assessment of Accelerated Acquisition of Defense Programs

    Science.gov (United States)

    2016-09-01

    Quadrennial Defense Review explicitly called for doubling production rates of ISR UAVs, including Global Hawk. By 2009, Global Hawks had logged over 25,000...Honeywell (Formerly AlliedSignal) turboprop engine, compared to the Predator’s 115 hp (86 kW) piston engine. The power increase allows the Reaper...on basic requirements subsequently translated into costs at least double initial estimates and years of schedule slippage. In other words a classic

  15. Recommendations for sampling for prevention of hazards in civil defense. On analytics of chemical, biological and radioactive contaminations. Brief instruction for the CBRN (chemical, biological, radioactive, nuclear) sampling; Empfehlungen fuer die Probenahme zur Gefahrenabwehr im Bevoelkerungsschutz. Zur Analytik von chemischen, biologischen und radioaktiven Kontaminationen. Kurzanleitung fuer die CBRN-Probenahme

    Energy Technology Data Exchange (ETDEWEB)

    Bachmann, Udo; Biederbick, Walter; Derakshani, Nahid (and others)

    2010-07-01

    The recommendation for sampling for prevention of hazards in civil defense is describing the analytics of chemical, biological and radioactive contaminations and includes detail information on the sampling, protocol preparation and documentation procedures. The volume includes a separate brief instruction for the CBRN (chemical, biological, radioactive, nuclear) sampling.

  16. Study on chemical reactivity control of liquid sodium. Research program

    International Nuclear Information System (INIS)

    Saito, Jun-ichi; Ara, Kuniaki; Sugiyama, Ken-ichiro; Kitagawa, Hiroshi; Oka, Nobuki; Yoshioka, Naoki

    2007-01-01

    Liquid sodium has the excellent properties as coolant of the fast breeder reactor (FBR). On the other hand, it reacts high with water and oxygen. So an innovative technology to suppress the reactivity is desired. The purpose of this study is to control the chemical reactivity of liquid sodium by dispersing the nanometer-size metallic particles (we call them Nano-particles) into liquid sodium. We focus on the atomic interaction between Nano-particles and sodium atoms. And we try to apply it to suppress the chemical reactivity of liquid sodium. Liquid sodium dispersing Nano-particles is named 'Nano-fluid'. Research programs of this study are the Nano-particles production, the evaluation of reactivity suppression of liquid sodium and the feasibility study to FBR plant. In this paper, the research programs and status are described. The important factors for particle production were understood. In order to evaluate the chemical reactivity of Nano-fluid the research programs were planned. The feasibility of the application of Nano-fluid to the coolant of FBR plant was evaluated preliminarily from the viewpoint of design and operation. (author)

  17. SDI (Strategic Defense Initiative) Software Technology Program Plan

    Science.gov (United States)

    1987-06-01

    station control, and defense. c. Simulation Display Generator ( SDG ) [Patterson 83] I0 SDG supports the creation, display, modification, storage, and...34 Proceedings Trends and Applications 1981, IEEE, (May 28, 1981). [Parnas 86] Parnas, D.L., "When can Software be Trustworthy?" Keynote Address to Compass 󈨚

  18. The chemistry of antipredator defense by secondary compounds in neotropical lepidoptera: facts, perspectives and caveats

    OpenAIRE

    Trigo, José R.

    2000-01-01

    Chemical defense against predation in butterflies and moths has been studied since nineteenth century. A classical example is that of the larvae of the monarch butterfly Danaus plexippus, which feed on leaves of Asclepias curassavica (Asclepiadaceae), sequestering cardenolides. The adults are protected against predation by birds. Several other substances may be involved in chemical defense, such as iridoid glycosides, cyanogenic glycosides, glucosinolates, pyrrolizidine and tropane alkaloids,...

  19. The Defense Science Board 2001 Summer Study on Defense Science and Technology

    Science.gov (United States)

    2002-05-01

    HIT” The threat of biological weapons arises in part from a decades-old megatrend in the life sciences. New advances in molecular biology, genetics...99 The Technology Landscape Today.................................... 101 Biological Warfare Defense...planning and programming, today’s environment comprises a broader, more diffuse set of concerns: terrorism, biological warfare, regional tensions

  20. Materials evaluation programs at the Defense Waste Processing Facility

    International Nuclear Information System (INIS)

    Gee, J.T.; Iverson, D.C.; Bickford, D.F.

    1992-01-01

    The Savannah River Site (SRS) has been operating a nuclear fuel cycle since the 1950s to produce nuclear materials in support of the national defense effort. About 83 million gallons of high-level waste produced since operations began has been consolidated by evaporation into 33 million gallons at the waste tank farm. The Department of Energy authorized the construction of the Defense Waste Processing Facility (DWPF), the function of which is to immobilize the waste as a durable borosilicate glass contained in stainless steel canisters prior to the placement of the canisters in a federal repository. The DWPF is now mechanically complete and is undergoing commissioning and run-in activities. A brief description of the DWPF process is provided

  1. Who Pays for National Defense? Financing Defense Programs in the United States, 1947-2007

    Science.gov (United States)

    Heo, Uk; Bohte, John

    2012-01-01

    Past studies on military expenditures in the United States have primarily focused on the extent to which guns versus butter trade-offs are prevalent without examining this relationship in the context of how other fiscal policy tools are used to pay for defense. Using annual data from 1947-2007, this study examines the relative importance of…

  2. Recommendations for sampling for prevention of hazards in civil defense. On analytics of chemical, biological and radioactive contaminations. 2. ed.; Empfehlungen fuer die Probenahme zur Gefahrenabwehr im Bevoelkerungsschutz. Zur Analytik von chemischen, biologischen und radioaktiven Kontaminationen

    Energy Technology Data Exchange (ETDEWEB)

    Bachmann, Udo; Derakshani, Nahid; Drobig, Matthias; Koenig, Mario; Mentfewitz, Joachim; Prast, Hartmut; Uelpenich, Gerhard; Vidmayer, Marc; Wilbert, Stefan; Wolf, Manfred

    2016-07-01

    The recommendations for sampling for prevention of hazards in civil defense (analytics of chemical, biological and radioactive contaminations) cover the following topics: Requirements for sampling, description of the materials (chemical, biological and radioactive contaminated materials), decontamination, sample transport and protocol documents.

  3. Cybersecurity:The Road Ahead for Defense Acquisition

    Science.gov (United States)

    2016-06-01

    contested environment. Cybersecurity being treated as key “leader business ” is criti- cal to the overall cybersecurity posture of our DoD acquisi... Cybersecurity The Road Ahead for Defense Acquisition Steve Mills n Steve Monks Mills and Monks are professors of Program Management at the Defense...not only on adequate funding for leaps in technology but also on honing that technology to protect the capability against cybersecurity threats. The

  4. Probabilistic safety assessment in the chemical and nuclear industries

    CERN Document Server

    Fullwood, Ralph R

    2000-01-01

    Probabilistic Safety Analysis (PSA) determines the probability and consequences of accidents, hence, the risk. This subject concerns policy makers, regulators, designers, educators and engineers working to achieve maximum safety with operational efficiency. Risk is analyzed using methods for achieving reliability in the space program. The first major application was to the nuclear power industry, followed by applications to the chemical industry. It has also been applied to space, aviation, defense, ground, and water transportation. This book is unique in its treatment of chemical and nuclear risk. Problems are included at the end of many chapters, and answers are in the back of the book. Computer files are provided (via the internet), containing reliability data, a calculator that determines failure rate and uncertainty based on field experience, pipe break calculator, event tree calculator, FTAP and associated programs for fault tree analysis, and a units conversion code. It contains 540 references and many...

  5. Erosion/corrosion concerns in feed preparation systems at the Defense Waste Processing Facility

    International Nuclear Information System (INIS)

    Gee, J.T.; Chandler, C.T.; Daugherty, W.L.; Imrich, K.J.; Jenkins, C.F.

    1997-01-01

    The Savannah River Site (SRS) has been operating a nuclear fuel cycle since the 1950's to produce nuclear materials in support of the national defense effort. The Department of Energy authorized the construction of the Defense Waste Processing Facility (DWPF) to immobilize the high level radioactive waste resulting from these processes as a durable borosilicate glass. The DWPF, after having undergone extensive testing, has been approved for operations and is currently immobilizing radioactive waste. To ensure reliability of the DWPF remote canyon processing equipment, a materials evaluation program was performed prior to radioactive operations to determine to what extent erosion/corrosion would impact design life of equipment. The program consisted of performing pre-service baseline inspections on critical equipment and follow-up inspections after completion of DWPF cold chemical demonstration runs. Non-destructive examination (NDE) techniques were used to assess erosion/corrosion as well as evaluation of corrosion coupon racks. These results were used to arrive at predicted equipment life for selected feed preparation equipment. It was concluded with the exception of the coil and agitator for the slurry mix evaporator (SME), which are exposed to erosive glass frit particles, all of the equipment should meet its design life

  6. Do Training Programs Work? An Assessment of Pharmacists Activities in the Field of Chemical Dependency.

    Science.gov (United States)

    Brooks, Valerie G.; Brock, Tina Penick; Ahn, Jungeun

    2001-01-01

    Seeks to determine if pharmacists who attended a chemical dependency training program were performing more chemical dependency related activities. Results reveal that participants were more likely to perform the following activities: lecture to community groups about chemical dependency; participate in a pharmacists' recovery program; provide…

  7. Activation of chemical biological defense mechanisms and remission of vital oxidative injury by low dose radiation

    International Nuclear Information System (INIS)

    Yamaoka, K.; Nomura, T.; Kojima, S.

    2000-01-01

    Excessive active oxygen produced in vivo by various causes is toxic. Accumulation of oxidation injuries due to excessive active causes cell and tissue injuries, inducing various pathologic conditions such as aging and carcinogenesis. On the other hand, there are chemical defense mechanisms in the body that eliminate active oxygen or repair damaged molecules, defending against resultant injury. It is interesting reports that appropriate oxidation stress activate the chemical biological defense mechanisms. In this study, to elucidate these phenomena and its mechanism by low dose radiation, we studied on the below subjects. Activation of chemical biological defense mechanisms by low dose radiation: (1) The effects radiation on lipid peroxide (LPO) levels in the organs, membrane fluidity and the superoxide dismutase (SOD) activity were examined in rats and rabbits. Rats were irradiated with low dose X-ray over their entire bodies, and rabbits inhaled vaporized radon spring water, which primarily emitted α-ray. The following results were obtained. Unlike high dose X-ray, low dose X-ray and radon inhalation both reduced LPO levels and made the state of the SH-group on membrane-bound proteins closer to that of juvenile animals, although the sensitivity to radioactivity varied depending on the age of the animals and among different organs and tissues. The SOD activity was elevated, suggesting that low dose X-ray and radon both activate the host defensive function. Those changes were particularly marked in the organs related to immune functions of the animals which received low dose X-ray, while they were particularly marked in the brain after radon inhalation. It was also found that those changes continued for longer periods after low dose X-irradiation. (2) Since SOD is an enzyme that mediates the dismutation of O 2 - to H 2 O 2 , the question as to whether the resultant H 2 O 2 is further detoxicated into H 2 O and O 2 or not must still be evaluated. Hence, we studied

  8. Nano/micromotors for security/defense applications. A review

    Science.gov (United States)

    Singh, Virendra V.; Wang, Joseph

    2015-11-01

    The new capabilities of man-made micro/nanomotors open up considerable opportunities for diverse security and defense applications. This review highlights new micromotor-based strategies for enhanced security monitoring and detoxification of chemical and biological warfare agents (CBWA). The movement of receptor-functionalized nanomotors offers great potential for sensing and isolating target bio-threats from complex samples. New mobile reactive materials based on zeolite or activated carbon offer considerable promise for the accelerated removal of chemical warfare agents. A wide range of proof-of-concept motor-based approaches, including the detection and destruction of anthrax spores, `on-off' nerve-agent detection or effective neutralization of chemical warfare agents have thus been demonstrated. The propulsion of micromotors and their corresponding bubble tails impart significant mixing that greatly accelerates such detoxification processes. These nanomotors will thus empower sensing and destruction where stirring large quantities of decontaminating reagents and controlled mechanical agitation are impossible or undesired. New technological breakthroughs and greater sophistication of micro/nanoscale machines will lead to rapid translation of the micromotor research activity into practical defense applications, addressing the escalating threat of CBWA.

  9. Nuclear forensics-metrological basis for legal defensibility

    International Nuclear Information System (INIS)

    Leggitt, J.; Inn, K.; Goldberg, S.; Essex, R.; LaMont, S.; Chase, S.

    2009-01-01

    The admissibility of nuclear forensics measurements and opinions derived from them in US Federal and State courts are based on criteria established by the US Supreme Court in the case of Daubert v. Merrell Dow and the 2000 Amendment of Rule 702 of the Federal Rules of Evidence. These criteria are being addressed by new efforts that include the development of certified reference materials (CRMs) to provide the basis for analytical method development, optimization, calibration, validation, quality control, testing, readiness, and declaration of measurement uncertainties. Quality data is crucial for all stages of the program, from R and D, and database development, to actual casework. Weakness at any point in the program can propagate to reduce the confidence of final conclusions. The new certified reference materials will provide the necessary means to demonstrate a high level of metrological rigor for nuclear forensics evidence and will form a foundation for legally defensible nuclear chemical analysis. The CRMs will allow scientists to devise validated analytical methods, which can be corroborated by independent analytical laboratories. CRMs are required for ISO accreditation of many different analytical techniques which may be employed in the analysis of interdicted nuclear materials. (author)

  10. Defense waste management plan

    International Nuclear Information System (INIS)

    1983-06-01

    Defense high-level waste (HLW) and defense transuranic (TRU) waste are in interim storage at three sites, namely: at the Savannah River Plant, in South Carolina; at the Hanford Reservation, in Washington; and at the Idaho National Engineering Laboratory, in Idaho. Defense TRU waste is also in interim storage at the Oak Ridge National Laboratory, in Tennessee; at the Los Alamos National Laboratory, in New Mexico; and at the Nevada Test Site, in Nevada. (Figure E-2). This document describes a workable approach for the permanent disposal of high-level and transuranic waste from atomic energy defense activities. The plan does not address the disposal of suspect waste which has been conservatively considered to be high-level or transuranic waste but which can be shown to be low-level waste. This material will be processed and disposed of in accordance with low-level waste practices. The primary goal of this program is to utilize or dispose of high-level and transuranic waste routinely, safely, and effectively. This goal will include the disposal of the backlog of stored defense waste. A Reference Plan for each of the sites describes the sequence of steps leading to permanent disposal. No technological breakthroughs are required to implement the reference plan. Not all final decisions concerning the activities described in this document have been made. These decisions will depend on: completion of the National Environmental Policy Act process, authorization and appropriation of funds, agreements with states as appropriate, and in some cases, the results of pilot plant experiments and operational experience. The major elements of the reference plan for permanent disposal of defense high-level and transuranic waste are summarized

  11. Defense Agencies Initiative Increment 2 (DAI Inc 2)

    Science.gov (United States)

    2016-03-01

    module. In an ADM dated September 23, 2013, the MDA established Increment 2 as a MAIS program to include budget formulation; grants financial...2016 Major Automated Information System Annual Report Defense Agencies Initiative Increment 2 (DAI Inc 2) Defense Acquisition Management...President’s Budget RDT&E - Research, Development, Test, and Evaluation SAE - Service Acquisition Executive TBD - To Be Determined TY - Then

  12. Why even good defenses may be bad

    International Nuclear Information System (INIS)

    Glaser, C.L.

    1984-01-01

    The current debate over whether an effective ballistic missile defense (BMD) is technically feasible and whether it could be developed and deployed has left most of the advocacy up to those supporting a BMD program. The author emphasizes the issues beyond technical feasibility in his conclusion that assured destruction may still be preferable to perfect defense in terms of reducing the probability of nuclear war. After examining a number of possible scenarios involving the US and Soviet Union, the positions of allies, and the possibility of clandestine bombs, he sees no reason to expect that a defense system would be less vulnerable or have fewer uncertainties. 29 references

  13. Multiple Identified Neurons and Peripheral Nerves Innervating the Prothoracic Defense Glands in Stick Insects Reveal Evolutionary Conserved and Novel Elements of a Chemical Defense System

    Directory of Open Access Journals (Sweden)

    Johannes Strauß

    2017-11-01

    Full Text Available The defense glands in the dorsal prothorax are an important autapomorphic trait of stick insects (Phasmatodea. Here, we study the functional anatomy and neuronal innervation of the defense glands in Anisomorpha paromalus (Westwood, 1859 (Pseudophasmatinae, a species which sprays its defense secretions when disturbed or attacked. We use a neuroanatomical approach to identify the nerves innervating the gland muscles and the motoneurons with axons in the different nerves. The defense gland is innervated by nerves originating from two segments, the subesophageal ganglion (SOG, and the prothoracic ganglion. Axonal tracing confirms the gland innervation via the anterior subesophageal nerve, and two intersegmental nerves, the posterior subesophageal nerve, and the anterior prothoracic nerve. Axonal tracing of individual nerves reveals eight identified neuron types in the subesophageal or prothoracic ganglion. The strongest innervating nerve of the gland is the anterior subesophageal nerve, which also supplies dorsal longitudinal thorax muscles (neck muscles by separate nerve branches. Tracing of individual nerve branches reveals different sets of motoneurons innervating the defense gland (one ipsilateral and one contralateral subesophageal neuron or the neck muscle (ventral median neurons. The ipsilateral and contralateral subesophageal neurons have no homologs in related taxa like locusts and crickets, and thus evolved within stick insects with the differentiation of the defense glands. The overall innervation pattern suggests that the longitudinal gland muscles derived from dorsal longitudinal neck muscles. In sum, the innervating nerves for dorsal longitudinal muscles are conserved in stick insects, while the neuronal control system was specialized with conserved motoneurons for the persisting neck muscles, and evolutionarily novel subesophageal and prothoracic motoneurons innervating the defense gland.

  14. Technology for the long-term management of defense HLW at the Idaho Chemical Processing Plant

    International Nuclear Information System (INIS)

    Staples, B.A.; Berreth, J.R.; Knecht, D.A.

    1986-01-01

    The Defense Waste Management Plan of June 1983 includes a reference plan for the long-term management of Idaho Chemical Processing Plant (ICPP) high-level waste (HLW), with a goal of disposing of the annual output in 500 canisters a year by FY-2008. Based on the current vitrification technology, the ICPP base-glass case would produce 1700 canisters per year after FY-2007. Thus, to meet the DWMP goal processing steps including fuel dissolution, waste treatment, and waste immobilization are being studied as areas where potential modifications could result in HLW volume reductions for repository disposal. It has been demonstrated that ICPP calcined wastes can be densified by hot isostatic pressing to multiphase ceramic forms of high loading and density. Conversion of waste by hot isostatic pressing to these forms has the potential of reducing the annual ICPP waste production to volumes near those of the goal of the DWMP. This report summarizes the laboratory-scale information currently available on the development of these forms

  15. 75 FR 54524 - Defense Federal Acquisition Regulation Supplement; Acquisition Strategies To Ensure Competition...

    Science.gov (United States)

    2010-09-08

    ...., because the changes are to internal Government organization and operating procedures only. The rule... 48 CFR Part 207 Government procurement. Ynette R. Shelkin, Editor, Defense Acquisition Regulations... Life Cycle of Major Defense Acquisition Programs (DFARS Case 2009-D014) AGENCY: Defense Acquisition...

  16. 76 FR 11361 - Defense Federal Acquisition Regulation Supplement; Preservation of Tooling for Major Defense...

    Science.gov (United States)

    2011-03-02

    ... the ``preservation and storage of unique tooling associated with the production of hardware for a... agrees with the concept to sustain capability and supportability to the extent needed under major weapons... tooling associated with the production of hardware for a major defense acquisition program. DoD thinks...

  17. Defense radioactive waste management

    International Nuclear Information System (INIS)

    Hindman, T.B. Jr.

    1988-01-01

    The Office of Defense Programs (DP), U.S. Department of Energy, is responsible for the production of nuclear weapons and materials for national defense. Pursuant to this mission, DP operates a large industrial complex that employs over 60,000 people at various installations across the country. As a byproduct of their activities, these installations generate radioactive, hazardous, or mixed wastes that must be managed in a safe and cost-effective manner in compliance with all applicable Federal and STate environmental requirements. At the Federal level such requirements derive primarily from the Atomic Energy Act, the Resource Conservation and Recovery Act (RCRA), the comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and the Superfund Amendments and Reauthorization Act (SARA). Responsibility for DP activities in connection with the disposal of defense wastes is consolidated within the Office of Defense Waste and Transportation Management (DWTM). This paper discusses these activities which consist of five principal elements: the environmental restoration of inactive DP facilities and sites, the processing storage and disposal of wastes associated with ongoing operations at active DP facilities, research and development directed toward the long-term disposal of radioactive, hazardous, mixed wastes, technology development directly supporting regulatory compliance, and the development of policies, procedures, and technologies for assuring the safe transportation of radioactive and hazardous materials

  18. Defense Acquisition Reform, 19602009: An Elusive Goal

    Science.gov (United States)

    2011-10-31

    the seven largest economies of the world (United States, China, Japan, Germany, France, United Kingdom, and Italy ).11 Major weapon systems...the Federal Acquisition Regulation.96 95 Ibid., pp. 20, 21. 96 Joseph Ferrara , “DoD’s 5000 Documents: Evolution and Change in Defense Acquisition...Wayne Smith. How Much Is Enough: Shaping the Defense Program, 1961–1969. New York: Harper & Row, 1971. Ferrara , Joseph. “DoD’s 5000 Documents

  19. Risk assessment of DOE defense program packages in a beyond 10 CFR 71.73 transportation accident environment

    International Nuclear Information System (INIS)

    Sandquist, G.M.; Bennion, J.S.; Moore, J.E.

    1992-01-01

    A comprehensive program is being conducted by the DOE to determine the risks related to the domestic transportation of radioactive and hazardous materials associated with nuclear weapons. The program is designed to identify, quantify and manage potential risks to public health and safety including potential radiological and toxicological health consequences which may exceed the 10 CFR 71.73 transportation accident environment A major objective of this program being performed by the Lawrence Livermore National Laboratory (LLNL) and the University of Utah is to provide the DOE with the methodology and bases for evaluating highway transportation activities by DOE contractors. This paper describes the approach and the HITRA model which is based upon probabilistic risk assessment (PRA) methodology and route specific data associated with the proposed transportation activity. The model is capable of providing detailed, location and time specific data for assessing projected risks to public health and safety from DOE defense program materials shipments

  20. Human biomonitoring in civil defense; Humanbiomonitoring im Bevoelkerungsschutz

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, Michael; Schmiechen, Katharina [Universitaetsmedizin Goettingen (Germany). Arbeits-, Sozial- und Umweltmedizin

    2012-07-01

    The booklet on human biomonitoring (HBM) in civil defense covers the following issues within two sections: (1) general part: definition and importance of human biomonitoring; application in civil defense; practice in a CBRN (chemical, biological, radiation, nuclear) scenario; sampling following a CBRN assignment; HBM for antidote administration; peculiarities of sampling in case of biological agents; microbiological detection procedure; human biomonitoring of radioactive metal isotopes. (2) Special part: substance profiles; list of HBM laboratories; list of poison information centers; questionnaire for exposure assessment in case of dangerous substance accidents; agreement for human biomonitoring examination.

  1. Achieving RCRA compliance in DOE defense waste management operations

    International Nuclear Information System (INIS)

    Frankhauser, W.A.; Shepard, M.D.

    1989-01-01

    The U.S. Department of Energy (DOE) generates significant volumes of radioactive mixed waste (RMW) through its defense-related activities. Defense RMW is co-regulated by DOE and the U.S. Environmental Protection Agency/State agencies in accordance with requirements of the Resource Conservation and Recovery Act (RCRA) and the Atomic Energy Act (AEA). This paper highlights some of the problems encountered in co-regulation and discusses achievements of the defense waste management program in integrating RCRA requirements into RMW operations. Defense waste sites are planning facility modifications and major new construction projects to develop treatment, storage and disposal capacity for existing RMW inventories and projected needs

  2. High Molecular Weight Polymers in the New Chemicals Program

    Science.gov (United States)

    There are three categories or types of High Molecular Weight (HMW, 10,000 daltons) polymers typically reviewed by the New Chemicals Program: Soluble, insoluble, and water absorbing. Each of the three types are treated differently.

  3. THE PLANNING, PROGRAMING, BUDGETING SYSTEM AND ITS IMPLEMENTATION IN THE SERBIAN MINISTRY OF DEFENSE

    Directory of Open Access Journals (Sweden)

    Sasa RADUSKI

    2010-01-01

    Full Text Available The main purpose of introducing the PPBES to the Serbian Ministry of Defense and the Serbian Armed Forces is to provide a rational management of resources and to maintain and build capacity of the Ministry and the Serbian Armed Forces in order to achieve their goals, objectives and missions.Expected results of implementation of the PPBES are reflected in increasing the efficiency and rationalization of the defense planning to a higher level, ensuring compatibility with defense planning and budgeting system of the state and developing a foundation for the effective management of defense resources.

  4. The terrorist threat nuclear, radiological, biological, chemical - a medical approach

    International Nuclear Information System (INIS)

    Revel, M.C. de; Gourmelon, M.C.S.; Vidal, P.C.; Renaudeau, P.C.S.

    2005-01-01

    Since September 11, 2001, the fear of a large scale nuclear, biological and/or chemical terrorism is taken again into consideration at the highest level of national policies of risk prevention. The advent of international terrorism implies a cooperation between the military defense and the civil defense. The nuclear, radiological, biological and chemical (NRBC) experts of the health service of army and of civil defense will have to work together in case of major terror attack. This book presents this cooperation between civil and military experts in the NRBC domain: risk analysis, national defense plans, crisis management, syndromes and treatments. The different aspects linked with the use of nuclear, biological and chemical weapons are analyzed by the best experts from French medical and research institutes. All topics of each NRBC domain are approached: historical, basic, diagnostic, therapeutic and preventive. (J.S.)

  5. Science and defense 2003: the future on-board energies; Science et defense 2003: les futures energies embarquees

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    Since 1983, the DGA (delegation of armament) organizes the colloquium ''Science and defense'' in the domains of the scientific research and the defense. The 2003 colloquium took place in Paris on December 2 and 3 and concerns the future portable energies. This paper is a summary presentation of the presented topics: the needs and the developments for the portable energies, the state of the art of the mini and micro energy sources and their limitations, the energy materials which strongly provide energy by chemical transformation, the new energy sources of medium power, the environmental impacts. The budget devoted to these researches in 2002 by the DGA, are also presented. (A.L.B.)

  6. The MICA Case Conference Program at Tewksbury Hospital, Mass.: an integrated treatment model.

    Science.gov (United States)

    Clodfelter, Reynolds C; Albanese, Mark J; Baker, Gregg; Domoto, Katherine; Gui, Amy L; Khantzian, Edward J

    2003-01-01

    This report describes the MICA (Mentally Ill Chemically Abusing) Program at the Tewksbury Hospital campus in Tewksbury, Massachusetts. Several campus facilities collaborate in the MICA Program. Through Expert Case Conferences, principles of integrated psychosocial treatment with dual diagnosis patients are demonstrated. An expert clinician focuses on the interplay between psychological pain, characterological traits, defenses, and the patient's drug of choice. Patients who have participated in the program have reported positive experiences. The staff reported that the program has resulted in facility improvement in assessment and treatment of complex dual diagnosis patients.

  7. BALANCER: A Computer Program for Balancing Chemical Equations.

    Science.gov (United States)

    Jones, R. David; Schwab, A. Paul

    1989-01-01

    Describes the theory and operation of a computer program which was written to balance chemical equations. Software consists of a compiled file of 46K for use under MS-DOS 2.0 or later on IBM PC or compatible computers. Additional specifications of courseware and availability information are included. (Author/RT)

  8. Fiscal year 1987 program plan

    International Nuclear Information System (INIS)

    1986-12-01

    The Defense TRU Waste Program (DTWP) is the focal point for the Department of Energy in national planning, integration, operation, and technical development for TRU waste management. The scope of this program extends from the point of TRU waste generation through delivery to a permanent repository. The TRU program maintains a close interface with repository development to ensure program compatibility and coordination. The defense TRU program does not directly address commercial activities that generate TRU waste. Instead, it is concerned with providing alternatives to manage existing and future defense TRU wastes. The FY 87 Program Plan is consistent with the Defense TRU Waste Program goals and objectives stated in the Defense Transuranic Waste Program Strategy Document, January 1984. The roles of participants, the responsibilities and authorities for Operations, and Research ampersand Development (R ampersand D), the organizational interfaces and communication channels for R ampersand D and the establishment of procedures for planning, reporting, and budgeting of Operations and R ampersand D activities meet requirements stated in the Technical Management Plan for the Transuranic Waste Management Program. Detailed budget planning (i.e., programmatic funding and capital equipment) is presented for FY 87; outyear budget projections are presented for future years

  9. Second line of defense program overview LA-UR-00-5161

    International Nuclear Information System (INIS)

    Knepper, P.L.; Martin, D.D.W.

    2001-01-01

    Full text: The illicit trafficking of nuclear material is a major concern for non-proliferation and global stability. The nuclear Material Protection, Control and Accounting (MPC and A) program provides the first line of defense in protecting nuclear materials within Russia by upgrading safeguards and security measures at Russian nuclear facilities. Second Line of Defense (SLD) is a cooperative program between the Russian Federation State Customs Committee (RF SCC) and the United States Department of Energy (US DOE) to minimize illicit trafficking of restricted nuclear materials through Russian border control points. This partnership was solidified with the signing of a protocol between DOE and the RF SCC in June 1998. The relationship will soon be formalized in a Memorandum of Understanding that will outline the working relationships and commitments to successful implementation of the SLD Program. The Russians first acknowledged the threat of nuclear smuggling at a Nuclear Safety Summit in Moscow in April 1996. Nikolai Kravehenko, head of the Regional Information and Technical Customs Department of the RF SCC, subsequently stated in a July 1998 interview, 'In order to stop trafficking and illegal shipment to other countries we [also] have to tighten security at the facilities and equip our borders with reliable technology.' At the September 1998 U.S.-Russia Presidential Summit, the then Chairman of the RF SCC, Valery Draganov, highlighted the illicit trafficking challenge confronting Russia and requested U.S. assistance. Since 1991, a myriad of cases associated with the diversion and recovery of nuclear materials appear to be linked to the FSU. In the majority of cases, the material's origin was attributed to Russia. With more than 20,000 km of border contiguous to fourteen other countries, and more than 350 customs and border sites, addressing the threat posed by nuclear smuggling in Russia is not only an urgent but also an expansive problem requiring joint U

  10. 78 FR 63462 - Information Collection Requirement; Defense Federal Acquisition Regulation Supplement...

    Science.gov (United States)

    2013-10-24

    ... Relating to Organizational Conflict of Interest-Major Defense Acquisition Program; OMB Control Number 0704...] Information Collection Requirement; Defense Federal Acquisition Regulation Supplement; Organizational Conflict... submit comments, identified by OMB Control Number 0704-0477, using any of the following methods: [cir...

  11. Appropriate Programs for Foreign Students in U.S. Chemical Engineering Curricula.

    Science.gov (United States)

    Findley, M. E.

    Chemical engineers in developing countries may need abilities in a number of diverse areas including management, planning, chemistry, equipment, processes, politics, and improvisation. Chemical engineering programs for foreign students can be arranged by informed advisers with student input for inclusion of some of these areas in addition to…

  12. 2006 Chemical Biological Individual Protection (CBIP) Conference and Exhibition

    Science.gov (United States)

    2006-03-09

    Requirements Office (JRO), MAJ W. Scott Smedley , Joint Requirements Office for Chemical, Biological, Radiological, and Nuclear Defense JPEO...Decker Director of Engineering 410-436-5600 www.ecbc.army.mil Gabe Patricio, JPEO 703 681-0808 Robert Wattenbarger, JPMOIP 703 432-3198 Canadian CBRN...UNCLASSIFIED Joint Requirements Office for Chemical, Biological, and Nuclear Defense MAJ W. Scott Smedley 8 March 2006 Individual Protection Conference

  13. Pregnant Employee Protection Program in a Large Chemical Company.

    Science.gov (United States)

    Frey, Gunild; Schuster, Michael; Oberlinner, Christoph; Queier-Wahrendorf, Annette; Lang, Stefan; Yong, Mei

    2015-09-01

    To assess whether a structured employee protection program for pregnant workers at a chemical company has an impact on pregnancy outcomes. Reported pregnancies (n = 1402) between 2003 and 2010 and their outcomes were documented using questionnaires at the time of pregnancy report, end of pregnancy, and 1 year later. Potential maternal exposures were assessed using job histories, workplace inspections, and questionnaires. Participation was 86% overall and was consistently high across subgroups.Pregnancy losses (10.9%), pregnancy complications, and preterm births (8.1%) were in agreement with rates in the general population and were independent of type of work and maternal exposure category. Pregnancy complication rates in this chemical company are not statistically elevated than that in the general population, as suggested in a previous study. The protection program may play a role in preventing complications that may have occurred.

  14. 75 FR 33752 - Defense Federal Acquisition Regulation Supplement; Organizational Conflicts of Interest in Major...

    Science.gov (United States)

    2010-06-15

    ... Conflicts of Interest in Major Defense Acquisition Programs AGENCY: Defense Acquisition Regulations System... extended an additional 30 days to provide additional time for interested parties to review the proposed... interested parties to review the proposed DFARS changes. Ynette R. Shelkin, Editor, Defense Acquisition...

  15. Assuring Condition and Inventory Accountability of Chemical Protective Suits

    National Research Council Canada - National Science Library

    2000-01-01

    .... As part of the Defense Logistics Agency's efforts to consolidate depot operations and improve inventory accuracy, chemical protective suits were transferred to the Defense Depot, Albany, Georgia, during FY 1991.

  16. Multiyear Procurement (MYP) and Block Buy Contracting in Defense Acquisition: Background and Issues for Congress

    Science.gov (United States)

    2016-05-27

    core aviation program and is approved for full- rate production through the future years defense program. If the proposal is approved, the Army buy ...Multiyear Procurement (MYP) and Block Buy Contracting in Defense Acquisition: Background and Issues for Congress Ronald O’Rourke Specialist...

  17. Iran the aerial defense facing a preventive attack against the nuclear sites; Iran la defense aerienne face a une attaque preventive contre ses sites nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Gruselle, B.; Payre, G

    2006-01-15

    In the context of the nuclear uranium enrichment program development facing the international opinion, the author discusses the Iran policy of implementing a defense against an aerial attack. Even with the modernization of its anti-aerial defense, the Iran will cannot support an aerial american campaign, precise and long. (A.L.B.)

  18. Defense Business Board

    Science.gov (United States)

    Skip to main content (Press Enter). Toggle navigation Defense Business Board Search Search Defense Business Board: Search Search Defense Business Board: Search Defense Business Board Business Excellence in Defense of the Nation Defense Business Board Home Charter Members Meetings Studies Contact Us The Defense

  19. Risk communications and the Chemical Stockpile Emergency-Planning Program

    Energy Technology Data Exchange (ETDEWEB)

    Vogt, B.M.; Sorensen, J.H.

    1994-09-01

    The CSEPP (Chemical Stockpile Emergency Preparedness Program) was created to improve emergency planning and response capabilities at the eight sites around the country that store chemical weapons. These weapons are scheduled to be destroyed in the near future. In preparation of the Draft Programmatic Environmental Impact Statement (DPEIS) for the Chemical Stockpile Disposal Program (CSDP), it was proposed that the Army mitigate accidents through an enhanced community emergency preparedness program at the eight storage sites. In 1986, the Army initiated the development of an Emergency Response Concept Plan (ERCP) for the CSDP, one of 12 technical support studies conducted during preparation of the Final Programmatic Environmental Impact Statement (FPEIS). The purpose of this document is to provide a fairly comprehensive source book on risk, risk management, risk communication research and recommended risk communication practices. It does not merely summarize each publication in the risk communication literature, but attempts to synthesize them along the lines of a set of organizing principles. Furthermore, it is not intended to duplicate other guidance manuals (such as Covello et al.`s manual on risk comparison). The source book was developed for the CSEPP in support of the training module on risk communications. Although the examples provided are specific to CSEPP, its use goes beyond that of CSEPP as the findings apply to a broad spectrum of risk communication topics. While the emphasis is on communication in emergency preparedness and response specific to the CSEPP, the materials cover other non-emergency communication settings. 329 refs.

  20. Low Level Chemical Toxicity: Relevance to Chemical Agent Defense

    Science.gov (United States)

    2005-07-01

    or confirm a diagnosis of chemical sensitivity and suggest novel approaches in managing this malady. Project 4: Studies of gene expression...Lindberg I, Ugleholdt R, Holst J & Steiner DF 2002b Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing...2004;1:32- 34. [10] Diederich S,Eckmanns,T,Exner,P,Al-Saadi,N,Bahr,V,Oelkers,W. Differential diagnosis of polyuric/polydipsic syndromes with the aid

  1. Integrating the commercial and defense high level waste programs - A utility perspective

    International Nuclear Information System (INIS)

    Tomonto, J.R.

    1986-01-01

    The Nuclear Waste Policy Act of 1982 provided that disposal of high-level wastes resulting from defense activities be included in the authorized repository unless the President determined that separate facilities are required. President Reagan approved commingling of defense and civilian wastes on April 30, 1985. The impacts of this decision on the repository schedule, civilian spent fuel acceptance rates, and cost sharing are reviewed and recommendations for resolving these issues are presented

  2. Defense by-products production and utilization program: noble metal recovery screening experiments

    International Nuclear Information System (INIS)

    Hazelton, R.F.; Jensen, G.A.; Raney, P.J.

    1986-03-01

    Isotopes of the platinum metals (rutheium, rhodium, and palladium) are produced during uranium fuel fission in nuclear reactors. The strategic values of these noble metals warrant considering their recovery from spent fuel should the spent fuel be processed after reactor discharge. A program to evaluate methods for ruthenium, rhodium, and palladium recovery from spent fuel reprocessing liquids was conducted at Pacific Northwest Laboratory (PNL). The purpose of the work reported in this docuent was to evaluate several recovery processes revealed in the patent and technical literature. Beaker-scale screening tests were initiated for three potential recovery processes: precipitation during sugar denitration of nitric acid reprocessing solutions after plutonium-uranium solvent extraction, adsorption using nobe metal selective chelates on active carbon, and reduction forming solid noble metal deposits on an amine-borane reductive resin. Simulated reprocessing plant solutions representing typical nitric acid liquids from defense (PUREX) or commercial fuel reprocessing facilities were formulated and used for evaluation of the three processes. 9 refs., 3 figs., 9 tabs

  3. Chemical Exposure Assessment Program at Los Alamos National Laboratory: A risk based approach

    International Nuclear Information System (INIS)

    Stephenson, D.J.

    1996-01-01

    The University of California Contract And DOE Order 5480.10 require that Los Alamos National Laboratory (LANL) perform health hazard assessments/inventories of all employee workplaces. In response to this LANL has developed the Chemical Exposure Assessment Program. This program provides a systematic risk-based approach to anticipation, recognition, evaluation and control of chemical workplace exposures. Program implementation focuses resources on exposures with the highest risks for causing adverse health effects. Implementation guidance includes procedures for basic characterization, qualitative risk assessment, quantitative validation, and recommendations and reevaluation. Each component of the program is described. It is shown how a systematic method of assessment improves documentation, retrieval, and use of generated exposure information

  4. Conservation and divergence of chemical defense system in the tunicate Oikopleura dioica revealed by genome wide response to two xenobiotics

    Directory of Open Access Journals (Sweden)

    Yadetie Fekadu

    2012-02-01

    Full Text Available Abstract Background Animals have developed extensive mechanisms of response to xenobiotic chemical attacks. Although recent genome surveys have suggested a broad conservation of the chemical defensome across metazoans, global gene expression responses to xenobiotics have not been well investigated in most invertebrates. Here, we performed genome survey for key defensome genes in Oikopleura dioica genome, and explored genome-wide gene expression using high density tiling arrays with over 2 million probes, in response to two model xenobiotic chemicals - the carcinogenic polycyclic aromatic hydrocarbon benzo[a]pyrene (BaP the pharmaceutical compound Clofibrate (Clo. Results Oikopleura genome surveys for key genes of the chemical defensome suggested a reduced repertoire. Not more than 23 cytochrome P450 (CYP genes could be identified, and neither CYP1 family genes nor their transcriptional activator AhR was detected. These two genes were present in deuterostome ancestors. As in vertebrates, the genotoxic compound BaP induced xenobiotic biotransformation and oxidative stress responsive genes. Notable exceptions were genes of the aryl hydrocarbon receptor (AhR signaling pathway. Clo also affected the expression of many biotransformation genes and markedly repressed genes involved in energy metabolism and muscle contraction pathways. Conclusions Oikopleura has the smallest number of CYP genes among sequenced animal genomes and lacks the AhR signaling pathway. However it appears to have basic xenobiotic inducible biotransformation genes such as a conserved genotoxic stress response gene set. Our genome survey and expression study does not support a role of AhR signaling pathway in the chemical defense of metazoans prior to the emergence of vertebrates.

  5. Status summary of chemical processing development in plutonium-238 supply program

    Energy Technology Data Exchange (ETDEWEB)

    Collins, Emory D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Benker, Dennis [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wham, Robert M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); DePaoli, David W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Delmau, Laetitia Helene [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Sherman, Steven R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-10-01

    This document summarizes the status of development of chemical processing in the Plutonium-238 Supply Program (PSP) near the end of Demonstration 1. The objective of the PSP is “to develop, demonstrate, and document a production process that meets program objectives and to prepare for its operation” (Frazier et al. 2016). Success in the effort includes establishing capability using the current infrastructure to produce Np targets for irradiation in Department of Energy research reactors, chemically processing the irradiated targets to separate and purify the produced Pu and transferring the PuO2 product to Los Alamos National Laboratory (LANL) at an average rate of 1.5 kg/y.

  6. Quadrennial Defense Review Report

    Science.gov (United States)

    2010-02-01

    medicine , and computer network operations. While we continue to employ a mix of programs and incentives to recruit quality personnel, we are also...Lithuania* Singapore Australia Finland Luxembourg* Slovakia* Austria France* Macedonia Slovenia* Azerbaijan Georgia Montenegro Spain* Belgium...20,000 positions by 2015. We will continue to significantly enhance Secretary of Defense Robert M. Gates meets with plant workers during a tour of an

  7. Nevada test site defense waste acceptance criteria, certification, and transfer requirements

    International Nuclear Information System (INIS)

    1988-10-01

    The Nevada Test Site (NTS) Defense Waste Acceptance Criteria, Certification and Transfer Requirements establishes procedures and criteria for safe transfer, disposal, and storage of defense transuranic, low-level, and mixed waste at the NTS. Included are an overview of the NTS defense waste management program; the NTS waste acceptance criteria for transuranic, low-level, and mixed wastes; waste certification requirements and guidance; application to submit waste; and requirements for waste transfer and receipt. 5 figs., 16 tabs

  8. Mixed waste chemical compatibility: A testing program for plastic packaging components

    International Nuclear Information System (INIS)

    Nigrey, P.J.

    1995-01-01

    The purpose of hazardous and radioactive materials packaging is to enable these materials to be transported without posing a threat to the health or property of the general public. To achieve this aim, regulations in the United States have been written establishing general design requirements for such packagings. While no regulations have been written specifically for mixed waste packaging, regulations for the constituents of mixed wastes, i.e., hazardous and radioactive substances, have been codified by the US Department of Transportation (DOT, 49 CFR 173) and the US Nuclear Regulatory Commission (NRC, 10 CFR 71). The design requirements for both hazardous [49 CFR 173.24 (e)(1)] and radioactive [49 CFR 173.412 (g)] materials packaging specify packaging compatibility, i.e., that the materials of the packaging at sign d any contents be chemically compatible with each other. Furthermore, Type A [49 CFR 173.412 (g)] and Type B (10 CFR 71.43) packaging design requirements stipulate that there be no significant chemical, galvanic, or other reaction between the materials and contents of the package. Based on these requirements, a Chemical Compatibility Testing Program was developed in the Transportation Systems Department at Sandia National Laboratories (SNL). The program attempts to assure any regulatory body that the issue of packaging material compatibility towards hazardous and radioactive materials has been addressed. This program has been described in considerable detail in an internal SNL document, the Chemical Compatibility Test Plan ampersand Procedure Report (Nigrey 1993)

  9. 75 FR 64710 - Availability of the Fiscal Year 2009 Department of Defense Services Contracts Inventory

    Science.gov (United States)

    2010-10-20

    ... DEPARTMENT OF DEFENSE Office of the Secretary Availability of the Fiscal Year 2009 Department of... National Defense Authorization Act for Fiscal Year 2008 (NDAA 08) section 807, the Office of the Director, Defense Procurement and Acquisition Policy, Office of Program Acquisition and Strategic Sourcing (DPAP...

  10. The Department of Defense’s Second Chasm in RFID-UID Technology Adoption

    Science.gov (United States)

    2007-12-01

    Lenders Program DFAR Defense Financial Accounting Regulation DoD Department of Defense DoDSIG Department of Defense Suppliers Information Guide EFT ...through electronic funds transfer ( EFT ). Additionally, CCR shares the data with federal government procurement and electronic business systems. (CCR...government contracting procedures. Additionally, the small business contractors can also tap into SBA resources to find out the latest news on

  11. Federal agencies active in chemical industry-related research and development

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-29

    The Energy Policy Act of 1992 calls for a program to further the commercialization of renewable energy and energy efficient technologies for the industrial sector.. The primary objective of the Office of Industrial Technologies Chemical Industry Team is to work in partnership with the US chemical industry to maximize economic, energy, and environmental benefits through research and development of innovative technologies. This document was developed to inventory organizations within the federal government on current chemical industry-related research and development. While an amount of funding or number of projects specifically relating to chemical industry research and development was not defined in all organizations, identified were about 60 distinct organizations representing 7 cabinet-level departments and 4 independent agencies, with research efforts exceeding $3.5 billion in fiscal year 1995. Effort were found to range from less than $500 thousand per year at the Departments of Agriculture and the Interior to over $100 million per year at the Departments of Commerce, Defense, Energy, and Health and Human Services and the National Aeronautics and Space Administration. The total number of projects in these programs exceeded 10,000. This document is complete to the extent that agencies volunteered information. Additions, corrections, and changes are encouraged and will be incorporated in future revisions.

  12. CrossTalk: The Journal of Defense Software Engineering. Volume 26, Number 4

    Science.gov (United States)

    2013-07-01

    to 30 pound laptops were about as “portable” as comput- ers could be. Back in the 1960s, when Star Trek first debuted, Star Fleet ensigns walked...have accessible to me almost all recorded history. In the 1960s, when Star Trek had tablets disguised as PADDs, and cell phones and Bluetooth...handle the development at a small fraction of the average defense program cost. The history of defense and NASA programs offers plenty of examples of

  13. The National Guard Ballistic Missile Defense Mission minutemen at the Orgital Plane

    OpenAIRE

    Trenary, Ralph Hiram

    2004-01-01

    Approved for public release; distribution is unlimited This thesis examines the decision to assign the Ballistic Missile Defense mission to units of the Colorado and Alaska National Guard. The history of the Nike Ajax, Nike Hercules, Sentinel and Safeguard programs are examined to identify the origins of support for this decision. First-hand sources provide evidence that the National Guard performance in the Nike air defense program is a record of parity and some superiority to equivalent ...

  14. Four years of international counter proliferation training: The U.S. Department of Defense's experience

    International Nuclear Information System (INIS)

    Strauss, H.J.

    2001-01-01

    Full text: Over the last four years, the U.S. Department of Defense has engaged 17 countries in the former Soviet Union, Eastern/Central Europe, and the Baltic states in two counterproliferation initiatives, i.e., the DOD/FBI and the DOD/U.S. Customs Service Counterproliferation Programs. These activities are designed to train and equip border security and law enforcement personnel to prevent, deter, and investigate incidents related to weapons of mass destruction, as well as the trafficking in chemical, nuclear, and biological weapons materials and technologies. Though these programs have begun to produce tangible successes, some recipient countries have failed to demonstrate an earnest commitment to program goals. The U.S. DOD has fielded varied training courses in the region, together with associated WMD detection equipment. In spite of demands by the political leadership in many of the engaged countries, the most successful training has proven to be the more basic rather than the advanced training. Similarly, the real equipment needs prove to be for low rather than high technology. The presentation will explore the systemic, political/military, and geographic factors contributing to this result. The U.S. Department of Defense will continue to engage participating nations in these international counterproliferation programs, and will continue to respond positively to assistance requests based on recipient country needs and honest commitment. Still there remain numerous opportunities for other donor states and international agencies to make positive contributions in the counterproliferation arena. Only with increased donor state commitment - fiscal, programmatic, and personnel - together with full donor state coordination, can international proliferation and trafficking problems be effectively deterred and resolved. (author)

  15. 32 CFR 634.5 - Program objectives.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Program objectives. 634.5 Section 634.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Introduction § 634.5 Program objectives. (a) The objectives of motor vehicle traffic...

  16. Fertilization Changes Chemical Defense in Needles of Mature Norway Spruce (Picea abies

    Directory of Open Access Journals (Sweden)

    Line Nybakken

    2018-06-01

    Full Text Available Nitrogen availability limits growth in most boreal forests. However, parts of the boreal zone receive significant levels of nitrogen deposition. At the same time, forests are fertilized to increase volume growth and carbon sequestration. No matter the source, increasing nitrogen in the boreal forest ecosystem will influence the resource situation for its primary producers, the plants, with possible implications for their defensive chemistry. In general, fertilization reduces phenolic compound concentrations in trees, but existing evidence mainly comes from studies on young plants. Given the role of the phenolic compounds in protection against herbivores and other forest pests, it is important to know if phenolics are reduced with fertilization also in mature trees. The evergreen Norway spruce is long-lived, and it is reasonable that defensive strategies could change from the juvenile to the reproductive and mature phases. In addition, as the needles are kept for several years, defense could also change with needle age. We sampled current and previous year needles from an N fertilization experiment in a Norway spruce forest landscape in south-central Norway to which N had been added annually for 13 years. We analyzed total nitrogen (N and carbon (C, as well as low-molecular phenolics and condensed tannins. Needles from fertilized trees had higher N than those from controls plots, and fertilization decreased concentrations of many flavonoids, as well as condensed tannins in current year needles. In previous year needles, some stilbenes and condensed tannins were higher in fertilized trees. In control trees, the total phenolic concentration was almost five times as high in previous year needles compared with those from the current year, and there were great compositional differences. Previous year needles contained highest concentrations of acetophenone and stilbenes, while in the current year needles the flavonoids, and especially coumaroyl

  17. Defense AT&L (Volume 36, Number 3, May-June 2007)

    Science.gov (United States)

    2007-06-01

    recruit from the heritage community; their recruits are known by their MOS [Military Occupational Specialty] “09 Limas ”—es- sentially interpreters...Defense AT&L: May-June 2007 Acquisition & Logistics Excellence Defense AT&L: May-June 2007 86 Acquisition & Logistics Excellence at Huntington Beach , Calif...programs in endangered species protection, historic preservation, waste reduction, environmental cleanup, and pollution prevention. Installation

  18. 32 CFR 636.2 - Program objectives.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Program objectives. 636.2 Section 636.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION (SPECIFIC INSTALLATIONS) Fort Stewart, Georgia § 636.2 Program objectives. In addition to the...

  19. Technology Commercialization Program 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-01

    This reference compilation describes the Technology Commercialization Program of the Department of Energy, Defense Programs. The compilation consists of two sections. Section 1, Plans and Procedures, describes the plans and procedures of the Defense Programs Technology Commercialization Program. The second section, Legislation and Policy, identifies legislation and policy related to the Program. The procedures for implementing statutory and regulatory requirements are evolving with time. This document will be periodically updated to reflect changes and new material.

  20. Defensive repertoire of Drosophila larvae in response to toxic fungi

    NARCIS (Netherlands)

    Trienens, Monika; Kraaijeveld, Ken; Wertheim, Bregje

    2017-01-01

    Chemical warfare including insecticidal secondary metabolites is a well-known strategy for environmental microbes to monopolize a food source. Insects in turn have evolved behavioural and physiological defences to eradicate or neutralize the harmful microorganisms. We studied the defensive

  1. The Commonly Used Bactericide Bismerthiazol Promotes Rice Defenses against Herbivores

    OpenAIRE

    Pengyong Zhou; Xiaochang Mo; Wanwan Wang; Xia Chen; Yonggen Lou

    2018-01-01

    Chemical elicitors that enhance plant resistance to pathogens have been extensively studied, however, chemical elicitors that induce plant defenses against insect pests have received little attention. Here, we found that the exogenous application of a commonly used bactericide, bismerthiazol, on rice induced the biosynthesis of constitutive and/or elicited jasmonic acid (JA), jasmonoyl-isoleucine conjugate (JA-Ile), ethylene and H2O2 but not salicylic acid. These activated signaling pathways ...

  2. FY10 Defense Environmental Programs Annual Report to Congress

    Science.gov (United States)

    2011-07-01

    7,412- 2019  AIR FORCE ALPENA COUNTY REGIONAL AIRPORT / MI557282890300 17 2 $6,363 $0 $862 $1,9462012 2018  FORMERLY USED DEFENSE SITES ASH FIELD...Through FY10 ($000) IRP MMRPMMRPIRP Michigan ALPENA AAF / MI59799F231100 $001 $23 ALPENA NGTR / MI59799F228900 $610 $0 ANN ARBOR NGTR / MI59799F228800

  3. Standing Up a Narcotic Confirmation Laboratory for the Russian Federation Ministry of Defense Nuclear Personnel Reliability Program

    International Nuclear Information System (INIS)

    Lukyanenko, Victor; Eisele, Gerhard R.; Coates, Cameron W.

    2010-01-01

    Through a cooperative effort between the U. S. Department of Energy and the Russian Federation (RF) Ministry of Defense (MOD) a Personnel Reliability Program (PRP) for the nuclear handlers within the RF MOD has been implemented. A key element in the RF MOD PRP is the detection and confirmation of narcotic use in subject military and civilian personnel. This paper describes the process of narcotics screening and testing in the RF MOD and explains the confirmation process once screening has shown a positive result. Issues of laboratory certification, employee certification, employee training, sample chain-of-custody, and equipment needs will be addressed.

  4. Advanced thermal management technologies for defense electronics

    Science.gov (United States)

    Bloschock, Kristen P.; Bar-Cohen, Avram

    2012-05-01

    Thermal management technology plays a key role in the continuing miniaturization, performance improvements, and higher reliability of electronic systems. For the past decade, and particularly, the past 4 years, the Defense Advanced Research Projects Agency (DARPA) has aggressively pursued the application of micro- and nano-technology to reduce or remove thermal constraints on the performance of defense electronic systems. The DARPA Thermal Management Technologies (TMT) portfolio is comprised of five technical thrust areas: Thermal Ground Plane (TGP), Microtechnologies for Air-Cooled Exchangers (MACE), NanoThermal Interfaces (NTI), Active Cooling Modules (ACM), and Near Junction Thermal Transport (NJTT). An overview of the TMT program will be presented with emphasis on the goals and status of these efforts relative to the current State-of-the-Art. The presentation will close with future challenges and opportunities in the thermal management of defense electronics.

  5. Defense Logistics: A Completed Comprehensive Strategy is Needed to Guide DOD’s In-Transit Visibility Efforts

    Science.gov (United States)

    2013-02-01

    Defense Logistics List of Abbreviations aRFID active radio frequency identification DOD Department of Defense RFID...The Navy and the Air Force each have their own Active Radio Frequency Identification ( aRFID ) Migration Program. These two programs are included...with the aRFID Program and the aRFID Infrastructure, respectively and are therefore not listed in the table. Appendix III: Comments from the

  6. Different rates of defense evolution and niche preferences in clonal and nonclonal milkweeds (Asclepias spp.).

    Science.gov (United States)

    Pellissier, Loïc; Litsios, Glenn; Fishbein, Mark; Salamin, Nicolas; Agrawal, Anurag A; Rasmann, Sergio

    2016-02-01

    Given the dual role of many plant traits to tolerate both herbivore attack and abiotic stress, the climatic niche of a species should be integrated into the study of plant defense strategies. Here we investigate the impact of plant reproductive strategy and components of species' climatic niche on the rate of chemical defense evolution in the milkweeds using a common garden experiment of 49 species. We found that across Asclepias species, clonal reproduction repeatedly evolved in lower temperature conditions, in species generally producing low concentrations of a toxic defense (cardenolides). Additionally, we found that rates of cardenolide evolution were lower for clonal than for nonclonal species. We thus conclude that because the clonal strategy is based on survival, long generation times, and is associated with tolerance of herbivory, it may be an alternative to toxicity in colder ecosystems. Taken together, these results indicate that the rate of chemical defense evolution is influenced by the intersection of life-history strategy and climatic niches into which plants radiate. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

  7. Physical characteristics of calcium oxalate crystals as determinants in structural defense against chewing insects in Medicago truncatula

    Science.gov (United States)

    In addition to the numerous chemical defenses that plants employ to fend off insect herbivores, simple structural components can also play important roles in effective protection. Our investigations have shown that plant crystals of calcium oxalate can function in insect defense. The isolation of ca...

  8. Independent technical review of Savannah River Site Defense Waste Processing Facility technical issues

    International Nuclear Information System (INIS)

    1992-07-01

    The Savannah River Site (SRS) Defense Waste Processing Facility (DWPF) will vitrify high-level radioactive waste that is presently stored as liquid, salt-cake, and sludge in 51 waste-storage tanks. Construction of the DWPF began in 1984, and the Westinghouse Savannah Company (WSRC) considers the plant to be 100% turned over from construction and 91% complete. Cold-chemical runs are scheduled to begin in November 1992, and hot start up is projected for June 1994. It is estimated that the plant lifetime must exceed 15 years to complete the vitrification of the current, high-level tank waste. In a memo to the Assistant Secretary for Defense Programs (DP-1), the Assistant Secretary for Environmental Restoration and Waste management (EM-1) established the need for an Independent Technical Review (ITR), or the Red Team, to ''review process technology issues preventing start up of the DWPF.'' This report documents the findings of an Independent Technical Review (ITR) conducted by the Department of Energy (DOE), Office of Environmental Restoration and Waste Management (EM), at the request of the Assistant Secretary for Environmental Restoration and Waste Management, of specified aspects of Defense Waste Process Facility (DWPF) process technology. Information for the assessment was drawn from documents provided to the ITR Team by the Westinghouse Savannah River Company (WSRC), and presentations, discussions, interviews, and tours held at the Savannah River Site (SRS) during the weeks of February and March 9, 1992

  9. Operate A Chemical Surety Program And Studies Supporting The Medical Chemical Defense Research Program

    Science.gov (United States)

    2010-05-01

    Draize scoring, reflectance colorimetry , evaporimetry, and infrared thermography. Histopathologic evaluation of skin collected at 48 h post-exposure...lesion size measurements, modified Draize Scoring, and non-invasive bioengineering techniques, i.e. reflectance colorimetry , infrared imagery, and...modified Draize scoring, reflectance colorimetry , evaporimetry, and infrared thermography. Histopathologic evaluation of skin collected at 48 h post

  10. Twelfth symposium on biotechnology for fuels and chemicals: Program and abstracts

    International Nuclear Information System (INIS)

    Scheitlin, F.M.

    1990-01-01

    This report is the program and abstracts of the twelfth symposium on biotechnology for fuels and chemicals, held on May 7--11, 1990, at Gatlinburg, Tennessee. The symposium, sponsored by the Department of Energy, Oak Ridge National Laboratory, Solar Energy Research Institute, Badger Engineers, Inc., Gas Research Institute, and American Chemical Society, consists of five sessions: Session 1, thermal, chemical, and biological processing; Session 2 and 3, applied biological research; Session 4, bioengineering research; and Session 5, biotechnology, bioengineering, and the solution of environmental problems. It also consists of a poster session of the same five subject categories

  11. Twelfth symposium on biotechnology for fuels and chemicals: Program and abstracts

    Energy Technology Data Exchange (ETDEWEB)

    Scheitlin, F.M. (ed.)

    1990-01-01

    This report is the program and abstracts of the twelfth symposium on biotechnology for fuels and chemicals, held on May 7--11, 1990, at Gatlinburg, Tennessee. The symposium, sponsored by the Department of Energy, Oak Ridge National Laboratory, Solar Energy Research Institute, Badger Engineers, Inc., Gas Research Institute, and American Chemical Society, consists of five sessions: Session 1, thermal, chemical, and biological processing; Session 2 and 3, applied biological research; Session 4, bioengineering research; and Session 5, biotechnology, bioengineering, and the solution of environmental problems. It also consists of a poster session of the same five subject categories.

  12. Exploring Effects of Organizational Culture upon Implementation of Information Security Awareness and Training Programs within the Defense Industry Located in the Tennessee Valley Region

    Science.gov (United States)

    Grant, Robert Luther

    2017-01-01

    Data breaches due to social engineering attacks and employee negligence are on the rise. The only known defense against social engineering attacks and employee negligence is information security awareness and training. However, implementation of awareness and training programs within organizations are lagging in priority. This research used the…

  13. Program of technical assistance to the Organization for the Prohibition of Chemical Weapons - lessons learned from the U.S. program of technical assistance to IAEA safeguards. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    The Defense Nuclear Agency is sponsoring a technical study of the requirements of a vehicle to meet the OPCW`s future needs for enhanced chemical weapons verification capabilities. This report provides information about the proven mechanisms by which the U.S. provided both short- and long-term assistance to the IAEA to enhance its verification capabilities. Much of the technical assistance has generic application to international organizations verifying compliance with disarmament treaties or conventions. In addition, some of the equipment developed by the U.S. under the existing arrangements can be applied in the verification of other disarmament treaties or conventions. U.S. technical assistance to IAEA safeguards outside of the IAEA`s regular budget proved to be necessary. The U.S. technical assistance was successful in improving the effectiveness of IAEA safeguards for its most urgent responsibilities and in providing the technical elements for increased IAEA {open_quotes}readiness{close_quotes} for the postponed responsibilities deemed important for U.S. policy objectives. Much of the technical assistance was directed to generic subjects and helped to achieve a system of international verification. It is expected that the capabilities of the Organization for the Prohibition of Chemical Weapons (OPCW) to verify a state`s compliance with the {open_quotes}Chemical Weapons Convention{close_quotes} will require improvements. This report presents 18 important lessons learned from the experience of the IAEA and the U.S. Program of Technical Assistance to IAEA Safeguards (POTAS), organized into three tiers. Each lesson is presented in the report in the context of the difficulty, need and history in which the lesson was learned. Only the most important points are recapitulated in this executive summary.

  14. Nanomaterials for Defense Applications

    Science.gov (United States)

    Turaga, Uday; Singh, Vinitkumar; Lalagiri, Muralidhar; Kiekens, Paul; Ramkumar, Seshadri S.

    Nanotechnology has found a number of applications in electronics and healthcare. Within the textile field, applications of nanotechnology have been limited to filters, protective liners for chemical and biological clothing and nanocoatings. This chapter presents an overview of the applications of nanomaterials such as nanofibers and nanoparticles that are of use to military and industrial sectors. An effort has been made to categorize nanofibers based on the method of production. This chapter particularly focuses on a few latest developments that have taken place with regard to the application of nanomaterials such as metal oxides in the defense arena.

  15. Defense AT&L. Volume 40, Number 4, July-August 2011

    Science.gov (United States)

    2011-08-01

    program monitored by DCMA, KRCC, SAO-A, and ANA representatives. ANA and the new Afghanistan National Civil Order Police (ANCOP) personnel field-tested...or can’t meet a commitment, be up front about it. When you point out and explain your own lapses or potential roadblocks, it engen - ders trust in...senior military personnel, civil - ians, defense contractors, and defense industry professionals in pro- gram management and the acquisition

  16. Iran the aerial defense facing a preventive attack against the nuclear sites

    International Nuclear Information System (INIS)

    Gruselle, B.; Payre, G.

    2006-01-01

    In the context of the nuclear uranium enrichment program development facing the international opinion, the author discusses the Iran policy of implementing a defense against an aerial attack. Even with the modernization of its anti-aerial defense, the Iran will cannot support an aerial american campaign, precise and long. (A.L.B.)

  17. Computer Program for Calculation of Complex Chemical Equilibrium Compositions and Applications II. Users Manual and Program Description. 2; Users Manual and Program Description

    Science.gov (United States)

    McBride, Bonnie J.; Gordon, Sanford

    1996-01-01

    This users manual is the second part of a two-part report describing the NASA Lewis CEA (Chemical Equilibrium with Applications) program. The program obtains chemical equilibrium compositions of complex mixtures with applications to several types of problems. The topics presented in this manual are: (1) details for preparing input data sets; (2) a description of output tables for various types of problems; (3) the overall modular organization of the program with information on how to make modifications; (4) a description of the function of each subroutine; (5) error messages and their significance; and (6) a number of examples that illustrate various types of problems handled by CEA and that cover many of the options available in both input and output. Seven appendixes give information on the thermodynamic and thermal transport data used in CEA; some information on common variables used in or generated by the equilibrium module; and output tables for 14 example problems. The CEA program was written in ANSI standard FORTRAN 77. CEA should work on any system with sufficient storage. There are about 6300 lines in the source code, which uses about 225 kilobytes of memory. The compiled program takes about 975 kilobytes.

  18. Plant neighbor identity influences plant biochemistry and physiology related to defense.

    Science.gov (United States)

    Broz, Amanda K; Broeckling, Corey D; De-la-Peña, Clelia; Lewis, Matthew R; Greene, Erick; Callaway, Ragan M; Sumner, Lloyd W; Vivanco, Jorge M

    2010-06-17

    Chemical and biological processes dictate an individual organism's ability to recognize and respond to other organisms. A small but growing body of evidence suggests that plants may be capable of recognizing and responding to neighboring plants in a species specific fashion. Here we tested whether or not individuals of the invasive exotic weed, Centaurea maculosa, would modulate their defensive strategy in response to different plant neighbors. In the greenhouse, C. maculosa individuals were paired with either conspecific (C. maculosa) or heterospecific (Festuca idahoensis) plant neighbors and elicited with the plant defense signaling molecule methyl jasmonate to mimic insect herbivory. We found that elicited C. maculosa plants grown with conspecific neighbors exhibited increased levels of total phenolics, whereas those grown with heterospecific neighbors allocated more resources towards growth. To further investigate these results in the field, we conducted a metabolomics analysis to explore chemical differences between individuals of C. maculosa growing in naturally occurring conspecific and heterospecific field stands. Similar to the greenhouse results, C. maculosa individuals accumulated higher levels of defense-related secondary metabolites and lower levels of primary metabolites when growing in conspecific versus heterospecific field stands. Leaf herbivory was similar in both stand types; however, a separate field study positively correlated specialist herbivore load with higher densities of C. maculosa conspecifics. Our results suggest that an individual C. maculosa plant can change its defensive strategy based on the identity of its plant neighbors. This is likely to have important consequences for individual and community success.

  19. The Role of the Army Reserve in the Weapons of Mass Destruction/Homeland Defense Program

    National Research Council Canada - National Science Library

    Smith, Joseph

    2000-01-01

    ... attack. Given these increasing threats to the territory, population, and infrastructure of the United States, the Army Reserve should have an expanded role in providing homeland defense capabilities. The Army Reserve is well suited to homeland defense missions.

  20. Defensive effects of extrafloral nectaries in quaking aspen differ with scale.

    Science.gov (United States)

    Mortensen, Brent; Wagner, Diane; Doak, Patricia

    2011-04-01

    The effects of plant defenses on herbivory can differ among spatial scales. This may be particularly common with indirect defenses, such as extrafloral nectaries (EFNs), that attract predatory arthropods and are dependent on predator distribution, abundance, and behavior. We tested the defensive effects of EFNs in quaking aspen (Populus tremuloides Michx.) against damage by a specialist herbivore, the aspen leaf miner (Phyllocnistis populiella Cham.), at the scale of individual leaves and entire ramets (i.e., stems). Experiments excluding crawling arthropods revealed that the effects of aspen EFNs differed at the leaf and ramet scales. Crawling predators caused similar reductions in the percent leaf area mined on individual leaves with and without EFNs. However, the extent to which crawling predators increased leaf miner mortality and, consequently, reduced mining damage increased with EFN expression at the ramet scale. Thus, aspen EFNs provided a diffuse defense, reducing damage to leaves across a ramet regardless of leaf-scale EFN expression. We detected lower leaf miner damage and survival unassociated with crawling predators on EFN-bearing leaves, suggesting that direct defenses (e.g., chemical defenses) were stronger on leaves with than without EFNs. Greater direct defenses on EFN-bearing leaves may reduce the probability of losing these leaves and thus weakening ramet-scale EFN defense. Aspen growth was not related to EFN expression or the presence of crawling predators over the course of a single season. Different effects of aspen EFNs at the leaf and ramet scales suggest that future studies may benefit from examining indirect defenses simultaneously at multiple scales.

  1. 77 FR 20598 - Defense Federal Acquisition Regulation Supplement: Solicitation Provisions and Contract Clauses...

    Science.gov (United States)

    2012-04-05

    ... commercial items, that includes the clause at 252.225-7001, Buy American Act and Balance of Payments Program... Acquisitions of Commercial Items AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD... acquisition of commercial items and to specify flowdown of clauses to commercial subcontracts. DATES: Comments...

  2. Computer program determines chemical composition of physical system at equilibrium

    Science.gov (United States)

    Kwong, S. S.

    1966-01-01

    FORTRAN 4 digital computer program calculates equilibrium composition of complex, multiphase chemical systems. This is a free energy minimization method with solution of the problem reduced to mathematical operations, without concern for the chemistry involved. Also certain thermodynamic properties are determined as byproducts of the main calculations.

  3. 76 FR 27274 - Defense Federal Acquisition Regulation Supplement; Technical Amendment

    Science.gov (United States)

    2011-05-11

    ... procurement programs, it must provide written notice of the determination to the GSA Suspension and Debarment Official. List of Subjects in 48 CFR Part 209 Government procurement. Ynette R. Shelkin, Editor, Defense... suspended from procurement programs, it must provide written notice of the determination to the General...

  4. Profile of the chemicals industry in California: Californiaindustries of the future program

    Energy Technology Data Exchange (ETDEWEB)

    Galitsky, Christina; Worrell, Ernst

    2004-06-01

    The U.S. Department of Energy (DOE) Office of Industrial Technologies (OIT) established the Industries of the Future (IOF) program to increase energy efficiency, reduce waste production and to improve competitiveness, currently focusing on nine sectors. The IOF is a partnership strategy involving industry, the research community and the government, working together to identify technology needs, promote industrial partnerships and implement joint measures with all partners involved. The State Industries of the Future (SIOF) program delivers the accomplishments of the national Industries of the Future strategy to the local level, to expand the technology opportunities to a larger number of partners and reach smaller businesses and manufacturers that were not initially involved in the IOF effort. The state programs bring together industry, academia, and state agencies to address the important issues confronting industry in the state. These public-private coalitions facilitate industry solutions locally and enhance economic development. California has started a State Industries of the Future effort, in collaboration with the U.S. Department of Energy. The California Energy Commission (CEC) is leading the SIOF program in California, as part of many other programs to improve the energy efficiency and performance of industries in California. The California State IOF program aims to build a network of participants from industry, academia and government in four selected industrial sectors as a basis for the development of a strategic partnership for industrial energy efficient technology in the state. In California the IOF effort focuses petroleum refining, chemical processing, food processing and electronics. As part of this effort, the SIOF program will develop roadmaps for technology development for the selected sectors. On the basis of the roadmap, the program will develop successful projects with co-funding from state and federal government, and promote industry

  5. Chemical defence and toxins of plants

    OpenAIRE

    Yamane, H.; Konno, K.; Sabelis, M.; Takabayashi, J.; Sassa, T.; Oikawa, H.; Mander, L.; Lui, H.W.

    2010-01-01

    Higher plants protect themselves by producing a variety of secondary metabolites and proteins that are involved in defense against herbivores as well as microbial pathogens. Concerning microbial pathogenesis in plants, in many cases, it is known that phytotoxins that are produced by plant pathogens play an important role in disease development causing chlorosis, necrosis, or wilting. This chapter mainly focuses on the chemical structures, distribution, and biosynthesis of defense-related natu...

  6. Insect herbivores drive the loss of unique chemical defense in willows

    Czech Academy of Sciences Publication Activity Database

    Volf, Martin; Julkunen-Titto, R.; Hrček, Jan; Novotný, Vojtěch

    2015-01-01

    Roč. 156, č. 1 (2015), s. 88-98 ISSN 0013-8703 R&D Projects: GA ČR(CZ) GA14-04258S Grant - others:GA JU(CZ) 153/2013/P; European Social Fund(CZ) CZ.1.07/2.3.00/20.0064 Institutional support: RVO:60077344 Keywords : coevolution * defensive traits * herbivory Subject RIV: EH - Ecology, Behaviour Impact factor: 1.442, year: 2015 http://onlinelibrary.wiley.com/doi/10.1111/eea.12312/epdf

  7. RICE: a computer program for multicomponent chemically reactive flows at all speeds

    International Nuclear Information System (INIS)

    Rivard, W.C.; Farmer, O.A.; Butler, T.D.

    1974-11-01

    The fluid dynamics of chemically reactive mixtures are calculated at arbitrary flow speeds with the RICE program. The dynamics are governed by the two-dimensional, time-dependent Navier-Stokes equations together with the species transport equations and the mass-action rate equations for the chemical reactions. The mass and momentum equations for the mixture are solved implicitly by the ICE technique. The equations for total energy and species transport are solved explicitly while the chemical rate equations are solved implicitly with a time step that may be a submultiple of the hydrodynamic time step. Application is made to continuous wave HF chemical lasers to compute the supersonic mixing and chemical reactions that take place in the lasing cavity. (U.S.)

  8. Siberian Chemical Combine laboratory project work plan, fiscal year 1999

    International Nuclear Information System (INIS)

    Morgado, R.E.; Acobyan, R.; Shropsire, R.

    1998-01-01

    The Siberian Chemical Combine (SKhK), Laboratory Project Work Plan (Plan) is intended to assist the US Laboratory Project Team, and Department of Energy (DOE) staff with the management of the FY99 joint material protection control and accounting program (MPC and A) for enhancing nuclear material safeguards within the Siberian Chemical Combine. The DOE/Russian/Newly Independent States, Nuclear Material Task Force, uses a project work plan document for higher-level program management. The SKhK Plan is a component of the Russian Defense related Sites' input to that document. In addition, it contains task descriptions and a Gantt Chart covering the FY99 time-period. This FY99 window is part of a comprehensive, Project Status Gantt Chart for tasking and goal setting that extends to the year 2003. Secondary and tertiary levels of detail are incorporated therein and are for the use of laboratory project management. The SKhK Plan is a working document, and additions and modifications will be incorporated as the MPC and A project for SKhK evolves

  9. 77 FR 75414 - Establishment of Department of Defense Federal Advisory Committees

    Science.gov (United States)

    2012-12-20

    ... applicable military centers; c. Assessing the DoD approach to planning and programming facility improvements...; and facility programming responsibilities between the Assistant Secretary of Defense for Health...(P&R)) and in coordination with the appropriate Military Departments and installation commanders. The...

  10. Material Accounting and Management Control Weaknesses in the Defense Agencies' FYs 1995 and 1996 Financial Information

    National Research Council Canada - National Science Library

    Gimble, Thomas

    1997-01-01

    The primary audit objective was to summarize Defense agency accounting system weaknesses and related management control program weaknesses identified during audits of defense agencies' FYs 1995 and 1996 financial data...

  11. Defense Coastal/Estuarine Research Program (DCERP) Baseline Monitoring Plan

    Science.gov (United States)

    2007-09-19

    climatological stress (e.g., temperature, drought) and shorter-term air pollutant stress (oxidants and metals ). Heavy metals of fine PM have been...speciation of the fine and coarse PM fractions will allow distinction between different PM sources such as wind blown soil dust, including dust...emitting 12% of the total PM2.5 mass (U.S. EPA, 2004b). Source apportionment modeling of PM2.5 mass concentrations from 24 Speciation Defense Coastal

  12. Evaluation of the defensive behavior of two honeybee ecotypes using a laboratory test

    Directory of Open Access Journals (Sweden)

    Cecilia Andere

    2002-01-01

    Full Text Available Honeybee defensive behavior is a useful selection criterion, especially in areas with Africanized honeybees (Apis mellifera L. In all genetic improvement programs the selected characters must be measured with precision, and because of this we evaluated a metabolic method for testing honeybee defensive behavior in the laboratory for its usefulness in distinguishing between honeybee ecotypes and selecting honeybees based on their level of defensive responses. Ten honeybee colonies were used, five having been produced by feral queens from a subtropical region supposedly colonized by Africanized honeybees and five by queens from a temperate region apparently colonized by European honeybees. We evaluate honeybee defensive behavior using a metabolic test based on oxygen consumption after stimulation with an alarm pheromone, measuring the time to the first response, time to maximum oxygen consumption, duration of activity, oxygen consumption at first response, maximum oxygen consumption and total oxygen consumption, colonies being ranked according to the values obtained for each variable. Significant (p < 0.05 differences were detected between ecotypes for each variable but for all variables the highest rankings were obtained for colonies of subtropical origin, which had faster and more intense responses. All variables were highly associated (p < 0.05. Total oxygen consumption was the best indicator of metabolic activity for defensive behavior because it combined oxygen consumption and the length of the response. This laboratory method may be useful for evaluating the defensive behavior of honey bees in genetic programs designed to select less defensive bees.

  13. Background Material on Structural Reform of the Department of Defense

    Science.gov (United States)

    1986-03-01

    R D Y , Oklahoma THOMAS M FUGLIETTA, Pennsylvania ROY LYSON , Maryland DENNIS M HERTEL, Michigan MARILYN LLOYD. Tennessee NORMAN SISISKY, V i r...of the several Serv- ices, of defense strategy, of the overall defense program, and of how business gets transacted in the Pentagon. They must de... managing the careers of those officers best qualified for joint duty. Ac- tions are already being addressed by the Joint Chiefs to properly manage

  14. Large scale patterns of antimicrofouling defenses in the hard coral Pocillopora verrucosa in an environmental gradient along the Saudi Arabian coast of the Red Sea.

    Science.gov (United States)

    Wahl, Martin; Al Sofyani, Abdulmohsin; Saha, Mahasweta; Kruse, Inken; Lenz, Mark; Sawall, Yvonne

    2014-01-01

    Large scale patterns of ecologically relevant traits may help identify drivers of their variability and conditions beneficial or adverse to the expression of these traits. Antimicrofouling defenses in scleractinian corals regulate the establishment of the associated biofilm as well as the risks of infection. The Saudi Arabian Red Sea coast features a pronounced thermal and nutritional gradient including regions and seasons with potentially stressful conditions to corals. Assessing the patterns of antimicrofouling defenses across the Red Sea may hint at the susceptibility of corals to global change. We investigated microfouling pressure as well as the relative strength of 2 alternative antimicrofouling defenses (chemical antisettlement activity, mucus release) along the pronounced environmental gradient along the Saudi Arabian Red Sea coast in 2 successive years. Microfouling pressure was exceptionally low along most of the coast but sharply increased at the southernmost sites. Mucus release correlated with temperature. Chemical defense tended to anti-correlate with mucus release. As a result, the combined action of mucus release and chemical antimicrofouling defense seemed to warrant sufficient defense against microbes along the entire coast. In the future, however, we expect enhanced energetic strain on corals when warming and/or eutrophication lead to higher bacterial fouling pressure and a shift towards putatively more costly defense by mucus release.

  15. Developing an institutional strategy for transporting defense transuranic waste materials

    International Nuclear Information System (INIS)

    Guerrero, J.V.; Kresny, H.S.

    1986-01-01

    In late 1988, the US Department of Energy (DOE) expects to begin emplacing transuranic waste materials in the Waste Isolation Pilot Plant (WIPP), an R and D facility to demonstrate the safe disposal of radioactive wastes resulting from defense program activities. Transuranic wastes are production-related materials, e.g., clothes, rags, tools, and similar items. These materials are contaminated with alpha-emitting transuranium radionuclides with half-lives of > 20 yr and concentrations > 100 nCi/g. Much of the institutional groundwork has been done with local communities and the State of New Mexico on the siting and construction of the facility. A key to the success of the emplacement demonstration, however, will be a qualified transportation system together with institutional acceptance of the proposed shipments. The DOE's Defense Transuranic Waste Program, and its contractors, has lead responsibility for achieving this goal. The Joint Integration Office (JIO) of the DOE, located in Albuquerque, New Mexico, is taking the lead in implementing an integrated strategy for assessing nationwide institutional concerns over transportation of defense transuranic wastes and in developing ways to resolve or mitigate these concerns. Parallel prototype programs are under way to introduce both the new packaging systems and the institutional strategy to interested publics and organizations

  16. Dynamic defense workshop :

    Energy Technology Data Exchange (ETDEWEB)

    Crosby, Sean Michael; Doak, Justin E.; Haas, Jason Juedes.; Helinski, Ryan; Lamb, Christopher C.

    2013-02-01

    On September 5th and 6th, 2012, the Dynamic Defense Workshop: From Research to Practice brought together researchers from academia, industry, and Sandia with the goals of increasing collaboration between Sandia National Laboratories and external organizations, de ning and un- derstanding dynamic, or moving target, defense concepts and directions, and gaining a greater understanding of the state of the art for dynamic defense. Through the workshop, we broadened and re ned our de nition and understanding, identi ed new approaches to inherent challenges, and de ned principles of dynamic defense. Half of the workshop was devoted to presentations of current state-of-the-art work. Presentation topics included areas such as the failure of current defenses, threats, techniques, goals of dynamic defense, theory, foundations of dynamic defense, future directions and open research questions related to dynamic defense. The remainder of the workshop was discussion, which was broken down into sessions on de ning challenges, applications to host or mobile environments, applications to enterprise network environments, exploring research and operational taxonomies, and determining how to apply scienti c rigor to and investigating the eld of dynamic defense.

  17. Cooperative Threat Reduction: Status of Defense Conversion Efforts in the Former Soviet Union

    National Research Council Canada - National Science Library

    1997-01-01

    DOD's program to convert former Soviet Union defense industries to commercial enterprises is part of the Cooperative Threat Reduction program, which DOD has supported since 1992 to reduce the weapons...

  18. 32 CFR 634.10 - Remedial driver training programs.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Remedial driver training programs. 634.10 Section 634.10 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Driving Privileges § 634.10 Remedial driver training programs. (a) Navy...

  19. Technical Soddi Defenses: The Trojan Horse Defense Revisited

    Directory of Open Access Journals (Sweden)

    Chad Steel

    2014-12-01

    Full Text Available In 2004, the Trojan horse defense was at a crossroads, with two child pornography cases where it was successfully employed in the United Kingdom, resulting in acquittals.  The original Trojan horse defense has now become part of the more general “technical SODDI” defense, which includes the possibility of unknown actors using unsecured Wi-Fi connections or having physical access to a computer to perform criminal acts.  In the past ten years, it has failed to be effective in the United States for criminal cases, with no published acquittals in cases where it was the primary defense.  In the criminal cases where it has been used as leverage in plea negotiations, there has been either poor forensics performed by the prosecution or political pressure to resolve a matter.  On the civil side, however, the defense has been wildly successful, effectively shutting down large John Doe copyright infringement litigation against non-commercial violators.  

  20. The chemistry of antipredator defense by secondary compounds in neotropical lepidoptera: facts, perspectives and caveats

    Directory of Open Access Journals (Sweden)

    Trigo José R.

    2000-01-01

    Full Text Available Chemical defense against predation in butterflies and moths has been studied since nineteenth century. A classical example is that of the larvae of the monarch butterfly Danaus plexippus, which feed on leaves of Asclepias curassavica (Asclepiadaceae, sequestering cardenolides. The adults are protected against predation by birds. Several other substances may be involved in chemical defense, such as iridoid glycosides, cyanogenic glycosides, glucosinolates, pyrrolizidine and tropane alkaloids, aristolochic acids, glycosidase inhibitors and pyrazines. The acquisition of these substances by lepidopterans can be due to sequestration from larval or adult host plants or de novo biosynthesis. Many Lepidoptera are known to be unpalatable, including the butterflies Troidini (Papilionidae, Pierinae (Pieridae, Eurytelinae, Melitaeinae, Danainae, Ithomiinae, Heliconiinae and Acraeinae (Nymphalidae, and Arctiidae moths, but knowledge of the chemical substances responsible for property is often scarce. This review discusses mainly three topics: field and laboratory observations on rejection of butterflies and moths by predators, correlation between unpalatability and chemicals found in these insects, and bioassays that test the activity of these chemicals against predators. Perspectives and future directions are suggested for this subject.

  1. Future Years Defense Program (FYDP) Structure

    Science.gov (United States)

    2004-04-01

    computer miniframe . Intelligence Telecommunications Page E-330 of 1748DoD 7045.7-H, March, 2004 03 Command, Control, Comm, Intel, & SpaceProgram...communications programs, i.e., STARCOM, NAVCOM, and AIRCOM. Costs of equipment - computer miniframes , peripheral devices, communications processors...the general service communications programs, i.e., STARCOM, NAVCOM, and AIRCOM. Costs of equipment - computer miniframes , peripheral devices

  2. Disposal of defense spent fuel and HLW from the Idaho Chemical Processing Plant

    International Nuclear Information System (INIS)

    Ermold, L.F.; Loo, H.H.; Klingler, R.D.; Herzog, J.D.; Knecht, D.A.

    1992-12-01

    Acid high-level radioactive waste (HLW) resulting from fuel reprocessing at the Idaho Chemical Processing Plant (ICPP) for the US Department of Energy (DOE) has been solidified to a calcine since 1963 and stored in stainless steel bins enclosed by concrete vaults. Several different types of unprocessed irradiated DOE-owned fuels are also in storage ate the ICPP. In April, 1992, DOE announced that spent fuel would no longer be reprocessed to recover enriched uranium and called for a shutdown of the reprocessing facilities at the ICPP. A new Spent Fuel and HLW Technology Development program was subsequently initiated to develop technologies for immobilizing ICPP spent fuels and HLW for disposal, in accordance with the Nuclear Waste Policy Act. The Program elements include Systems Analysis, Graphite Fuel Disposal, Other Spent Fuel Disposal, Sodium-Bearing Liquid Waste Processing, Calcine Immobilization, and Metal Recycle/Waste Minimization. This paper presents an overview of the ICPP radioactive wastes and current spent fuels, with an emphasis on the description of HLW and spent fuels requiring repository disposal

  3. Civil Defense, U. S. A.: A Programmed Orientation to Civil Defense. Unit 2. Nuclear Weapons Effects and Shelter.

    Science.gov (United States)

    Defense Civil Preparedness Agency (DOD), Battle Creek, MI.

    Basic information about nuclear weapons is presented so that their effects can be meaningfully related to the defensive countermeasures which will be most effective against them. Major topics include: (1) Explosive power of nuclear weapons, (2) Major effects of nuclear explosions, (3) Two basic types of nuclear explosions, (4) Contrast between air…

  4. Information resources for assessing health effects from chemical exposure: Office of pesticides programs

    Energy Technology Data Exchange (ETDEWEB)

    Fenner-Crisp, P. [Environmental Protection Agency, Washington, DC (United States)

    1990-12-31

    The US Environmental Protection Agency (EPA) Office of Pesticide Programs is trying to develop a complete picture of a chemical`s toxicity and exposure profile. It is also important to share information in the office`s files because of pesticides, particularly as a consequence of agricultural use, find their way into places not necessarily intended.

  5. Program Implementation Plan

    International Nuclear Information System (INIS)

    1987-06-01

    The Program Implementation Plan (PIP) describes the US Department of Energy's (DOE's) current approaches for managing the permanent disposal of defense high-level waste (HLW), transuranic (TRU) waste, and low-level waste (LLW) from atomic energy defense activities. It documents the implementation of the HLW and TRU waste policies as stated in the Defense Waste Management Plan (DWMP) (DOE/DP-0015), dated June 1983, and also addresses the management of LLW. The narrative reflects both accomplishments and changes in the scope of activities. All cost tables and milestone schedules are current as of January 1987. The goals of the program, to provide safe processing and utilization, storage, and disposal of DOE radioactive waste and byproducts to support defense nuclear materials production activities, and to implement cost-effective improvements in all of its ongoing and planned activities, have not changed

  6. From nuclides to nerve gas: The development of the Chemical Stockpile Emergency Preparedness Exercise Program

    International Nuclear Information System (INIS)

    Gant, K.S.; Adler, M.V.

    1991-01-01

    The Army and the Federal Emergency Management Agency established the Chemical Stockpile Emergency Preparedness Program (CSEPP), to improve emergency preparedness around each location storing the nation's aging stockpile of unitary chemical weapons. The CSEPP requires that a series of exercises be conducted at each location on a regular schedule. The CSEPP exercise program drew upon the existing Army and civilian exercises. Merging the exercise traditions of both the communities and installations into a joint exercise program acceptable to both sides and the particular nature of the hazard required a number of adjustments in the usual approaches. 14 refs., 1 fig

  7. Early Birds in Korea: Exporting Defense AT and L Has Far Reaching Impact

    Science.gov (United States)

    2015-11-01

    51 Defense AT&L: November–December 2015 Early Birds in Korea ”Exporting” Defense AT&L Has Far-Reaching Impact DT Tripp n Hwa Yu Tripp is...Defense Acquisition Program Administration. “The early bird catches the worm.” Who doesn’t know this proverb? A study club in the Republic of Korea (ROK...name originated from that tenet as the “Early Birds Study”—or the EBS, for short. This year, the EBS will celebrate the 10th anniversary of its

  8. [Study of defense styles, defenses and coping strategies in alcohol-dependent population].

    Science.gov (United States)

    Ribadier, A; Varescon, I

    2017-05-01

    Defense mechanisms have been seen to greatly change over time and across different definitions made by different theoretical currents. Recently with the definition provided by the DSM IV, defense mechanisms have integrated the concept of coping as a defensive factor. These mechanisms are no longer considered just through a psychodynamic approach but also through a cognitive and behavioral one. In recent years, new theories have therefore integrated these two components of the defensive operation. According to Chabrol and Callahan (2013), defense mechanisms precede coping strategies. In individuals with psychopathological disorders, these authors indicate a relative stability of these mechanisms. Also, we asked about the presence of unique characteristics among people with alcohol dependence. Indeed, studies conducted with people with alcohol dependence highlight the presence of a neurotic defense style and some highly immature defenses (projection, acting out, splitting and somatization). In terms of coping strategies, persons with alcohol dependence preferentially use avoidant strategies and strategies focused on emotion. However, although several studies have been conducted to assess coping strategies and defense styles within a population of individuals with an alcohol problem, at the present time none of them has taken into account all these aspects of defense mechanisms. The aim of this study is therefore to study the defenses and defense styles and coping strategies in an alcohol-dependent population. This multicenter study (3 CHU, 1 center of supportive care and prevention in addiction and 1 clinic) received a favorable opinion of an Institutional Review Board (IRB Registration #: 00001072). Eighty alcohol-dependent individuals responded to a questionnaire assessing sociodemographic characteristics and elements related to the course of consumption. Coping strategies were assessed by means of a questionnaire validated in French: the Brief Cope. The Defense

  9. Plant neighbor identity influences plant biochemistry and physiology related to defense

    Directory of Open Access Journals (Sweden)

    Callaway Ragan M

    2010-06-01

    Full Text Available Abstract Background Chemical and biological processes dictate an individual organism's ability to recognize and respond to other organisms. A small but growing body of evidence suggests that plants may be capable of recognizing and responding to neighboring plants in a species specific fashion. Here we tested whether or not individuals of the invasive exotic weed, Centaurea maculosa, would modulate their defensive strategy in response to different plant neighbors. Results In the greenhouse, C. maculosa individuals were paired with either conspecific (C. maculosa or heterospecific (Festuca idahoensis plant neighbors and elicited with the plant defense signaling molecule methyl jasmonate to mimic insect herbivory. We found that elicited C. maculosa plants grown with conspecific neighbors exhibited increased levels of total phenolics, whereas those grown with heterospecific neighbors allocated more resources towards growth. To further investigate these results in the field, we conducted a metabolomics analysis to explore chemical differences between individuals of C. maculosa growing in naturally occurring conspecific and heterospecific field stands. Similar to the greenhouse results, C. maculosa individuals accumulated higher levels of defense-related secondary metabolites and lower levels of primary metabolites when growing in conspecific versus heterospecific field stands. Leaf herbivory was similar in both stand types; however, a separate field study positively correlated specialist herbivore load with higher densities of C. maculosa conspecifics. Conclusions Our results suggest that an individual C. maculosa plant can change its defensive strategy based on the identity of its plant neighbors. This is likely to have important consequences for individual and community success.

  10. Defense Waste Processing Facility Simulant Chemical Processing Cell Studies for Sludge Batch 9

    International Nuclear Information System (INIS)

    Smith, Tara E.; Newell, J. David; Woodham, Wesley H.

    2016-01-01

    The Savannah River National Laboratory (SRNL) received a technical task request from Defense Waste Processing Facility (DWPF) and Saltstone Engineering to perform simulant tests to support the qualification of Sludge Batch 9 (SB9) and to develop the flowsheet for SB9 in the DWPF. These efforts pertained to the DWPF Chemical Process Cell (CPC). CPC experiments were performed using SB9 simulant (SB9A) to qualify SB9 for sludge-only and coupled processing using the nitric-formic flowsheet in the DWPF. Two simulant batches were prepared, one representing SB8 Tank 40H and another representing SB9 Tank 51H. The simulant used for SB9 qualification testing was prepared by blending the SB8 Tank 40H and SB9 Tank 51H simulants. The blended simulant is referred to as SB9A. Eleven CPC experiments were run with an acid stoichiometry ranging between 105% and 145% of the Koopman minimum acid equation (KMA), which is equivalent to 109.7% and 151.5% of the Hsu minimum acid factor. Three runs were performed in the 1L laboratory scale setup, whereas the remainder were in the 4L laboratory scale setup. Sludge Receipt and Adjustment Tank (SRAT) and Slurry Mix Evaporator (SME) cycles were performed on nine of the eleven. The other two were SRAT cycles only. One coupled flowsheet and one extended run were performed for SRAT and SME processing. Samples of the condensate, sludge, and off-gas were taken to monitor the chemistry of the CPC experiments.

  11. Chemical defenses and resource trade-offs structure sponge communities on Caribbean coral reefs.

    Science.gov (United States)

    Loh, Tse-Lynn; Pawlik, Joseph R

    2014-03-18

    Ecological studies have rarely been performed at the community level across a large biogeographic region. Sponges are now the primary habitat-forming organisms on Caribbean coral reefs. Recent species-level investigations have demonstrated that predatory fishes (angelfishes and some parrotfishes) differentially graze sponges that lack chemical defenses, while co-occurring, palatable species heal, grow, reproduce, or recruit at faster rates than defended species. Our prediction, based on resource allocation theory, was that predator removal would result in a greater proportion of palatable species in the sponge community on overfished reefs. We tested this prediction by performing surveys of sponge and fish community composition on reefs having different levels of fishing intensity across the Caribbean. A total of 109 sponge species was recorded from 69 sites, with the 10 most common species comprising 51.0% of sponge cover (3.6-7.7% per species). Nonmetric multidimensional scaling indicated that the species composition of sponge communities depended more on the abundance of sponge-eating fishes than geographic location. Across all sites, multiple-regression analyses revealed that spongivore abundance explained 32.8% of the variation in the proportion of palatable sponges, but when data were limited to geographically adjacent locations with strongly contrasting levels of fishing pressure (Cayman Islands and Jamaica; Curaçao, Bonaire, and Martinique), the adjusted R(2) values were much higher (76.5% and 94.6%, respectively). Overfishing of Caribbean coral reefs, particularly by fish trapping, removes sponge predators and is likely to result in greater competition for space between faster-growing palatable sponges and endangered reef-building corals.

  12. Chemical defense in Elodea nuttallii reduces feeding and growth of aquatic herbivorous Lepidoptera.

    Science.gov (United States)

    Erhard, Daniela; Pohnert, Georg; Gross, Elisabeth M

    2007-08-01

    The submersed macrophyte Elodea nuttallii (Hydrocharitaceae) is invasive in Europe and frequently found in aquatic plant communities. Many invertebrate herbivores, such as larvae of the generalist aquatic moth, Acentria ephemerella (Lepidoptera, Pyralidae), avoid feeding on E. nuttallii and preferably consume native species. First instar larvae exhibited a high mortality on E. nuttallii compared to the native macrophyte Potamogeton perfoliatus. Mortality of older larvae was also high when fed E. nuttallii exposed to high light intensities. Growth of older larvae was strongly reduced on E. nuttallii compared to pondweeds (Potamogeton lucens). Neither differences in nitrogen nor phosphorus content explained the different performance on these submerged macrophytes, but plants differed in their flavonoid content. To investigate whether plant-derived allelochemicals from E. nuttallii affect larval performance in the same way as live plants, we developed a functional bioassay, in which Acentria larvae were reared on artificial diets. We offered larvae Potamogeton leaf disks coated with crude Elodea extracts and partially purified flavonoids. Elodea extracts deterred larvae from feeding on otherwise preferred Potamogeton leaves, and yet, unknown compounds in the extracts reduced growth and survival of Acentria. The flavonoid fraction containing luteolin-7-O-diglucuronide, apigenin-7-O-diglucuronide, and chrysoeriol-7-O-diglucuronide strongly reduced feeding of larvae, but did not increase mortality. The concentrations of these compounds in our assays were 0.01-0.09% of plant dry mass, which is in the lower range of concentrations found in the field (0.02-1.2%). Chemical defense in E. nuttallii thus plays an ecologically relevant role in this aquatic plant-herbivore system.

  13. Defense Waste Processing Facility Simulant Chemical Processing Cell Studies for Sludge Batch 9

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Tara E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Newell, J. David [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Woodham, Wesley H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-08-10

    The Savannah River National Laboratory (SRNL) received a technical task request from Defense Waste Processing Facility (DWPF) and Saltstone Engineering to perform simulant tests to support the qualification of Sludge Batch 9 (SB9) and to develop the flowsheet for SB9 in the DWPF. These efforts pertained to the DWPF Chemical Process Cell (CPC). CPC experiments were performed using SB9 simulant (SB9A) to qualify SB9 for sludge-only and coupled processing using the nitric-formic flowsheet in the DWPF. Two simulant batches were prepared, one representing SB8 Tank 40H and another representing SB9 Tank 51H. The simulant used for SB9 qualification testing was prepared by blending the SB8 Tank 40H and SB9 Tank 51H simulants. The blended simulant is referred to as SB9A. Eleven CPC experiments were run with an acid stoichiometry ranging between 105% and 145% of the Koopman minimum acid equation (KMA), which is equivalent to 109.7% and 151.5% of the Hsu minimum acid factor. Three runs were performed in the 1L laboratory scale setup, whereas the remainder were in the 4L laboratory scale setup. Sludge Receipt and Adjustment Tank (SRAT) and Slurry Mix Evaporator (SME) cycles were performed on nine of the eleven. The other two were SRAT cycles only. One coupled flowsheet and one extended run were performed for SRAT and SME processing. Samples of the condensate, sludge, and off-gas were taken to monitor the chemistry of the CPC experiments.

  14. Ballistic missile defense effectiveness

    Science.gov (United States)

    Lewis, George N.

    2017-11-01

    The potential effectiveness of ballistic missile defenses today remains a subject of debate. After a brief discussion of terminal and boost phase defenses, this chapter will focus on long-range midcourse defenses. The problems posed by potential countermeasures to such midcourse defenses are discussed as are the sensor capabilities a defense might have available to attempt to discriminate the actual missile warhead in a countermeasures environment. The role of flight testing in assessing ballistic missile defense effectiveness is discussed. Arguments made about effectiveness by missile defense supporters and critics are summarized.

  15. Copper Contamination Impairs Herbivore Initiation of Seaweed Inducible Defenses and Decreases Their Effectiveness.

    Directory of Open Access Journals (Sweden)

    Alexandria M Warneke

    Full Text Available Seaweed-herbivore interactions are often mediated by environmental conditions, yet the roles of emerging anthropogenic stressors on these interactions are poorly understood. For example, chemical contaminants have unknown consequences on seaweed inducible resistance and herbivore response to these defenses despite known deleterious effects of contaminants on animal inducible defenses. Here, we investigated the effect of copper contamination on the interactions between a snail herbivore and a brown seaweed that displays inducible resistance to grazing. We examined seaweed inducible resistance and its effectiveness for organisms exposed to copper at two time points, either during induction or after herbivores had already induced seaweed defenses. Under ambient conditions, non-grazed tissues were more palatable than grazed tissues. However, copper additions negated the preference for non-grazed tissues regardless of the timing of copper exposure, suggesting that copper decreased both how herbivores initiated these inducible defenses and their subsequent effectiveness. Copper decreased stimulation of defenses, at least in part, by suppressing snail grazing pressure-the cue that turns inducible defenses on. Copper decreased effectiveness of defenses by preventing snails from preferentially consuming non-grazed seaweed. Thus, contaminants can potentially stress communities by changing seaweed-herbivore interactions mediated via inducible defenses. Given the ubiquity of seaweed inducible resistance and their potential influence on herbivores, we hypothesize that copper contamination may change the impact of these resistant traits on herbivores.

  16. 76 FR 72391 - Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense...

    Science.gov (United States)

    2011-11-23

    ... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2011-OS-0055] Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense Logistics Agency Actions AGENCY: Defense Logistics Agency, Department of Defense. ACTION: Revised Defense Logistics Agency...

  17. Rosoboroneksport: Arms Sales and the Structure of Russian Defense Industry

    National Research Council Canada - National Science Library

    Blank, Stephen J

    2007-01-01

    .... Although Russian observers believe that Washington did so because of these firms arms sales to Venezuela, these sales to such dangerous states oblige us to analyze the Russian defense export program...

  18. Program Management Challenges in a Joint Service Environment

    National Research Council Canada - National Science Library

    Taneyhill, Dorothy E

    2007-01-01

    ... or modifications of the same design. The Interim Defense Acquisition Guidebook defines a Joint Program Management Office as any defense acquisition system, subsystem, component, or technology program that involves formal management...

  19. 48 CFR 225.7005 - Restriction on certain chemical weapons antidote.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Restriction on certain chemical weapons antidote. 225.7005 Section 225.7005 Federal Acquisition Regulations System DEFENSE... on certain chemical weapons antidote. ...

  20. The defense waste processing facility: the final processing step for defense high-level waste disposal

    International Nuclear Information System (INIS)

    Cowan, S.P.; Sprecher, W.M.; Walton, R.D.

    1983-01-01

    The policy of the U.S. Department of Energy is to pursue an aggressive and credible waste management program that advocates final disposal of government generated (defense) high-level nuclear wastes in a manner consistent with environmental, health, and safety responsibilities and requirements. The Defense Waste Processing Facility (DWPF) is an essential component of the Department's program. It is the first project undertaken in the United States to immobilize government generated high-level nuclear wastes for geologic disposal. The DWPF will be built at the Department's Savannah River Plant near Aiken, South Carolina. When construction is complete in 1989, the DWPF will begin processing the high-level waste at the Savannah River Plant into a borosilicate glass form, a highly insoluble and non-dispersable product, in easily handled canisters. The immobilized waste will be stored on site followed by transportation to and disposal in a Federal repository. The focus of this paper is on the DWPF. The paper discusses issues which justify the project, summarizes its technical attributes, analyzes relevant environmental and insitutional factors, describes the management approach followed in transforming technical and other concepts into concrete and steel, and concludes with observations about the future role of the facility

  1. Silverleaf whitefly induces salicylic acid defenses and suppresses effectual jasmonic acid defenses.

    Science.gov (United States)

    Zarate, Sonia I; Kempema, Louisa A; Walling, Linda L

    2007-02-01

    The basal defenses important in curtailing the development of the phloem-feeding silverleaf whitefly (Bemisia tabaci type B; SLWF) on Arabidopsis (Arabidopsis thaliana) were investigated. Sentinel defense gene RNAs were monitored in SLWF-infested and control plants. Salicylic acid (SA)-responsive gene transcripts accumulated locally (PR1, BGL2, PR5, SID2, EDS5, PAD4) and systemically (PR1, BGL2, PR5) during SLWF nymph feeding. In contrast, jasmonic acid (JA)- and ethylene-dependent RNAs (PDF1.2, VSP1, HEL, THI2.1, FAD3, ERS1, ERF1) were repressed or not modulated in SLWF-infested leaves. To test for a role of SA and JA pathways in basal defense, SLWF development on mutant and transgenic lines that constitutively activate or impair defense pathways was determined. By monitoring the percentage of SLWF nymphs in each instar, we show that mutants that activate SA defenses (cim10) or impair JA defenses (coi1) accelerated SLWF nymphal development. Reciprocally, mutants that activate JA defenses (cev1) or impair SA defenses (npr1, NahG) slowed SLWF nymphal development. Furthermore, when npr1 plants, which do not activate downstream SA defenses, were treated with methyl jasmonate, a dramatic delay in nymph development was observed. Collectively, these results showed that SLWF-repressed, JA-regulated defenses were associated with basal defense to the SLWF.

  2. Defense bill: Earmarking as usual

    Science.gov (United States)

    Earmarked funds in the $268 billion defense appropriations bill for fiscal year 1991 stirred congressional debate in late October. Senator Sam Nunn (D-Ga.), chairman of the Senate Armed Services Committee, charged that the defense bill contains questionable projects totaling tens of millions of dollars. AGU opposes legislative earmarking of money for particular institutions, maintaining that the practice prevents the best use of federal funding by circumventing competitive review. Nunn noted on the Senate floor that the appropriations bill provided specific funds for cited institutions—contravening a federal law promoting competition. “ If these programs have merit, they will succeed in a fair and competent review in competition,” Nunn said. “If no other institution in the country is able to compete, there should be no fear whatever of competition… But no one else in the world is allowed to compete to work on these projects.”

  3. Predicting the Proficiency of Arabic and Persian Linguists Trained at the Defense Language Institute Foreign Language Center

    National Research Council Canada - National Science Library

    DeRamus, Nicole

    1999-01-01

    The mission of the Defense Language Institute Foreign Language Center (DLIFLC) is to train, sustain, and evaluate foreign language skills of linguists under the guidelines of the Defense Foreign Language Program (DFLP...

  4. 32 CFR 34.41 - Monitoring and reporting program and financial performance.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Monitoring and reporting program and financial performance. 34.41 Section 34.41 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD... ORGANIZATIONS Post-award Requirements Reports and Records § 34.41 Monitoring and reporting program and financial...

  5. Methods for estimating costs of transporting spent fuel and defense high-level radioactive waste for the civilian radioactive waste management program

    International Nuclear Information System (INIS)

    Darrough, M.E.; Lilly, M.J.

    1989-01-01

    The US Department of Energy (DOE), through the Office of Civilian Radioactive Waste Management, is planning and developing a transportation program for the shipment of spent fuel and defense high-level waste from current storage locations to the site of the mined geologic repository. In addition to its responsibility for providing a safe transportation system, the DOE will assure that the transportation program will function with the other system components to create an integrated waste management system. In meeting these objectives, the DOE will use private industry to the maximum extent practicable and in a manner that is cost effective. This paper discusses various methodologies used for estimating costs for the national radioactive waste transportation system. Estimating these transportation costs is a complex effort, as the high-level radioactive waste transportation system, itself, will be complex. Spent fuel and high-level waste will be transported from more than 100 nuclear power plants and defense sites across the continental US, using multiple transport modes (truck, rail, and barge/rail) and varying sizes and types of casks. Advance notification to corridor states will be given and scheduling will need to be coordinated with utilities, carriers, state and local officials, and the DOE waste acceptance facilities. Additionally, the waste forms will vary in terms of reactor type, size, weight, age, radioactivity, and temperature

  6. Estimated Impacts of Sequestration-Level Funding: United States Department of Defense Fiscal Year 1015 Budget Request

    Science.gov (United States)

    2014-04-01

    Prepositioned Stocks, and Environmental Restoration. The other O&M portfolio indirectly supports Service readiness by funding such areas as training and...and administration. The portfolio also supports intelligence programs and defense-wide activities, such as the Defense Health Program, Special...2.0) (1.6) (1.1) (0.9) (5.7) SUMMARY OF MILCON Under BCA levels, the MILCON accounts would decline to allow for the rebalancing of resources

  7. Missile Defense: Ballistic Missile Defense System Testing Delays Affect Delivery of Capabilities

    Science.gov (United States)

    2016-04-28

    Page 1 GAO-16-339R Ballistic Missile Defense 441 G St. N.W. Washington, DC 20548 April 28, 2016 Congressional Committees Missile Defense... Ballistic Missile Defense System Testing Delays Affect Delivery of Capabilities For over half a century, the Department of Defense (DOD) has been...funding efforts to develop a system to detect, track, and defeat enemy ballistic missiles. The current system—the Ballistic Missile Defense System

  8. Broad Overview of Energy Efficiency and Renewable Energy Opportunities for Department of Defense Installations

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, E.; Antkowiak, M.; Butt, R.; Davis, J.; Dean, J.; Hillesheim, M.; Hotchkiss, E.; Hunsberger, R.; Kandt, A.; Lund, J.; Massey, K.; Robichaud, R.; Stafford, B.; Visser, C.

    2011-08-01

    The Strategic Environmental Research and Developmental Program (SERDP)/Environmental Security Technology Certification Program (ESTCP) is the Department of Defense?s (DOD) environmental science and technology program focusing on issues related to environment and energy for the military services. The SERDP/ESTCP Office requested that the National Renewable Energy Laboratory (NREL) provide technical assistance with strategic planning by evaluating the potential for several types of renewable energy technologies at DOD installations. NREL was tasked to provide technical expertise and strategic advice for the feasibility of geothermal resources, waste-to-energy technology, photovoltaics (PV), wind, microgrids, and building system technologies on military installations. This technical report is the deliverable for these tasks.

  9. Hazardous Waste Remedial Actions Program: integrating waste management

    International Nuclear Information System (INIS)

    Petty, J.L.; Sharples, F.E.

    1986-01-01

    The Hazardous Waste Remedial Actions Program was established to integrate Defense Programs' activities in hazardous and mixed waste management. The Program currently provides centralized planning and technical support to the Office of the Assistant Secretary for Defense Programs. More direct project management responsibilities may be assumed in the future. The Program, under the direction of the ASDP's Office of Defense Waste and Transportation Management, interacts with numerous organizational entities of the Department. The Oak Ridge Operations Office has been designated as the Lead Field Office. The Program's four current components cover remedial action project identification and prioritization; technology adaptation; an informative system; and a strategy study for long-term, ''corporate'' project and facility planning

  10. The Navy/NASA Engine Program (NNEP89): Interfacing the program for the calculation of complex Chemical Equilibrium Compositions (CEC)

    Science.gov (United States)

    Gordon, Sanford

    1991-01-01

    The NNEP is a general computer program for calculating aircraft engine performance. NNEP has been used extensively to calculate the design and off-design (matched) performance of a broad range of turbine engines, ranging from subsonic turboprops to variable cycle engines for supersonic transports. Recently, however, there has been increased interest in applications for which NNEP is not capable of simulating, such as the use of alternate fuels including cryogenic fuels and the inclusion of chemical dissociation effects at high temperatures. To overcome these limitations, NNEP was extended by including a general chemical equilibrium method. This permits consideration of any propellant system and the calculation of performance with dissociation effects. The new extended program is referred to as NNEP89.

  11. Ada--Programming Language of the Future.

    Science.gov (United States)

    Rudd, David

    1983-01-01

    Ada is a programing language developed for the Department of Defense, with a registered trademark. It was named for Ada Augusta, coworker of Charles Babbage and the world's first programer. The Department of Defense hopes to prevent variations and to establish Ada as a consistent, standardized language. (MNS)

  12. Environmental data quality problems: ''Technical'' vs. ''legal'' defensibility

    International Nuclear Information System (INIS)

    Luker, R.S.; Brooks, M.C.; Stagg, D.D.

    1995-01-01

    Two significant aspects of environmental data quality are currently being emphasized throughout the industry as critical precursors to environmental decision making: technical integrity and legal defensibility. Because audit findings and consequent perceptions by a client often pose more questions than answers--especially with respect to the ''systemic'' nature and significance of problems based on nonstatistical, ad hoc sampling of large programs--quality assurance in environmental restoration must do more than implement traditional administrative controls. A major problem persists in achieving a consensus opinion between quality assurance and technical staff on the significance of various data problems. This case study compares and contrasts ''technical integrity'' and ''legal defensibility'', and provides performance measures developed to optimize both components in a large, complex DOE environmental restoration program. Performance measures of both administrative and technical processes are being used to ensure that conclusions drawn concerning ''systematic'' problems are not premature, and are founded on thorough, representative aspects of the program. Improved methods to reach consensus opinions on environmental decision-making are imperative and environmental data quality, the cornerstone on which the decisions are built, must be not only scientifically solid, but perceived as solid, if stakeholders are to be satisfied

  13. Chemical warfare in termites

    Czech Academy of Sciences Publication Activity Database

    Šobotník, Jan; Jirošová, Anna; Hanus, Robert

    2010-01-01

    Roč. 56, č. 9 (2010), s. 1012-1021 ISSN 0022-1910 R&D Projects: GA AV ČR IAA600550614 Institutional research plan: CEZ:AV0Z40550506 Keywords : Isoptera * chemical defense * exocrine gland * frontal gland Subject RIV: CC - Organic Chemistry Impact factor: 2.310, year: 2010

  14. Defense Human Resources Activity > PERSEREC

    Science.gov (United States)

    Skip to main content (Press Enter). Toggle navigation Defense Human Resources Activity Search Search Defense Human Resources Activity: Search Search Defense Human Resources Activity: Search Defense Human Resources Activity U.S. Department of Defense Defense Human Resources Activity Overview

  15. Overview of the French program in chemical separations and transmutation

    International Nuclear Information System (INIS)

    Baudin, G.

    1993-01-01

    A long-range effort has begun in France that is aimed at the reduction of the volume and activity level of wastes containing long half-life radionuclides. This effort constitutes the SPIN (SeParations-INcineration) Program which investigates separations techniques that can improve current reprocessing technologies coupled with destruction of long-lived species through transmutation. Removal and destruction of specific radionuclides (e.g., neptunium, americium, technetium, iodine, cesium, and strontium) will be emphasized. Advanced solvent extraction chemistry focusing, for example, on development and implementation of diamides for actinide-lanthanide separations constitutes an important component of the SPIN program. The second component of the program focuses on inventory reductions through transmutation of such long-lived nuclides in fast reactor systems (Super Phenix). Accelerator-based systems are also being evaluated as a possible long-term option. Both of these components of the SPIN program are aimed at further reduction of the potential radiotoxicity and radiological impact of high-level wastes destined for geological storage. In this presentation, major activities of the SPIN Program will be described with emphasis on activities related to advanced chemical separations

  16. Defense islands in bacterial and archaeal genomes and prediction of novel defense systems.

    Science.gov (United States)

    Makarova, Kira S; Wolf, Yuri I; Snir, Sagi; Koonin, Eugene V

    2011-11-01

    The arms race between cellular life forms and viruses is a major driving force of evolution. A substantial fraction of bacterial and archaeal genomes is dedicated to antivirus defense. We analyzed the distribution of defense genes and typical mobilome components (such as viral and transposon genes) in bacterial and archaeal genomes and demonstrated statistically significant clustering of antivirus defense systems and mobile genes and elements in genomic islands. The defense islands are enriched in putative operons and contain numerous overrepresented gene families. A detailed sequence analysis of the proteins encoded by genes in these families shows that many of them are diverged variants of known defense system components, whereas others show features, such as characteristic operonic organization, that are suggestive of novel defense systems. Thus, genomic islands provide abundant material for the experimental study of bacterial and archaeal antivirus defense. Except for the CRISPR-Cas systems, different classes of defense systems, in particular toxin-antitoxin and restriction-modification systems, show nonrandom clustering in defense islands. It remains unclear to what extent these associations reflect functional cooperation between different defense systems and to what extent the islands are genomic "sinks" that accumulate diverse nonessential genes, particularly those acquired via horizontal gene transfer. The characteristics of defense islands resemble those of mobilome islands. Defense and mobilome genes are nonrandomly associated in islands, suggesting nonadaptive evolution of the islands via a preferential attachment-like mechanism underpinned by the addictive properties of defense systems such as toxins-antitoxins and an important role of horizontal mobility in the evolution of these islands.

  17. Innovative Adolescent Chemical Dependency Treatment and Its Outcome: A Model Based on Outward Bound Programming.

    Science.gov (United States)

    McPeake, John D.; And Others

    1991-01-01

    Describes adolescent chemical dependency treatment model developed at Beech Hill Hospital (New Hampshire) which integrated Twelve Step-oriented alcohol and drug rehabilitation program with experiential education school, Hurricane Island Outward Bound School. Describes Beech Hill Hurricane Island Outward Bound School Adolescent Chemical Dependency…

  18. 76 FR 28757 - Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense...

    Science.gov (United States)

    2011-05-18

    ... DEPARTMENT OF DEFENSE Office of the Secretary [DOCKET ID DOD-2011-OS-0055] Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense Logistics Agency Actions AGENCY: Defense Logistics Agency, Department of Defense. ACTION: Notice of Availability (NOA) of Revised...

  19. 76 FR 53119 - Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense...

    Science.gov (United States)

    2011-08-25

    ... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2011-OS-0055] Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense Logistics Agency Actions AGENCY: Defense Logistics Agency, Department of Defense. ACTION: Comment Addressed on Notice of...

  20. [Systematically induced effects of Tetranychus cinnabarinus infestation on chemical defense in Zea mays inbred lines].

    Science.gov (United States)

    Zhu, Yu-xi; Yang, Qun-fang; Huang, Yu-bi; Li, Qing

    2015-09-01

    In the present study, we investigated the systematically induced production of defense-related compounds, including DIMBOA, total phenol, trypsin inhibitors (TI) and chymotrypsin inhibitor (CI), by Tetranychus cinnabarinus infestation in Zea mays. The first leaves of two corn in-bred line seedlings, the mite-tolerant line ' H1014168' and the mite-sensitive line 'H1014591', were sucked by T. cinnabarinus adult female for seven days, and then the contents of DIMBOA, total phenol, TI and CI were measured in the second leaf and in the roots, respectively. Results showed that as compared to the unsucked control, all contents of DIMBOA, total phenol, TI and CI induced by T. cinnabarinus sucking were significantly higher in the second leaf of both inbred lines as well as in the roots of the mite-tolerant 'H1014168'. However, in the roots of 'H1014591', these defense compounds had different trends, where there was a higher induction of TI and a lower level of total phenol than that of the healthy control, while had almost no difference in DIMBOA and CI. These findings suggested that the infestation of T. cinnabarinus could systematically induce accumulation of defense-related compounds, and this effect was stronger in the mite-tolerant inbred line than in the mite-sensitive inbred line.

  1. Risk management programs in the chemical industry from Bhopal onward

    International Nuclear Information System (INIS)

    Cramer, J.J.; Greenberg, H.R.

    1992-01-01

    Chemical process safety has long been a consideration in industry but the tragedy at Bhopal in late 1984 resulted in significantly increased attention from industry, government, and the public. Whereas Bhopal had a major effect on regulations in the US, two earlier, highly publicized accidents affected regulations in the United Kingdom and Europe. A 1974 cyclohexane explosion at a chemical manufacturing plant in Flixborough, England, caused a number of fatalities, while a 1976 runaway reaction at a chemical works near Sevesco, Italy, contaminated surrounding farmland and water supplies with dioxin. Although the public's interest can be fickle, the residual concern from all these incidents has been sufficient to affect important regulatory and industry initiatives in the US and abroad. The development of the most important of the US initiatives are reviewed here. Common elements in various process safety management programs are noted and the latest regulatory developments reported. Application can be made to the nuclear industry

  2. 75 FR 76423 - Defense Intelligence Agency National Defense Intelligence College Board of Visitors Closed Meeting

    Science.gov (United States)

    2010-12-08

    ... DEPARTMENT OF DEFENSE Office of the Secretary Defense Intelligence Agency National Defense Intelligence College Board of Visitors Closed Meeting AGENCY: National Defense Intelligence College, Defense Intelligence Agency, Department of Defense. ACTION: Notice of Closed Meeting. SUMMARY: Pursuant to the...

  3. 76 FR 28960 - Defense Intelligence Agency National Defense Intelligence College Board of Visitors Closed Meeting

    Science.gov (United States)

    2011-05-19

    ... DEPARTMENT OF DEFENSE Office of the Secretary Defense Intelligence Agency National Defense Intelligence College Board of Visitors Closed Meeting AGENCY: National Defense Intelligence College, Defense Intelligence Agency, Department of Defense. ACTION: Notice of Closed Meeting. SUMMARY: Pursuant to the...

  4. The Effect of a 12-Week Moderate Intensity Interval Training Program on the Antioxidant Defense Capability and Lipid Profile in Men Smoking Cigarettes or Hookah: A Cohort Study

    Directory of Open Access Journals (Sweden)

    Abdessalem Koubaa

    2015-01-01

    Full Text Available Aim. To examine the impact of interval training program on the antioxidant defense capability and lipid profile in men smoking cigarettes or hookah unable or unwilling to quit smoking. Methods. Thirty-five participants performed an interval training (2 : 1 work : rest ratio 3 times a week for 12 weeks at an intensity of 70% of VO2max. All subjects were subjected to a biochemical test session before and after the training program. Results. The increase of total antioxidant status (TAS, glutathione peroxidase (GPx, and α-tocopherol, is significant only for cigarette smokers (CS and hookah smokers (HS groups. The decrease of malondialdehyde (MDA and the increase of glutathione reductase (GR are more pronounced in smokers groups compared to those of nonsmokers (NS. Superoxide dismutase (SOD increases in NS, CS, and HS groups by 10.1%, 19.5%, and 13.3%, respectively (P<0.001. Likewise, a significant improvement of high-density lipoprotein cholesterol (HDL-C and TC/HDL-C ratio was observed in CS and HS groups (P<0.05. Conclusion. Although the interval training program does not have a significant effect on blood lipid levels, it seems to be very beneficial in the defense and prevention programs of oxidative stress.

  5. Flavan-3-ols Are an Effective Chemical Defense against Rust Infection.

    Science.gov (United States)

    Ullah, Chhana; Unsicker, Sybille B; Fellenberg, Christin; Constabel, C Peter; Schmidt, Axel; Gershenzon, Jonathan; Hammerbacher, Almuth

    2017-12-01

    Phenolic secondary metabolites are often thought to protect plants against attack by microbes, but their role in defense against pathogen infection in woody plants has not been investigated comprehensively. We studied the biosynthesis, occurrence, and antifungal activity of flavan-3-ols in black poplar ( Populus nigra ), which include both monomers, such as catechin, and oligomers, known as proanthocyanidins (PAs). We identified and biochemically characterized three leucoanthocyanidin reductases and two anthocyanidin reductases from P. nigra involved in catalyzing the last steps of flavan-3-ol biosynthesis, leading to the formation of catechin [2,3-trans-(+)-flavan-3-ol] and epicatechin [2,3-cis-(-)-flavan-3-ol], respectively. Poplar trees that were inoculated with the biotrophic rust fungus ( Melampsora larici-populina ) accumulated higher amounts of catechin and PAs than uninfected trees. The de novo-synthesized catechin and PAs in the rust-infected poplar leaves accumulated significantly at the site of fungal infection in the lower epidermis. In planta concentrations of these compounds strongly inhibited rust spore germination and reduced hyphal growth. Poplar genotypes with constitutively higher levels of catechin and PAs as well as hybrid aspen ( Populus tremula × Populus alba ) overexpressing the MYB134 transcription factor were more resistant to rust infection. Silencing PnMYB134 , on the other hand, decreased flavan-3-ol biosynthesis and increased susceptibility to rust infection. Taken together, our data indicate that catechin and PAs are effective antifungal defenses in poplar against foliar rust infection. © 2017 American Society of Plant Biologists. All Rights Reserved.

  6. The Space Nuclear Thermal Propulsion Program: Propulsion for the twenty first century

    International Nuclear Information System (INIS)

    Bleeker, G.; Moody, J.; Kesaree, M.

    1993-01-01

    As mission requirements approach the limits of the chemical propulsion systems, new engines must be investigated that can meet the advanced mission requirements of higher payload fractions, higher velocities, and consequently higher specific Impulses (Isp). The propulsion system that can meet these high demands is a nuclear thermal rocket engine. This engine generates the thrust by expanding/existing the hydrogen, heated from the energy derived from the fission process in a reactor, through a nozzle. The Department of Defense (DoD), however, initiated a new nuclear rocket development program in 1987 for ballistic missile defense application. The Space Nuclear Thermal Propulsion (SNTP) Program that seeks to improve on the technology of ROVER/NERVA grew out of this beginning and has been managed by the Air Force, with the involvement of DoE and NASA. The goal of the SNTP Program is to develop an engine to meet potential Air Force requirements for upper stage engine, bimodal propulsion/power applications, and orbital transfer vehicles, as well as the NASA requirements for possible missions to the Moon and Mars. During the entire life of the program, the DoD has considered safety to be of paramount importance, and is following all national environmental policies

  7. Diet quality can play a critical role in defense efficacy against parasitoids and pathogens in the Glanville fritillary (Melitaea cinxia).

    Science.gov (United States)

    Laurentz, Minna; Reudler, Joanneke H; Mappes, Johanna; Friman, Ville; Ikonen, Suvi; Lindstedt, Carita

    2012-01-01

    Numerous herbivorous insect species sequester noxious chemicals from host plants that effectively defend against predators, and against parasitoids and pathogens. Sequestration of these chemicals may be expensive and involve a trade off with other fitness traits. Here, we tested this hypothesis. We reared Glanville fritillary butterfly (Melitaea cinxia L.) larvae on plant diets containing low- and high-levels of iridoid glycosides (IGs) (mainly aucubin and catalpol) and tested: 1) whether IGs affect the herbivore's defense against parasitoids (measured as encapsulation rate) and bacterial pathogens (measured as herbivore survival); 2) whether parasitoid and bacterial defenses interact; and 3) whether sequestration of the plant's defense chemicals incurs any life history costs. Encapsulation rates were stronger when there were higher percentages of catalpol in the diet. Implanted individuals had greater amounts of IGs in their bodies as adults. This suggests that parasitized individuals may sequester more IGs, increase their feeding rate after parasitism, or that there is a trade off between detoxification efficiency and encapsulation rate. Larval survival after bacterial infection was influenced by diet, but probably not by diet IG content, as changes in survival did not correlate linearly with the levels of IGs in the diet. However, M. cinxia larvae with good encapsulation abilities were better defended against bacteria. We did not find any life history costs of diet IG concentration for larvae. These results suggest that the sequestering of plant defense chemicals can help herbivorous insects to defend against parasitoids.

  8. Transforming Defense

    National Research Council Canada - National Science Library

    Lamb, Christopher J; Bunn, M. E; Lutes, Charles; Cavoli, Christopher

    2005-01-01

    .... Despite the resources and attention consumed by the war on terror, and recent decisions by the White House to curtail the growth of defense spending, the senior leadership of the Department of Defense (DoD...

  9. Computer program for calculation of complex chemical equilibrium compositions and applications. Part 1: Analysis

    Science.gov (United States)

    Gordon, Sanford; Mcbride, Bonnie J.

    1994-01-01

    This report presents the latest in a number of versions of chemical equilibrium and applications programs developed at the NASA Lewis Research Center over more than 40 years. These programs have changed over the years to include additional features and improved calculation techniques and to take advantage of constantly improving computer capabilities. The minimization-of-free-energy approach to chemical equilibrium calculations has been used in all versions of the program since 1967. The two principal purposes of this report are presented in two parts. The first purpose, which is accomplished here in part 1, is to present in detail a number of topics of general interest in complex equilibrium calculations. These topics include mathematical analyses and techniques for obtaining chemical equilibrium; formulas for obtaining thermodynamic and transport mixture properties and thermodynamic derivatives; criteria for inclusion of condensed phases; calculations at a triple point; inclusion of ionized species; and various applications, such as constant-pressure or constant-volume combustion, rocket performance based on either a finite- or infinite-chamber-area model, shock wave calculations, and Chapman-Jouguet detonations. The second purpose of this report, to facilitate the use of the computer code, is accomplished in part 2, entitled 'Users Manual and Program Description'. Various aspects of the computer code are discussed, and a number of examples are given to illustrate its versatility.

  10. Department of Defense Chemical and Biological Defense Programs. Annual Report to Congress 2007

    Science.gov (United States)

    2007-04-01

    Forces medics 3 2 66.7% medical Corps 2,869 1,560 54.4% Dental Corps 740 649 87.7% Veterinary Corps 351 304 86.6% nurse Corps 2,126 1,507 70.9% medical...Detection and Diagnostics Systems GREEN CB.57 nontraditional nerve agent medical Countermeasures GREEN CB.58 Western and eastern equine encephalitis Vaccine...Surface monitoring • analytical methods for the Determination of CW agents • Venezuelan equine encephalitis Vaccine research • Standoff Biological

  11. Home - Defense Technology Security Administration

    Science.gov (United States)

    by @dtsamil Defense Technology Security Administration Mission, Culture, and History Executive Official seal of Defense Technology Security Administration Official seal of Defense Technology Security Administration OFFICE of the SECRETARY of DEFENSE Defense Technology Security Administration

  12. Optimizing Active Cyber Defense

    OpenAIRE

    Lu, Wenlian; Xu, Shouhuai; Yi, Xinlei

    2016-01-01

    Active cyber defense is one important defensive method for combating cyber attacks. Unlike traditional defensive methods such as firewall-based filtering and anti-malware tools, active cyber defense is based on spreading "white" or "benign" worms to combat against the attackers' malwares (i.e., malicious worms) that also spread over the network. In this paper, we initiate the study of {\\em optimal} active cyber defense in the setting of strategic attackers and/or strategic defenders. Specific...

  13. The chemical stockpile intergovernmental consultation program: Lessons for HLW public involvement

    International Nuclear Information System (INIS)

    Feldman, D.L.

    1991-01-01

    This paper assesses the appropriateness of the US Army's Chemical Stockpile Disposal Program's (CSDP) Intergovernmental Consultation and Coordination Boards (ICCBs) as models for incorporating public concerns in the future siting of HLW repositories by DOE. ICCB structure, function, and implementation are examined, along with other issues relevant to the HLW context. 27 refs

  14. Changes in plant defense chemistry (pyrrolizidine alkaloids) revealed through high-resolution spectroscopy

    NARCIS (Netherlands)

    Carvalho, S.; Macel, M.; Schlerf, M.; Eghbali Moghaddam, F.; Mulder, P.P.J.; Skidmore, A.K.; Van der Putten, W.H.

    2013-01-01

    Plant toxic biochemicals play an important role in defense against natural enemies and often are toxic to humans and livestock. Hyperspectral reflectance is an established method for primary chemical detection and could be further used to determine plant toxicity in the field. In order to make a

  15. Program VODAM for treatment of mineral physico-chemical data, with a special application to the uranium case

    International Nuclear Information System (INIS)

    Santoma Juncadella, L.

    1972-01-01

    The VODAM program is written in FORTRAN IV language and makes a physico-chemical analysis of waters, for an element or a number of them, under investigation. A thermodynamical data files is incorporated, and is useful for a low temperature range. It is the basic nucleus for a series of programs of physico-chemical interpretation of hydrogeochemical data and automatic construction of equilibrium diagrams. (Author) 13 refs

  16. The terrorist threat nuclear, radiological, biological, chemical - a medical approach; Menace terroriste nucleaire, radiologique, biologique, chimique - approche medicale

    Energy Technology Data Exchange (ETDEWEB)

    Revel, M.C. de; Gourmelon, M.C.S.; Vidal, P.C.; Renaudeau, P.C.S

    2005-07-01

    Since September 11, 2001, the fear of a large scale nuclear, biological and/or chemical terrorism is taken again into consideration at the highest level of national policies of risk prevention. The advent of international terrorism implies a cooperation between the military defense and the civil defense. The nuclear, radiological, biological and chemical (NRBC) experts of the health service of army and of civil defense will have to work together in case of major terror attack. This book presents this cooperation between civil and military experts in the NRBC domain: risk analysis, national defense plans, crisis management, syndromes and treatments. The different aspects linked with the use of nuclear, biological and chemical weapons are analyzed by the best experts from French medical and research institutes. All topics of each NRBC domain are approached: historical, basic, diagnostic, therapeutic and preventive. (J.S.)

  17. Defense nuclear energy systems selection methodology for civil nuclear power applications

    International Nuclear Information System (INIS)

    Scarborough, J.C.

    1986-01-01

    A methodology developed to select a preferred nuclear power system for a US Department of Defense (DOD) application has been used to evaluate preferred nuclear power systems for a remote island community in Southeast Asia. The plant would provide ∼10 MW of electric power, possibly low-temperature process heat for the local community, and would supplement existing island diesel electric capacity. The nuclear power system evaluation procedure was evolved from a disciplined methodology for ranking ten nuclear power designs under joint development by the US Department of Energy (DOE) and DOD. These included six designs proposed by industry for the Secure Military Power Plant Program (now termed Multimegawatt Terrestrial Reactor Program), the SP-100 Program, the North Warning System Program, and the Modular Advanced High-Temperature Gas-Cooled Reactor (HTGR) and Liquid-Metal Reactor (LMR) programs. The 15 evaluation criteria established for the civil application were generally similar to those developed and used for the defense energy systems evaluation, except that the weighting factor applied to each individual criterion differed. The criteria and their weighting (importance) functions for the civil application are described

  18. Investment in defense and cost of predator-induced defense along a resource gradient

    DEFF Research Database (Denmark)

    Steiner, Uli

    2007-01-01

    An organism's investment in different traits to reduce predation is determined by the fitness benefit of the defense relative to the fitness costs associated with the allocation of time and resources to the defense. Inherent tradeoffs in time and resource allocation should result in differential...... investment in defense along a resource gradient, but competing models predict different patterns of investment. There are currently insufficient empirical data on changes in investment in defensive traits or their costs along resource gradients to differentiate between the competing allocation models....... In this study, I exposed tadpoles to caged predators along a resource gradient in order to estimate investment in defense and costs of defense by assessing predator-induced plasticity. Induced defenses included increased tail depth, reduced feeding, and reduced swimming activity; costs associated...

  19. Unfolding Green Defense

    DEFF Research Database (Denmark)

    Larsen, Kristian Knus

    2015-01-01

    In recent years, many states have developed and implemented green solutions for defense. Building on these initiatives NATO formulated the NATO Green Defence Framework in 2014. The framework provides a broad basis for cooperation within the Alliance on green solutions for defense. This report aims...... to inform and support the further development of green solutions by unfolding how green technologies and green strategies have been developed and used to handle current security challenges. The report, initially, focuses on the security challenges that are being linked to green defense, namely fuel...... consumption in military operations, defense expenditure, energy security, and global climate change. The report then proceeds to introduce the NATO Green Defence Framework before exploring specific current uses of green technologies and green strategies for defense. The report concludes that a number...

  20. Influences on the Timing and Frequency of Cancellations and Truncations of Major Defense Acquisition Programs

    Science.gov (United States)

    2017-03-01

    TPP) when it was judged to be practicable and, when not, a Fixed Price Incentive Fee (FPIF) or Cost Plus Incentive Fee (CPIF) contract. By 1966...left off, he ruled out the use of TPP and discouraged the use of FPIF for development contracts in favor of CPIF. ( Cost Plus Award Fee may not have...CPIF Cost Plus Incentive Fee CY Calendar Year DAB Defense Acquisition Board DAMIR Defense Acquisition Management Information Retrieval DCP

  1. Induction of defensive enzymes (isozymes) during defense against ...

    African Journals Online (AJOL)

    user

    2012-09-06

    Sep 6, 2012 ... defense against two different fungal pathogens in pear calli ... study the biochemical changes in relation to plant defense ... relatively easy to manipulate by empirical means, allowing for a ... earlier phase, and the degree of rot was significantly ..... resistance of fruit, and they play an important role in the.

  2. Minimizing casualties in biological and chemical threats (war and terrorism): the importance of information to the public in a prevention program.

    Science.gov (United States)

    Noy, Shabtai

    2004-01-01

    The most effective means of defending against biological or chemical warfare, whether in war or as a result of terror, is the use of primary prevention. The main goal of such a prevention program is to minimize the human loss by reducing the number of casualties (fatalities, physical wounds, and psychological injury). A secondary objective is to prevent the widespread sense of helplessness in the general population. These two aims complement each other. The more the public is active in defending itself, rather than viewing itself as helpless, the lesser the expected number of casualties of any kind. In order to achieve these two goals, educating the civilian population about risk factors and pointing out appropriate defensive strategies is critical. In the absence of an effective prevention program and active participation by the public, there is a high risk for massive numbers of physical and psychological casualties. An essential ingredient of any preventive program, which ultimately may determine the success or failure of all other protective actions, is early, gradual dissemination of information and guidance to the public, so that citizens can become active participants in the program. The public needs to be given information concerning the nature of the threat and effective methods of coping with it, should an unconventional attack occur. Lack of such adaptive behavior (such as wearing protective gear) is likely to bring about vast numbers of physical and psychological casualties. These large numbers may burden the medical, political, and public safety systems beyond their ability to manage. Failure to provide reasonable prevention and effective interventions can lead to a destruction of the social and emotional fabric of individuals and the society. Furthermore, inadequate preparation, education, and communication can result in the development of damaging mistrust of the political and military leadership, disintegration of social and political structures

  3. LJUNGSKILE 1.0 A Computer Program for Investigation of Uncertainties in Chemical Speciation

    International Nuclear Information System (INIS)

    Ekberg, Christian; Oedegaard-Jensen, Arvid

    2002-11-01

    In analysing the long-term safety of nuclear waste disposal, there is a need to investigate uncertainties in chemical speciation calculations. Chemical speciation is of importance in evaluating the solubility of radionuclides, the chemical degradation of engineering materials, and chemical processes controlling groundwater composition. The uncertainties in chemical speciation may for instance be related to uncertainties in thermodynamic data, the groundwater composition, or the extrapolation to the actual temperature and ionic strength. The magnitude of such uncertainties and its implications are seldom explicitly evaluated in any detail. Commonly available chemical speciation programmes normally do not have a build-in option to include uncertainty ranges. The program developed within this project has the capability of incorporating uncertainty ranges in speciation calculations and can be used for graphical presentation of uncertainty ranges for dominant species. The program should be regarded as a starting point for assessing uncertainties in chemical speciation, since it is not yet comprehensive in its capabilities. There may be limitations in its usefulness to address various geochemical problems. The LJUNGSKILE code allows the user to select two approaches: the Monte Carlo (MC) approach and the Latin Hypercube Sampling (LHS). LHS allows to produce a satisfactory statistics with a minimum of CPU time. It is, in general, possible to do a simple theoretical speciation calculation within seconds. There are, admittedly, alternatives to LHS and there is criticism towards the uncritical use of LHS output because commonly correlation between some of the input variables exists. LHS, like MC, is not capable to take these correlations into account. Such a correlation can, i.e. exist between the pH of a solution and the partial pressure of CO 2 : higher pH solutions may absorb larger amounts of CO 2 and can reduce the CO 2 partial pressure. It is therefore of advantage to

  4. Analytical methods and laboratory facility for the Defense Waste Processing Facility

    International Nuclear Information System (INIS)

    Coleman, C.J.; Dewberry, R.A.; Lethco, A.J.; Denard, C.D.

    1985-01-01

    This paper describes the analytical methods, instruments, and laboratory that will support vitrification of defense waste. The Defense Waste Processing Facility (DWPF) is now being constructed at Savannah River Plant (SRP). Beginning in 1989, SRP high-level defense waste will be immobilized in borosilicate glass for disposal in a federal repository. The DWPF will contain an analytical laboratory for performing process control analyses. Additional analyses will be performed for process history and process diagnostics. The DWPF analytical facility will consist of a large shielded sampling cell, three shielded analytical cells, a laboratory for instrumental analysis and chemical separations, and a counting room. Special instrumentation is being designed for use in the analytical cells, including microwave drying/dissolution apparatus, and remote pipetting devices. The instrumentation laboratory will contain inductively coupled plasma, atomic absorption, Moessbauer spectrometers, a carbon analyzer, and ion chromatography equipment. Counting equipment will include intrinsic germanium detectors, scintillation counters, Phoswich alpha, beta, gamma detectors, and a low-energy photon detector

  5. Arabidopsis flower specific defense gene expression patterns affect resistance to pathogens

    KAUST Repository

    Ederli, Luisa

    2015-02-20

    We investigated whether the Arabidopsis flower evolved protective measures to increase reproductive success. Firstly, analyses of available transcriptome data show that the most highly expressed transcripts in the closed sepal (stage 12) are enriched in genes with roles in responses to chemical stimuli and cellular metabolic processes. At stage 15, there is enrichment in transcripts with a role in responses to biotic stimuli. Comparative analyses between the sepal and petal in the open flower mark an over-representation of transcripts with a role in responses to stress and catalytic activity. Secondly, the content of the biotic defense-associated phytohormone salicylic acid (SA) in sepals and petals is significantly higher than in leaves. To understand whether the high levels of stress responsive transcripts and the higher SA content affect defense, wild-type plants (Col-0) and transgenic plants defective in SA accumulation (nahG) were challenged with the biotrophic fungus Golovinomyces cichoracearum, the causal agent of powdery mildew, and the necrotrophic fungus Botrytis cinerea. NahG leaves were more sensitive than those of Col-0, suggesting that in leaves SA has a role in the defense against biotrophs. In contrast, sepals and petals of both genotypes were resistant to G. cichoracearum, indicating that in the flower, resistance to the biotrophic pathogen is not critically dependent on SA, but likely dependent on the up-regulation of stress-responsive genes. Since sepals and petals of both genotypes are equally susceptible to B. cinerea, we conclude that neither stress-response genes nor increased SA accumulation offers protection against the necrotrophic pathogen. These results are interpreted in the light of the distinctive role of the flower and we propose that in the early stages, the sepal may act as a chemical defense barrier of the developing reproductive structures against biotrophic pathogens.

  6. Defense.gov Special Report: Defense Officials Release Operational Energy

    Science.gov (United States)

    , DOD Operational Energy Strategy DOD's Operational Energy Strategy will guide the Defense Department to operations are among the goals of the Defense Department's operational energy strategy, a senior Pentagon operational energy footprint, experts in solar power, microgrids and "smart" generators recently

  7. 75 FR 52732 - Renewal of Department of Defense Federal Advisory Committee; Missile Defense Advisory Committee

    Science.gov (United States)

    2010-08-27

    ... Committee; Missile Defense Advisory Committee AGENCY: Department of Defense (DoD). ACTION: Renewal of..., the Department of Defense gives notice that it is renewing the charter for the Missile Defense... Director, Missile Defense Agency, independent advice and recommendations on all matters relating to missile...

  8. IMPLEMENTATION OF A SAFETY PROGRAM FOR THE WORK ACCIDENTS’ CONTROL. A CASE STUDY IN THE CHEMICAL INDUSTRY

    Directory of Open Access Journals (Sweden)

    Edison Cesar de Faria Nogueira

    2015-03-01

    Full Text Available This article presents a case study related to the implementation of a Work Safety Program in a chemical industry, based on the Process Safety Program, PSP, of a huge energy company. The research was applied, exploratory, qualitative and with and data collection method through documentary and bibliographical research. There will be presented the main practices adopted in order to make the Safety Program a reality inside a chemical industry, its results and contributions for its better development. This paper proposes the implementation of a Safety Program must be preceded by a diagnosis of occupational safety and health management system and with constant critical analysis in order to make the necessary adjustments.

  9. Changes in plant defense chemistry (pyrrolizidine alkaloids) revealed through high-resolution spectroscopy

    Science.gov (United States)

    Carvalho, Sabrina; Macel, Mirka; Schlerf, Martin; Moghaddam, Fatemeh Eghbali; Mulder, Patrick P. J.; Skidmore, Andrew K.; van der Putten, Wim H.

    2013-06-01

    Plant toxic biochemicals play an important role in defense against natural enemies and often are toxic to humans and livestock. Hyperspectral reflectance is an established method for primary chemical detection and could be further used to determine plant toxicity in the field. In order to make a first step for pyrrolizidine alkaloids detection (toxic defense compound against mammals and many insects) we studied how such spectral data can estimate plant defense chemistry under controlled conditions. In a greenhouse, we grew three related plant species that defend against generalist herbivores through pyrrolizidine alkaloids: Jacobaea vulgaris, Jacobaea erucifolia and Senecio inaequidens, and analyzed the relation between spectral measurements and chemical concentrations using multivariate statistics. Nutrient addition enhanced tertiary-amine pyrrolizidine alkaloids contents of J. vulgaris and J. erucifolia and decreased N-oxide contents in S. inaequidens and J. vulgaris. Pyrrolizidine alkaloids could be predicted with a moderate accuracy. Pyrrolizidine alkaloid forms tertiary-amines and epoxides were predicted with 63% and 56% of the variation explained, respectively. The most relevant spectral regions selected for prediction were associated with electron transitions and Csbnd H, Osbnd H, and Nsbnd H bonds in the 1530 and 2100 nm regions. Given the relatively low concentration in pyrrolizidine alkaloids concentration (in the order of mg g-1) and resultant predictions, it is promising that pyrrolizidine alkaloids interact with incident light. Further studies should be considered to determine if such a non-destructive method may predict changes in PA concentration in relation to plant natural enemies. Spectroscopy may be used to study plant defenses in intact plant tissues, and may provide managers of toxic plants, food industry and multitrophic-interaction researchers with faster and larger monitoring possibilities.

  10. Defense AT and L Magazine. Vol. 42, no. 5, September-October 2013

    Science.gov (United States)

    2013-09-01

    DAU Visual Arts and Press Randy Weekes Defense AT&L Editorial Staff Managing Editor/Senior Editor, DAU Press Benjamin Tyree Online Content Editor... ROAD FT BELVOIR VA 22060-5565 Disclaimer Statements of fact or opinion appearing in Defense AT&L are solely those of the authors and are not nec...programs that we cannot reasonably expect to pay for in the future. The author can be contacted at Chad.Ohlandt@osd.mil. Where Can You Get the Latest

  11. Does chemical aposematic (warning) signaling occur between host plants and their potential parasitic plants?

    Science.gov (United States)

    Lev-Yadun, Simcha

    2013-07-01

    Aposematism (warning) signaling is a common defensive mechanism toward predatory or herbivorous animals, i.e., interactions between different trophic levels. I propose that it should be considered at least as a working hypothesis that chemical aposematism operates between certain host plants and their plant predators, parasitic plants, and that although they are also plants, they belong to a higher trophic level. Specific host plant genotypes emit known repelling chemical signals toward parasitic plants, which reduce the level of, slow the directional parasite growth (attack) toward the signaling hosts, or even cause parasitic plants to grow away from them in response to these chemicals. Chemical host aposematism toward parasitic plants may be a common but overlooked defense from parasitic plants.

  12. 75 FR 59176 - DoD Mandatory Declassification Review (MDR) Program

    Science.gov (United States)

    2010-09-27

    ..., VA 22060-6201. (13) Missile Defense Agency. Missile Defense Agency, Attention: MDA/DS, 7100 Defense... DEPARTMENT OF DEFENSE Office of the Secretary 32 CFR Part 222 [DoD-2010-OS-0043; RIN 0790-AI62] DoD Mandatory Declassification Review (MDR) Program AGENCY: Department of Defense. ACTION: Proposed...

  13. Strategic Framework for the Defense Acquisition System Understanding Defense Consolidation

    National Research Council Canada - National Science Library

    Potts, Anthony W

    2007-01-01

    ...% of defense product sales annually. Defense consolidation has diminished the flexibility required for surge capacity, diminished competitive innovations in products, and reduced competitive pricing based on multiple sources for products...

  14. Confronting actual influence of radiation on human bodies and biological defense mechanism

    International Nuclear Information System (INIS)

    Matsubara, Junko

    2012-01-01

    After the accident at Fukushima Daiichi Nuclear Power Plant of Tokyo Electric Power Company, social, economical, psychological pressures on local residents and fears of radiation among the general public have not been resolved. Based on the assumption that the negligence of specialists to clearly explain the influence of radiation on human bodies to the general public is the factor for above mentioned pressures and fears, the influence of radiation from a realistic view was discussed. The topics covered are: (1) understanding the meaning of radiation regulation, (2) radiation and threshold values, (3) actual influence of low-dose radiation, (4) chemical and biological defense in defense mechanism against radiation, (5) problems raised by Fukushima Daiichi nuclear accident. Furthermore, the article explains the principles and the applications of biological defense function activation, and suggested that self-help efforts to fight against stress are from now on. (S.K.)

  15. How Streptomyces anulatus Primes Grapevine Defenses to Cope with Gray Mold: A Study of the Early Responses of Cell Suspensions

    Directory of Open Access Journals (Sweden)

    Parul Vatsa-Portugal

    2017-06-01

    Full Text Available Gray mold, caused by Botrytis cinerea, is one of the most destructive diseases of grapevine and is controlled with an intense application of fungicides. As alternatives to chemicals, beneficial microbes may promote plant health by stimulating the plant’s immune system. An actinomycete, Streptomyces anulatus S37, has been screened from the rhizosphere microbiome of healthy Vitis vinifera on the basis of its ability to promote grapevine growth and to induce resistance against various phytopathogens, including B. cinerea. However, molecular mechanisms involved locally after direct perception of these bacteria by plant cells still remain unknown. This study focuses on local defense events induced in grapevine cells during interactions with S. anulatus S37 before and after pathogen challenge. We demonstrated that S. anulatus S37 induced early responses including oxidative burst, extracellular alkalinization, activation of protein kinases, induction of defense gene expression and phytoalexin accumulation, but not the programmed cell death. Interestingly, upon challenge with the B. cinerea, the S. anulatus S37 primed grapevine cells for enhanced defense reactions with a decline in cell death. In the presence of the EGTA, a calcium channel inhibitor, the induced oxidative burst, and the protein kinase activity were inhibited, but not the extracellular alkalinization, suggesting that Ca2+ may also contribute upstream to the induced defenses. Moreover, desensitization assays using extracellular pH showed that once increased by S. anulatus S37, cells became refractory to further stimulation by B. cinerea, suggesting that grapevine cells perceive distinctly beneficial and pathogenic microbes.

  16. Defense Acquisitions: Assessments of Selected Weapon Programs

    Science.gov (United States)

    2017-03-01

    Figure 17: Examples of Knowledge Scorecards 61 Page vi GAO-17-333SP Assessments of Selected Weapon Programs...programs. Page 61 GAO-17-333SP Assessments of Selected Weapon Programs Figure 17: Examples of Knowledge Scorecards Pursuant to a...had direct access to the USD AT&L and other senior acquisition officials, and some approval authorities were delegated to lower levels. For example

  17. STIMULATION OF DEFENSE FACTORS FOR OYSTERS DEPLOYED TO CONTAMINATED SITES IN PENSACOLA BAY, FLORIDA

    Science.gov (United States)

    A positive association between chemical contaminants and defense factors has been established for eastern oysters (Crassostrea virginica) from Florida, but it is unknown whether such factors can be stimulated through short-term exposure to contaminants in the field. Hatchery oyst...

  18. Defense waste transportation: cost and logistics studies

    International Nuclear Information System (INIS)

    Andrews, W.B.; Cole, B.M.; Engel, R.L.; Oylear, J.M.

    1982-08-01

    Transportation of nuclear wastes from defense programs is expected to significantly increase in the 1980s and 1990s as permanent waste disposal facilities come into operation. This report uses models of the defense waste transportation system to quantify potential transportation requirements for treated and untreated contact-handled transuranic (CH-TRU) wastes and high-level defense wastes (HLDW). Alternative waste management strategies in repository siting, waste retrieval and treatment, treatment facility siting, waste packaging and transportation system configurations were examined to determine their effect on transportation cost and hardware requirements. All cost estimates used 1980 costs. No adjustments were made for future changes in these costs relative to inflation. All costs are reported in 1980 dollars. If a single repository is used for defense wastes, transportation costs for CH-TRU waste currently in surface storage and similar wastes expected to be generated by the year 2000 were estimated to be 109 million dollars. Recovery and transport of the larger buried volumes of CH-TRU waste will increase CH-TRU waste transportation costs by a factor of 70. Emphasis of truck transportation and siting of multiple repositories would reduce CH-TRU transportation costs. Transportation of HLDW to repositories for 25 years beginning in 1997 is estimated to cost $229 M in 1980 costs and dollars. HLDW transportation costs could either increase or decrease with the selection of a final canister configuration. HLDW transportation costs are reduced when multiple repositories exist and emphasis is placed on truck transport

  19. A truck cask design for shipping defense high-level waste

    International Nuclear Information System (INIS)

    Madsen, M.M.; Zimmer, A.

    1985-01-01

    The Defense High-Level Waste (DHLW) cask is a Type B packaging currently under development by the U.S. Department of Energy (DOE). This truck cask has been designed to initially transport borosilicate glass waste from the Defense Waste Processing Facility (DWPF) to the Waste Isolation Pilot Plant (WIPP). Specific program activities include designing, testing, certifying, and fabricating a prototype legal-weight truck cask system. The design includes such state-of-the-art features as integral impact limiters and remote handling features. A replaceable shielding liner provides the flexibility for shipping a wide range of waste types and activity levels

  20. Strategic Defense Initiative: Splendid Defense or Pipe Dream? Headline Series No. 275.

    Science.gov (United States)

    Armstrong, Scott; Grier, Peter

    This pamphlet presents a discussion of the various components of President Reagan's Strategic Defense Initiative (SDI) including the problem of pulling together various new technologies into an effective defensive system and the politics of the so-called "star wars" system. An important part of the defense initiative is the…

  1. Chemical ecology of the Thysanoptera

    Science.gov (United States)

    Murray S. Blum

    1991-01-01

    The chemical ecology of the Thysanoptera is identified with a variety of natural products discharged in anal droplets during confrontations with adversaries. These exudates are fortified with defensive allomones that may function as repellents, contact irritants, or in some cases, fumigants. Thrips synthesize a large diversity of allomonal products that include...

  2. Testing of the Defense Waste Processing Facility Cold Chemical Dissolution Method in Sludge Batch 9 Qualification

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Pareizs, J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Coleman, C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Young, J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Brown, L. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-05-10

    For each sludge batch that is processed in the Defense Waste Processing Facility (DWPF), the Savannah River National Laboratory (SRNL) tests the applicability of the digestion methods used by the DWPF Laboratory for elemental analysis of Sludge Receipt and Adjustment Tank (SRAT) Receipt samples and SRAT Product process control samples. DWPF SRAT samples are typically dissolved using a method referred to as the DWPF Cold Chemical or Cold Chem Method (CC), (see DWPF Procedure SW4- 15.201). Testing indicates that the CC method produced mixed results. The CC method did not result in complete dissolution of either the SRAT Receipt or SRAT Product with some fine, dark solids remaining. However, elemental analyses did not reveal extreme biases for the major elements in the sludge when compared with analyses obtained following dissolution by hot aqua regia (AR) or sodium peroxide fusion (PF) methods. The CC elemental analyses agreed with the AR and PF methods well enough that it should be adequate for routine process control analyses in the DWPF after much more extensive side-by-side tests of the CC method and the PF method are performed on the first 10 SRAT cycles of the Sludge Batch 9 (SB9) campaign. The DWPF Laboratory should continue with their plans for further tests of the CC method during these 10 SRAT cycles.

  3. Financial Reporting Procedures for Defense Distribution Depots - Defense Logistics Agency Business Area of the Defense Business Operations Fund

    National Research Council Canada - National Science Library

    Young, Shelton

    1994-01-01

    In our audit of the FY 1993 Financial Statements for the Distribution Depots--Defense Logistics Agency Business Mea of the Defense Business Operations Fund, we evaluated procedures and controls used...

  4. Defense styles of pedophilic offenders.

    Science.gov (United States)

    Drapeau, Martin; Beretta, Véronique; de Roten, Yves; Koerner, Annett; Despland, Jean-Nicolas

    2008-04-01

    This pilot study investigated the defense styles of pedophile sexual offenders. Interviews with 20 pedophiles and 20 controls were scored using the Defense Mechanisms Rating Scales. Results showed that pedophiles had a significantly lower overall defensive functioning score than the controls. Pedophiles used significantly fewer obsessional-level defenses but more major image-distorting and action-level defenses. Results also suggested differences in the prevalence of individual defenses where pedophiles used more dissociation, displacement, denial, autistic fantasy, splitting of object, projective identification, acting out, and passive aggressive behavior but less intellectualization and rationalization.

  5. Strategic Framework for the Defense Acquisition System Understanding Defense Consolidation

    National Research Council Canada - National Science Library

    Potts, Anthony W

    2007-01-01

    The 1993 policy to promote the consolidation of the United States defense industry began a series of acquisitions and mergers that went beyond the intent of the policy and left the Department of Defense (DoD...

  6. Recent Advances in Decontamination of Chemical Warfare Agents

    OpenAIRE

    Abdul Wadood Khan; Sabna Kotta; Shahid Husain Ansari; Javed Ali; Rakesh Kumar Sharma

    2013-01-01

    The recent turmoil and volatile situation in many countries and the increased risk of terrorist activities have raised alarm bells for the field of defense against toxic chemical/materials. These situations poses threats to society as terrorists can take advantage of such situations to strike and cause public mayhem. A number of chemicals have the potential of being used as chemical warfare (CW) agents. CW agents could immediately kill or incapacitate the affected individuals even when they a...

  7. Defense and attack of complex and dependent systems

    International Nuclear Information System (INIS)

    Hausken, Kjell

    2010-01-01

    A framework is constructed for how to analyze the strategic defense of an infrastructure subject to attack by a strategic attacker. Merging operations research, reliability theory, and game theory for optimal analytical impact, the optimization program for the defender and attacker is specified. Targets can be in parallel, series, combined series-parallel, complex, k-out-of-n redundancy, independent, interdependent, and dependent. The defender and attacker determine how much to invest in defending versus attacking each of multiple targets. A target can have economic, human, and symbolic values, subjectively assessed by the defender and attacker. A contest success function determines the probability of a successful attack on each target, dependent on the investments by the defender and attacker into each target, and on characteristics of the contest. The defender minimizes the expected damage plus the defense costs. The attacker maximizes the expected damage minus the attack costs. Each agent is concerned about how his investments vary across the targets, and the impact on his utilities. Interdependent systems are analyzed where the defense and attack on one target impacts all targets. Dependent systems are analyzed applying Markov analysis and repeated games where a successful attack on one target in the first period impacts the unit costs of defense and attack, and the contest intensity, for the other target in the second period.

  8. Defense and attack of complex and dependent systems

    Energy Technology Data Exchange (ETDEWEB)

    Hausken, Kjell, E-mail: kjell.hausken@uis.n [Faculty of Social Sciences, University of Stavanger, N-4036 Stavanger (Norway)

    2010-01-15

    A framework is constructed for how to analyze the strategic defense of an infrastructure subject to attack by a strategic attacker. Merging operations research, reliability theory, and game theory for optimal analytical impact, the optimization program for the defender and attacker is specified. Targets can be in parallel, series, combined series-parallel, complex, k-out-of-n redundancy, independent, interdependent, and dependent. The defender and attacker determine how much to invest in defending versus attacking each of multiple targets. A target can have economic, human, and symbolic values, subjectively assessed by the defender and attacker. A contest success function determines the probability of a successful attack on each target, dependent on the investments by the defender and attacker into each target, and on characteristics of the contest. The defender minimizes the expected damage plus the defense costs. The attacker maximizes the expected damage minus the attack costs. Each agent is concerned about how his investments vary across the targets, and the impact on his utilities. Interdependent systems are analyzed where the defense and attack on one target impacts all targets. Dependent systems are analyzed applying Markov analysis and repeated games where a successful attack on one target in the first period impacts the unit costs of defense and attack, and the contest intensity, for the other target in the second period.

  9. Recognizing Plant Defense Priming

    NARCIS (Netherlands)

    Martinez-Medina, Ainhoa; Flors, Victor; Heil, Martin; Mauch-Mani, Brigitte; Pieterse, Corné M J|info:eu-repo/dai/nl/113115113; Pozo, Maria J; Ton, Jurriaan; van Dam, Nicole M; Conrath, Uwe

    2016-01-01

    Defense priming conditions diverse plant species for the superinduction of defense, often resulting in enhanced pest and disease resistance and abiotic stress tolerance. Here, we propose a guideline that might assist the plant research community in a consistent assessment of defense priming in

  10. Recognizing plant defense priming

    NARCIS (Netherlands)

    Martinez-Medina, A.; Flors, V.; Heil, M.; Mauch-Mani, B.; Pieterse, C.M.J.; Pozo, M.J.; Ton, J.; Van Dam, N.M.; Conrath, U.

    2016-01-01

    Defense priming conditions diverse plant species for the superinduction of defense, often resulting in enhanced pest and disease resistance and abiotic stress tolerance. Here, we propose a guideline that might assist the plant research community in a consistent assessment of defense priming in

  11. Tools and benefits of „Partnership for Peace” program for the Republic of Moldova

    Directory of Open Access Journals (Sweden)

    Nicolae ŢÂU

    2018-03-01

    Full Text Available The article reviews the tools and mechanisms of the „Partnership for Peace” Program and its benefits for our country. Among the main benefits, the authors mention: reforming the defense and security sector, ensuring the interoperability of its own forces with those of the allied and partner countries with regard to participate in NATO PfP multinational exercises and operations, protecting the environment by destroying and neutralizing expired ammunition stocks, neutralization and disposal of pesticide and chemical stocks.

  12. Surfactin Protects Wheat against Zymoseptoria tritici and Activates Both Salicylic Acid- and Jasmonic Acid-Dependent Defense Responses

    Directory of Open Access Journals (Sweden)

    Geraldine Le Mire

    2018-01-01

    Full Text Available Natural elicitors induce plant resistance against a broad spectrum of diseases, and are currently among the most promising biocontrol tools. The present study focuses on the elicitor properties of the cyclic lipopeptide surfactin on wheat, in order to stimulate the defenses of this major crop against the challenging fungal pathogen Zymoseptoria tritici. The protection efficacy of surfactin extracted from the strain Bacillus amyloliquefaciens S499 was investigated through greenhouse trials. Surfactin protected wheat by 70% against Z. tritici, similarly to the chemical reference elicitor Bion®50WG. In vitro biocidal assays revealed no antifungal activities of surfactin towards the pathogen. A biomolecular RT-qPCR based low-density microarray tool was used to study the relative expression of 23 wheat defense genes. Surfactin significantly induced wheat natural defenses by stimulating both salicylic acid- and jasmonic acid-dependent signaling pathways. Surfactin was successfully tested as an elicitor on the pathosystem wheat–Z. tritici. These results promote further sustainable agricultural practices and the reduction of chemical inputs.

  13. Plant defense against insect herbivores

    DEFF Research Database (Denmark)

    Fürstenberg-Hägg, Joel; Zagrobelny, Mika; Bak, Søren

    2013-01-01

    , defense compounds. These bioactive specialized plant defense compounds may repel or intoxicate insects, while defense proteins often interfere with their digestion. Volatiles are released upon herbivory to repel herbivores, attract predators or for communication between leaves or plants, and to induce......Plants have been interacting with insects for several hundred million years, leading to complex defense approaches against various insect feeding strategies. Some defenses are constitutive while others are induced, although the insecticidal defense compound or protein classes are often similar...... defense responses. Plants also apply morphological features like waxes, trichomes and latices to make the feeding more difficult for the insects. Extrafloral nectar, food bodies and nesting or refuge sites are produced to accommodate and feed the predators of the herbivores. Meanwhile, herbivorous insects...

  14. Military Construction of the Defense Finance and Accounting Service Operations Facility, Columbus, Ohio

    National Research Council Canada - National Science Library

    Granetto, Paul

    1995-01-01

    The audit objectives were to determine whether the Defense Finance and Accounting Service Columbus Center properly planned and programmed the FY 1996 proposed military construction project and whether...

  15. Sociocultural Behavior Research and Engineering in the Department of Defense Context

    Science.gov (United States)

    2011-09-01

    sponsored by the Incisive Analysis Office is Socio-cultural Content in Language ( SCIL ). SCIL explores and develops novel designs, algorithms, methods...to meet the grand challenge of shaping the future force. DLO and programs such as IARPA’s SCIL are important for addressing persisting gaps in...programs conducting research relevant to building defense-related capabilities in sociocultural behavior. The Socio-Cultural Content in Language ( SCIL

  16. Other Defense Organizations and Defense Finance and Accounting Service Controls Over High-Risk Transactions Were Not Effective

    Science.gov (United States)

    2016-03-28

    Defense Organizations and Defense Finance and Accounting Service Controls Over High-Risk Transactions Were Not Effective M A R C H 2 8 , 2 0 1 6...Defense Organizations and Defense Finance and Accounting Service Controls Over High-Risk Transactions Were Not Effective Visit us at www.dodig.mil... FINANCE AND ACCOUNTING SERVICE DIRECTOR, DEFENSE HEALTH AGENCY SUBJECT: Other Defense Organizations and Defense Finance and Accounting Service

  17. Silverleaf Whitefly Induces Salicylic Acid Defenses and Suppresses Effectual Jasmonic Acid Defenses1[W][OA

    Science.gov (United States)

    Zarate, Sonia I.; Kempema, Louisa A.; Walling, Linda L.

    2007-01-01

    The basal defenses important in curtailing the development of the phloem-feeding silverleaf whitefly (Bemisia tabaci type B; SLWF) on Arabidopsis (Arabidopsis thaliana) were investigated. Sentinel defense gene RNAs were monitored in SLWF-infested and control plants. Salicylic acid (SA)-responsive gene transcripts accumulated locally (PR1, BGL2, PR5, SID2, EDS5, PAD4) and systemically (PR1, BGL2, PR5) during SLWF nymph feeding. In contrast, jasmonic acid (JA)- and ethylene-dependent RNAs (PDF1.2, VSP1, HEL, THI2.1, FAD3, ERS1, ERF1) were repressed or not modulated in SLWF-infested leaves. To test for a role of SA and JA pathways in basal defense, SLWF development on mutant and transgenic lines that constitutively activate or impair defense pathways was determined. By monitoring the percentage of SLWF nymphs in each instar, we show that mutants that activate SA defenses (cim10) or impair JA defenses (coi1) accelerated SLWF nymphal development. Reciprocally, mutants that activate JA defenses (cev1) or impair SA defenses (npr1, NahG) slowed SLWF nymphal development. Furthermore, when npr1 plants, which do not activate downstream SA defenses, were treated with methyl jasmonate, a dramatic delay in nymph development was observed. Collectively, these results showed that SLWF-repressed, JA-regulated defenses were associated with basal defense to the SLWF. PMID:17189328

  18. Proceedings, Conference on the Defense Planning, Programming, and Budgeting System (PPBS): Past, Present, and Future Held at Washington, DC on 4-6 November 1982

    Science.gov (United States)

    1982-11-06

    They are reviewed by the Deputy Chief of Staff for Installations and Logistics to de - The DC/S for manpower then goes on to a termine the logistica ...analyses have manages its programming process. concentrated on such innovations as the De - fense Resources Board and Defense Guidance. * Discussions of... transport that fighting force to the every student of any kind of management at all beach or into battle, then all of General would say that if you

  19. Rethinking Defensive Information Warfare

    National Research Council Canada - National Science Library

    French, Geoffrey S

    2004-01-01

    .... This paper examines defensive tactics and strategies from the German defense in depth that emerged from World War I to the American Active Defense that developed in the Cold War and proposes a new mindset for DIW that draws on these operational concepts from military history.

  20. Defense Threat Reduction Agency > Careers > Onboarding > Special Programs

    Science.gov (United States)

    Development Work/Life Programs Onboarding Onboarding Overview Before You Report Sponsor Program Getting Here , programs, and practices to help our employees and Service members balance work and family responsibilities . We have put in place family-friendly Work/Life programs and policies designed to create a more

  1. ISTEF Laser Radar Program

    National Research Council Canada - National Science Library

    Stryjewski, John

    1998-01-01

    The BMDO Innovative Science and Technology Experimentation Facility (BMDO/ISTEF) laser radar program is engaged in an ongoing program to develop and demonstrate advanced laser radar concepts for Ballistic Missile Defense (BMD...

  2. NVLAP activities at Department of Defense calibration laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Schaeffer, D.M. [Defense Nuclear Agency, Alexandria, VA (United States)

    1993-12-31

    There are 367 active radiological instrument calibration laboratories within the U.S. Department of Defense (DoD). Each of the four services in DoD manages, operates, and certifies the technical proficiency and competency of those laboratories under their cognizance. Each service has designated secondary calibration laboratories to trace all calibration source standards to the National Institute of Standards and Technology. Individual service radiological calibration programs and capabilities, present and future, are described, as well as the measurement quality assurance (MQA) processes for their traceability. National Voluntary Laboratory Accreditation Program (NVLAP) programs for dosimetry systems are briefly summarized. Planned NVLAP accreditation of secondary laboratories is discussed in the context of current technical challenges and future efforts.

  3. NVLAP activities at Department of Defense calibration laboratories

    International Nuclear Information System (INIS)

    Schaeffer, D.M.

    1993-01-01

    There are 367 active radiological instrument calibration laboratories within the U.S. Department of Defense (DoD). Each of the four services in DoD manages, operates, and certifies the technical proficiency and competency of those laboratories under their cognizance. Each service has designated secondary calibration laboratories to trace all calibration source standards to the National Institute of Standards and Technology. Individual service radiological calibration programs and capabilities, present and future, are described, as well as the measurement quality assurance (MQA) processes for their traceability. National Voluntary Laboratory Accreditation Program (NVLAP) programs for dosimetry systems are briefly summarized. Planned NVLAP accreditation of secondary laboratories is discussed in the context of current technical challenges and future efforts

  4. 75 FR 65462 - Renewal of Department of Defense Federal Advisory Committee; Department of Defense Military...

    Science.gov (United States)

    2010-10-25

    ... Committee; Department of Defense Military Family Readiness Council AGENCY: Department of Defense (DoD... renewing the charter for the Department of Defense Military Family Readiness Council (hereafter referred to... requirements for the support of military family readiness by the Department of Defense; and (c) evaluate and...

  5. A Benzothiadiazole Primes Parsley Cells for Augmented Elicitation of Defense Responses

    Science.gov (United States)

    Katz, Vera A.; Thulke, Oliver U.; Conrath, Uwe

    1998-01-01

    Systemic acquired resistance is an important component of the disease-resistance arsenal of plants, and is associated with an enhanced potency for activating local defense responses upon pathogen attack. Here we demonstrate that pretreatment with benzothiadiazole (BTH), a synthetic activator of acquired resistance in plants, augmented the sensitivity for low-dose elicitation of coumarin phytoalexin secretion by cultured parsley (Petroselinum crispum L.) cells. Enhanced coumarin secretion was associated with potentiated activation of genes encoding Phe ammonia-lyase (PAL). The augmentation of PAL gene induction was proportional to the length of pretreatment with BTH, indicating time-dependent priming of the cells. In contrast to the PAL genes, those for anionic peroxidase were directly induced by BTH in the absence of elicitor, thus confirming a dual role for BTH in the activation of plant defenses. Strikingly, the ability of various chemicals to enhance plant disease resistance correlated with their capability to potentiate parsley PAL gene elicitation, emphasizing an important role for defense response potentiation in acquired plant disease resistance. PMID:9701589

  6. 76 FR 45542 - Strategic Environmental Research and Development Program (SERDP), Scientific Advisory Board

    Science.gov (United States)

    2011-07-29

    ... DEPARTMENT OF DEFENSE Office of the Secretary Strategic Environmental Research and Development Program (SERDP), Scientific Advisory Board AGENCY: Office of the Secretary, Department of Defense. ACTION... program areas. These projects are requesting Strategic Environmental Research and Development Program...

  7. MicroRNA-Mediated Gene Silencing in Plant Defense and Viral Counter-Defense

    Directory of Open Access Journals (Sweden)

    Sheng-Rui Liu

    2017-09-01

    Full Text Available MicroRNAs (miRNAs are non-coding RNAs of approximately 20–24 nucleotides in length that serve as central regulators of eukaryotic gene expression by targeting mRNAs for cleavage or translational repression. In plants, miRNAs are associated with numerous regulatory pathways in growth and development processes, and defensive responses in plant–pathogen interactions. Recently, significant progress has been made in understanding miRNA-mediated gene silencing and how viruses counter this defense mechanism. Here, we summarize the current knowledge and recent advances in understanding the roles of miRNAs involved in the plant defense against viruses and viral counter-defense. We also document the application of miRNAs in plant antiviral defense. This review discusses the current understanding of the mechanisms of miRNA-mediated gene silencing and provides insights on the never-ending arms race between plants and viruses.

  8. Recognizing Plant Defense Priming.

    Science.gov (United States)

    Martinez-Medina, Ainhoa; Flors, Victor; Heil, Martin; Mauch-Mani, Brigitte; Pieterse, Corné M J; Pozo, Maria J; Ton, Jurriaan; van Dam, Nicole M; Conrath, Uwe

    2016-10-01

    Defense priming conditions diverse plant species for the superinduction of defense, often resulting in enhanced pest and disease resistance and abiotic stress tolerance. Here, we propose a guideline that might assist the plant research community in a consistent assessment of defense priming in plants. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. In Defense of Societal Issues as Organizers for School Science.

    Science.gov (United States)

    Yager, Robert E.

    1983-01-01

    Offers a defense of societal issues as organizers for school science programs in response to criticisms of this thesis discussed in SE 534 649. Indicates that there appears to be no evidence that using nontraditional topics as organizers will make science more subject to manipulation and perversion. (JN)

  10. BombCAD - A new tool for bomb defense in nuclear facilities

    International Nuclear Information System (INIS)

    Massa, D.J.; Howard, J.W.; Sturm, S.R.

    1988-01-01

    This paper describes a new tool for analysis of the specific vulnerability of diverse facilites to bomb attack and for computer-aided-design (CAD) of siting, screening and hardening/softening aspects of comprehensive bomb defense programs. BombCAD combines the extensive architectural and engineering data base and graphics capabilities of modern architectural CAD systems with the bomb effects computational capability of the ''SECUREPLAN'' BOMB UTILITY. BombCAD permits architects/engineers, security professionals and facility managers to analytically estimate and graphically display facility vulnerability and changes (reductions) in vulnerability which result from the adoption of various bomb defense measures

  11. Defense Islands in Bacterial and Archaeal Genomes and Prediction of Novel Defense Systems ▿†‡

    Science.gov (United States)

    Makarova, Kira S.; Wolf, Yuri I.; Snir, Sagi; Koonin, Eugene V.

    2011-01-01

    The arms race between cellular life forms and viruses is a major driving force of evolution. A substantial fraction of bacterial and archaeal genomes is dedicated to antivirus defense. We analyzed the distribution of defense genes and typical mobilome components (such as viral and transposon genes) in bacterial and archaeal genomes and demonstrated statistically significant clustering of antivirus defense systems and mobile genes and elements in genomic islands. The defense islands are enriched in putative operons and contain numerous overrepresented gene families. A detailed sequence analysis of the proteins encoded by genes in these families shows that many of them are diverged variants of known defense system components, whereas others show features, such as characteristic operonic organization, that are suggestive of novel defense systems. Thus, genomic islands provide abundant material for the experimental study of bacterial and archaeal antivirus defense. Except for the CRISPR-Cas systems, different classes of defense systems, in particular toxin-antitoxin and restriction-modification systems, show nonrandom clustering in defense islands. It remains unclear to what extent these associations reflect functional cooperation between different defense systems and to what extent the islands are genomic “sinks” that accumulate diverse nonessential genes, particularly those acquired via horizontal gene transfer. The characteristics of defense islands resemble those of mobilome islands. Defense and mobilome genes are nonrandomly associated in islands, suggesting nonadaptive evolution of the islands via a preferential attachment-like mechanism underpinned by the addictive properties of defense systems such as toxins-antitoxins and an important role of horizontal mobility in the evolution of these islands. PMID:21908672

  12. Japan's shift to a proactive defense architecture: Challenges faced by industry, government, and society

    OpenAIRE

    Chung, Hoyoon

    2017-01-01

    Approved for public release; distribution is unlimited As a result of the changing security environment in the Asia-Pacific, Japan is shifting to a more proactive defense policy, as outlined in the National Defense Program Guidelines (NDPG). This thesis investigates the challenges faced by Japan's industry, government, and society in meeting the NDPG objectives. To do this, this thesis probes the following problem areas: difficulties with indigenous production of weapons systems, inability...

  13. Defense AT and L. Volume 45, Issue 1

    Science.gov (United States)

    2016-02-01

    and failures that occur while pursuing an inter- national defense contract. Maritime Autonomy Reducing the Risk in a High-Risk Program David...technical, contractual or financial and administrative data. Driving Future Change With Army Research, Collaboration and Prototyping Jeffrey D. From...situations. The move toward more automation or autonomy in many systems requires that we pay even more attention to the user interface than ever to

  14. Quality assurance in Hanford site defense waste operations

    International Nuclear Information System (INIS)

    Wojtasek, R.D.

    1989-01-01

    This paper discusses quality assurance as an integral part of conducting waste management operations. The storage, treatment, and disposal of radioactive and non- radioactive hazardous wastes at Hanford are described. The author reports that quality assurance programs provide confidence that storage, treatment, and disposal facilities and systems perform as intended. Examples of how quality assurance is applied to Hanford defense waste operations are presented

  15. 32 CFR 2004.20 - National Industrial Security Program Operating Manual (NISPOM) [201(a)].

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false National Industrial Security Program Operating... Defense INFORMATION SECURITY OVERSIGHT OFFICE, NATIONAL ARCHIVES AND RECORDS ADMINISTRATION NATIONAL INDUSTRIAL SECURITY PROGRAM DIRECTIVE NO. 1 Operations § 2004.20 National Industrial Security Program...

  16. Department of Defense Chemical and Biological Defense Program. Volume 1: Annual Report to Congress

    Science.gov (United States)

    2003-04-01

    Albuquerque Operations Office at Kirtland AFB, New Mexico , conducts a Radiological Emergency Team Operations Course; Radiological Emer- gency Medical...Nevada, and Kirtland Air Force Base, New Mexico . • MARFORPAC sponsored a force protection initiative funded by DTRA. DTRA will conduct an independent...strains and isolates from camelpox, cowpox, ectromelia, gerbilpox, Herpes, monkeypox, myxoma, rabbitpox, raccoonpox, skunkpox, vaccinia and varicella

  17. Evaluation of the Defense Contract Audit Agency Audit Coverage of Tricare Contracts

    National Research Council Canada - National Science Library

    Brannin, Patricia

    2000-01-01

    Our objective was to evaluate the adequacy of the Defense Contract Audit Agency (DCAA) audit coverage of contracts for health care provided under TRICARE and the former Civilian Health Care and Medical Program of the Uniformed Services...

  18. A System Analysis of the Recruitment and Retention Problems Associated with the Program Manager for Chemical Demilitarization Organization

    National Research Council Canada - National Science Library

    Gottschalk, Laurence

    2001-01-01

    The primary purpose of this thesis is to investigate the problems of retaining qualified personnel in the Program Manager for Chemical Demilitarization organization through the end date of the program...

  19. Planetary Defense

    Science.gov (United States)

    2016-05-01

    4 Abstract Planetary defense against asteroids should be a major concern for every government in the world . Millions of asteroids and...helps make Planetary Defense viable because defending the Earth against asteroids benefits from all the above technologies. So if our planet security...information about their physical characteristics so we can employ the right strategies. It is a crucial difference if asteroids are made up of metal

  20. User's manual of BISHOP. A Bi-Phase, Sodium-Hydrogen-Oxygen system, chemical equilibrium calculation program

    International Nuclear Information System (INIS)

    Okano, Yasushi; Yamaguchi, Akira

    2001-07-01

    In an event of sodium leakage in liquid metal fast breeder reactors, liquid sodium flows out of piping, and droplet combustion might occur under a certain environmental condition. The combustion heat and reaction products should be evaluated in the sodium fire analysis codes for investigating the influence of the sodium leak age and fire incident. In order to analyze the reaction heat and products, the multi-phase chemical equilibrium calculation program for a sodium, oxygen and hydrogen system has been developed. The developed numerical program is named BISHOP, which denotes 'Bi-Phase, Sodium-Hydrogen-Oxygen, Chemical Equilibrium Calculation Program'. The Gibbs free energy minimization method is used because of the following advantages. Chemical species are easily added and changed. A variety of thermodynamic states, such as isothermal and isentropic changes, can be dealt with in addition to constant temperature and pressure processes. In applying the free energy minimization method to solve the multi-phase sodium reaction system, three new numerical calculation techniques are developed. One is theoretical simplification of phase description in equation system, the other is to extend the Gibbs free energy minimization method to a multi-phase system, and the last is to establish the efficient search for the minimum value. The reaction heat and products at the equilibrium state can be evaluated from the initial conditions, such as temperature, pressure and reactants, using BISHOP. This report describes the thermochemical basis of chemical equilibrium calculations, the system of equations, simplification models, and the procedure to prepare input data and usage of BISHOP. (author)

  1. Ensuring a Strong U.S. Defense for the Future: The National Defense Panel Review of the 2014 Quadrennial Defense Review

    Science.gov (United States)

    2014-07-31

    territorial disputes with China. We note recent moves to station U.S. forces in Darwin , the plan to station a number of Littoral Combat Ships in Singapore...Under Secretary of Defense, Comptroller (C) Charles “Chuck” Hagel Secretary of Defense Mara Karlin Principal Director for Strategy, Policy (P...Support Staff to the Panel Charles Arnold George Sinks U.S. Government Liaison Officers Lori Abele Chief of Staff, Deputy Under Secretary of Defense

  2. Release mitigation spray safety systems for chemical demilitarization applications.

    Energy Technology Data Exchange (ETDEWEB)

    Leonard, Jonathan; Tezak, Matthew Stephen; Brockmann, John E.; Servantes, Brandon; Sanchez, Andres L.; Tucker, Mark David; Allen, Ashley N.; Wilson, Mollye C.; Lucero, Daniel A.; Betty, Rita G.

    2010-06-01

    Sandia National Laboratories has conducted proof-of-concept experiments demonstrating effective knockdown and neutralization of aerosolized CBW simulants using charged DF-200 decontaminant sprays. DF-200 is an aqueous decontaminant, developed by Sandia National Laboratories, and procured and fielded by the US Military. Of significance is the potential application of this fundamental technology to numerous applications including mitigation and neutralization of releases arising during chemical demilitarization operations. A release mitigation spray safety system will remove airborne contaminants from an accidental release during operations, to protect personnel and limit contamination. Sandia National Laboratories recently (November, 2008) secured funding from the US Army's Program Manager for Non-Stockpile Chemical Materials Agency (PMNSCMA) to investigate use of mitigation spray systems for chemical demilitarization applications. For non-stockpile processes, mitigation spray systems co-located with the current Explosive Destruction System (EDS) will provide security both as an operational protective measure and in the event of an accidental release. Additionally, 'tented' mitigation spray systems for native or foreign remediation and recovery operations will contain accidental releases arising from removal of underground, unstable CBW munitions. A mitigation spray system for highly controlled stockpile operations will provide defense from accidental spills or leaks during routine procedures.

  3. Technologies for distributed defense

    Science.gov (United States)

    Seiders, Barbara; Rybka, Anthony

    2002-07-01

    For Americans, the nature of warfare changed on September 11, 2001. Our national security henceforth will require distributed defense. One extreme of distributed defense is represented by fully deployed military troops responding to a threat from a hostile nation state. At the other extreme is a country of 'citizen soldiers', with families and communities securing their common defense through heightened awareness, engagement as good neighbors, and local support of and cooperation with local law enforcement, emergency and health care providers. Technologies - for information exploitation, biological agent detection, health care surveillance, and security - will be critical to ensuring success in distributed defense.

  4. Patriot/Medium Extended Air Defense System Combined Aggregate Program (Patriot/MEADS CAP)

    Science.gov (United States)

    2013-12-01

    SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION /AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY...States, Germany, and Italy to replace the U.S. Patriot air defense systems, Patriot and Hawk systems in Germany, and the Nike system in Italy. The MEADS...combat demonstrated capability against these threats. MEADS will employ a netted distributed architecture with modular components to increase

  5. Science and Technology of Nanostructures in the Department of Defense

    International Nuclear Information System (INIS)

    Murday, James S.

    1999-01-01

    The United States Department of Defense maintains a research and development program in nanostructures with special attention to miniaturization of information technology devices, nanostructured materials, and nanobiotechnology for detection of biological agents. This article provides a brief guide to those DoD funding officers and research scientists actively interested in nanostructures

  6. 76 FR 76318 - Defense Federal Acquisition Regulation Supplement; Technical Amendments

    Science.gov (United States)

    2011-12-07

    ... Defense Business Transformation Agency Contracting Office. PART 204--ADMINISTRATIVE MATTERS 204.402...) * * * (iii) For special notices for small business events, follow the procedures at PGI 205.207(d)(ii). PART... Economy Act order. PART 219--SMALL BUSINESS PROGRAMS 0 22. Section 219.202-1 is added to read as follows...

  7. The 'secureplan' bomb utility: A PC-based analytic tool for bomb defense

    International Nuclear Information System (INIS)

    Massa, R.J.

    1987-01-01

    This paper illustrates a recently developed, PC-based software system for simulating the effects of an infinite variety of hypothetical bomb blasts on structures and personnel in the immediate vicinity of such blasts. The system incorporates two basic rectangular geometries in which blast assessments can be made - an external configuration (highly vented) and an internal configuration (vented and unvented). A variety of explosives can be used - each is translated to an equivalent TNT weight. Provisions in the program account for bomb cases (person, satchel, case and vehicle), mixes of explosives and shrapnel aggregates and detonation altitudes. The software permits architects, engineers, security personnel and facility managers, without specific knowledge of explosives, to incorporate realistic construction hardening, screening programs, barriers and stand-off provisions in the design and/or operation of diverse facilities. System outputs - generally represented as peak incident or reflected overpressure or impulses - are both graphic and analytic and integrate damage threshold data for common construction materials including window glazing. The effects of bomb blasts on humans is estimated in terms of temporary and permanent hearing damage, lung damage (lethality) and whole body translation injury. The software system has been used in the field in providing bomb defense services to a number of commercial clients since July of 1986. In addition to the design of siting, screening and hardening components of bomb defense programs, the software has proven very useful in post-incident analysis and repair scenarios and as a teaching tool for bomb defense training

  8. DEFENSE-ATTACK INTERACTION OVER OPTIMALLY DESIGNED DEFENSE SYSTEMS VIA GAMES AND RELIABILITY

    Directory of Open Access Journals (Sweden)

    Isis Didier Lins

    2014-05-01

    Full Text Available This paper analyzes defense systems taking into account the strategic interactions between two rational agents; one of them is interested in designing a defense system against purposeful attacks of the other. The interaction is characterized by a sequential game with perfect and complete information. Reliability plays a fundamental role in both defining agents' actions and in measuring performance of the defense system for which a series-parallel configuration is set up by the defender. The attacker, in turn, focuses on only one defense subsystem in order to maximize her efficiency in attacking. An algorithm involving backward induction is developed to determine the equilibrium paths of the game. Application examples are also provided.

  9. Does investment in leaf defenses drive changes in leaf economic strategy? A focus on whole-plant ontogeny.

    Science.gov (United States)

    Mason, Chase M; Donovan, Lisa A

    2015-04-01

    Leaf defenses have long been studied in the context of plant growth rate, resource availability, and optimal investment theory. Likewise, one of the central modern paradigms of plant ecophysiology, the leaf economics spectrum (LES), has been extensively studied in the context of these factors across ecological scales ranging from global species data sets to temporal shifts within individuals. Despite strong physiological links between LES strategy and leaf defenses in structure, function, and resource investment, the relationship between these trait classes has not been well explored. This study investigates the relationship between leaf defenses and LES strategy across whole-plant ontogeny in three diverse Helianthus species known to exhibit dramatic ontogenetic shifts in LES strategy, focusing primarily on physical and quantitative chemical defenses. Plants were grown under controlled environmental conditions and sampled for LES and defense traits at four ontogenetic stages. Defenses were found to shift strongly with ontogeny, and to correlate strongly with LES strategy. More advanced ontogenetic stages with more conservative LES strategy leaves had higher tannin activity and toughness in all species, and higher leaf dry matter content in two of three species. Modeling results in two species support the conclusion that changes in defenses drive changes in LES strategy through ontogeny, and in one species that changes in defenses and LES strategy are likely independently driven by ontogeny. Results of this study support the hypothesis that leaf-level allocation to defenses might be an important determinant of leaf economic traits, where high investment in defenses drives a conservative LES strategy.

  10. Managing Complex Programs in a Post-LSI Environment

    National Research Council Canada - National Science Library

    Mockensturm, Jeffery J

    2008-01-01

    .... External forces played a major role in the evolution of these practices: A defense procurement holiday throughout the 1990s significantly reduced defense procurement spending and commensurate programs to manage...

  11. Invasive Egg Predators and Food Availability Interactively Affect Maternal Investment in Egg Chemical Defense

    Directory of Open Access Journals (Sweden)

    Sarah C. Paul

    2018-01-01

    Full Text Available Invasive species commonly predate the offspring of native species and eggs are the life stage most vulnerable to this predation. In many species with no maternal care, females can alter the phenotype of eggs to protect them, for instance through chemical defense. In ladybirds egg alkaloids deter predators, including invasive predatory species of ladybirds, but conversely may attract cannibals who benefit from the consumption of eggs with higher alkaloid levels. Invasive predators tend to be more abundant where resources are also abundant, but in high resource environments the maternal fitness benefits of sibling cannibalism are low. Consequently this presents a conflict for female ladybirds between the different factors that influence egg alkaloid level, as protecting her eggs from predators might come with the cost of inadvertently encouraging within-clutch cannibalism under circumstances where it is not beneficial. We investigated how the ladybird Adalia bipunctata addresses this trade-off experimentally, by measuring the quantity of alkaloids in eggs laid by ladybirds in environments that differed in levels of resource availability and perceived predation risk from an invasive predator Harmonia axyridis. Females did lay eggs with higher egg alkaloid levels under poor resource conditions, but only when predator cues were absent. The resulting negative correlation between egg number and egg alkaloid level under poor resource conditions indicates a trade-off between these two attributes of maternal investment, mediated by female response to offspring predation risk. This implies that selection pressures on mothers to adaptively adjust the risk of siblicide may outweigh the need to protect offspring from interspecific predation. Our results demonstrate that maternal effects are an important aspect of species' responses to invasive predators, and highlight the value of studying maternal effects in the context of the multifaceted environments in

  12. Medical mitigation model: quantifying the benefits of the public health response to a chemical terrorism attack.

    Science.gov (United States)

    Good, Kevin; Winkel, David; VonNiederhausern, Michael; Hawkins, Brian; Cox, Jessica; Gooding, Rachel; Whitmire, Mark

    2013-06-01

    The Chemical Terrorism Risk Assessment (CTRA) and Chemical Infrastructure Risk Assessment (CIRA) are programs that estimate the risk of chemical terrorism attacks to help inform and improve the US defense posture against such events. One aspect of these programs is the development and advancement of a Medical Mitigation Model-a mathematical model that simulates the medical response to a chemical terrorism attack and estimates the resulting number of saved or benefited victims. At the foundation of the CTRA/CIRA Medical Mitigation Model is the concept of stock-and-flow modeling; "stocks" are states that individuals progress through during the event, while "flows" permit and govern movement from one stock to another. Using this approach, the model is able to simulate and track individual victims as they progress from exposure to an end state. Some of the considerations in the model include chemical used, type of attack, route and severity of exposure, response-related delays, detailed treatment regimens with efficacy defined as a function of time, medical system capacity, the influx of worried well individuals, and medical countermeasure availability. As will be demonstrated, the output of the CTRA/CIRA Medical Mitigation Model makes it possible to assess the effectiveness of the existing public health response system and develop and examine potential improvement strategies. Such a modeling and analysis capability can be used to inform first-responder actions/training, guide policy decisions, justify resource allocation, and direct knowledge-gap studies.

  13. AICD -- Advanced Industrial Concepts Division Biological and Chemical Technologies Research Program. 1993 Annual summary report

    Energy Technology Data Exchange (ETDEWEB)

    Petersen, G.; Bair, K.; Ross, J. [eds.

    1994-03-01

    The annual summary report presents the fiscal year (FY) 1993 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program of the Advanced Industrial Concepts Division (AICD). This AICD program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). The annual summary report for 1993 (ASR 93) contains the following: A program description (including BCTR program mission statement, historical background, relevance, goals and objectives), program structure and organization, selected technical and programmatic highlights for 1993, detailed descriptions of individual projects, a listing of program output, including a bibliography of published work, patents, and awards arising from work supported by BCTR.

  14. Workshops on tamper-indicating device (TID) programs and program administration

    International Nuclear Information System (INIS)

    Key, C.; Dickman, D.A.; Amacker, O.P. Jr.

    1996-01-01

    The US/Russia Government-to-Government Cooperative Program for Material Protection, Control and Accounting (MPC and A) was established in an agreement between the Department of Defense of the US and the Ministry of the Russian Federation for Atomic Energy (MINATOM). The goal of this program is to attain certain rapid progress in the improvement of nuclear material protection, control, and accounting in the Russian nuclear complex. One program element of materials control and accounting (MC and A) in the US is the use of tamper-indicating devices (TIDs) as a layer of defense in depth protection against possible theft and/or diversion of nuclear materials. A TID Workshop was developed in the US for implementation throughout Russia as a means for MPC and A. This paper describes the development, implementation, and results to date of the TID Workshops

  15. Defense Leadership and Management Program (DLAMP)

    National Research Council Canada - National Science Library

    Ramp, S

    1997-01-01

    This Directive, under Chapters 23, 33, 41, and 71 of title 5, United States Code, establishes policy and assigns responsibilities for a program of civilian leader training, education, and development...

  16. Defense Nanotechnology Research and Development Program

    National Research Council Canada - National Science Library

    2007-01-01

    ...), Army Research Office (ARO) and the Air Force Office of Scientific Research (AFOSR)initiated numerous research and development programs focusing on advancing science and technology below one micron in size...

  17. Evolution Of The Operational Energy Strategy And Its Consideration In The Defense Acquisition Process

    Science.gov (United States)

    2016-09-01

    Figure 12. PPBE Process Flowchart . Source: AcqNotes (2016). We comment above that once a program manager has completed his major Defense...acquisition system: 1) acquisition, 2) requirements and 3) planning, programming , budgeting, and execution (PPBE). We looked at the evolution of...to gain traction or improve promulgation of key guidance and documentation for new-starts and/or upgrades to weapon system acquisition programs

  18. Pine Defensive Monoterpene α-Pinene Influences the Feeding Behavior of Dendroctonus valens and Its Gut Bacterial Community Structure

    Directory of Open Access Journals (Sweden)

    Letian Xu

    2016-11-01

    Full Text Available The exposure to plant defense chemicals has negative effects on insect feeding activity and modifies insect gut microbial community composition. Dendroctonus valens is a very destructive forest pest in China, and harbors a large diversity and abundance of gut microorganisms. Host pine defensive chemicals can protect the pines from attack by the holobiont. In this study, boring length of D. valens feeding on 0 mg/g α-pinene and 9 mg/g α-pinene concentration in phloem media for 6 and 48 h were recorded, and their gut bacterial communities were analyzed in parallel. Nine milligram per gram α-pinene concentration significantly inhibited boring length of D. valens and altered its gut microbial community structure after 6 h. The inhibition of boring length from 9 mg/g α-pinene in diets ceased after 48 h. No significant differences of the bacterial communities were observed between the beetles in 0 and 9 mg/g α-pinene concentration in phloem media after 48 h. Our results showed that the inhibition of the feeding behavior of D. valens and the disturbance to its gut bacterial communities in 9 mg/g α-pinene concentration in phloem media after 6 h were eliminated after 48 h. The resilience of gut bacterial community of D. valens may help the beetle catabolize pine defense chemical.

  19. The US-Russia missile defense dialogue as a factor of the Russian defense policy

    OpenAIRE

    Dmitry Suslov

    2013-01-01

    To a big extent the Russian defense policy and, as a consequence, development of the Russian defense industrial complex, is determined by the prospects of the US missile defense policy and fate of the US-Russia negotiations in this area. As a cooperative solution seems improbable in the observable future, Russia plans to develop certain response measures of military nature, including creation of a new heavy ICBM, and to create its own missile defense by 2015. However, this policy does not see...

  20. Flavan-3-ols Are an Effective Chemical Defense against Rust Infection1[OPEN

    Science.gov (United States)

    Unsicker, Sybille B.; Fellenberg, Christin; Schmidt, Axel

    2017-01-01

    Phenolic secondary metabolites are often thought to protect plants against attack by microbes, but their role in defense against pathogen infection in woody plants has not been investigated comprehensively. We studied the biosynthesis, occurrence, and antifungal activity of flavan-3-ols in black poplar (Populus nigra), which include both monomers, such as catechin, and oligomers, known as proanthocyanidins (PAs). We identified and biochemically characterized three leucoanthocyanidin reductases and two anthocyanidin reductases from P. nigra involved in catalyzing the last steps of flavan-3-ol biosynthesis, leading to the formation of catechin [2,3-trans-(+)-flavan-3-ol] and epicatechin [2,3-cis-(−)-flavan-3-ol], respectively. Poplar trees that were inoculated with the biotrophic rust fungus (Melampsora larici-populina) accumulated higher amounts of catechin and PAs than uninfected trees. The de novo-synthesized catechin and PAs in the rust-infected poplar leaves accumulated significantly at the site of fungal infection in the lower epidermis. In planta concentrations of these compounds strongly inhibited rust spore germination and reduced hyphal growth. Poplar genotypes with constitutively higher levels of catechin and PAs as well as hybrid aspen (Populus tremula × Populus alba) overexpressing the MYB134 transcription factor were more resistant to rust infection. Silencing PnMYB134, on the other hand, decreased flavan-3-ol biosynthesis and increased susceptibility to rust infection. Taken together, our data indicate that catechin and PAs are effective antifungal defenses in poplar against foliar rust infection. PMID:29070515

  1. Missile Defense: LBJ's Bid To Curb Arms Race Gains Support.

    Science.gov (United States)

    Carter, L J

    1967-04-14

    In the article of 31 March on antiballistic missile defense, the last sentence of paragraph 2, p. 1654, should read: "Manpower for producing . . . but the outer limit would be about 200,000, or half the number of contractor employees and civil servants working for NASA at the peak of the Apollo program."

  2. Defense Agency Travel Payments at Defense Finance and Accounting Service Indianapolis Center

    National Research Council Canada - National Science Library

    1997-01-01

    The audit objective was to assess the effectiveness of Defense Finance and Accounting Service Indianapolis Center management controls over payments to Defense agency personnel for temporary duty and local travel...

  3. Impact of defense conversion and US response

    International Nuclear Information System (INIS)

    Montanarelli, N.

    1994-01-01

    Conversion from military to civilian products due to defense conversion after the end of the Cold War takes a long as 20 years. In USA there are over 50 government programs funded to assist in defence conversion. This paper concentrates on the three major programs that will have the greatest impact on the economy, in the framework of the issues and needs of American industry. Federal government and US industry are making a considerable effort to transform how to do business today. One of the most important emerging themes in the federal program is international competitiveness. Large federal expenditures are made to support research and development that will increase productivity, thereby helping industry in global economic competition. This, in turn will play a key role in absorbing a large quantity od resources affected by the end of the Cold War

  4. Proceedings of the Sandia Laboratories workshop on the use of titanate ion exchangers for defense waste management

    International Nuclear Information System (INIS)

    Schwoebel, R.L.; Northrup, C.J.

    1978-01-01

    Abstracts and visual aids from the following talks are presented: removal of radionuclides from Hanford defense waste solutions; waste management programs at Savannah River Plant; application of defense waste decontamination; americium and curium recovery from nuclear waste using inorganic ion exchanger materials; removal of trace 106 Ru in nuclear waste processing; and titanate characterization and consolidation processes. Copies of three memos are included: 90 Sr radiation effects on sodium titanate loaded macroreticular resin; 238 239 Pu content in defense waste; and preparation and physical properties of sodium titanate in ion exchange resin

  5. SELF-DEFENSE IN KARABAKH CONFLICT?

    Directory of Open Access Journals (Sweden)

    Saeed Bagheri

    2015-01-01

    Full Text Available Use of force is one of the principles of international law which has been banned by the UN Charter and modern constitutions. However, since the enforcement of the UN Charter, self-defense has become the preferred excuse for states to justify their use of force. But applying self-defense requires some conditions. Immediacy is one of the important conditions of self-defense. Immediacy defined as the time span between armed attacks and reaction to it, is the main discourse. This condition requires self defense immediately after the armed conflict or during a rational time span since its occurance.In this respect, the emerging Karabakh Conflict between Armenia and Azerbaijan in the 1990s is important. After Armenia’s armed attacks, Azerbaijan has acted within the scope of legitimate self-defense. But in accordance with UN Security Council cease-fire resolution Azerbaijan has suspended its self-defense actions. However, today, still twenty percent of Azerbaijani territory is still under Armenian occupation. Accordingly, after a long time the validity of Azerbaijan’s right to legitimate self-defense is still subject to arguments.In this article, by comparing two different approaches (strict and board interpretation approaches on the temporal link between the measures of self-defense and the armed attacks (immediacy, the temporal link between the self-defense countermeasures of Azerbaijan and armed attacks by Armenia in Karabakh Conflict will be examined.

  6. Commercial nuclear fuel from U.S. and Russian surplus defense inventories: Materials, policies, and market effects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-05-01

    Nuclear materials declared by the US and Russian governments as surplus to defense programs are being converted into fuel for commercial nuclear reactors. This report presents the results of an analysis estimating the market effects that would likely result from current plans to commercialize surplus defense inventories. The analysis focuses on two key issues: (1) the extent by which traditional sources of supply, such as production from uranium mines and enrichment plants, would be displaced by the commercialization of surplus defense inventories or, conversely, would be required in the event of disruptions to planned commercialization, and (2) the future price of uranium considering the potential availability of surplus defense inventories. Finally, the report provides an estimate of the savings in uranium procurement costs that could be realized by US nuclear power generating companies with access to competitively priced uranium supplied from surplus defense inventories.

  7. Commercial nuclear fuel from U.S. and Russian surplus defense inventories: Materials, policies, and market effects

    International Nuclear Information System (INIS)

    1998-05-01

    Nuclear materials declared by the US and Russian governments as surplus to defense programs are being converted into fuel for commercial nuclear reactors. This report presents the results of an analysis estimating the market effects that would likely result from current plans to commercialize surplus defense inventories. The analysis focuses on two key issues: (1) the extent by which traditional sources of supply, such as production from uranium mines and enrichment plants, would be displaced by the commercialization of surplus defense inventories or, conversely, would be required in the event of disruptions to planned commercialization, and (2) the future price of uranium considering the potential availability of surplus defense inventories. Finally, the report provides an estimate of the savings in uranium procurement costs that could be realized by US nuclear power generating companies with access to competitively priced uranium supplied from surplus defense inventories

  8. Evaluation of the Pilot Program for Home School and ChalleNGe Program Recruits

    National Research Council Canada - National Science Library

    Garcia, F

    2001-01-01

    The National Defense Authorization Act for Fiscal Year 1999 (FY 99) directed a 5-year pilot program to treat graduates of home schools and graduates of the National Guard Youth ChalleNGe Program holding General Education Development (GED...

  9. 77 FR 2653 - Defense Federal Acquisition Regulation Supplement; Pilot Program for Acquisition of Military...

    Science.gov (United States)

    2012-01-19

    ... entity referred to in the interim rule is, in essence, the legal entity that signs the contract with the... contractors as defined within the rule and section 866 of the National Defense Authorization Act for Fiscal...

  10. Improving Defense Health Program Medical Research Processes

    Science.gov (United States)

    2017-08-08

    research , including a Business Cell; 87 Research Development, 88 Research Oversight, 89 and Research Compliance offices;90 and the Center...needed for DHP medical research , such as the Army’s Clinical and Translational Research Program Office, 38 the Navy’s Research Methods Training Program... research stated, “key infrastructure for a learning health system will encompass three core elements: data networks, methods , and workforce.” 221

  11. Natural Products from Antarctic Colonial Ascidians of the Genera Aplidium and Synoicum: Variability and Defensive Role

    Directory of Open Access Journals (Sweden)

    Conxita Avila

    2012-08-01

    Full Text Available Ascidians have developed multiple defensive strategies mostly related to physical, nutritional or chemical properties of the tunic. One of such is chemical defense based on secondary metabolites. We analyzed a series of colonial Antarctic ascidians from deep-water collections belonging to the genera Aplidium and Synoicum to evaluate the incidence of organic deterrents and their variability. The ether fractions from 15 samples including specimens of the species A. falklandicum, A. fuegiense, A. meridianum, A. millari and S. adareanum were subjected to feeding assays towards two relevant sympatric predators: the starfish Odontaster validus, and the amphipod Cheirimedon femoratus. All samples revealed repellency. Nonetheless, some colonies concentrated defensive chemicals in internal body-regions rather than in the tunic. Four ascidian-derived meroterpenoids, rossinones B and the three derivatives 2,3-epoxy-rossinone B, 3-epi-rossinone B, 5,6-epoxy-rossinone B, and the indole alkaloids meridianins A–G, along with other minoritary meridianin compounds were isolated from several samples. Some purified metabolites were tested in feeding assays exhibiting potent unpalatabilities, thus revealing their role in predation avoidance. Ascidian extracts and purified compound-fractions were further assessed in antibacterial tests against a marine Antarctic bacterium. Only the meridianins showed inhibition activity, demonstrating a multifunctional defensive role. According to their occurrence in nature and within our colonial specimens, the possible origin of both types of metabolites is discussed.

  12. Economics of defense high-level waste management in the United States

    International Nuclear Information System (INIS)

    Slate, S.C.; McDonell, W.R.

    1987-01-01

    The Department of Energy (DOE) is responsible for managing defense high-level wastes (DHLW) from U.S. defense activities using environmentally safe and cost-effective methods. In parallel with its technical programs, the DOE is performing economic studies to ensure that costs are minimized. To illustrate the cost estimating techniques and to provide a sense of cost magnitude, the DHLW costs for the Savannah River Plant (SRP) are calculated. Since operations at SRP must be optimized within relatively fixed management practices, the estimation of incremental costs is emphasized. Treatment and disposal costs are shown to equally contribute to the incremental cost of almost $400,000/canister

  13. Preserving the ABM treaty: a critique of the Reagan Strategic Defense Initiative

    International Nuclear Information System (INIS)

    Drell, S.D.; Farley, P.J.; Holloway, D.

    1984-01-01

    President Reagan's Strategic Defense Initiative (SDI) proposal for long-term research and development on a leak-proof defense capability conflicts with the past 15 years of Soviet-American strategic relations and arms control negotiations. It represents a unilateral change, and will elicit a Soviet response based on how the Soviets think their own security may be affected. Whether the SDI transcends or enhances defense, it raises basic issues involving the US-Soviet strategic relationship. Emphasizing the central bearing of the Anti-Ballistic Missile (ABM) Treaty of 1972 the author reviews these issues and questions about the technical and strategic grounds of the proposal. Three recommendations are to limit the SDI program to a search for scientific possibilities, to consult with the Soviets on the ABM Treaty, and to recognize that the ABM Treaty will enhance security more than the SDI. 58 references

  14. Synergistic effects of plant defense elicitors and Trichoderma harzianum on enhanced induction of antioxidant defense system in tomato against Fusarium wilt disease.

    Science.gov (United States)

    Zehra, Andleeb; Meena, Mukesh; Dubey, Manish Kumar; Aamir, Mohd; Upadhyay, R S

    2017-11-02

    Plant defense against their pathogens can be induced by a complex network of different inducers. The present study investigates the synergistic effect of Trichoderma harzianum, exogenous salicylic acid (SA) and methyl jasmonate (MeJA) over the response and regulation of the antioxidant defense mechanisms and lipid peroxidation in tomato plants against Fusarium wilt disease. In the present work, tomato plants were infected by Fusarium oxysporum f. sp. lycopersici 3 days after inoculated with T. harzianum and/or sprayed daily for 3 days with chemical inducers (SA and MeJA). Plants were analysed at 0, 24, 48, 72 and 96 h after inoculation with Fusarium oxysporum f. sp. lycopersici. Infection of tomato plants by pathogen led to strong reduction in the dry weight of roots and shoots with the enhanced concentration of H 2 O 2 and varying degree of lipid peroxidation. Concurrently, exogenous SA, when applied with pathogen greatly enhanced H 2 O 2 content as well as activities of antioxidant enzymes except catalase (CAT) and ascorbate peroxidase (APx). The pathogen challenged plants pretreated with T. harzianum and MeJA together exhibited less lipid peroxidation and as well as the elevated level of ascorbic acid and enhanced activities of antioxidant enzymes. All applied treatments protected tomato seedlings against Fusarium wilt disease but the percentage of protection was found higher in plants pretreated with the combination of T. harzianum and chemical inducers.

  15. Defense enzyme responses in dormant wild oat and wheat caryopses challenged with a seed decay pathogen

    Science.gov (United States)

    Seed dormancy and resistance to seed decay organisms are fundamental ecological strategies for weed seed persistence in the weed seed-bank. Seeds have well-established physical, chemical, and biological defense mechanisms that protect their food reserves from decay-inducing organisms and herbivores....

  16. Programming chemical kinetics: engineering dynamic reaction networks with DNA strand displacement

    Science.gov (United States)

    Srinivas, Niranjan

    Over the last century, the silicon revolution has enabled us to build faster, smaller and more sophisticated computers. Today, these computers control phones, cars, satellites, assembly lines, and other electromechanical devices. Just as electrical wiring controls electromechanical devices, living organisms employ "chemical wiring" to make decisions about their environment and control physical processes. Currently, the big difference between these two substrates is that while we have the abstractions, design principles, verification and fabrication techniques in place for programming with silicon, we have no comparable understanding or expertise for programming chemistry. In this thesis we take a small step towards the goal of learning how to systematically engineer prescribed non-equilibrium dynamical behaviors in chemical systems. We use the formalism of chemical reaction networks (CRNs), combined with mass-action kinetics, as our programming language for specifying dynamical behaviors. Leveraging the tools of nucleic acid nanotechnology (introduced in Chapter 1), we employ synthetic DNA molecules as our molecular architecture and toehold-mediated DNA strand displacement as our reaction primitive. Abstraction, modular design and systematic fabrication can work only with well-understood and quantitatively characterized tools. Therefore, we embark on a detailed study of the "device physics" of DNA strand displacement (Chapter 2). We present a unified view of strand displacement biophysics and kinetics by studying the process at multiple levels of detail, using an intuitive model of a random walk on a 1-dimensional energy landscape, a secondary structure kinetics model with single base-pair steps, and a coarse-grained molecular model that incorporates three-dimensional geometric and steric effects. Further, we experimentally investigate the thermodynamics of three-way branch migration. Our findings are consistent with previously measured or inferred rates for

  17. Chromosome-level genome map provides insights into diverse defense mechanisms in the medicinal fungus Ganoderma sinense

    Science.gov (United States)

    Zhu, Yingjie; Xu, Jiang; Sun, Chao; Zhou, Shiguo; Xu, Haibin; Nelson, David R.; Qian, Jun; Song, Jingyuan; Luo, Hongmei; Xiang, Li; Li, Ying; Xu, Zhichao; Ji, Aijia; Wang, Lizhi; Lu, Shanfa; Hayward, Alice; Sun, Wei; Li, Xiwen; Schwartz, David C.; Wang, Yitao; Chen, Shilin

    2015-01-01

    Fungi have evolved powerful genomic and chemical defense systems to protect themselves against genetic destabilization and other organisms. However, the precise molecular basis involved in fungal defense remain largely unknown in Basidiomycetes. Here the complete genome sequence, as well as DNA methylation patterns and small RNA transcriptomes, was analyzed to provide a holistic overview of secondary metabolism and defense processes in the model medicinal fungus, Ganoderma sinense. We reported the 48.96 Mb genome sequence of G. sinense, consisting of 12 chromosomes and encoding 15,688 genes. More than thirty gene clusters involved in the biosynthesis of secondary metabolites, as well as a large array of genes responsible for their transport and regulation were highlighted. In addition, components of genome defense mechanisms, namely repeat-induced point mutation (RIP), DNA methylation and small RNA-mediated gene silencing, were revealed in G. sinense. Systematic bioinformatic investigation of the genome and methylome suggested that RIP and DNA methylation combinatorially maintain G. sinense genome stability by inactivating invasive genetic material and transposable elements. The elucidation of the G. sinense genome and epigenome provides an unparalleled opportunity to advance our understanding of secondary metabolism and fungal defense mechanisms. PMID:26046933

  18. Comparison of radiation and chemical risks

    International Nuclear Information System (INIS)

    Bengtsson, G.

    1988-01-01

    Injury to living cells is caused by mechanisms which in many cases are similar for radiation and chemicals. It is thus not surprising that radiation and many chemicals can cause similar biological effects, e.g. cancer, fetal injury and hereditary disease. Both radiation and chemicals are always found in our environment. One agent may strengthen or weaken the effect of another, be it radiation in combination with chemicals or one chemical with another. The implications of such synergistic or antagonistic effects are discussed. Intricate mechanisms help the body to defend itself against threats to health from radiation and chemicals, even against cancer risks. In a strategy for health, it might be worth to exploit actively these defense mechanisms, in parallel with decreasing the exposures. On particular interest are the large exposures from commonly known sources such as smoking, sun tanning and high fat contents of food. (author)

  19. 78 FR 5781 - Cost-Sharing Rates for Pharmacy Benefits Program of the TRICARE Program

    Science.gov (United States)

    2013-01-28

    ... DEPARTMENT OF DEFENSE Office of the Secretary Cost-Sharing Rates for Pharmacy Benefits Program of... to cost-sharing rates to the TRICARE Pharmacy Benefits Program. SUMMARY: This notice is to advise interested parties of cost-sharing rate change for the Pharmacy Benefits Program. DATES: The cost-sharing...

  20. Chemical profiling of chemical warfare agents for forensic purposes

    NARCIS (Netherlands)

    Noort, D.; Reuver, L.P.J. de; Fidder, A.; Tromp, M.; Verschraagen, M.

    2010-01-01

    A program has been initiated towards the chemical profiling of chemical warfare agents, in order to support forensic investigations towards synthesis routes, production sites and suspect chemical suppliers. Within the first stage of the project various chemical warfare agents (VX, sulfur mustard,

  1. Defense-Related Responses in Fruit of the Nonhost Chili Pepper against Xanthomonas axonopodis pv. glycines Infection

    Directory of Open Access Journals (Sweden)

    Sung Pae Chang

    2016-08-01

    Full Text Available Xanthomonas axonopodis pv. glycines (Xag is a necrotrophic bacterial pathogen of the soybean that causes bacterial pustules and is a nonhost pathogen of the chili pepper. In the current study, chili pepper fruit wound inoculated in planta with Xag 8ra formed necrotic lesions on the fruit surface and induced several structural and chemical barriers systemically in the fruit tissue. The initial defense response included programmed cell death of necrotizing and necrotized cells, which was characterized by nuclear DNA cleavage, as detected by TUNEL-confocal laser scanning microscopy (CLSM, and phosphatidylserine exposure on cell walls distal to the infection site, as detected by Annexin V FLUOS-CLSM. These two responses may facilitate cell killing and enhance transportation of cell wall materials used for cell wall thickening, respectively. The cells beneath the necrotic tissue were enlarged and divided to form periclinal cell walls, resulting in extensive formation of several parallel boundary layers at the later stages of infection, accompanying the deposition of wall fortification materials for strengthening structural defenses. These results suggest that nonhost resistance of chili pepper fruit against the nonhost necrotrophic pathogen Xag 8ra is activated systematically from the initial infection until termination of the infection cycle, resulting in complete inhibition of bacterial pathogenesis by utilizing organ-specific in situ physiological events governed by the expression of genes in the plant fruit organ.

  2. Sequestered Alkaloid Defenses in the Dendrobatid Poison Frog Oophaga pumilio Provide Variable Protection from Microbial Pathogens.

    Science.gov (United States)

    Hovey, Kyle J; Seiter, Emily M; Johnson, Erin E; Saporito, Ralph A

    2018-03-01

    Most amphibians produce their own defensive chemicals; however, poison frogs sequester their alkaloid-based defenses from dietary arthropods. Alkaloids function as a defense against predators, and certain types appear to inhibit microbial growth. Alkaloid defenses vary considerably among populations of poison frogs, reflecting geographic differences in availability of dietary arthropods. Consequently, environmentally driven differences in frog defenses may have significant implications regarding their protection against pathogens. While natural alkaloid mixtures in dendrobatid poison frogs have recently been shown to inhibit growth of non-pathogenic microbes, no studies have examined the effectiveness of alkaloids against microbes that infect these frogs. Herein, we examined how alkaloid defenses in the dendrobatid poison frog, Oophaga pumilio, affect growth of the known anuran pathogens Aeromonas hydrophila and Klebsiella pneumoniae. Frogs were collected from five locations throughout Costa Rica that are known to vary in their alkaloid profiles. Alkaloids were isolated from individual skins, and extracts were assayed against both pathogens. Microbe subcultures were inoculated with extracted alkaloids to create dose-response curves. Subsequent spectrophotometry and cell counting assays were used to assess growth inhibition. GC-MS was used to characterize and quantify alkaloids in frog extracts, and our results suggest that variation in alkaloid defenses lead to differences in inhibition of these pathogens. The present study provides the first evidence that alkaloid variation in a dendrobatid poison frog is associated with differences in inhibition of anuran pathogens, and offers further support that alkaloid defenses in poison frogs confer protection against both pathogens and predators.

  3. 77 FR 12255 - Renewal of Department of Defense Federal Advisory Committees

    Science.gov (United States)

    2012-02-29

    ... recommendations for the continuous improvements of such policies and programs. The Task Force, pursuant to section...-medical case management; iv. The disability evaluation process for members of the Armed Forces; v... amending the charter for the Department of Defense Task Force on the Care, Management, and Transition of...

  4. 75 FR 32122 - Revisions to Defense Priorities and Allocations System Regulations

    Science.gov (United States)

    2010-06-07

    ... INFORMATION CONTACT: John Isbell, Director (Acting), Defense Programs Division, Office of Strategic Industries.... 700.15 would reflect the time period in which the Office of Strategic Industries and Economic Security... allocation action; (c) The written signature on a manually placed order, or the digital signature or name on...

  5. 76 FR 2151 - Assumption Buster Workshop: Defense-in-Depth is a Smart Investment for Cyber Security

    Science.gov (United States)

    2011-01-12

    ... day-long workshop on the pros and cons of the defense-in-depth strategy for cyber security. The... Technology Research and Development (NITRD) Program. ACTION: Call for participation. FOR FURTHER INFORMATION... Information Technology Research and Development (NITRD) Program on behalf of the SCORE Committee. Background...

  6. 75 FR 5288 - Strategic Environmental Research and Development Program, Scientific Advisory Board

    Science.gov (United States)

    2010-02-02

    ... DEPARTMENT OF DEFENSE Office of the Secretary Strategic Environmental Research and Development Program, Scientific Advisory Board AGENCY: Department of Defense (DOD). ACTION: Notice. SUMMARY: This... requesting Strategic Environmental Research and Development Program funds in excess of $1M. This meeting is...

  7. Defense Business Transformation

    Science.gov (United States)

    2009-12-01

    Defense Business Transformation by Jacques S. Gansler and William Lucyshyn The Center for Technology and National...REPORT TYPE 3. DATES COVERED 00-00-2009 to 00-00-2009 4. TITLE AND SUBTITLE Defense Business Transformation 5a. CONTRACT NUMBER 5b. GRANT NUMBER...vii Part One: DoD Business Transformation

  8. U.S. Department of Energy Space and Defense Power Systems Program Ten-Year Strategic Plan, Volume 1 and Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Dwight, Carla

    2013-06-01

    The Department of Energy's Space and Defense Power Systems program provides a unique capability for supplying power systems that function in remote or hostile environments. This capability has been functioning since the early 1960s and counts the National Aeronautics and Space Administration as one of its most prominent customers. This enabling technology has assisted the exploration of our solar system including the planets Jupiter, Saturn, Mars, Neptune, and soon Pluto. This capability is one-of-kind in the world in terms of its experience (over five decades), breadth of power systems flown (over two dozen to date) and range of power levels (watts to hundreds of watts). This document describes the various components of that infrastructure, work scope, funding needs, and its strategic plans going forward.

  9. Nuclear and Chemical Weapons and Materiel: Chemical Surety

    National Research Council Canada - National Science Library

    2001-01-01

    .... It has been revised to update responsibilities, Personnel Reliability Program (PRP) procedures, transportation policies, chemical event notification, chemical accident or incident response and assistance (CAIRA...

  10. 32 CFR 542.7 - Program information.

    Science.gov (United States)

    2010-07-01

    .... Also schools or students must provide uniforms, if desired, in the NDCC program. Schools desiring to... Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY MILITARY EDUCATION SCHOOLS AND COLLEGES... schools. The NDCC differs from the JROTC in that NDCC instructors must be provided by the school. Although...

  11. 76 FR 81918 - Strategic Environmental Research and Development Program (SERDP), Scientific Advisory Board...

    Science.gov (United States)

    2011-12-29

    ... DEPARTMENT OF DEFENSE Office of the Secretary Strategic Environmental Research and Development Program (SERDP), Scientific Advisory Board; Notice of Meeting AGENCY: Department of Defense. ACTION... research and development projects requesting Strategic Environmental Research and Development Program...

  12. Self-Defense in Karabakh Conflict?

    Directory of Open Access Journals (Sweden)

    Saeed Bagheri

    2015-01-01

    Full Text Available Use of force is one of the principles of international law that has been banned by the UN Charter and modern constitutions. However, since the enforcement of the UN Charter, self-defense has become the preferred excuse for states to justify their use of force. Applying self-defense, however, requires some conditions. Immediacy is one of the important conditions of self-defense. This is defined as the timeframe between armed attacks and reaction to it. This situation requires self-defense immediately after the armed conflict or during a reasonable timeframe since its occurance.In this respect, emerging Karabakh Conflict between Armenia and Azerbaijan in the 1990s is important. In this article, by comparing two different approaches (strict and board interpretation of the temporal link between the measures of self-defense and the armed attacks (immediacy, the temporal link between the self-defense countermeasures of Azerbaijan and attacks by Armenia in Karabakh Conflict will be examined.

  13. 32 CFR 199.20 - Continued Health Care Benefit Program (CHCBP).

    Science.gov (United States)

    2010-07-01

    ... Privilege Card”; (iii) A front and back copy of a DD Form 1173, “Uniformed Services Identification and...). 199.20 Section 199.20 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS CIVILIAN HEALTH AND MEDICAL PROGRAM OF THE UNIFORMED SERVICES (CHAMPUS...

  14. Organizing Defense Logistics: What Strategic Structures Should Exist for the Defense Supply Chain

    National Research Council Canada - National Science Library

    Maddox, Edward D

    2005-01-01

    .... The primary research question of this study was: What strategic organizational structures should exist within the Department of Defense to facilitate further integration of the defense supply chain...

  15. 75 FR 55778 - Strategic Environmental Research and Development Program, Scientific Advisory Board

    Science.gov (United States)

    2010-09-14

    ... DEPARTMENT OF DEFENSE Office of the Secretary Strategic Environmental Research and Development Program, Scientific Advisory Board AGENCY: Department of Defense. ACTION: Notice. SUMMARY: This notice is... requesting Strategic Environmental Research and Development Program funds in excess of $1M. This meeting is...

  16. Department of Defense Systems Engineering FY 2012 Annual Report

    Science.gov (United States)

    2013-03-01

    by the Utility Helicopter PMO, is utilizing the latest Defense Acquisition Guidelines and previously approved PEO AVN SEP examples to develop all...efforts. As a whole, all of PEO AVN Program Management Offices understand the importance of systems engineering. They stress the continued use of...established SE guidelines, practices and procedures throughout our acquisition processes. PEO AVN , working with the AMRDEC SE Division, has

  17. Defense Acquisitions: Department of Defense Actions on Program Manager Empowerment and Accountability

    National Research Council Canada - National Science Library

    2007-01-01

    .... In addition, as part of a new strategy for program manager empowerment and accountability, DOD plans a variety of actions to enhance development opportunities, provide more incentives, and arrange...

  18. The transuranic waste management program at Savannah River

    International Nuclear Information System (INIS)

    D'Ambrosia, J.

    1986-01-01

    Defense transuranic waste at the Savannah River site results from the Department of Energy's national defense activities, including the operation of production reactors, fuel reprocessing plants, and research and development activities. TRU waste has been retrievably stored at the Savannah River Plant since 1974 awaiting disposal. The Waste Isolation Pilot Plant, now under construction in New Mexico, is a research and development facility for demonstrating the safe disposal of defense TRU waste, including that in storage at the Savannah River Plant. The major objective of the TRU Program at SR is to support the TRU National Program, which is dedicated to preparing waste for, and emplacing waste in, the WIPP. Thus, the SR Program also supports WIPP operations. The SR site specific goals are to phase out the indefinite storage of TRU waste, which has been the mode of waste management since 1974, and to dispose of the defense TRU waste. This paper describes the specific activities at SR which will provide for the disposal of this TRU waste

  19. Redefining The U.S.-Japan Alliance: Tokyo’s National Defense Program

    Science.gov (United States)

    1994-11-01

    affairs to a member of the National Diet , a Fulbright Fellow at Tokyo University, a reporter for Defense News and the Iwate Nippo, and Tokyo...process of introducing electoral reform in the Diet has already split the LDP and led to the recent series of coalitions. The process of implementing this...what Malaysian Prime Minister Mahathir Mohamad told Japanese Prime Minister Murayama in August 1994. See "Mahathir to Japan: ’Drop War Apologies, Join

  20. 76 FR 46756 - Strategic Environmental Research and Development Program (SERDP), Scientific Advisory Board

    Science.gov (United States)

    2011-08-03

    ... DEPARTMENT OF DEFENSE Office of the Secretary Strategic Environmental Research and Development Program (SERDP), Scientific Advisory Board AGENCY: Department of Defense, Office of the Secretary. ACTION... Change program areas. These projects are requesting Strategic Environmental Research and Development...

  1. Chemical diversity in opisthobranch molluscs from scarcely investigated Indo-Pacific areas

    Digital Repository Service at National Institute of Oceanography (India)

    Wahidullah, S.; Guo, Y.-W.; Fakhr, I.M.I.; Mollo, E.

    on Nudibranchs Nudibranchs are exclusively carnivorous with a broad range of alimentary habits. They appear to have the ability to sequester, accumulate and modify dietary metabolites as well as to synthesize defensive compounds de novo (Cimino and Ghiselin... of the chemical data reviewed in this chapter, taking into account alimentary habits and geographical chemical variations, suggests some interesting generalizations. 8.6.1 Nudibranchs The intra-specific geographic variations observed in the chemical...

  2. A statistical analysis of individual success after successful completion of Defense Language Institute Foreign Language Center Training

    OpenAIRE

    Hinson, William B.

    2005-01-01

    "The Defense Language Institute Foreign Language Center (DLIFLC) trains students in various foreign languages and dialects for the Department of Defense (DOD). The majority of students are firstterm enlistees in the basic program. This study uses classification trees and logistic regression to understand the military, academic and personal characteristics that influence first-term success after successfully completing DLIFLC training. Success was defined as completing a firstterm enlistme...

  3. Chemical Dependency and Violence: Working with Dually Affected Families. A Cross-Training Program Manual for Counselors and Advocates.

    Science.gov (United States)

    Wright, Janet M.

    This manual is designed as a cross-training program guide for counselors working in the fields of woman abuse and chemical dependency. (A cross-training program is a system for one (or more) agency personnel to train each other in their respective areas of expertise.) Chapter 1 discusses the rationale and goals of a cross-training program; issues…

  4. Joint Logistics Commanders Guide for the Management of Multinational Program,

    Science.gov (United States)

    1981-07-01

    purchase of the A-300 Airbus and the 1977 record-breaking export performance of the French and UK aerospace industries of around $5 billion and $2 billion...DIS. They are the Defense Industrial Security Clearance Office ( DISCO ), the Defense Industrial Security Institute (DISI), and the Office of Industrial...Security International (ISI). Defense Industrial Security Clearance Office ( DISCO ) The Defense Industrial Security Program (DISP) establishes pro

  5. Development of Bi-phase sodium-oxygen-hydrogen chemical equilibrium calculation program (BISHOP) using Gibbs free energy minimization method

    International Nuclear Information System (INIS)

    Okano, Yasushi

    1999-08-01

    In order to analyze the reaction heat and compounds due to sodium combustion, the multiphase chemical equilibrium calculation program for chemical reaction among sodium, oxygen and hydrogen is developed in this study. The developed numerical program is named BISHOP; which denotes Bi-Phase, Sodium - Oxygen - Hydrogen, Chemical Equilibrium Calculation Program'. Gibbs free energy minimization method is used because of the special merits that easily add and change chemical species, and generally deal many thermochemical reaction systems in addition to constant temperature and pressure one. Three new methods are developed for solving multi-phase sodium reaction system in this study. One is to construct equation system by simplifying phase, and the other is to expand the Gibbs free energy minimization method into multi-phase system, and the last is to establish the effective searching method for the minimum value. Chemical compounds by the combustion of sodium in the air are calculated using BISHOP. The Calculated temperature and moisture conditions where sodium-oxide and hydroxide are formed qualitatively agree with the experiments. Deformation of sodium hydride is calculated by the program. The estimated result of the relationship between the deformation temperature and pressure closely agree with the well known experimental equation of Roy and Rodgers. It is concluded that BISHOP can be used for evaluated the combustion and deformation behaviors of sodium and its compounds. Hydrogen formation condition of the dump-tank room at the sodium leak event of FBR is quantitatively evaluated by BISHOP. It can be concluded that to keep the temperature of dump-tank room lower is effective method to suppress the formation of hydrogen. In case of choosing the lower inflammability limit of 4.1 mol% as the hydrogen concentration criterion, formation reaction of sodium hydride from sodium and hydrogen is facilitated below the room temperature of 800 K, and concentration of hydrogen

  6. Computer program to solve two-dimensional shock-wave interference problems with an equilibrium chemically reacting air model

    Science.gov (United States)

    Glass, Christopher E.

    1990-08-01

    The computer program EASI, an acronym for Equilibrium Air Shock Interference, was developed to calculate the inviscid flowfield, the maximum surface pressure, and the maximum heat flux produced by six shock wave interference patterns on a 2-D, cylindrical configuration. Thermodynamic properties of the inviscid flowfield are determined using either an 11-specie, 7-reaction equilibrium chemically reacting air model or a calorically perfect air model. The inviscid flowfield is solved using the integral form of the conservation equations. Surface heating calculations at the impingement point for the equilibrium chemically reacting air model use variable transport properties and specific heat. However, for the calorically perfect air model, heating rate calculations use a constant Prandtl number. Sample calculations of the six shock wave interference patterns, a listing of the computer program, and flowcharts of the programming logic are included.

  7. Immunity, suicide or both? Ecological determinants for the combined evolution of anti-pathogen defense systems.

    Science.gov (United States)

    Iranzo, Jaime; Lobkovsky, Alexander E; Wolf, Yuri I; Koonin, Eugene V

    2015-03-13

    Parasite-host arms race is one of the key factors in the evolution of life. Most cellular life forms, in particular prokaryotes, possess diverse forms of defense against pathogens including innate immunity, adaptive immunity and programmed cell death (altruistic suicide). Coevolution of these different but interacting defense strategies yields complex evolutionary regimes. We develop and extensively analyze a computational model of coevolution of different defense strategies to show that suicide as a defense mechanism can evolve only in structured populations and when the attainable degree of immunity against pathogens is limited. The general principle of defense evolution seems to be that hosts do not evolve two costly defense mechanisms when one is sufficient. Thus, the evolutionary interplay of innate immunity, adaptive immunity and suicide, leads to an equilibrium state where the combination of all three defense strategies is limited to a distinct, small region of the parameter space. The three strategies can stably coexist only if none of them are highly effective. Coupled adaptive immunity-suicide systems, the existence of which is implied by the colocalization of genes for the two types of defense in prokaryotic genomes, can evolve either when immunity-associated suicide is more efficacious than other suicide systems or when adaptive immunity functionally depends on the associated suicide system. Computational modeling reveals a broad range of outcomes of coevolution of anti-pathogen defense strategies depending on the relative efficacy of different mechanisms and population structure. Some of the predictions of the model appear compatible with recent experimental evolution results and call for additional experiments.

  8. 32 CFR 33.25 - Program income.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Program income. 33.25 Section 33.25 National... Post-Award Requirements Financial Administration § 33.25 Program income. (a) General. Grantees are encouraged to earn income to defray program costs. Program income includes income from fees for services...

  9. 76 FR 49753 - Strategic Environmental Research and Development Program Scientific Advisory Board Meeting

    Science.gov (United States)

    2011-08-11

    ... DEPARTMENT OF DEFENSE Office of the Secretary Strategic Environmental Research and Development Program Scientific Advisory Board Meeting AGENCY: Department of Defense. ACTION: Notice. SUMMARY: This... projects requesting Strategic Environmental Research and Development Program (SERDP) funds in excess of $1M...

  10. 48 CFR 212.7002 - Pilot program.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Pilot program. 212.7002... OF DEFENSE ACQUISITION PLANNING ACQUISITION OF COMMERCIAL ITEMS Pilot Program for Transition to Follow-On Contracting After Use of Other Transaction Authority 212.7002 Pilot program. ...

  11. Strategic Defense Initiative Overview

    National Research Council Canada - National Science Library

    1990-01-01

    ... to Third World and other nations. I will then discuss the scope of the SDI effort, the evolving strategic defense system architectures and theater defense, our compliancy with the ABM Treaty, technology spinoffs resulting from SDI...

  12. New generation of docking programs: Supercomputer validation of force fields and quantum-chemical methods for docking.

    Science.gov (United States)

    Sulimov, Alexey V; Kutov, Danil C; Katkova, Ekaterina V; Ilin, Ivan S; Sulimov, Vladimir B

    2017-11-01

    Discovery of new inhibitors of the protein associated with a given disease is the initial and most important stage of the whole process of the rational development of new pharmaceutical substances. New inhibitors block the active site of the target protein and the disease is cured. Computer-aided molecular modeling can considerably increase effectiveness of new inhibitors development. Reliable predictions of the target protein inhibition by a small molecule, ligand, is defined by the accuracy of docking programs. Such programs position a ligand in the target protein and estimate the protein-ligand binding energy. Positioning accuracy of modern docking programs is satisfactory. However, the accuracy of binding energy calculations is too low to predict good inhibitors. For effective application of docking programs to new inhibitors development the accuracy of binding energy calculations should be higher than 1kcal/mol. Reasons of limited accuracy of modern docking programs are discussed. One of the most important aspects limiting this accuracy is imperfection of protein-ligand energy calculations. Results of supercomputer validation of several force fields and quantum-chemical methods for docking are presented. The validation was performed by quasi-docking as follows. First, the low energy minima spectra of 16 protein-ligand complexes were found by exhaustive minima search in the MMFF94 force field. Second, energies of the lowest 8192 minima are recalculated with CHARMM force field and PM6-D3H4X and PM7 quantum-chemical methods for each complex. The analysis of minima energies reveals the docking positioning accuracies of the PM7 and PM6-D3H4X quantum-chemical methods and the CHARMM force field are close to one another and they are better than the positioning accuracy of the MMFF94 force field. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. MOQPSO-D/S for Air and Missile Defense WTA Problem under Uncertainty

    Directory of Open Access Journals (Sweden)

    Hao Xu

    2017-01-01

    Full Text Available Aiming at the shortcomings of single objective optimization for solving weapon target assignment (WTA and the existing multiobjective optimization based WTA method having problems being applied in air and missile defense combat under uncertainty, a fuzzy multiobjective programming based WTA method was proposed to enhance the adaptability of WTA decision to the changes of battlefield situation. Firstly, a multiobjective quantum-behaved particle swarm optimization with double/single-well (MOQPSO-D/S algorithm was proposed by adopting the double/single-well based position update method, the hybrid random mutation method, and the two-stage based guider particles selection method. Secondly, a fuzzy multiobjective programming WTA model was constructed with consideration of air and missile defense combat’s characteristics. And, the uncertain WTA model was equivalently clarified based on the necessity degree principle of uncertainty theory. Thirdly, with particles encoding and illegal particles adjusting, the MOQPSO-D/S algorithm was adopted to solve the fuzzy multiobjective programming based WTA model. Finally, example simulation was conducted, and the result shows that the WTA model constructed is rational and MOQPSO-D/S algorithm is efficient.

  14. Summary Report on the Audit of Defense Logistics Agency 1995 Defense Base Realignment and Closure Data Collection Process.

    Science.gov (United States)

    1995-06-19

    VXW-ÄVAVKVX’AWXW/XVXV:*: OFFICE OF THE INSPECTOR GENERAL SUMMARY REPORT ON THE AUDIT OF DEFENSE LOGISTICS AGENCY 1995 DEFENSE BASE REALIGNMENT...FOR DIRECTOR, DEFENSE LOGISTICS AGENCY SUBJECT: Summary Report on the Audit of Defense Logistics Agency 1995 Defense Base Realignment and Closure...the data that DLA provides to support recommendations for the 1995 Commission. The specific objective for the audits was to determine whether the

  15. Overview of DOE's Transuranic Waste Program

    International Nuclear Information System (INIS)

    McFadden, M.H.; Detamore, J.A.

    1987-01-01

    The US Department of Energy has assigned to Albuquerque Operations the Defense Transuranic Waste Program responsibility for long-range planning and management of defense transuranic (TRU) waste. The Transuranic Waste Lead Organization (TLO) has divided the Program into seven elements which support it's primary goal of ending interim storage and achieving permanent disposal. These are: waste generation site activities, storage site activities, burial site activities, technology development, transportation, institutional activities, and permanent disposal. This paper will briefly discuss these seven elements and how they are integrated to provide for successful achievement of the primary goal

  16. Annual Report of the Secretary of Defense to the President and the Congress, January 1994

    Science.gov (United States)

    1994-01-01

    Navy has assumed the lead on the ATARS program. The 1U-2 program was transferred back to DoD from the National Foreign Intelligence Program (NFIP...Activities - Civil Affairs ,Speciai Activities Psychological Operations -Coalition Suppor SOF’s Role in Support of D~efense Strategy SOF will...operations that misled the enemy about the coalition’s operational plan. According to information obtained from prisoners of war, psychological

  17. Evaluating Security Assistance Programs: Performance Evaluation and the Expanded International Military Education and Training (E-IMET) Program

    National Research Council Canada - National Science Library

    Calhoun, Todd

    1998-01-01

    In 1991 the International Military Education and Training (IMET) program was expanded to include training programs focusing on civilian control over the military, respect for human rights, and responsible defense resource management...

  18. 77 FR 49439 - Strategic Environmental Research and Development Program, Scientific Advisory Board; Notice of...

    Science.gov (United States)

    2012-08-16

    ... DEPARTMENT OF DEFENSE Office of the Secretary Strategic Environmental Research and Development Program, Scientific Advisory Board; Notice of Meeting AGENCY: Department of Defense. ACTION: Notice... research and development projects requesting Strategic Environmental Research and Development Program funds...

  19. 77 FR 26521 - Strategic Environmental Research and Development Program, Scientific Advisory Board; Notice of...

    Science.gov (United States)

    2012-05-04

    ... DEPARTMENT OF DEFENSE Office of the Secretary Strategic Environmental Research and Development Program, Scientific Advisory Board; Notice of Meeting AGENCY: Department of Defense. ACTION: Notice... development projects requesting Strategic Environmental Research and Development Program (SERDP) funds in...

  20. Using the Defensive Style Questionnaire to evaluate the impact of sex reassignment surgery on defensive mechanisms in transsexual patients Aplicação do Defensive Style Questionnaire para avaliar o impacto da cirurgia de redesignação sexual nos mecanismos de defesa de pacientes transexuais

    Directory of Open Access Journals (Sweden)

    Maria Inês Lobato

    2009-12-01

    Full Text Available Objective: To evaluate the impact of sex reassignment surgery on the defense mechanisms of 32 transsexual patients at two different points in time using the Defensive Style Questionnaire. Method: The Defensive Style Questionnaire was applied to 32 patients upon their admission to the Gender Identity Disorder Program, and 12 months after they had undergone sex reassignment surgery. Results: There were changes in two defense mechanisms: anticipation and idealization. However, no significant differences were observed in terms of the mature, neurotic and immature categories. Discussion: One possible explanation for this result is the fact that the procedure does not resolve gender dysphoria, which is a core symptom in such patients. Another aspect is related to the early onset of the gender identity disorder, which determines a more regressive defensive structure in these patients. Conclusion: Sex reassignment surgery did not improve the defensive profile as measured by the Defensive Style Questionnaire.Objetivo: Avaliar o efeito da cirurgia de redesignação sexual nos mecanismos de defesa de 32 pacientes transexuais em dois momentos do estudo usando o Defensive Style Questionnaire. Método: O Defensive Style Questionnaire foi aplicado a 32 pacientes quando ingressaram no Programa de Transtorno de Identidade de Gênero e 12 meses após a cirurgia de redesignação sexual. Resultados: Houve modificações em dois mecanismos de defesa: antecipação e idealização; porém, sem mudanças significativas nos fatores maduro, neurótico e imaturo. Discussão: Uma possibilidade para esse resultado é o fato de a intervenção cirúrgica não resolver a disforia de gênero (principal sintoma desses pacientes. Outro aspecto está relacionado com o fato de o transtorno de identidade de gênero ser instalado precocemente, o que determina uma estrutura defensiva mais regressiva para esses pacientes. Conclusão: A cirurgia de redesignação sexual não foi