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Sample records for characterization case study

  1. Systematic analytical characterization of new psychoactive substances: A case study.

    Science.gov (United States)

    Lobo Vicente, Joana; Chassaigne, Hubert; Holland, Margaret V; Reniero, Fabiano; Kolář, Kamil; Tirendi, Salvatore; Vandecasteele, Ine; Vinckier, Inge; Guillou, Claude

    2016-08-01

    New psychoactive substances (NPS) are synthesized compounds that are not usually covered by European and/or international laws. With a slight alteration in the chemical structure of existing illegal substances registered in the European Union (EU), these NPS circumvent existing controls and are thus referred to as "legal highs". They are becoming increasingly available and can easily be purchased through both the internet and other means (smart shops). Thus, it is essential that the identification of NPS keeps up with this rapidly evolving market. In this case study, the Belgian Customs authorities apprehended a parcel, originating from China, containing two samples, declared as being "white pigments". For routine identification, the Belgian Customs Laboratory first analysed both samples by gas-chromatography mass-spectrometry and Fourier-Transform Infrared spectroscopy. The information obtained by these techniques is essential and can give an indication of the chemical structure of an unknown substance but not the complete identification of its structure. To bridge this gap, scientific and technical support is ensured by the Joint Research Centre (JRC) to the European Commission Directorate General for Taxation and Customs Unions (DG TAXUD) and the Customs Laboratory European Network (CLEN) through an Administrative Arrangement for fast recognition of NPS and identification of unknown chemicals. The samples were sent to the JRC for a complete characterization using advanced techniques and chemoinformatic tools. The aim of this study was also to encourage the development of a science-based policy driven approach on NPS. These samples were fully characterized and identified as 5F-AMB and PX-3 using (1)H and (13)C nuclear magnetic resonance (NMR), high-resolution tandem mass-spectrometry (HR-MS/MS) and Raman spectroscopy. A chemoinformatic platform was used to manage, unify analytical data from multiple techniques and instruments, and combine it with chemical and

  2. Characterizing snowmelt regime of the river swat - a case study

    International Nuclear Information System (INIS)

    Malik, M.A.

    2015-01-01

    Snowmelt generates 70 to 80% of runoff of Indus River and its tributaries. Forecasting snowmelt generated flow is important for water management, reservoir operation and channel diversion. River Swat being not direct contributor to the existing reservoirs remained out of focus for characterizing its snowmelt regime. Thirty years (1971-2000) data of upper Swat catchment above Kalam gauging station was acquired from WAPDA. Normal monthly values over the period and average monthly values of each year were determined for stream flow, precipitation and temperature together with average monthly values of weighted and maximum temperature. Snowmelt regime was ascertained from plot of normal values of flow, precipitation and temperature. Using temperature index approach, average monthly flow over the snowmelt months (April, May and June) in terms of mm depth over the catchment was regressed on all the temperature indices using exponential, power and third degree polynomial functions. Tmax was found the best index for snowmelt with R2 as 0.902 for the third degree polynomial function. Runoff coefficient (ROC) for the total precipitation was conceptualized and through iteration was found as T max 100. The optimized value of ROC was used to segregate rain induced and snowmelt induced runoff. The segregated snowmelt induced runoff was again regressed on Tmax using the same function which slightly improved R2 to 0.916. The model was tested for four years of data and forecasted flow was found reasonable in the context of simplicity of the approach. (author)

  3. Remote Characterization of Biomass Measurements: Case Study of Mangrove Forests

    Science.gov (United States)

    Fatoyinbo, Temilola E.

    2010-01-01

    Accurately quantifying forest biomass is of crucial importance for climate change studies. By quantifying the amount of above and below ground biomass and consequently carbon stored in forest ecosystems, we are able to derive estimates of carbon sequestration, emission and storage and help close the carbon budget. Mangrove forests, in addition to providing habitat and nursery grounds for over 1300 animal species, are also an important sink of biomass. Although they only constitute about 3% of the total forested area globally, their carbon storage capacity -- in forested biomass and soil carbon -- is greater than that of tropical forests (Lucas et al, 2007). In addition, the amount of mangrove carbon -- in the form of litter and leaves exported into offshore areas is immense, resulting in over 10% of the ocean's dissolved organic carbon originating from mangroves (Dittmar et al, 2006) The measurement of forest above ground biomass is carried out on two major scales: on the plot scale, biomass can be measured using field measurements through allometric equation derivation and measurements of forest plots. On the larger scale, the field data are used to calibrate remotely sensed data to obtain stand-wide or even regional estimates of biomass. Currently, biomass can be calculated using average stand biomass values and optical data, such as aerial photography or satellite images (Landsat, Modis, Ikonos, SPOT, etc.). More recent studies have concentrated on deriving forest biomass values using radar (JERS, SIR-C, SRTM, Airsar) and/or lidar (ICEsat/GLAS, LVIS) active remote sensing to retrieve more accurate and detailed measurements of forest biomass. The implementation of a generation of new active sensors (UAVSar, DesdynI, Alos/Palsar, TerraX) has prompted the development of new tecm'liques of biomass estimation that use the combination of multiple sensors and datasets, to quantify past, current and future biomass stocks. Focusing on mangrove forest biomass estimation

  4. Characterization of the elastic displacement demand: Case study - Sofia city

    International Nuclear Information System (INIS)

    Paskaleva, I.; Kouteva, M.; Vaccari, F.; Panza, G.F.

    2008-02-01

    The results of the study on the seismic site response in a part of the metropolitan Sofia are discussed. The neo-deterministic seismic hazard assessment procedure has been used to compute realistic synthetic waveforms considering four earthquake scenarios, with magnitudes M = 3.7, M = 6.3 and M = 7.0. Source and site specific ground motion time histories are computed along three investigated cross sections, making use of the hybrid approach, combining the modal summation technique and the finite differences scheme. Displacement and acceleration response spectra are considered. These results are validated against the design elastic displacement response spectra and displacement demand, recommended in Eurocode 8. The elastic response design spectrum from the standard pseudo-acceleration, versus natural period, Tn, format is converted to the Sa - Sd format. The elastic displacement response spectra and displacement demand are discussed with respect to the earthquake magnitude, the seismic source-to-site distance, seismic source mechanism, and the local geological site conditions. (author)

  5. Atomic Force Microscopy Techniques for Nanomechanical Characterization: A Polymeric Case Study

    Science.gov (United States)

    Reggente, Melania; Rossi, Marco; Angeloni, Livia; Tamburri, Emanuela; Lucci, Massimiliano; Davoli, Ivan; Terranova, Maria Letizia; Passeri, Daniele

    2015-04-01

    Atomic force microscopy (AFM) is a versatile tool to perform mechanical characterization of surface samples at the nanoscale. In this work, we review two of such methods, namely contact resonance AFM (CR-AFM) and torsional harmonics AFM (TH-AFM). First, such techniques are illustrated and their applicability on materials with elastic moduli in different ranges are discussed, together with their main advantages and limitations. Then, a case study is presented in which we report the mechanical characterization using both CR-AFM and TH-AFM of polyaniline and polyaniniline doped with nanodiamond particles tablets prepared by a pressing process. We determined the indentation modulus values of their surfaces, which were found in fairly good agreement, thus demonstrating the accuracy of the techniques. Finally, the determined surface elastic moduli have been compared with the bulk ones measured through standard indentation testing.

  6. Characterizing and controlling industrial dust: a case study in small particle measurement.

    Science.gov (United States)

    Combes, Richard S; Warren, D Alan

    2005-07-01

    Instrumentation used to measure characteristics of fine particles entrained in gas or suspended in aerosols provides information needed to develop valid regulations for emission sources and to support the design of control technologies. This case study offers a brief history of "micromeritics," a term used by early researchers to describe the science of small particles, and the related invention of laboratory instruments for characterizing very fine particles. The historical view provides insights into the role that Progressive Era government agencies played in advancing esoteric science and applying this knowledge to the regulation of workplace air pollution. Micromeritics instrumentation developed in conjunction with federal research now has many commercial applications worldwide, with characterizing airborne pollutants only a minor one. However, the continuing advances in the micromeritics field provide important laboratory measurement capabilities to environmental research organizations, such as the National Institute for Occupational Safety and Health (NIOSH).

  7. Qualitative Task Analysis to Enhance Sports Characterization: A Surfing Case Study

    Directory of Open Access Journals (Sweden)

    Moreira Miguel

    2014-10-01

    Full Text Available The aim of this study was to develop a Matrix of Analysis for Sports Tasks (MAST, regardless of the sports activity, based on practice classification and task analysis. Being this a qualitative research our main question was: in assessing sports’ structure is it possible to make the characterization of any discipline through context and individuals’ behaviours? The sample was within a surf discipline in a competition flowing having 5 of the top 16 Portuguese surfers training together. Based on a qualitative method, studying the surf as the main activity was an interpretative study case. The MAST was applied in four phases: taxonomy; tasks and context description; task analysis; teaching and performance strategies. Its application allowed the activities’ characterization through the observation, surfer’s opinions and bibliographical support. The triangulation of the data was used as an information data treatment. The elements were classified by the challenges proposed to the practitioners and the taxonomy was constituted by the sport activities, group, modality and discipline. Surf is a discipline of surfing which is a sliding sport modality, therefore, a nature sport. In the context description, we had the wave’s components and constraints and the surfboards’ qualities. Through task analysis we obtained a taxonomy of surf manoeuvres. The structural and functional analysis allowed finding solutions for learning of surf techniques with trampoline and skateboards because these fit in sliding sports. MAST makes possible the development of strategies that benefit teaching and performance intervention

  8. Qualitative Task Analysis to Enhance Sports Characterization: A Surfing Case Study

    Science.gov (United States)

    Moreira, Miguel; Peixoto, César

    2014-01-01

    The aim of this study was to develop a Matrix of Analysis for Sports Tasks (MAST), regardless of the sports activity, based on practice classification and task analysis. Being this a qualitative research our main question was: in assessing sports’ structure is it possible to make the characterization of any discipline through context and individuals’ behaviours? The sample was within a surf discipline in a competition flowing having 5 of the top 16 Portuguese surfers training together. Based on a qualitative method, studying the surf as the main activity was an interpretative study case. The MAST was applied in four phases: taxonomy; tasks and context description; task analysis; teaching and performance strategies. Its application allowed the activities’ characterization through the observation, surfer’s opinions and bibliographical support. The triangulation of the data was used as an information data treatment. The elements were classified by the challenges proposed to the practitioners and the taxonomy was constituted by the sport activities, group, modality and discipline. Surf is a discipline of surfing which is a sliding sport modality, therefore, a nature sport. In the context description, we had the wave’s components and constraints and the surfboards’ qualities. Through task analysis we obtained a taxonomy of surf manoeuvres. The structural and functional analysis allowed finding solutions for learning of surf techniques with trampoline and skateboards because these fit in sliding sports. MAST makes possible the development of strategies that benefit teaching and performance intervention. PMID:25414757

  9. A Case Study of German Language Core Journals for Characterizing Citation Patterns in the Social Sciences

    Directory of Open Access Journals (Sweden)

    Pei-Shan Chi

    2013-12-01

    Full Text Available Publication practices in the social sciences are characterized by the use of heterogeneous publication channels and a stronger national focus (Nederhof, 2006; Hicks & Wang, 2011. At the same time the use of bibliometric indicators in research evaluation promotes journal articles in international peer reviewed journals as the main style of publishing research results. The question emerges to which extent this changes publication practices in these disciplines. In our contribution we address this question and present results of a case study which investigates publication and referencing patterns of core German language journals in sociology and political science. Based on an explorative analysis of reference lists we describe patterns and changes of the parameters of the knowledge base of these journals. The analysis of the results in this study shows that with a total of 67% in the sociology and 76% in the political science the core German journals predominantly refer to non-journal publications. Besides, the share of non-source publications basically remains constant in the time period 2000-2009, and the share of references to source journals is the same in both disciplines. The difference between sociology and political science is: publications in the German language sociology journals have more references to monographs (46% than publications in the German language political science journals (38%, but these political science journals reference to other non-source publications (38% much more than sociology (21%.

  10. Characterizing New Channels of Communication: A Case Study of Municipal 311 Requests in Edmonton, Canada

    Directory of Open Access Journals (Sweden)

    Qing Lu

    2016-06-01

    Full Text Available City governments around the world are developing and expanding how they connect to citizens. Technologies play an important role in making this connection, and one frequent way that cities connect with citizens is through 311-style request systems. 311 is a non-emergency municipal notification system that uses telephone, email, web forms, and increasingly, mobile applications to allow citizens to notify government of infrastructure issues and make requests for municipal services. In many ways, this process of citizen contribution mirrors the provision of volunteered geographic information, that is spatially-referenced user generated content. This research presents a case study of the city of Edmonton, Canada, an early adopter of multi-channel 311 service request systems, including telephone, email, web form, and mobile app 311 request channels. Three methods of analysis are used to characterize and compare these different channels over three years of request data; a comparison of relative request share for each channel, a spatial hot spot analysis, and regression models to compare channel usage with sociodemographic variables. The results of this study indicate a shift in channel usage from traditional to Internet-enabled, that this shift is mirrored in the hotspots of request activity, and that specific digital inequalities exist that reinforce this distinction between traditional and Internet-enabled reporting channels.

  11. Generation and collection of restaurant waste: Characterization and evaluation at a case study in Italy.

    Science.gov (United States)

    Tatàno, Fabio; Caramiello, Cristina; Paolini, Tonino; Tripolone, Luca

    2017-03-01

    Because restaurants (as a division of the hospitality sector) contribute to the generation of commercial and institutional waste, thus representing both a challenge and an opportunity, the objective of the present study was to deepen the knowledge of restaurant waste in terms of the qualitative and quantitative characteristics of waste generation and the performance achievable by the implementation of a separate collection scheme. In this study, the generated waste was characterized and the implemented separate collection was evaluated at a relevant case study restaurant in a coastal tourist area of Central Italy (Marche Region, Adriatic Sea side). The qualitative (compositional) characterization of the generated total restaurant waste showed considerable incidences of, in decreasing order, food (28.2%), glass (22.6%), paper/cardboard (19.1%), and plastic (17.1%). The quantitative (parametric) characterization of the generated restaurant waste determined the unit generation values of total waste and individual fractions based on the traditional employee and area parameters and the peculiar meal parameter. In particular, the obtained representative values per meal were: 0.72kgmeal -1 for total waste, and ranging, for individual fractions, from 0.20 (for food) to 0.008kgmeal -1 (for textile). Based on the critical evaluation of some of the resulting unit waste generation values, possible influences of restaurant practices, conditions, or characteristics were pointed out. In particular, food waste generation per meal can likely be limited by: promoting and using local, fresh, and quality food; standardizing and limiting daily menu items; basing food recipes on consolidated cooking knowledge and experience; and limiting plate sizes. The evaluation of the monthly variation of the monitored separate collection, ranging from an higher level of 52.7% to a lower level of 41.4%, indicated the following: a reduction in the separate collection level can be expected at times of

  12. Case Studies on Facility Characterization with X-Ray Fluorescence Spectrometry

    International Nuclear Information System (INIS)

    Kirk, K.T.; Brooksbank, R.D.; Meszaros, J.M.; Towery, W.E.

    2008-01-01

    A hand-held x-ray fluorescence (XRF) analyzer is being used to characterize facilities in support of demolition activities at the East Tennessee Technology Park (ETTP) in Oak Ridge, Tennessee. Approximately 500 facilities at the U.S. Department of Energy site are being demolished under the ETTP Decontamination and Decommissioning (D and D) project. Facility characterization is being conducted to provide data for waste profiling and identify hazards to demolition workers. XRF spectrometry is a non-destructive analytical technique used to identify and quantify the elemental composition of a substance based on the intensity of its characteristic X-ray emission wavelength or energy. The Innov-X Systems R Model XT-245S XRF analyzer used at ETTP is equipped with a silver anode x-ray tube and a Si PIN diode detector. X-rays are generated by electrical current, eliminating the need for radioactive isotopes. Electronic components can be powered by either a lithium-ion battery or an A/C adapter, and the instrument is controlled by an iPAQ R pocket personal computer. The unit has two primary operating modes. Alloy analysis mode measures percent levels of elements in metals such as a pipes, valves, equipment, or construction materials. Soil mode provides parts-per-million (ppm) quantities in bulk solids like concrete dust, residue, paint chips, or soil. The hand-held unit can analyze material in place, or it can analyze samples in a test stand by remote operation. This paper present some case studies demonstrating a variety of XRF applications for facility characterization: Metal Materials Characterization, Lead Paint Identification, Hot Spot Delineation, Bulk Solids Testing. XRF has been the analytical technique of choice for identifying metal alloy components and has also been useful in analyzing bulk materials. Limitations of XRF testing include the inability to directly analyze elements with low atomic weights. Light elements such as beryllium and aluminum do not emit

  13. Functional characterization of muscle fibres from patients with chronic fatigue syndrome: case-control study.

    Science.gov (United States)

    Pietrangelo, T; Toniolo, L; Paoli, A; Fulle, S; Puglielli, C; Fanò, G; Reggiani, C

    2009-01-01

    Chronic fatigue syndrome (CFS) is a disabling condition characterized by unexplained chronic fatigue that impairs normal activities. Although immunological and psychological aspects are present, symptoms related to skeletal muscles, such as muscle soreness, fatigability and increased lactate accumulation, are prominent in CFS patients. In this case-control study, the phenotype of the same biopsy samples was analyzed by determining i) fibre-type proportion using myosin isoforms as fibre type molecular marker and gel electrophoresis as a tool to separate and quantify myosin isoforms, and ii) contractile properties of manually dissected, chemically made permeable and calcium-activated single muscle fibres. The results showed that fibre-type proportion was significantly altered in CSF samples, which showed a shift from the slow- to the fast-twitch phenotype. Cross sectional area, force, maximum shortening velocity and calcium sensitivity were not significantly changed in single muscle fibres from CSF samples. Thus, the contractile properties of muscle fibres were preserved but their proportion was changed, with an increase in the more fatigue-prone, energetically expensive fast fibre type. Taken together, these results support the view that muscle tissue is directly involved in the pathogenesis of CSF and it might contribute to the early onset of fatigue typical of the skeletal muscles of CFS patients.

  14. The use of gravity methods in the internal characterization of landfills—a case study

    International Nuclear Information System (INIS)

    Mantlík, František; Matias, Manuel; Grangeia, Carlos; Tareco, Hélder; Lourenço, Jose

    2009-01-01

    Some examples of the use of gravity exploration methods in landfills were published recently. However, density contrast between the landfill and the host media as well as the cost involved may be limiting factors to the application of gravimetry to this problem. Herein a case study of the application of gravity methods to the internal characterization of a sealed landfill is presented. This landfill is installed in recent low-density quaternary sand formations. Two north–south gravity profiles were carried out. The first profile crossed the landfill at its centre, whilst a second profile was done some distance away from the landfill to provide general regional information. The first profile was modelled in order to obtain lateral variations of density within the landfill that might be caused by different types of waste and/or the age of the waste deposits. Gravity modelling and interpretation were supported with data from resistivity profiles carried out in the immediate vicinity of the gravity measurements, i.e. the resistivity profiles interpretation results constrained the thickness of landfill deposits

  15. Municipal Solid Waste Characterization according to Different Income Levels: A Case Study

    Directory of Open Access Journals (Sweden)

    Huseyin Kurtulus Ozcan

    2016-10-01

    Full Text Available Solid waste generation and characterization are some of the most important parameters which affect environmental sustainability. Municipal solid waste (MSW characterization depends on social structure and income levels. This study aims to determine the variations in waste components within MSW mass by income levels and seasonal conditions following the analysis conducted on the characterization of solid wastes produced in the Kartal district of the province of Istanbul, which is the research area of this study. To this end, 1.9 tons of solid waste samples were collected to represent four different lifestyles (high, medium, and low income levels, and downtown in the winter and summer periods, and characterization was made on these samples. In order to support waste characterization, humidity content and calorific value analyses were also conducted and various suggestions were brought towards waste management in line with the obtained findings. According to the results obtained in the study, organic waste had the highest rate of waste mass by 57.69%. Additionally, significant differences were found in municipal solid waste components (MSWC based on income level. Average moisture content (MC of solid waste samples was 71.1% in moisture analyses. The average of calorific (heating value (HHV was calculated as 2518.5 kcal·kg−1.

  16. Diffuse Optical Characterization of the Healthy Human Thyroid Tissue and Two Pathological Case Studies.

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    Claus Lindner

    Full Text Available The in vivo optical and hemodynamic properties of the healthy (n = 22 and pathological (n = 2 human thyroid tissue were measured non-invasively using a custom time-resolved spectroscopy (TRS and diffuse correlation spectroscopy (DCS system. Medical ultrasound was used to guide the placement of the hand-held hybrid optical probe. TRS measured the absorption and reduced scattering coefficients (μa, μs' at three wavelengths (690, 785 and 830 nm to derive total hemoglobin concentration (THC and oxygen saturation (StO2. DCS measured the microvascular blood flow index (BFI. Their dependencies on physiological and clinical parameters and positions along the thyroid were investigated and compared to the surrounding sternocleidomastoid muscle. The THC in the thyroid ranged from 131.9 μM to 144.8 μM, showing a 25-44% increase compared to the surrounding sternocleidomastoid muscle tissue. The blood flow was significantly higher in the thyroid (BFIthyroid = 16.0 × 10-9 cm2/s compared to the muscle (BFImuscle = 7.8 × 10-9 cm2/s, while StO2 showed a small (StO2, muscle = 63.8% to StO2, thyroid = 68.4%, yet significant difference. Two case studies with thyroid nodules underwent the same measurement protocol prior to thyroidectomy. Their THC and BFI reached values around 226.5 μM and 62.8 × 10-9 cm2/s respectively showing a clear contrast to the nodule-free thyroid tissue as well as the general population. The initial characterization of the healthy and pathologic human thyroid tissue lays the ground work for the future investigation on the use of diffuse optics in thyroid cancer screening.

  17. Applied dendroecology and environmental forensics. Characterizing and age dating environmental releases: fundamentals and case studies

    Science.gov (United States)

    Jean-Christophe Balouet; Gil Oudijk; Kevin T. Smith; Ioana Petrisor; Hakan Grudd; Bengt. Stocklassa

    2007-01-01

    Dendroecology, or the use of ring patterns to assess the age of trees and environmental factors controlling their growth, is a well-developed method in climatologic studies. This method holds great potential as a forensic tool for age dating, contamination assessment, and characterization of releases. Moreover, the method is independent of the physical presence of...

  18. Detailed site characterization for final disposal of spent fuel in Finland - Case study Loviisa

    International Nuclear Information System (INIS)

    Anttila, P.; Ahokas, H.; Ruotsalainen, P.; Cosma, C.; Keskinen, J.; Hinkkanen, H.; Rouhiainen, P.; Oehberg, A.

    1998-01-01

    The spent fuel from the Finnish nuclear power plants will be disposed of in the Finnish bedrock. Pos iva Oy is responsible for the site selection programme carried out in accordance with the governmental decisions. Preliminary site investigations were made in five areas in 1987-1992. Based on the results, three areas, Romuvaara in Kuhmo, Kivetty in Aeaenekoski and Olkiluoto in Eurajoki, were selected for the detailed site characterization in 1993-2000. The final site will be selected by the end of the year 2000. The interim reporting of the detailed studies of the three areas was made in 1996. In 1997, the island of Haestholmen, as the host to the Loviisa NPP, was included as a fourth candidate site in the programme for the detailed site investigations. The goal is to characterize this site also in detail by the end of 2000 to attain the same level of knowledge as available from the three other sites. The background information existing from the studies made for the construction of the repository for the low-and intermediate-level wastes will create a good basis to reach the target. The research programme for the detailed site characterization has mainly been focused on groundwater flow and geochemistry due to their importance in terms of long-term safety of the repository. Equipment and methodology development by Posiva has introduced new tools that provide more accurate data on relevant parameters than the ones used in previous stages of site characterization. The programme also contains studies for additional information of the structural and geological properties of the bedrock towards the depth. Also predictive modelling has been made for evaluating the relevance of the assumptions made. The methods applied in the site characterization have comprised, e.g., geological mapping, deep core drilling, groundwater sampling and analyzing, hydraulic testing and geophysical measurements

  19. Detailed site characterization for final disposal of spent fuel in Finland - Case study Loviisa

    Energy Technology Data Exchange (ETDEWEB)

    Anttila, P. [IVO Power Engineering Ltd. (Finland); Ahokas, H.; Ruotsalainen, P. [Fintact Oy (Finland); Cosma, C.; Keskinen, J. [Vibrometric Oy (Finland); Hinkkanen, H. [Posiva Oy (Finland); Rouhiainen, P. [PRG-Tec Oy (Finland); Oehberg, A. [Saanio and Riekkola Consulting Engineers (Finland)

    1998-09-01

    The spent fuel from the Finnish nuclear power plants will be disposed of in the Finnish bedrock. Pos iva Oy is responsible for the site selection programme carried out in accordance with the governmental decisions. Preliminary site investigations were made in five areas in 1987-1992. Based on the results, three areas, Romuvaara in Kuhmo, Kivetty in Aeaenekoski and Olkiluoto in Eurajoki, were selected for the detailed site characterization in 1993-2000. The final site will be selected by the end of the year 2000. The interim reporting of the detailed studies of the three areas was made in 1996. In 1997, the island of Haestholmen, as the host to the Loviisa NPP, was included as a fourth candidate site in the programme for the detailed site investigations. The goal is to characterize this site also in detail by the end of 2000 to attain the same level of knowledge as available from the three other sites. The background information existing from the studies made for the construction of the repository for the low-and intermediate-level wastes will create a good basis to reach the target. The research programme for the detailed site characterization has mainly been focused on groundwater flow and geochemistry due to their importance in terms of long-term safety of the repository. Equipment and methodology development by Posiva has introduced new tools that provide more accurate data on relevant parameters than the ones used in previous stages of site characterization. The programme also contains studies for additional information of the structural and geological properties of the bedrock towards the depth. Also predictive modelling has been made for evaluating the relevance of the assumptions made. The methods applied in the site characterization have comprised, e.g., geological mapping, deep core drilling, groundwater sampling and analyzing, hydraulic testing and geophysical measurements 23 refs, 4 figs

  20. A multi-method approach toward de novo glycan characterization: a Man-5 case study.

    Science.gov (United States)

    Prien, Justin M; Prater, Bradley D; Cockrill, Steven L

    2010-05-01

    Regulatory agencies' expectations for biotherapeutic approval are becoming more stringent with regard to product characterization, where minor species as low as 0.1% of a given profile are typically identified. The mission of this manuscript is to demonstrate a multi-method approach toward de novo glycan characterization and quantitation, including minor species at or approaching the 0.1% benchmark. Recently, unexpected isomers of the Man(5)GlcNAc(2) (M(5)) were reported (Prien JM, Ashline DJ, Lapadula AJ, Zhang H, Reinhold VN. 2009. The high mannose glycans from bovine ribonuclease B isomer characterization by ion trap mass spectrometry (MS). J Am Soc Mass Spectrom. 20:539-556). In the current study, quantitative analysis of these isomers found in commercial M(5) standard demonstrated that they are in low abundance (2-aminobenzoic acid to detect and chromatographically resolve multiple M(5) isomers in bovine ribonuclease B. With this multi-method approach, we have the capabilities to comprehensively characterize a biotherapeutic's glycan array in a de novo manner, including structural isomers at >/=0.1% of the total chromatographic peak area.

  1. Methodology for characterizing the environmental impacts of hydroelectric generating stations : a case study of Farmer Rapids

    International Nuclear Information System (INIS)

    Lemieux, C.; Renaud, S.; Begin, P.; Belzile, L.; Caumartin, J.

    2006-01-01

    This paper described a novel methodology used to characterize the downstream section of a generating station that was not navigable by boat. The method was used as part of a fish habitat characterization study conducted in the Farmers Rapids area of Quebec. The purpose of the study was to identify the discharges and water levels needed to preserve fish habitats in the region. Initially, experimental fishing was undertaken to locate, validate and characterize fish habitats. Habitat models were then developed using a microhabitat modelling method to establish pertinent discharges and water levels. In order to model areas that were not navigable by boat, discharges released by the generating station were reduced to a minimum to temporarily decrease water levels and expose the river. High definition aerial photography and topographic mapping was conducted. The information obtained from the 2 procedures was then used to describe and map the riverbed substrate as well as the bathymetry and aquatic habitats. A 2D hydrodynamic model was then used to simulate water flows in the area at various discharges. The results of the hydrodynamic models and the habitat models were then used to establish appropriate discharges for optimal fish habitats

  2. Basalt characterization by means of nuclear and electrical well logging techniques. Case study from Southern Syria

    International Nuclear Information System (INIS)

    Asfahani, Jamal

    2011-01-01

    Nuclear well logging, including natural gamma ray, density, and neutron-porosity techniques are used with electrical well logging of long and short normal techniques to characterize the basaltic areas largely extended in Southern Syria. Statistical analysis approach with the threshold concept has been adapted for such characterization, where four kinds of basalt have been identified: very hard basalt, hard basalt, fractured basalt, and basalt alteration products. The spectrometric gamma technique has also been applied on the retrieved rock samples in order to determine the radioactive content (eU, eTh, and K%) of the basaltic section in the study area. No radioactive anomalies have been detected, the radioactive values are normal and in the expected range.

  3. Characterizing complexity in socio-technical systems: a case study of a SAMU Medical Regulation Center.

    Science.gov (United States)

    Righi, Angela Weber; Wachs, Priscila; Saurin, Tarcísio Abreu

    2012-01-01

    Complexity theory has been adopted by a number of studies as a benchmark to investigate the performance of socio-technical systems, especially those that are characterized by relevant cognitive work. However, there is little guidance on how to assess, systematically, the extent to which a system is complex. The main objective of this study is to carry out a systematic analysis of a SAMU (Mobile Emergency Medical Service) Medical Regulation Center in Brazil, based on the core characteristics of complex systems presented by previous studies. The assessment was based on direct observations and nine interviews: three of them with regulator of emergencies medical doctor, three with radio operators and three with telephone attendants. The results indicated that, to a great extent, the core characteristics of complexity are magnified) due to basic shortcomings in the design of the work system. Thus, some recommendations are put forward with a view to reducing unnecessary complexity that hinders the performance of the socio-technical system.

  4. Flow Regime Classification and Hydrological Characterization: A Case Study of Ethiopian Rivers

    Directory of Open Access Journals (Sweden)

    Belete Berhanu

    2015-06-01

    Full Text Available The spatiotemporal variability of a stream flow due to the complex interaction of catchment attributes and rainfall induce complexity in hydrology. Researchers have been trying to address this complexity with a number of approaches; river flow regime is one of them. The flow regime can be quantified by means of hydrological indices characterizing five components: magnitude, frequency, duration, timing, and rate of change of flow. Similarly, this study aimed to understand the flow variability of Ethiopian Rivers using the observed daily flow data from 208 gauging stations in the country. With this process, the Hierarchical Ward Clustering method was implemented to group the streams into three flow regimes (1 ephemeral, (2 intermittent, and (3 perennial. Principal component analysis (PCA is also applied as the second multivariate analysis tool to identify dominant hydrological indices that cause the variability in the streams. The mean flow per unit catchment area (QmAR and Base flow index (BFI show an incremental trend with ephemeral, intermittent and perennial streams. Whereas the number of mean zero flow days ratio (ZFI and coefficient of variation (CV show a decreasing trend with ephemeral to perennial flow regimes. Finally, the streams in the three flow regimes were characterized with the mean and standard deviation of the hydrological variables and the shape, slope, and scale of the flow duration curve. Results of this study are the basis for further understanding of the ecohydrological processes of the river basins in Ethiopia.

  5. Characterization of the polysensitized patient: a matched case-control study

    DEFF Research Database (Denmark)

    Carlsen, Berit Christina; Andersen, Klaus Ejner; Menné, Torkil

    2009-01-01

    for polysensitization, including atopic eczema. METHODS: A questionnaire case-control study of 562 polysensitized and 1124 single/double-sensitized individuals was performed. RESULTS: The results show that 45% of polysensitized and 31% of single/double-sensitized patients had or had had atopic eczema, and atopic eczema...... the group of patients with atopic eczema and the group without atopic eczema. CONCLUSION: Patients with atopic eczema were overrepresented in the group of polysensitized patients and polysensitized patients should be viewed in the light of occurrence or lack of atopic eczema....

  6. Multi-analytical characterization of archaeological ceramics. A case study from the Sforza Castle (Milano, Italy).

    Science.gov (United States)

    Barberini, V.; Maspero, F.; Galimberti, L.; Fusi, N.

    2009-04-01

    The aim of this work was the characterization, using several analytical techniques, of a sample of ancient pottery found during archaeological excavations in the 14th century's Sforza Castle in Milano. The use of a multi-analytical approach is well established in the study of archaeological materials (e.g. Tite et al. 1984, Ribechini et al. 2008). The chemical composition of the sample was determined with X-ray fluorescence spectroscopy. The chemical composition is: SiO2 61.3(±3)%, Al2O3 22.5(±2)%, Fe2O3 7.19(±6)%, K2O 3.85(±1)%, MgO 1.6(±1)%, Na2O 1.6(±4)% (probably overestimated), TiO2 1.02(±2)%, CaO 0.93(±1)%, MnO 0.15(±1)% and P2O5 0.06(±2)%. The K2O content, important when dealing with TL dating, was determined also with atomic absorption spectrophotometry. The K2O content determined with atomic absorption is 3.86(±3)%, in agreement with X-ray fluorescence analysis. The mineralogical composition of the sample was determined with X-ray powder diffraction: quartz 59.6(±1) wt%, mica 37.8(±3) wt% and feldspar (plagioclase) 2.6(±2) wt%. The sample homogeneity was assessed with X-ray computerised tomography (CT), which is a very powerful non-destructive analysis tool for 3D characterization (Sèguin, 1991). CT images show differences in materials with different X-ray absorption (mainly depending on different densities) and 3D reconstruction has many interesting archaeological applications (e.g. study of sealed jars). CT images of the studied sample showed the presence of angular fragments (probably quartz) few millimetres wide immersed in a fine grained matrix. Moreover, before and after the CT analysis, some ceramic powder was sampled to perform thermoluminescence analysis (TL, the powder used for this analysis can not be recovered). It was thus possible to evaluate the dose absorbed by the material due the X-ray irradiation. The dose absorbed after 3 hours of irradiation, the time needed for a complete scan of a 7 x 5 x 1 cm, is about 100 Gy, which

  7. Characterization and aerobic biological treatment of msw: a case study of hyderabad city

    International Nuclear Information System (INIS)

    Korai, M.S.; Mahar, R.B.

    2014-01-01

    This study was conducted to assess the MSW (Municipal Solid Waste) generated in Hyderabad city for its suitability to make compost product through AB (Aerobic Biological) treatment. Assessment of MSW regarding its generation rate, quantification and characterization decides its suitability for composting process. Three AB treatment reactors R1 (natural air circulation and manually mixed reactor), R2 (compressed air circulation and manually mixed reactor) and R3 (compressed air circulation and mechanically mixed reactor) were designed and fabricated. AB treatment of the segregated food and yard waste reveals that there is no any significant change occurs in the moisture content of the compost product in all the reactors but, significant loss of VS (Volatile Solids) and gain of ash content was observed for reactor R2. Thus, the reactor R2 is the most efficient reactor in comparison to other reactors. Moreover, the mechanical mixing in AB treatment does not significantly increase VS loss. Further the reactor R1 does not consumes electricity and thus can be employed as the solution for converting segregated food and yard waste from MSW into a compost product. (author)

  8. Characterization of pica and chewing behaviors in privately owned cats: a case-control study.

    Science.gov (United States)

    Demontigny-Bédard, Isabelle; Beauchamp, Guy; Bélanger, Marie-Claude; Frank, Diane

    2016-08-01

    The aim of this study was to characterize pica behavior in cats. Cat owners were recruited to participate in a questionnaire survey on pica behavior exhibited by their cats. Emphasis was put on the type of item ingested. Questions on early history and environment, as well as general health and gastrointestinal signs, were asked. Owners of healthy cats not showing pica were also recruited into a control group. Associations between variables and groups were statistically tested. Pica was directed most commonly at shoelaces or threads, followed by plastic, fabric, other items, rubber, paper or cardboard and wood. Some cats ingested specific items but only chewed others. A significant positive association was found between sucking and ingesting fabric (P = 0.002). Ad libitum feeding was significantly lower in the pica group than the control group (P = 0.01). Prevalence of self-sucking behavior was significantly higher in the pica group than the control group (P = 0.001). Cats with pica vomited significantly more often than control cats (P = 0.01). Pica, the ingestion of inedible items, does not seem to be the consequence of a suboptimal environment or early weaning. Cats with pica were less commonly fed ad libitum than healthy cats. As frequently reported, pica and vomiting were related, but the causative association is not well established and thus warrants further investigation. © The Author(s) 2015.

  9. Characterization and Aerobic Biological Treatment of MSW: A Case Study of Hyderabad City

    Directory of Open Access Journals (Sweden)

    Muhammad Safar Korai

    2014-07-01

    Full Text Available This study was conducted to assess the MSW (Municipal Solid Waste generated in Hyderabad city for its suitability to make compost product through AB (Aerobic Biological treatment. Assessment of MSW regarding its generation rate, quantification and characterization decides its suitability for composting process. Three AB treatment reactors R1 (natural air circulation and manually mixed reactor, R2 (compressed air circulation and manually mixed reactor and R3 (compressed air circulation and mechanically mixed reactor were designed and fabricated. AB treatment of the segregated food and yard waste reveals that there is no any significant change occurs in the moisture content of the compost product in all the reactors but, significant loss of VS (Volatile Solids and gain of ash content was observed for reactor R2. Thus, the reactor R2 is the most efficient reactor in comparison to other reactors. Moreover, the mechanical mixing in AB treatment does not significantly increase VS loss. Further the reactor R1 does not consumes electricity and thus can be employed as the solution for converting segregated food and yard waste from MSW into a compost product

  10. Immunohistochemical characterization of glandular elements in glandular cardiac myxoma: Study of six cases

    Directory of Open Access Journals (Sweden)

    Devajit Nath

    2017-01-01

    Full Text Available Back ground: Glandular cardiac myxoma has varying clinical presentation with uncertain histogenesis and debatable immunohistochemical profile. Glandular epithelial differentiations are rare phenomenon known to be present as an intrinsic component of the tumor. The origin of the glands has been attributed to epithelial differentiation of a totipotent cardiomyogenic precursor cells or the entrapped foregut rests in the tumor. Materials and Methods: Retrospective study includes six cases of glandular cardiac myxoma collected over a perior of 4 years. Sections were examined to define the histogenesis, histological and immunohistochemical profile of the glandular elements. Results: Incidence of glandular cardiac myxoma was 6.6% with a male to female ratio of 1:2.Mean age was 49.9 years. Left atrium was the commonest site. Five were sporadic and one was familial. Chest pain and dyspnea were the commonest clinical symptoms. Histologically all myxoma showed well formed glandular structures with typical myxomatous area. No atypia, mitosis or necrosis was identified in the glandular elements. Markers in six cases of glandular cardiac myxoma were immunopositive for CK7, CK 19, EMA, CEA, focally for E-cadherin while immunonegative for CK20, Chromogranin, Synaptophysin, calretenin, vimentin, B-catenin, TTF-1 and GCDFP-15 favoring enteric differentiation. Conclusion: Glandular cardiac myxoma is a rare entity which shows characteristics similar to those of classical cardiac myxoma with benign glandular elements showing enteric differentiation. Complete surgical excision is the treatment of choice with good prognosis. It is important to recognize this entity to avoid an erroneous diagnosis of metastatic adenocarcinoma.

  11. HYDROGEOLOGIC CASE STUDIES

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  12. Characterizing semantic mappings adaptation via biomedical KOS evolution: a case study investigating SNOMED CT and ICD.

    Science.gov (United States)

    Dos Reis, Julio Cesar; Pruski, Cédric; Da Silveira, Marcos; Reynaud-Delaître, Chantal

    2013-01-01

    Mappings established between Knowledge Organization Systems (KOS) increase semantic interoperability between biomedical information systems. However, biomedical knowledge is highly dynamic and changes affecting KOS entities can potentially invalidate part or the totality of existing mappings. Understanding how mappings evolve and what the impacts of KOS evolution on mappings are is therefore crucial for the definition of an automatic approach to maintain mappings valid and up-to-date over time. In this article, we study variations of a specific KOS complex change (split) for two biomedical KOS (SNOMED CT and ICD-9-CM) through a rigorous method of investigation for identifying and refining complex changes, and for selecting representative cases. We empirically analyze and explain their influence on the evolution of associated mappings. Results point out the importance of considering various dimensions of the information described in KOS, like the semantic structure of concepts, the set of relevant information used to define the mappings and the change operations interfering with this set of information.

  13. Synthesis and Characterization of Quantum Dots: A Case Study Using PbS

    Science.gov (United States)

    Pan, Yi; Li, Yue Ru; Zhao, Yu; Akins, Daniel L.

    2015-01-01

    A research project for senior undergraduates of chemistry has been developed to introduce syntheses of a series of monodispersed semiconductor PbS quantum dots (QDs) and their characterization methodologies. In this paper, we report the preparation of monodispersed semiconductor PbS QDs with sizes smaller than the exciton Bohr radius using a…

  14. CASE STUDY

    African Journals Online (AJOL)

    2011-06-02

    Jun 2, 2011 ... immunosuppression associated with HIV/AIDS puts them at a higher risk of developing oesophageal cancer. 47. CASE STUDY. A 49-year-old man was diagnosed as HIV infected, with a CD4 count of 60 cells/µl. He was started on an antiretroviral treatment regimen comprising zidovudine, lamivudine and ...

  15. Using high-density magnetic and electromagnetic data for waste site characterization: A case study

    International Nuclear Information System (INIS)

    Cochran, J.R.; Dalton, K.E.

    1995-01-01

    Magnetometers are frequently used to characterize hazardous waste sites. Due to cost and time considerations, data are typically collected on a coarse grid with nodes on 3 to 6 meter (m) centers. Hardware and software are now available which allow the rapid and cost effective collection of information on a much finer sampling grid. In this paper we present and compare total field magnetometery data collected on 3 m centers to total field magnetometery data collected on a grid with centers of 0.5 m or less. We also compare the magnetometery data to time-domain electromagnetic (EM) data collected on a 1 m by 0.2 m grid using the recently introduced Geonics Ltd. EM61 metal detector. All three data sets were collected at an abandoned landfill radioactive Burial Site No. 11 (RB-11) is located on Kirtland Air Force Base near Albuquerque, New Mexico

  16. Characterization of a Flood Event through a Sediment Analysis: The Tescio River Case Study

    Directory of Open Access Journals (Sweden)

    Silvia Di Francesco

    2016-07-01

    Full Text Available This paper presents the hydrological analysis and grain size characteristics of fluvial sediments in a river basin and their combination to characterize a flood event. The overall objective of the research is the development of a practical methodology based on experimental surveys to reconstruct the hydraulic history of ungauged river reaches on the basis of the modifications detected on the riverbed during the dry season. The grain size analysis of fluvial deposits usually requires great technical and economical efforts and traditional sieving based on physical sampling is not appropriate to adequately represent the spatial distribution of sediments in a wide area of a riverbed with a reasonable number of samples. The use of photographic sampling techniques, on the other hand, allows for the quick and effective determination of the grain size distribution, through the use of a digital camera and specific graphical algorithms in large river stretches. A photographic sampling is employed to characterize the riverbed in a 3 km ungauged reach of the Tescio River, a tributary of the Chiascio River, located in central Italy, representative of many rivers in the same geographical area. To this end, the particle size distribution is reconstructed through the analysis of digital pictures of the sediments taken on the riverbed in dry conditions. The sampling has been performed after a flood event of known duration, which allows for the identification of the removal of the armor in one section along the river reach under investigation. The volume and composition of the eroded sediments made it possible to calculate the average flow rate associated with the flood event which caused the erosion, by means of the sediment transport laws and the hydrological analysis of the river basin. A hydraulic analysis of the river stretch under investigation was employed to verify the validity of the proposed procedure.

  17. Characterizing drought in terms of changes in the precipitation-runoff relationship: a case study of the Loess Plateau, China

    Science.gov (United States)

    Zhang, Yuan; Feng, Xiaoming; Wang, Xiaofeng; Fu, Bojie

    2018-03-01

    The frequency and intensity of drought are increasing dramatically with global warming. However, few studies have characterized drought in terms of its impacts on ecosystem services, the mechanisms through which ecosystems support life. As a result, little is known about the implications of increased drought for resource management. This case study characterizes drought by linking climate anomalies with changes in the precipitation-runoff relationship (PRR) on the Loess Plateau of China, a water-limited region where ongoing revegetation makes drought a major concern. We analyzed drought events with drought durations ≥ 5 years and mean annual precipitation anomaly (PA) values ≤ -5 % during drought periods. The results show that continuous precipitation shifts are able to change the water balance of watersheds in water-limited areas, and multi-year drought events cause the PRR to change with a significantly decreasing trend (p runoff ratio decreased from 10 to 6.8 % during 1991-1999. The joint probability and return period gradually increase with increasing of drought duration and severity. The ecosystem service of water yield is easily affected by drought events with durations equal to or greater than 6 years and drought severity values equal to or greater than 0.55 (precipitation ≤ 212 mm). At the same time, multi-year drought events also lead to significant changes in the leaf area index (LAI). Such studies are essential for ecosystem management in water-limited areas.

  18. Technological characterization of a mineral deposit. A case study: the niobium of Catalao I, Goias State, Brazil

    International Nuclear Information System (INIS)

    Sant'Agostino, Lilia Mascarenhas

    1996-01-01

    This thesis presents a contribution to the subject of ore technological characterization integrated to orebody context, regarding sample, ore characteristics, ore types definition and distribution through the mineral occurrence, and ore reserves modeling using technological parameters. A professional experience in this specialization based a conceptual discussion of the matter, supported by a practical approach. The initial approach is the subject definition, and it's importance for technological and economical feasibility studies, in all phases of mining research and development, as a tool for beneficiation alternatives definition. The multidisciplinary aspect of the knowledge involved for ore characterization is remarked, considering that is an interface segment to be conduced interactively with others. It is an applied mineralogy, that needs some geological and some ore dressing imputes. After the general considerations about importance and applicability, it follows a methodological approach of laboratory procedures and analytical techniques, as a result of practical experience acquired in the study of several ores. The main points discussed are related with criterion to organized laboratory preparation scheme and to select appropriated analytical techniques, without detailing them, for what some specialized bibliography is indicated. Finalizing the theoretical explanation, there is a concise description about computers resources for 3D orebody modeling, and integrated software applied for geology and mining. For illustration, it is exposed a complex ore case study: niobium mineralization associated with the alkaline-carbonatitic occurrence of Catalao I, located in Goias State, Brazil. Besides the explanation of laboratory procedures and methods applied, results treatment and interpretation are emphasized, under both characterization and economic point of view. (author)

  19. Characterization of Portuguese Centenarian Eating Habits, Nutritional Biomarkers, and Cardiovascular Risk: A Case Control Study

    Directory of Open Access Journals (Sweden)

    A. Pereira da Silva

    2018-01-01

    Full Text Available Background and Aims. Eating habits may contribute to longevity. We characterized the eating habits and cardiovascular risk (CVR biomarkers in Portuguese centenarians (CENT compared to controls. Methods and Results. Centenarians (n=253, 100.26 ± 1.98 years, were compared with 268 controls (67.51 ± 3.25, low (LCR and high (HCR CVR (QRISK®2-2016. Anthropometric and body composition were evaluated by bioimpedance. Abdominal obesity, BMI, and fat mass (FM cut-offs were according to the WHO. Sarcopenia was defined by muscle mass index cut-off ≤ 16.7 kg/m2. Daily red meat intake, adjusted for age and gender, was sarcopenia protective (OR = 0.25, 95% CI = 0.096–0.670, P=0.006; however, it contributes for FM excess (OR = 4.946, 95% CI = 1.471–16.626, P=0.01, overweight, and obesity (OR = 4.804, 95% CI = 1.666–13.851, P=0.004. This centenarian eating habit (2% contrasts to HCR (64.3%. The history of red meat (P<0.0001 and canned/industrialized food intakes (P<0.0001 was associated with HCR. Basal metabolism was lower in centenarians versus LCR/HCR (CENT = 1176.78 ± 201.98; LCR = 1356.54 ± 170.65; HCR = 1561.33 ± 267.85; P<0.0001, BMI (CENT = 21.06 ± 3.68; LCR = 28.49 ± 4.69; HCR = 29.56 ± 5.26; P<0.0001, waist circumference (CENT = 85.29 ± 10.83; LCR = 96.02 ± 11.71; HCR = 104.50 ± 11.84; P<0.0001, and waist-hip ratio (CENT = 0.88 ± 0.07; LCR = 0.92 ± 0.08; HCR = 1.01 ± 0.08; P<0.0001. CENT had lower total cholesterol, LDL cholesterol, non-HDL cholesterol, and cholesterol/HDL ratio than controls. Conclusions. Frequent consumption of red meat, cholesterol, and heme iron rich may contribute to obesity and increased CVR. The low frequency of this consumption, observed in centenarians, although associated with sarcopenia, may be one of the keys to longevity.

  20. Ecosystem characterization strategy at a repository site - Olkiluoto as a case study

    Energy Technology Data Exchange (ETDEWEB)

    Pere, Tuomas [Posiva Oy, Olkiluoto, 27160 Eurajoki (Finland); Kangasniemi, Ville [Environmental Research and Assessment EnviroCase, Ltd., Hallituskatu 1 D 4, 28100 Pori (Finland); Lahdenperae, Anne-Maj [Saanio and Riekkola Oy, Laulukuja 4, 00420 Helsinki (Finland); Aro, Lasse [Finnish Forest Research Institute, Kaironiementie 15, 39700 Parkano (Finland)

    2014-07-01

    and mires. The reference area used by Posiva covers a large area in the southwestern Finland. Accumulation of radionuclides to surface environment and biosphere, including humans is finally modelled biotope and species-specifically by using several calculation cases representing different scenarios for radionuclide release and transport. The end product is a scientifically justified concept of possible doses to the environment, plants, animals and finally humans. This is used in the evaluation of the long-term effects of the project of final disposal of high-level radioactive waste. (authors)

  1. Characterization and comparability of biosimilars: A filgrastim case of study and regulatory perspectives for Latin America

    Directory of Open Access Journals (Sweden)

    Karina Mendoza-Macedo

    2016-11-01

    Conclusions: This approach provides support to diminish uncertainty of exhibiting different pharmacological profiles and narrows or even avoids the necessity of comparative clinical studies. Ultimately, this proposal is intended to improve the accessibility to high quality biosimilars in Latin America and other developing countries.

  2. Dental solid waste characterization and management in Iran: a case study of Sistan and Baluchestan Province.

    Science.gov (United States)

    Bazrafshan, Edris; Mohammadi, Leili; Mostafapour, Ferdos Kord; Moghaddam, Alireza Ansari

    2014-02-01

    The management of dental solid waste continues to be a major challenge, particularly in most healthcare facilities of the developing world. In Iran, few studies on management of dental solid waste and its composition are available. An effort has been made through this study to evaluate the hazardous and infectious status of dental solid waste, keeping in mind its possible role in cross-infection chain. For this study, 123 private dental centres and 36 public dental centres were selected and the composition and generation rate of dental solid waste produced were measured. Dental solid waste was classified to four main categories: (i) domestic-type; (ii) potentially infectious; (iii) chemical and pharmaceutical; and (iv) toxic, which constituted 11.7, 80.3, 6.3, and 1.7%, respectively, of the total. Also, the results indicated that the dental solid waste per patient per day generation rate for total, domestic-type, potentially infectious, chemical and pharmaceutical, and toxic wastes were 169.9, 8.6, 153.3, 11.2, and 3.3 g/patient/d, respectively. Furthermore, the per day generation rates for total, domestic-type, potentially infectious, chemical and pharmaceutical, and toxic wastes were 194.5, 22.6, 156.1, 12.3, and 3.4 kg/d, respectively. According to findings of this study, for best management of dental waste it is suggested that source reduction, separation, reuse, and recycling programmes be implemented and each section of dental waste be collected and disposed of separately and in accordance with related criteria.

  3. Clinical characterization of women with burning mouth syndrome in a case-control study.

    Science.gov (United States)

    Acharya, Shikha; Carlén, Anette; Wenneberg, Bengt; Jontell, Mats; Hägglin, Catharina

    2018-05-01

    Burning mouth syndrome (BMS) is a chronic orofacial pain disorder that is defined by a burning sensation in the oral mucosa. The aim of this study was to investigate the underlying factors, clinical characteristics and self-reported oral and general health factors associated with BMS. Fifty-six women with BMS (mean age: 67.7) and their age-matched controls were included in the study. A general questionnaire, an OHRQL index and BMS-specific questionnaires were used. Each subject underwent an oral examination. The mean severity of the BMS symptoms (VAS, 0-100) was 66.2 (SD 19.7). Overall, 45% of the patients reported taste disturbances. More of the patients than the controls rated their general health, oral health and life situation as 'less satisfactory'. The patients also reported more frequently on-going medications, diseases/disorders, xerostomia, allergy and skin diseases. Except for more bruxofacets among the patients, there were no significant differences regarding signs of parafunction. In a multiple logistic regression analysis, xerostomia and skin diseases showed the strongest prediction for BMS and no significant effect was found for medication, allergy or bruxofacets. Skin diseases and xerostomia but not parafunction were strongly associated with BMS. Our findings provide the basis for additional studies to elucidate the causal factors of BMS.

  4. A Risk Management Framework to Characterize Black Swan Risks: A Case Study of Lightning Effects on Insensitive High Explosives

    Science.gov (United States)

    Sanders, Gary A.

    Effective and efficient risk management processes include the use of high fidelity modeling and simulation during the concept exploration phase as part of the technology and risk assessment activities, with testing and evaluation tasks occurring in later design development phases. However, some safety requirements and design architectures may be dominated by the low probability/high consequence "Black Swan" vulnerabilities that require very early testing to characterize and efficiently mitigate. Failure to address these unique risks has led to catastrophic systems failures including the space shuttle Challenger, Deepwater Horizon, Fukushima nuclear reactor, and Katrina dike failures. Discovering and addressing these risks later in the design and development process can be very costly or even lead to project cancellation. This paper examines the need for risk management process adoption of early hazard phenomenology testing to inform the technical risk assessment, requirements definition and conceptual design. A case study of the lightning design vulnerability of the insensitive high explosives being used in construction, mining, demolition, and defense industries will be presented to examine the impact of this vulnerability testing during the concept exploration phase of the design effort. While these insensitive high explosives are far less sensitive to accidental initiation by fire, impact, friction or even electrical stimuli, their full range of sensitivities have not been characterized and ensuring safe engineering design and operations during events such as lightning storms requires vulnerability testing during the risk assessment phase.

  5. A case study characterizing animal fecal sources in surface water using a mitochondrial DNA marker.

    Science.gov (United States)

    Bucci, John P; Shattuck, Michelle D; Aytur, Semra A; Carey, Richard; McDowell, William H

    2017-08-01

    Water quality impairment by fecal waste in coastal watersheds is a public health issue. The present study provided evidence for the use of a mitochondrial (mtDNA) marker to detect animal fecal sources in surface water. The accurate identification of fecal pollution is based on the notion that fecal microorganisms preferentially inhabit a host animal's gut environment. In contrast, mtDNA host-specific markers are inherent to eukaryotic host cells, which offers the advantage by detecting DNA from the host rather than its fecal bacteria. The present study focused on sampling water presumably from non-point sources (NPS), which can increase bacterial and nitrogen concentrations to receiving water bodies. Stream sampling sites located within the Piscataqua River Watershed (PRW), New Hampshire, USA, were sampled from a range of sites that experienced nitrogen inputs such as sewer and septic systems and suburban runoff. Three mitochondrial (mtDNA) gene marker assays (human, bovine, and canine) were tested from surface water. Nineteen sites were sampled during an 18-month period. Analyses of the combined single and multiplex assay results showed that the proportion of occurrence was highest for bovine (15.6%; n = 77) compared to canine (5.6%; n = 70) and human (5.7%; n = 107) mtDNA gene markers. For the human mtDNA marker, there was a statistically significant relationship between presence vs. absence and land use (Fisher's test p = 0.0031). This result was evident particularly for rural suburban septic, which showed the highest proportion of presence (19.2%) compared to the urban sewered (3.3%), suburban sewered (0%), and agricultural (0%) as well as forested septic (0%) sites. Although further testing across varied land use is needed, our study provides evidence for using the mtDNA marker in large watersheds.

  6. Media portrayals and health inequalities: a case study of characterizations of Gene x Environment interactions.

    Science.gov (United States)

    Horwitz, Allan V

    2005-10-01

    This article examines how genetic and environmental interactions associated with health inequalities are constructed and framed in the presentation of scientific research. It uses the example of a major article about depression in a longitudinal study of young adults that appeared in Science in 2003. This portrayal of findings related to health inequalities uses a genetic lens that privileges genetic influences and diminishes environmental ones. The emphasis on the genetic side of Gene x Environment interactions can serve to deflect attention away from the important impact of social inequalities on health.

  7. Household hazardous waste quantification, characterization and management in China's cities: a case study of Suzhou.

    Science.gov (United States)

    Gu, Binxian; Zhu, Weimo; Wang, Haikun; Zhang, Rongrong; Liu, Miaomiao; Chen, Yangqing; Wu, Yi; Yang, Xiayu; He, Sheng; Cheng, Rong; Yang, Jie; Bi, Jun

    2014-11-01

    A four-stage systematic tracking survey of 240 households was conducted from the summer of 2011 to the spring of 2012 in a Chinese city of Suzhou to determine the characteristics of household hazardous waste (HHW) generated by the city. Factor analysis and a regression model were used to study the major driving forces of HHW generation. The results indicate that the rate of HHW generation was 6.16 (0.16-31.74, 95% CI) g/person/day, which accounted for 2.23% of the household solid waste stream. The major waste categories contributing to total HHW were home cleaning products (21.33%), medicines (17.67%) and personal care products (15.19%). Packaging and containers (one-way) and products (single-use) accounted for over 80% of total HHW generation, implying a considerable potential to mitigate HHW generation by changing the packaging design and materials used by manufacturing enterprises. Strong correlations were observed between HHW generation (g/person/day) and the driving forces group of "household structure" and "consumer preferences" (among which the educational level of the household financial manager has the greatest impact). Furthermore, the HHW generation stream in Suzhou suggested the influence of another set of variables, such as local customs and culture, consumption patterns, and urban residential life-style. This study emphasizes that HHW should be categorized at its source (residential households) as an important step toward controlling the HHW hazards of Chinese cities. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Casing study

    Energy Technology Data Exchange (ETDEWEB)

    Roche, P.

    2000-12-01

    An unorthodox method of casing drilling used by Tesco Corporation at a gas well in Wyoming to drill deeper using casings as drillpipe is discussed. The process involves either rotating the casing as drill string or using a downhole mud motor to rotate the bit. In this instance, the surface hole and the production hole were casing-drilled to a record 8,312 feet by rotating the casing. The 8 1/2-inch surface hole was drilled with 7-inch casing to 1,200 feet using a Tesco underreamer and a polycrystalline pilot bit; drilling and cementing was completed in 12 1/2 hours. The 6 1/4-inch production hole was drilled with 4 1/2-inch casing and the bottomhole assembly was retrieved after 191 hours rotating. This case was the first in which the entire well was casing-drilled from surface to TD. Penetration rate compared favorably with conventional methods: 12 1/2 hours for casing-drilling to 18.9 hours for conventional drilling, despite the fact that the casing-drilling technology is still in its infancy. It is suggested that casing-drilling has the potential to eliminate the need for the drillpipe entirely. If these expectations were to be realised, casing-drilling could be one of the most radical drilling changes in the history of the oil and gas industry. 1 photo.

  9. Characterization of Drought Development through Remote Sensing: A Case Study in Central Yunnan, China

    Directory of Open Access Journals (Sweden)

    Sawaid Abbas

    2014-05-01

    Full Text Available This study assesses the applicability of remote sensing data for retrieval of key drought indicators including the degree of moisture deficiency, drought duration and areal extent of drought within different land cover types across the landscape. A Normalized Vegetation Supply Water Index (NVSWI is devised, combining remotely sensed climate data to retrieve key drought indicators over different vegetation cover types and a lag-time relationship is established based on preceding rainfall. The results indicate that during the major drought event of spring 2010, Evergreen Forest (EF experienced severe dry conditions for 48 days fewer than Cropland (CL and Shrubland (SL. Testing of vegetation response to drought conditions with different lag-time periods since the last rainfall indicated a highest correlation for CL and SL with the 4th lag period (i.e., 64 days whereas EF exhibited maximum correlation with the 5th lag period (i.e., 80 days. Evergreen Forest, which includes tree crops, appears to act as a green reservoir of water, and is more resistant than CL and SL to drought due to its water retention capacity with deeper roots to tap sub-surface water. Identifying differences in rainfall lag-time relationships among land cover types using a remote sensing-based integrated drought index enables more accurate drought prediction, and can thus assist in the development of more specific drought adaptation strategies.

  10. Radiance Assimilation Shows Promise for Snowpack Characterization: A 1-D Case Study

    Science.gov (United States)

    Durand, Michael; Kim, Edward; Margulis, Steve

    2008-01-01

    We demonstrate an ensemble-based radiometric data assimilation (DA) methodology for estimating snow depth and snow grain size using ground-based passive microwave (PM) observations at 18.7 and 36.5 GHz collected during the NASA CLPX-1, March 2003, Colorado, USA. A land surface model was used to develop a prior estimate of the snowpack states, and a radiative transfer model was used to relate the modeled states to the observations. Snow depth bias was -53.3 cm prior to the assimilation, and -7.3 cm after the assimilation. Snow depth estimated by a non-DA-based retrieval algorithm using the same PM data had a bias of -18.3 cm. The sensitivity of the assimilation scheme to the grain size uncertainty was evaluated; over the range of grain size uncertainty tested, the posterior snow depth estimate bias ranges from -2.99 cm to -9.85 cm, which is uniformly better than both the prior and retrieval estimates. This study demonstrates the potential applicability of radiometric DA at larger scales.

  11. Characterizing International Travel Behavior from Geotagged Photos: A Case Study of Flickr.

    Science.gov (United States)

    Yuan, Yihong; Medel, Monica

    2016-01-01

    Recent advances in multimedia and mobile technologies have facilitated large volumes of travel photos to be created and shared online. Although previous studies have utilized geotagged photos to model travel patterns at individual locations, there is limited research on how these datasets can model international travel behavior and inter-country travel flows-a crucial indicator to quantify the interactions between countries in tourism economics. Realizing the necessity to investigate the potential of geotagged photos in tourism geography, this research investigates international travel patterns from two perspectives: 1) We apply a series of indicators (radius of gyration (ROG), number of countries visited, and entropy) to measure the descriptive characteristics of international travel in different countries; 2) By constructing a gravity model of trade, we investigate how distance decay influences the magnitude of international travel flow between geographic entities, and whether (or how much) the popularity of a given destination (defined as the percentage of tourist income in national gross domestic product (GDP)) affects travel choices in different countries. The results provide valuable input to various commercial applications such as individual travel planning and destination suggestions.

  12. Femtosecond laser machining for characterization of local mechanical properties of biomaterials: a case study on wood

    Science.gov (United States)

    Jakob, Severin; Pfeifenberger, Manuel J.; Hohenwarter, Anton; Pippan, Reinhard

    2017-12-01

    The standard preparation technique for micro-sized samples is focused ion beam milling, most frequently using Ga+ ions. The main drawbacks are the required processing time and the possibility and risks of ion implantation. In contrast, ultrashort pulsed laser ablation can process any type of material with ideally negligible damage to the surrounding volume and provides 4 to 6 orders of magnitude higher ablation rates than the ion beam technique. In this work, a femtosecond laser was used to prepare wood samples from spruce for mechanical testing at the micrometre level. After optimization of the different laser parameters, tensile and compressive specimens were produced from microtomed radial-tangential and longitudinal-tangential sections. Additionally, laser-processed samples were exposed to an electron beam prior to testing to study possible beam damage. The specimens originating from these different preparation conditions were mechanically tested. Advantages and limitations of the femtosecond laser preparation technique and the deformation and fracture behaviour of the samples are discussed. The results prove that femtosecond laser processing is a fast and precise preparation technique, which enables the fabrication of pristine biological samples with dimensions at the microscale.

  13. Characterizing the Land Shareholding Cooperative: A Case Study of Shanglin Village in Jiangsu, China

    Directory of Open Access Journals (Sweden)

    Yi Ren

    2017-07-01

    Full Text Available The land tenure reform is the key to sustainable development in rural China. Without challenging the collective ownership of land, the land shareholding cooperative (LSC system came into being and is being strongly endorsed by the authority: It re-collectivizes the contracted land from peasants and enables better regional planning and large-scale modern agricultural production. This paper studies a specific LSC (Shanglin LSC in the Sunan region of the Yangtze River Delta based on our fieldwork. We found that the LSC system is a bottom-up institutional innovation towards sustainable land use in China. Both village cadres and ordinary peasants’ decision making contributes to its successful establishment and development. This shareholding system increases peasants’ income through dividends and employment opportunities. The concentrated land enables ecological farming. Acting as a quasi-government agency, the LSC also provides public service and social security to the village community. On the other hand, the LSCs’ success depends on certain prior conditions and the LSCs’ multiple missions may contradict each other from time to time, and lead to loss of efficiency. We argue that this approach to land tenure reform may not be universally applied to any regions in China.

  14. Characterizing International Travel Behavior from Geotagged Photos: A Case Study of Flickr.

    Directory of Open Access Journals (Sweden)

    Yihong Yuan

    Full Text Available Recent advances in multimedia and mobile technologies have facilitated large volumes of travel photos to be created and shared online. Although previous studies have utilized geotagged photos to model travel patterns at individual locations, there is limited research on how these datasets can model international travel behavior and inter-country travel flows-a crucial indicator to quantify the interactions between countries in tourism economics. Realizing the necessity to investigate the potential of geotagged photos in tourism geography, this research investigates international travel patterns from two perspectives: 1 We apply a series of indicators (radius of gyration (ROG, number of countries visited, and entropy to measure the descriptive characteristics of international travel in different countries; 2 By constructing a gravity model of trade, we investigate how distance decay influences the magnitude of international travel flow between geographic entities, and whether (or how much the popularity of a given destination (defined as the percentage of tourist income in national gross domestic product (GDP affects travel choices in different countries. The results provide valuable input to various commercial applications such as individual travel planning and destination suggestions.

  15. Characterizing drought in terms of changes in the precipitation–runoff relationship: a case study of the Loess Plateau, China

    Directory of Open Access Journals (Sweden)

    Y. Zhang

    2018-03-01

    Full Text Available The frequency and intensity of drought are increasing dramatically with global warming. However, few studies have characterized drought in terms of its impacts on ecosystem services, the mechanisms through which ecosystems support life. As a result, little is known about the implications of increased drought for resource management. This case study characterizes drought by linking climate anomalies with changes in the precipitation–runoff relationship (PRR on the Loess Plateau of China, a water-limited region where ongoing revegetation makes drought a major concern. We analyzed drought events with drought durations  ≥  5 years and mean annual precipitation anomaly (PA values  ≤  −5 % during drought periods. The results show that continuous precipitation shifts are able to change the water balance of watersheds in water-limited areas, and multi-year drought events cause the PRR to change with a significantly decreasing trend (p < 0.05 compared to other historical records. For the Loess Plateau as a whole, the average runoff ratio decreased from 10 to 6.8  % during 1991–1999. The joint probability and return period gradually increase with increasing of drought duration and severity. The ecosystem service of water yield is easily affected by drought events with durations equal to or greater than 6 years and drought severity values equal to or greater than 0.55 (precipitation  ≤  212 mm. At the same time, multi-year drought events also lead to significant changes in the leaf area index (LAI. Such studies are essential for ecosystem management in water-limited areas.

  16. CASE STUDY

    African Journals Online (AJOL)

    HIV infection has several oral manifestations, including oral candidiasis and oral hairy leucoplakia. Occasionally unusual presentations requiring rigorous investigations are seen, and in these cases the diagnosis sometimes remains a dilemma owing to limited investigation facilities.1-3 We present the case of a patient who.

  17. Characterization of Peripheral Immune Cell Subsets in Patients with Acute and Chronic Cerebrovascular Disease: A Case-Control Study

    Directory of Open Access Journals (Sweden)

    Peter Kraft

    2015-10-01

    Full Text Available Immune cells (IC play a crucial role in murine stroke pathophysiology. However, data are limited on the role of these cells in ischemic stroke in humans. We therefore aimed to characterize and compare peripheral IC subsets in patients with acute ischemic stroke/transient ischemic attack (AIS/TIA, chronic cerebrovascular disease (CCD and healthy volunteers (HV. We conducted a case-control study of patients with AIS/TIA (n = 116 or CCD (n = 117, and HV (n = 104 who were enrolled at the University Hospital Würzburg from 2010 to 2013. We determined the expression and quantity of IC subsets in the three study groups and performed correlation analyses with demographic and clinical parameters. The quantity of several IC subsets differed between the AIS/TIA, CCD, and HV groups. Several clinical and demographic variables independently predicted the quantity of IC subsets in patients with AIS/TIA. No significant changes in the quantity of IC subsets occurred within the first three days after AIS/TIA. Overall, these findings strengthen the evidence for a pathophysiologic role of IC in human ischemic stroke and the potential use of IC-based biomarkers for the prediction of stroke risk. A comprehensive description of IC kinetics is crucial to enable the design of targeted treatment strategies.

  18. Landslide Mapping and Characterization through Infrared Thermography (IRT: Suggestions for a Methodological Approach from Some Case Studies

    Directory of Open Access Journals (Sweden)

    William Frodella

    2017-12-01

    Full Text Available In this paper, the potential of Infrared Thermography (IRT as a novel operational tool for landslide surveying, mapping and characterization was tested and demonstrated in different case studies, by analyzing various types of instability processes (rock slide/fall, roto-translational slide-flow. In particular, IRT was applied, both from terrestrial and airborne platforms, in an integrated methodology with other geomatcs methods, such as terrestrial laser scanning (TLS and global positioning systems (GPS, for the detection and mapping of landslides’ potentially hazardous structural and morphological features (structural discontinuities and open fractures, scarps, seepage and moisture zones, landslide drainage network and ponds. Depending on the study areas’ hazard context, the collected remotely sensed data were validated through field inspections, with the purpose of studying and verifying the causes of mass movements. The challenge of this work is to go beyond the current state of the art of IRT in landslide studies, with the aim of improving and extending the investigative capacity of the analyzed technique, in the framework of a growing demand for effective Civil Protection procedures in landslide geo-hydrological disaster managing activities. The proposed methodology proved to be an effective tool for landslide analysis, especially in the field of emergency management, when it is often necessary to gather all the required information in dangerous environments as fast as possible, to be used for the planning of mitigation measures and the evaluation of hazardous scenarios. Advantages and limitations of the proposed method in the field of the explored applications were evaluated, as well as general operative recommendations and future perspectives.

  19. case study

    African Journals Online (AJOL)

    Elton

    particularly in patients who commence ART with low CD4 counts and established opportunistic infections. IRIS results from a pathological inflammatory response to pre-existing infective, host or other antigens, alive or dead, causing clinical deterioration in HIV-infected patients after initiating ART.1 A case definition for IRIS ...

  20. CASE STUDY

    African Journals Online (AJOL)

    2010-09-01

    Sep 1, 2010 ... of the two diseases surgery can be successful, recovery can be similar to that .... lymphocytes predominated in 68% of cases, and that there was an .... using ferritin is the fact that it acts as an acute-phase reactant and will be ...

  1. Methodology to characterize a residential building stock using a bottom-up approach: a case study applied to Belgium

    Directory of Open Access Journals (Sweden)

    Samuel Gendebien

    2014-06-01

    Full Text Available In the last ten years, the development and implementation of measures to mitigate climate change have become of major importance. In Europe, the residential sector accounts for 27% of the final energy consumption [1], and therefore contributes significantly to CO2 emissions. Roadmaps towards energy-efficient buildings have been proposed [2]. In such a context, the detailed characterization of residential building stocks in terms of age, type of construction, insulation level, energy vector, and of evolution prospects appears to be a useful contribution to the assessment of the impact of implementation of energy policies. In this work, a methodology to develop a tree-structure characterizing a residential building stock is presented in the frame of a bottom-up approach that aims to model and simulate domestic energy use. The methodology is applied to the Belgian case for the current situation and up to 2030 horizon. The potential applications of the developed tool are outlined.

  2. Case Study: Testing with Case Studies

    Science.gov (United States)

    Herreid, Clyde Freeman

    2015-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue discusses using case studies to test for knowledge or lessons learned.

  3. Angiofibroma of soft tissue: clinicopathologic study of 2 cases of a recently characterized benign soft tissue tumor.

    Science.gov (United States)

    Zhao, Ming; Sun, Ke; Li, Changshui; Zheng, Jiangjiang; Yu, Jingjing; Jin, Jie; Xia, Wenping

    2013-01-01

    Angiofibroma of soft tissue is a very recently characterized, histologically distinctive benign mesenchymal neoplasm of unknown cellular origin composed of 2 principal components, the spindle cell component and very prominent stromal vasculatures. It usually occurs in middle-aged adults, with a female predominance. Herein, we describe the clinical and pathologic details of 2 other examples of this benign tumor. Both patients were middle-aged male and presented with a slow-growing, painless mass located in the deep-seated soft tissue of thigh and left posterior neck region, respectively. Grossly, both tumors were well-demarcated, partial encapsulated of a grayish-white color with firm consistence. Histologically, one case showed morphology otherwise identical to those have been described before, whereas the other case showed in areas being more cellular than most examples of this subtype tumor had, with the lesional cells frequently exhibiting short fascicular, vaguely storiform and occasionally swirling arrangements, which posed a challenging differential diagnosis. Immunostains performed on both tumors did not confirm any specific cell differentiation with lesional cells only reactive for vimentin and focally desmin and negative for all the other markers tested. This report serves to broaden the morphologic spectrum of angiofibroma of soft tumor. Awareness of this tumor is important to prevent misdiagnosis as other more aggressive soft tissue tumor.

  4. Integrated use of surface geophysical methods for site characterization — A case study in North Kingstown, Rhode Island

    Science.gov (United States)

    Johnson, Carole D.; Lane, John W.; Brandon, William C.; Williams, Christine A.P.; White, Eric A.

    2010-01-01

    A suite of complementary, non‐invasive surface geophysical methods was used to assess their utility for site characterization in a pilot investigation at a former defense site in North Kingstown, Rhode Island. The methods included frequency‐domain electromagnetics (FDEM), ground‐penetrating radar (GPR), electrical resistivity tomography (ERT), and multi‐channel analysis of surface‐wave (MASW) seismic. The results of each method were compared to each other and to drive‐point data from the site. FDEM was used as a reconnaissance method to assess buried utilities and anthropogenic structures; to identify near‐surface changes in water chemistry related to conductive leachate from road‐salt storage; and to investigate a resistive signature possibly caused by groundwater discharge. Shallow anomalies observed in the GPR and ERT data were caused by near‐surface infrastructure and were consistent with anomalies observed in the FDEM data. Several parabolic reflectors were observed in the upper part of the GPR profiles, and a fairly continuous reflector that was interpreted as bedrock could be traced across the lower part of the profiles. MASW seismic data showed a sharp break in shear wave velocity at depth, which was interpreted as the overburden/bedrock interface. The MASW profile indicates the presence of a trough in the bedrock surface in the same location where the ERT data indicate lateral variations in resistivity. Depths to bedrock interpreted from the ERT, MASW, and GPR profiles were similar and consistent with the depths of refusal identified in the direct‐push wells. The interpretations of data collected using the individual methods yielded non‐unique solutions with considerable uncertainty. Integrated interpretation of the electrical, electromagnetic, and seismic geophysical profiles produced a more consistent and unique estimation of depth to bedrock that is consistent with ground‐truth data at the site. This test case shows that using

  5. Health Risk Assessment for Uranium in Groundwater - An Integrated Case Study Based on Hydrogeological Characterization and Dose Calculation

    Science.gov (United States)

    Franklin, M. R.; Veiga, L. H.; Py, D. A., Jr.; Fernandes, H. M.

    2010-12-01

    The uranium mining and milling facilities of Caetité (URA) is the only active uranium production center in Brazil. Operations take place at a very sensitive semi-arid region in the country where water resources are very scarce. Therefore, any contamination of the existing water bodies may trigger critical consequences to local communities because their sustainability is closely related to the availability of the groundwater resources. Due to the existence of several uranium anomalies in the region, groundwater can present radionuclide concentrations above the world average. The radiological risk associated to the ingestion of these waters have been questioned by members of the local communities, NGO’s and even regulatory bodies that suspected that the observed levels of radionuclide concentrations (specially Unat) could be related to the uranium mining and milling operations. Regardless the origin of these concentrations the fear that undesired health effects were taking place (e.g. increase in cancer incidence) remain despite the fact that no evidence - based on epidemiological studies - is available. This paper intends to present the connections between the local hydrogeology and the radiological characterization of groundwater in the neighboring areas of the uranium production center to understand the implications to the human health risk due to the ingestion of groundwater. The risk assessment was performed, taking into account the radiological and the toxicological risks. Samples from 12 wells have been collected and determinations of Unat, Thnat, 226Ra, 228Ra and 210Pb were performed. The radiation-related risks were estimated for adults and children by the calculation of the annual effective doses. The potential non-carcinogenic effects due to the ingestion of uranium were evaluated by the estimation of the hazard index (HI). Monte Carlo simulations were used to calculate the uncertainty associated with these estimates, i.e. the 95% confidence interval

  6. HYDROGEOLOGIC CASE STUDIES (DENVER PRESENTATION)

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  7. HYDROGEOLOGIC CASE STUDIES (CHICAGO, IL)

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  8. Hydrogeologic Case Studies (Seattle, WA)

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  9. CASE STUDY CRITIQUE; UPPER CLINCH CASE STUDY

    Science.gov (United States)

    Case study critique: Upper Clinch case study (from Research on Methods for Integrating Ecological Economics and Ecological Risk Assessment: A Trade-off Weighted Index Approach to Integrating Economics and Ecological Risk Assessment). This critique answers the questions: 1) does ...

  10. A Novel Multi-Approach Protocol for the Characterization of Occupational Exposure to Organic Dust-Swine Production Case Study.

    Science.gov (United States)

    Viegas, Carla; Faria, Tiago; Monteiro, Ana; Caetano, Liliana Aranha; Carolino, Elisabete; Quintal Gomes, Anita; Viegas, Susana

    2017-12-27

    Swine production has been associated with health risks and workers' symptoms. In Portugal, as in other countries, large-scale swine production involves several activities in the swine environment that require direct intervention, increasing workers' exposure to organic dust. This study describes an updated protocol for the assessment of occupational exposure to organic dust, to unveil an accurate scenario regarding occupational and environmental risks for workers' health. The particle size distribution was characterized regarding mass concentration in five different size ranges (PM0.5, PM1, PM2.5, PM5, PM10). Bioburden was assessed, by both active and passive sampling methods, in air, on surfaces, floor covering and feed samples, and analyzed through culture based-methods and qPCR. Smaller size range particles exhibited the highest counts, with indoor particles showing higher particle counts and mass concentration than outdoor particles. The limit values suggested for total bacteria load were surpassed in 35.7% (10 out of 28) of samples and for fungi in 65.5% (19 out of 29) of samples. Among Aspergillus genera, section Circumdati was the most prevalent (55%) on malt extract agar (MEA) and Versicolores the most identified (50%) on dichloran glycerol (DG18). The results document a wide characterization of occupational exposure to organic dust on swine farms, being useful for policies and stakeholders to act to improve workers' safety. The methods of sampling and analysis employed were the most suitable considering the purpose of the study and should be adopted as a protocol to be followed in future exposure assessments in this occupational environment.

  11. A Novel Multi-Approach Protocol for the Characterization of Occupational Exposure to Organic Dust—Swine Production Case Study

    Directory of Open Access Journals (Sweden)

    Carla Viegas

    2017-12-01

    Full Text Available Swine production has been associated with health risks and workers’ symptoms. In Portugal, as in other countries, large-scale swine production involves several activities in the swine environment that require direct intervention, increasing workers’ exposure to organic dust. This study describes an updated protocol for the assessment of occupational exposure to organic dust, to unveil an accurate scenario regarding occupational and environmental risks for workers’ health. The particle size distribution was characterized regarding mass concentration in five different size ranges (PM0.5, PM1, PM2.5, PM5, PM10. Bioburden was assessed, by both active and passive sampling methods, in air, on surfaces, floor covering and feed samples, and analyzed through culture based-methods and qPCR. Smaller size range particles exhibited the highest counts, with indoor particles showing higher particle counts and mass concentration than outdoor particles. The limit values suggested for total bacteria load were surpassed in 35.7% (10 out of 28 of samples and for fungi in 65.5% (19 out of 29 of samples. Among Aspergillus genera, section Circumdati was the most prevalent (55% on malt extract agar (MEA and Versicolores the most identified (50% on dichloran glycerol (DG18. The results document a wide characterization of occupational exposure to organic dust on swine farms, being useful for policies and stakeholders to act to improve workers’ safety. The methods of sampling and analysis employed were the most suitable considering the purpose of the study and should be adopted as a protocol to be followed in future exposure assessments in this occupational environment.

  12. Characterization of Composite Fan Case Resins

    Science.gov (United States)

    Dvoracek, Charlene M.

    2004-01-01

    The majority of commercial turbine engines that power today s aircraft use a large fan driven by the engine core to generate thrust which dramatically increases the engine s efficiency. However, if one of these fan blades fails during flight, it becomes high energy shrapnel, potentially impacting the engine or puncturing the aircraft itself and thus risking the lives of passengers. To solve this problem, the fan case must be capable of containing a fan blade should it break off during flight. Currently, all commercial fan cases are made of either just a thick metal barrier or a thinner metal wall surrounded by Kevlar-an ultra strong fiber that elastically catches the blade. My summer 2004 project was to characterize the resins for a composite fan case that will be lighter and more efficient than the current metal. The composite fan case is created by braiding carbon fibers and injecting a polymer resin into the braid. The resin holds the fibers together, so at first using the strongest polymer appears to logically lead to the strongest fan case. Unfortunately, the stronger polymers are too viscous when melted. This makes the manufacturing process more difficult because the polymer does not flow as freely through the braid, and the final product is less dense. With all of this in mind, it is important to remember that the strength of the polymer is still imperative; the case must still contain blades with high impact energy. The research identified which polymer had the right balance of properties, including ease of fabrication, toughness, and ability to transfer the load to the carbon fibers. Resin deformation was studied to better understand the composite response during high speed impact. My role in this research was the testing of polymers using dynamic mechanical analysis and tensile, compression, and torsion testing. Dynamic mechanical analysis examines the response of materials under cyclic loading. Two techniques were used for dynamic mechanical analysis

  13. Characterization of the relative importance of human- and infrastructure-associated bacteria in grey water: a case study.

    Science.gov (United States)

    Keely, S P; Brinkman, N E; Zimmerman, B D; Wendell, D; Ekeren, K M; De Long, S K; Sharvelle, S; Garland, J L

    2015-07-01

    Development of efficacious grey water (GW) treatment systems would benefit from detailed knowledge of the bacterial composition of GW. Thus, the aim of this study was to characterize the bacterial composition from (i) various points throughout a GW recycling system that collects shower and sink handwash (SH) water into an equalization tank (ET) prior to treatment and (ii) laundry (LA) water effluent of a commercial-scale washer. Bacterial composition was analysed by high-throughput pyrosequencing of the 16S rRNA gene. LA was dominated by skin-associated bacteria, with Corynebacterium, Staphylococcus, Micrococcus, Propionibacterium and Lactobacillus collectively accounting for nearly 50% of the total sequences. SH contained a more evenly distributed community than LA, with some overlap (e.g. Propionibacterium), but also contained distinct genera common to wastewater infrastructure (e.g. Zoogloea). The ET contained many of these same wastewater infrastructure-associated bacteria, but was dominated by genera adapted for anaerobic conditions. The data indicate that a relatively consistent set of skin-associated genera are the dominant human-associated bacteria in GW, but infrastructure-associated bacteria from the GW collection system and ET used for transient storage will be the most common bacteria entering GW treatment and reuse systems. This study is the first to use high-throughput sequencing to identify the bacterial composition of various GW sources. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.

  14. Characterizing the Severe Turbulence Environments Associated With Commercial Aviation Accidents. Part 1; 44 Case Study Synoptic Observational Analyses

    Science.gov (United States)

    Kaplan, Michael L.; Huffman, Allan W.; Lux, Kevin M.; Charney, Joseph J.; Riordan, Allan J.; Lin, Yuh-Lang; Proctor, Fred H. (Technical Monitor)

    2002-01-01

    A 44 case study analysis of the large-scale atmospheric structure associated with development of accident-producing aircraft turbulence is described. Categorization is a function of the accident location, altitude, time of year, time of day, and the turbulence category, which classifies disturbances. National Centers for Environmental Prediction Reanalyses data sets and satellite imagery are employed to diagnose synoptic scale predictor fields associated with the large-scale environment preceding severe turbulence. These analyses indicate a predominance of severe accident-producing turbulence within the entrance region of a jet stream at the synoptic scale. Typically, a flow curvature region is just upstream within the jet entrance region, convection is within 100 km of the accident, vertical motion is upward, absolute vorticity is low, vertical wind shear is increasing, and horizontal cold advection is substantial. The most consistent predictor is upstream flow curvature and nearby convection is the second most frequent predictor.

  15. Characterizing and modeling an electoral campaign in the context of Twitter: 2011 Spanish Presidential election as a case study.

    Science.gov (United States)

    Borondo, J; Morales, A J; Losada, J C; Benito, R M

    2012-06-01

    Transmitting messages in the most efficient way as possible has always been one of politicians' main concerns during electoral processes. Due to the rapidly growing number of users, online social networks have become ideal platforms for politicians to interact with their potential voters. Exploiting the available potential of these tools to maximize their influence over voters is one of politicians' actual challenges. To step in this direction, we have analyzed the user activity in the online social network Twitter, during the 2011 Spanish Presidential electoral process, and found that such activity is correlated with the election results. We introduce a new measure to study political sentiment in Twitter, which we call the relative support. We have also characterized user behavior by analyzing the structural and dynamical patterns of the complex networks emergent from the mention and retweet networks. Our results suggest that the collective attention is driven by a very small fraction of users. Furthermore, we have analyzed the interactions taking place among politicians, observing a lack of debate. Finally, we develop a network growth model to reproduce the interactions taking place among politicians.

  16. Geochemical characterization of supraglacial debris via in situ and optical remote sensing methods: a case study in Khumbu Himalaya, Nepal

    Directory of Open Access Journals (Sweden)

    K. A. Casey

    2012-01-01

    Full Text Available Surface glacier debris samples and field spectra were collected from the ablation zones of Nepal Himalaya Ngozumpa and Khumbu glaciers in November and December 2009. Geochemical and mineral compositions of supraglacial debris were determined by X-ray diffraction and X-ray fluorescence spectroscopy. This composition data was used as ground truth in evaluating field spectra and satellite supraglacial debris composition and mapping methods. Satellite remote sensing methods for characterizing glacial surface debris include visible to thermal infrared hyper- and multispectral reflectance and emission signature identification, semi-quantitative mineral abundance indicies and spectral image composites. Satellite derived supraglacial debris mineral maps displayed the predominance of layered silicates, hydroxyl-bearing and calcite minerals on Khumbu Himalayan glaciers. Supraglacial mineral maps compared with satellite thermal data revealed correlations between glacier surface composition and glacier surface temperature. Glacier velocity displacement fields and shortwave, thermal infrared false color composites indicated the magnitude of mass flux at glacier confluences. The supraglacial debris mapping methods presented in this study can be used on a broader scale to improve, supplement and potentially reduce errors associated with glacier debris radiative property, composition, areal extent and mass flux quantifications.

  17. Characterizing and modeling an electoral campaign in the context of Twitter: 2011 Spanish Presidential election as a case study

    Science.gov (United States)

    Borondo, J.; Morales, A. J.; Losada, J. C.; Benito, R. M.

    2012-06-01

    Transmitting messages in the most efficient way as possible has always been one of politicians' main concerns during electoral processes. Due to the rapidly growing number of users, online social networks have become ideal platforms for politicians to interact with their potential voters. Exploiting the available potential of these tools to maximize their influence over voters is one of politicians' actual challenges. To step in this direction, we have analyzed the user activity in the online social network Twitter, during the 2011 Spanish Presidential electoral process, and found that such activity is correlated with the election results. We introduce a new measure to study political sentiment in Twitter, which we call the relative support. We have also characterized user behavior by analyzing the structural and dynamical patterns of the complex networks emergent from the mention and retweet networks. Our results suggest that the collective attention is driven by a very small fraction of users. Furthermore, we have analyzed the interactions taking place among politicians, observing a lack of debate. Finally, we develop a network growth model to reproduce the interactions taking place among politicians.

  18. Chemical characterization of particulate air pollutants Case studies on indoor air quality, cultural heritage and the marine environment

    Science.gov (United States)

    Horemans, Benjamin

    When attempting to discuss the effects of airborne particulate matter (PM), it is important to address both physical and chemical aspects of this pollutant. This work reports on the results of three separate case studies, each approaching a specific problem of air pollution by evaluating the chemical composition of PM. 1. In the US and Europe, office workers often complain about work-related health symptoms. These symptoms are collectively referred as the 'sick building syndrome'. This work could be considered as one of the largest data collections on particulate pollutants in Belgian offices. It helps to understand the sources as well as the behavior and fate of PM at our workplace environments. Especially the chemical information on PM makes the results unique, since it enables a better evaluation of the health risks connected to office dust. 2. The Alhambra and Generalife bring every year more than 3 million people to Granada in Southern Spain. Recently, the increasing urbanization of Granada and the immense pressure of mass tourism form a threat for this heritage. Despite the fact that atmospheric pollutants are known to he potentially aggressive for our cultural patrimony. this case study is the first to assess the effects of environmental aerosols on the Alhambra monument. The results of this study could help decision-makers at the Alhambra and the city of Granada with the formulation of preventive conservation measures. They show how local vehicular traffic is the main source for atmospheric pollution in and around the Alhambra monument. Targeted strategies are necessary in order to maximally preserve these monuments and their UNESCO world cultural heritage label. 3. Excessive input of nitrogen-containing atmospheric nutrients via dry and wet deposition can cause entrophication of marine regions, which is also a common, seasonal phenomenon along the coasts of the North Sea. This study is the first to give a complete quantitative description of the

  19. Improved Method for Preparation of Amidoxime Modified Poly(acrylonitrile-co-acrylic acid: Characterizations and Adsorption Case Study

    Directory of Open Access Journals (Sweden)

    Nur Amirah Mohd Zahri

    2015-07-01

    Full Text Available Redox polymerization of poly(acrylonitrile-co-acrylic acid (poly(AN-co-AA is performed at 40 °C under N2 gas by varying the ratio of acrylonitrile (AN and acrylic acid (AA in the feed. The yield production of poly(acrylonitrile (PAN is 73% and poly(AN-co-AA with a feed ratio of 93:7 is the highest yield (72%. The PAN and poly(AN-co-AA are further chemically modify with hydroxylamine hydrochloride. The FTIR spectroscopy is used to confirm the copolymerization of poly(AN-co-AA and chemical modification of poly(AN-co-AA. Elemental microanalysis shows that the overall trend percentage of carbon, hydrogen, and nitrogen for all feed ratios are slightly decreasing as the feed ratio of AA is increasing except for poly(AN-co-AA 93:7. The SEM images shows that spherical diameter of poly(AN-co-AA is smaller compared to the PAN and amidoxime (AO modified poly(AN-co-AA. The TGA (thermogravimetric analysis analysis reveals that the poly(AN-co-AA degrades at lower temperatures compared to the PAN but higher than AO modified poly(AN-co-AA. The case study adsorption test showed that the AO modified poly(AN-co-AA 93:7 had the highest percentage removal of Cd2+ and Pb2+.

  20. Characterization of the multi-component driving land subsidence using Persistent Scatterer Interferometry technique: the Ravenna case of study (Italy)

    Science.gov (United States)

    Bonì, Roberta; Fiaschi, Simone; Calcaterra, Domenico; Di Martire, Diego; Ibrahim, Ahmed; Meisina, Claudia; Perini, Luisa; Ramondini, Massimo; Tessitore, Serena; Floris, Mario

    2015-04-01

    Land subsidence represents a kind of hazard, which affects an increasing number of worldwide regions, densely populated, causing damage to the environment and infrastructures. Settlements can be related to multiple processes both natural and anthropic (i.e. vadose zone processes, soil consolidation, aquifer compaction, solid and fluid extraction and load-induced compaction) which take place at different spatio-temporal scale. Over the last decades, advanced subsidence studies exploited Synthetic-Aperture Radar (SAR) data, a recent remote sensing tool, to investigate land subsidence phenomena around the world. In particular, Persistent Scatterer Interferometry (PSI) technique, allowing a quantitative estimation at high resolution of the surface deformations, has already been successfully applied to monitor the phenomenon evolution; PSI measurements represent the cumulative displacement, deriving from the contribution of natural and anthropic components, both superficial and deep. The overlapping of several causative factors makes more difficult to accurately interpret the resulting deformations; therefore, it is essential to implement a suitable methodology to distinguish the shallow and deep components of motion. The aim of our research is to introduce a PSI-based approach not only to monitoring but also to understand the land subsidence mechanism, in order to disentangle the natural and anthropic components of motion. The methodology consists of three main phases: 1) Post-processing elaborations (i.e. interpolation of the cumulated displacements and isokinetics map implementation); 2) Characterization of the subsidence areas (i.e. subsidence pattern recognition by means of automatic time series classification); 3) Mechanisms recognition (i.e. identification of the predisposing and triggering factors and comparison with lito-technical model of subsoil, and with earth measurements). In this work, the methodology has been applied to the Ravenna area, Italy, using

  1. Project management case studies

    CERN Document Server

    Kerzner, Harold R

    2013-01-01

    A new edition of the most popular book of project management case studies, expanded to include more than 100 cases plus a ""super case"" on the Iridium Project Case studies are an important part of project management education and training. This Fourth Edition of Harold Kerzner''s Project Management Case Studies features a number of new cases covering value measurement in project management. Also included is the well-received ""super case,"" which covers all aspects of project management and may be used as a capstone for a course. This new edition:Contains 100-plus case studies drawn from re

  2. Characterizing and modelling river channel migration rates at a regional scale: Case study of south-east France.

    Science.gov (United States)

    Alber, Adrien; Piégay, Hervé

    2017-11-01

    An increased awareness by river managers of the importance of river channel migration to sediment dynamics, habitat complexity and other ecosystem functions has led to an advance in the science and practice of identifying, protecting or restoring specific erodible corridors across which rivers are free to migrate. One current challenge is the application of these watershed-specific goals at the regional planning scales (e.g., the European Water Framework Directive). This study provides a GIS-based spatial analysis of the channel migration rates at the regional-scale. As a case study, 99 reaches were sampled in the French part of the Rhône Basin and nearby tributaries of the Mediterranean Sea (111,300 km 2 ). We explored the spatial correlation between the channel migration rate and a set of simple variables (e.g., watershed area, channel slope, stream power, active channel width). We found that the spatial variability of the channel migration rates was primary explained by the gross stream power (R 2  = 0.48) and more surprisingly by the active channel width scaled by the watershed area. The relationship between the absolute migration rate and the gross stream power is generally consistent with the published empirical models for freely meandering rivers, whereas it is less significant for the multi-thread reaches. The discussion focused on methodological constraints for a regional-scale modelling of the migration rates, and the interpretation of the empirical models. We hypothesize that the active channel width scaled by the watershed area is a surrogate for the sediment supply which may be a more critical factor than the bank resistance for explaining the regional-scale variability of the migration rates. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Using MODIS NDVI phenoclasses and phenoclusters to characterize wildlife habitat: Mexican spotted owl as a case study

    Science.gov (United States)

    Serra J. Hoagland; Paul Beier; Danny Lee

    2018-01-01

    Most uses of remotely sensed satellite data to characterize wildlife habitat have used metrics such as mean NDVI (Normalized Difference Vegetation Index) in a year or season. These simple metrics do not take advantage of the temporal patterns in NDVI within and across years and the spatial arrangement of cells with various temporal NDVI signatures. Here we use 13 years...

  4. Case Study Research Methodology

    Directory of Open Access Journals (Sweden)

    Mark Widdowson

    2011-01-01

    Full Text Available Commenting on the lack of case studies published in modern psychotherapy publications, the author reviews the strengths of case study methodology and responds to common criticisms, before providing a summary of types of case studies including clinical, experimental and naturalistic. Suggestions are included for developing systematic case studies and brief descriptions are given of a range of research resources relating to outcome and process measures. Examples of a pragmatic case study design and a hermeneutic single-case efficacy design are given and the paper concludes with some ethical considerations and an exhortation to the TA community to engage more widely in case study research.

  5. An integrated methodology for sub-surface fracture characterization using microseismic data: A case study at the NW Geysers

    Science.gov (United States)

    Aminzadeh, Fred; Tafti, Tayeb A.; Maity, Debotyam

    2013-04-01

    Geothermal and unconventional hydrocarbon reservoirs are often characterized by low permeability and porosity. So, they are difficult to produce and require stimulation techniques, such as thermal shear deactivation and hydraulic fracturing. Fractures provide porosity for fluid storage and permeability for fluid movement and play an important role in production from this kind of reservoirs. Hence, characterization of fractures has become a vitally important consideration in every aspect of exploration, development and production so as to provide additional energy resources for the world. During the injection or production of fluid, induced seismicity (micro-seismic events) can be caused by reactivated shears created fractures or the natural fractures in shear zones and faults. Monitoring these events can help visualize fracture growth during injection stimulation. Although the locations of microseismic events can be a useful characterization tool and have been used by many authors, we go beyond these locations to characterize fractures more reliably. Tomographic inversion, fuzzy clustering, and shear wave splitting are three methods that can be applied to microseismic data to obtain reliable characteristics about fractured areas. In this article, we show how each method can help us in the characterization process. In addition, we demonstrate how they can be integrated with each other or with other data for a more holistic approach. The knowledge gained might be used to optimize drilling targets or stimulation jobs to reduce costs and maximize production. Some of the concepts discussed in this paper are general in nature, and may be more applicable to unconventional hydrocarbon reservoirs than the metamorphic and igneous reservoir rocks at The Geysers geothermal field.

  6. Molecular characterization, biofilm analysis and experimental biofouling study of Fusarium isolates from recent cases of fungal keratitis in New York State

    Directory of Open Access Journals (Sweden)

    Samsonoff William A

    2007-01-01

    Full Text Available Abstract Background To characterize Fusarium isolates from recent cases of fungal keratitis in contact lens wearers, and to investigate fungal association with MoistureLoc solution. Methods We studied six fungal isolates from recent cases of keratitis in New York State. The isolates were characterized by nucleotide sequencing and phylogenetic analyses of multiple genes, and then typed using minisatellite and microsatellite probes. Experimental fungal biofilm formation was tested by standard methods. MoistureLoc solutions were tested in biofouling studies for their efficacy in elimination of Fusarium contamination. Results Fusarium solani – corneal ulcers (2 isolates, lens case (1 isolate, and F. oxysporum – corneal ulcer (1 isolate, eye (1 isolate, were recovered from five patients. An opened bottle of MoistureLoc solution provided by a patient also yielded F. solani. Two distinct genotypes of F. solani as well as of F. oxysporum were present in the isolated strains. Remarkably, F. solani strains from the lens case and lens solution in one instance were similar, based on phylogenetic analyses and molecular typing. The solution isolate of F. solani formed biofilm on contact lenses in control conditions, but not when co-incubated with MoistureLoc solution. Both freshly opened and 3-month old MoistureLoc solutions effectively killed F. solani and F. oxysporum, when fungal contamination was simulated under recommended lens treatment regimen (4-hr. However, simulation of inappropriate use (15 – 60 min led to the recovery of less than 1% of original inoculum of F. solani or F. oxysporum. Conclusion Temporary survival of F. solani and F. oxysporum in MoistureLoc suggested that improper lens cleaning regimen could be a possible contributing factor in recent infections.

  7. Characterizing floodplain evolution by joint analysis of SAR, GOES IR and local precipitation data: Case study of Rio Colorado, Bolivia

    Science.gov (United States)

    Koenders, R.; Oyen, A. M.; Weltje, G.; Sarna, K.; Donselaar, R.

    2013-12-01

    Radar (SAR) dataset. Our analysis shows that the response of the radar intensity to a major rainfall event consists of three phases. Just after a major rainfall event the radar intensity in inundated areas of the delta drops significantly with respect to its mean amplitude. As the time after inundation increases the radar signal is brighter than the long term average, after 10-20 days the region has generally reverted to its long term average radar intensity. This first phase corresponds well with the physical response of radar signals. When the delta is inundated the radar signal bounces away from the sensor, reducing the backscatter. The reason for the increased amount of backscatter during the second phase is less straightforward. Our fieldwork in the region suggests it correlates with an increase in roughness of the terrain possibly due to evaporation leaving a layer of salts. In the final phase, the return to the long term average is possibly achieved by aeolian erosion of the surface, reducing the roughness and thereby the amount of backscatter. In this study we demonstrate the feasibility of augmenting in-situ measurements with several types of spaceborne remote sensing data to monitor and characterize the evolution of the Rio Colorado floodplain in terms of spatial and temporal resolution, and report our results on the join analysis.

  8. Characterizing the hypersiliceous rocks of Belgium used in (pre-)history: a case study on sourcing sedimentary quartzites

    International Nuclear Information System (INIS)

    Veldeman, Isis; Baele, Jean-Marc; De Doncker, H W J A; Goemaere, Eric; Deceukelaire, Marleen; Dusar, Michiel

    2012-01-01

    Tracking raw material back to its extraction source is a crucial step for archaeologists when trying to deduce migration patterns and trade contacts in (pre-)history. Regarding stone artefacts, the main rock types encountered in the archaeological record of Belgium are hypersiliceous rocks. This is a newly introduced category of rock types comprising those rocks made of at least 90% silica. These are strongly silicified quartz sands or sedimentary quartzites, siliceous rocks of chemical and biochemical origin (e.g. flint), very pure metamorphic quartzites and siliceous volcanic rocks (e.g. obsidian). To be able to distinguish between different extraction sources, ongoing research was started to locate possible extraction sources of hypersiliceous rocks and to characterize rocks collected from these sources. Characterization of these hypersiliceous rocks is executed with the aid of optical polarizing microscopy, optical cold cathodoluminescence and scanning-electron microscopy combined with energy-dispersive x-ray spectrometry and with back-scatter electron imaging. In this paper, we focus on various sedimentary quartzites of Paleogene stratigraphical level. (paper)

  9. CHARACTERIZATION OF METAL GRADES IN A STOCKPILE OF AN IRON MINE (CASE STUDY- CHOGHART IRON MINE, IRAN

    Directory of Open Access Journals (Sweden)

    Francesco Tinti

    2018-01-01

    Full Text Available In any mining operation due to the cut-off grade (economic criteria, materials classify into the ore and waste. The material with grade equal to or higher than the cut-off grade is considered as ore and the material with grade less than the cut-off grade is transported as wastes to the waste dumps. However, because of increasing metal demand, depleting of in situ ore reserves and so the reduction of cut-off grades for many metals, the mentioned waste dumps were considered as valuable ore reserves named stockpiles. In this paper, multivariate geostatistics was used to estimate the iron grades of two stockpiles following the sequential of piling procedures from the main source - the ore deposit - to the piling field. One stockpile is characterized by phosphorous concentration ((P % > 0.6 %, while the other by iron concentration ((Fe %< 50%. Since economic and physical constraints made sampling physically and economically problematic, the grade distribution and variability were estimated on the basis of primary blast-hole data from the main ore body and the mine’s long-term planning policy. A geostatistical model was applied to the excavated part of the iron deposit and the stockpile, by reconstructing ore selection, haulage and piling method. Results were validated through spatial variability of iron and phosphorous concentrations by comparing grade variability (Fe and P with mining and pilling units. This methodology allows characterizing the iron grades within stockpiles without any extra sampling.

  10. Health risk characterization of chlorpyrifos using epidemiological dose-response data and probabilistic techniques: a case study with rice farmers in Vietnam.

    Science.gov (United States)

    Phung, Dung Tri; Connell, Des; Yu, Qiming; Chu, Cordia

    2013-09-01

    Various methods for risk characterization have been developed using probabilistic approaches. Data on Vietnamese farmers are available for the comparison of outcomes for risk characterization using different probabilistic methods. This article addresses the health risk characterization of chlorpyrifos using epidemiological dose-response data and probabilistic techniques obtained from a case study with rice farmers in Vietnam. Urine samples were collected from farmers and analyzed for trichloropyridinol (TCP), which was converted into absorbed daily dose of chlorpyrifos. Adverse health response doses due to chlorpyrifos exposure were collected from epidemiological studies to develop dose-adverse health response relationships. The health risk of chlorpyrifos was quantified using hazard quotient (HQ), Monte Carlo simulation (MCS), and overall risk probability (ORP) methods. With baseline (prior to pesticide spraying) and lifetime exposure levels (over a lifetime of pesticide spraying events), the HQ ranged from 0.06 to 7.1. The MCS method indicated less than 0.05% of the population would be affected while the ORP method indicated that less than 1.5% of the population would be adversely affected. With postapplication exposure levels, the HQ ranged from 1 to 32.5. The risk calculated by the MCS method was that 29% of the population would be affected, and the risk calculated by ORP method was 33%. The MCS and ORP methods have advantages in risk characterization due to use of the full distribution of data exposure as well as dose response, whereas HQ methods only used the exposure data distribution. These evaluations indicated that single-event spraying is likely to have adverse effects on Vietnamese rice farmers. © 2013 Society for Risk Analysis.

  11. Geophysical characterization of peatlands using crosshole GPR full-waveform inversion: Case study from a bog in northwestern Germany

    Science.gov (United States)

    Schmäck, J.; Klotzsche, A.; Van Der Kruk, J.; Vereecken, H.; Bechtold, M.

    2017-12-01

    The characterization of peatlands is of particular interest, since areas with peat soils represent global hotspots for the exchange of greenhouse gases. Their effect on global warming depends on several parameters, like mean annual water level and land use. Models of greenhouse gas emissions and carbon accumulation in peatlands can be improved by including small-scale soil properties that e.g. act as gas traps and periodically release gases to the atmosphere during ebullition events. Ground penetrating radar (GPR) is well suited to non- or minimal invasively characterize and improve our understanding of dynamic processes that take place in the critical zone. It uses high frequency electromagnetic waves to image and characterize the dielectric permittivity and electrical conductivity of the critical zone, which can be related to hydrogeological properties like porosity, soil water content, salinity and clay content. In the last decade, the full-waveform inversion of crosshole GPR data has proved to be a powerful tool to improve the image resolution compared to standard ray-based methods. This approach was successfully applied to several different aquifers and was able to provide decimeter-scale resolution images including small-scale high contrast layers that can be related to zones of high porosity, zones of preferential flow or clay lenses. The comparison to independently measured e.g. logging data proved the reliability of the method. Here, for the first time crosshole GPR full-waveform inversion is used to image three peatland plots with different land use that are part of the "Ahlen-Falkenberger Moor peat bog complex" in northwestern Germany. The full-waveform inversion of the acquired data returned higher resolution images than standard ray-based GPR methods, and, is able to improve our understanding of subsurface structures. The comparison of the different plots is expected to provide new insights into gas content and gas trapping structures across different

  12. Efficient biological process characterization by definitive-screening designs: the formaldehyde treatment of a therapeutic protein as a case study.

    Science.gov (United States)

    Erler, Axel; de Mas, Nuria; Ramsey, Philip; Henderson, Grant

    2013-03-01

    As part of the process-characterization campaign of a candidate vaccine product, a recently developed class of three-level designs-definitive-screening designs-was employed to select a quadratic model that describes the effect of six input process parameters, including protein concentration, formaldehyde-to-protein ratio, lysine concentration, reaction duration, pH, and reaction temperature, on a formylation protein-crosslinking reaction. This design requires only 17 experimental runs. The resulting model was then used to simulate 10,000 runs that account for the variability in the inputs expected on manufacturing scale. The extent of protein polymerization was predicted to be within specifications for all simulated runs, demonstrating the robustness of the unit operation for subsequent process validation and future commercial manufacturing.

  13. Risk Informed Safety Margin Characterization Case Study: Selection of Electrical Equipment To Be Subjected to Environmental Qualification

    Energy Technology Data Exchange (ETDEWEB)

    D. Blanchard; R. Youngblood

    2012-04-01

    In general, the margins-based safety case helps the decision-maker manage plant margins most effectively. It tells the plant decision-maker such things as what margin is present (at the plant level, at the functional level, at the barrier level, at the component level), and where margin is thin or perhaps just degrading. If the plant is safe, it tells the decision-maker why the plant is safe and where margin needs to be maintained, and perhaps where the plant can afford to relax.

  14. IMPACT 2002+, ReCiPe 2008 and ILCD’s recommended practice for characterization modelling in life cycle impact assessment: a case study-based comparison

    DEFF Research Database (Denmark)

    Owsianiak, Mikolaj; Laurent, Alexis; Bjørn, Anders

    2014-01-01

    Purpose The European Commission has launched a recommended set of characterization models and factors for application in life cycle impact assessment (LCIA). However, it is not known how this recommended practice, referred to as the ILCD 2009, performs relative to some of the most frequently used...... and ecosystems, all studied methodologies consistently identify the same window option as having the lowest and the highest environmental impact. This is mainly because few processes, associated with production of heat, dominate the total impacts, and there is a large difference in demand for heat between...... categories. The differences are somewhat smaller (within 1 order of magnitude) for the impact categories respiratory inorganics and photochemical ozone formation, and are within a factor of 3 for the remaining impact categories. The differences in impact scores in our case study are brought about...

  15. CHARACTERIZATION OF THE RISCK AREAS IN PETRÓPOLIS - A CASE STUDY OF THE LOPES TROVÃO COMMUNITY

    Directory of Open Access Journals (Sweden)

    Stella Peres Mendes

    2005-05-01

    Full Text Available Nature models the environment, provoking several physical processes as massmovements, erosion and sedimentation. Human action tends to intensify and accelerateenvironmental impacts, that become harmful to society, causing accidents that, depending onthe intensity, can cause tragedies.Mass movements are one of the processes that can cause more damages to the physicalenvironment and to society. According to Hamblin and Christiansen (1998, mass movementsinclude all types of collapses on the slopes. There are several types of mass movements, butlandslides are the most important ones, because it possess several condition factors and areevents that cause more problems to society.The increase of the urbanization Rio de Janeiro State causes the occupation of theslopes in an irregular and disordered way, resulting settlement, considerable environmentalimpacts on the controlling factors of the natural processes, causing other impacts, such asmass movements, that degrade not only the landscape, as well as people's life (Oliveira,2000.Some authors call the attention to the fact that the environmental degradation is, bydefinition, a social problem (Blaike and Brookfield, 1987. Some environmental processes, asleaching, erosion, mass movements and floods can happen with or without the humanintervention. In this way, characterizing physical processes, as environmental degradation, isto take into consideration social approaches that relate land use, or at least, with the potentialof several use types (Cunha and Guerra, 2003.

  16. Characterization and evaluation of agro-ecosystems on a farm scale a study case: The Paysandu farming center (Medellin. Colombia)

    International Nuclear Information System (INIS)

    Juan Camilo de los Rios Cardona; Andres Felipe Gallego Zapata; Leon Dario Velez Vargas; Agudelo Otalvaro, Jose Ignacio; Toro Restrepo, Luis Jairo; Lema Tapias, Alvaro de Jesus; Acevedo Agudelo, Luis Ignacio

    2004-01-01

    The state, condition, and tendencies of the agro-ecosystems (AE) of the Paysandu farming center of the Universidad Nacional de Colombia, sede Medellin were characterized and evaluated by means of parameterization and analysis of the various technological receptivity (RT, after the Spanish initials) and technological intensity (IT), based upon a methodological proposal of Velez and Gasto (1999), in terms of AE diversity and of the uses, management, and technological acceptance, techno-structural and hydro-structural endowment, potential productivity and services to the local, regional, and national society. The results showed that the greater part of the center (72%) has very low RT; which does not permit the establishment of mechanized advanced agro-technological management systems (SMA) however, 69.8% of the area is managed with SMA adequate for the restrictions imposed by the RT sixty-two percent of the area of the center, principally under pasture cover for dairy cattle production, is managed with advanced SMA. As a result of the interaction between RT and the SMA employed, six AE were identified, of which three, that represent 69.8% of the area (100.2 ha.), are managed with technologies adequate for their biophysical conditions or with technological receptivity (adequate IT), and the other three, that represent 28,57% of the are (43.1 ha.) ore managed with technologies that do not correspond to their RT conditions (tradition IT) which leads to a deterioration of their biophysical and ecological conditions

  17. Comprehensive genetic characterization of CLL: a study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping.

    Science.gov (United States)

    Haferlach, C; Dicker, F; Schnittger, S; Kern, W; Haferlach, T

    2007-12-01

    In CLL data from chromosome banding analysis (CBA) have been scarce due to the low proliferative activity of CLL cells in vitro. We improved the cultivation technique using an immunostimulatory CpG-oligonucleotide DSP30 and IL-2. A total of 506 CLL samples were analysed with CBA and interphase FISH using probes for the detection of trisomy 12, IgH rearrangements and deletions of 6q21, 11q22.3 (ATM), 13q14 (D13S25 and D13S319) and 17p13 (TP53). A total of 500 of 506 (98.8%) cases were successfully stimulated for metaphase generation and are subject to this study. Aberrations were detected in 415 of 500 (83.0%) cases by CBA and in 392 of 500 (78.4%) cases by FISH. CBA detected 832 abnormalities and FISH only 502. Therefore, CBA offers important information in addition to FISH. (1) CLL is characterized mainly by genomic imbalances and reciprocal translocations are rare. (2) A subgroup with complex aberrant karyotype (16.4%) is identified which is associated with an unmutated IgV(H) status and CD38 expression (P=0.034 and 0.02, respectively). (3) Additional abnormalities are detectable providing new biological insights into different CLL subclasses revealing a much more heterogeneous pattern of cytogenetic abnormalities as assumed so far based on FISH data only. Therefore, prospective clinical trials should evaluate the prognostic impact of newly available CBA data.

  18. 451 Case studies Cardiac

    African Journals Online (AJOL)

    Marinda

    Case Studies. 29 ... A case of a 26-year-old ASA I physical status male undergoing septoplasty had an abrupt ... myocardial infarction, severe hypertensive crisis, cerebral .... or no formal management is required in an ASA I patient.8 One.

  19. Case Study: Effect of Climatic Characterization on River Discharge in an Alpine-Prealpine Catchment of the Spanish Pyrenees Using the SWAT Model

    Directory of Open Access Journals (Sweden)

    Leticia Palazón

    2016-10-01

    Full Text Available The new challenges in assessment of water resources demand new approaches and tools, such as the use of hydrologic models, which could serve to assist managers in the prediction, planning and management of catchment water supplies in view of increased demand of water for irrigation and climatic change. Good characterization of the spatial patterns of climate variables is of paramount importance in hydrological modelling. This is especially so when modelling mountain environments which are characterized by strong altitudinal climate gradients. However, very often there is a poor distribution of climatic stations in these areas, which in many cases, results in under representation of high altitude areas with respect to climatic data. This results in the poor performance of the models. In the present study, the Soil and Water Assessment Tool (SWAT model was applied to the Barasona reservoir catchment in the Central Spanish Pyrenees in order to assess the influence of different climatic characterizations in the monthly river discharges. Four simulations with different input data were assessed, using only the available climate data (A1; the former plus one synthetic dataset at a higher altitude (B1; and both plus the altitudinal climate gradient (A2 and B2. The model’s performance was evaluated against the river discharges for the representative periods of 2003–2005 and 1994–1996 by means of commonly used statistical measures. The best results were obtained using the altitudinal climate gradient alone (scenario A2. This study provided insight into the importance of taking into account the sources and the spatial distribution of weather data in modelling water resources in mountainous catchments.

  20. Multiple approaches to characterize the microbial community in a thermophilic anaerobic digester running on swine manure: a case study.

    Science.gov (United States)

    Tuan, Nguyen Ngoc; Chang, Yi-Chia; Yu, Chang-Ping; Huang, Shir-Ly

    2014-01-01

    In this study, the first survey of microbial community in thermophilic anaerobic digester using swine manure as sole feedstock was performed by multiple approaches including denaturing gradient gel electrophoresis (DGGE), clone library and pyrosequencing techniques. The integrated analysis of 21 DGGE bands, 126 clones and 8506 pyrosequencing read sequences revealed that Clostridia from the phylum Firmicutes account for the most dominant Bacteria. In addition, our analysis also identified additional taxa that were missed by the previous researches, including members of the bacterial phyla Synergistetes, Planctomycetes, Armatimonadetes, Chloroflexi and Nitrospira which might also play a role in thermophilic anaerobic digester. Most archaeal 16S rRNA sequences could be assigned to the order Methanobacteriales instead of Methanomicrobiales comparing to previous studies. In addition, this study reported that the member of Methanothermobacter genus was firstly found in thermophilic anaerobic digester. Copyright © 2014 Elsevier GmbH. All rights reserved.

  1. Characterization of facial phenotypes of children with congenital hypopituitarism and their parents: a matched case-control study.

    Science.gov (United States)

    Manousaki, Despoina; Allanson, Judith; Wolf, Lior; Deal, Cheri

    2015-07-01

    Congenital Hypopituitarism (CH) has traditionally been associated with specific facial phenotypes subsumed under the term midface retrusion, based on cephalometric studies. In this study, we used a systematic anthropometric approach to facial morphology in 37 individuals with CH and their parents, primarily of French Canadian ancestry, and compared them to a control group of 78 French Canadian patients with well-controlled type 1 diabetes and their parents. We were able to demonstrate clear morphological differences, which were more prevalent in the affected group than in the control group. More specifically, we showed the presence of a shorter skull base width (P hypopituitarism and will provide further opportunities for data mining. © 2015 Wiley Periodicals, Inc.

  2. Multi-fractal characterization of bacterial swimming dynamics: a case study on real and simulated Serratia marcescens

    OpenAIRE

    Koorehdavoudi, Hana; Bogdan, Paul; Wei, Guopeng; Marculescu, Radu; Zhuang, Jiang; Carlsen, Rika Wright; Sitti, Metin

    2017-01-01

    To add to the current state of knowledge about bacterial swimming dynamics, in this paper, we study the fractal swimming dynamics of populations of Serratia marcescens bacteria both in vitro and in silico, while accounting for realistic conditions like volume exclusion, chemical interactions, obstacles and distribution of chemoattractant in the environment. While previous research has shown that bacterial motion is non-ergodic, we demonstrate that, besides the non-ergodicity, the bacterial sw...

  3. GPR impedance inversion for imaging and characterization of buried archaeological remains: A case study at Mudu city cite in Suzhou, China

    Science.gov (United States)

    Liu, Yu; Shi, Zhanjie; Wang, Bangbing; Yu, Tianxiang

    2018-01-01

    As a method with high resolution, GPR has been extensively used in archaeological surveys. However, conventional GPR profile can only provide limited geometry information, such as the shape or location of the interface, but can't give the distribution of physical properties which could help identify the historical remains more directly. A common way for GPR to map parameter distribution is the common-midpoint velocity analysis, but it provides limited resolution. Another research hotspot, the full-waveform inversion, is unstable and relatively dependent on the initial model. Coring method could give direct information in drilling site, while the accurate result is only limited in several boreholes. In this paper, we propose a new scheme to enhance imaging and characterization of archaeological targets by fusion of GPR and coring data. The scheme mainly involves the impedance inversion of conventional common-offset GPR data, which uses well log to compensate GPR data and finally obtains a high-resolution estimation of permittivity. The core analysis result also contributes to interpretation of the inversion result. To test this method, we did a case study at Mudu city site in Suzhou, China. The results provide clear images of the ancient city's moat and wall subsurface and improve the characterization of archaeological targets. It is shown that this method is effective and feasible for archaeological exploration.

  4. Corrosion Characterization in Nickel Plated 110 ksi Low Alloy Steel and Incoloy 925: An Experimental Case Study

    Science.gov (United States)

    Thomas, Kiran; Vincent, S.; Barbadikar, Dipika; Kumar, Shresh; Anwar, Rebin; Fernandes, Nevil

    2018-04-01

    Incoloy 925 is an age hardenable Nickel-Iron-Chromium alloy with the addition of Molybdenum, Copper, Titanium and Aluminium used in many applications in oil and gas industry. Nickel alloys are preferred mostly in corrosive environments where there is high concentration of H2S, CO2, chlorides and free Sulphur as sufficient nickel content provides protection against chloride-ion stress-corrosion cracking. But unfortunately, Nickel alloys are very expensive. Plating an alloy steel part with nickel would cost much lesser than a part make of nickel alloy for large quantities. A brief study will be carried out to compare the performance of nickel plated alloy steel with that of an Incoloy 925 part by conducting corrosion tests. Tests will be carried out using different coating thicknesses of Nickel on low alloy steel in 0.1 M NaCl solution and results will be verified. From the test results we can confirm that Nickel plated low alloy steel is found to exhibit fairly good corrosion in comparison with Incoloy 925 and thus can be an excellent candidate to replace Incoloy materials.

  5. Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study.

    Science.gov (United States)

    Cummins, Nathan W; Rizza, Stacey; Litzow, Mark R; Hua, Stephane; Lee, Guinevere Q; Einkauf, Kevin; Chun, Tae-Wook; Rhame, Frank; Baker, Jason V; Busch, Michael P; Chomont, Nicolas; Dean, Patrick G; Fromentin, Rémi; Haase, Ashley T; Hampton, Dylan; Keating, Sheila M; Lada, Steven M; Lee, Tzong-Hae; Natesampillai, Sekar; Richman, Douglas D; Schacker, Timothy W; Wietgrefe, Stephen; Yu, Xu G; Yao, Joseph D; Zeuli, John; Lichterfeld, Mathias; Badley, Andrew D

    2017-11-01

    Notwithstanding 1 documented case of HIV-1 cure following allogeneic stem cell transplantation (allo-SCT), several subsequent cases of allo-SCT in HIV-1 positive individuals have failed to cure HIV-1 infection. The aim of our study was to describe changes in the HIV reservoir in a single chronically HIV-infected patient on suppressive antiretroviral therapy who underwent allo-SCT for treatment of acute lymphoblastic leukemia. We prospectively collected peripheral blood mononuclear cells (PBMCs) by leukapheresis from a 55-year-old man with chronic HIV infection before and after allo-SCT to measure the size of the HIV-1 reservoir and characterize viral phylogeny and phenotypic changes in immune cells. At day 784 post-transplant, when HIV-1 was undetectable by multiple measures-including PCR measurements of both total and integrated HIV-1 DNA, replication-competent virus measurement by large cell input quantitative viral outgrowth assay, and in situ hybridization of colon tissue-the patient consented to an analytic treatment interruption (ATI) with frequent clinical monitoring. He remained aviremic off antiretroviral therapy until ATI day 288, when a low-level virus rebound of 60 HIV-1 copies/ml occurred, which increased to 1,640 HIV-1 copies/ml 5 days later, prompting reinitiation of ART. Rebounding plasma HIV-1 sequences were phylogenetically distinct from proviral HIV-1 DNA detected in circulating PBMCs before transplantation. The main limitations of this study are the insensitivity of reservoir measurements, and the fact that it describes a single case. allo-SCT led to a significant reduction in the size of the HIV-1 reservoir and a >9-month-long ART-free remission from HIV-1 replication. Phylogenetic analyses suggest that the origin of rebound virus was distinct from the viruses identified pre-transplant in the PBMCs.

  6. [Case and studies].

    Science.gov (United States)

    Schubert, András

    2015-11-15

    Case studies and case reports form an important and ever growing part of scientific and scholarly literature. The paper deals with the share and citation rate of these publication types on different fields of research. In general, evidence seems to support the opinion that an excessive number of such publications may negatively influence the impact factor of the journal. In the literature of scientometrics, case studies (at least the presence of the term "case study" in the titles of the papers) have a moderate share, but their citation rate is practically equal to that of other publication types.

  7. Structural characterization and discrimination of Chinese medicinal materials with multiple botanical origins based on metabolite profiling and chemometrics analysis: Clematidis Radix et Rhizoma as a case study.

    Science.gov (United States)

    Guo, Lin-Xiu; Li, Rui; Liu, Ke; Yang, Jie; Li, Hui-Jun; Li, Song-Lin; Liu, Jian-Qun; Liu, Li-Fang; Xin, Gui-Zhong

    2015-12-18

    Traditional Chinese medicines (TCMs)-based products are becoming more and more popular over the world. To ensure the safety and efficacy, authentication of Chinese medicinal materials has been an important issue, especially for that with multiple botanical origins (one-to-multiple). Taking Clematidis Radix et Rhizoma (CRR) as a case study, we herein developed an integrated platform based on metabolite profiling and chemometrics analysis to characterize, classify, and predict the "one-to-multiple" herbs. Firstly, the predominant constituents, triterpenoid saponins, in three Clematis CRR were rapid characterized by a novel UPLC-QTOF/MS-based strategy, and a total of 49 triterpenoid saponins were identified. Secondly, metabolite profiling was performed by UPLC-QTOF/MS, and 4623 variables were extracted and aligned as dataset. Thirdly, by using pattern recognition analysis, a clear separation of the three Clematis CRR was achieved as well as a total number of 28 variables were screened as the valuable variables for discrimination. By matching with identified saponins, these 28 variables were corresponding to 10 saponins which were identified as marker compounds. Fourthly, based on the relative intensity of the marker compounds-related variables, genetic algorithm optimized support vector machines (GA-SVM) was employed to predict the species of CRR samples. The obtained model showed excellent prediction performance with a prediction accuracy of 100%. Finally, a heatmap visualization was employed for clarifying the distribution of identified saponins, which could be useful for phytochemotaxonomy study of Clematis herbs. These results indicated that our proposed platform was a powerful tool for chemical profiling and discrimination of herbs with multiple botanical origins, providing promising perspectives in tracking the formulation processes of TCMs products. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Goiania incident case study

    International Nuclear Information System (INIS)

    Petterson, J.S.

    1988-06-01

    The reasons for wanting to document this case study and present the findings are simple. According to USDOE technical risk assessments (and our own initial work on the Hanford socioeconomic study), the likelihood of a major accident involving exposure to radioactive materials in the process of site characterization, construction, operation, and closure of a high-level waste repository is extremely remote. Most would agree, however, that there is a relatively high probability that a minor accident involving radiological contamination will occur sometime during the lifetime of the repository -- for example, during transport, at an MRS site or at the permanent site itself during repacking and deposition. Thus, one of the major concerns of the Yucca Mountain Socioeconomic Study is the potential impact of a relatively minor radiation-related accident. A large number of potential impact of a relatively minor radiation-related accident. A large number of potential accident scenarios have been under consideration (such as a transportation or other surface accident which results in a significant decline in tourism, the number of conventions, or the selection of Nevada as a retirement residence). The results of the work in Goiania make it clear, however, that such a significant shift in established social patterns and trends is not likely to occur as a direct outcome of a single nuclear-related accident (even, perhaps, a relatively major one), but rather, are likely to occur as a result of the enduring social interpretations of such an accident -- that is, as a result of the process of understanding, communicating, and socially sustaining a particular set of associations with respect to the initial incident

  9. Characterization of extractable soil organic matter pools from African Dark Earths (AfDE): A case study in historical biochar and organic waste amendments

    Science.gov (United States)

    Fujiu, Manna; Plante, Alain; Ohno, Tsutomu; Solomon, Dawit; Lehmann, Johannes; Fraser, James; Leach, Melissa; Fairhead, James

    2014-05-01

    Anthropogenic Dark Earths are soils generated through long-term human inputs of organic and pyrogenic materials. These soils were originally discovered in the Amazon, and have since been found in Australia and in this case in Africa. African Dark Earths (AfDE) are black, highly fertile and carbon-rich soils that were formed from the original highly-weathered infertile yellowish to red Oxisols and Ultisols through an extant but hitherto overlooked climate-smart sustainable soil management system that has long been an important feature of the indigenous West African agricultural repertoire. Studies have demonstrated that ADE soils in general have significantly different organic matter properties compared to adjacent non-DE soils, largely attributable to the presence of high concentrations of ash-derived carbon. Quantification and characterization of bulk soil organic matter of several (n=11) AfDE and non-AfDE pairs of surface (0-15 cm) soils using thermal analysis techniques (TG-DSC-EGA) confirmed substantial differences in SOM composition and the presence of pyrogenic C. Such pyrogenic organic matter is generally considered recalcitrant or relatively stable, but the goal of the current study was to characterize the presumably labile, more rapidly cycling, pools of C in AfDEs through the characterization of hot water- and pyrophosphate-extractable fractions, referred to as HWEOC and PyroC respectively. Extracts were analyzed for carbon content, as well as composition using fluorescence (EEM/PARAFAC) and high resolution mass spectrometry (FTICR-MS). The amount of extractable C as a proportion of total soil C was relatively low: less than ~0.8% for HWEOC and 2.8% for PyroC. The proportion of HWEOC did not differ (P = 0.18, paired t-test) between the AfDE and the non-AfDE soils, while the proportions of PyroC were significantly larger (P = 0.001) in the AfDE soils compared to the non-AfDE soils. Preliminary analysis of the EEM/PARAFAC data suggests that AfDE samples had

  10. Septic Systems Case Studies

    Science.gov (United States)

    A collection of septic systems case studies to help community planners, elected officials, health department staff, state officials, and interested citizens explore alternatives for managing their decentralized wastewater treatment systems.

  11. A Psychobiographical Case Study

    African Journals Online (AJOL)

    man, and cancer fighter. This psychobiographical case study entailed a psychosocial-historical ... does not draw more attention as a research method, as this approach has .... of the applied Levinsonian theory to the life of Jobs against the ...

  12. Characterization of individual ice residual particles by the single droplet freezing method: a case study in the Asian dust outflow region

    Science.gov (United States)

    Iwata, Ayumi; Matsuki, Atsushi

    2018-02-01

    pure or fresh calcite, Ca(NO3)2, and (NH4)2SO4 particles were more often found in the non-active fraction. In this study, we demonstrated the capability of the combined single droplet freezing method and thorough individual particle analysis to characterize the ice nucleation activity of atmospheric aerosols. We also found that dramatic changes in the particle mixing states during long-range transport had a complex effect on the ice nucleation activity of the host aerosol particles. A case study in the Asian dust outflow region highlighted the need to consider particle mixing states, which can dramatically influence ice nucleation activity.

  13. Characterization of individual ice residual particles by the single droplet freezing method: a case study in the Asian dust outflow region

    Directory of Open Access Journals (Sweden)

    A. Iwata

    2018-02-01

    dust particles. Also, relatively pure or fresh calcite, Ca(NO32, and (NH42SO4 particles were more often found in the non-active fraction. In this study, we demonstrated the capability of the combined single droplet freezing method and thorough individual particle analysis to characterize the ice nucleation activity of atmospheric aerosols. We also found that dramatic changes in the particle mixing states during long-range transport had a complex effect on the ice nucleation activity of the host aerosol particles. A case study in the Asian dust outflow region highlighted the need to consider particle mixing states, which can dramatically influence ice nucleation activity.

  14. Qualitative Case Study Guidelines

    Science.gov (United States)

    2013-11-01

    Introduction to Sociological Methods. 2nd ed. New York, McGraw-Hill 14. Denzin , N. K. and Lincoln , Y. S. (2011) The SAGE Handbook of Qualitative...The Art of Science. In: Denzin , N. K. and Lincoln , Y. S. (eds.) Handbook of Qualitative Research. Thousand Oaks, Sage 19. GAO (1990) Case Study...Rinehart & Winston 39. Stake, R. E. (1994) Case Studies. In: Denzin , N. K. and Lincoln , Y. S. (eds.) Handbook of Qualitative Research. Thousand Oaks, Sage

  15. An integrated approach of non-destructive tests for inspection and characterization of cultural heritage: case study of Monastery of Batalha, Portugal

    Science.gov (United States)

    Gonçalves, Luisa; Valença, Jonatas; Barraca, Nuno; Gaspar, Florindo

    2017-04-01

    analyzed giving emphasis to relevant limitations and solutions to optimize the surveys. Finally, a discussion is presented considering the complementarities and synergies between the different techniques according to the challenges presented in this case study. This work is a contribution to COST Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar" and has been supported by the COST Action TU1208 and the Fundação para a Ciência e a Tecnologia (FCT) under project grant UID/MULTI/00308/2013.

  16. Clinical-epidemiological characterization of leprosy cases with physical disabilities

    Directory of Open Access Journals (Sweden)

    Gleciane Costa de Sousa

    2017-01-01

    Full Text Available To characterize the clinical-epidemiological profile of cases of multibacillary leprosy, diagnosed with physical disabilities. Methods: this is a cross-sectional and retrospective study. The sample consisted of 276 cases of diagnosed leprosy. Results: leprosy mainly affects males, of brown skin color, low education and with a mean age of 51.96 years old (standard deviation, SD=20.33 years old. The Virchowian and dimorphic clinical forms are mainly responsible for the transmission of the disease and the development of physical disabilities. Decreased or lost sensation in hands and feet, trophic ulcers and traumatic injuries, as well as clawed hands were the physical disabilities prevalent in the study. Conclusion: the cases with physical disabilities are predominantly affected by multibacillary clinical forms, and they can be inferred in the maintenance of the transmission chain and the late detection of severe forms of leprosy.

  17. Objectivist case study research

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Fachner, Jörg

    2016-01-01

    be achieved through the use of objectivist case study research. The strength of the case study design is that it allows for uncovering or suggesting causal relationships in real-life settings through an intensive and rich collection of data. According to Hilliard (1993), the opposite applies for extensive......In order to comprehend the impact of music therapy or music therapy processes, a researcher might look for an approach where the topic under investigation can be understood within a broader context. This calls for a rich inclusion of data and consequently a limited number of participants and may...... designs, in which a small amount of data is gathered on a large number of subjects. With the richness of data, the intensive design is ―the primary pragmatic reason for engaging in single-case or small N research‖ (p. 374) and for working from an idiographic rather than a nomothetic perspective....

  18. Case Studies - Cervical Cancer

    Centers for Disease Control (CDC) Podcasts

    Dr. Alan Waxman, a professor of obstetrics and gynecology at the University of New Mexico and chair of the American College of Obstetricians and Gynecologists (ACOG) committee for the underserved, talks about several case studies for cervical cancer screening and management.

  19. Nuclear forensics case studies

    International Nuclear Information System (INIS)

    Fedchenko, Vitaly

    2016-01-01

    The objective of this presentation is to share three case studies from the Institute of Transuranium Elements (ITU) which describe the application of nuclear forensics to events where nuclear and other radioactive material was found to be out of regulatory control

  20. SCA12 case study

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 88; Issue 1. Utilizing linkage disequilibrium information from Indian Genome Variation Database for mapping mutations: SCA12 case study. Samira Bahl Ikhlak Ahmed The Indian Genome Variation Consortium Mitali Mukerji. Research Article Volume 88 Issue 1 April 2009 pp 55- ...

  1. national Case study

    African Journals Online (AJOL)

    This national case study reports on the development of a national network, ... system under the new policy), tends to be limited by content on problems and ... 20 credit programme; and within two Post Graduate Certificate of Education contexts, ...... descriptive with an issues focus (empirical) towards awareness production to.

  2. MRI case studies

    International Nuclear Information System (INIS)

    Huggett, S.; Barber, J.

    1989-01-01

    Three case studies are presented to show the value of magnetic resonance imaging used in conjunction with other imaging techniques. In each case MRI proved a vital diagnostic tool and superior to CT in showing firstly the haematoma in a patient with aphasia and right-sided weakness, secondly the size of the disc herniation in a patient with severe leg and ankle pains and thirdly the existence of a metastatic lesion in a patient with a previous history of breast cancer. 11 figs

  3. Innovations in Site Characterization Case Study: The Role of a Conceptual Site Model for Expedited Site Characterization Using the Triad Approach at the Poudre River Site, Fort Collins, Colorado

    Science.gov (United States)

    This case study examines how systematic planning, an evolving conceptual site model (CSM), dynamic work strategies, and real time measurement technologies can be used to unravel complex contaminant distribution patterns...

  4. Case study - Czechoslovakia

    International Nuclear Information System (INIS)

    Kovar, P.

    1986-01-01

    In the lecture Case Study - Czechoslovakia with the sub-title 'Unified System of Personnel Preparation for Nuclear Programme in Czechoslovakia' the actual status and the current experience of NPP personnel training and preparation in Czechoslovakia are introduced. The above mentioned training system is presented and demonstrated by the story of a proxy person who is going to become shift engineer in a nuclear power plant in Czechoslovakia. (orig./HP)

  5. Case Studies - Cervical Cancer

    Centers for Disease Control (CDC) Podcasts

    2010-10-15

    Dr. Alan Waxman, a professor of obstetrics and gynecology at the University of New Mexico and chair of the American College of Obstetricians and Gynecologists (ACOG) committee for the underserved, talks about several case studies for cervical cancer screening and management.  Created: 10/15/2010 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), Division of Cancer Prevention and Control (DCPC).   Date Released: 6/9/2010.

  6. Advantages of active love wave techniques in geophysical characterizations of seismographic station - Case studies in California and the central and eastern United States

    Science.gov (United States)

    Martin, Antony; Yong, Alan K.; Salomone, Larry A.

    2014-01-01

    Active-source Love waves, recorded by the multi-channel analysis of surface wave (MASLW) technique, were recently analyzed in two site characterization projects. Between 2010 and 2012, the 2009 American Recovery and Reinvestment Act (ARRA) funded GEOVision to conduct geophysical investigations at 191 seismographic stations in California and the Central Eastern U.S. (CEUS). The original project plan was to utilize active and passive Rayleigh wave-based techniques to obtain shear-wave velocity (VS) profiles to a minimum depth of 30 m and the time-averaged VS of the upper 30 meters (VS30). Early in this investigation it became clear that Rayleigh wave techniques, such as multi-channel analysis of surface waves (MASRW), were not suited for characterizing all sites. Shear-wave seismic refraction and MASLW techniques were therefore applied. In 2012, the Electric Power Research Institute funded characterization of 33 CEUS station sites. Based on experience from the ARRA investigation, both MASRW and MASLW data were acquired by GEOVision at 24 CEUS sites. At shallow rock sites, sites with steep velocity gradients, and, sites with a thin, low velocity, surficial soil layer overlying stiffer sediments, Love wave techniques generally were found to be easier to interpret, i.e., Love wave data typically yielded unambiguous fundamental mode dispersion curves and thus, reduce uncertainty in the resultant VS model. These types of velocity structure often excite dominant higher modes in Rayleigh wave data, but not in the Love wave data. It is possible to model Rayleigh wave data using multi- or effective-mode techniques; however, extraction of Rayleigh wave dispersion data was found to be difficult in many cases. These results imply that field procedures should include careful scrutiny of Rayleigh wave-based dispersion data in order to also collect Love wave data when warranted.

  7. Improving the characterization of fish assemblage structure through the use of multiple sampling methods: a case study in a subtropical tidal flat ecosystem.

    Science.gov (United States)

    Contente, Riguel Feltrin; Del Bianco Rossi-Wongtschowski, Carmen Lucia

    2017-06-01

    The use of multiple sampling gears is indispensible to obtain robust characterizations of fish assemblage structure in species-rich subtropical ecosystems. In this study, such a dependence was demonstrated by characterizing the structure of the high-tide fish assemblage in a subtropical tidal flat ecosystem (the Araçá Bay, southeastern Brazil) using eight different gears along five seasonal surveys and estimating the bay's fish species richness, combining these data with those from local tide pool fish surveys. The high-tide fish assemblage was spatially structured, contained five threatened species, and was dominated by persistent and large populations of Eucinostomus argenteus and of the fisheries species Mugil curema and Diapterus rhombeus that intensively use the bay throughout their life cycles. Large, small-bodied fish populations supported a regular use of the bay by piscivores. The autumn-winter peak in abundance of juvenile fishes caused a subsequent increase in piscivore abundance, and both events explained the bulk of the seasonal variability of the fish assemblage. The estimated richness revealed that the combination of sampling methods was enough for sampling the bulk of the local richness, and the bay may hold a surprisingly high richness compared to other costal ecosystem of the region. This faunal characterization, only viable using multiple gears, will be critical to support the implementation of a future study to monitor the impacts on local fish biodiversity of an imminent port expansion over the tidal flat.

  8. Case Study - Alpha

    Directory of Open Access Journals (Sweden)

    Stephen Leybourne

    2016-11-01

    Full Text Available This case study was developed from an actual scenario by Dr. Steve Leybourne of Boston University.  The case documents the historical evolution of an organization, and has been used successfully in courses dealing with organizational and cultural change, and the utilization of ‘soft skills’ in project-based management. This is a short case, ideal for classroom use and discussion.  The issues are easily accessible to students, and there is a single wide ranging question that allows for the inclusion of many issues surrounding strategic decision-making, and behavioural and cultural change. Alpha was one of the earlier companies in the USA to invest in large, edge-of-town superstores, with plentiful free vehicle parking, selling food and related household products. Alpha was created in the 1950s as a subsidiary of a major publicly quoted retail group.  It started business by opening a string of very large discount stores in converted industrial and warehouse premises in the south of the United States. In the early days shoppers were offered a limited range of very competitively priced products. When Alpha went public in 1981 it was the fourth largest food retailer in the US, selling an ever-widening range of food and non-food products.  Its success continued to be based on high volume, low margins and good value for money, under the slogan of ‘Alpha Price.’

  9. 2D resistivity imaging and magnetic survey for characterization of thermal springs: A case study of Gergedi thermal springs in the northwest of Wonji, Main Ethiopian Rift, Ethiopia

    Science.gov (United States)

    Abdulkadir, Yahya Ali; Eritro, Tigistu Haile

    2017-09-01

    Electrical resistivity imaging and magnetic surveys were carried out at Gergedi thermal springs, located in the Main Ethiopian Rift, to characterize the geothermal condition of the area. The area is geologically characterized by alluvial and lacustrine deposits, basaltic lava, ignimbrites, and rhyolites. The prominent structural feature in this part of the Main Ethiopian Rift, the SW -NE trending structures of the Wonji Fault Belt System, crosse over the study area. Three lines of imaging data and numerous magnetic data, encompassing the active thermal springs, were collected. Analysis of the geophysical data shows that the area is covered by low resistivity response regions at shallow depths which resulted from saline moisturized soil subsurface horizon. Relatively medium and high resistivity responses resulting from the weathered basalt, rhyolites, and ignimbrites are also mapped. Qualitative interpretation of the magnetic data shows the presence of structures that could act as pathways for heat and fluids manifesting as springs and also characterize the degree of thermal alteration of the area. Results from the investigations suggest that the Gergedi thermal springs area is controlled by fault systems oriented parallel and sub-parallel to the main tectonic lines of the Main Ethiopian Rift.

  10. NOx trade. Case studies

    International Nuclear Information System (INIS)

    Jantzen, J.

    2002-01-01

    Some of the questions with respect to the trade of nitrogen oxides that businesses in the Netherlands have to deal with are dealt with: should a business buy or sell rights for NOx emission; which measures must be taken to reduce NOx emission; how much must be invested; and how to deal with uncertainties with regard to prices. Simulations were carried out with the MOSES model to find the answers to those questions. Results of some case studies are presented, focusing on the chemical sector in the Netherlands. Finally, the financial (dis)advantages of NOx trade and the related uncertainties for a single enterprise are discussed [nl

  11. OBSESSIONS: CASE REPORT STUDY

    Directory of Open Access Journals (Sweden)

    Miloš Židanik

    2004-01-01

    Full Text Available Background. Obsessions are one of the most refractory psychiatric disorders. The therapeutic guidelines include a psychopharmacotherapy and the use of behavioural and supportive psychotherapy.Methods. This case report study presents a patient with a homicide obsessions at the forefront and narcissistic personality disorder in background. The use of analytical oriented psychotherapy, which helped to resolve axis-1 symptoms, is described.Conclusions. In the therapy of patients it is important to have the knowledge about the national therapeutic guidelines and critical distance toward them as well. Which therapy to use should be decided by the individual patient’s needs.

  12. Immunological characterization and transcription profiling of peripheral blood (PB monocytes in children with autism spectrum disorders (ASD and specific polysaccharide antibody deficiency (SPAD: case study

    Directory of Open Access Journals (Sweden)

    Jyonouchi Harumi

    2012-01-01

    Full Text Available Abstract Introduction There exists a small subset of children with autism spectrum disorders (ASD characterized by fluctuating behavioral symptoms and cognitive skills following immune insults. Some of these children also exhibit specific polysaccharide antibody deficiency (SPAD, resulting in frequent infection caused by encapsulated organisms, and they often require supplemental intravenous immunoglobulin (IVIG (ASD/SPAD. This study assessed whether these ASD/SPAD children have distinct immunological findings in comparison with ASD/non-SPAD or non-ASD/SPAD children. Case description We describe 8 ASD/SPAD children with worsening behavioral symptoms/cognitive skills that are triggered by immune insults. These ASD/SPAD children exhibited delayed type food allergy (5/8, treatment-resistant seizure disorders (4/8, and chronic gastrointestinal (GI symptoms (5/8 at high frequencies. Control subjects included ASD children without SPAD (N = 39, normal controls (N = 37, and non-ASD children with SPAD (N = 12. Discussion and Evaluation We assessed their innate and adaptive immune responses, by measuring the production of pro-inflammatory and counter-regulatory cytokines by peripheral blood mononuclear cells (PBMCs in responses to agonists of toll like receptors (TLR, stimuli of innate immunity, and T cell stimulants. Transcription profiling of PB monocytes was also assessed. ASD/SPAD PBMCs produced less proinflammatory cytokines with agonists of TLR7/8 (IL-6, IL-23, TLR2/6 (IL-6, TLR4 (IL-12p40, and without stimuli (IL-1ß, IL-6, and TNF-α than normal controls. In addition, cytokine production of ASD/SPAD PBMCs in response to T cell mitogens (IFN-γ, IL-17, and IL-12p40 and candida antigen (Ag (IL-10, IL-12p40 were less than normal controls. ASD/non-SPAD PBMDs revealed similar results as normal controls, while non-ASD/SPAD PBMCs revealed lower production of IL-6, IL-10 and IL-23 with a TLR4 agonist. Only common features observed between ASD/SPAD and non

  13. Characterization of industrial waste from a natural gas distribution company and management strategies: a case study of the East Azerbaijan Gas Company (Iran).

    Science.gov (United States)

    Taghipour, Hassan; Aslhashemi, Ahmad; Assadi, Mohammad; Khodaei, Firoz; Mardangahi, Baharak; Mosaferi, Mohammad; Roshani, Babak

    2012-10-01

    Although a fundamental prerequisite for the successful implementation of any waste management plan is the availability of sufficient and accurate data, there are few available studies regarding the characterization and management of gas distribution company waste (GDCW). This study aimed to characterize the industrial waste generated by the East Azerbaijan Gas Distribution Company (EAGDC) and to present environmental management strategies. The EAGDC serves 57 cities and 821 villages with a total population of more than 2.5 million as well as numerous industrial units. The methodology of this study was based on a checklist of data collected from each zone of the company, site visits (observation), and quantity and quality analysis according to the formal data available from different zones. The results indicate that more than 35 different kinds of industrial solid waste are generated in different industrial installations. The most important types of generated waste include empty barrels (including mercaptans, diesel fuel, deionized waters and oil), faulty gas meters and regulators, a variety of industrial oils, sleeves, filter elements and faulty pipes, valves and fittings. The results indicated that, currently, GDCW is generally handled and disposed of with domestic waste, deposited in companies' installation yards and stores or, sometimes, recycled through non-scientific approaches that can create health risks to the public and the environment, even though most of the GDCW was determined to be recyclable or reusable materials. This study concludes that gas distribution companies must pay more attention to source reduction, recycling and reusing of waste to preserve natural resources, landfill space and the environment.

  14. Petrographic characterization to build an accurate rock model using micro-CT: Case study on low-permeable to tight turbidite sandstone from Eocene Shahejie Formation.

    Science.gov (United States)

    Munawar, Muhammad Jawad; Lin, Chengyan; Cnudde, Veerle; Bultreys, Tom; Dong, Chunmei; Zhang, Xianguo; De Boever, Wesley; Zahid, Muhammad Aleem; Wu, Yuqi

    2018-03-26

    Pore scale flow simulations heavily depend on petrographic characterizing and modeling of reservoir rocks. Mineral phase segmentation and pore network modeling are crucial stages in micro-CT based rock modeling. The success of the pore network model (PNM) to predict petrophysical properties relies on image segmentation, image resolution and most importantly nature of rock (homogenous, complex or microporous). The pore network modeling has experienced extensive research and development during last decade, however the application of these models to a variety of naturally heterogenous reservoir rock is still a challenge. In this paper, four samples from a low permeable to tight sandstone reservoir were used to characterize their petrographic and petrophysical properties using high-resolution micro-CT imaging. The phase segmentation analysis from micro-CT images shows that 5-6% microporous regions are present in kaolinite rich sandstone (E3 and E4), while 1.7-1.8% are present in illite rich sandstone (E1 and E2). The pore system percolates without micropores in E1 and E2 while it does not percolate without micropores in E3 and E4. In E1 and E2, total MICP porosity is equal to the volume percent of macrospores determined from micro-CT images, which indicate that the macropores are well connected and microspores do not play any role in non-wetting fluid (mercury) displacement process. Whereas in E3 and E4 sandstones, the volume percent of micropores is far less (almost 50%) than the total MICP porosity which means that almost half of the pore space was not detected by the micro-CT scan. PNM behaved well in E1 and E2 where better agreement exists in PNM and MICP measurements. While E3 and E4 exhibit multiscale pore space which cannot be addressed with single scale PNM method, a multiscale approach is needed to characterize such complex rocks. This study provides helpful insights towards the application of existing micro-CT based petrographic characterization methodology

  15. Physical-Chemical Characterization of Solid Waste Generated in the Water Industry: Case Study of the Water Treatment Stations of the Metropolitan Region of Recife

    Directory of Open Access Journals (Sweden)

    Rosângela Gomes Tavares

    2017-12-01

    Full Text Available The objective of this research is to characterize the solid waste, commonly known as sludge, from the water treatment industry. Six main water treatment plants (Alto do Céu, Botafogo, Caixa d'água, Gurjaú, Suape and Tapacurá were selected from the Metropolitan Region of Recife, managed by Companhia Pernambucana de Saneamento. Nine samples were collected in the eleven month period in the discharge of the sludge from the decanters. These samples were characterized physico-chemically, based on the methodology of the Standard Methods for the Examination of Water and Wastewater (2012. The results indicated average humidity of 93%, average COD around 30 g/L and BOD of 4.5 g/L, indicating sludge of low biodegradability. The average values of total solids were 72 g/L, with 75% corresponding to fixed residues and 25% to volatiles. High concentrations of aluminum (1000 mg/L were observed, due to the use of aluminum sulphate as a coagulant, and iron, around 500 mg/L. This study assists the manager in the decision making of the sustainable management of the sludge, mainly in relation to the final disposal.

  16. Isotopic and hydrogeochemical characterization of high-altitude karst aquifers in complex geological settings. The Ordesa and Monte Perdido National Park (Northern Spain) case study

    Energy Technology Data Exchange (ETDEWEB)

    Lambán, L.J., E-mail: javier.lamban@igme.es [Geological Survey of Spain (IGME) (Spain); Jódar, J., E-mail: jorge.jodar@upc.edu [Department of Geotechnical Engineering and Geosciences, Technical University of Catalonia (UPC), Barcelona (Spain); Custodio, E., E-mail: emilio.custodio@upc.edu [Department of Geotechnical Engineering and Geosciences, Technical University of Catalonia (UPC), Barcelona (Spain); Soler, A., E-mail: albertsoler@ub.edu [Grup de Mineralogia Aplicada i Medi Ambient, Departament Cristal lografia Mineralogia i Dipòsits Minerals, Facultat de Geologia, Universitat de Barcelona (UB) (Spain); Sapriza, G., E-mail: g.sapriza@usask.ca [Global Institute for Water Security, National Hydrology Research Centre (Canada); Soto, R., E-mail: r.soto@igme.es [Geological Survey of Spain (IGME) (Spain)

    2015-02-15

    The Ordesa and Monte Perdido National Park, located in the Southern Pyrenees, constitutes the highest karst system in Western Europe. No previous studies regarding its geochemical and isotopic groundwater characterization are available in this area. This work presents the results of field and sampling campaigns carried out between July 2007 and September 2013. The groundwater presents high calcium bicarbonate contents due to the occurrence of upper Cretaceous and lower Paleocene–Eocene carbonate materials in the studied area. Other relevant processes include dissolution of anhydrite and/or gypsum and incongruent dissolution of Mg-limestone and dolomite. The water stable isotopes (δ{sup 18}O, δ{sup 2}H) show that the oceanic fronts from the Atlantic Ocean are responsible for the high levels of precipitation. In autumn, winter, and spring, a deuterium excess is found in the recharge water, which could be related to local atmospheric transport of low-altitude snow sublimation vapour and its later condensation on the snow surface at higher altitude, where recharge is mostly produced. The recharge zones are mainly between 2500 m and 3200 m a.s.l. The tritium content of the water suggests short groundwater transit times. The isotopic composition of dissolved sulphate points to the existence of regional fluxes mixed with local discharge in some of the springs. This work highlights the major role played by the altitude difference between the recharge and discharge zones in controlling the chemistry and the vertical variability of the isotopic composition in high-altitude karst aquifers. - Highlights: • Environmental tracers are essential to study complex alpine karst aquifers. • The long presence of snow controls the deuterium excess in groundwater. • Seasonal δD content in springs depends on gap between recharge and discharge points. • The first hydrogeological characterization of the Ordesa National Park is presented. • Sulphate content in springs comes

  17. Multidisciplinary approach for the characterization of landslides in volcanic areas - a case study from the Palma Sola-Chiconquiaco Mountain Range, Mexico

    Science.gov (United States)

    Wilde, Martina; Rodríguez Elizarrarás, Sergio R.; Morales Barrera, Wendy V.; Schwindt, Daniel; Bücker, Matthias; Flores Orozco, Adrián; García García, Emilio; Pita de la Paz, Carlos; Terhorst, Birgit

    2017-04-01

    The Palma Sola-Chiconquiaco mountain range, situated in the State of Veracruz, Mexico, is highly susceptible to landslides, which is evidenced by the high frequency of landslide events of different sizes. The study area is located near the Gulf of Mexico coastline in the eastern sector of the Trans Mexican Volcanic Belt. There, landslide triggers are intense rainfalls related to tropical storms and hurricanes. Steeper slopes are commonly affected by rockfalls, whereas moderate slopes, covered by massive slope deposits, are affected by shallow as well as deep seated landslides. Some of the landslides in the slope deposits reach dimensions of more than 1000 m in length and depths of over 30 m. The heterogeneous parent material as well as older slide masses hamper the detailed characterization of the involved materials. Therefore, in this study, a multidisciplinary approach is applied that integrates geomorphological, geological, and geophysical data. The aim is the reconstruction of process dynamics by analyzing the geomorphological situation and subsurface conditions before and after the event. The focus lies on the identification of past landslide areas, which represent areas with high susceptibility for the reactivation of old slide masses. Furthermore, the analysis of digital terrain models, generated before the landslide event, indicate initial movements like extension cracks, which are located close to the current scarp area. In order to characterize the subsurface of slide masses geophysical investigations are applied. The geophysical survey consists of a total of nine profiles covering relevant key features of the large affected area. Along these profiles, electrical resistivity tomography (ERT) and seismic refraction tomography (SRT) data were collected. Both, electrical and seismic images reveal a sharp contrast between relatively loose and dry material of the slide mass (high resistivities and low seismic velocities) and the former land surface that is

  18. Evaluation of the Pivot Profile©, a new method to characterize a large variety of a single product: Case study on honeys from around the world.

    Science.gov (United States)

    Deneulin, Pascale; Reverdy, Caroline; Rébénaque, Pierrick; Danthe, Eve; Mulhauser, Blaise

    2018-04-01

    Honey is a natural product with very diverse sensory attributes that are influenced by the flower source, the bee species, the geographic origin, the treatments and conditions during storage. This study aimed at describing 50 honeys from diverse flower sources in different continents and islands, stored under various conditions. Many articles have been published on the sensory characterization of honeys, thus a common list of attributes has been established, but it appeared to be poorly suited to describe a large number of honeys from around the world. This is why the novel and rapid sensory evaluation method, the Pivot Profile©, was tested, with the participation of 15 panelists during five sessions. The first objective was to obtain a sensory description of the 50 honeys that were tested. From 1152 distinct terms, a list of 29 sensory attributes was established and the attributes divided into three categories: color/texture (8 terms), aroma (16 terms), and taste (5 terms). At first, the honeys have been ranked according to their level of crystallization from fluid/liquid to viscous/hard. Then color was the second assessment factor of the variability. In terms of aroma, honeys from Africa were characterized by smoky, resin, caramel and dried fruit as opposed to floral and fruity, mainly for honeys from South America and Europe. Finally, the honeys were ranked according to their sweetness. The second objective of this study was to test the new sensory method, called Pivot Profile© which is used to describe a large number of products with interpretable results. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. FMCT verification: Case studies

    International Nuclear Information System (INIS)

    Hui Zhang

    2001-01-01

    Full text: How to manage the trade-off between the need for transparency and the concern about the disclosure of sensitive information would be a key issue during the negotiations of FMCT verification provision. This paper will explore the general concerns on FMCT verification; and demonstrate what verification measures might be applied to those reprocessing and enrichment plants. A primary goal of an FMCT will be to have the five declared nuclear weapon states and the three that operate unsafeguarded nuclear facilities become parties. One focus in negotiating the FMCT will be verification. Appropriate verification measures should be applied in each case. Most importantly, FMCT verification would focus, in the first instance, on these states' fissile material production facilities. After the FMCT enters into force, all these facilities should be declared. Some would continue operating to produce civil nuclear power or to produce fissile material for non- explosive military uses. The verification measures necessary for these operating facilities would be essentially IAEA safeguards, as currently being applied to non-nuclear weapon states under the NPT. However, some production facilities would be declared and shut down. Thus, one important task of the FMCT verifications will be to confirm the status of these closed facilities. As case studies, this paper will focus on the verification of those shutdown facilities. The FMCT verification system for former military facilities would have to differ in some ways from traditional IAEA safeguards. For example, there could be concerns about the potential loss of sensitive information at these facilities or at collocated facilities. Eventually, some safeguards measures such as environmental sampling might be seen as too intrusive. Thus, effective but less intrusive verification measures may be needed. Some sensitive nuclear facilities would be subject for the first time to international inspections, which could raise concerns

  20. Characterizing the influence of transportation infrastructure on Emergency Medical Services (EMS) in urban area-A case study of Seoul, South Korea.

    Science.gov (United States)

    Cho, Jungwoo; You, Myoungsoon; Yoon, Yoonjin

    2017-01-01

    In highly urbanized area where traffic condition fluctuates constantly, transportation infrastructure is one of the major contributing factors to Emergency Medical Service (EMS) availability and patient outcome. In this paper, we assess the impact of traffic fluctuation to the EMS first response availability in urban area, by evaluating the k-minute coverage under 21 traffic scenarios. The set of traffic scenarios represents the time-of-day and day-of-week effects, and is generated by combining road link speed information from multiple historical speed databases. In addition to the k-minute area coverage calculation, the k-minute population coverage is also evaluated for every 100m by 100m grid that partitions the case study area of Seoul, South Korea. In the baseline case of traveling at the speed limit, both the area and population coverage reached nearly 100% when compared to the five-minute travel time national target. Employing the proposed LoST (Loss of Serviceability due to Traffic) index, which measures coverage reduction in percentage compared to the baseline case, we find that the citywide average LoST for area and population coverage are similar at 34.2% and 33.8%. However, district-wise analysis reveals that such reduction varies significantly by district, and the magnitude of area and population coverage reduction is not always proportional. We conclude that the effect of traffic variation is significant to successful urban EMS first response performance, and regional variation is evident among local districts. Complexity in the urban environment requires a more adaptive approach in public health resource management and EMS performance target determination.

  1. Characterizing the influence of transportation infrastructure on Emergency Medical Services (EMS in urban area-A case study of Seoul, South Korea.

    Directory of Open Access Journals (Sweden)

    Jungwoo Cho

    Full Text Available In highly urbanized area where traffic condition fluctuates constantly, transportation infrastructure is one of the major contributing factors to Emergency Medical Service (EMS availability and patient outcome. In this paper, we assess the impact of traffic fluctuation to the EMS first response availability in urban area, by evaluating the k-minute coverage under 21 traffic scenarios. The set of traffic scenarios represents the time-of-day and day-of-week effects, and is generated by combining road link speed information from multiple historical speed databases. In addition to the k-minute area coverage calculation, the k-minute population coverage is also evaluated for every 100m by 100m grid that partitions the case study area of Seoul, South Korea. In the baseline case of traveling at the speed limit, both the area and population coverage reached nearly 100% when compared to the five-minute travel time national target. Employing the proposed LoST (Loss of Serviceability due to Traffic index, which measures coverage reduction in percentage compared to the baseline case, we find that the citywide average LoST for area and population coverage are similar at 34.2% and 33.8%. However, district-wise analysis reveals that such reduction varies significantly by district, and the magnitude of area and population coverage reduction is not always proportional. We conclude that the effect of traffic variation is significant to successful urban EMS first response performance, and regional variation is evident among local districts. Complexity in the urban environment requires a more adaptive approach in public health resource management and EMS performance target determination.

  2. Characterization of the Mamluk painting materials in Cairo, Egypt: El-Ashraf Bersbay Madrasa (826 A.H/ 1423 A.D a case study.

    Directory of Open Access Journals (Sweden)

    prof.Atef Brania

    2010-01-01

    Full Text Available The painting materials in the Islamic monuments in Cairo were variable and distinguished. The accurate identification and characterization of painting materials in an art object or in a paint layer is certainly an important step in the history of art, technology and conservation. The main objective of the present paper is to examine and investigate the different painting materials (pigments, gilding, binding media and painting ground employed in the decorated ceilings of Madrasa of Al-Ashraf Bersbay (Mamluk Jarkasy period. X-ray diffraction (X.R.D., scanning electron microscope SEM (EDAX, light optical microscope (LOM and fourier transform infrared spectroscopy (FTIR, together with determination of physical properties of the support (water content and density and microbiological study, adapted for analysis, investigation and evaluation of the current status. The study revealed the severe damage of painting materials. Gypsum, ultramarine, smalt, prussian blue, red ochre, emerald green, red lead (minium and gold leaves were identified in El-Ashraf Bersbay Madrasa decoration painting.

  3. Final report on case studies

    DEFF Research Database (Denmark)

    Ljungberg, Daniel; McKelvey, Maureen; Lassen, Astrid Heidemann

    2012-01-01

    Case study as a research design means investigating a single or multiple instance(s) or setting(s) (i.e. a case) and its entire context to explain a phenomenon and its processes. This is achieved through detailed understanding, usually comprised of multiple sources of information. In this way, case...... studies attempt to provide as a complete an understanding of a (complex) phenomenon as possible. Within the AEGIS project, survey and case study research are complementary. They are complementary in the sense that the former can provide more generalizable evidence on a phenomenon in terms of cross......-sectional data, while the latter can provide more in-depth (qualitative) understanding on specific issues. In systematically examining the case studies, however, this report goes beyond a typical single case study. Here we provide a synthesis of 86 case studies. Multiple case studies, following similar focus...

  4. 425 Case study

    African Journals Online (AJOL)

    Marinda

    Anaesthesia management of acute aortic dissection type B in ... of a severe, constant abdominal and chest pain radiating to the ... Continuous spinal anaesthesia was induced ... these cases surgical intervention is critical.1,2 Type B of AAD is.

  5. Comparison of Witczak NCHRP 1-40D & Hirsh dynamic modulus models based on different binder characterization methods: a case study

    Directory of Open Access Journals (Sweden)

    Khattab Ahmed M.

    2017-01-01

    Full Text Available The Pavement ME Design method considers the hot mix asphalt (HMA dynamic modulus (E* as the main mechanistic property that affects pavement performance. For the HMA, E* can be determined directly by laboratory testing (level 1 or it can be estimated using predictive equations (levels 2 and 3. Pavement-ME Design introduced the NCHRP1-40D model as the latest model for predicting E* when levels 2 or 3 HMA inputs are used. This study focused on utilizing laboratory measured E* data to compare NCHRP1-40D model with Hirsh model. This comparison included the evaluation of the binder characterization level as per Pavement ME Design and its influence on the performance of these models. E*tests were conducted in the laboratory on 25 local mixes representing different road construction projects in the kingdom of Saudi Arabia. The main tests for the mix binders were dynamic Shear Rheometer (DSR and Brookfield Rotational Viscometer (RV. Results showed that both models with level 3 binder data produced very similar accuracy. The highest accuracy and lowest bias for both models occurred with level 3 binder data. Finally, the accuracy of prediction and level of bias for both models were found to be a function of the binder input level.

  6. Contribution of the geophysical and radon techniques to characterize hydrogeological setting in the western volcanic zone of Yarmouk basin: Case study Deir El-Adas

    International Nuclear Information System (INIS)

    Al-Fares, W.; Soliman, E.; Al-Ali, A.

    2009-01-01

    The aim of this study is to illustrate the geophysical and radon techniques in characterizing ''at local scale'' a hydrogeological setting in the volcanic zone of Yarmouk basin. And to employ the obtained results to understand and explain similar hydrogeological situation related to particular subsurface geologic and tectonic structure. Based on the field observations and failed wells drilled at Deir El-Adas, and the occurrence of successful well out of that zone, all these reasons, have given us the incentive to verify and provide realistic explanation of this phenomena in the basaltic outcrops of Yarmouk basin. The interpretation of the vertical electrical surveys (VES), indicates to the presence of local faulted anticline structure of Palaeogene located under the volcanic outcrops. This structure has led to complex hydrogeological conditions, represented by limited recharge in this area which occurs through fractures and secondary faults in addition to the low direct precipitation. Piezometric map indicates to water divide in the north-west of Deir El-Adas related to the tectonic setting. Meanwhile, discharge map show low reproducibility of drilled wells in Deir El-Adas and its periphery. Due to limited radon data, it was difficult to draw concrete conclusions from this technique. (author)

  7. Esophageal intramural pseudodiverticulosis characterized by barium esophagography: a case report

    LENUS (Irish Health Repository)

    O'Connor, Owen J

    2010-05-21

    Abstract Introduction Esophageal intramural pseudodiverticulosis is a rare condition characterized by the dilatation of the submucosal glands. Case presentation We present a case of esophageal intramural pseudodiverticulosis in a 72-year-old Caucasian man who presented with dysphagia and with a background history of alcohol abuse. An upper gastrointestinal endoscopy of our patient showed an esophageal stricture with abnormal mucosal appearances, but no malignant cells were seen at biopsy. Appearances on a barium esophagram were pathognomonic for esophageal intramural pseudodiverticulosis. Conclusion We demonstrate the enduring usefulness of barium esophagography in the characterization of abnormal mucosal appearances at endoscopy.

  8. A Codesign Case Study in Computer Graphics

    DEFF Research Database (Denmark)

    Brage, Jens P.; Madsen, Jan

    1994-01-01

    The paper describes a codesign case study where a computer graphics application is examined with the intention to speed up its execution. The application is specified as a C program, and is characterized by the lack of a simple compute-intensive kernel. The hardware/software partitioning is based...

  9. Case Study Methodology and Homelessness Research

    Directory of Open Access Journals (Sweden)

    Jill Pable

    2013-10-01

    Full Text Available This paper describes the potential suitability of case study methodology for inquiry with the homeless population. It references a research study that uses case study research method to build theory. This study's topic is the lived experience of destitute individuals who reside in homeless shelters, and explores the homeless shelter built environment's potential influence on resident satisfaction and recovery. Case study methodology may be appropriate because it explores real-life contextual issues that characterize homelessness and can also accommodate the wide range of homeless person demographics that make this group difficult to study in a generalized fashion. Further, case study method accommodates the need within research in this area to understand individualized treatments as a potential solution for homelessness.

  10. Characterizing rainfall of hot arid region by using time-series modeling and sustainability approaches: a case study from Gujarat, India

    Science.gov (United States)

    Machiwal, Deepesh; Kumar, Sanjay; Dayal, Devi

    2016-05-01

    This study aimed at characterization of rainfall dynamics in a hot arid region of Gujarat, India by employing time-series modeling techniques and sustainability approach. Five characteristics, i.e., normality, stationarity, homogeneity, presence/absence of trend, and persistence of 34-year (1980-2013) period annual rainfall time series of ten stations were identified/detected by applying multiple parametric and non-parametric statistical tests. Furthermore, the study involves novelty of proposing sustainability concept for evaluating rainfall time series and demonstrated the concept, for the first time, by identifying the most sustainable rainfall series following reliability ( R y), resilience ( R e), and vulnerability ( V y) approach. Box-whisker plots, normal probability plots, and histograms indicated that the annual rainfall of Mandvi and Dayapar stations is relatively more positively skewed and non-normal compared with that of other stations, which is due to the presence of severe outlier and extreme. Results of Shapiro-Wilk test and Lilliefors test revealed that annual rainfall series of all stations significantly deviated from normal distribution. Two parametric t tests and the non-parametric Mann-Whitney test indicated significant non-stationarity in annual rainfall of Rapar station, where the rainfall was also found to be non-homogeneous based on the results of four parametric homogeneity tests. Four trend tests indicated significantly increasing rainfall trends at Rapar and Gandhidham stations. The autocorrelation analysis suggested the presence of persistence of statistically significant nature in rainfall series of Bhachau (3-year time lag), Mundra (1- and 9-year time lag), Nakhatrana (9-year time lag), and Rapar (3- and 4-year time lag). Results of sustainability approach indicated that annual rainfall of Mundra and Naliya stations ( R y = 0.50 and 0.44; R e = 0.47 and 0.47; V y = 0.49 and 0.46, respectively) are the most sustainable and dependable

  11. Molecular characterization of misidentified Plasmodium ovale imported cases in Singapore.

    Science.gov (United States)

    Chavatte, Jean-Marc; Tan, Sarah Bee Hui; Snounou, Georges; Lin, Raymond Tzer Pin Valentine

    2015-11-14

    Plasmodium ovale, considered the rarest of the malaria parasites of humans, consists of two morphologically identical but genetically distinct sympatric species, Plasmodium ovale curtisi and Plasmodium ovale wallikeri. These parasites resemble morphologically to Plasmodium vivax with which they also share a tertian periodicity and the ability to cause relapses, making them easily misidentified as P. vivax. Plasmodium ovale infections are rarely reported, but given the likelihood of misidentification, their prevalence might be underestimated. Morphological and molecular analysis of confirmed malaria cases admitted in Singapore in 2012-2014 detected nine imported P. ovale cases that had been misidentified as P. vivax. Since P. ovale had not been previously officially reported in Singapore, a retrospective analysis of available, frozen, archival blood samples was performed and returned two additional misidentified P. ovale cases in 2003 and 2006. These eleven P. ovale samples were characterized with respect to seven molecular markers (ssrRNA, Potra, Porbp2, Pog3p, dhfr-ts, cytb, cox1) used in recent studies to distinguish between the two sympatric species, and to a further three genes (tufa, clpC and asl). The morphological features of P. ovale and the differential diagnosis with P. vivax were reviewed and illustrated by microphotographs. The genetic dimorphism between P. ovale curtisi and P. ovale wallikeri was assessed by ten molecular markers distributed across the three genomes of the parasite (Genbank KP050361-KP050470). The data obtained for seven of these markers were compared with those published and confirmed that both P. ovale species were present. This dimorphism was also confirmed for the first time on: (1) two genes from the apicoplast genome (tufA and clpC genes); and, (2) the asl gene that was used for phylogenetic analyses of other Plasmodium species, and that was found to harbour the highest number of dimorphic loci between the two P. ovale species

  12. Approximated empirical correlations to the characterization of physical and geometrical properties of solid particulate biomass: case studies of the elephant grass and sugar cane trash

    Energy Technology Data Exchange (ETDEWEB)

    Olivares Gomez, Edgardo; Cortez, Luis A. Barbosa [Universidade Estadual de Campinas (FEAGRI/UNICAMP), SP (Brazil). Fac. de Engenharia Agricola. Lab. de Termodinamica e Energia; Alarcon, Guillermo A. Rocca; Perez, Luis E. Brossard [Universidad de Oriente, Santiago de Cuba (Cuba)

    2008-07-01

    Two types of biomass solid particles, elephant grass (Pennisetum purpureum Schum. variety) and sugar cane trash, were studied in laboratory in order to obtain information about several physical and geometrical properties. In the both case, the length, breadth, and thickness of fifty particles selected randomly from each fraction of the size class, obtained by mechanical fractionation through sieves, were measured manually given their size. A geometric model of type rectangular base prism was adopted because based on observations it was demonstrated that the most of particles that were measured exhibited length which was significantly greater that width ( l >> a ). From these measurements average values for other properties were estimated, for example, characteristic dimension of particle, projected area of the rectangular prism, area of the prism rectangular section, volume of the rectangular prism, shape factors, sphericity, particles specific superficial area and equivalent diameter. A statistical analysis was done and proposed empirical and semi-empirical mathematical correlation models obtained by lineal regression, which show a goodness of fit of these equations to the reported experimental data. (author)

  13. Molecular characterization of free tropospheric aerosol collected at the Pico Mountain Observatory: a case study with a long-range transported biomass burning plume

    Science.gov (United States)

    Dzepina, K.; Mazzoleni, C.; Fialho, P.; China, S.; Zhang, B.; Owen, R. C.; Helmig, D.; Hueber, J.; Kumar, S.; Perlinger, J. A.; Kramer, L. J.; Dziobak, M. P.; Ampadu, M. T.; Olsen, S.; Wuebbles, D. J.; Mazzoleni, L. R.

    2015-05-01

    Free tropospheric aerosol was sampled at the Pico Mountain Observatory located at 2225 m above mean sea level on Pico Island of the Azores archipelago in the North Atlantic. The observatory is located ~ 3900 km east and downwind of North America, which enables studies of free tropospheric air transported over long distances. Aerosol samples collected on filters from June to October 2012 were analyzed to characterize organic carbon, elemental carbon, and inorganic ions. The average ambient concentration of aerosol was 0.9 ± 0.7 μg m-3. On average, organic aerosol components represent the largest mass fraction of the total measured aerosol (60 ± 51%), followed by sulfate (23 ± 28%), nitrate (13 ± 10%), chloride (2 ± 3%), and elemental carbon (2 ± 2%). Water-soluble organic matter (WSOM) extracted from two aerosol samples (9/24 and 9/25) collected consecutively during a pollution event were analyzed using ultrahigh-resolution electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Approximately 4000 molecular formulas were assigned to each of the mass spectra in the range of m/z 100-1000. The majority of the assigned molecular formulas had unsaturated structures with CHO and CHNO elemental compositions. FLEXPART retroplume analyses showed the sampled air masses were very aged (average plume age > 12 days). These aged aerosol WSOM compounds had an average O/C ratio of ~ 0.45, which is relatively low compared to O/C ratios of other aged aerosol. The increase in aerosol loading during the measurement period of 9/24 was linked to biomass burning emissions from North America by FLEXPART retroplume analysis and Moderate Resolution Imaging Spectroradiometer (MODIS) fire counts. This was confirmed with biomass burning markers detected in the WSOM and with the morphology and mixing state of particles as determined by scanning electron microscopy. The presence of markers characteristic of aqueous-phase reactions of phenolic species suggests

  14. Clinical and genetic characterization of six cases with complete ...

    Indian Academy of Sciences (India)

    The clinical examinations such as sex hormone test and B ultrasound were performed and the genetic characterization of patients were evaluated by karyotype analysis, polymerase chain reaction and DNA sequencing. The six cases with 46, XY karyotype were diagnosed with CAIS and four novel AR mutations were ...

  15. Emotion, Engagement, and Case Studies

    Science.gov (United States)

    Herreid, Clyde Freeman; Terry, David R.; Lemons, Paula; Armstrong, Norris; Brickman, Peggy; Ribbens, Eric

    2014-01-01

    Three college faculty taught large general biology classes using case studies and personal response systems (clickers). Each instructor taught the same eight cases in two different sections, except the questions within the cases differed. In one section the questions were lower order (LO) factual inquiries, and in the other they were largely…

  16. Development of an integrative approach for the characterization of environmental risk on marine transition ecosystems: the Sado estuary as a case study

    Directory of Open Access Journals (Sweden)

    Filipa Maria Pereira

    2014-05-01

    Full Text Available Estuaries and transitional waters are important ecosystems from which organisms and humans are dependent on for survival. They are important as nursery areas and shelter for many aquatic organisms, from which humans and their economical activities are dependent on. Humans also depend on estuaries for other reasons such as tourism, heavy industry, aquaculture and shipping. The degradation of estuarine environmental quality implies ecologic, economic and social prejudice, so it is important to evaluate the state of the environment to assist management. The Sado estuary (SW Portugal is considered moderately contaminated. The area is impacted by diverse human activities, from shipping, industry, urbanism and even mariculture and agriculture activities. Because Sado estuary is very important for human and ecological reasons, many studies were conducted by several researchers in past few years, albeit scattered. As such, there was a need to integrate the information hitherto produced, in order to obtain a clear and complete image of the overall environmental quality status of the area, to assist future management plans and decision-making. For the purpose, a geographical information system (GIS was created from sediment contamination and biomarker data collected from a decade-long time-series of publications. Five distinct areas were identified from the Sado estuary: a clean area plus four contaminated areas characterized by distinct sediment contamination patterns, related to different pollution hot spots and diffuse contamination sources. Also, in spite of the multiple biological traits under survey, the biomarker data (from several organisms are in general agreement with the environmental contamination georeferencing information. Through this evaluation, the main anthropogenic sources of pollutants were identified, namely, the shipyard area and adjacent industrial belt, followed by urban and agricultural inputs into the estuary. From the data it is

  17. Building theories from case study research: the progressive case study

    NARCIS (Netherlands)

    Steenhuis, H.J.; de Bruijn, E.J.

    2006-01-01

    Meredith (1998) argues for more case and field research studies in the field of operations management. Based on a literature review, we discuss several existing approaches to case studies and their characteristics. These approaches include; the Grounded Theory approach which proposes no prior

  18. Characterization of the Mamluk painting materials in Cairo, Egypt: El-Ashraf Bersbay Madrasa (826 A.H/ 1423 A.D) a case study.

    OpenAIRE

    prof.Atef Brania

    2010-01-01

    The painting materials in the Islamic monuments in Cairo were variable and distinguished. The accurate identification and characterization of painting materials in an art object or in a paint layer is certainly an important step in the history of art, technology and conservation. The main objective of the present paper is to examine and investigate the different painting materials (pigments, gilding, binding media and painting ground) employed in the decorated ceilings of Madrasa of Al-Ashraf...

  19. Theory Testing Using Case Studies

    DEFF Research Database (Denmark)

    Møller, Ann-Kristina Løkke; Dissing Sørensen, Pernille

    2014-01-01

    The appropriateness of case studies as a tool for theory testing is still a controversial issue, and discussions about the weaknesses of such research designs have previously taken precedence over those about its strengths. The purpose of the paper is to examine and revive the approach of theory...... testing using case studies, including the associated research goal, analysis, and generalisability. We argue that research designs for theory testing using case studies differ from theorybuilding case study research designs because different research projects serve different purposes and follow different...... research paths....

  20. Theory testing using case studies

    DEFF Research Database (Denmark)

    Dissing Sørensen, Pernille; Løkke Nielsen, Ann-Kristina

    2006-01-01

    on the strengths of theory-testing case studies. We specify research paths associated with theory testing in case studies and present a coherent argument for the logic of theoretical development and refinement using case studies. We emphasize different uses of rival explanations and their implications for research...... design. Finally, we discuss the epistemological logic, i.e., the value to larger research programmes, of such studies and, following Lakatos, conclude that the value of theory-testing case studies lies beyond naïve falsification and in their contribution to developing research programmes in a progressive......Case studies may have different research goals. One such goal is the testing of small-scale and middle-range theories. Theory testing refers to the critical examination, observation, and evaluation of the 'why' and 'how' of a specified phenomenon in a particular setting. In this paper, we focus...

  1. Fuzzy-Set Case Studies

    Science.gov (United States)

    Mikkelsen, Kim Sass

    2017-01-01

    Contemporary case studies rely on verbal arguments and set theory to build or evaluate theoretical claims. While existing procedures excel in the use of qualitative information (information about kind), they ignore quantitative information (information about degree) at central points of the analysis. Effectively, contemporary case studies rely on…

  2. Methodology for the case studies

    NARCIS (Netherlands)

    Smits, M.J.W.; Woltjer, G.B.

    2017-01-01

    This document is about the methodology and selection of the case studies. It is meant as a guideline for the case studies, and together with the other reports in this work package can be a source of inform ation for policy officers, interest groups and researchers evaluating or performing impact

  3. Case study - Argentina

    International Nuclear Information System (INIS)

    Diaz, E.

    1986-01-01

    Antecedents and experience of nuclear activities in Argentina; the Atomic Energy Commission (CNEA). First development and research activities. Research reactors and radioisotopes plants. Health physics and safety regulations. - Feasibility studies for the first nuclear power plant. Awarding the first plant CNA I (Atucha I). Relevant data related to the different project stages. Plant performance. - Feasibility study for the second nuclear power plant. Awarding the second plant CNE (Central Nuclear Embalse). Relevant data related to established targets. Differences compared with the first station targets. Local participation. Plant performance. (orig./GL)

  4. Characterization of rabies virus from a human case in Nepal.

    Science.gov (United States)

    Pant, G R; Horton, D L; Dahal, M; Rai, J N; Ide, S; Leech, S; Marston, D A; McElhinney, L M; Fooks, A R

    2011-04-01

    Rabies is endemic throughout most of Asia, with the majority of human cases transmitted by domestic dogs (Canis familiaris). Here, we report a case of rabies in a 12-year-old girl in the Lalitpur district of Nepal that might have been prevented by better public awareness and timely post-exposure prophylaxis. Molecular characterization of the virus showed 100% identity over a partial nucleoprotein gene sequence to previous isolates from Nepal belonging to the 'arctic-like' lineage of rabies virus. Sequence analysis of both partial nucleoprotein and glycoprotein genes showed differences in consensus sequence after passage in vitro but not after passage in vivo.

  5. Case Study: Shiraz Women

    Directory of Open Access Journals (Sweden)

    Bijan Khajehnoori

    2011-04-01

    Full Text Available This study investigated the relationship between lifestyle which seems as a scale of globalization process with body image. Required data was collected by systematic random sampling among 508 women in Shiraz. Based on existing theories and studies theoretical framework has constituted based on Giddens theory. Six hypotheses have been established. For collecting information, survey method and self reported questionnaire were used. In data analysis and explanation, multiple regression and unilateral dispersion analyses were used. The result showed that among effective factors on body image, modern musical lifestyle, religious' lifestyle, leisure lifestyle and participative lifestyle explained 23 percent of variations of body image. Among these variables, only religious lifestyle had negative relationship with body image and other variables had positive relationship with dependant variable.

  6. Centrifugal compressor case study

    Energy Technology Data Exchange (ETDEWEB)

    Eckert, B.

    2010-10-15

    Three centrifugal compressors at a pipeline station were retrofitted with higher head impellers in 2008. The owners of the station experienced vibration problems over the following 2 years that caused transmitter and position failures that were assumed to be flow-induced pulsations. A vibration and pulsation analysis indicated that the shell mode piping vibration excited by the blade pass pulsation was responsible for the failures. This study outlined factors that contributed to the vibration problem. Interferences between the compressor and shell mode piping natural frequencies were predicted, and potential excitation sources were examined. The study demonstrated how centrifugal vibration analyses can be used during the design phase to avoid costly adjustments. Recommendations included the addition of stiffeners to alter the shell modes, and the addition of constrained layer damping material to reduce resonant responses. 2 refs., 1 tab., 12 figs.

  7. Case study: Tourism marketing

    OpenAIRE

    Kennell, James

    2014-01-01

    Tourism can be a challenging subject for students because it is both dynamic and susceptible to economic turbulence and shifts in trends. Tourism: A Modern Synthesis is an essential textbook for tourism students looking for a clear and comprehensive introduction to their studies which helps overcome these challenges. The authors apply a strong business approach to the subject reflecting developments in the teaching and content of modern courses and the text covers both key principles and cont...

  8. Analysis of particulate matter in anthropized areas characterized by the presence of crude oil pre-treatment plants: The case study of the Agri Valley (Southern Italy)

    Science.gov (United States)

    Trippetta, Serena; Caggiano, Rosa; Telesca, Luciano

    2013-10-01

    Simultaneous measurements of PM10, PM2.5 and PM1 (i.e., aerosol particles with aerodynamic diameter less than 10, 2.5 and 1 μm, respectively) daily mass concentrations and daily particle number concentration were performed for the first time in Agri Valley (Basilicata Region - Southern Italy) from July to November 2011. This area is characterized by anthropogenic activities having high potential environmental and human health impacts. In fact, the Agri Valley houses the largest European on-shore reservoir and the largest crude oil pre-treatment plant within an anthropized area. The PM measurements were analyzed combining an innovative statistical methodology, the Singular Spectral Analysis, with forecast models and remote sensing observations. Our findings show that most of the PM collected was made up of particles in the fine and sub-micrometric fractions (i.e., PM2.5 and PM1, respectively) very likely originated by common anthropogenic sources. Moreover, PM2.5 and PM1 daily mass concentrations were characterized by a slightly increasing trend that could be related to the contribution of local sources, such as the crude oil pre-treatment plant, whose combustion processes also produce the emission of particles mainly in the fine and sub-micrometric size ranges. The integrated use of model forecasts, satellite observations and in-situ measurements shows that the only PM10 exceedance was affected by the contribution of Saharan dust, while the three PM2.5 exceedances were mainly due to local anthropogenic sources. Finally, the analysis of the PM10 and PM2.5 Air Quality Index (AQI) values shows that air quality was always “good” with respect to PM10 and “moderate” with respect to PM2.5 suggesting that fine particles, if they will be not kept under control, should represent a real problem also posing health risks to the population living close to the crude oil pre-treatment plant.

  9. Case Study: Derechos Digitales

    Directory of Open Access Journals (Sweden)

    Cameron Neylon

    2017-10-01

    Full Text Available Derechos Digitales is a Latin American advocacy and research network focussed on freedom on the internet, privacy and copyright reform. For the pilot project a specific IDRC funded project was the notional focus of study. However in practice the effort for considering data sharing was aimed at being organisation wide. The organisation already shares reports and other resources (particularly images and infographics by default. While open data was described as being “in the DNA of the organisation” there was little practice across the network of sharing preliminary and in-process materials. Some aspects of data collection on research projects, particularly to do with copyright and legal issues, have significant privacy issues and as the organisation focuses on privacy as one of its advocacy areas this is taken very seriously. Many materials from research projects are not placed online at all. Derechos Digitales run distributed projects and this creates challenges for consistent management. Alongside this the main contact at DD changed during the course of the pilot. This exchange exemplified the challenges of maintaining organisational systems and awareness through a personnel change.

  10. Case study: Khoramdareh County

    Directory of Open Access Journals (Sweden)

    Vahid Riahi Riahi

    2016-10-01

    Full Text Available Environmental sustainability of rural settlements based on a systematic viewpoint may be defined as a realization of sustainable development in different social, economic and environmental aspects of rural areas. Achieving this goal requires that we pay more attention to effective elements and factors through a set of sustainability indices. This research was meant to analyze sustainable factors of rural settlement in three dimensions: environmental, social and economic context using multi-criteria decision analysis and explanation of the relationships between its active and effective factors in the rural area of the Khorramdarreh County in the province of Zanjan. The research method used is the descriptive analytic approach. Data from 287 households were sampled randomly from a total of 1143 households in the four villages including: Rahmat Abad, Alvand, Baghdareh and, Sukhariz (out of 15 villages in the Khorramdarreh County. In the process of doing this research and after calculating the weights, the difference in the sustainability of environmental, social, economic and physical aspects in rural areas of this county have been determined. Data was collected using library and field research through questionnaires. Data analysis was performed by the One-Sample t Test and the Vikur and path analysis techniques, using statistical software SPSS. The findings show that environmental sustainability in the study area is half desirable. Among the different aspects of environmental sustainability, the most effective factors are physical, economic, social and environmental aspects, respectively. Little attention of policy-making –system to socio-cultural and environmental aspects, especially in practice, and rapid and unplanned utilization of production resources are the most important factors affecting this situation in two given dimensions. Although, in programmed documents the planning system agents emphasize on the socio-cultural sustainability

  11. Characterization and distribution of organic matter using specific physico-chemical methods: A case study of the southeast Adriatic continental and shelf slope (Albania)

    Science.gov (United States)

    Plavšić, Marta; Strmečki, Slađana; Dautović, Jelena; Vojvodić, Vjeročka; Olujić, Goran; Ćosović, Božena

    2012-05-01

    In May 2009, we characterized the organic matter in the area where Albanian shelf riverine plume waters enter the Southern Adriatic Pit region. Due to stable weather and hydrological conditions at the time of sampling a longitudinal thermal front was present around the Albanian shelf break. Our measurements point to the input of inorganic nutrients, including phosphorus (average P-PO4 concentration was 0.71 μg/L) and nitrogen (average as total inorganic nitrogen (TIN) concentration was 25.33 μg/L) due to the intrusion of Levantine Intermediate Water (LIW) through the Otranto Strait. The input of LIW brings high salinity (˜38.7) water that is poor in organic matter content. Low concentrations of dissolved organic carbon (DOC) (0.7 mg C/L) and particulate organic carbon (POC) (0.06 mg C/L), surface active substances (SAS) (in the range from 0.025 to 0.078 mg/L equiv. Triton-X-100) and copper complexing capacity (CuCC) (24 nmol Cu2+/L) were measured in the area. All the values for DOC, POC, SAS and CuCC were significantly lower in the Albanian coastal waters than in the North Adriatic. The measurable influence of the inflowing Albanian rivers was observed from the inverse dependance of the DOC concentrations and salinity data. The Albanian rivers contribute to the elevated nutrient concentrations especially those of silicate, which displayed concentrations up to 380 μg/L in the shallowest coastal station.

  12. The ecological competition and grazing reverse the effects of sulfamethoxazole on plankton: a case study on characterizing community-level effect.

    Science.gov (United States)

    Wang, Changyou; Liang, Shengkang; Zhang, Yong

    2018-04-12

    The toxic effects of sulfamethoxazole (SMX) on densities of two algae, Platymonas helgolandica var. tsingtaoensis, Isochrysis galbana, and of a rotifer, Brachionus plicatilis, were tested by the population and community experiments. Two endpoints, the carrying capacity and the densities array of community in steady state (DACS), were used to characterize the toxic effects at a population level and a community one, respectively. The results showed that the carrying capacity of P. helgolandica var. tsingtaoensis and B. plicatilis did not decline significantly in population test when the concentration of SMX was lower than 6.0 mg L -1 and 12.0 mg L -1 , respectively. However, I. galbana was sensitive to SMX and had presented toxic effect at 3.0 mg L -1 . By extrapolation of toxic effect at a population level to a community one, a derived community-NOEC was 3.0 mg L -1 , representing an inference from data of toxic effects at population level. In community experiment, when the customized community was in steady state, the density of I. galbana increased as a whole with SMX concentration in the range of tested concentration (0-144 mg L -1 ), while that of P. helgolandica var. tsingtaoensis assumed the trend of a reversed "v" in this range. Only the density of B. plicatilis decreased with SMX concentration. With the DACS as endpoint, a NOEC for the customized community was determined to be 6.0 mg L -1 . This indicates that interspecific interactions can reverse the toxic effects of SMX on phytoplankton. The DACS was reliable and stable, serving as the endpoints in assessment of the effects of the pollutants on the ecosystems.

  13. Characterizing heterogeneity of disease incidence in a spatial hierarchy: a case study from a decade of observations of fusarium head blight of wheat.

    Science.gov (United States)

    Kriss, A B; Paul, P A; Madden, L V

    2012-09-01

    A multilevel analysis of heterogeneity of disease incidence was conducted based on observations of Fusarium head blight (caused by Fusarium graminearum) in Ohio during the 2002-11 growing seasons. Sampling consisted of counting the number of diseased and healthy wheat spikes per 0.3 m of row at 10 sites (about 30 m apart) in a total of 67 to 159 sampled fields in 12 to 32 sampled counties per year. Incidence was then determined as the proportion of diseased spikes at each site. Spatial heterogeneity of incidence among counties, fields within counties, and sites within fields and counties was characterized by fitting a generalized linear mixed model to the data, using a complementary log-log link function, with the assumption that the disease status of spikes was binomially distributed conditional on the effects of county, field, and site. Based on the estimated variance terms, there was highly significant spatial heterogeneity among counties and among fields within counties each year; magnitude of the estimated variances was similar for counties and fields. The lowest level of heterogeneity was among sites within fields, and the site variance was either 0 or not significantly greater than 0 in 3 of the 10 years. Based on the variances, the intracluster correlation of disease status of spikes within sites indicated that spikes from the same site were somewhat more likely to share the same disease status relative to spikes from other sites, fields, or counties. The estimated best linear unbiased predictor (EBLUP) for each county was determined, showing large differences across the state in disease incidence (as represented by the link function of the estimated probability that a spike was diseased) but no consistency between years for the different counties. The effects of geographical location, corn and wheat acreage per county, and environmental conditions on the EBLUP for each county were not significant in the majority of years.

  14. Technological characterization of a mineral deposit. A case study: the niobium of Catalao I, Goias State, Brazil; Caracterizacao tecnologica de um deposito mineral. Um estudo de caso: o niobio de Catalao I, Goias

    Energy Technology Data Exchange (ETDEWEB)

    Sant` Agostino, Lilia Mascarenhas

    1997-12-31

    This thesis presents a contribution to the subject of ore technological characterization integrated to orebody context, regarding sample, ore characteristics, ore types definition and distribution through the mineral occurrence, and ore reserves modeling using technological parameters. A professional experience in this specialization based a conceptual discussion of the matter, supported by a practical approach. The initial approach is the subject definition, and it`s importance for technological and economical feasibility studies, in all phases of mining research and development, as a tool for beneficiation alternatives definition. The multidisciplinary aspect of the knowledge involved for ore characterization is remarked, considering that is an interface segment to be conduced interactively with others. It is an applied mineralogy, that needs some geological and some ore dressing imputes. After the general considerations about importance and applicability, it follows a methodological approach of laboratory procedures and analytical techniques, as a result of practical experience acquired in the study of several ores. The main points discussed are related with criterion to organized laboratory preparation scheme and to select appropriated analytical techniques, without detailing them, for what some specialized bibliography is indicated. Finalizing the theoretical explanation, there is a concise description about computers resources for 3D orebody modeling, and integrated software applied for geology and mining. For illustration, it is exposed a complex ore case study: niobium mineralization associated with the alkaline-carbonatitic occurrence of Catalao I, located in Goias State, Brazil. Besides the explanation of laboratory procedures and methods applied, results treatment and interpretation are emphasized, under both characterization and economic point of view. (author) 135 refs., 57 figs., 38 tabs.

  15. Technological characterization of a mineral deposit. A case study: the niobium of Catalao I, Goias State, Brazil; Caracterizacao tecnologica de um deposito mineral. Um estudo de caso: o niobio de Catalao I, Goias

    Energy Technology Data Exchange (ETDEWEB)

    Sant`Agostino, Lilia Mascarenhas

    1996-12-31

    This thesis presents a contribution to the subject of ore technological characterization integrated to orebody context, regarding sample, ore characteristics, ore types definition and distribution through the mineral occurrence, and ore reserves modeling using technological parameters. A professional experience in this specialization based a conceptual discussion of the matter, supported by a practical approach. The initial approach is the subject definition, and it`s importance for technological and economical feasibility studies, in all phases of mining research and development, as a tool for beneficiation alternatives definition. The multidisciplinary aspect of the knowledge involved for ore characterization is remarked, considering that is an interface segment to be conduced interactively with others. It is an applied mineralogy, that needs some geological and some ore dressing imputes. After the general considerations about importance and applicability, it follows a methodological approach of laboratory procedures and analytical techniques, as a result of practical experience acquired in the study of several ores. The main points discussed are related with criterion to organized laboratory preparation scheme and to select appropriated analytical techniques, without detailing them, for what some specialized bibliography is indicated. Finalizing the theoretical explanation, there is a concise description about computers resources for 3D orebody modeling, and integrated software applied for geology and mining. For illustration, it is exposed a complex ore case study: niobium mineralization associated with the alkaline-carbonatitic occurrence of Catalao I, located in Goias State, Brazil. Besides the explanation of laboratory procedures and methods applied, results treatment and interpretation are emphasized, under both characterization and economic point of view. (author) 135 refs., 57 figs., 38 tabs.

  16. Fuels characterization studies. [jet fuels

    Science.gov (United States)

    Seng, G. T.; Antoine, A. C.; Flores, F. J.

    1980-01-01

    Current analytical techniques used in the characterization of broadened properties fuels are briefly described. Included are liquid chromatography, gas chromatography, and nuclear magnetic resonance spectroscopy. High performance liquid chromatographic ground-type methods development is being approached from several directions, including aromatic fraction standards development and the elimination of standards through removal or partial removal of the alkene and aromatic fractions or through the use of whole fuel refractive index values. More sensitive methods for alkene determinations using an ultraviolet-visible detector are also being pursued. Some of the more successful gas chromatographic physical property determinations for petroleum derived fuels are the distillation curve (simulated distillation), heat of combustion, hydrogen content, API gravity, viscosity, flash point, and (to a lesser extent) freezing point.

  17. Case studies in conservation science

    Science.gov (United States)

    Bisulca, Christina

    The research presented in this dissertation covers three separate topics of conservation as defined by the National Science Foundation: 1) Materials Stabilization, Strengthening, Monitoring, and Repair; 2. Understanding Material Degradation and Aging; and 3) Materials and Structural Characterization of Cultural Heritage Objects (the 'technical study'). The first topic is addressed through a study to assess the consolidant tetraethoxysilane for the stabilization of alum treated wood. Falling under materials degradation studies is a study published in American Museum Novitates to understand how environmental conditions affect the aging of fossil resins from five different deposits. Two separate studies are included in technical study of cultural heritage objects which comprises the third research area of materials characterization. The first is a survey of red dyes used in Chinese paintings from the Ming Dynasty to the Early Republic (1364-1911). The second is a study of the pigments, dyes and binders used in Hawaiian barkcloth (kapa) from the 19th century.

  18. Case studies of uncommon headaches.

    Science.gov (United States)

    Evans, Randolph W

    2006-05-01

    The following interesting and uncommon headache disorders are presented through case studies: exploding head syndrome, hypnic headache, neck-tongue syndrome, "Alice in Wonderland" syndrome, nummular headache, red ear syndrome, burning mouth syndrome, spontaneous intracranial hypotension syndrome, and cardiac cephalalgia.

  19. a case study ondo state

    African Journals Online (AJOL)

    user

    the design of a Government Cloud (G-Cloud) network for Ondo State Government which will ... network for a developing economy; a case study of ... France is one of those countries that favour .... Arequipa city. .... Where region 0 = Akure, 1 =.

  20. Discovery and characterization of submarine groundwater discharge in the Siberian Arctic seas: A case study in Buor-Khaya Gulf, Laptev Sea

    OpenAIRE

    Charkin, Alexander N.; Rutgers van der Loeff, Michiel; Shakhova, Natalia E.; Gustafsson, Örjan; Dudarev, Oleg V.; Cherepnev, Maxim S.; Salyuk, Anatoly N.; Koshurnikov, Andrey V.; Spivak, Eduard A.; Gunar, Alexey Y.; Semiletov, Igor P.

    2017-01-01

    It has been suggested that increasing freshwater discharge to the Arctic Ocean may also occur as submarine groundwater discharge (SGD), yet there are no direct observations of this phenomenon in the Arctic shelf seas. This study tests the hypothesis that SGD does exist in the Siberian-Arctic shelf seas but its dynamics may be largely controlled by complicated geocryological conditions such as permafrost. The field-observational approach in the southeast Laptev Sea used a combination of hydrol...

  1. A Combined SAXS/SANS Study for the in Situ Characterization of Ligand Shells on Small Nanoparticles: The Case of ZnO.

    Science.gov (United States)

    Schindler, T; Schmiele, M; Schmutzler, T; Kassar, T; Segets, D; Peukert, W; Radulescu, A; Kriele, A; Gilles, R; Unruh, T

    2015-09-22

    ZnO nanoparticles (NPs) have great potential for their use in, e.g., thin film solar cells due to their electro-optical properties adjustable on the nanoscale. Therefore, the production of well-defined NPs is of major interest. For a targeted production process, the knowledge of the stabilization layer of the NPs during and after their formation is of particular importance. For the study of the stabilizer layer of ZnO NPs prepared in a wet chemical synthesis from zinc acetate, only ex situ studies have been performed so far. An acetate layer bound to the surface of the dried NPs was found; however, an in situ study which addresses the stabilizing layer surrounding the NPs in a native dispersion was missing. By the combination of small angle scattering with neutrons and X-rays (SANS and SAXS) for the same sample, we are now able to observe the acetate shell in situ for the first time. In addition, the changes of this shell could be followed during the ripening process for different temperatures. With increasing size of the ZnO core (d(core)) the surrounding shell (d(shell)) becomes larger, and the acetate concentration within the shell is reduced. For all samples, the shell thickness was found to be larger than the maximum extension of an acetate molecule with acetate concentrations within the shell below 50 vol %. Thus, there is not a monolayer of acetate molecules that covers the NPs but rather a swollen shell of acetate ions. This shell is assumed to hinder the growth of the NPs to larger macrostructures. In addition, we found that the partition coefficient μ between acetate in the shell surrounding the NPs and the total amount of acetate in the solution is about 10% which is in good agreement with ex situ data determined by thermogravimetric analysis.

  2. Environmental and geologic site characterization: A case study of Monte Argentario promontory; Recupero geologico-ambientale: un esempio rappresentativo di studio sul promontorio di Monte Argentario

    Energy Technology Data Exchange (ETDEWEB)

    Andriola, L.; Cautilli, F.; Polizzano, C.; Tassoni, E. [ENEA, Centro Ricerche Casaccia, Rome (Italy). Dip. Ambiente

    1996-12-01

    The topic discussed in this report can be inserted within the context of studies carried out by ENEA (Italian Agency for New Technologies, Energy and the Environment) on the Monte Argentario. These studies showed a noteworthy group of geological phenomena and the need to promote articulate and differentiated interventions for which professionalism and operative capability are absolutely indispensable, qualities which are typical of a body such as ENEA. The ENEA has therefore set up a method of intervention which represents a cultural instrument necessary if one is to have the correct approach to environmental problems connected to sliding movements. The topics dealt with in the present technical report represent the summary of different investigations carried out on the promontory. The report mainly provides a classification of sliding movements and the works usually carried out to improve areas of the territory which show elevated levels of degradation and slope instability, for each coastal areas of the promontory, detailed conceptual indications are provided regarding the works required with the scope of lessening the present risks in the above mentioned areas.

  3. Discovery and characterization of submarine groundwater discharge in the Siberian Arctic seas: a case study in the Buor-Khaya Gulf, Laptev Sea

    Science.gov (United States)

    Charkin, Alexander N.; Rutgers van der Loeff, Michiel; Shakhova, Natalia E.; Gustafsson, Örjan; Dudarev, Oleg V.; Cherepnev, Maxim S.; Salyuk, Anatoly N.; Koshurnikov, Andrey V.; Spivak, Eduard A.; Gunar, Alexey Y.; Ruban, Alexey S.; Semiletov, Igor P.

    2017-10-01

    It has been suggested that increasing terrestrial water discharge to the Arctic Ocean may partly occur as submarine groundwater discharge (SGD), yet there are no direct observations of this phenomenon in the Arctic shelf seas. This study tests the hypothesis that SGD does exist in the Siberian Arctic Shelf seas, but its dynamics may be largely controlled by complicated geocryological conditions such as permafrost. The field-observational approach in the southeastern Laptev Sea used a combination of hydrological (temperature, salinity), geological (bottom sediment drilling, geoelectric surveys), and geochemical (224Ra, 223Ra, 228Ra, and 226Ra) techniques. Active SGD was documented in the vicinity of the Lena River delta with two different operational modes. In the first system, groundwater discharges through tectonogenic permafrost talik zones was registered in both winter and summer. The second SGD mechanism was cryogenic squeezing out of brine and water-soluble salts detected on the periphery of ice hummocks in the winter. The proposed mechanisms of groundwater transport and discharge in the Arctic land-shelf system is elaborated. Through salinity vs. 224Ra and 224Ra / 223Ra diagrams, the three main SGD-influenced water masses were identified and their end-member composition was constrained. Based on simple mass-balance box models, discharge rates at sites in the submarine permafrost talik zone were 1. 7 × 106 m3 d-1 or 19.9 m3 s-1, which is much higher than the April discharge of the Yana River. Further studies should apply these techniques on a broader scale with the objective of elucidating the relative importance of the SGD transport vector relative to surface freshwater discharge for both water balance and aquatic components such as dissolved organic carbon, carbon dioxide, methane, and nutrients.

  4. Local Site Characterization Using HVSR, ReMi, and SPAC, Study Case: Soccer Field At Autonomous University of Santo Domingo, Dominican Republic

    Science.gov (United States)

    Upegui Botero, F. M.; Rojas Mercedes, N.; Huerta-Lopez, C.; Martinez-Cruzado, J. A.; Suárez, L.; Lopez, A. M.; Huerfano Moreno, V.

    2013-12-01

    Earthquake effects are frequently quantified by the energy liberated at the source, and the degree of damage produced in urban areas. The damage of historic events such as the Mw=8.3, September 19, 1985 Mexico City Earthquake was dominated by the amplification of seismic waves due to local site conditions. The assessment of local site effects can be carried out with site response analyses in order to determine the properties of the subsoil such as the dominant period, and the Vs30. The evaluation of the aforementioned properties is through the analysis of ground motion. However, in locations with low seismicity, the most convenient method to assess the site effect is the analysis of ambient vibration measurements. The Spatial Auto Correlation method (SPAC) can be used to determine a Vs30 model from ambient vibration measurements using a triangular array of sensors. Refraction Microtremor (ReMi) considers the phase velocity of the Rayleigh waves can be separated of apparent velocities; the aim of the ReMI method is to obtain the Vs30 model. The HVSR technique or Nakamura's method has been adopted to obtain the resonant frequency of the site from the calculation of ratio between the Fourier amplitude spectra or PSD spectrum of the horizontal and vertical components of ambient vibration. The aim of this work is to compare the results using different techniques to assess local site conditions in the urban area of Santo Domingo, Dominican Republic. The data used was collected during the Pan-American Advance Studies Institute (PASI), Workshop held in Santo Domingo, Dominican Republic from July 14 to 25, 2013. The PASI was sponsored by IRIS Consortium, NSF and DOE. Results obtained using SPAC, and ReMi, show a comparable model of surface waves velocities. In addition to the above, the HVSR method is combined with the stiffness matrices method for layered soils to calculate a model of velocities and the predominant period on the site. As part of this work a comparison with

  5. Characterizing fragmentation of the collective forests in southern China from multitemporal Landsat imagery: A case study from Kecheng district of Zhejiang province

    Science.gov (United States)

    Li, M.; Zhu, Z.; Vogelmann, James E.; Xu, D.; Wen, W.; Liu, A.

    2011-01-01

    Tropical and subtropical forests provide important ecosystem goods and services including carbon sequestration and biodiversity conservation. These forests are facing increasing socioeconomic pressures and are rapidly being degraded and fragmented. This analysis focuses on the rate of change and patterns of fragmentation in a collective forest area in Zhejiang province, China, during the time period 1988–2005. The research consisted of two parts. The first was the development of general land cover maps and the identification of land cover changes by interpreting Landsat Thematic Mapper (TM) and Enhanced Thematic Mapper Plus (ETM+) time series imagery. The second part involved the computation and analysis of forest fragmentation metrics. For this portion of the study, fragmentation statistics were analyzed, and images were developed to depict forest fragmentation patterns and trends. Results revealed that there was a net loss of 7.8% in forest coverage, dropping from 66.8% in 1988 to 59.0% in 2005, primarily caused by agricultural expansion and poor forest management practices. An acceleration of forest fragmentation was also witnessed during the time intervals, which was evidenced by a decreasing trend in interior forest (57.2% in 1988, 55.0% in 1996 and 54.8% in 2005 respectively) coupled with the scales of the selected geospatial metrics. Continued forest loss and fragmentation are closely correlated with the existing political, educational, institutional and economic processes of contemporary China. To unlock the developmental potentials of the collective forests and to effectively mitigate the rate of forest loss and fragmentation, reforms of forest tenure and ecological immigration practices are recognized as a prospective alternative. The produced fragmentation maps further illustrates the importance of assessing landscape change history, especially the spatiotemporal patterns of forest fragments, when developing landscape level plans for biodiversity

  6. HYDROGEOLOGIC CASE STUDIE(PRESENTATION FOR MNA WORKSHOP)

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  7. GPM GROUND VALIDATION GCPEX SNOW MICROPHYSICS CASE STUDY V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The GPM Ground Validation GCPEX Snow Microphysics Case Study characterizes the 3-D microphysical evolution and distribution of snow in context of the thermodynamic...

  8. Teaching Case: Enterprise Architecture Specification Case Study

    Science.gov (United States)

    Steenkamp, Annette Lerine; Alawdah, Amal; Almasri, Osama; Gai, Keke; Khattab, Nidal; Swaby, Carval; Abaas, Ramy

    2013-01-01

    A graduate course in enterprise architecture had a team project component in which a real-world business case, provided by an industry sponsor, formed the basis of the project charter and the architecture statement of work. The paper aims to share the team project experience on developing the architecture specifications based on the business case…

  9. Theory Testing Using Case Studies

    DEFF Research Database (Denmark)

    Sørensen, Pernille Dissing; Løkke, Ann-Kristina

    2006-01-01

    design. Finally, we discuss the epistemological logic, i.e., the value to larger research programmes, of such studies and, following Lakatos, conclude that the value of theory-testing case studies lies beyond naïve falsification and in their contribution to developing research programmes in a progressive...

  10. Case Study of 'moral injury' : Format Dutch Case Studies Project

    NARCIS (Netherlands)

    Korver, Sjaak; Walton, Martin N.; van Loenen, Guus

    2017-01-01

    The case study ‘Moral Injury’ traces care provided by a chaplain in a mental health institution to a former military marksman named Hans. Hans was in care at a specialized unit for military veterans with traumas. He sought contact with a chaplain “to set things right with God” and wanted the

  11. Clinical and genetic characterization of six cases with complete ...

    Indian Academy of Sciences (India)

    JING HE

    2017-08-31

    Aug 31, 2017 ... The molecular study of the AR gene facilitated the understanding of the mechanism of CAIS and provided the genetic ... recessive genetic disease, which is characterized by par- .... the interaction of AR protein and androgenic hormone. .... in a brazilian cohort: Five novel mutations in the androgen receptor ...

  12. Neonatal appendicitis: a survival case study

    Directory of Open Access Journals (Sweden)

    Izabela Linha Secco

    Full Text Available ABSTRACT Objective: To report a case of neonatal appendicitis in a children’s hospital in southern Brazil, demonstrating the impact on neonatal survival. Method: Case study with data collection from medical records, approved by the Institution and Ethics Committee for Research with Human Beings. Results: The clinical picture is initially characterized by food intolerance, evolving to hypoactivity, alteration of vital signs and septicemia due to intestinal perforation. Management is exclusively surgical, since no case described in the literature was diagnosed preoperatively and the findings usually point to acute abdomen. Conclusion: A focused clinical surveillance should be established when the infant presents peritoneal irritation. Follow-up of the evolution and the worsening of the symptoms by nurses, as part of the care team in partnership with the medical team, enables an early surgical intervention, thereby avoiding complications such as septicemia and death.

  13. eCompetence Case Studies

    DEFF Research Database (Denmark)

    Jensen, Helle Bækkelund

    2006-01-01

    In this paper we present some details of the processes undertaken in the European eCompetence Initiative. We present two illustrative and representative case studies. The research aims to identify and understand patterns of individual and organisational eCompetence approaches.......In this paper we present some details of the processes undertaken in the European eCompetence Initiative. We present two illustrative and representative case studies. The research aims to identify and understand patterns of individual and organisational eCompetence approaches....

  14. Case Study on Logistics Performance

    Directory of Open Access Journals (Sweden)

    Shahryar Sorooshian

    2013-05-01

    Full Text Available The paper presents research carried out at a medium‐size manufacturing organization in east Asia. The study tries to highlight the importance of supply chain management; specifically, our aim for this study is to understand logistics and performance measurement in the logistics and supply chain, and we include a theoretical discussion of online data collected and a case study of the logistic performance of a real organization. The study also examines the performance of the selected company, identifies the problems and provides recommendations for improvements. This study can be a guide for business advisers and those interested in analysing company performance, especially from a logistics viewpoint. We also suggest the methodology of this case study for those who want to have a better understanding of a business environment before starting their own business, or for benchmarking practice during strategic planning.

  15. BioFleet case studies

    International Nuclear Information System (INIS)

    2007-01-01

    These six case studies examined the use of different biodiesel blends as fuel supply sources for businesses in British Columbia (BC). In the first case study, 6 municipalities participated in a pilot program designed to compare the performance of biodiesel and diesel fuels. Each municipality operated 2 base vehicles running on conventional diesel along with 2 similar vehicles which used biodiesel. Real time emissions tests and analyses of the vehicles using biodiesel were also conducted by 2 of the participating municipalities. All municipalities participating in the study agreed to purchase significant volumes of biodiesel. The second case study described a pilot study conducted by the City of Vancouver's equipment services branch in 2004. As a result of the study, the city now has over 530 types of equipment that use biodiesel. The third case study described a program designed by TSI Terminals in Vancouver to assess the emission reduction impact of using biodiesel at its port facility. Six different pieces of equipment were used to confirm that biodiesel could be used throughout the terminal. Test results confirmed that biodiesel blends could be used to reduce emissions. Overall emissions were reduced by 30 per cent. The fourth case study described a waste renderer that used a fleet of 36 trucks to deliver raw products to its plants. The company made the decision to use only biodiesel for its entire fleet of trucks. Since July 2005, the company has logged over 1.7 million km using biodiesel blends. The fifth case study described a salmon hatchery that switched from diesel to biodiesel in order to reduce emissions. The biodiesel blends are used to fuel the hatchery's 2 diesel generators. The hatchery has reduced emissions of greenhouse gases (GHGs) by an estimated 1800 tonnes annually. The sixth case study described how the Township of Langley has started using biodiesel for its entire fleet of of approximately 250 pieces of equipment. The township has not

  16. Case Studies in Sports Nutrition.

    Science.gov (United States)

    Clark, Nancy

    1988-01-01

    This article presents case studies of two athletes who wanted to affect a change in their body weight in order to enhance athletic performance. Each athlete's problem and the nutrition approach used to solve it are discussed. Caloric values of fast foods are listed. (JL)

  17. Shea case study Burkina Faso

    NARCIS (Netherlands)

    S. Drost (Sarah); J.C.A.C. van Wijk (Jeroen); S.R. Vellema (Sietze)

    2012-01-01

    textabstractThis shea case study is part of a larger Partnerships Resource Centre (PrC) project elaborated in tandem with two Dutch non-governmental organisations (NGOs); ICCO and Oxfam Novib. The endeavour of this ‘action research’ project is to combine the expert knowledge of development

  18. The reflexive case study method

    DEFF Research Database (Denmark)

    Rittenhofer, Iris

    2015-01-01

    This paper extends the international business research on small to medium-sized enterprises (SME) at the nexus of globalization. Based on a conceptual synthesis across disciplines and theoretical perspectives, it offers management research a reflexive method for case study research of postnational...

  19. Geostatistics for radiological characterization: overview and application cases

    International Nuclear Information System (INIS)

    Desnoyers, Yvon

    2016-01-01

    The objective of radiological characterization is to find a suitable balance between gathering data (constrained by cost, deadlines, accessibility or radiation) and managing the issues (waste volumes, levels of activity or exposure). It is necessary to have enough information to have confidence in the results without multiplying useless data. Geo-statistics processing of data considers all available pieces of information: historical data, non-destructive measurements and laboratory analyses of samples. The spatial structure modelling is then used to produce maps and to estimate the extent of radioactive contamination (surface and depth). Quantifications of local and global uncertainties are powerful decision-making tools for better management of remediation projects at contaminated sites, and for decontamination and dismantling projects at nuclear facilities. They can be used to identify hot spots, estimate contamination of surfaces and volumes, classify radioactive waste according to thresholds, estimate source terms, and so on. The spatial structure of radioactive contamination makes the optimization of sampling (number and position of data points) particularly important. Geo-statistics methodology can help determine the initial mesh size and reduce estimation uncertainties. Several show cases are presented to illustrate why and how geo-statistics can be applied to a range of radiological characterization where investigated units can represent very small areas (a few m 2 or a few m 3 ) or very large sites (at a country scale). The focus is then put on experience gained over years in the use of geo-statistics and sampling optimization. (author)

  20. Characterization of Staphylococcus simulans strains isolated from cases of bovine mastitis

    DEFF Research Database (Denmark)

    Aarestrup, Frank Møller; Larsen, H. D.; Jensen, N. E.

    1999-01-01

    This study was conducted to characterize Staphylococcus simulans isolated from cases of bovine mastitis. A total of 134 isolates of S. simulans selected from 80 quarters from 61 cows or heifers in 37 different herds were characterized by EcoRI ribotyping. From 22 quarters two to seven consecutive......, where 76 paired or multiple isolates were at disposal, the same ribotype was constantly found in the same quarter. This study showed that S. simulans causing bovine mastitis could be divided into relatively large number of different types, but that two types predominated. More than one type could...

  1. Institutional total energy case studies

    Energy Technology Data Exchange (ETDEWEB)

    Wulfinghoff, D.

    1979-07-01

    Profiles of three total energy systems in institutional settings are provided in this report. The plants are those of Franciscan Hospital, a 384-bed facility in Rock Island, Illinois; Franklin Foundation Hospital, a 100-bed hospital in Franklin, Louisiana; and the North American Air Defense Command Cheyenne Mountain Complex, a military installation near Colorado Springs, Colorado. The case studies include descriptions of plant components and configurations, operation and maintenance procedures, reliability, relationships to public utilities, staffing, economic efficiency, and factors contributing to success.

  2. Stochastic efficiency: five case studies

    International Nuclear Information System (INIS)

    Proesmans, Karel; Broeck, Christian Van den

    2015-01-01

    Stochastic efficiency is evaluated in five case studies: driven Brownian motion, effusion with a thermo-chemical and thermo-velocity gradient, a quantum dot and a model for information to work conversion. The salient features of stochastic efficiency, including the maximum of the large deviation function at the reversible efficiency, are reproduced. The approach to and extrapolation into the asymptotic time regime are documented. (paper)

  3. Case Study: Guidelines for Producing Videos to Accompany Flipped Cases

    Science.gov (United States)

    Prud'homme-Généreux, Annie; Schiller, Nancy A.; Wild, John H.; Herreid, Clyde Freeman

    2017-01-01

    Three years ago, the "National Center for Case Study Teaching in Science" (NCCSTS) was inspired to merge the case study and flipped classroom approaches. The resulting project aimed to create the materials required to teach a flipped course in introductory biology by assigning videos as homework and case studies in the classroom. Three…

  4. CAREM X INPRO case study

    International Nuclear Information System (INIS)

    Florido, P.C.; Brasnarof, D.; Delmastro, D.; Azpitarte, O.E.

    2004-01-01

    In order to assess and compare the performance of innovative nuclear energy systems INPRO has defined a set of basic principles, user requirements and criteria to be met in different areas (economics, sustainability and environment, safety, waste management and proliferation). This paper illustrates the use of INPRO methodology to a particular reactor system. Argentina is performing CAREM X Nuclear System Case Study based on CAREM nuclear reactor and Once Through Fuel Cycle, using SIGMA for enriched uranium production, and a deep geological repository for final disposal of high level waste after surface intermediate storage in horizontal natural convection silos, to verify INPRO (International Project on Innovative Nuclear Reactors and Fuel Cycles) methodology. 6 aspects have been considered: 1) enrichment based on Sigma enrichment plant (gas diffusion technology), 2) conversion to UO 2 , 3) fuel manufacturing, 4) CAREM-300 based reactor technology, 5) intermediate spent fuel storage, and 6) deep geological repository of spent fuels. Projections show that developing countries could play a crucial role in the deployment of nuclear energy, in the next fifty years. This case study will be highly useful for checking INPRO methodology for this scenario. In this paper, the preliminary findings of the Case Study are presented, including proposals to improve the INPRO methodology

  5. A case study of Impetigo

    Directory of Open Access Journals (Sweden)

    Mansouri P

    1993-05-01

    Full Text Available This is a report of a case study on 234 patients with impetigo who referred to Razi Dermatology Hospital from April to November, 1989. Treatment was started immediately after obtaining direct smear and performing culture and antibiotic sensitivity test. The most common organism responsible for impetigo was the coagulase-positive staphylococcus (71%. In 13.7% of the cases, the coagulase-negative staphylococcus was grown on culture media, but none of the cultures showed streptococcus as the main organism. Treatment was started with oral penicillin V, oral erythromycin, benzathine penicillin G injection, oral cephalexin, and topical fuccidin. Clinical and bacteriological evaluation after 3-7 days showed that it is preferable to use oral cephalexin instead of other protocols such as oral erythromycin, which has previously been the drug of choice for impetigo. In addition, topical fuccidin with a 75% curative rate was the first drug for treatment, with the same effect as the oral cephalexin

  6. MULTIPLE PERSONALITY: CASE REPORT STUDY

    Directory of Open Access Journals (Sweden)

    Miloš Židanik

    2004-07-01

    Full Text Available Background. Multiple personality disorder is characterised by splited individual ego-states and splited professional community arguing whether this disorder actually exists or not.Methods. In this case report study a supportive psychodynamic psychotherapy of a patient with multiple personality disorder is presented, that lasted for 4.5 years and resulted in ego-reintegration.Conclusions. The spliting between different ego-states is powered by unneutralised aggression with the possibility of hetero- and autoaggressive behaviour. Therefore the patient in the analytically oriented psychotherapeutic process is at high risk and a safe therapeutic (e. g. in-patient setting has to be provided.

  7. Overview of the Case Studies

    DEFF Research Database (Denmark)

    Cameron, Ian; Gani, Rafiqul

    2011-01-01

    A series of case studies are used to illustrate many of the underlying modelling principles within the book. To facilitate this, the ICAS-MoT modelling tool has been used. A wide range of application areas have been chosen to ensure that the principal concepts of effective and efficient modelling...... are exercised. Conceptual frameworks for single and multiscale problems are given and explained. The importance of the steps is also explained, through annotated schematic diagrams. The important issues around workflow and data flow are given in diagrammatic form....

  8. Hospital Waste Management - Case Study

    Directory of Open Access Journals (Sweden)

    Beatriz Edra

    2017-07-01

    Full Text Available The importance of waste management in hospitals is indisputable in preserving the environment and protecting public health, but management models are rarely discussed. This study presents the legal and conceptual frameworks of good waste management practices applicable to hospitals and associated indicators. As a case study, the overall performance of Hospital Centre of São João, in Porto, was analysed based on published reports. Data on the production of waste in their different typologies were collected from 2010 to 2016, enabling a correlation of the waste production with the kg/bed/day indicator. The aim of this study was to gather data and discuss trends in a real scenario of evolution over a six-year period in order to contribute to a future research proposal on indicators that can be used as reference for benchmarking the construction of methodological guides for hospital waste management.

  9. Case Study: Camptocormia, a Rare Conversion Disorder.

    Science.gov (United States)

    Rajmohan, Velayudhan; Thomas, Biju; Sreekumar, Kumaran

    2004-01-01

    Camptocormia is a condition characterized by severe frontal flexion of the spinal cord and knees, with passive drooping of both arms. It occurs as a form of conversion disorder. Some cases are associated with behavioral problems. A case of camptocormia of 2-year duration in a south Indian adolescent girl with oppositional defiant disorder and…

  10. Qualitative Case Study Research as Empirical Inquiry

    Science.gov (United States)

    Ellinger, Andrea D.; McWhorter, Rochell

    2016-01-01

    This article introduces the concept of qualitative case study research as empirical inquiry. It defines and distinguishes what a case study is, the purposes, intentions, and types of case studies. It then describes how to determine if a qualitative case study is the preferred approach for conducting research. It overviews the essential steps in…

  11. A parathyroid scintigraphy case study

    International Nuclear Information System (INIS)

    O'Leary, Desiree

    2005-01-01

    Background: There has been much debate concerning the most suitable protocol for parathyroid scintigraphy; the merits of various radiopharmaceuticals versus the correct imaging protocol to visualise both ectopic and anatomically placed adenomas against the various equipment choices have been debated. Aim: To demonstrate, through the use of a case study, the necessity of changing imaging protocols for parathyroid scintigraphy where a definitive imaging diagnosis is absent in the face of strong clinical suspicion. Method: Use is made of Tc99mMIBI, full field chest scintigraphy, a clearly defined imaging protocol and SPECT imaging to locate ectopic parathyroid tissue in a female patient with significant symptoms of parathyroid hyperfunction. Results: A single hyperfunctioning adenoma is located in the pre-carinal area of the mediastinum. Using a radioguided surgical technique the hyperfunctioning tissue is excised and confirmed by histopathology. Conclusion: Whilst a dramatic reduction in patient symptoms was not seen immediately in this patient, the symptoms of the illness have been subsiding since January 2003. This case study demonstrates the necessity of changing imaging protocols for parathyroid scintigraphy where a definitive imaging diagnosis is absent in the face of strong clinical suspicion

  12. Using Correspondence Analysis in Multiple Case Studies

    NARCIS (Netherlands)

    Kienstra, Natascha; van der Heijden, Peter G.M.

    2015-01-01

    In qualitative research of multiple case studies, Miles and Huberman proposed to summarize the separate cases in a so-called meta-matrix that consists of cases by variables. Yin discusses cross-case synthesis to study this matrix. We propose correspondence analysis (CA) as a useful tool to study

  13. Using correspondence analysis in multiple case studies

    NARCIS (Netherlands)

    Kienstra, N.H.H.; van der Heijden, P.G.M.

    2015-01-01

    In qualitative research of multiple case studies, Miles and Huberman proposed to summarize the separate cases in a so-called meta-matrix that consists of cases by variables. Yin discusses cross-case synthesis to study this matrix. We propose correspondence analysis (CA) as a useful tool to study

  14. Site characterization studies in the NWTS program

    International Nuclear Information System (INIS)

    Shipler, D.; Evans, G.

    1980-01-01

    The US Department of Energy (DOE) has the responsibility to identify sites and construct and operate facilities for the storage or isolation of spent fuel and/or reprocessing radioactive wastes from commercial nuclear power plants. The National Waste Terminal Storage (NWTS) Program has been initiated by the DOE to develop the technology and demonstrate the feasibility of burial and isolation of high level radioactive waste in deep geologic formations. The NTWS Program plan which sets forth the criteria, procedures, and other considerations required to characterize and select a site in a comprehensive stepwise manner is discussed. The plan is not specific to any given geologic medium but serves as a guide for site selection in any geohydrologic system deemed appropriate for consideration for a deep geologic repository. The plan will be used by all NWTS Project Offices in the conduct of their site characterization program. The plan will be updated, as warranted, to reflect technology development, National policies, rulemakings by regulatory agencies, and other changing political, social, and institutional considerations. Site characterization begins with the identification of regions believed to have suitable geologic, hydrologic, and environmental characteristics for repository siting. This is followed by an iterative process of data collection and analysis to identify areas and locations which appear most suitable for further investigations. In addition, screening studies of the DOE's nuclear complexes has led to the selection of the Nevada Test Site and the Hanford Site for further characterization studies. The site characterization process results in a number of candidate sites from which a site will be selected and proposed to the NRC for licensing

  15. Case Study: A Picture Worth a Thousand Words? Making a Case for Video Case Studies

    Science.gov (United States)

    Pai, Aditi

    2014-01-01

    A picture, they say, is worth a thousand words. If a mere picture is worth a thousand words, how much more are "moving pictures" or videos worth? The author poses this not merely as a rhetorical question, but because she wishes to make a case for using videos in the traditional case study method. She recommends four main approaches of…

  16. Workplace characterizations in case of rail transport of radioactive materials

    International Nuclear Information System (INIS)

    Donadille, L.; Itie, C.; Lahaye, T.; Muller, H.; Bottolier-Depois, J.F.

    2005-01-01

    Full text: Radioactive fuel and wastes are frequently transported for storage and/or reprocessing purposes. The main part of this transport is generally done by train. Before, during and after the journey, operators and drivers, who work directly in contact with and in the vicinity of the wagons, are exposed to external irradiations due to the radioactive materials that are confined inside the containers. In order to evaluate the dose that its personnel is liable to receive during such transports, the French National Railway Company (SNCF) has requested to the Institute of Radiological Protection and Nuclear Safety (IRSN) a series of workplaces characterizations for convoys of different types, that are considered to be representative of all types of possible transports. Each one is associated to a given radioactive material (low and medium activity wastes, new and used fuel, MOX, uranium fluoride, etc... ), involving photon or mixed neutron-photon fields. This measurement campaign has started in May 2004 and by the end of 2004 at least four types of radioactive convoys will have been investigated (three have already been measured). By using survey meters and spectrometers, the study consists in measuring the external exposure for different stages of the work that is done beside the wagons (for example coupling / decoupling two wagons, or checking the brakes) and inside the locomotive (driving). For each one of these workplaces, the exposure is estimated in terms of the ambient dose equivalent H*(10) by summing the dose all along the different phases carried out by the operator. In addition, a dosimetric characterization of each convoy is made by performing measurements along the wagons and spectrometric information about the photon and/or neutron fields are collected. This study provides helpful data to predict the dose that the operators are liable to integrate over long periods, typically one year. (author)

  17. Case studies in ultrasonic testing

    International Nuclear Information System (INIS)

    Prasad, V.; Satheesh, C.; Varde, P.V.

    2015-01-01

    Ultrasonic testing is widely used Non Destructive Testing (NDT) method and forms the essential part of In-service inspection programme of nuclear reactors. Main application of ultrasonic testing is for volumetric scanning of weld joints followed by thickness gauging of pipelines and pressure vessels. Research reactor Dhruva has completed the first In Service Inspection programme in which about 325 weld joints have been volumetrically scanned, in addition to thickness gauging of 300 meters of pipe lines of various sizes and about 24 nos of pressure vessels. Ultrasonic testing is also used for level measurements, distance measurements and cleaning and decontamination of tools. Two case studies are brought out in this paper in which ultrasonic testing is used successfully for identification of butterfly valve opening status and extent of choking in pipe lines in Dhruva reactor systems

  18. STS Case Study Development Support

    Science.gov (United States)

    Rosa de Jesus, Dan A.; Johnson, Grace K.

    2013-01-01

    The Shuttle Case Study Collection (SCSC) has been developed using lessons learned documented by NASA engineers, analysts, and contractors. The SCSC provides educators with a new tool to teach real-world engineering processes with the goal of providing unique educational materials that enhance critical thinking, decision-making and problem-solving skills. During this third phase of the project, responsibilities included: the revision of the Hyper Text Markup Language (HTML) source code to ensure all pages follow World Wide Web Consortium (W3C) standards, and the addition and edition of website content, including text, documents, and images. Basic HTML knowledge was required, as was basic knowledge of photo editing software, and training to learn how to use NASA's Content Management System for website design. The outcome of this project was its release to the public.

  19. A case study of strategic planning IFB

    Directory of Open Access Journals (Sweden)

    Pedro Henrique Rodrigues de Camargo Dias

    2018-03-01

    Full Text Available The purpose of this article is to identify and characterize the initial stage of the IFB strategic planning, based on the perception of top management and planning team. The case study adopts a qualitative approach supported by bibliographic research techniques, to build a theoretical foundation, allied to the semistructure interview for later, application of the content analysis. As a result, we can identify that the institution opted to first define the strategic references, based on the construction of the mission, vision and values, and later, analysis of the organizational diagnosis, based on the Balanced Scorecard methodology. It was verified that the tool of strategic planning and its use are points that need to be better understood by the managers and technical planning team. The predominant characteristics of strategic planning are composed of a programmatic tool for projecting medium and long term goals and actions, of legal compliance, as it integrates and operationalizes the Institutional Development Plan (PDI.

  20. Characterizing the malaria rural-to-urban transmission interface: The importance of reactive case detection.

    Directory of Open Access Journals (Sweden)

    Karen Molina Gómez

    2017-07-01

    Full Text Available Reported urban malaria cases are increasing in Latin America, however, evidence of such trend remains insufficient. Here, we propose an integrated approach that allows characterizing malaria transmission at the rural-to-urban interface by combining epidemiological, entomological, and parasite genotyping methods.A descriptive study that combines active (ACD, passive (PCD, and reactive (RCD case detection was performed in urban and peri-urban neighborhoods of Quibdó, Colombia. Heads of households were interviewed and epidemiological surveys were conducted to assess malaria prevalence and identify potential risk factors. Sixteen primary cases, eight by ACD and eight by PCD were recruited for RCD. Using the RCD strategy, prevalence of 1% by microscopy (6/604 and 9% by quantitative polymerase chain reaction (qPCR (52/604 were found. A total of 73 houses and 289 volunteers were screened leading to 41 secondary cases, all of them in peri-urban settings (14% prevalence. Most secondary cases were genetically distinct from primary cases indicating that there were independent occurrences. Plasmodium vivax was the predominant species (76.3%, 71/93, most of them being asymptomatic (46/71. Urban and peri-urban neighborhoods had significant sociodemographic differences. Twenty-four potential breeding sites were identified, all in peri-urban areas. The predominant vectors for 1,305 adults were Anopheles nuneztovari (56,2% and An. Darlingi (42,5%. One An. nuneztovari specimen was confirmed naturally infected with P. falciparum by ELISA.This study found no evidence supporting the existence of urban malaria transmission in Quibdó. RCD strategy was more efficient for identifying malaria cases than ACD alone in areas where malaria transmission is variable and unstable. Incorporating parasite genotyping allows discovering hidden patterns of malaria transmission that cannot be detected otherwise. We propose to use the term "focal case" for those primary cases that

  1. Five Misunderstandings About Case-Study Research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    2006-01-01

    This article examines five common misunderstandings about case-study research: (a) theoretical knowledge is more valuable than practical knowledge; (b) one cannot generalize from a single case, therefore, the single-case study cannot contribute to scientific development; (c) the case study is most...... useful for generating hypotheses, whereas other methods are more suitable for hypotheses testing and theory building; (d) the case study contains a bias toward verification; and (e) it is often difficult to summarize specific case studies. This article explains and corrects these misunderstandings one...

  2. Experimental study of canvas characterization for paintings

    Science.gov (United States)

    Cornelis, Bruno; Dooms, Ann; Munteanu, Adrian; Cornelis, Jan; Schelkens, Peter

    2010-02-01

    The work described here fits in the context of a larger project on the objective and relevant characterization of paintings and painting canvas through the analysis of multimodal digital images. We captured, amongst others, X-ray images of different canvas types, characterized by a variety of textures and weave patterns (fine and rougher texture; single thread and multiple threads per weave), including raw canvas as well as canvas processed with different primers. In this paper, we study how to characterize the canvas by extracting global features such as average thread width, average distance between successive threads (i.e. thread density) and the spatial distribution of primers. These features are then used to construct a generic model of the canvas structure. Secondly, we investigate whether we can identify different pieces of canvas coming from the same bolt. This is an important element for dating, authentication and identification of restorations. Both the global characteristics mentioned earlier and some local properties (such as deviations from the average pattern model) are used to compare the "fingerprint" of different pieces of cloth coming from the same or different bolts.

  3. [Case-non case studies: Principles, methods, bias and interpretation].

    Science.gov (United States)

    Faillie, Jean-Luc

    2017-10-31

    Case-non case studies belongs to the methods assessing drug safety by analyzing the disproportionality of notifications of adverse drug reactions in pharmacovigilance databases. Used for the first time in the 1980s, the last few decades have seen a significant increase in the use of this design. The principle of the case-non case study is to compare drug exposure in cases of a studied adverse reaction with that of cases of other reported adverse reactions and called "non cases". Results are presented in the form of a reporting odds ratio (ROR), the interpretation of which makes it possible to identify drug safety signals. This article describes the principle of the case-non case study, the method of calculating the ROR and its confidence interval, the different modalities of analysis and how to interpret its results with regard to the advantages and limitations of this design. Copyright © 2017 Société française de pharmacologie et de thérapeutique. Published by Elsevier Masson SAS. All rights reserved.

  4. Concentrated photovoltaics, a case study

    Directory of Open Access Journals (Sweden)

    Antonini Piergiorgio

    2014-01-01

    Full Text Available Concentrated Photovoltaics (CPV, once a niche technology, has now reached the maturity and reliability for large scale power generation. Especially in regions where temperatures are very high, the use of high efficiency triple junction solar cells with concentrating optics allows stable energy yield. Thus CPV can be seen as complementary and not in concurrence with silicon photovoltaics. The state of the art, the advantages and limitations of this technology will be shown. Among the main advantages of CPV is the possibility of a much higher energy supply, when compared to silicon photovoltaics, both comparing CPV and silicon with same area or the same installed power. The use of recycled and recyclable materials allows a more environmentally friendly production. The possibility to couple CPV with desalination facilities, energy storage will be analysed. As an example a case study of a CPV installation in Northern Italy is discussed. Here the use of mature technologies, derived from automotive and lighting sectors resulted in a simple and efficient module.

  5. Case Studies of Environmental Visualization

    Directory of Open Access Journals (Sweden)

    Panagiotis Patlakas

    2017-09-01

    Full Text Available The performance gap between simulation and reality has been identified as a major challenge to achieving sustainability in the Built Environment. While Post-Occupancy Evaluation (POE surveys are an integral part of better understanding building performance, and thus addressing this issue, the importance of POE remains relatively unacknowledged within the wider Built Environment community. A possible reason that has been highlighted is that POE survey data is not easily understood and utilizable by non-expert stakeholders, including designers. A potential method by which to address this is the visualization method, which has well established benefits for communication of big datasets. This paper presents two case studies where EnViz (short for “Environmental Visualization”, a prototype software application developed for research purposes, was utilized and its effectiveness tested via a range of analysis tasks. The results are discussed and compared with those of previous work that utilized variations of the methods presented here. The paper concludes by presenting the lessons drawn from the five-year period of EnViz, emphasizing the potential of environmental visualization for decision support in environmental design and engineering for the built environment, and suggests directions for future development.

  6. Catalog of NASA-Related Case Studies

    Data.gov (United States)

    National Aeronautics and Space Administration — The OCKO has developed over 50 case studies to enhance learning at workshops, training, retreats and conferences. Case studies make mission knowledge attractive and...

  7. Characterization of wastes and their recycling potentials; A case ...

    African Journals Online (AJOL)

    MICHAEL HORSFALL

    Key words: Solid waste, waste characterization, recycling potentials, waste scavengers. ABSTRACT: Wastes ... Waste management is the collection, transportation, processing ... wastes generated by household, commercial activities or other ...

  8. a South African case study

    African Journals Online (AJOL)

    User

    learn different algorithms to solve problems, but in many cases cannot solve .... centre of Piaget‟s work is a fundamental cognitive process, which he termed ..... concept definition of continuity in calculus through collaborative instructional ...

  9. Case Study: The Chemistry of Cocaine

    Science.gov (United States)

    Dewprashad, Brahmadeo

    2011-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's case study focuses on the chemistry of cocaine to teach a number of core concepts in organic chemistry. It also requires that students read and analyze an original research paper on…

  10. Writing case studies in information systems research

    NARCIS (Netherlands)

    van der Blonk, H.C.

    Case study research can be reported in different ways. This paper explores the various ways in which researchers may choose to write down their case studies and then introduces a subsequent typology of writing case studies. The typology is based on a 2 x 2 matrix, resulting in four forms of writing

  11. Summary of case studies for cooperation mechanisms

    DEFF Research Database (Denmark)

    Longa, Francesco Dalla; Klinge Jacobsen, Henrik; Hansen, Lise-Lotte Pade

    2012-01-01

    This document is a summary report highlighting the main aspect analyzed in the RES4LESS case studies. The document starts with an introductory chapter where the background that led to the selection of the case studies is outlined. In the following three chapters the case studies are presented, hi...

  12. Lymphedema during pregnancy - case study

    Directory of Open Access Journals (Sweden)

    Katarzyna Korabiusz

    2017-06-01

    Full Text Available Pregnancy is a period when woman’s body undergoes a lot of changes in her hormonal balance, lymphatic system, musculoskeletal system and cardiovascular system. As a result of disorders in defense mechanisms, a significant amount of liquid accumulates in spaces between tissues. A clinical manifestation of this condition is swelling located around ankles and lower legs. Sedentary lifestyle, unhealthy eating habits, excessive weight and pregnancy are also well known causes of lymphatic swelling. Comprehensive anti-swelling therapy that is used in treating lymphatic swelling in pregnant patients includes: patients’ education, manual lymphatic drainage, kinesitherapy, multilayer bandaging, skin care, drainage positions and kinesiotaping. Dissertation’s objective: Dissertation’s objective is to evaluate implementation of manual lymphatic drainage and anti-swelling kinesiotaping in pregnant woman with lymphatic swelling of lower legs. Research methods: Research methods were collected basing on: interview with a patient, medical documentation analysis and physical examination conduced before and after therapy. Research was conducted between 34th and 36th week of pregnancy. Case study: 38 year old patient in her fourth singleton pregnancy. Two prior pregnancies in 2009 and 2010 were delivered with C-section and one missed abortion in 2015 occurred. During this pregnancy patient gained over 30kg. She was diagnosed with lymphatic swelling of metatarsus, lower legs and ankles in 34th week of pregnancy. Lymphatic drainage of lower limbs and anti-swelling kinesiotaping was implemented. Results: After two weeks of therapy decrease in swelling was observed in left lower limb: in metatarsus by 8cm, in ankles by 9cm and in lower legs by 6cm. In right lower limb swelling decreased accordingly by 7cm, 10cm and 5cm. Conclusion: Anti-swelling lymphatic drainage, kinesiotherapy and kinesiotaping are effective physiotherapy methods used in treating lymphedema

  13. Methodology for characterizing the environmental impacts of hydroelectric generating stations : a case study of Farmer Rapids; Methodologie d'acquisition des connaissances pour la gestion environnmentale de centrales hydroelectriques : cas de la centrale Rapides-Farmers, rivieres Gatineau

    Energy Technology Data Exchange (ETDEWEB)

    Lemieux, C.; Renaud, S.; Begin, P.; Belzile, L. [Genivar SEC, Quebec, PQ (Canada); Caumartin, J. [Hydro-Quebec, Montreal, PQ (Canada)

    2006-07-01

    This paper described a novel methodology used to characterize the downstream section of a generating station that was not navigable by boat. The method was used as part of a fish habitat characterization study conducted in the Farmers Rapids area of Quebec. The purpose of the study was to identify the discharges and water levels needed to preserve fish habitats in the region. Initially, experimental fishing was undertaken to locate, validate and characterize fish habitats. Habitat models were then developed using a microhabitat modelling method to establish pertinent discharges and water levels. In order to model areas that were not navigable by boat, discharges released by the generating station were reduced to a minimum to temporarily decrease water levels and expose the river. High definition aerial photography and topographic mapping was conducted. The information obtained from the 2 procedures was then used to describe and map the riverbed substrate as well as the bathymetry and aquatic habitats. A 2D hydrodynamic model was then used to simulate water flows in the area at various discharges. The results of the hydrodynamic models and the habitat models were then used to establish appropriate discharges for optimal fish habitats.

  14. SPHENOCHOANAL POLYP: A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Gaurav

    2015-09-01

    Full Text Available Sphenochoanal polyp is a rare clinical occurrence as compared to the much common antro - choanal polyp. It originates from the sphenoid sinus and extends into the choana via the sphenoid ostium. We present a case of spheno - choanal polyp and its clinical features and surgical management is discussed. Our aim in this case was to properly d elineate the origin of the polyp and differentiate it from other lesions such as the antro - choanal polyp and meningocele, followed by meticulous endoscopic excision of the polyp

  15. Minecraft as a Creative Tool: A Case Study

    Science.gov (United States)

    Cipollone, Maria; Schifter, Catherine C.; Moffat, Rick A.

    2014-01-01

    Many scholars are enthusiastic about the potential learning opportunities present in the sandbox-style gaming environment, Minecraft. In the following case study, the authors explored the use of Minecraft in a high school literature class and the presentation of characterization and plot in three student-made machinima, or films made in the game…

  16. Using Case Studies to Enrich Field Experience.

    Science.gov (United States)

    Florio-Ruane, Susan; Clark, Christopher M.

    1990-01-01

    This paper discusses the use of field experience in teacher education and how it can be augmented by phenomenological case studies. It summarizes a particular case study involving three teacher education classes, noting that reflective analysis of cases can prepare students to observe in the field. (SM)

  17. Transanal rectopexy - twelve case studies

    Directory of Open Access Journals (Sweden)

    Rubens Henrique Oleques Fernandes

    2012-06-01

    Full Text Available OBJECTIVES: This study analyzed the results of transanal rectopexy and showed the benefits of this surgical technique. METHOD: Twelve patients were submitted to rectopexy between 1997 and 2011. The surgical technique used was transanal rectopexy, where the mesorectum was fixed to the sacrum with nonabsorbable suture. Three patients had been submitted to previous surgery, two by the Delorme technique and one by the Thiersch technique. RESULTS: Postoperative hospital stay ranged from 1 to 4 days. One patient (8.3% had intraoperative hematoma, which was treated with local compression and antibiotics. One patient (8.3% had residual mucosal prolapse, which was resected. Prolapse recurrence was seen in one case (8.3%. Improved incontinence occurred in 75% of patients and one patient reported obstructed evacuation in the first month after surgery. No death occurred. CONCLUSION: Transanal rectopexy is a simple, low cost technique, which has shown good efficacy in rectal prolapse control.OBJETIVO: O presente estudo analisou os resultados da retopexia pela via transanal e expôs os benefícios desta técnica cirúrgica. MÉTODO: Doze pacientes com prolapso foram operados no período de 1997 a 2011. A técnica cirúrgica usada foi a retopexia transanal, onde o mesorreto foi fixado ao sacro com fio inabsorvível. Três pacientes tinham cirurgia prévia, dois pela técnica de Delorme e um pela técnica de Thiersch. RESULTADOS: A permanência hospitalar pós-operatória variou de 1- 4 dias. Uma paciente (8,3% apresentou hematoma transoperatório que foi tratado com compressão local e antibioticoterapia. Um paciente apresentou prolapso mucoso residual (8,3%, que foi ressecado. Houve recidiva da procidência em um caso (8,3%. A melhora da incontinência ocorreu em 75% dos pacientes e uma paciente apresentou bloqueio evacuatório no primeiro mês após a cirurgia. Não houve mortalidade entre os pacientes operados. CONCLUSÃO: A retopexia transanal é uma t

  18. WP4 Case study Report

    DEFF Research Database (Denmark)

    Elle, Morten; van Gameren, Valentine; Pel, Bonno

    The INFORSE case consists of an analysis of the transnational network INFORSE (International Network for Sustainable Energy), the Danish local initiative VE and the Belgian local initiative APERe. All three are dealing with renewable energy and energy savings. The link between INFORSE and VE...

  19. Five misunderstandings about Case-study Research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...... useful for generating hypotheses, while other methods aremore suitable for hypotheses testing and theory building; (4) The case study contains a bias toward verification; and (5) It is often difficult to summarize specific case studies. The article explains and corrects these misunderstandings one by one...... and concludes with the Kuhnian insight that a scientific discipline without a large number of thoroughly executed case studies is a discipline without systematic production of exemplars, and that a discipline without  exemplars is an ineffective one. Social science may be strengthened by the execution of more...

  20. Five misunderstandings about case study research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    2004-01-01

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...... useful for generating hypotheses, while other methods aremore suitable for hypotheses testing and theory building; (4) The case study contains a bias toward verification; and (5) It is often difficult to summarize specific case studies. The article explains and corrects these misunderstandings one by one...... and concludes with the Kuhnian insight that a scientific discipline without a large number of thoroughly executed case studies is a discipline without systematic production of exemplars, and that a discipline without exemplars is an ineffective one. Social science may be strengthened by the execution of more...

  1. Drive Electric Vermont Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Fred [Energetics Incorporated, Columbia, MD (United States); Roberts, Dave [Vermont Energy Investment Corporation (VEIC), Burlington, VT (United States); Francfort, Jim [Idaho National Lab. (INL), Idaho Falls, ID (United States); White, Sera [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    Currently in the United States, the heavy majority of plug-in electric vehicle (PEV) sales have been in highly conducive, selected, metropolitan areas; opposed to more broad distribution across the country. The U.S. Department of Energy’s EV Everywhere Grand Challenge is looking carefully at the barriers and opportunities that exist to enable small and midsize communities to partake in the PEV market and benefit from the economic and environmental advantages of PEVs. In order to gain insight into these challenges and barriers, DOE selected a success story (i.e., Drive Electric Vermont) as the subject of this case study, as the state of Vermont is tied with Detroit, Michigan in having the highest percentage of 2014 (most recent complete data) PEV registrations for cold weather U.S. cities and has seen more than a sixfold increase in charging stations over the last three years. The overall objective of this case study was to use the lessons learned from Drive Electric Vermont to determine what activities are most effective at encouraging acquisitions of PEVs and deployment of charging infrastructure in small to midsize communities, prioritizing and sequencing their implementation, identifying robust means for extrapolation, and applying this understanding to other small to midsize communities across the nation. The Drive Electric Vermont Program was formed in 2012 with a goal of increasing the use of electrified transportation in Vermont through policy development, education and outreach, and infrastructure development. The Drive Electric Vermont Program can be broadly broken into four components: (1) strategic planning/leadership, (2) stakeholder/partnership development, (3) education and outreach, and (4) incentives. The early phases of the program focused heavily on strategic planning, and stakeholder and partnership development, followed by a transition to education and outreach activities, charging infrastructure development, and grant and incentive programs

  2. Creatine Transporter Deficiency: Screening of Males with Neurodevelopmental Disorders and Neurocognitive Characterization of a Case.

    Science.gov (United States)

    Thurm, Audrey; Himelstein, Daniel; DʼSouza, Precilla; Rennert, Owen; Jiang, Susanqi; Olatunji, Damilola; Longo, Nicola; Pasquali, Marzia; Swedo, Susan; Salomons, Gajja S; Carrillo, Nuria

    2016-05-01

    Creatine transporter deficiency (CTD) is an X-linked, neurometabolic disorder associated with intellectual disability that is characterized by brain creatine (Cr) deficiency and caused by mutations in SLC6A8, the Cr transporter 1 protein gene. CTD is identified by elevated urine creatine/creatinine (Cr/Crn) ratio or reduced Cr peak on brain magnetic resonance spectroscopy; the diagnosis is confirmed by decreased Cr uptake in cultured fibroblasts, and/or identification of a mutation in the SLC6A8 gene. Prevalence studies suggest this disorder may be underdiagnosed. We sought to identify cases from a well-characterized cohort of children diagnosed with neurodevelopmental disorders. Urine screening for CTD was performed on a cohort of 46 males with autism spectrum disorder (ASD) and 9 males with a history of non-ASD developmental delay (DD) classified with intellectual disability. We identified 1 patient with CTD in the cohort based on abnormal urine Cr/Crn, and confirmed the diagnosis by the identification of a novel frameshift mutation in the SLC6A8 gene. This patient presented without ASD but with intellectual disability, and was characterized by a nonspecific phenotype of early language delay and DD that persisted into moderate-to-severe intellectual disability, consistent with previous descriptions of CTD. Identification of patients with CTD is possible by measuring urine Cr and Crn levels and the current case adds to the growing literature of neurocognitive deficits associated with the disorder that affect cognition, language and behavior in childhood.

  3. Integrative health coaching: an organizational case study.

    Science.gov (United States)

    Wolever, Ruth Q; Caldwell, Karen L; Wakefield, Jessica P; Little, Kerry J; Gresko, Jeanne; Shaw, Andrea; Duda, Linda V; Kosey, Julie M; Gaudet, Tracy

    2011-01-01

    The aim of this study was to describe integrative health (IH) coaching as developed in three different interventions offered through a major medical center, as a step toward further defining the field of health coaching. An organizational case study was conducted with document analysis and interviews. Interviewees were the first six IH coaches at Duke Integrative Medicine who provided 360 clients with individual and/or group coaching (two to 28 sessions) in a randomized clinical study and two work-site wellness programs. Qualitative analysis using the constant comparative method was conducted. Integrative health coaching is characterized by a process of self-discovery that informs goal setting and builds internal motivation by linking clients' goals to their values and sense of purpose. Time, commitment, and motivation are necessary in the IH coaching process. The underpinnings of IH coaching are distinct from the medical model, and the process is distinct from health education, executive coaching, and psychotherapy. Integrative health coaching fits well with the assumptions of integrative medicine and has a role in supporting behavior change. Copyright © 2011. Published by Elsevier Inc.

  4. Roadmaster Roading Contractors Case Study

    Directory of Open Access Journals (Sweden)

    Hazel Taylor

    1999-01-01

    Full Text Available Systems analysis students seldom experience the practical difficulties of the initial investigation into a client’s requirements. They get little chance to practice the skills they need to investigate complex and confused problem situations, or to appreciate the wider organizational issues that can impact on a situation. This teaching case is designed to give students the opportunity to practice and apply investigation skills and to challenge them to consider the wider work environment when considering possible solutions to a problem situation. The case is conducted as a role-play, with students acting as systems analysts and teaching staff role-playing the clients. The students develop a report analyzing the client’s situation based on the issues that arise during the interviews. Feed-back sessions focus on discussing how well the students applied various interviewing strategies previously covered in lectures, and on the wider organizational problems that could impact proposed information system solutions.

  5. Bioremediation case studies: Abstracts. Final report

    International Nuclear Information System (INIS)

    Devine, K.

    1992-03-01

    The report contains abstracts of 132 case studies of bioremediation technology applied to hazardous waste clean-up. It was prepared to compile bioremediation studies in a variety of locations and treating diverse contaminants, most of which were previously undocumented. All data are based on vendor-supplied information and there was no opportunity to independently confirm its accuracy. These 132 case studies, from 10 different biotechnology companies, provide users with reference information about on-going and/or completed field applications and studies. About two-thirds of the cases were at full-scale clean-up level with the remainder at pilot or laboratory scale. In 74 percent of the cases, soil was at least one of the media treated. Soil alone accounts for 46 percent of the cases. Petroleum-related wastes account for the largest contaminant with 82 cases. Thirty-one states are represented in the case studies

  6. Characterization of Seasonal Influenza Virus Type and Subtypes Isolated from Influenza Like Illness Cases of 2012.

    Science.gov (United States)

    Upadhyay, B P; Ghimire, P; Tashiro, M; Banjara, M R

    Background Seasonal influenza is one of the increasing public health burdens in Nepal. Objective The objective of this study was to isolate and characterize the influenza virus type and subtypes of Nepal. Method A total of 1536 throat swab specimens were collected from January to December 2012. Total ribonucleic acid was extracted using Qiagen viral nucleic acid extraction kit and polymerase chain reaction assay was performed following the US; CDC Real-time PCR protocol. Ten percent of positive specimens were inoculated onto Madin-Darby Canine Kidney cells. Isolates were characterized by using reference ferret antisera. Result Of the total specimens (n=1536), influenza virus type A was detected in 196 (22%) cases; of which 194 (99%) were influenza A (H1N1) pdm09 and 2 (1 %) were influenza A/H3 subtype. Influenza B was detected in 684 (76.9%) cases. Influenza A (H1N1) pdm09, A/H3 and influenza B virus were antigenically similar to the recommended influenza virus vaccine candidate of the year 2012. Although sporadic cases of influenza were observed throughout the year, peak was observed during July to November. Conclusion Similar to other tropical countries, A (H1N1) pdm09, A/H3 and influenza B viruses were co-circulated in Nepal.

  7. Tank 4 Characterization, Settling, And Washing Studies

    International Nuclear Information System (INIS)

    Bannochie, C.; Pareizs, J.; Click, D.; Zamecnik, J.

    2009-01-01

    A sample of PUREX sludge from Tank 4 was characterized, and subsequently combined with a Tank 51 sample (Tank 51-E1) received following Al dissolution, but prior to a supernate decant by the Tank Farm, to perform a settling and washing study to support Sludge Batch 6 preparation. The sludge source for the majority of the Tank 51-E1 sample is Tank 12 HM sludge. The Tank 51-E1 sample was decanted by SRNL prior to use in the settling and washing study. The Tank 4 sample was analyzed for chemical composition including noble metals. The characterization of the Tank 51-E1 sample, used here in combination with the Tank 4 sample, was reported previously. SRNL analyses on Tank 4 were requested by Liquid Waste Engineering (LWE) via Technical Task Request (TTR) HLE-TTR-2009-103. The sample preparation work is governed by Task Technical and Quality Assurance Plan (TTQAP), and analyses were controlled by an Analytical Study Plan and modifications received via customer communications. Additional scope included a request for a settling study of decanted Tank 51-E1 and a blend of decanted Tank 51-E1 and Tank 4, as well as a washing study to look into the fate of undissolved sulfur observed during the Tank 4 characterization. The chemistry of the Tank 4 sample was modeled with OLI Systems, Inc. StreamAnalyzer to determine the likelihood that sulfate could exist in this sample as insoluble Burkeite (2Na 2 SO 4 · Na 2 CO 3 ). The OLI model was also used to predict the composition of the blended tank materials for the washing study. The following conclusions were drawn from the Tank 4 analytical results reported here: (1) Any projected blend of Tank 4 and the current Tank 51 contents will produce a SB6 composition that is lower in Ca and U than the current SB5 composition being processed by DWPF. (2) Unwashed Tank 4 has a relatively large initial S concentration of 3.68 wt% on a total solids basis, and approximately 10% of the total S is present as an insoluble or undissolved form

  8. Liverpool Telecare Pilot: case studies

    Directory of Open Access Journals (Sweden)

    Nigel Barnes

    2006-09-01

    Full Text Available Telecare services use information and communications technology (ICT to support the provision of care to people in their own homes. This paper describes a pilot telecare service employed by Liverpool (UK City Council to support a sample of their frail and elderly social services users. The pilot has been running for over two years and has been deployed for 21 individuals in Liverpool. In this paper we present the pilot system and provide real example cases which help to illustrate the benefits of such a system.

  9. Associative Visual Agnosia: A Case Study

    OpenAIRE

    Charnallet, A.; Carbonnel, S.; David, D.; Moreaud, O.

    2008-01-01

    We report a case of massive associative visual agnosia. In the light of current theories of identification and semantic knowledge organization, a deficit involving both levels of structural description system and visual semantics must be assumed to explain the case. We suggest, in line with a previous case study [1], an alternative account in the framework of (non abstractive) episodic models of memory [4].

  10. Associative visual agnosia: a case study.

    Science.gov (United States)

    Charnallet, A; Carbonnel, S; David, D; Moreaud, O

    2008-01-01

    We report a case of massive associative visual agnosia. In the light of current theories of identification and semantic knowledge organization, a deficit involving both levels of structural description system and visual semantics must be assumed to explain the case. We suggest, in line with a previous case study, an alternative account in the framework of (non abstractive) episodic models of memory.

  11. Study on Case Teaching of Financial Management

    Science.gov (United States)

    Che, Zhenghong; Che, Zhengmei

    2011-01-01

    Case teaching is an efficient teaching method of management. It plays an important role to enhance the students' ability to practice the theory. However, case teaching of financial management has not achieved the expected results. The paper aims to study the importance, characteristics and corresponding methods of case teaching method of financial…

  12. Case studies of selected Project "Flash" events

    Directory of Open Access Journals (Sweden)

    K. A. Nicolaides

    2009-03-01

    Full Text Available Flooding is a consequence of the prevailing meteorological situation, the intensity and duration of precipitation, geomorphology, human activities over a geographical region and other factors. Floods result in damage and destruction of infrastructure and private property and, in some cases, in fatalities. Flash floods are sudden and quite localized in extend, characterized by excessive amounts of rainfall within a short period of time and are distinguished from other floods by their degree of severity. The broader knowledge concerning flash floods is useful for the better understanding of the underlying thermodynamic and dynamic mechanisms, as well as the associated physical processes. The wider understanding of flashfloods can form part of an integrated system for short and very short forecasting of these events. In the present study, the synoptic, dynamic and thermodynamic conditions during the development of a baroclinic depression which affected the area of Cyprus on 6 November 2005 are studied. The depression was associated with extreme weather phenomena, such as thunderstorms, a water spout and high precipitation accumulations. The results indicate the importance of the dynamic parameters in the system's development and the thermodynamic analysis has shown the convective potential of the atmosphere.

  13. Identification and characterization of Department of Energy special-case radioactive waste

    International Nuclear Information System (INIS)

    Williams, R.E.; Kudera, D.E.

    1990-01-01

    This paper identifies and characterizes Department of Energy (DOE) special-case radioactive wastes. Included in this paper are descriptions of the special-case waste categories and their volumes and curie contents, as well as discussions of potential methods for management of these special-case wastes. Work on extensive inventories of DOE-titled special-case waste are still in progress. 1 tab

  14. Tribological characterization of the drill collars and casing friction couples

    Science.gov (United States)

    Ripeanu, R. G.; Badicioiu, M.; Caltaru, M.; Dinita, A.; Laudacescu, E.

    2018-01-01

    Drill collars are special pipes used in the drilling of wells for weighting the drill bit, enabling it to drill through the rock. In the drilling process, the drill collars are exposed to an intensive wear due to friction on inner surface of casing wall. In order to evaluate the tribological behaviour of this friction couple, paper presents the drill collars parent material, reconditioned and casing pipe chemical composition, microstructures, hardness and friction tests. For friction tests were prepared samples extracted from new and reconditioned drill collars and from casing pipes and tested on a universal tribometer. Were used plane-on-disk surface friction couples and tests were conducted at two sliding speeds and three normal loads for each materials couple. Plane static partner samples were extracted from casing pipes and disks samples were extracted from new and reconditioned drill collars. Were obtained friction coefficients values and also the temperatures increasing values due to friction working tests parameters. The temperature increasing values were obtained by measuring it with an infrared thermographic camera.

  15. Case Study of the NENE Code Project

    National Research Council Canada - National Science Library

    Kendall, Richard; Post, Douglass; Mark, Andrew

    2007-01-01

    ...) Program is sponsoring a series of case studies to identify the life cycles, workflows, and technical challenges of computational science and engineering code development that are representative...

  16. How To Set Up Your Own Small Business. Service Company Case Study. Manufacturing Firm Case Study. Retail Store Case Study.

    Science.gov (United States)

    Fallek, Max

    This collection of case studies is intended for use in a course in setting up a small business. The first, a case study of the process of setting up a service company, covers analyzing the pros and cons of starting one's own business, assessing the competition and local market, and selecting a site for and financing the business. The principal…

  17. A Toxicology and Characterization Study of Microplastics

    Science.gov (United States)

    Parker, Amy; Sullivan, Kelley; n/a Collaboration

    Plastic is everywhere. Microplastic particles are found in our toothpaste and soap, and are also created when larger plastics degrade under natural forces and sunlight. Studies have shown that filter feeders in aquatic systems eat microplastics, which transports plastic up the food chain. We used fluorescence microscopy to characterize the size, shape, and types of plastic found in several personal care products in order to create a clear picture of a significant source of microplastics found in our local Cayuga Lake ecosystem in Upstate New York. We also studied toxin absorption and emission of these plastics using environmentally relevant concentrations of BPA. For Neutrogena face scrub, the microplastics were polyethylene and roughly pill shaped. The majority of these microplastics are either smaller than 0.1 mm2, or were distributed in a bell-shaped curve about 0.5 mm2. The concentration of a solution of environmentally relevant BPA that microplastics were immersed in decreased by 13% over a 12-hour period. These results indicate that these microplastics pose a threat to organisms in the environment - they are small enough and shaped appropriately to be mistaken as prey, and they absorb toxins quickly. As the number of microplastics exponentially build up in the environment, the food chain will be negatively affected. Ithaca College DANA Student Internship program.

  18. [Turner syndrome: Study of 42 cases].

    Science.gov (United States)

    Bahíllo-Curieses, M Pilar; Prieto-Matos, Pablo; Quiroga González, Rocío; Regueras Santos, Laura; Blanco Barrio, Amaya; Rupérez Peña, Sara

    2016-10-21

    Turner syndrome (TS) is characterized by short stature, gonadal dysgenesis, and total or partial loss of X chromosome. A historical cohorts study of patients with TS≤18 years old followed up in public hospitals in Castilla y Leon was undertaken. Forty-two female patients were included (prenatal diagnosis 11.9%, neonatal diagnosis 14.3%) with current median age 11.9±4.2 years. Short stature was the reason for consultation in 87.1%. Total monosomy of X chromosome was present in 40.5%. The most frequently associated comorbidity was opthalmological (50%), with heart defects in 23.8%. Ninety-three percent were treated with growth hormone (GH), mean age at the beginning of treatment was 7.43±3.4 years and mean height standard deviation was -2.84±1.08. Final height was reached in 10 patients only (mean final height 151.47±6.09cm). Chronological age of puberty induction was 13.2±0.94 years (bone age 12.47±1.17 years). Short stature was an important clinical sign for the diagnosis of TS, accompanied in some cases by other findings, with good response to GH treatment. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

  19. Materials characterization techniques

    National Research Council Canada - National Science Library

    Zhang, Sam; Li, L; Kumar, Ashok

    2009-01-01

    "With an emphasis on practical applications and real-world case studies, Materials Characterization Techniques presents the principles of widely used advanced surface and structural characterization...

  20. Biosynthesis, characterization and antimicrobial study of silver ...

    African Journals Online (AJOL)

    Both the characterization and antimicrobial activity test were very successful and could lead to significant economic viability, as well as being environmentally friendly for treatment of some infectious diseases. Keywords: Syzygium guineenses, Green Chemistry, Spectroscopy, Optoelectronics, Biomedical Sensors ...

  1. Using Case Studies to Teach Courtesy Strategies.

    Science.gov (United States)

    Moore, Patrick

    1990-01-01

    Explains some courtesy techniques that technical professionals can use to deal with interpersonal problems that arise in writing situations. Presents three case studies with sample responses to show how case studies can teach these courtesy strategies to technical writing students. (MM)

  2. A Comparative Comment on the Case Studies

    DEFF Research Database (Denmark)

    Kjeldsen, Christian Christrup; Ley, Thomas; Jensen, Niels Rosendal

    2012-01-01

    Denne konklusion sammenfatter hovedtrækkene af de gennemførte case studies i WorkAble-projektet. Vigtige pointer er, at unge på tværs af de forskellige case studies har vanskeligt ved at blive hørt og taget alvorligt. I stedet spises de af med "realistisk vejledning" eller dårlige uddannelses- og...

  3. Reverse logistics: A review of case studies

    NARCIS (Netherlands)

    Brito, de M.P.; Dekker, Rommert; Flapper, S.D.P.; Fleischmann, B.; Klose, A.

    2004-01-01

    This paper gives an overview of scientific literature that describes and discusses cases of reverse logistics activities in practice. Over sixty case studies are considered. Based on these studies we are able to indicate critical factors for the practice of reverse logistics. In addition we compare

  4. A Case Study of "Empathetic Teaching Artistry"

    Science.gov (United States)

    Risner, Doug

    2014-01-01

    This case study is one of twenty cases derived from Anderson and Risner's international study of teaching artists in dance, and theatre, which investigated participants' (n=172) artistic and academic preparation in dance, and theatre, initial entry into the teaching artist field, rewards, challenges, and obstacles in participants' work, artists'…

  5. The Danish National Case Study Report

    DEFF Research Database (Denmark)

    Brodersen, Søsser; Jørgensen, Michael Søgaard

    Three case studies from Danish science shops within the environmental field are analysed with respect to societal background, interaction between the involved actors and the societal impact of the co-operation. The report is one of the seven national case study reports from the EU...

  6. Outage management: A case study

    International Nuclear Information System (INIS)

    Haber, S.B.; Barriere, M.T.; Roberts, K.H.

    1992-01-01

    Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission's (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study

  7. Five case studies of multifamily weatherization programs

    Energy Technology Data Exchange (ETDEWEB)

    Kinney, L; Wilson, T.; Lewis, G. [Synertech Systems Corp. (United States); MacDonald, M. [Oak Ridge National Lab., TN (United States)

    1997-12-31

    The multifamily case studies that are the subject of this report were conducted to provide a better understanding of the approach taken by program operators in weatherizing large buildings. Because of significant variations in building construction and energy systems across the country, five states were selected based on their high level of multifamily weatherization. This report summarizes findings from case studies conducted by multifamily weatherization operations in five cities. The case studies were conducted between January and November 1994. Each of the case studies involved extensive interviews with the staff of weatherization subgrantees conducting multifamily weatherization, the inspection of 4 to 12 buildings weatherized between 1991 and 1993, and the analysis of savings and costs. The case studies focused on innovative techniques which appear to work well.

  8. A case study of Douala

    Indian Academy of Sciences (India)

    In this paper, demand of energy (heating/cooling) in the buildings is discussed in Douala, Cameroon. Daily data of the last 40 years coming from five weather stations of Cameroon have been studied. Some forecasts have been carried out with 14 GCM models, associated to three future climate scenarios B1, A2, and A1B.

  9. A chromite ore case study

    African Journals Online (AJOL)

    2009-05-15

    May 15, 2009 ... of Cr(VI). If this is true, it could have serious consequences for South African chromite mines and the local environment. ... study proved that the Cr(VI) content of chromite samples is .... used during pulvizising experiments was dried at 40ºC for 1 d ... This is the simplest Cr(VI) extraction method and is similar.

  10. Case Study on Quality Education

    Science.gov (United States)

    Habib, Zahida

    2011-01-01

    Quality of Education, especially at Primary level, is an important issue to be discussed at the International Forum. This study highlights the quality of primary education through a comparison of the quality of Community Model Schools and Govt. Girls Primary Schools in Pakistan. Community Model Schools were established under Girls Primary…

  11. Reservoir characterization by multiattribute analysis: The Orito field case

    Directory of Open Access Journals (Sweden)

    Montes Luis

    2010-12-01

    Full Text Available

    In order to characterize the Caballos formation reservoir in the Orito field in the Putumayo basin - Colombia, a multiattribute analysis was applied to a 50 km2 seismic volume along with 16 boreholes. Some properties of the reservoir were reliably estimated and very accurate when compared with well data. The porosity, permeability and volume of shale were calculated in the seismic volume by at least second order multivariate polynomial. A good correlation between porosity and acoustic impedance was observed by means of crossplot analysis performed on properties measured and estimated in cores or borehole logs as well as on properties calculated in the seismic volume. The estimated property values were well behaved according to the rocks physics analysis. With the property maps generated and the geological environments of the reservoir a new interpretation of the Caballos formation was established. High correlation coefficients and low estimated errors point out competence to calculate these three reservoir properties in places far from the influence of the wells. The multiple equation system was established through weighted hierarchical grouping of attributes and their coefficients calculated applying the inverse generalized matrix method.

  12. Theoretical pluralism in psychoanalytic case studies.

    Science.gov (United States)

    Willemsen, Jochem; Cornelis, Shana; Geerardyn, Filip M; Desmet, Mattias; Meganck, Reitske; Inslegers, Ruth; Cauwe, Joachim M B D

    2015-01-01

    The aim of this study is to provide an overview of the scientific activity of different psychoanalytic schools of thought in terms of the content and production of case studies published on ISI Web of Knowledge. Between March 2013 and November 2013, we contacted all case study authors included in the online archive of psychoanalytic and psychodynamic case studies (www.singlecasearchive.com) to inquire about their psychoanalytic orientation during their work with the patient. The response rate for this study was 45%. It appears that the two oldest psychoanalytic schools, Object-relations psychoanalysis and Ego psychology or "Classical psychoanalysis" dominate the literature of published case studies. However, most authors stated that they feel attached to two or more psychoanalytic schools of thought. This confirms that the theoretical pluralism in psychoanalysis stretches to the field of single case studies. The single case studies of each psychoanalytic school are described separately in terms of methodology, patient, therapist, or treatment features. We conclude that published case studies features are fairly similar across different psychoanalytic schools. The results of this study are not representative of all psychoanalytic schools, as some do not publish their work in ISI ranked journals.

  13. Theoretical pluralism in psychoanalytic case studies

    Science.gov (United States)

    Willemsen, Jochem; Cornelis, Shana; Geerardyn, Filip M.; Desmet, Mattias; Meganck, Reitske; Inslegers, Ruth; Cauwe, Joachim M. B. D.

    2015-01-01

    The aim of this study is to provide an overview of the scientific activity of different psychoanalytic schools of thought in terms of the content and production of case studies published on ISI Web of Knowledge. Between March 2013 and November 2013, we contacted all case study authors included in the online archive of psychoanalytic and psychodynamic case studies (www.singlecasearchive.com) to inquire about their psychoanalytic orientation during their work with the patient. The response rate for this study was 45%. It appears that the two oldest psychoanalytic schools, Object-relations psychoanalysis and Ego psychology or “Classical psychoanalysis” dominate the literature of published case studies. However, most authors stated that they feel attached to two or more psychoanalytic schools of thought. This confirms that the theoretical pluralism in psychoanalysis stretches to the field of single case studies. The single case studies of each psychoanalytic school are described separately in terms of methodology, patient, therapist, or treatment features. We conclude that published case studies features are fairly similar across different psychoanalytic schools. The results of this study are not representative of all psychoanalytic schools, as some do not publish their work in ISI ranked journals. PMID:26483725

  14. Making a case for case studies in psychotherapy training

    DEFF Research Database (Denmark)

    Mackrill, Thomas Edward; Iwakabe, Shigeru

    2013-01-01

    articulated explicitly or researched systematically in spite of its cardinal importance. An analysis of the role of case studies in psychotherapy training is presented. Reading, watching, or hearing about cases can offer novice psychotherapists access to a closed world; access to psychological theory...... in action; access to whole courses of therapy; access to different approaches; access to significant moments; access to the therapeutic relationship; access to a wide range of client types; access to working in different contexts; and the opportunity of identifying with therapists and clients. Writing...

  15. Arctic bioremediation -- A case study

    International Nuclear Information System (INIS)

    Smallbeck, D.R.; Ramert, P.C.; Liddell, B.V.

    1994-01-01

    This paper discusses the use of bioremediation as an effective method to clean up diesel-range hydrocarbon spills in northern latitudes. The results of a laboratory study of microbial degradation of hydrocarbons under simulated arctic conditions showed that bioremediation can be effective in cold climates and led to the implementation of a large-scale field program. The results of 3 years of field testing have led to a significant reduction in diesel-range hydrocarbon concentrations in the contaminated area

  16. Schematic representation of case study research designs.

    Science.gov (United States)

    Rosenberg, John P; Yates, Patsy M

    2007-11-01

    The paper is a report of a study to demonstrate how the use of schematics can provide procedural clarity and promote rigour in the conduct of case study research. Case study research is a methodologically flexible approach to research design that focuses on a particular case - whether an individual, a collective or a phenomenon of interest. It is known as the 'study of the particular' for its thorough investigation of particular, real-life situations and is gaining increased attention in nursing and social research. However, the methodological flexibility it offers can leave the novice researcher uncertain of suitable procedural steps required to ensure methodological rigour. This article provides a real example of a case study research design that utilizes schematic representation drawn from a doctoral study of the integration of health promotion principles and practices into a palliative care organization. The issues discussed are: (1) the definition and application of case study research design; (2) the application of schematics in research; (3) the procedural steps and their contribution to the maintenance of rigour; and (4) the benefits and risks of schematics in case study research. The inclusion of visual representations of design with accompanying explanatory text is recommended in reporting case study research methods.

  17. Hybrid Enrichment Verification Array: Module Characterization Studies

    Energy Technology Data Exchange (ETDEWEB)

    Zalavadia, Mital A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Smith, Leon E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); McDonald, Benjamin S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kulisek, Jonathan A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mace, Emily K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Deshmukh, Nikhil S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-03-01

    The work presented in this report is focused on the characterization and refinement of the Hybrid Enrichment Verification Array (HEVA) approach, which combines the traditional 186-keV 235U signature with high-energy prompt gamma rays from neutron capture in the detector and surrounding collimator material, to determine the relative enrichment and 235U mass of the cylinder. The design of the HEVA modules (hardware and software) deployed in the current field trial builds on over seven years of study and evolution by PNNL, and consists of a ø3''×3'' NaI(Tl) scintillator coupled to an Osprey digital multi-channel analyzer tube base from Canberra. The core of the HEVA methodology, the high-energy prompt gamma-ray signature, serves as an indirect method for the measurement of total neutron emission from the cylinder. A method for measuring the intrinsic efficiency of this “non-traditional” neutron signature and the results from a benchmark experiment are presented. Also discussed are potential perturbing effects on the non-traditional signature, including short-lived activation of materials in the HEVA module. Modeling and empirical results are presented to demonstrate that such effects are expected to be negligible for the envisioned implementation scenario. In comparison to previous versions, the new design boosts the high-energy prompt gamma-ray signature, provides more flexible and effective collimation, and improves count-rate management via commercially available pulse-processing electronics with a special modification prompted by PNNL.

  18. Associative Visual Agnosia: A Case Study

    Directory of Open Access Journals (Sweden)

    A. Charnallet

    2008-01-01

    Full Text Available We report a case of massive associative visual agnosia. In the light of current theories of identification and semantic knowledge organization, a deficit involving both levels of structural description system and visual semantics must be assumed to explain the case. We suggest, in line with a previous case study [1], an alternative account in the framework of (non abstractive episodic models of memory [4].

  19. INTERIORITY - a prefab case study

    DEFF Research Database (Denmark)

    Hvejsel, Marie Frier

    Dealing with the general theme of domestic architectural quality, the PhD thesis ‘INTERIORITY’ takes its point of departure in the continuous and increasing need to improve our capability as architects to theoretically articulate the intangible concept of quality, and to reveal it through an active...... been motivated by the particular hypothesis that an introduction of the notion of interiority, as an ability of the spatial envelope itself to address the sensuous scale of furniture, unfolds a particular dual critical potential signifying our experience of domestic architectural quality: On the one......, tectonically. Hence, it has been a particular idea of the study to explore the relation between furniture, the spatial envelope itself, and its construct by using furniture as an architectural concept. Consequently, the thesis has specifically investigated whether this notion of interiority, describing...

  20. Case study on printed matter

    DEFF Research Database (Denmark)

    – how important are emissions of chemicals? J Clean Prod 17, 115 – 128. Larsen HF (2004). Assessment of chemical emissions in life cycle impact assessment - focus on low substance data availability and ecotoxicity effect indicators. Ph.D. Thesis, October 2004. Department of Manufacturing, Engineering...... and Management. Technical University of Denmark. http://www.tempo.ipl.dtu.dk/ipl/upload/publ/PhD-thesis-rev.pdf Figure 1 Comparison of weighted LCA profiles with or without chemical related impact categories included (percentage of total, milli-person-equivalents-targeted, mPET). The avoided energy consumptions...... global warming, acidification and nutrification. The studies focus on energy consumption including the emissions and impact categories related to energy. The chemical-related impact categories comprising ecotoxicity and human toxicity are not included at all or only to a limited degree. In this paper we...

  1. Characterization of drug susceptibility of Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection

    Directory of Open Access Journals (Sweden)

    G. V. Panov

    2015-01-01

    Full Text Available The paper characterizes drug susceptibility in Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection. The investigators have studied the spectrum of drug resistance in Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with and without HIV infection (172 and 309 clinical isolates, respectively. There are differences in the rate of primary drug resistance to antituberculosis drugs in patients with and without HIV infection (59 and 43.5% of the cases, respectively. The HIV-infected have also shown high rifampicin resistance rates in Mycobacterium tuberculosis (41.7%. The reasons for these differences are as yet unknown and call for further investigation.

  2. Antiphospholipid syndrome: A case study

    International Nuclear Information System (INIS)

    Davies, T.

    1998-01-01

    Full text: A forty-two-year-old male presented to the Royal Adelaide Hospital with symptoms of increasing shortness of breath, swelling in both ankles, petechial rash and blood in his sputum. Initial investigations showed cardiomegaly, right ventricular hypertrophy, patchy lung infiltrates, a platelet count of 1500 and a clotting time of 60 seconds. A V/Q scan indicated a high probability of pulmonary embolism. Further investigations showed that the patient was positive for lupus anticoagulant and cardiolipin antibodies. A diagnosis of primary antiphospholipid syndrome was made. The patient''s high risk of strokes and hemorrhaging prompted investigation by a 99 mTc-HMPAO brain scan. Further V/Q scans were performed to follow up the initial finding of multiple pulmonary embolism and a R-L shunt study was performed to investigate a left subclavian murmur. The patient was admitted for four weeks and began treatment which included cyclaphosphamide, corticosteroids and plasmaphoresis and was discharged when stable. Over the next six months he was re admitted three times for relapse of antiphospholipid syndrome. On his fourth admission he collapsed and died five hours after admission. Cause of death was due to cardiac arrhythmia secondary to severe right ventricular hypertrophy and dilation. The effects of antiphospholipid syndrome was believed to be responsible for this outcome

  3. Antiphospholipid syndrome: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Davies, T. [Royal Adelaide Hospital, Adelaide, SA (Australia). Department of Nuclear Medicine

    1998-03-01

    Full text: A forty-two-year-old male presented to the Royal Adelaide Hospital with symptoms of increasing shortness of breath, swelling in both ankles, petechial rash and blood in his sputum. Initial investigations showed cardiomegaly, right ventricular hypertrophy, patchy lung infiltrates, a platelet count of 1500 and a clotting time of 60 seconds. A V/Q scan indicated a high probability of pulmonary embolism. Further investigations showed that the patient was positive for lupus anticoagulant and cardiolipin antibodies. A diagnosis of primary antiphospholipid syndrome was made. The patient``s high risk of strokes and hemorrhaging prompted investigation by a {sup 99}mTc-HMPAO brain scan. Further V/Q scans were performed to follow up the initial finding of multiple pulmonary embolism and a R-L shunt study was performed to investigate a left subclavian murmur. The patient was admitted for four weeks and began treatment which included cyclaphosphamide, corticosteroids and plasmaphoresis and was discharged when stable. Over the next six months he was re admitted three times for relapse of antiphospholipid syndrome. On his fourth admission he collapsed and died five hours after admission. Cause of death was due to cardiac arrhythmia secondary to severe right ventricular hypertrophy and dilation. The effects of antiphospholipid syndrome was believed to be responsible for this outcome.

  4. Music in context : Four case studies

    NARCIS (Netherlands)

    Randwijck, R.J.C. van

    2008-01-01

    In his thesis entitled “Music in Context. Four Case Studies”, R.J.C. van Randwijck investigates the context in which music has been created. It is a search in Four Case Studies, approaching four pieces of music from the context in which they were written in order to understand their meaning. The

  5. Case Study: A Separation of Powers Lesson.

    Science.gov (United States)

    Jenkins, Steve

    1986-01-01

    Presents a case study involving students in the issue of separation of powers as applied to the 1952 Immigration and Nationality Act. Students examine the case of Jagdish Rai Chadha, an immigrant threatened with deportation whose problems resulted in 1983 U.S. Supreme Court decision declaring legislative veto provision of Immigration and…

  6. Implementing Product Platforms: A Case Study

    DEFF Research Database (Denmark)

    Nielsen, Ole Fiil; Mortensen, Niels Henrik

    2006-01-01

    The paper describes a case study dealing with the process of creating and implementing a product platform. The paper espessially deals with the fact that to obtain the benefits of platforms a permanent change in behaviour in product development must be ensured. This change in behaviour requires...... acceptance and approval from the organisation in general and the commitment from management to enforce agreed-upon decisions. The case study itself was performed in the Danish company LEGO Group. The case study had two objectives: To create a technical architecture and align this architecture...

  7. Case Study: Mini-Case Studies: Small Infusions of Active Learning for Large-Lecture Courses

    Science.gov (United States)

    Carloye, Lisa

    2017-01-01

    In this article, the author introduces the usage of case studies to be an excellent method for engaging students through stories. The author notes she developed a series of mini-case studies that can be implemented, with a little advance preparation, within a 10- to 15-minute window during lecture. What makes them "mini" case studies?…

  8. Case-control studies in neurosurgery.

    Science.gov (United States)

    Nesvick, Cody L; Thompson, Clinton J; Boop, Frederick A; Klimo, Paul

    2014-08-01

    Observational studies, such as cohort and case-control studies, are valuable instruments in evidence-based medicine. Case-control studies, in particular, are becoming increasingly popular in the neurosurgical literature due to their low cost and relative ease of execution; however, no one has yet systematically assessed these types of studies for quality in methodology and reporting. The authors performed a literature search using PubMed/MEDLINE to identify all studies that explicitly identified themselves as "case-control" and were published in the JNS Publishing Group journals (Journal of Neurosurgery, Journal of Neurosurgery: Pediatrics, Journal of Neurosurgery: Spine, and Neurosurgical Focus) or Neurosurgery. Each paper was evaluated for 22 descriptive variables and then categorized as having either met or missed the basic definition of a case-control study. All studies that evaluated risk factors for a well-defined outcome were considered true case-control studies. The authors sought to identify key features or phrases that were or were not predictive of a true case-control study. Those papers that satisfied the definition were further evaluated using the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist. The search detected 67 papers that met the inclusion criteria, of which 32 (48%) represented true case-control studies. The frequency of true case-control studies has not changed with time. Use of odds ratios (ORs) and logistic regression (LR) analysis were strong positive predictors of true case-control studies (for odds ratios, OR 15.33 and 95% CI 4.52-51.97; for logistic regression analysis, OR 8.77 and 95% CI 2.69-28.56). Conversely, negative predictors included focus on a procedure/intervention (OR 0.35, 95% CI 0.13-0.998) and use of the word "outcome" in the Results section (OR 0.23, 95% CI 0.082-0.65). After exclusion of nested case-control studies, the negative correlation between focus on a procedure

  9. Development of taxon-specific sequence characterized amplified region (SCAR) markers based on actin sequences and DNA amplification fingerprinting (DAF): a case study in the Phoma exigua species complex.

    Science.gov (United States)

    Aveskamp, Maikel M; Woudenberg, Joyce H C; de Gruyter, Johannes; Turco, Elena; Groenewald, Johannes Z; Crous, Pedro W

    2009-05-01

    Phoma exigua is considered to be an assemblage of at least nine varieties that are mainly distinguished on the basis of host specificity and pathogenicity. However, these varieties are also reported to be weak pathogens and secondary invaders on non-host tissue. In practice, it is difficult to distinguish P. exigua from its close relatives and to correctly identify isolates up to the variety level, because of their low genetic variation and high morphological similarity. Because of quarantine issues and phytosanitary measures, a robust DNA-based tool is required for accurate and rapid identification of the separate taxa in this species complex. The present study therefore aims to develop such a tool based on unique nucleotide sequence identifiers. More than 60 strains of P. exigua and related species were compared in terms of partial actin gene sequences, or analysed using DNA amplification fingerprinting (DAF) with short, arbitrary, mini-hairpin primers. Fragments in the fingerprint unique to a single taxon were identified, purified and sequenced. Alignment of the sequence data and subsequent primer trials led to the identification of taxon-specific sequence characterized amplified regions (SCARs), and to a set of specific oligonucleotide combinations that can be used to identify these organisms in plant quarantine inspections.

  10. Drugs of abuse, cytostatic drugs and iodinated contrast media in tap water from the Madrid region (central Spain):A case study to analyse their occurrence and human health risk characterization.

    Science.gov (United States)

    Mendoza, A; Zonja, B; Mastroianni, N; Negreira, N; López de Alda, M; Pérez, S; Barceló, D; Gil, A; Valcárcel, Y

    2016-01-01

    This work analyses the presence of forty-eight emerging pollutants, including twenty-five drugs of abuse and metabolites, seventeen cytostatic drugs and six iodinated contrast media, in tap water from the Madrid Region. Analysis of the target compounds in the tap water was performed by means of (on-line or off-line) solid-phase extraction followed by analysis by liquid chromatography-tandem mass spectrometry. A preliminary human health risk characterization was undertaken for each individual compound and for different groups of compounds with a common mechanism of action found in tap water. The results of the study showed the presence of eight out of the twenty-five drugs of abuse and metabolites analysed, namely, the cocainics cocaine and benzoylecgonine, the amphetamine-type stimulants ephedrine, 3,4-methylenedioxymethamphetamine and methamphetamine, the opioid methadone and its metabolite 2-ethylene-1,5-dimethyl-3,3-diphenylpyrrolidine and, finally caffeine at concentrations ranging from 0.11 to 502 ng L(-1). Four out of the six analysed iodinated contrast media, namely, diatrizoate, iohexol, iomeprol and iopromide, were detected in at least one sample, with concentration values varying between 0.4 and 5 ng L(-1). Cytostatic compounds were not detected in any sample. Caffeine was the substance showing the highest concentrations, up to 502 ng L(-1), mainly in the drinking water sampling point located in Madrid city. Among the other drugs of abuse, the most abundant compounds were cocaine and benzoylecgonine, detected at concentrations ranging from 0.11 to 86 ng L(-1) and from 0.11 to 53 ng L(-1), respectively. Regarding iodinated contrast media, iohexol was the most ubiquitous and abundant compound, with a frequency of detection of 100% and concentrations from 0.5 to 5.0 ng L(-1) in basically the same range in all sampling points. Taking into account the results and types of treatment applied, ozonisation plus granular activated carbon filtration appears to be

  11. War And Reconstruction: Four Comparative Case Studies

    African Journals Online (AJOL)

    The four case studies are taken from four different continents, four different wars under .... and revolutionary changes in the structures and power relations in society and ..... general public accept nowadays that although states' rights were the ...

  12. BTS Case Study: The Galloway Family Home

    International Nuclear Information System (INIS)

    Brandegee Group

    1999-01-01

    Case study of an energy-efficient Habitat for Humanity house that uses 30% less energy than conventional residential construction. The project was part of the Jimmy Carter Work Project in rural Appalachia in 1997

  13. Abstracts of Remediation Case Studies, Volume 9

    Science.gov (United States)

    This report, published by the Federal Remediation Technologies Roundtable (FRTR), is a collection of recently published abstracts summarizing 13 cost and performance case studies on the use of remediation technologies at contaminated sites.

  14. Review of ORD Nanomaterial Case Studies Workshop

    Science.gov (United States)

    The following is a letter report from the Executive Committee of the BOSC concerning the review of the ORD Nanomaterial Case Studies Workshop: Developing a Comprehensive Environmental Assessment Research Strategy for Nanoscale Titanium Dioxide.

  15. Case Study: Pancreas cancer with Whipple's operation

    African Journals Online (AJOL)

    Keywords: pancreas cancer, Whipple procedure, SASPEN case study ..... Grade A. Grade B. Grade C. Nasogastric tube required. 4-7 days or reinserted > postoperative day 3 .... malabsorption and vitamin and mineral deficiencies are the most.

  16. Innovative Interpretive Qualitative Case Study Research Method ...

    African Journals Online (AJOL)

    lc2o

    The combined use of case study and systems theory is rarely discussed in the ... Scott, 2002), the main benefit of doing qualitative research is the patience ..... Teaching ICT to teacher candidates ... English Language Teachers. London: Arnold.

  17. Memory and Learning: A Case Study.

    Science.gov (United States)

    Webster, Raymond E.

    1986-01-01

    The usefulness of the Learning Efficency Test (LET), an approach to assessing the learning efficiency and short-term memory recall capacity in children, is described via a case study demonstrating the test's use to develop instructional strategies. (CL)

  18. Towards More Case Study Research in Entrepreneurship

    Directory of Open Access Journals (Sweden)

    Tom Duxbury

    2012-03-01

    Full Text Available Entrepreneurship as an emerging discipline has made good strides, but according to some, has fallen short of bringing its theory and literature up to the standards of others in the management sciences. Rich with the descriptive detail needed for insightful theory building in entrepreneurship, scholars have called for more case study research, particularly those incorporating non-retrospective and longitudinal observations. At the same time however, it has become rare to find such research published in A-level journals dedicated to entrepreneurship. A survey presented here of major entrepreneurship journals over the past six years revealed a publication rate of only 3% using the case study method. This presents a major impediment for developing fresh research in this field based upon the study of real cases. The author explores how the case study method has been applied to entrepreneurship research and provides recommendations for improved publication rates.

  19. Travel Efficiency Assessment Method: Three Case Studies

    Science.gov (United States)

    This slide presentation summarizes three case studies EPA conducted in partnership with Boston, Kansas City, and Tucson, to assess the potential benefits of employing travel efficiency strategies in these areas.

  20. Modalities of Generalization Through Single Case Studies.

    Science.gov (United States)

    Zittoun, Tania

    2017-06-01

    The value of case studies for theory building is still doubted in psychology. The paper argues for the importance of case studies and the possibility of generalizing from these for a specific sociocultural understanding of human development. The paper first clarifies the notion of abduction within case studies, drawing on pragmatists James and Peirce and expanding it with the work of Lewin, and argues that it is the core mechanism that allows generalization from case studies. The second section presents the possibility of generalizing from individual single case studies, for which not only the subjective perspective, but also the dynamics by which the social and cultural environment guide and enable the person's development, have to be accounted for. The third section elaborates the question of institutional case studies, where the challenge is to account both for institutional dynamics, and for persons' trajectories within; this is exemplified with an ongoing study on the process of obtaining citizenship in Switzerland. The paper briefly concludes by highlighting two possible implications of the paper, one concerning the process of theoretical reasoning, the other, the fact that sociocultural psychology could itself be seen as an institution in-the-making.

  1. Educational Potential of Case-Study Technology

    OpenAIRE

    Fedorinova, Zoya; Vorobeva, Victoria; Malyanova, Marina

    2015-01-01

    This article presents the results of phenomenological and typological analysis of case-study technology educational potential. The definition “educational potential of case-study technology” is given, the main characteristics of which are changed in communication and collaborative activity quality, appearance of educational initiatives, change of participants’ position in learning process, formation of “collective subject” in collaborative activity, increase of learning (subject) results. Dep...

  2. Performable Case Studies in Ethics Education.

    Science.gov (United States)

    Robeson, Richard; King, Nancy M P

    2017-09-12

    Bioethics education often includes the study of short stories, novels, plays, and films, because such materials present case examples that can highlight relevant issues and questions especially vividly for a wide range of students. In addition, creative writing is widely used in the education of health professional students and in continuing education settings for health professionals. There are very few academic or professional disciplines that do not use case studies, but the case study in dialogic form has not been standard practice for thousands of years. Dramatic arts casuistry-the creation and performance of short case studies designed specifically to raise bioethics issues for discussion-represents an application of literature and the medical humanities that is both unique and uniquely valuable. This essay describes the development and history of a course that has been successfully taught to medical students and graduate bioethics students, in which the class researches, writes, and performs a case study designed to elicit reflection and discussion about a topic and set of bioethics issues of current interest to both academic and general audiences. The model is also suited to the presentation and discussion of existing case studies, both live and via on-demand audio.

  3. Stochastic fuzzy environmental risk characterization of uncertainty and variability in risk assessments: A case study of polycyclic aromatic hydrocarbons in soil at a petroleum-contaminated site in China

    International Nuclear Information System (INIS)

    Hu, Yan; Wang, Zesen; Wen, Jingya; Li, Yu

    2016-01-01

    Highlights: • Deal with environmental quality guidelines absence in risk characterization. • Quantitative represention of uncertainty from environmental quality guidelines. • Quantitative represention of variability from contaminant exposure concentrations. • Establishment of stochastic-fuzzy environmental risk characterization approach framework. - Abstract: Better decisions are made using risk assessment models when uncertainty and variability are explicitly acknowledged. Uncertainty caused by a lack of uniform and scientifically supported environmental quality guidelines and variability in the degree of exposure of environmental systems to contaminants are here incorporated in a stochastic fuzzy environmental risk characterization (SFERC) approach. The approach is based on quotient probability distribution and environmental risk level fuzzy membership function methods. The SFERC framework was used to characterize the environmental risks posed by 16 priority polycyclic aromatic hydrocarbons (PAHs) in soil at a typical petroleum-contaminated site in China. This relied on integrating data from the literature and field and laboratory experiments. The environmental risk levels posed by the PAHs under four risk scenarios were determined using the SFERC approach, using “residential land” and “industrial land” environmental quality guidelines under “loose” and “strict” strictness parameters. The results showed that environmental risks posed by PAHs in soil are primarily caused by oil exploitation, traffic emissions, and coal combustion. The SFERC approach is an effective tool for characterizing uncertainty and variability in environmental risk assessments and for managing contaminated sites.

  4. Stochastic fuzzy environmental risk characterization of uncertainty and variability in risk assessments: A case study of polycyclic aromatic hydrocarbons in soil at a petroleum-contaminated site in China

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Yan [MOE Key Laboratory of Regional Energy Systems Optimization, Resources and Environmental Research Academy, North China Electric Power University, Beijing 102206 (China); State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environment Sciences, Beijing 100012 (China); Wang, Zesen [MOE Key Laboratory of Regional Energy Systems Optimization, Resources and Environmental Research Academy, North China Electric Power University, Beijing 102206 (China); Wen, Jingya [MOE Key Laboratory of Regional Energy Systems Optimization, Resources and Environmental Research Academy, North China Electric Power University, Beijing 102206 (China); Institute of Hydropower and Environment Research, Beijing 100012 (China); Li, Yu, E-mail: liyuxx8@hotmail.com [MOE Key Laboratory of Regional Energy Systems Optimization, Resources and Environmental Research Academy, North China Electric Power University, Beijing 102206 (China)

    2016-10-05

    Highlights: • Deal with environmental quality guidelines absence in risk characterization. • Quantitative represention of uncertainty from environmental quality guidelines. • Quantitative represention of variability from contaminant exposure concentrations. • Establishment of stochastic-fuzzy environmental risk characterization approach framework. - Abstract: Better decisions are made using risk assessment models when uncertainty and variability are explicitly acknowledged. Uncertainty caused by a lack of uniform and scientifically supported environmental quality guidelines and variability in the degree of exposure of environmental systems to contaminants are here incorporated in a stochastic fuzzy environmental risk characterization (SFERC) approach. The approach is based on quotient probability distribution and environmental risk level fuzzy membership function methods. The SFERC framework was used to characterize the environmental risks posed by 16 priority polycyclic aromatic hydrocarbons (PAHs) in soil at a typical petroleum-contaminated site in China. This relied on integrating data from the literature and field and laboratory experiments. The environmental risk levels posed by the PAHs under four risk scenarios were determined using the SFERC approach, using “residential land” and “industrial land” environmental quality guidelines under “loose” and “strict” strictness parameters. The results showed that environmental risks posed by PAHs in soil are primarily caused by oil exploitation, traffic emissions, and coal combustion. The SFERC approach is an effective tool for characterizing uncertainty and variability in environmental risk assessments and for managing contaminated sites.

  5. Epithelioid fibrous histiocytoma: molecular characterization of ALK fusion partners in 23 cases.

    Science.gov (United States)

    Dickson, Brendan C; Swanson, David; Charames, George S; Fletcher, Christopher Dm; Hornick, Jason L

    2018-05-01

    Epithelioid fibrous histiocytoma is a rare and distinctive cutaneous neoplasm. Most cases harbor ALK rearrangement and show ALK overexpression, which distinguish this neoplasm from conventional cutaneous fibrous histiocytoma and variants. SQSTM1 and VCL have previously been shown to partner with ALK in one case each of epithelioid fibrous histiocytoma. The purpose of this study was to examine a large cohort of epithelioid fibrous histiocytomas by next-generation sequencing to characterize the nature and prevalence of ALK fusion partners. A retrospective archival review was performed to identify cases of epithelioid fibrous histiocytoma (2012-2016). Immunohistochemistry was performed to confirm ALK expression. Targeted next-generation sequencing was applied on RNA extracted from formalin-fixed paraffin-embedded tissue to identify the fusion partners. Twenty-three cases fulfilled inclusion criteria. The mean patient age was 39 years (range, 8-74), there was no sex predilection, and >75% of cases involved the lower extremities. The most common gene fusions were SQSTM1-ALK (N=12; 52%) and VCL-ALK (N=7; 30%); the other four cases harbored novel fusion partners (DCTN1, ETV6, PPFIBP1, and SPECC1L). The pattern of ALK immunoreactivity was usually granular cytoplasmic (N=12; 52%) or granular cytoplasmic and nuclear (N=10; 43%); the case containing an ETV6 fusion partner showed nuclear staining alone. There was no apparent relationship between tumor morphology and the ALK fusion partner. In summary, SQSTM1 and VCL are the most common ALK fusion partners in epithelioid fibrous histiocytoma; DCTN1, ETV6, PPFIBP1, and SPECC1L represent rare fusion partners. The proteins encoded by these genes play diverse roles in scaffolding, cell adhesion, signaling, and transcription (among others) without clear commonalities. These findings expand the oncogenic promiscuity of many of these ALK fusion genes, which drive neoplasia in tumors of diverse lineages with widely varied clinical

  6. A Case Study about Communication Strategies

    Science.gov (United States)

    Lin, Grace Hui Chin

    2011-01-01

    The primary purpose of this case study was to identify what were Taiwanese University English as a Foreign Language (EFL) learners' perceptions about learning communication strategies. This study collected qualitative data about students' beliefs and attitudes as they learned communication strategies. The research question guiding the study was:…

  7. Predicting Students Drop Out: A Case Study

    Science.gov (United States)

    Dekker, Gerben W.; Pechenizkiy, Mykola; Vleeshouwers, Jan M.

    2009-01-01

    The monitoring and support of university freshmen is considered very important at many educational institutions. In this paper we describe the results of the educational data mining case study aimed at predicting the Electrical Engineering (EE) students drop out after the first semester of their studies or even before they enter the study program…

  8. Case Characterization, Clinical Features and Risk Factors in Drug-Induced Liver Injury

    Directory of Open Access Journals (Sweden)

    Aida Ortega-Alonso

    2016-05-01

    Full Text Available Idiosyncratic drug-induced liver injury (DILI caused by xenobiotics (drugs, herbals and dietary supplements presents with a range of both phenotypes and severity, from acute hepatitis indistinguishable of viral hepatitis to autoimmune syndromes, steatosis or rare chronic vascular syndromes, and from asymptomatic liver test abnormalities to acute liver failure. DILI pathogenesis is complex, depending on the interaction of drug physicochemical properties and host factors. The awareness of risk factors for DILI is arising from the analysis of large databases of DILI cases included in Registries and Consortia networks around the world. These networks are also enabling in-depth phenotyping with the identification of predictors for severe outcome, including acute liver failure and mortality/liver transplantation. Genome wide association studies taking advantage of these large cohorts have identified several alleles from the major histocompatibility complex system indicating a fundamental role of the adaptive immune system in DILI pathogenesis. Correct case definition and characterization is crucial for appropriate phenotyping, which in turn will strengthen sample collection for genotypic and future biomarkers studies.

  9. Case Study Research Methodology in Nursing Research.

    Science.gov (United States)

    Cope, Diane G

    2015-11-01

    Through data collection methods using a holistic approach that focuses on variables in a natural setting, qualitative research methods seek to understand participants' perceptions and interpretations. Common qualitative research methods include ethnography, phenomenology, grounded theory, and historic research. Another type of methodology that has a similar qualitative approach is case study research, which seeks to understand a phenomenon or case from multiple perspectives within a given real-world context.

  10. Case Study Report about Gender Impact Assessment

    DEFF Research Database (Denmark)

    Faber, Stine Thidemann; Agustin, Lise Rolandsen

    2013-01-01

    The aim of this national case study report is to take a closer look at the use of Gender Impact Assessments in Denmark in order to describe the Danish implementation of this specific Gender Mainstreaming method. By way of analyzing two selected cases (two law proposals put forward by The Danish...... Ministry of Employment and the Danish Ministry of Transport, respectively) the aim is to assess the transformative potential of GIA as it is performed in Denmark....

  11. Gigantic Suprapubic Lymphedema: A Case Study

    Directory of Open Access Journals (Sweden)

    Roozbeh Tanhaeivash

    2016-08-01

    Full Text Available We present the first case study of idiopathic gigantic suprapubic lymphedema and buried penis treated with puboscrotal reconstruction in a patient with initial extreme obesity after an extensive weight reduction (120 kg. Massive localized lymphedema of the suprapubic region should be differentiated from the scrotal type. Severe lymphedema could not resolve on its own and weight reduction does not seem to be helpful in such cases.

  12. NMR study of Albemoschus esculentus characterization

    International Nuclear Information System (INIS)

    Bathista, A.L.B.S; Silva, E.O.; Nogueira, Jose de S.; Tavares, M.I.B.

    2001-01-01

    The investigation of the main compounds presented in the Albemoschus esculentus has been carried out employing nuclear magnetic resonance spectroscopy (NMR), using solution and solid state NMR when it one was necessary. The evaluation of NMR data allowed us to characterize the main type of components presented in this kind of sample. It was necessary to use a total information from solid state NMR and also the solution response. From these information we could get that four main components were presented in this sample. One in the shell, that is cellulose, another one between the shell and seeds that is a polysaccharide and in the seed two components were found one is a starch and the second one is an oil, a triacylglycerol. These components are responsible by its physical chemistry properties. (author)

  13. Characterization of Thai Amulets A PIXE Study

    International Nuclear Information System (INIS)

    Won-In, K.; Suksawang, S.; Intarasiri, S.; Thongleurm, Chom; Kamwanna, T.; Dararutana, P.

    2011-01-01

    The Thai amulets that created in an image of Lord Buddha meditation were made to explain the Dharma of Buddha and believed to bless every life in this world for good karma. Phra Somdej Wat Rakhang amulet is the top of the five most famous Thai amulets. There are many molds with various compositions. In this work, it was the first time that X-ray fluorescence spectrometry methods; scanning electron microscope cooperated with energy dispersive X-ray fluorescence spectrometer (SEM/EDS) and particle induced X-ray emission spectroscopy (PIXE) were carried out to analyze their compositions. Two samples were collected from different molds. Results revealed C, Ca and Si were main composition. The differences in their compositions have been used to identify and characterize for each molds

  14. Synthesis and Characterization Studies of MIL-101

    Directory of Open Access Journals (Sweden)

    Emine Kaya EKİNCİ

    2017-12-01

    Full Text Available MIL-101 is a kind of Metal Organic Frameworks (MOFs, which have attracted much attention in the past decade due to its promising application in chemical industries. MIL-101 is also known as “Porous Chromium Terephthalate”. It has very high surface area and pore volume. MIL-101 exhibits exceptional stability against moisture and other chemicals and is composed of coordinately unsaturated Cr- sites with high concentration available for catalysis and adsorption. MIL-101 was synthesized by hydrothermal method and characterized by XRD, nitrogen adsorption and desorption analyses and SEM. XRD patterns show the presence of MIL-101’s crystal structure with high surface area (~2400 m2/g. Nitrogen adsorption-desorption analyzes showed that the material exhibited mesoporous material behavior.

  15. Case Study Research: Foundations and Methodological Orientations

    Directory of Open Access Journals (Sweden)

    Helena Harrison

    2017-01-01

    Full Text Available Over the last forty years, case study research has undergone substantial methodological development. This evolution has resulted in a pragmatic, flexible research approach, capable of providing comprehensive in-depth understanding of a diverse range of issues across a number of disciplines. Change and progress have stemmed from parallel influences of historical transformations in approaches to research and individual researcher's preferences, perspectives, and interpretations of this design. Researchers who have contributed to the development of case study research come from diverse disciplines with different philosophical perspectives, resulting in a variety of definitions and approaches. For the researcher new to using case study, such variety can create a confusing platform for its application. In this article, we explore the evolution of case study research, discuss methodological variations, and summarize key elements with the aim of providing guidance on the available options for researchers wanting to use case study in their work. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1701195

  16. Collaborative Assessment: Middle School Case Study

    Science.gov (United States)

    Parkison, Paul T.

    2014-01-01

    Utilizing a participant observer research model, a case study of the efficacy of a collaborative assessment methodology within a middle school social studies class was conducted. A review of existing research revealed that students' perceptions of assessment, evaluation, and accountability influence their intrinsic motivation to learn. A…

  17. Case Studies in Library Computer Systems.

    Science.gov (United States)

    Palmer, Richard Phillips

    Twenty descriptive case studies of computer applications in a variety of libraries are presented in this book. Computerized circulation, serial and acquisition systems in public, high school, college, university and business libraries are included. Each of the studies discusses: 1) the environment in which the system operates, 2) the objectives of…

  18. Prader-Willi Disease: A Case Study.

    Science.gov (United States)

    Forbus, William R., III

    A case study focuses on the characteristics and physical management of a 15-year-old with Prader-Willi Syndrome, a birth defect associated with hypotonia, insatiable appetite, hypogonadism, central nervous system dysfunction, and abnormal growth and development . A literature review addresses studies dealing with behavior modification of obesity…

  19. Mining Product Data Models: A Case Study

    Directory of Open Access Journals (Sweden)

    Cristina-Claudia DOLEAN

    2014-01-01

    Full Text Available This paper presents two case studies used to prove the validity of some data-flow mining algorithms. We proposed the data-flow mining algorithms because most part of mining algorithms focuses on the control-flow perspective. First case study uses event logs generated by an ERP system (Navision after we set several trackers on the data elements needed in the process analyzed; while the second case study uses the event logs generated by YAWL system. We offered a general solution of data-flow model extraction from different data sources. In order to apply the data-flow mining algorithms the event logs must comply a certain format (using InputOutput extension. But to respect this format, a set of conversion tools is needed. We depicted the conversion tools used and how we got the data-flow models. Moreover, the data-flow model is compared to the control-flow model.

  20. Cryostat design case studies, principles and engineering

    CERN Document Server

    2016-01-01

    This book enables the reader to learn the fundamental and applied aspects of practical cryostat design by examining previous design choices and resulting cryostat performance. Through a series of extended case studies the book presents an overview of existing cryostat design covering a wide range of cryostat types and applications, including the magnet cryostats that comprise the majority of the Large Hadron Collider at CERN, space-borne cryostats containing sensors operating below 1 K, and large cryogenic liquid storage vessels. It starts with an introductory section on the principles of cryostat design including practical data and equations. This section is followed by a series of case studies on existing cryostats, describing the specific requirements of the cryostat, the challenges involved and the design choices made along with the resulting performance of the cryostat. The cryostat examples used in the studies are chosen to cover a broad range of cryostat applications and the authors of each case are ...

  1. Sibutramine characterization and solubility, a theoretical study

    Science.gov (United States)

    Aceves-Hernández, Juan M.; Nicolás Vázquez, Inés; Hinojosa-Torres, Jaime; Penieres Carrillo, Guillermo; Arroyo Razo, Gabriel; Miranda Ruvalcaba, René

    2013-04-01

    Solubility data from sibutramine (SBA) in a family of alcohols were obtained at different temperatures. Sibutramine was characterized by using thermal analysis and X-ray diffraction technique. Solubility data were obtained by the saturation method. The van't Hoff equation was used to obtain the theoretical solubility values and the ideal solvent activity coefficient. No polymorphic phenomena were found from the X-ray diffraction analysis, even though this compound is a racemic mixture of (+) and (-) enantiomers. Theoretical calculations showed that the polarisable continuum model was able to reproduce the solubility and stability of sibutramine molecule in gas phase, water and a family of alcohols at B3LYP/6-311++G (d,p) level of theory. Dielectric constant, dipolar moment and solubility in water values as physical parameters were used in those theoretical calculations for explaining that behavior. Experimental and theoretical results were compared and good agreement was obtained. Sibutramine solubility increased from methanol to 1-octanol in theoretical and experimental results.

  2. Atomic level characterization in corrosion studies

    Science.gov (United States)

    Marcus, Philippe; Maurice, Vincent

    2017-06-01

    Atomic level characterization brings fundamental insight into the mechanisms of self-protection against corrosion of metals and alloys by oxide passive films and into how localized corrosion is initiated on passivated metal surfaces. This is illustrated in this overview with selected data obtained at the subnanometre, i.e. atomic or molecular, scale and also at the nanometre scale on single-crystal copper, nickel, chromium and stainless steel surfaces passivated in well-controlled conditions and analysed in situ and/or ex situ by scanning tunnelling microscopy/spectroscopy and atomic force microscopy. A selected example of corrosion modelling by ab initio density functional theory is also presented. The discussed aspects include the surface reconstruction induced by hydroxide adsorption and formation of two-dimensional (hydr)oxide precursors, the atomic structure, orientation and surface hydroxylation of three-dimensional ultrathin oxide passive films, the effect of grain boundaries in polycrystalline passive films acting as preferential sites of passivity breakdown, the differences in local electronic properties measured at grain boundaries of passive films and the role of step edges at the exposed surface of oxide grains on the dissolution of the passive film. This article is part of the themed issue 'The challenges of hydrogen and metals'.

  3. Clean Cities Case Study: Barwood Cab Fleet Study Summary

    International Nuclear Information System (INIS)

    Whalen, P.

    1999-01-01

    Barwood Cab Fleet Study Summary is the second in a new series called''Alternative Fuel Information Case Studies,'' designed to present real-world experiences with alternative fuels to fleet managers and other industry stakeholders

  4. Identification and characterization of Department of Energy special-case radioactive waste

    International Nuclear Information System (INIS)

    Williams, R.E.; Kudera, D.E.

    1990-01-01

    This paper identifies and characterizes Department of Energy (DOE) special-case radioactive wastes. Included in this paper are descriptions of the special-case waste categories and their volumes and curie contents, as well as discussions of potential methods for management of these special-case wastes. Work on extensive inventories of DOE-titled special-case waste are still in progress. All radioactive waste is characterized to determine its waste category. Some wastes may have characteristics of more than one of the major waste types. These characteristics may prevent such wastes from being managed as typical high-level, low-level, or transuranic waste. DOE has termed these wastes special-case wastes. Special-case wastes may require special management and disposal schemes. Because of these special considerations, DOE-Headquarters (HQ) required the identification of all existing and potential DOE-owned special case waste to determine future management planning and funding requirements. The inventory effort includes all commercially held, DOE-owned radioactive materials

  5. Repurposing legacy data innovative case studies

    CERN Document Server

    Berman, Jules J

    2015-01-01

    Repurposing Legacy Data: Innovative Case Studies takes a look at how data scientists have re-purposed legacy data, whether their own, or legacy data that has been donated to the public domain. Most of the data stored worldwide is legacy data-data created some time in the past, for a particular purpose, and left in obsolete formats. As with keepsakes in an attic, we retain this information thinking it may have value in the future, though we have no current use for it. The case studies in this book, from such diverse fields as cosmology, quantum physics, high-energy physics, microbiology,

  6. Case studies in atomic collision physics

    CERN Document Server

    McDaniel, E W

    1974-01-01

    Case Studies in Atomic Physics III focuses on case studies on atomic and molecular physics, including atomic collisions, transport properties of electrons, ions, molecules, and photons, interaction potentials, spectroscopy, and surface phenomena. The selection first discusses detailed balancing in the time-dependent impact parameter method, as well as time-reversal in the impact parameter method and coupled state approximation. The text also examines the mechanisms of electron production in ion. Topics include measurement of doubly differential cross sections and electron spectra, direct Coul

  7. [HRCT imaging characterized of congenital abnormalities of the inner ear in 45 cases].

    Science.gov (United States)

    Wang, Jinling; Meng, Meijuan; Huan, Yi; Zhang, Jinsong

    2003-10-01

    To explore the high resolution CT (HRCT) image characterized of congenital abnormalities of the inner ear(CAIE), and its value in the diagnosis and treatment of CAIE. The clinic data and axial HRCT scans of CAIE in 45 cases were analyzed. In 45 CAIE patients, most of them were frequently associated with slowly progressive sensorineural hearing loss in childhood, 15 ears were fluctuating hearing loss. Seventeen ears were unilateral semicircular canal paralysis. HRCT showed that Michel type 3 cases(4 ears), Mondini type 25 cases(39 ears). Large vestibular aqueduct malformation not associated with anomalies of inner ears 13 cases(23 ears), anomalies of internal auditory canal 4 cases (5 ears). Thirteen ears were associated with outer and middle ear malformation. HRCT image has the important value in the diagnosis and treatment of CAIE, especially for the excerpt of indication of cochlear implantation.

  8. Financial Shenanigans : A Case Study in Malaysia

    OpenAIRE

    Ooi, Ki Wei

    2013-01-01

    This study investigates the financial shenanigan cases which subject to the enforcement actions by the Malaysian Securities Commission between 2006 and 2011 for alleged financial misreporting. The scope of this study includes the attempts used, causes and consequences of the financial shenanigans and the post-financial shenanigans recovery plans devised to turnaround the companies. This study finds that the most common attempt used by the sample companies is overstating the revenue, follows b...

  9. Financial Shenanigans : A Case Study of Nigeria

    OpenAIRE

    Onitilo, Nnenna Chidimma

    2015-01-01

    This study investigates the identified cases of financial shenanigans in between 2001 and 2009 in Nigeria. The scope of this study includes the identification of the common attempts and approaches used by companies and the motivations for financial shenanigans. A cross country comparison of the characteristics of the corporate reporting environments between Nigeria and Malaysia was also carried out. This study finds that the most common attempt used by the sample companies are majorly revenue...

  10. Hypnotherapy for persistent genital arousal disorder: a case study.

    Science.gov (United States)

    Elkins, Gary R; Ramsey, Derek; Yu, Yimin

    2014-01-01

    Persistent genital arousal disorder (PGAD) is characterized by intrusive sexual arousal that is unresolvable via sexual activity and persists for an extended period of time. PGAD's etiology is unknown, and it has no established treatments. This case study reports on a 71-year-old female patient diagnosed with PGAD who received 9 sessions of hypnotherapy. The following measures were administered at baseline and follow-up: Hospital Anxiety and Depression Scale, Center for Epidemiologic Studies Depression Scale, Pittsburgh Sleep Quality Index, and visual analogue measurements of quality of life, intensity of symptoms, and marital interference. At follow-up, there were significant improvements in all measures. Given the currently limited alternatives for treatment, this case study suggests that hypnotherapy may be beneficial for some patients with PGAD.

  11. Characterization study of industrial waste glass as starting material ...

    African Journals Online (AJOL)

    In present study, an industrial waste glass was characterized and the potential to assess as starting material in development of bioactive materials was investigated. A waste glass collected from the two different glass industry was grounded to fine powder. The samples were characterized using X-ray fluorescence (XRF), ...

  12. The role of radionuclide studies in emergency cases

    International Nuclear Information System (INIS)

    Nishimura, Tsunehiko; Hayashida, Kohei; Uehara, Toshiisa

    1982-01-01

    Radionuclide studies have been performed popularly because of its noninvasive and simple method recently. In this study, we applied this technique for the evaluation of emergency cases in cardiovascular diseases. There were 93 cases (1.5%) out of 6163 cases, done during 1981. The subjects were 34 cases of cardiac studies (9 cases of sup(99m)Tc-PYP myocardial imaging, 12 cases of thallium myocardial imaging, 13 cases of cardioangiography), 23 cases of peripheral diseases (12 cases of peripheral angiography, 11 cases of venography), 16 cases of pulmonary imaging, 10 cases of renal studies (6 cases of renal angiography, 9 cases of renal imaging) and 5 cases of brain angiography. These studies were proven to be useful clinically for the evaluation of emergency cases and follow-up studies. In the near future, ''emergency radionuclide studies'' would be benefit for the high-risk patients noninvasively. (author)

  13. Characterizing Student Expectations: A Small Empirical Study

    Science.gov (United States)

    Warwick, Jonathan

    2016-01-01

    This paper describes the results of a small empirical study (n = 130), in which undergraduate students in the Business Faculty of a UK university were asked to express views and expectations relating to the study of a mathematics. Factor analysis is used to identify latent variables emerging from clusters of the measured variables and these are…

  14. STUDY OF 200 CASES OF PLEURAL FLUID

    Directory of Open Access Journals (Sweden)

    Ramakrishna R

    2016-09-01

    Full Text Available BACKGROUND We have studied 200 patients of pleural fluid presenting to our tertiary care centre. Presence of cases of pleural fluid is a common presentation both in pulmonary and extrapulmonary diseases. We analysed the patients having both exudates and transudates and studied the results. MATERIALS AND METHODS We selected patients above 20 years of age and classified the patients with pleural fluid as having transudates and exudates. We studied the causes of transudates and exudates. A total of 200 patients are studied in this prospective study. Diagnosis of pleural exudates is made on the basis of Light’s criteria, chest x-ray, pleural fluid analysis, CT scan in selected patients, sputum examination, bronchoscopy and bronchial washings. Moribund and non-cooperative patients and HIV positives were excluded from the study. RESULTS Among the 200 patients, 91% have exudates. 9% have transudates by Light’s criteria. Tuberculosis is the commonest cause of effusions (64.83% followed by malignancy (13.73% and sympneumonic or parapneumonic effusions (9.89%. Pleural effusions occurred predominantly in males. Prevalence of diabetes Mellitus among cases of tuberculous pleural effusions is 13.56%. Tuberculous effusions are predominantly right-sided. CONCLUSION Predominant cases of pleural fluid are exudates. Commonest cause of pleural effusion is Tuberculosis followed by malignancy both pulmonary and extrapulmonary and sym. and parapneumonic effusions. Prevalence of Diabetes among Tuberculous pleural effusion cases is more or less same as in general population. Cough, expectoration fever, chest pain and breathlessness are the common symptoms occurring in three fourths of the patients of tuberculous pleural effusion. Most of the cases of Tuberculous effusion are above 30 years of age. In the diagnosis of tuberculous pleural effusion, Pleural fluid ADA is very important. Pleural fluid cytology, pleural biopsy, bronchoscopy, bronchial washings and sputum

  15. Effective communication. A Platonic case study

    NARCIS (Netherlands)

    Wakker, Gerry C.; Wieling, Martijn; Kroon, Martin; Van Noord, Gertjan

    As a contribution to the valedictory volume for John Nerbonne I present a case study of two thematically similar passages in Plato where I will make use of an analysis based on discourse cohesion and above all on the rhetorical and manipulative use of particles to show how a single (leading)

  16. The Danish National Case Study Report

    DEFF Research Database (Denmark)

    Brodersen, Søsser; Jørgensen, Michael Søgaard

    the projects so it fits into the university schedule, without leaving out the time perspective of the clients, and secure the research is applicable for the clients and based on their need for knowledge. The case studies have shown different roles of a Science Shop. All Science Shops have a role as mediator...

  17. Portfolio Manager Selection – A Case Study

    DEFF Research Database (Denmark)

    Christensen, Michael

    2017-01-01

    Within a delegated portfolio management setting, this paper presents a case study of how the manager selection process can be operationalized in practice. Investors have to pursue a thorough screening of potential portfolio managers in order to discover their quality, and this paper discusses how...

  18. Acoustical case studies of three green buildings

    Science.gov (United States)

    Siebein, Gary; Lilkendey, Robert; Skorski, Stephen

    2005-04-01

    Case studies of 3 green buildings with LEED certifications that required extensive acoustical retrofit work to become satisfactory work environments for their intended user groups will be used to define areas where green building design concepts and acoustical design concepts require reconciliation. Case study 1 is an office and conference center for a city environmental education agency. Large open spaces intended to collect daylight through clerestory windows provided large, reverberant volumes with few acoustic finishes that rendered them unsuitable as open office space and a conference room/auditorium. Case Study 2 describes one of the first gold LEED buildings in the southeast whose primary design concepts were so narrowly focused on thermal and lighting issues that they often worked directly against basic acoustical requirements resulting in sound levels of NC 50-55 in classrooms and faculty offices, crosstalk between classrooms and poor room acoustics. Case study 3 is an environmental education and conference center with open public areas, very high ceilings, and all reflective surfaces made from wood and other environmentally friendly materials that result in excessive loudness when the building is used by the numbers of people which it was intended to serve.

  19. Advanced supplier partnership practices: a case study.

    Science.gov (United States)

    Williams, B R

    2000-05-01

    This article describes how a supplier partnership was set up to avoid the typical purchasing relationship--price being inversely proportional to quantity and having the purchaser take all the risk of product obsolescence. The case study also describes how rate-based replenishment replaced time-based delivery, and how all these advantages were achieved at reduced administrative costs.

  20. Management in Virtual Environments. Case Studies

    OpenAIRE

    Mazurek, Grzegorz; Gembicki, Michał; Krzemień, Grzegorz; Przegalińska, Aleksandra K.; Starostka, Justyna; Skorulska, Karolina; Prystupa-Rządca, Kaja

    2015-01-01

    The following publication consists of 12 case studies, which encompass various aspects of the ICT impact on contemporary businesses, focusing – among other things – on such concepts as: crowdsourcing, the internet of things, design thinking, digital entertainment, e-commerce, online and off-line distribution or social media marketing. EEA, Norway Grants Anna Goryńska

  1. Teaching Business Intelligence through Case Studies

    Science.gov (United States)

    Pomykalski, James J.

    2015-01-01

    In teaching business students about the application and implementation of technology, especially involving business intelligence, it is important to discover that project success in enterprise systems development efforts often depend on the non-technological problems or issues. The focus of this paper will be on the use of multiple case studies in…

  2. Business Registration Reform Case Studies : Malaysia

    OpenAIRE

    Olaisen, John

    2009-01-01

    This collection of case studies describes experiences and draws lessons from varied business registration reform programs in economies in vastly different stages of development: Bulgaria, Estonia, Ireland, Madagascar, and Malaysia. Over the last twenty years, a number of countries have recognized the importance of smooth and efficient business start up procedures. A functioning business re...

  3. Predicting students drop out : a case study

    NARCIS (Netherlands)

    Dekker, G.W.; Pechenizkiy, M.; Vleeshouwers, J.M.; Barnes, T.; Desmarais, M.; Romero, C.; Ventura, S.

    2009-01-01

    The monitoring and support of university freshmen is considered very important at many educational institutions. In this paper we describe the results of the educational data mining case study aimed at predicting the Electrical Engineering (EE) students drop out after the first semester of their

  4. WP6 - The Ag2020 Case Studies

    DEFF Research Database (Denmark)

    Hansen, Jens G; Borch, Kristian; Trombi, Giacomo

    2010-01-01

    of the Future are presented. Finally, in section 1.4, is described the structure of the present report,which is firmly followed by the four case studies involved in the Project, namely the Rhodope Mountainous region in Bulgaria (CS1), The Kastelli region (Herakleion nomos) in Greece (CS2), the Central Denmark...

  5. case study of ramat park benin city

    African Journals Online (AJOL)

    user

    SETTLEMENT: CASE STUDY OF RAMAT PARK BENIN CITY. E. S. Okonofua1, R. ... region on a daily basis. The movement of ... with major road networks [2]. In order to ease ... led to series of research and development of traffic noise models.

  6. CASE STUDY – HIV AND LUNG DISEASE

    African Journals Online (AJOL)

    2011-04-02

    Apr 2, 2011 ... pathology deep to the paraseptal bullae. An intercostal drain tip is seen in the left lateral pleural space. Fig. 2. Axial computed tomography scan on lung windows. Large bilateral paraseptal bullae are demonstrated with residual antero-medial pneumothorax. 37. CASE STUDY – HIV AND LUNG DISEASE ...

  7. A Case Study of the Vredefort Dome

    African Journals Online (AJOL)

    South Africa became a signatory to and ratified the World Heritage Convention, 1972 (WHC) in 1997. It thereby voluntarily agreed to identify and conserve world heritage areas of universal value for the benefit of mankind. This article presents a case study of the Vredefort Dome, one of South Africa\\'s World Heritage Sites ...

  8. Climate wise case study compendium: Report 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    This case study compendium is one of several Climate Wise tools available to help interested companies identify cost-effective options. Climate Wise, a private-public partnership program, is a key Federal initiative to return greenhouse gas emissions to 1990 levels by 2000.

  9. Making Professional Development Flexible: A Case Study.

    Science.gov (United States)

    Forsyth, Rachel

    2002-01-01

    Presents a case study of an online course that was designed for staff professional development at Manchester Metropolitan University (United Kingdom). Discusses the flexibility of online courses; course design; activities for short online workshops; evaluation methods for course evaluation; and results of participant questionnaires. (LRW)

  10. Library Virtual Tours: A Case Study

    Science.gov (United States)

    Ashmore, Beth; Grogg, Jill E.

    2004-01-01

    Virtual tours delivered via the Web have become a common tool for both instruction and outreach. This article is a case study of the creation of a virtual tour for a university library and is intended to provide others interested in creating a virtual tour of their library the opportunity to learn from the mistakes and successes of fellow…

  11. Learning Machine Learning: A Case Study

    Science.gov (United States)

    Lavesson, N.

    2010-01-01

    This correspondence reports on a case study conducted in the Master's-level Machine Learning (ML) course at Blekinge Institute of Technology, Sweden. The students participated in a self-assessment test and a diagnostic test of prerequisite subjects, and their results on these tests are correlated with their achievement of the course's learning…

  12. Firefighter Workplace Learning: An Exploratory Case Study

    Science.gov (United States)

    Tracey, Edward A.

    2014-01-01

    Despite there being a significant amount of research investigating workplace learning, research exploring firefighter workplace learning is almost nonexistent. The purpose of this qualitative multi-case study was to explore how firefighters conceptualize, report, and practice workplace learning. The researcher also investigated how firefighters…

  13. Spicy Stonehenge : Proposing a SOA Case Study

    NARCIS (Netherlands)

    Espinha, T.A.; Chen, C.; Zaidman, A.E.; Gross, H.G.

    2012-01-01

    Prepint of paper published in: ICSE Workshop on Principles of Engineering Service Oriented Systems (PESOS), 4 June 2012; doi:10.1109/PESOS.2012.6225940 Maintenance research in the context of Service Oriented Architecture (SOA) is currently lacking a suitable standard case study that can be used by

  14. Collegiality in education: a case study

    African Journals Online (AJOL)

    Erna Kinsey

    This case study therefore investigated the effects of a collegial management style on teaching and learning ... resources cannot solely guarantee success at matriculation level. ... vily on school principals, their management teams and the governing .... may be necessary to employ the notion of building with a new member.

  15. It's Not Funny: A Case Study

    Science.gov (United States)

    Méndez-Morse, Sylvia

    2015-01-01

    This case study may be used with personnel supervision, school law, and other school leadership courses. It describes the behavior and actions of one teacher toward another. Student discussions can focus on supervision, workplace mobbing, workplace bullying, as well as sexual harassment. Students should focus on a school leader's role in such…

  16. Teaching the Holocaust through Case Study

    Science.gov (United States)

    Misco, Thomas

    2009-01-01

    This article responds to the curricular challenges teachers face with Holocaust education, including cursory treatments and a lack of focus on individual experiences. First, the author argues for a case-study approach to help students reengage concrete and complex features of the Holocaust as a point of departure for subsequent inquiry. In…

  17. A case study of Florida Road, Durban

    African Journals Online (AJOL)

    2006-06-29

    Jun 29, 2006 ... planning in mixed-use precincts: A case study of .... Technology, Faculty of Engineering and the Built Environment, Department of Town and Regional .... development process of contemporary cities. The origins of this realisation .... financing, and a lack of collaboration .... surrounded by a transport network,.

  18. Nanomaterial Case Studies: Nanoscale Titanium Dioxide ...

    Science.gov (United States)

    This draft document presents two case studies of nanoscale titanium dioxide (nano-TiO2) used (1) to remove arsenic from drinking water and (2) as an active ingredient in topical sunscreen. The draft case studies are organized around a comprehensive environmental assessment approach that combines a product life cycle framework with the risk assessment paradigm. The document does not draw conclusions about potential risks. Rather, the case studies are intended to help identify what needs to be known in order to conduct a comprehensive environmental assessment of the potential risks related to nano-TiO2. This draft document is part of a process that will inform the development of EPA’s research strategy to support nanomaterial risk assessments. The complex properties of various nanomaterials make evaluating them in the abstract or with generalizations difficult if not impossible. Thus, this document focuses on two specific uses of nano-TiO2, as a drinking water treatment and as topical sunscreen. These case studies do not represent completed or even preliminary assessments; rather, they present the structure for identifying and prioritizing research needed to support future assessments.

  19. Characterisation and comparison of case study findings

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard; Dorland, Jens; Pel, Bonno

    2015-01-01

    This report gives an overview and a comparative analysis of the findings from the 12 first case study reports in TRANSIT about aspects of transformative social innovation (TSI). Each of the 12 reports, on which the report is based, includes an analysis of a transnational social innovation network...

  20. Hydrocarbon storage caverns overhaul: A case study

    Energy Technology Data Exchange (ETDEWEB)

    McDougall, N. [Bayer Inc., Sarnia, ON (Canada)

    1998-09-01

    Case studies of four hydrocarbon storage cavern overhauls by Bayer Inc., of Sarnia during the period 1993 to 1997 were reviewed and the lessons learned were discussed. Discussions included inspection requirements for each of the caverns, the logistics and planning plant production around the cavern outages, site and cavern preparation, including removal of the casing slips from the well heads. It was emphasized that cavern overhauls can be expensive operations, unless preceded by proper planning. The largest variable cost is likely to be rig time at about $ 2,000 per day. Planning for the unexpected with thoughtful contingencies can reduce costs and avoid expensive delays.

  1. Characterization of hydrometeors in Sahelian convective systems with an X-band radar and comparison with in situ measurements. Part I : Sensitivity of polarimetric radar particle identification retrieval and case study evaluation

    OpenAIRE

    Cazenave, Frédéric; Gosset, Marielle; Kacou, M.; Alcoba, M.; Fontaine, E.; Duroure, C.; Dolan, B.

    2016-01-01

    The particle identification scheme developed by Dolan and Rutledge for X-band polarimetric radar is tested for the first time in Africa and compared with in situ measurements. The data were acquired during the Megha-Tropiques mission algorithm-validation campaign that occurred in Niger in 2010. The radar classification is compared with the in situ observations gathered by an instrumented aircraft for the 13 August 2010 squall-line case. An original approach has been developed for the radar-in...

  2. Synthesis across social innovation case studies

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard; Avelino, Flor; Dorland, Jens

    2016-01-01

    Part 1 is an overview and a comparative analysis of the findings from the 20 case study reports in TRANSIT about aspects of transformative social innovation (TSI). Each of the 20 reports, which the report is based on, includes an analysis of a transnational social innovation network and at least...... two local social innovation initiatives. Part 2 consists of extended abstracts of 8 papers which either focus on empirical phenomena surfacing in different TRANSIT cases (e.g. alternative economic arrangements), take a societal or methodological issue as starting point (e.g. inclusivity or research...... relations), address propositions from TRANSIT proto-theory (institutionalization dialectics, responses to crisis), build upon thematic clusters used for case selection (e.g. spaces for/of innovation, inclusive society, new economy, transformative science) or inductively develop specific sensitizing concepts...

  3. Case studies on selected natural food antioxidants

    OpenAIRE

    Herrero, Miguel; Mendiola, J. A.; Cifuentes, Alejandro; Ibáñez, Elena

    2013-01-01

    In this chapter, a broad description of several case studies related to common antioxidants found in food-related products is presented. In this regard, special attention is put on the novel advanced environmentally-friendly extraction methods nowadays employed to extract and purify those potent antioxidants from natural matrices. A brief description of these extraction processes is provided together with some of the instrumentation needed. Besides, the studies carried out so f...

  4. Tisettanta case study: the interoperation of furniture production companies

    Science.gov (United States)

    Amarilli, Fabrizio; Spreafico, Alberto

    This chapter presents the Tisettanta case study, focusing on the definition of the possible innovations that ICT technologies can bring to the Italian wood-furniture industry. This sector is characterized by industrial clusters composed mainly of a few large companies with international brand reputations and a large base of SMEs that manufacture finished products or are specialized in the production of single components/processes (such as the Brianza cluster, where Tisettanta operates). In this particular business ecosystem, ICT technologies can bring relevant support and improvements to the supply chain process, where collaborations between enterprises are put into action through the exchange of business documents such as orders, order confirmation, bills of lading, invoices, etc. The analysis methodology adopted in the Tisettanta case study refers to the TEKNE Methodology of Change (see Chapter 2), which defines a framework for supporting firms in the adoption of the Internetworked Enterprise organizational paradigm.

  5. 216-Z-8 French drain characterization study

    International Nuclear Information System (INIS)

    Marratt, M.C.; Kasper, R.B.; Van Luik, A.E.

    1984-09-01

    The 216-Z-8 French drain study is one of a series of studies examining historical transuranic waste facilities no longer in use at the Hanford Site. The 216-Z-8 French drain underground disposal system consisted of a large settling tank that overflowed into a French drain. The French drain consisted of two large-diameter, gravel filled, vitrified clay pipes placed on end, end-to-end, over a gravel-filled excavation. The top of the drain was sealed with concrete to prevent the upward flow of waste solution. The waste solution discharged to the 216-Z-8 waste disposal system was a neutralized, transuranic recovery process, filter cake, backflush slurry. The primary objective of this study was to determine the distribution of plutonium and americium beneath the French drain. Transuranic activity under the French drain did not exceed 5 nCi/g in the soil samples obtained from a well within 1 m of the drain structure. Conservative estimates indicated that 4 to 5 m 3 of radioactive contaminated sediments, 10 nCi/g may lie directly under the 216-Z-8 French drain. The secondary objective of the study was to evaluate the possibility of a leak in the settling tank. Results from the analysis of soil samples from wells drilled around the settling tank indicated the presence of low-level transuranic contamination (on the order of 0.001 nci/g) in the soil surrounding the tank. However, the distribution of the contamination does not support a leak as a plausible mechanism to account for the observed activity surrounding the tank. The bulk of the plutonium was confirmed to be in the sludge that remained in the tank; thus, no significant environmental impact would be expected even if there has been a leak

  6. On robust analysis of paycheck: case study

    Directory of Open Access Journals (Sweden)

    Michal Uherek

    2011-01-01

    Full Text Available Many statistical tests are constructed to check the validity of normal distribution. Here we propose a case study on analysis of paycheck where we employ the RT class of tests for normality firstly introduced in Střelec, Stehlík (2008. In particular such a study can be of interest for pension funds theoreticians and practitioners, which study the transitions of pension systems from one social security state to the another one. Our study illustrates some possible distributional deviations of salary residuals on a real data.

  7. Synthesis, characterization and antimicrobial studies of bio silica ...

    Indian Academy of Sciences (India)

    2018-05-16

    May 16, 2018 ... Cynodon dactylon; green approach; silica nanoparticles; characterization; antimicrobial studies. 1. .... The obtained powder was well-ground with a mortar and ..... Inhalation of SiCl4 fumes irritates nose, throat and lungs.

  8. Vitiligo: A study of 120 cases

    Directory of Open Access Journals (Sweden)

    Kar P

    2001-11-01

    Full Text Available Vitiligo is a common pignientary disorder and of major social and cosmetic concern in India. Purpose of the study was to find out age at onset and sex incidence in vitiligo, role of hereditary factors and associations with other diseases. 120 self reporting vitiligo patients attending out patient department of a service hospital were selected for the study and this data was analysed. In the present series out of 120 cases 62 (51.6% were males and 58(48.35%were females. There was practically no difference in sex incidence. The lowest age of onset was two years and the oldest was 65 years. In the majority of patients,52(43.2%, disease started before twenty years of age.8 (6.6% cases gave definite family history of vitiligo. Exposed areas of the body were commonly affected in majority (66.6% of cases. The legs were commonest site of involvement in 60(50% cases. Circunicript type of vitiligo (46.6% was heading the list. Majority of patients (56.6% had multiple lesions. Diabetes mellitus was found in 2 (2.6% patients. Cause of vitiligo is still idiopathic. Hereditary factors hardly play any role in manifestation of vitiligo

  9. CASE STUDY ON RE-ADJUSTMENTS DEPENDING ON PRICE MODIFICATION

    Directory of Open Access Journals (Sweden)

    Cozma Ighian Diana

    2011-01-01

    Full Text Available Inflationary moments, characterized by significant price rises, have proved that accountingsystems based on historical costs provide a distorted image of the reality: the elements ofthe balance sheet are under-valuated, and the stock-related expenses and amortization in theprofit and loss account are also under-valuated. Under these circumstances, the result isover-valuated, and its distribution leads to allotments from the company’s capital. In thispaper we draw up a case study with regards to the methods used for adjusting pricemodification, clearly outlining, through a comparative analysis, the main differencesbetween the accounting system based on historical cost and inflation accounting.

  10. A case study in bifurcation theory

    Science.gov (United States)

    Khmou, Youssef

    This short paper is focused on the bifurcation theory found in map functions called evolution functions that are used in dynamical systems. The most well-known example of discrete iterative function is the logistic map that puts into evidence bifurcation and chaotic behavior of the topology of the logistic function. We propose a new iterative function based on Lorentizan function and its generalized versions, based on numerical study, it is found that the bifurcation of the Lorentzian function is of second-order where it is characterized by the absence of chaotic region.

  11. Rigour in qualitative case-study research.

    Science.gov (United States)

    Houghton, Catherine; Casey, Dympna; Shaw, David; Murphy, Kathy

    2013-03-01

    To provide examples of a qualitative multiple case study to illustrate the specific strategies that can be used to ensure the credibility, dependability, confirmability and transferability of a study. There is increasing recognition of the valuable contribution qualitative research can make to nursing knowledge. However, it is important that the research is conducted in a rigorous manner and that this is demonstrated in the final research report. A multiple case study that explored the role of the clinical skills laboratory in preparing students for the real world of practice. Multiple sources of evidence were collected: semi-structured interviews (n=58), non-participant observations at five sites and documentary sources. Strategies to ensure the rigour of this research were prolonged engagement and persistent observation, triangulation, peer debriefing, member checking, audit trail, reflexivity, and thick descriptions. Practical examples of how these strategies can be implemented are provided to guide researchers interested in conducting rigorous case study research. While the flexible nature of qualitative research should be embraced, strategies to ensure rigour must be in place.

  12. Epidemiological characterization of oral cancer. Study Protocol.

    Directory of Open Access Journals (Sweden)

    Alejandra Fernández

    2015-04-01

    Full Text Available Oral cancer is a disease of high impact globally. It ranks as the sixth more frequent one among all types of cancer. In spite of being a widely known pathology and easy access to the diagnosis, the lack of epidemiological data reported in the last 10 years in Chile called attention to. At the global level, the World Health Organization (WHO has developed a project called “GLOBOCAN” in order to collect epidemiological data of the global cancer, between its data, highlights the high incidence and high rate of mortality in the male sex, parameter that shows tendency to replicate in both America and Chile. In consequence to these data, a narrative review of the literature concerning the epidemiological profile of the different forms of oral cancer in the past 15 years was done. The diagnosis of oral cancer crosses transversely the Dental Science, forcing us to establish triads of work between oral and maxillofacial surgeons, pathologists and dentists of the various specialties, so as to allow a timely research, appropriate biopsies and histopathological studies finishes with the purpose of, on the one hand, obtain timely and accurate diagnostics, in addition, maintaining the epidemiological indicators.

  13. The Pendulum A Case Study in Physics

    CERN Document Server

    Baker, Gregory L

    2005-01-01

    The pendulum: a case study in physics is a unique book in several ways. Firstly, it is a comprehensive quantitative study of one physical system, the pendulum, from the viewpoint of elementary and more advanced classical physics, modern chaotic dynamics, and quantum mechanics. In addition, coupled pendulums and pendulum analogs of superconducting devices are also discussed. Secondly, this book treats the physics of the pendulum within a historical and cultural context,showing, for example, that the pendulum has been intimately connected with studies of the earth's density, the earth's motion,

  14. The Glioma International Case-Control Study

    DEFF Research Database (Denmark)

    Amirian, E. Susan; Armstrong, Georgina N; Zhou, Renke

    2016-01-01

    Decades of research have established only a few etiological factors for glioma, which is a rare and highly fatal brain cancer. Common methodological challenges among glioma studies include small sample sizes, heterogeneity of tumor subtypes, and retrospective exposure assessment. Here, we briefly...... describe the Glioma International Case-Control (GICC) Study (recruitment, 2010-2013), a study being conducted by the Genetic Epidemiology of Glioma International Consortium that integrates data from multiple data collection sites, uses a common protocol and questionnaire, and includes biospecimen...

  15. Case studies of nurseries in Malawi

    DEFF Research Database (Denmark)

    Namoto, M.; Likoswe, M.G.

    This study of 42 case studies of nurseries was made as part of a major sample survey of 360 nurseries in 6 districts in Malawi. The purpose of the study was to let the small nurseries in the country explain in their own words how they source seed, how and for whom they produce seedlings......, and to explain about their problems and opportunities in the nursery business. The assessment was made within the framework of Improved Seed Supply for Agroforestry in African Countries (ISSAAC), a Danida supported programme implemented in cooperation between Forest & Landscape Denmark and World Agroforestry...

  16. ["Nervous breakdown": a diagnostic characterization study].

    Science.gov (United States)

    Salmán, E; Carrasco, J L; Liebowitz, M; Díaz Marsá, M; Prieto, R; Jusino, C; Cárdenas, D; Klein, D

    1997-01-01

    An evaluation was made of the influence of different psychiatric co-morbidities on the symptoms of the disorder popularly known as "ataque de nervios" (nervous breakdown) among the US Hispanic population. Using a self-completed instrument designed specially for both traditional nervous breakdown and for panic symptoms, and structured or semi-structured psychiatric interviews for Axis I disorders, and evaluation was made of Hispanic subjects who sought treatment for anxiety in a clinic (n = 156). This study centered on 102 subjects who presented symptoms of "nervous breakdown" and comorbidity with panic disorder, other anxiety disorders, or affective disorder. Variations in co-morbidity with "nervous breakdown" enabled the identification of different patterns of "nervous breakdown" presenting symptoms. Individuals with "nervous breakdown" and panic disorder characteristically expressed a greater sense of asphyxiation, fear of dying, and growing fear (panic-like) during their breakdowns. Subjects with "nervous breakdown" and affective disorder had a greater sensation of anger and more tendency toward screaming and aggressive behavior such as breaking things during the breakdown (emotional anger). Finally, subjects with "nervous breakdown" and co-morbidity with another anxiety disorder had fewer "paniclike" or "emotional anger" symptoms. These findings suggest that: a) the widely used term "nervous breakdown" is a popular label for different patterns of loss of emotional control; b) the type of loss of emotional control is influenced by the associated psychiatric disorder; and c) the symptoms characteristics of the "nervous breakdown" can be useful clinical markers for associated psychiatric disorders. Future research is needed to determine whether the known Hispanic entity "ataque de nervios" is simply a popular description for different aspects of well-known psychiatric disorders, or if it reflects specific demographic, environmental, personality and/or clinical

  17. Management & Communication: Project Management Case Study

    CERN Multimedia

    Nathalie Dumeaux

    2004-01-01

    We are pleased to announce the recent launch of a new workshop on Project Management. This is designed for People with budgetary, scheduling and/or organizational responsibilities in a project or a sub-project. The objectives through a management case study specially suited to CERN are: to become familiar with modern management techniques in use for structuring, planning, scheduling, costing and progress monitoring of a project or a sub-project. to understand in-depth issues associated with Deliverable-oriented Project Management, Earned Value Management, Advanced Project Cost Engineering and Project Risk Management. The full description of this workshop can be found here. The next session will be held on 8 October 2004. If you are interested in this workshop, please contact Nathalie Dumeaux, email or 78144. Programme of Seminars October to December 2004 Situation : 21.09.2004 Séminaires bilingues Dates Jours Places disponibles Project Management Case study 8 October 1 oui Intr...

  18. Marketing and clinical trials: a case study

    Directory of Open Access Journals (Sweden)

    Entwistle Vikki A

    2007-11-01

    Full Text Available Abstract Background Publicly funded clinical trials require a substantial commitment of time and money. To ensure that sufficient numbers of patients are recruited it is essential that they address important questions in a rigorous manner and are managed well, adopting effective marketing strategies. Methods Using methods of analysis drawn from management studies, this paper presents a structured assessment framework or reference model, derived from a case analysis of the MRC's CRASH trial, of 12 factors that may affect the success of the marketing and sales activities associated with clinical trials. Results The case study demonstrates that trials need various categories of people to buy in – hence, to be successful, trialists must embrace marketing strategies to some extent. Conclusion The performance of future clinical trials could be enhanced if trialists routinely considered these factors.

  19. Marketing and clinical trials: a case study.

    Science.gov (United States)

    Francis, David; Roberts, Ian; Elbourne, Diana R; Shakur, Haleema; Knight, Rosemary C; Garcia, Jo; Snowdon, Claire; Entwistle, Vikki A; McDonald, Alison M; Grant, Adrian M; Campbell, Marion K

    2007-11-20

    Publicly funded clinical trials require a substantial commitment of time and money. To ensure that sufficient numbers of patients are recruited it is essential that they address important questions in a rigorous manner and are managed well, adopting effective marketing strategies. Using methods of analysis drawn from management studies, this paper presents a structured assessment framework or reference model, derived from a case analysis of the MRC's CRASH trial, of 12 factors that may affect the success of the marketing and sales activities associated with clinical trials. The case study demonstrates that trials need various categories of people to buy in - hence, to be successful, trialists must embrace marketing strategies to some extent. The performance of future clinical trials could be enhanced if trialists routinely considered these factors.

  20. Dengue type 4 in Rio de Janeiro, Brazil: case characterization following its introduction in an endemic region.

    Science.gov (United States)

    Heringer, Manoela; Souza, Thiara Manuele A; Lima, Monique da Rocha Q; Nunes, Priscila Conrado G; Faria, Nieli Rodrigues da C; de Bruycker-Nogueira, Fernanda; Chouin-Carneiro, Thaís; Nogueira, Rita Maria R; Dos Santos, Flavia Barreto

    2017-06-09

    Due to the populations' susceptibility, DENV-4 introduction in 2010 led to the occurrence of explosive epidemics in the following years in Brazil. In 2011, DENV-4 was identified in Rio de Janeiro (RJ) and it was prevalent in 2012 and 2013. Here, we aimed to characterize clinical, epidemiological and laboratorial aspects of DENV-4 cases after this serotype introduction in an endemic scenario. Dengue suspected cases (n = 3727) were received and analyzed from January 2011 to December 2013, during outbreaks occurred in RJ, Brazil. Samples were submitted to virological, serological and molecular methods for case confirmation. DENV-4 cases (n = 705) were characterized according to the type of infection, disease severity and, viremia levels and NS1 antigenemia were accessed. Representative strains were partial sequenced for genotyping. DENV-4 was identified in 44.2% (705/1593) of dengue positive cases, virus isolated in 48.7% of the cases. Anti-DENV IgM was detected in 39.4% of the cases, however an increased detection was observed in cases with ≥4 days of symptoms (57.0%). NS1 antigen was identified in 41.5% of DENV-4 cases however, after immune complexes dissociation, the detection significantly increased (87.6%). Females were more affected than males, so did children aged 11-15 years old. Primary cases were more frequently observed than secondary ones and most of them were classified as dengue. No differences on NS1 antigenemia and viraemia within the groups were observed. Despite the higher frequency of severe disease on individuals >65 years old, no differences were observed among the groups and type of infection. However, DENV-4 fatal cases were more frequent on secondary infections (57.1%). DENV-4 Genotype II was identified with a probable origin from Venezuela and Colombia. It has been shown that laboratorial diagnosis is still a reliable tool for the disease surveillance, detecting and confirming emerging epidemics. Despite the occurrence of secondary

  1. Macroprudential Insurance Regulation: A Swiss Case Study

    Directory of Open Access Journals (Sweden)

    Philippe Deprez

    2016-12-01

    Full Text Available This article provides a case study that analyzes national macroprudential insurance regulation in Switzerland. We consider an insurance market that is based on data from the Swiss private insurance industry. We stress this market with several scenarios related to financial and insurance risks, and we analyze the resulting risk capitals of the insurance companies. This stress-test analysis provides insights into the vulnerability of the Swiss private insurance sector to different risks and shocks.

  2. Macroprudential Insurance Regulation: A Swiss Case Study

    OpenAIRE

    Philippe Deprez; Mario V. Wüthrich

    2016-01-01

    This article provides a case study that analyzes national macroprudential insurance regulation in Switzerland. We consider an insurance market that is based on data from the Swiss private insurance industry. We stress this market with several scenarios related to financial and insurance risks, and we analyze the resulting risk capitals of the insurance companies. This stress-test analysis provides insights into the vulnerability of the Swiss private insurance sector to different risks and sho...

  3. Concentrated Photo Voltaics (CPV: a case study

    Directory of Open Access Journals (Sweden)

    Centro S.

    2015-01-01

    Full Text Available Concentrated PhotoVoltaic (CPV, among green energy solutions, nowadays has the ambition to reach grid-parity without subside. CPV substitutes large areas of expensive semiconductor solar cells, with concentrating optics made of cheap materials. Moreover the cells that are suitable for CPV exhibits an unprecedented efficiency and their technology is progressing every year. A case study project, TwinFocus®, will be presented in detail.

  4. Prototype Development and Redesign: A Case Study

    Science.gov (United States)

    1990-03-01

    deal with difficult problems of leadership , strategy and management." [Ref. 10:p. 1] Admiral Turner feels that using the case study method "will help...placement officer was a Lieutenant Commander or Commander. Often times they came from leadership positions of executive officer equivalence. They were...ting power. Personnel within the computer organizatin who are used to manual methods and potential users of the system are resisting the change and

  5. Marketing and clinical trials: a case study

    OpenAIRE

    Entwistle Vikki A; Snowdon Claire; Garcia Jo; Knight Rosemary C; Shakur Haleema; Elbourne Diana R; Roberts Ian; Francis David; McDonald Alison M; Grant Adrian M; Campbell Marion K

    2007-01-01

    Abstract Background Publicly funded clinical trials require a substantial commitment of time and money. To ensure that sufficient numbers of patients are recruited it is essential that they address important questions in a rigorous manner and are managed well, adopting effective marketing strategies. Methods Using methods of analysis drawn from management studies, this paper presents a structured assessment framework or reference model, derived from a case analysis of the MRC's CRASH trial, o...

  6. Private power financing: a case study

    International Nuclear Information System (INIS)

    Stocker, Albert

    1991-01-01

    The Public Utility Regulatory Power Act (PURPA) in the USA and the UK's Electricity Act passed in 1989 are discussed and the first UK private power project is considered. A case study is presented, and covers the questions of when to approach the bank; banker versus investment bank; project fundamentals; the sponsor and the management team; the strength of the key project agreements; syndication of the project debt; and bank support during construction and operation. (author)

  7. Shuttle Transportation System Case-Study Development

    Science.gov (United States)

    Ransom, Khadijah

    2012-01-01

    A case-study collection was developed for NASA's Space Shuttle Program. Using lessons learned and documented by NASA KSC engineers, analysts, and contractors, decades of information related to processing and launching the Space Shuttle was gathered into a single database. The goal was to provide educators with an alternative means to teach real-world engineering processes and to enhance critical thinking, decision making, and problem solving skills. Suggested formats were created to assist both external educators and internal NASA employees to develop and contribute their own case-study reports to share with other educators and students. Via group project, class discussion, or open-ended research format, students will be introduced to the unique decision making process related to Shuttle missions and development. Teaching notes, images, and related documents will be made accessible to the public for presentation of Space Shuttle reports. Lessons investigated included the engine cutoff (ECO) sensor anomaly which occurred during mission STS-114. Students will be presented with general mission infom1ation as well as an explanation of ECO sensors. The project will conclude with the design of a website that allows for distribution of information to the public as well as case-study report submissions from other educators online.

  8. Characterization of mitochondrial proteome in a severe case of ETF-QO deficiency.

    Science.gov (United States)

    Rocha, H; Ferreira, R; Carvalho, J; Vitorino, R; Santa, C; Lopes, L; Gregersen, N; Vilarinho, L; Amado, F

    2011-12-10

    Multiple acyl-CoA dehydrogenase deficiency (MADD) is a mitochondrial fatty acid oxidation disorder caused by mutations that affect electron transfer flavoprotein (ETF) or ETF:ubiquinone oxidoreductase (ETF-QO) or even due to unidentified disturbances of riboflavin metabolism. Besides all the available data on the molecular basis of FAO disorders, including MADD, the pathophysiological mechanisms underlying clinical phenotype development, namely at the mitochondrial level, are poorly understood. In order to contribute to the elucidation of these mechanisms, we isolated mitochondria from cultured fibroblasts, from a patient with a severe MADD presentation due to ETF-QO deficiency, characterize its mitochondrial proteome and compare it with normal controls. The used approach (2-DE-MS/MS) allowed the positive identification of 287 proteins in both patient and controls, presenting 35 of the significant differences in their relative abundance. Among the differentially expressed are proteins associated to binding/folding functions, mitochondrial antioxidant enzymes as well as proteins associated to apoptotic events. The overexpression of chaperones like Hsp60 or mitochondrial Grp75, antioxidant enzymes and apoptotic proteins reflects the mitochondrial response to a complete absence of ETF-QO. Our study provides a global perspective of the mitochondrial proteome plasticity in a severe case of MADD and highlights the main molecular pathways involved in its pathogenesis. Copyright © 2011 Elsevier B.V. All rights reserved.

  9. Report: new guidelines for characterization of municipal solid waste: the Portuguese case.

    Science.gov (United States)

    da Graça Madeira Martinho, Maria; Silveira, Ana Isabel; Fernandes Duarte Branco, Elsa Maria

    2008-10-01

    This report proposes a new set of guidelines for the characterization of municipal solid waste. It is based on an analysis of reference methodologies, used internationally, and a case study of Valorsul (a company that handles recovery and treatment of solid waste in the North Lisbon Metropolitan Area). In particular, the suggested guidelines present a new definition of the waste to be analysed, change the sampling unit and establish statistical standards for the results obtained. In these new guidelines, the sampling level is the waste collection vehicle and contamination and moisture are taken into consideration. Finally, focus is on the quality of the resulting data, which is essential for comparability of data between countries. These new guidelines may also be applicable outside Portugal because the methodology includes, besides municipal mixed waste, separately collected fractions of municipal waste. They are a response to the need for information concerning Portugal (e.g. Eurostat or OECD inquiries) and follow European Union municipal solid waste management policies (e.g. packaging waste recovery and recycling targets and the reduction of biodegradable waste going to landfill).

  10. Physicochemical characterization of pigments and supports in mural paints: Mayapan, Yucatan case

    International Nuclear Information System (INIS)

    Silva V, Y.; Peraza L, C.A.; Bautista M, J.P.; Arenas A, J.

    2006-01-01

    The present work is focused in the study of pigments and supports located in mural paintings belonging to the archaeological site of Mayapan. The raw materials utilized by the pre hispanic are revealed by means of the use of different techniques of characterization such as Scanning and Transmission Electron Microscopy (SEM and TEM, respectively), Energy Dispersive X-Ray Spectroscopy (EDS), X-Ray Diffraction and Fourier Transform Infrared Spectroscopy (FTIR). The pigments analyzed cover the following colors: yellow, blue, white, orange, black, red, olive and aqua green. In general, the elements O, Ca and C were the main elements present, as well as quantities of Si and Fe were very significant in all the cases. The manufacture techniques for the production of pigments and supports coincided with all those reported in literature for the Maya culture; however, influence from the Central Altiplane could be appreciated. The results obtained by XRD show the phases of calcite (CaCO 3 ) and dolomite ferroan (Ca(Mg,Fe)(CO 3 ) 2 ) in all the support. The analyses by FTIR indicated the presence of some agglutinating, but it has not been identified yet. (Author)

  11. Community-Associated Methicillin-Resistant Staphylococcus aureus Case Studies

    Science.gov (United States)

    Sowash, Madeleine G.; Uhlemann, Anne-Catrin

    2014-01-01

    Over the past decade, the emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has changed the landscape of S. aureus infections around the globe. Initially recognized for its ability to cause disease in young and healthy individuals without healthcare exposures as well as for its distinct genotype and phenotype, this original description no longer fully encompasses the diversity of CA-MRSA as it continues to expand its niche. Using four case studies, we highlight a wide range of the clinical presentations and challenges of CA-MRSA. Based on these cases we further explore the globally polygenetic background of CA-MRSA with a special emphasis on generally less characterized populations. PMID:24085688

  12. [Granulomatous lobular mastitis: a clinicopathologic study of 68 cases].

    Science.gov (United States)

    Cheng, Juan; Du, Yu-tang; Ding, Hua-ye

    2010-10-01

    To study the clinical and pathologic features of granulomatous lobular mastitis (GLM). Sixty-eight cases of GLM were retrieved from the archival file. The clinical data and histologic features were retrospectively reviewed. Sixty-eight patients presented with breast mass. Ulceration in overlying breast skin was seen in 9 cases. Most of the patients had history of breast feeding. None of them had evidence of specific infections involving the breast. The clinical and radiologic features mimicked malignancy. Histologically, GLM was characterized by the presence of non-necrotizing granulomas, usually admixed with neutrophils and associated with benign ductolobular units. The ductolobular architecture was still preserved. The duration of follow up ranged from 6 to 36 months. Four patients suffered from disease recurrence. GLM shows clinical and radiologic features reminiscent of breast cancer. Correct diagnosis requires histologic examination of the biopsy specimens.

  13. CARACTERIZACIÓN Y EVALUACIÓN DE AGROECOSISTEMAS A ESCALA PREDIAL. UN ESTUDIO DE CASO: CENTRO AGROPECUARIO PAYSANDÚ (MEDELLÍN, COLOMBIA CHARACTERIZATION AND EVALUATION OF AGROECOSYSTEMS ON A FARM SCALE A STUDY CASE: THE PAYSANDÚ FARMING CENTER.

    Directory of Open Access Journals (Sweden)

    Juan Camilo de los Rios Cardona

    2004-12-01

    Full Text Available Se caracteriza y evalúa el estado, condición y tendencia, de los Agroecosistemas (AE del Centro Agropecuario Paysandú de la Universidad Nacional de Colombia, Sede Medellín, mediante la parametrización y análisis de las variadas Receptividad Tecnológica (RT e Intensidad Tecnológica (IT, con base en la propuesta metodológica de Vélez y Gastó (1979, en cuanto a la diversidad de AE y de usos, manejo y acogida tecnológica, dotación en tecnoestructura e hidroestructura, potencial productivo y servicios a la sociedad local regional y nacional. Los resultados muestran que la mayor parte del área del Centro (72% tiene RT Muy Baja, la cual no admite el establecimiento de Sistemas de Manejo Agrotecnológico (SMA Mecanizados Avanzados. Sin embargo, el 69.8% del área es manejada con SMA adecuados para las restricciones que impone la RT. El 62% del área del Centro, principalmente bajo cobertura de pradera para ganadería de leche, es manejada con SMA avanzado. Como producto de la interacción entre RT y los SMA utilizados, se encontraron seis AE, de los cuales, tres, que representan el 69,8% del área ( 100,2 ha., se manejan con tecnologías adecuadas a sus condiciones biofísicas o de receptividad tecnológica (IT Adecuada, y los otros tres, que representan el 28,57% del área ( 41,3 ha., son manejados con tecnologías que no se corresponden con sus condiciones de RT (IT tradicional, lo que conlleva al deterioro de sus condiciones biofísicas y ecológicas.The state, condition, and tendencies of the agro-ecosystems (AE of the Paysandú Farming Center of the Universidad Nacional de Colombia, Sede Medellín were characterized and evaluated by means of parameterization and analysis of the various Technological Receptivity (RT, after the Spanish initials and Technological Intensity (IT, based upon a methodological proposal of Vélez and Gastó (1999, in terms of AE diversity and of the uses, management, and technological acceptance

  14. Study on multipartite quantum states: preparation, simulation, and characterization

    International Nuclear Information System (INIS)

    Kruszynska, C.

    2009-01-01

    In this thesis different problems are investigated related to the description as well as the manipulation of multipartite quantum states. Because of the superposition principle, the state of a composite quantum system can be entangled, i.e. exhibit quantum correlations between the sites. The entanglement of two-qubit systems is well understood. There is only one kind of entanglement which can be directly related to the value of the Schmidt coefficients. However this is not the case for multipartite entanglement of qubit systems. Unlike in the two-qubit case, a multipartite quantum state can be entangled in many different ways, which complicates the classification and characterization of such states. The storage and manipulation of a quantum state is a challenging task because of the decoherence resulting from the interaction of the state with its environment. One way to overcome this difficulty is to use entanglement purification which will be the subject of the first part of this thesis. Entanglement purification allows to extract a small number of nearly pure states out of a bigger set of mixed states. We review existing bipartite and multipartite entanglement purification protocols and introduce new protocols which are capable of purifying any graph state, enlarging by this the class of states which can be purified. The second part deals with the preparation and distribution of high-fidelity multi-party entangled states via noisy channels and operations. In the particular case of GHZ and cluster states, we study different strategies using bipartite or multipartite purification protocols. The most efficient strategy depends on the target fidelity one wishes to achieve and on the quality of transmission channel and local operations. We show the existence of a crossing point beyond which the strategy making use of the purification of the state as a whole is more efficient than a strategy in which pairs are purified before they are connected to the final state. We

  15. Capturing Cultural Glossaries: Case-study II

    Directory of Open Access Journals (Sweden)

    Matete Madiba

    2011-10-01

    Full Text Available

    ABSTRACT: This case-study attempts to present a brief glossary of Northern Sotho medical terms. It is a follow-up of a similar case-study (Madiba, Mphahlele and Kganyago 2003, which was an attempt to capture and present Northern Sotho cooking terms. Case-study I consists of the names for utensils, ingredients and the processes involved in the preparation of cultural dishes. With both these case-studies, the intention has been to use the opportunities availing themselves for the pres-ervation and valorisation of Northern Sotho, including the extension of its corpora to support national dictionary-making processes. The case-study methodology has been very useful for the purposes of this project and the context within which it was undertaken. It aims to provide a model for the collection and presentation of authentic Northern Sotho terminology which otherwise would hardly have been accessible.

    Keywords: CULTURAL GLOSSARY, INDIGENOUS KNOWLEDGE SYSTEMS, CORPUS, OUTCOMES-BASED EDUCATION, ASSESSMENT CRITERIA, TRADITIONAL MEDICAL TERMS, COMMUNICATIVE APPROACH, STRUCTURAL APPROACH, METONYMY, HANDS-ON ACTIVITIES, TASK-BASED LEARNING

    *****

    OPSOMMING: Die totstandbrenging van kulturele woordversamelings: Ge-vallestudie II. Hierdie gevallestudie probeer om 'n beperkte woordelys van Noord-Sotho- mediese terme aan te bied. Dit is 'n voortsetting van 'n soortgelyke gevallestudie (Madiba, Mpha-hlele en Kganyago 2003 wat 'n poging was om Noord-Sothokookterme te versamel en aan te bied. Gevallestudie I bestaan uit die name van gereedskap, bestanddele, en die prosesse betrokke by die voorbereiding van kulturele geregte. Met altwee hierdie gevallestudies was die bedoeling om die geleenthede te gebruik wat hulleself aanbied vir die bewaring en bestendiging van Noord-Sotho, insluitende die uitbreiding van sy korpora om die nasionale woordeboeksamestellingsprosesse te ondersteun. Die gevallestudiemetodologie was baie nuttig vir die doeleindes van

  16. Physics in Industry: A Case Study

    Science.gov (United States)

    Pratt-Ferguson, Ben

    2007-10-01

    Often ignored and sometimes even considered ``black sheep'' by the university & government-lab physicists, many industrial physicists continue making valuable scientific contributions in diverse areas, from computer science to aero and thermo-dynamics, communications, mathematics, engineering, and simulation, to name a few. This talk will focus on what industrial physicists do, what preparations are beneficial to obtaining a first industrial job, and what the business environment is like for physicists. The case study will be that of the author, starting with undergraduate and graduate studies and continuing on to jobs in industry.

  17. Case studies in atomic collision physics

    CERN Document Server

    McDaniel, Earl Wadsworth

    1972-01-01

    Case Studies in Atomic Collision Physics II focuses on studies on the role of atomic collision processes in astrophysical plasmas, including ionic recombination, electron transport, and position scattering. The book first discusses three-body recombination of positive and negative ions, as well as introduction to ionic recombination, calculation of the recombination coefficient, ions recombining in their parent gas, and three-body recombination at moderate and high gas-densities. The manuscript also takes a look at precision measurements of electron transport coefficients and differential cr

  18. Nanomaterial Case Studies: Nanoscale Titanium Dioxide in ...

    Science.gov (United States)

    EPA announced the availability of the final report, Nanomaterial Case Studies: Nanoscale Titanium Dioxide in Water Treatment and in Topical Sunscreen. This report is a starting point to determine what is known and what needs to be known about selected nanomaterials as part of a process to identify and prioritize research to inform future assessments of the potential ecological and health implications of these materials. Two specific applications of nanoscale titanium dioxide (nano-TiO2) are considered: (1) as an agent for removing arsenic from drinking water; and (2) as an active ingredient in topical sunscreen. These case studies are organized around a comprehensive environmental assessment (CEA) framework that combines a product life cycle perspective with the risk assessment paradigm. They are intended to help identify what may need to be known in order to conduct a comprehensive environmental assessment of the potential risks related to nano-TiO2. These “case studies” do not represent completed or even preliminary assessments, nor are they intended to serve as a basis for risk management decisions in the near term on these specific uses of nano TiO2. Rather, the intent is to use this document in developing the scientific and technical information needed for future assessment efforts.

  19. A Case Study in Corporate Social Responsibility

    Directory of Open Access Journals (Sweden)

    Sharon K. Kendrick

    2014-03-01

    Full Text Available This case study promotes analysis through a brief investigation into the role of corporate social responsibility (CSR in the operation of a multinational corporation as evidenced by Google, Inc. The study focuses on a transnational company in order to observe the impact of CSR practice on a global level. The study will present implications of CSR for corporate management, corporate employees, state regulators, shareholders, and customers in general. In addition, the study will discuss consequences of poor CSR compliance for a multinational corporation. Questions for analysis include implications of CSR, employee retention, development of corporate culture, and evaluation of advantages and disadvantages of different CSR approaches. Upon conclusion of the study, suggestions are made for future collaborative efforts in corporate social responsibility as applied to psychological, sociological, and economical motives. Recruiting and training possibilities also present partnership opportunities for best practice sharing in regards to community, civic, and service engagement.

  20. Terahertz applications in cultural heritage: case studies

    Science.gov (United States)

    Giovannacci, D.; Martos-Levif, D.; Walker, G. C.; Menu, M.; Detalle, V.

    2013-11-01

    Terahertz (THz) spectroscopy and imaging is a non-destructive, non-contact, non-invasive technology emerging as a tool for the analysis of cultural heritage. THz Time Domain Spectroscopy (TDS) techniques have the ability to retrieve information from different layers within a stratified sample, that enable the identification of hidden sub-layers in the case of paints and mural paintings. In this paper, we present the THz TDS2 system developed in the European Commission's 7th Framework Program project CHARISMA [grant agreement no. 228330]. Bespoke single processing algorithms; including a deconvolution algorithm can be deployed to increase the resolution and the global performance of the system. The potential and impact of this work is demonstrated through two case studies of mural paintings, where the capability to reveal the stratigraphy of the artworks is demonstrated.

  1. The case study of biomaterials and biominerals

    Science.gov (United States)

    Del Hoyo Martínez, Carmen

    2013-04-01

    The teaching of biomaterials as case study by on-line platform , susceptible to develop both individually and in groups, got different objectives proposed by the European Higher Education System, among which include: participate actively in the teaching-learning process by students, interpreting situations, adapt processes and solutions. It also improves oral and written communication, analytical skills and synthesis and also the ability to think critically. Biomaterials have their origin in biominerals. These are solid inorganic compounds of defined structure, consisting of molecular control mechanisms that operate in biological systems. Its main functions are: structural support, a reservoir of essential elements, sensors, mechanical protection and storage of toxic elements. Following the demand of materials compatible with certain functional systems of our body, developed biomaterials. Always meet the condition of biocompatibility. Should be tolerated by the body and do not provoke rejection. This involves a comprehensive study of physiological conditions and the anatomy of the body where a biomaterial has to be implemented. The possibility of generating new materials from biominerals has a major impact in medicine and other fields could reach as geology, construction, crystallography, etc. While the study of these issues is in its infancy today, can be viewed as an impact on the art and future technology. Planning case study that students would prepare its report for discussion in subgroups. Occurs then the pooling of individual analysis, joint case discussion and adoption by the subgroup of a consensual solution to the problem. The teacher as facilitator and coordinator of the final case analysis, sharing leads to group-wide class and said the unanimous decision reached by the students and gives his opinion on the resolution of the case. REFERENCES D.P. Ausubel. Psicología Educativa. Un punto de vista cognoscitivo. Trillas. Ed. 1983. E.W. Eisner. Procesos

  2. Using Case Studies to Teach About Global Issues, Bali: A Case Study

    Science.gov (United States)

    Oswald, James M.

    1974-01-01

    The South Pacific island of Bali is used as a case study of overpopulation and food shortage. A brief description of the resources, the typical lifestyle of the Balinese farmer, and possible teaching techniques are given. (DE)

  3. Describing Case Study Method and Identifying the Factors that Contribute to the Successful Conduct of Case Studies

    OpenAIRE

    Ahmad H. Juma'h; Mustafa Cavus

    2001-01-01

    This article has attempted to describe case study, the limitations and critiques on case study methodology and how the proponents have responded to these. Our special focus have been on the debate on theory building from case study research, and a framework for conducting case study research as well as the factors for a successful case study research. The overall conclusion is that the case study has been inappropriately used to generate theories.

  4. An understanding of modified release matrix tablets behavior during drug dissolution as the key for prediction of pharmaceutical product performance - case study of multimodal characterization of quetiapine fumarate tablets.

    Science.gov (United States)

    Kulinowski, Piotr; Woyna-Orlewicz, Krzysztof; Rappen, Gerd-Martin; Haznar-Garbacz, Dorota; Węglarz, Władysław P; Dorożyński, Przemysław P

    2015-04-30

    Motivation for the study was the lack of dedicated and effective research and development (R&D) in vitro methods for oral, generic, modified release formulations. The purpose of the research was to assess multimodal in vitro methodology for further bioequivalence study risk minimization. Principal results of the study are as follows: (i) Pharmaceutically equivalent quetiapine fumarate extended release dosage form of Seroquel XR was developed using a quality by design/design of experiment (QbD/DoE) paradigm. (ii) The developed formulation was then compared with originator using X-ray microtomography, magnetic resonance imaging and texture analysis. Despite similarity in terms of compendial dissolution test, developed and original dosage forms differed in micro/meso structure and consequently in mechanical properties. (iii) These differences were found to be the key factors of failure of biorelevant dissolution test using the stress dissolution apparatus. Major conclusions are as follows: (i) Imaging methods allow to assess internal features of the hydrating extended release matrix and together with the stress dissolution test allow to rationalize the design of generic formulations at the in vitro level. (ii) Technological impact on formulation properties e.g., on pore formation in hydrating matrices cannot be overlooked when designing modified release dosage forms. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Present status and problems of radionuclide studies in emergency cases

    International Nuclear Information System (INIS)

    Ogawa, Kiyoshi

    1983-01-01

    Scintigraphy is just right for diagnosing emergency cases due to its noninvasive and simple method, but emergency radionuclide studies have not become practical as a result of difficulty problems. Recently, nuclear medical devices have become easier to use in operations. It is become of this, that I have submitted this report regarding the problems of radionuclide studies in emergency cases. There were 101 cases (1.4 %) out of 7,310 cases for the year period Sept. 1981 - Aug. 1982. The studies consisted of 12 brain imaging cases, 9 plumonary imaging cases, 22 cardiac study cases (cardio-angiography cases 8, 99m-Tc-PYP myocardium imaging cases 12, 201-Tl myocardium imaging cases 2), 12 renal study cases, 11 G.I. blood loss cases, 35 peripheral angiography cases. In the near future, we will have to be ready to perform emergency radionuclide studies if the need arises. (author)

  6. Oral Narrative Genres as Dialogic Resources for Classroom Literature Study: A Contextualized Case Study of Conversational Narrative Discussion

    Science.gov (United States)

    Juzwik, Mary M.; Nystrand, Martin; Kelly, Sean; Sherry, Michael B.

    2008-01-01

    Five questions guided a case study exploring the relationship between oral narrative and discussion in middle school literature study: (a) Relative to similar classrooms in a large-scale study, how can overall literature instruction be characterized? (b) Relative to similar classrooms in a large-scale study, how well do students achieve in the…

  7. Putting Words in Their Mouth: Writing Dialogue for Case Studies

    Science.gov (United States)

    Herreid, Clyde Freeman

    2018-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This issue discusses dialogue writing guidelines most relevant to case writing.

  8. Deep Attack Weapons Mix Study (DAWMS) Case Study

    National Research Council Canada - National Science Library

    Bexfield, James

    2001-01-01

    .... This report describes the process used to conduct the Deep Attack Weapons Mix Study (DAWMS) in 1995-1997. This case study focuses on the weapons being procured by the Services and whether a joint viewpoint would result in a more effective mix...

  9. Case-Control Studies - An Efficient Observational Study Design

    NARCIS (Netherlands)

    van Stralen, Karlijn J.; Dekker, Friedo W.; Zoccali, Carmine; Jager, Kitty J.

    2010-01-01

    Case-control studies are an efficient research method for investigating risk factors of a disease. The method involves the comparison of the odds of exposure in a patient group with that of the odds of exposure in a control group. As only a minority of the population is included in the study, less

  10. A Case Study Application Of Time Study Model In Paint ...

    African Journals Online (AJOL)

    This paper presents a case study in the development and application of a time study model in a paint manufacturing company. The organization specializes in the production of different grades of paint and paint containers. The paint production activities include; weighing of raw materials, drying of raw materials, dissolving ...

  11. Case studies in organic contaminant hydrogeology

    International Nuclear Information System (INIS)

    Baker, J.A.

    1989-01-01

    The effective management of domestic solid waste and hazardous, toxic, and radioactive waste is a major problem in the area of environmental geology and water sciences throughout the world. A series of case studies is presented of organic contaminants from both solid and hazardous waste disposal facilities to provide examples of these problems. The facilities were investigated to determine risks and liabilities before acquisition, to determine the site hydrogeologic conditions for design of appropriate groundwater monitoring plans, and/or to determine the potential for groundwater contamination. The case studies are of disposal facilities located in glacial tills, carbonaceous weathered clay soils, weathered shale, limestone bedrock, dolomite bedrock, and alluvial and sedimentary deposits. The results of these studies and investigations show certain relationships in the distribution of organic pollutants to the different geologic and hydrogeologic characteristics of each facility. In each of the four case studies, all 129 priority pollutants were analyzed in private wells and/or monitoring wells. The 31 volatile organic compounds (VOCs) of the priority pollutant list were the majority of organic compounds detected. When VOCs are found in groundwater impacted by disposal facilities, they are present in groups and tend to be distributed in patterns based on their relative concentrations. It is rare to find only one or two VOCs from facilities where leakage has been detected. The ethylenes and ethanes appear to be more prevalent and mobile than aromatic VOCs. The aromatics are restricted primarily to leachates and wastes and in monitoring wells located adjacent to facilities. 2 refs., 15 figs

  12. Mathematical modelling a case studies approach

    CERN Document Server

    Illner, Reinhard; McCollum, Samantha; Roode, Thea van

    2004-01-01

    Mathematical modelling is a subject without boundaries. It is the means by which mathematics becomes useful to virtually any subject. Moreover, modelling has been and continues to be a driving force for the development of mathematics itself. This book explains the process of modelling real situations to obtain mathematical problems that can be analyzed, thus solving the original problem. The presentation is in the form of case studies, which are developed much as they would be in true applications. In many cases, an initial model is created, then modified along the way. Some cases are familiar, such as the evaluation of an annuity. Others are unique, such as the fascinating situation in which an engineer, armed only with a slide rule, had 24 hours to compute whether a valve would hold when a temporary rock plug was removed from a water tunnel. Each chapter ends with a set of exercises and some suggestions for class projects. Some projects are extensive, as with the explorations of the predator-prey model; oth...

  13. Prayer Healing: A Case Study Research Protocol.

    Science.gov (United States)

    Kruijthoff, Dirk J; van der Kooi, Cornelis; Glas, Gerrit; Abma, Tineke A

    2017-01-01

    Context • Prayer healing is a common practice in many religious communities around the world. Even in the highly secularized Dutch society, cases of prayer healing are occasionally reported in the media, often generating public attention. There is an ongoing debate regarding whether such miraculous cures do actually occur and how to interpret them. Objective • The aim of the article was to present a research protocol for the investigation of reported cases of remarkable and/or unexplained healing after prayer. Design • The research team developed a method to perform a retrospective, case-based study of prayer healing. Reported prayer healings can be investigated systematically in accordance with a step-by-step methodology. The focus is on understanding the healing by studying it from multiple perspectives, using both medical judgment and patients' narratives collected by qualitative methods Setting • The study occurred at Vrije Universiteit (VU) and VU Medical Center (Amsterdam, Netherlands) as well as the general medical practice of the first author. Participants • Potential participants could be any individuals in the Netherlands or neighboring countries who claim to have been healed through prayer. The reports of healing came from multiple sources, including the research team's medical practices and their direct vicinities, newspaper articles, prayer healers, and medical colleagues. Outcome Measures • Medical data were obtained before and after prayer. Subsequently, a member of a research team and of a medical assessment committee made a standardized judgment that evaluated whether a cure was clinically remarkable or scientifically unexplained. The participants' experiences and insider perspectives were studied, using in-depth interviews in accordance with a qualitative research methodology, to gain insight into the perceptions and explanations of the cures that were offered by participants and by the members of the medical assessment committee. The

  14. Global Profiling and Novel Structure Discovery Using Multiple Neutral Loss/Precursor Ion Scanning Combined with Substructure Recognition and Statistical Analysis (MNPSS): Characterization of Terpene-Conjugated Curcuminoids in Curcuma longa as a Case Study.

    Science.gov (United States)

    Qiao, Xue; Lin, Xiong-hao; Ji, Shuai; Zhang, Zheng-xiang; Bo, Tao; Guo, De-an; Ye, Min

    2016-01-05

    To fully understand the chemical diversity of an herbal medicine is challenging. In this work, we describe a new approach to globally profile and discover novel compounds from an herbal extract using multiple neutral loss/precursor ion scanning combined with substructure recognition and statistical analysis. Turmeric (the rhizomes of Curcuma longa L.) was used as an example. This approach consists of three steps: (i) multiple neutral loss/precursor ion scanning to obtain substructure information; (ii) targeted identification of new compounds by extracted ion current and substructure recognition; and (iii) untargeted identification using total ion current and multivariate statistical analysis to discover novel structures. Using this approach, 846 terpecurcumins (terpene-conjugated curcuminoids) were discovered from turmeric, including a number of potentially novel compounds. Furthermore, two unprecedented compounds (terpecurcumins X and Y) were purified, and their structures were identified by NMR spectroscopy. This study extended the application of mass spectrometry to global profiling of natural products in herbal medicines and could help chemists to rapidly discover novel compounds from a complex matrix.

  15. Wind to Hydrogen in California: Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Antonia, O.; Saur, G.

    2012-08-01

    This analysis presents a case study in California for a large scale, standalone wind electrolysis site. This is a techno-economic analysis of the 40,000 kg/day renewable production of hydrogen and subsequent delivery by truck to a fueling station in the Los Angeles area. This quantity of hydrogen represents about 1% vehicle market penetration for a city such as Los Angeles (assuming 0.62 kg/day/vehicle and 0.69 vehicles/person) [8]. A wind site near the Mojave Desert was selected for proximity to the LA area where hydrogen refueling stations are already built.

  16. Case study: Bioremediation in the Aleutian Islands

    International Nuclear Information System (INIS)

    Steward, K.J.; Laford, H.D.

    1995-01-01

    This case study describes the design, construction, and operation of a bioremediation pile on Adak Island, which is located in the Aleutian Island chain. Approximately 1,900 m 3 of petroleum-contaminated soil were placed in the bioremediation pile. The natural bioremediation process was enhanced by an oxygen and nutrient addition system to stimulate microbial activity. Despite the harsh weather on the island, after the first 6 months of operation, laboratory analyses of soil samples indicated a significant (80%) reduction in diesel concentrations

  17. Reinforcement learning: Solving two case studies

    Science.gov (United States)

    Duarte, Ana Filipa; Silva, Pedro; dos Santos, Cristina Peixoto

    2012-09-01

    Reinforcement Learning algorithms offer interesting features for the control of autonomous systems, such as the ability to learn from direct interaction with the environment, and the use of a simple reward signalas opposed to the input-outputs pairsused in classic supervised learning. The reward signal indicates the success of failure of the actions executed by the agent in the environment. In this work, are described RL algorithmsapplied to two case studies: the Crawler robot and the widely known inverted pendulum. We explore RL capabilities to autonomously learn a basic locomotion pattern in the Crawler, andapproach the balancing problem of biped locomotion using the inverted pendulum.

  18. Case study of nuclear power planning

    International Nuclear Information System (INIS)

    Covarrubias, A.J.; Lane, J.A.

    1976-01-01

    An improved version of the computer programme WASP (Wien Automatic System Planning) is described by the example of a case study. The aim of an optimal power plant development within the economic development is reached over several steps the most important parameters of which are explained in detail. To use the method it is necessary to know and to describe the energy and electricity supply situation of the country referred to. The programme development described has proved to be good in use in an international frame. The IAEA offers its help to all prospected customers in their initial period with the programme WASP. (UA) [de

  19. Makerspaces in Engineering Education: A Case Study

    DEFF Research Database (Denmark)

    Jensen, Lasse Skovgaard; Özkil, Ali Gürcan; Mougaard, Krestine

    2016-01-01

    it by opening makerspaces and adopting elements of the Maker Movement in their offerings. This paper investigates how university driven makerspaces can affect engineering design and product development education trough a case study. We provide our findings based on interviews and data collected from educators......, students the administrative and workshop staff of the makerspace. The findings are used to outline the challenges in incorporating the offerings of makerspaces. By discussing these challenges we identify opportunities for turning university makerspaces into innovation hubs and platforms that can support...

  20. Russian Media Educators: Case Studies Portraits

    Directory of Open Access Journals (Sweden)

    Alexander Fedorov

    2013-01-01

    Full Text Available This article is devoted to case studies of the media education works of some well knowns Russian media educators. The analysis of media educational work of the famous Russian media educators leads us to the conclusion that media education in Russia is developing, building on the synthesis of the aesthetic, socio-cultural, and practical concepts, with a focus on the development of media competence of the audience, mainly school and youth. The enthusiasts of media education, even devoid of substantial public support for its innovative projects, achieve significant and meaningful results.

  1. Metrology in Pharmaceutical Industry - A Case Study

    International Nuclear Information System (INIS)

    Yuvamoto, Priscila D.; Fermam, Ricardo K. S.; Nascimento, Elizabeth S.

    2016-01-01

    Metrology is recognized by improving production process, increasing the productivity, giving more reliability to the measurements and consequently, it impacts in the economy of a country. Pharmaceutical area developed GMP (Good Manufacture Practice) requeriments, with no introduction of metrological concepts. However, due to Nanomedicines, it is expected this approach and the consequent positive results. The aim of this work is to verify the level of metrology implementation in a Brazilian pharmaceutical industry, using a case study. The purpose is a better mutual comprehension by both areas, acting together and governmental support to robustness of Brazilian pharmaceutical area. (paper)

  2. Myonecrosis in Sickle Cell Anemia: Case Study.

    Science.gov (United States)

    Turaga, Lalita Prabha; Boddu, Prajwal; Kipferl, Steve; Basu, Anupam; Yorath, Martin

    2017-01-30

    BACKGROUND Myonecrosis is one of the more poorly studied, painful manifestations of sickle cell crisis. Medical literature is sparse detailing the manifestations and management of such symptoms. In myonecrosis, red cells containing sickle hemoglobin become rigid, resulting in reduced blood flow and myonecrosis. CASE REPORT We present a case study of a patient in sickle cell crisis with an episode of acute pain and swelling to the intrinsic muscles of the foot as a prominent feature of the crises. Although muscle biopsy is considered the gold standard for the diagnosis of myositis or myonecrosis, a low intensity signal on T1 and high intensity signal on T2 at the affected muscle belly can be as conclusive as imaging studies. In an actively sickling patient any invasive intervention should be avoided as it can result in ischemic necrosis of the tissues, due to interruption of capillary flow in end-arteries. CONCLUSIONS Early recognition is critical in sickle cell disease management, allowing for prompt and aggressive fluid resuscitation which remains a cornerstone in the management of most sickle cell vaso-occlusive crises. In this instance, off loading the extremity and early fluid resuscitation resolved the pain and swelling and prevented myonecrosis.

  3. Case Study: Puttin' on the Ritz: How to Put Science into Cases

    Science.gov (United States)

    Herreid, Clyde Freeman

    2017-01-01

    There are multiple ways to put science into a case. This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue discusses different ways of presenting science in case studies.

  4. Collagenous sprue: a clinicopathologic study of 12 cases.

    LENUS (Irish Health Repository)

    Maguire, Aoife A

    2012-02-01

    Collagenous sprue is a rare form of small bowel enteropathy characterized by chronic diarrhea and progressive malabsorption with little data available on its natural history. The pathologic lesion consists of subepithelial collagen deposition associated with variable alterations in villous architecture. The small bowel biopsies of 12 cases were reviewed. Clinical details, celiac serology, and T-cell receptor gene rearrangement study results, when available, were collated. There were 8 females and 4 males (age ranged from 41 to 84 y) who presented with chronic diarrhea and weight loss. Small intestinal biopsies showed subepithelial collagen deposition with varying degrees of villous atrophy and varying numbers of intraepithelial lymphocytes. Four patients had previous biopsies showing enteropathic changes without collagen deposition. Seven cases were associated with collagenous colitis and 1 also had features of lymphocytic colitis. Three patients also had collagen deposition in gastric biopsies. One case was associated with lymphocytic gastritis. Celiac disease (CD, gluten-sensitive enteropathy) was documented in 4 patients. Five patients made a clinical improvement with combinations of a gluten-free diet and immunosuppressive therapy. Two patients died of complications of malnutrition and 1 of another illness. Clonal T-cell populations were identified in 5 of 6 cases tested. Four of these patients improved clinically after treatment but 1 has died. Collagenous sprue evolved on a background of CD in 4 cases. There was no history of CD in others and these cases may be the result of a biologic insult other than gluten sensitivity. None has developed clinical evidence of lymphoma to date.

  5. Flow cytometric characterization of phenotype, DNA indices and p53 gene expression in 55 cases of acute leukemia.

    Science.gov (United States)

    Powari, Manish; Varma, Neelam; Varma, Subhash; Marwaha, Ram Kumar; Sandhu, Harpreet; Ganguly, Nirmal Kumar

    2002-06-01

    To characterize the phenotype of acute leukemia cases using flow cytometry, to detect mixed lineage cases and to use DNA index determination, including S-phase fraction (SPF) and p53 detection, to find if there was any correlation of SPF and p53 expression with outcome. Fifty-five cases of acute leukemia were enrolled in this study. A complete hemogram and routine bone marrow examination, including cytochemistry, was done. Mycloperoxidase-negative cases were evaluated on a flow cytometer using monoclonal antibodies. DNA indices were determined by flow cytometry in all cases, and p53 was detected immunohistochemically using the alkaline phosphatase/antialkaline phosphatase technique. Acute myeloblastic leukemia (AML) was diagnosed in 32 cases; acute lymphoblastic leukemia (ALL) was diagnosed in 18 (14 B lineage and 4 T line age). Four cases showed mixed lineage leukemia, and undifferentiated acute leukemia was diagnosed in one case. The mean/range of SPF for these groups were 3.76/0.33-6.91, 6.25/0.15-21.4, 2.89/0.35-10.64, 2.60/0.72-6.94 and 7.34, respectively. Aneuploidy was detected in two cases of B-lineage ALL and tetraploidy in a case of AML-M7, while all others were diploid p53. Was detected in 6 of 55 cases (10.90%). Follow-up was available for 24 patients. Five patients relapsed, and four had B-cell type ALL and were diploid and expressed no p53 gene. SPF% did not show any correlation with outcome. These data suggest that within acute leukemia subtypes, there is a wide variation in SPF. SPF does not seem to correlate with outcome. Immunophenotyping is essential to determine the lineage in myeloperoxidase-negative cases. It is perhaps the only way to diagnose mixed lineage leukemia and aberrant expression of markers presently. The p53 gene was detected less frequently. However, more studies are required from different centers with longer follow-up to evaluate prognostic significance.

  6. A postural `stressed` cerebral HMPAO case study

    Energy Technology Data Exchange (ETDEWEB)

    Williams, R.C.; Jost, G.M.; Bolitho, L.; Grantham, M. [Wangaratta District Hospital, VIC (Australia)

    1998-03-01

    Full text: This case study represents an example of the utility of postural hypoperfusion stressed HMPAO SPECT. An elderly woman of 78 with a long history of giddiness was referred to our laboratory for examination of possible cerebral ischaemia. She had recurrent dizzy episodes, sometimes posture related, over the past few years and had suffered several falls. Cerebral DSA revealed minimal disease. CT scans were reported as normal. Carotid duplex Doppler studies revealed bilateral plaque disease in the carotid bulbs extending to the origins of the ICAs which were not significant stenoses. Postural symptoms were induced by standing the patient up rapidly and HMPAO was administered at the same time. A SPECT scan of the brain was performed. Quantitative analysis showed a left to right decrease of 10.8% in the temporo-occipital area, 5.6% in the temporo-parietal area and 2.5% in the cerebellar and parietal areas. Images revealed moderately reduced tracer concentration in the left half of the cerebellum and the left occipital region extending as far forward as the temporo-parietal region A repeat HMPAO SPECT scan without stress was normal. This would appear to indicate reversible ischaemia in the left posterior region, and is consistent with the reported symptoms. This case illustrates the usefulness of HMPAO in the diagnosis of reversible cerebral ischaemia.

  7. Sacroiliac joint dysfunction: a case study.

    Science.gov (United States)

    Murray, William

    2011-01-01

    Pain is a widespread issue in the United States. Nine of 10 Americans regularly suffer from pain, and nearly every person will experience low back pain at one point in their lives. Undertreated or unrelieved pain costs more than $60 billion a year from decreased productivity, lost income, and medical expenses. The ability to diagnose and provide appropriate medical treatment is imperative. This case study examines a 23-year-old Active Duty woman who is preparing to be involuntarily released from military duty for an easily correctable medical condition. She has complained of chronic low back pain that radiates into her hip and down her leg since experiencing a work-related injury. She has been seen by numerous providers for the previous 11 months before being referred to the chronic pain clinic. Upon the first appointment to the chronic pain clinic, she has been diagnosed with sacroiliac joint dysfunction. This case study will demonstrate the importance of a quality lower back pain assessment.

  8. Delivering Online Examinations: A Case Study

    Directory of Open Access Journals (Sweden)

    John MESSING

    2004-07-01

    Full Text Available Delivering Online Examinations: A Case Study Jason HOWARTH John MESSING Irfan ALTAS Charles Sturt University Wagga Wagga-AUSTRALIA ABSTRACT This paper represents a brief case study of delivering online examinations to a worldwide audience. These examinations are delivered in partnership with a commercial online testing company as part of the Industry Master’s degree at Charles Sturt University (CSU. The Industry Master’s degree is an academic program for students currently employed in the IT industry. Using Internet Based Testing (IBT, these students are examined in test centres throughout the world. This offers many benefits. For example, students have the freedom of sitting exams at any time during a designated interval. Computer-based testing also provides instructors with valuable feedback through test statistics and student comments. In this paper, we document CSU’s use of the IBT system, including how tests are built and delivered, and how both human and statistical feedback is used to evaluate and enhance the testing process.

  9. Organisational culture and learning: a case study.

    Science.gov (United States)

    Bell, Elaine

    2013-11-01

    To explore the impact organisational cultures have on the learning experience of student nurses and identify the influencing factors. A case study approach was used. The single case being a Defence School of Health Care Studies (DSHCS) and the multiple units of analysis: student nurses, the lecturers and Student Standing Orders. An in depth three dimensional picture was achieved using multiple data collection methods: interview, survey, observation and document analysis. The findings suggest that the DSHCS is perceived to be a sub-culture within a dominant civilian learning culture. Generally, the students and staff believed that the DSHCS is an excellent learning environment and that the defence students overall are high achievers. The common themes that appeared from the data were image, ethos, environment, discipline, support, welfare and a civilian versus military way of thinking. The learning experience of defence student nurses is very positive and enhanced by the positive learning culture of the civilian Higher Educational Institution. The factors influencing a positive learning experience that can be impacted by the overarching culture are discipline, image, ethos of adult learning, support and welfare. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. A postural 'stressed' cerebral HMPAO case study

    International Nuclear Information System (INIS)

    Williams, R.C.; Jost, G.M.; Bolitho, L.; Grantham, M.

    1998-01-01

    Full text: This case study represents an example of the utility of postural hypoperfusion stressed HMPAO SPECT. An elderly woman of 78 with a long history of giddiness was referred to our laboratory for examination of possible cerebral ischaemia. She had recurrent dizzy episodes, sometimes posture related, over the past few years and had suffered several falls. Cerebral DSA revealed minimal disease. CT scans were reported as normal. Carotid duplex Doppler studies revealed bilateral plaque disease in the carotid bulbs extending to the origins of the ICAs which were not significant stenoses. Postural symptoms were induced by standing the patient up rapidly and HMPAO was administered at the same time. A SPECT scan of the brain was performed. Quantitative analysis showed a left to right decrease of 10.8% in the temporo-occipital area, 5.6% in the temporo-parietal area and 2.5% in the cerebellar and parietal areas. Images revealed moderately reduced tracer concentration in the left half of the cerebellum and the left occipital region extending as far forward as the temporo-parietal region A repeat HMPAO SPECT scan without stress was normal. This would appear to indicate reversible ischaemia in the left posterior region, and is consistent with the reported symptoms. This case illustrates the usefulness of HMPAO in the diagnosis of reversible cerebral ischaemia

  11. Scheduling job shop - A case study

    Science.gov (United States)

    Abas, M.; Abbas, A.; Khan, W. A.

    2016-08-01

    The scheduling in job shop is important for efficient utilization of machines in the manufacturing industry. There are number of algorithms available for scheduling of jobs which depend on machines tools, indirect consumables and jobs which are to be processed. In this paper a case study is presented for scheduling of jobs when parts are treated on available machines. Through time and motion study setup time and operation time are measured as total processing time for variety of products having different manufacturing processes. Based on due dates different level of priority are assigned to the jobs and the jobs are scheduled on the basis of priority. In view of the measured processing time, the times for processing of some new jobs are estimated and for efficient utilization of the machines available an algorithm is proposed and validated.

  12. Location of existing Case Studies on Open Education

    OpenAIRE

    Burke, Siobhan

    2014-01-01

    Members of the Open Education Special Interest Group have collected a selection of short case studies on Open Education. View all of the case studies at http://repository.alt.ac.uk/view/divisions/CaseStudies/ Location of existing Case Studies on Open Education: The following lists aims to capture and amalgamate the various different case study sources which have been created and developed within the UK around experiences of Open Educational Resources.

  13. Violence against Women and Gastroschisis: A Case-Control Study

    Directory of Open Access Journals (Sweden)

    Daniel Ruiz

    2013-10-01

    Full Text Available Background: Gastroschisis, a birth defect characterized by herniated fetal abdominal wall, occurs more commonly in infants born to teenage and young mothers. Ischemia of the vascular vitelline vessels is the likely mechanism of pathogenesis. Given that chronic stress and violence against women are risk factors for cardiovascular disease we explored whether these may represent risk factors for gastroschisis, when they occur during pregnancy. A case-control study was conducted, with 15 incident cases of children born with gastroschisis in the Region of Murcia, Spain, from December 2007 to June 2013. Forty concurrent controls were recruited at gestation weeks 20–24 or post-partum. All mothers of cases and controls completed a comprehensive, in-person, ‘green sheet’ questionnaire on environmental exposures. Results: Mothers of children with gastroschisis were younger, smoked more cigarettes per week relative to controls, were exposed to higher amounts of illegal drugs, and suffered from domestic violence more frequently than the controls. Multivariable logistic regression analysis highlights periconceptional ‘gender-related violence’ (OR: 16.6, 95% CI 2.7 to 101.7 and younger maternal age (OR 1.1, 95% CI 1.0–1.3. Conclusions: Violence against pregnant women is associated with birth defects, and should be studied in more depth as a cause-effect teratogenic. Psychosocial risk factors, including gender-based violence, are important for insuring the health and safety of the pregnant mother and the fetus.

  14. The Effect of Using Case Studies in Business Statistics

    Science.gov (United States)

    Pariseau, Susan E.; Kezim, Boualem

    2007-01-01

    The authors evaluated the effect on learning of using case studies in business statistics courses. The authors divided students into 3 groups: a control group, a group that completed 1 case study, and a group that completed 3 case studies. Results evidenced that, on average, students whom the authors required to complete a case analysis received…

  15. On misunderstandings in connection with case-studies

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    2005-01-01

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...

  16. Stakeholders and Apart Hotels: Multiple Case Study

    Directory of Open Access Journals (Sweden)

    Elizabeth Kyoko Wada

    2012-09-01

    Full Text Available Means of accommodation involve a wide range of social actors and agents, as well as different business models. Management strategies in this sector have been increasingly important for long-term sustainability and competitiveness of business organizations. This study aims to analyze the interactions between apart-hotels and their stakeholders to foster an improvement of services provided, aligning the interface of strategic management from the point of view of managers and their key stakeholders. It is an exploratory study, with qualitative chacter, along with multiple case studies of the following establishments: Travel Inn, Hotels Slaviero and Etoile george v. Brazilian enterprises, which manage lodging facilities with apart-hotel concepts, combining features that enable comparative analysis of the study. For conceptual understanding, this study was based on literature about stakeholders, taking the work of Freeman (1984 and Freeman et al (2010 as main references. The research was conducted through semi-structured interviews with managers of lodging facilities and their key stakeholders and through direct observation and documentation. We found that not all groups of influence are considered in the planning of service flats. However, the organizations surveyed indicated that the market has realized the importance of the groups that exert influence and are influenced by their goals, and are therefore increasingly alert for integration of such groups in their strategic planning.

  17. Embodiment of the Spirit: A Case Study

    Directory of Open Access Journals (Sweden)

    Jan Grimell

    2017-02-01

    Full Text Available Adopting a longitudinal approach to exploring the psychology of the transition from military to civilian life, one case study is presented that adds a spiritual perspective to the transition process. This case study serves as an example representative from a group of participants who have been followed through a research project on identity reconstruction during the transition to civilian life. This individual, not unlike many others within the group, undergoes an unexpected progression of the military I-position of the self throughout the process of becoming a civilian. This study utilizes a dialogical approach to the identity work to further the understanding of longitudinal adjustments to the self. An analysis of the narrative developments and interactions among pre-existing and new I-positions of the self over time has been made based upon three annually conducted interviews spanning from 2014 to 2016. The results lead to the suggestion that if a military I-position of the self grows more salient and voiced throughout the process of transitioning into civilian life, then this vocalization may be related to the spirit of a person embodied in a specific I-position of the self. Such growth of a military I-position after leaving active service may gravitate around a deep sense of “who I am” with a profound sense of meaning attached to this position. Instead of perceiving as an unwanted development the growth of a military sense of “who I am,” one should acknowledge it as a deeper dimension of self and life. It is important to find an outlet for such a progression of the self so as to sustain balance and dialogue. Future research is encouraged to further examine these qualitative findings.

  18. Quality improvement initiatives in a case management service: case study.

    Science.gov (United States)

    Davies, Deborah J

    2015-01-01

    This article explores the importance of quality practices in underpinning the person-centred approach at a Community Options Program (COP) case management service in northern NSW. The NSW community care sector does not have a statutory excellence body to identify, promote and support improved practices and quality and safety across community services, and therefore the COP provider decided to establish a dedicated role to focus on the quality improvement of its service. The subsequent quality improvement initiatives have included mapping the clients' journey through the service, identifying areas to standardise practice, and creating service pathways. The clients' journey was used as the framework to identify where standardised practice was required, and a robust process was implemented to develop over 25 good practice guidelines and tools that addressed the variations in practice and enabled the service pathways to be developed. Prior to trialling the guidelines and tools, staff received education sessions on the anticipated changes to practice, and the practicality and applicability of the guidelines were evaluated at the end of the trials. This information was reviewed and the guidelines were amended accordingly before being rolled out. The guidelines have been in use for over 12 months and have provided the benchmark against which to audit practice, and have resulted in key performance improvements such as an increase in client review rates and a rise in the feedback response rate from clients, with a noticeable shift in the comments about the brokered support worker to acknowledging the role of their case manager. Formalising informal supports for those clients that lived alone also increased, which means these people are less reliant on services and there is a reduced risk of social isolation.

  19. Antenna coupling study for ICWC plasma characterization in TEXTOR

    Indian Academy of Sciences (India)

    2015-11-27

    Home; Journals; Pramana – Journal of Physics; Volume 80; Issue 1. Antenna coupling study for ICWC plasma characterization in ... Proceedings of the International Workshop/Conference on Computational Condensed Matter Physics and Materials Science (IWCCMP-2015). Posted on November 27, 2015. Guest Editors: ...

  20. Logistics opportunity costs: A mining case study

    Directory of Open Access Journals (Sweden)

    Leani van Jaarsveld

    2013-11-01

    Full Text Available This study highlighted the importance of determining the impact that an ineffective mode of transport has on a firm’s transportation model and costs. The main focus of this study was to determine the logistics opportunity costs of using road transport within a mining firm. A case study approach was followed, as the investigation aimed to analyse a complex problem experienced by one company and present it in an easily understandable format. From the results of this study, it was apparent that the logistics opportunity costs associated with the mode of transport was substantial. This highlighted the need for firms to revise their choice of transport mode on a regular basis, as it has a major impact not only on their transportation costs, but also on their inventory holding and carbon emissions. The results also have implications for South Africa’s only freight railway, Transnet Freight Rail, which should not only focus on expanding its existing capacity, but also on improving its customer service delivery whilst containing tariff increases.

  1. Dosimetric characterization of two radium sources for retrospective dosimetry studies

    Energy Technology Data Exchange (ETDEWEB)

    Candela-Juan, C., E-mail: ccanjuan@gmail.com [Radiation Oncology Department, La Fe University and Polytechnic Hospital, Valencia 46026, Spain and Department of Atomic, Molecular and Nuclear Physics, University of Valencia, Burjassot 46100 (Spain); Karlsson, M. [Division of Radiological Sciences, Department of Medical and Health Sciences, Linköping University, Linköping SE 581 85 (Sweden); Lundell, M. [Department of Medical Physics and Oncology, Karolinska University Hospital and Karolinska Institute, Stockholm SE 171 76 (Sweden); Ballester, F. [Department of Atomic, Molecular and Nuclear Physics, University of Valencia, Burjassot 46100 (Spain); Tedgren, Å. Carlsson [Division of Radiological Sciences, Department of Medical and Health Sciences, Linköping University, Linköping SE 581 85, Sweden and Swedish Radiation Safety Authority, Stockholm SE 171 16 (Sweden)

    2015-05-15

    Purpose: During the first part of the 20th century, {sup 226}Ra was the most used radionuclide for brachytherapy. Retrospective accurate dosimetry, coupled with patient follow up, is important for advancing knowledge on long-term radiation effects. The purpose of this work was to dosimetrically characterize two {sup 226}Ra sources, commonly used in Sweden during the first half of the 20th century, for retrospective dose–effect studies. Methods: An 8 mg {sup 226}Ra tube and a 10 mg {sup 226}Ra needle, used at Radiumhemmet (Karolinska University Hospital, Stockholm, Sweden), from 1925 to the 1960s, were modeled in two independent Monte Carlo (MC) radiation transport codes: GEANT4 and MCNP5. Absorbed dose and collision kerma around the two sources were obtained, from which the TG-43 parameters were derived for the secular equilibrium state. Furthermore, results from this dosimetric formalism were compared with results from a MC simulation with a superficial mould constituted by five needles inside a glass casing, placed over a water phantom, trying to mimic a typical clinical setup. Calculated absorbed doses using the TG-43 formalism were also compared with previously reported measurements and calculations based on the Sievert integral. Finally, the dose rate at large distances from a {sup 226}Ra point-like-source placed in the center of 1 m radius water sphere was calculated with GEANT4. Results: TG-43 parameters [including g{sub L}(r), F(r, θ), Λ, and s{sub K}] have been uploaded in spreadsheets as additional material, and the fitting parameters of a mathematical curve that provides the dose rate between 10 and 60 cm from the source have been provided. Results from TG-43 formalism are consistent within the treatment volume with those of a MC simulation of a typical clinical scenario. Comparisons with reported measurements made with thermoluminescent dosimeters show differences up to 13% along the transverse axis of the radium needle. It has been estimated that

  2. Subungual squamous cell carcinoma: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Neill, Cory J., E-mail: coryjneill@gmail.com

    2017-07-01

    The purpose of this case study is to describe a dosimetric delivery of radiation to a superficial disease process involving the skin and bone of the distal finger. A 76-year-old male patient presented with a subungual squamous cell carcinoma (SCC) of the left distal index finger with bony involvement. The patient refused conventional surgical treatment but agreed to external beam radiation therapy (EBRT). There is a gap in the current literature describing how to successfully immobilize fingers and which EBRT modality is dosimetrically advantageous in treating them. The construction of a simple immobilization method with the patient in a reproducible position is described. The use of photons and electrons were compared ultimately showing photons to be dosimetrically advantageous. Long-term efficacy of the treatment was not evaluated because of patient noncompliance.

  3. Case studies of attacks on communication networks

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Sin Bok; Han, Eon Suk [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1996-06-15

    Recently, as the computer hardware and communications are developed, the data exchange through inter-networking has been highlighted and the data is being recognized as a great asset. Most of the organizations, businesses and enterprises are open to the external world-computer communication networks, attention must be focused on the securities of the information infrastructure. A government organization has been developing 'Circuits Analyzers', and 'Hacker-Tracking Program' and is struggling to track down sneakers. In this report, we analyze the contents of the cases where the communication network has been invaded, from the past up until now in Korea. This report also contains the result of a study on E-mail security, for the protection of KAERI Integrated Management Information System under which utilizes the CALS concepts and web services. (Author)

  4. Understanding Support - lessons from a case study

    Directory of Open Access Journals (Sweden)

    Chris Sauer

    1993-11-01

    Full Text Available Support from top management and others is agreed to be an important factor in information systems success and failure, but little is written about how it has its effect and how it might be managed to a project's advantage. A recently developed conceptual framework is described. It covers the nature and forms of support, the way support affects project outcomes, the bases on which support is provided, and the strategies by which support may be managed. The framework is used to analyse a case study in several stages. At the end of the analysis of each stage, the framework's utility is assessed in terms of its explanatory value and the practical advice it suggests. Areas for further research are identified.

  5. Environmental Comparative Risk Assessment: A Case Study

    International Nuclear Information System (INIS)

    Ali, M.M.

    2007-01-01

    Health and environmental impacts associated with energy production and industrial activities as well as food production and agricultural activities have had great concern in the last decades. Early activities emerged in late 80s of the last century through an Inter- Agency project (lAEA, UNDY, WHO, ... ) on the comparative risk assessment from energy systems and industrial complexes. A work-shop on Risk Assessment and Management in large industrial areas was held in Alexandria Egypt on 20-33 Det 1993, sponsored by IAEA. Several conferences, experts work groups and workshops were held there of Recent trends in determining risks are: 1. Use of probabilistic risk assessment approach to identify hazardous activities and accident scenario. 2. development of data base on failure probabilities and appropriate physical models. 3. Development of related directives and regulations and criteria Comparative risk assessment case study as a tool for comparing risk is emphasized Criteria of exposure to human and ecological risks are addressed

  6. Case studies of attacks on communication networks

    International Nuclear Information System (INIS)

    Kang, Sin Bok; Han, Eon Suk

    1996-06-01

    Recently, as the computer hardware and communications are developed, the data exchange through inter-networking has been highlighted and the data is being recognized as a great asset. Most of the organizations, businesses and enterprises are open to the external world-computer communication networks, attention must be focused on the securities of the information infrastructure. A government organization has been developing 'Circuits Analyzers', and 'Hacker-Tracking Program' and is struggling to track down sneakers. In this report, we analyze the contents of the cases where the communication network has been invaded, from the past up until now in Korea. This report also contains the result of a study on E-mail security, for the protection of KAERI Integrated Management Information System under which utilizes the CALS concepts and web services. (Author)

  7. Anxiety or neurosis: case report study

    Directory of Open Access Journals (Sweden)

    Miloš Židanik

    2005-11-01

    Full Text Available Background: With the publication of the Diagnostic and Statistical Manual, Third Edition (DSM-III in 1980, anxiety disorder was first identified as a diagnostic entity. A new theoretical approach regarding aetiology of anxiety disorders came next into the view, far from Freud’s psychoanalytical pathways. The consequences were new therapeutic guidelines, including psychopharmacotherapy and the use of behavioural and cognitive psychotherapy.Methods: The paper presents a case report study of a patient with social phobia. The use of analytical oriented psychotherapy, which helped to resolve Axis I symptoms, is described.Conclusions: In spite of new therapeutic guidelines there is still a certain population of patients with the need for psychoanalytical oriented psychotherapy. If we are to surrender the Freud’s legacy to the medical history, we will weaken psychiatry as a science and will narrow our therapeutic field.

  8. LM2500+ Brush Seal Case Study

    Science.gov (United States)

    Haaser, Fred G.

    2006-01-01

    The LM2500+ industrial aeroderivative gas turbine, a 25% enhanced power derivative of the LM2500 gas turbine, recently completed its development test program during the period 5/96 - 10/96. Early in the engine program a Quality Function Deployment (QFD) process was used to determine customer needs for this project.The feedback obtained from the QFD process showed without doubt that gas turbine customers now emphasize product reliability and availability at the top of their needs. One area of development on the LM2500+ was to investigate the use of a brush seal as a means to reduce undesirable turbine cooling leakages within the turbine mid frame in order to enhance part life. This presentation presents a case study on the factors that went into evaluating a brush seal during engine test, test results, and the ultimate decision not to implement the brush seal for cost and other reasons.

  9. A case study in pathway knowledgebase verification

    Directory of Open Access Journals (Sweden)

    Shah Nigam H

    2006-04-01

    Full Text Available Abstract Background Biological databases and pathway knowledgebases are proliferating rapidly. We are developing software tools for computer-aided hypothesis design and evaluation, and we would like our tools to take advantage of the information stored in these repositories. But before we can reliably use a pathway knowledgebase as a data source, we need to proofread it to ensure that it can fully support computer-aided information integration and inference. Results We design a series of logical tests to detect potential problems we might encounter using a particular knowledgebase, the Reactome database, with a particular computer-aided hypothesis evaluation tool, HyBrow. We develop an explicit formal language from the language implicit in the Reactome data format and specify a logic to evaluate models expressed using this language. We use the formalism of finite model theory in this work. We then use this logic to formulate tests for desirable properties (such as completeness, consistency, and well-formedness for pathways stored in Reactome. We apply these tests to the publicly available Reactome releases (releases 10 through 14 and compare the results, which highlight Reactome's steady improvement in terms of decreasing inconsistencies. We also investigate and discuss Reactome's potential for supporting computer-aided inference tools. Conclusion The case study described in this work demonstrates that it is possible to use our model theory based approach to identify problems one might encounter using a knowledgebase to support hypothesis evaluation tools. The methodology we use is general and is in no way restricted to the specific knowledgebase employed in this case study. Future application of this methodology will enable us to compare pathway resources with respect to the generic properties such resources will need to possess if they are to support automated reasoning.

  10. A case study in pathway knowledgebase verification.

    Science.gov (United States)

    Racunas, Stephen A; Shah, Nigam H; Fedoroff, Nina V

    2006-04-08

    Biological databases and pathway knowledge-bases are proliferating rapidly. We are developing software tools for computer-aided hypothesis design and evaluation, and we would like our tools to take advantage of the information stored in these repositories. But before we can reliably use a pathway knowledge-base as a data source, we need to proofread it to ensure that it can fully support computer-aided information integration and inference. We design a series of logical tests to detect potential problems we might encounter using a particular knowledge-base, the Reactome database, with a particular computer-aided hypothesis evaluation tool, HyBrow. We develop an explicit formal language from the language implicit in the Reactome data format and specify a logic to evaluate models expressed using this language. We use the formalism of finite model theory in this work. We then use this logic to formulate tests for desirable properties (such as completeness, consistency, and well-formedness) for pathways stored in Reactome. We apply these tests to the publicly available Reactome releases (releases 10 through 14) and compare the results, which highlight Reactome's steady improvement in terms of decreasing inconsistencies. We also investigate and discuss Reactome's potential for supporting computer-aided inference tools. The case study described in this work demonstrates that it is possible to use our model theory based approach to identify problems one might encounter using a knowledge-base to support hypothesis evaluation tools. The methodology we use is general and is in no way restricted to the specific knowledge-base employed in this case study. Future application of this methodology will enable us to compare pathway resources with respect to the generic properties such resources will need to possess if they are to support automated reasoning.

  11. Laryngeal sarcoidosis: a case-control study.

    Science.gov (United States)

    Duchemann, Boris; Lavolé, Armelle; Naccache, Jean-Marc; Nunes, Hilario; Benzakin, Sylvain; Lefevre, Marine; Kambouchner, Marianne; Périé, Sophie; Valeyre, Dominique; Cadranel, Jacques

    2014-10-20

    We undertook a study on a series of laryngeal sarcoidosis (LS), a very rare and often threatening localization to better specify laryngeal manifestations, sarcoidosis clinical expression and long-term follow-up. This was a retrospective case-control study. All LS patients from two French centers were included and compared to sarcoidosis patients without laryngeal localization with two controls for one patient. Twelve consecutive LS patients were recruited between 1993 and 2011. LS revealed sarcoidosis in eight cases (67%). The most common symptoms were hoarseness (77%), inspiratory dyspnea (38%) and dysphagia (38%). Epidemiological characterisics were not different. Extrapulmonary localizations were significantly more common in LS patients than in controls (92% vs. 54%, p=0.02), particularly lupus pernio (25% vs. 0%, p=0.03) and nasosinusal involvement (83% vs. 4%, p<0.01) while thoracic involvement was less frequent (58% vs 100%, p < 0.01). Treatment rates were higher in the LS group (92% vs. 58%, p=0.04), and treatment duration was longer (median: 81 vs. 13 months, p=0.04), with frequent long-term treatment (67%, N=8/12). Two patients underwent surgery. One patient needed temporary tracheostomy during the course of the disease; Remission rates were lower in LS patients (9% vs. 58% at 2 years p<0.01). Eventually, there was no death nor definitive tracheotomy. LS is a rare condition that is often associated to other loco-regional localizations. LS are often difficult to manage. Survival is good but may require a medico-surgical approach.

  12. Histological and Immunohistochemical Characterization of a Case of Endometriosis in a Guinea Pig (Cavia tschudii

    Directory of Open Access Journals (Sweden)

    Alfonso Baldi

    2017-01-01

    Full Text Available Endometriosis is a chronic gynecological disease characterized by the ectopic proliferation of endometrial tissue outside of the uterine cavity. The pathogenesis of this disease is still obscure, and Sampson’s theory of retrograde menstruation is still the most widely accepted explanation. Endometriosis in animals has been so far described not only in baboons and a rhesus macaque but also in dogs and horses that are nonmenstruating animals. In this article, we report the histological and immunohistochemical characterization of the first case of ovarian cystic endometriosis and adenomyosis in a guinea pig. The case presented supports the hypothesis that endometriosis is a disease not at all related to the phenomenon of retrograde menstruation but is a consequence of some alterations in the morphogenesis of the female genital system and therefore it could be found in any mammal. We suggest considering endometriosis among the other pathological phenotypes in animals displaying ovarian and uterine alterations and having a history of difficulties in conceiving.

  13. WRAP Module 1 sampling strategy and waste characterization alternatives study

    Energy Technology Data Exchange (ETDEWEB)

    Bergeson, C.L.

    1994-09-30

    The Waste Receiving and Processing Module 1 Facility is designed to examine, process, certify, and ship drums and boxes of solid wastes that have a surface dose equivalent of less than 200 mrem/h. These wastes will include low-level and transuranic wastes that are retrievably stored in the 200 Area burial grounds and facilities in addition to newly generated wastes. Certification of retrievably stored wastes processing in WRAP 1 is required to meet the waste acceptance criteria for onsite treatment and disposal of low-level waste and mixed low-level waste and the Waste Isolation Pilot Plant Waste Acceptance Criteria for the disposal of TRU waste. In addition, these wastes will need to be certified for packaging in TRUPACT-II shipping containers. Characterization of the retrievably stored waste is needed to support the certification process. Characterization data will be obtained from historical records, process knowledge, nondestructive examination nondestructive assay, visual inspection of the waste, head-gas sampling, and analysis of samples taken from the waste containers. Sample characterization refers to the method or methods that are used to test waste samples for specific analytes. The focus of this study is the sample characterization needed to accurately identify the hazardous and radioactive constituents present in the retrieved wastes that will be processed in WRAP 1. In addition, some sampling and characterization will be required to support NDA calculations and to provide an over-check for the characterization of newly generated wastes. This study results in the baseline definition of WRAP 1 sampling and analysis requirements and identifies alternative methods to meet these requirements in an efficient and economical manner.

  14. WRAP Module 1 sampling strategy and waste characterization alternatives study

    International Nuclear Information System (INIS)

    Bergeson, C.L.

    1994-01-01

    The Waste Receiving and Processing Module 1 Facility is designed to examine, process, certify, and ship drums and boxes of solid wastes that have a surface dose equivalent of less than 200 mrem/h. These wastes will include low-level and transuranic wastes that are retrievably stored in the 200 Area burial grounds and facilities in addition to newly generated wastes. Certification of retrievably stored wastes processing in WRAP 1 is required to meet the waste acceptance criteria for onsite treatment and disposal of low-level waste and mixed low-level waste and the Waste Isolation Pilot Plant Waste Acceptance Criteria for the disposal of TRU waste. In addition, these wastes will need to be certified for packaging in TRUPACT-II shipping containers. Characterization of the retrievably stored waste is needed to support the certification process. Characterization data will be obtained from historical records, process knowledge, nondestructive examination nondestructive assay, visual inspection of the waste, head-gas sampling, and analysis of samples taken from the waste containers. Sample characterization refers to the method or methods that are used to test waste samples for specific analytes. The focus of this study is the sample characterization needed to accurately identify the hazardous and radioactive constituents present in the retrieved wastes that will be processed in WRAP 1. In addition, some sampling and characterization will be required to support NDA calculations and to provide an over-check for the characterization of newly generated wastes. This study results in the baseline definition of WRAP 1 sampling and analysis requirements and identifies alternative methods to meet these requirements in an efficient and economical manner

  15. [Study of 103 cases of odontogenic cysts].

    Science.gov (United States)

    Moctezuma-Bravo, Gustavo Sergio; Magallanes-González, Eduardo

    2009-01-01

    To describe characteristics of odontogenic cysts in a Mexican population. A retrospective study of 103 odontogenic cysts in 86 patients was done. The data were obtained from files of the Pathology Department of a General Hospital. We observed a frequency of the 8.13 % of odontogenic cysts (103) in 1266 pathological studies. The dentigerous cyst 56 % and odontogenic keratocyst 33 % were the most common odontogenic cysts. Sixty one percent of the cysts appeared in the second and third decades of life. In 71 cysts, 42 % appeared in the posterior region jaw, 29 % in the anterior region of the maxilla and 21 % in the posterior region of the maxilla. A 6.7 % developed a recurrence after treatment and a case of keratocyst of posterior region of the maxilla was associated with epidermoid carcinoma. The study included three women with the syndrome of carcinoma of the basal cell nevus, who presented multiple keratocysts. The dentigerous cysts and odontogenic keratocysts were the most frequent odontogenic cysts. They appeared mainly in the second and third decades of life.

  16. Landslide Economics: Concepts and Case Studies

    Science.gov (United States)

    Klose, Martin; Damm, Bodo

    2015-04-01

    Landslide economics is vital for fundamental understanding of landslide risk as dealing with two important topics: (i) impact assessment, either as damage statistics or cost modeling, and (ii) vulnerability assessment, i.e., the study of exposure, sensitivity, and resilience to landslide damage, ideally from both sociotechnical and financial perspective (e.g., Crovelli and Coe, 2009; Wills et al., 2014). Many aspects addressed in landslide economics have direct influence on landslide risk, including: (i) human activity is often a major causative factor of landslides, not only by predisposing or triggering them, but also as a result of inadequate (low-cost) landslide mitigation; (ii) the level of tolerable or acceptable risk, a measure driving a large part of landslide costs in industrialized countries, is highly variable, differing between individuals, public or private organizations, and societies, with its nature being to change over time; and (iii) decision makers are faced with finding the right balance in landslide mitigation, thus need to weight diverse geological and socioeconomic factors that control its effectiveness in both technical and financial terms (e.g., Klose et al., 2014a). A large part of the complexity in assessing landslide risk as measured by economic costs is due to unique problems in understanding of (i) what types of landslide damage affect human activity and infrastructure in which way, (ii) how society contributes and responds to various kinds of damage, and (iii) how landslide damage is valued in monetary terms. Landslide economics shows the potential to take account of these sociocultural factors to the benefit of risk analysis (e.g., Klose et al., 2014b). The present contribution introduces local and regional case studies in which different economic issues of landslide risk are highlighted using the example of public infrastructures in NW Germany. A special focus is on the following topics: (i) risk culture and created risk, (ii

  17. Data Rescue Case Studies from the Cryosphere

    Science.gov (United States)

    Fetterer, F. M.

    2017-12-01

    A simple definition of the cryosphere is "where the world is frozen", or where water takes the form of snow and ice. The cryosphere is shrinking as the Earth warms. Data, particularly old data, document this in often eye-opening fashion. A photograph of Alaska's Muir Glacier taken in 1902 next to one taken in 2005 has impact that a line graph of air temperature anomalies from a weather station can't match, even though temperature data are fundamental to climate research and to understanding the glacier retreat captured in the photographs. Whaling logbooks from the late 1800s, maps of sea ice shared internationally in the 1930s, and satellite images of the polar oceans from the 1960s are not as immediately thought-provoking as are glacier photographs, but when preserved and documented they provide a record of sea ice coverage that is more than 100 years long. We developed a data product from these and other sources that is used in meteorological reanalysis and to answer questions about ice in the Arctic prior to 1978, when commonly used satellite-data-derived sea ice records begin. Preserving glacier photographs and making them available online, and publishing a gridded sea ice data product that builds on the preservation work of others are examples of data rescue projects that benefit scientific research and mobilize knowledge. These and other case studies suggest that even absent secure funding and an organizational setting that supports data rescue, important data make the transition from someone's office to archived and online with metadata because scientists are impassioned about the data they collect and want others to be able to use these data. In these cases from the cryosphere, student interns, collaborations with librarians, and cooperation with colleagues in other data centers have made it possible to preserve data at low cost.

  18. Characterization and evaluation studies on some JAERI dosimetry systems

    International Nuclear Information System (INIS)

    Kojima, T.; Sunaga, H.; Tachibana, H.; Takizawa, H.; Tanaka, R.

    2000-01-01

    Characterization and evaluation studies were carried out on some JAERI dosimetry systems, mainly alanine-ESR, in terms of the influence on the dose response of parameters such as orientation at ESR analysis, and the temperature during irradiation and analysis. Feasibility study for application of these dosimetry systems to electrons with energies lower than 4 MeV and bremsstrahlung (X rays) was also performed parallel to their reliability check through international dose intercomparison. (author)

  19. Case studies on age-management in organisations: report on organisational case studies

    NARCIS (Netherlands)

    Punte, E.; Conen, W.S.; Schippers, J.; Henkens, C.J.I.M.

    2011-01-01

    The acquisition of case studies was thwarted by the economic crisis and the feeling of being ‘over-researched’ by potential organisations. Although organisations in some sectors (e.g. chemical manufacturing) reported the worst part of the economic crisis was behind, many organisations indicated

  20. Case Study: The Mystery of the Seven Deaths--A Case Study in Cellular Respiration

    Science.gov (United States)

    Gazdik, Michaela

    2014-01-01

    Cellular respiration, the central component of cellular metabolism, can be a difficult concept for many students to fully understand. In this interrupted, problem-based case study, students explore the purpose of cellular respiration as they play the role of medical examiner, analyzing autopsy evidence to determine the mysterious cause of death…

  1. Spatial Modeling of Geometallurgical Properties: Techniques and a Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Deutsch, Jared L., E-mail: jdeutsch@ualberta.ca [University of Alberta, School of Mining and Petroleum Engineering, Department of Civil and Environmental Engineering (Canada); Palmer, Kevin [Teck Resources Limited (Canada); Deutsch, Clayton V.; Szymanski, Jozef [University of Alberta, School of Mining and Petroleum Engineering, Department of Civil and Environmental Engineering (Canada); Etsell, Thomas H. [University of Alberta, Department of Chemical and Materials Engineering (Canada)

    2016-06-15

    High-resolution spatial numerical models of metallurgical properties constrained by geological controls and more extensively by measured grade and geomechanical properties constitute an important part of geometallurgy. Geostatistical and other numerical techniques are adapted and developed to construct these high-resolution models accounting for all available data. Important issues that must be addressed include unequal sampling of the metallurgical properties versus grade assays, measurements at different scale, and complex nonlinear averaging of many metallurgical parameters. This paper establishes techniques to address each of these issues with the required implementation details and also demonstrates geometallurgical mineral deposit characterization for a copper–molybdenum deposit in South America. High-resolution models of grades and comminution indices are constructed, checked, and are rigorously validated. The workflow demonstrated in this case study is applicable to many other deposit types.

  2. Case of prostate cancer with anterior localization multiparametric MRI study

    International Nuclear Information System (INIS)

    Georgiev, A.

    2016-01-01

    Prostate cancer most often originates from acinar epithelium. Most of the clinically palpable carcinomas are located predominantly in the rear/dorzo-lateraI zones of the gland, but the tumors in the transition zone anatomical may spread to the periphery. The detection of a neoplastic process in the front parts of the gland is rare and poses difficulties in diagnosis. We present a rare case of anterior location of prostate carcinoma with invasion of bladder, blood vessels and seminal vesicles. At present, diagnosis of prostate cancer in most men is demonstrated by elevated serum levels of prostate-specific antigen (PSA), or positive rectal examination or ultrasonography. Multi parametric MR study is a promising method for detecting prostate cancer. When used in conjunction with PSA values and rectal examination, MRI is increasingly accepted as a standard for the diagnosis and characterization of prostate carcinoma. Key words; Prostate Cancer. Anterior Localization. Multi Parametric MRI

  3. Evaluation of E-learning Platforms: a Case Study

    Directory of Open Access Journals (Sweden)

    Cristina POP

    2012-01-01

    Full Text Available In the recent past, a great number of e-learning platforms have been introduced on the market showing different characteristics and services. These platforms can be evaluated using multiple criteria and methods. This paper proposes a list of selected quality criteria for describing, characterizing and selecting e-learning platform. These criteria were designed based on e-learning standards. I also propose a mathematical model to determine the probability that a student uses an e-learning platform based on the factors (criteria that determine the quality of the platform and the socio-demographic variables of the student. The case study presented is an application of the model and the input data, intermediate calculations and final results were processed using SAS (Statistical Analysis Software.

  4. BOOK REVIEW: Case Studies in Knowledge Management

    Directory of Open Access Journals (Sweden)

    Reviewed by Dr. Adnan BOYACI

    2005-10-01

    Full Text Available 161Case Studies in Knowledge ManagementEdited by Murray JennexHersley: PA: Idea Group, 2005, pp. 372, ISBN 1-59140-352-9Reviewed by Dr. Adnan BOYACIAnadolu UniversityEskişehir-TurkeyKnowledge management (KM as a structured system and the way to the effectiveness isrelatively new field for the contemporary organizations functioning in different andcompetitive domain of public and private sectors in terms of getting optimal effectivenessunderlined by the concepts such as quality, productivity…etc. Because of the growingimportance and the popularity of the KM either as a research topic or specialized coursesubject, a crucial need for understanding, conceptualization and implementation of KM asa system has emerged since the mid 1990’s. In this sense, the book contributes criticallyto fill the gap between theory and implementation as a teaching material.This edited book is published by Idea Group Publishing. The book has twenty chaptersdivided into seven sections. In addition to a section of authors’ biography contributing thebook and an index, there is a preface that the basic terms and key concepts underliningthe cases discussed following chapters, which is explained in a schematized way.Besides the editor, total of 47 authors have contributed to the book. These authors arefrom different countries, academic backgrounds, and institutions. Although approximatelyone third of the authors are from USA, the rest of the authors are from Canada, England,Austria, Germany, Australia, New Zealand, Egypt, Bahrain and China. The authorsrepresent a variety of universities, private companies, and military institutions. Most ofthem have strong professional backgrounds, which help them address the issues bothfrom theoretical and practical perspectives. Contributions of authors having differentbackgrounds and institutions enable the book to have very comprehensive spectrum andthis makes the book attractive practically for those working different sectors

  5. Odontoma: a retrospective study of 73 cases

    International Nuclear Information System (INIS)

    An, Seo Young; An, Chang Hyeon; Choi, Karp Shik

    2012-01-01

    The purpose of the present study was to retrospectively evaluate the clinical findings and treatment results for impacted permanent teeth associated with odontomas. We retrospectively investigated 73 odontomas in 72 patients who visited Kyungpook National University Dental Hospital from April 2004 through November 2011. The study was performed using medical records, panoramic radiographs, and pathological reports. Data gathered included age, gender, location, chief complaints, effects on dentition, and treatment of odontoma and the impacted tooth associated with odontoma. Most compound odontomas (46.7%) were found in the second decade and complex odontomas were not related to age. Odontomas showed no gender predilection. Fifty-five cases (75.3%) of odontomas were detected on routine dental radiographs. Sixty percent of compound odontomas occurred in the canine area and 57.1% of complex odontomas in the molar areas. Impaction of permanent teeth (61.6%) was the most common complication on the adjacent teeth. Most odontomas (84.9%) were removed surgically and impacted permanent teeth were managed by surgical removal (53.2%), orthodontic treatment (25.5%), or surgical repositioning (6.4%). There was a statistically significant relation between age and preservation of the impacted permanent teeth associated with odontomas (p<0.01). Early detection and treatment of odontomas increase the possibility of preservation of the impacted tooth. Therefore, it would be suggested that periodic panoramic examination during the first and second decade of life might be beneficial for the early detection and better prognosis of odontomas.

  6. (Case Study: Wastewater Pump Station of Khoramabad

    Directory of Open Access Journals (Sweden)

    Masoud Taheriyoun

    2014-10-01

    Full Text Available Evaluation of a Biofilter System for Removal of Hydrogen Sulfide Gas (Case Study: Wastewater Pump Station of Khorramabad Abstract The biofilter system is one of the methods commonly used for the removal of hydrogen sulfide as the main source of odors emitted from wastewater facilities. The system is based on using the contaminant material as bedding to feed microorganisms. To achieve the desirable removal efficiency, it is, therefore, essential to create the proper conditions for the bacteria to grow on the bedding. In this study, a pilot-scale biofilter made of compost and woodchip (with a compost/woodchip ratio of 5:1 was used as the bedding material at Khorrmabad wastewater pumping station to investigate the performance of the system under real conditions. The experiment was carried out over 75 days during which time the input and output H2S concentrations were measured on a regular basis. Moisture was adjusted between 40% and 60% throughout the experiment to provide optimal conditions for bacterial growth. The results showed that the concentration of H2S emitted from the pumping station during 24 hours varied greatly between 0 and 48 PPM. The maximum adsorption capacity of the biological bedding was recorded at 2.874 g/m3.hr and the mean efficiency of H2S removal including the startup time was 89%. The mean performance efficiency during the biological activity after the startup was recorded at 98%.

  7. Odontoma: a retrospective study of 73 cases

    Energy Technology Data Exchange (ETDEWEB)

    An, Seo Young; An, Chang Hyeon; Choi, Karp Shik [School of Dentistry, Kyungpook National University, Daegu (Korea, Republic of)

    2012-06-15

    The purpose of the present study was to retrospectively evaluate the clinical findings and treatment results for impacted permanent teeth associated with odontomas. We retrospectively investigated 73 odontomas in 72 patients who visited Kyungpook National University Dental Hospital from April 2004 through November 2011. The study was performed using medical records, panoramic radiographs, and pathological reports. Data gathered included age, gender, location, chief complaints, effects on dentition, and treatment of odontoma and the impacted tooth associated with odontoma. Most compound odontomas (46.7%) were found in the second decade and complex odontomas were not related to age. Odontomas showed no gender predilection. Fifty-five cases (75.3%) of odontomas were detected on routine dental radiographs. Sixty percent of compound odontomas occurred in the canine area and 57.1% of complex odontomas in the molar areas. Impaction of permanent teeth (61.6%) was the most common complication on the adjacent teeth. Most odontomas (84.9%) were removed surgically and impacted permanent teeth were managed by surgical removal (53.2%), orthodontic treatment (25.5%), or surgical repositioning (6.4%). There was a statistically significant relation between age and preservation of the impacted permanent teeth associated with odontomas (p<0.01). Early detection and treatment of odontomas increase the possibility of preservation of the impacted tooth. Therefore, it would be suggested that periodic panoramic examination during the first and second decade of life might be beneficial for the early detection and better prognosis of odontomas.

  8. Anorexia in the Adolescence - case study

    Directory of Open Access Journals (Sweden)

    Almeida de Paiva, Maria O

    2010-07-01

    Full Text Available Eating disorders lead to special biological and psychological states. The result of the total lack of food is treated in a distinct way by anorexia. Nutritionists have thus had difficulty in coming to an agreement on the best therapy to prevent such disorders. First it is essential to understand which treatment aims are and then to attempt to know how the several treatment models used nowadays can reach those aims. Someone who suffers from eating disorders, together with an inner deformation, suffers from too much sensitiveness. In order to solve these problems, one needs a change in the relationship with oneself, with the others and with the world. This study presents a teenager’s case study – Anorexia. Is, in fact, a problem that society faces and can’t ignore. Many youngsters have already died and others are following their steps. But there are also those ones that succeeded in overcoming the problem and now are reporting their stories.

  9. Assembling a Case Study Tool Kit: 10 Tools for Teaching with Cases

    Science.gov (United States)

    Prud'homme-Généreux, Annie

    2017-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. The author shares the strategies and tools that teachers can use to manage a case study classroom effectively.

  10. CROSSFIT – mental training. Case study

    Directory of Open Access Journals (Sweden)

    Beata Rolak

    2017-08-01

    Full Text Available Introduction: CrossFit is a challenging sport. It enforces full engagement of the athlete in every move during every training session. CrossFit teaches perseverance, discipline and respect. Sports psychology allows for in-depth analysis of trainings or competitions. The athlete can better prepare himself for what he may face, both on the mistakes made and on success. Regular mental training supports the athlete's ability to be successful in sports. The aim of the study: The purpose of this paper was to demonstrate the relationship between mental training - here mainly focused on concentration, self-confidence and imagery,  CrossFit and sports performance. Material and the method: This paper is a case study. The subject of the study was a male - 30 years old, training crossfit, with the 3-year training experience. Meeting  period with the subject male was conducted for 2 months. Before and after the meeting period there were used below mentioned methods: Sports Confidence Inventory (TSCI-PL; The Sport Anxiety Scale (SAS; The Imagination in Sport Questionnaire; The Sport  Orientation Questionnaire (SOQ and the profile of skills.   Results: There was a noticeable increase of the results in the questionnaires: Sports Confidence Inventory (TSCI-PL; The Imagination in Sport Questionnaire; The Sport  Orientation Questionnaire (SOQ questionnaire for the self-confidence (TSCI-PL.  The Sport Anxiety Scale (SAS there was an increase of the results regarding the somatic anxiety and worrying also there was a decrease in the scale of distraction. Conclusion: The meeting period turned out to be effective, however the mental training requires regularity and longevity in order to maintain consistency and repeatability of behavior.

  11. Teaching microbiological food safety through case studies

    Directory of Open Access Journals (Sweden)

    Florence Dubois-Brissonnet

    2015-10-01

    Full Text Available Higher education students usually ask for more training based on case studies. This was addressed by designing a specific food safety module (24 hours in which students were shown how to predict microbiological risks in food products i.e. they were asked to determine product shelf-life according to product formulation, preservation methods and consumption habits using predictive microbiology tools. Working groups of four students first identified the main microbiological hazards associated with a specific product. To perform this task, they were given several documents including guides for good hygiene practices, reviews on microbiological hazards in the food sector, flow sheets, etc…  After three-hours of work, the working groups prepared and gave an oral presentation in front of their classmates and professors. This raised comments and discussion that allowed students to adjust their conclusions before beginning the next step of their work. This second step consisted in the evaluation of the safety risk associated with the two major microbiological hazards of the product studied, using predictive microbiology. Students then attended a general lecture on the different tools of predictive microbiology and tutorials (6 hours that made them familiar with the modelling of bacterial growth or inactivation. They applied these tools (9 hours to predict the shelf-life of the studied product according to various scenarios of preservation (refrigeration, water activity, concentration of salt or acid, modified atmosphere, etc… and/or consumption procedures (cooking. The module was concluded by oral presentations of each working group and included student evaluation (3 hours.

  12. Jazz improvisers’ shared understanding: A case study

    Directory of Open Access Journals (Sweden)

    Michael F. Schober

    2014-08-01

    Full Text Available To what extent and in what arenas do collaborating musicians need to understand what they are doing in the same way? Two experienced jazz musicians who had never previously played together played three improvisations on a jazz standard (It Could Happen to You on either side of a visual barrier. They were then immediately interviewed separately about the performances, their musical intentions, and their judgments of their partner’s musical intentions, both from memory and prompted with the audiorecordings of the performances. Statements from both (audiorecorded interviews as well as statements from an expert listener were extracted and anonymized. Two months later, the performers listened to the recordings and rated the extent to which they endorsed each statement. Performers endorsed statements they themselves had generated more often than statements by their performing partner and the expert listener; their overall level of agreement with each other was greater than chance but moderate to low, with disagreements about the quality of one of the performances and about who was responsible for it. The quality of the performances combined with the disparities in agreement suggest that, at least in this case study, fully shared understanding of what happened is not essential for successful improvisation. The fact that the performers endorsed an expert listener’s statements more than their partner’s argues against a simple notion that performers’ interpretations are always privileged relative to an outsider’s.

  13. Comparative economic analysis: Anaerobic digester case study

    International Nuclear Information System (INIS)

    Lusk, P.D.

    1991-01-01

    An economic guide is developed to assess the value of anaerobic digesters used on dairy farms. Two varieties of anaerobic digesters, a conventional mixed-tank mesophilic and an innovative earthen psychrophilic, are comparatively evaluated using a cost-effectiveness index. The two case study examples are also evaluated using three other investment merit statistics: simple payback period, net present value, and internal rate of return. Life-cycle savings are estimated for both varieties, with sensitivities considered for investment risk. The conclusion is that an earthen psychrophilic digester can have a significant economic advantage over a mixed-tank mesophilic digester because of lower capital cost and reduced operation and maintenance expenses. Because of this economic advantage, additional projects are being conducted in North Carolina to increase the rate of biogas utilization. The initial step includes using biogas for milk cooling at the dairy farm where the existing psychrophilic digester is located. Further, a new project is being initiated for electricity production with thermal reclaim at a swine operation

  14. CFD analysis for road vehicles - case study

    Directory of Open Access Journals (Sweden)

    Eugen Mihai NEGRUS

    2011-09-01

    Full Text Available This is a case study on the influence of the lower part of road vehicles on the global drag characteristics. Reducing overall drag by redesigning the lower part of the road vehicles has a potential of almost 20% in the overall drag breakdown, mainly due to the viscous effects and the fluidic interaction of the flow under the car with the typical bluff body flow pattern behind the vehicle. A special parameterization is proposed for the global shape of the sedan car, with respect to the lower part of the body, taking into account most of the specificities of the system. For such a complex interaction, CFD analysis is probably the only efficient tool in order to assess specific design parameterization of a generic car shape. Building on the credibility of such instruments is one of the major goals of this paper. Also, with respect to a target sedan car configuration, examples of successful design strategies are presented. Based on the CFD results, possible strategies to be used in order to reduce viscous drag and global drag characteristics are proposed.

  15. Deep Energy Retrofits - Eleven California Case Studies

    Energy Technology Data Exchange (ETDEWEB)

    Less, Brennan [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Fisher, Jeremy [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Walker, Iain [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2012-10-01

    This research documents and demonstrates viable approaches using existing materials, tools and technologies in owner-conducted deep energy retrofits (DERs). These retrofits are meant to reduce energy use by 70% or more, and include extensive upgrades to the building enclosure, heating, cooling and hot water equipment, and often incorporate appliance and lighting upgrades as well as the addition of renewable energy. In this report, 11 Northern California (IECC climate zone 3) DER case studies are described and analyzed in detail, including building diagnostic tests and end-use energy monitoring results. All projects recognized the need to improve the home and its systems approximately to current building code-levels, and then pursued deeper energy reductions through either enhanced technology/ building enclosure measures, or through occupant conservation efforts, both of which achieved impressive energy performance and reductions. The beyond-code incremental DER costs averaged $25,910 for the six homes where cost data were available. DERs were affordable when these incremental costs were financed as part of a remodel, averaging a $30 per month increase in the net-cost of home ownership.

  16. Willowglen Systems Inc. : 8 case studies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    The various supervisory control and data acquisition (SCADA) systems designed by Willowglen Systems Inc. were described. The company provides custom SCADA technology products, automation systems, and technical services for various applications. Their remote terminal units (RTUs) were designed to have a very low power consumption rate, and can be operated from any power source. The company has also designed integrated metering and communications solutions for remote locations. The following 8 case studies of Willowglen System solutions were highlighted: (1) a SCADA system designed for the Northwest Territories Power Corporation, (2) a system of RTUs installed at the Shell Canada Ltd. Caroline Gas Complex, (3) a SCADA system designed to monitor a natural gas pipeline, (4) a SCADA system designed to monitor a transmission pipeline and distribution system in Singapore, (5) RTUs designed to monitor gas dehydration units in Bahrain, (6) a SCADA system designed for a refined petroleum products pipeline, (7) a SCADA system installed at an electric power utility in New Brunswick, and (8) a tank gauging system designed for a large oil refinery in Alberta. 7 figs.

  17. Environmental injustice: case studies from the South

    International Nuclear Information System (INIS)

    Cifuentes, Enrique; Frumkin, Howard

    2007-01-01

    We selected three case studies to illustrate environmental injustice issues in the South. These examples relate to migrant agricultural workers, the maquiladora industry and artisanal mining, while reviewing some of the major mechanisms involved, e.g. multinational corporations, the development of free trade zones, multilateral free trade agreements and the export of hazards. A series of strategies are discussed in order to address environmental injustice and health disparities that exist on a global scale. Some of the recommendations involve policy initiatives; others, such as research and mentorship, fall within the traditional domain of public health practice. In this paper, special attention is given to concerned environmental and occupational health professionals using evidence-based data for advocacy. For lasting changes to be made, however, stronger institutions and legislation are required. Those who have the 'right to know' about environmental injustice issues include communities of concern, workers' representatives and lawyers. Government officials and company officials may eventually work on the basis of conflict resolution, compensation and remediation, to quote some examples. Systematic approaches to protect both the environment and public health must be updated

  18. Hyperamonemia in children. Study of 72 cases

    Directory of Open Access Journals (Sweden)

    Jiménez Pérez Mario

    2014-07-01

    Full Text Available Hyperammonemia (HA is a metabolic emergency, and when not diagnosed and treated in a timely manner leads to severe neuro- logical damage and/ or death. HA may have multiple origins, but the EIM are one of the causes that should always be suspected. The objective of this work is to make a clinical description of the causes of HA in a sample of patients from the National Institute of Pediatrics (INP, to know the proportion of patients with HA in which could confirm the presence of an inborn error of metabolism (IEM. We found 72 patients with HA in the past 10 years, of whom 11 were patients already known to have an IEM and 61 with unknown cause; Of the latter, 46% of patients underwent metabolic studies (amino acids quantification, organic acids analysis and orotic acid quantification and in 14 cases (30% an IEM was diagnosed. The clinical symptoms most frequently observed were neurological (seizures, drowsiness, lethargy, irritability, developmental delay, and hypotonia stupor, etc., followed by digestive disturbances such as vomiting and refusal to eat. Urea cycle disorders, aminoacidopathies and organic acidemias were diagnosed, so the management and treatment of these should be known by the pediatricians, especially those dedicated to emergencies.

  19. Jazz improvisers' shared understanding: a case study.

    Science.gov (United States)

    Schober, Michael F; Spiro, Neta

    2014-01-01

    To what extent and in what arenas do collaborating musicians need to understand what they are doing in the same way? Two experienced jazz musicians who had never previously played together played three improvisations on a jazz standard ("It Could Happen to You") on either side of a visual barrier. They were then immediately interviewed separately about the performances, their musical intentions, and their judgments of their partner's musical intentions, both from memory and prompted with the audiorecordings of the performances. Statements from both (audiorecorded) interviews as well as statements from an expert listener were extracted and anonymized. Two months later, the performers listened to the recordings and rated the extent to which they endorsed each statement. Performers endorsed statements they themselves had generated more often than statements by their performing partner and the expert listener; their overall level of agreement with each other was greater than chance but moderate to low, with disagreements about the quality of one of the performances and about who was responsible for it. The quality of the performances combined with the disparities in agreement suggest that, at least in this case study, fully shared understanding of what happened is not essential for successful improvisation. The fact that the performers endorsed an expert listener's statements more than their partner's argues against a simple notion that performers' interpretations are always privileged relative to an outsider's.

  20. Case study : a transformer repair facility

    Energy Technology Data Exchange (ETDEWEB)

    Jerade, L. [Jacques Whitford Environment Ltd., Vancouver, BC (Canada)

    2006-07-01

    Polychlorinated biphenyls (PCBs) are synthetic chemical compounds consisting of chlorine, carbon and hydrogen. They are very stable, fire resistant, do not conduct electricity and have low volatility at normal temperatures. They were mainly used as a cooling and insulating fluid for industrial transformers and capacitors. Some of the same properties that made PCBs so widely used, also make them environmentally hazardous, especially their extreme resistance to chemical and biological breakdown by natural processes in the environment. Typical chemicals associated with the presence of PCB oils are chlorobenzene, lead, xylene, and petroleum hydrocarbons. A case study of a transformer repair facility was discussed along with its soil and groundwater remediation. This presentation discussed the delineation program for the site which operated as a repair facility of PCB-containing transformers from 1968 until 1998. The property was bought by Siemens Canada Ltd. in 1998 and was sold in 2004. As part of the purchasing agreement, a Certificate of Compliance from the British Columbia Ministry of Environment was required. Remediation work was therefore needed. The presentation also covered: zones of contamination and contaminants of concern, soil impacts, groundwater impacts, and an evaluation of remediation options. In-situ treatment of soil with hydrogen peroxide and the selected remedial option were discussed. A soil economic analysis was also conducted. Last, challenges, solutions, and conclusions were presented. tabs., figs.

  1. Hybrid Risk Management Methodology: A Case Study

    Directory of Open Access Journals (Sweden)

    Jacky Siu-Lun Ting

    2009-10-01

    Full Text Available Risk management is a decision-making process involving considerations of political, social, economic and engineering factors with relevant risk assessments relating to a potential hazard. In the last decade, a number of risk management tools are introduced and employed to manage and minimize the uncertainty and threats realization to the organizations. However, the focus of these methodologies are different; in which companies need to adopt various risk management principles to visualize a full picture of the organizational risk level. Regarding to this, this paper presents a new approach of risk management that integrates Hierarchical Holographic Modeling (HHM, Enterprise Risk Management (ERM and Business Recovery Planning (BCP for identifying and assessing risks as well as managing the consequences of realized residual risks. To illustrate the procedures of the proposed methodology, a logistic company ABC Limited is chosen to serve as a case study Through applying HHM and ERM to investigate and assess the risk, ABC Limited can be better evaluated the potential risks and then took the responsive actions (e.g. BCP to handle the risks and crisis in near future.

  2. Environmental injustice: case studies from the South

    Science.gov (United States)

    Cifuentes, Enrique; Frumkin, Howard

    2007-10-01

    We selected three case studies to illustrate environmental injustice issues in the South. These examples relate to migrant agricultural workers, the maquiladora industry and artisanal mining, while reviewing some of the major mechanisms involved, e.g. multinational corporations, the development of free trade zones, multilateral free trade agreements and the export of hazards. A series of strategies are discussed in order to address environmental injustice and health disparities that exist on a global scale. Some of the recommendations involve policy initiatives; others, such as research and mentorship, fall within the traditional domain of public health practice. In this paper, special attention is given to concerned environmental and occupational health professionals using evidence-based data for advocacy. For lasting changes to be made, however, stronger institutions and legislation are required. Those who have the 'right to know' about environmental injustice issues include communities of concern, workers' representatives and lawyers. Government officials and company officials may eventually work on the basis of conflict resolution, compensation and remediation, to quote some examples. Systematic approaches to protect both the environment and public health must be updated.

  3. MOTION TO CHANGE VENUE. CASE STUDY

    Directory of Open Access Journals (Sweden)

    Dragoş Lucian Rădulescu

    2015-11-01

    Full Text Available Change of venue is a remedy offered to a party, which in case of legitimate grounds for suspicion or public safety may require that proceedings belong to another court than the court first seized. But change of venue is not based on a case of material or territorial lack of jurisdiction of the court, taking into account exceptional circumstances or impartiality doubt regarding the case. Thus, article 140 of the Code of Civil Procedure stipulates the possible causes of change of venue, including further issues that will determine jurisdiction to hear by the courts of control.

  4. Uncertainty and Variability in Physiologically-Based Pharmacokinetic (PBPK) Models: Key Issues and Case Studies (Final Report)

    Science.gov (United States)

    EPA announced the availability of the final report, Uncertainty and Variability in Physiologically-Based Pharmacokinetic (PBPK) Models: Key Issues and Case Studies. This report summarizes some of the recent progress in characterizing uncertainty and variability in physi...

  5. Guidelines for Conducting Positivist Case Study Research in Information Systems

    Directory of Open Access Journals (Sweden)

    Graeme Shanks

    2002-11-01

    Full Text Available The case study research approach is widely used in a number of different ways within the information systems community. This paper focuses on positivist, deductive case study research in information systems. It provides clear definitions of important concepts in positivist case study research and illustrates these with an example research study. A critical analysis of the conduct and outcomes of two recently published positivist case studies is reported. One is a multiple case study that validated concepts in a framework for viewpoint development in requirements definition. The other is a single case study that examined the role of social enablers in enterprise resource planning systems implementation. A number of guidelines for successfully undertaking positivist case study research are identified including developing a clear understanding of key concepts and assumptions within the positivist paradigm; providing clear and unambiguous definitions of the units and interactions when using any theory; carefully defining the boundary of the theory used in the case study; using hypotheses rather than propositions in the empirical testing of theory; using fuzzy or probabilistic propositions in recognising that reality can never be perfectly known; selecting case studies carefully, particularly single case studies; and recognising that generalisation from positivist, single case studies is inherently different from generalisation from single experiments. When properly undertaken, positivist, deductive case study research is a valuable research approach for information systems researchers, particularly when used within pluralist research programs that use a number of different research approaches from different paradigms.

  6. Bilingual education in Slovakia: A Case Study

    Directory of Open Access Journals (Sweden)

    Silvia Pokrivčáková

    2013-06-01

    Full Text Available Bilingual education is one of the areas in contemporary education that brings out some important controversies (philosophical, conceptual, sociological, political, economical, etc. and thus calls for extensive and intensive debate. Bilingual education in Europe (and here the European Union countries are meant has gained a very different status, due to the general European policy of developing language diversity and promoting “European plurilingualism and multilingualism”. In Slovakia, one of the younger members of the EU, bilingual education became an extraordinarily popular instrument for the fulfilment of this task.  Since the specifically defined topic of bilingual education and its current status in Slovakia has not been studied and systematically reviewed yet, the research presented in this paper was designed as a single-phenomenon revelatory case study investigating seven research areas: reflection of bilingual education in school legislation and state pedagogical documents, purposes of bilingual education in Slovakia, its organization (levels and types of schools, foreign languages incorporated, teachers, structure of bilingual schools curricula, types of bilingual education applied at Slovak bilingual schools, and how bilingual education is both reflected in and saturated by the latest research findings. The conclusions presented in the paper were collected from multiple sources: state curriculum, statistical data published by the Slovak Ministry of Education or its partner institutions, international treaties on establishing and supporting bilingual sections of schools, bilingual schools curricula, interviews with school directors, teachers, and learners, direct observations at bilingual schools, research studies and research reports, etc. In the conclusion, bilingual education in Slovakia is identified as a unique, dynamically developing system which is both significantly shaped by the foreign language education policy promoted by

  7. Jane: A Case Study in Anorexia Nervosa.

    Science.gov (United States)

    Willingham, Barbara

    1988-01-01

    The article reports the case history of a 15-year-old Australian girl with anorexia nervosa. Information is also given on prevalence, causes, definitions, and treatments including hospitalization, co-therapy, psychotherapy, behavior modification, family therapy, and counseling. (DB)

  8. Y-12 old salvage yard scrap metal characterization study

    International Nuclear Information System (INIS)

    Anderson, L.M.; Melton, S.G.; Shaw, S.S.

    1993-11-01

    The purpose of the Y-12 Old Salvage Yard scrap metal Characterization Study is to make conservative estimates of the quantities of total uranium and the wt % 235 U contained in scrap metal. The original project scope included estimates of thorium, but due to the insignificant quantities found in the yards, thorium was excluded from further analysis. Metal in three of the four Y-12 scrap metal yards were characterized. The scrap metal yard east of the PIDAS fence is managed by the Environmental Restoration Program and therefore was not included in this study. For all Y-12 Plant scrap metal shipments, Waste Transportation, Storage, and Disposal (WTSD) personnel must complete a Request for Authorization to Ship Nuclear Materials, UCN-16409, which requires the grams of total uranium, the wt % 235 U, and the grams of 235 U contained in the shipment. This information is necessary to ensure compliance with Department of Transportation regulations, as well as to ensure that the receiving facility is adhering to its operating license. This characterization study was designed to provide a technical basis for determining these necessary radioactive quantities

  9. Case Study Research in Software Engineering Guidelines and Examples

    CERN Document Server

    Runeson, Per; Rainer, Austen; Regnell, Bjorn

    2012-01-01

    Based on their own experiences of in-depth case studies of software projects in international corporations, in this book the authors present detailed practical guidelines on the preparation, conduct, design and reporting of case studies of software engineering.  This is the first software engineering specific book on the case study research method.

  10. A study of acute expired cases with intraventricular hemorrhage

    International Nuclear Information System (INIS)

    Ikeda, Yukio; Higuchi, Hiroshi; Ueda, Kenji; Kobayashi, Shiro; Yajima, Kouzo

    1981-01-01

    Prior to the introduction of the CT scan, the diagnosis of intraventricular hemorrhage (IVH) was very difficult. The CT scan has, though, been recognized to be extremely informative in the evaluation of IVH. During the first three years we have had experience with 91 cases of IVH diagnosed by the CT scan. Acute death within seven days occurred in 42 of these cases. Hypertension was the most common Acute death within seven days occurred in 42 of these cases. Hypertension was the most common etiological factor, accounting for 18 cases. Cerebral aneurysm was the second most common cause, accounting for 10 cases. Head injury was seen in 8 cases, while the causes of 4 deaths were unknown. 31 cases were distributed over all ventricles. 30 cases revealed over two cast formations. The presence of IVH in the third and/or the fourth ventricle, which can easily affect the function of the hypothalamus and the brain stem anatomically, was closely correlated with the high mortality rate. The analysis of the CT findings regarding the mechanisms of IVH reveals three types: the direct type, which bleeds directly into ventricles without forming definite intracerebral hematomas; the extension type, which is characterized by extension and rupture from massive intracerebral hematoma, and the reflux type, which is characterized by a reflux of the subarachnoid blood. The prognosis depends on the differences in these mechanisms. (author)

  11. Cases for the Net Generation: An Empirical Examination of Students' Attitude toward Multimedia Case Studies

    Science.gov (United States)

    Sheppard, Michael; Vibert, Conor

    2016-01-01

    Case studies have been an important tool in business, legal, and medical education for generations of students. Traditional text-based cases tend to be self-contained and structured in such a way as to teach a particular concept. The multimedia cases introduced in this study feature unscripted web-hosted video interviews with business owners and…

  12. Teaching Business French through Case Studies: Presentation of a Marketing Case.

    Science.gov (United States)

    Federico, Salvatore; Moore, Catherine

    The use of case studies as a means for teaching business French is discussed. The approach is advocated because of the realism of case studies, which are based on actual occurrences. Characteristics of a good case are noted: it tells a story, focuses on interest-arousing issues, is set in the past 10 years, permits empathy with the main…

  13. Case Study: What Makes a Good Case, Revisited: The Survey Monkey Tells All

    Science.gov (United States)

    Herried, Clyde Freeman; Prud'homme-Genereux, Annie; Schiller, Nancy A.; Herreid, Ky F.; Wright, Carolyn

    2016-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. In this month's issue the authors provide a more definitive answer to the "What Makes a Good Case?" question based on a just-completed Survey Monkey survey given to NCCSTS teachers.

  14. Energy retrofit of commercial buildings. Case study and applied methodology

    Energy Technology Data Exchange (ETDEWEB)

    Aste, N.; Del Pero, C. [Department of Building Environment Science and Technology (BEST), Politecnico di Milano, Via Bonardi 3, 20133 Milan (Italy)

    2013-05-15

    Commercial buildings are responsible for a significant share of the energy requirements of European Union countries. Related consumptions due to heating, cooling, and lighting appear, in most cases, very high and expensive. Since the real estate is renewed with a very small percentage each year and current trends suggest reusing the old structures, strategies for improving energy efficiency and sustainability should focus not only on new buildings, but also and especially on existing ones. Architectural renovation of existing buildings could provide an opportunity to enhance their energy efficiency, by working on the improvement of envelopes and energy supply systems. It has also to be noted that the measures aimed to improve the energy performance of buildings should pay particular attention to the cost-effectiveness of the interventions. In general, there is a lack of well-established methods for retrofitting, but if a case study achieves effective results, the adopted strategies and methodologies can be successfully replicated for similar kinds of buildings. In this paper, an iterative methodology for energy retrofit of commercial buildings is presented, together with a specific application on an existing office building. The case study is particularly significant as it is placed in an urban climatic context characterized by cold winters and hot summers; consequently, HVAC energy consumption is considerable throughout the year. The analysis and simulations of energy performance before and after the intervention, along with measured data on real energy performance, demonstrate the validity of the applied approach. The specifically developed design and refurbishment methodology, presented in this work, could be also assumed as a reference in similar operations.

  15. Increasing transmission capacity : case studies and techniques

    Energy Technology Data Exchange (ETDEWEB)

    Reisdorff, R.A. [Laminated Wood Systems, NE (United States)

    2007-07-01

    Many companies are stretching the capacities of their mature transmission lines as a result of deregulation in the electric utility industry. Since electric utilities are no longer in control of new generation locations or capacities, their mission has changed from supplying electricity to regional customers to that of the movement of power over their grid. There will also be even more pressure to maximize the thermal capacity of existing transmission lines once the regional transmission operators (RTOs) are in place. Various methods including conductor replacement or increasing structure height are available options to accomplish this. This paper discussed the available methods to increase ground clearance, including structure changeouts; pole top extensions; nip and tuck conductor; adding mid-span structures; and raising structures. Because the actual cost of line outages for maintenance of rebuild work will make many present day work procedures obsolete, the industry is changing to methods of safely increasing the existing structure heights without removing the line from service. The paper also presented the Phaiseraiser product which is a patented system, consisting of double steel members that are either single or multiple piece units which are used to support the raised structure. The paper discussed the product development of the Phaiseraiser product, with reference to wood stubs; pier foundation; pole enforcer methodology; testing; designs; and ordering requirements. Last, the paper discussed a custom designed installation tool package developed by Laminated Wood Systems (LWS); LWS structural analysis; estimated cost for Phaiseraiser installation on an h-frame; labor resources and training; maintenance considerations; completed Phaiseraiser projects; and a case study on the Omaha Public Power District. figs.

  16. Zimbabwe's national AIDS levy: A case study.

    Science.gov (United States)

    Bhat, Nisha; Kilmarx, Peter H; Dube, Freeman; Manenji, Albert; Dube, Medelina; Magure, Tapuwa

    2016-01-01

    We conducted a case study of the Zimbabwe National AIDS Trust Fund ('AIDS Levy') as an approach to domestic government financing of the response to HIV and AIDS. Data came from three sources: a literature review, including a search for grey literature, review of government documents from the Zimbabwe National AIDS Council (NAC), and key informant interviews with representatives of the Zimbabwean government, civil society and international organizations. The literature search yielded 139 sources, and 20 key informants were interviewed. Established by legislation in 1999, the AIDS Levy entails a 3% income tax for individuals and 3% tax on profits of employers and trusts (which excluded the mining industry until 2015). It is managed by the parastatal NAC through a decentralized structure of AIDS Action Committees. Revenues increased from inception to 2006 through 2008, a period of economic instability and hyperinflation. Following dollarization in 2009, annual revenues continued to increase, reaching US$38.6 million in 2014. By policy, at least 50% of funds are used for purchase of antiretroviral medications. Other spending includes administration and capital costs, HIV prevention, and monitoring and evaluation. Several financial controls and auditing systems are in place. Key informants perceived the AIDS Levy as a 'homegrown' solution that provided country ownership and reduced dependence on donor funding, but called for further increased transparency, accountability, and reduced administrative costs, as well as recommended changes to increase revenue. The Zimbabwe AIDS Levy has generated substantial resources, recently over US$35 million per year, and signals an important commitment by Zimbabweans, which may have helped attract other donor resources. Many key informants considered the Zimbabwe AIDS Levy to be a best practice for other countries to follow.

  17. Simpson's paradox: A statistician's case study.

    Science.gov (United States)

    Chu, Kevin H; Brown, Nathan J; Pelecanos, Anita; Brown, Anthony Ft

    2018-02-26

    Gender equality and workforce diversity has recently been in the forefront of College discussions. Reasons for the difference between various groups may not be as they initially appeared. The results of comparing the outcome between two groups can sometimes be confounded and even reversed by an unrecognised third variable. This concept is known as Simpson's Paradox, and is illustrated here using a renowned case study on potential gender bias for acceptance to Graduate School at the University of California, Berkeley.  The investigation showed that males were 1.8 times more likely to be admitted to Graduate School than females in 1973. Initially it appeared that women were discriminated against in the selection process. However, when admissions were re-examined at individual Departments of the School, admission tended to be better for women than men in four of six Departments. This contradiction or paradox tells us that the association between admission and gender was dependent upon on Department.  The confounding effect of Department was defined by two characteristics. Firstly, a strong association between Department and admission: some Departments admitted much smaller percentages of applicants than others. Secondly, a strong association between Department and gender: females tended to apply to Departments with lower admission rates.  The explanation of differences between groups can be multifactorial. A search for possible confounders will assist in this understanding. This could apply whenever two groups initially appear to differ, but on closer analysis this difference is either unfounded, or even reversed by reference to a third, confounding variable. © 2018 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

  18. Preliminary Hydrogeologic Characterization Results from the Wallula Basalt Pilot Study

    Energy Technology Data Exchange (ETDEWEB)

    B.P. McGrail; E. C. Sullivan; F. A. Spane; D. H. Bacon; G. Hund; P. D. Thorne; C. J. Thompson; S. P. Reidel; F. S. Colwell

    2009-12-01

    The DOE's Big Sky Regional Carbon Sequestration Partnership has completed drilling the first continental flood basalt sequestration pilot borehole to a total depth (TD) of 4,110 feet on the Boise White Paper Mill property at Wallula, Washington. Site suitability was assessed prior to drilling by the 2007-2008 acquisition, processing and analysis of a four-mile, five-line three component seismic swath, which was processed as a single data-dense line. Analysis of the seismic survey data indicated a composite basalt formation thickness of {approx}8,000 feet and absence of major geologic structures (i.e., faults) along the line imaged by the seismic swath. Drilling of Wallula pilot borehole was initiated on January 13, 2009 and reached TD on April 6, 2009. Based on characterization results obtained during drilling, three basalt breccia zones were identified between the depth interval of 2,716 and 2,910 feet, as being suitable injection reservoir for a subsequent CO2 injection pilot study. The targeted injection reservoir lies stratigraphically below the massive Umtanum Member of the Grande Ronde Basalt, whose flow-interior section possesses regionally recognized low-permeability characteristics. The identified composite injection zone reservoir provides a unique and attractive opportunity to scientifically study the reservoir behavior of three inter-connected reservoir intervals below primary and secondary caprock confining zones. Drill cuttings, wireline geophysical logs, and 31one-inch diameter rotary sidewall cores provided geologic data for characterization of rock properties. XRF analyses of selected rock samples provided geochemical characterizations of the rocks and stratigraphic control for the basalt flows encountered by the Wallula pilot borehole. Based on the geochemical results, the pilot borehole was terminated in the Wapshilla Ridge 1 flow of the Grande Ronde Basalt Formation. Detailed hydrologic test characterizations of 12 basalt interflow

  19. Rehabilitation in locked-in-syndrome – a case study

    Directory of Open Access Journals (Sweden)

    Anna Grabowska

    2017-03-01

    Full Text Available Introduction: The locked-in syndrome is a neurological condition which occurs most often as a result of brainstem stroke, characterized by the presence of sustained eye opening, aphonia or severe hypophonia, quadriplegia or quadriparesis, preserved cognitive functioning, and a primary and elementary code of communication using vertical eye movements or blinking. This illness leads to complete physical disability of the person, accompanied with fully retained mental capability. Case study: The goal of the hereby work is to present a description of a case of a person with the locked-in syndrome, caused by ischemic stroke of the pons and left cerebellar hemisphere. The prognosis of improvement in LIS is bad. The patient has to adapt to the new, difficult situation that will probably accompany him for whole life. The article presents the therapeutic process from the onset through physical rehabilitation,  speech therapy and psychological  therapy until return home. The process requires patience from the patient and therapists and family members. Conclusion: Research in this area is supposed to help in planning of cooperation the entire medical team of doctors, nurses, physiotherapists, social workers, speech therapists and neuropsychologists. Interdisciplinary proceedings can greatly help to achieve even a minimal degree of independence and autonomy.

  20. Case study: FUSRAP in New Jersey (1980-1987)

    International Nuclear Information System (INIS)

    Kannard, J.R.

    1987-01-01

    The State of New Jersey brings to mind a number of images, most of which are associated with its proximity to New York City. It is not strictly, however, a state of big city problems and industrialization. It is a state of striking contrasts; and in a similar way, DOE's Formerly Utilized Sites Remedial Action Program (FUSRAP) in New Jersey is a program of contrasts. FUSRAP in New Jersey consists of five sites, representing 17% of all sites in the FUSRAP program. Two of those sites, Kellex in Jersey City and DuPont in Deepwater, have not been included in recent program activities, and the case study will concentrate only on the other three - one in Middlesex, one in Wayne, and one in Maywood. Each of these is being used as an interim storage site for contaminated material from vicinity properties. Each also represents a distinct stage of completion of interim remedial action. Middlesex is complete, Wayne is nearing completion, and Maywood is still in the characterization stage with some remedial action also having been accomplished. Contrasts range from drastically different attitudes in the public and local government sector to significant differences in quantities of contaminated materials, and the mechanisms by which these migrated to vicinity properties. And, in each case, the main concern on the part of the public is lack of a location for permanent disposal. These issues along with the history, objectives, and accomplishments for each site are discussed