WorldWideScience

Sample records for change precision guided

  1. Precision Machining Technology. Curriculum Guide.

    Science.gov (United States)

    Idaho State Dept. of Education, Boise. Div. of Vocational Education.

    This curriculum guide was developed from a Technical Committee Report prepared with the assistance of industry personnel and containing a Task List which is the basis of the guide. It presents competency-based program standards for courses in precision machining technology and is part of the Idaho Vocational Curriculum Guide Project, a cooperative…

  2. Florida Vocational Program Guide for Basic Precision Machining, Precision Machining.

    Science.gov (United States)

    University of South Florida, Tampa. Dept. of Adult and Vocational Education.

    This program guide has been developed to provide information that will be useful to local school district and community college administrators, instructors, program advisory committee members, regional coordinating councils, and others charged with the responsibility of offering vocational education programs in Florida. It identifies the major…

  3. Arsenal of democracy in the face of change: Precision Guided Munitions (PGMs), their evolution and some economic considerations, Working Paper No. 4

    Energy Technology Data Exchange (ETDEWEB)

    Chester, C.V.

    1990-08-01

    A brief study was made of some of the forces driving the move to Precision Guided Munitions (PGMs), including the quest for military effectiveness, combat experience, and logistic compression. PGMs cost from a few hundred to a few thousand dollars per Kg but are tens to hundreds of times more effective than conventional munitions. A year's peacetime plateau production of each US PGM can be carried by a few C-5 aircraft. Surge quantities of PGMs are within US airlift capabilities, taking some of the risk out of off-shore procurement. The improving capability of antiaircraft PGMs and the escalating cost of combat aircraft (50 to 100-fold in constant dollars since WW II) may bring into question the economic viability of manned attack aircraft. The same may be true to a slightly lesser degree for heavy armored vehicles. 14 refs., 5 tabs.

  4. LandingNav: Terrain Guided Automated Precision Landing Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Phase I effort successfully demonstrated the feasibility of a terrain guided automated precision landing sensor using an innovative multi-field-of-view stereo...

  5. Program Guide for Basic Precision Machining 8754000 (IN48.052300) and Precision Machining MTR0470 (IN48.050300).

    Science.gov (United States)

    University of South Florida, Tampa. Dept. of Adult and Vocational Education.

    This competency-based program guide provides course content information and procedures for secondary schools, postsecondary vocational schools, and community colleges in Florida that conduct programs in basic precision machining and precision machining. The first section is on legal authority, which applies to all vocational education programs in…

  6. AICPA considers changes to Hospital Audit Guide.

    Science.gov (United States)

    Tillett, J W; Titera, W R

    1988-02-01

    The healthcare industry has changed dramatically since the first Hospital Audit Guide was published. As a result, a number of changes to the Guide itself have been proposed. Some of these revisions include widening the scope of the Guide, changes in revenue reporting, and providing guidance in covering risk contracts. PMID:10285690

  7. Precision Agriculture: Changing the Face of Farming

    Science.gov (United States)

    Rickman, D.; Luvall, J.; Mask, P.; Shaw, J.; Kissel, D.; Sullivan, D.

    2003-01-01

    . Just a one percent increase in efficiency is a $2,000,000 change. We all depend on farmers, literally for the bread we eat. No other activity of man even has an impact on the land that farming has. If application of precision agriculture can nelp farmers manage their land better, we all may benefit.

  8. Guiding Oncology Patients Through the Maze of Precision Medicine.

    Science.gov (United States)

    Giuse, Nunzia Bettinsoli; Kusnoor, Sheila V; Koonce, Taneya Y; Naylor, Helen M; Chen, Sheau-Chiann; Blasingame, Mallory N; Anderson, Ingrid A; Micheel, Christine M; Levy, Mia A; Ye, Fei; Lovly, Christine M

    2016-01-01

    As the role of genomics in health care grows, patients increasingly require adequate genetic literacy to fully engage in their care. This study investigated a model for delivering consumer-friendly genetic information to improve understanding of precision medicine using health literacy and learning style principles. My Cancer Genome (MCG), a freely available cancer decision support tool, was used as a testbed. MCG content on a melanoma tumor mutation, BRAF V600E, was translated to a 6th-grade reading level, incorporating multiple learning modalities. A total of 90 patients and caregivers were recruited from a melanoma clinic at an academic medical center and randomized to 3 groups. Group A (control) received an exact copy of text from MCG. Group B was given the same content with hyperlinks to videos explaining key genetic concepts, identified and labeled by the team as knowledge pearls. Group C received the translated content with the knowledge pearls embedded. Changes in knowledge were measured through pre and post questionnaires. Group C showed the greatest improvement in knowledge. The study results demonstrate that providing information based on health literacy and learning style principles can improve patients' understanding of genetic concepts, thus increasing their likelihood of taking an active role in any decision making concerning their health. PMID:27043753

  9. LandingNav: Terrain Guided Automated Precision Landing Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The purpose of the proposed effort is to provide a novel and innovative precision landing sensor (LandingNav) for Mars. LandingNav supports space exploration by...

  10. Dynamic analysis of a linear motion guide having rolling elements for precision positioning devices

    International Nuclear Information System (INIS)

    Linear motion (LM) guides supported by rolling elements can be used to ultra-accurately position precision machines. For accurate positioning, the micro and macro dynamic behavior of the LM guide must be understood, but the research on this subject is rather limited. In this investigation, experiments to reveal the dynamic characteristics of the LM guide were performed and a simplified model to predict the observed dynamics of the LM guide was developed. Several experiments conducted in the present research demonstrated the hysteretic behavior as well as frequency- and force-dependent phenomena of the LM guide. The validity of the proposed modeling method was checked with theoretical and numerical analyses

  11. Changing Classroom Behavior: A Manual for Precision Teaching.

    Science.gov (United States)

    Meacham, Merle L.; Wiesen, Allen E.

    The discussion of Precision Teaching, attempting to integrate humanism and behaviorism (what we know as educators and as behavioral scientists), provides both specific guidelines for teachers concerning positive classroom behavior change, and general directions in which education must go to remain relevant. The concept of Precision Teaching is…

  12. ALTERABLE INTERVAL OPTICAL-ELECTRONIC AUTOCOLLIMATION METHOD FOR STRAIGHTNESS MEASUREMENT OF PRECISION GUIDE

    Institute of Scientific and Technical Information of China (English)

    Xue Zi; Tan Jiubin; Zhao Weiqian; Zhang Heng

    2005-01-01

    Optical-electronic autocollimation method is commonly used to measure straightness of precision guides in engineering application. However, the traditional fixed interval optical-electronic autocollimation method is not suitable for measuring straightness of an air-bearing guide with a long air-bearing bush or a precision straight guide with a long slide-carriage, because the air-bearing bush and the slide-carriage are actually taken as a big bridgeboard bigger than the length of the bridgeboard with the reflector, which is about 1/4~1/2 of total length of the measured guide. If straightness is measured according to the traditional method, only a few points are sampled so that the guide straightness can not be evaluated fully or accurately. In order to solve the problem, an alterable measuring interval method is proposed for straightness measurement based on analyzing the mutual relations and effects among the tilting angle of the reflector, the length of the bridgeboard, the measuring interval and the straightness of the guide. A straightness calculation model is also developed using the method, and the errors stemming from the method proposed are introduced in brief. A precision air-bearing guide with a long air-bearing bush is measured and evaluated using the method proposed, and the actual measurement and evaluation results prove that the method is correct in theory and practical in operation. The method proposed gives an effective and flexible solution to the straightness measurement of the precision guide with long slide-carriage or air-bearing bush in application. It is an extension of the traditional optical-electronic autocollimation method for straightness measurement.

  13. Global change and Canadians: A teacher's guide

    International Nuclear Information System (INIS)

    A report called Global Change and Canadians has been produced by the Royal Society of Canada to answer basic questions being asked about global change issues. A teacher's guide is presented to help teachers make effective use of the report in developing programs with students concerning global change. A basic set of teaching and learning activities related to the major topics in the report is provided, curricular connections between global change topics and school programs are suggested, and some additional resources on global change are listed. The guide is divided into six chapters, each corresponding to the chapters of the global change report. Each chapter contains a summary of the major concepts from the report, some of the learning outcomes that occur when those concepts are addressed, a series of suggested activities or ideas, and a guide for assessing students' abilities relative to the concepts of the chapter. The topics of the chapters cover the nature of global change, the importance of global change to Canada, the causes of global change, the consequences of global change (including climate change and the greenhouse effect), the effects of global change on society, and Canadian responses to global change. 64 refs., 3 figs

  14. A precision of the sequential change point detection

    OpenAIRE

    Ochman-Gozdek, A.; Sarnowski, W; Szajowski, K. J.

    2014-01-01

    A random sequence having two segments being the homogeneous Markov processes is registered. Each segment has his own transition probability law and the length of the segment is unknown and random. The transition probabilities of each process are known and a priori distribution of the disorder moment is given. The decision maker aim is to detect the moment of the transition probabilities change. The detection of the disorder rarely is precise. The decision maker accepts some deviation in estim...

  15. Design of a Remote-controlled and GPS-guided Autonomous Robot for Precision Farming

    Directory of Open Access Journals (Sweden)

    İlker Ünal

    2015-12-01

    Full Text Available Determining variations in fields is important for precision farming applications. Precision farming is used to determine, analyse, and manage factors such as temporal and spatial variability to obtain maximum profit, sustainability, and environmental protection. However, precision farming is excessively dependent on soil and plant test processes. Furthermore, test processes are time-consuming, laborious and expensive. These processes also cannot be performed quickly by humans. For these reasons, autonomous robots should be designed and developed for the detection of field variations and variable-rate applications. In this study, a remote-controlled and GPS-guided autonomous robot was designed and developed, which can be controlled via the 3G internet and is suitable for image-processing applications. The joystick is used to manually remotely control the robot movements in any direction or speed. Real-time video transmission to the remote computer can be accomplished with a camera placed on the vehicle. Navigation software was developed for steering the robot autonomously. In the results of the field test for the navigation software, it was found that the linear target point precision ranged from 10 to 12 cm and the distributed target point precision ranged from 15 to 17 cm.

  16. Precise image-guided irradiation of small animals: a flexible non-profit platform

    Science.gov (United States)

    Tillner, Falk; Thute, Prasad; Löck, Steffen; Dietrich, Antje; Fursov, Andriy; Haase, Robert; Lukas, Mathias; Rimarzig, Bernd; Sobiella, Manfred; Krause, Mechthild; Baumann, Michael; Bütof, Rebecca; Enghardt, Wolfgang

    2016-04-01

    Preclinical in vivo studies using small animals are essential to develop new therapeutic options in radiation oncology. Of particular interest are orthotopic tumour models, which better reflect the clinical situation in terms of growth patterns and microenvironmental parameters of the tumour as well as the interplay of tumours with the surrounding normal tissues. Such orthotopic models increase the technical demands and the complexity of preclinical studies as local irradiation with therapeutically relevant doses requires image-guided target localisation and accurate beam application. Moreover, advanced imaging techniques are needed for monitoring treatment outcome. We present a novel small animal image-guided radiation therapy (SAIGRT) system, which allows for precise and accurate, conformal irradiation and x-ray imaging of small animals. High accuracy is achieved by its robust construction, the precise movement of its components and a fast high-resolution flat-panel detector. Field forming and x-ray imaging is accomplished close to the animal resulting in a small penumbra and a high image quality. Feasibility for irradiating orthotopic models has been proven using lung tumour and glioblastoma models in mice. The SAIGRT system provides a flexible, non-profit academic research platform which can be adapted to specific experimental needs and therefore enables systematic preclinical trials in multicentre research networks.

  17. Pre-flight Functionality Check to Enhance Mission Efficacy of Precision Guided Munitions

    Directory of Open Access Journals (Sweden)

    A. K. Maini

    2009-09-01

    Full Text Available Precision-guided munitions (PGMs, because of their precision strike capability, are used extensively in the modern warfare. The efficacy of the mission is critically dependent on the successful deployment of the weapon. To ensure high level of effectiveness of these sophisticated weapons, these must be tested at regular intervals. Periodic functionality checks of these weapons are carried out using comprehensive characterisation systems. In addition to comprehensive testing, pre-flight functionality checks with the weapon strapped on to the launchplatform using portable test systems should be carried out. These functionality checks, also referred to as serviceability checks, perform Go/No Go testing of the weapon by focusing on one or two vital parameters of the guided weapon. Pre-flight functionality check of PGM allows a quick appraisal on the functional status of the vital operational parameters of relevance to efficacy of the mission. This review highlights the parameters that need to be checked, both for comprehensive testing of these weapons on a periodic basis and also those required for pre-flight functionality or readiness checks. International systems available for the purpose have also been reviewed, vis-à-vis, their capabilities and limitations to perform the two types of tests with particular emphasis on the pre-flight functionality checks with guided weapon in strap-on condition. Some alternative design approaches have also been proposed.Defence Science Journal, 2009, 59(5, pp.459-465, DOI:http://dx.doi.org/10.14429/dsj.59.1547

  18. Precision targeting in guided munition using IR sensor and MmW radar

    Science.gov (United States)

    Sreeja, S.; Hablani, H. B.; Arya, H.

    2015-10-01

    Conventional munitions are not guided with sensors and therefore miss the target, particularly if the target is mobile. The miss distance of these munitions can be decreased by incorporating sensors to detect the target and guide the munition during flight. This paper is concerned with a Precision Guided Munition(PGM) equipped with an infrared sensor and a millimeter wave radar [IR and MmW, for short]. Three-dimensional flight of the munition and its pitch and yaw motion models are developed and simulated. The forward and lateral motion of a target tank on the ground is modeled as two independent second-order Gauss-Markov process. To estimate the target location on the ground and the line-of-sight rate to intercept it an Extended Kalman Filter is composed whose state vector consists of cascaded state vectors of missile dynamics and target dynamics. The line-of-sight angle measurement from the infrared seeker is by centroiding the target image in 40 Hz. The centroid estimation of the images in the focal plane is at a frequency of 10 Hz. Every 10 Hz, centroids of four consecutive images are averaged, yielding a time-averaged centroid, implying some measurement delay. The miss distance achieved by including by image processing delays is 1:45m.

  19. Generic precise augmented reality guiding system and its calibration method based on 3D virtual model.

    Science.gov (United States)

    Liu, Miao; Yang, Shourui; Wang, Zhangying; Huang, Shujun; Liu, Yue; Niu, Zhenqi; Zhang, Xiaoxuan; Zhu, Jigui; Zhang, Zonghua

    2016-05-30

    Augmented reality system can be applied to provide precise guidance for various kinds of manual works. The adaptability and guiding accuracy of such systems are decided by the computational model and the corresponding calibration method. In this paper, a novel type of augmented reality guiding system and the corresponding designing scheme are proposed. Guided by external positioning equipment, the proposed system can achieve high relative indication accuracy in a large working space. Meanwhile, the proposed system is realized with a digital projector and the general back projection model is derived with geometry relationship between digitized 3D model and the projector in free space. The corresponding calibration method is also designed for the proposed system to obtain the parameters of projector. To validate the proposed back projection model, the coordinate data collected by a 3D positioning equipment is used to calculate and optimize the extrinsic parameters. The final projecting indication accuracy of the system is verified with subpixel pattern projecting technique. PMID:27410124

  20. Whole-exome sequencing and clinical interpretation of FFPE tumor samples to guide precision cancer medicine

    Science.gov (United States)

    Allen, Eliezer M. Van; Wagle, Nikhil; Stojanov, Petar; Perrin, Danielle L.; Cibulskis, Kristian; Marlow, Sara; Jane-Valbuena, Judit; Friedrich, Dennis C.; Kryukov, Gregory; Carter, Scott L.; McKenna, Aaron; Sivachenko, Andrey; Rosenberg, Mara; Kiezun, Adam; Voet, Douglas; Lawrence, Michael; Lichtenstein, Lee T.; Gentry, Jeff G.; Huang, Franklin W.; Fostel, Jennifer; Farlow, Deborah; Barbie, David; Gandhi, Leena; Lander, Eric S.; Gray, Stacy W.; Joffe, Steven; Janne, Pasi; Garber, Judy; MacConaill, Laura; Lindeman, Neal; Rollins, Barrett; Kantoff, Philip; Fisher, Sheila A.; Gabriel, Stacey; Getz, Gad; Garraway, Levi A.

    2013-01-01

    Translating whole exome sequencing (WES) for prospective clinical use may impact the care of cancer patients; however, multiple innovations are necessary for clinical implementation. These include: (1) rapid and robust WES from formalin-fixed paraffin embedded (FFPE) tumor tissue, (2) analytical output similar to data from frozen samples, and (3) clinical interpretation of WES data for prospective use. Here, we describe a prospective clinical WES platform for archival FFPE tumor samples. The platform employs computational methods for effective clinical analysis and interpretation of WES data. When applied retrospectively to 511 exomes, the interpretative framework revealed a “long tail” of somatic alterations in clinically important genes. Prospective application of this approach identified clinically relevant alterations in 15/16 patients. In one patient, previously undetected findings guided clinical trial enrollment leading to an objective clinical response. Overall, this methodology may inform the widespread implementation of precision cancer medicine. PMID:24836576

  1. Image-guided precision manipulation of cells and nanoparticles in microfluidics

    Science.gov (United States)

    Cummins, Zachary

    Manipulation of single cells and particles is important to biology and nanotechnology. Our electrokinetic (EK) tweezers manipulate objects in simple microfluidic devices using gentle fluid and electric forces under vision-based feedback control. In this dissertation, I detail a user-friendly implementation of EK tweezers that allows users to select, position, and assemble cells and nanoparticles. This EK system was used to measure attachment forces between living breast cancer cells, trap single quantum dots with 45 nm accuracy, build nanophotonic circuits, and scan optical properties of nanowires. With a novel multi-layer microfluidic device, EK was also used to guide single microspheres along complex 3D trajectories. The schemes, software, and methods developed here can be used in many settings to precisely manipulate most visible objects, assemble objects into useful structures, and improve the function of lab-on-a-chip microfluidic systems.

  2. Precision Medicine and the Changing Landscape of Research Ethics.

    Science.gov (United States)

    Hammer, Marilyn J

    2016-03-01

    President Barack Obama announced the launch of the National Institutes of Health Precision Medicine Initiative® (PMI) in January 2015. Precision medicine includes the concept of individualized or personalized medicine at a more exact level through advances in science and technology, such as genetics and genomics sequencing. Although many disease processes will be investigated through the precision medicine lens for greater understanding and improved treatment responses, oncology research and translation to practice is leading the initiative's debut, referred to as the near-term focus. PMID:26906126

  3. Implementing Strategic Change: A Practical Guide for Business.

    Science.gov (United States)

    Grundy, Tony

    This book is designed to serve as a practical guide to planning and managing change within a business, and as a text for graduate business students studying change strategies. It focuses on the rationale for change, managing the change process, tools for change, creating a strategic vision for change, and checklists for implementing strategic…

  4. Changing the precision of preschoolers' approximate number system representations changes their symbolic math performance.

    Science.gov (United States)

    Wang, Jinjing Jenny; Odic, Darko; Halberda, Justin; Feigenson, Lisa

    2016-07-01

    From early in life, humans have access to an approximate number system (ANS) that supports an intuitive sense of numerical quantity. Previous work in both children and adults suggests that individual differences in the precision of ANS representations correlate with symbolic math performance. However, this work has been almost entirely correlational in nature. Here we tested for a causal link between ANS precision and symbolic math performance by asking whether a temporary modulation of ANS precision changes symbolic math performance. First, we replicated a recent finding that 5-year-old children make more precise ANS discriminations when starting with easier trials and gradually progressing to harder ones, compared with the reverse. Next, we show that this brief modulation of ANS precision influenced children's performance on a subsequent symbolic math task but not a vocabulary task. In a supplemental experiment, we present evidence that children who performed ANS discriminations in a random trial order showed intermediate performance on both the ANS task and the symbolic math task, compared with children who made ordered discriminations. Thus, our results point to a specific causal link from the ANS to symbolic math performance. PMID:27061668

  5. Bismuth sulfide nanorods as a precision nanomedicine for in vivo multimodal imaging-guided photothermal therapy of tumor.

    Science.gov (United States)

    Liu, Jing; Zheng, Xiaopeng; Yan, Liang; Zhou, Liangjun; Tian, Gan; Yin, Wenyan; Wang, Liming; Liu, Ying; Hu, Zhongbo; Gu, Zhanjun; Chen, Chunying; Zhao, Yuliang

    2015-01-27

    Here, we present a precision cancer nanomedicine based on Bi(2)S(3) nanorods (NRs) designed specifically for multispectral optoacoustic tomography (MSOT)/X-ray computed tomography (CT)-guided photothermal therapy (PTT). The as-prepared Bi(2)S(3) NRs possess ideal photothermal effect and contrast enhancement in MSOT/CT bimodal imaging. These features make them simultaneously act as "satellite" and "precision targeted weapon" for the visual guide to destruction of tumors in vivo, realizing effective tumor destruction and metastasis inhibition after intravenous injection. In addition, toxicity screening confirms that Bi(2)S(3) NRs have well biocompatibility. This triple-modality-nanoparticle approach enables simultaneously precise cancer therapy and therapeutic monitoring. PMID:25561009

  6. A Social Science Guide for Communication on Climate Change

    Science.gov (United States)

    St John, C.; Marx, S.; Markowitz, E.

    2014-12-01

    Researchers from the Center for Research on Environmental Decisions (CRED) published "The Psychology of Climate Change Communication: A Guide for Scientists, Journalists, Educators, Political Aides, and the Interested Public" in 2009. This landmark guide provided climate change communicators a synthesis of the social science research that was pertinent to understanding how people think about climate change and how the practice could be improved. In the fall of 2014 this guide will be rereleased, with a new title, and in a partnership between CRED and ecoAmerica. The updated guide addresses how and why Americans respond in certain ways to climate change and explains how communicators can apply best practices to their own work. The guide, which includes research from a range of social science fields including psychology, anthropology, communications, and behavioral economics, is designed to be useful for experienced and novice communicators alike. Included in the guide are strategies to boost engagement, common mistakes to avoid, and best practices that organizations around the world have used to meaningfully engage individuals and groups on climate change. The proposed presentation will provide an overview of the main findings and tips from the 2014 climate change communication guide. It will provide a deeper look at a few of the key points that are crucial for increasing audience engagement with climate change including understanding how identity shapes climate change, how to lead with solutions, and how to bring the impacts of climate change close to home. It will highlight tips for motivating positive behavior change that will lead people down the path toward solutions. Finally, it will address the benefits and challenges associated with producing a communication guide and insight into synthesizing social science research findings into a usable format for a variety of audiences.

  7. Analysis of guide modes in vertical hot ring rolling and their effects on the ring's dimensional precision using FE method

    International Nuclear Information System (INIS)

    In the vertical hot ring rolling (VHRR) process, roundness, outer radius, and width spread are three important indexes to the formed ring's dimensional precision. In this paper, features of the guide modes of the VHRR process, such as single fixed guide mode (SFGM) and single follow-up guide mode (SFUGM), are analyzed to investigate their effects on the ring's dimensional precision. The geometrical models of all the guide modes are then established and reliable three-dimensional coupled thermal-mechanical elastic-plastic FE models of the VHRR process are developed in ABAQUS/Explicit. Some key technologies, such as the guide roller's motion control, are reasonably dealt with. The research results show that: (1) The roundness of the rings rolled by SFUGM is obviously superior to that of the ring rolled by SFGM. (2) With the same feed amount, the outer radius of the ring rolled by SFGM is always larger than that of the rings rolled by SFUGM. (3) During the rolling process of the ring rolled by SFGM, severe eccentricity will exist at the ring's center, which is not obvious in the rolling process of the ring rolled by SFUGM. (4) The average value of width spread of the ring rolled by SFGM is slightly larger than that of the rings rolled by SFUGM. The research results can yield an understanding of some phenomena in the VHRR process. The modeling methods presented in this paper have general significance in the study of the VHRR process of the ring with complex profile

  8. The changing circumstance of atrial fibrillation - progress towards precision medicine.

    Science.gov (United States)

    Camm, A J; Savelieva, I; Potpara, T; Hindriks, G; Pison, L; Blömstrom-Lundqvist, C

    2016-05-01

    The prevalence of atrial fibrillation (AF) in the general population is between 1% and 2% in the developed world and is higher in men than in women. The arrhythmia occurs much more commonly in the elderly, and the estimated lifetime risk of developing AF is one in four for men and women aged 40 years and above. Projected data from multiple population-based studies in the USA and Europe predict a two- to threefold increase in the number of AF patients by 2060. The high lifetime risk of AF and increased longevity underscore the important public health burden posed by this arrhythmia worldwide. AF has multiple aetiologies and a broad variety of presentations. The primary pathologies underlying or promoting the occurrence of AF vary more than for any other cardiac arrhythmia, ranging from autonomic imbalance to organic heart disease and metabolic disorders, such as diabetes mellitus, metabolic syndrome, hyperthyroidism and kidney disease, and lifestyle factors such as smoking, alcohol consumption and participation in endurance sports. Biomarkers are increasingly being investigated and, together with clinical and genetic factors, will eventually lead to a clinically valuable detailed classification of AF which will also incorporate pathophysiological determinants and mechanisms of the arrhythmia. In turn, this will allow the development and application of precision medicine to this troublesome arrhythmia. PMID:27029018

  9. Design of a Remote-controlled and GPS-guided Autonomous Robot for Precision Farming

    OpenAIRE

    İlker ÜNAL; TOPAKCI, Mehmet

    2015-01-01

    Determining variations in fields is important for precision farming applications. Precision farming is used to determine, analyse, and manage factors such as temporal and spatial variability to obtain maximum profit, sustainability, and environmental protection. However, precision farming is excessively dependent on soil and plant test processes. Furthermore, test processes are time-consuming, laborious and expensive. These processes also cannot be performed quickly by humans. For these reaso...

  10. The use of laser altimetry data in Chang'E-1 precision orbit determination

    Science.gov (United States)

    Chang, Sheng-Qi; Huang, Yong; Li, Pei-Jia; Hu, Xiao-Gong; Fan, Min

    2016-09-01

    Accurate altimetric measurement not only can be applied to the calculation of a topography model but also can be used to improve the quality of the orbit reconstruction in the form of crossovers. Altimetry data from the Chang'E-1 (CE-1) laser altimeter are analyzed in this paper. The differences between the crossover constraint equation in the form of height discrepancies and in the form of minimum distances are mainly discussed. The results demonstrate that the crossover constraint equation in the form of minimum distances improves the CE-1 orbit precision. The overlap orbit performance has increased ∼ 30% compared to the orbit using only tracking data. External assessment using the topography model also shows orbit improvement. The results will be helpful for recomputing ephemeris and improving the CE-1 topography model.

  11. Working memory gating mechanisms explain developmental change in rule-guided behavior.

    Science.gov (United States)

    Unger, Kerstin; Ackerman, Laura; Chatham, Christopher H; Amso, Dima; Badre, David

    2016-10-01

    Cognitive control requires choosing contextual information to update into working memory (input gating), maintaining it there (maintenance) stable against distraction, and then choosing which subset of maintained information to use in guiding action (output gating). Recent work has raised the possibility that the development of rule-guided behavior, in the transition from childhood to adolescence, is linked specifically to changes in the gating components of working memory (Amso, Haas, McShane, & Badre, 2014). Given the importance of effective rule-guided behavior for decision making in this developmental transition, we used hierarchical rule tasks to probe the precise developmental dynamics of working memory gating. This mechanistic precision informs ongoing efforts to train cognitive control and working memory operations across typical and atypical development. The results of Experiment 1 verified that the development of rule-guided behavior is uniquely linked to increasing hierarchical complexity but not to increasing maintenance demands across 1st, 2nd, and 3rd order rule tasks. Experiment 2 then investigated whether this developmental trajectory in rule-guided behavior is best explained by change in input gating or output gating. Further, as input versus output gating also tend to correlate with a more proactive versus reactive control strategy in these tasks, we assessed developmental change in the degree to which these two processes were deployed efficiently given the task. Experiment 2 shows that the developmental change observed in Experiment 1 and in Amso et al. (2014) is likely a result of increased efficacy of output gating processes, as well as greater strategic efficiency in that adolescents opt for this costly process less often than children. PMID:27336178

  12. Weighted Radon transforms for which the Chang approximate inversion formula is precise

    CERN Document Server

    Novikov, Roman

    2011-01-01

    We describe all weighted Radon transforms on the plane for which the Chang approximate inversion formula is precise. Some subsequent results, including the Cormack type inversion for these transforms, are also given.

  13. Climatic changes: explicative guide of international agreements

    International Nuclear Information System (INIS)

    The following themes of the negotiation in the United Nations Convention framework, on the climatic changes and the kyoto protocol are taken into account: the observation, the information communication, the policies and the measures, the developing countries, the flexibility mechanisms, the soils utilizations and the regime evolution. For each theme the document recalls quickly how the theme is detailed in the Convention and in the Protocol, it presents then the decisions and the adopted rules and defines the agreements contain, in terms of challenges and implication in the protocol implementation. (A.L.B.)

  14. An ultrasonically levitated noncontact stage using traveling vibrations on precision ceramic guide rails.

    Science.gov (United States)

    Koyama, Daisuke; Ide, Takeshi; Friend, James R; Nakamura, Kentaro; Ueha, Sadayuki

    2007-03-01

    This paper presents a noncontact sliding table design and measurements of its performance via ultrasonic levitation. A slider placed atop two vibrating guide rails is levitated by an acoustic radiation force emitted from the rails. A flexural traveling wave propagating along the guide rails allows noncontact transportation of the slider. Permitting a transport mechanism that reduces abrasion and dust generation with an inexpensive and simple structure. The profile of the sliding table was designed using the finite-element analysis (FEA) for high levitation and transportation efficiency. The prototype sliding table was made of alumina ceramic (Al2O3) to increase machining accuracy and rigidity using a structure composed of a pair of guide rails with a triangular cross section and piezoelectric transducers. Two types of transducers were used: bolt-clamped Langevin transducers and bimorph transducers. A 40-mm long slider was designed to fit atop the two rail guides. Flexural standing waves and torsional standing waves were observed along the guide rails at resonance, and the levitation of the slider was obtained using the flexural mode even while the levitation distance was less than 10 microm. The levitation distance of the slider was measured while increasing the slider's weight. The levitation pressure, rigidity, and vertical displacement amplitude of the levitating slider thus were measured to be 6.7 kN/m2, 3.0 kN/microm/m2, and less than 1 microm, respectively. Noncontact transport of the slider was achieved using phased drive of the two transducers at either end of the vibrating guide rail. By controlling the phase difference, the slider transportation direction could be switched, and a maximum thrust of 13 mN was obtained. PMID:17375828

  15. High-precision robotic microcontact printing (R-μCP) utilizing a vision guided selectively compliant articulated robotic arm.

    Science.gov (United States)

    McNulty, Jason D; Klann, Tyler; Sha, Jin; Salick, Max; Knight, Gavin T; Turng, Lih-Sheng; Ashton, Randolph S

    2014-06-01

    Increased realization of the spatial heterogeneity found within in vivo tissue microenvironments has prompted the desire to engineer similar complexities into in vitro culture substrates. Microcontact printing (μCP) is a versatile technique for engineering such complexities onto cell culture substrates because it permits microscale control of the relative positioning of molecules and cells over large surface areas. However, challenges associated with precisely aligning and superimposing multiple μCP steps severely limits the extent of substrate modification that can be achieved using this method. Thus, we investigated the feasibility of using a vision guided selectively compliant articulated robotic arm (SCARA) for μCP applications. SCARAs are routinely used to perform high precision, repetitive tasks in manufacturing, and even low-end models are capable of achieving microscale precision. Here, we present customization of a SCARA to execute robotic-μCP (R-μCP) onto gold-coated microscope coverslips. The system not only possesses the ability to align multiple polydimethylsiloxane (PDMS) stamps but also has the capability to do so even after the substrates have been removed, reacted to graft polymer brushes, and replaced back into the system. Plus, non-biased computerized analysis shows that the system performs such sequential patterning with <10 μm precision and accuracy, which is equivalent to the repeatability specifications of the employed SCARA model. R-μCP should facilitate the engineering of complex in vivo-like complexities onto culture substrates and their integration with microfluidic devices. PMID:24759945

  16. Development and Evaluation of a Registration Methodology for Information-Guided Precision Robotic Laser Neurosurgery System

    Science.gov (United States)

    Nakamura, Ryoichi; Hara, Mikiko; Omori, Shigeru; Uematsu, Miyuki; Umezu, Mitsuo; Muragaki, Yoshihiro; Iseki, Hiroshi

    To establish safe, precise, and minimally invasive surgery, Computer Aided Surgery (CAS) systems, such as intra-operative imaging and navigation system to detect the location of the target of therapy, and surgical robot system, are very powerful tools. There is strong need to combine these CAS systems for fusion of advanced diagnosis and treatment technologies. In this paper, we introduce our new method to register the intraoperative imaging information, robotic surgery system, and patient using surgical navigation system. Using our Open-MRI navigation system and laser surgery system for neurosurgery, we can make registration between these system and patient precisely. The experimental result shows that the error on the registration between image data and the laser surgery system is low enough to fulfill the requirement of laser surgery system in the use of high-resolution image data. This system realizes the safe, precise and minimally invasive neurosurgery by the combination of intra-operative diagnosis and advanced therapeutic device.

  17. A Guide for Entrepreneurs Who Lead and Manage Change

    Directory of Open Access Journals (Sweden)

    Llynne Plante

    2012-03-01

    Full Text Available To grow a business, entrepreneurs must know how to lead and manage change. However, the change management literature offers little in the way of specific, practical advice that leaders can use to guide their actions. This article builds on a review of the change management literature, a small field study, and years of experience supporting technology companies. It identifies and describes the top nine leadership actions (and their associated behavioural traits that technology entrepreneurs who lead and manage change should carry out.

  18. Spike timing precision changes with spike rate adaptation in the owl's auditory space map.

    Science.gov (United States)

    Keller, Clifford H; Takahashi, Terry T

    2015-10-01

    Spike rate adaptation (SRA) is a continuing change of responsiveness to ongoing stimuli, which is ubiquitous across species and levels of sensory systems. Under SRA, auditory responses to constant stimuli change over time, relaxing toward a long-term rate often over multiple timescales. With more variable stimuli, SRA causes the dependence of spike rate on sound pressure level to shift toward the mean level of recent stimulus history. A model based on subtractive adaptation (Benda J, Hennig RM. J Comput Neurosci 24: 113-136, 2008) shows that changes in spike rate and level dependence are mechanistically linked. Space-specific neurons in the barn owl's midbrain, when recorded under ketamine-diazepam anesthesia, showed these classical characteristics of SRA, while at the same time exhibiting changes in spike timing precision. Abrupt level increases of sinusoidally amplitude-modulated (SAM) noise initially led to spiking at higher rates with lower temporal precision. Spike rate and precision relaxed toward their long-term values with a time course similar to SRA, results that were also replicated by the subtractive model. Stimuli whose amplitude modulations (AMs) were not synchronous across carrier frequency evoked spikes in response to stimulus envelopes of a particular shape, characterized by the spectrotemporal receptive field (STRF). Again, abrupt stimulus level changes initially disrupted the temporal precision of spiking, which then relaxed along with SRA. We suggest that shifts in latency associated with stimulus level changes may differ between carrier frequency bands and underlie decreased spike precision. Thus SRA is manifest not simply as a change in spike rate but also as a change in the temporal precision of spiking. PMID:26269555

  19. A review of treatment planning for precision image-guided photon beam pre-clinical animal radiation studies

    Energy Technology Data Exchange (ETDEWEB)

    Verhaegen, Frank; Hoof, Stefan van; Granton, Patrick V.; Trani, Daniela [Maastricht University Medical Center (Netherlands). Dept. of Radiation Oncology (MAASTRO)

    2014-07-01

    Recently, precision irradiators integrated with a high-resolution CT imaging device became available for pre-clinical studies. These research platforms offer significant advantages over older generations of animal irradiators in terms of precision and accuracy of image-guided radiation targeting. These platforms are expected to play a significant role in defining experiments that will allow translation of research findings to the human clinical setting. In the field of radiotherapy, but also others such as neurology, the platforms create unique opportunities to explore e.g. the synergy between radiation and drugs or other agents. To fully exploit the advantages of this new technology, accurate methods are needed to plan the irradiation and to calculate the three-dimensional radiation dose distribution in the specimen. To this end, dedicated treatment planning systems are needed. In this review we will discuss specific issues for precision irradiation of small animals, we will describe the workflow of animal treatment planning, and we will examine several dose calculation algorithms (factorization, superposition-convolution, Monte Carlo simulation) used for animal irradiation with kilovolt photon beams. Issues such as dose reporting methods, photon scatter, tissue segmentation and motion will also be discussed briefly.

  20. A review of treatment planning for precision image-guided photon beam pre-clinical animal radiation studies

    International Nuclear Information System (INIS)

    Recently, precision irradiators integrated with a high-resolution CT imaging device became available for pre-clinical studies. These research platforms offer significant advantages over older generations of animal irradiators in terms of precision and accuracy of image-guided radiation targeting. These platforms are expected to play a significant role in defining experiments that will allow translation of research findings to the human clinical setting. In the field of radiotherapy, but also others such as neurology, the platforms create unique opportunities to explore e.g. the synergy between radiation and drugs or other agents. To fully exploit the advantages of this new technology, accurate methods are needed to plan the irradiation and to calculate the three-dimensional radiation dose distribution in the specimen. To this end, dedicated treatment planning systems are needed. In this review we will discuss specific issues for precision irradiation of small animals, we will describe the workflow of animal treatment planning, and we will examine several dose calculation algorithms (factorization, superposition-convolution, Monte Carlo simulation) used for animal irradiation with kilovolt photon beams. Issues such as dose reporting methods, photon scatter, tissue segmentation and motion will also be discussed briefly.

  1. A review of treatment planning for precision image-guided photon beam pre-clinical animal radiation studies.

    Science.gov (United States)

    Verhaegen, Frank; van Hoof, Stefan; Granton, Patrick V; Trani, Daniela

    2014-12-01

    Recently, precision irradiators integrated with a high-resolution CT imaging device became available for pre-clinical studies. These research platforms offer significant advantages over older generations of animal irradiators in terms of precision and accuracy of image-guided radiation targeting. These platforms are expected to play a significant role in defining experiments that will allow translation of research findings to the human clinical setting. In the field of radiotherapy, but also others such as neurology, the platforms create unique opportunities to explore e.g. the synergy between radiation and drugs or other agents. To fully exploit the advantages of this new technology, accurate methods are needed to plan the irradiation and to calculate the three-dimensional radiation dose distribution in the specimen. To this end, dedicated treatment planning systems are needed. In this review we will discuss specific issues for precision irradiation of small animals, we will describe the workflow of animal treatment planning, and we will examine several dose calculation algorithms (factorization, superposition-convolution, Monte Carlo simulation) used for animal irradiation with kilovolt photon beams. Issues such as dose reporting methods, photon scatter, tissue segmentation and motion will also be discussed briefly. PMID:24629309

  2. A Guide to Precision Calculations in Dyson's Hierarchical Scalar Field Theory

    CERN Document Server

    Godina, J J; Oktay, M B; Niermann, S M

    1998-01-01

    The goal of this article is to provide a practical method to calculate, in a scalar theory, accurate numerical values of the renormalized quantities which could be used to test any kind of approximate calculation. We use finite truncations of the Fourier transform of the recursion formula for Dyson's hierarchical model in the symmetric phase to perform high-precision calculations of the unsubtracted Green's functions at zero momentum in dimension 3, 4, and 5. We use the well-known correspondence between statistical mechanics and field theory in which the large cut-off limit is obtained by letting beta reach a critical value beta_c (with up to 16 significant digits in our actual calculations). We show that the round-off errors on the magnetic susceptibility grow like (beta_c -beta)^{-1} near criticality. We show that the systematic errors (finite truncations and volume) can be controlled with an exponential precision and reduced to a level lower than the numerical errors. We justify the use of the truncation f...

  3. Guide to precision calculations in Dyson close-quote s hierarchical scalar field theory

    International Nuclear Information System (INIS)

    The goal of this article is to provide a practical method to calculate, in a scalar theory, accurate numerical values of the renormalized quantities which could be used to test any kind of approximate calculation. We use finite truncations of the Fourier transform of the recursion formula for Dyson close-quote s hierarchical model in the symmetric phase to perform high-precision calculations of the unsubtracted Green close-quote s functions at zero momentum in dimension 3, 4, and 5. We use the well-known correspondence between statistical mechanics and field theory in which the large cutoff limit is obtained by letting β reach a critical value βc (with up to 16 significant digits in our actual calculations). We show that the round-off errors on the magnetic susceptibility grow like (βc-β)-1 near criticality. We show that the systematic errors (finite truncations and volume) can be controlled with an exponential precision and reduced to a level lower than the numerical errors. We justify the use of the truncation for calculations of the high-temperature expansion. We calculate the dimensionless renormalized coupling constant corresponding to the 4-point function and show that when β→βc, this quantity tends to a fixed value which can be determined accurately when D=3 (hyperscaling holds), and goes to zero like [Ln(βc-β)]-1 when D=4. copyright 1998 The American Physical Society

  4. Standard guide for precision electroformed wet sieve analysis of nonplastic ceramic powders

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2009-01-01

    1.1 This guide covers the determination of the particle size distribution of pulverized alumina and quartz for particle sizes from 45 to 5 μm by wet sieving. 1.2 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. 1.2.1 The only exception is in the Section 5, Apparatus, 5.1 where there is no relevant SI equivalent. 1.3 This standard does not purport to address the safety concerns associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  5. Precise correlation between MRI and histopathology - Exploring treatment margins for MRI-guided localized breast cancer therapy

    International Nuclear Information System (INIS)

    Background: Magnetic resonance imaging (MRI) is more often considered to guide, evaluate or select patients for partial breast irradiation (PBI) or minimally invasive therapy. Safe treatment margins around the MRI-visible lesion (MRI-GTV) are needed to account for surrounding subclinical occult disease. Purpose: To precisely compare MRI findings with histopathology, and to obtain detailed knowledge about type, rate, quantity and distance of occult disease around the MRI-GTV. Methods and materials: Patients undergoing MRI and breast-conserving therapy were prospectively included. The wide local excision specimens were subjected to detailed microscopic examination. The size of the invasive (index) tumor was compared with the MRI-GTV. The gross tumor volume (GTV) was defined as the pre-treatment visible lesion. Subclinical tumor foci were reconstructed at various distances to the MRI-GTV. Results: Sixty-two patients (64 breasts) were included. The mean size difference between MRI-GTV and the index tumor was 1.3 mm. Subclinical disease occurred in 52% and 25% of the specimens at distances ≥10 mm and ≥20 mm, respectively, from the MRI-GTV. Conclusions: For MRI-guided minimally invasive therapy, typical treatment margins of 10 mm around the MRI-GTV may include occult disease in 52% of patients. When surgery achieves a 10 mm tumor-free margin around the MRI-GTV, radiotherapy to the tumor bed may require clinical target volume margins >10 mm in up to one-fourth of the patients.

  6. Automatic co-registration of space-based sensors for precision change detection and analysis

    Science.gov (United States)

    Bryant, N.; Zobrist, A.; Logan, T.

    2003-01-01

    A variety of techniques were developed at JPL to assure sub-pixel co-registration of scenes and ortho-rectification of satellite imagery to other georeferenced information to permit precise change detection and analysis of low and moderate resolution space sensors.

  7. Automatic prostate localization on cone-beam CT scans for high precision image-guided radiotherapy

    International Nuclear Information System (INIS)

    Purpose: Previously, we developed an automatic three-dimensional gray-value registration (GR) method for fast prostate localization that could be used during online or offline image-guided radiotherapy. The method was tested on conventional computed tomography (CT) scans. In this study, the performance of the algorithm to localize the prostate on cone-beam CT (CBCT) scans acquired on the treatment machine was evaluated. Methods and Materials: Five to 17 CBCT scans of 32 prostate cancer patients (332 scans in total) were used. For 18 patients (190 CBCT scans), the CBCT scans were acquired with a collimated field of view (FOV) (craniocaudal). This procedure improved the image quality considerably. The prostate (i.e., prostate plus seminal vesicles) in each CBCT scan was registered to the prostate in the planning CT scan by automatic 3D gray-value registration (normal GR) starting from a registration on the bony anatomy. When these failed, registrations were repeated with a fixed rotation point locked at the prostate apex (fixed apex GR). Registrations were visually assessed in 3D by one observer with the help of an expansion (by 3.6 mm) of the delineated prostate contours of the planning CT scan. The percentage of successfully registered cases was determined from the combined normal and fixed apex GR assessment results. The error in gray-value registration for both registration methods was determined from the position of one clearly defined calcification in the prostate gland (9 patients, 71 successful registrations). Results: The percentage of successfully registered CBCT scans that were acquired with a collimated FOV was about 10% higher than for CBCT scans that were acquired with an uncollimated FOV. For CBCT scans that were acquired with a collimated FOV, the percentage of successfully registered cases improved from 65%, when only normal GR was applied, to 83% when the results of normal and fixed apex GR were combined. Gray-value registration mainly failed (or

  8. Changing paradigm of cancer therapy: precision medicine by next-generation sequencing

    Science.gov (United States)

    Xue, Yuan; Wilcox, William R.

    2016-01-01

    Precision medicine aims to identify the right drug, for the right patient, at the right dose, at the right time, which is particularly important in cancer therapy. Problems such as the variability of treatment response and resistance to medication have been long-standing challenges in oncology, especially for development of new medications. Solid tumors, unlike hematologic malignancies or brain tumors, are remarkably diverse in their cellular origins and developmental timing. The ability of next-generation sequencing (NGS) to analyze the comprehensive landscape of genetic alterations brings promises to diseases that have a highly complex and heterogeneous genetic composition such as cancer. Here we provide an overview of how NGS is able to facilitate precision medicine and change the paradigm of cancer therapy, especially for solid tumors, through technical advancements, molecular diagnosis, response monitoring and clinical trials. PMID:27144059

  9. Changing paradigm of cancer therapy:precision medicine by next-generation sequencing

    Institute of Scientific and Technical Information of China (English)

    Yuan Xue; William R Wilcox

    2016-01-01

    Precision medicine aims to identify the right drug, for the right patient, at the right dose, at the right time, which is particularly important in cancer therapy. Problems such as the variability of treatment response and resistance to medication have been long-standing challenges in oncology, especially for development of new medications. Solid tumors, unlike hematologic malignancies or brain tumors, are remarkably diverse in their cellular origins and developmental timing. The ability of next-generation sequencing (NGS) to analyze the comprehensive landscape of genetic alterations brings promises to diseases that have a highly complex and heterogeneous genetic composition such as cancer. Here we provide an overview of how NGS is able to facilitate precision medicine and change the paradigm of cancer therapy, especially for solid tumors, through technical advancements, molecular diagnosis, response monitoring and clinical trials.

  10. Guiding climate change adaptation within vulnerable natural resource management systems.

    Science.gov (United States)

    Bardsley, Douglas K; Sweeney, Susan M

    2010-05-01

    Climate change has the potential to compromise the sustainability of natural resources in Mediterranean climatic systems, such that short-term reactive responses will increasingly be insufficient to ensure effective management. There is a simultaneous need for both the clear articulation of the vulnerabilities of specific management systems to climate risk, and the development of appropriate short- and long-term strategic planning responses that anticipate environmental change or allow for sustainable adaptive management in response to trends in resource condition. Governments are developing climate change adaptation policy frameworks, but without the recognition of the importance of responding strategically, regional stakeholders will struggle to manage future climate risk. In a partnership between the South Australian Government, the Adelaide and Mt Lofty Ranges Natural Resource Management Board and the regional community, a range of available research approaches to support regional climate change adaptation decision-making, were applied and critically examined, including: scenario modelling; applied and participatory Geographical Information Systems modelling; environmental risk analysis; and participatory action learning. As managers apply ideas for adaptation within their own biophysical and socio-cultural contexts, there would be both successes and failures, but a learning orientation to societal change will enable improvements over time. A base-line target for regional responses to climate change is the ownership of the issue by stakeholders, which leads to an acceptance that effective actions to adapt are now both possible and vitally important. Beyond such baseline knowledge, the research suggests that there is a range of tools from the social and physical sciences available to guide adaptation decision-making. PMID:20383706

  11. Guiding Climate Change Adaptation Within Vulnerable Natural Resource Management Systems

    Science.gov (United States)

    Bardsley, Douglas K.; Sweeney, Susan M.

    2010-05-01

    Climate change has the potential to compromise the sustainability of natural resources in Mediterranean climatic systems, such that short-term reactive responses will increasingly be insufficient to ensure effective management. There is a simultaneous need for both the clear articulation of the vulnerabilities of specific management systems to climate risk, and the development of appropriate short- and long-term strategic planning responses that anticipate environmental change or allow for sustainable adaptive management in response to trends in resource condition. Governments are developing climate change adaptation policy frameworks, but without the recognition of the importance of responding strategically, regional stakeholders will struggle to manage future climate risk. In a partnership between the South Australian Government, the Adelaide and Mt Lofty Ranges Natural Resource Management Board and the regional community, a range of available research approaches to support regional climate change adaptation decision-making, were applied and critically examined, including: scenario modelling; applied and participatory Geographical Information Systems modelling; environmental risk analysis; and participatory action learning. As managers apply ideas for adaptation within their own biophysical and socio-cultural contexts, there would be both successes and failures, but a learning orientation to societal change will enable improvements over time. A base-line target for regional responses to climate change is the ownership of the issue by stakeholders, which leads to an acceptance that effective actions to adapt are now both possible and vitally important. Beyond such baseline knowledge, the research suggests that there is a range of tools from the social and physical sciences available to guide adaptation decision-making.

  12. 精密模具中粘接型导套的应用%Application of the Bonding-Typed Guide Bushes in Precision Dies

    Institute of Scientific and Technical Information of China (English)

    吴水勇

    2001-01-01

    模具加工过程中,固定导套通常采用的工艺是通过过盈配合将导套压入导套固定板的方法,即压入法。但此方法用于精密模具 (如电机定转子叠铆模 )则有一定的弊端,用胶水粘接导套的方法可适用于精密模具。%In the processing of dies, the technological process usually adopted for matching the guide bushes is the overfilling method, namely the pressing- in method. But it is not suit for precision dies, such as the folding and riveting die for the stators and rotators of motors. For precision dies, the method of bonding the guide bushes with glue is applicable.

  13. A Big Data Guide to Understanding Climate Change: The Case for Theory-Guided Data Science.

    Science.gov (United States)

    Faghmous, James H; Kumar, Vipin

    2014-09-01

    Global climate change and its impact on human life has become one of our era's greatest challenges. Despite the urgency, data science has had little impact on furthering our understanding of our planet in spite of the abundance of climate data. This is a stark contrast from other fields such as advertising or electronic commerce where big data has been a great success story. This discrepancy stems from the complex nature of climate data as well as the scientific questions climate science brings forth. This article introduces a data science audience to the challenges and opportunities to mine large climate datasets, with an emphasis on the nuanced difference between mining climate data and traditional big data approaches. We focus on data, methods, and application challenges that must be addressed in order for big data to fulfill their promise with regard to climate science applications. More importantly, we highlight research showing that solely relying on traditional big data techniques results in dubious findings, and we instead propose a theory-guided data science paradigm that uses scientific theory to constrain both the big data techniques as well as the results-interpretation process to extract accurate insight from large climate data. PMID:25276499

  14. Transitions: A Guide to Teens Getting Older and Changing Health Care Providers

    Science.gov (United States)

    ... Sexual Health Medical Conditions Nutrition & Fitness Emotional Health Transitions: A Guide to Getting Older and Changing Health ... pediatrician for most of your life. What are transitions? Transitions are times when changes in your life ...

  15. Image-guided radiation therapy. Paradigm change in radiation therapy; Bildgestuetzte Strahlentherapie. Paradigmenwechsel in der Strahlentherapie

    Energy Technology Data Exchange (ETDEWEB)

    Wenz, F. [Universitaetsmedizin Mannheim der Universitaet Heidelberg, Klinik fuer Strahlentherapie und Radioonkologie, Mannheim (Germany); Belka, C. [Klinikum der Ludwig-Maximilians-Universitaet, Klinik fuer Strahlentherapie und Radioonkologie, Muenchen (Germany); Reiser, M. [Klinikum der Ludwig-Maximilians-Universitaet, Institut fuer Klinische Radiologie, Muenchen (Germany); Schoenberg, S.O. [Universitaetsmedizin Mannheim der Universitaet Heidelberg, Institut fuer Klinische Radiologie und Nuklearmedizin, Mannheim (Germany)

    2012-03-15

    The introduction of image-guided radiotherapy (IGRT) has changed the workflow in radiation oncology more dramatically than any other innovation in the last decades. Imaging for treatment planning before the initiation of the radiotherapy series does not take alterations in patient anatomy and organ movement into account. The principle of IGRT is the temporal and spatial connection of imaging in the treatment position immediately before radiation treatment. The actual position and the target position are compared using cone-beam computed tomography (CT) or stereotactic ultrasound. The IGRT procedure allows a reduction of the safety margins and dose to normal tissue without an increase in risk of local recurrence. In the future the linear treatment chain in radiation oncology will be developed based on the closed-loop feedback principle. The IGRT procedure is increasingly being used especially for high precision radiotherapy, e.g. for prostate or brain tumors. (orig.) [German] Die Einfuehrung der bildgestuetzten Radiotherapie (IGRT - ''image-guided radiotherapy'') hat wie kaum eine andere Innovation die Behandlungsablaeufe in der Radioonkologie veraendert. Eine einmalige Bildgebung zur Bestrahlungsplanung vor der Behandlungsserie beruecksichtigt nicht die Aenderung der Patientengeometrie und die Organbeweglichkeit. Das Prinzip der IGRT besteht in der raeumlichen und zeitlichen Zusammenfuehrung von Bildgebung in der Bestrahlungsposition unmittelbar vor der eigentlichen Bestrahlung. Mittels Cone-beam-CT oder stereotaktischem Ultraschall wird die Ist- mit der Sollposition verglichen. Die IGRT erlaubt die Reduktion der Sicherheitssaeume und damit die Schonung des Normalgewebes, ohne das Rezidivrisiko zu erhoehen. Zukuenftig wird die lineare Behandlungskette in der Radioonkologie durch eine geschlossene, multipel rueckgekoppelte Therapieschleife ersetzt werden. Speziell bei Praezisionsbestrahlungen wie z. B. Prostata- oder Hirntumoren kommt die IGRT

  16. Guided-wave second harmonics in Nd:YCOB ridge waveguides produced by combination of carbon ion irradiation and precise diamond blade dicing

    Science.gov (United States)

    Li, Rang; Nie, Weijie; Shang, Zhen; Cheng, Chen; Akhmadaliev, Shavkat; Zhou, Shengqiang; Lu, Qingming; Chen, Feng

    2016-07-01

    We report on the fabrication of Nd:YCa4O(BO3)3 (Nd:YCOB) ridge waveguides by combining carbon ion irradiation and precise diamond blade dicing. The guiding and spectroscopic properties of the planar as well as ridge waveguides are investigated. The second harmonic generation (SHG) at 532 nm has been realized through the waveguide structures. With nearly the same input power, the maximum average output powers are 0.56 mW and 0.62 mW, and the maximum conversion efficiencies reach 0.3%W-1 and 0.5%W-1, for planar and ridge waveguides, respectively.

  17. Structural Integrity Evaluation of Cold Neutron Laboratory Building by Design Change of Guide Shielding Room

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Sangik; Kim, Youngki; Kim, Harkrho

    2007-06-15

    This report summarizes the results of the structural integrity evaluation for the cold neutron laboratory building by design change of guide shielding room. The design of the guide shielding room was changed by making its structure members in normal concrete (2.3 g/cc) instead of heavy concrete (3.5 g/cc) because the heavy concrete could be not supplied to meet its design specification. Therefore, it was decided that the guide shielding room is made of the normal concrete. And, the shielding performance of the normal concrete was recalculated to confirm satisfying its design specification, which is of a 9000 zone according to HANARO radiation region classification. The change makes the shielding wall thicker than existing design, and then it is caused to qualify the structural integrity evaluation of the CNLB. Finally, the structural integrity of the CNLB was re-evaluated by considering the design change of the guide shielding room.

  18. 77 FR 52741 - Compliance Policy Guide Sec. 420.300 Changes in Compendial Specifications and New Drug...

    Science.gov (United States)

    2012-08-30

    ... HUMAN SERVICES Food and Drug Administration Compliance Policy Guide Sec. 420.300 Changes in Compendial... withdrawal of Compliance Policy Guide (CPG) Sec. 420.300 Changes in Compendial Specifications and New Drug Application (NDA) Supplements. CPG Sec. 420.300 is included in FDA's Compliance Policy Guides Manual...

  19. Precision required for dose-escalated treatment of spinal metastases and implications for image-guided radiation therapy (IGRT)

    International Nuclear Information System (INIS)

    Introduction: To evaluate the precision required in dose-escalated IMRT treatment of spinal metastases and paraspinal tumors. Methods: In IMRT treatment plans of nine patients with spinal metastases (n = 7) and paraspinal tumors (n = 2) translational patient positioning errors (0-10 mm) and rotational errors (0-7.5 deg.) were simulated. The dose to the spinal cord (D5spine) resulting from these simulations was evaluated and NTCP for spinal cord necrosis was calculated. All patient set-up errors observed during treatment were simulated and the influence on D5spine was investigated. Results: To keep the dose distribution to the spinal cord within ±5% (±10%) of the prescribed dose, maximum tolerable errors of 1 mm (2 mm) in the transversal plane, 4 mm (7 mm) in superior-inferior direction and maximum rotations of 3.5 deg. (5 deg.) were calculated on average. The translational and rotational component of clinically observed set-up errors increased D5spine by 23 ± 14% and 3 ± 2% on average, respectively. Conclusion: Steep dose gradients of IMRT planning require very high precision. In selected patients correction of both translational and rotational errors may be beneficial

  20. The Deep Change Field Guide A Personal Course to Discovering the Leader Within

    CERN Document Server

    Quinn, Robert E

    2012-01-01

    How to realize your own leadership potential Based on the bestselling book, Deep Change, The Deep Change Field Guide takes readers through the introspective journey of personal transformation. The field guide streamlines, updates, and augments the content of the original book into an interactive self-teaching course that helps readers learn how to become powerful agents of change. Learning tools include reflection questions, film assignments, and action plans that help readers think about the concepts in terms of their own situations, and identify actions to embody the concepts in their lives.

  1. Evaluation of the precision of portal-image-guided head-and-neck localization: An intra- and interobserver study

    International Nuclear Information System (INIS)

    There is increasing evidence that, for some patients, image-guided intensity-modulated radiation therapy (IMRT) for head-and-neck cancer patients may maintain target dose coverage and critical organ (e.g., parotids) dose closer to the planned doses than setup using lasers alone. We investigated inter- and intraobserver uncertainties in patient setup in head-and-neck cancer patients. Twenty-two sets of orthogonal digital portal images (from five patients) were selected from images used for daily localization of head-and-neck patients treated with IMRT. To evaluate interobserver variations, five radiation therapists compared the portal images with the plan digitally reconstructed radiographs and reported shifts for the isocenter (∼C2) and for a supraclavicular reference point. One therapist repeated the procedure a month later to evaluate intraobserver variations. The procedure was then repeated with teams of two therapists. The frequencies for which agreement between the shift reported by the observer and the daily mean shift (average of all observers for a given image set) were less than 1.5 and 2.5 mm were calculated. Standard errors of measurement for the intra- and interobserver uncertainty (SEMintra and SEMinter) for the individual and teams were calculated. The data showed that there was very little difference between individual therapists and teams. At isocenter, 80%-90% of all reported shifts agreed with the daily average within 1.5 mm, showing consistency in the ways both individuals and teams interpret the images (SEMinter∼1 mm). This dropped to 65% for the supraclavicular point (SEMinter∼1.5 mm). Uncertainties increased for larger setup errors. In conclusion, image-guided patient positioning allows head-and-neck patients to be controlled within 3-4 mm. This is similar to the setup uncertainties found for most head-and-neck patients, but may provide some improvement for the subset of patients with larger setup uncertainties

  2. Secondary Agricultural Education Teachers as Agents of Change in Oklahoma and the Adoption of Precision Agriculture

    Science.gov (United States)

    Nickeson, Beth

    2013-01-01

    Research indicates that precision agricultural education (PAE) in Oklahoma affects environmental quality, water conservation, and crop yields. The purpose of this mixed methods study was to explore the nature and perceived effectiveness of PAE in Oklahoma secondary agricultural education classes. The study was framed by the diffusion of…

  3. Strategies for Change: A Field Guide to Social Marketing for School Health Professionals

    Science.gov (United States)

    American School Health Association (NJ3), 2004

    2004-01-01

    Strategies for Change outlines how to use social marketing strategies to influence change in the health programs in a building, district or community. Authors describe how to develop a strategy to influence district administrators, school board members, colleagues and parents. This step-by-step guide leads through the process for developing,…

  4. Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalised Nutrition: Part 1 - Fields of Precision Nutrition.

    Science.gov (United States)

    Ferguson, Lynnette R; De Caterina, Raffaele; Görman, Ulf; Allayee, Hooman; Kohlmeier, Martin; Prasad, Chandan; Choi, Myung Sook; Curi, Rui; de Luis, Daniel Antonio; Gil, Ángel; Kang, Jing X; Martin, Ron L; Milagro, Fermin I; Nicoletti, Carolina Ferreira; Nonino, Carla Barbosa; Ordovas, Jose Maria; Parslow, Virginia R; Portillo, María P; Santos, José Luis; Serhan, Charles N; Simopoulos, Artemis P; Velázquez-Arellano, Antonio; Zulet, Maria Angeles; Martinez, J Alfredo

    2016-01-01

    Diversity in the genetic profile between individuals and specific ethnic groups affects nutrient requirements, metabolism and response to nutritional and dietary interventions. Indeed, individuals respond differently to lifestyle interventions (diet, physical activity, smoking, etc.). The sequencing of the human genome and subsequent increased knowledge regarding human genetic variation is contributing to the emergence of personalized nutrition. These advances in genetic science are raising numerous questions regarding the mode that precision nutrition can contribute solutions to emerging problems in public health, by reducing the risk and prevalence of nutrition-related diseases. Current views on personalized nutrition encompass omics technologies (nutrigenomics, transcriptomics, epigenomics, foodomics, metabolomics, metagenomics, etc.), functional food development and challenges related to legal and ethical aspects, application in clinical practice, and population scope, in terms of guidelines and epidemiological factors. In this context, precision nutrition can be considered as occurring at three levels: (1) conventional nutrition based on general guidelines for population groups by age, gender and social determinants; (2) individualized nutrition that adds phenotypic information about the person's current nutritional status (e.g. anthropometry, biochemical and metabolic analysis, physical activity, among others), and (3) genotype-directed nutrition based on rare or common gene variation. Research and appropriate translation into medical practice and dietary recommendations must be based on a solid foundation of knowledge derived from studies on nutrigenetics and nutrigenomics. A scientific society, such as the International Society of Nutrigenetics/Nutrigenomics (ISNN), internationally devoted to the study of nutrigenetics/nutrigenomics, can indeed serve the commendable roles of (1) promoting science and favoring scientific communication and (2) permanently

  5. Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine.

    Science.gov (United States)

    Van Allen, Eliezer M; Wagle, Nikhil; Stojanov, Petar; Perrin, Danielle L; Cibulskis, Kristian; Marlow, Sara; Jane-Valbuena, Judit; Friedrich, Dennis C; Kryukov, Gregory; Carter, Scott L; McKenna, Aaron; Sivachenko, Andrey; Rosenberg, Mara; Kiezun, Adam; Voet, Douglas; Lawrence, Michael; Lichtenstein, Lee T; Gentry, Jeff G; Huang, Franklin W; Fostel, Jennifer; Farlow, Deborah; Barbie, David; Gandhi, Leena; Lander, Eric S; Gray, Stacy W; Joffe, Steven; Janne, Pasi; Garber, Judy; MacConaill, Laura; Lindeman, Neal; Rollins, Barrett; Kantoff, Philip; Fisher, Sheila A; Gabriel, Stacey; Getz, Gad; Garraway, Levi A

    2014-06-01

    Translating whole-exome sequencing (WES) for prospective clinical use may have an impact on the care of patients with cancer; however, multiple innovations are necessary for clinical implementation. These include rapid and robust WES of DNA derived from formalin-fixed, paraffin-embedded tumor tissue, analytical output similar to data from frozen samples and clinical interpretation of WES data for prospective use. Here, we describe a prospective clinical WES platform for archival formalin-fixed, paraffin-embedded tumor samples. The platform employs computational methods for effective clinical analysis and interpretation of WES data. When applied retrospectively to 511 exomes, the interpretative framework revealed a 'long tail' of somatic alterations in clinically important genes. Prospective application of this approach identified clinically relevant alterations in 15 out of 16 patients. In one patient, previously undetected findings guided clinical trial enrollment, leading to an objective clinical response. Overall, this methodology may inform the widespread implementation of precision cancer medicine. PMID:24836576

  6. Weathering climate change. Some simple rules to guide adaptation decisions

    International Nuclear Information System (INIS)

    This paper discusses some of the elements that may characterise an efficient strategy to adapt to a changing climate. Such a strategy will have to reflect the long time horizon of, and the prevailing uncertainties about, climate change. An intuitively appealing approach therefore seems to be to enhance the flexibility and resilience of systems to react to and cope with climate shocks and extremes, as well as to improve information. In addition, in the case of quasi-irreversible investments with a long lifetime (e.g. infrastructure investments, development of coastal zones), precautionary adjustments may be called for to increase the robustness of structures, or to increase the rate of depreciation to allow for earlier replacement. Many of these measures may already have to be considered now, and could be worthwhile in their own right, independent of climate change considerations

  7. The climate crisis: An introductory guide to climate change

    Science.gov (United States)

    Trenberth, Kevin E.

    2011-06-01

    Human-induced climate change, sometimes called “global warming,” has, unfortunately, become a “hot” topic, embroiled in controversy, misinformation, and claims and counterclaims. It should not be this way, because there are many scientific facts that provide solid information on which to base policy. There is a very strong observational, theoretical, and modeling base in physical science that underpins current understanding of what has happened to Earth's climate and why and what the prospects are for the future under certain assumptions. Moreover, these changes have impacts, which are apt to grow, on the environment and human society. To avoid or reduce these impacts and the economic and human effects of undesirable future climate change requires actions that are strongly opposed by those with vested interests in the status quo, some of whom have funded misinformation campaigns that have successfully confused the public and some politicians, leading to paralysis in political action. Without mitigation of climate change, one would suppose that at least society would plan sensibly for the changes already happening and projected, but such future adaptation plans are also largely in limbo. The implication is that we will suffer the consequences. All of these aspects are addressed in this informative and attractive book, which is written for a fairly general but technically informed audience. The book is strongly based upon the 2007 Fourth Assessment Report (AR4) of the Intergovernmental Panel on Climate Change (IPCC) and therefore has a solid scientific basis. Many figures, graphs, and maps come from the three IPCC working group reports, although the captions often do not explain the detail shown. Given that the IPCC reports totaled nearly 3000 pages, to distill the complex material down to 249 pages is no mean task, and the authors have succeeded quite well.

  8. Understanding Cervical Changes: A Health Guide for Women

    Science.gov (United States)

    ... Types Bladder Cancer Breast Cancer Colorectal Cancer Kidney (Renal Cell) Cancer Leukemia Lung Cancer Lymphoma Pancreatic Cancer ... don't look completely normal, but it's not clear if the changes are caused by HPV infection. Other ... cell carcinoma or adenocarcinoma ) are found. However, for women who ...

  9. Avoiding maladaptation to climate change: towards guiding principles

    International Nuclear Information System (INIS)

    The recent publication of the Physical Science Basis volume of IPCC's Fifth Assessment Report reaffirms an already known conclusion: even drastic reductions of global greenhouse gas emissions will be insufficient to avoid some of the impacts of climate change, and is becoming increasingly clear that the temperature increase by the end of the century is likely to exceed the official target of +2 deg. C. Urgent efforts are thus more than ever needed to support socio-ecological systems threatened by climate change, but how to make adaptation happen on the ground remains vague. Consequently, there is a real risk that climate funding may support initiatives that are actually harmful for the socio-ecological systems, i.e. that foster adaptation in the short-term but insidiously affect systems' long-term vulnerability and/or adaptive capacity to climate change. This generally defines 'mal-adaptation', and this paper affirms that avoiding mal-adaptation is a first key concrete step towards adaptation in a broader sense. Focusing on coastal areas at a local scale and with the aim of providing insights to help avoiding mal-adaptation to climate change on the ground, this paper develops eleven practice-oriented guidelines that address the environmental, socio-cultural and economic dimensions of adaptation initiatives (policies, plans, projects). Based upon this, it affirms that the more guidelines an initiative addresses, the lower will be the risk of mal-adaptation. Together, these guidelines and this assumption constitute the 'Assessment framework' for approaching mal-adaptation to climate change at a local level. (author)

  10. Forecasting hypoxia in the Chesapeake Bay and Gulf of Mexico: model accuracy, precision, and sensitivity to ecosystem change

    International Nuclear Information System (INIS)

    Increasing use of ecological models for management and policy requires robust evaluation of model precision, accuracy, and sensitivity to ecosystem change. We conducted such an evaluation of hypoxia models for the northern Gulf of Mexico and Chesapeake Bay using hindcasts of historical data, comparing several approaches to model calibration. For both systems we find that model sensitivity and precision can be optimized and model accuracy maintained within reasonable bounds by calibrating the model to relatively short, recent 3 year datasets. Model accuracy was higher for Chesapeake Bay than for the Gulf of Mexico, potentially indicating the greater importance of unmodeled processes in the latter system. Retrospective analyses demonstrate both directional and variable changes in sensitivity of hypoxia to nutrient loads.

  11. A Big Data Guide to Understanding Climate Change: The Case for Theory-Guided Data Science

    OpenAIRE

    Faghmous, James H.; Kumar, Vipin

    2014-01-01

    Global climate change and its impact on human life has become one of our era's greatest challenges. Despite the urgency, data science has had little impact on furthering our understanding of our planet in spite of the abundance of climate data. This is a stark contrast from other fields such as advertising or electronic commerce where big data has been a great success story. This discrepancy stems from the complex nature of climate data as well as the scientific questions climate science brin...

  12. Guiding Science and Policy Through the Global Climate Change Debate

    Science.gov (United States)

    Silson, J.; Bullock, M. A.; Frodeman, R. L.

    2001-12-01

    Facing the possibility of global climate change, policy makers are forced to make decisions about the research and application of science and technology to mitigate both the causes and effects of an evolving global climate. In the past, when deciding what kinds of research to fund, policy makers have relied on the criteria of feasibility and possible effectiveness in choosing areas to support. However, given both the complexity of the climate and its sensitivity to human decisions, future policy makers will need to develop a variety of criteria for choosing which subjects are worth pursuing. One issue that policy makers are likely to consider is the restriction of some areas of research based on the possible dangers that they may entail. This talk considers the question of whether and how policy makers should make such decisions within the context of global climate change.

  13. Climatic changes: explicative guide of international agreements; Changements climatiques: guide explicatif des accords internationaux

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    The following themes of the negotiation in the United Nations Convention framework, on the climatic changes and the kyoto protocol are taken into account: the observation, the information communication, the policies and the measures, the developing countries, the flexibility mechanisms, the soils utilizations and the regime evolution. For each theme the document recalls quickly how the theme is detailed in the Convention and in the Protocol, it presents then the decisions and the adopted rules and defines the agreements contain, in terms of challenges and implication in the protocol implementation. (A.L.B.)

  14. Changing Minds A Guide to Facilitated Participatory Planning

    CERN Document Server

    Dodge, Cole P

    2011-01-01

    This book draws on the work of thinkers and doers throughout the world who have grappled with the challenge of planning complex institutions, especially health systems and development projects. Their problem: Conventional planning methods often do not work. The solution: Involve all the key stakeholders in making the plan. The challenge: Devise a planning system that the principals and stakeholders can trust, and that is inclusive, balanced, and dynamic. Facilitated participatory planning (or FPP) is a new way of planning for a world that is complex, competitive, and fast-changing; a world whe

  15. Strategic planning and action on climate change: A guide for Canadian mining companies

    International Nuclear Information System (INIS)

    This Guide has been developed by the Pembina Institute for Appropriate Development of Drayton Valley, Alberta and Stratos Inc., of Ottawa, as a project for the Mining Association of Canada, in an effort to assist senior executives in the Canadian mining industry in developing corporate strategic responses to the risks and opportunities associated with climate change and sustainable development. Section One of the Guide provides an introduction to the scientific, political and legal issues involved in climate change. Section Two outlines the implications of this issue for Canadian mining companies. Section Three and Four provide senior managers with a strategic framework to help understand the scope of a comprehensive response and assist them in developing and integrating climate change policies into their overall corporate strategy and business plan. Section Five outlines the major components of a generic climate change strategy and action plan, while Section Six looks at specific technical opportunity areas where mining companies can reduce greenhouse gas emissions. Section Seven focuses on business opportunities related to greenhouse gas emission reductions that can be implemented domestically or internationally outside of Canadian mining operations. Section Eight concludes the Guide with a comprehensive list of references and additional sources of information to assist users in follow-up and implementation. The accompanying companion handbook, entitled 'Guide to inventorying, measuring and reporting on climate change actions for MAC member companies' is designed to be used by energy managers and technical support staff who are responsible for implementing greenhouse gas measurement reporting systems. In addition to the Guide, the Mining Association and the Pembina Institute also developed three versions of a climate change strategy workshop designed for mining company personnel at different levels and different responsibilities. These workshops can also be

  16. A Conceptual and Measurement Framework to Guide Policy Development and Systems Change

    Science.gov (United States)

    Schalock, Robert L.; Verdugo, Miguel Angel

    2012-01-01

    The authors describe a conceptual and measurement framework that provides a template for guiding policy development and systems change. The framework is built on the concepts of vertical and horizontal alignment, system-level processes, and organization-level practices. Application of the framework can structure the thinking and analytic…

  17. Changing values, changing communities: A guide to the development of healthy, sustainable communities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This guide examines four alternative planning approaches which have emerged in response to concerns about the livability and sustainability of communities: Neo-traditional planning, the pedestrian pocket, cohousing, and the eco-village concept. The guide is intended to aid in evaluating these and other approaches in terms of how they contribute to the development of healthy, sustainable communities. It provides an evaluative framework which defines the essential attributes of a healthy, sustainable community, identifies related planning goals, and identifies some of the tools which communities may use to meet their goals. The guide also presents eight case studies which exemplify the four approaches and reviews these studies to illustrate how the evaluative framework may be applied. The case studies are from British Columbia, Oregon, Alberta, and Ontario, and range in size from a 17-unit housing project to a community for 27,000 people.

  18. Precise automatic image coregistration tools to enable pixel-level change detection Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Automated detection of land cover changes between multitemporal images has long been a goal of the remote sensing discipline. Most research in this area has focused...

  19. Precise Automatic Image Coregistration Tools to Enable Pixel-Level Change Detection Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Automated detection of land cover changes between multitemporal images (i.e., images captured at different times) has long been a goal of the remote sensing...

  20. Applications of Optical Interferometer Techniques for Precision Measurements of Changes in Temperature, Growth and Refractive Index of Materials

    Directory of Open Access Journals (Sweden)

    Rami Reddy Bommareddi

    2014-05-01

    Full Text Available Optical metrology techniques used to measure changes in thickness; temperature and refractive index are surveyed. Optical heterodyne detection principle and its applications for precision measurements of changes in thickness and temperature are discussed. Theoretical formulations are developed to estimate crystal growth rate, surface roughness and laser cooling/heating of solids. Applications of Michelson and Mach-Zehnder interferometers to measure temperature changes in laser heating of solids are described. A Mach-Zehnder interferometer is used to measure refractive index and concentration variations of solutions in crystal growth experiments. Additionally, fluorescence lifetime sensing and fluorescence ratio method are described for temperature measurement. For all the above techniques, uncertainty calculations are included.

  1. SU-E-J-03: Characterization of the Precision and Accuracy of a New, Preclinical, MRI-Guided Focused Ultrasound System for Image-Guided Interventions in Small-Bore, High-Field Magnets

    Energy Technology Data Exchange (ETDEWEB)

    Ellens, N [Johns Hopkins University, Baltimore, Maryland (United States); Farahani, K [National Cancer Institute, Bethesda, MD (United States)

    2015-06-15

    Purpose: MRI-guided focused ultrasound (MRgFUS) has many potential and realized applications including controlled heating and localized drug delivery. The development of many of these applications requires extensive preclinical work, much of it in small animal models. The goal of this study is to characterize the spatial targeting accuracy and reproducibility of a preclinical high field MRgFUS system for thermal ablation and drug delivery applications. Methods: The RK300 (FUS Instruments, Toronto, Canada) is a motorized, 2-axis FUS positioning system suitable for small bore (72 mm), high-field MRI systems. The accuracy of the system was assessed in three ways. First, the precision of the system was assessed by sonicating regular grids of 5 mm squares on polystyrene plates and comparing the resulting focal dimples to the intended pattern, thereby assessing the reproducibility and precision of the motion control alone. Second, the targeting accuracy was assessed by imaging a polystyrene plate with randomly drilled holes and replicating the hole pattern by sonicating the observed hole locations on intact polystyrene plates and comparing the results. Third, the practicallyrealizable accuracy and precision were assessed by comparing the locations of transcranial, FUS-induced blood-brain-barrier disruption (BBBD) (observed through Gadolinium enhancement) to the intended targets in a retrospective analysis of animals sonicated for other experiments. Results: The evenly-spaced grids indicated that the precision was 0.11 +/− 0.05 mm. When image-guidance was included by targeting random locations, the accuracy was 0.5 +/− 0.2 mm. The effective accuracy in the four rodent brains assessed was 0.8 +/− 0.6 mm. In all cases, the error appeared normally distributed (p<0.05) in both orthogonal axes, though the left/right error was systematically greater than the superior/inferior error. Conclusions: The targeting accuracy of this device is sub-millimeter, suitable for many

  2. SU-E-J-03: Characterization of the Precision and Accuracy of a New, Preclinical, MRI-Guided Focused Ultrasound System for Image-Guided Interventions in Small-Bore, High-Field Magnets

    International Nuclear Information System (INIS)

    Purpose: MRI-guided focused ultrasound (MRgFUS) has many potential and realized applications including controlled heating and localized drug delivery. The development of many of these applications requires extensive preclinical work, much of it in small animal models. The goal of this study is to characterize the spatial targeting accuracy and reproducibility of a preclinical high field MRgFUS system for thermal ablation and drug delivery applications. Methods: The RK300 (FUS Instruments, Toronto, Canada) is a motorized, 2-axis FUS positioning system suitable for small bore (72 mm), high-field MRI systems. The accuracy of the system was assessed in three ways. First, the precision of the system was assessed by sonicating regular grids of 5 mm squares on polystyrene plates and comparing the resulting focal dimples to the intended pattern, thereby assessing the reproducibility and precision of the motion control alone. Second, the targeting accuracy was assessed by imaging a polystyrene plate with randomly drilled holes and replicating the hole pattern by sonicating the observed hole locations on intact polystyrene plates and comparing the results. Third, the practicallyrealizable accuracy and precision were assessed by comparing the locations of transcranial, FUS-induced blood-brain-barrier disruption (BBBD) (observed through Gadolinium enhancement) to the intended targets in a retrospective analysis of animals sonicated for other experiments. Results: The evenly-spaced grids indicated that the precision was 0.11 +/− 0.05 mm. When image-guidance was included by targeting random locations, the accuracy was 0.5 +/− 0.2 mm. The effective accuracy in the four rodent brains assessed was 0.8 +/− 0.6 mm. In all cases, the error appeared normally distributed (p<0.05) in both orthogonal axes, though the left/right error was systematically greater than the superior/inferior error. Conclusions: The targeting accuracy of this device is sub-millimeter, suitable for many

  3. The heart of the matter: from guided microtools to 3-D printing and precision genome editing, promising research could lead to new advances in pediatric cardiology.

    Science.gov (United States)

    Chandler, David L

    2015-01-01

    The smooth, powerful muscles of a newborn baby?s heart are pulsing normally, squeezing in and letting go rhythmically as a 3-mm-wide catheter-like tube snakes its way through, entering via an artery and being guided slowly by a surgeon. When it reaches its target?a protruding knot of malformed muscle tissue within a ventricle that has been partly blocking the valve?the tip of the precisely controlled tube whirs into action, with tiny scissor-like rotating blades gently grinding up the excess tissue as those pieces are sucked back into the device, leaving no floating particles that could lead to a blockage elsewhere. The defect is fully removed, and the heart?s function is restored to normal, leaving the child with the prospect of a normal life. The whole minimally invasive process takes place inside a beating heart and would otherwise have required open-heart surgery, with the heart stopped for a cardiopulmonary bypass. PMID:25974909

  4. Precise interpolar phasing of abrupt climate change during the last ice age

    Science.gov (United States)

    WAIS Divide Project Members; Buizert, Christo; Adrian, Betty M.; Ahn, Jinho; Albert, Mary; Alley, Richard B.; Baggenstos, Daniel; Bauska, Thomas K.; Bay, Ryan C.; Bencivengo, Brian B.; Bentley, Charles R.; Brook, Edward J.; Chellman, Nathan J.; Clow, Gary D.; Cole-Dai, Jihong; Conway, Howard; Cravens, Eric; Cuffey, Kurt M.; Dunbar, Nelia W.; Edwards, Jon S.; Fegyveresi, John M.; Ferris, Dave G.; Fitzpatrick, Joan J.; Fudge, T. J.; Gibson, Chris J.; Gkinis, Vasileios; Goetz, Joshua J.; Gregory, Stephanie; Hargreaves, Geoffrey Mill; Iverson, Nels; Johnson, Jay A.; Jones, Tyler R.; Kalk, Michael L.; Kippenhan, Matthew J.; Koffman, Bess G.; Kreutz, Karl; Kuhl, Tanner W.; Lebar, Donald A.; Lee, James E.; Marcott, Shaun A.; Markle, Bradley R.; Maselli, Olivia J.; McConnell, Joseph R.; McGwire, Kenneth C.; Mitchell, Logan E.; Mortensen, Nicolai B.; Neff, Peter D.; Nishiizumi, Kunihiko; Nunn, Richard M.; Orsi, Anais J.; Pasteris, Daniel R.; Pedro, Joel B.; Pettit, Erin C.; Price, P. Buford; Priscu, John C.; Rhodes, Rachael H.; Rosen, Julia L.; Schauer, Andrew J.; Schoenemann, Spruce W.; Sendelbach, Paul J.; Severinghaus, Jeffrey P.; Shturmakov, Alexander J.; Sigl, Michael; Slawny, Kristina R.; Souney, Joseph M.; Sowers, Todd A.; Spencer, Matthew K.; Steig, Eric J.; Taylor, Kendrick C.; Twickler, Mark S.; Vaughn, Bruce H.; Voigt, Donald E.; Waddington, Edwin D.; Welten, Kees C.; Wendricks, Anthony W.; White, James W. C.; Winstrup, Mai; Wong, Gifford J.; Woodruff, Thomas E.

    2015-01-01

    The last glacial period exhibited abrupt Dansgaard–Oeschger climatic oscillations, evidence of which is preserved in a variety of Northern Hemisphere palaeoclimate archives1. Ice cores show that Antarctica cooled during the warm phases of the Greenland Dansgaard–Oeschger cycle and vice versa2, 3, suggesting an interhemispheric redistribution of heat through a mechanism called the bipolar seesaw4, 5, 6. Variations in the Atlantic meridional overturning circulation (AMOC) strength are thought to have been important, but much uncertainty remains regarding the dynamics and trigger of these abrupt events7, 8, 9. Key information is contained in the relative phasing of hemispheric climate variations, yet the large, poorly constrained difference between gas age and ice age and the relatively low resolution of methane records from Antarctic ice cores have so far precluded methane-based synchronization at the required sub-centennial precision2, 3,10. Here we use a recently drilled high-accumulation Antarctic ice core to show that, on average, abrupt Greenland warming leads the corresponding Antarctic cooling onset by 218 ± 92 years (2σ) for Dansgaard–Oeschger events, including the Bølling event; Greenland cooling leads the corresponding onset of Antarctic warming by 208 ± 96 years. Our results demonstrate a north-to-south directionality of the abrupt climatic signal, which is propagated to the Southern Hemisphere high latitudes by oceanic rather than atmospheric processes. The similar interpolar phasing of warming and cooling transitions suggests that the transfer time of the climatic signal is independent of the AMOC background state. Our findings confirm a central role for ocean circulation in the bipolar seesaw and provide clear criteria for assessing hypotheses and model simulations of Dansgaard–Oeschger dynamics.

  5. TIME-SPACE CONCEPT FOR PRECISION MEASUREMENT

    Institute of Scientific and Technical Information of China (English)

    LIU Xiaokang; PENG Donglin; ZHU Ge; WANG Xianquan

    2008-01-01

    The transformation between time and space is discussed. To improve real-time response speed of intelligent measuring system, the concept of exchanging program execution time with more circuitry is presented working in cycle mode. Displacement measuring by magnification is achieved with period measurement by magnification. To change the condition that traditional precision measurement depends on machining precision greatly, the concept of measuring space with time and theory of time-space coordinate transformation are proposed. Guided by the idea of measuring space with time, differential frequency measurement system and time grating displacement sensor are developed based on the proposed novel methods. And high-precision measurement is achieved without high-precision manufacture, which embeds the remarkable characteristics of low cost but high precision to the devices. Experiment and test results conform the validity of the proposed time-space concept.

  6. Resilience-based perspectives to guiding high-nature-value farmland through socioeconomic change

    DEFF Research Database (Denmark)

    Plieninger, Tobias; Bieling, Claudia

    2013-01-01

    Global environmental challenges require approaches that integrate biodiversity conservation, food production, and livelihoods at landscape scales. We reviewed the approach of conserving biodiversity on "high-nature-value" (HNV) farmland, covering 75 million ha in Europe, from a resilience...... conservation efforts for HNV farmland have focused too much on static, isolated, and monosectoral conservation strategies, and that stimulation of resilience and adaptation is essential for guiding HNV farmland through rapid change. © 2013 by the author(s)....

  7. Histological changes at an endosonography-guided biliary drainage site: A case report

    OpenAIRE

    Fujita, Naotaka; Noda, Yutaka; Kobayashi, Go; Ito, Kei; Obana, Takashi; Horaguchi, Jun; Takasawa, Osamu; Nakahara, Kazunari

    2007-01-01

    Endosonography-guided biliary drainage (ESBD) is a new method enabling internal drainage of an obstructed bile duct. However, the histological conditions associated with fistula development via the duodenum to the bile duct have not been reported. We performed ESBD 14 d preoperatively in a patient with an ampullary carcinoma and histologically confirmed changes in and around the fistula. The female patient developed no complications relevant to ESBD. Levels of serum bilirubin and hepatobiliar...

  8. Precision manufacturing

    CERN Document Server

    Dornfeld, David

    2008-01-01

    Today there is a high demand for high-precision products. The manufacturing processes are now highly sophisticated and derive from a specialized genre called precision engineering. Precision Manufacturing provides an introduction to precision engineering and manufacturing with an emphasis on the design and performance of precision machines and machine tools, metrology, tooling elements, machine structures, sources of error, precision machining processes and precision process planning. As well as discussing the critical role precision machine design for manufacturing has had in technological developments over the last few hundred years. In addition, the influence of sustainable manufacturing requirements in precision processes is introduced. Drawing upon years of practical experience and using numerous examples and illustrative applications, David Dornfeld and Dae-Eun Lee cover precision manufacturing as it applies to: The importance of measurement and metrology in the context of Precision Manufacturing. Th...

  9. The precision of glomerular filtration rate determined by Gates method and compared with the results from renal pathological changes

    International Nuclear Information System (INIS)

    Objective: To evaluate the precision of GFR using Gates method and compared with the results from renal pathological changes. Methods: Twenty-seven patients whose 99Tcm-DTPA renograms had no obvious uptake phase were enrolled in Group A, and 27 patients whose 99Tcm-DTPA renograms had obvious uptake phase were enrolled in Group B. The measurement of GFR by Gates method was compared to the creatinine clearance measured and predicted by Cockcroft-Gault (C-G), modification of diet in renal disease (MDRD) and SCr level. Renal pathological changes in two groups were compared using Pearson correlation and t test analysis. Results: In Group A, GFR determined by Gates method did not show correlation with that estimated by C-G or 1/SCr (r = 0.357,0.376, both P>0.05), but was significantly correlated with GFR estimated by MDRD(r=0.440, P99Tcm-DTPA renogram has no obvious uptake phase than that when 99Tcm-DTPA renogram has obvious uptake phase. Renal tubulointerstitial damage is a strong indicator of no obvious uptake phase in 99Tcm-DTPA renogram. (authors)

  10. COP15 for journalists: a guide to the UN climate change summit

    Energy Technology Data Exchange (ETDEWEB)

    Shanahan, Mike

    2009-11-15

    Governments gather in Denmark in December 2009 for what is perhaps the most important meeting since the end of the second world war. December is the deadline they have set themselves for agreeing on action to tackle climate change, and the COP15 conference in Copenhagen is where hopes are high that a new global deal can be struck. This briefing is a guide for journalists reporting on this event, its buildup and its aftermath. It explains key processes, major actions to be agreed and possible outcomes.

  11. The science and politics of global climate change: a guide to the debate

    Science.gov (United States)

    Parson, E. A.; Dessler, A. E.

    2010-12-01

    Our book, "The science and politics of global climate change: A guide to the debate", provides an integrated treatment of the science, technology, economics, policy, and politics of climate change for the educated non-specialist reader. The book explains how scientific and policy debates work, summarizes present scientific knowledge and uncertainty about climate change (including rebutting some common deceptive claims being made to deny the scientific basis for concern), and discusses available options to manage the risks of climate change. We find that widespread confusion arises from the tangling of normative, value-based claims and positive, science-based claims. Combined with arguments over the meaning of uncertainty and its implications for action, this confusion has encouraged the widespread belief that less is known about climate change, and the scientific basis for action to manage climate-change risks is weaker, than is actually the case. Such confusion is common in debates over environmental issues, but in the climate-change debate has been especially promoted by opponents of action to reduce greenhouse gas emissions.

  12. From Planning to Implementation: An Examination of Changes in the Research Design, Sample Size, and Precision of Group Randomized Trials Launched by the Institute of Education Sciences

    Science.gov (United States)

    Spybrook, Jessaca; Puente, Anne Cullen; Lininger, Monica

    2013-01-01

    This article examines changes in the research design, sample size, and precision between the planning phase and implementation phase of group randomized trials (GRTs) funded by the Institute of Education Sciences. Thirty-eight GRTs funded between 2002 and 2006 were examined. Three studies revealed changes in the experimental design. Ten studies…

  13. Resilience-Based Perspectives to Guiding High-Nature-Value Farmland through Socioeconomic Change

    Directory of Open Access Journals (Sweden)

    Tobias Plieninger

    2013-12-01

    Full Text Available Global environmental challenges require approaches that integrate biodiversity conservation, food production, and livelihoods at landscape scales. We reviewed the approach of conserving biodiversity on "high-nature-value" (HNV farmland, covering 75 million ha in Europe, from a resilience perspective. Despite growing recognition in natural resource policies, many HNV farmlands have vanished, and the remaining ones are vulnerable to socioeconomic changes. Using landscape-level cases across Europe, we considered the following social-ecological system properties and components and their integration into HNV farmland management: (1 coupling of social and ecological systems, (2 key variables, (3 adaptive cycles, (4 regime shifts, (5 cascading effects, (6 ecosystem stewardship and collaboration, (7 social capital, and (8 traditional ecological knowledge. We argue that previous conservation efforts for HNV farmland have focused too much on static, isolated, and monosectoral conservation strategies, and that stimulation of resilience and adaptation is essential for guiding HNV farmland through rapid change.

  14. Within-hemifield posture changes affect tactile-visual exogenous spatial cueing without spatial precision, especially in the dark.

    Science.gov (United States)

    Kennett, Steffan; Driver, Jon

    2014-05-01

    We investigated the effects of seen and unseen within-hemifield posture changes on crossmodal visual-tactile links in covert spatial attention. In all experiments, a spatially nonpredictive tactile cue was presented to the left or the right hand, with the two hands placed symmetrically across the midline. Shortly after a tactile cue, a visual target appeared at one of two eccentricities within either of the hemifields. For half of the trial blocks, the hands were aligned with the inner visual target locations, and for the remainder, the hands were aligned with the outer target locations. In Experiments 1 and 2, the inner and outer eccentricities were 17.5º and 52.5º, respectively. In Experiment 1, the arms were completely covered, and visual up-down judgments were better when on the same side as the preceding tactile cue. Cueing effects were not significantly affected by hand or target alignment. In Experiment 2, the arms were in view, and now some target responses were affected by cue alignment: Cueing for outer targets was only significant when the hands were aligned with them. In Experiment 3, we tested whether any unseen posture changes could alter the cueing effects, by widely separating the inner and outer target eccentricities (now 10º and 86º). In this case, hand alignment did affect some of the cueing effects: Cueing for outer targets was now only significant when the hands were in the outer position. Although these results confirm that proprioception can, in some cases, influence tactile-visual links in exogenous spatial attention, they also show that spatial precision is severely limited, especially when posture is unseen. PMID:24470256

  15. Preface: Monitoring and modelling to guide coastal adaptation to extreme storm events in a changing climate

    Science.gov (United States)

    Brown, J. M.; Ciavola, P.; Masselink, G.; McCall, R.; Plater, A. J.

    2016-02-01

    Storms across the globe and their associated consequences in coastal zones (flooding and erosion), combined with the long-term geomorphic evolution of our coastlines, are a threat to life and assets, both socioeconomic and environmental. In a changing climate, with a rising global sea level, potentially changing patterns in storm tracks and storminess, and rising population density and pressures on the coastal zone, the future risk of coastal storm impacts is likely to increase. Coastal managers and policy makers therefore need to make effective and timely decisions on the use of resources for the immediate and longer Research focused on "monitoring and modelling to guide coastal adaptation to extreme storm events in a changing climate" is becoming more common; its goal is to provide science-based decision support for effective adaptation to the consequences of storm impacts, both now and under future climate scenarios at the coast. The growing transfer of information between the science community and end-users is enabling leading research to have a greater impact on the socioeconomic resilience of coastal communities. This special issue covers recent research activities relating to coastal hazard mapping in response to extreme events, economic impacts of long-term change, coastal processes influencing management decisions and the development of online decision support tools.

  16. Evaluation of time-related changes in lung detail findings after radiation therapy to the chest using multidetector-row CT. Usefulness of precision scanning

    International Nuclear Information System (INIS)

    Time-related changes in lung detail findings after radiation therapy to the chest were evaluated using multidetector-row CT. The frequency of individual findings and time-related changes in percent incidence of findings were compared between ordinary scanning at 3 mm raw thickness and 8 mm recon thickness, and precision scanning set at 0.5 mm for both parameters. For both scanning methods, the most frequently detected finding was ground-glass opacity (GGO). For all findings other than GGO and consolidation, the frequency of detection was greater with precision scanning than with ordinary scanning. GGO was also the finding showing the greatest difference in frequency of detection between the two scanning methods; because ordinary scanning tended to overvalue GGO, a demonstrative experiment was conducted using a lung detail phantom. Regarding time-related changes in percent incidence of findings, precision scanning was equivalent or superior to ordinary scanning at all time points except after 3 months. These results, combined with the more accurate evaluation of various lung detail changes after radiation therapy to the chest, including GGO (reversible lesion), suggest the usefulness of precision scanning in combination with ordinary scanning. (author)

  17. Adapting to climate change in forest based land use systems: A guide to strategy

    Energy Technology Data Exchange (ETDEWEB)

    Secrett, C.M.

    1996-12-31

    The prospect of climate change and sea level rise as a result of greenhouse gas emissions presents a serious challenge to decision-makers concerned with ensuring sustainable development. This report provides a guide to means of reducing the potential impact of the global warming problem on the forest sector whilst ensuring that more immediate development priorities are met. The most effective response strategy will be one that simultaneously brings both immediate development and longer-term adaptive benefits. This report outlines ways of constructing an adaptive response strategy that can help achieve these ends. The approach is referred to as sustainable adaptation. A prototype methodological framework of the sustainable adaptation approach has been provided with the summary. The first priority of sustainable adaption is to base climate change responses on actions that meet basic ecological and social needs now and in the future. Solutions should necessarily include relieving current development pressures in the tropical forest sector. The key is to couple adaptive responses to climate change with sustainable development solutions to present-day forest use problems. Implementing adaptive land-use policies and management practices which are likely to minimise the adverse impacts of anticipated climate change should meet current sustainable management goals. Implementing sustainable land-use and forestry management practices should meet adaptation goals. This report presents a discussion of the fundamental issues underlying the development of a sustainable adaptation strategy and a prototype methodological framework. The findings are based on case studies conducted in Central America (Costa Rica and Nicaragua); SADCC countries in Africa (Zimbabwe, Botswana, Tanzania); and Asia (Vietnam). 450 refs

  18. Why precision?

    Energy Technology Data Exchange (ETDEWEB)

    Bluemlein, Johannes

    2012-05-15

    Precision measurements together with exact theoretical calculations have led to steady progress in fundamental physics. A brief survey is given on recent developments and current achievements in the field of perturbative precision calculations in the Standard Model of the Elementary Particles and their application in current high energy collider data analyses.

  19. Why precision?

    International Nuclear Information System (INIS)

    Precision measurements together with exact theoretical calculations have led to steady progress in fundamental physics. A brief survey is given on recent developments and current achievements in the field of perturbative precision calculations in the Standard Model of the Elementary Particles and their application in current high energy collider data analyses.

  20. 76 FR 7810 - Notice of Proposed Change to Section I of the South Dakota and North Dakota State Technical Guides

    Science.gov (United States)

    2011-02-11

    ...The NRCS State Conservationists for South Dakota and North Dakota have determined that changes must be made to the NRCS State Technical Guides concerning State wetland mapping conventions. The two States are proposing to issue joint State wetland mapping conventions. The joint State wetland mapping conventions will be used as part of the technical documents to conduct wetland determinations on......

  1. BioCore Guide: A Tool for Interpreting the Core Concepts of Vision and Change for Biology Majors

    Science.gov (United States)

    Brownell, Sara E.; Freeman, Scott; Wenderoth, Mary Pat; Crowe, Alison J.

    2014-01-01

    "Vision and Change in Undergraduate Biology Education" outlined five core concepts intended to guide undergraduate biology education: 1) evolution; 2) structure and function; 3) information flow, exchange, and storage; 4) pathways and transformations of energy and matter; and 5) systems. We have taken these general recommendations and…

  2. Local collectivities and climatic change. Are you ready? A guide for the adaptation devoted to the local collectivities

    International Nuclear Information System (INIS)

    Facing the climatic change effects, it is necessary to develop a national but also regional adaptation policy to the global warming. This guide aims to give, to the local managers, information on the global warming and bring possible adaptation measures. The sectors of planning, buildings, transports, public health, environment and public information are discussed. (A.L.B.)

  3. The Changes of Tear Status after Conventional and Wavefront-Guided IntraLASIK

    Science.gov (United States)

    Foo, Say Kiang; Kaur, Sharanjeet; Abd Manan, Faudziah; Low, Aloysius Joseph

    2011-01-01

    Background: IntraLASIK is a LASIK surgery that involved IntraLase femtosecond laser for the corneal flap creating. The objective of this research was to investigate and compare the changes in tear status at 1 and 3 months after undergoing conventional IntraLASIK with Bausch & Lomb PlanoScan (PS) algorithm, Bausch & Lomb Zyoptix Tissue Saving (ZTS) algorithm, and wavefront-guided (WG) IntraLASIK with VISX CustomVue. Methods: Tear status of 36 patients who were divided into 3 groups depending on the type of IntraLASIK they underwent (PS, n = 13; ZTS, n = 9; WG, n = 14) was evaluated. Tear status was determined by classifying the category of the thickness of pre-corneal tear lipid layer, non-invasive tear break-up time, and tear meniscus height. Repeated measures analysis of variance (ANOVA) and one way ANOVA were used for the statistical analyses. Results: The category of the thickness of tear lipid layer, non-invasive tear break up time and tear meniscus height were neither significantly changed after IntraLASIK for all groups nor showed significant difference among groups at 1 and 3 months post-IntraLASIK (P > 0.05). Blinking rate and palpebral aperture also had no significant changed after IntraLASIK. Conclusion: Both conventional (PS and ZTS) and WG IntraLASIK did not affect tear status up to 3 months post-IntraLASIK. WG IntraLASIK did not show superiority in preserving tear status 1 and 3 months post-surgery compared with conventional IntraLASIK. PMID:22135584

  4. Learning to guide behavior change : physical therapists’ promotion of health-enhancing physical activity in people with rheumatoid arthritis

    OpenAIRE

    Nessen, Thomas

    2016-01-01

    Background and Aim: Physical activity is important for management of rheumatoid arthritis (RA). In the Physical Activity in RA (PARA) 2010 study physical therapists (PTs) delivered a one-year health-enhancing physical activity (HEPA) intervention in people with RA. The PTs’ guided behavior change by structured use of behavior change techniques (BCTs) and adapted a biopsychosocial approach during biweekly support group sessions. Since this may not be mainstream practice for PTs ...

  5. BioCore Guide: A Tool for Interpreting the Core Concepts of Vision and Change for Biology Majors

    OpenAIRE

    Brownell, Sara E.; Freeman, Scott; Wenderoth, Mary Pat; Crowe, Alison J.

    2014-01-01

    Vision and Change in Undergraduate Biology Education outlined five core concepts intended to guide undergraduate biology education: 1) evolution; 2) structure and function; 3) information flow, exchange, and storage; 4) pathways and transformations of energy and matter; and 5) systems. We have taken these general recommendations and created a Vision and Change BioCore Guide—a set of general principles and specific statements that expand upon the core concepts, creating a framework that biolog...

  6. Flight control and landing precision in the nocturnal bee Megalopta is robust to large changes in light intensity

    Directory of Open Access Journals (Sweden)

    Emily eBaird

    2015-10-01

    Full Text Available Like its diurnal relatives, Megalopta genalis use visual information to control flight. Unlike their diurnal relatives, however, they do this at extremely low light intensities. Although Megalopta has developed optical specialisations to increase visual sensitivity, theoretical studies suggest that this enhanced sensitivity does not enable them to capture enough light to use visual information to reliably control flight in the rainforest at night. It has been proposed that Megalopta gain extra sensitivity by summing visual information over time. While enhancing the reliability of vision, this strategy would decrease the accuracy with which they can detect image motion - a crucial cue for flight control. Here, we test this temporal summation hypothesis by investigating how Megalopta’s flight control and landing precision is affected by light intensity and compare our findings with the results of similar experiments performed on the diurnal bumblebee Bombus terrestris, to explore the extent to which Megalopta’s adaptations to dim light affect their precision. We find that, unlike Bombus, light intensity does not affect flight and landing precision in Megalopta. Overall, we find little evidence that Megalopta uses a temporal summation strategy in dim light, while we find strong support for the use of this strategy in Bombus.

  7. Performance analysis of axial flow pump on gap changing between impeller and guide vane

    International Nuclear Information System (INIS)

    In order to study the influence on gap changing of the static and dynamic components in axial flow pump, the axial flow pump model (TJ04-ZL-06) that used in the eastern of south-to-north water diversion project was selected. Steady turbulence field with different gaps was simulated by standard κ-ε turbulence model and double-time stepping methods. Information on the pressure distribution and velocity distribution of impeller surfaces were obtained. Then, calculated results were compared with the test results and analyzed. The results show that the performance of pump is not sensitive with the axial gap width under design conditions and the large flow rate condition. With increasing gap width, it will be improved in low flow rate condition. The attack angle of impeller inlet in small flow rate condition become small and the flow separation phenomenon can be observed in this condition. The axial velocity distribution of impeller outlet is nonlinear and to increase the axial gap is to improve the flow pattern near the hub effectively. The trend of calculating results is identical with test. It will play a guiding role to the axial pump operation and design in south-to-north water diversion project

  8. Intelligent Transportation Systems: Automated Guided Vehicle Systems in Changing Logistics Environments

    Science.gov (United States)

    Schulze, L.; Behling, S.; Buhrs, S.

    2008-06-01

    The usage of Automated Guided Vehicle Systems (AGVS) is growing. This has not always been the case in the past. A new record of the sells numbers is the result of inventive developments, new applications and modern thinking. One market that AGVS were not able to thoroughly conquer yet were rapidly changing logistics environments. The advantages in recurrent transportation with AGVS used to be hindered by the needs of flexibility. When nowadays managers talk about Flexible Manufacturing Systems (FMS) there is no reason not to consider AGVS. Fixed guidelines, permanent transfer stations and static routes are no necessity for most AGVS producers. Flexible Manufacturing Systems can raise profitability with AGVS. When robots start saving billions in production costs, the next step at same plants are automated materials handling systems. Today, there are hundreds of instances of computer-controlled systems designed to handle and transport materials, many of which have replaced conventional human-driven platform trucks. Reduced costs due to damages and failures, tracking and tracing as well as improved production scheduling on top of fewer personnel needs are only some of the advantages.

  9. SU-E-P-54: Evaluation of the Accuracy and Precision of IGPS-O X-Ray Image-Guided Positioning System by Comparison with On-Board Imager Cone-Beam Computed Tomography

    International Nuclear Information System (INIS)

    Purpose: The purpose of this study is to assess the positioning accuracy and precision of IGPS-O system which is a novel radiographic kilo-voltage x-ray image-guided positioning system developed for clinical IGRT applications. Methods: IGPS-O x-ray image-guided positioning system consists of two oblique sets of radiographic kilo-voltage x-ray projecting and imaging devices which were equiped on the ground and ceiling of treatment room. This system can determine the positioning error in the form of three translations and three rotations according to the registration of two X-ray images acquired online and the planning CT image. An anthropomorphic head phantom and an anthropomorphic thorax phantom were used for this study. The phantom was set up on the treatment table with correct position and various “planned” setup errors. Both IGPS-O x-ray image-guided positioning system and the commercial On-board Imager Cone-beam Computed Tomography (OBI CBCT) were used to obtain the setup errors of the phantom. Difference of the Result between the two image-guided positioning systems were computed and analyzed. Results: The setup errors measured by IGPS-O x-ray image-guided positioning system and the OBI CBCT system showed a general agreement, the means and standard errors of the discrepancies between the two systems in the left-right, anterior-posterior, superior-inferior directions were −0.13±0.09mm, 0.03±0.25mm, 0.04±0.31mm, respectively. The maximum difference was only 0.51mm in all the directions and the angular discrepancy was 0.3±0.5° between the two systems. Conclusion: The spatial and angular discrepancies between IGPS-O system and OBI CBCT for setup error correction was minimal. There is a general agreement between the two positioning system. IGPS-O x-ray image-guided positioning system can achieve as good accuracy as CBCT and can be used in the clinical IGRT applications

  10. Ratification of the Kyoto Protocol: a citizen's guide to the Canadian climate change policy process

    International Nuclear Information System (INIS)

    Canada is faced with the important decision of whether it should ratify the Kyoto Protocol. A reference for stakeholders and non-expert interested parties, this document is a guide into the Canadian Climate Change Policy Process. An understanding of climate science is required for climate policy, as is a knowledge of policy options available to overcome the challenges posed by climate change. The situation is further complicated by international and federal-provincial negotiations over the measures that should be implemented, if any. Climate policy affects all aspects of our lives, especially how we produce and use energy. An overview of climate science is provided in the first section, and the relationship between climate and rising temperatures due to greenhouse gas emissions is established. The sources of greenhouse gases in Canada are identified, with a closer look at the current trends. The Kyoto Protocol, if ratified, calls for Canada to reduce its emissions of greenhouse gases to six per cent below 1990 levels. It is noted that to date, Canada's emissions have risen 19.7 per cent above 1990 levels. The process underlying the international negotiations associated with the Kyoto Protocol, and especially Canada's role in it, are discussed. Flexibility mechanisms are strongly supported by Canada, such as credits for sinks, international carbon trading and credits for Clean Energy Exports. By approving such measures, the integrity of the Protocol would be considerably weakened. The domestic policy-making environment is examined, presenting key federal, provincial business and environmental players. In addition, the policy process in Canada is described, as well as the decisions made up to September 2002. Bibliographic and contact information is added in the last section of the document. 89 refs., 7 tabs., 7 figs

  11. Task-dependent changes of motor cortical network excitability during precision grip compared to isolated finger contraction

    DEFF Research Database (Denmark)

    Kouchtir-Devanne, Nezha; Capaday, Charles; Cassim, François;

    2012-01-01

    The purpose of this study was to determine whether task-dependent differences in corticospinal pathway excitability occur in going from isolated contractions of the index finger to its coordinated activity with the thumb. Focal transcranial magnetic stimulation (TMS) was used to measure input...... similar between the two tasks. Short- and long-latency intracortical inhibitions (SICI and LICI, respectively) were also measured in each task. Both measures of inhibition decreased during precision grip compared with the isolated contraction. The results demonstrate that the motor cortical circuits...

  12. Sonoanatomical Change of Phrenic Nerve According to Posture During Ultrasound-Guided Stellate Ganglion Block

    Science.gov (United States)

    Joeng, Eui Soo; Jeong, Young Cheol; Park, Bum Jun; Kang, Seok; Yang, Seung Nam

    2016-01-01

    Objective To evaluate the risk of phrenic nerve injury during ultrasound-guided stellate ganglion block (US-SGB) according to sonoanatomy of the phrenic nerve, and determine a safer posture for needle insertion by assessing its relationship with surrounding structure according to positional change. Methods Twenty-nine healthy volunteers were recruited and underwent ultrasound in two postures, i.e., supine position with the neck extension and head rotation, and lateral decubitus position. The transducer was placed at the anterior tubercle of the C6 level to identify phrenic nerve. The cross-sectional area (CSA), depth from skin, distance between phrenic nerve and anterior tubercle of C6 transverse process, and the angle formed by anterior tubercle, posterior tubercle and phrenic nerve were measured. Results The phrenic nerve was clearly identified in the intermuscular fascia layer between the anterior scalene and sternocleidomastoid muscles. The distance between the phrenic nerve and anterior tubercle was 10.33±3.20 mm with the supine position and 9.20±3.31 mm with the lateral decubitus position, respectively. The mean CSA and skin depth of phrenic nerve were not statistically different between the two positions. The angle with the supine position was 48.37°±27.43°, and 58.89°±30.02° with the lateral decubitus position. The difference of angle between the two positions was statistically significant. Conclusion Ultrasound is a useful tool for assessing the phrenic nerve and its anatomical relation with other cervical structures. In addition, lateral decubitus position seems to be safer by providing wider angle for needle insertion than the supine position in US-SGB. PMID:27152274

  13. Advances of Precise Radiotherapy for Lung Cancer

    OpenAIRE

    Xin WANG; Xu, Feng; Wei, Yuquan

    2011-01-01

    At present lung tumor radiation therapy has entered the accurate radiotherapy era. Precise radiotherapy includes intensity modulated radiotherapy (IMRT), image-guided radiotherapy (IGRT) and stereotactic body radiotherapy (SBRT). During the process of implementing precise radiotherapy, these problems should be fully considered to ensure executing precise radiotherapy accurately: patient positioning, controlling of the lung tumor motion, selecting of image techniques, PTV margin, dose prescrip...

  14. Precision glasscutter

    Science.gov (United States)

    Coombs, D. S.

    1974-01-01

    Glass is positioned against preset stops; and glasscutter, which is permanently mounted in carrier support by cutter guide rails, is used to scribe glass at predetermined length. Glass is placed against predetermined groove at opposite end to correspond with setting of cutter carrier support and it is broken on end of cutter base.

  15. A FRET-guided, NIR-responsive bubble-generating liposomal system for in vivo targeted therapy with spatially and temporally precise controlled release.

    Science.gov (United States)

    Chuang, Er-Yuan; Lin, Chia-Chen; Chen, Ko-Jie; Wan, De-Hui; Lin, Kun-Ju; Ho, Yi-Cheng; Lin, Po-Yen; Sung, Hsing-Wen

    2016-07-01

    The nonspecific distribution of therapeutic agents and nontargeted heating commonly produce undesirable side effects during cancer treatment since the optimal timing of triggering the carrier systems is unknown. This work proposes a multifunctional liposomal system that can intracellularly and simultaneously deliver the therapeutic drug doxorubicin (DOX), heat, and a bubble-generating agent (ammonium bicarbonate, ABC) into targeted tumor cells to have a cytotoxic effect. Gold nanocages that are encapsulated in liposomes effectively convert near-infrared light irradiation into localized heat, which causes the decomposition of ABC and generates CO2 bubbles, rapidly triggering the release of DOX. Additionally, a hybridized Mucin-1 aptamer is conjugated on the surface of the test liposomes, which then function as a recognition probe to enhance the uptake of those liposomes by cells, and as a molecular beacon to signal when the internalized particles have been maximized, which is the optimal time for photothermally triggering the release of the drug following the systemic administration of the liposomes. Empirical results reveal that this combined treatment effectively controls targeted drug release in a spatially and temporally precise fashion and so significantly increases the potency of the drug while minimizing unwanted side effects, making it a promising treatment for cancer. PMID:27070992

  16. “Cancer 2015”: A Prospective, Population-Based Cancer Cohort—Phase 1: Feasibility of Genomics-Guided Precision Medicine in the Clinic

    Directory of Open Access Journals (Sweden)

    John P. Parisot

    2015-10-01

    Full Text Available “Cancer 2015” is a longitudinal and prospective cohort. It is a phased study whose aim was to pilot recruiting 1000 patients during phase 1 to establish the feasibility of providing a population-based genomics cohort. Newly diagnosed adult patients with solid cancers, with residual tumour material for molecular genomics testing, were recruited into the cohort for the collection of a dataset containing clinical, molecular pathology, health resource use and outcomes data. 1685 patients have been recruited over almost 3 years from five hospitals. Thirty-two percent are aged between 61–70 years old, with a median age of 63 years. Diagnostic tumour samples were obtained for 90% of these patients for multiple parallel sequencing. Patients identified with somatic mutations of potentially “actionable” variants represented almost 10% of those tumours sequenced, while 42% of the cohort had no mutations identified. These genomic data were annotated with information such as cancer site, stage, morphology, treatment and patient outcomes and health resource use and cost. This cohort has delivered its main objective of establishing an upscalable genomics cohort within a clinical setting and in phase 2 aims to develop a protocol for how genomics testing can be used in real-time clinical decision-making, providing evidence on the value of precision medicine to clinical practice.

  17. "Cancer 2015": A Prospective, Population-Based Cancer Cohort-Phase 1: Feasibility of Genomics-Guided Precision Medicine in the Clinic.

    Science.gov (United States)

    Parisot, John P; Thorne, Heather; Fellowes, Andrew; Doig, Ken; Lucas, Mark; McNeil, John J; Doble, Brett; Dobrovic, Alexander; John, Thomas; James, Paul A; Lipton, Lara; Ashley, David; Hayes, Theresa; McMurrick, Paul; Richardson, Gary; Lorgelly, Paula; Fox, Stephen B; Thomas, David M

    2015-01-01

    "Cancer 2015" is a longitudinal and prospective cohort. It is a phased study whose aim was to pilot recruiting 1000 patients during phase 1 to establish the feasibility of providing a population-based genomics cohort. Newly diagnosed adult patients with solid cancers, with residual tumour material for molecular genomics testing, were recruited into the cohort for the collection of a dataset containing clinical, molecular pathology, health resource use and outcomes data. 1685 patients have been recruited over almost 3 years from five hospitals. Thirty-two percent are aged between 61-70 years old, with a median age of 63 years. Diagnostic tumour samples were obtained for 90% of these patients for multiple parallel sequencing. Patients identified with somatic mutations of potentially "actionable" variants represented almost 10% of those tumours sequenced, while 42% of the cohort had no mutations identified. These genomic data were annotated with information such as cancer site, stage, morphology, treatment and patient outcomes and health resource use and cost. This cohort has delivered its main objective of establishing an upscalable genomics cohort within a clinical setting and in phase 2 aims to develop a protocol for how genomics testing can be used in real-time clinical decision-making, providing evidence on the value of precision medicine to clinical practice. PMID:26529019

  18. “Cancer 2015”: A Prospective, Population-Based Cancer Cohort—Phase 1: Feasibility of Genomics-Guided Precision Medicine in the Clinic

    Science.gov (United States)

    Parisot, John P.; Thorne, Heather; Fellowes, Andrew; Doig, Ken; Lucas, Mark; McNeil, John J.; Doble, Brett; Dobrovic, Alexander; John, Thomas; James, Paul A.; Lipton, Lara; Ashley, David; Hayes, Theresa; McMurrick, Paul; Richardson, Gary; Lorgelly, Paula; Fox, Stephen B.; Thomas, David M.

    2015-01-01

    “Cancer 2015” is a longitudinal and prospective cohort. It is a phased study whose aim was to pilot recruiting 1000 patients during phase 1 to establish the feasibility of providing a population-based genomics cohort. Newly diagnosed adult patients with solid cancers, with residual tumour material for molecular genomics testing, were recruited into the cohort for the collection of a dataset containing clinical, molecular pathology, health resource use and outcomes data. 1685 patients have been recruited over almost 3 years from five hospitals. Thirty-two percent are aged between 61–70 years old, with a median age of 63 years. Diagnostic tumour samples were obtained for 90% of these patients for multiple parallel sequencing. Patients identified with somatic mutations of potentially “actionable” variants represented almost 10% of those tumours sequenced, while 42% of the cohort had no mutations identified. These genomic data were annotated with information such as cancer site, stage, morphology, treatment and patient outcomes and health resource use and cost. This cohort has delivered its main objective of establishing an upscalable genomics cohort within a clinical setting and in phase 2 aims to develop a protocol for how genomics testing can be used in real-time clinical decision-making, providing evidence on the value of precision medicine to clinical practice. PMID:26529019

  19. SU-E-J-47: Development of a High-Precision, Image-Guided Radiotherapy, Multi- Purpose Radiation Isocenter Quality-Assurance Calibration and Checking System

    International Nuclear Information System (INIS)

    Purpose: To develop a system that can define the radiation isocenter and correlate this information with couch coordinates, laser alignment, optical distance indicator (ODI) settings, optical tracking system (OTS) calibrations, and mechanical isocenter walkout. Methods: Our team developed a multi-adapter, multi-purpose quality assurance (QA) and calibration device that uses an electronic portal imaging device (EPID) and in-house image-processing software to define the radiation isocenter, thereby allowing linear accelerator (Linac) components to be verified and calibrated. Motivated by the concept that each Linac component related to patient setup for image-guided radiotherapy based on cone-beam CT should be calibrated with respect to the radiation isocenter, we designed multiple concentric adapters of various materials and shapes to meet the needs of MV and KV radiation isocenter definition, laser alignment, and OTS calibration. The phantom's ability to accurately define the radiation isocenter was validated on 4 Elekta Linacs using a commercial ball bearing (BB) phantom as a reference. Radiation isocenter walkout and the accuracy of couch coordinates, ODI, and OTS were then quantified with the device. Results: The device was able to define the radiation isocenter within 0.3 mm. Radiation isocenter walkout was within ±1 mm at 4 cardinal angles. By switching adapters, we identified that the accuracy of the couch position digital readout, ODI, OTS, and mechanical isocenter walkout was within sub-mm. Conclusion: This multi-adapter, multi-purpose isocenter phantom can be used to accurately define the radiation isocenter and represents a potential paradigm shift in Linac QA. Moreover, multiple concentric adapters allowed for sub-mm accuracy for the other relevant components. This intuitive and user-friendly design is currently patent pending

  20. High-precision dating and correlation of ice, marine and terrestrial sequences spanning Heinrich Event 3: Testing mechanisms of interhemispheric change using New Zealand ancient kauri (Agathis australis)

    Science.gov (United States)

    Turney, Chris S. M.; Palmer, Jonathan; Bronk Ramsey, Christopher; Adolphi, Florian; Muscheler, Raimund; Hughen, Konrad A.; Staff, Richard A.; Jones, Richard T.; Thomas, Zoë A.; Fogwill, Christopher J.; Hogg, Alan

    2016-04-01

    Robustly testing hypotheses of geographic synchroneity of abrupt and extreme change during the late Pleistocene (60,000 to 11,650 years ago) requires a level of chronological precision often lacking in ice, marine and terrestrial sequences. Here we report a bidecadally-resolved New Zealand kauri (Agathis australis) tree-ring sequence spanning two millennia that preserves a record of atmospheric radiocarbon (14C) during ice-rafted debris event Heinrich Event 3 (HE3) in the North Atlantic and Antarctic Isotope Maximum 4 (AIM4) in the Southern Hemisphere. Using 14C in the marine Cariaco Basin and 10Be preserved in Greenland ice, the kauri 14C sequence allows us to precisely align sequences across this period. We observe no significant difference between atmospheric and marine 14C records during HE3, suggesting no stratification of surface waters and collapse in Atlantic Meridional Overturning Circulation (AMOC). Instead our results support recent evidence for a weakened AMOC across at least two millennia of the glacial period. Our work adds to a growing body of literature confirming that Heinrich events are not the cause of stadial cooling and suggests changes in the AMOC were not the primary driver of antiphase temperature trends between the hemispheres. Decadally-resolved 14C in ancient kauri offers a powerful new (and complementary) approach to polar ice core CH4 alignment for testing hypotheses of abrupt and extreme climate change.

  1. Automatically gated image-guided breath-hold IMRT is a fast, precise, and dosimetrically robust treatment for lung cancer patients

    International Nuclear Information System (INIS)

    delivery precision for patients with small and larger lung tumors. (orig.)

  2. Skills for the Changing Workplace: An Automotive Repair Instructor's Guide. Research and Development Series No. 256.

    Science.gov (United States)

    Bhaerman, Robert D.; North, Ricke A.

    This guide was developed to assist vocational instructors in automotive repair programs in presenting broadly applicable nontechnical (often called quality of work life--QWL) skills, such as interpersonal and group process skills, problem solving and decision making, planning, communications, reasoning skills, and organizational management skills.…

  3. Changes in persistent delusions in schizophrenia using guided self-determination

    DEFF Research Database (Denmark)

    Jørgensen, Rikke; Hansson Professor, Lars; Zoffmann, Vibeke

    2012-01-01

    Delusions in persons with schizophrenia who have limited insight have been targeted with different treatment modalities with equivocal results. Working with the Guided Self-Determination method used in shared decision-making and problem solving, a 55-year-old male diagnosed with schizophrenia...

  4. From mandatory icebreaker guiding to a permission regime:changes to the new Russian legislation of the Northern Sea Route

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xia; ZOU Leilei; TU Jingfang; QIAN Zongqi; WANG Zeming; YANG Huigen

    2014-01-01

    This article focuses on two issues. The first concerns definitions of the Northern Sea Route (NSR) in old and new Russian legislation, and the second relates to Russian rules on icebreaker guiding. Based on a comprehensive comparative analysis of relevant Russian legal provisions enacted in 2013 and previous laws in this area, we offer the following conclusions. (1) Our legal analysis indicates that Russia’s view of the NSR as a historical national transportation route has not changed. However, the new law redefines the scope and coverage of the NSR, which now comprises the internal waters, territorial sea, adjacent zone, and the exclusive economic zone of the Russian Federation. In fact, the new law resolves previous ambiguity regarding extension of the NSR boundary to the high seas. (2) Based on an analysis of the new rules on icebreaker guiding, the article concludes that NSR is transitioning from a mandatory icebreaker guiding regime into a permit regime. This is particularly evident in its provision of a concrete, practical, and predictable clause on permissible or impermissible conditions relating to independent navigation. According to the new rules, it is possible for foreign ships to undertake independent navigation in the NSR. The Russian NSR policy, therefore, appears to have changed significantly, and has future potential for opening the NSR up to the international community.

  5. Within-hemifield posture changes affect tactile–visual exogenous spatial cueing without spatial precision, especially in the dark

    OpenAIRE

    Kennett, Steffan; Driver, Jon

    2014-01-01

    We investigated the effects of seen and unseen within-hemifield posture changes on crossmodal visual–tactile links in covert spatial attention. In all experiments, a spatially nonpredictive tactile cue was presented to the left or the right hand, with the two hands placed symmetrically across the midline. Shortly after a tactile cue, a visual target appeared at one of two eccentricities within either of the hemifields. For half of the trial blocks, the hands were aligned with the inner visual...

  6. Automatically gated image-guided breath-hold IMRT is a fast, precise, and dosimetrically robust treatment for lung cancer patients

    Energy Technology Data Exchange (ETDEWEB)

    Simeonova-Chergou, Anna; Jahnke, Anika; Siebenlist, Kerstin; Stieler, Florian; Mai, Sabine; Boda-Heggemann, Judit; Wenz, Frederik; Lohr, Frank; Jahnke, Lennart [University Medical Center Mannheim, University of Heidelberg, Department of Radiotherapy and Oncology, Mannheim (Germany)

    2016-03-15

    delivery precision for patients with small and larger lung tumors. (orig.) [German] Die Hochdosisstrahlentherapie des Bronchialkarzinoms ist eine Herausforderung. Bis zu 2 cm kann sich der Tumor in kraniokaudaler und anteroposteriorer Richtung bewegen - abhaengig vom Atemzyklus. Die Tumorverschiebung nimmt mit der Behandlungsdauer zu, was also die Behandlungsunsicherheit vermehrt. In der vorliegenden Studie wurde untersucht, ob die automatisch gesteuerte, Cone-Beam-Computertomographie(CBCT)-kontrollierte, intensitaetsmodulierte stereotaktische Strahlentherapie (''stereotactic body radiation therapy'', SBRT) im Atemanhalt nach schneller tiefer Inspiration (''deep inspiration breath hold'', DIBH) ohne Ausgleichskoerper (''flattening filter free'', FFF) und die mit einem Ausgleichskoerper applizierte normal fraktionierte intensitaetsmodulierte DIBH-Strahlentherapie/volumenmodulierte Strahlentherapie mit Rotation des Bestrahlungsarms (''volumetric-modulated arc therapy'', VMAT) der Lunge mit ausreichender Genauigkeit innerhalb eines klinisch akzeptablen Zeitfensters angewendet werden koennen. Die Bestrahlungsplaene von 34 Patienten mit Bronchialkarzinomen wurden ausgewertet. Von diesen Patienten erhielten 17 eine computergesteuerte SBRT mit schneller DIBH und einer Dosis von 60 Gy (5 Fraktionen a 12 Gy oder 12 Fraktionen a 5 Gy) in FFF-VMAT-Technik (FFF-SBRT) jeden 2. Tag, und 17 erhielten eine konventionelle VMAT mit Ausgleichskoerper (conv-VMAT) und taeglichen Teildosen von 2 Gy (kumulative Dosis: 50-70 Gy). Fuer Plaene mit FFF-SBRT waren mehr Ueberwachungseinheiten (''monitor units'', MU) erforderlich als fuer Plaene mit con-VMAT (2956,6 ± 885,3 MU fuer 12 Gy/Fraktion bzw. 1148,7 ± 289,2 MU fuer 5 Gy/Fraktion vs. 608,4 ± 157,5 MU fuer 2 Gy/Fraktion). Die Dauer der Gesamttherapie und der Beam-on-Zeit (''Strahl ein'') waren fuer FFF-SBRT-Plaene kuerzer

  7. Changes in the Precision of a Study from Planning Phase to Implementation Phase: Evidence from the First Wave of Group Randomized Trials Launched by the Institute of Education Sciences

    Science.gov (United States)

    Spybrook, Jessaca; Lininger, Monica; Cullen, Anne

    2011-01-01

    The purpose of this study is to extend the work of Spybrook and Raudenbush (2009) and examine how the research designs and sample sizes changed from the planning phase to the implementation phase in the first wave of studies funded by IES. The authors examine the impact of the changes in terms of the changes in the precision of the study from the…

  8. Guidelines for Dual Energy X-Ray Absorptiometry Analysis of Trabecular Bone-Rich Regions in Mice: Improved Precision, Accuracy, and Sensitivity for Assessing Longitudinal Bone Changes.

    Science.gov (United States)

    Shi, Jiayu; Lee, Soonchul; Uyeda, Michael; Tanjaya, Justine; Kim, Jong Kil; Pan, Hsin Chuan; Reese, Patricia; Stodieck, Louis; Lin, Andy; Ting, Kang; Kwak, Jin Hee; Soo, Chia

    2016-05-01

    Trabecular bone is frequently studied in osteoporosis research because changes in trabecular bone are the most common cause of osteoporotic fractures. Dual energy X-ray absorptiometry (DXA) analysis specific to trabecular bone-rich regions is crucial to longitudinal osteoporosis research. The purpose of this study is to define a novel method for accurately analyzing trabecular bone-rich regions in mice via DXA. This method will be utilized to analyze scans obtained from the International Space Station in an upcoming study of microgravity-induced bone loss. Thirty 12-week-old BALB/c mice were studied. The novel method was developed by preanalyzing trabecular bone-rich sites in the distal femur, proximal tibia, and lumbar vertebrae via high-resolution X-ray imaging followed by DXA and micro-computed tomography (micro-CT) analyses. The key DXA steps described by the novel method were (1) proper mouse positioning, (2) region of interest (ROI) sizing, and (3) ROI positioning. The precision of the new method was assessed by reliability tests and a 14-week longitudinal study. The bone mineral content (BMC) data from DXA was then compared to the BMC data from micro-CT to assess accuracy. Bone mineral density (BMD) intra-class correlation coefficients of the new method ranging from 0.743 to 0.945 and Levene's test showing that there was significantly lower variances of data generated by new method both verified its consistency. By new method, a Bland-Altman plot displayed good agreement between DXA BMC and micro-CT BMC for all sites and they were strongly correlated at the distal femur and proximal tibia (r=0.846, p<0.01; r=0.879, p<0.01, respectively). The results suggest that the novel method for site-specific analysis of trabecular bone-rich regions in mice via DXA yields more precise, accurate, and repeatable BMD measurements than the conventional method. PMID:26956416

  9. The health-care manager's guide to managing change in challenging times.

    Science.gov (United States)

    Lombardi, D N

    1996-01-01

    Fifteen years ago, Bill Gates was a college dropout working for a four-member, fledgling company in New Mexico. Today, he is the richest man in America and the head of perhaps the most powerful company in recent corporate history. Ten years ago, managed health care was merely a concept discussed in academic and industry observer circles. Now it is a norm in almost every health-care organization nationally. Five years ago, health-care professionals in every discipline believed the maxim that, ¿as long as people get sick, health-care professionals will have jobs.¿ In 1995, health-care executives have alternately referred to the widescale process of laying off employees as reengineering, rightsizing, downsizing, or RIF (reduction in force). With this massive amount of change, both societally and professionally, health-care managers have been contending with the change management process. Although a breadth of concepts borrowed from other industries and a plethora of conceptual practicums have entered the health-care educational realm, a straightforward, immediately useful approach to managing change is probably more beneficial, as the need to manage change quickly and effectively becomes the paramount criterion for health-care management success in the second half of this decade of change. In this article we will explore the four areas where mistakes are made most frequently by leaders in the change process, and we will provide specific strategies to not only avoid these mistakes but moreover reduce resistance to change, activate positive action, and ultimately improve performance through optimum staff contribution. The four critical areas we will explore are the reasons for resistance to change, the management of the proactive phase of change, creating staff interdependence, and key leadership roles for change management. PMID:10154378

  10. Advances of Precise Radiotherapy for Lung Cancer

    Directory of Open Access Journals (Sweden)

    Xin WANG

    2011-11-01

    Full Text Available At present lung tumor radiation therapy has entered the accurate radiotherapy era. Precise radiotherapy includes intensity modulated radiotherapy (IMRT, image-guided radiotherapy (IGRT and stereotactic body radiotherapy (SBRT. During the process of implementing precise radiotherapy, these problems should be fully considered to ensure executing precise radiotherapy accurately: patient positioning, controlling of the lung tumor motion, selecting of image techniques, PTV margin, dose prescription and reporting, arrangement of beams, controlling of dose volume and treatment delivering.

  11. Computed Tomography Number Changes Observed During Computed Tomography–Guided Radiation Therapy for Head and Neck Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Feng, Mei [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin (United States); Department of Radiation Oncology, Sichuan Cancer Hospital, Chengdu (China); Yang, Cungeng; Chen, Xiaojian; Xu, Shouping; Moraru, Ion [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin (United States); Lang, Jinyi [Department of Radiation Oncology, Sichuan Cancer Hospital, Chengdu (China); Schultz, Christopher [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin (United States); Li, X. Allen, E-mail: ali@mcw.edu [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin (United States)

    2015-04-01

    Purpose: To investigate CT number (CTN) changes in gross tumor volume (GTV) and organ at risk (OAR) according to daily diagnostic-quality CT acquired during CT-guided intensity modulated radiation therapy for head and neck cancer (HNC) patients. Methods and Materials: Computed tomography scans acquired using a CT-on-rails during daily CT-guided intensity modulated radiation therapy for 15 patients with stage II to IVa squamous cell carcinoma of the head and neck were analyzed. The GTV, parotid glands, spinal cord, and nonspecified tissue were generated on each selected daily CT. The changes in CTN distributions and the mean and mode values were collected. Pearson analysis was used to assess the correlation between the CTN change, organ volume reduction, and delivered radiation dose. Results: Volume and CTN changes for GTV and parotid glands can be observed during radiation therapy delivery for HNC. The mean (±SD) CTNs in GTV and ipsi- and contralateral parotid glands were reduced by 6 ± 10, 8 ± 7, and 11 ± 10 Hounsfield units, respectively, for all patients studied. The mean CTN changes in both spinal cord and nonspecified tissue were almost invisible (<2 Hounsfield units). For 2 patients studied, the absolute mean CTN changes in GTV and parotid glands were strongly correlated with the dose delivered (P<.001 and P<.05, respectively). For the correlation between CTN reductions and delivered isodose bins for parotid glands, the Pearson coefficient varied from −0.98 (P<.001) in regions with low-dose bins to 0.96 (P<.001) in high-dose bins and were patient specific. Conclusions: The CTN can be reduced in tumor and parotid glands during the course of radiation therapy for HNC. There was a fair correlation between CTN reduction and radiation doses for a subset of patients, whereas the correlation between CTN reductions and volume reductions in GTV and parotid glands were weak. More studies are needed to understand the mechanism for the radiation-induced CTN changes.

  12. Computed Tomography Number Changes Observed During Computed Tomography–Guided Radiation Therapy for Head and Neck Cancer

    International Nuclear Information System (INIS)

    Purpose: To investigate CT number (CTN) changes in gross tumor volume (GTV) and organ at risk (OAR) according to daily diagnostic-quality CT acquired during CT-guided intensity modulated radiation therapy for head and neck cancer (HNC) patients. Methods and Materials: Computed tomography scans acquired using a CT-on-rails during daily CT-guided intensity modulated radiation therapy for 15 patients with stage II to IVa squamous cell carcinoma of the head and neck were analyzed. The GTV, parotid glands, spinal cord, and nonspecified tissue were generated on each selected daily CT. The changes in CTN distributions and the mean and mode values were collected. Pearson analysis was used to assess the correlation between the CTN change, organ volume reduction, and delivered radiation dose. Results: Volume and CTN changes for GTV and parotid glands can be observed during radiation therapy delivery for HNC. The mean (±SD) CTNs in GTV and ipsi- and contralateral parotid glands were reduced by 6 ± 10, 8 ± 7, and 11 ± 10 Hounsfield units, respectively, for all patients studied. The mean CTN changes in both spinal cord and nonspecified tissue were almost invisible (<2 Hounsfield units). For 2 patients studied, the absolute mean CTN changes in GTV and parotid glands were strongly correlated with the dose delivered (P<.001 and P<.05, respectively). For the correlation between CTN reductions and delivered isodose bins for parotid glands, the Pearson coefficient varied from −0.98 (P<.001) in regions with low-dose bins to 0.96 (P<.001) in high-dose bins and were patient specific. Conclusions: The CTN can be reduced in tumor and parotid glands during the course of radiation therapy for HNC. There was a fair correlation between CTN reduction and radiation doses for a subset of patients, whereas the correlation between CTN reductions and volume reductions in GTV and parotid glands were weak. More studies are needed to understand the mechanism for the radiation-induced CTN changes

  13. Limited proteolysis and peptide mapping for comparability of biopharmaceuticals: An evaluation of repeatability, intra-assay precision and capability to detect structural change.

    Science.gov (United States)

    Perrin, Camille; Burkitt, Will; Perraud, Xavier; O'Hara, John; Jone, Carl

    2016-05-10

    The use of limited proteolysis followed by peptide mapping for the comparability of the higher-order structure of biopharmaceuticals was investigated. In this approach the proteolysis is performed under non-reducing and non-denaturing conditions, and the resulting peptide map is determined by the samples primary and higher order structures. This allows comparability of biopharmaceuticals to be made in terms of their higher order structure, using a method that is relatively simple to implement. The digestion of a monoclonal antibody under non-denaturing conditions was analyzed using peptide mapping, circular dichroism (CD) and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). This allowed an optimal digestion time to be chosen. This method was then assessed for its ability to detect structural change using a monoclonal antibody, which had been subjected to a range of stresses; deglycosylation, mild denaturation and a batch that had failed specifications due to in-process reduction. The repeatability and inter-assay precision were assessed. It was demonstrated that the limited proteolysis peptide maps of the three stressed samples were significantly different to control samples and that the differences observed were consistent between the occasions when the assays were run. A combination of limited proteolysis and CD or SDS-PAGE analysis was shown to enhance the capacity of these techniques to detect structural change, which otherwise would not have been observed. PMID:26918895

  14. Are Modic changes related to outcomes in lumbar disc herniation patients treated with imaging-guided lumbar nerve root blocks?

    International Nuclear Information System (INIS)

    Objective: To compare outcomes after imaging-guided transforaminal lumbar nerve root blocks in MRI confirmed symptomatic disc herniation patients with and without Modic changes (MC). Methods: Consecutive adult patients with MRI confirmed symptomatic lumbar disc herniations and an imaging-guided lumbar nerve root block injection who returned an outcomes questionnaire are included. Numerical rating scale (NRS) pain data was collected prior to injection and 20–30 min after injection. NRS and overall improvement were assessed using the patient's global impression of change (PGIC) scale at 1 day, 1 week and 1 month post injection. The proportion of patients with and without MC on MRI as well as Modic I and Modic II was calculated. These groups were compared for clinically relevant ‘improvement’ using the Chi-squared test. Baseline and follow-up NRS scores were compared for the groups using the unpaired t-test. Results: 346 patients are included with MC present in 57%. A higher percentage of patients without MC reported ‘improvement’ and a higher percentage of patients with MC reported ‘worsening’ but this did not reach statistical significance. The numerical scores on the PGIC and NRS scales showed that patients with MC had significantly higher pain and worse overall improvement scores at 1 month (p = 0.048 and p = 0.03) and a significantly lower 1 month NRS change score (p = 0.04). Conclusions: Patients with MRI confirmed symptomatic lumbar disc herniations and MC report significantly lower levels of pain reduction after a lumbar nerve root block compared to patients without MC

  15. Are Modic changes related to outcomes in lumbar disc herniation patients treated with imaging-guided lumbar nerve root blocks?

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, Cynthia K., E-mail: cynthia.peterson@balgrist.ch [Department of Radiology, Orthopaedic University Hospital Balgrist, University of Zürich (Switzerland); Pfirrmann, Christian W.A. [Department of Radiology, Orthopaedic University Hospital Balgrist, University of Zürich (Switzerland); Hodler, Jürg [Department of Radiology, University Hospital, University of Zürich (Switzerland)

    2014-10-15

    Objective: To compare outcomes after imaging-guided transforaminal lumbar nerve root blocks in MRI confirmed symptomatic disc herniation patients with and without Modic changes (MC). Methods: Consecutive adult patients with MRI confirmed symptomatic lumbar disc herniations and an imaging-guided lumbar nerve root block injection who returned an outcomes questionnaire are included. Numerical rating scale (NRS) pain data was collected prior to injection and 20–30 min after injection. NRS and overall improvement were assessed using the patient's global impression of change (PGIC) scale at 1 day, 1 week and 1 month post injection. The proportion of patients with and without MC on MRI as well as Modic I and Modic II was calculated. These groups were compared for clinically relevant ‘improvement’ using the Chi-squared test. Baseline and follow-up NRS scores were compared for the groups using the unpaired t-test. Results: 346 patients are included with MC present in 57%. A higher percentage of patients without MC reported ‘improvement’ and a higher percentage of patients with MC reported ‘worsening’ but this did not reach statistical significance. The numerical scores on the PGIC and NRS scales showed that patients with MC had significantly higher pain and worse overall improvement scores at 1 month (p = 0.048 and p = 0.03) and a significantly lower 1 month NRS change score (p = 0.04). Conclusions: Patients with MRI confirmed symptomatic lumbar disc herniations and MC report significantly lower levels of pain reduction after a lumbar nerve root block compared to patients without MC.

  16. Architecture in a climate of change: a guide to sustainable design

    International Nuclear Information System (INIS)

    The author calls for changes in the way we build. For change to be widely accepted there have to be convincing reasons why long established practices should be replaced. In the first part of the book he sets out those reasons by arguing that there is convincing evidence that climate changes now under way are primarily due to human activity in releasing carbon dioxide into the atmosphere. Buildings are particularly implicated in this process and so it is appropriate that the design and construction process should be a prime target in the war against catastrophic climate change. The book is designed to promote a creative partnership between the professions to produce buildings which achieve optimum conditions for their inhabitants whilst making minimum demands on fossil based energy. (author)

  17. Preface: Monitoring and modelling to guide coastal adaptation to extreme storm events in a changing climate

    OpenAIRE

    J M Brown; Ciavola, P.; Masselink, G.; McCall, R.; Plater, A.J.

    2016-01-01

    Storms across the globe and their associated consequences in coastal zones (flooding and erosion), combined with the long-term geomorphic evolution of our coastlines, are a threat to life and assets, both socioeconomic and environmental. In a changing climate, with a rising global sea level, potentially changing patterns in storm tracks and storminess, and rising population density and pressures on the coastal zone, the future risk of coastal storm impacts is likely to incre...

  18. Upending the social ecological model to guide health promotion efforts toward policy and environmental change.

    Science.gov (United States)

    Golden, Shelley D; McLeroy, Kenneth R; Green, Lawrence W; Earp, Jo Anne L; Lieberman, Lisa D

    2015-04-01

    Efforts to change policies and the environments in which people live, work, and play have gained increasing attention over the past several decades. Yet health promotion frameworks that illustrate the complex processes that produce health-enhancing structural changes are limited. Building on the experiences of health educators, community activists, and community-based researchers described in this supplement and elsewhere, as well as several political, social, and behavioral science theories, we propose a new framework to organize our thinking about producing policy, environmental, and other structural changes. We build on the social ecological model, a framework widely employed in public health research and practice, by turning it inside out, placing health-related and other social policies and environments at the center, and conceptualizing the ways in which individuals, their social networks, and organized groups produce a community context that fosters healthy policy and environmental development. We conclude by describing how health promotion practitioners and researchers can foster structural change by (1) conveying the health and social relevance of policy and environmental change initiatives, (2) building partnerships to support them, and (3) promoting more equitable distributions of the resources necessary for people to meet their daily needs, control their lives, and freely participate in the public sphere. PMID:25829123

  19. Development of Regulatory Guide for Risk-Informed Tech. Spec. Changes

    International Nuclear Information System (INIS)

    The policy statement on nuclear safety in 1994 encourages use of probabilistic safety assessment (PSA) for integrated safety evaluation and implementation of risk-informed regulation (RIR) for improving regulatory efficiency. RIR is to use PSA results and other risk insights in regulatory decision-making on the licensing basis change. Korea Institute of Nuclear Safety (KINS) developed the implementation plan and principles of RIR in response to the policy statement. One activity under way is to use PSA in support of decisions to modify an individual plant's technical specifications (TS). TS contain the items in the following specific categories: safety limit and limiting safety system settings, limiting conditions for operation, surveillance requirements, design features, and administrative controls. Typically the proposed risk-informed change to TS involves an extension of allowed outage time (AOT) or surveillance test interval (STI). There are many applications for TS change of which review is completed or under way

  20. Shared Governance in Times of Change: A Practical Guide for Universities and Colleges

    Science.gov (United States)

    Bahls, Steven S.

    2014-01-01

    Today's challenging higher education environment demands a new way of making decisions. Changing business models and methodologies for delivering academic programs present new opportunities (as well as risks) and call for innovative responses. This publication aims to "reboot" dialogues among boards, presidents, and faculties. It creates…

  1. High Sequestration, Low Emission, Food Secure Farming. Organic Agriculture - a Guide to Climate Change & Food Security

    OpenAIRE

    Jordan, Robert; Müller, Adrian; Oudes, Anne

    2009-01-01

    - affordable high sequestration practices based on local resources - enables continuous farmer-based adaptation to climate change - ideal for the improvement of the world’s 400 million smallholder farms - locally adapted, affordable and people centered - empowers local communities - established practices, systems and markets - experience, practices and expertise to share

  2. Tumor and normal tissue dosimetry changes during MR-guided pulsed-dose-rate (PDR) brachytherapy for cervical cancer

    International Nuclear Information System (INIS)

    Background and purpose: To analyze systematic changes in tumor and normal tissue anatomy and dosimetry using serial MR imaging during pulsed dose rate brachytherapy (PDR BT) for cervical cancer. Material and methods: Forty-three patients with cervical cancer underwent MR-guided PDR BT using an intrauterine applicator alone after external beam radiotherapy. MR imaging was repeated on days 2 and 3 of treatment and the day 1 plan was applied to the re-contoured volumes. Results: The mean uterine volume and mean HR CTV increased during treatment. This resulted in a decrease in the mean HR CTV D90 relative to the day 1 planned dose. There was no change in the mean bladder volume during treatment but the mean rectal volume increased. This correlated with an increase in the mean rectal dose. There were four local recurrences. There was no apparent relationship between either the planned or the delivered HR CTV D90 and local recurrence. There was only one case of late bladder toxicity but nine patients developed late rectal toxicity. The cumulative rectal dose during treatment was a better predictor of late rectal toxicity than the planned dose. Conclusions: Significant changes in tumor and normal tissue anatomy and dosimetry can occur during PDR BT and should be tracked and corrected using serial imaging and plan adaptation, especially when the day 1 tumor or normal tissue doses are close to the planning constraints

  3. Opening science the evolving guide on how the Internet is changing research, collaboration and scholarly publishing

    CERN Document Server

    Friesike, Sascha

    2014-01-01

    Modern information and communication technologies, together with a cultural upheaval within the research community, have profoundly changed research in nearly every aspect. Ranging from sharing and discussing ideas in social networks for scientists to new collaborative environments and novel publication formats, knowledge creation and dissemination as we know it is experiencing a vigorous shift towards increased transparency, collaboration and accessibility. Many assume that research workflows will change more in the next 20 years than they have in the last 200. This book provides researchers, decision makers, and other scientific stakeholders with a snapshot of the basics, the tools, and the underlying visions that drive the current scientific (r)evolution, often called ‘Open Science.’

  4. Guide to the Changes between the 2009 and 2012 International Energy Conservation Code

    Energy Technology Data Exchange (ETDEWEB)

    Mapes, Terry S.; Conover, David R.

    2012-05-31

    The International Code Council (ICC) published the 2012 International Energy Conservation Code{reg_sign} (IECC) in early 2012. The 2012 IECC is based on revisions, additions, and deletions to the 2009 IECC that were considered during the ICC code development process conducted in 2011. Solid vertical lines, arrows, or asterisks printed in the 2012 IECC indicate where revisions, deletions, or relocations of text respectively were made to 2009 IECC. Although these marginal markings indicate where changes have been made to the code, they do not provide any further guidance, leaving the reader to consult and compare the 2009 and 2012 IECC for more detail.

  5. Changes in disc herniation after CT-guided Percutaneous Laser Disc Decompression (PLDD): MR findings

    Science.gov (United States)

    Brat, Hugues G.; Bouziane, Tarik; Lambert, Jean; Divano, Luisa

    2004-09-01

    The aim of Percutaneous Laser Disc Decompression (PLDD) is to vaporize a small portion of the nucleus pulposus. Clinical efficacy of this technique is largely proven. However, time-evolution of intervertebral disc and its hernia after PLDD is not known. This study analyses changes in disc herniation and its native intervertebral disc at a mean follow-up of 7.5 months after PLDD in asymptomatic patients. Main observations at MRI are appearance of a high signal on T2WI in the hernia in 59%, shrinking of the hernia in 66% and overall stability of disc height.

  6. Interfractional change of high-risk CTV D90 during image-guided brachytherapy for uterine cervical cancer

    International Nuclear Information System (INIS)

    The purpose of this study was to evaluate interfractional changes of the minimum dose delivered to 90% of the high-risk clinical target volume (HR-CTV D90) and D2cc of the bladder and rectum during brachytherapy for uterine cervical cancer patients. A total of 52 patients received external beam radiotherapy and high-dose-rate intracavitary brachytherapy (ICBT). For each of four ICBT applications, a pelvic CT scan was performed and the HR-CTV was delineated. Retrospectively, these patients were divided into two groups: (1) the standard dose group with 6 Gy to point A in each ICBT, and (2) the adaptive dose group with a modified dose to point A to cover the HR-CTV with the 6-Gy isodose line as much as possible. The HR-CTV D90 was assessed in every session, and analyzed as interfractional changes. In the standard dose group, the interfractional changes of the HR-CTV D90 showed a linear increase from the first to the third of the four ICBT (average 6.1, 6.6, 7.0 and 7.1 Gy, respectively). In contrast, those of the adaptive dose group remained almost constant (average 7.2, 7.2, 7.3 and 7.4 Gy, respectively). Especially, in the case of a large HR-CTV volume (≥35 cm3) at first ICBT, the total HR-CTV D90 of the adaptive dose group with brachytherapy was significantly higher than that of the standard dose group. There were no significant differences in total D2cc in bladder and rectum between the two groups. Image-guided adaptive brachytherapy based on interfractional tumor volume change improves the dose to the HR-CTV while keeping rectal and bladder doses within acceptable levels. (author)

  7. Interfractional change of high-risk CTV D90 during image-guided brachytherapy for uterine cervical cancer.

    Science.gov (United States)

    Ohkubo, Yu; Ohno, Tatsuya; Noda, Shin-ei; Kubo, Nobuteru; Nakagawa, Akiko; Kawahara, Masahiro; Abe, Takanori; Kiyohara, Hiroki; Wakatsuki, Masaru; Nakano, Takashi

    2013-11-01

    The purpose of this study was to evaluate interfractional changes of the minimum dose delivered to 90% of the high-risk clinical target volume (HR-CTV D90) and D2cc of the bladder and rectum during brachytherapy for uterine cervical cancer patients. A total of 52 patients received external beam radiotherapy and high-dose-rate intracavitary brachytherapy (ICBT). For each of four ICBT applications, a pelvic CT scan was performed and the HR-CTV was delineated. Retrospectively, these patients were divided into two groups: (i) the standard dose group with 6 Gy to point A in each ICBT, and (ii) the adaptive dose group with a modified dose to point A to cover the HR-CTV with the 6-Gy isodose line as much as possible. The HR-CTV D90 was assessed in every session, and analyzed as interfractional changes. In the standard dose group, the interfractional changes of the HR-CTV D90 showed a linear increase from the first to the third of the four ICBT (average 6.1, 6.6, 7.0 and 7.1 Gy, respectively). In contrast, those of the adaptive dose group remained almost constant (average 7.2, 7.2, 7.3 and 7.4 Gy, respectively). Especially, in the case of a large HR-CTV volume (≥35 cm(3)) at first ICBT, the total HR-CTV D90 of the adaptive dose group with brachytherapy was significantly higher than that of the standard dose group. There were no significant differences in total D2cc in bladder and rectum between the two groups. Image-guided adaptive brachytherapy based on interfractional tumor volume change improves the dose to the HR-CTV while keeping rectal and bladder doses within acceptable levels. PMID:23732770

  8. Using the gradient of human cortical bone properties to determine age-related bone changes via ultrasonic guided waves.

    Science.gov (United States)

    Baron, Cécile

    2012-06-01

    Bone fragility depends not only on bone mass but also on bone quality (structure and material). To accurately evaluate fracture risk or propose therapeutic treatment, clinicians need a criterion, which reflects the determinants of bone strength: geometry, structure and material. In human long bone, the changes due to aging, accentuated by osteoporosis are often revealed through the trabecularization of cortical bone, i.e., increased porosity of endosteal bone inducing a thinning of the cortex. Consequently, the intracortical porosity gradient corresponding to the spatial variation in porosity across the cortical thickness is representative of loss of mass, changes in geometry (thinning) and variations in structure (porosity). This article examines the gradient of material properties and its age-related evolution as a relevant parameter to assess bone geometry, structure and material. By applying a homogenization process, cortical bone can be considered as an anisotropic functionally graded material with variations in material properties. A semi-analytical method based on the sextic Stroh formalism is proposed to solve the wave equation in an anisotropic functionally graded waveguide for two geometries, a plate and a tube, without using a multilayered model to represent the structure. This method provides an analytical solution called the matricant and explicitly expressed under the Peano series expansion form. Our findings indicate that ultrasonic guided waves are sensitive to the age-related evolution of realistic gradients in human bone properties across the cortical thickness and have their place in a multimodal clinical protocol. PMID:22502890

  9. Expert Guide

    DEFF Research Database (Denmark)

    Heiselberg, Per

    that dynamically respond to changes in climate and user demands, the report describes building concepts, design methods and tools that have been tested in theory and practice in buildings around the world. This guide is aimed at designers and consultants and describes the principles of responsive building concepts...

  10. EDITORIAL: Precision proteins Precision proteins

    Science.gov (United States)

    Demming, Anna

    2010-06-01

    Since the birth of modern day medicine, during the times of Hippocrates in ancient Greece, the profession has developed from the rudimentary classification of disease into a rigorous science with an inspiring capability to treat and cure. Scientific methodology has distilled clinical diagnostic tools from the early arts of prognosis, which used to rely as much on revelation and prophecy, as intuition and judgement [1]. Over the past decade, research into the interactions between proteins and nanosystems has provided some ingenious and apt techniques for delving into the intricacies of anatomical systems. In vivo biosensing has emerged as a vibrant field of research, as much of medical diagnosis relies on the detection of substances or an imbalance in the chemicals in the body. The inherent properties of nanoscale structures, such as cantilevers, make them well suited to biosensing applications that demand the detection of molecules at very low concentrations. Measurable deflections in cantilevers functionalised with antibodies provide quantitative indicators of the presence of specific antigens when the two react. Such developments have roused mounting interest in the interactions of proteins with nanostructures, such as carbon nanotubes [3], which have demonstrated great potential as generic biomarkers. Plasmonic properties are also being exploited in sensing applications, such as the molecular sentinel recently devised by researchers in the US. The device uses the plasmonic properties of a silver nanoparticle linked to a Raman labelled hairpin DNA probe to signal changes in the probe geometry resulting from interactions with substances in the environment. Success stories so far include the detection of two specific genes associated with breast cancer [4]. A greater understanding of how RNA interference regulates gene expression has highlighted the potential of using this natural process as another agent for combating disease in personalized medicine. However, the

  11. Improving Independent Student Navigation of Complex Educational Web Sites: An Analysis of Two Navigation Design Changes in LibGuides

    OpenAIRE

    Pittsley, Kate A; Memmott, Sara

    2012-01-01

    Can the navigation of complex research web sites be improved so that users more often find their way without intermediation or instruction?  Librarians at Eastern Michigan University discovered that students were not recognizing navigational elements on web based research guides and tested possible solutions. In this study, two types of navigation improvements were applied to separate sets of online guides. Both sets of experimental guides showed an increase in use of navigation to secondary ...

  12. Understanding groundwater – students' pre-conceptions and conceptual change by a theory-guided multimedia learning program

    Directory of Open Access Journals (Sweden)

    U. Unterbruner

    2015-11-01

    Full Text Available Groundwater is a crucial topic in education for sustainable development. Nevertheless, international studies with students of different ages have shown that the basic hydrogeological concept of groundwater defined as water within porous and permeable rocks is not an established everyday notion. Building upon international research a multimedia learning program ("Between the raincloud and the tap" was developed. Insights from the fields of conceptual change research, multimedia research, and the Model of Educational Reconstruction were specifically implemented. Two studies were conducted with Austrian pupils (7th grade and teacher training students from the fields of biology and geography in order to ascertain the effectiveness of the learning program. Using a quasi-experimental research design, the participants' conceptions and knowledge regarding groundwater were determined in a pre- and post-test. The pupils and students greatly profited from independently working through the learning software. Their knowledge of groundwater increased significantly compared to the control group and there was a highly significant increase in the number of scientifically correct notions of groundwater. The acceptance of the program was also generally very high. The results speak for the fact that theory-guided multimedia learning programs can play an important role in the transfer of research results into the classroom, particularly in science education.

  13. Understanding groundwater - students' pre-conceptions and conceptual change by a theory-guided multimedia learning program

    Science.gov (United States)

    Unterbruner, U.; Hilberg, S.; Schiffl, I.

    2015-11-01

    Groundwater is a crucial topic in education for sustainable development. Nevertheless, international studies with students of different ages have shown that the basic hydrogeological concept of groundwater defined as water within porous and permeable rocks is not an established everyday notion. Building upon international research a multimedia learning program ("Between the raincloud and the tap") was developed. Insights from the fields of conceptual change research, multimedia research, and the Model of Educational Reconstruction were specifically implemented. Two studies were conducted with Austrian pupils (7th grade) and teacher training students from the fields of biology and geography in order to ascertain the effectiveness of the learning program. Using a quasi-experimental research design, the participants' conceptions and knowledge regarding groundwater were determined in a pre- and post-test. The pupils and students greatly profited from independently working through the learning software. Their knowledge of groundwater increased significantly compared to the control group and there was a highly significant increase in the number of scientifically correct notions of groundwater. The acceptance of the program was also generally very high. The results speak for the fact that theory-guided multimedia learning programs can play an important role in the transfer of research results into the classroom, particularly in science education.

  14. Understanding groundwater - students' pre-conceptions and conceptual change by means of a theory-guided multimedia learning program

    Science.gov (United States)

    Unterbruner, Ulrike; Hilberg, Sylke; Schiffl, Iris

    2016-06-01

    Education on the subject of groundwater is crucial for sustainability. Nevertheless, international studies with students across different age groups have shown that the basic hydrogeological concept of groundwater defined as water within porous and permeable rocks is not an established everyday notion. Drawing from international research, a multimedia learning program Zwischen Regenwolke und Wasserhahn (between the rain cloud and the tap) was developed, which incorporates specific insights from the fields of conceptual change research, multimedia research, and the model of educational reconstruction. The effectiveness of the learning program was ascertained by means of two studies with Austrian seventh grade pupils as well as teacher-training students from the fields of biology and geography in order to ascertain the effectiveness of the learning program. Using a quasi-experimental research design, the participants' conceptions and knowledge of groundwater were determined in a pre- and post-test. The pupils and students greatly benefitted from working through the learning software independently. Their knowledge of groundwater increased significantly compared to the control group and there was a highly significant increase in the number of scientifically correct notions of groundwater. The acceptance of the program was also generally very high. The results indicate that theory-guided multimedia learning programs can play an important role in the transfer of research results to classroom settings, especially in science education.

  15. Guide to Behavior Change

    Science.gov (United States)

    ... long-term challenge. Weight can affect a person's self-esteem. Excess weight is highly visible and evokes some ... Skip footer links and go to content Twitter Facebook YouTube Google+ SEARCH | SITE INDEX | ACCESSIBILITY | PRIVACY STATEMENT | ...

  16. Corneal changes following collagen cross linking and simultaneous topography guided photoablation with collagen cross linking for keratoconus

    Directory of Open Access Journals (Sweden)

    Prema Padmanabhan

    2014-01-01

    Full Text Available Purpose: To compare the outcome of Collagen cross-linking (CXL with that following topography-guided customized ablation treatment (T-CAT with simultaneous CXL in eyes with progressive keratoconus. Materials and Methods: This was a prospective, non-randomized single centre study of 66 eyes with progressive keratoconus. Of these, 40 eyes underwent CXL and 26 eyes underwent T-CAT + CXL. The refractive, topographic, tomographic and aberrometric changes measured at baseline, 1, 3 and 6 months post-operatively were compared between both groups. Results: After a mean follow-up of 7.7 ± 1.3 months, the mean retinoscopic cylinder decreased by 1.02 ± 3.16 D in the CXL group ( P = 0.1 and 2.87 ± 3.22 D in the T-CAT + CXL group ( P = 0.04. The Best corrected visual acuity increased by 2 lines or more in 10% of eyes in the CXL group and in 23.3% of eyes in the T-CAT + CXL group. The mean steepest-K reduced by 0.40 ± 3.71 D ( P = 0.77 in the CXL group and by 2.91 ± 2.01D ( P = 0.03 in the T-CAT + CXL group. The sag factor and surface asymmetry index showed no significant change in the CXL group but reduced by 3.59 ± 5.94 D ( P = 0.01 and 0.72 ± 1.18 ( P = 0.02 respectively in the T-CAT + CXL group. There was a significant increase in the highest posterior corneal elevation in both groups (9.57 ± 14.93 μ in the CXL group and 7.85 ± 9.25 μ in the T-CAT + CXL group, P ≤ 0.001 for both. There was significantly greater reduction of mean coma ( P < 0.001 and mean higher-order aberrations ( P = 0.01 following T-CAT + CXL compared to CXL. Conclusions: CAT + CXL is an effective approach to confer biomechanical stability and to improve the corneal contour in eyes with keratoconus and results in better refractive, topographic and aberrometric outcomes than CXL alone.

  17. Land cover change detection using a GIS-guided, feature-based classification of Landsat thematic mapper data. [Geographic Information System

    Science.gov (United States)

    Enslin, William R.; Ton, Jezching; Jain, Anil

    1987-01-01

    Landsat TM data were combined with land cover and planimetric data layers contained in the State of Michigan's geographic information system (GIS) to identify changes in forestlands, specifically new oil/gas wells. A GIS-guided feature-based classification method was developed. The regions extracted by the best image band/operator combination were studied using a set of rules based on the characteristics of the GIS oil/gas pads.

  18. Versatile module for experiments with focussing neutron guides

    Energy Technology Data Exchange (ETDEWEB)

    Adams, T.; Pfleiderer, C.; Böni, P. [Physik-Department, Technische Universität München, D-85748 Garching (Germany); Brandl, G.; Chacon, A.; Wagner, J. N.; Rahn, M.; Mühlbauer, S.; Georgii, R. [Physik-Department, Technische Universität München, D-85748 Garching (Germany); Heinz Maier-Leibnitz Zentrum, FRM II, Technische Universität München, D-85748 Garching (Germany)

    2014-09-22

    We report the development of a versatile module that permits fast and reliable use of focussing neutron guides under varying scattering angles. A simple procedure for setting up the module and neutron guides is illustrated by typical intensity patterns to highlight operational aspects as well as typical parasitic artefacts. Combining a high-precision alignment table with separate housings for the neutron guides on kinematic mounts, the change-over between neutron guides with different focussing characteristics requires no readjustments of the experimental setup. Exploiting substantial gain factors, we demonstrate the performance of this versatile neutron scattering module in a study of the effects of uniaxial stress on the domain populations in the transverse spin density wave phase of single crystal Cr.

  19. Versatile module for experiments with focussing neutron guides

    CERN Document Server

    Adams, T; Chacon, A; Wagner, J N; Rahn, M; Mühlbauer, S; Georgii, R; Pfleiderer, C; Böni, P

    2014-01-01

    We report the development of a versatile module that permits fast and reliable use of focussing neutron guides under varying scattering angles. A simple procedure for setting up the module and neutron guides is illustrated by typical intensity patterns to highlight operational aspects as well as typical parasitic artefacts. Combining a high-precision alignment table with separate housings for the neutron guides on kinematic mounts, the change-over between neutron guides with different focussing characteristics requires no readjustments of the experimental set-up. Exploiting substantial gain factors, we demonstrate the performance of this versatile neutron scattering module in a study of the effects of uniaxial stress on the domain populations in the transverse spin density wave phase of single crystal Cr.

  20. Precision agricultural systems

    Science.gov (United States)

    Precision agriculture is a new farming practice that has been developing since late 1980s. It has been variously referred to as precision farming, prescription farming, site-specific crop management, to name but a few. There are numerous definitions for precision agriculture, but the central concept...

  1. Neurotransmitter changes during interference task in anterior cingulate cortex: evidence from fMRI-guided functional MRS at 3 T.

    Science.gov (United States)

    Kühn, Simone; Schubert, Florian; Mekle, Ralf; Wenger, Elisabeth; Ittermann, Bernd; Lindenberger, Ulman; Gallinat, Jürgen

    2016-06-01

    Neural activity as indirectly observed in blood oxygenation level-dependent (BOLD) response is thought to reflect changes in neurotransmitter flux. In this study, we used fMRI-guided functional magnetic resonance spectroscopy (MRS) to measure metabolite/BOLD associations during a cognitive task at 3 T. GABA and glutamate concentration in anterior cingulate cortex (ACC) were determined by means of MRS using the SPECIAL pulse sequence before, during and after the performance of a manual Stroop task. MRS voxel positions were centred around individuals' BOLD activity during Stroop performance. Levels of GABA and glutamate showed inverted U-shape patterns across measurement time points (before, during, and after task), glutamine increased linearly and total creatine did not change. The GABA increase during task performance was associated with ACC BOLD signal changes in both congruent and incongruent Stroop conditions. Using an fMRI-guided MRS approach, an association between induced inhibitory neurotransmitter increase and BOLD changes was observed. The proposed procedure might allow the in vivo investigation of normal and dysfunctional associations between neurotransmitters and BOLD signal crucial for cerebral functioning. PMID:25976598

  2. GreyGuide, GreyNet’s web access portal and lobby for change in Grey Literature

    OpenAIRE

    Farace, Dominic J.; Frantzen, Jerry; Biagioni, Stefania; Carlesi, Carlo; Ponti, Roberto (ISTI-CNR); Stock, Christiane; GreyNet, Grey Literature Network Service

    2015-01-01

    In December 2013, the GreyGuide was formerly launched as an online forum and repository of good practice in grey literature. The project partners then turned to the acquisition of both proposed and published good practices. During this same timeframe, GreyNet – one of the project partners – welcomed far reaching developments in its infrastructure. Three new committees were established alongside its Program Committee in line with GreyNet’s fourfold mission dedicated to research, publication, o...

  3. Precision performance lamp technology

    Science.gov (United States)

    Bell, Dean A.; Kiesa, James E.; Dean, Raymond A.

    1997-09-01

    A principal function of a lamp is to produce light output with designated spectra, intensity, and/or geometric radiation patterns. The function of a precision performance lamp is to go beyond these parameters and into the precision repeatability of performance. All lamps are not equal. There are a variety of incandescent lamps, from the vacuum incandescent indictor lamp to the precision lamp of a blood analyzer. In the past the definition of a precision lamp was described in terms of wattage, light center length (LCL), filament position, and/or spot alignment. This paper presents a new view of precision lamps through the discussion of a new segment of lamp design, which we term precision performance lamps. The definition of precision performance lamps will include (must include) the factors of a precision lamp. But what makes a precision lamp a precision performance lamp is the manner in which the design factors of amperage, mscp (mean spherical candlepower), efficacy (lumens/watt), life, not considered individually but rather considered collectively. There is a statistical bias in a precision performance lamp for each of these factors; taken individually and as a whole. When properly considered the results can be dramatic to the system design engineer, system production manage and the system end-user. It can be shown that for the lamp user, the use of precision performance lamps can translate to: (1) ease of system design, (2) simplification of electronics, (3) superior signal to noise ratios, (4) higher manufacturing yields, (5) lower system costs, (6) better product performance. The factors mentioned above are described along with their interdependent relationships. It is statistically shown how the benefits listed above are achievable. Examples are provided to illustrate how proper attention to precision performance lamp characteristics actually aid in system product design and manufacturing to build and market more, market acceptable product products in the

  4. The newest precision measurement

    International Nuclear Information System (INIS)

    This book introduces basic of precision measurement, measurement of length, limit gauge, measurement of angles, measurement of surface roughness, measurement of shapes and locations, measurement of outline, measurement of external and internal thread, gear testing, accuracy inspection of machine tools, three dimension coordinate measuring machine, digitalisation of precision measurement, automation of precision measurement, measurement of cutting tools, measurement using laser, and point of choosing length measuring instrument.

  5. Precision Clock Evaluation Facility

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Tests and evaluates high-precision atomic clocks for spacecraft, ground, and mobile applications. Supports performance evaluation, environmental testing,...

  6. The Scheme and the Preliminary Test of Object-Oriented Simultaneous 3D Geometric and Physical Change Detection Using GIS-guided Knowledge

    Directory of Open Access Journals (Sweden)

    Chang LI

    2013-07-01

    Full Text Available Current methods of remotely sensed image change detection almost assume that the DEM of the surface objects do not change. However, for the geological disasters areas (such as: landslides, mudslides and avalanches, etc., this assumption does not hold. And the traditional approach is being challenged. Thus, a new theory for change detection needs to be extended from two-dimensional (2D to three-dimensional (3D urgently. This paper aims to present an innovative scheme for change detection method, object-oriented simultaneous three-dimensional geometric and physical change detection (OOS3DGPCD using GIS-guided knowledge. This aim will be reached by realizing the following specific objectives: a to develop a set of automatic multi-feature matching and registration methods; b to propose an approach for simultaneous detecting 3D geometric and physical attributes changes based on the object-oriented strategy; c to develop a quality control method for OOS3DGPCD; d to implement the newly proposed OOS3DGPCD method by designing algorithms and developing a prototype system. For aerial remotely sensed images of YingXiu, Wenchuan, preliminary experimental results of 3D change detection are shown so as to verify our approach.

  7. Assessing the beginning to end-of-mission sensitivity change of the PREcision MOnitor Sensor total solar irradiance radiometer (PREMOS/PICARD)

    Science.gov (United States)

    Ball, William T.; Schmutz, Werner; Fehlmann, André; Finsterle, Wolfgang; Walter, Benjamin

    2016-08-01

    The switching of the total solar irradiance (TSI) backup radiometer (PREMOS-B) to a primary role for 2 weeks at the end of the PICARD mission provides a unique opportunity to test the fundamental hypothesis of radiometer experiments in space, which is that the sensitivity change of instruments due to the space environment is identical for the same instrument type as a function of solar-exposure time of the instruments. We verify this hypothesis for the PREMOS TSI radiometers within the PREMOS experiment on the PICARD mission. We confirm that the sensitivity change of the backup instrument, PREMOS-B, is similar to that of the identically-constructed primary radiometer, PREMOS-A. The extended exposure of the backup instrument at the end of the mission allows for the assessment, with an uncertainty estimate, of the sensitivity change of the primary radiometer from the beginning of the PICARD mission compared to the end, and of the degradation of the backup over the mission. We correct six sets of PREMOS-B observations connecting October 2011 with February 2014, using six ratios from simultaneous PREMOS-A and PREMOS-B exposures during the first days of PREMOS-A operation in 2010. These ratios are then used, without indirect estimates or assumptions, to evaluate the stability of SORCE/TIM and SOHO/VIRGO TSI measurements, which have both operated for more than a decade and now show different trends over the time span of the PICARD mission, namely from 2010 to 2014. We find that by February 2014 relative to October 2011 PREMOS-B supports the SORCE/TIM TSI time evolution, which in May 2014 relative to October 2011 is ~0.11 W m-2, or ~84 ppm, higher than SOHO/VIRGO. Such a divergence between SORCE/TIM and SOHO/VIRGO over this period is a significant fraction of the estimated decline of 0.2 W m-2 between the solar minima of 1996 and 2008, and questions the reliability of that estimated trend. Extrapolating the uncertainty indicated by the disagreement of SORCE/TIM and PREMOS

  8. Assessing the beginning to end-of-mission sensitivity change of the PREcision MOnitor Sensor total solar irradiance radiometer (PREMOS/PICARD

    Directory of Open Access Journals (Sweden)

    Ball William T.

    2016-01-01

    Full Text Available The switching of the total solar irradiance (TSI backup radiometer (PREMOS-B to a primary role for 2 weeks at the end of the PICARD mission provides a unique opportunity to test the fundamental hypothesis of radiometer experiments in space, which is that the sensitivity change of instruments due to the space environment is identical for the same instrument type as a function of solar-exposure time of the instruments. We verify this hypothesis for the PREMOS TSI radiometers within the PREMOS experiment on the PICARD mission. We confirm that the sensitivity change of the backup instrument, PREMOS-B, is similar to that of the identically-constructed primary radiometer, PREMOS-A. The extended exposure of the backup instrument at the end of the mission allows for the assessment, with an uncertainty estimate, of the sensitivity change of the primary radiometer from the beginning of the PICARD mission compared to the end, and of the degradation of the backup over the mission. We correct six sets of PREMOS-B observations connecting October 2011 with February 2014, using six ratios from simultaneous PREMOS-A and PREMOS-B exposures during the first days of PREMOS-A operation in 2010. These ratios are then used, without indirect estimates or assumptions, to evaluate the stability of SORCE/TIM and SOHO/VIRGO TSI measurements, which have both operated for more than a decade and now show different trends over the time span of the PICARD mission, namely from 2010 to 2014. We find that by February 2014 relative to October 2011 PREMOS-B supports the SORCE/TIM TSI time evolution, which in May 2014 relative to October 2011 is ~0.11 W m−2, or ~84 ppm, higher than SOHO/VIRGO. Such a divergence between SORCE/TIM and SOHO/VIRGO over this period is a significant fraction of the estimated decline of 0.2 W m−2 between the solar minima of 1996 and 2008, and questions the reliability of that estimated trend. Extrapolating the uncertainty indicated by the

  9. Precision Attachment: Retained Overdenture

    OpenAIRE

    Jayasree, K; Mrs.M.Bharathi; Nag, V. Dileep; B. Vinod

    2011-01-01

    Precision attachments are small interlocking devices to connect prosthesis and abutments that offer a variety of solutions to the challenge of balance between functional stability and cosmetic appeal. Precision attachments have wide applications, used in fixed removable bridge, removable partial dentures, overdentures, implant retained overdentures, and maxillofacial prosthesis. Attachment retained overdentures helps in distribution of masticatory forces, minimizes trauma to abutments and sof...

  10. Precision machining commercialization

    International Nuclear Information System (INIS)

    To accelerate precision machining development so as to realize more of the potential savings within the next few years of known Department of Defense (DOD) part procurement, the Air Force Materials Laboratory (AFML) is sponsoring the Precision Machining Commercialization Project (PMC). PMC is part of the Tri-Service Precision Machine Tool Program of the DOD Manufacturing Technology Five-Year Plan. The technical resources supporting PMC are provided under sponsorship of the Department of Energy (DOE). The goal of PMC is to minimize precision machining development time and cost risk for interested vendors. PMC will do this by making available the high precision machining technology as developed in two DOE contractor facilities, the Lawrence Livermore Laboratory of the University of California and the Union Carbide Corporation, Nuclear Division, Y-12 Plant, at Oak Ridge, Tennessee

  11. BOOK REVIEWS - Precision agriculture

    Directory of Open Access Journals (Sweden)

    Stanisław Samborski

    2007-01-01

    Full Text Available Precision agriculture (PA is a term, which has recently become very popular in agronomy. In short this term means crop production based on site-specific crop management (SSCM. Precision agriculture is an integrated agricultural management system incorporating different science disciplines e.g. crop science, agricultural engineering and geostatistics. It also uses numerous tools i.e., geographic information system (GIS, Global Positioning System (GPS, remote sensing yield monitors. Because of the multidisciplinary character of precision agriculture, books published on this subject differ in their content. The first books on this topic appeared in the mid 90’ of the last century. The intention of this paper is to present reviews of three books the titles of which each contains the term “precision agriculture”. The books are as follows:1 Handbook of Precision Agriculture – Principles and Applications (2006 edited by Ancha Srinivasan. 2 Precision Agriculture’05 (2005 edited by John V. Stafford 3 Precision Agriculture (2006 by Terry A. Brasse.

  12. Precision oncology: origins, optimism, and potential.

    Science.gov (United States)

    Prasad, Vinay; Fojo, Tito; Brada, Michael

    2016-02-01

    Imatinib, the first and arguably the best targeted therapy, became the springboard for developing drugs aimed at molecular targets deemed crucial to tumours. As this development unfolded, a revolution in the speed and cost of genetic sequencing occurred. The result-an armamentarium of drugs and an array of molecular targets-set the stage for precision oncology, a hypothesis that cancer treatment could be markedly improved if therapies were guided by a tumour's genomic alterations. Drawing lessons from the biological basis of cancer and recent empirical investigations, we take a more measured view of precision oncology's promise. Ultimately, the promise is not our concern, but the threshold at which we declare success. We review reports of precision oncology alongside those of precision diagnostics and novel radiotherapy approaches. Although confirmatory evidence is scarce, these interventions have been widely endorsed. We conclude that the current path will probably not be successful or, at a minimum, will have to undergo substantive adjustments before it can be successful. For the sake of patients with cancer, we hope one form of precision oncology will deliver on its promise. However, until confirmatory studies are completed, precision oncology remains unproven, and as such, a hypothesis in need of rigorous testing. PMID:26868357

  13. Precision digital control systems

    Science.gov (United States)

    Vyskub, V. G.; Rozov, B. S.; Savelev, V. I.

    This book is concerned with the characteristics of digital control systems of great accuracy. A classification of such systems is considered along with aspects of stabilization, programmable control applications, digital tracking systems and servomechanisms, and precision systems for the control of a scanning laser beam. Other topics explored are related to systems of proportional control, linear devices and methods for increasing precision, approaches for further decreasing the response time in the case of high-speed operation, possibilities for the implementation of a logical control law, and methods for the study of precision digital control systems. A description is presented of precision automatic control systems which make use of electronic computers, taking into account the existing possibilities for an employment of computers in automatic control systems, approaches and studies required for including a computer in such control systems, and an analysis of the structure of automatic control systems with computers. Attention is also given to functional blocks in the considered systems.

  14. Precision Multiboson Phenomenology

    OpenAIRE

    Bozzi, G.; Campanario, F.; Englert, C.; Rauch, M.; Spannoswky, M.; Zeppenfeld, D.

    2012-01-01

    We present recent results in precision multiboson (+jet) phenomenology at the LHC. Results for diboson + jet, triboson, and also for WAA + jet will be discussed focusing on the impact of the perturbative corrections on the expected phenomenology.

  15. Laser precision microfabrication

    CERN Document Server

    Sugioka, Koji; Pique, Alberto

    2010-01-01

    Miniaturization and high precision are rapidly becoming a requirement for many industrial processes and products. As a result, there is greater interest in the use of laser microfabrication technology to achieve these goals. This book composed of 16 chapters covers all the topics of laser precision processing from fundamental aspects to industrial applications to both inorganic and biological materials. It reviews the sate of the art of research and technological development in the area of laser processing.

  16. BOOK REVIEWS - Precision agriculture

    OpenAIRE

    Stanisław Samborski; Dariusz Gozdowski

    2007-01-01

    Precision agriculture (PA) is a term, which has recently become very popular in agronomy. In short this term means crop production based on site-specific crop management (SSCM). Precision agriculture is an integrated agricultural management system incorporating different science disciplines e.g. crop science, agricultural engineering and geostatistics. It also uses numerous tools i.e., geographic information system (GIS), Global Positioning System (GPS), remote sensing yield monitors. Because...

  17. A field guide to real-time culture change: just "rolling out" a training program won't cut it.

    Science.gov (United States)

    Kusy, Mitchell; Holloway, Elizabeth L

    2014-01-01

    Presented as a representative case of how to handle the disruptive behaviors of professionals in healthcare, this article describes the strategies of a systems approach with a five-phase model for culture change. The "large-scale, real-time" culture change process, based on our own evidence-based research on toxic behaviors and the research of others, has been demonstrated to be more effective than one-on-one feedback to change these behaviors. The real-time approach has been applied to other organizational situations--strategy formulation, change management, or service improvement--with more sustainable effects than simply training alone. This article will help your organization with four outcomes: understanding the rationale for a five-phase model for cultural change, describing the advantages of a real-time versus nonreal-time approach to change, identifying the how-to's for application within a systems approach, and articulating a clear evaluation process to sustain successful organizational culture change. PMID:24873126

  18. Precision Cryogenic Dilatometer

    Science.gov (United States)

    Dudik, Matthew; Halverson, Peter; Levine-West, Marie; Marcin, Martin; Peters, Robert D.; Shaklan, Stuart

    2005-01-01

    A dilatometer based on a laser interferometer is being developed to measure mechanical creep and coefficients of thermal expansion (CTEs) of materials at temperatures ranging from ambient down to 15 K. This cryogenic dilatometer has been designed to minimize systematic errors that limit the best previously available dilatometers. At its prototype stage of development, this cryogenic dilatometer yields a strain measurement error of 35 ppb or 1.7 ppb/K CTE measurement error for a 20-K thermal load, for low-expansion materials in the temperature range from 310 down to 30 K. Planned further design refinements that include a provision for stabilization of the laser and addition of a high-precision sample-holding jig are expected to reduce the measurement error to 5-ppb strain error or 0.3-ppb/K CTE error for a 20-K thermal load. The dilatometer (see figure) includes a common-path, differential, heterodyne interferometer; a dual-frequency, stabilized source bench that serves as the light source for the interferometer; a cryogenic chamber in which one places the material sample to be studied; a cryogenic system for cooling the interior of the chamber to the measurement temperature; an ultra-stable alignment stage for positioning the chamber so that the sample is properly positioned with respect to the interferometer; and a data-acquisition and control system. The cryogenic chamber and the interferometer portion of the dilatometer are housed in a vacuum chamber on top of a vibration isolating optical table in a cleanroom. The sample consists of two pieces a pillar on a base both made of the same material. Using reflections of the interferometer beams from the base and the top of the pillar, what is measured is the change in length of the pillar as the temperature in the chamber is changed. In their fundamental optical and electronic principles of operation, the laser light source and the interferometer are similar to those described in Common-Path Heterodyne

  19. Preface to special issue: Monitoring and modelling to guide coastal adaptation to extreme storm events in a changing climate

    OpenAIRE

    J. Brown; Ciavola, P.; Masselink, G.; McCall, R.; Plater, A.

    2016-01-01

    Storms across the globe and their associated consequences in coastal zones (flooding and erosion), combined with the long-term geomorphic evolution of our coastlines, are a threat to life and assets, both socioeconomic and environmental. In a changing climate, with a rising global sea level, potentially changing patterns in storm tracks and storminess, and rising population density and pressures on the coastal zone, the future risk of coastal storm impacts is likely to increase. Coastal manag...

  20. Precise Object Tracking under Deformation

    International Nuclear Information System (INIS)

    The precise object tracking is an essential issue in several serious applications such as; robot vision, automated surveillance (civil and military), inspection, biomedical image analysis, video coding, motion segmentation, human-machine interface, visualization, medical imaging, traffic systems, satellite imaging etc. This framework focuses on the precise object tracking under deformation such as scaling, rotation, noise, blurring and change of illumination. This research is a trail to solve these serious problems in visual object tracking by which the quality of the overall system will be improved. Developing a three dimensional (3D) geometrical model to determine the current pose of an object and predict its future location based on FIR model learned by the OLS. This framework presents a robust ranging technique to track a visual target instead of the traditional expensive ranging sensors. The presented research work is applied to real video stream and achieved high precession results. xiiiThe precise object tracking is an essential issue in several serious applications such as; robot vision, automated surveillance (civil and military), inspection, biomedical image analysis, video coding, motion segmentation, human-machine interface, visualization, medical imaging, traffic systems, satellite imaging etc. This framework focuses on the precise object tracking under deformation such as scaling, rotation, noise, blurring and change of illumination. This research is a trail to solve these serious problems in visual object tracking by which the quality of the overall system will be improved. Developing a three dimensional (3D) geometrical model to determine the current pose of an object and predict its future location based on FIR model learned by the OLS. This framework presents a robust ranging technique to track a visual target instead of the traditional expensive ranging sensors. The presented research work is applied to real video stream and achieved high

  1. Modeling Climate Change and Ecosystem Response—Developing Tools to Guide Resource Management in the Southeastern U.S

    Science.gov (United States)

    Hughes, W. B.; Dalton, M.; Jones, S.

    2010-12-01

    Resource managers are at the forefront of a new era of management. They must consider the potential impacts of climate change on the Nation’s resources and proactively develop strategies for dealing with those impacts on terrestrial and aquatic ecosystems. This requires rigorous, scientific understanding of the interactions among the varying components of the atmospheric, hydrologic, terrestrial, and biological systems and the ability to predict future changes to these systems. The Southeast Regional Assessment Project (SERAP) is the first regional assessment by the USGS National Climate Change and Wildlife Science Center to analyze climate-change data and develop tools for assessing how changing conditions are likely to impact resources. The following six components are being developed for SERAP by an interdisciplinary team of USGS and University researchers: Climate Downscaling—Statistical downscaled climate models will provide information on long-term average changes and high-impact climate extremes that other team members need to assess regional change. Relative Sea-Level Rise—Probabilistic forecasts of sea-level rise along the Gulf Coast will incorporate parameters that affect land-surface elevation such as inundation, erosion, subsidence, and accretion. These and other new tools will assist resource managers to visualize areas most impacted by sea-level rise. Terrestrial Habitat Change—Regional climate models integrated with models of urbanization and vegetation dynamics will assess landscape change and its impact on bird species. Streamflow and Aquatic Ecosystems—A watershed model of the Apalachicola-Chatthoochee-Flint River Basin will simulate streamflow and water temperature conditions in response to future climate scenarios. Ecological models that incorporate these simulated streamflow and water-temperature changes will predict the distribution of fish and mussel species under altered conditions. Optimizing Conservation—Strategies for

  2. Estimating sparse precision matrices

    Science.gov (United States)

    Padmanabhan, Nikhil; White, Martin; Zhou, Harrison H.; O'Connell, Ross

    2016-05-01

    We apply a method recently introduced to the statistical literature to directly estimate the precision matrix from an ensemble of samples drawn from a corresponding Gaussian distribution. Motivated by the observation that cosmological precision matrices are often approximately sparse, the method allows one to exploit this sparsity of the precision matrix to more quickly converge to an asymptotic 1/√{N_sim} rate while simultaneously providing an error model for all of the terms. Such an estimate can be used as the starting point for further regularization efforts which can improve upon the 1/√{N_sim} limit above, and incorporating such additional steps is straightforward within this framework. We demonstrate the technique with toy models and with an example motivated by large-scale structure two-point analysis, showing significant improvements in the rate of convergence. For the large-scale structure example we find errors on the precision matrix which are factors of 5 smaller than for the sample precision matrix for thousands of simulations or, alternatively, convergence to the same error level with more than an order of magnitude fewer simulations.

  3. Precision Higgs Physics

    Science.gov (United States)

    Boughezal, Radja

    2015-04-01

    The future of the high energy physics program will increasingly rely upon precision studies looking for deviations from the Standard Model. Run I of the Large Hadron Collider (LHC) triumphantly discovered the long-awaited Higgs boson, and there is great hope in the particle physics community that this new state will open a portal onto a new theory of Nature at the smallest scales. A precision study of Higgs boson properties is needed in order to test whether this belief is true. New theoretical ideas and high-precision QCD tools are crucial to fulfill this goal. They become even more important as larger data sets from LHC Run II further reduce the experimental errors and theoretical uncertainties begin to dominate. In this talk, I will review recent progress in understanding Higgs properties,including the calculation of precision predictions needed to identify possible physics beyond the Standard Model in the Higgs sector. New ideas for measuring the Higgs couplings to light quarks as well as bounding the Higgs width in a model-independent way will be discussed. Precision predictions for Higgs production in association with jets and ongoing efforts to calculate the inclusive N3LO cross section will be reviewed.

  4. Guiding Age 10-11 Students to Notice the Salient Features of Physical Change Models in Chemistry Digital Learning Objects

    Science.gov (United States)

    Gustafson, Brenda; Mahaffy, Peter; Martin, Brian

    2015-01-01

    This paper focuses on one Grade 5 class (9 females; 9 males) who worked in student-pairs to view five digital learning object (DLO) lessons created by the authors and meant to introduce students to the nature of models, the particle nature of matter, and physical change. Specifically, the paper focuses on whether DLO design elements could assist…

  5. Developing Precision Stroke Imaging

    Directory of Open Access Journals (Sweden)

    DavidSLiebeskind

    2014-03-01

    Full Text Available Stroke experts stand at the cusp of a unique opportunity to advance the care of patients with cerebrovascular disorders across the globe through improved imaging approaches. NIH initiatives including the Stroke Progress Review Group (SPRG promotion of imaging in stroke research and the newly established NINDS Stroke Trials network converge with the rapidly evolving concept of precision medicine. Precision stroke imaging portends the coming shift to individualized approaches to cerebrovascular disorders where big data may be leveraged to identify and manage stroke risk with specific treatments utilizing an improved neuroimaging infrastructure, data collection and analysis. We outline key aspects of the stroke imaging field where precision medicine may rapidly transform the care of stroke patients in the next few years.

  6. Improving Precision of Types

    DEFF Research Database (Denmark)

    Winther, Johnni

    crucial to the quality of these automated checks, and in this thesis we present three different improvements to the precision of types in three different aspects of the Java programming language. First we show how to extend the type system in Java with a new type which enables the detection of unintended......Types in programming languages provide a powerful tool for the programmer to document the code so that a large aspect of the intent can not only be presented to fellow programmers but also be checked automatically by compilers. The precision with which types model the behavior of programs is...... mixing of unrelated types. Secondly, we present an improvement of the type checking algorithm in Java which enables the compiler to detect and ease the use of a common programming idiom called guarded casts. Thirdly, we present an improvement of the precision with which classes generated by a parser...

  7. Precision Muonium Spectroscopy

    CERN Document Server

    Jungmann, Klaus P

    2016-01-01

    The muonium atom is the purely leptonic bound state of a positive muon and an electron. It has a lifetime of 2.2 $\\mu$s. The absence of any known internal structure provides for precision experiments to test fundamental physics theories and to determine accurate values of fundamental constants. In particular groun dstate hyperfine structure transitions can be measured by microwave spectroscopy to deliver the muon magnetic moment. The frequency of the 1s-2s transition in the hydrogen-like atom can be determined with laser spectroscopy to obtain the muon mass. With such measurements fundamental physical interactions, in particular Quantum Electrodynamics, can also be tested at highest precision. The results are important input parameters for experiments on the muon magnetic anomaly. The simplicity of the atom enables further precise experiments, such as a search for muonium-antimuonium conversion for testing charged lepton number conservation and searches for possible antigravity of muons and dark matter.

  8. Probe into the clinical significance of target volume and change of the normal organs in image-guided radiotherapy for nasopharynegeal carcinoma

    International Nuclear Information System (INIS)

    Objective: To study the changes in gross tumor volume (GTV) and normal organs dur- ing intensity modulated radiation therapy (IMRT), and the probability of carrying out image-guided radio- therapy(IGRT) for nasopharyngeal carcinoma. Methods: Fifteen patients with nasopharyngeal carcinoma were treated by IMRT. CT was acquired before the planning, start of treatment and at the twenty-fifth time during radiotherapy. All images were fused with the second, third CT pictures and the initial CT pictures. Both GTV and normal tissues were manually contoured on every, axial slice to investigate the changes. Results: Primary tumor volume increased in two cases after finishing plan. Up to the twenty-fifth time during radiotherapy, primary tumors and parotid glands in volume decreased by 0-10.39 cm3 (gas volume) and 0.13-23.80 cm3; The shrunken degree correlated with the volume of the parotid glands before IMRT. The axial diameters of head decreased incoordinately. Conclusions: The primary tumor and normal tissue is changed during IMRT in nasopharyngeal carcinoma. The clinical consequences of these may be underdosage of tumor volume and/or overdosage of critical normal structures. Conclusively, the study is helpful in carrying out the second IMRT plan or IGRT for nasopharyngeal carcinoma. (authors)

  9. CRACUK user's guide

    International Nuclear Information System (INIS)

    The CRACUK computer code is a revised version of the US consequence modelling code CRAC2, adapted to suit UK applications. Modifications to various models within the code have led to certain changes in the input data requirements for CRACUK in comparison with CRAC2. This guide, written in the form of an Appendix to the CRAC2 User Guide, includes descriptions of the input data layout as it has been altered for use in CRACUK. Used in conjunction with the CRAC2 User Guide, this publication should allow easy use of the CRACUK code. (author)

  10. Precision temperature measurement system

    Directory of Open Access Journals (Sweden)

    Alina Pavel

    2009-10-01

    Full Text Available Nowadays there is a great variety of sensors for temperature measurements. The Pt100 is well known as one of the transducers with excellent precision and linearity. The only problem is the need of a high gain precision instrumentation amplifier which greatly increases the cost of the system. A large varriety of simple microcontrollers are developed to use with a lot of type of senzor which made the first translate of a nonelectric parameter in the electric form like pulse width or frequency or analogue voltage amplitude. After the signal was converted it can be transmited to an upper level to proces them.

  11. Precision electron polarimetry

    Energy Technology Data Exchange (ETDEWEB)

    Chudakov, Eugene A. [JLAB

    2013-11-01

    A new generation of precise Parity-Violating experiments will require a sub-percent accuracy of electron beam polarimetry. Compton polarimetry can provide such accuracy at high energies, but at a few hundred MeV the small analyzing power limits the sensitivity. M{\\o}ller polarimetry provides a high analyzing power independent on the beam energy, but is limited by the properties of the polarized targets commonly used. Options for precision polarimetry at ~300 MeV will be discussed, in particular a proposal to use ultra-cold atomic hydrogen traps to provide a 100\\%-polarized electron target for M{\\o}ller polarimetry.

  12. Precision genome editing

    DEFF Research Database (Denmark)

    Steentoft, Catharina; Bennett, Eric P; Schjoldager, Katrine Ter-Borch Gram;

    2014-01-01

    of glycobiology, primarily due to their low efficiencies, with resultant failure to impose substantial phenotypic consequences upon the final glycosylation products. Here, we review novel nuclease-based precision genome editing techniques enabling efficient and stable gene editing, including gene disruption...... by introducing single or double-stranded breaks at a defined genomic sequence. We here compare and contrast the different techniques and summarize their current applications, highlighting cases from the field of glycobiology as well as pointing to future opportunities. The emerging potential of precision gene...

  13. The innate responses of bumble bees to flower patterns: separating the nectar guide from the nectary changes bee movements and search time

    Science.gov (United States)

    Goodale, Eben; Kim, Edward; Nabors, Annika; Henrichon, Sara; Nieh, James C.

    2014-06-01

    Nectar guides can enhance pollinator efficiency and plant fitness by allowing pollinators to more rapidly find and remember the location of floral nectar. We tested if a radiating nectar guide around a nectary would enhance the ability of naïve bumble bee foragers to find nectar. Most experiments that test nectar guide efficacy, specifically radiating linear guides, have used guides positioned around the center of a radially symmetric flower, where nectaries are often found. However, the flower center may be intrinsically attractive. We therefore used an off-center guide and nectary and compared "conjunct" feeders with a nectar guide surrounding the nectary to "disjunct" feeders with a nectar guide separated from the nectary. We focused on the innate response of novice bee foragers that had never previously visited such feeders. We hypothesized that a disjunct nectar guide would conflict with the visual information provided by the nectary and negatively affect foraging. Approximately, equal numbers of bumble bees ( Bombus impatiens) found nectar on both feeder types. On disjunct feeders, however, unsuccessful foragers spent significantly more time (on average 1.6-fold longer) searching for nectar than any other forager group. Successful foragers on disjunct feeders approached these feeders from random directions unlike successful foragers on conjunct feeders, which preferentially approached the combined nectary and nectar guide. Thus, the nectary and a surrounding nectar guide can be considered a combination of two signals that attract naïve foragers even when not in the floral center.

  14. Precision Chemical Abundance Measurements

    DEFF Research Database (Denmark)

    Yong, David; Grundahl, Frank; Meléndez, Jorge;

    2012-01-01

    This talk covers preliminary work in which we apply a strictly differential line-by-line chemical abundance analysis to high quality UVES spectra of the globular cluster NGC 6752. We achieve extremely high precision in the measurement of relative abundance ratios. Our results indicate that the ob...

  15. Precision physics at LHC

    International Nuclear Information System (INIS)

    In this talk the author gives a brief survey of some physics topics that will be addressed by the Large Hadron Collider currently under construction at CERN. Instead of discussing the reach of this machine for new physics, the author gives examples of the types of precision measurements that might be made if new physics is discovered

  16. High Precision Measurements Using High Frequency Signals

    CERN Document Server

    Jin, Aohan; Sakurai, Atsunori; Liu, Liang; Edman, Fredrik; Öwall, Viktor; Pullerits, Tonu; Karki, Khadga J

    2014-01-01

    Generalized lock-in amplifiers use digital cavities with Q-factors as high as 5X10^8. In this letter, we show that generalized lock-in amplifiers can be used to analyze microwave (giga-hertz) signals with a precision of few tens of hertz. We propose that the physical changes in the medium of propagation can be measured precisely by the ultra-high precision measurement of the signal. We provide evidence to our proposition by verifying the Newton's law of cooling by measuring the effect of change in temperature on the phase and amplitude of the signals propagating through two calibrated cables. The technique could be used to precisely measure different physical properties of the propagation medium, for example length, resistance, etc. Real time implementation of the technique can open up new methodologies of in-situ virtual metrology in material design.

  17. The History of Land-Use Change in the South Florida Ecosystem: Paleoecologic Data as a Guide for Restoration

    Science.gov (United States)

    Wingard, G. L.; Cronin, T. M.; Dwyer, G. S.; Holmes, C. W.; Ishman, S. E.

    2003-12-01

    The south Florida ecosystem has undergone profound changes during the last century as a result of urbanization, agricultural development, and the construction of a massive water control system - the Central and Southern Florida (C&SF) Project. Created in 1948, the C&SF Project was designed for flood protection and to provide water for people and agricultural development. The extensive network of canals, levees, and water-control structures cover over 18,000 square miles and have completely altered the natural sheet flow of water across the land. Water was, and is, the principal driving force of this unique subtropical ecosystem, a significant portion of which is public land, including Everglades National Park, Biscayne National Park, Big Cypress National Preserve, the Florida Keys National Marine Sanctuary, Dry Tortugas National Park, and six National Wildlife Refuge Complexes. The Comprehensive Everglades Restoration Plan (CERP) has been designed in an effort to restore more natural water delivery to the ecosystem. This plan will cost over 8 billion dollars and take more than 30 years to complete. To successfully implement the CERP, land managers and restoration planners need answers to questions such as what are our restoration targets? What conditions are we restoring the system to? What portion of the changes seen in the 20th century can be attributed to land-use changes and what portion to natural change? What are the impacts on living resources? Paleoecologic and biochemical research is providing the answers to these questions. Analyses of cores from Florida Bay and Biscayne Bay have highlighted the following important findings. (1) Although land-use changes have played a role in determining salinity for Florida Bay as a whole, salinity is more strongly correlated to rainfall than any other single factor. (2) Anthropogenic activity influences the magnitude of salinity variations seen in recent times in Florida Bay, and they probably act on a local basis to

  18. The Future of Precision Medicine in Oncology.

    Science.gov (United States)

    Millner, Lori M; Strotman, Lindsay N

    2016-09-01

    Precision medicine in oncology focuses on identifying which therapies are most effective for each patient based on genetic characterization of the cancer. Traditional chemotherapy is cytotoxic and destroys all cells that are rapidly dividing. The foundation of precision medicine is targeted therapies and selecting patients who will benefit most from these therapies. One of the newest aspects of precision medicine is liquid biopsy. A liquid biopsy includes analysis of circulating tumor cells, cell-free nucleic acid, or exosomes obtained from a peripheral blood draw. These can be studied individually or in combination and collected serially, providing real-time information as a patient's cancer changes. PMID:27514468

  19. Precise nuclear physics for the sun

    International Nuclear Information System (INIS)

    For many centuries, the study of the Sun has been an important testbed for understanding stars that are further away. One of the first astronomical observations Galileo Galilei made in 1612 with the newly invented telescope concerned the sunspots, and in 1814, Joseph von Fraunhofer employed his new spectroscope to discover the absorption lines in the solar spectrum that are now named after him. Even though more refined and new modes of observation are now available than in the days of Galileo and Fraunhofer, the study of the Sun is still high on the agenda of contemporary science, due to three guiding interests. The first is connected to the ages-old human striving to understand the structure of the larger world surrounding us. Modern telescopes, some of them even based outside the Earth's atmosphere in space, have succeeded in observing astronomical objects that are billions of light-years away. However, for practical reasons precision data that are important for understanding stars can still only be gained from the Sun. In a sense, the observations of far-away astronomical objects thus call for a more precise study of the closeby, of the Sun, for their interpretation. The second interest stems from the human desire to understand the essence of the world, in particular the elementary particles of which it consists. Large accelerators have been constructed to produce and collide these particles. However, man-made machines can never be as luminous as the Sun when it comes to producing particles. Solar neutrinos have thus served not only as an astronomical tool to understand the Sun's inner workings, but their behavior on the way from the Sun to the Earth is also being studied with the aim to understand their nature and interactions. The third interest is strictly connected to life on Earth. A multitude of research has shown that even relatively slight changes in the Earth's climate may strongly affect the living conditions in a number of densely populated areas

  20. Precise nuclear physics for the sun

    Energy Technology Data Exchange (ETDEWEB)

    Bemmerer, Daniel

    2012-07-01

    For many centuries, the study of the Sun has been an important testbed for understanding stars that are further away. One of the first astronomical observations Galileo Galilei made in 1612 with the newly invented telescope concerned the sunspots, and in 1814, Joseph von Fraunhofer employed his new spectroscope to discover the absorption lines in the solar spectrum that are now named after him. Even though more refined and new modes of observation are now available than in the days of Galileo and Fraunhofer, the study of the Sun is still high on the agenda of contemporary science, due to three guiding interests. The first is connected to the ages-old human striving to understand the structure of the larger world surrounding us. Modern telescopes, some of them even based outside the Earth's atmosphere in space, have succeeded in observing astronomical objects that are billions of light-years away. However, for practical reasons precision data that are important for understanding stars can still only be gained from the Sun. In a sense, the observations of far-away astronomical objects thus call for a more precise study of the closeby, of the Sun, for their interpretation. The second interest stems from the human desire to understand the essence of the world, in particular the elementary particles of which it consists. Large accelerators have been constructed to produce and collide these particles. However, man-made machines can never be as luminous as the Sun when it comes to producing particles. Solar neutrinos have thus served not only as an astronomical tool to understand the Sun's inner workings, but their behavior on the way from the Sun to the Earth is also being studied with the aim to understand their nature and interactions. The third interest is strictly connected to life on Earth. A multitude of research has shown that even relatively slight changes in the Earth's climate may strongly affect the living conditions in a number of densely

  1. Precision Profits: The Economics of a Precision Agricultural Sprayer System

    OpenAIRE

    Batte, Marvin T.; Ehsani, Mohammad Reza

    2005-01-01

    Precision guidance and precision sprayer control have substantial promise to reduce input application overlap, thus saving chemicals, fuel, and time during the application process. In this report we provide preliminary estimates of the magnitude of the private benefits for a precision guidance system combined with auto-boom control for agricultural sprayers (precision spraying). Hypothetical farm fields are analyzed, allowing comparison of the performance of the precision system to a traditio...

  2. Precision Muon Physics

    CERN Document Server

    Gorringe, T P

    2015-01-01

    The muon is playing a unique role in sub-atomic physics. Studies of muon decay both determine the overall strength and establish the chiral structure of weak interactions, as well as setting extraordinary limits on charged-lepton-flavor-violating processes. Measurements of the muon's anomalous magnetic moment offer singular sensitivity to the completeness of the standard model and the predictions of many speculative theories. Spectroscopy of muonium and muonic atoms gives unmatched determinations of fundamental quantities including the magnetic moment ratio $\\mu_\\mu / \\mu_p$, lepton mass ratio $m_{\\mu} / m_e$, and proton charge radius $r_p$. Also, muon capture experiments are exploring elusive features of weak interactions involving nucleons and nuclei. We will review the experimental landscape of contemporary high-precision and high-sensitivity experiments with muons. One focus is the novel methods and ingenious techniques that achieve such precision and sensitivity in recent, present, and planned experiment...

  3. A passion for precision

    CERN Document Server

    CERN. Geneva

    2006-01-01

    For more than three decades, the quest for ever higher precision in laser spectroscopy of the simple hydrogen atom has inspired many advances in laser, optical, and spectroscopic techniques, culminating in femtosecond laser optical frequency combs  as perhaps the most precise measuring tools known to man. Applications range from optical atomic clocks and tests of QED and relativity to searches for time variations of fundamental constants. Recent experiments are extending frequency comb techniques into the extreme ultraviolet. Laser frequency combs can also control the electric field of ultrashort light pulses, creating powerful new tools for the emerging field of attosecond science.Organiser(s): L. Alvarez-Gaume / PH-THNote: * Tea & coffee will be served at 16:00.

  4. Precision disablement aiming system

    Energy Technology Data Exchange (ETDEWEB)

    Monda, Mark J.; Hobart, Clinton G.; Gladwell, Thomas Scott

    2016-02-16

    A disrupter to a target may be precisely aimed by positioning a radiation source to direct radiation towards the target, and a detector is positioned to detect radiation that passes through the target. An aiming device is positioned between the radiation source and the target, wherein a mechanical feature of the aiming device is superimposed on the target in a captured radiographic image. The location of the aiming device in the radiographic image is used to aim a disrupter towards the target.

  5. Quad precision delay generator

    International Nuclear Information System (INIS)

    A Quad Precision Delay Generator delays a digital edge by a programmed amount of time, varying from nanoseconds to microseconds. The output of this generator has an amplitude of the order of tens of volts and rise time of the order of nanoseconds. This was specifically designed and developed to meet the stringent requirements of the plasma focus experiments. Plasma focus is a laboratory device for producing and studying nuclear fusion reactions in hot deuterium plasma. 3 figs

  6. Local collectivities and climatic change. Are you ready? A guide for the adaptation devoted to the local collectivities; Collectivites locales et changement climatique. Etes-vous pret? Un guide pour l'adaptation a l'attention des collectivites locales

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    Facing the climatic change effects, it is necessary to develop a national but also regional adaptation policy to the global warming. This guide aims to give, to the local managers, information on the global warming and bring possible adaptation measures. The sectors of planning, buildings, transports, public health, environment and public information are discussed. (A.L.B.)

  7. Monitoring thicknesses along a line using SH guided waves

    Science.gov (United States)

    Howard, Richard; Cegla, Frederic

    2016-02-01

    Guided wave technology has been successfully implemented in the field of NDT as a defect screening technique for many years. The existing technique is able to detect large defects in pipes, albeit with limited sensitivity since the technique operates at low frequencies (10-70kHz). Ultrasonic wall thickness monitoring is also a well-established technique; using frequencies in the MHz range these spot measurements are able to measure precise wall thicknesses, but are very spatially selective. This project aims to explore the middle ground, using higher frequency guided waves to increase sensitivity whilst increasing the spatial area covered. SH guided waves (SH0 and SH1 modes) were sent between two transducers in a plate (simulating the propagation of a guided wave around the circumference of a pipe) and the time trace of the receiving transducer was analysed for changes in the group velocity as different defects were introduced into the plate. It is shown that the guided wave-defect interactions were too distorted for accurate thickness profiles to be extracted from line measurements. However, it is believed that this method can be a qualitative tool for defect screening.

  8. Guided labworks

    DEFF Research Database (Denmark)

    Jacobsen, Lærke Bang

    For the last 40 years physics education research has shown poor learning outcomes of guided labs. Still this is found to be a very used teaching method in the upper secodary schools. This study explains the teacher's choice of guided labs throught the concept of redesign as obstacle dislodgement...

  9. Identification of model newborn care practices through a positive deviance inquiry to guide behavior-change interventions in Haripur, Pakistan.

    Science.gov (United States)

    Marsh, David R; Sternin, Monique; Khadduri, Rolla; Ihsan, Tariq; Nazir, Raheel; Bari, Abdul; Lapping, Karin

    2002-12-01

    A positive deviance (PD) inquiry identifies uncommon, model practices that a follow-on program can spread. PD has been used to rehabilitate malnourished children, but not for improving newborn health. Save the Children Federation/US (SC) conducted newborn PD cycles in communities (total population about 5,000 each) in two project areas in Haripur District, Pakistan among Afghan refugees and among local Pakistanis. Each PD cycle included planning, community orientation, situation analysis, PD inquiries, and community feedback with action planning. PD inquiries were in-depth interviews to identify uncommon behaviors among surviving asphyxiated newborns, thriving low birthweight babies, surviving newborns who had danger signs, and normal newborns. The Afghan caregivers showed better use of services and some household practices than their Pakistani counterparts, consistent with duration of SC presence (15 years vs. 18 months, respectively). The practices of both groups for clean delivery, thermal control, immediate and exclusive breastfeeding, and fathers' involvement were weak. But PD individuals, families, and/or birth attendants modeled good maternal care and immediate, routine and special newborn care. Communities enthusiastically committed to change behavior and form neighborhood support groups for better newborn care, including a demand for hygienic delivery. The PD approach for the newborn is more complex than for child nutrition. Yet this pilot-test proposed a conceptual framework for household newborn care, suggested tools and methods for information gathering, identified PDs in two settings of different risk, galvanized SC staff to the potential of the approach, mobilized communities for better newborn health, and drafted a newborn PD training curricula. PMID:12503239

  10. Lasers the power and precision of light

    CERN Document Server

    Diels, Jean-Claude

    2011-01-01

    ""Lasers"" are active ingredients of our modern life, but they are inconspicuous as they often go unnoticed. This intuitive introductory guide will tell you all you want to know about laser technologies in very diverse fields from nuclear and particle physics to medicine, astronomy and ultra-precise metrology. The book is coherently focused on fundamentals, and is aimed to stimulate intuition about present and future applications, while unveiling the halo of myths around lasers. Written by reputable laser experts who think that science should be entertaining, this useful reference relies on si

  11. Soil processes as a guiding principle in precision agriculture

    OpenAIRE

    Alphen, van, E.J.

    2002-01-01

    The fact that conventional agricultural practices have many detrimental effects is widely acknowledged (Rabbinge, 1997). To mitigate these effects, Dutch policy makers have implemented environmental laws that are essentially based on characteristic indicators for groundwater quality. This has resulted in progressively tighter restrictions on the input of N fertilisers and a consistent reduction of the number of registered pesticides. Enforcement of these laws still creates considerable proble...

  12. Open Knowledge Representation Techniques and Its Application in Precision Forming Design

    Directory of Open Access Journals (Sweden)

    Wang Ping

    2016-01-01

    Full Text Available Precision forming knowledge of precision forging parts can be acquired from various sources and generally requires an effective representation for its efficient reuse. According to the specific characteristics of the precision forming of car forging parts, the precision forming engineering knowledge has been classified into several kinds with the method of the open knowledge representation techniques for the different kinds of knowledge proposed. The open representation techniques of precision forming knowledge and its application are described in detail, and combined with the development of the precision forming design system of the automotive starter guiding cylinder based on knowledge. The results show that the precision forming knowledge is represented in an effective way will solve the problem of fusion of precision forming knowledge and precision forming manufacturing, and improve greatly the utilization efficiency of the precision forming knowledge.

  13. Precision animal breeding

    OpenAIRE

    Flint, A.P.F.; WOOLLIAMS, J. A.

    2007-01-01

    We accept that we are responsible for the quality of life of animals in our care. We accept that the activities of man affect all the living things with which we share this planet. But we are slow to realize that as a result we have a duty of care for all living things. That duty extends to the breeding of animals for which we are responsible. When animals are bred by man for a purpose, the aim should be to meet certain goals: to improve the precision with which breeding outcomes can be predi...

  14. Ultra-precision bearings

    CERN Document Server

    Wardle, F

    2015-01-01

    Ultra-precision bearings can achieve extreme accuracy of rotation, making them ideal for use in numerous applications across a variety of fields, including hard disk drives, roundness measuring machines and optical scanners. Ultraprecision Bearings provides a detailed review of the different types of bearing and their properties, as well as an analysis of the factors that influence motion error, stiffness and damping. Following an introduction to basic principles of motion error, each chapter of the book is then devoted to the basic principles and properties of a specific type of bearin

  15. Electroweak precision tests

    International Nuclear Information System (INIS)

    This document aims at summarizing a dozen of years of the author's research in High Energy Physics, in particular dealing with precision tests of the electroweak theory. Parity violating asymmetries measurements at LEP with the ALEPH detector together with global consistency checks of the Kobayashi-Maskawa paradigm within the CKM-fitter group are gathered in the first part of the document. The second part deals with the unpublished instrumental work about the design, tests, productions and commissioning of the elements of the Pre-Shower detector of the LHCb spectrometer at LHC. Physics perspectives with LHCb are eventually discussed as a conclusion. (author)

  16. Precision mass measurements

    Science.gov (United States)

    Gläser, M.; Borys, M.

    2009-12-01

    Mass as a physical quantity and its measurement are described. After some historical remarks, a short summary of the concept of mass in classical and modern physics is given. Principles and methods of mass measurements, for example as energy measurement or as measurement of weight forces and forces caused by acceleration, are discussed. Precision mass measurement by comparing mass standards using balances is described in detail. Measurement of atomic masses related to 12C is briefly reviewed as well as experiments and recent discussions for a future new definition of the kilogram, the SI unit of mass.

  17. HBR guides

    CERN Document Server

    Duarte, Nancy; Dillon, Karen

    2015-01-01

    Master your most pressing professional challenges with this seven-volume set that collects the smartest best practices from leading experts all in one place. "HBR Guide to Better Business Writing" and "HBR Guide to Persuasive Presentations" help you perfect your communication skills; "HBR Guide to Managing Up and Across" and "HBR Guide to Office Politics" show you how to build the best professional relationships; "HBR Guide to Finance Basics for Managers" is the one book you'll ever need to teach you about the numbers; "HBR Guide to Project Management" addresses tough questions such as how to manage stakeholder expectations and how to manage uncertainty in a complex project; and "HBR Guide to Getting the Right Work Done" goes beyond basic productivity tips to teach you how to prioritize and focus on your work. This specially priced set of the most popular books in the series makes a perfect gift for aspiring leaders looking for trusted advice. Arm yourself with the advice you need to succeed on the job, from ...

  18. Precision and Accuracy Parameters in Structured Light 3-D Scanning

    DEFF Research Database (Denmark)

    Eiríksson, Eyþór Rúnar; Wilm, Jakob; Pedersen, David Bue;

    2016-01-01

    Structured light systems are popular in part because they can be constructed from off-the-shelf low cost components. In this paper we quantitatively show how common design parameters affect precision and accuracy in such systems, supplying a much needed guide for practitioners. Our quantitative m...

  19. Engineering analyses of large precision cathode strip chambers for GEM

    Energy Technology Data Exchange (ETDEWEB)

    Horvath, J.A.; Belser, F.C.; Pratuch, S.M.; Wuest, C.R. [Lawrence Livermore National Lab., CA (United States); Mitselmakher, G. [Superconducting Super Collider Lab., Dallas, TX (United States); Gordeev, A. [Institute of Theoretical and Experimental Physics, Moscow (Russian Federation); Johnson, C.V. [Lawrence Livermore National Lab., CA (United States)]|[Superconducting Super Collider Lab., Dallas, TX (United States); Polychronakos, V.A. [Brookhaven National Lab., Upton, NY (United States); Golutvin, I.A. [Joint Institute for Nuclear Research, Dubna (Russian Federation)

    1993-10-21

    Structural analyses of large precision cathode strip chambers performed up to the date of this publication are documented. Mechanical property data for typical chamber materials are included. This information, originally intended to be an appendix to the {open_quotes}CSC Structural Design Bible,{close_quotes} is presented as a guide for future designers of large chambers.

  20. SU-E-J-258: Inter- and Intra-Fraction Setup Stability and Couch Change Tolerance for Image Guided Radiation Therapy

    International Nuclear Information System (INIS)

    Purpose: Immobilization devices combine rigid patient fixation as well as comfort and play a key role providing the stability required for accurate radiation delivery. In the setup step, couch re-positioning needed to align the patient is derived via registration of acquired versus reference image. For subsequent fractions, replicating the initial setup should yield identical alignment errors when compared to the reference. This is not always the case and further couch re-positioning can be needed. An important quality assurance measure is to set couch tolerances beyond which additional investigations are needed. The purpose of this work was to study the inter-fraction couch changes needed to re-align the patient and the intra-fraction stability of the alignment as a guide to establish the couch tolerances. Methods: Data from twelve patients treated on the Accuray CyberKnife (CK) system for fractionated intracranial radiotherapy and immobilized with Aquaplast RT, U-frame, F-Head-Support (Qfix, PA, USA) was used. Each fraction involved image acquisitions and registration with the reference to re-align the patient. The absolute couch position corresponding to the approved setup alignment was recorded per fraction. Intra-fraction set-up corrections were recorded throughout the treatment. Results: The average approved setup alignment was 0.03±0.28mm, 0.15±0.22mm, 0.06±0.31mm in the L/R, A/P, S/I directions respectively and 0.00±0.35degrees, 0.03±0.32degrees, 0.08±0.45degrees for roll, pitch and yaw respectively. The inter-fraction reproducibility of the couch position was 6.65mm, 10.55mm, and 4.77mm in the L/R, A/P and S/I directions respectively and 0.82degrees, 0.71degrees for roll and pitch respectively. Intra-fraction monitoring showed small average errors of 0.21±0.21mm, 0.00±0.08mm, 0.23±0.22mm in the L/R, A/P, S/I directions respectively and 0.03±0.12degrees, 0.04±0.25degrees, and 0.13±0.15degrees in the roll, pitch and yaw respectively. Conclusion

  1. Precision muon physics

    Science.gov (United States)

    Gorringe, T. P.; Hertzog, D. W.

    2015-09-01

    The muon is playing a unique role in sub-atomic physics. Studies of muon decay both determine the overall strength and establish the chiral structure of weak interactions, as well as setting extraordinary limits on charged-lepton-flavor-violating processes. Measurements of the muon's anomalous magnetic moment offer singular sensitivity to the completeness of the standard model and the predictions of many speculative theories. Spectroscopy of muonium and muonic atoms gives unmatched determinations of fundamental quantities including the magnetic moment ratio μμ /μp, lepton mass ratio mμ /me, and proton charge radius rp. Also, muon capture experiments are exploring elusive features of weak interactions involving nucleons and nuclei. We will review the experimental landscape of contemporary high-precision and high-sensitivity experiments with muons. One focus is the novel methods and ingenious techniques that achieve such precision and sensitivity in recent, present, and planned experiments. Another focus is the uncommonly broad and topical range of questions in atomic, nuclear and particle physics that such experiments explore.

  2. Precision manufacturing using LIGA

    International Nuclear Information System (INIS)

    Our objective is the fabrication of small high-precision parts using LIGA, which can be used in a variety of industrial applications. LIGA is a combination of deep x-ray lithography, electroplating, and replication processes that enables the fabrication of microstructures with vertical dimensions several millimeters high, lateral dimensions in the micrometer range, and submicron tolerances. On beamline 10.3.2, at the Advanced Light Source (ALS), the Center for X-ray Optics (CXRO) has built an end station suitable for LIGA. The ALS is an excellent source of radiation for this application. The CXRO, in close collaboration with Sandia National Laboratory and the Jet Propulsion Laboratory, has developed the other essential process steps of mask making, resist development, x-ray exposure, and electroplating. This technology provides a powerful tool for mass production and miniaturization of mechanical systems into a dimensional regime not accessible by traditional manufacturing operations. We will present several applications that exploit the characteristics of the LIGA process: the fabrication of magnetic laminations for a high precision stepping motor; miniature octopole lens for advanced e-beam lithography; high-aspect-ratio x-ray collimating grids for astronomy; and microscopic tumblers for nuclear security. copyright 1996 American Institute of Physics

  3. Precision measurements in supersymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Feng, J.L.

    1995-05-01

    Supersymmetry is a promising framework in which to explore extensions of the standard model. If candidates for supersymmetric particles are found, precision measurements of their properties will then be of paramount importance. The prospects for such measurements and their implications are the subject of this thesis. If charginos are produced at the LEP II collider, they are likely to be one of the few available supersymmetric signals for many years. The author considers the possibility of determining fundamental supersymmetry parameters in such a scenario. The study is complicated by the dependence of observables on a large number of these parameters. He proposes a straightforward procedure for disentangling these dependences and demonstrate its effectiveness by presenting a number of case studies at representative points in parameter space. In addition to determining the properties of supersymmetric particles, precision measurements may also be used to establish that newly-discovered particles are, in fact, supersymmetric. Supersymmetry predicts quantitative relations among the couplings and masses of superparticles. The author discusses tests of such relations at a future e{sup +}e{sup {minus}} linear collider, using measurements that exploit the availability of polarizable beams. Stringent tests of supersymmetry from chargino production are demonstrated in two representative cases, and fermion and neutralino processes are also discussed.

  4. Precision Joining Center

    Energy Technology Data Exchange (ETDEWEB)

    Powell, J.W.; Westphal, D.A.

    1991-08-01

    A workshop to obtain input from industry on the establishment of the Precision Joining Center (PJC) was held on July 10--12, 1991. The PJC is a center for training Joining Technologists in advanced joining techniques and concepts in order to promote the competitiveness of US industry. The center will be established as part of the DOE Defense Programs Technology Commercialization Initiative, and operated by EG G Rocky Flats in cooperation with the American Welding Society and the Colorado School of Mines Center for Welding and Joining Research. The overall objectives of the workshop were to validate the need for a Joining Technologists to fill the gap between the welding operator and the welding engineer, and to assure that the PJC will train individuals to satisfy that need. The consensus of the workshop participants was that the Joining Technologist is a necessary position in industry, and is currently used, with some variation, by many companies. It was agreed that the PJC core curriculum, as presented, would produce a Joining Technologist of value to industries that use precision joining techniques. The advantage of the PJC would be to train the Joining Technologist much more quickly and more completely. The proposed emphasis of the PJC curriculum on equipment intensive and hands-on training was judged to be essential.

  5. Precision measurements in supersymmetry

    International Nuclear Information System (INIS)

    Supersymmetry is a promising framework in which to explore extensions of the standard model. If candidates for supersymmetric particles are found, precision measurements of their properties will then be of paramount importance. The prospects for such measurements and their implications are the subject of this thesis. If charginos are produced at the LEP II collider, they are likely to be one of the few available supersymmetric signals for many years. The author considers the possibility of determining fundamental supersymmetry parameters in such a scenario. The study is complicated by the dependence of observables on a large number of these parameters. He proposes a straightforward procedure for disentangling these dependences and demonstrate its effectiveness by presenting a number of case studies at representative points in parameter space. In addition to determining the properties of supersymmetric particles, precision measurements may also be used to establish that newly-discovered particles are, in fact, supersymmetric. Supersymmetry predicts quantitative relations among the couplings and masses of superparticles. The author discusses tests of such relations at a future e+e- linear collider, using measurements that exploit the availability of polarizable beams. Stringent tests of supersymmetry from chargino production are demonstrated in two representative cases, and fermion and neutralino processes are also discussed

  6. Medication Guide

    Science.gov (United States)

    ... Size Small Text Medium Text Large Text Contrast Dark on Light Light on Dark Donate Search Menu Donate What is Glaucoma? Care ... Low Vision Resources Medication Guide Resources on the Web » See All Articles Help the Cause Glaucoma affects ...

  7. Precise Point Positioning

    DEFF Research Database (Denmark)

    Zhang, Xiaohong

    determination’ based on the relationship between the point clouds on regular objects (e.g. flat top buildings) and the ground truth of the objects used for calibration. In order to extract the footprints on the objects, filtering was implemented before the calibration. Three example tests have been made and......This report presents the results of investigations to determine accurate positions of aircrafts in airborne surveys (airborne gravity and airborne lidar) using precise point positioning, and also introduces a new so called “stepwise geometric misalignment determination” method to retrieve the...... airborne lidar system misalignment angle by automating the matching of lidar data with ground truth. Kinematic GPS positioning has been widely used, but the available commercial software systems are normally only suitable for the short or medium range kinematic baseline. However, in polar areas, airborne...

  8. Precision Tau Physics

    CERN Document Server

    Pich, Antonio

    2013-01-01

    Precise measurements of the lepton properties provide stringent tests of the Standard Model and accurate determinations of its parameters. We overview the present status of tau physics, highlighting the most recent developments, and discuss the prospects for future improvements. The leptonic decays of the tau lepton probe the structure of the weak currents and the universality of their couplings to the W boson. The universality of the leptonic Z couplings has also been tested through leptonic Z decays. The hadronic tau decay modes constitute an ideal tool for studying low-energy effects of the strong interaction in very clean conditions. Accurate determinations of the QCD coupling and the Cabibbo mixing have been obtained with tau data. The large mass of the tau opens the possibility to study many kinematically-allowed exclusive decay modes and extract relevant dynamical information. Violations of flavour and CP conservation laws can also be searched for with tau decays. Related subjects such as muon decays, ...

  9. Experimental Precision and Variety Comparison Precision in Regional Crop Trials

    Institute of Scientific and Technical Information of China (English)

    KONG Fan-ling; ZHANG Qun-yuan; GE Zhi-nan; YANG Fu-xin; ZHANG De-gui; LIU Wen-xin

    2002-01-01

    According to the basic concepts of precision and the principles of analysis of variance (ANOVA), precision types for experiments and variety comparison in regional crop trials (RCT) were studied and developed; expected variety comparison precision (EVCP) and realized variety comparison precision (RVCP) and the corresponding statistical indexes of them were proposed. It was explained that experimental precision (EP) and variety comparison precision (VCP) are two kinds of precision of RCT; EP includes error precision and variety mean precision, which can be measured respectively by the coefficient of variation of single observation's error (CVe) and the coefficient of variation of variety mean's error (CVY); VCP includes EVCP and RVCP, which can be measured respectively by the detectable least relative difference (DLRD) and the relative least significant distance (RLSD); EP is an important factor of VCP but not identical to it; RVCP is the realization of EVCP. Besides error, experimental design and GE interaction and ANOVA model affect VCP. Several application examples for these precision indexes were presented, and the precision of regional cotton trials in the Yellow River Valley and the Changjiang Valley were investigated through the historical data of RCTs from 1980 to 1999.

  10. Simple guide to Skype

    CERN Document Server

    Winter, Rick

    2013-01-01

    Simple Guides give you Just the Facts Get up to speed with Skypefast! Simple Guides: get you started quickly. No extra clutter, no extra reading. Learn how to set up Skype, as well as how to add and set up all your friends, family, and other contacts. Find out about all the features of Skype, how to change views, set your status and conduct video and audio only calls. Learn about all the different things you can do to contact your friends and family on Skype for free, and start having fun!

  11. Pneumatic conveying design guide

    CERN Document Server

    Mills, David

    1990-01-01

    Pneumatic Conveying Design Guide is a guide for the design of pneumatic conveying systems and includes detailed data and information on the conveying characteristics of a number of materials with a wide range of properties. This book includes logic diagrams for design procedures and scaling parameters for the conveying line configuration. It also explains how to improve the performance of pneumatic conveyors by optimizing, uprating, and extending the system or adapting it for a change of material. This book consists of 15 chapters divided into three sections and opens with an overview of the s

  12. Windows Vista Administrator's Pocket Guide

    CERN Document Server

    Stanek, William R

    2007-01-01

    Portable and precise, this pocket-sized guide delivers immediate answers for the day-to-day administration of Windows Vista. Zero in on core support and maintenance tasks using quick-reference tables, instructions, and lists. You'll get the precise information you need to solve problems and get the job done-whether you're at your desk or in the field! Get fast facts to: Install and configure Windows Vista-and optimize the user workspaceMaintain operating system components, hardware devices, and driversCreate user and group accounts-and control rights and permissionsAdminister group policy se

  13. Single mode, extreme precision Doppler spectrographs

    CERN Document Server

    Schwab, Christian; Betters, Christopher H; Bland-Hawthorn, Joss; Mahadevan, Suvrath

    2012-01-01

    The 'holy grail' of exoplanet research today is the detection of an earth-like planet: a rocky planet in the habitable zone around a main-sequence star. Extremely precise Doppler spectroscopy is an indispensable tool to find and characterize earth-like planets; however, to find these planets around solar-type stars, we need nearly one order of magnitude better radial velocity (RV) precision than the best current spectrographs provide. Recent developments in astrophotonics (Bland-Hawthorn & Horton 2006, Bland-Hawthorn et al. 2010) and adaptive optics (AO) enable single mode fiber (SMF) fed, high resolution spectrographs, which can realize the next step in precision. SMF feeds have intrinsic advantages over multimode fiber or slit coupled spectrographs: The intensity distribution at the fiber exit is extremely stable, and as a result the line spread function of a well-designed spectrograph is fully decoupled from input coupling conditions, like guiding or seeing variations (Ihle et al. 2010). Modal noise, a...

  14. Engineering, Trade, and Technical Cluster. Task Analyses. Drafting and Design Technology, Precision Machining Technology, Electronics Technology.

    Science.gov (United States)

    Henrico County Public Schools, Glen Allen, VA. Virginia Vocational Curriculum and Resource Center.

    Developed in Virginia, this publication contains task analysis guides to support selected tech prep programs that prepare students for careers in the engineering, trade, and technical cluster. Three occupations are profiled: drafting and design technology, precision machining technology, and electronics technology. Each guide contains the…

  15. Ultrasonic precision optical grinding technology

    Science.gov (United States)

    Cahill, Michael J.; Bechtold, Michael J.; Fess, Edward; Wolfs, Frank L.; Bechtold, Rob

    2015-10-01

    As optical geometries become more precise and complex and a wider range of materials are used, the processes used for manufacturing become more critical. As the preparatory stage for polishing, this is especially true for grinding. Slow processing speeds, accelerated tool wear, and poor surface quality are often detriments in manufacturing glass and hard ceramics. The quality of the ground surface greatly influences the polishing process and the resulting finished product. Through extensive research and development, OptiPro Systems has introduced an ultrasonic assisted grinding technology, OptiSonic, which has numerous advantages over traditional grinding processes. OptiSonic utilizes a custom tool holder designed to produce oscillations in line with the rotating spindle. A newly developed software package called IntelliSonic is integral to this platform. IntelliSonic automatically characterizes the tool and continuously optimizes the output frequency for optimal cutting while in contact with the part. This helps maintain a highly consistent process under changing load conditions for a more accurate surface. Utilizing a wide variety of instruments, test have proven to show a reduction in tool wear and increase in surface quality while allowing processing speeds to be increased. OptiSonic has proven to be an enabling technology to overcome the difficulties seen in grinding of glass and hard optical ceramics. OptiSonic has demonstrated numerous advantages over the standard CNC grinding process. Advantages are evident in reduced tool wear, better surface quality, and reduced cycle times due to increased feed rates. These benefits can be seen over numerous applications within the precision optics industry.

  16. Precise Truss Assembly Using Commodity Parts and Low Precision Welding

    Science.gov (United States)

    Komendera, Erik; Reishus, Dustin; Dorsey, John T.; Doggett, W. R.; Correll, Nikolaus

    2014-01-01

    Hardware and software design and system integration for an intelligent precision jigging robot (IPJR), which allows high precision assembly using commodity parts and low-precision bonding, is described. Preliminary 2D experiments that are motivated by the problem of assembling space telescope optical benches and very large manipulators on orbit using inexpensive, stock hardware and low-precision welding are also described. An IPJR is a robot that acts as the precise "jigging", holding parts of a local structure assembly site in place, while an external low precision assembly agent cuts and welds members. The prototype presented in this paper allows an assembly agent (for this prototype, a human using only low precision tools), to assemble a 2D truss made of wooden dowels to a precision on the order of millimeters over a span on the order of meters. The analysis of the assembly error and the results of building a square structure and a ring structure are discussed. Options for future work, to extend the IPJR paradigm to building in 3D structures at micron precision are also summarized.

  17. Single Mode, Extreme Precision Doppler Spectrographs

    Science.gov (United States)

    Schwab, Christian; Leon-Saval, Sergio G.; Betters, Christopher H.; Bland-Hawthorn, Joss; Mahadevan, Suvrath

    2014-04-01

    The `holy grail' of exoplanet research today is the detection of an earth-like planet: a rocky planet in the habitable zone around a main-sequence star. Extremely precise Doppler spectroscopy is an indispensable tool to find and characterize earth-like planets; however, to find these planets around solar-type stars, we need nearly one order of magnitude better radial velocity (RV) precision than the best current spectrographs provide. Recent developments in astrophotonics (Bland-Hawthorn & Horton 2006, Bland-Hawthorn et al. 2010) and adaptive optics (AO) enable single mode fiber (SMF) fed, high resolution spectrographs, which can realize the next step in precision. SMF feeds have intrinsic advantages over multimode fiber or slit coupled spectrographs: The intensity distribution at the fiber exit is extremely stable, and as a result the line spread function of a well-designed spectrograph is fully decoupled from input coupling conditions, like guiding or seeing variations (Ihle et al. 2010). Modal noise, a limiting factor in current multimode fiber fed instruments (Baudrand & Walker 2001), can be eliminated by proper design, and the diffraction limited input to the spectrograph allows for very compact instrument designs, which provide excellent optomechanical stability. A SMF is the ideal interface for new, very precise wavelength calibrators, like laser frequency combs (Steinmetz et al. 2008, Osterman et al. 2012), or SMF based Fabry-Perot Etalons (Halverson et al. 2013). At near infrared wavelengths, these technologies are ready to be implemented in on-sky instruments, or already in use. We discuss a novel concept for such a spectrograph.

  18. Precisely parameterized experimental and computational models of tissue organization.

    Science.gov (United States)

    Molitoris, Jared M; Paliwal, Saurabh; Sekar, Rajesh B; Blake, Robert; Park, JinSeok; Trayanova, Natalia A; Tung, Leslie; Levchenko, Andre

    2016-02-01

    Patterns of cellular organization in diverse tissues frequently display a complex geometry and topology tightly related to the tissue function. Progressive disorganization of tissue morphology can lead to pathologic remodeling, necessitating the development of experimental and theoretical methods of analysis of the tolerance of normal tissue function to structural alterations. A systematic way to investigate the relationship of diverse cell organization to tissue function is to engineer two-dimensional cell monolayers replicating key aspects of the in vivo tissue architecture. However, it is still not clear how this can be accomplished on a tissue level scale in a parameterized fashion, allowing for a mathematically precise definition of the model tissue organization and properties down to a cellular scale with a parameter dependent gradual change in model tissue organization. Here, we describe and use a method of designing precisely parameterized, geometrically complex patterns that are then used to control cell alignment and communication of model tissues. We demonstrate direct application of this method to guiding the growth of cardiac cell cultures and developing mathematical models of cell function that correspond to the underlying experimental patterns. Several anisotropic patterned cultures spanning a broad range of multicellular organization, mimicking the cardiac tissue organization of different regions of the heart, were found to be similar to each other and to isotropic cell monolayers in terms of local cell-cell interactions, reflected in similar confluency, morphology and connexin-43 expression. However, in agreement with the model predictions, different anisotropic patterns of cell organization, paralleling in vivo alterations of cardiac tissue morphology, resulted in variable and novel functional responses with important implications for the initiation and maintenance of cardiac arrhythmias. We conclude that variations of tissue geometry and topology

  19. Individual Assessment of Brain Tissue Changes in MS and the Effect of Focal Lesions on Short-Term Focal Atrophy Development in MS: A Voxel-Guided Morphometry Study

    OpenAIRE

    Jan Fox; Matthias Kraemer; Thorsten Schormann; Andreas Dabringhaus; Jochen Hirsch; Philipp Eisele; Kristina Szabo; Christel Weiss; Michael Amann; Katrin Weier; Yvonne Naegelin; Ludwig Kappos; Achim Gass

    2016-01-01

    We performed voxel-guided morphometry (VGM) investigating the mechanisms of brain atrophy in multiple sclerosis (MS) related to focal lesions. VGM maps detect regional brain changes when comparing 2 time points on high resolution T1-weighted (T1w) magnetic resonace imaging (MRI). Two T1w MR datasets from 92 relapsing-remitting MS patients obtained 12 months apart were analysed with VGM. New lesions and volume changes of focal MS lesions as well as in the surrounding tissue were identified by ...

  20. Dramatic change in a young woman’s perception of her diabetes and remarkable reduction in HbA1c after an individual course of Guided Self-Determination

    DEFF Research Database (Denmark)

    Prip, Anne; Christiansen, Anette Wendelboe; Zoffmann, Vibeke

    2015-01-01

    A 24-year-old woman with type 1 diabetes participated in a randomised controlled trial proving effectiveness of a flexible Guided Self-Determination (GSD) intervention. She had for 10 years been living with a complex situation of eating disorder, poor glycaemic control, non-attendance and...... psychosocial distress. She managed to change her perception of diabetes dramatically and improved her glycaemic control. Considering the complexity of her case, we explored how she achieved these changes. A GSD-trained nurse delivered the intervention, which involves reflection sheets and advanced professional...

  1. Precision Adjustable Liquid Regulator (ALR)

    Science.gov (United States)

    Meinhold, R.; Parker, M.

    2004-10-01

    A passive mechanical regulator has been developed for the control of fuel or oxidizer flow to a 450N class bipropellant engine for use on commercial and interplanetary spacecraft. There are several potential benefits to the propulsion system, depending on mission requirements and spacecraft design. This system design enables more precise control of main engine mixture ratio and inlet pressure, and simplifies the pressurization system by transferring the function of main engine flow rate control from the pressurization/propellant tank assemblies, to a single component, the ALR. This design can also reduce the thermal control requirements on the propellant tanks, avoid costly Qualification testing of biprop engines for missions with more stringent requirements, and reduce the overall propulsion system mass and power usage. In order to realize these benefits, the ALR must meet stringent design requirements. The main advantage of this regulator over other units available in the market is that it can regulate about its nominal set point to within +/-0.85%, and change its regulation set point in flight +/-4% about that nominal point. The set point change is handled actively via a stepper motor driven actuator, which converts rotary into linear motion to affect the spring preload acting on the regulator. Once adjusted to a particular set point, the actuator remains in its final position unpowered, and the regulator passively maintains outlet pressure. The very precise outlet regulation pressure is possible due to new technology developed by Moog, Inc. which reduces typical regulator mechanical hysteresis to near zero. The ALR requirements specified an outlet pressure set point range from 225 to 255 psi, and equivalent water flow rates required were in the 0.17 lb/sec range. The regulation output pressure is maintained at +/-2 psi about the set point from a P (delta or differential pressure) of 20 to over 100 psid. Maximum upstream system pressure was specified at 320 psi

  2. Micro-precise spatiotemporal delivery system embedded in 3D printing for complex tissue regeneration.

    Science.gov (United States)

    Tarafder, Solaiman; Koch, Alia; Jun, Yena; Chou, Conrad; Awadallah, Mary R; Lee, Chang H

    2016-06-01

    Three dimensional (3D) printing has emerged as an efficient tool for tissue engineering and regenerative medicine, given its advantages for constructing custom-designed scaffolds with tunable microstructure/physical properties. Here we developed a micro-precise spatiotemporal delivery system embedded in 3D printed scaffolds. PLGA microspheres (μS) were encapsulated with growth factors (GFs) and then embedded inside PCL microfibers that constitute custom-designed 3D scaffolds. Given the substantial difference in the melting points between PLGA and PCL and their low heat conductivity, μS were able to maintain its original structure while protecting GF's bioactivities. Micro-precise spatial control of multiple GFs was achieved by interchanging dispensing cartridges during a single printing process. Spatially controlled delivery of GFs, with a prolonged release, guided formation of multi-tissue interfaces from bone marrow derived mesenchymal stem/progenitor cells (MSCs). To investigate efficacy of the micro-precise delivery system embedded in 3D printed scaffold, temporomandibular joint (TMJ) disc scaffolds were fabricated with micro-precise spatiotemporal delivery of CTGF and TGFβ3, mimicking native-like multiphase fibrocartilage. In vitro, TMJ disc scaffolds spatially embedded with CTGF/TGFβ3-μS resulted in formation of multiphase fibrocartilaginous tissues from MSCs. In vivo, TMJ disc perforation was performed in rabbits, followed by implantation of CTGF/TGFβ3-μS-embedded scaffolds. After 4 wks, CTGF/TGFβ3-μS embedded scaffolds significantly improved healing of the perforated TMJ disc as compared to the degenerated TMJ disc in the control group with scaffold embedded with empty μS. In addition, CTGF/TGFβ3-μS embedded scaffolds significantly prevented arthritic changes on TMJ condyles. In conclusion, our micro-precise spatiotemporal delivery system embedded in 3D printing may serve as an efficient tool to regenerate complex and inhomogeneous tissues. PMID

  3. Dramatic enhancement of genome editing by CRISPR/Cas9 through improved guide RNA design.

    Science.gov (United States)

    Farboud, Behnom; Meyer, Barbara J

    2015-04-01

    Success with genome editing by the RNA-programmed nuclease Cas9 has been limited by the inability to predict effective guide RNAs and DNA target sites. Not all guide RNAs have been successful, and even those that were, varied widely in their efficacy. Here we describe and validate a strategy for Caenorhabditis elegans that reliably achieved a high frequency of genome editing for all targets tested in vivo. The key innovation was to design guide RNAs with a GG motif at the 3' end of their target-specific sequences. All guides designed using this simple principle induced a high frequency of targeted mutagenesis via nonhomologous end joining (NHEJ) and a high frequency of precise DNA integration from exogenous DNA templates via homology-directed repair (HDR). Related guide RNAs having the GG motif shifted by only three nucleotides showed severely reduced or no genome editing. We also combined the 3' GG guide improvement with a co-CRISPR/co-conversion approach. For this co-conversion scheme, animals were only screened for genome editing at designated targets if they exhibited a dominant phenotype caused by Cas9-dependent editing of an unrelated target. Combining the two strategies further enhanced the ease of mutant recovery, thereby providing a powerful means to obtain desired genetic changes in an otherwise unaltered genome. PMID:25695951

  4. Centroid precision and orientation precision of planar localization microscopy.

    Science.gov (United States)

    McGray, C; Copeland, C R; Stavis, S M; Geist, J

    2016-09-01

    The concept of localization precision, which is essential to localization microscopy, is formally extended from optical point sources to microscopic rigid bodies. Measurement functions are presented to calculate the planar pose and motion of microscopic rigid bodies from localization microscopy data. Physical lower bounds on the associated uncertainties - termed centroid precision and orientation precision - are derived analytically in terms of the characteristics of the optical measurement system and validated numerically by Monte Carlo simulations. The practical utility of these expressions is demonstrated experimentally by an analysis of the motion of a microelectromechanical goniometer indicated by a sparse constellation of fluorescent nanoparticles. Centroid precision and orientation precision, as developed here, are useful concepts due to the generality of the expressions and the widespread interest in localization microscopy for super-resolution imaging and particle tracking. PMID:26970565

  5. Atomic physics precise measurements and ultracold matter

    CERN Document Server

    Inguscio, Massimo

    2013-01-01

    Atomic Physics provides an expert guide to two spectacular new landscapes in physics: precision measurements, which have been revolutionized by the advent of the optical frequency comb, and atomic physics, which has been revolutionized by laser cooling. These advances are not incremental but transformative: they have generated a consilience between atomic and many-body physics, precipitated an explosion of scientific and technological applications, opened new areas of research, and attracted a brilliant generation of younger scientists. The research is advancing so rapidly, the barrage of applications is so dazzling, that students can be bewildered. For both students and experienced scientists, this book provides an invaluable description of basic principles, experimental methods, and scientific applications.

  6. Geometrical precision of 3DP casting form for founding gears

    Directory of Open Access Journals (Sweden)

    T. Markowski

    2010-01-01

    Full Text Available The article presents analysis of geometrical precision of casting form made by means of 3DP method. Three dimentional printing is a universal method of rapid prototyping which can be used to make tools – castings forms as a Rapid Tooling method. By means of this method in direct incremental process a casting form of spur gear was created. Precision of creating the form by 3DP method depends on different factors. Technological factors depending on machine operator include: the thickness of the layer and placing the model in working space. The precision of creating the model also depends on preparing the printer for work: the condition and calibration of printing heads, the condition of the printing unit slide guides and preparing the working space. Three dimentional printer Z510 Spectrum was prepared for work in a way assuring the greatest precision of created models. Technological parameters responsible for precision were set on maximum values. The aim of the research was defining the precision of casting form generated by 3DP Rapid Prototyping Method. The research was made by means of coordinate measuring machine Wenzel LH87. The measuring machine software was used to compare the outcome of the measurement to nominal model 3D-CAD. The problem of tool precision of casting forms generated by Rapid Tooling is rarely considered in literature covering rapid prototyping and casting technologies. That is why the research presented in this article isan original work in the technological and practical aspect.

  7. Precision Farming. A Comprehensive Approach

    OpenAIRE

    Grisso, Robert D. (Robert Dwight), 1956-; Alley, Mark M.; McClellan, Phil; Brann, Daniel Edward, 1945-; Donohue, Stephen J.

    2005-01-01

    Precision Farming (PF), also referred to as precision agriculture or variable rate technology, is the process used to vary management of crop production across a field. This publication introduces the principles and terminology used in PF. Crop producers can use this information to gain a working knowledge of PF and develop the ability to implement PF technologies in traditional crop production.

  8. PRECISION FARMING FOR NITROGEN MANAGEMENT

    Science.gov (United States)

    Approaches to precision nitrogen management vary from region to region depending on crop, soils, landscape, and climate yet all strategies essentially attempt to estimate crop nitrogen demand or plant available nitrogen. In this chapter, we provide case studies that illustrate precision nitrogen ma...

  9. How evolution guides complexity

    OpenAIRE

    LARRY S. YAEGER

    2009-01-01

    Long-standing debates about the role of natural selection in the growth of biological complexity over geological time scales are difficult to resolve from the paleobiological record. Using an evolutionary model—a computational ecosystem subjected to natural selection—we investigate evolutionary trends in an information-theoretic measure of the complexity of the neural dynamics of artificial agents inhabiting the model. Our results suggest that evolution always guides complexity change, just n...

  10. Precision Agriculture Technologies Using in Irrigation

    OpenAIRE

    EMEKLİ, Nefise Yasemin; TOPAKCI, Mehmet

    2009-01-01

    : One of the most important subjects in crop production is to optimise yield while minimizing inputs. Precision Agriculture could obtain efficient use of inputs such as seed, fertilizer, pesticide etc. as respect to environment by considering the spatial and temporal changes in field according to crop and soil properties. This new method is an approach which can provide with the new technologies using in agriculture. Remote sensing, Geographic Information Systems, and Global Positioning Syste...

  11. A computational intelligence approach to the Mars Precision Landing problem

    Science.gov (United States)

    Birge, Brian Kent, III

    Various proposed Mars missions, such as the Mars Sample Return Mission (MRSR) and the Mars Smart Lander (MSL), require precise re-entry terminal position and velocity states. This is to achieve mission objectives including rendezvous with a previous landed mission, or reaching a particular geographic landmark. The current state of the art footprint is in the magnitude of kilometers. For this research a Mars Precision Landing is achieved with a landed footprint of no more than 100 meters, for a set of initial entry conditions representing worst guess dispersions. Obstacles to reducing the landed footprint include trajectory dispersions due to initial atmospheric entry conditions (entry angle, parachute deployment height, etc.), environment (wind, atmospheric density, etc.), parachute deployment dynamics, unavoidable injection error (propagated error from launch on), etc. Weather and atmospheric models have been developed. Three descent scenarios have been examined. First, terminal re-entry is achieved via a ballistic parachute with concurrent thrusting events while on the parachute, followed by a gravity turn. Second, terminal re-entry is achieved via a ballistic parachute followed by gravity turn to hover and then thrust vector to desired location. Third, a guided parafoil approach followed by vectored thrusting to reach terminal velocity is examined. The guided parafoil is determined to be the best architecture. The purpose of this study is to examine the feasibility of using a computational intelligence strategy to facilitate precision planetary re-entry, specifically to take an approach that is somewhat more intuitive and less rigid, and see where it leads. The test problems used for all research are variations on proposed Mars landing mission scenarios developed by NASA. A relatively recent method of evolutionary computation is Particle Swarm Optimization (PSO), which can be considered to be in the same general class as Genetic Algorithms. An improvement over

  12. [MRI-guided musculoskeletal biopsy].

    Science.gov (United States)

    Daecke, W; Libicher, M; Mädler, U; Rumpf, C; Bernd, L

    2003-02-01

    MRI-guided musculoskeletal biopsy has been mentioned to be a minimally invasive method to obtain specimens for diagnostic purposes in bone tumors. To evaluate the viability, to assess the accuracy, and to record possible complications of this method, clinical data of 19 MRI-guided biopsies were analyzed. Interventions were performed on 18 patients (1-78 years) as an outpatient procedure: 15 skeletal and 4 soft tissue biopsies were taken from the pelvis, upper limb,or lower limb. We used T1-weighted gradient echoes (GE) for locating the puncture site and T2-weighted turbo spin echoes (TSE) for visualization of needle position. In 14 of 18 MRI-guided biopsies, a definite histological diagnosis was obtained. According to the pathologist, the inadequate size of the specimen was the main reason for missing the diagnoses in four cases.Long intervention time and inappropriate biopsy tools proved to be the main disadvantages of MRI-guided biopsy, but technical improvement might solve these technical problems in future.A postbiopsy hematoma was the only complication observed. Once technically improved, MRI-guided biopsy could be a precise alternative routine method for musculoskeletal biopsies in future. PMID:12607083

  13. Guided Reading: The Romance and the Reality

    Science.gov (United States)

    Fountas, Irene C.; Pinnell, Gay Su

    2013-01-01

    The authors examine the growth and impact of guided reading, small group teaching for differentiated instruction in reading that was stimulated by their early publications. Many changes in literacy education have been observed as a result--almost as if educators had a "romance" with guided reading and leveled books. While changes have been…

  14. GUIDE FOR POLARIZED NEUTRONS

    Science.gov (United States)

    Sailor, V.L.; Aichroth, R.W.

    1962-12-01

    The plane of polarization of a beam of polarized neutrons is changed by this invention, and the plane can be flipped back and forth quicitly in two directions in a trouble-free manner. The invention comprises a guide having a plurality of oppositely directed magnets forming a gap for the neutron beam and the gaps are spaced longitudinally in a spiral along the beam at small stepped angles. When it is desired to flip the plane of polarization the magnets are suitably rotated to change the direction of the spiral of the gaps. (AEC)

  15. SYNTHESIS OF GUIDED CHAIN DRIVE MECHANISM WITH LINKAGE

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    A method of designing guided chain drive mechanism with linkage basing on the given motion track is expounded. The method consists of two steps that are synthesizing four-bar linkage approximately first and then deducing guide track, removing crank and jointing free end with chain. An example of synthesis that can realize the given motion track precisely is provided.

  16. SQL Pocket Guide

    CERN Document Server

    Gennick, Jonathan

    2010-01-01

    If you're a programmer or database administrator who uses SQL in your day-to-day work, this popular pocket guide is the ideal on-the-job reference. You'll find many examples that address the language's complexity, along with key aspects of SQL used in IBM DB2 Release 9.7, MySQL 5.1, Oracle Database 11g Release 2, PostgreSQL 9.0, and Microsoft SQL Server 2008 Release 2. SQL Pocket Guide describes how these database systems implement SQL syntax for querying, managing transactions, and making changes to data. It also shows how the systems use SQL functions, regular expression syntax, and type c

  17. US-guided preoperative hook-wire localization of nonpalpable breast lesions

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Tae Beom; Lee, Sang Kwon; Kim, Hye Jung; Ryeom, Hun Kyu; Kim, Tae Hun; Kim, Yong Ju; Kang, Duk Sik; Lee, Young Ha; Park, Ho Yong [Kyungpook National University College of Medicine, Taegu (Korea, Republic of)

    2000-12-15

    To evaluate the feasibility and efficacy of US-guided preoperative wire localization of nonpalpable breast lesions. US-guided preoperative wire localization was performed upon 45 nonpalpable breast lesions including 14 nonpalpable masses, 11 nonpalpable masses with microcalcifications, 11 ductal lesions, 9 with microcalcifications. No local anesthesia was performed during the localization procedure. Under the US-guidance, the needle with the hook-wire was inserted into the lesion until the hook of the wire reached 1 cm beyond the posterior margin of the lesion. Precise wire positioning was confirmed by mammography. Specimen radiography or specimen ultrasonography was performed in all cases. US-guided preoperative wire localization was successfully achieved in all cases. The time required for US-guided wire localization was less than five minutes. All lesions were successfully removed by surgical excision. Successful removal was confirmed by specimen radiography or specimen ultrasonography, gross findings of the specimen and consistency between radiographic and pathologic findings. The histologic diagnosis of 45 lesions were 7 ductal carcinoma in situ, 8 invasive ductal carcinoma, 6 fibroadenoma, 8 intraductal papilloma, 2 atypical ductal hyperplasia, and 14 fibrocystic changes. No complications were occurred during and after the procedure. US-guided preoperative wire localization for excisional biopsy is simple, safe, and accurate method in the histologic diagnosis of nonpalpable breast lesions detectable with ultrasonography.

  18. High-precision multipass reflectometer

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, D.F.; Baumeister, P.

    1981-01-01

    The multipass reflectometer has been shown to be a convenient and precise instrument for the measurement of spectral reflectances in excess of 0.99. This report gives a brief sketch of the initial setup of the reflectometer, its operation, optimization of parameters, and some limitations to the expected precision. The instrumental precision is set by the uncertainty in the computer fit of a straight line to the measured data. Systematic errors due to nonuniform photosurfaces and the effects of astigmatism have been minimized. We have used this reflectrometer to measure the absolute reflectance of evaporated aluminum films in the uv and visible regions. It has also been used to measure the low-level insertion losses of laser window materials for this same spectral region.

  19. The magic road to precision

    CERN Document Server

    Safronova, M S; Safronova, U I; Clark, Charles W

    2015-01-01

    We predict a sequence of magic-zero wavelengths for the Sr excited $5s5p~ ^3P_0$ state, and provide a general roadmap for extracting transition matrix elements using precise frequency measurements. We demonstrate that such measurements can serve as a best global benchmark of the spectroscopic accuracy that is required for the development of high-precision predictive methods. These magic-zero wavelengths are also needed for state-selective atom manipulation for implementation of quantum logic operations. We also identify five magic wavelengths of the $5s^2\\ ^1S_0 - 5s5p\\ ^3P_0$ Sr clock transition between 350 nm and 500 nm which can also serve as precision benchmarks.

  20. Investigation on the use of artificial neural networks to overcome the effects of environmental and operational changes on guided waves monitoring

    Science.gov (United States)

    El Mountassir, M.; Yaacoubi, S.; Dahmene, F.

    2015-07-01

    Intelligent feature extraction and advanced signal processing techniques are necessary for a better interpretation of ultrasonic guided waves signals either in structural health monitoring (SHM) or in nondestructive testing (NDT). Such signals are characterized by at least multi-modal and dispersive components. In addition, in SHM, these signals are closely vulnerable to environmental and operational conditions (EOCs), and can be severely affected. In this paper we investigate the use of Artificial Neural Network (ANN) to overcome these effects and to provide a reliable damage detection method with a minimal of false indications. An experimental case of study (full scale pipe) is presented. Damages sizes have been increased and their shapes modified in different steps. Various parameters such as the number of inputs and the number of hidden neurons were studied to find the optimal configuration of the neural network.

  1. Trade-off between frequency and precision during stepping movements: Kinematic and BOLD brain activation patterns.

    Science.gov (United States)

    Martínez, Martin; Valencia, Miguel; Vidorreta, Marta; Luis, Elkin O; Castellanos, Gabriel; Villagra, Federico; Fernández-Seara, Maria A; Pastor, Maria A

    2016-05-01

    The central nervous system has the ability to adapt our locomotor pattern to produce a wide range of gait modalities and velocities. In reacting to external pacing stimuli, deviations from an individual preferred cadence provoke a concurrent decrease in accuracy that suggests the existence of a trade-off between frequency and precision; a compromise that could result from the specialization within the control centers of locomotion to ensure a stable transition and optimal adaptation to changing environment. Here, we explore the neural correlates of such adaptive mechanisms by visually guiding a group of healthy subjects to follow three comfortable stepping frequencies while simultaneously recording their BOLD responses and lower limb kinematics with the use of a custom-built treadmill device. In following the visual stimuli, subjects adopt a common pattern of symmetric and anti-phase movements across pace conditions. However, when increasing the stimulus frequency, an improvement in motor performance (precision and stability) was found, which suggests a change in the control mode from reactive to predictive schemes. Brain activity patterns showed similar BOLD responses across pace conditions though significant differences were observed in parietal and cerebellar regions. Neural correlates of stepping precision were found in the insula, cerebellum, dorsolateral pons and inferior olivary nucleus, whereas neural correlates of stepping stability were found in a distributed network, suggesting a transition in the control strategy across the stimulated range of frequencies: from unstable/reactive at lower paces (i.e., stepping stability managed by subcortical regions) to stable/predictive at higher paces (i.e., stability managed by cortical regions). Hum Brain Mapp 37:1722-1737, 2016. © 2016 Wiley Periodicals, Inc. PMID:26857613

  2. PRECISION RADIAL VELOCITIES WITH CSHELL

    International Nuclear Information System (INIS)

    Radial velocity (RV) identification of extrasolar planets has historically been dominated by optical surveys. Interest in expanding exoplanet searches to M dwarfs and young stars, however, has motivated a push to improve the precision of near-infrared RV techniques. We present our methodology for achieving 58 m s-1 precision in the K band on the M0 dwarf GJ 281 using the CSHELL spectrograph at the 3 m NASA Infrared Telescope Facility. We also demonstrate our ability to recover the known 4 MJUP exoplanet Gl 86 b and discuss the implications for success in detecting planets around 1-3 Myr old T Tauri stars.

  3. Precision protection through indirect correlations

    Science.gov (United States)

    Jin, Yao

    2016-04-01

    The dynamics of the quantum Fisher information of the parameters of the initial atomic state is studied, in the framework of open quantum systems, for a pair of static two-level atoms coupled to a bath of fluctuating vacuum scalar fields. Our results show that the correlations between the two atoms as well as the precision limit in quantum metrology are determined by the separation between the two atoms. Remarkably, when the separation between the two atoms approaches zero, the quantum Fisher information, thus the precision limit of the estimation of the parameters of the initial atomic state will be survived from the vacuum fluctuations after long time evolution.

  4. Sensing technologies for precision irrigation

    CERN Document Server

    Ćulibrk, Dubravko; Minic, Vladan; Alonso Fernandez, Marta; Alvarez Osuna, Javier; Crnojevic, Vladimir

    2014-01-01

    This brief provides an overview of state-of-the-art sensing technologies relevant to the problem of precision irrigation, an emerging field within the domain of precision agriculture. Applications of wireless sensor networks, satellite data and geographic information systems in the domain are covered. This brief presents the basic concepts of the technologies and emphasizes the practical aspects that enable the implementation of intelligent irrigation systems. The authors target a broad audience interested in this theme and organize the content in five chapters, each concerned with a specific technology needed to address the problem of optimal crop irrigation. Professionals and researchers will find the text a thorough survey with practical applications.

  5. A Hitchhiker’s Guide to Climate Change Leadership : An Educational Design Research exploration of a sustainability course at Uppsala University

    OpenAIRE

    May, Friederike

    2015-01-01

    Considering the ever-increasing impacts of climate change, the responsibility to take leadership lies with many actors; one of them being universities. The course in “Climate Change Leadership – Power, Politics and Culture” at CEMUS/Uppsala University explores the issue from a participatory perspective where students play a significant role in exploring what climate change leadership means throughout one semester. By using an educational design research approach this paper contributes to the ...

  6. Accelerator facilities users' guide

    International Nuclear Information System (INIS)

    In 1981 the ''Green Book'' of SIN was distributed, a User Handbook serving the needs of people already working at SIN as well as informing new users about our installations. An update of the Green Book is necessary because many beams have disappeared, been modified or added, and the installation has been upgraded in intensity and versatility quite considerably. The spectrum of users has shifted away from nuclear and particle physics; applications in medicine, solid state physics and materials science have gained in importance. This Users' Guide is intended to inform our users about the changes, and to interest potential new users in coming to PSI. (author) figs., tabs

  7. RTF Pocket Guide

    CERN Document Server

    Burke, Sean

    2008-01-01

    Rich Text Format, or RTF, is the internal markup language used by Microsoft Word and understood by dozens of other word processors. RTF is a universal file format that pervades practically every desktop. Because RTF is text, it's much easier to generate and process than binary .doc files. Any programmer working with word processing documents needs to learn enough RTF to get around, whether it's to format text for Word (or almost any other word processor), to make global changes to an existing document, or to convert Word files to (or from) another format. RTF Pocket Guide is a concise and e

  8. Improved Variational Guiding of Smoke Animations

    DEFF Research Database (Denmark)

    Nielsen, Michael Bang; Christensen, Brian Bunch

    2010-01-01

    Smoke animations are hard to art-direct because simple changes in parameters such as simulation resolution often lead to unpredictable changes in the final result. Previous work has addressed this problem with a guiding approach which couples low-resolution simulations - that exhibit the desired......, and employing time-dependent guiding is expensive because the matrix of the resulting set of equations needs to be recomputed at every iteration. We propose an improved mathematical model for Eulerianbased simulations which is better suited for dynamic, time-dependent guiding of smoke animations through a novel...... variational coupling of the low- and high-resolution simulations. Our model results in a matrix that does not require re-computation when the guiding changes over time, and hence we can employ time-dependent guiding more efficiently both in terms of storage and computational requirements. We demonstrate...

  9. Environment-assisted precision measurement

    DEFF Research Database (Denmark)

    Goldstein, G.; Cappellaro, P.; Maze, J. R.;

    2011-01-01

    We describe a method to enhance the sensitivity of precision measurements that takes advantage of the environment of a quantum sensor to amplify the response of the sensor to weak external perturbations. An individual qubit is used to sense the dynamics of surrounding ancillary qubits, which are in...

  10. Precision Measurements in Neutron Decay

    OpenAIRE

    Schumann, Marc; collaboration, for the PERKEO II

    2007-01-01

    We present new precision measurements of angular correlation coefficients in polarized neutron decay. We have obtained values for the electron asymmetry coefficient A, the neutrino asymmetry coefficient B, and for the proton asymmetry coefficient C. In combination with other results, the new measurements are used to derive limits on "Physics beyond the Standard Model".

  11. Sensor fusion for precision agriculture

    Science.gov (United States)

    Information-based management of crop production systems known as precision agriculture relies on different sensor technologies aimed at characterization of spatial heterogeneity of a cropping environment. Remote and proximal sensing systems have been deployed to obtain high-resolution data pertainin...

  12. Precise laser refractometry of liquids

    NARCIS (Netherlands)

    Gonchukov, S.; Vakurov, M.; Yermachenko, V.

    2006-01-01

    The results of development of two versions of the intracavity laser refractometry in reflection (ILRR) are reviewed in this paper. The ILRR method is based on the use of the properties of two-mode lasers with broken cavity and allows the precise refractive investigations of turbid media to be fulfil

  13. Spin and precision electroweak physics

    International Nuclear Information System (INIS)

    A perspective on fundamental parameters and precision tests of the Standard Model is given. Weak neutral current reactions are discussed with emphasis on those processes involving (polarized) electrons. The role of electroweak radiative corrections in determining the top quark mass and probing for ''new physics'' is described

  14. Precision Farming Tools. Yield Monitor

    OpenAIRE

    Grisso, Robert D. (Robert Dwight), 1956-; Alley, Mark M.; McClellan, Phil

    2005-01-01

    Using yield monitors is the first step many producers take in precision farming. A yield monitor, combined with Global Positioning System (GPS) technology, is an electronic tool that collects data on crop performance for a given year. To have accurate data for yield map interpretation, the yield monitor must be properly operated and calibrated.

  15. Precision Cleaning - Path to Premier

    Science.gov (United States)

    Mackler, Scott E.

    2008-01-01

    ITT Space Systems Division s new Precision Cleaning facility provides critical cleaning and packaging of aerospace flight hardware and optical payloads to meet customer performance requirements. The Precision Cleaning Path to Premier Project was a 2007 capital project and is a key element in the approved Premier Resource Management - Integrated Supply Chain Footprint Optimization Project. Formerly precision cleaning was located offsite in a leased building. A new facility equipped with modern precision cleaning equipment including advanced process analytical technology and improved capabilities was designed and built after outsourcing solutions were investigated and found lacking in ability to meet quality specifications and schedule needs. SSD cleans parts that can range in size from a single threaded fastener all the way up to large composite structures. Materials that can be processed include optics, composites, metals and various high performance coatings. We are required to provide verification to our customers that we have met their particulate and molecular cleanliness requirements and we have that analytical capability in this new facility. The new facility footprint is approximately half the size of the former leased operation and provides double the amount of throughput. Process improvements and new cleaning equipment are projected to increase 1st pass yield from 78% to 98% avoiding $300K+/yr in rework costs. Cost avoidance of $350K/yr will result from elimination of rent, IT services, transportation, and decreased utility costs. Savings due to reduced staff expected to net $4-500K/yr.

  16. A Review: The Role of Remote Sensing in Precision Agriculture

    Directory of Open Access Journals (Sweden)

    S. Liaghat

    2010-01-01

    Full Text Available Problem statement: Precision agriculture is an emerging farm management strategy that is changing the way people farm. Approach: At present, there is an increasing commitment to reduce reliance on excessive chemical inputs in agriculture. Numerous technologies have been applied to make agricultural products safer and to lower their adverse impacts on the environment, a goal that is consistent with sustainable agriculture. Results: Precision agriculture has emerged as a valuable component of the framework to achieve this goal. Conclusion: This review highlighted on remote sensing technology and describes how it can be used as an effective tool in precision agriculture.

  17. Motion and gravity effects in the precision of quantum clocks

    OpenAIRE

    Lindkvist, Joel; Sabín, Carlos; Johansson, Göran; Fuentes, Ivette

    2014-01-01

    We show that motion and gravity affect the precision of quantum clocks. We consider a localised quantum field as a fundamental model of a quantum clock moving in spacetime and show that its state is modified due to changes in acceleration. By computing the quantum Fisher information we determine how relativistic motion modifies the ultimate bound in the precision of the measurement of time. While in the absence of motion the squeezed vacuum is the ideal state for time estimation, we find that...

  18. Next generation informatics for big data in precision medicine era

    OpenAIRE

    Zhang, Yuji; Zhu, Qian; Liu, Hongfang

    2015-01-01

    The rise of data-intensive biology, advances in informatics technology, and changes in the way health care is delivered has created an compelling opportunity to allow us investigate biomedical questions in the context of “big data” and develop knowledge systems to support precision medicine. To promote such data mining and informatics technology development in precision medicine, we hosted two international informatics workshops in 2014: 1) the first workshop on Data Mining in Biomedical info...

  19. A Review: The Role of Remote Sensing in Precision Agriculture

    OpenAIRE

    S. Liaghat; S. K. Balasundram

    2010-01-01

    Problem statement: Precision agriculture is an emerging farm management strategy that is changing the way people farm. Approach: At present, there is an increasing commitment to reduce reliance on excessive chemical inputs in agriculture. Numerous technologies have been applied to make agricultural products safer and to lower their adverse impacts on the environment, a goal that is consistent with sustainable agriculture. Results: Precision agriculture has emerged as a valuable component of t...

  20. Mars Precision Entry Vehicle Guidance Using Internal Moving Mass Actuators

    OpenAIRE

    Atkins, Brad Matthew

    2014-01-01

    Many landing sites of scientific interest on Mars including most of the Southern Hemisphere at elevations above 2km Mars Orbiter Laser Altimeter reference are inaccessible due to current limitations in precision entry guidance and payload deceleration. Precision guidance and large payload deceleration is challenging due to the thin Martian atmosphere, large changes in free stream conditions during entry, and aerothermal and aerodynamic instability concerns associated with control systems with...

  1. An automatic registration method for frameless stereotaxy, image guided surgery, and enhanced reality visualization

    International Nuclear Information System (INIS)

    There is a need for frameless guidance systems to help surgeons plan the exact location for incisions, to define the margins of tumors, and to precisely identify locations of neighboring critical structures. The authors have developed an automatic technique for registering clinical data, such as segmented magnetic resonance imaging (MRI) or computed tomography (CT) reconstructions, with any view of the patient on the operating table. They demonstrate on the specific example of neurosurgery. The method enables a visual mix of live video of the patient and the segmented three-dimensional (3-D) MRI or CT model. This supports enhanced reality techniques for planning and guiding neurosurgical procedures and allows them to interactively view extracranial or intracranial structures nonintrusively. Extensions of the method include image guided biopsies, focused therapeutic procedures, and clinical studies involving change detection over time sequences of images

  2. Guide to Eating for Sports

    Medline Plus

    Full Text Available ... from Nemours for Parents for Kids for Teens Teens Home Body Mind Sexual Health Food & Fitness Diseases & Conditions Infections Q&A School & Jobs Drugs & Alcohol Staying Safe Recipes En Español Making a Change – ... for Sports KidsHealth > For Teens > A Guide to Eating for Sports Print A ...

  3. New insights into the QuikChangeTM process guide the use of Phusion DNA polymerase for site-directed mutagenesis

    OpenAIRE

    Xia, Yongzhen; Chu, Wenqiao; Qi, Qingsheng; Xun, Luying

    2014-01-01

    The QuikChangeTM site-directed mutagenesis method is popular but imperfect. An improvement by using partially overlapping primers has been reported several times; however, it is incompatible with the proposed mechanism. The QuikChangeTM method using complementary primers is proposed to linearly amplify a target plasmid with the products annealing to produce double-stranded DNA molecules with 5′-overhangs. The overhang annealing is supposed to form circular plasmids with staggered breaks, whic...

  4. NEW PRECISION PIEZOELECTRIC STEP ACTUATOR

    Institute of Scientific and Technical Information of China (English)

    LIU Jianfang; YANG Zhigang; FAN Zunqiang; CHENG Guangming

    2006-01-01

    A new precision piezoelectric actuator is proposed to improve its drive capabilities. The actuator is based on the piezoelectric technology. It adopts the principle of bionics and works with a new method of stator initiative anchoring/loosen and a distortion structure of double-side thin flexible hinge. It solves the problem of anchoring/loosen, frequency, journey, resolution and velocity. The experiment shows that the new linear piezoelectric actuator works with high frequency (100 Hz), high speed (502 μm/s), large travel (>10 mm), high resolution (0.05 μm) and high load (100 N). This kind of new piezoelectric actuator will be applied for large travel and high resolution driving device, optics engineering, precision positioning and some micromanipulation field.

  5. New librarianship field guide

    CERN Document Server

    Lankes, David R

    2016-01-01

    This book offers a guide for librarians who see their profession as a chance to make a positive difference in their communities -- librarians who recognize that it is no longer enough to stand behind a desk waiting to serve. R. David Lankes, author of "The Atlas of New Librarianship," reminds librarians of their mission: to improve society by facilitating knowledge creation in their communities. In this book, he provides tools, arguments, resources, and ideas for fulfilling this mission. Librarians will be prepared to become radical positive change agents in their communities, and other readers will learn to understand libraries in a new way. The librarians of Ferguson, Missouri, famously became positive change agents in August 2014 when they opened library doors when schools were closed because of civil unrest after the shooting of an unarmed teen by police. Working with other local organizations, they provided children and their parents a space for learning, lunch, and peace. But other libraries serve othe...

  6. Design of precise lightweight mirror

    Czech Academy of Sciences Publication Activity Database

    Vít, Tomáš; Melich, Radek; Václavík, Jan; Lédl, Vít

    Vol. 284-287. Zürich : Trans Tech Publications, 2013 - (Hsieh, W.), s. 2717-2722 ISSN 1660-9336. [International Conference on Engineering and Technology Innovation 2012 (ICETI 2012)/2./. Kaohsiung (TW), 02.11.2012-06.11.2012] R&D Projects: GA MŠk(CZ) ED2.1.00/03.0079 Institutional support: RVO:61389021 Keywords : SiSiC * lightweight mirrors * precise optics Subject RIV: JV - Space Technology

  7. Time-Precision Flexible Adder

    OpenAIRE

    García Chamizo, Juan Manuel; Mora Pascual, Jerónimo Manuel; Mora Mora, Higinio

    2003-01-01

    A new conception of flexible calculation that allows us to adjust a sum depending on the available time computation is presented. More specifically, the objective is to obtain a calculation model that makes the processing time/precision more flexible. The addition method is based on carry-select scheme adder and the proposed design uses precalculated data stored in look-up tables, which provide, above all, quality results and systematization in the implementation of low level primitives that ...

  8. Precision measurements in pionic hydrogen

    Energy Technology Data Exchange (ETDEWEB)

    Anagnostopoulos, D.F.; Cargnelli, M.; Fuhrmann, H.; Giersch, M.; Gotta, D.; Gruber, A.; Hennebach, M.; Hirtl, A.; Indelicato, P.; Liu, Y.W.; Manil, B.; Markushin, V.E.; Marton, J.; Nelms, N.; Simons, L.M.; Trasinelli, M.; Zmeskal, J

    2003-06-30

    The strong interaction in the pion nucleon system leads to a shift and a broadening of the 1s-ground state in pionic hydrogen. These two quantities are being measured in an experiment at the Paul Scherrer Institute with much improved precision and allow an experimental test of recent calculations in the framework of Chiral Perturbation Theory. The experimental techniques using high resolution crystal spectroscopy are described as well as recent results.

  9. Precision photometry for planetary transits

    CERN Document Server

    Pont, F; Pont, Frederic; Moutou, Claire

    2007-01-01

    We review the state of the art in follow-up photometry for planetary transit searches. Three topics are discussed: (1) Photometric monitoring of planets discovered by radial velocity to detect possible transits (2) Follow-up photometry of candidates from photometric transit searches to weed out eclipsing binaries and false positives (3) High-precision lightcurves of known transiting planets to increase the accuracy on the planet parameters.

  10. A Guide for Building Fit-For-Purpose Land Administration in Less Developed Countries: Capacity development, Change Management and Project Delivery

    DEFF Research Database (Denmark)

    McLaren, Robin; Enemark, Stig; Lemmen, Christiaan; Antonio, Danilo; Gitau, John

    2016-01-01

    Most less developed countries are struggling to find remedies for their many land problems that are often causing land conflicts, reducing economic development and preventing countries reaching their true potential. Existing investments in land administration have been built on legacy approaches...... and have not delivered the required pervasive changes and improvements at scale. Solutions have not helped the poor and disadvantaged that have no security of tenure. In fact the beneficiaries have often been the elite and organizations involved in land grabbing. It is time to rethink the approaches...... approaches and issues associated with implementing FFP land administration, including change management, capacity development and project delivery....

  11. A simple guide to Skype

    CERN Document Server

    Winter, Rick

    2012-01-01

    Readers will hit the ground running with this concise guide to Skype. The book explains basics such as how to set up an account and how to add friends, family, and other contacts. It also discusses some of the program's more advanced features, such as how to change views, set a particular status, and conduct video and audio-only calls. Readers learn how to parlay the benefits of this free service to stay in touch with personal and business contacts with this easy guide.

  12. Global Social Media Directory: A Resource Guide

    Energy Technology Data Exchange (ETDEWEB)

    Noonan, Christine F.; Piatt, Andrew W.

    2014-10-23

    The Global Social Media Directory is a resource guide providing information on social networking services around the globe. This information changes rapidly, therefore, this document will be updated on a regular basis and as funding permits.

  13. Precision and Accuracy Parameters in Structured Light 3-D Scanning

    Science.gov (United States)

    Eiríksson, E. R.; Wilm, J.; Pedersen, D. B.; Aanæs, H.

    2016-04-01

    Structured light systems are popular in part because they can be constructed from off-the-shelf low cost components. In this paper we quantitatively show how common design parameters affect precision and accuracy in such systems, supplying a much needed guide for practitioners. Our quantitative measure is the established VDI/VDE 2634 (Part 2) guideline using precision made calibration artifacts. Experiments are performed on our own structured light setup, consisting of two cameras and a projector. We place our focus on the influence of calibration design parameters, the calibration procedure and encoding strategy and present our findings. Finally, we compare our setup to a state of the art metrology grade commercial scanner. Our results show that comparable, and in some cases better, results can be obtained using the parameter settings determined in this study.

  14. Autonomous Guided Car Using a Fuzzy Controller

    OpenAIRE

    Olivares Mendez, Miguel Angel; Campoy, Pascual; Mellado-Bataller, Ignacio; Mondragon, Ivan; Martinez, Carol; Sanchez-Lopez, Joseluis

    2013-01-01

    The goal of the work described in this paper is to develop a visual line guided system for being used on-board an Autonomous Guided Vehicle (AGV) commercial car, controlling the steering and using just the visual information of a line painted below the car. In order to implement the control of the vehicle, a Fuzzy Logic controller has been implemented, that has to be robust against curvature changes and velocity changes. The only input information for the controller is th...

  15. 4 NCIC Data Acquisition Guide

    Science.gov (United States)

    U.S. Geological Survey

    1979-01-01

    The National Cartographic Information Center (NCIC) is the information branch of the National Mapping Program. NCIC gathers descriptions of cartographic products held by Federal, State and local agencies, and private companies. Computerized information systems are used to edit, store, and distribute these descriptions. The Aerial Photography Summary Record System (APSRS) is NCIC's system for determining if photographs of a particular area, with a particular set of characteristics, are available, and if so, where they can be found. This guide defines the procedures for planning and conducting visits to potential contributors to the APSRS data base. The guide also defines acquisition responsibilities of the contributor, State affiliates, mapping centers, and NCIC headquarters. As a Data Acquisition specialist, you are encouraged to seek innovative approaches to acquiring data and to suggest additions or changes to this guide.

  16. Guiding Principles for Building Fit-For-Purpose Land Administration Systems in Developing Countries: Capacity Development, Change Management and Project Delivery

    OpenAIRE

    McLaren, Robin; Enemark, Stig; Lemmen, Christiaan

    2016-01-01

    Most developing countries are struggling to find remedies for their many land problems that are often causing land conflicts, reducing economic development and preventing countries reaching their true potential. Existing investments in land administration have been built on legacy approaches and have not delivered the required pervasive changes and improvements at scale. Solutions have not helped the poor and disadvantaged that have no security of tenure. In fact the beneficiaries have often ...

  17. Short-term learning of a visually guided power-grip task is associated with dynamic changes in EEG oscillatory activity

    OpenAIRE

    Kranczioch, C.; Athanassiou, S.; Shen, S; G. Gao; A. Sterr

    2008-01-01

    Objective: Performing a motor task after a period of training has been associated with reduced cortical activity and changes in oscillatory brain activity. Little is known about whether learning also affects the neural network associated with motor preparation and post movement processes. Here we investigate how short-term motor learning affects oscillatory brain activity during the preparation, execution, and post-movement stage of a force-feedback task. Methods: Participants performed a vis...

  18. Precision luminosity measurement at ILC

    CERN Document Server

    Bozovic-Jelisavcic, I; Pandurovic, M; Smiljanic, I

    2014-01-01

    In these proceedings a novel approach to deal with the beam-induced effects in luminosity measurement is presented. Based on the relativistic kinematics of the collision frame of the Bhabha process, the beam-beam related uncertainties can be reduced to the permille level independently of a precision with which the beam parameters are known. Specific event selection combined with the corrective methods we introduce, leads to the systematic uncertainty from the beam-induced effects to be at a few permille level in the peak region above the 80% of the nominal centre-of-mass energies at ILC.

  19. High precision anatomy for MEG

    OpenAIRE

    Troebinger, Luzia; López, José David; Lutti, Antoine; Bradbury, David; Bestmann, Sven; Barnes, Gareth

    2013-01-01

    Precise MEG estimates of neuronal current flow are undermined by uncertain knowledge of the head location with respect to the MEG sensors. This is either due to head movements within the scanning session or systematic errors in co-registration to anatomy. Here we show how such errors can be minimized using subject-specific head-casts produced using 3D printing technology. The casts fit the scalp of the subject internally and the inside of the MEG dewar externally, reducing within session and ...

  20. Making evaluations matter: a practical guide for evaluators

    OpenAIRE

    Kusters, C.S.L.; Vugt, van, M.; Wigboldus, S.A.; Williams, B; Woodhill, A.J.

    2011-01-01

    This guide is primarily for evaluators working in the international development sector. It is also useful for commissioner of evaluations, evaluation managers and M&E officers. The guide explains how to make evaluations more useful. It helps to better understand conceptual issues and appreciate how evaluations can contribute to changing mindsets and empowering stakeholders. On a practical level, the guide presents core guiding principles and pointers on how to design and facilitate evalua...

  1. Development of a data acquisition and processing system for precision agriculture

    Science.gov (United States)

    A data acquisition and processing system for precision agriculture was developed by using MapX5.0 and Visual C 6.0. This system can be used easily and quickly for drawing grid maps in-field, creating parameters for grid-reorganization, guiding in-field data collection, converting data between diffe...

  2. Software for precise tracking of cell proliferation

    Energy Technology Data Exchange (ETDEWEB)

    Kurokawa, Hiroshi [Brain Science Institute, RIKEN, 2-1 Hirosawa, Wako-city, Saitama 351-0198 (Japan); School of Life Science, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392 (Japan); Noda, Hisayori [Brain Science Institute, RIKEN, 2-1 Hirosawa, Wako-city, Saitama 351-0198 (Japan); Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550 (Japan); Sugiyama, Mayu [Brain Science Institute, RIKEN, 2-1 Hirosawa, Wako-city, Saitama 351-0198 (Japan); School of Life Science, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392 (Japan); Sakaue-Sawano, Asako [Brain Science Institute, RIKEN, 2-1 Hirosawa, Wako-city, Saitama 351-0198 (Japan); Life Function and Dynamics, ERATO, JST, 2-1 Hirosawa, Wako-city, Saitama 351-0198 (Japan); Fukami, Kiyoko [School of Life Science, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392 (Japan); Miyawaki, Atsushi, E-mail: matsushi@brain.riken.jp [Brain Science Institute, RIKEN, 2-1 Hirosawa, Wako-city, Saitama 351-0198 (Japan); Life Function and Dynamics, ERATO, JST, 2-1 Hirosawa, Wako-city, Saitama 351-0198 (Japan)

    2012-01-20

    Highlights: Black-Right-Pointing-Pointer We developed software for analyzing cultured cells that divide as well as migrate. Black-Right-Pointing-Pointer The active contour model (Snakes) was used as the core algorithm. Black-Right-Pointing-Pointer The time backward analysis was also used for efficient detection of cell division. Black-Right-Pointing-Pointer With user-interactive correction functions, the software enables precise tracking. Black-Right-Pointing-Pointer The software was successfully applied to cells with fluorescently-labeled nuclei. -- Abstract: We have developed a multi-target cell tracking program TADOR, which we applied to a series of fluorescence images. TADOR is based on an active contour model that is modified in order to be free of the problem of locally optimal solutions, and thus is resistant to signal fluctuation and morphological changes. Due to adoption of backward tracing and addition of user-interactive correction functions, TADOR is used in an off-line and semi-automated mode, but enables precise tracking of cell division. By applying TADOR to the analysis of cultured cells whose nuclei had been fluorescently labeled, we tracked cell division and cell-cycle progression on coverslips over an extended period of time.

  3. Software for precise tracking of cell proliferation

    International Nuclear Information System (INIS)

    Highlights: ► We developed software for analyzing cultured cells that divide as well as migrate. ► The active contour model (Snakes) was used as the core algorithm. ► The time backward analysis was also used for efficient detection of cell division. ► With user-interactive correction functions, the software enables precise tracking. ► The software was successfully applied to cells with fluorescently-labeled nuclei. -- Abstract: We have developed a multi-target cell tracking program TADOR, which we applied to a series of fluorescence images. TADOR is based on an active contour model that is modified in order to be free of the problem of locally optimal solutions, and thus is resistant to signal fluctuation and morphological changes. Due to adoption of backward tracing and addition of user-interactive correction functions, TADOR is used in an off-line and semi-automated mode, but enables precise tracking of cell division. By applying TADOR to the analysis of cultured cells whose nuclei had been fluorescently labeled, we tracked cell division and cell-cycle progression on coverslips over an extended period of time.

  4. 3D-printed guiding templates for improved osteosarcoma resection

    Science.gov (United States)

    Ma, Limin; Zhou, Ye; Zhu, Ye; Lin, Zefeng; Wang, Yingjun; Zhang, Yu; Xia, Hong; Mao, Chuanbin

    2016-03-01

    Osteosarcoma resection is challenging due to the variable location of tumors and their proximity with surrounding tissues. It also carries a high risk of postoperative complications. To overcome the challenge in precise osteosarcoma resection, computer-aided design (CAD) was used to design patient-specific guiding templates for osteosarcoma resection on the basis of the computer tomography (CT) scan and magnetic resonance imaging (MRI) of the osteosarcoma of human patients. Then 3D printing technique was used to fabricate the guiding templates. The guiding templates were used to guide the osteosarcoma surgery, leading to more precise resection of the tumorous bone and the implantation of the bone implants, less blood loss, shorter operation time and reduced radiation exposure during the operation. Follow-up studies show that the patients recovered well to reach a mean Musculoskeletal Tumor Society score of 27.125.

  5. PRECISION ATTACHMENTS; APPLICATIONS AND LIMITATIONS

    Directory of Open Access Journals (Sweden)

    Prabhakar

    2012-12-01

    Full Text Available ABSTRACT: A unique concern of a removable denture when compare d to others is retention. Retention is the ability of the prosthesis to resist the movement of denture away from the supporting tissues/teeth. The component of removable d enture which provides retention is called as direct retainer. 1,3,4 A direct retainer can be either an extracoronal or intracoronal retainer. Extracoronal direct retainer uses mechanical resistance to displa cement through components placed on external surface of abutment teeth. Intracoronal retainer is either cast or attached to tally within the restored natural contours of an abutment tooth. 1 One of the main drawbacks of extracoronal retainers used in partial dentures is visibility. Many patients find themselves in an aest hetically compromised state when these retainers are placed on teeth in visible area. Preci sion attachments provide solution for this problem. Also, precision attachments provide better ve rtical support and better stimulation to the underlying tissue through intermittent vertical massage. 1,9 Although the history of intracoronal retainers goes back to 5 th and 4 th centuries BC, technically more sound developments began in early 2 0 th century AD, with Dr. Herman E. S. Chayes formulating the principle of internal attachme nt in 1906. Since then precision attachments are playing an important role in removabl e and fixed partial denture, conventional and implant supported overdenture. 9

  6. Precision experiments in electroweak interactions

    International Nuclear Information System (INIS)

    The electroweak theory of Glashow, Weinberg, and Salam (GWS) has become one of the twin pillars upon which our understanding of all particle physics phenomena rests. It is a brilliant achievement that qualitatively and quantitatively describes all of the vast quantity of experimental data that have been accumulated over some forty years. Note that the word quantitatively must be qualified. The low energy limiting cases of the GWS theory, Quantum Electrodynamics and the V-A Theory of Weak Interactions, have withstood rigorous testing. The high energy synthesis of these ideas, the GWS theory, has not yet been subjected to comparably precise scrutiny. The recent operation of a new generation of proton-antiproton (p bar p) and electron-positron (e+e-) colliders has made it possible to produce and study large samples of the electroweak gauge bosons W± and Z0. We expect that these facilities will enable very precise tests of the GWS theory to be performed in the near future. In keeping with the theme of this Institute, Physics at the 100 GeV Mass Scale, these lectures will explore the current status and the near-future prospects of these experiments

  7. Green Solvents for Precision Cleaning

    Science.gov (United States)

    Grandelli, Heather; Maloney, Phillip; DeVor, Robert; Surma, Jan; Hintze, Paul

    2013-01-01

    Aerospace machinery used in liquid oxygen (LOX) fuel systems must be precision cleaned to achieve a very low level of non-volatile residue (solvent-replacement is non-flammable, environmentally benign, non-corrosive, inexpensive, effective and evaporates completely, leaving no residue. Highlighted is a green precision cleaning process, which is contaminant removal using supercritical carbon dioxide as the environmentally benign solvent. In this process, the contaminant is dissolved in carbon dioxide, and the parts are recovered at the end of the cleaning process completely dry and ready for use. Typical contaminants of aerospace components include hydrocarbon greases, hydraulic fluids, silicone fluids and greases, fluorocarbon fluids and greases and fingerprint oil. Metallic aerospace components range from small nuts and bolts to much larger parts, such as butterfly valves 18 in diameter. A fluorinated grease, Krytox, is investigated as a model contaminant in these preliminary studies, and aluminum coupons are employed as a model aerospace component. Preliminary studies are presented in which the experimental parameters are optimized for removal of Krytox from aluminum coupons in a stirred-batch process. The experimental conditions investigated are temperature, pressure, exposure time and impeller speed. Temperatures of 308 - 423 K, pressures in the range of 8.3 - 41.4 MPa, exposure times between 5 - 60 min and impeller speeds of 0 - 1000 rpm were investigated. Preliminary results showed up to 86 cleaning efficiency with the moderate processing conditions of 323 K, 13.8 MPa, 30 min and 750 rpm.

  8. Precision luminosity measurements at LHCb

    CERN Document Server

    Aaij, Roel; Adinolfi, Marco; Affolder, Anthony; Ajaltouni, Ziad; Akar, Simon; Albrecht, Johannes; Alessio, Federico; Alexander, Michael; Ali, Suvayu; Alkhazov, Georgy; Alvarez Cartelle, Paula; Alves Jr, Antonio Augusto; Amato, Sandra; Amerio, Silvia; Amhis, Yasmine; An, Liupan; Anderlini, Lucio; Anderson, Jonathan; Andreassen, Rolf; Andreotti, Mirco; Andrews, Jason; Appleby, Robert; Aquines Gutierrez, Osvaldo; Archilli, Flavio; Artamonov, Alexander; Artuso, Marina; Aslanides, Elie; Auriemma, Giulio; Baalouch, Marouen; Bachmann, Sebastian; Back, John; Badalov, Alexey; Baesso, Clarissa; Baldini, Wander; Barlow, Roger; Barschel, Colin; Barsuk, Sergey; Barter, William; Batozskaya, Varvara; Battista, Vincenzo; Bay, Aurelio; Beaucourt, Leo; Beddow, John; Bedeschi, Franco; Bediaga, Ignacio; Belogurov, Sergey; Belous, Konstantin; Belyaev, Ivan; Ben-Haim, Eli; Bencivenni, Giovanni; Benson, Sean; Benton, Jack; Berezhnoy, Alexander; Bernet, Roland; Bettler, Marc-Olivier; van Beuzekom, Martinus; Bien, Alexander; Bifani, Simone; Bird, Thomas; Bizzeti, Andrea; Bjørnstad, Pål Marius; Blake, Thomas; Blanc, Frédéric; Blouw, Johan; Blusk, Steven; Bocci, Valerio; Bondar, Alexander; Bondar, Nikolay; Bonivento, Walter; Borghi, Silvia; Borgia, Alessandra; Borsato, Martino; Bowcock, Themistocles; Bowen, Espen Eie; Bozzi, Concezio; Brambach, Tobias; Bressieux, Joël; Brett, David; Britsch, Markward; Britton, Thomas; Brodzicka, Jolanta; Brook, Nicholas; Brown, Henry; Bursche, Albert; Buytaert, Jan; Cadeddu, Sandro; Calabrese, Roberto; Calvi, Marta; Calvo Gomez, Miriam; Campana, Pierluigi; Campora Perez, Daniel; Carbone, Angelo; Carboni, Giovanni; Cardinale, Roberta; Cardini, Alessandro; Carson, Laurence; Carvalho Akiba, Kazuyoshi; Casse, Gianluigi; Cassina, Lorenzo; Castillo Garcia, Lucia; Cattaneo, Marco; Cauet, Christophe; Cenci, Riccardo; Charles, Matthew; Charpentier, Philippe; Chefdeville, Maximilien; Chen, Shanzhen; Cheung, Shu-Faye; Chiapolini, Nicola; Chrzaszcz, Marcin; Ciba, Krzystof; Cid Vidal, Xabier; Ciezarek, Gregory; Clarke, Peter; Clemencic, Marco; Cliff, Harry; Closier, Joel; Coco, Victor; Cogan, Julien; Cogneras, Eric; Cojocariu, Lucian; Collazuol, Gianmaria; Collins, Paula; Comerma-Montells, Albert; Contu, Andrea; Cook, Andrew; Coombes, Matthew; Coquereau, Samuel; Corti, Gloria; Corvo, Marco; Counts, Ian; Couturier, Benjamin; Cowan, Greig; Craik, Daniel Charles; Cruz Torres, Melissa Maria; Cunliffe, Samuel; Currie, Robert; D'Ambrosio, Carmelo; Dalseno, Jeremy; David, Pascal; David, Pieter; Davis, Adam; De Bruyn, Kristof; De Capua, Stefano; De Cian, Michel; De Miranda, Jussara; De Paula, Leandro; De Silva, Weeraddana; De Simone, Patrizia; Dean, Cameron Thomas; Decamp, Daniel; Deckenhoff, Mirko; Del Buono, Luigi; Déléage, Nicolas; Derkach, Denis; Deschamps, Olivier; Dettori, Francesco; Di Canto, Angelo; Dijkstra, Hans; Donleavy, Stephanie; Dordei, Francesca; Dorigo, Mirco; Dosil Suárez, Alvaro; Dossett, David; Dovbnya, Anatoliy; Dreimanis, Karlis; Dujany, Giulio; Dupertuis, Frederic; Durante, Paolo; Dzhelyadin, Rustem; Dziurda, Agnieszka; Dzyuba, Alexey; Easo, Sajan; Egede, Ulrik; Egorychev, Victor; Eidelman, Semen; Eisenhardt, Stephan; Eitschberger, Ulrich; Ekelhof, Robert; Eklund, Lars; El Rifai, Ibrahim; Elsasser, Christian; Ely, Scott; Esen, Sevda; Evans, Hannah Mary; Evans, Timothy; Falabella, Antonio; Färber, Christian; Farinelli, Chiara; Farley, Nathanael; Farry, Stephen; Fay, Robert; Ferguson, Dianne; Fernandez Albor, Victor; Ferreira Rodrigues, Fernando; Ferro-Luzzi, Massimiliano; Filippov, Sergey; Fiore, Marco; Fiorini, Massimiliano; Firlej, Miroslaw; Fitzpatrick, Conor; Fiutowski, Tomasz; Fol, Philip; Fontana, Marianna; Fontanelli, Flavio; Forty, Roger; Francisco, Oscar; Frank, Markus; Frei, Christoph; Frosini, Maddalena; Fu, Jinlin; Furfaro, Emiliano; Gallas Torreira, Abraham; Galli, Domenico; Gallorini, Stefano; Gambetta, Silvia; Gandelman, Miriam; Gandini, Paolo; Gao, Yuanning; García Pardiñas, Julián; Garofoli, Justin; Garra Tico, Jordi; Garrido, Lluis; Gascon, David; Gaspar, Clara; Gauld, Rhorry; Gavardi, Laura; Geraci, Angelo; Gersabeck, Evelina; Gersabeck, Marco; Gershon, Timothy; Ghez, Philippe; Gianelle, Alessio; Gianì, Sebastiana; Gibson, Valerie; Giubega, Lavinia-Helena; Gligorov, Vladimir; Göbel, Carla; Golubkov, Dmitry; Golutvin, Andrey; Gomes, Alvaro; Gotti, Claudio; Grabalosa Gándara, Marc; Graciani Diaz, Ricardo; Granado Cardoso, Luis Alberto; Graugés, Eugeni; Graziani, Giacomo; Grecu, Alexandru; Greening, Edward; Gregson, Sam; Griffith, Peter; Grillo, Lucia; Grünberg, Oliver; Gui, Bin; Gushchin, Evgeny; Guz, Yury; Gys, Thierry; Hadjivasiliou, Christos; Haefeli, Guido; Haen, Christophe; Haines, Susan; Hall, Samuel; Hamilton, Brian; Hampson, Thomas; Han, Xiaoxue; Hansmann-Menzemer, Stephanie; Harnew, Neville; Harnew, Samuel; Harrison, Jonathan; He, Jibo; Head, Timothy; Heijne, Veerle; Hennessy, Karol; Henrard, Pierre; Henry, Louis; Hernando Morata, Jose Angel; van Herwijnen, Eric; Heß, Miriam; Hicheur, Adlène; Hill, Donal; Hoballah, Mostafa; Hombach, Christoph; Hulsbergen, Wouter; Hunt, Philip; Hussain, Nazim; Hutchcroft, David; Hynds, Daniel; Idzik, Marek; Ilten, Philip; Jacobsson, Richard; Jaeger, Andreas; Jalocha, Pawel; Jans, Eddy; Jaton, Pierre; Jawahery, Abolhassan; Jing, Fanfan; John, Malcolm; Johnson, Daniel; Jones, Christopher; Joram, Christian; Jost, Beat; Jurik, Nathan; Kandybei, Sergii; Kanso, Walaa; Karacson, Matthias; Karbach, Moritz; Karodia, Sarah; Kelsey, Matthew; Kenyon, Ian; Ketel, Tjeerd; Khanji, Basem; Khurewathanakul, Chitsanu; Klaver, Suzanne; Klimaszewski, Konrad; Kochebina, Olga; Kolpin, Michael; Komarov, Ilya; Koopman, Rose; Koppenburg, Patrick; Korolev, Mikhail; Kozlinskiy, Alexandr; Kravchuk, Leonid; Kreplin, Katharina; Kreps, Michal; Krocker, Georg; Krokovny, Pavel; Kruse, Florian; Kucewicz, Wojciech; Kucharczyk, Marcin; Kudryavtsev, Vasily; Kurek, Krzysztof; Kvaratskheliya, Tengiz; La Thi, Viet Nga; Lacarrere, Daniel; Lafferty, George; Lai, Adriano; Lambert, Dean; Lambert, Robert W; Lanfranchi, Gaia; Langenbruch, Christoph; Langhans, Benedikt; Latham, Thomas; Lazzeroni, Cristina; Le Gac, Renaud; van Leerdam, Jeroen; Lees, Jean-Pierre; Lefèvre, Regis; Leflat, Alexander; Lefrançois, Jacques; Leo, Sabato; Leroy, Olivier; Lesiak, Tadeusz; Leverington, Blake; Li, Yiming; Likhomanenko, Tatiana; Liles, Myfanwy; Lindner, Rolf; Linn, Christian; Lionetto, Federica; Liu, Bo; Lohn, Stefan; Longstaff, Iain; Lopes, Jose; Lopez-March, Neus; Lowdon, Peter; Lu, Haiting; Lucchesi, Donatella; Luo, Haofei; Lupato, Anna; Luppi, Eleonora; Lupton, Oliver; Machefert, Frederic; Machikhiliyan, Irina V; Maciuc, Florin; Maev, Oleg; Malde, Sneha; Malinin, Alexander; Manca, Giulia; Mancinelli, Giampiero; Mapelli, Alessandro; Maratas, Jan; Marchand, Jean François; Marconi, Umberto; Marin Benito, Carla; Marino, Pietro; Märki, Raphael; Marks, Jörg; Martellotti, Giuseppe; Martens, Aurelien; Martín Sánchez, Alexandra; Martinelli, Maurizio; Martinez Santos, Diego; Martinez Vidal, Fernando; Martins Tostes, Danielle; Massafferri, André; Matev, Rosen; Mathe, Zoltan; Matteuzzi, Clara; Maurin, Brice; Mazurov, Alexander; McCann, Michael; McCarthy, James; McNab, Andrew; McNulty, Ronan; McSkelly, Ben; Meadows, Brian; Meier, Frank; Meissner, Marco; Merk, Marcel; Milanes, Diego Alejandro; Minard, Marie-Noelle; Moggi, Niccolò; Molina Rodriguez, Josue; Monteil, Stephane; Morandin, Mauro; Morawski, Piotr; Mordà, Alessandro; Morello, Michael Joseph; Moron, Jakub; Morris, Adam Benjamin; Mountain, Raymond; Muheim, Franz; Müller, Katharina; Mussini, Manuel; Muster, Bastien; Naik, Paras; Nakada, Tatsuya; Nandakumar, Raja; Nasteva, Irina; Needham, Matthew; Neri, Nicola; Neubert, Sebastian; Neufeld, Niko; Neuner, Max; Nguyen, Anh Duc; Nguyen, Thi-Dung; Nguyen-Mau, Chung; Nicol, Michelle; Niess, Valentin; Niet, Ramon; Nikitin, Nikolay; Nikodem, Thomas; Novoselov, Alexey; O'Hanlon, Daniel Patrick; Oblakowska-Mucha, Agnieszka; Obraztsov, Vladimir; Oggero, Serena; Ogilvy, Stephen; Okhrimenko, Oleksandr; Oldeman, Rudolf; Onderwater, Gerco; Orlandea, Marius; Otalora Goicochea, Juan Martin; Owen, Patrick; Oyanguren, Maria Arantza; Pal, Bilas Kanti; Palano, Antimo; Palombo, Fernando; Palutan, Matteo; Panman, Jacob; Papanestis, Antonios; Pappagallo, Marco; Pappalardo, Luciano; Parkes, Christopher; Parkinson, Christopher John; Passaleva, Giovanni; Patel, Girish; Patel, Mitesh; Patrignani, Claudia; Pearce, Alex; Pellegrino, Antonio; Pepe Altarelli, Monica; Perazzini, Stefano; Perret, Pascal; Perrin-Terrin, Mathieu; Pescatore, Luca; Pesen, Erhan; Pessina, Gianluigi; Petridis, Konstantin; Petrolini, Alessandro; Picatoste Olloqui, Eduardo; Pietrzyk, Boleslaw; Pilař, Tomas; Pinci, Davide; Pistone, Alessandro; Playfer, Stephen; Plo Casasus, Maximo; Polci, Francesco; Poluektov, Anton; Polycarpo, Erica; Popov, Alexander; Popov, Dmitry; Popovici, Bogdan; Potterat, Cédric; Price, Eugenia; Price, Joseph David; Prisciandaro, Jessica; Pritchard, Adrian; Prouve, Claire; Pugatch, Valery; Puig Navarro, Albert; Punzi, Giovanni; Qian, Wenbin; Rachwal, Bartolomiej; Rademacker, Jonas; Rakotomiaramanana, Barinjaka; Rama, Matteo; Rangel, Murilo; Raniuk, Iurii; Rauschmayr, Nathalie; Raven, Gerhard; Redi, Federico; Reichert, Stefanie; Reid, Matthew; dos Reis, Alberto; Ricciardi, Stefania; Richards, Sophie; Rihl, Mariana; Rinnert, Kurt; Rives Molina, Vincente; Robbe, Patrick; Rodrigues, Ana Barbara; Rodrigues, Eduardo; Rodriguez Perez, Pablo; Roiser, Stefan; Romanovsky, Vladimir; Romero Vidal, Antonio; Rotondo, Marcello; Rouvinet, Julien; Ruf, Thomas; Ruiz, Hugo; Ruiz Valls, Pablo; Saborido Silva, Juan Jose; Sagidova, Naylya; Sail, Paul; Saitta, Biagio; Salustino Guimaraes, Valdir; Sanchez Mayordomo, Carlos; Sanmartin Sedes, Brais; Santacesaria, Roberta; Santamarina Rios, Cibran; Santovetti, Emanuele; Sarti, Alessio; Satriano, Celestina; Satta, Alessia; Saunders, Daniel Martin; Savrina, Darya; Schiller, Manuel; Schindler, Heinrich; Schlupp, Maximilian; Schmelling, Michael; Schmidt, Burkhard; Schneider, Olivier; Schopper, Andreas; Schubiger, Maxime; Schune, Marie Helene; Schwemmer, Rainer; Sciascia, Barbara; Sciubba, Adalberto; Semennikov, Alexander; Sepp, Indrek; Serra, Nicola; Serrano, Justine; Sestini, Lorenzo; Seyfert, Paul; Shapkin, Mikhail; Shapoval, Illya; Shcheglov, Yury; Shears, Tara; Shekhtman, Lev; Shevchenko, Vladimir; Shires, Alexander; Silva Coutinho, Rafael; Simi, Gabriele; Sirendi, Marek; Skidmore, Nicola; Skwarnicki, Tomasz; Smith, Anthony; Smith, Edmund; Smith, Eluned; Smith, Jackson; Smith, Mark; Snoek, Hella; Sokoloff, Michael; Soler, Paul; Soomro, Fatima; Souza, Daniel; Souza De Paula, Bruno; Spaan, Bernhard; Sparkes, Ailsa; Spradlin, Patrick; Sridharan, Srikanth; Stagni, Federico; Stahl, Marian; Stahl, Sascha; Steinkamp, Olaf; Stenyakin, Oleg; Stevenson, Scott; Stoica, Sabin; Stone, Sheldon; Storaci, Barbara; Stracka, Simone; Straticiuc, Mihai; Straumann, Ulrich; Stroili, Roberto; Subbiah, Vijay Kartik; Sun, Liang; Sutcliffe, William; Swientek, Krzysztof; Swientek, Stefan; Syropoulos, Vasileios; Szczekowski, Marek; Szczypka, Paul; Szumlak, Tomasz; T'Jampens, Stephane; Teklishyn, Maksym; Tellarini, Giulia; Teubert, Frederic; Thomas, Christopher; Thomas, Eric; van Tilburg, Jeroen; Tisserand, Vincent; Tobin, Mark; Tolk, Siim; Tomassetti, Luca; Tonelli, Diego; Topp-Joergensen, Stig; Torr, Nicholas; Tournefier, Edwige; Tourneur, Stephane; Tran, Minh Tâm; Tresch, Marco; Trisovic, Ana; Tsaregorodtsev, Andrei; Tsopelas, Panagiotis; Tuning, Niels; Ubeda Garcia, Mario; Ukleja, Artur; Ustyuzhanin, Andrey; Uwer, Ulrich; Vacca, Claudia; Vagnoni, Vincenzo; Valenti, Giovanni; Vallier, Alexis; Vazquez Gomez, Ricardo; Vazquez Regueiro, Pablo; Vázquez Sierra, Carlos; Vecchi, Stefania; Velthuis, Jaap; Veltri, Michele; Veneziano, Giovanni; Vesterinen, Mika; Viaud, Benoit; Vieira, Daniel; Vieites Diaz, Maria; Vilasis-Cardona, Xavier; Vollhardt, Achim; Volyanskyy, Dmytro; Voong, David; Vorobyev, Alexey; Vorobyev, Vitaly; Voß, Christian; de Vries, Jacco; Waldi, Roland; Wallace, Charlotte; Wallace, Ronan; Walsh, John; Wandernoth, Sebastian; Wang, Jianchun; Ward, David; Watson, Nigel; Websdale, David; Whitehead, Mark; Wicht, Jean; Wiedner, Dirk; Wilkinson, Guy; Williams, Matthew; Williams, Mike; Wilschut, Hans; Wilson, Fergus; Wimberley, Jack; Wishahi, Julian; Wislicki, Wojciech; Witek, Mariusz; Wormser, Guy; Wotton, Stephen; Wright, Simon; Wyllie, Kenneth; Xie, Yuehong; Xing, Zhou; Xu, Zhirui; Yang, Zhenwei; Yuan, Xuhao; Yushchenko, Oleg; Zangoli, Maria; Zavertyaev, Mikhail; Zhang, Liming; Zhang, Wen Chao; Zhang, Yanxi; Zhelezov, Alexey; Zhokhov, Anatoly; Zhong, Liang; Zvyagin, Alexander

    2014-01-01

    Measuring cross-sections at the LHC requires the luminosity to be determined accurately at each centre-of-mass energy $\\sqrt{s}$. In this paper results are reported from the luminosity calibrations carried out at the LHC interaction point 8 with the LHCb detector for $\\sqrt{s}$ = 2.76, 7 and 8 TeV (proton-proton collisions) and for $\\sqrt{s_{NN}}$ = 5 TeV (proton-lead collisions). Both the "van der Meer scan" and "beam-gas imaging" luminosity calibration methods were employed. It is observed that the beam density profile cannot always be described by a function that is factorizable in the two transverse coordinates. The introduction of a two-dimensional description of the beams improves significantly the consistency of the results. For proton-proton interactions at $\\sqrt{s}$ = 8 TeV a relative precision of the luminosity calibration of 1.47% is obtained using van der Meer scans and 1.43% using beam-gas imaging, resulting in a combined precision of 1.12%. Applying the calibration to the full data set determin...

  9. DESIGN OF FARMLAND GIS FOR PRECISION AGRICULTURE

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Precision Agriculture, also known as Precision Farming, or Prescription Farming, is a modern agriculture technology system, which brings " precision" into agriculture system. All concepts of Precision Agriculture are established on the collection and management of variable cropland information. As the tool of collecting, managing and analyzing spatial data, GIS is the key technology of integrated Precision Agriculture system. This article puts forward the concept of Farmland GIS and designs Farmland GIS into five modules, and specifies the functions of the each module, which builds the foundation for practical development of the software. The study and development of Farmland GIS will propel the spreading of Precision Agriculture technology in China.

  10. Investigation of Changes in the Microscopic Structure of Anionic Poly(N-isopropylacrylamide-co-Acrylic acid) Microgels in the Presence of Cationic Organic Dyes toward Precisely Controlled Uptake/Release of Low-Molecular-Weight Chemical Compound.

    Science.gov (United States)

    Kureha, Takuma; Shibamoto, Takahisa; Matsui, Shusuke; Sato, Takaaki; Suzuki, Daisuke

    2016-05-10

    Changes in a microscopic structure of an anionic poly(N-isopropylacrylamide-co-acrylic acid) microgel were investigated using small- and wide-angle X-ray scattering (SWAXS). The scattering profiles of the microgels were analyzed in a wide scattering vector (q) range of 0.07 ≤ q/nm(-1) ≤ 20. In particular, the microscopic structure of the microgel in the presence of a cationic dye rhodamine 6G (R6G) was characterized in terms of its correlation length (ξ), which represents the length scale of the spatial correlation of the network density fluctuations, and characteristic distance (d*), which originated from the local packing of isopropyl groups of two neighboring chains. In the presence of cationic R6G, ξ exhibited a divergent-like behavior, which was not seen in the absence of R6G, and d* was decreased with decreasing the volume of the microgel upon increasing temperature. At the same time, the amount of R6G adsorbed per unit mass of the microgel increased upon heating. These results suggested that a coil-to-globule transition of the poly(N-isopropylacrylamide) chains in the present anionic microgel occurred because of efficiently screened, thus, short ranged electrostatic repulsion between the charged groups, and hydrophobic interaction between the isopropyl groups in the presence of cationic R6G. The combination of hydrophobic and electrostatic interaction between the cationic dye and the microgel affected the separation and volume transition behavior of the microgel. PMID:27101468

  11. Precision and reproducibility in AMS radiocarbon measurements.

    Energy Technology Data Exchange (ETDEWEB)

    Hotchkis, M.A.; Fink, D.; Hua, Q.; Jacobsen, G.E.; Lawson, E. M.; Smith, A.M.; Tuniz, C. [Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW (Australia)

    1996-12-31

    Accelerator Mass Spectrometry (AMS) is a technique by which rare radioisotopes such as {sup 14}C can be measured at environmental levels with high efficiency. Instead of detecting radioactivity, which is very weak for long-lived environmental radioisotopes, atoms are counted directly. The sample is placed in an ion source, from which a negative ion beam of the atoms of interest is extracted, mass analysed, and injected into a tandem accelerator. After stripping to positive charge states in the accelerator HV terminal, the ions are further accelerated, analysed with magnetic and electrostatic devices and counted in a detector. An isotopic ratio is derived from the number of radioisotope atoms counted in a given time and the beam current of a stable isotope of the same element, measured after the accelerator. For radiocarbon, {sup 14}C/{sup 13}C ratios are usually measured, and the ratio of an unknown sample is compared to that of a standard. The achievable precision for such ratio measurements is limited primarily by {sup 14}C counting statistics and also by a variety of factors related to accelerator and ion source stability. At the ANTARES AMS facility at Lucas Heights Research Laboratories we are currently able to measure {sup 14}C with 0.5% precision. In the two years since becoming operational, more than 1000 {sup 14}C samples have been measured. Recent improvements in precision for {sup 14}C have been achieved with the commissioning of a 59 sample ion source. The measurement system, from sample changing to data acquisition, is under common computer control. These developments have allowed a new regime of automated multi-sample processing which has impacted both on the system throughput and the measurement precision. We have developed data evaluation methods at ANTARES which cross-check the self-consistency of the statistical analysis of our data. Rigorous data evaluation is invaluable in assessing the true reproducibility of the measurement system and aids in

  12. Individual Assessment of Brain Tissue Changes in MS and the Effect of Focal Lesions on Short-Term Focal Atrophy Development in MS: A Voxel-Guided Morphometry Study

    Directory of Open Access Journals (Sweden)

    Jan Fox

    2016-04-01

    Full Text Available We performed voxel-guided morphometry (VGM investigating the mechanisms of brain atrophy in multiple sclerosis (MS related to focal lesions. VGM maps detect regional brain changes when comparing 2 time points on high resolution T1-weighted (T1w magnetic resonace imaging (MRI. Two T1w MR datasets from 92 relapsing-remitting MS patients obtained 12 months apart were analysed with VGM. New lesions and volume changes of focal MS lesions as well as in the surrounding tissue were identified by visual inspection on colour coded VGM maps. Lesions were dichotomized in active and inactive lesions. Active lesions, defined by either new lesions (NL (volume increase > 5% in VGM, chronic enlarging lesions (CEL (pre-existent T1w lesions with volume increase > 5%, or chronic shrinking lesions (CSL (pre-existent T1w lesions with volume reduction > 5% in VGM, were accompanied by tissue shrinkage in surrounding and/or functionally related regions. Volume loss within the corpus callosum was highly correlated with the number of lesions in its close proximity. Volume loss in the lateral geniculate nucleus was correlated with lesions along the optic radiation. VGM analysis provides strong evidence that all active lesion types (NL, CEL, and CSL contribute to brain volume reduction in the vicinity of lesions and/or in anatomically and functionally related areas of the brain.

  13. Individual Assessment of Brain Tissue Changes in MS and the Effect of Focal Lesions on Short-Term Focal Atrophy Development in MS: A Voxel-Guided Morphometry Study

    Science.gov (United States)

    Fox, Jan; Kraemer, Matthias; Schormann, Thorsten; Dabringhaus, Andreas; Hirsch, Jochen; Eisele, Philipp; Szabo, Kristina; Weiss, Christel; Amann, Michael; Weier, Katrin; Naegelin, Yvonne; Kappos, Ludwig; Gass, Achim

    2016-01-01

    We performed voxel-guided morphometry (VGM) investigating the mechanisms of brain atrophy in multiple sclerosis (MS) related to focal lesions. VGM maps detect regional brain changes when comparing 2 time points on high resolution T1-weighted (T1w) magnetic resonace imaging (MRI). Two T1w MR datasets from 92 relapsing-remitting MS patients obtained 12 months apart were analysed with VGM. New lesions and volume changes of focal MS lesions as well as in the surrounding tissue were identified by visual inspection on colour coded VGM maps. Lesions were dichotomized in active and inactive lesions. Active lesions, defined by either new lesions (NL) (volume increase > 5% in VGM), chronic enlarging lesions (CEL) (pre-existent T1w lesions with volume increase > 5%), or chronic shrinking lesions (CSL) (pre-existent T1w lesions with volume reduction > 5%) in VGM, were accompanied by tissue shrinkage in surrounding and/or functionally related regions. Volume loss within the corpus callosum was highly correlated with the number of lesions in its close proximity. Volume loss in the lateral geniculate nucleus was correlated with lesions along the optic radiation. VGM analysis provides strong evidence that all active lesion types (NL, CEL, and CSL) contribute to brain volume reduction in the vicinity of lesions and/or in anatomically and functionally related areas of the brain. PMID:27043553

  14. Manual on brachytherapy. Incorporating: Applications guide, procedures guide, basics guide

    International Nuclear Information System (INIS)

    In addition to a basic guide to the principles of the production of ionizing radiation and to methods of radiation protection and dosimetry, this booklet includes information about radiation protection procedures for brachytherapy

  15. Guide to energy management

    CERN Document Server

    Capehart, B L

    2002-01-01

    This thoroughly revised and updated, Guide to Energy Management, Fourth Edition is a manager's guide to the most important areas of energy cost cutting. Written by three of the most respected energy professionals in the industry, the book provides valuabl

  16. Vegan Food Guide

    Science.gov (United States)

    ... Story" 5 Things to Know About Zika & Pregnancy Vegan Food Guide KidsHealth > For Parents > Vegan Food Guide ... a Vegan Diet Is Vegetarian the Same as Vegan? Lots of people limit their intake of meat — ...

  17. Electromagnetic ultrasonic guided waves

    CERN Document Server

    Huang, Songling; Li, Weibin; Wang, Qing

    2016-01-01

    This book introduces the fundamental theory of electromagnetic ultrasonic guided waves, together with its applications. It includes the dispersion characteristics and matching theory of guided waves; the mechanism of production and theoretical model of electromagnetic ultrasonic guided waves; the effect mechanism between guided waves and defects; the simulation method for the entire process of electromagnetic ultrasonic guided wave propagation; electromagnetic ultrasonic thickness measurement; pipeline axial guided wave defect detection; and electromagnetic ultrasonic guided wave detection of gas pipeline cracks. This theory and findings on applications draw on the author’s intensive research over the past eight years. The book can be used for nondestructive testing technology and as an engineering reference work. The specific implementation of the electromagnetic ultrasonic guided wave system presented here will also be of value for other nondestructive test developers.

  18. Feasibility Study of a Hand Guided Robotic Drill for Cochleostomy

    OpenAIRE

    2014-01-01

    The concept of a hand guided robotic drill has been inspired by an automated, arm supported robotic drill recently applied in clinical practice to produce cochleostomies without penetrating the endosteum ready for inserting cochlear electrodes. The smart tactile sensing scheme within the drill enables precise control of the state of interaction between tissues and tools in real-time. This paper reports development studies of the hand guided robotic drill where the same consistent outcomes, au...

  19. Precise time frequency synchronization technology for bistatic radar

    Institute of Scientific and Technical Information of China (English)

    Huang Yulin; Yang Jianyu; Wu Junjie; Xiong Jintao

    2008-01-01

    A complete method of synchronization technology of bistatic radar using global position system (GPS) is presented.The pulse per second signal (1PPS) is elaborately modified to increase the time synchronization precision and keep loop locking.A very high time synchronization precision is achieved.Using the modified 1PPS to discipline the local OCXO,the reference frequency signal achieves both high long term stability (LTS) and short term stability (STS) properties.An algorithm,named phase abrupt change CFAR is presented to restrain the 1PPS phase abrupt change and keep loop locking.The experimental results indicate that this time and frequency synchronization method is effective and the time synchronization precision of the synchronization system can be improved from ±100 ns to ±25 ns.In addition,the phase noise is improved to 20 dB.

  20. Finishing of precision generated metal optical components

    International Nuclear Information System (INIS)

    Diamond turning and precision generation of aspheric metal surfaces has promoted a change in lapping techniques due to the extremely close figure tolerances and surface finishes that have been achieved. Special tooling, diamond abrasive, silicon oil and special techniques used to polish the unusual aspheric figures are described. The studies include small flat diamond turned samples of copper, electroplated copper, electroplated silver, electroplated nickel and silver as well as large aspheres such as an f/0.75, 35 cm dia copper ellipse. Results from cleaning studies on flat samples using ultrasonics and vapor degreasers are also summarized. Interferograms of wavefront distortion and analysis of focal volume are included as well as 10.6 μm reflectivity and a summary of laser damage experiments. (TFD)

  1. Pulsating White Dwarf Stars and Precision Asteroseismology

    CERN Document Server

    Winget, D E

    2008-01-01

    Galactic history is written in the white dwarf stars. Their surface properties hint at interiors composed of matter under extreme conditions. In the forty years since their discovery, pulsating white dwarf stars have moved from side-show curiosities to center stage as important tools for unraveling the deep mysteries of the Universe. Innovative observational techniques and theoretical modeling tools have breathed life into precision asteroseismology. We are just learning to use this powerful tool, confronting theoretical models with observed frequencies and their time rate-of-change. With this tool, we calibrate white dwarf cosmochronology; we explore equations of state; we measure stellar masses, rotation rates, and nuclear reaction rates; we explore the physics of interior crystallization; we study the structure of the progenitors of Type Ia supernovae, and we test models of dark matter. The white dwarf pulsations are at once the heartbeat of galactic history and a window into unexplored and exotic physics.

  2. Highly damped kinematic coupling for precision instruments

    Energy Technology Data Exchange (ETDEWEB)

    Hale, Layton C. (Livermore, CA); Jensen, Steven A. (Livermore, CA)

    2001-01-01

    A highly damped kinematic coupling for precision instruments. The kinematic coupling provides support while causing essentially no influence to its nature shape, with such influences coming, for example, from manufacturing tolerances, temperature changes, or ground motion. The coupling uses three ball-cone constraints, each combined with a released flexural degree of freedom. This arrangement enables a gain of higher load capacity and stiffness, but can also significantly reduce the friction level in proportion to the ball radius divided by the distance between the ball and the hinge axis. The blade flexures reduces somewhat the stiffness of the coupling and provides an ideal location to apply constrained-layer damping which is accomplished by attaching a viscoelastic layer and a constraining layer on opposite sides of each of the blade flexures. The three identical ball-cone flexures provide a damped coupling mechanism to kinematically support the projection optics system of the extreme ultraviolet lithography (EUVL) system, or other load-sensitive apparatus.

  3. Role of telecommunications in precision agriculture

    Science.gov (United States)

    Precision agriculture has been made possible by the confluence of several technologies: geographic positioning systems, geographic information systems, image analysis software, low-cost microcomputer-based variable rate controller/recorders, and precision tractor guidance systems. While these techn...

  4. Using hyperspectral data in precision farming applications

    Science.gov (United States)

    Precision farming practices such as variable rate applications of fertilizer and agricultural chemicals require accurate field variability mapping. This chapter investigated the value of hyperspectral remote sensing in providing useful information for five applications of precision farming: (a) Soil...

  5. Precision Electrospray Thruster Assembly (PETA) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — New low cost, low volume, low power, rugged electrospray thrusters will be ideal as actuators for precision thrusting, if provided with precision high voltage power...

  6. Managerial Accounting. Study Guide.

    Science.gov (United States)

    Plachta, Leonard E.

    This self-instructional study guide is part of the materials for a college-level programmed course in managerial accounting. The study guide is intended for use by students in conjuction with a separate textbook, Horngren's "Accounting for Management Control: An Introduction," and a workbook, Curry's "Student Guide to Accounting for Management…

  7. Precision QCD measurements at HERA

    Directory of Open Access Journals (Sweden)

    Pirumov Hayk

    2014-01-01

    Full Text Available A review of recent experimental results on perturbative QCD from the HERA experiments H1 and ZEUS is presented. All inclusive deep inelastic cross sections measured by the H1 and ZEUS collaborations in neutral and charged current unpolarised ep scattering are combined. They span six orders of magnitude in negative four-momentum-transfer squared, Q2, and in Bjorken x. This data set is used as the sole input to NLO and NNLO QCD analyses to determine new sets of parton distributions, HERAPDF2.0, with small experimental uncertainties and an estimate of model and parametrisation uncertainties. Also shown are new results on inclusive jet, dijet and trijet differential cross sections measured in neutral current deep inelastic scattering. The precision jet data is used to extract the strong coupling αs at NLO with small experimental errors.

  8. Precision moisture generation and measurement.

    Energy Technology Data Exchange (ETDEWEB)

    Thornberg, Steven Michael; White, Michael I.; Irwin, Adriane Nadine

    2010-03-01

    In many industrial processes, gaseous moisture is undesirable as it can lead to metal corrosion, polymer degradation, and other materials aging processes. However, generating and measuring precise moisture concentrations is challenging due to the need to cover a broad concentration range (parts-per-billion to percent) and the affinity of moisture to a wide range surfaces and materials. This document will discuss the techniques employed by the Mass Spectrometry Laboratory of the Materials Reliability Department at Sandia National Laboratories to generate and measure known gaseous moisture concentrations. This document highlights the use of a chilled mirror and primary standard humidity generator for the characterization of aluminum oxide moisture sensors. The data presented shows an excellent correlation in frost point measured between the two instruments, and thus provides an accurate and reliable platform for characterizing moisture sensors and performing other moisture related experiments.

  9. Precision cosmology and the landscape

    Energy Technology Data Exchange (ETDEWEB)

    Bousso, Raphael; Bousso, Raphael

    2006-10-01

    After reviewing the cosmological constant problem -- why is Lambda not huge? -- I outline the two basic approaches that had emerged by the late 1980s, and note that each made a clear prediction. Precision cosmological experiments now indicate that the cosmological constant is nonzero. This result strongly favors the environmental approach, in which vacuum energy can vary discretely among widely separated regions in the universe. The need to explain this variation from first principles constitutes an observational constraint on fundamental theory. I review arguments that string theory satisfies this constraint, as it contains a dense discretuum of metastable vacua. The enormous landscape of vacua calls for novel, statistical methods of deriving predictions, and it prompts us to reexamine our description of spacetime on the largest scales. I discuss the effects of cosmological dynamics, and I speculate that weighting vacua by their entropy production may allow for prior-free predictions that do not resort to explicitly anthropic arguments.

  10. Precise Nanoelectronics with Adatom Chains

    Science.gov (United States)

    Yamada, Toshishige

    1999-01-01

    Adatom chains on an atomically regulated substrate will be building components in future precise nanoelectronics. Adatoms need to be secured with chemical bonding, but then electronic isolation between the adatom and substrate systems is not guaranteed. A one-dimensional model shows that good isolation with existence of surface states is expected on an s-p crossing substrate such as Si, Ge, or GaAs, reflecting the bulk nature of the substrate. Isolation is better if adatoms are electronically similar to the substrate atoms, and can be manipulated by hydrogenation. Chain structures with group IV adatoms with two chemical bonds, or group III adatoms with one chemical bond, are semiconducting, reflecting the surface nature of the substrate. These structures are unintentionally doped due to the charge transfer across the chemical bonds. Physical properties of adatom chains have to be determined for the unified adatom-substrate system.

  11. Precision cosmology and the landscape

    International Nuclear Information System (INIS)

    After reviewing the cosmological constant problem--why is Lambda not huge?--I outline the two basic approaches that had emerged by the late 1980s, and note that each made a clear prediction. Precision cosmological experiments now indicate that the cosmological constant is nonzero. This result strongly favors the environmental approach, in which vacuum energy can vary discretely among widely separated regions in the universe. The need to explain this variation from first principles constitutes an observational constraint on fundamental theory. I review arguments that string theory satisfies this constraint, as it contains a dense discretuum of metastable vacua. The enormous landscape of vacua calls for novel, statistical methods of deriving predictions, and it prompts us to reexamine our description of spacetime on the largest scales. I discuss the effects of cosmological dynamics, and I speculate that weighting vacua by their entropy production may allow for prior-free predictions that do not resort to explicitly anthropic arguments

  12. Precision Spectroscopy of Atomic Hydrogen

    Science.gov (United States)

    Beyer, A.; Parthey, Ch G.; Kolachevsky, N.; Alnis, J.; Khabarova, K.; Pohl, R.; Peters, E.; Yost, D. C.; Matveev, A.; Predehl, K.; Droste, S.; Wilken, T.; Holzwarth, R.; Hänsch, T. W.; Abgrall, M.; Rovera, D.; Salomon, Ch; Laurent, Ph; Udem, Th

    2013-12-01

    Precise determinations of transition frequencies of simple atomic systems are required for a number of fundamental applications such as tests of quantum electrodynamics (QED), the determination of fundamental constants and nuclear charge radii. The sharpest transition in atomic hydrogen occurs between the metastable 2S state and the 1S ground state. Its transition frequency has now been measured with almost 15 digits accuracy using an optical frequency comb and a cesium atomic clock as a reference [1]. A recent measurement of the 2S - 2P3/2 transition frequency in muonic hydrogen is in significant contradiction to the hydrogen data if QED calculations are assumed to be correct [2, 3]. We hope to contribute to this so-called "proton size puzzle" by providing additional experimental input from hydrogen spectroscopy.

  13. Precision experiments with exotic nuclei

    International Nuclear Information System (INIS)

    Progress and modern developments of secondary nuclear beam facilities based on the in-flight and ISOL separation methods are outlined. Precision experiments with nuclear beams characterized by large emittances have been performed by using special ion-optical conditions in spectrometers. A new generation of experiments have been started with stored and cooled exotic nuclei at sub-eV and at relativistic energies using the combination of an ISOL facility and an ion trap or the combination of an in-flight system with a storage and cooler ring, respectively. Both experimental scenarios are realized by ISOLDE and the ISOLTRAP at CERN and the fragment separator FRS in combination with the experimental storage ring ESR at GSI. The power and the potential of these devices are illustrated by direct mass and lifetime measurements. (orig.)

  14. INFORMATION AND THE ADOPTION OF PRECISION FARMING

    OpenAIRE

    Daberkow, Stan G.; McBride, William D.

    2001-01-01

    This study examines the relationship between precision farming information sources and precision farming adoption. The analysis accounts for the fact that not all farmers are aware of precision farming techniques and that those who are aware may not be a random sample. Results indicate that many information sources increase adoption relative to information only from the media, but contact with crop consultants has had the greatest impact on the adoption of precision farming technologies.

  15. The efficacy of Elekta Synergy image-guided radiotherapy

    International Nuclear Information System (INIS)

    We evaluated the efficacy of Elekta Synergy image-guided radiotherapy (IGRT) system equipped with cone beam CT (CBCT) for high accuracy radiation therapy. In cases set up with body marking who had large set up error could be adjusted by this system within 1 mm error. IGRT with CBCT correction provided precise set up. Elekta Synergy IGRT system is useful for high accuracy set up and will facilitate novel precise radiotherapy techniques. (author)

  16. Ultrasound-Guided Breast Biopsy

    Science.gov (United States)

    ... Professions Site Index A-Z Ultrasound-Guided Breast Biopsy An ultrasound-guided breast biopsy uses sound waves ... Guided Breast Biopsy? What is Ultrasound-Guided Breast Biopsy? Lumps or abnormalities in the breast are often ...

  17. Next generation sequencing in cancer: opportunities and challenges for precision cancer medicine.

    Science.gov (United States)

    Paolillo, Carmela; Londin, Eric; Fortina, Paolo

    2016-01-01

    Over the past decade, testing the genes of patients and their specific cancer types has become standardized practice in medical oncology since somatic mutations, changes in gene expression and epigenetic modifications are all hallmarks of cancer. However, while cancer genetic assessment has been limited to single biomarkers to guide the use of therapies, improvements in nucleic acid sequencing technologies and implementation of different genome analysis tools have enabled clinicians to detect these genomic alterations and identify functional and disease-associated genomic variants. Next-generation sequencing (NGS) technologies have provided clues about therapeutic targets and genomic markers for novel clinical applications when standard therapy has failed. While Sanger sequencing, an accurate and sensitive approach, allows for the identification of potential novel variants, it is however limited by the single amplicon being interrogated. Similarly, quantitative and qualitative profiling of gene expression changes also represents a challenge for the cancer field. Both RT-PCR and microarrays are efficient approaches, but are limited to the genes present on the array or being assayed. This leaves vast swaths of the transcriptome, including non-coding RNAs and other features, unexplored. With the advent of the ability to collect and analyze genomic sequence data in a timely fashion and at an ever-decreasing cost, many of these limitations have been overcome and are being incorporated into cancer research and diagnostics giving patients and clinicians new hope for targeted and personalized treatment. Below we highlight the various applications of next-generation sequencing in precision cancer medicine. PMID:27542004

  18. Precision grinding process development for brittle materials

    International Nuclear Information System (INIS)

    High performance, brittle materials are the materials of choice for many of today's engineering applications. This paper describes three separate precision grinding processes developed at Lawrence Liver-more National Laboratory to machine precision ceramic components. Included in the discussion of the precision processes is a variety of grinding wheel dressing, truing and profiling techniques

  19. Product Approximation of Grade and Precision

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xian-yong; MO Zhi-wen

    2005-01-01

    The normal graded approximation and variable precision approximation are defined in approximate space. The relationship between graded approximation and variable precision approximation is studied, and an important formula of conversion between them is achieved. The product approximation of gradeand precision is defined and its basic properties are studied.

  20. Precision Farming and Conservation Advances Agricultural Sustainability

    Science.gov (United States)

    To many, Precision Farming, more formally termed Precision Agriculture, seems like an oxymoron. Yet site-specific management makes sense to an exponentially growing number of farmers. So where is Precision Farming headed? The short answer is that it is being extended from a focus on crop productio...

  1. Lattice Structure of Variable Precision Rough Sets

    OpenAIRE

    Basu, Sumita

    2016-01-01

    The main purpose of this paper is to study the lattice structure of variable precision rough sets. The notion of variation in precision of rough sets have been further extended to variable precision rough set with variable classification error and its algebraic properties are also studied.

  2. CT-guided ozone/steroid therapy for the treatment of degenerative spinal disease - effect of age, gender, disc pathology and multi-segmental changes

    Energy Technology Data Exchange (ETDEWEB)

    Oder, Bernhard; Loewe, Maria; Reisegger, Michael; Thurnher, Siegfried A. [Hospital Brothers of St. John of God, Department of Radiology and Nuclear Medicine, Vienna (Austria); Lang, Wilfried [Hospital Brothers of St. John of God, Department of Neurology, Vienna (Austria); Ilias, Wilfried [Hospital Brothers of St. John of God, Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, Vienna (Austria)

    2008-09-15

    Oxygen-ozone nucleolysis (ONL) is a new, minimally invasive procedure for the treatment of discogenic low back pain with or without radicular symptoms. The aim of the present study was to determine associations between the morphology of the basic disease, patient-specific factors and the outcome of the treatment. Six hundred and twelve patients not responding to conservative therapy were divided into five groups (disc bulging, disc herniation, postoperative patients, osteochondrosis, others) and subjected to nucleolysis with ozone and to periradicular infiltration with steroids and local anaesthesia. The success of treatment was assessed by means of a visual analog pain scale (VAS) and the Oswestry Disability Index (ODI). A significant reduction in the VAS was registered after 2 and 6 months (from 8.6 to 5.4 and 6.0; p<0.001) in all patient groups; an excellent therapy response (VAS below 3.0) was achieved by about a third of the patients. A significant improvement in ODI was registered in all patients (46 to 31; p<0.001), most pronounced in the herniation group (25.5, p=0.015). Patients below 50 years had significantly better values in the VAS and ODI score 6 months after treatment. Final VAS and ODI scores for patients with a single diseased segment were 4.2 and 28.0, in two affected segments 6.5 and 32 and in three segments 6.7 and 38.5 (p<0.001 and p=0.051). ONL with periradicular steroid therapy might exert a functional and sustained analgesic effect in patients with degenerative changes in the lumbar spine not responding to conservative therapy and was most effective below 50 years with disc herniation in one segment. (orig.)

  3. Use of positron emission tomography scan response to guide treatment change for locally advanced gastric cancer: the Memorial Sloan Kettering Cancer Center experience

    Science.gov (United States)

    Won, Elizabeth; Shah, Manish A.; Schöder, Heiko; Strong, Vivian E.; Coit, Daniel G.; Brennan, Murray F.; Kelsen, David P.; Janjigian, Yelena Y.; Tang, Laura H.; Capanu, Marinela; Rizk, Nabil P.; Allen, Peter J.; Bains, Manjit S.

    2016-01-01

    Background Early metabolic response on 18-fluorodeoxyglucose-positron emission tomography (FDG-PET) during neoadjuvant chemotherapy is PET non-responders have poor outcomes whether continuing chemotherapy or proceeding directly to surgery. Use of PET may identify early treatment failure, sparing patients from inactive therapy and allowing for crossover to alternative therapies. We examined the effectiveness of PET directed switching to salvage chemotherapy in the PET non-responders. Methods Patients with locally advanced resectable FDG-avid gastric or gastroesophageal junction (GEJ) adenocarcinoma received bevacizumab 15 mg/kg, epirubicin 50 mg/m2, cisplatin 60 mg/m2 day 1, and capecitabine 625 mg/m2 bid (ECX) every 21 days. PET scan was obtained at baseline and after cycle 1. PET responders, (i.e., ≥35% reduction in FDG uptake at the primary tumor) continued ECX + bev. Non-responders switched to docetaxel 30 mg/m2, irinotecan 50 mg/mg2 day 1 and 8 plus bevacizumab every 21 days for 2 cycles. Patients then underwent surgery. The primary objective was to improve the 2-year disease free survival (DFS) from 30% (historical control) to 53% in the non-responders. Results Twenty evaluable patients enrolled before the study closed for poor accrual. Eleven were PET responders and the 9 non-responders switched to the salvage regimen. With a median follow-up of 38.2 months, the 2-year DFS was 55% [95% confidence interval (CI), 30–85%] in responders compared with 56% in the non-responder group (95% CI, 20–80%, P=0.93). Conclusions The results suggest that changing chemotherapy regimens in PET non-responding patients may improve outcomes. Results from this pilot trial are hypothesis generating and suggest that PET directed neoadjuvant therapy merits evaluation in a larger trial.

  4. CT-guided ozone/steroid therapy for the treatment of degenerative spinal disease - effect of age, gender, disc pathology and multi-segmental changes

    International Nuclear Information System (INIS)

    Oxygen-ozone nucleolysis (ONL) is a new, minimally invasive procedure for the treatment of discogenic low back pain with or without radicular symptoms. The aim of the present study was to determine associations between the morphology of the basic disease, patient-specific factors and the outcome of the treatment. Six hundred and twelve patients not responding to conservative therapy were divided into five groups (disc bulging, disc herniation, postoperative patients, osteochondrosis, others) and subjected to nucleolysis with ozone and to periradicular infiltration with steroids and local anaesthesia. The success of treatment was assessed by means of a visual analog pain scale (VAS) and the Oswestry Disability Index (ODI). A significant reduction in the VAS was registered after 2 and 6 months (from 8.6 to 5.4 and 6.0; p<0.001) in all patient groups; an excellent therapy response (VAS below 3.0) was achieved by about a third of the patients. A significant improvement in ODI was registered in all patients (46 to 31; p<0.001), most pronounced in the herniation group (25.5, p=0.015). Patients below 50 years had significantly better values in the VAS and ODI score 6 months after treatment. Final VAS and ODI scores for patients with a single diseased segment were 4.2 and 28.0, in two affected segments 6.5 and 32 and in three segments 6.7 and 38.5 (p<0.001 and p=0.051). ONL with periradicular steroid therapy might exert a functional and sustained analgesic effect in patients with degenerative changes in the lumbar spine not responding to conservative therapy and was most effective below 50 years with disc herniation in one segment. (orig.)

  5. Embracing change.

    Science.gov (United States)

    Orr, Patty; Davenport, Doris

    2015-03-01

    This article challenges the way nurses have thought about the business of nursing practice and education, while exposing emerging innovations that are calling nurses to action. Several quality measurement programs and the Affordable Care Act are discussed in relation to changes in nursing practice that will be required to meet the challenges of an evolving health care system. Using a change theory as the framework to guide both transformational and incremental planned change will increase the chance of success. Selected change theories are considered and one theory is used to illustrate usefulness in facilitating change in nursing practice. PMID:25680483

  6. Farmers’ Perception of Precision Farming Technology among Hungarian Farmers

    Directory of Open Access Journals (Sweden)

    Enikő Lencsés

    2014-11-01

    Full Text Available Many technologies have appeared in agriculture to reduce the harmful effects of chemical use. One of these technologies is precision farming technology. Precision farming technology should not be considered as only the latest plant production technology or only a new agro-management tool. It is achieved only when the results of electronics and IT equipment are realized in the variable rate treatments zone-by-zone. The advantages and disadvantages of this technology highly depend on the heterogeneity of soil, the knowledge and attitude of the manager and the staff. This is the reason why opinions about the technology effects are so wide. This paper shows the results of the investigation based on interviews about the adoption and knowledge of precision farming technology among Hungarian crop producers. This technology is mostly used by farms over 300 hectares with young farmers. The most characteristic elements were precision fertilization and tractor guidance. The survey examined three groups of farmers with respect to whether they apply precision farming elements or not. We refer to them as “users”, “planners” and “non-users”. According to the survey, the opinions of the “user” and the “non-user” groups of farmers are not significantly different regarding the impacts of precision farming technology (the main advantages were the change in yield quantity, chemical usage and income. Furthermore, the opinions of the farmers regarding the changes in variable costs resulting from the adoption of precision farming technology were also examined (measured in percent. Box-plot analysis was used for this examination. According to the opinion of the “user” group of farmers, the highest cost savings occurred in fertilizer and herbicide costs.

  7. Precise modelling of HSC machine tool thermal behaviour

    Directory of Open Access Journals (Sweden)

    J. Jędrzejewski

    2007-09-01

    Full Text Available Purpose: The development of precision machine tools requires modelling, simulation and optimization, especially the accurate modelling of machine tool thermal behaviour aimed at improving the machine tool design.Design/methodology/approach: This paper discusses machine tool design improvement based on thermal behaviour modelling and the complexities involved. A highly accurate thermal model of the HSC machine tool is presented and the necessity of including the whole complex of factors affecting machine tool behaviour and error compensation is highlighted. Modelling problems are illustrated with examples of accurate modelling and simulation of machine tool behaviour, aimed at minimizing thermal disturbances in machining precision.Findings: The precise modelling of HSC machine tools dynamic spindle displacement during a change of rotational speed.Research limitations/implications: The transitional states of spindle speed changes are very complex and difficult to precise recognition.Practical implications: The need of integrated complex modelling of precise HSC machine tools thermal behaviour.Originality/value: All models used for machine tool behaviour simulation are fully original.

  8. Addressing Climate Change Adaptation in Regional Transportation Plans in California: A Guide and Online Visualization Tool for Planners to Incorporate Risks of Climate Change Impacts in Policy and Decision-Making

    Science.gov (United States)

    Tao, W.; Tucker, K.; DeFlorio, J.

    2012-12-01

    The reality of a changing climate means that transportation and planning agencies need to understand the potential effects of changes in storm activity, sea levels, temperature, and precipitation patterns; and develop strategies to ensure the continuing robustness and resilience of transportation infrastructure and services. This is a relatively new challenge for California's regional planning agencies - adding yet one more consideration to an already complex and multifaceted planning process. In that light, the California Department of Transportation (Caltrans) is developing a strategy framework using a module-based process that planning agencies can undertake to incorporating the risks of climate change impacts into their decision-making and long-range transportation plans. The module-based approach was developed using a best practices survey of existing work nationally, along with a set of structured interviews with metropolitan planning organizations (MPOs) and regional transportation planning agencies (RTPAs) within California. Findings led to the development of a process, as well as a package of foundational geospatial layers (i.e. the Statewide Transportation Asset Geodatabase - STAG), primarily comprising state and Federal transportation assets. These assets are intersected with a set of geospatial layers for the climate stressors of relevance in the state which are placed in the same reference layers as the STAG; thus providing a full set of GIS layers that can be a starting point for MPOs/RTPAs that want to follow the step-by-step module-based approach in its entirety. The fast-paced changes in science and climate change knowledge requires a flexible platform to display continuously evolving information. To this end, the development of the modules are accompanied by a set of geospatial analysis disseminated using an online web portal. In this way, the information can be relayed to MPO/RTPAs in a easy-to-use fashion that can help them follow the modules

  9. Precision radiocarbon dating of a Late Holocene vegetation history

    International Nuclear Information System (INIS)

    The purpose of this research is to precisely date vegetation changes associated with early human presence in the Hawkes Bay region. A sequence of AMS radiocarbon ages was obtained using a new technique developed at Rafter Radiocarbon Laboratory. A density separation method was used to concentrate pollen and spores extracted from unconsolidated lake sediments from a small-enclosed lake in coastal foothills of southern Hawkes Bay. Radiocarbon measurements were made on fractions of concentrated pollen, separated from associated organic debris. These ages directly date vegetation communities used to reconstruct the vegetation history of the region. This technique results in more accurate dating of Late Holocene vegetation changes interpreted from palynological analyses than techniques formerly used. Precision dating of palynological studies of New Zealand prehistory and history is necessary for correlation of vegetation changes to cultural changes because of the short time span of human occupation of New Zealand. (author). 35 refs., 3 figs., 1 tab

  10. SharePoint User's Guide

    CERN Document Server

    Corporation, Infusion Development

    2009-01-01

    This straightforward guide shows SharePoint users how to create and use web sites for sharing and collaboration. Learn to use the document and picture libraries for adding and editing content, add discussion boards and surveys, receive alerts when documents and information have been added or changed, and enhance security. Designed to help you find answers quickly, the book shows how to make the most of SharePoint for productivity and collaboration.

  11. DRAFT CAREER PATH - DESCRIPTIONS AND EVALUATION GUIDE

    CERN Multimedia

    1999-01-01

    As indicated in the summary of the Standing Concertation Committee meeting of 3 March 1999, the Committee has approved the above draft guide concerning Career Paths II to VII on a test basis for at least one year.During this period, Personnel Division has been asked to monitor the applicability of this guide for possible future implementation (establishment of vacancies for recruitment, change of career path evaluations, salary survey comparisons) and to report back to the Standing Concertation Committee after approximately one year.Copies of the draft guide are available on request in divisional secretariats.Personnel DivisionTel.74480

  12. GreyGuide Forum and Repository

    OpenAIRE

    Biagioni, Stefania; Farace, Dominic

    2014-01-01

    We present the GreyGuide: an online forum and repository of good practice in the field of grey literature. The launch of the GreyGuide Repository took place in December 2013 at the Fifteenth International Conference on Grey Literature. Since then, the acquisition of both proposed and published good practices are underway. The GreyGuide as an online forum is currently in a developmental stage and is influenced by the changes that have taken place in GreyNet's new infrastructure commencing in J...

  13. Short RNA guides cleavage by eukaryotic RNase III.

    Directory of Open Access Journals (Sweden)

    Bruno Lamontagne

    Full Text Available In eukaryotes, short RNAs guide a variety of enzymatic activities that range from RNA editing to translation repression. It is hypothesized that pre-existing proteins evolved to bind and use guide RNA during evolution. However, the capacity of modern proteins to adopt new RNA guides has never been demonstrated. Here we show that Rnt1p, the yeast orthologue of the bacterial dsRNA-specific RNase III, can bind short RNA transcripts and use them as guides for sequence-specific cleavage. Target cleavage occurred at a constant distance from the Rnt1p binding site, leaving the guide RNA intact for subsequent cleavage. Our results indicate that RNase III may trigger sequence-specific RNA degradation independent of the RNAi machinery, and they open the road for a new generation of precise RNA silencing tools that do not trigger a dsRNA-mediated immune response.

  14. High precision redundant robotic manipulator

    International Nuclear Information System (INIS)

    A high precision redundant robotic manipulator for overcoming contents imposed by obstacles or imposed by a highly congested work space is disclosed. One embodiment of the manipulator has four degrees of freedom and another embodiment has seven degrees of freedom. Each of the embodiments utilize a first selective compliant assembly robot arm (SCARA) configuration to provide high stiffness in the vertical plane, a second SCARA configuration to provide high stiffness in the horizontal plane. The seven degree of freedom embodiment also utilizes kinematic redundancy to provide the capability of avoiding obstacles that lie between the base of the manipulator and the end effector or link of the manipulator. These additional three degrees of freedom are added at the wrist link of the manipulator to provide pitch, yaw and roll. The seven degrees of freedom embodiment uses one revolute point per degree of freedom. For each of the revolute joints, a harmonic gear coupled to an electric motor is introduced, and together with properly designed based servo controllers provide an end point repeatability of less than 10 microns. 3 figs

  15. Precise location of nonmetallic pipelines

    International Nuclear Information System (INIS)

    A method is described to conduct precise surveys of nonmetallic pipelines. After a thin stranded wire is pulled through a part of the pipe first an inductive or capacitative prelocation is made, in which especially curves are marked. After that with this wire a go-devil with a 500 mCi 60Co-radiation source is moved slowly from reference point to reference point. On the ground plane the corresponding maximum of the radiation intensity is detected and marked as the position of the pipe. About the experiences of the location of two local gas pipelines with 4987 and 11897 km length is reported. The average length of the located sections was about 300 m, the average distance between two reference points was a little more than 8 m. In the case of curves the distances were reduced to 0.5 - 1.0 m. The output of location was 16 h/km, the daily output ca. 600 m. The accuracy is better than +- 10 cm, while in the case of the inductive prelocation deviations of more than 50 cm could be found. During the locations the delivery of gas was uninterrupted. It can be carried out also in thickly populated regions without any danger by radioactive radiation. (Author)

  16. Implications of precision electroweak data

    CERN Document Server

    Hagiwara, K

    1996-01-01

    There are two aspects to the 1995 summer update of the combined preliminary electroweak data from LEP and SLC. On the one hand, agreement between experiments and the Standard Model (SM) has improved for the line-shape and the asymmetry data. The \\tau widths and asymmetries are now consistent with e--\\mu--\\tau universality, and all the asymmetry data including the left-right asymmetry from SLC are consistent with the SM (16\\%CL). On the other hand, a discrepancy between experiments and SM predictions is sharpened for two observables, R_b and R_c, where R_q is the partial Z boson width ratio \\Gamma_q/\\Gamma_h. R_b is 3\\% larger (3.7\\sigma) and R_c is 11\\% smaller (2.5\\sigma) than the SM predictions. When combined the SM is ruled out at the 99.99\\%CL for m_t>170GeV. It is difficult to interpret the 11\\pm 4\\% deficit of R_c, since if we allow only \\Gamma_b and \\Gamma_c to deviate from the SM then the precisely measured ratio R_h=\\Gamma_h/\\Gamma_\\ell forces the QCD coupling to be \\alpha_s\\equiv \\alpha_s(m_Z)_{\\ove...

  17. The Age of Precision Cosmology

    Science.gov (United States)

    Chuss, David T.

    2012-01-01

    In the past two decades, our understanding of the evolution and fate of the universe has increased dramatically. This "Age of Precision Cosmology" has been ushered in by measurements that have both elucidated the details of the Big Bang cosmology and set the direction for future lines of inquiry. Our universe appears to consist of 5% baryonic matter; 23% of the universe's energy content is dark matter which is responsible for the observed structure in the universe; and 72% of the energy density is so-called "dark energy" that is currently accelerating the expansion of the universe. In addition, our universe has been measured to be geometrically flat to 1 %. These observations and related details of the Big Bang paradigm have hinted that the universe underwent an epoch of accelerated expansion known as Uinflation" early in its history. In this talk, I will review the highlights of modern cosmology, focusing on the contributions made by measurements of the cosmic microwave background, the faint afterglow of the Big Bang. I will also describe new instruments designed to measure the polarization of the cosmic microwave background in order to search for evidence of cosmic inflation.

  18. Studying antimatter with laser precision

    CERN Multimedia

    Katarina Anthony

    2012-01-01

    The next generation of antihydrogen trapping devices, ALPHA-2, is moving into CERN’s Antiproton Decelerator (AD) hall. This brand-new experiment will allow the ALPHA collaboration to conduct studies of antimatter with greater precision. ALPHA spokesperson Jeffrey Hangst was recently awarded a grant by the Carlsberg Foundation, which will be used to purchase equipment for the new experiment.   A 3-D view of the new magnet (in blue) and cryostat. The red lines show the paths of laser beams. LHC-type current leads for the superconducting magnets are visible on the top-right of the image. The ALPHA collaboration has been working to trap and study antihydrogen since 2006. Using antiprotons provided by CERN’s Antiproton Decelerator (AD), ALPHA was the first experiment to trap antihydrogen and to hold it long enough to study its properties. “The new ALPHA-2 experiment will use integrated lasers to probe the trapped antihydrogen,” explains Jeffrey Hangst, ALP...

  19. Higgs Precision (Higgcision) Era begins

    CERN Document Server

    Cheung, Kingman; Tseng, Po-Yan

    2013-01-01

    After the discovery of the Higgs boson at the LHC, it is natural to start the research program on the precision study of the Higgs-boson couplings to various standard model (SM) particles. We provide a generic framework for the deviations of the couplings from their SM values by introducing a number of parameters. We show that a large number of models beyond the SM can be covered, including two-Higgs-doublet models, supersymmetric models, little-Higgs models, extended Higgs sectors with singlets, and fourth generation models. We perform global fits to the most updated data from CMS, ATLAS, and Tevatron under various initial conditions of the parameter set. Highlights of the results include: (i) the nonstandard decay branching ratio of the Higgs boson is less than 25%; (ii) the most efficient way to achieve the best fit is to introduce additional particle contributions to the triangular-loop functions of H-gamma-gamma and Hgg vertices; (iii) the 1 sigma allowed range of the relative coupling of HVV is 0.96 +0....

  20. Precision is in their nature

    CERN Multimedia

    Antonella Del Rosso

    2014-01-01

    There are more than 100 of them in the LHC ring and they have a total of about 400 degrees of freedom. Each one has 4 motors and the newest ones have their own beam-monitoring pickups. Their jaws constrain the relativistic, high-energy particles to a very small transverse area and protect the machine aperture. We are speaking about the LHC collimators, those ultra-precise instruments that leave escaping unstable particles no chance.   The internal structure of a new LHC collimator featuring (see red arrow) one of the beam position monitor's pickups. Designed at CERN but mostly produced by very specialised manufacturers in Europe, the LHC collimators are among the most complex elements of the accelerator. Their job is to control and safely dispose of the halo particles that are produced by unavoidable beam losses from the circulating beam core. “The LHC collimation system has been designed to ensure that beam losses in superconducting magnets remain below quench limits in al...

  1. Accuracy and precision in the calculation of phenology metrics

    DEFF Research Database (Denmark)

    Ferreira, Ana Sofia; Visser, Andre; MacKenzie, Brian; Payne, Mark

    2014-01-01

    Phytoplankton phenology (the timing of seasonal events) is a commonly used indicator for evaluating responses of marine ecosystems to climate change. However, phenological metrics are vulnerable to observation-(bloom amplitude, missing data, and observational noise) and analysis-related (temporal...... phenology metric is first determined from a noise- and gap-free time series, and again once it has been modified. We show that precision is a greater concern than accuracy for many of these metrics, an important point that has been hereto overlooked in the literature. The variability in precision between...

  2. Precise fabrication of X-band accelerating structure

    International Nuclear Information System (INIS)

    An accelerating structure with a/λ=0.16 is being fabricated to study a precise fabrication method. A frequency control of each cell better than 10-4 level is required to realize a detuned structure. The present machining level is nearly 1 MHz/11.4 GHz in relative frequency error, which just satisfies the above requirement. To keep this machining precision, the diffusion bonding technique is found preferable to join the cells. Various diffusion conditions were tried. The frequency change can be less than 1 MHz/11.4 GHz and it can be controlled well better than that. (author)

  3. Quantum sized gold nanoclusters with atomic precision.

    Science.gov (United States)

    Qian, Huifeng; Zhu, Manzhou; Wu, Zhikun; Jin, Rongchao

    2012-09-18

    Gold nanoparticles typically have a metallic core, and the electronic conduction band consists of quasicontinuous energy levels (i.e. spacing δ ≪ k(B)T, where k(B)T is the thermal energy at temperature T (typically room temperature) and k(B) is the Boltzmann constant). Electrons in the conduction band roam throughout the metal core, and light can collectively excite these electrons to give rise to plasmonic responses. This plasmon resonance accounts for the beautiful ruby-red color of colloidal gold first observed by Faraday back in 1857. On the other hand, when gold nanoparticles become extremely small (plasmonic gold nanoparticles, researchers often refer to the ultrasmall nanoparticles as nanoclusters. In this Account, we chose several typical sizes of gold nanoclusters, including Au(25)(SR)(18), Au(38)(SR)(24), Au(102)(SR)(44), and Au(144)(SR)(60), to illustrate the novel properties of metal nanoclusters imparted by quantum size effects. In the nanocluster size regime, many of the physical and chemical properties of gold nanoparticles are fundamentally altered. Gold nanoclusters have discrete electronic energy levels as opposed to the continuous band in plasmonic nanoparticles. Quantum-sized nanoparticles also show multiple optical absorption peaks in the optical spectrum versus a single surface plasmon resonance (SPR) peak at 520 nm for spherical gold nanocrystals. Although larger nanocrystals show an fcc structure, nanoclusters often have non-fcc atomic packing structures. Nanoclusters also have unique fluorescent, chiral, and magnetic properties. Due to the strong quantum confinement effect, adding or removing one gold atom significantly changes the structure and the electronic and optical properties of the nanocluster. Therefore, precise atomic control of nanoclusters is critically important: the nanometer precision typical of conventional nanoparticles is not sufficient. Atomically precise nanoclusters are represented by molecular formulas (e.g. Au

  4. Precision velocimetry planet hunting with PARAS: Current performance and lessons to inform future extreme precision radial velocity instruments

    CERN Document Server

    Roy, Arpita; Mahadevan, Suvrath; Chaturvedi, Priyanka; Prasad, Neelam J S S V; Shah, Vishal; Pathan, F M; Anandarao, B G

    2016-01-01

    PARAS is a fiber-fed stabilized high-resolution cross-dispersed echelle spectrograph, located on the 1.2 m telescope in Mt. Abu India. Designed for exoplanet detection, PARAS is capable of single-shot spectral coverage of 3800 - 9600 A, and currently achieving radial velocity (RV) precisions approaching ~1 m/s over several months using simultaneous ThAr calibration. As such, it is one of the few dedicated stabilized fiber-fed spectrographs on small (1-2 m) telescopes that are able to fill an important niche in RV follow-up and stellar characterization. The success of ground-based RV surveys is motivating the push into extreme precisions, with goals of ~10 cm/s in the optical and <1 m/s in the near-infrared (NIR). Lessons from existing instruments like PARAS are invaluable in informing hardware design, providing pipeline prototypes, and guiding scientific surveys. Here we present our current precision estimates of PARAS based on observations of bright RV standard stars, and describe the evolution of the dat...

  5. Curved neutron guide

    International Nuclear Information System (INIS)

    The principle of the curved neutron guide is to transport neutrons far away from the reactor core with as minimum particle loss as possible. After a series of total reflection,the neutron beam is no longer visible from the reactor core and consequently, gamma radiations and fast neutrons emitted from the core are scattered by the walls of the guide and absorbed by the biological shielding set around the guide. The curved neutron guide provides a high-quality beam of slow neutrons. The first chapter deals with the theoretical concept of curved guide, we have determined the parameters for the setting of such a guide in the EL3 reactor at Saclay (France). The different tolerances on the state the surface, on the alignment of the different parts of the guide, on the waving of the guide wall have been assessed. The second chapter presents the technical solution chosen that complies to all the required specifications. The curved neutron guide has been designed for neutrons with wavelength of 4 Angstroms, it is 29 m long, has a bending radius of 835 m and is composed of 87 rectangular components made of glass plates on which a 1500 angstrom thick layer of nickel has been deposited. Each component is set with a fixed angle of (4±0.25)*10-4 radians from the previous component in order to form the bending radius. The last chapter is dedicated to the neutron flux measurement made at the end of the neutron guide

  6. Business Architecture A Practical Guide

    CERN Document Server

    Whelan, Jonathan

    2012-01-01

    Organizations today exist in an environment of unprecedented change. They do so against a backdrop of a global, competitive marketplace, the fast-paced enablement of technology, amplified regulation and accelerating organizational complexity. Many organizations are addressing change in a sub-optimal way and they are operating without a clear view of where their operational risks lie. It is these dynamics that are leading organizations to recognise and embrace Business Architecture.With these challenges in mind, this book provides a practical guide on how to employ Business Architecture and how

  7. MRI survival guide; MRT Basiskurs

    Energy Technology Data Exchange (ETDEWEB)

    Cardoza, J. [Alta Imaging Medical Group and Magnetic Imaging Affiliates, Berkeley, CA (United States); Herfkens, R.J. [eds.] [Stanford Univ., CA (United States). Medical Center

    1999-07-01

    The book is a German translation of an American textbook with the original title ''MRI Survival Guide'' and is intended to serve as an introductory guide for beginners or a reference book for quick information. Readers will find information on the fundamentals of the technology and methodology of MRI as well as all details of relevance to practice in a precise and easy-to-grasp arrangement, covering all anatomic areas of interest, illustrations and descriptions of characteristic signs of pathologic processes, high-quality and unusually large-sized diagnostic pictures, a modern didactic concept for quick orientiation, including surveys, tables, and reproductions for visualisation of contents. (orig./CB) [German] Praktisch jeder Mediziner wird im Laufe seiner Berufstaetigkeit mit der MRT konfrontiert - unabhaengig davon ob in der Radiologie, Orthopaedie, Gynaekologie, Chirurgie, Neurologie oder sonstigen Fachrichtung. Das Buch ist eine Uebersetzung eines amerikanischen Lehrbuches mit dem Originaltitel ''MRI Survival Guide'' und will eine wesentliche Erleichterung als 'Ueberlebenshandbuch fuer die MRT' bieten: - Darstellung aller relevanten Grundlagen zu Technik, verschiedenen Sequenzen und Methodik der MRT - knapp und mit maximalem Praxisbezug - Beruecksichtigung aller moeglichen Untersuchungsregionen und strukturierte Orientierung daran (Gehirn, Wirbelsaeule, Kopf/Nacken, Brustkorb, Bauch, Becken, Muskel-Skelett-Bereich) - Illustration und Beschreibung der charakteristischen Erscheinungsmerkmale aller haeufigen pathologischen Prozesse im MRT, inklusive direkt umsetzbarer differentialdiagnostischer Abgrenzungskriterien - hochwertiges und aussergewoehnlich gross dimensioniertes Bildmaterial - modernes, didaktisches Konzept fuer die rasche Orientierung mit vielen Uebersichten, Tabellen und Abbildungen zur Visualisierung der Inhalte, Praxistips und Aufzeigen von Fehlermoeglichkeiten - zum Einstieg, zur Rekapitulation

  8. High precision anatomy for MEG.

    Science.gov (United States)

    Troebinger, Luzia; López, José David; Lutti, Antoine; Bradbury, David; Bestmann, Sven; Barnes, Gareth

    2014-02-01

    Precise MEG estimates of neuronal current flow are undermined by uncertain knowledge of the head location with respect to the MEG sensors. This is either due to head movements within the scanning session or systematic errors in co-registration to anatomy. Here we show how such errors can be minimized using subject-specific head-casts produced using 3D printing technology. The casts fit the scalp of the subject internally and the inside of the MEG dewar externally, reducing within session and between session head movements. Systematic errors in matching to MRI coordinate system are also reduced through the use of MRI-visible fiducial markers placed on the same cast. Bootstrap estimates of absolute co-registration error were of the order of 1mm. Estimates of relative co-registration error were <1.5mm between sessions. We corroborated these scalp based estimates by looking at the MEG data recorded over a 6month period. We found that the between session sensor variability of the subject's evoked response was of the order of the within session noise, showing no appreciable noise due to between-session movement. Simulations suggest that the between-session sensor level amplitude SNR improved by a factor of 5 over conventional strategies. We show that at this level of coregistration accuracy there is strong evidence for anatomical models based on the individual rather than canonical anatomy; but that this advantage disappears for errors of greater than 5mm. This work paves the way for source reconstruction methods which can exploit very high SNR signals and accurate anatomical models; and also significantly increases the sensitivity of longitudinal studies with MEG. PMID:23911673

  9. High precision anatomy for MEG☆

    Science.gov (United States)

    Troebinger, Luzia; López, José David; Lutti, Antoine; Bradbury, David; Bestmann, Sven; Barnes, Gareth

    2014-01-01

    Precise MEG estimates of neuronal current flow are undermined by uncertain knowledge of the head location with respect to the MEG sensors. This is either due to head movements within the scanning session or systematic errors in co-registration to anatomy. Here we show how such errors can be minimized using subject-specific head-casts produced using 3D printing technology. The casts fit the scalp of the subject internally and the inside of the MEG dewar externally, reducing within session and between session head movements. Systematic errors in matching to MRI coordinate system are also reduced through the use of MRI-visible fiducial markers placed on the same cast. Bootstrap estimates of absolute co-registration error were of the order of 1 mm. Estimates of relative co-registration error were < 1.5 mm between sessions. We corroborated these scalp based estimates by looking at the MEG data recorded over a 6 month period. We found that the between session sensor variability of the subject's evoked response was of the order of the within session noise, showing no appreciable noise due to between-session movement. Simulations suggest that the between-session sensor level amplitude SNR improved by a factor of 5 over conventional strategies. We show that at this level of coregistration accuracy there is strong evidence for anatomical models based on the individual rather than canonical anatomy; but that this advantage disappears for errors of greater than 5 mm. This work paves the way for source reconstruction methods which can exploit very high SNR signals and accurate anatomical models; and also significantly increases the sensitivity of longitudinal studies with MEG. PMID:23911673

  10. A method to improve the precision of measuring focusing system

    Science.gov (United States)

    Xu, Xiaoliang; An, Tao; Chen, Ke

    2015-10-01

    Most of the telescope focusing systems adopt the measuring distance method to focus the quick-moving target because the imaging position of moving target is constantly changing. The focusing system calculates the focal position, controls the motor according to the distance of the target. This focusing method has a faster focusing and a better real-time performance compared to the image focusing method based on the image quality. But restricted by the external environment, the precision of instruments and technical level, Distance measuring focus system(DMFS) generally have low precision, higher dynamic adjusting delay problem. This paper mainly analyses the main error sources affecting the accuracy of DMFS, aiming at the existing defects of commonly used current speed compensation method, put forward a kind of solution path delay lag method predicted method measuring focusing system, and then simulate it, the result shows that this method can greatly improve the precision of DMFS.

  11. Motion and gravity effects in the precision of quantum clocks

    CERN Document Server

    Lindkvist, Joel; Johansson, Göran; Fuentes, Ivette

    2014-01-01

    We show that motion and gravity affect the precision of quantum clocks. We consider a localised quantum field as a fundamental model of a quantum clock moving in spacetime and show that its state is modified due to changes in acceleration. By computing the quantum Fisher information we determine how relativistic motion modifies the ultimate bound in the precision of the measurement of time. While in the absence of motion the squeezed vacuum is the ideal state for time estimation, we find that it is highly sensitive to the motion-induced degradation of the quantum Fisher information. We show that coherent states are generally more resilient to this degradation and that in the case of very low initial number of photons, the optimal precision can be even increased by motion. These results can be tested with current technology by using superconducting resonators with tunable boundary conditions.

  12. Motion and gravity effects in the precision of quantum clocks.

    Science.gov (United States)

    Lindkvist, Joel; Sabín, Carlos; Johansson, Göran; Fuentes, Ivette

    2015-01-01

    We show that motion and gravity affect the precision of quantum clocks. We consider a localised quantum field as a fundamental model of a quantum clock moving in spacetime and show that its state is modified due to changes in acceleration. By computing the quantum Fisher information we determine how relativistic motion modifies the ultimate bound in the precision of the measurement of time. While in the absence of motion the squeezed vacuum is the ideal state for time estimation, we find that it is highly sensitive to the motion-induced degradation of the quantum Fisher information. We show that coherent states are generally more resilient to this degradation and that in the case of very low initial number of photons, the optimal precision can be even increased by motion. These results can be tested with current technology by using superconducting resonators with tunable boundary conditions. PMID:25988238

  13. Elastic guides reduce hysteresis effect in Belleville spring package

    Science.gov (United States)

    Mc Glashan, W. F., Jr.; Toth, L. R.

    1967-01-01

    Peripheral support guides that elastically flex with the slight breathing on radial displacement during actuation can greatly reduce the hysteresis present in a Belleville spring package. This technique provides a control device that enhances the precision of pressure regulating valves, pressure switches, and vacuum actuators.

  14. Maven The Definitive Guide

    CERN Document Server

    Company, Sonatype

    2009-01-01

    Written by Maven creator Jason Van Zyl and his team at Sonatype, Maven: The Definitive Guide clearly explains how this popular tool can bring order to your software development projects. The first part of the book demonstrates Maven's capabilities through the development of several sample applications from ideation to deployment, and the second part offers a complete reference guide. Concise and to the point, this is the only guide you need to manage your project.

  15. Joomla! 3 beginner's guide

    CERN Document Server

    Tiggeler, Eric

    2014-01-01

    An easy to use, step-by-step guide to creating professional, mobile-friendly websites with the free Joomla CMS. The Joomla! 3 Beginner's Guide Second Edition is the ultimate guide for web developers who wish to build upon their skills and knowledge on creating websites. Even if you're new to this subject, you won't have any difficulty understanding the clear and friendly instructions and explanations. No prior knowledge of HTML and CSS is required.

  16. CISSP study guide

    CERN Document Server

    Conrad, Eric; Feldman, Joshua; Riggins, Kevin

    2011-01-01

    "The Eleventh Hour CISSP Study Guide" is keyed to the latest CISSP exam. This book is streamlined to include only core certification information and is presented for ease of last-minute studying. Main objectives of the exam are covered concisely with key concepts highlighted. This is the only guide you need for last-minute studying. This title answers the toughest questions and highlights core topics. This title can be paired with any other study guide so you are completely prepared.

  17. Relativistic Guiding Center Equations

    Energy Technology Data Exchange (ETDEWEB)

    White, R. B. [PPPL; Gobbin, M. [Euratom-ENEA Association

    2014-10-01

    In toroidal fusion devices it is relatively easy that electrons achieve relativistic velocities, so to simulate runaway electrons and other high energy phenomena a nonrelativistic guiding center formalism is not sufficient. Relativistic guiding center equations including flute mode time dependent field perturbations are derived. The same variables as used in a previous nonrelativistic guiding center code are adopted, so that a straightforward modifications of those equations can produce a relativistic version.

  18. Sensor Characteristics Reference Guide

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-04-01

    The purpose of the guide is to inform building owners and operators of the current status, capabilities, and limitations of sensor technologies. It is hoped that this guide will aid in the design and procurement process and result in successful implementation of building sensor and control systems. DOE will also use this guide to identify research priorities, develop future specifications for potential market adoption, and provide market clarity through unbiased information.

  19. Precision Medicine, Cardiovascular Disease and Hunting Elephants.

    Science.gov (United States)

    Joyner, Michael J

    2016-01-01

    Precision medicine postulates improved prediction, prevention, diagnosis and treatment of disease based on patient specific factors especially DNA sequence (i.e., gene) variants. Ideas related to precision medicine stem from the much anticipated "genetic revolution in medicine" arising seamlessly from the human genome project (HGP). In this essay I deconstruct the concept of precision medicine and raise questions about the validity of the paradigm in general and its application to cardiovascular disease. Thus far precision medicine has underperformed based on the vision promulgated by enthusiasts. While niche successes for precision medicine are likely, the promises of broad based transformation should be viewed with skepticism. Open discussion and debate related to precision medicine are urgently needed to avoid misapplication of resources, hype, iatrogenic interventions, and distraction from established approaches with ongoing utility. Failure to engage in such debate will lead to negative unintended consequences from a revolution that might never come. PMID:26902518

  20. Study on noise of precision panel saw

    Institute of Scientific and Technical Information of China (English)

    HUWan-yi; QIYing-jie; ZHANGZhao-hao; QIXiao-jie

    2003-01-01

    According to ZBJ65015-89 standard about noise level testing method of woodworking toot, the noise testing for MJg0# and MJCl125 precision panel saws was conducted by using model ND2 precision soundqevel apparatus and double frequency wave filter. The testing results showed that the unloaded running noise source of precision panel saw was mainly from main saw blade and its aeromechanic noise was the largest. The rotating speed was determined as an important factor to impact dynamic characters of precision panel saw as the unloaded running noise increased along with speed increasing. For reducing noise of precision panel saw, the first important way is to reduce the aeromechanic noise produced by main saw blade rotating at high speed; based on assuring the processing precision, choosing tow speed is a better way to drop dawn noise; from the view of design, the diameter of clamping lid is better of half of outer diameter of main saw blade.

  1. Interactions between science and precision engineering

    Science.gov (United States)

    Atkinson, D. P.; McClure, E. R.; Saito, T. T.

    1987-11-01

    The history of scientific progress is intertwined intimately with precision engineering. Precision engineering and science have synergistically interacted in stimulating each other to significant advances. Furthermore, tangible benefits to the quality of human life, through often unexpected industrial applications, occur. High energy lasers, astrophysical telescopes, and anamorphic optics, along with developments in ultraprecision machining and measurement, are discussed as examples of evolution in science and precision engineering. Possibilities for ultimate by-products for mankind's welfare are explored.

  2. New methods for precision Moeller polarimetry*

    International Nuclear Information System (INIS)

    Precision electron beam polarimetry is becoming increasingly important as parity violation experiments attempt to probe the frontiers of the standard model. In the few GeV regime, Moeller polarimetry is well suited to high-precision measurements, however is generally limited to use at relatively low beam currents (<10 μA). We present a novel technique that will enable precision Moeller polarimetry at very large currents, up to 100 μA. (orig.)

  3. New methods for precision Moeller polarimetry

    International Nuclear Information System (INIS)

    Precision electron beam polarimetry is becoming increasingly important as parity violation experiments attempt to probe the frontiers of the standard model. In the few GeV regime, Moeller polarimetry is well suited to high-precision measurements, however is generally limited to use at relatively low beam currents (< 10 (micro)A). We present a novel technique that will enable precision Moeller polarimetry at very large currents, up to 100 (micro)A

  4. Modeling and control of precision actuators

    CERN Document Server

    Kiong, Tan Kok

    2013-01-01

    IntroductionGrowing Interest in Precise ActuatorsTypes of Precise ActuatorsApplications of Precise ActuatorsNonlinear Dynamics and ModelingHysteresisCreepFrictionForce RipplesIdentification and Compensation of Preisach Hysteresis in Piezoelectric ActuatorsSVD-Based Identification and Compensation of Preisach HysteresisHigh-Bandwidth Identification and Compensation of Hysteretic Dynamics in Piezoelectric ActuatorsConcluding RemarksIdentification and Compensation of Frict

  5. Precision Agriculture Technology Adoption for Cotton Production

    OpenAIRE

    Paxton, Kenneth W.; Mishra, Ashok K.; Chintawar, Sachin; Larson, James A.; Roberts, Roland K.; English, Burton C.; Lambert, Dayton M.; Marra, Michele C.; Larkin, Sherry L.; Reeves, Jeanne M.; Martin, Steven W

    2010-01-01

    Many studies on the adoption of precision technologies have generally used logit models to explain the adoption behavior of individuals. This study investigates factors affecting the number of specific types of precision agriculture technologies adopted by cotton farmers. Particular attention is given to the influence of spatial yield variability on the number of precision farming technologies adopted, using a Count data estimation procedure and farm-level data. Results indicate that farmers ...

  6. Precision Higgs boson measurement at CLIC

    CERN Document Server

    Pandurovic, Mila

    2016-01-01

    The design of the next generation collider in high energy physics will primarily focus on the possibility to achieve high precision of the measurements of interest. The necessary precision limits are set, in the first place, by the measurement of the Higgs boson but also by measurements that are sensitive to signs of New Physics. The Compact Linear Collider (CLIC) is an attractive option for a future multi-TeV linear electron-positron collider, with the potential to cover a rich physics program with high precision. In this lecture the CLIC accelerator, detector and backgrounds will be presented with emphesis on the capabilities of CLIC for precision Higgs physics.

  7. 胸部放射治疗中锥形束CT与MOSAIQ系统中电子射野影像的图像配准精度比较%Comparison of the Precision of Cone Beam CT and Electronic Portal Image Device in Guiding the Radiation Therapy for Thorax Tumor

    Institute of Scientific and Technical Information of China (English)

    李晓玉; 钟仁明; 安卫军; 何垠波; 罗彩怡

    2012-01-01

    Objective To compare the cone beam CT (CBCT) and electronic portal image device (EPID) in measuring the positioning errors in guiding thorax tumor radiotherapy. Methods From February to September 2011, CBCT images and EPID images were acquired respectively for 21 patients with thorax tumor who received intensity-modulated radiation therapy (IMRT) immobilized by thermoplastic. The CBCT images were aligned with simulation planning CT images. The EPID images were acquired by anterior-posterior direction and right-left direction, which were transported to MOSAIQ system and aligned with digital reconstructed radiography (DRR) images generated by the planning system. These aligned results for CBCT images in right-left, inferior-superior and anterior-posterior directions for translation error and X, Y and Z direction for rotation error were calculated to means and standard deviations, and we compared the means with aligned results for EPID. The rotation errors for EPID images were neglected. Results A total of 106 paired samples of CBCT images and EPID images were acquired and analyzed. The translation errors for CBCT images and EPID images were (-0.103 ± 0.240) cm, (-0.086 ± 0.342) cm, (0.017 ± 0184) cm and (0.005 ± 0.214) cm, (-0.004 ± 0.0.315) cm, (-0.113 ± 0.239) cm respectively. The rotation error in X, Y and Z direction for CBCT images were (0.792 ± 1.173)°, (-0.130 ±1.407)° and (0.793 ± 0.960)° respectively. The possibility for ≤ 3° in rotation errors were 98.2%, 97.2%, and 99.1%. The P value of paired sample t test for aligned results of CBCT images and EPID images was > 0.05 in Y direction and < 0.05 in X and Z directions. There was a negative line correlation between these two systems. Conclusion There is a significant difference between aligned results of CBCT and EPID systems, which indicates that CBCT is a primary choice for image guiding if available.%目的 分析比较锥形束CT(CBCT)与MOSAIQ两系统用于测量胸部放射治疗(放

  8. Abbreviated guide pneumatic conveying design guide

    CERN Document Server

    Mills, David

    1990-01-01

    Abbreviated Guide: Pneumatic Conveying Design Guide describes the selection, design, and specification of conventional pneumatic conveying systems. The design procedure uses previous test data on the materials to be conveyed. The book also discusses system economics, operating costs, the choice of appropriate components or systems, system control, and system flexibility. The design system involves the type of conveying system for installation, the pipeline parameters, and also the plant components. System selection covers the properties of the material to be conveyed, plant layout, material pr

  9. Experiments in cold atom optics towards precision atom interferometry

    Science.gov (United States)

    Aveline, David C.

    Atom optics has been a highly active field of research with many scientific breakthroughs over the past two decades, largely due to successful advances in laser technology, microfabrication techniques, and the development of laser cooling and trapping of neutral atoms. This dissertation details several atom optics experiments with the motivation to develop tools and techniques for precision atom wave interferometry. It provides background information about atom optics and the fundamentals behind laser cooling and trapping, including basic techniques for cold gas thermometry and absorptive detection of atoms. A brief overview of magnetic trapping and guiding in tight wire-based traps is also provided before the experimental details are presented. We developed a novel laser source of 780 nm light using frequency-doubled 1560 nm fiber amplifier. This laser system provided up to a Watt of tunable frequency stabilized light for two Rb laser cooling and trapping experiments. One system generates Bose-Einstein condensates in an optical trap while the second is based on atom chip magnetic traps. The atom chip system, detailed in this thesis, was designed and built to develop the tools necessary for transport and loading large numbers of cold atoms and explore the potential for guided atom interferometry. Techniques and results from this experiment are presented, including an efficient magnetic transport and loading method to deliver cold atom to atom chip traps. We also developed a modeling tool for the magnetic fields formed by coiled wire geometries, as well as planar wire patterns. These models helped us design traps and determine adiabatic transportation of cold atoms between macro-scale traps and micro-traps formed on atom chips. Having achieved near unity transfer efficiency, we demonstrated that this approach promises to be a consistent method for loading large numbers of atoms into micro-traps. Furthermore, we discuss an in situ imaging technique to investigate

  10. Solutions for Subject Guides

    OpenAIRE

    Donald Moses; Jennifer Richard

    2008-01-01

    The following article describes two libraries' experiences with the implementation of newsoftware packages to deliver timely, accurate and dynamic content via library subjectguides. Acadia University in Wolfville, Nova Scotia implemented new subject guidesusing LibGuides in 2007 and Holland College in Charlottetown, PEI recently launchedtheir new guides in the fall of 2008 using SubjectsPlus.

  11. Native Americans: Subject Guide.

    Science.gov (United States)

    Bonanni, Mimmo; Etter, Patricia A.

    This annotated subject guide lists reference material that deals with Native Americans and is available in the Arizona State University Libraries. Entries were published 1933-98, but mostly in the 1980s-90s. The guide is not comprehensive, but rather a selective list of resources useful for researching a topic in a variety of fields. The guide…

  12. Solutions for Subject Guides

    Directory of Open Access Journals (Sweden)

    Donald Moses

    2008-12-01

    Full Text Available The following article describes two libraries' experiences with the implementation of newsoftware packages to deliver timely, accurate and dynamic content via library subjectguides. Acadia University in Wolfville, Nova Scotia implemented new subject guidesusing LibGuides in 2007 and Holland College in Charlottetown, PEI recently launchedtheir new guides in the fall of 2008 using SubjectsPlus.

  13. Irrigation Systems. Instructor's Guide.

    Science.gov (United States)

    Amarillo Coll., TX.

    This guide is intended for use by licensed irrigators who wish to teach others how to design and install residential and commercial irrigation systems. The materials included in the guide have been developed under the assumption that the instructors who use it have little or no formal training as teachers. The first section presents detailed…

  14. Irrigation Systems. Student's Guide.

    Science.gov (United States)

    Amarillo Coll., TX.

    This guide is intended for use by individuals preparing for a career in commercial and residential irrigation. The materials included are geared toward students who have had some experience in the irrigation business; they are intended to be presented in 10 six-hour sessions. The first two sections deal with using this guide and preparing for the…

  15. Guided Reading and Motivation

    Science.gov (United States)

    Hauptman, Allyson L.

    2012-01-01

    The purpose of this study was to determine the relationship between Guided Reading and student motivation to read across fourth, fifth, and sixth grades. The study defined literacy motivation as: (a) task value; (b) self-perceived competence; (c) students' perceptions of the Guided Reading format. Factor analysis and repeated measures ANOVAs were…

  16. Kompetencevurdering - en guide

    DEFF Research Database (Denmark)

    Andersen, Ole Dibbern; Larsen, Verner

    Publikationen er en praktisk guide til erhvervsskolernes arbejde med kompetencevurdering, og anviser metoder og angrebsvinkler på arbejdet med at afdække elevers kompetencer ved indgangen til erhvervsuddannelse......Publikationen er en praktisk guide til erhvervsskolernes arbejde med kompetencevurdering, og anviser metoder og angrebsvinkler på arbejdet med at afdække elevers kompetencer ved indgangen til erhvervsuddannelse...

  17. Credit Reporting Knowledge Guide

    OpenAIRE

    International Finance Corporation

    2012-01-01

    This second edition of the Credit Reporting Knowledge Guide aims to support the dissemination of knowledge on best practices in credit reporting development, based on IFC s experience. The original Credit Bureau Knowledge Guide (2006) elaborated on the knowledge gained over several years of running the Global Credit Reporting Progra

  18. Measurement Practice Guide

    Science.gov (United States)

    College and Career Readiness and Success Center, 2014

    2014-01-01

    This discussion guide is part of a larger practice guide designed to help state education agencies (SEAs) define measurement goals, select college and career readiness measures and indicators designed to support those goals, and use the data gathered with those measures and indicators to make informed decisions about college and career readiness…

  19. Visualizing guided tours

    DEFF Research Database (Denmark)

    Poulsen, Signe Herbers; Fjord-Larsen, Mads; Hansen, Frank Allan;

    This paper identifies several problems with navigating and visualizing guided tours in traditional hypermedia systems. We discuss solutions to these problems, including the representation of guided tours as 3D metro maps with content preview. Issues regarding navigation and disorientation are...

  20. Nutrition Guide for Toddlers

    Science.gov (United States)

    ... Story" 5 Things to Know About Zika & Pregnancy Nutrition Guide for Toddlers KidsHealth > For Parents > Nutrition Guide ... español Guía de nutrición para sus hijos pequeños Nutrition Through Variety Growth slows somewhat during the toddler ...

  1. Library Automation Style Guide.

    Science.gov (United States)

    Gaylord Bros., Liverpool, NY.

    This library automation style guide lists specific terms and names often used in the library automation industry. The terms and/or acronyms are listed alphabetically and each is followed by a brief definition. The guide refers to the "Chicago Manual of Style" for general rules, and a notes section is included for the convenience of individual…

  2. concrete5 Beginner's Guide

    CERN Document Server

    Laubacher, Remo

    2011-01-01

    This book is part of Packt's Beginner's Guide series. You will be guided through the set up of a Concrete5 site with step-by-step practical examples. This book is ideal for developers who would like to build their first site with Concrete5. Some k

  3. JBoss ESB Beginner's Guide

    CERN Document Server

    DiMaggio, Len; Magesh, Kumar

    2012-01-01

    Part of Packt's Beginner's Guide series, each chapter contains practical examples with step-by-step instructions and plenty of screenshots to guide you through the implementation of JBoss ESB. This book is intended for Java programmers although you don't need previous experience with middleware such as application servers or ESBs.

  4. Conquistadors. Teaching Guide.

    Science.gov (United States)

    Larson, Susan Booth

    This teaching guide is comprised of four interdisciplinary units dealing with the expeditions of conquistadors in the New World: (1) "Cortes and the Aztecs: Different Views of the World"; (2) "Pizarro and the Incas: The 'What Ifs?' of History"; (3) "Orellana and the Amazon: Human and Environmental Issues"; and (4) "Teaching Guide for Cabeza de…

  5. The Higgs hunter's guide

    CERN Document Server

    Gunion, John F; Haber, Howard E; Kane, Gordon L

    1989-01-01

    The Higgs Hunter's Guide is a definitive and comprehensive guide to the physics of Higgs bosons. In particular, it discusses the extended Higgs sectors required by those recent theoretical approaches that go beyond the Standard Model, including supersymmetry and superstring-inspired models.

  6. Marketing Education Curriculum Guide.

    Science.gov (United States)

    Michigan State Univ., East Lansing. Coll. of Agriculture and Natural Resources Education Inst.

    This curriculum guide is intended to provide a common core of competencies from which to design an effective secondary marketing education program. Introductory materials include a definition of marketing education, objectives, outline of instructional content, and questions and answers regarding the curriculum guide. These practical materials are…

  7. Curriculum Guide Construction Cluster.

    Science.gov (United States)

    Kline, Ken

    As part of a model construction cluster curriculum development project, this guide was developed and implemented in the Beaverton (Oregon) School District. The curriculum guide contains 16 units covering the following topics: introduction to construction jobs; safety and first aid; blueprint readings; basic mathematics; site work; framing; roofing…

  8. Hospitality Services. Curriculum Guide.

    Science.gov (United States)

    Texas Tech Univ., Lubbock. Home Economics Curriculum Center.

    This guide, which was developed as part of Texas' home economics education program, is intended to assist teachers of a hospitality services course focusing on the food and lodging segments of the hospitality and tourism industry. The first 40% of the approximately 600-page guide consists of strategies for teaching each of 29 essential…

  9. Instructional Guide for Cosmetology.

    Science.gov (United States)

    Virginia Polytechnic Inst. and State Univ., Blacksburg. Dept. of Education.

    Intended as a tool for cosmetology teachers in Virginia public and private schools, the document is an instructional guide which offers 12 units of study, arranged in a three year course. Materials covered help prepare students for licensure in the State of Virginia and the guide is designed to cover the 1,500 hours required to be spent in the…

  10. Drafting Lab Management Guide.

    Science.gov (United States)

    Ohio State Univ., Columbus. Instructional Materials Lab.

    This manual was developed to guide drafting instructors and vocational supervisors in sequencing laboratory instruction and controlling the flow of work for a 2-year machine trades training program. The first part of the guide provides information on program management (program description, safety concerns, academic issues, implementation…

  11. Adaptive Human Control Gains During Precision Grip

    Directory of Open Access Journals (Sweden)

    Erik D. Engeberg

    2013-03-01

    Full Text Available Eight human test subjects attempted to track a desired position trajectory with an instrumented manipulandum (MN. The test subjects used the MN with three different levels of stiffness. A transfer function was developed to represent the human application of a precision grip from the data when the test subjects initially displaced the MN so as to learn the position mapping from the MN onto the display. Another transfer function was formed from the data of the remainder of the experiments, after significant displacement of the MN occurred. Both of these transfer functions accurately modelled the system dynamics for a portion of the experiments, but neither was accurate for the duration of the experiments because the human grip dynamics changed while learning the position mapping. Thus, an adaptive system model was developed to describe the learning process of the human test subjects as they displaced the MN in order to gain knowledge of the position mapping. The adaptive system model was subsequently validated following comparison with the human test subject data. An examination of the average absolute error between the position predicted by the adaptive model and the actual experimental data yielded an overall average error of 0.34mm for all three levels of stiffness.

  12. Little Higgs and precision electroweak tests

    OpenAIRE

    Deandrea, Aldo

    2004-01-01

    I consider the low energy limit of Little Higgs models. The method consists in eliminating the heavy fields using their classical equations of motion in the infinite mass limit. After the elimination of the heavy degrees of freedom one can directly read off deviations from the precision electroweak data. I also examine the effects on the low energy precision experiments.

  13. Little Higgs Models and Precision Electroweak Data

    OpenAIRE

    Casalbuoni, Roberto; Deandrea, Aldo; Oertel, Micaela

    2003-01-01

    We study the low energy limit of Little Higgs models. The method consists in eliminating the heavy fields using their classical equations of motion in the infinite mass limit. After the elimination of the heavy degrees of freedom we can directly read off deviations from the precision electroweak data. We also examine the effects on the low energy precision experiments.

  14. Analysis of Precision of Activation Analysis Method

    DEFF Research Database (Denmark)

    Heydorn, Kaj; Nørgaard, K.

    1973-01-01

    The precision of an activation-analysis method prescribes the estimation of the precision of a single analytical result. The adequacy of these estimates to account for the observed variation between duplicate results from the analysis of different samples and materials, is tested by the statistic T...

  15. Ultra-precision processes for optics manufacturing

    Science.gov (United States)

    Martin, William R.

    1991-12-01

    The Optics MODIL (Manufacturing Operations Development and Integration Laboratory) is developing advanced manufacturing technologies for fabrication of ultra precision optical components, aiming for a ten-fold improvement in precision and a shortening of the scheduled lead time. Current work focuses on diamond single point turning, ductile grinding, ion milling, and in/on process metrology.

  16. Remote sensing applications to precision farming

    Science.gov (United States)

    Traditional mechanized agriculture treats large fields with uniform agronomic practices. Precision agriculture/precision farming brings a new concept to manage in-field variability with variable rate application of fertilizers and pesticides, site-specific water management, as well as planting, etc....

  17. The Value of Information in Precision Farming

    OpenAIRE

    Liu, Xuanli; Nelson, Macon; Ibrahim, Mohammed

    2008-01-01

    This study examines how the value of information is measured and its role in precision farming. Two types of precision farming are discussed regarding information in use and ways of information collection. Analytical equations have been derived to link the estimation of the value of information to limited parameters available.

  18. Precision correlation measurements in nuclear β decay

    International Nuclear Information System (INIS)

    Precision measurements in nuclear β decay provide a sensitive means of searching for new physics beyond the standard electroweak model. This paper reviews the status of selected precision measurements of correlation observables in nuclear and neutron β decay and discusses the prospects and future plans.

  19. Human factors guides

    International Nuclear Information System (INIS)

    This document presents human factors guides, which have been developed in order to provide licensees of the AECB with advice as to how to address human factors issues within the design and assessment process. This documents presents the results of a three part study undertaken to develop three guides which are enclosed in this document as Parts B, C and D. As part of the study human factors standards, guidelines, handbooks and other texts were researched, to define those which would be most useful to the users of the guides and for the production of the guides themselves. Detailed specifications were then produced to outline the proposed contents and format of the three guides. (author). 100 refs., 3 tabs., 11 figs

  20. Manual on brachytherapy. Incorporating: Applications guide, procedures guide, basics guide

    International Nuclear Information System (INIS)

    This publication is part of practical radiation safety manual series for different fields of application aimed primarily at persons handling radiation sources on a daily routine basis, which could at same time be used by the competent authorities, supporting their efforts in the radiation protection training of workers or medical assistance personnel or helping on-site management to set up local radiation protection rules. It is dedicated to brachytherapy: its application and procedures guides

  1. Design of the Mechanical Parts for the Neutron Guide System at HANARO

    Science.gov (United States)

    Shin, J. W.; Cho, Y. G.; Cho, S. J.; Ryu, J. S.

    2008-03-01

    The research reactor HANARO (High-flux Advanced Neutron Application ReactOr) in Korea will be equipped with a neutron guide system, in order to transport cold neutrons from the neutron source to the neutron scattering instruments in the neutron guide hall near the reactor building. The neutron guide system of HANARO consists of the in-pile plug assembly with in-pile guides, the primary shutter with in-shutter guides, the neutron guides in the guide shielding room with dedicated secondary shutters, and the neutron guides connected to the instruments in the neutron guide hall. Functions of the in-pile plug assembly are to shield the reactor environment from nuclear radiation and to support the neutron guides and maintain them precisely oriented. The primary shutter is a mechanical structure to be installed just after the in-pile plug assembly, which stops neutron flux on demand. This paper describes the design of the in-pile assembly and the primary shutter for the neutron guide system at HANARO. The design of the guide shielding assembly for the primary shutter and the neutron guides is also presented.

  2. Guidebook for territories' support in the analysis of their socio-economical vulnerability to climate change; Guide d'accompagnement des territoires pour l'analyse de leur vulnerabilite socio-economique au changement climatique

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The work of the inter-ministerial group 'Impacts of Climate Change, Adaptation and Associated Costs for France', which met between March 2007 and October 2009, led to a sector-based assessment of all climate change related impacts and of associated adaptation measures. The aim was to obtain quantified elements that could underpin public policy decision-making and especially development of the National Adaptation Plan. While the sectoral analyses focused on quantifying the costs of adaptation, the approach of the 'Territories' group, co-steered by the Datar (regional development delegation) and Ademe (agency for energy management and environment), addressed the subject of interactions between players and activities, both spatial (sharing of resources between different uses, etc.) and temporal (transition from one situation to another, etc.) and the corresponding means for adjustment. It was in this context that the SOeS proposed a methodology for diagnosis of the socio-economic vulnerability of a given sub-national territory in the face of climate change. This document provides a broad-brush outline of the accompanying guidelines developed by Sogreah Consultants SAS for use by local players. A three step approach is followed to draw up the vulnerability profile of a territory: 1 - characterising the territory by the identification of the priority activities and physical features; 2 - using the analysis tools to produce a matrix of indices of vulnerability to climate change per hazard; 3 - drawing up an initial vulnerability profile by bringing together the information from the matrix and that from feedback, either by activity or group of activities, or by environment, depending on aims. The profile leads to identification of the important issues as well as allowing identification of potential impacts to be studied in more depth. Guidelines were tested in three pilot territories facing different climate change issues: Wateringues, in the Nord

  3. Precision surveying the principles and geomatics practice

    CERN Document Server

    Ogundare, John Olusegun

    2016-01-01

    A comprehensive overview of high precision surveying, including recent developments in geomatics and their applications This book covers advanced precision surveying techniques, their proper use in engineering and geoscience projects, and their importance in the detailed analysis and evaluation of surveying projects. The early chapters review the fundamentals of precision surveying: the types of surveys; survey observations; standards and specifications; and accuracy assessments for angle, distance and position difference measurement systems. The book also covers network design and 3-D coordinating systems before discussing specialized topics such as structural and ground deformation monitoring techniques and analysis, mining surveys, tunneling surveys, and alignment surveys. Precision Surveying: The Principles and Geomatics Practice: * Covers structural and ground deformation monitoring analysis, advanced techniques in mining and tunneling surveys, and high precision alignment of engineering structures *...

  4. Electrician's Helper. Coordinator's Guide. Individualized Study Guide.

    Science.gov (United States)

    Stotts, Danny

    This guide is designed to assist teacher-coordinators supervising cooperative education programs for electrician's helpers in helping students complete a set of individualized, competency-based training activities dealing with electricity and electrical circuits and equipment. The first part of the manual includes a progress chart, a study guide…

  5. Precise monitoring of global temperature trends from satellites

    Science.gov (United States)

    Spencer, Roy W.; Christy, John R.

    1990-01-01

    Passive microwave radiometry from satellites provides more precise atmospheric temperature information than that obtained from the relatively sparse distribution of thermometers over the earth's surface. Accurate global atmospheric temperature estimates are needed for detection of possible greenhouse warming, evaluation of computer models of climate change, and for understanding important factors in the climate system. Analysis of the first 10 years (1979 to 1988) of satellite measurements of lower atmospheric temperature changes reveals a monthly precision of 0.01 C, large temperature variability on time scales from weeks to several years, but no obvious trend for the 10-year period. The warmest years, in descending order, were 1987, 1988, 1983, and 1980. The years 1984, 1985, and 1986 were the coolest.

  6. Aerodynamic window for high precision laser drilling

    Science.gov (United States)

    Sommer, Steffen; Dausinger, Friedrich; Berger, Peter; Hügel, Helmuth

    2007-05-01

    High precision laser drilling is getting more and more interesting for industry. Main applications for such holes are vaporising and injection nozzles. To enhance quality, the energy deposition has to be accurately defined by reducing the pulse duration and thereby reducing the amount of disturbing melting layer. In addition, an appropriate processing technology, for example the helical drilling, yields holes in steel at 1 mm thickness and diameters about 100 μm with correct roundness and thin recast layers. However, the processing times are still not short enough for industrial use. Experiments have shown that the reduction of the atmospheric pressure down to 100 hPa enhances the achievable quality and efficiency, but the use of vacuum chambers in industrial processes is normally quite slow and thus expensive. The possibility of a very fast evacuation is given by the use of an aerodynamic window, which produces the pressure reduction by virtue of its fluid dynamic features. This element, based on a potential vortex, was developed and patented as out-coupling window for high power CO II lasers by IFSW 1, 2, 3. It has excellent tightness and transmission properties, and a beam deflection is not detectable. The working medium is compressed air, only. For the use as vacuum element for laser drilling, several geometrical modifications had to be realized. The prototype is small enough to be integrated in a micromachining station and has a low gas flow. During the laser pulse, which is focussed through the potential flow, a very high fluence is reached, but the measurements have not shown any beam deflection or focal shifting. The evacuation time is below 300 ms so that material treatment with changing ambient pressure is possible, too. Experimental results have proven the positive effect of the reduced ambient pressure on the drilling process for the regime of nano- and picosecond laser pulses. Plasma effects are reduced and, because of the less absorption, the

  7. A practical guide to the Freedom of Information Act 2000

    OpenAIRE

    HOLSEN, S.; Amos, J.

    2004-01-01

    The Constitution Unit has rewritten the Practical Guide to the Freedom of Information Act 2000. The revised edition differs considerably from the original in format and content. Foremest among the changes are the three case studies (with comments) at the end and the references to recently published, more detailed official advice. The guide is designed for practitioners who are responsible for or otherwise involved in their authority's plans to implement and operate the FoI Act. The guide serv...

  8. Pushing the limits of high-precision radiocarbon measurements

    International Nuclear Information System (INIS)

    Accelerator Mass Spectrometry (AMS) is mostly used for radiocarbon dating, because it allows determining efficiently 14C without isobaric or molecular background. While for many years these measurements were performed on large tandem accelerators (3 - 6 MV), this has changed over the last 10 years and compact AMS systems (2 and allows for the first time precise routine radiocarbon dating of micro-gram samples. The impact of the new-generation compact radiocarbon dating systems is discussed.

  9. Precision crystal alignment for high-resolution electron microscope imaging

    International Nuclear Information System (INIS)

    One of the more difficult tasks involved in obtaining quality high-resolution electron micrographs is the precise alignment of a specimen into the required zone. The current accepted procedure, which involves changing to diffraction mode and searching for symmetric point diffraction pattern, is insensitive to small amounts of misalignment and at best qualitative. On-line analysis of the fourier space representation of the image, both for determining and correcting crystal tilt, is investigated. 8 refs., 42 figs

  10. SAGE 1 data user's guide

    International Nuclear Information System (INIS)

    A guide for using the data products from the Stratospheric Aerosol and Gas Experiment 1 (SAGE 1) for scientific investigations of stratospheric chemistry related to aerosol, ozone, nitrogen dioxide, dynamics, and climate change is presented. A detailed description of the aerosol profile tape, the ozone profile tape, and the nitrogen dioxide profile tape is included. These tapes are the SAGE 1 data products containing aerosol extinction data and ozone and nitrogen dioxide concentration data for use in the different scientific investigations. Brief descriptions of the instrument operation, data collection, processing, and validation, and some of the scientific analyses that were conducted are also included

  11. CCNA Wireless Study Guide

    CERN Document Server

    Lammle, Todd

    2010-01-01

    A complete guide to the CCNA Wireless exam by leading networking authority Todd Lammle. The CCNA Wireless certification is the most respected entry-level certification in this rapidly growing field. Todd Lammle is the undisputed authority on networking, and this book focuses exclusively on the skills covered in this Cisco certification exam. The CCNA Wireless Study Guide joins the popular Sybex study guide family and helps network administrators advance their careers with a highly desirable certification.: The CCNA Wireless certification is the most respected entry-level wireless certification

  12. Helsinki Startup City Guide

    OpenAIRE

    Babet, Addou

    2016-01-01

    This thesis is a product-oriented thesis. The aim of the thesis is to create valuable and quality content for the commissioning party, StartUs. The content is educational and takes form as a guide. The guide was done with the support of Haaga-Helia StartUp School. The theoretical framework consists of startup and content marketing theory, and is essential in providing the reader of this thesis the understanding of why the guide is important for the commissioning party and its target audie...

  13. 2015 Australasian sky guide

    CERN Document Server

    Lomb, Nick

    2014-01-01

    Compact, easy to use and reliable, this popular guide has been providing star gazers with everything they need to know about the southern night sky for the past 25 years. The 2015 guide will celebrate this landmark with highlights from the past as well as monthly astronomy maps, viewing tips and highlights, and details of the year's exciting celestial events.Wherever you are in Australia or New Zealand, easy calculations allow you to estimate local rise and set times for the Sun, Moon and planets. The 2015 Australasian Sky Guide also provides information on the solar system, updated with the l

  14. 2014 Australasian sky guide

    CERN Document Server

    Lomb, Nick

    2013-01-01

    Compact, easy to use and reliable, this popular guide contains everything you need to know about the southern night sky with monthly astronomy maps, viewing tips and highlights, and details of all the year's exciting celestial events. Wherever you are in Australia or New Zealand, easy calculations allow you to estimate local rise and set times for the Sun, Moon and planets. The 2014 Australasian Sky Guide also provides information on the solar system, updated with the latest findings from space probes. Published annually since 1991, the Sky Guide continues to be a favourite with photographers,

  15. Precision Polarimetry at the International Linear Collider

    OpenAIRE

    Helebrant, C.; Käfer, D.; List, J.(Deutsches Elektronen Synchrotron (DESY), Hamburg und Zeuthen, 22603, Hamburg, Germany)

    2008-01-01

    The International Linear Collider (ILC) will collide polarised electrons and positrons at beam energies of 45.6 GeV to 250 GeV and optionally up to 500 GeV. To fully exploit the physics potential of this machine, not only the luminosity and beam energy have to be known precisely, but also the polarisation of the particles has to be measured with an unprecedented precision of dP/P ~ 0.25% for both beams. An overall concept of high precision polarisation measurements at high beam energies will ...

  16. Precision gauge unification in the MSSM

    Energy Technology Data Exchange (ETDEWEB)

    Raby, Stuart, E-mail: raby@pacific.mps.ohio-state.ed [Department of Physics, Ohio State University, 191 W. Woodruff Ave, Columbus, OH 43210 (United States); Ratz, Michael, E-mail: mratz@ph.tum.d [Physik-Department T30, Technische Universitaet Muenchen, James-Franck-Strasse, 85748 Garching (Germany); Schmidt-Hoberg, Kai, E-mail: kai.schmidt-hoberg@ph.tum.d [Physik-Department T30, Technische Universitaet Muenchen, James-Franck-Strasse, 85748 Garching (Germany)

    2010-04-19

    We discuss the issue of precision gauge unification in the MSSM. We find that a comparably light gluino, as it emerges in certain patterns of soft supersymmetry breaking, can be a key ingredient for ensuring precision gauge unification without relying on the presence of extra particles around the scale of grand unification. In particular, the so-called mirage pattern for gaugino masses can naturally lead to precision gauge unification. There is also an interesting correlation with reduced fine-tuning, due to rather light gluinos.

  17. Precision gauge unification in the MSSM

    CERN Document Server

    Raby, Stuart; Schmidt-Hoberg, Kai

    2009-01-01

    We discuss the issue of precision gauge unification in the MSSM. We find that a comparably light gluino, as it emerges in certain patterns of soft supersymmetry breaking, can be a key ingredient for ensuring precision gauge unification without relying on the presence of extra particles around the scale of grand unification. In particular, the so-called mirage pattern for gaugino masses can naturally lead to precision gauge unification. There is also an interesting correlation with reduced fine-tuning, due to rather light gluinos.

  18. Workshop on Precision Measurements of alphas

    CERN Document Server

    Bethke, S; Kluth, S; Schieck, J; Stewart, I W; Aoki, S; Beneke, M; Blumlein, J; Brambilla, N; Brodsky, S; Descotes-Genon, S; Erler, J; Forte, S; Gehrmann, T; Golterman, M; Hashimoto, S; Kronfeld, A; Kuhn, J; Lepage, P; Martin, A; Mateu, V; Menke, S; Nomura, Y; Pahl, C; Petriello, F; Pich, A; Rabbertz, K; Salam, G; Schulz, H; Sommer, R; Steinhauser, M; Webber, B; Yuan, CP; Zanderighi, G

    2011-01-01

    These are the proceedings of the "Workshop on Precision Measurements of alphas" held at the Max-Planck-Institute for Physics, Munich, February 9-11, 2011. The workshop explored in depth the determination of alphas(mZ) in the MS-bar scheme from the key categories where high precision measurements are currently being made, including DIS and global PDF fits, tau-decays, electroweak precision observables and Z-decays, event-shapes, and lattice QCD. These proceedings contain a short summary contribution from the speakers, as well as the lists of authors, conveners, participants, and talks.

  19. Precision spectroscopy of the helium atom

    Institute of Scientific and Technical Information of China (English)

    Shui-ming HU; Zheng-Tian LU; Zong-Chao YAN

    2009-01-01

    Persistent efforts in both theory and experiment have yielded increasingly precise understanding of the helium atom. Because of its simplicity, the helium atom has long been a testing ground for relativistic and quantum electrodynamic effects in few-body atomic systems theoretically and experimentally.Comparison between theory and experiment of the helium spectroscopy in ls2p3pJ can potentially extract a very precise value of the fine structure constant a. The helium atom can also be used to explore exotic nuclear structures. In this paper, we provide a brief review of the recent advances in precision calculations and measurements of the helium atom.

  20. Mixed-Precision Spectral Deferred Correction: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Grout, Ray W. S.

    2015-09-02

    Convergence of spectral deferred correction (SDC), where low-order time integration methods are used to construct higher-order methods through iterative refinement, can be accelerated in terms of computational effort by using mixed-precision methods. Using ideas from multi-level SDC (in turn based on FAS multigrid ideas), some of the SDC correction sweeps can use function values computed in reduced precision without adversely impacting the accuracy of the final solution. This is particularly beneficial for the performance of combustion solvers such as S3D [6] which require double precision accuracy but are performance limited by the cost of data motion.

  1. Developing and implementing a high precision setup system

    Science.gov (United States)

    Peng, Lee-Cheng

    The demand for high-precision radiotherapy (HPRT) was first implemented in stereotactic radiosurgery using a rigid, invasive stereotactic head frame. Fractionated stereotactic radiotherapy (SRT) with a frameless device was developed along a growing interest in sophisticated treatment with a tight margin and high-dose gradient. This dissertation establishes the complete management for HPRT in the process of frameless SRT, including image-guided localization, immobilization, and dose evaluation. The most ideal and precise positioning system can allow for ease of relocation, real-time patient movement assessment, high accuracy, and no additional dose in daily use. A new image-guided stereotactic positioning system (IGSPS), the Align RT3C 3D surface camera system (ART, VisionRT), which combines 3D surface images and uses a real-time tracking technique, was developed to ensure accurate positioning at the first place. The uncertainties of current optical tracking system, which causes patient discomfort due to additional bite plates using the dental impression technique and external markers, are found. The accuracy and feasibility of ART is validated by comparisons with the optical tracking and cone-beam computed tomography (CBCT) systems. Additionally, an effective daily quality assurance (QA) program for the linear accelerator and multiple IGSPSs is the most important factor to ensure system performance in daily use. Currently, systematic errors from the phantom variety and long measurement time caused by switching phantoms were discovered. We investigated the use of a commercially available daily QA device to improve the efficiency and thoroughness. Reasonable action level has been established by considering dosimetric relevance and clinic flow. As for intricate treatments, the effect of dose deviation caused by setup errors remains uncertain on tumor coverage and toxicity on OARs. The lack of adequate dosimetric simulations based on the true treatment coordinates from

  2. Megavoltage cone-beam CT-guided radiation therapy of nasopharyngeal carcinoma in the process of positioning precision%兆伏级锥形束CT引导的鼻咽癌放射治疗过程中的摆位精度分析

    Institute of Scientific and Technical Information of China (English)

    龚蔷; 傅深; 薛梅; 周丹; 徐文才

    2012-01-01

    目的:应用兆伏级锥形束CT分析鼻咽癌调强放射治疗过程中体重变化对摆位精度的影响.方法:15例行逆向调强治疗的鼻咽癌患者,利用三维激光摆位,每周进行体重测量和伏级锥形束CT扫描(采用8MU).采用smoothing H&N滤波核函数进行三维图像重建(矩阵256×256,层厚1mm).将重建的MV-CBCT图像与计划CT进行融合,记录等中心参考点在X、Y、Z坐标轴方向的摆位误差.在每次重建的MV-CBCT图像中都选择颅底和第1、3、5颈椎水平四个层面,测量四个层面的皮肤轮廓在身体左右方向(X轴)、头脚方向(Y轴)、前后方向(Z轴)的距离.以第1次扫描图像作为参考,计算每周皮肤轮廓缩小的距离,分析体重和皮肤轮廓缩小程度与摆位误差的关系.结果:15例患者在放疗过程中体重每周都有下降的趋势,至放疗结束,患者的体重平均下降4.5kg、其中最多消瘦15.2kg.不同层面皮肤轮廓之间的距离逐渐缩小,但第1颈椎和第3颈椎水平皮肤轮廓收缩最明显;颅底和第5颈椎层面的皮肤轮廓距离缩小相对较小.整个治疗过程中,等中心参考点在X、Y、Z坐标轴方向的平均摆位误差分别为0.15mm,0.28mm,0.21mm.随着体重的下降,X、Z轴方向的摆位误差轻微增加(P>0.05),但摆位误差均≤3mm;而Y轴方向的摆位误差明显增加(P<0.05),最大误差达到7mm.结论:鼻咽肿瘤患者放疗过程中,体重有逐渐下降的趋势,不同层面皮肤轮廓之间的距离逐渐缩小,其中第1和第3颈椎水平皮肤轮廓收缩最明显;体重下降对X、Z轴方向的摆位误差影响不明显,但对Y轴的影响较大.%Objective:To analyze the influence of weight change to the accuracy of the patient positioning in the intensive modulated radiotherapy (IMRT) of nasopharyngeal carcinoma with mega - volt cone beam CT ( MV -CBCT). Methods: Fifteen patients diagnosed as nasopharyngeal carcinoma were treated with inverse IMRT. With three

  3. Drug Abuse and the Brain: A Viewer's Guide.

    Science.gov (United States)

    CSR, Inc., Arlington, VA.

    This guide provides a detailed look at the biological basis of drug addiction, examining how the brain and its reward system work and how drug abuse can cause fundamental changes in the way the brain works. It is a resource for clinicians and practitioners. The first section of the guide provides an outline of the following basic concepts…

  4. The Experience of Living with and Using a Dog Guide.

    Science.gov (United States)

    Miner, Rachel Joy-Taub

    2001-01-01

    A study of eight adults who use dog guides found four themes that described the experience of using a dog guide: increased confidence, increased independence, changed public interactions, and additional responsibilities or inconveniences. Most participants described their dogs as social "ice breakers" that led to increased interaction with people.…

  5. 1997~2016年国际蹦床规则变化规律性导向特征研究%The study of the international trampoline rules change regularity guide features in 1997~2016

    Institute of Scientific and Technical Information of China (English)

    何茂贵; 韩华; 徐刚

    2015-01-01

    采用文献资料、专家访谈、分析归纳、数理统计法等方法,对1997~2016年五个奥运周期国际蹦床评分规则的变化规律性导向特征进行了分析与研究,结果发现:把握高、难、准、美蹦床运动发展的总方向,突出项目特点而不断引导运动员掌握不同类型的多种动作,坚持敦促运动员努力提高成套动作的完成难度和质量,持续鼓励运动员进行创新并顺应蹦床运动技术的时代发展而不断完善评分规则,使其不断地对蹦床运动的发展起到积极的促进、规范和导向作用,是主导当今世界蹦床评分规则修订变化的主要规律性特征;未来大赛第一套动作的发展将与第二套动作趋同,而相关的系列要求与新规定,还将会为迎合其方向的发展内容而修订。%By using the methods of literature,expert interviews,analysis induction and mathematical analysis,this paper studies the oriented features for the regularity of changes of international trampoline grading rules in the five Olympic periods during 1997 to 2016. The results show that grasping the general direction of high,difficult,quasi and beautiful for the trampoline development,in order to highlight the project features and continuing to guide the athletes to grasp various actions of different types, adhering to urge athletes trying to enhance the difficulty and quality to finish complete set movement,continuing to encourage athletes to innovation and adapting to the era development of trampoline technology and continuous improvement of score rules in order to make it play a positive,standards and guidance role for the development of trampoline sports.

  6. Good Practice Guides

    OpenAIRE

    Public Health Agency

    2010-01-01

    This series of Good Practice Guides is designed to share important information about health inequalities and some of the evidence-based measures that can be taken to reduce the stark differences in health and wellbeing within populations.

  7. EPA QUICK REFERENCE GUIDES

    Science.gov (United States)

    EPA Quick Reference Guides are compilations of information on chemical and biological terrorist agents. The information is presented in consistent format and includes agent characteristics, release scenarios, health and safety data, real-time field detection, effect levels, samp...

  8. Guide to Physical Activity

    Science.gov (United States)

    ... Families ( We Can! ) Health Professional Resources Guide to Physical Activity Physical activity is an important part of your ... to injury. Examples of moderate-intensity amounts of physical activity Common Chores Washing and waxing a car for ...

  9. Magnetic microscopy guide

    Directory of Open Access Journals (Sweden)

    Harald Brune

    2005-05-01

    Full Text Available Magnetic Microscopy of Nanostructures is an excellent introduction for newcomers and, for those working in the field, can be used as a guide before seeking more up-to-date literature, saysHarald Brune.

  10. EERE Peer Review Guide

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-01-18

    The primary purpose of this guide is to provide managers and staff guidance in establishing formal in-progress peer review that provides intellectually fair expert evaluation of EERE RD3 and supporting business administration programs, both retrospective and prospective.

  11. Guide to Insulating Sheathing

    Energy Technology Data Exchange (ETDEWEB)

    None

    2007-10-11

    This guide examines new methods of enclosure designs that provide high thermal performance and long-term durability but also take opportunities to reduce material use, simplify or integrate systems and details, and potentially reduce overall initial costs of construction.

  12. Ultrasound guided supraclavicular block.

    LENUS (Irish Health Repository)

    Hanumanthaiah, Deepak

    2013-09-01

    Ultrasound guided regional anaesthesia is becoming increasingly popular. The supraclavicular block has been transformed by ultrasound guidance into a potentially safe superficial block. We reviewed the techniques of performing supraclavicular block with special focus on ultrasound guidance.

  13. Magnetic microscopy guide

    OpenAIRE

    Harald Brune

    2005-01-01

    Magnetic Microscopy of Nanostructures is an excellent introduction for newcomers and, for those working in the field, can be used as a guide before seeking more up-to-date literature, saysHarald Brune.

  14. Buyers Guide for 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    This annual guide gives names and addresses of manufacturers worldwide equipment for drilling, blasting, tunnel boring, loading, haulage, support, concreting and grouting, tunnel furnishing and safety protection. Electrical, mechanical and geotechnical equipment are also included.

  15. Kenai Wilderness Management Guide

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Kenai Wilderness Management Guide is a description, interpretation, and synthesis of Congressional legislation, Department of the Interior regulation, and Fish...

  16. Precision Munition Electro-Sciences Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This facility allows the characterization of the electro-magnetic environment produced by a precision weapon in free flight. It can measure the radiofrequency (RF)...

  17. Toward precision medicine in neurological diseases.

    Science.gov (United States)

    Tan, Lin; Jiang, Teng; Tan, Lan; Yu, Jin-Tai

    2016-03-01

    Technological development has paved the way for accelerated genomic discovery and is bringing precision medicine into view. The goal of precision medicine is to deliver optimally targeted and timed interventions tailored to an individual's molecular drivers of disease. Neurological diseases are promisingly suited models for precision medicine because of the rapidly expanding genetic knowledge base, phenotypic classification, the development of biomarkers and the potential modifying treatments. Moving forward, it is crucial that through these integrated research platforms to provide analysis both for accurate personal genome analysis and gene and drug discovery. Here we describe our vision of how precision medicine can bring greater clarity to the clinical and biological complexity of neurological diseases. PMID:27127757

  18. Prospects for Precision Neutrino Cross Section Measurements

    Energy Technology Data Exchange (ETDEWEB)

    Harris, Deborah A. [Fermilab

    2016-01-28

    The need for precision cross section measurements is more urgent now than ever before, given the central role neutrino oscillation measurements play in the field of particle physics. The definition of precision is something worth considering, however. In order to build the best model for an oscillation experiment, cross section measurements should span a broad range of energies, neutrino interaction channels, and target nuclei. Precision might better be defined not in the final uncertainty associated with any one measurement but rather with the breadth of measurements that are available to constrain models. Current experience shows that models are better constrained by 10 measurements across different processes and energies with 10% uncertainties than by one measurement of one process on one nucleus with a 1% uncertainty. This article describes the current status of and future prospects for the field of precision cross section measurements considering the metric of how many processes, energies, and nuclei have been studied.

  19. Precision Farming Tools. Soil Electrical Conductivity

    OpenAIRE

    Grisso, Robert D. (Robert Dwight), 1956-; Alley, Mark M.; Holshouser, David Lee, 1963-; Thomason, Wade Everett

    2005-01-01

    Soil electrical conductivity (EC) is one of the simplest, least expensive soil measurements available to precision farmers today. Soil EC measurement can provide more measurements in a shorter amount of time than traditional grid soil sampling.

  20. Railo 3 Beginner's Guide

    CERN Document Server

    Drew, Mark

    2011-01-01

    Part of Packt's Beginner's Guide series, this book uses practical examples and screenshots to steadily guide the reader through setting up and using Railo. If you want to develop your own dynamic web applications using CFML, then this book is for you. No prior experience with Railo or CFML is required, although you will be expected to have some web application development experience and knowledge of HTML.

  1. Hand deburring guide

    Energy Technology Data Exchange (ETDEWEB)

    Gillespie, L.K.

    1979-07-01

    Appropriate hand deburring techniques have always been difficult to define because of the infinite variety of part shapes, sizes, materials, and burr conditions. This guide, however, has been prepared to assist those responsible for hand deburring. The purpose of the guide is to define Bendix Kansas City burr specifications and inspection practices; to define the results of practical tests on hand deburring; to define some typical in-house practices; and to define the in-house tools available for this work.

  2. Security guide for subcontractors

    Energy Technology Data Exchange (ETDEWEB)

    Adams, R.C.

    1991-01-01

    This security guide of the Department of Energy covers contractor and subcontractor access to DOE and Mound facilities. The topics of the security guide include responsibilities, physical barriers, personnel identification system, personnel and vehicular access controls, classified document control, protecting classified matter in use, storing classified matter repository combinations, violations, security education clearance terminations, security infractions, classified information nondisclosure agreement, personnel security clearances, visitor control, travel to communist-controlled or sensitive countries, shipment security, and surreptitious listening devices.

  3. Visual explorer facilitator's guide

    CERN Document Server

    Palus, Charles J

    2010-01-01

    Grounded in research and practice, the Visual Explorer™ Facilitator's Guide provides a method for supporting collaborative, creative conversations about complex issues through the power of images. The guide is available as a component in the Visual Explorer Facilitator's Letter-sized Set, Visual Explorer Facilitator's Post card-sized Set, Visual Explorer Playing Card-sized Set, and is also available as a stand-alone title for purchase to assist multiple tool users in an organization.

  4. Liferay Beginner's Guide

    CERN Document Server

    Chen, Robert; Bhatt, Samir

    2011-01-01

    Part of Packt's Beginner's Guide series, each chapter follows the creation of a fictional neighbourhood site to demonstrate an aspect of Liferay portal with practical examples, screenshots, and step-by-step instructions. All you need in order to benefit from the Liferay Beginner's Guide is programming experience. No prior knowledge of Liferay is required, although experienced Liferay portal programmers who need to get up to speed with its latest features will also find this book useful.

  5. VOLTTRON: User Guide

    Energy Technology Data Exchange (ETDEWEB)

    Lutes, Robert G.; Katipamula, Srinivas; Akyol, Bora A.; Tenney, Nathan D.; Haack, Jereme N.; Monson, Kyle E.; Carpenter, Brandon J.

    2014-04-24

    This document is a user guide for the deployment of the Transactional Network platform and agent/application development within the VOLTTRON. The intent of this user guide is to provide a description of the functionality of the Transactional Network Platform. This document describes how to deploy the platform, including installation, use, guidance, and limitations. It also describes how additional features can be added to enhance its current functionality.

  6. Wind Energy Teachers Guide

    Energy Technology Data Exchange (ETDEWEB)

    anon.

    2003-01-01

    This guide, created by the American Wind Association, with support from the U.S. Department of Energy, is a learning tool about wind energy targeted toward grades K-12. The guide provides teacher information, ideas for sparking children's and students' interest, suggestions for activities to undertake in and outside the classroom, and research tools for both teachers and students. Also included is an additional resources section.

  7. Single mode, extreme precision Doppler spectrographs

    OpenAIRE

    Schwab, Christian; Leon-Saval, Sergio G.; Betters, Christopher H.; Bland-Hawthorn, Joss; Mahadevan, Suvrath

    2012-01-01

    The 'holy grail' of exoplanet research today is the detection of an earth-like planet: a rocky planet in the habitable zone around a main-sequence star. Extremely precise Doppler spectroscopy is an indispensable tool to find and characterize earth-like planets; however, to find these planets around solar-type stars, we need nearly one order of magnitude better radial velocity (RV) precision than the best current spectrographs provide. Recent developments in astrophotonics (Bland-Hawthorn & Ho...

  8. Precise Asymptotics for Lévy Processes

    Institute of Scientific and Technical Information of China (English)

    Zhi Shui HU; Chun SU

    2007-01-01

    Let {X(t), t ≥ 0} be a Lévy process with EX(1)=0 and EX2(1)<∞. In this paper, we shall give two precise asymptotic theorems for {X(t), t≥0}. By the way, we prove the corresponding conclusions for strictly stable processes and a general precise asymptotic proposition for sums of i.i.d.random variables.

  9. High precision machining on high speed machines

    OpenAIRE

    J. Kopač

    2007-01-01

    Purpose: Modern Machines for precision products for three dimensional machining have by milling over 20.000 rpm. Differences between hard and soft machining have influences on concept of machines. Stiffness and rigidity are characteristics and variables which caused the precision and quality of machined part.Design/methodology/approach: This paper introduce some of interesting modern machine tools with different concept as DCG (Drive in Centre of Gravity - Mori Seiki), LAF (Look Ahead Functio...

  10. Precision siting of a particle accelerator

    International Nuclear Information System (INIS)

    Precise location is a specific survey job that involves a high skilled work to avoid unrecoverable results at the project installation. As a function of the different process stages, different specifications can be applied, invoking different instruments: theodolite, measurement tape, distanciometer, invar wire. This paper, based on experience obtained at the installation of particle accelerator equipment, deals with general principles of precise location: tolerance definitions, increasing accuracy techniques, schedule of locations, sensitivity analysis, quality control methods. (author)

  11. Precise subtyping for synchronous multiparty sessions

    OpenAIRE

    Dezani-Ciancaglini, Mariangiola; Ghilezan, Silvia; Jakšić, Svetlana; Pantović, Jovanka; Yoshida, Nobuko

    2016-01-01

    The notion of subtyping has gained an important role both in theoretical and applicative domains: in lambda and concurrent calculi as well as in programming languages. The soundness and the completeness, together referred to as the preciseness of subtyping, can be considered from two different points of view: operational and denotational. The former preciseness has been recently developed with respect to type safety, i.e. the safe replacement of a term of a smaller type when a term of a bigge...

  12. High precision inter-continental GPS network

    OpenAIRE

    Monico, João Francisco Galera

    1995-01-01

    GPS relative positioning provides precision of the order of 1 part per million (ppm) within relatively short periods of time. Considering this level of precision, together with the fact that the cost of GPS receivers is continuing come down, it is now apparent that most of the future geodetic surveys will be performed by GPS, It is therefore important to establish geodetic control networks which are suitable for geodetic GPS activities. The Brazilian Institute of Geography and Statistics (IBG...

  13. Macromodel of Precise Signal-Phase Meter

    OpenAIRE

    Matej Šalamon; Bojan Jarc

    2012-01-01

    This paper presents a precise macromodel of a signal-phase meter, which allows continuous phase measurement during simulation. It has been developed as a support tool during the design process of a signal-conditioning circuit for incremental position encoders. The development of a signal conditioning circuit requires precise measurements of small signal phases, amplitudes and offsets using the analog/digital circuit simulator. The phase measurement cannot be performed directly with a simulato...

  14. RISK MANAGEMENT POTENTIAL OF PRECISION FARMING TECHNOLOGIES

    OpenAIRE

    Lowenberg-DeBoer, James

    1999-01-01

    Initial ideas on risk management uses of precision agricultural technology focused on site-specific treatment of problem areas to reduce the probability of low yields and returns. Recent discussions deal with sensor and remote-sensing information to improve marketing and "as applied maps" as trace-back mechanisms to manage liability. A theoretical model is presented that suggests that there are plausible circumstances under which precision farming can reduce temporal yield variability. Empiri...

  15. Improved Precision Measurement of the Casimir Force

    OpenAIRE

    Roy, Anushree; Lin, Chiung-Yuan; Mohideen, U.

    1999-01-01

    We report an improved precision measurement of the Casimir force. The force is measured between a large Al coated sphere and flat plate using an Atomic Force Microscope. The primary experimental improvements include the use of smoother metal coatings, reduced noise, lower systematic errors and independent measurement of surface separations. Also the complete dielectric spectrum of the metal is used in the theory. The average statistical precision remains at the same 1% of the forces measured ...

  16. DECISION SUPPORT SYSTEM FOR PRECISION FARMING

    OpenAIRE

    Harmandeep Singh; Nitika Sharma

    2013-01-01

    A decision support system for precision farming is designed to assist farmers, agricultural experts, research workers or any intellectuals with guidance in making various farming related decisions and help them to access, display and analyze data that have geographic content and meaning. The concept of precision farming is not only related with the use of technologies but it is also about the five R’s that is use of right input (nutrients, water, fertilizer, money, machinery etc.), at the rig...

  17. Data Mining und Wissensentdeckung im Precision Farming

    OpenAIRE

    Weigert, Georg

    2006-01-01

    Als ein Hemmnis für die Akzeptanz von Precision Farming können Wissensdefizite identifiziert werden. Es existieren bis dato nur wenige Algorithmen zur Umsetzung einer teilflächenspezifischen Bewirtschaftung, die überlegene ökonomische Ergebnisse erwarten lassen. Im Rahmen dieser Arbeit wird die Methode “Wissensentdeckung in Datenbanken” eingesetzt, um ökonomisch optimierte Entscheidungsregeln zu erzeugen. Dazu werden die einzelnen Prozessschritte dieser Methode für den Bereich Precision Farmi...

  18. Precision Nitrogen Fertilization Technology with Micro Grids

    OpenAIRE

    Biermacher, Jon T.; Epplin, Francis M.; Brorsen, B. Wade; Solie, John B.; Raun, Bill

    2006-01-01

    Sensor-based precision fertilizer technologies are being developed and researched by production scientists. One such technology uses normalized difference vegetation index (NDVI) reflectance measurements of growing winter wheat plants and a nitrogen fertilizer optimization algorithm (NFOA) to determine nitrogen requirement necessary for plants to reach their yield plateau. A number of precision fertilizer application systems that use this technology are considered in this paper. A linear resp...

  19. Electroweak Precision Data and New Gauge Bosons

    OpenAIRE

    Erler, Jens

    2009-01-01

    I review constraints on the Standard Model (SM) Higgs boson from high energy electroweak (EW) precision data. The same data set also strongly limits various mixing effects of hypothetical extra neutral gauge bosons (Z') with the ordinary Z. I also discuss low energy precision measurements which are sensitive to other aspects of Z' physics, such as the direct exchange amplitude and the flavor or CP violating sectors.

  20. Precision optical displacement measurements using biphotons

    OpenAIRE

    Lyons, Kevin; Pang, Shengshi; Kwiat, Paul G.; Jordan, Andrew N

    2016-01-01

    We propose and examine the use of biphoton pairs, such as those created in parametric down conversion or four-wave mixing, to enhance the precision and the resolution of measuring optical displacements by position-sensitive detection. We show that the precision of measuring a small optical beam displacement with this method can be significantly enhanced by the correlation between the two photons, given the same optical mode. The improvement is largest if the correlations between the photons a...

  1. NONEL High Precision MS Delay Detonator

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The NONEL high precision MS Delay Detonator (FDG-1detonator) is introduced. The main aspects about the FDG-1 detonator include the choice of structure, delay composition, control of the gas chamber, o ptimum charge and density, suitable explosives per meter in the NONEL tube, base firing charge and the main specifications. The improvement of the characteristics of FDG-1 detonator has been tested systematical ly. The testing method is reliable and its precision can meet the dema nd for usage.

  2. Modernising the CERN Admin e-guide

    CERN Multimedia

    DG-RPC-PA (section des processus administratifs)

    2014-01-01

    In just a few years, the CERN Admin e-guide has become the essential guide for CERN's administrative procedures, intended not just for administrative services but for all members of the personnel of CERN. The guide is edited by the Administrative Process Section (DG-RPC-PA) and allows users to look up administrative procedures and forms relating to the application of the Staff Rules and Regulations easily in both French and English. Site visit statistics show that 5000 people on average consult the Admin e-guide each month. The most consulted procedures are those relating to green licence plates, taxes, Swiss and French cards and leave. The site has just been moved over to Drupal, which will make it easier to update the information provided and will improve content management. This system change meant migrating 220 procedures and more than 500 frequently asked questions. The structure has been revised for clarity, but the principles that made the guide so successful have not changed, namely the e...

  3. Radiological design guide

    International Nuclear Information System (INIS)

    The purpose of this design guide is to provide radiological safety requirements, standards, and information necessary for designing facilities that will operate without unacceptable risk to personnel, the public, or the environment as required by the US Department of Energy (DOE). This design guide, together with WHC-CM-4-29, Nuclear Criticality Safety, WHC-CM-4-46, Nonreactor Facility Safety Analysis, and WHC-CM-7-5, Environmental Compliance, covers the radiation safety design requirements at Westinghouse Hanford Company (WHC). This design guide applies to the design of all new facilities. The WHC organization with line responsibility for design shall determine to what extent this design guide shall apply to the modifications to existing facilities. In making this determination, consideration shall include a cost versus benefit study. Specifically, facilities that store, handle, or process radioactive materials will be covered. This design guide replaces WHC-CM-4-9 and is designated a living document. This design guide is intended for design purposes only. Design criteria are different from operational criteria and often more stringent. Criteria that might be acceptable for operations might not be adequate for design

  4. Radiological design guide

    Energy Technology Data Exchange (ETDEWEB)

    Evans, R.A.

    1994-08-16

    The purpose of this design guide is to provide radiological safety requirements, standards, and information necessary for designing facilities that will operate without unacceptable risk to personnel, the public, or the environment as required by the US Department of Energy (DOE). This design guide, together with WHC-CM-4-29, Nuclear Criticality Safety, WHC-CM-4-46, Nonreactor Facility Safety Analysis, and WHC-CM-7-5, Environmental Compliance, covers the radiation safety design requirements at Westinghouse Hanford Company (WHC). This design guide applies to the design of all new facilities. The WHC organization with line responsibility for design shall determine to what extent this design guide shall apply to the modifications to existing facilities. In making this determination, consideration shall include a cost versus benefit study. Specifically, facilities that store, handle, or process radioactive materials will be covered. This design guide replaces WHC-CM-4-9 and is designated a living document. This design guide is intended for design purposes only. Design criteria are different from operational criteria and often more stringent. Criteria that might be acceptable for operations might not be adequate for design.

  5. Control system design guide

    Energy Technology Data Exchange (ETDEWEB)

    Sellers, David; Friedman, Hannah; Haasl, Tudi; Bourassa, Norman; Piette, Mary Ann

    2003-05-01

    The ''Control System Design Guide'' (Design Guide) provides methods and recommendations for the control system design process and control point selection and installation. Control systems are often the most problematic system in a building. A good design process that takes into account maintenance, operation, and commissioning can lead to a smoothly operating and efficient building. To this end, the Design Guide provides a toolbox of templates for improving control system design and specification. HVAC designers are the primary audience for the Design Guide. The control design process it presents will help produce well-designed control systems that achieve efficient and robust operation. The spreadsheet examples for control valve schedules, damper schedules, and points lists can streamline the use of the control system design concepts set forth in the Design Guide by providing convenient starting points from which designers can build. Although each reader brings their own unique questions to the text, the Design Guide contains information that designers, commissioning providers, operators, and owners will find useful.

  6. Prehistory: A Teacher's Guide. Education on Site.

    Science.gov (United States)

    Corbishley, Mike; Darvill, Tim; Stone, Peter

    Chronologically prehistory accounts for over 99% of the human past. During this time, the earliest human ancestors spread across the world from Africa and changed, modified, and evolved until the species "Homo sapiens sapiens" made its appearance some 200,000 years ago. This teacher's guide provides an outline of the prehistory of the British…

  7. A Citizen's guide to climate refugees

    International Nuclear Information System (INIS)

    Friends of the Earth Australia is commemorating World Refugee Day in 2005 by publishing a 'Citizens Guide to Climate Refugees'. This publication gives the basic facts on climate change, greenhouse gas emissions; why people could become climate refugees, how many and where are they likely to come from; and what can be done about it

  8. REEF MANAGER'S GUIDE TO CORAL BLEACHING

    Science.gov (United States)

    A Reef Manager's Guide to Coral Bleaching is the result of a collaborative effort by over 50 scientists and managers to: (1) engage in information-sharing in the areas of coral reef science and management for climate change and coral bleaching; and (2) compile a management tool ...

  9. Social Marketing. A Guide. First Draft.

    Science.gov (United States)

    Rosenau, Fred S.

    This introductory guide to nonprofit social marketing provides marketing techniques and guidelines in seven chapters. Topics covered include a general discussion of social marketing, with several definitions; market research, including factors to be considered in planning a marketing strategy, forces for and against educational changes, cluster…

  10. An attempt for the precise isotope analysis

    International Nuclear Information System (INIS)

    A compact virtual image double focusing mass spectrometer was adopted for the precise isotope analysis with surface ionization ion source. A interface with 16-bit DA converter was set into the computer for automatic control of magnetic field. This new system enabled to measure isotopic ratios by peak hopping method. To obtain high precision, the digital voltmeter under computer control was introduced for collecting data and processing them successively. The flatness of the peak top and the stability of the magnetic field during the single run were checked and found to be satisfactory. For the test of the measuring system, the isotopic ratios of K, Rb and Sr were measured using shelf reagents. It was concluded that (1) by the Faraday collector, the isotopic ratio could be measured with the precision better than 0.01 % when the ion currents for both isotopes were higher than 10-11 A, (2) for the isotope less abundant than 10-4, the precision achieved a few percent by Faraday collector with ion current of 10-15 A, while the precision was within 1 % by SEM collector with ion current of 10-17 A. The performance of the mass spectrometer was found to be satisfactory to measure isotopic ratios with a high precision. (author)

  11. Precision validation of MIPAS-Envisat products

    Directory of Open Access Journals (Sweden)

    C. Piccolo

    2007-01-01

    Full Text Available This paper discusses the variation and validation of the precision, or estimated random error, associated with the ESA Level 2 products from the Michelson Interferometer for Passive Atmospheric Sounding (MIPAS. This quantity represents the propagation of the radiometric noise from the spectra through the retrieval process into the Level 2 profile values. The noise itself varies with time, steadily rising between ice decontamination events, but the Level 2 precision has a greater variation due to the atmospheric temperature which controls the total radiance received. Hence, for all species, the precision varies latitudinally/seasonally with temperature, with a small superimposed temporal structure determined by the degree of ice contamination on the detectors. The precision validation involves comparing two MIPAS retrievals at the intersections of ascending/descending orbits. For 5 days per month of full resolution MIPAS operation, the standard deviation of the matching profile pairs is computed and compared with the precision given in the MIPAS Level 2 data, except for NO2 since it has a large diurnal variation between ascending/descending intersections. Even taking into account the propagation of the pressure-temperature retrieval errors into the VMR retrieval, the standard deviation of the matching pairs is usually a factor 1–2 larger than the precision. This is thought to be due to effects such as horizontal inhomogeneity of the atmosphere and instability of the retrieval.

  12. Secret World of the Forbidden City: Splendors from Imperial China, 1644-1911 and Change and Continuity: Chinese Americans in California. Exhibition Information and Curriculum Guide for Teachers Grades 2-11.

    Science.gov (United States)

    2000

    The materials in this curriculum guide were designed to prepare teachers and students in grades 2-11 for the "Secret World of the Forbidden City: Splendors from China's Imperial Palace 1644-1911" exhibition at the Oakland Museum of California Education Department, to inform teachers and students about Imperial China, and to illuminate the…

  13. Guided ionization waves: Theory and experiments

    International Nuclear Information System (INIS)

    This review focuses on one of the fundamental phenomena that occur upon application of sufficiently strong electric fields to gases, namely the formation and propagation of ionization waves–streamers. The dynamics of streamers is controlled by strongly nonlinear coupling, in localized streamer tip regions, between enhanced (due to charge separation) electric field and ionization and transport of charged species in the enhanced field. Streamers appear in nature (as initial stages of sparks and lightning, as huge structures—sprites above thunderclouds), and are also found in numerous technological applications of electrical discharges. Here we discuss the fundamental physics of the guided streamer-like structures—plasma bullets which are produced in cold atmospheric-pressure plasma jets. Plasma bullets are guided ionization waves moving in a thin column of a jet of plasma forming gases (e.g., He or Ar) expanding into ambient air. In contrast to streamers in a free (unbounded) space that propagate in a stochastic manner and often branch, guided ionization waves are repetitive and highly-reproducible and propagate along the same path—the jet axis. This property of guided streamers, in comparison with streamers in a free space, enables many advanced time-resolved experimental studies of ionization waves with nanosecond precision. In particular, experimental studies on manipulation of streamers by external electric fields and streamer interactions are critically examined. This review also introduces the basic theories and recent advances on the experimental and computational studies of guided streamers, in particular related to the propagation dynamics of ionization waves and the various parameters of relevance to plasma streamers. This knowledge is very useful to optimize the efficacy of applications of plasma streamer discharges in various fields ranging from health care and medicine to materials science and nanotechnology

  14. Guided exploration in virtual environments

    Science.gov (United States)

    Beckhaus, Steffi; Eckel, Gerhard; Strothotte, Thomas

    2001-06-01

    We describe an application supporting alternating interaction and animation for the purpose of exploration in a surround- screen projection-based virtual reality system. The exploration of an environment is a highly interactive and dynamic process in which the presentation of objects of interest can give the user guidance while exploring the scene. Previous systems for automatic presentation of models or scenes need either cinematographic rules, direct human interaction, framesets or precalculation (e.g. precalculation of paths to a predefined goal). We report on the development of a system that can deal with rapidly changing user interest in objects of a scene or model as well as with dynamic models and changes of the camera position introduced interactively by the user. It is implemented as a potential-field based camera data generating system. In this paper we describe the implementation of our approach in a virtual art museum on the CyberStage, our surround-screen projection-based stereoscopic display. The paradigm of guided exploration is introduced describing the freedom of the user to explore the museum autonomously. At the same time, if requested by the user, guided exploration provides just-in-time navigational support. The user controls this support by specifying the current field of interest in high-level search criteria. We also present an informal user study evaluating this approach.

  15. Precision Analysis of Three Dimension Free Curves Nanofabrication

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Three dimension free curves find wide applications in engineering. There is no problem to express them exactly mathematically, but th e reportage has not been done on the investigation of precision analysis of thre e-dimension free curves nanofabrication. Nanofabrication Precision includes the geometrical precision and the precision of driving system (below simply cal led the system precision). This paper submits the precision analysis method of c urve normal vector to analyze geometrical precision. ...

  16. Improvements in the Precise Measurement of Gamma Activity

    International Nuclear Information System (INIS)

    The precise measurement of the gamma radioactivity of sources in solid or liquid form has been significantly improved by two developments described in this paper. In one case the total gamma radiation from a highly active solid source, containing as much as 10mCi of a radioactive substance, is measured with a relative standard deviation of 0.03%. This is done by integrating the current from 4π scintillation detector during a 10-second measurement interval, thus generating a voltage which is recorded to five significant digits. The difficulties usually encountered with pulse-counting techniques of intensely active sources are eliminated, and the advantage is gained of having the precision related to the detection of a signal from 1010 events. Two prototype instruments have been constructed, each consisting of a detector, operational amplifier, digital voltmeter and crystal-controlled timer. They are capable of measuring the gamma activity of specimens slightly more than 1 m in length and nearly 4 cm in diameter. This significant improvement in the precise measurement of large quantities of radioactivity should find wide application in many fields. In the second case, the precise measurement of gamma activity is applied to liquid samples. Essential to the success of the method is the use of ageometry which is absolutely constant, and which eliminates the need for a measurement of the source volume. These aims are achieved by inserting a tall, cylindrical, flat-bottomed container into a well-type detector, and filling it with the radioactive solution until the top of the liquid is effectively at an 'infinite' distance from the detector. Additional amounts of the radioactive solution do not change the observed count rate. Other factors necessary for the attainment of high precision are the use of precise counting standards, self-absorption corrections for the radioactive element, and the specification of other solute concentrations in the solution. This technique

  17. A passion for precision - from the ultrafast to the ultraslow

    International Nuclear Information System (INIS)

    Full text: Femtosecond laser optical frequency comb synthesizers have become the established tool for measuring the frequency of light with extreme precision. By permitting phase-coherent comparisons of optical and microwave frequencies, they can serve as the clockwork for ultraprecise optical atomic clocks. Applications to laser spectroscopy of atomic hydrogen permit stringent tests of basic laws of quantum physics. Such experiments can yield accurate values of fundamental constants, and they may reveal slow changes of fundamental constants with the evolution of the universe. Laser frequency comb techniques can also control the light phase of femtosecond laser pulses, thus advancing the frontier of ultrafast science from the femtosecond to the attosecond regime. High harmonic generation with intense femtosecond pulses may extend frequency comb techniques to the extreme ultraviolet and soft x-ray regime, conquering new territory for precision laser spectroscopy and fundamental measurements. (author)

  18. Ultrasound-guided interventions of the foot and ankle.

    Science.gov (United States)

    Yablon, Corrie M

    2013-02-01

    Ultrasound (US) provides excellent delineation of tendons and ligaments in the foot and ankle and provides real-time visualization of a needle during interventions, yielding greater accuracy and efficacy than the traditional blind approach using anatomical landmarks. For this reason, US is rapidly gaining acceptance as the preferred modality for guiding interventions in the foot and ankle where the anatomy is complex, neurovascular structures should be identified, and precise technique is demanded. In the foot and ankle, US is especially useful to guide tendon sheath, bursal, and Achilles paratenon injections, Morton neuroma injections, plantar fascial injections, and joint aspirations and injections. PMID:23487336

  19. Neutron guides and scientific neutron equipment at CILAS/GMI

    International Nuclear Information System (INIS)

    CILAS company is the world's leading supplier of complete neutron guides systems. The neutron optics with multilayer coatings produced by CILAS have become an international standard for neutron beam transportation in the modern research institutes. During the last 30 years, CILAS designed, produced and installed more than 5000 meters of guides in many European, American and Asian countries. To reinforce its leadership and presence in neutron research, CILAS acquired the company Grenoble Modular Instruments (GMI), a leading company in high precision mechanics, engineering and manufacturing of spectrometers and scientific equipment for neutron and synchrotron research. (author)

  20. Principles and techniques for designing precision machines

    Energy Technology Data Exchange (ETDEWEB)

    Hale, L C

    1999-02-01

    This thesis is written to advance the reader's knowledge of precision-engineering principles and their application to designing machines that achieve both sufficient precision and minimum cost. It provides the concepts and tools necessary for the engineer to create new precision machine designs. Four case studies demonstrate the principles and showcase approaches and solutions to specific problems that generally have wider applications. These come from projects at the Lawrence Livermore National Laboratory in which the author participated: the Large Optics Diamond Turning Machine, Accuracy Enhancement of High- Productivity Machine Tools, the National Ignition Facility, and Extreme Ultraviolet Lithography. Although broad in scope, the topics go into sufficient depth to be useful to practicing precision engineers and often fulfill more academic ambitions. The thesis begins with a chapter that presents significant principles and fundamental knowledge from the Precision Engineering literature. Following this is a chapter that presents engineering design techniques that are general and not specific to precision machines. All subsequent chapters cover specific aspects of precision machine design. The first of these is Structural Design, guidelines and analysis techniques for achieving independently stiff machine structures. The next chapter addresses dynamic stiffness by presenting several techniques for Deterministic Damping, damping designs that can be analyzed and optimized with predictive results. Several chapters present a main thrust of the thesis, Exact-Constraint Design. A main contribution is a generalized modeling approach developed through the course of creating several unique designs. The final chapter is the primary case study of the thesis, the Conceptual Design of a Horizontal Machining Center.