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Sample records for central pattern generator

  1. Analog electronic model of the lobster pyloric central pattern generator

    International Nuclear Information System (INIS)

    An electronic circuit intended to simulate the nonlinear dynamics of a simplified 3-cell model of the pyloric central pattern generator in California spiny lobster stomato gastric ganglion is presented. The model employs the synaptic phase locked loop (SPLL) concept where the frequency of oscillations of a postsynaptic cell is mainly controlled by the synaptic current which depends on the phase shift between the oscillations. The theoretical study showed that the system has a stable steady state with correct phase shifts between the oscillations and that this regime is stable when the frequency of the pacemaker cell is varied over a wide range. The main bifurcations in the system were studied analytically, in computer simulations, and in experiments with the electronic circuit. The experimental measurements are in good agreement with the expectations of the theoretical model

  2. Topology of Central Pattern Generators Selection by Chaotic Neurons

    CERN Document Server

    Huerta, R; Rabinovich, M I; Abarbanel, Henry D I; Abarbanel, Henry D I

    1999-01-01

    Central Pattern Generators (CPGs) in invertebrates are comprised of networks of neurons in which every neuron has reciprocal connections to other members of the CPG. This is a ``closed'' network topology. An ``open'' topology, where one or more neurons receives input but does not send output to other member neurons, is not found in these CPGs. In this paper we investigate a possible reason for this topological structure using the ability to perform a biological functional task as a measure of the efficacy of the network. When the CPG is composed of model neurons which exhibit regular membrane voltage oscillations, open topologies are essentially as able to maximize this functionality as closed topologies. When we replace these models by neurons which exhibit chaotic membrane voltage oscillations, the functional criterion selects closed topologies when the demands of the task are increased, and these are the topologies observed in known CPG networks. As isolated neurons from invertebrate CPGs are known in some...

  3. Sexually differentiated central pattern generators in Xenopus laevis.

    Science.gov (United States)

    Zornik, Erik; Yamaguchi, Ayako

    2008-06-01

    Understanding the neural mechanisms that underlie the function of central pattern generators (CPGs) presents a formidable challenge requiring sophisticated tools and well-chosen model systems. In this article, we describe recent work on vocalizations of the African clawed frog Xenopus laevis. These behaviors are driven by sexually differentiated CPGs and are exceptionally well suited to this objective. In particular, a simplified mechanism of vocal production (independent of respiratory musculature) allows straightforward interpretations of nerve activity with respect to behavior. Furthermore, the development of a fictively vocalizing isolated brain, together with the finding of rapid androgen-induced masculinization of female vocalizations, provides an invaluable tool for determining how new behaviors arise from existing circuits. PMID:18471902

  4. Central Pattern Generation and the Motor Infrastructure for Suck, Respiration, and Speech

    Science.gov (United States)

    Barlow, Steven M.; Estep, Meredith

    2006-01-01

    The objective of the current report is to review experimental findings on centrally patterned movements and sensory and descending modulation of central pattern generators (CPGs) in a variety of animal and human models. Special emphasis is directed toward speech production muscle systems, including the chest wall and orofacial complex during…

  5. Xenopus Vocalizations Are Controlled by a Sexually Differentiated Hindbrain Central Pattern Generator

    OpenAIRE

    Rhodes, Heather J.; Yu, Heather J.; YAMAGUCHI, ayako

    2007-01-01

    Male and female African clawed frogs (Xenopus laevis) produce rhythmic, sexually distinct vocalizations as part of courtship and mating. We found that Xenopus vocal behavior is governed by a sexually dimorphic central pattern generator (CPG) and that fictive vocalizations can be elicited from an in vitro brain preparation by application of serotonin or by electrical stimulation of a premotor nucleus. Male brains produced fictive vocal patterns representing two calls commonly produced by males...

  6. Design of a central pattern generator using reservoir computing for learning human motion

    OpenAIRE

    Wyffels, Francis; Schrauwen, Benjamin

    2009-01-01

    To generate coordinated periodic movements, robot locomotion demands mechanisms which are able to learn and produce stable rhythmic motion in a controllable way. Because systems based on biological central pattern generators (CPGs) can cope with these demands, these kind of systems are gaining in success. In this work we introduce a novel methodology that uses the dynamics of a randomly connected recurrent neural network for the design of CPGs. When a randomly connected recurrent neural netwo...

  7. Setting the Pace: New Insights into Central Pattern Generator Interactions in Box Jellyfish Swimming

    OpenAIRE

    Stöckl, Anna Lisa; Petie, Ronald; Nilsson, Dan-Eric

    2011-01-01

    Central Pattern Generators (CPGs) produce rhythmic behaviour across all animal phyla. Cnidarians, which have a radially symmetric nervous system and pacemaker centres in multiples of four, provide an interesting comparison to bilaterian animals for studying the coordination between CPGs. The box jellyfish Tripedalia cystophora is remarkable among cnidarians due to its most elaborate visual system. Together with their ability to actively swim and steer, they use their visual system for multipl...

  8. From Spinal Central Pattern Generators to Cortical Network: Integrated BCI for Walking Rehabilitation

    Directory of Open Access Journals (Sweden)

    G. Cheron

    2012-01-01

    Full Text Available Success in locomotor rehabilitation programs can be improved with the use of brain-computer interfaces (BCIs. Although a wealth of research has demonstrated that locomotion is largely controlled by spinal mechanisms, the brain is of utmost importance in monitoring locomotor patterns and therefore contains information regarding central pattern generation functioning. In addition, there is also a tight coordination between the upper and lower limbs, which can also be useful in controlling locomotion. The current paper critically investigates different approaches that are applicable to this field: the use of electroencephalogram (EEG, upper limb electromyogram (EMG, or a hybrid of the two neurophysiological signals to control assistive exoskeletons used in locomotion based on programmable central pattern generators (PCPGs or dynamic recurrent neural networks (DRNNs. Plantar surface tactile stimulation devices combined with virtual reality may provide the sensation of walking while in a supine position for use of training brain signals generated during locomotion. These methods may exploit mechanisms of brain plasticity and assist in the neurorehabilitation of gait in a variety of clinical conditions, including stroke, spinal trauma, multiple sclerosis, and cerebral palsy.

  9. Global stability of synchronous and out-of-phase oscillations in central pattern generators

    CERN Document Server

    Landsman, A S

    2010-01-01

    Coupled arrays of Andronov-Hopf oscillators are investigated. These arrays can be diffusively or repulsively coupled, and can serve as central pattern generator models in animal locomotion and robotics. It is shown that repulsive coupling generates out-of-phase oscillations, while diffusive coupling generates synchronous oscillations. Specifically, symmetric solutions and their corresponding amplitudes are derived, and contraction analysis is used to prove global stability and convergence of oscillations to either symmetric out-of-phase or synchronous states, depending on the coupling constant. Next, the two mechanisms are used jointly by coupling multiple arrays. The resulting dynamics is analyzed, in a model inspired by the CPG-motorneuron network that controls the heartbeat of a medicinal leech.

  10. Afferent control of central pattern generators: experimental analysis of scratching in the decerebrate cat.

    Science.gov (United States)

    Baev, K V; Esipenko, V B; Shimansky, Y P

    1991-01-01

    depolarization is a result of affecting the depolarization generating system by this inner "sensory" activity. It is the model, with the aid of which the generator can work after deafferentation. The functional organization of a central pattern generator is considered. PMID:2052152

  11. Coupled chaotic oscillators and their relation to a central pattern generator for artificial quadrupeds

    Indian Academy of Sciences (India)

    Horacio Castellini; Efta Yudiarsah; Lilia Romanelli; Hilda A Cerdeira

    2005-04-01

    Animal locomotion employs different periodic patterns known as animal gaits. In 1993, Collins and Stewart recognized that gaits possessed certain symmetries and characterized the gaits of quadrupeds and bipeds using permutation symmetry groups, which impose constraints on the locomotion center called the central pattern generator (CPG) in the animal brain. They modeled the CPG by coupling four nonlinear oscillators and found that it was possible to reproduce all symmetries of the gaits by changing the coupling strength. Here we propose to extend this idea using coupled chaotic oscillators synchronized using the Pyragas method in order to characterize the CPG symmetries. We also evaluate the time series behavior when the foot is in contact with the ground: this has potential robotic applications.

  12. Bio-inspired Optimal Locomotion Reconfigurability of Quadruped Rovers using Central Pattern Generators

    Science.gov (United States)

    Bohra, Murtaza

    Legged rovers are often considered as viable solutions for traversing unknown terrain. This work addresses the optimal locomotion reconfigurability of quadruped rovers, which consists of obtaining optimal locomotion modes, and transitioning between them. A 2D sagittal plane rover model is considered based on a domestic cat. Using a Genetic Algorithm, the gait, pose and control variables that minimize torque or maximize speed are found separately. The optimization approach takes into account the elimination of leg impact, while considering the entire variable spectrum. The optimal solutions are consistent with other works on gait optimization, and are similar to gaits found in quadruped animals as well. An online model-free gait planning framework is also implemented, that is based on Central Pattern Generators is implemented. It is used to generate joint and control trajectories for any arbitrarily varying speed profile, and shown to regulate locomotion transition and speed modulation, both endogenously and continuously.

  13. Afferent control of central pattern generators: experimental analysis of locomotion in the decerebrate cat.

    Science.gov (United States)

    Baev, K V; Esipenko, V B; Shimansky YuP

    1991-01-01

    Changes in the motor activity of the spinal locomotor generator evoked by tonic and phasic peripheral afferent signals during fictitious locomotion of both slow and fast rhythms were analysed in the cat. The tonic afferent inflow was conditioned by the position of the hindlimb. The phasic afferent signals were imitated by electrical stimulation of hindlimb nerves. The correlation between the kinematics of hindlimb locomotor movement and sensory inflow was investigated during actual locomotion. Reliable correlations between motor activity parameters during fictitious locomotion were revealed in cases of both slow and fast "locomotor" rhythms. The main difference between these cases was that correlations "duration-intensity" were positive in the first and negative in the second case. The functional role of "locomotor" pattern dependence on tonic sensory inflow consisted of providing stability for planting the hindlimb on the ground. For any investigated afferent input the phase moments in the "locomotor" cycle were found, in which an afferent signal caused no rearrangement in locomotor generator activity. These moments corresponded to the transitions between "flexion" and "extension" phases and to the bursts of integral afferent activity observed during real locomotion. The data obtained are compared with the results previously described for the scratching generator. The character of changes in "locomotor" activity in response to tonic and phasic sensory signals was similar to that of such changes in "scratching" rhythm in the case of fast "locomotion". Intensification of the "flexion" phase caused by phasic high-intensity stimulation of cutaneous afferents during low "locomotor" rhythm was changed to inhibition (such as observed during "scratching") when this rhythm was fast. It is concluded that the main regularities of peripheral afferent control for both the locomotor and scratching generators are the same. Moreover, these central pattern generators are just

  14. Reticular activating system of a central pattern generator: premovement electrical potentials.

    Science.gov (United States)

    Tapia, Jesus A; Trejo, Argelia; Linares, Pablo; Alva, J Manuel; Kristeva, Rumyana; Manjarrez, Elias

    2013-10-01

    For the first time, here we characterize a bulbar reticular activating system (RAS) of neurons in decerebrate, deafferented and decerebellated cats producing a premovement electrical potential that we named obex slow potential (OSP). The OSP occurs about 0.8 ± 0.4 sec prior to the onset of a fictive-scratching-episode. Here, we describe two classes of bulbar neurons, off-on, which are silent but exhibit a 80 ± 56 Hz firing discharge at the beginning of (and during) the OSP, and on-off interneurons, with a 27 ± 14 Hz firing activity that stops at the beginning of (and during) the OSP. We suggest that these OSP-associated neurons belong to a descending RAS, which contributes to the activation of the spinal central pattern generators. PMID:24303193

  15. Intersegmental coordination of cockroach locomotion: adaptive control of centrally coupled pattern generator circuits

    Directory of Open Access Journals (Sweden)

    Einat eFuchs

    2011-01-01

    Full Text Available Animals’ ability to demonstrate both stereotyped and adaptive locomotor behavior is largely dependent on the interplay between centrally-generated motor patterns and the sensory inputs that shape them. We utilized a combined experimental and theoretical approach to investigate the relative importance of CPG interconnections vs. intersegmental afferents in the cockroach: an animal that is renowned for rapid and stable locomotion. We simultaneously recorded coxal levator and depressor motor neurons (MN in the thoracic ganglia of Periplaneta americana, while sensory feedback was completely blocked or allowed only from one intact stepping leg. In the absence of sensory feedback, we observed a coordination pattern with consistent phase relationship that shares similarities with a double tripod gait, suggesting central, feedforward control. This intersegmental coordination pattern was then reinforced in the presence of sensory feedback from a single stepping leg. Specifically, we report on transient stabilization of phase differences between activity recorded in the middle and hind thoracic MN following individual front-leg steps, suggesting a role for afferent phasic information in the coordination of motor circuits at the different hemiganglia. Data were further analyzed using stochastic models of coupled oscillators and maximum likelihood techniques to estimate underlying physiological parameters, such as uncoupled endogenous frequencies of hemisegmental oscillators and coupling strengths and directions. We found that descending ipsilateral coupling is stronger than ascending coupling, while left-right coupling in both the meso- and meta-thoracic ganglia appear to be symmetrical. We discuss our results in comparison with recent findings in stick insects that share similar neural and body architectures, and argue that the two species may exemplify opposite extremes of a fast-slow locomotion continuum, mediated through different intersegmental

  16. Symmetry-Breaking in a Rate Model for a Biped Locomotion Central Pattern Generator

    Directory of Open Access Journals (Sweden)

    Ian Stewart

    2014-01-01

    Full Text Available The timing patterns of animal gaits are produced by a network of spinal neurons called a Central Pattern Generator (CPG. Pinto and Golubitsky studied a four-node CPG for biped dynamics in which each leg is associated with one flexor node and one extensor node, with Ζ2 x Ζ2 symmetry. They used symmetric bifurcation theory to predict the existence of four primary gaits and seven secondary gaits. We use methods from symmetric bifurcation theory to investigate local bifurcation, both steady-state and Hopf, for their network architecture in a rate model. Rate models incorporate parameters corresponding to the strengths of connections in the CPG: positive for excitatory connections and negative for inhibitory ones. The three-dimensional space of connection strengths is partitioned into regions that correspond to the first local bifurcation from a fully symmetric equilibrium. The partition is polyhedral, and its symmetry group is that of a tetrahedron. It comprises two concentric tetrahedra, subdivided by various symmetry planes. The tetrahedral symmetry arises from the structure of the eigenvalues of the connection matrix, which is involved in, but not equal to, the Jacobian of the rate model at bifurcation points. Some of the results apply to rate equations on more general networks.

  17. Dynamic control of a central pattern generator circuit: a computational model of the snail feeding network.

    Science.gov (United States)

    Vavoulis, Dimitris V; Straub, Volko A; Kemenes, Ildikó; Kemenes, György; Feng, Jianfeng; Benjamin, Paul R

    2007-05-01

    Central pattern generators (CPGs) are networks underlying rhythmic motor behaviours and they are dynamically regulated by neuronal elements that are extrinsic or intrinsic to the rhythmogenic circuit. In the feeding system of the pond snail, Lymnaea stagnalis, the extrinsic slow oscillator (SO) interneuron controls the frequency of the feeding rhythm and the N3t (tonic) has a dual role; it is an intrinsic CPG interneuron, but it also suppresses CPG activity in the absence of food, acting as a decision-making element in the feeding circuit. The firing patterns of the SO and N3t neurons and their synaptic connections with the rest of the CPG are known, but how these regulate network function is not well understood. This was investigated by building a computer model of the feeding network based on a minimum number of cells (N1M, N2v and N3t) required to generate the three-phase motor rhythm together with the SO that was used to activate the system. The intrinsic properties of individual neurons were represented using two-compartment models containing currents of the Hodgkin-Huxley type. Manipulations of neuronal activity in the N3t and SO neurons in the model produced similar quantitative effects to food and electrical stimulation in the biological network indicating that the model is a useful tool for studying the dynamic properties of the feeding circuit. The model also predicted novel effects of electrical stimulation of two CPG interneurons (N1M and N2v). When tested experimentally, similar effects were found in the biological system providing further validation of our model. PMID:17561845

  18. The Contribution of a Central Pattern Generator in a Reflex-Based Neuromuscular Model

    Directory of Open Access Journals (Sweden)

    Florin Dzeladini

    2014-06-01

    Full Text Available Although the concept of central pattern generators (CPGs controlling locomotion in vertebrates is widely accepted, the presence of specialized CPGs in human locomotion is still a matter of debate. An interesting numerical model developed in the 90s' demonstrated the important role CPGs could play in human locomotion, both in terms of stability against perturbations, and in terms of speed control. Recently, a reflex-based neuro-musculo-skeletal model has been proposed, showing a level of stability to perturbations similar to the previous model, without any CPG components. Although exhibiting striking similarities with human gaits, the lack of CPG makes the control of speed/step length in the model difficult. In this paper, we hypothesize that a CPG component will offer a meaningful way of controlling the locomotion speed. After introducing the CPG component in the reflex model, and taking advantage of the resulting properties, a simple model for gait modulation is presented.The results highlight the advantages that a feedforward component can have in terms of gait modulation.

  19. Setting the pace: new insights into central pattern generator interactions in box jellyfish swimming.

    Science.gov (United States)

    Stöckl, Anna Lisa; Petie, Ronald; Nilsson, Dan-Eric

    2011-01-01

    Central Pattern Generators (CPGs) produce rhythmic behaviour across all animal phyla. Cnidarians, which have a radially symmetric nervous system and pacemaker centres in multiples of four, provide an interesting comparison to bilaterian animals for studying the coordination between CPGs. The box jellyfish Tripedalia cystophora is remarkable among cnidarians due to its most elaborate visual system. Together with their ability to actively swim and steer, they use their visual system for multiple types of behaviour. The four swim CPGs are directly regulated by visual input. In this study, we addressed the question of how the four pacemaker centres of this radial symmetric cnidarian interact. We based our investigation on high speed camera observations of the timing of swim pulses of tethered animals (Tripedalia cystophora) with one or four rhopalia, under different simple light regimes. Additionally, we developed a numerical model of pacemaker interactions based on the inter pulse interval distribution of animals with one rhopalium. We showed that the model with fully resetting coupling and hyperpolarization of the pacemaker potential below baseline fitted the experimental data best. Moreover, the model of four swim pacemakers alone underscored the proportion of long inter pulse intervals (IPIs) considerably. Both in terms of the long IPIs as well as the overall swim pulse distribution, the simulation of two CPGs provided a better fit than that of four. We therefore suggest additional sources of pacemaker control than just visual input. We provide guidelines for future research on the physiological linkage of the cubozoan CPGs and show the insight from bilaterian CPG research, which show that pacemakers have to be studied in their bodily and nervous environment to capture all their functional features, are also manifest in cnidarians. PMID:22073288

  20. A Combination of Central Pattern Generator-based and Reflex-based Neural Networks for Dynamic, Adaptive, Robust Bipedal Locomotion

    DEFF Research Database (Denmark)

    Di Canio, Giuliano; Larsen, Jørgen Christian; Wörgötter, Florentin;

    2016-01-01

    Robotic systems inspired from humans have always been lightening up the curiosity of engineers and scientists. Of many challenges, human locomotion is a very difficult one where a number of different systems needs to interact in order to generate a correct and balanced pattern. To simulate...... the interaction of these systems, implementations with reflexbased or central pattern generator (CPG)-based controllers have been tested on bipedal robot systems. In this paper we will combine the two controller types, into a controller that works with both reflex and CPG signals. We use a reflex-based neural...... network to generate basic walking patterns of a dynamic bipedal walking robot (DACBOT) and then a CPG-based neural network to ensure robust walking behavior...

  1. Integration of vision and central pattern generator based locomotion for path planning of a non-holonomic crawling humanoid robot

    OpenAIRE

    Gay, Sébastien; Dégallier Rochat, Sarah; Ijspeert, Auke; Santos-Victor, José

    2010-01-01

    In this paper we present our work on integrating a locomotion controller based on central pattern generator (CPG) and a motion planning algorithm using artificial potential fields for a non-holonomic crawling humanoid robot, the iCub. We also integrated a vision tracker and an inverse kinematics solver to perform reaching tasks. We study the influence of the various parameters of the potential field equations on the performance of the system and prove the efficiency of our framework by testin...

  2. Design of Spiking Central Pattern Generators for Multiple Locomotion Gaits in Hexapod Robots by Christiansen Grammar Evolution.

    Science.gov (United States)

    Espinal, Andres; Rostro-Gonzalez, Horacio; Carpio, Martin; Guerra-Hernandez, Erick I; Ornelas-Rodriguez, Manuel; Sotelo-Figueroa, Marco

    2016-01-01

    This paper presents a method to design Spiking Central Pattern Generators (SCPGs) to achieve locomotion at different frequencies on legged robots. It is validated through embedding its designs into a Field-Programmable Gate Array (FPGA) and implemented on a real hexapod robot. The SCPGs are automatically designed by means of a Christiansen Grammar Evolution (CGE)-based methodology. The CGE performs a solution for the configuration (synaptic weights and connections) for each neuron in the SCPG. This is carried out through the indirect representation of candidate solutions that evolve to replicate a specific spike train according to a locomotion pattern (gait) by measuring the similarity between the spike trains and the SPIKE distance to lead the search to a correct configuration. By using this evolutionary approach, several SCPG design specifications can be explicitly added into the SPIKE distance-based fitness function, such as looking for Spiking Neural Networks (SNNs) with minimal connectivity or a Central Pattern Generator (CPG) able to generate different locomotion gaits only by changing the initial input stimuli. The SCPG designs have been successfully implemented on a Spartan 6 FPGA board and a real time validation on a 12 Degrees Of Freedom (DOFs) hexapod robot is presented. PMID:27516737

  3. Design of Spiking Central Pattern Generators for Multiple Locomotion Gaits in Hexapod Robots by Christiansen Grammar Evolution

    Science.gov (United States)

    Espinal, Andres; Rostro-Gonzalez, Horacio; Carpio, Martin; Guerra-Hernandez, Erick I.; Ornelas-Rodriguez, Manuel; Sotelo-Figueroa, Marco

    2016-01-01

    This paper presents a method to design Spiking Central Pattern Generators (SCPGs) to achieve locomotion at different frequencies on legged robots. It is validated through embedding its designs into a Field-Programmable Gate Array (FPGA) and implemented on a real hexapod robot. The SCPGs are automatically designed by means of a Christiansen Grammar Evolution (CGE)-based methodology. The CGE performs a solution for the configuration (synaptic weights and connections) for each neuron in the SCPG. This is carried out through the indirect representation of candidate solutions that evolve to replicate a specific spike train according to a locomotion pattern (gait) by measuring the similarity between the spike trains and the SPIKE distance to lead the search to a correct configuration. By using this evolutionary approach, several SCPG design specifications can be explicitly added into the SPIKE distance-based fitness function, such as looking for Spiking Neural Networks (SNNs) with minimal connectivity or a Central Pattern Generator (CPG) able to generate different locomotion gaits only by changing the initial input stimuli. The SCPG designs have been successfully implemented on a Spartan 6 FPGA board and a real time validation on a 12 Degrees Of Freedom (DOFs) hexapod robot is presented. PMID:27516737

  4. Stable Walking of Humanoid Robots Using Vertical Center of Mass and Foot Motions by an Evolutionary Optimized Central Pattern Generator

    Directory of Open Access Journals (Sweden)

    Young-Dae Hong

    2016-02-01

    Full Text Available This paper proposes a method to produce the stable walking of humanoid robots by incorporating the vertical center of mass (COM and foot motions, which are generated by the evolutionary optimized central pattern generator (CPG, into the modifiable walking pattern generator (MWPG. The MWPG extends the conventional 3-D linear inverted pendulum model (3-D LIPM by allowing a zero moment point (ZMP variation. The disturbance caused by the vertical COM motion is compensated in real time by the sensory feedback in the CPG. In this paper, the vertical foot trajectory of the swinging leg, as well as the vertical COM trajectory of the 3-D LIPM, are generated by the CPG for the effective compensation of the disturbance. Consequently, using the proposed method, the humanoid robot is able to walk with a vertical COM and the foot motions generated by the CPG, while modifying its walking patterns by using the MWPG in real time. The CPG with the sensory feedback is optimized to obtain the desired output signals. The optimization of the CPG is formulated as a constrained optimization problem with equality constraints and is solved by two-phase evolutionary programming (TPEP. The validity of the proposed method is verified through walking experiments for the small-sized humanoid robot, HanSaRam-IX (HSR-IX.

  5. Modular organization of the multipartite central pattern generator for turtle rostral scratch: knee-related interneurons during deletions.

    Science.gov (United States)

    Stein, Paul S G; Daniels-McQueen, Susan; Lai, Jessica; Liu, Z; Corman, Tanya S

    2016-06-01

    Central pattern generators (CPGs) are neuronal networks in the spinal cord that generate rhythmic patterns of motor activity in the absence of movement-related sensory feedback. For many vertebrate rhythmic behaviors, CPGs generate normal patterns of motor neuron activities as well as variations of the normal patterns, termed deletions, in which bursts in one or more motor nerves are absent from one or more cycles of the rhythm. Prior work with hip-extensor deletions during turtle rostral scratch supports hypotheses of hip-extensor interneurons in a hip-extensor module and of hip-flexor interneurons in a hip-flexor module. We present here single-unit interneuronal recording data that support hypotheses of knee-extensor interneurons in a knee-extensor module and of knee-flexor interneurons in a knee-flexor module. Members of knee-related modules are not members of hip-related modules and vice versa. These results in turtle provide experimental support at the single-unit interneuronal level for the organizational concept that the rostral-scratch CPG for the turtle hindlimb is multipartite, that is, composed of more than two modules. This work, when combined with experimental and computational work in other vertebrates, does not support the classical view that the vertebrate limb CPG is bipartite with only two modules, one controlling all the flexors of the limb and the other controlling all the extensors of the limb. Instead, these results support the general principle that spinal CPGs are multipartite. PMID:27030737

  6. Preclinical evidence supporting the clinical development of central pattern generator-modulating therapies for chronic spinal cord-injured patients

    Directory of Open Access Journals (Sweden)

    Pierre eGuertin

    2014-05-01

    Full Text Available Ambulation or walking is one of the main gaits of locomotion. In terrestrial animals, it may be defined as a series of rhythmic and bilaterally coordinated movement of the limbs which creates a forward movement of the body. This applies regardless of the number of limbs - from arthropods with six or more limbs to bipedal primates. These fundamental similarities among species may explain why comparable neural systems and cellular properties have been found, thus far, to control in similar ways locomotor rhythm generation in most animal models. The aim of this article is to provide a comprehensive review of the known structural and functional features associated with central nervous system (CNS networks that are involved in the control of ambulation and other stereotyped motor patterns - specifically Central Pattern Generators (CPGs that produce basic rhythmic patterned outputs for locomotion, micturition, ejaculation, and defecation. Although there is compelling evidence of their existence in humans, CPGs have been most studied in reduced models including in vitro isolated preparations, genetically-engineered mice and spinal cord-transected animals. Compared with other structures of the CNS, the spinal cord is generally considered as being well-preserved phylogenetically. As such, most animal models of SCI should be considered as valuable tools for the development of novel pharmacological strategies aimed at modulating spinal activity and restoring corresponding functions in chronic spinal cord-injured patients.

  7. Physiological and pathophysiological interactions between the respiratory central pattern generator and the sympathetic nervous system.

    Science.gov (United States)

    Molkov, Yaroslav I; Zoccal, Daniel B; Baekey, David M; Abdala, Ana P L; Machado, Benedito H; Dick, Thomas E; Paton, Julian F R; Rybak, Ilya A

    2014-01-01

    Respiratory modulation seen in the sympathetic nerve activity (SNA) implies that the respiratory and sympathetic networks interact. During hypertension elicited by chronic intermittent hypoxia (CIH), the SNA displays an enhanced respiratory modulation reflecting strengthened interactions between the networks. In this chapter, we review a series of experimental and modeling studies that help elucidate possible mechanisms of sympatho-respiratory coupling. We conclude that this coupling significantly contributes to both the sympathetic baroreflex and the augmented sympathetic activity after exposure to CIH. This conclusion is based on the following findings. (1) Baroreceptor activation results in perturbation of the respiratory pattern via transient activation of postinspiratory neurons in the Bötzinger complex (BötC). The same BötC neurons are involved in the respiratory modulation of SNA, and hence provide an additional pathway for the sympathetic baroreflex. (2) Under hypercapnia, phasic activation of abdominal motor nerves (AbN) is accompanied by synchronous discharges in SNA due to the common source of this rhythmic activity in the retrotrapezoid nucleus (RTN). CIH conditioning increases the CO2 sensitivity of central chemoreceptors in the RTN which results in the emergence of AbN and SNA discharges under normocapnic conditions similar to those observed during hypercapnia in naïve animals. Thus, respiratory-sympathetic interactions play an important role in defining sympathetic output and significantly contribute to the sympathetic activity and hypertension under certain physiological or pathophysiological conditions, and the theoretical framework presented may be instrumental in understanding of malfunctioning control of sympathetic activity in a variety of disease states. PMID:25194190

  8. Monoaminergic and catecholaminergic activation of the central pattern generator for locomotion following spinal cord injury Innovative therapeutic approaches

    Institute of Scientific and Technical Information of China (English)

    Pierre A.Guertin

    2009-01-01

    The development of secondary health complications following spinal cord injury has been increasingly recognized by healthcare professionals as a major concern.These problems most specifically affect complete or near-complete spinal cord injury patients (e.g.,those with minimal mobility),who are not typically rehabilitated with treadmill training approaches,because motor control and leg movements are largely impaired.However,recent pharmaceutical advances in central pattern generator activation may provide new therapeutic hopes for these spinal cord injury patients.This article provides a comprehensive overview,for the non-specialist,of the most recent advances in this field.

  9. Central pattern generators for a common semiology in fronto-limbic seizures and in parasomnias. A neuroethologic approach.

    Science.gov (United States)

    Tassinari, C A; Rubboli, G; Gardella, E; Cantalupo, G; Calandra-Buonaura, G; Vedovello, M; Alessandria, M; Gandini, G; Cinotti, S; Zamponi, N; Meletti, S

    2005-12-01

    Central pattern generators (CPGs) are genetically determined neuronal aggregates in the mesencephalon, pons and spinal cord subserving innate motor behaviours essential for survival (feeding, locomotion, reproduction etc.). In higher primates CPGs are largely under neocortical control. We describe how certain motor events observed in parasomnias and epileptic seizures could have similar features and resemble motor behaviours, which can be the expression of the same CPG. Both epilepsy and sleep can lead to a temporary loss of control of neomammalian cortex that facilitates through a common platform (arousal) the emergences of stereotyped inborn fixed action patterns. Therefore we suggest that, independently from the nature of the trigger, be it a seizure or a parasomnia, the same CPGs can be involved, "caught up", leading to a common motor semiology (the "Carillon theory"). PMID:16331401

  10. Control strategies of 3-cell Central Pattern Generator via global stimuli

    Science.gov (United States)

    Lozano, Álvaro; Rodríguez, Marcos; Barrio, Roberto

    2016-03-01

    The study of the synchronization patterns of small neuron networks that control several biological processes has become an interesting growing discipline. Some of these synchronization patterns of individual neurons are related to some undesirable neurological diseases, and they are believed to play a crucial role in the emergence of pathological rhythmic brain activity in different diseases, like Parkinson’s disease. We show how, with a suitable combination of short and weak global inhibitory and excitatory stimuli over the whole network, we can switch between different stable bursting patterns in small neuron networks (in our case a 3-neuron network). We develop a systematic study showing and explaining the effects of applying the pulses at different moments. Moreover, we compare the technique on a completely symmetric network and on a slightly perturbed one (a much more realistic situation). The present approach of using global stimuli may allow to avoid undesirable synchronization patterns with nonaggressive stimuli.

  11. Multiple Chaotic Central Pattern Generators with Learning for Legged Locomotion and Malfunction Compensation

    DEFF Research Database (Denmark)

    Ren, Guanjiao; Chen, Weihai; Dasgupta, Sakyasingha;

    2015-01-01

    on a simulated annealing algorithm. In a normal situation, the CPGs synchronize and their dynamics are identical. With leg malfunction or disability, the CPGs lose synchronization leading to independent dynamics. In this case, the learning mechanism is applied to automatically adjust the remaining legs...... chaotic CPG controller has difficulties dealing with leg malfunction. Specifically, in the scenarios presented here, its movement permanently deviates from the desired trajectory. To address this problem, we extend the single chaotic CPG to multiple CPGs with learning. The learning mechanism is based...... in a physical simulation of a quadruped as well as a hexapod robot and finally in a real six-legged walking machine called AMOSII. The experimental results presented here reveal that using multiple CPGs with learning is an effective approach for adaptive locomotion generation where, for instance, different body...

  12. A Novel Approach to Locomotion Learning: Actor-Critic Architecture using Central Pattern Generators and Dynamic Motor Primitives

    Directory of Open Access Journals (Sweden)

    Cai eLi

    2014-10-01

    Full Text Available In this article, we propose an architecture of a bio-inspired controller that addresses the problem of learning different locomotion gaits for different robot morphologies. The modelling objective is split into two: baseline motion modelling and dynamics adaptation. Baseline motion modelling aims to achieve fundamental functions of a certain type of locomotion and dynamics adaptation provides a ``reshaping function for adapting the baseline motion to desired motion. Based on this assumption, a three-layer architecture is developed using central pattern generators (CPGs, a bio-inspired locomotor center for the the baseline motion and dynamic motor primitives (DMPs, a model with universal ``reshaping functions. In this article, we use this architecture with the actor-critic algorithms for finding a good ``reshaping function. In order to demonstrate the learning power of the actor-critic based architecture, we tested it on two experiments: 1 learning to crawl on a humanoid and, 2 learning to gallop on a puppy robot. Two types of actor-critic algorithms (policy search and policy gradient are compared in order to evaluate the advantages and disadvantages of different actor-critic based learning algorithms for different morphologies. Finally, based on the analysis of the experimental results, a generic view/architecture for locomotion learning is discussed in the conclusion.

  13. A novel approach to locomotion learning: Actor-Critic architecture using central pattern generators and dynamic motor primitives.

    Science.gov (United States)

    Li, Cai; Lowe, Robert; Ziemke, Tom

    2014-01-01

    In this article, we propose an architecture of a bio-inspired controller that addresses the problem of learning different locomotion gaits for different robot morphologies. The modeling objective is split into two: baseline motion modeling and dynamics adaptation. Baseline motion modeling aims to achieve fundamental functions of a certain type of locomotion and dynamics adaptation provides a "reshaping" function for adapting the baseline motion to desired motion. Based on this assumption, a three-layer architecture is developed using central pattern generators (CPGs, a bio-inspired locomotor center for the baseline motion) and dynamic motor primitives (DMPs, a model with universal "reshaping" functions). In this article, we use this architecture with the actor-critic algorithms for finding a good "reshaping" function. In order to demonstrate the learning power of the actor-critic based architecture, we tested it on two experiments: (1) learning to crawl on a humanoid and, (2) learning to gallop on a puppy robot. Two types of actor-critic algorithms (policy search and policy gradient) are compared in order to evaluate the advantages and disadvantages of different actor-critic based learning algorithms for different morphologies. Finally, based on the analysis of the experimental results, a generic view/architecture for locomotion learning is discussed in the conclusion. PMID:25324773

  14. Evolution of central pattern generators for the control of a five-link planar bipedal walking mechanism

    CERN Document Server

    Baydin, Atilim Gunes

    2008-01-01

    With the aim of producing a stable human-like bipedal gait, a five-link planar walking mechanism was coupled with a central pattern generator (CPG) network, consisting of units based on Matsuoka's half-center oscillator model. As a minimalistic approach to bipedal walking, this type of walking mechanism contains only four actuators (two in the hip joints and two in the knee joints), and is lacking feet and ankles. Firstly, the mechanism was designed and built as a physical simulation programmed from scratch, providing a platform for hand-tuned tests and the creation of a CPG controller by genetic algorithms (GA). The oscillatory characteristics of the CPG network together with its internal connection structure and the feedback pathways from the environment were subject to GA optimization. The approach proved successful and the results were then transferred to a hardware realization of the five-link walking mechanism, to test how well these perform under real-world dynamics. Results suggest that the biological...

  15. Simulation Platform of Underwater Quadruped Walking Robot Based on MotionGenesis Kane 5 3 and Central Pattern Generator

    Institute of Scientific and Technical Information of China (English)

    Ke Yang; XuYang Wang; Tong Ge; Chao Wu

    2014-01-01

    It will still in lack of a simulation platform used to learn the walking of underwater quadruped walking robot. In order to alleviate this shortage, a simulation platform for the underwater quadruped walking robot based on Kane dynamic model and CPG-based controller is constructed. The Kane dynamic model of the underwater quadruped walking robot is processed with a commercial package MotionGenesis Kane 5�3. The forces between the feet and ground are represented as a spring and damper. The relation between coefficients of spring and damper and stability of underwater quadruped walking robot in the stationary state is studied. The CPG-based controller consisted of Central Pattern Generator ( CPG) and PD controller is presented, which can be used to control walking of the underwater quadruped walking robot. The relation between CPG parameters and walking speed of underwater quadruped walking robot is investigated. The relation between coefficients of spring and damper and walking speed of underwater quadruped walking robot is studied. The results show that the simulation platform can imitate the stable walking of the underwater quadruped walking robot.

  16. Pattern Based Graph Generator

    CERN Document Server

    Shuai, Hong-Han; Yu, Philip S; Shen, Chih-Ya; Chen, Ming-Syan

    2013-01-01

    The importance of graph mining has been widely recognized thanks to a large variety of applications in many areas, while real datasets always play important roles to examine the solution quality and efficiency of a graph mining algorithm. Nevertheless, the size of a real dataset is usually fixed and constrained according to the available resources, such as the efforts to crawl an on-line social network. In this case, employing a synthetic graph generator is a possible way to generate a massive graph (e.g., billions nodes) for evaluating the scalability of an algorithm, and current popular statistical graph generators are properly designed to maintain statistical metrics such as total node degree, degree distribution, diameter, and clustering coefficient of the original social graphs. Nevertheless, in addition to the above metrics, recent studies on graph mining point out that graph frequent patterns are also important to provide useful implications for the corresponding social networking applications, but thi...

  17. GENERATING DISCOURSE THROUGH PATTERNS

    Directory of Open Access Journals (Sweden)

    Gina Necula

    2006-05-01

    Full Text Available When trying to analyse the ways of generating a discourse, one can easily understand that this process presupposes a collage of already made linguistic structures likely to be decoded by speakers under certain conditions such as: sharing the same code, assigning the same meaning to the structure in case, etc. Linguistic patterns are condensed formulas communicating universal wisdom whose occurrence in the discourse confers argumentative authority. Originating in former or present lingua franca and being widely recognized, such structures have inroaded into other languages, preserving the same strategic use in view of reaching persuasive goals.

  18. 基于中枢模式发生器的仿人机器人步态规划%Humanoid robot gait planning based on Central Pattern Generator

    Institute of Scientific and Technical Information of China (English)

    李正文; 张国良; 张维平; 羊帆

    2011-01-01

    对Matsuoka振荡器进行了分析,根据仿人机器人步态规划的要求,选用Matsuoka振荡器构建了中枢模式发生器(CPG)网络;采用遗传算法(GA)来调整网络的参数,解决了关键的网络参数调整的问题;根据CPG网络的输出结果,控制仿人机器人的相应关节,实现了仿人机器人基本步态规划。通过ADAMS进行了仿真,结果表明,该控制策略具有较理想的效果,并且原理简单,易于实现。%The Matsuoka oscillator was analyzed, according to the humanoid robot gait planning requirements, the Matsuoka oscillator was selected to construct the Central Pattern Generator (CPG) network, using genetic algorithms (GA) to adjust the network parameters, the key network parameter adjustment problem was solved; according to the CPG network output results, the humanoid robot relevant joint was controlled, the basic gait planning of the humanoid robot was achieved. Through the ADAMS simulation, the results show that this control strategy has an ideal effect, and the principle is simple, easy to implement.

  19. Generation Y Online Buying Patterns

    Directory of Open Access Journals (Sweden)

    Katija Vojvodić

    2015-12-01

    Full Text Available The advantages of electronic retailing can, among other things, result in uncontrolled buying by online consumers, i.e. in extreme buying behavior. The main purpose of this paper is to analyze and determine the buying patterns of Generation Y online consumers in order to explore the existence of different types of behavior based on the characteristics of online buying. The paper also aims at exploring the relationship between extracted factors and Generation Y consumers’ buying intentions. Empirical research was conducted on a sample of 515 consumers in the Dubrovnik-Neretva County. Based on the factor analysis, research results indicate that Generation Y online consumers are influenced by three factors: compulsivity, impulsivity, and functionality. The analysis of variance reveals that significant differences exist between the extracted factors and Generation Y’s online buying characteristics. In addition, correlation analysis shows a statistically significant correlation between the extracted factors and Generation Y’s buying intentions.

  20. Generation of central exclusive final states

    CERN Document Server

    Lönnblad, Leif

    2016-01-01

    We present a scheme for the generation of central exclusive final states in the Pythia 8 program. The implementation allows for the investigation of higher order corrections to such exclusive processes as approximated by the initial-state parton shower in Pythia 8. To achieve this, the spin and colour decomposition of the initial-state shower has been worked out, in order to determine the probability that a partonic state generated from an inclusive sub-process followed by a series of initial-state parton splittings can be considered as an approximation of an exclusive colour- and spin-singlet process. We use our implementation to investigate effects of parton showers on some examples of central exclusive processes, and find sizeable effects on di-jet production, while the effects on e.g. central exclusive Higgs production are minor.

  1. Airflow Pattern Generated by Three Air Diffusers

    DEFF Research Database (Denmark)

    Olmedo, Inés; Nielsen, Peter V.; Ruiz de Adana, Manuel;

    2011-01-01

    The correct description of air diffusers plays a crucial role in the CFD predictions of the airflow pattern into a room. The numerical simulation of air distribution in an indoor space is challenging because of the complicated airflow pattern generated. Many authors have developed simplified geom...

  2. Legume Diversity Patterns in West Central Africa

    NARCIS (Netherlands)

    Estrella, de la M.; Mateo, M.A.; Wieringa, J.J.; Mackinder, B.; Munoz, J.

    2012-01-01

    Objectives - Species Distribution Models (SDMs) are used to produce predictions of potential Leguminosae diversity in West Central Africa. Those predictions are evaluated subsequently using expert opinion. The established methodology of combining all SDMs is refined to assess species diversity withi

  3. EXPLAINING TRAFFIC FLOW PATTERNS USING CENTRALITY MEASURES

    Directory of Open Access Journals (Sweden)

    Amila Jayasinghe

    2015-06-01

    Full Text Available This study examines the capability of centrality parameters of the road network to explain and predict traffic flow by types of vehicles. The case study was conducted in Colombo Metropolitan Area, Sri Lanka. Study used four centrality parameters i.e. connectivity, global integration, local integration and choice; and three analysis methods i.e. topological, metric and angular which introduced by space syntax analysis method to compute network centrality of the road network. Findings of this study stress that, (1 human beings perceive the space mostly from geometrical distance (topological and angular distance in comparison to metric distance. Further to this, it was found that angular distance is more powerful in global level whereas topological distance is more powerful in local level; (2 it is more appropriate to consider the multiple influences from multiple centrality parameters rather being confined to a single best parameter and influence of each parameter varies based on type of vehicles.

  4. Legume Diversity Patterns in West Central Africa

    OpenAIRE

    Estrella, de la, M.; M. A. Mateo; Wieringa, J. J.; Mackinder, B.; Munoz, J

    2012-01-01

    Objectives - Species Distribution Models (SDMs) are used to produce predictions of potential Leguminosae diversity in West Central Africa. Those predictions are evaluated subsequently using expert opinion. The established methodology of combining all SDMs is refined to assess species diversity within five defined vegetation types. Potential species diversity is thus predicted for each vegetation type respectively. The primary aim of the new methodology is to define, in more detail, areas of s...

  5. A periodic pattern generator for dental diversity

    Directory of Open Access Journals (Sweden)

    Streelman J Todd

    2008-07-01

    Full Text Available Abstract Background Periodic patterning of iterative structures is a fundamental process during embryonic organization and development. Studies have shown how gene networks are employed to pattern butterfly eyespots, fly bristles and vertebrate epithelial appendages such as teeth, feathers, hair and mammary glands. Despite knowledge of how these features are organized, little is known about how diversity in periodic patterning is generated in nature. We address this problem through the molecular analysis of oral jaw dental diversity in Lake Malawi cichlids, where closely related species exhibit from 1 to 20 rows of teeth, with total teeth counts ranging from around 10 to 700. Results We investigate the expression of conserved gene networks (involving bmp2, bmp4, eda, edar, fgf8, pax9, pitx2, runx2, shh and wnt7b known to pattern iterative structures and teeth in other vertebrates. We show that spatiotemporal variation in expression pattern reflects adult morphological diversity among three closely related Malawi cichlid species. Combinatorial epithelial expression of pitx2 and shh appears to govern the competence both of initial tooth sites and future tooth rows. Epithelial wnt7b and mesenchymal eda are expressed in the inter-germ and inter-row regions, and likely regulate the spacing of these shh-positive units. Finally, we used chemical knockdown to demonstrate the fundamental role of hedgehog signalling and initial placode formation in the organization of the periodically patterned cichlid dental programme. Conclusion Coordinated patterns of gene expression differ among Malawi species and prefigure the future-ordered distribution of functional teeth of specific size and spacing. This variation in gene expression among species occurs early in the developmental programme for dental patterning. These data show how a complex multi-rowed vertebrate dentition is organized and how developmental tinkering of conserved gene networks during iterative

  6. Prevalence and pattern of mandibular fracture in Central India

    OpenAIRE

    Barde, Dhananjay; Mudhol, Anupama; Madan, Ramnik

    2014-01-01

    Introduction: The etiology and pattern of mandibular fracture vary considerably among different study populations. Despite many reports about the incidence, diagnosis and treatment of mandibular fracture there is limited knowledge about the specific type or pattern of mandibular fractures in South Asian countries. This study attempts to delineate predictable patterns of fracture based on patient demographics and mechanism of injury in central part of India. Materials and Methods: The medical ...

  7. Enhancing SAT-Based Test Pattern Generation

    Institute of Scientific and Technical Information of China (English)

    LIU Xin; XIONG You-lun

    2005-01-01

    This paper presents modeling tools based on Boolean satisfiability (SAT) to solve problems of test generation for combinational circuits. It exploits an added layer to maintain circuit-related information and value justification relations to a generic SAT algorithm. It dovetails binary decision graphs (BDD) and SAT techniques to improve the efficiency of automatic test pattern generation (ATPG). More specifically, it first exploits inexpensive reconvergent fanout analysis of circuit to gather information on the local signal correlation by using BDD learning, then uses the above learned information to restrict and focus the overall search space of SAT-based ATPG. Its learning technique is effective and lightweight. The experimental results demonstrate the effectiveness of the approach.

  8. Automatic Test Pattern Generation for Digital Circuits

    Directory of Open Access Journals (Sweden)

    S. Hemalatha

    2014-04-01

    Full Text Available Digital circuits complexity and density are increasing and at the same time it should have more quality and reliability. It leads with high test costs and makes the validation more complex. The main aim is to develop a complete behavioral fault simulation and automatic test pattern generation (ATPG system for digital circuits modeled in verilog and VHDL. An integrated Automatic Test Generation (ATG and Automatic Test Executing/Equipment (ATE system for complex boards is developed here. An approach to use memristors (resistors with memory in programmable analog circuits. The Main idea consists in a circuit design in which low voltages are applied to memristors during their operation as analog circuit elements and high voltages are used to program the memristor’s states. This way, as it was demonstrated in recent experiments, the state of memristors does not essentially change during analog mode operation. As an example of our approach, we have built several programmable analog circuits demonstrating memristor -based programming of threshold, gain and frequency. In these circuits the role of memristor is played by a memristor emulator developed by us. A multiplexer is developed to generate a class of minimum transition sequences. The entire hardware is realized as digital logical circuits and the test results are simulated in Model sim software. The results of this research show that behavioral fault simulation will remain as a highly attractive alternative for the future generation of VLSI and system-on-chips (SoC.

  9. Generation of Adaptive Gait Patterns for Quadruped Robot with CPG Network including Motor Dynamic Model

    Science.gov (United States)

    Son, Yurak; Kamano, Takuya; Yasuno, Takashi; Suzuki, Takayuki; Harada, Hironobu

    This paper describes the generation of adaptive gait patterns using new Central Pattern Generators (CPGs) including motor dynamic models for a quadruped robot under various environment. The CPGs act as the flexible oscillators of the joints and make the desired angle of the joints. The CPGs are mutually connected each other, and the sets of their coupling parameters are adjusted by genetic algorithm so that the quadruped robot can realize the stable and adequate gait patterns. As a result of generation, the suitable CPG networks for not only a walking straight gait pattern but also rotation gait patterns are obtained. Experimental results demonstrate that the proposed CPG networks are effective to automatically adjust the adaptive gait patterns for the tested quadruped robot under various environment. Furthermore, the target tracking control based on image processing is achieved by combining the generated gait patterns.

  10. The central government power generating capacity- reforms and the future

    International Nuclear Information System (INIS)

    The alarming resource gap that the states were facing in 1970's has prompted the Central Government to augment the resources for power generation by creating two new entities in November 1975 viz the National Thermal Power Corporation (NTPC) and National Hydro Power Corporation (NHPC). Few other organisations also exist in central sector which are engaged in power generation like Nuclear Power Corporation (NPC). NTPC being the leading player in the power sector, it can neither be indifferent nor dissociate itself from the reforms sweeping the sector today. The article describes the Central Government's role in power generation, reforms and NTPC and further prospects of NTPC

  11. Pattern of skin diseases among Central African refugees in Chad

    OpenAIRE

    Ahmed Fawzi Ismael; Abdel-Hady El-Gilany

    2015-01-01

    Aim: to describe the pattern of skin diseases among refugees attending the dermatology clinic in refugee camps in southern Chad. Methods: A descriptive clinic-based cross-sectional study was done in two refugee camps of people from Republic of Central Africa in Southern Chad. Diagnosis of skin diseases was done through clinical examination by a single dermatologist along with the help of hand lens provided with illumination. Lack of investigations and other skin diagnostic tools prevented fur...

  12. On the generation of coastal lows in central Chile

    International Nuclear Information System (INIS)

    Previous studies of the coastal-low occurrences in central Chile have been aimed at the formulation of a conceptual model to explain observed features in connection with applied studies. The most prominent weather pattern associated with CL occurrences, (type A), coincides with the onset of a warm, middle-troposphere ridge over central Chile, and a surface high over northern Argentina. The synoptic forcing of the low is related to weak frontal disturbances that travel equatorwards. They result in a thickening of the marine layer that becomes blocked by the coastal escarpment, at the time of the onset of the ridge aloft. The blocking of the stable air above the subsidence inversion by the Andes is also hypothesized. The analysis of the subsidence inversion, the geometry of the coastal and Andes mountain ranges, and a scale analysis of the non-dimensional governing equations for the generation of the coastal lows, following the approach of Reason and Steyn (1990); leads to the conclusion that both blocking actions are strong and persistent in central Chile. An interactive mechanism between the upper and lower blocking effects is postulated to explain the cyclonic vorticity and the initial steering of the coastal lows. The scale analysis of the governing equations for the propagation stage of the low suggests that, departing for the South African case, non-linearity is important here, and that solitary Kelvin waves could be expected. Theoretical phase propagation speeds and Rossby radii are found to range between 8 and 15 m s-1 and 100-250 km, respectively. The importance of strong southerly winds ahead of the low and weak winds at its trailing edge is also stressed, as another major departure from the coastal-low behaviour elsewhere. (author). 17 refs, 4 figs, 4 tabs

  13. Generating IDS Attack Pattern Automatically Based on Attack Tree

    Institute of Scientific and Technical Information of China (English)

    向尕; 曹元大

    2003-01-01

    Generating attack pattern automatically based on attack tree is studied. The extending definition of attack tree is proposed. And the algorithm of generating attack tree is presented. The method of generating attack pattern automatically based on attack tree is shown, which is tested by concrete attack instances. The results show that the algorithm is effective and efficient. In doing so, the efficiency of generating attack pattern is improved and the attack trees can be reused.

  14. Generation 1.5 Written Error Patterns: A Comparative Study

    Science.gov (United States)

    Doolan, Stephen M.; Miller, Donald

    2012-01-01

    In an attempt to contribute to existing research on Generation 1.5 students, the current study uses quantitative and qualitative methods to compare error patterns in a corpus of Generation 1.5, L1, and L2 community college student writing. This error analysis provides one important way to determine if error patterns in Generation 1.5 student…

  15. Pattern Generation by Bubble Packing Method

    Directory of Open Access Journals (Sweden)

    Goel V.K.

    2013-06-01

    Full Text Available This paper presents a new computational method forornamental Pattern design. The work is a concerted effort ofevaluation of various methods and the comparatively betterprocess is used for designing keeping in mind the accuracyrequirement for such Indian traditional ethnic designs. The firststep in the process to apply the CAD tools to design the patterns.Small semantics (profile are made using the mathematicalmodelling to make different pattern. Geometric constraints suchas scaling, rotation, transformation etc. are applied to make andmodify the profiles. To create patterns, obtains node locationsthrough a physically based particle simulation, which we call'bubble packing. Bubbles are closely packed on the corners,edges and on the surface domain, and nodes are placed at thecenters of the bubbles. Experimental results show that ourmethod can create high quality ornamental patterns. Thefabrication of the ornaments is on rapid prototype machine.

  16. Pattern Generation by Dissipative Parametric Instability

    Science.gov (United States)

    Perego, A. M.; Tarasov, N.; Churkin, D. V.; Turitsyn, S. K.; Staliunas, K.

    2016-01-01

    Nonlinear instabilities are responsible for spontaneous pattern formation in a vast number of natural and engineered systems, ranging from biology to galaxy buildup. We propose a new instability mechanism leading to pattern formation in spatially extended nonlinear systems, which is based on a periodic antiphase modulation of spectrally dependent losses arranged in a zigzag way: an effective filtering is imposed at symmetrically located wave numbers k and -k in alternating order. The properties of the dissipative parametric instability differ from the features of both key classical concepts of modulation instabilities, i.e., the Benjamin-Feir instability and the Faraday instabiltyity. We demonstrate how the dissipative parametric instability can lead to the formation of stable patterns in one- and two-dimensional systems. The proposed instability mechanism is generic and can naturally occur or can be implemented in various physical systems.

  17. Reproduction Patterns of Scleractinian Corals in the Central Red Sea

    KAUST Repository

    Bouwmeester, Jessica

    2013-12-01

    Early work on the reproductive seasonality of corals in the Red Sea suggested that corals exhibit temporal reproductive isolation, unlike on the Great Barrier Reef where many species spawn in synchrony. More recent work has however shown high synchrony in the maturity of gametes in Acropora species, suggesting multi-specific spawning is likely to occur in the Red Sea. In this thesis I investigate the patterns of coral reproduction in the central Red Sea. The spawning season in the central Red Sea lasts four months, from April to July and spawning occurs on nights around the full moon. During this period Acropora species show a peak of spawning in April, with some species spawning again in May. The level of synchrony, quantified with a spawning synchrony index, is comparable to other locations where multi-specific spawning has been reported. Observations over two consecutive years show that the synchrony of spawning was lower in spring 2012 than in spring 2011, and thus that spawning patterns are variable from one year to the other. Coral settlement patterns on artificial substrata confirmed a main spawning season in the spring but also supported reproductive data suggesting that some Porites spawn in October-November. Settlement was studied over 2.5 years on a reef, which had suffered recently from high mortality after a local bleaching event. Settlement appeared low but post-bleaching studies from other locations indicated similar abundances and showed that recruits generally did not increase until 5 years after the bleaching event. Abundance of juvenile corals however started to increase significantly three years after the bleaching. Successful recruitment, although low suggests that the coral assemblage on the affected reef will most likely recover as long as it is not affected by another disturbance.

  18. MRI in central nervous system infections: A simplified patterned approach

    Institute of Scientific and Technical Information of China (English)

    Krithika; Rangarajan; Chandan; J; Das; Atin; Kumar; Arun; Kumar; Gupta

    2014-01-01

    Recognition and characterization of central nervous system infections poses a formidable challenge to the neuro-radiologist.Imaging plays a vital role,the lesions typically being relatively inaccessible to tisue sampling.The results of an accurate diagnosis are endlessly re-warding,given the availability of excellent pharmaco-logical regimen.The availability of numerous magnetic resonance(MR)sequences which provide functional and molecular information is a powerful tool in the hands of the radiologist.However,the plethora of se-quences and the possibilities on each sequence is also intimidating,and often confusing as well as time con-suming.While a large number of reviews have already described in detail the possible imaging findings in each infection,we intend to classify infections based on their imaging characteristics.In this review we describe an algorithm for first classifying the imaging findings into patterns based on basic MR sequences(T1,T2 and enhancement pattern with Gadolinium),and then sub-classify them based on more advanced molecular and functional sequences(Diffusion,Perfusion,Susceptibili-ty imaging,MR Spectroscopy).This patterned approachis intended as a guide to radiologists in-training and in-practice for quickly narrowing their list of differentials when faced with a clinical challenge.The entire content of the article has also been summarised in the form of flow-charts for the purpose of quick reference.

  19. MRI in central nervous system infections: A simplified patterned approach.

    Science.gov (United States)

    Rangarajan, Krithika; Das, Chandan J; Kumar, Atin; Gupta, Arun Kumar

    2014-09-28

    Recognition and characterization of central nervous system infections poses a formidable challenge to the neuro-radiologist. Imaging plays a vital role, the lesions typically being relatively inaccessible to tisue sampling. The results of an accurate diagnosis are endlessly rewarding, given the availability of excellent pharmacological regimen. The availability of numerous magnetic resonance (MR) sequences which provide functional and molecular information is a powerful tool in the hands of the radiologist. However, the plethora of sequences and the possibilities on each sequence is also intimidating, and often confusing as well as time consuming. While a large number of reviews have already described in detail the possible imaging findings in each infection, we intend to classify infections based on their imaging characteristics. In this review we describe an algorithm for first classifying the imaging findings into patterns based on basic MR sequences (T1, T2 and enhancement pattern with Gadolinium), and then sub-classify them based on more advanced molecular and functional sequences (Diffusion, Perfusion, Susceptibility imaging, MR Spectroscopy). This patterned approach is intended as a guide to radiologists in-training and in-practice for quickly narrowing their list of differentials when faced with a clinical challenge. The entire content of the article has also been summarised in the form of flow-charts for the purpose of quick reference. PMID:25276314

  20. Pattern Visualization Through Detection Plane Generation for Macroscopic Imagery

    OpenAIRE

    Hanan Hassan Ali Adlan

    2016-01-01

    Macroscopic images are kind of environments in which complex patterns are present. Satellite images are one of these classes where many patterns are present. This fact reflects the challenges in detecting patterns present in this kind of environments. SPOT1b satellite images provide valuable information. These images are affordable and can be applicable in wide applications. This paper demonstrates an approach to generate detection plane that visualize patterns present in the satellite image....

  1. Texture Pattern Generation Using Clonal Mosaic

    Institute of Scientific and Technical Information of China (English)

    How Jiann Teo; Kok Cheong Wong

    2006-01-01

    In this paper, an effective system for synthesizing animal skin patterns on arbitrary polygonal surfaces is developed. To accomplish the task, a system inspired by the Clonal Mosaic (CM) model is proposed. The CM model simulates cells' reactions on arbitrary surface. By controlling the division, mutation and repulsion of cells, a regulated spatial arrangement of cells is formed. This arrangement of cells shows appealing result, which is comparable with those natural patterns observed from animal skin. However, a typical CM simulation process incurs high computational cost, where the distances among cells across a polygonal surface are measured and the movements of cells are constrained on the surface. In this framework, an approach is proposed to transform each of the original 3D geometrical planes of the surface into its Canonical Reference Plane Structure. This structure helps to simplify a 3D computational problem into a more manageable 2D problem. Furthermore, the concept of Local Relaxation is developed to optimally enhance the relaxation process for a typical CM simulation. The performances of the proposed solution methods have been verified with extensive experimental results.

  2. Identification of Bacteria by Patterns Generated from Odor Spectra

    CERN Document Server

    Chang, Hung-Chih; King, Maria D; Kwan, Chiman

    2009-01-01

    We use the power density spectra obtained by fluctuation-enhanced sensing of bacterial odors (Escherichia coli and Anthrax-surrogate Bacillus subtilis) to generate new, highly distinguishable, types of patterns based on the average slope of the spectra in different frequency ranges. Such plots can be considered as "fingerprints" of bacterial odors. Three different ways of pattern generation are tested, including a simple binary version. The obtained patterns are simple enough to identify the situation by the naked eye without a pattern recognizer.

  3. Comparison of the reliability of multifocal visual evoked cortical potentials generated by pattern reversal and pattern pulse stimulation

    Directory of Open Access Journals (Sweden)

    G.S. Souza

    2012-10-01

    Full Text Available This study compared the effectiveness of the multifocal visual evoked cortical potentials (mfVEP elicited by pattern pulse stimulation with that of pattern reversal in producing reliable responses (signal-to-noise ratio >1.359. Participants were 14 healthy subjects. Visual stimulation was obtained using a 60-sector dartboard display consisting of 6 concentric rings presented in either pulse or reversal mode. Each sector, consisting of 16 checks at 99% Michelson contrast and 80 cd/m² mean luminance, was controlled by a binary m-sequence in the time domain. The signal-to-noise ratio was generally larger in the pattern reversal than in the pattern pulse mode. The number of reliable responses was similar in the central sectors for the two stimulation modes. At the periphery, pattern reversal showed a larger number of reliable responses. Pattern pulse stimuli performed similarly to pattern reversal stimuli to generate reliable waveforms in R1 and R2. The advantage of using both protocols to study mfVEP responses is their complementarity: in some patients, reliable waveforms in specific sectors may be obtained with only one of the two methods. The joint analysis of pattern reversal and pattern pulse stimuli increased the rate of reliability for central sectors by 7.14% in R1, 5.35% in R2, 4.76% in R3, 3.57% in R4, 2.97% in R5, and 1.78% in R6. From R1 to R4 the reliability to generate mfVEPs was above 70% when using both protocols. Thus, for a very high reliability and thorough examination of visual performance, it is recommended to use both stimulation protocols.

  4. Comparison of the reliability of multifocal visual evoked cortical potentials generated by pattern reversal and pattern pulse stimulation.

    Science.gov (United States)

    Souza, G S; Schakelford, H B; Moura, A L A; Gomes, B D; Ventura, D F; Fitzgerald, M E C; Silveira, L C L

    2012-10-01

    This study compared the effectiveness of the multifocal visual evoked cortical potentials (mfVEP) elicited by pattern pulse stimulation with that of pattern reversal in producing reliable responses (signal-to-noise ratio >1.359). Participants were 14 healthy subjects. Visual stimulation was obtained using a 60-sector dartboard display consisting of 6 concentric rings presented in either pulse or reversal mode. Each sector, consisting of 16 checks at 99% Michelson contrast and 80 cd/m² mean luminance, was controlled by a binary m-sequence in the time domain. The signal-to-noise ratio was generally larger in the pattern reversal than in the pattern pulse mode. The number of reliable responses was similar in the central sectors for the two stimulation modes. At the periphery, pattern reversal showed a larger number of reliable responses. Pattern pulse stimuli performed similarly to pattern reversal stimuli to generate reliable waveforms in R1 and R2. The advantage of using both protocols to study mfVEP responses is their complementarity: in some patients, reliable waveforms in specific sectors may be obtained with only one of the two methods. The joint analysis of pattern reversal and pattern pulse stimuli increased the rate of reliability for central sectors by 7.14% in R1, 5.35% in R2, 4.76% in R3, 3.57% in R4, 2.97% in R5, and 1.78% in R6. From R1 to R4 the reliability to generate mfVEPs was above 70% when using both protocols. Thus, for a very high reliability and thorough examination of visual performance, it is recommended to use both stimulation protocols. PMID:22782556

  5. The Generation system of Textile Pattern draft Based on Quasi-regular Pattern Theory

    Directory of Open Access Journals (Sweden)

    Suyi Liu

    2009-10-01

    Full Text Available The quasi-regular patterns generated from hamiltonian has unique balanced symmetry. The patterns are quite suitable for the textile fabric. However the number of patterns just generated from hamiltonian are limited. Therefore in this paper a 110 of functions built by the methods of hamiltonian of superposition, nesting, combination and parameter variations, and it can increase the type and quantity. All of functions can generate fine patterns suited for textile fabric after computer graphics.The system of textile pattern draft is generated by Visual basics for the computer. The system allows individual selection of function and parameters to change the pattern and the color conditioning. In this way, it successfully achieves the purpose.

  6. Pattern-Generator-Driven Development in Self-Organizing Models

    OpenAIRE

    Bednar, James A.; Miikkulainen, Risto

    1998-01-01

    Self-organizing models develop realistic cortical structures when given approximations of the visual environment as input. Recently it has been proposed that internally generated input patterns, such as those found in the developing retina and in PGO waves during REM sleep, may have the same effect. Internal pattern generators would constitute an efficient way to specify, develop, and maintain functionally appropriate perceptual organization. They may help express complex structures from mini...

  7. An algorithm for generating quasiperiodic patterns and their approximants

    Indian Academy of Sciences (India)

    E A Lord; K Ramakrishnan; S Ranganathan

    2000-04-01

    An algorithm for projecting the interior of a hypercube in -dimensions on to an -dimensional subspace has been developed and incorporated into a computer program for generating quasiperiodic and periodic patterns in an -dimensional subspace. Some aspects of the resulting orthorhombic approximants to Penrose tiling patterns are discussed and illustrated.

  8. Neogene Topography And Precipitation Patterns Of The Central Anatolian Plateau

    Science.gov (United States)

    Mulch, A.; Mikes, T.; Schemmel, F.; Rojay, B.

    2010-12-01

    Long-term stable isotope records of terrestrial environments represent increasingly important tools for tectonic, paleoaltimetric, and paleoclimatic reconstructions within continental interiors. A rapidly growing number of studies within the Earth’s major mountain ranges demonstrates that the growth of topography and orogenic plateaus profoundly influences local, regional, and hemispheric climate and hence precipitation patterns while regional surface uplift patterns are intimately linked to plate-scale geodynamic processes. In contrast, such records are almost absent for the Near East and the Turkish-Iranian plateau, an important topographic element in the Alpine-Himalayan chain and an area most likely to be strongly affected by future climate change and water scarcity. Our objective is to assess the role of orographic factors that have governed the distribution (and isotopic composition) of precipitation across the central Anatolian plateau (CAP, Turkey) from the Neogene to recent. Such data are fundamental for our understanding of the geodynamic and sedimentary history of orogenic plateaus in general and for the role of surface uplift along the plateau margins in the Pontide and Tauride mountains. We present oxygen, carbon, and hydrogen isotope data from Neogene-to-recent fluvio-lacustrine and pedogenic environments, stream and lake waters of the CAP with the ultimate aim of reconstructing past precipitation changes, plateau aridification and ideally Neogene surface uplift histories. Our approach is to cross-calibrate modern patterns of isotopes (oxygen and hydrogen) in precipitation with pedogenic carbonate oxygen and carbon isotope data across topographic barriers that today strongly control the distribution of rainfall along the plateau margins and within the plateau interior. We then compare these patterns with Miocene-to-Pleistocene lacustrine and pedogenic records to assess a) the role of late Neogene (ca. 8-0 Ma) surface uplift in the Taurus mountains

  9. Pattern of skin diseases among Central African refugees in Chad

    Directory of Open Access Journals (Sweden)

    Ahmed Fawzi Ismael

    2015-08-01

    Full Text Available Aim: to describe the pattern of skin diseases among refugees attending the dermatology clinic in refugee camps in southern Chad. Methods: A descriptive clinic-based cross-sectional study was done in two refugee camps of people from Republic of Central Africa in Southern Chad. Diagnosis of skin diseases was done through clinical examination by a single dermatologist along with the help of hand lens provided with illumination. Lack of investigations and other skin diagnostic tools prevented further confirmation of diagnosis. Data was manually analyzed and diagnosis was presented as number and percent using the ICD -10 of the World Health Organization. Results: A total of 366 dermatologic diseases were diagnosed in 361 patients. Certain infectious and parasitic diseases and dermatitis/ eczema were the commonest diagnostic categories (39.9% and 22.45; respectively followed by disorders of skin appendices (15% and infections of skin and subcutaneous tissues (13.1%. Tinea barbae /capitis, ringworm and impetigo are the commonest recorded infections (11.5%, 10.1% and 7.9%; respectively. Miliaria and acne vulgaris were the most frequent disorders of skin appendages. Conclusions: Infectious skin diseases are common among refugees. There are urgent needs for health education and promotion of personal hygiene with adequate sanitation as well as availability of diagnostic tests [TAF Prev Med Bull 2015; 14(4.000: 324-328

  10. Dynamic array generation and pattern formation for optical tweezers

    DEFF Research Database (Denmark)

    Mogensen, P.C.; Glückstad, J.

    2000-01-01

    The generalised phase contrast approach is used for the generation of optical arrays of arbitrary beam shape, suitable for applications in optical tweezers for the manipulation of biological specimens. This approach offers numerous advantages over current techniques involving the use of computer-......-generated holograms or diffractive optical elements. We demonstrate a low-loss system for generating intensity patterns suitable for the trapping and manipulation of small particles or specimens....

  11. High Quality Test Pattern Generation and Boolean Satisfiability

    CERN Document Server

    Eggersglüß, Stephan

    2012-01-01

    This book provides an overview of automatic test pattern generation (ATPG) and introduces novel techniques to complement classical ATPG, based on Boolean Satisfiability (SAT).  A fast and highly fault efficient SAT-based ATPG framework is presented which is also able to generate high-quality delay tests such as robust path delay tests, as well as tests with long propagation paths to detect small delay defects. The aim of the techniques and methodologies presented in this book is to improve SAT-based ATPG, in order to make it applicable in industrial practice. Readers will learn to improve the performance and robustness of the overall test generation process, so that the ATPG algorithm reliably will generate test patterns for most targeted faults in acceptable run time to meet the high fault coverage demands of industry. The techniques and improvements presented in this book provide the following advantages: Provides a comprehensive introduction to test generation and Boolean Satisfiability (SAT); Describes a...

  12. Programmable pseudo-random detector-pulse-pattern generator

    International Nuclear Information System (INIS)

    This report discusses the design and realization of the digital part of the programmable pseudo-random detector pulse-pattern generator. For the design and realization use has been made of F-TTL and high speed special purpose ic's, in particular FAL's (15 ns). The design possibilities offered by the software for pro-gramming of the FAL's have been utilized as much as possible. In this way counters, registers and a state machine with extended control possibilities have been designed and an advanced 8 channel pulse generator has been developed which is controlled via the VME system bus. the generator possesses an internal clock oscillator of 16 MHZ. The moment when a pulse is generated can be adjusted with a step size of 250 ps. 2000 different periods (time windows) can be stored for generating a pattern. (author). 37 refs.; 6 figs

  13. Double split ring slot FSS reflectarray for difference pattern generation

    OpenAIRE

    Zelenchuk, D.; Fusco, V.

    2013-01-01

    A report is presented on a split ring slot frequency selective surface (FSS) reflector whose element design and distribution allows generation of far-field difference patterns. The reflector operates by converting linearly polarised plane wave fronts into two orthogonal polarisations each with a deep null in the centre of the radiation pattern. The far-field measurement presented is in good agreement with the simulation and demonstrates a null depth of ?20dB in the centre of the radiation pat...

  14. Generation and Analysis of Constrained Random Sampling Patterns

    DEFF Research Database (Denmark)

    Pierzchlewski, Jacek; Arildsen, Thomas

    2016-01-01

    Random sampling is a technique for signal acquisition which is gaining popularity in practical signal processing systems. Nowadays, event-driven analog-to-digital converters make random sampling feasible in practical applications. A process of random sampling is defined by a sampling pattern, which...... indicates signal sampling points in time. Practical random sampling patterns are constrained by ADC characteristics and application requirements. In this paper, we introduce statistical methods which evaluate random sampling pattern generators with emphasis on practical applications. Furthermore, we propose...

  15. COMBINED MINING APPROACH TO GENERATE PATTERNS FOR COMPLEX DATA

    Directory of Open Access Journals (Sweden)

    Sumit Kumar

    2013-02-01

    Full Text Available In Data mining applications, which often involve complex data like multiple heterogeneous data sources, user preferences, decision-making actions and business impacts etc., the complete useful information cannot be obtained by using single data mining method in the form of informative patterns as that would consume more time and space, if and only if it is possible to join large relevant data sources for discovering patterns consisting of various aspects of useful information. We consider combined mining as an approach for mining informative patterns from multiple data-sources or multiple-features or by multiple-methods as per the requirements. In combined mining approach, we applied Lossy-counting algorithm on each data-source to get the frequent data item-sets and then get the combined association rules. In multi-feature combined mining approach, we obtained pair patterns and cluster patterns and then generate incremental pair patterns and incremental cluster patterns, which cannot be directly generated by the existing methods. In multi-method combined mining approach, we combine FP-growth and Bayesian Belief Network to make a classifier to get more informative knowledge.

  16. Modeling Patterns of Precipitation Phase in the Central Sierra Nevada

    Science.gov (United States)

    Strikas, O.; Pavelsky, T.

    2013-12-01

    Snowpack provides 75% of summer hydrologic flow in the western United States. This summer flow is vitally important in California, the country's leading producer of agriculture, with $43.5 billion dollars in cash receipts in 2011. Snowpack in the California Sierra Nevada has declined by approximately half from 1900 to 1990. In this study, we use the Weather Research and Forecasting (WRF) regional climate model at a 3km resolution to understand the critical temperature window at which both snow and rain fall for the Central Sierra Nevada during the 2002 water year. Results suggest that temperature and snow fraction [snowfall / (snowfall + rainfall)] share a logistic relationship with the snow fraction being 1 until approximately 272 K, then the snow fraction decreases by approximately 22%/K leveling at 0 snow fraction at 276.5 K. We further examine the spatial patterns of temperatures, precipitation amounts, and precipitation types in the Sierra Nevada to determine the areas of greatest potential snow to rain transition under a future warmer climate. Preliminary results suggest that the high risk areas are at the low to mid elevations. This research provides evidence that even a minor increase in temperature (+0.5 K) will yield changes in spring and summer hydrographs for the region. The spatial variability of IPCC temperature regime change for 2050 and 2100 will be downscaled for a higher resolution prediction of precipitation. It is currently under investigation how the proposed IPCC (A1 and B2) predictions of climate change for the region by 2050 (+2.7 K; +1.6 K ) and 2100 (+4.4 K; +2.7 K) will alter the corresponding annual river hydrographs. Given the complex topography of the Sierra Nevada, several spatial interpolations using GIS and statistical algorithms will be executed to render this high resolution (3km) output. Other future work with collaborators intends to model the agricultural risk associated with our predicted changes. This plot demonstrates the

  17. Synoptic patterns producing extreme precipitation and floods in Central Europe

    Czech Academy of Sciences Publication Activity Database

    Kašpar, Marek

    Technical University of Liberec, 2013. s. 15. [Precipitation extremes in a changing climate. 24.09.2013-26.09.2013, Hejnice] Institutional support: RVO:68378289 Keywords : extreme precipitation * floods * Central Europe

  18. An Assessment of Future Patterns of Security in Central Asia

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Since the disintegration of the Soviet Union in the early 1990s, various social problems left over have emerged in some Central Asian states, thus threatening social stability in the region. Under globalization, the former Soviet republics in Central Asia have made great efforts to develop constructive relations with others in the hope of strengthening their security. However, the threat of terrorism, extremism and separatism still exists. These non-traditional security issues play a role in current international politics, and the countries in the region are trylng to meet new challenges.

  19. Impacts of Centrally and Non-centrally Planned Distributed Generation on Low Voltage Distribution Network

    Directory of Open Access Journals (Sweden)

    Jun Huat Tang

    2012-01-01

    Full Text Available The introduction of Feed in Tariff (FiT by Malaysian Government in December 2011 has resulted in the increasing number of distributed generators (DG connected to the existing radial low voltage (LV distribution network. It is important to investigate the technical issues caused by anticipated amount of DG, in order to ensure the safety, reliability, and efficiency of the power system. The paper describes a simulation work based on a commercial and residential LV distribution network in the state of Selangor. Both centrally and non-centrally planned distributed generators are studied to investigate the positive and negative impacts of DG connected to the LV distribution network. The voltage unbalance factor in LV distribution network with different penetration level of DG is studied. In addition, the LV network with DGs is also used to minimize the network power losses. The power factor and the voltage unbalance factor at point of coupling are studied. Finally, this simulation work is extended to assess how the cable length from substation to the point of coupling affects the voltage unbalance in the network.

  20. Pattern Visualization Through Detection Plane Generation for Macroscopic Imagery

    Directory of Open Access Journals (Sweden)

    Hanan Hassan Ali Adlan

    2016-02-01

    Full Text Available Macroscopic images are kind of environments in which complex patterns are present. Satellite images are one of these classes where many patterns are present. This fact reflects the challenges in detecting patterns present in this kind of environments. SPOT1b satellite images provide valuable information. These images are affordable and can be applicable in wide applications. This paper demonstrates an approach to generate detection plane that visualize patterns present in the satellite image. The detection plane uses rough neural network to provide optimal representation in backpropagation architecture. Rough set theory combined with multilayer perceptron constitutes the rough neural network. Reduction in the feature dimensionality via the rough module improves the recognition ability of the neural network. It is found that the rough module provides the neural network with optimal features. The ability of the neural network to efficiently detect and visualize the pattern stems from a developed extraction algorithm. The result of the hybrid architecture provides the plane with the best features that visualize the phenomena under investigation. Together with the novel extraction algorithm, the developed system provides a tool to visualize patterns present in SPOT1b Satellite image.

  1. Continuities and changes in infant attachment patterns across two generations.

    Science.gov (United States)

    Raby, K Lee; Steele, Ryan D; Carlson, Elizabeth A; Sroufe, L Alan

    2015-01-01

    This study examined the intergenerational continuities and changes in infant attachment patterns within a higher-risk longitudinal sample of 55 female participants born into poverty. Infant attachment was assessed using the Strange Situation when participants were 12 and 18 months as well as several decades later with participants' children. Paralleling earlier findings from this sample on the stability of attachment patterns from infancy to young adulthood, results provided evidence for intergenerational continuities in attachment disorganization but not security. Children of adults with histories of infant attachment disorganization were at an increased risk of forming disorganized attachments. Although changes in infant attachment patterns across the two generations were not correlated with individuals' caregiving experiences or interpersonal stresses and supports during childhood and adolescence, higher quality social support during adulthood was associated with intergenerational changes from insecure to secure infant-caregiver attachment relationships. PMID:26213155

  2. Precise packet loss pattern generation by intentional interference

    OpenAIRE

    He Z.; Voigt T

    2011-01-01

    Abstract—Intermediate-quality links often cause vulnerable connectivity in wireless sensor networks, but packet losses caused by such volatile links are not easy to trace. In order to equip link layer protocol designers with a reliable test and debugging tool, we develop a reactive interferer to generate packet loss patterns precisely. By using intentional interference to emulate parameterized lossy links with very low intrusiveness, our tool facilitates both robustness evaluation of proto...

  3. A Novel Approach for Association Rule Mining using Pattern Generation

    Directory of Open Access Journals (Sweden)

    Deepa S. Deshpande

    2014-10-01

    Full Text Available Data mining has become a process of significant interest in recent years due to explosive rate of the accumulation of data. It is used to discover potentially valuable implicit knowledge from the large transactional databases. Association rule mining is one of the well known techniques of data mining. It typically aims at discovering associations between attributes in the large databases. The first and the most influential traditional algorithm for association rule discovery is Apriori. Multiple scans of database, generation of large number of candidates item set and discovery of interesting rules are the main challenging issues for the improvement of Apriori algorithm. Therefore in order to decrease the multiple scanning of database, a new method of association rule mining using pattern generation is proposed in this paper. This method involves three steps. First, patterns are generated using items from the transaction database. Second, frequent item set is obtained using these patterns. Finally association rules are derived. The performance of this method is evaluated with the traditional Apriori algorithm. It shows that behavior of the proposed method is much more similar to Apriori algorithm with less memory space and reduction in multiple times scanning of database. Thus it is more efficient than the traditional Apriori algorithm.

  4. Anthropogenic soils in central Amazonia: farmers’ practices, agrobiodiversity and land-use patterns

    NARCIS (Netherlands)

    Braga Junqueira, A.

    2015-01-01

    Keywords: Terra Preta; Amazonian Dark Earths; Shifting cultivation; Homegardens; Intensification; Diversification; Smallholder farming. André Braga Junqueira (2015). Anthropogenic soils in central Amazonia: farmers’ practices, agrobiodiversity and land-use patterns. PhD thesis, Wagening

  5. Diversity of soil macrofauna on different pattern of sloping land agroforestry in Wonogiri, Central Java

    OpenAIRE

    SUNARTO; SUGIYARTO; MARKANTIA ZARRA PERITIKA

    2012-01-01

    Peritika MZ, Sugiyarto, Sunarto. 2012. Diversity of soil macrofauna on different pattern of sloping land agroforestry in Wonogiri, Central Java. Biodiversitas 13: 140-144. The purposes of this study were to determine the diversity level of soil macrofauna on different patterns of sloping land agroforestry, in Wonogiri District, Central Java, and to find out the relationship between environmental factors and the level of soil macrofauna diversity. The study was conducted by sampling at three d...

  6. Use of design pattern layout for automatic metrology recipe generation

    Science.gov (United States)

    Tabery, Cyrus; Page, Lorena

    2005-05-01

    As critical dimension control requirements become more challenging, due to complex designs, aggressive lithography, and the constant need to shrink,metrology recipe generation and design evaluation have also become very complex. Hundreds of unique sites must be measured and monitored to ensure good device performance and high yield. The use of the design and layout for automated metrology recipe generation will be critical to that challenge. The DesignGauge from Hitachi implements a system enabling arbitrary recipe generation and control of SEM observations performed on the wafer, based only on the design information. This concept for recipe generation can reduce the time to develop a technology node from RET and design rule selection, through OPC model calibration and verification, and all the way to high volume manufacturing. Conventional recipe creation for a large number of measurement targets requires a significant amount of engineering time. Often these recipes are used only once or twice during mask and process verification or OPC calibration data acquisition. This process of manual setup and analysis is also potentially error prone. CD-SEM recipe creation typically requires an actual wafer, so the recipe creation cannot occur until the scanner and reticle are in house. All of these problems with conventional CD SEM lead to increased development time and reduced final process quality. The new model of CD-SEM recipe generation and management utilizes design-to-SEM matching technology. This new technology extracts an idealized shape from the designed pattern, and utilizes the shape information for pattern matching. As a result, the designed pattern is used as basis for the template instead of the actual SEM image. Recipe creation can be achieved in a matter of seconds once the target site list is finalized. The sequence of steps for creating a recipe are: generate a target site list, pass the design polygons (GDS) and site list to the CD SEM, define references

  7. Distributed generation and centralized power system in Thailand

    DEFF Research Database (Denmark)

    Sukkumnoed, Decharut

    The paper examines and discusses conflicts between the development of distributed power and centralized power system in Thailand.......The paper examines and discusses conflicts between the development of distributed power and centralized power system in Thailand....

  8. Costs and revenues of centrally generated electricity in the Netherlands

    International Nuclear Information System (INIS)

    The existing statistics on centrally generated electricity in the Netherlands do not give an integral picture of costs and revenues. This report intends to fill this gap. It contains a systematic overview of the costs of fuel, capital, other generation costs and the costs of distribution. A detailed overview is given for 1976 and 1977 and the main trends in the period 1950/1980 are considered. From these trends it appears that the increase of revenues from electricity in the last 30 years (from f 400 mln in 1950 to f 8,000 mln in 1980) has been caused by a tenfold increase of electricity consumption and a doubling of the average nominal kWh-charge. The quadrupling of fuel costs in the last 7 years is responsible for the doubling of this kWh-charge. A correction for inflation (since 1950 5%/year) shows, however, that the real kWh-charge in 1980 is only half the kWh-charge in 1950. A discussion on electricity from incineration is included. Because of increasing fuel charges and the difficulties with the disposal of domestic waste this option must be taken into account for future energy supply. The costs of nuclear power are treated in some detail, partly because of the public interest in this subject. It is shown that the costs of electricity from existing nuclear capacity and the estimates of these costs for new nuclear capacity are subject to an increasing trend. This last statement is true as well for electricity from conventional capacity

  9. Evaluation of second-generation central receiver technologies

    International Nuclear Information System (INIS)

    This paper summarizes the results of a study performed by the US and Germany to assess the technical and economic potential of central receiver power plants and to identify the necessary research and development (R ampersand D) activities required to reach demonstration and commercialization. Second generation power plant designs, employing molten-salt and volumetric-air receivers, were assessed at the size of 30 and 100 MWe. The study developed a common guideline and used data from previous system tests and studies. The levelized-energy costs for the second generation plants were estimated and found to be competitive with costs from fossil-fueled power plants. Potential for further cost reductions exists if technical improvements can be introduced successfully in the long term. Additionally, the study presents results of plant reliability and uncertainty analyses. Mid- and long-term technical potentials are described, as well as recommendations for the R ampersand D activities needed to reach the goal of large-scale commercialization. The results of this study have already helped direct research in the US and Europe. For example, the favorable potential for these technologies has led to the Solar Two molten-salt project in the US and the TSA volumetric receiver test in Spain. In addition, early analysis conducted within this study indicated that an advanced thermal storage medium was necessary to achieve favorable economics for the air plant. This led to the design of the thermal storage system currently being tested in Spain. In summary, each of the investigated receiver technologies has mid- and long-term potential for improving plant performance and reducing capital and energy costs (resulting in less than 10 cts/kWh given excellent insolation conditions) in an environmentally safe way and largely independent of fossil-fuel prices

  10. Pattern Recognition on Read Positioning in Next Generation Sequencing

    Science.gov (United States)

    Byeon, Boseon; Kovalchuk, Igor

    2016-01-01

    The usefulness and the utility of the next generation sequencing (NGS) technology are based on the assumption that the DNA or cDNA cleavage required to generate short sequence reads is random. Several previous reports suggest the existence of sequencing bias of NGS reads. To address this question in greater detail, we analyze NGS data from four organisms with different GC content, Plasmodium falciparum (19.39%), Arabidopsis thaliana (36.03%), Homo sapiens (40.91%) and Streptomyces coelicolor (72.00%). Using machine learning techniques, we recognize the pattern that the NGS read start is positioned in the local region where the nucleotide distribution is dissimilar from the global nucleotide distribution. We also demonstrate that the mono-nucleotide distribution underestimates sequencing bias, and the recognized pattern is explained largely by the distribution of multi-nucleotides (di-, tri-, and tetra- nucleotides) rather than mono-nucleotides. This implies that the correction of sequencing bias needs to be performed on the basis of the multi-nucleotide distribution. Providing companion software to quantify the effect of the recognized pattern on read positioning, we exemplify that the bias correction based on the mono-nucleotide distribution may not be sufficient to clean sequencing bias. PMID:27299343

  11. Research on Optimal Development Pattern of Yunnan Central Economic Region

    Institute of Scientific and Technical Information of China (English)

    Diego Salmero; Suman Rana

    2012-01-01

    By the case study on the Urban Agglomeration Plan of Yunnan Central Economic Region (YCER), which is jointly made by Chinese and Swiss scholars, with the adoption of GIS and traditional urban planning methods, this paper uses multiple scenarios to analyze four development models of "Scattered Yunnan," "Regional Yunnan," "Metropolitan Yunnan" and "Network Yunnan." It also explores the relatively rational scenarios for the future development of YCER, i.e., up to 2030, the development model of YCER will be "Regional," and after 2030 it will be "Network." In this way, YCER will be developed stably and methodically, and finally achieve the unification of ecological safety, intensified energy and resources, as well as prosperous economy.

  12. Pattern recognition receptors and central nervous system repair

    Science.gov (United States)

    Kigerl, Kristina A.; de Rivero Vaccari, Juan Pablo; Dietrich, W. Dalton

    2016-01-01

    Pattern recognition receptors (PRRs) are part of the innate immune response and were originally discovered for their role in recognizing pathogens by ligating specific pathogen associated molecular patterns (PAMPs) expressed by microbes. Now the role of PRRs in sterile inflammation is also appreciated, responding to endogenous stimuli referred to as “damage associated molecular patterns” (DAMPs) instead of PAMPs. The main families of PRRs include Toll-like receptors (TLRs), Nod-like receptors (NLRs), RIG-like receptors (RLRs), AIM2-like receptors (ALRs), and C-type lectin receptors. Broad expression of these PRRs in the CNS and the release of DAMPs in and around sites of injury suggest an important role for these receptor families in mediating post-injury inflammation. Considerable data now show that PRRs are among the first responders to CNS injury and activation of these receptors on microglia, neurons, and astrocytes triggers an innate immune response in the brain and spinal cord. Here we discuss how the various PRR families are activated and can influence injury and repair processes following CNS injury. PMID:25017883

  13. Transition of pattern generation: the phenomenon of post-scratching locomotion.

    Science.gov (United States)

    Trejo, A; Tapia, J A; De la Torre Valdovinos, B; Huidobro, N; Flores, G; Flores-Hernandez, J; Flores, A; Manjarrez, E

    2015-03-12

    A fundamental problem in neurophysiology is the understanding of neuronal mechanisms by which the central nervous system produces a sequence of voluntary or involuntary motor acts from a diverse repertory of movements. These kinds of transitions between motor acts are extremely complex; however, they could be analyzed in a more simple form in decerebrate animals in the context of spinal central pattern generation. Here, we present for the first time a physiological phenomenon of post-scratching locomotion in which decerebrate cats exhibit a compulsory locomotor activity after an episode of scratching. We found flexor, extensor and intermediate single interneurons rhythmically firing in the same phase during both scratching and the subsequent post-scratching locomotion. Because no changes in phase of these neurons from scratching to post-scratching locomotion were found, we suggest that in the lumbar spinal cord there are neurons associated with both motor tasks. Moreover, because of its high reproducibility we suggest that the study of post-scratching fictive locomotion, together with the unitary recording of neurons, could become a useful tool to study neuronal mechanisms underlying transitions from one rhythmic motor task to another, and to study in more detail the central pattern generator circuitry in the spinal cord. PMID:25556832

  14. BUILDOUT AND UPGRADE OF CENTRAL EMERGENCY GENERATOR SYSTEM, GENERATOR 3 AND 4 ELECTRICAL INSTALLATION

    Energy Technology Data Exchange (ETDEWEB)

    Gary D. Seifert; G. Shawn West; Kurt S. Myers; Jim Moncur

    2006-07-01

    SECTION 01000—SUMMARY OF WORK PART 1—GENERAL 1.1 SUMMARY The work to be performed under this project consists of providing the labor, equipment, and materials to perform "Buildout and Upgrade of Central Emergency Generator System, Generator 3 and 4 Electrical Installation" for the National Aeronautics and Space Administration at the Dryden Flight Research Center (NASA/DFRC), Edwards, California 93523. All modifications to existing substations and electrical distribution systems are the responsibility of the contractor. It is the contractor’s responsibility to supply a complete and functionally operational system. The work shall be performed in accordance with these specifications and the related drawings. The work of this project is defined by the plans and specifications contained and referenced herein. This work specifically includes but is not limited to the following: Scope of Work - Installation 1. Install all electrical wiring and controls for new generators 3 and 4 to match existing electrical installation for generators 1 and 2 and in accordance with drawings. Contractor shall provide as-built details for electrical installation. 2. Install battery charger systems for new generators 3 and 4 to match existing battery charging equipment and installation for generators 1 and 2. This may require exchange of some battery charger parts already on-hand. Supply power to new battery chargers from panel and breakers as shown on drawings. Utilize existing conduits already routed to generators 3 and 4 to field route the new wiring in the most reasonable way possible. 3. Install electrical wiring for fuel/lube systems for new generators 3 and 4 to match existing installation for generators 1 and 2. Supply power to lube oil heaters and fuel system (day tanks) from panel and breakers as shown on drawings. Utilize existing conduits already routed to generators 3 and 4 to field route the new wiring in the most reasonable way possible. Add any conduits necessary to

  15. Simplified Process for Manufacturing Macroscale Patterns to Enhance Voltage Generation by a Triboelectric Generator

    Directory of Open Access Journals (Sweden)

    Jun-Ho Yang

    2015-11-01

    Full Text Available This paper proposes a simple, yet effective and affordable, manufacturing process to enhance the overall efficiency of voltage generation by a triboelectric generator (TEG using 3D printers for energy-harvesting applications. The proposed method can be classified as macroscale surface patterning, in contrast to micro- and nanoscale patterning of TEG proposed in previous studies. Experiments were conducted using a designed test-bed system that allowed the control of external factors, such as the magnitude and frequency of the frictional force and the relative humidity, and an output voltage increase of up to 67% was obtained from a TEG with macroscale patterns that increased the surface area by 14%. The peak voltage generated by the TEG was as high as 18 V, and the addition of a designed analog circuit that uses no external power enabled storage of a DC voltage of 0.4 V. In comparison with previous methods that employ micro- or nanoscale patterns, the proposed patterning method is faster and more suitable for mass production.

  16. The Central Electricity Generating Board flask test project

    International Nuclear Information System (INIS)

    In 1981, the UK Central Electricity Generating Board set up a wide-ranging programme of theoretical and experimental work to develop a detailed understanding of the way in which Magnox flasks behave in severe transport accidents. Specific objectives of the project included an investigation into the validity of the use of scale models to represent full-size flask behaviour and the relevance of the IAEA regulatory tests in relation to real transport accidents. In all, over a hundred tests on flask components, model flasks and other test pieces were conducted, culminating in the drop testing of a full-sized Magnox flask and a simulated rail crash test carried out in public in July 1984. The project was based on a steady progression from the study of fundamental principles to the execution of the train crash. Extensive use was made of experimental drop-test facilities and computer-aided analytical techniques, such as the finite element method. The project confirmed that, with some important exceptions, linear scalability can be applied with confidence to predict flask behaviour under impact loading. Where those exceptions were encountered, some guidance was obtained as to how it should be properly accounted for when interpreting scale model data. Good correlation was achieved between finite element analyses (carried out using DYNA-3D and ANSYS) and experimental results. The knowledge gained as a result of developing and running the finite element model proved to be invaluable in developing a high degree of understanding of flask impact behaviour. This knowledge ultimately allowed a series of very simple mathematical models to be developed and used as engineering tools in other studies. (author)

  17. Legume diversity patterns in West Central Africa: influence of species biology on distribution models.

    Directory of Open Access Journals (Sweden)

    Manuel de la Estrella

    Full Text Available OBJECTIVES: Species Distribution Models (SDMs are used to produce predictions of potential Leguminosae diversity in West Central Africa. Those predictions are evaluated subsequently using expert opinion. The established methodology of combining all SDMs is refined to assess species diversity within five defined vegetation types. Potential species diversity is thus predicted for each vegetation type respectively. The primary aim of the new methodology is to define, in more detail, areas of species richness for conservation planning. METHODOLOGY: Using Maxent, SDMs based on a suite of 14 environmental predictors were generated for 185 West Central African Leguminosae species, each categorised according to one of five vegetation types: Afromontane, coastal, non-flooded forest, open formations, or riverine forest. The relative contribution of each environmental variable was compared between different vegetation types using a nonparametric Kruskal-Wallis analysis followed by a post-hoc Kruskal-Wallis Paired Comparison contrast. Legume species diversity patterns were explored initially using the typical method of stacking all SDMs. Subsequently, five different ensemble models were generated by partitioning SDMs according to vegetation category. Ecological modelers worked with legume specialists to improve data integrity and integrate expert opinion in the interpretation of individual species models and potential species richness predictions for different vegetation types. RESULTS/CONCLUSIONS: Of the 14 environmental predictors used, five showed no difference in their relative contribution to the different vegetation models. Of the nine discriminating variables, the majority were related to temperature variation. The set of variables that played a major role in the Afromontane species diversity model differed significantly from the sets of variables of greatest relative important in other vegetation categories. The traditional approach of stacking all

  18. Cat and dog ownership and management patterns in central Italy.

    Science.gov (United States)

    Slater, Margaret R; Di Nardo, Antonio; Pediconi, Ombretta; Villa, Paolo Dalla; Candeloro, Luca; Alessandrini, Barbara; Del Papa, Stefania

    2008-07-15

    Three hundred and ninety-seven randomly selected households were interviewed by telephone to determine the numbers and management of owned cats and dogs in the Teramo Province of Italy. The households were selected using stratified random sampling for each municipality; municipalities were combined into coastal, central hills and mountain regions for analysis. The interviews were completed during May and June of 2004 with a response rate of 74% (397/536). Forty-six percent of households (n=181) owned pets; 15% of all households (n=60) owned cats and 33% (n=130) owned dogs. Twenty-seven of these households (7%) owned both cats and dogs. Data were provided on 91 cats evenly divided between males and females. The median age was 3 years (range 0.2-10 years). Forty-one percent of cats (36/87) entered the household as strays. Nearly half lived entirely outside. Seventy percent (62/88) had visited a veterinarian at least once; 43% (39/91) were sterilized. About 1/3 had had a litter and all litters were considered accidental rather than planned. Age, indoor/outdoor status, veterinarian visit and region were all associated with sterilization. Age, confined to a yard, veterinary visit and region were associated with allowing the cat to roam freely. Data were provided on 182 dogs. Sixty-two percent (113/181) were male, with a median age of 4 years (range newborn to 17 years) and 40% (72/181) were purebred. Almost half were acquired as a gift. Sixty-two percent (112/180) were kept entirely outside despite the fact that 82% (147/180) were considered companions rather than working dogs. Almost all of the dogs had been to a veterinarian at least once; only 20% (n=29) were sterilized. Male dogs were significantly less likely to be sterilized than females. Almost half the dogs had had at least one litter. Seventy-six percent (137/180) of dogs knew some basic commands. Sex, source and training to sit/stay/come were significantly associated with whether the dog was sterilized. Dog

  19. Fast Generation of Best Interval Patterns for Nonmonotonic Constraints

    OpenAIRE

    Buzmakov, Aleksey; Kuznetsov, Sergei O.; Napoli, Amedeo

    2015-01-01

    In pattern mining, the main challenge is the exponential explosion of the set of patterns. Typically, to solve this problem, a constraint for pattern selection is introduced. One of the first constraints proposed in pattern mining is support (frequency) of a pattern in a dataset. Frequency is an anti-monotonic function, i.e., given an infrequent pattern, all its superpatterns are not frequent. However, many other constraints for pattern selection are neither monotonic nor anti-monotonic, whic...

  20. Electric vehicle charge patterns and the electricity generation mix and competitiveness of next generation vehicles

    International Nuclear Information System (INIS)

    Highlights: • The energy system of whole of Japan is analyzed in this study. • An advanced model based on MARKAL is used for the energy system analysis. • The impact of charge patterns of EVs on electricity generation mix is evaluated. • Technology competitiveness of the next generation vehicles is also evaluated. - Abstract: The nuclear accident of 2011 brought about a reconsideration of the future electricity generation mix of power systems in Japan. A debate on whether to phase out nuclear power plants and replace them with renewable energy sources is taking place. Demand-side management becomes increasingly important in future Japanese power systems with a large-scale integration of renewable energy sources. This paper considers the charge control of electric vehicles (EVs) through demand-side management. There have been many studies of the control or operation methods of EVs known as vehicle-to-grid (V2G), and it is important to evaluate both their short-term and long-term operation. In this study, we employ energy system to evaluate the impact of the charge patterns of EVs on both the electricity generation mix and the technology competitiveness of the next generation vehicles. An advanced energy system model based on Market Allocation (MARKAL) is used to consider power system control in detail

  1. The Birth of a "Green" Generation? Generational Dynamics of Resource Consumption Patterns

    OpenAIRE

    Büttner, T.; Grubler, A

    1995-01-01

    The article discusses a generational perspective on changes in lifestyles and consumption patterns that complement more traditional approaches of heterogeneity and path dependency of human behavior. An application is given, in developing a model of cohort and gender-specific diffusion of technological artifacts, applied to the case of car ownership in Germany. The article concludes with a number of research questions to address the complexities of changes in human behavior from an interdiscip...

  2. Learning Techniques for Automatic Test Pattern Generation using Boolean Satisfiability

    Directory of Open Access Journals (Sweden)

    Liu Xin

    2013-07-01

    Full Text Available Automatic Test Pattern Generation (ATPG is one of the core problems in testing of digital circuits. ATPG algorithms based on Boolean Satisfiability (SAT turned out to be very powerful, due to great advances in the performance of satisfiability solvers for propositional logic in the last two decades. SAT-based ATPG clearly outperforms classical approaches especially for hard-to-detect faults. But its inaccessibility of structural information and don’t care, there exists the over-specification problem of input patterns. In this paper we present techniques to delve into an additional layer to make use of structural properties of the circuit and value justification relations to a generic SAT algorithm. It joins binary decision graphs (BDD and SAT techniques to improve the efficiency of ATPG. It makes a study of inexpensive reconvergent fanout analysis of circuit to gather information on the local signal correlation by using BDD learning, then uses the above learned information to restrict and focus the overall search space of SAT-based ATPG. The learning technique is effective and lightweight. Experimental results show the effectiveness of the approach.

  3. A Cyclic Inhibitory Central Pattern Generator Control Method Integrated with Mechanical Oscillators for Snake Robots%融合机械元的蛇形机器人循环抑制中枢模式发生器控制方法

    Institute of Scientific and Technical Information of China (English)

    唐超权; 王明辉; 李斌; 马书根

    2013-01-01

    To solve the problem that there is no basis for choosing control signals and sensor information for central pattern generator (CPG) control of snake robots, a cyclic inhibitory CPG control method with mechanical oscillators is proposed. Firstly, the mechanical oscillators reformed from snake robot dynamical equations are introduced into the cyclic inhibitory CPG model. Secondly, an improved Matsuoka neuron is proposed so that the neuron and mechanical oscillator can be expressed in a uniform way. Thirdly, the relationship of parameters in the cyclic inhibitory CPG model with mechanical oscillators is illustrated, and the relationship expression of the control signal and sensor information for snake robots and the CPG states is given. Finally, the proposed method is verified with simulation, and the simulation results are analyzed. In this method, there are clear definitions for the control signals and sensor information of snake robots, and the computation complexity of CPG is decreased because neuron computation in CPG is replaced with physical structure of mechanical oscillators.%针对蛇形机器人中枢模式发生器(CPG)控制中控制信号以及传感信息缺少选择依据的问题,提出了一种融合了机械元的循环抑制CPG控制方法.首先,将蛇形机器人本体动力学方程改造为机械元引入循环抑制CPG模型.其次,提出了改进的Matsuoka神经元,从而使得神经元与机械元具有一致的表达形式.再次,分析了融入机械元的循环抑制CPG模型中的参数关系,并给出了控制信号和传感信息与CPG状态量关系的表达式.最后,利用仿真对所提出的方法进行了验证,并对产生结果进行了分析.该方法中蛇形机器人的控制信号与传感信息都具有明确的定义,且由于用机械元的物理结构代替了神经元的计算,降低了CPG的计算量.

  4. Impact of Resistant Starch on Body Fat Patterning and Central Appetite Regulation

    OpenAIRE

    So, Po-Wah; Yu, Wei-Sheng; Kuo, Yu-Ting; Wasserfall, Clive; Goldstone, Anthony P.; Bell, Jimmy D; Gary S Frost

    2007-01-01

    Background. Adipose tissue patterning has a major influence on the risk of developing chronic disease. Environmental influences on both body fat patterning and appetite regulation are not fully understood. This study was performed to investigate the impact of resistant starch (RS) on adipose tissue deposition and central regulation of appetite in mice. Methodology and Principle Findings. Forty mice were randomised to a diet supplemented with either the high resistant starch (HRS), or th...

  5. Anthropogenic soils in central Amazonia: farmers’ practices, agrobiodiversity and land-use patterns

    OpenAIRE

    Braga Junqueira, A.

    2015-01-01

    Keywords: Terra Preta; Amazonian Dark Earths; Shifting cultivation; Homegardens; Intensification; Diversification; Smallholder farming. André Braga Junqueira (2015). Anthropogenic soils in central Amazonia: farmers’ practices, agrobiodiversity and land-use patterns. PhD thesis, Wageningen University, The Netherlands, with summary in English, 163 pp. Rural Amazonia is increasingly experiencing environmental and socio-economic changes that directly affect smallholder farmers, with ...

  6. US central station nuclear electric generating units: significant milestones

    International Nuclear Information System (INIS)

    Listings of US nuclear power plants include significant dates, reactor type, owners, and net generating capacity. Listings are made by state, region, and utility. Tabulations of status, schedules, and orders are also presented

  7. Real-time Walking Pattern Generation for a Biped Robot with Hybrid CPG-ZMP Algorithm

    Directory of Open Access Journals (Sweden)

    Bin He

    2014-10-01

    Full Text Available Biped robots have better mobility than conventional wheeled robots. The bio-inspired method based on a central pattern generator (CPG can be used to control biped robot walking in a manner like human beings. However, to achieve stable locomotion, it is difficult to modulate the parameters for the neural networks to coordinate every degree of freedom of the walking robot. The zero moment point (ZMP method is very popular for the stability control of biped robot walking. However, the reference trajectories have low energy efficiency, lack naturalness and need significant offline calculation. This paper presents a new method for biped real-time walking generation using a hybrid CPG-ZMP control algorithm. The method can realize a stable walking pattern by combining the ZMP criterion with rhythmic motion control. The CPG component is designed to generate the desired motion for each robot joint, which is modulated by phase resetting according to foot contact information. By introducing the ZMP location, the activity of the CPG output signal is adjusted to coordinate the limbs’ motion and allow the robot to maintain balance during the process of locomotion. The numerical simulation results show that, compared with the CPG method, the new hybrid CPG-ZMP algorithm can enhance the robustness of the CPG parameters and improve the stability of the robot. In addition, the proposed algorithm is more energy efficient than the ZMP method. The results also demonstrate that the control system can generate an adaptive walking pattern through interactions between the robot, the CPG and the environment.

  8. Solar central electric power generation - A baseline design

    Science.gov (United States)

    Powell, J. C.

    1976-01-01

    The paper presents the conceptual technical baseline design of a solar electric power plant using the central receiver concept, and derives credible cost estimates from the baseline design. The major components of the plant - heliostats, tower, receiver, tower piping, and thermal storage - are discussed in terms of technical and cost information. The assumed peak plant output is 215 MW(e), over 4000 daylight hours. The contribution of total capital investment to energy cost is estimated to be about 55 mills per kwh in mid-1974 dollars.

  9. Centrality and energy dependence of rapidity correlation patterns in relativistic heavy ion collisions

    International Nuclear Information System (INIS)

    The centrality and energy dependence of rapidity correlation patterns are studied in Au + Au collisions by using AMPT with string melting, RQMD and UrQMD models. The behaviors of the short-range correlation (SRC) and the long-range correlation (LRC) are presented clearly by two spatial-position dependent correlation patterns. For centrality dependence, UrQMD and RQMD give similar results as those in AMPT, i.e., in most central collisions, the correlation structure is flatter and the correlation range is larger, which indicates a long range rapidity correlation. A long range rapidity correlation showing up in RQMD and UrQMD implies that parton interaction is not the only source of long range rapidity correlations. For energy dependence, AMPT with string melting and RQMD show quite different results. The correlation patterns in RQMD at low collision energies and those in AMPT at high collision energies have similar structures, i.e. a convex curve, while the correlation patterns in RQMD at high collision energies and those in AMPT at low collision energies show flat structures, having no position dependence. Long range rapidity correlation presents itself at high energy and disappears at low energy in RQMD, which also indicates that long range rapidity correlations may come from some trivial effects, rather than the parton interactions. (authors)

  10. Centrality and energy dependence of rapidity correlation patterns in relativistic heavy ion collisions

    Institute of Scientific and Technical Information of China (English)

    LE Tian; XU Ming-Mei; WU Yuan-Fang

    2011-01-01

    The centrality and energy dependence of rapidity correlation patterns are studied in Au+Au collisions by using AMPT with string melting,RQMD and UrQMD models.The behaviors of the shortrange correlation(SRC)and the long-range correlation(LRC)are presented clearly by two spatial-position dependent correlation patterns.For centrality dependence.UrQMD and RQMD give similar results as those in AMPT,i.,e., in most central collisions,the correlation structure is flatter and the correlation range is larger,which indicates a long range rapidity correlation.A long range rapidity correlation showing up in RQMD and UrQMD implies that patton interaction is not the only source of long range rapidity correlations.For energy dependence,AMPT with string melting and RQMD show quite different results.The correlation patterns in RQMD at low collision energies and those in AMPT at high collision energies have similar structures,i.e.aconvex curve.while the correlation patterns in RQMD at high collision energies and those in AMPT at low collision energies show fiat structures,having no position dependence.Long range rapidity correlation presents itself at high energy and disappears at low energy in RQMD,which also indicates that long range rapidity correlations may come from some trivial effects,rather than the parton interactions.

  11. Major Dietary Patterns in Relation to General and Central Obesity among Chinese Adults.

    Science.gov (United States)

    Yu, Canqing; Shi, Zumin; Lv, Jun; Du, Huaidong; Qi, Lu; Guo, Yu; Bian, Zheng; Chang, Liang; Tang, Xuefeng; Jiang, Qilian; Mu, Huaiyi; Pan, Dongxia; Chen, Junshi; Chen, Zhengming; Li, Liming

    2015-07-01

    Limited evidence exists for the association between diet pattern and obesity phenotypes among Chinese adults. In the present study, we analyzed the cross-sectional data from 474,192 adults aged 30-79 years from the China Kadoorie Biobank baseline survey. Food consumption was collected by an interviewer-administered questionnaire. Three dietary patterns were extracted by factor analysis combined with cluster analysis. After being adjusted for potential confounders, individuals following a traditional southern dietary pattern had the lowest body mass index (BMI) and waist circumference (WC); the Western/new affluence dietary pattern had the highest BMI; and the traditional northern dietary pattern had the highest WC. Compared to the traditional southern dietary pattern in multivariable adjusted logistic models, individuals following a Western/new affluence dietary pattern had a significantly increased risk of general obesity (prevalence ratio (PR): 1.06, 95% confidence interval (CI): 1.03-1.08) and central obesity (PR: 1.07, 95% CI: 1.06-1.08). The corresponding risks for the traditional northern dietary pattern were 1.05 (1.02-1.09) and 1.17 (1.25-1.18), respectively. In addition, the associations were modified by lifestyle behaviors, and the combined effects with alcohol drinking, tobacco smoking, and physical activity were analyzed. Further prospective studies are needed to elucidate the diet-obesity relationships. PMID:26184308

  12. Major Dietary Patterns in Relation to General and Central Obesity among Chinese Adults

    Directory of Open Access Journals (Sweden)

    Canqing Yu

    2015-07-01

    Full Text Available Limited evidence exists for the association between diet pattern and obesity phenotypes among Chinese adults. In the present study, we analyzed the cross-sectional data from 474,192 adults aged 30–79 years from the China Kadoorie Biobank baseline survey. Food consumption was collected by an interviewer-administered questionnaire. Three dietary patterns were extracted by factor analysis combined with cluster analysis. After being adjusted for potential confounders, individuals following a traditional southern dietary pattern had the lowest body mass index (BMI and waist circumference (WC; the Western/new affluence dietary pattern had the highest BMI; and the traditional northern dietary pattern had the highest WC. Compared to the traditional southern dietary pattern in multivariable adjusted logistic models, individuals following a Western/new affluence dietary pattern had a significantly increased risk of general obesity (prevalence ratio (PR: 1.06, 95% confidence interval (CI: 1.03–1.08 and central obesity (PR: 1.07, 95% CI: 1.06–1.08. The corresponding risks for the traditional northern dietary pattern were 1.05 (1.02–1.09 and 1.17 (1.25–1.18, respectively. In addition, the associations were modified by lifestyle behaviors, and the combined effects with alcohol drinking, tobacco smoking, and physical activity were analyzed. Further prospective studies are needed to elucidate the diet-obesity relationships.

  13. Dietary patterns are associated with general and central obesity in elderly living in a Brazilian city

    OpenAIRE

    Priscila Lucelia Moreira; Jose Eduardo Corrente; Paulo Jose Fortes Villas Boas; Ana Lucia Anjos Ferreira

    2014-01-01

    Objective: dietary pattern evaluation is often used in order to determine wheter a diet is healthy, as well as to predict the onset of diseases. This study aimed to identify dietary patterns, and to examine their associations with general (body mass index) and central (waist circumference and waist-to-hip ratio) obesity in community-living elderly in a Brazilian city. Methods: this cross-sectional study included 126 elderly subjects aged 60 or older (57.1% females and mean age 74.2 ± 6.46 y...

  14. An overview of pattern recognition in the central arms of the PHENIX detector

    International Nuclear Information System (INIS)

    It is predicted that a Au+Au event in the PHENIX Detector at RHIC will produce up to 800 charged particles in the PHENIX central arms. Pattern recognition algorithms are being developed to handle this hostile tracking environment. To facilitate the development of these algorithms, a suite of evaluators and event displays have been developed to calculate efficiencies and identify weaknesses in the algorithms. An overview of these algorithms and procedures will be discussed

  15. FORMATION MECHANISM AND SPATIAL PATTERN OF URBAN AGGLOMERATION IN CENTRAL JILIN OF CHINA

    Institute of Scientific and Technical Information of China (English)

    QIN Gan; ZHANG Ping-yu; JIAO Bin

    2006-01-01

    Urban agglomeration is made up of cities with different sizes to be linked by traffic network in a given area, and it is an inevitable result when urbanization reaches a certain level. Taking urban agglomerationin central Jilin(UACJ) as an example, this article analyzes the formation mechanism and spatial pattern of urban agglomeration in the less-developed area. First, the dynamics of UACJ has been analyzed from the aspects of geographical condition, economic foundation, policy background, and traffic condition. Then the development process is divided into three stages-single city, city group and city cluster. Secondly, the central cities are identified from the aspects of city centrality, and the development axes are classified based on economic communication capacity. Finally, the urban agglomeration is divided into five urban economic regions in order to establish the reasonable distribution of industries.

  16. Generation and Analysis of Constrained Random Sampling Patterns

    OpenAIRE

    Pierzchlewski, Jacek; Arildsen, Thomas

    2014-01-01

    Random sampling is a technique for signal acquisition which is gaining popularity in practical signal processing systems. Nowadays, event-driven analog-to-digital converters make random sampling feasible in practical applications. A process of random sampling is defined by a sampling pattern, which indicates signal sampling points in time. Practical random sampling patterns are constrained by ADC characteristics and application requirements. In this paper authors introduce statistical methods...

  17. The genotype-phenotype relationship in multicellular pattern-generating models - the neglected role of pattern descriptors

    Directory of Open Access Journals (Sweden)

    Plahte Erik

    2009-09-01

    Full Text Available Abstract Background A deep understanding of what causes the phenotypic variation arising from biological patterning processes, cannot be claimed before we are able to recreate this variation by mathematical models capable of generating genotype-phenotype maps in a causally cohesive way. However, the concept of pattern in a multicellular context implies that what matters is not the state of every single cell, but certain emergent qualities of the total cell aggregate. Thus, in order to set up a genotype-phenotype map in such a spatiotemporal pattern setting one is actually forced to establish new pattern descriptors and derive their relations to parameters of the original model. A pattern descriptor is a variable that describes and quantifies a certain qualitative feature of the pattern, for example the degree to which certain macroscopic structures are present. There is today no general procedure for how to relate a set of patterns and their characteristic features to the functional relationships, parameter values and initial values of an original pattern-generating model. Here we present a new, generic approach for explorative analysis of complex patterning models which focuses on the essential pattern features and their relations to the model parameters. The approach is illustrated on an existing model for Delta-Notch lateral inhibition over a two-dimensional lattice. Results By combining computer simulations according to a succession of statistical experimental designs, computer graphics, automatic image analysis, human sensory descriptive analysis and multivariate data modelling, we derive a pattern descriptor model of those macroscopic, emergent aspects of the patterns that we consider of interest. The pattern descriptor model relates the values of the new, dedicated pattern descriptors to the parameter values of the original model, for example by predicting the parameter values leading to particular patterns, and provides insights that

  18. Large-Area Protein Patterns Generated by Ordered Binary Colloidal Assemblies as Templates

    DEFF Research Database (Denmark)

    Singh, Gurvinder; Gohri, Vipul; Pillai, Saju;

    2011-01-01

    We demonstrate the use of binary colloidal assemblies as lithographic masks to generate tunable Au patterns on SiO(2) substrates with dimensions ranging from micrometers to nanometers. Such patterns can be modified with different chemistries to create patterns with well-defined sites for selectiv...

  19. Bursts generate a non-reducible spike-pattern code

    Directory of Open Access Journals (Sweden)

    Hugo G Eyherabide

    2009-05-01

    Full Text Available On the single-neuron level, precisely timed spikes can either constitute firing-rate codes or spike-pattern codes that utilize the relative timing between consecutive spikes. There has been little experimental support for the hypothesis that such temporal patterns contribute substantially to information transmission. Using grasshopper auditory receptors as a model system, we show that correlations between spikes can be used to represent behaviorally relevant stimuli. The correlations reflect the inner structure of the spike train: a succession of burst-like patterns. We demonstrate that bursts with different spike counts encode different stimulus features, such that about 20% of the transmitted information corresponds to discriminating between different features, and the remaining 80% is used to allocate these features in time. In this spike-pattern code, the "what" and the "when" of the stimuli are encoded in the duration of each burst and the time of burst onset, respectively. Given the ubiquity of burst firing, we expect similar findings also for other neural systems.

  20. Generation of Shaped beam Radiation patterns from a Line source using Iterative sampling method

    Directory of Open Access Journals (Sweden)

    G.R.L.V.N.Srinivasa Raju

    2013-08-01

    Full Text Available For the generation of cosecant and trapezoidal radiation patterns an iterative sampling method is introduced by Stutzman. In this paper, an original radiation pattern which is some approximation to the desired radiation pattern is generated by a standard synthesis method and a series of correction patterns are applied to it by addinga correction pattern. This process is continued until the desired performance is achieved. In the present work, ramp, sector, cosecant, trapezoidal and stair stepped radiation patterns are generated using iterative procedure. The current distribution is found after corrections are applied. Studies are made with good number of examples, which showed that patterns with low side lobe level or low main beam ripple or sharp cut off from the main beam can be obtained. An iterative procedure is simple and converges rapidly.

  1. PATTERN OF CUTANEOUS DISEASES IN INMATES OF CENTRAL JAIL, LUDHIANA, PUNJAB

    Directory of Open Access Journals (Sweden)

    Bimal

    2014-04-01

    Full Text Available BACKGROUND: Prisons are fertile breeding places for many skin infections and infestations; also the prevalent stressful conditions may aggravate preexisting skin problems. OBJECTIVES: To determine the pattern of cutaneous diseases in Central Jail, Ludhiana, Punjab (male prison. MATERIALS AND METHODS: The jail inmates were examined as a part of special skin camp organized in the Central Jail Ludhiana by the dermatologist after eliciting a brief history. RESULTS: Of the 157 patients examined, 70% were infectious; commonest being scabies followed by pyodermas, dermatophytosis, pityriasis versicolor, warts. Eczemas and Acne vulgaris were the most common non-infectious conditions seen. CONCLUSIONS: We recommend screening of new inmates by a dermatologist and periodic skin camps to be conducted in prisons at regular intervals.

  2. Decreasing overweight and central fat patterning with Westernization among the Inuit in Greenland and Inuit migrants

    DEFF Research Database (Denmark)

    Bjerregaard, P; Jørgensen, M E; Andersen, S;

    2002-01-01

    OBJECTIVE: To analyse overweight, obesity and central fat patterning among the Inuit of Greenland and Inuit migrants in Denmark and their relation to Westernization. DESIGN: Cross-sectional, population-based epidemiological study. SUBJECTS: A total of 2046 adult Greenlanders (Inuit), 61% of those...... estimated by language and place of residence. RESULTS: The prevalence of obesity (>or=30 kg/m(2)) was 16 and 22% among men and women in Greenland (P=0.004), and 12 and 11%, respectively, in Denmark (NS). Westernization was accompanied by a decrease in the proportion of obese people, in particular among...

  3. 32 nm imprint masks using variable shape beam pattern generators

    Science.gov (United States)

    Selinidis, Kosta; Thompson, Ecron; Schmid, Gerard; Stacey, Nick; Perez, Joseph; Maltabes, John; Resnick, Douglas J.; Yeo, Jeongho; Kim, Hoyeon; Eynon, Ben

    2008-05-01

    Imprint lithography has been included on the ITRS Lithography Roadmap at the 32, 22 and 16 nm nodes. Step and Flash Imprint Lithography (S-FIL ®) is a unique method that has been designed from the beginning to enable precise overlay for creating multilevel devices. A photocurable low viscosity monomer is dispensed dropwise to meet the pattern density requirements of the device, thus enabling imprint patterning with a uniform residual layer across a field and across entire wafers. Further, S-FIL provides sub-100 nm feature resolution without the significant expense of multi-element, high quality projection optics or advanced illumination sources. However, since the technology is 1X, it is critical to address the infrastructure associated with the fabrication of templates. For sub-32 nm device manufacturing, one of the major technical challenges remains the fabrication of full-field 1x templates with commercially viable write times. Recent progress in the writing of sub-40 nm patterns using commercial variable shape e-beam tools and non-chemically amplified resists has demonstrated a very promising route to realizing these objectives, and in doing so, has considerably strengthened imprint lithography as a competitive manufacturing technology for the sub 32nm node. Here we report the first imprinting results from sub-40 nm full-field patterns, using Samsung's current flash memory production device design. The fabrication of the template is discussed and the resulting critical dimension control and uniformity are discussed, along with image placement results. The imprinting results are described in terms of CD uniformity, etch results, and overlay.

  4. Propierties of speckle patterns generated through multiaperture pupils

    OpenAIRE

    ??ngel-Toro, Luciano; Tebaldi, Myrian; Trivi, Marcelo; Bolognini, N??stor

    2001-01-01

    The characteristics of the image speckles obtained through multiple aperture pupils are theoretically analyzed in terms of the parameters defining the pupils. The possibility of interpreting and synthesizing the image speckle distribution in terms of rather elementary structures is considered, based on the Fourier optics analysis. Then, first and second order statistical properties of the speckle patterns are studied by evaluating both the mutual intensity and the auto-correlation intensity o...

  5. Interactions between zebrafish pigment cells responsible for the generation of Turing patterns

    OpenAIRE

    Nakamasu, Akiko; Takahashi, Go; Kanbe, Akio; KONDO, Shigeru

    2009-01-01

    The reaction–diffusion system is one of the most studied nonlinear mechanisms that generate spatially periodic structures autonomous. On the basis of many mathematical studies using computer simulations, it is assumed that animal skin patterns are the most typical examples of the Turing pattern (stationary periodic pattern produced by the reaction–diffusion system). However, the mechanism underlying pattern formation remains unknown because the molecular or cellular basis of the phenomenon ha...

  6. Arctic geese during brood-rearing on the central Yukon-Kuskokwim Delta: Analysis of patterns of distribution: Annual report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In July 1985 two systematic aerial surveys were flown over the coastal fringe of the central YukonKuskokwim Delta, Alaska, to examine the patterns of distribution...

  7. Analysing humanly generated random number sequences: A pattern-based approach

    OpenAIRE

    Gravenor, M B; Schulz, M A; Schmalbach, B; Brugger, P; Witt, K.

    2012-01-01

    In a random number generation task, participants are asked to generate a random sequence of numbers, most typically the digits 1 to 9. Such number sequences are not mathematically random, and both extent and type of bias allow one to characterize the brain's “internal random number generator”. We assume that certain patterns and their variations will frequently occur in humanly generated random number sequences. Thus, we introduce a pattern-based analysis of random number sequences. Twenty he...

  8. Analysing Humanly Generated Random Number Sequences: A Pattern-Based Approach

    OpenAIRE

    Schulz, Marc-André; Schmalbach, Barbara; Brugger, Peter; Witt, Karsten

    2012-01-01

    In a random number generation task, participants are asked to generate a random sequence of numbers, most typically the digits 1 to 9. Such number sequences are not mathematically random, and both extent and type of bias allow one to characterize the brain's “internal random number generator”. We assume that certain patterns and their variations will frequently occur in humanly generated random number sequences. Thus, we introduce a pattern-based analysis of random number sequences. Twenty he...

  9. Pattern of Maxillofacial fracture in Western and Central Nepal: An experience in 3 tertiary level health institutions

    OpenAIRE

    S. Subedi; Shrestha, B; RB Adhikari

    2015-01-01

    BACKGROUND: There are only few studies regarding the pattern and causes of maxillofacial fractures till date in Nepal and no such study in western and central Nepalese population has been conducted. The purpose of this study, therefore, was to describe the causes and the pattern of maxillofacial fractures in western and central part of Nepal over the period of 5 years. MATERIAL AND METHODS A retrospective analysis of maxillofacial fractures was conducted on 328 patients who were treated in ...

  10. GENERATING FRACTAL PATTERNS BY USING p-CIRCLE INVERSION

    Science.gov (United States)

    Ramírez, José L.; Rubiano, Gustavo N.; Zlobec, Borut Jurčič

    2015-10-01

    In this paper, we introduce the p-circle inversion which generalizes the classical inversion with respect to a circle (p = 2) and the taxicab inversion (p = 1). We study some basic properties and we also show the inversive images of some basic curves. We apply this new transformation to well-known fractals such as Sierpinski triangle, Koch curve, dragon curve, Fibonacci fractal, among others. Then we obtain new fractal patterns. Moreover, we generalize the method called circle inversion fractal be means of the p-circle inversion.

  11. Strain patterns along the Kaparelli–Asopos rift (central Greece from campaign GPS data

    Directory of Open Access Journals (Sweden)

    Aggeliki Marinou

    2015-06-01

    Full Text Available We present results from four GPS campaigns in the broader Kaparelli–Asopos area in central Greece. This area is undergoing extension as demonstrated by seismological, geodetic and geological data. The east-west striking Kaparelli normal fault ruptured during the March 4, 1981, M = 6.3 earthquake and created km-long surface breaks with the downthrown side to the south. The geodetic results include: determination of station coordinates in the ITRF 2005 frame, computation of station velocities with respect to stable Europe and strain rate tensor estimates. The pattern of velocities along the east-west direction (parallel to the rift axis; 40 km E-W × 12 km N-S and azimuth of strain axes are compared to geological data and to other GPS results in central Greece. We find that strain in this region consists of an amount of shortening (66 ns/yr in the direction approximately N 58°E, and about three times more extension (187 ns/yr at N 32°W. A large change in strain orientation (from NW to NNE is observed from west to east, along the active faults of Asopos rift in agreement with fault slip data. This change signifies the need for using local GPS networks to map local strain rate patterns in actively extending regions of Greece.

  12. From social behavior to neural circuitry: steroid hormones rapidly modulate advertisement calling via a vocal pattern generator.

    Science.gov (United States)

    Remage-Healey, Luke; Bass, Andrew H

    2006-09-01

    Across vertebrates, androgens are rapidly elevated within minutes in response to aggressive or reproductive stimuli, yet it is unclear what the causal relationship is between fast androgen elevation and the ongoing (minute-by-minute) expression of behavior. This study tested the hypothesis that rapid increases in plasma steroid levels induce similarly rapid increases in both vocal behavior and the neurophysiological output of a central pattern generator that governs vocal behavior. In Gulf toadfish (Opsanus beta), males call to attract females to their nesting sites, and both males and females vocalize in aggressive interactions. Previous field experiments with males showed that simulated territorial challenges produce rapid and concurrent elevations in ongoing calling behavior and circulating levels of the teleost-specific androgen 11-ketotestosterone (11kT), but not the glucocorticoid cortisol. The current field experiments showed that non-invasive (food) delivery of 11kT, but not cortisol, induced an elevation within 10 min in the ongoing calling behavior of males. Electrophysiological experiments revealed that intramuscular injections of either 11kT or cortisol, but neither testosterone nor 17-beta-estradiol, induced increases within 5 min in the output of the vocal pattern generator in males, whereas only cortisol had similarly fast effects in females. The field behavioral results support predictions generated by the challenge hypothesis and also parallel the 11kT-dependent modulation of the vocal pattern generator in males. The cortisol effect on the vocal pattern generator in both sexes predicts that glucocorticoids regulate vocalizations in non-advertisement contexts. Together, these experiments provide strong support for the hypothesis that surges in circulating steroid levels play a causal role in shaping rapid changes in social behavior (vocalizations) through non-genomic-like actions on neural (vocal motor) circuits that directly encode behavioral

  13. Directivity patterns of laser-generated sound in solids: Effects of optical and thermal parameters

    CERN Document Server

    Krylov, Victor V

    2014-01-01

    In the present paper, directivity patterns of laser-generated sound in solids are investigated theoretically. Two main approaches to the calculation of directivity patterns of laser-generated sound are discussed for the most important case of thermo-optical regime of generation. The first approach, which is widely used in practice, is based on the simple modelling of the equivalent thermo-optical source as a mechanical dipole comprising two horizontal forces applied to the surface in opposite directions. The second approach is based on the rigorous theory that takes into account all acoustical, optical and thermal parameters of a solid material and all geometrical and physical parameters of a laser beam. Directivity patterns of laser-generated bulk longitudinal and shear elastic waves, as well as the amplitudes of generated Rayleigh surface waves, are calculated for different values of physical and geometrical parameters and compared with the directivity patterns calculated in case of dipole-source representa...

  14. Morphodynamics and anabranching patterns generated in the Madeira River, Brazil

    Science.gov (United States)

    Latrubesse, E. M.; Bonthius, C.; Abad, J. D.; Stevaux, J.; Filizola, N.; Frias, C. E.

    2013-12-01

    The Madeira River is the largest tributary in water discharge and sediment transport of the Amazon River. At present, this river is at the center of a controversial political discussion because the Brazilian government is building two hydroelectric plants on the Bolivia-Brazil border, flooding a long reach from near Cachuela Esperanza in the tributary Beni River, close to the Brazil-Bolivia border, up to Porto Velho. We present results from three field expeditions carried out in July-August 2011, December 2012 and March 2013. The main scope of this article is to disseminate the environmental threat suffered by the Madeira from regulation/disruption, and to present preliminary results on the geomorphologic characteristics of the Madeira channel and floodplain. Using historical radar and satellite imagery, the floodplain morpho-sedimentary units and morphology of the channel were assessed and quantified. Sediment bed and bank sampling, bathymetric surveys and velocity measurements were recorded using a single beam echo sounder and an acoustic Doppler current profiler (ADCP), respectively. Velocity data were analyzed using TRDI's WinRiverII and a MATLAB-based software package Velocity Mapping Tool. We consider that the Madeira River offers some ideal conditions to provide information on critical conditions and geomorphologic thresholds in mega-rivers. The Madeira River has been classified as a simple to moderate anabranching low-sinuosity river. The Madeira flows through a relatively simple pattern, alternating straight reaches with others that exhibit an incipient tendency to anabranch. Single beam and ADCP data yields insight into the bathymetry and flow characteristics in the channel through straight, pseudo-meandering, and anabranching stretches. We studied in detail three selected three reaches zones where three primary mechanisms for anabranching were identified: a) branches upstream and downstream in box shape pseudo-meanders; b) simple branch patterns

  15. Computer-Assisted Generation of Patterns and Virtual Reality Techniques for Fashion Design

    Science.gov (United States)

    Naud, Mickael; Richard, Paul; Chapeau-Blondeau, François

    2009-03-01

    We present a methodology for the design of aesthetic patterns and their visualization on virtual clothes. Generated patterns are directly mapped on the dress of a virtual mannequin. Furthermore, patterns sets may be interactively mapped on the virtual dress using a specific 3D interaction technique called Back-and-Forth. Pattern generation involves different mathematical approaches such as iterated function systems (IFS) and nonlinear trajectory models. Both model parameters and color space exploration is performed through a simple user interface. This work contributes to promote both computer assistance in the context of mass customization for fashion design.

  16. Topology-generating interfacial pattern formation during liquid metal dealloying

    Science.gov (United States)

    Geslin, Pierre-Antoine; McCue, Ian; Gaskey, Bernard; Erlebacher, Jonah; Karma, Alain

    2015-11-01

    Liquid metal dealloying has emerged as a novel technique to produce topologically complex nanoporous and nanocomposite structures with ultra-high interfacial area and other unique properties relevant for diverse material applications. This process is empirically known to require the selective dissolution of one element of a multicomponent solid alloy into a liquid metal to obtain desirable structures. However, how structures form is not known. Here we demonstrate, using mesoscale phase-field modelling and experiments, that nano/microstructural pattern formation during dealloying results from the interplay of (i) interfacial spinodal decomposition, forming compositional domain structures enriched in the immiscible element, and (ii) diffusion-coupled growth of the enriched solid phase and the liquid phase into the alloy. We highlight how those two basic mechanisms interact to yield a rich variety of topologically disconnected and connected structures. Moreover, we deduce scaling laws governing microstructural length scales and dealloying kinetics.

  17. Interference pattern generation and simulation in the single beam of a white light continuum

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    We demonstrate the interference phenomenon in the White Light Continuum(WLC) generated by a single femtosecond laser beam. Different kinds of spatial interference patterns of the WLC generation under various conditions were investigated. The spatial patterns were attributed to interference between the filaments in the WLC generated by the fundamental laser beam yielding the diffraction effect from spatial confinement. Simulations of different patterns were performed. By comparing the results of simulation with those of experiments,the distances of several micrometers between the neighboring filaments can be derived,which agree with the literature values from direct measurements.

  18. Fluid power network for centralized electricity generation in offshore wind farms

    NARCIS (Netherlands)

    Jarquin-Laguna, A.

    2014-01-01

    An innovative and completely different wind-energy conversion system is studied where a centralized electricity generation within a wind farm is proposed by means of a hydraulic network. This paper presents the dynamic interaction of two turbines when they are coupled to the same hydraulic network.

  19. Using Unique-Prime-Factorization Theorem to Mine Frequent Patterns without Generating Tree

    Directory of Open Access Journals (Sweden)

    Hossein Tohidi

    2011-01-01

    Full Text Available Problem statement: Ffrequent patterns are patterns that appear in a data set frequently. Finding such frequent patterns plays an essential role in mining associations, correlations and many other interesting relationships among data. Approach: Most of the previous studies adopt an Apriorilike approach. For huge database it may need to generate a huge number of candidate sets. An interest solution is to design an approach that without generating candidate is able to mine frequent patterns. Results: An interesting method to frequent pattern mining without generating candidate pattern is called frequent-pattern growth, or simply FP-growth, which adopts a divide-and-conquer strategy as follows. However, for a large database, constructing a large tree in the memory is a time consuming task and increase the time of execution. In this study we introduce an algorithm to generate frequent patterns without generating a tree and therefore improve the time complexity and memory complexity as well. Our algorithm works based on prime factorization and is called Prime Factor Miner (PFM. Conclusion/Recommendations: This algorithm is able to achieve low memory order at O(1 which is significantly better than FP-growth.

  20. The Spalt Transcription Factors Generate the Transcriptional Landscape of the Drosophila melanogaster Wing Pouch Central Region

    OpenAIRE

    Organista, María F.; Mercedes Martín; de Celis, Jesus M.; Rosa Barrio; Ana López-Varea; Nuria Esteban; Mar Casado; Celis, Jose F. de

    2015-01-01

    The Drosophila genes spalt major (salm) and spalt-related (salr) encode Zn-finger transcription factors regulated by the Decapentaplegic (Dpp) signalling pathway in the wing imaginal disc. The function of these genes is required for cell survival and proliferation in the central region of the wing disc, and also for vein patterning in the lateral regions. The identification of direct Salm and Salr target genes, and the analysis of their functions, are critical steps towards understanding the ...

  1. Generative Models of Segregation: Investigating Model-Generated Patterns of Residential Segregation by Ethnicity and Socioeconomic Status

    OpenAIRE

    Fossett, Mark

    2011-01-01

    This paper considers the potential for using agent models to explore theories of residential segregation in urban areas. Results of generative experiments conducted using an agent-based simulation of segregation dynamics document that varying a small number of model parameters representing constructs from urban-ecological theories of segregation can generate a wide range of qualitatively distinct and substantively interesting segregation patterns. The results suggest how complex, macro-level ...

  2. Regulated transport as a mechanism for pattern generation: Capabilities for phyllotaxis and beyond

    OpenAIRE

    Sahlin, Patrik; Söderberg, Bo; Jönsson, Henrik

    2009-01-01

    Abstract Large-scale pattern formation is a frequently occurring phenomenon in biological organisms, and several local interaction rules for generating such patterns have been suggested. A mechanism driven by feedback between the plant hormone auxin and its polarly localized transport mediator PINFORMED1 has been proposed as a model for phyllotactic patterns in plants. It has been shown to agree with current biological experiments at a molecular level as well as with respect to the...

  3. Segmentation of turbo generator and reactor coolant pump vibratory patterns: a syntactic pattern recognition approach

    International Nuclear Information System (INIS)

    This study was undertaken in the context of turbogenerator and reactor coolant pump vibration surveillance. Vibration meters are used to monitor equipment condition. An anomaly will modify the signal mean. At the present time, the expert system DIVA, developed to automate diagnosis, requests the operator to identify the nature of the pattern change thus indicated. In order to minimize operator intervention, we have to automate on the one hand classification and on the other hand, detection and segmentation of the patterns. The purpose of this study is to develop a new automatic system for the segmentation and classification of signals. The segmentation is based on syntactic pattern recognition. For the classification, a decision tree is used. The signals to process are the rms values of the vibrations measured on rotating machines. These signals are randomly sampled. All processing is automatic and no a priori statistical knowledge on the signals is required. The segmentation performances are assessed by tests on vibratory signals. (author). 31 figs

  4. Generation of Customizable Micro-wavy Pattern through Grayscale Direct Image Lithography

    Science.gov (United States)

    He, Ran; Wang, Shunqiang; Andrews, Geoffrey; Shi, Wentao; Liu, Yaling

    2016-02-01

    With the increasing amount of research work in surface studies, a more effective method of producing patterned microstructures is highly desired due to the geometric limitations and complex fabricating process of current techniques. This paper presents an efficient and cost-effective method to generate customizable micro-wavy pattern using direct image lithography. This method utilizes a grayscale Gaussian distribution effect to model inaccuracies inherent in the polymerization process, which are normally regarded as trivial matters or errors. The measured surface profiles and the mathematical prediction show a good agreement, demonstrating the ability of this method to generate wavy patterns with precisely controlled features. An accurate pattern can be generated with customizable parameters (wavelength, amplitude, wave shape, pattern profile, and overall dimension). This mask-free photolithography approach provides a rapid fabrication method that is capable of generating complex and non-uniform 3D wavy patterns with the wavelength ranging from 12 μm to 2100 μm and an amplitude-to-wavelength ratio as large as 300%. Microfluidic devices with pure wavy and wavy-herringbone patterns suitable for capture of circulating tumor cells are made as a demonstrative application. A completely customized microfluidic device with wavy patterns can be created within a few hours without access to clean room or commercial photolithography equipment.

  5. Marine litter in Mediterranean sandy littorals: Spatial distribution patterns along central Italy coastal dunes.

    Science.gov (United States)

    Poeta, Gianluca; Battisti, Corrado; Acosta, Alicia T R

    2014-12-15

    Sandy shores are generally considered important sinks for marine litter and the presence of this litter may represent a serious threat to biotic communities and dune integrity mostly due to cleaning activities carried out through mechanical equipment. In spring (April-May) 2012 we sampled 153 2×2m random plots to assess the spatial distribution patterns of litter on Central Italy sandy shores. We analysed the relationship between the presence of litter and coastal dune habitats along the sea-inland gradient. Our results showed that the most frequent litter items were plastic and polystyrene. Differences of marine litter spatial distribution were found between upper beach and fore dune habitats and fixed dune habitats: embryo dune and mobile dune habitats show the highest frequency of litter, but, surprisingly, marine litter did not impact fixed dune habitats, these possibly acting as a natural barrier protecting the inner part of the coast from marine litter dispersion. PMID:25455823

  6. Comparison of large central and small decentralized power generation in India

    Energy Technology Data Exchange (ETDEWEB)

    None

    1997-05-01

    This reports evaluates two options for providing reliable power to rural areas in India. The benefits and costs are compared for biomass based distributed generation (DG) systems versus a 1200-MW central grid coal-fired power plant. The biomass based DG systems are examined both as alternatives to grid extension and as supplements to central grid power. The benefits are divided into three categories: those associated with providing reliable power from any source, those associated specifically with biomass based DG technology, and benefits of a central grid coal plant. The report compares the estimated delivered costs of electricity from the DG systems to those of the central plant. The analysis includes estimates for a central grid coal plant and four potential DG system technologies: Stirling engines, direct-fired combustion turbines, fuel cells, and biomass integrated gasification combined cycles. The report also discusses issues affecting India`s rural electricity demand, including economic development, power reliability, and environmental concerns. The results of the costs of electricity comparison between the biomass DG systems and the coal-fired central grid station demonstrated that the DG technologies may be able to produce very competitively priced electricity by the start of the next century. The use of DG technology may provide a practical means of addressing many rural electricity issues that India will face in the future. Biomass DG technologies in particular offer unique advantages for the environment and for economic development that will make them especially attractive. 58 refs., 31 figs.

  7. Comparison of large central and small decentralized power generation in India

    International Nuclear Information System (INIS)

    This reports evaluates two options for providing reliable power to rural areas in India. The benefits and costs are compared for biomass based distributed generation (DG) systems versus a 1200-MW central grid coal-fired power plant. The biomass based DG systems are examined both as alternatives to grid extension and as supplements to central grid power. The benefits are divided into three categories: those associated with providing reliable power from any source, those associated specifically with biomass based DG technology, and benefits of a central grid coal plant. The report compares the estimated delivered costs of electricity from the DG systems to those of the central plant. The analysis includes estimates for a central grid coal plant and four potential DG system technologies: Stirling engines, direct-fired combustion turbines, fuel cells, and biomass integrated gasification combined cycles. The report also discusses issues affecting India's rural electricity demand, including economic development, power reliability, and environmental concerns. The results of the costs of electricity comparison between the biomass DG systems and the coal-fired central grid station demonstrated that the DG technologies may be able to produce very competitively priced electricity by the start of the next century. The use of DG technology may provide a practical means of addressing many rural electricity issues that India will face in the future. Biomass DG technologies in particular offer unique advantages for the environment and for economic development that will make them especially attractive. 58 refs., 31 figs

  8. Regional differences in health, diet and weaning patterns amongst the first Neolithic farmers of central Europe.

    Science.gov (United States)

    Ash, Abigail; Francken, Michael; Pap, Ildikó; Tvrdý, Zdeněk; Wahl, Joachim; Pinhasi, Ron

    2016-01-01

    Across much of central Europe, the Linearbandkeramik (LBK) represents the first Neolithic communities. Arising in Transdanubia around 5500 cal. BC the LBK spread west to the Rhine within two to three hundred years, carrying elements of a mixed agricultural economy and a relatively homogeneous material culture. Colonisation of new regions during this progress would have required economic adaptations to varied ecological conditions within the landscape. This paper investigates whether such adaptation at a local scale affected health patterns and altered the dietary habits of populations that otherwise shared a common cultural and biological origin. Analysis of non-specific stress (linear enamel hypoplasia, porotic hyperostosis, cribra orbitalia) within five LBK populations from across central Europe in conjunction with published carbon and nitrogen stable isotope data from each site revealed a high prevalence of porotic hyperostosis and cribra orbitalia in western populations that was associated with a lower animal protein intake. Hypoplastic enamel was more frequently observed in eastern populations however, and may reflect geographic differences in childhood morbidity and mortality as a result of variation in social practices relating to weaning. Local socio-economic adaptations within the LBK were therefore an important factor in the exposure of populations to non-specific stress. PMID:27385276

  9. Interactions between zebrafish pigment cells responsible for the generation of Turing patterns.

    Science.gov (United States)

    Nakamasu, Akiko; Takahashi, Go; Kanbe, Akio; Kondo, Shigeru

    2009-05-26

    The reaction-diffusion system is one of the most studied nonlinear mechanisms that generate spatially periodic structures autonomous. On the basis of many mathematical studies using computer simulations, it is assumed that animal skin patterns are the most typical examples of the Turing pattern (stationary periodic pattern produced by the reaction-diffusion system). However, the mechanism underlying pattern formation remains unknown because the molecular or cellular basis of the phenomenon has yet to be identified. In this study, we identified the interaction network between the pigment cells of zebrafish, and showed that this interaction network possesses the properties necessary to form the Turing pattern. When the pigment cells in a restricted region were killed with laser treatment, new pigment cells developed to regenerate the striped pattern. We also found that the development and survival of the cells were influenced by the positioning of the surrounding cells. When melanophores and xanthophores were located at adjacent positions, these cells excluded one another. However, melanophores required a mass of xanthophores distributed in a more distant region for both differentiation and survival. Interestingly, the local effect of these cells is opposite to that of their effects long range. This relationship satisfies the necessary conditions required for stable pattern formation in the reaction-diffusion model. Simulation calculations for the deduced network generated wild-type pigment patterns as well as other mutant patterns. Our findings here allow further investigation of Turing pattern formation within the context of cell biology. PMID:19433782

  10. Structural pattern and ascent model in the Central Extremadura batholith, Hercynian belt, Spain

    Science.gov (United States)

    Castro, Antonio

    The Central Extremadura batholith constitutes an important alignment of plutonic rocks occupying part of the internal zones of the Iberian Hercynian belt. It comprises 13 plutons and numerous minor intrusions, and covers a wide compositional range from quartz-diorites to alkali-feldspar granites. Structural study of the individual plutons reveals that their internal structural patterns may be correlated. Correlation between the different structural patterns in the plutons and interpretation of the superimposed deformation in the metasedimentary host rocks indicate that the plutons were emplaced and deformed in an E-W, dextral, intracontinental shear zone developed during the second deformation phase (302-320 Ma). A qualitative ascent model has been established as follows: (1) development of extensional fractures at 45° to the E-W, dextral, shear zone; (2) intrusion of granitic magmas along these fractures and (3) rotation of the earlier intrusions, in a dextral sense, inducing antithetic shear zones (N-S sinistral) and a transverse shortening, perpendicular to the major axis of the earlier, deformed plutons as well as the forced emplacement of the later plutons.

  11. Plant diversity-productivity patterns in the alpine steppe environment of the Central Tianshan Mountains

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The biodiversity-productivity relationship is an important topic in the research of bio- diversity and ecosystem function. The plant diversity-productivity pattern is commonly unimodal and positively correlated. This paper researches the characteristics of plant diversity-productivity patterns in the Bayanbuluk alpine steppe in the central Tianshan Mountains, Xinjiang, China, and analyzes the effects of environmental factors on the distribution of plant communities, species composition, plant diversity and productivity in the steppe. The results show a positive correlation between plant diversity and productivity. DCCA (detrended canonical correspondence analysis) ordination reveals a significant relationship between the effects of air temperature, soil moisture content, available soil nitrogen, relative humidity and pH value on the distribution and composition of plant communities. There are significant correlations between the soil moisture content, relative humidity, pH value, air temperature and species richness and the aboveground biomass of Gramineae and Cyperaceae, and also significant correlations between the relative humidity, pH values and the total aboveground biomass of plant communities.

  12. Impact of resistant starch on body fat patterning and central appetite regulation.

    Directory of Open Access Journals (Sweden)

    Po-Wah So

    Full Text Available BACKGROUND: Adipose tissue patterning has a major influence on the risk of developing chronic disease. Environmental influences on both body fat patterning and appetite regulation are not fully understood. This study was performed to investigate the impact of resistant starch (RS on adipose tissue deposition and central regulation of appetite in mice. METHODOLOGY AND PRINCIPLE FINDINGS: Forty mice were randomised to a diet supplemented with either the high resistant starch (HRS, or the readily digestible starch (LRS. Using (1H magnetic resonance (MR methods, whole body adiposity, intrahepatocellular lipids (IHCL and intramyocellular lipids (IMCL were measured. Manganese-enhanced MRI (MEMRI was used to investigate neuronal activity in hypothalamic regions involved in appetite control when fed ad libitum. At the end of the interventional period, adipocytes were isolated from epididymal adipose tissue and fasting plasma collected for hormonal and adipokine measurement. Mice on the HRS and LRS diet had similar body weights although total body adiposity, subcutaneous and visceral fat, IHCL, plasma leptin, plasma adiponectin plasma insulin/glucose ratios was significantly greater in the latter group. Adipocytes isolated from the LRS group were significantly larger and had lower insulin-stimulated glucose uptake. MEMRI data obtained from the ventromedial and paraventricular hypothalamic nuclei suggests a satiating effect of the HRS diet despite a lower energy intake. CONCLUSION AND SIGNIFICANCE: Dietary RS significantly impacts on adipose tissue patterning, adipocyte morphology and metabolism, glucose and insulin metabolism, as well as affecting appetite regulation, supported by changes in neuronal activity in hypothalamic appetite regulation centres which are suggestive of satiation.

  13. Electric generator overhaul of the Ing. Carlos Ramirez Ulloa hydroelectric. Central project conclusions; Rehabilitacion de los generadores de la central hidroelectrica Ing. Carlos Ramirez Ulloa. Conclusiones del proyecto

    Energy Technology Data Exchange (ETDEWEB)

    Campuzano Martinez, Ignacio Roberto; Gonzalez Vazquez, Alejandro Esteban; Robles Pimentel, Edgar Guillermo; Esparza Saucedo, Marcos; Garcia Martinez, Javier; Sanchez Flores, Ernesto; Martinez Romero, Jose Luis [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1998-12-31

    The Hydroelectric Ing. Carlos Ramirez Ulloa Power Central has three 200 MW electric generators. The Central initiated its commercial operation in 1985. The electric generators had design problems that were properly corrected in an overhaul program that was initiated in 1996, with Unit 2 electric generator and completed in 1998 with Unit 1 electric generator. This paper presents the relevant aspects of the experience accumulated in the project. [Espanol] La central hidroelectrica Ing. Carlos Ramirez Ulloa cuenta con tres generadores de 200 MW cada uno. La central inicio su operacion comercial en 1985. Los generadores tenian problemas de diseno que fueron debidamente corregidos en un programa de rehabilitacion que inicio en 1996, con el generador de la unidad 2, y culmino en 1998 con el generador de la unidad 1. En este articulo se presentan los aspectos relevantes de la experiencia acumulada en el proyecto.

  14. A Novel Privacy Preserving Mining with Hybrid Pattern Mining and Key Generation

    OpenAIRE

    B. Ajit; C.P.V.N.J Mohan Rao; Sairam Vakkalanka

    2014-01-01

    Association rule mining over horizontal partitioning data is always an interesting research issue in the field of knowledge and data engineering. Data holder forwards the data sets to centralized server, privacy can be maintained by security protocols, and our security protocol communicates in terms of subsets from both the data holders and player as ingredients for secure transmission. Association rules can be generated at centralized server efficiently. In this paper we are proposing a priv...

  15. Commercialization of new energy technologies. Appendix A. Case study 1: central station electric power generation technologies

    International Nuclear Information System (INIS)

    The results of a survey on Technologies for Central Power Generation are presented. The central power generation technologies selected for consideration were: fusion; breeder reactors; solar electric (thermal); geothermal; and magnetohydrodynamics. The responses of industry executives who make key investment decisions concerning new energy technologies and who to identify the problems faced in the development and commercialization of new energy systems are presented. Evaluation of these responses led to the following recommendations: increase industry input into the R, D and D planning process; establish and advocate priorities for new technologies based on detailed analysis of a technology's value in terms of overall national goals; create a mechanism for a joint ERDA/industry appraisal of priorities and programs; increase level of federal funding or subsidy of new technology demonstrations; and focus the activities of the national laboratories on basic research and very early product development; and emphasize industry involvement in systems development

  16. Generating power stations and optimization energetic of processes; Centrales generadoras y optimacion energetica de procesos

    Energy Technology Data Exchange (ETDEWEB)

    Gutierrez Ramirez, Ranulfo; Fernandez Montiel, Manuel Francisco [Instituto de Investigaciones Electricas, Temixco, Morelos (Mexico)

    1999-07-01

    Some recent experiences of the Management of Thermal Processes of the Instituto de Investigaciones Electricas (IIE) related to the works on generating power stations of electricity, plants of cogeneration and energy saving are presented. [Spanish] Se presentan algunas experiencias recientes de la Gerencia de Procesos Termicos del Instituto de Investigaciones Electricas (IIE) relacionadas con los trabajos sobre centrales generadoras de electricidad, plantas de cogeneracion y ahorro de energia.

  17. Fluid power network for centralized electricity generation in offshore wind farms

    OpenAIRE

    Jarquin-Laguna, A.

    2014-01-01

    An innovative and completely different wind-energy conversion system is studied where a centralized electricity generation within a wind farm is proposed by means of a hydraulic network. This paper presents the dynamic interaction of two turbines when they are coupled to the same hydraulic network. Due to the stochastic nature of the wind and wake interaction effects between turbines, the operating parameters (i.e. pitch angle, rotor speed) of each turbine are different. Time domain simulatio...

  18. [Distribution patterns of wild felids (Carnivora: Felidae) in the dry tropics of Central-Western Mexico].

    Science.gov (United States)

    Charre-Medellín, Juan Felipe; Monterrubio-Rico, Tiberio Cesar; Guido-Lemus, Daniel; Mendoza, Eduardo

    2015-09-01

    The Michoacán state is characterized by the existence of important environmental heterogeneity in terms of climate, topography and types of vegetation, which includes the worldwide endangered tropical dry forest. Some reports indicating the presence of the six species of felids occurring in Mexico in this region have been made; however, evidence to support these reports is scant, and filling this lack of information is particularly critical in the case of threatened species or habitats. The aim of this study was to systematize and analyze data distribution patterns of felids in the state of Michoacán, in the Central-Western Mexico. We conducted a review of literature and databases to compile species presence records in the study region. Moreover, we analyzed data obtained from ten years of field work conducted in the region, in which complementary methods (detection of direct and indirect evidence of species occurrence along transects, camera-trapping and interviews to local people) were applied to detect the presence of felid species. We compiled a total of 29 presence records of felids in the region from our review. Additionally, field work, which accumulated 1,107.5 km of walked transects, and 8 699 camera-trap days, produced 672 records of species presence. Lynx rufus was the species with the lowest number of records and the most restricted distribution. In contrast, the species with the greatest number of records was Leoparduspardalis (n = 343). In general, 89% of felids records occurred below 1,000 masl. Overall mean annual temperature of presence records was 24 °C and mean annual precipitation was 1,040 mm. The species whose presence records showed the most distinctive pattern, in terms of temperature and precipitation associated, was L. rufus (15.8 ± 1.3°C and 941 ± 171 mm). Results of a cluster analysis showed that areas supporting different combinations of eco-regions and types of vegetation could be grouped in five clusters having different

  19. Pigment cell movement is not required for generation of Turing patterns in zebrafish skin

    Science.gov (United States)

    Bullara, D.; De Decker, Y.

    2015-01-01

    The zebrafish is a model organism for pattern formation in vertebrates. Understanding what drives the formation of its coloured skin motifs could reveal pivotal to comprehend the mechanisms behind morphogenesis. The motifs look and behave like reaction–diffusion Turing patterns, but the nature of the underlying physico-chemical processes is very different, and the origin of the patterns is still unclear. Here we propose a minimal model for such pattern formation based on a regulatory mechanism deduced from experimental observations. This model is able to produce patterns with intrinsic wavelength, closely resembling the experimental ones. We mathematically prove that their origin is a Turing bifurcation occurring despite the absence of cell motion, through an effect that we call differential growth. This mechanism is qualitatively different from the reaction–diffusion originally proposed by Turing, although they both generate the short-range activation and the long-range inhibition required to form Turing patterns. PMID:25959141

  20. On-Shore Central Hydraulic Power Generation for Wind and Tidal Energy

    Science.gov (United States)

    Jones, Jack A.; Bruce, Allan; Lim, Steven; Murray, Luke; Armstrong, Richard; Kimbrall, Richard; Cook-Chenault, Kimberly; DeGennaro, Sean

    2012-01-01

    Tidal energy, offshore wind energy, and onshore wind energy can be converted to electricity at a central ground location by means of converting their respective energies into high-pressure hydraulic flows that are transmitted to a system of generators by high-pressure pipelines. The high-pressure flows are then efficiently converted to electricity by a central power plant, and the low-pressure outlet flow is returned. The Department of Energy (DOE) is presently supporting a project led by Sunlight Photonics to demonstrate a 15 kW tidal hydraulic power generation system in the laboratory and possibly later submerged in the ocean. All gears and submerged electronics are completely eliminated. A second portion of this DOE project involves sizing and costing a 15 MW tidal energy system for a commercial tidal energy plant. For this task, Atlantis Resources Corporation s 18-m diameter demonstrated tidal blades are rated to operate in a nominal 2.6 m/sec tidal flow to produce approximately one MW per set of tidal blades. Fifteen units would be submerged in a deep tidal area, such as in Maine s Western Passage. All would be connected to a high-pressure (20 MPa, 2900 psi) line that is 35 cm ID. The high-pressure HEPG fluid flow is transported 500-m to on-shore hydraulic generators. HEPG is an environmentally-friendly, biodegradable, watermiscible fluid. Hydraulic adaptations to ORPC s cross-flow turbines are also discussed. For 15 MW of wind energy that is onshore or offshore, a gearless, high efficiency, radial piston pump can replace each set of top-mounted gear-generators. The fluid is then pumped to a central, easily serviceable generator location. Total hydraulic/electrical efficiency is 0.81 at full rated wind or tidal velocities and increases to 0.86 at 1/3 rated velocities.

  1. Post-release survival and movements patterns of roosterfish (Nematistius pectoralis off the Central American coastline

    Directory of Open Access Journals (Sweden)

    Chugey A Sepulveda

    2015-03-01

    Full Text Available Acoustic telemetry was used to assess immediate post-release survival and track the short-term movement patterns of roosterfish Nematistius pectoralis between 2008 and 2010. Seven roosterfish (85 to 146 cm fork length, FL were continuously tracked along the Central American coastline for periods of up to 28 h following capture on recreational fishing tackle. All seven roosterfish were initially captured and spent the duration of the track period proximal to the coastline in waters <100 m of depth. From depth records and horizontal movements, it was determined that all seven roosterfish survived the acute effects of capture. The greatest depth achieved by any of the tracked individuals was 62 m and collectively roosterfish spent over 90% of the track records between the surface and 12 m. For all tracks, fish size showed no effect on maximum or average dive depth and the average day (7 ± 2 m and night (6 ± 2 m depths were similar among individuals. Mean water temperature for all tracks was 28 ± 1°C, with the lowest temperature experienced at depth being 23°C. Total horizontal movements from the roosterfish in this study ranged from 14.7 to 42.2 km and averaged 1.5 ± 0.4 km h-1. Data on movements in relation to bathymetry, prey presence and habitat structure are discussed. Collectively, these data provide insight into the immediate post-release disposition and short-term movements of this poorly studied species along the coast of Central America.

  2. Mediterranean climate patterns and wine quality in North and Central Italy.

    Science.gov (United States)

    Dalu, John David; Baldi, Marina; Marta, Anna Dalla; Orlandini, Simone; Maracchi, Gianpiero; Dalu, Giovanni; Grifoni, Daniele; Mancini, Marco

    2013-09-01

    Results show that the year-to-year quality variation of wines produced in North and Central Italy depends on the large-scale climate variability, and that the wine quality improvement in the last four decades is partially due to an increase of temperature and to a decrease of precipitation in West and Central Mediterranean Europe (WME; CME). In addition, wine quality is positively correlated with air temperature throughout the entire active period of the grapevine, weakly negatively correlated with precipitation in spring, and well negatively correlated in summer and fall. The month-to-month composites of the NAO anomaly show that, in years of good quality wine, this anomaly is negative in late spring, oscillates around zero in summer, and is positive in early fall; while, in years of bad quality wine, it is positive in late spring and summer, and negative in early fall, i.e. its polarity has an opposite sign in spring and fall in good versus bad years. The composite seasonal maps show that good wines are produced when the spring jet stream over the Atlantic diverts most of the weather perturbations towards North Europe, still providing a sufficient amount of rainwater to CME; when summer warming induced by southerly winds is balanced by the cooling induced by westerly winds; and when a positive geopotential anomaly over WME shelters CME from fall Atlantic storms. Bad quality wines are produced when the jet stream favors the intrusion of the Atlantic weather perturbations into the Mediterranean. Results suggest that atmospheric pattern persistencies can be used as precursors for wine quality forecast. PMID:23152193

  3. Long-term landscape patterns of past fire events in a montane ponderosa pine forest of central Colorado

    OpenAIRE

    Brown, P. M.; Kaufmann, M. R.; Sheppard, W. D.

    1999-01-01

    Parameters of fire regimes, including fire frequency, spatial extent of burned areas, fire severity, and season of fire occurrence, influence vegetation patterns over multiple scales. In this study, centuries-long patterns of fire events in a montane ponderosa pine – Douglas-fir forest landscape surrounding Cheesman Lake in central Colorado were reconstructed from fire-scarred trees and inferences from forest stand ages. We crossdated 153 fire-scarred trees from an approximately 4000 ha study...

  4. Auto-Pattern Programmable Kernel Filter (Auto-PPKF for Suppression of Bot Generated Traffic

    Directory of Open Access Journals (Sweden)

    Kritika Govind

    2013-11-01

    Full Text Available Bots usually vary from their other malicious counter parts by periodically reporting to the botmaster through regular exchange of messages. Our experiments on bot attack generation showed a continuous exchange of packets with similar content between the botmaster and the zombie machine at various time intervals. Though there were also genuine packets with similar content being sent out of the victim machine challenge was to differentiate between the two and pass only the genuine ones. In this paper, an algorithm namely Auto-Pattern Programmable Kernel Filter (Auto-PPKF, for automatic detection of patterns from packet payload for filtering out malicious packets generated by bots is proposed. The significant feature of our proposed Auto-PPKF algorithm is that, the malicious pattern is deduced at kernel level on the fly from packet payload. Traditional algorithms such as Boyer Moore, Knuth Morris Patt, and Naive Pattern search algorithms require the pattern to be identified available a priori. Currently, Longest Common Subsequence (LCS algorithm stands as the most preferred algorithm for pattern matching. But the disadvantage is that common sequences can also exist in many genuine packets. Hence, the challenge lies in automatic detection of malicious patterns and filtering of the packets having such malicious patterns. This would not only put off the communication between the Botmaster and Zombie machine, but will also thus prevent user information from being sent to the botmaster.

  5. Semi-arid Vegetation Pattern, Stability and Suitability to Suppress Sand Movement in Central Sudan

    Directory of Open Access Journals (Sweden)

    N.K.N. Al-Amin

    2011-01-01

    Full Text Available Moving sand that threatens Gezira scheme is the dominant land degradation feature in central Sudan and the front line defence is the sparse scattered natural vegetation of the area. The study aimed to assess the role of this vegetation to suppress drifting sand and to monitor their ability to face the impact of climate change and human activity (deforestation. The dimensions of the sand captured by single tree of dominant species, Acacia tortilis, Leptadenia pyrotechnica, Prosopis juliflora and Panicum turgidum were measured and the volumes were calculated. To picture the drought pattern 5-year running means of annual rainfalls (1941-2007 of the study area were calculated and compared with long-term mean. Deforestation was indicated by local community wood consumption in relation to the average woody biomass (in good condition. The results show that scattered trees of the right densities had potentiality to settle drifting sand, but they were subjected to 20 years dry seasons followed by only 4 wet years and now are subjected to a new era of dry spell. This condition is not in favour of the semi-arid vegetation pattern sustainability and a suitable measure to enhance natural regeneration is needed. In addition, the community's wood demand was higher than the resource, where a person would destroy 0.5 ha/year compared to 0.9 ha/year per person available reveals the magnitude of deforestation. Encouragement of farmers to use alternative energy sources and functional application of laws and regulations to protect the existing vegetation rem ain crucial.

  6. Simultaneous detection of both GDNF and GFRα1 expression patterns in the mouse central nervous system

    Directory of Open Access Journals (Sweden)

    Clara Ortega-de San Luis

    2016-06-01

    Full Text Available Glial cell line-derived neurotrophic factor (GDNF is proposed as a therapeutic tool in Parkinson’s disease, addiction-related disorders, and neurodegenerative conditions affecting motor neurons. Despite the high amount of work about GDNF therapeutic application, the neuronal circuits requiring GDNF trophic support in the brain and spinal cord are poorly characterized. Here, we defined GDNF and GDNF family receptor-α 1 (GFRα1 expression pattern in the brain and spinal cord of newborn and adult mice. We performed systematic and simultaneous detection of EGFP and LacZ expressing alleles in reporter mice and asked whether modifications of this signaling pathway lead to a significant central nervous system (CNS alteration. GFRα1 was predominantly expressed by neurons but also by an unexpected population of non-neuronal cells. GFRα1 expression pattern was wider in neonatal than in adult CNS and GDNF expression was restricted in comparison with GFRα1 at both developmental time points. The use of confocal microscopy to imaging X-gal deposits and EGFP allowed us to identify regions containing cells that expressed both proteins and to discriminate between auto and non-autotrophic signaling. We also suggested long-range GDNF-GFRα1 circuits taking advantage of the ability of the EGFP genetically encoded reporter to label long distance projecting axons. The complete elimination of either the ligand or the receptor during development did not produce major abnormalities, suggesting a preponderant role for GDNF signaling during adulthood. In the spinal cord, our results pointed to local modulatory interneurons as the main target of GDNF produced by Clarke’s column cells. Our work increases the understanding on how GDNF signals in the CNS and establish a crucial framework for posterior studies addressing either the biological role of GDNF or the optimization of trophic factor-based therapies.

  7. High-fidelity spherical cholesteric liquid crystal Bragg reflectors generating unclonable patterns for secure authentication

    Science.gov (United States)

    Geng, Yong; Noh, JungHyun; Drevensek-Olenik, Irena; Rupp, Romano; Lenzini, Gabriele; Lagerwall, Jan P. F.

    2016-01-01

    Monodisperse cholesteric liquid crystal microspheres exhibit spherically symmetric Bragg reflection, generating, via photonic cross communication, dynamically tuneable multi-coloured patterns. These patterns, uniquely defined by the particular sphere arrangement, could render cholesteric microspheres very useful in countless security applications, as tags to identify and authenticate their carriers, mainly physical objects or persons. However, the optical quality of the cholesteric droplets studied so far is unsatisfactory, especially after polymerisation, a step required for obtaining durable samples that can be used for object identification. We show that a transition from droplets to shells solves all key problems, giving rise to sharp patterns and excellent optical quality even after polymerisation, the polymerised shells sustaining considerable mechanical deformation. Moreover, we demonstrate that, counter to prior expectation, cross communication takes place even between non-identical shells. This opens additional communication channels that add significantly to the complexity and unique character of the generated patterns. PMID:27230944

  8. High-fidelity spherical cholesteric liquid crystal Bragg reflectors generating unclonable patterns for secure authentication

    Science.gov (United States)

    Geng, Yong; Noh, Junghyun; Drevensek-Olenik, Irena; Rupp, Romano; Lenzini, Gabriele; Lagerwall, Jan P. F.

    2016-05-01

    Monodisperse cholesteric liquid crystal microspheres exhibit spherically symmetric Bragg reflection, generating, via photonic cross communication, dynamically tuneable multi-coloured patterns. These patterns, uniquely defined by the particular sphere arrangement, could render cholesteric microspheres very useful in countless security applications, as tags to identify and authenticate their carriers, mainly physical objects or persons. However, the optical quality of the cholesteric droplets studied so far is unsatisfactory, especially after polymerisation, a step required for obtaining durable samples that can be used for object identification. We show that a transition from droplets to shells solves all key problems, giving rise to sharp patterns and excellent optical quality even after polymerisation, the polymerised shells sustaining considerable mechanical deformation. Moreover, we demonstrate that, counter to prior expectation, cross communication takes place even between non-identical shells. This opens additional communication channels that add significantly to the complexity and unique character of the generated patterns.

  9. Patterns of mercury dispersion from local and regional emission sources, rural Central Wisconsin, USA

    Directory of Open Access Journals (Sweden)

    A. Kolker

    2010-01-01

    Full Text Available Simultaneous real-time changes in mercury (Hg speciation – reactive gaseous Hg (RGM, elemental Hg (Hg°, and fine particulate Hg (Hg-PM2.5, were determined from June to November 2007, in ambient air at three locations in rural Central Wisconsin. Known Hg emission sources within the airshed of the monitoring sites include: 1 a 1114 megawatt (MW coal-fired electric utility generating station; 2 a Hg-bed chlor-alkali plant; and 3 a smaller (465 MW coal-burning electric utility. Monitoring sites, showing sporadic elevation of RGM, Hg° and Hg-PM2.5, were positioned at distances of 25, 50 and 100 km northward of the larger electric utility. A series of RGM events were recorded at each site. The largest, on 23 September, occurred under prevailing southerly winds, with a maximum RGM value (56.8 pg m−3 measured at the 100 km site, and corresponding elevated SO2 (10.41 ppbv; measured at 50 km site. The finding that RGM, Hg°, and Hg-PM2.5 are not always highest at the 25 km site, closest to the large generating station, contradicts the idea that RGM decreases with distance from a large point source. This may be explained if: 1 the 100 km site was influenced by emissions from the chlor-alkali facility or by RGM from regional urban sources; 2 the emission stack height of the larger power plant promoted plume transport at an elevation where the Hg is carried over the closest site; or 3 RGM was being generated in the plume through oxidation of Hg°. Operational changes at each emitter since 2007 should reduce their Hg output, potentially allowing quantification of the environmental benefit in future studies.

  10. Use of a relational reinforcement learning algorithm to generate dynamic activity-travel patterns

    OpenAIRE

    VANHULSEL, Marlies; Janssens, Davy; Wets, Geert

    2007-01-01

    In the course of the past decade activity-based models have entered the area of transportation modelling. Such models simulate the generation of individual activity-travel patterns while deciding simultaneously on the different dimensions of activity-travel behaviour, such as the type of activity, the activity location, the transport mode used to reach this location, the starting time and duration of the activity, etc. However, as real-world activity-travel patterns prove not to be static due...

  11. Towards a Pattern-based Automatic Generation of Logical Specifications for Software Models

    OpenAIRE

    Klimek, Radoslaw

    2014-01-01

    The work relates to the automatic generation of logical specifications, considered as sets of temporal logic formulas, extracted directly from developed software models. The extraction process is based on the assumption that the whole developed model is structured using only predefined workflow patterns. A method of automatic transformation of workflow patterns to logical specifications is proposed. Applying the presented concepts enables bridging the gap between the benefits of deductive rea...

  12. A Walking Pattern Generation Method for Humanoid Robots Using Least Square Method and Quartic Polynomial

    OpenAIRE

    Hong, Seokmin; Oh, Yonghwan; Chang, Young-Hwan; You, Bum-Jae

    2009-01-01

    This paper proposed a new walking pattern method for the humanoid robot. The propose method was based on the linear inverted pendulum model as the simple model of humanoid robot. And this method consisted of three step modules for generating walking pattern. Using these step modules, this paper addressed robustness of the proposed method against initial values of the ZMP and CoM, and validated the efficiency with the slope at the single support phase through simulations. And finally we showed...

  13. Morphotectonic analysis, structural evolution/pattern of a contractional ridge: Giouchtas Mt., Central Crete, Greece

    Indian Academy of Sciences (India)

    Kokinou Eleni; Skilodimou Hariklia D; Bathrellos George D; Antonarakou Assimina; Kamberis Evangelos

    2015-04-01

    The Giouchtas Mountain is situated south of Heraklion, Central Crete. It is a N–S trending morphological asymmetric ridge with a steep western slope, whilst its eastern slope is characterized by a smoother relief, composed of Mesozoic limestone and Eocene–lower Oligocene flysch of the Gavrovo–Tripolis zone. The present study focusses on the structural pattern and development of Giouchtas Mountain. Morphotectonic analyses in combination with field mapping and tectonic analysis were performed for this purpose. GIS techniques were used for mapping the spatial distribution of the geological features on the topographic relief of the area. Geomorphic indices, used in the present study, are the mountain front sinuosity index (Smf) and the valley floor/width ratio index (Vf). Based on Smf and Vf values, it is implied that this area can be assigned to a tectonic class I, corresponding to higher tectonic activity. However, spatial variations of the tectonic activity along the segmented fronts point to a general trend of increasing activity towards the north and especially, northeast. The model of this possibly active structural feature corresponds to a compressional mechanism followed by an earliest Mid. Miocene to Holocene late-stage deformation related to extensional faulting.

  14. Socio-Economic Factors Affecting Home Internet Usage Patterns in Central Queensland

    Directory of Open Access Journals (Sweden)

    Wal J. Taylor

    2003-01-01

    Full Text Available Governments and other policy makers are concerned with the gap in home Internet usage between people from metropolitan and rural areas. A survey conducted in Central Queensland, Australia examined differences in home Internet usage patterns between young and old, male and female, people in urban and rural areas, married and unmarried, well-educated and less educated, rich and poor, and employed and unemployed and found significant differences. These results highlight areas for further research and provide a basis for government agencies and industries to consider these associations in future policy formulation for regional development using ICT. The research suggested that further research should be conducted to monitor consuming behaviors of the youngest age group in Internet use for entertainment and information search in order to detect possible Internet overuse or addiction. In addition, further research should be conducted to find out what people search for on the Internet, and if for employment opportunities, financial incentives are suggested for the unemployed people.

  15. Land use patterns and the risk of West Nile virus transmission in central Illinois.

    Science.gov (United States)

    Gardner, Allison M; Lampman, Richard L; Muturi, Ephantus J

    2014-05-01

    Understanding how human land use patterns influence mosquito ecology and the risk of mosquito-borne pathogens is critical for the development of disease management strategies. We examined how different environments influenced mosquito species composition, abundance, and West Nile virus (WNV) infection rates in central Illinois. Using a combination of gravid traps and CDC light traps, adult mosquitoes were collected every other week from June 24 to September 16, 2012, in four major land use categories-row crops, prairies, forest fragments, and residential neighborhoods. The mosquitoes were identified to species morphologically, and pools of pure and mixed Culex mosquitoes (primarily Culex pipiens and Culex restuans) were tested for WNV-RNA by qRT-PCR. Mosquito species diversity was significantly higher in forest habitats compared to residential, agricultural, and prairie land use categories. All the four landscape types were equally important habitats for WNV vectors Cx. pipiens and Cx. restuans, contrary to previous findings that these species principally inhabit the residential areas. WNV-infected mosquito pools were observed in all land use types, and the infection rates overlapped among land use categories. Although our findings support the importance of residential habitats for WNV transmission to humans, they also establish that prairie, row crops, and wood lots are potentially important refuges for enzootic transmission. This is particularly important in urban ecosystems where these land use categories are small, interspersed fragments serving as potential refuge sites during periods of low rainfall. PMID:24746038

  16. Deleterious Emission Abatement through Structured Energy Use Pattern: A North Central Nigeria Perspective

    Science.gov (United States)

    Ajayi-Banji, Ademola; Omotosho, Olayinka; Amori, Anthony; Alao, Damilola; Igbode, Imoisime; Abimbola, Olufemi

    2016-05-01

    Holistic view of household energy consumption based on greenhouse gas emissions in the North Central cities of Nigeria was examined in this study. Scenarios considered were based on income level of energy users (low and high) and energy metering system (i.e. pre-paid and post-paid energy billing systems). Strong direct nexus was observed between energy use and emissions pattern. Energy utilization by post-paid category had higher weekly average value of 35.09 and 41.70 kWh as against 23.18 and 33.38 kWh for low and high income pre-paid consumers respectively. Energy use and greenhouse gas emissions from both classification followed similar trend. Data obtained and analysed in the study show that global warming and acidification potentials could be reduced by 33.94 and 19.95 % for low and high income category consumers when pre-paid meters are in place. Conclusively, energy system users with pre-paid metering system displayed reasonable level of management decisions that reduce energy wastage and consequently environmental negative impacts.

  17. When does colonisation of a semi-arid hillslope generate vegetation patterns?

    Science.gov (United States)

    Sherratt, Jonathan A

    2016-07-01

    Patterned vegetation occurs in many semi-arid regions of the world. Most previous studies have assumed that patterns form from a starting point of uniform vegetation, for example as a response to a decrease in mean annual rainfall. However an alternative possibility is that patterns are generated when bare ground is colonised. This paper investigates the conditions under which colonisation leads to patterning on sloping ground. The slope gradient plays an important role because of the downhill flow of rainwater. One long-established consequence of this is that patterns are organised into stripes running parallel to the contours; such patterns are known as banded vegetation or tiger bush. This paper shows that the slope also has an important effect on colonisation, since the uphill and downhill edges of an isolated vegetation patch have different dynamics. For the much-used Klausmeier model for semi-arid vegetation, the author shows that without a term representing water diffusion, colonisation always generates uniform vegetation rather than a pattern. However the combination of a sufficiently large water diffusion term and a sufficiently low slope gradient does lead to colonisation-induced patterning. The author goes on to consider colonisation in the Rietkerk model, which is also in widespread use: the same conclusions apply for this model provided that a small threshold is imposed on vegetation biomass, below which plant growth is set to zero. Since the two models are quite different mathematically, this suggests that the predictions are a consequence of the basic underlying assumption of water redistribution as the pattern generation mechanism. PMID:26547308

  18. Assessing incentive policies for integrating centralized solar power generation in the Brazilian electric power system

    International Nuclear Information System (INIS)

    This study assesses the impacts of promoting, through auctions, centralized solar power generation (concentrated solar power – CSP, and photovoltaic solar panels – PV) on the Brazilian power system. Four types of CSP plants with parabolic troughs were simulated at two sites, Bom Jesus da Lapa and Campo Grande, and PV plants were simulated at two other sites, Recife and Rio de Janeiro. The main parameters obtained for each plant were expanded to other suitable sites in the country (totaling 17.2 GW in 2040), as inputs in an optimization model for evaluating the impacts of the introduction of centralized solar power on the expansion of the electricity grid up to 2040. This scenario would be about USD$ 185 billion more expensive than a business as usual scenario, where expansion solely relies on least-cost options. Hence, for the country to incentivize the expansion of centralized solar power, specific auctions for solar energy should be adopted, as well as complementary policies to promote investments in R and D and the use of hybrid systems based on solar and fuels in CSP plants. - Highlights: • We assess the impacts of promoting centralized CSP and PV by auctions in Brazil. • We simulate energy scenarios with and without solar power. • Our solar scenario leads to 17 GW of solar capacity installed between 2020 and 2040. • This solar scenario is some USD$ 185 billion more expensive than the base case

  19. Design, fabrication, and evaluation of diffractive optical elements for generation of focused ring patterns

    Science.gov (United States)

    Vijayakumar, A.; Bhattacharya, Shanti

    2015-02-01

    Focused ring patterns are used for many applications like corneal surgery, micro drilling, optical trapping, etc. The generation of focused ring patterns in the earlier reported cases employed many refractive optical components with different functions. As a result the optics configurations of the ring pattern generation systems are bulkier. In diffractive optics, it is possible to alter a function of an element and also integrate multiple functions in a single element. In this paper, we present the design, fabrication and evaluation of single and composite diffractive optical elements for the generation of focused ring patterns. A diffractive toric Fresnel zone lens was designed for parallel beam illumination. This element is compared with other composite diffractive elements capable of generating focused ring patterns. The toric Fresnel zone lens and composite elements were fabricated using electron beam direct writing. The fabricated elements were found to exhibit interesting properties, with the toric lens out-performing the other elements in several areas such as efficiency, focal depth, and ring thickness.

  20. Micromachining of amplitude and phase modulated reflective computer generated hologram patterns in silicon

    Energy Technology Data Exchange (ETDEWEB)

    Ow, Y.S., E-mail: g0601170@nus.edu.s [Physics Department, National University of Singapore, Lower Kent Ridge Road, Singapore 119260 (Singapore); Breese, M.B.H.; Leng, Y.R.; Azimi, S.; Teo, E.J. [Physics Department, National University of Singapore, Lower Kent Ridge Road, Singapore 119260 (Singapore); Sun, X.W. [School of Electrical and Electronic Engineering, Nanyang Technological University, Nanyang Avenue, Singapore 639798 (Singapore)

    2010-05-01

    Silicon has been machined on lateral resolutions of micrometers and on depth resolutions of nanometers using a recently-developed process based on ion irradiation and electrochemical anodisation. Here we investigate its use as a recording medium for computer generated hologram patterns. We describe the fabrication of both amplitude and phase binary modulated reflective computer generated hologram patterns on a silicon surface with pixel sizes of 5 mum. We further discuss the use of micromachined silicon to variably modulate both amplitude and phase in a continuous, rather than a binary fashion.

  1. A low cost high resolution pattern generator for electron-beam lithography

    International Nuclear Information System (INIS)

    A simple, very low cost pattern generator for electron-beam lithography is presented. When it is applied to a scanning electron microscope, the system allows a high precision positioning of the beam for lithography of very small structures. Patterns are generated by a suitable software implemented on a personal computer, by using very simple functions, allowing an easy development of new writing strategies for a great adaptability to different user necessities. Hardware solutions, as optocouplers and battery supply, have been implemented for reduction of noise and disturbs on the voltages controlling the positioning of the beam

  2. Calculation of second-harmonic wave pattern generated by focused cylindrical vector beams

    Science.gov (United States)

    Ohtsu, A.; Kozawa, Y.; Sato, S.

    2010-03-01

    We calculated the second-harmonic wave pattern induced by focused cylindrically symmetric, polarized vector beams. The second-order nonlinear polarization was expressed for fundamental electric field components passed through a dielectric interface based on vector diffraction theory. Furthermore, the second-harmonic wave pattern was represented on the basis of the far-field approximate expression derived from the formulation of higher-order harmonic generation including a Green's function. For a (110) zinc selenide crystal, the calculated forward emission patterns of the second-harmonic wave were eight-figure shaped as observed in experiment.

  3. Implementation of a Data Packet Generator Using Pattern Matching for Wearable ECG Monitoring Systems

    OpenAIRE

    Yun Hong Noh; Do Un Jeong

    2014-01-01

    In this paper, a packet generator using a pattern matching algorithm for real-time abnormal heartbeat detection is proposed. The packet generator creates a very small data packet which conveys sufficient crucial information for health condition analysis. The data packet envelopes real time ECG signals and transmits them to a smartphone via Bluetooth. An Android application was developed specifically to decode the packet and extract ECG information for health condition analysis. Several graphi...

  4. The central electricity generating board approach to low level waste activity assessment

    International Nuclear Information System (INIS)

    Assessment of the activity of low level waste (LLW) within Central Electricity Generating Board (CEGB) has historically been achieved by a combination of dose rate measurements and empirical isotopic composition data. Because of changes in regulatory requirements and the increased costs of disposal, it became clear in 1986/87 that fundamental changes in the method of assay of LLW were needed. This paper describes the approach adopted by CEGB to introduce these changes. Details of the philosophy of 'area fingerprints' and the programme of work for their determination are outlined together with a description of an on-site monitoring system which represents a practical implementation of the approach

  5. Czech alien flora and the historical pattern of its formation: what came first to Central Europe?

    Science.gov (United States)

    Pysek, Petr; Sádlo, Jirí; Mandák, Bohumil; Jarosík, Vojtech

    2003-03-01

    Temporal patterns of immigration to the country were analysed using 668 alien species in the flora of the Czech Republic for which the dates of the first record were available (64.8% of the total number of 1031 so-called neophytes, i.e. aliens introduced after the year 1500). After a period of initial slow increase lasting to the 1840s, the accumulation of neophytes over time could be best fitted by a linear model that explained 97% of the variance. The intensity of floristic research, which varied between periods, did not significantly affect the overall increase in the number of aliens. The effect of species traits on the year of introduction was evaluated, with continent of origin, introduction type (deliberate or accidental), life history, Grime's life strategy, onset of flowering, mode of dispersal and propagule size as explanatory variables. Species of European origin and CSR strategists arrived earlier than those with other origins and strategies. Deliberately introduced species appeared earlier than accidental arrivals, and those cultivated for utilitary reasons on average arrived earlier than ornamentals. Species capable of early flowering were remarkably more prevalent among early newcomers. A separate analysis of accidentally introduced American species also identified life history as a significant predictor of immigration time, with annuals being introduced earlier than biennials and perennials. The data contribute to an understanding of a crucial stage of the invasion process that has received little attention in the literature. The model "early alien" to Central Europe is a European species with a CSR strategy deliberately brought for cultivation as a utilitary plant. Once it escaped from cultivation, its establishment in the wild was favoured by its ability to flower early and, therefore, complete the life cycle. PMID:12647111

  6. Student-Generated Content in College Teaching: Content Quality, Behavioural Pattern and Learning Performance

    Science.gov (United States)

    Yang, X.; Guo, X.; Yu, S.

    2016-01-01

    This study investigates the quality of course content, behavioural patterns of students and learning performance in teaching of student-generated content (SGC). A total of 49 third-year university students in educational technology participated in this study. By combining the methods of questionnaire, lag sequence analysis and interview, the study…

  7. Pattern-generating travelling waves in a discrete multicellular system with lateral inhibition

    Science.gov (United States)

    Plahte, Erik; Øyehaug, Leiv

    2007-02-01

    On a one-dimensional string of cells, the juxtacrine signalling model for Delta-Notch lateral inhibition by Collier et al. [J.R. Collier, N.A.M. Monk, P.K. Maini, J.H. Lewis, Pattern formation by lateral inhibition with feedback: A mathematical model of Delta-Notch intercellular interaction, J. Theoret. Biol. 183 (1996) 429-446] exhibits a predominant alternating pattern of cells expressing either Delta or Notch, as well as many aperiodic patterns. Despite this multistationarity, in the idealised situation of no noise, travelling waves invading the unstable, homogeneous state only generate the predominant alternating pattern in their wake all over the lattice. However, this robustness is totally lost in the presence of stochastic noise because the invaded, initial state is unstable. Using linear approximations around the initial, homogeneous state and around the final, patterned state, we are able to derive analytically all essential properties of the wave: the shape of the wave front, the unique, alternating pattern generated by the wave, and the asymptotic speed of the wave front. We show that the asymptotic wave speed equals the theoretical minimum wave speed. The latter agrees extremely well with the value estimated from numerical simulations. Thus, in this system travelling waves are pulled by the leading edge of the front.

  8. Directivity patterns of laser-generated sound in solids: Effects of optical and thermal parameters.

    Science.gov (United States)

    Krylov, Victor V

    2016-07-01

    In the present paper, directivity patterns of laser-generated sound in solids are investigated theoretically. Two main approaches to the calculation of directivity patterns of laser-generated sound are discussed for the most important case of thermo-optical regime of generation. The first approach, which is widely used in practice, is based on the simple modelling of the equivalent thermo-optical source as a mechanical dipole comprising two horizontal forces applied to the surface in opposite directions. The second approach is based on the rigorous theory that takes into account all acoustical, optical and thermal parameters of a solid material and all geometrical and physical parameters of a laser beam. Directivity patterns of laser-generated bulk longitudinal and shear elastic waves, as well as the amplitudes of generated Rayleigh surface waves, are calculated for different values of physical and geometrical parameters and compared with the directivity patterns calculated in case of dipole-source representation. It is demonstrated that the simple approach using a dipole-source representation of laser-generated sound is rather limited, especially for description of generated longitudinal acoustic waves. A practical criterion is established to define the conditions under which the dipole-source representation gives predictions with acceptable errors. It is shown that, for radiation in the normal direction to the surface, the amplitudes of longitudinal waves are especially sensitive to the values of thermal parameters and of the acoustic reflection coefficient from a free solid surface. A discussion is given on the possibility of using such a high sensitivity to the values of the reflection coefficient for investigation of surface properties of real solids. PMID:26851995

  9. Patterns of mercury dispersion from local and regional emission sources, rural Central Wisconsin, USA

    Directory of Open Access Journals (Sweden)

    A. Kolker

    2010-05-01

    Full Text Available Simultaneous real-time changes in mercury (Hg speciation- reactive gaseous Hg (RGM, elemental Hg (Hg°, and fine particulate Hg (Hg-PM2.5, were determined from June to November, 2007, in ambient air at three locations in rural Central Wisconsin. Known Hg emission sources within the airshed of the monitoring sites include: 1 a 1114 megawatt (MW coal-fired electric utility generating station; 2 a Hg-bed chlor-alkali plant; and 3 a smaller (465 MW coal-burning electric utility. Monitoring sites, showing sporadic elevation of Hg°, Hg-PM2.5, and RGM were positioned at distances of 25, 50 and 100 km northward of the larger electric utility. Median concentrations of Hg°, Hg-PM2.5, and RGM were 1.3–1.4 ng m−3, 2.6–5.0 pg m−3, and 0.6–0.8 pg m−3, respectively. A series of RGM events were recorded at each site. The largest, on 23 September, occurred under prevailing southerly winds, with a maximum RGM value (56.8 pg m-3 measured at the 100 km site, and corresponding elevated SO2 (10.4 ppbv; measured at 50 km site. The finding that RGM, Hg°, and Hg-PM2.5 are not always highest at the 25 km site, closest to the large generating station, contradicts the idea that RGM decreases with distance from a large point source. This may be explained if: 1 the 100 km site was influenced by emissions from the chlor-alkali facility or by RGM from regional urban sources; 2 the emission stack height of the larger power plant promoted plume transport at an elevation where the Hg is carried over the closest site; or 3 RGM was being generated in the plume through oxidation of Hg°. Operational changes at each emitter since 2007 should reduce their Hg output, potentially allowing quantification of the environmental benefit in future studies.

  10. Overhaul of the generator of the hydroelectric central station Ingeniero Carlos Ramirez Ulloa; Rehabilitacion del generador de la unidad 2 de la central hidroelectrica ingeniero Carlos Ramirez Ulloa

    Energy Technology Data Exchange (ETDEWEB)

    Robles Pimentel, Edgar [Instituto de Investigaciones Electricas, Cuernavaca (Mexico); Garcia Hernandez, Javier [Comision Federal de Electricidad, Mexico, D. F. (Mexico)

    1997-12-31

    In November 1995, the failure of the Unit 2 generator at the hydroelectric central station Ingeniero Carlos Ramirez Ulloa, El Caracol, occurred. The accident forced to carry out its overhaul. Here are presented the technical problems faced during the overhaul of the generator and analyzed the implemented solutions. [Espanol] En noviembre de 1995 ocurrio la falla del generador de la unidad 2 de la central hidroelectrica Ing. Carlos Ramirez Ulloa, El Caracol. El accidente obligo a llevar a cabo su rehabilitacion. Se presentan los problemas tecnicos enfrentados durante la rehabilitacion del generador y se discuten las soluciones implementadas.

  11. Infiltration Pattern of Blood Monocytes into the Central Nervous System during Experimental Herpes Simplex Virus Encephalitis.

    Directory of Open Access Journals (Sweden)

    Rafik Menasria

    Full Text Available The kinetics and distribution of infiltrating blood monocytes into the central nervous system and their involvement in the cerebral immune response together with resident macrophages, namely microglia, were evaluated in experimental herpes simplex virus 1 (HSV-1 encephalitis (HSE. To distinguish microglia from blood monocyte-derived macrophages, chimeras were generated by conditioning C57BL/6 recipient mice with chemotherapy regimen followed by transplantation of bone morrow-derived cells that expressed the green fluorescent protein. Mice were infected intranasally with a sub-lethal dose of HSV-1 (1.2 x 10(6 plaque forming units. Brains were harvested prior to and on days 4, 6, 8 and 10 post-infection for flow cytometry and immunohistochemistry analysis. The amounts of neutrophils (P < 0.05 and "Ly6C hi" inflammatory monocytes (P < 0.001 significantly increased in the CNS compared to non-infected controls on day 6 post-infection, which corresponded to more severe clinical signs of HSE. Levels decreased on day 8 for both leukocytes subpopulations (P < 0.05 for inflammatory monocytes compared to non-infected controls to reach baseline levels on day 10 following infection. The percentage of "Ly6C low" patrolling monocytes significantly increased (P < 0.01 at a later time point (day 8, which correlated with the resolution phase of HSE. Histological analysis demonstrated that blood leukocytes colonized mostly the olfactory bulb and the brainstem, which corresponded to regions where HSV-1 particles were detected. Furthermore, infiltrating cells from the monocytic lineage could differentiate into activated local tissue macrophages that express the microglia marker, ionized calcium-binding adaptor molecule 1. The lack of albumin detection in the brain parenchyma of infected mice showed that the infiltration of blood leukocytes was not necessarily related to a breakdown of the blood-brain barrier but could be the result of a functional recruitment. Thus

  12. Production patterns of packaging waste categories generated at typical Mediterranean residential building worksites.

    Science.gov (United States)

    González Pericot, N; Villoria Sáez, P; Del Río Merino, M; Liébana Carrasco, O

    2014-11-01

    The construction sector is responsible for around 28% of the total waste volume generated in Europe, which exceeds the amount of household waste. This has led to an increase of different research studies focusing on construction waste quantification. However, within the research studies made, packaging waste has been analyzed to a limited extent. This article focuses on the packaging waste stream generated in the construction sector. To this purpose current on-site waste packaging management has been assessed by monitoring ten Mediterranean residential building works. The findings of the experimental data collection revealed that the incentive measures implemented by the construction company to improve on-site waste sorting failed to achieve the intended purpose, showing low segregation ratios. Subsequently, through an analytical study the generation patterns for packaging waste are established, leading to the identification of the prevailing kinds of packaging and the products responsible for their generation. Results indicate that plastic waste generation maintains a constant trend throughout the whole construction process, while cardboard becomes predominant towards the end of the construction works with switches and sockets from the electricity stage. Understanding the production patterns of packaging waste will be beneficial for adapting waste management strategies to the identified patterns for the specific nature of packaging waste within the context of construction worksites. PMID:25081852

  13. Steep REE patterns and enriched Pb isotopes in southern Central American arc magmas: Evidence for forearc subduction erosion?

    Science.gov (United States)

    Goss, A. R.; Kay, S. M.

    2006-05-01

    The appearance of adakitic magmas with steep rare earth element (REE) patterns in southern Costa Rica and Panama at ˜4 Ma coincides with the collision of the Cocos Ridge and the inception of slab shallowing along the margin. Distinctly higher 206Pb/204Pb and 208Pb/204Pb ratios in these adakitic lavas than in older Miocene lavas suggest that components enriched in radiogenic Pb also entered the mantle magma source at ˜4 Ma. Published Pb-isotopic data for Central American arc lavas show that a similar radiogenic component is not present in lavas farther north and that maxima in post-Miocene 206Pb/204Pb and 208Pb/204Pb ratios occur in central Costa Rica and western Panama. Cretaceous and early Tertiary ophiolites in the forearc, whose origins have been linked to the Galápagos hot spot, show a similar spatial pattern in Pb isotopic ratios. The incorporation of ophiolitic forearc crust into the mantle wedge by forearc subduction erosion can explain the along-arc spatial and temporal pattern of Pb-isotopic ratios in southern Central American arc lavas. Partial melting of crust removed from the base of the forearc and subjected to high-pressure metamorphism in the subduction channel provides an explanation for the steep adakitic REE patterns in some Costa Rican and Panamanian arc lavas.

  14. Intake-to-delivered-energy ratios for central station and distributed electricity generation in California

    International Nuclear Information System (INIS)

    In previous work, we showed that the intake fraction (iF) for nonreactive primary air pollutants was 20 times higher in central tendency for small-scale, urban-sited distributed electricity generation (DG) sources than for large-scale, central station (CS) power plants in California [Heath, G.A., Granvold, P.W., Hoats, A.S., Nazaroff, W.W., 2006. Intake fraction assessment of the air pollutant exposure implications of a shift toward distributed electricity generation. Atmospheric Environment 40, 7164-7177]. The present paper builds on that study, exploring pollutant- and technology-specific aspects of population inhalation exposure from electricity generation. We compare California's existing CS-based system to one that is more reliant on DG units sited in urban areas. We use Gaussian plume modeling and a GIS-based exposure analysis to assess 25 existing CSs and 11 DG sources hypothetically located in the downtowns of California's most populous cities. We consider population intake of three pollutants - PM2.5, NOx and formaldehyde - directly emitted by five DG technologies - natural gas (NG)-fired turbines, NG internal combustion engines (ICE), NG microturbines, diesel ICEs, and fuel cells with on-site NG reformers. We also consider intake of these pollutants from existing CS facilities, most of which use large NG turbines, as well as from hypothetical facilities located at these same sites but meeting California's best-available control technology standards. After systematically exploring the sensitivity of iF to pollutant decay rate, the iFs for each of the three pollutants for all DG and CS cases are estimated. To efficiently compare the pollutant- and technology-specific exposure potential on an appropriate common basis, a new metric is introduced and evaluated: the intake-to-delivered-energy ratio (IDER). The IDER expresses the mass of pollutant inhaled by an exposed population owing to emissions from an electricity generation unit per quantity of electric

  15. Production patterns of packaging waste categories generated at typical Mediterranean residential building worksites

    Energy Technology Data Exchange (ETDEWEB)

    González Pericot, N., E-mail: natalia.gpericot@upm.es [Escuela Técnica Superior de Edificación, Universidad Politécnica de Madrid, Calle Juan de Herrera n°6, 28040 Madrid (Spain); Villoria Sáez, P., E-mail: paola.villoria@upm.es [Escuela Técnica Superior de Edificación, Universidad Politécnica de Madrid, Calle Juan de Herrera n°6, 28040 Madrid (Spain); Del Río Merino, M., E-mail: mercedes.delrio@upm.es [Escuela Técnica Superior de Edificación, Universidad Politécnica de Madrid, Calle Juan de Herrera n°6, 28040 Madrid (Spain); Liébana Carrasco, O., E-mail: oscar.liebana@uem.es [Escuela de Arquitectura, Universidad Europea de Madrid, Calle Tajo s/n, 28670 Villaviciosa de Odón (Spain)

    2014-11-15

    Highlights: • On-site segregation level: 1.80%; training and motivation strategies were not effective. • 70% Cardboard waste: from switches and sockets during the building services stage. • 40% Plastic waste: generated during structures and partition works due to palletizing. • >50% Wood packaging waste, basically pallets, generated during the envelope works. - Abstract: The construction sector is responsible for around 28% of the total waste volume generated in Europe, which exceeds the amount of household waste. This has led to an increase of different research studies focusing on construction waste quantification. However, within the research studies made, packaging waste has been analyzed to a limited extent. This article focuses on the packaging waste stream generated in the construction sector. To this purpose current on-site waste packaging management has been assessed by monitoring ten Mediterranean residential building works. The findings of the experimental data collection revealed that the incentive measures implemented by the construction company to improve on-site waste sorting failed to achieve the intended purpose, showing low segregation ratios. Subsequently, through an analytical study the generation patterns for packaging waste are established, leading to the identification of the prevailing kinds of packaging and the products responsible for their generation. Results indicate that plastic waste generation maintains a constant trend throughout the whole construction process, while cardboard becomes predominant towards the end of the construction works with switches and sockets from the electricity stage. Understanding the production patterns of packaging waste will be beneficial for adapting waste management strategies to the identified patterns for the specific nature of packaging waste within the context of construction worksites.

  16. Production patterns of packaging waste categories generated at typical Mediterranean residential building worksites

    International Nuclear Information System (INIS)

    Highlights: • On-site segregation level: 1.80%; training and motivation strategies were not effective. • 70% Cardboard waste: from switches and sockets during the building services stage. • 40% Plastic waste: generated during structures and partition works due to palletizing. • >50% Wood packaging waste, basically pallets, generated during the envelope works. - Abstract: The construction sector is responsible for around 28% of the total waste volume generated in Europe, which exceeds the amount of household waste. This has led to an increase of different research studies focusing on construction waste quantification. However, within the research studies made, packaging waste has been analyzed to a limited extent. This article focuses on the packaging waste stream generated in the construction sector. To this purpose current on-site waste packaging management has been assessed by monitoring ten Mediterranean residential building works. The findings of the experimental data collection revealed that the incentive measures implemented by the construction company to improve on-site waste sorting failed to achieve the intended purpose, showing low segregation ratios. Subsequently, through an analytical study the generation patterns for packaging waste are established, leading to the identification of the prevailing kinds of packaging and the products responsible for their generation. Results indicate that plastic waste generation maintains a constant trend throughout the whole construction process, while cardboard becomes predominant towards the end of the construction works with switches and sockets from the electricity stage. Understanding the production patterns of packaging waste will be beneficial for adapting waste management strategies to the identified patterns for the specific nature of packaging waste within the context of construction worksites

  17. Water supply patterns in two agricultural areas of Central Germany under climate change conditions

    Directory of Open Access Journals (Sweden)

    M. H. Tölle

    2012-04-01

    Full Text Available Increasing emissions of greenhouse gases and increasing prices for fossil fuels have highlighted the demand for CO2 "neutral" renewable energy sources, e.g. short rotation forestry systems used for bioenergy. These systems might be vulnerable to changes in temperature, precipitation and occurrence of extreme weather events. To estimate success or failure of such short rotation coppices in a certain area we need regional climate projections and risk assessment. Changes of water supply patterns in two agriculturally extensively used regions in Central Germany (around Göttingen and Großfahner with different climate conditions but both in the temperate climate zone are explored. The study is carried out under present conditions as well as under projected climate change conditions (1971–2100 using A1B and B1 climate scenarios downscaled for Europe. Analysis of precipitation bias shows regional differences: a strong bias in Göttingen area and a weaker bias in the Großfahner area. A bias correction approach, Quantile mapping, is applied to the ensemble results for both areas for winter and summer seasons. By using quantile regression on the seasonal Standardized Precipitation Indices (SPIs as indicator for water supply conditions we found that precipitation is expected to increase in winter in all quantiles of the distribution for Göttingen area during the 21th century. Heavy precipitation is also expected to increase for Großfahner area suggesting a trend to wetter extremes in winter for the future. This winter precipitation increase could trigger runoff and soil erosion risk enhancing the severity of floods. Increasing winter availability of water could enhance local water supply in spring. For both areas no significant change in summer was found over the whole time period. Although the climate change signal of the SPI indicate mild dryer conditions in summer at the end of the 21st century which may trigger water shortage and

  18. Composite axilens-axicon diffractive optical elements for generation of ring patterns with high focal depth

    Science.gov (United States)

    Dharmavarapu, Raghu; Vijayakumar, A.; Brunner, R.; Bhattacharya, Shanti

    2016-03-01

    A binary Fresnel Zone Axilens (FZA) is designed for the infinite conjugate mode and the phase profile of a refractive axicon is combined with it to generate a composite Diffractive Optical Element (DOE). The FZA designed for two focal lengths generates a line focus along the propagation direction extending between the two focal planes. The ring pattern generated by the axicon is focused through this distance and the radius of the ring depends on the propagation distance. Hence, the radius of the focused ring pattern can be tuned, during the design process, within the two focal planes. The integration of the two functions was carried out by shifting the location of zones of FZA with respect to the phase profile of the refractive axicon resulting in a binary composite DOE. The FZAs and axicons were designed for different focal depth values and base angles respectively, in order to achieve different ring radii within the focal depth of each element. The elements were simulated using scalar diffraction formula and their focusing characteristics were analyzed. The DOEs were fabricated using electron beam direct writing and evaluated using a fiber coupled diode laser. The tunable ring patterns generated by the DOEs have prospective applications in microdrilling as well as microfabrication of circular diffractive and refractive optical elements.

  19. The Camera Itself as a Calibration Pattern: A Novel Self-Calibration Method for Non-Central Catadioptric Cameras

    OpenAIRE

    Xing Dai; Zhiyu Xiang; Bo Sun

    2012-01-01

    A novel and practical self-calibration method for misaligned non-central catadioptric cameras is proposed in this paper. Without the aid of any special calibration patterns in the scene, the developed method is able to automatically estimate the pose parameters of the mirror with respect to the perspective camera. First it uses the ellipse corresponding to the mirror boundary in the image to compute the possible solutions for mirror postures. With two pose candidates, thereafter we propose a ...

  20. Biogeographic patterns in below-ground diversity in New York City's Central Park are similar to those observed globally

    OpenAIRE

    Ramirez, Kelly S.; Leff, Jonathan W.; Barberán, Albert; Bates, Scott Thomas; Betley, Jason; Crowther, Thomas W.; Kelly, Eugene F.; Oldfield, Emily E.; Shaw, E. Ashley; Steenbock, Christopher; Bradford, Mark A.; Wall, Diana H.; Fierer, Noah

    2014-01-01

    Soil biota play key roles in the functioning of terrestrial ecosystems, however, compared to our knowledge of above-ground plant and animal diversity, the biodiversity found in soils remains largely uncharacterized. Here, we present an assessment of soil biodiversity and biogeographic patterns across Central Park in New York City that spanned all three domains of life, demonstrating that even an urban, managed system harbours large amounts of undescribed soil biodiversity. Despite high variab...

  1. Spatial pattern analysis of landslide using landscape metrics and logistic regression: a case study in Central Taiwan

    OpenAIRE

    Lin, Y.-P.; Chu, H.-J.; WU, C.-F.

    2010-01-01

    The Chi-Chi Earthquake of September 1999 in Central Taiwan registered a moment magnitude MW of 7.6 on the Richter scale, causing widespread landslides. Subsequent typhoons associated with heavy rainfalls triggered the landslides. The study investigates multi-temporal landslide images from spatial analysis between 1996 and 2005 in the Chenyulan Watershed, Taiwan. Spatial patterns in various landslide frequencies were detected using...

  2. Pattern of non-obstetric infectious recto-vaginal fistula: a case series and literature review in Cameroon, Central Africa

    OpenAIRE

    Pierre Marie Tebeu; Roger Guy Michel Ekono; Jovanny Tsuala Fouogue; Gregory Ekane Halle; Joel Domgue Fokom; Charles Henry Rochat

    2016-01-01

    Background: Perineal infection is an uncommon cause of non-obstetrical recto-vaginal fistula (RVF) which is associated with HIV infection. Cameroon (Central Africa) is in the fistula belt but infectious RVFs have not yet been deeply studied in the country. We therefore sought to determine the pattern of non-obstetric infectious RVF in Cameroon. Methods: We carried out a cross-sectional and descriptive review of non-obstetric infectious RVFs managed at the Yaound and eacute; University Teac...

  3. Determination of activity by gamma spectrometry of radionuclides present in drums of residues generated in nuclear centrals

    International Nuclear Information System (INIS)

    The generation of radioactive residuals in nuclear centrals as CNA I (Atucha I Nuclear Central) and CNE (Embalse Nuclear Central) makes that the measurement of those radionuclides has been a previous stage to the waste management. A method used in those nuclear centrals it is the gamma spectrometry with HPGe detectors, previous to the immobilization of the residual in a cemented matrix, with this the contact with the external agents and its possible dispersion to the atmosphere in the short term is avoided. The ARN (Nuclear Regulatory Authority) of Argentina it carries out periodically intercomparisons and evaluations of the measurement and procedures systems used in the nuclear power stations for the correct measurement and determination of activity of radioactive residuals by gamma spectrometry. In this work an independent method of measurement is exposed to the nuclear power stations. To determine the activity of the residuals by gamma spectrometry deposited in drums, it is required of the precise knowledge of the efficiency curve for such geometry and matrix. Due to the RNA doesn't have a pattern of these characteristics, a mathematical model has been used to obtain this efficiency curve. For it, it is necessary to determine previously: 1) the geometric efficiency or solid angle sustained by the source-detector system (drum-detector) applying a mathematical model described in this work. 2) To estimate the auto-attenuation factor that present the photons in the cemented matrix, these calculations are carried out with a simple equation and its are verified with the Micro Shield 6.10 program. The container commonly used by these nuclear power stations its are drums for 220 liters constructed with SAE 1010 steel and with a thickness of 0.127 cm, with an approximate weight 7.73 Kg., internal diameter of 57.1 cm, and height: 87 cm. The results obtained until the moment register a discrepancy from 5 to 10% with relationship to the measurements carried out by the

  4. Walking Pattern Generation of Dual-Arm Mobile Robot Using Preview Controller

    Directory of Open Access Journals (Sweden)

    P. Wu

    2012-09-01

    Full Text Available Based on the stability request of robot’s moving on the ground, the motion planning of dual-arm mobile robot when moving on the ground is studied and the preview control system is applied in the robot walking pattern generation. Direct question of robot kinematics in the extended task space is analyzed according to Degrees of Freedom configuration of the dual-arm mobile robot. It is proved that the preview control system could be used in the generation of robot Center of Mass forward trajectory through the building of double linear inverted pendulum model of dual-arm mobile robot. The sector gridding search algorithm is proposed and the reachable workspace which meets the Zero Moment Point stability principle when the robot moving on the ground is obtained. Tip Trajectory is generated through polynomial interpolation. Each joint curve is calculated using MATLAB which is imported to virtual physical model. The feasibility of gait generation is verified.

  5. SOM-based Pattern Generator: Pattern Generation Based on the Backward Projection in a Self-Organizing Map and Its Applications

    Science.gov (United States)

    Wakuya, Hiroshi; Ishiguma, Takahiro

    A major feature of the self-organizing map (SOM) is a topology-preserving projection from the input layer to the competitive layer, and it has been used mainly as an analytical tool for discovering underlying rules in the given data set. Even though recent splendid progress in this area, there are few novel ideas to break such a conventional style. On the contrary, based on its distinctive nature, a new method for generating patterns through backward projection from the competitive layer to the input layer is proposed recently. Moreover, a promising technology for producing animation as a series of backward-projected patterns along with any pathways on the competitive layer is presented. Then, in order to carry out further considerations, some computer simulations with a variety of posed stick figures are tried in this paper. After training, four kinds of pathways, which correspond to different movements such as dancing, exercising and walking, are prepared. Though some of them does not contain any training samples, all of them worked well as we have intended in advance. As a result, it is found that the proposed method shows good performance and it is also confirmed its effectiveness.

  6. A rule-based expert system for automatic control rod pattern generation for boiling water reactors

    International Nuclear Information System (INIS)

    This paper reports on an expert system for generating control rod patterns that has been developed. The knowledge is transformed into IF-THEN rules. The inference engine uses the Rete pattern matching algorithm to match facts, and rule premises and conflict resolution strategies to make the system function intelligently. A forward-chaining mechanism is adopted in the inference engine. The system is implemented in the Common Lisp programming language. The three-dimensional core simulation model performs the core status and burnup calculations. The system is successfully demonstrated by generating control rod programming for the 2894-MW (thermal) Kuosheng nuclear power plant in Taiwan. The computing time is tremendously reduced compared to programs using mathematical methods

  7. Photorefractive holographic moiré-like patterns for secure numerical code generation.

    Science.gov (United States)

    de Oliveira, G N; Oliveira, M E; dos Santos, P A M

    2013-03-15

    In this Letter, low-frequency photorefractive holographic moiré fringe patterns are proposed as secure numerical code generators that could be useful for storage or data transmission. These dynamic moiré patterns are holographically obtained by the superposition of two or more sinusoidal gratings with slightly different pitches. The Bi(12)TiO(20) photorefractive crystal sample is used as holographic medium. An optical numerical base was defined with patterns representing the 0, 1 and -1 digits as bits. Then, the complete set of these optical bits is combined to form bytes, where a numerical sequence is represented. The results show that the proposed numerical code is simple, robust and extremely secure, then could be used efficiently as standard numerical identification in robotic vision or eventually in storage or transmission of secure numerical data. PMID:23503288

  8. Australasian microtektites from the Central Indian Basin: Implications for ejecta distribution patterns

    Digital Repository Service at National Institute of Oceanography (India)

    ShyamPrasad, M.; Sudhakar, M.

    Microtektites belonging to the Australasian tektite strewn field have been recovered in one (SK-16/176) out of three cores examined from the Central Indian Basin. The microtektites have been identified based on their physical appearance...

  9. Pattern and predictors of neurological morbidities among childhood cerebral malaria survivors in central Sudan

    Directory of Open Access Journals (Sweden)

    Adil Mergani

    2015-01-01

    Interpretation & conclusion: Neurological sequelae are common due to childhood cerebral malaria in central Sudan. Their prediction at admission, clinical presentation and laboratory findings may guide clinical intervention and proper management that may decrease morbidity and improve CM consequences.

  10. Optimization of Active Vibration Control of a Laser Pattern Generator in Micro Lithography

    OpenAIRE

    Carlqvist, Per; Brattström, Patrik; During, Carl

    2010-01-01

    The extreme precision requirements in semiconductor manufacturing drive the need for an active vibration isolation system in a laser pattern generator. Optimization has been performed and evaluated in a model using a high level programming tool [1]. The areas of optimization were 1) Decoupling strategies for decentralized control and 2) Improved feed forward control. Only a limited description of the model itself is given here. More about the model is presented in [2] and [3].

  11. Fault simulation and test pattern generation for synchronous and asynchronous sequential circuits

    OpenAIRE

    Lee, Hyung Ki

    1993-01-01

    In this dissertation, we propose two fault simulators, called HOPE and HOPE2, and an autolllatic test pattern generator (ATPG), called ATHENA, for synchronous and asynchronous sequential circuits. HOPE is a parallel fault simulator for synchronous sequential circuits. In HOPE, a packet of 32 faults is simulated in parallel. Several new heuristics are employed in HOPE to accelerate the parallel fault simulation. The heuristics are 1) a reduction of faults to be simulated ...

  12. Patterns of illness in travelers visiting Mexico and Central America: the GeoSentinel experience

    OpenAIRE

    Flores-Figueroa, J; Okhuysen, P C; von Sonnenburg, F.; DuPont, H L; Libman, M D; Keystone, J S; Hale, D C; Burchard, G; Han, P V; Wilder-Smith, A.; Freedman, D O

    2011-01-01

    BACKGROUND: Mexico and Central America are important travel destinations for North American and European travelers. There is limited information on regional differences in travel related morbidity. METHODS: We describe the morbidity among 4779 ill travelers returned from Mexico and Central America who were evaluated at GeoSentinel network clinics during December 1996 to February 2010. RESULTS: The most frequent presenting syndromes included acute and chronic diarrhea, dermat...

  13. Towards pattern generation and chaotic series prediction with photonic reservoir computers

    Science.gov (United States)

    Antonik, Piotr; Hermans, Michiel; Duport, François; Haelterman, Marc; Massar, Serge

    2016-03-01

    Reservoir Computing is a bio-inspired computing paradigm for processing time dependent signals that is particularly well suited for analog implementations. Our team has demonstrated several photonic reservoir computers with performance comparable to digital algorithms on a series of benchmark tasks such as channel equalisation and speech recognition. Recently, we showed that our opto-electronic reservoir computer could be trained online with a simple gradient descent algorithm programmed on an FPGA chip. This setup makes it in principle possible to feed the output signal back into the reservoir, and thus highly enrich the dynamics of the system. This will allow to tackle complex prediction tasks in hardware, such as pattern generation and chaotic and financial series prediction, which have so far only been studied in digital implementations. Here we report simulation results of our opto-electronic setup with an FPGA chip and output feedback applied to pattern generation and Mackey-Glass chaotic series prediction. The simulations take into account the major aspects of our experimental setup. We find that pattern generation can be easily implemented on the current setup with very good results. The Mackey-Glass series prediction task is more complex and requires a large reservoir and more elaborate training algorithm. With these adjustments promising result are obtained, and we now know what improvements are needed to match previously reported numerical results. These simulation results will serve as basis of comparison for experiments we will carry out in the coming months.

  14. Variable resolution pattern generation for the Associative Memory of the ATLAS FTK project

    CERN Document Server

    Annovi, A; The ATLAS collaboration; Faulkner, G; Giannetti, P; Jiang, Z; Luongo, C; Pandini, C; Shochet, M; Tompkins, L; Volpi, G

    2013-01-01

    The Associative Memory (AM) chip is special device that allows to find coincidence patterns, or just patterns, between the incoming data in up to 8 parallel streams. The latest AM chip has been designed to receive silicon clusters generated in 8 layers of the ATLAS silicon detector sensor, to perform parallel track pattern matching at high rate and it will be the core of the FTK project. Data going through each of the busses are compared with a bank of patterns and AM chip looks for matches in each line, like commercial content addressable memory (CAM). The high density of hits expected in the ATLAS inner detector from 2015 put a challenge in the capability of the AM chip in rejecting random coincidences, requiring either an extremely high number of high precision patterns, with increasing costs and complexity of the system, or more flexible solutions. For this reason in the most recent prototype of the AM chip ternary cells have been added in the logic, allowing “don’t care” (DC) bits in the match. Hav...

  15. Fast Lagrangian relaxation for constrained generation scheduling in a centralized electricity market

    International Nuclear Information System (INIS)

    This paper proposes a fast Lagrangian relaxation (FLR) for constrained generation scheduling (CGS) problem in a centralized electricity market. FLR minimizes the consumer payment rather than the total supply cost subject to the power balance, spinning reserve, transmission line, and generator operating constraints. FLR algorithm is improved by new initialization of Lagrangian multipliers and adaptive adjustment of Lagrangian multipliers. The adaptive subgradient method using high quality initial feasible multipliers requires much less number of iterations to converge, leading to a faster computational time. If congestion exists, the alleviating congestion index is proposed for congestion management. Finally, the unit decommitment is performed to prevent excessive spinning reserve. The FLR for CGS is tested on the 4 unit and the IEEE 24 bus reliability test systems. The proposed uniform electricity price results in a lower consumer payment than system marginal price based on uniformly fixed cost amortized allocation, non-uniform price, and electricity price incorporating side payment, leading to a lower electricity price. In addition, observations on objective functions, pricing scheme comparison and interpretation of Lagrangian multipliers are provided. (author)

  16. Rare earth element patterns of the Central Indian Basin sediments related to their lithology

    Digital Repository Service at National Institute of Oceanography (India)

    Nath, B.N.; Roelandts, I.; Sudhakar, M.; Pluger, W.L.

    with terrigenous sediments, positive Ce anomalies with siliceous sediments, negative Ce and positive Eu anomalies with calcareous sediments, and LREE-depleted patterns with pelagic red clays. There is no relation of any REE fractionation to bottom water redox...

  17. Spatial organization and state-dependent mechanisms for respiratory rhythm and pattern generation.

    Science.gov (United States)

    Rybak, Ilya A; Abdala, Ana P L; Markin, Sergey N; Paton, Julian F R; Smith, Jeffrey C

    2007-01-01

    The brainstem respiratory network can operate in multiple functional states engaging different state-dependent neural mechanisms. These mechanisms were studied in the in situ perfused rat brainstem-spinal cord preparation using sequential brainstem transections and administration of riluzole, a pharmacological blocker of persistent sodium current (INaP). Dramatic transformations in the rhythmogenic mechanisms and respiratory motor pattern were observed after removal of the pons and subsequent medullary transactions down to the rostral end of pre-Bötzinger complex (pre-BötC). A computational model of the brainstem respiratory network was developed to reproduce and explain these experimental findings. The model incorporates several interacting neuronal compartments, including the ventral respiratory group (VRG), pre-BötC, Bötzinger complex (BötC), and pons. Simulations mimicking the removal of circuit components following transections closely reproduce the respiratory motor output patterns recorded from the intact and sequentially reduced brainstem preparations. The model suggests that both the operating rhythmogenic mechanism (i.e., network-based or pacemaker-driven) and the respiratory pattern generated (e.g., three-phase, two-phase, or one-phase) depend on the state of the pre-BötC (expression of INaP-dependent intrinsic rhythmogenic mechanisms) and the BötC (providing expiratory inhibition in the network). At the same time, tonic drives from pons and multiple medullary chemoreceptive sites appear to control the state of these compartments and hence the operating rhythmogenic mechanism and motor pattern. Our results suggest that the brainstem respiratory network has a spatial (rostral-to-caudal) organization extending from the rostral pons to the VRG, in which each functional compartment is controlled by more rostral compartments. The model predicts a continuum of respiratory network states relying on different contributions of intrinsic cellular properties

  18. Fast oscillations during gasping and other non-eupneic respiratory behaviors: Clues to central pattern generation

    OpenAIRE

    Ghali, Michael George Zaki; Marchenko, Vitaliy

    2013-01-01

    The mammalian nervous system exhibits fast synchronous oscillations, which are especially prominent in respiratory-related nerve discharges. In the phrenic nerve, they include high- (HFO), medium- (MFO), and low-frequency (LFO) oscillations. Because motoneurons firing at HFO-related frequencies had never been recorded, an epiphenomenological mechanism for their existence had been posited. We have recently recorded phrenic motoneurons firing at HFO-related frequencies in unanesthetized decereb...

  19. Reticular activating system of a central pattern generator: premovement electrical potentials

    OpenAIRE

    Tapia, Jesus A; Trejo, Argelia; Linares, Pablo; Alva, J Manuel; Kristeva, Rumyana; Manjarrez, Elias

    2013-01-01

    For the first time, here we characterize a bulbar reticular activating system (RAS) of neurons in decerebrate, deafferented and decerebellated cats producing a premovement electrical potential that we named obex slow potential (OSP). The OSP occurs about 0.8 ± 0.4 sec prior to the onset of a fictive-scratching-episode. Here, we describe two classes of bulbar neurons, off-on, which are silent but exhibit a 80 ± 56 Hz firing discharge at the beginning of (and during) the OSP, and on-off interne...

  20. An optogenetic investigation of the control and development of the spinal central pattern generator in zebrafish

    OpenAIRE

    Warp, Erica Kirsten

    2012-01-01

    The nervous system directly controls the muscles of the body, and thus, the behavior of the animal. An understanding of the neural circuits and cell types that mediate and control behavior would give us insight into the mechanisms by which the nervous system operates and would also contribute to the development of therapies and treatments for neurological disorders and diseases that result in locomotor deficits. Some behaviors are organized by constant voluntary drive, while others, which req...

  1. Hierarchical reinforcement learning and central pattern generators for modeling the development of rhythmic manipulation skills

    OpenAIRE

    Ciancio A.L.; Zollo L.; Guglielmelli E.; Caligiore D.; Baldassarre G.

    2011-01-01

    The development of manipulation skills is a fundamental process for young primates as it leads them to acquire the capacity to modify the world to their advantage. As other motor skills, manipulation develops on the basis of motor babbling processes which are initially heavily based on the production of rhythmic movements. We propose a computational bio-inspired model to investigate the development of functional rhythmic hand skills from initially unstructured movements. The model is based on...

  2. An Analog VLSI Model of Central Pattern Generation in the Leech

    OpenAIRE

    Siegel, Micah S

    1994-01-01

    I detail the design and construction of an analog VLSI model of the neural system responsible for swimming behaviors of the leech. Why the leech? The biological network is small and relatively well understood, and the silicon model can therefore span three levels of organization in the leech nervous system (neuron, ganglion, system); it represents one of the first comprehensive models of leech swimming operating in real-time. The circuit employs biophysically motivated analog neurons netwo...

  3. Diversity of Sonneratia alba in coastal area of Central Java based on isozymic patterns of esterase and peroxidase

    Directory of Open Access Journals (Sweden)

    AHMAD DWI SETYAWAN

    2009-07-01

    Full Text Available Setyawan AD. 2009. Diversity of Sonneratia alba in coastal area of Central Java based on isozymic patterns of esterase and peroxidase. Nusantara Bioscience 1: 92-103. The study was intended to observe the diversity and the relationship of Sonneratia alba in southern and northern coast of Central Java Province based on isozymic patterns of esterase and peroxidase. This research was conducted in July until December 2003, at six sites, i.e. Wulan (WUL, Juwana (JUW, Pasar Bangi (PAS, in the northern coast, and Bogowonto (BOG, Motean (MOT, and Muara Dua (MUA in the southern coast. The laboratory assay was conducted in Central Laboratory of Mathematics and Natural Sciences, Sebelas Maret University (UNS Surakarta. The seedling plant samples that were collected from enam mangrove habitats transplanted in green house in the laboratory. There were 20 individual samples each sites. The result indicated that the individual of S. alba of the same or near location has the same genetic diversity in common, because the genetic exchange on a same population was higher than on a different population. Therefore, the populations of S. alba from northern coast had higher similarity each others than southern coast one, on the other way the populations from southern coast had higher similarity each others than northern coast one.

  4. Generation of spatially periodic patterns by a mechanical instability: a mechanical alternative to the Turing model.

    Science.gov (United States)

    Harris, A K; Stopak, D; Warner, P

    1984-04-01

    We have studied the generation of spatial patterns created by mechanical (rather than chemical) instabilities. When dissociated fibroblasts are suspended in a gel of reprecipitated collagen, and the contraction of the gel as a whole is physically restrained by attachment of its margin to a glass fibre meshwork, then the effect of the fibroblasts' traction is to break up the cell-matrix mixture into a series of clumps or aggregations of cells and compressed matrix. These aggregations are interconnected by linear tracts of collagen fibres aligned under the tensile stress exerted by fibroblast traction. The patterns generated by this mechanical instability vary depending upon cell population density and other factors. Over a certain range of cell concentrations, this mechanical instability yields geometric patterns which resemble but are usually much less regular than the patterns which develop normally in the dermis of developing bird skin. We propose that an equivalent mechanical instability, occurring during the embryonic development of this skin, could be the cause not only of the clumping of dermal fibroblasts to form the feather papillae, but also of the alignment of collagen fibres into the characteristic polygonal network of fibre bundles - which interconnect these papillae and which presage the subsequent pattern of the dermal muscles serving to control feather movements. More generally, we suggest that this type of mechanical instability can serve the morphogenetic functions for which Turing's chemical instability and other reaction-diffusion systems have been proposed. Mechanical instabilities can create physical structures directly, in one step, in contrast to the two or more steps which would be required if positional information first had to be specified by chemical gradients and then only secondarily implemented in physical form. In addition, physical forces can act more quickly and at much longer range than can diffusing chemicals and can generate a

  5. A Novel Biped Pattern Generator Based on Extended ZMP and Extended Cart-table Model

    Directory of Open Access Journals (Sweden)

    Guangbin Sun

    2015-07-01

    Full Text Available This paper focuses on planning patterns for biped walking on complex terrains. Two problems are solved: ZMP (zero moment point cannot be used on uneven terrain, and the conventional cart-table model does not allow vertical CM (centre of mass motion. For the ZMP definition problem, we propose the extended ZMP (EZMP concept as an extension of ZMP to uneven terrains. It can be used to judge dynamic balance on universal terrains. We achieve a deeper insight into the connection and difference between ZMP and EZMP by adding different constraints. For the model problem, we extend the cart-table model by using a dynamic constraint instead of constant height constraint, which results in a mathematically symmetric set of three equations. In this way, the vertical motion is enabled and the resultant equations are still linear. Based on the extended ZMP concept and extended cart-table model, a biped pattern generator using triple preview controllers is constructed and implemented simultaneously to three dimensions. Using the proposed pattern generator, the Atlas robot is simulated. The simulation results show the robot can walk stably on rather complex terrains by accurately tracking extended ZMP.

  6. 3D Quaternary deformation pattern in the central Po Plain (Northern Italy)

    Science.gov (United States)

    Sileo, G.; Mueller, K.; Michetti, A. M.; Livio, F.; Berlusconi, A.; Carcano, C.; Rogledi, S.; Vittori, E.

    2009-04-01

    The Po Plain is a foredeep basin flanked by the two major and active orogens of the Italian Peninsula, the Alps to the North and the Apennines to the South. The basin has a quasi - triangular shape and grades longitudinally to the East in the Adriatic Sea. We used petroleum industry seismic reflection data acquired by ENI E&P in the Central Po Plain, over an area spanning about 6800 km2 from Lake Como to the W to Lake Garda to the E, and from the Lombardian Southern Alps to the N and the Emilia Apennines to the S, in order to analyze and interpret selected seismic reflectors and to define the evolution in space and time of the local active tectonic structures. Folds associated with underlying thrusts were recognized based on deformation recorded by two regional sequence boundary horizons, i.e. the ‘A' Surface (1.6 Myr) and the ‘R' Surface (0. 9 Myr; e.g., Carcano & Piccin, 2002; Muttoni et al., 2003), characterized by good stratigraphic and age bracketing, and marking significant changes in the sedimentary architecture of the Po Basin. Age controls are based on stratigraphic, paleontological and magnetostratigraphic analysis by ENI E&P and Regione Lombardia (Carcano & Piccin, 2002; Scardia et al., 2006). The analysis of strain recorded by these horizons allowed us to: A) recognize a belt of active fold and thrust structures, each 10 to 20 km long, arranged with an en-echelon pattern across the whole Po Basin, and B) analyze their evolution over the Quaternary. 'A' surface (1.6 Myr) The ‘A' surface has been mapped over about 7800 Km2. From North to South four major morphobathymetric domains can be defined in the Pleistocene marine Po Basin: an Alpine platform domain, a slope that links it with the wider central basin domain, a smaller and steeper slope and an Apennine platform domain. The basin shape has an asymmetric transversal profile and is ca. 40 km wide. Several tectonic structures affect this surface. On the Alpine platform domain two small structures

  7. Quantum properties of transverse pattern formation in second-harmonic generation

    DEFF Research Database (Denmark)

    Bache, Morten; Scotto, P.; Zambrini, R.;

    2002-01-01

    transverse wave number, which are not identified in a linearized analysis, are also described. The intensity differences between opposite points of the far fields are shown to exhibit sub-Poissonian statistics, revealing the quantum nature of the correlations. We observe twin beam correlations in both the......We investigate the spatial quantum noise properties of the one-dimensional transverse pattern formation instability in intracavity second-harmonic generation. The Q representation of a quasi-probability distribution is implemented in terms of nonlinear stochastic Langevin equations. We study these...... pattern formation, beams with opposite direction of the off-axis critical wave numbers are shown to be highly correlated. This is observed for the fundamental field, for the second-harmonic field, and also for the cross-correlation between the two fields. Nonlinear correlations involving the homogeneous...

  8. Reduced Test Pattern Generation of Multiple SIC Vectors with Input and Output Delay Faults

    Directory of Open Access Journals (Sweden)

    P.T.Sairam

    2014-11-01

    Full Text Available In recent years, the design for low power has become one of the greatest challenges in high-performance very large scale integration (VLSI design. Most of the methods focus on the power consumption during normal mode operation, while test mode operation has not normally been a predominant concern. However, it has been found that the power consumed during test mode operation is often much higher than during normal mode operation [1]. This is because most of the consumed power results from the switching activity in the nodes of the circuit under test (CUT, which is much higher during test mode than during normal mode operation [1]–[3]. In the proposed pattern, each generated vector applied to each scan chain is an SIC vector, which can minimize the input transition and reduce test power. In VLSI testing, power reduction is achieved by increasing the correlation between consecutive test patterns.

  9. Distribution patterns of medicinal plants along an elevational gradient in central Himalaya, Nepal

    Czech Academy of Sciences Publication Activity Database

    Rokaya, Maan Bahadur; Münzbergová, Zuzana; Shrestha, M.R.; Timsina, B.

    2012-01-01

    Roč. 9, č. 2 (2012), s. 201-213. ISSN 1672-6316 R&D Projects: GA ČR GA526/09/0549 Institutional research plan: CEZ:AV0Z60050516 Keywords : distribution patterns * medicinal plants * unimodal relationships Subject RIV: EF - Botanics Impact factor: 0.664, year: 2012

  10. Distribution pattern and morphochemical relationships of manganese nodules from the Central Indian Basin

    Digital Repository Service at National Institute of Oceanography (India)

    Banerjee, R.; Miura, H.

    smooth and rough surfaces respectively) occur on almost all sediments, but in variable proportions. Thus, the overall distribution pattern shows that small nodules (less than 4-cm diameters) of lower grade (average value Ni + Cu + Co = 1.21%) with smooth...

  11. Czech alien flora and the historical pattern of its formation: what came first to Central Europe?

    Czech Academy of Sciences Publication Activity Database

    Pyšek, Petr; Sádlo, Jiří; Mandák, Bohumil; Jarošík, V.

    2003-01-01

    Roč. 135, - (2003), s. 122-130. ISSN 0029-8549 R&D Projects: GA AV ČR KSK6005114; GA ČR GA206/99/1239 Institutional research plan: CEZ:AV0Z6005908 Keywords : alien flora * immigration pattern * invasion history Subject RIV: EF - Botanics Impact factor: 3.128, year: 2003

  12. Source region of volcanism and seismicity pattern beneath Central American volcanoes

    Czech Academy of Sciences Publication Activity Database

    Špičák, Aleš; Hanuš, Václav; Vaněk, Jiří

    2005-01-01

    Roč. 236, 1/2 (2005), s. 149-172. ISSN 0077-7749 R&D Projects: GA ČR GA205/03/1203; GA AV ČR IAA3012303 Institutional research plan: CEZ:AV0Z30120515 Keywords : Central America * subduction * convergent plate margins Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 0.721, year: 2005

  13. Legume Diversity Patterns in West Central Africa: Influence of Species Biology on Distribution Models

    OpenAIRE

    Manuel de la Estrella; Mateo, Rubén G.; Wieringa, Jan J.; Barbara Mackinder; Jesús Muñoz

    2012-01-01

    OBJECTIVES: Species Distribution Models (SDMs) are used to produce predictions of potential Leguminosae diversity in West Central Africa. Those predictions are evaluated subsequently using expert opinion. The established methodology of combining all SDMs is refined to assess species diversity within five defined vegetation types. Potential species diversity is thus predicted for each vegetation type respectively. The primary aim of the new methodology is to define, in more detail, areas of sp...

  14. Analysis of Soil Heavy Metal Pollution and Pattern in Central Transylvania

    OpenAIRE

    Lorentz Jäntschi; Sorana D. Bolboacă; Mihai Todică; Constantin Cosma; Ioan Suciu

    2008-01-01

    The concentration of five soil heavy metals (Pb, Co, Cr, Cu, Hg) was measured in forty sampling sites in central Transylvania, Romania, regions known as centres of pollution due to the chemical and metallurgical activities. The soil samples were collected from locations where the ground is not sliding and the probability of alluvial deposits is small. The concentration of heavy metals was measured by using the Inductively Coupled Plasma Spectrometry method. Data were verified by using the Neu...

  15. Detecting Events and Patterns in Large-Scale User Generated Textual Streams with Statistical Learning Methods

    OpenAIRE

    Lampos, Vasileios

    2012-01-01

    A vast amount of textual web streams is influenced by events or phenomena emerging in the real world. The social web forms an excellent modern paradigm, where unstructured user generated content is published on a regular basis and in most occasions is freely distributed. The present Ph.D. Thesis deals with the problem of inferring information - or patterns in general - about events emerging in real life based on the contents of this textual stream. We show that it is possible to extract valua...

  16. DNA Image Pro -- A Tool for Generating Pixel Patterns using DNA Tile Assembly

    OpenAIRE

    Limbachiya, Dixita; Trivedi, Dhaval; Gupta, Manish K.

    2016-01-01

    Self-assembly is a process found everywhere in the Nature. In particular, it is known that DNA self-assembly is Turing universal. Thus one can do arbitrary computations or build nano-structures using DNA self-assembly. In order to understand the DNA self-assembly process, many mathematical models have been proposed in the literature. In particular, abstract Tile Assembly Model (aTAM) received much attention. In this work, we investigate pixel pattern generation using aTAM. For a given image, ...

  17. Coherence of light and generation of speckle patterns in photobiology and photomedicine

    Science.gov (United States)

    Zalevsky, Zeev; Belkin, Michael

    2012-03-01

    The use of diodes instead of lasers was recently suggested for phototherapeutic applications. This trend is due to economical and practical reasons and is based on the argument that lasers have no preference over diodes as light sources as the former lose their coherency upon penetrating biological tissues. This module supports this claim while providing a brief explanation to non professionals on the meaning of coherence of light as well as the physics behind the generation of speckle patterns, and the relation of these physical entities to photomedicine.

  18. Generation of accelerating Airy and accelerating parabolic beams using phase-only patterns

    OpenAIRE

    Davis, Jeffrey A.; Mitry, Mark J.; Bandres, Miguel A.; Ruiz, Isaac; McAuley, Kevin-P; Cottrell, Don M.

    2009-01-01

    We generate both accelerated Airy and accelerated parabolic beams using phase-only patterns encoded onto a liquid crystal display (LCD). The usual system length is 2f, where f is the focal length of the Fourier transform lens. We develop a compact optical system having a total system length of f. However, the mask must now incorporate the Fresnel diffraction that is not provided by the reduced optical system length. Finally we incorporate the Fourier transform lens onto the mask. We obtain ex...

  19. Fluid power network for centralized electricity generation in offshore wind farms

    Science.gov (United States)

    Jarquin-Laguna, A.

    2014-06-01

    An innovative and completely different wind-energy conversion system is studied where a centralized electricity generation within a wind farm is proposed by means of a hydraulic network. This paper presents the dynamic interaction of two turbines when they are coupled to the same hydraulic network. Due to the stochastic nature of the wind and wake interaction effects between turbines, the operating parameters (i.e. pitch angle, rotor speed) of each turbine are different. Time domain simulations, including the main turbine dynamics and laminar transient flow in pipelines, are used to evaluate the efficiency and rotor speed stability of the hydraulic system. It is shown that a passive control of the rotor speed, as proposed in previous work for a single hydraulic turbine, has strong limitations in terms of performance for more than one turbine coupled to the same hydraulic network. It is concluded that in order to connect several turbines, a passive control strategy of the rotor speed is not sufficient and a hydraulic network with constant pressure is suggested. However, a constant pressure network requires the addition of active control at the hydraulic motors and spear valves, increasing the complexity of the initial concept. Further work needs to be done to incorporate an active control strategy and evaluate the feasibility of the constant pressure hydraulic network.

  20. Central Electricity Generating Board use of operational experience feedback to assure safe designs

    International Nuclear Information System (INIS)

    Learning from experience has always been a valuable part of the engineering endeavour. Indeed, those process industries which are continually seeking improvements in their plants regard operating experience as an essential by-product of their main undertaking. When it is carefully recorded and well interpreted, operating experience can have considerable impact on the performance, availability and continuing safety of future plant designs. However, as in all other engineering activities, experience feedback must be carefully planned and executed to ensure that it is cost effective. In order to learn from experience, three things are necessary. First (and obviously) there must be previous relevant experience which has been carefully recorded and stored. Second, there must be an effective system for extracting clearly the lessons available and for targeting them on those who need to know. Third, there must be a willingness for future designers to put these lessons into practice. If any one of these three is missing, then the whole undertaking to learn from experience fails, so it is essential to pay careful attention to all three. This paper outlines how the Central Electricity Generating Board team responsible for building pressurized water reactor units is covering these three aspects. 1 ref., 5 figs

  1. Fluid power network for centralized electricity generation in offshore wind farms

    International Nuclear Information System (INIS)

    An innovative and completely different wind-energy conversion system is studied where a centralized electricity generation within a wind farm is proposed by means of a hydraulic network. This paper presents the dynamic interaction of two turbines when they are coupled to the same hydraulic network. Due to the stochastic nature of the wind and wake interaction effects between turbines, the operating parameters (i.e. pitch angle, rotor speed) of each turbine are different. Time domain simulations, including the main turbine dynamics and laminar transient flow in pipelines, are used to evaluate the efficiency and rotor speed stability of the hydraulic system. It is shown that a passive control of the rotor speed, as proposed in previous work for a single hydraulic turbine, has strong limitations in terms of performance for more than one turbine coupled to the same hydraulic network. It is concluded that in order to connect several turbines, a passive control strategy of the rotor speed is not sufficient and a hydraulic network with constant pressure is suggested. However, a constant pressure network requires the addition of active control at the hydraulic motors and spear valves, increasing the complexity of the initial concept. Further work needs to be done to incorporate an active control strategy and evaluate the feasibility of the constant pressure hydraulic network

  2. Supervised Generative Reconstruction: An Efficient Way To Flexibly Store and Recognize Patterns

    CERN Document Server

    Achler, Tsvi

    2011-01-01

    Matching animal-like flexibility in recognition and the ability to quickly incorporate new information remains difficult. Limits are yet to be adequately addressed in neural models and recognition algorithms. This work proposes a configuration for recognition that maintains the same function of conventional algorithms but avoids combinatorial problems. Feedforward recognition algorithms such as classical artificial neural networks and machine learning algorithms are known to be subject to catastrophic interference and forgetting. Modifying or learning new information (associations between patterns and labels) causes loss of previously learned information. I demonstrate using mathematical analysis how supervised generative models, with feedforward and feedback connections, can emulate feedforward algorithms yet avoid catastrophic interference and forgetting. Learned information in generative models is stored in a more intuitive form that represents the fixed points or solutions of the network and moreover disp...

  3. The internal flow pattern analysis of a tidal power turbine operating on bidirectional generation-pumping

    International Nuclear Information System (INIS)

    Using tidal energy can reduce environment pollution, save conventional energy and improve energy structure, hence it presents great advantage and is developing potential. Influenced by flood tide and low tide, a fully functional tidal power station needs to experience six operating modes, including bidirectional generation, pumping and sluice; the internal unsteady flow pattern and dynamic characters are very complicated. Based on a bidirectional tidal generator unit, three-dimensional unsteady flows in the flow path were calculated for four typical operating conditions with the pressure pulsation characteristics analyzed. According to the numerical results, the internal flow characteristics in the flow path were discussed. The influence of gravity to the hydraulic performance and flow characteristics were analysed. The results provide a theoretical analysis method of the hydraulic optimization design of the same type unit as well as a direction for stable operation and optimal scheduling of existing tidal power unit

  4. The internal flow pattern analysis of a tidal power turbine operating on bidirectional generation-pumping

    Science.gov (United States)

    Y Luo, Y.; Xiao, Y. X.; Wang, Z. W.

    2013-12-01

    Using tidal energy can reduce environment pollution, save conventional energy and improve energy structure, hence it presents great advantage and is developing potential. Influenced by flood tide and low tide, a fully functional tidal power station needs to experience six operating modes, including bidirectional generation, pumping and sluice; the internal unsteady flow pattern and dynamic characters are very complicated. Based on a bidirectional tidal generator unit, three-dimensional unsteady flows in the flow path were calculated for four typical operating conditions with the pressure pulsation characteristics analyzed. According to the numerical results, the internal flow characteristics in the flow path were discussed. The influence of gravity to the hydraulic performance and flow characteristics were analysed. The results provide a theoretical analysis method of the hydraulic optimization design of the same type unit as well as a direction for stable operation and optimal scheduling of existing tidal power unit.

  5. HIGH QUALITY IMPLEMENTATION FOR AUTOMATIC GENERATION C# CODE BY EVENT-B PATTERN

    Directory of Open Access Journals (Sweden)

    Eman K Elsayed

    2014-01-01

    Full Text Available In this paper we proposed the logical correct path to implement automatically any algorithm or model in verified C# code. Our proposal depends on using the event-B as a formal method. It is suitable solution for un-experience in programming language and profession in mathematical modeling. Our proposal also integrates requirements, codes and verification in system development life cycle. We suggest also using event-B pattern. Our suggestion is classify into two cases, the algorithm case and the model case. The benefits of our proposal are reducing the prove effort, reusability, increasing the automation degree and generate high quality code. In this paper we applied and discussed the three phases of automatic code generation philosophy on two case studies the first is “minimum algorithm” and the second one is a model for ATM.

  6. Pattern of self-medication with analgesics among Iranian University students in central Iran

    OpenAIRE

    Shadi Sarahroodi; Ali Maleki-Jamshid; Sawalha, Ansam F.; Peyman Mikaili; Leila Safaeian

    2012-01-01

    Background: Self-medication is defined as the use of drugs for the treatment of self-diagnosed disorders. It is influenced by factors such as education, family, society, law, availability of drugs and exposure to advertisements. This study was performed to evaluate self-medication with analgesics and its pattern among different groups of Iranian University Students. Materials and Methods: A randomized, cross-sectional, multicenter study was conducted from December 2009 to February 2010. The t...

  7. BEYOND GUNS AND BUTTER: Finnish Central Government Spending Patterns the in Twentieth Century

    Directory of Open Access Journals (Sweden)

    Jari Eloranta

    2008-01-01

    Full Text Available This paper explains the long-run demand for central government spending in Finland by analyzing quantitative and qualitative changes in the spending behavior, examining possible links between variables in a VAR-framework, and performing multivariate analysis of the demand factors. The results was shoved that a explained  by a lack of military versus social spending tradeoff effect. Even though certain other variables were found to be relevant in explaining this demand, this lack of a tradeoff increased the Finnish spending levels substantially during the twentieth centurt welfare state expansion.

  8. Mortality pattern of the surrounding population of the Central Nuclear Almirante Alvaro Alberto / 1986 to 2007

    International Nuclear Information System (INIS)

    This paper aims to update two earlier epidemiological studies on the mortality profile of the resident population in the influence area of the Central Nuclear Almirante Alvaro Alberto. The main objective is analyze and compare the profile of mortality among the population classified in areas with the distance from source of exposure in three strata. Municipalities contained within a radius of 30 km of the nuclear power, neighboring municipalities, contained within a radius of 30 to 50 km, municipalities contained within 50 to 100 km, beyond Cabo Frio, which presents similar characteristics to the municipality of Angra dos Reis

  9. Low frequency variability of European weather patterns and its impact on power generation in northern Europe

    Science.gov (United States)

    Masato, Giacomo; Slavov, Georgi

    2016-04-01

    It is well known that Europe is becoming increasingly reliant on the power generation from the solar and wind sources. Germany is a leader in such a trend - it is then interesting to study to what extent the low-frequency variability of the European weather patterns impacts the power production in this country. Rather than identifying such patterns starting from the weather angle, four weather regimes are identified that maximize and minimize the production of solar and wind power. The analysis of their past occurrence and trends allows us to estimate the potential amount of energy produced for any given year (assuming a constant installed capacity). It is found that the sole change in such weather regimes over the recent years is able to drive up to a 20% annual difference in power generation. This also throws an interesting challenge at the scientific community, whereby the future projection of these regimes can heavily influence both the short- and long-term Eurozone plans in terms of European renewable energy targets.

  10. Pattern of Maxillofacial fracture in Western and Central Nepal: An experience in 3 tertiary level health institutions

    Directory of Open Access Journals (Sweden)

    S Subedi

    2015-06-01

    Full Text Available BACKGROUND: There are only few studies regarding the pattern and causes of maxillofacial fractures till date in Nepal and no such study in western and central Nepalese population has been conducted. The purpose of this study, therefore, was to describe the causes and the pattern of maxillofacial fractures in western and central part of Nepal over the period of 5 years. MATERIAL AND METHODS A retrospective analysis of maxillofacial fractures was conducted on 328 patients who were treated in the department of maxillofacial surgery. Data was extracted and analyzed based on age, sex, cause of injury and anatomic location. RESULT Young males of 3rd decade of life most commonly sustained the maxillofacial trauma. The commonest site involved was the zygomatic complex (42% when only mid face fractures was considered and parasymphysis (32% when only mandible was considered.The most common cause of injuries was road traffic accidents (289 patients; 88.1% followed by interpersonal violence (25 patients; 7.6 % and falls accounting for 4.2% of the all injuries. CONCLUSION The findings of this study suggest the need for expansion of the motorway network, ensuring compliance of strict traffic rules and regulations, replacing old vehicles without safety measures and implement school education in alcohol abuse.DOI: http://dx.doi.org/10.3126/jcmsn.v10i3.12771 Journal of College of Medical Sciences-Nepal, 2014, Vol-10, No-3, 8-13

  11. Burden & pattern of illnesses among the tribal communities in central India : A report from a community health programme.

    Science.gov (United States)

    Jain, Yogesh; Kataria, Raman; Patil, Sushil; Kadam, Suhas; Kataria, Anju; Jain, Rachna; Kurbude, Ravindra; Shinde, Sharayu

    2015-05-01

    Tribals are the most marginalised social category in the country and there is little and scattered information on the actual burden and pattern of illnesses they suffer from. This study provides information on burden and pattern of diseases among tribals, and whether these can be linked to their nutritional status, especially in particularly vulnerable tribal groups (PVTG) seen at a community health programme being run in the tribal areas of Chhattisgarh and Madhya Pradesh States of India. This community based programme, known as Jan Swasthya Sahyog (JSS) has been serving people in over 2500 villages in rural central India. It was found that the tribals had significantly higher proportion of all tuberculosis, sputum positive tuberculosis, severe hypertension, illnesses that require major surgery as a primary therapeutic intervention and cancers than non tribals. The proportions of people with rheumatic heart disease, sickle cell disease and epilepsy were not significantly different between different social groups. Nutritional levels of tribals were poor. Tribals in central India suffer a disproportionate burden of both communicable and non communicable diseases amidst worrisome levels of undernutrition. There is a need for universal health coverage with preferential care for the tribals, especially those belonging to the PVTG. Further, the high level of undernutrition demands a more augmented and universal Public Distribution System. PMID:26139787

  12. Resolution Improvement and Pattern Generator Development for the Maskless Micro-Ion-Beam Reduction Lithography System

    International Nuclear Information System (INIS)

    have been studied. The dependence of the throughput with the exposure field size and the speed of the mechanical stage has been investigated. In order to perform maskless lithography, different micro-fabricated pattern generators have been developed for the MMRL system. Ion beamlet switching has been successfully demonstrated on the MMRL system. A positive bias voltage around 10 volts is sufficient to switch off the ion current on the micro-fabricated pattern generators. Some unexpected problems, such as the high-energy secondary electron radiations, have been discovered during the experimental investigation. Thermal and structural analysis indicates that the aperture displacement error induced by thermal expansion can satisfy the 3(delta) CD requirement for lithography nodes down to 25 nm. The cross-talking effect near the surface and inside the apertures of the pattern generator has been simulated in a 3-D ray-tracing code. New pattern generator design has been proposed to reduce the cross-talking effect. In order to eliminate the surface charging effect caused by the secondary electrons, a new beam-switching scheme in which the switching electrodes are immersed in the plasma has been demonstrated on a mechanically fabricated pattern generator

  13. A RANDOM FUNCTIONAL CENTRAL LIMIT THEOREM FOR PROCESSES OF PRODUCT SUMS OF LINEAR PROCESSES GENERATED BY MARTINGALE DIFFERENCES

    Institute of Scientific and Technical Information of China (English)

    WANG YUEBAO; YANG YANG; ZHOU HAIYANG

    2003-01-01

    A random functional central limit theorem is obtained for processes of partial sums andproduct sums of linear processes generated by non-stationary martingale differences. It devel-ops and improves some corresponding results on processes of partial sums of linear processesgenerated by strictly stationary martingale differences, which can be found in [5].

  14. Association between atmospheric circulation patterns and firn-ice core records from the Inilchek glacierized area, central Tien Shan, Asia

    Science.gov (United States)

    Aizen, V.B.; Aizen, E.M.; Melack, J.M.; Kreutz, K.J.; Cecil, L.D.

    2004-01-01

    Glacioclimatological research in the central Tien Shan was performed in the summers of 1998 and 1999 on the South Inilchek Glacier at 5100-5460 m. A 14.36 m firn-ice core and snow samples were collected and used for stratigraphic, isotopic, and chemical analyses. The firn-ice core and snow records were related to snow pit measurements at an event scale and to meteorological data and synoptic indices of atmospheric circulation at annual and seasonal scales. Linear relationships between the seasonal air temperature and seasonal isotopic composition in accumulated precipitation were established. Changes in the ??18O air temperature relationship, in major ion concentration and in the ratios between chemical species, were used to identify different sources of moisture and investigate changes in atmospheric circulation patterns. Precipitation over the central Tien Shan is characterized by the lowest ionic content among the Tien Shan glaciers and indicates its mainly marine origin. In seasons of minimum precipitation, autumn and winter, water vapor was derived from the and and semiarid regions in central Eurasia and contributed annual maximal solute content to snow accumulation in Tien Shan. The lowest content of major ions was observed in spring and summer layers, which represent maximum seasonal accumulation when moisture originates over the Atlantic Ocean and Mediterranean and Black Seas. Copyright 2004 by the American Geophysical Union.

  15. Differential roles for EphA and EphB signaling in segregation and patterning of central vestibulocochlear nerve projections.

    Directory of Open Access Journals (Sweden)

    Michelle R Allen-Sharpley

    Full Text Available Auditory and vestibular afferents enter the brainstem through the VIIIth cranial nerve and find targets in distinct brain regions. We previously reported that the axon guidance molecules EphA4 and EphB2 have largely complementary expression patterns in the developing avian VIIIth nerve. Here, we tested whether inhibition of Eph signaling alters central targeting of VIIIth nerve axons. We first identified the central compartments through which auditory and vestibular axons travel. We then manipulated Eph-ephrin signaling using pharmacological inhibition of Eph receptors and in ovo electroporation to misexpress EphA4 and EphB2. Anterograde labeling of auditory afferents showed that inhibition of Eph signaling did not misroute axons to non-auditory target regions. Similarly, we did not find vestibular axons within auditory projection regions. However, we found that pharmacologic inhibition of Eph receptors reduced the volume of the vestibular projection compartment. Inhibition of EphB signaling alone did not affect auditory or vestibular central projection volumes, but it significantly increased the area of the auditory sensory epithelium. Misexpression of EphA4 and EphB2 in VIIIth nerve axons resulted in a significant shift of dorsoventral spacing between the axon tracts, suggesting a cell-autonomous role for the partitioning of projection areas along this axis. Cochlear ganglion volumes did not differ among treatment groups, indicating the changes seen were not due to a gain or loss of cochlear ganglion cells. These results suggest that Eph-ephrin signaling does not specify auditory versus vestibular targets but rather contributes to formation of boundaries for patterning of inner ear projections in the hindbrain.

  16. Reproduction pattern of “gading starling” (Turdus sp.) at Mount Lawu, Central Java

    OpenAIRE

    AGUNG BUDIHARJO

    2005-01-01

    The aim of the research was to know reproduction pattern of “gading starling” (Turdus sp.) in natural habitat, namely Mount Lawu. This research was expected to give accurate information that can be used as base of conservation effort. Research had been done alongside of Cemoro Sewu tracking line. Data was collected at 2600, 2800, 3000, 3100, and 3200 m. asl., in March, April, May, and October 2004. Nesting observation was concerning with nest place at tree, height of ground surface, apart fro...

  17. Permission of change of limits in the vapor generators of the Atucha I Nuclear Central

    International Nuclear Information System (INIS)

    In the mark of the modification of the Atucha-I Nuclear Central Installation (CNA-I) as consequence of the Introduction of the System 'Second Drain of Heat' (SSC), the Entity Responsible for the CNA-I (NASA) requested authorization to the Nuclear Regulatory Authority (ARN) to modify the value of the minimum level of water in the secondary side in the Steam generators (GVs) to activate the signal 'shoot of the Cut of the Reactor' (RESA-LLV). As the level in the GVs is one of those parameters that are used to shoot the Emergency Feeding System (RX), component of the SSC System, also was analyzed the change in the activation of the shoot signal of the 'Second Drain of Heat' (2SSC-LLV). The ARN uses for the study of the nuclear safety of nuclear power plants, the series of prediction programs RELAP5/MOD3.X. It participates of the evaluation and maintenance activities of these codes through specific agreements with the U.S. Nuclear Regulatory Commission (US-NRC). It is necessary to account with programs of this type since the ARN it licenses the construction and operation of Nuclear Power Plants (NPPs) and other outstanding facilities and it inquires its operation according to its own standards. With these tools its are auditing the calculations that the Responsible Entities of the operation make to guarantee the operability of the NPPs assisting the mentioned standards. The analysis with computational codes is used as a tool to achieve the best understanding in the behavior of the plant in union with the engineering approach, the manual calculations, the data analysis and the experience in the operation of the machine. (Author)

  18. Injector for a high frequency wave generating tube of the central injection Gyrotron type

    International Nuclear Information System (INIS)

    This theoretical and at the same time experimental study was carried out at the 'Service Ionique Generale' in Grenoble. High frequency wave generators are already in use there, making it possible to approach the fusion conditions of light elements such as deuterium. The plasma confined by the toroidal magnetic field uses to heat itself the electromagnetic energy provided by sources from which a good performance is required. Klystron and Magnetron are devices in which the interaction between the electric and magnetic fields of a resonating cavity and the continuous energy of a beam produces a positive result. In the Klystron, the velocity modulation is axial whereas in the Magnetron it is azimuthal. Therefore packets of electrons are formed. If this modulation of the velocities occurs radially, the beam will swell and compress periodically. The name of 'Central Injection Gyrotron' has been associated recently in the literature to this type of interaction exhibiting a good performance. Placing on trajectory the electrons forming the beam is one of the difficulties of the good working of this ultra high frenquency tube. Since no device gives safisfaction at the present time, the devising of a new type of injector specially adapted to the forming of the beam is therefore justified. The originality is that it uses on the electrostatic gun side a cathode immersed in a magnetic field of which the axial component is in the opposite direction to that which maintains the formed beam injected in the cavity. The magnetic correction of the trajectories is the most practical with respect to the experiment, providing that the electrostatic gun does not disperse them individually. This leads to seeking an improvement in the geometry of the gun. However, it will be necessary to consider the problems of power limitation due to the space charge

  19. Spatial pattern and weight of seabed marine litter in the northern and central Adriatic Sea.

    Science.gov (United States)

    Strafella, P; Fabi, G; Spagnolo, A; Grati, F; Polidori, P; Punzo, E; Fortibuoni, T; Marceta, B; Raicevich, S; Cvitkovic, I; Despalatovic, M; Scarcella, G

    2015-02-15

    The present study analyzes spatial distribution and typology of marine litter on the seabed in the FAO Geographical Sub-Area 17 (northern and central Adriatic Sea). Two surveys were conducted during fall 2011 and 2012 and 67 stations were sampled each year. Litter items were collected using the "rapido" trawl, a modified beam trawl commonly used by the Italian fishermen to catch flat fish and other benthic species. Marine litter in the catches was sorted and classified in 6 major categories (plastic, metal, glass, rubber, wood, other). Plastic litter was further subdivided in 3 sub-categories based on its source: fishing nets, aquaculture nets and other. Plastic was dominant in terms of weight followed by metal and other categories. The highest concentration of litter was found close to the coast likely as a consequence of high coastal urbanization, river inflow and extensive navigation associated with the morphological and hydrological features of the basin. PMID:25560999

  20. Extent and pattern of paediatric dermatoses in rural areas of central India

    Directory of Open Access Journals (Sweden)

    Bhatia Vikas

    1997-01-01

    Full Text Available A house to house study was done on 666 children aged 0-14 years in 5 villages of Wardha district in Maharastra (Central India. 346 children (51.95% had one or more dermatoses. Infective dermatoses contributed 63.5% of all dermatoses, while noninfectious and nutritional deficiency dermatoses were responsibile for 21.2% and 15.2%, respectively. Pediculosis capitis was seen in 136 children (20.4%, followed by pyoderma in 107 (16.07% and dematophytosis in 44 (6.61%. Scabies was found in only 6 and 4 cases of leprosy were also delected. Pityriasis alba, pityriasis capitis amond non-infectious; hair and skin changes among nutritional deficiency dermatoses were leading presentations.

  1. Patterns and drivers of phytodiversity in steppe grasslands of Central Podolia (Ukraine)

    DEFF Research Database (Denmark)

    Kuzemko, Anna; Steinbauer, Manuel; Becker, Thomas; Didukh, Yakiv; Dolnik, Christian; Jeschke, Michael; Naqinezhad, Alireza; Ugurlu, Emin; Vassilev, Kiril; Dengler, Jürgen

    2016-01-01

    We asked: (i) Which environmental factors determine the level of α-diversity at several scales and β-diversity in steppic grasslands? (ii) How do the effects of environmental factors on α- and β-diversity vary between the different taxonomic groups (vascular plants, bryophytes, lichens)? We sampled...... nested-plot series ranging from 0.0001 to 100 m2 and additional 10-m2 plots, covering different vegetation types and management regimes in steppes and semi-natural dry grasslands of Central Podolia (Ukraine). We recorded all terricolous taxa and used topographic, soil, land-use and climatic variables as...... intermediate compared to those known from similar grasslands throughout the Palaearctic, but for 1 cm2 we found seven species of vascular plants, a new world record. Heat index was the most important factor for vascular plants and bryophytes (negative relation), while lichen diversity depended mainly on stone...

  2. Habitat use and foraging patterns of molting male Long-tailed Ducks in lagoons of the central Beaufort Sea, Alaska

    Science.gov (United States)

    Flint, Paul L.; Reed, John; Deborah Lacroix; Richard Lanctot

    2016-01-01

    From mid-July through September, 10 000 to 30 000 Long-tailed Ducks (Clangula hyemalis) use the lagoon systems of the central Beaufort Sea for remigial molt. Little is known about their foraging behavior and patterns of habitat use during this flightless period. We used radio transmitters to track male Long-tailed Ducks through the molt period from 2000 to 2002 in three lagoons: one adjacent to industrial oil field development and activity and two in areas without industrial activity. We found that an index to time spent foraging generally increased through the molt period. Foraging, habitat use, and home range size showed similar patterns, but those patterns were highly variable among lagoons and across years. Even with continuous daylight during the study period, birds tended to use offshore areas during the day for feeding and roosted in protected nearshore waters at night. We suspect that variability in behaviors associated with foraging, habitat use, and home range size are likely influenced by availability of invertebrate prey. Proximity to oil field activity did not appear to affect foraging behaviors of molting Long-tailed Ducks.

  3. Congruent phylogeographical patterns of eight tree species in Atlantic Central Africa provide insights into the past dynamics of forest cover.

    Science.gov (United States)

    Dauby, G; Duminil, J; Heuertz, M; Koffi, G K; Stévart, T; Hardy, O J

    2014-05-01

    Cycles of Quaternary climatic change are assumed to be major drivers of African rainforest dynamics and evolution. However, most hypotheses on past vegetation dynamics relied on palaeobotanical records, an approach lacking spatial resolution, and on current patterns of species diversity and endemism, an approach confounding history and environmental determinism. In this context, a comparative phylogeographical study of rainforest species represents a complementary approach because Pleistocene climatic fluctuations may have left interpretable signatures in the patterns of genetic diversity within species. Using 1274 plastid DNA sequences from eight tree species (Afrostyrax kamerunensis, A. lepidophyllus, Erythrophleum suaveolens, Greenwayodendron suaveolens, Milicia excelsa, Santiria trimera, Scorodophloeus zenkeri and Symphonia globulifera) sampled in 50 populations of Atlantic Central Africa (ACA), we averaged divergence across species to produce the first map of the region synthesizing genetic distinctiveness and standardized divergence within and among localities. Significant congruence in divergence was detected mostly among five of the eight species and was stronger in the northern ACA. This pattern is compatible with a scenario of past forest fragmentation and recolonization whereby forests from eastern Cameroon and northeastern Gabon would have been more affected by past climatic change than those of western Cameroon (where one or more refugia would have occurred). By contrast, southern ACA (Gabon) displayed low congruence among species that may reflect less drastic past forest fragmentation or a more complex history of vegetation changes. Finally, we also highlight the potential impact of current environmental barriers on spatial genetic structures. PMID:24655106

  4. Optimisation of a Kalina cycle for a central receiver solar thermal power plant with direct steam generation

    DEFF Research Database (Denmark)

    Modi, Anish; Haglind, Fredrik

    2014-01-01

    Central receiver solar thermal power plants are regarded as one of the promising ways to generate electricity in near future. They offer the possibility of using high temperatures and pressures to achieve high efficiencies with standard power cycles. A direct steam generation approach can be used...... for a central receiver solar thermal power plant with direct steam generation. The variation in the cycle performance with respect to the turbine inlet ammonia mass fraction and pressure and a comparison of the initial investment with that of the basic Rankine cycle are also presented. Only high live steam...... for such plants for improved performance. This approach can also be combined with using advanced power cycles like the Kalina cycle, which uses a zeotropic mixture of ammonia and water instead of pure water as the working fluid. This paper presents the optimisation of a particular Kalina cycle layout...

  5. Comparison of the reliability of multifocal visual evoked cortical potentials generated by pattern reversal and pattern pulse stimulation

    OpenAIRE

    G.S. Souza; H.B. Schakelford; Moura, A.L.A.; Gomes, B.D.; D.F. Ventura; M.E.C. Fitzgerald; L.C.L. Silveira

    2012-01-01

    This study compared the effectiveness of the multifocal visual evoked cortical potentials (mfVEP) elicited by pattern pulse stimulation with that of pattern reversal in producing reliable responses (signal-to-noise ratio >1.359). Participants were 14 healthy subjects. Visual stimulation was obtained using a 60-sector dartboard display consisting of 6 concentric rings presented in either pulse or reversal mode. Each sector, consisting of 16 checks at 99% Michelson contrast and 80 cd/m² mean lu...

  6. Patterns of children's growth in east-central Europe in the eighteenth century.

    Science.gov (United States)

    Komlos, J

    1986-01-01

    Records in Vienna of the heights of (a) Military Academy youths born between 1730 and 1760, (b) orphanage children born between 1760 and 1780 and (c) military boarding-school children born between 1775 and 1815 have been retrieved and analysed. This constitutes the earliest extant set of measurements of the heights of a group of individuals. Stature was increasing in the late 1740s and decreasing after the 1770s. This evidence indicates a rise and subsequent fall in nutritional status and is consistent with the known pattern of European agricultural conditions in the eighteenth century. Shifts in the age of maximum increment support the notion of the secular changes in the nutritional status of these boys. The stature of the Habsburg boys was greater than the poorest boys of contemporary London but compared unfavourably with the height of the English gentry and American cadets of the nineteenth century and, of course, with the height of today's populations. PMID:3516059

  7. "GAG-ing with the neuron": The role of glycosaminoglycan patterning in the central nervous system.

    Science.gov (United States)

    Smith, Patrice D; Coulson-Thomas, Vivien J; Foscarin, Simona; Kwok, Jessica C F; Fawcett, James W

    2015-12-01

    Proteoglycans (PGs) are a diverse family of proteins that consist of one or more glycosaminoglycan (GAG) chains, covalently linked to a core protein. PGs are major components of the extracellular matrix (ECM) and play critical roles in development, normal function and damage-response of the central nervous system (CNS). GAGs are classified based on their disaccharide subunits, into the following major groups: chondroitin sulfate (CS), heparan sulfate (HS), heparin (HEP), dermatan sulfate (DS), keratan sulfate (KS) and hyaluronic acid (HA). All except HA are modified by sulfation, giving GAG chains specific charged structures and binding properties. While significant neuroscience research has focused on the role of one PG family member, chondroitin sulfate proteoglycan (CSPG), there is ample evidence in support of a role for the other PGs in regulating CNS function in normal and pathological conditions. This review discusses the role of all the identified PG family members (CS, HS, HEP, DS, KS and HA) in normal CNS function and in the context of pathology. Understanding the pleiotropic roles of these molecules in the CNS may open the door to novel therapeutic strategies for a number of neurological conditions. PMID:26277685

  8. Pattern and determinants of morbidity among people living with HIV/AIDS in North Central Nigeria.

    Science.gov (United States)

    Olaleye, Adeniyi; Ogwumike, F O

    2013-02-01

    The study investigated the nature of self-reported morbidity and determinants of health status among people living with HIV/AIDS (PLWHA) in North Central Nigeria. A multi-stage cluster sampling method was used to select 1,056 adult PLWHA from 60 community-based support groups as respondents to a structured questionnaire. Based on health production function, health status was specified as a function of individual/household characteristics, health-related behaviours and genetic endowment. Descriptive statistics showed that more than half (52.8%, n=558) of the PLWHA reported illness in the last four weeks. The poor, widows and divorcees, and those living in rural areas reported illness more than their non-poor, married and urban counterparts. Logistic regression results indicated that self reported mobility was associated with rural residence (p=.005), greater use of condom (p=.013), and lower CD4 count (p=.007). Programs to promote positive living and access to health care services among PLWHA in Nigeria, especially in rural areas, are recommended. PMID:23377732

  9. Spatial pattern and weight of seabed marine litter in the northern and central Adriatic Sea

    International Nuclear Information System (INIS)

    Highlights: • First assessment of marine litter distribution on the seabed of GSA 17. • The manuscript depicts the status of marine litter on a regional scale. • Maps are produced either for the overall litter and for the main litter categories. • The study identifies the possible sources of some litter items. • The results constitute a starting step for marine litter monitoring in the area. - Abstract: The present study analyzes spatial distribution and typology of marine litter on the seabed in the FAO Geographical Sub-Area 17 (northern and central Adriatic Sea). Two surveys were conducted during fall 2011 and 2012 and 67 stations were sampled each year. Litter items were collected using the “rapido” trawl, a modified beam trawl commonly used by the Italian fishermen to catch flat fish and other benthic species. Marine litter in the catches was sorted and classified in 6 major categories (plastic, metal, glass, rubber, wood, other). Plastic litter was further subdivided in 3 sub-categories based on its source: fishing nets, aquaculture nets and other. Plastic was dominant in terms of weight followed by metal and other categories. The highest concentration of litter was found close to the coast likely as a consequence of high coastal urbanization, river inflow and extensive navigation associated with the morphological and hydrological features of the basin

  10. Spatiotemporal patterns of fault slip rates across the Central Sierra Nevada frontal fault zone

    Science.gov (United States)

    Rood, Dylan H.; Burbank, Douglas W.; Finkel, Robert C.

    2011-01-01

    Patterns in fault slip rates through time and space are examined across the transition from the Sierra Nevada to the Eastern California Shear Zone-Walker Lane belt. At each of four sites along the eastern Sierra Nevada frontal fault zone between 38 and 39° N latitude, geomorphic markers, such as glacial moraines and outwash terraces, are displaced by a suite of range-front normal faults. Using geomorphic mapping, surveying, and 10Be surface exposure dating, mean fault slip rates are defined, and by utilizing markers of different ages (generally, ~ 20 ka and ~ 150 ka), rates through time and interactions among multiple faults are examined over 10 4-10 5 year timescales. At each site for which data are available for the last ~ 150 ky, mean slip rates across the Sierra Nevada frontal fault zone have probably not varied by more than a factor of two over time spans equal to half of the total time interval (~ 20 ky and ~ 150 ky timescales): 0.3 ± 0.1 mm year - 1 (mode and 95% CI) at both Buckeye Creek in the Bridgeport basin and Sonora Junction; and 0.4 + 0.3/-0.1 mm year - 1 along the West Fork of the Carson River at Woodfords. Data permit rates that are relatively constant over the time scales examined. In contrast, slip rates are highly variable in space over the last ~ 20 ky. Slip rates decrease by a factor of 3-5 northward over a distance of ~ 20 km between the northern Mono Basin (1.3 + 0.6/-0.3 mm year - 1 at Lundy Canyon site) to the Bridgeport Basin (0.3 ± 0.1 mm year - 1 ). The 3-fold decrease in the slip rate on the Sierra Nevada frontal fault zone northward from Mono Basin is indicative of a change in the character of faulting north of the Mina Deflection as extension is transferred eastward onto normal faults between the Sierra Nevada and Walker Lane belt. A compilation of regional deformation rates reveals that the spatial pattern of extension rates changes along strike of the Eastern California Shear Zone-Walker Lane belt. South of the Mina Deflection

  11. Diet-related buccal dental microwear patterns in Central African Pygmy foragers and Bantu-speaking farmer and pastoralist populations.

    Science.gov (United States)

    Romero, Alejandro; Ramírez-Rozzi, Fernando V; De Juan, Joaquín; Pérez-Pérez, Alejandro

    2013-01-01

    Pygmy hunter-gatherers from Central Africa have shared a network of socioeconomic interactions with non-Pygmy Bantu speakers since agropastoral lifestyle spread across sub-Saharan Africa. Ethnographic studies have reported that their diets differ in consumption of both animal proteins and starch grains. Hunted meat and gathered plant foods, especially underground storage organs (USOs), are dietary staples for pygmies. However, scarce information exists about forager-farmer interaction and the agricultural products used by pygmies. Since the effects of dietary preferences on teeth in modern and past pygmies remain unknown, we explored dietary history through quantitative analysis of buccal microwear on cheek teeth in well-documented Baka pygmies. We then determined if microwear patterns differ among other Pygmy groups (Aka, Mbuti, and Babongo) and between Bantu-speaking farmer and pastoralist populations from past centuries. The buccal dental microwear patterns of Pygmy hunter-gatherers and non-Pygmy Bantu pastoralists show lower scratch densities, indicative of diets more intensively based on nonabrasive foodstuffs, compared with Bantu farmers, who consume larger amounts of grit from stoneground foods. The Baka pygmies showed microwear patterns similar to those of ancient Aka and Mbuti, suggesting that the mechanical properties of their preferred diets have not significantly changed through time. In contrast, Babongo pygmies showed scratch densities and lengths similar to those of the farmers, consistent with sociocultural contacts and genetic factors. Our findings support that buccal microwear patterns predict dietary habits independent of ecological conditions and reflect the abrasive properties of preferred or fallback foods such as USOs, which may have contributed to the dietary specializations of ancient human populations. PMID:24367696

  12. Diet-related buccal dental microwear patterns in Central African Pygmy foragers and Bantu-speaking farmer and pastoralist populations.

    Directory of Open Access Journals (Sweden)

    Alejandro Romero

    Full Text Available Pygmy hunter-gatherers from Central Africa have shared a network of socioeconomic interactions with non-Pygmy Bantu speakers since agropastoral lifestyle spread across sub-Saharan Africa. Ethnographic studies have reported that their diets differ in consumption of both animal proteins and starch grains. Hunted meat and gathered plant foods, especially underground storage organs (USOs, are dietary staples for pygmies. However, scarce information exists about forager-farmer interaction and the agricultural products used by pygmies. Since the effects of dietary preferences on teeth in modern and past pygmies remain unknown, we explored dietary history through quantitative analysis of buccal microwear on cheek teeth in well-documented Baka pygmies. We then determined if microwear patterns differ among other Pygmy groups (Aka, Mbuti, and Babongo and between Bantu-speaking farmer and pastoralist populations from past centuries. The buccal dental microwear patterns of Pygmy hunter-gatherers and non-Pygmy Bantu pastoralists show lower scratch densities, indicative of diets more intensively based on nonabrasive foodstuffs, compared with Bantu farmers, who consume larger amounts of grit from stoneground foods. The Baka pygmies showed microwear patterns similar to those of ancient Aka and Mbuti, suggesting that the mechanical properties of their preferred diets have not significantly changed through time. In contrast, Babongo pygmies showed scratch densities and lengths similar to those of the farmers, consistent with sociocultural contacts and genetic factors. Our findings support that buccal microwear patterns predict dietary habits independent of ecological conditions and reflect the abrasive properties of preferred or fallback foods such as USOs, which may have contributed to the dietary specializations of ancient human populations.

  13. A new Pulse-Pattern Generator based on LabVIEW FPGA

    International Nuclear Information System (INIS)

    For the control of experimental sequences composed of triggers, gates and delays a Pulse-Pattern Generator (PPG) has been developed based on a Field Programmable Gate Array (FPGA) addressed in a LabVIEW environment. It allows a highly reproducible timing of measurement procedures by up to 64 individual channels with pulse and delay periods from the nanoseconds to the minutes range. The PPG has been implemented in the context of the development of a new control system for the ClusterTrap setup, an ion storage device for atomic-cluster research, in close contact with the SHIPTRAP and ISOLTRAP collaborations at GSI and CERN, respectively. As the new PPG is not ion-trap specific it can be employed in any experiment based on sequences of triggers, pulses and delays.

  14. Anthropogenic and Geologic Influence on the Downstream Fining Pattern of the Cosumnes River, Central Valley, California

    Science.gov (United States)

    Fehr, C. R.; Mount, J. F.

    2001-05-01

    A geomorphic survey of the Cosumnes River was conducted to identify the effects of anthropogenic change and local geology on downstream changes in grain size. Patterns of downstream fining exhibited by alluvial rivers reflect the processes of abrasion and sediment sorting by selective entrainment, transport and deposition. Longitudinal sorting of gravel is commonly modeled as a downstream exponential decrease in median particle grain size over the length of the profile. This relationship mirrors downstream reduction in gradient and bed shear stress typical of aggrading alluvial channels and is influenced by variations in sediment supply. The impacts of anthropogenic activity on these variables should be reflected by departures in downstream fining patterns from the expected trend. Results from this study show that grain-size change over the longitudinal profile deviates significantly from the predicted model. In addition, grain-size measurements at cross-sections demonstrate poor correlation with average bankfull bed shear stress. At sites where grain size appears unrelated to distance downstream as well as to energy slope, sediment transport may be directly influenced by alterations to the channel such as in-stream mining and the construction of diversion dams. Fluvial response to the cumulative effects of watershed-scale anthropogenic activities has also contributed to the modification of the nature of sediment transport in the channel. Prior to settlement of the Great Valley, the Cosumnes was a shallow, anastomosing alluvial river connected to a broad floodplain. Changes in land-use practices as well as channel regulation have caused rapid river-bed degradation and incision into resistant Quaternary alluvial fan deposits in some locations. Unlike the alluvial reaches studied, those with duripan beds and banks are characterized by a step-pool-like structure and contribute only small volumes of coarse sediment to the river. Data suggest that sediment transport in

  15. A New Generation Technique for Stiffener Layout Pattern to Attain Vibration-proof Plate

    International Nuclear Information System (INIS)

    A new and effective generation technique of stiffener layout pattern for thin stiffened plates to attain vibration-proof structure, based on the growing and branching tree model, is suggested in this paper. The technique starts from seeds, positions of which are specified in advance, and grows the stiffeners around seeds. Each stiffener extends by obeying the growing and branching rules like trees. The potential ability of branching will be assigned to the stiffeners, cross sectional area of which is greater than the specified threshold dimension. And the best growing direction of branch is selected depending on the effect of extension of a new branch. During the growing process of stiffener, the volume growth rate is controlled so as to be possible to create new branches and to eliminate degenerated ones. The growing process will stop when the stiffener volume reaches the given upper limit. Simulations of some typical stiffener design examples are implemented to prove the validity and effectiveness of the proposed method, and optimal patterns of stiffener layout for some plate with different geometric shapes and support conditions are demonstrated

  16. Automatic test pattern generation for stuck-at and delay faults in combinational circuits

    International Nuclear Information System (INIS)

    The present studies are developed to propose the automatic test pattern generation (ATG) algorithms for combinational circuits. These ATG algorithms are realized in two ATG programs: One is the ATG program for stuck-at fault and the other one for delay faults. In order to accelerate the ATG process, these two ATG programs have a common feature (the search method based on the concept of the degree of freedom), whereas only ATG program for the delay fault utilizes the 19-valued logic, a type of composite valued logic. This difference between two ATG programs results from the difference of the target fault. Accelerating the ATG process is indispensable for improving the ATG algorithms. This acceleration is mainly achieved by reducing the number of the unnecessary backtrackings, making the earlier detection of the conflicts, and shortening the computation time between the implication. Because of this purpose, the developed ATG programs include the new search method based on the concept of the degree of freedom (DF). The DF concept, computed directly and easily from the system descriptions such as types of gates and their interconnections, is the criterion to decide which, among several alternate lines' logic values required along each path, promises to be the most effective in order to accelerate and improve the ATG process. This DF concept is utilized to develop and improve both of ATG programs for stuck-at and delay faults in combinational circuits. In addition to improving the ATG process, reducing number of test pattern is indispensable for testing the delay faults because the size of the delay faults grows rapidly as increasing the size of the circuit. In order to improve the compactness of the test set, 19-valued logic are derived. Unlike other TG logic systems, 19-valued logic is utilized to generate the robustly hazard-free test pattern. This is achieved by using the basic 5-valued logic, proposed in this work, where the transition with no hazard is

  17. Pattern of self-medication with analgesics among Iranian University students in central Iran

    Directory of Open Access Journals (Sweden)

    Shadi Sarahroodi

    2012-01-01

    Full Text Available Background: Self-medication is defined as the use of drugs for the treatment of self-diagnosed disorders. It is influenced by factors such as education, family, society, law, availability of drugs and exposure to advertisements. This study was performed to evaluate self-medication with analgesics and its pattern among different groups of Iranian University Students. Materials and Methods: A randomized, cross-sectional, multicenter study was conducted from December 2009 to February 2010. The target population of this study was 564 students out of 10,000 students attending four medical and non-medical science universities in Qom state. Data was analyzed using SPSS version 16, and analysis was conducted with descriptive analysis procedures. Results: 76.6% of the students had used analgesics in self-medication in the previous 3 months. The frequency of analgesic use in the study period was once in 19.2% of the participants, twice in 22.2%, three times in 16.3% and more than three times in 35.5% of the participants, although 6.8% of them were not sure when they were used. Of all the respondents, 49.8% reported headache as the problem. This was the most common problem, after which came Dysmenorrhea,headache and stomach ache. Bone and joint pains were other problems that led to the use of analgesics. The most commonly used source of information for self-medication with analgesics was advice from friends and family (54.7%, previously prescribed medications (30.1%, their medical knowledge (13.3% and recommendation of a pharmacist (1.9%. Conclusion: Self-medication with analgesics is very high among Iranian students in Qom city. This could be an index for other parts of the Iranian community. Because the source of information about analgesics is inappropriate, we would recommend education courses about analgesics and self-medication on the radio and television for the entire population.

  18. Pattern of obstetrics complication among pregnant females admitted in a tertiary care centre in central India

    Directory of Open Access Journals (Sweden)

    Manik S. Shirpurkar

    2015-04-01

    Background: About half a million women die every year of causes related to pregnancy and child birth. Complication can arise at any time during pregnancy; child birth and post natal period and in absence of intervention, there is a high feto - maternal morbidity and mortality. Aim:- To study the pattern of obstetrics complication among antenatal patients coming to a tertiary care centre. Material and Methods:- A cross sectional study was conducted among 102 antenatal women admitted in intensive care unit of our institute during July 2014 to November 2014. Data regarding maternal socio-demographic profile and antenatal profile was collected. Result:- Out of total 102 women included in the study. 95(93% were registered and 7 were unregistered women. 88(86.4% women had 3 or more antenatal visit, of which 3(2.9% were unregistered women. 82(80.3% women had blood Hb% <11; of which 7 (6.8% were unregistered women. Out of total 102 women, 64(62.7% women were having complications related to abnormal labour; 34(33.3% obstetrical disorder, 21(20.5% Hypertensive disorder. Because of multi-disciplinary team approach at our institute, no maternal mortality was reported among the antenatal women admitted during this period in our institute. Conclusion:- All women need access to antenatal care; institutional delivery and post partum care. Complication arises at any time in absence of intervention. Multidisciplinary team approach along with intensive care specialist and anaesthesiologists can bring optimum care and thereby help in reducing maternal mortality. [Int J Reprod Contracept Obstet Gynecol 2015; 4(2.000: 338-343

  19. The tree water isoscape of a central Pennsylvania catchment: ecohydrologic patterns and processes

    Science.gov (United States)

    Brubaker, K. M.; Gaines, K.

    2015-12-01

    The connections between vegetation and catchment hydrology are important for tree physiology, plant geography, stream flow, and transport of solutes within a watershed. While water isotopes from tree stems have been studied extensively to examine source-water differences at a small scale, there has been little emphasis on modeling of plant stem water isotopes at larger scales, due to the expensive and laborious extraction and analysis processes. We characterized the tree stem water for stable isotopes over a landscape (isoscape) at a first-order catchment in central Pennsylvania in order to address the following questions: 1) How does tree water isotopic composition relate to catchment topography and tree characteristics? 2) What are the underlying hydrologic processes that are revealed by tree water isotopes? We used 267 observations of tree xylem water δ18O from 121 trees to build a statistical model with candidate variables related to topography and tree characteristics. We then applied the final model to predict the tree xylem water δ18O composition during the growing season of the remaining trees defined as > 18-cm diameter (at breast height; DBH) in the catchment. The final model included tree canopy height and slope magnitude as predictors, and explained about 56% of variance in tree water δ18O composition in the catchment. Tree canopy height and degree of slope were both negatively related to tree water δ18O suggesting the tallest trees and trees on the steepest slopes had tree water isotopic compositions most depleted in heavy isotopes. Each of these suggested the influence of cool-season isotopic inputs. On the valley floor, where tree canopy heights were tallest, the tree water δ18O composition was likely due to early growing season soil saturation from a shallow ground water table. Conversely, the steep hill slope δ18O composition may be a result of tree water use of tightly-bound soil water originating from cool season precipitation. The model

  20. Lack of differential pattern in central adiposity and metabolic syndrome in Barrett's esophagus and gastroesophageal reflux disease.

    LENUS (Irish Health Repository)

    Healy, L A

    2012-02-01

    Obesity is an established risk factor for esophageal adenocarcinoma, although the mechanism is unclear. A pathway from reflux to inflammation through metaplasia is the dominant hypothesis, and an added role relating to visceral adiposity and the metabolic syndrome has been mooted in Barrett\\'s esophagus (BE) patients. Whether BE differs from gastroesophageal reflux disease (GERD) in obesity and metabolic syndrome profiles is unclear, and this was the focus of this study. Patients with proven BE or GERD were randomly selected from the unit data registry and invited to attend for metabolic syndrome screening, anthropometry studies including segmental body composition analysis, and laboratory tests including fasting lipids, insulin, and C-reactive protein. Metabolic syndrome was defined using the National Cholesterol Education Program (NCEP) and the International Diabetes Federation (IDF) criteria. One hundred and eighteen BE patients and 113 age- and sex-matched GERD controls were studied. The incidence of obesity (body mass index >30 kg\\/m(2)) was 36% and 38%, respectively, with the pattern of fat deposition predominantly central and an estimated trunk fat mass of 13 and 14 kg, respectively. Using the NCEP criteria, metabolic syndrome was significantly more common in the BE cohort (30% vs 20%, P < 0.05), but there was no significant difference using IDF criteria (42% vs 37%, P= 0.340). Central obesity and the metabolic syndrome are common in both Barrett\\'s and GERD cohorts, but not significantly different, suggesting that central obesity and the metabolic syndrome does not per se impact on the development of BE in a reflux population. In BE, the importance of obesity and the metabolic syndrome in disease progression merits further study.

  1. Technological solutions of decentralized generation of hydroelectricity for those demands that cannot be attended by conventional electric with centralized generation

    Energy Technology Data Exchange (ETDEWEB)

    Signoretti, Valdir Tesche; Veras, Carlos Alberto Gurgel Rudi; Els, Henri Van [Universidade de Brasilia, Brasilia, DF (Brazil). Faculdade de Tecnologia. Dept. de Engenharia Mecanica], e-mail: gurgel@unb.br

    2010-07-01

    A source of energy stable and reliable and of acceptable cost is a basic requisite for the development of a given region can give-if full. Access to energy is important basis of human existence, essential to the satisfaction of basic needs such as food, clothing, and housing and also of mobility and communication. However, the dependency world burning of fossil fuels for energy generation and supply of a demand constantly increasing, both in industrialized countries and those in development, already threatening the ecological stability of the Earth. At the same time, conflicts by distribution of the last reserves these resources non-renewable threaten significantly to civil society. Adding to the breakneck speed in which humanity consumes the energetic sources and the obvious devastation of nature has an unequal distribution in consumption and access to energy. Renewable sources and energy efficiency are viable and necessary, especially because they can be the key to reduce wastefulness and extend the access to energy. In this way, there is a significant influence on economic and social inclusion of population excluded, generating employment and income with costs local and global environmental reduced compared to traditional forms and unsustainable generation and use of energy. This work is a study involving issues related to rural electrification from hydroelectricity, especially related to those isolated communities of the Amazon region that are lacking this form of energy, presented a general review since the origins of hydroelectricity in Brazil, as well as a national panorama electric exclusion as well as a scenario Amazon's supply of electricity. Finally presenting-if the main technologies available for hydroelectric generation for these isolated communities. (author)

  2. Nanophotonic reservoir computing with photonic crystal cavities to generate periodic patterns.

    Science.gov (United States)

    Fiers, Martin Andre Agnes; Van Vaerenbergh, Thomas; Wyffels, Francis; Verstraeten, David; Schrauwen, Benjamin; Dambre, Joni; Bienstman, Peter

    2014-02-01

    Reservoir computing (RC) is a technique in machine learning inspired by neural systems. RC has been used successfully to solve complex problems such as signal classification and signal generation. These systems are mainly implemented in software, and thereby they are limited in speed and power efficiency. Several optical and optoelectronic implementations have been demonstrated, in which the system has signals with an amplitude and phase. It is proven that these enrich the dynamics of the system, which is beneficial for the performance. In this paper, we introduce a novel optical architecture based on nanophotonic crystal cavities. This allows us to integrate many neurons on one chip, which, compared with other photonic solutions, closest resembles a classical neural network. Furthermore, the components are passive, which simplifies the design and reduces the power consumption. To assess the performance of this network, we train a photonic network to generate periodic patterns, using an alternative online learning rule called first-order reduced and corrected error. For this, we first train a classical hyperbolic tangent reservoir, but then we vary some of the properties to incorporate typical aspects of a photonics reservoir, such as the use of continuous-time versus discrete-time signals and the use of complex-valued versus real-valued signals. Then, the nanophotonic reservoir is simulated and we explore the role of relevant parameters such as the topology, the phases between the resonators, the number of nodes that are biased and the delay between the resonators. It is important that these parameters are chosen such that no strong self-oscillations occur. Finally, our results show that for a signal generation task a complex-valued, continuous-time nanophotonic reservoir outperforms a classical (i.e., discrete-time, real-valued) leaky hyperbolic tangent reservoir (normalized root-mean-square errors=0.030 versus NRMSE=0.127). PMID:24807033

  3. Radiometric profiles of uranium dispersal pattern adjacent to cretaceous phosphatic sediments in Wadi Qasser Al-Hallabat basin, central Syria

    International Nuclear Information System (INIS)

    A radiometric survey was carried out over clastic sediments in the immediate vicinity of some phosphatic sediments of Cretaceous age in the Wadi Qasser Al-Hallabat basin of central Syria. the objective was to explore for uranium and to define its dispersion pattern. This was based on ground radiometric surveys and geological studies. All ground surveys (using radon emanometry, track etching, gamma-ray survey and geochemistry) gave similar results outlining the locations of the radioactive phosphatic formations in the basin, and indicating the dispersion pattern of uranium in the clastic sediments in the surrounding area. The dispersal of uranium from upper Cretaceous phosphatic formation occurs by mechanical weathering and chemical leaching by oxidizing surface waters. A rough estimate is that about one-third of the original uranium content of the cretaceous sediments has been dispersed. Mechanical erosion is responsible for the main part of this released uranium, which now occurs in Recent sediments. However, the occurrences of spotty secondary U mineralization indicates that another small part of the available uranium must have been chemically leached out by the prevailing oxidizing waters, forming minor surficial minerals. (Author)

  4. Interannual variations in the hatching pattern, larval growth and otolith size of a sand-dwelling fish from central Chile

    Science.gov (United States)

    Rodríguez-Valentino, Camilo; Landaeta, Mauricio F.; Castillo-Hidalgo, Gissella; Bustos, Claudia A.; Plaza, Guido; Ojeda, F. Patricio

    2015-09-01

    The interannual variation (2010-2013) of larval abundance, growth and hatching patterns of the Chilean sand stargazer Sindoscopus australis (Pisces: Dactyloscopidae) was investigated through otolith microstructure analysis from samples collected nearshore (<500 m from shore) during austral late winter-early spring off El Quisco bay, central Chile. In the studied period, the abundance of larval stages in the plankton samples varied from 2.2 to 259.3 ind. 1000 m-3; larval abundance was similar between 2010 and 2011, and between 2012 and 2013, but increased significantly from 2011 to 2012. The estimated growth rates increased twice, from 0.09 to 0.21 mm day-1, between 2011 and 2013. Additionally, otolith size (radius, perimeter and area), related to body length of larvae, significantly decreased from 2010 to 2012, but increases significantly in 2013. Although the mean values of microincrement widths of sagitta otoliths were similar between 2010 and 2011 (around 0.6-0.7 μm), the interindividual variability increases in 2011 and 2013, suggesting large environmental variability experienced by larvae during these years. Finally, the hatching pattern of S. australis changed significantly from semi-lunar to lunar cycle after 2012.

  5. Concept and analytical basis for revistas - A fast, flexible computer/graphic system for generating periodic satellite coverage patterns

    Science.gov (United States)

    King, J. C.

    1976-01-01

    The generation of satellite coverage patterns is facilitated by three basic strategies: use of a simplified physical model, permitting rapid closed-form calculation; separation of earth rotation and nodal precession from initial geometric analyses; and use of symmetries to construct traces of indefinite length by repetitive transposition of basic one-quadrant elements. The complete coverage patterns generated consist of a basic nadir trace plus a number of associated off-nadir traces, one for each sensor swath edge to be delineated. Each trace is generated by transposing one or two of the basic quadrant elements into a circle on a nonrotating earth model sphere, after which the circle is expanded into the actual 'helical' pattern by adding rotational displacements to the longitude coordinates. The procedure adapts to the important periodic coverage cases by direct insertion of the characteristic integers N and R (days and orbital revolutions, respectively, per coverage period).

  6. Fractures Patterns of Tight Carbonates of Upper Jurassic Arab-D Member and Upper Jubaila Formation Outcrops, Central Saudi Arabia

    Science.gov (United States)

    Abdullatif, Osman; Abdlmutalib, Ammar

    2015-04-01

    This study investigates the fracture patterns of the upper Jurassic Arab-D member and upper Jubaila Formation outcropping in central Saudi Arabia. These strata represent the outcrop equivalent for Arab-D reservoir. The upper Jubaila Formation was deposited in the lower to upper slope to ramp crest leading to deposition Stromatoporoid lithofacies association, while Arab-D member deposited under deep to shallow lagoonal settings including skeletal bank and tidal flat lithofacies associations. This study utilized high resolution outcrop scale integrated fracture analysis, sedimentological and stratigraphical approach and methods.The field data included lithofacies, stratigraphic hierarchy, cyclicity and fracture measurements of orientation, length, spacing, intensity, and aperture. The Arab-D member is affected by five fracture patterns: (a) regular large scale fractures NW striking, several meters widely spaced, vertically dipping and cutting through several beds; (b) regular medium scale fractures striking NE and vertically dipping, moderately spaced and extending from two to three meters in length and cut through two or three beds; (c) regular small scale fractures that are arrested near the bed boundary vertically dipping and having less than one meter length and spacing; (d) irregular fractures filled with chemically weathered materials; (e) large scale fractures oriented perpendicular to the first fracture pattern in (a) along the outcrop strike and also cut on the top of the resistive sandy grainstone lithofacies of Arab D member. In contrast, the Upper Jubaila Formation is characterized mostly by medium scale NW and NE striking fractures that near vertically dipping and extended within one or two beds. Irregular small scale fractures also occur within parts of the beds of this group.Fracture formation and development in the Arab D and Jubaila Formation are partially attributed to regional tectonics affected the study area and locally to stratigraphic and

  7. Cost comparison of central electric power generation using coal and nuclear fuels

    International Nuclear Information System (INIS)

    This paper addresses the current and expected future costs of generating electricity with the two available practical modes of power generation, coal and nuclear. It describes the procedures and inputs used to arrive at the conclusion that generation with nuclear fuels will be about 16% more economical than generation with the best coal alternative. Recognizing the uncertainty in long range estimates of this type, various sensitivity checks are developed to determine how much the capital, fuel, and operating costs would have to change to force a change in the ranking of the alternatives. The results are current estimates of the costs of generating electricity in the future in the middle western area of the United States with large nuclear units, and with comparably sized and comparably loaded coal units firing high and low sulfur coals

  8. Characteristics of U-pattern distribution of high-concentration 210Pb in surface air at central Guizhou, China

    Institute of Scientific and Technical Information of China (English)

    WAN Guojiang; YANG Wei; WANG Shilu; WAN Enyuan; WU Fengchang; S.N.LEE; WANG Changsheng; HUANG Ronggui

    2005-01-01

    A better understanding of the variation of 210Pb concentrations in the surface air is the key to trace lake sedimentation and catchment erosion, to establish and validate the global diffusion model of contaminants, and to assess the impact of natural radiation on the ecological system. Basing on the study progresses of the sedimentation, the atmospheric model and the unique environmental background in the Yunnan-Guizhou Plateau, and starting from December 20, 2001, we made use of a 500 NE Type aerosol sampler to collect filter samples, once a week in the past consecutive two years, in the surface air at Mt. Guanfeng, Guiyang City, China. Synchronous detailed γ-energy spectrometric observations of 210Pb concentrations at both Chinese and U.S. laboratories have shown that the average monthly 210Pb concentration displays a regular U-patterns distribution of annual variations, with high values appearing in winter and low values in late spring and summer. The average annual 210Pb concentrations are estimated to be 2.77±0.63 mBq/m3, about 4 times the average maximum concentrations reported from quite a number of monitoring stations throughout the world. The possible factors affecting the sources of 210Pb in the surface air in the central part of Guizhou Province are: Release of 222Rn from the U-Ra series enriched in the soils; chemical weathering of carbonate rocks; the exploitation, processing and utilization of coal and phosphorous resources. The principal factor controlling the high 210Pb concentrations in the surface air in the central Guizhou and their annual U-pattern distribution is the release of 222Rn. The average monthly 210Pb concentrations show a good negative power- function relationship with increasing precipitation and also show a good negative linear-function relationship with the rise of air temperature in month grouping. Group No.1 (June to November) reflects a relatively low release of 222Rn from soils in relatively high temperature seasons; Group No

  9. Controlled positioning of nanobeads by strayfields of artificial topographically flat magnetic patterns generated by keV-He-ion bombardment

    International Nuclear Information System (INIS)

    Ion bombardment induced lateral magnetic patterning (IBMP) has been used to generate different magnetic patterns (artificial domains) in an IrMn/NiFe bilayer system without changes in the surface topography. This technique enables to create areas with effective antiparallel magnetizations in adjacent patterns stable in remanence. In the resulting stray fields (essentially emitted by the artificial domain walls) it is possible to position nanobeads along these walls. The dependence of this positioning on the domain wall width, domain wall type and size of the nanobeads is discussed, and first results are presented.

  10. Generation patterns of four groups of cholinergic neurons in rat cervical spinal cord: a combined tritiated thymidine autoradiographic and choline acetyltransferase immunocytochemical study

    International Nuclear Information System (INIS)

    This report examines the generation of cholinergic neurons in the spinal cord in order to determine whether the transmitter phenotype of neurons is associated with specific patterns of neurogenesis. Previous immunocytochemical studies identified four groups of choline acetyltransferase (ChAT)-positive neurons in the cervical enlargement of the rat spinal cord. These cell groups vary in both somatic size and location along the previously described ventrodorsal neurogenic gradient of the spinal cord. Thus, large (and small) motoneurons are located in the ventral horn, medium-sized partition cells are found in the intermediate gray matter, small central canal cluster cells are situated within lamina X, and small dorsal horn neurons are scattered predominantly through laminae III-V. The relationships among the birthdays of these four subsets of cholinergic neurons have been examined by combining 3H-thymidine autoradiography and ChAT immunocytochemistry. Embryonic day 11 was the earliest time that neurons were generated within the cervical enlargement. Large and small ChAT-positive motoneurons were produced on E11 and 12, with 70% of both groups being born on E11. ChAT-positive partition cells were produced between E11 and 13, with their peak generation occurring on E12. Approximately 70% of the cholinergic central canal cluster and dorsal horn cells were born on E13, and the remainder of each of these groups was generated on E14. Other investigators have shown that all neurons within the rat cervical spinal cord are produced in a ventrodorsal sequence between E11 and E16. In contrast, ChAT-positive neurons are born only from E11 to E14 and are among the earliest cells generated in the ventral, intermediate, and dorsal subdivisions of the spinal cord

  11. Risk and cost comparison of energy technologies for central electric power generation

    International Nuclear Information System (INIS)

    An evaluation of nuclear energy as it relates to alternative sources of electric power generation is presented. Citing Duke Power Company's Oconee Nuclear Station, the nuclear option in the past was the obvious choice. Today it is still the preferred alternative both economically and because of increasing environmental concerns over other energy alternatives. Public acceptance of nuclear generation, following Three Mile Island, remains a significant hurdle in its path

  12. Bayesian Spatiotemporal Pattern and Eco-climatological Drivers of Striped Skunk Rabies in the North Central Plains.

    Science.gov (United States)

    Raghavan, Ram K; Hanlon, Cathleen A; Goodin, Douglas G; Davis, Rolan; Moore, Michael; Moore, Susan; Anderson, Gary A

    2016-04-01

    Striped skunks are one of the most important terrestrial reservoirs of rabies virus in North America, and yet the prevalence of rabies among this host is only passively monitored and the disease among this host remains largely unmanaged. Oral vaccination campaigns have not efficiently targeted striped skunks, while periodic spillovers of striped skunk variant viruses to other animals, including some domestic animals, are routinely recorded. In this study we evaluated the spatial and spatio-temporal patterns of infection status among striped skunk cases submitted for rabies testing in the North Central Plains of US in a Bayesian hierarchical framework, and also evaluated potential eco-climatological drivers of such patterns. Two Bayesian hierarchical models were fitted to point-referenced striped skunk rabies cases [n = 656 (negative), and n = 310 (positive)] received at a leading rabies diagnostic facility between the years 2007-2013. The first model included only spatial and temporal terms and a second covariate model included additional covariates representing eco-climatic conditions within a 4km2 home-range area for striped skunks. The better performing covariate model indicated the presence of significant spatial and temporal trends in the dataset and identified higher amounts of land covered by low-intensity developed areas [Odds ratio (OR) = 3.41; 95% Bayesian Credible Intervals (CrI) = 2.08, 3.85], higher level of patch fragmentation (OR = 1.70; 95% CrI = 1.25, 2.89), and diurnal temperature range (OR = 0.54; 95% CrI = 0.27, 0.91) to be important drivers of striped skunk rabies incidence in the study area. Model validation statistics indicated satisfactory performance for both models; however, the covariate model fared better. The findings of this study are important in the context of rabies management among striped skunks in North America, and the relevance of physical and climatological factors as risk factors for skunk to human rabies transmission and the

  13. Bayesian Spatiotemporal Pattern and Eco-climatological Drivers of Striped Skunk Rabies in the North Central Plains

    Science.gov (United States)

    Raghavan, Ram K.; Hanlon, Cathleen A.; Goodin, Douglas G.; Anderson, Gary A.

    2016-01-01

    Striped skunks are one of the most important terrestrial reservoirs of rabies virus in North America, and yet the prevalence of rabies among this host is only passively monitored and the disease among this host remains largely unmanaged. Oral vaccination campaigns have not efficiently targeted striped skunks, while periodic spillovers of striped skunk variant viruses to other animals, including some domestic animals, are routinely recorded. In this study we evaluated the spatial and spatio-temporal patterns of infection status among striped skunk cases submitted for rabies testing in the North Central Plains of US in a Bayesian hierarchical framework, and also evaluated potential eco-climatological drivers of such patterns. Two Bayesian hierarchical models were fitted to point-referenced striped skunk rabies cases [n = 656 (negative), and n = 310 (positive)] received at a leading rabies diagnostic facility between the years 2007–2013. The first model included only spatial and temporal terms and a second covariate model included additional covariates representing eco-climatic conditions within a 4km2 home-range area for striped skunks. The better performing covariate model indicated the presence of significant spatial and temporal trends in the dataset and identified higher amounts of land covered by low-intensity developed areas [Odds ratio (OR) = 3.41; 95% Bayesian Credible Intervals (CrI) = 2.08, 3.85], higher level of patch fragmentation (OR = 1.70; 95% CrI = 1.25, 2.89), and diurnal temperature range (OR = 0.54; 95% CrI = 0.27, 0.91) to be important drivers of striped skunk rabies incidence in the study area. Model validation statistics indicated satisfactory performance for both models; however, the covariate model fared better. The findings of this study are important in the context of rabies management among striped skunks in North America, and the relevance of physical and climatological factors as risk factors for skunk to human rabies transmission and

  14. Patterns of mouse reticulon 3 mRNA and protein expression in the mouse central nervous system

    Institute of Scientific and Technical Information of China (English)

    LIU Jin; QIANG Boqin; YUAN Jiangang; HUANG Xiaowei; PENG Xiaozhong; YANG Hongbo; YIN Bin; TAN Xinyu; FAN Ming; FAN Wenhong; LIU Bingyan

    2003-01-01

    Reticulons (RTN) are endoplasmic reticulumassociated protein complexes, which are localized in the endoplasmic reticulum (ER) and identified as markers for neuroendocrine differentiation. At least four different RTN genes have been identified in mammals, but in most cases,the functions of the encoded proteins except mammalian RTN4-A and RTN4-B are still elusive. In the present study,mouse reticulon 3 (mRTN3) is cloned and its expression pattern in a variety of tissues is investigated. Three alternatively spliced transcripts of 1.8, 2.8 and 4.2 kb are revealed by Northern blotting hybridization. The 1.8 and 2.8 kb transcripts are expressed in many tissues. The 2.8 kb transcript has a high level in brain and the 4.2 kb transcript is only found in brain. In situ hybridization and immunohistochemical analysis indicated its high expression in non-glial cells in some particular region of mouse central nervous system, such as hippocampus, sub-thalamus nucleus, thalamus nucleus and cerebrum cortex.

  15. Spatial pattern analysis of landslide using landscape metrics and logistic regression: a case study in Central Taiwan

    Directory of Open Access Journals (Sweden)

    Y.-P. Lin

    2010-06-01

    Full Text Available The Chi-Chi Earthquake of September 1999 in Central Taiwan registered a moment magnitude MW of 7.6 on the Richter scale, causing widespread landslides. Subsequent typhoons associated with heavy rainfalls triggered the landslides. The study investigates multi-temporal landslide images from spatial analysis between 1996 and 2005 in the Chenyulan Watershed, Taiwan. Spatial patterns in various landslide frequencies were detected using landscapes metrics. The logistic regression results indicate that frequency of occurrence is an important factor in assessing landslide hazards. Low-occurrence landslides sprawl the catchment while the sustained (frequent landslide areas cluster near the ridge as well as the stream course. From those results, we can infer that landslide area and mean size for each landslide correlates with the frequency of occurrence. Although negatively correlated with frequency in the low-occurrence landslide, the mean size of each landslide is positively related to frequency in the high-occurrence one. Moreover, this study determines the spatial susceptibilities in landslides by performing logistic regression analysis. Results of this study demonstrate that the factors such as elevation, slope, lithology, and vegetation cover are significant explanatory variables. In addition to the various frequencies, the relationships between driving factors and landslide susceptibility in the study area are quantified as well.

  16. Patterns of fossil distributions within their environmental context from the Middle Triassic in South Canyon,Central Nevada,USA

    Institute of Scientific and Technical Information of China (English)

    Pedro; M.Monarrez; Nicole; Bonuso

    2014-01-01

    The Middle Triassic records the return of diverse marine communities after the severe effects of the end-Permian mass extinction.This diversification leads to the Mesozoic/modern adaptive radiation resulting in substantial changes in marine communities in comparison to their Paleozoic predecessors.This analysis focuses on the faunal abundance,ecological patterns,and environmental interpretation of a Middle Triassic section in Central Nevada.Twelve bulk samples were collected.Visible fossils were identified and tallied from hand samples and thin-sections were used to aid in environmental interpretation.Beginning in the Late Anisian,we observed an ammonoid dominated to flat-clam,epifaunal dominated benthic community within a muddy,quiet,inner shelf depositional environment.Through time,epifaunal bivalves dominate within a middle shelf environment followed by an increase in infaunalization and shell-thickness.During this time the presence of oncoids and the reported finding of corals suggest the middle shelf environment gave way to a higher energy patch reef shelf edge environment.Finally,we observe epifaunal brachiopods communities at the top of our section deposited in a middle shelf environment.In sum,we observe the dominance of modern taxa(i.e.,bivalves)with Paleozoic ecologies(i.e.,epifaunal),followed by the dominance of modern taxa with Modern ecologies(i.e.,infaunal,thick shells)and then a return to Paleozoic taxa(i.e.,brachiopods)and Paleozoic ecologies within an overall transgressive environment.

  17. Determining the impact of wind on system costs via the temporal patterns of load and wind generation

    International Nuclear Information System (INIS)

    Ambitious targets have been set for expanding electricity generation from renewable sources, including wind. Expanding wind power impacts needs for other electricity generating resources. As states plan for increasing levels of wind generation in their portfolio of generation resources it is important to consider how this intermittent resource impacts the need for other generation resources. A case study for Indiana estimates the value of wind capacity and demonstrates how to optimize its level and the levels of other generation resources. Changes are driven by temporal patterns of wind power output and load. System wide impacts are calculated for energy, capacity, and costs under multiple wind expansion scenarios which highlight the geographic characteristics of a systems portfolio of wind generation. The impacts of carbon prices, as proposed in the Bingaman Bill, are considered. Finally, calculations showing the effect increasing levels of wind generation will have on end use Indiana retail rates are included. - Highlights: • We estimate the value of wind capacity. • We determine wind generation's impact on the optimal mix of non-wind generation. • Optimal levels of wind and non-wind generation are determined. • We consider the impact of a carbon price on the optimal mix of resources. • The impact of additional wind capacity on Indiana residential rates is calculated

  18. Designing responsive pattern generators: stable heteroclinic channel cycles for modeling and control.

    Science.gov (United States)

    Horchler, Andrew D; Daltorio, Kathryn A; Chiel, Hillel J; Quinn, Roger D

    2015-04-01

    A striking feature of biological pattern generators is their ability to respond immediately to multisensory perturbations by modulating the dwell time at a particular phase of oscillation, which can vary force output, range of motion, or other characteristics of a physical system. Stable heteroclinic channels (SHCs) are a dynamical architecture that can provide such responsiveness to artificial devices such as robots. SHCs are composed of sequences of saddle equilibrium points, which yields exquisite sensitivity. The strength of the vector fields in the neighborhood of these equilibria determines the responsiveness to perturbations and how long trajectories dwell in the vicinity of a saddle. For SHC cycles, the addition of stochastic noise results in oscillation with a regular mean period. In this paper, we parameterize noise-driven Lotka-Volterra SHC cycles such that each saddle can be independently designed to have a desired mean sub-period. The first step in the design process is an analytic approximation, which results in mean sub-periods that are within 2% of the specified sub-period for a typical parameter set. Further, after measuring the resultant sub-periods over sufficient numbers of cycles, the magnitude of the noise can be adjusted to control the mean period with accuracy close to that of the integration step size. With these relationships, SHCs can be more easily employed in engineering and modeling applications. For applications that require smooth state transitions, this parameterization permits each state's distribution of periods to be independently specified. Moreover, for modeling context-dependent behaviors, continuously varying inputs in each state dimension can rapidly precipitate transitions to alter frequency and phase. PMID:25712192

  19. Trading Signal Generation Using A Combination of Chart Patterns and Indicators

    OpenAIRE

    Chalothon Chootong; Ohm Sornil,

    2012-01-01

    Chart patterns and indicators are popular technical tools for making investment decisions. This article presents a trading strategy combining price movement patterns, candlestick chart patterns, and trading indicators, including Moving Average, Exponential Moving Average, Bollinger Bands, On Balance Volume, Relative Strength Index, Moving Average Convergence Divergence, and Stochastic Oscillator, with the aim to increase the return on investment. A neural network ensemble is employed to deter...

  20. Development of the control assembly pattern and dynamic analysis of the Generation IV large gas-cooled fast reactor (GFR)

    International Nuclear Information System (INIS)

    During the past ten years, different independent factors, such as the rapidly increasing worldwide demand in energy, societal concerns about greenhouse gas emissions, and the high and volatile prices for fossil fuels, have contributed to the renewed interest in nuclear technology. In this context, the Generation IV International Forum (GIF) launched the initiative to collaborate on the research and development efforts needed for the next generation of nuclear reactors. A particular goal set for Generation IV systems is closure of the nuclear fuel cycle; they are expected to offer a better utilization of natural resources, as also a minimization of long-lived radioactive wastes. Among the systems selected by the GIF, the Gas-cooled Fast Reactor (GFR) is a highly innovative system with advanced fuel geometry and materials. The principal aim of the present research is to develop and qualify the control assembly (CA) pattern and corresponding CA implementation scheme for the 2400 MWth reference GFR design. The work has been carried out in three successive phases: (1) validation of the neutronics tools, (2) the CA pattern development and related static analysis, and (3) dynamic core behaviour studies for hypothetical CA driven transients. The deterministic code system ERANOS and its associated nuclear data libraries for fast reactors were developed and validated for sodium-cooled reactors. In order to validate ERANOS for GFR applications, a systematic reanalysis of the GFR-relevant integral data generated at PSI during the GCFR-PROTEUS experimental program of the 1970’s was undertaken. The reference PROTEUS test lattice has been analyzed with ERANOS-2.0 and its associated, adjusted nuclear data library ERALIB1. Benchmark calculations were performed with the Monte Carlo code MCNPX, allowing one to both check the deterministic results and to analyze the sensitivity to different modern data libraries. For the main reaction rate ratios, the new analysis of the GCFR

  1. Sustainability Assessment of a Self-Consumption Wood-Energy Chain on Small Scale for Heat Generation in Central Italy

    OpenAIRE

    Stefano Verani; Giulio Sperandio; Rodolfo Picchio; Enrico Marchi; Corrado Costa

    2015-01-01

    The sustainability of a small-scale self-consumption wood-energy chain for heat generation in central Italy was analyzed from a technical, economic and energetic point of view. A micro-chain was developed within the CRA-ING farm at Monterotondo (Rome, Italy): The purpose of this system was to produce biomass for supplying a heating plant within the CRA-ING property as a substitute for diesel fuel. A poplar short rotation coppice, established with clones AF2, AF6 and Monviso, fed the micro-cha...

  2. Evaluating the temporal stability of synthetically generated time-series for crop types in central Germany

    Science.gov (United States)

    Synthetically generated Landsat time-series based on the STARFM algorithm are increasingly used for applications in forestry or agriculture. Although successes in classification and derivation of phenological orbiomass parameters are evident, a thorough evaluation of the limits of the method is stil...

  3. CENCAL_BASELINE - Offshore Baseline for Central California Generated to Calculate Shoreline Change Rates

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Rates of long-term and short-term shoreline change were generated in a GIS using the Digital Shoreline Analysis System (DSAS) version 3.0; An ArcGIS extension for...

  4. Wave of chaos in a diffusive system: Generating realistic patterns of patchiness in plankton-fish dynamics

    International Nuclear Information System (INIS)

    We show that wave of chaos (WOC) can generate two-dimensional time-independent spatial patterns which can be a potential candidate for understanding planktonic patchiness observed in marine environments. These spatio-temporal patterns were obtained in computer simulations of a minimal model of phytoplankton-zooplankton dynamics driven by forces of diffusion. We also attempt to figure out the average lifetimes of these non-linear non-equilibrium patterns. These spatial patterns serve as a realistic model for patchiness found in aquatic systems (e.g., marine and oceanic). Additionally, spatio-temporal chaos produced by bi-directional WOCs is robust to changes in key parameters of the system; e.g., intra-specific competition among individuals of phytoplankton and the rate of fish predation. The ideas contained in the present paper may find applications in diverse fields of human endeavor.

  5. Primary seed shadow generated by gibbons in the rain forests of Barito Ulu, central Borneo.

    Science.gov (United States)

    McConkey, K R

    2000-09-01

    Gibbons are one of the main frugivores in the forests of Southeast Asia, and consequently have long been considered to be good seed dispersers. This is the first study in which the primary seed shadow they create by their ranging and foraging activities is evaluated in detail. I studied two gibbon groups over 12 months in lowland dipterocarp forest in central Borneo. The gibbons dispersed up to 81% of the species they consumed and destroyed the seeds of only 12%. Fruit with elongated seeds (up to 20 mm wide) were more likely to be dispersed than round seeds. Considering that the survival rate of seeds in the forest to one year was 8%, the gibbons effectively dispersed 13 seedlings ha(-1) group(-1) year(-1). Their effect on germination was very variable, although most species did eventually germinate. Most seeds were deposited along their major ranging routes and close to or under feeding trees. PMID:10993135

  6. Centralized optical-frequency-comb-based RF carrier generator for DWDM fiber-wireless access systems

    DEFF Research Database (Denmark)

    Pang, Xiaodan; Beltran, Marta; Sanchez, Jose;

    2014-01-01

    In this paper, we report on a gigabit capacity fiber-wireless system that enables smooth integration between high-speed wireless networks and dense wavelength-division-multiplexing (DWDM) access networks. By employing a centralized optical frequency comb, both the wireline and the wireless services...... applications. For demonstration, we transmit a 2.5 Gbit/s signal through the proposed system and successfully achieve a bit-error-rate (BER) performance well below the 7% overhead forward error correction limit of the BER of 2 × 10¿3 for both the wireline and the wireless signals in the 60 GHz band after 25 km...... single-mode fiber plus up to 6 m wireless distance....

  7. Performance analysis of a Kalina cycle for a central receiver solar thermal power plant with direct steam generation

    DEFF Research Database (Denmark)

    Modi, Anish; Haglind, Fredrik

    2014-01-01

    Solar thermal power plants have attracted increasing interest in the past few years - with respect to both the design of the various plant components, and extending the operation hours by employing different types of storage systems. One approach to improve the overall plant efficiency is to use...... without corroding the equipment by using suitable additives with the mixture. The purpose of the study reported here was to investigate if there is any benefit of using a Kalina cycle for a direct steam generation, central receiver solar thermal power plant with high live steam temperature (450 C...... direct steam generation with water/steam as both the heat transfer fluid in the solar receivers and the cycle working fluid. This enables operating the plant with higher turbine inlet temperatures. Available literature suggests that it is feasible to use ammonia-water mixtures at high temperatures...

  8. Extreme ultraviolet lithography patterned mask defect detection performance evaluation toward 16- to 11-nm half-pitch generation

    Science.gov (United States)

    Hirano, Ryoichi; Iida, Susumu; Amano, Tsuyoshi; Watanabe, Hidehiro; Hatakeyama, Masahiro; Murakami, Takeshi; Yoshikawa, Shoji; Terao, Kenji

    2015-07-01

    High-sensitivity and low-noise extreme ultraviolet (EUV) mask pattern defect detection is one of the major issues remaining to be addressed in device fabrication using extreme ultraviolet lithography (EUVL). We have designed a projection electron microscopy (PEM) system, which has proven to be quite promising for half-pitch (hp) 16-nm node to hp 11-nm node mask inspection. The PEM system was integrated into a pattern inspection system for defect detection sensitivity evaluation. To improve the performance of hp 16-nm patterned mask defect detection toward hp 11-nm EUVL patterned mask, defect detection signal characteristics, which depend on hp 64-nm pattern image intensity deviation on EUVL mask, were studied. Image adjustment effect of the captured images for die-to-die defect detection was evaluated before the start of the defect detection image-processing sequence. Image correction of intrafield intensity unevenness and L/S pattern image contrast deviation suppresses the generation of false defects. Captured images of extrusion and intrusion defects in hp 64-nm L/S patterns were used for detection. Applying the image correction for defect detection, 12-nm sized intrusion defect, which was smaller than our target size for hp 16-nm defect detection requirements, was identified without false defects.

  9. Entamoeba histolytica cell movement: A central role for self-generated chemokines and chemorepellents

    OpenAIRE

    Zaki, Mehreen; Andrew, Natalie; Insall, Robert H.

    2006-01-01

    Entamoeba histolytica cells, the cause of amoebic dysentery, are highly motile, and this motility is an essential feature of the pathogenesis and morbidity of amoebiasis. However, the control of E. histolytica motility within the gut and during invasion is poorly understood. We have used an improved chemotaxis assay to identify the key extracellular signals mediating Entamoeba chemotaxis. The dominant responses we observe are caused by factors generated by E. histolytica cells themselves. Med...

  10. Determination of activity by gamma spectrometry of radionuclides present in drums of residues generated in nuclear centrals; Determinacion de actividad por espectrometria gamma de radionucleidos presentes en tambores de residuos generados en centrales nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Aguiar, J.C.; Fernandez, J. [Autoridad Regulatoria Nuclear, Av. Del Libertador 8250, Ciudad Autonoma de Buenos Aires (Argentina)]. e-mail: jaguiar@cae.arn.gov.ar

    2006-07-01

    The generation of radioactive residuals in nuclear centrals as CNA I (Atucha I Nuclear Central) and CNE (Embalse Nuclear Central) makes that the measurement of those radionuclides has been a previous stage to the waste management. A method used in those nuclear centrals it is the gamma spectrometry with HPGe detectors, previous to the immobilization of the residual in a cemented matrix, with this the contact with the external agents and its possible dispersion to the atmosphere in the short term is avoided. The ARN (Nuclear Regulatory Authority) of Argentina it carries out periodically intercomparisons and evaluations of the measurement and procedures systems used in the nuclear power stations for the correct measurement and determination of activity of radioactive residuals by gamma spectrometry. In this work an independent method of measurement is exposed to the nuclear power stations. To determine the activity of the residuals by gamma spectrometry deposited in drums, it is required of the precise knowledge of the efficiency curve for such geometry and matrix. Due to the RNA doesn't have a pattern of these characteristics, a mathematical model has been used to obtain this efficiency curve. For it, it is necessary to determine previously: 1) the geometric efficiency or solid angle sustained by the source-detector system (drum-detector) applying a mathematical model described in this work. 2) To estimate the auto-attenuation factor that present the photons in the cemented matrix, these calculations are carried out with a simple equation and its are verified with the Micro Shield 6.10 program. The container commonly used by these nuclear power stations its are drums for 220 liters constructed with SAE 1010 steel and with a thickness of 0.127 cm, with an approximate weight 7.73 Kg., internal diameter of 57.1 cm, and height: 87 cm. The results obtained until the moment register a discrepancy from 5 to 10% with relationship to the measurements carried out by the

  11. Choice between hierarchy and market: Case of Central Electricity Generating Board's reorganization

    International Nuclear Information System (INIS)

    Through the use of the 'Organization and Market' theoretical approach, this article outlines CEGB's reorganization to evaluate this experience under the strategic planning and operating effectiveness perspectives. The first part synthesizes the basic points of the 1990 reform which divided CEGB into three different companies and separated the control of the generation of electric power from its transport. The second part summarizes the main considerations about conditions of efficiency of vertical integration and disintegration, according to the 'Organization and Market' approach. By utilizing the conclusions highlighted in the first two parts of this article, the third one studies the effects of CEGB's vertical disintegration on the level of competition in power generation market; on CEGB's strategic effectiveness and operative efficiency; and on transactional costs in the electric power industry. CEGB's reorganization does not seem to have had a relevantly positive effect on competition, while it has caused a strategic burden and a significant increase of transactional costs in the exchange of electricity between the generator and the transmitter

  12. Patterns of distribution and abundance of the stalked barnacle (Pollicipes pollicipes) in the central and southwest coast of continental Portugal

    Science.gov (United States)

    Sousa, Alina; Jacinto, David; Penteado, Nélia; Martins, Pedro; Fernandes, Joana; Silva, Teresa; Castro, João J.; Cruz, Teresa

    2013-10-01

    The stalked barnacle Pollicipes pollicipes is a cirriped crustacean that lives on very exposed rocky shores. This barnacle is the most important economical resource on intertidal rocky shores of continental Portugal. It is highly prized as food and heavily exploited (professional and recreational fishery), but fishery data are scarce and do not estimate the real pressure upon this resource. Despite its socio-economic interest, specific regulations on this fishery are recent and different along the Portuguese coast. Four regions with different regulation can be identified: the marine reserve “Reserva Natural das Berlengas” (RNB) and the marine park “Parque Marinho Prof. Luiz Saldanha” (PMLS) (both in central Portugal); the natural park located in SW Portugal (“Parque Natural do Sudoeste Alentejano e Costa Vicentina”, PNSACV); and the rest of the coast. The main objective of the present study was to study the spatial patterns of percentage cover, biomass, density and size structure of P. pollicipes in areas with different exploitation regimes, including harvested areas and no-take areas. Additionally, variability between mid shore and low shore barnacles was also analysed. Seven areas were sampled with a variable number of sites (a total of 24) randomly sampled in each area during 2011. Photographs and image analysis (percentage cover) and destructive sampling (density, biomass and size) were used. In general, percentage cover, biomass and density were higher in mid shore when compared to low shore, namely in harvested areas. Low shore barnacles had a higher proportion of adults with moderate and high commercial value, while juveniles were relatively more abundant at mid shore. There were no consistent differences in the patterns of distribution and abundance of P. pollicipes among areas subject to different exploitation regimes. The most different area was the harvested area by professional fishers in RNB, where the highest biomass within the study was

  13. Convective thermal fluxes in unsteady non-homogeneous flows generating complex three dimensional vorticity patterns

    Science.gov (United States)

    Tellez Alvarez, Jackson David; Redondo, Jose Manuel; Sanchez, Jesu Mary

    2016-04-01

    The improvements in experimental methods and high resolution image analysis are nowadays able to detect subtle changes in the structure of the turbulence over a wide range of temporal and spatial scales [1], we compare the scaling shown by different mixing fronts driven by buoyancy that form convective driven mixing. We use PIV and density front tracking in several experimental configurations akin to geophysical overturning [2, 3]. We parametrize the role of unstable stratification by means of the Rayleigh and Atwood numbers and compare the scaling and the multifractal structure functions of the different markers used to visualize the non-homogeneous. Both reactive and passive scalar tracers are used to investigate the mixing structure and the intermittency of the flow. Different initial conditions are compared and the mixing efficiency of the overall turbulent process is evaluated [4 - 6]. Diffusion is measured in the transition from a homogeneous linearly stratified fluid to a cellular or layered structure by means of Thermoelectric generated heating and cooling [2, 4]. Patterns arise by setting up a convective flow generated by a buoyant heat flux either in the base or in a side wall of the convective enclosure [1, 6]. The experiments described here investigate high Prandtl number mixing using brine or sugar solutions and fresh water in order to form a density interface and low Prandtl number mixing with only temperature gradients [7]. The set of dimensionless parameters define conditions of numeric and small scale laboratory modeling of environmental flows. Fields of velocity, density and their gradients were computed and visualized [8, 9]. When convective heating and cooling takes place the combination of internal waves and buoyant turbulence is much more complicated if the Rayleigh and Reynolds numbers are high in order to study entrainment and mixing. The experiments described here investigate high Prandtl number mixing using salt or sugar solutions and

  14. Gravitational Wave (GW) Radiation Pattern at the Focus of a High-Frequency GW (HFGW) Generator and Aerospace Applications

    Science.gov (United States)

    Baker, Robert M. L.; Davis, Eric W.; Woods, R. C.

    2005-02-01

    The Gravitational Wave (GW) radiation pattern is derived that results from a rod rotating about a pivot, a dumbbell rotating about its central axis, a pair of stars rotating about their orbital focus, or a stationary circular asymmetrical-array of tangentially jerking elements. The three-dimensional shape of the GW radiation pattern is like a dumbbell cross-section having its long axis perpendicular to the plane of motion or along the central axis of the stationary ring of sequentially jerking elements. The center of the radiation pattern is situated at the pivot, orbital-focus, or center of the stationary array. Knowledge of the GW radiation pattern allows for optimum placement of a detector. In the case of High-Frequency Gravitational Waves (HFGWs), in which the diffraction of the GW radiation is less than the dimensions of the ring of jerking elements, the radiation pattern is situated at the center of the ring and represents a focus or concentration point of the HFGWs, The concentration point extends over a diffraction-limited spot having a radius of λGW/π, where λGW is the wavelength of the HFGW. In the case of a superconductor, prior research, although speculative has shown that the GW wavelength is foreshortened by a factor of about 300. Thus there could be a much more concentrated diffraction-limited flux of HFGW at the focus. It is shown that the efficiency of a HFGW communications link could be approximately proportional to the sixth power of the HFGW frequency. Applications to space technology, involving aerospace communications, and Astronomy are discussed.

  15. [Isoforms of the human histamine H3 receptor: Generation, expression in the central nervous system and functional implications].

    Science.gov (United States)

    García-Gálvez, Ana Maricela; Arias-Montaño, José Antonio

    2016-01-01

    Histamine plays a significant role as a neuromodulator in the human central nervous system. Histamine-releasing neurons are exclusively located in the tuberomammillary nucleus of the hypothalamus, project to all major areas of the brain, and participate in functions such as the regulation of sleep/wakefulness, locomotor activity, feeding and drinking, analgesia, learning, and memory. The functional effects of histamine are exerted through the activation of four G protein-coupled receptors (H1, H2, H3 and H4), and in the central nervous system the first three receptors are widely expressed. The H3 receptor (H3R) is found exclusively in neuronal cells, where it functions as auto- and hetero-receptor. One remarkable characteristic of the H3R is the existence of isoforms, generated by alternative splicing of the messenger RNA. For the human H3R, 20 isoforms have been reported; although a significant number lack those regions required for agonist binding or receptor signaling, at least five isoforms appear functional upon heterologous expression. In this work we review the evidence for the generation of human H3R isoforms, their expression, and the available information regarding the functionality of such receptors. PMID:26927649

  16. Trading Signal Generation Using A Combination of Chart Patterns and Indicators

    Directory of Open Access Journals (Sweden)

    Chalothon Chootong

    2012-11-01

    Full Text Available Chart patterns and indicators are popular technical tools for making investment decisions. This article presents a trading strategy combining price movement patterns, candlestick chart patterns, and trading indicators, including Moving Average, Exponential Moving Average, Bollinger Bands, On Balance Volume, Relative Strength Index, Moving Average Convergence Divergence, and Stochastic Oscillator, with the aim to increase the return on investment. A neural network ensemble is employed to determine buy and sell signals on the next trading day. Experimental results, using stocks from five different industries in Stock Exchange of Thailand, show that the proposed strategy yields higher returns than do traditional technical trading methods

  17. Gauge field theory of horizontal symmetry generated by a central extension of the pauli algebra

    International Nuclear Information System (INIS)

    The standard model of particle physics is generalized so as to be furnished with a horizontal symmetry generated by an intermediate algebra between simple Lie algebras su(2) and su(3). Above a certain high-energy scale Λ, the horizontal gauge symmetry is postulated to hold so that the basic fermions, i.e., quarks and leptons, form its fundamental triplets, and a triplet and singlet of the horizontal gauge fields distinguish generational degrees of freedom. A horizontal scalar triplet is introduced to make the gauge fields supermassive by breaking the horizontal symmetry at Λ. From this scalar triplet, real scalar fields emerge that do not interact with fermions except for neutrino species and may have a substantial influence on the evolution of the universe. Another horizontal scalar triplet that breaks the electroweak symmetry at a low-energy scale Λ≅2 x 102 GeV reproduces all of the results of the Weinberg-Salam theory, produces hierarchical mass matrices with fewer unknown parameters in a unified way and predicts six massive scalar particles, some of which might be observed in future LHC experiments. (author)

  18. Comparison between patterns generated by microcontact printing and dip-pen nanolithography on

    OpenAIRE

    Wampler, Heeyeon P.; Zemlyanov, Dmitry; Ivanisevic, Albena

    2007-01-01

    InP surfaces were patterned by microcontact printing and dip-pen nanolithography (DPN). The chemical nature and coverage of the functionalized surfaces were evaluated by X-ray photoelectron spectroscopy. The presence of all adsorbates on the surface was verified. The XPS data confirmed the covalent attachment of the adsorbates when microcontact printing was used, but no evidence for covalent bonding was observed when InP was patterned by DPN.

  19. A New Generation of Large Seismic Refraction Experiments in Central Europe (1997-2003)

    Science.gov (United States)

    Guterch, A.; Grad, M.; Spicak, A.; Brueckl, E.; Hegedus, E.; Keller, G. R.; Thybo, H.

    2003-12-01

    Beginning in 1997, Central Europe has been covered by an unprecedented network of seismic refraction experiments. These experiments (POLONAISE'97, CELEBRATION 2000, ALP 2002, SUDETES 2003) have only been possible due a massive international cooperative effort. The total length of all profiles is about 19,000 km, and over 300 explosive sources were employed. The result is a network of seismic refraction profiles that extends along the Trans-European Suture Zone region of Poland and the Bohemian massif, Pannonian basin, trough the Carpathians and Alps to the Adriatic Sea and the Dinarides. As reflected in structures within these areas, Central Europe has experienced a complex tectonic history that includes the Caledonian, Variscan, and Alpine orogenies. The related TESZ region is a broad zone of deformation that extends across Europe from British Isles to the Black Sea region that formed as Europe was assembled from a complex collage of terranes during the late Palaeozoic. For example, the Bohemian massif is mostly located in the Czech Republic and is a large, complex terrane whose origin can be traced to northern Gondwana (Africa). These terranes were accreted along the margin of Baltica that was formed during the break-up of Rodinia. The tectonic evolution of this region shares many attributes with the Appalachian/Ouachita origin and is certainly of global important to studies in terrane tectonics and continental evolution. In southern Poland, several structural blocks are located adjacent to Baltica and were probably transported laterally along it similar to the Cenozoic movement of terranes along the western margin of North America. The younger Carpathian arc and Pannonian back-arc basin were also targeted by these experiments. Thickness of the crust in the area of investigations changes from 22-25 km in the Pannonian basin to about 55 km in the Trans-European Suture Zone in SE Poland. Together, these experiments are providing an unprecedented 3-D image of the

  20. Convective thermal fluxes in unsteady non-homogeneous flows generating complex three dimensional vorticity patterns

    Science.gov (United States)

    Tellez Alvarez, Jackson David; Redondo, Jose Manuel; Sanchez, Jesu Mary

    2016-04-01

    The improvements in experimental methods and high resolution image analysis are nowadays able to detect subtle changes in the structure of the turbulence over a wide range of temporal and spatial scales [1], we compare the scaling shown by different mixing fronts driven by buoyancy that form convective driven mixing. We use PIV and density front tracking in several experimental configurations akin to geophysical overturning [2, 3]. We parametrize the role of unstable stratification by means of the Rayleigh and Atwood numbers and compare the scaling and the multifractal structure functions of the different markers used to visualize the non-homogeneous. Both reactive and passive scalar tracers are used to investigate the mixing structure and the intermittency of the flow. Different initial conditions are compared and the mixing efficiency of the overall turbulent process is evaluated [4 - 6]. Diffusion is measured in the transition from a homogeneous linearly stratified fluid to a cellular or layered structure by means of Thermoelectric generated heating and cooling [2, 4]. Patterns arise by setting up a convective flow generated by a buoyant heat flux either in the base or in a side wall of the convective enclosure [1, 6]. The experiments described here investigate high Prandtl number mixing using brine or sugar solutions and fresh water in order to form a density interface and low Prandtl number mixing with only temperature gradients [7]. The set of dimensionless parameters define conditions of numeric and small scale laboratory modeling of environmental flows. Fields of velocity, density and their gradients were computed and visualized [8, 9]. When convective heating and cooling takes place the combination of internal waves and buoyant turbulence is much more complicated if the Rayleigh and Reynolds numbers are high in order to study entrainment and mixing. The experiments described here investigate high Prandtl number mixing using salt or sugar solutions and

  1. Generating Frequent Patterns from Large Datasets using Improved Apriori and Support Chaining Method

    OpenAIRE

    P. Alagesh Kannan; E. Ramaraj

    2015-01-01

    In this study, generating association rules with improved Apriori algorithm is proposed. Apriori is one of the most popular association rule mining algorithm that extracts frequent item sets from large databases. The traditional Apriori algorithm contains a major drawback. This algorithm wastes time in scanning the database to generate frequent item sets. The objective of any association rule mining algorithm is to generate association rules in a fast manner with great accuracy. In this study...

  2. Assessment of the once-through cooling alternative for central steam-electric generating stations

    International Nuclear Information System (INIS)

    The efficacy of the disposal of waste heat from steam-electric power generation by means of once-through cooling systems was examined in the context of the physical aspects of water quality standards and guidelines for thermal discharges. Typical thermal standards for each of the four classes of water bodies (rivers, lakes, estuaries, and coastal waters) were identified. The mixing and dilution characteristics of various discharge modes ranging from simple, shoreline surface discharges to long, submerged multiport diffusers were examined in terms of the results of prototype measurements, analytical model predictions, and physical model studies. General guidelines were produced that indicate, for a given plant capacity, a given type of receiving water body, and a given discharge mode, the likelihood that once-through cooling can be effected within the restrictions of typical thermal standards. In general, it was found that shoreline surface discharges would not be adequate for large power plants (greater than or equal to 500 MW) at estuarine and marine coastal sites, would be marginally adequate at lake sites, and would be acceptable only at river sites with large currents and river discharges. Submerged multiport diffusers were found to provide the greatest likelihood of meeting thermal standards in all receiving water environments

  3. Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems

    Directory of Open Access Journals (Sweden)

    Keizo Hirano

    2012-08-01

    Full Text Available The generation of complex neural circuits depends on the correct wiring of neurons with diverse individual characteristics. To understand the complexity of the nervous system, the molecular mechanisms for specifying the identity and diversity of individual neurons must be elucidated. The clustered protocadherins (Pcdh in mammals consist of approximately 50 Pcdh genes (Pcdh-α, Pcdh-β, and Pcdh-γ that encode cadherin-family cell surface adhesion proteins. Individual neurons express a random combination of Pcdh-α and Pcdh-γ, whereas the expression patterns for the Pcdh-β genes, 22 one-exon genes in mouse, are not fully understood. Here we show that the Pcdh-β genes are expressed in a 3’-polyadenylated form in mouse brain. In situ hybridization using a pan-Pcdh-β probe against a conserved Pcdh-β sequence showed widespread labeling in the brain, with prominent signals in the olfactory bulb, hippocampus, and cerebellum. In situ hybridization with specific probes for individual Pcdh-β genes showed their expression to be scattered in Purkinje cells from P10 to P150. The scattered expression patterns were confirmed by performing a newly developed single-cell 3’-RACE analysis of Purkinje cells, which clearly demonstrated that the Pcdh-β genes are expressed monoallelically and combinatorially in individual Purkinje cells. Scattered expression patterns of individual Pcdh-β genes were also observed in pyramidal neurons in the hippocampus and cerebral cortex, neurons in the trigeminal and dorsal root ganglion, GABAergic interneurons, and cholinergic neurons. Our results extend previous observations of diversity at the single-neuron level generated by Pcdh expression and suggest that the Pcdh-β cluster genes contribute to specifying the identity and diversity of individual neurons.

  4. Temporal patterns of rat behaviour in the central platform of the elevated plus maze. Comparative analysis between male subjects of strains with different basal levels of emotionality.

    Science.gov (United States)

    Casarrubea, M; Faulisi, F; Caternicchia, F; Santangelo, A; Di Giovanni, G; Benigno, A; Magnusson, M S; Crescimanno, G

    2016-08-01

    We have analyzed the temporal patterns of behaviour of male rats of the Wistar and DA/Han strains on the central platform of the elevated plus maze. The ethogram encompassed 10 behavioural elements. Durations, frequencies and latencies showed quantitative differences as to walking and sniffing activities. Wistar rats displayed significantly lower latency and significantly higher durations and frequencies of walking activities. DA/Han rats showed a significant increase of sniffing duration. In addition, DA/Han rats showed a significantly higher amount of time spent in the central platform. Multivariate T-pattern analysis revealed differences in the temporal organization of behaviour of the two rat strains. DA/Han rats showed (a) higher behavioural complexity and variability and (b) a significantly higher mean number of T-patterns than Wistar rats. Taken together, T-pattern analysis of behaviour in the centre of the elevated plus maze can noticeably improve the detection of subtle features of anxiety related behaviour. We suggest that T-pattern analysis could be used as sensitive tool to test the action of anxiolytic and anxiogenic manipulations. PMID:26247889

  5. Stationary wave patterns generated by an impurity moving with supersonic velocity through a Bose-Einstein condensate

    International Nuclear Information System (INIS)

    Formation of stationary three-dimensional (3D) wave patterns generated by a small pointlike impurity moving through a Bose-Einstein condensate with supersonic velocity is studied. Asymptotic formulae for a stationary far-field density distribution are obtained. Comparison with the three-dimensional numerical simulations demonstrates that these formulae are accurate enough already at the distances from the obstacle equal to a few wavelengths.

  6. Identify the consumption patterns of the second generation Chinese middle class. Does culture influence their consumption habits?

    OpenAIRE

    Liu, Kim Man

    2012-01-01

    Background: The 1978 political social reform in China has led to the emergence of the rapid and fast growing urban ‘middle class’ population. With the rise of the large population of middle class consumers, global market developers and opportunists are targeting this group of people to maximize their profits in developing countries. This research aimed to identify the consumption patterns of the second generation Chinese middle class and to investigate if their unique Chinese culture influenc...

  7. The Identification of Discriminating Patterns from 16S rRNA Gene to Generate Signature for Bacillus Genus.

    Science.gov (United States)

    More, Ravi P; Purohit, Hemant J

    2016-08-01

    The 16S ribosomal RNA (16S rRNA) gene has been widely used for the taxonomic classification of bacteria. A molecular signature is a set of nucleotide patterns, which constitute a regular expression that is specific to each particular taxon. Our main goal was to identify discriminating nucleotide patterns in 16S rRNA gene and then to generate signatures for taxonomic classification. To demonstrate our approach, we used the phylum Firmicutes as a model using representative taxa Bacilli (class), Bacillales (order), Bacillaceae (family), and Bacillus (genus), according to their dominance at each hierarchical taxonomic level. We applied combined composite vector and multiple sequence alignment approaches to generate gene-specific signatures. Further, we mapped all the patterns into the different hypervariable regions of 16S rRNA gene and confirmed the most appropriate distinguishing region as V3-V4 for targeted taxa. We also examined the evolution in discriminating patterns of signatures across taxonomic levels. We assessed the comparative classification accuracy of signatures with other methods (i.e., RDP Classifier, KNN, and SINA). Results revealed that the signatures for taxa Bacilli, Bacillales, Bacillaceae, and Bacillus could correctly classify isolate sequences with sensitivity of 0.99, 0.97, 0.94, and 0.89, respectively, and specificity close to 0.99. We developed signature-based software DNA Barcode Identification (DNA BarID) for taxonomic classification that is available at website http://www.neeri.res.in/DNA_BarID.htm . This pattern-based study provides a deeper understanding of taxon-specific discriminating patterns in 16S rRNA gene with respect to taxonomic classification. PMID:27104769

  8. High-harmonic generation from a coherent superposition of electronic states: Controlling interference patterns via short and long quantum orbits

    Science.gov (United States)

    Chelkowski, Szczepan; Bredtmann, Timm; Bandrauk, André D.

    2013-09-01

    Laser pump-probe schemes are explored numerically from a molecular time-dependent Schrödinger equation for monitoring attosecond electron motion by high-order-harmonic generation (HHG) from a coherent superposition of electronic states. Varying the time delay between the probe and pump pulse on an attosecond time scale alters the HHG signal, leading to universal interference patterns. By using an extended three-step recollision model, we show that various regular interference patterns in the HHG spectra, including continuous harmonic frequency redshifts as a function of pump-probe delay, are related to interference between specific pairs of short or long quantum orbits. For small excited-state population (regime A), interferences are controlled by electron-tunneling times, whereas for equal populations (regime B), recollision time control dominates thus allowing for control of the HHG process by the pump-probe delay time and by electron-state populations. We show that each specific pattern is closely related to the interference between pairs of specific (short or long) quantum orbits originating from a specific electron bound state. One can generate a specific pattern by varying the populations in the coherent superposition, the laser intensity, wavelength, and ionization potential of the electronic states.

  9. Mixed Methods Case Study of Generational Patterns in Responses to Shame and Guilt

    Science.gov (United States)

    Ng, Tony

    2013-01-01

    Moral socialization and moral learning are antecedents of moral motivation. As many as 4 generations interact in workplace and education settings; hence, a deeper understanding of the moral motivation of members of those generations is needed. The purpose of this convergent mixed methods case study was to understand the moral motivation of 5…

  10. Spatio-Temporal Stochastic Pattern Generator for ensemble prediction and ensemble data assimilation in geophysical applications

    CERN Document Server

    Tsyrulnikov, Michael

    2016-01-01

    A generator of spatio-temporal pseudo-random Gaussian fields that satisfy the "proportionality of scales" property (Tsyroulnikov 2001) is presented. The generator is a third-order in time stochastic differential equation with a pseudo-differential spatial operator defined on a limited area domain in Cartesian coordinate system. The spatial covariance functions of the generated fields belong to the Mat\\'ern class. The spatio-temporal covariances are non-separable. A spectral-space numerical solver is implemented and accelerated exploiting properties of real-world geophysical fields, in particular, smoothness of their spatial spectra. The generator is designed to simulate additive or multiplicative, or other spatio-temporal perturbations that represent uncertainties in numerical prediction models in geophysics. The program code of the generator is publicly available.

  11. Temporal and spatial patterns in wind stress and wind stress curl over the central Southern California Bight

    Science.gov (United States)

    Noble, Marlene A.; Rosenberger, Kurt J.; Rosenfeld, Leslie K.; Robertson, George L.

    2012-04-01

    In 2001, the U.S. Geological Survey, together with several other federal and municipal agencies, began a series of field programs to determine along and cross-shelf transport patterns over the continental shelves in the central Southern California Bight. As a part of these programs, moorings that monitor winds were deployed off the Palos Verdes peninsula and within San Pedro Bay for six 3-4 month summer and winter periods between 2001 and 2008. In addition, nearly continuous records of winds for this 7-year period were obtained from a terrestrial site at the coast and from a basin site offshore of the long-term coastal site. The mean annual winds are downcoast at all sites. The alongshelf components of wind stress, which are the largest part of the low-frequency wind stress fields, are well correlated between basin, shelf and coastal sites. On average, the amplitude of alongshelf fluctuations in wind stress are 3-4 times larger over the offshore basin, compared to the coastal site, irrespective of whether the fluctuations represent the total, or just the correlated portion of the wind stress field. The curl in the large-scale wind stress tends to be positive, especially in the winter season when the mean wind stress is downcoast and larger at the offshore basin site than at the beach. However, since the fluctuation in wind stress amplitudes are usually larger than the mean, periods of weak negative curl do occur, especially in the summer season when the largest normalized differences in the amplitude of wind stress fluctuations are found in the nearshore region of the coastal ocean. Even though the low-frequency wind stress field is well-correlated over the continental shelf and offshore basins, out to distances of 35 km or more from the coast, winds even 10 km inshore of the beach do not represent the coastal wind field, at least in the summer months. The seasonal changes in the spatial structures in wind stress amplitudes suggest that an assessment of the

  12. Near-field to far-field characterization of speckle patterns generated by disordered nanomaterials

    CERN Document Server

    Parigi, Valentina; Binard, Guillaume; Bourdillon, Céline; Maître, Agnès; Carminati, Rémi; Krachmalnicoff, Valentina; De Wilde, Yannick

    2016-01-01

    We study the intensity spatial correlation function of optical speckle patterns above a disordered dielectric medium in the multiple scattering regime. The intensity distributions are recorded by scanning near-field optical microscopy (SNOM) with sub-wavelength spatial resolution at variable distances from the surface in a range which spans continuously from the near-field (distance $ \\ll \\lambda $) to the far-field regime (distance $\\gg \\lambda $). The non-universal behavior at sub-wavelength distances reveals the connection between the near-field speckle pattern and the internal structure of the medium.

  13. Fuel operation of EDF nuclear fleet presentation of the centralized organization for operational engineering at the nuclear generation division

    International Nuclear Information System (INIS)

    The main feature of EDF Nuclear Fleet is the standardization, with 'series' of homogeneous plants (same equipment, fuel and operation technical documents). For fuel operation, this standardization is related to the concept of 'fuel management scheme' (typical fuel reloads with fixed number and enrichment of fresh assemblies) for a whole series of plants. The context of the Nuclear Fleet lead to the choice of a centralized organization for fuel engineering at the Nuclear Generation Division (DPN), located at UNIPE (National Department for Fleet Operation Engineering) in Lyon. The main features of this organization are the following: - Centralization of the engineering activities for fuel operation support in the Fuel Branch of UNIPE, - Strong real-time link with the nuclear sites, - Relations with various EDF Departments in charge of design, nuclear fuel supply and electricity production optimization. The purposes of the organization are: - Standardization of operational engineering services and products, - Autonomy with independent methods and computing tools, - Reactivity with a technical assistance for sites (24 hours 'hot line'), - Identification of different levels (on site and off site) to solve core operation problems, - Collection, analysis and valorization of operation feedback, - Contribution to fuel competence global management inside EDF. This paper briefly describes the organization. The main figures of annual engineering production are provided. A selection of examples illustrates the contribution to the Nuclear Fleet performance. (authors)

  14. Detection of planets in extremely weak central perturbation microlensing events via next-generation ground-based surveys

    CERN Document Server

    Chung, Sun-Ju; Koo, Jae-Rim

    2014-01-01

    Even though the recently discovered high-magnification event MOA-2010-BLG-311 had complete coverage over the peak, confident planet detection did not happen due to extremely weak central perturbations (fractional deviations of $\\lesssim 2\\%$). For confident detection of planets in extremely weak central perturbation (EWCP) events, it is necessary to have both high cadence monitoring and high photometric accuracy better than those of current follow-up observation systems.The next-generation ground-based observation project, KMTNet (Korea Microlensing Telescope Network), satisfies the conditions. We estimate the probability of occurrence of EWCP events with fractional deviations of $\\leq 2\\%$ in high-magnification events and the efficiency of detecting planets in the EWCP events using the KMTNet. From this study, we find that the EWCP events occur with a frequency of $> 50\\%$ in the case of $\\lesssim 100\\ M_{\\rm E}$ planets with separations of $0.2\\ {\\rm AU} \\lesssim d \\lesssim 20\\ {\\rm AU}$. We find that for m...

  15. Assessment of electricity generation and energy cost of wind energy conversion systems in north-central Nigeria

    International Nuclear Information System (INIS)

    Highlights: → The wind energy potential and economic analysis in selected six locations in north central part of Nigeria are investigated. → Economical evaluation of the wind energy in the selected sites was made by using the levelised cost method. → Locations that are suitable electricity generation and small scale applications are identified. - Abstract: In this study, the wind energy potential and economic analysis in selected six locations in north central part of Nigeria were investigated using wind speed data that span between 19 and 37 years measured at 10 m height. The performance of small to medium size commercial wind turbine models were examined and economic evaluation of the wind energy in the selected sites was made by using the levelised cost method. The results showed that the cost of energy production per kWh for the selected sites vary between cents 4.02 and cents 166.79. It was shown that Minna is most viable site while Bida is found to be least among the sites considered. Using three selected wind turbine models (in Minna) as case study, an increase in the escalation rate of operating and maintenance cost from 0% to 10%, lead to an increase in the unit energy cost by about 7%. It was further shown that by increasing the escalation rate of inflation from 0% to 5%, the cost of energy decreases by about 29% while the discount rate (return on investment) decreases from 11.54% to 6.23%.

  16. Gene Mutation Profiles in Primary Diffuse Large B Cell Lymphoma of Central Nervous System: Next Generation Sequencing Analyses.

    Science.gov (United States)

    Todorovic Balint, Milena; Jelicic, Jelena; Mihaljevic, Biljana; Kostic, Jelena; Stanic, Bojana; Balint, Bela; Pejanovic, Nadja; Lucic, Bojana; Tosic, Natasa; Marjanovic, Irena; Stojiljkovic, Maja; Karan-Djurasevic, Teodora; Perisic, Ognjen; Rakocevic, Goran; Popovic, Milos; Raicevic, Sava; Bila, Jelena; Antic, Darko; Andjelic, Bosko; Pavlovic, Sonja

    2016-01-01

    The existence of a potential primary central nervous system lymphoma-specific genomic signature that differs from the systemic form of diffuse large B cell lymphoma (DLBCL) has been suggested, but is still controversial. We investigated 19 patients with primary DLBCL of central nervous system (DLBCL CNS) using the TruSeq Amplicon Cancer Panel (TSACP) for 48 cancer-related genes. Next generation sequencing (NGS) analyses have revealed that over 80% of potentially protein-changing mutations were located in eight genes (CTNNB1, PIK3CA, PTEN, ATM, KRAS, PTPN11, TP53 and JAK3), pointing to the potential role of these genes in lymphomagenesis. TP53 was the only gene harboring mutations in all 19 patients. In addition, the presence of mutated TP53 and ATM genes correlated with a higher total number of mutations in other analyzed genes. Furthermore, the presence of mutated ATM correlated with poorer event-free survival (EFS) (p = 0.036). The presence of the mutated SMO gene correlated with earlier disease relapse (p = 0.023), inferior event-free survival (p = 0.011) and overall survival (OS) (p = 0.017), while mutations in the PTEN gene were associated with inferior OS (p = 0.048). Our findings suggest that the TP53 and ATM genes could be involved in the molecular pathophysiology of primary DLBCL CNS, whereas mutations in the PTEN and SMO genes could affect survival regardless of the initial treatment approach. PMID:27164089

  17. Gene Mutation Profiles in Primary Diffuse Large B Cell Lymphoma of Central Nervous System: Next Generation Sequencing Analyses

    Science.gov (United States)

    Todorovic Balint, Milena; Jelicic, Jelena; Mihaljevic, Biljana; Kostic, Jelena; Stanic, Bojana; Balint, Bela; Pejanovic, Nadja; Lucic, Bojana; Tosic, Natasa; Marjanovic, Irena; Stojiljkovic, Maja; Karan-Djurasevic, Teodora; Perisic, Ognjen; Rakocevic, Goran; Popovic, Milos; Raicevic, Sava; Bila, Jelena; Antic, Darko; Andjelic, Bosko; Pavlovic, Sonja

    2016-01-01

    The existence of a potential primary central nervous system lymphoma-specific genomic signature that differs from the systemic form of diffuse large B cell lymphoma (DLBCL) has been suggested, but is still controversial. We investigated 19 patients with primary DLBCL of central nervous system (DLBCL CNS) using the TruSeq Amplicon Cancer Panel (TSACP) for 48 cancer-related genes. Next generation sequencing (NGS) analyses have revealed that over 80% of potentially protein-changing mutations were located in eight genes (CTNNB1, PIK3CA, PTEN, ATM, KRAS, PTPN11, TP53 and JAK3), pointing to the potential role of these genes in lymphomagenesis. TP53 was the only gene harboring mutations in all 19 patients. In addition, the presence of mutated TP53 and ATM genes correlated with a higher total number of mutations in other analyzed genes. Furthermore, the presence of mutated ATM correlated with poorer event-free survival (EFS) (p = 0.036). The presence of the mutated SMO gene correlated with earlier disease relapse (p = 0.023), inferior event-free survival (p = 0.011) and overall survival (OS) (p = 0.017), while mutations in the PTEN gene were associated with inferior OS (p = 0.048). Our findings suggest that the TP53 and ATM genes could be involved in the molecular pathophysiology of primary DLBCL CNS, whereas mutations in the PTEN and SMO genes could affect survival regardless of the initial treatment approach. PMID:27164089

  18. Data Series Generation for CPS Plants Simulation; Generacion de Series para Simulacion de Centrales Termosolares

    Energy Technology Data Exchange (ETDEWEB)

    Ibanez, G.; Valenzuela, R. X.; Ramirez, L.; Polo, J.

    2014-02-01

    Due to the problems with the environment and other issues arising from the use of oil as the main source of energy, such as unstable politics and economics, there has been a growing interest in the development of alternative forms of energy over the last few years. In this field, the sun is a fundamental element, since any form of existing energy derives from it, directly or indirectly. Taking in to consideration all of these renewable energies, we have decided to focus on solar thermal energy, seeing as it will play a vital role in the future particularly in countries such as Spain that have great solar potential. Amid this form of renewable energy, the parabolic cylinder concentrator power plants are technologies with one of the most promising futures. Power plants with sufficient technological developments to compete with the other forms of energies and that have an extensive margin for improvement. These power plants are the subject of the investigations carried out in this project. This project will try to establish and standardize some of the necessary procedures for the process of data prior to the simulation of energy with these types of power plants. The final objective is to help create a regulation where all these procedures are gathered together, and one that can be used as a guide for future investigations on the viability of these power plants. To achieve this, this project is comprised of various phases where different necessary investigations will be carried out in order to define the different points of the regulation. Firstly, the different casuistries will be investigated when analyzing the behavior of the estimated input data. At this stage, the selected variable (global or direct radiation), as well as the procedure used for the generation of the Monthly Reference Value, will be taken in to account, differentiating it in to two different typologies. The best method for the adjustment of the estimated data obtained from the satellite images will

  19. Generation of Talc from the Mantle Wedge and its Role on the Subduction Dynamics in Central Mexico

    Science.gov (United States)

    Kim, Y.; Clayton, R. W.; Asimow, P. D.; Jackson, J. M.

    2013-05-01

    Geophysical evidence shows the existence of low-seismic velocity material at the surface of subducting slabs in subduction zones although its termination point may vary depending on various parameters such as its thermal state and slab dip angle. In central Mexican subduction zone, modeling of the teleseismic converted amplitudes of the horizontal oceanic crust previously revealed a thin (~4 km) low-velocity zone at the upper oceanic crust between the Cocos plate and the continental crust that appears to absorb nearly all of the strain between two plates. Using Vp/Vs as a function of S wave velocity (Vs) in a range of likely pressures (P) and temperatures (T) for candidate mineral phases, this thin layer in the flat slab region is determined to be enriched with hydrous (low-strength) minerals such as talc over the normal oceanic crustal compositions such as MORB-like gabbro. Based on the P-T curves for equilibria involving talc derived from available thermodynamic data, the generation of talc from the basaltic lithology of the oceanic crust subducting at the trench side is nearly impossible. Also, there is no clear evidence to explain the origin of the flat subduction based on the offshore anomalies, which may lead to the current configuration. We therefore propose that the talc-rich layer on top of the subducting plate is generated from the mantle wedge side during the slab flattening process coupled with trench rollback. The evolution of this low-strength zone has important implications for the dynamics of the subduction system including the flattening process of the slab as well as the geochemistry of the mantle wedge and arc in central Mexico.

  20. Characterization methods of nano-patterned surfaces generated by induction heating assisted injection molding

    DEFF Research Database (Denmark)

    Tang, Peter Torben; Ravn, Christian; Menotti, Stefano;

    2015-01-01

    An induction heating-assisted injection molding (IHAIM) process developed by the authors is used to replicate surfaces containing random nano-patterns. The injection molding setup is developed so that an induction heating system rapidly heats the cavity wall at rates of up to 10◦C/s. In order to...

  1. Infant dietary patterns and bone mass in childhood: the Generation R Study

    NARCIS (Netherlands)

    E.H. van den Hooven (Edith); D.H.M. Heppe (Denise); J.C. Kiefte-de Jong (Jessica); M.C. Medina-Gomez (Carolina); H.A. Moll (Henriëtte); A. Hofman (Albert); V.W.V. Jaddoe (Vincent); F. Rivadeneira Ramirez (Fernando); O.H. Franco (Oscar)

    2015-01-01

    textabstractConclusions: An infant dietary pattern characterized by high intakes of dairy and cheese, whole grains, and eggs is positively associated with bone development in childhood. Further research is needed to investigate the consequences for bone health in later life.Results: Higher adherence

  2. Generation and use of observational data patterns in the evaluation of data quality for AmeriFlux and FLUXNET

    Science.gov (United States)

    Pastorello, G.; Agarwal, D.; Poindexter, C.; Papale, D.; Trotta, C.; Ribeca, A.; Canfora, E.; Faybishenko, B.; Gunter, D.; Chu, H.

    2015-12-01

    The fluxes-measuring sites that are part of AmeriFlux are operated and maintained in a fairly independent fashion, both in terms of scientific goals and operational practices. This is also the case for most sites from other networks in FLUXNET. This independence leads to a degree of heterogeneity in the data sets collected at the sites, which is also reflected in data quality levels. The generation of derived data products and data synthesis efforts, two of the main goals of these networks, are directly affected by the heterogeneity in data quality. In a collaborative effort between AmeriFlux and ICOS, a series of quality checks are being conducted for the data sets before any network-level data processing and product generation take place. From these checks, a set of common data issues were identified, and are being cataloged and classified into data quality patterns. These patterns are now being used as a basis for implementing automation for certain data quality checks, speeding up the process of applying the checks and evaluating the data. Currently, most data checks are performed individually in each data set, requiring visual inspection and inputs from a data curator. This manual process makes it difficult to scale the quality checks, creating a bottleneck for the data processing. One goal of the automated checks is to free up time of data curators so they can focus on new or less common issues. As new issues are identified, they can also be cataloged and classified, extending the coverage of existing patterns or potentially generating new patterns, helping both improve existing automated checks and create new ones. This approach is helping make data quality evaluation faster, more systematic, and reproducible. Furthermore, these patterns are also helping with documenting common causes and solutions for data problems. This can help tower teams with diagnosing problems in data collection and processing, and also in correcting historical data sets. In this

  3. Pattern generation in the lobster (Panulirus) stomatogastric ganglion. II. Pyloric network simulation.

    Science.gov (United States)

    Hartline, D K

    1979-08-01

    1. Results from the companion paper were incorporated into a physiologically realistic computer model of the three principal cell types (PD/AB, LP, PY) of the pyloric network in the stomatogastric ganglion. Parameters for the model were mostly calculated (sometimes estimated) from experimental data rather than fitting the model to observed output patterns. 2. The initial run was successful in predicting several features of the pyloric pattern: the observed gap between PD and LP bursts, the appropriate sequence of the activity periods (PD, LP, PY), and a substantial PY burst not properly simulated by an earlier model. 3. The major discrepancy between model and observed patterns was the too-early occurrence of the PY burst, which resulted in a much shortened LP burst. Motivated by this discrepancy, additional investigations were made of PY properties. A hyperpolarization-enabled depolarization-activated hyperpolarizing conductance change was discovered which may make an important contribution to the late phase of PY activity in the normal burst cycle. Addition of this effect to the model brought its predictions more in line with observed patterns. 4. Other discrepancies between model and observation were instructive and are discussed. The findings force a substantial revision in previously held ideas on pattern production in the pyloric system. More weight must be given to functional properties of individual neurons and less to properties arising purely from network interactions. This shift in emphasis may be necessary in more complicated systems as well. 5. An example has been provided of the value quantitative modeling can be to network physiology. Only through rigorous quantitative testing can qualitative theories of how the nervous system operates be substantiated. PMID:227480

  4. Assembly-free genome comparison based on next-generation sequencing reads and variable length patterns

    OpenAIRE

    Comin, Matteo; Schimd, Michele

    2014-01-01

    Background With the advent of Next-Generation Sequencing technologies (NGS), a large amount of short read data has been generated. If a reference genome is not available, the assembly of a template sequence is usually challenging because of repeats and the short length of reads. When NGS reads cannot be mapped onto a reference genome alignment-based methods are not applicable. However it is still possible to study the evolutionary relationship of unassembled genomes based on NGS data. Results...

  5. Temporal patterns in Saturnidae (silk moth) and Sphingidae (hawk moth) assemblages in protected forests of central Uganda

    OpenAIRE

    Akite, Perpetra; Telford, Richard; Waring, Paul; Akol, Anne M.; Vandvik, Vigdis

    2015-01-01

    Forest-dependent biodiversity is threatened throughout the tropics by habitat loss and land-use intensification of the matrix habitats. We resampled historic data on two moth families, known to play central roles in many ecosystem processes, to evaluate temporal changes in species richness and community structure in three protected forests in central Uganda in a rapidly changing matrix. Our results show some significant declines in the moth species richness and the relative abundance and rich...

  6. The Importance of Peers: Assimilation Patterns among Second-generation Turkish Immigrants in Western Europe

    OpenAIRE

    Ali, S; Fokkema, T.

    2015-01-01

    The two dominant approaches to immigrant assimilation, segmented assimilation and "new" assimilation theories, have been successful at reporting and analyzing between-group differences in assimilation patterns. However, studies of assimilation generally do not address differences at the individual level. Current theories of assimilation cannot answer the simple question that gets to the heart of individual-level differences: how do you account for siblings in the same family assimilating in d...

  7. Spatial organization and state-dependent mechanisms for respiratory rhythm and pattern generation

    OpenAIRE

    Rybak, Ilya A.; Abdala, Ana P.L.; Markin, Sergey N.; Paton, Julian F. R.; Smith, Jeffrey C.

    2007-01-01

    The brainstem respiratory network can operate in multiple functional states engaging different state-dependent neural mechanisms. These mechanisms were studied in the in situ perfused rat brainstem–spinal cord preparation using sequential brainstem transections and administration of riluzole, a pharmacological blocker of persistent sodium current (INaP). Dramatic transformations in the rhythmogenic mechanisms and respiratory motor pattern were observed after removal of the pons and subsequent...

  8. Infant dietary patterns and bone mass in childhood: the Generation R Study

    OpenAIRE

    van den Hooven, E. H.; Heppe, D. H. M.; Kiefte-de Jong, J.C.; Medina-Gomez, C; Moll, H.A.; Hofman, A.; Jaddoe, V. W. V.; Rivadeneira, F.; Franco, O. H.

    2015-01-01

    Summary Early life nutrition affects peak bone mass attainment. In this prospective cohort study, children with high adherence to a “dairy and whole grains” pattern in infancy had higher bone mineral density at the age of 6 years. Although the observed effects are small, our study provides insight into mechanisms linking early nutrition to bone acquisition in childhood. Introduction Nutrition in early life may affect peak bone mass attainment. Previous studies on childhood nutrition and skele...

  9. Sustainability Assessment of a Self-Consumption Wood-Energy Chain on Small Scale for Heat Generation in Central Italy

    Directory of Open Access Journals (Sweden)

    Stefano Verani

    2015-06-01

    Full Text Available The sustainability of a small-scale self-consumption wood-energy chain for heat generation in central Italy was analyzed from a technical, economic and energetic point of view. A micro-chain was developed within the CRA-ING farm at Monterotondo (Rome, Italy: The purpose of this system was to produce biomass for supplying a heating plant within the CRA-ING property as a substitute for diesel fuel. A poplar short rotation coppice, established with clones AF2, AF6 and Monviso, fed the micro-chain. The rotation was biennial. The average plantation production (Mgd.m.·ha−1·year−1 was 10.2, with a maximum of 13.53 for the twin-rows AF2 and a minimum of 8.00 for the single-row Monviso. The economic assessment was based on the Net Present Value (NPV method and the equivalent annuity cost, and found an average saving of 15.60 €·GJ−1 of heat generated by the wood chips heating system in comparison with the diesel heating system over a 10 year lifetime of the thermal power plant. The energy assessment of the poplar plantation, carried out using the Gross Energy Requirements method, reported an energy output/input ratio of 12.3. The energy output/input ratio of the whole micro-chain was 4.5.

  10. Simple model for polar cap convection patterns and generation of theta auroras

    International Nuclear Information System (INIS)

    The simple addition of a uniform interplanetary magnetic field and the Earth's dipole magnetic field is used to evaluate electric field convection patterns over the polar caps that result from solar wind flow across open geomagnetic field lines. This model is found to account for observed polar-cap convection patterns as a function of the interplanetary magnetic field components B/sub y/ and B/sub z/. In particular, the model offers an explanation for sunward and antisunward convection over the polar caps for B/sub z/>0. Observed field-aligned current patterns within the polar cap and observed auroral arcs across the polar cap are also explained by the model. In addition, the model gives several predictions concerning the polar cap that should be testable. Effects of solar wind pressure and magnetospheric currents on magnetospheric electric and magnetic fields are neglected. That observed polar cap features are reproduced suggests that the neglected effects do not modify the large-scale topology of magnetospheric electric and magnetic fields along open polar cap field lines. Of course, the neglected effects significantly modify the magnetic geometry, so that the results of this paper are not quantitatively realistic and many details may be incorrect. Nevertheless, the model provides a simple explanation for many qualitative features of polar cap convection

  11. Concordance of MEG and fMRI patterns in adolescents during verb generation.

    Science.gov (United States)

    Wang, Yingying; Holland, Scott K; Vannest, Jennifer

    2012-04-01

    In this study we focused on direct comparison between the spatial distributions of activation detected by functional magnetic resonance imaging (fMRI) and localization of sources detected by magnetoencephalography (MEG) during identical language tasks. We examined the spatial concordance between MEG and fMRI results in 16 adolescents performing a three-phase verb generation task that involves repeating the auditorily presented concrete noun and generating verbs either overtly or covertly in response to the auditorily presented noun. MEG analysis was completed using a synthetic aperture magnetometry (SAM) technique, while the fMRI data were analyzed using the general linear model approach with random-effects. To quantify the agreement between the two modalities, we implemented voxel-wise concordance correlation coefficient (CCC) and identified the left inferior frontal gyrus and the bilateral motor cortex with high CCC values. At the group level, MEG and fMRI data showed spatial convergence in the left inferior frontal gyrus for covert or overt generation versus overt repetition, and the bilateral motor cortex when overt generation versus covert generation. These findings demonstrate the utility of the CCC as a quantitative measure of spatial convergence between two neuroimaging techniques. PMID:22365747

  12. Performance analysis of a Kalina cycle for a central receiver solar thermal power plant with direct steam generation

    International Nuclear Information System (INIS)

    Solar thermal power plants have attracted increasing interest in the past few years – with respect to both the design of the various plant components, and extending the operation hours by employing different types of storage systems. One approach to improve the overall plant efficiency is to use direct steam generation with water/steam as both the heat transfer fluid in the solar receivers and the cycle working fluid. This enables operating the plant with higher turbine inlet temperatures. Available literature suggests that it is feasible to use ammonia-water mixtures at high temperatures without corroding the equipment by using suitable additives with the mixture. The purpose of the study reported here was to investigate if there is any benefit of using a Kalina cycle for a direct steam generation, central receiver solar thermal power plant with high live steam temperature (450 °C) and pressure (over 100 bar). Thermodynamic performance of the Kalina cycle in terms of the plant exergy efficiency was evaluated and compared with a simple Rankine cycle. The rates of exergy destruction for the different components in the two cycles were also calculated and compared. The results suggest that the simple Rankine cycle exhibits better performance than the Kalina cycle when the heat input is only from the solar receiver. However, when using a two-tank molten-salt storage system as the primary source of heat input, the Kalina cycle showed an advantage over the simple Rankine cycle because of about 33 % reduction in the storage requirement. The solar receiver showed the highest rate of exergy destruction for both the cycles. The rates of exergy destruction in other components of the cycles were found to be highly dependent on the amount of recuperation, and the ammonia mass fraction and pressure at the turbine inlet. - Highlights: •Kalina cycle for a central receiver solar thermal power plant with direct steam generation. •Rankine cycle shows better plant exergy

  13. Are Dietary Patterns of Mothers during Pregnancy Related to Childrens Weight Status? Evidence from the Lifeways Cross-Generational Cohort Study

    OpenAIRE

    Murrin, Celine M; Mirjam M Heinen; Kelleher, Cecily C.

    2015-01-01

    Children's diet patterns are likely to be influenced by their mothers' diet pattern. The primary objective of this study was to examine whether children's adiposity could be influenced by diet patterns of mothers during pregnancy. A secondary objective was to study the relative influence of fathers' and children's dietary patterns on childhood adiposity. The design was a prospective cross-generational cohort study initiated with 1,124 mothers recruited during pregnancy. Self-reported question...

  14. Generating Frequent Patterns from Large Datasets using Improved Apriori and Support Chaining Method

    Directory of Open Access Journals (Sweden)

    P. Alagesh Kannan

    2015-08-01

    Full Text Available In this study, generating association rules with improved Apriori algorithm is proposed. Apriori is one of the most popular association rule mining algorithm that extracts frequent item sets from large databases. The traditional Apriori algorithm contains a major drawback. This algorithm wastes time in scanning the database to generate frequent item sets. The objective of any association rule mining algorithm is to generate association rules in a fast manner with great accuracy. In this study, a modification over the traditional Apriori algorithm is introduced. This improved Apriori algorithm searches frequent item sets from the large databases with less time. Experimental results shows that this improved Apriori algorithm reduces the scanning time as much as 67% and this algorithm is more efficient than the existing algorithm.

  15. Backswitch poling in lithium niobate for high-fidelity domain patterning and efficient blue light generation

    Science.gov (United States)

    Batchko, Robert G.; Shur, Vladimir Y.; Fejer, Martin M.; Byer, Robert L.

    1999-09-01

    In nonlinear optics applications employing quasiphase matching, short-pitch domain gratings are generally required for the efficient generation of visible and ultraviolet light. Here we introduce an improved electric-field poling technique, which incorporates spontaneous backswitching and leads to uniform short-pitch domain structures. The total volume of backswitched material, and hence the duty cycle of the backswitched domain grating, can be accurately controlled. First-order single-pass continuous-wave second harmonic generation of 60 mW at 460 nm is achieved at 6.1%/W efficiency in 0.5-mm-thick 4-μm-period backswitch-poled lithium niobate.

  16. Exact distribution of a pattern in a set of random sequences generated by a Markov source: applications to biological data

    Directory of Open Access Journals (Sweden)

    Regad Leslie

    2010-01-01

    Full Text Available Abstract Background In bioinformatics it is common to search for a pattern of interest in a potentially large set of rather short sequences (upstream gene regions, proteins, exons, etc.. Although many methodological approaches allow practitioners to compute the distribution of a pattern count in a random sequence generated by a Markov source, no specific developments have taken into account the counting of occurrences in a set of independent sequences. We aim to address this problem by deriving efficient approaches and algorithms to perform these computations both for low and high complexity patterns in the framework of homogeneous or heterogeneous Markov models. Results The latest advances in the field allowed us to use a technique of optimal Markov chain embedding based on deterministic finite automata to introduce three innovative algorithms. Algorithm 1 is the only one able to deal with heterogeneous models. It also permits to avoid any product of convolution of the pattern distribution in individual sequences. When working with homogeneous models, Algorithm 2 yields a dramatic reduction in the complexity by taking advantage of previous computations to obtain moment generating functions efficiently. In the particular case of low or moderate complexity patterns, Algorithm 3 exploits power computation and binary decomposition to further reduce the time complexity to a logarithmic scale. All these algorithms and their relative interest in comparison with existing ones were then tested and discussed on a toy-example and three biological data sets: structural patterns in protein loop structures, PROSITE signatures in a bacterial proteome, and transcription factors in upstream gene regions. On these data sets, we also compared our exact approaches to the tempting approximation that consists in concatenating the sequences in the data set into a single sequence. Conclusions Our algorithms prove to be effective and able to handle real data sets with

  17. Automated Learning of Subcellular Variation among Punctate Protein Patterns and a Generative Model of Their Relation to Microtubules.

    Directory of Open Access Journals (Sweden)

    Gregory R Johnson

    2015-12-01

    Full Text Available Characterizing the spatial distribution of proteins directly from microscopy images is a difficult problem with numerous applications in cell biology (e.g. identifying motor-related proteins and clinical research (e.g. identification of cancer biomarkers. Here we describe the design of a system that provides automated analysis of punctate protein patterns in microscope images, including quantification of their relationships to microtubules. We constructed the system using confocal immunofluorescence microscopy images from the Human Protein Atlas project for 11 punctate proteins in three cultured cell lines. These proteins have previously been characterized as being primarily located in punctate structures, but their images had all been annotated by visual examination as being simply "vesicular". We were able to show that these patterns could be distinguished from each other with high accuracy, and we were able to assign to one of these subclasses hundreds of proteins whose subcellular localization had not previously been well defined. In addition to providing these novel annotations, we built a generative approach to modeling of punctate distributions that captures the essential characteristics of the distinct patterns. Such models are expected to be valuable for representing and summarizing each pattern and for constructing systems biology simulations of cell behaviors.

  18. Consumption patterns and household hazardous solid waste generation in an urban settlement in Mexico

    International Nuclear Information System (INIS)

    Mexico is currently facing a crisis in the waste management field. Some efforts have just commenced in urban and in rural settlements, e.g., conversion of open dumps into landfills, a relatively small composting culture, and implementation of source separation and plastic recycling strategies. Nonetheless, the high heterogeneity of components in the waste, many of these with hazardous properties, present the municipal collection services with serious problems, due to the risks to the health of the workers and to the impacts to the environment as a result of the inadequate disposition of these wastes. A generation study in the domestic sector was undertaken with the aim of finding out the composition and the generation rate of household hazardous waste (HHW) produced at residences. Simultaneously to the generation study, a socioeconomic survey was applied to determine the influence of income level on the production of HHW. Results from the solid waste generation analysis indicated that approximately 1.6% of the waste stream consists of HHW. Correspondingly, it was estimated that in Morelia, a total amount of 442 ton/day of domestic waste are produced, including 7.1 ton of HHW per day. Furthermore, the overall amount of HHW is not directly related to income level, although particular byproducts do correlate. However, an important difference was observed, as the brands and the presentation sizes of goods and products used in each socioeconomic stratum varied

  19. Unveiling distribution patterns of freshwater phytoplankton by a next generation sequencing based approach

    Czech Academy of Sciences Publication Activity Database

    Eiler, A.; Drakare, S.; Bertilsson, S.; Pernthaler, J.; Peura, S.; Rofner, C.; Šimek, Karel; Yang, Y.; Znachor, Petr; Lindström, E.S.

    2013-01-01

    Roč. 8, č. 1 (2013), e53516. E-ISSN 1932-6203 R&D Projects: GA ČR(CZ) GA206/08/0015 Institutional support: RVO:60077344 Keywords : phytoplankton * next generation sequencing * diversity Subject RIV: EE - Microbiology, Virology Impact factor: 3.534, year: 2013

  20. A column generation-based heuristic for rostering with work patterns

    DEFF Research Database (Denmark)

    Lusby, Richard Martin; Dohn, Anders Høeg; Range, Troels Martin;

    2012-01-01

    approach, which utilizes column generation and variable fixing, to construct efficient rosters for a six-month time horizon. The time horizon is divided into smaller blocks, where overlaps between the blocks ensure continuity. The proposed methodology is able to circumvent one step of the conventional...

  1. Generation of Homogeneous and Patterned Electron Beams using a Microlens Array Laser-Shaping Technique

    Energy Technology Data Exchange (ETDEWEB)

    Halavanau, Aliaksei [NICADD, DeKalb; Edstrom, Dean [Fermilab; Gai, Wei [Argonne, HEP; Ha, Gwanghui [Argonne, HEP; Piot, Philippe [NICADD, DeKalb; Power, John [Argonne, HEP; Qiang, Gao [Unlisted, CN; Ruan, Jinhao [Fermilab; Santucci, James [Fermilab; Wisniewski, Eric [Argonne, HEP

    2016-06-01

    In photocathodes the achievable electron-beam parameters are controlled by the laser used to trigger the photoemission process. Non-ideal laser distribution hampers the final beam quality. Laser inhomogeneities, for instance, can be "amplified" by space-charge force and result in fragmented electron beams. To overcome this limitation laser shaping methods are routinely employed. In the present paper we demonstrate the use of simple microlens arrays to dramatically improve the transverse uniformity. We also show that this arrangement can be used to produce transversely-patterned electron beams. Our experiments are carried out at the Argonne Wakefield Accelerator facility.

  2. Impact of Thermal Plumes Generated by Occupant Simulators with Different Complexity of Body Geometry on Airflow Pattern in Rooms

    DEFF Research Database (Denmark)

    Zukowska, Daria; Melikov, Arsen Krikor; Popiolek, Zbigniew

    2008-01-01

    The impact of thermal plumes generated by human body simulators with different geometry on the airflow pattern in a full scale room with displacement ventilation (supply air temperature 21.6°C, total flow rate 80 L/s) was studied when two seated occupants were simulated first by two thermal manik...... with simplified geometry, such as cylinders, is insufficient for obtaining accurate results when studying airflow in rooms with displacement ventilation.......The impact of thermal plumes generated by human body simulators with different geometry on the airflow pattern in a full scale room with displacement ventilation (supply air temperature 21.6°C, total flow rate 80 L/s) was studied when two seated occupants were simulated first by two thermal...... manikins resembling accurately human body shape and then by two heated cylinders. The manikins and the cylinders had the same surface area of 1.63 m2 and the same heat generation of 73 W. CO2 supplied from the top of the heat sources was used for simulating bio-effluents. CO2 concentration was measured at...

  3. Generation of predictive price and trading volume patterns in a model of dynamically evolving free market supply and demand

    Directory of Open Access Journals (Sweden)

    J. K. Wang

    2001-01-01

    Full Text Available I present a model of stock market price fluctuations incorporating effects of share supply as a history-dependent function of previous purchases and share demand as a function of price deviation from moving averages. Price charts generated show intervals of oscillations switching amplitude and frequency suddenly in time, forming price and trading volume patterns well-known in market technical analysis. Ultimate price trends agree with traditional predictions for specific patterns. The consideration of dynamically evolving supply and demand in this model resolves the apparent contradiction with the Efficient Market Hypothesis: perceptions of imprecise equity values by a world of investors evolve over non-negligible periods of time, with dependence on price history.

  4. The spectral and polarization characteristics of the nonspherically decaying radiation generated by polarization currents with superluminally rotating distribution patterns

    CERN Document Server

    Ardavan, H; Singleton, J

    2003-01-01

    We present a theoretical study of the emission from a superluminal polarization current whose distribution pattern rotates (with an angular frequency $\\omega$) and oscillates (with a frequency $\\Omega $) at the same time, and which comprises both poloidal and toroidal components. This type of polarization current is found in recent practical machines designed to investigate superluminal emission. We find that the superluminal motion of the distribution pattern of the emitting current generates localized electromagnetic waves that do not decay spherically, i.e. that do not have an intensity diminishing like ${R_P}^{-2}$ with the distance $R_P$ from their source. The nonspherical decay of the focused wave packets that are emitted by the polarization currents does not contravene conservation of energy: the constructive interference of the constituent waves of such propagating caustics takes place within different solid angles on spheres of different radii ($R_P$) centred on the source. For a polarization current...

  5. Determine movement patterns and survival rates of Central Valley Chinook salmon, steelhead and their predators using acoustic tags.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The project’s objective is to document movement patterns and survival rates of Chinook salmon, steelhead, green sturgeon, and other fish from several sources in...

  6. Streamwise counter-rotating vortices generated by triangular leading edge pattern in flat plate boundary layer

    KAUST Repository

    Hasheminejad, S. M.

    2016-01-05

    A series of flow visualizations were conducted to qualitatively study the development of streamwise counter-rotating vortices over a flat plate induced by triangular patterns at the leading edge of a flat plate. The experiments were carried out for a Reynolds number based on the pattern wavelength (λ) of 3080. The results depict the onset, development and breakdown of the vortical structures within the flat plate boundary layer. Moreover, the effect of one spanwise array of holes with diameter of 0.2λ (=3 mm) was examined. This investigation was done on two different flat plates with holes placed at the location x/λ = 2 downstream of the troughs and peaks. The presence of holes after troughs does not show any significant effect on the vortical structures. However, the plate with holes after peaks noticeably delays the vortex breakdown. In this case, the “mushroom-like” vortices move away from the wall and propagate downstream with stable vortical structures. The vortex growth is halted further downstream but start to tilt aside.

  7. Student-generated questions during chemistry lectures: Patterns, self-appraisals, and relations with motivational beliefs and achievement

    Science.gov (United States)

    Bergey, Bradley W.

    Self-generated questions are a central mechanism for learning, yet students' questions are often infrequent during classroom instruction. As a result, little is known about the nature of student questioning during typical instructional contexts such as listening to a lecture, including the extent and nature of student-generated questions, how students evaluate their questions, and the relations among questions, motivations, and achievement. This study examined the questions undergraduate students (N = 103) generated during 8 lectures in an introductory chemistry course. Students recorded and appraised their question in daily question logs and reported lecture-specific self-efficacy beliefs. Self-efficacy, personal interest, goal orientations, and other motivational self-beliefs were measured before and after the unit. Primary analyses included testing path models, multiple regressions, and latent class analyses. Overall, results indicated that several characteristics of student questioning during lectures were significantly related to various motivations and achievement. Higher end-of-class self-efficacy was associated with fewer procedural questions and more questions that reflected smaller knowledge deficits. Lower exam scores were associated with questions reflecting broader knowledge deficits and students' appraisals that their questions had less value for others than for themselves. Individual goal orientations collectively and positively predicted question appraisals. The questions students generated and their relations with motivational variables and achievement are discussed in light of the learning task and academic context.

  8. Locations and patterns of meiotic recombination in two-generation pedigrees

    OpenAIRE

    Roberson Elisha DO; Ting Jason C; Currier Duane G; Pevsner Jonathan

    2009-01-01

    Abstract Background Meiotic crossovers are the major mechanism by which haplotypes are shuffled to generate genetic diversity. Previously available methods for the genome-wide, high-resolution identification of meiotic crossover sites are limited by the laborious nature of the assay (as in sperm typing). Methods Several methods have been introduced to identify crossovers using high density single nucleotide polymorphism (SNP) array technologies, although programs are not widely available to i...

  9. Time-resolved measurements with streaked diffraction patterns from electrons generated in laser plasma wakefield

    Science.gov (United States)

    He, Zhaohan; Nees, John; Hou, Bixue; Krushelnick, Karl; Thomas, Alec; Beaurepaire, Benoît; Malka, Victor; Faure, Jérôme

    2013-10-01

    Femtosecond bunches of electrons with relativistic to ultra-relativistic energies can be robustly produced in laser plasma wakefield accelerators (LWFA). Scaling the electron energy down to sub-relativistic and MeV level using a millijoule laser system will make such electron source a promising candidate for ultrafast electron diffraction (UED) applications due to the intrinsic short bunch duration and perfect synchronization with the optical pump. Recent results of electron diffraction from a single crystal gold foil, using LWFA electrons driven by 8-mJ, 35-fs laser pulses at 500 Hz, will be presented. The accelerated electrons were collimated with a solenoid magnetic lens. By applying a small-angle tilt to the magnetic lens, the diffraction pattern can be streaked such that the temporal evolution is separated spatially on the detector screen after propagation. The observable time window and achievable temporal resolution are studied in pump-probe measurements of photo-induced heating on the gold foil.

  10. Large-scale patterns of Quercus ilex, Quercus suber, and Quercus pyrenaica regeneration in central-western Spain

    DEFF Research Database (Denmark)

    Plieninger, Tobias; Rolo, Víctor; Moreno, Gerardo

    2010-01-01

    In Central-Western Spain, forests and woodlands composed of Quercus sp. support outstanding levels of biodiversity, but there is increasing concern about their long-term persistence due to a lack of regeneration. We hypothesize that this regenerative lack is operating on a large geographic scale...

  11. PLAP efficiently generates mature antigenic peptides in vitro but in patterns distinct from ERAP11

    OpenAIRE

    Georgiadou, Dimitra; Hearn, Arron; Evnouchidou, Irini; Chroni, Angeliki; Leondiadis, Leondios; Ian A York; Rock, Kenneth L.; Stratikos, Efstratios

    2010-01-01

    All three members of the oxytocinase sub-family of M1 aminopeptidases, ERAP1 (ERAAP), ERAP2 and PLAP (IRAP), have been implicated in the generation of MHC class I-presented peptides. ERAP1 and 2 trim peptides in the endoplasmic reticulum for direct presentation whereas PLAP has been recently implicated in cross presentation. The best characterized member of the family, ERAP1, has unique enzymatic properties that fit well with its role in antigen processing. ERAP1 can trim a large variety of l...

  12. Direct patterning of vortex generators on a fiber tip using a focused ion beam.

    Science.gov (United States)

    Vayalamkuzhi, Pramitha; Bhattacharya, Shanti; Eigenthaler, Ulrike; Keskinbora, Kahraman; Samlan, C T; Hirscher, Michael; Spatz, Joachim P; Viswanathan, Nirmal K

    2016-05-15

    The realization of spiral phase optical elements on the cleaved end of an optical fiber by focused ion beam milling is presented. A focused Ga+ ion beam with an acceleration voltage of 30 keV is used to etch continuous spiral phase plates and fork gratings directly on the tip of the fiber. The phase characteristics of the output beam generated by the fabricated structures measured via an interference experiment confirmed the presence of phase singularity in the output beam. The devices are expected to be promising candidates for all-fiber beam shaping and optical trapping applications. PMID:27176945

  13. Self-organization in patch pattern dynamics along the climatic gradient of the Judean lowland in central Israel

    Energy Technology Data Exchange (ETDEWEB)

    Shoshany, M.

    2009-07-01

    The role of Self-organization in the formation, evolution and recovery of natural systems from organismic to global scale cannot be over-estimated. Many of these systems represent a type of patch pattern dynamic behavior where patches are created, spread, expanded, aggregated, dissected and dissolved in parallel, forming myriad patterns through their evolution. Self-organization concern the functioning of intrinsic mechanisms which intrinsically regulate pattern changes leading these systems toward order following phases of disturbance or structural transformation (e.g., from herbaceous ecosystem to shrub lands). The aim of this paper is to present a new approach of Converging Self-Organization (CSO) coupling between information from geo simulated self-organization and remote sensing data. (Author) 4 refs.

  14. Patterns of waste generation, treatment and disposal in the chemical and allied industries in Ghana

    Directory of Open Access Journals (Sweden)

    Osei-Wusu Achaw

    2012-09-01

    Full Text Available Environmental pollution and degradation in urban Ghana has been on the increase as a result of the nations drive towards industrialization, a generally weak regulatory regime, and a lack of capacity to manage the environment. This situation is affecting the well-being and livelihood of affected communities. As part of an effort to address the issue, a thirteen (13 item questionnaire was designed and distributed to seventy (70 companies in the chemical and allied industry to solicit and analyze data and information on the their waste management situation. Forty-seven, representing 67.1%, of the distributed questionnaires were completed and returned. The responses were analyzed using tables, percentages and bar charts. The results revealed that while 80.9% of the respondents generate waste as a result of the operation of the plants, 23.3% directly dump their waste into the environment without any prior treatment. Only one company was found that incinerate its waste, and only four (8.5% had comprehensive waste water treatment plants. The low numbers of companies treating the waste they generate prior to disposal means that the chemical and allied industry is contributing to the environmental pollution and degradation in the country.

  15. A novel approach to locomotion learning: Actor-Critic architecture using central pattern generators and dynamic motor primitives

    OpenAIRE

    Cai eLi; Robert eLowe; Tom eZiemke

    2014-01-01

    In this article, we propose an architecture of a bio-inspired controller that addresses the problem of learning different locomotion gaits for different robot morphologies. The modelling objective is split into two: baseline motion modelling and dynamics adaptation. Baseline motion modelling aims to achieve fundamental functions of a certain type of locomotion and dynamics adaptation provides a ``reshaping function for adapting the baseline motion to desired motion. Based on this assumption, ...

  16. Patterns of death in the first and second generation immigrants from selected Middle Eastern countries in California.

    Science.gov (United States)

    Nasseri, Kiumarss; Moulton, Lawrence H

    2011-04-01

    Migrant studies in the United States (US) have rarely covered the Middle Eastern population (ME), and have never distinguished the first and second generations born in the US. This study aims to describe the mortality patterns of ME immigrants by origin, acculturation, and generation. Death certificates issued from 1997 through 2004 were used to calculate, for Middle Eastern immigrants, the proportional odds ratios (POR) for major causes of death, with comparison to non-Hispanic Whites born in the US to US-born parents. First generation immigrants had higher odds for colorectal cancers, diabetes, and diseases of the heart, while their odds for chronic obstructive pulmonary disease (COPD) and suicide were lower. Men had higher odds for all cancers combined, cancers of the lymphatics, and pancreas. Women had lower odds for lung cancer, and dementia, and higher odds for breast cancer. The second generation men had higher odds for all cancers combined, and diseases of the heart, whereas women had lower odds for lung cancer and cerebrovascular accidents. Higher odds for colorectal cancers and lower odds for COPD were noted in both sexes. Some of the observed differences may be based on ethnic characteristics, including genetic makeup, early exposures, and culturally determined values. Time since immigration is associated with convergence of most odds to that of the native population. PMID:19621261

  17. Generation of three-dimensional patterns through wave interaction in a model of free surface swirling flow

    International Nuclear Information System (INIS)

    The free surface flow in a cylindrical tank over a rotating bottom is known to support spectacular three-dimensional patterns, including deformation of the inner free surface into the shape of rotating polygons and sloshing behavior of the upper free surface (e.g. Iga et al 2014 Fluid Dyn. Res. 46 031409). Through a stability analysis of a simplified model of this flow, we show that such patterns can be explained as a resonance mechanism involving different families of waves. The approach extends a previous work (Tophøj et al 2013 Phys. Rev. Lett. 110 194502) which explained the rotating polygons as an interaction between gravity waves and centrifugal waves, under the assumption that the base flow can be modeled as a potential vortex. We show that this previous model is justified for strong rotation rates (Dry-Potential case), and that for weaker rotations it can be improved by introducing an inner vortex core in solid-body rotation, which either extends to the center of the plate (Wet case) or surrounds a dry central region (Dry-Composite case). The study of this improved model predicts two new kinds of instabilities. The first occurs at low rotations (Wet case) and results from an interaction between gravity waves and the Kelvin–Kirchhoff wave (namely, oscillation of the boundary of the vortex core). This instability is proposed to be at the origin of the sloshing phenomenon. The second new instability occurs, for moderate rotations, (Dry-Composite case) as an interaction between gravity waves and a ‘Kelvin-Centrifugal’ wave characterized by deformation of the inner surface and the vortex core boundary in opposite directions. This instability exists for all azimuthal wave numbers starting from m = 1, this case corresponding to a ‘monogon’ pattern. (paper)

  18. Comparison between 3D eddy current patterns in tokamak in-vessel components generated by disruptions

    International Nuclear Information System (INIS)

    During plasma disruption events in Tokamaks, a large amount of magnetic energy is associated to the transfer of plasma current into eddy currents in the passive structures. In the ITER program two design concepts have been proposed. One approach (ITER CDA design) is based on copper stabilization loops (i.e., twin loops) attached to box-shaped blanket segments, electrically and mechanically separated along the toroidal direction. For another design concept (ITER EDA design) based on lower plasma elongation there is no need for specific stabilization loops. The passive stabilization is obtained by toroidally continuous components (i.e., the plasma facing wall of the blanket segments allows a continuity along the toroidal direction). Consequently, toroidal currents flow, when electromagnetic transients occur. Electromagnetic loads appear in the blanket structures in case of plasma disruptions and/or vertical displacement events either for the ITER CDA design concept or for the ITER EDA design concept. In this paper the influence of the in-vessel design configuration concepts--insulated segments or electrically continuous structures--in terms of magnetic shielding and electric insulation on the magnitude and the flow pattern of the eddy currents is investigated. This investigation will allow a performance evaluation of the two proposed design concepts

  19. Large-scale Generation of Patterned Bubble Arrays on Printed Bi-functional Boiling Surfaces

    Science.gov (United States)

    Choi, Chang-Ho; David, Michele; Gao, Zhongwei; Chang, Alvin; Allen, Marshall; Wang, Hailei; Chang, Chih-Hung

    2016-04-01

    Bubble nucleation control, growth and departure dynamics is important in understanding boiling phenomena and enhancing nucleate boiling heat transfer performance. We report a novel bi-functional heterogeneous surface structure that is capable of tuning bubble nucleation, growth and departure dynamics. For the fabrication of the surface, hydrophobic polymer dot arrays are first printed on a substrate, followed by hydrophilic ZnO nanostructure deposition via microreactor-assisted nanomaterial deposition (MAND) processing. Wettability contrast between the hydrophobic polymer dot arrays and aqueous ZnO solution allows for the fabrication of heterogeneous surfaces with distinct wettability regions. Heterogeneous surfaces with various configurations were fabricated and their bubble dynamics were examined at elevated heat flux, revealing various nucleate boiling phenomena. In particular, aligned and patterned bubbles with a tunable departure frequency and diameter were demonstrated in a boiling experiment for the first time. Taking advantage of our fabrication method, a 6 inch wafer size heterogeneous surface was prepared. Pool boiling experiments were also performed to demonstrate a heat flux enhancement up to 3X at the same surface superheat using bi-functional surfaces, compared to a bare stainless steel surface.

  20. Control Theoretic Modeling and Generated Flow Patterns of a Fish-Tail Robot

    Science.gov (United States)

    Massey, Brian; Morgansen, Kristi; Dabiri, Dana

    2003-11-01

    Many real-world engineering problems involve understanding and manipulating fluid flows. One of the challenges to further progress in the area of active flow control is the lack of appropriate models that are amenable to control-theoretic studies and algorithm design and also incorporate reasonably realistic fluid dynamic effects. We focus here on modeling and model-verification of bio-inspired actuators (fish-fin type structures) used to control fluid dynamic artifacts that will affect speed, agility, and stealth of Underwater Autonomous Vehicles (UAVs). Vehicles using fish-tail type systems are more maneuverable, can turn in much shorter and more constrained spaces, have lower drag, are quieter and potentially more efficient than those using propellers. We will present control-theoretic models for a simple prototype coupled fluid and mechanical actuator where fluid effects are crudely modeled by assuming only lift, drag, and added mass, while neglecting boundary effects. These models will be tested with different control input parameters on an experimental fish-tail robot with the resulting flow captured with DPIV. Relations between the model, the control function choices, the obtained thrust and drag, and the corresponding flow patterns will be presented and discussed.

  1. Broad and ultra-flattened supercontinuum generation in the visible wavelengths based on the fundamental mode of photonic crystal fibre with central holes

    Institute of Scientific and Technical Information of China (English)

    Yuan Jin-Hui; Sang Xin-Zhu; Yu Chong-Xiu; Xin Xiang-Jun; Shen Xiang-Wei; Zhang Jin-Long; Zhou Gui-Yao; Li Shu-Guang; Hou Lan-Tian

    2011-01-01

    By coupling a train of femtosecond pulses with 100 fs pulse width at a repetition rate of 76 MHz generated by a mode-locked Ti: sapphire laser into the fundamental mode of photonic crystal fibre (PCF) with central holes fabricated through extracting air from the central hole, the broad and ultra-flattened supercontinuum (SC) in the visible wavelengths is generated. When the fundamental mode experiences an anomalous dispersion regime, three phases in the SC generation process are primarily presented. The SC generation (SCG) in the wavelength range from 470 nm to 805 nm does not emerge significant ripples due to a higher pump peak power and the corresponding mode fields at different wavelengths are observed using Bragg gratings. The relative intensity fluctuations of output spectrum in the wavelength ranges of 530 nm to 640 nm and 543 nm to 590 nm are only 0.028 and 0.0071, respectively.

  2. Temporal patterns in Saturnidae (silk moth) and Sphingidae (hawk moth) assemblages in protected forests of central Uganda.

    Science.gov (United States)

    Akite, Perpetra; Telford, Richard J; Waring, Paul; Akol, Anne M; Vandvik, Vigdis

    2015-04-01

    Forest-dependent biodiversity is threatened throughout the tropics by habitat loss and land-use intensification of the matrix habitats. We resampled historic data on two moth families, known to play central roles in many ecosystem processes, to evaluate temporal changes in species richness and community structure in three protected forests in central Uganda in a rapidly changing matrix. Our results show some significant declines in the moth species richness and the relative abundance and richness of forest-dependent species over the last 20-40 years. The observed changes in species richness and composition among different forests, ecological types, and moth groups highlight the need to repeatedly monitor biodiversity even within protected and relatively intact forests. PMID:25937916

  3. Resolution Improvement and Pattern Generator Development for theMaskless Micro-Ion-Beam Reduction Lithography System

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Ximan

    2006-05-18

    strategies have been studied. The dependence of the throughput with the exposure field size and the speed of the mechanical stage has been investigated. In order to perform maskless lithography, different micro-fabricated pattern generators have been developed for the MMRL system. Ion beamlet switching has been successfully demonstrated on the MMRL system. A positive bias voltage around 10 volts is sufficient to switch off the ion current on the micro-fabricated pattern generators. Some unexpected problems, such as the high-energy secondary electron radiations, have been discovered during the experimental investigation. Thermal and structural analysis indicates that the aperture displacement error induced by thermal expansion can satisfy the 3{delta} CD requirement for lithography nodes down to 25 nm. The cross-talking effect near the surface and inside the apertures of the pattern generator has been simulated in a 3-D ray-tracing code. New pattern generator design has been proposed to reduce the cross-talking effect. In order to eliminate the surface charging effect caused by the secondary electrons, a new beam-switching scheme in which the switching electrodes are immersed in the plasma has been demonstrated on a mechanically fabricated pattern generator.

  4. On the processes generating latitudinal richness gradients: identifying diagnostic patterns and predictions

    Energy Technology Data Exchange (ETDEWEB)

    Hurlbert, Allen H.; Stegen, James C.

    2014-12-02

    Many processes have been put forward to explain the latitudinal gradient in species richness. Here, we use a simulation model to examine four of the most common hypotheses and identify patterns that might be diagnostic of those four hypotheses. The hypotheses examined include (1) tropical niche conservatism, or the idea that the tropics are more diverse because a tropical clade origin has allowed more time for diversification in the tropics and has resulted in few species adapted to extra-tropical climates. (2) The productivity, or energetic constraints, hypothesis suggests that species richness is limited by the amount of biologically available energy in a region. (3) The tropical stability hypothesis argues that major climatic fluctuations and glacial cycles in extratropical regions have led to greater extinction rates and less opportunity for specialization relative to the tropics. (4) Finally, the speciation rates hypothesis suggests that the latitudinal richness gradient arises from a parallel gradient in rates of speciation. We found that tropical niche conservatism can be distinguished from the other three scenarios by phylogenies which are more balanced than expected, no relationship between mean root distance and richness across regions, and a homogeneous rate of speciation across clades and through time. The energy gradient, speciation gradient, and disturbance gradient scenarios all exhibited phylogenies which were more imbalanced than expected, showed a negative relationship between mean root distance and richness, and diversity-dependence of speciation rate estimates through time. Using Bayesian Analysis of Macroevolutionary Mixtures on the simulated phylogenies, we found that the relationship between speciation rates and latitude could distinguish among these three scenarios. We emphasize the importance of considering multiple hypotheses and focusing on diagnostic predictions instead of predictions that are consistent with more than one hypothesis.

  5. Internalization of externalities in the generation costs of electric power centrals of carbon, combined cycle and nuclear; Internalizacion de externalidades en los costos de generacion de centrales electricas de carbon, ciclo combinado y nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Gomez R, M.C. [Universidad Anahuac del Norte (Mexico); Palacios H, J.; Ramirez S, R.; Alonso V, G. [ININ, Carretera Mexico-Toluca Km. 36.5 Ocoyoacac 52750 Edo. de Mexico (Mexico)]. e-mail: fgrivera@avantel.net

    2007-07-01

    The technologies of electric power generation that use fossil fuels, they incorporate in the Even Total Cost of Generation (CTNG) only the direct costs of generation (investment, fuel costs, operation costs and maintenance). nevertheless, the nuclear energy incorporates besides the direct costs, the externalities that causes to the human health and the environment. In this work the CTNG is calculated that incorporates the externalities, of a thermoelectric power station of coal, a plant of combined cycle and of four reactors of Generation III (ABWR, ACR, AP1000 and EPR). The obtained results show that the nuclear power station has smaller CTNG that the technologies that use fossil fuels. It is important to stand out that they are only considering the externalities of the stage of electricity generation, for what the mining phase and transport of the fuel toward the central are not considered in the present document. (Author)

  6. Unveiling distribution patterns of freshwater phytoplankton by a next generation sequencing based approach.

    Directory of Open Access Journals (Sweden)

    Alexander Eiler

    Full Text Available The recognition and discrimination of phytoplankton species is one of the foundations of freshwater biodiversity research and environmental monitoring. This step is frequently a bottleneck in the analytical chain from sampling to data analysis and subsequent environmental status evaluation. Here we present phytoplankton diversity data from 49 lakes including three seasonal surveys assessed by next generation sequencing (NGS of 16S ribosomal RNA chloroplast and cyanobacterial gene amplicons and also compare part of these datasets with identification based on morphology. Direct comparison of NGS to microscopic data from three time-series showed that NGS was able to capture the seasonality in phytoplankton succession as observed by microscopy. Still, the PCR-based approach was only semi-quantitative, and detailed NGS and microscopy taxa lists had only low taxonomic correspondence. This is probably due to, both, methodological constraints and current discrepancies in taxonomic frameworks. Discrepancies included Euglenophyta and Heterokonta that were scarce in the NGS but frequently detected by microscopy and Cyanobacteria that were in general more abundant and classified with high resolution by NGS. A deep-branching taxonomically unclassified cluster was frequently detected by NGS but could not be linked to any group identified by microscopy. NGS derived phytoplankton composition differed significantly among lakes with different trophic status, showing that our approach can resolve phytoplankton communities at a level relevant for ecosystem management. The high reproducibility and potential for standardization and parallelization makes our NGS approach an excellent candidate for simultaneous monitoring of prokaryotic and eukaryotic phytoplankton in inland waters.

  7. Linking Spatial Patterns of Groundwater Table Dynamics and Streamflow Generation Processes in a Small Developed Catchment

    Directory of Open Access Journals (Sweden)

    Natalie Orlowski

    2014-10-01

    Full Text Available Knowledge about water flow paths is essential for understanding biogeochemical fluxes in developed agricultural landscapes, i.e., the input of nutrients into surface waters, soil erosion, or pesticide fate. Several methods are available to study rainfall-runoff processes and flux partitioning: hydrometric based approaches, chemical tracers, modeling, and stable isotope applications. In this study a multi-method approach was conducted to gain insights into the hydrological fluxes and process understanding within the complex anthropogenic-influenced catchment of the Vollnkirchener Bach, Germany. Our results indicate that the catchment responds differently to precipitation input signals and dominant runoff-generation processes change throughout the year. Rainfall-induced runoff events during dry periods are characterized by a temporarily active combined sewer overflow. During stormflow, a large contribution of fast event water is observed. At low flow conditions losing and gaining conditions occur in parallel. However, when catchment’s moisture conditions are high, an ephemeral source from clay shale-graywacke dominated forested sites becomes active. The study reveals that the collection of detailed distributed hydrometric data combined with isotopic tracers, provides fundamental information on the complex catchment behavior, which can finally be utilized for conceptualizing water fluxes at a small catchment scale.

  8. Investigating Theoretical PV Energy Generation Patterns with Their Relation to the Power Load Curve in Poland

    Directory of Open Access Journals (Sweden)

    Jakub Jurasz

    2016-01-01

    Full Text Available Polish energy sector is (almost from its origin dominated by fossil fuel feed power. This situation results from an abundance of relatively cheap coal (hard and lignite. Brown coal due to its nature is the cheapest energy source in Poland. However, hard coal which fuels 60% of polish power plants is picking up on prices and is susceptible to the coal imported from neighboring countries. Forced by the European Union (EU regulations, Poland is struggling at achieving its goal of reaching 15% of energy consumption from renewable energy sources (RES by 2020. Over the year 2015, RES covered 11.3% of gross energy consumption but this generation was dominated by solid biomass (over 80%. The aim of this paper was to answer the following research questions: What is the relation of irradiation values to the power load on a yearly and daily basis? and how should photovoltaics (PV be integrated in the polish power system? Conducted analysis allowed us to state that there exists a negative correlation between power demand and irradiation values on a yearly basis, but this is likely to change in the future. Secondly, on average, daily values of irradiation tend to follow power load curve over the first hours of the day.

  9. Second-generation antipsychotics in a tertiary care hospital: prescribing patterns, metabolic profiles, and drug interactions.

    Science.gov (United States)

    Niedrig, David F; Gött, Carmen; Fischer, Anja; Müller, Sabrina T; Greil, Waldemar; Bucklar, Guido; Russmann, Stefan

    2016-01-01

    We carried out an observational study that analyzed population characteristics, metabolic profiles, potentially interacting pharmacotherapy, and related adverse events in second-generation antipsychotics (SGAs) users of a tertiary care hospital. Within our pharmacoepidemiological database derived from electronic medical records of 82,358 hospitalizations, we identified 1136 hospitalizations contributing 9165 patient-days with exposure to SGA. Blood pressure, blood glucose, lipids, and BMI had been documented in 97.7, 75.7, 24.6, and 77.4% of hospitalizations, respectively. Among these, the prevalence of hypertension, hyperglycemia, dyslipidemia, and BMI 30 kg/m or more was 36.9, 22.6, 61.1, and 23.1%, respectively. A total of 63.4, 70.8, and 37.1% of SGA users with hyperglycemia, dyslipidemia, and hypertension, respectively, received no pharmacotherapy for these conditions. We identified 614 patient-days with SGA plus formally contraindicated comedication and another 1066 patient-days with other high-risk combinations for QTc prolongation. Among those there was one case with associated neutropenia and four cases with abnormal QTc interval. However, specific monitoring for such adverse events was not documented in 45.5% of hospitalizations with contraindicated and 89.8% with high-risk QTc-prolonging combinations. Our study identified targets for improved monitoring and management in SGA users. These may be implemented as automated alerts into electronic prescribing systems and thereby efficiently support safer pharmacotherapy in clinical practice. PMID:26473524

  10. Patterns in abundance and diversity of faecally dispersed parasites of tiger in Tadoba National Park, central India

    OpenAIRE

    Jog Maithili M; Ranade Sachin P; Goel Shantanu S; Marathe Rahul R; Watve Milind G

    2002-01-01

    Abstract Background Importance of parasites in ecological and evolutionary interactions is being increasingly recognized. However, ecological data on parasites of important host species is still scanty. We analyze the patterns seen in the faecal parasites of tigers in the Tadoba National Park, India, and speculate on the factors and processes shaping the parasite community and the possible implications for tiger ecology. Results The prevalence and intensities were high and the parasite commun...

  11. Congruent phylogeographical patterns of eight tree species in Atlantic Central Africa provide insights into the past dynamics of forest cover

    OpenAIRE

    Dauby, G.; Duminil, J.; Heuertz, Miryam; Koffi, G. K.; T. Stévart; Olivier J Hardy

    2014-01-01

    Cycles of Quaternary climatic change are assumed to be major drivers of African rainforest dynamics and evolution. However, most hypotheses on past vegetation dynamics relied on palaeobotanical records, an approach lacking spatial resolution, and on current patterns of species diversity and endemism, an approach confounding history and environmental determinism. In this context, a comparative phylogeographical study of rainforest species represents a complementary approach because Pleistocene...

  12. Detection of planets in extremely weak central perturbation microlensing events via next-generation ground-based surveys

    International Nuclear Information System (INIS)

    Even though the recently discovered high-magnification event MOA-2010-BLG-311 had complete coverage over its peak, confident planet detection did not happen due to extremely weak central perturbations (EWCPs, fractional deviations of ≲ 2%). For confident detection of planets in EWCP events, it is necessary to have both high cadence monitoring and high photometric accuracy better than those of current follow-up observation systems. The next-generation ground-based observation project, Korea Microlensing Telescope Network (KMTNet), satisfies these conditions. We estimate the probability of occurrence of EWCP events with fractional deviations of ≤2% in high-magnification events and the efficiency of detecting planets in the EWCP events using the KMTNet. From this study, we find that the EWCP events occur with a frequency of >50% in the case of ≲ 100 M E planets with separations of 0.2 AU ≲ d ≲ 20 AU. We find that for main-sequence and sub-giant source stars, ≳ 1 M E planets in EWCP events with deviations ≤2% can be detected with frequency >50% in a certain range that changes with the planet mass. However, it is difficult to detect planets in EWCP events of bright stars like giant stars because it is easy for KMTNet to be saturated around the peak of the events because of its constant exposure time. EWCP events are caused by close, intermediate, and wide planetary systems with low-mass planets and close and wide planetary systems with massive planets. Therefore, we expect that a much greater variety of planetary systems than those already detected, which are mostly intermediate planetary systems, regardless of the planet mass, will be significantly detected in the near future.

  13. Long-range atmospheric transport of PAHs, PCBs and PBDEs to the central and eastern Mediterranean and changes of PCB and PBDE congener patterns in summer 2010

    Science.gov (United States)

    Mulder, Marie D.; Heil, Angelika; Kukučka, Petr; Kuta, Jan; Přibylová, Petra; Prokeš, Roman; Lammel, Gerhard

    2015-06-01

    The central and eastern Mediterranean is a receptor area for persistent organic pollutants (POPs) emitted in western, central and eastern Europe, particularly during summer. Atmospheric concentrations of PCBs, DDXs, PBDEs, penta- and hexachlorobenzene were measured during a ship-borne survey in the summer of 2010. The concentration of PCBs (sum of 7 congeners) was 3.61 (2.08-7.72) pg m-3, of which 6.7% was associated with the particulate phase. The mean concentration of DDT isomers and their metabolites, DDE and DDD, was 2.60 (0.46-7.60) pg m-3 (particulate mass fraction θ = 0.097), of penta- and hexachlorobenzene 0.22 (air masses studied had been transported mostly across central Europe, some crossing western Europe. The observed changes of PCB congener patterns along transport routes are in agreement with the perception that the reaction with the OH radical is dominating PCB atmospheric lifetime, and indicate an overestimation of the second order gas-phase reaction rate coefficient of PCB153 with OH by structure-activity relationship.

  14. Microbial infection and antibiotic patterns among intensive care unit patients in a tertiary hospital in Central Nepal

    Directory of Open Access Journals (Sweden)

    RK Sanjana

    2013-09-01

    Full Text Available Aims The present study is a fundamental effort to evaluate the bacteriological and antibiotic patterns in the Intensive Care Unit (ICU setting in a tertiary care hospital. This study was carried out to guide the clinician in choosing the appropriate antibiotics and to prevent emergence of multidrug resistance bacteria. Materials and Methods Between March 2009 to Feb 2012, the samples from various ICUs that were submitted to the microbiology laboratory for culture and sensitivity were included in this study. All the organisms were identified morphologically and biochemically by standard laboratory procedure and antibiotic susceptibility pattern was determined by disc diffusion methods. Result Of 3,780 specimens, 2,312 (61.1% isolates were recovered. Single organisms were isolated from 1,746 (75.5% samples while the remaining 566 (24.4% had two or more organisms isolated. Pseudomonas aeruginosa was the most common isolate 819 (35.4%, followed by Klebsiella pneumoniae 637 (27.5%. Antibiotics sensitivity of Pseudomonas aeruginosa showed that almost all isolates were resistant to cephalexin (97.8% and ciprofloxacin (80.3%. However (95.8% of the isolates were sensitive to tobramycin, (92.0% to meropenem & (74.80 % to amikacin. Conclusion It is concluded that Pseudomonas aeruginosa is the predominate pathogen isolated from ICUs of this Hospital. Most of the frequently isolated pathogens are resistant to cephalosporins and quinolone antibiotics as compared to aminoglycosides and carbapenem. Regular surveillance of antibiotic susceptibility pattern is very important for setting a guideline to the clinician in choosing an appropriate therapy of infected patients of ICUs. Journal of College of Medical Sciences-Nepal, 2012, Vol-8, No-3, 1-8 DOI: http://dx.doi.org/10.3126/jcmsn.v8i3.8678

  15. Next generation sequencing (NGS database for tandem repeats with multiple pattern 2°-shaft multicore string matching

    Directory of Open Access Journals (Sweden)

    Chinta Someswara Rao

    2016-03-01

    Full Text Available Next generation sequencing (NGS technologies have been rapidly applied in biomedical and biological research in recent years. To provide the comprehensive NGS resource for the research, in this paper , we have considered 10 loci/codi/repeats TAGA, TCAT, GAAT, AGAT, AGAA, GATA, TATC, CTTT, TCTG and TCTA. Then we developed the NGS Tandem Repeat Database (TandemRepeatDB for all the chromosomes of Homo sapiens, Callithrix jacchus, Chlorocebus sabaeus, Gorilla gorilla, Macaca fascicularis, Macaca mulatta, Nomascus leucogenys, Pan troglodytes, Papio anubis and Pongo abelii genome data sets for all those locis. We find the successive occurence frequency for all the above 10 SSR (simple sequence repeats in the above genome data sets on a chromosome-by-chromosome basis with multiple pattern 2° shaft multicore string matching.

  16. Next generation sequencing (NGS) database for tandem repeats with multiple pattern 2°-shaft multicore string matching.

    Science.gov (United States)

    Someswara Rao, Chinta; Raju, S Viswanadha

    2016-03-01

    Next generation sequencing (NGS) technologies have been rapidly applied in biomedical and biological research in recent years. To provide the comprehensive NGS resource for the research, in this paper , we have considered 10 loci/codi/repeats TAGA, TCAT, GAAT, AGAT, AGAA, GATA, TATC, CTTT, TCTG and TCTA. Then we developed the NGS Tandem Repeat Database (TandemRepeatDB) for all the chromosomes of Homo sapiens, Callithrix jacchus, Chlorocebus sabaeus, Gorilla gorilla, Macaca fascicularis, Macaca mulatta, Nomascus leucogenys, Pan troglodytes, Papio anubis and Pongo abelii genome data sets for all those locis. We find the successive occurence frequency for all the above 10 SSR (simple sequence repeats) in the above genome data sets on a chromosome-by-chromosome basis with multiple pattern 2° shaft multicore string matching. PMID:26981434

  17. Development of the automatic test pattern generation for NPP digital electronic circuits using the degree of freedom concept

    International Nuclear Information System (INIS)

    In this paper, an improved algorithm for automatic test pattern generation (ATG) for nuclear power plant digital electronic circuits--the combinational type of logic circuits is presented. For accelerating and improving the ATG process for combinational circuits the presented ATG algorithm has the new concept--the degree of freedom (DF). The DF, directly computed from the system descriptions such as types of gates and their interconnections, is the criterion to decide which among several alternate lines' logic values required along each path promises to be the most effective in order to accelerate and improve the ATG process. Based on the DF the proposed ATG algorithm is implemented in the automatic fault diagnosis system (AFDS) which incorporates the advanced fault diagnosis method of artificial intelligence technique, it is shown that the AFDS using the ATG algorithm makes Universal Card (UV Card) testing much faster than the present testing practice or by using exhaustive testing sets

  18. Environmental controls on spatial patterns in the long-term persistence of giant kelp in central California

    Science.gov (United States)

    Young, Mary Alida; Cavanaugh, Kyle C.; Bell, Tom W.; Raimondi, Peter T.; Edwards, Christopher A.; Drake, Patrick T.; Erikson, Li H.; Storlazzi, Curt

    2016-01-01

    As marine management is moving towards the practice of protecting static areas, it is 44 important to make sure protected areas capture and protect persistent populations. Rocky reefs in 45 many temperate areas worldwide serve as habitat for canopy forming macroalgae and these 46 structure forming species of kelps (order Laminariales) often serve as important habitat for a great 47 diversity of species. Macrocystis pyrifera is the most common canopy forming kelp species found 48 along the coast of California but the distribution and abundance of M. pyrifera varies in space and 49 time. The purpose of this study is to determine what environmental parameters are correlated with 50 the spatial and temporal persistence of M. pyrifera along the central coast of California and how 51 well those environmental parameters can be used to predict areas where M. pyrifera is more likely 52 to persist. Nine environmental variables considered in this study included depth of the seafloor, 53 structure of the rocky reef, proportion of rocky reef, size of kelp patch, biomass of kelp within a 54 patch, distance from the edge of a kelp patch, sea surface temperature, wave orbital velocities, and 55 population connectivity of individual kelp patches. Using a generalized linear mixed effects model 56 (GLMM), the persistence of M. pyrifera was significantly associated with seven of the nine 57 variables considered: depth, complexity of the rocky reef, proportion of rock, patch biomass, 58 distance from the edge of a patch, population connectivity, and wave-orbital velocities. These 59 seven environmental variables were then used to predict the persistence of kelp across the central 60 coast and these predictions were compared to a reserved dataset of M. pyrifera persistence, which 61 was not used in the creation of the GLMM. The environmental variables were shown to accurately 62 predict the persistence of M. pyrifera within the central coast of California (r = 0.71, P<0.001). 63 Because

  19. NON-NEUTRALIZED ELECTRIC CURRENT PATTERNS IN SOLAR ACTIVE REGIONS: ORIGIN OF THE SHEAR-GENERATING LORENTZ FORCE

    Energy Technology Data Exchange (ETDEWEB)

    Georgoulis, Manolis K. [Research Center for Astronomy and Applied Mathematics of the Academy of Athens, 4 Soranou Efesiou Street, Athens GR-11527 (Greece); Titov, Viacheslav S.; Mikic, Zoran [Predictive Science, Inc., 9990 Mesa Rim Road, San Diego, CA 92121 (United States)

    2012-12-10

    Using solar vector magnetograms of the highest available spatial resolution and signal-to-noise ratio, we perform a detailed study of electric current patterns in two solar active regions (ARs): a flaring/eruptive and a flare-quiet one. We aim to determine whether ARs inject non-neutralized (net) electric currents in the solar atmosphere, responding to a debate initiated nearly two decades ago that remains inconclusive. We find that well-formed, intense magnetic polarity inversion lines (PILs) within ARs are the only photospheric magnetic structures that support significant net current. More intense PILs seem to imply stronger non-neutralized current patterns per polarity. This finding revises previous works that claim frequent injections of intense non-neutralized currents by most ARs appearing in the solar disk but also works that altogether rule out injection of non-neutralized currents. In agreement with previous studies, we also find that magnetically isolated ARs remain globally current-balanced. In addition, we confirm and quantify the preference of a given magnetic polarity to follow a given sense of electric currents, indicating a dominant sense of twist in ARs. This coherence effect is more pronounced in more compact ARs with stronger PILs and must be of sub-photospheric origin. Our results yield a natural explanation of the Lorentz force, invariably generating velocity and magnetic shear along strong PILs, thus setting a physical context for the observed pre-eruption evolution in solar ARs.

  20. Dengue virus in sub-tropical northern and central Viet Nam: population immunity and climate shape patterns of viral invasion and maintenance.

    Directory of Open Access Journals (Sweden)

    Maia A Rabaa

    Full Text Available Dengue virus transmission occurs in both epidemic and endemic cycles across tropical and sub-tropical regions of the world. Incidence is particularly high in much of Southeast Asia, where hyperendemic transmission plagues both urban and rural populations. However, endemicity has not been established in some areas with climates that may not support year-round viral transmission. An understanding of how dengue viruses (DENV enter these environments and whether the viruses persist in inapparent local transmission cycles is central to understanding how dengue emerges in areas at the margins of endemic transmission. Dengue is highly endemic in tropical southern Vietnam, while increasingly large seasonal epidemics have occurred in northern Viet Nam over the last decade. We have investigated the spread of DENV-1 throughout Vietnam to determine the routes by which the virus enters northern and central regions of the country. Phylogeographic analysis of 1,765 envelope (E gene sequences from Southeast Asia revealed frequent movement of DENV between neighboring human populations and strong local clustering of viral lineages. Long-distance migration of DENV between human population centers also occurred regularly and on short time-scales, indicating human-mediated viral invasion into northern Vietnam. Human populations in southern Vietnam were found to be the primary source of DENV circulating throughout the country, while central and northern Vietnam acted as sink populations, likely due to reduced connectedness to other populations in the case of the central regions and to the influence of temperature variability on DENV replication and vector survival and competence in the north. Finally, phylogeographic analyses suggested that viral movement follows a gravity model and indicates that population immunity and physical and economic connections between populations may play important roles in shaping patterns of DENV transmission.

  1. Dengue virus in sub-tropical northern and central Viet Nam: population immunity and climate shape patterns of viral invasion and maintenance.

    Science.gov (United States)

    Rabaa, Maia A; Simmons, Cameron P; Fox, Annette; Le, Mai Quynh; Nguyen, Thuy Thi Thu; Le, Hai Yen; Gibbons, Robert V; Nguyen, Xuyen Thanh; Holmes, Edward C; Aaskov, John G

    2013-01-01

    Dengue virus transmission occurs in both epidemic and endemic cycles across tropical and sub-tropical regions of the world. Incidence is particularly high in much of Southeast Asia, where hyperendemic transmission plagues both urban and rural populations. However, endemicity has not been established in some areas with climates that may not support year-round viral transmission. An understanding of how dengue viruses (DENV) enter these environments and whether the viruses persist in inapparent local transmission cycles is central to understanding how dengue emerges in areas at the margins of endemic transmission. Dengue is highly endemic in tropical southern Vietnam, while increasingly large seasonal epidemics have occurred in northern Viet Nam over the last decade. We have investigated the spread of DENV-1 throughout Vietnam to determine the routes by which the virus enters northern and central regions of the country. Phylogeographic analysis of 1,765 envelope (E) gene sequences from Southeast Asia revealed frequent movement of DENV between neighboring human populations and strong local clustering of viral lineages. Long-distance migration of DENV between human population centers also occurred regularly and on short time-scales, indicating human-mediated viral invasion into northern Vietnam. Human populations in southern Vietnam were found to be the primary source of DENV circulating throughout the country, while central and northern Vietnam acted as sink populations, likely due to reduced connectedness to other populations in the case of the central regions and to the influence of temperature variability on DENV replication and vector survival and competence in the north. Finally, phylogeographic analyses suggested that viral movement follows a gravity model and indicates that population immunity and physical and economic connections between populations may play important roles in shaping patterns of DENV transmission. PMID:24340118

  2. Pareto optimality between width of central lobe and peak sidelobe intensity in the far-field pattern of lossless phase-only filters for enhancement of transverse resolution.

    Science.gov (United States)

    Mukhopadhyay, Somparna; Hazra, Lakshminarayan

    2015-11-01

    Resolution capability of an optical imaging system can be enhanced by reducing the width of the central lobe of the point spread function. Attempts to achieve the same by pupil plane filtering give rise to a concomitant increase in sidelobe intensity. The mutual exclusivity between these two objectives may be considered as a multiobjective optimization problem that does not have a unique solution; rather, a class of trade-off solutions called Pareto optimal solutions may be generated. Pareto fronts in the synthesis of lossless phase-only pupil plane filters to achieve superresolution with prespecified lower limits for the Strehl ratio are explored by using the particle swarm optimization technique. PMID:26560575

  3. Contrasting Holocene environmental histories may explain patterns of species richness and rarity in a Central European landscape

    Science.gov (United States)

    Hájek, Michal; Dudová, Lydie; Hájková, Petra; Roleček, Jan; Moutelíková, Jitka; Jamrichová, Eva; Horsák, Michal

    2016-02-01

    The south-western part of the White Carpathians (Czech Republic, Slovakia) is known for its exceptional grassland diversity and occurrence of many species with disjunct distribution patterns, including isolated populations of continental forest-steppe species. The north-eastern part of the mountain range lacks many of these species and has clearly lower maxima of grassland species richness. While climatic and edaphic conditions of both regions largely overlap, their specific environmental history has been hypothesized to explain the exceptional richness in the south-western part. We explored an entire-Holocene record (9650 BC onwards), the first one from the north-eastern part, to find out whether differences in history may explain regional patterns of species rarity and richness. We analysed pollen, macrofossils and molluscs and dated the sequence with 13 radiocarbon dates. We further reconstructed past human activities using available archaeological evidence. Based on this analysis, the Early-Holocene landscape was reconstructed as semi-open with broad-leaved trees (elm and lime) appearing already around 9500 BC. Lime reached a relative abundance of as much as 60% around 8700 BC. All analysed proxies support the existence of dense lime-dominated woodland during the forest optimum starting after climate moistening around 6800 BC, some 2200 years before the first signs of slight forest opening in the Late Neolithic. During the Bronze and Iron Ages, human pressure increased, which led to a decrease in lime and an increase in oak, hornbeam, grasses and grassland snails; nevertheless, forests still dominated the landscape and beech spread when human impact temporarily decreased. Colonisation after AD 1350 created the modern grassland-rich landscape. All available evidence confirmed an early post-Glacial expansion of broad-leaved trees, supporting the hypothesis on their glacial refugia in the Carpathians, as well as presence of closed-canopy forest well before the

  4. Investigation of Vortex Clouds and Droplet Sizes in Heated Water Spray Patterns Generated by Axisymmetric Full Cone Nozzles

    Directory of Open Access Journals (Sweden)

    M. Y. Naz

    2013-01-01

    Full Text Available The hot water sprays are an important part of many industrial processes, where the detailed knowledge of physical phenomena involved in jet transportation, interaction, secondary breakup, evaporation, and coalescence of droplets is important to reach more efficient processes. The objective of the work was to study the water spray jet breakup dynamics, vortex cloud formation, and droplet size distribution under varying temperature and load pressure. Using a high speed camera, the spray patterns generated by axisymmetric full cone nozzles were visualized as a function water temperature and load pressure. The image analysis confirmed that the spray cone angle and width do not vary significantly with increasing Reynolds and Weber numbers at early injection phases leading to increased macroscopic spray propagation. The formation and decay of semitorus like vortex clouds were also noticed in spray structures generated at near water boiling point temperature. For the nozzle with smallest orifice diameter (1.19 mm, these vortex clouds were very clear at 90°C heating temperature and 1 bar water load pressure. In addition, the sauter mean diameter (SMD of the spray droplets was also measured by using Phase Doppler Anemometry (PDA at different locations downstream of the nozzle exit. It was noticed that SMD varies slightly w.r.t. position when measured at room temperature whereas at higher temperature values, it became almost constant at distance of 55 mm downstream of the nozzle exit.

  5. Investigation of vortex clouds and droplet sizes in heated water spray patterns generated by axisymmetric full cone nozzles.

    Science.gov (United States)

    Naz, M Y; Sulaiman, S A; Ariwahjoedi, B; Ku Shaari, Ku Zilati

    2013-01-01

    The hot water sprays are an important part of many industrial processes, where the detailed knowledge of physical phenomena involved in jet transportation, interaction, secondary breakup, evaporation, and coalescence of droplets is important to reach more efficient processes. The objective of the work was to study the water spray jet breakup dynamics, vortex cloud formation, and droplet size distribution under varying temperature and load pressure. Using a high speed camera, the spray patterns generated by axisymmetric full cone nozzles were visualized as a function water temperature and load pressure. The image analysis confirmed that the spray cone angle and width do not vary significantly with increasing Reynolds and Weber numbers at early injection phases leading to increased macroscopic spray propagation. The formation and decay of semitorus like vortex clouds were also noticed in spray structures generated at near water boiling point temperature. For the nozzle with smallest orifice diameter (1.19 mm), these vortex clouds were very clear at 90°C heating temperature and 1 bar water load pressure. In addition, the sauter mean diameter (SMD) of the spray droplets was also measured by using Phase Doppler Anemometry (PDA) at different locations downstream of the nozzle exit. It was noticed that SMD varies slightly w.r.t. position when measured at room temperature whereas at higher temperature values, it became almost constant at distance of 55 mm downstream of the nozzle exit. PMID:24307881

  6. Twenty Years of Elfin Enumeration: Abundance Patterns of Five Species of Callophrys (Lycaenidae) in Central Wisconsin, USA

    Science.gov (United States)

    Swengel, Ann B.; Swengel, Scott R.

    2014-01-01

    We recorded five species of elfins (Callophrys) during annual spring surveys targeting frosted elfin C. irus (state-listed as threatened) in 19 pine-oak barrens in central Wisconsin USA during 1994–2013. At the northwest end of its range here, C. irus co-varied with spring temperature, but declined significantly over time (eight sites verified extant of originally 17). Two other specialists increased significantly. The northern specialist, hoary elfin C. polios (nine sites), correlated positively with the previous year’s growing season precipitation. The southern specialist, Henry’s elfin C. henrici (11 sites), co-varied with winter precipitation and spring temperature and dryness. The two resident generalists had stable trends. For all species, the first observed date per year became earlier over time and varied more than the last observed date. Thus, flight period span increased with earlier first observed dates. Elfin abundance increased significantly with earlier first observed dates in the current and/or prior year. Three species (C. irus, C. henrici, a generalist) had more positive population trends in reserves than non-reserves. This suggests that C. irus declines correspond to habitat conditions. Thus, monitoring programs and habitat management specifically for C. irus appear necessary to obtain a long-term stable trend for this species in Wisconsin. PMID:26462687

  7. Twenty Years of Elfin Enumeration: Abundance Patterns of Five Species of Callophrys (Lycaenidae in Central Wisconsin, USA

    Directory of Open Access Journals (Sweden)

    Ann B. Swengel

    2014-04-01

    Full Text Available We recorded five species of elfins (Callophrys during annual spring surveys targeting frosted elfin C. irus (state-listed as threatened in 19 pine-oak barrens in central Wisconsin USA during 1994–2013. At the northwest end of its range here, C. irus co-varied with spring temperature, but declined significantly over time (eight sites verified extant of originally 17. Two other specialists increased significantly. The northern specialist, hoary elfin C. polios (nine sites, correlated positively with the previous year’s growing season precipitation. The southern specialist, Henry’s elfin C. henrici (11 sites, co-varied with winter precipitation and spring temperature and dryness. The two resident generalists had stable trends. For all species, the first observed date per year became earlier over time and varied more than the last observed date. Thus, flight period span increased with earlier first observed dates. Elfin abundance increased significantly with earlier first observed dates in the current and/or prior year. Three species (C. irus, C. henrici, a generalist had more positive population trends in reserves than non-reserves. This suggests that C. irus declines correspond to habitat conditions. Thus, monitoring programs and habitat management specifically for C. irus appear necessary to obtain a long-term stable trend for this species in Wisconsin.

  8. Development and justification of a scheme for commercial supply of radiopharmpreparation 99mTc using centralized Zr-Mo gel-generator

    International Nuclear Information System (INIS)

    Zr-Mo gel-generator 99mTc on the basis of activated 99Mo is used in modern medical diagnostics as a convenient, safe and reliable local source of 99mTc production in the form of sodium pertechnetate. The methodology and technological process of the wasteless reactor gel-technology of radiopharmpreparation (RPhP) 99mTc production with the use of centralized Zr-Mo gel-generator has been developed in the Institute of Power Engineering Problems, National Academy of Sciences of Belarus in co-operation with Scientific Research institute of Oncology and Medical Radiology of Ministry of Health of the Republic of Belarus. As a result of performed clinical tests the Ministry of Health had approved the clinical application of RPhP 99mTc produced according to this technology. Zr-Mo gel-generator at full load of 150-370 GBq of 99Mo can provide with 99mTc solution such a region as the Republic of Belarus and export the preparation. An optimization of initial irradiation of MoO3 target in a nuclear reactor as well as conditions of the gel-generator operation is important for definition of the price of produced 99mTc. The technological process of delivery of sodium pertechnetate (99mTc) produced according to Zr-Mo gel-technology at centralized generator has been modeled where the main technological steps were considered, such as irradiation of target in reactor, loading into container, transport to the centralized generator, charging of the generator, gel preparation, operation of the centralized generator, and delivery of final product to the hospitals. In developed mathematical model with two-component presentation of 98Mo activation reaction velocity on neutrons the activity value is presented in the form of two multipliers: the first multiplier describes the dependence on neutron thermal flux density, spectrum hardness, enrichment of 98Mo target, target geometry; the second multiplier sets time dependence. On the basis of this model the different irradiation conditions and

  9. Patterns in abundance and diversity of faecally dispersed parasites of tiger in Tadoba National Park, central India

    Directory of Open Access Journals (Sweden)

    Jog Maithili M

    2002-05-01

    Full Text Available Abstract Background Importance of parasites in ecological and evolutionary interactions is being increasingly recognized. However, ecological data on parasites of important host species is still scanty. We analyze the patterns seen in the faecal parasites of tigers in the Tadoba National Park, India, and speculate on the factors and processes shaping the parasite community and the possible implications for tiger ecology. Results The prevalence and intensities were high and the parasite community was dominated by indirect life cycle parasites. Across all genera of parasites variance scaled with the square of the mean and there was a significant positive correlation between prevalence and abundance. There was no significant association between different types of parasites. Conclusions The 70 samples analyzed formed 14 distinct clusters. If we assume each of the clusters to represent individual tigers that were sampled repeatedly and that resident tigers are more likely to be sampled repeatedly, the presumed transient tigers had significantly greater parasite loads than the presumed resident ones.

  10. Demographic patterns and trends in Central Ghana: baseline indicators from the Kintampo Health and Demographic Surveillance System

    Directory of Open Access Journals (Sweden)

    Seth Owusu-Agyei

    2012-12-01

    Full Text Available Background: The dearth of health and demographic data in sub-Saharan Africa from vital registration systems and its impact on effective planning for health and socio-economic development is widely documented. Health and Demographic Surveillance Systems have the capacity to address the dearth of quality data for policy making in resource-poor settings. Objective: This article demonstrates the utility of the Kintampo Health and Demographic Surveillance System (KHDSS by showing the patterns and trends of population change from 2005 to 2009 in the Kintampo North Municipality and Kintampo South districts of Ghana through data obtained from the KHDSS biannual update rounds. Design: Basic demographic rates for fertility, mortality, and migration were computed by year. School enrolment was computed as a percentage in school by age and sex for 6–18 year-olds. Socio-economic status was derived by use of Principal Components Analysis on household assets. Results: Over the period, an earlier fertility decline was reversed in 2009; mortality declined slightly for all age-groups, and a significant share of working-age population was lost through out-migration. Large minorities of children of school-going age are not in school. Socio-economic factors are shown to be important determinants of fertility and mortality. Conclusion : Strengthening the capacity of HDSSs could offer added value to evidence-driven policymaking at local level.

  11. The expression pattern of Adam10 in the central nervous system of adult mice: Detection by in situ hybridization combined with immunohistochemistry staining.

    Science.gov (United States)

    Guo, Zhi-Bao; Su, Ying-Ying; Wang, Yi-Hui; Wang, Wei; Guo, Da-Zhi

    2016-09-01

    ADAM10 (a disintegrin and metalloprotease 10) is a member of the ADAMs family, which is key in the development of the nervous system, by regulating proliferation, migration, differentiation and survival of various cells, including axonal growth and myelination. Previous studies have investigated the embryonic or postnatal expression of ADAM10, however, detailed information regarding its cellular distribution in the adult stage, to the best of our knowledge, is not available. The present study investigated the expression pattern of the ADAM10 gene in the adult mouse central nervous system (CNS) using an ADAM10 complementary RNA probe for in situ hybridization (ISH). Immunohistochemical staining was used to identify the type of the ISH staining‑positive cells with neuron‑ or astrocyte‑specific antibodies. The results of the current study demonstrated that the ADAM10 gene was predominantly expressed in the neurons of the cerebral cortex, hippocampus, thalamus and cerebellar granular cells in adult mouse CNS. PMID:27431484

  12. The invasive ctenophore Mnemiopsis leidyi in the central Baltic Sea: seasonal phenology and hydrographic influence on spatio-temporal distribution patterns

    DEFF Research Database (Denmark)

    Schaber, M.; Haslob, H.; Huwer, Bastian;

    2011-01-01

    In the Western Baltic, the invasive ctenophore Mnemiopsis leidyi was recorded for the first time in autumn 2006. An eastward propagation of the ctenophore into the central Baltic, and thus into important spawning grounds of major Baltic fish stocks, was observed in 2007. The focus of the present...... study was to investigate the seasonal phenology of this introduced species and whether it is able to form a self-sustaining population in this area. Therefore, the variability of temporal and spatial distribution of M. leidyi in the Bornholm Basin was analyzed over the first 4 years following...... the invasion and related to ambient hydrographic parameters. Results show a clear seasonal pattern. In contrast to the majority of other native and exotic habitats, the seasonal phenology showed highest abundances in spring and autumn months and only sporadic or even no appearance during summer. Vertical...

  13. Three-dimensional cooling pattern of a granitic pluton I. The study of exsolution sub-solidus reactions in the Toki granite, Central Japan

    International Nuclear Information System (INIS)

    This paper presents the results of petrographical studies carried out to examine the development and variation of sub-solidus reactions occurring in the Toki granite, Central Japan. The results reveal the three-dimensional cooling pattern of this zoned pluton. Samples collected from 19 boreholes in the Toki granite indicate a spatial variation in the extent of sub-solidus reactions. Exsolution coarsening produced microperthite textures with albite-rich lamellae in this pluton, whereas deuteric coarsening resulted in patchperthite with albite-rich patches. The width and spacing of the albite-rich lamella in microperthite increase systematically and prominently with elevation in the pluton. This indicates that the Toki granite effectively cooled from the roof during the exsolution coarsening stage. Measurements obtained using the hornblende-plagioclase and ternary feldspar thermometers indicate that volume diffusion took place in the temperature range 780-690°C; this diffusion was associated with exsolution coarsening. (author)

  14. Synchronous degassing patterns of the neighbouring volcanoes Llaima and Villarrica in south-central Chile: the influence of tidal forces

    Science.gov (United States)

    Bredemeyer, Stefan; Hansteen, Thor H.

    2014-10-01

    The neighbouring volcanoes Villarrica and Llaima are two of the most active volcanoes in Chile and both currently degas continuously. We present a semi-continuous time series of SO2 fluxes for Villarrica and Llaima volcanoes. The time series was obtained using five scanning Mini-Differential Optical Absorption Spectrometers (Mini-DOAS, UV spectrometers) over 6 months (13 February to 31 July 2010) and is based on 6,829 scans for Villarrica and 7,165 scans for Llaima. Statistical analyses of the SO2 flux time series reveal a periodicity of degassing maxima about every 7 days, and further a conspicuous synchronicity of the degassing maxima and minima between the two volcanoes. Intra-day variations in SO2 fluxes also show a striking correlation between Villarrica and Llaima. All these patterns correlate well with the trend of the modelled solid Earth tide curves, where the 7-day degassing maxima correspond with both the fortnightly tidal maxima and minima. The intra-day degassing peaks mostly correlate well with the periods of maximum deformation rates during the diurnal tidal cycle, and further with semidiurnal minima in atmospheric pressure, a phenomenon we refer to as "the tidal pump". As there is little time lag between the tidal action and the changes in degassing rates, we infer that degassing at both volcanoes is controlled by conduit convection, involving physical separation between gas and magma at comparatively shallow levels. Variations in daily degassing rates were up to a factor of ca. 12 and 10 for Villarrica and Llaima, respectively, without any noticeable changes in the periodicity. We thus suggest that the described cyclic variations must be taken into account for all comparable volcanoes when using gas monitoring as a tool for volcanic hazard mitigation.

  15. Measuring citalopram in blood and central nervous system: revealing a distribution pattern that differs from other antidepressants.

    Science.gov (United States)

    Paulzen, Michael; Lammertz, Sarah E; Gründer, Gerhard; Veselinovic, Tanja; Hiemke, Christoph; Tauber, Simone C

    2016-05-01

    The aim of this study was to measure blood and cerebrospinal fluid concentrations of citalopram and its weakly active N-demethylated metabolite desmethylcitalopram to account for the distribution between the two compartments. The findings are discussed in the context with own preceding studies on the distribution pattern of different antidepressants. Concentrations of citalopram were measured in blood serum and cerebrospinal fluid of 18 patients treated with daily doses of 10-40 mg. Daily doses were correlated with serum and cerebrospinal fluid concentrations, and serum concentrations were correlated with concentrations in cerebrospinal fluid. Serum concentrations of citalopram and desmethylcitalopram showed no significant correlation to the daily dose, r=0.164, P=0.515, and r=0.174, P=0.505, respectively, whereas citalopram concentrations in serum and cerebrospinal fluid were highly correlated (r=0.763, Pcitalopram (total=bound+unbound concentration) varied between 0.14 and 0.86 (mean 0.35, SD 0.16). By correcting the mean cerebrospinal fluid/serum ratio for 80% plasma protein binding, cerebrospinal fluid concentrations of citalopram were on average 77% higher than the calculated unbound serum concentration with a ratio of 1.77 (SD 0.81, range 0.68-4.29). Findings indicate a very good ability of citalopram to cross the blood-brain and cerebrospinal fluid barrier. High concentrations of citalopram in the cerebrospinal fluid are indicative of active transport of citalopram into or missing active transport out of the cerebrospinal fluid. The results suggest a high ability of citalopram to enter the brain with sufficiently high drug concentrations at the target sites within the brain, contributing toward clinical efficacy. PMID:26650488

  16. Sources and the flux pattern of dissolved carbon in rivers of the Yenisey basin draining the Central Siberian Plateau

    International Nuclear Information System (INIS)

    Frequent measurements of dissolved organic (DOC) and inorganic (DIC) carbon concentrations in rivers during snowmelt, the entire ice-free season, and winter were made in five large watersheds (15 000–174 000 km2) of the Central Siberian Plateau (Yenisey River basin). These differ in the degree of continuous permafrost coverage, mean annual air temperature, and the proportion of tundra and forest vegetation. With an annual DOC export from the catchment areas of 2.8–4.7 gC m−2 as compared to an annual DIC export of 1.0–2.8 gC m−2, DOC was the dominant component of terrigenous C released to rivers. There was strong temporal variation in the discharge of DOC and DIC. Like for other rivers of the pan-arctic and boreal zones, snowmelt dominated annual fluxes, being 55–71% for water runoff, 64–82% for DOC and 37–41% for DIC. Likewise, DOC and DIC exhibited also a strong spatial variation in C fluxes, with both dissolved C species decreasing from south to north. The rivers of the southern part of the plateau had the largest flow-weighted DOC concentrations among those previously reported for Siberian rivers, but the smallest flow-weighted DIC concentrations. In the study area, DOC and DIC fluxes were negatively correlated with the distribution of continuous permafrost and positively correlated with mean annual air temperature. A synthesis of literature data shows similar trends from west to east, with an eastward decrease of dissolved C concentrations and an increased proportion of DOC in the total dissolved C flux. It appears that there are two contemporary limitations for river export of terrigenous C across Siberia: (1) low productivity of ecosystems with respect to potentially mobilizable organic C, slow weathering rates with concomitant small formation of bicarbonate, and/or wildfire disturbance limit the pools of organic and inorganic C that can be mobilized for transport in rivers (source-limited), and (2) mobilization of available pools of C is

  17. Aluminium Accumulation and Intra-Tree Distribution Patterns in Three Arbor aluminosa (Symplocos) Species from Central Sulawesi.

    Science.gov (United States)

    Schmitt, Marco; Boras, Sven; Tjoa, Aiyen; Watanabe, Toshihiro; Jansen, Steven

    2016-01-01

    Accumulation of Aluminium (Al) at concentrations far above 1,000 mg kg-1 in aboveground plant tissues of Arbor aluminosa (Symplocos) species is the main reason why traditional Indonesian weavers rely on their leaves and bark as a mordant for dyeing textile. Recently, Symplocos species have become a flagship species for the conservation efforts of weaving communities due to their traditionally non-sustainable sampling and increasing demand for Symplocos plant material. Here we investigated Symplocos odoratissima, S. ophirensis and S. ambangensis at three montane rainforest sites in Central Sulawesi to measure Al levels in different tissues and organs. The highest Al concentrations were found in old leaves (24,180 ± 7,236 mg·kg-1 dry weight, mean ± SD), while young leaves had significantly lower Al levels (20,708 ± 7,025 mg·kg-1). Al accumulation was also lower in bark and wood tissue of the trunk (17,231 ± 8,356 mg·kg-1 and 5,181 ± 2,032 mg·kg-1, respectively). Two Al excluding species (Syzigium sp. and Lithocarpus sp.) contained only high Al levels in their roots. Moreover, no difference was found in soil pH (4.7 ± 0.61) and nutrient (K, Ca, Fe, Mg) availability at different soil levels and within or outside the crown of Symplocos trees, except for the upper soil layer. Furthermore, a positive and significant correlation between Al and Ca concentrations was found at the whole plant level for Symplocos, and at the leaf level for S. ophirensis and S. ambangensis, suggesting a potential role of Ca in Al uptake and/or detoxification within the plant. Our results provide evidence for strong Al accumulation in Symplocos species and illustrate that both Al accumulation and exclusion represent two co-occurring strategies of montane rainforest plants for dealing with Al toxicity. Indonesian weavers should be encouraged to harvest old leaves, which have the most efficient mordant capacity due to high Al concentrations. PMID:26871698

  18. Aluminium Accumulation and Intra-Tree Distribution Patterns in Three Arbor aluminosa (Symplocos) Species from Central Sulawesi

    Science.gov (United States)

    Schmitt, Marco; Boras, Sven; Tjoa, Aiyen; Watanabe, Toshihiro; Jansen, Steven

    2016-01-01

    Accumulation of Aluminium (Al) at concentrations far above 1,000 mg kg-1 in aboveground plant tissues of Arbor aluminosa (Symplocos) species is the main reason why traditional Indonesian weavers rely on their leaves and bark as a mordant for dyeing textile. Recently, Symplocos species have become a flagship species for the conservation efforts of weaving communities due to their traditionally non-sustainable sampling and increasing demand for Symplocos plant material. Here we investigated Symplocos odoratissima, S. ophirensis and S. ambangensis at three montane rainforest sites in Central Sulawesi to measure Al levels in different tissues and organs. The highest Al concentrations were found in old leaves (24,180 ± 7,236 mg·kg-1 dry weight, mean ± SD), while young leaves had significantly lower Al levels (20,708 ± 7,025 mg·kg-1). Al accumulation was also lower in bark and wood tissue of the trunk (17,231 ± 8,356 mg·kg-1 and 5,181 ± 2,032 mg·kg-1, respectively). Two Al excluding species (Syzigium sp. and Lithocarpus sp.) contained only high Al levels in their roots. Moreover, no difference was found in soil pH (4.7 ± 0.61) and nutrient (K, Ca, Fe, Mg) availability at different soil levels and within or outside the crown of Symplocos trees, except for the upper soil layer. Furthermore, a positive and significant correlation between Al and Ca concentrations was found at the whole plant level for Symplocos, and at the leaf level for S. ophirensis and S. ambangensis, suggesting a potential role of Ca in Al uptake and/or detoxification within the plant. Our results provide evidence for strong Al accumulation in Symplocos species and illustrate that both Al accumulation and exclusion represent two co-occurring strategies of montane rainforest plants for dealing with Al toxicity. Indonesian weavers should be encouraged to harvest old leaves, which have the most efficient mordant capacity due to high Al concentrations. PMID:26871698

  19. Automated pattern recognition to support geological mapping and exploration target generation - A case study from southern Namibia

    Science.gov (United States)

    Eberle, Detlef; Hutchins, David; Das, Sonali; Majumdar, Anandamayee; Paasche, Hendrik

    2015-06-01

    to the result obtained from unsupervised fuzzy clustering. Furthermore, a comparison of the aposterior probability of class assignment with the trustworthiness values provided by fuzzy clustering also indicates only slight differences. These observed differences can be explained by the exponential class probability term which tends to deliver either fairly high or low probability values. The methodology and results presented here demonstrate that automated objective pattern recognition can essentially contribute to geological mapping of large study areas and mineral exploration target generation. This methodology is considered well suited to a number of African countries whose large territories have recently been covered by high resolution airborne geophysical data, but where existing geological mapping is poor, incomplete or outdated.

  20. Generating Within-Plant Spatial Distributions of an Insect Herbivore Based on Aggregation Patterns and Per-Node Infestation Probabilities.

    Science.gov (United States)

    Rincon, Diego F; Hoy, Casey W; Cañas, Luis A

    2015-04-01

    Most predator-prey models extrapolate functional responses from small-scale experiments assuming spatially uniform within-plant predator-prey interactions. However, some predators focus their search in certain plant regions, and herbivores tend to select leaves to balance their nutrient uptake and exposure to plant defenses. Individual-based models that account for heterogeneous within-plant predator-prey interactions can be used to scale-up functional responses, but they would require the generation of explicit prey spatial distributions within-plant architecture models. The silverleaf whitefly, Bemisia tabaci biotype B (Gennadius) (Hemiptera: Aleyrodidae), is a significant pest of tomato crops worldwide that exhibits highly aggregated populations at several spatial scales, including within the plant. As part of an analytical framework to understand predator-silverleaf whitefly interactions, the objective of this research was to develop an algorithm to generate explicit spatial counts of silverleaf whitefly nymphs within tomato plants. The algorithm requires the plant size and the number of silverleaf whitefly individuals to distribute as inputs, and includes models that describe infestation probabilities per leaf nodal position and the aggregation pattern of the silverleaf whitefly within tomato plants and leaves. The output is a simulated number of silverleaf whitefly individuals for each leaf and leaflet on one or more plants. Parameter estimation was performed using nymph counts per leaflet censused from 30 artificially infested tomato plants. Validation revealed a substantial agreement between algorithm outputs and independent data that included the distribution of counts of both eggs and nymphs. This algorithm can be used in simulation models that explore the effect of local heterogeneity on whitefly-predator dynamics. PMID:26313173

  1. A method to integrate patterned electrospun fibers with microfluidic systems to generate complex microenvironments for cell culture applications.

    Science.gov (United States)

    Wallin, Patric; Zandén, Carl; Carlberg, Björn; Hellström Erkenstam, Nina; Liu, Johan; Gold, Julie

    2012-06-01

    The properties of a cell's microenvironment are one of the main driving forces in cellular fate processes and phenotype expression invivo. The ability to create controlled cell microenvironments invitro becomes increasingly important for studying or controlling phenotype expression in tissue engineering and drug discovery applications. This includes the capability to modify material surface properties within well-defined liquid environments in cell culture systems. One successful approach to mimic extra cellular matrix is with porous electrospun polymer fiber scaffolds, while microfluidic networks have been shown to efficiently generate spatially and temporally defined liquid microenvironments. Here, a method to integrate electrospun fibers with microfluidic networks was developed in order to form complex cell microenvironments with the capability to vary relevant parameters. Spatially defined regions of electrospun fibers of both aligned and random orientation were patterned on glass substrates that were irreversibly bonded to microfluidic networks produced in poly-dimethyl-siloxane. Concentration gradients obtained in the fiber containing channels were characterized experimentally and compared with values obtained by computational fluid dynamic simulations. Velocity and shear stress profiles, as well as vortex formation, were calculated to evaluate the influence of fiber pads on fluidic properties. The suitability of the system to support cell attachment and growth was demonstrated with a fibroblast cell line. The potential of the platform was further verified by a functional investigation of neural stem cell alignment in response to orientation of electrospun fibers versus a microfluidic generated chemoattractant gradient of stromal cell-derived factor 1 alpha. The described method is a competitive strategy to create complex microenvironments invitro that allow detailed studies on the interplay of topography, substrate surface properties, and soluble

  2. The fractional patterns of polybrominated diphenyl ethers in the soil of the central Tibetan Plateau, China: The influence of soil components

    International Nuclear Information System (INIS)

    Sixteen soil samples were collected from the central Tibetan Plateau (CTP). The soil concentrations of polybrominated diphenyl ethers (PBDEs) in CTP were analyzed. The detected 42 congeners were divided into light, intermediate and heavy fractions. In addition to the various minerals, other soil properties were also characterized, including the content of soil organic carbon (SOC) and the particle size distribution. The clay content is positively related to the intermediate fraction of the PBDEs and negatively related to the light and heavy fractions. Similar correlations were observed for SOC and the fine-particle fraction (size 2) associated with a linear regression indicated that the clays were more highly correlated with the fractional pattern of the PBDEs than with the other properties, such as SOC and the fine-particle fraction. The values of r2 between clays and three fractions of PBDEs are 0.70, 0.69 and 0.58. Highlights: ► All data about soil and PBDEs were based on field data rather than experiments. ► The intermediate fraction of PBDEs increased with increases in the clay content. ► The clays were more strongly correlated with PBDEs fractional patterns than SOC. - Certain minerals, such as clays, have a greater impact on the adsorption of POPs than SOC in certain areas.

  3. A model of co-occurrence: segregation and aggregation patterns in the mycoflora of the crayfish Procambarus clarkii in Lake Trasimeno (central Italy

    Directory of Open Access Journals (Sweden)

    Antonia C. Elia

    2012-01-01

    Full Text Available Although attention on crayfish diseases has recently proliferated, the focus is mainly on a single host-parasite relationship rather than analyzing the entire mycoflora, probably due to the fact that (1 some diseases are occasional (pathogens of which are of difficult collection and (2 economic impact is more relevant in aquaculture (i.e., a controlled environment where only few parasites occur than in natural conditions. Contrary to this viewpoint, fungal ectoparasites assume a great importance since they are integral components in shaping community, ecosystem structure, and energy flow. Here we described the fungal species co-occurrence patterns (species segregation/ aggregation using null models comparing the occurrence frequencies of ectosymbiots through host individuals with those expected by chance. Non-indigenous crayfish species like Procambarus clarkii allow to observe phenomena of competitive exclusion (segregation or mutualism (aggregation amongst fungi. We analyzed the fungal species occurrence on 86 host crayfish monthly collected from June 2007 to June 2008 in the Lake Trasimeno (Central Italy. A total of 29 fungal taxa were detected. Taxa showed a particular fungal assemblage with a great species variation depending on sampling month and crayfish sex, size, and body region. In particular, fungal species showed different occurrence patterns in both richness and segregation/ aggregation. The fungal community shows a non-random structure not in all cases, with the majority of tests indicating segregation, not aggregation of ectosymbiontic species on hosts. The non-random patterns of fungal co-occurrence in some cases suggest that some temporally or spatially variable factors are responsible for the establishment of the mycoflora community assemblage. We also detected temporal differences in fungal co-occurrences patterns. Regarding seasonal samples, the same analyses showed a competitive structure only in the sub-communities found on

  4. Patterns of thyroid hormone receptor expression in zebrafish and generation of a novel model of resistance to thyroid hormone action.

    Science.gov (United States)

    Marelli, Federica; Carra, Silvia; Agostini, Maura; Cotelli, Franco; Peeters, Robin; Chatterjee, Krishna; Persani, Luca

    2016-03-15

    Resistance to thyroid hormone can be due to heterozygous, dominant negative (DN) THRA (RTHα) or THRB (RTHβ) mutations, but the underlying mechanisms are incompletely understood. Here, we delineate the spatiotemporal expression of TH receptors (TRs) in zebrafish and generated morphants expressing equivalent amounts of wild-type and DN TRαs (thraa_MOs) and TRβs (thrb_MOs) in vivo. Both morphants show severe developmental abnormalities. The phenotype of thraa_MOs includes brain and cardiac defects, but normal thyroid volume and tshba expression. A combined modification of dio2 and dio3 expression can explain the high T3/T4 ratio seen in thraa_MOs, as in RTHα. Thrb_MOs show abnormal eyes and otoliths, with a typical RTHβ pattern of thyroid axis. The coexpression of wild-type, but not mutant, human TRs can rescue the phenotype in both morphants. High T3 doses can partially revert the dominant negative action of mutant TRs in morphant fish. Therefore, our morphants recapitulate the RTHα and RTHβ key manifestations representing new models in which the functional consequences of human TR mutations can be rapidly and faithfully evaluated. PMID:26802880

  5. Erosividade e padrões hidrológicos de precipitação no Agreste Central pernambucano Erosivity and rainfall hydrological patterns in the Pernambuco Central 'Agreste'

    Directory of Open Access Journals (Sweden)

    Thais E. M. dos Santos

    2012-08-01

    Full Text Available A principal forma de erosão nas condições brasileiras é a causada pela energia cinética do impacto das gotas de chuva sobre a superfície do solo, desencadeando o processo de erosão hídrica. Desenvolveu-se o presente trabalho com o objetivo de avaliar o índice de erosividade (EI30 e caracterizar o padrão hidrológico das chuvas do Agreste Central pernambucano, considerando-se uma série de 29 anos de dados, ficando patente que o primeiro semestre do ano é caracterizado pela ocorrência de chuvas de elevado potencial erosivo. O valor do fator "R" da equação universal de perda de solo para a região estudada é de 2.779,79 MJ mm ha-1 h-1. O padrão de chuva de maior ocorrência é o avançado, seguido do intermediário e atrasado, com 46,57; 36,38 e 17,19% dos totais de chuvas erosivas analisados, respectivamente. Não foram encontradas correlações significativas entre erosividade, coeficiente de chuva e precipitação.The main form of erosion in Brazilian conditions is caused by the kinetic energy of the impact of raindrops on the soil surface, triggering the erosion process. The present study was conducted with the aim to evaluate the erosivity index (EI30, as well as to characterize the hydrological pattern of rainfall in the Pernambuco Central 'Agreste', considering a series of 29 years of data. It was found that the first half of the year is characterized by rain with high erosive potential. The value of the factor "R" in the Universal equation of soil loss for the studied region is 2,779.79 MJ mm ha-1 h-1. The rain pattern of higher occurrence is the advanced, followed by intermediate and delayed, with 46.57; 36.38 and 17.19% of total erosive rainfall analyzed, respectively. There were no significant correlations between erosivity, rainfall coefficient and precipitation.

  6. Development of the control assembly pattern and dynamic analysis of the generation IV large gas-cooled fast reactor (GFR)

    International Nuclear Information System (INIS)

    hydraulics analysis, the CEA code COPERNIC was used. This design work was followed by the study of an appropriate CA implementation scheme (number of CAs and corresponding positions within the core). Detailed neutronics studies revealed the existence of large CA interaction effects, called shadowing/anti-shadowing effects leading to an amplification/reduction of the CA worth. The interactions between the absorber pins within a CA, and between the CAs themselves, were investigated in detail, with the goal to optimize the CA efficiency, in terms of the absorber fraction and minimization of the associated heterogeneity effects. The proposed CA pattern consists of 54 absorber pins placed in a triangular lattice. Each absorber pin is a stainless-steel tube filled with highly enriched 10B boron carbide pellets. As a result of the detailed investigations, the absorber pin diameter could be chosen such as to minimize the pin-to-pin influence within the assembly. In particular, a central part of the CA was designed without any absorber pins (zone filled with stagnant helium). A final reduction of the heterogeneity effect (difference between homogeneous and heterogeneous treatments) to 13% was achieved through this feature. Of special importance, the neutronics investigations performed for the reference GFR core ('2004-Core'), especially those related to the CA interactions, have directly contributed to a new core design ('2007-Core'), with the height-to-diameter ratio having been increased to 0.6, compared to 0.3 for the reference core. During the third phase, detailed coupled, 3D neutron-kinetics (NK) and 1D thermal-hydraulics (TH) models were developed for the GFR core, the aim being to arrive at an in depth understanding of the 3D core behavior during CA driven transients, especially from the viewpoint of spatial effects. The coupled models were developed using the PARCS code for the 3D NK and the TRACE code for the 1D TH modeling. Particular attention was paid to have each

  7. Soil cover patterns and SOC dynamics impacts on the soil processes, land management and ecosystem services in Central Region of Russia

    Science.gov (United States)

    Vasenev, Ivan; Chernikov, Vladimir; Yashin, Ivan; Geraskin, Mikhail; Morev, Dmitriy

    2014-05-01

    In the Central Region of Russia (CRR) the soil cover patterns usually play the very important role in the soil forming and degradation processes (SFP & SDP) potential and current rates, soil organic carbon (SOC) dynamics and pools, greenhouse gases (GHG) emissions and soluble SOC fluxes that we need take into attention for better assessment of the natural and especially man-changed ecosystems' services and for best land-use practices development. Central Region of Russia is the biggest one in RF according to its population and role in the economy. CRR is characterized by high spatial variability of soil cover due to as original landscape heterogeneity as complicated history of land-use practices during last 700 years. Our long-term researches include the wide zonal-provincial set of representative ecosystems and soil cover patterns with different types and history of land-use (forest, meadow-steppe and agricultural ones) from middle-taiga to steppe zones with different level of continentality. The carried out more than 30-years region- and local-scale researches of representative natural and rural landscapes in Tver', Yaroslavl', Kaluga, Moscow, Vladimir, Saransk (Mordovia), Kursk, Orel, Tambov, Voronezh and Saratov oblasts give us the interregional multi-factorial matrix of elementary soil cover patterns (ESCP) with different soil forming and degradation processes rates and soil organic carbon dynamics due to regionally specific soil-geomorphologic features, environmental and dominated microclimate conditions, land-use current practices and history. The validation and ranging of the limiting factors of SFP and SDP develop¬ment, soil carbon dynamics and sequestration potential, ecosystem (agroecosystem) principal services, land functional qualities and agroecological state have been done for dominating and most dynamical components of ESCP regional-typological forms - with application of SOC structure analysis, regional and local GIS, soil spatial patterns detail

  8. Satellite-measured interannual variability of turbid river plumes off central-southern Chile: Spatial patterns and the influence of climate variability

    Science.gov (United States)

    Saldías, Gonzalo S.; Largier, John L.; Mendes, Renato; Pérez-Santos, Iván; Vargas, Cristian A.; Sobarzo, Marcus

    2016-08-01

    Ocean color imagery from MODIS (Moderate Resolution Imaging Spectroradiometer) onboard the Aqua platform is used to characterize the interannual variability of turbid river plumes off central-southern Chile. Emphasis is placed on the influence of climate fluctuations, namely El Niño Southern Oscillation (ENSO), the Pacific Decadal Oscillation (PDO), and the Antarctic Oscillation (AAO). Additional satellite data on wind, boat-based hydrographic profiles, and regional climate indices are used to identify the influence of climate variability on the generation of anomalous turbid river plumes. The evolution of salinity at a coastal station on the 90 m isobath between the Itata and Biobío Rivers shows a freshwater surface layer with salinity importance of long-term and high-resolution ocean color observations for studying the temporal evolution of river plumes.

  9. Techno-economic pre-feasibility study of wind and solar electricity generating systems for households in Central Finland

    OpenAIRE

    Alavi, Seyed Mehdi

    2014-01-01

    The objective of this work is to investigate the viability of a wind, PV or hybrid wind-PV system supplemented with battery storage for electricity production to meet the electricity consumption of a typical household apartment in Central Finland. The assessment criteria for the analysis were cost of energy and total net present cost of each system configuration. We selected the Hybrid Optimization Model for Electric Renewables (HOMER) software, RETScreen, and PVsyst in our analysis and final...

  10. Next generation of non-mammalian blood-brain barrier models to study parasitic infections of the central nervous system

    OpenAIRE

    Siddiqui, Ruqaiyyah; Edwards-Smallbone, James; Flynn, Robin; Khan, Naveed Ahmed

    2012-01-01

    Transmigration of neuropathogens across the blood-brain barrier is a key step in the development of central nervous system infections, making it a prime target for drug development. The ability of neuropathogens to traverse the blood-brain barrier continues to inspire researchers to understand the specific strategies and molecular mechanisms that allow them to enter the brain. The availability of models of the blood-brain barrier that closely mimic the situation in vivo offers unprecedented o...

  11. Central Asia in a Changing World: From a Peripheral Region to an Area of Policy Generation and Application. Actors, Policy and Security

    Directory of Open Access Journals (Sweden)

    Nora Sainz Gsell

    2005-10-01

    Full Text Available This work deals with Central Asia, beginning with an analysis of the characteristics of international insertion of the area as a whole and of the former Soviet republics that comprise it. In a general way, it aims to analyse the evolution of Central Asia from a peripheral region to an area that generates behaviours and receives the application of policies on the part ofinternational actors. In the first part of the study, it mentions a series of particularities of the republics that have determined the relationships in the region(the Central Asian order and those between the region and the outside world; it indicates geo-historical and economic-strategic aspects. In the second part, it examines the foreign policy of the republics in the post-Cold War era from the singularities of domestic policy. And, in the third part, it analyses, according to the aforementioned peculiarities, the policies that the area and each State has generated in international actors, both regional ones and global ones, and which have transformed the region from a peripheral one to a geopolitically emerging one.

  12. Formation of sulphation deposits in cables in the electricity generation plant of Los Humeros geothermal field, Mexico; Sulfatacion de cables en la central geotermoelectrica Los Humeros, Puebla, Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Vergara Rangel, Agustin [Comision Federal de Electricidad, Perote, Veracruz (Mexico)

    2000-12-01

    In the construction of a central electrical generation plant using geothermal fluids, high quality standards are applied in all aspects of engineering. Los Humeros generation units were installed through trenches, ducts and trays according to norms for cables of control, force and power, specifically in point to point cables and connections. Performance of the power plant has been affected by electric momentary and sequence flaws due to problems of cable sulfating, which were solved by tinning the conductors. [Spanish] En la construccion de centrales generadoras de electricidad con fluidos geotermicos se aplican criterios de calidad de diseno en todos los aspectos de la ingenieria. En Los Humeros Puebla, se realizo la instalacion conforme a normas de cables de control, fuerza y potencia a traves de trincheras, ductos y charolas y especificamente en el cableado asi como en las conexiones de punta a punta. Todos estos aspectos son referidos a planos de los componentes y equipos electricos existentes en una central. Al paso del tiempo existieron fallas electricas momentaneas y secuenciales por el problema de sulfatacion en cables, los cuales fueron resueltos con el estanado de conductores.

  13. Are Dietary Patterns of Mothers during Pregnancy Related to Childrens Weight Status? Evidence from the Lifeways Cross-Generational Cohort Study

    Directory of Open Access Journals (Sweden)

    Celine M Murrin

    2015-07-01

    Full Text Available Children's diet patterns are likely to be influenced by their mothers' diet pattern. The primary objective of this study was to examine whether children's adiposity could be influenced by diet patterns of mothers during pregnancy. A secondary objective was to study the relative influence of fathers' and children's dietary patterns on childhood adiposity. The design was a prospective cross-generational cohort study initiated with 1,124 mothers recruited during pregnancy. Self-reported questionnaires included a food frequency instrument (FFQ to assess parental intakes during the perinatal period. Child body mass index (BMI was measured at 5 years and an age-appropriate FFQ was administered. Dietary patterns for each group were identified by principal components analysis. Pearson's correlation and logistic regression were used to test for associations. Dietary patterns were described for n = 1,042 mothers during pregnancy and n = 331 fathers during the perinatal period. Dietary patterns and BMI data were available for n = 443 children at age 5 years. The diet patterns identified for mothers correlated with the corresponding diet patterns for fathers. The children's “pasta & vegetable” pattern was positively correlated with “healthy patterns” in mothers (r = 0.195, p < 0.01 and fathers (r = 0.250, p < 0.01. The children's “junk” food pattern was correlated with the “processed” pattern in mothers (r = 0.245, p < 0.01 and fathers (r = 0.257, p < 0.01. In multivariate logistic regression analysis the upper tertiles of children's “cereal and juice” [Tertile 2 (T2: OR 0.44, 95% CI (0.22-0.90; T3: 0.41, (0.19-0.85] and the middle tertile of the “pasta and veg” patterns [T3: 0.37, (0.18-0.75] were negatively associated with overweight and obesity. The mothers' processed pattern during pregnancy was positively associated with offspring overweight and obesity [T2: 2.64, (1.28-5.45; T3: 2.03, (0.87-4.73]. No significant associations

  14. A Comparison of Optimal Operation of a Residential Fuel Cell Co-Generation System Using Clustered Demand Patterns Based on Kullback-Leibler Divergence

    Directory of Open Access Journals (Sweden)

    Takumi Hasizume

    2013-01-01

    Full Text Available When evaluating residential energy systems like co-generation systems, hot water and electricity demand profiles are critical. In this paper, the authors aim to extract basic time-series demand patterns from two kinds of measured demand (electricity and domestic hot water, and also aim to reveal effective demand patterns for primary energy saving. Time-series demand data are categorized with a hierarchical clustering method using a statistical pseudo-distance, which is represented by the generalized Kullback-Leibler divergence of two Gaussian mixture distributions. The classified demand patterns are built using hierarchical clustering and then a comparison is made between the optimal operation of a polymer electrolyte membrane fuel cell co-generation system and the operation of a reference system (a conventional combination of a condensing gas boiler and electricity purchased from the grid using the appropriately built demand profiles. Our results show that basic demand patterns are extracted by the proposed method, and the heat-to-power ratio of demand, the amount of daily demand, and demand patterns affect the primary energy saving of the co-generation system.

  15. Heparan sulphation patterns generated by specific heparan sulfotransferase enzymes direct distinct aspects of retinal axon guidance at the optic chiasm.

    Science.gov (United States)

    Pratt, Thomas; Conway, Christopher D; Tian, Natasha M M-L; Price, David J; Mason, John O

    2006-06-28

    Retinal ganglion cell (RGC) axons from each eye execute a series of maneuvers as they converge on the ventral surface of the brain at the optic chiasm for sorting into the optic tracts. Heparan sulfate proteoglycans (HSPGs) are extracellular glycoproteins involved in cell-surface interactions. HSPGs exhibit massive structural diversity, conferred partly by extensive post-translational modification including differential sulfation. Here we examine the roles of HSPG sulfation in RGC axon guidance at the chiasm. We identified different axon navigation phenotypes in two heparan sulfate sulfotransferase (Hst) mutant embryos, Hs2st-/- and Hs6st1-/-, each lacking an enzyme that catalyzes a particular HSPG modification. Hs2st-/- embryos display axon disorganization at the chiasm. Hs6st1-/- embryos exhibit prolific inter-retinal innervation. We show that RGCs express Hs2st and Hs6st1 and that navigation errors made by their axons coincide with regions of high Hs2st and/or Hs6st1 expression at the chiasm. Slit proteins are expressed at particular locations in the retina and around the chiasm and are normally deployed to prevent axons entering inappropriate territories. We show that Hs2st and/or Hs6st1 expression coincides with Slit expression domains at locations where RGC axons make navigation errors in Hs2st-/- and Hs6st1-/- mutants and that Hs6st1-/- RGC axons are less sensitive to Slit2 repulsion than their wild-type counterparts in vitro. We suggest that (1) Hs2st and Hs6st1 are each deployed to generate distinct patterns of heparan sulfation on RGCs and at the optic chiasm and (2) this differential sulfation directs retinal axons through the chiasm, at least in part by modulating the response of the navigating growth cone to Slit proteins. PMID:16807321

  16. Modelling forest lines and forest distribution patterns with remote sensing data in a mountainous region of semi-arid Central Asia

    Directory of Open Access Journals (Sweden)

    M. Klinge

    2014-10-01

    Full Text Available Satellite images and digital elevation models provide an excellent database to analyse forest distribution patterns and forest limits in the mountain regions of semi-arid Central Asia at the regional scale. For the investigation area in the northern Tien Shan a strong relation between forest distribution and climate conditions could be found. Additionally areas of potential human impact on forested areas are identified at lower elevations near the mountain border based on an analysis of the differences of climatic preconditions and present occurrence of forest stands. The distribution of spruce (Picea schrenkiana forests is hydrologically limited by a minimum annual precipitation of 250 mm and thermally by a minimum monthly mean temperature of 5 °C during the growing season. While the actual lower forest limit increases from 1600 m a.s.l. in the northwest to 2600 m a.s.l. in the southeast, the upper forest limit takes the same course from 1800 to 2900 m a.s.l. In accordance with the main wind directions, the steepest gradient of both forest lines and the greatest local vertical extent of the forest belt of 500 to 600 m and maximum 900 m occur at the northern and western mountain fronts. The forests in the investigation area are strongly restricted to north facing-slopes, which is a common feature in semi-arid Central Asia. Based on the presumption that variations in local climate conditions are a function of topography, the potential forest extent was analysed with regard to the parameters slope, aspect, solar radiation input and elevation. All four parameters showed a strong relationship to forest distribution, yielding a total potential forest area that is 3.5 times larger than the present forest remains of 502 km2.

  17. Modelling forest lines and forest distribution patterns with remote sensing data in a mountainous region of semi-arid Central Asia

    Science.gov (United States)

    Klinge, M.; Böhner, J.; Erasmi, S.

    2014-10-01

    Satellite images and digital elevation models provide an excellent database to analyse forest distribution patterns and forest limits in the mountain regions of semi-arid Central Asia at the regional scale. For the investigation area in the northern Tien Shan a strong relation between forest distribution and climate conditions could be found. Additionally areas of potential human impact on forested areas are identified at lower elevations near the mountain border based on an analysis of the differences of climatic preconditions and present occurrence of forest stands. The distribution of spruce (Picea schrenkiana) forests is hydrologically limited by a minimum annual precipitation of 250 mm and thermally by a minimum monthly mean temperature of 5 °C during the growing season. While the actual lower forest limit increases from 1600 m a.s.l. in the northwest to 2600 m a.s.l. in the southeast, the upper forest limit takes the same course from 1800 to 2900 m a.s.l. In accordance with the main wind directions, the steepest gradient of both forest lines and the greatest local vertical extent of the forest belt of 500 to 600 m and maximum 900 m occur at the northern and western mountain fronts. The forests in the investigation area are strongly restricted to north facing-slopes, which is a common feature in semi-arid Central Asia. Based on the presumption that variations in local climate conditions are a function of topography, the potential forest extent was analysed with regard to the parameters slope, aspect, solar radiation input and elevation. All four parameters showed a strong relationship to forest distribution, yielding a total potential forest area that is 3.5 times larger than the present forest remains of 502 km2.

  18. Soil cover patterns influence on the land environmental functions, agroecological quality, land-use and monitoring efficiency in the Central Russia

    Science.gov (United States)

    Vasenev, Ivan; Yashin, Ivan; Lukin, Sergey; Valentini, Riccardo

    2015-04-01

    First decades of XXI century actualized for soil researches the principal methodical problem of most modern geosciences: what spatial and temporal scale would be optimal for land quality evaluation and land-use practice optimizing? It is becoming obvious that this question cannot have one solution and have to be solved with especial attention on the features of concrete region and landscape, land-use history and practical issues, land current state and environmental functions, soil cover patterns and variability, governmental requirements and local society needs, best available technologies and their potential profitability. Central Russia is one of the most dynamical economic regions with naturally high and man-made complicated landscape and soil cover variability, long-term land-use history and self-contradictory issues, high potential of profitable farming and increased risks of land degradation. Global climate and technological changes essentially complicate the originally high and sharply increased in XX century farming land heterogeneity in the Central Russia that actualizes system analysis of its zonal, intra-zonal and azonal soil cover patterns according to their influence on land environmental functions, agroecological quality, and land-use and monitoring efficiency variability. Developed by the Laboratory of agroecological monitoring, ecosystem modeling & prediction (LAMP / RTSAU with support of RF Governmental projects #11.G34.31.0079 and #14.120.14.4266) regional systems of greenhouse gases environmental monitoring RusFluxNet (6 fixed & 1 mobile eddy covariance stations with zonal functional sets of key plots with chamber investigations in 5 Russian regions) and of agroecological monitoring (in representative key plots with different farming practice in 9 RF regions) allow to do this analysis in frame of enough representative regional multi-factorial matrix of soil cover patterns, bioclimatic conditions, landscape features, and land-use history and

  19. Next generation of non-mammalian blood-brain barrier models to study parasitic infections of the central nervous system

    Science.gov (United States)

    Siddiqui, Ruqaiyyah; Edwards-Smallbone, James; Flynn, Robin; Khan, Naveed Ahmed

    2012-01-01

    Transmigration of neuropathogens across the blood-brain barrier is a key step in the development of central nervous system infections, making it a prime target for drug development. The ability of neuropathogens to traverse the blood-brain barrier continues to inspire researchers to understand the specific strategies and molecular mechanisms that allow them to enter the brain. The availability of models of the blood-brain barrier that closely mimic the situation in vivo offers unprecedented opportunities for the development of novel therapeutics. PMID:21921682

  20. Characterization of alternative electric generation technologies for the SPS comparative assessment: volume 2, central-station technologies

    International Nuclear Information System (INIS)

    The SPS Concept Development and Evaluation Program includes a comparative assessment. An early first step in the assessment process is the selection and characterization of alternative technologies. This document describes the cost and performance (i.e., technical and environmental) characteristics of six central station energy alternatives: (1) conventional coal-fired powerplant; (2) conventional light water reactor (LWR); (3) combined cycle powerplant with low-Btu gasifiers; (4) liquid metal fast breeder reactor (LMFBR); (5) photovoltaic system without storage; and (6) fusion reactor

  1. A double burden of overall or central adiposity and anemia or iron deficiency is prevalent but with little socioeconomic patterning among Moroccan and Tunisian urban women.

    Science.gov (United States)

    Gartner, Agnès; El Ati, Jalila; Traissac, Pierre; Bour, Abdellatif; Berger, Jacques; Landais, Edwige; El Hsaïni, Houda; Ben Rayana, Chiheb; Delpeuch, Francis

    2014-01-01

    In North Africa, overnutrition has dramatically increased with the nutrition transition while micronutrient deficiencies persist, resulting in clustering of opposite types of malnutrition that can present a unique difficulty for public health interventions. We assessed the magnitude of the double burden of malnutrition among urban Moroccan and Tunisian women, as defined by the coexistence of overall or central adiposity and anemia or iron deficiency (ID), and explored the sociodemographic patterning of individual double burden. In cross-sectional surveys representative of the region around the capital city, we randomly selected 811 and 1689 nonpregnant women aged 20-49 y in Morocco and Tunisia, respectively. Four double burdens were analyzed: overweight (body mass index ≥25 kg/m(2)) or increased risk abdominal obesity (waist circumference ≥80 cm) and anemia (blood hemoglobin education groups. Generally, the rare, associated sociodemographic factors varied across the 4 subject-level double burdens and the 2 countries and differed from those usually associated with adiposity, anemia, or ID. Any double burden combining adiposity and anemia or ID should therefore be taken into consideration in all women. This trial was registered at clinicaltrials.gov as NCT01844349. PMID:24198310

  2. Three-dimensional cooling pattern of a granitic pluton 2. The study of deuteric sub-solidus reactions in the Toki granite, Central Japan

    International Nuclear Information System (INIS)

    Petrographical studies examining the development and variations of sub-solidus reactions recorded in the Toki granite represent the three-dimensional cooling pattern of this zoned pluton in Central Japan. Samples collected from 19 boreholes in the Toki granite show characteristics indicative of spatial variations in the extent of the sub-solidus reactions. Exsolution coarsening has produced microperthite, including albite-rich lamellae, in this pluton, while deuteric coarsening has resulted in the formation of patchperthite, myrmekite, and the reaction rim. The extent of the deuteric coarsening reactions can be evaluated from the width and spacing of the albite-rich patch in patchperthite and from the thickness of myrmekite and the reaction rim. The width, spacing, and thickness of these textural features increase systematically with elevation; they also increase gradually in the horizontal inward direction in the western part of the pluton but not in the eastern part of the pluton. The systematic variations in textural development indicate that the Toki granite cooled effectively from the roof and from the western margin during the deuteric coarsening stage. The deuteric coarsening may have occurred at temperatures below 500°C, as indicated by ternary feldspar thermometry. (author)

  3. Generational changes in materialism and work centrality, 1976-2007: associations with temporal changes in societal insecurity and materialistic role modeling.

    Science.gov (United States)

    Twenge, Jean M; Kasser, Tim

    2013-07-01

    We examined whether culture-level indices of threat, instability, and materialistic modeling were linked to the materialistic values of American 12th graders between 1976 and 2007 (N = 355,296). Youth materialism (such as the importance of money and of owning expensive material items) increased over the generations, peaking in the late 1980s to early 1990s with Generation X and then staying at historically high levels for Millennials (GenMe). Societal instability and disconnection (e.g., unemployment, divorce) and social modeling (e.g., advertising spending) had both contemporaneous and lagged associations with higher levels of materialism, with advertising most influential during adolescence and instability during childhood. Societal-level living standards during childhood predicted materialism 10 years later. When materialistic values increased, work centrality steadily declined, suggesting a growing discrepancy between the desire for material rewards and the willingness to do the work usually required to earn them. PMID:23637277

  4. A Priori and a Posteriori Dietary Patterns during Pregnancy and Gestational Weight Gain: The Generation R Study

    Directory of Open Access Journals (Sweden)

    Myrte J. Tielemans

    2015-11-01

    Full Text Available Abnormal gestational weight gain (GWG is associated with adverse pregnancy outcomes. We examined whether dietary patterns are associated with GWG. Participants included 3374 pregnant women from a population-based cohort in the Netherlands. Dietary intake during pregnancy was assessed with food-frequency questionnaires. Three a posteriori-derived dietary patterns were identified using principal component analysis: a “Vegetable, oil and fish”, a “Nuts, high-fiber cereals and soy”, and a “Margarine, sugar and snacks” pattern. The a priori-defined dietary pattern was based on national dietary recommendations. Weight was repeatedly measured around 13, 20 and 30 weeks of pregnancy; pre-pregnancy and maximum weight were self-reported. Normal weight women with high adherence to the “Vegetable, oil and fish” pattern had higher early-pregnancy GWG than those with low adherence (43 g/week (95% CI 16; 69 for highest vs. lowest quartile (Q. Adherence to the “Margarine, sugar and snacks” pattern was associated with a higher prevalence of excessive GWG (OR 1.45 (95% CI 1.06; 1.99 Q4 vs. Q1. Normal weight women with higher scores on the “Nuts, high-fiber cereals and soy” pattern had more moderate GWG than women with lower scores (−0.01 (95% CI −0.02; −0.00 per SD. The a priori-defined pattern was not associated with GWG. To conclude, specific dietary patterns may play a role in early pregnancy but are not consistently associated with GWG.

  5. Alternative mRNA Splicing from the Glial Fibrillary Acidic Protein (GFAP) Gene Generates Isoforms with Distinct Subcellular mRNA Localization Patterns in Astrocytes

    DEFF Research Database (Denmark)

    Thomsen, Rune; Daugaard, Tina Fuglsang; Holm, Ida E;

    2013-01-01

    The intermediate filament network of astrocytes includes Glial fibrillary acidic protein (Gfap) as a major component. Gfap mRNA is alternatively spliced resulting in generation of different protein isoforms where Gfapa is the most predominant isoform. The Gfapd isoform is expressed in proliferating...... mRNA localization patterns were dependent on the different 39-exon sequences included in Gfapd and Gfapa mRNA. The presented results show that alternative Gfap mRNA splicing results in isoform-specific mRNA localization patterns with resulting different local mRNA concentration ratios which have...

  6. Evidence of binary division in mature central capsules of a collosphaerid colonial radiolarian: Implications for shell ontogenetic patterns in modern and fossil species

    Digital Repository Service at National Institute of Oceanography (India)

    Anderson, O.R.; Gupta, S.M.

    collosphaerid radiolaria, at least, proliferation of central capsules can occur after maturation and may account for rapid increase in biomass and population size in response to favourable environments. This augments prior evidence that central capsules of non...

  7. Focusing by blocking: Repeatedly generating central density peaks in self-propelled particle systems by exploiting diffusive processes

    Science.gov (United States)

    Menzel, Andreas M.

    2015-05-01

    Over the past few years the displacement statistics of self-propelled particles has been intensely studied, revealing their long-time diffusive behavior. Here, we demonstrate that a concerted combination of boundary conditions and switching on and off the self-propelling drive can generate and afterwards arbitrarily often restore a non-stationary centered peak in their spatial distribution. This corresponds to a partial reversibility of their statistical behavior, in opposition to the above-mentioned long-time diffusive nature. Interestingly, it is a diffusive process that mediates and makes possible this procedure. It should be straightforward to verify our predictions in a real experimental system.

  8. Patterns of landscape form in the upper Rhône basin, Central Swiss Alps, predominantly show lithologic controls despite multiple glaciations and variations in rock uplift rates

    Science.gov (United States)

    Stutenbecker, L. A.; Costa, A.; Schlunegger, F.

    2015-10-01

    The development of topography is mainly dependent on the interplay of uplift and erosion, which are in term controlled by various factors including climate, glaciers, lithology, seismic activity and short-term variables such as anthropogenic impact. While most studies have focused on the role of tectonics and climate on the landscape form and underlying processes, less attention has been paid on exploring the controls of lithology on erosion. The Central European Alps are characterized by a large spatial variability in exposed lithologies and as such offer an ideal laboratory to investigate the lithological controls on erosion and landscape form. Here, we focus on the ca. 5400 km2-large upper Rhône basin situated in the Central Swiss Alps to explore how the lithological architecture of the bedrock conditions the Alpine landscape. To this extent, we extract geomorphological parameters along the channels of ca. 50 tributary basins, whose catchments are located in either granitic basement rocks (External massifs), oceanic meta-sedimentary and ophiolitic rocks (Penninic nappes) or fine-grained continental-margin sediments (Helvetic nappes). The analysis of longitudinal river profiles show that all tributary rivers within the Rhône basin are in topographic transient state as testified by mainly convex or concave-convex longitudinal stream channel profiles with several knickpoints of either tectonic or glacial origin. In addition, although the entire Rhône basin shows a strong glacial inheritance (and is still partly glaciated) and some of the highest uplift rates recently measured in the Alps, the river network has responded differently to those perturbations as revealed by the morphometric data. In particular, tributary basins in the Helvetic nappes are the most equilibrated (concave river profiles, overall lower elevations, less steep slope gradients and lowest hypsometric integrals), while the tributaries located in the External massifs are least equilibrated

  9. Conditions for Multi-functionality in a Rhythm Generating Network Inspired by Turtle Scratching

    OpenAIRE

    Snyder, Abigail C.; Rubin, Jonathan E

    2015-01-01

    Rhythmic behaviors such as breathing, walking, and scratching are vital to many species. Such behaviors can emerge from groups of neurons, called central pattern generators, in the absence of rhythmic inputs. In vertebrates, the identification of the cells that constitute the central pattern generator for particular rhythmic behaviors is difficult, and often, its existence has only been inferred. For example, under experimental conditions, intact turtles generate several rhythmic scratch moto...

  10. Walk-off-induced modulation instability, temporal pattern formation, and frequency comb generation in cavity-enhanced second-harmonic generation

    CERN Document Server

    Leo, F; Ricciardi, I; De Rosa, M; Coen, S; Wabnitz, S; Erkintalo, M

    2016-01-01

    We derive a time-domain mean-field equation to model the full temporal and spectral dynamics of light in singly resonant cavity-enhanced second-harmonic generation systems. We show that the temporal walk-off between the fundamental and the second-harmonic fields plays a decisive role under realistic conditions, giving rise to rich, previously unidentified nonlinear behaviour. Through linear stability analysis and numerical simulations, we discover a new kind of quadratic modulation instability which leads to the formation of optical frequency combs and associated time-domain dissipative structures. Our numerical simulations show excellent agreement with recent experimental observations of frequency combs in quadratic nonlinear media [Phys. Rev. A 91, 063839 (2015)]. Thus, in addition to unveiling a new, experimentally accessible regime of nonlinear dynamics, our work enables predictive modeling of frequency comb generation in cavity-enhanced second-harmonic generation systems.

  11. Traditional Homegardens and Domestic Biomass Fuel Consumption Pattern in the Developing World: The Case of a South-Central Rural Village of Bangladesh

    Energy Technology Data Exchange (ETDEWEB)

    Mukul, S.A. (Dept. of Forestry and Environmental Science, School of Agriculture and Mineral sciences, Shahjalal Univ. of Science and Technology, Sylhet 3114 (Bangladesh)). E-mail: sharif_a_mukul@yahoo.com

    2008-10-15

    Peoples living in most developing countries meet majority of their biomass fuel requirements from the forest. However, this usual practice becomes difficult to maintain as the forest of this region decreases in an alarming rate. In such context, homegardens will have to play the key role in near future where in many forest poor regions it's already playing the vital role. An exploratory study was conducted in a south-central rural village of Bangladesh to realize this potential contribution of homegardens to households domestic biomass fuel supplies, which is as well a virtually forest poor region of the country. Households were grouped into three different land holding categories and a total of thirty respondents, 10 from each category were selected randomly to understand their domestic biomass fuel consumption pattern as well as the role of homegardens to meet this fuel supply. Study suggested that, majority (87%) of the households of the area rely extensively on their homegardens to meet their domestic cooking energy requirements. During the study 47 homestead species were identified having fuel value of which 12 were identified as the most preferred species in the area. The contribution of wood fuel in households domestic energy sharing was reported as 56% followed by dried leaves (21%), dung cake/sticks (14%), crop residues (6%) and others (3%). Study finally concluded for a rich homegarden system in forest near regions to conserve country's remaining forest by providing an alternative source of biomass fuel. A participatory management of governments' fallow and khas lands, public places including road, railway and canal banks for tree farming to benefit rural land-less and marginal people were also recommended

  12. Reducing False Alarms of Annual Forecast in the Central China North-South Seismic Belt by Reverse Tracing of Precursors (RTP) Using the Pattern Informatics (PI) `Hotspots'

    Science.gov (United States)

    Zhang, Shengfeng; Wu, Zhongliang; Jiang, Changsheng

    2016-05-01

    The annual consultation on the likelihood of earthquakes in the next year, the `Annual Consultation Meeting', has been one of the most important forward forecast experiments organized by the China Earthquake Administration (CEA) since the 1970s, in which annual alarm regions are identified by an expert panel considering multi-disciplinary `anomalies'. In such annual forecasts, one of the problems in need of further technical solution is its false alarms. To tackle this problem, the concept of `reverse tracing of precursors (RTP)' is used to the annual consultation, as a temporal continuation and spatial extension of the work of Zuc(hao) et al. (Pure Appl Geophys 167:783-800, 2010). The central China north-south seismic belt (in connection to the CSEP testing region) is selected as the testing region of such an approach. Applying the concept of RTP, for an annual alarm region delineated by the Annual Consultation Meeting, the distribution of `hotspots' of the pattern informatics (PI), which targets the 5-year-scale seismic hazard, is considered. The `hit', or successful forecast, of the annual seismic hazard is shown to be related to the sufficient coverage of the `hotspots' within the annual alarm region. The ratio of the areas of the `hotspots' over the whole area of the annual alarm region is thus used to identify the false alarms which have few `hotspots'. The results of the years 2004-2012 show that using a threshold of 17 % can reduce 34 % (13 among 38) of the false alarms without losing the successful hit (being 6 in that period).

  13. A prospective study of magnetic resonance imaging patterns of central nervous system infections in pediatric age group and young adults and their clinico-biochemical correlation

    Directory of Open Access Journals (Sweden)

    Kamini Gupta

    2016-01-01

    Full Text Available Background: Infections of the central nervous system (CNS are common and routinely encountered. Our aim was to evaluate the neuroimaging features of the various infections of the CNS so as to differentiate them from tumoral, vascular, and other entities that warrant a different line of therapy. Aims: Our aim was to analyze the biochemical and magnetic resonance imaging (MRI features in CNS infections. Settings and Design: This was a longitudinal, prospective study over a period of 1½ years. Subjects and Methods: We studied cerebrospinal fluid (CSF findings and MRI patterns in 27 patients of 0–20 years age group with clinical features of CNS infections. MRI was performed on MAGNETOM Avanto 18 Channel 1.5 Tesla MR machine by Siemens India Ltd. The MRI protocol consisted of diffusion-weighted and apparent diffusion coefficient imaging, turbo spin echo T2-weighted, spin echo T1-weighted, fluid-attenuated inversion recovery (FLAIR, and gradient-echo in axial, FLAIR in coronal, and T2-weighted in sagittal plane. Contrast-enhanced T1-weighted sequence and MR spectroscopy were done whenever indicated. Results and Conclusions: We found that most of the children belong to 1–10 years age group. Fungal infections were uncommon, mean CSF adenosine deaminase values specific for tuberculosis and mean CSF glucose-lowered in pyogenic. Hemorrhagic involvement of thalamus with/without basal ganglia and brainstem involvement may indicate Japanese encephalitis or dengue encephalitis. Diffusion restriction or hemorrhage in not expected in the brainstem afflicted lesions of rabies. Congenital cytomegalovirus can cause cortical malformations. T1 hyperintensities with diffusion restriction may represent viral encephalitis. Lesions of acute disseminated encephalomyelitis (ADEM may mimic viral encephalitis. Leptomeningeal enhancement is predominant in pyogenic meningitis. Basilar meningitis in the presence of tuberculomas is highly sensitive and specific for

  14. Soil cover patterns influence on the land environmental functions, agroecological quality, land-use and monitoring efficiency in the Central Russia

    Science.gov (United States)

    Vasenev, Ivan; Yashin, Ivan; Lukin, Sergey; Valentini, Riccardo

    2015-04-01

    First decades of XXI century actualized for soil researches the principal methodical problem of most modern geosciences: what spatial and temporal scale would be optimal for land quality evaluation and land-use practice optimizing? It is becoming obvious that this question cannot have one solution and have to be solved with especial attention on the features of concrete region and landscape, land-use history and practical issues, land current state and environmental functions, soil cover patterns and variability, governmental requirements and local society needs, best available technologies and their potential profitability. Central Russia is one of the most dynamical economic regions with naturally high and man-made complicated landscape and soil cover variability, long-term land-use history and self-contradictory issues, high potential of profitable farming and increased risks of land degradation. Global climate and technological changes essentially complicate the originally high and sharply increased in XX century farming land heterogeneity in the Central Russia that actualizes system analysis of its zonal, intra-zonal and azonal soil cover patterns according to their influence on land environmental functions, agroecological quality, and land-use and monitoring efficiency variability. Developed by the Laboratory of agroecological monitoring, ecosystem modeling & prediction (LAMP / RTSAU with support of RF Governmental projects #11.G34.31.0079 and #14.120.14.4266) regional systems of greenhouse gases environmental monitoring RusFluxNet (6 fixed & 1 mobile eddy covariance stations with zonal functional sets of key plots with chamber investigations in 5 Russian regions) and of agroecological monitoring (in representative key plots with different farming practice in 9 RF regions) allow to do this analysis in frame of enough representative regional multi-factorial matrix of soil cover patterns, bioclimatic conditions, landscape features, and land-use history and

  15. Inertial-confinement fusion central-station electric-power-generating plant. Final report, March 1, 1979-September 30, 1980

    International Nuclear Information System (INIS)

    This report contains a complete description of the subsystems of the power plant including driver, driver power supply, pellet fabrication, pellet injection and aiming, data handling and control, evacuation, tritium and radwaste handling, first wall protection, first wall and structure, heat removal, tritium breeding and neutron shielding, maintenance and repair and balance of plant. In addition, it contains analytic support for the conceptual designs developed for each subsystem. The emphasis of the effort was on designing a viable reactor cavity and on solving the problems of interfacing the driver systems with the reactor cavity. The reactors generate 3500 MWt by irradiating a pellet whose gain is 175 from two opposite sides with a total of 2 MJ driver energy at a 10 Hz repetition rate. Because the nominal laser driver efficiency is 10% and that for the heavy ion driver is 30%, the net electric power outputs are 1207 MWe and 1346 MWe; the net plant conversion efficiencies are 28.1% and 31.3%; and the recirculating fractions are 22.9% and 14.0% respectively. The increased power output is, however, only one of the factors considered by utilities in performing a cost minimization analysis of competing power sources for system expansion. These other factors include: capital costs, cost of construction time, operating costs, environmental and licensing costs and reliability cost

  16. Inertial-confinement fusion central-station electric-power-generating plant. Final report, March 1, 1979-September 30, 1980

    International Nuclear Information System (INIS)

    This report contains a complete description of the subsystems of the power plant including driver, driver power supply, pellet fabrication, pellet injection and aiming, data handling and control, evacuation, tritium and radwaste handling, first wall protection, first wall and structure, heat removal, tritium breeding and neutron shielding, maintenance and repair and balance of plant. In addition, it contains analytic support for the conceptual designs developed for each subsystem. The emphasis of the effort was on designing a viable reactor cavity and on solving the problems of interfacing the driver systems with the reactor cavity. The reactors generate 3500 NWt by irradiating a pellet whose gain is 175 from two opposite sides with a total of 2 MJ driver energy at a 10 Hz repetition rate. Because the nominal laser driver efficiency is 10% and that for the heavy ion driver is 30%, the net electric power outputs are 1207 MWe and 1346 MWe; the net plant conversion efficiencies are 28.1% and 31.3%; and the recirculating fractions are 22.9% and 14.0% respectively. The increased power output is, however, only one of the factors considered by utilities in performing a cost minimization analysis of competing power sources for system expansion. These other factors include: capital costs, cost of construction time, operating costs, environmental and licensing costs and reliability cost

  17. Walk-Off-Induced Modulation Instability, Temporal Pattern Formation, and Frequency Comb Generation in Cavity-Enhanced Second-Harmonic Generation

    Science.gov (United States)

    Leo, F.; Hansson, T.; Ricciardi, I.; De Rosa, M.; Coen, S.; Wabnitz, S.; Erkintalo, M.

    2016-01-01

    We derive a time-domain mean-field equation to model the full temporal and spectral dynamics of light in singly resonant cavity-enhanced second-harmonic generation systems. We show that the temporal walk-off between the fundamental and the second-harmonic fields plays a decisive role under realistic conditions, giving rise to rich, previously unidentified nonlinear behavior. Through linear stability analysis and numerical simulations, we discover a new kind of quadratic modulation instability which leads to the formation of optical frequency combs and associated time-domain dissipative structures. Our numerical simulations show excellent agreement with recent experimental observations of frequency combs in quadratic nonlinear media [Phys. Rev. A 91, 063839 (2015)]. Thus, in addition to unveiling a new, experimentally accessible regime of nonlinear dynamics, our work enables predictive modeling of frequency comb generation in cavity-enhanced second-harmonic generation systems. We expect our findings to have wide impact on the study of temporal and spectral dynamics in a diverse range of dispersive, quadratically nonlinear resonators.

  18. Changes in the pattern of distribution of von Willebrand factor in rat aortic endothelial cells following thrombin generation in vivo.

    Science.gov (United States)

    Senis, Y A; Richardson, M; Tinlin, S; Maurice, D H; Giles, A R

    1996-04-01

    The pattern of distribution of von Willebrand factor (VWF) in relatively large sheets of rat aortic endothelial cells (EC) obtained by the Häutchen technique were analysed by immunocytochemistry and light microscopy. EC were examined pre and post administration of a procoagulant mixture of factor Xa (F.Xa) and phosphotidylcholine/phosphotidylserine (PCPS) vesicles which was demonstrated to result in the selective loss of high molecular weight multimers (HMWM) of plasma VWF in the rat. In placebo animals the pattern was heterogenous both in overall distribution and in individual cells which showed both a diffuse and granular pattern. Groups of intensely stained EC were oriented parallel to the longitudinal axis of the aorta and staining was particularly prominent around the orifices of the intercostal arteries, implicating shear-stress as a possible factor in VWF expression by EC. Changes in the pattern of distribution of staining were observed at various time points post-infusion of F.Xa/PCPS, suggesting the immediate release of VWF from EC stores followed by the recruitment of EC to synthesize and store VWF. These changes are consistent with the decrease in EC Weibel-Palade Body (WPB) content observed by EM in previously reported studies using this model. PMID:8611460

  19. Role of dietary patterns, sedentary behaviour and overweight of the longditudinal development of childhood constipation: The generation R Study

    NARCIS (Netherlands)

    Kiefte-de Jong, J.C.; Vries, de J.H.M.; Escher, J.; Jaddoe, V.W.; Hofman, M.K.; Raat, H.; Moll, H.

    2013-01-01

    The influence of childhood nutrition on the development of constipation beyond the period of weaning and breastfeeding is relatively understudied. In addition, eating patterns in childhood can be highly correlated with overweight and sedentary behaviour, which may also have an influence on constipat

  20. Resolution 147/012. It authorize the Central Libertador / SA aeolian generation company to generate an aeolian electricity source by an electric power generating plant located in Maldonado town 4 AA Catastral section, and the Sistema inerconectado Nacional connection

    International Nuclear Information System (INIS)

    This decree authorizes the generation of electricity using aeolian energy as the primary electricity source. This project was presented by the 'Libertador / S.A' aeolian generation company with the proposal to install an electrical plant in Maldonado town. This authorization is according to the Electric Wholesale Market regulation

  1. Satellite-measured interannual variability of turbid river plumes off central-southern Chile: Spatial patterns and the influence of climate variability

    Science.gov (United States)

    Saldías, Gonzalo S.; Largier, John L.; Mendes, Renato; Pérez-Santos, Iván; Vargas, Cristian A.; Sobarzo, Marcus

    2016-08-01

    Ocean color imagery from MODIS (Moderate Resolution Imaging Spectroradiometer) onboard the Aqua platform is used to characterize the interannual variability of turbid river plumes off central-southern Chile. Emphasis is placed on the influence of climate fluctuations, namely El Niño Southern Oscillation (ENSO), the Pacific Decadal Oscillation (PDO), and the Antarctic Oscillation (AAO). Additional satellite data on wind, boat-based hydrographic profiles, and regional climate indices are used to identify the influence of climate variability on the generation of anomalous turbid river plumes. The evolution of salinity at a coastal station on the 90 m isobath between the Itata and Biobío Rivers shows a freshwater surface layer with salinity < 32.5 and 5-10 m thick during major plume events in 2002, 2005 and 2006. Surface salinity minima are correlated with peaks in turbidy from the normalized water leaving radiance at 555 nm (nLw(555)), both representing turbid river plumes. EOF analysis reveals that major turbid plume events occurred primarily during warm phases of the ENSO and PDO, and negative phases of the AAO, when storm tracks are further north. Anomalously large turbid plumes extend long distances offshore (∼ 70-80 km), and individual plumes coalesce into a continuous plume along the coast that covers the entire continental shelf. Season-specific correlation analyses reveal an increased influence of the AAO on river plumes south of Punta Lavapié in spring-summer (negative correlation). North of this major cape, ENSO and PDO indices have a dominant influence on plumes with positive correlations with the nLw(555) signal in winter (and negative in summer). We discuss the biogeochemical implications of plume events and the importance of long-term and high-resolution ocean color observations for studying the temporal evolution of river plumes.

  2. Use of adaptive network burst detection methods for multielectrode array data and the generation of artificial spike patterns for method evaluation

    Science.gov (United States)

    Mendis, G. D. C.; Morrisroe, E.; Petrou, S.; Halgamuge, S. K.

    2016-04-01

    Objective. Multielectrode arrays are an informative extracellular recording technology that enables the analysis of cultured neuronal networks and network bursts (NBs) are a dominant feature observed in these recordings. This paper focuses on the validation of NB detection methods on different network activity patterns and developing a detection method that performs robustly across a wide variety of activity patterns. Approach. A firing rate based approach was used to generate artificial spike timestamps where NBs were introduced as episodes where the probability of spiking increases. Variations in firing and bursting characteristics were also included. In addition, an improved methodology of detecting NBs is proposed, based on time-binned average firing rates and time overlaps of single channel bursts. The robustness of the proposed method was compared against three existing algorithms using simulated, publicly available and newly acquired data. Main results. A range of activity patterns were generated by changing simulation variables that correspond to NB duration (40-2200 ms), intervals (0.3-16 s), firing rates (0.1-1 spikes s-1), local burst percentage (0%-90%), number of channels in local bursts (20-40) as well as the number of tonic and frequently-bursting channels. By extracting simulation parameters directly from real data, we generated synthetic data that closely resemble activity of mouse and rat cortical cultures at native and chemically perturbed states. In 50 simulated data sets with randomly selected parameter values, the improved NB detection method performed better (ascertained by the f-measure) than three existing methods (p neuronal activity patterns. Furthermore, it proposes an improved NB detection method that can be used robustly across a range of data types.

  3. Practice patterns for prostate cancer in nine central and northern Italy radiation oncology centers: a survey including 1759 patients treated during two decades (1980-1998)

    International Nuclear Information System (INIS)

    Purpose: Prostate cancer patients in Italy are offered the choice of the full spectrum of possible treatment options for their disease, but the diffusion of the more recent technological refinements among the Radiation Oncology centers is not homogeneous and there is a need to establish a reference 'historical' data source. This retrospective study describes the changing patterns in prostate cancer patient practice and the therapeutic results obtained in nine Radiation Oncology centers of Northern and Central Italy (five in Northern Italy and four in Central Italy). Methods and Materials: A total of 1759 prostate cancer patients, radically treated in the nine radiotherapy (RT) centers between 1980 and 1998, made up the study population. Data collected for each patient included clinical, pathologic, therapeutic features, and toxicity. The overall survival, disease-specific survival (DSS), and clinical relapse-free survival (RFS) were calculated for the whole series and for the subsets of patients defined by different clinical, pathologic, and therapeutic features, according to three accrual periods (A, 1980-1990; B, 1991-1994; and C, 1995-1998). Univariate and multivariate analyses were performed to identify prognostic factors related to survival and late adverse effects (cystitis and proctitis) probability. Results: Patient accrual increased markedly during the 2 decades considered, and the percentage of cases with Stage C or D disease dropped from 49% (period A) to 43% (period B) to 37% (period C) (p6 Gy in 44%, 84%, and 93% of the patients treated in period A, B, and C, respectively); a reduction in treated volumes, including pelvic lymphatic drainage (56-39% before 1995, 22% thereafter); and an increase in cases treated in association with hormonal therapy (50% before 1991, 80% thereafter). Lower energy (<10 MV) photon beams were progressively abandoned (12% before 1990 vs. 6-7% thereafter), along with an increase in the use of blocks (60% in the last 4 years of

  4. Effects of Temporal Wind Patterns on the Value of Wind-Generated Electricity in California and the Northwest

    Energy Technology Data Exchange (ETDEWEB)

    Wiser, Ryan H; Wiser, Ryan H; Fripp, Matthias

    2008-05-01

    Wind power production is variable, but also has diurnal and seasonal patterns. These patterns differ between sites, potentially making electric power from some wind sites more valuable for meeting customer loads or selling in wholesale power markets. This paper investigates whether the timing of wind significantly affects the value of electricity from sites in California and the Northwestern United States. We use both measured and modeled wind data and estimate the time-varying value of wind power with both financial and load-based metrics. We find that the potential difference in wholesale market value between better-correlated and poorly correlated wind sites is modest, on the order of 5-10 percent. A load-based metric, power production during the top 10 percent of peak load hours, varies more strongly between sites, suggesting that the capacity value of different wind projects could vary by as much as 50 percent based on the timing of wind alone.

  5. Sparse approaches for the exact distribution of patterns in long multi-states sequences generated by a Markov source

    CERN Document Server

    Nuel, Grégory

    2010-01-01

    We present two novel approaches for the computation of the exact distribution of a pattern in a long sequence. Both approaches take into account the sparse structure of the problem. The first approach relies on a partial recursion computing the largest eigenvalue of the the transition matrix of a Markov chain embedding. The second approach uses fast Taylor expansions of an exact bivariate rational reconstruction of the distribution. We illustrate the interest of both approaches on a simple toy-example and two biological applications: the transcription factors of the Human Chromosome 5 and the PROSITE signatures of functional motifs in proteins. On these examples our methods demonstrate their complementarity and their hability to extend the domain of feasibility for exact computations in pattern problems to a new level.

  6. Non-neutralized Electric Current Patterns in Solar Active Regions: Origin of the Shear-Generating Lorentz Force

    CERN Document Server

    Georgoulis, Manolis K; Mikic, Zoran

    2012-01-01

    Using solar vector magnetograms of the highest available spatial resolution and signal-to-noise ratio we perform a detailed study of electric current patterns in two solar active regions: a flaring/eruptive, and a flare-quiet one. We aim to determine whether active regions inject non-neutralized (net) electric currents in the solar atmosphere, responding to a debate initiated nearly two decades ago that remains inconclusive. We find that well-formed, intense magnetic polarity inversion lines (PILs) within active regions are the only photospheric magnetic structures that support significant net current. More intense PILs seem to imply stronger non-neutralized current patterns per polarity. This finding revises previous works that claim frequent injections of intense non-neutralized currents by most active regions appearing in the solar disk but also works that altogether rule out injection of non-neutralized currents. In agreement with previous studies, we also find that magnetically isolated active regions re...

  7. Aspects of seasonality and flood generating circulation patterns in a mountainous catchment in south-eastern Germany

    OpenAIRE

    Petrow, Th.; B. Merz; Lindenschmidt, K.-E.; Thieken, A. H.

    2007-01-01

    Analyses of discharge series, precipitation fields and flood producing atmospheric circulation patterns reveal that two governing flood regimes exist in the Mulde catchment in south-eastern Germany: frequent floods during the winter and less frequent but sometimes extreme floods during the summer. Differences in the statistical parameters of the discharge data can be found within the catchment from west to east. The discharges are compared to a number of landscape parameters that influence th...

  8. Movement pattern, power generation and well-being in children and young adults with spastic unilateral cerebral palsy

    OpenAIRE

    Riad, Jacques

    2011-01-01

    Patients with unilateral cerebral palsy (CP) all walk, most of them without great difficulty and without assistive devices. However, their walk tends to catch the eye because of abnormal, often asymmetrical movement in the upper and lower extremities. Although the impairment is limited and the involvement often is considered mild the deviation is apparent in both movement pattern and anatomy, with one leg being smaller and shorter. Some of the patients have a more severe CP diagnosis...

  9. Automatic Locomotion Generation for a UBot Modular Robot – Towards Both High-speed and Multiple Patterns

    Directory of Open Access Journals (Sweden)

    Jie Zhao

    2015-04-01

    Full Text Available Modular self-reconfigurable robots (SRRs have redundant degrees of freedom and various configurations. There are two hard problems imposed by SRR features: locomotion planning and the discovery of multiple locomotion patterns. Most of the current research focuses on solving the first problem, using evolutionary algorithms based on the philosophy of searching-for-the-best. The main problem is that the search can fall into a local optimum in the case of a complex non-linear problem. Another drawback is that the searched result lacks diversity in the behaviour space, which is inappropriate in addressing the problem of discovering multiple locomotion patterns. In this paper, we present a new strategy that evolves an SRR’s controller by searching for behavioural diversity. Instead of converging on a single optimal solution, this strategy discovers a vast variety of different ways to realize robot locomotion. Optimal motion is sparse in the behaviour space, and this method can find it as a by-product through a diversity-keeping mechanism. A revised particle swarm optimization (PSO algorithm, driven by behaviour sparseness, is implemented to evolve locomotion for a variety of configurations whose efficiency and flexibility is validated. The results show that this method can not only obtain an optimized robot controller, but also find various locomotion patterns.

  10. Sequencing of Local Therapy Affects the Pattern of Treatment Failure and Survival in Children With Atypical Teratoid Rhabdoid Tumors of the Central Nervous System

    International Nuclear Information System (INIS)

    Purpose: To assess the pattern of treatment failure associated with current therapeutic paradigms for childhood atypical teratoid rhabdoid tumors (AT/RT). Methods and Materials: Pediatric patients with AT/RT of the central nervous system treated at our institution between 1987 and 2007 were retrospectively evaluated. Overall survival (OS), progression-free survival, and cumulative incidence of local failure were correlated with age, sex, tumor location, extent of disease, and extent of surgical resection. Radiotherapy (RT) sequencing, chemotherapy, dose, timing, and volume administered after resection were also evaluated. Results: Thirty-one patients at a median age of 2.3 years at diagnosis (range, 0.45–16.87 years) were enrolled into protocols that included risk- and age-stratified RT. Craniospinal irradiation with focal tumor bed boost (median dose, 54 Gy) was administered to 18 patients. Gross total resection was achieved in 16. Ten patients presented with metastases at diagnosis. RT was delayed more than 3 months in 20 patients and between 1 and 3 months in 4; 7 patients received immediate postoperative irradiation preceding high-dose alkylator-based chemotherapy. At a median follow-up of 48 months, the cumulative incidence of local treatment failure was 37.5% ± 9%; progression-free survival was 33.2% ± 10%; and OS was 53.5% ± 10%. Children receiving delayed RT (≥1 month postoperatively) were more likely to experience local failure (hazard ratio [HR] 1.23, p = 0.007); the development of distant metastases before RT increased the risk of progression (HR 3.49, p = 0.006); and any evidence of disease progressionbefore RT decreased OS (HR 20.78, p = 0.004). Disease progression occurred in 52% (11/21) of children with initially localized tumors who underwent gross total resection, and the progression rate increased proportionally with increasing delay from surgery to RT. Conclusions: Delayed RT is associated with a higher rate of local and metastatic disease

  11. Incidence Patterns and Trends of non-Central Nervous System Solid Tumours in Children and Adolescents. A Collaborative Study of the Spanish Population Based Cancer Registries

    Science.gov (United States)

    Larrañaga, Nerea; Sanchez, Mª José; Ardanaz, Eva; Felipe, Saray; Marcos-Gragera, Rafael; Ramos, María; Carulla, Marià; Chirlaque, Mª Dolores; Argüelles, Marcial V.; Martos, Carmen; Mateo, Antonio; Peris-Bonet, Rafael

    2016-01-01

    Objective: To describe incidence patterns and trends in children (0-14 years) and adolescents (15-19 age-range) with solid tumours, except those of central nervous system (CNS), in Spain. Methods: Cases were drawn from eleven Spanish population-based cancer registries. Incidence was estimated for the period 1983-2007 and trends were evaluated using Joinpoint regression analysis. Results: The studied tumour groups accounted for 36% of total childhood cancers and 47.6% of those diagnosed in adolescence with annual rates per million of 53.5 and 89.3 respectively. In children 0 to 14 years of age, Neuroblastoma (NB) was the commonest (7.8%) followed by Soft-tissue sarcomas (STS) (6.3%), bone tumours (BT) (6.2%) and renal tumours (RT) (4.5%). NB was the most frequently diagnosed tumour before the 5th birthday, while STS and BT were the commonest at 5-9 years of age, and BT and Carcinoma and other epithelial tumours (COET) at 10-14. COET presented the highest incidence in adolescents, followed by germ-cell tumours (GCT), BT and STS. These four diagnostic groups accounted for 94% of total non-CNS solid tumours, in adolescents. Overall incidence rates increased significantly in children up to 1996 with an annual percentage change (APC) of 2.6% (95%CI: 1.7; 3.6). NB and COET showed significant time trend (APCs: 1.4% and 3.8% respectively) while other tumour groups such as RT, STS, BT or GCT had no significant changes over time. A significant increase was present in NB under the age of 5 and in BT and STS in children aged 10-14 years. In adolescents there were significant increases for all tumours combined (APC=2.7; 95%CI: 1.8-3.6) and for STS, GCT and COET (APCs: 3.2%, 4.4% and 3.5% respectively), while other tumour groups such as hepatic tumours, BT or thyroid carcinomas showed a decreasing trend or no increase. Conclusions: Overall, the incidence of the studied cancers in children increased along the period 1983-1996 with no posterior significant rise, while the incidence

  12. Sequencing of Local Therapy Affects the Pattern of Treatment Failure and Survival in Children With Atypical Teratoid Rhabdoid Tumors of the Central Nervous System

    Energy Technology Data Exchange (ETDEWEB)

    Pai Panandiker, Atmaram S., E-mail: atmaram.pai-panandiker@stjude.org [Department of Radiological Sciences, St. Jude Children' s Research Hospital, Memphis, TN (United States); Merchant, Thomas E.; Beltran, Chris [Department of Radiological Sciences, St. Jude Children' s Research Hospital, Memphis, TN (United States); Wu, Shengjie [Department of Biostatistics, St. Jude Children' s Research Hospital, Memphis, TN (United States); Sharma, Shelly [Department of Radiological Sciences, St. Jude Children' s Research Hospital, Memphis, TN (United States); Boop, Frederick A. [Department of Surgery, St. Jude Children' s Research Hospital, Memphis, TN (United States); Jenkins, Jesse J. [Department of Pathology, St. Jude Children' s Research Hospital, Memphis, TN (United States); Helton, Kathleen J. [Department of Radiological Sciences, St. Jude Children' s Research Hospital, Memphis, TN (United States); Wright, Karen D.; Broniscer, Alberto [Department of Oncology, St. Jude Children' s Research Hospital, Memphis, TN (United States); Kun, Larry E. [Department of Radiological Sciences, St. Jude Children' s Research Hospital, Memphis, TN (United States); Gajjar, Amar [Department of Oncology, St. Jude Children' s Research Hospital, Memphis, TN (United States)

    2012-04-01

    Purpose: To assess the pattern of treatment failure associated with current therapeutic paradigms for childhood atypical teratoid rhabdoid tumors (AT/RT). Methods and Materials: Pediatric patients with AT/RT of the central nervous system treated at our institution between 1987 and 2007 were retrospectively evaluated. Overall survival (OS), progression-free survival, and cumulative incidence of local failure were correlated with age, sex, tumor location, extent of disease, and extent of surgical resection. Radiotherapy (RT) sequencing, chemotherapy, dose, timing, and volume administered after resection were also evaluated. Results: Thirty-one patients at a median age of 2.3 years at diagnosis (range, 0.45-16.87 years) were enrolled into protocols that included risk- and age-stratified RT. Craniospinal irradiation with focal tumor bed boost (median dose, 54 Gy) was administered to 18 patients. Gross total resection was achieved in 16. Ten patients presented with metastases at diagnosis. RT was delayed more than 3 months in 20 patients and between 1 and 3 months in 4; 7 patients received immediate postoperative irradiation preceding high-dose alkylator-based chemotherapy. At a median follow-up of 48 months, the cumulative incidence of local treatment failure was 37.5% {+-} 9%; progression-free survival was 33.2% {+-} 10%; and OS was 53.5% {+-} 10%. Children receiving delayed RT ({>=}1 month postoperatively) were more likely to experience local failure (hazard ratio [HR] 1.23, p = 0.007); the development of distant metastases before RT increased the risk of progression (HR 3.49, p = 0.006); and any evidence of disease progressionbefore RT decreased OS (HR 20.78, p = 0.004). Disease progression occurred in 52% (11/21) of children with initially localized tumors who underwent gross total resection, and the progression rate increased proportionally with increasing delay from surgery to RT. Conclusions: Delayed RT is associated with a higher rate of local and metastatic

  13. NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation

    OpenAIRE

    Serrander, Lena; Cartier, Laetitia; Bedard, Karen; Banfi, Botond; Lardy, Bernard; Plastre, Olivier; Sienkiewicz, Andrzej; Fórró, Laszló; Schlegel, Werner; Krause, Karl-Heinz

    2007-01-01

    Abstract NOX4 is an enigmatic member of the NOX family of ROS-generating NADPH oxidases. NOX4 has a wide tissue distribution, but the physiological function and activation mechanisms are largely unknown, and its pharmacology poorly understood. We have generated cell lines expressing NOX4 upon tetracycline induction. Tetracycline induced a rapid increase in NOX4 mRNA (1h) followed closely (2h) by a release of reactive oxygen species (ROS). Upon tetracycline withdrawal, NOX4 mRNA lev...

  14. Automatic Code Generation for Recurring Code Patterns in Web Based Applications and Increasing Efficiency of Data Access Code

    OpenAIRE

    Senthil, J; Arumugam, S.; S Margret Anouncia; Abhinav Kapoor

    2012-01-01

    Today, a lot of web applications and web sites are data driven. These web applications have all the static and dynamic data stored in relational databases. The aim of this thesis is to generate automatic code for data access located in relational databases in minimum time.

  15. Discovery of a Metal-Poor Field Giant with a Globular Cluster Second-Generation Abundance Pattern

    OpenAIRE

    Fernandez-Trincado, J. G.; Robin, A. C.; Moreno, E; Schiavon, R. P.; Peréz, A. E. García; Vieira, K.; Cunha, K.; Zamora, O.; Sneden, C.; Carrera, R.; Johnson, J.A.; Shetrone, M.; Zasowski, G.; García-Hernándes, D. A.; Majewski, S. R.

    2016-01-01

    We report on the direct detection from observations obtained with the APOGEE survey of a metal-poor ([Fe/H]$=-1.3$) field giant star in the Milky Way, with an extreme Mg-Al abundance ([Mg/Fe]$=$-0.31; [Al/Fe]$=$1.49) seen only among the secondary population of globular clusters. This star, 2M16011638-1201525 found using SDSSIII/APOGEE data also shows particularly atypical light-element patterns not seen among Galactic disk field stars, indicating that it could have been born in a globular clu...

  16. Conventional and intelligent generalized supervisory control for combined cycle generating power stations.; Control supervisiorio generalizado convencional e inteligente para centrales de generacion de ciclo combinado

    Energy Technology Data Exchange (ETDEWEB)

    Martinez M, Miguel A; Sanchez P, Marino [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico); Gonzalez Rubio S, Jose L [Cento Nacional de Investigacion y Desarrollo Tecnologico (Cenidet), Cuernavaca, Morelos (Mexico)

    2005-07-01

    Under the expectations of expansion of electric power generation in Mexico, this work exposes the development of a conventional and intelligent generalized supervisory control (CSG) for a combined cycle generation power plant. This one allows to obtain the optimal operation of the power plant through the automatic starting of the generating units and to obtain the maximum possible amount of electrical power in automatic and safe form. For the development of the CSG a control loop by temperature was implemented for the gas turbine system and a control loop by strangled pressure for the gas turbine and a control loop by strangled pressure for the steam turbine. The design of these supervisory systems was made with base in the critical limits on the involved variables of the process: blading average temperature, for the gas turbine (GT) and strangled pressure for the steam turbine (ST) [Spanish] Bajo estas expectativas de expansion de generacion de energia en Mexico, este trabajo expone el desarrollo de un control supervisorio generalizado (CSG) para una central generacion de ciclo combinado. Este permite lograr la operacion optima de la planta a traves del arranque automatico de las unidades generadoras y obtener la maxima cantidad posible de potencia electrica en forma automatica y segura. Para el desarrollo del CSG se implanto un lazo de control por temperatura para el sistema de turbina de gas y un lazo de control por presion estrangulada para la turbina de gas y un lazo de control por presion estrangulada para la turbina de vapor. El diseno de estos sistemas supervisorio se realizo con base en los limites criticos de las variables del proceso involucradas: temperatura promedio de empaletado para la turbina de gas (TG) y presion estrangulada para la turbina de vapor (TV)

  17. Next generation sequencing (NGS) database for tandem repeats with multiple pattern 2°-shaft multicore string matching

    OpenAIRE

    Chinta Someswara Rao; Viswanadha Raju, S.

    2016-01-01

    Next generation sequencing (NGS) technologies have been rapidly applied in biomedical and biological research in recent years. To provide the comprehensive NGS resource for the research, in this paper , we have considered 10 loci/codi/repeats TAGA, TCAT, GAAT, AGAT, AGAA, GATA, TATC, CTTT, TCTG and TCTA. Then we developed the NGS Tandem Repeat Database (TandemRepeatDB) for all the chromosomes of Homo sapiens, Callithrix jacchus, Chlorocebus sabaeus, Gorilla gorilla, Macaca fascicularis, Macac...

  18. Academic Generations and Academic Work: Patterns of Attitudes, Behaviors and Research Productivity of Polish Academics after 1989

    OpenAIRE

    Kwiek, Marek

    2015-01-01

    This paper focuses on a generational change taking place in the Polish academic profession: a change in behaviors and attitudes between two groups of academics. One was socialized to academia under the communist regime (1945-1989) and the other entered the profession in the post-1989 transition period. Academics of all age groups are beginning to learn how tough the competition for research funding is, but young academics (“academics under 40”), being the target of recent policy initiat...

  19. On Centralized Fuel Purchasing of Power Generating Utilities%试论发电集团燃料的集中采购

    Institute of Scientific and Technical Information of China (English)

    李飞

    2014-01-01

    由于煤碳资源限制、交通运输制约和供需格局不均衡等原因,使得发电集团的燃料采购长期实行分散采购模式。这种模式存在着管控力度弱、短期行为多,采购范围小,成本高,且不利监督约制等一系列的问题。随着市场经济的发展,外部市场给集中采购营造了良好的环境,而且集中采购可以整合采购资源,降低成本,也有利于加强集团管控力度,规范采购行为,因此,实行集中采购是必要的也是可行的。%Due to the resource control of coal, limitation of transportation and uneven supply-demand distribu-tion, etc., power generating utilities have been practicing separate purchasing for long time.This mode has defi-ciency in terms of weak control, many short-term behaviors, small purchase scope, high cost and inconvenience of monitoring.As the market economy develops, external market provides a good environment for centralized purcha-sing, which can integrate resources, lower costs, enhance management and regulate purchasing behaviors.Thus it is imperative to implement centralized purchasing.

  20. Generalized conventional and intelligent supervisory control system for combined cycle generation power plants; Sistema de control supervisorio generalizado convencional e inteligente para centrales de generacion de ciclo combinado

    Energy Technology Data Exchange (ETDEWEB)

    Martinez Morales, Miguel Angel

    2004-12-15

    (conventional or intelligent) is possible to get more power generation than if we use the automatic methods based on feedback MW control. Consequently, the financial benefit due to the MW generated along a period of 2 months, is equivalent to return the investment required if the CCPP would had been repowered. Test also showed that with the fuzzy based SGC is possible to get a 'little more' power generation than if we use the PID based SGC. The development and implementation of the SGC was made in three phases: First Phase: Upgrading of the simulation dynamic mathematical model and implementation in a new software platform based on LabWindows/CVI. Second Phase: Design, implementation and testing of the PID based SGC. Third Phase: Design and implementation and testing of the Intelligent SGC, based in fuzzy logic. [Spanish] El programa de obras de generacion de la Comision Federal de Electricidad (CFE) del ano 2004 al ano 2008 esta caracterizado por el dominio del proceso de ciclo combinado para la expansion de generacion de energia en Mexico [CFE, 2000]. De acuerdo con los datos presentados por esta fuente, el incremento estimado en la capacidad de generacion de potencia electrica es de 12876 MW, de los cuales las centrales de ciclo combinado aportaran 10655 MW, lo que representa el 82.75%. Bajo estas expectativas de expansion de generacion de energia en Mexico, en este trabajo de tesis se desarrollo un sistema de control supervisorio generalizado (CSG) convencional (PID) e inteligente (logica difusa) para una central de generacion de ciclo combinado, el cual permite lograr la operacion optima de la planta a traves del arranque automatico de las unidades generadoras y obtener la maxima cantidad posible de potencia electrica en forma automatica y segura. Para el desarrollo del CSG se implanto un lazo de control por temperatura para el sistema de turbina de gas (TG) y un lazo de control por presion estrangulada para la turbina de vapor (TV). El diseno de estos sistemas

  1. Generation of Domestic Hot Water, Space Heating and Driving Pattern Profiles for Integration Analysis of Active Loads in Low Voltage Grids

    DEFF Research Database (Denmark)

    Diaz de Cerio Mendaza, Iker; Pigazo, Alberto; Bak-Jensen, Birgitte;

    2013-01-01

    household level. Despite of the well-known flexible service that this kind of loads can provide, their flexibility is highly dependent of the domestic hot water and space heating demand and the driving habits of each user. This paper presents two methodologies employed to randomly generate thermal power...... demand and electric vehicle driving profiles, to be used for power grid calculations. The generated thermal profiles relied on a statistical analysis made from real domestic hot water and space heating data from 25 households of a typical Danish residential area. The driving profiles instead were formed...... based on conclusions derived from previous analysis on Danish driving patterns and the driving cycles extracted from the European project ARTEMIS. The obtained random profiles will allow electrical networks in Denmark to be analyzed while maintaining the probability of the original data set....

  2. Air mass patterns and temporal variation of the isotopic composition of atmospheric water vapour and precipitation over Central Turkey and groundwater recharge

    International Nuclear Information System (INIS)

    Full text: Water vapour and event precipitation have been collected within the program of coordinated research project about isotopic composition of precipitation in the Mediterranean basin in relation to air circulation patterns and climate at Ankara since January 2001. The purpose of this study is the determination of the interaction between climate conditions, chemical composition and isotopic composition (δ18O, δ2H) of precipitation and water vapor in Turkey. For this purpose we have been collecting samples at Ankara station to understand the variation of daily/event and seasonal isotopic values of precipitation and water vapor. The study focuses on the systematic collection of basic data on isotope content of precipitation and water vapor in Ankara, Turkey to determine temporal variations of environmental isotopes in precipitation and consequently to provide basic isotopic data for the use of environmental isotopes in hydrological investigations within the scope of water resources inventory, planning and development. Sampling of rain water and water vapor have been carried out in Ankara Turkey, from January 2001 to December 2001, by means of a pluviometer, water vapor sampling system respectively. The relation between the isotopic composition of precipitation and synoptic parameters is examined. The rain samples can be separated into three group based on 'deuterium excess' for year 2001 and long term observation of Ankara, Antalya and Adana stations of Turkey. The majority of the samples have a 'deuterium excess' between 10 and 22 per mille and other has values less than 10 per mille and greater than 22. The rains with a 'deuterium excess' of more than 22 per mille, between 10 and 22 and less than 10 are associated with air masses which comes from East Mediterranean (SW), North Atlantic (N, NW) and Central Atlantic (W, SW) respectively. Although it is not possible to derive the isotopic composition of the water vapor from isotopic composition of

  3. Levels and patterns of polycyclic aromatic hydrocarbons in fly ash generated in Coal-fired power plant

    International Nuclear Information System (INIS)

    The burning of pulverized coal to produce energy for generation of electricity in thermal power plants results in huge quantity of coal ash of varying properties. Because of the increase in electricity production, the amount of ash produced will increase proportionally. A large percentage of coal fly ash is comprised of relatively inert materials, such as silica and other trace and toxic elements. The coal ash also contain organic constituents of potential environmental concern. So far, very few studies on characterization of organic constituents in fly ash have been reported in the literature. In the present study, the fly ashes generated from the power stations are investigated regarding the distribution of 14 PAHs. The total amount of PAHs in the fly ash samples varied between 45.8 ng/g and 257.7 ng/g. Lower molecular weight (MW) PAHs, were found to be predominant in the fly ash samples. The concentration of Benzo(a)pyrene, which is the most potent carcinogenic PAH was found to vary between 0.8 ng/g to 6.3 ng/g with a mean concentration of 2.5 ng/g. (author)

  4. Discovery of a Metal-Poor Field Giant with a Globular Cluster Second-Generation Abundance Pattern

    CERN Document Server

    Fernandez-Trincado, J G; Moreno, E; Schiavon, R P; Peréz, A E García; Vieira, K; Cunha, K; Zamora, O; Sneden, C; Carrera, R; Johnson, J A; Shetrone, M; Zasowski, G; García-Hernándes, D A; Majewski, S R; Reylé, C; Blanco-Cuaresma, S; Martinez-Medina, L A; Pérez-Villegas, A; Valenzuela, O; Pichardo, B; Meza, A; Mészáros, Sz; Sobeck, J; Geisler, D; Anders, F; Schultheis, M; Tang, B; Roman-Lopes, A; Mennickent, R E; Pan, K; Nitschelm, C; Allard, F

    2016-01-01

    We report on the direct detection from observations obtained with the APOGEE survey of a metal-poor ([Fe/H]$=-1.3$) field giant star in the Milky Way, with an extreme Mg-Al abundance ([Mg/Fe]$=$-0.31; [Al/Fe]$=$1.49) seen only among the secondary population of globular clusters. This star, 2M16011638-1201525 found using SDSSIII/APOGEE data also shows particularly atypical light-element patterns not seen among Galactic disk field stars, indicating that it could have been born in a globular cluster. We explore several explanations, in particular studying the orbit of the star to check the probability of it being related to known globular clusters. With the use of a Monte Carlo scheme, we performed simple orbital integrations assuming the estimated distance of 2M16011638-1201525 and the available six-dimensional phase-space coordinates of 63 globular clusters, looking for close encounters in the past with a minimum distance approach within the tidal radius for each cluster. We found a very low probability that 2...

  5. Effect of the electric field pattern on the generation of fast electrons in front of lower hybrid launchers

    Energy Technology Data Exchange (ETDEWEB)

    Valade, Laurent, E-mail: laurent.valade@cea.fr; Ekedahl, Annika; Colas, Laurent; Goniche, Marc; Hillairet, Julien [CEA, IRFM, F-13108 Saint Paul-lez-Durance (France); Fuchs, Vladimir; Petrzilka, Vaclav [Institute of Plasma Physics, AS CR, Prague (Czech Republic); Li, Miaohui; Zhang, Bin [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China)

    2015-12-10

    The effect of the detailed waveguide spectrum on the electron acceleration has been studied for the 3.7 GHz LHCD launchers in Tore Supra, i.e. the ITER-like passive-active multijunction (PAM) launcher and the fully-active-multijunction (FAM) launcher, using test electron modelling technique. The detailed launched antenna wave spectrum is used as input to the code that computes the dynamics of the electrons in the electric field. Comparison with the LHCD launchers in EAST, operating at 2.45 GHz and 4.6 GHz, has also been made. The simulations show that the PAM-design generates lower flux of fast electrons than FAM-launchers, this could be the consequence of the wider waveguide of PAM-launcher (14.65 mm for Tore-Supra) than FAM-launcher (8 mm for Tore-Supra)

  6. Linear energy transfer and track pattern recognition of secondary radiation generated in hadron therapy beam in a PMMA target

    International Nuclear Information System (INIS)

    Hadron therapy uses ion beams for irradiation of cancerous tissue taking advantage of the highly localized dose deposition in the target tumor. For a correct estimation of dose deposited in tissue surrounding the target it is necessary to consider also the contribution of energetic secondary radiation generated by primary ions. It was already experimentally demonstrated that this contribution can be measured using the semiconductor pixel detector Timepix (256 × 256 pixels with 55 μm pitch) visualizing traces of secondary particles. The resolving power of the detector enables the differentiation of traces of different types of particles. In this work we studied the possibilities of determination of different types of secondary particles in correlation with their flight direction. Such identification allows correct assignment of dose for each type of particle. The distribution of secondary particles was compared to Monte Carlo simulations. Measurements were performed with a PMMA target irradiated with a therapeutic carbon beam at the Heidelberg Ion-Beam Therapy Center (HIT).

  7. Patterns of landscape evolution on the central and northern Tibetan Plateau investigated using in-situ produced 10Be concentrations from river sediments

    Science.gov (United States)

    Li, Yingkui; Li, Dewen; Liu, Gengnian; Harbor, Jon; Caffee, Marc; Stroeven, Arjen P.

    2014-07-01

    Quantifying long-term erosion rates across the Tibetan Plateau and its bordering mountains is of critical importance to an understanding of the interaction between climate, tectonic movement, and landscape evolution. We present a new dataset of basin-wide erosion rates from the central and northern Tibetan Plateau derived using in-situ produced 10Be concentrations of river sediments. Basin-wide erosion rates from the central plateau range from 10.1±0.9 to 36.8±3.2 mm/kyr, slightly higher than published local erosion rates measured from bedrock surfaces. These values indicate that long-term downwearing of plateau surfaces proceeds at low rates and that the landscape is demonstrably stable in the central plateau. In contrast, basin-wide erosion rates from the Kunlun Shan on the northern Tibetan Plateau range from 19.9±1.7 to 163.2±15.9 mm/kyr. Although the erosion rates of many of these basins are much higher than the rates from the central plateau, they are lower than published basin-wide erosion rates from other mountains fringing the Tibetan Plateau, probably because the basins in the Kunlun Shan include both areas of low-relief plateau surface and high-relief mountain catchments and may also result from retarded fluvial sediment transport in an arid climate. Significantly higher basin-wide erosion rates derived from the Tibetan Plateau margin, compared to the central plateau, reflect a relatively stable plateau surface that is being dissected at its margins by active fluvial erosion.

  8. Mortality pattern of the surrounding population of the Central Nuclear Almirante Alvaro Alberto / 1986 to 2007; Padrao da mortalidade da populacao circunvizinha a Central Nuclear Almirante Alvaro Alberto / 1986 a 2007

    Energy Technology Data Exchange (ETDEWEB)

    Leite, Teresa Cristina Sampaio de Barros; Silva, Ilson Peixoto Medeiros da; Jannuzzi, Denise Maria Souza; Higino, Thiago Nunes; Santos, Tatiana Rodrigues dos [Fundacao Eletronuclear de Assistencia Medica (CIRA/FEAM), Angra dos Reis, RJ (Brazil). Centro de Informacoes sobre Radioepidemiologia; Xavier, Diego Ricardo [Fundacao Inst. Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, RJ (Brazil). lnst. de Comunicacao e Informacao Cientifica e Tecnologica; Silva, Roseli Monteiro da [Fundacao Inst. Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, RJ (Brazil)

    2011-05-15

    This paper aims to update two earlier epidemiological studies on the mortality profile of the resident population in the influence area of the Central Nuclear Almirante Alvaro Alberto. The main objective is analyze and compare the profile of mortality among the population classified in areas with the distance from source of exposure in three strata. Municipalities contained within a radius of 30 km of the nuclear power, neighboring municipalities, contained within a radius of 30 to 50 km, municipalities contained within 50 to 100 km, beyond Cabo Frio, which presents similar characteristics to the municipality of Angra dos Reis

  9. Paleomagnetism of the Gran Sasso range salient (central Apennines, Italy): Pattern of orogenic rotations due to translation of a massive carbonate indenter

    OpenAIRE

    Satolli, S.; Dipartimento di Scienze della Terra, Università di Chieti, Chieti, Italy; Speranza, F.; Istituto Nazionale di Geofisica e Vulcanologia, Sezione Roma2, Roma, Italia; Calamita, F.; Dipartimento di Scienze della Terra, Università di Chieti, Chieti, Italy

    2005-01-01

    We report on the paleomagnetism (39 new sites) of Gran Sasso, an indenter-controlled salient of the external central Apennines formed by two orthogonal limbs. We find that Gran Sasso is a complex salient, paleomagnetically corresponding to neither a nonrotating nor an oroclinal end-member. Data from the core of the arc show that the indenter itself did not undergo any rotation. Conversely, rotations of variable magnitude and sign are observed along the curveshaped thrust fronts. Rotatio...

  10. A generative inference framework for analysing patterns of cultural change in sparse population data with evidence for fashion trends in LBK culture.

    Science.gov (United States)

    Kandler, Anne; Shennan, Stephen

    2015-12-01

    Cultural change can be quantified by temporal changes in frequency of different cultural artefacts and it is a central question to identify what underlying cultural transmission processes could have caused the observed frequency changes. Observed changes, however, often describe the dynamics in samples of the population of artefacts, whereas transmission processes act on the whole population. Here we develop a modelling framework aimed at addressing this inference problem. To do so, we firstly generate population structures from which the observed sample could have been drawn randomly and then determine theoretical samples at a later time t2 produced under the assumption that changes in frequencies are caused by a specific transmission process. Thereby we also account for the potential effect of time-averaging processes in the generation of the observed sample. Subsequent statistical comparisons (e.g. using Bayesian inference) of the theoretical and observed samples at t2 can establish which processes could have produced the observed frequency data. In this way, we infer underlying transmission processes directly from available data without any equilibrium assumption. We apply this framework to a dataset describing pottery from settlements of some of the first farmers in Europe (the LBK culture) and conclude that the observed frequency dynamic of different types of decorated pottery is consistent with age-dependent selection, a preference for 'young' pottery types which is potentially indicative of fashion trends. PMID:26674195

  11. Next-generation sequencing of ABCA4: High frequency of complex alleles and novel mutations in patients with retinal dystrophies from Central Europe.

    Science.gov (United States)

    Ścieżyńska, Aneta; Oziębło, Dominika; Ambroziak, Anna M; Korwin, Magdalena; Szulborski, Kamil; Krawczyński, Maciej; Stawiński, Piotr; Szaflik, Jerzy; Szaflik, Jacek P; Płoski, Rafał; Ołdak, Monika

    2016-04-01

    Variation in the ABCA4 locus has emerged as the most prevalent cause of monogenic retinal diseases. The study aimed to discover causative ABCA4 mutations in a large but not previously investigated cohort with ABCA4-related diseases originating from Central Europe and to refine the genetic relevance of all identified variants based on population evidence. Comprehensive clinical studies were performed to identify patients with Stargardt disease (STGD, n = 76) and cone-rod dystrophy (CRD, n = 16). Next-generation sequencing targeting ABCA4 was applied for a widespread screening of the gene. The results were analyzed in the context of exome data from a corresponding population (n = 594) and other large genomic databases. Our data disprove the pathogenic status of p.V552I and provide more evidence against a causal role of four further ABCA4 variants as drivers of the phenotype under a recessive paradigm. The study identifies 12 novel potentially pathogenic mutations (four of them recurrent) and a novel complex allele p.[(R152*; V2050L)]. In one third (31/92) of our cohort we detected the p.[(L541P; A1038V)] complex allele, which represents an unusually high level of genetic homogeneity for ABCA4-related diseases. Causative ABCA4 mutations account for 79% of STGD and 31% of CRD cases. A combination of p.[(L541P; A1038V)] and/or a truncating ABCA4 mutation always resulted in an early disease onset. Identification of ABCA4 retinopathies provides a specific molecular diagnosis and justifies a prompt introduction of simple precautions that may slow disease progression. The comprehensive, population-specific study expands our knowledge on the genetic landscape of retinal diseases. PMID:26593885

  12. Permission of change of limits in the vapor generators of the Atucha I Nuclear Central; Permiso de cambio de limites en los GVs de la CNA-I

    Energy Technology Data Exchange (ETDEWEB)

    Ventura, M. [Autoridad Regulatoria Nuclear, Av. Libertador 8250 (1429), Capital Federal (Argentina)]. e-mail: mventura@sede.arn.gov.ar

    2006-07-01

    In the mark of the modification of the Atucha-I Nuclear Central Installation (CNA-I) as consequence of the Introduction of the System 'Second Drain of Heat' (SSC), the Entity Responsible for the CNA-I (NASA) requested authorization to the Nuclear Regulatory Authority (ARN) to modify the value of the minimum level of water in the secondary side in the Steam generators (GVs) to activate the signal 'shoot of the Cut of the Reactor' (RESA-LLV). As the level in the GVs is one of those parameters that are used to shoot the Emergency Feeding System (RX), component of the SSC System, also was analyzed the change in the activation of the shoot signal of the 'Second Drain of Heat' (2SSC-LLV). The ARN uses for the study of the nuclear safety of nuclear power plants, the series of prediction programs RELAP5/MOD3.X. It participates of the evaluation and maintenance activities of these codes through specific agreements with the U.S. Nuclear Regulatory Commission (US-NRC). It is necessary to account with programs of this type since the ARN it licenses the construction and operation of Nuclear Power Plants (NPPs) and other outstanding facilities and it inquires its operation according to its own standards. With these tools its are auditing the calculations that the Responsible Entities of the operation make to guarantee the operability of the NPPs assisting the mentioned standards. The analysis with computational codes is used as a tool to achieve the best understanding in the behavior of the plant in union with the engineering approach, the manual calculations, the data analysis and the experience in the operation of the machine. (Author)

  13. 基于Agent的小世界网络中集中式与分散式创新扩散仿真分析%Research on Simulation of Central and Dispersion Patterns Innovation Diffusion in Small World Network

    Institute of Scientific and Technical Information of China (English)

    严云峰; 李英

    2011-01-01

    An innovation diffusion model with the function of memory is used in the small world network to specify the difference of two diffusion patterns,which are the central pattern and the dispersion pattern.And the result of simulation shows that dispersion pattern is extremely better than the central one, which is reflected in effectiveness, less time, wider coverage and better works in innovation resist network.Further we find that the increase of "Innovation Perceive" can improve the diffusion effectively,cut off time for a node to diffuse in the early period and also which will avoid "Lock in".%在小世界网络中,采用节点具有记忆功能的创新扩散模型进行仿真实验,考察了两种不同的创新扩散方式--集中式扩散和分散式扩散在小世界网络中创新扩散效果的优劣.实验结果表明,在小世界网络中采用分散式扩散要比采用集中式扩散的效果好,具体体现在扩散的时间短、范围广,而且在创新抵触型网络中能更有效地进行扩散.同时更进一步发现,通过增加节点的"创新感知"能有效地改进节点在网络中的扩散效果,大大减少节点在扩散前期所花费的时间,使节点避免出现"Lock-in"现象.

  14. The precise temporal pattern of pre-hearing spontaneous activity is necessary for tonotopic map refinement

    OpenAIRE

    Clause, Amanda; Kim, Gunsoo; Sonntag, Mandy; Weisz, Catherine J.C.; Vetter, Douglas E.; Rübsamen, Rudolf; Kandler, Karl

    2014-01-01

    Patterned spontaneous activity is a hallmark of developing sensory systems. In the auditory system, rhythmic bursts of spontaneous activity are generated in cochlear hair cells and propagated along central auditory pathways. The role of these activity patterns in the development of central auditory circuits has remained speculative. Here we demonstrate that blocking efferent cholinergic neurotransmission to developing hair cells in mice that lack the α9 subunit of nicotinic acetylcholine rece...

  15. Multimodal function of the sweet taste receptor expressed in pancreatic β-cells: generation of diverse patterns of intracellular signals by sweet agonists.

    Science.gov (United States)

    Nakagawa, Yuko; Nagasawa, Masahiro; Mogami, Hideo; Lohse, Martin; Ninomiya, Yuzo; Kojima, Itaru

    2013-01-01

    The sweet taste receptor is expressed in the taste bud and is activated by numerous sweet molecules with diverse chemical structures. It is, however, not known whether these sweet agonists induce a similar cellular response in target cells. Using MIN6 cells, a pancreatic β-cell line expressing endogenous sweet taste receptor, we addressed this question by monitoring changes in cytoplasmic Ca2+ ([Ca2+]i) and cAMP ([cAMP]i) induced by four sweet taste receptor agonists. Glycyrrhizin evoked sustained elevation of [Ca2+]i but [cAMP]i was not affected. Conversely, an artificial sweetener saccharin induced sustained elevation of [cAMP]i but did not increase [Ca2+]i. In contrast, sucralose and acesulfame K induced rapid and sustained increases in both [Ca2+]i and [cAMP]i. Although the latter two sweeteners increased [Ca2+]i and [cAMP]i, their actions were not identical: [Ca2+]i response to sucralose but not acesulfame K was inhibited by gurmarin, an antagonist of the sweet taste receptor which blocks the gustducin-dependent pathway. In addition, [Ca2+]i response to acesulfame K but not to sucralose was resistant to a Gq inhibitor. These results indicate that four types of sweeteners activate the sweet taste receptor differently and generate distinct patterns of intracellular signals. The sweet taste receptor has amazing multimodal functions producing multiple patterns of intracellular signals. PMID:23933592

  16. Theoretical and computational analysis of second- and third-harmonic generation in periodically patterned graphene and transition-metal dichalcogenide monolayers

    Science.gov (United States)

    Weismann, Martin; Panoiu, Nicolae C.

    2016-07-01

    Remarkable optical and electrical properties of two-dimensional (2D) materials, such as graphene and transition-metal dichalcogenide (TMDC) monolayers, offer vast technological potential for novel and improved optoelectronic nanodevices, many of which rely on nonlinear optical effects in these 2D materials. This paper introduces a highly effective numerical method for efficient and accurate description of linear and nonlinear optical effects in nanostructured 2D materials embedded in periodic photonic structures containing regular three-dimensional (3D) optical materials, such as diffraction gratings and periodic metamaterials. The proposed method builds upon the rigorous coupled-wave analysis and incorporates the nonlinear optical response of 2D materials by means of modified electromagnetic boundary conditions. This allows one to reduce the mathematical framework of the numerical method to an inhomogeneous scattering matrix formalism, which makes it more accurate and efficient than previously used approaches. An overview of linear and nonlinear optical properties of graphene and TMDC monolayers is given and the various features of the corresponding optical spectra are explored numerically and discussed. To illustrate the versatility of our numerical method, we use it to investigate the linear and nonlinear multiresonant optical response of 2D-3D heteromaterials for enhanced and tunable second- and third-harmonic generation. In particular, by employing a structured 2D material optically coupled to a patterned slab waveguide, we study the interplay between geometric resonances associated to guiding modes of periodically patterned slab waveguides and plasmon or exciton resonances of 2D materials.

  17. Application of cluster analysis to surface ozone, NO₂ and SO₂ daily patterns in an industrial area in Central-Southern Spain measured with a DOAS system.

    Science.gov (United States)

    Adame, J A; Notario, A; Villanueva, F; Albaladejo, J

    2012-07-01

    The daily variations of surface ozone, NO₂ and SO₂ have been investigated in a heavily industrialised area in the centre of the Iberian Peninsula (Puertollano) using hourly values recorded during two years (2008-2009) with an active LP-DOAS system. The meteorological conditions and air masses have been studied using the HYSPLIT model. The maximum hourly levels of these air pollutants exceeded 100 ppb for ozone, 150 ppb for SO₂ and 210 ppb for NO₂. However, mean values for ozone, NO₂ and SO₂ were of 49, 10 and 3 ppb respectively. Daily-monthly evolutions (defined as daily evolutions for different months) have been analysed in order to know the general daily behaviour of these species. Air pollution problems have been identified using the thresholds defined in the European Directive 2008. The limits to protect human health (human health protection limitations) have been exceeded during the study period. In order to find a set of representative daily cycles for each pollutant at different air quality regimes, a K-mean cluster technique has been applied. Five and four optimal cluster numbers have been obtained for the daily patterns of ozone and SO₂ respectively. In addition, we studied the daily variation of the temperature, relative and specific humidity and wind speed associated with each air pollutant daily pattern. Ozone daily patterns showed typical daily variations with one exception of a cluster which presents a peak in the early morning. For SO₂, the first two clusters present a low mixing ratio, however cluster 3 and 4 are less frequent but with higher levels. The more frequent air pollutant daily patterns do not exceed the threshold defined in the Directive. Nevertheless, clusters with lower frequency (representing between 5 and 7% of days) exceed the thresholds and could be considered as air pollution events. PMID:22591990

  18. Patterns and Determinants of International Fragmentation of Production. Evidence from Outward Processing Trade between the EU and the Countries of Central-Eastern Europe

    OpenAIRE

    Salvatore Baldone; Fabio Sdogati; Lucia Tajoli

    1999-01-01

    Both theoretical and applied research have benne devoting much attention to the fact that large and growing shares of international trade floes among industrialized countries consist of intermediate goods. The new configuration of the productive structure underlying such phenomenon has been named ‘internationally fragmented’. In this paper we investigate patterns giving rise to international trade for reasons of processing. Data on textile and apparel trade between major EU countries and sic ...

  19. Analyzing the impact of rural housing credits on indices of physical development and housing patterns (Case study: villages in the central part of the city of Kashmar

    Directory of Open Access Journals (Sweden)

    Javad Bazrafshan

    2015-06-01

    Full Text Available Giving credit to the villages for physical development and strengthening housing is one of the strategies and programs implemented in rural areas that to some extent, it has caused the empowerment of villages. Some facility will be provided to villagers as the loans of the improvement of rural housing in Iran which have some restrictions and requirements according to infrastructure, materials, and plan of houses and these restrictions and requirements of these houses will distinct them from the traditional rural housing. The goal of this research is the Analyzing the impact of rural housing credits on indices of physical development and housing patterns. The method of the research is analytic-descriptive and the documentary and field methods are used for collecting data. The results show that the dimension of the impact of housing credit on physical development has the maximum effect on the index of the change of rural architecture pattern and in the dimension of housing credits on housing pattern; it has the maximum impact on the index of the type of housing.

  20. 财务公司模式下资金集中管理信息化研究%The Research on Fund Centralized Management Informatization based on the Pattern of Financial Company

    Institute of Scientific and Technical Information of China (English)

    唐忠良

    2015-01-01

    推进资金集中管理信息化是现代企业集团持续健康发展的必由之路。文章基于实务与理论界关于我国企业集团资金集中管理信息化研究的现状,对企业集团财务公司模式下如何实现资金集中管理信息化进行了研究。为了找出一条全面、可行的提升我国企业集团财务公司模式下资金集中管理信息化水平的路径,文章首先从总体框架与技术角度指出了资金集中管理信息化蓝图,并进一步从建设原则、六大功能模块、安全保障方面论述了如何构建资金集中管理信息化平台,最后提出了顺利推进企业集团资金集中管理信息化建设需要注意的因素。研究为我国企业集团通过信息化手段提升资金集中管理水平提供了思路,为我国企业集团从战略与实施层面构建立安全、高效、集成的资金集中管理信息化平台指明了方向。%Propelling fund centralized management informatization is the only way for sustained and healthy development of modern enterprise group. This article based on the practice and theory of enterprise group fund centralized management informatization currently , elaborates how to realize enterprise group fund centralized management informatization under the pattern of financial company. In order to find a comprehensive and viable way to enhance enterprise group fund centralized management informatization level under the pattern of financial company, this paper firstly points out a blueprint of fund centralized management informatization from overall framework and technical view, furthermore analyzes how to build a fund centralized management informatization platform which includes six function modules, security and other aspects, finally points out the factors of smoothly advances fund centralized management informatization. The research provides the ideas of enterprise group how to promote the level of fund centralized management by means