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Sample records for central neuraxial blockade-assisted

  1. Recent developments in paediatric neuraxial blocks

    Directory of Open Access Journals (Sweden)

    Vrushali Chandrashekhar Ponde

    2012-01-01

    Full Text Available Paediatric anaesthesia and paediatric regional anaesthesia are intertwined. Almost all surgeries unless contradicted could be and should be supplemented with a regional block. The main objective of this review is to elaborate on the recent advances of the central neuraxial blocks, such as application of ultrasound guidance and electrical stimulation in the pursuit of safety and an objective end point. This review also takes account of the traditional technique and understand the benefits as well the risk of each as compared with the recent technique. The recent trends in choosing the most appropriate peripheral block for a given surgery thereby sparing the central neuroaxis is considered. A penile block for circumcision or a sciatic block for unilateral foot surgery, rather than caudal epidural would have a better risk benefit equation. Readers will find a special mention on the recent thoughts on continuous epidural analgesia in paediatrics, especially its rise and fall, yet its unique importance. Lastly, the issue of block placements under sedation or general anaesthesia with its implication in this special population is dealt with. We conducted searches in MEDLINE (PubMed and assessed the relevance of the abstracts of citations identified from literature searches. The search was carried out in English, for last 10 years, with the following key words: Recent advances in paediatric regional anaesthesia; ultrasound guidance for central neuraxial blocks in children; role of electrical stimulation in neuraxial blocks in children; complications in neuraxial block. Full-text articles of potentially relevant abstracts were retrieved for further review.

  2. Neuraxial opioid-induced pruritus: a review.

    LENUS (Irish Health Repository)

    Szarvas, Szilvia

    2012-02-03

    When intrathecal and epidural opioids are administered, pruritus occurs as an unwanted and troublesome side effect. The reported incidence varies between 30% and 100%. The exact mechanisms of neuraxial opioid-induced pruritus remain unclear. Postulated mechanisms include the presence of an "itch center" in the central nervous system, medullary dorsal horn activation, and antagonism of inhibitory transmitters. The treatment of intrathecal opioid-induced pruritus remains a challenge. Many pharmacological therapies, including antihistamines, 5-HT(3)-receptor antagonists, opiate-antagonists, propofol, nonsteroid antiinflammatory drugs, and droperidol, have been studied. In this review, we will summarize pathophysiological and pharmacological advances that will improve understanding and ultimately the management of this troublesome problem.

  3. Back Pain and Neuraxial Anesthesia.

    Science.gov (United States)

    Benzon, Honorio T; Asher, Yogen G; Hartrick, Craig T

    2016-06-01

    The incidence of back pain after neuraxial anesthesia in the adult population is not different from that after general anesthesia. The pain is usually mild, localized in the low back, rarely radiates to the lower extremities, and has a duration of only a few days. The risk factors for development of back pain include the lithotomy position, multiple attempts at block placement, duration of surgery longer than 2.5 hours, body mass index ≥32 kg/m, and a history of back pain. However, there is no permanent worsening of preexisting back pain after neuraxial anesthesia. The back pain has been attributed to tears in the ligaments, fascia, or bone with localized bleeding; immobility of the spine; relaxation of the paraspinal muscles under anesthesia; flattening of the normal lumbar convexity; and stretching and straining of the lumbosacral ligaments and joint capsules. The addition of an anti-inflammatory drug to the local anesthetic used for skin infiltration may decrease the incidence and severity of back pain. The use of spinal or epidural anesthesia in the adult, non-obstetric and obstetric populations should depend on the advantages offered by the technique and not on the occurrence of back pain after the procedure. Additional studies are needed to confirm the efficacy of epidural dexamethasone, or other steroids, or the addition of an anti-inflammatory drug to the local anesthetic infiltration for the prevention of back pain after neuraxial anesthesia. Future studies should involve a physician with expertise in the evaluation of chronic low back pain to help identify the cause of the back pain and institute appropriate treatment(s). PMID:27195644

  4. The Effect of Neuraxial Anesthesia on Maternal Cerebral Hemodynamics

    NARCIS (Netherlands)

    Postma, Ineke R.; van Veen, Teelkien R.; Mears, Scott L.; Zeeman, Gerda G.; Haeri, Sina; Belfort, Michael A.

    2014-01-01

    Objective Neuraxial anesthesia is known to reduce sympathetic tone and mean arterial pressure. Effects on cerebral hemodynamics in pregnancy are not well known. We hypothesize that cerebral hemodynamic parameters will change with respect to baseline following regional analgesia/anesthesia. Study Des

  5. Neuraxial (epidural and intrathecal) opioids for intractable pain.

    Science.gov (United States)

    Farquhar-Smith, Paul; Chapman, Suzanne

    2012-02-01

    1. Neuraxial opioids are considered for use in patients who have resistant intractable pain that fails to respond to other treatment options or pain that responds to analgesia but for which the doses required result in unacceptable side-effects. 2. Neuraxial opiods can be considered for both chronic non-malignant pain and chronic cancer-related pain. 3. Effectiveness in chronic non-malignant pain and cancer pain is exerted through the use of either single-agent drugs (opioids) or a combination of drugs: opioids, local anaesthetics and other drugs such as clonodine and ziconotide. 4. Complications of long-term continuous infusion therapy are related to the insertion process (haematoma), the mechanical device (both pump and catheter) and the long-term effects of the drugs. 5. Patients will require ongoing ambulatory monitoring and supportive care. PMID:26516463

  6. Risk Factors for and Prediction of a Difficult Neuraxial Block

    DEFF Research Database (Denmark)

    Stendell, Line; Lundstrøm, Lars H; Wetterslev, Jørn;

    2015-01-01

    BACKGROUND: A difficult neuraxial block (DNB) may be associated with complications. The aims of this study were to estimate the prevalence of DNB, assess patient-related and organizational factors associated with DNB, and evaluate the diagnostic accuracy of an accumulated risk score for predicting...... DNB. METHODS: A consecutive cohort of 73,579 patients was retrieved. A predefined DNB score and information on patient-related and organizational factors were included in the analyses. Logistic regression analysis was performed. We evaluated the diagnostic accuracy of an accumulated weighted point...... score of the patient-related risk factors of DNB. RESULTS: The prevalence of DNB and abandoned neuraxial block was 3.9 (95% confidence interval [95% CI], 3.7-4.0) and 0.2 (95% CI, 0.16-0.22), respectively. Body mass index of 35 or higher and previous DNB were associated with DNB, with 3.23 (95% CI, 2...

  7. Imaging features of calcifying pseudoneoplasms of the neuraxis

    International Nuclear Information System (INIS)

    Objective: To identify the imaging characteristics of calcifying pseudoneoplasms of the neuraxis (CAPNON) and do literature review. Methods: Five patients of pathologically-proved CAPNON underwent preoperative MR examination,among which 4 underwent CT scan, 2 underwent DSA examination and 1 underwent SPECT. All imaging data were retrospectively analyzed with the emphasis on imaging characteristics.Results Five patients of CAPNON with the diameter of 1.5 to 5.0 cm were found in five patients (Male 4; Female 1; age 25 to 60 years old). Three lesions were located in the skull base, one was located in the cervical spine and one in the foramen magnum and upper cervical segment. All patients underwent MRI examination and 4 of them also took CT scanning. On plain CT, all lesions showed obvious calcification. On T1WI all masses showed hypointensity, and on T2WI 4 of the lesions showed iso- or hypointensity and 1 heterogeneous signal intensity. On contrast-enhanced MR images, peripheral enhancement was demonstrated in 3 lesions, homogeneous enhancement was found in case and one lesion showed no enhancement. The pathologic analysis indicated that inside the lesions were abundant calcification, fibroepithelial tissue and mucoid matrix and no edema was detected around the lesions. Conclusions: CAPNON displayed the predilection to male adults and the neuraxis was the predilection site. Calcification on CT images, hypointensity on MR images and peripheral enhancement will be helpful for the diagnosis of CAPNON, but the final confirmation still needs the pathologic results. (authors)

  8. Self-reported post-discharge symptoms following obstetric neuraxial blockade.

    LENUS (Irish Health Repository)

    Hayes, N E

    2010-10-01

    Economic pressures are leading to earlier hospital discharge following delivery, before complications of obstetric neuraxial block may become apparent. Our aim was to estimate the incidence of symptoms presenting post-discharge at a single tertiary obstetric centre.

  9. The evidence of neuraxial administration of analgesics for cancer-related pain

    DEFF Research Database (Denmark)

    Kurita, G P; Benthien, K S; Nordly, M;

    2015-01-01

    clinical and methodological diversity that precluded a meta-analysis. They also presented several limitations, which reduced study internal validity. However, they demonstrated better pain control for all interventions analysed. Side effects were described, but there were few significant differences...... related to cancer, pain, neuraxial route, analgesic and side effects. The search was performed in PubMed, EMBASE, and Cochrane for the period until February 2014. Studies were analysed according to methods, results, quality of evidence, and strength of recommendation. RESULTS: The number of abstracts...

  10. Neuraxial and peripheral nerve blocks in patients taking anticoagulant or thromboprophylactic drugs: challenges and solutions

    Directory of Open Access Journals (Sweden)

    Li J

    2015-08-01

    Full Text Available Jinlei Li, Thomas Halaszynski Department of Anesthesiology, Yale University, Yale New Haven Hospital, New Haven, CT, USA Abstract: Incidence of hemorrhagic complications from neuraxial blockade is unknown, but classically cited as 1 in 150,000 epidurals and 1 in 220,000 spinals. However, recent literature and epidemiologic data suggest that for certain patient populations the frequency is higher (1 in 3,000. Due to safety concerns of bleeding risk, guidelines and recommendations have been designed to reduce patient morbidity/mortality during regional anesthesia. Data from evidence-based reviews, clinical series and case reports, collaborative experience of experts, and pharmacology used in developing consensus statements are unable to address all patient comorbidities and are not able to guarantee specific outcomes. No laboratory model identifies patients at risk, and rarity of neuraxial hematoma defies prospective randomized study so “patient-specific” factors and “surgery-related” issues should be considered to improve patient-oriented outcomes. Details of advanced age, older females, trauma patients, spinal cord and vertebral column abnormalities, organ function compromise, presence of underlying coagulopathy, traumatic or difficult needle placement, as well as indwelling catheter(s during anticoagulation pose risks for significant bleeding. Therefore, balancing between thromboembolism, bleeding risk, and introduction of more potent antithrombotic medications in combination with regional anesthesia has resulted in a need for more than “consensus statements” to safely manage regional interventions during anticoagulant/thromboprophylactic therapy. Keywords: antithrombotics, novel oral anticoagulant, regional, neurologic dysfunction, hematoma, peripheral nerve blockade

  11. Central neuraxial anaesthesia presenting with spinal myoclonus in the perioperative period: a case series

    Directory of Open Access Journals (Sweden)

    Bamgbade Olumuyiwa A

    2009-06-01

    Full Text Available Abstract Introduction Perioperative spinal myoclonus is extremely rare. Many anaesthetists and perioperative practitioners may not diagnose or manage this complication appropriately when it occurs. This case report of unusual acute spinal myoclonus following regional anaesthesia highlights certain aspects of this rare complication that have not previously been published. Case presentations A series of four consecutive patients who developed acute lower-limb myoclonus following spinal or epidural anaesthesia are described. The case series occurred at three different hospitals and involved four anaesthetists over a 3-year period. Two Caucasian men, aged 90-years-old and 67-years-old, manifested unilateral myoclonus. Two Caucasian women, aged 64-years-old and 53-years-old, developed bilateral myoclonus. Myoclonus was self-limiting in one patient, treated with further regional anaesthesia in one patient and treated with intravenous midazolam in two patients. The overall outcome was good in all patients, with no recurrence or sequelae in any of the patients. Conclusion This case series emphasizes that spinal myoclonus following regional anaesthesia is rare, has diverse pathophysiology and can have diverse presentations. The treatment of perioperative spinal myoclonus should be directed at the aetiology. Anaesthetists and perioperative practitioners who are unfamiliar with this rare complication should be reassured that it may be treated successfully with midazolam.

  12. Metachronous multifocal desmoid-type fibromatoses along the neuraxis with adenomatous polyposis syndrome.

    Science.gov (United States)

    Chung, K H Carlos; Charlton, Amanda; Arbuckle, Susan; Chaseling, Raymond; Owler, Brian K

    2010-10-01

    Desmoid-type fibromatosis, aggressive fibromatosis, or desmoid tumor is an uncommon benign but locally aggressive fibroblastic lesion. Although intraabdominal desmoid-type fibromatoses are well described in association with adenomatous polyposis syndrome, their occurrence along the neuraxis is extremely rare. The authors report the case of a 14-year-old boy with metachronous intracranial and spinal desmoid-type fibromatoses with preceding medulloblastoma. He was ultimately diagnosed with adenomatous polyposis syndrome. This is the first reported case of spinal desmoid-type fibromatosis in association with adenomatous polyposis syndrome. The identification of an underlying genetic instability allows for screening to detect lesions and institute measures to avoid preventable mortality from nonneurological tumors.

  13. Survey of pain specialists regarding conversion of high-dose intravenous to neuraxial opioids

    Science.gov (United States)

    Gorlin, Andrew W; Rosenfeld, David M; Maloney, Jillian; Wie, Christopher S; McGarvey, Johnathan; Trentman, Terrence L

    2016-01-01

    The conversion of high-dose intravenous (IV) opioids to an equianalgesic epidural (EP) or intrathecal (IT) dose is a common clinical dilemma for which there is little evidence to guide practice. Expert opinion varies, though a 100 IV:10:EP:1 IT conversion ratio is commonly cited in the literature, especially for morphine. In this study, the authors surveyed 724 pain specialists to elucidate the ratios that respondents apply to convert high-dose IV morphine, hydromorphone, and fentanyl to both EP and IT routes. Eighty-three respondents completed the survey. Conversion ratios were calculated and entered into graphical scatter plots. The data suggest that there is wide variation in how pain specialists convert high-dose IV opioids to EP and IT routes. The 100 IV:10 EP:1 IT ratio was the most common answer of survey respondent, especially for morphine, though also for hydromorphone and fentanyl. Furthermore, more respondents applied a more aggressive conversion strategy for hydromorphone and fentanyl, likely reflecting less spinal selectivity of those opioids compared with morphine. The authors conclude that there is little consensus on this issue and suggest that in the absence of better data, a conservative approach to opioid conversion between IV and neuraxial routes is warranted. PMID:27703394

  14. Optimal point of insertion of the needle in neuraxial blockade using a midline approach: study in a geometrical model

    Science.gov (United States)

    Vogt, Mark; van Gerwen, Dennis J; van den Dobbelsteen, John J; Hagenaars, Martin

    2016-01-01

    Performance of neuraxial blockade using a midline approach can be technically difficult. It is therefore important to optimize factors that are under the influence of the clinician performing the procedure. One of these factors might be the chosen point of insertion of the needle. Surprisingly few data exist on where between the tips of two adjacent spinous processes the needle should be introduced. A geometrical model was adopted to gain more insight into this issue. Spinous processes were represented by parallelograms. The length, the steepness relative to the skin, and the distance between the parallelograms were varied. The influence of the chosen point of insertion of the needle on the range of angles at which the epidural and subarachnoid space could be reached was studied. The optimal point of insertion was defined as the point where this range is the widest. The geometrical model clearly demonstrated, that the range of angles at which the epidural or subarachnoid space can be reached, is dependent on the point of insertion between the tips of the adjacent spinous processes. The steeper the spinous processes run, the more cranial the point of insertion should be. Assuming that the model is representative for patients, the performance of neuraxial blockade using a midline approach might be improved by choosing the optimal point of insertion.

  15. Progress of mechanisms and treatment regimens of neuraxial opioid-induced pruritus%椎管内注射阿片类药物所致瘙痒的发生机制及治疗研究进展

    Institute of Scientific and Technical Information of China (English)

    张静; 刘秀兰; 上官王宁

    2013-01-01

    背景 瘙痒是椎管内阿片类药物镇痛的常见并发症,其机制尚不完全清楚,阿片受体和非阿片受体都起到一定作用,中枢性μ阿片受体可能是其主要机制.椎管内阿片类药物所致的瘙痒常规抗组胺治疗无效,阿片受体拮抗药纳洛酮效果明确,但因逆转镇痛效果而限制了它的广泛应用.其他治疗药物如κ-阿片受体激动剂、5-羟色胺受体拮抗剂、多巴胺受体拮抗剂、丙泊酚及非甾体类抗炎药等可以不同程度地减轻阿片类药物引起的瘙痒,但其有效性存在争议. 目的 探讨阿片类药物诱发瘙痒的可能机制,进一步研究和探索新的治疗方法. 内容 就近年来阿片类药物诱发瘙痒的发生机制及目前存在的治疗方案进行综述. 趋向 最近鉴别出的瘙痒特异性μ1D阿片受体(μ1D-opioid receptor,MOR1D)为椎管内阿片类物质所致瘙痒的治疗提供了新的思路.%Background Pruritus is a common side-effect of intrathecal opiate analgesia and the pathogenesis of neuraxial opioid-induced pruritus is still unclear,which may be opioid receptor-induced or non-opioid receptor-induced,the central μ-opioid receptor may play the key role.The traditional antihistamines are ineffective for neuraxial opioid-induced pruritus.Opioid antagonists seem to be the most potent antipruritus drugs.Due to reversing analgesia,there are limitations for their wide use.Other drugs for itch such as κ-opioid receptor agonist,serotonin (5-HT3) receptor antagonist,dopamine (D2) receptor antagonist,propofol and nonsteroidal anti-inflammatory drugs have been tried.But their effectiveness is controversial.Objective To investigate the pathogenesis of neuraxial opioid-induced pruritus and to seek new treatments.Content This article reviewed literatures relating the mechanism and treatment of neuraxial opioid-induced pruritus.Trend Now the μ-opioid receptor isoform μ1D-opioid receptor (MOR1D) has been reported to be essential for

  16. [Ultrasound-assisted neuraxial anesthesia in a patient with previous lumbar laminectomy and fusion: a case report].

    Science.gov (United States)

    Geng, J; Li, M

    2016-02-18

    A patient with previous L3-4 posterior lumbar interbody fusion, pedicle screws instrumentation and L3-4 decompression, was scheduled for left total hip arthroplasty. Two years ago, due to poor landmarks palpation, the patient experienced a failed lumbar puncture after multiple attempts before herniorrhaphy. His plain radiography showed bilateral partial laminectomy at L3-4 level, and between L3 and L4, two posterior pedicle screws connected by metal rods on both sides. This time, we used ultrasound to locate L4-5 interlaminar space in paramedian sagittal oblique view and identified the spine midline by transverse interlaminar view before puncture. According to this information, L4-5 puncture point was verified and the combined spinal-epidural anesthesia was performed in a paramedian approach. After withdrawing clear cerebral spinal fluid, 15 mg hyperbaric bupivicaine was injected into intrathecal space. An epidural catheter was then inserted into the epidural space. The sensory block level was fixed at T10 to S within 10 minutes. Intraoperatively, the patient received 10 mL 2% (mass fraction) lidocaine through the epidural catheter in total. The surgery was uneventful. No neurologic complication was observed after the surgery. This case report demonstrates that ultRASound imaging can provide useful information for neuraxial needle placement and can be a valuable tool in managing patients with anatomical change around the spine. PMID:27538165

  17. Risk of Chronic Low Back Pain Among Parturients Who Undergo Cesarean Delivery With Neuraxial Anesthesia: A Nationwide Population-Based Retrospective Cohort Study.

    Science.gov (United States)

    Chia, Yuan-Yi; Lo, Yuan; Chen, Yan-Bo; Liu, Chun-Peng; Huang, Wei-Chun; Wen, Chun-Hsien

    2016-04-01

    To investigate the risk of chronic low back pain (LBP) in parturients undergoing cesarean delivery (CD) with neuraxial anesthesia (NA). LBP is common during pregnancy and also after delivery, but its etiology is poorly understood. Previous studies that investigated the correlation between epidural labor analgesia and chronic low back pain were inconclusive. These studies lacked objective diagnostic criteria for LBP and did not exclude possible confounders. We performed this nationwide population-based retrospective cohort study to explore the relationship between CD with NA and subsequent LBP. From the Taiwan National Health Insurance Research Database (NHIRD), we identified all primiparas who had given birth between January 1, 2000 and December 31, 2013. Using the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) procedure codes, we identified the women who had vaginal delivery (VD) and those who had CD. The mode of anesthesia was ascertained by the NHI codes. Multivariable logistic regression was used to estimate the odds of postpartum LBP in women undergoing CD with NA compared with those having VD. The outcome was a diagnosis of LBP according to the first ICD-9-CM diagnosis code. The patients were observed for 3 years after delivery or until diagnosis of postpartum LBP, withdrawal from the NHI system, death, or December 31, 2013. Of the 61,027 primiparas who underwent delivery during the observation period, 40,057 were eligible for inclusion in the study. Of these women, 27,097 (67.6%) received VD, 8662 (21.6%) received CD with spinal anesthesia, and 4298 (10.7%) received CD with epidural anesthesia (EA). Women who received CD with EA were found to have higher risk of LBP than did women who received VD, with the adjusted OR being 1.26 (95% CI: 1.17-1.34). CD with EA might increase the risk of subsequent chronic LBP.

  18. Neuraxial opioids in geriatrics: A dose reduction study of local anesthetic with addition of sufentanil in lower limb surgery for elderly patients

    Directory of Open Access Journals (Sweden)

    Sumit Kumar

    2011-01-01

    Full Text Available Background and Objectives: Neuraxial anesthesia in the elderly is associated with exaggerated responses to conventional doses of local anesthetics, thereby increasing the incidence of hemodynamic complications. A double-blind prospective study was carried out in our institute with an aim to compare the hemodynamic stability and quality of the conventional dose of hyperbaric bupivacaine (LA with low dose of LA and sufentanil in elderly patients scheduled for lower limb surgery, randomized to receive combined spinal epidural anesthesia. Methods: A total of 50 elderly patients of ASA grade I and II, divided randomly into groups I and II, of either sex undergoing lower limb surgery under combined spinal epidural anesthesia at our institute attached to a Government Medical College were enrolled for study. Group I received 2.5 ml of intrathecal hyperbaric bupivacaine (LA, while group II received 1.5 ml of intrathecal LA+0.1 ml sufentanil (5 μg. Both initial and postoperative subarachnoid block characteristics, hemodynamic and respiratory parameters, duration of analgesia, and side effects were observed and recorded. Statistical analysis was carried out using Chi-square and paired t test. Results: Demographic profile was comparable in both groups. Group I had a greater incidence of hypotension and, consequently, higher use of vasopressors (P<0.05. Onset of sensory analgesia, time to achieve peak sensory level, and recovery from motor blockade were significantly earlier in group II (P<0.05. Postoperative consumption of LA through epidural route was significantly higher in group I (P<0.05. The side effect profile was similar, except for a significantly higher incidence of shivering in group I (P<0.05. Conclusions: The study established that the dose of a local anesthetic can be safely and significantly lowered by 40%, with addition of low-dose sufentanil, thereby avoiding the hemodynamic fluctuation and providing a stable perioperative and postoperative

  19. Primary Diffuse Large B-Cell Lymphoma of Central Nervous System: Is Still Surgery an Unorthodox Treatment?

    OpenAIRE

    Siasios, Ioannis; Fotiadou, Aggeliki; Fotakopoulos, George; Ioannou, Maria; Anagnostopoulos, Vassilios; FOUNTAS, KONSTANTINOS

    2015-01-01

    Primary central nervous system lymphoma (PCNSL) is characterized as an extra-nodal non-Hodgkin lymphoma which develops from the neuraxis. The purpose was to report a case of a patient with a supra-tentorial tumor who underwent subtotal resection of his tumor as his biopsy was not indicative of a PCNSL tumor and had uneventful recovery until his last follow-up. A 42-year-old man was admitted to our department for generalized epileptic seizures. CT and MRI examinations revealed a tumor in his r...

  20. Ultrasound-assisted neuraxial anesthesia in a patient with previous lumbar laminecto-my and fusion:a case report%超声引导椎管内麻醉用于椎板切除内固定术后1例报道

    Institute of Scientific and Technical Information of China (English)

    耿姣; 李民

    2016-01-01

    SUMMARY A patient with previous L3 -4 posterior lumbar interbody fusion,pedicle screws instrumen-tation and L3 -4 decompression,was scheduled for left total hip arthroplasty.Two years ago,due to poor landmarks palpation,the patient experienced a failed lumbar puncture after multiple attempts before her-niorrhaphy.His plain radiography showed bilateral partial laminectomy at L3 -4 level,and between L3 and L4,two posterior pedicle screws connected by metal rods on both sides.This time,we used ultra-sound to locate L4 -5 interlaminar space in paramedian sagittal oblique view and identified the spine midline by transverse interlaminar view before puncture.According to this information,L4 -5 puncture point was verified and the combined spinal-epidural anesthesia was performed in a paramedian approach. After withdrawing clear cerebral spinal fluid,15 mg hyperbaric bupivicaine was injected into intrathecal space.An epidural catheter was then inserted into the epidural space.The sensory block level was fixed at T10 to S within 10 minutes.Intraoperatively,the patient received 10 mL 2% (mass fraction)lido-caine through the epidural catheter in total.The surgery was uneventful.No neurologic complication was observed after the surgery.This case report demonstrates that ultRASound imaging can provide useful in-formation for neuraxial needle placement and can be a valuable tool in managing patients with anatomical change around the spine.

  1. central t

    Directory of Open Access Journals (Sweden)

    Manuel R. Piña Monarrez

    2007-01-01

    Full Text Available Dado que la Regresión Ridge (RR, es una estimación sesgada que parte de la solución de la regresión de Mínimos Cuadrados (MC, es vital establecer las condiciones para las que la distribución central t de Student que se utiliza en la prueba de hipótesis en MC, sea también aplicable a la regresión RR. La prueba de este importante resultado se presenta en este artículo.

  2. Primary Diffuse Large B-Cell Lymphoma of Central Nervous System: Is Still Surgery an Unorthodox Treatment?

    Science.gov (United States)

    Siasios, Ioannis; Fotiadou, Aggeliki; Fotakopoulos, George; Ioannou, Maria; Anagnostopoulos, Vassilios; Fountas, Konstantinos

    2015-12-01

    Primary central nervous system lymphoma (PCNSL) is characterized as an extra-nodal non-Hodgkin lymphoma which develops from the neuraxis. The purpose was to report a case of a patient with a supra-tentorial tumor who underwent subtotal resection of his tumor as his biopsy was not indicative of a PCNSL tumor and had uneventful recovery until his last follow-up. A 42-year-old man was admitted to our department for generalized epileptic seizures. CT and MRI examinations revealed a tumor in his right parietal-occipital lobe that was surrounded by edema and was enhancing after gadolinium administration. The patient underwent a navigation-assisted parieto-occipital craniotomy and posterior parietal transcortical approach for tumor biopsy which was not indicative of PCNSL tumor. The surgical team decided to remove the tumor on site. Histological analysis of the resected specimen showed primary diffuse large B-cell lymphoma. Combined chemotherapy and radiation therapy was applied to the patient, and at his last follow-up (16 months), he is tumor free. In our case as in several other studies during the last decade, the outcome after the surgical resection of a PCNSL tumor in combination to radiation and chemotherapy was unexpectedly good. The role of surgery probably should be reconsidered for single lesion PCNSL tumors. PMID:26566417

  3. Actualizaciones en el manejo clínico de los opioides espinales en el dolor agudo postoperatorio Up to date in clinical management of neuraxial opioids for the treatment of postoperative pain

    Directory of Open Access Journals (Sweden)

    B. Mugabure Bujedo

    2012-04-01

    -200 μg.Opioids are the strongest drugs currently used for the treatment of pain. Over the last 40 years, because of the discovery of the spinal cord opioid receptors, the use of spinal opioids has become a standard for producing intense segmental analgesia without side effects associated with systemic administration. There is a widespread misconception that any opioid administered epidurally or intrathecally will always produce analgesia by a selective mechanism without central adverse effects. This is simply not true because multiple of these opioids produce analgesia by uptake into the systemic circulation or cerebrospinal fluid (CSF, with subsequent redistribution to brain opioid receptors. The findings indicate that increasing lipid solubility decreases the spinal cord bioavailability, therefore morphine is the most spinally selective opioid currently used in the epidural and intrathecal spaces. Extended release epidural morphine (EREM utilizes a proprietary liposomal carrier to provide prolonged analgesia without the need for an indwelling catheter. Fentanyl is the best option for ambulatory surgery and it becomes apparent that epidural fentanyl acts predominantly spinally when administered as a bolus, and predominantly supraspinally as a continuous infusion. Epidural methadone and hydromorphone are valid alternatives for improve analgesia in the postoperative setting. All opioids injected intrathecally can be expected to produce analgesia, at last in part, by a spinal mechanism. The principal difference among opioids is in their duration of analgesic action, speed of re-distribution and the mechanism by which the drug reaches brainstem sites. In general, lipophilic opioids produce short durations of action (1-4 hours, which makes them attractive for short-term postoperative states. However, morphine doses of only 100 to 200 μg produce potent analgesia lasting as long as 24 hours.

  4. Central Pain Syndrome

    Science.gov (United States)

    ... Enhancing Diversity Find People About NINDS NINDS Central Pain Syndrome Information Page Table of Contents (click to ... being done? Clinical Trials Organizations What is Central Pain Syndrome? Central pain syndrome is a neurological condition ...

  5. Central venous line - infants

    Science.gov (United States)

    CVL - infants; Central catheter - infants - surgically placed ... plastic tube that is put into a large vein in the chest. WHY IS A ... central catheter (PICC) or midline central catheter (MCC). A CVL ...

  6. To centralize or not to centralize?

    OpenAIRE

    Campbell, Andrew; Kunisch, Sven; Müller-Stewens, Günter

    2011-01-01

    The CEO's dilemma-were the gains of centralization worth the pain it could cause?-is a perennial one. Business leaders dating back at least to Alfred Sloan, who laid out GM's influential philosophy of decentralization in a series of memos during the 1920s, have recognized that badly judged centralization can stifle initiative, constrain the ability to tailor products and services locally, and burden business divisions with high costs and poor service.1 Insufficient centralization can deny bus...

  7. NIDDK Central Repository

    Data.gov (United States)

    U.S. Department of Health & Human Services — The NIDDK Central Repository stores biosamples, genetic and other data collected in designated NIDDK-funded clinical studies. The purpose of the NIDDK Central...

  8. Central and peripheral demyelination

    OpenAIRE

    Man Mohan Mehndiratta; Natasha Singh Gulati

    2014-01-01

    Several conditions cause damage to the inherently normal myelin of central nervous system, perepheral nervous system or both central and perepheral nervous system and hence termed as central demyelinating diseases, perepheral demyelinating diseases and combined central and perepheral demyelinating diseases respectively. Here we analysed and foccused on the etiology, prevalance, incidence and age of these demyelinating disorders. Clinical attention and various diagnostic tests are needed to ad...

  9. Distribution of transplanted human mesenchymal stem cells from Wharton’s Jelly in the central nervous systems of the EAE rats

    Directory of Open Access Journals (Sweden)

    Kovalchuk M. V.

    2015-10-01

    Full Text Available Human Wharton’s Jelly MSCs (hWJ-MSCs have a considerable advantage and potential in treating the central nervous system diseases and can be a new alternative treatment of Multiple Sclerosis (MS. Aim. To study the persistence and distribution of hWJ-MSCs along the neuraxis following transplantation in central nervous system of rats with experimental autoimmune encephalomyelitis (EAE, the animal model of MS. Methods. Isolation and cultivation of hWJ-MSCs in vitro. Immunological phenotyping by flow cytometry. EAE induction. Intrathecal (suboccipital injection of MSCs into CNS of SCH-induced EAE rats. Persistence of hWJ-MSCs in the CNS of hWJ-MSCs -treated rats was detected through detection of the human alpha-satellite DNA in the tissue sections and the cerebrospinal fluid (CSF by PCR at days 2, 3, 4 and 5 Results. PCR-assays for alpha-satellite sequences revealed that Human DNA was detected during 5 days following intrathecal injection at the peak of disease in the treated rats. It has been demonstrated that the human DNA was traced in CSF and various segments of a spinal cord. Conclusions. The data obtained suggest that intrathecally delivered hWJ-MSCs, with time, can migrate through the CSF from the injection site to various segments of CNS and persist therein during the first week of post transplantation, which was performed at the EAE disease peak in the xenogeneic setting without immunosuppression. hWJ-MSCs may be considered as a delivery cell source of therapeutic molecules for CNS inflammatory diseases.

  10. Central Laboratories Services

    Data.gov (United States)

    Federal Laboratory Consortium — The TVA Central Laboratories Services is a comprehensive technical support center, offering you a complete range of scientific, engineering, and technical services....

  11. Central centrifugal cicatricial alopecia

    OpenAIRE

    Collin Blattner; Dennis C Polley; Frank Ferritto; Elston, Dirk M

    2013-01-01

    Central centrifugal cicatricial alopecia is a common cause of progressive permanent apical alopecia. This unique form of alopecia includes entities previously know as “hot comb alopecia,” “follicular degeneration syndrome,” “pseudopelade” in African Americans and “central elliptical pseudopelade” in Caucasians. The etiology appears to be multifactorial and the condition occurs in all races.

  12. Optimal Central Bank Transparency

    NARCIS (Netherlands)

    van der Cruijsen, C.A.B.; Eijffinger, S.C.W.; Hoogduin, L.H.

    2008-01-01

    Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the opt

  13. Optimal central bank transparency

    NARCIS (Netherlands)

    C.A.B. van der Cruijsen; S.C.W. Eijffinger; L. Hoogduin

    2008-01-01

    Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the opt

  14. Optimal central bank transparency

    NARCIS (Netherlands)

    C.A.B. van der Cruijsen; S.C.W. Eijffinger; L.H. Hoogduin

    2010-01-01

    Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the opt

  15. Central pontine myelinolysis

    Science.gov (United States)

    ... from one nerve to another. The most common cause of central pontine myelinolysis is a quick change in the body's sodium ... The nerve damage caused by central pontine myelinolysis is usually ... The disorder can cause serious long-term (chronic) disability.

  16. Central Diffraction at ALICE

    CERN Document Server

    Lämsä, Jerry W

    2011-01-01

    The ALICE experiment is shown to be well suited for studies of exclusive final states from central diffractive reactions. The gluon-rich environment of the central system allows detailed QCD studies and searches for exotic meson states, such as glueballs, hybrids and new charmonium-like states. It would also provide a good testing ground for detailed studies of heavy quarkonia. Due to its central barrel performance, ALICE can accurately measure the low-mass central systems with good purity. The efficiency of the Forward Multiplicity Detector (FMD) and the Forward Shower Counter (FSC) system for detecting rapidity gaps is shown to be adequate for the proposed studies. With this detector arrangement, valuable new data can be obtained by tagging central diffractive processes.

  17. Central diffraction at ALICE

    Energy Technology Data Exchange (ETDEWEB)

    Laemsae, J W; Orava, R, E-mail: risto.orava@helsinki.fi [Helsinki Insitute of Physics, and Division of Elementary Particle Physics, Department of Physics, PL 64 (Gustaf Haellstroeminkatu 2a), FI-00014 University of Helsinki (Finland)

    2011-02-01

    The ALICE experiment is shown to be well suited for studies of exclusive final states from central diffractive reactions. The gluon-rich environment of the central system allows detailed QCD studies and searches for exotic meson states, such as glueballs, hybrids and new charmonium-like states. It would also provide a good testing ground for detailed studies of heavy quarkonia. Due to its central barrel performance, ALICE can accurately measure the low-mass central systems with good purity. The efficiency of the Forward Multiplicity Detector (FMD) and the Forward Shower Counter (FSC) system for detecting rapidity gaps is shown to be adequate for the proposed studies. With this detector arrangement, valuable new data can be obtained by tagging central diffractive processes.

  18. Organizational centralization in radiology.

    Science.gov (United States)

    Aas, I H Monrad

    2006-01-01

    Traditionally, hospitals have a radiology department, where images are taken and interpretation occurs. Teleradiology makes it possible to capture images in one location and transmit them elsewhere for interpretation. Organizational centralization of radiology interpretations is therefore of interest. Empirical data have been collected in qualitative interviews of 26 resource persons with substantial experience with picture archiving and communication systems and teleradiology, from 12 departments of radiology in Norway. The response rate was 90%. A total of 21 theoretically possible types of centralization of image interpretation were identified, representing combinations of three categories of geographical centralization, and seven categories of centralization according to function. Various advantages and disadvantages of centralization were identified. Organizational changes may be decisive for the future of teleradiology, but it may be wise to plan for change in small steps, since we know little about how broad future organizational changes based on teleradiology will be, or what will decide how far particular organizations will go. PMID:16438776

  19. Disseminated Hemangioblastomatosis of the Central Nervous System without von Hippel-Lindau Disease: A Case Report

    OpenAIRE

    Kim, Hong-Rae; Suh, Yeon-Lim; Kim, Jong-Won; Lee, Jung-Il

    2009-01-01

    We report a very rare case of hemangioblastomatosis that developed after surgical removal of a solitary cerebellar hemangioblastoma (HB). A 51-yr-old man presented with back pain 10 yr after undergoing surgery for cerebellar HB. Magnetic resonance imaging showed numerous mass lesions along the entire neuraxis accompanied by prominent leptomeningeal enhancement. Genomic DNA analysis showed no mutation in the von Hippel-Lindau (VHL) genes. A surgical specimen obtained from a lesion in the cauda...

  20. Imaging central pain syndromes.

    Science.gov (United States)

    Veldhuijzen, Dieuwke S; Greenspan, Joel D; Kim, Jong H; Coghill, Robert C; Treede, Rolf-Detlef; Ohara, Shinji; Lenz, Frederick A

    2007-06-01

    Anatomic, functional, and neurochemical imaging studies have provided new investigative tools in the study of central pain. High-resolution imaging studies allow for precise determination of lesion location, whereas functional neuroimaging studies measure pathophysiologic consequences of injury to the central nervous system. Additionally, magnetic resonance spectroscopy evaluates lesion-induced neurochemical changes in specific brain regions that may be related to central pain. The small number of studies to date precludes definitive conclusions, but the recent findings provide information that either supports or refutes current hypotheses and can serve to generate new ideas.

  1. Central nervous system

    Science.gov (United States)

    The central nervous system is composed of the brain and spinal cord. Your brain and spinal cord serve as the main "processing center" for your entire nervous system. They control all the workings of your body.

  2. Central Station Design Options

    DEFF Research Database (Denmark)

    2011-01-01

    The purpose of EDISON Work Package 4.1 is the evaluation of possible Central (charging) Stations design options for making possible the public charging of Electric Vehicles (EVs). A number of scenarios for EVs are assessed, with special emphasis on the options of Fast Charging and Battery Swapping....... The work identifies the architecture, sizing and siting of prospective Central Stations in Denmark, which can be located at shopping centers, large car parking lots or gas stations. Central Stations are planned to be integrated in the Danish distribution grid. The Danish island of Bornholm, where a high.......g. due to vandalism, the charge supply circuit is disconnected. More electrical vehicles on the market are capable today of quick charging up to 50 kW power level. The feasibility of Central Stations with fast charging/swapping option, their capacity, design, costs and grid impact, as well as battery...

  3. Central Data Exchange

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Central Data Exchange (CDX) enables fast, efficient and more accurate environmental data submissions from state and local governments, industry and tribes to...

  4. "Central Station" Londonis

    Index Scriptorium Estoniae

    2000-01-01

    Londoni galeriis Milch seitsme läti, leedu ja eesti kunstniku projekt "Central Station". Kuraatorid Lisa Panting, Sally Tallant. Eestist osalevad Hanno Soans (Catarina Campinoga koostöös valminud video), Kiwa, Kai Kaljo

  5. Central Asian Republic Info

    Data.gov (United States)

    US Agency for International Development — CAR Info is designed and managed by the Central Asian Republic Mission to fill in the knowledge and reporting gaps in existing agency systems for that Mission. It...

  6. Central nervous system resuscitation

    DEFF Research Database (Denmark)

    McIntosh, T K; Garde, E; Saatman, K E;

    1997-01-01

    Traumatic injury to the central nervous system induces delayed neuronal death, which may be mediated by acute and chronic neurochemical changes. Experimental identification of these injury mechanisms and elucidation of the neurochemical cascade following trauma may provide enhanced opportunities...

  7. Centralization and political accountability

    OpenAIRE

    Hindriks, Jean; Lockwood, Ben

    2004-01-01

    In this paper we abstract from the usual gains and costs of decentralization (e.g. preference matching, spillovers and economies of scale). Instead we compare the political accountability of decentralized governments relative to centralized ones when there is a risk of "bad" governance. We study both the selection and incentive effects of accountability. A key aspect of centralization is to make the politician answerable to multiple constituencies subject to a common budget constraint. Our ma...

  8. Central Bank independence

    OpenAIRE

    Vasile DEDU; Tiberiu STOICA

    2012-01-01

    In this paper we present the key aspects regarding central bank’s independence. Most economists consider that the factor which positively influences the efficiency of monetary policy measures is the high independence of the central bank. We determined that the National Bank of Romania (NBR) has a high degree of independence. NBR has both goal and instrument independence. We also consider that the hike of NBR’s independence played an important role in the significant disin...

  9. Outsourcing central banking

    DEFF Research Database (Denmark)

    Khoury, Sarkis Joseph; Wihlborg, Clas

    2005-01-01

    The literature on Currency Boards (CB) stops at the water edge in terms of dealing with the totality of the functions of a central bank. Monetary policy, and banking supervisioncan be "outsourced" in an open economy with substantial foreign direct investment (FDI)in the banking sector if political...... the feasibility of, and constraints on, outsourcing of central bank functions. A brief discussion of the Argentinian experience is used for contrast.Key words: Currency Board, Foreign Banks, Supervision, Regional Integration,outsourcing....

  10. CENTRAL PLATEAU REMEDIATION

    Energy Technology Data Exchange (ETDEWEB)

    ROMINE, L.D.

    2006-02-01

    A systematic approach to closure planning is being implemented at the Hanford Site's Central Plateau to help achieve the goal of closure by the year 2035. The overall objective of Central Plateau remediation is to protect human health and the environment from the significant quantity of contaminated material that resulted from decades of plutonium production in support of the nation's defense. This goal will be achieved either by removing contaminants or placing the residual contaminated materials in a secure configuration that minimizes further migration to the groundwater and reduces the potential for inadvertent intrusion into contaminated sites. The approach to Central Plateau cleanup used three key concepts--closure zones, closure elements, and closure process steps--to create an organized picture of actions required to complete remediation. These actions were merged with logic ties, constraints, and required resources to produce an integrated time-phased schedule and cost profile for Central Plateau closure. Programmatic risks associated with implementation of Central Plateau closure were identified and analyzed. Actions to mitigate the most significant risks are underway while high priority remediation projects continue to make progress.

  11. Colloquium on Central Asia

    International Nuclear Information System (INIS)

    This colloquium on Azerbaijan was organized by the direction of international relations of the French Senate and the French center of foreign trade (CFCE). This document gathers the interventions of the participants and the debates with the audience following these interventions. The topics treated concern: - the present day political-economical situation of Central Asia countries (problem of borders, relations with Russia and China); - the economies of Central Asia countries: short term problems and medium-term perspectives; - the relations with the European Union (political, economical, trade and investments, perspectives); - the European energy stakes of Caspian sea (oil and gas reserves, development of hydrocarbon resources, exploitation and transport constraints, stakes for Europe and France); - TotalFinaElf company in Central Asia (Kazakhstan, Azerbaijan, enclavement problem); - the economical impacts of the TRACECA pathway (Transport Corridor Europe Caucasus Asia). (J.S.)

  12. SOCRATES Invades Central Europe

    Directory of Open Access Journals (Sweden)

    Joseph Slowinski

    1998-04-01

    Full Text Available The objective of this article is to explore the current reality faced by higher education students in Central and Eastern Europe and to draw out the implications of this current reality for policy makers in the future. In the article, I explore the influence of transnational corporations' training programs on education as it currently pertains to Central and Eastern European higher education and employment. In addition, multinational corporate entities exercise influence on European Union policy through the role of lobby organizations and activities. I explore the influence of these practices on education with an emphasis on the emerging importance of Western language skills. In addition, I focus on the European Union and its efforts to expand into Central and Eastern Europe in order to provide a focal point for analysis.

  13. The Naive Central Banker

    Directory of Open Access Journals (Sweden)

    Marcelo de Carvalho Griebeler

    2015-09-01

    Full Text Available There has been in some countries a trend of assigning other functions to central banks besides price stability. The most suggested function to be added to monetary authority’s obligations is to pursue economic growth or full employment. In this paper we characterize the behavior and analyse the optimal monetary policy of, what we call, a naive central banker. We describe the naive behavior as one that does face the inflation-unemployment trade-off, but it tries to minimize both variables simultaneously. Our findings, both under discretion and commitment, indicate that the naive central banker delivers lower expected inflation and inflation variance than the benchmark behavior whenever the economy is rigid enough. However, the degree of conservativeness also affects this result, such that the less conservative the naive policymaker, the more rigidity is necessary.

  14. Hale Central Peak

    Science.gov (United States)

    2004-01-01

    19 September 2004 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows some of the mountains that make up the central peak region of Hale Crater, located near 35.8oS, 36.5oW. Dark, smooth-surfaced sand dunes are seen to be climbing up the mountainous slopes. The central peak of a crater consists of rock brought up during the impact from below the crater floor. This autumn image is illuminated from the upper left and covers an area approximately 3 km (1.9 mi) across.

  15. Central Bank independence

    Directory of Open Access Journals (Sweden)

    Vasile DEDU

    2012-08-01

    Full Text Available In this paper we present the key aspects regarding central bank’s independence. Most economists consider that the factor which positively influences the efficiency of monetary policy measures is the high independence of the central bank. We determined that the National Bank of Romania (NBR has a high degree of independence. NBR has both goal and instrument independence. We also consider that the hike of NBR’s independence played an important role in the significant disinflation process, as headline inflation dropped inside the targeted band of 3% ± 1 percentage point recently.

  16. Several Centuries of Centrality

    OpenAIRE

    Roth, Dana L.

    2015-01-01

    As Carolyn Bertozzi mentioned in her inaugural editorial, the relationship of “Central Science” to “Chemistry” became popularized over 40 years ago with the publication of the first edition of Brown and LeMay’s Chemistry: The Central Science, now in its 13th edition. Yet as late as 2003, Prof. Sason Shaik at The Hebrew University claimed “popularization of chemistry remains scant.” He goes on to share [his] “own experience of popularizing chemistry by delivering the following universal messag...

  17. ORIC central region calculations

    International Nuclear Information System (INIS)

    The central region for the K = 100 Oak Ridge Isochronous Cyclotron, ORIC, will be modified to provide better orbit centering, focusing of orbits in the axial direction, and phase selection, in order to improve extraction efficiency, and reduce radioactive activation of cyclotron components. The central region is specifically designed for the acceleration of intense light ion beams such as 60 MeV protons and 15--100 MeV alphas. These beams will be used in the production of radioactive atoms in the Radioactive Ion Beam Project at Oak Ridge National Laboratory

  18. Retiring the central executive.

    Science.gov (United States)

    Logie, Robert H

    2016-10-01

    Reasoning, problem solving, comprehension, learning and retrieval, inhibition, switching, updating, or multitasking are often referred to as higher cognition, thought to require control processes or the use of a central executive. However, the concept of an executive controller begs the question of what is controlling the controller and so on, leading to an infinite hierarchy of executives or "homunculi". In what is now a QJEP citation classic, Baddeley [Baddeley, A. D. (1996). Exploring the central executive. Quarterly Journal of Experimental Psychology, 49A, 5-28] referred to the concept of a central executive in cognition as a "conceptual ragbag" that acted as a placeholder umbrella term for aspects of cognition that are complex, were poorly understood at the time, and most likely involve several different cognitive functions working in concert. He suggested that with systematic empirical research, advances in understanding might progress sufficiently to allow the executive concept to be "sacked". This article offers an overview of the 1996 article and of some subsequent systematic research and argues that after two decades of research, there is sufficient advance in understanding to suggest that executive control might arise from the interaction among multiple different functions in cognition that use different, but overlapping, brain networks. The article concludes that the central executive concept might now be offered a dignified retirement.

  19. Ecodesign in Central America

    NARCIS (Netherlands)

    Crul, M.R.M.

    2003-01-01

    This PhD thesis describes and analyses the change process started by the Ecodesign project in Central America, executed between 1998 and 2002. The project started using the concept and praxis developed in Europe. Nine ecodesign projects were performed in industry, and ecodesign was introduced to cou

  20. Retiring the central executive.

    Science.gov (United States)

    Logie, Robert H

    2016-10-01

    Reasoning, problem solving, comprehension, learning and retrieval, inhibition, switching, updating, or multitasking are often referred to as higher cognition, thought to require control processes or the use of a central executive. However, the concept of an executive controller begs the question of what is controlling the controller and so on, leading to an infinite hierarchy of executives or "homunculi". In what is now a QJEP citation classic, Baddeley [Baddeley, A. D. (1996). Exploring the central executive. Quarterly Journal of Experimental Psychology, 49A, 5-28] referred to the concept of a central executive in cognition as a "conceptual ragbag" that acted as a placeholder umbrella term for aspects of cognition that are complex, were poorly understood at the time, and most likely involve several different cognitive functions working in concert. He suggested that with systematic empirical research, advances in understanding might progress sufficiently to allow the executive concept to be "sacked". This article offers an overview of the 1996 article and of some subsequent systematic research and argues that after two decades of research, there is sufficient advance in understanding to suggest that executive control might arise from the interaction among multiple different functions in cognition that use different, but overlapping, brain networks. The article concludes that the central executive concept might now be offered a dignified retirement. PMID:26821744

  1. Testing for central symmetry

    NARCIS (Netherlands)

    Einmahl, John; Gan, Zhuojiong

    2016-01-01

    Omnibus tests for central symmetry of a bivariate probability distribution are proposed. The test statistics compare empirical measures of opposite regions. Under rather weak conditions, we establish the asymptotic distribution of the test statistics under the null hypothesis; it follows that they a

  2. Central areolar choroidal dystrophy.

    NARCIS (Netherlands)

    Boon, C.J.F.; Klevering, B.J.; Cremers, F.P.M.; Zonneveld-Vrieling, M.N.; Theelen, T.; Hollander, A.I. den; Hoyng, C.B.

    2009-01-01

    OBJECTIVE: To describe the clinical characteristics, follow-up data and molecular genetic background in a large group of patients with central areolar choroidal dystrophy (CACD). DESIGN: Retrospective case series study. PARTICIPANTS: One hundred three patients with CACD from the Netherlands. METHODS

  3. Forward central jets correlations

    International Nuclear Information System (INIS)

    The azimuthal correlation between forward and central jets has been measured in pp collisions with the CMS detector at the LHC at the centre-of-mass energy of 7 TeV. The forward jet is required to be reconstructed in the hadronic forward calorimeter, within the pseudo-rapidity 3.2t>35 GeV. The measurement of the azimuthal angle between the jets is performed for different separations in pseudo-rapidity between the jets, with the largest separation being 7.5 units. The measurement is repeated for two subsamples of events, one in which an additional jet is required between the forward and the central jet, and one where the additional jet is vetoed. The measurement is compared to several different Monte Carlo models and tunes.

  4. Central simple Poisson algebras

    Institute of Scientific and Technical Information of China (English)

    SU; Yucai; XU; Xiaoping

    2004-01-01

    Poisson algebras are fundamental algebraic structures in physics and symplectic geometry. However, the structure theory of Poisson algebras has not been well developed. In this paper, we determine the structure of the central simple Poisson algebras related to locally finite derivations, over an algebraically closed field of characteristic zero.The Lie algebra structures of these Poisson algebras are in general not finitely-graded.

  5. FNAL central email systems

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Jack; Lilianstrom, Al; Pasetes, Ray; Hill, Kevin; /Fermilab

    2004-10-01

    The FNAL Email System is the primary point of entry for email destined for an employee or user at Fermilab. This centrally supported system is designed for reliability and availability. It uses multiple layers of protection to help ensure that: (1) SPAM messages are tagged properly; (2) All mail is inspected for viruses; and (3) Valid mail gets delivered. This system employs numerous redundant subsystems to accomplish these tasks.

  6. Measuring Central Bank Communication:

    OpenAIRE

    David Lucca; Francesco Trebbi

    2008-01-01

    We present a new automated, objective and intuitive scoring method to measure the content of central bank communication about future policy rate moves. We apply the methodology to statements released by the Federal Open Market Commitee (FOMC) after monetary policy meetings. Using high-frequency financial data, we find that yields on short-term risk-free nominal rates respond both to changes in policy rates and the content of the statements, whereas, medium and long-term rates only respond to ...

  7. Central nervous system diseases

    International Nuclear Information System (INIS)

    It is shown that roentgenological examination plays an important role in diagnosis of central nervous system diseases in children. The methods of roentgenological examinations are divided into 3 groups: roentgenography without contrast media (conventional roentgenography), roentgenography with artificial contrasting of liquor space (ventriculopneumoencelography, myelography) and contrasting of brain and spinal blood vessels (angiography). Conventional contrastless roentgenography of skull and vertebral column occupies leadership in diagnosis of brain neoplasms and some vascular diseases

  8. Centrally Banked Cryptocurrencies

    OpenAIRE

    Danezis, George; Meiklejohn, Sarah

    2015-01-01

    Current cryptocurrencies, starting with Bitcoin, build a decentralized blockchain-based transaction ledger, maintained through proofs-of-work that also generate a monetary supply. Such decentralization has benefits, such as independence from national political control, but also significant limitations in terms of scalability and computational cost. We introduce RSCoin, a cryptocurrency framework in which central banks maintain complete control over the monetary supply, but rely on a distribut...

  9. Centrally Banked Cryptocurrencies

    OpenAIRE

    Danezis, G.; Meiklejohn, S.

    2016-01-01

    Current cryptocurrencies, starting with Bitcoin, build a decentralized blockchain-based transaction ledger, maintained through proofs-of-work that also serve to generate a monetary supply. Such decentralization has benefits, such as independence from national political control, but also significant limitations in terms of computational costs and scalability. We introduce RSCoin, a cryptocurrency framework in which central banks maintain complete control over the monetary supply, but rely on...

  10. Centrality Measures in Networks

    CERN Document Server

    Bloch, Francis; Tebaldi, Pietro

    2016-01-01

    We show that although the prominent centrality measures in network analysis make use of different information about nodes' positions, they all process that information in an identical way: they all spring from a common family that are characterized by the same simple axioms. In particular, they are all based on a monotonic and additively separable treatment of a statistic that captures a node's position in the network.

  11. Central effects of fingolimod.

    Science.gov (United States)

    Cruz, Vítor T; Fonseca, Joaquim

    2014-08-01

    Introduccion. El fingolimod, un modulador del receptor de la esfingosina-1-fosfato (S1P) dotado de un mecanismo de accion novedoso, fue el primer tratamiento oral aprobado para la esclerosis multiple remitente recurrente. Su union a los receptores S1P1 de los linfocitos promueve la retencion selectiva de los linfocitos T virgenes y de memoria central en los tejidos linfoides secundarios, lo que impide su salida hacia el sistema nervioso central (SNC). Asimismo, el fingolimod atraviesa con facilidad la barrera hematoencefalica, y diversos estudios le atribuyen un efecto neuroprotector directo en el SNC. Objetivo. Revisar la informacion disponible acerca de los efectos centrales del fingolimod. Desarrollo. El desequilibrio entre los procesos lesivos y reparadores constituye un reflejo de la desmielinizacion cronica, la degeneracion axonal y la gliosis, y parece contribuir a la discapacidad que la esclerosis multiple acarrea. La facilidad con la que el fingolimod atraviesa la barrera hematoencefalica le permite actuar directamente sobre los receptores S1P localizados en las celulas del SNC. Una vez en el interior del SNC, ocupa los receptores S1P de los oligodendrocitos y de sus celulas precursoras, de los astrocitos, los microgliocitos y las neuronas, fomentando la remielinizacion, la neuroproteccion y los procesos endogenos de regeneracion. La eficacia evidenciada en los ensayos clinicos concuerda con un mecanismo de accion que incluiria efectos directos sobre las celulas del SNC. Conclusiones. Los datos disponibles indican que la eficacia del fingolimod en el tratamiento de la esclerosis multiple se debe a su ambivalencia como molecula inmunomoduladora y moduladora directa de los receptores S1P del SNC. Tanto es asi que estudios recientes le atribuyen efectos neuroprotectores en varios modelos que suscitan expectativas en torno a su posible aplicacion terapeutica en la enfermedad de Alzheimer, el paludismo cerebral y el neuroblastoma, asi como en la neuroproteccion

  12. [Central anticholinergic syndrome].

    Science.gov (United States)

    Fernández Urretavizcaya, P; Cenoz Osinaga, J C; Jáuregui Garía, M L; Gállego Culleré, J

    1991-10-01

    Two new cases of anticolinergic central syndrome are described. The first case, a 8 year old girl, suffered a severe encefalopathy after topical application of mydriatic cholirio as an aid in a rutine study of ocular refraction. The second case, 67 year old man presented a severe neurological picture after accidental intake of a silvester plantground (Atropa belladonna). His neurological condition returned quickly to normal whith administration of physostigmine. Differents aspects of the etiology, clinical picture and diagnosis are discussed with special emphasis in patients with delirium or acute confusional states. Finally, attention is drawn in the necessity of a properly use of anticholinergic drugs overcoat in aged or children.

  13. Flooding in Central Siberia

    Science.gov (United States)

    2002-01-01

    A mixture of snowmelt and ice jams in late May and June of this year caused the Taz River (left) and the Yenisey River (right) in central Siberia to overflow their banks. The flooding can be seen in this image taken on June 11, 2002, by the MODIS (Moderate Resolution Imaging Spectroradiometer) instrument aboard the Terra satellite. Normally, the rivers would resemble thin black lines in MODIS imagery. In the false-color images sage green and rusty orange is land, and water is black. Clouds are white and pink. Credit: Image courtesy Jacques Descloitres, MODIS Land Rapid Response Team at NASA GSFC

  14. Centralized vs. De-centralized Multinationals and Taxes

    DEFF Research Database (Denmark)

    Nielsen, Søren Bo; Raimondos-Møller, Pascalis; Schjelderup, Guttorm

    2005-01-01

    The paper examines how country tax differences affect a multinational enterprise's choice to centralize or de-centralize its decision structure. Within a simple model that emphasizes the multiple conflicting roles of transfer prices in MNEs - here, as a strategic pre-commitment device and a tax m...... manipulation instrument -, we show that (de-)centralized decisions are more profitable when tax differentials are (small) large.Keywords: Centralized vs. de-centralized decisions, taxes, MNEs.JEL-Classification: H25, F23, L23....

  15. en los pivotes centrales

    Directory of Open Access Journals (Sweden)

    Reynaldo Roque Rodés

    2005-01-01

    Full Text Available Se hace una revisión y comentarios sobre las ventajas y limitantes del empleo del LEPA (Low Enery Precision Aplication en los sistemas de riego de pivotes centrales. Estos sistemas o filosofía de manejo del agua para condiciones de escasez o mala calidad del líquido es una alternativa viable para la producción de alimentos. Introducida en la década del 80 en las planicies del sur de Texas, donde la alta evaporación del agua y la necesidad de regar grandes áreas con pivotes centrales obligaba a la búsqueda de una alternativa para incrementar al máximo la eficiencia de aplicación del riego. Aún en fase de estudio e introducción en Cuba para áreas específicas, puede ser una solución de incremento de los rendimientos de los cultivos, empleando menos agua y aguas con calidad limitada

  16. Central Sumatra enjoys success

    Energy Technology Data Exchange (ETDEWEB)

    Wongsosantiko, A.

    1977-05-02

    The Sihapas group contains the most prolific oil producing zones in the Central Sumatra Basin. It represents the transgressive, coarse clastic sequence deposited during the early Miocene. Some of these sandstone grade laterally into siltstones and shales of the Telisa Formation, believed to be a major source of rock for Central Sumatra oil. Recent exploratory wells drilled between the mountain front and coastal plain areas have provided more data for stratigraphic studies. These have resulted in subdivision of the lower Miocene transgressive sequence into discrete rock-stratigraphic units. The former Sihapas Formation has subsequently been elevated to group rank and now consists of several formations with the Duri Formation as the uppermost sand unit. This study covers Caltex's areas of operation, which includes the area between the Kampar River of the south, the Barumum River to the north, the Malacca Straits to the east, and the Barisan Mt. to the west. A basic map shows the regional scene, while a stratigraphic chart shows the lithology.

  17. Centrality Measures in Urban Networks

    CERN Document Server

    Crucitti, P; Porta, S; Crucitti, Paolo; Latora, Vito; Porta, Sergio

    2005-01-01

    Centrality has revealed crucial for understanding the structural order of complex relational networks. Centrality is also relevant for various spatial factors affecting human life and behaviors in cities. We present a comprehensive study of centrality distributions over geographic networks of urban streets. Four different measures of centrality, namely closeness, betweenness, straightness and information, are compared over eighteen 1-square-mile samples of different world cities. Samples are represented by primal geographic graphs, i.e. valued graphs defined by metric rather than topologic distance where intersections are turned into nodes and streets into edges. The spatial behavior of centrality indexes over the networks is investigated graphically by means of colour-coded maps. The results indicate that a spatial analysis, that we term Multiple Centrality Assessment(MCA), grounded not a single but on a set of different centrality indices, allows an extended comprehension of the city structure, nicely captu...

  18. Centralizer for well casing

    International Nuclear Information System (INIS)

    This patent describes an improved centralizer for centering a well casing in a wellbore. It comprises: a first anchor adapted to fit around and be securely fixed to the casing, the first anchor being threaded on its external surface; a first collar adapted to fit around and be threadedly engaged by the first anchor; a second collar adapted to fit around and free to rotate and move axially with respect to the casing; a second anchor adapted to fit around and be securely fixed to the casing spaced from the first anchor and comprising a bearing surface for restraining axial movement of the second collar along the casing; and metallic straps extending between the first collar and the second collar, and being securely fixed to each

  19. UA2 central calorimeter

    CERN Multimedia

    The UA2 central calorimeter measured the energy of individual particles created in proton-antiproton collisions. Accurate calibration allowed the W and Z masses to be measured with a precision of about 1%. The calorimeter had 24 slices like this one, each weighing 4 tons. The slices were arranged like orange segments around the collision point. Incoming particles produced showers of secondary particles in the layers of heavy material. These showers passed through the layers of plastic scintillator, generating light which was taken by light guides (green) to the data collection electronics. The amount of light was proportional to the energy of the original particle. The inner 23 cm of lead and plastic sandwiches measured electrons and photons; the outer 80 cm of iron and plastic sandwiches measured strongly interacting hadrons. The detector was calibrated by injecting light through optical fibres or by placing a radioactive source in the tube on the bottom edge.

  20. Central solar energy receiver

    Science.gov (United States)

    Drost, M. Kevin

    1983-01-01

    An improved tower-mounted central solar energy receiver for heating air drawn through the receiver by an induced draft fan. A number of vertically oriented, energy absorbing, fin-shaped slats are radially arranged in a number of concentric cylindrical arrays on top of the tower coaxially surrounding a pipe having air holes through which the fan draws air which is heated by the slats which receive the solar radiation from a heliostat field. A number of vertically oriented and wedge-shaped columns are radially arranged in a number of concentric cylindrical clusters surrounding the slat arrays. The columns have two mirror-reflecting sides to reflect radiation into the slat arrays and one energy absorbing side to reduce reradiation and reflection from the slat arrays.

  1. Flooding in Central China

    Science.gov (United States)

    2002-01-01

    During the summer of 2002, frequent, heavy rains gave rise to floods and landslides throughout China that have killed over 1,000 people and affected millions. This false-color image of the western Yangtze River and Dongting Lake in central China was acquired on August 21, 2002, by the Moderate-resolution Imaging Spectroradiometer (MODIS), flying aboard NASA's Terra spacecraft. (right) The latest flooding crisis in China centers on Dingtong Lake in the center of the image. Heavy rains have caused it to swell over its banks and swamp lakefront towns in the province of Hunan. As of August 23, 2002, more than 250,000 people have been evacuated, and over one million people have been brought in to fortify the dikes around the lake. Normally the lake would appear much smaller and more defined in the MODIS image. Credit: Image courtesy Jacques Descloitres, MODIS Land Rapid Response Team at NASA GSFC.

  2. UA1 central detector

    CERN Multimedia

    The UA1 central detector was crucial to understanding the complex topology of proton-antiproton events. It played a most important role in identifying a handful of Ws and Zs among billions of collisions. The detector was a 6-chamber cylindrical assembly 5.8 m long and 2.3 m in diameter, the largest imaging drift chamber of its day. It recorded the tracks of charged particles curving in a 0.7 Tesla magnetic field, measuring their momentum, the sign of their electric charge and their rate of energy loss (dE/dx). Atoms in the argon-ethane gas mixture filling the chambers were ionised by the passage of charged particles. The electrons which were released drifted along an electric field shaped by field wires and were collected on sense wires. The geometrical arrangement of the 17000 field wires and 6125 sense wires allowed a spectacular 3-D interactive display of reconstructed physics events to be produced.

  3. Hope for Central China

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The cities surrounding Changsha and Wuhan in the middle reaches of the Yangtze River will ally to form a new pilot zone to boost regional economic development China’s fourth pilot zone for compre- hensive and coordinated economic reform will soon debut in the middle reaches of the Yangtze River,open- ing a new area to attract foreign investment. The application has been submitted to the State Council for approval. The pilot zone will include two clusters of cities in central China:One consists of Wuhan,capital of Hubei Province,and eight surrounding cities in Hubei,and the other is composed of Changsha,Zhuzhou and Xiangtan,three major cities in Hunan Province.

  4. Sucker rod centralizer

    Energy Technology Data Exchange (ETDEWEB)

    Rivas, O.; Newski, A.

    1989-10-03

    This patent describes a device for centralizing at least one sucker rod within a production pipe downhole in a well and for reducing frictional forces between the pipe and at least one sucker rod. It comprises an elongate, substantially cylindrical body member having a longitudinal axis, a plurality of slots within the member and a rotatable member mounted within each slot, each of the plurality of slots has its major dimension along a first axis parallel to the longitudinal axis of the body member and is oriented with respect to the other seats so as to form a helicoidal array for maximizing the total surface contact area between the rotatable members and the pipe and for decreasing the forces acting on each rotatable member.

  5. [Central auditory prosthesis].

    Science.gov (United States)

    Lenarz, T; Lim, H; Joseph, G; Reuter, G; Lenarz, M

    2009-06-01

    Deaf patients with severe sensory hearing loss can benefit from a cochlear implant (CI), which stimulates the auditory nerve fibers. However, patients who do not have an intact auditory nerve cannot benefit from a CI. The majority of these patients are neurofibromatosis type 2 (NF2) patients who developed neural deafness due to growth or surgical removal of a bilateral acoustic neuroma. The only current solution is the auditory brainstem implant (ABI), which stimulates the surface of the cochlear nucleus in the brainstem. Although the ABI provides improvement in environmental awareness and lip-reading capabilities, only a few NF2 patients have achieved some limited open set speech perception. In the search for alternative procedures our research group in collaboration with Cochlear Ltd. (Australia) developed a human prototype auditory midbrain implant (AMI), which is designed to electrically stimulate the inferior colliculus (IC). The IC has the potential as a new target for an auditory prosthesis as it provides access to neural projections necessary for speech perception as well as a systematic map of spectral information. In this paper the present status of research and development in the field of central auditory prostheses is presented with respect to technology, surgical technique and hearing results as well as the background concepts of ABI and AMI. PMID:19517084

  6. Central pontine myelinolysis.

    Science.gov (United States)

    Kiley, M A; King, M; Burns, R J

    1999-03-01

    Central pontine myelinolysis (CPM) was initially associated with alcoholism. Subsequently other factors, including rapid reversal of hyponatraemia and extreme serum hypoosmolality associated with severe burns, have been identified as other important factors in its pathogenesis. Extra-pontine lesions have also been described. CPM may be found at autopsy, either having been overlooked during life or as an incidental finding. Its precise incidence is not known but the ability to diagnose it during life has been helped by modern neuroimaging, particularly magnetic resonance imaging (MRI) of the brain stem. In the past the prognosis for CPM was thought to be invariably fatal. It is clear now that with the greater general awareness of the disorder and the ability to diagnose it during life that some degree of recovery is possible. However, the number who do recover and the degree of recovery is not known. We report a 40-year-old man who developed CPM presenting with quadriparesis and inability to speak and swallow. There were risk factors for CPM and the diagnosis was confirmed by MRI scanning. He made a complete recovery although he remains ataxic. We are reporting this case as we believe it is important to make clinicians aware of the potential for recovery of CPM. While no specific treatment has been shown to influence the degree and rate of recovery of the demyelination, the fact that the quadriplegia and bulbar paralysis can recover fully is of considerable importance. In particular, it means that when the diagnosis is made, complete and vigorous nursing and medical care is warranted. PMID:18639140

  7. Central nervous system tumors

    International Nuclear Information System (INIS)

    Central nervous system (CNS) tumors are relatively common in veterinary medicine, with most diagnoses occurring in the canine and feline species. Numerous tumor types from various cells or origins have been identified with the most common tumors being meningiomas and glial cell tumors. Radiation therapy is often used as an aid to control the clinical signs associated with these neoplasms. In general, these tumors have a very low metastatic potential, such that local control offers substantial benefit. Experience in veterinary radiation oncology would indicate that many patients benefit from radiation treatment. Current practice indicates the need for computed tomography or magnetic resonance imaging studies. These highly beneficial studies are used for diagnosis, treatment planning, and to monitor treatment response. Improvements in treatment planning and radiation delivered to the tumor, while sparing the normal tissues, should improve local control and decrease potential radiation related problems to the CNS. When possible, multiple fractions of 3 Gy or less should be used. The tolerance dose to the normal tissue with this fractionation schedule is 50 to 55 Gy. The most common and serious complications of radiation for CNS tumors is delayed radiation myelopathy and necrosis. Medical management of the patient during radiation therapy requires careful attention to anesthetic protocols, and medications to reduce intracranial pressure that is often elevated in these patients. Canine brain tumors have served as an experimental model to test numerous new treatments. Increased availability of advanced imaging modalities has spawned increased detection of these neoplasms. Early detection of these tumors with appropriate aggressive therapy should prove beneficial to many patients

  8. Dublin South Central (DSC)

    LENUS (Irish Health Repository)

    O'Gorman, Clodagh S M

    2010-12-01

    Children who appear healthy, even if they have one or more recognized cardiovascular risk factors, do not generally have outcomes of cardiovascular or other vascular disease during childhood. Historically, pediatric medicine has not aggressively screened for or treated cardiovascular risk factors in otherwise healthy children. However, studies such as the P-Day Study (Pathobiological Determinants of Atherosclerosis in Youth), and the Bogalusa Heart Study, indicate that healthy children at remarkably young ages can have evidence of significant atherosclerosis. With the increasing prevalence of pediatric obesity, can we expect more health problems related to the consequences of pediatric dyslipidemia, hypertriglyceridemia, and atherosclerosis in the future? For many years, medications have been available and used in adult populations to treat dyslipidemia. In recent years, reports of short-term safety of some of these medications in children have been published. However, none of these studies have detailed long-term follow-up, and therefore none have described potential late side-effects of early cholesterol-lowering therapy, or potential benefits in terms of reduction of or delay in cardiovascular or other vascular end-points. In 2007, the American Heart Association published a scientific statement on the use of cholesterol-lowering therapy in pediatric patients. In this review paper, we discuss some of the current literature on cholesterol-lowering therapy in children, including the statins that are currently available for use in children, and some of the cautions with using these and other cholesterol-lowering medications. A central tenet of this review is that medications are not a substitute for dietary and lifestyle interventions, and that even in children on cholesterol-lowering medications, physicians should take every opportunity to encourage children and their parents to make healthy diet and lifestyle choices.

  9. y Banca Central

    Directory of Open Access Journals (Sweden)

    Ángel García Banchs

    2008-01-01

    Full Text Available Las teorías monetarias modernas, ortodoxas y heterodoxas, han pasado por alto el hecho de que posterior a la Segunda Guerra Mundial el mundo quedó dividido entre economías emisoras y receptoras de reservas, pasando el sistema monetario internacional desde entonces a ser completamente asimétrico. De allí que, desde el punto de vista teórico, señalemos la necesidad de tomar en cuenta si las economías emiten o no una moneda de reserva internacional, pues ello explicaría la existencia de diversas prácticas monetarias a nivel mundial. Este trabajo propone, y calcula, indicadores basados en datos provenientes de los balances de activos y pasivos de quince bancos centrales pertenecientes a Norteamérica, Suramérica, Europa y Asia. Los hallazgos con respecto a las diversas estructuras de activos y pasivos confirman la hipótesis acerca de la presencia de tales asimetrías. Se infiere en consecuencia que la política monetaria es menos flexible pero más influyente en las economías receptoras de reservas, y a la vez más flexible pero menos influyente en las economías emisoras. En pocas palabras, la exogeneidad de la tasa de interés de corto plazo es más débil en el caso de las economías receptoras de reservas las cuales se ven obligadas a acumular divisas y a procurar la estabilidad del tipo de cambio, debido a que sus monedas locales no son aceptadas en el exterior. Así, aunque la oferta crediticia es endógena en esas economías, las mismas no han sido capaces de librarse aún de la necesidad de mantener reservas monetarias en divisas extranjeras

  10. Central bank independence and ageing

    OpenAIRE

    Farvaque, Etienne; Héricourt, Jérôme; Lagadec, Gaël

    2008-01-01

    We contrast the influence of demography and central bank independence on inflation. The recent demographic trends in developed countries are shown to weight more on inflation than central bank independence, while the contrary stands for the period from 1960 to 1979.

  11. SQUARE AND RHOMBUS CENTRAL CONFIGURATIONS

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    In this paper, we consider the flat central configurations of bodies using the characteristic set method. We completely solve two special cases of four planets, namely,the square and the rhombus. For the square case, we obtain that a square is a central configuration only in the case where the masses are equal and there exactly are two different square central configurations determined by the mass and the angular velocity; for the rhombus case, we obtain that if a rhombus is a central configuration, then the masses of the diagonal vertices must be equal. Furthermore, there are two or three or four different rhombus central configurations determined by the masses and the angular velocity.

  12. Central control of body temperature.

    Science.gov (United States)

    Morrison, Shaun F

    2016-01-01

    Central neural circuits orchestrate the behavioral and autonomic repertoire that maintains body temperature during environmental temperature challenges and alters body temperature during the inflammatory response and behavioral states and in response to declining energy homeostasis. This review summarizes the central nervous system circuit mechanisms controlling the principal thermoeffectors for body temperature regulation: cutaneous vasoconstriction regulating heat loss and shivering and brown adipose tissue for thermogenesis. The activation of these thermoeffectors is regulated by parallel but distinct efferent pathways within the central nervous system that share a common peripheral thermal sensory input. The model for the neural circuit mechanism underlying central thermoregulatory control provides a useful platform for further understanding of the functional organization of central thermoregulation, for elucidating the hypothalamic circuitry and neurotransmitters involved in body temperature regulation, and for the discovery of novel therapeutic approaches to modulating body temperature and energy homeostasis. PMID:27239289

  13. Centralized versus Decentralized Information Systems

    Science.gov (United States)

    Hugoson, Mats-Åke

    This paper brings into question whether information systems should be centralized or decentralized in order to provide greater support for different business processes. During the last century companies and organizations have used different approaches for centralization and decentralization; a simple answer to the question does not exist. This paper provides a survey of the evolution of centralized and decentralized approaches, mainly in a Nordic perspective. Based on critical reflections on the situation in the end of the century we can discuss what we can learn from history to achieve alignment between centralized and decentralized systems and the business structure. The conclusion is that theories, management and practice for decisions on centralization or decentralization of information systems must be improved. A conscious management and control of centralization /decentralization of IT support is a vital question in the company or the organization, and this is not a task that can be handled only by IT-specialists. There is a need for business oriented IT management of centralization/decentralization.

  14. Betweenness centrality profiles in trees

    CERN Document Server

    Fish, Benjamin; Turan, Gyorgy

    2016-01-01

    Betweenness centrality of a vertex in a graph measures the fraction of shortest paths going through the vertex. This is a basic notion for determining the importance of a vertex in a network. The k-betweenness centrality of a vertex is defined similarly, but only considers shortest paths of length at most k. The sequence of k-betweenness centralities for all possible values of k forms the betweenness centrality profile of a vertex. We study properties of betweenness centrality profiles in trees. We show that for scale-free random trees, for fixed k, the expectation of k-betweenness centrality strictly decreases as the index of the vertex increases. We also analyze worst-case properties of profiles in terms of the distance of profiles from being monotone, and the number of times pairs of profiles can cross. This is related to whether k-betweenness centrality, for small values of k, may be used instead of having to consider all shortest paths. Bounds are given that are optimal in order of magnitude. We also pre...

  15. Central chemoreceptors: locations and functions.

    Science.gov (United States)

    Nattie, Eugene; Li, Aihua

    2012-01-01

    Central chemoreception traditionally refers to a change in ventilation attributable to changes in CO2/H(+) detected within the brain. Interest in central chemoreception has grown substantially since the previous Handbook of Physiology published in 1986. Initially, central chemoreception was localized to areas on the ventral medullary surface, a hypothesis complemented by the recent identification of neurons with specific phenotypes near one of these areas as putative chemoreceptor cells. However, there is substantial evidence that many sites participate in central chemoreception some located at a distance from the ventral medulla. Functionally, central chemoreception, via the sensing of brain interstitial fluid H(+), serves to detect and integrate information on (i) alveolar ventilation (arterial PCO2), (ii) brain blood flow and metabolism, and (iii) acid-base balance, and, in response, can affect breathing, airway resistance, blood pressure (sympathetic tone), and arousal. In addition, central chemoreception provides a tonic "drive" (source of excitation) at the normal, baseline PCO2 level that maintains a degree of functional connectivity among brainstem respiratory neurons necessary to produce eupneic breathing. Central chemoreception responds to small variations in PCO2 to regulate normal gas exchange and to large changes in PCO2 to minimize acid-base changes. Central chemoreceptor sites vary in function with sex and with development. From an evolutionary perspective, central chemoreception grew out of the demands posed by air versus water breathing, homeothermy, sleep, optimization of the work of breathing with the "ideal" arterial PCO2, and the maintenance of the appropriate pH at 37°C for optimal protein structure and function.

  16. Central European gas market perspectives

    International Nuclear Information System (INIS)

    This presentation deals with (1) Definition of the Central European market, (2) Factors driving up consumption of natural gas in Central and Eastern Europe, (3) Role of natural gas in regional energy consumption, (4) Position of natural gas in individual country markets, (5) Future sources of imported natural gas into the region. The Central European market are the eleven countries Albania, Bulgaria, Croatia, Czech Republic, Hungary, Macedonia, Poland, Romania, Serbia and Montenegro, Slovakia, and Slovenia, with a total population of 121 million. This market is comparable to combined France and Italy in terms of population, but only 30% of its size in terms of GDP

  17. Centralized digital control of accelerators

    International Nuclear Information System (INIS)

    In contrasting the title of this paper with a second paper to be presented at this conference entitled Distributed Digital Control of Accelerators, a potential reader might be led to believe that this paper will focus on systems whose computing intelligence is centered in one or more computers in a centralized location. Instead, this paper will describe the architectural evolution of SLAC's computer based accelerator control systems with respect to the distribution of their intelligence. However, the use of the word centralized in the title is appropriate because these systems are based on the use of centralized large and computationally powerful processors that are typically supported by networks of smaller distributed processors

  18. Demographic tensions in Central America.

    Science.gov (United States)

    1986-08-01

    This discussion of Central America focuses on the rapid growth of its population, its stagnating economy, and those countries that are socioeconomically advanced. Between 1950-85 the population of Central America tripled, from 9.1 million to 26. 4 million, due to marked mortality declines and the absence of off-setting fertility declines. The distribution of Central Americas's growing populations sets its population growth apart from that of other developing regions. Currently, almost half of all Central Americans live in cities. Although the average growth rate for Central American countries has fallen and is expected to drop further, the decline does not counterbalance the effect of the absolute rise in population numbers. The average annual growth rate of more than 3% annually in the 1960s fell to about 2.6% in recent years, but this decline is due primarily to socioeconomically advanced Costa Rica and Panama. Central America's age structure further complicates the population crisis. About 43% of Central Americans are under the age of 15. When the increasingly larger young population group enters it reproductive years, the potential for future growth (albeit the falling rate of population increase) is unparalleled. UN population projections show the region's population at 40 million by the year 2000. The 1973 oil crisis began a downward spiral for the buoyant post World War II Central American economy. Between 1950-79, real per capita income growth in Central America doubled, with Central American economies growing an average of 5.3% annually. By the early 1980s, overseas markets of the trade-dependent countries of Central America had dried up due to protectionism abroad and slumping basic commodity prices. These and other factors plunged Central America into its current economic malaise of falling real per capita income, rising unemployment, curtailed export led economic growth, and a rising cost of living. In general, economic growth in Central America

  19. The Central Trigger Processor (CTP)

    CERN Multimedia

    Franchini, Matteo

    2016-01-01

    The Central Trigger Processor (CTP) receives trigger information from the calorimeter and muon trigger processors, as well as from other sources of trigger. It makes the Level-1 decision (L1A) based on a trigger menu.

  20. Curability of cancer by radiotherapy and chemotherapy, including in neuraxial neoplasms

    Directory of Open Access Journals (Sweden)

    Jalali Rakesh

    2009-01-01

    Full Text Available In the October of 1996, Lance Armstrong, celebrated cyclist and one of the greatest athletes the world has ever seen, at the age of 24, was diagnosed with metastatic testicular cancer with disease having already spread to his abdomen, lungs and brain. Lance underwent four cycles of chemotherapy, actually the pretty standard one, pioneered at the Indiana University and not only did he get completely cured of his cancer, he remains extremely well till date, 12 years later. He sure did have a few adverse effects during those cycles of chemotherapy in the form of nausea, vomiting, weakness and fall in blood count but he knew and experienced them only for a short transient time and emerged triumphant and strong. In fact, he went on to win six awe-inspiring and incredible successive Tours de France victories from 1999-2005, one of the most grueling sporting events testing the endurance of the very fittest. After his retirement, he has been so inspired that he has completely devoted himself to educate people about the common myths about cancer, and promised to raise awareness and generate money for furthering research into surgery, radiation therapy and chemotherapy for cancer through his foundation. He says "I am indebted to the doctors, nurses and medicine and would want to pay them back for all their energy and caring." In his successful journey of overcoming cancer, he captures the essence of its treatment so well by declaring "Pain is temporary, it may last a minute, or an hour, or a day, or a year, but eventually, it will subside and something else will take its place. If I quit, however, it will last forever".

  1. Management of Neuraxial Anaesthesia for Emergent Caesarean Section for Placenta Previa.

    Science.gov (United States)

    Günaydın, Berrin; Kurdoğlu, Mertihan; Güler, İsmail; Bashiri, Mehrnoosh; Büyüktaşkın, Fırat; Keleşoğlu, Mine Dağgez; İnan, Gözde

    2016-02-01

    Abnormal placental attachments, such as placenta accreta, increta or percrata, can result in increased morbidity and mortality because of the risk of severe postpartum haemorrhage. We aimed to present the management of spinal anaesthesia and surgical approach for emergent caesarean section because of vaginal bleeding in a multiparous pregnant woman with placenta previa at 36 weeks' gestation. Hyperbaric bupivacaine 12 mg, fentanyl 10 μg and morphine 150 μg were intrathecally administered for spinal anaesthesia. Oxytocin, methyl ergonovin and tranexamic acid were administered after umbilical cord clamping. Breech delivery of the baby was provided by a vertical incision to the uterus for avoiding placental harm. Subtotal hysterectomy was performed leaving the placenta in situ. Two units of red blood cells were transfused during the operation, lasting approximately 40 min. The patient was uneventfully discharged on the postoperative fourth day. In conclusion, a single-shot spinal anaesthesia was successfully maintained without conversion to general anaesthesia until the end of the hysterectomy in the patient in whom placenta increta was observed during caesarean delivery.

  2. Brachial Plexus Root Injection in a Human Cadaver Model Injectate Distribution and Effects on the Neuraxis

    NARCIS (Netherlands)

    Orebaugh, Steven L.; Mukalel, Jessen J.; Krediet, Annalot C.; Weimer, Jonathan; Filip, Patrick; McFadden, Kathryn; Bigeleisen, Paul E.

    2012-01-01

    Background: The potential for injection into the brachial plexus root at cervical levels must be considered during interscalene block or chronic pain interventions in the neck, but this phenomenon has not been well studied. In this investigation, we performed injections into the brachial plexus root

  3. A Clinical Approach to Neuraxial Morphine for the Treatment of Postoperative Pain

    Directory of Open Access Journals (Sweden)

    Borja Mugabure Bujedo

    2012-01-01

    Full Text Available Opioids are considered a “gold standard” in clinical practice for the treatment of postoperative pain. The spinal administration of an opioid drug does not guarantee selective action and segmental analgesia in the spine. Evidence from experimental studies in animals indicates that bioavailability in the spinal cord biophase is negatively correlated with liposolubility, and is higher for hydrophilic opioids, such as morphine, than lipophilic opioids, such as fentanyl, sufentanil and alfentanil. Epidural morphine sulphate has proven analgesic efficacy and superiority over systemically administered morphine for improving postoperative pain. However, pain relief after a single epidural injection of morphine could last less than 24 hours. Techniques used to administered and prolong opioid epidural analgesia, can be costly and inconvenient. Moreover, complications can arise from indwelling epidural catheterization, particularly in patients receiving anticoagulants. Clinical trials have shown that epidural morphine in the form of extended-release liposome injections (EREM gives good analgesia for a period of 48 hours, with no need for epidural catheterisation. Intrathecal morphine produces intense analgesia for up to 24 hours with a single shot, and clinical recommendation is to choose the minimum effective dose and do not exceed 300 μg to prevent the delay respiratory depression.

  4. Curability of cancer by radiotherapy and chemotherapy, including in neuraxial neoplasms.

    Science.gov (United States)

    Jalali, Rakesh; Munshi, Anusheel; Arora, Brijesh

    2009-01-01

    In the October of 1996, Lance Armstrong, celebrated cyclist and one of the greatest athletes the world has ever seen, at the age of 24, was diagnosed with metastatic testicular cancer with disease having already spread to his abdomen, lungs and brain. Lance underwent four cycles of chemotherapy, actually the pretty standard one, pioneered at the Indiana University and not only did he get completely cured of his cancer, he remains extremely well till date, 12 years later. He sure did have a few adverse effects during those cycles of chemotherapy in the form of nausea, vomiting, weakness and fall in blood count but he knew and experienced them only for a short transient time and emerged triumphant and strong. In fact, he went on to win six awe-inspiring and incredible successive Tours de France victories from 1999-2005, one of the most grueling sporting events testing the endurance of the very fittest. After his retirement, he has been so inspired that he has completely devoted himself to educate people about the common myths about cancer, and promised to raise awareness and generate money for furthering research into surgery, radiation therapy and chemotherapy for cancer through his foundation. He says "I am indebted to the doctors, nurses and medicine and would want to pay them back for all their energy and caring." In his successful journey of overcoming cancer, he captures the essence of its treatment so well by declaring "Pain is temporary, it may last a minute, or an hour, or a day, or a year, but eventually, it will subside and something else will take its place. If I quit, however, it will last forever". PMID:19305070

  5. Audit Committees in Central Banks

    OpenAIRE

    Kenneth Sullivan; Marie-Therese Camilleri; Tonny Lybek

    2007-01-01

    This paper reviews the tasks and design of audit committees, increasingly recommended as a way to strengthen financial accountability and good central bank governance. It outlines the motivations for the establishment of audit committees in commercial corporations and public sector entities, and explains how audit committees interact with other governance bodies within a central bank. The paper focuses on the functions of an audit committee, since the terminology of the governance structure i...

  6. CENTRAL PLATEAU REMEDIATION OPTIMIZATION STUDY

    Energy Technology Data Exchange (ETDEWEB)

    BERGMAN, T. B.; STEFANSKI, L. D.; SEELEY, P. N.; ZINSLI, L. C.; CUSACK, L. J.

    2012-09-19

    THE CENTRAL PLATEAU REMEDIATION OPTIMIZATION STUDY WAS CONDUCTED TO DEVELOP AN OPTIMAL SEQUENCE OF REMEDIATION ACTIVITIES IMPLEMENTING THE CERCLA DECISION ON THE CENTRAL PLATEAU. THE STUDY DEFINES A SEQUENCE OF ACTIVITIES THAT RESULT IN AN EFFECTIVE USE OF RESOURCES FROM A STRATEGIC PERSPECTIVE WHEN CONSIDERING EQUIPMENT PROCUREMENT AND STAGING, WORKFORCE MOBILIZATION/DEMOBILIZATION, WORKFORCE LEVELING, WORKFORCE SKILL-MIX, AND OTHER REMEDIATION/DISPOSITION PROJECT EXECUTION PARAMETERS.

  7. Rogoff's 'Conservative' Central Banker Restored

    OpenAIRE

    Herrendorf, Berthold; Lockwood, Ben

    1996-01-01

    This paper shows that delegation of monetary policy to a weight-conservative central banker is optimal, although the government can also use an inflation contract, an employment target, an inflation target, or any combination of these, to control the central banker. The key feature of our model is a stochastic inflation bias, arising when wage-setters receive some information about a supply shock prior to signing nominal wage contracts. Weight-conservatism is shown to be desirable if the stoc...

  8. Congenital nystagmus and central hypothyroidism

    OpenAIRE

    Reynaert, Nele; Braat, Elke; de Zegher, Francis

    2015-01-01

    We observed a male newborn with bilateral nystagmus and central hypothyroidism without hypoprolactinemia due to a deletion of chromosome band Xq26.1q26.2, containing FRMD7 and IGSF1. These two loss-of function mutations are known to cause, respectively, congenital nystagmus and the ensemble of central hypothyroidism, hypoprolactinemia and testicular enlargement. These latter two features may not yet be present in early life.

  9. Coverage centralities for temporal networks*

    Science.gov (United States)

    Takaguchi, Taro; Yano, Yosuke; Yoshida, Yuichi

    2016-02-01

    Structure of real networked systems, such as social relationship, can be modeled as temporal networks in which each edge appears only at the prescribed time. Understanding the structure of temporal networks requires quantifying the importance of a temporal vertex, which is a pair of vertex index and time. In this paper, we define two centrality measures of a temporal vertex based on the fastest temporal paths which use the temporal vertex. The definition is free from parameters and robust against the change in time scale on which we focus. In addition, we can efficiently compute these centrality values for all temporal vertices. Using the two centrality measures, we reveal that distributions of these centrality values of real-world temporal networks are heterogeneous. For various datasets, we also demonstrate that a majority of the highly central temporal vertices are located within a narrow time window around a particular time. In other words, there is a bottleneck time at which most information sent in the temporal network passes through a small number of temporal vertices, which suggests an important role of these temporal vertices in spreading phenomena. Contribution to the Topical Issue "Temporal Network Theory and Applications", edited by Petter Holme.Supplementary material in the form of one pdf file available from the Journal web page at http://dx.doi.org/10.1140/epjb/e2016-60498-7

  10. Network centrality of metro systems.

    Directory of Open Access Journals (Sweden)

    Sybil Derrible

    Full Text Available Whilst being hailed as the remedy to the world's ills, cities will need to adapt in the 21(st century. In particular, the role of public transport is likely to increase significantly, and new methods and technics to better plan transit systems are in dire need. This paper examines one fundamental aspect of transit: network centrality. By applying the notion of betweenness centrality to 28 worldwide metro systems, the main goal of this paper is to study the emergence of global trends in the evolution of centrality with network size and examine several individual systems in more detail. Betweenness was notably found to consistently become more evenly distributed with size (i.e. no "winner takes all" unlike other complex network properties. Two distinct regimes were also observed that are representative of their structure. Moreover, the share of betweenness was found to decrease in a power law with size (with exponent 1 for the average node, but the share of most central nodes decreases much slower than least central nodes (0.87 vs. 2.48. Finally the betweenness of individual stations in several systems were examined, which can be useful to locate stations where passengers can be redistributed to relieve pressure from overcrowded stations. Overall, this study offers significant insights that can help planners in their task to design the systems of tomorrow, and similar undertakings can easily be imagined to other urban infrastructure systems (e.g., electricity grid, water/wastewater system, etc. to develop more sustainable cities.

  11. Network centrality of metro systems.

    Science.gov (United States)

    Derrible, Sybil

    2012-01-01

    Whilst being hailed as the remedy to the world's ills, cities will need to adapt in the 21(st) century. In particular, the role of public transport is likely to increase significantly, and new methods and technics to better plan transit systems are in dire need. This paper examines one fundamental aspect of transit: network centrality. By applying the notion of betweenness centrality to 28 worldwide metro systems, the main goal of this paper is to study the emergence of global trends in the evolution of centrality with network size and examine several individual systems in more detail. Betweenness was notably found to consistently become more evenly distributed with size (i.e. no "winner takes all") unlike other complex network properties. Two distinct regimes were also observed that are representative of their structure. Moreover, the share of betweenness was found to decrease in a power law with size (with exponent 1 for the average node), but the share of most central nodes decreases much slower than least central nodes (0.87 vs. 2.48). Finally the betweenness of individual stations in several systems were examined, which can be useful to locate stations where passengers can be redistributed to relieve pressure from overcrowded stations. Overall, this study offers significant insights that can help planners in their task to design the systems of tomorrow, and similar undertakings can easily be imagined to other urban infrastructure systems (e.g., electricity grid, water/wastewater system, etc.) to develop more sustainable cities. PMID:22792373

  12. Coverage centralities for temporal networks

    CERN Document Server

    Takaguchi, Taro; Yoshida, Yuichi

    2015-01-01

    Structure of real networked systems, such as social relationship, can be modeled as temporal networks in which each edge appears only at the prescribed time. Understanding the structure of temporal networks requires quantifying the importance of a temporal vertex, which is a pair of vertex index and time. In this paper, we define two centrality measures of a temporal vertex by the proportion of (normal) vertex pairs, the quickest routes between which can (or should) use the temporal vertex. The definition is free from parameters and robust against the change in time scale on which we focus. In addition, we can efficiently compute these centrality values for all temporal vertices. Using the two centrality measures, we reveal that distributions of these centrality values of real-world temporal networks are heterogeneous. For various datasets, we also demonstrate that a majority of the highly central temporal vertices are located within a narrow time window around a particular time. In other words, there is a bo...

  13. Pathophysiology of central sleep apneas.

    Science.gov (United States)

    Hernandez, Adam B; Patil, Susheel P

    2016-05-01

    The transition from wake to sleep is accompanied by a host of physiologic changes, which result in major alterations in respiratory control and may result in sleep-related breathing disorders. The central sleep apneas are a group of sleep-related breathing disorders that are characterized by recurrent episodes of airflow reduction or cessation due to a temporary reduction or absence of central respiratory drive. The fundamental hallmark of central sleep apnea (CSA) disorders is the presence of ventilatory control instability; however, additional mechanisms play a role in one or more specific manifestations of CSA. CSA may manifest during conditions of eucapnia/hypocapnia or chronic hypercapnia, which is a useful clinical classification that lends understanding to the underlying pathophysiology and potential therapies. In this review, an overview of normal breathing physiology is provided, followed by a discussion of pathophysiologic mechanisms that promote CSA and the mechanisms that are specific to different manifestations of CSA. PMID:26782104

  14. Central Clearing of OTC Derivatives

    DEFF Research Database (Denmark)

    Cont, Rama; Kokholm, Thomas

    2014-01-01

    We study the impact of central clearing of over-the-counter (OTC) transactions on counterparty exposures in a market with OTC transactions across several asset classes with heterogeneous characteristics. The impact of introducing a central counterparty (CCP) on expected interdealer exposure...... is determined by the tradeoff between multilateral netting across dealers on one hand and bilateral netting across asset classes on the other hand. We find this tradeoff to be sensitive to assumptions on heterogeneity of asset classes in terms of `riskyness' of the asset class as well as correlation...... of exposures across asset classes. In particular, while an analysis assuming independent, homogeneous exposures suggests that central clearing is efficient only if one has an unrealistically high number of participants, the opposite conclusion is reached if differences in riskyness and correlation across asset...

  15. Network Centrality of Metro Systems

    OpenAIRE

    Sybil Derrible

    2012-01-01

    Whilst being hailed as the remedy to the world's ills, cities will need to adapt in the 21(st) century. In particular, the role of public transport is likely to increase significantly, and new methods and technics to better plan transit systems are in dire need. This paper examines one fundamental aspect of transit: network centrality. By applying the notion of betweenness centrality to 28 worldwide metro systems, the main goal of this paper is to study the emergence of global trends in the e...

  16. /S/ in Central American Spanish.

    Science.gov (United States)

    Lipski, John M.

    1985-01-01

    Describes the behavior of the phoneme /s/ in Central American Spanish by comparing the speech patterns of residents of Guatemala City, San Salvador, Tegucigalpa, San Jose, and Managua. Considers the possible diachronic processes which could have given rise to the current configurations and the theoretical consequences implied by the…

  17. Copycats of the Central Himalayas

    NARCIS (Netherlands)

    P.A. Arora (Payal)

    2009-01-01

    textabstractThis case study highlights practices of a rarely documented group of neo-users of the Internet or newbies from Central Himalayas, serving as a catalyst for delving deeply into the act of ‘plagiarism’ in online learning By looking at such ‘learning’ practices away from schools, namely at

  18. Illustrating the Central Limit Theorem

    Science.gov (United States)

    Corcoran, Mimi

    2016-01-01

    Statistics is enjoying some well-deserved limelight across mathematics curricula of late. Some statistical concepts, however, are not especially intuitive, and students struggle to comprehend and apply them. As an AP Statistics teacher, the author appreciates the central limit theorem as a foundational concept that plays a crucial role in…

  19. Payments and Central Bank Policy

    DEFF Research Database (Denmark)

    Korsgaard, Søren

    This thesis consists of three chapters. The rst, "Paying for Payments", examines the role of interchange fees in payment card networks. The second, "Bank Liquidity and the Interbank Market" (co-authored with Mikael Reimer Jensen), investigates how banks' liquidity holdings at the central bank a e...

  20. New Economy, Old Central Banks?

    NARCIS (Netherlands)

    Berk, Jan Marc

    2002-01-01

    Proponents of the so-called New Economy claim that it entails a structural change of the economy. Such a change, in turn, would require the central bank to rethink its monetary policy to the extent that traditional relationships between inf1ation and economic growth are no longer valid. But such a r

  1. The CMS central hadron calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Freeman, J.; E892 Collaboration

    1996-12-31

    The CMS central hadron calorimeter is a copper absorber/ scintillator sampling structure. We describe design choices that led us to this concept, details of the mechanical and optical structure, and test beam results. We discuss calibration techniques, and finally the anticipated construction schedule.

  2. Centrality Metric for Dynamic Networks

    CERN Document Server

    Lerman, Kristina; Kang, Jeon Hyung

    2010-01-01

    Centrality is an important notion in network analysis and is used to measure the degree to which network structure contributes to the importance of a node in a network. While many different centrality measures exist, most of them apply to static networks. Most networks, on the other hand, are dynamic in nature, evolving over time through the addition or deletion of nodes and edges. A popular approach to analyzing such networks represents them by a static network that aggregates all edges observed over some time period. This approach, however, under or overestimates centrality of some nodes. We address this problem by introducing a novel centrality metric for dynamic network analysis. This metric exploits an intuition that in order for one node in a dynamic network to influence another over some period of time, there must exist a path that connects the source and destination nodes through intermediaries at different times. We demonstrate on an example network that the proposed metric leads to a very different ...

  3. A First for Central America

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    FTA gives impetus to China’s trade with Costa Rica and other countries in the region The free trade agreement (FTA) between China and Costa Rica, signed in April 2010,came into effect on August 1.It was the first free trade pact between China and a Central

  4. The MEANING multilingual central repository

    NARCIS (Netherlands)

    Atserias, J.; Villarejo, L.; Rigau, G.; Agirre, E.; Carroll, J.; Magnini, B.; Vossen, P.

    2004-01-01

    This paper describes the first version of the Multilingual Central Repository, a lexical knowledge base developed in the framework of the MEANING project. Currently the MCR integrates into the EuroWordNet framework five local wordnets (including four versions of the English WordNet from Princeton),

  5. Central Libraries in Uncertain Times.

    Science.gov (United States)

    Kenney, Brian J.

    2001-01-01

    Discusses security and safety issues for public libraries, especially high-profile central facilities, in light of the September 11 terrorist attacks. Highlights include inspecting bags as patrons enter as well as exit; the need for security guidelines for any type of disaster or emergency; building design; and the importance of communication.…

  6. From Centrality to Temporary Fame: Dynamic Centrality in Complex Networks

    OpenAIRE

    Braha, Dan; Bar-Yam, Yaneer

    2006-01-01

    We develop a new approach to the study of the dynamics of link utilization in complex networks using records of communication in a large social network. Counter to the perspective that nodes have particular roles, we find roles change dramatically from day to day. "Local hubs" have a power law degree distribution over time, with no characteristic degree value. Our results imply a significant reinterpretation of the concept of node centrality in complex networks, and among other conclusions su...

  7. Central hypersensitivity in chronic musculoskeletal pain

    DEFF Research Database (Denmark)

    Curatolo, Michele; Arendt-Nielsen, Lars

    2015-01-01

    Clinical research has consistently detected alteration in central pain processing leading to hypersensitivity. Most methods used in humans are reliable and have face validity to detect widespread central hypersensitivity. However, construct validity is difficult to investigate due to lack of gold...... standards. Reference values in the pain-free population have been generated, but need replication. Research on pain biomarkers that reflect specific central hypersensitivity processes is warranted. Few studies have analyzed the prognostic value of central hypersensitivity. Most medications acting at central...

  8. Centralized versus Decentralized Infrastructure Networks

    CERN Document Server

    Hines, Paul D H; Schläpfer, Markus

    2015-01-01

    While many large infrastructure networks, such as power, water, and natural gas systems, have similar physical properties governing flows, these systems tend to have distinctly different sizes and topological structures. This paper seeks to understand how these different size-scales and topological features can emerge from relatively simple design principles. Specifically, we seek to describe the conditions under which it is optimal to build decentralized network infrastructures, such as a microgrid, rather than centralized ones, such as a large high-voltage power system. While our method is simple it is useful in explaining why sometimes, but not always, it is economical to build large, interconnected networks and in other cases it is preferable to use smaller, distributed systems. The results indicate that there is not a single set of infrastructure cost conditions under which optimally-designed networks will have highly centralized architectures. Instead, as costs increase we find that average network size...

  9. Centrality in Interconnected Multilayer Networks

    CERN Document Server

    De Domenico, Manlio; Omodei, Elisa; Gómez, Sergio; Arenas, Alex

    2013-01-01

    Real-world complex systems exhibit multiple levels of relationships. In many cases, they require to be modeled by interconnected multilayer networks, characterizing interactions on several levels simultaneously. It is of crucial importance in many fields, from economics to biology, from urban planning to social sciences, to identify the most (or the less) influent nodes in a network. However, defining the centrality of actors in an interconnected structure is not trivial. In this paper, we capitalize on the tensorial formalism, recently proposed to characterize and investigate this kind of complex topologies, to show how several centrality measures -- well-known in the case of standard ("monoplex") networks -- can be extended naturally to the realm of interconnected multiplexes. We consider diagnostics widely used in different fields, e.g., computer science, biology, communication and social sciences, to cite only some of them. We show, both theoretically and numerically, that using the weighted monoplex obta...

  10. A centralized audio presentation manager

    Energy Technology Data Exchange (ETDEWEB)

    Papp, A.L. III; Blattner, M.M.

    1994-05-16

    The centralized audio presentation manager addresses the problems which occur when multiple programs running simultaneously attempt to use the audio output of a computer system. Time dependence of sound means that certain auditory messages must be scheduled simultaneously, which can lead to perceptual problems due to psychoacoustic phenomena. Furthermore, the combination of speech and nonspeech audio is examined; each presents its own problems of perceptibility in an acoustic environment composed of multiple auditory streams. The centralized audio presentation manager receives abstract parameterized message requests from the currently running programs, and attempts to create and present a sonic representation in the most perceptible manner through the use of a theoretically and empirically designed rule set.

  11. PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA

    Directory of Open Access Journals (Sweden)

    S.S. Anvari

    2009-08-01

    Full Text Available ObjectivePrimary central nervous system lymphoma (PCNSL is an extremely rare condition in childhood. We report the first case of PCNSL in a child in Iran.Clinical presentationA nine-year-old boy was referred to Mofid Hospital with the history of headache of four months and seizure of 2 months duration. Magnetic resonance imaging of the brain revealed a hyper-intense lesion in left fronto-parietal area with secondary satellite lesions. Biopsy of the brain mass was performed. Pathologic findings showed brain lymphoma and immunohistochemistry confirmed this diagnosis. The treatment started with intrathecal and systemic chemotherapy in combination with radiotherapy.Keywords:Lymphoma, Primary central nervous system lymphoma (PCNSL, Children

  12. Celtic Sites of Central Iberia

    Science.gov (United States)

    Pérez Gutiérrez, Manuel

    This chapter concerns the astronomy practiced by Celtic peoples in some parts of central Iberia, specifically the Vetton and Celtiberian peoples, inhabitants of the so-called Late Iron Age. The construction of some elements of religion or worship was perfectly determined by geometry, topography, and especially astronomy, because their spatial orientation occurs in locations of great interest for maintaining the local calendar. The maintenance of this calendar was probably the primary objective of some of the elements studied.

  13. Information from the central stores

    CERN Multimedia

    GS Department

    2010-01-01

    All items sold in the CERN shop (Bldg. 33) are now available in the central stores (Bldg. 73) and can be purchased on-line via EDH “Material Request” or at the “Emergency Desk” of the stores on the ground floor of Bldg. 73. These items are visible in the CERN catalogue under the “SCEM” codes beginning with 92. Department of General Infrastructure Services (GS) GS-SEM Group

  14. Wine markets in central Europe

    OpenAIRE

    Š BOJNEC

    2013-01-01

    This paper analyses the tendencies of grapes growing, wine trading and wine price competitiveness in Central European region. Croatia is net exporter of wines, Hungary is net exporter of grapes and wines, and Austria, Slovakia, and Slovenia are net importers of grapes and wines. Reductions in vineyards and increase in yields are found for Austria, Hungary, and Slovakia. More stable developments in vineyards, but decline in yields, are found for Croatia and Slovenia. Grape production increases...

  15. Central collisions of heavy ions

    International Nuclear Information System (INIS)

    This report describes the activities of the Heavy Ion Physics Group at the University of California, Riverside from October 1, 1991 to September 30, 1992. During this period, the program focused on particle production at AGS energies, and correlation studies at the Bevalac in nucleus-nucleus central collisions. As part of the PHENIX collaboration, contributions were made to the Preliminary Conceptual Design Report (pCDR), and work on a RHIC silicon microstrip detector R ampersand D project was performed

  16. Plague in Central Java, Indonesia

    OpenAIRE

    Williams, J.E.; Hudson, B. W.; Turner, R W; Saroso, J. Sulianti; Cavanaugh, D. C.

    1980-01-01

    Plague in man occurred from 1968 to 1970 in mountain villages of the Boyolali Regency in Central Java. Infected fleas, infected rats, and seropositive rats were collected in villages with human plague cases. Subsequent isolations of Yersinia pestis and seropositive rodents, detected during investigations of rodent plague undertaken by the Government of Indonesia and the WHO, attested to the persistence of plague in the region from 1972 to 1974.

  17. Central Asian drug trafficking dilemma

    OpenAIRE

    McGowen, Richard S.

    2003-01-01

    Tajikistan, a state that is completely landlocked, consists of very rough terrain that is comprised of mountains, cliffs and glaciers. There are very few transportation links through the area that gives Tajikistan limited access to neighboring countries. Security problems resulting from the increasing flow of narcotics illegally smuggled across the 1200 km Tajikistan- Afghanistan border have become critical in understanding the nature of political instability within Central Asia. This thesis ...

  18. Optimal Central Counterparty Risk Management

    OpenAIRE

    Philipp Haene; Andy Sturm

    2009-01-01

    In order to protect themselves against the potential losses in case of a participant's default and to contain systemic risk, central counterparties (CCPs) need to maintain sufficient financial resources. Typically, these financial resources consist of margin requirements and contributions to a collective default fund. Based on a stylized model of CCP risk management, this article analyzes the main factors affecting the trade-off between margins and default fund. The optimal balance between th...

  19. Political centralization and government accountability

    OpenAIRE

    Boffa, Federico; Piolatto, Amedeo; Giacomo A. M. Ponzetto

    2011-01-01

    This paper explains why decentralization can undermine accountability and answers three questions: what determines if power should be centralized or decentralized when regions are heterogeneous? How many levels of government should there be? How should state borders be drawn? We develop a model of political agency in which voters differ in their ability to monitor rent-seeking politicians. We find that rent extraction is a decreasing and convex function of the share of informed...

  20. Kalmanovitz y la Banca central / Kalmanovitz and central banking

    OpenAIRE

    Maya Muñoz, Guillermo

    2004-01-01

    Salomón Kalmanovitz, Codirector del Banco de la República (B de la R) hasta enero de 2005, uno de los economistas colombianos más brillantes, publicó un libro titulado Ensayos sobre Banca Central, Comportamiento, Independencia e Historia (Norma, 2003). Si los estudiantes de economía de los años 70 y 80 estudiaron a un Kalmanovitz marxista, los estudiantes de hoy estudian a un economista ortodoxo y liberal, igualmente brillante. Kalmanovitz es un partidario de la independencia de la BC para la...

  1. From Centrality to Temporary Fame: Dynamic Centrality in Complex Networks

    CERN Document Server

    Braha, D; Braha, Dan; Bar-Yam, Yaneer

    2006-01-01

    We develop a new approach to the study of the dynamics of link utilization in complex networks using records of communication in a large social network. Counter to the perspective that nodes have particular roles, we find roles change dramatically from day to day. "Local hubs" have a power law degree distribution over time, with no characteristic degree value. Our results imply a significant reinterpretation of the concept of node centrality in complex networks, and among other conclusions suggest that interventions targeting hubs will have significantly less effect than previously thought.

  2. CHINA AND ENERGY SECURITY IN CENTRAL ASIA

    OpenAIRE

    Guang, Pan

    2007-01-01

    This paper is divided into three parts: China’s energy policy and energy development strategy; Central Asia’s significance for China’s overseas energy development strategy; and Central Asia’s energy security and energy development.

  3. Central diffractive resonance production at the LHC

    Directory of Open Access Journals (Sweden)

    Fiore Roberto

    2016-01-01

    Full Text Available Central production of resonances resulting from the scattering of Pomerons in the central rapidity region of proton-proton scattering is studied. Estimates for relevant cross sections are presented.

  4. Biomass energy in Central America

    International Nuclear Information System (INIS)

    The objective of this paper is to introduce the concept of biomass to energy issues and opportunities in Central America. In this region, made up of seven countries (Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama), the biomass sector has the potential to play a crucial role in alleviating the environmental and development predicaments faced by all economies of the region. This paper assesses the available biomass resources at the regional and country levels and gives an overview of the current utilization of biomass fuels. It also describes the overall context in which the biomass-to-energy initiatives are immersed. At the regional level, biomass energy consumption accounts for more than 50% of total energy consumption. In regard to the utilization of biomass for energy purposes, it is clear that Central America faces a critical juncture at two levels, both mainly in rural areas: in the productive sector and at the household level. The absence of sustainable development policies and practices has jeopardized the availability of biomass fuels, particularly wood. Firewood is an important source of energy for rural industries such as coffee processing, which is one of the largest productive activities in the region. This paper comments on some of the most successful technological innovations already in place in the region, for instance, the rapid development of co-generation projects by the sugar cane industry, especially in El Salvador and Guatemala, the substitution of coffee husks for firewood in coffee processing plants in Costa Rica and El Salvador and the sustainable use of pine forests for co-generation in Honduras. Only one out of every two inhabitants in Central America now has access to electricity from the public grid. Biomass fuels, mainly firewood but also, to a lesser extent, other crop residues such as corn stalks, are the main source of energy for cooking and heating by most of the population. (It is foreseen that by the end

  5. The ZEUS central tracking detector

    International Nuclear Information System (INIS)

    The Central Tracking Detector (CTD) of ZEUS covers a wide angular range, whilst the Forward Detector - comprising the Forward Tracking Detector (FTD) and electron identification by transition radiation - concentrates on the important forward cone. The RTD (Rear Tracking Detector) provides accurate angle measurement of the recoil electron and the vertex detector (VXD) aims to find particles from heavy flavour decay. To measure momentum accurately the CTD sits in a high magnetic field (B=1,8 T) within the ZEUS calorimeter. (orig./HSI)

  6. Legal and actual central bank independence

    OpenAIRE

    Artha, I.K.D.S.; J. de Haan

    2010-01-01

    Indicators of central bank independence (CBI) based on the interpretation central bank laws in place may not capture the actual independence of the central bank. This paper develops an indicator of actual independence of the Bank Indonesia (BI), the central bank of Indonesia, for the period 1953-2008 and compares it with a new legal CBI indicator based on Cukierman (1992). The indicator of actual independence captures institutional and economic factors that affect CBI. We find that before 199...

  7. Accountability of central banks: aspects and quantification

    Directory of Open Access Journals (Sweden)

    J. DE HAAN

    1999-06-01

    Full Text Available The work examines the relationship between central bank independence and accountability. The authors do this by using an indicator for central bank accountability based on the laws of 16 central banks. Central bank accountability is identified as having three distinct features, namely, the explicit definition and ranking of the objectives of monetary policy, the transparency of the actual monetary policy, and the final responsibility to monetary policy.

  8. Distributed trace using central performance counter memory

    Science.gov (United States)

    Satterfield, David L.; Sexton, James C.

    2013-01-22

    A plurality of processing cores, are central storage unit having at least memory connected in a daisy chain manner, forming a daisy chain ring layout on an integrated chip. At least one of the plurality of processing cores places trace data on the daisy chain connection for transmitting the trace data to the central storage unit, and the central storage unit detects the trace data and stores the trace data in the memory co-located in with the central storage unit.

  9. Central bank independence and inflation revisited

    NARCIS (Netherlands)

    Klomp, Jeroen; de Haan, Jakob

    2010-01-01

    We re-examine the relationship between central bank independence (CBI), proxied by the central bank governor's turnover rate and an indicator based on central bank laws in place, and inflation using a random coefficient model with the Hildreth-Houck estimator for more than 100 countries in the perio

  10. Accountability of Central Banks : Aspects and Quantification

    NARCIS (Netherlands)

    de Haan, J.; Amtenbrink, F.; Eijffinger, S.C.W.

    1998-01-01

    This paper starts with a discussion of the various aspects of accountability of central banks. On the basis of this discussion we construct an indicator for accountability for 16 central banks, including the European Central Bank. It is shown that the degree of accountability differs considerably an

  11. "Christofest" New Yorgi Central Parkis / Rael Artel

    Index Scriptorium Estoniae

    Artel, Rael, 1980-

    2004-01-01

    12. II 2005. a. avatakse Christo ja Jeanne-Claude'i keskkonnainstallatsioon "The Gates" New Yorgi Central Parkis. Paralleelselt toimub Metropolitan Muuseumis näitus "Christo and Jeanne-Claude : The Gates, Central Park, New York", kus eksponeeritakse Central Parki installatsiooni ettevalmistavaid materjale: joonistusi, diagramme, fotosid jne

  12. Central and forward tracking collaboration

    International Nuclear Information System (INIS)

    The goal of this subsystem R ampersand D project is to carry out a detailed study and design of a complete wire chamber tracking system covering pseudorapidity |η| ≤ 2.5 in a solenoidal detector for the SSC. Most of our group are now part of the Solenoidal Detector Collaboration (SDC), so the work has evolved into developing a tracking system conceptual design for the SDC detector. The design discussed in this report uses straw tube drift chambers for the central tracking region. Because of the high rates in the SSC environment, a small cell design is needed for wire chambers in the central region. Straw tubes as small cells offer many advantages because the sense wire is enclosed in a continuous cathode, and the wire tension due to the sense wire only can be supported without a massive structure. The straw tubes are grouped together to form superlayers in order to provide local track segments. The superlayers are composed of modules consisting of about two hundred straw tubes enclosed in a carbon fiber composite shell. Straw tubes have been used in previous experiments for small vertex drift chambers. However, they have never before been used for a large tracking system

  13. Precipitation chemistry in central Amazonia

    Science.gov (United States)

    Andreae, M. O.; Talbot, R. W.; Berresheim, H.; Beecher, K. M.

    1990-01-01

    Rain samples from three sites in central Amazonia were collected over a period of 6 weeks during the 1987 wet season and analyzed for ionic species and dissolved organic carbon. A continuous record of precipitation chemistry and amount was obtained at two of these sites, which were free from local or regional pollution, for a time period of over 1 month. The volume-weighted mean concentrations of most species were found to be about a factor of 5 lower during the wet season compared with previous results from the dry season. Only sodium, potassium, and chloride showed similar concentrations in both seasons. When the seasonal difference in rainfall amount is taken into consideration, the deposition fluxes are only slightly lower for most species during the wet season than during the dry season, again with the exception of chloride, potassium, and sodium. Sodium and chloride are present in the same ratio as in sea salt; rapid advection of air masses of marine origin to the central Amazon Basin during the wet season may be responsible for the observed higher deposition flux of these species. Statistical analysis suggests that sulfate is, to a large extent, of marine (sea salt and biogenic) origin, but that long-range transport of combustion-derived aerosols also makes a significant contribution to sulfate and nitrate levels in Amazonian rain. Organic acid concentrations in rain were responsible for a large fraction of the observed precipitation acidity; their concentration was strongly influenced by gas/liquid interactions.

  14. Central Equatorial Pacific Experiment (CEPEX)

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    The Earth's climate has varied significantly in the past, yet climate records reveal that in the tropics, sea surface temperatures seem to have been remarkably stable, varying by less than a few degrees Celsius over geologic time. Today, the large warm pool of the western Pacific shows similar characteristics. Its surface temperature always exceeds 27[degree]C, but never 31[degree]C. Heightened interest in this observation has been stimulated by questions of global climate change and the exploration of stabilizing climate feedback processes. Efforts to understand the observed weak sensitivity of tropical sea surface temperatures to climate forcing has led to a number of competing ideas about the nature of this apparent thermostat. Although there remains disagreement on the processes that regulate tropical sea surface temperature, most agree that further progress in resolving these differences requires comprehensive field observations of three-dimensional water vapor concentrations, solar and infrared radiative fluxes, surface fluxes of heat and water vapor, and cloud microphysical properties. This document describes the Central Equatorial Pacific Experiment (CEPEX) plan to collect such observations over the central equatorial Pacific Ocean during March of 1993.

  15. Glial involvement in trigeminal central sensitization

    Institute of Scientific and Technical Information of China (English)

    Yu-feng XIE

    2008-01-01

    Recent studies have indicated that trigeminal neurons exhibit central sensitization, an increase in the excitability of neurons within the central nervous system to the extent that a normally innocuous stimulus begins to produce pain after inflamma-tion or injury, and that glial activities play a vital role in this central sensitization. The involvement of glial cells in trigeminal central sensitization contains multiple mechanisms, including interaction with glutamatergic and purinergic receptors. A better understanding of the trigeminal central sensitization mediated by glial cells will help to find potential therapeutic targets and lead to developing new analge-sics for orofacial-specific pain with higher efficiency and fewer side-effects.

  16. Central Solenoid Insert Technical Specification

    Energy Technology Data Exchange (ETDEWEB)

    Martovetsky, Nicolai N [ORNL; Smirnov, Alexandre [ORNL

    2011-09-01

    The US ITER Project Office (USIPO) is responsible for the ITER central solenoid (CS) contribution to the ITER project. The Central Solenoid Insert (CSI) project will allow ITER validation the appropriate lengths of the conductors to be used in the full-scale CS coils under relevant conditions. The ITER Program plans to build and test a CSI to verify the performance of the CS conductor. The CSI is a one-layer solenoid with an inner diameter of 1.48 m and a height of 4.45 m between electric terminal ends. The coil weight with the terminals is approximately 820 kg without insulation. The major goal of the CSI is to measure the temperature margin of the CS under the ITER direct current (DC) operating conditions, including determining sensitivity to load cycles. Performance of the joints, ramp rate sensitivity, and stability against thermal or electromagnetic disturbances, electrical insulation, losses, and instrumentation are addressed separately and therefore are not major goals in this project. However, losses and joint performance will be tested during the CSI testing campaign. The USIPO will build the CSI that will be tested at the Central Solenoid Model Coil (CSMC) Test Facility at the Japan Atomic Energy Agency (JAEA), Naka, Japan. The industrial vendors (the Suppliers) will report to the USIPO (the Company). All approvals to proceed will be issued by the Company, which in some cases, as specified in this document, will also require the approval of the ITER Organization. Responsibilities and obligations will be covered by respective contracts between the USIPO, called Company interchangeably, and the industrial Prime Contractors, called Suppliers. Different stages of work may be performed by more than one Prime Contractor, as described in this specification. Technical requirements of the contract between the Company and the Prime Contractor will be covered by the Fabrication Specifications developed by the Prime Contractor based on this document and approved by

  17. Performance contracting in central government in Denmark

    DEFF Research Database (Denmark)

    Kristiansen, Mads Bøge

    2015-01-01

    for maintaining the MBOR system including setting requirements and recommendations for the design and use of performance contracts, which means that a common central government framework for performance contracting exists. Despite of this common framework, differences in the contract content (scale and focus......This paper looks into performance contracting in Danish central government. Management by Objectives and Results (MBOR) was adopted in central government in Denmark during the 1980s and early 1990s. In 1991, performance contracts between parent ministries and their agencies were introduced...... in Danish central government. Since their introduction, performance contracts have become central elements in the steering and management of agencies in central government in Denmark, and today they are nearly universally adopted in central government. In Denmark, the Ministry of Finance is responsible...

  18. 76 FR 22746 - Wiregrass Central Railway, LLC-Acquisition and Operation Exemption-Wiregrass Central Railroad...

    Science.gov (United States)

    2011-04-22

    ... Surface Transportation Board Wiregrass Central Railway, LLC--Acquisition and Operation Exemption--Wiregrass Central Railroad Company, Inc. Wiregrass Central Railway, LLC (WCR), a noncarrier, has filed a verified notice of exemption under 49 CFR 1150.31 to acquire from Wiregrass Central Railroad Company,...

  19. WINE MARKETS IN CENTRAL EUROPE

    Directory of Open Access Journals (Sweden)

    Š BOJNEC

    2007-04-01

    Full Text Available This paper analyses the tendencies of grapes growing, wine trading and wine price competitiveness in Central European region. Croatia is net exporter of wines, Hungary is net exporter of grapes and wines, and Austria, Slovakia, and Slovenia are net importers of grapes and wines. Reductions in vineyards and increase in yields are found for Austria, Hungary, and Slovakia. More stable developments in vineyards, but decline in yields, are found for Croatia and Slovenia. Grape production increases in Austria, remains stable in Croatia, explores annual oscillations in Hungary, and declines in Slovakia and Slovenia. Export-to-import wine prices deteriorate for Austria and Hungary with most recent stabilization and price similarity, which hold also for Slovakia. Slovenian export-to-import wine prices are unstable, while Croatia experiences a bit higher export than import wine prices. Wine marketing, wine brand image of quality, and wine tourism are seen as tools to improve competitiveness in the wine sector.

  20. Centralized Allocation in Multiple Markets

    DEFF Research Database (Denmark)

    Monte, Daniel; Tumennasan, Norovsambuu

    The problem of allocating indivisible objects to different agents, where each indi vidual is assigned at most one object, has been widely studied. Pápai (2000) shows that the set of strategy-proof, nonbossy, Pareto optimal and reallocation-proof rules are hierarchical exchange rules | generalizat......The problem of allocating indivisible objects to different agents, where each indi vidual is assigned at most one object, has been widely studied. Pápai (2000) shows that the set of strategy-proof, nonbossy, Pareto optimal and reallocation-proof rules are hierarchical exchange rules...... | generalizations of Gale's Top Trading Cycles mechanism. We study the centralized allocation that takes place in multiple markets. For example, the assignment of multiple types of indivisible objects; or the assignment of objects in successive periods. We show that the set of strategy-proof, Pareto efficient...

  1. Central solar-energy receiver

    Science.gov (United States)

    Not Available

    1981-10-27

    An improved tower-mounted central solar energy receiver for heating air drawn through the receiver by an induced draft fan is described. A number of vertically oriented, energy absorbing, fin-shaped slats are radially arranged in a number of concentric cylindrical arrays on top of the tower coaxially surrounding a pipe having air holes through which the fan draws air which is heated by the slats which receive the solar radiation from a heliostat field. A number of vertically oriented and wedge-shaped columns are radially arranged in a number of concentric cylindrical clusters surrounding the slat arrays. The columns have two mirror-reflecting sides to reflect radiation into the slat arrays and one energy absorbing side to reduce reradiation and reflection from the slat arrays.

  2. Central Exclusive Production at LHCb

    CERN Document Server

    McNulty, Ronan

    2016-01-01

    Central Exclusive Production (CEP) is a unique process at hadron machines in which particles are produced via colourless propagators. LHCb have measured the cross-sections for the CEP of vector mesons, $J/\\psi,\\psi(2S),\\Upsilon(1S),\\Upsilon(2S)$ and $\\Upsilon(3S)$, which are photo-produced. In the double pomeron exchange process, preliminary measurements have been made of $\\chi_{c0},\\chi_{c1}, \\chi_{c2}$ meson production while the first observations of the CEP of pairs of charmonia, $J/\\psi J/\\psi$ and $J/\\psi \\psi(2S)$, have been made and limits obtained on the pair production of other charmonia.

  3. CST-01-Central Standard Timing

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    薄如蝉翼名为CentralStandardTiming的工作室推出了E—ink材质代号为CST-01的手表,其厚度仅为0.8mm,号称全球最薄。一次充电10分钟便可连续使用15年。该手表屏幕由多层柔性材料构成。整体十分轻巧并且可弯曲,腕带则采用了柔性不锈钢材质。CST-01的预售价格为129美元。约合人民币800元,目前已经在著名的集资网站Kickstarter上创建项目。

  4. Wooden Calendars from Central Rhodopes

    Science.gov (United States)

    Koleva, V.

    2008-10-01

    Four wooden calendars from the village of Polkovnik Serafimovo, Smolyan region, in the Central Rhodopes are presented here, and three of them - for the first time. The shape and size, the kind of the signs and structure of the calendar record bear the characteristic features of the rest of the Bulgarian wooden calendars. The short notches on the edges represent the days of the year in the Julian (solar) calendar. The special signs on the sides mark the fixed festivals of the Orthodox Church calendar and are also influenced by the local tradition. The type of the signs confirms that the wooden sticks belong to the group of calendars from the Central Rhodopes. According to the beginning date of the calendar record on the sticks, two of the calendars are of the April (May) or October (November) type which corresponds to the very popular economic division of the year in the folk calendar into two periods -- warm and cold. The other two sticks, which are very similar to each other, make an exception in this respect among the rest of the Bulgarian wooden calendars. The months are divided into four groups (seasons) on each of the four edges of the stick (only one calendar from Burgas region has the same structure). The most interesting thing about the two sticks is that this is the only case among all known Bulgarian calendars that the beginning of the calendar record coincides with the beginning of the civil year on 1st January (January type) like some wooden calendars from Western Europe. Nowadays it is getting harder and harder to find wooden calendars in Bulgaria and in the neighbouring Balkan countries. The thorough knowledge about them could be helpful in various scientific fields, e.g. history of religion, ethnology, history of astronomy and mathematics, as well as semiotics.

  5. Hirsch index as a network centrality measure

    CERN Document Server

    Campiteli, Monica G; Soles, Paulo R C; Soares, Leonardo H D; Kinouchi, Osame

    2010-01-01

    We study the h Hirsch index as a local node centrality measure for complex networks in general. The h index is compared with the Degree centrality (a local measure), the Betweenness and Eigenvector centralities (two non-local measures) in the case of a biological network (Yeast interaction protein-protein network) and a linguistic network (Moby Thesaurus II) as test environments. In both networks, the Hirsch index has poor correlation with Betweenness centrality but correlates well with Eigenvector centrality, specially for the more important nodes that are relevant for ranking purposes, say in Search Machine Optimization. In the thesaurus network, the h index seems even to outperform the Eigenvector centrality measure as evaluated by simple linguistic criteria.

  6. Reduced central blood volume in cirrhosis

    DEFF Research Database (Denmark)

    Bendtsen, F; Henriksen, Jens Henrik Sahl; Sørensen, T I;

    1989-01-01

    The pathogenesis of ascites formation in cirrhosis is uncertain. It is still under debate whether the effective blood volume is reduced (underfilling theory) or whether the intravascular compartment is expanded (overflow theory). This problem has not yet been solved because of insufficient tools...... for measuring the central blood volume. We have developed a method that enables us to determine directly the central blood volume, i.e., the blood volume in the heart cavities, lungs, and central arterial tree. In 60 patients with cirrhosis and 16 control subjects the central blood volume was assessed according...... to the kinetic theory as the product of cardiac output and mean transit time of the central vascular bed. Central blood volume was significantly smaller in patients with cirrhosis than in controls (mean 21 vs. 27 ml/kg estimated ideal body weight, p less than 0.001; 25% vs. 33% of the total blood volume, p less...

  7. Transpleural central venous catheter discovered during thoracotomy

    Directory of Open Access Journals (Sweden)

    Ashima Malhotra

    2014-01-01

    Full Text Available We report an uncommon complication of subclavian central venous catheterization, discovered at thoracotomy. The central venous catheter (CVC was placed by left infraclavicular route after induction of general anesthesia. CVC was secured after aspiration of blood and satisfactory central venous tracing. On thoracotomy, CVC was noticed to traverse the pleural cavity while the tracing was normal. CVC was thus removed consequent to which bleeding from each puncture site was noticed, that were secured surgically.

  8. Central sleep apnea – a case report

    OpenAIRE

    Dybala Andrzej; Dyczko Monika; Makaruk Boguslaw; Kicinski Pawel; Bartoszek Elzbieta; Myslinski Wojciech; Rahnama Mansur; Mosiewicz Jerzy

    2014-01-01

    Central sleep apnea (CSA) is a disease characterized by repetitive episodes of the socalled central apneas during sleep. The disease has a very complex etiology. In clinical practice, the most important causes of CSA are disorders of the central nervous system, congestive heart failure or certain pathological changes of the respiratory muscles. We present a case of a 43-year-old male with severe CSA, who was successfully treated with BiPAP ST equipment.

  9. Central sleep apnea – a case report

    Directory of Open Access Journals (Sweden)

    Dybala Andrzej

    2014-06-01

    Full Text Available Central sleep apnea (CSA is a disease characterized by repetitive episodes of the socalled central apneas during sleep. The disease has a very complex etiology. In clinical practice, the most important causes of CSA are disorders of the central nervous system, congestive heart failure or certain pathological changes of the respiratory muscles. We present a case of a 43-year-old male with severe CSA, who was successfully treated with BiPAP ST equipment.

  10. Central Neurogenic Respiratory Failure: A Challenging Diagnosis

    OpenAIRE

    Carvalho, Flávio A.; Bernardino, Tenille; Maciel, Ricardo O.H.; Felizola, Sérgio F.A.; Costa, Eduardo L.V.; Silva, Gisele S

    2011-01-01

    Background Central nervous system lesions are rare causes of respiratory failure. Simple observation of the breathing pattern can help localize the lesion, but the examiner needs to be aware of potential pitfalls such as metabolic or pulmonary alterations. Methods We describe 3 cases in which central neurogenic respiratory failure occurred simultaneously with other alterations or in an unusual presentation. Results All patients were diagnosed with central neurogenic respiratory failure and tr...

  11. Transparency in Central Bank Financial Statement Disclosures

    OpenAIRE

    Kenneth Sullivan

    2000-01-01

    The IMF's development of the Code of Good Practices on Transparency in Monetary and Financial Policies and the introduction of safeguards assessments have increased emphasis on transparency of the disclosures made in central bank financial statements. This paper, which updates WP/00/186, looks at the disclosure requirements for central banks under International Financial Reporting Standards and provides practical guidance for those responsible for preparing central bank financial statements.

  12. On the Central Coefficients of Riordan Matrices

    OpenAIRE

    Barry, Paul

    2013-01-01

    We use the Lagrange-Bürmann inversion theorem to characterize the generating function of the central coefficients of the elements of the Riordan group of matrices. We apply this result to calculate the generating function of the central elements of a number of explicit Riordan arrays, defined by rational expressions, and in two cases we use the generating functions thus found to calculate the Hankel transforms of the central elements, which are themselves expressible as combinatorial polynomi...

  13. Clarity of Central Bank Communication About Inflation

    OpenAIRE

    Ales Bulir; David-Jan Jansen; Martin Cihak

    2011-01-01

    This paper examines whether the clarity of central bank communication about inflation has changed with the economic environment. We use readability statistics and content analysis to study the clarity of communication on the inflation outlook by seven central banks between 1997 and 2010. Overall, we find no strong indications that central banks were less clear in explaining their policies when faced with higher uncertainty or a less favorable inflation outlook. The global financial crisis, ho...

  14. 2. The Central American gang phenomenon

    OpenAIRE

    Does, Antonia

    2013-01-01

    2.1. Differentiating between pandillas and maras Youth gangs have existed since the 1960s and 1970s in Central America. However, there are different types of Central American gangs and thus one has to distinguish between pandillas and maras. The former are localized, homegrown gangs, which are “direct inheritors” (Jütersonke, Rodgers & Muggah 2009: 379) of the gangs that have historically characterized Central American societies, while the latter are a more recent phenomenon with transnationa...

  15. Urban history and modernity in Central Europe

    OpenAIRE

    Klautke, E. F.

    2010-01-01

    This historiographical review discusses recent literature on cities in modern Central Europe – mainly on Berlin and Vienna – which reflects the great variety of approaches to urban history and underlines the importance of urban history for the study of modernity. The history of urbanisation was a central event in the history of modernity. Especially in the Central European capitals of Berlin and Vienna, where modernisation and urban growth started later and then advanced quicker than in West ...

  16. Central nervous system tuberculosis: MRI

    International Nuclear Information System (INIS)

    The MRI findings of 18 proven cases of central nervous system (CNS) tuberculosis were reviewed; 10 patients were seropositive for HIV. All had medical, laboratory, or surgical proof of CNS tuberculosis. Eleven patients had meningitis, of whom two also had arachnoiditis. Five patients had focal intra-axial tuberculomas: four brain masses and one an intramedullary spinal lesion. Two patients had focal extra-axial tuberculomas: one in the pontine cistern, and one in the spine. In all 11 patients with meningitis MRI showed diffuse, thick, meningeal enhancement. All intraparenchymal tuberculomas showed low signal intensity on T2-weighted images and ring or nodular enhancement. The extra-axial tuberculomas had areas isointense or hypointense relative to normal brain and spinal cord on T2-weighted images. Although tuberculous meningitis cannot be differentiated from other meningitides on the basis of MR findings, intraparenchymal tuberculomas show characteristic T2 shortening, not found in most other space-occupying lesions. In the appropriate clinical setting, tuberculoma should be considered. (orig.)

  17. Towards a centralized Grid Speedometer

    CERN Document Server

    Gutsche, Oliver

    2013-01-01

    Given the distributed nature of the grid and the way CPU resources are pledged and scared around the globe, VOs are facing the challenge to monitor the use of these resources. For CMS and the operation of centralized workflows the monitoring of how many production jobs are running and pending in the Glidein WMS production pools is very important. The Dashboard SSB (Site Status Board) provides a very flexible framework to collect, aggregate and visualize data. The CMS production monitoring team uses the SSB to define the metrics that have to be monitored and the alarms that have to be set. During the integration of the CMS production monitoring into the SSB, several enhancements to the core functionality of the SSB were implemented; all in a generic way, so that other VOs using the SSB can use them as well. Alongside these enhancements, there were a few changes to the core of the SSB framework from which the CMS production team was able to benefit. We will present the details of the implementation and the adva...

  18. Towards a centralized Grid Speedometer

    Energy Technology Data Exchange (ETDEWEB)

    Dzhunov, I. [CERN; Andreeva, J. [CERN; Fajardo, E.; Gutsche, O.; Luyckx, S.; Saiz, P. [CERN

    2014-01-01

    Given the distributed nature of the Worldwide LHC Computing Grid and the way CPU resources are pledged and shared around the globe, Virtual Organizations (VOs) face the challenge of monitoring the use of these resources. For CMS and the operation of centralized workflows, the monitoring of how many production jobs are running and pending in the Glidein WMS production pools is very important. The Dashboard Site Status Board (SSB) provides a very flexible framework to collect, aggregate and visualize data. The CMS production monitoring team uses the SSB to define the metrics that have to be monitored and the alarms that have to be raised. During the integration of CMS production monitoring into the SSB, several enhancements to the core functionality of the SSB were required, They were implemented in a generic way, so that other VOs using the SSB can exploit them. Alongside these enhancements, there were a number of changes to the core of the SSB framework. This paper presents the details of the implementation and the advantages for current and future usage of the new features in SSB.

  19. Maximal switchability of centralized networks

    Science.gov (United States)

    Vakulenko, Sergei; Morozov, Ivan; Radulescu, Ovidiu

    2016-08-01

    We consider continuous time Hopfield-like recurrent networks as dynamical models for gene regulation and neural networks. We are interested in networks that contain n high-degree nodes preferably connected to a large number of N s weakly connected satellites, a property that we call n/N s -centrality. If the hub dynamics is slow, we obtain that the large time network dynamics is completely defined by the hub dynamics. Moreover, such networks are maximally flexible and switchable, in the sense that they can switch from a globally attractive rest state to any structurally stable dynamics when the response time of a special controller hub is changed. In particular, we show that a decrease of the controller hub response time can lead to a sharp variation in the network attractor structure: we can obtain a set of new local attractors, whose number can increase exponentially with N, the total number of nodes of the nework. These new attractors can be periodic or even chaotic. We provide an algorithm, which allows us to design networks with the desired switching properties, or to learn them from time series, by adjusting the interactions between hubs and satellites. Such switchable networks could be used as models for context dependent adaptation in functional genetics or as models for cognitive functions in neuroscience.

  20. A Central Theory of Biology

    Science.gov (United States)

    Torday, John S.

    2015-01-01

    The history of physiologic cellular–molecular interrelationships can be traced all the way back to the unicellular state by following the pathway formed by lipids ubiquitously accommodating calcium homeostasis, and its consequent adaptive effects on oxygen uptake by cells, tissues and organs. As a result, a cohesive, mechanistically integrated view of physiology can be formulated by recognizing the continuum comprising conception, development, physiologic homeostasis and death mediated by soluble growth factor signaling. Seeing such seemingly disparate processes as embryogenesis, chronic disease and dying as the gain and subsequent loss of cell–cell signaling provides a novel perspective for physiology and medicine. It is emblematic of the self-organizing, self-referential nature of life, starting from its origins. Such organizing principles obviate the pitfalls of teleologic evolution, conversely providing a way of resolving such seeming dichotomies as holism and reductionism, genotype and phenotype, emergence and contingence, proximate and ultimate causation in evolution, cells and organisms. The proposed approach is scale-free and predictive, offering a Central Theory of Biology. PMID:25911556

  1. The Centrality of Organization Design

    Directory of Open Access Journals (Sweden)

    Raymond E. Miles

    2012-05-01

    Full Text Available I am excited about this new journal focused on the subject of organization design. In my view, organization design is a central issue in the field of management. Designing an organization requires an understanding of strategy, as we pointed out some time ago (Miles & Snow, 1978. For example, if you want to be a prospector (a first-mover strategy, you have to design your firm to move quickly in new directions, which is likely to require that it be arranged so that various kinds of teams can interact across organizational units and levels. Designing an organization to follow a first-mover strategy also requires both an understanding of leadership and a commitment to the free flow of information throughout the organization. Leaders must understand how cross-functional teams pursue ideas and opportunities, and they must facilitate collaborative knowledge sharing to drive innovations that help the firm operate entrepreneurially. Because an organization is a complex, dynamic system, perhaps no other single topic is so deeply implanted at the core of management, organization theory, and organizational behavior as organization design. Moreover, organization design once was, and could be again, the topic of an ongoing dialogue between managers and academics focused on business organizations.

  2. Towards a centralized Grid Speedometer

    Science.gov (United States)

    Dzhunov, I.; Andreeva, J.; Fajardo, E.; Gutsche, O.; Luyckx, S.; Saiz, P.

    2014-06-01

    Given the distributed nature of the Worldwide LHC Computing Grid and the way CPU resources are pledged and shared around the globe, Virtual Organizations (VOs) face the challenge of monitoring the use of these resources. For CMS and the operation of centralized workflows, the monitoring of how many production jobs are running and pending in the Glidein WMS production pools is very important. The Dashboard Site Status Board (SSB) provides a very flexible framework to collect, aggregate and visualize data. The CMS production monitoring team uses the SSB to define the metrics that have to be monitored and the alarms that have to be raised. During the integration of CMS production monitoring into the SSB, several enhancements to the core functionality of the SSB were required; They were implemented in a generic way, so that other VOs using the SSB can exploit them. Alongside these enhancements, there were a number of changes to the core of the SSB framework. This paper presents the details of the implementation and the advantages for current and future usage of the new features in SSB.

  3. Towards a centralized Grid Speedometer

    International Nuclear Information System (INIS)

    Given the distributed nature of the Worldwide LHC Computing Grid and the way CPU resources are pledged and shared around the globe, Virtual Organizations (VOs) face the challenge of monitoring the use of these resources. For CMS and the operation of centralized workflows, the monitoring of how many production jobs are running and pending in the Glidein WMS production pools is very important. The Dashboard Site Status Board (SSB) provides a very flexible framework to collect, aggregate and visualize data. The CMS production monitoring team uses the SSB to define the metrics that have to be monitored and the alarms that have to be raised. During the integration of CMS production monitoring into the SSB, several enhancements to the core functionality of the SSB were required; They were implemented in a generic way, so that other VOs using the SSB can exploit them. Alongside these enhancements, there were a number of changes to the core of the SSB framework. This paper presents the details of the implementation and the advantages for current and future usage of the new features in SSB.

  4. A partitioned central solar receiver

    International Nuclear Information System (INIS)

    Else of solar energy as substitute for conventional fuels at a competitive cost requires efficient conversion from solar radiation to usable forms of energy. In solar thermal or thermochemical applications, high efficiency usually re- quires high temperature and high concentration of incoming radiation. The main form of energy loss from high temperature solar central receivers is thermal emission ('re radiation'), at an effective temperature close to the maximum receiver temperature. This loss is reduced if the aperture is divided into segments, most of which are maintained at lower temperatures. A two-stage partitioned receiver demonstrating this concept is under construction at the Weizman Solar Tower. The high-temperature stage is the DIAPR (Directly Irradiated Annular Pressurized Receiver). The low-temperature stage is made of tubular cavity receivers of simpler design. Preliminary optical and thermal design of the partitioned receiver is presented. For the design exit temperature of 1500 K, the aperture size of the partitioned receiver is about 60% of the equivalent single-stage receiver, indicating a significant increase of conversion efficiency. The exit temperature of the low-temperature stage is around 1100 K, allowing simpler design and inexpensive construction. (authors)

  5. A global central banker competency model

    Directory of Open Access Journals (Sweden)

    David W. Brits

    2014-02-01

    Full Text Available Orientation: No comprehensive, integrated competency model exists for central bankers. Due to the importance of central banks in the context of the ongoing global financial crisis, it was deemed necessary to design and validate such a model.Research purpose: To craft and validate a comprehensive, integrated global central banker competency model (GCBCM and to assess whether central banks using the GCBCM for training have a higher global influence.Motivation for the study: Limited consensus exists globally about what constitutes a ‘competent’ central banker. A quantitatively validated GCBCM would make a significant contribution to enhancing central banker effectiveness, and also provide a solid foundation for effective people management.Research approach, design and method: A blended quantitative and qualitative research approach was taken. Two sets of hypotheses were tested regarding the relationships between the GCBCM and the training offered, using the model on the one hand, and a central bank’s global influence on the other.Main findings: The GCBCM was generally accepted across all participating central banks globally, although some differences were found between central banks with higher and lower global influence. The actual training offered by central banks in terms of the model, however, is generally limited to technical-functional skills. The GCBCM is therefore at present predominantly aspirational. Significant differences were found regarding the training offered.Practical/managerial implications: By adopting the GCBCM, central banks would be able to develop organisation-specific competency models in order to enhance their organisational capabilities and play their increasingly important global role more effectively.Contribution: A generic conceptual framework for the crafting of a competency model with evaluation criteria was developed. A GCBCM was quantitatively validated.

  6. Digital data sets that describe aquifer characteristics of the Central Oklahoma aquifer in central Oklahoma

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set consists of digitized water-level elevation contours for the Central Oklahoma aquifer in central Oklahoma. This area encompasses all or part of...

  7. Digital data sets that describe aquifer characteristics of the Central Oklahoma aquifer in central Oklahoma

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set consists of digitized aquifer boundaries created for a previously published report about the Central Oklahoma aquifer in central Oklahoma. This area...

  8. Digital data sets that describe aquifer characteristics of the Central Oklahoma aquifer in central Oklahoma

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set consists of digitized polygons of a constant recharge value for the Central Oklahoma aquifer in central Oklahoma. This area encompasses all or part of...

  9. Digital data sets that describe aquifer characteristics of the Central Oklahoma aquifer in central Oklahoma

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set consists of digitized polygons of a constant hydraulic conductivity value for the Central Oklahoma aquifer in central Oklahoma. This area encompasses...

  10. Central bank independence and financial instability

    NARCIS (Netherlands)

    Klomp, J.G.; de Haan, J.

    2009-01-01

    It has been argued that central bank independence (CBI) may not only be beneficial for reaching the objective of price stability, but also for maintaining financial stability. Greater independence from external pressure implies that central banks are less politically constrained in acting to prevent

  11. International Regulation of Central Arctic Ocean Fisheries

    NARCIS (Netherlands)

    Molenaar, E.J.

    2016-01-01

    Due in particular to the impacts of climate change, the adequacy of the international regulation of Central Arctic Ocean fisheries has come under increasing scrutiny in recent years. As shown in this article, however, international regulation of Central Arctic Ocean fisheries is by no means entirely

  12. Nuclear Energy in Central Europe 98, Proceedings

    International Nuclear Information System (INIS)

    Regional Meeting for Nuclear Energy in Central Europe is an annual meeting of the Nuclear Society of Slovenia. The proceedings contain 63 articles from Slovenia, sorounding countries and countries of the Central and Eastern European Region. Topics are: Research Reactors, Nuclear Methods, Reactor Physics, Thermal Hydraulics, Structural Analysis, Probabilistic Safety Assessment, Severe Accidents, NPP Operation and Nuclear Waste disposal

  13. Visualizing the Central Limit Theorem through Simulation

    Science.gov (United States)

    Ruggieri, Eric

    2016-01-01

    The Central Limit Theorem is one of the most important concepts taught in an introductory statistics course, however, it may be the least understood by students. Sure, students can plug numbers into a formula and solve problems, but conceptually, do they really understand what the Central Limit Theorem is saying? This paper describes a simulation…

  14. The Cartan Matrix of a Centralizer Algebra

    Indian Academy of Sciences (India)

    Umesh V Dubey; Amritanshu Prasad; Pooja Singla

    2012-02-01

    The centralizer algebra of a matrix consists of those matrices that commute with it. We investigate the basic representation-theoretic invariants of centralizer algebras, namely their radicals, projective indecomposable modules, injective indecomposable modules, simple modules and Cartan matrices. With the help of our Cartan matrix calculations we determine their global dimensions. Many of these algebras are of infinite global dimension.

  15. The economic impact of central bank transparency

    NARCIS (Netherlands)

    van der Cruijsen, C.A.B.

    2008-01-01

    During the last decades a lot of central banks have become more transparent about their monetary policy. The research question that is addressed in this book is whether central bank transparency is desirable from an economic viewpoint. It is shown that transparency increases have been beneficial. Th

  16. The European Central Bank and financial supervision

    OpenAIRE

    Eijffinger, S.C.W.

    2004-01-01

    Analyzing ongoing changes in the design of regulatory and supervisory authorities over the banking and financial industry in Europe, this comprehensive Handbook pays particular attention to the role of national central banks, the new financial supervisory authorities and the European Central Bank (ECB).

  17. China-Central Asia Power Cooperation Outlook

    Institute of Scientific and Technical Information of China (English)

    Luo

    2010-01-01

    After analyzing the basic information,distribution of energy resources and condition of power industry in Central Asia, the high feasibility for China to cooperate closely with Central Asia in transnational power interconnection, power investment and technology exchanges, etc. is studied. Furthermore, the forms, mechanisms, existing problems and suggestions for the improvement of current policies related to the power cooperation are proposed.

  18. An unusual Complication of Central Venous Cannulation

    Directory of Open Access Journals (Sweden)

    Ashvini Kumar

    2013-04-01

    Full Text Available Central venous catheter (CVC hub fracture is a rare complication of central venous cannulation. We report a case where catheter hub fracture was detected immediately after CVC insertion. Causes of catheter hub fracture and its complications are discussed.

  19. Centralized rehabilitation after servere traumatic brain injury

    DEFF Research Database (Denmark)

    Engberg, Aase Worså; Liebach, Annette; Nordenbo, Annette Mosbæk

    2006-01-01

    OBJECTIVES: To present results from the first 3 years of centralized subacute rehabilitation after very severe traumatic brain injury (TBI), and to compare results of centralized versus decentralized rehabilitation. MATERIAL AND METHODS: Prospectively, the most severely injured group of adults from...

  20. A SCALED CENTRAL PATH FOR LINEAR PROGRAMMING

    Institute of Scientific and Technical Information of China (English)

    Ya-xiang Yuan

    2001-01-01

    Interior point methods are very efficient methods for solving large scale linear programming problems. The central path plays a very important role in interior point methods. In this paper we propose a new central path, which scales the variables. Thus it has the advantage of forcing the path to have roughly the same distance from each active constraint boundary near the solution.

  1. Traveling Policies: Hijacked in Central Asia

    Science.gov (United States)

    Silova, Iveta

    2005-01-01

    Since the collapse of the Soviet Union, Central Asian education reform discourses have become increasingly similar to distinctive Western policy discourses traveling globally across national boundaries. Tracing the trajectory of "traveling policies" in Central Asia, this article discusses the way Western education discourses have been hybridized…

  2. Novel central nervous system drug delivery systems.

    Science.gov (United States)

    Stockwell, Jocelyn; Abdi, Nabiha; Lu, Xiaofan; Maheshwari, Oshin; Taghibiglou, Changiz

    2014-05-01

    For decades, biomedical and pharmaceutical researchers have worked to devise new and more effective therapeutics to treat diseases affecting the central nervous system. The blood-brain barrier effectively protects the brain, but poses a profound challenge to drug delivery across this barrier. Many traditional drugs cannot cross the blood-brain barrier in appreciable concentrations, with less than 1% of most drugs reaching the central nervous system, leading to a lack of available treatments for many central nervous system diseases, such as stroke, neurodegenerative disorders, and brain tumors. Due to the ineffective nature of most treatments for central nervous system disorders, the development of novel drug delivery systems is an area of great interest and active research. Multiple novel strategies show promise for effective central nervous system drug delivery, giving potential for more effective and safer therapies in the future. This review outlines several novel drug delivery techniques, including intranasal drug delivery, nanoparticles, drug modifications, convection-enhanced infusion, and ultrasound-mediated drug delivery. It also assesses possible clinical applications, limitations, and examples of current clinical and preclinical research for each of these drug delivery approaches. Improved central nervous system drug delivery is extremely important and will allow for improved treatment of central nervous system diseases, causing improved therapies for those who are affected by central nervous system diseases.

  3. Guidance and Orientation Manual : Internal Diseases Ward 11 - Central Finland Central Hospital

    OpenAIRE

    Hirjaba, Marina

    2009-01-01

    The purpose of this Bachelor’s Thesis is to create an initiation manual for the foreign students, foreign visitors or anyone else interested about Internal Diseases ward 11, Central Finland Central Hospital. The aim of the guidance material is to help the foreign students, who are practicing on ward 11, to become acquainted with the Finnish Healthcare System, Central Finland Central Hospital and to offer orientation upon the nursing and organisation of Internal Diseases ward 11. It is taken i...

  4. Central station market development strategies for photovoltaics

    Science.gov (United States)

    1980-01-01

    Federal market development strategies designed to accelerate the market penetration of central station applications of photovoltaic energy system are analyzed. Since no specific goals were set for the commercialization of central station applications, strategic principles are explored which, when coupled with specific objectives for central stations, can produce a market development implementation plan. The study includes (1) background information on the National Photovoltaic Program, photovoltaic technology, and central stations; (2) a brief market assessment; (3) a discussion of the viewpoints of the electric utility industry with respect to solar energy; (4) a discussion of commercialization issues; and (5) strategy principles. It is recommended that a set of specific goals and objectives be defined for the photovoltaic central station program, and that these goals and objectives evolve into an implementation plan that identifies the appropriate federal role.

  5. Central station market development strategies for photovoltaics

    Science.gov (United States)

    1980-11-01

    Federal market development strategies designed to accelerate the market penetration of central station applications of photovoltaic energy system are analyzed. Since no specific goals were set for the commercialization of central station applications, strategic principles are explored which, when coupled with specific objectives for central stations, can produce a market development implementation plan. The study includes (1) background information on the National Photovoltaic Program, photovoltaic technology, and central stations; (2) a brief market assessment; (3) a discussion of the viewpoints of the electric utility industry with respect to solar energy; (4) a discussion of commercialization issues; and (5) strategy principles. It is recommended that a set of specific goals and objectives be defined for the photovoltaic central station program, and that these goals and objectives evolve into an implementation plan that identifies the appropriate federal role.

  6. Central registry in psychiatry: A structured review

    Directory of Open Access Journals (Sweden)

    Jyoti Prakash

    2014-01-01

    Full Text Available Background: Central registry in psychiatry is being practiced in few countries and has been found useful in research and clinical management. Role of central registry has also expanded over the years. Materials and Methods: All accessible internet database Medline, Scopus, Embase were accessed from 1990 till date. Available data were systematically reviewed in structured manner and analyzed. Results: Central registry was found useful in epidemiological analysis, association studies, outcome studies, comorbidity studies, forensic issue, effective of medication, qualitative analysis etc., Conclusion: Central registry proves to be effective tool in quantitative and qualitative understanding of psychiatry practice. Findings of studies from central registry can be useful in modifying best practice and evidence based treatment in psychiatry.

  7. Central differences, Euler numbers and symbolic methods

    CERN Document Server

    Dowker, J S

    2013-01-01

    I relate some coefficients encountered when computing the functional determinants on spheres to the central differentials of nothing. In doing this I use some historic works, in particular transcribing the elegant symbolic formalism of Jeffery (1861) into central difference form which has computational advantages for Euler numbers, as discovered by Shovelton (1915). I derive sum rules for these, and for the central differentials, the proof of which involves an interesting expression for powers of sech x as multiple derivatives. I present a more general, symbolic treatment of central difference calculus which allows known, and unknown, things to be obtained in an elegant and compact fashion gaining, at no cost, the expansion of the powers of the inverse sinh, a basic central function. Systematic use is made of the operator 2 asinh(D/2). Umbral calculus is employed to compress the operator formalism. For example the orthogonality/completeness of the factorial numbers, of the first and second kinds, translates, ...

  8. Reduced central blood volume in cirrhosis

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik; Bendtsen, Flemming; Sørensen, T I;

    1989-01-01

    was inversely correlated to the systemic vascular resistance (r = -0.49, p less than 0.001), the latter being significantly reduced in the patient group. Patients with cirrhosis apparently are unable to maintain a normal central blood volume. This may be due to arteriolar vasodilation, portosystemic collateral......The pathogenesis of ascites formation in cirrhosis is uncertain. It is still under debate whether the effective blood volume is reduced (underfilling theory) or whether the intravascular compartment is expanded (overflow theory). This problem has not yet been solved because of insufficient tools...... for measuring the central blood volume. We have developed a method that enables us to determine directly the central blood volume, i.e., the blood volume in the heart cavities, lungs, and central arterial tree. In 60 patients with cirrhosis and 16 control subjects the central blood volume was assessed according...

  9. The central curve in linear programming

    CERN Document Server

    De Loera, Jesús A; Vinzant, Cynthia

    2010-01-01

    The central curve of a linear program is an algebraic curve specified by linear and quadratic constraints arising from complementary slackness. It is the union of the various central paths for minimizing or maximizing the cost function over any region in the associated hyperplane arrangement. We determine the degree, arithmetic genus and defining prime ideal of the central curve, thereby answering a question of Bayer and Lagarias. These invariants, along with the degree of the Gauss image of the curve, are expressed in terms of the matroid of the input matrix. Extending work of Dedieu, Malajovich and Shub, this yields an instance-specific bound on the total curvature of the central path, a quantity relevant for interior point methods. The global geometry of central curves is studied in detail.

  10. Actual versus Perceived Central Bank Transparency : The Case of the European Central Bank

    NARCIS (Netherlands)

    van der Cruijsen, C.A.B.; Eijffinger, S.C.W.

    2007-01-01

    Central banks have become more and more transparent about their monetary policy making process. In the central bank transparency lit- erature the distinction between actual and perceived central bank trans- parency is often lacking. However, as perceptions are crucial for the ac- tions of economic a

  11. FROM CENTRAL ASIA TO GREAT CENTRAL ASIA: THE GOALS AND ADJUSTMENTS OF U.S. CENTRAL ASIAN STRATEGY

    OpenAIRE

    Tian, Robert

    2009-01-01

    To penetrate and maintain peaceful development of the Central Asian region is a consistent goal of the United States for its international interests. With the 9/11 event as the baseline, since 2001 America's awareness of the strategic importance of Central Asia and the latter's weight in U.S. global strategy has been greatly changed. According to Charles Manes, the 9/11 terrorist attack enabled the U.S. to "discover Central Asia. As a result of this discovery the United States effectively gai...

  12. XNAT Central: Open sourcing imaging research data.

    Science.gov (United States)

    Herrick, Rick; Horton, William; Olsen, Timothy; McKay, Michael; Archie, Kevin A; Marcus, Daniel S

    2016-01-01

    XNAT Central is a publicly accessible medical imaging data repository based on the XNAT open-source imaging informatics platform. It hosts a wide variety of research imaging data sets. The primary motivation for creating XNAT Central was to provide a central repository to host and provide access to a wide variety of neuroimaging data. In this capacity, XNAT Central hosts a number of data sets from research labs and investigative efforts from around the world, including the OASIS Brains imaging studies, the NUSDAST study of schizophrenia, and more. Over time, XNAT Central has expanded to include imaging data from many different fields of research, including oncology, orthopedics, cardiology, and animal studies, but continues to emphasize neuroimaging data. Through the use of XNAT's DICOM metadata extraction capabilities, XNAT Central provides a searchable repository of imaging data that can be referenced by groups, labs, or individuals working in many different areas of research. The future development of XNAT Central will be geared towards greater ease of use as a reference library of heterogeneous neuroimaging data and associated synthetic data. It will also become a tool for making data available supporting published research and academic articles.

  13. Central black hole masses of galaxies

    Institute of Scientific and Technical Information of China (English)

    樊军辉

    2003-01-01

    In this paper, the stellar velocity dispersions in the host galaxies are used to estimate the central black hole masses for a sample of elliptical galaxies. We find that the central black hole masses are in the range of 10(5.5-9.5) M(○). Based on the estimated masses in this paper and those by Woo & Urry (2002) and the measured host galaxy absolute magnitude,a relation, log(MBH/M(○)) = -(0.25 ± 4.3 × 10-3)MR + (2.98 4 0.208) is found for central black hole mass and the host galaxy magnitude. Some discussions are presented.

  14. Betweenness Centrality in Some Classes of Graphs

    Directory of Open Access Journals (Sweden)

    Sunil Kumar Raghavan Unnithan

    2014-01-01

    Full Text Available There are several centrality measures that have been introduced and studied for real-world networks. They account for the different vertex characteristics that permit them to be ranked in order of importance in the network. Betweenness centrality is a measure of the influence of a vertex over the flow of information between every pair of vertices under the assumption that information primarily flows over the shortest paths between them. In this paper we present betweenness centrality of some important classes of graphs.

  15. Central versus institutional self-archiving

    OpenAIRE

    Harnad, Stevan

    2006-01-01

    NIH's, PLoS's, the Wellcome Trust's and now the UK MRC's unreflective support for PubMed Central (PMC), a Central Repository (CR), as the locus for direct self-archiving by authors is very unfortunate for Institutional Repositories (IRs), for self-archiving, and for Open Access (OA) progress in general. Alma Swan has published key papers on both OA self-archiving policy and institutional versus central self-archiving (IRs vs. CRs) analysing the reasons. (a) Institutional self-archiving and ce...

  16. [Functional anatomy of the central nervous system].

    Science.gov (United States)

    Krainik, A; Feydy, A; Colombani, J M; Hélias, A; Menu, Y

    2003-03-01

    The central nervous system (CNS) has a particular regional functional anatomy. The morphological support of cognitive functions can now be depicted using functional imaging. Lesions of the central nervous system may be responsible of specific symptoms based on their location. Current neuroimaging techniques are able to show and locate precisely macroscopic lesions. Therefore, the knowledge of functional anatomy of the central nervous system is useful to link clinical disorders to symptomatic lesions. Using radio-clinical cases, we present the functional neuro-anatomy related to common cognitive impairments.

  17. Searchability of central nodes in networks

    CERN Document Server

    Klemm, Konstantin

    2013-01-01

    Social networks are discrete systems with a large amount of heterogeneity among nodes (individuals). Measures of centrality aim at a quantification of nodes' importance for structure and function. Here we ask to which extent the most central nodes can be found by purely local search. We find that many networks have close-to-optimal searchability under eigenvector centrality, outperforming searches for degree and betweenness. Searchability of the strongest spreaders in epidemic dynamics tends to be substantially larger for supercritical than for subcritical spreading.

  18. Francis Crick, DNA, and the Central Dogma

    Science.gov (United States)

    Olby, Robert

    1970-01-01

    This essay describes how Francis Crick, ex-physicist, entered the field of biology and discovered the structure of DNA. Emphasis is upon the double helix, the sequence hypothesis, the central dogma, and the genetic code. (VW)

  19. Miniaturized Airborne Imaging Central Server System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The innovation is a miniaturized airborne imaging central server system (MAICSS). MAICSS is designed as a high-performance computer-based electronic backend that...

  20. Miniaturized Airborne Imaging Central Server System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The innovation is a miniaturized airborne imaging central server system (MAICSS). MAICSS is designed as a high-performance-computer-based electronic backend that...

  1. Central Asian Snow Cover from Hydrometeorological Surveys

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Central Asian Snow Cover from Hydrometeorological Surveys data are based on observations made by personnel for three river basins: Amu Darya, Sir Darya, and...

  2. Veterans Affairs Central Cancer Registry (VACCR)

    Data.gov (United States)

    Department of Veterans Affairs — The Veterans Affairs Central Cancer Registry (VACCR) receives and stores information on cancer diagnosis and treatment constraints compiled and sent in by the local...

  3. Legume Diversity Patterns in West Central Africa

    NARCIS (Netherlands)

    Estrella, de la M.; Mateo, M.A.; Wieringa, J.J.; Mackinder, B.; Munoz, J.

    2012-01-01

    Objectives - Species Distribution Models (SDMs) are used to produce predictions of potential Leguminosae diversity in West Central Africa. Those predictions are evaluated subsequently using expert opinion. The established methodology of combining all SDMs is refined to assess species diversity withi

  4. Alluvial Boundary of California's Central Valley

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This digital dataset defines the extent of the alluvial deposits in the Central Valley of California and encompasses the contiguous Sacramento, San Joaquin, and...

  5. Central Gulf of Alaska Rockfish Permit Program

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The North Pacific Fishery Management Council adopted the Central Gulf of Alaska Rockfish Program (Rockfish Program) on June 14, 2010, to replace the expiring Pilot...

  6. New Neanurinae (Collembola: Neanuridae) from Central China.

    Science.gov (United States)

    Wang, Ya-Ru; Wang, Wen-Bin; Jiang, Jigang

    2016-01-01

    Three new species, two of Vitronura and one of Lobellina of subfamily Neanurinae (Neanuridae, Collembola) from Central China are described. In addition a key for valid Lobellina species is included. PMID:27470797

  7. Earthquakes in Central California, 1980-1984

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — There have been many earthquake occurrences in central California. This set of slides shows earthquake damage from the following events: Livermore, 1980, Coalinga,...

  8. Random walk centrality in interconnected multilayer networks

    Science.gov (United States)

    Solé-Ribalta, Albert; De Domenico, Manlio; Gómez, Sergio; Arenas, Alex

    2016-06-01

    Real-world complex systems exhibit multiple levels of relationships. In many cases they require to be modeled as interconnected multilayer networks, characterizing interactions of several types simultaneously. It is of crucial importance in many fields, from economics to biology and from urban planning to social sciences, to identify the most (or the less) influent nodes in a network using centrality measures. However, defining the centrality of actors in interconnected complex networks is not trivial. In this paper, we rely on the tensorial formalism recently proposed to characterize and investigate this kind of complex topologies, and extend two well known random walk centrality measures, the random walk betweenness and closeness centrality, to interconnected multilayer networks. For each of the measures we provide analytical expressions that completely agree with numerically results.

  9. California Black Rail - Central Delta [ds17

    Data.gov (United States)

    California Department of Resources — Results of taped-call black rail surveys of in-stream habitat within certain waterways in the central Sacramento / San Joaquin Delta during 1992 and 1993. TIME...

  10. Central Station DHC Phase 1 feasibility

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, H.L.

    1992-03-01

    This project assisted a private real estate developer in technically assessing the feasibility of integrating a central DHC system into a proposed 72 acre area mixed-use Planned Development (Central Station) just south of the Chicago Central Business District (Loop). The technical assessment concluded that a district heating and cooling system for Central Station will be feasible, provided that a major anchor load can be connected to the system. The system conceived for the site employs a modular approach that adjusts production capacity to actual load growth. The design concept includes gas-fired boilers for heating, gas turbine driven chillers for base loading, electric motor driven chillers for peaking, steam turbines for peak power and back pressure operation, and chilled water storage. Energy will be supplied to the users in the form of steam or low temperature hot water for heating, and low temperature chilled water for cooling.

  11. EXPLAINING TRAFFIC FLOW PATTERNS USING CENTRALITY MEASURES

    Directory of Open Access Journals (Sweden)

    Amila Jayasinghe

    2015-06-01

    Full Text Available This study examines the capability of centrality parameters of the road network to explain and predict traffic flow by types of vehicles. The case study was conducted in Colombo Metropolitan Area, Sri Lanka. Study used four centrality parameters i.e. connectivity, global integration, local integration and choice; and three analysis methods i.e. topological, metric and angular which introduced by space syntax analysis method to compute network centrality of the road network. Findings of this study stress that, (1 human beings perceive the space mostly from geometrical distance (topological and angular distance in comparison to metric distance. Further to this, it was found that angular distance is more powerful in global level whereas topological distance is more powerful in local level; (2 it is more appropriate to consider the multiple influences from multiple centrality parameters rather being confined to a single best parameter and influence of each parameter varies based on type of vehicles.

  12. NCPC Central Files Information System (CFIS)

    Data.gov (United States)

    National Capital Planning Commission — This dataset contains records from NCPC's Central Files Information System (CFIS), which is a comprehensive database of projects submitted to NCPC for design review...

  13. 1999 Yellow River Aerial Photos, Central Wisconsin

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The 25-mile stretch of the Yellow River adjacent to the Necedah National Wildlife Refuge in Central Wisconsin provides valuable habitat to numerous species of...

  14. Central California 3 arc-second DEM

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The 3-second Central California Elevation Grid provides bathymetric data in ASCII raster format of 3-second resolution in geographic coordinates. This grid is...

  15. Staging Childhood Central Nervous System Embryonal Tumors

    Science.gov (United States)

    ... children. See the PDQ summary on Adult Central Nervous System Tumors Treatment for more information on the treatment of adults. There are different types of CNS embryonal tumors. Enlarge Anatomy of the inside of the brain, showing the ...

  16. Initial TMX central-cell ICRH experiments

    International Nuclear Information System (INIS)

    Four topics are discussed in this report: the feasibility of applying ion cyclotron resonance heating (ICRH) in the TMX central cell, some applications of heating, the results of preliminary experiments, and plans for further ICRH experiments

  17. Entrapment of guidewire during central venous catheterization

    Directory of Open Access Journals (Sweden)

    Tarun S.

    2016-07-01

    Full Text Available Central venous catheterization (CVC is common in the setting of ICU for various reasons like monitoring of CVP, fluid administration and vasopressor or drug infusions. Guidewires are routinely used in the Seldinger technique during central venous catheter placement CVC placement is not innocuous as numerous complications may occur, with varying frequency and severity. [Int J Res Med Sci 2016; 4(7.000: 3080-3081

  18. Midwifery education in Central-Eastern Europe.

    Science.gov (United States)

    Mivšek, Polona; Baškova, Martina; Wilhelmova, Radka

    2016-02-01

    Problems in midwifery in many Central-Eastern European countries are very similar; it is possible to speak about the evolving Central-Eastern model of midwifery care. The educational models of this region have a relatively strong theoretical part; however, there is an insufficient practical dimension. Theoretical part of midwifery education in the universities is relatively autonomous and is slowly changing the professional identity of graduates. PMID:26632483

  19. Hitherto unreported Agaricus species of Central India

    OpenAIRE

    MAHENDRA KUMAR RAI; ALKA KARWA

    2010-01-01

    Karwa A, Rai MK. 2010. Hitherto unreported Agaricus species of Central India. Nusantara Bioscience 2: 141-145. Melghat forest region from Central India was surveyed for occurrence of medicinal and culinary mushrooms during the years 2005-2008. Out of total 153 species, ten species of Agaricus were recorded from different localities. Of these, seven species namely Agaricus bitorquis, A. subrufescens, A. augustus, A. placomyces, A. essettei, A. basioanolosus and Agaricus sp. nov (a new species)...

  20. Focal lesions in the central nervous system

    International Nuclear Information System (INIS)

    This report reviews the animal and human studies currently in progress at LBL with heavy-ion beams to induce focal lesions in the central nervous system, and discusses the potential future prospects of fundamental and applied brain research with heavy-ion beams. Methods are being developed for producing discrete focal lesions in the central nervous system using the Bragg ionization peak to investigate nerve pathways and neuroendocrine responses, and for treating pathological disorders of the brain

  1. Central Institute for Nuclear Research (1956 - 1979)

    International Nuclear Information System (INIS)

    The Central Institute for Nuclear Research (ZfK) of the Academy of Sciences of the GDR is presented. This first overall survey covers the development of the ZfK since 1956, the main research activities and results, a description of the departments responsible for the complex implementation of nuclear research, the social services for staff and the activities of different organizations in the largest central institute of the Academy of Sciences of the GDR. (author)

  2. Central diffractive resonance production at the LHC

    Science.gov (United States)

    Fiore, Roberto; Jenkovszky, Laszlo; Schicker, Rainer

    2016-07-01

    Central production of resonances resulting from the scattering of Pomerons in the central rapidity region of proton-proton scattering is studied. Estimates for relevant cross sections are presented. L.J. gratefully acknowledges an EMMI visiting Professorship at the University of Heidelberg for completion of this work. He is grateful to the organizers of this meeting for their hospitality and support. His work was supported also by DOMUS, Hungarian Academy of Sciences

  3. Central Asia's comparative advantage in international trade

    OpenAIRE

    Lücke, Matthias; Rothert, Jacek

    2006-01-01

    This paper outlines a strategy for identifying the pattern of Central Asia’s comparative advantage in international trade, based on factor prices and transport costs, historical production patterns, and recent trends in the geographical and product composition of Central Asian trade. The paper focuses on Kazakhstan, the Kyrgyz Republic, Tajikistan, and Uzbekistan, along with Azerbaijan and Mongolia. A country’s comparative advantage cannot be determined at the level of individual industries o...

  4. "Lessons from an Unconventional Central Banker"

    OpenAIRE

    Thorvald Grung Moe

    2013-01-01

    The global financial crisis has generated renewed interest in the 1951 Treasury - Federal Reserve Accord and its lessons for central bank independence. A broader interpretation of the Accord and of Marriner S. Eccles's role at the Federal Reserve should teach central bankers that independence can be crucial for fighting inflation, but also encourage them to be more supportive of government efforts to fight deflation and mass unemployment.

  5. Association and Centrality in Criminal Networks

    DEFF Research Database (Denmark)

    Petersen, Rasmus Rosenqvist

    and analyze the structural richness required to model and investigate criminal network entities and their associations. We demonstrate a need to rethink entity associations with one specific case (inspired by \\textit{The Wire}, a tv series about organized crime in Baltimore, United States) and corroborated...... three of these associations and extend and test two centrality measures using CrimeFighter Investigator, a novel tool for criminal network investigation. Our findings show that the extended centrality measures offer new insights into criminal networks....

  6. Role of Central Bank in Islamic Finance

    OpenAIRE

    Shaikh, Salman

    2009-01-01

    The rapid growth in Islamic finance industry urges us to not only look for alternatives in the Islamic commercial banking, but also focus on the regulator and its role and functions to enable it to work in conformity with Islamic principles. This study reviews limited, but precious academic literature on central banking and monetary management in an environment where Islamic finance is in vogue. Refinance ratio and Qard-e-Hasan ratio and Mudarabah between central bank and Islamic commercial b...

  7. Yes, we need a central bank

    OpenAIRE

    Hanif, Muhammad Nadim

    2002-01-01

    The financial system of a country comprises entities engaged in transactions involving financial instruments in money, capital, and foreign exchange markets. This sector has strong linkages with other sectors of the economy like external, fiscal and real sectors. The apex financial institution in every country is its Central Bank and the State Bank of Pakistan functions as our Central Bank. Section 9A. 1. of the State Bank of Pakistan Act 1956 shoulders the function of securing the soundness ...

  8. Peritoneal dissemination from central neurocytoma: case report

    OpenAIRE

    Coelho Neto Maurício; Ramina Ricardo; Meneses Murilo Sousa de; Arruda Walter Oleschko; Milano Jerônimo Buzetti

    2003-01-01

    OBJECTIVE: central neurocytoma is a low grade tumor of neuroglial origin and a relatively new histological entity. Only a few cases have been reported and its biological behavior is still uncertain. Some cases have shown an aggressive behavior (local recurrence, malignant dedifferentiation or CSF dissemination) and challenged the initial view of its relative benignity. A case of central neurocytoma with peritoneal dissemination is presented. CASE: a six years-old boy with recurrent neurocytom...

  9. The ultimate determinants of central bank independence

    OpenAIRE

    Eijffinger, S.C.W.; Schaling, E.

    1995-01-01

    Using a graphical method, a new way of determining the optimal degree of central bank conservativeness is developed in this paper. Unlike Lohmann (1992) and Rogoff (1985), we are able to express the upper and lower bounds of the interval containing the optimal degree of conservativeness in terms of the structural parameters of the model. Next, we show that optimal central bank independence is higher, the higher the natural rate of unemployment, the greater the benefits of unanticipated inflat...

  10. A handbook for solar central receiver design

    Energy Technology Data Exchange (ETDEWEB)

    Falcone, P.K.

    1986-12-01

    This Handbook describes central receiver technology for solar thermal power plants. It contains a description and assessment of the major components in a central receiver system configured for utility scale production of electricity using Rankine-cycle steam turbines. It also describes procedures to size and optimize a plant and discussed examples from recent system analyses. Information concerning site selection criteria, cost estimation, construction, and operation and maintenance is also included, which should enable readers to perform design analyses for specific applications.

  11. Central regions of keloids are severely ischaemic.

    Science.gov (United States)

    Touchi, Ryoma; Ueda, Koichi; Kurokawa, Norifumi; Tsuji, Motomu

    2016-02-01

    We classified scars as keloids, hypertrophic scars and mature scars, and then examined the scars for differences in central and marginal vascularization. We found significant differences in localized hypoxia-induced factor-1α (HIF-1α) expression and vascular density in keloids, but no localized differences in hypertrophic or mature scars. The central areas of keloids exhibited higher HIF-1α expression and lower vascular density than marginal areas, suggesting that the former are severely ischaemic. PMID:26794626

  12. De-centralized and centralized control for realistic EMS Maglev systems

    Science.gov (United States)

    Moawad, Mohamed M. Aly M.

    A comparative study of de-centralized and centralized controllers when used with real EMS Maglev Systems is introduced. This comparison is divided into two parts. Part I is concerned with numerical simulation and experimental testing on a two ton six-magnet EMS Maglev vehicle. Levitation and lateral control with these controllers individually and when including flux feedback control in combination with these controllers to enhance stability are introduced. The centralized controller is better than the de-centralized one when the system is exposed to a lateral disturbing force such as wind gusts. The flux feedback control when combined with de-centralized or centralized controllers does improve the stability and is more resistant and robust with respect to the air gap variations. Part II is concerned with the study of Maglev vehicle-girder dynamic interaction system and the comparison between these two controllers on this typical system based on performance and ride quality achieved. Numerical simulations of the ODU EMS Maglev vehicle interacting with girder are conducted with these two different controllers. The de-centralized and centralized control for EMS Maglev systems that interact with a flexible girder provides similar ride quality. Centralized control with flux feedback could be the best controller for the ODU Maglev system when operating on girder. The centralized control will guarantee the suppression of the undesired lateral displacements; hence it will provide smoother ride quality. Flux feedback will suppress air gap variations due to the track discontinuities.

  13. Central auditory function of deafness genes.

    Science.gov (United States)

    Willaredt, Marc A; Ebbers, Lena; Nothwang, Hans Gerd

    2014-06-01

    The highly variable benefit of hearing devices is a serious challenge in auditory rehabilitation. Various factors contribute to this phenomenon such as the diversity in ear defects, the different extent of auditory nerve hypoplasia, the age of intervention, and cognitive abilities. Recent analyses indicate that, in addition, central auditory functions of deafness genes have to be considered in this context. Since reduced neuronal activity acts as the common denominator in deafness, it is widely assumed that peripheral deafness influences development and function of the central auditory system in a stereotypical manner. However, functional characterization of transgenic mice with mutated deafness genes demonstrated gene-specific abnormalities in the central auditory system as well. A frequent function of deafness genes in the central auditory system is supported by a genome-wide expression study that revealed significant enrichment of these genes in the transcriptome of the auditory brainstem compared to the entire brain. Here, we will summarize current knowledge of the diverse central auditory functions of deafness genes. We furthermore propose the intimately interwoven gene regulatory networks governing development of the otic placode and the hindbrain as a mechanistic explanation for the widespread expression of these genes beyond the cochlea. We conclude that better knowledge of central auditory dysfunction caused by genetic alterations in deafness genes is required. In combination with improved genetic diagnostics becoming currently available through novel sequencing technologies, this information will likely contribute to better outcome prediction of hearing devices.

  14. Peripheral chemoreceptors in congenital central hypoventilation syndrome.

    Science.gov (United States)

    Perez, Iris A; Keens, Thomas G

    2013-01-01

    Congenital central hypoventilation syndrome is a rare disorder caused by a mutation in the PHOX2B gene resulting in hypoventilation that is worse during sleep. Human physiologic studies show that patients with CCHS have absent or decreased rebreathing ventilatory responses to hypercapnia and hypoxemia during sleep as well as during wakefulness. Some ventilatory responses to hypoxia and hyperoxia can be demonstrated using a step change in inspired oxygen. However, these suggest that both central and peripheral chemoreceptor functions are generally defective in all states in children with CCHS. The defect in CCHS may lie in central nervous system pathways regulating ventilation, whose development and function are controlled by PHOX2B. Moreover, the retrotrapezoid nucleus (RTN) may be the major defect in CCHS, where central and peripheral inputs converge. Human physiological studies predicted that the defect in CCHS lies in central integration of the central and peripheral chemoreceptor signals. New evidence suggests the RTN may be the respiratory controller where chemoreceptor inputs are integrated. In this review we present the clinical presentation of CCHS, revisit results of human physiologic studies, and discuss the findings in light of new knowledge about the role of PHOX2B and RTN in CCHS.

  15. Community centrality and social science research.

    Science.gov (United States)

    Allman, Dan

    2015-12-01

    Community centrality is a growing requirement of social science. The field's research practices are increasingly expected to conform to prescribed relationships with the people studied. Expectations about community centrality influence scholarly activities. These expectations can pressure social scientists to adhere to models of community involvement that are immediate and that include community-based co-investigators, advisory boards, and liaisons. In this context, disregarding community centrality can be interpreted as failure. This paper considers evolving norms about the centrality of community in social science. It problematises community inclusion and discusses concerns about the impact of community centrality on incremental theory development, academic integrity, freedom of speech, and the value of liberal versus communitarian knowledge. Through the application of a constructivist approach, this paper argues that social science in which community is omitted or on the periphery is not failed science, because not all social science requires a community base to make a genuine and valuable contribution. The utility of community centrality is not necessarily universal across all social science pursuits. The practices of knowing within social science disciplines may be difficult to transfer to a community. These practices of knowing require degrees of specialisation and interest that not all communities may want or have.

  16. Health challenges in Kazakhstan and Central Asia.

    Science.gov (United States)

    Adambekov, Shalkar; Kaiyrlykyzy, Aiym; Igissinov, Nurbek; Linkov, Faina

    2016-01-01

    The Central Asian region, which encompasses Kazakhstan, Uzbekistan, Tajikistan, Turkmenistan and Kyrgyzstan, is an interesting geographic region with a rich history dating back to the Silk Road, Mongol conquests and expansion of the Russian Empire. However, from a public health viewpoint, the Central Asian region is under-investigated, and many public health challenges exist, as countries of Central Asia inherited the centralised medical systems practiced in the Soviet Union, and are currently undergoing rapid transitions. A large number of low and middle-income countries around the world, including countries of Central Asia, face a double burden of chronic and infectious disease. This essay focuses on the exploration of the most important public health challenges in the Central Asian region, including limited scientific productivity, the double burden of chronic and infectious disease, the need for healthcare reform and the reduction in care variation. Central Asia has a large number of medical schools, medical centres, and emerging research institutes that can be used to foster a change in medical and public health practice in the region.

  17. Making Central Banks Serve The Real Economy

    Directory of Open Access Journals (Sweden)

    Suleika Reiners

    2013-10-01

    Full Text Available The challenge is to redirect central bank money into the real economy and to the needs of society. If new money is issued to expand the productive capacity, there is no reason for inflation. Long-term financing could become available at an affordable price. Central bank money must not replace a sound tax system and the distribution of income and wealth, but complement them. The remaining task, apart from the financing of real needs, is the prevention of speculative asset price inflation. For this, central banks and regulators should install debt brakes for the financial sector. Furthermore, independent monetary policy calls for capital account management. It enables national central banks to find space for the conduct of their own policies in an interdependent global economy. Coordination between central banks and governments might increase as policies combine monetary, fiscal and regulatory facets. The future role of central banks should particularly lie in their insights regarding capital flows and leverage cycles and in their ability to create and withdraw money, depend­ing on economic conditions.

  18. Community centrality and social science research.

    Science.gov (United States)

    Allman, Dan

    2015-12-01

    Community centrality is a growing requirement of social science. The field's research practices are increasingly expected to conform to prescribed relationships with the people studied. Expectations about community centrality influence scholarly activities. These expectations can pressure social scientists to adhere to models of community involvement that are immediate and that include community-based co-investigators, advisory boards, and liaisons. In this context, disregarding community centrality can be interpreted as failure. This paper considers evolving norms about the centrality of community in social science. It problematises community inclusion and discusses concerns about the impact of community centrality on incremental theory development, academic integrity, freedom of speech, and the value of liberal versus communitarian knowledge. Through the application of a constructivist approach, this paper argues that social science in which community is omitted or on the periphery is not failed science, because not all social science requires a community base to make a genuine and valuable contribution. The utility of community centrality is not necessarily universal across all social science pursuits. The practices of knowing within social science disciplines may be difficult to transfer to a community. These practices of knowing require degrees of specialisation and interest that not all communities may want or have. PMID:26440071

  19. Systemic 5-Bromo-2-Deoxyuridine Induces Conditioned Flavor Aversion and C-Fos in the Visceral Neuraxis

    Science.gov (United States)

    Kimbrough, Adam; Kwon, Bumsup; Eckel, Lisa A.; Houpt, Thomas A.

    2011-01-01

    5-bromo-2-deoxyuridine (BrdU) is often used in studies of adult neurogenesis and olfactory learning, but it can also have toxic effects on highly proliferative tissue. We found that pairing Kool-Aid flavors with acute systemic injections of BrdU induced strong conditioned flavor aversions. Intermittent injections during Kool-Aid-glucose…

  20. Anesthetic management of super-morbidly obese parturients for cesarean delivery with a double neuraxial catheter technique: a case series.

    Science.gov (United States)

    Polin, C M; Hale, B; Mauritz, A A; Habib, A S; Jones, C A; Strouch, Z Y; Dominguez, J E

    2015-08-01

    Parturients with super-morbid obesity, defined as body mass index greater than 50kg/m(2), represent a growing segment of patients who require anesthetic care for labor and delivery. Severe obesity and its comorbid conditions place the parturient and fetus at greater risk for pregnancy complications and cesarean delivery, as well as surgical and anesthetic complications. The surgical approach for cesarean delivery in these patients may require a supra-umbilical vertical midline incision due to a large pannus. The dense T4-level of spinal anesthesia can cause difficulties with ventilation for the obese patient during the procedure, which can be prolonged. Patients also may have respiratory complications in the postoperative period due to pain from the incision. We describe the anesthetic management of three parturients with body mass index ranging from 73 to 95kg/m(2) who had a cesarean delivery via a supra-umbilical vertical midline incision. Continuous lumbar spinal and low thoracic epidural catheters were placed in each patient for intraoperative anesthesia and postoperative analgesia, respectively. Continuous spinal catheters were dosed with incremental bupivacaine boluses to achieve surgical anesthesia. In one case, the patient required respiratory support with non-invasive positive pressure ventilation. Two cases were complicated by intraoperative hemorrhage. All patients had satisfactory postoperative analgesia with a thoracic epidural infusion. None suffered postoperative respiratory complications or postdural puncture headache. The use of a continuous lumbar spinal catheter and a low thoracic epidural provides several advantages in the anesthetic management of super-morbidly obese parturients for cesarean delivery.

  1. Market Information and Signaling in Central Bank Operations, or, How Often Should a Central Bank Intervene?

    OpenAIRE

    International Monetary Fund

    1997-01-01

    A central bank must decide on the frequency with which it will conduct open market operations and the variability in short-term money market that it will allow. The paper shows how the optimal operating procedure balances the value of attaining an immediate target and broadcasting the central bank's intentions against the informational advantages to the central bank of allowing the free play of market forces to reveal more of the information available to market participants.

  2. Central Banker Contracts, Incomplete Information, and Monetary Policy Surprises: In Search of a Selfish Central Banker?

    OpenAIRE

    Georgios E. Chortareas; Miller, Stephen M.

    2002-01-01

    Approaching monetary policy as a principal agent problem provides a useful framework for interpreting alternative delegation schemes. In this paper, we consider the effectiveness of central banker incentive schemes when the principal delegates monetary policy through contracts but remains uncertain about the central banker's responsiveness to such schemes. We adopt a simple principal-agent model and assume that the central banker's trade-off between social welfare and the incentive scheme is ...

  3. Central nervous system complications after liver transplantation.

    Science.gov (United States)

    Kim, Jeong-Min; Jung, Keun-Hwa; Lee, Soon-Tae; Chu, Kon; Roh, Jae-Kyu

    2015-08-01

    We investigated the diversity of central nervous system complications after liver transplantation in terms of clinical manifestations and temporal course. Liver transplantation is a lifesaving option for end stage liver disease patients but post-transplantation neurologic complications can hamper recovery. Between 1 January 2001 and 31 December 2010, patients who had undergone liver transplantation at a single tertiary university hospital were included. We reviewed their medical records and brain imaging data and classified central nervous system complications into four categories including vascular, metabolic, infectious and neoplastic. The onset of central nervous system complications was grouped into five post-transplantation intervals including acute (within 1 month), early subacute (1-3 months), late subacute (3-12 months), chronic (1-3 years), and long-term (after 3 years). During follow-up, 65 of 791 patients (8.2%) experienced central nervous system complications, with 30 occurring within 1 month after transplantation. Vascular etiology was the most common (27 patients; 41.5%), followed by metabolic (23; 35.4%), infectious (nine patients; 13.8%), and neoplastic (six patients). Metabolic encephalopathy with altered consciousness was the most common etiology during the acute period, followed by vascular disorders. An initial focal neurologic deficit was detected in vascular and neoplastic complications, whereas metabolic and infectious etiologies presented with non-focal symptoms. Our study shows that the etiology of central nervous system complications after liver transplantation changes over time, and initial symptoms can help to predict etiology.

  4. Correcting intermittent central suppression improves binocular marksmanship.

    Science.gov (United States)

    Hussey, Eric S

    2007-04-01

    Intermittent central suppression (ICS) is a defect in normal binocular (two-eyed) vision that causes confusion in visual detail. ICS is a repetitive intermittent loss of visual sensation in the central area of vision. As the central vision of either eye "turns on and off", aiming errors in sight can occur that must be corrected when both eyes are seeing again. Any aiming errors in sight might be expected to interfere with marksmanship during two-eyed seeing. We compared monocular (one-eyed, patched) and binocular (two-eyed) marksmanship with pistol shooting with an Army ROTC cadet before and after successful therapy for diagnosed ICS. Pretreatment, monocular marksmanship was significantly better than binocular marksmanship, suggesting defective binocularity reduced accuracy. After treatment for ICS, binocular and monocular marksmanship were essentially the same. Results confirmed predictions that with increased visual stability from correcting the suppression, binocular and monocular marksmanship accuracies should merge. PMID:17484315

  5. Generation of central exclusive final states

    CERN Document Server

    Lönnblad, Leif

    2016-01-01

    We present a scheme for the generation of central exclusive final states in the Pythia 8 program. The implementation allows for the investigation of higher order corrections to such exclusive processes as approximated by the initial-state parton shower in Pythia 8. To achieve this, the spin and colour decomposition of the initial-state shower has been worked out, in order to determine the probability that a partonic state generated from an inclusive sub-process followed by a series of initial-state parton splittings can be considered as an approximation of an exclusive colour- and spin-singlet process. We use our implementation to investigate effects of parton showers on some examples of central exclusive processes, and find sizeable effects on di-jet production, while the effects on e.g. central exclusive Higgs production are minor.

  6. Estimation for large non-centrality parameters

    Science.gov (United States)

    Inácio, Sónia; Mexia, João; Fonseca, Miguel; Carvalho, Francisco

    2016-06-01

    We introduce the concept of estimability for models for which accurate estimators can be obtained for the respective parameters. The study was conducted for model with almost scalar matrix using the study of estimability after validation of these models. In the validation of these models we use F statistics with non centrality parameter τ =‖λ/‖2 σ2 when this parameter is sufficiently large we obtain good estimators for λ and α so there is estimability. Thus, we are interested in obtaining a lower bound for the non-centrality parameter. In this context we use for the statistical inference inducing pivot variables, see Ferreira et al. 2013, and asymptotic linearity, introduced by Mexia & Oliveira 2011, to derive confidence intervals for large non-centrality parameters (see Inácio et al. 2015). These results enable us to measure relevance of effects and interactions in multifactors models when we get highly statistically significant the values of F tests statistics.

  7. Central pain: definition, phisiopathology and therapy

    Directory of Open Access Journals (Sweden)

    Vincenzo Moschini

    2012-12-01

    Full Text Available Central pain is the expression of an injury and/or a primary or secondary dysfunction of the central nervous system.1 It is based on total or partial damage along the spinal-thalamic-cortical pathways and it may have cerebral or spinal origin. It has variable incidence according to its etiology: 8-10% in stroke patients, 30% in multiple sclerosis patients, 30-60% in paraplegic patients.2-3 At the spinal level, the most frequent causes are: traumatic injuries, cancer, plaques from multiple sclerosis, syringomyelia. In this review, we examine the main symptoms that contribute to confirm the diagnosis of central pain, neuropathic or thalamic. The presence of nerve injury, evaluated by neuroimaging and neurophysiological tests, allows us to complete the diagnostic picture.

  8. Central functions of the orexinergic system

    Institute of Scientific and Technical Information of China (English)

    Xiao-Yang Zhang; Lei Yu; Qian-Xing Zhuang; Jing-Ning Zhu; Jian-Jun Wang

    2013-01-01

    The neuropeptide orexin is synthesized by neurons exclusively located in the hypothalamus.However,these neurons send axons over virtually the entire brain and spinal cord and therefore constitute a unique central orexinergic system.It is well known that central orexin plays a crucial role in the regulation of various basic non-somatic and somatic physiological functions,including feeding,energy homeostasis,the sleep/wake cycle,reward,addiction,and neuroendocrine,as well as motor control.Moreover,the absence of orexin results in narcolepsy-cataplexy,a simultaneous somatic and non-somatic dysfunction.In this review,we summarize these central functions of the orexinergic system and associated diseases,and suggest that this system may hold a key position in somatic-non-somatic integration.

  9. Dry needling - peripheral and central considerations.

    Science.gov (United States)

    Dommerholt, Jan

    2011-11-01

    Dry needling is a common treatment technique in orthopedic manual physical therapy. Although various dry needling approaches exist, the more common and best supported approach targets myofascial trigger points. This article aims to place trigger point dry needling within the context of pain sciences. From a pain science perspective, trigger points are constant sources of peripheral nociceptive input leading to peripheral and central sensitization. Dry needling cannot only reverse some aspects of central sensitization, it reduces local and referred pain, improves range of motion and muscle activation pattern, and alters the chemical environment of trigger points. Trigger point dry needling should be based on a thorough understanding of the scientific background of trigger points, the differences and similarities between active and latent trigger points, motor adaptation, and central sensitize application. Several outcome studies are included, as well as comments on dry needling and acupuncture.

  10. Retail Market Structure Development in Central Europe

    Directory of Open Access Journals (Sweden)

    Martin Machek

    2012-12-01

    Full Text Available This article is analyzing the trends and development in the retailing sector in Central Europe, namely in the Czech Republic, Hungary, Poland and Slovakia. These markets serve about 63 million inhabitants. The retail industry in Central Europe has changed dramatically in the last two decades, and has become a model for successful transformation of emerging markets. The retail market is highly concentrated and dominated by Western European retail chains. International retail chains are using all formats of modern distribution. This article is focusing on the development of hypermarkets, supermarkets and discount stores. Due to the international retail chains, Central European countries benefit from a dense network of modern shopping places; the intense competition of highly productive retailers contributes to the lower level of inflation rate because of the so-called Wal-Mart Effect. The constant pressure on prices influences the marketing strategies of both retailers and suppliers.

  11. Hydrogels for central nervous system therapeutic strategies.

    Science.gov (United States)

    Russo, Teresa; Tunesi, Marta; Giordano, Carmen; Gloria, Antonio; Ambrosio, Luigi

    2015-12-01

    The central nervous system shows a limited regenerative capacity, and injuries or diseases, such as those in the spinal, brain and retina, are a great problem since current therapies seem to be unable to achieve good results in terms of significant functional recovery. Different promising therapies have been suggested, the aim being to restore at least some of the lost functions. The current review deals with the use of hydrogels in developing advanced devices for central nervous system therapeutic strategies. Several approaches, involving cell-based therapy, delivery of bioactive molecules and nanoparticle-based drug delivery, will be first reviewed. Finally, some examples of injectable hydrogels for the delivery of bioactive molecules in central nervous system will be reported, and the key features as well as the basic principles in designing multifunctional devices will be described.

  12. 75 FR 14436 - Ameren Corporation, Illinois Power Company, Central Illinois Light Company, Central Illinois...

    Science.gov (United States)

    2010-03-25

    ... Energy Regulatory Commission Ameren Corporation, Illinois Power Company, Central Illinois Light Company, Central Illinois Public Service Company, Ameren Energy Resources Company, LLC, AmerenEnergy Resources Generating Company; Notice of Filing March 18, 2010. Take notice that on March 15, 2010, Ameren...

  13. Actual versus perceived central bank transparency: the case of the European Central Bank

    NARCIS (Netherlands)

    C. van der Cruijsen; S. Eijffinger

    2008-01-01

    Central banks have become more and more transparent about their monetary policy making process. In the central bank transparency literature the distinction between actual and perceived transparency is often lacking. However, as perceptions are crucial for the actions of economic agents this distinct

  14. The primary Maxillary Central Incisor in the Solitary Median Maxillary Central Incisor syndrome

    DEFF Research Database (Denmark)

    Kjaer, I; Balslev-Olesen, M

    2012-01-01

    Solitary Median Maxillary Central Incisor (SMMCI) is a developmental anomaly in the permanent dentition with one single central incisor in the maxilla, positioned exactly in the midline. This condition has been associated with extra- and intraoral malformations in the frontonasal segment of the c...

  15. Solitary median maxillary central incisor (SMMCI) syndrome

    OpenAIRE

    Hall Roger K

    2006-01-01

    Abstract Solitary median maxillary central incisor syndrome (SMMCI) is a complex disorder consisting of multiple, mainly midline defects of development resulting from unknown factor(s) operating in utero about the 35th–38th day(s) from conception. It is estimated to occur in 1:50,000 live births. Aetiology is uncertain. Missense mutation in the SHH gene (I111F) at 7q36 may be associated with SMMCI. The SMMCI tooth differs from the normal central incisor, in that the crown form is symmetric; i...

  16. [Centralization in obstetrics: pros and cons].

    Science.gov (United States)

    Roemer, V M; Ramb, S

    1996-01-01

    Possible advantages and disadvantages of a general centralization of German obstetric facilities are analysed in the study. The need for centralization of risk cases, especially premature births (regionalization) is pointed out. Centralization appears appropriate, since every fifth maternity unit in Germany (19.78%) has 300 or fewer deliveries per year. This one fifth of perinatal clinics accounts for 6.3% of all deliveries (N = 49450). There are appreciable differences between the old and new federal states (Bundesländer): in the recently acceded federal states, 48.7% of all perinatal clinics have deliveries of 300 and less per year. This group of perinatal clinics accounts for 29% of all deliveries in the new federal states. We have carried out a survey of the mother's attitude to centralization: out of 416 patients in the Detmold women's hospital whose mean age was 29.0 +/- 4.2 years, 90.4% were not in favor of general centralization of obstetrics. 43% were also against a centralization of risk cases (regionalization). 75% of the women surveyed objected to centralized obstetrics because of the 'possible absence of the family', the 'possible absence of students and trainees' (44.9%), the 'unfamiliarity with staff and premises' (41.8%) and 'fear of anonymity' (44.5%). The majority of all women (84.1%) did not want to have a drive more than 20 km to an obstetrics center. Fear of 'delivery in a taxi'(78.6%), the 'fear that the husband will come too late to the delivery' (65.4%) and that the 'overall course of the delivery might not be adequate for reasons of time'. The presence of a pediatrics department in conjunction with the perinatal clinic was rated very positively (93%). It is concluded from the data and further juridical considerations that centralization of risk cases (regionalization) is indispensable in the near future and that somewhat more further into the future decentralization should be carried out by closing obstetrics departments with substantially

  17. MRI of central nervous system anomalies

    Energy Technology Data Exchange (ETDEWEB)

    Izawa, M.; Oikawa, A.; Matoba, A.

    1987-05-01

    MRI was very useful in the evaluation of congenital anomalies of central nervous system as well as other nervous system disease with three-dimensional spatial resolution. We had experienced MRI of central nervous system anomalies, demonstrated characterisitic findings in each anomaly. MRI is useful to observe the coronal, horizontal and sagittal images of the brain and spinal cord in order to discuss the etiological mechanisms of spinal dysraphysm and its associated anomalies. In case of spina bifida cystica MRI was available to decide operative indication for radical operation and tetherd cord developed from postoperative scar or accompanied intraspinal lesions.

  18. Simulating central forces in the classroom

    CERN Document Server

    Aguirregabiria, Juan M

    2015-01-01

    We describe the easy to customize and extend open source Java program Central force workbench that can be used in the classroom to simulate the motion of a particle (or a two-body system) under central forces. It may be useful to illustrate problems in which the analytical solution is not available as well as to help students to grasp a more intuitive understanding of the main features of this kind of problem and to realize the exceptional nature of the particular case of Newtonian (and harmonic) forces. We also include some suggestions on how to use the program as a pedagogical tool.

  19. Incoerenza temporale e indipendenza della banca centrale

    Directory of Open Access Journals (Sweden)

    Bruno Jossa

    2012-04-01

    Full Text Available According to the author, the emphasis authors currently tend to place on the 'surprise effect' in order to argue for the independence of central banks is to a large extent unjustified. The main arguments for the independence of a cen-tral bank are others: firstly, the opinion that governments are induced to in-cur excessive expenditure due to reasons highlighted by public choice theo-rists and, secondly, the idea that inflation arises in connection with social conflict. Additionally, this study makes it clear that 'time inconsistency' theory is far from being a new way of stating old ideas.  JEL Codes: E58Keywords:

  20. MRI of central nervous system anomalies

    International Nuclear Information System (INIS)

    MRI was very useful in the evaluation of congenital anomalies of central nervous system as well as other nervous system disease with three-dimensional spatial resolution. We had experienced MRI of central nervous system anomalies, demonstrated characterisitic findings in each anomaly. MRI is useful to observe the coronal, horizontal and sagittal images of the brain and spinal cord in order to discuss the etiological mechanisms of spinal dysraphysm and its associated anomalies. In case of spina bifida cystica MRI was available to decide operative indication for radical operation and tetherd cord developed from postoperative scar or accompanied intraspinal lesions. (author)

  1. Central helium density measurements in PLT

    International Nuclear Information System (INIS)

    The central helium density in PLT has been deduced from measurements of the ratio of d-3He to d-d fusion reactions during deuterium neutral beam injection. The inward transport time for 3He puffed at the edge plasma was 10 → 30 msec. The decay time of the central 3He density increased with electron density, varying from 0.3 sec to greater than 1.0 sec over the density range of (1 → 5) x 1013 cm-3

  2. Centralized surveillance and control of satellite networks

    Science.gov (United States)

    Rzewnicki, S. E.; McBeath, J. W.; Brostrup-Jensen, P.

    Satellite based services and networks are increasing in number. This paper describes how such networks can be operated efficiently using software based systems to do satellite transmission surveillance and remote earth station status, alarm and control monitoring at a centralized operations control center. Arrangements are available to accomplish real time, customer controlled configuration of space segments and earth station equipment. Application of the system elements satellite transmission surveillance, alarm and control central, earth station remote, and customer control terminals - to a number of typical networks is described.

  3. Centralized vs. Distributed Databases. Case Study

    Directory of Open Access Journals (Sweden)

    Nicoleta Magdalena Iacob

    2015-12-01

    Full Text Available Currently, in information technology domain and implicit in databases domain can be noticed two apparently contradictory approaches: centralization and distribution respectively. Although both aim to produce some benefits, it is a known fact that for any advantage a price must be paid. In addition, in this paper we have presented a case study, e-learning portal performance optimization by using distributed databases technology. In the stage of development in which institutions have branches distributed over a wide geographic area, distributed database systems become more appropriate to use, because they offer a higher degree of flexibility and adaptability then centralized ones.

  4. Centralized rehabilitation after servere traumatic brain injury

    DEFF Research Database (Denmark)

    Engberg, Aase Worså; Liebach, Annette; Nordenbo, Annette Mosbæk

    2006-01-01

    OBJECTIVES: To present results from the first 3 years of centralized subacute rehabilitation after very severe traumatic brain injury (TBI), and to compare results of centralized versus decentralized rehabilitation. MATERIAL AND METHODS: Prospectively, the most severely injured group of adults from...... an uptake area of 2.4 million in Denmark were included at admission to a regional brain injury unit (BIU), on average 19 days after injury. Patients in the retrospective study used for comparison were randomly chosen from the national hospital register. RESULTS AND CONCLUSIONS: Out of 117 patients...

  5. Metabolic syndrome and central retinal artery occlusion

    OpenAIRE

    Kosanović-Jaković Natalija; Petrović Lidija; Risimić Dijana; Milenković Svetislav; Matić Danica

    2005-01-01

    Background. The accumulation of risk factors for central retinal artery occlusion can be seen in a single person and might be explained by the metabolic syndrome. Case report. We presented the case of a 52-year-old man with no light perception in his right eye. The visual loss was monocular and painless, fundoscopy showed central retinal artery occlusion and the laboratory investigation showed the raised erythrocyte sedimentation rate of 105 mm/h and the raised C-reactive protein of 22 mg/l. ...

  6. Probabilistic seismic hazard assessment for Central Asia

    OpenAIRE

    Shahid Ullah; Dino Bindi; Marco Pilz; Laurentiu Danciu; Graeme Weatherill; Elisa Zuccolo; Anatoly Ischuk; Natalya N. Mikhailova; Kanat Abdrakhmatov; Stefano Parolai

    2015-01-01

    Central Asia is one of the seismically most active regions in the world. Its complex seismicity due to the collision of the Eurasian and Indian plates has resulted in some of the world’s largest intra-plate events over history. The region is dominated by reverse faulting over strike slip and normal faulting events. The GSHAP project (1999), aiming at a hazard assessment on a global scale, indicated that the region of Central Asia is characterized by peak ground accelerations for 10% probabili...

  7. Progress in ATLAS central solenoid magnet

    CERN Document Server

    Yamamoto, A; Makida, Y; Tanaka, K; Haruyama, T; Yamaoka, H; Kondo, T; Mizumaki, S; Mine, S; Wada, K; Meguro, S; Sotoki, T; Kikuchi, K; ten Kate, H H J

    2000-01-01

    The ATLAS central solenoid magnet is being developed to provide a magnetic field of 2 Tesla in the central tracking volume of the ATLAS detector under construction at the CERN/LHC project. The solenoid coil design features high-strength aluminum stabilized superconductor to make the coil thinnest while maintaining its stability and the pure-aluminum strip technique for quench protection and safety. The solenoid coil is installed in a common cryostat with the LAr calorimeter in order to minimize the cryostat wall. A transparency of 0.66 radiation length is achieved with these integrated efforts. The progress in the solenoid coil fabrication is reported. (8 refs).

  8. The Boolean algebra and central Galois algebras

    Directory of Open Access Journals (Sweden)

    George Szeto

    2001-01-01

    Full Text Available Let B be a Galois algebra with Galois group G, Jg={b∈B∣bx=g(xb   for all   x∈B} for g∈G, and BJg=Beg for a central idempotent eg. Then a relation is given between the set of elements in the Boolean algebra (Ba,≤ generated by {0,eg∣g∈G} and a set of subgroups of G, and a central Galois algebra Be with a Galois subgroup of G is characterized for an e∈Ba.

  9. Church Orientations in Central and Eastern Europe

    Science.gov (United States)

    Laužikas, Rimvydas

    The objective of this case study is to discuss church orientation in Central and Eastern Europe. Due to its geographical situation, this region is a specific part of European cultural space: it is remote from the main cultural centers, it was the last to adopt Christianity, and it experienced intensive interactions with Byzantine culture. Therefore, we can assess church orientation in Central and Eastern Europe as a tradition affected by multicultural interactions and in which there is an interlacement of Catholicism from Western Europe, Byzantinism, local pagan faiths and, in part, the ideas of conception of geographical space of the Jews, Karaites, and Muslims.

  10. China-Central Asia Friendship Association Founded

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>The China-Central Asia Friendship Association(CCAFA) held its inaugural meeting in Beijing on December 18,2007. The CCAFA,founded at the initiation of the CPAFFC,is a national non-profit social organization with legal person status.It aims to further expand people-to-people contact between China and the five Central Asian countries,namely Kazakhstan,Kirghizstan,Tajikistan,Turkmenistan and Uzbekistan,enhance regional cooperation and deepen good-neighbourly relations so as to consolidate the social foundation for lasting friendship between China and these countries and promote common development.

  11. Computing betweenness centrality in external memory

    DEFF Research Database (Denmark)

    Arge, Lars; Goodrich, Michael T.; Walderveen, Freek van

    2013-01-01

    Betweenness centrality is one of the most well-known measures of the importance of nodes in a social-network graph. In this paper we describe the first known external-memory and cache-oblivious algorithms for computing betweenness centrality. We present four different external-memory algorithms...... exhibiting various tradeoffs with respect to performance. Two of the algorithms are cache-oblivious. We describe general algorithms for networks with weighted and unweighted edges and a specialized algorithm for networks with small diameters, as is common in social networks exhibiting the “small worlds...

  12. Centrality measures for networks with community structure

    Science.gov (United States)

    Gupta, Naveen; Singh, Anurag; Cherifi, Hocine

    2016-06-01

    Understanding the network structure, and finding out the influential nodes is a challenging issue in large networks. Identifying the most influential nodes in a network can be useful in many applications like immunization of nodes in case of epidemic spreading, during intentional attacks on complex networks. A lot of research is being done to devise centrality measures which could efficiently identify the most influential nodes in a network. There are two major approaches to this problem: On one hand, deterministic strategies that exploit knowledge about the overall network topology, while on the other end, random strategies are completely agnostic about the network structure. Centrality measures that can deal with a limited knowledge of the network structure are of prime importance. Indeed, in practice, information about the global structure of the overall network is rarely available or hard to acquire. Even if available, the structure of the network might be too large that it is too much computationally expensive to calculate global centrality measures. To that end, a centrality measure is proposed here that requires information only at the community level. Indeed, most of the real-world networks exhibit a community structure that can be exploited efficiently to discover the influential nodes. We performed a comparative evaluation of prominent global deterministic strategies together with stochastic strategies, an available and the proposed deterministic community-based strategy. Effectiveness of the proposed method is evaluated by performing experiments on synthetic and real-world networks with community structure in the case of immunization of nodes for epidemic control.

  13. Central Endoscopy Reading in Inflammatory Bowel Diseases.

    Science.gov (United States)

    Panés, Julián; Feagan, Brian G; Hussain, Fez; Levesque, Barrett G; Travis, Simon P

    2016-09-01

    Endoscopic assessment of the presence and severity of endoscopic lesions has become an essential part of clinical trials in ulcerative colitis and Crohn's disease, for both patient eligibility and outcome measures. Variability in lesion interpretation between and within observers and the potential bias of local investigators in patient assessment have long been recognized. This variability can be reduced, although not completely removed, by independent evaluation of the examinations by experienced off-site (central) readers, properly trained in regard to lesion definition and identification, that should be removed from direct patient contact and blinded to any other clinical or study data. Adding endoscopic demonstration of active disease to eligibility criteria has the potential to reduce placebo response rates, whereas in outcome assessment it has the potential to provide a more precise estimation of the treatment effect, increasing the efficiency of the study. Central endoscopy reading is still at the beginning of its development, and the paradigms of central reading need refinement in terms of the number of readers, the process by which a final score is assigned, the selection and sequence of central readers, and the endoscopic indices of choice. PMID:27604978

  14. Central Pontine and Extrapontine Myelinolysis in Encephalitis

    Directory of Open Access Journals (Sweden)

    Suvrendu Sankar Kar

    2013-08-01

    Full Text Available A 15 years male presented with fever, convulsion, unconsciousness and dystonia of acute onset. He was investigated and treated. MRI brain shows central pontine and extrapontine myelinolysis. Osmotic injury, Wilson's disease and other possibilities were excluded by clinical findings with supportive investigations. Patient was improved satisfactorily with treatment. [Natl J Med Res 2013; 3(4.000: 420-421

  15. Ichthyofauna of the reservoirs of Central Vietnam

    Directory of Open Access Journals (Sweden)

    I. A. Stolbunov

    2012-01-01

    Full Text Available Species composition, distribution and abundance of fish in the pelagic and littoral zone of four reservoirs of Central Vietnam (Suoi Chau, Kam Lam, Da Ban and Suoi Dau were studied first. According to the research data the fish community of the reservoirs is represented by 43 species of 19 fish families.

  16. Caupolicana in Central America (Hymenoptera, Colletidae, Diphaglossinae

    Directory of Open Access Journals (Sweden)

    Charles Michener

    2009-02-01

    Full Text Available Caupolicana (Zikanapis wileyi n. sp. from Guatemala is described. New locality records are noted for other species, and the hitherto unknown female of C. (Z. rozenorum Michener, Engel, and Ayala from Guatemala is described. A key for the identification of Central American Caupolicana is provided.

  17. Imaging of the fetal central nervous system

    NARCIS (Netherlands)

    Pistorius, L.R.

    2008-01-01

    Introduction : Ultrasound and MR imaging of the fetal central nervous system (CNS) develop at an ever-increasing rate. Theoretically, the two modalities should be synergistic, but a literature review revealed the difficulties of determining the merit of either technique and revealed gaps in our know

  18. On the dimension of twisted centralizer codes

    OpenAIRE

    Glasby, S. P.; Praeger, Cheryl E.; Alahmadi, Adel

    2016-01-01

    Given a field $F$, a scalar $\\lambda\\in F$ and a matrix $A\\in F^{n\\times n}$, the twisted centralizer code $C_F(A,\\lambda):=\\{B\\in F^{n\\times n}\\mid AB-\\lambda BA=0\\}$ is a linear code of length $n^2$. When $A$ is cyclic and $\\lambda\

  19. Stochastic modelling of central heating systems

    DEFF Research Database (Denmark)

    Hansen, Lars Henrik

    1997-01-01

    and the degree Erhvervsforsker (a special Danish degree, equivalent to ``Industrial Ph.D.''). The thesis is mainly concerned with experimental design and system identification for individual components in water based central heating systems. The main contribution to this field is on the nonlinear dynamic...

  20. Exercise, Stress Resistance, and Central Serotonergic Systems

    OpenAIRE

    Greenwood, Benjamin N.; Fleshner, Monika

    2011-01-01

    Voluntary exercise reduces the incidence of stress-related psychiatric disorders in humans and prevents serotonin-dependent behavioral consequences of stress in rodents. Evidence reviewed herein is consistent with the hypothesis that exercise increases stress resistance by producing neuroplasticity at multiple sites of the central serotonergic system, which all help to limit the behavioral impact of acute increases in serotonin during stressor exposure.

  1. Internationalisation in Central and Eastern Europe

    DEFF Research Database (Denmark)

    Marinov, Marin Alexandrov

    This is a unique volume among the existing variety of publications on foreign direct investment (FDI) in Central and Eastern Europe (CEE) because it focuses on the internationalization process taking place there. It addresses the rapid changes of the business climate in the region that have led t...

  2. Hypersensitivity Responses in the Central Nervous System

    DEFF Research Database (Denmark)

    Khorooshi, Reza; Asgari, Nasrin; Mørch, Marlene Thorsen;

    2015-01-01

    of pathology in neuromyelitis optica (NMO), a central nervous system (CNS) demyelinating disease where activated neutrophils infiltrate, unlike in MS. The most widely used model for MS, experimental autoimmune encephalomyelitis, is an autoantigen-immunized disease that can be transferred to naive animals...

  3. Notes on Central Asian dragonflies (Insecta: Odonata)

    NARCIS (Netherlands)

    Schoorl Jr., J.W.

    2000-01-01

    New and old material from Central Asia is published. In total 38 species are recorded from various locations in this region. For the more interesting species notes and figures are provided. One probably new Ischnura species is briefly described, but not formally named. For a, possibly new, subspecie

  4. THE LICHENS OF NORTH CENTRAL OKLAHOMA

    Directory of Open Access Journals (Sweden)

    DARVIN WENDELL KECK

    2006-12-01

    Full Text Available Over 1,000 specimens of lichens were collected at 78 collecting stations in 11 counties of North Central Oklahoma during 1959 and 1960. The objectives were to identify lichens collected in the area; to establish a record of lichen distribution for each county in the area; and to analyze the ecological relationships.

  5. Universities and Knowledge Production in Central Europe

    Science.gov (United States)

    Kwiek, Marek

    2012-01-01

    The article discusses an East/West divide in Europe in university knowledge production. It argues that the communist and post-communist legacies in the four major Central European economies studied (Poland, Hungary, the Czech Republic and the Slovak Republic) matter substantially for educational and research systems. The differences in university…

  6. Stone age transitions. Neolithisation in central Scandinavia

    Directory of Open Access Journals (Sweden)

    Helena Knutsson

    2003-01-01

    Full Text Available A summary of a series of individual research projects focused on the processes from the Mesolithic to the Late Neolithic in central Scandinavia. The projects were embeded in the "Coast to Coast project". The historicity in this process was emphasised.

  7. Best Minds Sought for Central Office, Startups

    Science.gov (United States)

    Maxwell, Lesli A.

    2009-01-01

    The central office isn't being overlooked in the movement to find and develop top talent for school districts. Although ways to recruit, groom, and keep top teachers and strong principals tend to dominate discussions of "human capital" needs in education, a handful of nonprofit organizations and foundations also see providing smart managers as…

  8. Central Limit Theorem for Coloured Hard Dimers

    Directory of Open Access Journals (Sweden)

    Maria Simonetta Bernabei

    2010-01-01

    Full Text Available We study the central limit theorem for a class of coloured graphs. This means that we investigate the limit behavior of certain random variables whose values are combinatorial parameters associated to these graphs. The techniques used at arriving this result comprise combinatorics, generating functions, and conditional expectations.

  9. Ablated tektite from the central Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Glass, B.P.; Chapman, D.R.; ShyamPrasad, M.

    A well-preserved ablated (button-shaped) tektite recovered from the surface sediments of the central Indian Ocean lacks flow ridges and has apparently undergone ablation of 6.9 to 7.9 mm. The lack of flow ridges and amount of ablation indicate that...

  10. Petrology of tectonically segmented Central Indian Ridge

    Digital Repository Service at National Institute of Oceanography (India)

    Mukhopadhyay, R.; Iyer, S.D.

    Distribution and mineralogy of various rock types along the 4200-km-long slow-spreading Central Indian Ridge, between Owen fracture zone in the north and Indian Ocean triple junction in the south, is studied in the light of ridge segmentation...

  11. Azole-Resistant Central Nervous System Aspergillosis

    NARCIS (Netherlands)

    J.W.M. van der Linden; R.R. Jansen; D. Bresters; C.E. Visser; S.E. Geerlings; E.J. Kuijper; W.J.G. Melchers; P.E. Verweij

    2009-01-01

    Three patients with central nervous system aspergillosis due to azole-resistant Aspergillus fumigatus (associated with a leucine substitution for histidine at codon 98 [L98H] and a 34-base pair repeat in tandem in the promoter region) are described. The patients were treated with combination therapy

  12. Azole-resistant central nervous system aspergillosis.

    NARCIS (Netherlands)

    Linden, J.W.M. van der; Jansen, R.R.; Bresters, D.; Visser, C.E.; Geerlings, S.E.; Kuijper, E.J.; Melchers, W.J.G.; Verweij, P.E.

    2009-01-01

    Three patients with central nervous system aspergillosis due to azole-resistant Aspergillus fumigatus (associated with a leucine substitution for histidine at codon 98 [L98H] and a 34-base pair repeat in tandem in the promoter region) are described. The patients were treated with combination therapy

  13. Larger foraminifera from Central Falcon (Venezuela)

    NARCIS (Netherlands)

    Gorter, Nettie E.; Vlerk, van der I.M.

    1931-01-01

    Dr. H. G. Kugler, chief geologist of the North Venezuelan Petroleum Company, at Puerto Cabello, entrusted us with the examination of a collection of larger foraminifera, selected from material collected by the geologists of this Company in Central Falcon. Dr. A. Senn kindly added material that had a

  14. Volkswagen Sets up Central Lab in BRICI

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ On June 2, Volkswagen Corp of Germany settled its Chinese central laboratory in Sinopec Beijing Research Institute of Chemical Industry (BRICI). This is the top-level lab of Volkswagen in Asia - Pacific region and it marks another close cooperation between Volkswagen Corp of Germany and Sinopec Corp.

  15. Notes on Central Asian dragonflies (Insecta: Odonata)

    OpenAIRE

    Schoorl Jr., J.W.

    2000-01-01

    New and old material from Central Asia is published. In total 38 species are recorded from various locations in this region. For the more interesting species notes and figures are provided. One probably new Ischnura species is briefly described, but not formally named. For a, possibly new, subspecies of Sympetrum sinaiticum Dumont, 1977, a short diagnosis with figures is provided.

  16. Enhancing the Capability of Central Finance Agencies

    OpenAIRE

    Allen, Richard; Grigoli, Francesco

    2012-01-01

    A well-organized and effective finance ministry and its associated central finance agencies (CFAs) are essential to good fiscal outcomes. Recent studies of CFAs in selected low-income countries demonstrate that their organizational structure varies widely and that decision making on public finance is strongly influenced by political economy factors. This note presents some common themes ar...

  17. Central Virginia Community College 1999 Fact Book.

    Science.gov (United States)

    Hicks, Geoffrey

    The Fact Book is an annual publication of the Office of Research, Assessment and Planning at Central Virginia Community College (CVCC). It includes data and trends from 1994-1998 and is divided into six parts: (1) "The College" includes information on the College Board, institutional history, facilities, mission and goals, revenues and…

  18. The ultimate determinants of central bank independence

    NARCIS (Netherlands)

    Eijffinger, S.C.W.; Schaling, E.

    1995-01-01

    Using a graphical method, a new way of determining the optimal degree of central bank conservativeness is developed in this paper. Unlike Lohmann (1992) and Rogoff (1985), we are able to express the upper and lower bounds of the interval containing the optimal degree of conservativeness in terms of

  19. Gabapentin inhibits central sensitization during migraine

    Institute of Scientific and Technical Information of China (English)

    Yanbo Zhang; Guo Shao; Wei Zhang; Sijie Li; Jingzhong Niu; Dongmei Hu; Mingfeng Yang; Xunming Ji

    2013-01-01

    Peripheral and central sensitizations are phenomena that occur during migraine. The role of pentin, a migraine preventive drug, on central sensitization remains unclear. In this study, a rat model of migraine was established by electrical stimulation of the trigeminal ganglion, and the an-imals were given intragastric gabapentin. Changes in amino acid content in the cerebrospinal fluid and protein kinase C membrane translocation in the spinal trigeminal nucleus were examined to clarify the mechanisms underlying the efficacy of gabapentin in the treatment of central sensitization during migraine. Electrophysiology, liquid chromatography-mass spectrometry and western blot analysis results revealed that gabapentin reduces neuronal excitability in the spinal nucleus in the trigeminal nerve, decreases excitatory amino acid content and inhibits the activation of protein ki-nase C. This provides evidence that excitatory amino acids and protein kinase C are involved in the formation and maintenance of central sensitization during migraine. Gabapentin inhibits migraine by reducing excitatory amino acid content in the cerebrospinal fluid and inhibiting protein kinase C ac-tivation.

  20. Central rotations of Milky Way Globular Clusters

    CERN Document Server

    Fabricius, Maximilian H; Rukdee, Surangkhana; Saglia, Roberto P; Bender, Ralf; Hopp, Ulrich; Thomas, Jens; Opitsch, Michael; Williams, Michael J

    2014-01-01

    Most Milky Way globular clusters (GCs) exhibit measurable flattening, even if on a very low level. Both cluster rotation and tidal fields are thought to cause this flattening. Nevertheless, rotation has only been confirmed in a handful of GCs, based mostly on individual radial velocities at large radii. We are conducting a survey of the central kinematics of Galactic GCs using the new Integral Field Unit instrument VIRUS-W. We detect rotation in all 11 GCs that we have observed so far, rendering it likely that a large majority of the Milky Way GCs rotate. We use published catalogs of the ACS survey of GCs to derive central ellipticities and position angles. We show that in all cases where the central ellipticity permits an accurate measurement of the position angle, those angles are in excellent agreement with the kinematic position angles that we derive from the VIRUS-W velocity fields. We find an unexpected tight correlation between central rotation and outer ellipticity, indicating that rotation drives fla...

  1. The Centrality of Engagement in Higher Education

    Science.gov (United States)

    Fitzgerald, Hiram E.; Bruns, Karen; Sonka, Steven T.; Furco, Andrew; Swanson, Louis

    2016-01-01

    The centrality of engagement is critical to the success of higher education in the future. Engagement is essential to most effectively achieving the overall purpose of the university, which is focused on the knowledge enterprise. Today's engagement is scholarly, is an aspect of learning and discovery, and enhances society and higher education.…

  2. Interferons in the central nervous system

    DEFF Research Database (Denmark)

    Owens, Trevor; Khorooshi, Reza M. H.; Wlodarczyk, Agnieszka;

    2014-01-01

    Interferons (IFNs) are implicated as an important component of the innate immune system influencing viral infections, inflammation, and immune surveillance. We review here the complex biological activity of IFNs in the central nervous system (CNS) and associated glial–immune interactions...

  3. Quantum Central Processing Unit and Quantum Algorithm

    Institute of Scientific and Technical Information of China (English)

    王安民

    2002-01-01

    Based on a scalable and universal quantum network, quantum central processing unit, proposed in our previous paper [Chin. Phys. Left. 18 (2001)166], the whole quantum network for the known quantum algorithms,including quantum Fourier transformation, Shor's algorithm and Grover's algorithm, is obtained in a unitied way.

  4. Fat graft myringoplasty in small central perforations

    Directory of Open Access Journals (Sweden)

    Chandni Sharma

    2014-01-01

    Full Text Available Background: Perforations of the tympanic membrane (TM are treated with various surgical techniques and materials. Although autologous temporalis fascia is the most common material used for the closure of TM perforations, however for a dry, small central perforation the fat graft myringoplasty (FM is a good alternative as it is a simple and cost-effective technique. Objectives: The aim of this study was to determine the efficacy of FM for repair of small central perforations. Suggestions for optimizing the outcome of FM are presented. Material and Methods: Twenty patients (10 males and 10 females who had uncomplicated dry small central perforation, which was confined to one quadrant of the pars tensa underwent FM. The outcome was evaluated after 1-week, 1-month, and 3 months. Results: After 3 months of follow-up, a closure rate of 80% was achieved. Mean preoperative air-bone (AB gap was 22.90 ± 6.54 dB and mean postoperative AB gap was 21.80 ± 6.28 dB. Mean improvement in AB gap postoperatively was 1.1 ± 2.63 dB. Conclusion: Fat graft myringoplasty, with its ease of technique and good graft uptake rate justifies its use in the closure of small dry central TM perforations.

  5. The Marstal Central Solar Heating Plant

    DEFF Research Database (Denmark)

    Heller, Alfred; Jochen, Dahm

    1999-01-01

    The central solar heating plant in Marstal is running since 1996 and has been monitored since. The resulting data from the plant is analysed and the plant performance evaluated. A TRNSYS-model (computersimulation) id prepared and validated based on the measured data from the plant. Acceptable good...

  6. Eye Movement Correlates of Acquired Central Dyslexia

    Science.gov (United States)

    Schattka, Kerstin I.; Radach, Ralph; Huber, Walter

    2010-01-01

    Based on recent progress in theory and measurement techniques, the analysis of eye movements has become one of the major methodological tools in experimental reading research. Our work uses this approach to advance the understanding of impaired information processing in acquired central dyslexia of stroke patients with aphasia. Up to now there has…

  7. Dust on UA1 central detector

    CERN Multimedia

    1982-01-01

    In March 1982 the central derector of UA1 was contaminated by dirt in the compressed air used for cooling during the bakeout of the beam pipe. The lengthy cleaning imposed a change of the collider schedule (Annual Report 1982 p. 114).

  8. Financial Stability and Central Bank Governance

    NARCIS (Netherlands)

    Koetter, Michael; Roszbach, Kasper; Spagnolo, Giancarlo

    2014-01-01

    The financial crisis has ignited a debate about the appropriate objectives and the governance structure of Central Banks. We use novel survey data to investigate the relation between these traits and banking system stability focusing in particular on their role in micro-prudential supervision. We fi

  9. The Mediterranean fruit fly in Central America

    International Nuclear Information System (INIS)

    Various methods of controlling the medfly are available and include the use of insecticides, bait sprays and the sterile insect technique (SIT). Each of these control strategies may be used alone or in sequence. With regard to the application of the SIT, the Joint FAO/IAEA Division of Atomic Energy in Food and Agriculture through its Insect and Pest Control Section and Entomology Laboratory is in an excellent position to assist in containing the medfly in Central America. For the past 12 years, the laboratory has participated in all phases of medfly control by sterile insect releases in various climates. This involvement has included planning of medfly campaigns, development of pre-release techniques (bait spraying, trapping, etc.) and shipment and release of sterilized medflies. Small-scale field tests utilizing the SIT have been carried out by nine countries: Italy (Procida, Capri), Spain, Cyprus, Israel, Tunisia, Peru, Panama, Costa Rica and Nicaragua. Other field projects presently being counselled and serviced are located in Argentina, Venezuela and the Canary Islands. The research and development that are still needed to effectively stabilize and gain control of the medfly situation in Central America include: The development and use of effective quarantine procedures in various countries; Development of effective conventional medfly control procedures under the conditions found in Central America; Development of methods to determine the geographic origin of medflies introduced into new areas; Medfly mass production (viz. all aspects of rearing Central American strains); Assessing the performance (competitiveness, etc.) of various strains; Logistics, including the development of systems for releasing pre-adult stages; Genetic rearing methods: developmental research in this area is particularly promising since the preferential production of males would allow considerable savings in the rearing costs of medflies for release; Development of adequate surveillance

  10. Clinical analysis and treatment of central pain due to headinjury

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    @@Central pain is induced by the involvement of the abnormal pain pathway due to diseases of the central nervous system. Central pain after brain trauma is common clinically, but it is often misdiagnosed and neglected because of lack of objective disturbances. We treated 20 cases of central pain after head injury by invigorating blood circulation and satisfactory result was obtained.

  11. Clinical significance of central corneal thickness and comparison of central corneal thickness

    Directory of Open Access Journals (Sweden)

    Özgür Çakıcı

    2014-03-01

    Full Text Available Significance of central corneal thickness has been increasing in ophthalmology practice. It is an important clinical evaluation tool especially prior to refractive surgery and in diagnosis of glaucoma and keratoconus. Refractive surgery is planned according to preoperative central corneal thickness measurements. Besides, in order to determine actual intraocular pressure, central corneal thickness is measured and corrected eye pressure is obtained. Today, devices used in measurement of central corneal thickness do the measurement according to two principles. First and relatively older method is ultrasonic method. Optic method is the second and more recent method. In daily practice, the most commonly used clinical method in measurement of central corneal thickness is ultrasound pachymeter. However, this measurement technique requires contact between cornea and probe and gives thinner measurement results compared to the methods that use optic principle. Recently, several technologic methods based on optics have been put in use; they provide advantages of non-contact technique and objective determination of central corneal thickness. Of these methods, most commonly used include Specular Microscopy, Optical coherence tomography, Laser Doppler Interferometry, Optical low coherence reflectometry pachymetry, Optic based topographic mapping (also called screening section pachymetry and Pentacam. In this article, it was aimed to evaluate importance of central corneal thickness in clinical use and compare measurement methods. J Clin Exp Invest 2014; 5 (1: 153-158

  12. Solitary Median Maxillary Central Incisor Versus Agenesis of the Maxillary Central Incisor.

    Science.gov (United States)

    de Carvalho, Fabrício Kitazono; Arid, Juliana; De Rossi, Andiara; Paula-Silva, Francisco W G; Nelson-Filho, Paulo

    2016-01-01

    A solitary median maxillary central incisor (SMMCI) is rare and affected individuals may carry a potentially serious condition known as SMMCI syndrome. However, many of these cases do not receive proper attention because they are misdiagnosed as agenesis of the maxillary central incisor. The purpose of this manuscript is to report two cases of children with only one maxillary central incisor and draw diagnostic differences between the entities. A correct diagnosis is very important because if an SMMCI is confirmed, the patient should be referred for genetic counseling. PMID:27098718

  13. Harada Group Uniquely Determined by Centralizer of a 2-Central Involution

    Institute of Scientific and Technical Information of China (English)

    M. Kratzer; G.O. Michler; M. Weller

    2003-01-01

    In this article we show that the sporadic simple Harada group G is uniquely determined up to isomorphism by the centralizer CG(z) of a 2-central involution z of G. This strengthens Y. Segev's uniqueness theorem [24] which required the known structure of the centralizers of two non-conjugate involutions.Using the second author's algorithm [19], we also provide a self-contained existence proof for the Harada group G by giving matrix generators inside GL133(19).Furthermore, the character table of G is determined and representatives for the conjugacy classes of the group are given as short words in the generating matrices.

  14. HANFORD SITE CENTRAL PLATEAU CLEANUP COMPLETION STRATEGY

    Energy Technology Data Exchange (ETDEWEB)

    BERGMAN TB

    2011-01-14

    Cleanup of the Hanford Site is a complex and challenging undertaking. The U.S. Department of Energy (DOE) has developed a comprehensive vision for completing Hanford's cleanup mission including transition to post-cleanup activities. This vision includes 3 principle components of cleanup: the {approx}200 square miles ofland adjacent to the Columbia River, known as the River Corridor; the 75 square miles of land in the center of the Hanford Site, where the majority of the reprocessing and waste management activities have occurred, known as the Central Plateau; and the stored reprocessing wastes in the Central Plateau, the Tank Wastes. Cleanup of the River Corridor is well underway and is progressing towards completion of most cleanup actions by 2015. Tank waste cleanup is progressing on a longer schedule due to the complexity of the mission, with construction of the largest nuclear construction project in the United States, the Waste Treatment Plant, over 50% complete. With the progress on the River Corridor and Tank Waste, it is time to place increased emphasis on moving forward with cleanup of the Central Plateau. Cleanup of the Hanford Site has been proceeding under a framework defmed in the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement). In early 2009, the DOE, the State of Washington Department of Ecology, and the U.S. Environmental Protection Agency signed an Agreement in Principle in which the parties recognized the need to develop a more comprehensive strategy for cleanup of the Central Plateau. DOE agreed to develop a Central Plateau Cleanup Completion Strategy as a starting point for discussions. This DOE Strategy was the basis for negotiations between the Parties, discussions with the State of Oregon, the Hanford Advisory Board, and other Stakeholder groups (including open public meetings), and consultation with the Tribal Nations. The change packages to incorporate the Central Plateau Cleanup Completion Strategy were

  15. THE ALLIANCE TRACHYNION DISTACHYAE RIVAS-MARTINEZ 1978 IN CENTRAL ITALYIN CENTRAL ITALY

    Directory of Open Access Journals (Sweden)

    M. DE SANCTIS

    2010-01-01

    Full Text Available The therophytic basiphilous vegetation of Central Italy has been generally framed in a single association Trifolio scabri- Hypochoeridetum achyrophori Biondi et al. 1997. We show that a considerable floristic variation exists inside Trifolio-Hypochoeridetum in Central Italy, and that it should be treated as a complex of no less than five different associations: Medicagini rigidulae-Trifolietum scabri Fanelli et al. hoc loco, Trifolio scabri-Hypochoeridetum achyrophori Biondi, Izco. Ballelli & Formica 1997 s.s, Hippocrepido siliquosae- Brachypodietum distachyi Fanelli et al. ad interim, Trigonello gladiatae-Brachypodietum distachyi Fanelli et al. hoc loc, Crucianello latifoliae-Hypochoeridetum achyrophori Filesi, Blasi, Di Marzio 1996. These associations are floristically and ecologically distinct, and show different geographical ranges in Central Italy. The great diversity of Trachynion distachyae in Central Italy is related to the widespread occurrence of limestone and calcareous alluvial rocks and to a climate with abundant winter and autumn rains very favourable to the development of winter annuals.

  16. Central Asia's raging waters the prospects of water conflict in Central Asia

    OpenAIRE

    Hartman, William B.

    2007-01-01

    This thesis examines the prospects of conflict caused by water scarcity in Central Asia. The thesis analyzes the three most recent political eras of Central Asia, Tsarist Russia, the Soviet Union and independence, utilizing indicators of water tensions including: water quality, water quantity, the management of water for multiple uses, the political divisions and geopolitical setting, state institutions and national water ethos. Although water is not likely to be the sole cause of a majo...

  17. Central nervous control of energy and glucose balance: focus on the central melanocortin system

    OpenAIRE

    Xu, Yong; Elmquist, Joel K.; Fukuda, Makoto

    2011-01-01

    Studies have suggested that manipulations of the central melanocortin circuitry by pharmacological agents produce robust effects on the regulation of body weight and glucose homeostasis. In this review, we discuss recent findings from genetic mouse models that have further established the physiological relevance of this circuitry in the context of glucose and energy balance. In addition, we will discuss distinct neuronal populations that respond to central melanocortins to regulate food intak...

  18. FINANCIAL CRISIS AND THE CENTRAL BANK SYSTEM

    Directory of Open Access Journals (Sweden)

    Richard POSPISIL

    2015-07-01

    Full Text Available The financial crisis that began in 2008 gradually developed into a global economic crisis and continues to this day. There is a lot of causes standing behind the creation, depth and process of the crisis, which is the deepest since the thirties of last centrury. One of the reasons can be found in the risky behavior of commercial banks, especially in the excessive lending of credits and mortgages. Its share on the financial crisis have central banks and their failure as the financial supervisory authority. But there is a lot of another causes of failures in the commercial banking system. And some of the causes lies outside the banking system and monetary policy. Its share of the blame has also become from state and its expenditure on the social policy.This article analyzes the role of the commercial banking system and the central banks on the financial crisis including prevention options and measures.

  19. Financial Crisis and the Central Bank System

    Directory of Open Access Journals (Sweden)

    RICHARD POSPISIL

    2015-05-01

    Full Text Available The financial crisis that began in 2008 gradually developed into a global economic crisis and continues to this day. There is a lot of causes standing behind the creation, depth and process of the crisis, which is the deepest since the thirties of last centrury. One of the reasons can be found in the risky behavior of commercial banks, especially in the excessive lending of credits and mortgages. Its share on the financial crisis have central banks and their failure as the financial supervisory authority. But there is a lot of another causes of failures in the commercial banking system. And some of the causes lies outside the banking system and monetary policy. Its share of the blame has also become from state and its expenditure on the social policy.This article analyzes the role of the commercial banking system and the central banks on the financial crisis including prevention options and measures.

  20. A Review of Select Centralized Pain Syndromes

    Directory of Open Access Journals (Sweden)

    David R. Spiegel

    2015-01-01

    Full Text Available Pain can be broadly divided into 3 classes, including nociceptive or inflammatory pain (protective, neuropathic (pathological, occurring after damage to the nervous system, or centralized (pathological, due to abnormal function but with no damage or inflammation to the nervous system. The latter has been posited to occur when descending analgesic pathways are attenuated and/or glutamatergic transmission is facilitated. Additionally, this “pain prone phenotype” can be associated with early life trauma and a suboptimal response to opiates. This article will review the relationships between centralized pain syndromes (ie, fibromyalgia, chronic low back pain, childhood sexual abuse, and opiate misuse. Finally, treatment implications, potentially effecting primary care physicians, will be discussed.

  1. Diagnosis and treatment of central diabetes insipidus

    Directory of Open Access Journals (Sweden)

    Ekaterina Aleksandrovna Pigarova

    2014-11-01

    Full Text Available Diabetes insipidus represents a serious disease that dramatically interferes with the everyday life of patients due to the need to constantly replenish of fluid lost in the urine, which comes amid shortage of synthesis, secretion or action of pituitary hormone vasopressin. The main difficulty is the differential diagnosis of types of diabetes insipidus in patients with the syndrome of polydipsia-polyuria as the correct differential diagnosis of these forms predetermine the safety and efficacy of further treatment. This lecture presents the current concepts of etiology, diagnosis and treatment of central diabetes insipidus (CDI. We give the comparative characteristics of various preparations of desmopressin for the treatment of the central form of the disease. We also consider the features of the management of selected patient populations with CDI: during pregnancy and lactation, pathology of the thirst sensation, after traumatic brain injury and neurosurgery.

  2. Hitherto unreported Agaricus species of Central India

    Directory of Open Access Journals (Sweden)

    MAHENDRA KUMAR RAI

    2010-11-01

    Full Text Available Karwa A, Rai MK. 2010. Hitherto unreported Agaricus species of Central India. Nusantara Bioscience 2: 141-145. Melghat forest region from Central India was surveyed for occurrence of medicinal and culinary mushrooms during the years 2005-2008. Out of total 153 species, ten species of Agaricus were recorded from different localities. Of these, seven species namely Agaricus bitorquis, A. subrufescens, A. augustus, A. placomyces, A. essettei, A. basioanolosus and Agaricus sp. nov (a new species are being reported for the first time from the region. The commercial button mushroom Agaricus bisporus lacks good breeding characters due to its bisporic nature. These wild cousins of the button mushroom can definitely prove to be a good source of genetic manipulations to the existing strains and also to develop new strains with improved characters.

  3. Central auditory neurons have composite receptive fields.

    Science.gov (United States)

    Kozlov, Andrei S; Gentner, Timothy Q

    2016-02-01

    High-level neurons processing complex, behaviorally relevant signals are sensitive to conjunctions of features. Characterizing the receptive fields of such neurons is difficult with standard statistical tools, however, and the principles governing their organization remain poorly understood. Here, we demonstrate multiple distinct receptive-field features in individual high-level auditory neurons in a songbird, European starling, in response to natural vocal signals (songs). We then show that receptive fields with similar characteristics can be reproduced by an unsupervised neural network trained to represent starling songs with a single learning rule that enforces sparseness and divisive normalization. We conclude that central auditory neurons have composite receptive fields that can arise through a combination of sparseness and normalization in neural circuits. Our results, along with descriptions of random, discontinuous receptive fields in the central olfactory neurons in mammals and insects, suggest general principles of neural computation across sensory systems and animal classes. PMID:26787894

  4. Hydropower development in the Central Himalayas

    Energy Technology Data Exchange (ETDEWEB)

    Singh, N. (Irrigation Design Organization, Rourkee (India))

    1992-10-01

    The Central Himalayas comprise eight hill districts of the State of Uttar Pradesh, India. These mountains are the source of the Ganga and its main tributaries: the Yamuna, Ramganga and Sarda rivers. The identified hydro potential of the Ganga, Yamuna, Sarda and their tributaries in the Central Himalayas is about 30 000 MW, with an annual average energy potential of 100 TWh. The projects which have been completed so far have only developed 3.2 per cent of this potential. The projects which are now under construction will exploit another 10.4 per cent of the potential. Thus, the untapped potential is as much as 85 per cent of the total. The minor tributaries also offer vast potential for mini and micro hydroelectric stations. In most conservative estimates, this potential is about 2000 MW. (author).

  5. [Central nervous system tumors in pregnancy].

    Science.gov (United States)

    Podciechowski, Lech; Nowakowska, Dorota; Bielak, Adam; Nowosławska, Emilia; Szymański, Wojciech; Polis, Lech; Krasomski, Grzechorz; Fiks, Tomasz; Wilczyński, Jan

    2003-12-01

    Central nervous system tumour in pregnancy constitutes a serious complication. Considering frequent difficulties in diagnostics and therapy, the aim of the study was to present our experience in management with pregnant women with brain and spinal cord tumours. Between 1988-2000, in The Research Institute Polish Mother's Memorial Hospital in Lodzi, 4 pregnant women had been diagnosed with brain and spinal cord tumours. The incidence of tumours complicating pregnancy was 1/11460. Two patients diagnosed at 29 weeks' gestation, underwent craniotomy and tumour resection during pregnancy. Two other women with central nervous system tumours diagnosed at 39 weeks' gestation, were operated in the postpartum period. The analysis of the postoperative period, gestation and/or postpartum period in all women and well-being of their new-borns confirm undertaken medical decisions. PMID:15029742

  6. Spherical explosion with central energy source

    CERN Document Server

    Masuyama, Miyu; Tsuboki, Yoichiro

    2015-01-01

    We present a novel semi-analytic solution describing the propagation of a spherical blast wave driven by a central energy source. The initial density profile has a power-law function of the distance from the center and the energy is injected only into the central region at a rate given by a power-law function of time. This solution is composed of three regions separated by the contact surface and the shock front. The innermost region is assumed to be uniform and the outside of the contact surface includes the shocked matter described by self-similar solutions. We analytically derive the applicable range of parameters of this solution from requirements to satisfy boundary conditions. We perform numerical simulations for flows with various values of parameters, some of which reside out of the thus derived applicable range, and compare with the semi-analytic solutions.

  7. Spherical explosion with a central energy source

    Science.gov (United States)

    Masuyama, Miyu; Shigeyama, Toshikazu; Tsuboki, Yoichiro

    2016-04-01

    We present a novel semi-analytic solution that describes the propagation of a spherical blast wave driven by a central energy source. The initial density profile has a power-law function of the distance from the center and the energy is injected only into the central region at a rate given by a power-law function of time. This solution is composed of three regions separated by the contact surface and the shock front. The innermost region is assumed to be uniform and the outside of the contact surface includes the shocked matter described by self-similar solutions. We analytically derive the applicable range of parameters of this solution from requirements needed to satisfy the boundary conditions. We perform numerical simulations for flows with various values of parameters, some of which reside out of the thus-derived applicable range, and compare the results with the semi-analytic solutions.

  8. A study of Central Exclusive Production

    Energy Technology Data Exchange (ETDEWEB)

    Monk, James; /Manchester U.

    2008-09-01

    Central exclusive production of a system X in a collision between two hadrons h is defined as hh {yields} h + X + h with no other activity apart from the decay products of X. This thesis presents predictions for the production cross section of a CP violating supersymmetric Higgs boson and the radion of the Randall-Sundrum model. The ExHuME Monte Carlo generator was written to simulate central exclusive processes and is described and explored. A comparison to di-jet observations made by the D0 detector at the Tevatron, Fermilab between January and June 2004 is made and the distributions found support the predictions of ExHuME.

  9. Centralizers in simple locally finite groups

    Directory of Open Access Journals (Sweden)

    Mahmut Kuzucuoğlu

    2013-03-01

    Full Text Available This is a survey article on centralizers of finitesubgroups in locally finite, simple groups or LFS-groups as wewill call them. We mention some of the open problems aboutcentralizers of subgroups in LFS-groups and applications of theknown information about the centralizers of subgroups to thestructure of the locally finite group. We also prove thefollowing: Let $G$ be a countably infinite non-linear LFS-groupwith a Kegel sequence $mathcal{K}={(G_i,N_i | iinmathbf{N} }$. If there exists an upper bound for ${ |N_i| |iin mathbf{N} }$, then for any finite semisimplesubgroup $F$ in $G$ the subgroup $C_G(F$ has elements oforder $p_i$ for infinitely many distinct prime $p_i$. Inparticular $C_G(F$ is an infinite group. This answers Hartley'squestion provided that there exists a bound on ${ |N_i| | iin mathbf{N}$.

  10. Infections associated with the central venous catheters.

    Science.gov (United States)

    Drasković, Biljana; Fabri, Izabella; Benka, Anna Uram; Rakić, Goran

    2014-01-01

    Central venous catheters are of an essential importance to critically ill patients who require long-term venous access for various purposes. Their use made the treatment much easier, but still they are not harmless and are prone to numerous complications. Catheter infections represent the most significant complication in their use. The frequency of infections varies in different patient care settings, but their appearance mostly depends on the patient's health condition, catheter insertion time, localization of the catheter and type of the used catheter. Since they are one of the leading causes of nosocomial infections and related to significant number of morbidity and mortality in intensive care units, it is very important that maximal aseptic precautions are taken during the insertion and the maintenance period. Prevention of infection of the central venous catheters demands several measures that should be applied routinely.

  11. Expansion of museums in Central Europe?

    Directory of Open Access Journals (Sweden)

    Jagodzińska, Katarzyna

    2015-06-01

    Full Text Available The paper presents reflections on the specificity of collections and museums of contemporary art in Central Europe and considers a possibility of creating a regional alternative for the West. The analysis is conducted in the context of the expansionist policy of contemporary museums – notably the Louvre, the Guggenheim Foundation, and the Hermitage – whose numerous new development projects gave rise to a number of dilemmas in the museological world. The author discusses global "museum brands" that invest in Central Europe and addresses the possible profits of the expansion of such "concerns" for culture in the region, as well as emphasises the potential of the region itself, which may be used for its development without the avail of the internationally renowned collectors' names.

  12. Iowa Central Quality Fuel Testing Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Heach, Don; Bidieman, Julaine

    2013-09-30

    The objective of this project is to finalize the creation of an independent quality fuel testing laboratory on the campus of Iowa Central Community College in Fort Dodge, Iowa that shall provide the exploding biofuels industry a timely and cost-effective centrally located laboratory to complete all state and federal fuel and related tests that are required. The recipient shall work with various state regulatory agencies, biofuel companies and state and national industry associations to ensure that training and testing needs of their members and American consumers are met. The recipient shall work with the Iowa Department of Ag and Land Stewardship on the development of an Iowa Biofuel Quality Standard along with the Development of a standard that can be used throughout industry.

  13. Sensitivity Analysis of Centralized Dynamic Cell Selection

    DEFF Research Database (Denmark)

    Lopez, Victor Fernandez; Alvarez, Beatriz Soret; Pedersen, Klaus I.;

    2016-01-01

    and a suboptimal optimization algorithm that nearly achieves the performance of the optimal Hungarian assignment. Moreover, an exhaustive sensitivity analysis with different network and traffic configurations is carried out in order to understand what conditions are more appropriate for the use of the proposed...... with two different traffic models, and it is not necessary to be able to connect to a large number of cells in order to reap most of the benefits of the centralized dynamic cell selection.......Centralized architectures with fronthauls can be used to deal with some of the problems inherently associated with dense small cell deployments. This study examines a joint cell assignment and scheduling solution for the downlink to increase the users’ data rates, based on cell switching...

  14. [Central nervous system malformations: neurosurgery correlates].

    Science.gov (United States)

    Jiménez-León, Juan C; Betancourt-Fursow, Yaline M; Jiménez-Betancourt, Cristina S

    2013-09-01

    Congenital malformations of the central nervous system are related to alterations in neural tube formation, including most of the neurosurgical management entities, dysraphism and craniosynostosis; alterations of neuronal proliferation; megalencefaly and microcephaly; abnormal neuronal migration, lissencephaly, pachygyria, schizencephaly, agenesis of the corpus callosum, heterotopia and cortical dysplasia, spinal malformations and spinal dysraphism. We expose the classification of different central nervous system malformations that can be corrected by surgery in the shortest possible time and involving genesis mechanisms of these injuries getting better studied from neurogenic and neuroembryological fields, this involves connecting innovative knowledge areas where alteration mechanisms in dorsal induction (neural tube) and ventral induction (telencephalization) with the current way of correction, as well as the anomalies of cell proliferation and differentiation of neuronal migration and finally the complex malformations affecting the posterior fossa and current possibilities of correcting them.

  15. Centralized, Decentralized, and Hybrid Purchasing Organizations

    DEFF Research Database (Denmark)

    Bals, Lydia; Turkulainen, Virpi

    This paper addresses one of the focal issues in purchasing and supply management – global sourcing – from an organizational design perspective. In particular, we elaborate the traditional classification of global sourcing organization designs into centralized, decentralized, and hybrid models. We...... illustrate with our empirical analysis on global sourcing organization design at Global Chemical Company (GCC, a pseudonym) that revisiting the conventional wisdom about global sourcing organization designs is required; by engaging in a detailed, subfirm level of analysis on the design of the purchasing...... organization we can identify organization designs beyond the classical centralization-decentralization continuum. We also provide explanations for the observed organization design at GCC. The study contributes to research on purchasing and supply management as well as research on organization design....

  16. Second-generation central receiver technology comparison

    Science.gov (United States)

    Klimas, P. C.; Becker, M.

    Fifteen years of solar thermal technology development have produced a considerable amount of knowledge relating to the production of electricity from central receiver power plants. This body of knowledge is under examination by researchers from the United States and the Federal Republic of Germany for the purpose of defining the next generation central receiver electricity producers. This second generation power plant is expected to represent a significant step towards commercialization of these systems. During the course of the study, specific activities needed to realize this next-step technology are being defined. The study is an international team effort. Under the International Energy Agency Small Solar Power Systems project, researchers from DLR, Interatom, Sandia National Laboratories, and Bechtel have designed a study in which technologies relating to existing systems are quantified, logical next-step systems are characterized, and future potential advances are identified. The receiver concepts under investigation are: salt-in-tube, volumetric, and direct absorption. Two plant performance levels are examined, 30 and 100 MW(sub e). Each concept is applied with common capacity factors, solar multiples, and types and sizes of heliostats at each performance level. Availability and uncertainty analyses are also performed. Annual energy production figures are calculated using the SOLERGY computer code. Capital and Operation and Maintenance cost methodologies are mutually agreed upon in order that levelized energy cost calculations will be consistent for each power plant. During the course of this effort, further potential advances in central receiver technology have continued to become apparent. These possible areas for improvement will be described. An additional comparison is being made between central receivers and trough-based systems.

  17. Virasoro central charges for Nichols algebras

    CERN Document Server

    Semikhatov, A M

    2011-01-01

    Virasoro central charge associated with Nichols algebras is invariant under the Weyl groupoid action and takes very suggestive values for some items in Heckenberger's list of rank-2 Nichols algebras. In particular, this might be taken as an indication of the existence of reasonable logarithmic extensions of W3==WA2, WB2, and WG2 models of conformal field theory. In the W3 case, the construction of an octuplet extended algebra is outlined.

  18. Ethnobotanical remarks on Central and Southern Italy

    OpenAIRE

    Lucia Leporatti; Guarrera Paolo

    2007-01-01

    Abstract Background The present paper is a brief survey on the ethnobotanical works published by the Authors since 1981, concerning the research carried out in some southern and central Italian regions. Before Roman domination these territories were first inhabited by local people, while the southern areas were colonized by the Greeks. These different cultural contributions left certain traces, both in the toponyms and in the vernacular names of the plants and, more generally, in the culture ...

  19. CDF Central Preshower and Crack Detector Upgrade

    OpenAIRE

    Artikov, A.

    2007-01-01

    The CDF Central Preshower and Crack Detector Upgrade consist of scintillator tiles with embedded wavelength-shifting fibers, clear-fiber optical cables, and multi-anode photomultiplier readout. A description of the detector design, test results from R&D studies, and construction phase are reported. The upgrade was installed late in 2004, and a large amount of proton-antiproton collider data has been collected since then. Detector studies using those data are also discussed.

  20. The central part of CMS is lowered

    CERN Multimedia

    Maximilien Brice

    2007-01-01

    On 28 February 2007, the CMS central piece containing the magnet and weighing as much as five Jumbo jets (1920 tonnes) was gently lowered into place. Only 20 cm separated the detector, which was suspended by four huge cables, each with 55 strands and sophisticated monitoring to minimize sway and tilt, from the walls of the shaft. The entire process took about 10 hours to complete.

  1. A Central Limit Theorem for Punctuated Equilibrium

    OpenAIRE

    Bartoszek, Krzysztof

    2016-01-01

    Current evolutionary biology models usually assume that a phenotype undergoes gradual change. This is in stark contrast to biological intuition, which indicates that change can also be punctuated - the phenotype can jump. Such a jump can especially occur at speciation, i.e. dramatic change occurs that drives the species apart. Here we derive a central limit theorem for punctuated equilibrium. We show that, if adaptation is fast, for weak convergence to hold, dramatic change has to be a rare e...

  2. Gas industry in Central and Eastern Europe

    Energy Technology Data Exchange (ETDEWEB)

    Razavi, H. [World Bank, Washington, DC (United States)

    1997-09-01

    The transition to a market economy in Central and Eastern Europe (CEE) has had many implications for the gas sector, in particular on the market development and prices, on the structure of the sector and on the investment level. The institutional and financial barriers to the development of CEE`s gas markets are summarized. Technical and marketing barriers are discussed, covering system design and integrity, metering, markets and energy efficiency. Finally, World Bank role and objectives are outlined. (R.P.)

  3. Tectonomagmatic Associations on the Central Andean Plateau

    Science.gov (United States)

    de Silva, S. L.; Viramonte, J. G.

    2012-12-01

    The Neogene evolution of the Central Andes is characterized by a strong association between plate convergence, mountain building and plateau formation, and magmatism. Plateau uplift by crustal shortening and thickening in the lower crust is broadly coincident with large scale silicic magmatism defined by the Neogene Central Andean ignimbrite province. Of particular interest here are the spatiotemporal correlations between silicic magmatism and tectonic evolution of the Altiplano-Puna plateau. Although magmatism is driven by the subduction-related flux from mantle to crust, the shift to "crustal" magmatism as indicated by elevated crustal isotopic indices after ~10Ma suggests a link between crustal thickening, plateau formation and silicic magmatism. In particular, elevated geotherms associated with crustal thickening and enhanced mantle flux associated with lithospheric delamination may have played a role in thermally preparing the Central Andean crust for enhanced silicic magma production during the extensive Neogene ignimbrite flare-up. Emplacement of these magmas in the upper crust throughout the Neogene may have fuelled a period of significant interaction between magmatism and tectonism on the plateau. With particular reference to the 21° to 24°S segment of the Central Andes, spatial and structural coincidence of calderas of the Altiplano Puna Volcanic Complex with the NW-SE striking Calama-Olacapata-El Toro fault zone suggests significant tectonomagmatic interaction. Location of calderas suggest that these regional faults focused magma intrusion and storage, while spatially and temporally correlated eruption pulses connote a tectonic control. Indeed, current thermomechanical models of magma chamber development and eruption triggering promote a role for external triggering of "perched" upper crustal magma chambers. This might have been achieved by melt-enhanced deformation, or alternatively, significant uplift (~1km) associated with the development of large

  4. RETAIL SUPPLY CHAIN MANAGEMENT THROUGH CENTRALIZED DISTRIBUTION

    OpenAIRE

    Davor Dujak

    2012-01-01

    The paper reviews the trends in the design of distribution systems in retail supply chain management. Through goals, design decisions and costs of distribution system or distribution network, the paper points to the complexity and importance of this area of supply chain management. The goal of paper is to present modern trends in the distribution system, as well as specify the advantages and disadvantages of the leading distribution systems, with a special emphasis on the central distribution...

  5. Strategy as Central and Peripheral Processes

    OpenAIRE

    Juul Andersen, Torben; Fredens, Kjeld

    2012-01-01

    Corporate entrepreneurship is deemed essential to uncover opportunities that shape the future strategic path and adapt the firm to environmental change (e.g., Covin and Miles, 1999; Wolcott and Lippitz, 2007). At the same time, rational central processes are important to execute strategic actions in a coordinated manner (e.g., Baum and Wally, 2003; Brews and Hunt, 1999; Goll and Rasheed, 1997). That is, the organization’s adaptive responses and dynamic capabilities are embedded...

  6. Human Rights Training for Central Government Officials

    Institute of Scientific and Technical Information of China (English)

    OUR STAFF REPORTER

    2007-01-01

    @@ More than 50 officials from central government departments attended a human rights training class held in Nanchang,Jiangxi Province, on May 29-June 2. The class was sponsored by the State Council Information Office, during which the trainees attended lectures given on China's human rights concepts and the current human rights conditions in the country,human rights theories and international human rights instruments and protection of human rights under the rule of law.

  7. Sensitivity Analysis of Centralized Dynamic Cell Selection

    DEFF Research Database (Denmark)

    Lopez, Victor Fernandez; Alvarez, Beatriz Soret; Pedersen, Klaus I.;

    2016-01-01

    and a suboptimal optimization algorithm that nearly achieves the performance of the optimal Hungarian assignment. Moreover, an exhaustive sensitivity analysis with different network and traffic configurations is carried out in order to understand what conditions are more appropriate for the use of the proposed...... with two different traffic models, and it is not necessary to be able to connect to a large number of cells in order to reap most of the benefits of the centralized dynamic cell selection....

  8. INTERNATIONAL TERRORISM AND CENTRAL ASIA: PREMATURE ASSESSMENTS

    OpenAIRE

    Sabol, Steven

    2008-01-01

    In the months leading up to, and the first few years after, the Soviet Union collapsed numerous articles and books were published that claimed Islamic "fundamentalism" was likely to emerge in Central Asia. These fears were predicated on numerous scenarios, the most important being the ongoing political and military crisis in Afghanistan and Iranian attempts to increase its influence in the region. I will argue, however, that these concerns were premature and that the real threat to the stabil...

  9. CENTRAL ASIA IN SEARCH OF STABILITY

    OpenAIRE

    Plastun, Vladimir

    2008-01-01

    The tension in the Central Asian Region, particularly in its southern part, which includes Afghanistan, Pakistan, and Iran, largely affects the rest of this vast area and forces the United States and its allies to seek prompt settlement of the crisis they have on their hands. The situation in occupied Iraq is tense; the Turkish invasion into Iraqi Kurdistan in search of terrorists of the Kurdistan Workers’ Party did nothing to relieve the tension; the conflict area spread even further. Two ot...

  10. Central sleep apnoea—a clinical review

    OpenAIRE

    Muza, Rexford T.

    2015-01-01

    Central sleep apnoea (CSA) is characterised by recurrent apnoeas during sleep with no associated respiratory effort. It mostly results from withdrawal of the wakefulness drive in sleep leaving ventilation under metabolic control. A detailed physiological understanding of the control of breathing in wakefulness and sleep is essential to the understanding of CSA. It encompasses a diverse group of conditions with differing aetiologies and pathophysiology. Likewise treatment varies according to u...

  11. The Journal Rankings of Central Banks

    OpenAIRE

    Kohlscheen, Emanuel

    2011-01-01

    This paper analyzes the citation patterns of the central banks of the 15 largest monetary areas of the world that had an active working paper series in 2010. It proceeds to construct a novel journal ranking that is more suited for monetary authorities than the academic journal rankings currently in vogue. We report individual country rankings as well as the global rankings. While important regional differences emerge, the Journal of Monetary Economics, the American Economic Review, the Journa...

  12. Time perception mechanisms at central nervous system

    OpenAIRE

    Rhailana Fontes; Jéssica Ribeiro; Gupta, Daya S.; Dionis Machado; Fernando Lopes-Júnior; Francisco Magalhães; Victor Hugo Bastos; Kaline Rocha; Victor Marinho; Gildário Lima; Bruna Velasques; Pedro Ribeiro; Marco Orsini; Bruno Pessoa; Marco Antonio Araujo Leite

    2016-01-01

    The five senses have specific ways to receive environmental information and lead to central nervous system. The perception of time is the sum of stimuli associated with cognitive processes and environmental changes. Thus, the perception of time requires a complex neural mechanism and may be changed by emotional state, level of attention, memory and diseases. Despite this knowledge, the neural mechanisms of time perception are not yet fully understood. The objective is to relate the mechanisms...

  13. Geochemical drainage survey of central Argyll, Scotland

    OpenAIRE

    Coats, J.S.; Tandy, B.C.; Michie, U.McL

    1982-01-01

    A reconnaissance geochemical drainage survey of 720 km2 of Dalradian outcrop in central Argyll identified base-metal anomalies in the Pyrite Zone, Ardrishaig Phyllites, Loch Tay Limestone and the Green Beds. Faulting and igneous intrusion modified the distribution of metal content within these formations. In the results of the reconnaissance survey, copper reached maxima of 170 ppm and 1454 ppm in stream sediments and panned concentrates respectively; lead 1050 ppm ...

  14. Central Serous Chorioretinopathy Mistaken for Tuberculous Choroiditis

    OpenAIRE

    Marina Papadia; Herbort, Carl P.

    2011-01-01

    Purpose: To report a patient erroneously diagnosed with tuberculous choroiditis who was accordingly treated with long term steroids which in turn, worsened the actual disease process that turned out to be central serous chorioretinopathy (CSC). Case Report: A 59-year-old Caucasian man developed a chorioretinal disease in his right eye in 1997. Having a positive tuberculin skin test, tuberculous chorioretinitis was suspected and antituberculous therapy was administered for 4 months. In 200...

  15. The emergence of echinococcosis in central Asia

    OpenAIRE

    Torgerson, P.R.

    2013-01-01

    Following the collapse of the Soviet Union in 1991, there was an increase in the number of cases of human echinococcosis recorded throughout central Asia. Between 1991 and 2001 incidence rates of cystic echinococcosis (CE) increased by 4 fold or more. There also appeared to be increases in prevalence of CE in livestock and prevalences of Echinococcus granulosus reported in dogs. The increase in human echinococcosis was associated with changes in livestock husbandry, decline in veterinary publ...

  16. Lagrange, central norms, and quadratic Diophantine equations

    OpenAIRE

    R. A. Mollin

    2005-01-01

    We consider the Diophantine equation of the form x2−Dy2=c, where c=±1,±2, and provide a generalization of results of Lagrange with elementary proofs using only basic properties of simple continued fractions. As a consequence, we achieve a completely general, simple, and elegant criterion for the central norm to be 2 in the simple continued fraction expansion of D.

  17. Lagrange, central norms, and quadratic Diophantine equations

    Directory of Open Access Journals (Sweden)

    R. A. Mollin

    2005-01-01

    Full Text Available We consider the Diophantine equation of the form x2−Dy2=c, where c=±1,±2, and provide a generalization of results of Lagrange with elementary proofs using only basic properties of simple continued fractions. As a consequence, we achieve a completely general, simple, and elegant criterion for the central norm to be 2 in the simple continued fraction expansion of D.

  18. Highly-anisotropic hydrodynamics for central collisions

    CERN Document Server

    Ryblewski, Radoslaw

    2016-01-01

    The framework of leading-order anisotropic hydrodynamics is supplemented with realistic equation of state and self-consistent freeze-out prescription. The model is applied to central proton-nucleus collisions. The results are compared to those obtained within standard Israel-Stewart second-order viscous hydrodynamics. It is shown that the resulting hadron spectra are highly-sensitive to the hydrodynamic approach that has been used.

  19. Pandillas and Security in Central America

    OpenAIRE

    Thomas C. Bruneau

    2014-01-01

    This article introduces the topic of pandillas (street gangs) and their implications for security in Central America. There is minimal scholarly literature on pandillas and security. In part this is due to serious challenges in analyzing pandillas. First, pandilla members consider truth to be situational; data derived directly from them is suspect. Second, those who know most about them are involved in NGOs that rely on foreign assistance for their work. The project reports the...

  20. Urban Governance and Participation in Central Mexico

    OpenAIRE

    Valeria Guarneros-Meza

    2007-01-01

    Valeria Guarneros-Meza looks at national aspects that characterize Mexico's democratization and decentralization processes, and their impact upon the central region of Mexico. Based on the region's social characteristics, she discusses the concept of ‘urban governance’ in terms of its ambiguity, which promotes municipal systems of participation at the same time as it fragments their internal organization. Development (2007) 50, 104–109. doi:10.1057/palgrave.development.1100340

  1. Central bank learning and monetary policy

    OpenAIRE

    Mewael F. Tesfaselassie

    2008-01-01

    We analyze optimal monetary policy when a central bank has to learn about an unknown coefficient that determines the effect of surprise inflation on aggregate demand. We derive the optimal policy under active learning and compare it to two limiting cases---certainty equivalence policy and cautionary policy, in which learning takes place passively. Our novel result is that the two passive learning policies represent an upper and lower bound for the active learning policy, irrespective of the s...

  2. Probabilistic seismic hazard assessment for Central Asia

    Directory of Open Access Journals (Sweden)

    Shahid Ullah

    2015-04-01

    Full Text Available Central Asia is one of the seismically most active regions in the world. Its complex seismicity due to the collision of the Eurasian and Indian plates has resulted in some of the world’s largest intra-plate events over history. The region is dominated by reverse faulting over strike slip and normal faulting events. The GSHAP project (1999, aiming at a hazard assessment on a global scale, indicated that the region of Central Asia is characterized by peak ground accelerations for 10% probability of exceedance in 50 years as high as 9 m/s2. In this study, carried out within the framework of the EMCA project (Earthquake Model Central Asia, the area source model and different kernel approaches are used for a probabilistic seismic hazard assessment (PSHA for Central Asia. The seismic hazard is assessed considering shallow (depth < 50 km seismicity only and employs an updated (with respect to previous projects earthquake catalog for the region. The seismic hazard is calculated in terms of macroseismic intensity (MSK-64, intended to be used for the seismic risk maps of the region. The hazard maps, shown in terms of 10% probability of exceedance in 50 years, are derived by using the OpenQuake software [Pagani et al. 2014], which is an open source software tool developed by the GEM (Global Earthquake Model foundation. The maximum hazard observed in the region reaches an intensity of around 8 in southern Tien Shan for 475 years mean return period. The maximum hazard estimated for some of the cities in the region, Bishkek, Dushanbe, Tashkent and Almaty, is between 7 and 8 (7-8, 8.0, 7.0 and 8.0 macroseismic Intensity, respectively, for 475 years mean return period, using different approaches. The results of different methods for assessing the level of seismic hazard are compared and their underlying methodologies are discussed.

  3. Two root canals in maxillary central incisor

    Directory of Open Access Journals (Sweden)

    Fábio de Almeida Gomes

    2011-07-01

    Full Text Available Introduction and objective: The success of endodontic treatment requires the knowledge of tooth morphology and its variations. Case report: This clinical article reports an unusual root canal configuration that was detected in a maxillary central incisor with two root canals, demonstrated by radiographic and computerized tomography exams. Conclusion: Knowledge of endodontic anatomy as well as the obtainment of both preoperative radiographs and tomography is important to detect abnormal tooth morphology.

  4. Nucleotide Manipulatives to Illustrate the Central Dogma

    Directory of Open Access Journals (Sweden)

    Sonja B. Yung

    2015-08-01

    Full Text Available The central dogma is a core concept that is critical for introductory biology and microbiology students to master. However, students often struggle to conceptualize the processes involved, and fail to move beyond simply memorizing the basic facts. To encourage critical thinking, we have designed a set of magnetic nucleotide manipulatives that allow students to model DNA structure, along with the processes of replication, transcription, and translation.

  5. Nucleotide Manipulatives to Illustrate the Central Dogma†

    OpenAIRE

    Sonja B. Yung; Todd P. Primm

    2015-01-01

    The central dogma is a core concept that is critical for introductory biology and microbiology students to master. However, students often struggle to conceptualize the processes involved, and fail to move beyond simply memorizing the basic facts. To encourage critical thinking, we have designed a set of magnetic nucleotide manipulatives that allow students to model DNA structure, along with the processes of replication, transcription, and translation.

  6. WHITHER "HEARTLAND"? CENTRAL ASIA, GEOGRAPHY AND GLOBALIZATION

    OpenAIRE

    Hekimoglu, Levent

    2005-01-01

    This article attempts a double task. First, it looks at the main premises of Halford J. Mackinder's analysis in his renowned 1904 address to the Royal Geographical Society, The Geographical Pivot of History, and discusses some of the problems. It observes that these problems have actually rendered the whole Heartland thesis a fallacy from its very inception, and argues that this resilient fallacy continues to distort perceptions and policies in/on Central Asia. Second, it draws attention to t...

  7. Dry needling — peripheral and central considerations

    OpenAIRE

    Dommerholt, Jan

    2011-01-01

    Dry needling is a common treatment technique in orthopedic manual physical therapy. Although various dry needling approaches exist, the more common and best supported approach targets myofascial trigger points. This article aims to place trigger point dry needling within the context of pain sciences. From a pain science perspective, trigger points are constant sources of peripheral nociceptive input leading to peripheral and central sensitization. Dry needling cannot only reverse some aspects...

  8. Ocelot (Leopardus pardalis) Density in Central Amazonia

    OpenAIRE

    Daniel Gomes da Rocha; Rahel Sollmann; Emiliano Esterci Ramalho; Renata Ilha; Tan, Cedric K. W.

    2016-01-01

    Ocelots (Leopardus pardalis) are presumed to be the most abundant of the wild cats throughout their distribution range and to play an important role in the dynamics of sympatric small-felid populations. However, ocelot ecological information is limited, particularly for the Amazon. We conducted three camera-trap surveys during three consecutive dry seasons to estimate ocelot density in Amanã Reserve, Central Amazonia, Brazil. We implemented a spatial capture-recapture (SCR) model that shared ...

  9. Fragile isthmus under pressure. Central America.

    Science.gov (United States)

    Ypsilantis, J

    1992-01-01

    In Costa Rica the 1300 hectares of rainforest that comprise La Selva Biological Station support more than 1.5 times the number of plant and animal species found in California. In Central America over 2/3 of all deforestation has occurred since 1950, and closed canopy forest has shrunk dramatically during the past 40 years. The population in Central America, plus Mexico, grew by around 28% during the period 1977-87. At the same time the surface of forests and woodlands decreased by 13%, to 26% of the total land area. Croplands grew by 4% during these 10 years, to 13% of the total land area, and pastures by 2% to 37%; and unproductive lands grew by 14% to 24% of total land area. 50% of land is seriously eroded or degraded in El Salvador and over 30% in Guatemala. Central America's population was 22 million in 1980, 29 million in 1990, and it is anticipated to reach 63 million by 2025. Central America's urban population reached 46% in the 1990s: over 13 million with continuing increases in the next few decades. The growing population's need for fuelwood and the demand for agricultural land pose the main threat to forests in the coming decades. Close to 90% of the energy used by households comes from fuelwood. In the Telire reserve in Costa Rica 366 Cabecars are not yet an environmental threat for the forest. The Peten area in Guatemala is inhabited by around 300,000 people whose destructive slash and burn practices pose a serious threat to the environment which is exacerbated by a high population growth rate of 5.5% a year. PMID:12317701

  10. Scripts and politics in modern Central Europe

    OpenAIRE

    Kamusella, Tomasz Dominik

    2012-01-01

    At present two scripts are employed in Central Europe, Latin and Cyrillic, or three,if we include Greece in the region. In this article I set out to problematise this oversimplisticpicture drawing at examples from the past and pointing to various politicaland identificational uses of scripts today. Until the mid-20th century, also other scripts(and different types of the Latin and Cyrillic script, for that matter) were used forofficial purposes and in book production, namely Arabic, Armenian,...

  11. Central serous chorioretinopathy: a pathogenetic model

    OpenAIRE

    et al; Manuela Imparato; Filippo Romanazzi; Antonio Caccavale

    2011-01-01

    Antonio Caccavale1, Filippo Romanazzi1, Manuela Imparato1, Angelo Negri2, Anna Morano3, Fabio Ferentini21Department of Ophthalmology, Neuropthalmology and Ocular Immunology Service, 2Department of Ophthalmology, Hospital “C. Cantù”, Abbiategrasso, Milan, Italy; 3University Eye Clinic, Foundation IRCCS San Matteo Hospital, Pavia, ItalyAbstract: Despite numerous studies describing predominantly its demography and clinical course, many aspects of central serous cho...

  12. Central Planning and Monetarism: Fellow Travelers?

    OpenAIRE

    Richard Portes

    1981-01-01

    We discuss the monetary institutions and macroeconomics of centrally planned economies (CPEs) ; objectives and techniques of monetary control; the relevance to CPEs of the neutrality property, the natural rate hypothesis, and the quantity theory; the roles of stock .and flow variables and the stability of asset demand and expenditure functions; the relation between monetary policy, fiscal policy and incomes policy in CPEs; the CPE equivalent of a floating exchange rate and its implications fo...

  13. DNA, the central molecule of aging.

    Science.gov (United States)

    Lenart, Peter; Krejci, Lumir

    2016-04-01

    Understanding the molecular mechanism of aging could have enormous medical implications. Despite a century of research, however, there is no universally accepted theory regarding the molecular basis of aging. On the other hand, there is plentiful evidence suggesting that DNA constitutes the central molecule in this process. Here, we review the roles of chromatin structure, DNA damage, and shortening of telomeres in aging and propose a hypothesis for how their interplay leads to aging phenotypes.

  14. Visibility of the central canal on MRI

    Energy Technology Data Exchange (ETDEWEB)

    Petit-Lacour, M.C.; Lasjaunias, P.; Iffenecker, C.; Benoudiba, F.; Hadj Rabia, M.; Doyon, D. [Service de Neuroradiologie, Faculte de Paris Sud (France); Hurth, M. [Department of Neurosurgery, Faculte Paris Sud, Kremlin-Bicetre (France)

    2000-10-01

    The central canal of the spinal cord is present at birth and becomes progressively obliterated. Cadaver studies have shown that it may persiste partially or completely. To our knowledge, this entity has not been described on MRI. We reviewed 794 MRI studies of the spinal cord, and found 12 patients (aged 14 to 65 years) who had an intramedullary cavity. The cavity was at the junction of the ventral {sup 1}/{sub 3} and dorsal {sup 2}/{sub 3} of the spinal cord, except at the level of the lumbar enlargement, where it was central. It was filiform in most cases, although sometimes fusiform (3 to 4 mm in diameter), and had regular contours. The cavity were thoracic in 69 % of cases. The clinical features were totally unrelated to the image, and there were no anatomical factors (Chiari malformation, dysraphism) predisposing to syringomyelia. The images were perfectly compatible with a persistent central canal, which we interpret as a variant of normal anatomy. Therefore it is important to regard these findings as normal, to avoid unnecessary treatment and follow-up. (orig.)

  15. LANDSAT imagery of the Central Andes

    Science.gov (United States)

    Komer, C. A.; Morgan, P.

    1986-01-01

    The central Andes of South America extend from approximately 14 deg. S to 28 deg. S as an unbroken chain of mountains and volcanoes over 2000 km long. It is here that the Nazca plate dives under the South American plate at angles varying from 10 deg to 30 deg. Very little is known about the volcanoes comprising this classic, subduction-type plate margin. A catalogue of the volcanoes in the central Andes is being prepared by Dr. P.W. Francis and Dr. C.A. Wood at the NASA Lunar and Planetary Institute. At present, more than 800 volcanoes of Cenozoic age have been recognized in the chain, with an estimated 75-80 major, active Quarternary volcanoes. Approximately one hundred 1536 x 1536 pixel color composite Optronics positives were produced from six full LANDSAT Thermatic Mapper scenes and three partial TM scenes. These positives cover a large portion of the central Andes. The positives were produced from LANDSAT data using the VAX imaging package, LIPS. The scenes were first transferred from magnetic tape to disk. The LIPS package was then used to select volcanically interesting areas which were then electronically enhanced. Finally, the selected areas were transferred back to tape and printed on the Optronics equipment. The pictures are color composites using LANDSAT TM bands 7,4, and 2 in the red, green, and blue filters, respectively.

  16. Temporal diversification of Central American cichlids

    Directory of Open Access Journals (Sweden)

    Hulsey C Darrin

    2010-09-01

    Full Text Available Abstract Background Cichlid fishes are classic examples of adaptive radiation because of their putative tendency to explosively diversify after invading novel environments. To examine whether ecological opportunity increased diversification (speciation minus extinction early in a species-rich cichlid radiation, we determined if Heroine cichlids experienced a burst of diversification following their invasion of Central America. Results We first reconstructed the Heroine phylogeny and determined the basal node to use as the root of Central American Heroine diversification. We then examined the influence of incomplete taxon sampling on this group's diversification patterns. First, we added missing species randomly to the phylogeny and assessed deviations from a constant rate of lineage accumulation. Using a range of species numbers, we failed to recover significant deviations from a pure-birth process and found little support for an early burst of diversification. Then, we examined patterns of lineage accumulation as nodes were increasingly truncated. We assumed that as we removed more recently diverged lineages that sampling would become more complete thereby increasing the power to detect deviations from a pure-birth model. However, truncation of nodes provided even less support for an early burst of diversification. Conclusions Contrary to expectations, our analyses suggest Heroine cichlids did not undergo a burst of diversification when they invaded from South America. Throughout their history in Central America, Heroine cichlids appear to have diversified at a constant rate.

  17. Decreased central corneal thickness in ankylosing spondylitis.

    Science.gov (United States)

    Ortak, Huseyin; Inanır, Ahmet; Demir, Selim; Uysal, Alper; Şahin, Şafak; Sağcan, Mustafa; Önder, Yalçın; Alim, Sait; Demir, Ayşe Kevser

    2014-04-01

    Central corneal thickness and dry eye tests were evaluated in a study population consisting of 68 ankylosing spondylitis patients diagnosed according to the modified New York criteria, and 61 age-matched controls without ankylosing spondylitis. A full ophthalmological evaluation was performed on each subject. All subjects were screened for age, gender, HLA-B27, tear break-up time test, Schirmer test, and duration of disease. Central corneal thickness was measured under topical anesthesia with an ultrasonic pachymeter. The mean central corneal thickness was 537.3 ± 30.6 μm, range 462-600 μm, in ankylosing spondylitis patients, whereas it was 551.7 ± 25.2 μm, range 510-620 μm, in controls (p = 0.005). The Schirmer test result was 7.3 ± 5.9 mm for the ankylosing spondylitis patients and 11.7 ± 5.8 mm for the control group (p = 0.002). Tear break-up time was 7.3 ± 3.2 s for the ankylosing spondylitis patients and 14.0 ± 4.5 s for the control group (p ankylosing spondylitis. In addition, attention must be given to lower dry eye tests in surgical interventions such as photorefractive keratectomy and laser in situ keratomileusis in ankylosing spondylitis patients.

  18. The ATLAS Level-1 Central Trigger

    CERN Document Server

    Stockton, M; The ATLAS collaboration

    2011-01-01

    The ATLAS Level-1 trigger system is responsible for reducing the anticipated LHC collision rate from 40 MHz to less than 100 kHz. This Level-1 selection identifies, jet, tau/hadron, electron/photon and muon candidates, with additional triggers for missing and total energy. These inputs are used by the Level-1 Central Trigger to form a Level-1 Accept decision. This decision, along with summary information, is then passed into the higher levels of the trigger system and sub-detectors, which also receive the clock from the Level-1 Central trigger. The performance of the Central Trigger during the first collisions will be shown. This includes details of how the trigger information, along with dead-time rates, are monitored and logged by the online system for physics analysis, data quality assurance and operational debugging. Also presented are the software tools used to efficiently display the relevant information in the control room in a way useful for shifters and experts.

  19. Plants and the central nervous system.

    Science.gov (United States)

    Carlini, E A

    2003-06-01

    This review article draws the attention to the many species of plants possessing activity on the central nervous system (CNS). In fact, they cover the whole spectrum of central activity such as psychoanaleptic, psycholeptic and psychodysleptic effects, and several of these plants are currently used in therapeutics to treat human ailments. Among the psychoanaleptic (stimulant) plants, those utilized by human beings to reduce body weight [Ephedra spp. (Ma Huang), Paullinia spp. (guaraná), Catha edulis Forssk. (khat)] and plants used to improve general health conditions (plant adaptogens) were scrutinized. Many species of hallucinogenic (psychodysleptic) plants are used by humans throughout the world to achieve states of mind distortions; among those, a few have been used for therapeutic purposes, such as Cannabis sativa L., Tabernanthe iboga Baill. and the mixture of Psychotria viridis Ruiz and Pav. and Banisteriopsis caapi (Spruce ex Griseb.) C.V. Morton. Plants showing central psycholeptic activities, such as analgesic or anxiolytic actions (Passiflora incarnata L., Valeriana spp. and Piper methysticum G. Forst.), were also analysed.Finally, the use of crude or semipurified extracts of such plants instead of the active substances seemingly responsible for their therapeutic effect is discussed. PMID:12895668

  20. The Centralizer on H- Separable Smash Products

    Institute of Scientific and Technical Information of China (English)

    祝家贵

    2002-01-01

    Let H be a finite dimensional Hopf algebra over a field and A an H-module algebra. The H induces an action on the CA#H(A) by adjoint and CA#H(A)H= Z(A # H) = C,where CA#H(A) denotes the centralizer which algebra A in A # H and Z(A # H) the center of A # H.The aim of this paper is to discuss ,the Galois conditions on the centralizer CA# H(A).We prove that CA# H(A)/ZA # H is H* -Galois if and only if CA# H(A)# H/CA# H(A) is H-separable). Furthermore , if H is a finite dimensional semisimple Hopf algebra and CA# H(A)# H is an Azumaya C-algebra or A # H/A is H-separable, CA# H(A) satisfies the double centralizer property in CA# H(A)# H, CA# H(A)/C is separable and there exists a cocommutative left integral t ∈∫1H,then CA# H(A)/C is H*-Galois.

  1. A Quaternary fault database for central Asia

    Science.gov (United States)

    Mohadjer, Solmaz; Ehlers, Todd Alan; Bendick, Rebecca; Stübner, Konstanze; Strube, Timo

    2016-02-01

    Earthquakes represent the highest risk in terms of potential loss of lives and economic damage for central Asian countries. Knowledge of fault location and behavior is essential in calculating and mapping seismic hazard. Previous efforts in compiling fault information for central Asia have generated a large amount of data that are published in limited-access journals with no digital maps publicly available, or are limited in their description of important fault parameters such as slip rates. This study builds on previous work by improving access to fault information through a web-based interactive map and an online database with search capabilities that allow users to organize data by different fields. The data presented in this compilation include fault location, its geographic, seismic, and structural characteristics, short descriptions, narrative comments, and references to peer-reviewed publications. The interactive map displays 1196 fault traces and 34 000 earthquake locations on a shaded-relief map. The online database contains attributes for 123 faults mentioned in the literature, with Quaternary and geodetic slip rates reported for 38 and 26 faults respectively, and earthquake history reported for 39 faults. All data are accessible for viewing and download via http://www.geo.uni-tuebingen.de/faults/. This work has implications for seismic hazard studies in central Asia as it summarizes important fault parameters, and can reduce earthquake risk by enhancing public access to information. It also allows scientists and hazard assessment teams to identify structures and regions where data gaps exist and future investigations are needed.

  2. Temporal node centrality in complex networks.

    Science.gov (United States)

    Kim, Hyoungshick; Anderson, Ross

    2012-02-01

    Many networks are dynamic in that their topology changes rapidly--on the same time scale as the communications of interest between network nodes. Examples are the human contact networks involved in the transmission of disease, ad hoc radio networks between moving vehicles, and the transactions between principals in a market. While we have good models of static networks, so far these have been lacking for the dynamic case. In this paper we present a simple but powerful model, the time-ordered graph, which reduces a dynamic network to a static network with directed flows. This enables us to extend network properties such as vertex degree, closeness, and betweenness centrality metrics in a very natural way to the dynamic case. We then demonstrate how our model applies to a number of interesting edge cases, such as where the network connectivity depends on a small number of highly mobile vertices or edges, and show that our centrality definition allows us to track the evolution of connectivity. Finally we apply our model and techniques to two real-world dynamic graphs of human contact networks and then discuss the implication of temporal centrality metrics in the real world. PMID:22463279

  3. Peritoneal dissemination from central neurocytoma: case report

    Directory of Open Access Journals (Sweden)

    Coelho Neto Maurício

    2003-01-01

    Full Text Available OBJECTIVE: central neurocytoma is a low grade tumor of neuroglial origin and a relatively new histological entity. Only a few cases have been reported and its biological behavior is still uncertain. Some cases have shown an aggressive behavior (local recurrence, malignant dedifferentiation or CSF dissemination and challenged the initial view of its relative benignity. A case of central neurocytoma with peritoneal dissemination is presented. CASE: a six years-old boy with recurrent neurocytoma of III ventricle and left thalamus showed fast growth of tumor rest and ascites three and a half years after subtotal removal of the lesion. Tumor cells were identified in the ascitic fluid and implanted in the peritoneum. Chemotherapy was initiated immediately after diagnosis of peritoneal dissemination (etoposide, carboplatin, doxorubicin and cyclophosphamide. The patient developed metabolic imbalance and respiratory failure due to rapid formation of ascitic fluid and died 3 days after the diagnosis of peritoneal dissemination was established. CONCLUSION: central neurocytoma is a low grade tumor with low values of the proliferative index in the majority of cases. In spite of that, some tumors may present a very aggressive behavior and extraneural dissemination. Evaluation of proliferative index may be a guideline parameter for planning adjuvant therapies after surgical treatment in selected cases. Extraneural dissemination may occur in some cases specially in patients with ventriculoperitoneal shunt.

  4. The ATLAS level-1 Central Trigger

    CERN Document Server

    Spiwoks, R; Berge, D; Caracinha, D; Ellis, Nick; Farthouat, P; Gällnö, P; Haas, S; Klofver, P; Krasznahorkay, A; Messina, A; Ohm, C; Pauly, T; Perantoni, M; Pessoa Lima Junior, H; Schuler, G; De Seixas, J M; Wengler, T; PH-EP

    2007-01-01

    The ATLAS Level-1 Central Trigger consists of the Muon-to-Central-Trigger-Processor Interface (MUCTPI), the Central Trigger Processor (CTP), and the Timing, Trigger and Control (TTC) partitions of the sub-detectors. The MUCTPI connects the output of the muon trigger system to the CTP. At every bunch crossing it receives information on muon candidates from each of the 208 muon trigger sectors and calculates the total multiplicity for each of six pT thresholds. The CTP combines information from the calorimeter trigger and the MUCTPI and makes the final Level-1 Accept (L1A) decision on the basis of lists of selection criteria (trigger menus). The MUCTPI and the CTP provide trigger summary information to the Level-2 trigger and to the data acquisition (DAQ) for every event selected at the Level-1. They further provide accumulated and, for the CTP, bunch-by-bunch counter data for monitoring of the trigger, detector and beam conditions. The TTC partitions send timing, trigger and control signals from the CTP to the...

  5. Is Centrality the Key to High Performance?

    Directory of Open Access Journals (Sweden)

    Eckenhofer Eva Maria

    2010-12-01

    Full Text Available Social Capital, the outcome for individuals from networks with shared norms and values, has already been discussed as a driver for innovation and performance improvement. Social Capital is a resource embedded in social structures, which can be accessed as well as mobilized in purposeful actions. There are various theories about social resources and structures leading to discussions on whether network closure or the absence of ties is the key to the success of Social Capital. Nevertheless, little is known about the relationship between network centrality and Social Capital. Therefore, this paper aims at contributing to the discussion by analyzing, using a case study, the structural position of actors who are rich in Social Capital. The study also assesses if the actors who are central in the social network are the ones with the highest performance. This study was based on a survey of 170 students from a Czech University, who form three different networks. For the detection of Social Capital, a procedure developed and tested in the European Values Study Surveys was applied. The relational data was analyzed using UCINET and illustrated with the use of VISONE. The outcomes suggest that there is a connection between the centrality of an actor and their performance, not only in terms of average grade but also Social Capital. Furthermore, the data analysis shows that the number of languages an actor speaks as well as experiences in foreign countries impacts on their performance and location within a network.

  6. Health, vital goals, and central human capabilities.

    Science.gov (United States)

    Venkatapuram, Sridhar

    2013-06-01

    I argue for a conception of health as a person's ability to achieve or exercise a cluster of basic human activities. These basic activities are in turn specified through free-standing ethical reasoning about what constitutes a minimal conception of a human life with equal human dignity in the modern world. I arrive at this conception of health by closely following and modifying Lennart Nordenfelt's theory of health which presents health as the ability to achieve vital goals. Despite its strengths I transform Nordenfelt's argument in order to overcome three significant drawbacks. Nordenfelt makes vital goals relative to each community or context and significantly reflective of personal preferences. By doing so, Nordenfelt's conception of health faces problems with both socially relative concepts of health and subjectively defined wellbeing. Moreover, Nordenfelt does not ever explicitly specify a set of vital goals. The theory of health advanced here replaces Nordenfelt's (seemingly) empty set of preferences and society-relative vital goals with a human species-wide conception of basic vital goals, or 'central human capabilities and functionings'. These central human capabilities come out of the capabilities approach (CA) now familiar in political philosophy and economics, and particularly reflect the work of Martha Nussbaum. As a result, the health of an individual should be understood as the ability to achieve a basic cluster of beings and doings-or having the overarching capability, a meta-capability, to achieve a set of central or vital inter-related capabilities and functionings.

  7. Temporal node centrality in complex networks

    Science.gov (United States)

    Kim, Hyoungshick; Anderson, Ross

    2012-02-01

    Many networks are dynamic in that their topology changes rapidly—on the same time scale as the communications of interest between network nodes. Examples are the human contact networks involved in the transmission of disease, ad hoc radio networks between moving vehicles, and the transactions between principals in a market. While we have good models of static networks, so far these have been lacking for the dynamic case. In this paper we present a simple but powerful model, the time-ordered graph, which reduces a dynamic network to a static network with directed flows. This enables us to extend network properties such as vertex degree, closeness, and betweenness centrality metrics in a very natural way to the dynamic case. We then demonstrate how our model applies to a number of interesting edge cases, such as where the network connectivity depends on a small number of highly mobile vertices or edges, and show that our centrality definition allows us to track the evolution of connectivity. Finally we apply our model and techniques to two real-world dynamic graphs of human contact networks and then discuss the implication of temporal centrality metrics in the real world.

  8. Tuberculoma of the central nervous system.

    Science.gov (United States)

    DeLance, Arthur R; Safaee, Michael; Oh, Michael C; Clark, Aaron J; Kaur, Gurvinder; Sun, Matthew Z; Bollen, Andrew W; Phillips, Joanna J; Parsa, Andrew T

    2013-10-01

    Tuberculosis is among the oldest and most devastating infectious diseases worldwide. Nearly one third of the world's population has active or latent disease, resulting in 1.5 million deaths annually. Central nervous system involvement, while rare, is the most severe form of tuberculosis. Manifestations include tuberculoma and tuberculous meningitis, with the majority of cases occurring in children and immunocompromised patients. Despite advancements in imaging and laboratory diagnostics, tuberculomas of the central nervous system remain a diagnostic challenge due to their insidious nature and nonspecific findings. On imaging studies tuberculous meningitis is characterized by diffuse basal enhancement, but tuberculomas may be indistinguishable from neoplasms. Early diagnosis is imperative, since clinical outcomes are largely dependent on timely treatment. Stereotactic biopsy with histopathological analysis can provide a definitive diagnosis, but is only recommended when non-invasive methods are inconclusive. Standard medical treatment includes rifampicin, isoniazid, pyrazinamide, and streptomycin or ethambutol. In cases of drug resistance, revision of the treatment regimen with second-line agents is recommended over the addition of a single drug to the first-line regimen. Advances in genomics have identified virulent strains of tuberculosis and are improving our understanding of host susceptibility. Neurosurgical referral is advised for patients with elevated intracranial pressure, seizures, or brain or spinal cord compression. This review synthesizes pertinent findings in the literature surrounding central nervous system tuberculoma in an effort to highlight recent advances in pathophysiology, diagnosis, and treatment.

  9. Nuclear energy options for Central Asia

    International Nuclear Information System (INIS)

    Full text: The five countries of Central Asia have a strong basis for the development of commercial nuclear energy. Several test reactors have operated within the region, including the Ak tau BN350 - a very advanced fast breeder reactor combined with a large water desalination plant. The Central Asian countries have a large cadre of well-trained nuclear scientists and engineers who could operate and maintain nuclear power plants and expanded nuclear fuel infrastructure as they evolve. The Central Asia region experiences significant demand for base-load energy in major population centers and industrial development areas. A well-developed electricity transmission grid could transmit nuclear-generated electricity from the power stations to the load centers. Finally, given the large land area and the relatively small population (in relation to the size of the region) there exist many remote and stable sites where nuclear generation centers can be sited and connected to the transmission grid. A good example is the Semipalatinsk Nuclear Test Site (STS) whose vast area could easily contain several nuclear power plants, which would be cooled by the water flow of the Irtish River. The Kazakhstan authorities have already identified several potential nuclear power plant sites within the national transmission system, the STS being one such prospective site. The large-scale availability of uranium in the region affords the uranium exporting countries - particularly Kazakhstan and Uzbekistan - significant leverage with international nuclear reactor vendors in establishing the terms for nuclear plant imports into the region. Such leverage could further be increased if multiple reactor orders are submitted, for instance by two or more countries ordering similar types of plants to be installed at various sites in their territories. The added value of the uranium exports from Central Asia does not have to be measured only in terms of supporting the development of fuel cycle

  10. Comparing Central Peak and Central Pit Craters on Mercury and Mars: Implications for Crustal Strength

    Science.gov (United States)

    Barlow, Nadine G.; Horstman, Ryan M.

    2016-10-01

    We have measured and classified 20,782 impact craters on Mercury and 24,495 craters on Mars 5 km in diameter and larger for a comparison study of these features. We identified 1144 floor pit and 638 summit pit craters on Mars and 32 summit pit craters but no floor pits on Mercury. We also identified 1682 central peak craters on Mars and 1764 on Mercury. We computed the ratio of the pit or basal peak diameter to the crater diameter in each case and compared the results for the two bodies. Summit pits on Mars have a median pit-to-crater diameter (Dp/Dc) ratio of 0.12 compared to 0.09 on Mercury, indicating pits are slightly larger relative to their parent crater on Mars. We find no correlation of the distribution of Mercury's central pits with features attributed to volatiles, i.e. radar-bright polar craters and craters containing hollows. This indicates that Mercury's central pits form by collapse of a weak brecciated core in the central peak and do not require the presence of volatiles, as is commonly assumed for central pit formation. The median peak-to-crater diameter (Dpk/Dc) ratio for the peaks on which summit pits are found on both bodies is statistically identical to that of the respective normal unpitted central peaks. This indicates that the peaks on which summit pits occur form in the same manner as normal central peaks but subsequently undergo core collapse to create the summit pit. Interestingly, the median Dpk/Dc for Martian peaks is twice as high as for their Mercurian counterparts (0.30 versus 0.15, respectively). Because Mercury and Mars have essentially the same surface gravity, the only major difference between the two bodies that could explain this observation is target characteristics. Prior studies of the composition of the crust and the detection of larger-than-normal secondary craters have led to the proposal that Mercury's crust is stronger than the crusts of the other terrestrial planets. Mercury's low number of central pit craters, the

  11. Central Asian Gypsies: identities and migrations

    Directory of Open Access Journals (Sweden)

    Elena Marushiakova

    2015-12-01

    Full Text Available Central Asian Gypsies: identities and migrations During recent years the topic of Gypsy/Roma migration and identities became burning topic of pan-EUropean public discourse. Much less attention is paid to the Gypsy migrations outside the borders of European Union. The present article has ambitious goal to fulfill this gap and to present contemporary Gypsy migrations in Post-soviet Central Asian in order to see how this “burning” topic looks outside European space. After breakdown of Soviet Union and establishing of new independent republics in Central Asia and in connection to economical difficulties, wars and social unrest, in order to make their living, the communities of Central Asian ‘Gypsies’ revitalised their former nomadic traditions and migrate towards Russian Federation and in frames of Central Asia towards Kazakhstan. There they are earning their living through begging and sporadic work in construction and scrap collection. A central point of this article is the impact of these contemporary migrations on the development of identities and well being of Central Asian ‘Gypsies’. The multilevel, hierarchically structured identities of Central-Asian ‘Gypsies' are analysed as demonstrated in different historical contexts – as former “Soviet people”, member of former ruling class of agricultural proletariat, and as declassed community today; as Central-Asian ‘Gypsies’ or as citizens of respective Central Asian Republics during migrations in Russian Federation in front of Russian majority society and in front of Roma; and in context of the Central Asian region during the migrations to Kazakhstan and in their home countries.     Cyganie środkowoazjatyccy – tożsamości i migracje W ostatnich latach tematyka migracji i tożsamości Cyganów (Romów stała się tematem palącym w unijnoeuropejskim dyskursie publicznym. O wiele mniej uwagi poświęca się w nim migracjom Cyganów, które mają miejsce poza granicami

  12. Central Asian gas in Eurasian power game

    International Nuclear Information System (INIS)

    Following the dissolution of the Soviet Union, various gas pipeline projects have been proposed to diversify transit routes and export markets of the landlocked Central Asian states. To evaluate the pipeline project's impact on the players' bargaining power, I apply the cooperate game theory to a quantitative model of the Eurasian gas trade and quantify the bargaining power structure via the Shapley value. Due to ample production capacities in Central Asia, I observe little strategic interaction between the West and China. Thus, demand competition with China is not necessarily a disadvantage for the West, and the Turkmenistan–China pipeline does not affect the impact of the westbound projects aiming Europe and Turkey. For Turkmenistan, i.e., the main supplier in the region, a link via the Caspian Sea to Turkey is the most beneficial westbound option. Although the projects carrying gas from Azerbaijan and Turkmenistan to Europe enjoy the European Commission's political support, they yield marginal benefits to the European consumers. Thanks to its transit position, Turkey collects a large share of the benefits in the East–West gas trade. - Highlights: • The Eurasian gas trade is represented as a cooperative game which is solved with the Shapley value. • There is no demand competition between the West and China for Central Asian gas. • For Turkmenistan the route via the Caspian Sea is the most beneficial westbound pipeline option. • Turkey emerges as a transit country and collects a large share of the benefits from the East–West gas trade. • A link to Europe yields marginal benefits to Turkmenistan and Europe

  13. HIS Central and the Hydrologic Metadata Catalog

    Science.gov (United States)

    Whitenack, T.; Zaslavsky, I.; Valentine, D. W.

    2008-12-01

    The CUAHSI Hydrologic Information System project maintains a comprehensive workflow for publishing hydrologic observations data and registering them to the common Hydrologic Metadata Catalog. Once the data are loaded into a database instance conformant with the CUAHSI HIS Observations Data Model (ODM), the user configures ODM web service template to point to the new database. After this, the hydrologic data become available via the standard CUAHSI HIS web service interface, that includes both data discovery (GetSites, GetVariables, GetSiteInfo, GetVariableInfo) and data retrieval (GetValues) methods. The observations data then can be further exposed via the global semantics-based search engine called Hydroseek. To register the published observations networks to the global search engine, users can now use the HIS Central application (new in HIS 1.1). With this online application, the WaterML-compliant web services can be submitted to the online catalog of data services, along with network metadata and a desired network symbology. Registering services to the HIS Central application triggers a harvester which uses the services to retrieve additional network metadata from the underlying ODM (information about stations, variables, and periods of record). The next step in HIS Central application is mapping variable names from the newly registered network, to the terms used in the global search ontology. Once these steps are completed, the new observations network is added to the map and becomes available for searching and querying. The number of observations network registered to the Hydrologic Metadata Catalog at SDSC is constantly growing. At the time of submission, the catalog contains 51 registered networks, with estimated 1.7 million stations.

  14. Angiotensin II during experimentally simulated central hypovolemia

    Directory of Open Access Journals (Sweden)

    Theo Walther Jensen

    2016-03-01

    Full Text Available Abstract:Central hypovolemia, defined as diminished blood volume in the heart and pulmonary vascular bed, is still an unresolved problem from a therapeutic point of view. The development of pharmaceutical agents targeted at specific angiotensin II receptors, like the non-peptidergic AT2-receptor agonist compound 21, is yielding many opportunities to uncover more knowledge about angiotensin II receptor profiles and possible therapeutic use. Cardiovascular, anti-inflammatory and neuroprotective therapeutic use of compound 21 have been suggested. However, there has not yet been a focus on the use of these agents in a hypovolemic setting. We argue that the latest debates on the effect of angiotensin II during hypovolemia might guide for future studies investigating the effect of such agents during experimentally simulated central hypovolemia. The purpose of this review is to examine the role of angiotensin II during episodes of central hypovolemia.To examine this, we reviewed results from studies with three experimental models of simulated hypovolemia: head up tilt table test, lower body negative pressure, and hemorrhage of animals. A systemic literature search was made with the use of PubMed/MEDLINE for studies that measured variables of the renin-angiotensin system or its effect during simulated hypovolemia. 12 articles, using one of the three models, were included and showed a possible organ protective effect and an effect on the sympathetic system of angiotensin II during hypovolemia. The results support the possible organ protective vasodilatory role for the AT2-receptor during hypovolemia on both the kidney and the splanchnic tissue.

  15. The Case of NRENs in Central Asia

    Directory of Open Access Journals (Sweden)

    Robert Franciscus Janz

    2012-07-01

    Full Text Available National Research and Education Network organizations (NRENs provide advanced information and communication technology (ICT services for the academic community of their country. Their focus is often on providing affordable high speed bandwidth amongst their members and to other research networks, but NRENs also provide other advanced services such as electronic repositories, educational environments and supercomputing facilities. Higher Education and Research institutions have to play an active role in the transformation to the “Knowledge Society”. A recent (2010 report of the International Telecommunication Union has identified NRENs as important vehicles in reaching the goals of the World Summit of the Information Society. It is also demonstrated that the Central Asian countries score very low in the Networked Readiness Indices of the World Economic Forum, including areas where strong NRENs could improve the status quo. NRENs therefore have a role that is also important for the nation itself and therefore claims for government support are legitimate. About 62% of the countries of the world already have an NREN and there are four characteristics that are common to these NRENs. In nearly all of the cases the NREN is a not-for-profit organization that not only serves the academic community, but is also owned by the same community. Four out of five Central Asian countries have an active NREN and these NRENs all participate in the EC funded CAREN project that aims to set up a sustainable regional network for the academic communities in the participating countries. Today, the Central Asian Research and Education Network (CAREN is upgrading the ancient Silk Road to a 21st-century high-speed internet highway for research and educational institutions through the region. Operational since July 2010, CAREN currently interconnects scientists and students from Kazakhstan, Kyrgyzstan, Tajikistan, and Turkmenistan.

  16. Measured compaction for 24 extensometers in the Central Valley

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This digital dataset contains the compaction data for 24 extensometers used for observations in the Central Valley Hydrologic Model (CVHM). The Central Valley...

  17. Evapotranspiration Input Data for the Central Valley Hydrologic Model (CVHM)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This digital dataset contains monthly reference evapotranspiration (ETo) data for the Central Valley Hydrologic Model (CVHM). The Central Valley encompasses an...

  18. Septic arthritis in the central part of Denmark

    DEFF Research Database (Denmark)

    Asmussen Andreasen, Rikke; Andersen, Nanna Skaarup; Just, Søren Andreas;

    Septic arthritis in the central part of Denmark, Annals of the Rheumatic Diseases, volume 73, supplement 2, p. 287......Septic arthritis in the central part of Denmark, Annals of the Rheumatic Diseases, volume 73, supplement 2, p. 287...

  19. Distributed generation and centralized power system in Thailand

    DEFF Research Database (Denmark)

    Sukkumnoed, Decharut

    The paper examines and discusses conflicts between the development of distributed power and centralized power system in Thailand.......The paper examines and discusses conflicts between the development of distributed power and centralized power system in Thailand....

  20. Vasculitis Syndromes of the Central and Peripheral Nervous Systems

    Science.gov (United States)

    ... About NINDS Vasculitis Syndromes of the Central and Peripheral Nervous Systems Fact Sheet See a list of all NINDS ... 496-5717 "Vasculitis Syndromes of the Central and Peripheral Nervous Systems Fact Sheet", NINDS, Publication date July 2011. NIH ...

  1. D0 central tracking chamber performance studies

    Energy Technology Data Exchange (ETDEWEB)

    Pizzuto, D.

    1991-12-01

    The performance of the completed DO central tracking chamber was studied using cosmic rays at the State University of New York at Stony Brook. Also studied was a prototype tracking chamber identical in design to the completed DO tracking chamber. The prototype chamber was exposed to a collimated beam of 150 GeV pions at the Fermilab NWA test facility. Results indicate an R{Phi} tracking resolution compatible with the limitations imposed by physical considerations, excellent 2 track resolution, and a high track reconstruction efficiency along with a good rejection power against {gamma} {yields} e {sup +} e{sup {minus}} events.

  2. Sources of Economic Fluctuations in Central America

    Directory of Open Access Journals (Sweden)

    Wilfredo Toledo

    2014-06-01

    Full Text Available Using panel data from Central America, this paper studies the determining factors of inflation and aggregate output fluctuations by estimating two Structural Vector Autoregressive (SVAR models. Price and output variables are included in one of the models, whereas M2 and the price of oil are additional variables in the other one. Findings of this study suggest that price is determined by the demand, while output seems to be influenced mainly by the supply shocks in that area. It was also evidenced that the price of oil does not have a significant impact on the general price level in that region.

  3. An air quality model for Central Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Jazcilevich, D. Aron; Garcia, R. Agustin; Suarez, Gerardo Ruiz; Magana, R. Victor; Perez, L. Jose Luis [Universidad Nacional Autonoma de Mexico, Centro de Ciencias de la Atmosfera, Mexico City (Mexico); Fuentes-Gea, Vicente [Universidad Nacional Autonoma de Mexico, Div. de Estudios del Posgrado, Mexico City (Mexico)

    1999-07-01

    A computational air quality model for Central Mexico that includes the Basin of the Valley of Mexico, the Valleys of Toluca, Puebla and Cuernavaca already in experimental operation, is presented. The meteorology of the region is obtained combining two non-hydrostatic models: a model designed for synoptic scales called MM5 provides initial and boundary data to a model specially designed for urban environments and scales called MEMO. The transport model used numerical techniques developed by the authors that eliminate numerical diffusion and dispersion. For the photochemical model several ODE's integrators were tested. The emissions model developed uses the latest inventory data gathered in the region. (Author)

  4. Central waste complex interim safety basis

    Energy Technology Data Exchange (ETDEWEB)

    Cain, F.G.

    1995-05-15

    This interim safety basis provides the necessary information to conclude that hazards at the Central Waste Complex are controlled and that current and planned activities at the CWC can be conducted safely. CWC is a multi-facility complex within the Solid Waste Management Complex that receives and stores most of the solid wastes generated and received at the Hanford Site. The solid wastes that will be handled at CWC include both currently stored and newly generated low-level waste, low-level mixed waste, contact-handled transuranic, and contact-handled TRU mixed waste.

  5. Central Banking for Financial Stability in Asia

    OpenAIRE

    Kawai, Masahiro; Peter J. Morgan

    2012-01-01

    A key lesson of the 2007–2009 global financial crisis (GFC) was the importance of containing systemic financial risk and the need for a “macroprudential†approach to surveillance and regulation that can identify system-wide risks and take appropriate actions to maintain financial stability. By virtue of their overview of the economy and the financial system and their responsibility for payments and settlement systems, there is a broad consensus that central banks should play a key rol...

  6. Central Odontogenic Fibroma of the Mandible

    Directory of Open Access Journals (Sweden)

    Saeedeh Khajeh Ahmadi

    2013-01-01

    Full Text Available A 16-years-old female patient with painless swelling of the right side of mandible is described. She noticed the swelling from two years ago, without painful symptoms. Axial CT imaging showed buccal expansion with intact buccal and lingual cortical bone. The report of incisional biopsy was central odontogenic fibroma. Under general anesthesia the lesion was removed after ostectomy of buccal cortical plate and inferior alveolar nerve preserved. Three-year follow-up after tumor excision relieved no recurrence.

  7. Attitudes Concerning Wind Energy in Central Illinois

    OpenAIRE

    Theron, Sophie; Winter, J. Randy; David G. Loomis; Spaulding, Aslihan D.

    2011-01-01

    Energy consumption in the United Sates has been increasing and the cost of fossil fuels has been unstable in recent years. Expanding investment in renewable energy is one way to reduce the nation’s dependence on fossil fuels. However, the Not-In-My-Back- Yard (NIMBY) opposition and various concerns raised at public hearings may inhibit the expansion of wind energy in Illinois. This study aims to characterize the public beliefs and opinions toward wind energy in central Illinois.

  8. Performance evaluation of Central European companies

    Directory of Open Access Journals (Sweden)

    Petr Fiala

    2015-10-01

    Full Text Available The paper presents a modelling approach for performance comparison of Central European companies on three levels: country, industry, and company. The approach is based on Data Envelopment Analysis and Analytic Hierarchy Process. The proposed model consists of two basic sections. The first section estimates the importance of selected industries in the countries, whereas the second section evaluates the performance of companies within industries. The results of both sections are synthesized and finally the country performance is estimated. The evaluation is based on the data set resulting from a survey of companies from selected industries.

  9. Central Limit Theorem for Nonlinear Hawkes Processes

    CERN Document Server

    Zhu, Lingjiong

    2012-01-01

    Hawkes process is a self-exciting point process with clustering effect whose jump rate depends on its entire past history. It has wide applications in neuroscience, finance and many other fields. Linear Hawkes process has an immigration-birth representation and can be computed more or less explicitly. It has been extensively studied in the past and the limit theorems are well understood. On the contrary, nonlinear Hawkes process lacks the immigration-birth representation and is much harder to analyze. In this paper, we obtain a functional central limit theorem for nonlinear Hawkes process.

  10. D0 central tracking chamber performance studies

    International Nuclear Information System (INIS)

    The performance of the completed DO central tracking chamber was studied using cosmic rays at the State University of New York at Stony Brook. Also studied was a prototype tracking chamber identical in design to the completed DO tracking chamber. The prototype chamber was exposed to a collimated beam of 150 GeV pions at the Fermilab NWA test facility. Results indicate an RΦ tracking resolution compatible with the limitations imposed by physical considerations, excellent 2 track resolution, and a high track reconstruction efficiency along with a good rejection power against γ → e + e- events

  11. Smoothed dynamics in the central field problem

    OpenAIRE

    Santoprete, Manuele; Stoica, Cristina

    2009-01-01

    Consider the motion of a material point of unit mass in a central field determined by a homogeneous potential of the form $(-1/r^{\\alpha})$, $\\alpha>0,$ where $r$ being the distance to the centre of the field. Due to the singularity at $r=0,$ in computer-based simulations, usually, the potential is replaced by a similar potential that is smooth, or at least continuous. In this paper, we compare the global flows given by the smoothed and non-smoothed potentials. It is shown that the two flows ...

  12. CHL 01-2 CENTRAL HYPERTENSION.

    Science.gov (United States)

    Chen, Chen-Huan

    2016-09-01

    Blood pressure (BP) is conventionally measured with a pressure cuff over an upper arm and a cutoff of 140/90 mmHg in the office is the current criteria for diagnosing hypertension. Recently, out of office BP has been suggested as the reference standard for the management of hypertension, due to its better prognostic value over office BP.However, the above BP parameters are all measured at brachial arteries and may be different from the central blood pressure (CBP) measured in the ascending aorta or carotid arteries. The individual discrepancies between CBP and peripheral BP may be substantial and highly variable, and may magnify during hemodynamic changes or after pharmacological interventions. Growing evidence suggests that central BP may be more relevant than peripheral BP in predicting target organ damage and cardiovascular outcomes, central and peripheral BP may respond differently to antihypertensive medication in randomized controlled trials, and end-organ changes after antihypertensive medication are more strongly related to changes in central BP than peripheral BP.Currently,_ENREF_2_ENREF_5 non-invasive CBP can be obtained with either tonometry-based or cuff-based techniques. Using an outcome-driven approach to examine the discriminatory ability of CBP for long-term cardiovascular outcomes, an operational threshold for CBP has been derived and validated in two independent Taiwanese cohorts. A CBP cutoff, 130/90 mmHg, was characterized by a greater discriminatory power for long-term events, and can be considered to be implemented for the management of hypertension in routine daily clinical practice. CBP may have greater sensitivity and negative predictive value than peripheral BP in the diagnosis of hypertension. In the recently updated hypertension management guidelines, we have made a Level IIb recommendation that Measurement of CBP with a cutoff of 130/90 mmHg is recommended when a diagnosis of hypertension is clinically suspected but cannot be

  13. Discos en estrellas centrales de nebulosas planetarias

    Science.gov (United States)

    Saker, L.; Gómez, M.

    2016-08-01

    With the aim of investigating the possible existence of disks in the central stars of planetary nebulae (CSPN), in this contribution we present the spectral energy distributions of ten CSPN that show infrared (IR) excesses. Basic parameters of the disks such as internal radius and temperature are derived. When comparing the characteristics of these disks with the previously found around white dwarfs, it was found that the latter are significantly smaller. The disk sizes are compared with associated nebula. In general, disks are very compact and small in relation to the characteristic dimension of the nebula.

  14. Central Nervous System Complications of Oncologic Therapy.

    Science.gov (United States)

    Hoeffner, Ellen G

    2016-08-01

    Traditional and newer agents used to treat cancer can cause significant toxicity to the central nervous system. MRI of the brain and spine is the imaging modality of choice for patients with cancer who develop neurologic symptoms. It is important to be aware of the agents that can cause neurotoxicity and their associated imaging findings so that patients are properly diagnosed and treated. In some instances conventional MRI may not be able to differentiate posttreatment effects from disease progression. In these instances advanced imaging techniques may be helpful, although further research is still needed. PMID:27444003

  15. Pathology of the Trachea and Central Bronchi.

    Science.gov (United States)

    Shroff, Girish S; Ocazionez, Daniel; Vargas, Daniel; Carter, Brett W; Wu, Carol C; Nachiappan, Arun C; Gupta, Pushpender; Restrepo, Carlos S

    2016-06-01

    A wide variety of disorders can affect the trachea and central bronchi. Computed tomography is the imaging modality of choice in the evaluation of tracheobronchial disease. Tracheobronchial abnormalities are sometimes incidentally detected on routine imaging or when imaging is performed for another reason. Abnormalities of the tracheobronchial tree, however, can be easily missed because they can be subtle. Furthermore, because symptoms in patients with tracheobronchial disorders often overlap symptoms of lung disease, radiologists may focus their attention on the lungs and overlook the tracheobronchial tree. In this article, we review a wide range of tracheobronchial diseases with emphasis on their computed tomographic appearances.

  16. Central Waste Complex (CWC) Waste Analysis Plan

    International Nuclear Information System (INIS)

    The purpose of this waste analysis plan (WAP) is to document the waste acceptance process, sampling methodologies, analytical techniques, and overall processes that are undertaken for waste accepted for storage at the Central Waste Complex (CWC), which is located in the 200 West Area of the Hanford Facility, Richland, Washington. Because dangerous waste does not include the source, special nuclear, and by-product material components of mixed waste, radionuclides are not within the scope of this documentation. The information on radionuclides is provided only for general knowledge

  17. Vitamin D Status in Central Europe

    OpenAIRE

    Pawel Pludowski; Grant, William B; Harjit Pal Bhattoa; Milan Bayer; Vladyslav Povoroznyuk; Ema Rudenka; Heorhi Ramanau; Szabolcs Varbiro; Alena Rudenka; Elzbieta Karczmarewicz; Roman Lorenc; Justyna Czech-Kowalska; Jerzy Konstantynowicz

    2014-01-01

    Little published information is available regarding epidemiological data on vitamin D status in the large geographical region of Central Europe (CE). We searched the journal literature with regard to 25(OH)D concentrations among community-dwelling or healthy people living in CE. 25(OH)D concentrations varied by age, season, study sample size, and methodological approach [i.e., 25(OH)D assay used]. Concentrations of 25(OH)D in CE appeared lower than 30 ng/mL, and the magnitude of hypovitaminos...

  18. The trade off between central bank independence and conservativeness

    OpenAIRE

    Eijffinger, S.C.W.; Hoeberichts, M.M.

    1998-01-01

    This paper introduces a parameter for central bank independence in a monetary policy game with a conservative central banker.It tries to explain the optimal degree of central bank independence and conservativeness by four economic and political determinants, both theoretically and empirically.There appears to be a trade off between central bank independence and conservativeness.Then, by comparing the optimal degree of conservativeness and independence with the actual degree of independence, w...

  19. Colloquium on Central Asia; Colloque sur l'Asie centrale

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This colloquium on Azerbaijan was organized by the direction of international relations of the French Senate and the French center of foreign trade (CFCE). This document gathers the interventions of the participants and the debates with the audience following these interventions. The topics treated concern: - the present day political-economical situation of Central Asia countries (problem of borders, relations with Russia and China); - the economies of Central Asia countries: short term problems and medium-term perspectives; - the relations with the European Union (political, economical, trade and investments, perspectives); - the European energy stakes of Caspian sea (oil and gas reserves, development of hydrocarbon resources, exploitation and transport constraints, stakes for Europe and France); - TotalFinaElf company in Central Asia (Kazakhstan, Azerbaijan, enclavement problem); - the economical impacts of the TRACECA pathway (Transport Corridor Europe Caucasus Asia). (J.S.)

  20. Universal central extensions of direct limits of Lie superalgebras

    CERN Document Server

    Neher, Erhard

    2011-01-01

    We show that the universal central extension of a direct limit of perfect Lie superalgebras L_i is (isomorphic to) the direct limit of the universal central extensions of L_i. As an application we describe the universal central extensions of some infinite rank Lie superalgebras.

  1. On Central Series of the Multiplicative Group of Division Rings

    Institute of Scientific and Technical Information of China (English)

    Roozbeh Hazrat

    2002-01-01

    This paper studies the descending central series of the multiplicative group of a division ring. We show that certain properties, which a term in the descending central series may have, can be lifted to the full multiplicative group,and determine quotients of consecutive terms in the descending central series in tame Henselian unramified or totally ramified cases.

  2. Some properties of the central heavy ion collisions

    CERN Document Server

    Wazir, Z; Khan, E U; Haseeb, Mahnaz Q; Ajaz, M; Khan, K H

    2009-01-01

    Some experimental results are discussed in connection with the properties of the central heavy ion collisions. These experiments indicate the regime changes and saturation at some values of the centrality. This phenomenon is considered to be a signal of the percolation cluster formation in heavy ion collisions at high energies. Keywords: heavy ion collisions, theoretical models, centrality, phase transition.

  3. The Exponent Set of Central Symmetric Primitive Matrices

    Institute of Scientific and Technical Information of China (English)

    陈佘喜; 胡亚辉

    2004-01-01

    This paper first establishes a distance inequality of the associated diagraph of a central symmetric primitive matrix, then characters the exponent set of central symmetric primitive matrices, and proves that the exponent set of central symmetric primitive matrices of order n is {1, 2,… ,n-1}. There is no gap in it.

  4. The Trade Off Between Central Bank Independence and Conservativeness

    NARCIS (Netherlands)

    Eijffinger, S.C.W.; Hoeberichts, M.M.

    1996-01-01

    This paper introduces a parameter for central bank independence in a monetary policy game with a conservative central banker.It tries to explain the optimal degree of central bank independence and conservativeness by four economic and political determinants, both theoretically and empirically.There

  5. Plasticity of central chemoreceptors: effect of bilateral carotid body resection on central CO2 sensitivity.

    Directory of Open Access Journals (Sweden)

    Albert Dahan

    2007-07-01

    Full Text Available BACKGROUND: Human breathing is regulated by feedback and feed-forward control mechanisms, allowing a strict matching between metabolic needs and the uptake of oxygen in the lungs. The most important control mechanism, the metabolic ventilatory control system, is fine-tuned by two sets of chemoreceptors, the peripheral chemoreceptors in the carotid bodies (located in the bifurcation of the common carotid arteries and the central CO2 chemoreceptors in the ventral medulla. Animal data indicate that resection of the carotid bodies results, apart from the loss of the peripheral chemoreceptors, in reduced activity of the central CO2 sensors. We assessed the acute and chronic effect of carotid body resection in three humans who underwent bilateral carotid body resection (bCBR after developing carotid body tumors. METHODS AND FINDINGS: The three patients (two men, one woman were suffering from a hereditary form of carotid body tumors. They were studied prior to surgery and at regular intervals for 2-4 y following bCBR. We obtained inspired minute ventilation (Vi responses to hypoxia and CO2. The Vi-CO2 responses were separated into a peripheral (fast response and a central (slow response with a two-compartment model of the ventilatory control system. Following surgery the ventilatory CO2 sensitivity of the peripheral chemoreceptors and the hypoxic responses were not different from zero or below 10% of preoperative values. The ventilatory CO2 sensitivity of the central chemoreceptors decreased by about 75% after surgery, with peak reduction occurring between 3 and 6 mo postoperatively. This was followed by a slow return to values close to preoperative values within 2 y. During this slow return, the Vi-CO2 response shifted slowly to the right by about 8 mm Hg. CONCLUSIONS: The reduction in central Vi-CO2 sensitivity after the loss of the carotid bodies suggests that the carotid bodies exert a tonic drive or tonic facilitation on the output of the central

  6. Ecological and Tourist Potential of Central Belgrade

    Directory of Open Access Journals (Sweden)

    Nebojša Anastasijević

    2009-06-01

    Full Text Available Urban green spaces traditionally represent areas where tourists gladly pause and rest. Ecological potential of green spaces, their capacity to enhance urban life through micro-climate mitigation, and their original attractiveness, represent the source from which their tourist potential is derived. Consequently, continuous increase in plant quantity and constant expansion of their existence to green-less zones and territories, commonly defined as gray or gray-green zones, is compulsory. Green spaces of central part of old Belgrade situated on the right banks of the rivers Sava and Danube are by all criteria in the category of top tourist rank, and the same goes for this whole area with numerous attractive points within. However, this zone – the territory of three central urban municipalities (Savski Venac, Stari Grad, and Vračar – holds numerous neglected spaces, deserted corridors and backyards, river bank segments and other sites covered with weed, debris left from past and recent bombardments, parking lots and half-devastated green stripes along residential blocks. Starting with the assumption that many of these can be qualitatively renewed and professionally greenscaped, paper describes their proper development into different categories of green spaces, important structural elements of Belgrade green infrastructure.

  7. Central mechanisms II: pharmacology of brainstem pathways.

    Science.gov (United States)

    Bolser, D C

    2009-01-01

    Following systemic administration, centrally acting antitussive drugs are generally assumed to act in the brainstem to inhibit cough. However, recent work in humans has raised the possibility of suprapontine sites of action for cough suppressants. For drugs that may act in the brainstem, the specific locations, types of neurones affected, and receptor specificities of the compounds represent important issues regarding their cough-suppressant actions. Two medullary areas that have received the most attention regarding the actions of antitussive drugs are the nucleus of the tractus solitarius (NTS) and the caudal ventrolateral respiratory column. Studies that have implicated these two medullary areas have employed both microinjection and in vitro recording methods to control the location of action of the antitussive drugs. Other brainstem regions contain neurones that participate in the production of cough and could represent potential sites of action of antitussive drugs. These regions include the raphe nuclei, pontine nuclei, and rostral ventrolateral medulla. Specific receptor subtypes have been associated with the suppression of cough at central sites, including 5-HT1A, opioid (mu, kappa, and delta), GABA-B, tachykinin neurokinin-1 (NK-1) and neurokinin-2, non-opioid (NOP-1), cannabinoid, dopaminergic, and sigma receptors. Aside from tachykinin NK-1 receptors in the NTS, relatively little is known regarding the receptor specificity of putative antitussive drugs in particular brainstem regions. Our understanding of the mechanisms of action of antitussive drugs would be significantly advanced by further work in this area. PMID:18825342

  8. Badgastein spa—Austrian central Alps

    Science.gov (United States)

    Zötl, J. G.

    1995-12-01

    The Badgastein spa shows almost all the special geological and hydrological features existing in the northeastern central Alps. Situated within the Tauern window, the open joint system enables the infiltration of surface water to great depths. There it becomes heated and loaded with radon and trace elements such as fluor. The water discharges as thermal water springs at the steep right flank of the cascade of the Gastein-Ache. This hydraulic process occurs during a span of 3600 3800 years. The springs are captured in galleries, and the largest discharge is in gallery IX (2518 m3/d-1). The spa became known worldwide in the 19th century by visiting aristocrats from Central and Eastern Europe. The most important event in the 20th century was the discovery of the heat joint in the Böckstein gallery. In 1940 an effort to reactivate gold mining in the Radhausberg near Böckstein south of Badgastein failed. However, the miners had the unexpected experience of being cured of rheumatism. A connection between the great depth and high temperature in the gallery was made by the discovery of the joint set with heat and radon emanation. In the medical stations of the Böckstein gallery treatment of polyarthritis has become especially successful.

  9. Radioactivity in honey of the central Italy.

    Science.gov (United States)

    Meli, Maria Assunta; Desideri, Donatella; Roselli, Carla; Feduzi, Laura; Benedetti, Claudio

    2016-07-01

    Natural radionuclides and (137)Cs in twenty seven honeys produced in a region of the Central Italy were determined by alpha ((235)U, (238)U, (210)Po, (232)Th and (228)Th) and gamma spectrometry ((137)Cs, (40)K, (226)Ra and (228)Ra). The study was carried out in order to estimate the background levels of natural ((40)K, (238)U and (232)Th and their progeny) and artificial radionuclides ((137)Cs) in various honey samples, as well as to compile a data base for radioactivity levels in that region. (40)K showed a mean activity of 28.1±23.0Bqkg(-1) with a range of 7.28-101Bqkg(-1). The mean of (210)Po activity resulted 0.40±0.46Bqkg(-1) with a range of 0.03-1.98Bqkg(-1). The mean of (238)U activity resulted 0.020±0.010Bqkg(-1). (226)Ra and (228)Ra resulted always natural radiation exposure in Italy. The honeys produced in Central Italy were of good quality in relation to the studied parameters, confirming the general image of a genuine and healthy food associated to this traditional products. PMID:26920304

  10. Central Sleep Apnea at High Altitude.

    Science.gov (United States)

    Burgess, Keith R; Ainslie, Philip N

    2016-01-01

    The discovery of central sleep apnea (CSA) at high altitude is usually attributed to Angelo Mosso who published in 1898. It can occur in susceptible individuals at altitude above 2000 m, but at very high altitude, say above 5000 m, it will occur in most subjects. Severity is correlated with ventilatory responsiveness, particularly to hypoxia. Theoretically, it should spontaneously improve with time and acclimatization. Although the time course of resolution is not well described, it appears to persist for more than a month at 5000 m.It occurs due to the interaction of hypocapnia with stages 1 and 2 NREM sleep, in the presence of increased loop-gain. The hypocapnia is secondary to hypoxic ventilatory drive. With acclimatization, one might expect that the increase in PaO2 and cerebral blood flow (CBF) would mitigate the CSA. However, over time, both the hypoxic and hypercapnic ventilatory responses increase, causing an increase in loop gain which is a counteracting force.The severity of the CSA can be reduced by descent, supplemental oxygen therapy, oral or intravenous acetazolamide. Recent studies suggest that acute further increases in cerebral blood flow will substantially, but temporarily, reduce central sleep apnea, without altering acid based balance. Very recently, bi-level noninvasive ventilation has also been shown to help (mechanism unknown). Sleep quality can be improved independent of the presence of CSA by the use of benzodiazepine sedation. PMID:27343103

  11. Central Safety Department. Annual report 1986

    International Nuclear Information System (INIS)

    The Safety Officer and the Security Officer are responsible for radiation protection and technical safety, both conventional and nuclear, for the physical protection as well as the safeguards of nuclear materials and radioactive substances within the Kernforschungszentrum Karlsruhe GmbH (KfK). To fulfill these functions they rely on the assistance of the Central Safety Department. The Central Safety Department is responsible for handling all problems of radiation protection, safety and security of the institutes and departments of the Karlsruhe Nuclear Research Center, for waste water activity measurements and environmental monitoring of the whole area of the Center, and for research and development work mainly focusing on nuclear safety and radiation protection measures. The r+d work concentrates on the following aspects: physical and chemical behavior of biologically particularly active radionuclides, behavior of HT in the air/plant/soil system, biophysics of multicellular systems, improvement in radiation protection measurement and personnel dosimetry. The report gives details of the different duties, indicates the results of 1986 routine tasks and reports about results of investigations and developments of the working groups of the Department. (orig.)

  12. Reading performance and central field loss.

    Science.gov (United States)

    Kanonidou, E

    2011-04-01

    Age-related macular degeneration is a major cause of blindness in Europe and the U.S. and a leading cause of significant loss of visual acuity in elderly patients. Reading is a key visual task in everyday living involving a synthesis of a number of different motor, sensory and cognitive functions. When the centre of a reader's visual field is obscured, reading speed declines and oculomotor pattern differs, compared to normal reading. Improvement in the generation of visual stimuli using computer-generated images and projection/display systems as well as advances in eye movement recording techniques, including infrared pupil tracking and magnetic search coils, have contributed greatly to our understanding of these sensorimotor abnormalities. The developed reading strategies have been thoroughly investigated in individuals with central field loss either induced artificially or related to eye pathology.The following review aims at presenting the contemporary literature regarding the sensory and oculomotor deficits in reading ability, resulting from central field loss and should contribute to a greater understanding of the functional visual deficit caused by this visual impairment.

  13. Randomized central limit theorems: A unified theory

    Science.gov (United States)

    Eliazar, Iddo; Klafter, Joseph

    2010-08-01

    The central limit theorems (CLTs) characterize the macroscopic statistical behavior of large ensembles of independent and identically distributed random variables. The CLTs assert that the universal probability laws governing ensembles’ aggregate statistics are either Gaussian or Lévy, and that the universal probability laws governing ensembles’ extreme statistics are Fréchet, Weibull, or Gumbel. The scaling schemes underlying the CLTs are deterministic—scaling all ensemble components by a common deterministic scale. However, there are “random environment” settings in which the underlying scaling schemes are stochastic—scaling the ensemble components by different random scales. Examples of such settings include Holtsmark’s law for gravitational fields and the Stretched Exponential law for relaxation times. In this paper we establish a unified theory of randomized central limit theorems (RCLTs)—in which the deterministic CLT scaling schemes are replaced with stochastic scaling schemes—and present “randomized counterparts” to the classic CLTs. The RCLT scaling schemes are shown to be governed by Poisson processes with power-law statistics, and the RCLTs are shown to universally yield the Lévy, Fréchet, and Weibull probability laws.

  14. Solar central receiver heliostat reflector assembly

    Science.gov (United States)

    Horton, Richard H.; Zdeb, John J.

    1980-01-01

    A heliostat reflector assembly for a solar central receiver system comprises a light-weight, readily assemblable frame which supports a sheet of stretchable reflective material and includes mechanism for selectively applying tension to and positioning the sheet to stretch it to optical flatness. The frame is mounted on and supported by a pipe pedestal assembly that, in turn, is installed in the ground. The frame is controllably driven in a predetermined way by a light-weight drive system so as to be angularly adjustable in both elevation and azimuth to track the sun and efficiently continuously reflect the sun's rays to a focal zone, i.e. central receiver, which forms part of a solar energy utilization system, such as a solar energy fueled electrical power generation system. The frame may include a built-in system for testing for optical flatness of the reflector. The preferable geometric configuration of the reflector is octagonal; however, it may be other shapes, such as hexagonal, pentagonal or square. Several different embodiments of means for tensioning and positioning the reflector to achieve optical flatness are disclosed. The reflector assembly is based on the stretch frame concept which provides an extremely light-weight, simple, low-cost reflector assembly that may be driven for positioning and tracking by a light-weight, inexpensive drive system.

  15. Parallelization of game theoretic centrality algorithms

    Indian Academy of Sciences (India)

    M Vishnu Sankar; Balaraman Ravindran

    2015-09-01

    Communication has become a lot easier with the advent of easy and cheap means of reaching people across the globe. This has allowed the development of large networked communities and, with the technology available to track them, has opened up the study of social networks at unprecedented scales. This has necessitated the scaling up of various network analysis algorithms that have been proposed earlier in the literature. While some algorithms can be readily adapted to large networks, in many cases the adaptation is not trivial. In this work, we explore the scaling up of a class of node centrality algorithms based on cooperative game theory. These were proposed earlier as an efficient alternatives to traditional measure of information diffusion centrality.We present here distributed versions of these algorithms in a Map-Reduce framework, currently the most popular distributed computing paradigm. We empirically demonstrate the scaling behavior of our algorithm on very large synthetic networks thereby establishing the utility of these methods in settings such as online social networks.

  16. Central centrifugal cicatricial alopecia: challenges and solutions.

    Science.gov (United States)

    Herskovitz, Ingrid; Miteva, Mariya

    2016-01-01

    Central centrifugal cicatricial alopecia (CCCA) is the most common scarring alopecia among African American women. Data about epidemiology, etiology, genetic inheritance, and management are scarce and come from individual reports or small series. CCCA has been associated with hot combing and traumatic hair styling for years; however, studies fail to confirm it as the sole etiologic factor. It has been shown in a small series that CCCA can be inherited in an autosomal dominant fashion, with a partial penetrance and a strong modifying effect of hairstyling and sex. CCCA presents clinically as a central area of progressive irreversible hair loss that expands to the periphery. A patchy form has also been described. Dermoscopy is helpful to identify the optimal site for the biopsy, which establishes the diagnosis. Well-designed randomized controlled trials are needed to discover the optimal management. At this point, patients are advised to avoid traction and chemical treatments; topical and intralesional steroids, calcineurin inhibitors, and minoxidil can be helpful in halting the progression. PMID:27574457

  17. First Operation of the Central Solenoid

    CERN Multimedia

    Ruber, R.

    2006-01-01

    A new phase for the ATLAS collaboration started with the first operation of a completed sub-system: the Central Solenoid. It was cooled down from the 17th to 23th May 2006, and the first kA was put into it the same evening as it was cold and superconductive. That makes our solenoid the very first cold and superconducting magnet to be operated in the LHC underground areas. The Central Solenoid in its final position at the heart of ATLAS. The coil current (red line) and voltage (blue line) showing the operation at nominal current of 7.73 kA for a magnetic field of 2.0 T and the subsequent successful commissioning up to 8 kAT The cool down and powering of the solenoid was a major milestone for all control, cryogenic, power and vacuum systems and was achieved in perfect collaboration with the liquid argon detector with which it shares the Barrel Cryostat. Powering up to nominal current had to wait until the last week of July when the End-Cap Calorimeters were in closed position. The Tile Barrel and E...

  18. Central cholinergic regulation of respiration: nicotinic receptors

    Institute of Scientific and Technical Information of China (English)

    Xuesi M SHAO; Jack L FELDMAN

    2009-01-01

    Nicotinic acetylcholine receptors (nAChRs) are expressed in brainstem and spinal cord regions involved in the control of breathing. These receptors mediate central cholinergic regulation of respiration and effects of the exogenous ligand nicotine on respiratory pattern. Activation of a4* nAChRs in the preBotzinger Complex (preBotC), an essential site for normal respiratory rhythm generation in mammals, modulates excitatory glutamatergic neurotransmission and depolarizes preBotC inspiratory neurons, leading to increases in respiratory frequency. nAChRs are also present in motor nuclei innervating respiratory muscles. Activation of post- and/or extra-synaptic a4* nAChRs on hypoglossal (XII) motoneurons depolarizes these neurons, potentiating tonic and respiratory-related rhythmic activity. As perinatal nicotine exposure may contribute to the pathogenesis of sudden infant death syndrome (SIDS), we discuss the effects of perinatal nicotine exposure on development of the cholinergic and other neurotransmitter systems involved in control of breathing. Advances in understanding of the mechanisms underlying central cholinergic/nicotinic modulation of respiration provide a pharmacological basis for exploiting nAChRs as therapeutic targets for neurological disorders related to neural control of breathing such as sleep apnea and SIDS.

  19. [Parasitic diseases of the central nervous system].

    Science.gov (United States)

    Schmutzhard, E

    2010-02-01

    Central nervous system infections and infestations by protozoa and helminths constitute a problem of increasing importance throughout all of central European and northern/western countries. This is partially due to the globalisation of our society, tourists and business people being more frequently exposed to parasitic infection/infestation in tropical countries than in moderate climate countries. On top of that, migrants may import chronic infestations and infections with parasitic pathogens, eventually also--sometimes exclusively--involving the nervous system. Knowledge of epidemiology, initial clinical signs and symptoms, diagnostic procedures as well as specific chemotherapeutic therapies and adjunctive therapeutic strategies is of utmost important in all of these infections and infestations of the nervous systems, be it by protozoa or helminths. This review lists, mainly in the form of tables, all possible infections and infestations of the nervous systems by protozoa and by helminths. Besides differentiating parasitic diseases of the nervous system seen in migrants, tourists etc., it is very important to have in mind that disease-related (e.g. HIV) or iatrogenic immunosuppression has led to the increased occurrence of a wide variety of parasitic infections and infestations of the nervous system (e. g. babesiosis, Chagas disease, Strongyloides stercoralis infestation, toxoplasmosis, etc.). PMID:20111855

  20. Central extension of graded Lie algebras

    CERN Document Server

    Welte, Angelika

    2010-01-01

    In this thesis we describe the universal central extension of two important classes of so-called root-graded Lie algebras defined over a commutative associative unital ring $k.$ Root-graded Lie algebras are Lie algebras which are graded by the root lattice of a locally finite root system and contain enough $\\mathfrak{sl}_2$-triples to separate the homogeneous spaces of the grading. Examples include the infinite rank analogs of the simple finite-dimensional complex Lie algebras. \\\\ In the thesis we show that in general the universal central extension of a root-graded Lie algebra $L$ is not root-graded anymore, but that we can measure quite easily how far it is away from being so, using the notion of degenerate sums, introduced by van der Kallen. We then concentrate on root-graded Lie algebras which are graded by the root systems of type $A$ with rank at least 2 and of type $C$. For them one can use the theory of Jordan algebras.

  1. Metabolic syndrome and central retinal artery occlusion

    Directory of Open Access Journals (Sweden)

    Kosanović-Jaković Natalija

    2005-01-01

    Full Text Available Background. The accumulation of risk factors for central retinal artery occlusion can be seen in a single person and might be explained by the metabolic syndrome. Case report. We presented the case of a 52-year-old man with no light perception in his right eye. The visual loss was monocular and painless, fundoscopy showed central retinal artery occlusion and the laboratory investigation showed the raised erythrocyte sedimentation rate of 105 mm/h and the raised C-reactive protein of 22 mg/l. Specific laboratory investigations and fluorescein angiography excluded the presence of vasculitis, collagen vascular diseases, hypercoagulable state and antiphospholipid syndrome. Conclusion. The patient met all the five of the National Cholesterol Education Program (NCEP criteria for the metabolic syndrome: hypertension, abnormal lipid profile, abnormal glucose metabolism, obesity and hyperuricemia. Measurement of C-reactive protein is useful for the assessment of therapeutic systemic effect on any abnormality in the metabolic syndrome. Individual therapy for all risk factors in the metabolic syndrome is necessary to prevent complications such as cardiovascular, retinal vascular diseases and stroke.

  2. Optimization of ITER Central Solenoid Insert design

    Energy Technology Data Exchange (ETDEWEB)

    Khodak, Andrei, E-mail: akhodak@pppl.gov [Princeton Plasma Physics Laboratory, Princeton, NJ 08543 (United States); Martovetsky, Nicolai; Smirnov, Alexandre [Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); Titus, Peter [Princeton Plasma Physics Laboratory, Princeton, NJ 08543 (United States)

    2013-10-15

    Highlights: ► Modifications of coil design for testing ITER superconducting cable are presented. ► Numerical analysis allowed optimal selection of the material for the coil spacers. ► Current sharing temperature distributions along the cable are predicted. -- Abstract: The United States ITER Project Office (USIPO) is responsible for fabrication of the Central Solenoid (CS) for International Thermonuclear Experimental Reactor (ITER). The CS Insert (CSI) project should provide a verification of the conductor performance in relevant conditions of temperature, field, currents and mechanical strain. The US IPO will build the CSI that will be tested at the Central Solenoid Model Coil (CSMC) Test Facility at JAEA, Naka. One of the design goals of the CSI is to assure that the properties of the conductor near the median plane are measured accurately. Since Nb3Sn is strain sensitive and electromagnetic forces generate a significant strain that increases the current sharing temperature (T{sub cs}), we need to design the Insert in such a way that the most strained conductor near the median plane would still have the lowest T{sub cs} of all the rest of the conductor in the Insert. The difference between thermal contraction of the jacket and spacer material allows controlling axial distribution of the coil radial deformation. Numerical analysis of the CSI was performed using stainless steel, titanium and invar spacer material variants. Distribution of the T{sub cs} was obtained from numerical results in the form similar to one proposed for ITER.

  3. Metastatic neoplasms of the central nervous system

    International Nuclear Information System (INIS)

    Metastatic neoplasms to the central nervous system are often encountered in the practice of surgical neuropathology. It is not uncommon for patients with systemic malignancies to present to medical attention because of symptoms from a brain metastasis and for the tissue samples procured from these lesions to represent the first tissue available to study a malignancy from an unknown primary. In general surgical pathology, the evaluation of a metastatic neoplasm of unknown primary is a very complicated process, requiring knowledge of numerous different tumor types, reagents, and staining patterns. The past few years, however, have seen a remarkable refinement in the immunohistochemical tools at our disposal that now empower neuropathologists to take an active role in defining the relatively limited subset of neoplasms that commonly metastasize to the central nervous system. This information can direct imaging studies to find the primary tumor in a patient with an unknown primary, clarify the likely primary site of origin in patients who have small tumors in multiple sites without an obvious primary lesion, or establish lesions as late metastases of remote malignancies. Furthermore, specific treatments can begin and additional invasive procedures may be prevented if the neuropathologic evaluation of metastatic neoplasms provides information beyond the traditional diagnosis of ''metastatic neoplasm.'' In this review, differential cytokeratins, adjuvant markers, and organ-specific antibodies are described and the immunohistochemical signatures of metastatic neoplasms that are commonly seen by neuropathologists are discussed

  4. Central Equatorial Pacific Experiment (CEPEX). Design document

    Energy Technology Data Exchange (ETDEWEB)

    1993-04-01

    The Earth`s climate has varied significantly in the past, yet climate records reveal that in the tropics, sea surface temperatures seem to have been remarkably stable, varying by less than a few degrees Celsius over geologic time. Today, the large warm pool of the western Pacific shows similar characteristics. Its surface temperature always exceeds 27{degree}C, but never 31{degree}C. Heightened interest in this observation has been stimulated by questions of global climate change and the exploration of stabilizing climate feedback processes. Efforts to understand the observed weak sensitivity of tropical sea surface temperatures to climate forcing has led to a number of competing ideas about the nature of this apparent thermostat. Although there remains disagreement on the processes that regulate tropical sea surface temperature, most agree that further progress in resolving these differences requires comprehensive field observations of three-dimensional water vapor concentrations, solar and infrared radiative fluxes, surface fluxes of heat and water vapor, and cloud microphysical properties. This document describes the Central Equatorial Pacific Experiment (CEPEX) plan to collect such observations over the central equatorial Pacific Ocean during March of 1993.

  5. From printing to Scielo and Pubmed Central

    Directory of Open Access Journals (Sweden)

    Luis Eduardo Bravo

    2014-04-01

    Full Text Available The first issue of Philosophical Transactions from the Royal Society published in 1665 is widely regarded as the beginning of modern academic communication through journal articles. This form of presentation was an alternative to books for facilitating the exchange of ideas among scholarly circles. Soon journal collections and scientific libraries were created and eventually an evaluation of the quality of research activity was sought through noting the impact of their publications1. With guidance from the National University of Colombia and support from Scielo Brazil, in 2013 the standards of the US-NLM were implemented and technical endorsement by Pubmed Central was attained.  Colombia Médica´s retention over time is guaranteed by the US-NLM; as of 2014 it will become part of PubMed Central, the free digital archive of biomedical and biological sciences of the U.S. National Institute of Health, which is considered to be the most important digital library in the world. The guidance of the journals by multidisciplinary teams, the policy of free access to its contents, and the technological transfer with the use of free software will help the journals of middle and low-income countries to overcome barriers to diffusion and to maintain technological independence from commercial publishers. Colombia Médica makes an impassioned plea to WHO/PAHO to support BIREME, Brazil and convert SciELO into a certified digital repository.

  6. Central auditory masking by an illusory tone.

    Directory of Open Access Journals (Sweden)

    Christopher J Plack

    Full Text Available Many natural sounds fluctuate over time. The detectability of sounds in a sequence can be reduced by prior stimulation in a process known as forward masking. Forward masking is thought to reflect neural adaptation or neural persistence in the auditory nervous system, but it has been unclear where in the auditory pathway this processing occurs. To address this issue, the present study used a "Huggins pitch" stimulus, the perceptual effects of which depend on central auditory processing. Huggins pitch is an illusory tonal sensation produced when the same noise is presented to the two ears except for a narrow frequency band that is different (decorrelated between the ears. The pitch sensation depends on the combination of the inputs to the two ears, a process that first occurs at the level of the superior olivary complex in the brainstem. Here it is shown that a Huggins pitch stimulus produces more forward masking in the frequency region of the decorrelation than a noise stimulus identical to the Huggins-pitch stimulus except with perfect correlation between the ears. This stimulus has a peripheral neural representation that is identical to that of the Huggins-pitch stimulus. The results show that processing in, or central to, the superior olivary complex can contribute to forward masking in human listeners.

  7. The impact of centrality on cooperative processes

    CERN Document Server

    Reia, Sandro M; Fontanari, José F

    2016-01-01

    The solution of today's complex problems requires the grouping of task forces whose members are usually connected remotely over long physical distances and different time zones, so the importance of understanding the effects of imposed communication patterns (i.e., who can communicate with whom) on group performance. Here we use an agent-based model to explore the influence of the betweenness centrality of the nodes on the time the group requires to find the global maxima of families of NK-fitness landscapes. The agents cooperate by broadcasting messages informing on their fitness to their neighbors and use this information to copy the more successful agent in their neighborhood. We find that for easy tasks (smooth landscapes) the topology of the communication network has no effect on the performance of the group and that the more central nodes are the most likely to find the global maximum first. For difficult tasks (rugged landscapes), however, we find a positive correlation between the variance of the betw...

  8. Central Solenoid On-surface Test

    CERN Multimedia

    Ruber, R

    2004-01-01

    A full scale on-surface test of the central solenoid has been performed before its final installation in the ATLAS cavern starting in November. The successful integration of the central solenoid into the barrel cryostat, as reported in the March 2004 ATLAS eNews, was hardly finished when testing started. After a six-week period to cool down the LAr calorimeter, the solenoid underwent a similar procedure. Cooling it down to 4.6 Kelvin from room temperature took just over five and a half days. Cold and superconducting, it was time to validate the functionality of the control and safety systems. These systems were largely the same as the systems to be used in the final underground installation, and will be used not only for the solenoid and toroid magnets, but parts of it also for other LHC experiments. This solenoid test was the first occasion to test the system functionality in a real working environment. Several days were spent to fine tune the systems, especially the critical safety system, which turned out...

  9. North Central Project: Environment act proposal

    International Nuclear Information System (INIS)

    Manitoba Hydro proposes to construct a power transmission and distribution line system to connect 12 northern Manitoba communities to the utility's central power grid. The purpose of this North Central Project (NCP) is to provide reliable and unrestricted electric service to remote communities now largely receiving limited diesel-generated power. The NCP is composed of a 138-kV transmission line running ca 350 km from the Kelsey Generating Station, ca 160 km of 25-kV distribution lines, new transformer stations at four communities, upgraded internal distribution systems within the communities, removal of existing diesel stations and restoration of the sites, modifications and additions to the Kelsey switchyard, and a communications system. The NCP is described in detail, including proposed line routes and transformer station locations, rationales for site and route selection, projected impacts on the environment and local societies, and consultations with the communities to be affected. Potential impacts are expected to be modest, with few unmitigable adverse impacts and a number of potentially significant positive benefits. Impact management measures are proposed to prevent or mitigate adverse effects and to create or enhance positive impacts such as local employment of native peoples. 49 figs., 1 tab

  10. Central centrifugal cicatricial alopecia: challenges and solutions.

    Science.gov (United States)

    Herskovitz, Ingrid; Miteva, Mariya

    2016-01-01

    Central centrifugal cicatricial alopecia (CCCA) is the most common scarring alopecia among African American women. Data about epidemiology, etiology, genetic inheritance, and management are scarce and come from individual reports or small series. CCCA has been associated with hot combing and traumatic hair styling for years; however, studies fail to confirm it as the sole etiologic factor. It has been shown in a small series that CCCA can be inherited in an autosomal dominant fashion, with a partial penetrance and a strong modifying effect of hairstyling and sex. CCCA presents clinically as a central area of progressive irreversible hair loss that expands to the periphery. A patchy form has also been described. Dermoscopy is helpful to identify the optimal site for the biopsy, which establishes the diagnosis. Well-designed randomized controlled trials are needed to discover the optimal management. At this point, patients are advised to avoid traction and chemical treatments; topical and intralesional steroids, calcineurin inhibitors, and minoxidil can be helpful in halting the progression.

  11. Central centrifugal cicatricial alopecia: challenges and solutions

    Directory of Open Access Journals (Sweden)

    Herskovitz I

    2016-08-01

    Full Text Available Ingrid Herskovitz, Mariya Miteva Department of Dermatology and Cutaneous Surgery, University of Miami L Miller School of Medicine, Miami, FL, USA Abstract: Central centrifugal cicatricial alopecia (CCCA is the most common scarring alopecia among African American women. Data about epidemiology, etiology, genetic inheritance, and management are scarce and come from individual reports or small series. CCCA has been associated with hot combing and traumatic hair styling for years; however, studies fail to confirm it as the sole etiologic factor. It has been shown in a small series that CCCA can be inherited in an autosomal dominant fashion, with a partial penetrance and a strong modifying effect of hairstyling and sex. CCCA presents clinically as a central area of progressive irreversible hair loss that expands to the periphery. A patchy form has also been described. Dermoscopy is helpful to identify the optimal site for the biopsy, which establishes the diagnosis. Well-designed randomized controlled trials are needed to discover the optimal management. At this point, patients are advised to avoid traction and chemical treatments; topical and intralesional steroids, calcineurin inhibitors, and minoxidil can be helpful in halting the progression. Keywords: hair loss, alopecia, dermatoscopy, dermoscopy, trichoscopy, black scalp, African American, scarring alopecia

  12. UPGRADE OF THE CENTRAL WEB SERVERS

    CERN Multimedia

    WEB Services

    2000-01-01

    During the weekend of the 25-26 March, the infrastructure of the CERN central web servers will undergo a major upgrade.As a result, the web services hosted by the central servers (that is, the services the address of which starts with www.cern.ch) will be unavailable Friday 24th, from 17:30 to 18:30, and may suffer from short interruptions until 20:00. This includes access to the CERN top-level page as well as the services referenced by this page (such as access to the scientific program and events information, or training, recruitment, housing services).After the upgrade, the change will be transparent to the users. Expert readers may however notice that when they connect to a web page starting with www.cern.ch this address is slightly changed when the page is actually displayed on their screen (e.g. www.cern.ch/Press will be changed to Press.web.cern.ch/Press). They should not worry: this behaviour, necessary for technical reasons, is normal.web.services@cern.chTel 74989

  13. Uranium Mill Tailings Remediation in Central Asia

    International Nuclear Information System (INIS)

    Uranium ore is a naturally occurring radioactive material which is often regarded as something separate to NORM due to its place at the front end of the nuclear fuel cycle. Uranium mining and processing was a significant industry in the Central Asian countries of the former Soviet Union. When the Soviet Union broke up in 1989 these countries gained their independence but the uranium mining industry now had to try and survive in a new economic environment. In Tajikistan and Kyrgyzstan this proved too great a challenge. Production stopped and sites were simply abandoned with little or no attention paid to remediation. Skilled personnel departed and both physical and regulatory infrastructure decayed. Consequently, the legacies of the former times remained throughout Central Asia to become an issue of considerable concern to many. The sites were generally uncontrolled and the NORM residues from the mining and processing were a source of environmental contamination which also threatened public health in a number of ways. In recent years there has been considerable activity by a number of international agencies and Governments working towards solutions for these issues. Much of the effort has been undertaken by the IAEA and this paper describes the original situation, the development of remediation strategies and the various remediation related projects, their outcomes to date, and plans for the future in both the political and scientific arenas. (author)

  14. Dynamics of the Central American Pacific

    Science.gov (United States)

    Vieytez, Begonia; Marrero-Díaz, Ángeles; José Machín, Francisco; José Gavidia, Francisco; Castro, Mi

    2014-05-01

    The Central American Pacific (CAP) is the area located in front of the Central America coast, within the Eastern Tropical Pacific region (ETP). The CAP dynamic is strongly influenced by the NE and SE trade winds, also this area is characterized by the presence of coastal wind jets at Gulf of Papagayo and Gulf of Panama, which are product of wind pulses blowing through the mountain gaps of the central cordillera, generating important eddies as the cyclonic eddy of Costa Rica Dome (CRD). Nevertheless, the implications of the topography of the continental margin of Central America in the determination of the dynamic processes in the area related to the action of winds and currents are still unknown. Between November and December 2010 (dry season), onboard the R/V Miguel Oliver, oceanographic parameters were measured in the CAP area, which despite its importance, has been poorly investigated until date. Available oceanographic information was processed in order to describe the dynamic along the Pacific coast of Central America, which is notable for its particularly strong stratification in the water column and the distribution of properties, as response to the presence of areas with high temperatures (above 28° C) and other areas with salinity minimum (less than 24). In this study was possible to distinguish three hydrographic zones: PM, south, in the adjacent region to Gulf of Panama, PY, in the center, in the adjacent region to Gulf of Papagayo, and FC, to the north, in the adjacent region to Gulf of Fonseca. The surface transformations of the water bodies, from south to north, observed in these zones could be indicting the presence of Costa Rica current. The prevailing wind system is the main force of variations in the surface distribution of the temperature in the area, and they are responsible of important structures as the anticyclonic eddy in front Gulf of Fonseca, eddies derived from the wind pulses of Gulf of Papagayo, and the relatively low temperatures in

  15. The Influence of Soft Contact Lens Materials on the Central, Para-Central and Peripheral Corneal Endothelium

    OpenAIRE

    Lloyd McKernan, Aoife; Simo Mannion, Luisa; O'Dwyer, Veronica

    2015-01-01

    Title: The influence of soft contact lens materials on the central, para-central and peripheral corneal endothelium prior to and following two weeks cessation of soft contact lens wear. Purpose: To examine the influence of a variety of soft contact lens (SCL) materials on the central, para-central and peripheral corneal endothelium measurements, prior to and following two weeks cessation of SCL wear. Methods: Endothelial measurements were taken using the CEM-530 (Nidek, Japan) specular ...

  16. The Olig family affects central nervous system development and disease

    Institute of Scientific and Technical Information of China (English)

    Botao Tan; Jing Yu; Ying Yin; Gongwei Jia; Wei Jiang; Lehua Yu

    2014-01-01

    Neural cell differentiation and maturation is a critical step during central nervous system devel-opment. The oligodendrocyte transcription family (Olig family) is known to be an important factor in regulating neural cell differentiation. Because of this, the Olig family also affects acute and chronic central nervous system diseases, including brain injury, multiple sclerosis, and even gliomas. Improved understanding about the functions of the Olig family in central nervous system development and disease will greatly aid novel breakthroughs in central nervous system diseases. This review investigates the role of the Olig family in central nervous system develop-ment and related diseases.

  17. Community Resources Guide for Central Florida = Una Guia de Recursos en la Comunidad de Florida Central.

    Science.gov (United States)

    Medina, Linda, Comp.

    Designed to orient Hispanic refugees to the services that are available in Central Florida, this bilingual guide consists of a section of general information on living and working in the United States and a section devoted to various public and private agencies. Provided first are addresses and phone numbers of various government agencies:…

  18. Central nervous control of energy and glucose balance: Focus on the central melanocortin system

    Science.gov (United States)

    Studies have suggested that manipulations of the central melanocortin circuitry by pharmacological agents produce robust effects on the regulation of body weight and glucose homeostasis. In this review, we discuss recent findings from genetic mouse models that have further established the physiologi...

  19. Rural communities in the Central African context : the Nkoya of Central Western Zambia

    NARCIS (Netherlands)

    Binsbergen, W.M.J.

    1983-01-01

    Nkoya is an ethnic and linguistic label applying to about 50,000 people inhabiting the wooded plateau of Central Western Zambia. The author discusses the valley as the effective rural community and the villages as the main constituent social units within the valley and finally indicates the place of

  20. Implementation of harm reduction in Central and Eastern Europe and Central Asia.

    Science.gov (United States)

    Sarang, Anya; Stuikyte, Raminta; Bykov, Roman

    2007-03-01

    Harm reduction (HR) interventions began in Central-Eastern Europe and Central Asia in the mid-1980s with the establishment of substitution treatment (ST) in Yugoslavia. In the mid-1990s, the first needle and syringe programmes (NSPs) opened in selected countries following the outbreaks of HIV among injecting drug users (IDUs). The number of NSPs continues to increase via a combination of international and state funding with large expansions made possible via the Global Fund to Fight AIDS, Tuberculosis and Malaria. While ST is still unaccepted in several countries, others have made some progress which is especially visible in South Eastern and Central Europe and the Baltic States. Development of regional networking including Central and Eastern European HR Network and a number of national networks helped to coordinate joint advocacy effort and in some cases sustain HR services. Activism of drug users and people living with HIV (PLWH) increased in the region in the last several years and helped to better link HR with the affected communities. Still a number of challenges remain important for the movement today such as repressive drug policies; stigma and discrimination of IDUs, PLWH, sex workers and inmates, including poor access to prevention and treatment; lack of important components of HR work such as naloxone distribution and hepatitis B vaccination, prevention in prisons; issues of quality control; sustaining services after finishing of major international projects; reaching of adequate coverage and others.

  1. Ethnobotanical remarks on Central and Southern Italy

    Directory of Open Access Journals (Sweden)

    Lucia Leporatti

    2007-05-01

    Full Text Available Abstract Background The present paper is a brief survey on the ethnobotanical works published by the Authors since 1981, concerning the research carried out in some southern and central Italian regions. Before Roman domination these territories were first inhabited by local people, while the southern areas were colonized by the Greeks. These different cultural contributions left certain traces, both in the toponyms and in the vernacular names of the plants and, more generally, in the culture as a whole. Methods Field data were collected through open interviews, mainly of farmers, shepherds and elderly people, born or living in these areas for a long time. Voucher specimens of collected plants are preserved in the respective herbaria of the Authors and in the herbarium of "Roma Tre" University. Important contributions have been made by several students native to the areas under consideration. A comparative analysis with local specific ethnobotanical literature was carried out. Results The paper reports several examples concerning human and veterinary popular medicine and in addition some anti-parasitic, nutraceutic, dye and miscellaneous uses are also described. Moreover vernacular names and toponyms are cited. Eight regions of central and southern Italy (particularly Latium, Abruzzo, Marche and Basilicata were investigated and the data obtained are presented in 32 papers. Most of the species of ethnobotanical interest have been listed in Latium (368 species, Marche (274 and Abruzzo (203. The paper also highlights particularly interesting aspects or uses not previously described in the specific ethnobotanical literature. Conclusion Phyto-therapy in central and southern Italy is nowadays practised by a few elderly people who resort to medicinal plants only for mild complaints (on the contrary food uses are still commonly practised. Nowadays therapeutic uses, unlike in the past, are less closely or not at all linked to ritual aspects. Several

  2. Central airways remodeling in COPD patients

    Directory of Open Access Journals (Sweden)

    Pini L

    2014-09-01

    Full Text Available Laura Pini,1 Valentina Pinelli,2 Denise Modina,1 Michela Bezzi,3 Laura Tiberio,4 Claudio Tantucci1 1Unit of Respiratory Medicine, Department of Clinical and Experimental Sciences, University of Brescia, 2Department of Respiratory Medicine, Spedali Civili di Brescia, 3Department Bronchoscopy, Spedali Civili di Brescia, 4Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy Background: The contribution to airflow obstruction by the remodeling of the peripheral airways in chronic obstructive pulmonary disease (COPD patients has been well documented, but less is known about the role played by the large airways. Few studies have investigated the presence of histopathological changes due to remodeling in the large airways of COPD patients. Objectives: The aim of this study was to verify the presence of airway remodeling in the central airways of COPD patients, quantifying the airway smooth muscle (ASM area and the extracellular matrix (ECM protein deposition, both in the subepithelial region and in the ASM, and to verify the possible contribution to airflow obstruction by the above mentioned histopathological changes. Methods: Biopsies of segmental bronchi spurs were performed in COPD patients and control smoker subjects and immunostained for collagen type I, versican, decorin, biglycan, and alpha-smooth muscle actin. ECM protein deposition was measured at both subepithelial, and ASM layers. Results: The staining for collagen I and versican was greater in the subepithelial layer of COPD patients than in control subjects. An inverse correlation was found between collagen I in the subepithelial layer and both forced expiratory volume in 1 second and ratio between forced expiratory volume in 1 second and forced vital capacity. A statistically significant increase of the ASM area was observed in the central airways of COPD patients versus controls. Conclusion: These findings indicate that airway remodeling also affects

  3. A Central Brazil GT5 Event

    Science.gov (United States)

    Barros, L. V.; Assumpcao, M.; Caixeta, D.

    2013-05-01

    Ground-truth (GT) events, accurately located with a precision of 5 km (GT5 event) and associated travel times to regional stations are important in developing precise velocity models. The low Brazilian seismicity, with only three continental earthquakes of magnitude five in the last three decades, and the low number of seismic stations explain the difficulty to detect events at regional distances. In the world maps of GT events, Brazil appears almost empty. In Stable Continental Interiors, like Brazil, it is difficult to find an event fulfilling all the GT5 prerequisites, particularly in respect with the number of picked phases and azimuthal gaps. Recently PTS-CTBTO has organized meeting and workshops to encourage seismologists from South and Central America to cooperate with the work of identifying GT5 events in these countries, with a goal of developing a 3-dimentional velocity model for this part of the globe not covered yet like Europe and North America. As a result we studied a recent magnitude 5 event in Central Brazil detected by few regional stations. Aftershock studies with local stations, showed a fault 5 km long. Taking the mainshock epicenter as the center of fault the maximum error would be minimal, 2.5 km, assuming the events were located with zero uncertainty. The parameters depth and origin time source were precisely determined using correlations between waveforms of six events and stations corrections. The event magnitudes range from 3.5 to 5.0 (mainshock, taken as reference event) recorded by regional and local stations. Events recorded at local and regional stations were used to determine the regional station corrections. These events were located only with data from local stations, assigning to the regional stations P and S phases zero weight in order to determine residuals for each regional stations used. The stations corrections were taken as the average of the residuals at each station. Precise pickings of P and S phases for the mainshock

  4. Conservation et anthropisation en Afrique centrale

    Directory of Open Access Journals (Sweden)

    Vermeulen, C.

    2015-01-01

    Full Text Available Conservation and Anthropization in Central Africa. As we enter a millennium often referred to as Anthropocene, with reference to the influence never before seen in the history of a species namely the human being, world biodiversity declines at an accelerated pace. A pace of change so severe that researchers have difficulties describing the current phenomena. Wildlife in particular is seriously threatened, to such an extent that we speak about the biggest massive extinction of animal species ever to occur on Earth. Many regions of the globe, in particular Central Africa, thus see theirbiodiversity disappearing before it is even documented. With regard to its concerns about the sustainability of the environment, the journal Tropicultura now opens its columns to authors working in conservation and the relations between man and nature, and more particularly its wildlife. Stemming from a call for contributions directed at young active researchers in Central.Africa, this special issue is as diverse as the themes developed in conservation of this region. >From plains Gorillas of Cameroon to bushmeat consumption in Gabon and the participative management in Congo, intrepid scientists offer us an anthology of fascinating stories. Scattered at the edge of dense forests, in remote and sometimes dangerous areas, these researchers raise numerous questions about the future of wildlife in this part of the globe. A frightening future, since the threats seem more numerous than the solutions. Nevertheless, these articles also deliver a positive vision of the situation. They demonstrate the will of enthusiast conservationists to fight relentlessly for the preservation of our ecosystems. They also demonstrate the increasing implication of researchers from those regions to protect their incredible heritage and reconcile man and nature. If figures are disturbing and human population grows and expands perpetually, particularly in these countries, the interest for

  5. Central Bank Independence, Transparency and Accountability Indexes: a Survey

    Directory of Open Access Journals (Sweden)

    Dumiter Florin Cornel

    2014-06-01

    Full Text Available Recently, the remarkable trend upon central bank independence and the efficient monetary policy were seriously highlighted in the monetary economics field. Starting from 1990s’ central bank independence was at the core of policy making and central banking problems, because of the widespread economical, political, personal and budgetary autonomy of the central bank. Nowadays, we can observe an increasing trend upon central bank transparency, for evaluating more accurate the central bank’s performances by the wide public, mass-media and financial markets. Consequently, a central bank must encompass a high degree of accountability and responsibility, because of the final liability in case of failure. In this paper we present, analyze and assess the construction of the most important indices regarding central bank independence, transparency and accountability in a chronological manner, presenting also the advantages and disadvantages of these indices related to actual practices of central banks. Moreover, we analyze the analytical results of the empirical testing of these indices with a considerable impact upon the developed and developing country group. In regard with the empirical results of different authors, we suggest the importance and the necessity for constructing an aggregate index for measuring central bank independence, transparency and accountability, based on de jure stipulations and the actual practices of the central banks.

  6. Central Safety Department, annual report 1987

    International Nuclear Information System (INIS)

    The Central Safety Department is responsible for handling all problems of radiation protection, safety and security of the institutes and departments of the Karlsruhe Nuclear Research Center, for waste water activity measurements and environmental monitoring of the whole area of the Center, and for research and development work mainly focusing on nuclear safety and radiation protection measures. The r+d work concentrates on the following aspects: physical and chemical behaviour of biologically particularly active radionuclides, behaviour of HT in the air/plan/soil system, biophysics of multicellular systems, improvement in radiation protection measurement and personnel dosimetry. This report gives details of the different duties, indicates the results of 1987 routine tasks and reports about results of investigations and developments of the working groups of the Department. (orig./HP)

  7. Resources Centralization System for Grid Resources

    Directory of Open Access Journals (Sweden)

    Zahraa F. Muhsem

    2013-09-01

    Full Text Available The increasing expansion of communications that is characterized by quality and availability led to interest on grid computing paradigm. The grid computing solves large-scale scientific problems, by providing the feature of sharing and selecting of various resources accessibility and utility. These resources solve intensive problems by increasing the computation and storage power. This study focuses on system with centralized resources for managing the grid resources. The proposed idea will create a resource list, which includes the resource history that will help the user to search for resources. The proposal resources list system will improve the resource serving by showing the most resources used and will save the time search time for the job request, by these points we will improve the quality of the user jobs execution and the quality type of the used resources.

  8. Greening File Distribution: Centralized or Distributed?

    CERN Document Server

    Verma, Kshitiz; Anta, Antonio Fernández; Rumín, Rubén Cuevas; Azcorra, Arturo

    2011-01-01

    Despite file-distribution applications are responsible for a major portion of the current Internet traffic, so far little effort has been dedicated to study file distribution from the point of view of energy efficiency. In this paper, we present a first approach at the problem of energy efficiency for file distribution. Specifically, we first demonstrate that the general problem of minimizing energy consumption in file distribution in heterogeneous settings is NP-hard. For homogeneous settings, we derive tight lower bounds on energy consumption, and we design a family of algorithms that achieve these bounds. Our results prove that collaborative p2p schemes achieve up to 50% energy savings with respect to the best available centralized file distribution scheme. Through simulation, we demonstrate that in more realistic cases (e.g., considering network congestion, and link variability across hosts) we validate this observation, since our collaborative algorithms always achieve significant energy savings with res...

  9. Interceptive management of winged maxillary central incisors

    Directory of Open Access Journals (Sweden)

    Mamta Dali

    2013-01-01

    Full Text Available Introduction: Winged maxillary incisors are a well-recognized clinical finding, which can result in psychological trauma to children at growing age. Interceptive treatment is usually carried out in mixed dentition period in order to reduce the severity of a developing malocclusion in future. Case Report: This paper reports a case of 6-years-old female patient with winged maxillary central incisor being treated with derotation technique using the beggs brackets along with nance palatal arch space maintainer. Discussion: The major advantages in carrying out this treatment with fixed brackets are the ease with which the force magnitude and vector can be controlled much more precisely than with a removable appliance, minimal discomfort to the patient and reduces the need for patient co-operation.

  10. ITER central solenoid model coil impregnation optimization

    Science.gov (United States)

    Schutz, J. B.; Munshi, N. A.; Smith, K. B.

    The success of the vacuum-pressure impregnation of the International Thermonuclear Experimental Reactor central solenoid is critical to success of the magnet system. Analysis of fluid flow through a fabric bed is extremely complicated, and complete analytical solutions are not available, but semiempirical methods can be adapted to model these flows. Several of these models were evaluated to predict the impregnation characteristics of a liquid resin through a mat of reinforcing glass fabric, and an experiment was performed to validate these models. The effects of applied pressure differential, glass fibre volume fraction, resin viscosity and impregnation time were examined analytically. From the results of this optimization, it is apparent that use of elevated processing temperature resin systems offer significant advantages in large scale impregnation due to their lower viscosity and longer working life, and they may be essential for large scale impregnations.

  11. Directional layouts in central lowland Maya settlement

    DEFF Research Database (Denmark)

    Bevan, Andrew; Jobbová, Eva; Helmke, Christophe;

    2013-01-01

    This paper suggests the existence of non-random, directional patterns in the location of housemounds across the Late Classic Maya settlement landscape at Baking Pot, Belize, and then explores the wider implications of this patterning in the central Maya lowlands. It introduces an anisotropic method......, by implication, also a set of routes running throughout the housemound landscape and local Maya neighbourhoods during the site’s Late and Terminal Classic history. Furthermore, different possible alignments in different parts of the site are tentatively regarded as an indication of shifting orientations...... to localised grids, following the shift in alignment of monumental architecture, as the settlement landscape expanded over time. Finally, we discuss the implications of these findings with respect to the broader interpretation of Maya settlement patterns....

  12. Central configurations, periodic orbits, and Hamiltonian systems

    CERN Document Server

    Llibre, Jaume; Simó, Carles

    2015-01-01

    The notes of this book originate from three series of lectures given at the Centre de Recerca Matemàtica (CRM) in Barcelona. The first one is dedicated to the study of periodic solutions of autonomous differential systems in Rn via the Averaging Theory and was delivered by Jaume Llibre. The second one, given by Richard Moeckel, focusses on methods for studying Central Configurations. The last one, by Carles Simó, describes the main mechanisms leading to a fairly global description of the dynamics in conservative systems. The book is directed towards graduate students and researchers interested in dynamical systems, in particular in the conservative case, and aims at facilitating the understanding of dynamics of specific models. The results presented and the tools introduced in this book include a large range of applications.

  13. Central Tracking Detector Based on Scintillating Fibres

    CERN Multimedia

    2002-01-01

    Scintillating fibres form a reasonable compromise for central tracking detectors in terms of price, resolution, response time, occupancy and heat production. \\\\ \\\\ New fluorescents with large Stokes shifts have been produced, capable of working without wavelength shifters. Coherent multibundles have been developed to achieve high packing fractions. Small segments of tracker shell have been assembled and beam tests have confirmed expectations on spatial resolution. An opto-electronic delay line has been designed to delay the track patterns and enable coincidences with a first level trigger. Replacement of the conventional phosphor screen anode with a Si pixel chip is achieved. This tube is called ISPA-tube and has already been operated in beam tests with a scintillating fibres tracker. \\\\ \\\\ The aim of the proposal is to improve hit densities for small diameter fibres by increasing the fraction of trapped light, by reducing absorption and reflection losses, by reflecting light at the free fibre end, and by inc...

  14. Dreyfusia nordmannianae in Northern and Central Europe

    DEFF Research Database (Denmark)

    Ravn, Hans Peter; Havill, N.P.; Akbulut, S.;

    2013-01-01

    , with the purpose of selecting agents for classical biological control in Europe. The literature review suggested that the most promising agent was the Chamaemyiidae fly, Leucopis hennigrata. A new survey in D. nordmannianae's area of origin – Turkey, Georgia and Russia – showed that L. hennigrata was present...... in all localities. It was particularly abundant in Turkey, where its impact on populations of D. nordmannianae appears to be high. Its use as a biological control agent is discussed, as well as other biological control strategies......The silver fir woolly adelgid, Dreyfusia nordmannianae, is the most severe pest occurring on Abies nordmanniana in Central and Northern Europe. The adelgid is particularly damaging to trees in Christmas tree plantations. Dreyfusia nordmannianae is native to the Caucasus region and alien to Europe...

  15. Central nervous system lupus erythematosus in childhood

    Energy Technology Data Exchange (ETDEWEB)

    Yokota, Shumpei; Kimura, Kazue; Yoshida, Naotaka; Mitsuda, Toshihiro; Ibe, Masa-aki; Shimizu, Hiroko (Yokohama City Univ. (Japan). Faculty of Medicine)

    1989-12-01

    Clinical features of central nervous system (CNS) invlvement in childhood systemic lupus erythematosus (SLE) was investigated. Neuropsychiatric manifestations including seizures, chorea, headache, overt psychosis, tremor, increase of muscle spastisity, and disturbed memory were found in 47% of 15 patients with SLE. There was a well correlatin between CNS abnormalities and SLE disease activity judged by serum complement levels and anti-nuclear antibody and anti-DNA antibody titers. The administration of Prednisolon was effective for the treatment of these CNS abnormalities and steroid psychosis was rare in the present study. EEG abnormalities involving diffuse slowing and slowing bursts were found in 73% of the patients. Cranial CT scan revealed basel ganglia calcifications in 2 patients, and marked brain atrophy in 3 patients. This study indicated that in the long term following of SLE children CNS abnormalities need to be serially checked by EEG and cranial CT scans as well as serological investigations. (author).

  16. East Central Uplift Belt of Junggar Basin

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    @@ Mosuowandong ( Z3 ) and Dongdaohaizi (Z4) are two bidding blocks located in the east part of central uplift Belt, the hinterland of Junggar Basin. Xinjiang Uygur Autonomous Region. It totally covers an area of 8 100km2. Topographically, the two blocks are quite gentle with elevation of 380-400 m on average. The north part is desert and the south area is good for farming. There are three ephemeral streams flowing across the desert from south to north. The ground water is buried at the depth ranging from 6 to 8 m. It belongs to continental climate with the annually averaged precipitation of 80 mm. The traffic is rather convenient in the south part of both blocks. There are several sand-paved roads and two asphalt roads connected with the highway from Karamay to Urumqi City.

  17. PHENIX central arm particle ID detectors

    Energy Technology Data Exchange (ETDEWEB)

    Aizawa, M.; Akiba, Y.; Begay, R.; Burward-Hoy, J.; Chappell, R.B.; Chi, C.Y.; Chiu, M.; Chujo, T.; Crook, D.W.; Danmura, A.; Ebisu, K.; Emery, M.S.; Enosawa, K.; Esumi, S.; Ferrierra, J.; Frawley, A.D. E-mail: frawley@fsuhip.physics.fsu.edu; Griffin, V.; Hamagaki, H.; Hara, H.; Hayano, R.S.; Hayashi, H.; Hemmick, T.K.; Hibino, M.; Higuchi, R.; Hirano, T.; Hoade, R.; Hutter, R.; Inaba, M.; Jones, K.; Kametani, S.; Kato, S.; Kennedy, M.; Kikuchi, J.; Kiyomichi, A.; Koseki, K.; Kurata-Nishimura, M.; Kurita, K.; Kuroki, Y.; Matsumoto, T.; Miake, Y.; Miyamoto, Y.; Moscone, G.G.; Nagasaka, Y.; Nishimura, S.; Ono, M.; Oyama, K.; Raynis, R.; Sakaguchi, T.; Sakai, S.; Sako, H.; Salomone, S.; Sato, S.; Shigaki, K.; Shimada, T.; Suzuki-Nara, M.; Tamai, M.; Tanaka, Y.; Tsuruoka, H.; Urasawa, S.; Ushiroda, T.; Walker, J.W.; Wang, S.; Wintenberg, A.L.; Wright, L.W.; Yagi, K.; Yokota, Y.; Young, G.R

    2003-03-01

    The Ring-Imaging Cherenkov (RICH) and the Time-of-Flight (ToF) systems provide identification of charged particles for the PHENIX central arm. The RICH is located between the inner and outer tracking units and is one of the primary devices for identifying electrons among the very large number of charged pions. The ToF is used to identify hadrons and is located between the most outer pad chamber (PC3) and the electromagnetic calorimeter. A Time Zero (T0) counter that enhances charged particle measurements in p-p collisions is described. Details of the construction and performance of both the RICH, ToF and T0 are given along with typical results from the first PHENIX data taking run.

  18. Pediatric central nervous system vascular malformations

    Energy Technology Data Exchange (ETDEWEB)

    Burch, Ezra A. [Brigham and Women' s Hospital, Department of Radiology, Boston, MA (United States); Orbach, Darren B. [Boston Children' s Hospital, Neurointerventional Radiology, Boston, MA (United States)

    2015-09-15

    Pediatric central nervous system (CNS) vascular anomalies include lesions found only in the pediatric population and also the full gamut of vascular lesions found in adults. Pediatric-specific lesions discussed here include infantile hemangioma, vein of Galen malformation and dural sinus malformation. Some CNS vascular lesions that occur in adults, such as arteriovenous malformation, have somewhat distinct manifestations in children, and those are also discussed. Additionally, children with CNS vascular malformations often have associated broader vascular conditions, e.g., PHACES (posterior fossa anomalies, hemangioma, arterial anomalies, cardiac anomalies, eye anomalies and sternal anomalies), hereditary hemorrhagic telangiectasia, and capillary malformation-arteriovenous malformation syndrome (related to the RASA1 mutation). The treatment of pediatric CNS vascular malformations has greatly benefited from advances in endovascular therapy, including technical advances in adult interventional neuroradiology. Dramatic advances in therapy are expected to stem from increased understanding of the genetics and vascular biology that underlie pediatric CNS vascular malformations. (orig.)

  19. Jets, magnetic fields and the central engine

    International Nuclear Information System (INIS)

    Reviewing recent observations of jets unconfined by external pressure, the author suggests that self-confinement may be common. This requires current-carrying jets with helical magnetic fields. Such beams occur in the laboratory, in lightning, and in the Crab Nebula, where currents are apparently carried over distances greater than a light year. Self-confined jets require a significant torodial magnetic field emerging from the nozzle. The author suggests that the parallel/azimuthal magnetic field ratio may be the crucial nozzle parameter, causing asymmetries. Helical field configurations have remarkable stability properties and can evolve naturally as synchrotron losses in the jet lead to minimizing Lorentz forces. Current-carrying jets may provide a valuable clue to the physics of the central source. (Auth.)

  20. (Prérif central, Maroc septentrional

    Directory of Open Access Journals (Sweden)

    Abdelghani Gartet

    2005-01-01

    Full Text Available El artículo tiene por objeto evaluar la degradación específi ca, y especialmente cuantifi car la carga de transporte sólido, en la cuenca del oued Lebène (Prérif central, caracterizada por altas tasas de erosión hídrica. La fuerte erosionabilidad de las rocas, la agresividad climática y las frecuentes variaciones de caudal hacen que el volumen de los materiales transportados por el Lebène alcancen una magnitud considerable. La irregularidad espacio-temporal de las precipitaciones y caudales condicionan el volumen de los transportes sólidos, de ahí las estrechas correlaciones existentes entre las tres variables. Los análisis relativos a la turbidez de las aguas y a la naturaleza granulométrica de los sedimentos refuerzan dicha relación.