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Sample records for central mali based

  1. Mali.

    Science.gov (United States)

    1986-04-01

    Mali's population stood at 7.5 million in 1985, with an annual growth rate of 2.7%. The infant mortality rate was 152/1000 live births and life expectancy was 45 years. Literacy was only 10%. Of the work force of 3.5 million, 73% were engaged in agriculture, 12% were employed in industry and commerce, and 16% were in the service sector. Mali's GDP was US$1.2 billion in 1981, with an annual growth rate of 1.5% and a per capita income (1984) of $190. Mali is among the 10 poorest countries of the world. The agricultural sector, which provides 43% of the gross domestic product, is dominated by small-scale traditional farming and there have been problems with droughts. Deposits of several ores exist but are not mined because of inadequate transportation and power facilities. Mali is a single-party republic governed by the Democratic Union of the Malian People. PMID:12178146

  2. Farmers on the move: mobility, access to land and conflict in Central and South Mali

    OpenAIRE

    Nijenhuis, K.

    2013-01-01

    In contrast to their sedentary image, farmers in Central and South Mali are surprisingly mobile. Many have settled in scattered farming hamlets where they are rapidly expanding the areas under agriculture. This study focuses on farmers’ mobility in relation to accessing land in two regions in Mali where farming conditions are very different regarding rainfall, population growth and opportunities for income generation. It is shown that differences in farming conditions in the two regions have ...

  3. A pastoral women's economy in crisis : the Fulbe in central Mali

    NARCIS (Netherlands)

    Bruijn, de M.E.

    1995-01-01

    This paper compares the economy of agropastoral Fulbe women in central Mali before and after the 1973 and 1985 droughts. The position of pastoralist women depends mainly on access to livestock, and more precisely on access to milk. Rules governing access to milk vary considerably between different p

  4. The hearthhold in pastoral Fulbe society, central Mali : social relations, milk and drought

    NARCIS (Netherlands)

    Bruijn, de M.E.

    1997-01-01

    In pastoral Fulbe society in central Mali women had, and to some degree still have, an important social and economic role, concentrated on a 'milk economy' organized through a female-headed, women-centred unit, called 'fayannde' or 'hearthhold'. In a society of seminomadic pastoralists who live most

  5. Analysis of the potential for sustainable, cassava-based bioethanol production in Mali

    DEFF Research Database (Denmark)

    Rasmussen, Kjeld; Bruun, Thilde Bech; Birch-Thomsen, Torben;

    The present project is covered in five main reports: 1) Analyses of the potential for sustainable, cassava-based bio-ethanol production in Mali 2) Agricultural residues for energy production in Mali 3) Pre-feasibility study for an electric power plant based on rice straw 4) Estimation of wind...

  6. The sustainability of cassava-based bioethanol production in southern Mali

    DEFF Research Database (Denmark)

    Rasmussen, Kjeld; Birch-Thomsen, Torben; Bruun, Thilde Bech;

    2015-01-01

    of cassava-based bioethanol production in southern Mali, assessing its environmental, economic and social sustainability. Results demonstrate that environmental sustainability of cassava-based bioethanol production depends on the ‘baseline’ chosen: Compared to the situation before the decline in cotton...... production 10 years ago, the carbon stocks will increase. However, if compared to the current situation, where considerable carbon stocks have accumulated in fallow fields, the loss of carbon will be substantial. Increased cassava production will create greater incomes and better temporal distribution...... of labour input. Analysis of the significance of current cassava production for food security shows that bioethanol production should be based on the attiéké variety of cassava, thereby avoiding interference with the important role of the bonouma in assuring food security in northern Mali. The key factor...

  7. Arid ways : Cultural understandings of insecurity in Fulbe Society, Central Mali = Leven met droogte : culturele expressie van onzekerheid bij de Fulbe in Centraal - Mali

    OpenAIRE

    Dijk, van, F.J.H.; Bruijn, de, NG Dick

    1995-01-01

    You can obtain a copy of this thesis through your local bookstore or directly from:Thela Thesis, Prinseneiland 305, 1013 LP  Amsterdam.E-mail: studie is het verslag van bijna twee jaar veldwerk bij de Fulbe van Centraal Mali, meer in het bijzonder de Fulbe die een gebied bewonen ten zuiden van de bergketen tussen het Bandiagara plateau en Mont Hommbori. Lokaal wordt het gebied de Hayre genoemd, wat bergen of stenen betekent in het Fulfulde, de taal van de Fulbe (zie ...

  8. A remote sensing-based irrigation performance assessment: a case study of the Office du Niger in Mali

    NARCIS (Netherlands)

    Zwart, S.J.; Leclert, L.M.C.

    2009-01-01

    The irrigation performance of the Office du Niger in Mali, a large-scale rice-based irrigation scheme, was analysed with the use of remote sensing technology. The major advantage of remote sensing derived data over field measured data is that it provides system-wide, spatially distributed and object

  9. Pre-feasibility study for an electric power plant based on rice straw. [Mali

    Energy Technology Data Exchange (ETDEWEB)

    Fock, F. [Ea Energy Analysis, Copenhagen (Denmark); Nygaard, I. [Technical Univ. of Denmark. DTU Management Engineering, UNEP Risoe Centre on Energy, Climate and Sustainable Development, Roskilde (Denmark); Maiga, A.; Kone, B.; Kamissoko, F.; Coulibaly, N.; Ouattara, O.

    2012-11-15

    The main objective is to make a first evaluation regarding if it's technically possible, economically viable, sustainable and recommendable to build a rice straw/hulls fired power plant in Niono in Mali. Based on the available resource of rice straw and the possibilities for connecting to the grid it has been chosen to analyse a 5 MW power plant in the project. For technical reasons the rice straw should be the main fuel, but rice hulls can be used for co-firing. Up to around 20% of the fuel in the plant can be rice hulls instead of rice straw. A number of different biomass power production technologies have been evaluated in the project. This includes: 1) Grate fired boiler. 2) Bubbling fluidised bed. 3) Circulating fluidised bed. 4) Dust fired boiler. 5) Gasification. 6) Stirling engine. 7) Organic Rankine Cycle. Grate firing is the most relevant technology in this case, due to the fuel, the size of the power plant, the demand for electricity only and not heat, the demand for a robust and well proven technology. For a grate fired plant a calculation of the thermodynamic process of the power plant has been carried out in order to determine the electrical efficiency of the plant. The case consists of a 5 MW grate fired power plant with steam turbines and air cooled condenser resulting in an efficiency of 24.6% at full load (20% as yearly average). Investment costs and costs for O and M have been assumed based on experience from Danish power plants but adjusted for local conditions in Mali. The costs for collecting and transporting the rice straw and for the ash disposal have been specifically estimated in this project. The average cost of capital has been estimated based on assumptions on equity, international loans and local loans/bank finance. Based on the investment, the cost of O and M, fuel, ash disposal and the financial assumptions, a cash flow analysis is made in order to calculate the power price resulting in a Net Present Value (NPV) of the

  10. Croissance de Auchenoglanis occidentalis (Pisces, Claroteidae dans le Delta Central du Niger (Mali, Afrique de l'ouest

    Directory of Open Access Journals (Sweden)

    Niaré, T.

    2013-01-01

    Full Text Available Growth of Auchenoglanis occidentalis (Pisces, Claroteidae in the Central Delta of Niger River Flood Plain (Mali, West Africa. Growth biology of Auchenoglanis occidentalis (Valenciennes, 1840 is studied from individuals monthly sampled on two different annual cycles (1991 and 1997 in the fishing port of Mopti. Individual age of fishes was determined by squelettochronology. Chronological follow-up of relative margin diameter (dr of spine ray section was used for validation of the periodicity of annulus formation. Only one annulus is formed annually. Period of growth recovery shows an individual variability with an early starting up from the lowwater level, in May. The seasonal cycle of growth of this benthic fish, A. occidentalis, depends more on the availability of the trophic resources than of abiotic factors. However, the optimal period of growth always remains the high-water one in this river with flood plain. Fishes condition factor's varies between 1.97±0.27 à 2.57±0.41. Year x season interaction affects this parameter. Growth realized during the first year (189.17±4.57 and 261.25±12.19 mm as well as the later growths depend on hydrological conditions and are influenced by fishing pressure. Presence of 3+ age class fishes shows that demographic structure is not qualitatively modified despite changes arisen in the Delta.

  11. Variability of half-sib progeny properties as the base of Moesian beech (Fagus moesiaca (Maly) Czeczott) breeding

    OpenAIRE

    Ocokoljić Mirjana; Anastasijević Nebojša

    2004-01-01

    Based on the analysis of several morphological features and phenotype characteristics of seedlings in the juvenile test with 10 half-sib lines of Moesian beech (Fagus moesiaca (Maly) Czeczott), this paper gives the guidelines for further breeding and production of planting material for urban coenoses and the establishment of special purpose plantations of this species. The comparative analysis enabled the identification of the extreme planting material for further breeding programs aiming at ...

  12. The effect of cassava-based bioethanol production on above-ground carbon stocks: A case study from Southern Mali

    International Nuclear Information System (INIS)

    Increasing energy use and the need to mitigate climate change make production of liquid biofuels a high priority. Farmers respond worldwide to this increasing demand by converting forests and grassland into biofuel crops, but whether biofuels offer carbon savings depends on the carbon emissions that occur when land use is changed to biofuel crops. This paper reports the results of a study on cassava-based bioethanol production undertaken in the Sikasso region in Southern Mali. The paper outlines the estimated impacts on above-ground carbon stocks when land use is changed to increase cassava production. The results show that expansion of cassava production for bioethanol will most likely lead to the conversion of fallow areas to cassava. A land use change from fallow to cassava creates a reduction in the above-ground carbon stocks in the order of 4–13 Mg C ha−1, depending on (a) the age of the fallow, (b) the allometric equation used and (c) whether all trees are removed or the larger, useful trees are preserved. This ‘carbon debt’ associated with the above-ground biomass loss would take 8–25 years to repay if fossil fuels are replaced with cassava-based bioethanol. - Highlights: ► Demands for biofuels make production of cassava-based bioethanol a priority. ► Farmers in Southern Mali are likely to convert fallow areas to cassava production. ► Converting fallow to cassava creates reductions in above-ground carbon stocks. ► Estimates of carbon stock reductions include that farmers preserve useful trees. ► The carbon debt associated with above-ground biomass loss takes 8–25 years to repay.

  13. Networking in the Desert - Operational and Analytical Challenges for MINUSMA in Mali

    DEFF Research Database (Denmark)

    Haugegaard, Rikke

    This paper will initiate a discussion of the operational and analytical challenges in understanding network dynamics in Mali, and how these dynamics can be seen as one source of conflict in Mali. The paper is based on a field visit to Mali in 2014....

  14. Artemisinin-based combinations versus amodiaquine plus sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Faladje, Mali

    Directory of Open Access Journals (Sweden)

    Traore Boubacar

    2009-01-01

    Full Text Available Abstract Background Because of the emergence of chloroquine resistance in Mali, artemether-lumefantrine (AL or artesunate-amodiaquine (AS+AQ are recommended as first-line therapy for uncomplicated malaria, but have not been available in Mali until recently because of high costs. Methods From July 2005 to January 2006, a randomized open-label trial of three oral antimalarial combinations, namely AS+AQ, artesunate plus sulphadoxine-pyrimethamine (AS+SP, and amodiaquine plus sulphadoxine-pyrimethamine (AQ+SP, was conducted in Faladje, Mali. Parasite genotyping by polymerase chain reaction (PCR was used to distinguish new from recrudescent Plasmodium falciparum infections. Results 397 children 6 to 59 months of age with uncomplicated Plasmodium falciparum malaria were enrolled, and followed for 28 days to assess treatment efficacy. Baseline characteristics were similar in all three treatment groups. The uncorrected rates of adequate clinical and parasitologic response (ACPR were 55.7%, 90.8%, and 97.7% in AS+AQ, AS+SP, and AQ+SP respectively (p Conclusion The combination of AQ+SP provides a potentially low cost alternative for treatment of uncomplicated P. falciparum infection in Mali and appears to have the added value of longer protective effect against new infection.

  15. Glasses for Mali

    CERN Multimedia

    PH Department

    2008-01-01

    We are collecting old pairs of glasses to take out to Mali, where they can be re-used by people there. The price for a pair of glasses can often exceed 3 months salary, so they are prohibitively expensive for many people. If you have any old spectacles you can donate, please put them in the special box in the ATLAS secretariat, Bldg.40-4-D01 before the Christmas closure on 19 December so we can take them with us when we leave for Africa at the end of the month. (more details in ATLAS e-news edition of 29 September 2008: http://atlas-service-enews.web.cern.ch/atlas-service-enews/news/news_mali.php) many thanks! Katharine Leney co-driver of the ATLAS car on the Charity Run to Mali

  16. Analyses of effects of α-cembratrien-diol on cell morphology and transcriptome of Valsa mali var. mali.

    Science.gov (United States)

    Yan, Ning; Du, Yongmei; Liu, Xinmin; Zhang, Hongbo; Liu, Yanhua; Shi, John; Xue, Sophia Jun; Zhang, Zhongfeng

    2017-01-01

    The objective of this work was to study the underlying mechanisms of growth inhibition of Valsa mali var. mali, the causative pathogen of apple tree canker disease, by α-cembratrien-diol. The half maximal inhibitory concentration of α-cembratrien-diol against V. mali var. mali is 18.0mg/L. Treatment of V. mali var. mali with α-cembratrien-diol resulted in various mycelial and cellular abnormalities, and the up- and down-regulation of 94 and 170 differentially expressed genes, respectively. Gene Ontology term enrichment analysis revealed that α-cembratrien-diol substantially altered the expression of genes involved in the redox process, tetrapyrrole binding, coenzyme binding, heme binding, and iron binding. Kyoto Encyclopedia of Genes and Genomes enrichment analysis also showed significant enrichment of specific metabolic pathways involving the set of differentially expressed genes. The present study will assist in the development of alternative α-cembratrien-diol-based biological control agents and ultimately facilitate organic apple production. PMID:27507455

  17. Etre touareg au Mali

    OpenAIRE

    Edmond BERNUS

    1992-01-01

    Après une présentation générale de leur espace, de leur culture commune, des stéréotypes dont ils font l'objet, les Touaregs maliens sont décrits dans leurs diversités régionales. Les révoltes passées, celle de Firhoun, le héros de 1916, puis celle de l'Adrar des Iforas en 1963-64 contre le gouvernement de Modibo Keita, précédent la révolte qui s'étend depuis 1990 au Niger et au Mali avec des guerriers sachant manier armes et voitures. Attaques et répression sauvage se succèdent dans une spir...

  18. Mali: Visions of War

    Directory of Open Access Journals (Sweden)

    Roland Marchal

    2013-06-01

    Full Text Available Political elites in Bamako articulate different understandings of the war in northern Mali, though share the same view on the restoration of Malian sovereignty. Those visions are deeply rooted in an assessment of the past failed peace agreements with Tuareg groups, a focus on social and ethnic differentiations that emphasize the role of Kidal and the will to avoid major reforms in dealing with key issues such as the efficiency of the political system, the role of Islam in the Malian polity and the complicated relations between Bamako and its neighbours. The status of AQIM in the current crisis, contrary to the international narrative, is downplayed while other armed groups, in particular the MNLA, are seen as the real, and, often, only threat.

  19. Primary Study of Viticultural and Oenological Characteristics of ‘Plavac Mali Sivi’ and its Comparison with ‘Pošip’ and ‘Grk’ in the Central Dalmatia

    Directory of Open Access Journals (Sweden)

    Goran Zdunić

    2012-03-01

    Full Text Available Characterization of ‘Plavac Mali Sivi’, a mutant of ‘Plavac Mali’ noir, having grey berry skin colour, and its comparison with well-known white cultivars in the region of Dalmatia ‘Pošip’ and ‘Grk’ were performed in this study. Basic viticultural and oenological characteristics were evaluated in three growing seasons in the grape germplasm repository. ‘Plavac Mali Sivi’ showed lower yield per vine, and cluster weight than other two cultivars. Number of berries per cluster differed significantly among cultivars. ‘Plavac Mali Sivi’ had significantly lower total acidity than ‘Pošip’ and ‘Grk’. High oenological variability among these three cultivars was found. ‘Plavac Mali Sivi’ had a relatively high content of alcohol (13.9 vol.% and equal to ‘Pošip’ (13.9 vol.%, and significantly different from the ‘Grk’ (12.8 vol.%. The highest content of dry extract was determined at ‘Pošip’, while ‘Plavac Mali Sivi’ and ‘Grk’ were not significantly different. The results of this study indicate the possibility of providing a new white wine for the market from recently propagated mutant ‘Plavac Mali Sivi’ in the region of Dalmatia and justify further technological investigation.

  20. Enhanced Diagnosis of Pneumococcal Bacteremia Using Antigen- and Molecular-Based Tools on Blood Specimens in Mali and Thailand: A Prospective Surveillance Study.

    Science.gov (United States)

    Moïsi, Jennifer C; Moore, Matthew; Carvalho, Maria da Gloria; Sow, Samba O; Siludjai, Duangkamon; Knoll, Maria Deloria; Tapia, Milagritos; Baggett, Henry C

    2016-02-01

    Prior antibiotic use, contamination, limited blood volume, and processing delays reduce yield of blood cultures for detection of Streptococcus pneumoniae. We performed immunochromatographic testing (ICT) on broth from incubated blood culture bottles and real-time lytA polymerase chain reaction (PCR) on broth and whole blood and compared findings to blood culture in patients with suspected bacteremia. We selected 383 patients in Mali and 586 patients in Thailand based on their blood culture results: 75 and 31 were positive for pneumococcus, 100 and 162 were positive for other pathogens, and 208 and 403 were blood culture negative, respectively. ICT and PCR of blood culture broth were at least 87% sensitive and 97% specific compared with blood culture; whole blood PCR was 75-88% sensitive and 96-100% specific. Pneumococcal yields in children 99% of additional cases detected by whole blood PCR, and from 0.07% to 5.1% in Thailand with two-thirds of additional cases identified by ICT. Compared with blood culture, ICT and lytA PCR on cultured broth were highly sensitive and specific but their ability to improve pneumococcal identification varied by site. Further studies of these tools are needed before widespread implementation. PMID:26643535

  1. Regional Security Complex of Mali

    OpenAIRE

    Kristensen, Klaus; Juhl, Søren; Jonas, Berg; David, Fisiha; Rasmus, Beck Nørbjerg Hansen

    2012-01-01

    Mali has been described as a somewhat stable country, yet recent events have turned Mali into a country of conflict. This we found interesting, so to get a better understanding of the situation, we wanted to get a more clear comprehension of the involved actors and the dynamics of the conflict. The interest to understand their internal relationship and what the reasons to the conflict are is the foundation for our motivation to the further study of this conflict. We have chosen four actor...

  2. Study Area 1 (Mali) Report

    International Nuclear Information System (INIS)

    Mali is a landlocked country which covers 1,211,238 km2 and contains around 10 million people. Mali is cited among the less advanced countries with GDP of 156,264 CFA(220 US Dollars) per person. At least 75% of the population live in the rural areas and depend mainly on agriculture for their livelihood. The contribution of agriculture to GDP is about 50%. The population increase rate is 3.4% , while the GDP increase rate is about ----------. One of the major constraints to the integrated rural development in the portion of Malian territory (240,000 km2 or 16%) infested with tsetse flies is the presence of trypanosomosis. Mali is infested with only three types of tsetse flies: a regressing G.morsitans submorsitans in the declining savannah and the persisting G.palpalis gambiensis and G.tachinoides alongside the river systems. G.morsitans submorsitans, being continuously pushed by the cultivation of new lands, tsetse control in Mali is likely to be restricted to a battle against reverine tsetse flies. According to the criteria set up by PAAT, the cotton belt in the southern part of Mali which has a high potential for agricultural and livestock production, has been identified as a priority area for tsetse control. The development of this area is the responsibility of the 'Compagnie Malienne pour le Developpement des Textiles' known as CMDT. CMDT is a society owned by the Government of Mali (60%) and the 'Compagnie Francaise pour le Developpement des Textiles' known as CFDT (40%). Its primary mission was the promotion of the cotton business. Nowadays its activities have diversified and cover many other domains of socio-economic development such as food security, rural infrastructure (roads and bridges), public health, education, community organisation, etc. The present work is a contribution to a study examining the costs and the benefits of tsetse eradication and ensuing agricultural development for a small project (17,000 sq km) at the Mali - Burkina Faso border.

  3. The Sign Language Situation in Mali

    Science.gov (United States)

    Nyst, Victoria

    2015-01-01

    This article gives a first overview of the sign language situation in Mali and its capital, Bamako, located in the West African Sahel. Mali is a highly multilingual country with a significant incidence of deafness, for which meningitis appears to be the main cause, coupled with limited access to adequate health care. In comparison to neighboring…

  4. Mali. Musique bambara du Baninko

    OpenAIRE

    Zanetti, Vincent

    2011-01-01

    Dans le Mali contemporain, le groupe ethnique le plus important numériquement est celui que la littérature ethnographique a définitivement contribué à faire connaître sous le nom de «Bambara». Installés sur un vaste territoire recouvrant grosso modo le quart sud-est du pays, les Bambara, qui dans leur propre langue se désignent en fait sous le nom de bamananw (au singulier: bamanan), se distinguent les uns les autres selon leur répartition géographique, dans les trois régions suivantes: Beled...

  5. Horizontal gene transfer drives adaptive colonization of apple trees by the fungal pathogen Valsa mali

    Science.gov (United States)

    Yin, Zhiyuan; Zhu, Baitao; Feng, Hao; Huang, Lili

    2016-01-01

    Horizontal gene transfer (HGT) often has strong benefits for fungi. In a study of samples from apple canker in Shaanxi Province, China, diverse microbes, along with the necrotrophic pathogen Valsa mali, were found to colonize the apple bark, thus providing ample opportunity for HGT to occur. In the present study, we identified 32 HGT events in V. mali by combining phyletic distribution-based methods with phylogenetic analyses. Most of these HGTs were from bacteria, whereas several others were from eukaryotes. Three HGTs putatively functioned in competition with actinomycetes, some of which showed a significant inhibitory effect on V. mali. Three HGTs that were probably involved in nitrogen uptake were also identified. Ten HGTs were thought to be involved in pathogenicity because they were related to known virulence factors, including cell wall-degrading enzymes and candidate effector proteins. HGT14, together with HGT32, was shown to contribute to bleomycin resistance of V. mali.These results suggest that HGT drives the adaptive evolution of V. mali. The HGTs identified here provide new clues for unveiling the adaptation mechanisms and virulence determinants of V. mali. PMID:27634406

  6. Mining Taxation; An Application to Mali

    OpenAIRE

    Saji Thomas

    2010-01-01

    Mali’s gold sector is an enclave with weak forward and backward linkages with the rest of the economy. Given the predominance of the fiscal transmission channel, it is important that the design of the mineral tax regime gives the state a fair share of the benefits. Using optimal control theory, this paper estimates that the optimal royalty tax in Mali is about 3.5 percent. By reducing the royalty rate from 6 percent to 3 percent, Mali’s mining code broadly ensures that the risk is shared ...

  7. Estimation of wind and solar resources in Mali

    Energy Technology Data Exchange (ETDEWEB)

    Badger, J.; Kamissoko, F.; Olander Rasmussen, M.; Larsen, Soeren; Guidon, N.; Boye Hansen, L.; Dewilde, L.; Alhousseini, M.; Noergaard, P.; Nygaard, I.

    2012-11-15

    The wind resource has been estimated for all of Mali at 7.5 km resolution using the KAMM/WAsP numerical wind atlas methodology. Three domains were used to cover entire country and three sets of wind classes used to capture change in large scale forcing over country. The final output includes generalized climate statistics for any location in Mali, giving wind direction and wind speed distribution. The modelled generalized climate statistics can be used directly in the WAsP software. The preliminary results show a wind resource, which is relatively low, but which under certain conditions may be economically feasible, i.e. at favourably exposed sites, giving enhanced winds, and where practical utilization is possible, given consideration to grid connection or replacement or augmentation of diesel-based electricity systems. The solar energy resource for Mali was assessed for the period between July 2008 and June 2011 using a remote sensing based estimate of the down-welling surface shortwave flux. The remote sensing estimates were adjusted on a month-by-month basis to account for seasonal differences between the remote sensing estimates and in situ data. Calibration was found to improve the coefficient of determination as well as decreasing the mean error both for the calibration and validation data. Compared to the results presented in the ''Renewable energy resources in Mali - preliminary mapping''-report that showed a tendency for underestimation compared to data from the NASA PPOWER/SSE database, the presented results show a very good agreement with the in situ data (after calibration) with no significant bias. Unfortunately, the NASA-database only contains data up until 2005, so a similar comparison could not be done for the time period analyzed in this study, although the agreement with the historic NASA data is still useful as reference. (LN)

  8. Nonhealing Ulcer: Acroangiodermatitis of Mali

    Directory of Open Access Journals (Sweden)

    Neeraj Varyani

    2011-01-01

    Full Text Available An 18-year-old male presented with a nonhealing wound on left lower limb, pain and swelling over multiple joints, weight loss, and yellowish discoloration of eyes and urine for the past 4 years. On examination, the patient had pallor, icterus, and generalized lymphadenopathy with a nonhealing unhealthy ulcer over left medial malleolus. He had deformed joints with hepatomegaly and splenomegaly. His laboratory investigations were positive for antinuclear antibody (ANA and anticardiolipin antibody (ACLA. Synovial fluid analysis showed inflammatory findings. Biopsy of margin of the ulcer showed findings consistent with Acroangiodermatitis of Mali. The patient was treated with disease-modifying antirheumatic drugs (DMARDs and aspirin for juvenile idiopathic arthritis and secondary antiphospholipid antibody syndrome (APS, respectively. The ulcer was managed conservatively with systemic antibiotics and topical steroids along with limb elevation and compression elastic stockings. The patient's symptoms improved significantly, and he is in our followup.

  9. Travelling hierarchies : roads in and out of slave status in a Central Malian Fulbe network

    NARCIS (Netherlands)

    Pelckmans, L.

    2011-01-01

    Based on rich and wide-ranging data, the thesis describes the sensitive issue of the contemporary emancipation trajectories of agro-pastoralist Fulbe in Central Mali. It explores how people are currently dealing with hierarchies they inherited from past master-slave relations and focuses on the rela

  10. Travelling hierarchies : moving in and out of slave status in a Central Malian FulBe network

    NARCIS (Netherlands)

    Pelckmans, Lotte

    2011-01-01

    Based on rich and wide-ranging data, this thesis describes the sensitive issue of the contemporary emancipation trajectories of agro-pastoralist Fulɓe in Central Mali. It explores how people are currently dealing with hierarchies they inherited from past master-slave relations and focuses on the rel

  11. Travelling hierarchies: Moving in and out of slave status in a Central Malian FulBe network

    NARCIS (Netherlands)

    Pelckmans, L.

    2011-01-01

    Based on rich and wide-ranging data, the thesis describes the sensitive issue of the contemporary emancipation trajectories of agro-pastoralist Fulbe in Central Mali. It explores how people are currently dealing with hierarchies they inherited from past master-slave relations and focuses on the rela

  12. Predicting in-hospital maternal mortality in Senegal and Mali.

    Directory of Open Access Journals (Sweden)

    Cheikh Ndour

    Full Text Available OBJECTIVE: We sought to identify predictors of in-hospital maternal mortality among women attending referral hospitals in Mali and Senegal. METHODS: We conducted a cross-sectional epidemiological survey using data from a cluster randomized controlled trial (QUARITE trial in 46 referral hospitals in Mali and Senegal, during the pre-intervention period of the trial (from October 1st 2007 to October 1st 2008. We included 89,518 women who delivered in the 46 hospitals during this period. Data were collected on women's characteristics, obstetric complications, and vital status until the hospital discharge. We developed a tree-like classification rule (classification rule to identify patient subgroups at high risk of maternal in-hospital mortality. RESULTS: Our analyses confirm that patients with uterine rupture, hemorrhage or prolonged/obstructed labor, and those who have an emergency ante-partum cesarean delivery have an increased risk of in-hospital mortality, especially if they are referred from another health facility. Twenty relevant patterns, based on fourteen predictors variables, are used to predict in-hospital maternal mortality with 81.41% sensitivity (95% CI = [77.12%-87.70%] and 81.6% specificity (95% CI = [81.16%-82.02%]. CONCLUSION: The proposed class association rule method will help health care professionals in referral hospitals in Mali and Senegal to identify mothers at high risk of in-hospital death, and can provide scientific evidence on which to base their decisions to manage patients delivering in their health facilities.

  13. Can the UN Stabilize Mali? Towards a UN Stabilization Doctrine?

    Directory of Open Access Journals (Sweden)

    Arthur Boutellis

    2015-06-01

    Full Text Available Almost two years after the deployment of the United Nations Multidimensional Integrated Stabilization Mission in Mali (MINUSMA in July 2013, the increasing number of asymmetric terrorist attacks targeting UN peacekeepers – in the context of a drawn-out peace process – has raised a number of questions in Mali, the sub-region, and in New York, over the relevance and adequacies of MINUSMA’s mandate and capabilities. It also raises a broader issue, of whether the consent-based UN peacekeeping tool is appropriate and can be effective in carrying out stabilization mandates in such a context and what doctrine such operations should be based on. The UN is indeed under increasing pressure from host countries and some African troop-contributing countries to go on the offensive. Member States have also increasingly recognized terrorism and organized crime as a strategic threat, and while opposed to the UN directly engaging in counterterrorism (CT operations, some may wish to see the UN playing a greater stabilization role following the January 2013 French military intervention in Mali. However, little guidance and means have been given so far to UN missions for dealing with such threats and implementing effective stabilization mandates. The High-Level Panel on Peace Operations, which recently released its report, noted that the usage of the term “stabilization” by the UN requires clarification. This article analyses the complex and evolving nature of threats in northern Mali and implications for MINUSMA and describes the military and political tools – including mediation – so far available within and outside the UN. The article concludes that the UN is bound to move towards stabilization when and if deployed in contexts such as Mali’s if it wants to remain relevant. However, such a move should be based on an overarching UN stabilization doctrine and context-specific UN-wide stabilization strategies which are first and foremost political

  14. Assessment of undiscovered oil and gas resources of the Taoudeni Basin Province, Mali and Mauritania, 2015

    Science.gov (United States)

    Brownfield, Michael E.; Schenk, Christopher J.; Klett, Timothy R.; Tennyson, Marilyn E.; Pitman, Janet K.; Gaswirth, Stephanie B.; Le, Phuong A.; Leathers-Miller, Heidi M.; Mercier, Tracey J.; Marra, Kristen R.; Hawkins, Sarah J.

    2016-03-31

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated undiscovered, technically recoverable mean resources of 160 million barrels of conventional oil, 1,880 billion cubic feet of conventional gas, 602 million barrels of shale oil, and 6,395 billion cubic feet of shale gas in the Taoudeni Basin Province in Mali and Mauritania.

  15. MalY of Escherichia coli is an enzyme with the activity of a beta C-S lyase (cystathionase).

    OpenAIRE

    Zdych, E; Peist, R; Reidl, J.; Boos, W

    1995-01-01

    The Escherichia coli maltose system consists of a number of genes whose products are involved in the uptake and metabolism of maltose and maltodextrins. MalT is the central positive gene activator of the regulon and is, together with the cyclic AMP-catabolite gene activator protein system, necessary for the expression of the maltose genes. Expression of malY, a MalT-independent gene, leads to the repression of all MalT-dependent genes. We have purified MalY to homogeneity and found it to be a...

  16. [Economics of health care in Mali].

    Science.gov (United States)

    Coulibaly, S O; Keita, M

    1996-01-01

    From the results obtained regarding the financing of health care in Mali, we emphasize two important points. First, there is a lack of criteria for the distribution of finding in the health care sector, resulting in a waste of resources. Secondly, there is an absence of adequate pharmaceutical policies. The field studies led in 1987 provided the following observations. The rate of occupation of the beds is very low. Also, the numerous new investments are not yet put into service because of the lack of necessary equipment of qualified personnel. In addition, this does not consider the excessive investments occurring in certain localities where neither the rate of frequentation nor the economic conditions will ever allow the use of the capacity created. Among the possible solutions for the crisis of health care funding in Mali, the following should be priority: first, to fight against the complete lack of organization of the activities at the health care centers; secondly, to fight against the waste and misappropriation of money resulting from the behavior of the medical and paramedical personnel: and thirdly, to clarify the management of the resources coming from the charges for each service. The pharmaceutical policies adopted and implemented in recent years Largely contributed to, first, the creation of competition between essential generic medications and nongeneric medications that can be replaced, and then, the destruction of the public network of drug distribution. These conditions considerably limited the distribution of essential medications; yet, this is the only manner of reducing the pharmaceutical expenses and accordingly, allowing more funding for other medical services. As the distribution network is disorganized, the only alternative for the population to obtain the medications at the lowest price was to create centers of purchasing and distribution and to multiply the number of retailers of essential medications. Extensive work has been conducted in

  17. Identification of Thai Hom Mali rice using a refractometer

    Science.gov (United States)

    Sumriddetchkajorn, Sarun; Suwansukho, Kajpanya; Buranasiri, Prathan

    2009-05-01

    Because Thai Hom Mali, also known as Thai Dawk Mali (KDML105), rice is very popular and its price is high compared to other Thai rice varieties, there is an increase in mixing KDML105 milled and unmilled rice grains with other rice varieties, leading to unqualified KDML105 milled rice products for export and unqualified KDML105 unmilled rice seeds for next plants. Instead of using traditional time- and energy- consuming procedures such as alkaline spreading value and pasting property tests, this paper proposes a fast refractometry-based method to analyze ground milled rice grains dissolved in an alkaline solution. Our idea comes from the fact that due to differences in the amount of amylose content in each rice variety, the refractive index of the milled rice powder dissolved in an alkaline solution can be used to distinguish the desired KDML105 rice from others. In our approach, only 0.1 grams of milled rice powder is ground, it is then dissolved in a 10% potassium hydroxide, and its refractive index is investigated. Our experiment using a temperature-controlled optical refractometer and four Thai rice varieties (KDML105, Pathumthani1, Chainat1, and a Thai sticky rice) shows that the milled KDML105 rice can be distinguished from the remaining three rice varieties with a total false error rate of 6.7% and the required measurement time of < 20 seconds. Key advantages include simplicity, moderate accuracy, and less waste produced.

  18. Mali - A Participatory Approach to Livestock Development

    OpenAIRE

    Metzel, Jeffrey; Menudier, N.

    1997-01-01

    The livestock sector in Mali accounts for 43 percent of cattle exports in the Sahel sub-region. However, while the sub-sector accounted for 28.6 percent of agriculture's contribution to Gross Domestic Product (GDP), investment in it amounted to only 10.7 percent of the total budget allocation to rural development. The African Financial Community (CFA) devaluation in January 1994 increased ...

  19. Cotton Production in Mali: Subsidies or Sustainable Development?

    Science.gov (United States)

    Moore, Lindsey

    2007-01-01

    Current trade rules concerning cotton subsidies are intricately linked with poverty and hunger in Mali. Over half of Mali's economy and over 30 million people depend directly on cotton. It is the main cash crop and the most important source of export revenue. Cotton also plays a key role in development policies and in the fight against poverty by…

  20. DNA sequence analysis of herbarium specimens facilitates the revival of Botrytis mali, a postharvest pathogen of apple.

    Science.gov (United States)

    O'Gorman, Daniel T; Sholberg, Peter L; Stokes, Sarah C; Ginns, J

    2008-01-01

    The fungus Botrytis cinerea has been widely accepted as the species responsible for causing gray mold decay of apple, although a second species causing apple decay, B. mali, was reported in 1931. Botrytis mali was validly published in 1931, nevertheless it has always been considered a doubtful species. To study the relationship of Botrytis isolates causing gray mold on apple, DNA sequence analysis was employed. Twenty-eight Botrytis isolates consisting of 10 species were sampled, including two B. mali herbarium specimens from apple originally deposited in 1932. The DNA sequence analysis of the beta-tubulin and glyceraldehyde-3-phosphate dehydrogenase (G3PDH) genes placed the isolates into groupings with defined species boundaries that generally reflected the morphologically based model for Botrytis classification. The B. cinerea isolates from apple and other host plants were placed in a single clade. The B. mali herbarium specimens however always fell well outside that clade. The DNA sequence analysis reported in this study support the initial work by Ruehle (1931) describing the apple pathogen B. mali as a unique species.

  1. Doing development with men: Some reflections on a case study from Mali

    OpenAIRE

    Harris, C.

    2006-01-01

    Metadata only record The paper presents reflection on gender-based power relations based on the author's fieldwork in Mali. The paper highlights the need to acknowledge that unequal power relations are multi-dimensional and complex. Harris' work shows Foucault's micro-mechanisms of power and of resistance; showing that women have more power than it is attributed to them, but since this power is not part of the public discourse this limits their ability to exercise power. Gender-based power...

  2. Et semester i Mali og Ghana

    DEFF Research Database (Denmark)

    Eskemose Andersen, Jørgen; Andreasen, Jørgen

    2007-01-01

    Et semesterkursus afholdes hvert andet år i Afrika med en gruppe studerende fra Kunstakademiets Arkitektskole. Kurset knytter sig til den forskning, som gennem flere år er udført af ansatte ved Department of Human Settlements (DHS). Kurset prioriterer udforskningens metoder og dialog med lokale b...... beboere og myndigheder. Kursets pædagogiske sigte er at konfrontere deltagerne med deres faglige felt i en radikalt anderledes kultur. Kurset indledes en måned i Mali med en indføring i metoder. Hovedstudiet er i Ghana med et ophold på 2½ måned i byen Kumasi....

  3. SWALLOWED FISH BONES IN MALI

    Directory of Open Access Journals (Sweden)

    Sacko HB

    2015-07-01

    Full Text Available Objective: To study the different aspects, clinical, diagnostic and therapeutic of 114 cases of fish bones in the upper digestive tract . Methods: One hundred fourteen patients with fish bones suspected in the upper digestive tract were admitted in our department between February 2010 and October 2012. Results: There was a predominance of the male: 66 men (58%. The average age of the patients was 26 years with extremes 3 to 62 years old. The tongue base and vallecula are constituted the principals locations 66.66%. In the majority of the cases the fish bones were removed by direct pharyngoscopy in 43.86 %. We have not notified any serious complications. Conclusion: Therefore this study shows the foreign fish bones are frequently just as well in children as adult. The fish bones are particularly lodged in tongue base. The classical methods of extraction are permit to remove the all foreign fish bones.

  4. Families in movement: transformation of the family in urban Mali, with a focus on intercontinental mobility

    OpenAIRE

    Barten, J.

    2009-01-01

    This Masters Thesis is the winner of the ASC's Africa Thesis Award 2008. It deals with changing family relations in African society in the context of intercontinental mobility. Based on many stories of migrants in both Mali and the Netherlands, the book reveals some of the negative sides of close family relations and the resulting everyday dilemmas for migrants. In doing so, the concept of family as used in social sciences is criticised, stressing the dynamics of global family practices and a...

  5. Anti-Money Laundering and Combating the Financing of Terrorism : Mali

    OpenAIRE

    World Bank, (WB)

    2008-01-01

    This assessment of the Anti-Money Laundering and Combating the Financing of Terrorism (AML-CFT) regime in Mali was conducted on the basis of the Forty Recommendations of 2003 and the Nine Special Recommendations on the financing of terrorism drawn up in 2003 and 2001, respectively, by the Financial Action Task Force (FATF), and on the AML-CFT Methodology of 2004. The assessment was based o...

  6. Assessing Community Readiness to Reduce Childhood Diarrheal Disease and Improve Food Security in Dioro, Mali.

    Science.gov (United States)

    Borresen, Erica C; Stone, Cordelia; Boré, Abdoulaye; Cissoko, Alima; Maiga, Ababacar; Koita, Ousmane A; Ryan, Elizabeth P

    2016-06-08

    Diarrhea and malnutrition represent leading causes of death for children in Mali. Understanding a community's needs and ideas are critical to ensure the success of prevention and treatment interventions for diarrheal disease, as well as to improve food security to help reduce malnutrition. The objective of this study was to incorporate the Community Readiness Model (CRM) for the issues of childhood diarrheal disease and food security in Mali to measure baseline community readiness prior to any program implementation. Thirteen key respondents residing in Dioro, Mali were selected based on varied social roles and demographics and completed two questionnaires on these public health issues. The overall readiness score to reduce childhood diarrheal disease was 5.75 ± 1.0 standard deviation (preparation stage). The overall readiness score to improve food security was 5.5 ± 0.5 standard deviation (preparation stage). The preparation stage indicates that at least some of the community have basic knowledge regarding these issues, and want to act locally to reduce childhood diarrhea and improve food security and nutrition. Proposed activities to increase community readiness on these issues are provided and are broad enough to allow opportunities to implement community- and culturally-specific activities by the Dioro community.

  7. Assessing Community Readiness to Reduce Childhood Diarrheal Disease and Improve Food Security in Dioro, Mali

    Directory of Open Access Journals (Sweden)

    Erica C. Borresen

    2016-06-01

    Full Text Available Diarrhea and malnutrition represent leading causes of death for children in Mali. Understanding a community’s needs and ideas are critical to ensure the success of prevention and treatment interventions for diarrheal disease, as well as to improve food security to help reduce malnutrition. The objective of this study was to incorporate the Community Readiness Model (CRM for the issues of childhood diarrheal disease and food security in Mali to measure baseline community readiness prior to any program implementation. Thirteen key respondents residing in Dioro, Mali were selected based on varied social roles and demographics and completed two questionnaires on these public health issues. The overall readiness score to reduce childhood diarrheal disease was 5.75 ± 1.0 standard deviation (preparation stage. The overall readiness score to improve food security was 5.5 ± 0.5 standard deviation (preparation stage. The preparation stage indicates that at least some of the community have basic knowledge regarding these issues, and want to act locally to reduce childhood diarrhea and improve food security and nutrition. Proposed activities to increase community readiness on these issues are provided and are broad enough to allow opportunities to implement community- and culturally-specific activities by the Dioro community.

  8. Assessing Community Readiness to Reduce Childhood Diarrheal Disease and Improve Food Security in Dioro, Mali.

    Science.gov (United States)

    Borresen, Erica C; Stone, Cordelia; Boré, Abdoulaye; Cissoko, Alima; Maiga, Ababacar; Koita, Ousmane A; Ryan, Elizabeth P

    2016-01-01

    Diarrhea and malnutrition represent leading causes of death for children in Mali. Understanding a community's needs and ideas are critical to ensure the success of prevention and treatment interventions for diarrheal disease, as well as to improve food security to help reduce malnutrition. The objective of this study was to incorporate the Community Readiness Model (CRM) for the issues of childhood diarrheal disease and food security in Mali to measure baseline community readiness prior to any program implementation. Thirteen key respondents residing in Dioro, Mali were selected based on varied social roles and demographics and completed two questionnaires on these public health issues. The overall readiness score to reduce childhood diarrheal disease was 5.75 ± 1.0 standard deviation (preparation stage). The overall readiness score to improve food security was 5.5 ± 0.5 standard deviation (preparation stage). The preparation stage indicates that at least some of the community have basic knowledge regarding these issues, and want to act locally to reduce childhood diarrhea and improve food security and nutrition. Proposed activities to increase community readiness on these issues are provided and are broad enough to allow opportunities to implement community- and culturally-specific activities by the Dioro community. PMID:27338428

  9. Can Community Health Workers Report Accurately on Births and Deaths? Results of Field Assessments in Ethiopia, Malawi and Mali.

    Directory of Open Access Journals (Sweden)

    Romesh Silva

    Full Text Available Most low-income countries lack complete and accurate vital registration systems. As a result, measures of under-five mortality rates rely mostly on household surveys. In collaboration with partners in Ethiopia, Ghana, Malawi, and Mali, we assessed the completeness and accuracy of reporting of births and deaths by community-based health workers, and the accuracy of annualized under-five mortality rate estimates derived from these data. Here we report on results from Ethiopia, Malawi and Mali.In all three countries, community health workers (CHWs were trained, equipped and supported to report pregnancies, births and deaths within defined geographic areas over a period of at least fifteen months. In-country institutions collected these data every month. At each study site, we administered a full birth history (FBH or full pregnancy history (FPH, to women of reproductive age via a census of households in Mali and via household surveys in Ethiopia and Malawi. Using these FBHs/FPHs as a validation data source, we assessed the completeness of the counts of births and deaths and the accuracy of under-five, infant, and neonatal mortality rates from the community-based method against the retrospective FBH/FPH for rolling twelve-month periods. For each method we calculated total cost, average annual cost per 1,000 population, and average cost per vital event reported.On average, CHWs submitted monthly vital event reports for over 95 percent of catchment areas in Ethiopia and Malawi, and for 100 percent of catchment areas in Mali. The completeness of vital events reporting by CHWs varied: we estimated that 30%-90% of annualized expected births (i.e. the number of births estimated using a FPH were documented by CHWs and 22%-91% of annualized expected under-five deaths were documented by CHWs. Resulting annualized under-five mortality rates based on the CHW vital events reporting were, on average, under-estimated by 28% in Ethiopia, 32% in Malawi, and 9% in

  10. Toxins Produced by Valsa mali var. mali and Their Relationship with Pathogenicity

    Directory of Open Access Journals (Sweden)

    Caixia Wang

    2014-03-01

    Full Text Available Valsa mali var. mali (Vmm, the causal agent of apple tree canker disease, produces various toxic compounds, including protocatechuic acid, p-hydroxybenzoic acid, p-hydroxyacetophenone, 3-(p-hydroxyphenylpropanoic acid and phloroglucinol. Here, we examined the relationship between toxin production and the pathogenicity of Vmm strains and determined their bioactivities in several assays, for further elucidating the pathogenesis mechanisms of Vmm and for developing new procedures to control this disease. The toxins were quantified with the high performance liquid chromatography (HPLC method, and the results showed that the strain with attenuated virulence produced low levels of toxins with only three to four kinds of compounds being detectable. In contrast, higher amounts of toxins were produced by the more aggressive strain, and all five compounds were detected. This indicated a significant correlation between the pathogenicity of Vmm strains and their ability to produce toxins. However, this correlation only existed in planta, but not in vitro. During the infection of Vmm, protocatechuic acid was first detected at three days post inoculation (dpi, and the others at seven or 11 dpi. In addition, all compounds produced noticeable symptoms on host plants at concentrations of 2.5 to 40 mmol/L, with protocatechuic acid being the most effective compound, whereas 3-(p-hydroxyphenylpropanoic acid or p-hydroxybenzoic acid were the most active compounds on non-host plants.

  11. The match between motivation and performance management of health sector workers in Mali

    Directory of Open Access Journals (Sweden)

    Touré Hamadassalia

    2006-02-01

    Full Text Available Abstract Human resources for health (HRH play a central role in improving accessibility to services and quality of care. Their motivation influences this. In Mali, operational research was conducted to identify the match between motivation and the range and use of performance management activities. Objectives To describe the factors motivating and demotivating health workers in Mali and match the motivators with the implementation of performance management. Methods First an exploratory qualitative study was conducted: 28 interviews and eight group discussions were held. This was followed by a cross-sectional survey, during which 370 health workers were interviewed. The study population consisted of health workers of eight professional groups. The following issues were investigated: • motivating and demotivating factors; • experiences with performance management, including: job descriptions, continuous education, supervision, performance appraisal and career development. Findings The study showed that the main motivators of health workers were related to responsibility, training and recognition, next to salary. These can be influenced by performance management (job descriptions, supervisions, continuous education and performance appraisal. Performance management is not optimally implemented in Mali, as job descriptions were not present or were inappropriate; only 13% of interviewees received 4× per year supervision, and training needs were not analysed. Some 48% of the interviewees knew their performance had been appraised in the last two years; the appraisals were perceived as subjective. No other methods were in place to show recognition. The results enabled the research team to propose adaptations or improvements upon existing performance management. Conclusion The results showed the importance of adapting or improving upon performance management strategies to influence staff motivation. This can be done by matching performance management

  12. Sahelian pathways. Climate and society in Central and South Mali

    NARCIS (Netherlands)

    Bruijn, de M.E.; Kaag, M.A.A.; Til, van A.; Dijk, van J.W.M.

    2005-01-01

    Climate change is a global problem with local consequences. However, the direction and magnitude of these consequences in extremely vulnerable regions - such as the Sahel - cannot yet be predicted with any certainty. The studies in this volume focus on people for whom climate variability, mainly rai

  13. Refining Approximating Betweenness Centrality Based on Samplings

    CERN Document Server

    Ji, Shiyu

    2016-01-01

    Betweenness Centrality (BC) is an important measure used widely in complex network analysis, such as social network, web page search, etc. Computing the exact BC values is highly time consuming. Currently the fastest exact BC determining algorithm is given by Brandes, taking $O(nm)$ time for unweighted graphs and $O(nm+n^2\\log n)$ time for weighted graphs, where $n$ is the number of vertices and $m$ is the number of edges in the graph. Due to the extreme difficulty of reducing the time complexity of exact BC determining problem, many researchers have considered the possibility of any satisfactory BC approximation algorithms, especially those based on samplings. Bader et al. give the currently best BC approximation algorithm, with a high probability to successfully estimate the BC of one vertex within a factor of $1/\\varepsilon$ using $\\varepsilon t$ samples, where $t$ is the ratio between $n^2$ and the BC value of the vertex. However, some of the algorithmic parameters in Bader's work are not yet tightly boun...

  14. Mushroom host influence on Lycoriella mali (Diptera: Sciaridae) life cycle.

    Science.gov (United States)

    O'Connor, L; Keil, C B

    2005-04-01

    Lycoriella mali Fitch (Diptera: Sciaridae) infests mushroom crops early in the crop cycle. Recent observations in mushroom houses indicated a difference in emergence time and size of adult L. mali developing on various strains of commercial mushrooms. Samples of adult flies from isolated mushroom houses growing Portabella mushrooms were significantly heavier then those from oyster mushroom houses, whereas flies from shiitake mushroom houses were lightest in weight. Flies collected from isolated Portabella mushroom houses were reared on four strains and species of Agaricus and Pleurotus mushrooms. After the adults emerged, females were weighed, mated, and allowed to oviposit. The number of eggs laid increased as the weight of the female increased. Flies collected from isolated Portabella mushroom houses were reared on eight strains and species of mushrooms. Flies were reared for four generations on each host mushroom mycelium then switched to different host mushrooms. Overall, the hybrid strain of Agaricus bisporus (Lange) Imbach (Agaricales: Agaricomycetideae) was the most favorable host for L. mali, whereas the wild strain of A. bisporus was the least favorable host. Mushroom hosts influence developmental time, survivorship, weight, and reproduction of L. mali. PMID:15889722

  15. A grammar of Tadaksahak a northern Songhay language of Mali

    NARCIS (Netherlands)

    Christiansen-Bolli, Regula

    2010-01-01

    This dissertation is a descriptive grammar of the language Tadaksahak spoken by about 30,000 people living in the most eastern part of Mali. The four chapters of the book give 1. Information about the background of the group. 2. The phonological features of the language with the inventory of the pho

  16. Mali - amelioration de I'apprentissage dans les ecoles publques

    OpenAIRE

    Mohan, P. C.

    2004-01-01

    The overall objective of this Learning and Innovation Credit (2000-2003: US$3.8 million) was to further develop and assess the merits of bilingual education in Mali, in terms of financial and educational sustainability. The project was designed at a time when the education system was facing the following problems: (i) low enrollments, including gender and regional imbalances; (ii) poor lea...

  17. Diversification of Educational Provision and School-to-Work Transitions in Rural Mali: Analysing a Reconfiguration of Inequalities in Light of Justice Theories

    Science.gov (United States)

    Weyer, Frederique

    2011-01-01

    Based on an approach focusing on actors and in particular on educational trajectories, this paper analyses the effects of diversification of educational provision on inequalities in rural Mali. It shows that there are considerable gaps in the skills acquired by students, including within formal education. These gaps are perceived as illegitimate…

  18. Double Pyramidal Central Configurations with a Concave Quadrilateral Base

    Institute of Scientific and Technical Information of China (English)

    LIUXuefei

    2002-01-01

    As for a doudle pyramidal central configuration in 6-body problems,the case when its bese is a concave polygon is studied.By advancing several assumptions according to the definition of double pyramidal central configuration and deducing two theorems and two corollaries on this subject,the essential and sufficient conditions to form a double pyramidal central configuration with a concave quadriateral base are demonstrated.

  19. "Was it a mistake to tell others that you are infected with HIV?": factors associated with regret following HIV disclosure among people living with HIV in five countries (Mali, Morocco, Democratic Republic of the Congo, Ecuador and Romania). Results from a community-based research.

    Science.gov (United States)

    Henry, Emilie; Bernier, Adeline; Lazar, Florin; Matamba, Gaspard; Loukid, Mohamed; Bonifaz, Cesar; Diop, Samba; Otis, Joanne; Préau, Marie

    2015-02-01

    This study examined regret following HIV serostatus disclosure and associated factors in under-investigated contexts (Mali, Morocco, Democratic Republic of the Congo, Ecuador and Romania). A community-based cross-sectional study was implemented by a mixed consortium [researchers/community-based organizations (CBO)]. Trained CBO members interviewed 1,500 PLHIV in contact with CBOs using a 125-item questionnaire. A weighted multivariate logistic regression was performed. Among the 1,212 participants included in the analysis, 290 (23.9 %) declared that disclosure was a mistake. Female gender, percentage of PLHIV's network knowing about one's seropositivity from a third party, having suffered rejection after disclosure, having suffered HIV-based discrimination at work, perceived seriousness of infection score, daily loneliness, property index and self-esteem score were independently associated with regret. Discrimination, as well as individual characteristics and skills may affect the disclosure experience. Interventions aiming at improving PLHIV skills and reducing their social isolation may facilitate the disclosure process and avoid negative consequences. PMID:25533922

  20. "Was it a mistake to tell others that you are infected with HIV?": factors associated with regret following HIV disclosure among people living with HIV in five countries (Mali, Morocco, Democratic Republic of the Congo, Ecuador and Romania). Results from a community-based research.

    Science.gov (United States)

    Henry, Emilie; Bernier, Adeline; Lazar, Florin; Matamba, Gaspard; Loukid, Mohamed; Bonifaz, Cesar; Diop, Samba; Otis, Joanne; Préau, Marie

    2015-02-01

    This study examined regret following HIV serostatus disclosure and associated factors in under-investigated contexts (Mali, Morocco, Democratic Republic of the Congo, Ecuador and Romania). A community-based cross-sectional study was implemented by a mixed consortium [researchers/community-based organizations (CBO)]. Trained CBO members interviewed 1,500 PLHIV in contact with CBOs using a 125-item questionnaire. A weighted multivariate logistic regression was performed. Among the 1,212 participants included in the analysis, 290 (23.9 %) declared that disclosure was a mistake. Female gender, percentage of PLHIV's network knowing about one's seropositivity from a third party, having suffered rejection after disclosure, having suffered HIV-based discrimination at work, perceived seriousness of infection score, daily loneliness, property index and self-esteem score were independently associated with regret. Discrimination, as well as individual characteristics and skills may affect the disclosure experience. Interventions aiming at improving PLHIV skills and reducing their social isolation may facilitate the disclosure process and avoid negative consequences.

  1. Central Tracking Detector Based on Scintillating Fibres

    CERN Multimedia

    2002-01-01

    Scintillating fibres form a reasonable compromise for central tracking detectors in terms of price, resolution, response time, occupancy and heat production. \\\\ \\\\ New fluorescents with large Stokes shifts have been produced, capable of working without wavelength shifters. Coherent multibundles have been developed to achieve high packing fractions. Small segments of tracker shell have been assembled and beam tests have confirmed expectations on spatial resolution. An opto-electronic delay line has been designed to delay the track patterns and enable coincidences with a first level trigger. Replacement of the conventional phosphor screen anode with a Si pixel chip is achieved. This tube is called ISPA-tube and has already been operated in beam tests with a scintillating fibres tracker. \\\\ \\\\ The aim of the proposal is to improve hit densities for small diameter fibres by increasing the fraction of trapped light, by reducing absorption and reflection losses, by reflecting light at the free fibre end, and by inc...

  2. Devolution and human resources in primary healthcare in rural Mali.

    Science.gov (United States)

    Lodenstein, Elsbet; Dao, Dramane

    2011-06-08

    Devolution, as other types of decentralization (e.g. deconcentration, delegation, privatization), profoundly changes governance relations in the health system. Devolution is meant to affect performance of the health system by transferring responsibilities and authority to locally elected governments. The key question of this article is: what does devolution mean for human resources for health in Mali?This article assesses the key advantages and dilemmas associated with devolution such as responsiveness to local needs, downward accountability and health worker retention. Challenges of politics and capacities are also addressed in relation to human resources for health at the local level. Examples are derived from experiences in Mali with a capacity development programme and from case studies of other countries. It is not research findings that are presented, but highlights of key issues at stake aimed at inspiring the debate in Mali and elsewhere.A first lesson from the discussion suggests that in the context of human resources for health, decentralization of authority and resources is not the main issue. The challenge is to develop or strengthen accountability of those who decide and act, whether they are local politicians, bureaucrats or community representatives. If decentralization policies do not address public accountability, they will not fundamentally change human resource management, quality and equity of staffing. A second lesson is that successful devolution requires innovations in capacity development of all actors involved and in designing effective incentive measures. A final key conclusion is that the topic of devolution policy and its effects on human resources for health, and vice versa, merit more attention. A better understanding may lead to more appropriate policy designs and better preparation for the actors involved in countries that are embarking on decentralization, as is the case in Mali.

  3. Devolution and human resources in primary healthcare in rural Mali

    Directory of Open Access Journals (Sweden)

    Dao Dramane

    2011-06-01

    Full Text Available Abstract Devolution, as other types of decentralization (e.g. deconcentration, delegation, privatization, profoundly changes governance relations in the health system. Devolution is meant to affect performance of the health system by transferring responsibilities and authority to locally elected governments. The key question of this article is: what does devolution mean for human resources for health in Mali? This article assesses the key advantages and dilemmas associated with devolution such as responsiveness to local needs, downward accountability and health worker retention. Challenges of politics and capacities are also addressed in relation to human resources for health at the local level. Examples are derived from experiences in Mali with a capacity development programme and from case studies of other countries. It is not research findings that are presented, but highlights of key issues at stake aimed at inspiring the debate in Mali and elsewhere. A first lesson from the discussion suggests that in the context of human resources for health, decentralization of authority and resources is not the main issue. The challenge is to develop or strengthen accountability of those who decide and act, whether they are local politicians, bureaucrats or community representatives. If decentralization policies do not address public accountability, they will not fundamentally change human resource management, quality and equity of staffing. A second lesson is that successful devolution requires innovations in capacity development of all actors involved and in designing effective incentive measures. A final key conclusion is that the topic of devolution policy and its effects on human resources for health, and vice versa, merit more attention. A better understanding may lead to more appropriate policy designs and better preparation for the actors involved in countries that are embarking on decentralization, as is the case in Mali.

  4. Mali; Staff Report for the 2003 Article IV Consultation

    OpenAIRE

    International Monetary Fund

    2004-01-01

    Mali has been implementing reforms supported by the IMF through the Enhanced Structural Adjustment Facility (ESAF) and Poverty Reduction and Growth Facility (PRGF) arrangements. Executive Directors commended the macroeconomic management, poverty reduction, and structural reforms, and emphasized the need for strengthening fiscal performance, the finance system, and the effectiveness of the Anti-Money Laundering and Combating Financing of Terrorism regime. They agreed that the ex post assessmen...

  5. Eigenvector-Based Centrality Measures for Temporal Networks

    CERN Document Server

    Taylor, Dane; Clauset, Aaron; Porter, Mason A; Mucha, Peter J

    2015-01-01

    In the study of static networks, numerous "centrality" measures have been developed to quantify the importances of nodes in networks, and one can express many of these measures in terms of the leading eigenvector of a matrix. With the increasing availability of network data that changes in time, it is important to extend eigenvector-based centrality measures to time-dependent networks. In this paper, we introduce a principled generalization that is valid for any eigenvector-based centrality measure in terms of matrices of size $NT\\times NT$, where the components of the dominant eigenvector of such a matrix describes the centralities of $N$ nodes during $T$ time layers. Our approach relies on coupling centrality values between neighboring time layers with a inter-layer edge, whose weight controls the extent to which centrality trajectories change over time. By studying the limit of strong coupling between layers, we derive expressions for "time-averaged centralities," which are given by the zeroth-order terms ...

  6. Flood forests of the inner Niger delta, mali; past, present, and future

    NARCIS (Netherlands)

    Beintema, A.J.; Fofana, B.; Faye, A.; Huiskes, H.P.J.

    2005-01-01

    Flood forests have a special place in the Inner Niger Delta, Mali. They have a great economic value for the local populations, and are hotspots of biodiversity in the delta. This report reviews the status of all flood forests in the Inner Niger Delta, Mali, that are presently known, or have been kno

  7. Central skull base lymphoma in children: MR and CT features

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Hei-Kyung [Seoul National University College of Medicine, Department of Radiology, Seoul (Korea); Cheon, Jung-Eun; Kim, In-One; Youn, Byung Jae; Jung, Ah Young; Shin, Su-Mi; Kim, Woo Sun; Yeon, Kyung Mo [Seoul National University College of Medicine, Department of Radiology, Seoul (Korea); Seoul National University Hospital, Institute of Radiation Medicine, SNUMRC (Seoul National University Medical Research Center), Seoul (Korea)

    2008-08-15

    Central skull base tumours are rare in children. To characterize the imaging features of central skull base lymphoma in children to aid its diagnosis. The authors reviewed the CT findings (available in three patients) and MR findings (available in four patients) in four patients (three boys, one girl; age 2-12 years) with pathologically proven lymphoma (two with Burkitt lymphoma, two with B-cell lymphoma) involving the central skull base. Tumour location and extent, MRI signal intensities, noncontrast CT attenuation, patterns of enhancement, and changes in adjacent structures were evaluated. All four tumours involved the sphenoid bone. In three patients, the tumour extended to the ethmoid sinus and both cavernous sinuses. All lesions were isointense solid masses on T2-weighted images and showed avid enhancement, except for one lesion with a focal necrosis. All tumours were associated with adjacent dural thickening. Non-contrast CT showed highly attenuating masses and permeative bone destruction in the central skull base. Lymphoma involving the central skull base in children is visualized as an isointense mass on T2-weighted MRI with marked contrast enhancement and adjacent dural thickening, and as a highly attenuating mass on noncontrast CT with permeative or erosive bone destruction patterns. (orig.)

  8. Epidemiological survey of contagious bovine pleuropneumonia (CBPP) in Mali

    International Nuclear Information System (INIS)

    Full text: Mali is a major producer of livestock, which plays a predominant role in the economy of the country. It brings about 10% of the GDP, 15% of export incomes and constitutes the main source of incomes for the 30% of the national population. Now that rinderpest is controlled, contagious bovine pleuropneumonia (CBPP) remains the most important infectious disease of cattle not only in Mali, but in most tropical African countries causing great economic losses including mortality, loss of weight, reduced working ability, reduced fertility and indirect costs due to control programs. The disease is characterized by a severe fibrinous exudative pleuropneumonia and is caused by Mycoplasma mycoides subsp. mycoides SC (MmmCS). It is considered a priority disease by the Office of International Epizootie (OIE), the Pan-African Program for the control of epizootics (PACE) and the FAO-Emergency Prevention System for Transboundary Animal Diseases (FAOEMPRES). All these Institutions have recognized that the lack of information concerning the prevalence and the economic impact of the disease is an obstacle to implement any efficient program for its control in Africa. Therefore, research must be conducted in order to generate accurate data on the incidence and distribution of the disease before any appropriate coordinated control program can be defined for this continent. The present epidemiological study was conducted with the aim of studying the seroprevalence of the disease among cattle in Mali, its geographical distribution and its economical impacts. Serum samples collected from 8000 cattle in different parts of the country were tested for MmmSC specific antibody by the competitive ELISA (c-ELISA) and the complement fixation test (CFT). In parallel, data of CBPP cases for the past 10 years and the economic impact of the disease, including production losses and control costs were evaluated. The preliminary results of this study will be presented here. (author)

  9. Les fils textuels des violences familiales au Mali

    OpenAIRE

    Le Potvin, Sébastien

    2008-01-01

    Dans cet article, une analyse est faite des expressions de la violence dans les œuvres littéraires modernes du Mali. Par le biais de ces ouvrages, on a connaissance d’une forme de perception locale de la violence sociale qui est aussi la perception subjective de l’auteur. Les interprétations de la violence rejoignent celles du peuple qu’elles veulent représenter : les sans‑voix, les sans‑pouvoir.  L’analyse de la littérature moderne malienne montre que les actes de violence domestique accompa...

  10. Cancers du sein (féminin) et du foie en Afrique de l’Ouest : évolution temporelle de l’incidence et évaluation des facteurs de risque en Gambie et au Mali

    OpenAIRE

    Sighoko Mawadzoue, Frida Dominique

    2011-01-01

    In Sub-Saharan Africa, the exact burden of cancer remains largely unknown and understudied. The Gambia and Mali are among the few African countries with operational population-based cancer registries. Data from 1988 to 2006 for the Gambia and from 1987 to 2009 for Bamako-Mali were used to analyze the incidence rates according to age, sex and ethnicity and to characterize the profile of women with breast and liver cancers. The data were arbitrarily divided into two periods, 1988-1997 and 1998-...

  11. [Doctoral thesis: Demographic growth and economic and social development in Mali].

    Science.gov (United States)

    Dabo, K

    1999-12-01

    A doctoral thesis is described analyzing the relationships between demographic growth and economic and social development in Mali. The hypothesis is stated that demographic growth impedes economic development and any improvement in populations¿ standards of living. The hypothesis was verified using data for the period from 1960 to the present. Over that period, Mali conducted two general population censuses in 1976 and 1987, as well as several demographic research studies. The thesis is comprised of 4 parts, of which the first generally describes Mali. The second part analyzes the relationship between population growth and economic and social development in Mali. Study results are presented, followed by an analysis of the effects of economic and social development upon population growth in Mali through factors such as urbanization, education level, literacy, income, employment, occupation, gross domestic or gross national product by inhabitant, infant mortality rate, life expectancy at birth, contraceptive practice, fertility opinions and desires, women¿s status, and migration in Mali. Analysis indicates that Mali has not completely begun its demographic transition, but that traditional pronatalist behaviors are changing. Population policies and programs are explored in the third part of the thesis, followed by the fourth part which focuses upon methodological questions. PMID:12296197

  12. [Plasma selenium and peripartum cardiomyopathy in Bamako, Mali].

    Science.gov (United States)

    Cénac, A; Touré, K; Diarra, M B; Sergeant, C; Jobic, Y; Sanogo, K; Dembele, M; Fayol, V; Simonoff, M

    2004-01-01

    Peripartum heart failure due to unexplained dilated cardiomyopathy is a common disorder as Savannak-Sahelian Africa. One of the many suspected risk factors identified is selenium deficiency. The purpose of this study was to measure plasma selenium levels in patients with peripartum heart failure due to cardiomyopathy in Bamako, Republic of Mali and compare data with healthy Sahalian women with the same obstetrical status. Plasma selenium was measured in a patient group consisting of 28 Malian women presenting peripartum heart failure and in a control group of 28 healthy breast-feeding Nigerien women of comparable age. The criteria for matching the two groups was parity (similar number of deliveries) since multiparity is a risk factor for peripartum cardiomyopathy. The Wilcoxon test (nonparametric) was used to compare the 2 groups considering up value < 0.05 as significant. Plasma selenium was significantly lower in patients from Mali than in controls from Niger (65 +/- 17 ng/ml vs. 78 +/- 17 ng/ml, p = 0.01). The results of this study showing lower plasma selenium in Bamako patients with peripartum cardiomyopathy than in a matching healthy control population confirms the previous data from the Niamey study. PMID:15460143

  13. Photovoltaic energy in Mali. Technical and organisational challenges of solar solutions deployment

    International Nuclear Information System (INIS)

    In 2008, electricity access rate in rural Mali was below 11%. In view of the challenges of electrification and development of rural areas in Mali, solar energy is seen as a strategic technology. The SIDI has asked ENEA to work on the technical and organisational terms ensuring sustainable access and spreading of photovoltaic systems in rural Mali. As such, in this report, ENEA improves the knowledge of the sector's private actors, suggests support architectures tackling the problematic, and highlights critical points by market segments

  14. Surveillance of Food- and Smear-Transmitted Pathogens in European Soldiers with Diarrhea on Deployment in the Tropics: Experience from the European Union Training Mission (EUTM) Mali

    OpenAIRE

    Hagen Frickmann; Philipp Warnke; Claudia Frey; Salvatore Schmidt; Christian Janke; Kay Erkens; Ulrich Schotte; Thomas Köller; Winfried Maaßen; Andreas Podbielski; Alfred Binder; Rebecca Hinz; Benjamin Queyriaux; Dorothea Wiemer; Norbert Georg Schwarz

    2015-01-01

    Introduction. Since 2013, European soldiers have been deployed on the European Union Training Mission (EUTM) in Mali. From the beginning, diarrhea has been among the most “urgent” concerns. Diarrhea surveillance based on deployable real-time PCR equipment was conducted between December 2013 and August 2014. Material and Methods. In total, 53 stool samples were obtained from 51 soldiers with acute diarrhea. Multiplex PCR panels comprised enteroinvasive bacteria, diarrhea-associated Escherichia...

  15. Medical and economic benefits of telehealth in low- and middle-income countries: results of a study in four district hospitals in Mali

    OpenAIRE

    Bagayoko, Cheick Oumar; Traoré, Diakaridia; Thevoz, Laurence; Diabaté, Soumahila; Pecoul, David; Niang, Mahamoudane; Bediang, Georges Wylfred; Traoré, Seydou Tidiane; Anne, Abdrahamane; Geissbuhler, Antoine

    2014-01-01

    Background The aim of this study was to evaluate the impact of telehealth on 1) the diagnosis, and management in obstetrics and cardiology, 2) health care costs from patients’ perspectives, 3) attendance at health centres located in remote areas of Mali. Methods The impact of telehealth on health care utilization, quality, and costs was assessed using a five-point Likert-scale based questionnaire consisting of three dimensions. It was completed by health care professionals in four district ho...

  16. Sharing the recurrent costs of rural water supply in Mali : the role of WaterAid in promoting sustainable service delivery

    OpenAIRE

    Jones, Stephen

    2013-01-01

    This thesis analyses how and why the recurrent costs of water services are shared between different actors in the rural local government areas in Mali which are supported by the international NGO WaterAid. This analysis of the financing arrangements for rural water services is used to critically assess theory, policy and practice in three areas: the community-based management approach to service delivery, the role of decentralised local governments in supporting community management, and the ...

  17. A climate trend analysis of Mali

    Science.gov (United States)

    Funk, Christopher C.; Rowland, Jim; Adoum, Alkhalil; Eilerts, Gary; White, Libby

    2012-01-01

    This brief report, drawing from a multi-year effort by the U.S. Agency for International Development (USAID) Famine Early Warning Systems Network (FEWS NET), identifies modest declines in rainfall, accompanied by increases in air temperatures. These analyses are based on quality-controlled station observations. Conclusions: * Summer rains have remained relatively steady for the past 20 years, but are 12 percent below the 1920-1969 average. * Temperatures have increased by 0.8° Celsius since 1975, amplifying the effect of droughts. * Cereal yields are low but have been improving. * Current population and agricultural trends indicate that increased yields have offset population expansion, keeping per capita cereal production steady.

  18. The first case of Lassa fever imported from Mali to the United Kingdom, February 2009.

    Science.gov (United States)

    Atkin, S; Anaraki, S; Gothard, P; Walsh, A; Brown, D; Gopal, R; Hand, J; Morgan, D

    2009-03-12

    This is the first case of Lassa fever to be imported from Mali to the United Kingdom. This paper discusses the investigations, the virological analysis, the surveillance and management of contacts undertaken following a case of Lassa fever. PMID:19317988

  19. Agricultural climate change impact: General concerns and findings from Mali, Kenya, Uganda, and Senegal

    OpenAIRE

    Butt, T.; Angerer, J; Dyke, P.; Kim, M.; Kaitho, R.; Stuth, J.

    2004-01-01

    This paper discusses concerns about the impact of climate change on agriculture. Methods for assessing the impacts of climate change and the results from impact assessments in Mali, Kenya, Uganda, and Senegal are presented.

  20. In Vivo Efficacy and Parasite Clearance of Artesunate + Sulfadoxine-Pyrimethamine Versus Artemether-Lumefantrine in Mali.

    Science.gov (United States)

    Niaré, Karamoko; Dara, Antoine; Sagara, Issaka; Sissoko, Mahamadou S; Guindo, Cheick Oumar; Cissé, Nana H; Coulibaly, Cheick Oumar; Ringwald, Pascal; Benoit-Vical, Françoise; Berry, Antoine; Djimdé, Abdoulaye A; Doumbo, Ogobara K

    2016-03-01

    Although artemisinin resistance has yet to be reported in Africa, surveillance of the efficacy of artemisinin-based combination therapies (ACTs) is warranted. Here, the efficacy of artesunate + sulfadoxine-pyrimethamine (AS + SP) and artemether-lumefantrine (AL) was evaluated in Mali. Randomized open-label comparative in vivo assay of AS + SP versus AL were carried out using the 28-day follow-up World Health Organization protocol. Patients with uncomplicated falciparum malaria and at least 6 months of age were recruited between October 2010 and January 2014. A subset of these patients was selected to measure Plasmodium falciparum clearance time. Polymerase chain reaction-corrected adequate clinical and parasitological responses were 100% for AS + SP and 98.2% for AL with no significant difference (P = 0.06). The reinfection rates were comparable (P = 0.63) with 8.0% for AS + SP and 12.6% for AL. Individuals under 8 years were more susceptible to treatment failure (relative risk = 1.9; 95% confidence interval = 1.2, 3.3). Median parasite clearance half-life was 1.7 hours (interquartile range [IQR] = 1.3-2.2) for AS + SP and 1.9 hours (IQR = 1.5-2.5) for AL with no statistically significant difference (P = 0.24). Efficacy of AS + SP and AL was high. This study provides baseline information on parasite clearance half-lives after ACT treatment, particularly AS + SP, in Mali. PMID:26811430

  1. Researches on Technique for the Control of Agrilus mali Matsumura in Xinjiang%新疆野苹果小吉丁虫防治试验

    Institute of Scientific and Technical Information of China (English)

    刘逸泠; 祝建波

    2015-01-01

    采用林间试验,在苹果小吉丁虫幼虫期对受害野苹果树进行不同施药方式和施药浓度的组合处理,探究16%虫线清乳油对野苹果小吉丁虫化学防治效果。试验结果表明,采用打孔注药和输液法施药方式在30 d后校正防效均达到90%以上;采用输液法及施药浓度为1倍稀释时,在整个防治期内校正防效均高于其它处理。对返青率进行比较分析时发现,对于野苹果树生长,最适合的施药浓度为2倍稀释。因此,在虫害防治前期采用1倍稀释浓度、防治后期采用2倍稀释浓度进行施药防治的效果较好。%In order to provide the basis for the comprehensive management to Agrilus mali pets,the control effect of 16%-worm clear-ance EC to Agrilus mali Matsumura,the biggest threaten to Malus sieversii forest protection.The effect of different application meth-ods and pesticide concentration on wild apple trees during the Agrilus mali Matsumura pupal stage was investigated based on 16%-worm clearance EC.The correction control effect of hole injection and transfusion were reached 90% or more after 30 days,when transfusion with 1 fold dilution,the correction control effect were higher than other treatments;the rate of reviving comparative analy-sis found that the most suitable pesticide concentration is 2 fold dilution.The tested fungicides on Agrilus mali Matsumura can play a good control effect.Considering the control effect on Agrilus mali Matsumura and the growing of wild apple trees,the dilution of 1 times to the prevention and later treatment by 2 times dilution.

  2. Cost analysis of an integrated disease surveillance and response system: case of Burkina Faso, Eritrea, and Mali

    Directory of Open Access Journals (Sweden)

    Touré Kandioura

    2009-01-01

    Full Text Available Abstract Background Communicable diseases are the leading causes of illness, deaths, and disability in sub-Saharan Africa. To address these threats, countries within the World Health Organization (WHO African region adopted a regional strategy called Integrated Disease Surveillance and Response (IDSR. This strategy calls for streamlining resources, tools, and approaches to better detect and respond to the region's priority communicable disease. The purpose of this study was to analyze the incremental costs of establishing and subsequently operating activities for detection and response to the priority diseases under the IDSR. Methods We collected cost data for IDSR activities at central, regional, district, and primary health care center levels from Burkina Faso, Eritrea, and Mali, countries where IDSR is being fully implemented. These cost data included personnel, transportation items, office consumable goods, media campaigns, laboratory and response materials and supplies, and annual depreciation of buildings, equipment, and vehicles. Results Over the period studied (2002–2005, the average cost to implement the IDSR program in Eritrea was $0.16 per capita, $0.04 in Burkina Faso and $0.02 in Mali. In each country, the mean annual cost of IDSR was dependent on the health structure level, ranging from $35,899 to $69,920 at the region level, $10,790 to $13,941 at the district level, and $1,181 to $1,240 at the primary health care center level. The proportions spent on each IDSR activity varied due to demand for special items (e.g., equipment, supplies, drugs and vaccines, service availability, distance, and the epidemiological profile of the country. Conclusion This study demonstrates that the IDSR strategy can be considered a low cost public health system although the benefits have yet to be quantified. These data can also be used in future studies of the cost-effectiveness of IDSR.

  3. Lassa virus isolates from Mali and the Ivory Coast represent an emerging fifth lineage.

    Science.gov (United States)

    Manning, John T; Forrester, Naomi; Paessler, Slobodan

    2015-01-01

    Previous imported cases of Lassa fever (LF) into the United Kingdom from the Ivory Coast and Mali, as well as the detection of Lassa virus (LASV) among the Mastomys natalensis population within Mali has led to the suggestion that the endemic area for LF is expanding. Initial phylogenetic analyses arrange isolates from Mali and the Ivory Coast separately from the classical lineage IV isolates taken from Sierra Leone, Guinea, and Liberia. The availability of full genome sequences continues to increase, allowing for a more complete phylogenetic comparison of the isolates from Mali and the Ivory Coast to the other existing isolates. In this study, we utilized a Bayesian approach to infer the demographic histories of each LASV isolate for which the full sequence was available. Our results indicate that the isolates from Mali and the Ivory Coast group separately from the isolates of lineage IV, comprising a distinct fifth lineage. The split between lineages IV and V is estimated to have occurred around 200-300 years ago, which coincides with the colonial period of West Africa.

  4. Lassa Virus Isolates from Mali and the Ivory Coast Represent an Emerging Fifth Lineage

    Directory of Open Access Journals (Sweden)

    John Tyler Manning

    2015-10-01

    Full Text Available Previous imported cases of Lassa fever into the United Kingdom from the Ivory Coast and Mali, as well as the detection of Lassa virus among the Mastomys natalensis population within Mali has led to the suggestion that the endemic area for Lassa fever is expanding. Initial phylogenetic analyses arrange isolates from Mali and the Ivory Coast separately from the classical lineage IV isolates taken from Sierra Leone, Guinea, and Liberia. The availability of full genome sequences continues to increase, allowing for a more complete phylogenetic comparison of the isolates from Mali and the Ivory Coast to the other existing isolates. In this study, we utilized a Bayesian approach to infer the demographic histories of each Lassa virus isolate for which the full sequence was available. Our results indicate that the isolates from Mali and the Ivory Coast group separately from the isolates of lineage IV, comprising a distinct fifth lineage. The split between lineages IV and V is estimated to have occurred around 200-300 years ago, which coincides with the colonial period of West Africa.

  5. Geographic distribution and genetic characterization of Lassa virus in sub-Saharan Mali.

    Directory of Open Access Journals (Sweden)

    David Safronetz

    Full Text Available Lassa fever is an acute viral illness characterized by multi-organ failure and hemorrhagic manifestations. Lassa fever is most frequently diagnosed in Nigeria, Sierra Leone, Liberia, and Guinea, although sporadic cases have been recorded in other West African countries, including Mali. The etiological agent of Lassa fever is Lassa virus (LASV, an Arenavirus which is maintained in nature and frequently transmitted to humans by Mastomys natalensis. The purpose of this study was to better define the geographic distribution of LASV-infected rodents in sub-Saharan Mali.Small mammals were live-trapped at various locations across Mali for the purpose of identifying potential zoonotic pathogens. Serological and molecular assays were employed and determined LASV infected rodents were exclusively found in the southern Mali near the border of Côte d'Ivoire. Overall, 19.4% of Mastomys natalensis sampled in this region had evidence of LASV infection, with prevalence rates for individual villages ranging from 0 to 52%. Full-length genomic sequences were determined using high throughput sequencing methodologies for LASV isolates generated from tissue samples of rodents collected in four villages and confirmed the phylogenetic clustering of Malian LASV with strain AV.The risk of human infections with LASV is greatest in villages in southern Mali. Lassa fever should be considered in the differential diagnosis for febrile individuals and appropriate diagnostic techniques need to be established to determine the incidence of infection and disease in these regions.

  6. Optimal profit of the parasitation by Aphelinus mali in an IPM complementary strategy for the control of Eriosoma lanigerum.

    Science.gov (United States)

    Goossens, D; Bangels, E; Belien, T; Schoevaerts, C; De Maeyer, L

    2011-01-01

    During summer the parasitoid Aphelinus mali may certainly reduce the infestation of woolly apple aphid (Eriosoma lanigerum), but studies on the single interaction rarely indicate sufficient biological control in the period May-June. In this period chemical control by spirotetramat or pirimicarb remains indispensable in order to anticipate on dense migration waves and subsequent colonization of extension shoots by E. lanigerum. The limited parasitation by A. mali around flowering is linked with a delayed emergence from diapause and with a slower reproduction rate than its host. In 2010 and 2011 the first adult flights monitored on yellow sticky traps corresponded perfectly with the currently used prediction models for A. mali. Further accurate monitoring all along the season enabled also to determine a well defined endo-parasitic phase of A. mali occurring after the small peak observed around flowering. During this endo-parasitic phase A. mali larvae reside inside their mummified host. Compounds with higher acute toxicity on A. mali adults, like chloronicotinyl insecticides (CNI's), are preferably positioned here. Selectivity in the time can then be claimed. Respecting this principle, the further parasitation potential of A. mali in summer is not hampered. Preservation of the first peak of flights of A. mali in the pre-flowering period is essential for an exponential flight increase. This is essential for the parasitation of E. lanigerum in summer, which constitutes a valuable complement in the integrated control strategy. PMID:22696953

  7. Existence and uniqueness for a class of double pyramidal central configurations with a concave pentagonal base

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Based on some necessary conditions for double pyramidal central configurations with a concave pentagonal base, for any given ratio of masses, the existence and uniqueness of a class of double pyramidal central configurations with a concave pentagonal base in 7-body problems are proved and the range of the ratio between radius and half-height is obtained, within which the 7 bodies involved form a central configuration or form uniquely a central configuration.

  8. Traditional medicine practitioners’ knowledge and views on treatment of pregnant women in three regions of Mali

    Science.gov (United States)

    2013-01-01

    Background Despite the widespread use of medicinal plants in Mali, knowledge about how traditional practitioners (TPs) treat pregnant and lactating women is lacking. Aim of the study The aim of this study was to investigate how traditional practitioners in Mali treat common diseases and ailments during pregnancy. Methods Data was collected through structured interviews of traditional practitioners in one urban (Bamako) and two rural areas (Siby and Dioila) in Mali. The TPs were interviewed about how they treat common diseases and ailments during pregnancy. They were also asked to name harmful plants in pregnancy and plants that could affect breast milk production. In addition, we asked about nine specific medicinal plants commonly used in Mali; Opilia amentacea (syn. Opilia celtidifolia), Ximenia americana, Cola cordifolia, Combretum glutinosum, Parkia biglobosa, Trichilia emetica, Combretum micranthum, Lippia chevalieri and Vepris heterophylla. Results A total of 72 traditional practitioners (64% women, age: 34 to 90 years) were interviewed during an eight week period October 2011 to December 2011. They treated between 1 and 30 pregnant women with medicinal plants per months. We found a relatively high consensus for treatment of pregnant women with common diseases and ailments like nausea and dermatitis. The highest informer consensus was found for the treatment of malaria during pregnancy. TPs generally recommended pregnant women to avoid medicinal plants with bitter tastes like stem and root bark of Khaya senegalensis and Opilia amentacea (syn. Opilia celtidifolia). TPs distinguished between oral (potentially unsafe) and dermal use (safe) of Opilia amentacea (syn. Opilia celtidifolia). Cola cordifolia was used to facilitate labor. Conclusion Experience and knowledge about treatment of pregnant women with medicinal plants was broad among the traditional practitioners in the three investigated regions in Mali. Collaborating with traditional practitioners on the

  9. Comparative morphological analysis of apple blister mite, Eriophyes mali Nal., a new pest in Serbia

    Directory of Open Access Journals (Sweden)

    Biljana Vidović

    2014-06-01

    Full Text Available The apple blister mite, Eriophyes mali Nalepa, 1926 (Acari: Prostigmata: Eriophyoidea, has been recently found in Serbia as a new pest of apple. The history of its research, the results of a morphological analysis and degree of infestation are presented. A comparison of the main morphological features of mites from different populations of remote geographical origin has shown that the apple blister mite from Serbia is most similar to another European population (Bulgarian [or Austrian?] while it differs from E. mali originating from the USA and New Zealand. The percentage of infestation varied from 1.6% to 87.6%, with an average of 22.4%.

  10. Monitoring for impact: Evaluating 20 years of soil and water conservation in southern Mali

    OpenAIRE

    Bodnar, F.

    2005-01-01

    A soil and water conservation (SWC) project has been going on in southern Mali since 1986. Donor support was gradually withdrawn between 1998 and 2002, but no final evaluation was undertaken to learn lessons from this long-term and large-scale experience. The objective of this present research was to find out how to evaluate impact, what the impact in Mali has been, and which recommendations could be made for monitoring and evaluation in SWC projects. A reconstructed logical framework made it...

  11. Lactase persistence genotypes and malaria susceptibility in Fulani of Mali

    Directory of Open Access Journals (Sweden)

    Dolo Amagana

    2011-01-01

    Full Text Available Abstract Background Fulani are a widely spread African ethnic group characterized by lower susceptibility to Plasmodium falciparum, clinical malaria morbidity and higher rate of lactase persistence compared to sympatric tribes. Lactase non-persistence, often called lactose intolerance, is the normal condition where lactase activity in the intestinal wall declines after weaning. Lactase persistence, common in Europe, and in certain African people with traditions of raising cattle, is caused by polymorphisms in the enhancer region approximately 14 kb upstream of the lactase gene. Methods To evaluate the relationship between malaria and lactase persistence genotypes, a 400 bp region surrounding the main European C/T-13910 polymorphism upstream of the lactase gene was sequenced. DNA samples used in the study originated from 162 Fulani and 79 Dogon individuals from Mali. Results Among 79 Dogon only one heterozygote of the lactase enhancer polymorphism was detected, whereas all others were homozygous for the ancestral C allele. Among the Fulani, the main European polymorphism at locus C/T-13910 was by far the most common polymorphism, with an allele frequency of 37%. Three other single-nucleotide polymorphisms were found with allele frequencies of 3.7%, 1.9% and 0.6% each. The novel DNA polymorphism T/C-13906 was seen in six heterozygous Fulani. Among the Fulani with lactase non-persistence CC genotypes at the C/T-13910 locus, 24% had malaria parasites detectable by microscopy compared to 18% for lactase persistent genotypes (P = 0.29. Pooling the lactase enhancer polymorphisms to a common presumptive genotype gave 28% microscopy positives for non-persistent and 17% for others (P = 0.11. Conclusions Plasmodium falciparum parasitaemia in asymptomatic Fulani is more common in individuals with lactase non-persistence genotypes, but this difference is not statistically significant. The potential immunoprotective properties of dietary cow milk as a reason

  12. [Utilisation of community health centres in Koulikoro region, Mali].

    Science.gov (United States)

    Sidibé, T; Sangho, H; Doumbia, S; Coulibaly, L; Kéïta, H D

    2008-01-01

    In Mali since the adoption of community health center (CSCOM) politics, their number knew a progression remarkable: 370 in 1998 and 660 in the end of 2003. Concerning the health staff, the ratio always remained per capita weak in relation to the international norms. In 2001 for the first level of health center, the quantum was: 1 physician for 14,612 inhabitants (norm being of 1/10,000); 1 nurse for 13,989 inhabitants (WHO norm being of 1/10,000). In spite of the well stocked efforts, the foreseen objectives are far from being reached. For example, the used rate of curative consultation was of 0.19 new contact/year/inhabitant. The foreseen objective is of 0.50. Our survey had as objectives to study the reasons of CSCOM's under frequenting, to identify the reasons and to propose some recommendations to improve the situation. We conducted a cross-sectional study that had taken place in Banamba and Dioïla in the Koulikoro's region in April 19 to May 8, 2004. Interview have been performed with the head of CSCOM, the CSCOM's staff, the persons responsible of community health association (ASACO), the mothers residing in the areas at least six months and having a child less than 5 years and the community leaders. We found that women in Banamba (89%) frequented the CSCOM more that those of Dioïla (60%). The reasons of the CSCOM's under frequenting are especially bound to the staff's instability, the geographical accessibility, to poverty and to the insufficiency of information. We recommend to the different actors to inform and to sensitize the population on the importance of the CSCOM's activities, to the state to take the staff's part in charge to improve their stability, in the ASACO to establish the contracts of work with the staff. PMID:19617149

  13. Fractal systems of central places based on intermittency of space-filling

    International Nuclear Information System (INIS)

    Highlights: → The idea of intermittency is introduced into central place model. → The revised central place model suggests incomplete space filling. → New central place fractals are presented for urban analysis. → The average nearest distance is proposed to estimate the fractal dimension. → The concept of distance-based space is replaced by that of dimension-based space. - Abstract: The central place models are fundamentally important in theoretical geography and city planning theory. The texture and structure of central place networks have been demonstrated to be self-similar in both theoretical and empirical studies. However, the underlying rationale of central place fractals in the real world has not yet been revealed so far. This paper is devoted to illustrating the mechanisms by which the fractal patterns can be generated from central place systems. The structural dimension of the traditional central place models is d = 2 indicating no intermittency in the spatial distribution of human settlements. This dimension value is inconsistent with empirical observations. Substituting the complete space filling with the incomplete space filling, we can obtain central place models with fractional dimension D < d = 2 indicative of spatial intermittency. Thus the conventional central place models are converted into fractal central place models. If we further integrate the chance factors into the improved central place fractals, the theory will be able to explain the real patterns of urban places very well. As empirical analyses, the US cities and towns are employed to verify the fractal-based models of central places.

  14. Mortality and Morbidity of Urban Road Traffic Crashes in Africa: Capture-Recapture Estimates in Bamako, Mali, 2012

    Science.gov (United States)

    Meda, Nicolas; Traoré, Mamadou S.; Staccini, Pascal

    2016-01-01

    Background Low- and middle-income countries are currently facing the massive public health challenge of road traffic injuries. The lack of effective surveillance systems hinders proper assessment of epidemiologic status and intervention priorities. The objective of our study was to estimate the mortality and morbidity attributable to road crashes in Bamako, Mali using the capture-recapture method. Methods During the 1 January, 2012–31 April, 2012 period, we collected data on road traffic crashes from the road accident registers of the police forces of Bamako, Mali on the one hand, and from a register kept by health facilities in the same area. An automatic, then manual matching procedure was performed to find pairs of records related to the same crash victims. The number of victims and the number of fatalities were estimated by the capture-recapture method using the Chapman estimator. Results The health facility and the police registries included 3587 and 1432 records, respectively. The matching procedure identified 603 common records, 31 of which were fatalities. The annual incidence estimate for road victims was 1038 in 100 000 and the annual incidence estimate for road fatalities was 12 in 100 000. Victims from both sources were more likely to be male, in the 15–34 age group, and almost half of all injured road users and two in three fatalities were using motorized two-wheelers. One victim out of five was a pedestrian. Conclusion Our estimates are in line with available literature data from low-income countries. While more cases were reported by health facilities than by police forces, we believe that an effective surveillance system should not be based solely on medical reports as much would be missing as regards the crash circumstances and characteristics. PMID:26871569

  15. Identification by PCR of non-typhoidal Salmonella enterica serovars associated with invasive infections among febrile patients in Mali.

    Directory of Open Access Journals (Sweden)

    Sharon M Tennant

    Full Text Available BACKGROUND: In sub-Saharan Africa, non-typhoidal Salmonella (NTS are emerging as a prominent cause of invasive disease (bacteremia and focal infections such as meningitis in infants and young children. Importantly, including data from Mali, three serovars, Salmonella enterica serovar Typhimurium, Salmonella Enteritidis and Salmonella Dublin, account for the majority of non-typhoidal Salmonella isolated from these patients. METHODS: We have extended a previously developed series of polymerase chain reactions (PCRs based on O serogrouping and H typing to identify Salmonella Typhimurium and variants (mostly I 4,[5],12:i:-, Salmonella Enteritidis and Salmonella Dublin. We also designed primers to detect Salmonella Stanleyville, a serovar found in West Africa. Another PCR was used to differentiate diphasic Salmonella Typhimurium and monophasic Salmonella Typhimurium from other O serogroup B, H:i serovars. We used these PCRs to blind-test 327 Salmonella serogroup B and D isolates that were obtained from the blood cultures of febrile patients in Bamako, Mali. PRINCIPAL FINDINGS: We have shown that when used in conjunction with our previously described O-serogrouping PCR, our PCRs are 100% sensitive and specific in identifying Salmonella Typhimurium and variants, Salmonella Enteritidis, Salmonella Dublin and Salmonella Stanleyville. When we attempted to differentiate 171 Salmonella Typhimurium (I 4,[ 5],12:i:1,2 strains from 52 monophasic Salmonella Typhimurium (I 4,[5],12:i:- strains, we were able to correctly identify 170 of the Salmonella Typhimurium and 51 of the Salmonella I 4,[5],12:i:- strains. CONCLUSION: We have described a simple yet effective PCR method to support surveillance of the incidence of invasive disease caused by NTS in developing countries.

  16. Organising trade : a practice-oriented analysis of cooperatives and networks trading cereals in South Mali

    NARCIS (Netherlands)

    Mangnus, E.P.M.

    2015-01-01

    Abstract Farmer organisations have become the centrepiece of pro-poor market development strategies in Africa. Assumed to facilitate scale, quality of produce and professionalism they are regarded as a solution for farmers that are hampered from economic opportunities. In Mali publ

  17. Olfactory response of the predator Zetzellia mali to a prey patch occupied by a conspecific predator

    NARCIS (Netherlands)

    A. Zahedi-Golpayegani; A. Saboori; M.W. Sabelis

    2007-01-01

    While searching for food, predators may use volatiles associated with their prey, but also with their competitors for prey. This was tested for the case of Zetzellia mali (Ewing) (Acari: Stigmaeidae), an important predator of the hawthorn spider mite, Amphitetranychus viennensis (Zacher) (Acari: Tet

  18. Clinical manifestations of Waardenburg syndrome in a male adolescent in Mali, West Africa.

    Science.gov (United States)

    Imperato, Pascal James; Imperato, Gavin H

    2015-02-01

    Waardenburg syndrome (WS) is a genetic disorder of which there are four distinct types. These four types are differentiated by the physical defects which they produce. Presented here is the case of a 13-year-old boy with WS Type I who was observed and physically assessed in Mali, West Africa in 1969. His physical findings included a bright blue coloring to the irises of the eyes, profound sensorineural deafness, mutism, dystopia canthorum (lateral displacement of the inner canthi of the eyes), broad nasal root, bushy eyebrows, and scaphoid deformities of the supraorbital portions of the frontal bone. Because family members were not available for interviews or physical examinations, it was not possible to determine if this patient was suffering from a congenital form of the disorder or from a spontaneous mutation. Given the patient's then location in a remote rural area of Mali where electricity was absent, it was not possible to perform additional diagnostic tests. The patient described here is the first with WS in Mali, West Africa to have been medically observed and evaluated and later documented in the medical literature. A second case of the syndrome in Mali was described in the medical literature in 2011 in an 18-month-old infant who did not have sensorineural hearing loss, but who did have a bilateral cleft lip. An historical overview of WS is presented along with details concerning the characteristics of the four types of the disorder. PMID:25224968

  19. Communicating war in Mali, 2012 : On-offline networked political agency in times of conflict

    NARCIS (Netherlands)

    Bruijn, de M.E.; Pelckmans, L.; Sangare, B.

    2015-01-01

    The Arab Spring raised high expectations for political freedom, especially for situations in which the rapid development of ICT intersects with political oppression and rebellion, as was the case in Mali, West Africa. In 2012 the country’s northern part fell into the hands of ‘rebels’ and jihadists

  20. Implementation of contour vegetation barriers under farmer conditions in Burkina Faso and Mali

    NARCIS (Netherlands)

    Spaan, W.P.; Bodnar, F.; Idoe, O.; Graaff, de J.

    2004-01-01

    Amongst the soil and water conservation (SWC) measures adopted in Burkina Faso and Mali, contour vegetation barriers (CVB) constitute a cheap option in terms of labour and material requirements. In order to understand the actual adoption and maintenance of CVB, labour requirements of five commonly a

  1. Factors influencing adoption of soil and water conservation measures in southern Mali

    NARCIS (Netherlands)

    Bodnar, F.; Graaff, de J.

    2003-01-01

    A soil and water conservation (SWC) extension programme, promoting erosion control measures and soil fertility measures, has been going on in southern Mali since 1986. Five factors that influence farmer adoption of SWC measures were analysed: land pressure, cotton-growing area, possession of ploughi

  2. Field evaluation of anthracnose resistance for sorghum germplasm from the Sikasso region in Mali

    Science.gov (United States)

    The USDA, ARS National Plant Germplasm System maintains 132 sorghum landraces from the Sikasso region of Mali. This germplasm was inoculated with Colletotrichum sublineolum and evaluated for foliar anthracnose resistance at the USDA, ARS Tropical Agriculture Research Station in Isabela, Puerto Rico...

  3. Evaluation of sorghum accessions from Ethiopia and Mali against Fusarium thapsinum

    Science.gov (United States)

    Thirty-eight sorghum accessions from Ethiopia and Mali along with resistant (Sureno and SC719) and susceptible (RTx430 and RTx2536) checks were evaluated in replicated plots for resistance against Fusarium thapsinum at Isabela, Puerto Rico. Environmental conditions such as temperature, relative hum...

  4. Understanding farm trajectories and development pathways: Two decades of change in southern Mali

    NARCIS (Netherlands)

    Falconnier, G.N.; Descheemaeker, K.K.E.; Mourik, van T.A.; Sanogo, O.; Giller, K.E.

    2015-01-01

    Institutional support for smallholders has been the motor for the expanding cotton production sector in southern Mali since the 1970s. Smallholder farms exhibit diverse resource endowments and little is known on how they benefit from and cope with changes in this institutional support. In this paper

  5. Meaningful Learning? Gendered Experiences with an NGO-Sponsored Literacy Program in Rural Mali

    Science.gov (United States)

    Fuhriman, Addie; Ballif-Spanvill, Bonnie; Ward, Carol; Solomon, Yodit; Widdison-Jones, Kacey

    2006-01-01

    This paper examines the effectiveness of an NGO-sponsored literacy program in rural Mali. The study employs ethnographic techniques to examine the type of literacy instruction provided, the level of participation, the meanings of literacy to participants, and the contextual factors that influence the social and personal effects of literacy. The…

  6. Effects of climate variability and climate change on crop production in southern Mali

    NARCIS (Netherlands)

    Traore, B.; Corbeels, M.; Wijk, van M.T.; Rufino, M.C.; Giller, K.E.

    2013-01-01

    In West Africa predictions of future changes in climate and especially rainfall are highly uncertain, and up to now no long-term analyses are available of the effects of climate on crop production. This study analyses long-term trends in climate variability at N'Tarla and Sikasso in southern Mali us

  7. Socioeconomic and Fiscal Impact of Large-Scale Gold Mining in Mali

    OpenAIRE

    Sanoh,Aly; Coulibaly, Massaoly

    2015-01-01

    This paper analyzes the socioeconomic, fiscal, and governance impact of gold mining in Mali. The analysis finds that, at the national level, mining plays an important role by contributing to export earnings and overall government fiscal revenue. In 2013, the mining sector represented 7 percent of gross domestic product, contributed 1.5 percent to growth in total gross domestic product, and...

  8. La rizipisciculture au Mali: Pratiques et perspectives de l'innovation piscicole

    Directory of Open Access Journals (Sweden)

    Niaré, T.

    2014-01-01

    Full Text Available Rice-Fish Culture in Mali: Practices and Prospects of Piscicultural Innovation. Mali is a country of fishing tradition in its rivers streams. Its fish production is the highest in West Africa, but it is dependent on the flood regime of Niger River. Fish farming appears to be a good alternative for increasing the amount of fish available during drought periods. A new fish production activity has progressively taken place in rural areas, i.e. "rizipisciculture" (rice-fish farming, since 2006. This emergent activity constitutes another challenge for agricultural research in Mali, actually raising up more questions than solutions. Individual surveys were conducted in the area of 'Office du Périmètre Irrigué de Baguinéda (OPIB', a rice extension service. Fifteen out of 23 farmers, so 65% of those practicing rizipisciculture, were surveyed and monitored in 2011. This investigation showed some disparities in the practices and the results of rice-fish production. Fish yield in the rice compartments varies between 408 and 438 kg.ha-1. This activity is facing environmental, socio-cultural, technic, institutional and financial constraints. In Mali, there is an important potential for irrigated rice production, which is favorable for the development of rice-fish farming. The sustainability of this new technology must however still be proved, and its socio-economic profitability demonstrated.

  9. The True Lion King of Africa: The Epic History of Sundiata, King of Old Mali.

    Science.gov (United States)

    Paterno, Domenica R.

    David Wisniewski's 1992 picture book version of the African epic of "Sundiata, Lion King of Mali" and the actual historical account of the 13th century Lion King, Sundiata, are both badly served by Disney's "The Lion King." Disney has been praised for using African animals as story characters; for using the African landscape as a story setting;…

  10. Consumption of, and beliefs about fonio (digitaria exilis) in urban area in Mali

    NARCIS (Netherlands)

    Fanou, N.; Koreissi, Y.; Dossa, R.A.M.; Brouwer, I.D.

    2009-01-01

    The study sought to determine beliefs and practices about neglected crops in West Africa, using fonio (Digitaria exilis) as a model to understand how obstacles impede the consumption of this cereal in Bamako, the capital city of Mali. This was a crosssectional study on food ethnography in three step

  11. [A Dutchman from Mali with a perianal ulcer caused by cutaneous amoebiasis

    NARCIS (Netherlands)

    Kroft, I.; Warris, A.; Jansen, L.E.; Crevel, R. van

    2005-01-01

    A 66-year-old Dutchman, living in Mali, presented with an extensive progressive perianal ulcer despite local and antibiotic treatment. Microscopic examination of the stool revealed Entamoeba histolytica/dispar cysts and phagocytosing trophozoites were seen in fresh scrapings of the ulcer, a diagnost

  12. Various mutants derived from 'Khao Dawk Mali 105' using gamma radiation

    Science.gov (United States)

    Mutations induced by radiation and chemicals have been widely used for genetic studies and cultivar improvement. Khao Dawk Mali 105 (KDM105), an aromatic cultivar from Thailand, is globally known for its premium quality. Seeds of KDM105 were obtained from the International Rice Research Institute (I...

  13. Evaluation of the onset and length of growing season to define planting date—`a case study for Mali (West Africa)'

    Science.gov (United States)

    Akinseye, F. M.; Agele, S. O.; Traore, P. C. S.; Adam, M.; Whitbread, A. M.

    2016-05-01

    The agroecological zones (AEZ) of Mali fall within the semi-arid climate, the ability to determine efficiently or predict accurately the onset of growing season (OGS), and length of growing season (LGS) cannot be over-emphasized due to highly variable rainfall pattern and the dependence of smallholder farmers practising on rainfed farming agriculture. In this study, we determined the most suitable method for predicting the onset date of rainfall across AEZ that fitted with the planting windows of major cereal crops (maize, millet, and sorghum). Using long-term daily rainfall records from 22 meteorological stations spread across AEZ of Mali, four (4) known methods were applied to determine the onset dates of the rain. The mean onset dates were statistically compared with the farmer's planting window for the selected weather stations to determine the suitable dates of OGS and LGS. The hypothesis considered a time lag minimum of 7 days between the mean onset date and traditional farmer sowing dates for the crops. Then, the preferred method was used to estimate OGS based on early, normal and late dates respectively across the stations. Also, the estimated LGS according to each zone was evaluated using probability distribution chart with duration to maturity for varieties of the same crops. The results showed that Def_4 was found appropriate for Sahelian and Sudano-Sahelian zones; Def_3 satisfied the criteria and exhibited superior capacity into farmer's average planting date over Sudanian and Guinea Savannah zones. These results have an important application in cropping systems in order to prevent crop failure and ensure a better choice of crop variety according to LGS under climate variability and change being experienced across Mali.

  14. Etiology and Factors Associated with Pneumonia in Children under 5 Years of Age in Mali: A Prospective Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Thomas Bénet

    Full Text Available There are very limited data on children with pneumonia in Mali. The objective was to assess the etiology and factors associated with community-acquired pneumonia in hospitalized children <5 years of age in Mali.A prospective hospital-based case-control study was implemented in the Pediatric department of Gabriel Touré University Hospital at Bamako, Mali, between July 2011-December 2012. Cases were children with radiologically-confirmed pneumonia; Controls were hospitalized children without respiratory features, matched for age and period. Respiratory specimens, were collected to identify 19 viruses and 5 bacteria. Whole blood was collected from cases only. Factors associated with pneumonia were assessed by multivariate logistic regression.Overall, 118 cases and 98 controls were analyzed; 44.1% were female, median age was 11 months. Among pneumonia cases, 30.5% were hypoxemic at admission, mortality was 4.2%. Pneumonia cases differed from the controls regarding clinical signs and symptoms but not in terms of past medical history. Multivariate analysis of nasal swab findings disclosed that S. pneumoniae (adjusted odds ratio [aOR] = 3.4, 95% confidence interval [95% CI]: 1.6-7.0, human metapneumovirus (aOR = 17.2, 95% CI: 2.0-151.4, respiratory syncytial virus [RSV] (aOR = 7.4, 95% CI: 2.3-23.3, and influenza A virus (aOR = 10.7, 95% CI: 1.0-112.2 were associated with pneumonia, independently of patient age, gender, period, and other pathogens. Distribution of S. pneumoniae and RSV differed by season with higher rates of S. pneumoniae in January-June and of RSV in July-September. Pneumococcal serotypes 1 and 5 were more frequent in pneumonia cases than in the controls (P = 0.009, and P = 0.04, respectively.In this non-PCV population from Mali, pneumonia in children was mainly attributed to S. pneumoniae, RSV, human metapneumovirus, and influenza A virus. Increased pneumococcal conjugate vaccine coverage in children could significantly reduce the

  15. EDUCATION, COMMUNITY AND RACIAL-ETHNIC RELATIONS: EXPERIENCES IN THE UNITED STATES AND MALI

    Directory of Open Access Journals (Sweden)

    Joyce E. King

    2012-11-01

    Full Text Available Black students, as a group, are underserved by neoliberal policies and poorly resourced urban schools and Black Americans are over-represented in privatized prisons. This article challenges cultural deficit thinking and theorizing about Black children’s language and culture, which have been so pervasive in the U.S.Research discussed in this article interrupts this discourse of Black inferiority and highlights the importance of students developing a critical Black consciousness,which can contribute to their academic and cultural excellence. Emancipatory pedagogy for human freedom, which supports students’ positive sense of themselves and their racial-ethnic group, is also discussed. Emancipatory teachingfor critical Black consciousness and human freedom means recovering history, memory and identity, so students understand the state of Black America from a critical,historical perspective. Education for this kind of consciousness requires connecting students to their family, community history and to their ancestors. Five principles ofemancipatory pedagogy are presented that can guide teacher preparation, curriculum, text development, and standards-based instruction and support positive racial-ethnic relationships. These are: conscientization, critique of ideology/critique of racism as ideology, cultural agency/resistance to oppression, dialecticalepistemology and teaching through cultural arts. The example of the Songhoy Club, a pedagogical laboratory for heritage teaching for students and doctoral students and engaging parents, demonstrates how teaching Songhoy language and culture connects students with their African heritage, “from the Nile to the Niger to the Neighborhood.” Teaching this heritage is very important given that northern Mali is occupied by Islamic extremists who have destroyed historiccultural artifacts in Timbuktu.

  16. In situ measurements of suspended sediment transport in the wadi dourou (''pays Dogon'' - Mali)

    International Nuclear Information System (INIS)

    A nuclear gauge has been installed in the riverbed of little wadi in the ''pays Dogon'' in order to measure the sediment transport during the floods. The region, formed by outcrops of precambrien sandstones and little valleys filled by sandy alluvial deposit, undergoes intense erosion due to violent storms during the rainy season. The phenomenon is furthermore aggravated by deforestation processes which reduce natural infiltration of water and increase surface run-off. Like all water courses on the plateau, the ''Dourou'' wadi is ephemeral and runs only during the rainy season with very short and violent floods after rain events. The principle of the sediment transport measurements is based on the absorption of gamma rays between a nuclear source (Am-241) and a detector, both installed in the wadi-bed. As the gauge response depends on the geometry of the system (mainly distance source - detector) and on the mineralogic nature of the suspended sediments, a proper calibration curve should be determined before application in the field. Measurements made during the rainy season 1990 and 1991 has shown a sediment transport of some tens to several hundred tons depending on the force of the storms. The total amount during one rainy season has been estimated to about 5,000 tons which would given an average erosion rate of about 10tonnes/km2/year on the basin. The main advantages of the method consist, especially in remote regions of difficult access, in the possibilities of automatic and continuous measurements. The equipment installed in Mali has provided fundamental information on erosion processes on the ''plateau Dogon''. In this particular case, however, the geometry of the system would have to be modified in order to enable measurements of the sediment transport at the very beginning of the floods. (author). 10 refs, 7 figs, 1 tab

  17. A development-based compartmentalization of the Drosophila central brain

    OpenAIRE

    Pereanu, Wayne; Kumar, Abilasha; Jennett, Arnim; Reichert, Heinrich; Hartenstein, Volker

    2010-01-01

    The neuropile of the Drosophila brain is subdivided into anatomically discrete compartments. Compartments are rich in terminal neurite branching and synapses; they are the neuropile domains in which signal processing takes place. Compartment boundaries are defined by more or less dense layers of glial cells, as well as long neurite fascicles. These fascicles are formed during the larval period when the approximately 100 neuronal lineages that constitute the Drosophila central brain differenti...

  18. Weighting links based on edge centrality for community detection

    Science.gov (United States)

    Sun, Peng Gang

    2014-01-01

    Link weights have the equally important position as links in complex networks, and they are closely associated with each other for the emergence of communities. How to assign link weights to make a clear distinction between internal links of communities and external links connecting communities is of vital importance for community detection. Edge centralities provide a powerful approach for distinguishing internal links from external ones. Here, we first use edge centralities such as betweenness, information centrality and edge clustering coefficient to weight links of networks respectively to transform unweighted networks into weighted ones, and then a weighted function that both considers links and link weights is adopted on the weighted networks for community detection. We evaluate the performance of our approach on random networks as well as real-world networks. Better results are achieved on weighted networks with stronger weights of internal links of communities, and the results on unweighted networks outperform that of weighted networks with weaker weights of internal links of communities. The availability of our findings is also well-supported by the study of Granovetter that the weak links maintain the global integrity of the network while the strong links maintain the communities. Especially in the Karate club network, all the nodes are correctly classified when we weight links by edge betweenness. The results also give us a more comprehensive understanding on the correlation between links and link weights for community detection.

  19. The linear chromosome of the plant-pathogenic mycoplasma 'Candidatus Phytoplasma mali'

    Directory of Open Access Journals (Sweden)

    Migdoll Alexander M

    2008-06-01

    Full Text Available Abstract Background Phytoplasmas are insect-transmitted, uncultivable bacterial plant pathogens that cause diseases in hundreds of economically important plants. They represent a monophyletic group within the class Mollicutes (trivial name mycoplasmas and are characterized by a small genome with a low GC content, and the lack of a firm cell wall. All mycoplasmas, including strains of 'Candidatus (Ca. Phytoplasma asteris' and 'Ca. P. australiense', examined so far have circular chromosomes, as is the case for almost all walled bacteria. Results Our work has shown that 'Ca. Phytoplasma mali', the causative agent of apple proliferation disease, has a linear chromosome. Linear chromosomes were also identified in the closely related provisional species 'Ca. P. pyri' and 'Ca. P. prunorum'. The chromosome of 'Ca. P. mali' strain AT is 601,943 bp in size and has a GC content of 21.4%. The chromosome is further characterized by large terminal inverted repeats and covalently closed hairpin ends. Analysis of the protein-coding genes revealed that glycolysis, the major energy-yielding pathway supposed for 'Ca. P. asteris', is incomplete in 'Ca. P. mali'. Due to the apparent lack of other metabolic pathways present in mycoplasmas, it is proposed that maltose and malate are utilized as carbon and energy sources. However, complete ATP-yielding pathways were not identified. 'Ca. P. mali' also differs from 'Ca. P. asteris' by a smaller genome, a lower GC content, a lower number of paralogous genes, fewer insertions of potential mobile DNA elements, and a strongly reduced number of ABC transporters for amino acids. In contrast, 'Ca. P. mali' has an extended set of genes for homologous recombination, excision repair and SOS response than 'Ca. P. asteris'. Conclusion The small linear chromosome with large terminal inverted repeats and covalently closed hairpin ends, the extremely low GC content and the limited metabolic capabilities reflect unique features of 'Ca

  20. La francophonie menacée? : la percée de l'anglais dans un pays francophone : le cas du Mali

    OpenAIRE

    2005-01-01

    THE FRENCH LANGUAGE AT STAKE? The influence of English in a francophone country: the case of Mali. During a period of three years’ stay in Mali, an arid country in the western part of the great African Sahel area, an interesting phenomenon attracted my attention: the extraordinary interest in the English language. Mali is a multi-linguistic country with more than twenty ethnic groups and a corresponding number of local languages. Among these, Bambara is the national lingua franca, while...

  1. 'Love of the heart': romantic love among young mothers in Mali.

    Science.gov (United States)

    Sølbeck, Ditte Enemark

    2010-05-01

    This paper calls attention to an ideal of romantic love among young unmarried mothers in Mali. It demonstrates that romantic love constitutes a motivating force for the agency of young Malian mothers who invest themselves in hopes of romantic outcomes from their relationships. Like the majority of people in Mali, the young mothers in this study dedicated a considerable time each weekday to watching a Venezuelan soap opera, which could be regarded as offering a modern version of Romeo and Juliet. Yet, romance is not the only thing that matters in young mothers' ideals of love. Materiality plays an important role as well. Thus, young mothers have multiple motives for engaging in relationships with men: they seek both romance and material stability, which is why an either love or exchange perspective is insufficient when examining the topic of romantic love in a Malian context.

  2. When is a central bank governor replaced? Evidence based on a new data set

    NARCIS (Netherlands)

    Dreher, Axel; Sturm, Jan-Egbert; de Haan, Jakob

    2010-01-01

    Using new data on the term in office of central bank governors for a large set of countries for 1970-2005, we estimate a model for the probability that a central bank governor is replaced before the end of his legal term in office. We formulate hypotheses based on the literature on the determinants

  3. Appropriate training and retention of community doctors in rural areas: a case study from Mali

    OpenAIRE

    Coulibaly Seydou; Kone Yacouba; Dugas Sylvie; Van Dormael Monique; Sy Mansour; Marchal Bruno; Desplats Dominique

    2008-01-01

    Abstract Background While attraction of doctors to rural settings is increasing in Mali, there is concern for their retention. An orientation course for young practicing rural doctors was set up in 2003 by a professional association and a NGO. The underlying assumption was that rurally relevant training would strengthen doctors' competences and self-confidence, improve job satisfaction, and consequently contribute to retention. Methods Programme evaluation distinguished trainees' opinions, co...

  4. Impact of Climate Change on Groundwater Resources in the Klela Basin, Southern Mali

    OpenAIRE

    Adama Toure; Bernd Diekkrüger; Adama Mariko

    2016-01-01

    Investigations of groundwater resources in order to understand aquifer system behavior are vital to the inhabitants of the Klela Basin, Mali, because groundwater is the only permanent water resource and is used for drinking water and irrigation. Due to climate change, this vital resource is being threatened. Therefore, MODFLOW was applied in this study to simulate groundwater dynamics. The aim of this study was to evaluate the impact of climate change on groundwater resources in the Klela bas...

  5. [Contraception and protection against STDs. CERPOD measures use of the Protector condom in Mali].

    Science.gov (United States)

    Konate, M K

    1993-08-01

    In April 1993, a technical assistance contract to measure general condom use, particularly use of the brand name Protector, which has been marketed in Mali since March 1992, was made between the Center of Studies and Research on Population for Development (CERPOD) and the Popular Pharmacy of Mali. In June-July 1991, the SOMARC project and the Malian Institute for Applied Research in Development conducted a baseline survey to determine the condom use rate in Mali before Protector was introduced on the Malian market, so the social marketing project for contraception could be evaluated. It examined knowledge, use, and achievable target level and determined the characteristics of users of the Protector condom. It revealed that more than 90% of both men and women believed birth spacing was a good idea. Men approved of birth spacing for cost-saving reasons, while women approved birth spacing because it allowed mothers time to recuperate between births. Another earlier study in 1987 in Bamako found that 78% of the women already favored birth spacing. 90% of the men in the main cities in Mali knew about condoms. 63% of these men had used them in the past, mainly to prevent sexually transmitted diseases. 30% used them consistently. One hoped that this number was going to grow, since 80% of the men said that they would use condoms in the future. The evaluation of the 1991 social marketing campaign will end in August 1993 and will measure whether it was successful or not. In November 1992, CERPOD followed the framework of a recent baseline survey for an IEC (information, education, and communication) family planning program, operated jointly by the Malian Association for the Protection and Promotion of the Family and Population Communication Services, to measure the effect of the brand name Protector. CERPOD's survey results will be compared with those of the 1993 survey.

  6. Implementing preventive chemotherapy through an integrated National Neglected Tropical Disease Control Program in Mali.

    Directory of Open Access Journals (Sweden)

    Massitan Dembélé

    Full Text Available BACKGROUND: Mali is endemic for all five targeted major neglected tropical diseases (NTDs. As one of the five 'fast-track' countries supported with the United States Agency for International Development (USAID funds, Mali started to integrate the activities of existing disease-specific national control programs on these diseases in 2007. The ultimate objectives are to eliminate lymphatic filariasis, onchocerciasis and trachoma as public health problems and to reduce morbidity caused by schistosomiasis and soil-transmitted helminthiasis through regular treatment to eligible populations, and the specific objectives were to achieve 80% program coverage and 100% geographical coverage yearly. The paper reports on the implementation of the integrated mass drug administration and the lessons learned. METHODOLOGY/PRINCIPAL FINDINGS: The integrated control program was led by the Ministry of Health and coordinated by the national NTD Control Program. The drug packages were designed according to the disease endemicity in each district and delivered through various platforms to eligible populations involving the primary health care system. Treatment data were recorded and reported by the community drug distributors. After a pilot implementation of integrated drug delivery in three regions in 2007, the treatment for all five targeted NTDs was steadily scaled up to 100% geographical coverage by 2009, and program coverage has since been maintained at a high level: over 85% for lymphatic filariasis, over 90% for onchocerciasis and soil-transmitted helminthiasis, around 90% in school-age children for schistosomiasis, and 76-97% for trachoma. Around 10 million people have received one or more drug packages each year since 2009. No severe cases of adverse effects were reported. CONCLUSIONS/SIGNIFICANCE: Mali has scaled up the drug treatment to national coverage through integrated drug delivery involving the primary health care system. The successes and lessons

  7. First report of Echinococcus granulosus (genotype G6) in a dog in Bamako, Mali.

    Science.gov (United States)

    Mauti, S; Traoré, A; Crump, L; Zinsstag, J; Grimm, F

    2016-02-15

    Cystic echinococcosis is one of the most widespread and important helminthic zoonoses, caused by the larval stage of Echinococcus granulosus sensu lato. However, to date there is little information about the disease in West Africa. Faecal and fur samples from 193 dogs, the main final hosts, were collected in 2010 and 2011 in Bamako, Mali. Taeniid eggs were found microscopically in 28/118 (24%) and 80/223 (36%) faecal and fur samples, respectively. One faecal and one fur sample from the same dog were positive for E. granulosus s. l. DNA. In the remaining 27 faecal (96%) and 77 fur samples (96%) only Taenia DNA was detected. Three microscopically positive fur samples were negative by PCR. Sequence analysis of part of the NADH dehydrogenase subunit 1 gene identified the parasite as E. granulosus (genotype G6; Echinococcus canadensis). This is the first study to focus on the final host of E. granulosus s. l. in Mali and the first report of E. canadensis in Mali.

  8. A development-based compartmentalization of the Drosophila central brain

    Science.gov (United States)

    Pereanu, Wayne; Kumar, Abilasha; Jennett, Arnim; Reichert, Heinrich; Hartenstein, Volker

    2010-01-01

    The neuropile of the Drosophila brain is subdivided into anatomically discrete compartments. Compartments are rich in terminal neurite branching and synapses; they are the neuropile domains in which signal processing takes place. Compartment boundaries are defined by more or less dense layers of glial cells, as well as long neurite fascicles. These fascicles are formed during the larval period when the approximately 100 neuronal lineages that constitute the Drosophila central brain differentiate. Each lineage forms an axon tract with a characteristic trajectory in the neuropile; groups of spatially related tracts congregate into the brain fascicles that can be followed from the larva throughout metamorphosis into the adult stage. In this paper we provide a map of the adult brain compartments and the relevant fascicles defining compartmental boundaries. We have identified the neuronal lineages contributing to each fascicle, which allowed us to directly compare compartments of the larval and adult brain. Most adult compartments can be recognized already in the early larval brain where they form a “protomap” of the later adult compartments. Our analysis highlights the morphogenetic changes shaping the Drosophila brain; the data will be important for studies that link early acting genetic mechanisms to the adult neuronal structures and circuits controlled by these mechanisms. PMID:20533357

  9. Development-based compartmentalization of the Drosophila central brain.

    Science.gov (United States)

    Pereanu, Wayne; Kumar, Abilasha; Jennett, Arnim; Reichert, Heinrich; Hartenstein, Volker

    2010-08-01

    The neuropile of the Drosophila brain is subdivided into anatomically discrete compartments. Compartments are rich in terminal neurite branching and synapses; they are the neuropile domains in which signal processing takes place. Compartment boundaries are defined by more or less dense layers of glial cells as well as long neurite fascicles. These fascicles are formed during the larval period, when the approximately 100 neuronal lineages that constitute the Drosophila central brain differentiate. Each lineage forms an axon tract with a characteristic trajectory in the neuropile; groups of spatially related tracts congregate into the brain fascicles that can be followed from the larva throughout metamorphosis into the adult stage. Here we provide a map of the adult brain compartments and the relevant fascicles defining compartmental boundaries. We have identified the neuronal lineages contributing to each fascicle, which allowed us to compare compartments of the larval and adult brain directly. Most adult compartments can be recognized already in the early larval brain, where they form a "protomap" of the later adult compartments. Our analysis highlights the morphogenetic changes shaping the Drosophila brain; the data will be important for studies that link early-acting genetic mechanisms to the adult neuronal structures and circuits controlled by these mechanisms. PMID:20533357

  10. Ground-based Fourier transform infrared spectroscopy in central Mexico

    Science.gov (United States)

    Plaza, Eddy; Stremme, Wolfgang; Bezanilla, Alejandro; Baylon, Jorge; Grutter, Michel; Blumenstock, Thomas; Hase, Frank

    2014-05-01

    Altzomoni is a high altitude station in central Mexico (19.12 N, 98.65 W, 4000 m a.s.l.) for continuous measurements of various atmospheric parameters. It is located within the Izta-Popo National Park and is operated remotely from the UNAM campus. Since May 2012, high resolution solar absorption spectra have been recorded from this site using a FTIR from Bruker (HR120/5) equipped with MCT, InSb and InGaAs detectors and various optical filters. In this contribution we present a detailed description of the measurement site and the instrumental set-up including a record of the instrumental line-shapes (modulation efficiency and phase error) obtained from cell measurements and analyzed with the LINEFIT code. A preliminary analysis of almost two years of spectra recorded at the Altzomoni site resulting in profile retrievals of four NDACC gases O3, CO, HF and HCl is presented. The retrieval code PROFFIT is used and the Averaging Kernels and an error analysis are used to describe the quality of the measurements. The annual cycles in the time series of O3 and CO are presented and discussed, as well as some examples of anomalies due to volcanic gas emissions of HF and HCl are shown. The presented work is part of an effort to certify this station as part of the NDACC international network.

  11. Biofilm-based central line-associated bloodstream infections.

    Science.gov (United States)

    Yousif, Ammar; Jamal, Mohamed A; Raad, Issam

    2015-01-01

    Different types of central venous catheters (CVCs) have been used in clinical practice to improve the quality of life of chronically and critically ill patients. Unfortunately, indwelling devices are usually associated with microbial biofilms and eventually lead to catheter-related bloodstream infections (CLABSIs).An estimated 250,000-400,000 CLABSIs occur every year in the United States, at a rate of 1.5 per 1,000 CVC days and a mortality rate of 12-25 %. The annual cost of caring for patients with CLABSIs ranges from 296 million to 2.3 billion dollars.Biofilm formation occurs on biotic and abiotic surfaces in the clinical setting. Extensive studies have been conducted to understand biofilm formation, including different biofilm developmental stages, biofilm matrix compositions, quorum-sensing regulated biofilm formation, biofilm dispersal (and its clinical implications), and multi-species biofilms that are relevant to polymicrobial infections.When microbes form a matured biofilm within human hosts through medical devices such as CVCs, the infection becomes resistant to antibiotic treatment and can develop into a chronic condition. For that reason, many techniques have been used to prevent the formation of biofilm by targeting different stages of biofilm maturation. Other methods have been used to diagnose and treat established cases of CLABSI.Catheter removal is the conventional management of catheter associated bacteremia; however, the procedure itself carries a relatively high risk of mechanical complications. Salvaging the catheter can help to minimize these complications.In this article, we provide an overview of microbial biofilm formation; describe the involvement of various genetic determinants, adhesion proteins, organelles, mechanism(s) of biofilm formation, polymicrobial infections, and biofilm-associated infections on indwelling intravascular catheters; and describe the diagnosis, management, and prevention of catheter-related bloodstream infections

  12. Prioritization of Watersheds across Mali Using Remote Sensing Data and GIS Techniques for Agricultural Development Planning

    Directory of Open Access Journals (Sweden)

    Murali Krishna Gumma

    2016-06-01

    Full Text Available Implementing agricultural water management programs over appropriate spatial extents can have positive effects on water access and erosion management. Lack of access to water for domestic and agricultural uses represents a major constraint on agricultural productivity and perpetuates poverty and hunger in sub-Saharan Africa (SSA. This lack of access is the result of erratic precipitation, poor water management, limited knowledge of hydrological systems, and inadequate investment in water infrastructure. Water management programs should be made by multi-disciplinary teams that consider the interrelationship between hydraulic and anthropogenic factors. This paper proposes a method to prioritize watersheds for water management and agricultural development across Mali (Western Africa using remote sensing data and GIS tools. The method involves deriving a set of relevant thematic layers from satellite imagery. Satellite images from Landsat ETM+ were used to generate thematic layers such as land use/land cover. Slope and drainage density maps were derived from Shuttle RADAR Topography Mission (SRTM Digital Elevation Model (DEM at 90 m spatial resolution. Population grids were available from the Global rural-urban mapping project (GRUMP database for the year 2000 and mean rainfall maps were extracted from Tropical rainfall measuring mission (TRMM grids for each year between 1988 and 2014. Each thematic layer was divided into classes that were assigned a rank for agriculture and livelihoods development provided by experts in the relevant field (e.g., Soil scientist ranking the soil classes and published literature on those themes. Zones of priority were delineated based on the combination of high scoring ranks from each thematic layer. Five categories of priority zones ranging from “very high” to “very low” were determined based on total score percentages. Field verification was then undertaken in selected categories to check the priority

  13. Transoral robotic surgery of the central skull base: preclinical investigations.

    Science.gov (United States)

    Fernandez-Nogueras, F J J; Katati, M J; Arraez Sanchez, M A; Molina Martinez, M; Sanchez Carrion, M

    2014-06-01

    In this study we explored possible applications of the da Vinci system in approaching the skull base at optic chiasm level on two cryopreserved cadavers, using an entirely transoral robotic technique (TORS). We used a standard 12 mm endoscopy and 8 mm terminals. Bone drilling was performed manually. The da Vinci system is equipped with very good illumination and 3D viewing, thus providing excellent vision and great maneuverability even in the less accessible areas of the skull. Our experience demonstrates that an entirely transoral skull base robotic approach to this complex anatomical region has many advantages as compared to traditional techniques. PMID:24077869

  14. Centralized computer-based controls of the Nova Laser Facility

    International Nuclear Information System (INIS)

    This article introduces the overall architecture of the computer-based Nova Laser Control System and describes its basic components. Use of standard hardware and software components ensures that the system, while specialized and distributed throughout the facility, is adaptable. 9 references, 6 figures

  15. [A cutting obstacle to the harmonious development of the country. The migratory phenomenon in Mali].

    Science.gov (United States)

    Diarra, S

    1991-04-01

    Mali has long been affected by migration because of its location between North Africa and sub-Saharan Africa. Around 80% of the population depends on agriculture or herding for its livelihood. During the rainy season, from June-October, most of the population is busy in agricultural work, but during the dry season from November to May seasonal migration in search of wage employment is common. Seasonal migration is also part of the long tradition of commerce with neighboring countries. Economic difficulties of the last several years have encourage migration to urban centers and foreign countries. The drought that has afflicted Mali for over a decade is a further impetus to migration. 2 types of migration can be distinguished in Mali, shortterm movements of nomads and seasonal migration lasting less than 6 months, and definitive movements lasting longer including rural-urban and international migration. 4 further categories of migration include rural-rural movements especially in the south and in areas of industrial development, rural-urban migrations which are 1 of the most important factors in rapid urban growth especially around Bamako,, urban-urban migration essentially reflecting step migration from rural areas to secondary urban centers and finally to large cities, and urban-rural migration which occurs much less frequently. Over 80% of temporary movements take place within Mali. About 80% of those residing temporarily outside Mali are men. Temporary migrants inside Mali are oriented from the north to the region of Sikasso and the District of Bamako in the south and primarily are young men aged 15-29. There has been a progressive decline in the proportion of nomads in the general population from 7% in 1976 to 4% in 1987. There has been an increase in definitive migration from areas less favored ecologically to more desirable areas. A 1985 demographic survey found that 21% of the population aged 15 or over were migrants. 51.4% of migrants were male. 86% cited

  16. Stability of Spatial Structure of Urban Agglomeration in China Based on Central Place Theory

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    This paper brings forward the concept of stability of the spatial structure of urban agglomeration (UA) based on Central Place Theory by introducing centrality index and fractal theory. Before assessment, K=4 is selected as parameter to calculate centrality index and fractal dimension (K represents the quantitive relationship between city and the counties in Central Place Theory), and then found the number of nodes, the type of spatial structure, the spatial allocation of nodes with different hierarchy affecting the stability of spatial structure. According to spatial contact direction and the level of stability, UAs in China are classified into five types. Finally, it is posed as a further question that how to use hierarchical relation K=6 and K=7 in central place system to coordinate with the assessment of stability of spatial structure is brought forward.

  17. Using modeling, satellite images and existing global datasets for rapid preliminary assessments of renewable energy resources: The case of Mali

    International Nuclear Information System (INIS)

    This paper presents a novel approach to the preliminary, low-cost, national-scale mapping of wind energy, solar energy and certain categories of bio-energy resources in developing countries, using Mali as an example. The methods applied make extensive use of satellite remote sensing and meteorological mesoscale modeling. The paper presents first results from applying the methodology in Mali and discusses the appropriateness of the results obtained. It is shown that northern Mali has considerable wind energy potential, while average wind speeds in the southern part are too low to make wind power a competitive option. Solar energy resources are shown to be abundant in all of Mali, though the highest values are found in the south. The temporal variation is relatively limited. Bio-energy resources are also concentrated in the south, but there are small pockets of high vegetation productivity in the irrigated areas of the Niger inland delta that might be interesting from a renewable energy resource perspective. Finally, the paper discusses the role that renewable energy resources might play in the energy systems of Mali, given the spatio-temporal distribution of renewable energy resources. It is argued that at the current price of about 70 US$/barrel for fossil fuels, renewable energy resources are becoming economically as well as environmentally attractive options. (author)

  18. Food Groups Associated with a Composite Measure of Probability of Adequate Intake of 11 Micronutrients in the Diets of Women in Urban Mali

    NARCIS (Netherlands)

    Kennedy, G.L.; Fanou-Fogny, N.M.L.; Seghieri, C.; Arimond, M.; Koreissi, Y.; Dossa, R.A.M.; Kok, F.J.; Brouwer, I.D.

    2010-01-01

    The prevalence of micronutrient deficiency is high among women of reproductive age living in urban Mali. Despite this, there are little data on the dietary intake of micronutrients among women of reproductive age in Mali. This research tested the relationship between the quantity of intake of 21 pos

  19. Eigenvector Centrality Based on Shared Research Topics in a Scientific Community

    OpenAIRE

    Volpentesta, Antonio P.; Felicetti, Alberto M.

    2010-01-01

    In this paper we propose a weighted multi-hypergraph as logical structure to model relationships between researchers and interest groups that join them on the base of shared research topics in a given scientific community. The well known concept of eingenvector centrality for graphs is extended to weighted multi-hypergraphs and we present a model instantiation for centrality analysis in the Pro-VE scientific community.

  20. Incremental Algorithms for Network Management and Analysis based on Closeness Centrality

    OpenAIRE

    Sariyuce, Ahmet Erdem; Kaya, Kamer; Saule, Erik; Catalyurek, Umit V.

    2013-01-01

    Analyzing networks requires complex algorithms to extract meaningful information. Centrality metrics have shown to be correlated with the importance and loads of the nodes in network traffic. Here, we are interested in the problem of centrality-based network management. The problem has many applications such as verifying the robustness of the networks and controlling or improving the entity dissemination. It can be defined as finding a small set of topological network modifications which yiel...

  1. User fee exemptions and equity in access to caesarean sections: an analysis of patient survey data in Mali

    Directory of Open Access Journals (Sweden)

    El-Khoury Marianne

    2012-08-01

    Full Text Available Abstract Introduction Little rigorous evidence exists on how health service utilization varies across socioeconomic groups after a user fee exemption policy has been implemented, and the evidence that does exist is mixed. In this paper, we estimate the distribution of caesarean section deliveries across socioeconomic groups following Mali’s implementation of a fee exemption policy for caesareans in 2005. Methods We conducted a patient survey in 2010 to collect socioeconomic data from 2,477 women who had caesareans in a representative sample of 25 facilities across all regions of Mali. We used these data along with data from the most recent Demographic and Health Survey to construct a wealth index and classify women into population-based wealth groupings. We compared the wealth distribution of women delivering via caesarean section to that of a nationally representative sample of women giving birth. Results We found that wealthier women make up a disproportionate share of those having free caesareans, five years after implementation of the fee exemption policy. Women in the richest two quintiles accounted for 58 percent of all caesareans, while women in the poorest two quintiles accounted for 27 percent of all caesareans. Fewer women in the poorest two-fifths of the population are receiving caesareans than what we would expect given their share in the population of women giving birth. Conclusions While fee exemptions remove important financial barriers to accessing priority maternal health services, they are insufficient to ensure equal access among wealth groups.

  2. Empowering communities in combating river blindness and the role of NGOs: case studies from Cameroon, Mali, Nigeria, and Uganda

    Directory of Open Access Journals (Sweden)

    Meredith Stefanie E O

    2012-05-01

    Full Text Available Abstract The control of onchocerciasis is not only a major success story in global health, but also one of the best examples of the power of public-private partnership at the international level as well as at the national level. The onchocerciasis story is also a leading example of the contribution of a group of called Non-Governmental Development Organizations (NGDO to operational research which resulted in important changes in treatment strategies and policies. The four case studies presented here illustrate some key contributions the NGDOs made to the development of “community directed treatment with ivermectin” –CDTI, in Africa, which became the approved methodology within the African Programme for Onchocerciasis Control (APOC. The partnership between the international, multilateral, government institutions and the NGDO Coordination Group was the backbone of the APOC programme’s structure and facilitated progress and scale-up of treatment programmes. Contributions included piloting community–based methodology in Mali and Nigeria; research, collaboration and coordination on treatment strategies and policies, coalition building, capacity building of national health workforce and advocacy at the national and international level. While the Onchocerciasis Control Programme (OCP and APOC provided leadership, the NGDOs working with the national health authorities played a major role in advocacy evolving the community methodology which led to achieving and maintaining- treatments with ivermectin for at least 20 years and strengthening community health systems.

  3. Ostrich-Like Strategies in Sahelian Sands? Land and Water Grabbing in the Office du Niger, Mali

    Directory of Open Access Journals (Sweden)

    Thomas Hertzog

    2012-06-01

    Full Text Available In recent years, large-scale agricultural investment projects have increased in sub-Saharan Africa as a result of the growing appetites of local and international investors for land resources. Research has so far mainly focused on land issues, but the water implications of these land deals are starting to surface. Taking the Office du Niger (ON, in Mali, as a case study, we show that while around 100,000 ha is currently being cultivated, mostly by smallholders, a total of 600,000 ha of land has been allocated in the past ten years to investors in large-scale farming. This process has largely bypassed the official procedure established by the ON at regional level. The allocation of new lands has shifted to the national level, with an attempt to recentralize the management of land deals and associated benefits at the highest level, despite contrary efforts by foreign donors to strengthen the ON. This article describes the complex allocation process based on 'behind-closed-doors' negotiations. It then analyses the implications of the land deals on water issues by focusing on the strategies of actors to limit the risk of future water shortages, the current and expected difficulties in water management and allocation, and the emerging spatial and social redistribution of benefits and risk that signals a process of water grabbing.

  4. Caribbean and Central American Women's Feminist Inquiry through Theater-Based Action Research

    Science.gov (United States)

    Sánchez Ares, Rocío

    2015-01-01

    Feminist action research interrogates gendered dynamics in the development of a collective consciousness. A group of immigrant Latina women (Latinas) from the Caribbean and Central America employed community-based theater as an instrument to mobilize diverse audiences against discriminatory practices and policies. Based on their theater work, I…

  5. Spatial drought reconstructions for central High Asia based on tree rings

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Keyan [Lanzhou University, Key Laboratory of Western Chinese Environmental Systems (MOE), Center for Arid Environment and Paleoclimate Research (CAEP), Lanzhou (China); Columbia University, Tree-Ring Lab, Lamont-Doherty Earth Observatory, Palisades, NY (United States); Davi, Nicole; Cook, Edward; Li, Jinbao; D' Arrigo, Rosanne [Columbia University, Tree-Ring Lab, Lamont-Doherty Earth Observatory, Palisades, NY (United States); Gou, Xiaohua; Chen, Fahu [Lanzhou University, Key Laboratory of Western Chinese Environmental Systems (MOE), Center for Arid Environment and Paleoclimate Research (CAEP), Lanzhou (China)

    2010-11-15

    Spatial reconstructions of drought for central High Asia based on a tree-ring network are presented. Drought patterns for central High Asia are classified into western and eastern modes of variability. Tree-ring based reconstructions of the Palmer drought severity index (PDSI) are presented for both the western central High Asia drought mode (1587-2005), and for the eastern central High Asia mode (1660-2005). Both reconstructions, generated using a principal component regression method, show an increased variability in recent decades. The wettest epoch for both reconstructions occurred from the 1940s to the 1950s. The most extreme reconstructed drought for western central High Asia was from the 1640s to the 1650s, coinciding with the collapse of the Chinese Ming Dynasty. The eastern central High Asia reconstruction has shown a distinct tendency towards drier conditions since the 1980s. Our spatial reconstructions agree well with previous reconstructions that fall within each mode, while there is no significant correlation between the two spatial reconstructions. (orig.)

  6. : The cuisine of Timbuktu (Mali), between sub-Saharan Africa and Maghreb

    OpenAIRE

    Chastanet, Monique

    2008-01-01

    Publication datée de 2008 mais parue effectivement au printemps 2009. Référence à corriger dans la bibliographie : Monique Chastanet, 2010, " Couscous 'à la sahélienne' (Sénégal, Mali, Mauritanie) " in FRANCONIE H., CHASTANET M. et SIGAUT F. (éd.), Couscous, boulgour et polenta. Transformer et consommer les céréales dans le monde, Paris, Karthala : 149-187. Erreur à corriger : page 49 de mon article, en évoquant la recette de la boisson au miel de Niaber Haïdara (2005 : 96), j'ai mentionné pa...

  7. Biblijska analogija u djelu Mali princ Antoinea de Saint Exupéryja

    OpenAIRE

    Slavić, Dean; Jambrišak, Ana

    2011-01-01

    Rad interpretira biblijski intertekst u djelu Mali princ francuskoga autora Antoinea de Saint Exupéryja. Naglašavaju se obilježja svete pripovijesti te ključni likovi koji su prefiguracije biblijskih osoba. Istražene su srodnosti manjih pripovijesti i rečenica iz djela s mudrim izrekama te naglašeni pojedini simboli iz kršćanske predaje, kakav je spomen božićnih darova. Djelo se pokazuje tekstom koji biblijske simbole mijenja stavljajući ih u novo surječje, ali zadržava poštivanje i bliskost ...

  8. Epidemic cholera in Mali: high mortality and multiple routes of transmission in a famine area.

    OpenAIRE

    Tauxe, R. V.; Holmberg, S D; Dodin, A.; Wells, J. V.; Blake, P A

    1988-01-01

    During the 1984 cholera epidemic in Mali, 1793 cases and 406 deaths were reported, a death-to-case ratio of 23%. In four affected villages, the mean clinical attack rate was 1.5 and 29% of affected persons died. In 66% of cases the illness began more than 48 h after the village outbreak began, when supplies from outside the village were potentially available. Deaths occurred because patients failed to seek care or received only limited rehydration therapy when they did. Case-control studies i...

  9. Constructing a survey over time: Audio-visual feedback and theatre sketches in rural Mali

    Directory of Open Access Journals (Sweden)

    Véronique Hertrich

    2011-10-01

    Full Text Available Knowledge dissemination is an emerging issue in population studies, both in terms of ethics and data quality. The challenge is especially important in long term follow-up surveys and it requires methodological imagination when the population is illiterate. The paper presents the dissemination project developed in a demographic surveillance system implemented in rural Mali over the last 20 years. After basic experience of document transfer, the feedback strategy was developed through audiovisual shows and theatre sketches. The advantages and drawbacks of these media are discussed, in terms of scientific communication and the construction of dialogue with the target population.

  10. Notes from the church of the Virgin at the island of Mali grad

    Directory of Open Access Journals (Sweden)

    Cvetkovski Sašo

    2010-01-01

    Full Text Available In this text the unknown parts of the wall paintings from the Church of the Virgin at the island of Mali Grad (The Great Prespa Lake are analyzed: the figure of a monk praying to St. Paraskeve, on the southern wall of the nave, as well as the painting on the southern faüade with the depictions of St. George on horseback, the Virgin as Empress enthroned, and the bust of two saints, St. Paraskeve and St. Nicholas. The monk is identified with the hegoumenos Jona, mentioned in the donor’s inscription dating from 1369.

  11. After the Fall of Qaddafi: Political, Economic, and Security Consequences for Libya, Mali, Niger, and Algeria

    Directory of Open Access Journals (Sweden)

    Ricardo René Larémont

    2013-06-01

    Full Text Available On 20 October 2011, Muammar Qaddafi, the leader of Libya, was killed by members of a local militia in his hometown of Sirte. Qaddafi’s death and his regime’s end fractured a security structure that had brought some stability to Libya, Mali, Niger, and to a much lesser extent southern Algeria. Because of his regime’s demise, a new swathe of instability that comprises fractured, compromised, or failed states has emerged in the Sahelian region, giving ample opportunities to militant entrepreneurial groups that have organized and are inhibiting the re-creation of more stable states and societies.

  12. "Une école pour la joie d´apprendre" - La Pédagogie Convergente : Umsetzung eines pädagogischen Konzeptes in der Grundbildung Malis

    OpenAIRE

    Krämer, Aline

    2006-01-01

    „Une école pour la joie d´apprendre“ lautet das Motto, mit dem das GTZ-Entwicklungshilfeprojekt „Projet Education de Base en 5e Région (PEB)“ in der 5. Verwaltungsregion von Mali, Westafrika, seit 2005 im Auftrag der Consulting ECOEducation, für seine Inhalte wirbt. Während Deutschland um seine schulmüden Jugendlichen kämpft, gibt es andere Orte auf der Welt, wo der „Hunger nach Bildung“ groß ist und viel Engagement in großen Teilen der Bevölkerung hervorruft. „In die Schule gehen“ ist oftmal...

  13. CentiServer: A Comprehensive Resource, Web-Based Application and R Package for Centrality Analysis.

    Directory of Open Access Journals (Sweden)

    Mahdi Jalili

    Full Text Available Various disciplines are trying to solve one of the most noteworthy queries and broadly used concepts in biology, essentiality. Centrality is a primary index and a promising method for identifying essential nodes, particularly in biological networks. The newly created CentiServer is a comprehensive online resource that provides over 110 definitions of different centrality indices, their computational methods, and algorithms in the form of an encyclopedia. In addition, CentiServer allows users to calculate 55 centralities with the help of an interactive web-based application tool and provides a numerical result as a comma separated value (csv file format or a mapped graphical format as a graph modeling language (GML file. The standalone version of this application has been developed in the form of an R package. The web-based application (CentiServer and R package (centiserve are freely available at http://www.centiserver.org/.

  14. The spatial distribution of Anopheles gambiae sensu stricto and An. arabiensis (Diptera: Culicidae in Mali

    Directory of Open Access Journals (Sweden)

    N. Sogoba

    2007-05-01

    Full Text Available Variations in the biology and ecology and the high level of genetic polymorphism of malaria vectors in Africa highlight the value of mapping their spatial distribution to enhance successful implementation of integrated vector management. The objective of this study was to collate data on the relative frequencies of Anopheles gambiae s.s. and An. arabiensis mosquitoes in Mali, to assess their association with climate and environmental covariates, and to produce maps of their spatial distribution. Bayesian geostatistical logistic regression models were fitted to identify environmental determinants of the relative frequencies of An. gambiae s.s. and An. arabiensis species and to produce smooth maps of their geographical distribution. The frequency of An. arabiensis was positively associated with the normalized difference vegetation index, the soil water storage index, the maximum temperature and the distance to water bodies. It was negatively associated with the minimum temperature and rainfall. The predicted map suggests that, in West Africa, An. arabiensis is concentrated in the drier savannah areas, while An. gambiae s.s. prefers the southern savannah and land along the rivers, particularly the inner delta of Niger. Because the insecticide knockdown resistance (kdr gene is reported only in An. gambiae s.s. in Mali, the maps provide valuable information for vector control. They may also be useful for planning future implementation of malaria control by genetically manipulated mosquitoes.

  15. Lyapunov-Based Control Scheme for Single-Phase Grid-Connected PV Central Inverters

    NARCIS (Netherlands)

    Meza, C.; Biel, D.; Jeltsema, D.; Scherpen, J. M. A.

    2012-01-01

    A Lyapunov-based control scheme for single-phase single-stage grid-connected photovoltaic central inverters is presented. Besides rendering the closed-loop system globally stable, the designed controller is able to deal with the system uncertainty that depends on the solar irradiance. A laboratory p

  16. Nitrogen phosphoric fertilizer production technology on the base of Central Kyzylkum phosphorites and ammonium nitrate melt

    OpenAIRE

    Shavkat Namazov; Akhmed Reymov; Nazarkul Pirmanov; Rashid Kurbaniyazov

    2012-01-01

    The process of obtaining nitrogen phosphoric fertilizer by introduction Central Kyzylkum phosphates and ammonium nitrate melt is studied. On the base of these results production technology diagram for nitrogen phosphoric fertilizer is offered. The given technology was approved and developed at the functioning devices of OJSC “NAVOIAZOT” ammonium nitrate shop.

  17. Nitrogen phosphoric fertilizer production technology on the base of Central Kyzylkum phosphorites and ammonium nitrate melt

    Directory of Open Access Journals (Sweden)

    Shavkat Namazov

    2012-11-01

    Full Text Available The process of obtaining nitrogen phosphoric fertilizer by introduction Central Kyzylkum phosphates and ammonium nitrate melt is studied. On the base of these results production technology diagram for nitrogen phosphoric fertilizer is offered. The given technology was approved and developed at the functioning devices of OJSC “NAVOIAZOT” ammonium nitrate shop.

  18. Understanding Urban Spatial Structure of Shanghai Central City Based on Mobile Phone Data

    Institute of Scientific and Technical Information of China (English)

    Niu; Xinyi; Ding; Liang; Song; Xiaodong; Zhang; Qingfei

    2015-01-01

    Taking Shanghai Central City as its case study, this paper presents an approach to exploring the urban spatial structure through mobile phone positioning data. Firstly, based on base station location data and mobile phone signaling data, the paper analyses the number of users connecting to each base station, and further generates the maps of mobile phone user density through kernel density analysis. We move on to calculate the multi-day average user density based on a time frame of 10:00 and 23:00 at workdays and 15:00 and 23:00 at weekends for Shanghai Central City. Then, through spatial aggregation and density classifi cation on the density maps of 10:00 at workdays and 15:00 at weekends, we identify the ranks and functions of public centers within Shanghai Central City. Lastly, we identify residential areas, business off ice areas, and leisure areas in Shanghai Central City and measure the degree of functional mix by comparing the ratio of day and night user density as well as the user density at nighttime of workdays and weekends.

  19. Een oecologisch onderzoek over de appelbloedluis, Eriosoma lanigerum (Hausm.), en haar parasiet Aphelinus mali (Hald.) in Nederland

    NARCIS (Netherlands)

    Evenhuis, Hendrik Harmannus

    1958-01-01

    The woolly aphid is a serious apple pest. An account is given of the introduction of the woolly aphid parasite (Aphelinus mali) from N.-America into Europe and especially into the Netherlands form France by the Phytopahtological Service in 1924. The initial attempt to establish the insect in Wagenin

  20. Using modeling, satellite images and existing global datasets for rapid preliminary assessments of renewable energy resources: The case of Mali

    DEFF Research Database (Denmark)

    Nygaard, Ivan; Rasmussen, K.; Badger, Jake;

    2010-01-01

    This paper presents a novel approach to the preliminary, low-cost, national-scale mapping of wind energy, solar energy and certain categories of bio-energy resources in developing countries, using Mali as an example. The methods applied make extensive use of satellite remote sensing and meteorolo...

  1. Enhancing Community Knowledge and Health Behaviors to Eliminate Blinding Trachoma in Mali Using Radio Messaging as a Strategy

    Science.gov (United States)

    Bamani, Sanoussi; Toubali, Emily; Diarra, Sadio; Goita, Seydou; Berte, Zana; Coulibaly, Famolo; Sangare, Hama; Tuinsma, Marjon; Zhang, Yaobi; Dembele, Benoit; Melvin, Palesa; MacArthur, Chad

    2013-01-01

    The National Blindness Prevention Program in Mali has broadcast messages on the radio about trachoma as part of the country's trachoma elimination strategy since 2008. In 2011, a radio impact survey using multi-stage cluster sampling was conducted in the regions of Kayes and Segou to assess radio listening habits, coverage of the broadcasts,…

  2. Gestion de la fertilité des sols par classe d'exploitation au Mali-Sud

    NARCIS (Netherlands)

    Kante, S.

    2001-01-01

    In Southern Mali, it becomes increasingly difficult to take poor and overused arable land and pastures temporarily out of production, at a time when growing human and animal populations require increasing amounts for food and feed. In fact, the tendency is towards continuous cultivation, and as orga

  3. Economic and Social Sustainability Performance of Jatropha Projects: Results from Field Surveys in Mozambique, Tanzania and Mali

    NARCIS (Netherlands)

    Romijn, Henny; Heijnen, Sanne; Rom Colthoff, Jouke; de Jong, Boris; van Eijck, Janske

    2014-01-01

    This paper presents results from comprehensive field surveys of jatropha projects in Mozambique, Tanzania and Mali in 2012. The article singles out the salient economic and social impact results and derives lessons. The results clearly demonstrate the weak business case for jatropha biofuel producti

  4. Contemporary approaches to reducing the risks of central counterparties based on the use of marginal contributions

    Directory of Open Access Journals (Sweden)

    Utkin Viktor Sergeyevich

    2012-07-01

    Full Text Available To protect their own interests central counterparties has developed a number of procedures, including payment of guarantee margin by trading members as a means to ensure their positions. This article discusses a number of approaches, which attempt to simulate the risks of the Central Committee, as well as calculating the amount of margin and other resources in the event of insolvency. These approaches are based on the simulation of the three main types: (a statistical modeling; (b optimization modeling, and (c model of option pricing. The author incorporates the basic provisions of models.

  5. AphidBase: A centralized bioinformatic resource for annotation of the pea aphid genome

    OpenAIRE

    Legeai, Fabrice; Shigenobu, Shuji; Gauthier, Jean-Pierre; Colbourne, John; Rispe, Claude; Collin, Olivier; Richards, Stephen; Wilson, Alex C. C.; Tagu, Denis

    2010-01-01

    AphidBase is a centralized bioinformatic resource that was developed to facilitate community annotation of the pea aphid genome by the International Aphid Genomics Consortium (IAGC). The AphidBase Information System designed to organize and distribute genomic data and annotations for a large international community was constructed using open source software tools from the Generic Model Organism Database (GMOD). The system includes Apollo and GBrowse utilities as well as a wiki, blast search c...

  6. Anti-triangle centrality-based community detection in complex networks.

    Science.gov (United States)

    Jia, Songwei; Gao, Lin; Gao, Yong; Wang, Haiyang

    2014-06-01

    Community detection has been extensively studied in the past decades largely because of the fact that community exists in various networks such as technological, social and biological networks. Most of the available algorithms, however, only focus on the properties of the vertices, ignoring the roles of the edges. To explore the roles of the edges in the networks for community discovery, the authors introduce the novel edge centrality based on its antitriangle property. To investigate how the edge centrality characterises the community structure, they develop an approach based on the edge antitriangle centrality with the isolated vertex handling strategy (EACH) for community detection. EACH first calculates the edge antitriangle centrality scores for all the edges of a given network and removes the edge with the highest score per iteration until the scores of the remaining edges are all zero. Furthermore, EACH is characterised by being free of the parameters and independent of any additional measures to determine the community structure. To demonstrate the effectiveness of EACH, they compare it with the state-of-the art algorithms on both the synthetic networks and the real world networks. The experimental results show that EACH is more accurate and has lower complexity in terms of community discovery and especially it can gain quite inherent and consistent communities with a maximal diameter of four jumps. PMID:25014378

  7. THE INDEPENDENCE OF CENTRAL BANKS IN CENTRAL AND EASTERN EUROPE-A MONETARY POLICY STRATEGY BASED APPROACH

    Directory of Open Access Journals (Sweden)

    Popescu Iulian Vasile

    2013-06-01

    Full Text Available The present paper aims to examine the trends of the last decade and a half of central banks independence (CBI in Central and Eastern European countries on the road to the euro adoption and to compare the results with those identified in the case of the European Central Bank (ECB. We approached CBI from the perspective of monetary policy strategies central banks (CBs use. The main results show increasing independence during the selected time frame for all monetary authorities subject to analysis, regardless of the applied monetary policy strategy; superior average levels of CBI in CEE countries oriented to inflation targeting compared to those using the exchange rate as nominal anchor; higher degree of independence of ECB in relation to monetary authorities that use an inflation targeting strategy; the simultaneous presence of a significant level of independence, low inflation and stronger economic development in CEE members where CB is geared towards inflation targeting compared to CBs that implement a strategy of exchange rate targeting.

  8. [Activity of Save the Children (USA) in the cercle de Kolondieba. The transition toward better health in Mali].

    Science.gov (United States)

    Poulton, M

    1992-06-01

    Save the Children (STC) Federation set up a community development program in Kolondieba district, Mali, to improve the life of children through improving living conditions. It provides technical assistance and materials to the rural communities who participate in activities aiming to improve their socioeconomic condition. The program focuses on water resources; agriculture; credit, saving, and micro-enterprises; education and training; women in development; and health. The goal of the health component is educating families so that they adopt behaviors protecting the life and health of children and mothers. Home visits and training programs cover vaccination, preparation and use of oral rehydration solution, growth monitoring, nutrition and education, water sanitation, and prenatal care. STC established information systems based on the complete registration of the Kolondieba population. The program re-instituted rural maternity wards. Two months after nurses started going to the villages to conduct prenatal care and education activities, prenatal care visits at the health center increased. A massive immunization campaign covered women of reproductive age and children 0-6 years old. A mobile immunization team traveled from 1 community to another 3 times. The villagers witnessed proof that immunizations prevented target diseases and that children no longer died. The first activity taken up by STC in Kolondieba concerned water resources. 15 teams used relatively simple and inexpensive techniques to drill and build wells. They built at least 1 well per village. Wells are now a source of pride and joy for the villagers, who take good care of the wells. Villagers have a strong sense of ownership and responsibility for community welfare. Due to community participation and decision-making, this development program is sustainable. PMID:12344638

  9. Nutrient composition and nutritional importance of green leaves and wild food resources in an agricultural district, Koutiala, in southern Mali.

    Science.gov (United States)

    Nordeide, M B; Hatløy, A; Følling, M; Lied, E; Oshaug, A

    1996-11-01

    This paper discusses the nutrient composition and the nutritional importance of green leaves and wild gathered foods in an area with surplus food production in Mali. In this West African country, there is little information about the nutrient composition and the nutritional quality of foods in general, and of wild gathered foods in particular. Food frequency was collected in two cross-sectional surveys. Focus group discussions with women in the area were used to collect information about seasonality, availability and preparation of various foods. Selected food samples were collected for chemical analysis of nutrient composition. The food samples of green leaves (Adansonia digitata, Amaranthus viridis, Tamarindus indica, Allium cepa), seeds and flour (Parkia biglobosa) and fruits (Tamarindus indica) were analysed for water, energy, fat, protein, minerals, amino acids and carotenoids. Availability and use of the foods varied with seasons. In the rainy season, wild gathered foods (e.g. A. digitata) were used as much as fresh cultivated foods (e.g., A. viridis and A. cepa). The wild food resources were more frequently used in rural than in urban areas, with A. digitata as the dominating green leaves. Green leaves were rich in energy, protein and minerals (calcium, iron). Leaves of A. viridis were, in particular, rich in beta-carotene (3290 micrograms/100 g). Chemical score in dried green leaves varied from 47 (A. cepa) to 81 (A. digitata), with lysine as the first limiting amino acid. P. biglobosa fermented seeds, with 35% fat and 37% protein were a complementary source of lysine in the diet. Based on the seasonality, the frequency of use and the nutrient contents of selected green leaves and wild gathered foods in Koutiala district, it is concluded that these traditional and locally produced foods are valuable and important nutrient contributors in the diet both in rural and urban areas, but most important in rural areas.

  10. Central Nervous System Based Computing Models for Shelf Life Prediction of Soft Mouth Melting Milk Cakes

    Directory of Open Access Journals (Sweden)

    Gyanendra Kumar Goyal

    2012-04-01

    Full Text Available This paper presents the latency and potential of central nervous system based system intelligent computer engineering system for detecting shelf life of soft mouth melting milk cakes stored at 10o C. Soft mouth melting milk cakes are exquisite sweetmeat cuisine made out of heat and acid thickened solidified sweetened milk. In today’s highly competitive market consumers look for good quality food products. Shelf life is a good and accurate indicator to the food quality and safety. To achieve good quality of food products, detection of shelf life is important. Central nervous system based intelligent computing model was developed which detected 19.82 days shelf life, as against 21 days experimental shelf life.

  11. Central Nervous System Based Computing Models for Shelf Life Prediction of Soft Mouth Melting Milk Cakes

    OpenAIRE

    Gyanendra Kumar Goyal; Sumit Goyal

    2012-01-01

    This paper presents the latency and potential of central nervous system based system intelligent computer engineering system for detecting shelf life of soft mouth melting milk cakes stored at 10o C. Soft mouth melting milk cakes are exquisite sweetmeat cuisine made out of heat and acid thickened solidified sweetened milk. In today’s highly competitive market consumers look for good quality food products. Shelf life is a good and accurate indicator to the food quality and safety. To achieve g...

  12. Rural-Urban Transition in Central Java: Population and Economic Structural Changes Based on Cluster Analysis

    OpenAIRE

    Wiwandari Handayani

    2013-01-01

    In Central Java, in addition to the traditional view of urban transition as an aspect of urban industrialization, rural industrialization based on small- to medium-sized enterprises has become a concern, at least since the Indonesian economic crisis in 1997. Combinations of typical urban and rural activities have resulted in certain features of rural-urban transition as the urban population has continued to increase notably. The intention of this paper is to examine how rural-urban transition...

  13. An Agent-Based Model of Centralized Institutions, Social Network Technology, and Revolution

    OpenAIRE

    Makowsky, Michael D.; Jared Rubin

    2011-01-01

    Recent uprisings in the Arab world consist of individuals revealing vastly different preferences than were expressed prior to the uprisings. This paper sheds light on the general mechanisms underlying large-scale social and institutional change. We employ an agent-based model to test the impact of authority centralization and social network technology on preference revelation and falsification, social protest, and institutional change. We find that the amount of social and institutional chang...

  14. Mathematical Modeling of a developed Central Receiver Based on Evacuated Solar Tubes

    OpenAIRE

    Ali Basil. H.; Gilani S. I.; Al-Kayiem Hussain H.

    2016-01-01

    Solar central receiver plays a considerable role in the plant output power; it is one of the most important synthesis in the solar power tower plants. Its performance directly affects the efficiency of the entire solar power generation system. In this study, a new designed receiver model based on evacuated solar tube was proposed, and the dynamic characteristics of the developed receiver were investigated. In order to optimise and evaluate the dynamic characteristics of solar power plant comp...

  15. CrisprGE: a central hub of CRISPR/Cas-based genome editing

    OpenAIRE

    Kaur, Karambir; Tandon, Himani; Gupta, Amit Kumar; Kumar, Manoj

    2015-01-01

    CRISPR system is a powerful defense mechanism in bacteria and archaea to provide immunity against viruses. Recently, this process found a new application in intended targeting of the genomes. CRISPR-mediated genome editing is performed by two main components namely single guide RNA and Cas9 protein. Despite the enormous data generated in this area, there is a dearth of high throughput resource. Therefore, we have developed CrisprGE, a central hub of CRISPR/Cas-based genome editing. Presently,...

  16. Noms de personne et expression des ambitions matrimoniales chez les Bwa du Mali

    OpenAIRE

    Leguy, Cécile

    2008-01-01

    Que nous apprennent les noms de personne dans un contexte où la nomination peut être perçue comme un moyen d’expression subtil d’opinions qui ne sauraient se dire explicitement ? À partir d’un sujet de préoccupation fortement présent dans les messages des noms portés par les Bwa du Mali, le mariage, nous verrons comment l’anthropologue, attentif au contexte de la nomination et à l’identité du donneur de nom, peut accéder à une autre dimension de la vie sociale, au-delà des pratiques et des di...

  17. Genetic differentiation of watermelon landrace types in Mali revealed by microsatellite (SSR) markers

    DEFF Research Database (Denmark)

    Nantoume, Aminata Dolo; Andersen, Sven Bode; Jensen, Brita Dahl

    2013-01-01

    This study describes the genetic differentiation of a collection of 134 watermelon landrace accessions from Mali, representing red fleshed dessert and white fleshed seed and cooking type watermelons from five regions, plus three commercial dessert type cultivars with red flesh. The material...... the accessions into use groups (dessert, cooking, seed processing) explained 25 % of the variation. When categorising the accessions further into 10 landrace types, differentiated on the basis of use groups, local accession name, flesh colour and seed phenotype, these landrace types explained 26...... % of the variation. Analysis with the software Structure revealed that the accessions with confidence could be separated into two major genetic groups, related to flesh colour (red and white) of the watermelon fruits. The same analysis further indicated that the material may be differentiated into eight genetic sub...

  18. Fuelwood production of wooded savanna fallows in the Sudan zone of Mali

    Energy Technology Data Exchange (ETDEWEB)

    Ohler, F.M.J.

    1985-01-01

    The characteristics of a fallow farming system in the Sudan zone of Mali are outlined. Sorghum and bulrush millet are the staple crops and groundnuts are the cash crop. On average 7 trees are kept per ha (crown cover 7%), of which 60% are sheabutter trees (Vitellaria paradoxa). Various productive and environmental functions of fallow periods are pointed out. Fallow vegetation succession is described and data presented on the shrub layer structure (mainly coppice) and wood production in relation to grazing intensity; 30-50% of the fuelwood consumption of small-scale farmers can be suppled by their fallows. The functions of fallow will need to be replicated in modernized farming systems. 21 references.

  19. Development of a Physiologically-Based Pharmacokinetic Model of the Rat Central Nervous System

    Directory of Open Access Journals (Sweden)

    Raj K. Singh Badhan

    2014-03-01

    Full Text Available Central nervous system (CNS drug disposition is dictated by a drug’s physicochemical properties and its ability to permeate physiological barriers. The blood–brain barrier (BBB, blood-cerebrospinal fluid barrier and centrally located drug transporter proteins influence drug disposition within the central nervous system. Attainment of adequate brain-to-plasma and cerebrospinal fluid-to-plasma partitioning is important in determining the efficacy of centrally acting therapeutics. We have developed a physiologically-based pharmacokinetic model of the rat CNS which incorporates brain interstitial fluid (ISF, choroidal epithelial and total cerebrospinal fluid (CSF compartments and accurately predicts CNS pharmacokinetics. The model yielded reasonable predictions of unbound brain-to-plasma partition ratio (Kpuu,brain and CSF:plasma ratio (CSF:Plasmau using a series of in vitro permeability and unbound fraction parameters. When using in vitro permeability data obtained from L-mdr1a cells to estimate rat in vivo permeability, the model successfully predicted, to within 4-fold, Kpuu,brain and CSF:Plasmau for 81.5% of compounds simulated. The model presented allows for simultaneous simulation and analysis of both brain biophase and CSF to accurately predict CNS pharmacokinetics from preclinical drug parameters routinely available during discovery and development pathways.

  20. Decentralized State Estimation Algorithm of Centralized Equivalent Precision for Formation Flying Spacecrafts Based on Junction Tree

    Directory of Open Access Journals (Sweden)

    Mengyuan Dai

    2015-01-01

    Full Text Available As centralized state estimation algorithms for formation flying spacecraft would suffer from high computational burdens when the scale of the formation increases, it is necessary to develop decentralized algorithms. To the state of the art, most decentralized algorithms for formation flying are derived from centralized EKF by simplification and decoupling, rendering suboptimal estimations. In this paper, typical decentralized state estimation algorithms are reviewed, and a new scheme for decentralized algorithms is proposed. In the new solution, the system is modeled as a dynamic Bayesian network (DBN. A probabilistic graphical method named junction tree (JT is used to analyze the hidden distributed structure of the DBNs. Inference on JT is a decentralized form of centralized Bayesian estimation (BE, which is a modularized three-step procedure of receiving messages, collecting evidences, and generating messages. As KF is a special case of BE, the new solution based on JT is equivalent in precision to centralized KF in theory. A cooperative navigation example of a three-satellite formation is used to test the decentralized algorithms. Simulation results indicate that JT has the best precision among all current decentralized algorithms.

  1. Active trachoma among children in Mali: Clustering and environmental risk factors.

    Directory of Open Access Journals (Sweden)

    Mathieu Hägi

    Full Text Available BACKGROUND: Active trachoma is not uniformly distributed in endemic areas, and local environmental factors influencing its prevalence are not yet adequately understood. Determining whether clustering is a consistent phenomenon may help predict likely modes of transmission and help to determine the appropriate level at which to target control interventions. The aims of this study were, therefore, to disentangle the relative importance of clustering at different levels and to assess the respective role of individual, socio-demographic, and environmental factors on active trachoma prevalence among children in Mali. METHODOLOGY/PRINCIPAL FINDINGS: We used anonymous data collected during the Mali national trachoma survey (1996-1997 at different levels of the traditional social structure (14,627 children under 10 years of age, 6,251 caretakers, 2,269 households, 203 villages. Besides field-collected data, environmental variables were retrieved later from various databases at the village level. Bayesian hierarchical logistic models were fit to these prevalence and exposure data. Clustering revealed significant results at four hierarchical levels. The higher proportion of the variation in the occurrence of active trachoma was attributable to the village level (36.7%, followed by household (25.3%, and child (24.7% levels. Beyond some well-established individual risk factors (age between 3 and 5, dirty face, and flies on the face, we showed that caretaker-level (wiping after body washing, household-level (common ownership of radio, and motorbike, and village-level (presence of a women's association, average monthly maximal temperature and sunshine fraction, average annual mean temperature, presence of rainy days features were associated with reduced active trachoma prevalence. CONCLUSIONS/SIGNIFICANCE: This study clearly indicates the importance of directing control efforts both at children with active trachoma as well as those with close contact, and at

  2. The Hidden Costs of a Free Caesarean Section Policy in West Africa (Kayes Region, Mali).

    Science.gov (United States)

    Ravit, Marion; Philibert, Aline; Tourigny, Caroline; Traore, Mamadou; Coulibaly, Aliou; Dumont, Alexandre; Fournier, Pierre

    2015-08-01

    The fee exemption policy for EmONC in Mali aims to lower the financial barrier to care. The objective of the study was to evaluate the direct and indirect expenses associated with caesarean interventions performed in EmONC and the factors associated with these expenses. Data sampling followed the case control approach used in the large project (deceased and near-miss women). Our sample consisted of a total of 190 women who underwent caesarean interventions. Data were collected from the health workers and with a social approach by administering questionnaires to the persons who accompanied the woman. Household socioeconomic status was assessed using a wealth index constructed with a principal component analysis. The factors significantly associated with expenses were determined using multivariate linear regression analyses. Women in the Kayes region spent on average 77,017 FCFA (163 USD) for a caesarean episode in EmONC, of which 70 % was for treatment. Despite the caesarean fee exemption, 91 % of the women still paid for their treatment. The largest treatment-related direct expenses were for prescriptions, transfusion, antibiotics, and antihypertensive medication. Near-misses, women who presented a hemorrhage or an infection, and/or women living in rural areas spent significantly more than the others. Although abolishing fees of EmONC in Mali plays an important role in reducing maternal death by increasing access to caesarean sections, this paper shows that the fee policy did not benefit to all women. There are still barriers to EmONC access for women of the lowest socio-economic group. These included direct expenses for drugs prescription, treatment and indirect expenses for transport and food. PMID:25874875

  3. Remote sensing and environment in the study of the malaria vector Anopheles gambiae in Mali

    Science.gov (United States)

    Rian, Sigrid Katrine Eivindsdatter

    The malaria mosquito Anopheles gambiae is the most important vector for the most devastating form of human malaria, the parasite Plasmodium falciparum. In-depth knowledge of the vector's history and environmental preferences is essential in the pursuit of new malaria mitigation strategies. Research was conducted in Mali across a range of habitats occupied by the vector, focusing on three identified chromosomal forms in the mosquito complex. The development of a 500-m landcover classification map was carried out using MODIS satellite imagery and extensive ground survey. The resulting product has the highest resolution and is the most up-to-date and most extensively ground-surveyed among land-cover maps for the study region. The new landcover classification product is a useful tool in the mapping of the varying ecological preferences of the different An. gambiae chromosomal forms. Climate and vegetation characteristics and their relationship to chromosomal forms were investigated further along a Southwest-Northeast moisture gradient in Mali. This research demonstrates particular ecological preferences of each chromosomal form, and gives a detailed examination of particular vegetation structural and climatological patterns across the study region. A key issue in current research into the population structure of An. gambiae is speciation and evolution in the complex, as an understanding of the mechanisms of change can help in the development of new mitigation strategies. A historical review of the paleoecology, archaeology, and other historical sources intended to shed light on the evolutionary history of the vector is presented. The generally held assumption that the current breed of An. gambiae emerged in the rainforest is called into question and discussed within the framework of paleoenvironment and human expansions in sub-Saharan West Africa.

  4. Climate change and human health: Spatial modeling of water availability, malnutrition, and livelihoods in Mali, Africa

    Science.gov (United States)

    Jankowska, M.M.; Lopez-Carr, D.; Funk, C.; Husak, G.J.; Chafe, Z.A.

    2012-01-01

    This study develops a novel approach for projecting climate trends in the Sahel in relation to shifting livelihood zones and health outcomes. Focusing on Mali, we explore baseline relationships between temperature, precipitation, livelihood, and malnutrition in 407 Demographic and Health Survey (DHS) clusters with a total of 14,238 children, resulting in a thorough spatial analysis of coupled climate-health dynamics. Results suggest links between livelihoods and each measure of malnutrition, as well as a link between climate and stunting. A 'front-line' of vulnerability, related to the transition between agricultural and pastoral livelihoods, is identified as an area where mitigation efforts might be usefully targeted. Additionally, climate is projected to 2025 for the Sahel, and demographic trends are introduced to explore how the intersection of climate and demographics may shift the vulnerability 'front-line', potentially exposing an additional 6 million people in Mali, up to a million of them children, to heightened risk of malnutrition from climate and livelihood changes. Results indicate that, holding constant morbidity levels, approximately one quarter of a million children will suffer stunting, nearly two hundred thousand will be malnourished, and over one hundred thousand will become anemic in this expanding arid zone by 2025. Climate and health research conducted at finer spatial scales and within shorter projected time lines can identify vulnerability hot spots that are of the highest priority for adaptation interventions; such an analysis can also identify areas with similar characteristics that may be at heightened risk. Such meso-scale coupled human-environment research may facilitate appropriate policy interventions strategically located beyond today's vulnerability front-line. ?? 2011 Elsevier Ltd.

  5. The efficacy of centralized flow rate control in 802.11-based wireless mesh networks

    KAUST Repository

    Jamshaid, K.

    2013-06-13

    Commodity WiFi-based wireless mesh networks (WMNs) can be used to provide last mile Internet access. These networks exhibit extreme unfairness with backlogged traffic sources. Current solutions propose distributed source-rate control algorithms requiring link-layer or transport-layer changes on all mesh nodes. This is often infeasible in large practical deployments. In wireline networks, router-assisted rate control techniques have been proposed for use alongside end-to-end mechanisms. We wish to evaluate the feasibility of establishing similar centralized control via gateways in WMNs. In this paper, we focus on the efficacy of this control rather than the specifics of the controller design mechanism. We answer the question: Given sources that react predictably to congestion notification, can we enforce a desired rate allocation through a single centralized controller? The answer is not obvious because flows experience varying contention levels, and transmissions are scheduled by a node using imperfect local knowledge. We find that common router-assisted flow control schemes used in wired networks fail in WMNs because they assume that (1) links are independent, and (2) router queue buildups are sufficient for detecting congestion. We show that non-work-conserving, rate-based centralized scheduling can effectively enforce rate allocation. It can achieve results comparable to source rate limiting, without requiring any modifications to mesh routers or client devices. 2013 Jamshaid et al.; licensee Springer.

  6. Central-force decomposition of spline-based modified embedded atom method potential

    Science.gov (United States)

    Winczewski, S.; Dziedzic, J.; Rybicki, J.

    2016-10-01

    Central-force decompositions are fundamental to the calculation of stress fields in atomic systems by means of Hardy stress. We derive expressions for a central-force decomposition of the spline-based modified embedded atom method (s-MEAM) potential. The expressions are subsequently simplified to a form that can be readily used in molecular-dynamics simulations, enabling the calculation of the spatial distribution of stress in systems treated with this novel class of empirical potentials. We briefly discuss the properties of the obtained decomposition and highlight further computational techniques that can be expected to benefit from the results of this work. To demonstrate the practicability of the derived expressions, we apply them to calculate stress fields due to an edge dislocation in bcc Mo, comparing their predictions to those of linear elasticity theory.

  7. Evidence-based measures to prevent central line-associated bloodstream infections: a systematic review 1

    Science.gov (United States)

    Perin, Daniele Cristina; Erdmann, Alacoque Lorenzini; Higashi, Giovana Dorneles Callegaro; Sasso, Grace Teresinha Marcon Dal

    2016-01-01

    ABSTRACT Objective: to identify evidence-based care to prevent CLABSI among adult patients hospitalized in ICUs. Method: systematic review conducted in the following databases: PubMed, Scopus, Cinahl, Web of Science, Lilacs, Bdenf and Cochrane Studies addressing care and maintenance of central venous catheters, published from January 2011 to July 2014 were searched. The 34 studies identified were organized in an instrument and assessed by using the classification provided by the Joanna Briggs Institute. Results: the studies presented care bundles including elements such as hand hygiene and maximal barrier precautions; multidimensional programs and strategies such as impregnated catheters and bandages and the involvement of facilities in and commitment of staff to preventing infections. Conclusions: care bundles coupled with education and the commitment of both staff and institutions is a strategy that can contribute to decreased rates of central line-associated bloodstream infections among adult patients hospitalized in intensive care units. PMID:27598378

  8. Sulcus-based MR analysis of focal cortical dysplasia located in the central region.

    Directory of Open Access Journals (Sweden)

    Pauline Roca

    Full Text Available Focal cortical dysplasias (FCDs are mainly located in the frontal region, with a particular tropism for the central sulcus. Up to 30% of lesions are undetected (magnetic resonance [MR]-negative FCD patients or belatedly diagnosed by visual analysis of MR images. We propose an automated sulcus-based method to analyze abnormal sulcal patterns associated with central FCD, taking into account the normal interindividual sulcal variability.We retrospectively studied 29 right-handed patients with FCD in the central region (including 12 MR negative histologically-confirmed cases and 29 right-handed controls. The analysis of sulcal abnormalities from T1-weighted MR imaging (MRI was performed using a graph-based representation of the cortical folds and an automated sulci recognition system, providing a new quantitative criterion to describe sulcal patterns, termed sulcus energy.Group analysis showed that the central sulcus in the hemisphere ipsilateral to the FCD exhibited an abnormal sulcal pattern compared with controls (p = 0.032. FCDs were associated with abnormal patterns of the central sulci compared with controls (p = 0.006, a result that remained significant when MR-negative and MR-positive patients were considered separately, while the effects of sex, age and MR-field were not significant. At the individual level, sulcus energy alone failed to detect the FCD lesion. We found, however, a significant association between maximum z-scores and the site of FCD (p = 0.0046 which remained significant in MR-negative (p = 0.024 but not in MR-positive patients (p = 0.058. The maximum z-score pointed to an FCD sulcus in four MR-negative and five MR-positive patients.We identified abnormal sulcal patterns in patients with FCD of the central region compared with healthy controls. The abnormal sulcal patterns ipsilateral to the FCD and the link between sulcus energy and the FCD location strengthen the interest of sulcal abnormalities in FCD patients.

  9. Socio-political Turmoil in Mali: The Public Debate Following the Coup d’État on 22 March 2012 Sozio-politische Turbulenzen in Mali: Die öffentliche Debatte nach dem Staatsstreich vom 22. März 2012

    Directory of Open Access Journals (Sweden)

    Sten Hagberg

    2012-01-01

    Full Text Available During the night between 21 and 22 March 2012, a group of young military officers overthrew Mali’s president, Amadou Toumani Touré. The group justified the coup by citing the inability of the regime to both deal with the crisis in the North and provide the army with the appropriate material and manpower to defend the national territory. The coup plunged Mali into violence, and caused a de facto partition of the country. The socio-political turmoil pitting different political and armed factions against each other has continued unabated and has been accompanied by intense mass media debates. In this report we focus on the Malian public debate. By looking at the political class, the international community, and the partition of the country, we analyse representations and stereotypes prevailing in this debate.In der Nacht vom 21. zum 22. März 2012 wurde der Präsident Malis, Amadou Toumani Touré, durch eine Gruppe junger Offiziere gestürzt. Die Gruppe rechtfertigte den Putsch, indem sie auf die Unfähigkeit des Regimes verwies, die Krise im Norden zu bewältigen und die Armee personell und materiell angemessen auszustatten, um die Grenzen das Landes verteidigen zu können. Der Staatsstreich stürzte Mali in eine gewaltsame Auseinandersetzung und führte zu einer faktischen Teilung des Landes. Die sozio-politischen Turbulenzen, in denen verschiedene politische und bewaffnete Gruppierungen gegeneinander antraten, haben seither unvermindert angehalten und wurden von intensiven Debatten in den Massenmedien begleitet. Der vorliegende Bericht konzentriert sich auf die öffentliche Debatte in Mali. Vor dem Hintergrund der politischen Entwicklung des Landes, der Positionen der internationalen Gemeinschaft und der Ursachen für die Teilung des Landes stellen die Autoren die Darstellungsweisen und Stereotypen dar, die in dieser Debatte Verwendung finden.

  10. Mali: le règlement se fera à l'échelle régionale

    OpenAIRE

    Giraut, Frédéric; Elhadji Moutari, Maman

    2013-01-01

    Le spectre du conflit intercommunautaire est bien là au Mali avec la suspicion d'exactions à l'encontre de «peaux claires» (Touaregs, Arabes et autres) dans les villes libérées de l'emprise islamiste. Cette suspicion porte sur l'armée malienne et non sur les populations arrière où aucun clash communautaire n'a été signalé depuis le début du conflit. Dans ce contexte, des experts redoutent l'embrasement et préconisent non seulement un règlement politique de la question touareg au Mali (nécessa...

  11. Selection, efficacy, ecological characterization and formulation of fungal control agents against water hyacinth [Eichhornia crassipes (Martius) Solms] in Mali

    OpenAIRE

    Dagno, Karim

    2011-01-01

    Rice and irrigated orchards are considered as the most important food and economical sources in Mali, which watered from Niger River. However, stable productions of rice and orchards products have been limited by many disease, insects, and weeds. Recently, water hyacinth infestation in river of Niger has increased drastically and as affected by the decrease of water flow due to clogging dams and irrigation work. Biological control of weeds is an alternative approach to chemical herbicide use,...

  12. Water management and water harvesting: how to overcome constraints in community gardening in semi-arid Mali

    OpenAIRE

    Bass, Hans-Heinrich; Freyhold, Klaus von; Weisskoeppel, Cordula

    2013-01-01

    Malnutrition, i.e. the undersupply of micro-nutrients, is a common phenomenon in the villages of West African Mali. Community gardening can help to overcome the gap between supply of and requirements for micro-nutrients. In addition to its effect on nutrition, community gardening supports the pro-poor orientation of economic growth, and has a potentially positive effect on human capital formation, communal coherence, and women’s empowerment. Water supply, however, is a major bottleneck for ga...

  13. The Impact of the Increase in Food Prices on Child Poverty and the Policy Response in Mali

    OpenAIRE

    Sami Bibi; John Cockburn; Massa Coulibaly; Luca Tiberti

    2009-01-01

    Since 2006, Mali has experienced the full effects of the global food crisis, with price increases of up to 67%. This study presents simulations of the impacts of this crisis and a number of policy responses with respect to the welfare of children. The impacts are analyzed in terms of monetary (food) poverty, nutrition, education, child labour and access to health services of children. According to simulations, food poverty among children would have increased from 41% to 51%, with a correspond...

  14. Electric protections based in microprocessors in power plants; Protecciones electricas basadas en microprocesadores en centrales generadoras

    Energy Technology Data Exchange (ETDEWEB)

    Libreros, Domitilo; Castanon Jimenez, Jose Ismael [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1987-12-31

    This article is centered around the substitution of the conventional electric protections of a power plant in connection type unit for protections based in microprocessors. A general model of conventional protection of a power plant is described and the number of analogic and digital signals that intervene in that model are quantified. A model is setup for power plant protection with microprocessors, analyzing each one of the modules that would form it. Finally, the algorithms to carry on such protection are presented. [Espanol] Este articulo se centra en torno a la sustitucion de las protecciones electricas convencionales de una central generadora en conexion tipo unidad por protecciones basadas en microprocesadores. Se describe el modelo general de proteccion convencional de una central generadora y se cuantifica el numero de senales analogicas y digitales que interviene en dicho modelo. Se propone un modelo para proteccion de centrales generadoras mediante microprocesadores, analizandose cada uno de los modulos que lo conformarian. Finalmente, se presentan los algoritmos para realizar dicha proteccion.

  15. Cluster-based centralized data fusion for tracking maneuvering targets using interacting multiple model algorithm

    Indian Academy of Sciences (India)

    V Vaidehi; K Kalavidya; S Indira Gandhi

    2004-04-01

    The interacting multiple model (IMM) algorithm has proved to be useful in tracking maneuvering targets. Tracking accuracy can be further improved using data fusion. Tracking of multiple targets using multiple sensors and fusing them at a central site using centralized architecture involves communication of large volumes of measurements to a common site. This results in heavy processing requirement at the central site. Moreover, track updates have to be obtained in the fusion centre before the next measurement arrives. For solving this computational complexity, a cluster-based parallel processing solution is presented in this paper. In this scheme, measurements are sent to the data fusion centre where the measurements are partitioned and given to the slave processors in the cluster. The slave processors use the IMM algorithm to get accurate updates of the tracks. The master processor collects the updated tracks and performs data fusion using ‘weight decision approach’. The improvement in the computation time using clusters in the data fusion centre is presented in this paper.

  16. High-order central Hermite WENO schemes: Dimension-by-dimension moment-based reconstructions

    Science.gov (United States)

    Tao, Zhanjing; Li, Fengyan; Qiu, Jianxian

    2016-08-01

    In this paper, a class of high-order central finite volume schemes is proposed for solving one- and two-dimensional hyperbolic conservation laws. Formulated on staggered meshes, the methods involve Hermite WENO (HWENO) spatial reconstructions, and Lax-Wendroff type discretizations or the natural continuous extension of Runge-Kutta methods in time. Differently from the central Hermite WENO methods we developed previously in Tao et al. (2015) [34], the spatial reconstructions, a core ingredient of the methods, are based on the zeroth-order and the first-order moments of the solution, and are implemented through a dimension-by-dimension strategy when the spatial dimension is higher than one. This leads to much simpler implementation of the methods in higher dimension and better cost efficiency. Meanwhile, the proposed methods have the attractive features of the general central Hermite WENO methods such as being compact in reconstruction and requiring neither flux splitting nor numerical fluxes, while being accurate and essentially non-oscillatory. A collection of one- and two-dimensional numerical examples is presented to demonstrate high resolution and robustness of the methods in capturing smooth and non-smooth solutions.

  17. SOTER-based soil parameter estimates for Central Africa - DR of Congo, Burundi and Rwanda (ver. 1.0)

    NARCIS (Netherlands)

    Batjes, N.H.

    2014-01-01

    This harmonized set of soil parameter estimates for Central Africa, comprising Burundi, the Democratic Republic of the Congo and Rwanda, was derived from the Soil and Terrain Database for Central Africa (SOTERCAF ver. 1.0) and the ISRIC-WISE soil profile database, using standardized taxonomy-based p

  18. Palaeocology of coal-bearing Eocene sediments in central Anatolia (Turkey) based on quantitative palynological data

    Energy Technology Data Exchange (ETDEWEB)

    Akkiraz, M.S.; Kayseri, M.S.; Akgun, F. [Dokuz Eylul University, Izmir (Turkey). Dept. of Geological Engineering

    2008-04-15

    In this study, the lignite-bearing Yoncali formation between Yozgat and Sorgun, in central Anatolia has been palynologically examined. Based on 37 outcrop samples, quantitative palynological studies recognized 64 genera and 136 palynoflora species in the palynological assemblage, which indicated a Middle-Late Eocene age. This paper also presents a quantitative palaeovegetation and palaeoclimate reconstruction for the Middle-Upper Eocene coal occurrences of Central Anatolia on the basis of palynomorph assemblages. The diversified floral and ecological characteristics of the pollen taxa indicates that the Middle-Upper Eocene formations in central Anatolia were characterized by the presence of a complex mangrove swamp with contributions by Nypa, Pelliciera, Avicennia, Diporites tszkaszentgydrgyi and dinoflagellate cysts which reflect warm climatic conditions. Lowland-riparian and montane elements are characterized by the dominance of Myricaceae, Symplocaceae, Icacinaceae, Quercus, Pinus and Castanea. Swamp-freshwater elements are represented by Sparganjaceae, Nymphaceae, Taxodjaceae, Cupressaceae and Nyssa as well as fern spores such as Osmundaceae and Gleicheniaceae. The calculations were performed with the help of the 'Coexistence Approach' method to climatically evaluate palynoflora from the Yozgat-Sorgun area. The obtained results have been compared to data derived from the application of the Coexistence Approach to other, already published Central Anatolian palynofloras of the same age. The results of the climatic inferences suggest that the palaeoclimatic conditions were in the megathermal zone, megatherm/mesotherm intermediate zone whereas mesothermic conditions prevailed in the montane region. Likewise, the results of mean annual range of temperatures indicate the influence of the Indian ocean, which enabled the development of the mangroves.

  19. Modeling infection transmission in primate networks to predict centrality-based risk.

    Science.gov (United States)

    Romano, Valéria; Duboscq, Julie; Sarabian, Cécile; Thomas, Elodie; Sueur, Cédric; MacIntosh, Andrew J J

    2016-07-01

    Social structure can theoretically regulate disease risk by mediating exposure to pathogens via social proximity and contact. Investigating the role of central individuals within a network may help predict infectious agent transmission as well as implement disease control strategies, but little is known about such dynamics in real primate networks. We combined social network analysis and a modeling approach to better understand transmission of a theoretical infectious agent in wild Japanese macaques, highly social animals which form extended but highly differentiated social networks. We collected focal data from adult females living on the islands of Koshima and Yakushima, Japan. Individual identities as well as grooming networks were included in a Markov graph-based simulation. In this model, the probability that an individual will transmit an infectious agent depends on the strength of its relationships with other group members. Similarly, its probability of being infected depends on its relationships with already infected group members. We correlated: (i) the percentage of subjects infected during a latency-constrained epidemic; (ii) the mean latency to complete transmission; (iii) the probability that an individual is infected first among all group members; and (iv) each individual's mean rank in the chain of transmission with different individual network centralities (eigenvector, strength, betweenness). Our results support the hypothesis that more central individuals transmit infections in a shorter amount of time and to more subjects but also become infected more quickly than less central individuals. However, we also observed that the spread of infectious agents on the Yakushima network did not always differ from expectations of spread on random networks. Generalizations about the importance of observed social networks in pathogen flow should thus be made with caution, since individual characteristics in some real world networks appear less relevant than

  20. QUARITE (quality of care, risk management and technology in obstetrics: a cluster-randomized trial of a multifaceted intervention to improve emergency obstetric care in Senegal and Mali

    Directory of Open Access Journals (Sweden)

    Gaye Alioune

    2009-09-01

    Full Text Available Abstract Background Maternal and perinatal mortality are major problems for which progress in sub-Saharan Africa has been inadequate, even though childbirth services are available, even in the poorest countries. Reducing them is the aim of two of the main Millennium Development Goals. Many initiatives have been undertaken to remedy this situation, such as the Advances in Labour and Risk Management (ALARM International Program, whose purpose is to improve the quality of obstetric services in low-income countries. However, few interventions have been evaluated, in this context, using rigorous methods for analyzing effectiveness in terms of health outcomes. The objective of this trial is to evaluate the effectiveness of the ALARM International Program (AIP in reducing maternal mortality in referral hospitals in Senegal and Mali. Secondary goals include evaluation of the relationships between effectiveness and resource availability, service organization, medical practices, and satisfaction among health personnel. Methods/Design This is an international, multi-centre, controlled cluster-randomized trial of a complex intervention. The intervention is based on the concept of evidence-based practice and on a combination of two approaches aimed at improving the performance of health personnel: 1 Educational outreach visits; and 2 the implementation of facility-based maternal death reviews. The unit of intervention is the public health facility equipped with a functional operating room. On the basis of consent provided by hospital authorities, 46 centres out of 49 eligible were selected in Mali and Senegal. Using randomization stratified by country and by level of care, 23 centres will be allocated to the intervention group and 23 to the control group. The intervention will last two years. It will be preceded by a pre-intervention one-year period for baseline data collection. A continuous clinical data collection system has been set up in all

  1. Structural analysis of the central Columbia Plateau utilizing radar, digital topography, and magnetic data bases

    International Nuclear Information System (INIS)

    Interest in the Hanford site (Washington) as a nuclear production, power, and waste disposal site has led to generation of a vast quantity of geophysical and remote sensing data sets of the central Columbia Plateau. To data, these various studies, including at least 13 independent magnetic linear and image lineament studies, have not been adequately correlated. Therefore, these studies provide a unique opportunity to compare and contrast the viability of the different geophysical and remote sensing techniques. The geology of the central Columbia Plateau is characterized by subdued topography and limited outcrop, with most of the exposure concentrated in localized folded/faulted mountains (the Yakima folds) and along river canyons. In order to efficiently compare lineament data bases, we have written an automated computer routine that correlated lineaments that are within a user specified distance of each other. The angle between their trends has to be less than an input maximum separation angle. If more than two lineament maps exist for the area, the analyst may also specify the minimum number of times each structure must be seen. The lineament correlation routine was applied to data bases of all aeromagnetic linears as well as lineaments seen on radar and a digital elevation model DEM image. Geologic structures align with a set of three-dimensional planar structures identified with our Geologic Spatial Analysis (GSA) system. The GSA analysis is based upon computer automated detection of valley bottoms as defined by a DEM

  2. IMPLEMENTATION OF CENTRAL QUEUE BASED REALTIME SCHEDULER FOR MULTIPLE SOURCE DATA STREAMING

    Directory of Open Access Journals (Sweden)

    V. Kaviha

    2014-01-01

    Full Text Available Real-time data packet sources are required to remain robust against different security threats. This study proposes a real-time secure scheduling strategy for data transmission to enhance the communication throughput and reduce the overheads. The proposed system combines real-time scheduling with security service enhancement, error detection and realtime scheduler based on EDF algorithm using uc/os-II real time operating system, implemented on cortex M3 processor. The scheduling unit uses central queue management model and the security enhancement scheme adopts a blowfish encryption mechanism.

  3. Central FPGA-based destination and load control in the LHCb MHz event readout

    Science.gov (United States)

    Jacobsson, R.

    2012-10-01

    The readout strategy of the LHCb experiment is based on complete event readout at 1 MHz. A set of 320 sub-detector readout boards transmit event fragments at total rate of 24.6 MHz at a bandwidth usage of up to 70 GB/s over a commercial switching network based on Gigabit Ethernet to a distributed event building and high-level trigger processing farm with 1470 individual multi-core computer nodes. In the original specifications, the readout was based on a pure push protocol. This paper describes the proposal, implementation, and experience of a non-conventional mixture of a push and a pull protocol, akin to credit-based flow control. An FPGA-based central master module, partly operating at the LHC bunch clock frequency of 40.08 MHz and partly at a double clock speed, is in charge of the entire trigger and readout control from the front-end electronics up to the high-level trigger farm. One FPGA is dedicated to controlling the event fragment packing in the readout boards, the assignment of the farm node destination for each event, and controls the farm load based on an asynchronous pull mechanism from each farm node. This dynamic readout scheme relies on generic event requests and the concept of node credit allowing load control and trigger rate regulation as a function of the global farm load. It also allows the vital task of fast central monitoring and automatic recovery in-flight of failing nodes while maintaining dead-time and event loss at a minimum. This paper demonstrates the strength and suitability of implementing this real-time task for a very large distributed system in an FPGA where no random delays are introduced, and where extreme reliability and accurate event accounting are fundamental requirements. It was in use during the entire commissioning phase of LHCb and has been in faultless operation during the first two years of physics luminosity data taking.

  4. Feasibility and Effectiveness of mHealth for Mobilizing Households for Indoor Residual Spraying to Prevent Malaria: A Case Study in Mali.

    Science.gov (United States)

    Mangam, Keith; Fiekowsky, Elana; Bagayoko, Moussa; Norris, Laura; Belemvire, Allison; Longhany, Rebecca; Fornadel, Christen; George, Kristen

    2016-06-20

    Health approaches for similar IRS mobilization efforts in Mali should be done in a way that combines mHealth tools with more common human-based interventions, rather than as a stand-alone approach, and should be designed with a gender lens in mind. The choice of software used for mass messaging should also be considered to find a local option that is both less expensive and perhaps more attuned to the local context than a U.S.-based software solution. PMID:27353616

  5. A PEG Construction of LDPC Codes Based on the Betweenness Centrality Metric

    Directory of Open Access Journals (Sweden)

    BHURTAH-SEEWOOSUNGKUR, I.

    2016-05-01

    Full Text Available Progressive Edge Growth (PEG constructions are usually based on optimizing the distance metric by using various methods. In this work however, the distance metric is replaced by a different one, namely the betweenness centrality metric, which was shown to enhance routing performance in wireless mesh networks. A new type of PEG construction for Low-Density Parity-Check (LDPC codes is introduced based on the betweenness centrality metric borrowed from social networks terminology given that the bipartite graph describing the LDPC is analogous to a network of nodes. The algorithm is very efficient in filling edges on the bipartite graph by adding its connections in an edge-by-edge manner. The smallest graph size the new code could construct surpasses those obtained from a modified PEG algorithm - the RandPEG algorithm. To the best of the authors' knowledge, this paper produces the best regular LDPC column-weight two graphs. In addition, the technique proves to be competitive in terms of error-correcting performance. When compared to MacKay, PEG and other recent modified-PEG codes, the algorithm gives better performance over high SNR due to its particular edge and local graph properties.

  6. A Site-Specific Index Based on Weathering Forms Visible in Central Oxford, UK

    Directory of Open Access Journals (Sweden)

    Mary J. Thornbush

    2012-11-01

    Full Text Available The authenticity of much of the stone-work along Queen’s Lane in central Oxford, UK presented an opportunity to produce a photographic survey from which a weathering index could be established. This represents a site-specific approach to devising a weathering form. Because it is photo-based, weathering forms are visible for comparison and classification purposes across disciplines. Limestone pertaining to building ashlar and plinths along this roadway, which mainly belong to Queen’s College, St Edmund Hall, New College, and Hertford College, was classified according to this newly introduced weathering index, the size-extent (S-E index, through consideration of type, size, extent, impact, and trigger. This size- (range and extent-based classification system enables for the assessment of weathering forms of various types, including soiling and decay features as well as those potentially expected in the presence of vegetation and animals. Weathering forms of a range of sizes were present, with a slightly greater abundance of small types (mm-cm in the micro- to mesoscale and more discrete types with a low extent. For this location in central Oxford, chemical weathering was found to be the predominant type of soiling and decay.

  7. An application-layer based centralized information access control for VPN

    Institute of Scientific and Technical Information of China (English)

    OUYANG Kai; ZHOU Jing-li; XIA Tao; YU Sheng-sheng

    2006-01-01

    With the rapid development of Virtual Private Network (VPN), many companies and organizations use VPN to implement their private communication. Traditionally, VPN uses security protocols to protect the confidentiality of data, the message integrity and the endpoint authentication. One core technique of VPN is tunneling, by which clients can access the internal servers traversing VPN. However, the tunneling technique also introduces a concealed security hole. It is possible that ifone vicious user can establish tunneling by the VPN server, he can compromise the internal servers behind the VPN server. So this paper presents a novel Application-layer based Centralized Information Access Control (ACIAC) for VPN to solve this problem.To implement an efficient, flexible and multi-decision access control model, we present two key techniques to ACIAC-the centralized management mechanism and the stream-based access control. Firstly, we implement the information center and the constraints/events center for ACIAC. By the two centers, we can provide an abstract access control mechanism, and the material access control can be decided dynamically by the ACIAC's constraint/event mechanism. Then we logically classify the VPN communication traffic into the access stream and the data stream so that we can tightly couple the features of VPN communication with the access control model. We also provide the design of our ACIAC prototype in this paper.

  8. A Combination of Central Pattern Generator-based and Reflex-based Neural Networks for Dynamic, Adaptive, Robust Bipedal Locomotion

    DEFF Research Database (Denmark)

    Di Canio, Giuliano; Larsen, Jørgen Christian; Wörgötter, Florentin;

    2016-01-01

    the interaction of these systems, implementations with reflexbased or central pattern generator (CPG)-based controllers have been tested on bipedal robot systems. In this paper we will combine the two controller types, into a controller that works with both reflex and CPG signals. We use a reflex-based neural......Robotic systems inspired from humans have always been lightening up the curiosity of engineers and scientists. Of many challenges, human locomotion is a very difficult one where a number of different systems needs to interact in order to generate a correct and balanced pattern. To simulate...... network to generate basic walking patterns of a dynamic bipedal walking robot (DACBOT) and then a CPG-based neural network to ensure robust walking behavior...

  9. A Centralized Energy Efficient Distance Based Routing Protocol for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Rohit D. Gawade

    2016-01-01

    Full Text Available Wireless sensor network (WSN typically consists of a large number of low cost wireless sensor nodes which collect and send various messages to a base station (BS. WSN nodes are small battery powered devices having limited energy resources. Replacement of such energy resources is not easy for thousands of nodes as they are inaccessible to users after their deployment. This generates a requirement of energy efficient routing protocol for increasing network lifetime while minimizing energy consumption. Low Energy Adaptive Clustering Hierarchy (LEACH is a widely used classic clustering algorithm in WSNs. In this paper, we propose a Centralized Energy Efficient Distance (CEED based routing protocol to evenly distribute energy dissipation among all sensor nodes. We calculate optimum number of cluster heads based on LEACH’s energy dissipation model. We propose a distributed cluster head selection algorithm based on dissipated energy of a node and its distance to BS. Moreover, we extend our protocol by multihop routing scheme to reduce energy dissipated by nodes located far away from base station. The performance of CEED is compared with other protocols such as LEACH and LEACH with Distance Based Thresholds (LEACH-DT. Simulation results show that CEED is more energy efficient as compared to other protocols. Also it improves the network lifetime and stability period over the other protocols.

  10. Accurate stress analysis on rigid central buckle of long-span suspension bridges based on submodel method

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Runyang Suspension Bridge (RSB) with the main span of 1490 m is the longest bridge in China and the third longest one in the world. In this bridge the rigid central buckle is employed for the first time in the mid-span of the suspension bridge in China. For such a super-long-span bridge, the traditional finite element (FE) modeling technique and stress analysis methods obviously cannot satisfy the needs of conducting accurate stress analysis on the central buckle. In this paper, the submodel method is in- troduced and for the first time used in analyzing the stresses of the central buckle. After an accurate FE submodel of the central buckle was specially established according to the analysis results from the whole FE model, the connection technique between the two-scale FE models was realized and the ac- curate stresses of the central buckle under various vehicle load cases were then conducted based on the submodel method. The calculation results were testified to be accurate and reliable by the field measurements, which show the efficiency and reliability of the submodel method on analyzing the mechanical condition of the central buckle of long-span suspension bridges. Finally, the working be- havior and mechanical characteristics of the central buckle of the RSB under vehicle loads were ana- lyzed based on the calculation and measurement results. The results obtained in this paper can provide theoretic references for analyzing and designing the rigid central buckle in long-span suspension bridges in future.

  11. Successful field trial of attractive toxic sugar bait (ATSB plant-spraying methods against malaria vectors in the Anopheles gambiae complex in Mali, West Africa

    Directory of Open Access Journals (Sweden)

    Doumbia Seydou

    2010-07-01

    Full Text Available Abstract Background Based on highly successful demonstrations in Israel that attractive toxic sugar bait (ATSB methods can decimate local populations of mosquitoes, this study determined the effectiveness of ATSB methods for malaria vector control in the semi-arid Bandiagara District of Mali, West Africa. Methods Control and treatment sites, selected along a road that connects villages, contained man-made ponds that were the primary larval habitats of Anopheles gambiae and Anopheles arabiensis. Guava and honey melons, two local fruits shown to be attractive to An. gambiae s.l., were used to prepare solutions of Attractive Sugar Bait (ASB and ATSB that additionally contained boric acid as an oral insecticide. Both included a color dye marker to facilitate determination of mosquitoes feeding on the solutions. The trial was conducted over a 38-day period, using CDC light traps to monitor mosquito populations. On day 8, ASB solution in the control site and ATSB solution in the treatment site were sprayed using a hand-pump on patches of vegetation. Samples of female mosquitoes were age-graded to determine the impact of ATSB treatment on vector longevity. Results Immediately after spraying ATSB in the treatment site, the relative abundance of female and male An. gambiae s.l. declined about 90% from pre-treatment levels and remained low. In the treatment site, most females remaining after ATSB treatment had not completed a single gonotrophic cycle, and only 6% had completed three or more gonotrophic cycles compared with 37% pre-treatment. In the control site sprayed with ASB (without toxin, the proportion of females completing three or more gonotrophic cycles increased from 28.5% pre-treatment to 47.5% post-treatment. In the control site, detection of dye marker in over half of the females and males provided direct evidence that the mosquitoes were feeding on the sprayed solutions. Conclusion This study in Mali shows that even a single application of

  12. Central FPGA-based Destination and Load Control in the LHCb MHz Event Readout

    CERN Document Server

    Jacobsson, Richard

    2012-01-01

    The readout strategy of the LHCb experiment [1] is based on complete event readout at 1 MHz [2]. Over 300 sub-detector readout boards transmit event fragments at 1 MHz over a commercial 70 Gigabyte/s switching network to a distributed event building and trigger processing farm with 1470 individual multi-core computer nodes [3]. In the original specifications, the readout was based on a pure push protocol. This paper describes the proposal, implementation, and experience of a powerful non-conventional mixture of a push and a pull protocol, akin to credit-based flow control. A high-speed FPGA-based central master module controls the event fragment packing in the readout boards, the assignment of the farm node destination for each event, and controls the farm load based on an asynchronous pull mechanism from each farm node. This dynamic readout scheme relies on generic event requests and the concept of node credit allowing load balancing and trigger rate regulation as a function of the global farm load. It also ...

  13. Surveillance of Food- and Smear-Transmitted Pathogens in European Soldiers with Diarrhea on Deployment in the Tropics: Experience from the European Union Training Mission (EUTM) Mali

    Science.gov (United States)

    Frickmann, Hagen; Warnke, Philipp; Frey, Claudia; Schmidt, Salvatore; Janke, Christian; Erkens, Kay; Schotte, Ulrich; Köller, Thomas; Maaßen, Winfried; Podbielski, Andreas; Binder, Alfred; Hinz, Rebecca; Queyriaux, Benjamin; Wiemer, Dorothea; Schwarz, Norbert Georg; Hagen, Ralf Matthias

    2015-01-01

    Introduction. Since 2013, European soldiers have been deployed on the European Union Training Mission (EUTM) in Mali. From the beginning, diarrhea has been among the most “urgent” concerns. Diarrhea surveillance based on deployable real-time PCR equipment was conducted between December 2013 and August 2014. Material and Methods. In total, 53 stool samples were obtained from 51 soldiers with acute diarrhea. Multiplex PCR panels comprised enteroinvasive bacteria, diarrhea-associated Escherichia coli (EPEC, ETEC, EAEC, and EIEC), enteropathogenic viruses, and protozoa. Noroviruses were characterized by sequencing. Cultural screening for Enterobacteriaceae with extended-spectrum beta-lactamases (ESBL) with subsequent repetitive sequence-based PCR (rep-PCR) typing was performed. Clinical information was assessed. Results. Positive PCR results for diarrhea-associated pathogens were detected in 43/53 samples, comprising EPEC (n = 21), ETEC (n = 19), EAEC (n = 15), Norovirus (n = 10), Shigella spp./EIEC (n = 6), Cryptosporidium parvum (n = 3), Giardia duodenalis (n = 2), Salmonella spp. (n = 1), Astrovirus (n = 1), Rotavirus (n = 1), and Sapovirus (n = 1). ESBL-positive Enterobacteriaceae were grown from 13 out of 48 samples. Simultaneous infections with several enteropathogenic agents were observed in 23 instances. Symptoms were mild to moderate. There were hints of autochthonous transmission. Conclusions. Multiplex real-time PCR proved to be suitable for diarrhea surveillance on deployment. Etiological attribution is challenging in cases of detection of multiple pathogens. PMID:26525953

  14. Surveillance of Food- and Smear-Transmitted Pathogens in European Soldiers with Diarrhea on Deployment in the Tropics: Experience from the European Union Training Mission (EUTM Mali

    Directory of Open Access Journals (Sweden)

    Hagen Frickmann

    2015-01-01

    Full Text Available Introduction. Since 2013, European soldiers have been deployed on the European Union Training Mission (EUTM in Mali. From the beginning, diarrhea has been among the most “urgent” concerns. Diarrhea surveillance based on deployable real-time PCR equipment was conducted between December 2013 and August 2014. Material and Methods. In total, 53 stool samples were obtained from 51 soldiers with acute diarrhea. Multiplex PCR panels comprised enteroinvasive bacteria, diarrhea-associated Escherichia coli (EPEC, ETEC, EAEC, and EIEC, enteropathogenic viruses, and protozoa. Noroviruses were characterized by sequencing. Cultural screening for Enterobacteriaceae with extended-spectrum beta-lactamases (ESBL with subsequent repetitive sequence-based PCR (rep-PCR typing was performed. Clinical information was assessed. Results. Positive PCR results for diarrhea-associated pathogens were detected in 43/53 samples, comprising EPEC (n=21, ETEC (n=19, EAEC (n=15, Norovirus (n=10, Shigella spp./EIEC (n=6, Cryptosporidium parvum (n=3, Giardia duodenalis (n=2, Salmonella spp. (n=1, Astrovirus (n=1, Rotavirus (n=1, and Sapovirus (n=1. ESBL-positive Enterobacteriaceae were grown from 13 out of 48 samples. Simultaneous infections with several enteropathogenic agents were observed in 23 instances. Symptoms were mild to moderate. There were hints of autochthonous transmission. Conclusions. Multiplex real-time PCR proved to be suitable for diarrhea surveillance on deployment. Etiological attribution is challenging in cases of detection of multiple pathogens.

  15. Ear Nose and throat diseases in paediatric patients at a secondary hospital in Mali

    Directory of Open Access Journals (Sweden)

    Sacko Baba Hamidou

    2015-12-01

    Full Text Available The Nose throat and Ear diseases of the child taking into account specificities anatomo-clinical require special attention to adequate support. This study was designed to highlight the different aspects of the ENT disorders of the child in our unit. We identified 819 children aged 0-15 years with ENT diseases between January and December 2014 in the ENT unit of the Health reference center of district IV Bamako. There was a predominance of the male 464 (56.65%. Conditions were especially concerned the age group from 0 to 2 years 364 (44.44%. The most common ENT diseases seen where otitis media 33.21%, followed by nasopharyngitis 14.16% and impacted wax 10.13%. The main ENT emergencies were 96 patients and focused mainly on the foreign bodies 35.41% and trauma 28.12%. This study allowed us to determine the main ENT disorders of the child in our unit and propose relevant recommendations for a healthy promotion of Paediatric Otolaryngology in Mali.

  16. Pesticides Occurrence in an Alfisol of Sudano-Sahelian Agricultural Watershed (Korokoro, Mali

    Directory of Open Access Journals (Sweden)

    Amadou Maiga

    2014-08-01

    Full Text Available Soil contamination by pesticides (organochlorine, organophosphates and pyrethroids has been studied in the agricultural watershed (60.6 km2 of Korokoro in Mali. Farmers of this watershed produce cotton and cereals (sorghum, maize, millet. Soil samples (0-20 cm of an alfisol used for cotton cropping were collected at the end of the cropping seasons 2010 and 2011. Samples were analyzed by gas chromatography and mass spectrometer for quantifying the main pesticides (profenofos, acetamiprid, atrazine and cypermethrin frequently used in the watershed and others organochlorine pesticides (DDT, endosulfan and HCH that could be still detected. The results showed that soils were contaminated by DDT and its metabolites (0.1 to 3.5 µg.kg-1 due to past agricultural uses for African migratory locust control while those of endosulfan sulfate (detection limit to 4.2 µg.kg-1 and cypermethrin (2.5 to 6.2 µg.kg-1 were due to their actual application on cotton. According to mass balances calculation cypermethrin residues are stocked in the soil compartment of the watershed after its application on cotton. This accumulation was evaluated at 13 ± 0.4% of applied quantities.

  17. Operationalizing Civilian Protection in Mali: The Case for a Civilian Casualty Tracking, Analysis, and Response Cell

    Directory of Open Access Journals (Sweden)

    Marla B. Keenan

    2013-06-01

    Full Text Available This practice note details an emerging best practice of civilian harm mitigation in armed conflict: namely, the creation of civilian casualty tracking, analysis and response processes by a warring party or peace operation force. It asserts that in Iraq, Afghanistan and soon Somalia, these processes to better understand civilian harm and address consequences have positively shaped mission tactics, training, and overall operations. In both Iraq and Afghanistan, tracking and analysis has lead to a marked decrease in civilian casualties and facilitated the making of amends for any civilian losses. The paper argues that for warring parties to achieve their mission—particularly one with a protection of civilians mandate as with the United Nations Multidimensional Integrated Stabilization Mission in Mali (MINUSMA—they must fully understand the impact of their actions on the civilian population, positive or negative. For this reason, a Civilian Casualty Tracking, Analysis, and Response Cell should be created for MINUSMA to improve its ability mitigate risk to civilians as required by its Security Council mandate.

  18. National Report of Mali on Implementation of the IAEA Code of Conduct

    International Nuclear Information System (INIS)

    The Republic of Mali is member of the International Atomic Energy Agency since 1961. of Since the creation of the IAEA. The technical cooperation with the Agency started in the years 1975. Through that cooperation, many pacific uses of nuclear techniques have been introduced, then developed at different levels in many socio- economic domains as medicine, agriculture, research, and so on. That development of nuclear techniques use has occurred without legislation at all or in some limited cases with part of the legislation of the colonizing country), in a precise field (like radiography in medicine). Later the need of regulatory infrastructure implementation started. That implementation has followed several ways in the different African countries. Also, it started earlier in countries which had advanced activities in nuclear techniques and very later in others. Most if not all of these infrastructures (say regulatory board) were created by the greatest users of the nuclear techniques, the Ministry of Health in most cases or Energy Commission for Countries having a research reactor. After the years 90, the Agency has developed new vision in the implementation of Regulatory Authorities. The new innovation was: - Development of Regulatory Authority with independent statute ( decisions and finance) ; - Assuming post graduate training in developing countries to come other the lack of human resources. That new strategy of the IAEA has facilitated the apparition and development of several new regulatory authorities. We are going to develop here the progress done by one of these new regulatory authorities, through five years being. (author)

  19. Impact of Climate Change on Groundwater Resources in the Klela Basin, Southern Mali

    Directory of Open Access Journals (Sweden)

    Adama Toure

    2016-05-01

    Full Text Available Investigations of groundwater resources in order to understand aquifer system behavior are vital to the inhabitants of the Klela Basin, Mali, because groundwater is the only permanent water resource and is used for drinking water and irrigation. Due to climate change, this vital resource is being threatened. Therefore, MODFLOW was applied in this study to simulate groundwater dynamics. The aim of this study was to evaluate the impact of climate change on groundwater resources in the Klela basin using the RCP4.5 (Representative Concentration Scenario 4.5 W/m2 climate scenario. Climatological, geological, hydrogeological, hydraulic and demographic data were collected and used as model input data. Groundwater recharge was estimated to be approximately 165.3 mm/year using the EARTH (Extended model for Aquifer Recharge and soil moisture Transport through the unsaturated Hardrock model. Recharge was then used as groundwater model input. The sandstone aquifer in the study area was simulated in steady and transient conditions. The results showed that hydraulic conductivity values varied from 1.1 to 13.9 m/day. The model was used for scenario quantification after model calibration and verification using three different piezometer data sets. The results of the simulated MODFLOW model showed a decrease in groundwater levels over time.

  20. Rural children's attitudes to people with HIV/AIDS in Mali: the causes of stigma.

    Science.gov (United States)

    Castle, Sarah

    2004-01-01

    Qualitative research among young people and other community members in rural Mali elicited knowledge and attitudes with regard to HIV/AIDS. Findings indicated that rumours concerning methods of infection are likely to increase the stigmatization of those with the disease. The most frequently stated mode of transmission involved urinating in a place where someone with AIDS had already urinated. Shared clothes, food and water were seen as sources of infection. Both children and teachers recommended that people with AIDS be isolated. Even talking to them would lead to a risk of infection. Discriminatory views were likely to have been reinforced by parents and community elders who possessed the same misinformation. The notion that AIDS results from sexual encounters between young women and dogs belonging to white people in Côte d'Ivoire was also widespread. These discourses may reflect perceived xenophobia and risk to migrants associated with current tensions between the two countries, together with misgivings about Western sexual liberalism. A holistic educational programme is proposed to address not simply HIV/AIDS, but the social context in which infection occurs, with view to combating stigma and discrimination associated with not just HIV but also with migration in this setting. PMID:21972829

  1. Ethnopharmacological survey of six medicinal plants from Mali, West-Africa

    Directory of Open Access Journals (Sweden)

    Bah Sekou

    2008-12-01

    Full Text Available Abstract An ethnopharmacological survey was carried out to collect information about the use of six medicinal plants in the regions around Siby and Dioila, Mali. The plants investigated were Biopyhtum petersianum, Cola cordifolia, Combretum molle, Opilia celtidifolia, Parkia biglobosa and Ximenia americana. More than 60 medical indications were reported for the use of these plants in traditional medicine. The most frequently reported ailments were malaria (25.6%, different types of pain (14.0% and dermatitis (7.4%. The main forms for preparation were decoction (58.1% and powdered plant material (28.4%. The most frequent used plant parts were leaves (37.7% and stem bark (18.6%. The healers' consensus for the main indications is fairly high for the four plants B. petersianum, C. cordifolia, C. molle and O. celtidifolia, and this supports the traditional use of these plants. However for P. biglobosa and X. americana the healers' consensus is less consistent and it is more difficult to draw conclusions about the most important traditional use of these two plants.

  2. Ethnopharmacological survey of six medicinal plants from Mali, West-Africa.

    Science.gov (United States)

    Grønhaug, Tom Erik; Glaeserud, Silje; Skogsrud, Mona; Ballo, Ngolo; Bah, Sekou; Diallo, Drissa; Paulsen, Berit Smestad

    2008-12-27

    An ethnopharmacological survey was carried out to collect information about the use of six medicinal plants in the regions around Siby and Dioila, Mali. The plants investigated were Biopyhtum petersianum, Cola cordifolia, Combretum molle, Opilia celtidifolia, Parkia biglobosa and Ximenia americana. More than 60 medical indications were reported for the use of these plants in traditional medicine. The most frequently reported ailments were malaria (25.6%), different types of pain (14.0%) and dermatitis (7.4%). The main forms for preparation were decoction (58.1%) and powdered plant material (28.4%). The most frequent used plant parts were leaves (37.7%) and stem bark (18.6%). The healers' consensus for the main indications is fairly high for the four plants B. petersianum, C. cordifolia, C. molle and O. celtidifolia, and this supports the traditional use of these plants. However for P. biglobosa and X. americana the healers' consensus is less consistent and it is more difficult to draw conclusions about the most important traditional use of these two plants.

  3. Vulnerability and the Role of Education in Environmentally Induced Migration in Mali and Senegal

    Directory of Open Access Journals (Sweden)

    Victoria van der Land

    2013-12-01

    Full Text Available In the West African Sahel, the majority of the population depends on subsistence farming and livestock breeding and is thus particularly vulnerable to climatic changes. One possible response to natural hazards is migration. Recent research suggests that environmentally induced mobility is closely linked to the social vulnerability and adaptive capacity of individuals and groups. However, only little attention has been paid thus far to the role of formal education in this context. Our objective was to fill this gap by examining the role of formal education in environmentally induced migration as one characteristic of social vulnerability to environmental change. Our analysis focuses on two regions in the West African Sahel, Bandiagara in Mali and Linguère in Senegal, that are presumed to be particularly affected by climate change and environmental degradation. Our results reveal that formal education plays an important role in reducing vulnerability to environmental stress because people with a higher level of education are usually less dependent on environmentally sensitive economic activities such as farming. Moreover, an agricultural economic activity can be an obstacle to a high level of formal education. We found no significant effect of people's education on the migration experience as such. However, motives for migration differ considerably depending on the amount of education received, suggesting that migration constitutes a livelihood strategy, particularly for the lower educated.

  4. Branch-based centralized data collection for smart grids using wireless sensor networks.

    Science.gov (United States)

    Kim, Kwangsoo; Jin, Seong-il

    2015-05-21

    A smart grid is one of the most important applications in smart cities. In a smart grid, a smart meter acts as a sensor node in a sensor network, and a central device collects power usage from every smart meter. This paper focuses on a centralized data collection problem of how to collect every power usage from every meter without collisions in an environment in which the time synchronization among smart meters is not guaranteed. To solve the problem, we divide a tree that a sensor network constructs into several branches. A conflict-free query schedule is generated based on the branches. Each power usage is collected according to the schedule. The proposed method has important features: shortening query processing time and avoiding collisions between a query and query responses. We evaluate this method using the ns-2 simulator. The experimental results show that this method can achieve both collision avoidance and fast query processing at the same time. The success rate of data collection at a sink node executing this method is 100%. Its running time is about 35 percent faster than that of the round-robin method, and its memory size is reduced to about 10% of that of the depth-first search method.

  5. Branch-based centralized data collection for smart grids using wireless sensor networks.

    Science.gov (United States)

    Kim, Kwangsoo; Jin, Seong-il

    2015-01-01

    A smart grid is one of the most important applications in smart cities. In a smart grid, a smart meter acts as a sensor node in a sensor network, and a central device collects power usage from every smart meter. This paper focuses on a centralized data collection problem of how to collect every power usage from every meter without collisions in an environment in which the time synchronization among smart meters is not guaranteed. To solve the problem, we divide a tree that a sensor network constructs into several branches. A conflict-free query schedule is generated based on the branches. Each power usage is collected according to the schedule. The proposed method has important features: shortening query processing time and avoiding collisions between a query and query responses. We evaluate this method using the ns-2 simulator. The experimental results show that this method can achieve both collision avoidance and fast query processing at the same time. The success rate of data collection at a sink node executing this method is 100%. Its running time is about 35 percent faster than that of the round-robin method, and its memory size is reduced to about 10% of that of the depth-first search method. PMID:26007734

  6. Branch-Based Centralized Data Collection for Smart Grids Using Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Kwangsoo Kim

    2015-05-01

    Full Text Available A smart grid is one of the most important applications in smart cities. In a smart grid, a smart meter acts as a sensor node in a sensor network, and a central device collects power usage from every smart meter. This paper focuses on a centralized data collection problem of how to collect every power usage from every meter without collisions in an environment in which the time synchronization among smart meters is not guaranteed. To solve the problem, we divide a tree that a sensor network constructs into several branches. A conflict-free query schedule is generated based on the branches. Each power usage is collected according to the schedule. The proposed method has important features: shortening query processing time and avoiding collisions between a query and query responses. We evaluate this method using the ns-2 simulator. The experimental results show that this method can achieve both collision avoidance and fast query processing at the same time. The success rate of data collection at a sink node executing this method is 100%. Its running time is about 35 percent faster than that of the round-robin method, and its memory size is reduced to about 10% of that of the depth-first search method.

  7. Separating temporal and topological effects in walk-based network centrality

    Science.gov (United States)

    Colman, Ewan R.; Charlton, Nathaniel

    2016-07-01

    The recently introduced concept of dynamic communicability is a valuable tool for ranking the importance of nodes in a temporal network. Two metrics, broadcast score and receive score, were introduced to measure the centrality of a node with respect to a model of contagion based on time-respecting walks. This article examines the temporal and structural factors influencing these metrics by considering a versatile stochastic temporal network model. We analytically derive formulas to accurately predict the expectation of the broadcast and receive scores when one or more columns in a temporal edge-list are shuffled. These methods are then applied to two publicly available data sets and we quantify how much the centrality of each individual depends on structural or temporal influences. From our analysis, we highlight two practical contributions: a way to control for temporal variation when computing dynamic communicability and the conclusion that the broadcast and receive scores can, under a range of circumstances, be replaced by the row and column sums of the matrix exponential of a weighted adjacency matrix given by the data.

  8. Quantitative study on pollen-based reconstructions of vegetation history from central Canada

    Institute of Scientific and Technical Information of China (English)

    YU Ge; HART Catherina; VETTER Mary; SAUCHYN David

    2008-01-01

    Based on high-resolution pollen records from lake cores in central Canada, the present study instructed pollen taxa assignations in ecosystem groups and modern analogue technique, reported major results of quantitative reconstructions of vegetation history during the last 1000 years, and discussed the validation of simulated vegetation. The results showed that in central America (115°-95°W,40°-60°N), best analogue of the modern vegetation is 81% for boreal forest, 72% for parkland, and 94% for grassland-parkland, which are consistent with vegetation distributions of the North American Ecosystem Ⅱ. Simulations of the past vegetation from the sedimentary pollen showed climate changes during the past 1000 years: it was warm and dry in the Medieval Warm period, cold and wet in the earlier period and cold and dry in the later period of the Little Ice Age. It became obviously increasing warm and drought in the 20th century. The present studies would provide us scientific basis to understand vegetation and climate changes during the last 1000 years in a characteristic region and in 10-100 year time scales.

  9. Quantitative study on pollen-based reconstructions of vegetation history from central Canada

    Institute of Scientific and Technical Information of China (English)

    HART; Catherina; VETTER; Mary; SAUCHYN; David

    2008-01-01

    Based on high-resolution pollen records from lake cores in central Canada, the present study instructed pollen taxa assignations in ecosystem groups and modern analogue technique, reported major results of quantitative reconstructions of vegetation history during the last 1000 years, and discussed the validation of simulated vegetation. The results showed that in central America (115°-95°W, 40°-60°N), best analogue of the modern vegetation is 81% for boreal forest, 72% for parkland, and 94% for grassland-parkland, which are consistent with vegetation distributions of the North American Ecosystem II. Simulations of the past vegetation from the sedimentary pollen showed climate changes during the past 1000 years: it was warm and dry in the Medieval Warm period, cold and wet in the earlier period and cold and dry in the later period of the Little Ice Age. It became obviously increasing warm and drought in the 20th century. The present studies would provide us scientific basis to understand vegetation and climate changes during the last 1000 years in a characteristic region and in 10-100 year time scales.

  10. Efficient crop type mapping based on remote sensing in the Central Valley, California

    Science.gov (United States)

    Zhong, Liheng

    Most agricultural systems in California's Central Valley are purposely flexible and intentionally designed to meet the demands of dynamic markets. Agricultural land use is also impacted by climate change and urban development. As a result, crops change annually and semiannually, which makes estimating agricultural water use difficult, especially given the existing method by which agricultural land use is identified and mapped. A minor portion of agricultural land is surveyed annually for land-use type, and every 5 to 8 years the entire valley is completely evaluated. So far no effort has been made to effectively and efficiently identify specific crop types on an annual basis in this area. The potential of satellite imagery to map agricultural land cover and estimate water usage in the Central Valley is explored. Efforts are made to minimize the cost and reduce the time of production during the mapping process. The land use change analysis shows that a remote sensing based mapping method is the only means to map the frequent change of major crop types. The traditional maximum likelihood classification approach is first utilized to map crop types to test the classification capacity of existing algorithms. High accuracy is achieved with sufficient ground truth data for training, and crop maps of moderate quality can be timely produced to facilitate a near-real-time water use estimate. However, the large set of ground truth data required by this method results in high costs in data collection. It is difficult to reduce the cost because a trained classification algorithm is not transferable between different years or different regions. A phenology based classification (PBC) approach is developed which extracts phenological metrics from annual vegetation index profiles and identifies crop types based on these metrics using decision trees. According to the comparison with traditional maximum likelihood classification, this phenology-based approach shows great advantages

  11. Fractal Systems of Central Places Based on Intermittency of Space-filling

    CERN Document Server

    Chen, Yanguang

    2011-01-01

    The central place models are fundamentally important in theoretical geography and city planning theory. The texture and structure of central place networks have been demonstrated to be self-similar in both theoretical and empirical studies. However, the underlying rationale of central place fractals in the real world has not yet been revealed so far. This paper is devoted to illustrating the mechanisms by which the fractal patterns can be generated from central place systems. The structural dimension of the traditional central place models is d=2 indicating no intermittency in the spatial distribution of human settlements. This dimension value is inconsistent with empirical observations. Substituting the complete space filling with the incomplete space filling, we can obtain central place models with fractional dimension Dcentral place models are converted into fractal central place models. If we further integrate the chance factors into the i...

  12. LexRank: Graph-based Lexical Centrality as Salience in Text Summarization

    CERN Document Server

    Erkan, G; 10.1613/jair.1523

    2011-01-01

    We introduce a stochastic graph-based method for computing relative importance of textual units for Natural Language Processing. We test the technique on the problem of Text Summarization (TS). Extractive TS relies on the concept of sentence salience to identify the most important sentences in a document or set of documents. Salience is typically defined in terms of the presence of particular important words or in terms of similarity to a centroid pseudo-sentence. We consider a new approach, LexRank, for computing sentence importance based on the concept of eigenvector centrality in a graph representation of sentences. In this model, a connectivity matrix based on intra-sentence cosine similarity is used as the adjacency matrix of the graph representation of sentences. Our system, based on LexRank ranked in first place in more than one task in the recent DUC 2004 evaluation. In this paper we present a detailed analysis of our approach and apply it to a larger data set including data from earlier DUC evaluatio...

  13. Distortion-Invariant Binary Image Recognition Based on Central Projection Correlation

    Institute of Scientific and Technical Information of China (English)

    WU Yaming; XIAO Yanping; SUN Fanghong; FANG Nian

    2001-01-01

    A method of central projection correlation which is invariant to distortion of shift, scale and rotation of the binary target image is proposed. A 2-D binary image is transformed into an 1-D central projection referring to the centroid of the binary image. The distortion-invariant central projection correlation is successfully performed by computer simulations and its optical implementation is presented.

  14. SOTER-based soil parameter estimates for Central and Eastern Europe (ver. 2.0)

    NARCIS (Netherlands)

    Batjes, N.H.

    2005-01-01

    This harmonized set of soil parameter estimates for Central and Eastern Europe has been derived from a revised version of the 1:2.5M Soil and Terrain (SOTER) Database for Central and Eastern Europe (SOVEUR ver. 1.1) and the ISRIC-WISE soil profile database. The land surface of Central and Eastern Eu

  15. Situational Lightning Climatologies for Central Florida: Phase IV: Central Florida Flow Regime Based Climatologies of Lightning Probabilities

    Science.gov (United States)

    Bauman, William H., III

    2009-01-01

    The threat of lightning is a daily concern during the warm season in Florida. Research has revealed distinct spatial and temporal distributions of lightning occurrence that are strongly influenced by large-scale atmospheric flow regimes. Previously, the Applied Meteorology Unit (AMU) calculated the gridded lightning climatologies based on seven flow regimes over Florida for 1-, 3- and 6-hr intervals in 5-, 10-, 20-, and 30-NM diameter range rings around the Shuttle Landing Facility (SLF) and eight other airfields in the National Weather Service in Melbourne (NWS MLB) county warning area (CWA). In this update to the work, the AMU recalculated the lightning climatologies for using individual lightning strike data to improve the accuracy of the climatologies. The AMU included all data regardless of flow regime as one of the stratifications, added monthly stratifications, added three years of data to the period of record and used modified flow regimes based work from the AMU's Objective Lightning Probability Forecast Tool, Phase II. The AMU made changes so the 5- and 10-NM radius range rings are consistent with the aviation forecast requirements at NWS MLB, while the 20- and 30-NM radius range rings at the SLF assist the Spaceflight Meteorology Group in making forecasts for weather Flight Rule violations during Shuttle landings. The AMU also updated the graphical user interface with the new data.

  16. Phylogenetic analysis of Persian Gazella, Gazella subgutturosa (Artiodactyla: Bovidae based on cytochrome b in central Iran

    Directory of Open Access Journals (Sweden)

    Davoud Fadakar

    2013-12-01

    Full Text Available Persian gazelle, Gazella subgutturosa, exists throughout arid and semiarid regions of Iran and has a key role in these frail ecosystems. Habitat degradation and population decline has placed it on the list of vulnerable species in 2008. The phylogenetic relationships of three Persian gazelle populations in the central part of Iran (i.e. Ghamishlou National Park and Wildlife Refuge, Mouteh Wildlife Refuge in Isfahan province and Kalmand-Bahadoran Protected Area in Yazd province were investigated using parts and short fragments of mitochondrial cytochrome b gene (425 base pairs. A maximum likelihood phylogenetic tree separated the populations of Yazd and Isfahan provinces, but populations within the Isfahan province shared the same clade. All populations were classified as Persian gazelle. The studied populations are facing threats because of road construction, industrial development and urbanization. Accordingly urgent conservation plans are needed to preserve their genetic diversity and prevent them from falling into extinction.

  17. Village-based primary health care in the Central Highlands of Vietnam.

    Science.gov (United States)

    Barrett, B; Ladinsky, J; Volk, N

    2001-02-01

    This paper describes the first year of an ongoing village health care and economic development project in the Krong Buk district of Dak Lak province in Vietnam's Central Highlands. The project serves 21 villages with a total population of just over 15,000. Most belong to ethnic minority groups. Physicians from the province capital of Boun Me Thuot were trained by a multi-disciplinary team of American health care workers to be trainers and supervisors of 21 village health care workers (VHWs). Two months later, a VHW from each village was trained in primary and preventive health care by the physician-supervisors. Since this initial training, each VHW has been provided with materials, medicines and monthly supervision by the physician-supervisors. The health care component has been complemented by an economic development project based on a system of small loans. Data from the first year of monthly reports and from a baseline survey are presented in this paper.

  18. Satellite-based detection of volcanic sulphur dioxide from recent eruptions in Central and South America

    Directory of Open Access Journals (Sweden)

    D. Loyola

    2008-01-01

    Full Text Available Volcanic eruptions can emit large amounts of rock fragments and fine particles (ash into the atmosphere, as well as several gases, including sulphur dioxide (SO2. These ejecta and emissions are a major natural hazard, not only to the local population, but also to the infrastructure in the vicinity of volcanoes and to aviation. Here, we describe a methodology to retrieve quantitative information about volcanic SO2 plumes from satellite-borne measurements in the UV/Visible spectral range. The combination of a satellite-based SO2 detection scheme and a state-of-the-art 3D trajectory model enables us to confirm the volcanic origin of trace gas signals and to estimate the plume height and the effective emission height. This is demonstrated by case-studies for four selected volcanic eruptions in South and Central America, using the GOME, SCIAMACHY and GOME-2 instruments.

  19. Measuring long-term impact based on network centrality: unraveling cinematic citations.

    Directory of Open Access Journals (Sweden)

    Andreas Spitz

    Full Text Available Traditional measures of success for film, such as box-office revenue and critical acclaim, lack the ability to quantify long-lasting impact and depend on factors that are largely external to the craft itself. With the growing number of films that are being created and large-scale data becoming available through crowd-sourced online platforms, an endogenous measure of success that is not reliant on manual appraisal is of increasing importance. In this article we propose such a ranking method based on a combination of centrality indices. We apply the method to a network that contains several types of citations between more than 40,000 international feature films. From this network we derive a list of milestone films, which can be considered to constitute the foundations of cinema. In a comparison to various existing lists of 'greatest' films, such as personal favourite lists, voting lists, lists of individual experts, and lists deduced from expert polls, the selection of milestone films is more diverse in terms of genres, actors, and main creators. Our results shed light on the potential of a systematic quantitative investigation based on cinematic influences in identifying the most inspiring creations in world cinema. In a broader perspective, we introduce a novel research question to large-scale citation analysis, one of the most intriguing topics that have been at the forefront of scientific enquiries for the past fifty years and have led to the development of various network analytic methods. In doing so, we transfer widely studied approaches from citation analysis to the the newly emerging field of quantification efforts in the arts. The specific contribution of this paper consists in modelling the multidimensional cinematic references as a growing multiplex network and in developing a methodology for the identification of central films in this network.

  20. Measuring long-term impact based on network centrality: unraveling cinematic citations.

    Science.gov (United States)

    Spitz, Andreas; Horvát, Emőke-Ágnes

    2014-01-01

    Traditional measures of success for film, such as box-office revenue and critical acclaim, lack the ability to quantify long-lasting impact and depend on factors that are largely external to the craft itself. With the growing number of films that are being created and large-scale data becoming available through crowd-sourced online platforms, an endogenous measure of success that is not reliant on manual appraisal is of increasing importance. In this article we propose such a ranking method based on a combination of centrality indices. We apply the method to a network that contains several types of citations between more than 40,000 international feature films. From this network we derive a list of milestone films, which can be considered to constitute the foundations of cinema. In a comparison to various existing lists of 'greatest' films, such as personal favourite lists, voting lists, lists of individual experts, and lists deduced from expert polls, the selection of milestone films is more diverse in terms of genres, actors, and main creators. Our results shed light on the potential of a systematic quantitative investigation based on cinematic influences in identifying the most inspiring creations in world cinema. In a broader perspective, we introduce a novel research question to large-scale citation analysis, one of the most intriguing topics that have been at the forefront of scientific enquiries for the past fifty years and have led to the development of various network analytic methods. In doing so, we transfer widely studied approaches from citation analysis to the the newly emerging field of quantification efforts in the arts. The specific contribution of this paper consists in modelling the multidimensional cinematic references as a growing multiplex network and in developing a methodology for the identification of central films in this network.

  1. Measuring long-term impact based on network centrality: unraveling cinematic citations.

    Science.gov (United States)

    Spitz, Andreas; Horvát, Emőke-Ágnes

    2014-01-01

    Traditional measures of success for film, such as box-office revenue and critical acclaim, lack the ability to quantify long-lasting impact and depend on factors that are largely external to the craft itself. With the growing number of films that are being created and large-scale data becoming available through crowd-sourced online platforms, an endogenous measure of success that is not reliant on manual appraisal is of increasing importance. In this article we propose such a ranking method based on a combination of centrality indices. We apply the method to a network that contains several types of citations between more than 40,000 international feature films. From this network we derive a list of milestone films, which can be considered to constitute the foundations of cinema. In a comparison to various existing lists of 'greatest' films, such as personal favourite lists, voting lists, lists of individual experts, and lists deduced from expert polls, the selection of milestone films is more diverse in terms of genres, actors, and main creators. Our results shed light on the potential of a systematic quantitative investigation based on cinematic influences in identifying the most inspiring creations in world cinema. In a broader perspective, we introduce a novel research question to large-scale citation analysis, one of the most intriguing topics that have been at the forefront of scientific enquiries for the past fifty years and have led to the development of various network analytic methods. In doing so, we transfer widely studied approaches from citation analysis to the the newly emerging field of quantification efforts in the arts. The specific contribution of this paper consists in modelling the multidimensional cinematic references as a growing multiplex network and in developing a methodology for the identification of central films in this network. PMID:25295877

  2. Results-Based Financing in Mozambique’s Central Medical Store: A Review After 1 Year

    Science.gov (United States)

    Spisak, Cary; Morgan, Lindsay; Eichler, Rena; Rosen, James; Serumaga, Brian; Wang, Angela

    2016-01-01

    ABSTRACT Background: Public health commodity supply chains are typically weak in low-income countries, partly because they have many disparate yet interdependent functions and components. Approaches to strengthening supply chains in such settings have often fallen short—they address technical weaknesses, but not the incentives that motivate staff to perform better. Methods: We reviewed the first year of a results-based financing (RBF) program in Mozambique, which began in January 2013. The program aimed to improve the performance of the central medical store—Central de Medicamentos e Artigos Medicos (CMAM)—by realigning incentives. We completed in-depth interviews and focus group discussions with 33 key informants, including representatives from CMAM and donor agencies, and collected quantitative data on performance measures and use of funds. Implementation: The RBF agreement linked CMAM performance payments to quarterly results on 5 performance indicators related to supply planning, distribution planning, and warehouse management. RBF is predicated on the theory that a combination of carrot and stick—i.e., shared financial incentives, plus increased accountability for results—will spur changes in behavior. Important design elements: (1) indicators were measured against quarterly targets, and payments were made only for indicators that met those targets; (2) targets were set based on documented performance, at levels that could be reasonably attained, yet pushed for improvement; (3) payment was shared with and dependent on all staff, encouraging teamwork and collaboration; (4) results were validated by verifiable data sources; and (5) CMAM had discretion over how to use the funds. Findings: We found that CMAM’s performance continually improved over baseline and that CMAM achieved many of its performance targets, for example, timely submission of quarterly supply and distribution planning reports. Warehouse indicators, such as inventory management and

  3. Evaluation of an antibody-detection ELISA using pre-coated plates in the diagnosis of Trypanosoma congolense and T. vivax infections in cattle in Mali

    International Nuclear Information System (INIS)

    Under the Coordinated Research Programme ''Use of immunoassay for improved diagnosis of trypanosomosis and monitoring trypanosomosis control programmes'', a new ELISA test has been validated. The test was designed for trypanosome specific antibody detection. The purpose of the work was to study the main parameters of the test (sensitivity and specificity) using reference sera provided by IAEA and field sera collected in Mali. The field sera were collected in different ecological zones and included sera from trypanosomosis endemic areas as well as sera from tsetse free areas. The test was performed according to the protocol proposed by IAEA. The results have shown a poor stability of the reference sera for both T. congolense and T. vivax. By using de-ionized water, we got better OD's for T. vivax C++ reference serum, while the T. congolense C++ had to be replaced by a locally produced reference serum. Under the above conditions, the T. congolense system gave quite encouraging results (sensitivity: 100%; specificity: 87.5-95%). This system was able to differentiate quite well animals from tsetse infected areas from those originating from tsetse free areas and could therefore be used in epidemiological surveys. The T. vivax system showed a good sensitivity (100%), but a poor specificity (37.5-57.5%). The T. vivax system could be improved by establishing a cut-off point based on local negative populations. (author)

  4. Genetic Diversity of Porang Populations (Amorphophallus Muelleri Blume) In Central Java and West Java Based on LEAFY Second Intron Marker

    OpenAIRE

    Isna Arofatun Nikmah; Rodiyati Azrianingsih; Didik Wahyudi

    2016-01-01

    Porang (Amorphophallus muelleri Blume) is dispersed and grew well in Java island. This research aimed to determine the genetic diversity of porang populations in Central Java and West Java based on LEAFY second intron (nuclear genome encoding flower development). DNA samples of porang were from previous study, which were obtained from Central Java (Pamedaran, Grobogan, Wonogiri, Karangtengah) and West Java (Cisompet) as in-group. Amorphophallus variabilis from Pamedaran Brebes, Amorphophallus...

  5. Risk and agro-pastoral decision-making and natural resource management in Fulbe Society, Central Mali

    NARCIS (Netherlands)

    Dijk, van J.W.M.

    1997-01-01

    Risk and uncertainty dominate life in the semiarid tropics where most of the world's pastoralists live. Scientific approaches to risk in semiarid zones have been dominated by agroecology and agroeconomics. Within these paradigms risk is treated as a stochastic occurrence, and decisionmaking strategi

  6. Estimating gene flow between refuges and crops: a case study of the biological control of Eriosoma lanigerum by Aphelinus mali in apple orchards.

    Directory of Open Access Journals (Sweden)

    Blas Lavandero

    Full Text Available Parasitoid disturbance populations in agroecosystems can be maintained through the provision of habitat refuges with host resources. However, specialized herbivores that feed on different host plants have been shown to form host-specialized races. Parasitoids may subsequently specialize on these herbivore host races and therefore prefer parasitizing insects from the refuge, avoiding foraging on the crop. Evidence is therefore required that parasitoids are able to move between the refuge and the crop and that the refuge is a source of parasitoids, without being an important source of herbivore pests. A North-South transect trough the Chilean Central Valley was sampled, including apple orchards and surrounding Pyracantha coccinea (M. Roem (Rosales: Rosacea hedges that were host of Eriosoma lanigerum (Hemiptera: Aphididae, a globally important aphid pest of cultivated apples. At each orchard, aphid colonies were collected and taken back to the laboratory to sample the emerging hymenopteran parasitoid Aphelinus mali (Hymenoptera: Aphelinidae. Aphid and parasitoid individuals were genotyped using species-specific microsatellite loci and genetic variability was assessed. By studying genetic variation, natural geographic barriers of the aphid pest became evident and some evidence for incipient host-plant specialization was found. However, this had no effect on the population-genetic features of its most important parasitoid. In conclusion, the lack of genetic differentiation among the parasitoids suggests the existence of a single large and panmictic population, which could parasite aphids on apple orchards and on P. coccinea hedges. The latter could thus comprise a suitable and putative refuge for parasitoids, which could be used to increase the effectiveness of biological control. Moreover, the strong geographical differentiation of the aphid suggests local reinfestations occur mainly from other apple orchards with only low reinfestation from P

  7. Concentrations of Semivolatile Organic Compounds Associated with African Dust Air Masses in Mali, Cape Verde, Trinidad and Tobago, and the U.S. Virgin Islands, 2001-2008

    Science.gov (United States)

    Garrison, Virginia H.; Foreman, William T.; Genualdi, Susan A.; Majewski, Michael S.; Mohammed, Azad; Simonich, Staci Massey

    2011-01-01

    Every year, billions of tons of fine particles are eroded from the surface of the Sahara Desert and the Sahel of West Africa, lifted into the atmosphere by convective storms, and transported thousands of kilometers downwind. Most of the dust is carried west to the Americas and the Caribbean in the Saharan Air Layer (SAL). Dust air masses predominately impact northern South America during the Northern Hemisphere winter and the Caribbean and Southeastern United States in summer. Dust concentrations vary considerably temporally and spatially. In a dust source region (Mali), concentrations range from background levels of 575 micrograms per cubic meter (mu/u g per m3) to 13,000 mu/u g per m3 when visibility degrades to a few meters (Gillies and others, 1996). In the Caribbean, concentrations of 200 to 600 mu/u g per m3 in the mid-Atlantic and Barbados (Prospero and others, 1981; Talbot and others, 1986), 3 to 20 mu/u g per m3 in the Caribbean (Prospero and Nees, 1986; Perry and others, 1997); and >100 mu/u g per m3 in the Virgin Islands (this dataset) have been reported during African dust conditions. Mean dust particle size decreases as the SAL traverses from West Africa to the Caribbean and Americas as a result of gravitational settling. Mean particle size reaching the Caribbean is <1 micrometer (mu/u m) (Perry and others, 1997), and even finer particles are carried into Central America, the Southeastern United States, and maritime Canada. Particles less than 2.5 mu/u m diameter (termed PM2.5) can be inhaled deeply into human lungs. A large body of literature has shown that increased PM2.5 concentrations are linked to increased cardiovascular/respiratory morbidity and mortality (for example, Dockery and others, 1993; Penn and others, 2005).

  8. Identification and Characterization of CRF02_AG, CRF06_cpx, and CRF09_cpx Recombinant Subtypes in Mali, West Africa

    Science.gov (United States)

    Koita, Ousmane; Dabitao, Djeneba; Dao, Sounkalo; Ibrah, Mahamadou; Sogoba, Dramane; Dewar, Robin L.; Berg, Steve C.; Jiang, Min-Kang; Parta, Mark; Washington, Janice A.; Polis, Michael A.; Lane, H. Clifford; Tounkara, Anatole

    2009-01-01

    Abstract Multiple HIV-1 subtypes and circulating recombinant forms (CRFs) are known to cocirculate in Africa. In West Africa, the high prevalence of CRF02_AG, and cocirculation of subtype A, CRF01_AE, CRF06_cpx, and other complex intersubtype recombinants has been well documented. Mali, situated in the heart of West Africa, is likely to be affected by the spread of recombinant subtypes. However, the dynamics of the spread of HIV-1 recombinant subtypes as well as nonrecombinant HIV-1 group M subtypes in this area have not been systematically assessed. Herein, we undertook genetic analyses on full-length env sequences derived from HIV-1-infected individuals living in the capital city of Mali, Bamako. Of 23 samples we examined, 16 were classified as CRF02_AG and three had a subsubtype A3. Among the remaining HIV-1 strains, CRF06_cpx and CRF09_cpx were each found in two patients. Comparison of phylogenies for six matched pol and full-length env sequences revealed that two strains had discordant subtype/CRF designations between the pol and env regions: one had A3polCRF02_AGenv and the other had CRF02_AGpolA3env. Taken together, our study demonstrated the high prevalence of CRF02_AG and complexity of circulating HIV-1 strains in Mali. It also provided evidence of ongoing virus evolution of CRF02_AG, as illustrated by the emergence of more complex CRF02_AG/A3 intersubtype recombinants in this area. PMID:19182920

  9. X-ray structure of MalY from Escherichia coli: a pyridoxal 5′-phosphate-dependent enzyme acting as a modulator in mal gene expression

    OpenAIRE

    Clausen, Tim; Schlegel, Anja; Peist, Ralf; Schneider, Eva; Steegborn, Clemens; Chang, Yuh-Shin; Haase, Andrea; Bourenkov, Gleb P.; Bartunik, Hans D.; Boos, Winfried

    2000-01-01

    MalY represents a bifunctional pyridoxal 5′-phosphate-dependent enzyme acting as a β–cystathionase and as a repressor of the maltose regulon. Here we present the crystal structures of wild-type and A221V mutant protein. Each subunit of the MalY dimer is composed of a large pyridoxal 5′-phosphate-binding domain and a small domain similar to aminotransferases. The structural alignment with related enzymes identifies residues that are generally responsible for β–lyase activity and depicts a uniq...

  10. Protection des cultures à l'aide de la haie morte et de la haie vive dans la région de Ségou, au Mali

    OpenAIRE

    Levasseur, V.; Olivier, A.; Niang, A.

    2009-01-01

    Crop Protection with the Help of Dead and Live Fences in the Segou Region, in Mali. In the Segou region, in Mali, market crop production during the dry season is increasing. This type of production needs to be protected from livestock, which roams freely during the dry season. Three types of fences are used by farmers in order to protect their plots: dead fence, which is made of crop residues or branches from thorny trees and shrubs; traditional live fence, most often consisting of euphorbia ...

  11. Studying Geology of Central Texas through Web-Based Virtual Field Trips

    Science.gov (United States)

    Chan, C.; Khan, S. D.; Wellner, J. S.

    2007-12-01

    Each year over 2500 students, mainly non-science majors, take introductory geology classes at the University of Houston. Optional field trips to Central Texas for these classes provide a unique learning opportunity for students to experience geologic concepts in a real world context. The field trips visit Enchanted Rock, Inks Lake, Bee Cave Road, Lion Mountain, and Slaughter Gap. Unfortunately, only around 10% of our students participate in these field trips. We are developing a web-based virtual field trip for Central Texas to provide an additional effective learning experience for students in these classes. The module for Enchanted Rock is complete and consists of linked geological maps, satellite imagery, digital elevation models, 3-D photography, digital video, and 3-D virtual reality visualizations. The ten virtual stops focus on different geologic process and are accompanied by questions and answers. To test the efficacy of the virtual field trip, we developed a quiz to measure student learning and a survey to evaluate the website. The quiz consists of 10 questions paralleling each stop and information on student attendance on the Central Texas field trip and/or the virtual field trip. From the survey, the average time spent on the website was 26 minutes, and overall the ratings of the virtual field trip were positive. Most noticeably students responded that the information on the website was relevant to their class and that the pictures, figures, and animations were essential to the website. Although high correlation coefficients between responses were expected for some questions (i.e., 0.89 for "The content or text of the website was clear" and "The information on the website was easy to read"), some correlations were less expected: 0.77 for "The number of test questions was appropriate" and "The information on the website was easy to read," and 0.70 for "The test questions reinforced the material presented on the website" and "The information on the

  12. New insight into genes in association with asthma: literature-based mining and network centrality analysis

    Institute of Scientific and Technical Information of China (English)

    LIANG Rui; WANG Lei; WANG Gang

    2013-01-01

    Background Asthma is a heterogeneous disease for which a strong genetic basis has been firmly established.Until now no studies have been undertaken to systemically explore the network of asthma-related genes using an internally developed literature-based discovery approach.This study was to explore asthma-related genes by using literaturebased mining and network centrality analysis.Methods Literature involving asthma-related genes were searched in PubMed from 2001 to 2011.Integration of natural language processing with network centrality analysis was used to identify asthma susceptibility genes and their interaction network.Asthma susceptibility genes were classified into three functional groups by gene ontology (GO) analysis and the key genes were confirmed by establishing asthma-related networks and pathways.Results Three hundred and twenty-six genes related with asthma such as IGHE (IgE),interleukin (IL)-4,5,6,10,13,17A,and tumor necrosis factor (TNF)-alpha were identified.GO analysis indicated some biological processes (developmental processes,signal transduction,death,etc.),cellular components (non-structural extracellular,plasma membrane and extracellular matrix),and molecular functions (signal transduction activity) that were involved in asthma.Furthermore,22 asthma-related pathways such as the Toll-like receptor signaling pathway,hematopoietic cell lineage,JAK-STAT signaling pathway,chemokine signaling pathway,and cytokine-cytokine receptor interaction,and 17 hub genes,such as JAK3,CCR1-3,CCR5-7,CCR8,were found.Conclusions Our study provides a remarkably detailed and comprehensive picture of asthma susceptibility genes and their interacting network.Further identification of these genes and molecular pathways may play a prominent role in establishing rational therapeutic approaches for asthma.

  13. Population-based study of central post-stroke pain in Rimini district, Italy

    Directory of Open Access Journals (Sweden)

    Raffaeli W

    2013-09-01

    Full Text Available William Raffaeli,1 Cristina E Minella,2 Francesco Magnani,3 Donatella Sarti3 1ISAL Foundation, Institute for Research on Pain, Torre Pedrera, Rimini, Italy 2Pain Therapy Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy 3Department of Pain Therapy and Palliative Care, Infermi Hospital, Rimini, Italy Abstract: Central post-stroke pain (CPSP is still an underestimated complication of stroke, resulting in impaired quality of life and, in addition to the functional and cognitive consequences of stroke, the presence of CPSP may be associated with mood disorders, such as depression, anxiety, and sleep disturbances. This type of pain may also impair activities of daily living and further worsen quality of life, negatively influencing the rehabilitation process. The prevalence of CSPS in the literature is highly variable (1%–12% according to different studies, and this variability could be influenced by selection criteria and the different ethnic populations being investigated. With this scenario in mind, we performed a population-based study to assess the prevalence of CPSP and its main features in a homogeneous health district (Rimini, Italy, including five hospitals for a total population of 329,970 inhabitants. From 2008 to 2010, we selected 1,494 post-stroke patients and were able to interview 660 patients, 66 (11% of whom reported pain with related tactile and thermal hyperesthesia, accompanied by needle puncture, tingling, swelling, and pressure sensations. Patients reported motor impairment and disability, which influenced their working ability, rehabilitation, and social life. Despite this severe pain state, there was a high percentage of patients who did not receive adequate treatment for pain. Keywords: stroke, central post-stroke pain, disability

  14. Serosurveillance for antibodies to rinderpest and peste de petits ruminants in bovins and small ruminants in Mali

    International Nuclear Information System (INIS)

    567 sera from 58 herds of small ruminants showed a very low prevalence of rinderpest antibodies (2 sera positive). The prevalence of antibodies to peste des petits ruminants (PPR) was very high and in the region of Segou only 7 herds were negative. The study of bovine sera included 436 sera from 15 herds with a low antibody prevalence to rinderpest. The prevalence of antibodies to rinderpest was very low (8 positive sera). These results would indicate that in Mali PPR infection in small ruminants only very occasionally infects cattle and would have a negligible effect on a rinderpest vaccination programme. (author). 3 refs, 9 tabs

  15. Parameters inversion of high central core rockfill dams based on a novel genetic algorithm

    Institute of Scientific and Technical Information of China (English)

    ZHOU Wei; LI ShaoLin; MA Gang; CHANG XiaoLin; MA Xing; ZHANG Chao

    2016-01-01

    Parameters identification of rockfill materials is a crucial issue for high rockfill dams.Because of the scale effect,random sampling and sample disturbance,it is difficult to obtain the actual mechanical properties of rockfill from laboratory tests.Parameters inversion based on in situ monitoring data has been proven to be an efficient method for identifying the exact parameters of the rockfill.In this paper,we propose a modified genetic algorithm to solve the high-dimension multimodal and nonlinear optimal parameters inversion problem.A novel crossover operator based on the sum of differences in gene fragments (SoDX) is proposed,inspired by the cloning of superior genes in genetic engineering.The crossover points are selected according to the difference in the gene fragments,defining the adaptive length.The crossover operator increases the speed and accuracy of algorithm convergence by reducing the inbreeding and enhancing the global search capability of the genetic algorithm.This algorithm is compared with two existing crossover operators.The modified genetic algorithm is then used in combination with radial basis function neural networks (RBFNN) to perform the parameters back analysis of a high central earth core rockfill dam.The settlements simulated using the identified parameters show good agreement with the monitoring data,illustrating that the back analysis is reasonable and accurate.The proposed genetic algorithm has considerable superiority for nonlinear multimodal parameter identification problems.

  16. The PCR-Based Diagnosis of Central Nervous System Tuberculosis: Up to Date

    Directory of Open Access Journals (Sweden)

    Teruyuki Takahashi

    2012-01-01

    Full Text Available Central nervous system (CNS tuberculosis, particularly tuberculous meningitis (TBM, is the severest form of Mycobacterium tuberculosis (M.Tb infection, causing death or severe neurological defects in more than half of those affected, in spite of recent advancements in available anti-tuberculosis treatment. The definitive diagnosis of CNS tuberculosis depends upon the detection of M.Tb bacilli in the cerebrospinal fluid (CSF. At present, the diagnosis of CNS tuberculosis remains a complex issue because the most widely used conventional “gold standard” based on bacteriological detection methods, such as direct smear and culture identification, cannot rapidly detect M.Tb in CSF specimens with sufficient sensitivity in the acute phase of TBM. Recently, instead of the conventional “gold standard”, the various molecular-based methods including nucleic acid amplification (NAA assay technique, particularly polymerase chain reaction (PCR assay, has emerged as a promising new method for the diagnosis of CNS tuberculosis because of its rapidity, sensitivity and specificity. In addition, the innovation of nested PCR assay technique is worthy of note given its contribution to improve the diagnosis of CNS tuberculosis. In this review, an overview of recent progress of the NAA methods, mainly highlighting the PCR assay technique, was presented.

  17. CFD Based Study of Heterogeneous Microclimate in a Typical Chinese Greenhouse in Central China

    Institute of Scientific and Technical Information of China (English)

    WANG Xiao-wei; LUO Jin-yao; LI Xiao-ping

    2013-01-01

    Indoor microclimate is important for crop production and quality in greenhouse cultivation. This paper focuses on microclimate study based on a computational fluid dynamics (CFD) model of a typical plastic greenhouse (with a sector shape vertical cross-section) popularly used in central China. A radiation model is added into the CFD model so as to simulate coupling of convective transfers and radiative exchanges at the cover and the roof, instead of using the usual coupling approach based on energy balance. In addition, a fractal permeability model is innovatively adopted in the modeling of the crop canopy. Compared the numerical results with measured experimental data, the model simulation is proved with success. This model then is used to explore the microclimate variable distributions in the greenhouse. It shows that the airflow pattern, temperature and humidity profiles are different from those in a sawtooth Mediterranean-type greenhouse. The study suggests that this deliberately developed CFD model can be served as a useful tool in macroclimate research and greenhouse design investigating.

  18. Status of Thyroid Disorders in Central Nepal: A Tertiary Care Hospital Based Study

    Directory of Open Access Journals (Sweden)

    RV Mahato

    2015-03-01

    Full Text Available Background: Nepal is a Himalayan, landlocked country surrounded by India and China. It is endemic for iodine deficiency disease. Thyroiddysfunction is major health problem among the Nepalese people. Its prevalence increases with age. Screening of thyroid disease is advised inhigh risk population. Objectives: To find out the prevalence of thyroid dysfunction among subjects who attended Biochemistry Departmentof Tribhuwan University Teaching Hospital, Kathmandu, Nepal. Material and Methods: This is a hospital based retrospective studyconducted in the Department of Biochemistry Tribhuwan University Teaching Hospital, Institute of Medicine. This study was designed toinvestigate status of thyroid dysfunction in central Nepal. A total of 5230 cases from all over Nepal were studied in a single year. Blood sampleswere collected, serum separated and thyroid hormones (fT3, fT4 and TSH were assayed by Vitros ECIQ analyser Ortho Clinical DiagonosticsUSA. Result and discussion: Among 5230 subjects prevalence of thyroid dysfunction was 29.0% with subclinical hypothyroidism17%,hypothyroidism 8%, hyperthyroidism 3%, subclinical hyperthyroidism1% and euthyroidism 71%.Higher prevalence was seen in the age group31-45. Conclusion: This study revealed that subclinical and overt hypothyroidism is preponderant followed by sub clinical hyperthyroidism.Females are more vulnerable to the thyroid dysfunction. Since it is a hospital based study, the prevalence of thyroid dysfunction may not beapplicable. So an extensive demographic survey should be done to provide accurate data of thyroid dysfunction in the general population

  19. Central retinal vein occlusion: A review of current Evidence-based treatment options

    Directory of Open Access Journals (Sweden)

    Amy Patel

    2016-01-01

    Full Text Available A central retinal vein occlusion (CRVO can induce an ischemic and hypoxic state with resulting sequelae of macular edema and neovascularization. Many treatment options have been studied. Our review aims to investigate the safety and efficacy of the multiple treatment options of CRVO. A PubMed and Cochrane literature search was performed. Well-controlled randomized clinical trials that demonstrated strong level 1 evidence-based on the rating scale developed by the British Centre for Evidence-Based Medicine were included. Seven clinical trials met inclusion criteria to be included in this review. These included studies that investigated the safety and efficacy of retinal photocoagulation (1 study, intravitreal steroid treatment (2 studies, and antivascular endothelial growth factor treatment (4 studies for the treatment of CRVO. In addition, studies evaluating surgical treatment options for CRVO were also included. Many treatment modalities have been demonstrated to be safe and efficacious in the treatment of CRVO. These treatment options offer therapeutic benefits for patients and clinically superior visual acuity and perhaps the quality of life after suffering from a CRVO.

  20. Appropriate training and retention of community doctors in rural areas: a case study from Mali

    Directory of Open Access Journals (Sweden)

    Coulibaly Seydou

    2008-11-01

    Full Text Available Abstract Background While attraction of doctors to rural settings is increasing in Mali, there is concern for their retention. An orientation course for young practicing rural doctors was set up in 2003 by a professional association and a NGO. The underlying assumption was that rurally relevant training would strengthen doctors' competences and self-confidence, improve job satisfaction, and consequently contribute to retention. Methods Programme evaluation distinguished trainees' opinions, competences and behaviour. Data were collected through participant observation, group discussions, satisfaction questionnaires, a monitoring tool of learning progress, and follow up visits. Retention was assessed for all 65 trainees between 2003 and 2007. Results and discussion The programme consisted of four classroom modules – clinical skills, community health, practice management and communication skills – and a practicum supervised by an experienced rural doctor. Out of the 65 trained doctors between 2003 and 2007, 55 were still engaged in rural practice end of 2007, suggesting high retention for the Malian context. Participants viewed the training as crucial to face technical and social problems related to rural practice. Discussing professional experience with senior rural doctors contributed to socialisation to novel professional roles. Mechanisms underlying training effects on retention include increased self confidence, self esteem as rural doctor, and sense of belonging to a professional group sharing a common professional identity. Retention can however not be attributed solely to the training intervention, as rural doctors benefit from other incentives and support mechanisms (follow up visits, continuing training, mentoring... affecting job satisfaction. Conclusion Training increasing self confidence and self esteem of rural practitioners may contribute to retention of skilled professionals in rural areas. While reorientations of curricula in

  1. Results of an action-research on epilepsy in rural Mali.

    Directory of Open Access Journals (Sweden)

    Elisa Bruno

    Full Text Available PURPOSE: To evaluate the RARE (Réseau Action-Recherche sur l'Epilepsie program, a model of managing and treating people with epilepsy (PWE at a primary health-care level in rural areas of Mali, we assessed treatment efficacy and compliance of patients who underwent the first year follow-up. METHODS: A network of rural general practitioners (GPs settled in six rural districts of the regions of Koulikoro, Segou and Sikasso, was involved in the diagnosis, evaluation and monitoring of all the identified PWE and in the distribution of phenobarbital (PB. All the participants were included in a prospective database and followed-up by GPs at 4 months intervals during the first year. Seizure frequency, treatment doses and appearance of adverse events (AEs were systematically recorded. Efficacy was evaluated in terms of reduction of seizures frequency while noncompliance in terms of time to study withdrawal for any cause. KEY FINDINGS: 596 patients treated with PB were included in the analysis. Of these, 74.0% completed the first year follow-up. At the final visit, 59.6% were seizure-free: 31.0% for 12 months, 10.2% for 8 months and 18.4% for 4 months. Adults and patients with convulsive seizures were the most drug-resistant (p<0.002. Few AEs were recorded. The multivariate analysis showed that being a woman, presenting convulsive seizures, having more than 5 seizures/month and had never be treated were predictors of withdrawal (p ≤ 0.05 at 12 months. SIGNIFICANCE: This study showed a good response and compliance to the treatment and allowed the identification of some factors associated with failure of management in a setting very near to clinical practice. Awareness campaigns are needed to assure a broader accessibility to treatment and to improve the compliance and continuity with treatment programs.

  2. Medicinal Plants Used in Mali for the Treatment of Malaria and Liver Diseases.

    Science.gov (United States)

    Haidara, Mahamane; Bourdy, Geneviève; De Tommasi, Nunziatina; Braca, Alessandra; Traore, Korotoumou; Giani, Sergio; Sanogo, Rokia

    2016-03-01

    Today, ethno-pharmacology is a very important resource in order to discover new therapies for the current diseases. Moreover, another good justification for the ethno-pharmacological approach is to obtain new, effective, less expensive and simple therapies, limiting at the same time the cost of pharmaceutical research. Two major anti-malarial drugs widely used today, i.e. quinine and artemisinin, came respectively from Peruvian and Chinese ancestral treatments reported in the traditional medicines. In this contest, there is an urgent need for the discovery of new drugs, due to the critical epidemiological situation of this disease and to the growth of resistances. In Mali, malaria and liver diseases remain one of the leading public health problems. Many medicinal plants are often used, in local traditional medicine, for the treatment at the same time of malaria and liver diseases, including hepatic syndromes, jaundice, hepatitis and other hepatic disorders. Moreover, in the local language Bamanan, the word "Sumaya" is used both for malaria and some liver diseases. In addition, we noted that some of the improved traditional phytomedicines produced by the Department of Traditional Medicine are prescribed by modern doctors both for malaria and liver diseases. In this review, pharmacological, toxicological and phytochemical data on Argemone mexicana L. (Papaveraceae), Cochlospermum tinctorium Perr. ex A. Rich (Cochlospermaceae), Combretum micranthum G.Don (Combretaceae), Entada africana Guillet Perr. (Mimosaceae), Erythrina senegalensis A. DC (Fabaceae), Mitragyna inermis (Willd) Kuntze (Rubiaceae), Nauclea latifolia Smith syn. Sarcocephalus latifolius (Smith) Bruce (Rubiaceae), Securidaca longepedunculata Fresen (Polygalaceae), Trichilia emetica Vahl. (Meliaceae), and Vernonia colorata (Willd) Drake (Asteraceae) are reported. Some of the collected data could be used to improve the actual herbal drugs and to propose new phytomedicines for the management of malaria and

  3. Characteristics and Composition of Atmospheric Aerosols in Phimai, Central Thailand During BASE-ASIA

    Science.gov (United States)

    Li, Can; Tsay, Si-Chee; Hsu, N. Christina; Kim, Jin Young; Howell, Steven G.; Huebert, Barry J.; Ji, Qiang; Jeong, Myeong-Jae; Wang, Sheng-Hsiang; Hansell, Richard A.; Bell, Shaun W.

    2012-01-01

    Popular summary: Atmospheric aerosols play an important role in the Earth's climate system, and can also have adverse effects on air quality and human health. The environmental impacts of aerosols, on the other hand, are highly regional, since their temporal/spatial distribution is inhomogeneous and highly depends on the regional emission sources. To better understand the effects of aerosols, intensive field experiments are necessary to characterize the chemical and physical properties on a region-by-region basis. From late February to early May in 2006, NASA/GSFC's SMARTLabs facility was deployed at a rural site in central Thailand, Southeast Asia, to conduct a field experiment dubbed BASE-ASIA (Biomass-burning Aerosols in South East-Asia: Smoke Impact Assessment). The group was joined by scientists from the University of Hawaii and other regional institutes. Comprehensive measurements were made during the experiment, including aerosol chemical composition, optical and microphysical properties, as well as surface energetics and local . meteorology. This study analyzes part of the data from the BASE-ASIA experiment. It was found that, even for the relatively remote rural site, the aerosol loading was still substantial. Besides agricultural burning in the area, industrial pollution near the Bangkok metropolitan area, about 200 km southeast of the site, and even long-range transport from China, also contribute to the area's aerosol loading. The results indicate that aerosol pollution has developed into a regional problem for northern Indochina, and may become more severe as the region's population and economy continue to grow. Abstract: Comprehensive measurements of atmospheric aerosols were made in Phimai, central Thailand (15.l83 N, 102.565 E, elevation: 206 m) during the BASE-ASIA field experiment from late February to early May in 2006. The observed aerosol loading was sizable for this rural site (mean aerosol scattering: 108 +/- 64 Mm(exp -1); absorption: 15

  4. Status and future transition of rapid urbanizing landscape in central Western Ghats - CA based approach

    Science.gov (United States)

    Bharath, S..; Rajan, K. S.; Ramachandra, T. V.

    2014-11-01

    The land use changes in forested landscape are highly complex and dynamic, affected by the natural, socio-economic, cultural, political and other factors. The remote sensing (RS) and geographical information system (GIS) techniques coupled with multi-criteria evaluation functions such as Markov-cellular automata (CA-Markov) model helps in analysing intensity, extent and future forecasting of human activities affecting the terrestrial biosphere. Karwar taluk of Central Western Ghats in Karnataka state, India has seen rapid transitions in its forest cover due to various anthropogenic activities, primarily driven by major industrial activities. A study based on Landsat and IRS derived data along with CA-Markov method has helped in characterizing the patterns and trends of land use changes over a period of 2004-2013, expected transitions was predicted for a set of scenarios through 2013-2022. The analysis reveals the loss of pristine forest cover from 75.51% to 67.36% (1973 to 2013) and increase in agriculture land as well as built-up area of 8.65% (2013), causing impact on local flora and fauna. The other factors driving these changes are the aggregated level of demand for land, local and regional effects of land use activities such as deforestation, improper practices in expansion of agriculture and infrastructure development, deteriorating natural resources availability. The spatio temporal models helped in visualizing on-going changes apart from prediction of likely changes. The CA-Markov based analysis provides us insights into the localized changes impacting these regions and can be useful in developing appropriate mitigation management approaches based on the modelled future impacts. This necessitates immediate measures for minimizing the future impacts.

  5. Centrality measures in networks based on nodes attributes, long-range interactions and group influence

    CERN Document Server

    Aleskerov, F; Shvydun, S

    2016-01-01

    We propose a new method for assessing agents influence in network structures, which takes into consideration nodes attributes, individual and group influences of nodes, and the intensity of interactions. This approach helps us to identify both explicit and hidden central elements which cannot be detected by classical centrality measures or other indices.

  6. 3D VISION-BASED DIETARY INSPECTION FOR THE CENTRAL KITCHEN AUTOMATION

    Directory of Open Access Journals (Sweden)

    Yue-Min Jiang

    2014-12-01

    Full Text Available This paper proposes an intelligent and automatic dietary inspection system which can be applied to the dietary inspection for the application of central kitchen automation. The diet specifically designed for the patients are required with providing personalized diet such as low sodium intake or some necessary food. Hence, the proposed system can benefit the inspection process that is often performed manually. In the proposed system, firstly, the meal box can be detected and located automatically with the vision-based method and then all the food ingredients can be identified by using the color and LBP-HF texture features. Secondly, the quantity for each of food ingredient is estimated by using the image depth information. The experimental results show that the dietary inspection accuracy can approach 80%, dietary inspection efficiency can reach1200ms, and the food quantity accuracy is about 90%. The proposed system is expected to increase the capacity of meal supply over 50% and be helpful to the dietician in the hospital for saving the time in the diet inspection process.

  7. Incidence and mechanism of central pontine myelinolysis based on analysis of MRI images and risk factors

    Energy Technology Data Exchange (ETDEWEB)

    Kondo, Masato [Akita Univ. (Japan). School of Medicine

    2000-02-01

    In this study, the incidence of central pontine myelinolysis (CPM)-like lesions on MRI images was studied in 1917 subjects, 1,500 of which were psychiatric patients and 417 were patients attending a brain health examination. The CPM-like lesions were first classified into four groups based on the characteristics of their MRI images: group 1 showed symmetrical lesions on both T1 low and T2 high images and were considered to be typical CPM; group 2 showed symmetrical high intensity lesions only on T2 images; group 3 had asymmetrical lesions only on T2 images; and group 4 had asymmetrical lesions on both T1 low and T2 high images. Furthermore, the relationships of each group with particular risk factors, such as alcoholism, hypertension, hyperlipidemia were statistically analysed. The cause of CPM-like features in the MRI images were discussed. Among our subjects, the incidence of CPM-like lesions was 3.8%, and that of group 1 was 1.2%. Significant correlations between group 1 and alcoholism, and group 3 and 4 with brain ischemic lesions were observed. A previous hypothesis that group 2 may be a premature state of CPM is not supported by our results. (author)

  8. CO2 Total Column Variability From Ground-Based FTIR Measurements Over Central Mexico

    Science.gov (United States)

    Baylon, J. L.; Stremme, W.; Plaza, E.; Bezanilla, A.; Grutter, M.; Hase, F.; Blumenstock, T.

    2014-12-01

    There are now several space missions dedicated to measure greenhouse gases in order to improve the understanding of the carbon cycle. Ground based measurement sites are of great value in the validation process, however there are only a few stations in tropical latitudes. We present measurements of solar-absorption infrared spectra recorded on two locations over Central Mexico: the High-Altitude Station Altzomoni (19.12 N, 98.65 W), located in the Izta-Popo National Park outside of Mexico City; and the UNAM's Atmospheric Observatory (19.32 N, 99.17 W) in Mexico City. These measurements were performed using a high resolution Fourier transform infrared spectrometer FTIR (Bruker, HR 120/5) at Altzomoni and a moderate resolution FTIR (Bruker, Vertex 80) within the city. In this work, we present the first results for total vertical columns of CO2 derived from near-infrared spectra recorded at both locations using the retrieval code PROFFIT. We present the seasonal cycle and variability from the measurements, as well as the full diagnostics of the retrieval in order assess its quality and discuss the differences of both instruments and locations (altitudes, urban vs remote). This work aims to contribute to generate high quality datasets for satellite validation.

  9. The Contribution of a Central Pattern Generator in a Reflex-Based Neuromuscular Model

    Directory of Open Access Journals (Sweden)

    Florin eDzeladini

    2014-06-01

    Full Text Available Although the concept of central pattern generators (CPGs controlling locomotion in vertebrates is widely accepted, the presence of specialized CPGs in human locomotion is still a matter of debate. An interesting numerical model developed in the 90s' demonstrated the important role CPGs could play in human locomotion, both in terms of stability against perturbations, and in terms of speed control. Recently, a reflex-based neuro-musculo-skeletal model has been proposed, showing a level of stability to perturbations similar to the previous model, without any CPG components. Although exhibiting striking similarities with human gaits, the lack of CPG makes the control of speed/step length in the model difficult. In this paper, we hypothesize that a CPG component will offer a meaningful way of controlling the locomotion speed. After introducing the CPG component in the reflex model, and taking advantage of the resulting properties, a simple model for gait modulation is presented.The results highlight the advantages that a feedforward component can have in terms of gait modulation.

  10. Incidence and mechanism of central pontine myelinolysis based on analysis of MRI images and risk factors

    International Nuclear Information System (INIS)

    In this study, the incidence of central pontine myelinolysis (CPM)-like lesions on MRI images was studied in 1917 subjects, 1,500 of which were psychiatric patients and 417 were patients attending a brain health examination. The CPM-like lesions were first classified into four groups based on the characteristics of their MRI images: group 1 showed symmetrical lesions on both T1 low and T2 high images and were considered to be typical CPM; group 2 showed symmetrical high intensity lesions only on T2 images; group 3 had asymmetrical lesions only on T2 images; and group 4 had asymmetrical lesions on both T1 low and T2 high images. Furthermore, the relationships of each group with particular risk factors, such as alcoholism, hypertension, hyperlipidemia were statistically analysed. The cause of CPM-like features in the MRI images were discussed. Among our subjects, the incidence of CPM-like lesions was 3.8%, and that of group 1 was 1.2%. Significant correlations between group 1 and alcoholism, and group 3 and 4 with brain ischemic lesions were observed. A previous hypothesis that group 2 may be a premature state of CPM is not supported by our results. (author)

  11. Base of Principal Aquifer for the Elkhorn-Loup Model Area, North-Central Nebraska

    Science.gov (United States)

    McGuire, V.L.; Peterson, Sean M.

    2008-01-01

    In Nebraska, the water managers in the Natural Resources Districts and the Nebraska Department of Natural Resources are concerned with the effect of ground-water withdrawal on the availability of surface water and the long-term effects of ground-water withdrawal on ground- and surface-water resources. In north-central Nebraska, in the Elkhorn and Loup River Basins, ground water is used for irrigation, domestic supply, and public supply; surface water is used in this area for irrigation, recreation, and hydropower production. In recognition of these sometimes competing ground- and surface-water uses in the Elkhorn and Loup River Basins, the U.S. Geological Survey, the Lewis and Clark Natural Resources District, the Lower Elkhorn Natural Resources District, the Lower Loup Natural Resources District, the Lower Niobrara Natural Resources District, the Lower Platte North Natural Resources District, the Middle Niobrara Natural Resources District, the Upper Elkhorn Natural Resources District, and the Upper Loup Natural Resources District agreed to cooperatively study water resources in the Elkhorn and Loup River Basins. The goals of the overall study were to construct and calibrate a regional ground-water flow model of the area and to use that flow model as a tool to assess current and future effects of ground-water irrigation on stream base flow and to help develop long-term water-resource management strategies for this area, hereafter referred to as the Elkhorn-Loup model area. The Elkhorn-Loup model area covers approximately 30,800 square miles, and extends from the Niobrara River in the north to the Platte River in the south. The western boundary of the Elkhorn-Loup model area coincides with the western boundary of the Middle Niobrara, Twin Platte, and Upper Loup Natural Resources Districts; the eastern boundary coincides with the approximate location of the western extent of glacial till in eastern Nebraska. The principal aquifer in most of the Elkhorn-Loup model

  12. Effect of Seasonality and Ecological Factors on the Prevalence of the Four Malaria Parasite Species in Northern Mali

    Directory of Open Access Journals (Sweden)

    Ousmane A. Koita

    2012-01-01

    Full Text Available Background. We performed 2 cross-sectional studies in Ménaka in the Northeastern Mali across 9 sites in different ecological settings: 4 sites have permanent ponds, 4 without ponds, and one (City of Ménaka has a semipermanent pond. We enrolled 1328 subjects in May 2004 (hot dry season and 1422 in February 2005 (cold dry season after the rainy season. Objective. To examine the seasonality of malaria parasite prevalence in this dry northern part of Mali at the edge of the Sahara desert. Results. Slide prevalence was lower in hot dry than cold dry season (4.94 versus 6.85%, P=0.025. Gametocyte rate increased to 0.91% in February. Four species were identified. Plasmodium falciparum was most prevalent (74.13 and 63.72%. P. malariae increased from 9.38% to 22.54% in February. In contrast, prevalence of P. vivax was higher (10.31% without seasonal variation. Smear positivity was associated with splenomegaly (P=0.007. Malaria remained stable in the villages with ponds (P=0.221; in contrast, prevalence varied between the 2 seasons in the villages without ponds (P=0.004. Conclusion. Malaria was mesoendemic; 4 species circulates with a seasonal fluctuation for Plasmodium falciparum.

  13. An identification key to species in the mali complex of Aphelinus (Hymenoptera, Chalcidoidea with descriptions of three new species

    Directory of Open Access Journals (Sweden)

    Keith Hopper

    2012-05-01

    Full Text Available The Aphelinus mali complex consists of eleven described species. Monophyly of this complex is well supported by a combination of traits: (1 a single complete row of setae proximal to the linea calva of the fore wing, with a few additional setae in the angle between this row and the marginal vein; (2 linea calva open (no setae at its posterior edge; (3 head and body dark except for parts of the metasoma; (4 meso- and metacoxae dark; (5 metafemur pale, (6 metatibia dark. Species within the complex have been distinguished by color and shape of antennal segments (particularly the third funicular segment, color of legs and metasoma, and relative length of ovipositor versus mesotibia. We provide a key for identifying species in the mali complex, and describe three new species, Aphelinus glycinis sp. n., Aphelinus rhamni sp. n., and Aphelinus coreae sp. n. from material in laboratory cultures originally reared from soybean aphid in China and Korea as candidates for biological control of soybean aphid, Aphis glycines.

  14. Cotton as an entry point for soil fertility maintenance and food crop productivity in savannah agroecosystems - Evidence from a long-term experiment in southern Mali

    NARCIS (Netherlands)

    Ripoche, A.; Crétenet, M.; Corbeels, M.; Affholder, F.; Naudin, K.; Sissoko, F.; Douzet, J.M.; Tittonell, P.A.

    2015-01-01

    Given the scarcity of manure and the limited land available for fallowing, cotton cultivation with its input credit schemes is often the main entry point for nutrients in cropping systems of West Africa. In an experiment carried out during 25 years in southern Mali, the crop and soil responses to or

  15. Learning Strategies for Post-Literacy and Continuing Education in Mali, Niger, Senegal, and Upper Volta. UIE Studies on Post-Literacy and Continuing Education 2.

    Science.gov (United States)

    Dave, R. H., Ed.; And Others

    This collection contains four papers discussing the outcomes of an international research project on the concept of lifelong education and its implications for educational reforms and development in developing nations. The following papers are included: "Rural Newspapers and Other Learning Strategies for Post-Literacy and Basic Education in Mali,"…

  16. Field experiments of Anopheles gambiae attraction to local fruits/seedpods and flowering plants in Mali to optimize strategies for malaria vector control in Africa using attractive toxic sugar bait methods

    Directory of Open Access Journals (Sweden)

    Bah Sekou

    2010-09-01

    Full Text Available Abstract Background Based on recent studies in Israel demonstrating that attractive toxic sugar bait (ATSB methods can be used to decimate local anopheline and culicine mosquito populations, an important consideration is whether the same methods can be adapted and improved to attract and kill malaria vectors in Africa. The ATSB approach uses fruit or flower scent as an attractant, sugar solution as a feeding stimulant, and an oral toxin. The ATSB solutions are either sprayed on vegetation or suspended in simple bait stations, and the mosquitoes ingesting the toxic solutions are killed. As such, this approach targets sugar-feeding female and male mosquitoes. This study examines the attractiveness of African malaria vectors to local fruits/seedpods and flowering plants, key biological elements of the ATSB approach for mosquito control. Methods Three field experiments were conducted at sites in Mali. The attraction of Anopheles gambiae s.l. to 26 different local fruits and seedpods was determined at a site in the semi-arid Bandiagara District of Mali. Wire mesh glue traps with fruits/seedpods suspended on skewers inside were set along a seasonal lagoon. Seven replicates of each fruit/seedpod species were tested, with a water-soaked sponge and a sugar-soaked sponge as controls. The attraction of An. gambiae s.l. to 26 different types of flowering plants was determined at a site near Mopti in Mali. The flowering plants held in a water-filled buried container were tested using the same glue traps, with controls including water only and sugar solution. Six replicates of each selected plant type were tested on transects between rice paddies. Additional studies using CDC light traps were done to determine the relative densities and periodicity of An. gambiae s.l. attraction to branches of the most highly attractive flowering plant, branches without flowers, human odor, and candescent light. Results Of the 26 fruits and seedpods tested, 6 were attractive

  17. Modelling malaria incidence with environmental dependency in a locality of Sudanese savannah area, Mali

    Directory of Open Access Journals (Sweden)

    Demongeot Jacques

    2009-04-01

    Full Text Available Abstract Background The risk of Plasmodium falciparum infection is variable over space and time and this variability is related to environmental variability. Environmental factors affect the biological cycle of both vector and parasite. Despite this strong relationship, environmental effects have rarely been included in malaria transmission models. Remote sensing data on environment were incorporated into a temporal model of the transmission, to forecast the evolution of malaria epidemiology, in a locality of Sudanese savannah area. Methods A dynamic cohort was constituted in June 1996 and followed up until June 2001 in the locality of Bancoumana, Mali. The 15-day composite vegetation index (NDVI, issued from satellite imagery series (NOAA from July 1981 to December 2006, was used as remote sensing data. The statistical relationship between NDVI and incidence of P. falciparum infection was assessed by ARIMA analysis. ROC analysis provided an NDVI value for the prediction of an increase in incidence of parasitaemia. Malaria transmission was modelled using an SIRS-type model, adapted to Bancoumana's data. Environmental factors influenced vector mortality and aggressiveness, as well as length of the gonotrophic cycle. NDVI observations from 1981 to 2001 were used for the simulation of the extrinsic variable of a hidden Markov chain model. Observations from 2002 to 2006 served as external validation. Results The seasonal pattern of P. falciparum incidence was significantly explained by NDVI, with a delay of 15 days (p = 0.001. An NDVI threshold of 0.361 (p = 0.007 provided a Diagnostic Odd Ratio (DOR of 2.64 (CI95% [1.26;5.52]. The deterministic transmission model, with stochastic environmental factor, predicted an endemo-epidemic pattern of malaria infection. The incidences of parasitaemia were adequately modelled, using the observed NDVI as well as the NDVI simulations. Transmission pattern have been modelled and observed values were adequately

  18. Perspectives of people in Mali toward genetically-modified mosquitoes for malaria control

    Directory of Open Access Journals (Sweden)

    Famenini Shannon

    2010-05-01

    Full Text Available Abstract Background Genetically-modified (GM mosquitoes have been proposed as part of an integrated vector control strategy for malaria control. Public acceptance is essential prior to field trials, particularly since mosquitoes are a vector of human disease and genetically modified organisms (GMOs face strong scepticism in developed and developing nations. Despite this, in sub-Saharan Africa, where the GM mosquito effort is primarily directed, very little data is available on perspectives to GMOs. Here, results are presented of a qualitative survey of public attitudes to GM mosquitoes for malaria control in rural and urban areas of Mali, West Africa between the months of October 2008 and June 2009. Methods The sample consisted of 80 individuals - 30 living in rural communities, 30 living in urban suburbs of Bamako, and 20 Western-trained and traditional health professionals working in Bamako and Bandiagara. Questions were asked about the cause of malaria, heredity and selective breeding. This led to questions about genetic alterations, and acceptable conditions for a release of pest-resistant GM corn and malaria-refractory GM mosquitoes. Finally, participants were asked about the decision-making process in their community. Interviews were transcribed and responses were categorized according to general themes. Results Most participants cited mosquitoes as one of several causes of malaria. The concept of the gene was not widely understood; however selective breeding was understood, allowing limited communication of the concept of genetic modification. Participants were open to a release of pest-resistant GM corn, often wanting to conduct a trial themselves. The concept of a trial was reapplied to GM mosquitoes, although less frequently. Participants wanted to see evidence that GM mosquitoes can reduce malaria prevalence without negative consequences for human health and the environment. For several participants, a mosquito control programme was

  19. [Water contacts in dracunculiasis-infected patients in Mali: transmission risk activities].

    Science.gov (United States)

    Etard, J F; Kodio, B; Traoré, S; Audibert, M

    2002-11-01

    The aim of this study lies in the identification of human activities responsible for the transmission of the Guinea worm in an endemic village in Diema Region in Mali. Human water contacts observations started after a census followed by the implementation of a bi-monthly notification system, carried out from May to November 1993. Water contacts were noticed and observed from the mid-July to the end of November of the same year. The first case of dracunculiasis observed was randomly drawn out of a list of the families with obvious cases. The patent case activities involving either surface water, traditional wells or bore-hole water were recorded for 10 consecutive days. During this observation period, contacts made by other patients with the same water sources were also recorded. After 14 days, the case list was updated and a new case selected out of families previously selected. This cycle was repeated until the end of the study period. A "contact at risk for transmission" was defined by a close correspondence between the location of the worm's emergence and the surface of the skin exposed to water, within two weeks following emergence. Contacts were described according to water sources, activities in relation to water, date, gender and age. Observations were made on 103 patients who had 2506 activities in relation with a water body: 1132 of these activities implied a skin contact with the water. Only 133 (9%) of these water contacts were at risk for transmission, 75% took place during the months of August and September, 80% were related to surface waters and 20% to traditional wells. Woman household activities and boys games were the major activities at risk, in contrast to economic activities (watering cattle). The low proportion of "at risk activities" evaluated in this study suggests that a small number of water contacts is sufficient to maintain the transmission. The case implications of the current eradication strategy might not be sufficient alone to break

  20. Indicator minerals as guides to base metal sulphide mineralisation in Betul Belt, central India

    Indian Academy of Sciences (India)

    Biswajit Ghosh; M N Praveen

    2008-08-01

    Zn-bearing minerals that act as indicator minerals for base metal sulphide mineralization from the Proterozoic Betul Belt,central India with special emphasis on their genetic significance have been discussed.Sulphide mineralisation is hosted by the felsic volcanic rocks and has similarities with volcanic-hosted massive sulphide deposits in other parts of the world.Synvolcanic hydrothermal alteration is crudely zoned with an inner high Mg-Ca core and an outer wider envelop of Al-Fe rich mineral assemblage.Most of the prospects have strata bound,moderately to steeply dipping, multiple,sub-parallel sheet like ore bodies composed of disseminated and semi-massive to massive ores.Zn-bearing spinel,staurolite,biotite and ilmenite typically occur within the foot-wall altera- tion zones in close proximity to the sulphide mineralization.Zincian spinel is ubiquitous irrespective of the nature of alteration zone.Zincian staurolite is nearly absent in Mg-Ca alteration zones but commonly present in Al-Fe alteration zone along with zincian ilmenite.Zn-bearing biotite in intimate association with zincian spinel is generally found in Mg-Ca alteration zone and in the transition to Al-Fe alteration zone.Most of these indicator minerals can be considered as products of desulphidation of sphalerite during metamorphism.Mechanisms other than desulphidation like formation of gahnite by overstepping of the zinc saturation limit of biotite during retrogression to chlorite and formation of zincian staurolite at the expense of gahnite is also recorded.Field presence of these minerals has immense significance in exploration in Betul Belt as they occur in close spatial relationship with the sulphide rich zones and therefore act as direct vectors to ore.

  1. Implementation of Central Dogma Based Cryptographic Algorithm in Data Warehouse Architecture for Performance Enhancement

    Directory of Open Access Journals (Sweden)

    Rajdeep Chowdhury

    2015-11-01

    Full Text Available Data warehouse is a set of integrated databases deliberated to expand decision-making and problem solving, espousing exceedingly condensed data. Data warehouse happens to be progressively more accepted theme for contemporary researchers with respect to contemporary inclination towards industry and executive purview. The crucial tip of the proposed work is integrated on delivering an enhanced and an exclusive innovative model based on the intention of enhancing security measures, which at times have been found wanting and also ensuring improved accessibility using Hashing modus operandi. An unsullied algorithm was engendered using the concept of protein synthesis, prevalently studied in Genetics, that is, in the field of Biotechnology, wherein three steps are observed, namely; DNA Replication, Translation and Transcription. In the proposed algorithm, the two latter steps, that is, Translation and Transcription have been taken into account and the concept have been used for competent encryption and proficient decryption of data. Central Dogma Model is the name of the explicit model that accounts for and elucidates the course of action for Protein Synthesis using the Codons which compose the RNA and the DNA and are implicated in numerous bio–chemical processes in living organisms. It could be observed that subsequently a dual stratum of encryption and decryption mechanism has been employed for optimal security. The formulation of the immaculate Hashing modus operandi ensure that there would be considerable diminution of access time, keeping in mind the apt retrieval of all indispensable data from the data vaults. The pertinent appliance of the proposed model with enhanced security might be in its significant service in a variety of organizations where accrual of protected data is of extreme magnitude. The variety of organizations might include educational organizations, corporate houses, medical establishments, private establishments and so on

  2. Remote Sensing Based Biophysical Characterization of Tropical Deciduous Forest in Central India

    Science.gov (United States)

    Singh, R. P.; Goroshi, S.; Sharma, N. K.; Bairagi, G. D.; Sharma, R.; Jalil, P.; Jain, A.; Sonakia, A.; Parihar, J. S.

    2011-09-01

    The paper reports the measurements of biophysical parameters using field and satellite data over a tropical deciduous forest Kanha National Park (KNP), central India. Field measurement (GBH, LAI, litter, soil moisture) was carried out over ten quadrates of 0.1ha in KNP for characterization of biophysical parameters with specified measurement protocol and sampling. Satellite based remote sensing analysis (LAI, Phenology, and NPP) was carried out using multi date observations of IRS-LISS-III, IMS-1MX, SPOT-VEGETATION and EOS-MODIS instruments. Rank correlation analysis using field data collected in the selected quadrates at KNP showed Sal (Shorea robusta) is dominant forest species followed by Lendia, Jamun (Syzygium cumini), Saja, Harra and Dhawda etc. Field measurement of Sal showed GBH range from 20 cm to 170 cm. Different forest classes such as Sal; Sal mixed with Jamun, Bamboo (Dendrocalamus strictus) etc, including grasslands/scrubland were classified with overall accuracy of 85.56 percent using March, May and October multi spectral data. Sal has distinct growth characteristics (low vegetation growth/ leaf fall in March instead of May) as compared to other vegetation species. As per the Leaf Area Index (LAI) measurement using hemispherical photographs, Sal showed the highest LAI (6.95 m2/m2) during September and lowest LAI (2.63 m2/m2) during March. Overall good agreement (r= 0.79) was found between the LAI generated from LISS-III and MODIS data product. It was observed from SPOT-VEGETATION analysis that NPP varied from 8.4 tC/ha/year (dry deciduous forest) to 14.25 tC/ha/year (Moist deciduous forest) in KNP.

  3. Assessing early access to care and child survival during a health system strengthening intervention in Mali: a repeated cross sectional survey.

    Directory of Open Access Journals (Sweden)

    Ari D Johnson

    Full Text Available BACKGROUND: In 2012, 6.6 million children under age five died worldwide, most from diseases with known means of prevention and treatment. A delivery gap persists between well-validated methods for child survival and equitable, timely access to those methods. We measured early child health care access, morbidity, and mortality over the course of a health system strengthening model intervention in Yirimadjo, Mali. The intervention included Community Health Worker active case finding, user fee removal, infrastructure development, community mobilization, and prevention programming. METHODS AND FINDINGS: We conducted four household surveys using a cluster-based, population-weighted sampling methodology at baseline and at 12, 24, and 36 months. We defined our outcomes as the percentage of children initiating an effective antimalarial within 24 hours of symptom onset, the percentage of children reported to be febrile within the previous two weeks, and the under-five child mortality rate. We compared prevalence of febrile illness and treatment using chi-square statistics, and estimated and compared under-five mortality rates using Cox proportional hazard regression. There was a statistically significant difference in under-five mortality between the 2008 and 2011 surveys; in 2011, the hazard of under-five mortality in the intervention area was one tenth that of baseline (HR 0.10, p<0.0001. After three years of the intervention, the prevalence of febrile illness among children under five was significantly lower, from 38.2% at baseline to 23.3% in 2011 (PR = 0.61, p = 0.0009. The percentage of children starting an effective antimalarial within 24 hours of symptom onset was nearly twice that reported at baseline (PR = 1.89, p = 0.0195. CONCLUSIONS: Community-based health systems strengthening may facilitate early access to prevention and care and may provide a means for improving child survival.

  4. Live bird markets characterization and trading network analysis in Mali: Implications for the surveillance and control of avian influenza and Newcastle disease.

    Science.gov (United States)

    Molia, Sophie; Boly, Ismaël Ardho; Duboz, Raphaël; Coulibaly, Boubacar; Guitian, Javier; Grosbois, Vladimir; Fournié, Guillaume; Pfeiffer, Dirk Udo

    2016-03-01

    Live bird markets (LBMs) play an important role in the transmission of avian influenza (AI) and Newcastle disease (ND) viruses in poultry. Our study had two objectives: (1) characterizing LBMs in Mali with a focus on practices influencing the risk of transmission of AI and ND, and (2) identifying which LBMs should be targeted for surveillance and control based on properties of the live poultry trade network. Two surveys were conducted in 2009-2010: a descriptive study in all 96 LBMs of an area encompassing approximately 98% of the Malian poultry population and a network analysis study in Sikasso county, the main poultry supplying county for the capital city Bamako. Regarding LBMs' characteristics, risk factors for the presence of AI and ND viruses (being open every day, more than 2 days before a bird is sold, absence of zoning to segregate poultry-related work flow areas, waste removal or cleaning and disinfecting less frequently than on a daily basis, trash disposal of dead birds and absence of manure processing) were present in 80-100% of the LBMs. Furthermore, LBMs tended to have wide catchment areas because of consumers' preference for village poultry meat, thereby involving a large number of villages in their supply chain. In the poultry trade network from/to Sikasso county, 182 traders were involved and 685 links were recorded among 159 locations. The network had a heterogeneous degree distribution and four hubs were identified based on measures of in-degrees, out-degrees and betweenness: the markets of Medine and Wayerma and the fairs of Farakala and Niena. These results can be used to design biosecurity-improvement interventions and to optimize the prevention, surveillance and control of transmissible poultry diseases in Malian LBMs. Further studies should investigate potential drivers (seasonality, prices) of the poultry trade network and the acceptability of biosecurity and behavior-change recommendations in the Malian socio-cultural context. PMID

  5. A quantitative synthesis of the medicinal ethnobotany of the Malinké of Mali and the Asháninka of Peru, with a new theoretical framework

    Science.gov (United States)

    Bletter, Nathaniel

    2007-01-01

    Background Although ethnomedically and taxonomically guided searches for new medicinal plants can improve the percentage of plants found containing active compounds when compared to random sampling, ethnobotany has fulfilled little of its promise in the last few decades to deliver a bounty of new, laboratory-proven medicinal plants and compounds. It is quite difficult to test, isolate, and elucidate the structure and mechanism of compounds from the plethora of new medicinal plant uses described each year with limited laboratory time and resources and the high cost of clinical trials of new drug candidates. Methods A new quantitative theoretical framework of mathematical formulas called "relational efficacy" is proposed that should narrow down this search for new plant-derived medicines based on the hypothesis that closely related plants used to treat closely related diseases in distantly related cultures have a higher probability of being effective because they are more likely to be independent discoveries of similar plant compounds and disease mechanisms. A prerequisite to this hypothesis, the idea that empirical testing in traditional medicine will lead to choosing similar medicinal plants and therefore the medicinal flora of two distant cultures will prove to be more similar than their general flora, is tested using resampling statistics on cross-cultural field data of the plants used by the Malinké of Mali and the Asháninka of Peru to treat the diseases malaria, African sleeping sickness, Chagas' disease, leishmaniasis, diabetes, eczema, asthma, and uterine fibroids. Results In this case, the similarity of the medicinal floras is found to be significantly greater than the similarity of the general floras, but only when the diseases in question are grouped into the categories of parasitic and autoimmune diseases. Conclusion If the central theoretical framework of this hypothesis is shown to be true, it will allow the synthesis of medicinal plant information

  6. Lineage-based analysis of the development of the central complex of the Drosophila brain.

    Science.gov (United States)

    Pereanu, Wayne; Younossi-Hartenstein, Amelia; Lovick, Jennifer; Spindler, Shana; Hartenstein, Volker

    2011-03-01

    Most neurons of the central complex belong to 10 secondary (larvally produced) lineages. In the late larva, undifferentiated axon tracts of these lineages form a primordium in which all of the compartments of the central complex can be recognized as discrete entities. Four posterior lineages (DPMm1, DPMpm1, DPMpm2, and CM4) generate the classes of small-field neurons that interconnect the protocerebral bridge, fan-shaped body, noduli, and ellipsoid body. Three lineages located in the anterior brain, DALv2, BAmv1, and DALcl2, form the large-field neurons of the ellipsoid body and fan-shaped body, respectively. These lineages provide an input channel from the optic tubercle and connect the central complex with adjacent anterior brain compartments. Three lineages in the posterior cortex, CM3, CP2, and DPMpl2, connect the posterior brain neuropil with specific layers of the fan-shaped body. Even though all of the compartments of the central complex are prefigured in the late larval brain by the axon tracts of the above-mentioned lineages, the neuropil differentiates during the first 2 days of the pupal period when terminal branches and synapses of secondary neurons are formed. During this phase the initially straight horizontal layers of the central complex bend in the frontal plane, which produces the characteristic shape of the fan-shaped and ellipsoid body. Our analysis provides a comprehensive picture of the lineages that form the central complex, and will facilitate future studies that address the structure or function of the central complex at the single cell level. PMID:21246549

  7. Deep sounding TEM investigation method based on a modified fixed central-loop system

    Science.gov (United States)

    Xue, Guo-qiang; Bai, Chao-ying; Yan, Shu; Greenhalgh, Stewart; Li, Mei-fang; Zhou, Nan-nan

    2012-01-01

    The central-loop TEM technology has been widely used in mineral exploration, engineering and environmental investigations and assorted geologic studies. For easy and efficient working conditions, a square (or rectangular) loop is generally employed instead of a circular one. Any position within the inner one ninth of the central part of the loop is often designated as the central survey location (within which the field is assumed to be uniform), and referred to as a modified central-loop configuration. However, the deduced field parameters at such non-central positions when calculated by a central-loop formula result in decreased accuracy and possibly erroneous interpretation. A large-fixed loop offers the advantage of being able to determine the induced potential at any point inside or outside the loop. In this study we provide the formula for the large-fixed loop and receiver positions within the modified central-loop system and solve the problem. Specifically, we compute the electromagnetic response of any field point by using an electric dipole integration method. The full time-domain apparent resistivity values are then extracted by using an iterative method. Both theoretical modeling and real data examples indicate that such a configuration not only improves the accuracy for the TEM survey, but also enlarges the exploration depth, due to a large loop used in the deployment. The method is used for locating the water enriched areas in coal mines in Yangquan region of Shanxi province and in Bin County of Shaanxi province, China. The interpreted results are tested by later drilling, which confirmed our combined method to be a reliable and efficient method for deep sounding.

  8. A quantitative synthesis of the medicinal ethnobotany of the Malinké of Mali and the Asháninka of Peru, with a new theoretical framework

    Directory of Open Access Journals (Sweden)

    Bletter Nathaniel

    2007-12-01

    Full Text Available Abstract Background Although ethnomedically and taxonomically guided searches for new medicinal plants can improve the percentage of plants found containing active compounds when compared to random sampling, ethnobotany has fulfilled little of its promise in the last few decades to deliver a bounty of new, laboratory-proven medicinal plants and compounds. It is quite difficult to test, isolate, and elucidate the structure and mechanism of compounds from the plethora of new medicinal plant uses described each year with limited laboratory time and resources and the high cost of clinical trials of new drug candidates. Methods A new quantitative theoretical framework of mathematical formulas called "relational efficacy" is proposed that should narrow down this search for new plant-derived medicines based on the hypothesis that closely related plants used to treat closely related diseases in distantly related cultures have a higher probability of being effective because they are more likely to be independent discoveries of similar plant compounds and disease mechanisms. A prerequisite to this hypothesis, the idea that empirical testing in traditional medicine will lead to choosing similar medicinal plants and therefore the medicinal flora of two distant cultures will prove to be more similar than their general flora, is tested using resampling statistics on cross-cultural field data of the plants used by the Malinké of Mali and the Asháninka of Peru to treat the diseases malaria, African sleeping sickness, Chagas' disease, leishmaniasis, diabetes, eczema, asthma, and uterine fibroids. Results In this case, the similarity of the medicinal floras is found to be significantly greater than the similarity of the general floras, but only when the diseases in question are grouped into the categories of parasitic and autoimmune diseases. Conclusion If the central theoretical framework of this hypothesis is shown to be true, it will allow the synthesis of

  9. Memory and Working-with-Memory: A Component Process Model Based on Modules and Central Systems.

    Science.gov (United States)

    Moscovitch, M

    1992-01-01

    Abstract A neuropsychological model of memory is proposed that incorporates Fodor's (1983) idea of modules and central systems. The model has four essential components: (1) a non-frontal neocortical component that consists of perceptual (and perhaps interpretative semantic) modules that mediate performance on item-specific, implicit tests of memory, (2) a modular medial temporal/hippocampal component that mediates encoding, storage, and retrieval on explicit, episodic tests of memory that are associative/cue dependent, (3) a central system, frontal-lobe component that mediates performance on explicit tests that are strategic and on procedural tests that are rule-bound, and (4) a basal ganglia component that mediates performance on sensorimotor, procedural tests of memory. The usefulness of the modular/central system construct is explored and evidence from studies of normal, amnesic, agnosic, and demented people is provided to support the model. PMID:23964882

  10. Investisseurs versus paysans locaux : vers quelle agriculture irriguée au Mali ? Investors vs. local farmers: the future of irrigated agriculture in Mali. The example of the sugar sector

    Directory of Open Access Journals (Sweden)

    Amandine Adamczewski

    2011-10-01

    Full Text Available Le phénomène d’appropriation foncière à grande échelle touche, depuis plusieurs années, le continent africain. Soucieux de moderniser leur agriculture et de trouver des capitaux pour la développer, de nombreux États ont fait le choix de recourir à des investisseurs privés étrangers. Au Mali, dans le plus grand périmètre irrigué d’Afrique de l’Ouest, des milliers d’hectares sont maintenant attribués à des investisseurs. Le Projet sucrier de Markala (PSM, issu d’un partenariat entre le gouvernement malien et un investisseur privé sud-africain, porte sur près de 40 000 hectares. Fort de nombreuses expériences en Zambie et en Afrique du Sud, premier producteur de sucre du continent, l’investisseur souhaite reproduire au Mali son modèle industriel : culture de canne à sucre en régie et avec des paysans sous contrat. Le projet entre en concurrence directe avec des paysans maliens pour l’accès à la terre et à l’eau. Il a en effet deux répercussions majeures : l’exclusion des paysans des parcelles et une compétition pour l’accès à l’eau. À partir des réactions paysannes, l’article analyse la cohabitation entre exploitations agricoles familiales et nouveaux investisseurs, ainsi que les disparités locales qui se créent. Alors que le gouvernement souhaite développer l’agrobusiness, l’accompagnement et la régulation des investissements sont peu effectifs.For several years, the African continent has been affected by large-scale land appropriations. Many governments have resorted to foreign private investors to modernise their agricultural sectors and raise capital for agricultural development. In Mali, which has the largest irrigated sector in Western Africa, investors now own thousands of hectares. The Markala Sugar Project (MSP, a partnership between the government and a private South African investor, covers some 40,000 hectares. Following initiatives in Zambia and South Africa (the

  11. Nature and evolution of Neoproterozoic ocean-continent transition: Evidence from the passive margin of the West African craton in NE Mali

    Science.gov (United States)

    Renaud, Caby

    2014-03-01

    The Timétrine massif exposed west of the Pan-African suture zone in northeastern Mali belongs to the passive margin of the West African craton facing to the east intra-oceanic arc assemblages and 730 Ma old pre-collisional calc-alkaline plutons. The Timétrine lithologic succession includes from the base to the top Mesoproterozoic cratonic to passive margin formations overlain by deep-sea Fe-Mg schists. Submarine metabasalts and two ultramafic massifs of serpentinized mantle peridotites are inserted as olistoliths towards the top whereas turbidites of continental origin represent the younger unit. Field and petrological data have revealed a distinct metasedimentary sequence attached to the serpentinized peridotites. It essentially consists of impure carbonates, Fe jaspers and polymictic breccias containing altered blocks of mantle peridotites, most rocks being enriched in detrital chromite. This association is interpreted as reworked chemical and detrital sediments derived from the alteration of mafic-ultramafic rocks. It is argued that mantle exhumation above sea floor took place during the Neoproterozoic rifting and crustal thinning period under possible tropical conditions, as suggested by the large volume of silicified serpentinites. In spite of greenschist facies metamorphic overprint characterized by widespread Fe-rich blue amphiboles that are not diagnostic of high-pressure conditions, it is possible to reconstruct a former ocean-continent transition similar to that evidenced for the Mesozoic period, followed by the deposition of syn-to post rift terrigeneous turbidites roughly coeval with ocean spreading some time before 800 Ma. It is concluded that the serpentinite massifs were tectonically emplaced first in an extensional setting, then incorporated within deep-sea sediments as olistoliths and finally transported westward during late Neoproterozoic collisional tectonics onto the West African craton.

  12. Heaven on Earth? The development of tourism in the Dogon Country and the Hombori Mountains (Mali Le Paradis sur Terre ? Le développement du tourisme au Pays Dogon et dans les Monts Hombori (Mali

    Directory of Open Access Journals (Sweden)

    Olivier Walther

    2008-10-01

    Full Text Available Cet article étudie le développement touristique inégal de deux destinations touristiques du Mali: le Pays Dogon, un must du marché touristique ouest-africain, et les Monts Hombori, considérés comme un « paradis sur Terre » en raison de leur exceptionnelle biodiversité. En s’appuyant sur les travaux de Butler (1980, nos travaux suggèrent que ces lieux touristiques se situent à des stades très différents de leur cycle de vie touristique. Au Pays Dogon, l’intérêt constant manifesté par les anthropologues depuis les années 1930 a conduit au classement du site au Patrimoine de l’Humanité. Rien de tel à Hombori, où les amateurs de tourisme de montagne contemporains peuvent être considérés comme les pionniers de cette destination.This paper studies the unequal development of two tourist destinations in Mali: Dogon Country, a well-established tourist market area, and the Hombori Mountains, considered as a kind of “heaven on earth” due to their preserved biological biodiversity. Building on Butler’s destination life cycle model (1980, our research suggests Dogon Country benefits from a considerable, long-term advantage in terms of image, which has led to its inclusion within UNESCO’s World Heritage List. The situation is totally different in the Hombori Mountains where current mountain tourists can be considered as the trailblazers for this particular destination.

  13. Comparing the Gibraltar and Calabrian subduction zones (central western Mediterranean) based on seismic tomography

    Science.gov (United States)

    Argnani, Andrea; Battista Cimini, Giovanni; Frugoni, Francesco; Monna, Stephen; Montuori, Caterina

    2016-04-01

    The Central Western Mediterranean (CWM) was shaped by a complex tectonic and geodynamic evolution. Deep seismicity and tomographic studies point to the existence, under the Alboran and Tyrrhenian Seas, of lithospheric slabs extending down to the bottom of the mantle transition zone, at 660 km depth. Two narrow arcs correspond to the two slabs, the Gibraltar and Calabrian Arcs (e.g., Monna et al., 2013; Montuori et al., 2007). Similarities in the tectonic and mantle structure of the two areas have been explained by a common subduction and roll-back mechanism for the opening of the CWM, in which the two arcs are symmetrical end products. In spite of this unifying model, a wide amount of literature from different disciplines shows that many aspects of the two areas are still controversial. We present a new 3-D tomographic model at mantle scale for the Calabrian Arc and compare it with a recently published 3-D tomographic model for the Gibraltar Arc by Monna et al (2013). The two models are based on non-linear inversion of teleseismic phase arrivals, and have scale and parametrization that allow for a direct comparison. Unlike previous studies the tomographic models here presented include Ocean Bottom Seismometer broadband data, which improved the resolution of the mantle structures in the marine areas surrounding the arcs. We focus on key features of the two models that constrain reconstructions of the geodynamic evolution of the CWM (e.g., Monna et al., 2015). At Tortonian time the opening of the Tyrrhenian basin was in its initial stage, and the Calabrian arc formed subsequently; on the contrary, the Gibraltar arc was almost completely defined. We hypothesize that the complexity of the continental margin approaching the subduction zone played a key role during the final stages of the arc formation. References Monna, S., G. B. Cimini, C. Montuori, L. Matias, W. H. Geissler, and P. Favali (2013), New insights from seismic tomography on the complex geodynamic evolution

  14. Geodiversity of the Umbria region (central Italy): a GIS-based quantitative index

    Science.gov (United States)

    Melelli, Laura; Pica, Alessia; Del Monte, Maurizio

    2014-05-01

    The measure of natural range related to geological bedrock, landforms and geomorphological processes is the necessary starting point to geodiversity evaluation. Geodiversity plays a strategic role in landscape management. Whereas geotourism and geosites are identified as a driving power for the scientific and economic promotion of an area, the geodiversity knowledge is required for a complete and accurate research. For example, high values of this abiotic parameter identify and support the foundation of geoparks. According to this perspective, the geodiversity is the unifying factor for these areas of interest. While a subjective and qualitative approach may be adequate for geosites definition, identification and cultural promotion, the geodiversity concept needs a different evaluation method. A quantitative procedure allows achieving an objective and repeatable process exportable in different geographic units. Geographical Information Systems and spatial analysis techniques are the base to quantitative evaluation involving topographic, geological and geomorphological data. Therefore, the assessment of a numerical index derived from the overlay of spatial parameters can be conveniently computed in GIS environment. In this study, a geodiversity index is proposed where geological, geomorphological and landcover factors deriving mainly from maps and field survey; topographic ones are employed from DEM and remote sensed data. Each abiotic parameter is modelled in a grid format; focal functions do provide neighbourhood analysis and computing variety statistics. A particular extent is dedicated to topographic information and terrain roughness, that are strictly related to efficiency of geomorphological processes and generally corresponding to the abiotic components variability. The study area is located in central Italy and is characterized by a well known natural heritage. Thirty-seven geosites are detected in the Umbria region, where seven regional and one natural

  15. Centralized optical-frequency-comb-based RF carrier generator for DWDM fiber-wireless access systems

    DEFF Research Database (Denmark)

    Pang, Xiaodan; Beltran, Marta; Sanchez, Jose;

    2014-01-01

    In this paper, we report on a gigabit capacity fiber-wireless system that enables smooth integration between high-speed wireless networks and dense wavelength-division-multiplexing (DWDM) access networks. By employing a centralized optical frequency comb, both the wireline and the wireless services...

  16. Constructing Market-based Economies in Central Asia: A Natural Experiment?

    Directory of Open Access Journals (Sweden)

    Pomfret, Richard

    2010-12-01

    Full Text Available This paper reviews the experience of the five Central Asian countries in the two decades since independence. In the 1990s the five countries looked like a natural experiment. They had similar initial conditions, but different transition strategies. Today that does not appear to have been a useful research agenda, which raises some broader questions for comparative economic studies.

  17. Sensor-based mapping of soil quality on degraded claypan landscapes of the central United States

    Science.gov (United States)

    Claypan soils (Epiaqualfs) in the central USA have experienced severe erosion as a result of tillage practices of the late 1800s and 1900s. Because of the site-specific nature of erosion processes within claypan fields, research is needed to achieve cost-effective sensing and mapping of soil and lan...

  18. L’introuvable capitale du Mali. La question de la capitale dans l’historiographie du royaume médiéval du Mali The capital that cannot be found: The question of the capital in the historiography of the medieval kingdom of Mali

    Directory of Open Access Journals (Sweden)

    Hadrien Collet

    2013-05-01

    Full Text Available Parmi les nombreuses hypothèses portant sur la capitale du Mali à son apogée (xiiie-début xve siècle, celle de Niani, apparue sous la plume des « historiens coloniaux », a connu la plus belle fortune. Construite par l’histoire coloniale, puis partiellement déconstruite à partir des années 1970, l’hypothèse de Niani, bien que porteuse d’une façon de faire de l’histoire aujourd’hui révolue, continue d’avoir ses partisans. Apparue en 1923, elle traverse l’époque coloniale et celle des indépendances des années 1960 avant de se retrouver confrontée à la méthode critique de l’histoire académique et de l’archéologie. Cette étude propose donc d’appréhender l’historiographie spécifique à Niani, qui reflète les évolutions de l’écriture de l’histoire ancienne du Soudan, et de faire le point sur l’état des recherches actuelles sur la question de la capitale du Mali.In the writings of “colonialist historians”, the hypothesis of Niani was certainly the main one formulated about the capital of medieval Mali at its height, from the 13th till the middle of the 15th century. This hypothesis, produced by colonial history in 1923 but partially deconstructed since the 1970s, still has strong support despite its outdated approach to writing history. It was advanced during the colonial era and the period of independence (the 1960s, before being subjected to a critique from academic history and archaeology. The historiography of Niani is presented as a reflection of trends in the writing of the history of the ancient Sudan, and current research on Mali’s capital is examined.

  19. Distribution of freshwater snails in the river Niger basin in Mali with special reference to the intermediate hosts of schistosomes

    DEFF Research Database (Denmark)

    Madsen, Henry; Coulibaly, Godefroy; Furu, Peter

    1987-01-01

    densities appeared to be associated with human water contact activities, which apparently create favourable biotopes for the snails. This is probably due to an alteration of the vegetation and an increase of the trophic status of the site by contamination with food remnants and other debris. The larger...... irrigation canals or lakes in these schemes play an important role in the transmission of human schistosomes and transmission appears to be very focal in these habitats. Infected snails are almost exclusively found in well-defined human water contact sites (WCS). Local infection rates with schistosomes were......Snail surveys were carried out in various parts of Mali. All areas surveyed are part of the Niger basin being either affluents or irrigation schemes fed by this river. The snail species present varied greatly between areas. The following potential hosts of schistosomes were recorded: Biomphalaria...

  20. Antimalarial activity of extracts and alkaloids isolated from six plants used in traditional medicine in Mali and Sao Tome.

    Science.gov (United States)

    Ancolio, C; Azas, N; Mahiou, V; Ollivier, E; Di Giorgio, C; Keita, A; Timon-David, P; Balansard, G

    2002-11-01

    Methanol and chloroform extracts were prepared from various parts of four plants collected in Mali: Guiera senegalensis (Gmel.) Combretaceae, Feretia apodanthera (Del.) Rubiaceae, Combretum micranthum (Don.) Combretaceae, Securidaca longepedunculata (Fres.) Polygalaceae and two plants -collected in Sao Tome: Pycnanthus angolensis (Welw.) Myristicaceae and Morinda citrifolia (Benth.) Rubiaceae were assessed for their in vitro antimalarial activity and their cytotoxic effects on human monocytes (THP1 cells) by flow cytometry. The methanol extract of leaves of Feretia apodanthera and the chloroform extract of roots of Guiera senegalensis exhibited a pronounced antimalarial activity. Two alkaloids isolated from the active extract of Guiera senegalensis, harman and tetrahydroharman, showed antimalarial activity (IC(50) lower than 4 microg/mL) and displayed low toxicity against THP1. Moreover, the decrease of THP1 cells in S phase of the cell cycle, after treatment with harman and tetrahydroharman, was probably due to an inhibition of total protein synthesis. PMID:12410545

  1. On-farm yield potential of local seed watermelon landraces under heat- and drought-prone conditions in Mali

    DEFF Research Database (Denmark)

    Nantoume, Aminata Dolo; Christiansen, Jørgen Lindskrog; Andersen, Sven Bode;

    2012-01-01

    On-farm yield experiments were carried out in the Tombouctou region of Mali in 2009/10 under heat- and drought-prone desert conditions with three local landraces of seed-type watermelons. The landraces, named Fombou, Kaneye and Musa Musa by the farmers, exhibited distinct characteristics for fruit...... morphology, but in particular for seed traits. On average, the three landraces produced a fruit yield of 11·6 t/ha and an estimated seed yield of 364 kg/ha, with no significant differences among landraces. Kaneye showed the highest stability of fruit number/ha in different field environments, suggesting this...... landrace is the best among the three for a poor growing environment, whereas Fombou and especially Musa Musa responded positively to more favourable environments. Seed weight revealed a different trend, with Fombou as the most responsive to favourable conditions, while Kaneye and Musa Musa were less...

  2. Whole Genome Sequencing of Mycobacterium africanum Strains from Mali Provides Insights into the Mechanisms of Geographic Restriction

    Science.gov (United States)

    Maiga, Mamoudou; Abeel, Thomas; Shea, Terrance; Desjardins, Christopher A.; Diarra, Bassirou; Baya, Bocar; Sanogo, Moumine; Diallo, Souleymane; Earl, Ashlee M.; Bishai, William R.

    2016-01-01

    Background Mycobacterium africanum, made up of lineages 5 and 6 within the Mycobacterium tuberculosis complex (MTC), causes up to half of all tuberculosis cases in West Africa, but is rarely found outside of this region. The reasons for this geographical restriction remain unknown. Possible reasons include a geographically restricted animal reservoir, a unique preference for hosts of West African ethnicity, and an inability to compete with other lineages outside of West Africa. These latter two hypotheses could be caused by loss of fitness or altered interactions with the host immune system. Methodology/Principal Findings We sequenced 92 MTC clinical isolates from Mali, including two lineage 5 and 24 lineage 6 strains. Our genome sequencing assembly, alignment, phylogeny and average nucleotide identity analyses enabled us to identify features that typify lineages 5 and 6 and made clear that these lineages do not constitute a distinct species within the MTC. We found that in Mali, lineage 6 and lineage 4 strains have similar levels of diversity and evolve drug resistance through similar mechanisms. In the process, we identified a putative novel streptomycin resistance mutation. In addition, we found evidence of person-to-person transmission of lineage 6 isolates and showed that lineage 6 is not enriched for mutations in virulence-associated genes. Conclusions This is the largest collection of lineage 5 and 6 whole genome sequences to date, and our assembly and alignment data provide valuable insights into what distinguishes these lineages from other MTC lineages. Lineages 5 and 6 do not appear to be geographically restricted due to an inability to transmit between West African hosts or to an elevated number of mutations in virulence-associated genes. However, lineage-specific mutations, such as mutations in cell wall structure, secretion systems and cofactor biosynthesis, provide alternative mechanisms that may lead to host specificity. PMID:26751217

  3. A Review of a Successful Unsubsidized Market-Based Rural Solar Development Initiative in Laikipia District, Central Kenya

    OpenAIRE

    O. Wambuguh

    2013-01-01

    The development of renewable energy technologies (RETs) in many areas far from grid-based electricity have primarily involved solar photovoltaics (SPVs) which tap solar radiation to provide heat, light, hot water, electricity, and cooling for homes, businesses, and industry. A study on RETs took place in the Wiyumiririe Location of Laikipia District (north-central Kenya), a rich agricultural region. To explore this solar initiative in such a remote part of the country, a purposive randomized ...

  4. Integration of vision and central pattern generator based locomotion for path planning of a non-holonomic crawling humanoid robot

    OpenAIRE

    Gay, Sébastien; Dégallier Rochat, Sarah; Ijspeert, Auke; Santos-Victor, José

    2010-01-01

    In this paper we present our work on integrating a locomotion controller based on central pattern generator (CPG) and a motion planning algorithm using artificial potential fields for a non-holonomic crawling humanoid robot, the iCub. We also integrated a vision tracker and an inverse kinematics solver to perform reaching tasks. We study the influence of the various parameters of the potential field equations on the performance of the system and prove the efficiency of our framework by testin...

  5. Aetiologies of Central Nervous System infections in adults in Kathmandu, Nepal: A prospective hospital-based study

    OpenAIRE

    Giri, Abhishek; Arjyal, Amit; Koirala, Samir; Karkey, Abhilasha; Dongol, Sabina; Thapa, Sudeep Dhoj; Shilpakar, Olita; Shrestha, Rishav; Van Tan, Le; Thi Thuy Chinh, Bkrong Nguyen; Krishna K. C., Radheshyam; Pathak, Kamal Raj; Shakya, Mila; Farrar, Jeremy; Van Doorn, H. Rogier

    2013-01-01

    We conducted a prospective hospital based study from February 2009-April 2011 to identify the possible pathogens of central nervous system (CNS) infections in adults admitted to a tertiary referral hospital (Patan Hospital) in Kathmandu, Nepal. The pathogens of CNS infections were confirmed in cerebrospinal fluid (CSF) using molecular diagnostics, culture (bacteria) and serology. 87 patients were recruited for the study and the etiological diagnosis was established in 38% (n = 33). The bacter...

  6. Mineral Deposit Data for Epigenetic Base- and Precious-metal and Uranium-thorium Deposits in South-central and Southwestern Montana and Southern and Central Idaho

    Science.gov (United States)

    Klein, T.L.

    2004-01-01

    Metal deposits spatially associated with the Cretaceous Boulder and Idaho batholiths of southwestern Montana and southern and central Idaho have been exploited since the early 1860s. Au was first discovered in placer deposits; exploitation of vein deposits in bedrock soon followed. In 1865, high-grade Ag vein deposits were discovered and remained economically important until the 1890s. Early high-grade deposits of Au, Ag and Pb were found in the weathered portions of the veins systems. As mining progressed to deeper levels, Ag and Pb grades diminished. Exploration for and development of these vein deposits in this area have continued until the present. A majority of these base- and precious-metal vein deposits are classified as polymetallic veins (PMV) and polymetallic carbonate-replacement (PMR) deposits in this compilation. Porphyry Cu and Mo, epithermal (Au, Ag, Hg and Sb), base- and precious-metal and W skarn, W vein, and U and Th vein deposits are also common in this area. The world-class Butte Cu porphyry and the Butte high-sulfidation Cu vein deposits are in this study area. PMV and PMR deposits are the most numerous in the region and constitute about 85% of the deposit records compiled. Several types of syngenetic/diagenetic sulfide mineral deposits in rocks of the Belt Supergroup or their equivalents are common in the region and they have been the source of a substantial metal production over the last century. These syngenetic deposits and their metamorphosed/structurally remobilized equivalents were not included in this database; therefore, deposits in the Idaho portion of the Coeur d'Alene district and the Idaho Cobalt belt, for example, have not been included because many of them are believed to be of this type.

  7. 3D VISION-BASED DIETARY INSPECTION FOR THE CENTRAL KITCHEN AUTOMATION

    OpenAIRE

    Yue-Min Jiang; Ho-Hsin Lee; Cheng-Chang Lien; Chun-Feng Tai; PiChun Chu; Ting-Wei Yang

    2014-01-01

    This paper proposes an intelligent and automatic dietary inspection system which can be applied to the dietary inspection for the application of central kitchen automation. The diet specifically designed for the patients are required with providing personalized diet such as low sodium intake or some necessary food. Hence, the proposed system can benefit the inspection process that is often performed manually. In the proposed system, firstly, the meal box can be detected and loc...

  8. Regulating the grid-based energies in Central and Eastern Europe: models, status, issues

    International Nuclear Information System (INIS)

    As the electricity, gas and heat industries of the economies in transition move towards more market-oriented frameworks, regulators are established to secure fair competition, protection of the customers and a minimum of public service. The paper describes the various models used or contemplated in the autumn of 2000 in central and eastern Europe and identifies fifteen issues, some falling under the competence of governments, others challenging the regulators, again others relating to international co-operation. (author)

  9. An InSAR-based survey of volcanic deformation in the central Andes

    OpenAIRE

    M. E. Pritchard; Simons, M.

    2004-01-01

    We extend an earlier interferometric synthetic aperture radar (InSAR) survey covering about 900 remote volcanos of the central Andes (14°–27°S) between the years 1992 and 2002. Our survey reveals broad (10s of km), roughly axisymmetric deformation at 4 volcanic centers: two stratovolcanoes are inflating (Uturuncu, Bolivia, and Hualca Hualca, Peru); another source of inflation on the border between Chile and Argentina is not obviously associated with a volcanic edifice (here called Lazufre); a...

  10. Identification keys on rattans (Calamus spp.) from Central Sulawesi based on anatomical structure of stems

    OpenAIRE

    ANDI TANRA TELLU

    2005-01-01

    This study was conducted to obtain information the anatomical characteristics of 20 rattan species from Central Sulawesi and to use it for anatomical identification of rattan species. The rattan comprised 16 Calamus species, three Daemonorops species and one Korthalsia species. For anatomical observation 10-15 mm pieces of the mature stem from shares of tip do not have frond were processed with polyethilene glycol 2000, cut at 18-32 µm and stained with a combination of acridin-cryzoidin red a...

  11. Tectonic structure of Central-Western Attica (Greece) based on geophysical invesigations - preliminary results.

    OpenAIRE

    Papadopoulos, T. D.; Goulty, N.; Voulgaris, N. S.; Alexopoulos, J. D.; Fountoulis, I.; Kambouris, P.; Karastathis, V.; Peirce, C.; S. Chailas; Kassaras, J.; Pirli, M.; Goumas, G.; Lagios, E.

    2007-01-01

    In an effort to investigate the deep geological structure in the broader area of central-western Attica, that suffered severe damage during the destructive Athens earthquake of September 7th, 1999, the Department of Geophysics-Geothermics of the Faculty of Geology and Geoenvironment of Athens University, in collaboration with the Geodynamic Institute of National Observatory of Athens and the Department of Geological Sciences of Durham University, carried out a combined geophysical survey. ...

  12. SensorBase.org - A Centralized Repository to Slog Sensor Network Data

    OpenAIRE

    Chang, Kevin; Yau, Nathan; Hansen, Mark; Estrin, D

    2006-01-01

    Various sensor networks use different data storage and management mechanisms. In particular, UCLA’s ESS2 mechanism forwards information from low powered 8-bit Mica2 motes to one or more low powered sinks that then push log files to a secure and centralized repository. While this data storage and management mechanism is straightforward to implement, publishing and sharing various data to various users has been a challenge. Users that need to parse the data often find it time consuming and erro...

  13. Teachers' professional development in a community: A study of the central actors, their networks and web-based learning

    Directory of Open Access Journals (Sweden)

    Jiri Lallimo

    2008-07-01

    Full Text Available The goal of this article was to study teachers' professional development related to web-based learning in the context of the teacher community. The object was to learn in what kind of networks teachers share the knowledge of web-based learning and what are the factors in the community that support or challenge teachers professional development of web-based learning. The findings of the study revealed that there are teachers who are especially active, called the central actors in this study, in the teacher community who collaborate and share knowledge of web-based learning. These central actors share both technical and pedagogical knowledge of web-based learning in networks that include both internal and external relations in the community and involve people, artefacts and a variety of media. Furthermore, the central actors appear to bridge different fields of teaching expertise in their community.According to the central actors' experiences the important factors that support teachers' professional development of web-based learning in the community are; the possibility to learn from colleagues and from everyday working practices, an emotionally safe atmosphere, the leader's personal support and community-level commitment. Also, the flexibility in work planning, challenging pupils, shared lessons with colleagues, training events in an authentic work environment and colleagues' professionalism are considered meaningful for professional development. As challenges, the knowledge sharing of web-based learning in the community needs mutual interests, transactive memory, time and facilities, peer support, a safe atmosphere and meaningful pedagogical practices.On the basis of the findings of the study it is suggested that by intensive collaboration related to web-based learning it may be possible to break the boundaries of individual teachership and create such sociocultural activities which support collaborative professional development in the teacher

  14. ''Yeelen Kura'', the new light. 1. the Acces programs in Mali. 2 the Acces approach; ''Yeelen Kura'', nouvelle lumiere. 1. les programmes Acces au Mali. 2. l'approche Acces

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-12-01

    In order to help the developing countries, EDF began in 2001 the Acces program. This program aims at installing in rural area, rentable projects of decentralized electrification. This document presents the economic aspects of the first installation, in Mali. (A.L.B.)

  15. The design of future central receiver power plants based on lessons learned from the Solar One Pilot Plant

    Science.gov (United States)

    Kolb, G. J.

    The 10-MW(sub e) Solar One Pilot Plant was the world's largest solar central receiver power plant. During its power production years it delivered over 37,000 MWhrs (net) to the utility grid. In this type of electric power generating plant, large sun-tracking mirrors called heliostats reflect and concentrate sunlight onto a receiver mounted on top of a tower. The receiver transforms the solar energy into thermal energy that heats water, turning it into superheated steam that drives a turbine to generate electricity. The Solar One Pilot Plant successfully demonstrated the feasibility of generating electricity with a solar central receiver power plant. During the initial 2 years the plant was tested and 4 years the plant was operated as a power plant, a great deal of data was collected relating to the efficiency and reliability of the plant's various systems. This paper summarizes these statistics and compares them to goals developed by the U.S. Department of Energy. Based on this comparison, improvements in the design and operation of future central receiver plants are recommended. Research at Sandia National Laboratories and the U.S. utility industry suggests that the next generation of central receiver power plants will use a molten salt heat transfer fluid rather than water/steam. Sandia has recently completed the development of the hardware needed in a molten salt power plant. Use of this new technology is expected to solve many of the performance problems encountered at Solar One. Projections for the energy costs from these future central receiver plants are also presented. For reference, these projections are compared to the current energy costs from the SEGS parabolic trough plants now operating in Southern California.

  16. Performance of grid-tied PV facilities based on real data in Spain: Central inverter versus string system

    International Nuclear Information System (INIS)

    Highlights: • The operation of two grid-tied PV facilities over a two-year period is presented. • The central inverter system is compared to the string inverter system. • A procedure based on a small number of easily obtained parameters is used. • The string inverter outperforms the central inverter. • Conclusions of use to maintenance firms and operational facilities are obtained. - Abstract: Two complete years of operation of two grid-tied PV facilities is presented. Energetic and economic performance of both installations has been compared. Located in the same place, the installation of these facilities followed the same construction criteria – PV panels, panel support system and wiring – and the facilities are exposed to the same atmospheric temperature and solar radiation. They differ with regard to their inverter topology used: one facility uses a central inverter and the other a string inverter configuration. The performance of the facilities has been determined using a procedure based on a small number of easily obtained parameters and the knowledge of the analyzed system and its operation mode. Electrical losses have been calculated for both systems and a complete comparison between them has been carried out. The results have shown better performance for distributed system in economic and energetic terms

  17. The Discriminative validity of "nociceptive," "peripheral neuropathic," and "central sensitization" as mechanisms-based classifications of musculoskeletal pain.

    LENUS (Irish Health Repository)

    Smart, Keith M

    2012-02-01

    OBJECTIVES: Empirical evidence of discriminative validity is required to justify the use of mechanisms-based classifications of musculoskeletal pain in clinical practice. The purpose of this study was to evaluate the discriminative validity of mechanisms-based classifications of pain by identifying discriminatory clusters of clinical criteria predictive of "nociceptive," "peripheral neuropathic," and "central sensitization" pain in patients with low back (+\\/- leg) pain disorders. METHODS: This study was a cross-sectional, between-patients design using the extreme-groups method. Four hundred sixty-four patients with low back (+\\/- leg) pain were assessed using a standardized assessment protocol. After each assessment, patients\\' pain was assigned a mechanisms-based classification. Clinicians then completed a clinical criteria checklist indicating the presence\\/absence of various clinical criteria. RESULTS: Multivariate analyses using binary logistic regression with Bayesian model averaging identified a discriminative cluster of 7, 3, and 4 symptoms and signs predictive of a dominance of "nociceptive," "peripheral neuropathic," and "central sensitization" pain, respectively. Each cluster was found to have high levels of classification accuracy (sensitivity, specificity, positive\\/negative predictive values, positive\\/negative likelihood ratios). DISCUSSION: By identifying a discriminatory cluster of symptoms and signs predictive of "nociceptive," "peripheral neuropathic," and "central" pain, this study provides some preliminary discriminative validity evidence for mechanisms-based classifications of musculoskeletal pain. Classification system validation requires the accumulation of validity evidence before their use in clinical practice can be recommended. Further studies are required to evaluate the construct and criterion validity of mechanisms-based classifications of musculoskeletal pain.

  18. Effect of trap color and orientation on the capture of Aphelinus mali (Hymenoptera: Aphelinidae), a parasitoid of woolly apple aphid (Hemiptera: Aphididae).

    Science.gov (United States)

    Beers, Elizabeth H

    2012-08-01

    The factors affecting trap capture of adult Aphelinus mali (Haldeman) (Hymenoptera: Aphelinidae) were studied in 2010-2011 in eastern Washington apple (Malus spp.) orchards infested with its host woolly apple aphid, Eriosoma lanigerum (Hausmann) (Hemiptera: Aphididae). The initial study of white sticky cards indicated that traps stapled to the trunk in a vertical orientation had the highest capture. A factorial experiment of three colors (clear, white, and yellow) by three orientations (trunk, scaffold, and hanging) indicated that yellow traps and traps on trunks caught higher numbers ofA. mali. For this reason, the recommended trap for this natural enemy is a yellow trap stapled to the trunk. Having a readily available and effective sampling method for this species may be helpful in implementing biological control programs and assessing the impact of different spray regimes. PMID:22928315

  19. Seasonality and shift in age-specific malaria prevalence and incidence in Binko and Carrière villages close to the lake in Selingué, Mali

    DEFF Research Database (Denmark)

    Touré, Mahamoudou; Sanogo, Daouda; Dembele, Soumaila;

    2016-01-01

    BACKGROUND: Malaria transmission in Mali is seasonal and peaks at the end of the rainy season in October. This study assessed the seasonal variations in the epidemiology of malaria among children under 10 years of age living in two villages in Selingué: Carrière, located along the Sankarani River...... but distant from the hydroelectric dam, and Binko, near irrigated rice fields, close to the dam. The aim of this study was to provide baseline data, seasonal pattern and age distribution of malaria incidence in two sites situated close to a lake in Selingué. METHODS: Geographically, Selingué area is located...... in the basin of Sakanrani and belongs to the district of Yanfolila in the third administrative region of Mali, Sikasso. Two cross-sectional surveys were conducted in October 2010 (end of transmission season) and in July 2011 (beginning of transmission season) to determine the point prevalence of asymptomatic...

  20. A review of research and literature related to the origin and identity of the cultivars Plavac mali, Zinfandel and Primitivo (Vitis vinifera L.

    Directory of Open Access Journals (Sweden)

    Nikola Mirošević

    2000-03-01

    Full Text Available The origin of Zinfandel, the important California wine cultivar, has been a question for several decades. Although Zinfandel has been linked to both Primitivo, grown in southern Italy, and to Plavac mali in Croatia, the puzzle of its origin has never been solved. Many scientists and writers have applied themselves to this question. Many hypotheses have been proposed and some erroneous ideas have been widely accepted. Much of the controversy will now be ended as a result of recent scientific research (Pejić and co-workers, 2000. Here we review the research and written documentation about Plavac mali, Zinfandel and Primitivo and their relationships and we present the results of recent research.

  1. Kamu mali yönetiminde iç denetim uygulaması ve iç denetim algısı

    OpenAIRE

    Gürkan, Nazmi Zarifi

    2010-01-01

    Bu çalışmanın amacı, ülkemizde uygulanmakta olan mali yönetim ve kontrol sitemi içerisindeki iç denetim faaliyetinin rolü, uygulanabilirliği ve mevcut sorunlara yönelik çözüm önerileri ortaya koymaktır. Bu çerçevede, Türkiye'de 5018 sayılı Kamu Mali Yönetimi ve Kontrol Kanunu ile uygulama alanı bulan iç denetim fonksiyonu, etkinliğini ve uygulama sorunlarına yönelik hususlar değerlendirmeye alınmaktadır. Çalışma dört bölümden oluşmaktadır. Birinci bölümde denetim kavramın tarihsel gelişimi ve...

  2. Turbine model for the Laguna Verde nucleo electric central based in the RELAP code

    International Nuclear Information System (INIS)

    The Nuclear Power stations as Laguna Verde occupy at the present time a place every time but important as non pollutant alternative, economic and trusty to generate electricity. It is for it that the Group of Nuclear Engineering of the Engineering Faculty (GrlNFI) of the National Autonomous University of Mexico (UNAM) it develops investigation projects applied to Nuclear Centrals. One of the projects in process is the development of a Classroom simulator, which it can configures to consent to diverse models of nuclear systems with training purposes in normal operation, or, to consent to specialized nuclear codes for the analysis of transitory events and have a severe accident. This work describes the development, implementation and it proves of a simplified model of the Main turbine to be integrated to the group of models of the Classroom simulator. It is part of the current effort of GrlNFI guided to obtain a representation of all the dynamic models necessary to simulate the Plant Balance of the Laguna Verde Central. It is included the development of the unfolding graphic which represent the modeling of the Main turbine, and of the control interface that allows the user to manipulate in simple way, direct and interactive this device during the training or the analysis. With this work it is wanted to contribute to the training of new technicians and to support the operation personnel of the Centrals. Also, the developed infrastructure is guided to contribute in the design and analysis of new Nuclear Power stations with the contribution of new computational tools for the visualization, simulation and process control. (Author)

  3. STRATEGIC PURCHASING IN A PROJECT- BASED COMPANY – TO CENTRALIZE OR DECENTRALIZE

    Directory of Open Access Journals (Sweden)

    Eva Donociková

    2014-03-01

    Full Text Available Organizations all lie on a spectrum, at one end of which are firms with complete centralization of purchasing, and at the other end are firms with complete decentralization. Most firms lie somewhere between the two extremes, and we have already mentioned the most common model that has certain decisions centralized (perhaps strategy design, selection of suppliers, purchasing of major capital equipment, training, co-ordination, communications, etc. and bulk of purchasing devolved to local buyers. There are many variations on the type of activities that are either centralized or decentralized. In the last 12 years purchasing has noticed two radical changes in the majority of facilities. First change was the reverse of supplier – customer relationships where the role of purchasers changed from persuading and begging the suppliers to ever deliver, preferably with minimum delay (for fixed prices, to standard purchase activities where the purchaser can choose from many suppliers and negotiate prices with vendors to achieve the best conditions for his buyer. The second change was the establishing of a modern IT system that made purchasing activities more effective, more automatic and transparent to a considerable extent. It is good to realize whether all changes have led to improvement or whether these changes have caused a stop or a slowdown of the project purchasing – whether it is possible or even necessary to take into account global as well as local suppliers or to combine them. This Case Study demonstrates how a project - managed organization could look like, where it is necessary to take into account customer´s wishes and benefit.

  4. Caribou, individual-based modeling and mega-industry in central West Greenland

    DEFF Research Database (Denmark)

    Raundrup, Katrine; Nymand, Josephine; Nabe-Nielsen, Jacob;

    Spatial distribution of caribou (Rangifer tarandus groenlandicus) in West Greenland is a result of both short and long term changes in the Arctic landscape. To understand present distribution 40 satellite collars were deployed on 40 female caribou in the Akia-Maniitsoq herd, central West Greenland...... distribution and caribou in a realistic but manipulable “virtual world” of an IBM it is possible to examine the plausible effects of different environmental impacts on the population dynamics of caribou in West Greenland. The simulations will include introduction of mega-industry, roads, and transmission lines...

  5. Structures based on semi-degradable biomaterials for neural regeneration in the central nervous system

    OpenAIRE

    Perez Garnes, Manuel

    2015-01-01

    Se pretende obtener un material semibiodegradable basado en ácido hialurónico químicamente enlazado a cadenas de polímeros acrílicos. Los hidrogeles de ácido hialurónico presentan en general buenas características para su utilización en regeneración del sistema nervioso central: es biodegradable, es un componente importante del tejido neural, sus propiedades mecánicas son semejantes a las del tejido cerebral, promueve la formación de nuevos capilares (angiogénesis), y limita la inflamación. C...

  6. Maximum principle and convergence of central schemes based on slope limiters

    KAUST Repository

    Mehmetoglu, Orhan

    2012-01-01

    A maximum principle and convergence of second order central schemes is proven for scalar conservation laws in dimension one. It is well known that to establish a maximum principle a nonlinear piecewise linear reconstruction is needed and a typical choice is the minmod limiter. Unfortunately, this implies that the scheme uses a first order reconstruction at local extrema. The novelty here is that we allow local nonlinear reconstructions which do not reduce to first order at local extrema and still prove maximum principle and convergence. © 2011 American Mathematical Society.

  7. Ocular biometry and central corneal thickness in children: a hospital-based study

    Directory of Open Access Journals (Sweden)

    Adem Gul

    2014-06-01

    Full Text Available Objetivo: Investigar a distribuição do comprimento axial, profundidade da câmara anterior, espessura do cristalino, profundidade da câmara vítrea e espessura corneal central em crianças em diferentes faixas etárias. Métodos: Foram estudados 364 olhos de 182 crianças entre 1 e 12 anos de idade. O comprimento axial, a profundidade da câmara anterior , a espessura do cristalino e a profundidade da câmara vítrea foram medidos por biometria ultrassônica. A espessura corneal central foi medida por paquimetria ultrassônica em todas as crianças. Resultados: A idade média foi de 6,54 ± 3,42 anos. O comprimento axial foi 20,95 mm no grupo de 1-2 anos de idade e 22,95 mm no grupo de 11-12 anos de idade. A espessura corneal central foi 556 µm no grupo de 1-2 anos de idade e 555 µm no grupo de 11-12 anos de idade. A profundidade da câmara anterior média e profundidade da câmara vítrea aumentou com a idade (3,06 mm a 3,44 mm de profundidade da câmara anterior, 13,75 mm a 15,99 mm de profundidade da câmara vítrea e da espessura do cristalino diminuiu com o aumento da idade (3,67 mm a 3,51 mm. Conclusões: Em nosso estudo, os valores do comprimento axial aumentou com a idade e atingiu os níveis adultos aos 9-10 anos de idade. A espessura do cristalino diminuiu gradualmente até os 12 anos de idade. As medições de espessura corneal central não seguiu um algoritmo linear.

  8. Irrigation Costs and Prices: An Institutional Economic Analysis of Pricing Strategies in the Office Du Niger and Small Pump-Irrigated Village Perimeters in Mali

    OpenAIRE

    Schrecongost, Alyse

    2005-01-01

    This paper explores the link between cost and price in two irrigation schemes in Mali - the Office du Niger (ON), a large-scale gravity irrigation authority, and a number of small pump-irrigated fields at village perimeters along the Niger River (Petits Perimetres d'Irrigation Villagois). I argue that the effectiveness of cost-recovery pricing strategies for improving the long-run financial sustainability of irrigation systems and advancing national development objectives is a function of dec...

  9. The key priority for Mali is ensuring that African forces are ready to take over when French troops leave the country

    OpenAIRE

    Gilmor, Jeff

    2013-01-01

    The French military operation in Mali has regained control of much of the country from Islamic militants. Jeff Gilmour provides an overview of the military situation and identifies a number of potential problems which must still be overcome. The crucial issue is likely to be ensuring that the African forces which take over from departing French troops are properly trained and avoid the logistical issues which have plagued other operations, such as the MONUSCO peace-keeping mission in the Demo...

  10. Contribution of Inland Valleys Intensification to Sustainable Rice/vegetable Value Chain Development in Benin and Mali: Constraints, opportunities and profitable cropping systems

    OpenAIRE

    Adetonah, Sounkoura; Coulibaly, Ousmane; Sessou, E.; Padonou, S.; Dembele, U.; Adekambli, S.

    2010-01-01

    Intensifying inland valley systems will require the promotion of high value commodity chain system involving rice and vegetable with increased productivity and low per unit cost of production and natural resources. The objective aim to identify the current production systems assesses their constraints and analyzes the profitability of best bet rice and vegetable cropping systems under different levels of input use and access to market. A total of 235 producers selected in Benin and Mali accor...

  11. Identification keys on rattans (Calamus spp. from Central Sulawesi based on anatomical structure of stems

    Directory of Open Access Journals (Sweden)

    ANDI TANRA TELLU

    2005-04-01

    Full Text Available This study was conducted to obtain information the anatomical characteristics of 20 rattan species from Central Sulawesi and to use it for anatomical identification of rattan species. The rattan comprised 16 Calamus species, three Daemonorops species and one Korthalsia species. For anatomical observation 10-15 mm pieces of the mature stem from shares of tip do not have frond were processed with polyethilene glycol 2000, cut at 18-32 µm and stained with a combination of acridin-cryzoidin red and astrablue. Cleared preparation were used to observe stegmata, and macerated material was used to measure the length of fibers and vessel elements. Anilin sulfate was used to confirm the existence of lignin. Anatomical characteristics used in identification were shape and will thickening of epidermal cells and the position stomata at epidermal; the arrangement of sub epidermal parenchyma; composition of vascular bundles and their distribution; the shape and arrangement of central ground parenchyma and the occurrence of fiber bundles. The research result indicated that the anatomical character can be compiled to a key identify the rattan at genus and species level.

  12. Sensor-Based Programming of Central Pattern Generators in Humanoid Robots

    Directory of Open Access Journals (Sweden)

    Hamed Shahbazi

    2013-04-01

    Full Text Available In the present article, a method for generating curvilinear bipedal walking patterns is proposed which is able to generate rhythmic and periodic trajectories for a Nao soccer player robot. To do so, a programmable central pattern generator was used which was inspired from locomotion structures in vertebrate animals. In this paper, the programmable central pattern generators were extended and new Equations were added to make a curvilinear pattern for walking Nao robots on a specified circular curve. In addition, some specific Equations were added to the model to control the arms and synchronize them with the movement of the feet. The model uses some sensory inputs to obtain some feedback from the movement and adjust it conforming to the potential perturbations. Input sensory values consist of accelerator values and foot pressure sensor values located on the bottom of each foot. Feedback values can adopt walking to some desired specifications and compensate the effects of some types of perturbations. The proposed model has many benefits including smooth walking patterns and modulation during walking. This model can be extended and used in the Nao soccer player both for the standard platform and the 3D soccer simulation leagues of Robocup SPL competitions to train different types of motions.

  13. Identifying the Critical Links in Road Transportation Networks: Centrality-based approach utilizing structural properties

    Energy Technology Data Exchange (ETDEWEB)

    Chinthavali, Supriya [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-04-01

    Surface transportation road networks share structural properties similar to other complex networks (e.g., social networks, information networks, biological networks, and so on). This research investigates the structural properties of road networks for any possible correlation with the traffic characteristics such as link flows those determined independently. Additionally, we define a criticality index for the links of the road network that identifies the relative importance in the network. We tested our hypotheses with two sample road networks. Results show that, correlation exists between the link flows and centrality measures of a link of the road (dual graph approach is followed) and the criticality index is found to be effective for one test network to identify the vulnerable nodes.

  14. A Novel Particle Swarm Optimization based Algorithm for the Optimal Centralized Wireless Access Network

    Directory of Open Access Journals (Sweden)

    Dac-Nhuong Le

    2013-01-01

    Full Text Available The wireless access networks design problem is formulated as a constrained optimization problem, where the goal is to find a network topology such that an objective function is optimized, subject to a set of constraints. The objective function may be the total cost, or some performance measure like utilization, call blocking or throughput. The constraints may be bounds on link capacities, cost elements, or some network performance measure. However, the optimization problem is too complex. In this paper, we propose a novel Particle Swarm Optimization (PSO algorithm to finding the total cost of connecting the BSs to the MSCs, and connecting the MSCs to the LE called by the optimal centralized wireless access network. Numerical results show that performance of our proposed algorithm is much better than previous studies.

  15. A new map of the vegetation of central European Russia based on high-resolution satellite data.

    Science.gov (United States)

    Ershov, D V; Gavrilyuk, E A; Karpukhina, D A; Kovganko, K A

    2015-01-01

    The scientific basis of and approaches to regional thematic mapping of vegetation based on high-resolution satellite data have been elaborated. A vegetation map of central European Russia has been compiled. The map includes 12 thematic classes, six of which pertain to forest ecosystems. The map has been compared to the data of the GFC project (University of Maryland, United States) and the official data of the Rosstat Federal Service of State Statistics (Russia). The new vegetation map is currently used in the information system of the remote monitoring of forest fires in Russia. PMID:26530069

  16. A positive correlation between atypical memory B cells and Plasmodium falciparum transmission intensity in cross-sectional studies in Peru and Mali.

    Directory of Open Access Journals (Sweden)

    Greta E Weiss

    Full Text Available BACKGROUND: Antibodies that protect against Plasmodium falciparum (Pf malaria are only acquired after years of repeated infections. The B cell biology that underlies this observation is poorly understood. We previously reported that "atypical" memory B cells are increased in children and adults exposed to intense Pf transmission in Mali, similar to what has been observed in individuals infected with HIV. In this study we examined B cell subsets of Pf -infected adults in Peru and Mali to determine if Pf transmission intensity correlates with atypical memory B cell expansion. METHODOLOGY/PRINCIPAL FINDINGS: In this cross-sectional study venous blood was collected from adults in areas of zero (U.S., n = 10, low (Peru, n = 18 and high (Mali, n = 12 Pf transmission. Adults in Peru and Mali were infected with Pf at the time of blood collection. Thawed lymphocytes were analyzed by flow cytometry to quantify B cell subsets, including atypical memory B cells, defined by the cell surface markers CD19(+ CD20(+ CD21(- CD27(- CD10(-. In Peru, the mean level of atypical memory B cells, as a percent of total B cells, was higher than U.S. adults (Peru mean: 5.4% [95% CI: 3.61-7.28]; U.S. mean: 1.4% [95% CI: 0.92-1.81]; p<0.0001 but lower than Malian adults (Mali mean 13.1% [95% CI: 10.68-15.57]; p = 0.0001. In Peru, individuals self-reporting ≥1 prior malaria episodes had a higher percentage of atypical memory B cells compared to those reporting no prior episodes (≥1 prior episodes mean: 6.6% [95% CI: 4.09-9.11]; no prior episodes mean: 3.1% [95% CI: 1.52-4.73]; p = 0.028. CONCLUSIONS/SIGNIFICANCE: Compared to Pf-naive controls, atypical memory B cells were increased in Peruvian adults exposed to low Pf transmission, and further increased in Malian adults exposed to intense Pf transmission. Understanding the origin, function and antigen specificity of atypical memory B cells in the context of Pf infection could contribute to our

  17. Aerosol optical depth over central north Asia based on MODIS-Aqua data

    Science.gov (United States)

    Avgousta Foutsi, Athina; Korras Carraca, Marios Bruno; Matsoukas, Christos; Biskos, George

    2016-04-01

    Atmospheric aerosols, both natural and anthropogenic, can affect the regional and global climate through their direct, indirect, and semi-direct effects on the radiative energy budget of the Earth-atmosphere system. To quantify these effects it is important to determine the aerosol load, and an effective way to do that is by measuring the aerosol optical depth (AOD). The central Asia region (mainly the Caspian and Aral sea basins), the arid and semi-arid regions of Western China as well as Siberia are of great interest due to the significant natural sources of mineral aerosols originating from local deserts and biomass burning from wildfires in boreal forests. What is of particular interest in the region is the phenomenal shrinking and desertification of the Aral Sea that drives an intense salt and dust transport from the exposed sea-bed to the surrounding regions with important implications in regional air quality. Anthropogenic particles are also observed due to fossil-fuel combustion occurring mainly at oil refineries in the Caspian Sea basin. Here we investigate the spatial and temporal variability of the AOD at 550 nm over central Asia, Siberia and western China, in the region located between 35° N - 65° N and 45° E - 110° E. For our analysis we use Level-3 daily MODIS - Aqua Dark Target - Deep Blue combined product, from the latest collection (006), available in a 1°×1° resolution (ca. 100 km × 100 km) over the period 2002-2014. Our results indicate a significant spatial variability of the aerosol load over the study region. The highest AODs are observed over the Aral Sea year-round, with extreme values reaching 2.1 during July. In the rest of our study region a clear seasonal cycle with highest AOD values (up to 1.2 over the Taklamakan Desert) during spring and summer is observed. The arid parts of central north Asia are characterized by larger aerosol loads during spring, lower but still high AOD in summer and much lower values in autumn and spring

  18. Nanofibrous scaffolds supporting optimal central nervous system regeneration: an evidence-based review

    Directory of Open Access Journals (Sweden)

    Kamudzandu M

    2015-12-01

    Full Text Available Munyaradzi Kamudzandu, Paul Roach, Rosemary A Fricker, Ying Yang Institute for Science and Technology in Medicine, School of Medicine, Keele University, Stoke-on-Trent, UK Abstract: Restoration of function following damage to the central nervous system (CNS is severely restricted by several factors. These include the hindrance of axonal regeneration imposed by glial scars resulting from inflammatory response to damage, and limited axonal outgrowth toward target tissue. Strategies for promoting CNS functional regeneration include the use of nanotechnology. Due to their structural similarity, synthetic nanofibers could play an important role in regeneration of CNS neural tissue toward restoration of function following injury. Two-dimensional nanofibrous scaffolds have been used to provide contact guidance for developing brain and spinal cord neurites, particularly from neurons cultured in vitro. Three-dimensional nanofibrous scaffolds have been used, both in vitro and in vivo, for creating cell adhesion permissive milieu, in addition to contact guidance or structural bridges for axons, to control reconnection in brain and spinal cord injury models. It is postulated that nanofibrous scaffolds made from biodegradable and biocompatible materials can become powerful structural bridges for both guiding the outgrowth of neurites and rebuilding glial circuitry over the “lesion gaps” resulting from injury in the CNS. Keywords: scaffold, nanofibrous scaffold, CNS, regeneration, alignment

  19. Soil erosion history in central Tanzania based on OSL dating of colluvial and alluvial hillslope deposits

    Science.gov (United States)

    Eriksson, M. G.; Olley, J. M.; Payton, R. W.

    2000-12-01

    The Irangi Hills in Kondoa District, central Tanzania, are severely degraded by sheet, rill and gully erosion. Using recently developed optically stimulated luminescence (OSL) dating techniques, and a detailed study of the hillslope stratigraphy and soils, we have determined the sequence of events that gave rise to this highly degraded landscape. Two major colluvial deposits have been identified on the slopes. The oldest colluvium gave OSL deposition dates of 14,700±1600, 14,200±1500 and 11,400±1300 years ago. These dates coincide with the climatic change from dry to wet conditions, which took place during the Late Pleistocene. It is possible that the erosion and deposition of the old colluvium occurred as a response to this change. This phase of erosion and deposition was followed by a long phase of stability and pedogenetic alteration of the old colluvium. A phase of accelerated soil erosion began not later than 900 years ago, as indicated by a dated alluvial fan, the presence of which indicates that some deeper gullies already existed on upper pediment slopes at that time. The second, more recent colluvial deposit gave OSL dates of 460±40, 590±70 and 660±50 years. A major period of gully formation and incision, with subsequent fan development, occurred sometime between 600 and 300 years ago. The recent phase of erosion (livestock husbandry and iron smelting practices in the Irangi Hills.

  20. Kinematics of the New Madrid seismic zone, central United States, based on stepover models

    Science.gov (United States)

    Pratt, Thomas L.

    2012-01-01

    Seismicity in the New Madrid seismic zone (NMSZ) of the central United States is generally attributed to a stepover structure in which the Reelfoot thrust fault transfers slip between parallel strike-slip faults. However, some arms of the seismic zone do not fit this simple model. Comparison of the NMSZ with an analog sandbox model of a restraining stepover structure explains all of the arms of seismicity as only part of the extensive pattern of faults that characterizes stepover structures. Computer models show that the stepover structure may form because differences in the trends of lower crustal shearing and inherited upper crustal faults make a step between en echelon fault segments the easiest path for slip in the upper crust. The models predict that the modern seismicity occurs only on a subset of the faults in the New Madrid stepover structure, that only the southern part of the stepover structure ruptured in the A.D. 1811–1812 earthquakes, and that the stepover formed because the trends of older faults are not the same as the current direction of shearing.

  1. Structure tensor based automated detection of macular edema and central serous retinopathy using optical coherence tomography images.

    Science.gov (United States)

    Hassan, Bilal; Raja, Gulistan; Hassan, Taimur; Usman Akram, M

    2016-04-01

    Macular edema (ME) and central serous retinopathy (CSR) are two macular diseases that affect the central vision of a person if they are left untreated. Optical coherence tomography (OCT) imaging is the latest eye examination technique that shows a cross-sectional region of the retinal layers and that can be used to detect many retinal disorders in an early stage. Many researchers have done clinical studies on ME and CSR and reported significant findings in macular OCT scans. However, this paper proposes an automated method for the classification of ME and CSR from OCT images using a support vector machine (SVM) classifier. Five distinct features (three based on the thickness profiles of the sub-retinal layers and two based on cyst fluids within the sub-retinal layers) are extracted from 30 labeled images (10 ME, 10 CSR, and 10 healthy), and SVM is trained on these. We applied our proposed algorithm on 90 time-domain OCT (TD-OCT) images (30 ME, 30 CSR, 30 healthy) of 73 patients. Our algorithm correctly classified 88 out of 90 subjects with accuracy, sensitivity, and specificity of 97.77%, 100%, and 93.33%, respectively. PMID:27140751

  2. Trends in health facility based maternal mortality in Central Region, Kenya: 2008-2012

    Science.gov (United States)

    Muchemi, Onesmus Maina; Gichogo, Agnes Wangechi; Mungai, Jane Githuku; Roka, Zeinab Gura

    2016-01-01

    Introduction WHO classifies Kenya as having a high maternal mortality. Regional data on maternal mortality trends is only available in selected areas. This study reviewed health facility maternal mortality trends, causes and distribution in Central Region of Kenya, 2008-2012. Methods We reviewed health records from July 2008 to June 2012. A maternal death was defined according to ICD-10 criterion. The variables reviewed included socio-demographic, obstetric characteristics, reasons for admission, causes of death and contributing factors. We estimated maternal mortality ratio for each year and overall for the four year period using a standard equation and used frequencies means/median and proportions for other descriptive variables. Results A total 421 deaths occurred among 344,191 live births; 335(80%) deaths were audited. Maternal mortality ratios were: 127/100,000 live births in 2008/09; 124/100,000 live births in 2009/2010; 129/100,000 live births in 2010/2011 and 111/100,000 live births in 2011/2012. Direct causes contributed majority of deaths (77%, n=234) including hemorrhage, infection and pre-eclampsia/eclampsia. Mean age was 30(±6) years; 147(71%) attended less than four antenatal visits and median gestation at birth was 38 weeks (IQR=9). One hundred ninety (59%) died within 24 hours after admission. There were 111(46%) caesarian births, 95(39%) skilled vaginal, 31(13%) unskilled 5(2%) vacuum deliveries and 1(<1%) destructive operation. Conclusion The region recorded an unsteady declining trend. Direct causes contributed to the majority deaths including hemorrhage, infection and pre-eclampsia/eclampsia. We recommend health education on individualized birth plan and mentorship on emergency obstetric care. Further studies are necessary to clarify and expand the findings of this study. PMID:27516824

  3. The central role of chloride in the metabolic acid-base changes in canine parvoviral enteritis.

    Science.gov (United States)

    Burchell, Richard K; Schoeman, Johan P; Leisewitz, Andrew L

    2014-04-01

    The acid-base disturbances in canine parvoviral (CPV) enteritis are not well described. In addition, the mechanisms causing these perturbations have not been fully elucidated. The purpose of the present study was to assess acid-base changes in puppies suffering from CPV enteritis, using a modified strong ion model (SIM). The hypothesis of the study was that severe acid-base disturbances would be present and that the SIM would provide insights into pathological mechanisms, which have not been fully appreciated by the Henderson-Hasselbalch model. The study analysed retrospective data, obtained from 42 puppies with confirmed CPV enteritis and 10 healthy control dogs. The CPV-enteritis group had been allocated a clinical score, to allow classification of the data according to clinical severity. The effects of changes in free water, chloride, l-lactate, albumin and phosphate were calculated, using a modification of the base excess algorithm. When the data were summated for each patient, and correlated to each individual component, the most important contributor to the metabolic acid-base changes, according to the SIM, was chloride (Penteritis are multifactorial and complex, with the SIM providing information in terms of the origin of these changes.

  4. ETHNO-CULTURAL CONTEXT OF THE FORMATION OF PROFESIONAL CULTURE OF FUTURE TEACHERS IN THE REPUBLIC OF MALI

    Directory of Open Access Journals (Sweden)

    Coulibaly O.

    2015-02-01

    Full Text Available The article focuses on the problem of formation of professional culture of the future teachers in the Republic of Mali, which is due to the current sociocultural configuration. In this regard, there is a need for preparing competent teachers,who are able not only to operate in a multiethnic environment, but also to combine national and international interests. Ethno-cultural values are the basis for the formation of personal and professional culture of the future teacher, they regulate teaching activities. The article defines the concepts of "ethno-cultural context", "ethno-cultural values" and describes the ethnic and linguistic composition of the Malian population. It examines in detail the nature, content and meaning of some important ethno-cultural pedagogical values that make up a solid foundation on which the life of Malian society is built. These values include "Sanankuya" or joking relationships,"Diatigiya" or hospitality, "The sense of family", "Responsible solidarity","Due respect to the elders, elderly and the disabled people," "Honor and dignity", "Patriotism and devotion" etc. The author concludes that the inclusion of ethno-cultural component in the educational process of preparing future teachers will help to introduce them to the national cultural values and therefore to therefore to maintain the cultural identity

  5. Quantifying Fertilizer Application Response Variability with VHR Satellite NDVI Time Series in a Rainfed Smallholder Cropping System of Mali

    Directory of Open Access Journals (Sweden)

    Xavier Blaes

    2016-06-01

    Full Text Available Soil fertility in smallholder farming areas is known to vary strongly on multiple scales. This study measures the sensitivity of the recorded satellite signal to on-farm soil fertility treatments applied to five crop types, and quantifies this fertilization effect with respect to within-field variation, between-field variation and field position in the catena. Plant growth was assessed in 5–6 plots per field in 48 fields located in the Sudano-Sahelian agro-ecological zone of southeastern Mali. A unique series of Very High Resolution (VHR satellite and Unmanned Aerial Vehicle (UAV images were used to calculate the Normalized Difference Vegetation Index (NDVI. In this experiment, for half of the fields at least 50% of the NDVI variance within a field was due to fertilization. Moreover, the sensitivity of NDVI to fertilizer application was crop-dependent and varied through the season, with optima at the end of August for peanut and cotton and early October for sorghum and maize. The influence of fertilizer on NDVI was comparatively small at the landscape scale (up to 35% of total variation, relative to the influence of other components of variation such as field management and catena position. The NDVI response could only partially be benchmarked against a fertilization reference within the field. We conclude that comparisons of the spatial and temporal responses of NDVI, with respect to fertilization and crop management, requires a stratification of soil catena-related crop growth conditions at the landscape scale.

  6. Antiplasmodial and GABA(A)-benzodiazepine receptor binding activities of five plants used in traditional medicine in Mali, West Africa.

    Science.gov (United States)

    Bah, Sekou; Jäger, Anna K; Adsersen, Anne; Diallo, Drissa; Paulsen, Berit Smestad

    2007-04-01

    Extracts of five medicinal plants: Boscia angustifolia, Cissus quadrangularis, Securidaca longipedunculata, Stylosanthes erecta and Trichilia emetica, used traditionally in Malian traditional medicine were screened for in vitro antiplasmodial activity and GABA(A)-benzodiazepine receptor binding activity. Four extracts showed significant antiplasmodial activities, with the dichloromethane extract of leaf of Securidaca longipedunculata being the most active (IC(50) of 7 microg/ml [95% CI: 5-9]). The dichloromethane extract of leaf of Trichilia emetica, in addition to its antiplasmodial activity (IC(50): 12 microg/ml [95% CI: 12-14]), exhibited a good binding activity to the GABA(A)-benzodiazepine receptor, while water and methanol extracts of the same plant did not show any activity. A strong GABA(A)-receptor complex binding activity was observed in the methanol extract of aerial part of Stylosanthes erecta. The results in this study justify some of the traditional indications of the plants investigated and may thus be candidates for Improved Traditional Medicines in Mali. PMID:17126508

  7. Economic and Social Sustainability Performance of Jatropha Projects: Results from Field Surveys in Mozambique, Tanzania and Mali

    Directory of Open Access Journals (Sweden)

    Henny Romijn

    2014-09-01

    Full Text Available This paper presents results from comprehensive field surveys of jatropha projects in Mozambique, Tanzania and Mali in 2012. The article singles out the salient economic and social impact results and derives lessons. The results clearly demonstrate the weak business case for jatropha biofuel production at this time. Plantations were found to be unviable because of insurmountable up-front capital requirements in combination with slow and unreliable crop maturation, inefficient oil pressing owing to a lack of scale and experience, inadequate utilization of by-products, and competitively-priced fossil diesel and palm oil. For smallholders, jatropha only has limited value as a hedge crop in environmentally and economically disadvantaged areas. Better prospects have to wait for the advent of improved jatropha varieties. Social impacts from the perspective of project managers were rather mixed: overall, food security perceptions were positive and no massive forced human displacements were noted so far, though some disputes over land access and compensation were reported. Labor legislation was apparently respected on plantations, and positive gender effects, regional income/employment effects and better public facilities were also reported. The projects generated considerable employment, albeit mostly of a temporary nature, as lack of economic viability had caused many projects to close down again. When introducing next-generation biofuel projects, better monitoring by various actor groups is recommended, as well as long-term investment plans that include integral exit strategies.

  8. Spatial point analysis based on dengue surveys at household level in central Brazil

    Science.gov (United States)

    Siqueira-Junior, João B; Maciel, Ivan J; Barcellos, Christovam; Souza, Wayner V; Carvalho, Marilia S; Nascimento, Nazareth E; Oliveira, Renato M; Morais-Neto, Otaliba; Martelli, Celina MT

    2008-01-01

    Background Dengue virus (DENV) affects nonimunne human populations in tropical and subtropical regions. In the Americas, dengue has drastically increased in the last two decades and Brazil is considered one of the most affected countries. The high frequency of asymptomatic infection makes difficult to estimate prevalence of infection using registered cases and to locate high risk intra-urban area at population level. The goal of this spatial point analysis was to identify potential high-risk intra-urban areas of dengue, using data collected at household level from surveys. Methods Two household surveys took place in the city of Goiania (~1.1 million population), Central Brazil in the year 2001 and 2002. First survey screened 1,586 asymptomatic individuals older than 5 years of age. Second survey 2,906 asymptomatic volunteers, same age-groups, were selected by multistage sampling (census tracts; blocks; households) using available digital maps. Sera from participants were tested by dengue virus-specific IgM/IgG by EIA. A Generalized Additive Model (GAM) was used to detect the spatial varying risk over the region. Initially without any fixed covariates, to depict the overall risk map, followed by a model including the main covariates and the year, where the resulting maps show the risk associated with living place, controlled for the individual risk factors. This method has the advantage to generate smoothed risk factors maps, adjusted by socio-demographic covariates. Results The prevalence of antibody against dengue infection was 37.3% (95%CI [35.5–39.1]) in the year 2002; 7.8% increase in one-year interval. The spatial variation in risk of dengue infection significantly changed when comparing 2001 with 2002, (ORadjusted = 1.35; p < 0.001), while controlling for potential confounders using GAM model. Also increasing age and low education levels were associated with dengue infection. Conclusion This study showed spatial heterogeneity in the risk areas of dengue

  9. Spatial point analysis based on dengue surveys at household level in central Brazil

    Directory of Open Access Journals (Sweden)

    Oliveira Renato M

    2008-10-01

    Full Text Available Abstract Background Dengue virus (DENV affects nonimunne human populations in tropical and subtropical regions. In the Americas, dengue has drastically increased in the last two decades and Brazil is considered one of the most affected countries. The high frequency of asymptomatic infection makes difficult to estimate prevalence of infection using registered cases and to locate high risk intra-urban area at population level. The goal of this spatial point analysis was to identify potential high-risk intra-urban areas of dengue, using data collected at household level from surveys. Methods Two household surveys took place in the city of Goiania (~1.1 million population, Central Brazil in the year 2001 and 2002. First survey screened 1,586 asymptomatic individuals older than 5 years of age. Second survey 2,906 asymptomatic volunteers, same age-groups, were selected by multistage sampling (census tracts; blocks; households using available digital maps. Sera from participants were tested by dengue virus-specific IgM/IgG by EIA. A Generalized Additive Model (GAM was used to detect the spatial varying risk over the region. Initially without any fixed covariates, to depict the overall risk map, followed by a model including the main covariates and the year, where the resulting maps show the risk associated with living place, controlled for the individual risk factors. This method has the advantage to generate smoothed risk factors maps, adjusted by socio-demographic covariates. Results The prevalence of antibody against dengue infection was 37.3% (95%CI [35.5–39.1] in the year 2002; 7.8% increase in one-year interval. The spatial variation in risk of dengue infection significantly changed when comparing 2001 with 2002, (ORadjusted = 1.35; p Conclusion This study showed spatial heterogeneity in the risk areas of dengue when using a spatial multivariate approach in a short time interval. Data from household surveys pointed out that low prevalence areas

  10. An InSAR-based survey of volcanic deformation in the central Andes

    Science.gov (United States)

    Pritchard, M. E.; Simons, M.

    2004-02-01

    We extend an earlier interferometric synthetic aperture radar (InSAR) survey covering about 900 remote volcanos of the central Andes (14°-27°S) between the years 1992 and 2002. Our survey reveals broad (10s of km), roughly axisymmetric deformation at 4 volcanic centers: two stratovolcanoes are inflating (Uturuncu, Bolivia, and Hualca Hualca, Peru); another source of inflation on the border between Chile and Argentina is not obviously associated with a volcanic edifice (here called Lazufre); and a caldera (Cerro Blanco, also called Robledo) in northwest Argentina is subsiding. We explore the range of source depths and volumes allowed by our observations, using spherical, ellipsoidal and crack-like source geometries. We further examine the effects of local topography upon the deformation field and invert for a spherical point-source in both elastic half-space and layered-space crustal models. We use a global search algorithm, with gradient search methods used to further constrain best-fitting models. Inferred source depths are model-dependent, with differences in the assumed source geometry generating a larger range of accepted depths than variations in elastic structure. Source depths relative to sea level are: 8-18 km at Hualca Hualca; 12-25 km for Uturuncu; 5-13 km for Lazufre, and 5-10 km at Cerro Blanco. Deformation at all four volcanoes seems to be time-dependent, and only Uturuncu and Cerro Blanco were deforming during the entire time period of observation. Inflation at Hualca Hualca stopped in 1997, perhaps related to a large eruption of nearby Sabancaya volcano in May 1997, although there is no obvious relation between the rate of deformation and the eruptions of Sabancaya. We do not observe any deformation associated with eruptions of Lascar, Chile, at 16 other volcanoes that had recent small eruptions or fumarolic activity, or associated with a short-lived thermal anomaly at Chiliques volcano. We posit a hydrothermal system at Cerro Blanco to explain the

  11. Knowledge-Based, Central Nervous System (CNS) Lead Selection and Lead Optimization for CNS Drug Discovery.

    Science.gov (United States)

    Ghose, Arup K; Herbertz, Torsten; Hudkins, Robert L; Dorsey, Bruce D; Mallamo, John P

    2012-01-18

    The central nervous system (CNS) is the major area that is affected by aging. Alzheimer's disease (AD), Parkinson's disease (PD), brain cancer, and stroke are the CNS diseases that will cost trillions of dollars for their treatment. Achievement of appropriate blood-brain barrier (BBB) penetration is often considered a significant hurdle in the CNS drug discovery process. On the other hand, BBB penetration may be a liability for many of the non-CNS drug targets, and a clear understanding of the physicochemical and structural differences between CNS and non-CNS drugs may assist both research areas. Because of the numerous and challenging issues in CNS drug discovery and the low success rates, pharmaceutical companies are beginning to deprioritize their drug discovery efforts in the CNS arena. Prompted by these challenges and to aid in the design of high-quality, efficacious CNS compounds, we analyzed the physicochemical property and the chemical structural profiles of 317 CNS and 626 non-CNS oral drugs. The conclusions derived provide an ideal property profile for lead selection and the property modification strategy during the lead optimization process. A list of substructural units that may be useful for CNS drug design was also provided here. A classification tree was also developed to differentiate between CNS drugs and non-CNS oral drugs. The combined analysis provided the following guidelines for designing high-quality CNS drugs: (i) topological molecular polar surface area of <76 Å(2) (25-60 Å(2)), (ii) at least one (one or two, including one aliphatic amine) nitrogen, (iii) fewer than seven (two to four) linear chains outside of rings, (iv) fewer than three (zero or one) polar hydrogen atoms, (v) volume of 740-970 Å(3), (vi) solvent accessible surface area of 460-580 Å(2), and (vii) positive QikProp parameter CNS. The ranges within parentheses may be used during lead optimization. One violation to this proposed profile may be acceptable. The

  12. Beyond the Central Dogma: Model-Based Learning of How Genes Determine Phenotypes

    Science.gov (United States)

    Reinagel, Adam; Speth, Elena Bray

    2016-01-01

    In an introductory biology course, we implemented a learner-centered, model-based pedagogy that frequently engaged students in building conceptual models to explain how genes determine phenotypes. Model-building tasks were incorporated within case studies and aimed at eliciting students' understanding of 1) the origin of variation in a population…

  13. Limited irrigation of corn-based no-till crop rotations in west central Great Plains.

    Science.gov (United States)

    Identifying the most profitable crop rotation for an area is a continuous research challenge. The objective of this study was to evaluate 2, 3, and 4 yr. limited irrigation corn (Zea mays L.) based crop rotations for grain yield, available soil water, crop water productivity, and profitability in co...

  14. Central Issues in the Use of Computer-Based Materials for High Volume Entrepreneurship Education

    Science.gov (United States)

    Cooper, Billy

    2007-01-01

    This article discusses issues relating to the use of computer-based learning (CBL) materials for entrepreneurship education at university level. It considers CBL as a means of addressing the increased volume and range of provision required in the current context. The issues raised in this article have importance for all forms of computer-based…

  15. Management and hazardous waste characterization in Central for Isotop and Radiation Application based on potential dangers

    International Nuclear Information System (INIS)

    Separating and storing hazardous waste have been done based on the physical, chemical, and based on potential dangers due to safety hazardous waste temporary storage warehouse. From the results of data collection in 2014 found that the most dominant hazardous waste is organic liquid waste which reaches 61 %, followed by inorganic liquid waste 33 % while organic solid waste and inorganic solid waste has a small portion. When viewed from potential danger, flammable liquid waste has the greatest volume percentage it is 47 % and is followed by a corrosive liquid waste 26 %, while the liquid waste that has not been identified is quite large, which is 9 %. From the highest hazard potential data, hazardous waste storage warehouse is required to have good air circulation and waste storage shelf protected from direct solar heat. Cooperation of lab workers and researchers are also indispensable in providing identification of each waste generated to facilitate the subsequent waste management. (author)

  16. Centralized Role-Based Access Control for Federated Multi-Domain Environments

    Institute of Scientific and Technical Information of China (English)

    YU Guangcan; LU Zhengding; LI Ruixuan; MUDAR Sarem

    2006-01-01

    The secure interaction among multiple security domains is a major concern. In this paper, we highlight the issues of secure interoperability among multiple security domains operating under the widely accepted Role Based Access Control (RBAC) model. We propose a model called CRBAC that easily establishes a global policy for roles mapping among multiple security domains. Our model is based on an extension of the RBAC model. Also, multiple security domains were composed to one abstract security domain. Also roles in the multiple domains are translated to permissions of roles in the abstract security domain. These permissions keep theirs hierarchies. The roles in the abstract security domain implement roles mapping among the multiple security domains. Then, authorized users of any security domain can transparently access resources in the multiple domains.

  17. DPSK signals demodulation based on a multimode fiber with a central dip

    OpenAIRE

    CHEN Xiaoyong; Rodriguez Horche, Paloma; Martín Minguez, Alfredo

    2014-01-01

    Differential Phase Shift Keying (DPSK) modulation format has been shown as a robust solution for next-generation optical transmission systems. One key device enabling such systems is a delay interferometer, converting the phase modulation signal into the intensity modulation signal to be detected by the photodiodes. Usually, a standard Mach-Zehnder interferometer (MZI) is used for demodulating a DPSK signal. In this paper, we develop an MZI which is based on all-fiber Multimode Interference (...

  18. Implementation of Central Dogma Based Cryptographic Algorithm in Data Warehouse Architecture for Performance Enhancement

    OpenAIRE

    Rajdeep Chowdhury; Soupayan Datta; Saswata Dasgupta; Mallika De

    2015-01-01

    Data warehouse is a set of integrated databases deliberated to expand decision-making and problem solving, espousing exceedingly condensed data. Data warehouse happens to be progressively more accepted theme for contemporary researchers with respect to contemporary inclination towards industry and executive purview. The crucial tip of the proposed work is integrated on delivering an enhanced and an exclusive innovative model based on the intention of enhancing security measures, which at time...

  19. ICT industry and resources based analysis of maintenance SME in the Central Europe

    Directory of Open Access Journals (Sweden)

    Š. Tesar

    2010-12-01

    Full Text Available Highly competitive situation in Information and Communication technology (ICT maintenance industryrequires a precise analysis of all important factors and carefully defined company strategy which addresses eachof these aspects. This paper presents a resource based analysis of family run SME, operating in IT parts andconsumables market. In order to understand this complex view, it first describes the company background. Itbriefly presents the industry key success factors and company strategy of the SME. The value chain analysishelps to name the main organization’s capabilities and evaluates them in terms of costs and customer willingnessto pay. Resource audit provides an analysis of key company tangible, intangible and human resources. Theoutcome of this audit shows that most of SME resources are of an intangible nature. Contrary to the highermobility of today’s resources, intangible resources of SME such as company reputation, culture and strategicbusiness relations, are mostly immobile and inimitable. Based on the audit all key resources and capabilities areappraised by their strength and importance relative to closest rivals. Results are presented in graph whichrecognizes the key strengths (family run business related and weaknesses (IT and finance. The results of theresourced based analysis lead to recommendations for changes in order to create and retain competitiveadvantage.

  20. Prevalence of Obesity and Overweight in an Indigenous Population in Central Brazil: A Population-Based Cross-Sectional Study

    Directory of Open Access Journals (Sweden)

    Geraldo F. Oliveira

    2015-10-01

    Full Text Available Objective: To estimate the prevalence of obesity and overweight and associated factors in indigenous people of the Jaguapiru village in Central Brazil. Methods: We conducted a population-based cross-sectional study between January 2009 and July 2011 in the adult native population of the Jaguapiru village, Central Brazil. Sociodemographic and lifestyle data were obtained; anthropometric measures, arterial blood pressure, and blood glucose were measured. The independent variables were tested by Poisson regression, and the interactions between them were analyzed. Results: 1,608 indigenous people (982 females, mean age 37.7 ± 15.1 years were included. The prevalence of obesity was 23.2% (95% CI 20.9-25.1%. Obesity was more prevalent among 40- to 49-year-old and overweight among 50- to 59-year-old persons. Obesity was positively associated with female sex, higher income, and hypertension. Among indigenous people, interactions were found with hypertension and sedentary lifestyle - hypertension in males and sedentary lifestyle in females. Conclusions: The prevalence of obesity and overweight in indigenous people of the Jaguapiru village is high. Males as well as hypertensive and higher family income individuals have higher rates. Sedentary lifestyle and hypertension leverage the rates of obesity. Prevention and adequate public health policies can be critical for the control of excess weight and its comorbidities among Brazilian indigenous people.

  1. Configuring calendar variation based on time series regression method for forecasting of monthly currency inflow and outflow in Central Java

    Science.gov (United States)

    Setiawan, Suhartono, Ahmad, Imam Safawi; Rahmawati, Noorgam Ika

    2015-12-01

    Bank Indonesia (BI) as the central bank of Republic Indonesiahas a single overarching objective to establish and maintain rupiah stability. This objective could be achieved by monitoring traffic of inflow and outflow money currency. Inflow and outflow are related to stock and distribution of money currency around Indonesia territory. It will effect of economic activities. Economic activities of Indonesia,as one of Moslem country, absolutely related to Islamic Calendar (lunar calendar), that different with Gregorian calendar. This research aims to forecast the inflow and outflow money currency of Representative Office (RO) of BI Semarang Central Java region. The results of the analysis shows that the characteristics of inflow and outflow money currency influenced by the effects of the calendar variations, that is the day of Eid al-Fitr (moslem holyday) as well as seasonal patterns. In addition, the period of a certain week during Eid al-Fitr also affect the increase of inflow and outflow money currency. The best model based on the value of the smallestRoot Mean Square Error (RMSE) for inflow data is ARIMA model. While the best model for predicting the outflow data in RO of BI Semarang is ARIMAX model or Time Series Regression, because both of them have the same model. The results forecast in a period of 2015 shows an increase of inflow money currency happened in August, while the increase in outflow money currency happened in July.

  2. Detection of planets in extremely weak central perturbation microlensing events via next-generation ground-based surveys

    CERN Document Server

    Chung, Sun-Ju; Koo, Jae-Rim

    2014-01-01

    Even though the recently discovered high-magnification event MOA-2010-BLG-311 had complete coverage over the peak, confident planet detection did not happen due to extremely weak central perturbations (fractional deviations of $\\lesssim 2\\%$). For confident detection of planets in extremely weak central perturbation (EWCP) events, it is necessary to have both high cadence monitoring and high photometric accuracy better than those of current follow-up observation systems.The next-generation ground-based observation project, KMTNet (Korea Microlensing Telescope Network), satisfies the conditions. We estimate the probability of occurrence of EWCP events with fractional deviations of $\\leq 2\\%$ in high-magnification events and the efficiency of detecting planets in the EWCP events using the KMTNet. From this study, we find that the EWCP events occur with a frequency of $> 50\\%$ in the case of $\\lesssim 100\\ M_{\\rm E}$ planets with separations of $0.2\\ {\\rm AU} \\lesssim d \\lesssim 20\\ {\\rm AU}$. We find that for m...

  3. Aetiologies of central nervous system infection in Viet Nam: a prospective provincial hospital-based descriptive surveillance study.

    Directory of Open Access Journals (Sweden)

    Nghia Ho Dang Trung

    Full Text Available BACKGROUND: Infectious diseases of the central nervous system (CNS remain common and life-threatening, especially in developing countries. Knowledge of the aetiological agents responsible for these infections is essential to guide empiric therapy and develop a rational public health policy. To date most data has come from patients admitted to tertiary referral hospitals in Asia and there is limited aetiological data at the provincial hospital level where most patients are seen. METHODS: We conducted a prospective Provincial Hospital-based descriptive surveillance study in adults and children at thirteen hospitals in central and southern Viet Nam between August 2007-April 2010. The pathogens of CNS infection were confirmed in CSF and blood samples by using classical microbiology, molecular diagnostics and serology. RESULTS: We recruited 1241 patients with clinically suspected infection of the CNS. An aetiological agent was identified in 640/1241 (52% of the patients. The most common pathogens were Streptococcus suis serotype 2 in patients older than 14 years of age (147/617, 24% and Japanese encephalitis virus in patients less than 14 years old (142/624, 23%. Mycobacterium tuberculosis was confirmed in 34/617 (6% adult patients and 11/624 (2% paediatric patients. The acute case fatality rate (CFR during hospital admission was 73/617 (12% in adults and to 42/624 (7% in children. CONCLUSIONS: Zoonotic bacterial and viral pathogens are the most common causes of CNS infection in adults and children in Viet Nam.

  4. Phylogeny and biogeography of Poecilia (Cyprinodontiformes: Poeciliinae) across Central and South America based on mitochondrial and nuclear DNA markers.

    Science.gov (United States)

    Ho, Adeljean L F C; Pruett, Christin L; Lin, Junda

    2016-08-01

    Poeciliids are a diverse group of small Neotropical fishes, and despite considerable research attention as models in ecology and evolutionary biology, our understanding of their biogeographic and phylogenetic relationships is still limited. We investigated the phylogenetic relationships of South and Central American Poecilia, by examining 2395 base pairs of mitochondrial DNA (ATPase 8/6, COI) and nuclear DNA (S7) for 18 species across six subgenera. Fifty-eight novel sequences were acquired from newly collected specimens and 20 sequences were obtained from previously published material. Analyses of concatenated and partitioned mitochondrial DNA and nuclear DNA sets resulted in a well-supported phylogeny that resolved several monophyletic groups corresponding to previously hypothesized subgenera and species complexes. A divergence-dating analysis supported the hypothesis of the genus Poecilia dispersing into Central America in the early Pliocene (ancestors of Psychropoecilia+Allopoecilia+Mollienesia: 7.3-2.0Mya) from predominantly South America. Subsequently, one lineage (subgenus Allopoecilia: 5.1-1.3Mya) expanded deeper into South America from Lower-Central America, and one lineage expanded from Nuclear-Central America into South America (subgenus Mollienesia: 0.71-0.14Mya). The subgenus Mollienesia diverged into three monophyletic groups that can be identified by nuptial male dorsal fin morphology and inner jaw dentition. A subclade of the unicuspid short-fins (subgenus Mollienesia) was the lineage that expanded into South America during the middle Pleistocene. Species in this subclade are now distributed across northern South America, where they are partially sympatric with Allopoecilia. However the P. (A.) caucana complex was not monophyletic, with P. (A.) wandae clustering in the Mollienesia subclade that expanded into South America. It is apparent that characters (body size, scale count, pigmentation, and gonopodium morphology) used to define the P. (A

  5. Stem and Progenitor Cell-Based Therapy of the Central Nervous System

    DEFF Research Database (Denmark)

    Goldman, Steven A

    2016-01-01

    A variety of neurological disorders are attractive targets for stem and progenitor cell-based therapy. Yet many conditions are not, whether by virtue of an inhospitable disease environment, poorly understood pathophysiology, or poor alignment of donor cell capabilities with patient needs. Moreover......, some disorders may be medically feasible targets but are not practicable, in light of already available treatments, poor risk-benefit and cost-benefit profiles, or resource limitations. This Perspective seeks to define those neurological conditions most appropriate for cell replacement therapy...

  6. The application of fuzzy-based methods to central nerve fiber imaging

    DEFF Research Database (Denmark)

    Axer, Hubertus; Jantzen, Jan; Keyserlingk, Diedrich Graf v.;

    2003-01-01

    This paper discusses the potential of fuzzy logic methods within medical imaging. Technical advances have produced imaging techniques that can visualize structures and their functions in the living human body. The interpretation of these images plays a prominent role in diagnostic and therapeutic....... Fuzzy logic methods were applied to analyze these pictures from low- to high-level image processing. The solutions presented here are motivated by problems of routine neuroanatomic research demonstrating fuzzy-based methods to be valuable tools in medical image processing....

  7. A role for fragment-based drug design in developing novel lead compounds for central nervous system targets

    Directory of Open Access Journals (Sweden)

    Michael J. Wasko

    2015-09-01

    Full Text Available Hundreds of millions of U.S. dollars are invested in the research and development of a single drug. Lead compound development is an area ripe for new design strategies. Therapeutic lead candidates have been traditionally found using high-throughput in vitro pharmacologic screening, a costly method for assaying thousands of compounds. This approach has recently been augmented by virtual screening, which employs computer models of the target protein to narrow the search for possible leads. A variant of virtual screening is fragment-based drug design, an emerging in silico lead discovery method that introduces low molecular weight fragments, rather than intact compounds, into the binding pocket of the receptor model. These fragments serve as starting points for growing the lead candidate. Current efforts in virtual fragment-based drug design within central nervous system (CNS targets are reviewed, as is a recent rule-based optimization strategy in which new molecules are generated within a 3D receptor binding pocket using the fragment as a scaffold. This process places special emphasis on creating synthesizable molecules but also exposes computational questions worth addressing. Fragment-based methods provide a viable, relatively low-cost alternative for therapeutic lead discovery and optimization that can be applied to CNS targets to augment current design strategies.

  8. Prevalence of tics in schoolchildren in central Spain: a population-based study.

    Science.gov (United States)

    Cubo, Esther; Gabriel y Galán, José María Trejo; Villaverde, Vanesa Ausín; Velasco, Sara Sáez; Benito, Vanesa Delgado; Macarrón, Jesús Vicente; Guevara, José Cordero; Louis, Elan D; Benito-León, Julián

    2011-08-01

    Tic disorders constitute a neurodevelopmental disorder of childhood. This study sought to determine the prevalence of tic disorders in a school-based sample. A randomized sample of 1158 schoolchildren, based on clusters (classrooms) in the province of Burgos (Spain), was identified on a stratified sampling frame combining types of educational center and setting (mainstream schools and special education), using a two-phase approach (screening and diagnosis ascertainment by a neurologist). Tics with/without impairment criterion were diagnosed according to Diagnostic and Statistical Manual of Mental Disorders criteria. In mainstream schools, tics were observed in 125/741 students (16.86%; 95% confidence interval, 14.10-19.63), and were more frequent in boys (87/448, 19.42%; 95% confidence interval, 15.64-23.19) compared with girls (38/293, 12.96%; 95% confidence interval, 8.95-16.98; P = 0.03). In special education centers, tics disorders were observed in 11/54 of children (20.37%; 95% confidence interval, 8.70-32.03). Overall, tics with impairment criteria were less frequent than tics without impairment criteria (4.65% vs 11.85%, P tics (6.07%) and Tourette syndrome (5.26%). Tic disorders are common in childhood, and the use or nonuse of impairment criteria exerts a significant impact on tic prevalence estimates. PMID:21763950

  9. Cladistics of some rattans (Calamus spp. from Central Sulawesi based on physical and mechanical characteristic of stems

    Directory of Open Access Journals (Sweden)

    ANDI TANRA TELLU

    2006-07-01

    Full Text Available The research of the physical and mechanical characteristic of rattans stem of 10 species of the genus Calamus from Bancea Nature Reserve and Lore Lindu National Park in Central Sulawesi had been conducted. The aims of this research were to describe phylogenetic relationship of those species based on physical and mechanical characteristic with cladistic approach (cladogram. The research had been used descriptive method, i.e. specific gravity, parallel attracting firmness of fiber, firmness stress parallels of flex firmness, and fiber/static curve. It was reconciled with standard of ASTM D no 143-52 with a few which has modified. The data was analyzed by ANOVA. The result indicated that the mechanical and physical characteristic of Calamus rattan can be made as distinguishing evidences. It can be compiled by a new classification in the form of cladistic (classification of numeric as complement of previous classification.

  10. Thanetian transgressive-regressive sequences based on foraminiferal paleobathymetry at Gebel Matulla, west-central Sinai, Egypt

    Science.gov (United States)

    Farouk, Sherif; Elamri, Zaineb; El-Sorogy, Abdelbaset

    2016-09-01

    Qualitative and quantitative analysis of Thanetian foraminiferal assemblages at Gebel Matulla in west-central Sinai has been carried out. Three benthic foraminiferal assemblages are recorded from shallowest to deepest as Cibicidoides pseudoacutus, Angulogavelinella avnimelechi, Gavelinella danica witch evidences of fluctuations from middle neritic to upper bathyal environments. Changes in the foraminiferal population enabled us to classify the Thanetian succession into two fourth order transgressive-regressive (T-R) sequences. Three sequence boundaries are identified, at the Selandian/Thanetian (S/T) boundary, within the Thanetian succession, and the Paleocene/Eocene (P/E) boundary. It occurs at the top part of the maximum regression associated with major discontinuities and changes in depositional regimes as well as vertical facies changes. Broad correlation with eustatic records based upon integrated microplanktonic biostratigraphy suggests that the fluctuations of foraminiferal population were controlled by global sea-level changes.

  11. Converting Nonliquid Crystals into Liquid Crystals by N-Methylation in the Central Linker of Triazine-Based Dendrimers.

    Science.gov (United States)

    Tsai, Meng-Jung; Hsieh, Jei-Way; Lai, Long-Li; Cheng, Kung-Lung; Liu, Shih-Hsien; Lee, Jey-Jau; Hsu, Hsiu-Fu

    2016-06-17

    Two triazine-based dendrimers were successfully prepared in 60-75% yields. These newly prepared dendrimers 2a and 2b containing the -NMe(CH2)2NMe- and the -NMe(CH2)4NMe- linkers between two G3 dendrons, respectively, exhibit columnar phases during the thermal process. However, the corresponding dendrimers 1a and 1b containing the -NH(CH2)2NH- and the -NH(CH2)4NH- linkers between two G3 dendrons, respectively, do not show any LC phases on thermal treatment. Computational investigations on molecular conformations reveal that N-methylation of the dendritic central linker leads dendrimers to possess more isomeric conformations and thus successfully converts non-LC dendrimers (1a and 1b) into LC dendrimers (2a and 2b). PMID:27203100

  12. Centrally controlled self-healing wavelength division multiplexing passive optical network based on optical carrier suppression technique

    Science.gov (United States)

    Zhu, Min; Zhang, Jiao; Sun, Xiaohan

    2015-12-01

    We proposed and demonstrated a centrally controlled and self-healing wavelength division multiplexing passive optical network with colorless optical network units (ONUs) based on optical carrier suppression technique. By switching the affected data in the OCS signal sideband to an alternate protection path, only one optical switch is provisioned at the optical line terminal, which is controlled by a logic control circuit upon monitoring of power outage on the working path. The proposed scheme can reliably protect against both distribution and feeder fiber failures. Moreover, gain-saturated reflective semiconductor optical amplifiers are used as colorless transmitters in ONUs. The protection scheme feasibility and system performances are experimentally verified with 10 Gb/s downstream and 1.25 Gb/s upstream data in both working and protection modes. The protection switching time was measured to be around 1 ms.

  13. Profile of adults seeking voluntary HIV testing and counseling in rural Central India: results from a hospital-based study.

    Science.gov (United States)

    Pai, Nitika Pant; Joshi, Rajnish; Moodie, Erica E M; Taksande, Bharati; Kalantri, S P; Pai, Madhukar; Tulsky, Jacqueline P; Reingold, Arthur

    2009-03-01

    Rural India has an undetected load of HIV-positive individuals. Few rural adults present for HIV testing and counseling due to stigma, discrimination, and fear of social ostracization. In this rural hospital clinic-based study, we document profiles of rural adults seeking voluntary testing and counseling, and analyze correlates of HIV seropositivity. This cross-sectional study was conducted in 450 participants presenting to the outpatient clinics of Mahatma Gandhi Institute of Medical Sciences, Sevagram, Central India. After informed consent, pre- and post-test counseling, HIV testing, and face-to-face interviews were conducted. Data were collected using a structured questionnaire. The median age of the 450 study participants was 34 years (range 18-88 years); the majority (74%) was married. The overall proportion of HIV seropositivity was 32% [95% CI 28%, 37%]. The proportions of HIV seropositivity in married women, married men, and single men were 41%, 37%, 18%, respectively. No single woman was found seropositive in the study. Very few married women were aware of their husbands' HIV status. In a multivariate analysis, correlates of HIV seropositivity in men were: age 30-39 years, being married, having sex with multiple partners, use of alcohol before sex, and testing positive for HIV in the past. In married women, the only predictor of seropositivity was being married. Although limited by the non-random nature of the sampling method, this pilot study is unique in that it is the first from this rural region of Central India. It provides baseline data on marginalized, largely unstudied populations that may aid in designing probabilistic community-based surveys in this neglected population.

  14. Chordoma versus chondrosarcoma of the central skull base: MR and CT findings

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Guk Myeong; Han, Moon Hee; Chang, Kee Hyun; Kim, Hong Dae; Yeon, Kyung Mo [Seoul National Univ. (Korea, Republic of). Coll. of Medicine; Yu, In Kyu [Uulji Hospital, Seoul (Korea, Republic of); Kim, Sam Soo [Boramae Hospital, Seoul (Korea, Republic of)

    1998-02-01

    It is known that due to both their imaging and pathologic features, the accurate differentiation of chondrosarcoma from chordoma is difficult. Through an analysis of MR and CT finding, this study aims to determine the differential points between these two tumors. In 21 patients, CT and MR imaging studies of chordoma (n=12) and chondrosarcoma (n=9) at the base of the skull were retrospectively reviewed. Diagnosis had been established by histologic examination of surgically removed specimens. Eleven of the chordomas were subclassified as conventional and one as chondroid ; eight chondrosarcoma were conventional and one was myxoid. Four chordoma patients underwent CT and MR ; in six, only MR was in one, only CT was performed. All scans were retrospectively evaluated for the location (midline/off-midline), direction of extension, margin and shape, bony destruction and calcification, MR signal intensity and enhancement patterns of the tumors. Degree of calcification was graded from I to II. Although MR and CT findings were similar in both types of tumor, location and degree of calcification may be features which usefully distinguish chordoma from chondrosarcoma. (author). 17 refs., 2 tabs., 5 figs.

  15. Surface displacement based shape analysis of central brain structures in preterm-born children

    Science.gov (United States)

    Garg, Amanmeet; Grunau, Ruth E.; Popuri, Karteek; Miller, Steven; Bjornson, Bruce; Poskitt, Kenneth J.; Beg, Mirza Faisal

    2016-03-01

    Many studies using T1 magnetic resonance imaging (MRI) data have found associations between changes in global metrics (e.g. volume) of brain structures and preterm birth. In this work, we use the surface displacement feature extracted from the deformations of the surface models of the third ventricle, fourth ventricle and brainstem to capture the variation in shape in these structures at 8 years of age that may be due to differences in the trajectory of brain development as a result of very preterm birth (24-32 weeks gestation). Understanding the spatial patterns of shape alterations in these structures in children who were born very preterm as compared to those who were born at full term may lead to better insights into mechanisms of differing brain development between these two groups. The T1 MRI data for the brain was acquired from children born full term (FT, n=14, 8 males) and preterm (PT, n=51, 22 males) at age 8-years. Accurate segmentation labels for these structures were obtained via a multi-template fusion based segmentation method. A high dimensional non-rigid registration algorithm was utilized to register the target segmentation labels to a set of segmentation labels defined on an average-template. The surface displacement data for the brainstem and the third ventricle were found to be significantly different (p preterm birth.

  16. Beyond the Central Dogma: Model-Based Learning of How Genes Determine Phenotypes.

    Science.gov (United States)

    Reinagel, Adam; Bray Speth, Elena

    2016-01-01

    In an introductory biology course, we implemented a learner-centered, model-based pedagogy that frequently engaged students in building conceptual models to explain how genes determine phenotypes. Model-building tasks were incorporated within case studies and aimed at eliciting students' understanding of 1) the origin of variation in a population and 2) how genes/alleles determine phenotypes. Guided by theory on hierarchical development of systems-thinking skills, we scaffolded instruction and assessment so that students would first focus on articulating isolated relationships between pairs of molecular genetics structures and then integrate these relationships into an explanatory network. We analyzed models students generated on two exams to assess whether students' learning of molecular genetics progressed along the theoretical hierarchical sequence of systems-thinking skills acquisition. With repeated practice, peer discussion, and instructor feedback over the course of the semester, students' models became more accurate, better contextualized, and more meaningful. At the end of the semester, however, more than 25% of students still struggled to describe phenotype as an output of protein function. We therefore recommend that 1) practices like modeling, which require connecting genes to phenotypes; and 2) well-developed case studies highlighting proteins and their functions, take center stage in molecular genetics instruction. PMID:26903496

  17. Climate Based Façade Design for Business Buildings with Examples from Central London

    Directory of Open Access Journals (Sweden)

    John Napier

    2015-01-01

    Full Text Available There is a disconnection between commercial architecture and environmental thinking, where green features can be included as part of a strategy for gaining approvals and marketing projects, but those features are not reviewed after completion and occupation of the building and knowledge is not shared. High levels of air conditioning are still considered unavoidable. Elaborate double skin façades and complex motorized shading systems are adopted; often masking an underlying lack of basic environmental thinking. This article returns (in principle to the physics of comfort in buildings and the passive strategies which can help achieve this with a low energy and carbon footprint. Passive and active façade design strategies are outlined as the basis of a critical tool and a design methodology for new projects. A new architectural sensibility can arise based on modeling the inputs of sunlight, daylight and air temperature in time and space at the early stages of design. Early but sound strategies can be tested and refined using advanced environmental modeling techniques. Architecture and environmental thinking can proceed hand in hand through the design process.

  18. ScienceCentral: open access full-text archive of scientific journals based on Journal Article Tag Suite regardless of their languages

    OpenAIRE

    Huh, Sun

    2013-01-01

    ScienceCentral, a free or open access, full-text archive of scientific journal literature at the Korean Federation of Science and Technology Societies, was under test in September 2013. Since it is a Journal Article Tag Suite-based full text database, extensible markup language files of all languages can be presented, according to Unicode Transformation Format 8-bit encoding. It is comparable to PubMed Central: however, there are two distinct differences. First, its scope comprises all scienc...

  19. Is violence associated with increased risk behavior among MSM? Evidence from a population-based survey conducted across nine cities in Central America

    OpenAIRE

    Wheeler, Jennifer; Anfinson, Katherine; Valvert, Dennis; Lungo, Susana

    2014-01-01

    Background/Objective: There is a dearth of research examining the linkages between violence and HIV risk behavior among men who have sex with men (MSM), including those who identify as transgender women (TW), particularly in Central America where violence is widespread. In this paper, we use population-based survey results to independently examine the correlations between physical, emotional and sexual violence and HIV risk behavior among MSM populations in five countries in Central America.D...

  20. Simulation Platform of Underwater Quadruped Walking Robot Based on MotionGenesis Kane 5 3 and Central Pattern Generator

    Institute of Scientific and Technical Information of China (English)

    Ke Yang; XuYang Wang; Tong Ge; Chao Wu

    2014-01-01

    It will still in lack of a simulation platform used to learn the walking of underwater quadruped walking robot. In order to alleviate this shortage, a simulation platform for the underwater quadruped walking robot based on Kane dynamic model and CPG-based controller is constructed. The Kane dynamic model of the underwater quadruped walking robot is processed with a commercial package MotionGenesis Kane 5�3. The forces between the feet and ground are represented as a spring and damper. The relation between coefficients of spring and damper and stability of underwater quadruped walking robot in the stationary state is studied. The CPG-based controller consisted of Central Pattern Generator ( CPG) and PD controller is presented, which can be used to control walking of the underwater quadruped walking robot. The relation between CPG parameters and walking speed of underwater quadruped walking robot is investigated. The relation between coefficients of spring and damper and walking speed of underwater quadruped walking robot is studied. The results show that the simulation platform can imitate the stable walking of the underwater quadruped walking robot.

  1. Biomonitoring of trace metals (Cu, Cd, Cr, Hg, Pb, Zn in Mali Ston Bay (eastern Adriatic using the Mediterranean blue mussel (1998-2005

    Directory of Open Access Journals (Sweden)

    Tomislav ZVONARIĆ

    2007-06-01

    Full Text Available In Mali Ston Bay, located on the eastern Adriatic coast, mussels and oysters have traditionally been cultivated. However, previous studies showed that water and sediments from Mali Ston Bay contain elevated levels of some trace metals, which was attributed to natural processes of sedimentation and drainage. In order to assess the bioavailability of trace metals in the bay, and to assess the health risk of consumption of shellfish species from Mali Ston Bay, a passive monitoring program was carried out in the period from December 1998 to August 2005. Samples of the whole soft tissue were collected seasonally at 4 shellfish breeding farms and analyzed for essential (Cu, Zn and non-essential (Cd, Cr, THg, Pb metals. Mean concentrations of analyzed metals in the edible tissue of mussels (Cd: 1.15 mg kg-1 d.wt.; Cr: 1.65 mg kg-1 d.wt.; Cu: 5.6 mg kg-1 d.wt.; THg: 0.15 mg kg-1 d.wt.; Pb: 1.09 mg kg-1 d.wt.; Zn: 139 mg kg-1 d.wt. fell in the range of values usually found in low to moderately contaminated marine coastal areas. Examination of the spatial pattern of contaminants showed that there were no statistically significant differences among stations in Mali Ston Bay regarding trace metal content. Concentrations of Cd, Cu, Cr and THg were significantly higher during the autumn-winter period, while concentrations of Pb and Zn did not depend on the sampling season. Among six analyzed metals, only concentrations of Cd and THg were significantly negatively correlated with the condition index of the mussels. Analysis of temporal trends during the 7 years of monitoring showed that metal concentrations had not changed with time. According to EU and WHO legislation, consumption of the edible tissue of the mussels was not harmful for humans since all the values were well below the permissible limits for fresh seafood. In addition, results of the evaluation of the risks to human health associated with consumption of the mussels containing trace metals suggest

  2. THE MILITARY COUP IN MALI, 22 MARCH 2012. REFLECTIONS ON THE DEMISE OF DEMOCRACY AND THE IMPORTANCE OF CIVIL – MILITARY RELATIONS

    Directory of Open Access Journals (Sweden)

    Thomas C. BRUNEAU

    2014-04-01

    Full Text Available The coup in Bamako, on 22 March 2012 both gave lie to the apparent stability of Mali as a democratic country and resulted in the taking of power of an assortment of armed combatants in the North of the country, which resulted in armed intervention by France. This article is about the coup itself that created the power vacuum allowing the insurrection to grow and ultimately take power in the North. The authors have developed a framework for analyzing civil – military relations they believe is more useful than other available frameworks in understanding the role of the military in politics.

  3. The N Terminus of the Escherichia coli Transcription Activator MalT Is the Domain of Interaction with MalY

    OpenAIRE

    Schlegel, Anja; Danot, Olivier; Richet, Evelyne; Ferenci, Thomas; Boos, Winfried

    2002-01-01

    The maltose system of Escherichia coli consists of a number of genes encoding proteins involved in the uptake and metabolism of maltose and maltodextrins. The system is positively regulated by MalT, its transcriptional activator. MalT activity is controlled by two regulatory circuits: a positive one with maltotriose as effector and a negative one involving several proteins. MalK, the ATP-hydrolyzing subunit of the cognate ABC transporter, MalY, an enzyme with the activity of a cystathionase, ...

  4. Mapping of leptospirosis risk factor based on remote sensing image in Tembalang, Semarang City, Central Java

    Directory of Open Access Journals (Sweden)

    Sunaryo Sunaryo

    2012-09-01

    of leptospirosis, physical environment of risk factor analysis.Methods: This cross sectional design consisted of 246 leptospirosis subjects mapped with GPS, and processed by using ArcGis 92 program. Leptospirosis case was overlaid with remote sensing (Quickbird image, then is done interpretation of spatial feature, and digitation on screen to visual identify of risk factor.Results: Based on digital visualization leptospirosis cases in 2009 were clustered in Tembalang with shortest distance index 0,009 km and is furthermost 18 km. More case distribution found at children and men adolescent. Temporally, case increased in the dry season, among of July and August. Result of visual interpretation and digitation can obtain land use map, water body, settlement, fl oods area, vegetation index and height.Conclusion: Spatial high resolution remote sensing image is very good for mapping of leptospirosis risk factor. Leptospirosis case distribution forms the cluster in Tembalang; case is predominated by children andmen adolescent. (Health Science Indones 2012;1:45-50 

  5. The free caesareans policy in low-income settings: an interrupted time series analysis in Mali (2003-2012.

    Directory of Open Access Journals (Sweden)

    Pierre Fournier

    Full Text Available INTRODUCTION: Several countries have instituted fee exemptions for caesareans to reduce maternal and newborn mortality. OBJECTIVES: To evaluate the effect of fee exemptions for caesareans on population caesarean rates taking into account different levels of accessibility. METHODS: The observation period was from January 2003 to May 2012 in one Region and covered 11.7 million person-years. Exemption fees for caesareans were adopted on June 26, 2005. Data were obtained from a registration system implemented in 2003 that tracks all obstetrical emergencies and interventions including caesareans. The pre-intervention period was 30 months and the post-intervention period was 83 months. We used an interrupted time series to evaluate the trend before and after the policy adoption and the overall tendency. FINDINGS: During the study period, the caesarean rate increased from 0.25 to 1.5% for the entire population. For women living in cities with district hospitals that provided caesareans, the rate increased from 1.7% before the policy was enforced to 5.7% 83 months later. No significant change in trends was observed among women living in villages with a healthcare centre or those in villages with no healthcare facility. For the latter, the caesarean rate increased from 0.4 to 1%. CONCLUSIONS: After nine years of implementation policy in Mali, the caesarean rate achieved in cities with a district hospital reached the full beneficial effect of this measure, whereas for women living elsewhere this policy did not increase the caesarean rate to a level that could contribute effectively to reduce their risk of maternal death. Only universal access to this essential intervention could reduce the inequities and increase the effectiveness of this policy.

  6. Access and use of interventions to prevent and treat malaria among pregnant women in Kenya and Mali: a qualitative study.

    Directory of Open Access Journals (Sweden)

    Jenny Hill

    Full Text Available Coverage of malaria in pregnancy interventions in sub-Saharan Africa is suboptimal. We undertook a systematic examination of the operational, socio-economic and cultural constraints to pregnant women's access to intermittent preventive treatment (IPTp, long-lasting insecticide-treated nets (LLINs and case management in Kenya and Mali to provide empirical evidence for strategies to improve coverage.Focus group discussions (FGDs were held as part of a programme of research to explore the delivery, access and use of interventions to control malaria in pregnancy. FGDs were held with four sub-groups: non-pregnant women of child bearing age (aged 15-49 years, pregnant women or mothers of children aged <1 year, adolescent women, and men. Content analysis was used to develop themes and sub-themes from the data.Women and men's perceptions of the benefits of antenatal care were generally positive; motivation among women consisted of maintaining a healthy pregnancy, disease prevention in mother and foetus, checking the position of the baby in preparation for delivery, and ensuring admission to a facility in case of complications. Barriers to accessing care related to the quality of the health provider-client interaction, perceived health provider skills and malpractice, drug availability, and cost of services. Pregnant women perceived themselves and their babies at particular risk from malaria, and valued diagnosis and treatment from a health professional, but cost of treatment at health facilities drove women to use herbal remedies or drugs bought from shops. Women lacked information on the safety, efficacy and side effects of antimalarial use in pregnancy.Women in these settings appreciated the benefits of antenatal care and yet health services in both countries are losing women to follow-up due to factors that can be improved with greater political will. Antenatal services need to be patient-centred, free-of-charge or highly affordable and accountable

  7. Dairy farms typology and management of animal genetic resources in the peri-urban zone of Bamako (Mali

    Directory of Open Access Journals (Sweden)

    Abdoulaye Toure

    2015-05-01

    Full Text Available Facing growth in demand, dairy production in peri-urban areas of developing countries is changing rapidly. To characterise this development around Bamako (Mali, this study establishes a typology of dairy production systems with a special focus on animal genetic resources. The survey included 52 dairy cattle farms from six peri-urban sites. It was conducted in 2011 through two visits, in the dry and harvest seasons. The median cattle number per farm was 17 (range 5–118 and 42% of farmers owned cropland (8.3± 7.3 ha, minimum 1 ha, maximum 25 ha. Feeding strategy was a crucial variable in farm characterisation, accounting for about 85% of total expenses. The use of artificial insemination and a regular veterinary follow-up were other important parameters. According to breeders’ answers, thirty genetic profiles were identified, from local purebreds to different levels of crossbreds. Purebred animals raised were Fulani Zebu (45.8 %, Maure Zebu (9.2 %, Holstein (3.0 %, Azawak Zebu (1.3 %, Mere Zebu (0.5% and Kuri taurine (0.1 %. Holstein crossbred represented 30.5% of the total number of animals (19.0% Fulani-Holstein, 11.2% Maure-Holstein and 0.3% Kuri-Holstein. Montbéliarde, Normande and Limousin crossbreds were also found (6.6 %, 0.7% and 0.3 %, respectively. A multivariate analysis helped disaggregate the diversity of management practices. The high diversity of situations shows the need for consideration of typological characteristics for an appropriate intervention. Although strongly anchored on local breeds, the peri-urban dairy systems included a diversity of exotic cattle, showing an uncoordinated quest of breeders for innovation. Without a public intervention, this dynamic will result in an irremediable erosion of indigenous animal genetic resources.

  8. Biochemical and fatty acid composition of Arca noae (Bivalvia: Arcidae from the Mali Ston Bay, Adriatic Sea

    Directory of Open Access Journals (Sweden)

    I. DUPCIC RADIC

    2014-09-01

    Full Text Available Biochemical and fatty acid composition of the bivalve Arca noae were investigated in the Mali Ston Bay in relation to environmental conditions. Sampling was carried out monthly, from December 2001 to November 2002. Wet shellfish meat consists on average of 77.61% water and 22.39% dry matter, while dry shellfish meat consists on average of 89.04% organic and 10.96% inorganic matter. PCA analysis identified temperature, nitrate, silicate, MICRO, Chl a and salinity as the most important environmental factors influencing biochemical composition of A. noae. An increase of dry weight content of A. noae was observed during the spring when both the sea temperature and food supply increased rapidly. Contents of protein (54.39-62.06% of dry weight, carbohydrate (4.13-8.07% of dry weight and lipid (3.46-8.58% of dry weight varied significantly during the year. Protein and lipid level reached the maximum value in June. The fatty acid profiles of total lipids extracted from A. noae showed high level of unsaturation (UNS/SAT 1.9-3.4. Total polyunsaturated fatty acids (PUFA represented the majority of total fatty acids (40.3-59.9% of total fatty acids and the most abundant were eicosapentaenoic (20:5n-3 and docosahexaenoic (22:6n-3 acid. n-3/n-6 PUFA ratio value varied between 2.1 and 5.0 and was the highest during the spring (April to June. Due to their low lipid and high percentages of healthy polyunsaturated fatty acids A. noae can be evaluated as a quality seafood product. The most suitable period of the year for its consumption is in the spring when it reaches its highest nutritional values.

  9. Evidences of Neotectonic Movements Recorded in Fluvial and Lacustrine Deposits of the Niger River in Bamako, Mali

    Science.gov (United States)

    Dembele, N. D. J.

    2015-12-01

    Two alluvial profiles showing evidences of tectonic movements were discovered along the right bank of the Niger River at Bamako. The first profile of 25 meters thick is composed of a laminated silt layer of about 22 meters, of a gray sand layer of 25 cm and a pebble layer of 2 meters. A layer of 80 cm wide, an intrusive body, crosscuts the silt layers. The Grain size and heavy minerals analysis showed that this vertical layer is different in structure, texture and composition from the other layers. The second profile of about 20 meters is composed of interbedded fluvial gravel and sand deposits. The tectonic evidences found on those layers are of three types: faults and fractures, folds and the intrusion between silts deposits of the sand layers previously presented. The faults and fractures are located mainly on the fluvial gravel and sand deposits, whereas the silts deposits are folded and show some microfaults. The intrusion of a sand layer between the silt layer is a geological process that is not yet well understood but it is believed that this phenomena occurs during earthquakes as the sand layer during such event behave as a liquid. The discovery of such layer testifies that earthquakes used to happen in the area. As they concern only the alluvial deposits, their age should be no more than the Quaternary period. The presence of such tectonic evidences is surprising as Bamako like all the Republic of Mali is located on the west African craton that is supposed to be tectonically stable and their occurrence on Quaternary unconsolidated sediments shows that tectonic movements used to occur on that area during the last 2 millions years or may be less whereas people continue to build houses and other social infrastructures on them without any caution.

  10. Seasonal Malaria Chemoprevention with Sulphadoxine-Pyrimethamine and Amodiaquine Selects Pfdhfr-dhps Quintuple Mutant Genotype in Mali

    Science.gov (United States)

    Maiga, Hamma; Lasry, Estrella; Diarra, Modibo; Sagara, Issaka; Bamadio, Amadou; Traore, Aliou; Coumare, Samba; Bahonan, Soma; Sangare, Boubou; Dicko, Yeyia; Diallo, Nouhoum; Tembely, Aly; Traore, Djibril; Niangaly, Hamidou; Dao, François; Haidara, Aboubecrine; Dicko, Alassane; Doumbo, Ogobara K.; Djimde, Abdoulaye A.

    2016-01-01

    Background Seasonal malaria chemoprevention (SMC) with sulphadoxine-pyrimethamine (SP) plus amodiaquine (AQ) is being scaled up in Sahelian countries of West Africa. However, the potential development of Plasmodium falciparum resistance to the respective component drugs is a major concern. Methods Two cross-sectional surveys were conducted before (August 2012) and after (June 2014) a pilot implementation of SMC in Koutiala, Mali. Children aged 3–59 months received 7 rounds of curative doses of SP plus AQ over two malaria seasons. Genotypes of P. falciparum Pfdhfr codons 51, 59 and 108; Pfdhps codons 437 and 540, Pfcrt codon 76 and Pfmdr1codon 86 were analyzed by PCR on DNA from samples collected before and after SMC, and in non-SMC patient population as controls (November 2014). Results In the SMC population 191/662 (28.9%) and 85/670 (12.7%) of children were P. falciparum positive by microscopy and were included in the molecular analysis before (2012) and after SMC implementation (2014), respectively. In the non-SMC patient population 220/310 (71%) were successfully PCR analyzed. In the SMC children, the prevalence of all molecular markers of SP resistance increased significantly after SMC including the Pfdhfr-dhps quintuple mutant genotype, which was 1.6% before but 7.1% after SMC (p = 0.02). The prevalence of Pfmdr1-86Y significantly decreased from 26.7% to 15.3% (p = 0.04) while no significant change was seen for Pfcrt 76T. In 2014, prevalence of all molecular markers of SP resistance were significantly higher among SMC children compared to the non-SMC population patient (p falciparum resistance to SP in the treated children. However, there was no significant increase of these markers of resistance in the general parasite population after 2 years and 7 rounds of SMC. PMID:27662368

  11. Reconstruction of Oceanographic Changes Based on the Diatom Records of the Central Okhotsk Sea over the last 500000 Years

    Directory of Open Access Journals (Sweden)

    Wei-Lung Wang and Liang-Chi Wang

    2008-01-01

    Full Text Available This study provides insight into changes in sea ice conditions and the oceanographic environment over the past 500 kyr through analysis of the diatom record. Based on the relative abundance of 13 diatoms species in piston core MD012414, four types of environmental conditions in the central Okhotsk Sea over the last 330 ka BP have been distinguished: (1 open-ocean alternating with seasonal sea-ice cover in Stages 9, 5, and 1; (2 almost open-ocean free of sea-ice cover in Stages 7 and 3; (3 perennial sea-ice cover in Stages 6, 4, and 2; and (4 a warm ice-age dominated by open ocean assemblages in Stage 8. The littoral diatom species, Paralia sulcata, showed a sudden increase from the glacial period to the nterglacial period over the last 330 ka BP, except during Stage 8. Such a result implies that melting sea-ice transported terrigenous materials from the north Okhotsk Sea continental shelves to the central ocean during eglaciation. From Stage 13 to Stage 10, however, cold and warm marine conditions unexpectedly occurred in the late interglacial periods and the glacial periods, respectively. One possible reason for this is a lack of age control points from Stage 13 to Stage 10, and the different sediment accumulation rates between glacial and interglacial periods. This study suggests not only the process by which oceanographic variation of sea ice occurred, but also new significance for Paralia sulcata as an indicator in the diatom record of the Okhotsk Sea.

  12. The optimal fractional S transform of seismic signal based on the normalized second-order central moment

    Science.gov (United States)

    Wang, Yuqing; Peng, Zhenming

    2016-06-01

    As the extension of time-bandwidth product (TBP) in the fractional domain, the generalized time-bandwidth product (GTBP) provides a rotation-independent measure of compactness. A new fractional S transform (FrST) is proposed to avoid missing the physical meaning of the fractional time-frequency plane. FrST is based on the GTBP criterion and the time-frequency rotation property of fractional Fourier transform (FrFT). In addition, we introduce the normalized second-order central moment (NSOCM) calculation method to determine the optimal order. The optimal order searching process can be converted into the NSOCM calculation. Compared with TBP search algorithms, the NSOCM approach has higher computational efficiency. The qualitative advantage of the NSOCM approach in the optimal order selection is demonstrated by a series of model tests. The optimal FrST based on NSOCM (OFrST) can produce more compact time-frequency support than the S transform. The real seismic data spectral decomposition results show that the proposed algorithm can obtain single-frequency visualization with better time-frequency concentration, thereby enhancing the precision of reservoir prediction.

  13. A central support system can facilitate implementation and sustainability of a Classroom-based Undergraduate Research Experience (CURE) in Genomics.

    Science.gov (United States)

    Lopatto, David; Hauser, Charles; Jones, Christopher J; Paetkau, Don; Chandrasekaran, Vidya; Dunbar, David; MacKinnon, Christy; Stamm, Joyce; Alvarez, Consuelo; Barnard, Daron; Bedard, James E J; Bednarski, April E; Bhalla, Satish; Braverman, John M; Burg, Martin; Chung, Hui-Min; DeJong, Randall J; DiAngelo, Justin R; Du, Chunguang; Eckdahl, Todd T; Emerson, Julia; Frary, Amy; Frohlich, Donald; Goodman, Anya L; Gosser, Yuying; Govind, Shubha; Haberman, Adam; Hark, Amy T; Hoogewerf, Arlene; Johnson, Diana; Kadlec, Lisa; Kaehler, Marian; Key, S Catherine Silver; Kokan, Nighat P; Kopp, Olga R; Kuleck, Gary A; Lopilato, Jane; Martinez-Cruzado, Juan C; McNeil, Gerard; Mel, Stephanie; Nagengast, Alexis; Overvoorde, Paul J; Parrish, Susan; Preuss, Mary L; Reed, Laura D; Regisford, E Gloria; Revie, Dennis; Robic, Srebrenka; Roecklien-Canfield, Jennifer A; Rosenwald, Anne G; Rubin, Michael R; Saville, Kenneth; Schroeder, Stephanie; Sharif, Karim A; Shaw, Mary; Skuse, Gary; Smith, Christopher D; Smith, Mary; Smith, Sheryl T; Spana, Eric P; Spratt, Mary; Sreenivasan, Aparna; Thompson, Jeffrey S; Wawersik, Matthew; Wolyniak, Michael J; Youngblom, James; Zhou, Leming; Buhler, Jeremy; Mardis, Elaine; Leung, Wilson; Shaffer, Christopher D; Threlfall, Jennifer; Elgin, Sarah C R

    2014-01-01

    In their 2012 report, the President's Council of Advisors on Science and Technology advocated "replacing standard science laboratory courses with discovery-based research courses"-a challenging proposition that presents practical and pedagogical difficulties. In this paper, we describe our collective experiences working with the Genomics Education Partnership, a nationwide faculty consortium that aims to provide undergraduates with a research experience in genomics through a scheduled course (a classroom-based undergraduate research experience, or CURE). We examine the common barriers encountered in implementing a CURE, program elements of most value to faculty, ways in which a shared core support system can help, and the incentives for and rewards of establishing a CURE on our diverse campuses. While some of the barriers and rewards are specific to a research project utilizing a genomics approach, other lessons learned should be broadly applicable. We find that a central system that supports a shared investigation can mitigate some shortfalls in campus infrastructure (such as time for new curriculum development, availability of IT services) and provides collegial support for change. Our findings should be useful for designing similar supportive programs to facilitate change in the way we teach science for undergraduates. PMID:25452493

  14. Optimization of the preparation of sonogenic phospholipids-based microbubbles by using central composite experimental design and response surface methodology.

    Science.gov (United States)

    Zhao, Ying-Zheng; Lu, Cui-Tao; Mei, Xin-Guo

    2008-08-01

    Sonogenic microbubble agent is a newly developed drug targeting delivery system, which uses ultrasonic beam to enhance the delivery of drug and gene to targeted cells and tissues. In this paper, the preparation of sonogenic phospholipids-based microbubbles was optimized by using central composite experimental design (CCD) and response surface methodology (RSM). Hydrogenated egg phosphatidylcholine (EPC), Tween 80 and polyethylene glycol 1500 (PEG 1500) were important components affecting the concentration of 2 - 8 microm microbubbles in the preparation. The combined effects of these three factors were analyzed by CCD and optimized by RSM. Evaluation variable was the concentration of 2 - 8 microm microbubbles. Overall desirability was fitted to a second-order polynomial equation, through which three dimensional response surface graphs were produced. Optimal experimental conditions were selected from the stationary point of the response surfaces. The stability of the sonogenic phospholipids-based microbubbles by the optimal formulation was investigated by accelerated experiment. The contrast effect in vivo of the optimal formulation was investigated. Foreign market product SonoVue was used as the control. From the results, all the three factors had positive effects on the concentration of 2 - 8 microm microbubbles. The optimal condition in the preparation of phospholipids-based microbubbles was obtained as following: EPC 8.35 mg, Tween 80 21.68 mg and PEG 1500 201 mg. The mean value of the concentration of 2 - 8 microm microbubbles in rechecking experiment reached 8.60 x 10(9) x mL(-1). From the accelerated experiment, phospholipids-based microbubbles showed good physical stability. The intensity (relative unit) and duration of the contrast effect by the optimal formulation were 4.47 +/- 0.15 and (302 +/- 7) s respectively, which showed little difference with foreign market product SonoVue [4.28 +/- 0.13, (309 +/- 8) s]. The optimal formulation selected by CCD and

  15. Calculation of centrality bias factors in $p$+A collisions based on a positive correlation of hard process yields with underlying event activity

    CERN Document Server

    Perepelitsa, Dennis V

    2014-01-01

    Hard scattering yields in centrality-selected proton-- and deuteron--nucleus ($p$+A) collisions are generally compared to nucleon--nucleon ($NN$) cross-sections scaled to the appropriate partonic luminosity using geometric models derived from an analysis of minimum bias $p$+A interactions. In general, these models assume that hard process rates and the magnitude of the soft event activity in the underlying $NN$ collisions is uncorrelated. When included, these correlations influence the measured yield in a nominal centrality interval, an effect typically referred to as a "centrality bias". In this work, the impact of a positive correlation between the hard scattering yield and the underlying event activity in individual $NN$ collisions is investigated. This correlation is incorporated into the centrality calculations used by ATLAS and PHENIX, both based on a similar Monte Carlo Glauber approach but with different models of the per-collision or per-participant event activity. It is found that the presence of th...

  16. Application of a process-based shallow landslide hazard model over a broad area in Central Italy

    Science.gov (United States)

    Gioia, Eleonora; Speranza, Gabriella; Ferretti, Maurizio; Godt, Jonathan W.; Baum, Rex L.; Marincioni, Fausto

    2015-01-01

    Process-based models are widely used for rainfall-induced shallow landslide forecasting. Previous studies have successfully applied the U.S. Geological Survey’s Transient Rainfall Infiltration and Grid-Based Regional Slope-Stability (TRIGRS) model (Baum et al. 2002) to compute infiltration-driven changes in the hillslopes’ factor of safety on small scales (i.e., tens of square kilometers). Soil data input for such models are difficult to obtain across larger regions. This work describes a novel methodology for the application of TRIGRS over broad areas with relatively uniform hydrogeological properties. The study area is a 550-km2 region in Central Italy covered by post-orogenic Quaternary sediments. Due to the lack of field data, we assigned mechanical and hydrological property values through a statistical analysis based on literature review of soils matching the local lithologies. We calibrated the model using rainfall data from 25 historical rainfall events that triggered landslides. We compared the variation of pressure head and factor of safety with the landslide occurrence to identify the best fitting input conditions. Using calibrated inputs and a soil depth model, we ran TRIGRS for the study area. Receiver operating characteristic (ROC) analysis, comparing the model’s output with a shallow landslide inventory, shows that TRIGRS effectively simulated the instability conditions in the post-orogenic complex during historical rainfall scenarios. The implication of this work is that rainfall-induced landslides over large regions may be predicted by a deterministic model, even where data on geotechnical and hydraulic properties as well as temporal changes in topography or subsurface conditions are not available.

  17. Protection des cultures à l'aide de la haie morte et de la haie vive dans la région de Ségou, au Mali

    Directory of Open Access Journals (Sweden)

    Levasseur, V.

    2009-01-01

    Full Text Available Crop Protection with the Help of Dead and Live Fences in the Segou Region, in Mali. In the Segou region, in Mali, market crop production during the dry season is increasing. This type of production needs to be protected from livestock, which roams freely during the dry season. Three types of fences are used by farmers in order to protect their plots: dead fence, which is made of crop residues or branches from thorny trees and shrubs; traditional live fence, most often consisting of euphorbia planted close to one another; and improved live fence, composed of multipurpose trees and shrubs, usually thorny. A study was conducted in eleven villages in order to analyse the contribution of these different types of fences to the protection of crops, as well as some constraints related to their use. Results show that three quarters of the agricultural production units (APU use one of the crop protection techniques during the dry season. Three out of ten APU even use one type of fences or the other during the rainy season. Although the protection it offers is limited, the dead fence seems well adapted to the farmer's agrarian system. The improved live fence, for its part, faces many constraints, especially with regard to labour organization of the members of the APU.

  18. Actin-Based Motility of Burkholderia thailandensis Requires a Central Acidic Domain of BimA That Recruits and Activates the Cellular Arp2/3 Complex▿

    OpenAIRE

    Sitthidet, Chayada; Stevens, Joanne M; Field, Terence R.; Layton, Abigail N.; Korbsrisate, Sunee; Stevens, Mark P.

    2010-01-01

    Burkholderia species use BimA for intracellular actin-based motility. Uniquely, Burkholderia thailandensis BimA harbors a central and acidic (CA) domain. The CA domain was required for actin-based motility, binding to the cellular Arp2/3 complex, and Arp2/3-dependent polymerization of actin monomers. Our data reveal distinct strategies for actin-based motility among Burkholderia species.

  19. Hybrid Page Scoring Algorithm Based on Centrality and PageRank%基于中心性和PageRank的网页综合评分方法

    Institute of Scientific and Technical Information of China (English)

    乔少杰; 彭京; 李天瑞; 李红; 李太勇; 王超

    2011-01-01

    In order to score Web pages in an effective manner, a new page scoring algorithm, CentralRank, was proposed based on centrality measures, including degree, betweenness and closeness, and the PageRank algorithm. The CentralRank algorithm computes the importance of pages in Web social networks based on the centrality measures and employs the PageRank algorithm to accurately score Web pages. To verify the performance of the CentralRank algorithm, a Web crawler was developed to automatically and effectively crawl Web pages. The Web crawler contains three essential techniques, that is, Web data collection, content analysis and duplicate page detection. Experiments on real data show that the CentralRank algorithm can guarantee less time deficiency and is more exact in scoring Web pages than the centrality measures-based page ranking algorithm and the PageRank algorithm with an average improvement of 14.2% and 7.5% , respectively.%为准确、高效地对网页进行评分,提出了一种基于中心性(结点度、居间度和紧密度)和PageRank算法的网页评分方法CentralRank.它采用PageBank算法计算网页分数,借助中心性度量的方法计算页面在Web社会网络中的重要性.为了验证CentralRank的性能优势,设计了一个网页抓取器,可利用该抓取器自动、准确地下载网页信息.该网页抓取器集成了网络信息采集、页面内容分析和页面消重3项技术.基于大量真实数据的实验结果表明:CentralRank在保证网页评分时间性能的前提下,比单纯基于中心性的网页评分算法和PageBank算法更准确、有效,预测准确性分别提高约14.2%和7.5%.

  20. ’Itinéraires de la faim’ des migrants subsahariens expulsés d’Algérie au Mali Organizing survival among sub-Saharan migrants expelled from Algeria to Mali

    Directory of Open Access Journals (Sweden)

    Clara Lecadet

    2010-12-01

    Full Text Available En Algérie, l’expulsion des migrants d’origine subsaharienne vers la frontière Nord du Mali est devenue depuis le début des années 2000 un processus régulier. Rationnement alimentaire drastique dans les prisons algériennes, angoisse vitale dans les ghettos organisés en micro-communautés nationales aux abords de la frontière, leitmotiv de l’aide d’urgence : la faim constitue une caractéristique majeure de l’expérience vécue par les expulsés. Elle est à la fois une violence intime, une donnée politique, un motif d’intervention humanitaire. On parlera ainsi d’itinéraires de la faim pour appréhender le processus de l’expulsion et les parcours erratiques de l’après-expulsion : ils sont ici envisagés à la fois du point de vue du dispositif étatique algérien qui en porte la responsabilité et des contre-dispositifs précaires mis en œuvre par les expulsés pour survivre. Les expulsés auto-organisés, les associations d’expulsés, l’intervention ponctuelle des ONG, tentent en effet de faire face aux expulsions par des formes de regroupement, d’accueil et de restauration atypiques dans un contexte d’abandon et de dénuement radical.Since the beginning of the century the expulsion of sub-Saharan migrants from Algeria to the Northern Malian border has become a regular event. Hunger is the main aspect of expelled migrant life, caused by poor rations in Algerian jails, daily fear in the ghettos organized into national micro-communities on the border and the limited supply of emergency aid. Hunger is simultaneously a primal suffering, a political issue and an argument for humanitarian aid. We describe the process of expulsion and the erratic journey of migrants after deportation as itineraries of hunger. These itineraries are considered from two points of view; the state processes involved in these collective deportations and the precarious strategies invented by expelled migrants to survive. A combination

  1. Modeling and optimization of antibacterial activity of the chitosan-based hydrogel films using central composite design.

    Science.gov (United States)

    Lahooti, Behnaz; Khorram, Mohammad; Karimi, Gholamreza; Mohammadi, Aliakbar; Emami, Amir

    2016-10-01

    In the present study, hydrogel films composed of chitosan-poly(vinyl alcohol)-gelatin-thyme honey were successfully prepared by casting method, and their anti-bacterial properties were modeled and optimized. Antibacterial properties of the prepared films were analyzed by applying agar diffusion method. Staphylococcus aureus and Pseudomonas aeruginosa were tested as Gram-positive and Gram-negative bacteria, respectively. In order to obtain the composition of the film with maximum inhibition zone against both above-mentioned bacterial strains, the experiments were designed using response surface methodology based on five-level central composite design with four parameters, including concentrations of chitosan, poly(vinyl alcohol), gelatin, and honey. The results indicated that the prepared samples had good antibacterial activities against these two studied bacteria strains. Response surface method is conducted to develop mathematical models for process responses. Variance analysis on the experimental data shows that inhibition zone can be predicted effectively with quadratic models. In addition, swelling properties and rate of water vapor transmission of the prepared hydrogel films were studied. Due to the successful results, this hydrogel film has an excellent potential to be explored further as a wound healing material. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 2544-2553, 2016. PMID:27241899

  2. Determinants of Cervical Cancer Screening Uptake among Women in Ilorin, North Central Nigeria: A Community-Based Study

    Directory of Open Access Journals (Sweden)

    Ajibola Idowu

    2016-01-01

    Full Text Available Introduction. Cancer of the cervix is the leading cause of cancer deaths among women in developing countries. Screening is one of the most cost effective control strategies for the disease. This study assessed the determinants of cervical cancer screening uptake among Nigerian women. Methodology. This cross-sectional study was conducted using multistage sampling technique among 338 participants in Ilorin, North Central Nigeria. A pretested questionnaire was used for data collection and data analysis was done using SPSS version 21. Chi-square test was used for bivariate analysis while binary logistic regression was used for multivariate analysis. Statistical significance was set at p<0.05. Results. Only 8.0% of the respondents had ever been screened for cancer of the cervix. The proportion of women who had ever been screened was significantly higher among those who demonstrated positive attitude to screening (81.5%, p=0.001, respondents who were aware of the disease (100.0%, p=0.001, and those who were aware of cervical cancer screening (88.9%, p=0.001. Respondents who had negative attitude had 63% lesser odds of being screened compared to those who had positive attitudes towards screening (AOR; 0.37, 95% CI; 0.01–0.28. Conclusion. There is urgent need to improve the knowledge base and attitude of Nigerian women to enhance cervical cancer screening uptake among them.

  3. Central heating plant economic evaluation program. Volume 3. Military base weather information data management program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Lin, M.C.; Moshage, R.; Schanche, G.; Blazek, C.; Biederman, R.

    1995-01-01

    Public Law has directed the Department of Defense (DOD) to rehabilitate and convert its existing domestic power plants to burn more coal. Other Federal legislation requires DOD to use the most economic fuel for any new heating system. This five-volume report discusses the Central Heating Plant Economic Evaluation Program (CHPECON), a computer program for screening potential new and retrofit steam/power generation facilities. Volume 1 is the Technical Reference. Volume 2 is the User`s Manual. Volume 3 is the Military Base Weather Information Data Management Program. Volume 4 is the Coalfield Properties Information Data Management Program. Volume 5 is the Emission Regulations Data Management Program. CHPECON provides screening criteria to evaluate competing combustion technologies using coal, gas, or oil; detailed conceptual facility design information; budgetary facility costs; and economic measures of project acceptability including total life cycle costs and levelized cost of service. The program provides sufficient flexibility to vary critical design and operating parameters to determine project sensitivity and parametric evaluation.

  4. Controlling Aedes aegypti population as DHF vector with radiation based-sterile insect technique in Banjarnegara Regency, Central Java

    International Nuclear Information System (INIS)

    The control program of dengue hemorrhagic fever (DHF) in Indonesia is still a problem due to the incomplete integrated handling. Sterile insect technique (SIT) for Aedes aegypti as DHF vector was considered as a potential strategy for controlling the DHF. A preliminary survey was carried out to determine the characteristic of A aegypti population in the study site before the implementation of SIT. The implementation of radiation based-SIT was carried out in Krandegan and Kutabanjar Villages of Banjarnegara Regency, Central Java which involved 99 houses. One hundred gamma rays irradiated male mosquitoes were released to each house up to five times. The eggs, larvae and adult mosquitoes were collected using ovitrap and weekly observed. The initial population density of A. aegypti in the studied area was obtained to be 6 mosquitoes per house with the mean index of house was 15.86% and the mean sterility of sterilized mosquitoes was 79.16%. The SIT effectively reduced A. aegypti population after the fifth release of irradiated mosquitoes into the houses. It can be assumed that the SIT was effective in controlling DHF vector in the studied area, nevertheless, it will be more effective if it is combined with other handling techniques. (author)

  5. Conflicts over land in the Niger river delta region of Mali : exploring the usefulness of SAM and CGE models to study participatory natural resource management in agricultural and pastoral systems

    NARCIS (Netherlands)

    Kaboré, Pato Daniel

    2008-01-01

    The thesis deals with management of natural resources in the Niger Delta region of Mali. Climate changes and human activities have led to degradation of natural resources, whereas the demographic pressure increases. As a result, a social restructuring takes place: farmers are going to keep more catt

  6. Impact of Schistosoma haematobium infection on urinary tract pathology, nutritional status and anaemia in school-aged children in two different endemic areas of the Niger River Basin, Mali

    DEFF Research Database (Denmark)

    Sacko, Moussa; Magnussen, Pascal; Keita, Adama D.;

    2011-01-01

    The aim of the present study was to contribute to define urinary schistosomiasis-related morbidity indicators and to understand the relationship between infection intensity and disease burden among school-aged children in different endemic areas of Mali. A cross sectional study was undertaken in ...

  7. Ocular biometry in the adult population in rural central China: a population-based, cross-sectional study

    Institute of Scientific and Technical Information of China (English)

    Ting; Fu; Yin-Wei; Song; Zhi-Qi; Chen; Jun-Wen; He; Kun; Qiao; Xu-Fang; Sun; Hong; Zhang; Jun-Ming; Wang

    2015-01-01

    ·AIM: To describe the distribution and determinants of ocular biometric parameters and to ascertain the relative importance of these determinants in a large population of adults in rural central China.·METHODS: A population-based, cross-sectional study performed in rural central China included 1721 participants aged 40 or more years. Ocular biometrical parameters including axial length(AL), anterior chamber depth(ACD), radius of corneal curvature(K) and horizontal corneal diameter [white-to-white(WTW)distance] were measured using non-contact partial coherence interferometry [intraocular lens(IOL)-Master].·RESULTS: Ocular biometric data on 1721 participants with a average age of 57.0 ±8.7y were analyzed at last.The general mean AL, ACD, mean corneal curvature radius(MCR), WTW were 22.80±1.12, 2.96±0.36, 7.56±0.26 and 11.75 ±0.40 mm, respectively. The mean values of each parameter in 40 to 49, 50 to 59, 60 to 69, and 70 to91 years age groups were as follows: AL, 22.77 ±0.87,22.76 ±1.06, 22.89 ±1.41, 22.92 ±0.80 mm; ACD, 3.10 ±0.32,2.98 ±0.34, 2.86 ±0.36, 2.77 ±0.35 mm; MCR, 7.58 ±0.25,7.54 ±0.26, 7.55 ±0.26, 7.49 ±0.28 mm; WTW, 11.79 ±0.38,11.75 ±0.40, 11.72 ±0.41, 11.67 ±0.41 mm. The AL, ACD,MCR and WTW were correlated with age and the AL was correlated with height and weight.·CONCLUSION: Our findings can serve as an important normative reference for multiple purposes and may help to improve the quality of rural eye care.

  8. Characterisation of Central-African emissions based on MAX-DOAS measurements, satellite observations and model simulations over Bujumbura, Burundi.

    Science.gov (United States)

    Gielen, Clio; Hendrick, Francois; Pinardi, Gaia; De Smedt, Isabelle; Stavrakou, Trissevgeni; Yu, Huan; Fayt, Caroline; Hermans, Christian; Bauwens, Maité; Ndenzako, Eugene; Nzohabonayo, Pierre; Akimana, Rachel; Niyonzima, Sébastien; Müller, Jean-Francois; Van Roozendael, Michel

    2016-04-01

    Central Africa is known for its strong biogenic, pyrogenic, and to a lesser extent anthropogenic emissions. Satellite observations of species like nitrogen dioxide (NO2) and formaldehyde (HCHO), as well as inverse modelling results have shown that there are large uncertainties associated with the emissions in this region. There is thus a need for additional measurements, especially from the ground, in order to better characterise the biomass-burning and biogenic products emitted in this area. We present MAX-DOAS measurements of NO2, HCHO, and aerosols performed in Central Africa, in the city of Bujumbura, Burundi (3°S, 29°E, 850m). A MAX-DOAS instrument has been operating at this location by BIRA-IASB since late 2013. Aerosol-extinction and trace-gases vertical profiles are retrieved by applying the optimal-estimation-based profiling tool bePRO to the measured O4, NO2 and HCHO slant-column densities. The MAX-DOAS vertical columns and profiles are used for investigating the diurnal and seasonal cycles of NO2, HCHO, and aerosols. Regarding the aerosols, the retrieved AODs are compared to co-located AERONET sun photometer measurements for verification purpose, while in the case of NO2 and HCHO, the MAX-DOAS vertical columns and profiles are used for validating GOME-2 and OMI satellite observations. To characterise the biomass-burning and biogenic emissions in the Bujumbura region, the trace gases and aerosol MAX-DOAS retrievals are used in combination to MODIS fire counts/radiative-power and GOME-2/OMI NO2 and HCHO satellite data, as well as simulations from the NOAA backward trajectory model HYSPLIT. First results show that HCHO seasonal variation around local noon is driven by the alternation of rain and dry periods, the latter being associated with intense biomass-burning agricultural activities and forest fires in the south/south-east and transport from this region to Bujumbura. In contrast, NO2 is seen to depend mainly on local emissions close to the city, due

  9. Nanoparticle-based drug delivery to improve the efficacy of antiretroviral therapy in the central nervous system

    Directory of Open Access Journals (Sweden)

    Gomes MJ

    2014-04-01

    Full Text Available Maria João Gomes,1 José das Neves,1,2 Bruno Sarmento1,2 1Instituto de Engenharia Biomédica (INEB, Porto, Portugal; 2Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde (IINFACTS, Instituto Superior de Ciências da Saúde-Norte, CESPU, Gandra, Portugal Abstract: Antiretroviral drug therapy plays a cornerstone role in the treatment of human immunodeficiency virus (HIV/acquired immunodeficiency syndrome patients. Despite obvious advances over the past 3 decades, new approaches toward improved management of infected individuals are still required. Drug distribution to the central nervous system (CNS is required in order to limit and control viral infection, but the presence of natural barrier structures, in particular the blood–brain barrier, strongly limits the perfusion of anti-HIV compounds into this anatomical site. Nanotechnology-based approaches may help providing solutions for antiretroviral drug delivery to the CNS by potentially prolonging systemic drug circulation, increasing the crossing and reducing the efflux of active compounds at the blood–brain barrier, and providing cell/tissue-targeting and intracellular drug delivery. After an initial overview on the basic features of HIV infection of the CNS and barriers to active compound delivery to this anatomical site, this review focuses on recent strategies based on antiretroviral drug-loaded solid nanoparticles and drug nanosuspensions for the potential management of HIV infection of the CNS. Keywords: HIV/AIDS, blood–brain barrier, protease inhibitors, efflux transporters, drug targeting

  10. Mapping hydrological environments in central Amazonia: ground validation and surface model based on SRTM DEM data corrected for deforestation

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    G. M. Moulatlet

    2014-07-01

    Full Text Available One of the most important freely available digital elevation models (DEMs for Amazonia is the one obtained by the Shuttle Radar Topography Mission (SRTM. However, since SRTM tends to represent the vegetation surface instead of the ground surface, the broad use of SRTM DEM as a framework for terrain description in Amazonia is hampered by the presence of deforested areas. We present here two datasets: (1 a deforestation-corrected SRTM DEM for the interfluve between the Purus and Madeira rivers, in central Amazonia, which passed through a careful identification of different environments and has deforestation features corrected by a new method of increasing pixel values of the DEM; and (2 a set of eighteen hydrological-topographic descriptors based on the corrected SRTM DEM. The hydrological-topographic description was generated by the Height Above the Nearest Drainage (HAND algorithm, which normalizes the terrain elevation (a.s.l. by the elevation of the nearest hydrologically connected drainage. The validation of the HAND dataset was done by in situ hydrological description of 110 km of walking trails also available in this dataset. The new SRTM DEM expands the applicability of SRTM data for landscape modelling; and the datasets of hydrological features based on topographic modelling is undoubtedly appropriate for ecological modelling and an important contribution for environmental mapping of Amazonia. The deforestation-corrected SRTM DEM is available at http://ppbio.inpa.gov.br/knb/metacat/naman.318.3/ppbio; the polygons selected for deforestation correction are available at http://ppbio.inpa.gov.br/knb/metacat/naman.317.3/ppbio; the set of hydrological-topographic descriptors is available at http://ppbio.inpa.gov.br/knb/metacat/naman.544.2/ppbio; and the environmental description of access trails is available at http://ppbio.inpa.gov.br/knb/metacat/naman.541.2/ppbio.

  11. A GIS-based Spatial Analysis of Volcanoes in the Central Andes: Insights Into Factors Controlling Volcano Spacing.

    Science.gov (United States)

    Savant, S. S.; de Silva, S. L.

    2005-12-01

    r°S). The central part of the arc between 22 r° and 24 r°S shows the highest density of volcanoes. An interpolated continuous raster grid of volcano base elevation revealed a strong positive correlation with the density of volcanoes. Interestingly, the spacing of the peaks in density is fairly regular at about 75 to 110 km. We interpret the different orders of spacing as reflecting control by different levels within the plumbing system for the arc. The spacing of density peaks (clusters) is likely the primary spacing of diapirs rising from the source layer into the lithosphere. The dominant 10 to 30 km spacing of individual volcanoes probably reflects the influence of intra-crustal regions superimposed on the primary spacing. These regions may be mid-crustal, low-velocity, high-conductivity zones that have been imaged geophysically and/or the influence of older upper crustal batholiths that may have been emplaced into the thickest crust between 22 r° and 24 r°S.

  12. Space-time clustering of childhood malaria at the household level: a dynamic cohort in a Mali village

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    Ouattara Amed

    2006-11-01

    Full Text Available Abstract Background Spatial and temporal heterogeneities in the risk of malaria have led the WHO to recommend fine-scale stratification of the epidemiological situation, making it possible to set up actions and clinical or basic researches targeting high-risk zones. Before initiating such studies it is necessary to define local patterns of malaria transmission and infection (in time and in space in order to facilitate selection of the appropriate study population and the intervention allocation. The aim of this study was to identify, spatially and temporally, high-risk zones of malaria, at the household level (resolution of 1 to 3 m. Methods This study took place in a Malian village with hyperendemic seasonal transmission as part of Mali-Tulane Tropical Medicine Research Center (NIAID/NIH. The study design was a dynamic cohort (22 surveys, from June 1996 to June 2001 on about 1300 children (Plasmodium falciparum, P. malariae and P. ovale infection and P. falciparum gametocyte carriage by means of time series and Kulldorff's scan statistic for space-time cluster detection. Results The time series analysis determined that malaria parasitemia (primarily P. falciparum was persistently present throughout the population with the expected seasonal variability pattern and a downward temporal trend. We identified six high-risk clusters of P. falciparum infection, some of which persisted despite an overall tendency towards a decrease in risk. The first high-risk cluster of P. falciparum infection (rate ratio = 14.161 was detected from September 1996 to October 1996, in the north of the village. Conclusion This study showed that, although infection proportions tended to decrease, high-risk zones persisted in the village particularly near temporal backwaters. Analysis of this heterogeneity at the household scale by GIS methods lead to target preventive actions more accurately on the high-risk zones identified. This mapping of malaria risk makes it possible

  13. Feasibility of onchocerciasis elimination with ivermectin treatment in endemic foci in Africa: first evidence from studies in Mali and Senegal.

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    Lamine Diawara

    Full Text Available BACKGROUND: Mass treatment with ivermectin is a proven strategy for controlling onchocerciasis as a public health problem, but it is not known if it can also interrupt transmission and eliminate the parasite in endemic foci in Africa where vectors are highly efficient. A longitudinal study was undertaken in three hyperendemic foci in Mali and Senegal with 15 to 17 years of annual or six-monthly ivermectin treatment in order to assess residual levels of infection and transmission and test whether ivermectin treatment could be safely stopped in the study areas. METHODOLOGY/PRINCIPAL FINDINGS: Skin snip surveys were undertaken in 126 villages, and 17,801 people were examined. The prevalence of microfilaridermia was <1% in all three foci. A total of 157,500 blackflies were collected and analyzed for the presence of Onchocerca volvulus larvae using a specific DNA probe, and vector infectivity rates were all below 0.5 infective flies per 1,000 flies. Except for a subsection of one focus, all infection and transmission indicators were below postulated thresholds for elimination. Treatment was therefore stopped in test areas of 5 to 8 villages in each focus. Evaluations 16 to 22 months after the last treatment in the test areas involved examination of 2,283 people using the skin snip method and a DEC patch test, and analysis of 123,000 black flies. No infected persons and no infected blackflies were detected in the test areas, and vector infectivity rates in other catching points were <0.2 infective flies per 1,000. CONCLUSION/SIGNIFICANCE: This study has provided the first empirical evidence that elimination of onchocerciasis with ivermectin treatment is feasible in some endemic foci in Africa. Although further studies are needed to determine to what extent these findings can be extrapolated to other endemic areas in Africa, the principle of elimination has been established. The African Programme for Onchocerciasis Control has adopted an additional

  14. Comment on "Mutation rate and genotype variation of Ebola virus from Mali case sequences".

    Science.gov (United States)

    Rambaut, Andrew; Dudas, Gytis; de Carvalho, Luiz Max; Park, Daniel J; Yozwiak, Nathan L; Holmes, Edward C; Andersen, Kristian G

    2016-08-12

    Hoenen et al (Reports, 3 April 2015, p. 117; published online 26 March) suggested that the Ebola virus Makona responsible for the West African epidemic evolved more slowly than previously reported. We show that this was based on corrupted data. An erratum provided a rate compatible with the initial and later, more precise, estimates but did not correctly state the nature of the error. PMID:27516592

  15. Where do we go from here? Prevalence of trachoma three years after stopping mass distribution of antibiotics in the regions of Kayes and Koulikoro, Mali.

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    Sanoussi Bamani

    Full Text Available OBJECTIVES: A national survey in 1997 demonstrated that trachoma was endemic in Mali. Interventions to control trachoma including mass drug administration (MDA with azithromycin were launched in the regions of Kayes and Koulikoro in 2003. MDA was discontinued after three annual rounds in 2006, and an impact survey conducted. We resurveyed all districts in Kayes and Koulikoro in 2009 to reassess trachoma prevalence and determine intervention objectives for the future. In this paper we present findings from both the 2006 and 2009 surveys. METHODS: Population-based cluster surveys were conducted in each of the nine districts in Koulikoro in 2006 and 2009, whilst in Kayes, four of seven districts in 2006 and all seven districts in 2009 were surveyed. Household members present were examined for clinical signs of trachoma. RESULTS: Overall, 29,179 persons from 2,528 compounds, in 260 clusters were examined in 2006 and 32,918 from 7,533 households in 320 clusters in 2009. The prevalence of TF in children aged 1-9 years in Kayes and Koulikoro was 3.9% (95%CI 2.9-5.0%, range by district 1.2-5.4% and 2.7% (95%CI 2.3-3.1%, range by district 0.1-5.0% respectively in 2006. In 2009 TF prevalence was 7.26% (95%CI 6.2-8.2%, range by district 2.5-15.4% in Kayes and 8.19% (95%CI 7.3-9.1%, range by district 1.7-17.2% in Koulikoro among children of the same age group. TT in adults 15 years of age and older was 2.37% (95%CI 1.66-3.07%, range by district 0.30-3.54% in 2006 and 1.37% (95%CI 1.02-1.72%, range by district 0.37-1.87% in 2009 in Kayes and 1.75% (95%CI 1.31-2.23%, range by district 1.06-2.49% in 2006 and 1.08% (95%CI 0.86-1.30%, range by district 0.34-1.78% in 2009 in Koulikoro. CONCLUSIONS: Using WHO guidelines for decision making, four districts, Bafoulabe in Kayes Region; and Banamba, Kolokani and Koulikoro in Koulikoro Region, still meet criteria for district-wide implementation of the full SAFE strategy as TF in children exceeds 10%. A community

  16. Lengths of the maxillary central incisor, the nasal bone, and the anterior cranial base in different skeletal malocclusions

    DEFF Research Database (Denmark)

    Arntsen, Torill; Kjær, Inger; Sonnesen, Liselotte

    2009-01-01

    with neutral occlusion and normal craniofacial morphology (n=39). Two-way ANOVA tests were used to evaluate differences in lengths between groups and gender. Results. Statistically shorter maxillary central incisor length was found in the open bite group (p

  17. Phylogenetic relationships between telmatobiinids (Anura, Ceratophryidae, Telmatobiinae) of central Andes based on morphology of larval and adult stages

    OpenAIRE

    César Aguilar; Niels Valencia

    2011-01-01

    Batrachophrynus and Telmatobius are the two genus of Telmatobiinae from the central Andes. Both genera have species with adaptations for life at high altitude in the Andes, with aquatic or semi-aquatic habits in creeks, lagoons and lakes. The objective of this study is to evaluate the phylogenetic relationships between Batrachophrynus and 13 species of Telmatobius from the central Andes using larval and adult morphology including diagnostic characters for Batrachophrynus and Telmatobius, and ...

  18. Technical support by Solthis for health-care workers in order to decentralise medical treatment for people living with HIV in the Ségou region of Mali

    Directory of Open Access Journals (Sweden)

    A. Akonde

    2009-01-01

    Full Text Available Medical treatment for people living with HIV/AIDS started in Mali as early as 1997 thanks to civil society. The national response was officialised by the adoption of the Malian Initiative for Access to Antiretroviral Therapy (Initiative Malienne d’Accès aux Antirétroviraux IMAARV. In 2004 ART, drugs against opportunistic infections and basic biological monitoring were made available free of charge by decree. In 2005, decentralisation of health-care to regions and circles became one of the main thrusts of the national strategy for the fight against the pandemic. Sub-Saharan African countries are making significant efforts to provide full geographical coverage of their national territory.It is in this “scaling-up” context that the Solthis NGO (Solidarité Thérapeutique et Initiatives contre le Sida began cooperating with Malian actors to extend access to quality treatment for patients living with HIV/AIDS in the city and region of Ségou. Based on a developmental approach, Solthis opted for continuing in situ technical support for national actors in the fight against AIDS. Thanks to the daily presence of a team “in the field” Solthis devotes a large part of its activities to capacity-building for health-care workers through an exchange of medical and scientific expertise. Efforts were also made to improve health-care workers’ working conditions and to make various tests and drugs accessible to patients infected with HIV. The initial aim was to encourage universal access to ART. Today, the Ségou programme supported by Solthis has developed over 1,500 new treatments in the region. In addition, every PMTCT centre in the region offers prevention and treatment services to mothers and children. Today, the Ségou region is an integral part of the IMAARV initiative as a decentralisation pilot project.Le traitement médical des malades atteints du VIH/SIDA a débuté au Mali dès 1997 grâce à la société civile. La r

  19. Neuroarchitecture and neuroanatomy of the Drosophila central complex: A GAL4-based dissection of protocerebral bridge neurons and circuits.

    Science.gov (United States)

    Wolff, Tanya; Iyer, Nirmala A; Rubin, Gerald M

    2015-05-01

    Insects exhibit an elaborate repertoire of behaviors in response to environmental stimuli. The central complex plays a key role in combining various modalities of sensory information with an insect's internal state and past experience to select appropriate responses. Progress has been made in understanding the broad spectrum of outputs from the central complex neuropils and circuits involved in numerous behaviors. Many resident neurons have also been identified. However, the specific roles of these intricate structures and the functional connections between them remain largely obscure. Significant gains rely on obtaining a comprehensive catalog of the neurons and associated GAL4 lines that arborize within these brain regions, and on mapping neuronal pathways connecting these structures. To this end, small populations of neurons in the Drosophila melanogaster central complex were stochastically labeled using the multicolor flip-out technique and a catalog was created of the neurons, their morphologies, trajectories, relative arrangements, and corresponding GAL4 lines. This report focuses on one structure of the central complex, the protocerebral bridge, and identifies just 17 morphologically distinct cell types that arborize in this structure. This work also provides new insights into the anatomical structure of the four components of the central complex and its accessory neuropils. Most strikingly, we found that the protocerebral bridge contains 18 glomeruli, not 16, as previously believed. Revised wiring diagrams that take into account this updated architectural design are presented. This updated map of the Drosophila central complex will facilitate a deeper behavioral and physiological dissection of this sophisticated set of structures. PMID:25380328

  20. Structure-based functional characterization of repressor of toxin (Rot), a central regulator of Staphylococcus aureus virulence.

    Science.gov (United States)

    Killikelly, April; Benson, Meredith A; Ohneck, Elizabeth A; Sampson, Jared M; Jakoncic, Jean; Spurrier, Brett; Torres, Victor J; Kong, Xiang-Peng

    2015-01-01

    Staphylococcus aureus is responsible for a large number of diverse infections worldwide. In order to support its pathogenic lifestyle, S. aureus has to regulate the expression of virulence factors in a coordinated fashion. One of the central regulators of the S. aureus virulence regulatory networks is the transcription factor repressor of toxin (Rot). Rot plays a key role in regulating S. aureus virulence through activation or repression of promoters that control expression of a large number of critical virulence factors. However, the mechanism by which Rot mediates gene regulation has remained elusive. Here, we have determined the crystal structure of Rot and used this information to probe the contribution made by specific residues to Rot function. Rot was found to form a dimer, with each monomer harboring a winged helix-turn-helix (WHTH) DNA-binding motif. Despite an overall acidic pI, the asymmetric electrostatic charge profile suggests that Rot can orient the WHTH domain to bind DNA. Structure-based site-directed mutagenesis studies demonstrated that R(91), at the tip of the wing, plays an important role in DNA binding, likely through interaction with the minor groove. We also found that Y(66), predicted to bind within the major groove, contributes to Rot interaction with target promoters. Evaluation of Rot binding to different activated and repressed promoters revealed that certain mutations on Rot exhibit promoter-specific effects, suggesting for the first time that Rot differentially interacts with target promoters. This work provides insight into a precise mechanism by which Rot controls virulence factor regulation in S. aureus.

  1. A Review of a Successful Unsubsidized Market-Based Rural Solar Development Initiative in Laikipia District, Central Kenya

    Directory of Open Access Journals (Sweden)

    O. Wambuguh

    2013-10-01

    Full Text Available The development of renewable energy technologies (RETs in many areas far from grid-based electricity have primarily involved solar photovoltaics (SPVs which tap solar radiation to provide heat, light, hot water, electricity, and cooling for homes, businesses, and industry. A study on RETs took place in the Wiyumiririe Location of Laikipia District (north-central Kenya, a rich agricultural region. To explore this solar initiative in such a remote part of the country, a purposive randomized convenience sample of 246 households was selected and landowner interviews conducted, followed by field visits and observations. Although more than half of the households visited had SPV installations, solar energy was found to contribute only 18% of household estimated total energy needs; most residents still primarily relying on traditional energy sources. Several types of solar panels of different capacities and costs were utilized. Many landowners had at least one or two rooms using solar energy for household lighting, for appliance charging and to power radio and television. Almost all respondents appreciated that solar energy was clean renewable energy that greatly improved household living conditions; gave them some prestige; was easy to use and maintain; and was available year around. Although such significant benefits were associated with SPVs, only about 40% of residents interviewed were somehow satisfied with its development. Respondents expressed specific developmental initiatives that were closely associated with the availability of solar energy. Nevertheless, a number of challenges were raised associated with SPVs primarily investment capital and equipment costs and maintenance. As solutions to capital building will not solely rely on subsidies or individual farmer inputs, strategies must be found to mobilize the essential and tested tools for success including sustainable capital generation, building local institutions and capacities that

  2. FLUID DYNAMICS PROCESSES AT THE CENTRAL SAKHALIN FAULT (BASED ON OBSERVATIONS OF THE YUZHNO-SAKHALINSK MUD VOLCANO

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    Valery V. Ershov

    2015-10-01

    Full Text Available The Yuzhno-Sakhalinsk mud volcano is located in the southern part of the Sakhalin Island within the area of the Central Sakhalin fault, one of the largest disjunctive dislocations of the island. The volcano was monitored during field seasons in the period from 2005 to 2007, and data on flow rates, chemical and isotope compositions of gases, temperature and chemical composition of watermud mixture in the volcano’s blowouts were collected and analysed. During the observation period, seismic activity in the region under study was significantly variable in time and space. The monitoring results revealed «traces» of two earthquakes in the blowout activity of the Yuzhno-Sakhalinsk mud volcano – the Gornazavodsk earthquake, that took place on 17 (18 August 2006, and the Nevelsk earthquake of 2 August 2007. Based on results of our analyses of the field data and mathematical simulation data, it is possible to conclude that an additional inflow of «deep geofluids» could not have been a major trigger of the activity of the volcano after the earthquakes. In our opinion, all the observed anomalies may result from «water – rock – gas» interactions in the top part of the mud volcano’s feeder channel. A combination of water and gas flows in the volcano’s channel and silica-alumina rocks comprises a specific geochemical system that is sensitive to external (seismic impacts. Therefore, comprehensive consideration of physical and chemical processes within fluid-dynamic systems is required for assurance of correct interpretation of empirical data.

  3. Field based measurements of albedo for two candidate perennial cellulosic feedstocks and row crops in Central Illinois

    Science.gov (United States)

    Miller, J. N.; VanLoocke, A.; Bernacchi, C. J.

    2012-12-01

    The production of perennial cellulosic feedstocks for bioenergy present the potential to diversify regional economies and the national energy supply, while also serving as a climate 'regulators' due to a number of biogeochemical and biophysical differences relative to row crops. Numerous observationally and modeling based approaches, including life cycle analyses have investigated biogeochemical tradeoffs, such as increased carbon sequestration and biophysical increased water use, associated with growing cellulosic feedstocks. A less understood aspect is the biophysical changes associated with the difference in albedo, which will alter the local energy balance and could cause a local to regional cooling several times larger than that associated with offsetting carbon. To address this factor an experiment consisting of paired fields of Miscanthus and Switchgrass, two of the leading perennial cellulosic feedstock candidates, and traditional row crops was established in central Illinois. Data from the first two growing seasons indicate that this effect is most pronounced during the spring and fall as perennial biofuel crops green up earlier and senesce later than common annual row crops. The albedo of the perennials converges to that of the row crops during the growing season as the canopies develop. During the early winter, before the perennial crops are harvested, the albedo over fallow soybean and maize fields can vary greatly depending on snowfall and, to a lesser extent, soil moisture, whereas perennials show less variation. Thus, perennial biofuel crops also have the potential to buffer the local environment against short-term variations in climate. These factors should be considered when evaluating the tradeoffs and climate-regulation services associated with large-scale planting of bioenergy crops.

  4. Central metabolic responses to the overproduction of fatty acids in Escherichia coli based on 13C-metabolic flux analysis.

    Science.gov (United States)

    He, Lian; Xiao, Yi; Gebreselassie, Nikodimos; Zhang, Fuzhong; Antoniewiez, Maciek R; Tang, Yinjie J; Peng, Lifeng

    2014-03-01

    We engineered a fatty acid overproducing Escherichia coli strain through overexpressing tesA (“pull”) and fadR (“push”) and knocking out fadE (“block”). This “pull-push-block” strategy yielded 0.17 g of fatty acids (C12–C18) per gram of glucose (equivalent to 48% of the maximum theoretical yield) in batch cultures during the exponential growth phase under aerobic conditions. Metabolic fluxes were determined for the engineered E. coli and its control strain using tracer ([1,2-13C]glucose) experiments and 13C-metabolic flux analysis. Cofactor (NADPH) and energy (ATP) balances were also investigated for both strains based on estimated fluxes. Compared to the control strain, fatty acid overproduction led to significant metabolic responses in the central metabolism: (1) Acetic acid secretion flux decreased 10-fold; (2) Pentose phosphate pathway and Entner–Doudoroff pathway fluxes increased 1.5- and 2.0-fold, respectively; (3) Biomass synthesis flux was reduced 1.9-fold; (4) Anaplerotic phosphoenolpyruvate carboxylation flux decreased 1.7-fold; (5) Transhydrogenation flux converting NADH to NADPH increased by 1.7-fold. Real-time quantitative RT-PCR analysis revealed the engineered strain increased the transcription levels of pntA (encoding the membrane-bound transhydrogenase) by 2.1-fold and udhA (encoding the soluble transhydrogenase) by 1.4-fold, which is in agreement with the increased transhydrogenation flux. Cofactor and energy balances analyses showed that the fatty acid overproducing E. coli consumed significantly higher cellular maintenance energy than the control strain. We discussed the strategies to future strain development and process improvements for fatty acid production in E. coli.

  5. Variability of floods, droughts and windstorms over the past 500 years in Central Europe based on documentary and instrumental data

    Science.gov (United States)

    Brazdil, Rudolf

    2016-04-01

    Hydrological and meteorological extremes (HMEs) in Central Europe during the past 500 years can be reconstructed based on instrumental and documentary data. Documentary data about weather and related phenomena represent the basic source of information for historical climatology and hydrology, dealing with reconstruction of past climate and HMEs, their perception and impacts on human society. The paper presents the basic distribution of documentary data on (i) direct descriptions of HMEs and their proxies on the one hand and on (ii) individual and institutional data sources on the other. Several groups of documentary evidence such as narrative written records (annals, chronicles, memoirs), visual daily weather records, official and personal correspondence, special prints, financial and economic records (with particular attention to taxation data), newspapers, pictorial documentation, chronograms, epigraphic data, early instrumental observations, early scientific papers and communications are demonstrated with respect to extraction of information about HMEs, which concerns usually of their occurrence, severity, seasonality, meteorological causes, perception and human impacts. The paper further presents the analysis of 500-year variability of floods, droughts and windstorms on the base of series, created by combination of documentary and instrumental data. Results, advantages and drawbacks of such approach are documented on the examples from the Czech Lands. The analysis of floods concentrates on the River Vltava (Prague) and the River Elbe (Děčín) which show the highest frequency of floods occurring in the 19th century (mainly of winter synoptic type) and in the second half of the 16th century (summer synoptic type). Reported are also the most disastrous floods (August 1501, March and August 1598, February 1655, June 1675, February 1784, March 1845, February 1862, September 1890, August 2002) and the European context of floods in the severe winter 1783/84. Drought

  6. Effect of Direct Seeding Mulch-Based Systems on Soil Carbon Storage and Macrofauna in Central Brazil

    Directory of Open Access Journals (Sweden)

    Eric Blanchart

    2007-03-01

    Full Text Available Soils represent a large carbon pool, approximately 1500 Gt, equivalent to almost three times the quantity stored in terrestrial biomass and twice the amount stored in the atmosphere. Any modification of land-use or land management can induce variations in soil carbon stocks, even in agricultural systems that are perceived to be in a steady state. These modifications also alter soil macrofauna that is known to affect soil carbon dynamics. Direct seeding Mulch-based Cropping (DMC systems with two crops per year without soil tillage have widely been adopted over the last 10 to 15 years in the Cerrado (central region of Brazil. They are replacing the traditional soybean monocropping with fallow under conventional tillage (CT. The objective of this study was to examine how DMC practices affect soil organic carbon (SOC dynamics and macrofauna (Rio Verde, Goias State. The approach was to determine soil C stocks and macrofauna in five fields under DMC aged 1, 5, 7, 11 and 13 years. In order to compare DMC systems with the native system of the region and previous land-use, a situation under native Cerrado (tree-savanna like vegetation and a field conducted traditionally (CT were also studied. Soil C stocks were calculated for the 0-10 and 0-40 cm soil depth and also for the first 400 kg m-2 of soil to compare the same amount of soil and to suppress the potential artefact of soil compaction when sample is based on fix layer depth. Soil macrofauna was hand-sorted from soil monoliths (30 cm depth, TSBF method. In our study, the annual rate of carbon storage was equal to ca. 1.6 MgC ha-1, which is in the range of values measured for DMC in different areas of Brazil, i.e., 0.4 to 1.7 MgC ha-1 with the highest rates obtained in the Cerrado region. Compared to natural vegetation, soil macrofauna in cropped systems was strongly modified. In CT, biomass and density were very low and much lower than in DMC systems. With increasing age of DMC, total macrofauna

  7. [Cervico-facial cellulitis during pregnancy: about a series of 10 cases in Mali].

    Science.gov (United States)

    Doumbia-Singare, K; Timbo, S K; Keita, M; Ag Mohamed, A; Guindo, B; Soumaoro, S

    2014-12-01

    The objective of this work was to analyze the predisposing factors, diagnostic and therapeutic aspects of cervico-facial cellulitis on pregnancies and to determine maternal-fetal prognosis. We conducted a longitudinal observational descriptive study from January 2011 to March 2013 including records from pregnant women with cervicofacial cellulitis treated at the Oto-Rhino-Laryngology (ORL) and cervico-facial surgery department at Gabriel Touré Hospital in Bamako. Ten women met our inclusion criteria. The median age was 23 years. The entry way was dental in all cases. Three women had taken antibiotics and 3 others antibiotics associated with non steroidal anti-inflammatory. The medico-surgical treatment had permitted to cure 8 cases. Two cases of death were recorded and 4 cases of stillbirths. The cervico-facial cellulitis during pregnancy is a serious pathology that can be life-threatening to the mother and or child. Prevention is based on the control of dental status and informing women about the importance of dental hygiene. PMID:25304000

  8. Mitjans de comunicació i educació intercultural en contextos plurilingües. A proposit de Mali Media and intercultural education in multilingual contexts. About Mali Medios de comunicación y educación intercultural en contextos

    Directory of Open Access Journals (Sweden)

    Antonio M. Bañón Hernández

    2009-01-01

    Full Text Available L’educació intercultural en contextos plurilingües és un repte permanent per a totes les societats, especialment per aquelles que pretenen aconseguir ciutadans i ciutadanes que percebin la connexió entre cultures com una decidida aposta a favor de la convivència. Els mitjans tenen la seva quota de responsabilitat en aquest assumpte; una responsabilitat, això a part, que no convé sobredimensionar, però tampoc infravalorar. En aquest article reflexionem sobre aquestes qüestions prenent com a exemple el (desconeixement que, en general, hi ha sobre Mali. ____________________________________ L’éducation interculturelle dans des contextes plurilingues est un défi permanent pour toutes les sociétés, et tout particulièrement pour celles qui prétendent obtenir des citoyens et des citoyennes qu’ils/elles perçoivent la connexion entre les cultures comme un pari clair en faveur de la coexistence. Or, les moyens de communication ont leur part de responsabilité dans cette affaire; une responsabilité, cependant, qu’il ne convient pas de sur-dimensionner mais pas non plus de sous-évaluer. Dans cette article, nous réfléchissons sur ces questions en prenant comme exemple la (méconnaissance que l’on a, en général, du Mali.Intercultural education in multilingual contexts is a constant challenge for all societies,and especially for those that aim to educating citizens to understand the connection between cultures in terms of coexistence. Media have their own responsibilities in this matter, which should be neither overrated nor underrated. This paper reflects on these issues using as an example our knowledge (or lack of it about Mali.La educación intercultural en contextos plurilingües es un reto permanente para todas las sociedades, especialmente para aquellas que pretenden conseguir ciudadanos que perciban la conexión entre culturas como una decidida apuesta a favor de la convivencia. Los medios tienen su cuota de

  9. GIS-based landslide susceptibility mapping models applied to natural and urban planning in Trikala, Central Greece

    Directory of Open Access Journals (Sweden)

    Skilodimou, H. D.

    2009-06-01

    Full Text Available Landslide susceptibility mapping is a practical tool in natural and urban planning; it can be applied for determining land use zones, in construction design and planning of a variety of projects. In this study, two different GIS based landslide susceptibility maps were generated in the mountainous part of the Trikala Prefecture in Thessaly, Central Greece. This was accomplished by using different methods for correlating factors, which have an effect on landslide occurrences. The instability factors taken into account were: lithology, tectonic features, slope gradients, road network, drainage network, land use and rainfall. A frequency distribution of the half number of the landslide events of the study area in each class of the instability factors was performed in order to rate the classes. Two models have been used to combine the instability factors and assess the overall landslide susceptibility, namely: the Weight Factor Model (WeF, which is a statistical method, and the Multiple Factor Model (MuF that is a logical method. The produced maps were classified into four zones: Low, Moderate, High and Very High susceptible zones and validated using the other half number of the landslide events of the area. Evaluation of the results is optimized through a Landslide Models Indicator (La.M.I..Los mapas de susceptibilidad de deslizamientos representan una práctica herramienta en la planificación urbana y de espacios naturales. Así, puede aplicarse a la determinación de los usos de terrenos, en el diseño de construcción civil y para la planificación de gran variedad de actividades. En este estudio se generaron dos tipos diferentes de mapas de susceptibilidad basados en GIS para la parte montañosa de la prefectura de Trikala en Tesalia (Grecia Central. Estos se llevaron a cabo usando dos métodos de correlación de los factores que pueden tener un efecto en la generación de deslizamientos. Los factores de desestabilización tenidos en cuenta

  10. Livestock in the rice-based economy of Office du Niger: The development potential for increased crop–livestock integration through multi-actor processes

    NARCIS (Netherlands)

    Doumbia, D.; Paassen, van A.; Oosting, S.J.; Zijpp, van der A.J.

    2012-01-01

    A diagnostic study of the development potential of livestock for the rice-based economy of the Office du Niger (ON) was conducted in Mali. The functioning of selected farming systems and value chains were studied by means of interviews, surveys and farmer group discussions. The findings show that in

  11. Organizational centralization in radiology.

    Science.gov (United States)

    Aas, I H Monrad

    2006-01-01

    Traditionally, hospitals have a radiology department, where images are taken and interpretation occurs. Teleradiology makes it possible to capture images in one location and transmit them elsewhere for interpretation. Organizational centralization of radiology interpretations is therefore of interest. Empirical data have been collected in qualitative interviews of 26 resource persons with substantial experience with picture archiving and communication systems and teleradiology, from 12 departments of radiology in Norway. The response rate was 90%. A total of 21 theoretically possible types of centralization of image interpretation were identified, representing combinations of three categories of geographical centralization, and seven categories of centralization according to function. Various advantages and disadvantages of centralization were identified. Organizational changes may be decisive for the future of teleradiology, but it may be wise to plan for change in small steps, since we know little about how broad future organizational changes based on teleradiology will be, or what will decide how far particular organizations will go. PMID:16438776

  12. Migrants’ food habits when returning home (in Bamako, Mali, and Dakar, Senegal Pratiques alimentaires des migrants de retour au pays (Bamako et Dakar : être ou ne pas être le modèle ?

    Directory of Open Access Journals (Sweden)

    Isabelle Techoueyres

    2011-06-01

    Full Text Available This article is based on lengthy interviews with migrants from Senegal and Mali who have settled in Bordeaux, Angers and Paris from various geographic, cultural, ethnic backgrounds and socio-professional situations. Instead of questioning the link between « food and migration » in the usual way by focusing on migrants food « adaptation » in the country where they have settled, we chose to study what happens when they go back to their country of origin. The aim of this article is to present the permanence and changes or, taking up Roger Bastide’s terminology: continuity/discontinuity and discontinuity/ continuity playing a part in food habits, and the idea of ‘eating well’ among “immigrants” when they go back to their country of departure for vacation or retirement. Far from demonstrating the existence of an « original African food culture », this article rather highlights the permanent processes of food culturation taking place among both migrant and sedentary groups, while taking into account the structural constraints existing at national and global levels. Both Malian and Senegalese migrations reveal tactics used to produce alternately identity and otherness in a globalised context, but also according to different local situations.Cet article s'appuie sur une enquête auprès d’une quarantaine de « Sénégalais » et « Maliens » installés à Bordeaux, Angers ou Paris depuis les années 1960 et après, aux profils sociologiques variés (âge, origine géographique, sentiment d’appartenance ethnique, situation socio-économique et professionnelle. Nous interrogeons le lien entre « alimentation et migration » du point de vue des « retours » au pays de départ pour des vacances ou la retraite. Il s'agit de présenter les « continuités/ discontinuités » et « discontinuités/ continuités » (Bastide qui jouent un rôle dans les habitudes alimentaires, et la notion de « bien manger » parmi les

  13. Environnements économique et éducatif des ménages et échec scolaire des enfants au Mali

    OpenAIRE

    BOUARÉ Issa; KUEPIE Mathias; MISANGUMUKINI Nicaise

    2010-01-01

    Dans le cadre de cette étude, nous nous intéressons aux déterminants familiaux économique et culturels de l?échec scolaire primaire au Mali. Pour ce faire, nous mobilisons les données de l?enquête ELIM-2006 qui dispose d'un module sur les dépenses et la consommation permettant de mesurer avec finesse le niveau économique des ménages. Les analyses économétriques montrent que le capital culturel (mesuré par le niveau d'éducation moyens des adultes du ménage) a un effet bien plus important sur l...

  14. Spatial Analysis of the Central Place System Based on Accessibility%基于可达性的中心地体系的空间分析

    Institute of Scientific and Technical Information of China (English)

    张莉; 陆玉麒

    2013-01-01

    以克里斯泰勒的中心地理论为基础,以最短通行时间、加权平均出行时间作为可达性的评价指标,以基于GIS平台开发的可达性计算模块为技术支撑,从空间可达性、空间相互作用、空间服务范围几个方面对均质背景和交通背景下的中心地体系进彳空间分析,探讨中心地体系的空间演化及空间重构,以期对中心地体系的过程模拟和空间表达进行初步探索性的尝试.结果表明:均质背景下,次一级中心地产生于上一级中心地可达时间最长的地方;基于加权平均出行时间的可达性在同等级的中心地间出现了差异,相同等级的中心地越是靠近高等级中心地,其加权平均出行时间越短,由于中心地相对区位的不同,同一等级的中心地之间出现了差异增长,其结果会形成连续的中心地等级.伴随着交通网络的演进,中心地空间结构进入由“点-轴-网”构成的全面有组织的均衡发展阶段.%Based on the central place theory proposed by Walter Christaller,taking the shortest time and weighted average travel time as the accessibility evaluation index,using the accessibility calculation module as technical support based on the GIS platform,the spatial evolution and reconstruction of the central place system are explored from the aspects of spatial accessibility,spatial interactions,spatial scope of services under homogeneous background and transportation background.Through this way,formation process simulation and spatial expression of central place system are probed preliminary.The result shows that:Firstly,the secondary central place appears in the area which accessibility time is longest to the superior center under homogeneous background.Under the assumption of homogeneous plain,traffic in any direction are the same.The central place appears in the center of the hexagonal market area which accessibility is best and then present the concentric circles diffusion

  15. Adapting to climate variability and change: experiences from cereal-based farming in the central rift and Kobo Valleys, Ethiopia.

    Science.gov (United States)

    Kassie, Belay Tseganeh; Hengsdijk, Huib; Rötter, Reimund; Kahiluoto, Helena; Asseng, Senthold; Van Ittersum, Martin

    2013-11-01

    Small-holder farmers in Ethiopia are facing several climate related hazards, in particular highly variable rainfall with severe droughts which can have devastating effects on their livelihoods. Projected changes in climate are expected to aggravate the existing challenges. This study examines farmer perceptions on current climate variability and long-term changes, current adaptive strategies, and potential barriers for successful further adaptation in two case study regions-the Central Rift Valley (CRV) and Kobo Valley. The study was based on a household questionnaire, interviews with key stakeholders, and focus group discussions. The result revealed that about 99 % of the respondents at the CRV and 96 % at the Kobo Valley perceived an increase in temperature and 94 % at CRV and 91 % at the Kobo Valley perceived a decrease in rainfall over the last 20-30 years. Inter-annual and intraseasonal rainfall variability also has increased according to the farmers. The observed climate data (1977-2009) also showed an increasing trend in temperature and high inter-annual and intra-seasonal rainfall variability. In contrast to farmers' perceptions of a decrease in rainfall totals, observed rainfall data showed no statistically significant decline. The interaction among various bio-physical and socio-economic factors, changes in rainfall intensity and reduced water available to crops due to increased hot spells, may have influenced the perception of farmers with respect to rainfall trends. In recent decades, farmers in both the CRV and Kobo have changed farming practices to adapt to perceived climate change and variability, for example, through crop and variety choice, adjustment of cropping calendar, and in situ moisture conservation. These relatively low-cost changes in farm practices were within the limited adaptation capacity of farmers, which may be insufficient to deal with the impacts of future climate change. Anticipated climate change is expected to impose new

  16. Adapting to Climate Variability and Change: Experiences from Cereal-Based Farming in the Central Rift and Kobo Valleys, Ethiopia

    Science.gov (United States)

    Kassie, Belay Tseganeh; Hengsdijk, Huib; Rötter, Reimund; Kahiluoto, Helena; Asseng, Senthold; Van Ittersum, Martin

    2013-11-01

    Small-holder farmers in Ethiopia are facing several climate related hazards, in particular highly variable rainfall with severe droughts which can have devastating effects on their livelihoods. Projected changes in climate are expected to aggravate the existing challenges. This study examines farmer perceptions on current climate variability and long-term changes, current adaptive strategies, and potential barriers for successful further adaptation in two case study regions—the Central Rift Valley (CRV) and Kobo Valley. The study was based on a household questionnaire, interviews with key stakeholders, and focus group discussions. The result revealed that about 99 % of the respondents at the CRV and 96 % at the Kobo Valley perceived an increase in temperature and 94 % at CRV and 91 % at the Kobo Valley perceived a decrease in rainfall over the last 20-30 years. Inter-annual and intraseasonal rainfall variability also has increased according to the farmers. The observed climate data (1977-2009) also showed an increasing trend in temperature and high inter-annual and intra-seasonal rainfall variability. In contrast to farmers’ perceptions of a decrease in rainfall totals, observed rainfall data showed no statistically significant decline. The interaction among various bio-physical and socio-economic factors, changes in rainfall intensity and reduced water available to crops due to increased hot spells, may have influenced the perception of farmers with respect to rainfall trends. In recent decades, farmers in both the CRV and Kobo have changed farming practices to adapt to perceived climate change and variability, for example, through crop and variety choice, adjustment of cropping calendar, and in situ moisture conservation. These relatively low-cost changes in farm practices were within the limited adaptation capacity of farmers, which may be insufficient to deal with the impacts of future climate change. Anticipated climate change is expected to impose new

  17. Constraining the magma flow record based on magmatic and magnetic data in La Gloria Pluton, central Chile

    Science.gov (United States)

    Gutierrez, F. J.; Payacán, I.; Gelman, S. E.; Bachmann, O.; Creative Physical Petrology Team

    2013-05-01

    The magmatic origin of the anisotropy of magnetic susceptibility (AMS) is examined in comparison with magmatic anisotropy data in a small, shallow, silicic magma reservoir in the upper crust. La Gloria Pluton (LGP) is a 10 Ma granodiorite/quartz monzonite of about 250 km3 located in the southern Andes, central Chile. LGP represents a particularly simple case of a silicic intrusion that was assembled in only a few pulses and cooled over a short time interval. Hornblende, biotite and minor magnetite are ubiquitous mafic phases. The AMS tensor indicates that magnetic fabric has an oblate shape (i.e. magnetic foliation is higher than magnetic lineation). Lineations are weak (values up to 1.05), have a N-NW trend with a nearly horizontal dip and are interpreted to represent axisymmetric convection parallel to the main pluton elongation. Foliations are more pronounced (values up to 1.14), having NW trends and dips that vary gradually from vertical at the walls, to horizontal at the center and near the roof of the chamber. We selected 12 samples from AMS sites to obtain petrographic data (well-distributed throughout the pluton, containing samples from the walls, the center and the roof of LGP), and then, determine the magmatic fabric (anisotropy, lineation, foliation). We made 3 oriented thin sections per sample oriented with the AMS. Magmatic anisotropy data were obtained by measuring mineral length, width and orientation in photomicrographs of the three main planes of the AMS tensor, producing 3-D mineral data which were collected for plagioclase and amphibole + bitotite independently. For each site, a Bingham distribution with 95% of confidence is used to determine the mean mineral orientations and their angle difference with the AMS axes. Magmatic anisotropy tensor and rotations with respect to the AMS tensor are determined using both eigenvalues and minimization algorithms. Preliminary results indicate that crystals are coherently oriented in both mineral groups, and

  18. [Vectorial transmission of malaria in a village along the Niger River and its fishing hamlet (Kéniéroba and Fourda, Mali)].

    Science.gov (United States)

    Keïta, M; Baber, I; Sogoba, N; Maïga, H M; Diallo, M'b; Doumbia, S; Traoré, S F

    2014-12-01

    A better understanding of malaria transmission dynamics is an essential element in the development of any targeted vector control strategy. The objective of this study was to better understand malaria transmission dynamics along the Niger River in Sudan savanna zone of Mali. Trough cross-sectional surveys, Anopheline larvae were collected by WHO standard dipping technique, and vector adults by Human Landing and pyrethrum spray catches methods. The vector population was composed of An. gambiae s.l. (> 99%) and An. funestus (hamlet Fourda) compared to farther inland Kéniéroba. The average infection rate of An. gambiae s.l. was 3.63% and 4.06% in Kéniéroba and Fourda respectively. The average entomological inoculation rate (EIR) during the study period was almost similar in Kéniéroba (0.70 infective bites/person/month) and Fourda (0.69 infective bites/person/month). The means EIRs over each of the rainy season 2006 and 2007 were always higher than the one of the dry season 2007 in both localities, with much smaller amplitude in Fourda than in Kéniéroba. However, the level of the transmission was 2.31 (0.37/0.16) times higher in Fourda than in Kéniéroba during the dry season.We conclude that in Sudan savanna zone of Mali, malaria transmission along the river is continuous throughout the year, but it is more intense in the immediate vicinity of the river during the dry season than during the rainy season in opposition to more distant localities to the river and vector control should not be focused only on the rainy in such setting. PMID:25326713

  19. [Vectorial transmission of malaria in a village along the Niger River and its fishing hamlet (Kéniéroba and Fourda, Mali)].

    Science.gov (United States)

    Keïta, M; Baber, I; Sogoba, N; Maïga, H M; Diallo, M'b; Doumbia, S; Traoré, S F

    2014-12-01

    A better understanding of malaria transmission dynamics is an essential element in the development of any targeted vector control strategy. The objective of this study was to better understand malaria transmission dynamics along the Niger River in Sudan savanna zone of Mali. Trough cross-sectional surveys, Anopheline larvae were collected by WHO standard dipping technique, and vector adults by Human Landing and pyrethrum spray catches methods. The vector population was composed of An. gambiae s.l. (> 99%) and An. funestus (hamlet Fourda) compared to farther inland Kéniéroba. The average infection rate of An. gambiae s.l. was 3.63% and 4.06% in Kéniéroba and Fourda respectively. The average entomological inoculation rate (EIR) during the study period was almost similar in Kéniéroba (0.70 infective bites/person/month) and Fourda (0.69 infective bites/person/month). The means EIRs over each of the rainy season 2006 and 2007 were always higher than the one of the dry season 2007 in both localities, with much smaller amplitude in Fourda than in Kéniéroba. However, the level of the transmission was 2.31 (0.37/0.16) times higher in Fourda than in Kéniéroba during the dry season.We conclude that in Sudan savanna zone of Mali, malaria transmission along the river is continuous throughout the year, but it is more intense in the immediate vicinity of the river during the dry season than during the rainy season in opposition to more distant localities to the river and vector control should not be focused only on the rainy in such setting.

  20. Emergency obstetrical complications in a rural African setting (Kayes, Mali): the link between travel time and in-hospital maternal mortality.

    Science.gov (United States)

    Pirkle, Catherine McLean; Fournier, Pierre; Tourigny, Caroline; Sangaré, Karim; Haddad, Slim

    2011-10-01

    The West African country of Mali implemented referral systems to increase spatial access to emergency obstetrical care and lower maternal mortality. We test the hypothesis that spatial access- proxied by travel time during the rainy and dry seasons- is associated with in-hospital maternal mortality. Effect modification by caesarean section is explored. All women treated for emergency obstetrical complications at the referral hospital in Kayes, Mali were considered eligible for study. First, we conducted descriptive analyses of all emergency obstetrical complications treated at the referral hospital between 2005 and 2007. We calculated case fatality rates by obstetric diagnosis and travel time. Key informant interviews provided travel times. Medical registers provided clinical and demographic data. Second, a matched case-control study assessed the independent effect of travel time on maternal mortality. Stratification was used to explore effect modification by caesarean section. Case fatality rates increased with increasing travel time to the hospital. After controlling for age, diagnosis, and date of arrival, a travel time of four or more hours was significantly associated with in-hospital maternal mortality (OR: 3.83; CI: 1.31-11.27). Travel times between 2 and 4 h were associated with increased odds of maternal mortality (OR 1.88), but the relationship was not significant. The effect of travel time on maternal mortality appears to be modified by caesarean section. Poor spatial access contributes to maternal mortality even in women who reach a health facility. Improving spatial access will help women arrive at the hospital in time to be treated effectively.

  1. Suppression of aggressive strains of 'Candidatus phytoplasma mali' by mild strains in Catharanthus roseus and Nicotiana occidentalis and indication of similar action in apple trees.

    Science.gov (United States)

    Schneider, Bernd; Sule, Sandor; Jelkmann, Wilhelm; Seemüller, Erich

    2014-05-01

    To study antagonistic interactions of 'Candidatus Phytoplasma mali' strains, graft inoculation of Catharanthus roseus and Nicotiana occidentalis was performed with mild strains 1/93Vin and 1/93Tab as suppressors and three aggressive strains as challengers. Inoculation of the suppressors was carried out in either the cross-protection modus prior to grafting of the challengers or by co-inoculating suppressors and challengers. Monitoring using multiplex real-time polymerase chain reaction assays revealed that, in long-term cross-protection trials with C. roseus, suppressor 1/93Vin was present in all root and randomly collected stem samples over the entire observation period. In contrast, the challengers were never detected in such stem samples and rarely in the roots. Following simultaneous inoculation, the suppressor successively colonized all stem and root regions whereas detection of challenger AT steadily decreased. However, this strain remained detectable in up to 13 and 27% of stem and root samples, respectively. The cross-protection trials with N. occidentalis yielded results similar to that of the cross-protection experiments with C. roseus. Comparison of the symptomatology of infected apple trees with the presence of putatively suppressive strains indicated that suppression of severe strains also occurs in apple. Phylogenetic analysis using a variable fragment of AAA+ ATPase gene AP460 of 'Ca. P. mali' revealed that suppressors 1/93Vin and 1/93Tab, together with several other mild strains maintained in apple, cluster distantly from obviously nonsuppressive strains that were predominantly highly virulent. PMID:24724815

  2. Anopheline (Diptera:Culicidae) breeding in a traditional tank-based village ecosystem in north central Sri Lanka

    DEFF Research Database (Denmark)

    Amerasinghe, F P; Konradsen, F; Fonseka, K T;

    1997-01-01

    A 13-mo survey of immature anopheline mosquitoes breeding in surface water habitats was done at Mahameegaswewa village within the Huruluwewa watershed in north central Sri Lanka as part of a multidisciplinary study on malaria epidemiology. The watershed is representative of the ancient small tank...

  3. Epidemiology of vampire bat-transmitted rabies virus in Goiás, central Brazil: re-evaluation based on G-L intergenic region

    OpenAIRE

    Ito Fumio H; Carvalho Adolorata AB; Itou Takuya; Hirano Shinji; Sakai Takeo

    2010-01-01

    Abstract Background Vampire bat related rabies harms both livestock industry and public health sector in central Brazil. The geographical distributions of vampire bat-transmitted rabies virus variants are delimited by mountain chains. These findings were elucidated by analyzing a high conserved nucleoprotein gene. This study aims to elucidate the detailed epidemiological characters of vampire bat-transmitted rabies virus by phylogenetic methods based on 619-nt sequence including unconserved G...

  4. Phylogenetic relationships between telmatobiinids (Anura, Ceratophryidae, Telmatobiinae of central Andes based on morphology of larval and adult stages

    Directory of Open Access Journals (Sweden)

    César Aguilar

    2011-07-01

    Full Text Available Batrachophrynus and Telmatobius are the two genus of Telmatobiinae from the central Andes. Both genera have species with adaptations for life at high altitude in the Andes, with aquatic or semi-aquatic habits in creeks, lagoons and lakes. The objective of this study is to evaluate the phylogenetic relationships between Batrachophrynus and 13 species of Telmatobius from the central Andes using larval and adult morphology including diagnostic characters for Batrachophrynus and Telmatobius, and putative sinapomorphies for Telmatobius. The phylogenetic analysis showed 20 parsimonious trees with 56 steps length. The results of this study hypothesize that the species assigned to Batrachophrynus form a monophyletic group nested within Telmatobius. In this study, most of the synapomorphies that support Telmatobius (including Batrachophrynus come from larval morphology and these sinapomorphies will probably support the whole genus.

  5. Governmental Accounting versus National Accounts: Implications of different accounting bases on EU member-States Central Government deficit/surplus

    OpenAIRE

    Maria Antónia Jorge de Jesus; Susana Margarida Jorge

    2012-01-01

    The main purpose of this paper is to assess the implications on the European Union (EU) member-States Central Government deficit/surplus of different accounting basis adopted in Governmental Accounting (GA – microeconomic perspective) and National Accounting (NA – macroeconomic perspective). It analyses the cash to accrual basis adjustments to be made to General Government Sector (GGS) data, when converting from Governmental Accounts to National Accounts. Additionally, it assesses the impact ...

  6. Evaluation of Collection, Staff and Space of the Central Library of Tarbiyat Modarress University based on LibQUAL Instrument

    OpenAIRE

    A'zam Najafgholinezhad; Mohammad Hassanzadeh

    2009-01-01

      The present investigation was carried out using LibQual software in order to evaluate the user view on the quality of services offered by the Central Library of Tarbiyat Modarress University. It was conducted at three levels of minimum, maximum and real. The sample was drawn from in-house and outside users, including graduate students and faculty members. Findings indicated that in most cases there is a difference between users’ expectations and the services offered by the library. Users’ d...

  7. Circulation of HIV-1 CRF02_AG among MSM Population in Central Italy: A Molecular Epidemiology-Based Study

    Directory of Open Access Journals (Sweden)

    Massimo Giuliani

    2013-01-01

    Full Text Available Introduction. The evolutionary and demographic history of the circular recombinant form CRF02_AG in a selected retrospective group of HIV-1 infected men who have sex with men (MSM resident in Central Italy was investigated. Methods. A total of 55 HIV-1 subtype CRF02_AG pol sequences were analyzed using Bayesian methods and a relaxed molecular clock to reconstruct their dated phylogeny and estimate population dynamics. Results. Dated phylogeny indicated that the HIV-1 CRF02_AG strains currently circulating in Central Italy originated in the early 90's. Bayesian phylogenetic analysis revealed the existence of a main HIV-1 CRF02_AG clade, introduced in the area of Rome before 2000 and subsequently differentiated in two different subclades with a different date of introduction (2000 versus 2005. All the sequences within clusters were interspersed, indicating that the MSM analyzed form a close and restricted network where the individuals, also moving within different clinical centers, attend the same places to meet and exchange sex. Conclusions. It was suggested that the HIV-1 CRF02_AG epidemic entered central Italy in the early 1990s, with a similar trend observed in western Europe.

  8. ecological geological maps: GIS-based evaluation of the Geo-Ecological Quality Index (GEQUI) in Sicily (Central Mediterranean)

    Science.gov (United States)

    Nigro, Fabrizio; Arisco, Giuseppe; Perricone, Marcella; Renda, Pietro; Favara, Rocco

    2010-05-01

    The condition of landscapes and the ecological communities within them is strongly related to levels of human activity. As a consequence, determining status and trends in the pattern of human-dominated landscapes can be useful for understanding the overall conditions of geo-ecological resources. Ecological geological maps are recent tools providing useful informations about a-biotic and biotic features worldwide. These maps represents a new generation of geological maps and depict the lithospheric components conditions on surface, where ecological dynamics (functions and properties) and human activities develop. Thus, these maps are too a fundamental political tool to plan the human activities management in relationship to the territorial/environmental patterns of a date region. Different types of ecological geological maps can be develop regarding the: conditions (situations), zoning, prognosis and recommendations. The ecological geological conditions maps reflects the complex of parameters or individual characteristics of lithosphere, which characterized the opportunity of the influence of lithosphere components on the biota (man, fauna, flora, and ecosystem). The ecological geological zoning maps are foundamental basis for prognosis estimation and nature defenses measures. Estimation from the position of comfort and safety of human life and function of ecosystem is given on these maps. The ecological geological prognosis maps reflect the spatial-temporary prognoses of ecological geological conditions changing during the natural dynamic of natural surrounding and the main-during the economic mastering of territory and natural technical systems. Finally, the ecological geological recommendation maps are based on the ecological geological and social-economical informations, aiming the regulation of territory by the regulation of economic activities and the defense of bio- and socio-sphere extents. Each of these maps may also be computed or in analytic or in

  9. Effects of aliskiren- and ramipril-based treatment on central aortic blood pressure in elderly with systolic hypertension: a substudy of AGELESS

    Directory of Open Access Journals (Sweden)

    Baschiera F

    2014-06-01

    Full Text Available Fabio Baschiera,1 William Chang,2 Patrick Brunel1 On behalf of the AGELESS Study Group 1Novartis Pharma AG, Basel, Switzerland; 2Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA Background: Systolic hypertension is the most common form of hypertension in elderly patients. There is increasing evidence that measurement of central aortic pressure (CAP better accounts for cardiovascular risk than brachial blood pressure (BP. The Aliskiren for GEriatric LowEring of SyStolic hypertension (AGELESS study in elderly patients with systolic hypertension showed that aliskiren-based therapy provided greater reductions in peripheral BP than ramipril-based therapy over 12 and 36 weeks of treatment. Here, we present CAP results in a substudy of elderly patients from the AGELESS study. Methods: This was a post hoc analysis of a 36-week, randomized, double-blind, parallel-group, active-controlled, optional-titration study in patients ≥65 years of age with systolic BP ≥140 mmHg. Changes in both central and peripheral BP and pulse pressure (PP and changes in systolic and PP amplification ratios from baseline to the week 36 end point with aliskiren-based versus ramipril-based therapy were analyzed. Results: Of the 901 patients randomized in the overall study, 154 patients (aliskiren, n=78; ramipril, n=76 had CAP data. Numerically comparable reductions were seen for central aortic systolic pressure (CASP in aliskiren-based therapy (baseline: 143.7±15.0; week 36: −20.3±16.2 compared with ramipril-based therapy (baseline: 147.9±11.9; week 36: −20.7±14.6. However, for the change in central aortic diastolic pressure, the least squares mean between-treatment difference (−3.6 mmHg [95% confidence interval, −6.76, −0.43; P=0.0263] was in favor of aliskiren, while the other changes were comparable between the two groups with a trend in favor of aliskiren for CASP as well (−2.6 mmHg [95% confidence interval, −7.38, 2.19; P=0

  10. Vesetation and climate changes during the last 8660 cal. a BP in central Mongolia, based on a high-resolution pollen record from Lake Ugii Nuur

    Institute of Scientific and Technical Information of China (English)

    WANG Wei; MA YuZhen; FENG ZhaoDong; MENG HongWei; SANG YanLi; ZHAI XinWei

    2009-01-01

    Based on modern pollen studies and reliable chronology of nine AMS 14C dates, a detailed history of vegetation and climate changes during the past 8660 cal. a BP was reconstructed by a high-resolution pollen record from Ugii Nuur in central Mongolia. Poaceae-steppe dominated the study area and the climate was mild and semi-humid before 7800 cal. a BP with a noticeable cool and humid interval at 8350-8250 cal. a BP. Xerophytic plant increased and the climate became warm and dry gradually since 7800 cal. a BP. From 6860 to 3170 cal. a BP, semi-desert steppe expanded, suggesting a prolonged warm and dry climate. Between 3170 and 2340 cal. a BP, regional forest steppe expanded whereas semi-desert steppe retreated, indicating the climate became cool and wet gradually and the humidity reached the maximum at the end of this stage. From 2340 to 1600 cal. a BP, a general cool and wet climate prevailed. And the climatic instability increased after 1600 cal. a BP. Review of regional pub-lished palaeoclimaUc records implies that the mid-Holocene dry climate might have prevailed in vast areas from central Mongolia to arid areas of northwest China. Pollen-based climate reconstruction for UG04 core was well correlated with the result of climate model on Central Asia by Bush. In addition, several abrupt climatic events (cool and wet) were found and some could be broadly compared with the cool events in Atlantic.

  11. Contemporary changes of water resources, water and land use in Central Asia based on observations and modeling.

    Science.gov (United States)

    Shiklomanov, A. I.; Prousevitch, A.; Sokolik, I. N.; Lammers, R. B.

    2015-12-01

    Water is a key agent in Central Asia ultimately determining human well-being, food security, and economic development. There are complex interplays among the natural and anthropogenic drivers effecting the regional hydrological processes and water availability. Analysis of the data combined from regional censuses and remote sensing shows a decline in areas of arable and irrigated lands and a significant decrease in availability of arable and irrigated lands per capita across all Central Asian countries since the middle of 1990thas the result of post-Soviet transformation processes. This change could lead to considerable deterioration in food security and human system sustainability. The change of political situation in the region has also resulted in the escalated problems of water demand between countries in international river basins. We applied the University of New Hampshire - Water Balance Model - Transport from Anthropogenic and Natural Systems (WBM-TrANS) to understand the consequences of changes in climate, water and land use on regional hydrological processes and water availability. The model accounts for sub-pixel land cover types, glacier and snow-pack accumulation/melt across sub-pixel elevation bands, anthropogenic water use (e.g. domestic and industrial consumption, and irrigation for most of existing crop types), hydro-infrastructure for inter-basin water transfer and reservoir/dam regulations. A suite of historical climate re-analysis and temporal extrapolation of MIRCA-2000 crop structure datasets has been used in WBM-TrANS for this project. A preliminary analysis of the model simulations over the last 30 years has shown significant spatial and temporal changes in hydrology and water availability for crops and human across the region due to climatic and anthropogenic causes. We found that regional water availability is mostly impacted by changes in extents and efficiency of crop filed irrigation, especially in highly arid areas of Central Asia

  12. A new PCR-based approach indicates the range of Clonorchis sinensis now extends to Central Thailand.

    Directory of Open Access Journals (Sweden)

    Rebecca J Traub

    Full Text Available Differentiation of the fish-borne trematodes belonging to the Opisthorchiidae, Heterophyidae and Lecithodendriidae is important from a clinical and epidemiological perspective, yet it is impossible to do using conventional coprological techniques, as the eggs are morphologically similar. Epidemiological investigation therefore currently relies on morphological examination of adult worms following expulsion chemotherapy. A PCR test capable of amplifying a segment of the internal transcribed spacer region of ribosomal DNA for the opisthorchiid and heterophyid flukes eggs taken directly from faeces was developed and evaluated in a rural community in central Thailand. The lowest quantity of DNA that could be amplified from individual adults of Opisthorchis viverrini, Clonorchis sinensis and Haplorchis taichui was estimated at 0.6 pg, 0.8 pg and 3 pg, respectively. The PCR was capable of detecting mixed infection with the aforementioned species of flukes under experimental conditions. A total of 11.6% of individuals in rural communities in Sanamchaikaet district, central Thailand, were positive for 'Opisthorchis-like' eggs in their faeces using conventional parasitological detection techniques. In comparison to microscopy, the PCR yielded a sensitivity and specificity of 71.0% and 76.7%, respectively. Analysis of the microscopy-positive PCR products revealed 64% and 23% of individuals to be infected with O. viverrini and C. sinensis, respectively. The remaining 13% (three individuals were identified as eggs of Didymozoidae, presumably being passed mechanically in the faeces following the ingestion of infected fishes. An immediate finding of this study is the identification and first report of a C. sinensis-endemic community in central Thailand. This extends the known range of this liver fluke in Southeast Asia. The PCR developed herein provides an important tool for the specific identification of liver and intestinal fluke species for future

  13. In silico Neuropeptidome of Female Macrobrachium rosenbergii Based on Transcriptome and Peptide Mining of Eyestalk, Central Nervous System and Ovary.

    Science.gov (United States)

    Suwansa-Ard, Saowaros; Thongbuakaew, Tipsuda; Wang, Tianfang; Zhao, Min; Elizur, Abigail; Hanna, Peter J; Sretarugsa, Prapee; Cummins, Scott F; Sobhon, Prasert

    2015-01-01

    Macrobrachium rosenbergii is the most economically important of the cultured freshwater crustacean species, yet there is currently a deficiency in genomic and transcriptomic information for research requirements. In this study, we present an in silico analysis of neuropeptide genes within the female M. rosenbergii eyestalk, central nervous system, and ovary. We could confidently predict 37 preproneuropeptide transcripts, including those that encode bursicons, crustacean cardioactive peptide, crustacean hyperglycemic hormones, eclosion hormone, pigment-dispersing hormones, diuretic hormones, neuropeptide F, neuroparsins, SIFamide, and sulfakinin. These transcripts are most prominent within the eyestalk and central nervous system. Transcript tissue distribution as determined by reverse transcription-polymerase chain reaction revealed the presence of selected neuropeptide genes of interest mainly in the nervous tissues while others were additionally present in the non-nervous tissues. Liquid chromatography-mass spectrometry analysis of eyestalk peptides confirmed the presence of the crustacean hyperglycemic hormone precursor. This data set provides a strong foundation for further studies into the functional roles of neuropeptides in M. rosenbergii, and will be especially helpful for developing methods to improve crustacean aquaculture.

  14. In silico Neuropeptidome of Female Macrobrachium rosenbergii Based on Transcriptome and Peptide Mining of Eyestalk, Central Nervous System and Ovary.

    Directory of Open Access Journals (Sweden)

    Saowaros Suwansa-Ard

    Full Text Available Macrobrachium rosenbergii is the most economically important of the cultured freshwater crustacean species, yet there is currently a deficiency in genomic and transcriptomic information for research requirements. In this study, we present an in silico analysis of neuropeptide genes within the female M. rosenbergii eyestalk, central nervous system, and ovary. We could confidently predict 37 preproneuropeptide transcripts, including those that encode bursicons, crustacean cardioactive peptide, crustacean hyperglycemic hormones, eclosion hormone, pigment-dispersing hormones, diuretic hormones, neuropeptide F, neuroparsins, SIFamide, and sulfakinin. These transcripts are most prominent within the eyestalk and central nervous system. Transcript tissue distribution as determined by reverse transcription-polymerase chain reaction revealed the presence of selected neuropeptide genes of interest mainly in the nervous tissues while others were additionally present in the non-nervous tissues. Liquid chromatography-mass spectrometry analysis of eyestalk peptides confirmed the presence of the crustacean hyperglycemic hormone precursor. This data set provides a strong foundation for further studies into the functional roles of neuropeptides in M. rosenbergii, and will be especially helpful for developing methods to improve crustacean aquaculture.

  15. A new permanent multi-parameter monitoring network in Central Asian high mountains – from measurements to data bases

    Directory of Open Access Journals (Sweden)

    T. Schöne

    2013-02-01

    Full Text Available Long-term monitoring of water resources and climate parameters at the scale of river basins requires networks of continuously operated in-situ stations. Since 2009, GFZ and CAIAG, in cooperation with the National Hydrometeorological Services (NHMS of Central Asia, are establishing such a regional monitoring network in Kazakhstan, Kyrgyzstan, Tajikistan, Uzbekistan, and lately Afghanistan to collect observations of meteorological and hydrological parameters and to deliver them to the end-users for operational tasks and scientific studies. The newly developed and installed remotely operated multi-parameter stations (ROMPS do not only monitor standard meteorological and hydrological parameters, but also deliver Global Navigation Satellite System (GNSS data for atmospheric sounding as well as tectonic studies. Additionally, three stations integrate seismic sensors for earthquake monitoring. The observational data from the ROMPS is transmitted nominally in near-real time, but at least once a day to a centralized geo-database infrastructure for long-term storage and data redistribution. Users can access the data manually using a web-interface or automatically using SOS requests; in addition, data is planed to be distributed to the NHMS through standard communication and data exchange channels.

  16. A new permanent multi-parameter monitoring network in Central Asian high mountains – from measurements to data bases

    Directory of Open Access Journals (Sweden)

    T. Schöne

    2012-06-01

    Full Text Available Long-term monitoring of water resources and climate parameters at the scale of river basins requires networks of continuously operated in-situ stations. Since 2009, GFZ and CAIAG, in cooperation with the National Hydrometeorological Services (NHMS, are establishing such a regional monitoring network in Central Asia (Kazakhstan, Kyrgyzstan, Tajikistan, Uzbekistan, and Afghanistan which is collecting observations of meteorological and hydrological parameters and delivering them to the end-users. The network design focuses mainly on the higher elevations where the recent decline of monitoring stations and networks established in Soviet times was strongest, and the resulting observational gap hinders research on climate and hydrological change as well as operational tasks in water management such as the seasonal runoff forecast. The newly developed and installed Remotely Operated Multi-Parameter Stations (ROMPS do not only monitor standard meteorological and hydrological parameters, but also deliver GPS data for atmospheric sounding as well as tectonic studies. The observational data from the ROMPS is transmitted at least once a day to a centralized geo-database infrastructure for long-term storage and data redistribution. Users can access the data manually using a web-interface or automatically using SOS requests; in addition, data is distributed to the NHMS through standard communication and data exchange channels.

  17. Social context of human immunodeficiency virus transmission in Africa: historical and cultural bases of east and central African sexual relations.

    Science.gov (United States)

    Larson, A

    1989-01-01

    The literature relating to the social context of sexual relations in East and Central Africa has several implications for the heterosexual transmission of human immunodeficiency virus (HIV). Colonially created cities in the region still discriminate economically and socially against women. Rapid urbanization is occurring, but migrants maintain strong ties with rural areas. Traditional attitudes towards marriage and sexuality affect urban behavior in the extent of marital stability, the frequency of polygyny, and the emotional bond between spouses. Ethnic groups in Kampala and Nairobi exemplify the cultural foundations of two forms of sexual relations found in the region, one characterized by prostitution and the other by small circles of interchanging lovers. The first results in a more rapid spread of HIV through the urban population and outwards into rural areas. Each pattern exerts unique constraints on behavioral change and requires different prevention campaigns. PMID:2682946

  18. Towards Food Security and Livelihoods of Low-income Women in central Uganda: Policy Implications based on action research

    DEFF Research Database (Denmark)

    Nambuanyi, Lekunze Ransom; Midtvåge, Runa; Hiranandani, Vanmala Sunder

    2015-01-01

    these constraints into opportunities for women by reflecting on how they can mitigate risks, adapt to climatic challenges and find alternative coping strategies, but suggests that policy options to enhance food security need to respond to the integrated framework of the issues. Additionally, this paper posits...... that the agricultural and livelihood choices women make are subject to the constraints they face and the policy alternatives available to them. As such it highlights certain policy considerations affecting food insecurity for low-income women in urban and peri-urban Kampala and makes certain key recommendations......Uganda is burdened with rising poverty, malnutrition and food insecurity. While most Ugandans depend on agriculture for their livelihoods, it is important to recognize that access to and control over resources by women and climate factors are central to the question of food security in Uganda...

  19. Mechanisms-based classifications of musculoskeletal pain: part 1 of 3: symptoms and signs of central sensitisation in patients with low back (± leg) pain.

    LENUS (Irish Health Repository)

    Smart, Keith M

    2012-08-01

    As a mechanisms-based classification of pain \\'central sensitisation pain\\' (CSP) refers to pain arising from a dominance of neurophysiological dysfunction within the central nervous system. Symptoms and signs associated with an assumed dominance of CSP in patients attending for physiotherapy have not been extensively studied. The purpose of this study was to identify symptoms and signs associated with a clinical classification of CSP in patients with low back (± leg) pain. Using a cross-sectional, between-subjects design; four hundred and sixty-four patients with low back (± leg) pain were assessed using a standardised assessment protocol. Patients\\' pain was assigned a mechanisms-based classification based on experienced clinical judgement. Clinicians then completed a clinical criteria checklist specifying the presence or absence of various clinical criteria. A binary logistic regression analysis with Bayesian model averaging identified a cluster of three symptoms and one sign predictive of CSP, including: \\'Disproportionate, non-mechanical, unpredictable pattern of pain provocation in response to multiple\\/non-specific aggravating\\/easing factors\\

  20. central t

    Directory of Open Access Journals (Sweden)

    Manuel R. Piña Monarrez

    2007-01-01

    Full Text Available Dado que la Regresión Ridge (RR, es una estimación sesgada que parte de la solución de la regresión de Mínimos Cuadrados (MC, es vital establecer las condiciones para las que la distribución central t de Student que se utiliza en la prueba de hipótesis en MC, sea también aplicable a la regresión RR. La prueba de este importante resultado se presenta en este artículo.

  1. Development of Kubłowo Palaeolake in Central Poland During Eemian Based on Subfossil Cladocera Analysis – Preliminary Results

    Directory of Open Access Journals (Sweden)

    Niska Monika

    2014-04-01

    Full Text Available The results of analysis of Cladocera occurrence in lacustrine sediments from the Kubłowo site have been presented. Lacustrine and peat deposits found there have been previously an analyzed for pollen content (depth of 11.1-3.8 m and represent a longest continuous Eemian-Vistulian succession in central Po land (Roman and Balwierz, 2010. Cladocera analysis was carried out on 25 samples from the depth of 9.20-10.5 m of an Eemian age section. The section consists of fine organic sand, silt with organic matter and gyttja. Identified were 19 species of subfossil Cladocera and five zones of fauna development were distinguished. In the early and mid-Eemian low frequency zooplankton in the palaeolake has been found. Best conditions for zooplankton development occurred in the late Eemian (R PAZ E6, E7. At the end of the Eemian a significant change of climate in a deterioration of environmental conditions and decreased presence of zoo plank ton has been noted. Cladocera results and the pollen data enable a reconstruction of the climatic and environmental changes in the Kubłowo palaeolake.

  2. The effect of precipitation and temperature anomalies for the Central-European forests based on Collection 6 MODIS data

    Science.gov (United States)

    Kern, Anikó; Marjanović, Hrvoje; Dobor, Laura; Barcza, Zoltán

    2016-04-01

    Forest phenology and productivity is intimately linked with the actual weather conditions, and in the long term with the local climate. Our current understanding on the environmental control on spring leaf-out and autumn senescence is incomplete. Causes of the interannual variability of tree growth and forest carbon balance are not well understood as well. Satellite remote sensing provides a feasible way to monitor and study the changes of forest functioning in general and to understand its relationship with the climate fluctuations. In the presented study the latest version (Collection 6) of the Enhanced Vegetation Index (EVI) and the Normalized Difference Vegetation Index (NDVI) products calculated from measurements of the MODIS sensor onboard the NASA Terra and Aqua satellites are used to characterize forest activity and its interannual variability in Central Europe (Hungary and Croatia). The applied EVI and NDVI dataset is part of the MOD13 product of NASA and covers the 2000-2015 time period. The newest, Collection 6 dataset is free from the sensor degradation effect (that was present in previous versions) which can contribute to the better characterization of the changes in forest phenology. Using the FORESEE climatological database the effects of drought is studied on the NDVI and EVI variations. Possible lagged effect of severe drought on NDVI variability during the consecutive years is studied at the selected sites. Drivers of forest phenology are studied in terms of linear relationships between temperature and onset/offset of the growing season.

  3. Modelling central metabolic fluxes by constraint-based optimization reveals metabolic reprogramming of developing Solanum lycopersicum (tomato) fruit.

    Science.gov (United States)

    Colombié, Sophie; Nazaret, Christine; Bénard, Camille; Biais, Benoît; Mengin, Virginie; Solé, Marion; Fouillen, Laëtitia; Dieuaide-Noubhani, Martine; Mazat, Jean-Pierre; Beauvoit, Bertrand; Gibon, Yves

    2015-01-01

    Modelling of metabolic networks is a powerful tool to analyse the behaviour of developing plant organs, including fruits. Guided by our current understanding of heterotrophic metabolism of plant cells, a medium-scale stoichiometric model, including the balance of co-factors and energy, was constructed in order to describe metabolic shifts that occur through the nine sequential stages of Solanum lycopersicum (tomato) fruit development. The measured concentrations of the main biomass components and the accumulated metabolites in the pericarp, determined at each stage, were fitted in order to calculate, by derivation, the corresponding external fluxes. They were used as constraints to solve the model by minimizing the internal fluxes. The distribution of the calculated fluxes of central metabolism were then analysed and compared with known metabolic behaviours. For instance, the partition of the main metabolic pathways (glycolysis, pentose phosphate pathway, etc.) was relevant throughout fruit development. We also predicted a valid import of carbon and nitrogen by the fruit, as well as a consistent CO2 release. Interestingly, the energetic balance indicates that excess ATP is dissipated just before the onset of ripening, supporting the concept of the climacteric crisis. Finally, the apparent contradiction between calculated fluxes with low values compared with measured enzyme capacities suggest a complex reprogramming of the metabolic machinery during fruit development. With a powerful set of experimental data and an accurate definition of the metabolic system, this work provides important insight into the metabolic and physiological requirements of the developing tomato fruits.

  4. Optimization of Jiawei Qing'e Oral Fast Disintegrating Tablets Based on Response Surface-Central Composite Design

    Institute of Scientific and Technical Information of China (English)

    ZHANG Wei-ling; WANG Ya-jing; GAO Xiu-mei; GAO Xu; PENG Shu-juan; ZHENG Yin; OKEKE Chukwunweike Ikechukwu

    2013-01-01

    Objective To apply the response surface-central composite design to developing and optimizing the oral fast disintegrating tablets (ODT) formulation for Jiawei Qing'e,a kind of prescription of Chinese herbal medicine.Methods The bitterness of Jiawei Qing'e was masked using Eudragit E-100 by solvent evaporation technique.Response surface approach was applied to investigating the interaction of formulation parameters in optimizing the formulation.The independent variables were Eudragit E-100/drug ratio (X1),amount of disintegrants (X2),and the amount of diluents (X3).The disintegration time (Y1),hardness (Y2),and weight variations of the tablets were characterized.Results The models predicted levels ofX1 =4.63%,X2 =5.25%,and X3 =34.33%,for the optimal formulation having a hardness of 3.0 kg with the disintegration time of 30 s within experimental region.The observed response of Y1 =26.5 s and Y2 =3.14 kg reasonably agreed with the predicted response.Conclusion Response surface methodology shows the good predictability and reliability in optimizing the formulation.The optimized ODT of Jiawei Qing'e has acceptable taste,rapid disintegrating ability,and good mechanical strength.

  5. Optimization of a spectrofluorimetric method based on a central composite design for the determination of potassium losartan in pharmaceutical products

    Directory of Open Access Journals (Sweden)

    Fatma Demirkaya-Miloglu

    2014-09-01

    Full Text Available Here, a spectrofluorimetric method for the determination of potassium losartan (PL in pharmaceutical products is described. The effects of critical parameters, pH, acid molarity, and temperature, on the fluorescence intensity of PL were analyzed, and these parameters were optimized using a central composite design (CCD. The highest fluorescent intensity at excitation (λex and emission (λem wavelengths of 248 nm and 410 nm, respectively, was achieved using 0.01 M sulfurous acid (pH 2 at 21.6 °C. Under optimum conditions, the method was linear from 0.025-0.5 µg/mL, with a reasonably high correlation coefficient (0.9993. Furthermore, the method was very sensitive (LOQ, 0.006, accurate (RE, ≤7.06, and precise (%RSD, ≤6.51. After development and validation of the method, samples containing PL were analyzed with this method, and the obtained data were statistically compared with those obtained with a previously published reference method using a two one-sided equivalence test (TOST. According to the data, the results from the proposed and reference assays were equivalent.

  6. Investigation on Fuzzy Logic Based Centralized Control in Four-Port SEPIC/ZETA Bidirectional Converter for Photovoltaic Applications

    Directory of Open Access Journals (Sweden)

    VENMATHI, M.

    2016-02-01

    Full Text Available In this paper, a new four-port DC-DC converter topology is proposed to interface renewable energy sources and the load along with the energy storage device. The proposed four-port SEPIC/ZETA bidirectional converter (FP-SEPIC/ZETA BDC converter comprises an isolated output port with two unidirectional and one bidirectional input ports. This converter topology is obtained by the fusion of SEPIC/ZETA BDC and full-bridge converter. This converter topology ensures the non-reversal of output voltage hence it is preferred mostly for battery charging applications. In this work, photovoltaic (PV source is considered and the power balance in the system is achieved by means of distributed maximum power point tracking (DMPPT in the PV ports. The centralized controller is implemented using fuzzy logic controller (FLC and the performance is compared with conventional proportional integral (PI controller. The results offer useful information to obtain the desired output under line and load regulations. Experimental results are also provided to validate the simulation results.

  7. Soil quality assessment using GIS-based chemometric approach and pollution indices: Nakhlak mining district, Central Iran.

    Science.gov (United States)

    Moore, Farid; Sheykhi, Vahideh; Salari, Mohammad; Bagheri, Adel

    2016-04-01

    This paper is a comprehensive assessment of the quality of soil in the Nakhlak mining district in Central Iran with special reference to potentially toxic metals. In this regard, an integrated approach involving geostatistical, correlation matrix, pollution indices, and chemical fractionation measurement is used to evaluate selected potentially toxic metals in soil samples. The fractionation of metals indicated a relatively high variability. Some metals (Mo, Ag, and Pb) showed important enrichment in the bioavailable fractions (i.e., exchangeable and carbonate), whereas the residual fraction mostly comprised Sb and Cr. The Cd, Zn, Co, Ni, Mo, Cu, and As were retained in Fe-Mn oxide and oxidizable fractions, suggesting that they may be released to the environment by changes in physicochemical conditions. The spatial variability patterns of 11 soil heavy metals (Ag, As, Cd, Co, Cr, Cu, Mo, Ni, Pb, Sb, and Zn) were identified and mapped. The results demonstrated that Ag, As, Cd, Mo, Cu, Pb, Sb, and Zn pollution are associated with mineralized veins and mining operations in this area. Further environmental monitoring and remedial actions are required for management of soil heavy metals in the study area. The present study not only enhanced our knowledge regarding soil pollution in the study area but also introduced a better technique to analyze pollution indices by multivariate geostatistical methods.

  8. Efficient GIS-based model-driven method for flood risk management and its application in central China

    Science.gov (United States)

    Liu, Y.; Zhou, J.; Song, L.; Zou, Q.; Guo, J.; Wang, Y.

    2014-02-01

    In recent years, an important development in flood management has been the focal shift from flood protection towards flood risk management. This change greatly promoted the progress of flood control research in a multidisciplinary way. Moreover, given the growing complexity and uncertainty in many decision situations of flood risk management, traditional methods, e.g., tight-coupling integration of one or more quantitative models, are not enough to provide decision support for managers. Within this context, this paper presents a beneficial methodological framework to enhance the effectiveness of decision support systems, through the dynamic adaptation of support regarding the needs of the decision-maker. In addition, we illustrate a loose-coupling technical prototype for integrating heterogeneous elements, such as multi-source data, multidisciplinary models, GIS tools and existing systems. The main innovation is the application of model-driven concepts, which put the system in a state of continuous iterative optimization. We define the new system as a model-driven decision support system (MDSS ). Two characteristics that differentiate the MDSS are as follows: (1) it is made accessible to non-technical specialists; and (2) it has a higher level of adaptability and compatibility. Furthermore, the MDSS was employed to manage the flood risk in the Jingjiang flood diversion area, located in central China near the Yangtze River. Compared with traditional solutions, we believe that this model-driven method is efficient, adaptable and flexible, and thus has bright prospects of application for comprehensive flood risk management.

  9. Evaluation of Collection, Staff and Space of the Central Library of Tarbiyat Modarress University based on LibQUAL Instrument

    Directory of Open Access Journals (Sweden)

    A'zam Najafgholinezhad

    2009-12-01

    Full Text Available   The present investigation was carried out using LibQual software in order to evaluate the user view on the quality of services offered by the Central Library of Tarbiyat Modarress University. It was conducted at three levels of minimum, maximum and real. The sample was drawn from in-house and outside users, including graduate students and faculty members. Findings indicated that in most cases there is a difference between users’ expectations and the services offered by the library. Users’ demands are somewhat satisfied at minimum level, but there is a significant gap with respect to desired level and users’ maximum expectations. Among different user groups, whether faculty or student, there is a significant difference with respect to the gap between the expectations and the services offered. There had been no significant difference of opinion among in-house and outside users regarding quality measures dealing with staff and the library space. There is however a significant difference regarding the quality of sources helf.   By using the factor analysis method, four factors were identified as contributing factors to the quality of library services. These were “availability and accessibility of sources”, “Availability of qualified and diligent staff”, “Suitability of space for individual or group study and learning” and “Ready Access to Information”.

  10. Uranium and thorium enrichment in rocks from the base of DSDP Hole 465A, Hess Rise, central North Pacific

    Science.gov (United States)

    Hein, J.R.; Koski, R.A.; Morgenson, L.A.

    1982-01-01

    Uranium and thorium are concentrated in Cretaceous limestone, chert, ash, basalt, and other rock types at Deep Sea Drilling Project Site 465 located on the southern Hess Rise in the central North Pacific. U concentrations, up to 194 ppm on a carbonate-free basis, are among the highest recorded for any deep-sea deposits. U was initially derived from seawater and concentrated by absorption on terrigenous (humic) organic matter in limestone in a shallow marine environment. U and Th were probably concentrated further by low-temperature hydrothermal fluids emanating from the basaltic basement. Mainly montmorillonite, an alteration product of basalt and ash, and organic matter in sedimentary rocks acted as hosts for U and Th. The unique combination of sediments rich in humic organic matter, abundant smectite in altered ash and basalt, and warm hydrothermal solutions provided the necessary conditions for migration and concentration of U and Th. To better understand the conditions limiting the migrating and concentration of U and Th, other rocks deposited during the ocean-wide Cretaceous anoxic events should be analyzed for these elements. ?? 1982.

  11. Conditions for the adoption of conservation agriculture in Central Morocco: an approach based on Bayesian network modelling

    Directory of Open Access Journals (Sweden)

    Laura Bonzanigo

    2016-03-01

    Full Text Available Research in Central Morocco, proves that conservation agriculture increases yields, reduces labour requirements, and erosion, and improves soil fertility. However, after nearly two decades of demonstration and advocacy, adoption is still limited. This paper investigates the critical constraints and potential opportunities for the adoption of conservation agriculture for different typologies of farms. We measured the possible pathways of adoption via a Bayesian decision network (BDN. BDNs allow the inclusion of stakeholders’ knowledge where data is scant, whilst at the same time they are supported by a robust mathematical background. We first developed a conceptual map of the elements affecting the decision about tillage, which we refined in a workshop with farmers and researchers from the Settat area. We then involved experts in the elicitation of conditional probabilities tables, to quantify the cascade of causal links that determine (or not the adoption. Via BDNs, we could categorise under which specific technical and socio-economic conditions no tillage agriculture is best suited to which farmers. We, by identifying the main constraints and running sensitivity analyses, were able to convey clear messages on how policy- makers may facilitate the conversion. As new evidence is collected, the BDN can be updated to obtain evidence more targeted and fine tuned to the adoption contexts.

  12. GRACE Data-based Estimation of Spatial Variations in Water Storage over the Central Asia during 2003-2013

    Science.gov (United States)

    Sun, Q.; Tashpolat, T.; Ding, J. L.; Zhang, F.; Mamat, S.

    2014-11-01

    We used the GRACE (Gravity Recovery And Climate Experiment) satellite gravity data obtained from January 2003 to January 2013, with supports of other data, including the TRMM (Tropical Rainfall Measuring Mission) and CMAP (Climate Prediction Center's Merged Analysis of Precipitation) precipitation data, the NDVI (Normalized Difference Vegetation Index) data, and the DEM (Digital Elevation Model) data, to analyze the annual variations in water storage over central Asia. Following conclusions can be drawn from this study. (1) The amplitudes of the annual variations in the water storage exhibit a general E-W increasing trend. (2) The water storage has an increasing trend in the following areas: the Balkhash Basin, the Ob River Basin, and the middle and lower reaches of the Yenisei River Basin. This is caused by the global warming, the melting of permafrost, and the vegetation coverage continued to increase, as well as the improved industrial technologies to reduce water usage, and the other natural and human factors. (3) The water storage has a decreasing trend in the following areas: the Syr Darya River Basin, the Amu Darya River Basin, and the conjunction area between the Euphrates-Tigris Basin and the southwestern shore of the Caspian Sea. (4) The water storage is primarily influenced by the precipitation, the evaporation, the vegetation coverage, and the topography. (5) The water storage maximum normally responds to the precipitation maximum with certain time lags.

  13. AFSC/NMML: Shore-based counts of the Eastern North Pacific gray whale stock from central California, 1967 - 2007

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Marine Fisheries Service (NMFS) has conducted shore-based counts of the Eastern North Pacific stock of gray whales (Eschrichtius robustus) 26 years...

  14. Use and Cost of Electronic Resources in Central Library of Ferdowsi University Based on E-metrics

    OpenAIRE

    Mohammad Reza Davarpanah; Nayereh Dadkhah

    2012-01-01

    The purpose of this study was to investigate the usage of electronic journals in Ferdowsi University, Iran based on e-metrics. The paper also aimed to emphasize the analysis of cost-benefit and the correlation between the journal impact factors and the usage data. In this study experiences of Ferdowsi University library on licensing and usage of electronic resources was evaluated by providing a cost-benefit analysis based on the cost and usage statistics of electronic resources. Vendor-provid...

  15. The Impact of Six Annual Rounds of Mass Drug Administration on Wuchereria bancrofti Infections in Humans and in Mosquitoes in Mali.

    Science.gov (United States)

    Coulibaly, Yaya I; Dembele, Benoit; Diallo, Abdallah Amadou; Konaté, Siaka; Dolo, Houseini; Coulibaly, Siaka Yamoussa; Doumbia, Salif Seriba; Soumaoro, Lamine; Coulibaly, Michel Emmanuel; Bockarie, Moses J; Molyneux, David; Nutman, Thomas B; Klion, Amy D; Toure, Yeya T; Traore, Sekou F

    2015-08-01

    Wuchereria bancrofti prevalence and transmission were assessed in six endemic villages in Sikasso, Mali prior to and yearly during mass drug administration (MDA) with albendazole and ivermectin from 2002 to 2007. Microfilaremia was determined by calibrated thick smear of night blood in adult volunteers and circulating filarial antigen was measured using immunochromatographic card test in children < 5 years of age. Mosquitoes were collected by human landing catch from July to December. None of the 686 subjects tested were microfilaremic 12 months after the sixth MDA round. More importantly, circulating antigen was not detected in any of the 120 children tested, as compared with 53% (103/194) before the institution of MDA. The number of infective bites/human/year decreased from 4.8 in 2002 to 0.04 in 2007, and only one mosquito containing a single infective larva was observed 12 months after the final MDA round. Whether this dramatic reduction in transmission will be sustained following cessation of MDA remains to be seen. PMID:26033027

  16. Stool microbiome reveals diverse bacterial ureases as confounders of oral urea breath testing for Helicobacter pylori and Mycobacterium tuberculosis in Bamako, Mali.

    Science.gov (United States)

    Maiga, Mamoudou; Cohen, Keira; Baya, Bocar; Srikrishna, Geetha; Siddiqui, Sophia; Sanogo, Moumine; Somboro, Anou M; Diarra, Bassirou; Diallo, Mariam H; Mazumdar, Varun; Yoder, Christian; Orsega, Susan; Belson, Michael; Kassambara, Hamadoun; Goita, Drissa; Murphy, Robert L; Dao, Sounkalo; Polis, Michael; Diallo, Souleymane; Timmins, Graham S; Dodd, Lori; Earl, Ashlee M; Bishai, William R

    2016-01-01

    Detection of bacterial urease activity has been utilized successfully to diagnose Helicobacter pylori (H. pylori). While Mycobacterium tuberculosis (M. tuberculosis) also possesses an active urease, it is unknown whether detection of mycobacterial urease activity by oral urease breath test (UBT) can be exploited as a rapid point of care biomarker for tuberculosis (TB) in humans. We enrolled 34 individuals newly diagnosed with pulmonary TB and 46 healthy subjects in Bamako, Mali and performed oral UBT, mycobacterial sputum culture and H. pylori testing. Oral UBT had a sensitivity and specificity (95% CI) of 70% (46-88%) and 11% (3-26%), respectively, to diagnose culture-confirmed M. tuberculosis disease among patients without H. pylori, and 100% sensitivity (69-100%) and 11% specificity (3-26%) to diagnose H. pylori among patients without pulmonary TB. Stool microbiome analysis of controls without TB or H. pylori but with positive oral UBT detected high levels of non-H. pylori urease producing organisms, which likely explains the low specificity of oral UBT in this setting and in other reports of oral UBT studies in Africa.

  17. Stool microbiome reveals diverse bacterial ureases as confounders of oral urea breath testing for Helicobacter pylori and Mycobacterium tuberculosis in Bamako, Mali.

    Science.gov (United States)

    Maiga, Mamoudou; Cohen, Keira; Baya, Bocar; Srikrishna, Geetha; Siddiqui, Sophia; Sanogo, Moumine; Somboro, Anou M; Diarra, Bassirou; Diallo, Mariam H; Mazumdar, Varun; Yoder, Christian; Orsega, Susan; Belson, Michael; Kassambara, Hamadoun; Goita, Drissa; Murphy, Robert L; Dao, Sounkalo; Polis, Michael; Diallo, Souleymane; Timmins, Graham S; Dodd, Lori; Earl, Ashlee M; Bishai, William R

    2016-01-01

    Detection of bacterial urease activity has been utilized successfully to diagnose Helicobacter pylori (H. pylori). While Mycobacterium tuberculosis (M. tuberculosis) also possesses an active urease, it is unknown whether detection of mycobacterial urease activity by oral urease breath test (UBT) can be exploited as a rapid point of care biomarker for tuberculosis (TB) in humans. We enrolled 34 individuals newly diagnosed with pulmonary TB and 46 healthy subjects in Bamako, Mali and performed oral UBT, mycobacterial sputum culture and H. pylori testing. Oral UBT had a sensitivity and specificity (95% CI) of 70% (46-88%) and 11% (3-26%), respectively, to diagnose culture-confirmed M. tuberculosis disease among patients without H. pylori, and 100% sensitivity (69-100%) and 11% specificity (3-26%) to diagnose H. pylori among patients without pulmonary TB. Stool microbiome analysis of controls without TB or H. pylori but with positive oral UBT detected high levels of non-H. pylori urease producing organisms, which likely explains the low specificity of oral UBT in this setting and in other reports of oral UBT studies in Africa. PMID:27532494

  18. Activity of Maly Aktru Glacier (Сentral Altai and changes tree line fluctuations in its basin for a historical period

    Directory of Open Access Journals (Sweden)

    A. N. Nazarov

    2016-01-01

    Full Text Available Major problems of dating of the glaciers activity from the wood residues found in moraines are discussed by the example of Maly Aktru Glacier. First of all, these are the underestimation of the glacier development features, the age of the sample itself and its content as well as losses of some outer rings. The study proves that disagreements between dendrochronological and radiocarbon ages of the samples are caused by manifestation of the Suess effect and contents of the wood cells. The reconstruction of June–July temperatures in the Aktru valley for two thousand years was used to reconstruct the altitudinal variability of the tree line thermal potential. Existence of a climatic optimum (I–IV A.D. had been revealed that brought to the higher position of the tree line in mid ages than its thermal potential could enable. On the basis of variability of growth indices for Siberian larch, it is shown that the medieval optimum stands out against a background of solely strong temperature depressions separating it from ancient and modern times, and the climate’s natural history is evidence that the current climate warming is an ordinary phenomenon.

  19. 马里费鲁水电站工程设计综述%Introduction to Project Design of Felou Hydropower Station in Mali

    Institute of Scientific and Technical Information of China (English)

    熊永成

    2014-01-01

    Felou hydropower station is located on the Senegal River within the territory of the Republic of Mali, Africa. The project is a run-off hydropower station, with a total installed capacity of 3 × 21MW. The paper makes an introduction to the general layout of the hydropower station and the design of each sub-item project. The international standards, whose design process catering to the World Bank's or the European Investment Bank's lending require-ments, are adopted for the project to get supporting loans from them.%∶马里费鲁水电站位于非洲马里共和国境内的塞内加尔河上,是一座径流引水式发电站,总装机容量为3×21MW。文中介绍水电站的总体布置和各分项设计情况。项目建设资金通过向世界银行和欧洲投资银行贷款,因此,采用国际标准设计,设计流程符合世界银行的要求。

  20. Quaternary paleoceanography of the central Arctic based on Integrated Ocean Drilling Program Arctic Coring Expedition 302 foraminiferal assemblages

    Science.gov (United States)

    Cronin, T. M.; Smith, S.A.; Eynaud, F.; O'Regan, M.; King, J.

    2008-01-01

    The Integrated Ocean Drilling Program (IODP) Arctic Coring Expedition (ACEX) Hole 4C from the Lomonosov Ridge in the central Arctic Ocean recovered a continuous 18 in record of Quaternary foraminifera yielding evidence for seasonally ice-free interglacials during the Matuyama, progressive development of large glacials during the mid-Pleistocene transition (MPT) ???1.2-0.9 Ma, and the onset of high-amplitude 100-ka orbital cycles ???500 ka. Foraminiferal preservation in sediments from the Arctic is influenced by primary (sea ice, organic input, and other environmental conditions) and secondary factors (syndepositional, long-term pore water dissolution). Taking these into account, the ACEX 4C record shows distinct maxima in agglutinated foraminiferal abundance corresponding to several interglacials and deglacials between marine isotope stages (MIS) 13-37, and although less precise dating is available for older sediments, these trends appear to continue through the Matuyama. The MPT is characterized by nearly barren intervals during major glacials (MIS 12, 16, and 22-24) and faunal turnover (MIS 12-24). Abundant calcareous planktonic (mainly Neogloboquadrina pachyderma sin.) and benthic foraminifers occur mainly in interglacial intervals during the Brunhes and very rarely in the Matuyama. A distinct faunal transition from calcareous to agglutinated foraminifers 200-300 ka in ACEX 4C is comparable to that found in Arctic sediments from the Lomonosov, Alpha, and Northwind ridges and the Morris Jesup Rise. Down-core disappearance of calcareous taxa is probably related to either reduced sea ice cover prior to the last few 100-ka cycles, pore water dissolution, or both. Copyright 2008 by the American Geophysical Union.

  1. Dust flux estimates for the Last Glacial Period in East Central Europe based on terrestrial records of loess deposits: a review

    Science.gov (United States)

    Újvári, Gábor; Kovács, János; Varga, György; Raucsik, Béla; Marković, Slobodan B.

    2010-11-01

    Loess-paleosol sequences are significant records of the mineral dust cycle of glacial-interglacial periods. As dust particles give rise to direct and indirect radiative forcing, obtaining a reliable picture of the global and regional patterns of mineral dust fluxes during glacial periods can lead to a better understanding of the contribution of mineral dust to past climate changes. Recent progress in absolute dating of loess deposits in the Carpathian Basin in East Central Europe made it possible to provide correct aeolian flux estimates for the Last Glacial period, marine isotope stage (MIS) 2. Mass accumulation rates (MARs) from chronological data of 33 loess sites exhibited a wide range of values, from 150 to 1422 g m -2 a -1, centered around median and mean values of 338 and 417 g m -2 a -1. MAR and MAR estimates have been also calculated using grain size measurements of many loess samples and loess MARs in order to facilitate comparison with models, and since particles larger than 10 μm have a negligible radiative effect. Here we show that some previous model simulations of the dust cycle at the Last Glacial Maximum (LGM) significantly underestimated the real aeolian flux (ranges of our estimates: MAR=34-324 and MAR=9.3-88.2 g m a) in East Central Europe. For this reason, some simulations of dust-induced direct radiative forcing of the LGM climate failed to yield reliable results for this mid-latitude region as they have been based on three-dimensional dust field models that are not capable of estimating the real aeolian fluxes in Central Europe. A recent global model of top of the atmosphere (TOA) radiative forcing by mineral aerosols at the LGM that has been based on more realistic parameterization of dust sources, transport, and deposition revealed zonally averaged surface cooling of -2 °C for the latitudes of our study area. This surface cooling and TOA radiative forcing (-2 to -3 W m -2) are greater than recognized in other models and draws our

  2. Survival of invasive bladder cancer patients, 1998–2009; a central and northern Denmark population-based cohort study

    Directory of Open Access Journals (Sweden)

    Lund L

    2011-07-01

    slightly in northern and central Denmark in the 1998–2009 period.Keywords: outcome research, MRR, mortality rate ratio

  3. Statistical discrimination of induced and tectonic earthquake sequences in Central and Eastern US based on waveform detected catalogs

    Science.gov (United States)

    Meng, X.; Daniels, C.; Smith, E.; Peng, Z.; Chen, X.; Wagner, L. S.; Fischer, K. M.; Hawman, R. B.

    2015-12-01

    Since 2001, the number of M>3 earthquakes increased significantly in Central and Eastern United States (CEUS), likely due to waste-water injection, also known as "induced earthquakes" [Ellsworth, 2013]. Because induced earthquakes are driven by short-term external forcing and hence may behave like earthquake swarms, which are not well characterized by branching point-process models, such as the Epidemic Type Aftershock Sequence (ETAS) model [Ogata, 1988]. In this study we focus on the 02/15/2014 M4.1 South Carolina and the 06/16/2014 M4.3 Oklahoma earthquakes, which likely represent intraplate tectonic and induced events, respectively. For the South Carolina event, only one M3.0 aftershock is identified by the ANSS catalog, which may be caused by a lack of low-magnitude events in this catalog. We apply a recently developed matched filter technique to detect earthquakes from 02/08/2014 to 02/22/2014 around the epicentral region. 15 seismic stations (both permanent and temporary USArray networks) within 100 km of the mainshock are used for detection. The mainshock and aftershock are used as templates for the initial detection. Newly detected events are employed as new templates, and the same detection procedure repeats until no new event can be added. Overall we have identified more than 10 events, including one foreshock occurred ~11 min before the M4.1 mainshock. However, the numbers of aftershocks are still much less than predicted with the modified Bath's law. For the Oklahoma event, we use 1270 events from the ANSS catalog and 182 events from a relocated catalog as templates to scan through continuous recordings 3 days before to 7 days after the mainshock. 12 seismic stations within the vicinity of the mainshock are included in the study. After obtaining more complete catalogs for both sequences, we plan to compare the statistical parameters (e.g., b, a, K, and p values) between the two sequences, as well as their spatial-temporal migration pattern, which may

  4. The Castle Mountain fault, south-central Alaska: New lidar-based observations on the sense of slip

    Science.gov (United States)

    Koehler, R. D.; Reger, D.; Frohman, R. A.

    2012-12-01

    The Castle Mountain fault extends along the southern Talkeetna Mountains rangefront and across the Susitna Lowland in south-central Alaska. The fault is an active structural element of the Aleutian forearc and has formed a 4-km-wide anticline associated with at least 0.5 km of north-side-up displacement. Right-lateral bedrock offsets along the eastern part of the fault are poorly constrained to ~14 km. In the Susitna Lowland, the fault is expressed at the surface by a distinct south-facing scarp. Previous paleoseismic studies have described the fault as both a strike-slip fault and a reverse fault, attributed the scarp to the occurrence of one to four paleoearthquakes, and estimated a Holocene right-lateral slip rate of ~3mm/yr. Motivated by inspection of new lidar data along the fault indicating that Holocene landforms are not laterally offset, we performed surficial-geologic mapping and field surveys with an emphasis on better characterizing the sense of slip. Field work was conducted along approximately 12 km of the scarp between Houston and Susitna River. Surficial-geologic mapping indicates that the fault displaces late Elmendorf (14-15 ka) glacial and Holocene deposits including glacial drift, sandy fan deltas, outwash plains, grounding-line moraines, basal-crevasse-fill complexes, stream terraces, oxbow lakes, and swamps. Where the scarp cuts these deposits it varies in height from ~ 0.5-4 m and is un-beveled. The surface trace also consists of left-stepping en echelon scarps and grabens. The grabens occur up to 400 m north of the scarp and indicate a wide zone of deformation. Numerous abandoned channels and stabilized sand dunes oriented orthogonal to the scarp are vertically offset and have negligible strike-slip displacement. The observations are consistent with reverse faulting above a north dipping fault associated with bending moment extensional grabens in the hanging wall. The en echelon pattern of scarps suggests a minor oblique component of slip. We

  5. Grief-Processing-Based Psychological Intervention for Children Orphaned by AIDS in Central China: A Pilot Study

    Science.gov (United States)

    Lin, Xiuyun; Fang, Xiaoyi; Chi, Peilian; Li, Xiaoming; Chen, Wenrui; Heath, Melissa Allen

    2014-01-01

    A group of 124 children orphaned by AIDS (COA), who resided in two orphanages funded by the Chinese government, participated in a study investigating the efficacy of a grief-processing-based psychological group intervention. This psychological intervention program was designed to specifically help COA process their grief and reduce their…

  6. How Central and Connected Am I in My Family? Family-Based Social Capital of Individuals with Intellectual Disability

    Science.gov (United States)

    Widmer, E. D.; Kempf-Constantin, N.; Robert-Tissot, C.; Lanzi, F.; Carminati, G. Galli

    2008-01-01

    Using social network methods, this article explores the ways in which individuals with intellectual disability (ID) perceive their family contexts and the social capital that they provide. Based on a subsample of 24 individuals with ID, a subsample of 24 individuals with ID and psychiatric disorders, and a control sample of 24 pre-graduate and…

  7. Contributions of separate reactions to the acid-base buffering of soils in brook floodplains (Central Forest State Reserve)

    Science.gov (United States)

    Sokolova, T. A.; Tolpeshta, I. I.; Rusakova, E. S.

    2016-04-01

    The acid-base buffering of gleyic gray-humus soils developed in brook floodplains and undisturbed southern-taiga landscapes has been characterized by the continuous potentiometric titration of soil water suspensions. During the interaction with an acid, the major amount of protons (>80%) is consumed for the displacement of exchangeable bases and the dissolution of Ca oxalates. In the O and AY horizons, Mn compounds make the major contribution (2-15%) to the acid buffering. The buffer reactions with the participation of Al compounds make up from 0.5 to 1-2% of the total buffering capacity, and the protonation of the surface OH groups of kaolinite consumes 2-3% of the total buffering capacity. The deprotonation of OH groups on the surface of Fe hydroxides (9-43%), the deprotonation of OH groups on the surface of illite crystals (3-19%), and the dissolution of unidentified aluminosilicates (9-14%) are the most significant buffer reactions whose contributions have been quantified during the interaction with a base. The contribution of the deprotonation of OH groups on the surface of kaolinite particles is lower (1-5%) because of the small specific surface area of this mineral, and that of the dissolution of Fe compounds is insignificant. In the AY horizon, the acid and base buffering of soil in the rhizosphere is higher than beyond the rhizosphere because of the higher contents of organic matter and nonsilicate Fe and Al compounds.

  8. Modelling the cometary structure of the planetary nebula HFG1 based on the evolution of its binary central star V664 Cas

    Science.gov (United States)

    Chiotellis, A.; Boumis, P.; Nanouris, N.; Meaburn, J.; Dimitriadis, G.

    2016-03-01

    HFG1 is the first well-observed planetary nebula (PN) which reveals a cometary-like structure. Its main morphological features consist of a bow-shaped shell, which surrounds the central star, accompanied by a long collimated tail. In this study, we perform two-dimensional hydrodynamic simulations modelling the formation of HFG1 from the interaction of the local ambient medium with the mass outflows of its asymptotic giant branch (AGB) progenitor star. We attribute the cometary appearance of HFG1 to the systemic motion of the PN with respect to the local ambient medium. Due to its vital importance, we re-estimate the distance of HFG1 by modelling the spectral energy distribution of its central star, V664 Cas, and we find a distance of 490 ± 50 pc. Our simulations show that none of our models with time invariant stellar wind and ambient medium properties are able to reproduce simultaneously the extended bow shock and the collimated tail observed in HFG1. Given this, we increase the complexity of our modelling considering that the stellar wind is time variable. The wind description is based on the predictions of the AGB and post-AGB evolution models. Testing a grid of models, we find that the properties of HFG1 are best reproduced by the mass outflows of a 3 M⊙ AGB star. Such a scenario is consistent with the current observed properties of V664 Cas primary star, an O-type subdwarf, and bridges the evolutionary history of HFG1 central star with the observables of the PN. We discuss the implications of our study in the understanding of the evolution of AGB/post-AGB stars towards the formation of O-type subdwarfs surrounded by PNe.

  9. DEM-based delineation for improving geostatistical interpolation of rainfall in mountainous region of Central Himalayas, India

    Science.gov (United States)

    Kumari, Madhuri; Singh, Chander Kumar; Bakimchandra, Oinam; Basistha, Ashoke

    2016-07-01

    In mountainous region with heterogeneous topography, the geostatistical modeling of the rainfall using global data set may not confirm to the intrinsic hypothesis of stationarity. This study was focused on improving the precision of the interpolated rainfall maps by spatial stratification in complex terrain. Predictions of the normal annual rainfall data were carried out by ordinary kriging, universal kriging, and co-kriging, using 80-point observations in the Indian Himalayas extending over an area of 53,484 km2. A two-step spatial clustering approach is proposed. In the first step, the study area was delineated into two regions namely lowland and upland based on the elevation derived from the digital elevation model. The delineation was based on the natural break classification method. In the next step, the rainfall data was clustered into two groups based on its spatial location in lowland or upland. The terrain ruggedness index (TRI) was incorporated as a co-variable in co-kriging interpolation algorithm. The precision of the kriged and co-kriged maps was assessed by two accuracy measures, root mean square error and Chatfield's percent better. It was observed that the stratification of rainfall data resulted in 5-20 % of increase in the performance efficiency of interpolation methods. Co-kriging outperformed the kriging models at annual and seasonal scale. The result illustrates that the stratification of the study area improves the stationarity characteristic of the point data, thus enhancing the precision of the interpolated rainfall maps derived using geostatistical methods.

  10. Central metal ion exchange in a coordination polymer based on lanthanide ions and di(2-ethylhexyl)phosphoric acid: exchange rate and tunable affinity.

    Science.gov (United States)

    Tasaki-Handa, Yuiko; Abe, Yukie; Ooi, Kenta; Tanaka, Mikiya; Wakisaka, Akihiro

    2014-01-01

    In this paper the exchange of lanthanide(III) ions (Ln(3+)) between a solution and a coordination polymer (CP) of di(2-ethylhexyl)phosphoric acid (Hdehp), [Ln(dehp)3], is studied. Kinetic and selectivity studies suggest that a polymeric network of [Ln(dehp)3] has different characteristics than the corresponding monomeric complex. The reaction rate is remarkably slow and requires over 600 h to reach in nearly equilibrium, and this can be explained by the polymeric crystalline structure and high valency of Ln(3+). The affinity of the exchange reaction reaches a maximum with the Ln(3+) possessing an ionic radius 7% smaller than that of the central Ln(3+), therefore, the affinity of the [Ln(dehp)3] is tunable based on the choice of the central metal ion. Such unique affinity, which differs from the monomeric complex, can be explained by two factors: the coordination preference and steric strain caused by the polymeric structure. The latter likely becomes predominant for Ln(3+) exchange when the ionic radius of the ion in solution is smaller than the original Ln(3+) by more than 7%. Structural studies suggest that the incoming Ln(3+) forms a new phase though an exchange reaction, and this could plausibly cause the structural strain.

  11. Risk Mapping and Situational Analysis of Cutaneous Leishmaniasis in an Endemic Area of Central Iran: A GIS-Based Survey

    Science.gov (United States)

    Abedi-Astaneh, Fatemeh; Hajjaran, Homa; Yaghoobi-Ershadi, Mohammad Reza; Hanafi-Bojd, Ahmad Ali; Mohebali, Mehdi; Shirzadi, Mohammad Reza; Rassi, Yavar; Akhavan, Amir Ahmad; Mahmoudi, Bagher

    2016-01-01

    Introduction Cutaneous leishmaniasis (CL) is among the top 10 infectious disease priorities in the world, and the leading cause of morbidity in Iran. The present study was conducted to assess the risk of CL, and to determine some epidemiological features of the disease in endemic areas of Qom Province in Central Iran during 2009 to 2013. Methods Data regarding human cases of the disease were obtained from the Qom Province Health Center, prepared and stored in a spatial database created in ArcGIS10.3. A total of 9 out of 212 Leishmania spp. positive slides taken in 2013 from patients residing in Qom city were examined using molecular methods and the species of Leishmania was identified by PCR-RFLP. Those 9 patients had no history of travel outside the city. Spatial analysis and clustering methods were applied to find major hot spots and susceptible areas for the establishment of novel foci of the disease. Transmission patterns were examined for spatial autocorrelation using the Moran's I statistical application, and for the clustering of high or low values using the Getis-Ord Gi* statistics. Results During the period of study, a total of 1767 CL cases were passively reported in the area, out of which were 65% males and 35% females. The highest and lowest numbers of cases were reported in 2010 and 2013, respectively. Importantly, 979 cases were reported from urban areas, while the remainder came from rural areas. Leishmania major was detected as the causative agent of CL in the city of Qom. Remarkably, most patients recorded in Qom city were associated with a history of travel to the endemic areas of CL within the province, or to other endemic areas of the disease in Iran. Spatial distribution of CL cases revealed northeastern and southwestern quarters of the city were the major hot spots of the disease (P<0.05). Hot spot and CL transmission risk analysis across the province indicated that more than 40 villages were located in high and very high risk areas of CL

  12. 一个基于中心度的社团结构发现新算法%New algorithm of detecting community structure based on degree centrality

    Institute of Scientific and Technical Information of China (English)

    戴爱明; 高学东; 王立敏

    2011-01-01

    Using GN algorithm to detect the community structure, there will be high time complexity. This paper proposed a new GN algorithm based on degree centrality ( DCGN). According to node degree centrality and the shortest path among them, the algorithm first confirmed the community structure central nodes, then deleted edges with the biggest betweenness among the community structure central nodes by step, to finish the community structure dividing. This algorithm got rid of high cost of parameter calculating when using GN algorithm, the algorithm ran in time O(cmn) when c was a constant, n was the number of network member, m was the number of network edge. Applied both this algorithm and GN algorithm to Zachary net and the net generated randomly by computer, and then compared them. Experiment results shows the proposed algorithm has advantage in feasibility and effectiveness.%针对GN算法在社团结构发现中时间复杂度高等问题,提出一种基于中心度的GN改进算法(DCGN).该算法根据节点中心度以及节点之间的最短路径首先确定社团结构中心节点集,然后逐步删除社团结构中心节点之间的最大边介数连边,完成社团结构划分.DCGN算法避免了GN算法边介数计算开销大的问题,算法的时间复杂度约为D(cmn),其中c为常数,n为网络成员数,m为网络连边数.将DCGN和GN算法同时应用到Za-chary网络及计算机随机生成网络中并进行了比较.实验结果表明,所提出的DCGN算法在运行效率和效果方面较之GN算法均具有一定的优势.

  13. Use and Cost of Electronic Resources in Central Library of Ferdowsi University Based on E-metrics

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Davarpanah

    2012-07-01

    Full Text Available The purpose of this study was to investigate the usage of electronic journals in Ferdowsi University, Iran based on e-metrics. The paper also aimed to emphasize the analysis of cost-benefit and the correlation between the journal impact factors and the usage data. In this study experiences of Ferdowsi University library on licensing and usage of electronic resources was evaluated by providing a cost-benefit analysis based on the cost and usage statistics of electronic resources. Vendor-provided data were also compared with local usage data. The usage data were collected by tracking web-based access locally, and by collecting vender-provided usage data. The data sources were one-year of vendor-supplied e-resource usage data such as Ebsco, Elsevier, Proquest, Emerald, Oxford and Springer and local usage data collected from the Ferdowsi university web server. The study found that actual usage values differ for vendor-provided data and local usage data. Elsevier has got the highest usage degree in searches, sessions and downloads. Statistics also showed that a small number of journals satisfy significant amount of use while the majority of journals were used less frequent and some were never used at all. The users preferred the PDF rather than HTML format. The data in subject profile suggested that the provided e-resources were best suited to certain subjects. There was no correlation between IF and electronic journal use. Monitoring the usage of e-resources gained increasing importance for acquisition policy and budget decisions. The article provided information about local metrics for the six surveyed vendors/publishers, e.g. usage trends, requests per package, cost per use as related to the scientific specialty of the university.

  14. Phenetic relationships among natural population accessions of Glycyrrhiza glabra L. (Fabaceae in central Zagros region of Iran, based on quantitative morphology, flavonoids and glycyrrhizin contents data

    Directory of Open Access Journals (Sweden)

    Majid Sharifi-Tehrani

    2013-01-01

    Full Text Available Phenetic relationships among thirty five accessions from natural populations of two varieties of Glycyrrhiza glabra in central Zagros region of Iran were studied. Twenty one quantitative morphological characters were measured for twenty seven accessions. PCO, clustering, K-means and MDS analyses were performed on morphological dataset. Polar flavonoid constituents of twenty four accessions were extracted, purified using TLC and characterized at the skeleton class level. Glycyrrhizin contents of rhizomes in twenty four accessions were quantified using image processing methods. Results of multivariate analysis of both morphological and flavonoid spot profile data showed that accessions could be partitioned into two main groups based on geographical locality of the populations. The most variable morphological trait based on CV values, was seed area and the least variable one was Legume width in the widest portion. Accessions of both varieties produced various flavonoids of class flavones and flavonols. Seven flavonoid constituents from the two varieties were separated based on different Rf values. The results revealed that there were moderate (not prominent levels of variation between the studied accessions. Separation of the varieties based on the single qualitative character in the available literature, was confirmed. Rhizomes of both varieties showed similar amounts of glycyrrhizin and almost similar types of flavonoids in their TLC profiles, suggesting that both were equivalent as herbal drugs in folk medicine.

  15. Assessment of standard compliance of Central European plastics-based wall cladding using multi-criteria decision making (MCDM

    Directory of Open Access Journals (Sweden)

    Daniel Friedrich

    2016-06-01

    Full Text Available Plastics are increasingly combined with renewable fibers to form materials such as wood-plastic composites (WPCs. These bio-based materials have gained the interest of the resource-intensive building industry and are currently used mainly for decking and cladding. Despite their environmental friendliness, WPC façades are still underrepresented in the market. This fact raises the question of whether WPC cladding is currently well positioned in the market and whether its attributes are advertised in a way that makes it stand out in a material selection process. A review of standards and codes relevant to façade design was carried out in this study, which allowed the identification of 21 product attributes as potential deciding factors in cladding product selection. Subsequently, the most promising attributes were used to assess commercially available plastics-based cladding products. By using multi-criteria decision making (MCDM it was found that WPC cladding is still far behind other cladding products with respect to standard compliance but has specific properties which support product optimization. MCDM can be used by WPC cladding manufacturers for strategic product development and by façade designers for material selection processes.

  16. Methodology for generation of heliostat field layout in central receiver systems based on yearly normalized energy surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, Marcelino; Romero, Manuel [DER-Plataforma Solar de Almeria, CIEMAT, Avda. Complutense 22, E-28040 Madrid (Spain)

    2006-07-15

    The heliostat field layout is an essential task for any solar tower plant optimization process. Radially staggered and other distributions are usually optimised by computer codes using different approaches. In most of those cases, due to the CPU time required, the heliostat field layout is optimised by several mathematical models and simplifications. With today's computers, it is possible to calculate the yearly energy available at any point in a site for a given tower height, the yearly normalized energy surface (YNES). Yearly efficiency maps can be generated based on the cosine factor, the spillage factor and the atmospheric attenuation coefficient of the site using real Direct Normal Irradiance (DNI) data, within a reasonable computing time. It is therefore easy to find the place where the yearly energy available is the highest for location of the first heliostat. It is also possible to calculate the effect of shadowing and blocking by this heliostat on the YNES, so YNES can be re-calculated and the best position for the next heliostat can be found. Although this iterative method is time-consuming, it is worthwhile if either the efficiency of the solar plant can be increased or the capital cost reduced. This YNES-based layout generation method enables better flexibility than pre-determined gridding strategies such as used in DELSOL. The paper includes a description of the optimization procedure. (author)

  17. An artificial vision-based control system for automatic heliostat positioning offset correction in a central receiver solar power plant

    Energy Technology Data Exchange (ETDEWEB)

    Berenguel, M. [Universidad de Almeria, Dept. de Lenguajes y Computacion, La Canada Almeria (Spain); Rubio, F.R.; Lara, P.J.; Arahal, M.R.; Camacho, E.F.; Lopez, M. [Universidad de Sevilla, Dept. de Ingenieria de Sistemas y Automatica, Sevilla (Spain); Valverde, A. [Plataforma Solar de Almeria (PSA-CIEMAT), Tabernas (Almeria) (Spain)

    2004-07-01

    This paper presents the development of a simplified and automatic heliostat positioning offset correction control system using artificial vision techniques and common CCD devices. The heliostats of a solar power plant reflect solar radiation onto a receiver (in this case, a volumetric receiver) placed at the top of a tower in order to provide a desired energy flux distribution correlated with the coolant flow (in this case air mass flow) through the receiver, usually in an open loop control configuration. There exist error sources that increase the complexity of the control system, some of which are systematic ones, mainly due to tolerances, wrong mirror facets alignment (optical errors), errors due to the approximations made when calculating the solar position, etc., that produce errors (offsets) in the heliostat orientation (aiming point). The approximation adopted in this paper is based on the use of a B/W CCD camera to correct these deviations in an automatic way imitating the same procedure followed by the operators. The obtained images are used to estimate the distance between the sunbeam centroid projected by the heliostats and a target placed on the tower, this distance thus is used for low accuracy offset correction purposes. Basic threshold-based image processing techniques are used for automatic correction. (Author)

  18. Genetic structure based on nuclear and chloroplast microsatellite loci of Solanum lycocarpum A. St. Hil. (Solanaceae) in Central Brazil.

    Science.gov (United States)

    Martins, K; Chaves, L J; Vencovsky, R; Kageyama, P Y

    2011-01-01

    Solanum lycocarpum (Solanaceae) is a woody species found in the Brazilian Cerrado. The flowers are pollinated by Xylocopa spp bees, and seeds are dispersed by mammals with distinct home range sizes. As a consequence, relative contributions of pollen and seeds to overall gene flow can vary according to different spatial scales. We studied the genetic structure of four natural populations of S. lycocarpum separated by 19 to 128 km, including individuals located along dirt roads that interlink three of the populations. A total of 294 individuals were genotyped with five nuclear and six chloroplast microsatellite markers. Significant spatial genetic structure was found in the total set of individuals; the Sp statistic was 0.0086. Population differentiation based on the six chloroplast microsatellite markers (θ(pC) = 0.042) was small and similar to that based on the five nuclear microsatellite markers (θ(p) = 0.054). For this set of populations, pollen and seed flow did not differ significantly from one another (pollen-to-seed flow ratio = 1.22). Capability for long distance seed dispersion and colonization of anthropogenic sites contributes to the ability of S. lycocarpum to maintain genetic diversity. Seed dispersion along dirt roads may be critical in preserving S. lycocarpum genetic diversity in fragmented landscapes. PMID:21523656

  19. Controls on mineralisation in the Sierra Foothills gold province, central California, USA: A GIS-based reconnaissance prospectivity analysis

    Science.gov (United States)

    Bierlein, F.P.; Northover, H.J.; Groves, D.I.; Goldfarb, R.J.; Marsh, E.E.

    2008-01-01

    The assessment of spatial relationships between the location, abundance and size of orogenic-gold deposits in the highly endowed Sierra Foothills gold province in California, via the combination of field studies and a GIS-based analysis, illustrates the power of such an approach to the characterisation of important parameters of mineral systems, and the prediction of districts likely to host economic mineralisation. Regional- to deposit-scale reconnaissance mapping suggests that deposition of gold-bearing quartz veins occurred in second- and third-order, east-over-west thrusts during regional east - west compression and right-lateral transpression. At the district-scale, significant zones of mineralisation correspond with such transpressional reactivation zones and dilational jogs that developed during the Late Jurassic - Early Cretaceous along the misaligned segments of first-order faults throughout the Sierra Nevada Foothills Metamorphic Belt. Field-based observations and interpretation of GIS data (including solid geology, structural elements, deposit locations, magnetics, gravity) also highlight the importance of structural permeability contrasts, rheological gradients, and variations in fault orientation for localising mineralisation. Although this approach confirms empirical findings and produces promising results at the province scale, enhanced geological, structural, geophysical and geochronological data density is required to generate regionally consistent, high-quality input layers that improve predictive targeting at the goldfield to deposit-scale.

  20. Tree-ring-based reconstruction of the April to September mean temperature since 1826 AD for north-central Shaanxi Province,China

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Long-time series of high-resolution temperature record from Chinese Loess Plateau is rare. An April-September mean temperature reconstruction (1826-2004) has been developed for the north-central Shaanxi Province, China, based on tree-ring width analysis. The reconstruction captures 39.3% (p<0.001) of the variance in the instrumental data over the calibration period from 1951 to 2002. The reconstruction shows a high temperature period of 1928-1933, which coincides with the timing of the extreme drought event in 1920s in the entire northern China. The two low temperature periods in reconstruction are 1883-1888 and 1938-1942. With the global warming, the April-September mean temperature in study area has also increased since the 1970s, but has not exceeded the temperature in 1928-1933. Besides the statistical analysis, the reconstruction is also verified by the local dryness/wetness index and other dendroclimatological results.