Influência de épocas de plantio e cultivares no rendimento total da cultura do alho (Allium sativum l. em Santa Maria, RS Planting date and cultivar influence on the total yield of garlic (Allium sativum L. in Santa Maria, RS

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Jorge Nadir Trevisan

1996-04-01

Full Text Available O experimento foi conduzido na Universidade Federal de Santa Maria, RS, no ano agrícola de 1984, afim de avaliar a influência de três épocas de plantio (27 de abril, 18 de maio e 14 de julho na produção total de bulbos de nove cultivares de alho (Allium sativum L.. Utilizou-se o delineamento de blocos ao acaso com parcelas subdivididas, com quatro repetições. Os maiores rendimentos totais de bulbos foram obtidos no plantio de 18 de maio. Gigante Lavínia foi a cultivar mais produtiva. As cultivares São Lourenço e Gigante Inconfidentes destacaram-se pelos rendimentos, os quais não diferiram significativamente entre si.The experiment was carried out at the Federal University of Santa Maria, in southernmost Brazil, during the growing season of 1984, to determine the influence of three different planting dates (April 27, May 18 and July 14 on the yield of nine garlic, Allium sativum Z., cultivars. The experimental design was a split plot complete block, with planting dates as main plots and cultivars as subplots. Blocks were replicated four times. The highest yields were obtained with planting date May 18. Gigante Lavínia ranked first among cultivars. The outstanding performances of São Lourenço and Gigante Inconfidentes were not significantly different.

The CBM first-level event selector

Energy Technology Data Exchange (ETDEWEB)

Cuveland, Jan de; Lindenstruth, Volker [Frankfurt Institute for Advanced Studies, Goethe University, Frankfurt (Germany)

2015-07-01

The CBM experiment currently under construction at GSI/FAIR is designed to study QCD predictions at high baryon densities. The CBM First-Level Event Selector (FLES) is the central event selection system of the experiment. Designed as a high-performance computer cluster, its task is an online analysis of the physics data including full event reconstruction at an incoming data rate exceeding 1 TByte/s. The CBM detector systems are free-running and self-triggered, delivering time-stamped data streams. As there is no inherent event separation, traditional approaches for global event building and event selection are not directly applicable. Instead of event building, the FLES combines the data from approximately 1000 input links to self-contained, overlapping processing intervals and distributes them to compute nodes. It employs a high-bandwidth InfiniBand network as well as dedicated custom FPGA input boards providing time-addressed access to buffered data. Subsequently, specialized event selection algorithms analyze these processing intervals in 4-D, identify events, and select those relevant for storage depending on the chosen CBM setup and selection scenario. This presentation outlines the design of the CBM First-level Event Selector and summarizes the results from first prototype systems.

Santa Rosa Geysers Recharge Project: GEO-98-001. Final Report

Energy Technology Data Exchange (ETDEWEB)

Brauner, Edwin Jr.; Carlson, Daniel C.

2002-10-01

The Geysers steamfields in northern Sonoma County have produced reliable ''green'' power for many years. An impediment to long-term continued production has been the ability to provide a reliable source of injection water to replace water extracted and lost in the form of steam. The steamfield operators have historcially used cooling towers to recycle a small portion of the steam and have collected water during the winter months using stream extraction. These two sources, however, could not by themselves sustain the steamfield in the long term. The Lake County Reclaimed Water Project (SEGEP) was inititated in 1997 and provides another source of steamfield replenishment water. The Santa Rosa Geysers Recharge Project provides another significant step in replenishing the steamfield. In addition, the Santa Rosa Geysers Recharge Project has been built with capacity to potentially meet virtually all injection water requirements, when combined with these other sources. Figure 2.1 graphically depicts the combination of injection sources.

Estudo fenológico em três fases sucessionais de uma floresta estacional decidual no município de Santa Tereza, RS, Brasil Phenology study in three successional stages of a seasonal deciduous forest in Santa Tereza, RS, Brazil

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Cáren Andreis

2005-02-01

Full Text Available O presente estudo foi realizado em 40 parcelas de área fixa pertencentes a três estágios sucessionais, denominados: Capoeirão, Floresta Secundária e Floresta Madura, em uma Floresta Estacional Decidual no município de Santa Tereza, RS. Foram realizadas observações fenológicas quinzenais em 53 espécies arbóreas, numa média de 8,4 indivíduos por espécie, durante o período de 16 de novembro de 2001 a 10 de novembro de 2002. As fenofases observadas foram floração, frutificação e mudança foliar. Os resultados indicaram que a atividade reprodutiva manteve uma porcentagem relativamente baixa nos três estágios sucessionais durante o período observado, com tendências em ser menor durante a estação de inverno. A quantidade total de folhas na árvore, não se distinguindo estágio sucessional, diminuiu de aproximadamente 85% no período de maior atividade vegetativa para até 35% no inverno, período de repouso, sendo a Floresta Madura a subsere, que manteve os maiores porcentuais de folhas durante o período estudado.The present study was accomplished in forty permanent plots belonging to three forest successional stages, denominated: Brush Forest, Secondary Forest and Mature Forest, in a seasonal deciduous forest in the municipal district of Santa Tereza, RS, Brazil. Phenologic observations were accomplished fortnightly for 53 arboreal species, in an average of 8,4 individuals per species, during the period of November 2001 to November 2002. The stages observed were flowering, fruiting and foliage change. The results indicate that the reproductive activity remained relatively low for three successional stages during the observed period, with a tendency to be even lower during winter. The total amount of leaves on the trees, regardless of the successional stage, decreased from approximately 85%, in the period of higher vegetative activity, to 35% in the winter, resting season. The Mature Forest maintained the largest percentage

CBM RICH geometry optimization

Energy Technology Data Exchange (ETDEWEB)

Mahmoud, Tariq; Hoehne, Claudia [II. Physikalisches Institut, Giessen Univ. (Germany); Collaboration: CBM-Collaboration

2016-07-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR complex will investigate the phase diagram of strongly interacting matter at high baryon density and moderate temperatures in A+A collisions from 2-11 AGeV (SIS100) beam energy. The main electron identification detector in the CBM experiment will be a RICH detector with a CO{sub 2} gaseous-radiator, focusing spherical glass mirrors, and MAPMT photo-detectors being placed on a PMT-plane. The RICH detector is located directly behind the CBM dipole magnet. As the final magnet geometry is now available, some changes in the RICH geometry become necessary. In order to guarantee a magnetic field of 1 mT at maximum in the PMT plane for effective operation of the MAPMTs, two measures have to be taken: The PMT plane is moved outwards of the stray field by tilting the mirrors by 10 degrees and shielding boxes have been designed. In this contribution the results of the geometry optimization procedure are presented.

Peter St. John | NREL

Science.gov (United States)

St. John Photo of Peter St. John Peter St. John Researcher III-Chemical Engineering Peter.StJohn @nrel.gov | 303-384-7969 Orcid ID http://orcid.org/0000-0002-7928-3722 Education Peter St. John received his engineering from the University of California at Santa Barbara in 2015. During his Ph.D., St. John applied

Endoplasmic reticulum stress mediating downregulated StAR and 3-beta-HSD and low plasma testosterone caused by hypoxia is attenuated by CPU86017-RS and nifedipine

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Liu Gui-Lai

2012-01-01

Full Text Available Abstract Background Hypoxia exposure initiates low serum testosterone levels that could be attributed to downregulated androgen biosynthesizing genes such as StAR (steroidogenic acute regulatory protein and 3-beta-HSD (3-beta-hydroxysteroid dehydrogenase in the testis. It was hypothesized that these abnormalities in the testis by hypoxia are associated with oxidative stress and an increase in chaperones of endoplasmic reticulum stress (ER stress and ER stress could be modulated by a reduction in calcium influx. Therefore, we verify that if an application of CPU86017-RS (simplified as RS, a derivative to berberine could alleviate the ER stress and depressed gene expressions of StAR and 3-beta-HSD, and low plasma testosterone in hypoxic rats, these were compared with those of nifedipine. Methods Adult male Sprague-Dawley rats were randomly divided into control, hypoxia for 28 days, and hypoxia treated (mg/kg, p.o. during the last 14 days with nifedipine (Nif, 10 and three doses of RS (20, 40, 80, and normal rats treated with RS isomer (80. Serum testosterone (T and luteinizing hormone (LH were measured. The testicular expressions of biomarkers including StAR, 3-beta-HSD, immunoglobulin heavy chain binding protein (Bip, double-strand RNA-activated protein kinase-like ER kinase (PERK and pro-apoptotic transcription factor C/EBP homologous protein (CHOP were measured. Results In hypoxic rats, serum testosterone levels decreased and mRNA and protein expressions of the testosterone biosynthesis related genes, StAR and 3-beta-HSD were downregulated. These changes were linked to an increase in oxidants and upregulated ER stress chaperones: Bip, PERK, CHOP and distorted histological structure of the seminiferous tubules in the testis. These abnormalities were attenuated significantly by CPU86017-RS and nifedipine. Conclusion Downregulated StAR and 3-beta-HSD significantly contribute to low testosterone in hypoxic rats and is associated with ER stress

Uma análise dos mitos que envolvem os alunos com altas habilidades: a realidade de uma escola de Santa Maria/RS An analysis of the myth that involves high ability students: the reality of a school from Santa Maria/RS

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Andréia Jaqueline Devalle Rech

2005-08-01

trajectory of high ability students. This happens due to the lack of knowledge, partly from some teachers, about ways of identifying and stimulating the talents of these students. This article presents results of a research proposed to investigate if the myth that involves students showing high abilities prevails in the conceptions of elementary school teachers from a public school of Santa Maria/RS. Ten teachers from afternoon shift, who teach from 1st to 4th grades, participated in this research. The defined instrument to the data collecting was the semi-structured interview that was applied individually in a reserved environment. A tape recorder was used to record the data upon previous authorization of the interviewed teachers. The content analysis was used as a way of "reading" the participants talking. As a result from the incidence of myth in the interviews with ten participants, it was noted that the teacher "A" can be observed in 60% of the mentioned myth while the others did not surpass 20%. This fact can be explained because that teacher did not participate in the research developed in the school in 2002 and 2003. The final considerations point out the importance of awareness from teachers that work in a regular classroom so that they can identify and direct students with giftedness characteristics to a specialized service.

The CBM RICH project

Energy Technology Data Exchange (ETDEWEB)

Adamczewski-Musch, J. [GSI Darmstadt (Germany); Becker, K.-H. [University Wuppertal (Germany); Belogurov, S. [ITEP Moscow (Russian Federation); Boldyreva, N. [PNPI Gatchina (Russian Federation); Chernogorov, A. [ITEP Moscow (Russian Federation); Deveaux, C. [University Gießen (Germany); Dobyrn, V. [PNPI Gatchina (Russian Federation); Dürr, M. [University Gießen (Germany); Eom, J. [Pusan National University (Korea, Republic of); Eschke, J. [GSI Darmstadt (Germany); Höhne, C. [University Gießen (Germany); Kampert, K.-H. [University Wuppertal (Germany); Kleipa, V. [GSI Darmstadt (Germany); Kochenda, L. [PNPI Gatchina (Russian Federation); Kolb, B. [GSI Darmstadt (Germany); Kopfer, J. [University Wuppertal (Germany); Kravtsov, P. [PNPI Gatchina (Russian Federation); Lebedev, S.; Lebedeva, E. [University Gießen (Germany); Leonova, E. [PNPI Gatchina (Russian Federation); and others

2014-12-01

The Compressed Baryonic Matter (CBM) experiment will study the properties of super dense nuclear matter by means of heavy ion collisions at the future FAIR facility. An integral detector component is a large Ring Imaging Cherenkov detector with CO{sub 2} gas radiator, which will mainly serve for electron identification and pion suppression necessary to access rare dileptonic probes like e{sup +}e{sup −} decays of light vector mesons or J/Ψ. We describe the design of this future RICH detector and focus on results obtained by building a CBM RICH detector prototype tested at CERN-PS.

Contaminação por compostos organoclorados em salsichas hot-dog comercializadas na cidade de Santa Maria (RS, Brasil Contamination for organochlorine compounds in hot-dog sausages, commercialized in the city of Santa Maria (RS, Brazil

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Stanislau Bogusz Junior

2004-10-01

Full Text Available Com o objetivo de monitorar os resíduos de compostos tóxicos em alimentos, verificou-se a freqüência e os níveis de praguicidas organoclorados (OC e bifenilas policloradas (PCBs em amostras de salsichas Hot-Dog, comercializadas na Cidade de Santa Maria, Estado do Rio Grande do Sul (RS e, compararam-se os valores com aqueles estabelecidos pela Legislação. Para as análises, procedeu-se a extração da gordura das amostras. A partir da purificação desta, obteve-se um extrato do qual se determinaram os resíduos organoclorados por cromatografia gasosa com detector de captura eletrônica (CG - µECD63Ni. Verificou-se que o lindano e o HCB foram os pesticidas que apresentaram as maiores concentrações médias (0,001798ppm e 0,001652ppm, respectivamente. O somatório dos níveis médios dos pesticidas organoclorados detectados foi de 0,015783ppm, sendo que deste total 0,011165ppm pertencia aos metabólitos do DDT. Quanto as bifenilas policloradas, as maiores concentrações médias corresponderam às PCBs 10 (0,001817ppm e 28 (0,000317ppm. O somatório das PCBs foi de 0,002172ppm. As concentrações de praguicidas organoclorados e PCBs encontradas nas amostras analisadas estavam abaixo dos limites máximos permitidos pela legislação.With the objective of monitoring toxic compounds residues in food, the frequency and levels of organochlorine pesticides and polychlorinated biphenyls were verified in sausage samples, hot dog type, commercialized in the city of Santa Maria (RS, Brazil. Values were compared with the ones established by Brazilian legislation. For the analyses the extraction of fat from the samples was done. From the purification of the fat, there was acquisition of an extract in which was determined the organochlorine contaminants residues by gas chromatography with electronic capture detector (CG - µECD63Ni. It was learned that the lindane and HCB were the pesticides that presented the biggest concentration averages (0

Perfil de adolescentes privados de liberdade em Santa Maria/RS Profile of adolescents deprived of freedom in Santa Maria/RS

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Jana Gonçalves Zappe

2010-08-01

Full Text Available Este trabalho apresenta as primeiras análises dos resultados da pesquisa intitulada "Adolescentes privados de liberdade: quem são, de onde vêm e para onde vão?", que teve como objetivo construir o perfil dos adolescentes que cumpriram medida socioeducativa de internação no Centro de Atendimento Socioeducativo Regional de Santa Maria durante o período de 1998 a 2007. As análises foram feitas através do programa Statistical Package for Social Sciences (Versão 14.0, e as características analisadas foram as seguintes: idade de ingresso, etnia, escolaridade e motivo do ingresso. Relacionamos esses resultados com a literatura sobre a situação social e psicológica em que se encontram os adolescentes autores de atos infracionais, constituindo-se como uma contribuição à construção de conhecimentos acerca dessa temática.This study presents the first analyzes of the data about the research entitled "Adolescents deprived of freedom: who are they, where do they come from and where do they go to?", which aimed to build up the profile of adolescents who have attended Socio-Educational Regional Care Center from Santa Maria, in the period of 1998 to 2007. The analyses were done by using the Statistical Package for Social Sciences (Version 14.0 Program. The variables analyzed were admission age, race/colour, educational records and reason for admission. We related these results with the literature on social and psychological situation of the adolescents who committed the infractional acts as a contribution to construct a body of knowledge on this subject.

EDUCAÇÃO E ETNICIDADE NA REGIÃO DE SANTA CRUZ DO SUL- RS. EDUCATION AND ETHNICITY IN THE REGION OF SANTA CRUZ DO SUL - RS

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Mozart Linhares da Silva

2012-11-01

Full Text Available O objetivo deste artigo é analisar as relações entre educação, etnicidade e mobilidade social em região de colonização alemã no Rio Grande do Sul, sobretudo em Santa Cruz do Sul, Brasil, cidade com forte discurso identitário germânico. Em que pese ser uma cidade caracterizada pelo germanismo, o que se constatou nas pesquisas até aqui realizadas, abrangendo os últimos seis anos, é que a região em questão possui significativa população de não-brancos, embora invisibilizada socialmente e excluída do processo de pertencimento identitário da comunidade regional. As pesquisas realizadas nas escolas municipais, estaduais e privadas na região de Santa Cruz do Sul permitem uma análise pontual das relações entre a educação e a imobilidade social, cujo resultado pode ser avaliado na dinâmica da visibilidade/invisibilidade identitária e processos de exclusão comunitário destes grupos, nomeadamente dos afrodescendentes.The objective of this article is to analyze the relations among education, ethnicity and social mobility in the region of German colonization in Rio Grande do Sul, and mainly in Santa Cruz do Sul, Brazil, a city with strong German identity speech. Taking into consideration that it is a city characterized by Germanism, what was observed in the researches accomplished until now, including the last six years, is that the region in question has a significant population of non-white people, though socially invisible and excluded from the identitary inclusion process of the region community. The researches that were carried out in the private and public – municipal and state – schools in the region of Santa Cruz do Sul permit sharp analysis of the relations between education and social immobility, which result can be evaluated in the identitary visibility/invisibility dynamic and processes of community exclusion of those groups, nominally of Afro-descendants.

ASPECTOS FITOSSOCIOLÓGICOS DE FRAGMENTO DE FLORESTA ESTACIONAL DECIDUAL, SANTA MARIA, RS

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Solon Jonas Longhi

2000-08-01

Full Text Available Foi realizado estudo da vegetação em fragmento de floresta estacional decidual em processo de sucessão, em área da Associação Tabor (29o43'S; 53o47'W, no município de Santa Maria (RS, Brasil. Utilizaram-se dezesseis unidades amostrais de 10 x 20 m distribuídas de forma sistemática para avaliação (medição e identificação dos indivíduos com Circunferência à Altura do Peito (CAP igual ou maior de 30 cm e subunidades circulares com raios de 1,78 m para identificação e contagem da regeneração (indivíduos menores de 30 cm. Observou-se a ocorrência de 64 espécies arbóreas e arbustivas de 54 gêneros e 31 famílias. As espécies com maior valor de importância foram Myrocarpus frondosus, Cupania vernalis, Ocotea puberula, Patagonula americana, Casearia sylvestris, Luehea divaricata, Enterolobium contortisiliquum e Helietta apiculata. Na regeneração, as espécies com maior densidade de indivíduos foram Trichilia elegans, Nectandra megapotamica, Actinostemon concolor, Piper gaudichaudianum, Cupania vernalis, Hybanthus bigibbosus, Aiouea saligna e Parapiptadenia rigida. Constatou-se o contínuo processo de sucessão por meio da substituição de espécies nos estratos da floresta e algumas bem-representadas desde a regeneração até o estrato superior.

[Description of communications of work accidents registered in the National Institute of Social Security of Santa Maria, RS, in the year 2000].

Science.gov (United States)

Kirchhof, Ana Lúcia Cardoso; Capellari, Claudia

2004-08-01

The communication of work accident is the document which warrants to the worker who suffered an accident the right to social benefit, and also serves as a source of epidemiological data. This study described the work accidents notified to the National Institute of Social Security of Santa Maria, RS, Brazil, in the year of 2000, attributing to them classifications that could be compared to Brazilian data and similar studies, among those the kind of accident, production sector and the worker's days off. It was possible to evidence the significant increase of notifications registered during the year of 2000 in relation to 1999, beyond the sub-register, specially in the scope of less serious accidents.

Antibodies against rabies virus in dogs with and without history of vaccination in Santa Maria - RS - Brazil

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Karina Gonzalez Fernandes

2017-10-01

Full Text Available ABSTRACT: The present study investigated the frequency and magnitude of neutralizing antibodies to rabies virus (RABV in dogs with and without historic of vaccination in Santa Maria/RS. Group A included serum samples from 440 dogs with recent historic of vaccination against rabies, obtained during the 2015 rabies vaccination campaign. Group B included 300 serum samples from dogs submitted to the Veterinary Hospital of the Universidade Federal de Santa Maria in 2015, whose historic of rabies vaccination was unknown. Serum samples were submitted to the rapid fluorescent focus inhibition test (RFFIT to detect neutralizing antibodies against RABV. In group A, 70.6% (310/440 of the samples had neutralizing antibody titers ≥0.5 international units per milliliter (IU mL-1, considered an indicative of protection against rabies by the World Health Organization. However, approximately 30% of the dogs did not contain antibodies in adequate levels. In group B, 42.3% (127/300 of the samples contained neutralizing antibody titers ≥0.5IU mL-1 and 57.7% (173/300 were negative or contained titers below of the value considered immunized. These results demonstrate that an important proportion of vaccinated dogs (~30% did not develop adequate antibody levels, mainly those receiving a single vaccine dose. Serologic testing of animals with unknown historic of vaccination revealed relatively low vaccine coverage in the general dog population. Thus, reformulation of immunization strategies - especially the recommendation of a boost vaccination 30 days after the primary dose - and extension of vaccination campaigns are necessary to reach adequate levels and coverage of immunity against RABV in the canine population.

Strangeness Prospects with the CBM Experiment

International Nuclear Information System (INIS)

Friese, Volker

2016-01-01

The CBM experiment will study strongly interacting matter at high net-baryon densities with nuclear collisions up to 45A GeV beam energy at the future FAIR facility. With interaction rates unprecedented in heavy-ion collisions, CBM will give access also to extremely rare probes and thus to the early stage of the collisions, in search for the first-order phase transition from confined to deconfined matter and the QCD critical point. The CBM physics programme will be started with beams delivered by the SIS-100 synchrotron, providing energies from 2 to 11 GeV/nucleon for heavy nuclei, up to 14 GeV/nucleon for light nuclei, and 30 GeV for protons. The highest net baryon densities will be explored with ion beams up to 45 GeV/nucleon energy delivered by SIS-300 in a later stage of the FAIR project.After several years of preparation, the CBM experiment now enters the realisation phase. In this article, we report on the current status of the system developments and the expected physics performance for strange and charmed observables, as well as on the roadmap towards the first data taking. (paper)

DETERMINAÇÃO DOS VALORES MÉDIOS DAS ENZIMAS AST, DHL, gGT E FAS NO SORO DE EQUINOS SADIOS EM SANTA MARIA, RS

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Sônia Terezinha dos Anjos Lopes

1993-12-01

Full Text Available Foram usados 50 eqüinos sadios provenientes do Batalhão de Polícia Montada da Brigada Militar em Santa Maria, RS, sendo 43 machos e 7 fêmeas com idade variadas a partir de 3 anos. Foram colhidos 10ml de sangue da jugular para determinação dos valores da atividade sérica das enzimas aspartato-aminotransferase (AST, desidrogenase lática (DHL, gama-glutamiltransferase (gGT e fosfatase alcalina sérica (FAS. Os resultados encontrados para AST foi de 101 - 190U/I com média de 130UI; DHL foi de 100 - 421 U/l com média de 182U/I; gGT foi de 2 - 27U/I com média de 6.5U/I e FAS foi de 103 - 335U/I com média de 190U/I. A partir de outubro/1992 estes valores passaram a ser referência no laboratório de Patologia Clínica do Hospital de Clinicas Veterinárias da Universidade Federal de Santa Maria.

Construção civil: análise do comportamento da mão de obra e da produtividade na cidade de santa maria (RS

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Camila Candida Compagnoni Dos Reis

2017-01-01

Full Text Available A construção brasileira retomou nos anos recentes o seu importante papel na receita do desenvolvimento. Após décadas de baixo investimento em infraestrutura e em habitação, o país reencontrou sua rota de progresso. Nesse novo cenário evidenciam-se grandes desafios, o principal deles, na trajetória de crescimento continuado, é o da produtividade. É neste contexto que se insere o presente trabalho, objetivando analisar a produtividade da mão de obra da Construção Civil no setor de habitação na cidade de Santa Maria (RS, bem como analisar qual é o perfil de funcionários mais utilizados nas construções. Para atingir os objetivos, este trabalho tem como referência os dados do Sindicato da Construção de Santa Maria – 8RS entre os anos de 2009 e 2014. Houve, no período analisado, avanços na produtividade induzidos pela própria dinâmica de crescimento e por investimentos em treinamento das construtoras da cidade. Verificou-se uma correlação forte entre área construída e mão de obra utilizada pelas construtoras. Constatou-se também um aumento dos estoques em 2012, seguido de uma alta da área construída nos meses de 2013, acarretando nesse ano o pico do número de empregados na Construção Civil na série em estudo.

The potential for coalbed methane (CBM) development in Alberta

International Nuclear Information System (INIS)

2001-09-01

This report presents fiscal and regulatory recommendations of the coalbed methane (CBM) Advisory Committee which consists of representatives from Alberta's oil and gas industry who participated in a study to determine the potential for coalbed methane development in the province. CBM is a natural gas produced as a by-product of the coal formation process. This study examined the CBM reserve base in Alberta along with the necessary steps and strategies required to develop it. There is increased interest in natural gas from Alberta's coal resources because of the forecast for reasonable natural gas prices coupled with an increase in energy demand. The remaining established natural gas reserves are estimated at 43 trillion cubic feet and unconventional supplies of natural gas will be needed by 2008 to meet this increasing demand. The recoverable reserves of CBM are estimated to be between 0 and 135 trillion cubic feet. This report discussed the following mitigation strategies suggested by industry that may applicable to CBM development in Alberta: (1) potential technical mitigation strategies, (2) potential land access and tenure strategies, (3) potential water disposal and diversion mitigation strategies, (4) potential non-technical mitigation strategies, and (5) potential economic mitigation strategies. The study concluded that since no two CBM basins are the same, it is necessary to have good baseline resource inventory data. It was also noted that evolving management, drilling and completion techniques will continue to enhance the economic understanding of Alberta's extensive coal beds. It was suggested that lessons from CBM development in the United States can be useful for development in Alberta since there are currently no publicly recognized commercial production of CBM in Alberta. 24 refs., 6 tabs., 25 figs

Development of the geometry database for the CBM experiment

Science.gov (United States)

Akishina, E. P.; Alexandrov, E. I.; Alexandrov, I. N.; Filozova, I. A.; Friese, V.; Ivanov, V. V.

2018-01-01

The paper describes the current state of the Geometry Database (Geometry DB) for the CBM experiment. The main purpose of this database is to provide convenient tools for: (1) managing the geometry modules; (2) assembling various versions of the CBM setup as a combination of geometry modules and additional files. The CBM users of the Geometry DB may use both GUI (Graphical User Interface) and API (Application Programming Interface) tools for working with it.

PROCESSO DE COLETA SELETIVA DE RESÍDUOS SÓLIDOS: UM ESTUDO DE CASO DE SUSTENTABILIDADE NA CIDADE DE SANTA MARIA/RS

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Sérgio Luiz Oliveira de Almeida Júnior

2015-07-01

Full Text Available O presente artigo tem por objetivo verificar se o processo seletivo utilizado pela Prefeitura Municipal de Santa Maria/RS proporciona sustentabilidade às associações de catadores participantes. A pesquisa se caracteriza como descritiva de cunho bibliográfica, com uso de técnicas de coleta de dados: questionário e observação sistemática. Os resultados comprovam que a população não está separando o lixo adequadamente visto o grande volume de resíduos não recicláveis encontrados pelas associações. Este fator pode ser revertido com práticas de divulgação e educação, enfatizando que a coleta seletiva é uma alternativa ecologicamente correta, pois evita a contaminação dos solos e água, contribuindo para a sustentabilidade planetária. As associações confirmam que o processo contribui para a sustentabilidade local e para a instituição pesquisada. Conclui-se que o processo seletivo de coleta de lixo que a Prefeitura Municipal está adotando proporciona sustentabilidade às associações e aos santa-marienses, pois contribui com o meio ambiente e com a melhoria na qualidade de vida da população.

Avaliação da qualidade do leite cru comercializado informalmente em feiras livres no município de Santa Maria-RS / Quality assessment of raw milk informally commercialized in street markets in the city of Santa Maria-RS

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Márcia Liliane Rippel Silveira

2014-05-01

Full Text Available O objetivo deste trabalho foi avaliar a qualidade do leite cru comercializado informalmente em feiras livres no município de Santa Maria, RS. Amostras de leite cru foram adquiridas diretamente dos feirantes em feiras livres e a avaliação da qualidade do leite foi realizada por meio de análises físico-químicas e microbiológicas. Dez amostras de leite cru informal foram analisadas, mas apenas duas não apresentaram alterações em relação à acidez titulável. Dessas duas amostras, os parâmetros de densidade e gordura apresentaram resultado satisfatório, ao contrário do índice crioscópico, teor de proteína e extrato seco desengordurado, que apresentaram valores em desacordo com os padrões estabelecidos. Em relação às análises microbiológicas, 30% das amostras apresentaram contagem de micro-organismos mesófilos superior a 6,0x105 UFC/mL e a presença de coliformes termotolerantes foi confirmada em todas as amostras de leite cru, porém nenhuma apresentava contaminação por Salmonella sp. Considerando que este produto é comercializado de forma clandestina, os resultados obtidos evidenciam a precariedade higiênica do leite comercializado nas feiras livres. O consumo do leite cru sem qualquer tipo de controle higiênico-sanitário expõe a saúde do consumidor a riscos. ------------------------------------------------------------------------ The objective of this paper was to evaluate the quality of raw milk informally commercialized in street markets in the city of Santa Maria, RS. Samples of raw milk were purchased directly from merchants in street markets and the milk quality evaluation was performed through physical-chemical and microbiological analysis. Ten samples of informal raw milk were analyzed, but only two showed no variation from the titrable acidity. In these two samples, the parameters of density and fat showed satisfactory results, in opposition to the cryoscopic index, protein and fat dry extract that

Superconducting dipole magnet for the CBM experiment at FAIR

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Kurilkin P.

2017-01-01

Full Text Available The scientific goal of the CBM (Compressed Baryonic Matter experiment at FAIR (Darmstadt is to explore the phase diagram of strongly interacting matter at highest baryon densities. The physics program of the CBM experiment is complimentary to the programs to be realized at MPD and BMN facilities at NICA and will start with beam derived by the SIS100 synchrotron. The 5.15 MJ superconducting dipole magnet will be used in the silicon tracking system of the CBM detector. The magnet will provide a magnetic field integral of 1 Tm which is required to obtain a momentum resolution of 1% for the track reconstruction. The results of the development of dipole magnet of the CBM experiment are presented.

Dewatering CBM's bad image : improved technologies and improved economics are helping CBM industry emerge from the shadows

International Nuclear Information System (INIS)

Collison, M.

2009-01-01

Coalbed methane (CBM) is an emerging source of energy with a resource base in the foothills of British Columbia and Alberta, the grasslands of east-central Alberta, and the east coast of Canada. This paper described the new royalty framework that should stimulate recovery of methane from low-volume shallow coal seams in the Horseshoe Canyon formation. Under the new structure, royalties are sensitive to low-productivity wells as well as prices. There is also a revised program for deep drilling that will help CBM operators using multi-leg horizontal drilling techniques. Calgary-based Trident Resources Corporation launched the one and only deep wet coal project in Alberta in 2005 near Fort Assiniboine. The company also announced that it had reached 650,000 metres of horizontal and multilateral horizontal drilling in the first commercial Mannville CBM gas field in Canada. In an effort to address issues regarding the CBM sector's bad environmental reputation, the Alberta Department of Energy created a CBM Multi-stakeholder Advisory Committee (MAC) to protect water resources, enhance information and knowledge, minimize surface impacts, and improve communication consultation. Progress has been made in enhanced water well testing and analysis; initiation of a groundwater inventory project; completion of updates to the base of groundwater protection database; and improved access to information with stakeholders and the public. Production of natural gas from coal can also be enhanced by injecting carbon dioxide (CO 2 ). Depending on the local geology, CO 2 injection can increase methane production from 30 to 300 per cent for the equivalent land surface disturbance. However, the technology is not yet commercial because of the prohibitive cost of high-purity CO 2 . Pilot studies in China will allow participants to evaluate the commercial prospects of the technology for global applications. 2 figs

The CBM RICH project

Energy Technology Data Exchange (ETDEWEB)

Adamczewski-Musch, J. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, D-64291 Darmstadt (Germany); Akishin, P. [Laboratory of Information Technologies, Joint Institute for Nuclear research (JINR-LIT), Dubna (Russian Federation); Becker, K.-H. [Department of Physics, University of Wuppertal, D-42097 Wuppertal (Germany); Belogurov, S. [SSC RF ITEP, 117218 Moscow (Russian Federation); Bendarouach, J. [Institute of Physics II and Institute of Applied Physics, Justus Liebig University Giessen, D-35392 Giessen (Germany); Boldyreva, N. [National Research Centre “Kurchatov Institute” B.P. Konstantinov Petersburg Nuclear Physics Institute, 188300 Gatchina (Russian Federation); Chernogorov, A. [SSC RF ITEP, 117218 Moscow (Russian Federation); Deveaux, C. [Institute of Physics II and Institute of Applied Physics, Justus Liebig University Giessen, D-35392 Giessen (Germany); Dobyrn, V. [National Research Centre “Kurchatov Institute” B.P. Konstantinov Petersburg Nuclear Physics Institute, 188300 Gatchina (Russian Federation); Dürr, M. [Institute of Physics II and Institute of Applied Physics, Justus Liebig University Giessen, D-35392 Giessen (Germany); Eschke, J. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, D-64291 Darmstadt (Germany); Förtsch, J. [Department of Physics, University of Wuppertal, D-42097 Wuppertal (Germany); Heep, J.; Höhne, C. [Institute of Physics II and Institute of Applied Physics, Justus Liebig University Giessen, D-35392 Giessen (Germany); Kampert, K.-H. [Department of Physics, University of Wuppertal, D-42097 Wuppertal (Germany); and others

2017-02-11

The CBM RICH detector is an integral component of the future CBM experiment at FAIR, providing efficient electron identification and pion suppression necessary for the measurement of rare dileptonic probes in heavy ion collisions. The RICH design is based on CO{sub 2} gas as radiator, a segmented spherical glass focussing mirror with Al+MgF{sub 2} reflective coating, and Multianode Photomultipliers for efficient Cherenkov photon detection. Hamamatsu H12700 MAPMTs have recently been selected as photon sensors, following an extensive sensor evaluation, including irradiation tests to ensure sufficient radiation hardness of the MAPMTs. A brief overview of the detector design and concept is given, results on the radiation hardness of the photon sensors are shown, and the development of a FPGA-TDC based readout chain is discussed.

Danos físicos em estufas plásticas causados pelo vento em Santa Maria, RS Plastic greenhouses damaged by wind in Santa Maria, RS. Case report

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Nereu Augusto Streck

1998-03-01

Full Text Available Foram observados danos físicos causados por rajadas de vento ocorridos na madrugada do dia 19/05/97 no plástico das estufas localizadas no Campus da Universidade Federal de Santa Maria. Os valores de intensidade e direção das rajadas máximas do vento foram registradas em um anemográfo universal tipo IH 1023 a 10m de altura, instalado a aproximadamente 100m ao sul das estufas. Os danos ocorreram quando a velocidade das rajadas máximas ultrapassou 20m s-1 (72km h-1Plastic greenhouses located at the Federal University of Santa Maria, Rio Grande do Sul State, Brazil were damaged by wind on May 19th, 1997. Wind speed and direction at 10m height were measured at the Climatological Station located approximatly 100m from the greenhouses. The damage in the greenhouses occured when the maximum gusts reached up speed higher than 20m s-1 (72km h-1.

Decision-Making Accuracy of CBM Progress-Monitoring Data

Science.gov (United States)

Hintze, John M.; Wells, Craig S.; Marcotte, Amanda M.; Solomon, Benjamin G.

2018-01-01

This study examined the diagnostic accuracy associated with decision making as is typically conducted with curriculum-based measurement (CBM) approaches to progress monitoring. Using previously published estimates of the standard errors of estimate associated with CBM, 20,000 progress-monitoring data sets were simulated to model student reading…

Overview of DAQ developments for the CBM experiment

Energy Technology Data Exchange (ETDEWEB)

Emschermann, David [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH (Germany); Collaboration: CBM-Collaboration

2015-07-01

The Compressed Baryonic Matter experiment (CBM) at the future Facility for Antiproton and Ion Research (FAIR) is a a fixed-target setup operating at very high interaction rates up to 10 MHz. The high rate capability can be achieved with fast and radiation hard detectors equipped with free-streaming readout electronics. A high-speed data acquisition (DAQ) system will forward data volumes of up to 1 TB/s from the CBM cave to the first level event selector (FLES), located 400 m apart. This presentation showcases recent developments of DAQ components for CBM. We highlight the anticipated DAQ setup for beam tests scheduled for the end of 2015.

The Predictive Validity of CBM Writing Indices for Eighth-Grade Students

Science.gov (United States)

Amato, Janelle M.; Watkins, Marley W.

2011-01-01

Curriculum-based measurement (CBM) is an alternative to traditional assessment techniques. Technical work has begun to identify CBM writing indices that are psychometrically sound for monitoring older students' writing proficiency. This study examined the predictive validity of CBM writing indices in a sample of 447 eighth-grade students.…

Present state of condition based maintenance (CBM) and its future problem

International Nuclear Information System (INIS)

Hashimoto, Satoshi; Nogami, Takeki; Sugiyama, Naoki

2008-01-01

New inspection system of the nuclear power plant will be introduced from 2008. In this feature, eleven experts from electric utilities, venders and academia described their views or activities about Condition Based Maintenance (CBM) with a new inspection system attracting attention. These are titled as 'Electric utilities view on CBM and its technology', Deployment results of developed CBM technologies', 'Valve diagnostic analysis support system with wireless technology applied', 'Portable vibration checker', 'Tribology diagnosis with no overhaul', 'Infrared thermograph diagnosis', 'Pipewall thinning inspection and management' and, in addition, the US trend and also the development trend of the CBM advancement technology in the vender and university. CBM technology will be introduced step-by-step and contribute to establish reliability based maintenance. (T. Tanaka)

Santa Teresa y sus cartas, historia de los sentimientos

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Egido, Teófanes

2015-12-01

Full Text Available Historical reflection on a peculiar dimension of St. Teresa of Jesus: the expression of her feelings in her writings, particularly in her abundant letters. The article focuses on the sense of humor, the joyfulness, and the importance of laughter in St. Teresa language, and also on the feeling of endearment with her family, with her order, with fray Juan de la Cruz. Ample space is dedicated to the tenderness towards girls in her convents. St. Teresa of Jesus appears as transgressor of 16th century social behaviours.Reflexión histórica sobre una dimensión peculiar de santa Teresa de Jesús: la expresión de sus sentimientos en sus escritos, de forma más especial en sus cartas abundantes. El artículo se centra en el sentido del humor, de la alegría, en la importancia de la risa en el lenguaje de santa Teresa y en el sentimiento de ternura con su familia, con su orden, con fray Juan de la Cruz. Se dedica un espacio amplio a la ternura hacia las niñas en sus conventos. Aparece santa Teresa de Jesús como trasgresora de los comportamientos sociales del siglo XVI.

Positive imagery cognitive bias modification (CBM) and internet-based cognitive behavioural therapy (iCBT) versus control CBM and iCBT for depression: study protocol for a parallel-group randomised controlled trial.

Science.gov (United States)

Williams, Alishia D; Blackwell, Simon E; Holmes, Emily A; Andrews, Gavin

2013-10-29

The current randomised controlled trial will evaluate the efficacy of an internet-delivered positive imagery cognitive bias modification (CBM) intervention for depression when compared with an active control condition and help establish the additive benefit of positive imagery CBM when delivered in combination with internet cognitive behavioural therapy for depression. Patients meeting diagnostic criteria for a current major depressive episode will be recruited through the research arm of a not-for-profit clinical and research unit in Australia. The minimum sample size for each group (α set at 0.05, power at 0.80) was identified as 29, but at least 10% more will be recruited to hedge against expected attrition. We will measure the impact of CBM on primary measures of depressive symptoms (Beck Depression Inventory-second edition (BDI-II), Patient Health Questionnaire (PHQ9)) and interpretive bias (ambiguous scenarios test-depression), and on a secondary measure of psychological distress (Kessler-10 (K10)) following the 1-week CBM intervention. Secondary outcome measures of psychological distress (K10), as well as disability (WHO disability assessment schedule-II), repetitive negative thinking (repetitive thinking questionnaire), and anxiety (state trait anxiety inventory-trait version) will be evaluated following completion of the 11-week combined intervention, in addition to the BDI-II and PHQ9. Intent-to-treat marginal and mixed effect models using restricted maximum likelihood estimation will be used to evaluate the primary hypotheses. Clinically significant change will be defined as high-end state functioning (a BDI-II score reduction greater than the reliable change index score. Maintenance of gains will be assessed at 3-month follow-up. The current trial protocol has been approved by the Human Research Ethics Committee of St Vincent's Hospital and the University of New South Wales, Sydney. Australian New Zealand Clinical Trials Registry: ACTRN12613000139774

O USO DO GEOPROCESSAMENTO NA ANÁLISE ESPACIAL DOS CONDOMÍNIOS E LOTEAMENTOS FECHADOS EM SANTA CRUZ DO SUL- RS

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Jonis Bozzetti

2014-06-01

Full Text Available A cidade de Santa Cruz do Sul, localizada na região do Vale do Rio Pardo – RS, constitui-se no principal polo agroindustrial de tabaco do mundo e também em importante centro regional de comércio e serviços. Nos últimos trinta anos, a cidade passou por intensas e desiguais transformações em seus processos de evolução urbana e de urbanização. Um desses processos tem sido a intensa produção de novos produtos imobiliários: loteamentos e condomínios fechados. Com o auxílio de técnicas de geoprocessamento, foi possível melhor analisar esses empreendimentos, identificando a segregação espacial, os impactos ambientais e a injustiça fiscal que esses produtos tem representado na dinâmica de organização e de uso do espaço urbano na cidade.

UM OLHAR SOBRE O PROCESSO DE TRANSFORMAÇÃO DA PAISAGEM NA BACIA DO RIO SANTA ROSA (NW DO RS), DE 1915 ATÉ OS DIAS ATUAIS

OpenAIRE

Adriana Fátima Canova Motter

2011-01-01

Esta pesquisa teve por objetivo analisar a transformação da paisagem no que se refere ao manejo com a floresta, ao uso do solo e dos recursos hídricos na bacia hidrográfica do rio Santa Rosa (NW do RS), a partir de 1915; quando do início da colonização e ocupação do espaço por imigrantes europeus e seus descendentes. Partiu-se da hipótese de que a ideia de progresso, para os imigrantes, esteve associada à abertura de áreas agrícolas nas regiões de florestas nativas. A partir disso...

Detector performance tests for the CBM TRD

Energy Technology Data Exchange (ETDEWEB)

Kohn, Martin [Institut fuer Kernphysik, WWU Muenster (Germany)

2016-07-01

The Compressed Baryonic Matter (CBM) experiment is a fixed target heavy-ion experiment at the future FAIR accelerator facility. The CBM Transition Radiation Detector (TRD) is one of the key detectors to provide electron identification and charged particle tracking. With the construction phase of the detector nearing, we will present results of the detector obtained with a close to final prototype. These results were achieved in measurements at CERN PS in 2014 and SPS in 2015.

Comunidade de Syrphidae (Diptera: diversidade e preferências florais no Cinturão Verde (Santa Cruz do Sul, RS, Brasil Syrphidae (Diptera community: diversity and floral preferences in the Green Belt (Santa Cruz do Sul, RS, Brazil

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Mírian Nunes Morales

2008-01-01

Full Text Available Objetivou-se investigar a comunidade de Syrphidae, do Cinturão Verde de Santa Cruz do Sul, RS, Brasil, permitindo a obtenção de informações acerca da composição e estrutura desta comunidade, suas preferências florais e interações entre as espécies na utilização de recursos alimentares. Realizaram-se coletas com rede entomológica, entre setembro/2001 a janeiro/2005. Foram capturados 1.283 espécimes de Syrphidae, representados por 88 espécies, distribuídos em 21 gêneros. Eristalinae apresentou o maior número de espécies coletadas, seguida por Syrphinae e Microdontinae. O gênero Palpada Macquart e a espécie P. urotaenia (Curran foram os mais abundantes. As coletas alcançaram cerca de 80% do que se estima para a área de estudo. Coletaram-se 1.187 sirfídeos (74 espécies visitantes de 51 espécies de plantas, de 23 famílias, onde Apiaceae e Asteraceae apresentaram o maior número de visitantes. O grau de especialização alimentar variou de acordo com os tipos de flores visitadas. A facilidade do acesso aos recursos florais e a coloração clara das flores são os principais responsáveis pela atração dos sirfídeos em Apiaceae, Asteraceae, Lauraceae, Malvaceae, Meliaceae, Oleaceae, Poaceae e Solanaceae. A diversidade da comunidade de Syrphidae é regulada por interações locais entre as espécies, principalmente entre as condições ambientais e disponibilidade de recursos alimentares.The aim of this study was to investigate the Syrphidae community in the area of the Green Belt of Santa Cruz do Sul, RS, Brazil, as well as to obtain information on the structure and composition of this community, its floral preferences and the interactions between the species in the food resource utilization. The specimens were collected with entomological net, from September/2001 to January/2005. A total of 1.283 syrphid specimens were collected, totaling 88 species distributed in 21 genera. Eristalinae presented the highest number of

Electron identification capabilities of the CBM experiment at FAIR

Energy Technology Data Exchange (ETDEWEB)

Hoehne, Claudia; Kisel, Ivan [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Lebedev, Semen [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Laboratory of Information Technologies, Joint Institute for Nuclear Research, Dubna (Russian Federation); Ososkov, Gennady [Laboratory of Information Technologies, Joint Institute for Nuclear Research, Dubna (Russian Federation)

2010-07-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR facility at Darmstadt will measure dileptons emitted from the hot and dense phase in heavy-ion collisions. In case of an electron measurement, a high purity of identified electrons is required in order to suppress the background. Electron identification in CBM will be performed by a RICH and TRD detectors. In this contribution, methods which have been developed for the electron identification in CBM are presented. A fast and efficient RICH ring recognition algorithm based on the Hough Transform has been implemented. An ellipse fitting algorithm has been elaborated because most of the CBM RICH rings have elliptic shapes. An Artificial Neural Network can be used in order to suppress fake rings. The electron identification in RICH is substantially improved by the use of TRD detectors for which several different algorithms for electron identification are implemented. Results of electron identification and pion suppression are presented.

Attribute Synthetic Evaluation Model for the CBM Recoverability and Its Application

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Xiao-gang Xia

2015-01-01

Full Text Available The coal-bed methane (CBM recoverability is the basic premise of CBM development practice; in order to effectively evaluate the CBM recoverability, the attribute synthetic evaluation model is established based on the theory and method of attribute mathematics. Firstly, five indexes are chosen to evaluate the recoverability through analyzing the influence factors of CBM, including seam thickness, gas saturation, permeability, reservoir pressure gradient, and hydrogeological conditions. Secondly, the attribute measurement functions of each index are constructed based on the attribute mathematics theory, and the calculation methods of the single index attribute measurement and the synthetic attribute measurement also are provided. Meanwhile, the weight of each index is given with the method of similar number and similar weight; the evaluation results also are determined by the confidence criterion reliability code. At last, according to the application results of the model in some coal target area of Fuxin and Hancheng mine, the evaluation results are basically consistent with the actual situation, which proves that the evaluation model can be used in the CBM recoverability prediction, and an effective method of the CBM recoverability evaluation is also provided.

Reactor kinetics revisited: a coefficient based model (CBM)

International Nuclear Information System (INIS)

Ratemi, W.M.

2011-01-01

In this paper, a nuclear reactor kinetics model based on Guelph expansion coefficients calculation ( Coefficients Based Model, CBM), for n groups of delayed neutrons is developed. The accompanying characteristic equation is a polynomial form of the Inhour equation with the same coefficients of the CBM- kinetics model. Those coefficients depend on Universal abc- values which are dependent on the type of the fuel fueling a nuclear reactor. Furthermore, such coefficients are linearly dependent on the inserted reactivity. In this paper, the Universal abc- values have been presented symbolically, for the first time, as well as with their numerical values for U-235 fueled reactors for one, two, three, and six groups of delayed neutrons. Simulation studies for constant and variable reactivity insertions are made for the CBM kinetics model, and a comparison of results, with numerical solutions of classical kinetics models for one, two, three, and six groups of delayed neutrons are presented. The results show good agreements, especially for single step insertion of reactivity, with the advantage of the CBM- solution of not encountering the stiffness problem accompanying the numerical solutions of the classical kinetics model. (author)

Solar radiation availability for tomato cropping during winter in Santa Maria, RS, Brazil

International Nuclear Information System (INIS)

Estefanel, V.; Buriol, G.A.; Andriolo, J.L.; Lima, C.P.; Luzzi, N.

1998-01-01

The probability of occurrence of days with solar radiation bellow the critical value for the development of tomato inside greenhouse in Santa Maria, Rio Grande do Sul State, were calculated during May, June, July and August. It was considered the flue density of solar radiation of 200 cal cm -2 dia -1 as the lowest value to tomato growth and 180 cal cm -2 dia -1 as the low value reference of solar radiation for crop growth. Daily values of solar radiation were estimated by sunshine duration during the time period from 1912 to 1996. Results showed that the availability of solar radiation in Santa Maria was lower than the required by tomato crop inside plastic greenhouse during Winter, mainly in June and July. (author) [pt

Production performance laws of vertical wells by volume fracturing in CBM reservoirs

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Liehui Zhang

2017-05-01

Full Text Available Volume fracturing technology has been widely applied in the development of coalbed methane (CBM reservoirs. As for the stimulated reservoir volume (SRV created by volume fracturing, the seepage laws of fluids are described more accurately and rationally in the rectangular composite model than in the traditional radial composite model. However, the rectangular composite model considering SRV cannot be solved using the analytical or semi-analytical function method, and its solution from the linear flow model has larger errors. In view of this, SRV areas of CBM reservoirs were described by means of dual-medium model in this paper. The complex CBM migration mechanisms were investigated comprehensively, including adsorption, desorption, diffusion and seepage. A well testing model for rectangular composite fracturing wells in CBM reservoirs based on unsteady-state diffusion was built and solved using the boundary element method combined with Laplace transformation, Stehfest numerical inversion and computer programming technology. Thus, production performance laws of CBM reservoirs were clarified. The flow regimes of typical well testing curves were divided and the effects on change laws of production performance from the boundary size of gas reservoirs, permeability of volume fractured areas, adsorption gas content, reservoir permeability and SRV size were analyzed. Eventually, CBM reservoirs after the volume fracturing stimulation were described more accurately and rationally. This study provides a theoretical basis for a better understanding of the CBM migration laws and an approach to evaluating and developing CBM reservoirs efficiently and rationally.

Status of the CBM experiment

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Heuser Johann M.

2015-01-01

Full Text Available The Compressed Baryonic Matter (CBM experiment at the Facility for Anti-Proton and Ion Research (FAIR will explore the phase diagram of strongly interacting matter at highest net baryon densities and moderate temperatures. The CBM physics program will be started with beams delivered by the SIS 100 synchrotron, providing energies from 2 to 11 GeV/nucleon for heavy nuclei, up to 14 GeV/nucleon for light nuclei, and 29 GeV for protons. The highest net baryon densities will be explored with ion beams up to 45 GeV/nucleon energy delivered by SIS 300 in the next stage of FAIR. Collision rates up to 107 per second are required to produce very rare probes with unprecedented statistics in this energy range. Their signatures are complex. These conditions call for detector systems designed to meet the extreme requirements in terms of rate capability, momentum and spatial resolution, and a novel DAQ and trigger concept which is not limited by latency but by throughput. The article discusses the development status of the CBM sub-systems for charged particle tracking, vertex detection, electron/muon identification, hadron/time-of-flight measurement, electromagnetic and zero-degree calorimetry, in terms of prototypes and expected physics performance. The concept and development status of CBM’s central detector, the Silicon Tracking System STS are presented in somewhat more detail.

Análise da dinâmica espacial da ocupação das terras e seus conflitos de uso no perímetro urbano de Santa Maria - RS (1975 - 2002 Spatial dynamic analysis of the land occupation and their conflicts of use in the urban perimiter of Santa Maria - RS (1975 - 2002

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Fabrício de Araújo Pedron

2006-12-01

Full Text Available As cidades brasileiras, em escala variável, têm apresentado problemas resultantes do uso indevido do espaço urbano, principalmente, em relação aos recursos naturais. Neste caso, o estudo da dinâmica de uso das terras é importante na compreensão dos processos ocorridos no ambiente urbano. O objetivo deste trabalho foi analisar a dinâmica espacial e temporal de ocupação das terras em áreas urbanas de Santa Maria - RS, determinando seus conflitos de uso através do Sistema de Avaliação do Potencial de Uso Urbano das Terras (SAPUT, considerando informações do período de 1975 a 2002. O uso urbano das terras cresceu de 9%, em 1975, para 33%, em 2002. Os conflitos de uso das terras aumentaram de 19%, em 1975, para 37%, em 1995, reduzindo para 33% em 2002. Os principais problemas de uso indevido das terras se relacionam à fragilidade do material geológico e do recurso solo para uso em construções e agricultura urbana.The Brazilian cities have been facing problems due to the improper use of the urban space, mainly, related to the natural resources. In this case, the study of the dynamics of land use is important in the understanding of the processes occured in the urban environment. This research was aimed at analysing the space and temporal dynamics of land occupation in urban areas of Santa Maria - RS, Brazil, determining the conflicts of the land use through the Urban Land Use Potencial System (SAPUT, considering information from 1975 to 2002. The urban land use raised from 9% in 1975 to 33% in 2002. The conflicts of land use have increased from 19% in 1975, to 37% in 1995, reducing to 33% in 2002. The main problems of the improper land use are linked to the fragility of the geological material and soil resource when used for constructions and urban agriculture.

PRÁTICAS AMBIENTALMENTE CORRETAS EM MEIOS DE HOSPEDAGEM: um estudo sobre a percepção ambiental e perfil dos gestores hoteleiros de Santa Vitória do Palmar/RS

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Siuza Monteiro Guedes

2017-09-01

Full Text Available Este estudo foi realizado no município de Santa Vitória do Palmar, RS, teve por objetivo analisar a percepção das práticas ambientalmente corretas de gestão ambiental e de economia de recursos naturais entre os gestores do setor de hospedagem do Município de Santa Vitória do Palmar. Trata-se de um estudo qualiquantitavo de caráter exploratório, representativo e participante, com aplicação de instrumento de coleta de dados, realizado no período de novembro de 2016 a março de 2017 em empreendimentos do setor de hoteleiro e extra-hoteleiro, na cidade sede do Município e em três dos balneários marítimos do mesmo. Como principal resultado pode ser destacado a falta de planos de gestão ambiental dos empreendimentos pesquisados. O estudo se justifica uma vez que não foram encontrados estudos similares.

A Combination of CD28 (rs1980422 and IRF5 (rs10488631 Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study.

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Lucia Vernerova

Full Text Available The aim of the study was to analyse genetic architecture of RA by utilizing multiparametric statistical methods such as linear discriminant analysis (LDA and redundancy analysis (RDA.A total of 1393 volunteers, 499 patients with RA and 894 healthy controls were included in the study. The presence of shared epitope (SE in HLA-DRB1 and 11 SNPs (PTPN22 C/T (rs2476601, STAT4 G/T (rs7574865, CTLA4 A/G (rs3087243, TRAF1/C5 A/G (rs3761847, IRF5 T/C (rs10488631, TNFAIP3 C/T (rs5029937, AFF3 A/T (rs11676922, PADI4 C/T (rs2240340, CD28 T/C (rs1980422, CSK G/A (rs34933034 and FCGR3A A/C (rs396991, rheumatoid factor (RF, anti-citrullinated protein antibodies (ACPA and clinical status was analysed using the LDA and RDA.HLA-DRB1, PTPN22, STAT4, IRF5 and PADI4 significantly discriminated between RA patients and healthy controls in LDA. The correlation between RA diagnosis and the explanatory variables in the model was 0.328 (Trace = 0.107; F = 13.715; P = 0.0002. The risk variants of IRF5 and CD28 genes were found to be common determinants for seropositivity in RDA, while positivity of RF alone was associated with the CTLA4 risk variant in heterozygous form. The correlation between serologic status and genetic determinants on the 1st ordinal axis was 0.468, and 0.145 on the 2nd one (Trace = 0.179; F = 6.135; P = 0.001. The risk alleles in AFF3 gene together with the presence of ACPA were associated with higher clinical severity of RA.The association among multiple risk variants related to T cell receptor signalling with seropositivity may play an important role in distinct clinical phenotypes of RA. Our study demonstrates that multiparametric analyses represent a powerful tool for investigation of mutual relationships of potential risk factors in complex diseases such as RA.

A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study.

Science.gov (United States)

Vernerova, Lucia; Spoutil, Frantisek; Vlcek, Miroslav; Krskova, Katarina; Penesova, Adela; Meskova, Milada; Marko, Andrea; Raslova, Katarina; Vohnout, Branislav; Rovensky, Jozef; Killinger, Zdenko; Jochmanova, Ivana; Lazurova, Ivica; Steiner, Guenter; Smolen, Josef; Imrich, Richard

2016-01-01

The aim of the study was to analyse genetic architecture of RA by utilizing multiparametric statistical methods such as linear discriminant analysis (LDA) and redundancy analysis (RDA). A total of 1393 volunteers, 499 patients with RA and 894 healthy controls were included in the study. The presence of shared epitope (SE) in HLA-DRB1 and 11 SNPs (PTPN22 C/T (rs2476601), STAT4 G/T (rs7574865), CTLA4 A/G (rs3087243), TRAF1/C5 A/G (rs3761847), IRF5 T/C (rs10488631), TNFAIP3 C/T (rs5029937), AFF3 A/T (rs11676922), PADI4 C/T (rs2240340), CD28 T/C (rs1980422), CSK G/A (rs34933034) and FCGR3A A/C (rs396991), rheumatoid factor (RF), anti-citrullinated protein antibodies (ACPA) and clinical status was analysed using the LDA and RDA. HLA-DRB1, PTPN22, STAT4, IRF5 and PADI4 significantly discriminated between RA patients and healthy controls in LDA. The correlation between RA diagnosis and the explanatory variables in the model was 0.328 (Trace = 0.107; F = 13.715; P = 0.0002). The risk variants of IRF5 and CD28 genes were found to be common determinants for seropositivity in RDA, while positivity of RF alone was associated with the CTLA4 risk variant in heterozygous form. The correlation between serologic status and genetic determinants on the 1st ordinal axis was 0.468, and 0.145 on the 2nd one (Trace = 0.179; F = 6.135; P = 0.001). The risk alleles in AFF3 gene together with the presence of ACPA were associated with higher clinical severity of RA. The association among multiple risk variants related to T cell receptor signalling with seropositivity may play an important role in distinct clinical phenotypes of RA. Our study demonstrates that multiparametric analyses represent a powerful tool for investigation of mutual relationships of potential risk factors in complex diseases such as RA.

Component database development for the CBM experiment

International Nuclear Information System (INIS)

Akishina, E.P.; Alexandrov, E.I.; Alexandrov, I.N.; Filozova, I.A.; Ivanov, V.V.; Friese, V.

2015-01-01

This paper presents the implementation of the component database for the CBM experiment. The considered database is designed to effectively manage a large number of components for different CBM detectors during their manufacture, installation and operation. This database contains information about the production company, quality indicators, including test results, information on the whereabouts of the component and its status. A functional model, a design of the database schema, a description of tables and catalogs as well as a graphical user interface system are shown. [ru

Association of rs6265 and rs2030324 polymorphisms in brain-derived neurotrophic factor gene with Alzheimer's disease: a meta-analysis.

Directory of Open Access Journals (Sweden)

Yan Lin

Full Text Available BACKGROUND: The association between polymorphisms rs6265 and rs2030324 in brain-derived neurotrophic factor (BDNF and Alzheimer's disease (AD has been widely reported, but the results remain controversial. METHODS: A comprehensive search of Pubmed, Web of Science, China National Knowledge Infrastructure (CNKI, Wanfang Med Online and China Biology Medical literature database (CBM was performed. Pooled odds ratios (ORs with 95% confidence intervals (CIs were calculated using fixed or random-effects models. We excluded the studies with OR>3.0 or OR<0.3 for sensitive analysis. Subgroup analysis by ethnicity, form of AD and gender was carried out. Meta-regression was conducted to explore the potential sources of between-study heterogeneity. RESULTS: 29 articles with 7548 cases and 7334 controls concerning rs6265 and 22 articles with 5796 cases and 5706 controls concerning rs2030324 were included in this meta-analysis. The combined evidence suggested rs6265 contributing significantly to the increased risk of AD in females (codominant: fixed-effects model (FEM: OR = 1.13, 95% CI = 1.04-1.23; dominant: FEM: OR = 1.17, 95% CI = 1.05-1.31, especially for Caucasian females (codominant: FEM: OR = 1.18, 95% CI = 1.03-1.34; dominant: FEM: OR = 1.18, 95% CI = 1.01-1.37 and female late-onset Alzheimer's disease (LOAD patients (codominant: FEM: OR = 1.22, 95% CI = 1.05-1.41; dominant: FEM: OR = 1.23, 95% CI = 1.03-1.46. No evidence indicated an association between rs2030324 with AD in codominant (random-effects model (REM: OR = 1.06, 95% CI = 0.89-1.26 and dominant (REM: OR = 1.05, 95% CI = 0.86-1.27 models. CONCLUSION: This meta-analysis suggested A allele of rs6265 might increase the risk of AD in Caucasian females and female LOAD patients. In addition, no evidence indicated an association between rs2030324 with AD. Further studies are needed to confirm these results.

QR Code Mobile sebagai Pendukung Rekam Medik Berkas Rawat Jalan RS. St. Elisabeth Semarang

Directory of Open Access Journals (Sweden)

Aldhi Ari Kurniawan

2018-01-01

Full Text Available Medical record play important role in order to improve hospital healthcare quality. Medical record must provide proper, fast, and relevant data. Current medical records documentation is manual based in mean the documents are available in notes and document maps. There is no integration among the document, and it can caused a misunderstanding among hospital stakeholder such as doctor or nurse and also duplicated data. QR code is one of alternative to handle completeness file, searching document, and store all document. The combination between QR code, web and mobile platform can handle the problem faced by hospital stakeholder. In testing phase, the proposed system can handle medical record problem in RS. St. Elisabeth. Average of respondent, more than 50% state that sistem is good to handle tracking record, completeness file, and store.

Macroinvertebrados bentônicos como indicadores de qualidade de água na Barragem Santa Bárbara, Pelotas, RS, Brasil Zoobenthics as indicators of the water quality in the Santa Bárbara Dam, Pelotas, RS, Brazil

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Sérgio Renato Noguez Piedras

2006-04-01

Full Text Available O objetivo deste trabalho foi estudar o impacto de dois afluentes da barragem Santa Bárbara sobre o ambiente da mesma, utilizando a ocorrência de invertebrados bentônicos e características químicas da água. Durante nove meses foram realizadas coletas e análises da água e de invertebrados bentônicos nos afluentes Sanga da Barbuda e Sanga do Passo do Cunha e também no interior da bacia de acumulação da barragem. Os resultados mostram que, embora a Sanga da Barbuda e a Sanga do Passo do Cunha apresentem características químicas abaixo do recomendável, no limite aceitável pela legislação que determina os padrões de qualidade da água para abastecimento público, estes afluentes estão, ainda, sendo diluídos de forma satisfatória na bacia de acumulação da barragem. O estudo das relações entre variáveis químicas e invertebrados bentônicos mostra haver correlação significativa entre os baixos níveis de oxigênio dissolvido e a presença de Oligochaeta, sendo que o aumento do número de Oligochaeta indica uma situação de anoxia na barragem Santa Bárbara.The objective of this work was to study the impact of two tributaries from the Santa Bárbara Dam on this environment using the occurrence of zoobenthics and some water chemical characteristics. Monthly gathering and analysis from the water and zoobenthics were done during nine months in the tributaries Sanga da Barbuda and Sanga Passo do Cunha as well as in the inner part of the accumulation basin in the Santa Barbara dam. The results demonstrate that, though Sanga da Barbuda and Sanga Passo do Cunha present chemical characteristics lower than the recommended but still in the limits acceptable by the law that regulates the water quality standards for the supply, these tributaries are being diluted in a satisfactory way in the accumulation basin in the Santa Barbara dam. The study of the relations between chemical variables and zoobenthics show a significant correlation

Requirements for the Silicon Tracking System of CBM at FAIR

International Nuclear Information System (INIS)

Heuser, Johann M.; Deveaux, M.; Muentz, C.; Stroth, J.

2006-01-01

The Compressed Baryonic Matter (CBM) experiment at the future Facility for Antiproton and Ion Research (FAIR) in Darmstadt will systematically study dense baryonic matter created in collisions of intense heavy-ion beams with nuclear targets. The research addresses current questions of strong-interaction physics as confinement in normal nuclear matter, chiral symmetry restoration in deconfined matter at high temperatures and densities, and the search for the critical end-point of the phase boundary. With beams of ions as heavy as Au and U, energies up to 45GeV/nucleon and intensities up to 10 12 ions per pulse, FAIR will enable CBM to probe the phase diagram of quantum chromo dynamics (QCD) in a region poorly known, while being complementary to current and future research programmes at RHIC and LHC. The CBM experiment is planned as a fixed-target spectrometer optimized for the detection of rare probes. Among these are open charm and low-mass vector mesons, important observables for the initial energetic and dense phase of the collisions. The experimental concept and challenge is to accomplish charged particle tracking in the high-multiplicity, high-radiation collision environment. This will be realized exclusively with a silicon tracking detector system installed in a strong magnetic dipole field directly behind the target. Key to the physics of CBM and benchmark for the tracking is the reconstruction of short-lived charmed mesons that puts high demands on the silicon detectors. The article presents a conceptual design of the CBM experiment with emphasis on the silicon tracking system. Requirements for silicon microstrip and pixel detectors and their arrangement in the tracker are discussed in relation to important physics observables addressed by CBM

LEVANTAMENTO PARASITOLÓGICO EM Hoplias Malabaricus, Bloch, (1794 (TRAIRA DE ÁGUAS DA REGIÃO DE SANTA MARIA - RS

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Ana Maria Weiblen

1992-08-01

Full Text Available No presente trabalho estudou-se os parasitos encontrados em 139 traíras coletadas nas diferentes estações do ano em lagoas e açudes do município de Santa Maria, RS. Os objetivos deste levantamento foram: determinar a localização preferencial dos parasites no hospedeiro, relacionar a prevalência dos parasites com as estações do ano e identificar os mesmos a nível de gênero e se possível espécie. Dos 139 peixes necropsiados, 2812 parasites foram coletados ficando assim distribuídos: 469 na primavera, 921 no verão, 482 no outono e 940 no inverno. Destes 2812 parasitos, 1637 foram nematódeos pertencentes as seguintes espécies: Contracaecum sp, Parasseuratum soaresi, Paracappilaria piscicola, Guyanema baudi, Spirocamallanus hilarii, Procamallanus peraccuratus e nematódeos não identificados; 931 trematódeos pertencentes a Ithyoclinostomulum dimorphum, Tylodelphylus sp. 1, Dendrorchis sp, Clinostomum sp e Halipegus overstreeti; 106 acantocéfalos pertencentes a Quadrigyrus machadoi; 138 microcrustáceos do gênero Ergasilus e 20 argulídeos do gênero Dolops.

Study of the characteristics of gas electron multipliers for the FAIR experiment CBM

International Nuclear Information System (INIS)

Biswas, S.; Abuhoza, A.; Frankenfeld, U.; Hehner, J.; Schmidt, C.J.; Traeger, M.; Schmidt, H.R.; Colafranceschi, S.; Marinov, A.; Sharma, A.

2011-01-01

The Compressed Baryonic Matter (CBM) experiment at the future Facility for Antiproton and Ion Research (FAIR) in Darmstadt, Germany will use proton and heavy ion beams to study matter at extreme conditions. The CBM experiment at FAIR is designed to explore the QCD phase diagram in the region of high baryon densities. With CBM we will enter a new era of nuclear matter research by measuring rare diagnostic probes never observed before at FAIR energies, and thus CBM has a unique discovery potential. This will only be possible with the application of advanced instrumentation, including highly segmented and fast gaseous detectors

Selection of strategic replacement areas for CBM exploration and development in China

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Longyi Shao

2015-03-01

Full Text Available At present, the increase in proved reserves and production of coalbed methane (CBM in China depends mainly on several CBM bases in the southern Qinshui Basin and in the eastern margin of the Ordos Basin. Therefore, it is urgent to find new batches of exploration and development strategic replacement areas. For this purpose, we investigated the resources, reservoir properties, preservation conditions, and development conditions of CBM in China, and put forward eight general factors and four critical factors that can be used in establishing selection criteria of strategic replacement areas for affecting the CBM exploration and development in China. The eight general factors are resource abundance, coalbed thickness, gas content, original permeability, burial depth, hydrogeological conditions, coalbed depositional environment, and landforms, and the four critical factors include genetic type, stability type, later reservoir reformation, and damage degree of coal structure. Comparison shows that the low-rank coal area in the northwestern area, the northeastern medium-low rank coal area, and the southwestern medium-high rank and structurally-complex coal area are the major replacement areas for CBM following the northern area of China. Key factors affecting CBM enrichment in each of the three key areas, respectively, are: a genetic type and stability of coal seams, b genetic type and reconstruction of the reservoir by volcanic intrusion, and c stability of coal seams and damage degree of coal structure. Based on these factors, a system for selection and evaluation of strategic replacement areas for CBM development was established. Fifteen blocks in the above three areas were evaluated by using multi-layered fuzzy mathematics, selecting eight favorable areas and seven relatively favorable areas that contain 1.8 trillion m3 of predicted CBM geological resources. The eight favorable areas include the Wucaiwan-Dajing coal exploration area in the Zhundong

The starch-binding domain family CBM41 - an in silico analysis of evolutionary relationships

DEFF Research Database (Denmark)

Janeček, Štefan; Majzlová, Katarína; Svensson, Birte

2017-01-01

Within the CAZy database, there are 81 carbohydrate-binding module (CBM) families. A CBM represents a non-catalytic domain in a modular arrangement of glycoside hydrolases (GHs). The present in silico study has been focused on starch-binding domains from the family CBM41 that are usually part...

Převodník Ethernet na RS-232

OpenAIRE

Dreiseitel, Jiří

2012-01-01

Práce je věnována problematice konstrukce převodníku Ethernet na RS-232 za pomocí jednočipového mikrokontroléru. Cílem je seznámit čtenáře se síťovou technologií Ethernet a technologií pro sériový přenos založený na protokolu RS-232 a zároveň s technologií vestavěných systémů pro konstrukci zařízení. Součástí práce je kompletní návrh převodníku Ethernet na RS-232 včetně návrhu a implementace firmware v jazyce C za využití LwIP TCP/IP stacku. Převodník je postaven na základě vývojového kitu ST...

OCORRÊNCIA E DURAÇÃO DAS TEMPERATURAS MÍNIMAS DIÁRIAS DO AR PREJUDICIAIS À FECUNDAÇÃO DAS FLORES DO ARROZ EM SANTA MARIA, RS: .II - ESTIMATIVA DO NÚMERO DIÁRIO DE HORAS COM TEMPERATURAS BAIXAS

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Valduino Estefanel

1991-12-01

Full Text Available O presente trabalho objetivou testar os modelos analíticos utilizados por ANGELOCCI et al (1979, HELDWEIN (1983 e os propostos com ajustes para o verão de Santa Maria (Santa Maria, I, II e III para estimar o número diário de horas com temperatura do ar ≤ 10, 11, 12, 13, 14, 15, 16 e 17,0°C, para os meses de dezembro, Janeiro, fevereiro e março para Santa Maria, RS. A comparação entre os valores obtidos diretamente dos termogramas e os estimados por cinco modelos analíticos (ANGELOCCI et al, 1979; HELDWEIN,1983; Santa Maria I, II e III foi feita em função dos valores médios diários de horas dos dias com temperaturas baixas, coeficientes de determinação, linear e angular da equação de 1° grau entre os valores reais e os estimados. Verifica-se que é possível estimar, com precisão satisfatória, o número diário de horas com temperatura do ar ≤ 17, 16, 15, 14, 13 e 12,0°C, utilizando os modelos analíticos de ANGELOCCI et al (1979 e o Santa Maria III.

Tratamento de dados climáticos de Santa Maria, RS, para análise de desempenho térmico de edificações

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Giane de Campos Grigoletti

Full Text Available Resumo O tratamento e a disponibilização de dados climáticos para projeto de edificações são importantes para seu desempenho térmico e eficiência energética. O Ano Climático de Referência (TRY, o Ano Meteorológico Típico (TMY2, a carta bioclimática, arquivos EPW e CVS, diagrama de ventos e o dia típico de projeto são os tratamentos mais comuns. Para Santa Maria - RS, algumas destas sistematizações já existiam, porém para um período de oito anos. O objetivo do estudo foi tratar e analisar dados climáticos para Santa Maria, complementando estudos anteriores, ampliando a base de dados para doze anos e atualizando seu tratamento. O estudo baseou-se em bibliografia científica e metodologias que vêm sendo empregadas por vários pesquisadores. Os resultados apontam maior desconforto por frio. A radiação solar é bem distribuída ao longo do ano, indicando aquecimento solar passivo, no inverno, e sombreamento, no verão. O arquivo TMY2 gerado no estudo tem comportamento similar ao TRY-INMET (2012 e apresenta diferenças mais significativas quando comparado ao SWERA. Observou-se a importância das orientações norte e nordeste, para aquecimento solar, e leste, para ventilação. Os métodos apresentados podem ser aplicados a outras localidades com dados horários disponíveis.

On-line reconstruction algorithms for the CBM and ALICE experiments

International Nuclear Information System (INIS)

Gorbunov, Sergey

2013-01-01

This thesis presents various algorithms which have been developed for on-line event reconstruction in the CBM experiment at GSI, Darmstadt and the ALICE experiment at CERN, Geneve. Despite the fact that the experiments are different - CBM is a fixed target experiment with forward geometry, while ALICE has a typical collider geometry - they share common aspects when reconstruction is concerned. The thesis describes: - general modifications to the Kalman filter method, which allows one to accelerate, to improve, and to simplify existing fit algorithms; - developed algorithms for track fit in CBM and ALICE experiment, including a new method for track extrapolation in non-homogeneous magnetic field. - developed algorithms for primary and secondary vertex fit in the both experiments. In particular, a new method of reconstruction of decayed particles is presented. - developed parallel algorithm for the on-line tracking in the CBM experiment. - developed parallel algorithm for the on-line tracking in High Level Trigger of the ALICE experiment. - the realisation of the track finders on modern hardware, such as SIMD CPU registers and GPU accelerators. All the presented methods have been developed by or with the direct participation of the author.

Status of the CBM micro vertex detector

Energy Technology Data Exchange (ETDEWEB)

Koziel, Michal [Goethe-Universitaet Frankfurt (Germany); Collaboration: CBM-MVD-Collaboration

2015-07-01

The fixed-target experiment CBM at FAIR will explore the phase diagram of strongly interacting matter in the regime of highest net baryon densities with numerous probes, among them open charm. For the reconstruction of open charm hadrons with the CBM experiment a Micro Vertex Detector (MVD) with an excellent spatial resolution of the secondary decay vertex is required. Hence, a material budget of a few 0.1% X0 is mandatory for the individual detector stations positioned downstream in close vicinity to the target. To reduce multiple scattering, the MVD operates in vacuum, which poses challenging requirements on both, the power dissipation of the sensors and the integration concept. Here one should mention the selection of high-performance materials providing the mechanical support and cooling for the 0.05 mm thin sensors, establishing the sensor quality assessment procedures as well as defining the sensor integration. In addition, a substantial progress with respect to sensor development will be reported, mainly to the studies on their radiation hardness. Also, the 2nd generation of the sensor control and read-out based on TRBv3 standard has been commissioned. In this contribution we highlight several activities that have been successfully accomplished, which enable us to define the start version of the CBM MVD.

Quench calculations for the superconducting dipole magnet of CBM experiment at FAIR

International Nuclear Information System (INIS)

Kurilkin, P.; Akishin, P.; Bychkov, A.; Gusakov, Yu.; Ladygin, V.; Malakhov, A.; Shabunov, A.; Toral, F.; Floch, E.; Moritz, G.; Ramakers, H.; Senger, P.; Szwangruber, P.

2016-01-01

The scientific mission of the Compressed Baryonic Matter (CBM) experiment is the study of the nuclear matter properties at the high baryon densities in heavy ion collisions at the Facility of Antiproton and Ion Research (FAIR) in Darmstadt. The 5.15 MJ superconducting dipole magnet will be used in the silicon tracking system of the CBM detector. It will provide a magnetic field integral of 1 Tm which is required to obtain a momentum resolution of 1% for the track reconstruction. This paper presents quench modeling and evaluation of candidate protection schemes for the CBM dipole magnet. Two quench programs based on finite-difference method were used in simulation. One of them is currently used at GSI, and the other based on CIEMAT (Madrid, Spain) was modified to perform quench calculation for the CBM magnet. (paper)

Geração de imagem georreferenciada do município de Santa Maria utilizando imagem de satélite e sistemas de informações geográficas Generation of georreferenced image of Santa Maria county utilizing satellite image and geographic information systems

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Edson Luís Piroli

1999-09-01

Full Text Available O trabalho foi desenvolvido no Laboratório de Sensoriamento Remoto e Geoprocessamento, do Departamento de Engenharia Rural, da Universidade Federal de Santa Maria, tendo como objetivo a criação de uma imagem georreferenciada do Município de Santa Maria - RS. Foram utilizados para o seu desenvolvimento os sistemas de informações geográficas IDRISI e SITER e imagens do satélite Landsat 5 - TM. Os procedimentos para a obtenção da imagem georreferenciada foram basicamente de elaboração de composição falsa-cor, georreferência e corte da área abrangida pelo Município de Santa Maria. Os aplicativos SIG utilizados e as imagens de satélite foram suficientes e eficazes para a elaboração de imagem georreferenciada do município de Santa Maria.This work was developed at the laboratory of Remote Sensing and Geoprocessing of Department of Rural Engineering of University Federal of Santa Maria, had as objective the creation of a georreferenced image of Santa Maria county - RS. Made possible the development through the associated by the digital Landsat 5 - TM and they Geographic Information System IDRISI and SITER. The proceedings to again imagery georeferenced were elaborated from the color compositae, georreferencing techniques and the out line municipality boundary. The softwares GIS and the satellite image utilized were effective to reach the main goal of this work.

Characterization of a novel theme C glycoside hydrolase family 9 cellulase and its CBM-chimeric enzymes.

Science.gov (United States)

Duan, Cheng-Jie; Huang, Ming-Yue; Pang, Hao; Zhao, Jing; Wu, Chao-Xing; Feng, Jia-Xun

2017-07-01

In bacterial cellulase systems, glycoside hydrolase family 9 (GH9) cellulases are generally regarded as the major cellulose-degrading factors besides GH48 exoglucanase. In this study, umcel9A, which was cloned from uncultured microorganisms from compost, with the encoded protein being theme C GH9 cellulase, was heterologously expressed in Escherichia coli, and the biochemical properties of the purified enzyme were characterized. Hydrolysis of carboxylmethylcellulose (CMC) by Umcel9A led to the decreased viscosity of CMC solution and production of reducing sugars. Interestingly, cellobiose was the major product when cellulosic materials were hydrolyzed by Umcel9A. Six representative carbohydrate-binding modules (CBMs) from different CBM families (CBM1, CBM2, CBM3, CBM4, CBM10, and CBM72) were fused with Umcel9A at the natural terminal position, resulting in significant enhancement of the binding capacity of the chimeric enzymes toward four different insoluble celluloses as compared with that of Umcel9A. Catalytic activity of the chimeric enzymes against insoluble celluloses, including phosphoric acid-swollen cellulose (PASC), alkali-pretreated sugarcane bagasse (ASB), filter paper powder (FPP), and Avicel, was higher than that of Umcel9A, except for Umcel9A-CBM3. In these chimeric enzymes, CBM4-Umcel9A exhibited the highest activity toward the four tested insoluble celluloses and displayed 4.2-, 3.0-, 2.4-, and 6.6-fold enhanced activity toward PASC, ASB, FPP, and Avicel, respectively, when compared with that of Umcel9A. CBM4-Umcel9A also showed highest V max and catalytic efficiency (k cat /K M ) against PASC. Construction of chimeric enzymes may have potential applications in biocatalytic processes and provides insight into the evolution of the molecular architecture of catalytic module and CBM in GH9 cellulases.

Propensão ao Endividamento no Município de Santa Maria (RS: verificando diferenças em variáveis demográficas e culturais

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Vieira, Kelmara Mendes

2014-12-01

Full Text Available This study tried to investigate, considering regard the individuals’ possible financial difficulties and the importance of indebtedness for economy, the propensity to indebtedness from inhabitants of Santa Maria (RS, with the aim to know the spending’ profile, as well as demographic and cultural variables related to propensity to indebtedness. We conducted a survey research, having sampled 1,046 respondents. The data has been collected through a structured questionnaire composed by two sections, the first section is related to demographic and social respondents’ variables, and also questions about credit and spending, the second one is related to the propensity to indebtedness. With regard to the analysis of results, descriptive statistics has been used to demographic and cultural variables, and ANOVA analysis to evaluate the differences in average between groups. The comparison between groups have shown difference in propensity to indebtedness in relation to marital status, schooling level, occupation, income, religion, age and spending. It can be observed that most groups with more tendency to indebtedness are single and widowers, with lower schooling level (primary and secondary school, with no occupation, low income, with no religion, young people (until 22 years old and who spend more than they earn. In general, this study has shown that inhabitants of Santa Maria can be characterized in a more conservative behavior, showing low level to indebtedness.

Time-based Reconstruction of Free-streaming Data in CBM

Science.gov (United States)

Akishina, Valentina; Kisel, Ivan; Vassiliev, Iouri; Zyzak, Maksym

2018-02-01

Traditional latency-limited trigger architectures typical for conventional experiments are inapplicable for the CBM experiment. Instead, CBM will ship and collect time-stamped data into a readout buffer in a form of a time-slice of a certain length and deliver it to a large computer farm, where online event reconstruction and selection will be performed. Grouping measurements into physical collisions must be performed in software and requires reconstruction not only in space, but also in time, the so-called 4-dimensional track reconstruction and event building. The tracks, reconstructed with 4D Cellular Automaton track finder, are combined into event-corresponding clusters according to the estimated time in the target position and the errors, obtained with the Kalman Filter method. The reconstructed events are given as inputs to the KF Particle Finder package for short-lived particle reconstruction. The results of time-based reconstruction of simulated collisions in CBM are presented and discussed in details.

Time-based MRPC detector response simulations for the CBM time-of-flight system

Energy Technology Data Exchange (ETDEWEB)

Simon, Christian; Herrmann, Norbert [Physikalisches Institut und Fakultaet fuer Physik und Astronomie, Ruprecht-Karls-Universitaet Heidelberg (Germany); Collaboration: CBM-Collaboration

2016-07-01

The design goal of the future Compressed Baryonic Matter (CBM) experiment is to measure rare probes of dense strongly interacting matter with an unprecedented accuracy. Target interaction rates of up to 10 MHz need to be processed by the detector. The time-of-flight (TOF) wall of CBM which should provide hadron identification at particle fluxes of up to a few tens of kHz/cm{sup 2} is composed of high-resolution timing multi-gap resistive plate chambers (MRPCs). Due to the self-triggered digitization and readout scheme of CBM comprising online event reconstruction preparatory Monte Carlo (MC) transport and response simulations including the MRPC array need to be carried out in a time-based fashion. While in an event-based simulation mode interference between MC tracks in a detector volume owing to rate effects or electronics dead time is confined to a single event, time-based response simulations need to take into account track pile-up and interference across events. A proposed time-based digitizer class for CBM-TOF within the CbmRoot software framework is presented.

Event reconstruction for the CBM-RICH prototype beamtest data in 2014

Science.gov (United States)

Adamczewski-Musch, J.; Akishin, P.; Becker, K.-H.; Belogurov, S.; Bendarouach, J.; Boldyreva, N.; Deveaux, C.; Dobyrn, V.; Dürr, M.; Eschke, J.; Förtsch, J.; Heep, J.; Höhne, C.; Kampert, K.-H.; Kochenda, L.; Kopfer, J.; Kravtsov, P.; Kres, I.; Lebedev, S.; Lebedeva, E.; Leonova, E.; Linev, S.; Mahmoud, T.; Michel, J.; Miftakhov, N.; Niebur, W.; Ovcharenko, E.; Patel, V.; Pauly, C.; Pfeifer, D.; Querchfeld, S.; Rautenberg, J.; Reinecke, S.; Riabov, Y.; Roshchin, E.; Samsonov, V.; Schetinin, V.; Tarasenkova, O.; Traxler, M.; Ugur, C.; Vznuzdaev, E.; Vznuzdaev, M.

2017-12-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR facility will investigate the QCD phase diagram at high net baryon densities and moderate temperatures in A+A collisions from 2 to 11 AGeV (SIS100). Electron identification in CBM will be performed by a Ring Imaging Cherenkov (RICH) detector and Transition Radiation Detectors (TRD). A real size prototype of the RICH detector was tested together with other CBM groups at the CERN PS/T9 beam line in 2014. For the first time the data format used the FLESnet protocol from CBM delivering free streaming data. The analysis was fully performed within the CBMROOT framework. In this contribution the data analysis and the event reconstruction methods which were used for obtained data are discussed. Rings were reconstructed using an algorithm based on the Hough Transform method and their parameters were derived with high accuracy by circle and ellipse fitting procedures. We present results of the application of the presented algorithms. In particular we compare results with and without Wavelength shifting (WLS) coating.

CBM collaboration : PTAC bringing companies together to jumpstart complex well technology advance

Energy Technology Data Exchange (ETDEWEB)

Smith, M.

2008-03-15

This article discussed a joint industry project (JIP) established by the Petroleum Technology Alliance Canada (PTAC) to develop technology applications for coalbed methane (CBM) complexes. A minimum of 8 companies will be needed to initiate the JIP when changes to the royalty regime by the Alberta government are expected to take place. It is expected that the CBM JIP will develop and transfer best practices for optimized CBM exploitation through the use of non-vertical well technology. Three tasks have also been outlined for the project's first year: (1) the creation of a website with public and private access modules; (2) the development of a library of detailed well histories that document field experiences; and (3) launching studies into coal fines-contaminated production streams. The development of horizontal drilling techniques is expected to result in improved environmental benefits due to accelerated production procedures and improved pad configurations. The well history library will act as a primary field data source. It is estimated that approximately 20 trillion cubic feet of CBM reserves are available for recovery using known technologies. However, the development of new technologies is expected to result in an estimated 200 Tcf of recoverable CBM reserves. 1 fig.

Polymorphisms of ST2-IL18R1-IL18RAP gene cluster: a new risk for autoimmune thyroid diseases.

Science.gov (United States)

Wang, X; Zhu, Y F; Li, D M; Qin, Q; Wang, Q; Muhali, F S; Jiang, W J; Zhang, J A

2016-02-01

Interleukin 33 (IL33) / ST2 pathway and ST2-interlukin18 receptor1-interlukin18 receptor accessory protein (ST2-IL18R1-IL18RAP) gene cluster have been involved in many autoimmune diseases but few report in autoimmune thyroid diseases (AITD). In this study, we investigated whether polymorphisms of IL33, ST2, IL18R1, and IL18RAP are associated with Graves' disease (GD) and Hashimoto's thyroiditis (HT), two major forms of AITD, among a Chinese population. A total of 11 SNPs were explored in a case-control study including 417 patients with GD, 250 HT patients and 301 controls, including rs1929992, rs10975519, rs10208293, rs6543116, rs1041973, rs3732127, rs11465597, rs1035130, rs2293225, rs1035127, rs917997 of IL 33, ST2-IL18R1-IL18RAP gene cluster. Genotyping of these SNPs was performed using matrix-assisted laser desorption / ionization-time-of-flight mass spectrometer (MALDI-TOF-MS) platform from Sequenom. The frequencies of allele A and AA+AG genotype of rs6543116 (ST2) in HT patients were significantly increased compared with those of the controls (P = 0.029/0.021, OR = 1.31/1.62). And in another SNP rs917997, AA+AG genotype presented an increased frequency in HT subjects compared with controls (P = 0.046, OR = 1.53). Furthermore, the haplotype GAGCCCG from ST2-IL18R1-IL18RAP gene cluster (rs6543116, rs1041973, rs1035130, rs3732127, rs1035127, rs2293225, rs917997) was associated with increased susceptibility to GD with an OR of 2.03 (P = 0.022, 95% CI = 1.07-3.86). Some SNPs of ST2-IL18R1-IL18RAP gene cluster might increase the risk of susceptibility of HT and GD in Chinese Han population. © 2015 John Wiley & Sons Ltd.

Internal monitoring of GBTx emulator using IPbus for CBM experiment

Science.gov (United States)

Mandal, Swagata; Zabolotny, Wojciech; Sau, Suman; Chkrabarti, Amlan; Saini, Jogender; Chattopadhyay, Subhasis; Pal, Sushanta Kumar

2015-09-01

The Compressed Baryonic Matter (CBM) experiment is a part of the Facility for Antiproton and Ion Research (FAIR) in Darmstadt at GSI. In CBM experiment a precisely time synchronized fault tolerant self-triggered electronics is required for Data Acquisition (DAQ) system in CBM experiments which can support high data rate (up to several TB/s). As a part of the implementation of the DAQ system of Muon Chamber (MUCH) which is one of the important detectors in CBM experiment, a FPGA based Gigabit Transceiver (GBTx) emulator is implemented. Readout chain for MUCH consists of XYTER chips (Front end electronics) which will be directly connected to detector, GBTx emulator, Data Processing Board (DPB) and First level event selector board (FLIB) with backend software interface. GBTx emulator will be connected with the XYTER emulator through LVDS (Low Voltage Differential Signalling) line in the front end and in the back end it is connected with DPB through 4.8 Gbps optical link. IPBus over Ethernet is used for internal monitoring of the registers within the GBTx. In IPbus implementation User Datagram Protocol (UDP) stack is used in transport layer of OSI model so that GBTx can be controlled remotely. A Python script is used at computer side to drive IPbus controller.

The CBM first-level event selector input interface

Energy Technology Data Exchange (ETDEWEB)

Hutter, Dirk; Lindenstruth, Volker [Frankfurt Institute for Advanced Studies, Goethe University, Frankfurt (Germany); Collaboration: CBM-Collaboration

2015-07-01

The CBM First-level Event Selector (FLES) is the central event selection system of the upcoming CBM experiment at FAIR. Designed as a high-performance computing cluster, its task is an online analysis of the physics data at a total data rate exceeding 1 TByte/s. To allow efficient event selection, the FLES has to combine the data from all given input links to self-contained, overlapping processing intervals and distribute them to compute nodes. This task can be performed efficiently by partitioning the detector data streams into specialized containers. The FLES Interface Board (FLIB), implemented as a custom FPGA board, receives these containers via optical links, prepares them for subsequent interval building, and transfers the data via DMA to the PC's memory. A prototype of the FLIB has been implemented. The inclusion of features foreseen for other parts of the CBM read-out chain allows the evaluation of the interval building concept. Performance studies demonstrated high read-out bandwidth with low overhead. In addition, the FLIB has been used successfully as a readout device in test-beams and lab setups. An overview of the FLES Interface Board as well as results from latest studies is presented.

The rural after the exodus: the implications of the depopulation of the fields in Arroio do Só - Santa Maria/RS, Brazil O rural depois do êxodo: as implicações do despovoamento dos campos no distrito de Arroio do Só, município de Santa Maria/RS, Brasil

Directory of Open Access Journals (Sweden)

Fabricio Teló

2012-01-01

Full Text Available This study aims to understand the sociospatial transformations resulting from the depopulation of the fields and their effects on the rural landscape of Arroio do Só in Santa Maria - RS. To this end, we attempted to identify changes in the way of life of rural people, their activities and relationships and understand how this process has occurred, its causes and its impact on quality of life and social structure of the population that remained in place. The discussion on the modernization of agriculture is key to understanding this process. This district was chosen as a research site because it is a town that, in the past, had a very big socioeconomic dynamism, and now, according to the bankruptcy of several companies and the consequent emigration of much of the population, the sociospatial dynamic has changed. It was collected data from a secondary source of FIBGE and FEE in order to periodize population dynamics of the district, county and state. The qualitative research was conducted through interviews with the subjects in the field and their representatives, with the help of the Field DiaryEste trabalho tem por objetivo apreender as transformações socioespaciais decorrentes do processo de despovoamento dos campos e seus reflexos sobre a paisagem rural do distrito de Arroio do Só, em Santa Maria – RS. Para isso buscou-se identificar as mudanças no modo de vida da população rural, suas atividades e relações e compreender como se deu esse processo, suas causas e suas repercussões na qualidade de vida e na estrutura social da população que permaneceu no local. A discussão sobre a modernização da agricultura é fundamental para a compreensão desse processo. Esse distrito foi escolhido como local de pesquisa por ser uma localidade que, no passado tinha um grande dinamismo socioeconômico, e agora, em função das falências das várias empresas e da consequente emigração de grande parte da população, a dinâmica socioespacial

Fast reconstruction of multi-strange hyperons in the CBM experiment

Energy Technology Data Exchange (ETDEWEB)

Vassiliev, Iouri [GSI, Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Collaboration: CBM-Collaboration

2015-07-01

The main goal of the CBM experiment is to study the behaviour of nuclear matter at very high baryonic density in which the transition to a deconfined and chirally restored phase is expected to happen. One of the promissing signatures of this new state is the enhanced production of multi-strange particles, therefore the reconstruction of multi-strange hyperons is essential for the understanding of the heavy ion collision dynamics. Another experimental challenge of the CBM experiment is online selection of open charm particles via the displaced vertex of the hadronic decay, Charmonium and low mass vector mesons in the environment of a heavy-ion collision. This task requires fast and efficient track reconstruction algorithms, primary vertex finder and particles finder. Results of feasibility studies of the multi-strange hyperons in the CBM experiment are presented.

The Development of a Gas-Liquid Two-Phase Flow Sensor Applicable to CBM Wellbore Annulus.

Science.gov (United States)

Wu, Chuan; Wen, Guojun; Han, Lei; Wu, Xiaoming

2016-11-18

The measurement of wellbore annulus gas-liquid two-phase flow in CBM (coalbed methane) wells is of great significance for reasonably developing gas drainage and extraction processes, estimating CBM output, judging the operating conditions of CBM wells and analyzing stratum conditions. Hence, a specially designed sensor is urgently needed for real-time measurement of gas-liquid two-phase flow in CBM wellbore annulus. Existing flow sensors fail to meet the requirements of the operating conditions of CBM wellbore annulus due to such factors as an inapplicable measurement principle, larger size, poor sealability, high installation accuracy, and higher requirements for fluid media. Therefore, based on the principle of a target flowmeter, this paper designs a new two-phase flow sensor that can identify and automatically calibrate different flow patterns of two-phase flows. Upon the successful development of the new flow sensor, lab and field tests were carried out, and the results show that the newly designed sensor, with a measurement accuracy of ±2.5%, can adapt to the operating conditions of CBM wells and is reliable for long-term work.

The Development of a Gas–Liquid Two-Phase Flow Sensor Applicable to CBM Wellbore Annulus

Science.gov (United States)

Wu, Chuan; Wen, Guojun; Han, Lei; Wu, Xiaoming

2016-01-01

The measurement of wellbore annulus gas–liquid two-phase flow in CBM (coalbed methane) wells is of great significance for reasonably developing gas drainage and extraction processes, estimating CBM output, judging the operating conditions of CBM wells and analyzing stratum conditions. Hence, a specially designed sensor is urgently needed for real-time measurement of gas–liquid two-phase flow in CBM wellbore annulus. Existing flow sensors fail to meet the requirements of the operating conditions of CBM wellbore annulus due to such factors as an inapplicable measurement principle, larger size, poor sealability, high installation accuracy, and higher requirements for fluid media. Therefore, based on the principle of a target flowmeter, this paper designs a new two-phase flow sensor that can identify and automatically calibrate different flow patterns of two-phase flows. Upon the successful development of the new flow sensor, lab and field tests were carried out, and the results show that the newly designed sensor, with a measurement accuracy of ±2.5%, can adapt to the operating conditions of CBM wells and is reliable for long-term work. PMID:27869708

CBM first-level event selector input interface

Energy Technology Data Exchange (ETDEWEB)

Hutter, Dirk [Frankfurt Institute for Advanced Studies, Goethe University, Frankfurt (Germany); Collaboration: CBM-Collaboration

2016-07-01

The CBM First-level Event Selector (FLES) is the central event selection system of the upcoming CBM experiment at FAIR. Designed as a high-performance computing cluster, its task is an online analysis of the physics data at a total data rate exceeding 1 TByte/s. To allow efficient event selection, the FLES performs timeslice building, which combines the data from all given input links to self-contained, overlapping processing intervals and distributes them to compute nodes. Partitioning the input data streams into specialized containers allows to perform this task very efficiently. The FLES Input Interface defines the linkage between FEE and FLES data transport framework. Utilizing a custom FPGA board, it receives data via optical links, prepares them for subsequent timeslice building, and transfers the data via DMA to the PC's memory. An accompanying HDL module implements the front-end logic interface and FLES link protocol in the front-end FPGAs. Prototypes of all Input Interface components have been implemented and integrated into the FLES framework. In contrast to earlier prototypes, which included components to work without a FPGA layer between FLES and FEE, the structure matches the foreseen final setup. This allows the implementation and evaluation of the final CBM read-out chain. An overview of the FLES Input Interface as well as studies on system integration and system start-up are presented.

Stratigraphy of the Charqueadas Carboniferous basin, Santa Rita, RS, Brazil

Energy Technology Data Exchange (ETDEWEB)

Mendes Piccoli, A.E.; Holz, M.; Munaro, P.

1985-01-01

Sedimentological analyses of about 80 drill cores from the Charqueadas - Santa Rita Coal Field, west of Porto Alegre, Rio Grande do Sul State, were made. The Itarare Group is characterized by pelites of lacustrine origin and conglomerates and sandstones of alluvial fans, mainly in the north western region. A shallow lacustrine and paludal system characterize the Rio Bonito Formation, comprising coal seams and associated pelitic sediments, as well as some paraconglomerates and sandstone layers. The contact between these units is established by the colour of the pelites, differences in sedimentary textures, structures and palynological data. A marine transgression caused the sediments of the Rio Bonito Formation to be covered by coastal sandstones and pelites of the Palermo Formation, of tidal flat origin. Today, the coal layers and sediments have been eroded southward and slope gently to the north of the area.

MAPEAMENTO GEOMORFOLÓGICO DA ÁREA ABRANGIDA PELA CARTA TOPOGRÁFICA DE SANTA MARIA – RS COMO SUBSÍDIO AO PLANEJAMENTO AMBIENTAL

Directory of Open Access Journals (Sweden)

Marilene Dias do Nascimento

2010-09-01

Full Text Available A pesquisa geomorfológica tem como propósito reconhecer e interpretar os fenômenos que tenham como expressão as formas do relevo da terra. Nesse sentido, o presente trabalho de pesquisa teve como finalidade o mapeamento e a análise geomorfológica da área abrangida pela Carta Topográfica de Santa Maria – RS, baseado na metodologia dos estudos geomorfológicos, desenvolvidos no Leste Europeu. Esses são fundamentados nas idéias de Walter Penk, nos conceitos de Morfoestrutura e Morfoescultura de Gerasimov e Mescherikov (1968 e no tratamento técnico da Taxonomia de Relevo desenvolvido por Ross (1992, para fins de planejamento ambiental. Como material de apoio utilizou-se Cartas Topográficas de Santa Maria em escalas 1:250.000 e 1:50.000, mapas geomorfológicos, geológicos, climáticos, hidrográficos e de solos do RS, imagens de satélite e os Softwares Spring e Corel Draw. A unidade morfoestrutural identificada é a Bacia Sedimentar do Paraná que corresponde ao 1º táxon. Inseridas nessa unidade foram individualizadas três unidades morfoesculturais distintas, correspondentes ao 2º táxon. Ao norte a Porção Sul dos Planaltos e Chapadas da Bacia do Paraná, ao sul, a Depressão Periférica Sul-Rio-grandense e entre essas duas o Rebordo do Planalto da Bacia do Paraná. Na Porção Sul dos Planaltos e Chapadas da Bacia do Paraná predominam as formas denudacionais (3º táxon de superfícies planas (Dp, com topos convexos (Dc e com topos tabulares (Dt (4º táxon e vertentes convexas (5º táxon. Na Depressão Periférica Sul-rio-grandense predominam as formas agradacionais de planície fluvial (Apf e as formas denudacionais de topos convexos (Dc e de superfícies planas (Dp e vertentes côncavas a convexas. No Rebordo do Planalto da Bacia do Paraná, predominam as formas denudacionais, com topos convexos (Dc, com topos aguçados (Da e em formas de Escarpas (De, com padrão de dissecação muito elevados e vertentes retilíneas a

Responses of cerebral GABA-containing CBM neuron to taste stimulation with seaweed extracts in Aplysia kurodai.

Science.gov (United States)

Narusuye, Kenji; Kinugawa, Aiko; Nagahama, Tatsumi

2005-11-01

Aplysia kurodai distributed along Japan feeds well on Ulva pertusa but rejects Gelidium amansii with distinctive patterned movements of the jaws and radula. On the ventral side of the cerebral M cluster, four cell bodies of higher order neurons that send axons to the buccal ganglia are distributed (CBM neurons). We have previously shown that the dopaminergic CBM1 modulates basic feeding circuits in the buccal ganglia for rejection by firing at higher frequency after application of the aversive taste of seaweed such as Gelidium amansii. In the present experiments immunohistochemical techniques showed that the CBM3 exhibited gamma-aminobutyric acid (GABA)-like immunoreactivity. The CBM3 may be equivalent to the CBI-3 involved in changing the motor programs from rejection to ingestion in Aplysia californica. The responses of the CBM3 to taste stimulation of the lips with seaweed extracts were investigated by the use of calcium imaging. The calcium-sensitive dye, Calcium Green-1, was iontophoretically introduced into a cell body of the CBM3 using a microelectrode. Application of Ulva pertusa or Gelidium amansii extract induced different changes in fluorescence in the CBM3 cell body, indicating that taste of Ulva pertusa initially induced longer-lasting continuous spike responses at slightly higher frequency compared with that of Gelidium amansii. Considering a role of the CBM3 in the pattern selection, these results suggest that elongation of the initial firing response may be a major factor for the CBM3 to switch the buccal motor programs from rejection to ingestion after application of different tastes of seaweeds in Aplysia kurodai. (c) 2005 Wiley Periodicals, Inc.

The Development of a Gas–Liquid Two-Phase Flow Sensor Applicable to CBM Wellbore Annulus

Directory of Open Access Journals (Sweden)

Chuan Wu

2016-11-01

Full Text Available The measurement of wellbore annulus gas–liquid two-phase flow in CBM (coalbed methane wells is of great significance for reasonably developing gas drainage and extraction processes, estimating CBM output, judging the operating conditions of CBM wells and analyzing stratum conditions. Hence, a specially designed sensor is urgently needed for real-time measurement of gas–liquid two-phase flow in CBM wellbore annulus. Existing flow sensors fail to meet the requirements of the operating conditions of CBM wellbore annulus due to such factors as an inapplicable measurement principle, larger size, poor sealability, high installation accuracy, and higher requirements for fluid media. Therefore, based on the principle of a target flowmeter, this paper designs a new two-phase flow sensor that can identify and automatically calibrate different flow patterns of two-phase flows. Upon the successful development of the new flow sensor, lab and field tests were carried out, and the results show that the newly designed sensor, with a measurement accuracy of ±2.5%, can adapt to the operating conditions of CBM wells and is reliable for long-term work.

O Comportamento da Receita Pública Municipal: Um Estudo de Caso no Município de Santa Maria (RS

Directory of Open Access Journals (Sweden)

Cristiano Sausen Soares

2014-01-01

Full Text Available The study aimed to identify the behavior of government revenue in the municipality of Santa Maria (RS, comparing revenue with own revenues and transfers relating the possible actions that the government can justify such behavior. To understand the behavior of the public revenue of the mu - nicipality, there was a qualitative study which analyzed secondary data from the period 2004-2011. Additionally, unstructured interviews were conducted with experts such as superintendents, managers and tax collection. The results showed an increase in revenues of the municipality, especially from the year 2008. As for the recipes themselves, it was found that the largest increase occurred with the ISS (Service Tax of any kind, reaching 90.5% during the period. On the revenue transferred by the union and states, there is a greater share of the ICMS (Tax on Goods and Services, with an increase of 50.58%. It is worth noting the significant increase of Fundeb (Fund for the Maintenance and Development of Basic Education and Enhancement of Professional Education with 118.47% over the period. According to respondents, from 2008, there was an increase in school enrollment in the city, leading to greater participation in the Fund. In general, it was noted that, over the years, the public revenue of the municipality has increased, this behavior being attributed to government actions aimed at his elevation. Due to the limitations of this research, it is suggested to carry out further comparative studies with other municipalities.

Cerebral CBM1 neuron contributes to synaptic modulation appearing during rejection of seaweed in Aplysia kurodai.

Science.gov (United States)

Narusuye, Kenji; Nagahama, Tatsumi

2002-11-01

The Japanese species Aplysia kurodai feeds well on Ulva but rejects Gelidium with distinctive rhythmic patterned movements of the jaws and radula. We have previously shown that the patterned jaw movements during the rejection of Gelidium might be caused by long-lasting suppression of the monosynaptic transmission from the multiaction MA neurons to the jaw-closing (JC) motor neurons in the buccal ganglia and that the modulation might be directly produced by some cerebral neurons. In the present paper, we have identified a pair of catecholaminergic neurons (CBM1) in bilateral cerebral M clusters. The CBM1, probably equivalent to CBI-1 in A. californica, simultaneously produced monosynaptic excitatory postsynaptic potentials (EPSPs) in the MA and JC neurons. Firing of the CBM1 reduced the size of the inhibitory postsynaptic currents (IPSCs) in the JC neuron, evoked by the MA spikes, for >100 s. Moreover, the application of dopamine mimicked the CBM1 modulatory effects and pretreatment with a D1 antagonist, SCH23390, blocked the modulatory effects induced by dopamine. It could also largely block the modulatory effects induced by the CBM1 firing. These results suggest that the CBM1 may directly modulate the synaptic transmission by releasing dopamine. Moreover, we explored the CBM1 spike activity induced by taste stimulation of the animal lips with seaweed extracts by the use of calcium imaging. The calcium-sensitive dye, Calcium Green-1, was iontophoretically loaded into a cell body of the CBM1 using a microelectrode. Application of either Ulva or Gelidium extract to the lips increased the fluorescence intensity, but the Gelidium extract always induced a larger change in fluorescence compared with the Ulva extract, although the solution used induced the maximum spike responses of the CBM1 for each of the seaweed extracts. When the firing frequency of the CBM1 activity after taste stimulation was estimated, the Gelidium extract induced a spike activity of ~30 spikes

ANÁLISE DENDROECOLÓGICA DE Ocotea pulchella Nees et Mart. ex Nees (CANELA LAGEANA NA SERRA GERAL DE SANTA MARIA, RS, BRASIL

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Peter Spathelf

2000-06-01

Full Text Available Foram estudadas as relações entre variáveis climáticas e o incremento em diâmetro do tronco de cinco árvores de Ocotea pulchella localizadas às margens de uma barragem no município de Itaára, RS. Os dados de crescimento, em diâmetro, foram obtidos mediante análise de tronco, utilizando-se seções transversais retiradas na altura de 1,3 m (DAP, sendo os incrementos radiais determinados por meio da média de quatro raios, diametralmente, opostos. As seqüências médias dos incrementos foram estandartizadas para salientar a variação a curto prazo. Os dados climáticos são oriundos da estação meteorológica do município de Santa Maria, RS. Foram calculadas grandezas climáticas compostas, como a evapotranspiração e o balanço hídrico, para melhor descrever as condições hídricas de crescimento das árvores. Foram determinados anéis de crescimento característicos e sensitividades das seqüências de crescimento. Possíveis mudanças no estado de competição das árvores e seu efeito no crescimento foram estudados. Além disso, foram relacionados o incremento radial e as variáveis climáticas selecionadas por intermédio de análise de correlação. Não foi possível identificar nenhuma variável climática que, coerentemente, tenha influenciado no incremento durante o período observado. Os resultados mostram que o excesso de água influencia no crescimento diamétrico das árvores.

Padrões motores de escolares de oito a nove anos de idade da cidade de Santa Rosa, RS

OpenAIRE

Loi, Luiz Serafim de Mello

1999-01-01

Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Desportos. O desenvolvimento motor é um assunto que necessita maiores estudos, haja vista a importância cada vez maior do desenvolvimento pleno da criança, desde os primeiros anos de vida. Este estudo utilizando como Marco Referencial Teórico (MRT) o modelo de desenvolvimento motor de Gallahue & Ozmun (1998) teve por objetivo verificar o perfil motor de escolares de oito e nove anos de idade, da cidade de Santa Rosa...

Goals and status of the CBM experiment

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Senger P.

2010-10-01

Full Text Available The goal of the heavy-ion collision program at the future Facility for Antiproton and Ion Research (FAIR in Darmstadt (Germany is to explore the phase diagram of strongly interacting matter in the region of the highest baryon densities. The CBM research program addresses fundamental aspects of QCD such as the equation-of-state of highly compressed baryonic matter, the deconfinement phase transition and its critical endpoint, chiral symmetry restoration at high baryon densities, and the in-medium properties of hadrons. The corresponding key observables comprise low-mass vector mesons decaying into lepton pairs which serve as penetrating probes, hidden and open charm produced at threshold beam energies, (multi- strange particles, and global features like collective flow and event-by-event fluctuations. The experimental task is to identify both hadrons and leptons and to detect rare probes in a heavy-ion environment. The experimental challenge is to select rare events in nucleus-nucleus collisions with charged particle multiplicities of about 1000 per central event at reaction rates of up to 10 MHz. Such measurements require fast and radiation hard detectors, fast and selftriggered read-out electronics, a high-speed data acquisition system, and online event selection based on full track reconstruction. The layout of the CBM detector system and the results of feasibility studies will be presented. More than 400 scientists from 50 institutions and 15 countries actually participate in the realization of the CBM experiment which represents a major international effort in future heavy-ion physics.

What does the CBM-maze test measure?

NARCIS (Netherlands)

Muijselaar, M.M.L.; Kendeou, P.; de Jong, P.F.; van den Broek, P.W.

2017-01-01

In this study, we identified the code-related (decoding, fluency) and language comprehension (vocabulary, listening comprehension) demands of the CBM-Maze test, a formative assessment, and compared them to those of the Gates–MacGinitie test, a standardized summative assessment. The demands of these

CBM Resources/reserves classification and evaluation based on PRMS rules

Science.gov (United States)

Fa, Guifang; Yuan, Ruie; Wang, Zuoqian; Lan, Jun; Zhao, Jian; Xia, Mingjun; Cai, Dechao; Yi, Yanjing

2018-02-01

This paper introduces a set of definitions and classification requirements for coalbed methane (CBM) resources/reserves, based on Petroleum Resources Management System (PRMS). The basic CBM classification criterions of 1P, 2P, 3P and contingent resources are put forward from the following aspects: ownership, project maturity, drilling requirements, testing requirements, economic requirements, infrastructure and market, timing of production and development, and so on. The volumetric method is used to evaluate the OGIP, with focuses on analyses of key parameters and principles of the parameter selection, such as net thickness, ash and water content, coal rank and composition, coal density, cleat volume and saturation and absorbed gas content etc. A dynamic method is used to assess the reserves and recovery efficiency. Since the differences in rock and fluid properties, displacement mechanism, completion and operating practices and wellbore type resulted in different production curve characteristics, the factors affecting production behavior, the dewatering period, pressure build-up and interference effects were analyzed. The conclusion and results that the paper achieved can be used as important references for reasonable assessment of CBM resources/reserves.

Measurements of the mirror surface homogeneity in the CBM-RICH

Energy Technology Data Exchange (ETDEWEB)

Lebedeva, Elena; Hoehne, Claudia [II. Physikalisches Institut, JLU Giessen (Germany); Collaboration: CBM-Collaboration

2016-07-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR (Facility for Antiproton and Ion Research) complex will investigate the phase diagram of strongly interacting matter at high baryon densities and moderate temperatures in A+A collisions from 2-11 AGeV (SIS100) beam energy. One of the key detector components required for the CBM physics program is the RICH (Ring Imaging CHerenkov) detector, which is developed for efficient and clean electron identification and pion suppression. The CBM-RICH detector is being planned with gaseous radiator and in a standard projective geometry with focusing mirror elements and photon detector planes. One of the important criteria for the selection of appropriate mirrors is their optical surface quality (surface homogeneity). It defines the imaging quality of projected Cherenkov rings, and directly effects the ring finding and fitting performance. The global homogeneity has been tested with the D0 measurement. Local deformations e.g. by the mirror holding structure can be investigated with the Ronchi test and Shack-Hartmann method from which first results are discussed in this contribution.

Qualidade higiênico-sanitária dos restaurantes cadastrados na Vigilância Sanitária de Santa Maria, RS, Brasil, no período de 2006 a 2010 Hygienic-sanitary status of restaurants recorded in the health surveillance unit of Santa Maria, Rio Grande do Sul, Brazil, from 2006 to 2010

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Laissa Medeiros

2013-01-01

Full Text Available O presente estudo teve por objetivo avaliar, através dos roteiros de inspeção, as condições higiênico-sanitárias dos restaurantes cadastrados pela Vigilância Sanitária (VISA do município de Santa Maria - RS. Neste estudo, foram incluídos 315 roteiros de vistorias provenientes de 120 restaurantes com alvarás sanitários e fiscalizados no período de janeiro de 2006 a dezembro de 2010. As variáveis (a condições de armazenamento dos alimentos, (b equipamentos de conservação a frio e a quente, (c estrutura física do estabelecimento e (d condições higiênico-sanitária dos manipuladores dos alimentos foram compiladas e avaliadas. Os resultados foram analisados estatisticamente pelo programa SAS (Statistical Analysis System versão 9.2 e submetidos aos testes de Qui-quadrado e Fischer. Constatou-se que, no ano de 2009, ocorreram os maiores índices de desconformidades legais nos aspectos higênico-sanitários nos estabelecimentos pesquisados. Esse fato pode estar relacionado ao aumento do número de fiscais sanitários contratados, à descentralização do setor de fiscalização, o que possibilitou a realização de um maior detalhamento dos requisitos fundamentais a serem avaliados nos roteiros de vistoria e, consequentemente, havendo um aumento nas notificações oficiais. Além disso, no ano de 2010, os estabelecimentos apresentaram melhores índices de adequação às boas práticas de produção de alimentos. Com base nas informações obtidas, verificou-se que os serviços prestados pelo setor de alimentos da VISA de Santa Maria estão em crescente evolução.The present study was to evaluate, through the forms of inspection, the sanitary conditions of restaurants registered for Sanitary Surveillance (VISA in the municipality of Santa Maria, RS, Brazil. This study included 315 inspection forms, from 120 restaurants with sanitary permits from January 2006 to December 2010. The following variables: (a food storage conditions

A solution for the inner area of CBM-TOF with pad-MRPC

Energy Technology Data Exchange (ETDEWEB)

Wang, Y. [Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Huang, X.J., E-mail: huangxj12@mails.tsinghua.edu.cn [Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Lyu, P.F.; Han, D.; Xie, B.; Li, Y.J. [Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Herrmann, N.; Deppner, I.; Loizeau, P.; Simon, C. [Physikalisches Institute, University Heidelberg, Heidelberg (Germany); Frühauf, J.; Kiš, M. [GSI Helmholtzzentrum fr Schwerionenforschung, GSI, Damstadt (Germany)

2017-02-11

The Compressed Baryonic Matter (CBM) experiment has decided to use the Multi-gap Resistive Plate Chambers(MRPC) technology to build its Time-Of-Flight (TOF) wall. CBM-TOF requires a rate capability over 20 kHz/cm{sup 2} for inner region. A 10-gap pad-MRPC assembled with low resistive glass is designed to construct this area. The prototypes, which consist of 10×0.22 mm gas gaps and 2×8 20 mm×20 mm readout pads, require fewer electronic channels compared to the strip design. A timing resolution of around 60 ps and an efficiency above 98% were obtained in a cosmic test and a beam test taken in 2014 October GSI beam time. The results show that the real-size prototypes fulfill the requirements of the CBM-TOF.

Control software for the CBM readout chain

Energy Technology Data Exchange (ETDEWEB)

Loizeau, Pierre-Alain [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH (Germany)

2016-07-01

The Compressed Baryonic Matter (CBM) experiment, which will be built at FAIR, will use free-streaming readout electronics to acquire high-statistics data-sets of physics probes in fixed target heavy-ion collisions. Since no simple signatures suitable for a hardware trigger are available for most of them, reconstruction and selection of the interesting collisions will be done in software, in a computer farm called First Level Event Selector (FLES). The raw data coming from the detectors is pre-processed, pre-calibrated and aggregated in a FPGA based layer called Data Preprocessing Boards (DPB). IPbus will be used to communicate with the DPBs and through them with the elements of the readout chain closer to detectors. A slow control environment based on this software is developed by CBM to configure in an efficient way the DPBs as well as the Front-End Electronics and monitor their performances. This contribution presents the layout planned for the slow control software, its first implementation and corresponding test results.

O aterro da caturrita em Santa Maria – RS: uma atualização quanto aos potenciais da digestão anaeróbia

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Tiago Luis Gomes

2009-01-01

Full Text Available As oportunidades do processo de digestão anaeróbia, em aterros sanitários e controlados, são ligadas à formação de biogásatravés da biodegradação da matéria orgânica em ambiente predominantemente anaeróbio. Com isso, através de um ajuste decapacidade do aterro da Caturrita em Santa Maria-RS, que consiste no produto entre a massa de resíduos (467.929 toneladas quecomporta a célula e o fator de recuperação do gás metano (RF=0,7, sendo o mesmo relacionado, principalmente ao percentual deresíduos domésticos que chegam ao aterro (alto teor de matéria orgânica de fácil degradação, obteve-se um aproveitamento potencialde 327.550 toneladas de resíduos depositados, resultando num aterro com baixa capacidade de produção de biogás. A recuperaçãototal do metano entre 2013 e 2033, considerando um rendimento na captação de gases de 70%, resultou 17.529.657m3, através dautilização do método Scholl Canyon. O total da receita estimada para o mesmo período, admitindo uma comercialização conservadora(aterro Bandeirantes em São Paulo que é de € 19,20 de créditos de carbono em € 10,00 por tonelada equivalente de CO2 (eCO2, eenergia elétrica em um valor de € 0,0326/kWh que é referência para o projeto NovaGerar no Rio de Janeiro, seria de € 3.604.650, ouem torno de R$ 11.030.229, isto é, um faturamento mensal de R$ 45.960,00.Abstract The anaerobic digestion process opportunities,about sanitary and controlled landfills, are related to a biogasformation process through the biodegradation of organicsubstances in a predominantly anaerobic environment. Thus,through capacity adjustment of the Caturrita’s landfill in SantaMaria-RS reached an exploitation potential of 327,550 tons ofdeposited residues, resulting in a landfill, which has a lowbiogas production capacity. The methane recovered between2013 and 2033, considering an availability of 70%, came to be17,529,657m3. Admitting the carbon credits and electricenergy

Crystallization and preliminary diffraction studies of CBM3b of cellobiohydrolase 9A from Clostridium thermocellum

Energy Technology Data Exchange (ETDEWEB)

Jindou, Sadanari [Department of Molecular Microbiology and Biotechnology, Tel Aviv University 69978 (Israel); Petkun, Svetlana [Department of Molecular Microbiology and Biotechnology, Tel Aviv University 69978 (Israel); The Daniella Rich Institute for Structural Biology, Tel Aviv University 69978 (Israel); Shimon, Linda [Department of Chemical Research Support, The Weizmann Institute of Science, Rehovot 76100 (Israel); Bayer, Edward A. [Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot 76100 (Israel); Lamed, Raphael; Frolow, Felix, E-mail: mbfrolow@post.tau.ac.il [Department of Molecular Microbiology and Biotechnology, Tel Aviv University 69978 (Israel); The Daniella Rich Institute for Structural Biology, Tel Aviv University 69978 (Israel)

2007-12-01

The cloning, expression, purification and crystallization of the CBM3b module of cellobiohydrolase 9A from C. thermocellum is described. The crystals diffract to 2.68 Å. Family 3 carbohydrate-binding modules (CBM3s) are associated with the scaffoldin subunit of the multi-enzyme cellulosome complex and with the family 9 glycoside hydrolases, which are multimodular enzymes that act on plant cell-wall polysaccharides, notably cellulose. Here, the crystallization of CBM3b from cellobiohydrolase 9A is reported. The crystals are tetragonal and belong to space group P4{sub 1} or P4{sub 3}. X-ray diffraction data for CBM3b have been collected to 2.68 Å resolution on beamline ID14-4 at the ESRF.

ATIVIDADES RECREATIVAS E LÚDICAS: um estudo nas escolas estaduais da cidade de Santa Vitória do Palmar, RS – Brasil

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Alex Borges Dias

2017-11-01

Full Text Available Os processos educativos são fundamentais para a formação de cidadãos mais conscientes de seu papel na construção de uma sociedade mais justa e igualitária. Em um mundo onde as atividades humanas são constantemente aceleradas pelas práticas capitalistas, se torna cada vez mais necessário pensar o papel da educação na formação de novos cidadãos conscientes de sua importância na sociedade. Desse modo, este trabalho teve por objetivo identificar as atividades recreativas e lúdicas que contribuem nos processos educativos dos alunos do 1º ano das escolas estaduais em Santa Vitória do Palmar, RS - Brasil. Na metodologia foi feita uma pesquisa bibliográfica. Para a coleta de dados foram feitas entrevistas com os professores responsáveis pelas turmas do primeiro ano de cada escola e foi utilizado o método de observação não-participante, além do levantamento fotográfico. Identificou-se que todas as escolas estaduais da cidade possuem atividades recreativas e lúdicas que contribuem para os processos educativos dos alunos matriculados.

Conceptual considerations for CBM databases

Energy Technology Data Exchange (ETDEWEB)

Akishina, E. P.; Aleksandrov, E. I.; Aleksandrov, I. N.; Filozova, I. A.; Ivanov, V. V.; Zrelov, P. V. [Lab. of Information Technologies, JINR, Dubna (Russian Federation); Friese, V.; Mueller, W. [GSI, Darmstadt (Germany)

2014-07-01

We consider a concept of databases for the Cm experiment. For this purpose, an analysis of the databases for large experiments at the LHC at CERN has been performed. Special features of various DBMS utilized in physical experiments, including relational and object-oriented DBMS as the most applicable ones for the tasks of these experiments, were analyzed. A set of databases for the CBM experiment, DBMS for their developments as well as use cases for the considered databases are suggested.

Conceptual considerations for CBM databases

International Nuclear Information System (INIS)

Akishina, E.P.; Aleksandrov, E.I.; Aleksandrov, I.N.; Filozova, I.A.; Ivanov, V.V.; Zrelov, P.V.; Friese, V.; Mueller, W.

2014-01-01

We consider a concept of databases for the Cm experiment. For this purpose, an analysis of the databases for large experiments at the LHC at CERN has been performed. Special features of various DBMS utilized in physical experiments, including relational and object-oriented DBMS as the most applicable ones for the tasks of these experiments, were analyzed. A set of databases for the CBM experiment, DBMS for their developments as well as use cases for the considered databases are suggested.

Event reconstruction in the RICH detector of the CBM experiment at FAIR

International Nuclear Information System (INIS)

Adamczewski, J.; Becker, K.-H.; Belogurov, S.; Boldyreva, N.; Chernogorov, A.; Deveaux, C.; Dobyrn, V.; Dürr, M.; Eom, J.; Eschke, J.; Höhne, C.; Kampert, K.-H.; Kleipa, V.; Kochenda, L.; Kolb, B.; Kopfer, J.; Kravtsov, P.; Lebedev, S.; Lebedeva, E.; Leonova, E.

2014-01-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR facility will investigate the QCD phase diagram at high net-baryon densities and moderate temperatures. One of the key signatures will be di-leptons emitted from the hot and dense phase in heavy-ion collisions. Measuring di-electrons, a high purity of identified electrons is required in order to suppress the background. Electron identification in CBM will be performed by a Ring Imaging Cherenkov (RICH) detector and Transition Radiation Detectors (TRD). In order to access the foreseen rare probes, the detector and the data acquisition have to handle interaction rates up to 10 MHz. Therefore, the development of fast and efficient event reconstruction algorithms is an important and challenging task in CBM. In this contribution event reconstruction and electron identification algorithms in the RICH detector are presented. So far they have been developed on simulated data but could already be tested on real data from a RICH prototype testbeam experiment at the CERN-PS. Efficient and fast ring recognition algorithms in the CBM-RICH are based on the Hough Transform method. Due to optical distortions of the rings, an ellipse fitting algorithm was elaborated to improve the ring radius resolution. An efficient algorithm based on the Artificial Neural Network was implemented for electron identification in RICH. All algorithms were significantly optimized to achieve maximum speed and minimum memory consumption. - Highlights: • Ring Imaging Cherenkov detector will serve for electron identification in CBM. • We present efficient ring recognition algorithm based on the Hough Transform method. • Developed algorithms were significantly optimized to achieve maximum speed up. • Electron identification algorithm in RICH based on the Artificial Neural Network. • Developed algorithms were successfully tested on real data from the RICH prototype

Event reconstruction in the RICH detector of the CBM experiment at FAIR

Energy Technology Data Exchange (ETDEWEB)

Adamczewski, J. [GSI Darmstadt (Germany); Becker, K.-H. [University Wuppertal (Germany); Belogurov, S. [ITEP Moscow (Russian Federation); Boldyreva, N. [PNPI Gatchina (Russian Federation); Chernogorov, A. [ITEP Moscow (Russian Federation); Deveaux, C. [University Gießen (Germany); Dobyrn, V. [PNPI Gatchina (Russian Federation); Dürr, M. [University Gießen (Germany); Eom, J. [Pusan National University (Korea, Republic of); Eschke, J. [GSI Darmstadt (Germany); Höhne, C. [University Gießen (Germany); Kampert, K.-H. [University Wuppertal (Germany); Kleipa, V. [GSI Darmstadt (Germany); Kochenda, L. [PNPI Gatchina (Russian Federation); Kolb, B. [GSI Darmstadt (Germany); Kopfer, J. [University Wuppertal (Germany); Kravtsov, P. [PNPI Gatchina (Russian Federation); Lebedev, S., E-mail: s.lebedev@gsi.de [University Gießen (Germany); Lebedeva, E. [University Gießen (Germany); Leonova, E. [PNPI Gatchina (Russian Federation); and others

2014-12-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR facility will investigate the QCD phase diagram at high net-baryon densities and moderate temperatures. One of the key signatures will be di-leptons emitted from the hot and dense phase in heavy-ion collisions. Measuring di-electrons, a high purity of identified electrons is required in order to suppress the background. Electron identification in CBM will be performed by a Ring Imaging Cherenkov (RICH) detector and Transition Radiation Detectors (TRD). In order to access the foreseen rare probes, the detector and the data acquisition have to handle interaction rates up to 10 MHz. Therefore, the development of fast and efficient event reconstruction algorithms is an important and challenging task in CBM. In this contribution event reconstruction and electron identification algorithms in the RICH detector are presented. So far they have been developed on simulated data but could already be tested on real data from a RICH prototype testbeam experiment at the CERN-PS. Efficient and fast ring recognition algorithms in the CBM-RICH are based on the Hough Transform method. Due to optical distortions of the rings, an ellipse fitting algorithm was elaborated to improve the ring radius resolution. An efficient algorithm based on the Artificial Neural Network was implemented for electron identification in RICH. All algorithms were significantly optimized to achieve maximum speed and minimum memory consumption. - Highlights: • Ring Imaging Cherenkov detector will serve for electron identification in CBM. • We present efficient ring recognition algorithm based on the Hough Transform method. • Developed algorithms were significantly optimized to achieve maximum speed up. • Electron identification algorithm in RICH based on the Artificial Neural Network. • Developed algorithms were successfully tested on real data from the RICH prototype.

Development of an alignment system for the CBM rich

Energy Technology Data Exchange (ETDEWEB)

Hoehne, Claudia; Mahmoud, Tariq; Bendarouach, Jordan [Justus Liebig University, Giessen (Germany); Collaboration: CBM-Collaboration

2015-07-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR complex will investigate the phase diagram of strongly interacting matter at high baryon density and moderate temperatures in A+A collisions from 4-35 AGeV. One of the key detector components required for the CBM physics program is the RICH detector, which is developed for efficient and clean electron identification and pion suppression. Main detector components are a CO{sub 2} gaseous radiator, MAPMT or MCP photo-detectors and spherical glass mirror tiles, used as focusing elements, with spectral reflectivity down to the UV range. An important aspect to guarantee a stable operation of the RICH detector is the alignment and continuous monitor of the mirrors. CLAM (Continuous Line Alignment Monitoring), an alignment procedure developed by the COMPASS experiment, is planned to be used also for the RICH mirror system. A smaller-scale version has been implemented in the CBM RICH prototype detector and tested at the Cern PS/T9 beamline in November 2014. Using a grid and target dots made of retro-reflective material, it is possible to align the mirrors and monitor their displacements over time by analyzing and applying mathematical calculations on photographic images of the grid and targets reflected on the mirrors. The concept, first data and results of image processing are presented and discussed.

The obesity-associated polymorphisms FTO rs9939609 and MC4R rs17782313 and endometrial cancer risk in non-Hispanic white women.

Directory of Open Access Journals (Sweden)

Galina Lurie

2011-02-01

Full Text Available Overweight and obesity are strongly associated with endometrial cancer. Several independent genome-wide association studies recently identified two common polymorphisms, FTO rs9939609 and MC4R rs17782313, that are linked to increased body weight and obesity. We examined the association of FTO rs9939609 and MC4R rs17782313 with endometrial cancer risk in a pooled analysis of nine case-control studies within the Epidemiology of Endometrial Cancer Consortium (E2C2. This analysis included 3601 non-Hispanic white women with histologically-confirmed endometrial carcinoma and 5275 frequency-matched controls. Unconditional logistic regression models were used to assess the relation of FTO rs9939609 and MC4R rs17782313 genotypes to the risk of endometrial cancer. Among control women, both the FTO rs9939609 A and MC4R rs17782313 C alleles were associated with a 16% increased risk of being overweight (p = 0.001 and p = 0.004, respectively. In case-control analyses, carriers of the FTO rs9939609 AA genotype were at increased risk of endometrial carcinoma compared to women with the TT genotype [odds ratio (OR  = 1.17; 95% confidence interval (CI: 1.03-1.32, p = 0.01]. However, this association was no longer apparent after adjusting for body mass index (BMI, suggesting mediation of the gene-disease effect through body weight. The MC4R rs17782313 polymorphism was not related to endometrial cancer risk (per allele OR = 0.98; 95% CI: 0.91-1.06; p = 0.68. FTO rs9939609 is a susceptibility marker for white non-Hispanic women at higher risk of endometrial cancer. Although FTO rs9939609 alone might have limited clinical or public health significance for identifying women at high risk for endometrial cancer beyond that of excess body weight, further investigation of obesity-related genetic markers might help to identify the pathways that influence endometrial carcinogenesis.

Maturação fisiológica e coleta de sementes de Eugenia uniflora L. (Pitanga, Santa Maria, RS.

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Angela Luciana de Avila

2009-09-01

Full Text Available Normal 0 21 MicrosoftInternetExplorer4 Este estudo teve como objetivo acompanhar a maturação fisiológica, seus parâmetros indicadores e identificar o momento adequado para a coleta de sementes de Eugenia uniflora, avaliando também a incidência de fungos em frutos e sementes. A pesquisa foi realizada de agosto a outubro de 2004 em Santa Maria, RS. A coleta dos frutos e sementes ocorreu semanalmente, partindo de três árvores matrizes, com início aos 7 dias após a antese (DAA e término aos 77 DAA. As variáveis observadas foram: altura, diâmetro, peso verde e sanidade de frutos e sementes e teor de umidade, massa seca e germinação das sementes. Identificou-se que a época adequada para a coleta das sementes, no período e local de estudo, ocorreu entre 56 e 63 DAA, quando os frutos apresentavam coloração vermelha e as sementes elevada germinação. Nesse período, o tamanho e o peso de frutos e sementes atingiram seus valores máximos e o teor de umidade e matéria seca das sementes mostraram tendência à estabilização. Os gêneros fúngicos Cladosporium sp. e Alternaria sp.  apresentaram as maiores taxas de incidência nos frutos e nas sementes e podem influenciar o armazenamento e a germinação das sementes de mudas de Eugenia uniflora.

Vascular endothelial growth factor (VEGF-related single nucleotide polymorphisms rs10738760 and rs6921438 are not associated with diabetic retinopathy (DR in Slovenian patients with type 2 diabetes mellitus (T2DM

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Rifet Terzić

2017-11-01

Full Text Available Diabetic retinopathy (DR is a complication of diabetes characterized by vascular permeability, increased tissue ischemia, and angiogenesis. One of the most important proteins involved in angiogenesis is vascular endothelial growth factor (VEGF, also known as VEGFA. A previous study demonstrated that two single nucleotide polymorphisms (SNPs, rs6921438 and rs10738760, account for nearly half the variation in circulating VEGF levels. The aim of our study was to assess the association between rs6921438 and rs10738760 and DR in Slovenian patients with type 2 diabetes mellitus (T2DM. This case-control study enrolled 1037 unrelated Slovenian individuals (Caucasians with T2DM. DR group included 415 T2DM patients with DR, while control group included 622 T2DM patients with no clinical signs of DR. The clinical and laboratory data were obtained from the medical records of the patients. The genotyping of rs6921438 and rs10738760 SNPs was carried out with real-time PCR assays. Significant differences were observed between patients with DR and controls in the duration of diabetes (p < 0.001, insulin therapy (p < 0.001, glycated hemoglobin (p = 0.001, body mass index (p = 0.002, total cholesterol (p = 0.002, and low-density lipoprotein cholesterol (p < 0.001. However, we did not observe significant differences in the genotype and allele distribution of the two SNPs, between DR and control group (p < 0.05. Logistic regression analysis showed that rs6921438 and rs10738760 were not independent genetic risk factors for DR in the co-dominant model adjusted for the above-mentioned clinical and laboratory data. In conclusion, VEGF-related SNPs rs10738760 and rs6921438 are not associated with DR in our group of Slovenian patients (Caucasians with T2DM.

PHYSICAL ACTIVITY PRACTICE AND THE SOCIO-ECONOMIC CONDITIONS: comparative study of children and adolescents of the municipality of Santa Cruz do Sul – RS

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Matheus Cezar Maria

2012-11-01

Full Text Available The aim of this study was to verify possible differences in the levels of physical activity related to the socio-economic conditions of schoolchildren in the municipality of Santa Cruz do Sul-RS. It is of transversal-descriptive character, and its subjects are 350 schoolchildren, aged 7 to 17, of both genders. For data collection a previously validated and adapted questionnaire was used, while the chi-quadrat-test was used for statistical analysis. Significant statistical differences were detected in the manner of locomotion, with regard to the school level and socio-economic status, for both genders. The results showed that students from urban areas and of inferior socio-economic levels showed more active in this respect. In the practice of physical activities, the results pointed to a reverse relation of this variable with the socio-economic level. At school level, a prevalence of inactive subjects from the rural area was observed. The difference in the form of locomotion and the physical activities of the evaluated schoolchildren, both at school level and at their socio-economic level, demonstrates different profiles of schoolchildren, which should be considered in future intervention programs.

Methodology for the exploration of coal bed methane (CBM in Colombia coal basins

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Jorge E. Mariño

2013-07-01

additional equipment have been adapted and improved in the UPTC by Geological Engineering research group during the last years. These CBM guides have been written following the current knowledge on CBM and propose additional recommendations for making the sampling and gas measuring more reliable and supportive of the CBM exploration projects that are taking place in the different coal basins in Colombia.

The petrographic district of Santa Teresa 1st. communication

International Nuclear Information System (INIS)

Giglio, M.; Oyhantcabal, P.

1984-01-01

Abstract.it was possible to found the existence of a potas sic rocks petrographic province as a first stage of the geological, petrographic and geochemical study of the Sta. Teresa granitic complex of cambric age.The Or/Ab/An ratio of most of this rocks lies on the orthoclase field of the 'Diagram of Higazy', while the K2/Na20tCaO ratio is bigger than 1 .This da tta are preliminary and the investigation needs to be continued.This inform is about the geological conditions study carried out in Paso Severino zone of the Santa Lucia small river to make a dam to provide water to Montevideo. The techniques used were photo interpretation and general geological studies.

Feasibility study for a muon detector for the CBM experiment

International Nuclear Information System (INIS)

Dutta, Dipanwita; Lebedev, Andrey; Kiseleva, Anna; Ryzhinskiy, Mikhail; Kryshen, Evgeny

2009-01-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR accelerator facility at GSI, Darmstadt is being designed to investigate heavy ion collisions in fixed target mode at beam energies from 10 - 45 A GeV. The major goal is to explore the QCD phase diagram in the region of high baryon densities and at moderate temperatures. One of the proposed key observables is the measurement of charmonium via the dilepton decay channel. As leptons leave the initially produced hot and dense fireball without further interactions, they are excellent probes to study in-medium properties of vector mesons. In this contribution we will present detailed feasibility studies for a di-muon measurement in CBM

Development of Cognitive Bias Modification (CBM) Tools to Promote Adjustment during Reintegration following Deployment

Science.gov (United States)

2017-06-01

a meta-analysis. Child development 73 (3), 916-934. Owen, J.M., 2011. Transdiagnostic cognitive processes in high trait anger. Clinical Psychology ...Award Number: W81XWH-13-2-0001 TITLE: : Development of Cognitive Bias Modification (CBM) Tools to Promote Adjustment during Reintegration...DATES COVERED 15-OCT-2012 TO 14-OCT-2016 4. TITLE AND SUBTITLE Development of Cognitive Bias Modification (CBM) Tools to Promote Adjustment during

Indicadores de desempenho zootécnico observados nas unidades de produção familiar associadas à Cooperativa dos Produtores de Leite de Santa Maria (COOPROL, RS

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Portela Jorge Nunes

2002-01-01

Full Text Available O presente trabalho teve o objetivo de identificar o desempenho zootécnico das unidades de produção familiar (UPFs associadas à Cooperativa dos Produtores de Leite de Santa Maria (COOPROL, RS, que desenvolvem a atividade leiteira combinada ou não com outras atividades vegetal e/ou animal. Foram coletadas as informações de um grupo de 53 UPFs, sendo identificados nove sistemas de produção. Nestes sistemas, a idade média ao primeiro parto (IPP variou de 2,5 a 3 anos, o intervalo entre partos (IEP de 456 a 520 dias, o período seco (PS de 91 a 260 dias, a taxa de natalidade de 70 a 80%, a duração média das lactações (DML de 365 a 387 dias e a produtividade de leite de 2,52 a 13,5 /vaca/dia. Estes valores indicam a necessidade de ações visando readequar o manejo reprodutivo e o sistema alimentar dos rebanhos de cada sistema de produção identificado.

easyCBM Norms. 2014 Edition. Technical Report #1409

Science.gov (United States)

Saven, Jessica L.; Tindal, Gerald; Irvin, P. Shawn; Farley, Dan; Alonzo, Julie

2014-01-01

Previous norms for the easyCBM assessment system were computed using scores from all students who took each measure for every grade and benchmark season (fall, winter, and spring). During the 2013-­14 school year, new national norms were developed to more accurately (proportionately) represent reading and mathematics performance by two variables:…

Development and test of a free-streaming readout chain for the CBM time of flight wall

International Nuclear Information System (INIS)

Loizeau, Pierre-Alain

2014-01-01

This thesis presents the development and test of a free-streaming readout chain for the Time of Flight (TOF) Wall of the Compressed Baryonic Matter (CBM) experiment. In order to contribute to the exploration of the phase diagram of strongly interacting matter, CBM aims at the measurement of rare probes, whose yields and phase space distributions are significantly influenced by their environment. Many of the possible signals, of which the antiprotons was investigated within this thesis, require an excellent Particle Identification (PID) and a new readout paradigm called free-streaming. In CBM, the PID for charged particles is provided by a TOF wall based on Multi-gap Resistive Plate Chambers (MRPC). Within the thesis, a central component of the TOF readout chain, the free-streaming ASIC-TDC, was evaluated and pushed from the prototype level to a close to final design, for which it could be demonstrated that it fulfill all the CBM requirements: resolution, rate capability and stability. Additionally, the CBM TOF software in the CBMROOT software framework was reorganized to merge the processing and analysis of real and simulated data. A data unpacker and a realistic digitizer were implemented with a common output data format. The digitizer was used to estimate the data rates and number of components in a free-streaming readout chain for the full wall.

Selected event reconstruction algorithms for the CBM experiment at FAIR

International Nuclear Information System (INIS)

Lebedev, Semen; Höhne, Claudia; Lebedev, Andrey; Ososkov, Gennady

2014-01-01

Development of fast and efficient event reconstruction algorithms is an important and challenging task in the Compressed Baryonic Matter (CBM) experiment at the future FAIR facility. The event reconstruction algorithms have to process terabytes of input data produced in particle collisions. In this contribution, several event reconstruction algorithms are presented. Optimization of the algorithms in the following CBM detectors are discussed: Ring Imaging Cherenkov (RICH) detector, Transition Radiation Detectors (TRD) and Muon Chamber (MUCH). The ring reconstruction algorithm in the RICH is discussed. In TRD and MUCH track reconstruction algorithms are based on track following and Kalman Filter methods. All algorithms were significantly optimized to achieve maximum speed up and minimum memory consumption. Obtained results showed that a significant speed up factor for all algorithms was achieved and the reconstruction efficiency stays at high level.

CBM Reading, Mathematics, and Written Expression at the Secondary Level: Examining Latent Composite Relations Among Indices and Unique Predictions With a State Achievement Test.

Science.gov (United States)

Codding, Robin S; Petscher, Yaacov; Truckenmiller, Adrea

2015-05-01

A paucity of research has examined the utility of curriculum-based measurement (CBM) for data-based decision making at the secondary level. As schools move to multitiered systems of service delivery, it is conceivable that multiple screening measures will be used that address various academic subject areas. The value of including different CBM indices measures is not well understood. The purpose of this study was to (a) examine the relationship among a variety of reading, writing, and mathematics CBM indices administered to 249 seventh-grade students; (b) investigate amount and patterns of growth; and (c) examine predictive validity to a high-stakes state test using latent factor analysis and multiple indicator growth models. Results indicated strong correspondence among CBM types for fall static scores but weak relationships among slopes. Different patterns of growth were yielded for CBM writing than for CBM reading and mathematics. Findings from this study suggested that although reading, mathematics, and writing CBM were independently and moderately related to both English Language Arts and Math test scores, reading was the strongest predictor when all 3 CBM constructs were considered jointly.

Infecção Hospitalar na visão de enfermeiros da Santa Casa de Bagé - RS

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Marcelo Carneiro

2012-01-01

Full Text Available Hospital Infection(HI is that acquired after patient admission and thatmanifests during hospitalization or after discharge, whenit can be related to the hospital admission or procedures.The objective was to verify the point of view of the nursesof Santa Casa de Caridade de Bagé regarding hospitalinfections. Methods: This was an exploratory studycarried out with 32 nurses from Santa Casa de Caridadede Bagé. Data were collected using the in-depth interviewtechnique from July to August 2010, where the subjectsanswered questions about the association betweeninfection control and nursing care, in which answerswere submitted to the theme content analysis technique.Results: They were divided into three symbolic categories:definition of HI, nurses’ actions regarding HI and thenurses’ perception on HI managers. Conclusion: Theevaluation showed that nurses have a good theoreticalbackground on the subject, as they answered thequestions clearly and appropriately.

Florística e fitossociologia do componente arbóreo de uma floresta ribeirinha, arroio Passo das Tropas, Santa Maria, RS, Brasil Floristic composition and structure of arboreal species in a riverine forest, Passo das Tropas River, Santa Maria, RS, Brazil

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Jean Carlos Budke

2004-09-01

Full Text Available Florestas ribeirinhas são caracterizadas por alta heterogeneidade ambiental, onde diferentes fatores físicos e bióticos regulam o mosaico vegetacional. Embora sejam áreas prioritárias à conservação, devido a sua fragilidade e importância, poucos estudos vêm sendo desenvolvidos nestes ambientes, em especial no Rio Grande do Sul. O objetivo do presente estudo é caracterizar a composição florística e a estrutura fitossociológica de um trecho de floresta ribeirinha em Santa Maria, RS. Para o levantamento, foram demarcadas 100 parcelas de 10x10m cada, dispostas paralelamente ao curso do rio, onde todos os indivíduos arbóreos PAP > 15cm foram amostrados. Foram amostrados 2.195 indivíduos vivos e mais 137 mortos ainda em pé. Os indivíduos vivos pertencem a 57 espécies de 47 gêneros distribuídos em 26 famílias. As espécies com maiores valores de importância foram Gymnanthes concolor Spreng, Sebastiania commersoniana (Baill. Smith & Downs, Eugenia uniflora L., Plinia rivularis (Camb. Rotman e Sebastiania brasiliensis Spreng. O índice de diversidade (H' foi de 2,73 nats/indivíduos e a equabilidade (J' 0,69 nats/indivíduos, valores considerados intermediários em comparação a outros levantamentos. A maioria das espécies amostradas (57% provém do oeste do Estado, características das bacias do Paraná-Uruguai, enquanto que 41% são de ampla distribuição e apenas uma espécie provém do corredor atlântico.Riverine forests have great environmental diversity, where many factors, physical and biotical, play a role on the vegetation mosaic. Although riverine forests are hot spots for conservation, because of their fragility and ecological importance, few studies has been made in these areas, especially in Rio Grande do Sul State. The aim of this work is to determine the floristic composition and the vegetation structure of arboreal species in a riverine forest in Santa Maria municipality. All individuals with PBH > 15 cm were

A First-level Event Selector for the CBM Experiment at FAIR

International Nuclear Information System (INIS)

Cuveland, J de; Lindenstruth, V

2011-01-01

The CBM experiment at the upcoming FAIR accelerator aims to create highest baryon densities in nucleus-nucleus collisions and to explore the properties of super-dense nuclear matter. Event rates of 10 MHz are needed for high-statistics measurements of rare probes, while event selection requires complex global triggers like secondary vertex search. To meet these demands, the CBM experiment uses self-triggered detector front-ends and a data push readout architecture. The First-level Event Selector (FLES) is the central physics selection system in CBM. It receives all hits and performs online event selection on the 1 TByte/s input data stream. The event selection process requires high-throughput event building and full event reconstruction using fast, vectorized track reconstruction algorithms. The current FLES architecture foresees a scalable high-performance computer. To achieve the high throughput and computation efficiency, all available computing devices will have to be used, in particular FPGAs at the first stages of the system and heterogeneous many-core architectures such as CPUs for efficient track reconstruction. A high-throughput network infrastructure and flow control in the system are other key aspects. In this paper, we present the foreseen architecture of the First-level Event Selector.

Utilização do sistema de avaliação do potencial de uso urbano das terras no diagnóstico ambiental do município de Santa Maria - RS

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Pedron Fabrício de Araújo

2006-01-01

Full Text Available A expansão urbana acelerada tem provocado diversos impactos negativos ao ambiente. A necessidade de novas metodologias que permitam um planejamento mais adequado dos recursos naturais é cada dia mais evidente. O objetivo deste trabalho foi realizar um diagnóstico ambiental em áreas urbanas de Santa Maria - RS, determinando-se os conflitos de uso das terras através, do Sistema de Avaliação do Potencial de Uso Urbano das Terras (SAPUT. Foram utilizados produtos e técnicas de sensoriamento remoto e geoprocessamento de imagens. Os problemas de uso indevido das terras identificados estão relacionados com a fragilidade do material geológico e do recurso solo. Até 33% da área vem apresentando utilização acima do seu potencial devido ao seu uso inadequado para construções e agricultura urbana.

Épocas de semeadura do milho com menor risco de ocorrência de deficiência hídrica no município de Santa Maria, RS, Brasil

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Nied Astor Henrique

2005-01-01

Full Text Available Neste trabalho, objetivou-se determinar as épocas de semeadura (ES com menor e maior risco de deficiência hídrica para a cultura do milho no município de Santa Maria (RS. Para isso, utilizaram-se 34 anos de dados, coletados na estação meteorológica de Santa Maria, no cálculo do balanço hídrico (BH seqüencial diário, com base no modelo de Thornthwaite e Mather adaptado. Simularam-se 42 ES, de agosto a fevereiro, para os três grupos de maturação de variedades da cultura. A duração dos subperíodos e do ciclo foi estimada a partir da soma térmica efetiva com temperatura base de 10degreesC. Foi realizado o BH considerando-se a fração de água disponível no solo, abaixo da qual iniciam as deficiências hídricas. A evapotranspiração de referência (ETo foi estimada pelo método de Penman. Verificou-se que nas épocas de semeadura de outubro e novembro e na primeira quinzena de dezembro, as probabilidades de ocorrência de deficiência hídrica são maiores no total do ciclo. As épocas de semeadura de dezembro ao início de janeiro apresentam os menores riscos de deficiência hídrica no período mais crítico para a cultura. Nestas ES, no entanto, deve-se efetivar a semeadura somente se houver condição de umidade no solo adequada para a germinação e emergência.

Distribuição temporal e espacial de anuros em área de Pampa, Santa Maria, RS Temporal and spatial distribution of anurans in the Pampa Region (Santa Maria, RS

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Tiago Gomes dos Santos

2008-06-01

Full Text Available Este estudo teve como objetivo determinar a riqueza, a constância de ocorrência, os modos reprodutivos, o padrão de distribuição da abundância, a temporada de vocalização e testar a correlação das variáveis climáticas sobre a atividade de vocalização dos anuros em uma região do Bioma Pampa, Santa Maria, Rio Grande do Sul. Durante o período de novembro de 2001 a outubro de 2002 foram realizadas coletas mensais empregando o método de ‘busca em sítio de reprodução’ e exame de exemplares depositados na Coleção Herpetológica do Setor de Zoologia da Universidade Federal de Santa Maria (ZUFSM. Foi registrada a ocorrência de 25 espécies de anuros. A anurofauna registrada corresponde a 30% das espécies encontradas no Rio Grande do Sul e normalmente está associada a áreas abertas encontradas no estado e em países vizinhos. Foram registrados quatro modos reprodutivos: modo 1 (14 espécies; 58,3%; modos 11 e 30 (nove espécies; 37,5% e modo 24 (uma espécie; 4,2%. A baixa diversificação de modos reprodutivos provavelmente está relacionada à homogeneidade do hábitat primariamente campestre. A maior parte das espécies mostrou-se constante ou acessória na área estudada e o padrão de distribuição da abundância das espécies apresentou ajuste aos modelos Broken Stick e Log-normal, caracterizados pela homogeneidade na distribuição da abundância das espécies. A maioria das espécies apresentou grande plasticidade na ocupação de hábitats, mas poucas foram plásticas no uso dos sítios de vocalização. Houve correlação positiva, ainda que fraca, da riqueza de espécies com a precipitação mensal acumulada e da abundância com a temperatura média máxima. As correlações obtidas indicaram que na área estudada a temperatura parece atuar mais sobre a abundância de machos em atividade de vocalização e a precipitação sobre a riqueza, apesar da riqueza de espécies ser significativamente maior durante o per

Ring recognition in the CBM RICH detector

International Nuclear Information System (INIS)

Lebedev, S.; Ososkov, G.; Hoehne, C.

2007-01-01

Two algorithms of ring recognition, a standalone ring finder (using only RICH information) and an algorithm based on the information from vertex tracks are described. The fake ring problem and its solution using a set of two-dimensional cuts or an artificial neural network are discussed. Results of a comparative study are given. All developed algorithms were tested on large statistics of simulated events and were then included into the CBM framework for common use

Online Event Reconstruction in the CBM Experiment at FAIR

Science.gov (United States)

Akishina, Valentina; Kisel, Ivan

2018-02-01

Targeting for rare observables, the CBM experiment will operate at high interaction rates of up to 10 MHz, which is unprecedented in heavy-ion experiments so far. It requires a novel free-streaming readout system and a new concept of data processing. The huge data rates of the CBM experiment will be reduced online to the recordable rate before saving the data to the mass storage. Full collision reconstruction and selection will be performed online in a dedicated processor farm. In order to make an efficient event selection online a clean sample of particles has to be provided by the reconstruction package called First Level Event Selection (FLES). The FLES reconstruction and selection package consists of several modules: track finding, track fitting, event building, short-lived particles finding, and event selection. Since detector measurements contain also time information, the event building is done at all stages of the reconstruction process. The input data are distributed within the FLES farm in a form of time-slices. A time-slice is reconstructed in parallel between processor cores. After all tracks of the whole time-slice are found and fitted, they are collected into clusters of tracks originated from common primary vertices, which then are fitted, thus identifying the interaction points. Secondary tracks are associated with primary vertices according to their estimated production time. After that short-lived particles are found and the full event building process is finished. The last stage of the FLES package is a selection of events according to the requested trigger signatures. The event reconstruction procedure and the results of its application to simulated collisions in the CBM detector setup are presented and discussed in detail.

Resíduos sólidos em um sistema de drenagem urbana no município de Santa Maria (RS

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Delmira Beatriz Wolff

2016-03-01

Full Text Available RESUMO Com o crescimento da população e o consequente aumento da urbanização, o lançamento de resíduos sólidos nos sistemas de drenagem urbana tem aumentado nos últimos anos, principalmente nas regiões periféricas das cidades. Este estudo teve como objetivo qualificar e quantificar os resíduos sólidos no arroio Cancela-Tamandai, localizado em área urbana, no município de Santa Maria (RS. Foram coletados ao todo 1.153,2 kg de resíduos sólidos com uma precipitação pluviométrica total para o período de novembro de 2012 a janeiro de 2013 de 518,94 mm, sendo, desses, 93,9% composto por matéria orgânica, sendo a maioria vegetação. O arroio Cancela-Tamandai apresentou uma carga de resíduos sólidos igual a 17,27 ou 0,424 kg.hab-1.ano-1. A curva de previsão de resíduos sólidos orgânicos drenados em função da precipitação pluviométrica apresentou correlação de 76,4%, um parâmetro importante para a tomada de decisão dos gestores municipais em relação aos resíduos sólidos gerados. Assim, conceber estratégias para o monitoramento desses resíduos representa passo importante na busca de soluções que visem um melhor gerenciamento de bacias hidrográficas urbanas.

Performance of high-rate TRD prototypes for the CBM experiment in test beam and simulation

Energy Technology Data Exchange (ETDEWEB)

Klein-Boesing, Melanie [Institut fuer Kernphysik, Muenster (Germany)

2008-07-01

The goal of the future Compressed Baryonic Matter (CBM) experiment is to explore the QCD phase diagram in the region of high baryon densities not covered by other experiments. Among other detectors, it will employ a Transition Radiation Detector (TRD) for tracking of charged particles and electron identification. To meet the demands for tracking and for electron identification at large particle densities and very high interaction rates, high efficiency TRD prototypes have been developed. These prototypes with double-sided pad plane electrodes based on Multiwire Proportional Chambers (MWPC) have been tested at GSI and implemented in the simulation framework of CBM. Results of the performance in a test beam and in simulations are shown. In addition, we present a study of the performance of CBM for electron identification and dilepton reconstruction with this new detector layout.

THE LINGUISTIC CONTACT IN SERRA DOS TAPES, RS: IMPLICATIONS TO BRAZILIAN PORTUGUESE TEACHING WITH POMERANIAN MAINTENANCE

OpenAIRE

Luís Isaías Centeno do Amaral; Daiane Mackedanz

2016-01-01

This paper is the result of a study with a pre-school group, in the Primary School Martinho Lutero, located in Santa Augusta city, RS. We aim to promote thoughts towards to Pomerano and Brazilian Portuguese linguistic contact; more specifically, since the adoption of a more culturally sensitive pedagogy to students sociolinguistics specificities influences Portuguese teaching process, considering that most of the half analyzed joined school or as Pomerano monolingual or as Pomerano/ Por...

Exceptional longevity and muscle and fitness related genotypes: a functional in vitro analysis and case-control association replication study with SNPs THRH rs7832552, IL6 rs1800795 and ACSL1 rs6552828

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Noriyuki eFuku

2015-05-01

Full Text Available There are several gene variants that are candidates to influence functional capacity in long-lived individuals. As such, their potential association with exceptional longevity (EL, i.e., reaching 100+ years deserves analysis. Among them are rs7832552 in the thyrotropin-releasing hormone receptor (TRHR gene, rs1800795 in the interleukin-6 (IL6 gene and rs6552828 in the coenzyme A synthetase long-chain 1 (ACSL1 gene. To gain insight into their functionality (which is yet unknown, here we determined for the first time luciferase gene reporter activity at the muscle tissue level in rs7832552 and rs6552828. We then compared allele/genotype frequencies of the 3 abovementioned variants among centenarians [n=138, age range 100-111 years (114 women] and healthy controls [n=334, 20-50 years (141 women] of the same ethnic and geographic origin (Spain. We also studied healthy centenarians [n=79, 100-104 years (40 women] and controls [n=316, 27-81 years (156 women] from Italy, and centenarians [n=742, 100-116 years (623 women] and healthy controls [n=499, 23-59 years (356 women] from Japan. The THRH rs7832552 T-allele and ACSL1 rs6552828 A-allele up-regulated luciferase activity compared to the C and G-allele, respectively (P≤0.001. Yet we found no significant association of EL with rs7832552, rs1800795 or rs6552828 in any of the 3 cohorts. Further research is needed with larger cohorts of centenarians of different origin as well as with younger old people.

A gestão socioambiental em uma empresa de transporte coletivo urbano no município de Santa Maria-RS / Environmental management in a company of urban collective transport in the city of Santa Maria-RS

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Luiz Antonio Rossi de Freitas

2013-08-01

Full Text Available É notável o compromisso das empresas com posturas socialmente corretas, ambientalmente sustentáveis e economicamente viáveis em suas práticas de gestão. É neste sentido que a responsabilidade socioambiental torna-se uma variável importante na estratégia competitiva das empresas para que estas procurem atingir e demonstrar para a sociedade um desempenho ambiental correto, controlando os impactos no meio ambiente. Assim, no que tange às políticas públicas dos transportes, as empresas privadas, que detêm a concessão dos serviços dos transportes urbanos, precisam adotar medidas que vão além do mero cumprimento legal exigido pelos órgãos reguladores e fiscalizadores, adotando práticas de responsabilidade social e ambiental que minimizem os impactos negativos e melhorem a qualidade dos serviços de transportes prestados. É neste sentido que se torna relevante o estudo das práticas de responsabilidade socioambientais da empresa de transporte em estudo. A crescente valorização das questões ambientais deve estar adequada à legislação, às demandas sociais e alinhada à estratégia da organização. Neste sentido, a presente pesquisa estuda a gestão socioambiental adotada em uma empresa de transporte coletivo urbana na cidade de Santa Maria, RS; especificamente pretende verificar as práticas de gestão em relação às questões ambientais e sociais, bem como o seu alinhamento com a estratégia empresarial. Sendo assim, trata-se de uma pesquisa exploratória, que se utiliza do estudo de caso por tratar-se de um conhecimento profundo e exaustivo de um único objeto. Assim, o desenvolvimento desse estudo busca a definição de um conjunto de dados que deverão auxiliar o processo de descrição de fases ou totalidade do processo social da empresa MEDIANEIRA TRANSPORTES LTDA. As conclusões limitam-se ao contexto unicamente da empresa, indicando que as estratégias de sustentabilidade estão alinhadas à filosofia de neg

The idea of Santa Claus in terms of Cognitive Sciences. Cultural persistence and interference with the Christian Religion

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PhD. Paul SCARLAT

2017-01-01

Full Text Available The idea of Santa Claus is a universal one, which has been carried on for generations despite many obstacles. Although related to fantasy and imagination, he belongs to all cultures and for children he maintains a real presence. Cognitive Science examines the idea of this mysterious individual and brings clarification to his existence in society. Because this “superhero” plays a part in society, he needs a mental structure that can be imagined, a particular and specific cognitive structure. The study identifies the cognitive mechanisms by which the idea of Santa Claus is generated. The history of Santa has interfered with religion since ancient times. He is sometimes confused with religious figures. Cognitive Sciences as applied to religion seem to confirm the universality of religious beliefs and a certain similarity between the idea of Santa Claus and that of holy persons, such as St. Nicholas. However, there are opinions within this field of research that differentiate between the two areas: fantastic and religious.

The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067.

Science.gov (United States)

Schnitzler, Fabian; Friedrich, Matthias; Wolf, Christiane; Angelberger, Marianne; Diegelmann, Julia; Olszak, Torsten; Beigel, Florian; Tillack, Cornelia; Stallhofer, Johannes; Göke, Burkhard; Glas, Jürgen; Lohse, Peter; Brand, Stephan

2014-01-01

Very recently, a sub-analysis of genome-wide association scans revealed that the non-coding single nucleotide polymorphism (SNP) rs12212067 in the FOXO3A gene is associated with a milder course of Crohn's disease (CD) (Cell 2013;155:57-69). The aim of our study was to evaluate the clinical value of the SNP rs12212067 in predicting the severity of CD by correlating CD patient genotype status with the most relevant complications of CD such as stenoses, fistulas, and CD-related surgery. We genotyped 550 CD patients for rs12212067 (FOXO3A) and the three common CD-associated NOD2 mutations rs2066844, rs2066847, and rs2066847 and performed genotype-phenotype analyses. No significant phenotypic differences were found between the wild-type genotype TT of the FOXO3A SNP rs12212067 and the minor genotypes TG and GG independently from NOD2 variants. The allele frequency of the minor G allele was 12.7%. Age at diagnosis, disease duration, body mass index, surgery rate, stenoses, fistula, need for immunosuppressive therapy, and disease course were not significantly different. In contrast, the NOD2 mutant p.Leu1007fsX1008 (rs2066847) was highly associated with penetrating CD (p = 0.01), the development of fistulas (p = 0.01) and stenoses (p = 0.01), and ileal disease localization (p = 0.03). Importantly, the NOD2 SNP rs2066847 was a strong separator between an aggressive and a mild course of CD (p = 2.99×10(-5)), while the FOXO3A SNP rs12212067 did not separate between mild and aggressive CD behavior in our cohort (p = 0.35). 96.2% of the homozygous NOD2 p.Leu1007fsX1008 carriers had an aggressive disease behavior compared to 69.3% of the patients with the NOD2 wild-type genotype (p = 0.007). In clinical practice, the NOD2 variant p.Leu1007fsX1008 (rs2066847), in particular in homozygous form, is a much stronger marker for a severe clinical phenotype than the FOXO3A rs12212067 SNP for a mild disease course on an individual patient level despite its

Successful engagement: CBM's holistic approach to the work in the area of ear care, deafness, hard of hearing and deafblindness.

Science.gov (United States)

Tesni, Sian; Santana-Hernández, Diego

2014-09-01

CBM is an international Christian development organisation, committed to improving the quality of life of persons with disabilities in disadvantaged societies. CBM aims at achieving this in partnership with local organisations and in cooperation with stakeholders at regional and international levels. This article aims at sharing CBM's holistic approach for successful engagement in the work area of ear care, deafness, hard of hearing and deafblindness. Review of CBM supporting documents, including strategies, position papers, technical guidelines, criteria of success and information related to partners, centres of excellence and model projects. Description of how partner programmes use participatory methods of planning and implementation, involving persons with disabilities and the community. Recommendations on how to develop national or sub-national strategies to impact the lives, and advocate with governments for the rights and inclusion, of persons with disabilities. CBM's holistic approach to work in the area of ear care; deafness; hard of hearing and deafblindness includes intervention at all levels of health care provision, Education, CBR and Audiological, Speech Therapy and other interdisciplinary services. This article presents CBM's core principles and shares specific strategic planning and results, together with lessons learnt while searching a sustainable engagement for field work. Rehabilitation, in its widest conception, should be approached as a multidisciplinary strategy, and developed in close cooperation with other local, national and international agencies. CBM is positioned in a strategic point from where it can play a key role in the facilitation of an international forum for agencies and stakeholders to reach a consensus to decrease the burden of ear disease and hearing loss, through early intervention and re/habilitation.

The read-out chain of the CBM STS detector

Energy Technology Data Exchange (ETDEWEB)

Lehnert, Joerg; Emschermann, David [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH (Germany); Collaboration: CBM-Collaboration

2016-07-01

The Compressed Baryonic Matter (CBM) experiment at FAIR will explore the QCD phase diagram at high baryon densities during nucleus-nucleus collisions in a fixed target setup. Its physics goals require interaction rates up to 10 MHz, which can be exploited with fast and radiation hard detectors equipped with free-streaming front-end and readout electronics, connected to a common Data Aquisition (DAQ) system to forward data to the First Level Event Selector (FLES). The core component of the CBM DAQ system is the Data Processing Board (DPB) implementing three important functionalities: - The incoming data via multiple lower-speed, short distance links is preprocessed, concentrated and forwarded to the FLES via higher-speed, long distance links. - The DPBs provide an interface for the Detector Control System (DCS) to configure readout and front-end electronics (FEE). - As part of the Timing and Fast Control (TFC) system the DPBs ensure transmission of the reference clock and synchronous commands necessary to synchronize the FEE. This contribution presents the readout and DAQ chain on the example of the core subdetector, the Silicon Tracking System (STS).

Making the Good Even Better: Feedback from easyCBM Focus Groups, School Year 2009/2010. Technical Report # 1001

Science.gov (United States)

Alonzo, Julie; Tindal, Gerald; Lai, Cheng-Fei

2010-01-01

This technical report provides a summary of feedback from teachers, administrators, and support personnel who used the easyCBM progress monitoring and benchmark assessment system during school year 2009/2010. Data were gathered from semi-structured focus groups conducted during the 2010 easyCBM August Institute at the University of Oregon. Results…

Fast parallel ring recognition algorithm in the RICH detector of the CBM experiment at FAIR

International Nuclear Information System (INIS)

Lebedev, S.

2011-01-01

The Compressed Baryonic Matter (CBM)experiment at the future FAIR facility at Darmstadt will measure dileptons emitted from the hot and dense phase in heavy ion collisions. In case of an electron measurement, a high purity of identified electrons is required in order to suppress the background. Electron identification in CBM will be performed by a Ring Imaging Cherenkov (RICH) detector and Transition Radiation Detector (TRD). Very fast data reconstruction is extremely important for CBM because of the huge amount of data which has to be handled. In this contribution, a parallelized ring recognition algorithm is presented. Modern CPUs have two features, which enable parallel programming. First, the SSE technology allows using the SIMD execution model. Second, multicore CPUs enable the use of multithreading. Both features have been implemented in the ring reconstruction of the RICH detector. A considerable speedup factor from 357 to 2.5 ms/event has been achieved including preceding code optimization for Intel Xeon X5550 processors at 2.67 GHz

REESTRUTURAÇÃO NO PROJETO EDUCAÇÃO PATRIMONIAL EM ESCOLAS MUNICIPAIS DE SANTA VITÓRIA DO PALMAR, RS – BRASIL

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Viviane Rocha Teixeira

2016-12-01

Full Text Available O presente trabalho surgiu de uma nova análise que foi feita através de observação participante dos membros do grupo PET (Programa de Educação Tutorial Turismo. Identificou-se a necessidade de uma reestruturação no projeto Educação Patrimonial para adequar-se melhor ao perfil das crianças. Assim, como principais resultados, diminuiu-se o número de encontros visando otimizar o tempo e foi realizada algumas modificações como o aumento do tempo de realização de atividades que favorecem a interação entre estudantes. O objetivo deste trabalho é descrever como se efetuou a reestruturação no projeto Educação Patrimonial em escolas municipais de Santa Vitória do Palmar, RS – Brasil. O projeto, que tem como sujeitos crianças do 5º ano, propõem-se a sensibilizá-las e que essas multipliquem os conhecimentos construídos com os adultos (familiares, vizinhos, amigos, entre outros. Acredita-se que pode contribuir, também, em relação ao incremento do turismo histórico-cultural e de lazer na cidade. Para a coleta de dados foi utilizado o método de observação participante e uma pesquisa bibliográfica em trabalhos do próprio Grupo PET. Na análise dos resultados encontra-se a descrição detalhada da reestrputuração do projeto e a justificativa da modificação da estrutura. Palavras-chave: Patrimônio.  Turismo.  Reestruturação.

The miR-449b polymorphism, rs10061133 A>G, is associated with premature ovarian insufficiency.

Science.gov (United States)

Pan, Hong; Chen, Beili; Wang, Jing; Wang, Xi; Hu, Ping; Wu, Shinan; Liu, Yunyun; Xu, Zuying; Zhang, Wei; Wang, Binbin; Cao, Yunxia

2016-09-01

To determine if the miR-449b polymorphism, rs10061133 A>G, is associated with premature ovarian insufficiency (POI) pathogenesis. From January 2011 to December 2014, a total of 148 individuals with POI and 225 age-matched controls were collected from the Center for Reproductive Medicine, 1st Affiliated Hospital of Anhui Medical University (Hefei, China). Genotyping of miR-449b rs1006113 was performed using matrix-assisted laser desorption ionization time-of-flight-based mass spectrometry. Rs10061133 A>G is a highly conserved SNP locus in the mature area of miR-449b. Association analysis shows that the rs10061133 AA genotype is a risk factor for POI. Our study provides the first evidence that the miR-449b rs10061133 AA genotype is associated with POI risk.

PCSK1 rs6232 Is Associated with Childhood and Adult Class III Obesity in the Mexican Population

Science.gov (United States)

Villalobos-Comparán, Marisela; Villamil-Ramírez, Hugo; Villarreal-Molina, Teresa; Larrieta-Carrasco, Elena; León-Mimila, Paola; Romero-Hidalgo, Sandra; Jacobo-Albavera, Leonor; Liceaga-Fuentes, Adriana E.; Campos-Pérez, Francisco J.; López-Contreras, Blanca E.; Tusié-Luna, Teresa; del Río-Navarro, Blanca E.; Aguilar-Salinas, Carlos A.; Canizales-Quinteros, Samuel

2012-01-01

Background Common variants rs6232 and rs6235 in the PCSK1 gene have been associated with obesity in European populations. We aimed to evaluate the contribution of these variants to obesity and related traits in Mexican children and adults. Methodology/Principal Findings Rs6232 and rs6235 were genotyped in 2382 individuals, 1206 children and 1176 adults. Minor allele frequencies were 0.78% for rs6232 and 19.99% for rs6235. Rs6232 was significantly associated with childhood obesity and adult class III obesity (OR = 3.01 95%CI 1.64–5.53; P = 4×10−4 in the combined analysis). In addition, this SNP was significantly associated with lower fasting glucose levels (P = 0.01) and with increased insulin levels and HOMA-B (P = 0.05 and 0.01, respectively) only in non-obese children. In contrast, rs6235 showed no significant association with obesity or with glucose homeostasis parameters in any group. Conclusion/Significance Although rs6232 is rare in the Mexican population, it should be considered as an important risk factor for extreme forms of obesity. PMID:22737226

The occupational health of Santa Claus

OpenAIRE

Straube, Sebastian; Fan, Xiangning

2015-01-01

Previous publications in the field of Santa studies have not focused on health and safety issues arising from Santa?s workplace activities. However, it should be acknowledged that unique occupational hazards exist for Santa Claus. Major occupational health issues affecting Santa are discussed, along with suggestions for future research directions.

The NOD2 p.Leu1007fsX1008 mutation (rs2066847 is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067.

Directory of Open Access Journals (Sweden)

Fabian Schnitzler

Full Text Available Very recently, a sub-analysis of genome-wide association scans revealed that the non-coding single nucleotide polymorphism (SNP rs12212067 in the FOXO3A gene is associated with a milder course of Crohn's disease (CD (Cell 2013;155:57-69. The aim of our study was to evaluate the clinical value of the SNP rs12212067 in predicting the severity of CD by correlating CD patient genotype status with the most relevant complications of CD such as stenoses, fistulas, and CD-related surgery.We genotyped 550 CD patients for rs12212067 (FOXO3A and the three common CD-associated NOD2 mutations rs2066844, rs2066847, and rs2066847 and performed genotype-phenotype analyses.No significant phenotypic differences were found between the wild-type genotype TT of the FOXO3A SNP rs12212067 and the minor genotypes TG and GG independently from NOD2 variants. The allele frequency of the minor G allele was 12.7%. Age at diagnosis, disease duration, body mass index, surgery rate, stenoses, fistula, need for immunosuppressive therapy, and disease course were not significantly different. In contrast, the NOD2 mutant p.Leu1007fsX1008 (rs2066847 was highly associated with penetrating CD (p = 0.01, the development of fistulas (p = 0.01 and stenoses (p = 0.01, and ileal disease localization (p = 0.03. Importantly, the NOD2 SNP rs2066847 was a strong separator between an aggressive and a mild course of CD (p = 2.99×10(-5, while the FOXO3A SNP rs12212067 did not separate between mild and aggressive CD behavior in our cohort (p = 0.35. 96.2% of the homozygous NOD2 p.Leu1007fsX1008 carriers had an aggressive disease behavior compared to 69.3% of the patients with the NOD2 wild-type genotype (p = 0.007.In clinical practice, the NOD2 variant p.Leu1007fsX1008 (rs2066847, in particular in homozygous form, is a much stronger marker for a severe clinical phenotype than the FOXO3A rs12212067 SNP for a mild disease course on an individual patient level despite

Status and first Results of the CBM TRD Prototype Development

International Nuclear Information System (INIS)

Arend, Andreas

2013-01-01

The measurement of decay products from rare particles in the CBM experiment defines the requirements for the used detector systems. This report describes the approaches for the Transition Radiation Detector to fulfil these requirements and presents the current status of the prototype development. First results from beam tests with these prototypes are discussed.

Association of TNF-α rs1799964 and IL-1β rs16944 polymorphisms with multiple system atrophy in Chinese Han population.

Science.gov (United States)

Zhou, Xin; Wang, Chunrong; Chen, Zhao; Peng, Yun; Peng, Huirong; Hou, Xuan; Ye, Wei; Qiu, Rong; Xia, Kun; Tang, Beisha; Jiang, Hong

2018-01-07

Recent evidence suggested that several single nucleotide polymorphisms (SNPs) of inflammation-related genes (TNF-α rs1799964, IL-1α rs1800587, IL-1β rs16944, IL-8 rs4073, ICAM-1 rs5498) were associated with multiple system atrophy (MSA). Herein, we conducted this case-control study to evaluate the possible correlation between the five SNPs related to inflammation and MSA in Chinese Han population. We recruited 154 sporadic patients with MSA and 223 health controls in this study. All subjects were genotyped for the five SNPs using polymerase chain reaction amplification and Sanger sequencing. TNF-α rs1799964, genotype distribution and minor allele frequency (MAF) showed significant differences between patients and controls, which might illustrate the minor allele C may increase the risk for MSA (genotype, P = 0.006, OR = 1.245, 95% CI = [1.066-1.455]; allele, P = 0.001, OR = 1.887, 95% CI = [1.303-2.733]). For rs16944, patients carrying AA genotype showed a nearly 5-year early age at onset (AAO) than GG genotype (50.52 ± 7.45 years vs. 54.90 ± 7.21 years, P = 0.037). No differences were found in genotype distribution and MAF of the five SNPs between patients with MSA with predominant cerebellar ataxia (MSA-C) and with predominant Parkinsonism (MSA-P). Our study suggests that rs1799964 of TNF-α may act as a risk factor for MSA and the IL-1β rs16944 might be a genetic factor that modifies the AAO in MSA. Moreover, the exact mechanism of neuroinflammatory response in MSA deserves further exploration.

easyCBM CCSS Math Item Scaling and Test Form Revision (2012-2013): Grades 6-8. Technical Report #1313

Science.gov (United States)

Anderson, Daniel; Alonzo, Julie; Tindal, Gerald

2012-01-01

The purpose of this technical report is to document the piloting and scaling of new easyCBM mathematics test items aligned with the Common Core State Standards (CCSS) and to describe the process used to revise and supplement the 2012 research version easyCBM CCSS math tests in Grades 6-8. For all operational 2012 research version test forms (10…

Use of design as competitive advantage in the furniture industry at Santa Maria/RS

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Leoni Pentiado Godoy

2012-08-01

Full Text Available This article shows the contribution of innovative and proactive professional design to increase the competitiveness of the supply chain sector. Thus, the question that motivates the study were: how the design as a strategy, aligned to quality, can act as a competitive to micro and small enterprise in the furniture sector? The study conducted individual interviews with furniture industry managers and used questionnaires to furniture consumers in Santa Maria, located in the center of Rio Grande do Sul State. The research has shown that the search for mechanisms that create competition between companies is increasingly intense and the race for innovative methods to achieve efficiency has great importance. The design adds value to product in terms of aesthetics, ergonomics, comfort and functionality, besides being a very important element in the rationalization of production

Density functional study of CaN mono and bilayer on Cu(001)

International Nuclear Information System (INIS)

Zahedifar, Maedeh; Hashemifar, S. Javad; Akbarzadeh, Hadi

2014-01-01

Density functional - pseudopotential calculations are performed to provide first-principles insights into magnetic behaviour of bulk CaN and CaN monolayers on Cu(001) in the rock-salt (RS) and zinc-blende (ZB) structures. Our results indicate that both RS- and ZB-CaN exhibit half-metallic ferromagnetism originated from the incomplete 2p shell of the nitrogen ion. In contrast to the bulk CaN, the CaN monolayers on Cu(001) generally favor ZB structure. We argue that the more stable ZB-CaN thin films on Cu(001) are nonmagnetic, because of strong Cu-N bonding at the interface, while the less stable Ca terminated ZB-CaN thin films exhibit half-metallic ferromagnetism. The transition path between the high energy ferromagnetic and the stable nonmagnetic configurations of the ZB-CaN monolayer on Cu(001) are studied by using the nudged elastic band method. We observe a two stages transition and an activation barrier of about 1.18 eV in the minimum energy path of this transition

MP CBM-Z V1.0: design for a new CBM-Z gas-phase chemical mechanism architecture for next generation processors

OpenAIRE

Wang, Hui; Lin, Junmin; Wu, Qizhong; Chen, Huansheng; Tang, Xiao; Wang, Zifa; Chen, Xueshun; Cheng, Huaqiong; Wang, Lanning

2018-01-01

Precise and rapid air quality simulation and forecasting are limited by the computation performance of the air quality model, and the gas-phase chemistry module is the most time-consuming function in the air quality model. In this study, we designed a new framework for the widely used Carbon Bond Mechanism Z (CBM-Z) gas-phase chemical kinetics kernel to adapt the Single Instruction Multiple Data (SIMD) technology in the next-generation processors for improving its calculation performance. The...

Sistemas de previsão de requeima em cultivos de batata em Santa Maria, RS Forecast systems of late blight in potato crops in Santa Maria, Rio Grande do Sul State, Brazil

Directory of Open Access Journals (Sweden)

Leosane Cristina Bosco

2010-01-01

Full Text Available Os sistemas de previsão constituem alternativa para o controle eficiente da requeima em batata e consequente redução da quantidade de fungicidas utilizados, dos custos de produção e da poluição ambiental. O objetivo deste trabalho foi avaliar os sistemas de previsão de ocorrência de requeima, Blitecast e Prophy, em cultivos de primavera e outono de batata, cultivar Macaca, suscetível a requeima, na região produtora de Santa Maria (RS. Os experimentos foram desenvolvidos na primavera de 2006 e outono de 2007 com a cultivar Macaca. Os dados meteorológicos foram coletados no centro da área experimental com uma estação automática e com psicrômetros instalados em diferentes níveis. Os tratamentos foram arranjados no delineamento inteiramente casualizado, com quatro repetições, sendo diferenciados por meio dos valores de severidade acumulados, calculados pelos sistemas de previsão Blitecast e Prophy. Os valores de severidade acumulados foram utilizados como indicadores do momento de aplicação de fungicida para o controle da requeima. Verificou-se que a utilização do sistema de previsão de requeima Prophy, com acúmulo de 15, 20 ou 25 valores de severidade e do sistema Blitecast com 24 valores de severidade acumulados, para o genótipo de batata suscetível, Macaca, permite reduzir o número de aplicações de fungicidas sem afetar significativamente a produtividade de tubérculos comerciais.The forecast systems are an alternative to the efficient control of late blight potatoes and consequent reduction in the amount of fungicide and thereby reduce production costs and environmental pollution. The objective of this study was to evaluate forecast systems, Blitecast and Prophy, for late blight occurrence in Macaca potato cultivar in Santa Maria, Rio Grande do Sul State, Brazil. The experiments were carried out during Spring 2006 and Autumn 2007 with the Macaca cultivar characterized as susceptible to late blight. Meteorological

No relationship between most polymorphisms of steroidogenic acute regulatory (StAR gene with polycystic ovarian syndrome

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Azadeh-Sadat Nazouri

2015-12-01

Full Text Available Background: Polycystic ovary syndrome (PCOS is one of the most common endocrine women’s disorders in reproductive age. Hyperandrogenism has a critical role in the etiology of PCOS and it can cause fault in Steroidogenesis process. During steroidogenesis, steroidogenic acute regulatory protein (StAR seems to increase the delivery of cholesterol through mitochondrial membrane. Therefore, polymorphisms of StAR might effect on this protein and play a role in the etiology of PCOS. Objective: The aim of this study was to investigate the association between StAR SNPs with PCOS. Thus, seven polymorphisms in this gene: rs104894086, rs104894089, rs104894090, rs137852689, rs10489487, rs104894085 were detected. Materials and Methods: In this case control study, 45 PCOS women, 40 male factor/unexplained infertile women, and 40 fertile women as two control groups were participated from 2008-2012. Polymorphisms were detected using restriction fragment length polymorphism (PCR-RFLP method. Results: Heterozygote genotyping for rs137852689 SNP (amino acid 218 C > T was only seen in seven PCOS patients, one in normal ovulatory women, and five in male factor/unexplained infertile women (15.5%, 2.5%, 12.5%, respectively (p= 0.12. While, it has shown no association between other SNPS with PCOs. Conclusion: The RFLP results for seven chosen SNPs, which located in exon 5 and 7 showed normal status in three groups, it means no heterozygous or homozygous forms of selected SNPs were observed. So, it seems evaluation of the active amino acid sites should be investigated and also the study population should be increased.

The silicon tracking system of the CBM experiment

Energy Technology Data Exchange (ETDEWEB)

Balog, Tomas [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Collaboration: CBM-Collaboration

2014-07-01

The Compressed Baryonic Matter (CBM) experiment at FAIR will explore the phase diagram of strongly interacting matter at the highest net-baryon densities in nucleus-nucleus collisions with interaction rates up to 10 MHz. As the core tracking detector of CBM the Silicon Tracking System (STS) will be installed in the gap of the 1 T super conducting dipole magnet for reconstruction of charged particle trajectories and its momenta. The requirement on momentum resolution, Δp/p=1%, can only be achieved with an ultra-low material budget, imposing particular restrictions on the location of 2.5 million channel front-end electronics dissipating 40 KW in the fiducial volume of about 2 m{sup 3}. The concept of the STS is based on a modular structure containing 300 μm thick double-sided silicon microstrip sensors read out through ultra-thin multi-line micro-cables with fast self-triggering electronics. As central building blocks the modules consisting of each a sensor, micro-cable and front-end electronics will be mounted with lightweight carbon fiber support structures onto 8 detector stations. At the station periphery infrastructure such as power and cooling lines will be placed. The status of the STS development is summarized in the presentation, including an overview on sensors, read-out electronics, prototypes, and system integration.

Tendências das séries históricas do índice de calor no município de Santa Maria - RS

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Stefanía Dalmolin da Silva

2014-01-01

Full Text Available Este trabalho teve como objetivo calcular e analisar as séries históricas mensais do Índice de Calor (IC para Santa Maria, RS, Brasil, no período de 1968 a 2011. As variáveis meteorológicas utilizadas neste trabalho foram pressão atmosférica, temperatura do bulbo seco e temperatura do bulbo úmido, no horário das 9h (12UTC, 15h (18UTC e 21h (00UTC. Foi realizada análise de tendência das séries históricas para o valor absoluto e a média mensais do IC através do teste de Mann-Kendall e análise de regressão linear simples para quantificar a tendência, com nível de significância de 95% (α=0,05. Para o valor máximo, no horário das 15h (18UTC, as séries históricas para os meses de janeiro e abril apresentaram acréscimo no valor do índice de calor na magnitude de 0,76°C década-1 e 0,92°C década-1, respectivamente. No horário das 21h (00 UTC, os meses de abril e novembro apresentaram aumento de 0,43°C década-1 e 0,55°C década-1, respectivamente. Porém os meses de maio e agosto apresentaram diminuição de 0,69°C década-1 e 0,31°C década-1, respectivamente.

Distributions of energy losses of electrons and pions in the CBM TRD

International Nuclear Information System (INIS)

Akishina, E.P.; Akishina, T.P.; Ivanov, V.V.; Denisova, O.Yu.

2007-01-01

The distributions of energy losses of electrons and pions in the TRD detector of the CBM experiment are considered. We analyze the measurements of the energy deposits in one-layer TRD prototype obtained during the test beam (GSI, Darmstadt, February 2006) and Monte Carlo simulations for the n-layered TRD realized with the help of GEANT in frames of the CBM ROOT. We show that 1) energy losses both for real measurements and GEANT simulations are approximated with a high accuracy by a log-normal distribution for π and a weighted sum of two log-normal distributions for e; 2) GEANT simulations noticeably differ from real measurements and, as a result, we have a significant loss in the efficiency of the e/π identification. A procedure to control and correct the process of the energy deposit of electrons in the TRD is developed

Towards self-triggered digitization and data readout in the CBM time-of-flight system

Energy Technology Data Exchange (ETDEWEB)

Simon, Christian; Herrmann, Norbert [Physikalisches Institut und Fakultaet fuer Physik und Astronomie, Ruprecht-Karls-Universitaet Heidelberg, 69120 Heidelberg (Germany); Collaboration: CBM-Collaboration

2015-07-01

The design goal of the future Compressed Baryonic Matter (CBM) experiment is to measure rare probes of dense strongly interacting matter with an unprecedented accuracy. Target interaction rates of up to 10 MHz for heavy systems like Au+Au and the need to identify experimental signatures of probes like multi-strange hyperons in the online data stream place challenging demands on the experiment's data acquisition system. Each detector subsystem in CBM implements a self-triggered digitization and readout chain fitted to the respective front-end electronics sending continuous data streams to a high-performance computing farm called the First-Level Event Selector (FLES). Here, events are reconstructed online to identify the physically most interesting ones as only a fraction of the enormous data rate (up to 1 TB/s) can be stored permanently for later offline analysis. The time-of-flight (TOF) wall of CBM is composed of high-resolution timing multi-gap resistive plate chambers (MRPCs) which are estimated to deliver signal rates of up to 500 kHz per electronics channel. Prototypical readout schemes currently under test which are able to transport this high payload are presented, and an outline towards inclusion in the FLES network is given.

Aligning PHM, SHM and CBM by understanding the physical system failure behaviour

NARCIS (Netherlands)

Tinga, Tiedo; Loendersloot, Richard; Bregon, A.; Daigle, M.J.

2014-01-01

In this work the three disciplines of condition based maintenance (CBM), structural health monitoring (SHM) and prognostics and health management (PHM) are described and the characteristics of the disciplines are compared. The three approaches are then demonstrated using three different case studies

Communication of work accidents involving biological material: a study in the city of Santa Cruz do Sul/RS

OpenAIRE

Dayane Diehl; Karini da Rosa; Susimar Souza Rosa; Susane Beatriz Frantz Krug

2012-01-01

Rationale and Objectives: Healthcare workers are constantly exposed to the risk of occupational accidents involving biological material. Thus the aim of the study was to develop a profile of workers involved in workplace accidents with biological materials in Santa Cruz do Sul, through the number of notifications made in information systems. Methods: Transversal retrospective study with a quantitative approach; data collection was carried out between the years 2008 and 2010 from medical recor...

Ring recognition and electron identification in the RICH detector of the CBM experiment at FAIR

International Nuclear Information System (INIS)

Lebedev, S; Hoehne, C; Ososkov, G

2010-01-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR facility at Darmstadt will measure dileptons emitted from the hot and dense phase in heavy-ion collisions. In case of an electron measurement, a high purity of identified electrons is required in order to suppress the background. Electron identification in CBM will be performed by a Ring Imaging Cherenkov (RICH) detector and Transition Radiation Detectors (TRD). In this contribution we will present algorithms and software which have been developed for electron identification in CBM. Efficient and fast ring recognition in the RICH detector is based on the Hough Transform method which has been accelerated considerably compared to a standard implementation. Ring quality selection is done using an Artificial Neural Network which also has been used for electron identification. Due to optical distortions ellipse fitting and radius corre ction routines are used for improved ring radius resolution. These methods allow for a high purity and efficiency of reconstructed electron rings. For momenta above 2 GeV/c the ring reconstruction efficiency for electrons embedded in central Au+Au collisions at 25 AGeV beam energy is 95% resulting in an electron identification efficiency of 90% at a pion suppression factor of 500. Including information from the TRD a pion suppression of 10 4 is reached at 80% efficiency. The developed algorithm is very robust to a high ring density environment. Current work focusses on detector layout studies in order to optimize the detector setup while keeping a high performance. All developed algorithms were tested on large statistics of simulated events and are included into the CBM software framework for common use.

Associations of polymorphisms in the cytokine genes IL1β (rs16944), IL6 (rs1800795), IL12b (rs3212227) and growth factor VEGFA (rs2010963) with anthracosilicosis in coal miners in Russia and related genotoxic effects.

Science.gov (United States)

Volobaev, Valentin P; Larionov, Aleksey V; Kalyuzhnaya, Ekaterina E; Serdyukova, Ekaterina S; Yakovleva, Svetlana; Druzhinin, Vladimir G; Babich, Olga O; Hill, Elena G; Semenihin, Victor A; Panev, Nikolay I; Minina, Varvara I; Sivanesan, Saravana Devi; Naoghare, Pravin; da Silva, Juliana; Barcelos, Gustavo R M; Prosekov, Alexander Y

2018-04-13

Anthracosilicosis (AS), a prevalent form of pneumoconiosis among coal miners, results from the accumulation of carbon and silica in the lungs from inhaled coal dust. This study investigated genotoxic effects and certain cytokine genes polymorphic variants in Russian coal miners with АS. Peripheral leukocytes were sampled from 129 patients with AS confirmed by X-ray and tissue biopsy and from 164 asymptomatic coal miners. Four single-nucleotide polymorphisms were genotyped in the extracted DNA samples: IL1β T-511C (rs16944), IL6 C-174G (rs1800795), IL12b A1188C (rs3212227) and VEGFA C634G (rs2010963). Genotoxic effects were assessed by the analysis of chromosome aberrations in cultured peripheral lymphocytes. The mean frequency of chromatid-type aberrations and chromosome-type aberrations, namely, chromatid-type breaks and dicentric chromosomes, was found to be higher in AS patients [3.70 (95% confidence interval {CI}, 3.29-4.10) and 0.28 (95% CI, 0.17-0.38)] compared to the control group [2.41 (95% CI, 2.00-2.82) and 0.09 (95% CI, 0.03-0.15)], respectively. IL1β gene T/T genotype (rs16944) was associated with AS [17.83% in AS patients against 4.35% in healthy donors, odds ratio = 4.77 (1.88-12.15), P < 0.01]. A significant increase in the level of certain chromosome interchanges among AS donors is of interest because such effects are typical for radiation damage and caused by acute oxidative stress. IL1β T allele probably may be considered as an AS susceptibility factor among coal miners.

ANALISIS PENGARUH THE BIG FIVE PERSONALITY TERHADAP ORGANIZATIONAL CITIZENSHIP BEHAVIOR (OCB DAN KINERJA PERAWAT DI RS SANTA CLARA MADIUN

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Desi Natalia Soepono

2017-04-01

Full Text Available Nurse performance shows the magnitude of the contribution made by nurses to hospital and reflects the performance of a hospital because patient will often relates and meets the nurse. One factor that affect the nurses performance is organizational citizenship behavior (OCB. OCB is extra-role behavior that nurses are willing to do tasks outside of their job discription and the big five personality is one of the factors that significantly influence the OCB. This study aims to examine the direct and indirect influence of the big five personality to the performance of nurses at Santa Clara Madiun Hospital through OCB as intervening variable. The sampel of this research were all nurses at Santa Clara Madiun Hospital. Data collection instruments using questionnaires. Data analysis techniques in this study included descriptive statistics, test data quality, classical assumption, hierarchical regression analysis, and path analysis using SPSS 17.0. The result showed that the big five personality significant positive effect on nurses performance, the big five personality significant positive effect on OCB, and OCB significant positive effect on the nurses performance. OCB has a full mediation effect to influence of the big five personality to the nurses performance

Thin and reliable connectivity for the CBM-MVD

Energy Technology Data Exchange (ETDEWEB)

Klaus, Philipp [Institut fuer Kernphysik, Goethe-Universitaet Frankfurt (Germany); Collaboration: CBM-MVD-Collaboration

2016-07-01

The CBM Micro Vertex Detector requires reliable connectivity to its ∝ 300 CMOS Monolithic Pixel Sensors (CPS). This includes stable powering but also reliable data transmission and fault tolerance. Another requirement is to keep the material budget to a minimum as the cables will be partially in the acceptance of the micro vertex detector. This contribution will summarize our current efforts to reduce the material budget of the readout cables while ensuring reliable connectivity. Our latest prototype of the second station of the MVD (named PRESTO) was studied to obtain the presented results.

The Development of CBM Vocabulary Measures: Grade 5. Technical Report #1212

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 7. Technical Report #1214

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 6. Technical Report # 1213

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 3. Technical Report #1210

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 4. Technical Report #1211

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 8. Technical Report #1215

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 2. Technical Report #1209

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

Avaliação da frequência de incontinência urinária em jogadoras de voleibol amadoras de Santa Maria-RS

Directory of Open Access Journals (Sweden)

Letícia Fernandez Frigo

2015-10-01

Full Text Available As mulheres estão praticando voleibol com vistas a um corpo saudável e buscando melhorar a qualidade de vida e bem estar físico, porém, se não orientadas corretamente, podem desenvolver fraquezas e disfunções pélvicas. Objetivo: este estudo teve como objetivo avaliar a frequência de incontinência urinária em jogadoras amadoras de voleibol de Santa Maria, RS. Método: a amostra foi composta por 23 mulheres praticantes de voleibol, com faixa etária de 23 a 42 anos. Foram realizados encontros em horários previamente agendados com as voluntárias, sendo aplicados os instrumentos de avaliação, a ficha de identificação e o questionário utilizado, a fim de avaliar os sintomas das perdas urinárias e sua história ginecológica. Resultados: sete apresentaram queixa de incontinência urinária; duas relataram perder urina com riso, quatro com tosse, duas com espirro e uma com agachamento, sendo que nove perdem urina em gotas. Das 23 jogadoras cinco apresentam incontinência urinaria leve e quatro moderada. Quanto ao tempo dos sintomas, duas relatam ser há mais de 20 anos, duas há menos de um ano e cinco há seis meses. Considerações finais: os resultados nos mostram fortes indícios para levantar a hipótese de que a Incontinência Urinária em jogadoras de voleibol está relacionada com a atividade e o treinamento de alto impacto, tornando importante a prevenção de tais disfunções para que as atletas não venham a desenvolver patologias no futuro.

Quality assurance of the silicon microstrip sensors for the CBM experiment

Energy Technology Data Exchange (ETDEWEB)

Panasenko, Iaroslav [Physikalisches Institut, Universitaet Tuebingen (Germany); Institute for Nuclear Research, Kiev (Ukraine); Larionov, Pavel [University of Frankfurt (Germany); Collaboration: CBM-Collaboration

2016-07-01

The CBM experiment at FAIR will investigate the properties of nuclear matter at extreme conditions created in ultrarelativistic heavy-ion collisions. Its core detector - the Silicon Tracking System (STS) - will determine the momentum of charged particles from beam-target interactions. The track multiplicity will reach up to 700 within the detector aperture covering the polar angle 2.5 and 25 . High track density as well as stringent requirements to the momentum resolution (∝1%) require a system with high channel granularity and low material budget. The STS will be constructed of about 1200 double-sided silicon microstrip sensors with 58 μm pitch and a total area of ∝4 m{sup 2} with all together 2.1 million channels will be read out. In this talk the quality assurance of double-sided silicon microstrip sensors is discussed. This includes both visual and electrical characterization. For this purpose dedicated equipment has been set up in the clean rooms of the GSI Detector Laboratory and at Tuebingen University. Results of the electrical characterization of prototype microstrip sensors CBM06 are presented.

An improved detector response simulation for the CBM silicon tracking system

Energy Technology Data Exchange (ETDEWEB)

Malygina, Hanna [Goethe University, Frankfurt (Germany); Friese, Volker [GSI, Darmstadt (Germany); Collaboration: CBM-Collaboration

2015-07-01

The Compressed Baryonic Matter experiment(CBM) at FAIR is designed to explore the QCD phase diagram in the region of high net-baryon densities. The central detector component the Silicon Tracking System (STS) is build from double-sided micro-strip sensors. To achieve realistic simulations the response of the silicon strip sensors should be precisely included in the digitizer which simulates a complete chain of physical processes caused by charged particles traversing the detector, from charge creation in silicon to a digital output signal. The new version of the STS digitizer comprises in addition non-uniform energy loss distributions (according to the Urban theory), thermal diffusion and charge redistribution over the read-out channels due to interstrip capacitances. The improved response simulation was tested with parameters reproducing the anticipated running conditions of the CBM experiment. Two different method for cluster finding were used. The results for hit position residuals, cluster size distribution, as well as for some other parameters of reconstruction quality are presented. The achieved advance is assessed by a comparison with the previous, simpler version of the STS detector response simulation.

Performance of centrality determination in heavy-ion collisions with CBM experiment

Energy Technology Data Exchange (ETDEWEB)

Klochkov, Viktor; Selyuzhenkov, Ilya [GSI, Darmstadt (Germany); Collaboration: CBM-Collaboration

2016-07-01

The goal of the CBM experiment at FAIR is to investigate the properties of compressed baryonic matter. The measurement of physics observables in heavy-ion collisions requires information about event geometry. A magnitude of the impact parameter, which is among the most important parameters to describe collision geometry, cannot be measured directly in experiment. One can estimate it by measuring produced particle's multiplicities or energy of the spectator fragments. Typically, the collisions are divided into centrality classes which corresponds to the ranges of impact parameter with e.g. centrality class 0-5% corresponds to most central events, and 95-100% to the most peripheral collisions. Sensitivity to the range of impact parameters with the Silicon Tracking System (STS) and Projectile Spectator Detector (PSD) to select centrality classes in the CBM experiment will be presented. The STS is measuring the multiplicity of the particles produced in the nuclei overlap zone and different areas of the PSD are sensitive to both spectator fragments and produced particles. Supported by the GSI Helmholtzzentrum fuer Schwerionenforschung.

In-beam test of the RPC architecture foreseen to be used for the CBM-TOF inner wall

Science.gov (United States)

Petriş, M.; Bartoş, D.; Petrovici, M.; Rădulescu, L.; Simion, V.; Deppner, I.; Herrmann, N.; Simon, C.; Frühauf, J.; Kiš, M.; Loizeau, P.-A.

2018-05-01

The Time Of Flight (TOF) subsystem is one of the main detectors of the CBM experiment. The TOF wall in conjunction with Silicon Tracking System (STS) is foreseen to identify charged hadrons, i.e. pions, kaons and protons, with a full azimuthal coverage at 2.50 - 250 polar angles. A system time resolution of at least 80 ps, including all contributions, such as electronics jitter and the resolution of the time reference system, is required. Such a performance should be maintained up to a counting rate larger than 30 kHz/cm2 at the most inner region of TOF wall. Our R&D activity has been focused on the development of two-dimensional position sensitive Multi-gap Resistive Plate Counter (MRPC) prototypes for the forward region of the CBM-TOF subdetector, the most demanding zone in terms of granularity and counting rate. The in-beam tests using secondary particles produced in 30 GeV/u Pb ion collisions on a Pb target at SPS - CERN aimed to test the performance of these prototypes in conditions similar to the ones expected at SIS100 at FAIR. The performance of the prototypes is studied in conditions of exposure of the whole active area of the chamber to high multiplicity of reaction products. The results show that this type of MRPC fulfill the challenging requirements of the CBM-TOF wall. Therefore, such an architecture is recommended as basic solution for CBM-TOF inner zone.

Development of a silicon tracking and vertex detection system for the CBM experiment at FAIR

International Nuclear Information System (INIS)

Heuser, Johann M.

2007-01-01

The compressed baryonic matter (CBM) experiment is a fixed-target heavy-ion spectrometer planned at the future international Facility for Antiproton and Ion Research (FAIR) at GSI. The CBM research program will explore the phase diagram of Quantum Chromo Dynamics (QCD) in the region of high baryon chemical potentials, in other words nuclear matter at extreme densities. Matter of such forms is believed to exist in the interior of neutron stars and in the cores of certain types of supernovae. In the laboratory, the dense nuclear medium is created in collisions of heavy-ion beams with nuclear targets. With beam intensities of up to 10 12 ions per pulse, beam energies up to 45 GeV/nucleon, and high availability the SIS-300 synchrotron of FAIR will offer unique opportunities for this research. The CBM detector will identify hadrons and leptons in nuclear collisions with up to 1000 charged particles at event rates up to 10 MHz. The experiment will be optimized in particular for the detection of rare probes, like hadronic decays of D mesons and leptonic decays of light vector mesons, that can yield information on the initial dense phase of the collisions. The challenge is to accomplish in this environment high-resolution charged particle tracking, momentum measurement and secondary vertex selection with a silicon tracking and vertex detection system, the central component of the CBM detector. The system requirements include a very low material budget, radiation tolerant sensors with high spatial resolution, and a fast readout compatible with high-level-only triggers. The paper discusses the concept of the silicon detection system, the optimization of its layout, and the R and D on micro-strip and pixel sensors as well as front-end electronics for the building blocks of the detector stations

Effects of climate change and population growth on the transboundary Santa Cruz aquifer

Science.gov (United States)

Scott, Christopher A.; Megdal, Sharon; Oroz, Lucas Antonio; Callegary, James; Vandervoet, Prescott

2012-01-01

The USA and Mexico have initiated comprehensive assessment of 4 of the 18 aquifers underlying their 3000 km border. Binational management of groundwater is not currently proposed. University and agency researchers plus USA and Mexican federal, state, and local agency staff have collaboratively identified key challenges facing the Santa Cruz River Valley Aquifer located between the states of Arizona and Sonora. The aquifer is subject to recharge variability, which is compounded by climate change, and is experiencing growing urban demand for groundwater. In this paper, we briefly review past, current, and projected pressures on Santa Cruz groundwater. We undertake first-order approximation of the relative magnitude of climate change and human demand drivers on the Santa Cruz water balance. Global circulation model output for emissions scenarios A1B, B1, and A2 present mixed trends, with annual precipitation projected to vary by ±20% over the 21st century. Results of our analysis indicate that urban water use will experience greater percentage change than climate-induced recharge (which remains the largest single component of the water balance). In the Mexican portion of the Santa Cruz, up to half of future total water demand will need to be met from non-aquifer sources. In the absence of water importation and with agricultural water use and rights increasingly appropriated for urban demand, wastewater is increasingly seen as a resource to meet urban demand. We consider decision making on both sides of the border and conclude by identifying short- and longer-term opportunities for further binational collaboration on transboundary aquifer assessment.

Toxicological potential of metals found in soil of cemeteries in Santa Maria - RS

Directory of Open Access Journals (Sweden)

Bruno Casanova Vilaverde Gomes

2016-03-01

Full Text Available Contamination with toxic elements and cemetery leachate may result when proper geo-environmental and hydro geographic studies are not conducted and cemeteries are dug in soils without appropriate structure and chemical properties. This contamination may percolate through the water table, leading to groundwater contamination, which can dramatically affect natural resources and public health. The toxicity of soil from Santa Maria was evaluated in this context. In addition, concentrations of Al, Ca, Cd, Cr, Cu, Fe, Mg, Ni, Pb and Zn were determined and compared with the tolerance limits established by the National Environmental Council Resolution No. 420 of 2013. Oligochaetas of the Eisenia andrei species were used as bio indicators in the format bioassays-limit test (control versus treatment, in a completely randomized design with three replications, consisting of seven treatments and two levels. At the end of the exposure period, we evaluated the effects of acute toxicity in oligochaetas, considering the median lethal concentration (LC50. The results of acute and chronic toxicity studies in the two analyzed cemeteries (urban and rural showed toxicity (CL50 239,88 mg k-1 e 52,48 mg kg-1 and interference in the reproductive process of oligochaetas. We detected concentrations of toxic metals that exceeded legally established values.

Percepção de professoras de ensino médio e fundamental sobre a homofobia na escola em Santa Maria (Rio Grande do Sul/Brasil Elementary and High School teachers'perception on homophobia at school in Santa Maria (Rio Grande do Sul/Brazil

Directory of Open Access Journals (Sweden)

Zulmira Newlands Borges

2011-04-01

Full Text Available Em pesquisa com escolas estaduais na cidade de Santa Maria (RS, em que entrevistamos 20 professoras, observou-se que não existe a preocupação formal com questões de sexualidade na escola. Discriminações e brincadeiras em torno dos que são ou parecem ser homossexuais são geralmente ignoradas. Professoras entrevistadas relatam grandes dificuldades em tratar o tema homofobia em sala de aula. Os dados indicam que é necessário um trabalho educativo com diretoras de escolas e com orientadoras pedagógicas para que estas sejam sensibilizadas para a questão e possam dar suporte para as professoras que tomam para si a tarefa de abordar temas como a homofobia.In research on state schools in the city of Santa Maria (RS, in which 20 teachers were interviewed, it was observed that there is no formal concern with sexuality issues at school. Discrimination and jokes around those who are or appear to be homosexuals are generally ignored. Teachers interviewed reported great difficulty in dealing with the issue homophobia in the classroom. The data indicated that educational work with school principals and mentors is necessary so that they can be sensitized to the issue and can provide support for teachers who take upon themselves the task of addressing issues such as homophobia.

Association of Single Nucleotide Polymorphisms in the ST3GAL4 Gene with VWF Antigen and Factor VIII Activity.

Science.gov (United States)

Song, Jaewoo; Xue, Cheng; Preisser, John S; Cramer, Drake W; Houck, Katie L; Liu, Guo; Folsom, Aaron R; Couper, David; Yu, Fuli; Dong, Jing-Fei

2016-01-01

VWF is extensively glycosylated with biantennary core fucosylated glycans. Most N-linked and O-linked glycans on VWF are sialylated. FVIII is also glycosylated, with a glycan structure similar to that of VWF. ST3GAL sialyltransferases catalyze the transfer of sialic acids in the α2,3 linkage to termini of N- and O-glycans. This sialic acid modification is critical for VWF synthesis and activity. We analyzed genetic and phenotypic data from the Atherosclerosis Risk in Communities (ARIC) study for the association of single nucleotide polymorphisms (SNPs) in the ST3GAL4 gene with plasma VWF levels and FVIII activity in 12,117 subjects. We also analyzed ST3GAL4 SNPs found in 2,535 subjects of 26 ethnicities from the 1000 Genomes (1000G) project for ethnic diversity, SNP imputation, and ST3GAL4 haplotypes. We identified 14 and 1,714 ST3GAL4 variants in the ARIC GWAS and 1000G databases respectively, with 46% being ethnically diverse in their allele frequencies. Among the 14 ST3GAL4 SNPs found in ARIC GWAS, the intronic rs2186717, rs7928391, and rs11220465 were associated with VWF levels and with FVIII activity after adjustment for age, BMI, hypertension, diabetes, ever-smoking status, and ABO. This study illustrates the power of next-generation sequencing in the discovery of new genetic variants and a significant ethnic diversity in the ST3GAL4 gene. We discuss potential mechanisms through which these intronic SNPs regulate ST3GAL4 biosynthesis and the activity that affects VWF and FVIII.

Association analysis of APOA5 rs662799 and rs3135506 polymorphisms with obesity in Moroccan patients.

Science.gov (United States)

Lakbakbi El Yaagoubi, F; Charoute, H; Bakhchane, A; Ajjemami, M; Benrahma, H; Errouagui, A; Kandil, M; Rouba, H; Barakat, A

2015-12-01

The aim of the present study is to explore the association between the APOA5 polymorphisms and haplotypes with obesity in Moroccan patients. The study was performed in 459 subjects, Obese (n=164) and non-obese (n=295). All subjects were genotyped for the APOA5 -1131T>C (rs662799) and c.56C>G (rs3135506) polymorphisms. The contribution of APOA5 polymorphisms and haplotypes in the increased risk of obesity were explored using logistic regression analyses. The -1131T>C and c.56C>G polymorphisms were significantly associated with obesity. Both polymorphisms were strongly associated with increased BMI. Analysis of constructed haplotypes showed a significant association between CG haplotype and susceptibility to obesity (OR [95%CI]=3.09 [1.93-4.97]; P<0.001). These results support a potential role for APOA5 common variants and related haplotypes as risk factors for obesity. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Optimisation of selection cuts for MUCH detector of CBM experiment

International Nuclear Information System (INIS)

Farooq, M.; Ahmad, S.; Chattopadhyay, S.

2015-01-01

The Compressed Baryonic Matter (CBM) experiment is one of the future research program scheduled at FAIR, Darmstadt Germany. The aim of the planned experiment is to explore the Quantum Chromodynamics (QCD) phase diagram in the regions of high baryonic densities and moderate temperatures in the beam energy range of 10-45 AGeV. This approach is complementary to the studies of matter at high temperatures and low net baryon densities performed at RHIC and LHC. CBM will also search for the critical point, the first order deconfinement phase transition from the hadronic matter to the partonic matter and the study of equation-of-state of dense baryonic matter. Comprehensive scan of observables, beam energies and collision systems is realised. The observables include: low mass dilepton pairs, charmonia and open charm, collective flow of rare and bulk particles, correlations and fluctuations etc. Low yield measurements of rare probes, like charmonium and low mass vector mesons, have to be performed at very high reaction rates ∼10 MHz. These conditions demand for fast and radiation hard detectors and associated fast electronics, readout and online event reconstruction. Low material budget is required with in the detector acceptance to avoid multiple scattering which would limit high precision measurements

Studies on high performance Timeslice building on the CBM FLES

Energy Technology Data Exchange (ETDEWEB)

Hartmann, Helvi [Frankfurt Institute for Advanced Studies, Goethe University, Frankfurt (Germany); Collaboration: CBM-Collaboration

2015-07-01

In contrast to already existing high energy physics experiments the Compressed Baryonic Matter (CBM) experiment collects all data untriggered. The First-level Event Selector (FLES), which denotes a high performance computer cluster, processes the very high incoming data rate of 1 TByte/s and performs a full online event reconstruction. For this task it needs to access the raw detector data in time intervals referred to as Timeslices. In order to construct the Timeslices, the FLES Timeslice building has to combine data from all input links and distribute them via a high-performance network to the compute nodes. For fast data transfer the Infiniband network has proven to be appropriate. One option to address the network is using Infiniband (RDMA) Verbs directly and potentially making best use of Infiniband. However, it is a very low-level implementation relying on the hardware and neglecting other possible network technologies in the future. Another approach is to apply a high-level API like MPI which is independent of the underlying hardware and suitable for less error prone software development. I present the given possibilities and show the results of benchmarks ran on high-performance computing clusters. The solutions are evaluated regarding the Timeslice building in CBM.

Highly parallel algorithm for high pT physics at FAIR-CBM

International Nuclear Information System (INIS)

Fueloep, A; Vesztergombi, G

2010-01-01

The limitations of presently available data on p T range are discussed and planned future upgrades are outlined. Special attention is given to the FAIR-CBM experiment as a unique high luminosity facility for future continuation of the measurements at very high p T with emphasis on the so-called mosaic trigger system to use the highly parallel online algorithm.

A espacialização da violência criminal na cidade de Santa Maria, RS La spatialisation des crimes et delits dans la ville de Santa Maria, RS The distribution of criminal violence in the city of Santa Maria, RS

Directory of Open Access Journals (Sweden)

Eliane Melara

2012-03-01

Full Text Available Violência e criminalidade são temáticas abrangentes e, de acordo com a abordagem utilizada, podem ser explicadas sob diferentes vieses. Neste trabalho foi priorizado o que se denominou de violência criminal, com enfoque no mapeamento de informações. Nosso intuitofoiproblematizar a espacialização diferenciada das ocorrências criminais no espaço urbano de uma cidade média no sul do Brasil - Santa Maria, focando como os diferentes tipos de crimes estão distribuídos pelos bairros da cidade, considerando características socioeconômicas nesta análise. Metodologicamente, utilizamos o mapeamento dos dados fornecidos pelo IBGE e aqueles provenientes das ocorrências criminais obtidos junto à brigada militar do estado do Rio Grande do Sul. Fizemos uso também de relatos de diversos atores da cidade, uma vez que seus posicionamentos foram importantes para ajudar a entender a dinâmica da violência criminal na cidade. Nossos resultados apontam que as ocorrências criminais relacionadas ao tráfico de drogas concentram-se numa área onde os níveis de renda e instrução são baixos, porém muitos traficantes e consumidores são residentes de outras partes da cidade e caracterizados por pertencer a diferentes classes sociais, embora essas informações não apareçam com frequência nas estatísticas. Além disso, observamos que, a partir desse tipo de crime, ocorrem outros, como: roubos, furtos e agressões. Verificamos também que os crimes contra a pessoa, de modo geral, distribuem-se diferentemente dos crimes contra o patrimônio, e que em muitos casos essa diferenciação pode estar relacionada a fatores sociais, econômicos e de infraestutura urbana do bairro. É importante acrescentar que a ocorrência de alguns tipos de crimes seguiu padrões específicos. Assim, nesse estudo, foi preciso questionar as fontes de dados pesquisadas, o porquê da ocorrência diferenciada dos crimes nos bairros, possíveis vítimas e agressores, por que

Dos trilhos aos palacetes: refletindo sobre o acervo arquitetônico da Av. Rio Branco, Santa Maria, RS

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Maria Dinair Machado

2015-12-01

Full Text Available Este artigo propõe uma análise sobre a preservação e conservação do patrimônio cultural edificado no centro do município de Santa Maria, mais precisamente o patrimônio localizado na Avenida Rio Branco, na área central da cidade. O município possui sua história vinculada à ferrovia que se pode observar no patrimônio cultural edificado,  sua riqueza e diversidade, localizado no centro urbano. O nosso recorte espacial é focado na antiga Avenida Progresso, atual Avenida Rio Branco, eixo que ligava a estação férrea a Praça Saldanha Marinho e a Rua do Acampamento na área central. Para este trabalho foi  realizada  pesquisa  exploratória qualitativa, utilizando-se de observação por meio de registros fotográficos do centro histórico de Santa Maria, delimitando-se à  Avenida Rio Branco. No trabalho consta um breve histórico desta avenida, uma descrição dos prédios de valor histórico e as ações realizadas ao longo dos últimos anos. Nas conclusões, é proposta uma possibilidade de intervenção territorial a partir das necessidades como políticas públicas de preservação decorrentes do atual estado de abandono das edificações naquele local.

Genetic association of polymorphism rs1333049 with gout.

Science.gov (United States)

Wang, Binbin; Meng, Dongmei; Wang, Jing; Liu, Shiguo; Zhou, Sirui; Miao, Zhimin; Han, Lin; Chu, Nan; Zhang, Kun; Ma, Xu; Li, Changgui

2011-09-01

We suspect that genes or loci that contribute to coronary artery disease (CAD) may also play a role in the pathogenesis of gout, since hyperuricaemia leads to gout, and serum uric acid (SUA) levels are potential risk factors for CAD. The single nucleotide polymorphism (SNP) rs1333049 (C/G) on chromosome 9p21 has been implicated in previous studies to be associated with CAD. The aim of this study was to evaluate the relationship between this SNP and gout pathogenesis. Nine hundred Chinese Han were recruited for this study (461 gout patients and 439 gout-free individuals). The rs1333049 SNP and surrounding sequences were PCR sequenced. There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls (χ(2) = 6.81, df = 2, P = 0.033 by genotype; χ(2) = 6.63, df = 1, P = 0.01 by allele). There was a significantly increased risk of gout in carriers of the CC genotype (odds ratio = 1.43, 95% CI 1.07, 1.91). To the best of our knowledge, our findings are the first to establish an association of rs1333049 with gout in a Chinese Han population. Meanwhile, this SNP is homologous to miR-519 and miR-520.

Hadron azimuthal correlations to be studied at CBM setup

International Nuclear Information System (INIS)

Pozdnyakov, V.; Vertogradova, Yu.

2008-01-01

An opportunity of studying hadron azimuthal correlations with the CBM detector (GSI, Germany) is considered. The results include the full simulation of the UrQMD events together with a simplified consideration of the calorimeter near the beam-pipe. The expectations of the correlations are presented. The centrality determination is considered via both the charged particles detected in the tracking system and the energy deposited in the calorimeter. The segmentation of the calorimeter is discussed from the point of view of the determination accuracy of the reaction plane

Frequency of suspected cases of neurocysticercosis detected by computed skull tomography in Santa Maria, Rio Grande do Sul State, Brazil

International Nuclear Information System (INIS)

Silva, Jose Edson Paz da

2000-01-01

Due to the lack of studies about neurocysticercosis in the South of Brazil, an investigation was conducted to determine the percentage cases of neurocysticercosis in computed tomography diagnoses in Santa Maria, RS, from January 1997 to December 1998. Of 6300 computed tomographs (CT) of the skull performed at the private Hospital de Caridade Astrogildo de Azevedo, 80, i.e. 1.27% were suspected of neurocysticercosis. Fifty were women (62.5%) and 30 were men (37.5). The most frequent radiological manifestation indicating neurocysticercosis was the presence of calcifications (isolated or associated), with a 95% rate (76 cases), while the presence of hypodense lesions reached a 5% rate (4 cases). After routine analysis, each CT was evaluated again and the suspected cases were confirmed. The percentage of suspected cases of neurocysticercosis detected by CT in the present study carried out in santa Maria was considered low (1.27%). This can be explained by the fact that tomography is not accessible to the economically underprivileged population of Santa Maria. We hope that the present study can alert the population and the professionals to the fact neurocysticercosis is a more frequent disease than indicated by the few diagnoses made. (author)

Frequency of suspected cases of neurocysticercosis detected by computed skull tomography in Santa Maria, Rio Grande do Sul State, Brazil

Energy Technology Data Exchange (ETDEWEB)

Silva, Jose Edson Paz da [Santa Maria Univ., RS (Brazil). Dept. de Analises Clinicas e Toxicologicas; Diefenthaeler, Ana Paula [Santa Maria Univ., RS (Brazil). Curso de Farmacia e Bioquimica; Palma, Jose Knoll [Hospital de Caridade Astrogildo de Azevedo, Santa Maria, RS (Brazil)

2000-02-01

Due to the lack of studies about neurocysticercosis in the South of Brazil, an investigation was conducted to determine the percentage cases of neurocysticercosis in computed tomography diagnoses in Santa Maria, RS, from January 1997 to December 1998. Of 6300 computed tomographs (CT) of the skull performed at the private Hospital de Caridade Astrogildo de Azevedo, 80, i.e. 1.27% were suspected of neurocysticercosis. Fifty were women (62.5%) and 30 were men (37.5). The most frequent radiological manifestation indicating neurocysticercosis was the presence of calcifications (isolated or associated), with a 95% rate (76 cases), while the presence of hypodense lesions reached a 5% rate (4 cases). After routine analysis, each CT was evaluated again and the suspected cases were confirmed. The percentage of suspected cases of neurocysticercosis detected by CT in the present study carried out in santa Maria was considered low (1.27%). This can be explained by the fact that tomography is not accessible to the economically underprivileged population of Santa Maria. We hope that the present study can alert the population and the professionals to the fact neurocysticercosis is a more frequent disease than indicated by the few diagnoses made. (author)

Association between vitamin D concentration and levels of sex hormones in an elderly Polish population with different genotypes of VDR polymorphisms (rs10735810, rs1544410, rs7975232, rs731236).

Science.gov (United States)

Laczmanski, Lukasz; Lwow, Felicja; Mossakowska, Malgorzata; Puzianowska-Kuznicka, Monika; Szwed, Małgorzata; Kolackov, Katarzyna; Krzyzanowska-Swiniarska, Barbara; Bar-Andziak, Ewa; Chudek, Jerzy; Sloka, Natalia; Milewicz, Andrzej

2015-03-15

Vitamin D co-regulates the synthesis of sex hormones in part by interaction with its nuclear receptor. The aim of this study was to determine whether there is an association of vitamin D concentration vs the level of sex hormones in elderly Polish individuals with different genotypes of the vitamin D receptor (VDR) gene. Rs10735810, rs1544410, rs7975232, and rs731236 polymorphisms of VDR, the serum sex hormone level, free estrogen index (FEI) and free androgen index (FAI) as well as vitamin D, were evaluated in 766 persons (362 women and 404 men) selected from 5695 Polish population, aged 65-90years from the PolSenior survey. We observed that women with GG (rs731236), TT (rs7975232), BB (rs1544410) and FF (rs10735810) genotypes were characterized by a significant correlation between vitamin D vs testosterone concentration and FAI value. We found a significant correlation between testosterone level and FAI vs vitamin D concentration in men with heterozygote AG in the rs731236 polymorphism and in the GG (rs7975232), the BB (rs1544410), and the Ff (rs10735810) genotypes. In elderly selected Polish population with different genotypes of VDR polymorphisms, a statistically significant relationship between vitamin D concentration vs testosterone level was observed. Copyright © 2015 Elsevier B.V. All rights reserved.

Santa and the Moon

NARCIS (Netherlands)

Barthel, P.

This article reflects on the use of illustrations of the Moon in images of Santa Claus, on Christmas gift-wrapping paper and in children's books, in two countries which have been important in shaping the image of Santa Claus and his predecessor Sinterklaas: the USA and the Netherlands. The

Growth modulation effects of CBM2a under the control of AtEXP4 and CaMV35S promoters in Arabidopsis thaliana, Nicotiana tabacum and Eucalyptus camaldulensis.

Science.gov (United States)

Keadtidumrongkul, Pornthep; Suttangkakul, Anongpat; Pinmanee, Phitsanu; Pattana, Kanokwan; Kittiwongwattana, Chokchai; Apisitwanich, Somsak; Vuttipongchaikij, Supachai

2017-08-01

The expression of cell-wall-targeted Carbohydrate Binding Modules (CBMs) can alter cell wall properties and modulate growth and development in plants such as tobacco and potato. CBM2a identified in xylanase 10A from Cellulomonas fimi is of particular interest for its ability to bind crystalline cellulose. However, its potential for promoting plant growth has not been explored. In this work, we tested the ability of CBM2a to promote growth when expressed using both CaMV35S and a vascular tissue-specific promoter derived from Arabidopsis expansin4 (AtEXP4) in three plant species: Arabidopsis, Nicotiana tabacum and Eucalyptus camaldulensis. In Arabidopsis, the expression of AtEXP4pro:CBM2a showed trends for growth promoting effects including the increase of root and hypocotyl lengths and the enlargements of the vascular xylem area, fiber cells and vessel cells. However, in N. tabacum, the expression of CBM2a under the control of either CaMV35S or AtEXP4 promoter resulted in subtle changes in the plant growth, and the thickness of secondary xylem and vessel and fiber cell sizes were generally reduced in the transgenic lines with AtEXP4pro:CBM2a. In Eucalyptus, while transgenics expressing CaMV35S:CBM2a showed very subtle changes compared to wild type, those transgenics with AtEXP4pro:CBM2a showed increases in plant height, enlargement of xylem areas and xylem fiber and vessel cells. These data provide comparative effects of expressing CBM2a protein in different plant species, and this finding can be applied for plant biomass improvement.

Predicting Hip Fracture Type With Cortical Bone Mapping (CBM) in the Osteoporotic Fractures in Men (MrOS) Study.

Science.gov (United States)

Treece, Graham M; Gee, Andrew H; Tonkin, Carol; Ewing, Susan K; Cawthon, Peggy M; Black, Dennis M; Poole, Kenneth E S

2015-11-01

Hip fracture risk is known to be related to material properties of the proximal femur, but fracture prediction studies adding richer quantitative computed tomography (QCT) measures to dual-energy X-ray (DXA)-based methods have shown limited improvement. Fracture types have distinct relationships to predictors, but few studies have subdivided fracture into types, because this necessitates regional measurements and more fracture cases. This work makes use of cortical bone mapping (CBM) to accurately assess, with no prior anatomical presumptions, the distribution of properties related to fracture type. CBM uses QCT data to measure the cortical and trabecular properties, accurate even for thin cortices below the imaging resolution. The Osteoporotic Fractures in Men (MrOS) study is a predictive case-cohort study of men over 65 years old: we analyze 99 fracture cases (44 trochanteric and 55 femoral neck) compared to a cohort of 308, randomly selected from 5994. To our knowledge, this is the largest QCT-based predictive hip fracture study to date, and the first to incorporate CBM analysis into fracture prediction. We show that both cortical mass surface density and endocortical trabecular BMD are significantly different in fracture cases versus cohort, in regions appropriate to fracture type. We incorporate these regions into predictive models using Cox proportional hazards regression to estimate hazard ratios, and logistic regression to estimate area under the receiver operating characteristic curve (AUC). Adding CBM to DXA-based BMD leads to a small but significant (p fracture, with AUC increasing from 0.78 to 0.79, assessed using leave-one-out cross-validation. For specific fracture types, the improvement is more significant (p trochanteric fractures and 0.76 to 0.82 for femoral neck fractures. In contrast, adding DXA-based BMD to a CBM-based predictive model does not result in any significant improvement. © 2015 The Authors. Journal of Bone and Mineral Research

Technical Adequacy of the easyCBM Grade 2 Reading Measures. Technical Report #1004

Science.gov (United States)

Jamgochian, Elisa; Park, Bitnara Jasmine; Nese, Joseph F. T.; Lai, Cheng-Fei; Saez, Leilani; Anderson, Daniel; Alonzo, Julie; Tindal, Gerald

2010-01-01

In this technical report, we provide reliability and validity evidence for the easyCBM[R] Reading measures for grade 2 (word and passage reading fluency and multiple choice reading comprehension). Evidence for reliability includes internal consistency and item invariance. Evidence for validity includes concurrent, predictive, and construct…

Mechanical integration of the detector components for the CBM silicon tracking system

Energy Technology Data Exchange (ETDEWEB)

Vasylyev, Oleg; Niebur, Wolfgang [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Collaboration: CBM-Collaboration

2016-07-01

The Compressed Baryonic Matter experiment (CBM) at FAIR is designed to explore the QCD phase diagram in the region of high net-baryon densities. The central detector component, the Silicon Tracking System (STS) is based on double-sided micro-strip sensors. In order to achieve the physics performance, the detector mechanical structures should be developed taking into account the requirements of the CBM experiments: low material budget, high radiation environment, interaction rates, aperture for the silicon tracking, detector segmentation and mounting precision. A functional plan of the STS and its surrounding structural components is being worked out from which the STS system shape is derived and the power and cooling needs, the connector space requirements, life span of components and installation/repair aspects are determined. The mechanical integration is at the point of finalizing the design stage and moving towards production readiness. This contribution shows the current processing state of the following engineering tasks: construction space definition, carbon ladder shape and manufacturability, beam-pipe feedthrough structure, prototype construction, cable routing and modeling of the electronic components.

Development and test of the readout system for the CBM-MVD prototype

Energy Technology Data Exchange (ETDEWEB)

Milanovic, Borislav; Neuman, Bertram; Wiebusch, Michael; Amar-Youcef, Samir; Froehlich, Ingo; Stroth, Joachim [Institut fuer Kernphysik, Goethe-Universitaet Frankfurt, Frankfurt am Main (Germany); Collaboration: CRESST-Collaboration; CBM-MVD Collaboration

2013-07-01

The CBM Experiment at FAIR aims towards better understanding of the QCD phase-diagram and in-medium properties of matter under high densities. In order to enhance the detection of rare probes via their secondary decay vertices and to support the primary tracking system, the CBM Micro Vertex Detector (MVD) is foreseen. Recently, the MVD Prototype has been developed at the IKF in Frankfurt. The module contains one quarter of the first MVD station featuring four prototype-sensors MIMOSA-26 AHR thinned down to 50 μ m. The prototype has been tested at the CERN SPS accelerator with high energetic pions in November 2012. This contribution discusses the stability and scalability of the DAQ, slow-control and monitoring routines during the beamtime, as well as sensor behavior under high load of up to 700 000 particles per second. The readout system partially uses hardware from the HADES detector which will also run at FAIR. Readout rates of 98 MB/s at the limit of gigabit ethernet have been achieved showing no sign of data loss or corruption.

Interleukin-6-receptor polymorphisms rs12083537, rs2228145, and rs4329505 as predictors of response to tocilizumab in rheumatoid arthritis

DEFF Research Database (Denmark)

Enevold, Christian; Baslund, Bo; Linde, Louise

2014-01-01

Tocilizumab (TCZ), a monoclonal antibody targeting the human interleukin-6-receptor (IL-6R), is indicated for the treatment of rheumatoid arthritis (RA). We examined whether three IL6R single-nucleotide polymorphisms rs12083537, rs2228145 (formerly rs8192284), and rs4329505 with previously report...

Problems in the development of high-rank CBM horizontal wells in the Fanzhuang–Zhengzhuang Block in the Qinshui Basin and countermeasures

Directory of Open Access Journals (Sweden)

Yongping Zhang

2017-11-01

Full Text Available Coal reservoirs in the Qinshui Basin are characterized by high thermal evolution degree, low permeability, low reservoir pressure, lower gas saturation and strong heterogeneity, so its coalbed methane (CBM development is quite difficult. In this paper, the development practice of high-rank CBM horizontal wells in the Fanzhuang–Zhengzhuang Block was analyzed in terms of geological and engineering factors to clarify the productivity influencing factors, suitable geological conditions and potential tapping countermeasures of multi-lateral horizontal wells. It is shown that the reasons for the low development efficiency of multi-lateral horizontal wells are divided into three types. The first one is geological factor, such as encountering low CBM content areas or faults. The second is engineering factor, such as drilling fluid plugging, drilling collapse, drainage collapse and dust coal blockage. The third is the combination of both factors. It is concluded that encountering low CBM content areas and faults, collapse and blockage are the main reasons for the low production of multi-lateral horizontal wells in the Zhengzhuang–Fanzhuang Block, with the CBM content higher than 20 m3/t, the ratio of critical desorption pressure and reservoir pressure higher than 0.7 and vitrinite reflectance (Ro higher than 3.8. The prerequisite for an open-hole horizontal well in this area to produce CBM at a high rate is that the well lies in the tensile stress zone. Finally, the countermeasures to tap the potential of some inefficient wells were put forward. First, the inefficient wells which are blocked with dust coal or collapsed in the later stage should be stimulated based on classifications. And second, it is necessary to explore new types of horizontal wells so as to deal with borehole collapse and continue the operation in the later stage by using tree-like roof horizontal wells, single-lateral horizontal wells with casing or screen completion and fish

Association of ITPA polymorphisms rs6051702/rs1127354 instead of rs7270101/rs1127354 as predictor of ribavirin-associated anemia in chronic hepatitis C treated patients.

Science.gov (United States)

D'Avolio, Antonio; De Nicolò, Amedeo; Cusato, Jessica; Ciancio, Alessia; Boglione, Lucio; Strona, Silvia; Cariti, Giuseppe; Troshina, Giulia; Caviglia, Gian Paolo; Smedile, Antonina; Rizzetto, Mario; Di Perri, Giovanni

2013-10-01

Functional variants rs7270101 and rs1127354 of inosine triphosphatase (ITPA) were recently found to protect against ribavirin (RBV)-induced hemolytic anemia. However, no definitive data are yet available on the role of no functional rs6051702 polymorphism. Since a simultaneous evaluation of the three ITPA SNPs for hemolytic anemia has not yet been investigated, we aimed to understand the contribution of each SNPs and its potential clinical use to predict anemia in HCV treated patients. A retrospective analysis included 379 HCV treated patients. The ITPA variants rs6051702, rs7270101 and rs1127354 were genotyped and tested for association with achieving anemia at week 4. We also investigated, using multivariate logistic regression, the impact of each single and paired associated polymorphism on anemia onset. All SNPs were associated with Hb decrease. The carrier of at least one variant allele in the functional ITPA SNPs was associated with a lower decrement of Hb, as compared to patients without a variant allele. In multivariate logistic regression analyses the carrier of a variant allele in the rs6051702/rs1127354 association (OR=0.11, p=1.75×10(-5)) and Hb at baseline (OR=1.51, p=1.21×10(-4)) were independently associated with protection against clinically significant anemia at week 4. All ITPA polymorphisms considered were shown to be significantly associated with anemia onset. A multivariate regression model based on ITPA genetic polymorphisms was developed for predicting the risk of anemia. Considering the characterization of pre-therapy anemia predictors, rs6051702 SNP in association to rs1127354 is more informative in order to avoid this relevant adverse event. Copyright © 2013 Elsevier B.V. All rights reserved.

Core drilling provides information about Santa Fe Group aquifer system beneath Albuquerque's West Mesa

Science.gov (United States)

Allen, B.D.; Connell, S.D.; Hawley, J.W.; Stone, B.D.

1998-01-01

Core samples from the upper ???1500 ft of the Santa Fe Group in the Albuquerque West Mesa area provide a first-hand look at the sediments and at subsurface stratigraphic relationships in this important part of the basin-fill aquifer system. Two major hydrostratigraphic subunits consisting of a lower coarse-grained, sandy interval and an overlying fine-grained, interbedded silty sand and clay interval lie beneath the water table at the 98th St core hole. Borehole electrical conductivity measurements reproduce major textural changes observed in the recovered cores and support subsurface correlations of hydrostratigraphic units in the Santa Fe Group aquifer system based on geophysical logs. Comparison of electrical logs from the core hole and from nearby city wells reveals laterally consistent lithostratigraphic patterns over much of the metropolitan area west of the Rio Grande that may be used to delineate structural and related stratigraphic features that have a direct bearing on the availability of ground water.

Association of Single Nucleotide Polymorphisms in the ST3GAL4 Gene with VWF Antigen and Factor VIII Activity.

Directory of Open Access Journals (Sweden)

Jaewoo Song

Full Text Available VWF is extensively glycosylated with biantennary core fucosylated glycans. Most N-linked and O-linked glycans on VWF are sialylated. FVIII is also glycosylated, with a glycan structure similar to that of VWF. ST3GAL sialyltransferases catalyze the transfer of sialic acids in the α2,3 linkage to termini of N- and O-glycans. This sialic acid modification is critical for VWF synthesis and activity. We analyzed genetic and phenotypic data from the Atherosclerosis Risk in Communities (ARIC study for the association of single nucleotide polymorphisms (SNPs in the ST3GAL4 gene with plasma VWF levels and FVIII activity in 12,117 subjects. We also analyzed ST3GAL4 SNPs found in 2,535 subjects of 26 ethnicities from the 1000 Genomes (1000G project for ethnic diversity, SNP imputation, and ST3GAL4 haplotypes. We identified 14 and 1,714 ST3GAL4 variants in the ARIC GWAS and 1000G databases respectively, with 46% being ethnically diverse in their allele frequencies. Among the 14 ST3GAL4 SNPs found in ARIC GWAS, the intronic rs2186717, rs7928391, and rs11220465 were associated with VWF levels and with FVIII activity after adjustment for age, BMI, hypertension, diabetes, ever-smoking status, and ABO. This study illustrates the power of next-generation sequencing in the discovery of new genetic variants and a significant ethnic diversity in the ST3GAL4 gene. We discuss potential mechanisms through which these intronic SNPs regulate ST3GAL4 biosynthesis and the activity that affects VWF and FVIII.

The prevalence of psychotherapy and psychopharmacotherapy at the Integrated Health and Social Well Being Center of Santa Maria, state of Rio Grande do Sul (RS - DOI: 10.3395/reciis.v3i4.248en

Directory of Open Access Journals (Sweden)

Cecilia Cassol Dalmolin

2009-12-01

Full Text Available This study aims to verify the prevalence of psychopharmacotherapy and psychotherapy and the therapeutic interaction between these at the Integrated Health and Social Well Being Center (Cisbes located in the town of Santa Maria/RS. For this purpose, a descriptive survey of the therapeutic practices used in the said service during the period from January to July 2005 was carried out, along with a survey of the user profile, using sociodemographic variables. The results show that 1456 people were undergoing treatment during the time of research. Out of these people, 78% (1140 received psychopharmacological treatment, 9% (132 received psychotherapy and 13% (184 had therapeutic interaction. It was seen that the average user age was 36, most were married, 75% lived with family members, 69% were women and 51% had basic schooling. The study looks at factors that may be associated to the results obtained, both in relation to the mental health care model in Brazil and also the possible difficulties faced by the mental health services in the public network.

A first level trigger approach for the CBM experiment

International Nuclear Information System (INIS)

Steinle, Christian Alexander

2012-01-01

In view of the very heavy CBM experiment constraints on the first level trigger, no conventional trigger is obviously applicable. Hence a fast trigger algorithm with the goal of realization in reconfigurable hardware had to be developed to fulfil all requirements of the experiment. In this connection the general Hough transform, which is already utilized in several other experiments, is used as a basis. This approach constitutes further a global method for tracking, which transforms all particle interaction points with the detector stations by means of a defined formula into a parameter space corresponding to the momentum of the particle tracks. This formula is of course developed especially for the given environment of CBM and defines thus the core of the applied three dimensional Hough transform. As the main focus of attention is furthermore on the realization of the needed data throughput, the necessary complex formula calculations give reason to outsource predefined formula results in look-up tables. This circumstance offers then collaterally the possibility to utilize any other sufficiently precise method like Runge-Kutta of fourth order for example to compute these look-up tables, because this computation can be evidently done offline without any effect on the Hough transform's processing speed. For algorithm simulation purposes the CBMROOT framework provides the module 'track', which is written in the programming language C++. This module includes many analyses for the determination of algorithm parameters, which can be even executed automatically to some extent. In addition to this, there are of course also analyses for the measurement of the algorithm's quality as well as for the individual rating of each partial step of the algorithm. Consequently the milestone of a customizable level one tracking algorithm, which can be used without any specific knowledge, is now obtained. Besides this, the investigated concepts are explicitly considered in the

A first level trigger approach for the CBM experiment

Energy Technology Data Exchange (ETDEWEB)

Steinle, Christian Alexander

2012-07-01

In view of the very heavy CBM experiment constraints on the first level trigger, no conventional trigger is obviously applicable. Hence a fast trigger algorithm with the goal of realization in reconfigurable hardware had to be developed to fulfil all requirements of the experiment. In this connection the general Hough transform, which is already utilized in several other experiments, is used as a basis. This approach constitutes further a global method for tracking, which transforms all particle interaction points with the detector stations by means of a defined formula into a parameter space corresponding to the momentum of the particle tracks. This formula is of course developed especially for the given environment of CBM and defines thus the core of the applied three dimensional Hough transform. As the main focus of attention is furthermore on the realization of the needed data throughput, the necessary complex formula calculations give reason to outsource predefined formula results in look-up tables. This circumstance offers then collaterally the possibility to utilize any other sufficiently precise method like Runge-Kutta of fourth order for example to compute these look-up tables, because this computation can be evidently done offline without any effect on the Hough transform's processing speed. For algorithm simulation purposes the CBMROOT framework provides the module 'track', which is written in the programming language C++. This module includes many analyses for the determination of algorithm parameters, which can be even executed automatically to some extent. In addition to this, there are of course also analyses for the measurement of the algorithm's quality as well as for the individual rating of each partial step of the algorithm. Consequently the milestone of a customizable level one tracking algorithm, which can be used without any specific knowledge, is now obtained. Besides this, the investigated concepts are explicitly

A first level trigger approach for the CBM experiment

Energy Technology Data Exchange (ETDEWEB)

Steinle, Christian Alexander

2012-07-01

In view of the very heavy CBM experiment constraints on the first level trigger, no conventional trigger is obviously applicable. Hence a fast trigger algorithm with the goal of realization in reconfigurable hardware had to be developed to fulfil all requirements of the experiment. In this connection the general Hough transform, which is already utilized in several other experiments, is used as a basis. This approach constitutes further a global method for tracking, which transforms all particle interaction points with the detector stations by means of a defined formula into a parameter space corresponding to the momentum of the particle tracks. This formula is of course developed especially for the given environment of CBM and defines thus the core of the applied three dimensional Hough transform. As the main focus of attention is furthermore on the realization of the needed data throughput, the necessary complex formula calculations give reason to outsource predefined formula results in look-up tables. This circumstance offers then collaterally the possibility to utilize any other sufficiently precise method like Runge-Kutta of fourth order for example to compute these look-up tables, because this computation can be evidently done offline without any effect on the Hough transform's processing speed. For algorithm simulation purposes the CBMROOT framework provides the module 'track', which is written in the programming language C++. This module includes many analyses for the determination of algorithm parameters, which can be even executed automatically to some extent. In addition to this, there are of course also analyses for the measurement of the algorithm's quality as well as for the individual rating of each partial step of the algorithm. Consequently the milestone of a customizable level one tracking algorithm, which can be used without any specific knowledge, is now obtained. Besides this, the investigated concepts are explicitly considered in the

Association of IL28B SNPs rs12979860 and rs8099917 on Hepatitis C Virus-RNA Status in Donors/Recipients of Living Donor Liver Transplantation.

Directory of Open Access Journals (Sweden)

King-Wah Chiu

Full Text Available To investigate the effect of IL28B single nucleotide polymorphisms (SNPs (rs8099917 and rs12979860 in the donors and recipients on the outcome of Hepatitis C virus-RNA clearance after living donor liver transplantation (LDLT. The rs8099917 and rs12979860 genotypes in 50 donor and recipients pairs were explored on the pre-operative day (POD and post-operative day 30 (POD30. There was a significant difference in HCV-RNA clearance before (12%, 6/50 and after (48%, 24/50 liver transplantation (P < 0.001. The rs8099917 genotype TT was dominant in both the recipients (82%, 41/50 and donors (86%, 43/50, but had no significant effect on HCV-RNA clearance (87.5%, 21/24 and recurrence (76.9%, 20/26 after LDLT. One recipient was detected with genotype GG on POD, which changed to genotype GT on POD30. Prevalence of rs12979860 genotype CT was 98% (49/50 recipient and 92% (46/50 donor and prevalence of genotype CC was 2% (1/50 recipient and 8% (4/50 donor on POD and POD30, respectively. Of the 4 recipients with rs12979860 genotype CC on POD30, 3 recipients (12.5%, 3/24 exhibited HCV clearance and 1 experienced recurrence (3.9%, 1/26, however, this was not statistically significant. In conclusion, alterations in IL28B SNP genotype may occur after LDLT, leading to modifications in the host genome or donor proteome by HCV. This predicted mechanism will need to be investigated further.

Design of large size segmented GEM foils and Drift PCB for CBM MUCH

International Nuclear Information System (INIS)

Saini, J.; Dubey, A.K.; Chattopadhyay, S.

2016-01-01

Triple GEM (Gas Electron Multiplier), sector shaped detectors will be used for Muon tracking in the Compressed Baryonic Matter (CBM) experiment at Anti-proton Ion Research (FAIR) facility at Darmstadt, Germany. The sizes of the detectors modules in the Muon Chambers (MUCH) are of the order of 1 meter with active area of about 75cms. Progressive pad geometry is chosen for the readout from these detectors. In construction of these chambers, three GEM foils are stacked on top of each other in a 3/2/2/2 gap configuration. The GEM foils are double layered copper clad 50μm thin Kapton foil. Each GEM foil has millions of holes on it. Foils of large surface area are prone to damages due to discharges owing to the high capacitance of the foil. Hence, these foils have their top surfaces divided into segments of about 100 sq.cm. Further segmentation may be necessary when there are high rate requirements, as in the case of CBM. For the GEM foils of CBM MUCH, a 24 segment layout has been adopted. Short-circuit in any of the GEM-holes will make entire foil un-usable. To reduce such occurrences, segment to segment isolation using opto-coupler in series with the GEM-foil segments has been introduced. Hence, a novel design for GEM chamber drift-PCB and foils has been made. In this scheme, each segment is powered and controlled individually. At the same time, the design takes into account, the space constraints, not only in x-y plane, but also in the z, due to compact assembly of MUCH detector layers

Butterflies (Lepidoptera: Papilionoidea and Hesperioidea visiting flowers in the Botanical Garden of the Federal University of Santa Maria, Santa Maria, RS, Brazil

Directory of Open Access Journals (Sweden)

Ana Beatriz Barros de Morais

2008-12-01

Full Text Available Urban environments, such as parks and gardens, may offer many alimentary resources, besides shelter and favorable conditions, for butterfly survival. This study aimed to make an inventory of butterflies visiting flowers in the Botanical Garden of the Federal University of Santa Maria (UFSM. From March 2006 to March 2007, the floral visitors were observed weekly for 2h. After 108 hours’ observations, 1114 visits by 39 butterfly species, associated with 43 plant species (21 families, were confirmed. Among the butterflies, Nymphalidae had the highest richness of species (S= 18, followed by Hesperiidae (S= 8, Pieridae (S= 7, Papilionidae (S= 4 and Lycaenidae (S= 2. The pierid Phoebis philea philea was the most frequent species (188 visits, followed by hesperiids Urbanus proteus proteus (100, U. teleus (73 and the nymphalid Heliconius erato phyllis (71. Lantana camara (Verbenaceae, Eupatorium laevigatum (Asteraceae, Russelia equisetiformis (Scrophulariaceae and Stachytarpheta cayennensis (Verbenaceae were the most visited plants. The Botanical Garden of UFSM is an example of an urban park that seems to provide floral resources for the feeding of many butterfly species, being also a potential refuge for species from forest areas nearby.

[Association between rs10938397 polymorphism in GNPDA2 and obesity in children at different stages of development].

Science.gov (United States)

Gao, L W; Zhang, M X; Wu, L J; Fu, L W; Zhao, X Y; Mi, J

2018-01-10

Objective: To examine the association between rs10938397 polymorphism in glucosamine-6-phosphate deaminase 2 ( GNPDA2 ) and risk of obesity in children at different stages of development and analyze the differences in the association. Methods: A total of 3 503 school-aged children were selected from the Beijing Child and Adolescent Metabolic Syndrome (BCAMS) study in Beijing and their complete anthropometry weight, height, fat mass percentage (FMP), fat mass index (FMI) and free fat mass index (FFMI) and sexual maturation (SM) data were used. The developmental stages were evaluated using male testicular volume and female breast Tanner staging. FMP, FM and FFM were measured by bioelectrical impedance analysis. General obesity and adiposity were respectively defined according to Chinese sex-age-specific body mass index (BMI) cutoffs and sex-age-specific FMP cutoffs. The SNP rs10938397 were genotyped by the TaqMan Allelic Discrimination Assay with the GeneAmp 7900 sequence detection system (Applied Biosystems, Foster city, CA, USA). Relationships between rs10938397 polymorphism and BMI, FMP, FMI and FFMI and different types of obesity were tested using multivariate linear regression and logistic regression models. Results: After age adjustment and correction for multiple testing, the rs10938397-G was associated with BMI and risk of general obesity in boys in early puberty ( β =0.328, P =0.001; OR =1.420, 95% CI : 1.126-1.790), and the rs10938397-G was associated with BMI in girls in late puberty ( β =0.266, P =0.001). The associations of GNPDA2 rs10938397-G with FFMI and FMI were observed in boys in early puberty ( β =0.137, P =0.016; β =0.202, P =0.007) and the associations of rs10938397-G with FMP and FMI were observed in girls in late puberty ( β =0.153, P =0.002; β =0.168, P =0.001). The rs10938397-G was also associated with adiposity in girls in late puberty ( OR =1.339, 95% CI : 1.093-1.637). Conclusion: The rs10938397 polymorphism in GNPDA2 is associated

The transition radiation detector of the CBM experiment at FAIR

Energy Technology Data Exchange (ETDEWEB)

Bergmann, Cyrano [Institut fuer Kernphysik, WWU Muenster (Germany)

2016-07-01

The Compressed Baryonic Matter (CBM) experiment is a fixed target heavy-ion experiment at the future FAIR accelerator facility. The CBM Transition Radiation Detector (TRD) is one of the key detectors to provide electron identification above momenta of 1 GeV/c and charged particle tracking. Due its capability to identify charged particles via their specific energy loss, the TRD in addition will provide valuable information for the measurement of fragments. These requirements can be fulfilled with a XeCO{sub 2} based Multi-Wire Proportional Counter (MWPC) detector in combination with an adequate radiator. The default MWPC is composed of a symmetric amplification area of 7 mm thickness, followed by a 5 mm drift region to enhance the TR-photon absorption probability in the active gas volume. This geometry provides also efficient and fast signal creation, as well as read-out, of the order of 200 μs per charged particle track. The performance of this detector is maximized by reducing the material budget between the radiator and gas volume to a minimum. The full detector at SIS100 will be composed of 200 modules in 2 sizes. To limit cost and production time the number of various module types is limited to 6 types and 4 types of Front End Board (FEB) flavors are required. An overview of the design and performance of the TRD detector is given.

Performance study of the anisotropic flow and reaction plane reconstruction in the CBM experiment

International Nuclear Information System (INIS)

Mikhaylov, V; Kugler, A; Kushpil, V; Tlustý, P; Selyuzhenkov, I

2016-01-01

The Projectile Spectator Detector (PSD) is a subsystem of the CBM experiment at the future FAIR facility designed to determine centrality and reaction plane orientation in the heavy-ion collisions. It will be done by measurement of the energy distribution of the heavy nucleons and nuclei fragments emitted close to the beam rapidity in forward direction. For the anticipated beam energies of FAIR SIS100 and SIS300 accelerators, different event generators (iQMD, UrQMD, DCM-QGSM, LA-QGSM and HSD) were used for the study of directed and elliptic proton flow in Au+Au collisions. Produced particles were transported with the GEANT4 Monte-Carlo using the CBM detector geometry. Performance of the reaction plane determination is shown for different PSD setups to demonstrate effects of the detector granularity and magnetic field. Simulation results are compared with the FOPI, AGS E877, E895 and STAR experimental data. (paper)

Key technology for treating slack coal blockage in CBM recovery: A case study from multi-lateral horizontal wells in the Qinshui Basin

Directory of Open Access Journals (Sweden)

Yong Yang

2016-01-01

Full Text Available Due to the nature of coal bed, slack coal production is inevitable in gas recovery sby water drainage. When coalbed methane (CBM wells are reentered after low energy exploitation and shut-in, the negative effect of slack coal production on productivity of CBM is irreversible. In this paper, the CBM occurrence characteristics and multi-lateral horizontal well trajectory in the Qinshui Basin, Shanxi Province, were analyzed. In the multi-lateral horizontal wells, the expected gas production rate could not be reached and the production rate after shut-in maintenance could not restore to the level before shut-in. The reason for these issues is that migration pathways in the reservoirs are blocked by slack coal deposits, while formation water and slack coal deposit accumulated at the troughs of horizontal sections enlarge the resistance for gas to flow into the bottom hole. Furthermore, three key technologies to deal with slack coal blockage were proposed. Firstly, CBM horizontal well trajectory should follow the principle of keeping the wellbores smooth and updip instead of being “wavy”, on the premise of guaranteeing CBM drilling rate. Secondly, the cavities of production wells, as an important part of multi-lateral horizontal wells, are capable of settling sand, and can be used for gas–liquid–solid separation. And thirdly, a tree-like horizontal well with its main hole set on stable seam top or floor, provides a stable well flushing passage for coal powder. This research provides a useful attempt in solving the problem of slack coal production in gas recovery by water drainage.

The Drosha rs10719 T>C polymorphism is associated with preeclampsia susceptibility.

Science.gov (United States)

Rezaei, Mahnaz; Eskandari, Fatemeh; Mohammadpour-Gharehbagh, Abbas; Teimoori, Batool; Yaghmaei, Minoo; Mokhtari, Mojgan; Salimi, Saeedeh

2018-01-01

Drosha is a member of the micro RNA (miRNA) processing machinery that affects miRNA processing. Single-nucleotide polymorphisms (SNPs) in the Drosha gene might affect microRNA processing and the expression of various genes. The aim of this study is to investigate the association between SNPs in the Drosha gene and preeclampsia (PE) in the southeast of Iran. Genotyping of Drosha rs10719 and rs6877842 was performed using blood samples from 219 PE women and 205 healthy control subjects by a polymerase chain reaction-restriction fragment length polymorphism method. The Drosha rs10719TC genotype was significantly associated with 1.6-fold higher risk of PE (odds ratio (OR, 1.6 [95% CI, 1.1-2.4], P = 0.026). In addition, the frequency of the Drosha rs10719CC genotype was significantly higher in PE women and was associated with threefold higher risk of PE (OR 3 [95% CI 1.4-6.3], P = 0.004). There was no association between the Drosha rs6877842 polymorphism and PE susceptibility. The CC-GG combined genotype was associated with 3.4-fold higher risk of PE (OR 3.4 [95% CI 1.4-8.1], P = 0.007). The haplotype-based association analysis showed higher frequency of C-G haplotype of Drosha rs10719 and rs6877842 polymorphisms with the increased risk of PE 1.5-fold (OR 1.5 [95% CI 1.1 - 2], P = 0.01). The Drosha rs10719TC and CC genotypes were associated with PE risk. The CC-GG combined genotype and C-G haplotype of Drosha rs10719 and rs6877842 polymorphisms may increase PE susceptibility.

CBM maze-scores as indicators of reading level and growth for seventh-grade students

NARCIS (Netherlands)

Chung, S.; Espin, C.A.; Stevenson, C.E.

The technical adequacy of CBM maze-scores as indicators of reading level and growth for seventh-grade secondary-school students was examined. Participants were 452 Dutch students who completed weekly maze measures over a period of 23 weeks. Criterion measures were school level, dyslexia status,

Optimisation of beam-pipe shielding for MUCH detector of CBM experiment

International Nuclear Information System (INIS)

Ahmad, S.; Farooq, M.; Chattopadhyay, S.

2014-01-01

The Compressed Baryonic Matter (CBM) experiment is one of the major scientific pillars of FAIR. The main goal of the experiment is to explore the Quantum Chromodynamics (QCD) phase diagram in the regions of high baryonic densities and moderate temperatures in the beam energy range of 10-45 AGeV. This includes also the search for the critical point, the first order deconfinement phase transition from the hadronic matter to the partonic matter and the study of equation-of-state of dense baryonic matter. The CBM research program comprises a comprehensive scan of observables, beam energies and collision systems. The observables includes low-mass dilepton pairs, charmonia and open charm, but also collective flow of rare and bulk particles, correlations and fluctuations. Some of the particles under study have low cross-sections (like charm) or small branching ratios (like low-mass vector mesons). Therefore, in order to compensate for the low yield the measurements have to be performed at very high reaction rates of up to about 10 MHz. These conditions demand for fast and radiation hard detectors and associated fast electronics, readout and online event reconstruction. Low material budget is required with in the detector acceptance to avoid multiple scattering which would limit high-precision measurements

ZONEAMENTO GEOAMBIENTAL DO PERÍMETRO URBANO DE SANTA MARIA – RS, BRASIL

Directory of Open Access Journals (Sweden)

Carlos Alberto da Fonseca Pires

2011-12-01

Full Text Available O presente trabalho de pesquisa tem por objetivo a caracterização geoambiental da paisagem, através da elaboração de Zoneamento Geoambiental do Perímetro Urbano de Santa Maria, Rio Grande do Sul. O perímetro urbano, cujos limites foram definidos pela municipalidade, possui uma área de 13.092 ha e engloba as áreas urbanas e as de possível urbanização. A pesquisa foi desenvolvida tendo como referencial teórico a análise sistêmica, utilizando-se da paisagem como categoria de análise, e como instrumental metodológico a utilização de geotecnologias, especialmente de SIGs. O tratamento metodológico segue a proposta metodológica desenvolvida pelo LAGEOLAM/UFSM, com algumas adaptações. Os atributos utilizados na análise geoambiental compreendem as características climáticas, o substrato geológico, a hidrologia, a geomorfologia, as feições superficiais e o uso e ocupação do solo. A espacialização destes componentes da paisagem, exceto as informações climáticas, através da elaboração de mapas temáticos, e a posterior integração, por meio de uma representação de síntese, foi realizada no software Spring 4.3.3, que permitiu a manipulação de dados de diferentes fontes. Como produto final estabeleceu-se uma hierarquia composta por nove unidades geoambientais, seis subunidades e quatro feições. A elaboração do zoneamento geoambiental, através do estudo integrado da paisagem, constitui numa importante ferramenta no gerenciamento dos recursos da área.

Lack of association between rheumatoid arthritis and genetic variants rs10889677, rs11209026 and rs2201841 of IL-23R gene.

Science.gov (United States)

Paradowska-Gorycka, Agnieszka; Malinowski, Damian; Haladyj, Ewa; Olesinska, Marzena; Safranow, Krzysztof; Pawlik, Andrzej

2018-01-19

Rheumatoid arthritis (RA) is an autoimmune diseases, where different genetic variants in cytokine genes may play a pathogenic role. A GWAS in autoimmune diseases highlighted the IL-23R gene as a one of the susceptibility factors. We examined three candidate single nucleotide polymorphisms (SNPs) rs10889677, rs11209026 and rs2201841 of the IL-23R gene, as well as determined their possible association with RA in a Polish population. The IL-23R gene polymorphisms were genotyped for 422 RA patients and 348 healthy individuals using TaqMan SNP genotyping assay. The genotypes frequency did not deviate from HWE in each examined group. A comparison of the allele as well as genotype frequencies of the IL-23R polymorphisms under codominant, dominant and recessive genetic model revealed no significant differences between RA patients and healthy subjects. We also demonstrated that IL-23R rs2201841 and rs11209026 as well as rs11209026 and rs10889677 were in complete linkage disequilibrium (D'=1.0). Our genotype-phenotype analysis demonstrated that in carriers of rs10889677C and/or rs2201841A allele the RF, extra-articular manifestations and erosion were more frequent present than in patients with rs10889677A and/or rs2201841A allele, although this association was not significant. Present findings indicated that the autoimmune disease-associated genetic variants in IL-23R gene are not associated with RA in the Polish population. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

Measurement of rare probes with the silicon tracking system of the CBM experiment at FAIR

International Nuclear Information System (INIS)

Heuser, Johann; Friese, Volker

2014-01-01

The Compressed Baryonic Matter (CBM) experiment at FAIR will explore the phase diagram of strongly interacting matter at highest net baryon densities and moderate temperatures. The CBM physics program will be started with beams delivered by the SIS 100 synchrotron, providing energies from 2 to 14 GeV/nucleon for heavy nuclei, up to 14 GeV/nucleon for light nuclei, and 29 GeV for protons. The highest net baryon densities will be explored with ion beams up to 45 GeV/nucleon energy delivered by SIS 300 in the next stage of FAIR. Collision rates up to 10 7 per second are required to produce very rare probes with unprecedented statistics in this energy range. Their signatures are complex. These conditions call for detector systems designed to meet the extreme requirements in terms of rate capability, momentum and spatial resolution, and a novel DAQ and trigger concept which is not limited by latency but by throughput. In this paper we outline the concepts of CBM's central detector, the Silicon Tracking System, and of the First-Level Event Selector, a dedicated computing farm to reduce on-line the raw data volume by up to three orders of magnitude to a recordable rate. Progress with the development of detector and software algorithms are discussed and examples of performance studies on the reconstruction of rare probes at SIS 100 and SIS 300 energies given

CBM First-level Event Selector Input Interface Demonstrator

Science.gov (United States)

Hutter, Dirk; de Cuveland, Jan; Lindenstruth, Volker

2017-10-01

CBM is a heavy-ion experiment at the future FAIR facility in Darmstadt, Germany. Featuring self-triggered front-end electronics and free-streaming read-out, event selection will exclusively be done by the First Level Event Selector (FLES). Designed as an HPC cluster with several hundred nodes its task is an online analysis and selection of the physics data at a total input data rate exceeding 1 TByte/s. To allow efficient event selection, the FLES performs timeslice building, which combines the data from all given input links to self-contained, potentially overlapping processing intervals and distributes them to compute nodes. Partitioning the input data streams into specialized containers allows performing this task very efficiently. The FLES Input Interface defines the linkage between the FEE and the FLES data transport framework. A custom FPGA PCIe board, the FLES Interface Board (FLIB), is used to receive data via optical links and transfer them via DMA to the host’s memory. The current prototype of the FLIB features a Kintex-7 FPGA and provides up to eight 10 GBit/s optical links. A custom FPGA design has been developed for this board. DMA transfers and data structures are optimized for subsequent timeslice building. Index tables generated by the FPGA enable fast random access to the written data containers. In addition the DMA target buffers can directly serve as InfiniBand RDMA source buffers without copying the data. The usage of POSIX shared memory for these buffers allows data access from multiple processes. An accompanying HDL module has been developed to integrate the FLES link into the front-end FPGA designs. It implements the front-end logic interface as well as the link protocol. Prototypes of all Input Interface components have been implemented and integrated into the FLES test framework. This allows the implementation and evaluation of the foreseen CBM read-out chain.

Constituição e funcionamento do Conselho Municipal de Educação frente ao processo de democratização da gestão: um estudo dos municípios de Santa Maria e Santa Rosa/RS Constituición y funcionamiento del Consejo Municipal de Educación frente al proceso de democratización de la gestión: un estudio de los municipios de Santa Maria y Santa Rosa/RS Constitution and operation of the Municipal Council of Education before regarding the process of democratizing management: a study about the municipalities of Santa Maria and Santa Rosa

Directory of Open Access Journals (Sweden)

Sueli Menezes Pereira

2011-09-01

Full Text Available O artigo parte de um estudo qualitativo, calcado em uma pesquisa bibliográfica e documental com objetivo de discutir aspectos referentes à constituição e funcionamento do Conselho Municipal de Educação (CME, como órgão colegiado que se reveste de importante significado para a democratização da gestão educacional. A ênfase da análise recai sobre os CMEs dos municípios gaúchos de Santa Maria e Santa Rosa que, dadas as suas diferenças e peculiaridades, projetam tais órgãos ainda atrelados a uma estrutura formal intermediária. O desafio dos CMEs é funcionar de forma autônoma frente as suas inúmeras atribuições de modo a dar respostas que sinalizem à criação de novos caminhos à educação pública municipal. Atuar de forma diferenciada em um cenário onde a maioria dos conselhos se alinham a uma lógica formal e burocratizada e onde ainda são vistos como órgão de assessoramento do poder governamental é, sem dúvida, uma meta a ser perseguida na busca da democratização deste espaço público.El artículo parte de un estudio cualitativo, basado en una investigación bibliográfica y documental con el objeto de discutir aspectos referentes a la constitución y al funcionamiento del Consejo Municipal de Educación (CME, como órgano colegiado que tiene importante significado para la democratización de la gestión educacional. El énfasis del análisis se concentra en los CMEs (Consejos Municipales de Educación de los municipios de Santa María y Santa Rosa del Estado de Rio Grande do Sul, Brasil, que, en razón de sus diferencias y peculiaridades proyectan los referidos órganos todavía arraigados a una estructura formal intermediaria. El desafio de los CMEs es poder funcionar de forma autónoma frente a sus innumerables atribuciones para dar respuestas que orienten la creación de nuevos caminos hacia la educación pública municipal. Actuar de manera distinta en un escenario en que la mayoría de los consejos se

Read-out concepts for FPGA-based sub-systems within the CBM detector

Energy Technology Data Exchange (ETDEWEB)

Michel, Jan [Goethe-Universitaet Frankfurt (Germany); Collaboration: CBM-Collaboration

2015-07-01

The Compressed Baryonic Matter experiment (CBM) to be built at FAIR consists of several individual sub-detectors. Some are based on custom ASICs as front-ends. Others employ FPGA based modules where extensive slow control features can be implemented to ease the recording of data and to allow for fast detection of any kind of error condition. Being designed as a free-running data acquisition, the demands also include a synchronized read-out, i.e. distribution of a common clock signal to all modules. To reduce the complexity of wiring, this is to be done sharing the same optical fibers as the data transport. During the past years, TrbNet has been designed and is used in various experiments, initially for the HADES experiment at FAIR. This protocol can now serve as a platform for the CBM read-out. In several steps, synchronous links with deterministic latency, as well as a free-streaming data transport can be included. At the same time, modifications to improve bandwidth and provide compatibility to the CERN GBTx links used for ASIC based sub-systems are to be developed. This contribution shows the planned steps as well as the current status of development.

Studi Awal Desain LNG (Liquefied Natural Gas Plant Dari Coal Bed Methane (CBM Dengan Kapasitas Feed 40 MMSCFD

Directory of Open Access Journals (Sweden)

Muhammad Fahmi

2013-09-01

Full Text Available Dalam penelitian ini telah dilakukan perancangan Liquefied Natural Gas (LNG Plant dari CBM degan kapasitas feed 40 MMSCFD dan waktu operasi 24 jam/hari dan 330 hari/tahun. Perancangan LNG plant dari CBM ini bertujuan untuk membantu usaha Negara dalam melakukan diversifikasi energi untuk mengatasi krisis energi. Salah satu contoh diversifikasi energi adalah mengganti bahan bakar pembangkit listrik High Speed Diesel (HSD menjadi LNG yang harganya relative lebih murah. Penelitian ini didasarkan pada simulasi dengan Aspen HYSYS, dimana terdapat batasan penelitian yakni gas alam yang dicairkan dengan cara didinginkan pada temperatur sekitar -161.3oC dan pada tekanan 1.06 bar. Tujuan pabrik LNG ini adalah Provinsi Bali hal ini dikarenakan elektrifikasi daerah tersebut cukup rendah. Dengan konsumsi minyak HSD yang tinggi tetapi elektrifikasi yang rendah maka diperlukan sumber energi alternatif untuk meningkatkan daya yang dihasilkan dan area distribusi sehingga tingkat elektrifikasi akan menjadi lebih tinggi. Pabrik LNG ini didirikan di Muara Enim, Sumatera Selatan pada tahun 2016. Penentuan lokasi pabrik berorientasi pada ketersediaan sumber bahan baku CBM. Menurut data DITJEN MIGAS Muara enim memiliki potensi CBM sebesar 0.5 TCF. Potensi sebesar ini dapat digunakan selama 60 tahun dengan kapasitas feed LNG plant sebesar 40 MMSCFD Proses pembuatan LNG dari gas alam ini menggunakan Proses On-Shore LNG menggunakan beberapa rangkaian proses yaitu : Unit Penghilang CO2 dan H2S : menggunakan Amine Cycle, Unit Dehidrasi : menggunakan molecular sieve, Unit Refrigeran dan Pencairan : menggunakan MCR Coldbox Sumber dana investasi berasal dari modal sendiri sebesar 20 % biaya investasi dan pinjaman jangka pendek sebesar 80 % biaya investasi dengan bunga sebesar 12 % per tahun. Dari analisa perhitungan ekonomi didapat hasil-hasil sebagai berikut : Investasi : 163,557 MUSD, Internal Rate of Return : 25.66 %, POT : 3.26 tahun, BEP : 58.86 %, NPV 10 year   :120

Investigation of surface homogeneity of mirrors for the CBM-RICH detector and low-mass di-electron feasibility studies

International Nuclear Information System (INIS)

Lebedeva, E; Hoehne, C

2014-01-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR facility will investigate high net-baryon density matter at moderate temperatures in A+A collisions from 4-45 AGeV. One of the key observables of the CBM physics program is electromagnetic radiation as a probe of strongly interacting matter in heavy-ion collisions, carrying undistorted information on its conditions to the detector. This includes detailed investigations of low-mass vector mesons in their di-electron channel. A clean and efficient identification of electrons is required for such measurements. In CBM the electron identification will be performed by a Ring Imaging Cherenkov detector and several layers of Transition Radiation Detectors. The RICH detector will be operated with CO 2 radiator gas, MAPMTs as photodetector and spherical glass mirrors as focusing elements. A high quality of the mirrors in terms of reflectivity and surface homogeneity is required. In the first part of the contribution results on measurements of the mirror surface homogeneity are presented. Results on the feasibility studies of low-mass di-electron measurements with realistic detector response are discussed in the second part of the contribution.

Multidimensional Space-Time Methodology for Development of Planetary and Space Sciences, S-T Data Management and S-T Computational Tomography

Science.gov (United States)

Andonov, Zdravko

This R&D represent innovative multidimensional 6D-N(6n)D Space-Time (S-T) Methodology, 6D-6nD Coordinate Systems, 6D Equations, new 6D strategy and technology for development of Planetary Space Sciences, S-T Data Management and S-T Computational To-mography. . . The Methodology is actual for brain new RS Microwaves' Satellites and Compu-tational Tomography Systems development, aimed to defense sustainable Earth, Moon, & Sun System evolution. Especially, extremely important are innovations for monitoring and protec-tion of strategic threelateral system H-OH-H2O Hydrogen, Hydroxyl and Water), correspond-ing to RS VHRS (Very High Resolution Systems) of 1.420-1.657-22.089GHz microwaves. . . One of the Greatest Paradox and Challenge of World Science is the "transformation" of J. L. Lagrange 4D Space-Time (S-T) System to H. Minkovski 4D S-T System (O-X,Y,Z,icT) for Einstein's "Theory of Relativity". As a global result: -In contemporary Advanced Space Sciences there is not real adequate 4D-6D Space-Time Coordinate System and 6D Advanced Cosmos Strategy & Methodology for Multidimensional and Multitemporal Space-Time Data Management and Tomography. . . That's one of the top actual S-T Problems. Simple and optimal nD S-T Methodology discovery is extremely important for all Universities' Space Sci-ences' Education Programs, for advances in space research and especially -for all young Space Scientists R&D!... The top ten 21-Century Challenges ahead of Planetary and Space Sciences, Space Data Management and Computational Space Tomography, important for successfully de-velopment of Young Scientist Generations, are following: 1. R&D of W. R. Hamilton General Idea for transformation all Space Sciences to Time Sciences, beginning with 6D Eukonal for 6D anisotropic mediums & velocities. Development of IERS Earth & Space Systems (VLBI; LLR; GPS; SLR; DORIS Etc.) for Planetary-Space Data Management & Computational Planetary & Space Tomography. 2. R&D of S. W. Hawking Paradigm for 2D

Genetic differentiation between marine iguanas from different breeding sites on the island of Santa Fe (Galapagos Archipelago).

Science.gov (United States)

Lanterbecq, Deborah; Glaberman, Scott; Vitousek, Maren Noelani; Steinfartz, Sebastian; Benavides, Edgar; Wikelski, Martin; Caccone, Adalgisa

2010-01-01

We studied patterns of genetic diversity within and among 5 populations (318 individuals) of Galápagos marine iguanas (Amblyrhynchus cristatus) from the island Santa Fé. Populations were separated by distances of 0.2 to 9.9 km. We sequenced 1182 base pairs of the mitochondrial control region and screened 13 microsatellite loci for variability. We also added data from 5 populations (397 individuals) sampled on 4 neighboring islands (Santa Cruz, Floreana, Espanola, and San Cristobal). The 5 Santa Fé populations, revealed as genetically distinct from populations on other islands, present relatively low levels of genetic diversity, which are similar for both microsatellite (average observed heterozygosity from 0.7686 to 0.7773) and mitochondrial DNA (mtDNA) markers (haplotypic and nucleotide diversity from 0.587 to 0.728 and from 0.00079 to 0.00293, respectively), and comparable with those observed in similar-sized sampling sites on other islands. There was frequency-based evidence of genetic structure between northern and southern sites on Santa Fé (F(st) of 0.0027-0.0115 for microsatellite and 0.0447-0.2391 for mtDNA), but the 4 southern sites showed little differentiation. Most of the intra-island genetic variation was allocated within rather than between sites. There was no evidence of sex-biased dispersal or population substructuring due to lek-mating behavior, suggesting that these 2 observed behaviors are not strong enough to leave an evolutionary signal on genetic patterns in this species.

The silicon tracking system of the CBM experiment at FAIR

Energy Technology Data Exchange (ETDEWEB)

Singla, Minni [GSI Darmstadt (Germany); Collaboration: CBM-Collaboration

2015-07-01

The Compressed Baryonic Matter (CBM) experiment, one of the major scientific pillars at FAIR, will explore the phase diagram of strongly interacting matter at the highest net-baryon densities in nucleus-nucleus collisions with interaction rates up to 10 MHz. The Silicon Tracking System is the central detector system of the CBM experiment. Its task is to perform track reconstruction and momentum determination for all charged particles created in beam-target collisions at SIS 100 and SIS 300 beam energies. The technical challenges to meet are a high granularity matching the high track densities, a fast self-triggering read-out coping with high interaction rates, and a low mass to yield high momentum resolution of Δp/p=1%. The detector system acceptance covers polar angles between 2.5 and 25 degrees and will be operated in the 1 T field of a superconducting dipole magnet. We introduce the concept of the STS, being comprised of eight tracking stations employing ∝1300 double-sided silicon microstrip sensors on modular structures that keep the read-out electronics outside the physics aperture. Ultra-thin-multiline micro-cables will be used to bridge the distance between the microstrip sensors and the readout electronics. Infrastructure such as power lines and cooling plates will be placed at the periphery of the stations. The status of the STS development is summarized in the presentation, including an overview on sensors, read-out electronics, prototypes, and system integration.

Characterization of silicon microstrip sensors, front-end electronics, and prototype tracking detectors for the CBM experiment at FAIR

International Nuclear Information System (INIS)

Sorokin, Iurii

2013-01-01

The Compressed Baryonic Matter (CBM) experiment will explore the phase diagram of strongly interacting matter in the region of high net baryonic densities. The matter at the extreme conditions will be studied in collisions of a heavy ion beam with a fixed heavy element target. The present work is devoted to the development of the main component of the CBM experiment - the Silicon Tracking System (STS). The STS has to enable reconstruction of up to 1000 charged particle tracks per nucleus-nucleus interaction at the rate of up to 10 MHz, provide a momentum resolution Δp/p of 1 %, and withstand the radiation load of up to 10 14 n eq /cm 2 (n eq -neutron equivalent). The STS will be based on double-sided silicon microstrip sensors, that will be arranged in 8 planes in the aperture of the dipole magnet. Selftriggering readout electronics will be located on the periphery of the detecting planes, and connected to the sensors with low mass microcables. In the stage of R and D, as well as in the stages of pre-series and series production, characterization of the sensors, of the front-end electronics, and of the complete detector modules has to be performed. In the present work the required techniques were developed, and the performance of the latest detector prototypes was evaluated. A particular attention is paid to evaluation of the signal amplitude, as it is one of the most important detector characteristics. Techniques for measuring the passive electrical characteristics of the sensors were developed. These include: the coupling and the interstrip capacitances, the interstrip resistance, the bias resistance, the strip leakage current, the bulk capacitance, and the bulk leakage current. The techniques will be applied for the quality assurance of the sensors during the pre-series and the series production. Extensive characterization of the prototype readout chip, n-XYTER, was performed. The register settings were optimized, and the dependence of the amplitude response on

Promoter polymorphisms of ST3GAL4 and ST6GAL1 genes and associations with risk of premalignant and malignant lesions of the cervix.

Science.gov (United States)

Rivera-Juarez, Maria de Los Angeles; Rosas-Murrieta, Nora Hilda; Mendieta-Carmona, Victoriano; Hernandez-Pacheco, Raquel Esneidy; Zamora-Ginez, Irma; Rodea-Avila, Carlos; Apresa-Garcia, Teresa; Garay-Villar, Onix; Aguilar-Lemarroy, Adriana; Jave-Suarez, Luis Felipe; Diaz-Orea, Maria Alicia; Milflores-Flores, Lorena; Reyes-Salinas, Juan Salvador; Ceja-Utrera, Francisco Javier; Vazquez-Zamora, Victor Javier; Vargas-Maldonado, Tomas; Reyes-Carmona, Sandra; Sosa-Jurado, Francisca; Santos-Lopez, Gerardo; Reyes-Leyva, Julio; Vallejo-Ruiz, Veronica

2014-01-01

Sialyltransferase gene expression is altered in several cancers, including examples in the cervix. Transcriptional regulation of the responsible genes depends on different promoters. We aimed to determine the association of single-nucleotide polymorphisms in the B3 promoter of the ST3GAL4 gene and the P1 promoter of the ST6GAL1 gene with cervical premalignant lesions or cervical cancer. A blood sample and/or cervical scrapes were obtained from 104 women with normal cytology, 154 with premalignant lesions and 100 with cervical cancer. We also included 119 blood samples of random donors. The polymorphisms were identified by sequencing from PCR products. For the B3 promoter, a fragment of 506 bp (from nucleotide -408 to +98) was analyzed, and for the P1 promoter a 490 bp (-326 to +164) fragment. The polymorphism analysis showed that at SNP rs10893506, genotypes CC and CT of the ST3GAL4 B3 promoter were associated with the presence of premalignant lesions (OR=2.89; 95%CI 1.72-4.85) and cervical cancer (OR=2.23; 95%CI 1.27-3.91). We detected only one allele of each polymorphism in the ST6GAL1 P1 promoter. We did not detect any genetic variability in the P1 promoter region in our study population. Our results suggest that the rs10893506 polymorphism -22C/T may increase susceptibility to premalignant and malignant lesions of the cervix.

The Calcium-Sensing Receptor Gene Polymorphism rs1801725 and Calcium-Related Phenotypes in Hemodialysis Patients

Directory of Open Access Journals (Sweden)

Alicja E. Grzegorzewska

2018-05-01

Full Text Available Background/Aims: The calcium-sensing receptor gene (CASR rs1801725 variant is responsible for a non-conservative amino-acid change (A986S in the calcium-sensing receptor cytoplasmic tail. We hypothesized that rs1801725 polymorphism might be helpful in understanding Ca-related abnormalities in HD patients. Methods: In 1215 subjects (245 on cinacalcet, we determined the associations of rs1801725 with secondary hyperparathyroidism (sHPT-related laboratory parameters, PTH-decreasing effect of cinacalcet hydrochloride, coronary artery disease (CAD, myocardial infarction (MI, nephrolithiasis-related ESRD, and mortality. CASR rs7652589(Ars1801725(G>T haplotypes and rs1801725 epistatic interactions with vitamin D signaling pathway genes were examined for associations with selected phenotypes. Results: The rs1801725 variant allele showed an increasing independent effect on plasma PTH (Pcorrected = 0.009. CASR rs7652589_rs1801725 AT haplotype was associated with 1.7-fold higher frequency of PTH levels over 437 pg/mL than the reference haplotype GG (P = 0.001. CASR rs7652589_rs1801725 AG haplotype was 1.5-fold more frequent in nephrolithiasis-related ESRD than the GG haplotype (P = 0.004. There were no significant associations between rs1801725, CAD, MI, and response to cinacalcet. Variant homozygosity of rs1801725 correlated independently with higher infection-related mortality compared with heterozygosity (HR 7.95, 95%CI 2.15 – 29.37, P = 0.003 and major homozygosity (HR 5.89, 95%CI 1.69 – 20.55, P = 0.040. CASR rs1801725 did not show epistatic interactions with vitamin D signaling pathway genes concerning tested associations. Conclusion: The variant allele of CASR rs1801725 solely and together with the variant allele of rs7652589 increases risk of more advanced sHPT. Homozygosity of the rs1801725 variant allele contributes to infection-related mortality in HD patients.

Pelaksanaan Sosialisasi Inisiasi Menyusu Dini (IMD di Rumah Sakit St Carolus dan Rumah Sakit Umum Daerah (RSUD Budhi Asih Jakarta

Directory of Open Access Journals (Sweden)

Mujiati Mujiati

2016-02-01

Full Text Available AbstractEarly Breastfeeding Initiation (IMD, followed by exclusive breastfeeding was one of the efforts to improve the health of babies and toddlers. Information about the IMD process has very big influence on the formation of intentions mother who will soon give birth to apply the IMD process postpartum. This type of research was case study. Data collected through in-depth interviews with 30 informants and triangulation of data, as well as the observation of the hospital environment. Hospitals as research areas, namely St. Carolus hospital and Budhi Asih regional general hospital in Jakarta. Analysis of data use content analysis. Socialization in St. Carolus hospital is mandatory activities performed routinely by health personnel, and supported by many media and dissemination of information about the IMD spread in the hospital setting. Media information in the form of posters, banners, banner and photo frame. In the Budhi Asih regional general hospital no socialization of IMD specifically, nor was there any information media because of limited funds. It needs a strong commitment from the hospitals to disseminate IMD so that implementation can be managed optimally.Keywords: socialization, early breastfeeding initation (IMD, hospitalAbstrakInisiasi Menyusu Dini (IMD yang dilanjutkan dengan pemberian ASI Eksklusif merupakan salah satu upaya untuk meningkatkan kesehatan bayi dan balita. Informasi mengenai proses IMD sangat berpengaruh besar pada pembentukan niat ibu yang akan segera melahirkan untuk mau menerapkan proses IMD pasca melahirkan. Jenis penelitian adalah studi kasus dengan pendekatan cross sectional. Pengumpulan data dilakukan melalui wawancara mendalam kepada 30 informan dan juga dilakukan triangulasi data, serta observasi terhadap lingkungan RS. RS yang menjadi lokasi penelitian yaitu RS St. Carolus dan RSUD Budhi Asih di Jakarta. Analisis data menggunakan content analysis. Sosialisasi IMD di RS St. Carolus merupakan kegiatan wajib

Role of myocardial ischemia on exercise-induced ST elevation

International Nuclear Information System (INIS)

Saito, Muneyasu; Sumiyoshi, Tetsuya; Nishimura, Tsunehiko; Uehara, Toshiisa; Hayashida, Kouhei; Haze, Kazuo; Fukami, Ken-ichi; Hiramori, Katsuhiko

1986-01-01

Exercise-induced ST elevation in patients with previous myocardial infarction (MI) has been recognized to be related to left ventricular (LV) asynergy, however it is also recognized that myocardial ischemia can induce ST elevation. In this study, factors which determine the extent of ST elevation, with special reference to myocardial ischemia, was re-evaluated using quantitative analysis of stress myocardial scintigraphy (S-SG). Among 65 patients with previous anterior myocardial infarction and documented single vessel disease of left anterior descending artery (LAD), 19 patients who had exercise-induced ST elevation (ΔST ≥ 2.0 mm) had more abnormal Q waves (p < 0.01), lower LV ejection fraction (EF) (p < 0.01), more severe LV asynergy (p < 0.05) and less incidence of post-MI angina pectoris (AP) (p < 0.01), compared to those with ΔST < 2.0 mm, indicating that ST elevation is primarily related to LV asynergy. Correlation studies among clinical, angiographic and scintigraphic parameters show that ΔST was significantly related to a size of MI represented by Tl score or relative defect Tl activity and number of abnormal Q waves (No.Q), the magnitude of work load expressed by changes in double product (ΔDP) and intervals between the onset and exercise test, as well as myocardial ischemia expressed by the extent of redistribution (%RD) in S-SG. Among 23 patients with post-MI AP, ΔST significantly correlated with %RD (r = 0.47), indicating that myocardial ischemia can be a mechanism of exercise-induced ST elevation in patients with previous MI. Furtheremore, among those with ST elevation, concave-type ST elevation was more related to myocardial ischemia compared to convex-type ST elevation as expressed by the incidence of post-MI AP and/or significant redistribution. (J.P.N.)

CONFLITO SOCIOAMBIENTAL E CONTRADIÇÕES DO ESPAÇO SOCIAL: o caso do polo naval de Rio Grande/RS

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Rafaella Egues da Rosa

Full Text Available Os autores analisam o conflito socioambiental protagonizado pela empresa de construção de plataformas offshore Quip S/A e os pescadores do bairro Santa Tereza na cidade de Rio Grande, RS. Além da consulta de fontes secundárias, realizaram-se entrevistas com os pescadores da comunidade. A partir da teoria lefebvriana do espaço social, foi possível mostrar que os denominados conflitos socioambientais são expressão das contradições do espaço social e que, muitas vezes, esse caráter fica oculto no discurso ambiental.

Surface thermodynamic stability, electronic and magnetic properties in various (001) surfaces of Zr2CoSn Heusler alloy

Science.gov (United States)

Yang, Yan; Feng, Zhong-Ying; Zhang, Jian-Min

2018-05-01

The spin-polarized first-principles are used to study the surface thermodynamic stability, electronic and magnetic properties in various (001) surfaces of Zr2CoSn Heusler alloy, and the bulk Zr2CoSn Heusler alloy are also discussed to make comparison. The conduction band minimum (CBM) of half-metallic (HM) bulk Zr2CoSn alloy is contributed by ZrA, ZrB and Co atoms, while the valence band maximum (VBM) is contributed by ZrB and Co atoms. The SnSn termination is the most stable surface with the highest spin polarizations P = 77.1% among the CoCo, ZrCo, ZrZr, ZrSn and SnSn terminations of the Zr2CoSn (001) surface. In the SnSn termination of the Zr2CoSn (001) surface, the atomic partial density of states (APDOS) of atoms in the surface, subsurface and third layers are much influenced by the surface effect and the total magnetic moment (TMM) is mainly contributed by the atomic magnetic moments of atoms in fourth to ninth layers.

Association of STAT4 rs7574865 and PTPN22 rs2476601 polymorphisms with rheumatoid arthritis and non-systemically reacting antibodies in Egyptian patients.

Science.gov (United States)

El-Lebedy, Dalia; Raslan, Hala; Ibrahim, Alshaymaa; Ashmawy, Ingy; El-Aziz, Shereen Abd; Mohammed, Asmaa M

2017-09-01

The aim of this study was to investigate association of protein tyrosine phosphatase non-receptor type 22 (PTPN22) rs2476601 and signal transducer and activator of transcription 4 (STAT4) rs7574865 polymorphisms with rheumatoid arthritis (RA) susceptibility and to assess potential association with the status of rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP) antibodies, serum neopterin, and disease activity. RF, anti-CCP antibodies, and neopterin were assayed in serum of 100 unrelated RA patients and 114 controls. STAT4 rs7574865 G/T and PTPN22 rs2476601 C/T polymorphisms were genotyped by the TaqMan allelic discrimination method. The frequency of STAT4 variant allele was significantly higher in RA patients than in controls (p = 0.01), while the variant allele of PTPN22 was identified in only two RA patients, in a heterozygous form and in none of control subjects. The frequency of STAT4 variant allele carrier genotypes (GT+TT) was significantly higher among RA patients than in controls (43.7 vs. 10.5%, p = 0.02) and associated with RA under additive and dominant models. The frequency of RF and anti-CCP positivity was significantly higher among RA patients carrying T allele genotypes compared to patients carrying wild genotype (P = 0.02 and 0.04, respectively). No significant associations between STAT4 variant and serum neopterin or disease activity parameters were identified. Our study confirmed the association of STAT4 rs7574865 polymorphism with RA and was the first to indicate an association with RF and anti-CCP antibodies positivity. We also found PTPN22 rs2476601 has no role in susceptibility to RA in Egyptian patients.

Fauna do solo em áreas com Eucalyptus spp. E Pinus elliottii, Santa Maria, RS

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Maria Izabel Jacques Soares

2001-01-01

Full Text Available This work started in the spring in 1996 and finished in the winter in 1997 and it had as its objective to study the populational survey of soil fauna in the Pinus elliotti and Eucalyptus spp. in areas situaded in “Campus” at Federal University of Santa Maria, Rio Grande do Sul, Brazil. An extractor was utilized to collect the soil from 10 sample points, in the 0-5, 5-10, 10-15 and 15-20 cm of soil depth, in each season of the year. With this study it was possible to identify some representants of Phylum Annelida and Arthropoda who belong to fauna-soil-vegetable context. The individual total, its percentile and number of individual for square meter were obtained. It was observed the predominance of Phylum Arthropoda and, in special, of Insecta class in the Eucalyptus spp. area; and the Phylum Annelida in the Pinus elliottii area. The depth variable originated mathematical models to explain the populational distribution for each studied areas. The seasons of year variable did not show a significative difference. It was not possible to establish a populational distribution model.

Conception and design of a control and monitoring system for the mirror alignment of the CBM RICH detector

Science.gov (United States)

Adamczewski-Musch, J.; Akishin, P.; Becker, K.-H.; Belogurov, S.; Bendarouach, J.; Boldyreva, N.; Deveaux, C.; Dobyrn, V.; Dürr, M.; Eschke, J.; Förtsch, J.; Heep, J.; Höhne, C.; Kampert, K.-H.; Kochenda, L.; Kopfer, J.; Kravtsov, P.; Kres, I.; Lebedev, S.; Lebedeva, E.; Leonova, E.; Linev, S.; Mahmoud, T.; Michel, J.; Miftakhov, N.; Niebur, W.; Ovcharenko, E.; Patel, V.; Pauly, C.; Pfeifer, D.; Querchfeld, S.; Rautenberg, J.; Reinecke, S.; Riabov, Y.; Roshchin, E.; Samsonov, V.; Schetinin, V.; Tarasenkova, O.; Traxler, M.; Ugur, C.; Vznuzdaev, E.; Vznuzdaev, M.

2017-12-01

The Compressed Baryonic Matter (CBM) experiment at the future Facility for Anti-proton and Ion Research (FAIR) will investigate the phase diagram of strongly interacting matter at high net-baryon density and moderate temperature in A+A collisions. One of the key detectors of CBM to explore this physics program is a Ring Imaging CHerenkov (RICH) detector for electron identification. For a high performance of the RICH detector precise mirror alignment is essential. A three-step correction cycle has been developed, which will be discussed: First a qualitative, fast check of the mirror positions, second a quantitative determination of possible misalignments and third a software correction routine, allowing a proper functioning of the RICH under misalignment conditions.

The Development of the easyCBM CCSS Reading Assessments: Grade 3. Technical Report #1221

Science.gov (United States)

Alonzo, Julie; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we document the development and piloting of easyCBM reading measures aligned to the Common Core State Standards, designed for use in screening students at risk for reading difficulty and monitoring their progress as they develop reading skills. The measures, which assess students' ability to respond to…

Fabrication and photovoltaic performance of niobium doped TiO{sub 2} hierarchical microspheres with exposed {001} facets and high specific surface area

Energy Technology Data Exchange (ETDEWEB)

Liu, Yongqiang; Ran, Huili [School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001 (China); State Centre for International Cooperation on Designer Low-Carbon and Environmental Materials, Zhengzhou University, Zhengzhou 450001 (China); Fan, Jiajie, E-mail: fanjiajie@zzu.edu.cn [School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001 (China); State Centre for International Cooperation on Designer Low-Carbon and Environmental Materials, Zhengzhou University, Zhengzhou 450001 (China); Zhang, Xiaoli; Mao, Jing [School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001 (China); State Centre for International Cooperation on Designer Low-Carbon and Environmental Materials, Zhengzhou University, Zhengzhou 450001 (China); Shao, Guosheng [School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001 (China); State Centre for International Cooperation on Designer Low-Carbon and Environmental Materials, Zhengzhou University, Zhengzhou 450001 (China); Institute for Renewable Energy and Environmental Technologies, University of Bolton, Bolton BL3 5AB (United Kingdom)

2017-07-15

Highlights: • Nb-doped hierarchical TiO{sub 2} microsphere DSSCs show enhanced performance. • Nb{sup 5+} dopant replaces Ti{sup 4+} cation in TiO{sub 2} lattice. • Electrons transport was enhanced due to the down-shifted conduction band minimum. • Exposed (001) facets and high specific surface area allows high dye-loading. - Abstract: The niobium doped hierarchical anatase TiO{sub 2} microspheres, which are consist of a serried nano-thorns and plicate nano-ribbons with exposed {001} facets, were synthesized using hydrothermal method followed by heat treatment. The effects of niobium on the microstructures and photovoltaic performances of the dye-sensitized solar cells (DSSCs) were studied. The results revealed that Nb{sup 5+} doping replaces Ti{sup 4+} cations in TiO{sub 2} lattice, and the bandgap of the films varies with increasing Nb doping concentration because of the downshift of the conduction band minimum (CBM). The niobium-doped TiO{sub 2} DSSCs with moderate loadings show enhanced performance comparing with their pure TiO{sub 2} counterparts. Optimally, the conversion efficiency of the Nb-3.5 (Nb 3.5 mol%) DSSC is 4.99%. This is higher than that (4.39%) of pure TiO{sub 2} cells by 13.7%. This is due to the fact that the Nb-doped solar cells have increased the number of the photo-induced electrons because of their exposed (001) facets and higher specific surface area; and enhanced electrons collection and transport because of the downshifted CBM of the Nb-doped TiO{sub 2}. However, heavy Nb doping results in the decrease of the performance of the niobium-doped cells due to the excessive defects within the Nb-TiO{sub 2} samples resulting in enhanced charge recombination at defects.

3D Geological Modeling of CoalBed Methane (CBM) Resources in the Taldykuduk Block Karaganda Coal Basin, Kazakhstan

Science.gov (United States)

Sadykov, Raman; Kiponievich Ogay, Evgeniy; Royer, Jean-Jacques; Zhapbasbayev, Uzak; Panfilova, Irina

2015-04-01

Coal Bed Methane (CBM) is gas stored in coal layers. It can be extracted from wells after hydraulic fracturing and/or solvent injection, and secondary recovery techniques such as CO2 injection. Karaganda Basin is a very favorable candidate region to develop CBM production for the following reasons: (i) Huge gas potential; (ii) Available technologies for extracting and commercializing the gas produced by CBM methods; (iii) Experience in degassing during underground mining operations for safety reasons; (iv) Local needs in energy for producing electricity for the industrial and domestic market. The objectives of this work are to model the Taldykuduk block coal layers and their properties focusing on Coal Bed Methane production. It is motivated by the availability of large coal bed methane resources in Karaganda coal basin which includes 4 300 Bm3 equivalent 2 billion tons of coal (B = billion = 109) with gas content 15-25 m3/t of coal (for comparison San Juan basin (USA) has production in a double porosity model considering two domains: the matrix (m) and the fracture (f) for which the initial and boundary conditions are different. The resulting comprehensive 3D models had helped in better understanding the tectonic structures of the region, especially the relationships between the fault systems.

Macroeconomia do Turismo Argentino em Santa Catarina

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Roberto Meurer

2010-07-01

Full Text Available Resumo O Estado de Santa Catarina experimentou um considerável crescimento do setor de turismo nas últimas décadas. O fluxo turístico de origem argentina revelou-se um ingrediente importante dessa trajetória. Este artigo focaliza um aspecto pouco explorado, aparentemente, da participação argentina no turismo estadual: a relação entre a situação macroeconômica do país vizinho e a demanda turística por Santa Catarina lá originada. Começa-se abordando brevemente a problemática geral da macroeconomia do turismo. Depois, discorre-se sobre o crescimento desse setor em Santa Catarina, destacando a presença de argentinos. A terceira parte desenvolve uma análise baseada em tratamento estatístico de dados sobre demanda e receita geradas por esses turistas no estado, com exame das correlações envolvendo taxa de câmbio e taxa de crescimento do PIB da Argentina. Palavras-chave: turismo; Santa Catarina; turistas argentinos; economia argentina Abstract The State of Santa Catarina has witnessed a considerable development of its tourist sector in the last decades. The demand from Argentina has proved to be an important factor of that growth. This article deals with a feature of the presence of Argentinians in the state which seems to be scarcely studied: the relationship between the macroeconomic situation of Argentina and the tourist demand in Santa Catarina originated from that country. The first part of the article considers briefly the general issue of tourism macroeconomics. The second one looks upon tourism growth in Santa Catarina, stressing the presence of visitors from Argentine. The third section develops an analysis based on statistical treatment of data concerning demand and income generated by such tourists in Santa Catarina, involving correlations that consider aspects like exchange rate and the rate of GDP increase in Argentina. Keywords: tourism; Santa Catarina; tourists from Argentina; Argentina’s economy

O USO DA LÍNGUA INGLESA COMO FERRAMENTA DE ENSINO E APRENDIZAGEM NA EDUCAÇÃO AMBIENTAL: UMA EXPERIÊNCIA NA ESCOLA AGOSTINHA DILL- CONDOR, RS

OpenAIRE

Mello, Alexandra Freitas de; Peres, Paulo Edelvar Corrêa

2011-01-01

This paper presents the main results of the Specialization Monograph of the Sensu Lato Post graduate Course on Environmental Education, edition held in 2008 and 2009 by Federal University of Santa Maria in Panambi. This paper aims to use the English language as a tool for sensitization and changes in attitudes in the teaching of environmental education with students from Escola Estadual de Ensino Médio Agostinha Dill Condor/RS, using playful tools, games and activities, to promote environment...

CBM Maze-Scores as Indicators of Reading Level and Growth for Seventh-Grade Students

Science.gov (United States)

Chung, Siuman; Espin, Christine A.; Stevenson, Claire E.

2018-01-01

The technical adequacy of CBM maze-scores as indicators of reading level and growth for seventh-grade secondary-school students was examined. Participants were 452 Dutch students who completed weekly maze measures over a period of 23 weeks. Criterion measures were school level, dyslexia status, scores and growth on a standardized reading test.…

The Alignment of easyCBM[R] Math Measures to Curriculum Standards. Technical Report #1002

Science.gov (United States)

Nese, Joseph F. T.; Lai, Cheng-Fei; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald; Alonzo, Julie

2010-01-01

The purpose of this study was to examine the alignment of the easyCBM[R] mathematics benchmark and progress monitoring measures to the National Council of Teachers of Mathematics "Curriculum Focal Points" (NCTM, 2006). Based on Webb's alignment model (1997, 2002), we collected expert judgments on individual math items across a sampling of forms…

Harold A. Hyde: Recollections of Santa Cruz County

OpenAIRE

Hyde, Harold A.; Jarrell, Randall; Regional History Project, UCSC Library

2002-01-01

A fifth-generation Santa Cruz County resident, Hyde has been in on the creation of organizations and institutions ranging from UCSC and Cabrillo College to the Community Foundation and the Cultural Council of Santa Cruz County. His contributions to California and Santa Cruz are documented in his oral history. Following infantry combat service with the U.S. Army in Europe during World War II and graduate studies in business at Harvard, Hyde returned to Santa Cruz County and a career a...

Concept and design of an alignment monitoring system for the CBM RICH mirrors

Energy Technology Data Exchange (ETDEWEB)

Bendarouach, Jordan [Justus Liebig University (Germany); Collaboration: CBM-Collaboration

2016-07-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR (Facility for Antiproton and Ion Research) complex will investigate the phase diagram of strongly interacting matter at high baryon density and moderate temperatures in A+A collisions from 2-11 AGeV (SIS100) beam energy. One of the key detector components required for this CBM physics program is the RICH (Ring Imaging CHerenkov) detector, developed for efficient and clean electron identification and pion suppression. The detector consists of about 80 spherical glass mirror tiles, distributed over two sphere parts. An important aspect to guarantee a stable operation of the RICH detector is the alignment of the mirrors. A method originally developed and inspired by the HERA-B experiment uses recorded data to assess mirror alignment of the RICH mirror system. Measurements of Cherenkov distances and angles on the PMT plane may reveal potential misalignments of the considered tile. If mirror misalignment is revealed, it can be subsequently included and rectified by correction routines, which should mostly increase ring reconstruction as well as ring-track matching efficiencies. Results of this alignment method based on simulated events, reproducing potential mirror misalignments, its limits and first correction routines are presented.

Development of a transition radiation detector and reconstruction of photon conversions in the CBM experiment

International Nuclear Information System (INIS)

Klein-Boesing, Melanie

2009-01-01

The focus of this thesis is the development of a Transition Radiation Detector (TRD) for the Compressed Baryonic Matter (CBM) experiment at the future Facility for Antiproton and Ion Research (FAIR) in Darmstadt. In addition, the usage of the TRD in the measurement of direct photons is investigated. CBM will be a fixed-target heavy-ion experiment, which investigates collisions in the beam energy range of 5-35 AGeV and aims to investigate the regime of high baryon densities where the phase transition is expected to be of first order. It will be a multipurpose experiment with the ability to measure leptons, hadrons, and photons. Therein, a TRD will provide the electron identification and - together with a Silicon Tracking System (STS) - the tracking of charged particles. In conjunction with a ring imaging Cherenkov (RICH) detector and a time-of-flight (TOF) measurement, the TRD is to provide a sufficient electron identification for the measurements of charmonium and low-mass vector mesons. For the TRD, the required pion suppression is a factor of about 100 at 90% electron efficiency, and the position resolution has to be of the order of 300 to 500 um. Moreover, the material budget in terms of radiation length has to be kept at a minimum in order to minimize multiple scattering and conversions which would limit the precise measurement in following TRD stations and other detectors. The largest and up to now unrivaled challenge for the TRD design is that both (PID and tracking) have to be fulfilled in the context of very high particle rates (event rates of up to 10MHz are envisaged) and at the same time large charged-particle multiplicities of up to 600 per event in the CBM detector acceptance. Small prototypes of the TRD based on multiwire proportional chambers (MWPC) with pad readout were developed and tested. The tracking performance and the electron-pion separation were determined for particle rates of up to 200 kHz/cm 2 . The TRD layout and the detector responses

Development of a transition radiation detector and reconstruction of photon conversions in the CBM experiment

Energy Technology Data Exchange (ETDEWEB)

Klein-Boesing, Melanie

2009-07-01

The focus of this thesis is the development of a Transition Radiation Detector (TRD) for the Compressed Baryonic Matter (CBM) experiment at the future Facility for Antiproton and Ion Research (FAIR) in Darmstadt. In addition, the usage of the TRD in the measurement of direct photons is investigated. CBM will be a fixed-target heavy-ion experiment, which investigates collisions in the beam energy range of 5-35 AGeV and aims to investigate the regime of high baryon densities where the phase transition is expected to be of first order. It will be a multipurpose experiment with the ability to measure leptons, hadrons, and photons. Therein, a TRD will provide the electron identification and - together with a Silicon Tracking System (STS) - the tracking of charged particles. In conjunction with a ring imaging Cherenkov (RICH) detector and a time-of-flight (TOF) measurement, the TRD is to provide a sufficient electron identification for the measurements of charmonium and low-mass vector mesons. For the TRD, the required pion suppression is a factor of about 100 at 90% electron efficiency, and the position resolution has to be of the order of 300 to 500 um. Moreover, the material budget in terms of radiation length has to be kept at a minimum in order to minimize multiple scattering and conversions which would limit the precise measurement in following TRD stations and other detectors. The largest and up to now unrivaled challenge for the TRD design is that both (PID and tracking) have to be fulfilled in the context of very high particle rates (event rates of up to 10MHz are envisaged) and at the same time large charged-particle multiplicities of up to 600 per event in the CBM detector acceptance. Small prototypes of the TRD based on multiwire proportional chambers (MWPC) with pad readout were developed and tested. The tracking performance and the electron-pion separation were determined for particle rates of up to 200 kHz/cm{sup 2}. The TRD layout and the detector

TERT-CLPTM1 locus polymorphism (rs401681 is associated with the prognosis of hepatocellular carcinoma

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Lee HW

2017-10-01

Full Text Available Hye Won Lee,1,* Won-Jin Park,2,* Yu-Ran Heo,2 Tae In Park,3 Soo Young Park,4 Jae-Ho Lee2,* 1Department of Pathology, Keimyung University School of Medicine, Daegu, Republic of Korea; 2Department of Anatomy, Keimyung University School of Medicine, Daegu, Republic of Korea; 3Department of Pathology, Kyungpook National University School of Medicine, Daegu, Republic of Korea; 4Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea *These authors contributed equally to this work Abstract: Telomere length is associated with the development of hepatocellular carcinoma (HCC, and recent studies have focused on the genetic alteration or polymorphism in telomere-maintaining genes. We examined the clinicopathologic and prognostic value of rs401681 polymorphism, located in the TERT-CLPTM1L locus, in HCC. The relationship between rs401681 variants and telomere length was also analyzed in 156 HCC patients. The rs401681 polymorphism had the following genotype frequencies: C/C in 51.3% of the samples, C/T in 39.7%, and T/T in 9.0%. Telomeres in the tumor samples were 4.04-fold longer, on average, than the telomeres in matched normal samples (SD =1.32, and there were no differences in telomere length according to rs401681 polymorphism (p=0.802. Our results indicate that the rs401681 C allele was significantly associated with increased T and International Union for Cancer Control stages (p<0.01. Univariate and multivariate survival analyses showed that HCC with C allele had poorer prognosis (p<0.01. In conclusion, our findings suggest that rs401681 is a possible prognostic biomarker for HCC patients. Keywords: CLPTM1L polymorphism, hepatocellular carcinoma, TERT-CLPTM1L locus, telomere length

Association of STAT4 rs7574865 polymorphism with susceptibility to inflammatory bowel disease: A systematic review and meta-analysis.

Science.gov (United States)

Liu, Qi-Fei; Li, Yi; Zhao, Qi-Hong; Wang, Zheng-Yu; Hu, Shuang; Yang, Chao-Qun; Ye, Kui; Li, Li

2015-10-01

Association of Signal transducers and activators of transcription-4 (STAT4) gene polymorphism with susceptibility to inflammatory bowel disease have been investigated in a number of epidemiological studies, but the results are inclusive. The aim of this meta-analysis was to more precisely estimate the relationship. The databases of Pubmed and CBM updated to October, 2014 were retrieved. Random- or fixed-effect model was used to estimate odd radio (OR) and corresponding 95% confidence interval (95%CI) on the basis of heterogeneity. Seven articles containing 2196 Crohn's disease (CD) cases, 1588 ulcerative colitis (UC) cases and 4126 controls were identified. We detected a significant association between STAT4 rs7574865 polymorphism and IBD susceptibility in overall population (GG vs. GT+TT, OR=0.855, 95% CI=0.760-0.962, P=0.009), but not in Caucasian and Asian population, respectively. No association was detected between rs7574865 polymorphism and CD susceptibility in overall, Asian and Caucasian population, respectively. Interestingly, a significant association was detected between rs7574865 with UC susceptibility in overall population (G vs. T, OR=0.881, 95% CI=0.798-0.972, P=0.012; GG vs. GT+TT, OR=0.788, 95% CI=0.679-0.914, P=0.002; GG vs. TT, OR=0.683, 95% CI=0.498-0.937, P=0.018) and Caucasians (GG vs. GT+TT, OR=0.833, 95% CI=0.701-0.990, P=0.038; GG+GT vs. TT, OR=0.667, 95% CI=0.456-0.975, P=0.037; GG vs. TT, OR=0.636, 95% CI=0.433-0.934, P=0.021), respectively, and a possible association was found in Asian population (GG vs. GT+TT, OR=0.709, 95% CI=0.503-0.998, P=0.049). STAT4 rs7574865 gene is IBD risk factor, and this gene polymorphism is associated with UC susceptibility, especially in Caucasians. To confirm these findings, further studies with more sample size are required for a definitive conclusion. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Effect of rs1344706 in the ZNF804A gene on the brain network

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Xiongying Chen

2018-01-01

Full Text Available ZNF804A rs1344706 (A/C was the first SNP that reached genome-wide significance for schizophrenia. Recent studies have linked rs1344706 to functional connectivity among specific brain regions. However, no study thus far has examined the role of this SNP in the entire functional connectome. In this study, we used degree centrality to test the role of rs1344706 in the whole-brain voxel-wise functional connectome during the resting state. 52 schizophrenia patients and 128 healthy controls were included in the final analysis. In our whole-brain analysis, we found a significant interaction effect of genotype × diagnosis at the precuneus (PCU (cluster size = 52 voxels, peak voxel MNI coordinates: x = 9, y = −69, z = 63, F = 32.57, FWE corrected P < 0.001. When we subdivided the degree centrality network according to anatomical distance, the whole-brain analysis also found a significant interaction effect of genotype × diagnosis at the PCU with the same peak in the short-range degree centrality network (cluster size = 72 voxels, F = 37.29, FWE corrected P < 0.001. No significant result was found in the long-range degree centrality network. Our results elucidated the contribution of rs1344706 to functional connectivity within the brain network, and may have important implications for our understanding of this risk gene's role in functional dysconnectivity in schizophrenia.

The joint effect of the endothelin receptor B gene (EDNRB polymorphism rs10507875 and nitric oxide synthase 3 gene (NOS3 polymorphism rs869109213 in Slovenian patients with type 2 diabetes mellitus and diabetic retinopathy

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Dejan Bregar

2018-02-01

Full Text Available Increasing evidence suggests that endothelin and nitric oxide synthase genes and their products exert biological effects on the vasculature via the nitric oxide or endothelin pathway. The aim of the study was to evaluate the association of rs10507875 and rs869109213 (alone or in interaction with diabetic retinopathy (DR in subjects with type 2 diabetes mellitus (T2DM. We genotyped the single nucleotide polymorphism rs10507875 of the endothelin receptor B gene (EDNRB and variable number tandem repeats rs869109213 of the nitric oxide synthase 3 gene (NOS3 in 270 Slovenian patients with DR and T2DM and 256 controls with T2DM without clinical signs of DR. The genotyping was performed using either real-time polymerase chain reaction (PCR or standard PCR. We found a significant association between the genotypes of NOS3 rs869109213 polymorphism and the risk of DR in the co-dominant model (4a4b genotype; 1.99-fold increased risk [1.09-3.65]; 95% confidence interval [CI]; p = 0.02, co-dominant model (4a4a genotype; 4.16-fold increased risk [1.03-16.74]; 95% CI; p = 0.04, and dominant model (4a4a and 4a4b genotypes; 2.22-fold increased risk [1.26-3.92]; 95% CI; p = 0.01 compared to the 4b4b genotype. Moreover, the joint effect of the two polymorphisms on DR risk was greater than the individual effect of each polymorphism in the analyzed genetic models. Additionally, adjusted odds ratio showed an increased risk in dominant × dominant (4.15-fold [1.40-12.26]; 95% CI; p = 0.01 and recessive × dominant (2.24-fold [1.25-4.01]; 95% CI; p = 0.02 genotype combinations of the two polymorphisms. In conclusion, our results indicate that NOS3 rs869109213 polymorphism alone or in a combination with EDNRB rs10507875 polymorphism may be associated with DR in Slovenian patients with T2DM.

Characterization of silicon microstrip sensors, front-end electronics, and prototype tracking detectors for the CBM experiment at FAIR

Energy Technology Data Exchange (ETDEWEB)

Sorokin, Iurii

2013-07-01

The Compressed Baryonic Matter (CBM) experiment will explore the phase diagram of strongly interacting matter in the region of high net baryonic densities. The matter at the extreme conditions will be studied in collisions of a heavy ion beam with a fixed heavy element target. The present work is devoted to the development of the main component of the CBM experiment - the Silicon Tracking System (STS). The STS has to enable reconstruction of up to 1000 charged particle tracks per nucleus-nucleus interaction at the rate of up to 10 MHz, provide a momentum resolution Δp/p of 1 %, and withstand the radiation load of up to 10{sup 14} n{sub eq}/cm{sup 2} (n{sub eq}-neutron equivalent). The STS will be based on double-sided silicon microstrip sensors, that will be arranged in 8 planes in the aperture of the dipole magnet. Selftriggering readout electronics will be located on the periphery of the detecting planes, and connected to the sensors with low mass microcables. In the stage of R and D, as well as in the stages of pre-series and series production, characterization of the sensors, of the front-end electronics, and of the complete detector modules has to be performed. In the present work the required techniques were developed, and the performance of the latest detector prototypes was evaluated. A particular attention is paid to evaluation of the signal amplitude, as it is one of the most important detector characteristics. Techniques for measuring the passive electrical characteristics of the sensors were developed. These include: the coupling and the interstrip capacitances, the interstrip resistance, the bias resistance, the strip leakage current, the bulk capacitance, and the bulk leakage current. The techniques will be applied for the quality assurance of the sensors during the pre-series and the series production. Extensive characterization of the prototype readout chip, n-XYTER, was performed. The register settings were optimized, and the dependence of the

RS CVn binary systems

International Nuclear Information System (INIS)

Linsky, J.L.

1984-01-01

The author attempts to place in context the vast amount of data obtained in the last few years as a result of X-ray, ultraviolet, optical, and microwave observations of RS CVn and similar spectroscopic binary systems. He concentrates on the RS CVn systems and their long-period analogs, and restricts the scope by attempting to answer on the basis of the recent data and theory following questions: (1) Are the original defining characteristics still valid and still adequate? (2) What is the evidence for discrete active regions? (3) Have we derived any meaningful physical properties for the atmospheres of RS CVn systems? (4) What are the flare observations telling us about magnetic fields in the RS CVn systems? (5) Is there evidence for systematic trends in RS CVn systems with spectral type?

RS-WebPredictor

DEFF Research Database (Denmark)

Zaretzki, J.; Bergeron, C.; Huang, T.-W.

2013-01-01

Regioselectivity-WebPredictor (RS-WebPredictor) is a server that predicts isozyme-specific cytochrome P450 (CYP)-mediated sites of metabolism (SOMs) on drug-like molecules. Predictions may be made for the promiscuous 2C9, 2D6 and 3A4 CYP isozymes, as well as CYPs 1A2, 2A6, 2B6, 2C8, 2C19 and 2E1....... RS-WebPredictor is the first freely accessible server that predicts the regioselectivity of the last six isozymes. Server execution time is fast, taking on average 2s to encode a submitted molecule and 1s to apply a given model, allowing for high-throughput use in lead optimization projects.......Availability: RS-WebPredictor is accessible for free use at http://reccr.chem.rpi.edu/ Software/RS-WebPredictor....

A systematic review and summarization of the recommendations and research surrounding Curriculum-Based Measurement of oral reading fluency (CBM-R) decision rules.

Science.gov (United States)

Ardoin, Scott P; Christ, Theodore J; Morena, Laura S; Cormier, Damien C; Klingbeil, David A

2013-02-01

Research and policy have established that data are necessary to guide decisions within education. Many of these decisions are made within problem solving and response to intervention frameworks for service delivery. Curriculum-Based Measurement in Reading (CBM-R) is a widely used data collection procedure within those models of service delivery. Although the evidence for CBM-R as a screening and benchmarking procedure has been summarized multiple times in the literature, there is no comprehensive review of the evidence for its application to monitor and evaluate individual student progress. The purpose of this study was to identify and summarize the psychometric and empirical evidence for CBM-R as it is used to monitor and evaluate student progress. There was an emphasis on the recommended number of data points collected during progress monitoring and interpretive guidelines. The review identified 171 journal articles, chapters, and instructional manuals using online search engines and research databases. Recommendations and evidence from 102 documents that met the study criteria were evaluated and summarized. Results indicate that most decision-making practices are based on expert opinion and that there is very limited psychometric or empirical support for such practices. There is a lack of published evidence to support program evaluation and progress monitoring with CBM-R. More research is required to inform data collection procedures and interpretive guidelines. Copyright © 2012 Society for the Study of School Psychology. Published by Elsevier Ltd. All rights reserved.

Atributos microbianos e químicos do solo em sistemas de produção convencional e orgânico de maçãs no estado de Santa Catarina Microbiological and chemical soil attributes in apple orchards under conventional and organic production systems in th State of Santa Catarina, Brazil

Directory of Open Access Journals (Sweden)

Carolina Riviera Duarte Maluche-Baretta

2007-08-01

Full Text Available O estudo foi realizado no município de Urupema-SC, com o objetivo de avaliar os efeitos dos sistemas de produção convencional e orgânico de maçãs sobre a biomassa microbiana do solo, sua atividade e as relações com o C e o N do solo. Foram feitas amostragens de solo junto à copa de 24 plantas distribuídas em uma grade de 45 x 54 m em pomares submetidos aos dois sistemas de produção, na profundidade de 0-10 cm, nos períodos de dezembro/2002 e junho/2003, para quantificação de teores de C da biomassa microbiana (CBM, C orgânico total do solo (COT, N da biomassa microbiana (NBM, N total do solo (NT, respiração basal (C-CO2 e obtenção das relações CBM:COT, NBM:NT e quociente metabólico (qCO2. O pomar orgânico (PO apresentou, nas duas épocas de amostragem, os maiores teores de CBM, COT e a maior relação CBM:COT, comparado ao pomar convencional (PC. Os atributos NBM e NT e a relação NBM:NT mostraram-se menos sensíveis às mudanças ocasionadas pelos sistemas de manejo dos pomares e épocas de amostragem. O C-CO2 não apresentou diferença entre tratamentos, sendo apenas significativo quanto à época de amostragem, enquanto para o qCO2 os maiores valores encontrados foram no PC.The study was carried out in Urupema, state of Santa Catarina, to evaluate the effects of conventional and organic apple production systems on soil microbial biomass, soil microbial activity and the relationship between soil microbial biomass attributes and C and N soil contents. The soil under the canopy of 24 plants (0-10 cm was sampled in a 45 x 54 m grid, in both orchards (conventional and organic, in December 2002 and June 2003, and analyzed for: microbial biomass carbon (MBC, total organic carbon (TOC, microbial biomass nitrogen (MBN, total nitrogen (TN, basal respiration (C-CO2, MBC:TOC and MBN:TN ratios, and metabolic quotient (qCO2. The values of MBC, TOC, and MBC:TOC ratio were higher in the organic than in the conventional orchard on

Toxicology in the 21st century - Working our way towards a visionary reality

NARCIS (Netherlands)

Berg, N.; Wever, B.de; Fuchs, H.W.; Gaca, M.; Krul, C.A.M.; Roggen, E.L.

2011-01-01

In November 2009 the In Vitro Testing Industrial Platform (IVTIP) organized a meeting entitled '. Toxicology in the 21st century - working our way towards a visionary reality'. Participating delegates included scientists, key opinion leaders, developers and users of 3Rs-related tests and testing

Conception and design of a control and monitoring system for the mirror alignment of the CBM RICH detector

Science.gov (United States)

Bendarouach, J.

2016-08-01

The Compressed Baryonic Matter (CBM) experiment at the future Facility for Anti-proton and Ion Research (FAIR) complex will investigate the phase diagram of strongly interacting matter at high baryon density and moderate temperatures created in A+A collisions. For the SIS100 accelerator, the foreseen beam energy will range up to 11 AGeV for the heaviest nuclei. One of the key detector components required for the CBM physics program is the Ring Imaging CHerenkov (RICH) detector, which is developed for efficient and clean electron identification and pion suppression. An important aspect to guarantee a stable operation of the RICH detector is the alignment of the mirrors. A qualitative alignment control procedure for the mirror system has been implemented in the CBM RICH prototype detector and tested under real conditions at the CERN PS/T9 beamline. Collected data and results of image processing are reviewed and discussed. In parallel a quantitative method using recorded data has also been employed to compute mirror displacements of the RICH mirrors. Results based on simulated events and the limits of the method are presented and discussed as well. If mirror misalignment is detected, it can be subsequently included and rectified by correction routines. A first correction routine is presented and a comparison between misaligned, corrected and ideal geometries is shown.

Conception and design of a control and monitoring system for the mirror alignment of the CBM RICH detector

International Nuclear Information System (INIS)

Bendarouach, J

2016-01-01

The Compressed Baryonic Matter (CBM) experiment at the future Facility for Anti-proton and Ion Research (FAIR) complex will investigate the phase diagram of strongly interacting matter at high baryon density and moderate temperatures created in A+A collisions. For the SIS100 accelerator, the foreseen beam energy will range up to 11 AGeV for the heaviest nuclei. One of the key detector components required for the CBM physics program is the Ring Imaging CHerenkov (RICH) detector, which is developed for efficient and clean electron identification and pion suppression. An important aspect to guarantee a stable operation of the RICH detector is the alignment of the mirrors. A qualitative alignment control procedure for the mirror system has been implemented in the CBM RICH prototype detector and tested under real conditions at the CERN PS/T9 beamline. Collected data and results of image processing are reviewed and discussed. In parallel a quantitative method using recorded data has also been employed to compute mirror displacements of the RICH mirrors. Results based on simulated events and the limits of the method are presented and discussed as well. If mirror misalignment is detected, it can be subsequently included and rectified by correction routines. A first correction routine is presented and a comparison between misaligned, corrected and ideal geometries is shown. (paper)

Association between ACE (rs4646994), FABP2 (rs1799883), MTHFR (rs1801133), FTO (rs9939609) Genes Polymorphism and Type 2 Diabetes with Dyslipidemia.

Science.gov (United States)

Raza, Syed Tasleem; Abbas, Shania; Siddiqi, Zeba; Mahdi, Farzana

2017-01-01

Diabetic dyslipidemia is one of the leading causes of coronary artery disease (CAD) death. Genetic and environmental factors play an important role in the development of type 2 diabetes mellitus (T2DM) and dyslipidemia. The present study was aimed to investigate the association of ACE (rs4646994), FABP2 (rs1799883), MTHFR (rs1801133) and FTO (rs9939609) genes polymorphism in T2DM with dyslipidemia. Totally, 559 subjects including 221 T2DM cases with dyslipidemia, 158 T2DM without dyslipidemia and 180 controls were enrolled. ACE genes polymorphism was evaluated by polymerase chain reaction (PCR), while MTHFR , FABP2 , FTO genes polymorphisms were evaluated by PCR and restriction fragment length polymorphism (RFLP). Significant association of ACE and MTHFR genes polymorphisms were found in both group of cases [T2DM with dyslipidemia (Pgenes polymorphisms were significantly associated with T2DM without dyslipidemia (P=0.038, and P= 0.019, respectively). This study concludes that ACE , FABP2 , FTO and MTHFR genes are associated with T2DM. Additionally, it also seems that ACE and MTHFR genes might be further associated with the development of dyslipidemia in T2DM cases.

CBM progress report 2007

Energy Technology Data Exchange (ETDEWEB)

Herrmann, N.; Rami, F.; Roehrich, D.; Stroth, J.; Wessels, J.; Zaitsev, Yu

2008-02-15

This report documents the activities within the CBM project in 2007. Significant progress has been made in the optimization of the simulation software, the layout and development of detectors, the design of front-end electronics, and the concepts for data acquisition. The simulation and analysis routines have been completely integrated into the software framework (FAIRoot and CBMroot), and can be used now easily by users outside GSI. A breakthrough has been achieved in the development of fast algorithms for track and vertex reconstruction which have been improved in speed by a factor of 10{sup 5}. These fast routines permit to perform high-statistics simulations for detailed detector layout optimization. Full event reconstruction based on realistic detector properties and particle multiplicities as given by microscopic transport models are routinely used in the feasibility studies. A version of the Silicon Tracking System is now implemented in the simulation software comprising 8 detector layers based on microstrip technology only, including the readout cables, and the mechanical detector structure. The studies of open charm detection have been extended to D{sub s}{sup +} and {lambda}{sub c}, taking into account a realistic layout of the Silicon Pixel Microvertex detector. The identification of electrons has been optimized by improved ring recognition algorithms and transition radiation simulations. The Ring Imaging Cherenkov (RICH) detector has been redesigned, resulting in a reduction by a factor of two in mirror size and number of readout channels without reducing the pion rejection capability. The muon detection system has been optimized with respect to the number of detector layers. The muon simulations take into account detector inefficiencies and a segmentation of the muon chambers into pads according to a nominal occupancy of 5% for central Au+Au collisions. Studies for a dimuon trigger show promising results. Radiation dose simulations using the FLUKA

CBM progress report 2007

International Nuclear Information System (INIS)

Herrmann, N.; Rami, F.; Roehrich, D.; Stroth, J.; Wessels, J.; Zaitsev, Yu

2008-02-01

This report documents the activities within the CBM project in 2007. Significant progress has been made in the optimization of the simulation software, the layout and development of detectors, the design of front-end electronics, and the concepts for data acquisition. The simulation and analysis routines have been completely integrated into the software framework (FAIRoot and CBMroot), and can be used now easily by users outside GSI. A breakthrough has been achieved in the development of fast algorithms for track and vertex reconstruction which have been improved in speed by a factor of 10 5 . These fast routines permit to perform high-statistics simulations for detailed detector layout optimization. Full event reconstruction based on realistic detector properties and particle multiplicities as given by microscopic transport models are routinely used in the feasibility studies. A version of the Silicon Tracking System is now implemented in the simulation software comprising 8 detector layers based on microstrip technology only, including the readout cables, and the mechanical detector structure. The studies of open charm detection have been extended to D s + and Λ c , taking into account a realistic layout of the Silicon Pixel Microvertex detector. The identification of electrons has been optimized by improved ring recognition algorithms and transition radiation simulations. The Ring Imaging Cherenkov (RICH) detector has been redesigned, resulting in a reduction by a factor of two in mirror size and number of readout channels without reducing the pion rejection capability. The muon detection system has been optimized with respect to the number of detector layers. The muon simulations take into account detector inefficiencies and a segmentation of the muon chambers into pads according to a nominal occupancy of 5% for central Au+Au collisions. Studies for a dimuon trigger show promising results. Radiation dose simulations using the FLUKA transport code have been

Analyzing the Reliability of the easyCBM Reading Comprehension Measures: Grade 2. Technical Report #1201

Science.gov (United States)

Lai, Cheng-Fei; Irvin, P. Shawn; Alonzo, Julie; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we present the results of a reliability study of the second-grade multiple choice reading comprehension measures available on the easyCBM learning system conducted in the spring of 2011. Analyses include split-half reliability, alternate form reliability, person and item reliability as derived from Rasch analysis,…

Analyzing the Reliability of the easyCBM Reading Comprehension Measures: Grade 3. Technical Report #1202

Science.gov (United States)

Lai, Cheng-Fei; Irvin, P. Shawn; Park, Bitnara Jasmine; Alonzo, Julie; Tindal, Gerald

2012-01-01

In this technical report, we present the results of a reliability study of the third-grade multiple choice reading comprehension measures available on the easyCBM learning system conducted in the spring of 2011. Analyses include split-half reliability, alternate form reliability, person and item reliability as derived from Rasch analysis,…

Analyzing the Reliability of the easyCBM Reading Comprehension Measures: Grade 5. Technical Report #1204

Science.gov (United States)

Park, Bitnara Jasmine; Irvin, P. Shawn; Lai, Cheng-Fei; Alonzo, Julie; Tindal, Gerald

2012-01-01

In this technical report, we present the results of a reliability study of the fifth-grade multiple choice reading comprehension measures available on the easyCBM learning system conducted in the spring of 2011. Analyses include split-half reliability, alternate form reliability, person and item reliability as derived from Rasch analysis,…

Analyzing the Reliability of the easyCBM Reading Comprehension Measures: Grade 4. Technical Report #1203

Science.gov (United States)

Park, Bitnara Jasmine; Irvin, P. Shawn; Alonzo, Julie; Lai, Cheng-Fei; Tindal, Gerald

2012-01-01

In this technical report, we present the results of a reliability study of the fourth-grade multiple choice reading comprehension measures available on the easyCBM learning system conducted in the spring of 2011. Analyses include split-half reliability, alternate form reliability, person and item reliability as derived from Rasch analysis,…

Analyzing the Reliability of the easyCBM Reading Comprehension Measures: Grade 6. Technical Report #1205

Science.gov (United States)

Irvin, P. Shawn; Alonzo, Julie; Park, Bitnara Jasmine; Lai, Cheng-Fei; Tindal, Gerald

2012-01-01

In this technical report, we present the results of a reliability study of the sixth-grade multiple choice reading comprehension measures available on the easyCBM learning system conducted in the spring of 2011. Analyses include split-half reliability, alternate form reliability, person and item reliability as derived from Rasch analysis,…

Analyzing the Reliability of the easyCBM Reading Comprehension Measures: Grade 7. Technical Report #1206

Science.gov (United States)

Irvin, P. Shawn; Alonzo, Julie; Lai, Cheng-Fei; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we present the results of a reliability study of the seventh-grade multiple choice reading comprehension measures available on the easyCBM learning system conducted in the spring of 2011. Analyses include split-half reliability, alternate form reliability, person and item reliability as derived from Rasch analysis,…

Santa Rosa de Lima: uma santa anoréxica na América Latina? Santa Rosa de Lima: ¿una santa anoréxica en Latinoamérica? Saint Rose of Lima: an anorexic saint in Latin America?

Directory of Open Access Journals (Sweden)

Cybelle Weinberg

2005-04-01

Full Text Available A literatura especializada tem nos mostrado que é grande a semelhança entre o comportamento alimentar das santas jejuadoras medievais e o das anoréxicas atuais. No entanto, há poucas referências sobre a existência de santas jejuadoras na América Latina. No presente trabalho, os autores salientam aspectos da vida de Santa Rosa de Lima, Patrona da América e Filipinas, que poderiam ser descritos como comportamentos anoréxicos. Comparando os aspectos psicopatológicos da vida de Santa Rosa com o comportamento das anoréxicas atuais, pareceu confirmar-se um padrão uniforme de comportamento, especialmente quanto ao aspecto imitativo, fator que poderia levar as jovens da atualidade a desenvolverem um transtorno alimentar após terem algum tipo de informação sobre o transtorno.La literatura especializada nos muestra gran similitud entre el comportamiento alimentar de las santas de la edad media que ayunaban y el de las anoréxicas de la actualidad. Hay pocas informaciones sobre santas que practicaban ayuno en Latinoamérica. En este artículo, los autores resaltan aspectos de la vida de santa Rosa de Lima, Patrona de América y Filipinas, que pueden ser considerados como comportamientos anoréxicos. Al comparar aspectos psicopatológicos de la vida de santa Rosa con el comportamiento de anoréxicas de la actualidad, parece que se confirma un modelo uniforme de comportamiento, especialmente respecto al aspecto de imitación, hecho que podría llevar a las jóvenes de hoy a desarrollar un trastorno de la alimentación luego de recibir informaciones sobre el tema.The specialized literature has shown us the great similarity between the eating habits of medieval fasting women saints and today's anorexic women. Nonetheless, there are few references to the existence of such fasting women saints in Latin America. The authors of this paper present some aspects of the life of Saint Rose of Lima, the patroness of the Americas and the Philippines, that

Association of the C-Reactive Protein Gene (CRP rs1205 C>T Polymorphism with Aortic Valve Calcification in Patients with Aortic Stenosis

Directory of Open Access Journals (Sweden)

Ewa Wypasek

2015-10-01

Full Text Available Elevation in C-reactive protein (CRP levels have been shown in patients with aortic valve stenosis (AS. Minor allele of the CRP gene (CRP rs1205 C>T polymorphism has been associated with lower plasma CRP concentrations in cohorts of healthy and atherosclerotic patients. Considering the existing similarities between atherosclerosis and AS, we examined the effect of CRP rs1205 C>T polymorphism on the AS severity. Three hundred consecutive Caucasian patients diagnosed with AS were genotyped for the rs1205 C>T polymorphism using the TaqMan assay. Severity of the AS was assessed using transthoracic echocardiography. The degree of calcification was analyzed semi-quantitatively. Carriers of the rs1205 T allele were characterized by elevated serum CRP levels (2.53 (1.51–3.96 vs. 1.68 (0.98–2.90 mg/L, p < 0.001 and a higher proportion of the severe aortic valve calcification (70.4% vs. 55.1%, p = 0.01 compared with major homozygotes. The effect of CRP rs1205 polymorphism on CRP levels is opposite in AS-affected than in unaffected subjects, suggesting existence of a disease-specific molecular regulatory mechanism. Furthermore, rs1205 variant allele predisposes to larger aortic valve calcification, potentially being a novel genetic risk marker of disease progression.

Programa de promoción de salud para infantes preescolares de círculos infantiles Santa Clara

OpenAIRE

Quintero Fleites, Eva Josefina

2011-01-01

Con el objetivo de desarrollar un Programa de promoción de salud para infantes preescolares, se realizó una investigación de desarrollo en el área de promoción de salud, con el universo de 34 círculos infantiles del municipio Santa Clara. Las muestras fueron de dos círculos infantiles, tanto para el diagnóstico como para el estudio piloto, y de ocho círculos infantiles para la extensión de la experiencia (cinco experimentales y tres controles). Las etapas investigativas fueron: diagnóst...

Prostate Cancer Susceptibility Polymorphism rs2660753 Is Not Associated with Invasive Ovarian Cancer

DEFF Research Database (Denmark)

Amankwah, Ernest K; Kelemen, Linda E; Wang, Qinggang

2011-01-01

BACKGROUND: We previously reported an association between rs2660753, a prostate cancer susceptibility polymorphism, and invasive epithelial ovarian cancer (EOC; OR = 1.2, 95% CI=1.0-1.4, P(trend) = 0.01) that showed a stronger association with the serous histological subtype (OR = 1.3, 95% CI = 1...

You're a "What"? Santa Claus

Science.gov (United States)

Royster, Sara

2013-01-01

Professional Santas entertain children and adults during the holiday season at all types of events. They work at shopping malls or stores; entertain crowds at parades and tree lightings; and make appearances at holiday parties, charity events, and people's homes. Most Santas work during the Christmas holiday season, which usually lasts from late…

Extraction of moments of net-particle event-by-event fluctuations in the CBM experiment

Energy Technology Data Exchange (ETDEWEB)

Vovchenko, Volodymyr [Frankfurt Institute for Advanced Studies, Frankfurt am Main (Germany); Goethe University, Frankfurt am Main (Germany); Taras Shevchenko University, Kyiv (Ukraine); Kisel, Ivan [Frankfurt Institute for Advanced Studies, Frankfurt am Main (Germany); Goethe University, Frankfurt am Main (Germany); Collaboration: CBM-Collaboration

2016-07-01

The future CBM experiment at FAIR will employ high intensity beams and large acceptance detectors in order to study the properties of the strongly interacting matter produced in heavy-ion collisions at high baryon densities. The search for the conjectured critical point of QCD is one the important tasks. It is predicted from statistical physics that higher moments of event-by-event fluctuations are very sensitive to the proximity of the critical point. This argument is explicitly demonstrated with the van der Waals equation of state. Thus, it was suggested that higher moments of fluctuations of conserved charges can be used as probes for the critical behavior. The statistical convergence of cumulants of different order is explored. The extraction of scaled variance, skewness, and kurtosis of proton distribution from simulated UrQMD events is performed and the efficiency correction described by binomial distribution is accounted for. The validity of this correction is tested with different modelings of the CBM detector response: from binomial distribution with fluctuating event-by-event efficiency to a full-scale GEANT simulation. The obtained results indicate that a more elaborate efficiency correction is needed in order to accurately reconstruct moments of higher orders.

PARP-1 Variant Rs1136410 Confers Protection against Coronary Artery Disease in a Chinese Han Population: A Two-Stage Case-Control Study Involving 5643 Subjects

Directory of Open Access Journals (Sweden)

Xue-bin Wang

2017-11-01

Full Text Available Inhibition of poly(ADP-ribose polymerase (PARP may protect against coronary artery disease (CAD in animal models, and rs1136410, a non-synonymous single nucleotide polymorphism (SNP in PARP-1, has a potential impact on PARP activities in vitro. This two-stage case-control study, involving 2803 CAD patients and 2840 controls, aimed to investigate the associations of PARP-1 rs1136410 with CAD development, lipid levels, PARP activities, 8-hydroxy-2′-dexyguanosine (8-OHdG, and interleukin (IL-6 levels in a Chinese Han population. Assuming a recessive model, the variant genotype GG of SNP rs1136410 showed a significantly inverse association with CAD risk (adjusted odds ratio (OR = 0.73, P < 0.001, left main coronary artery (LMCA lesions (P = 0.003, vessel scores (P = 0.003, and modified Gensini scores (P < 0.001. There were significant correlations of SNP rs1136410 with higher levels of total cholesterol (TC and lower levels of high-density lipoprotein cholesterol (HDL-c. In gene-environment interaction analyses, participants with the variant genotype GG, but without smoking habit, type 2 diabetes mellitus, and hyperlipidemia, conferred an 84% (P < 0.001 decreased risk of CAD. The genotype-phenotype correlation analyses further supported the functional roles of SNP rs1136410 in decreasing PARP activities and 8-OHdG levels. Taken together, our data suggest that SNP rs1136410 may confer protection against CAD through modulation of PARP activities and gene-environment interactions in a Chinese Han population.

FAUNA DO SOLO EM ÁREAS COM Eucalyptus spp. E Pinus elliottii, SANTA MARIA, RS

Directory of Open Access Journals (Sweden)

Maria Izabel Jacques Soares

2000-10-01

Full Text Available Este trabalho, com início na primavera de 1996 e término no inverno de 1997, teve como objetivo realizar o levantamento populacional da fauna do solo em áreas com Eucalyptus spp. e Pinus elliottii, situadas no Campus da Universidade Federal de Santa Maria, Rio Grande do Sul, Brasil. Para a coleta do solo, utilizou-se um extrator, formando-se amostras em dez pontos, nas profundidades de 0-5, 5-10, 10-15 e de 15-20 cm, em cada estação do ano. Por meio deste estudo, pôde-se identificar alguns representantes dos Phylum Annelida e Arthropoda que participam do contexto fauna-solo-vegetação. O total de indivíduos, seu respectivo percentual e número de indivíduos por metro quadrado foram obtidos. Observou-se o predomínio do Phylum Arthropoda e, mais especificamente, da classe Insecta na área com Eucalyptus spp. e do Phylum Annelida na área com Pinus elliottii. A variável profundidade originou modelos matemáticos que explicam a distribuição populacional dentre as áreas estudadas. A variável estação do ano não apresentou uma diferença significativa. Não foi possível, portanto, estabelecer um modelo de distribuição populacional.

Epidemiological study of facial fractures at the Oral and Maxillofacial Surgery Service, Santa Casa de Misericordia Hospital Complex, Porto Alegre - RS - Brazil

OpenAIRE

Zamboni, Rodrigo Andrighetti; Wagner, João Carlos Birnfeld; Volkweis, Maurício Roth; Gerhardt, Eduardo Luis; Buchmann, Elissa Muller; Bavaresco, Caren Serra

2017-01-01

ABSTRACT Objectives: to investigate the incidence and etiology of face trauma with diagnosis of facial fracture treated at the Buccomaxillofacial Surgery and Traumatology Service of the Santa Casa de Misericórdia Hospital Complex in Porto Alegre. Methods: we conducted a cross-sectional, retrospective epidemiological study of 134 trauma victims with 153 facial fractures. Results: the male gender was the most affected (86.6%) and the incidence was higher in the age group from 21 to 30 yea...

Research on the Conductivity-Based Detection Principles of Bubbles in Two-Phase Flows and the Design of a Bubble Sensor for CBM Wells.

Science.gov (United States)

Wu, Chuan; Wen, Guojun; Han, Lei; Wu, Xiaoming

2016-09-17

The parameters of gas-liquid two-phase flow bubbles in field coalbed methane (CBM) wells are of great significance for analyzing coalbed methane output, judging faults in CBM wells, and developing gas drainage and extraction processes, which stimulates an urgent need for detecting bubble parameters for CBM wells in the field. However, existing bubble detectors cannot meet the requirements of the working environments of CBM wells. Therefore, this paper reports findings on the principles of measuring the flow pattern, velocity, and volume of two-phase flow bubbles based on conductivity, from which a new bubble sensor was designed. The structural parameters and other parameters of the sensor were then computed, the "water film phenomenon" produced by the sensor was analyzed, and the appropriate materials for making the sensor were tested and selected. After the sensor was successfully devised, laboratory tests and field tests were performed, and the test results indicated that the sensor was highly reliable and could detect the flow patterns of two-phase flows, as well as the quantities, velocities, and volumes of bubbles. With a velocity measurement error of ±5% and a volume measurement error of ±7%, the sensor can meet the requirements of field use. Finally, the characteristics and deficiencies of the bubble sensor are summarized based on an analysis of the measurement errors and a comparison of existing bubble-measuring devices and the designed sensor.

Research on the Conductivity-Based Detection Principles of Bubbles in Two-Phase Flows and the Design of a Bubble Sensor for CBM Wells

Directory of Open Access Journals (Sweden)

Chuan Wu

2016-09-01

Full Text Available The parameters of gas-liquid two-phase flow bubbles in field coalbed methane (CBM wells are of great significance for analyzing coalbed methane output, judging faults in CBM wells, and developing gas drainage and extraction processes, which stimulates an urgent need for detecting bubble parameters for CBM wells in the field. However, existing bubble detectors cannot meet the requirements of the working environments of CBM wells. Therefore, this paper reports findings on the principles of measuring the flow pattern, velocity, and volume of two-phase flow bubbles based on conductivity, from which a new bubble sensor was designed. The structural parameters and other parameters of the sensor were then computed, the “water film phenomenon” produced by the sensor was analyzed, and the appropriate materials for making the sensor were tested and selected. After the sensor was successfully devised, laboratory tests and field tests were performed, and the test results indicated that the sensor was highly reliable and could detect the flow patterns of two-phase flows, as well as the quantities, velocities, and volumes of bubbles. With a velocity measurement error of ±5% and a volume measurement error of ±7%, the sensor can meet the requirements of field use. Finally, the characteristics and deficiencies of the bubble sensor are summarized based on an analysis of the measurement errors and a comparison of existing bubble-measuring devices and the designed sensor.

Research on the Conductivity-Based Detection Principles of Bubbles in Two-Phase Flows and the Design of a Bubble Sensor for CBM Wells

Science.gov (United States)

Wu, Chuan; Wen, Guojun; Han, Lei; Wu, Xiaoming

2016-01-01

The parameters of gas-liquid two-phase flow bubbles in field coalbed methane (CBM) wells are of great significance for analyzing coalbed methane output, judging faults in CBM wells, and developing gas drainage and extraction processes, which stimulates an urgent need for detecting bubble parameters for CBM wells in the field. However, existing bubble detectors cannot meet the requirements of the working environments of CBM wells. Therefore, this paper reports findings on the principles of measuring the flow pattern, velocity, and volume of two-phase flow bubbles based on conductivity, from which a new bubble sensor was designed. The structural parameters and other parameters of the sensor were then computed, the “water film phenomenon” produced by the sensor was analyzed, and the appropriate materials for making the sensor were tested and selected. After the sensor was successfully devised, laboratory tests and field tests were performed, and the test results indicated that the sensor was highly reliable and could detect the flow patterns of two-phase flows, as well as the quantities, velocities, and volumes of bubbles. With a velocity measurement error of ±5% and a volume measurement error of ±7%, the sensor can meet the requirements of field use. Finally, the characteristics and deficiencies of the bubble sensor are summarized based on an analysis of the measurement errors and a comparison of existing bubble-measuring devices and the designed sensor. PMID:27649206

Local Normative Data on easyCBM[R] Reading and Mathematics: Fall 2009. Technical Report # 0918

Science.gov (United States)

Tindal, Gerald; Alonzo, Julie; Anderson, Daniel

2009-01-01

We developed equivalent, alternate forms of easyCBM[R] in reading (n=20 forms) and mathematics (n=13 forms) with different skills reflective of the National Reading Panel (NRP) and the National Council of Teachers of Mathematics (NCTM), respectively. We then took three forms to use as screening measures in the fall, winter, and spring so educators…

77 FR 45530 - Approval and Promulgation of Implementation Plans; New Mexico; Albuquerque/Bernalillo County...

Science.gov (United States)

2012-08-01

... purpose of an I/M program is to bring about effective repairs with real emission reductions. When this... addition of emissions inspections for 1998 and newer diesel vehicles less than 10,001 pounds and all... Quality Bureau, 1190 St. Francis Drive, Santa Fe, New Mexico. Albuquerque Environmental Health Department...

Integration of the Shuttle RMS/CBM Positioning Virtual Environment Simulation

Science.gov (United States)

Dumas, Joseph D.

1996-01-01

Constructing the International Space Station, or other structures, in space presents a number of problems. In particular, payload restrictions for the Space Shuttle and other launch mechanisms prohibit assembly of large space-based structures on Earth. Instead, a number of smaller modules must be boosted into orbit separately and then assembled to form the final structure. The assembly process is difficult, as docking interfaces such as Common Berthing Mechanisms (CBMS) must be precisely positioned relative to each other to be within the "capture envelope" (approximately +/- 1 inch and +/- 0.3 degrees from the nominal position) and attach properly. In the case of the Space Station, the docking mechanisms are to be positioned robotically by an astronaut using the 55-foot-long Remote Manipulator System (RMS) robot arm. Unfortunately, direct visual or video observation of the placement process is difficult or impossible in many scenarios. One method that has been tested for aligning the CBMs uses a boresighted camera mounted on one CBM to view a standard target on the opposing CBM. While this method might be sufficient to achieve proper positioning with considerable effort, it does not provide a high level of confidence that the mechanisms have been placed within capture range of each other. It also does nothing to address the risk of inadvertent contact between the CBMS, which could result in RMS control software errors. In general, constraining the operator to a single viewpoint with few, if any, depth cues makes the task much more difficult than it would be if the target could be viewed in three-dimensional space from various viewpoints. The actual work area could be viewed by an astronaut during EVA; however, it would be extremely impractical to have an astronaut control the RMS while spacewalking. On the other hand, a view of the RMS and CBMs to be positioned in a virtual environment aboard the Space Shuttle orbiter or Space Station could provide similar benefits

The Development and Scaling of the easyCBM CCSS Middle School Mathematics Measures. Technical Report #1207

Science.gov (United States)

Anderson, Daniel; Irvin, P. Shawn; Patarapichayatham, Chalie; Alonzo, Julie; Tindal, Gerald

2012-01-01

In the following technical report, we describe the development and scaling of the easyCBM CCSS middle school mathematics measures, designed for use within a response to intervention framework. All items were developed in collaboration with experienced middle school mathematics teachers and were written to align with the Common Core State…

Anti-collapse mechanism of CBM fuzzy-ball drilling fluid

Directory of Open Access Journals (Sweden)

Lihui Zheng

2016-03-01

Full Text Available Although fuzzy-ball drilling fluid has been successfully applied in CBM well drilling, it is necessary to study its anti-collapse mechanism so that adjustable coalbed sealing effects, controllable sealing strength, rational sealing cost and controllable reservoir damage degree can be realized. In this paper, laboratory measurement was performed on the uniaxial compressive strength of the plungers of No. 3 coalbed in the Qinshui Basin and the inlet pressure of Ø38 mm coal plunger displacement. The strengths of coal plungers were tested and compared after 2% potassium chloride solution, low-solids polymer drilling fluid and fuzzy-ball drilling fluid were injected into the coal plungers respectively. It is shown that coal strength rises by 38.46% after the fuzzy-ball drilling fluid is injected (in three groups; and that no fuzzy-ball drilling fluid is lost at the displacement pressures of 20.73 and 21.46 MPa, nor 2% potassium chloride solution is leaked at such pressures of 24.79 and 25.64 MPa after the plunger was sealed by the fuzzy-ball drilling fluid. This indicates that the fuzzy-ball drilling fluid can increase the formation resistance to fluid. Indoor microscopic observation was conducted on the sealing process of the fuzzy-ball drilling fluid in sand packs with coal cuttings of three grain sizes (60–80, 80–100 and 100–120 mesh. It is shown that the leakage pathways of different sizes are sealed by the vesicles in the form of accumulation, stretch and blockage. And there are vesicles at the inlet ends of the flowing pathways in the shape of beaded blanket. The impact force of drilling tools on the sidewalls is absorbed by the vesicles due to their elasticity and tenacity, so the sidewall instability caused by drilling tools is relieved. It is concluded that the main anti-collapse mechanisms of the CBM fuzzy-ball drilling fluid are to raise the coal strength, increase the formation resistance to fluid, and buffer the impact of

Borboletas (Lepidoptera: Hesperioidea e Papilionoidea visitantes florais no Jardim Botânico da Universidade Federal de Santa Maria, Santa Maria, RS, Brasil

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Renata Lemes

2008-01-01

Full Text Available http://dx.doi.org/10.5007/2175-7925.2008v21n4p91 Ambientes urbanos como parques e jardins podem oferecer muitos recursos alimentares, além de abrigo e condições favoráveis para a sobrevivência de borboletas. O presente trabalho teve como objetivo fazer um inventário das borboletas visitantes florais e das plantas visitadas por esses insetos no Jardim Botânico da Universidade Federal de Santa Maria (UFSM. No período de março de 2006 a março de 2007, foram feitas 2h de observações semanais das borboletas visitantes fl orais. Em 108h de observação, foram registradas 1114 visitas de 39 espécies de borboletas, associadas a 43 espécies de plantas (21 famílias. Nymphalidae teve a maior riqueza de espécies (S= 18, seguida de Hesperiidae (S= 8, Pieridae (S= 7, Papilionidae (S= 4 e Lycaenidae (S= 2. O pierídeo Phoebis philea philea foi a espécie mais freqüente (187 visitas, seguida dos hesperídeos Urbanus proteus proteus (100, U. teleus (73 e do ninfalídeo Heliconius erato phyllis (71. Lantana camara (Verbenaceae, Eupatorium laevigatum (Asteraceae, Russelia equisetiformis (Scrophulariaceae e Stachytarpheta cayennensis (Verbenaceae foram as plantas mais visitadas. O Jardim Botânico da UFSM é um exemplo de parque urbano que parece possuir recursos florais para alimentação de várias espécies de borboletas, sendo também potencial refúgio para espécies de áreas florestais do entorno.

Design and performance studies of the micro-vertex-detector for the CBM experiment at FAIR

International Nuclear Information System (INIS)

Amar-Youcef, Samir

2012-01-01

The CBM experiment is a fixed target experiment to be installed at the future accelerator facility at GSI/FAIR. It will investigate the properties of nuclear matter at extreme conditions and its underlying strong interaction. The research of the CBM experiment, which focuses on the regime of highest net-baryon densities and moderate temperatures, is complementary to this of the experiments at RHIC/BNL (STAR) and LHC/CERN (ALICE), which mainly focuses on the regime of high energy and zero net-baryon densities. The corresponding conditions in the CBM experiment can be produced in heavy-ion collisions at beam energies between 10 and 40 AGeV. Heavy particles, as e.g. charm carrying particles, could be sensitive to the properties of the medium in the early phase of the collision. However due to the short lifetime of open charm particles, they can only be reconstructed via their decay products and the corresponding track topology. Consequently in order to reconstruct the decay vertex with a high accuracy an ultrathin detector system with excellent spatial resolution is required. For the precise vertexing a microvertex detector (MVD) is envisaged, which has to be located directly behind the target and has to operate in the vacuum. Monolithic Active Pixel Sensors (MAPS) are the most promising candidates for the underlying sensor technology for the MVD of the CBM experiment. In the context of this thesis first attempts haven been initiated in order to integrate mechanically MAPS sensors into an ultra-thin detector dedicated to the CBM experiment. The mechanical integration necessarily needs to contain the MAPS sensors, electrical services and a support structure to cool and mount the sensors. As, apart from the intrinsic properties of the sensor, the support structures contribute notably to the specific functions and properties of the detector, particular care has to be taken during its development. Its implementation is not meant to push already the limits, rather it is

Design and performance studies of the micro-vertex-detector for the CBM experiment at FAIR

Energy Technology Data Exchange (ETDEWEB)

Amar-Youcef, Samir

2012-04-12

The CBM experiment is a fixed target experiment to be installed at the future accelerator facility at GSI/FAIR. It will investigate the properties of nuclear matter at extreme conditions and its underlying strong interaction. The research of the CBM experiment, which focuses on the regime of highest net-baryon densities and moderate temperatures, is complementary to this of the experiments at RHIC/BNL (STAR) and LHC/CERN (ALICE), which mainly focuses on the regime of high energy and zero net-baryon densities. The corresponding conditions in the CBM experiment can be produced in heavy-ion collisions at beam energies between 10 and 40 AGeV. Heavy particles, as e.g. charm carrying particles, could be sensitive to the properties of the medium in the early phase of the collision. However due to the short lifetime of open charm particles, they can only be reconstructed via their decay products and the corresponding track topology. Consequently in order to reconstruct the decay vertex with a high accuracy an ultrathin detector system with excellent spatial resolution is required. For the precise vertexing a microvertex detector (MVD) is envisaged, which has to be located directly behind the target and has to operate in the vacuum. Monolithic Active Pixel Sensors (MAPS) are the most promising candidates for the underlying sensor technology for the MVD of the CBM experiment. In the context of this thesis first attempts haven been initiated in order to integrate mechanically MAPS sensors into an ultra-thin detector dedicated to the CBM experiment. The mechanical integration necessarily needs to contain the MAPS sensors, electrical services and a support structure to cool and mount the sensors. As, apart from the intrinsic properties of the sensor, the support structures contribute notably to the specific functions and properties of the detector, particular care has to be taken during its development. Its implementation is not meant to push already the limits, rather it is

The prototype readout chain for CBM using the AFCK board and its software components

Science.gov (United States)

Loizeau, Pierre-Alain; Emscherman, David; Lehnert, Jörg; Müller, Walter F. J.; Yang, Junfeng

2015-09-01

This paper presents a prototype for the readout chain of the Compressed Baryonic Matter (CBM) experiment using the AFCK FPGA board as Data Processing Board (DPB). The components of the readout chain are described, followed by some test setups, all based on different flavors of AFCK-DPB. Details about the functional blocks in the different versions of the DPB firmware are given, followed by a description of the corresponding software elements.

Quality assurance database for the CBM silicon tracking system

Energy Technology Data Exchange (ETDEWEB)

Lymanets, Anton [Physikalisches Institut, Universitaet Tuebingen (Germany); Collaboration: CBM-Collaboration

2015-07-01

The Silicon Tracking System is a main tracking device of the CBM Experiment at FAIR. Its construction includes production, quality assurance and assembly of large number of components, e.g., 106 carbon fiber support structures, 1300 silicon microstrip sensors, 16.6k readout chips, analog microcables, etc. Detector construction is distributed over several production and assembly sites and calls for a database that would be extensible and allow tracing the components, integrating the test data, monitoring the component statuses and data flow. A possible implementation of the above-mentioned requirements is being developed at GSI (Darmstadt) based on the FAIR DB Virtual Database Library that provides connectivity to common SQL-Database engines (PostgreSQL, Oracle, etc.). Data structure, database architecture as well as status of implementation are discussed.

Native SrTiO3 (001) surface layer from resonant Ti L2,3 reflectance spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Valvidares, Manuel; Huijben, Mark; Yu, Pu; Ramesh, Ramamoorthy; Kortright, Jeffrey

2010-11-03

We quantitatively model resonant Ti L2,3 reflectivity Rs,p(q, hn) from several SrTiO3 (001) single crystals having different initial surface preparations and stored in ambient conditions before and between measurements. All samples exhibit unexpected 300 K Rs(hn) - Rp(hn) anisotropy corresponding to weak linear dichroism and tetragonal distortion of the TiO6 octahedra indicating a surface layer with properties different from cubic SrTiO3. Oscillations in Rs(q) confirm a ubiquitous surface layer 2-3 nm thick that evolves over a range of time scales. Resonant optical constant spectra derived from Rs,p(hn) assuming a uniform sample are refined using a single surface layer to fit measured Rs(q). Differences in surface layer and bulk optical properties indicate that the surface is significantly depleted in Sr and enriched in Ti and O. While consistent with the tendency of SrTiO3 surfaces toward non-stoichiometry, this layer does not conform simply to existing models for the near surface region and apparently forms via room temperature surface reactions with the ambient. This new quantitative spectral modeling approach is generally applicable and has potential to study near-surface properties of a variety of systems with unique chemical and electronic sensitivities.

The carbohydrate-binding module (CBM)-like sequence is crucial for rice CWA1/BC1 function in proper assembly of secondary cell wall materials.

Science.gov (United States)

Sato, Kanna; Ito, Sachiko; Fujii, Takeo; Suzuki, Ryu; Takenouchi, Sachi; Nakaba, Satoshi; Funada, Ryo; Sano, Yuzou; Kajita, Shinya; Kitano, Hidemi; Katayama, Yoshihiro

2010-11-01

We recently reported that the cwa1 mutation disturbed the deposition and assembly of secondary cell wall materials in the cortical fiber of rice internodes. Genetic analysis revealed that cwa1 is allelic to bc1, which encodes glycosylphosphatidylinositol (GPI)-anchored COBRA-like protein with the highest homology to Arabidopsis COBRA-like 4 (COBL4) and maize Brittle Stalk 2 (Bk2). Our results suggested that CWA1/BC1 plays a role in assembling secondary cell wall materials at appropriate sites, enabling synthesis of highly ordered secondary cell wall structure with solid and flexible internodes in rice. The N-terminal amino acid sequence of CWA1/BC1, as well as its orthologs (COBL4, Bk2) and other BC1-like proteins in rice, shows weak similarity to a family II carbohydrate-binding module (CBM2) of several bacterial cellulases. To investigate the importance of the CBM-like sequence of CWA1/BC1 in the assembly of secondary cell wall materials, Trp residues in the CBM-like sequence, which is important for carbohydrate binding, were substituted for Val residues and introduced into the cwa1 mutant. CWA1/BC1 with the mutated sequence did not complement the abnormal secondary cell walls seen in the cwa1 mutant, indicating that the CBM-like sequence is essential for the proper function of CWA1/BC1, including assembly of secondary cell wall materials.

C-reactive protein gene polymorphisms and myocardial infarction risk: a meta-analysis and meta-regression.

Science.gov (United States)

Zhu, Yanbin; Liu, Tongku; He, Haitao; Sun, Yuqing; Zhuo, Fengling

2013-12-01

C-reactive protein (CRP), the classic acute-phase protein, plays an important role in the etiology of myocardial infarction (MI). Emerging evidence has shown that the common polymorphisms in the CRP gene may influence an individual's susceptibility to MI; but individually published studies showed inconclusive results. This meta-analysis aimed to derive a more precise estimation of the associations between CRP gene polymorphisms and MI risk. A literature search of PubMed, Embase, Web of Science, and China BioMedicine (CBM) databases was conducted on articles published before June 1st, 2013. Crude odds ratio (OR) with 95% confidence interval (CI) were calculated. Nine case-control studies were included with a total of 2992 MI patients and 4711 healthy controls. The meta-analysis results indicated that CRP rs3093059 (T>C) polymorphism was associated with decreased risk of MI, especially among Asian populations. However, similar associations were not observed in CRP rs1800947 (G>C) and rs2794521 (G>A) polymorphisms (all p>0.05) among both Asian and Caucasian populations. Univariate and multivariate meta-regression analyses showed that ethnicity may be a major source of heterogeneity. No publication bias was detected in this meta-analysis. In conclusion, the current meta-analysis indicates that CRP rs3093059 (T>C) polymorphism may be associated with decreased risk of MI, especially among Asian populations.

OCORRÊNCIA E DURAÇÃO DAS TEMPERATURAS MÍNIMAS DIÁRIAS DO AR PREJUDICIAIS À FECUNDAÇÃO DAS FLORES DO ARROZ EM SANTA MARIA. RS. III: PROBABILIDADES DE OCORRÊNCIA DA DURAÇÃO DAS TEMPERATURAS BAIXAS

Directory of Open Access Journals (Sweden)

Flávio Miguel Schneider

1992-04-01

Full Text Available Utilizando os valores das temperaturas mínimas, máximas e das 21 h, hora local, dos meses de dezembro, janeiro, fevereiro e março registradas na Estação Climatológica Principal de Santa Maria, RS, determinaram-se as probabilidades de ocorrência da duração máxima de horas com temperatura do ar ≤ 10, 11, 12, 13, 14, 15, 16 e 17,0°C e de seqüências de dias consecutivos com no mínimo uma hora de duração com temperatura do ar ≤ 15, 16 e 17,0°C. Essas probabilidades foram obtidas para cada decêndio dos meses estudados. Os resultados evidenciam que o risco de ocorrência de temperaturas prejudiciais à fecundação das flores da cultura do arroz é bem menor no 2° e 3° decêndio do mês de fevereiro. Deve-se, portanto, semear e/ou escolher ciclo de cultivar de arroz que possibilite que a fase de floração ocorra durante o 2° e 3° decêndio do mês de fevereiro.

Fusion power core engineering for the ARIES-ST power plant

International Nuclear Information System (INIS)

Tillack, M.S.; Wang, X.R.; Pulsifer, J.; Malang, S.; Sze, D.K.; Billone, M.; Sviatoslavsky, I.

2003-01-01

ARIES-ST is a 1000 MWe fusion power plant based on a low aspect ratio 'spherical torus' (ST) plasma. The ARIES-ST power core was designed to accommodate the unique features of an ST power plant, to meet the top-level requirements of an attractive fusion energy source, and to minimize extrapolation from the fusion technology database under development throughout the world. The result is an advanced helium-cooled ferritic steel blanket with flowing PbLi breeder and tungsten plasma-interactive components. Design improvements, such as the use of SiC inserts in the blanket to extend the outlet coolant temperature range were explored and the results are reported here. In the final design point, the power and particle loads found in ARIES-ST are relatively similar to other advanced tokamak power plants (e.g. ARIES-RS [Fusion Eng. Des. 38 (1997) 3; Fusion Eng. Des. 38 (1997) 87]) such that exotic technologies were not required in order to satisfy all of the design criteria. Najmabadi and the ARIES Team [Fusion Eng. Des. (this issue)] provide an overview of ARIES-ST design. In this article, the details of the power core design are presented together with analysis of the thermal-hydraulic, thermomechanical and materials behavior of in-vessel components. Detailed engineering analysis of ARIES-ST TF and PF systems, nuclear analysis, and safety are given in the companion papers

The Silicon Tracking System of the CBM Experiment at FAIR

Science.gov (United States)

Heuser, Johann M.

The Compressed Baryonic Matter (CBM) experiment at FAIR will conduct a systematic research program to explore the phase diagram of strongly interacting matter at highest net baryon densities and moderate temperatures. These conditions are to be created in collisions of heavy-ion beams with nuclear targets in the projectile beam energy range of 2 to 45 GeV/nucleon, initially coming from the SIS 100 synchrotron (up to 14 GeV/nucleon) and in a next step from SIS 300 enabling studies at the highest net baryon densities. Collision rates up to 107 per second are required to produce very rare probes with unprecedented statistics in this energy range. Their signatures are complex. These conditions call for detector systems designed to meet the extreme requirements in terms of rate capability, momentum and spatial resolution, and a novel data acquisition and trigger concept which is not limited by latency but by throughput. In the paper we describe the concept and development status of CBM's central detector, the Silicon Tracking System (STS). The detector realizes a large, highly granular and redundant detector system with fast read-out, and lays specific emphasis on low material budget in its physics aperture to achieve for charged particle tracks a momentum resolution of δp/p ≈ 1% at p > 1 GeV/c, at >95% track reconstruction efficiency. The detector employs 1220 highly segmented double-sided silicon micro-strip sensors of 300 µm thickness, mounted into 896 modular structures of various types that are aggregated on 106 low-mass carbon fiber ladders of different sizes that build up the tracking stations. The read-out electronics with its supply and cooling infrastructure is arranged at the periphery of the ladders, and provides a total channel count of 1.8 million. The signal transmission from the silicon sensors to the electronics is realized through ultra-thin multi-line aluminum-polyimide cables of up to half a meter length. The electronics generates a free

The silicon tracking system of the CBM experiment at FAIR

International Nuclear Information System (INIS)

Heuser, Johann M.

2015-01-01

The Compressed Baryonic Matter (CBM) experiment at FAIR will conduct a systematic research program to explore the phase diagram of strongly interacting matter at highest net baryon densities and moderate temperatures. These conditions are to be created in collisions of heavy-ion beams with nuclear targets in the projectile beam energy range of 2 to 45 GeV/nucleon, initially coming from the SIS 100 synchrotron (up to 14 GeV/nucleon) and in a next step from SIS 300 enabling studies at the highest net baryon densities. Collision rates up to 10"7 per second are required to produce very rare probes with unprecedented statistics in this energy range. Their signatures are complex. These conditions call for detector systems designed to meet the extreme requirements in terms of rate capability, momentum and spatial resolution, and a novel data acquisition and trigger concept which is not limited by latency but by throughput. In the paper we describe the concept and development status of CBM's central detector, the Silicon Tracking System (STS). The detector realizes a large, highly granular and redundant detector system with fast read-out, and lays specific emphasis on low material budget in its physics aperture to achieve for charged particle tracks a momentum resolution of δp/p≈1% at p > 1 GeV/c, at >95% track reconstruction efficiency. The detector employs 1220 highly segmented double-sided silicon micro-strip sensors of 300 μm thickness, mounted into 896 modular structures of various types that are aggregated on 106 low-mass carbon fiber ladders of different sizes that build up the tracking stations. The read-out electronics with its supply and cooling infrastructure is arranged at the periphery of the ladders, and provides a total channel count of 1.8 million. The signal transmission from the silicon sensors to the electronics is realized through ultra-thin multi-line aluminum-polyimide cables of up to half a meter length. The electronics generates a free

FITOSSOCIOLOGIA DE FRAGMENTOS DE FLORESTA ESTACIONAL DECIDUAL NO ESTADO DE SANTA CATARINA – BRASIL

Directory of Open Access Journals (Sweden)

Lauri Amândio Schorn

2014-01-01

Full Text Available This study aimed to evaluate the species composition and structure of Seasonal Deciduous Forest in the southern Brazilian state of Santa Catarina, including the tree/shrub component and the natural regeneration. We also compared the floristic composition between the components and discussed about the conservation condition of forests. The study was based on sample plots established by the Floristic and Forest Inventory of Santa Catarina state. Tree/shrub component was sampled by 78 plots placed systematically with 4,000 m² of sample area each, were individuals with DBH (diameter at breast height ≥ 10 cm was measured. Regeneration (DBH 1.50 m was sampled in subplots of 100 m² each. Structure and diversity of sample plots were analyzed in both components; species were classified by their ecologic group. To test the association between components was made a Non-metric Multidimensional Scaling (NMSD and Mantel test. We sampled 245 species, among them 215 in the tree/shrub component (79 of them exclusive, 165 species in the natural regeneration (30 exclusive ones and 136 species common to the two components. The association between components was confirmed with NMSD and Mantel test (r = 0.34; p = 0.001. Species with major importance value were mostly early secondary species that emphasizes the consequences of long term exploitation and degradation of Seasonal Deciduous Forest in Santa Catarina.

O contato linguístico na Serra dos Tapes, RS: implicações para o ensino do Português brasileiro com manutenção do pomerano

OpenAIRE

Amaral, Luís Isaías Centeno do; Universidade Federal de Pelotas - Centro de Letras e Comunicaçao; Mackedanz, Daiane; Universidade Federal de Pelotas - Centro de Letras e Comunicação

2016-01-01

RESUMO: o artigo é resultado de estudo com uma turma de pré-escolar, na Escola Municipal de Ensino Fundamental Martinho Lutero, localizada em Santa Augusta, RS. Objetivamos lançar reflexões acerca do contato linguístico pomerano e português brasileiro; mais precisamente, como a adoção de uma pedagogia culturalmente sensível às especificidades sociolinguísticas dos alunos influencia o processo de ensino do português, haja vista que mais da metade da turma analisada ingressou na escola ou como ...

COX-2 rs689466, rs5275, and rs20417 polymorphisms and risk of head and neck squamous cell carcinoma: a meta-analysis of adjusted and unadjusted data

International Nuclear Information System (INIS)

Leng, Wei-Dong; Wen, Xiu-Jie; Kwong, Joey S. W.; Huang, Wei; Chen, Jian-Gang; Zeng, Xian-Tao

2016-01-01

Numerous case–control studies have been performed to investigate the association between three cyclooxygenase-2 (COX-2) polymorphisms (rs20417 (−765G > C), rs689466 (−1195G > A), and rs5275 (8473 T > C)) and the risk of head and neck squamous cell carcinoma (HNSCC). However, the results were inconsistent. Therefore, we conducted this meta-analysis to investigate the association. We searched in PubMed, Embase, and Web of Science up to January 20, 2015 (last updated on May 12, 2016). Two independent reviewers extracted the data. Odds ratios (ORs) with their 95 % confidence intervals (CIs) were used to assess the association. All statistical analyses were performed using the Review Manager (RevMan) 5.2 software. Finally 8 case–control studies were included in this meta-analysis. For unadjusted data, an association with increased risk was observed in three genetic models in COX-2 rs689466 polymorphism; however, COX-2 rs5275 and rs20417 polymorphisms were not related to HNSCC risk in this study. The pooled results from adjusted data all revealed non-significant association between these three polymorphisms and risk of HNSCC. We also found a similar result in the subgroup analyses, based on both unadjusted data and adjusted data. Current results suggest that COX-2 rs689466, rs5275, and rs20417 polymorphisms are not associated with HNSCC. Further large and well-designed studies are necessary to validate this association

Características físico-químicas de extratos de erva-mate (Ilex paraguariensis St. Hil no estado de Santa Catarina.

Directory of Open Access Journals (Sweden)

Dorli Mário Da Croce

2010-08-01

Full Text Available O objetivo deste trabalho é avaliar as características físico-químicas de extratos de erva-mate (Ilex paraguariensis St. Hil, como a umidade e substâncias voláteis a 105°C % (p/p, resíduo mineral fixo, % (p/p resíduo mineral fixo insolúvel em solução de HCL a 10%, v/v, % (p/p, extrato aquoso, % (p/p e cafeína, % (p/p. Os resultados obtidos nas análises amostradas foram comparados com as normas estabelecidas pela portaria 234 de 25 de março de 1998, da Agência Nacional de Vigilância Sanitária (ANVS, Ministério da Saúde. As amostras foram coletadas em quatro grandes regiões de ocorrência de erva-mate no estado de Santa Catarina, apresentando condições específicas de solo e clima. Os resultados obtidos indicam que, na época de maior crescimento vegetativo, compreendido entre os meses de setembro a dezembro, poucas amostras atingiram os índices de cafeína estabelecidos na portaria. Nas avaliações feitas em janeiro, fevereiro, março, junho e julho, a maioria das amostras atingiram o índice mínimo de cafeína estabelecido em 0,5g/100g de erva-mate. As demais características analisadas então de acordo com os índices estabelecidos na legislação.

The universal read-out controller for CBM at FAIR

Energy Technology Data Exchange (ETDEWEB)

Manz, Sebastian; Abel, Norbert; Gebelein, Jano [Kirchhoff-Institut fuer Physik, Heidelberg (Germany); Collaboration: CBM-Collaboration

2011-07-01

Since 2007 we design and develop the firmware for the read-out controller (ROC) for data acquisition of the CBM detector at FAIR. While our first implementation solely focused on the nXYTER chip, today we are also designing and implementing readout logic for the GET4 chip which is supposed to be part of the time of flight (TOF) detector. Furthermore, we fully support both Ethernet and Optical transport as two transparent solutions. This addresses the different requirements of a laboratory setup and the final detector setup respectively. The usage of a strict modularization of the Read Out Controller firmware enables us to provide an Universal ROC where front-end specific logic and transport logic can be combined in a very flexible way. Fault tolerance techniques are only required for some of those modules and hence are only implemented there.

Simulation and reconstruction of free-streaming data in CBM

International Nuclear Information System (INIS)

Friese, Volker

2011-01-01

The CBM experiment will investigate heavy-ion reactions at the FAIR facility at unprecedented interaction rates. This implies a novel read-out and data acquisition concept with self-triggered front-end electronics and free-streaming data. Event association must be performed in software on-line, and may require four-dimensional reconstruction routines. In order to study the problem of event association and to develop proper algorithms, simulations must be performed which go beyond the normal event-by-event processing as available from most experimental simulation frameworks. In this article, we discuss the challenges and concepts for the reconstruction of such free-streaming data and present first steps for a time-based simulation which is necessary for the development and validation of the reconstruction algorithms, and which requires modifications to the current software framework FAIRROOT as well as to the data model.

Myxomycetes de Florianópolis (Santa Catarina - Brasil Myxomycetes of Florianópolis (State of Santa Catarina - Brazil

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Laise de Holanda Cavalcanti

1994-07-01

Full Text Available Considerando a inexistência de registros de ocorrência de Myxomycetes em Florianópolis, realizou- se coletas nas matas da Lagoa do Peri e Lagoa da Conceição, em 1990, assinalando-se as seguintes espécies : Lycogala exiguum Morg. (Enteridiaceae ; Cribraria languescem Rex, C. vulgaris Sclir. (Cribrariaceae ; Arcyria cinerea ( Bull. Pers. , Hemitrichia serpula ( Scop. Rost., H. calyculata ( Speg. Farr e Hemitrichia sp (Trichiaceae ; Stemonitis fusca Roth. e S. smithii Macbr. (Stemonitaceae. Exsicatas encontram-se depositadas no herbário UFP. Lycogala exiguum é assinalada pela primeira vez para Santa Catarina, Cribraria languescens para a região Sul e Cribraria vulgaris para o Brasil. O levantamento eleva para 47 o número de espécies referidas para o Estado de Santa Catarina. Fornece-se um histórico do estudo deste qrupo de organismos em Santa Catarina bem como a área de ocorrência de cada espécie no Estado e nas diferentes regiões do Brasil.A survey on Myxomycetes was made in the woods of Lagoa do Peri and Lagoa da Conceição in 1990, considering the absence of reports of this kind for the city of Florianópolis, when the following species were registered: Lycogala exiguum Morg. (Enteridiaceae; Cribraria languescem Rex, C. vulgaris Schr. (Cribrariaceae; Arcyria cinerea (Bull. Pers. Hemitrichia serpula (Scop. Rost., H. calyculata (Speg. Fair and Hemitrichia sp (Trichiaceae; Stemonitis fusca Roth, and S. smithii Macbr. (Stemonitaceae. Exicates are deposited at the herbarium UFP. Lycogala exiguum is noted for the first time in the state of Santa Catarina, Cribraria languescem in the South and Cribraria vulgaris in Brazil. The survey raises up the number of registers refered to the state of Santa Catarina to 47 species. A review of the studies on this group of organisms in Santa Catarina is given as well as the area where each species occur in this state and in different regions of Brazil.

Correlation of Fetuin-A gene rs1071592 and rs2593813 single nucleotide polymorphisms with polycystic ovary syndrome

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Juan YI

2016-10-01

Full Text Available Objective 　To investigate the relations of Fetuin-A gene rs1071592 and rs2593813 single nucleotide polymorphisms (SNPs with the affect ability to polycystic ovary syndrome (PCOS and its endocrine and metabolic characteristics in Chongqing Han population. Methods 　A case-control study was performed in Chinese Han subjects. The clinical data of 156 cases of normal control and 147 cases of PCOS patients were collected, and their blood glucose, lipids, sex hormone and other biochemical indexes were determined, the SNPs of rs1071592 and rs2593813 were genotyped by TaqMan SNP Genotyping Assay. Hyperinsulinemic-euglycemic clamp was performed in 147 PCOS women and 20 controls. The relative risk of developing PCOS in women with rs1071592 genotype was assessed using a binary logistic regression analysis. Results 　The distribution frequency of Fetuin-A gene homozygous rs1071592 AA genotype and A allele was significantly increased in PCOS patients than in controls (Pc0.05. Binary logistic regression analysis showed that the risk of developing PCOS was 4.93 times high in women with AA genotype of rs1071592 (OR=4.933, 95%CI 1.593-15.278, P0.05. Conclusion 　People with SNPs variants of rs1071592 in Fetuin-A gene may have an increased genetic susceptibility to PCOS. However, there won't be significant relationship between SNP of rs2593813 at Fetuin-A gene and PCOS. DOI: 10.11855/j.issn.0577-7402.2016.09.07

O Flúor nas águas subterrâneas da Formação Santa Maria, na região de Santa Cruz do Sul e Venâncio Aires, RS, Brasil

OpenAIRE

Maria Paula Casagrande Marimon

2006-01-01

Concentrações de fluoreto, até 11 mg L-1, têm sido detectadas no aqüífero da Formação Santa Maria, Sistema Aqüífero Guarani, na região central do Estado do Rio Grande do Sul, Brasil. As águas subterrâneas são utilizadas para abastecimento público e levaram a incidência de fluorose dental. Esta área é a maior produtora de tabaco no Brasil, com uma longa história de aplicação de fertilizantes. Duas hipóteses são investigadas na busca de elucidar a origem das anomalias de flúor, a primeira, se r...

RS CV sub n binary systems

International Nuclear Information System (INIS)

Linsky, J.L.

1984-01-01

An attempt is made to place in context the vast amount of data obtained as a result of X-ray, ultraviolet, optical, and microwave observations of RS CVn and similar spectroscopic binary systems. Emphasis is on the RS CVn systems and their long period analogs. The following questions are considered: (1) are the original defining characteristics still valid and still adequate; (2) what is the evidence for discrete active regions; (3) have any meaningful physical properties for the atmospheres of RS CVn systems been derived; (4) what do the flare observations tell about magnetic fields in RS CVn systems; (5) is there evidence for systematic trends in RS CVn systems with spectral type

Challenges for secondary vertex reconstruction in CBM at SIS100 and SIS300 at FAIR

International Nuclear Information System (INIS)

Lymanets, A.; Kotynia, A.; Heuser, J.

2010-01-01

Full text: The CBM experiment at FAIR will explore the QCD phase diagram in the region of highest baryon densities. In contrast to other experimental programs in the same energy domain, CBM will be able to explore rare probes such as charm and dileptons due to its capability of running at interaction rates as high as 10 MHz. In order to cope with the related experimental challenges detailed simulations studies as well as extensive R and D activities on the detector and readout systems are ongoing. In this contribution, the challenges of open charm measurement in pA collisions, e.g. already at SIS100, and in AA collisions at SIS300 will be investigated. In order to extract open charm decays from the large background of produced charged particles, secondary vertex reconstruction with a precision of less than 0.1 mm is required. The involved tracking and reconstruction procedures have to be fast in order to allow their implementation already on the trigger level. Prerequisite for this are ultra-low mass, fast and radiation tolerant silicon detectors. These two aspects of a finally successful measurement, hardware development and reconstruction routines, are being developed in close contact to each other and their status is demonstrated in this talk. (author)

Perfil antropométrico e a relação da flexibilidade com a dor e desconforto em trabalhadores da indústria de Santa Cruz do Sul – RS

Directory of Open Access Journals (Sweden)

Patrik Nepomuceno

2016-10-01

Full Text Available Trabalhadores industriários estão expostos a diversas situações que podem agravar a sua saúde. A promoção da saúde no trabalho é de extrema importância e exige intervenção interdisciplinar. Objetivo: identificar o perfil antropométrico e a relação de flexibilidade com a presença de dor e desconforto em trabalhadores da indústria do município de Santa Cruz do Sul, RS. Método: Trata-se de um estudo transversal com trabalhadores industriários. Na avaliação antropométrica foram analisados índice de massa corporal e percentual de gordura, já para a flexibilidade foram realizados os testes do manguito rotador e sentar e alcançar. A dor e desconforto foi identificada através de uma figura do corpo humano onde eles referiam estes sintomas. Resultados: a maioria dos industriários apresentam excesso de peso (56,4% e bom percentual de gordura (49,2%, porém possuem resultados inadequados de flexibilidade de ombro (71,0% e parte posterior de tronco e pernas (64,6% e presença de dor e desconforto em ombros (50% e costas (26,6%. Ao relacionar a flexibilidade com a presença de dor e desconforto, percebe-se que as variáveis não se relacionam diretamente. Considerações finais: o perfil dos trabalhadores da indústria se caracteriza por excesso de peso, baixa aptidão na flexibilidade e presença de dor e desconforto. Sobre a dor e desconforto observa-se uma tendência de associação entre níveis de flexibilidade inadequada e a presença destes sintomas.

Technical Adequacy of the easyCBM[R] Mathematics Measures: Grades 3-8, 2009-2010 Version. Technical Report #1007

Science.gov (United States)

Nese, Joseph F. T.; Lai, Cheng-Fei; Anderson, Daniel; Jamgochian, Elisa M.; Kamata, Akihito; Saez, Leilani; Park, Bitnara J.; Alonzo, Julie; Tindal, Gerald

2010-01-01

In this technical report, data are presented on the practical utility, reliability, and validity of the easyCBM[R] mathematics (2009-2010 version) measures for students in grades 3-8 within four districts in two states. Analyses include: minimum acceptable within-year growth; minimum acceptable year-end benchmark performance; internal and…

Revisão e análise cladística de Serdia Stål (Heteroptera, Pentatomidae, Pentatomini Review and cladistic analysis of Serdia Stål (Heteroptera, Pentatomidae, Pentatomini

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Nora Denise Fortes de Fortes

2005-09-01

Full Text Available Treze espécies são hoje incluídas no gênero: S. apicicornis, Stål, 1860; S. beckerae Thomas & Rolston, 1985; S. calligera Stål, 1860; S. concolor Ruckes, 1958; S. costalis Ruckes, 1958; S. delphis Thomas & Rolston, 1985; S. inspersipes Stål, 1860; S. lobata Thomas & Rolston, 1985; S. rotundicornis Becker, 1967 e S. ruckesi Thomas & Rolston, 1985. Cinco novas espécies são descritas: S. indistincta sp. nov (Irai, Rio Grande do Sul, S. bicolor sp. nov (Ponta Grossa, Paraná, S. maculata sp. nov (Itatiaia, Rio de Janeiro, S. máxima sp. nov (Imbituba, Santa Catarina e S. robusta sp. nov (Itatiaia, Rio de Janeiro do Brasil. A análise cladística foi realizada usando 40 caracteres e 21 táxons. O gênero Tibilis Stål, 1860; Neotibilis Grazia & Barcellos, 1994 e Similliserdia Fortes & Grazia, 1998 foram usados como grupo-externo. A monofilia de Serdia foi sustentada por 3 sinapomorfias: ápice do escutelo com margens enegrecidas, machos com a parede da taça genital espessada com processos em aba, fêmeas com o espessamento da íntima vaginal situado na metade posterior das gonapófises 9 e projetando-se ventralmente. O subgênero Brasiliicola Kirkaldy, 1909 é considerado sinônimo junior de Serdia. São fornecidas ilustrações, mapas de distribuição geográfica e chave para as espécies.Thirteen species are presently included in the genus: S. apicicornis Stål, 1860; S. beckerae Thomas & Rolston, 1985; S. bihamulata, Thomas & Rolston, 1985; S. calligera Stål, 1860; S. concolor Ruckes, 1958; S. costalis Ruckes, 1958; S. delphis Thomas & Rolston, 1985; S. inspersipes Stål, 1860; S. limbatipennis Stål, 1860; S. lobata Thomas & Rolston, 1985; S. quadridens Thomas & Rolston, 1985; S. rotundicornis Becker, 1967, and S. ruckesi Thomas & Rolston, 1985. Five new species are described: S.indistincta sp. nov. (Iraí; Rio Grande do Sul, S. bicolor sp. nov. (Ponta Grossa; Paraná S. maculata sp. nov. (Itatiaia; Rio de Janeiro S. maxima sp. nov

Avaliação da compatibilidade entre processos produtivos e os ecossistemas locais pela determinação da capacidade suporte dos recursos hídricos: um estudo de caso em Santa Cruz do Sul, RS

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Adilson Ben da Costa

2010-11-01

Full Text Available A presente pesquisa descreve a aplicação de métodos ecotoxicológicos para avaliar a capacidade de suporte do rio Pardinho, município de Santa Cruz do Sul, RS, frente ao lançamento de efluentes de diferentes origens: estação de tratamento de esgoto doméstico, frigorífico de suínos, indústria de alimentos (massas e biscoitos, indústria de curtimento de couro, indústria têxtil e lavanderia hospitalar. Os resultados obtidos permitiram identificar que em uma situação na qual qualquer um destes efluentes fosse lançado neste corpo receptor, mesmo que de forma isolada, resultaria em sérios prejuízos ambientais decorrentes de efeitos agudos e crônicos. A baixa vazão deste recurso hídrico reduz por conseqüência a sua capacidade de suportar impactos deste tipo, denunciando uma completa incompatibilidade entre as atividades geradoras destes resíduos e o ecossistema local. Assim, a alternativa para compatibilizar estes fatores passa pela otimização de processos industriais e a implantação de políticas voltadas ao reuso de águas no processo, de forma a minimizar o volume de efluente gerado e a sua ecotoxicidade.

40 CFR 180.1114 - Pseudomonas fluorescens A506, Pseudomonas fluorescens 1629RS, and Pseudomonas syringae 742RS...

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Pseudomonas fluorescens A506, Pseudomonas fluorescens 1629RS, and Pseudomonas syringae 742RS; exemptions from the requirement of a tolerance... Tolerances § 180.1114 Pseudomonas fluorescens A506, Pseudomonas fluorescens 1629RS, and Pseudomonas syringae...

Santa Fe Alliance for Science: The First Eight Years

Science.gov (United States)

Eisenstein, Robert A.

2013-04-01

The Santa Fe Alliance for Science (SFAFS) was founded in May, 2005. SFAFS exists to provide assistance in K-14 math and science education in the greater Santa Fe area. It does this via extensive programs (1) in math and science tutoring at Santa Fe High School, Santa Fe Community College and to a lesser degree at other schools, (2) science fair advising and judging, (3) its ``Santa Fe Science Cafe for Young Thinkers'' series, (4) a program of professional enrichment for K-12 math and science teachers, and (5) a fledging math intervention program in middle school math. Well over 150 STEM professionals, working mostly as volunteers, have contributed since our beginning. Participation by students, parents and teachers has increased dramatically over the years, leading to much more positive views of math and science, especially among elementary school students and teachers. Support from the community and from local school districts has been very strong. I will present a brief status report on SFAFS activities, discuss some of the lessons learned along the way and describe briefly some ideas for the future. More information can be found at the SFAFS website, www.sfafs.org.

Eficácia de Atrativos Alimentares na Captura de Zaprionus indianus (Gupta em Pomar de Figo em Santa Maria – RS

Directory of Open Access Journals (Sweden)

Mauricio Batistella Pasini

2011-07-01

Abstract. Aiming to evaluate the efficiency of food baits for monitoring and alternative control of fig fly [Zaprionus indianus (Gupta], held this job. The study was conducted in Sector Fruit of the Polytechnic College, University of Santa Maria, from January 22 to April 22, 2009 in fig orchard (Ficus carica L.. As model of trap we used Pet. bottles of 1 L. Guava juice, jelly palm juice and fig juice with different solvents were use as food baits, with 200 ml solution per bottle. The values were subjected to statistical analysis. The solutions fig juice + rum (50% +50% and fig juice + water (50% +50% showed higher levels of adult capture of Z. indianus, suggesting its use in fly monitoring. The alcohol-based solutions are inefficient.

Technology of double casing tubes & a binary cycle system for hole cleaning for CBM multi-branch horizontal wells

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Yong Yang

2017-03-01

Full Text Available At present, the aeration-assisted cutting-carrying technology is faced with complexities in the drilling of CBM multi-branch horizontal wells. For example, the aerating pressure is hardly maintained, and the borehole instability may happen. In view of these prominent problems, the technology of double casing tubes & a binary cycle system suitable for CBM multi-branch horizontal wells was developed according to the Venturi principle by means of parasitic tube insufflation which is used for well control simulation system. Then, a multiphase flow finite element model was established for the fluid-cutting particle system in this drilling condition. This technology was tested in field. Double-casing tubes cementing is adopted in this technology and a jet generator is installed at the bottom of the inner casing. In the process of drilling, the drilling fluid injected through double intermediate casing annulus is converted by the jet generator into a high-efficiency steering water jet, which, together with the water jet generated by the bit nozzle, increases the fluid returning rate in the inner annulus space. It is indicated from simulation results that the cutting-carrying effect is the best when the included angle between the nozzle of the jet generator and the vertical direction is 30°. Besides, the influential laws of cutting size, primary cycle volume, accessory cycle volume and drilling velocity on hole cleaning are figured out. It is concluded that this technology increases the flow rate of drilling fluid in annulus space, the returning rate of drilling fluid significantly and the cutting-carrying capacity. It is currently one of the effective hole cleaning technologies for CBM multi-branch horizontal wells where fresh water is taken as the drilling fluid.

33 CFR 334.730 - Waters of Santa Rosa Sound and Gulf of Mexico adjacent to Santa Rosa Island, Air Force Proving...

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Waters of Santa Rosa Sound and..., Fla. 334.730 Section 334.730 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.730 Waters of Santa Rosa...

Fauna do solo em áreas com Eucalyptus spp. e Pinus elliottii, Santa Maria, RS.

Directory of Open Access Journals (Sweden)

Maria Izabel Jacques Soares

2009-10-01

Full Text Available Normal 0 21 MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabela normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman";} Este trabalho, com início na primavera de 1996 e término no inverno de 1997, teve como objetivo realizar o levantamento populacional da fauna do solo em áreas com Eucalyptus spp. e Pinus elliottii, situadas no Campus da Universidade Federal de Santa Maria, Rio Grande do Sul, Brasil. Para a coleta do solo, utilizou-se um extrator, formando-se amostras em dez pontos, nas profundidades de 0-5, 5-10, 10-15 e de 15-20 cm, em cada estação do ano. Por meio deste estudo, pôde-se identificar alguns representantes dos Phylum Annelida e Arthropoda que participam do contexto fauna-solo-vegetação. O total de indivíduos, seu respectivo percentual e número de indivíduos por metro quadrado foram obtidos. Observou-se o predomínio do Phylum Arthropoda e, mais especificamente, da classe Insecta na área com Eucalyptus spp. e do Phylum Annelida na área com Pinus elliottii. A variável profundidade originou modelos matemáticos que explicam a distribuição populacional dentre as áreas estudadas. A variável estação do ano não apresentou uma diferença significativa. Não foi possível, portanto, estabelecer um modelo de distribuição populacional.

Optical quality assurance procedures for the sensors of CBM STS detector

Energy Technology Data Exchange (ETDEWEB)

Lavrik, Evgeny [Physikalisches Institut der Universitaet Tuebingen (Germany); Collaboration: CBM-Collaboration

2016-07-01

The Compressed Baryonic Matter (CBM) experiment at FAIR aims to study the properties of nuclear matter at high net-baryon densities. The Silicon Tracking System (STS) is the key detector to reconstruct charged particle tracks created in heavy-ion interactions. In order to assure the quality of about 1300 silicon sensors, highly efficient and highly automated procedures need to be developed. In this contribution we report on a microscope camera based optical inspection system, used to scan along the individual sensors to recognize and classify sensor defects. Examples of these defects are: photo-resist residues, top metallization layer lithography defects, surface scratches. In order to separate and classify these defects various image-processing algorithms are used, including: pattern recognition, object classification etc.

Local smoke-free policy development in Santa Fe, Argentina.

Science.gov (United States)

Sebrié, Ernesto M; Glantz, Stanton A

2010-04-01

To describe the process of approval and implementation of a comprehensive smoke-free law in the province of Santa Fe, Argentina, between 2005 and 2009. Review of the Santa Fe smoke-free legislation, articles published in local newspapers and documentation on two lawsuits filed against the law, and interviews with key individuals in Santa Fe. Efforts to implement smoke-free policies in Santa Fe began during the 1990s without success, and resumed in 2005 when the provincial Legislature approved the first 100% smoke-free subnational law in Argentina. There was no strong opposition during the discussions within the legislature. As in other parts of the world, pro-tobacco industry interests attempted to block the implementation of the law using well known strategies. These efforts included a controversy media campaign set up, the creation of a hospitality industry association and a virtual smokers' rights group, the introduction of a counterproposal seeking modification of the law, the challenge of the law in the Supreme Court, and the proposal of a weak national bill that would 'conflict' with the subnational law. Tobacco control advocates sought media attention as a strategy to protect the law. Santa Fe is the first subnational jurisdiction in Latin America to have enacted a comprehensive smoke-free policy following the recommendations of the World Health Organization (WHO) Framework Convention on Tobacco Control. After 3 years of implementation, pro-tobacco industry forces failed to undermine the law. Other subnational jurisdictions in Argentina, as well as in Mexico and Brazil are following the Santa Fe example.

The Causes and Prevention Measures of Stuck Pump Phenomenon of Rod-pumped Well in CBM Field

Science.gov (United States)

Yonggui, Mei

2018-02-01

In the process of CBM field exploitation, in order to realize the drainage equipment to work continuous stably, the article pays attention to study and solve the stuck pump problem, and aim of reducing reservoir damage and lowing production costs. Through coal particles stuck pump experiment and sediment composition analysis, we find out five primary cause of stuck pump phenomenon: sand from coal seam, sediment from ground, iron corrosion, iron scrap caused by eccentric wear, coal cake. According to stuck pump mechanism, the article puts forward 8 measures to prevent stuck pump phenomenon, and the measures are focused on technology optimization, operation management and drainage process control. After 7 years production practice, the yearly stuck pump rate has dropped from 8.9% to 1.2%, and the pump inspection period has prolonged 2 times. The experiment result shows that pure coal particles cannot cause stuck pump, but sand, scrap iron, and iron corrosion are the primary cause of stuck pump. The article study and design the new pipe string structure that the bottom of the pipe string is open. This kind of pipe string applied the sedimentation terminal velocity theory to solve the stuck pump phenomenon, and it can be widely used in CBM drainage development.

PARQUES DE PRODUÇÃO DE ENERGIA EÓLICA E TRANSFORMAÇÕES NA PAISAGEM – ESTUDO DE CASO EM SANTA VITÓRIA DO PALMAR/RS

Directory of Open Access Journals (Sweden)

Anelize Milano Cardoso

2015-07-01

Full Text Available Numa região das mais isoladas do Estado, no extremo sul do país, logo no início da BR-471, rodovia que liga o município do Chuí ao município de Santa Vitória do Palmar, já estão instalados os primeiros aerogeradores do Complexo Eólico Campos Neutrais, que reúne três grandes parques: Geribatu, Chuí e Hermenegildo. As dez plantas, cada uma com mais de dez aerogeradores do Parque Eólico Geribatu já estão finalizados e em funcionamento, causando uma alteração drástica na fisionomia da paisagem. O objetivo deste trabalho foi compreender, a partir da literatura referente, o crescimento da produção de energia eólica, as características das áreas em que se implantaram parques ou complexos eólicos e os impactos dos objetos técnicos relacionados a esta produção na paisagem. Foi realizado, primeiramente, um levantamento de material bibliográfico sobre os métodos relativos ao estudo da paisagem, destacando-se a abordagem da percepção. Atualmente observa-se que as alterações sentidas na dinâmica do município, devido à instalação do Parque Eólico, não se limitam apenas ao impacto visual, tais como o aumento do fluxo do trânsito e a maior circulação de pessoas. Santa Vitória do Palmar, com a implementação do Parque, vive uma atmosfera de otimismo, ganhando uma nova identidade, alterando assim de forma positiva, a própria relação da comunidade local com o contexto que a circunda. Santa Vitória do Palmar, no imaginário local, passou a contextualizar-se no mundo globalizado através de um símbolo que representa a ideia de desenvolvimento limpo e responsável.

Santa Elena. Ready to reshape its transport energy matrix

Energy Technology Data Exchange (ETDEWEB)

Moreano, Hernan [Universidad Estatal Peninsula de Santa Elena (Ecuador). Inst. de Investigacion Cientifica y Desarrollo Tecnologico (INCYT)

2012-07-01

The renewable energy issue opens the door to an ambient of opportunities. Santa Elena, one of the coastal provinces of Ecuador has the chance to go from a fossil fuel energy culture to a new energy scheme based on the use of environmental friendly fuels like natural gas and other renewable energy carriers like hydrogen. The marginal production of oil and natural gas from the Gustavo Galindo Velasco field and the updated gas reserves from the Gulf of Guayaquil make it possible. Infrastructure for natural gas production and distribution for vehicles is almost ready and any of the three refineries can generate hydrogen from natural gas. This provides the opportunity to reshape the Santa Elena transport energy matrix, where vehicles can burn natural gas and inter country buses can work with hydrogen. Traditional Fishing boats can be fitted with hydrogen storage and fuel systems later on. Santa Elena should face this challenge through a joint effort of public and private parties. Santa Elena State University and its partners as a focus point to create: The Campus of Energy Knowledge, where research, science and technology will serve companies that work in the energy business with a strong synergy, which will create jobs for the Santa Elena people. (orig.)

Association of PTPN22 (rs2476601) and STAT4 (rs7574865) polymorphisms with Rheumatoid Arthritis in the Western Algerian population.

Science.gov (United States)

Fodil, M; Benzaoui, A; Zemani-Fodil, F; Aberkane, M; Boughrara, W; Saidi-Mehtar, N; Petit-Teixeira, E; Boudjema, A

2015-01-01

The aim of the present study was to replicate the association of five risk gene polymorphisms (PTPN22-rs2476601, STAT4-rs7574865, 6q23-rs6927172, IRF5-rs2004640 and TRAF1/C5-rs10818488) with RA in a specific population of the Western Algeria. The study group comprised 110 patients with RA and 197 ethnically matched healthy control subjects. All polymorphisms were genotyped using predesigned TaqMan® assays. Allele and genotype frequencies in patients and control subjects were compared by chi-square test and odds ratios with 95% confidence intervals. Correction for multiple testing was carried out using the Bonferroni adjustment. Statistically significant associations with RA were detected. The strongest signal was obtained for PTPN22-rs2476601 with an allelic Pvalue 3.32 x 10(-11) (OR = 9.83, 95% CI [4.28 - 22.56]). A second significant association was obtained with STAT4-rs7574865 (allelic Pvalue = 4 x 10(-3); OR = 1.75, 95% CI [1.16 - 2.63]). The third SNP, 6q23-rs6927172, showed a significant result of association with RA, but missed our criteria for significance at allelic level after Bonferroni's correction (allelic Pvalue = 0.027; OR = 0.64, 95% CI [0.42 - 0.97]). Finally, IRF5-rs2004640 and TRAF1/C5-rs10818488 showed a significant association only at genotypic level (Pvalues: 3 x 10(-4) and 2.9 x 10(-3) respectively) but did not reach statistical significance when comparing allele frequencies (Pvalues: 0.96 and 0.21 respectively). From this initial study, we can conclude that PTPN22-rs2476601 and STAT4-rs7574865 polymorphisms are clearly associated with the risk of RA in the Western Algerian population.

Association of PTPN22 (rs2476601 and STAT4 (rs7574865 polymorphisms with Rheumatoid Arthritis in the Western Algerian population

Directory of Open Access Journals (Sweden)

Mostefa FODIL

2015-01-01

Full Text Available Aim: The aim of the present study was to replicate the association of five risk gene polymorphisms (PTPN22-rs2476601, STAT4-rs7574865, 6q23-rs6927172, IRF5-rs2004640 and TRAF1/C5-rs10818488 with RA in a specific population of the Western Algeria. Material and methods: The study group comprised 110 patients with RA and 197 ethnically matched healthy control subjects. All polymorphisms were genotyped using predesigned TaqMan® assays. Allele and genotype frequencies in patients and control subjects were compared by chi-square test and odds ratios with 95% confidence intervals. Correction for multiple testing was carried out using the Bonferroni adjustment. Results: Statistically significant associations with RA were detected. The strongest signal was obtained for PTPN22-rs2476601 with an allelic Pvalue 3.32 x 10-11 (OR = 9.83, 95% CI [4.28 – 22.56]. A second significant association was obtained with STAT4-rs7574865 (allelic Pvalue = 4 x 10-3; OR = 1.75, 95% CI [1.16 – 2.63]. The third SNP, 6q23-rs6927172, showed a significant result of association with RA, but missed our criteria for significance at allelic level after Bonferroni’s correction (allelic Pvalue = 0.027; OR = 0.64, 95% CI [0.42 – 0.97]. Finally, IRF5-rs2004640 and TRAF1/C5-rs10818488 showed a significant association only at genotypic level (Pvalues: 3 x 10-4 and 2.9 x 10-3 respectively but did not reach statistical significance when comparing allele frequencies (Pvalues: 0.96 and 0.21 respectively. Conclusions: From this initial study, we can conclude that PTPN22-rs2476601 and STAT4-rs7574865 polymorphisms are clearly associated with the risk of RA in the Western Algerian population.

Effect of Bcl-2 rs956572 polymorphism on age-related gray matter volume changes.

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Mu-En Liu

Full Text Available The anti-apoptotic protein B-cell CLL/lymphoma 2 (Bcl-2 gene is a major regulator of neural plasticity and cellular resilience. Recently, the Bcl-2 rs956572 single nucleotide polymorphism was proposed to be a functional allelic variant that modulates cellular vulnerability to apoptosis. Our cross-sectional study investigated the genetic effect of this Bcl-2 polymorphism on age-related decreases in gray matter (GM volume across the adult lifespan. Our sample comprised 330 healthy volunteers (191 male, 139 female with a mean age of 56.2±22.0 years (range: 21-92. Magnetic resonance imaging and genotyping of the Bcl-2 rs956572 were performed for each participant. The differences in regional GM volumes between G homozygotes and A-allele carriers were tested using optimized voxel-based morphometry. The association between the Bcl-2 rs956572 polymorphism and age was a predictor of regional GM volumes in the right cerebellum, bilateral lingual gyrus, right middle temporal gyrus, and right parahippocampal gyrus. We found that the volume of these five regions decreased with increasing age (all P<.001. Moreover, the downward slope was steeper among the Bcl-2 rs956572 A-allele carriers than in the G-homozygous participants. Our data provide convergent evidence for the genetic effect of the Bcl-2 functional allelic variant in brain aging. The rs956572 G-allele, which is associated with significantly higher Bcl-2 protein expression and diminished cellular sensitivity to stress-induced apoptosis, conferred a protective effect against age-related changes in brain GM volume, particularly in the cerebellum.

Santa soja: narrativa documental em fotolivro

OpenAIRE

Seidl, Eduardo

2016-01-01

A partir do fotolivro Santa Soja como objeto e do resgate histórico das práticas jornalísticas de reportagem e de edição por meio de entrevistas com os cinco autores, esta pesquisa busca identificar o fotolivro como formato potencializador do fotodocumentarismo. Para tanto, foi proposta uma localização conceitual sobre o fotolivro, a linguagem e a narrativa fotográfica e sobre a vocação historiográfica e testemunhal da fotografia, a fim de contextualizar uma análise do fotolivro Santa Soja qu...

Coal bed methane: current status and outlook - Panorama 2008; CBM: bilan et perspectives - Panorama 2008

Energy Technology Data Exchange (ETDEWEB)

NONE

2008-07-01

In many parts of the world, there is growing interest in coal bed methane (CBM), which has been exploited for years in the United States. One reason is undoubtedly that some new gas producing countries, including India and China, are seeking to limit the level of their gas dependence. Another is the need to control greenhouse gas emissions, especially using mechanisms set up under the Kyoto Protocol. Finally, the increase in gas prices on international markets also encourages this trend.

Santa Cruz thermic plant islanding with local loads

Energy Technology Data Exchange (ETDEWEB)

Nascimento, A R [Light Servicos de Eletricidade SA, Rio de Janeiro, RJ (Brazil); Gomes, Paulo; Almeida, Paulo C. de [ELETROBRAS, Rio de Janeiro, RJ (Brazil); Sereno, Marcos G [FURNAS, Rio de Janeiro, RJ (Brazil)

1988-12-31

This work looks into the feasibility of implementing a scheme for the islanding of the Santa Cruz Thermic Plant ( Rio de janeiro State) with LIGHT`s (Electric power public utility) loads fed by the Santa Cruz-Jacarepagua trunk connection, considering presently-existing system problems relative to a significant frequency drop when a loss occurs of a large generation block and which causes the blockade scheme of the mentioned Plant to work, thus aggravating the frequency control still further. An analysis is made of such scheme implementation implications on the scheme for islanding a Santa Cruz 84 MW machine to provide supply to the auxiliary services of The Angra dos Reis nuclear plant presently existing in the system. 2 refs., 9 figs.

Pentatomids associated with different forest species in Itaara, RS, Brazil

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Ervandil Corrêa Costa

2010-03-01

Full Text Available The objective of this study was to determine qualitatively and quantitatively the pentatomid fauna associated with the canopy of different native species during the period from September 2005 to September 2006. Insects were collected from among nine botanical species: Gochnatia polymorpha (Less. (cambará, Eugenia uniflora Berg. (pitangueira, Acca selowiana (Berg Burret (goiaba-da-serra, Psidium cattleianum Sabine (araçá, Baccharis spp., Solanaum mauritianum Scop. (fumo-bravo, Micanea cinerascens Miq. (passiquinho, Calliandra brevipes Bhent. (caliandra, and Schinus molle L. (aroeira located at Rodolfo da Costa Dam in Itaara, RS, Brazil. Samples were taken every two weeks with a conical funnel made of tin plate (2mm, 70cm in diameter at the rim and 63cm in height. One sample per botanical species for each sampling date was taken, by shaking the branches, ten times over the funnel. Samples were sent to the Entomology Laboratory of the Crop Protection Department of the Federal University of Santa Maria, where the material was analyzed. A total of nine Pentatomidae species were identified. Edessa rufomarginata (De Geer, 1773 was the species of highest ocurrence followed by Thyanta humilis (Bergroth, 1891. The botanical species S. mauritianum presented the greatest number of Pentatomidae species, with an occurrence of 26.9%.

Technical Adequacy of the easyCBM Primary-Level Mathematics Measures (Grades K-2), 2009-2010 Version. Technical Report #1006

Science.gov (United States)

Anderson, Daniel; Lai, Cheng-Fei; Nese, Joseph F. T.; Park, Bitnara Jasmine; Saez, Leilani; Jamgochian, Elisa; Alonzo, Julie; Tindal, Gerald

2010-01-01

In the following technical report, we present evidence of the technical adequacy of the easyCBM[R] math measures in grades K-2. In addition to reliability information, we present criterion-related validity evidence, both concurrent and predictive, and construct validity evidence. The results represent data gathered throughout the 2009/2010 school…

Time and position resolution of high granularity, high counting rate MRPC for the inner zone of the CBM-TOF wall

CERN Document Server

Petriş, M.

2016-09-13

Multi-gap RPC prototypes with readout on a multi-strip electrode were developed for the small polar angle region of the CBM-TOF subdetector, the most demanding zone in terms of granularity and counting rate. The prototypes are based on low resistivity ($\\sim$10$^{10}$ $\\Omega$cm) glass electrodes for performing in high counting rate environment. The strip width/pitch size was chosen such to fulfill the impedance matching with the front-end electronics and the granularity requirements of the innermost zone of the CBM-TOF wall. The in-beam tests using secondary particles produced in heavy ion collisions on a Pb target at SIS18 - GSI Darmstadt and SPS - CERN were focused on the performance of the prototype in conditions similar to the ones expected at SIS100/FAIR. An efficiency larger than 98\\% and a system time resolution in the order of 70~-~80~ps were obtained in high counting rate and high multiplicity environment.

Genetic errors of the human caspase recruitment domain-B-cell lymphoma 10-mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (CBM) complex: Molecular, immunologic, and clinical heterogeneity.

Science.gov (United States)

Pérez de Diego, Rebeca; Sánchez-Ramón, Silvia; López-Collazo, Eduardo; Martínez-Barricarte, Rubén; Cubillos-Zapata, Carolina; Ferreira Cerdán, Antonio; Casanova, Jean-Laurent; Puel, Anne

2015-11-01

Three members of the caspase recruitment domain (CARD) family of adaptors (CARD9, CARD10, and CARD11) are known to form heterotrimers with B-cell lymphoma 10 (BCL10) and mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (MALT1). These 3 CARD-BCL10-MALT1 (CBM) complexes activate nuclear factor κB in both the innate and adaptive arms of immunity. Human inherited defects of the 3 components of the CBM complex, including the 2 adaptors CARD9 and CARD11 and the 2 core components BCL10 and MALT1, have recently been reported. Biallelic loss-of-function mutant alleles underlie several different immunologic and clinical phenotypes, which can be assigned to 2 distinct categories. Isolated invasive fungal infections of unclear cellular basis are associated with CARD9 deficiency, whereas a broad range of clinical manifestations, including those characteristic of T- and B-lymphocyte defects, are associated with CARD11, MALT1, and BCL10 deficiencies. Interestingly, human subjects with these mutations have some features in common with the corresponding knockout mice, but other features are different between human subjects and mice. Moreover, germline and somatic gain-of-function mutations of MALT1, BCL10, and CARD11 have also been found in patients with other lymphoproliferative disorders. This broad range of germline and somatic CBM lesions, including loss-of-function and gain-of-function mutations, highlights the contribution of each of the components of the CBM complex to human immunity. Copyright © 2015 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Minimal disturbance : Ensign's ADR-1000-CT rig aimed at CBM market

International Nuclear Information System (INIS)

Roche, P.

2005-01-01

Ensign Resource Services Group Inc. has recently designed a light, mobile rig aimed at Western Canada's coalbed methane (CBM) market. With a 1000 metre depth rating, the automated ADR-1000-CT rig can drill with either jointed pipe or 3 and a half-inch coil. Tractor units are used to move the rig to avoid the extra traffic generated by third-party trucks. The rig's self-levelling capability creates less environmental disturbance. Each component works on sites with as much as 2 metres difference in elevation, which reduces the need for earth-moving equipment. As drilling moves closer to farms and acreages, minimal environmental disturbance is crucial to the CBM industry. The rig won a 2005 Alberta government award for innovations in workplace health and safety as the design eliminates many of the tasks where injuries occur on conventional rigs. On conventional rigs, drill-strings are suspended from a travelling block which is suspended from the crown of a large, heavy derrick. With the ADR, hydraulic cylinders bear the weight of the drill string, and the derrick serves mainly to guide the top drive. When drilling only with jointed pipe, the coiled-tubing reel is a separate load so that drilling crews don't have to transport it around on programs requiring only jointed pipe. If coil is needed, the reel can be trucked to the site and plugged in to the rest of the rig. Tubing is expected to last 3 times as long as on a regular coiled-tubing rig, as the reel is positioned directly over the rotary table. The rigs have been used for various drilling projects and have performed satisfactorily with high penetration rates due to their large mud pumps. It was concluded that the ADR-1000-CT rig's hydraulic self-levelling capability and agility are helpful features when drilling in a minimal disturbance environment. 3 figs

"Santa Maria" forever : Eesti ja Portugali kirjandussuhetest / Toomas Haug

Index Scriptorium Estoniae

Haug, Toomas, 1956-

2012-01-01

Jaanuaris 1961 Portugali diktaatorlikule režiimile protestiks kaaperdatud laevast "Santa Maria", mis sai omamoodi vabaduse ja vastuhaku sümboliks ka okupeeritud Eestis. Artiklis käsitletakse sellest sündmusest mõjutatud teoseid, täpsemalt Aleksander Suumanni maali "Santa Maria" ja Paul-Eerik Rummo samanimelist luuletust

"Santa Maria" forever : Eesti ja Portugali kirjandussuhetest / Toomas Haug

Index Scriptorium Estoniae

Haug, Toomas, 1956-

2015-01-01

Jaanuaris 1961 Portugali diktaatorlikule režiimile protestiks kaaperdatud laevast "Santa Maria", mis sai omamoodi vabaduse ja vastuhaku sümboliks ka okupeeritud Eestis. Artiklis käsitletakse sellest sündmusest mõjutatud teoseid, täpsemalt Aleksander Suumanni maali "Santa Maria" ja Paul-Eerik Rummo samanimelist luuletust

Performance of InsCor and three international scores in cardiac surgery at Santa Casa de Marília.

Science.gov (United States)

Tiveron, Marcos Gradim; Bomfim, Helton Augusto; Simplício, Maycon Soto; Bergonso, Marcos Henriques; Matos, Milena Paiva Brasil de; Ferreira, Sergio Marques; Pelloso, Eraldo Antônio; Barros, Rubens Tofano de

2015-01-01

To apply and to compare the Society of Thoracic Surgery score (STS), EuroSCORE (Eurosc1), EuroSCORE II (Eurosc2) and InsCor (IS) for predicting mortality in patients undergoing to coronary artery bypass graft and/or valve surgery at the Santa Casa Marilia. The present study is a cohort. It is a prospective, observational, analytical and unicentric. We analyzed 562 consecutive patients coronary artery bypass graft and/or valve surgery, between April 2011 and June 2013 at the Santa Casa Marilia. Mortality was calculated for each patient through the scores STS, Eurosc1, Eurosc2 and IS. The calibration was calculated using the Hosmer Lemeshow test and discrimination by ROC curve. The hospital mortality was 4,6%. The calibration is generally adequate group P=0.345, P=0.765, P=0.272 and P=0.062 for STS, Eurosc1, Eurosc2, and IS respectively. The discriminatory power of STS score 0.649 (95% CI 0.529 to 0.770, P=0.012), Eurosc1 0.706 (95% CI 0.589 to 0.823, P ≤0.001), Eurosc2 was 0.704 (95% CI 0.590-0.818 P=0.001) and InsCor 0.739 (95% CI 0.638 to 0.839, P ≤0.001). We can say that overall, the InsCor was the best model, mainly in the discrimination of the sample. The InsCor showed good accuracy, in addition to being effective and easy to apply, especially by using a smaller number of variables compared to the other models.

Electron/pion identification in the CBM TRD using a multilayer perceptron

International Nuclear Information System (INIS)

Akishina, E.P.; Akishina, T.P.; Ivanov, V.V.; Maevskaya, A.I.; Afanas'ev, O.A.

2008-01-01

The problem of electron/pion identification in the CBM experiment based on the measurements of energy losses and transition radiation in the TRD detector is discussed. A possibility to solve such a problem by applying an artificial neural network (ANN) is considered. As input information for the network we used both the samples of energy losses of pions or electrons in the TRD absorbers and the 'clever' variable obtained on the basis of the original data. We show that usage of this new variable permits one to reach a reliable level of particle recognition no longer than after 10-20 training epochs; there are practically no fluctuations against the trend, and the needed level of pions suppression is obtained under the condition of a minimal loss of electrons

Santa Gertrudis : Pétroglifo

OpenAIRE

Puaux , Olivier

1986-01-01

Las Milpillas ( site n°95 ), Santa Gertrudis, Municipio de Zacapu, Michoacán. Opéración 1. Groupo B. Estructura B1. Unidad Excavación Noroeste. Pétroglifo dibajo de los escombros, Fachaba Escalinatas. Coordenadas : 19°51'48" 101°49'.

Alterações Geomorfológicas Derivadas Da Intervenção De Atividades Antrópicas: análise temporal na Bacia do Arroio Santa Bárbara – Pelotas (RS.

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Adriano Luís Heck Simon

2008-11-01

Full Text Available A análise temporal das alterações nas formas do relevo, tendo como base informações espaciais oriundas da cartografia geomorfológica, possibilita a compreensão da gênese dos distúrbios na morfodinâmica e dos impactos ambientais. Assim, este artigo foi desenvolvido com o objetivo de analisar as principais alterações geomorfológicas desencadeadas na bacia do Arroio Santa Bárbara, localizada no município de Pelotas – RS, durante 41 anos (1965 – 2006. Para avaliar as alterações ocorridas sobre a morfologia, foram elaborados mapas geomorfológicos da área em estudo, referentes aos anos de 1965 e 1995, a partir da interpretação de fotografias aéreas. O cenário de 2006 foi constituído por meio de representações cartográficas, esquematizadas a partir da obtenção de imagens orbitais do software Google Earth TM. A integralização deste mapeamento ocorreu por meio de trabalhos de campo, onde foram constatadas as transformações da morfologia e as feições geomorfológicas artificiais. As atividades antrópicas efetivaram a imposição de mecanismos de controle que alteraram as formas e a estrutura do sistema, agindo, conseqüentemente, sobre os fluxos de matéria e energia. Tais alterações vinculam-se à expansão urbana, ao desenvolvimento das atividades agrícolas e às ações antrópicas pontuais como a mineração e a interceptação dos cursos de água para a construção de reservatórios.

The NC3Rs gateway: Accelerating scientific discoveries with new 3Rs models and technologies.

Science.gov (United States)

Percie du Sert, Nathalie; Robinson, Vicky

2018-01-01

This editorial introduces the NC3Rs gateway, which publishes articles and reviews on new models and technologies emerging from NC3Rs-funded research. The aim is to raise awareness about these approaches, increase confidence in their capability, and provide sufficient information to facilitate their uptake by others.

Le culte de Santa Librada à Sigüenza: Patronage urbain et emblématique impériale

Directory of Open Access Journals (Sweden)

Gélis, Jacques

1996-06-01

Full Text Available After the reconquest of Sigüenza in 1124, St. Librada became the town's patron saint. Legend has it that she was born out of a múltiple delivery and that, because of her christian faith, her father had her die together with her eight sisters. On the iconography of her martyrdom, one of the representations is that of the crucified «strong virgin»; the other, more conventional, is on a plateresque altarpiece which honors her memory in Sigüenza's cathedral, a donation by a bishop close to Charles V. Behind these representations lies the complex relationship among the saint, the town's inhabitants, the church and, beginning from the l6th century, the state. St. Librada was then associated with Hercules, Charles V's favorite hero, in the defense of the sovereign's political interests.Reconquistada Sigüenza en 1124, Santa Librada se constituye en patrona de la ciudad. La leyenda la hace renacer de un parto múltiple y morir con sus ocho hermanas, por voluntad de su padre, por ser cristiana. Dos son las iconografías existentes de su martirio, una es la de «virgen fuerte» crucificada, la otra con la palma; y un retablo plateresco, donación de un prelado próximo a Carlos V, celebra su memoria en la catedral seguntina. Detrás de estas representaciones, se adivina la compleja relación entre la protectora, los habitantes de la ciudad, la Iglesia y, a partir de comienzos del siglo XVI, el Estado. Santa Librada fue entonces relacionada con Hércules, el héroe predilecto de Carlos V, en defensa de los intereses políticos del soberano.

J/ψ reconstruction in the di-muon decay channel with the CBM experiment for p+Au collisions at 30 GeV laboratory beam energy

International Nuclear Information System (INIS)

Akishina, V; Kisel, I

2013-01-01

The study of p+Au collisions at 30 GeV laboratory beam energy is considered as a part of the CBM research program and will be performed in the first phase of FAIR with a start version of the CBM detector at SIS-100. Results of J/ψ reconstruction feasibility studies in di-muon channel in proton-nuclear collisions at SIS 100 energies are presented. The simulated detector concept includes STS and MuCh detectors. The study was performed for a wide range of MuCh detector inefficiency. Also the influence of MuCh stations misalignment on the charmonium reconstruction efficiency was studied. The algorithm allows to reconstruct J/ψ with an efficiency of 31.3 % and the signal to the background ratio of 24.4.

Avaliação histológica dos testículos de ovinos da raça Santa Inês nascidos em diferentes estações do ano Histological evaluation of Santa Ines sheep testicles born in different seasons

Directory of Open Access Journals (Sweden)

Concepta McManus

2010-02-01

Full Text Available Foram analisados quatro grupos de ovinos machos da raça Santa Inês nascidos em quatro estações do ano, no Distrito Federal, a fim de observar as idades e o peso corporal em que estes atingiram a puberdade. A partir dos cortes histológicos dos testículos, foram analisados parâmetros celulares e mensurações dos túbulos seminíferos. O efeito da data de nascimento sobre os parâmetros avaliados foi significativo (PFour groups of Santa Inês male sheep born in four seasons in the Distrito Federal were analyzed to evaluate the age and body weight at puberty, at which point were castrated. Histological measurements were carried out on the testicles to evaluate cellular parameters and size measurements of the seminiferous tubules. The effect of the group on cellular parameters was significant (P<0.01. Animals born in the dry season were more precocious than the others, but showed the worst histological profile of the testis. The histological traits of the testis of the Santa Inês rams were influenced by the season. The end of the rainy season was shown to the best season for births of sheep in the Central region of Brazil, with histological testicular traits at puberty being superior to the other groups.

Polymorphism of angiotensin-converting enzyme (rs4340 and diabetic nephropathy in Caucasians with type 2 diabetes mellitus

Directory of Open Access Journals (Sweden)

Šeruga M

2016-12-01

Full Text Available Diabetic nephropathy (DN is the leading cause of endstage renal disease (ESRD in developed countries. Several environmental and genetic factors predict the development and progression of DN. The renin-angiotensin system was demonstrated to be involved in the development of DN. We evaluated the association between rs4340 of the angiotensin-converting enzyme (ACE gene and DN in Caucasians with type 2 diabetes mellitus (T2DM in 276 Slovenian patients with T2DM who had DN, and 375 patients without clinical signs of DN. Genetic analysis was performed with either standard polymerase chain reaction (PCR (for rs4340. Results were analyzed using the χ2 test and multivariate logistic regression analyses. We found no association between rs4340 and DN. Cystatin C was significantly higher in the DN+ group (p <0.001 than in the DN group. Cystatin C was a better marker for the estimation of renal function than estimated glomerular filtration rate (eGFR according to the modification diet in renal disease (MDRD equation mL/ min. We concluded that there was no association between the rs4340 of the ACE gene and DN in Caucasian patients who have T2DM.

Association Between rs1344706 of ZNF804A and Schizophrenia: A Meta-analysis

Directory of Open Access Journals (Sweden)

Meiyan Zhu

2014-12-01

Full Text Available Schizophrenia is one of the most serious mental diseases found in humans. Previous studies indicated that the single nucleotide polymorphism (SNP rs1344706 in the gene ZNF804A encoding zinc finger protein 804A was associated with schizophrenia in Caucasian population but not in Chinese Han population. However, current results are conflicting in Asian population. In the present study, a meta-analysis was performed to revisit the association between rs1344706 and the risk of schizophrenia in Asian, Caucasian and other populations. Electronic search of PubMed database identified 25 case–control studies with available genotype frequencies of rs1344706 for the meta-analysis, involving a total of 15,788 cases and 22,654 controls. A pooled odds ratio (OR with 95% confidence interval (CI was used to assess the association. The current meta-analysis showed an association between rs1344706 and schizophrenia in Caucasian populations (P = 0.028, OR = 1.138, 95% CI: 1.014–1.278; P = 0.004 for heterogeneity and Asian populations (P = 0.008, OR = 1.092, 95% CI: 1.023–1.165; P = 0.001 for heterogeneity, but not in other populations (P = 0.286, OR = 1.209, 95% CI: 0.853–1.714, P = 0.120 for heterogeneity. Egger’s test (P > 0.05 and Begg’s test (P > 0.05 are both suggestive of the lack of publication bias for the included studies. Thus, the absence of association in other populations suggests a genetic heterogeneity in the susceptibility of schizophrenia and demonstrates the difficulties in replicating genome-wide association study findings regarding schizophrenia across different ethnic populations. To validate the association between rs1344706 and schizophrenia, further studies with larger participant populations worldwide are needed.

HLA variants rs9271366 and rs9275328 are associated with systemic lupus erythematosus susceptibility in Malays and Chinese.

Science.gov (United States)

Chai, H C; Phipps, M E; Othman, I; Tan, L P; Chua, K H

2013-02-01

Human leukocyte antigen (HLA) antigens and genes have long been reported associated with systemic lupus erythematosus (SLE) susceptibility in many populations. With the advance in technologies such as genome-wide association studies, many newly discovered SLE-associated single-nucleotide polymorphisms (SNPs) have been reported in recent years. These include HLA-DRB1/HLA-DQA1 rs9271366 and HLA-DQB1/HLA-DQA2 rs9275328. Our aim was to investigate these SNPs in a Malaysian SLE cohort. SNPs rs9271366 and rs9275328 were screened across 790 Malaysian citizens from three ethnic groups (360 patients and 430 healthy volunteers) by Taqman SNP genotyping assays. Allele and genotyping frequencies, Hardy-Weinberg equilibrium, Fisher's exact test and odds ratio were calculated for each SNP and ethnic group. Linkage disequilibrium and interaction between the two SNPs were also evaluated. The minor allele G and its homozygous genotype GG of HLA-DRB1/HLA-DQA1 rs9271366 significantly increased the SLE susceptibility in Malaysian patients, including those of Malay and Chinese ethnicity (odds ratio (OR) > 1, p < 0.05). As for HLA-DQB1/HLA-DQA2 rs9275328, the minor allele T and the heterozygous genotype CT conferred protective effect to SLE in Malaysians, as well as in Malays and Chinese, by having OR < 1 and p value <0.05. Both SNPs did not show associations to SLE in Indians. D' and r (2) values for the two SNPs in LD analysis were 0.941 and 0.065, respectively, with haplotype GC and AT being significantly associated with SLE (p < 5.0 × 10(-4)) after 10,000 permutations were performed. The MDR test clustered the genotype combinations of GG and CC, and AG and CC of rs9271366 and rs9275328, accordingly, as high-risk group, and the two SNPs interacted redundantly by removing 1.96% of the entropy. Our findings suggest that in addition to some classical HLA variants, rs9271366 and rs9275328 are additional polymorphisms worth considering in the Malaysian and possibly in

Evaluation of transcobalamin II rs1801198 and transcobalamin II receptor rs2336573 gene polymorphisms in recurrent spontaneous abortion.

Science.gov (United States)

Hashemi, Mohammad; Mokhtari, Mojgan; Yazdani-Shahrbabaki, Vajiheh; Danesh, Hiva; Bizhani, Fatemeh; Taheri, Mohsen

2018-03-14

It has been proposed that transcobalamin 2 (TCN2) and the transcobalamin 2 receptor (TCN2R) are associated with idiopathic recurrent spontaneous abortion (RSA). The aim of the present study was to investigate the impact of TCN2 rs1801198 and TCN2R rs2336573 polymorphism on RSA in a sample of Iranian population. This case-control study was done on 92 RSA patients and 93 normal, fertile women. Genotyping of the TCN2 rs1801198 and TCN2R rs2336573 variants was done by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP). The findings showed no significant association between the TCN2 rs1801198 and TCN2R rs2336573 polymorphisms and the risk/protection of RSA. Our results did not support an association between the TCN2 polymorphism and the risk of RSA in a sample of southeast Iranian population. Larger studies with different ethnicities are needed to evaluate the possible impact of TCN2 and TCN2R polymorphisms on the pathogenesis of RSA. Impact statement What is already known on this subject? Recurrent spontaneous abortion (RSA), a multifactorial condition, is one of the most common complications of pregnancy. It has been proposed that genetic polymorphisms play a role in the pathogenesis of RSA. Few studies have examined the association between TNC2 and TCN2R polymorphisms and the RSA risk and the findings were inconsistent. The aim of the current study was to determine the possible association between the TCN2 rs1801198 and TCN2R rs2336573 polymorphisms and the RSA in a sample of the southeast Iranian population. What do the results of the study add? The findings of the present case-control study did not support an association between the TCN2 rs1801198 and TCN2R rs2336573 polymorphisms and the risk of RSA in a sample of the Iranian population. What are the implications of these findings for clinical practice and future research? The findings of this study may provide a basis for future studies with larger sample sizes and different ethnicities

Quality assurance tests of the CBM silicon tracking system sensors with an infrared laser

Energy Technology Data Exchange (ETDEWEB)

Teklishyn, Maksym [FAIR GmbH, Darmstadt (Germany); KINR, Kyiv (Ukraine); Collaboration: CBM-Collaboration

2016-07-01

Double-sided 300 μm thick silicon microstrip sensors are planned to be used in the Silicon Tracking System (STS) of the future CBM experiment. Different tools, including an infrared laser, are used to induce charge in the sensor medium to study the sensor response. We use present installation to develop a procedure for the sensor quality assurance during mass production. The precise positioning of the laser spot allows to make a clear judgment about the sensor interstrip gap response which provides information about the charge distribution inside the sensor medium. Results are compared with the model estimations.

ST segment/heart rate slope as a predictor of coronary artery disease: comparison with quantitative thallium imaging and conventional ST segment criteria

International Nuclear Information System (INIS)

Finkelhor, R.S.; Newhouse, K.E.; Vrobel, T.R.; Miron, S.D.; Bahler, R.C.

1986-01-01

The ST segment shift relative to exercise-induced increments in heart rate, the ST/heart rate slope (ST/HR slope), has been proposed as a more accurate ECG criterion for diagnosing significant coronary artery disease (CAD). Its clinical utility, with the use of a standard treadmill protocol, was compared with quantitative stress thallium (TI) and standard treadmill criteria in 64 unselected patients who underwent coronary angiography. The overall diagnostic accuracy of the ST/HR slope was an improvement over TI and conventional ST criteria (81%, 67%, and 69%). For patients failing to reach 85% of their age-predicted maximal heart rate, its diagnostic accuracy was comparable with TI (77% and 74%). Its sensitivity in patients without prior myocardial infarctions was equivalent to that of thallium (91% and 95%). The ST/HR slope was directly related to the angiographic severity (Gensini score) of CAD in patients without a prior infarction (r = 0.61, p less than 0.001). The ST/HR slope was an improved ECG criterion for diagnosing CAD and compared favorably with TI imaging

Role of redoximiRs in fibrogenesis.

Science.gov (United States)

Fierro-Fernández, Marta; Miguel, Verónica; Lamas, Santiago

2016-04-01

Fibrosis can be defined as an excessive accumulation of extracellular matrix (ECM) components, ultimately leading to stiffness, scarring and devitalized tissue. MicroRNAs (miRNAs) are short, 19-25 nucleotides (nt), non-coding RNAs involved in the post-transcriptional regulation of gene expression. Recently, miRNAs have also emerged as powerful regulators of fibrotic processes and have been termed "fibromiRs". Oxidative stress represents a self-perpetuating mechanism in fibrogenesis. MiRNAs can also influence the expression of genes responsible for the generation of reactive oxygen species (ROS) and antioxidant defence and are termed "redoximiRs". Here, we review the current knowledge of mechanisms by which "redoximiRs" regulate fibrogenesis. This new set of miRNAs may be called "redoxifibromiRs". Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

O potencial de geração CBM (Coalbed Methane na jazida Sul Catarinense: 1. Características petrográficas e químicas das camadas de carvão da Formação Rio Bonito, Permiano da Bacia do Paraná

Directory of Open Access Journals (Sweden)

Priscila dos Santos Lourenzi

Full Text Available Atualmente, o CBM representa uma importante fonte de energia alternativa. A mais importante sucessão sedimentar portadora de carvão no Brasil ocorre na Bacia do Paraná, com as maiores reservas localizadas nas jazidas do RS e de SC. Este trabalho tem por objetivo analisar as características químicas e petrográficas das camadas de carvão de três poços, realizados recentemente na jazida Sul Catarinense (SC nos municípios de Treviso e Araranguá, com o intuito de avaliar a capacidade de geração de gás metano associado. Foram coletadas amostras de sete camadas de carvão (Barro Branco, Irapuá, A, Bonito Superior, Bonito Inferior, Pré-Bonito Superior e Pré-Bonito Inferior da Formação Rio Bonito que foram submetidas à análise petrográfica e química. O litotipo carvão fosco bandado (BD predominou no CBM-SC-2012, e carvão fosco (D, no CBM-SC-2013. Os resultados petrográficos indicaram valores de 0,60 a 1,26 Rrandom (%, classificando o carvão segundo o rank desde betuminoso alto volátil C até betuminoso médio volátil. A análise de macerais mostra variação na composição das camadas, com predomínio de vitrinita e inertinita. Quanto à análise imediata, as amostras variaram de 34,93 a 65,70% em peso de cinza. O poder calorífico varia de 1858,0 a 5074,8 cal/g. O conteúdo de carbono varia de 4,15 a 65,81%, e o enxofre, de 0,22 a 12,43%. De acordo com os parâmetros analisados, as camadas Barro Branco e Irapuá apresentam as condições necessárias para geração e armazenagem de gás natural, enquanto a camada Bonito apresenta baixo potencial devido ao alto conteúdo de matéria mineral.

Pelas trilhas da ILha de Santa Catarina

OpenAIRE

Silveira, Flavio Leonel Abreu da

1996-01-01

Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciencias Humanas O estudo sobre o ecoturismo na Ilha de Santa Catarina vem demonstrar o surgimento de novas modalidades turísticas entre os grupos urbanos. A pesquisa aponta para a intersecção entre lazer, turismo, ecologia e esporte, demonstrando a importân-cia das práticas ecoturísticas na atualidade. A partir de tal perspectiva, as questões de gênero surgem com significativa relevância. Estamos frente...

Santa Fe Linac Conference

International Nuclear Information System (INIS)

Anon.

1982-01-01

The 1981 Linear Accelerator Conference, organized by Los Alamos National Laboratory, was held from 19-23 October in Santa Fe, New Mexico. The surroundings were superb and helped to ensure a successful meeting. There were more than two hundred and twenty participants, with good representation from Japan and Western Europe

Online 4-dimensional event reconstruction in the CBM experiment

Energy Technology Data Exchange (ETDEWEB)

Akishina, Valentina [Goethe-Universitaet Frankfurt, Frankfurt am Main (Germany); GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Joint Institute for Nuclear Research, Dubna (Russian Federation); Kisel, Ivan [Goethe-Universitaet Frankfurt, Frankfurt am Main (Germany); GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Frankfurt Institute for Advanced Studies, Frankfurt am Main (Germany); Collaboration: CBM-Collaboration

2015-07-01

The heavy-ion experiment CBM will focus on the measurement of rare probes at interaction rates up to 10 MHz with data flow of up to 1 TB/s. The free-running data acquisition, delivering a stream of untriggered detector data, requires full event reconstruction and selection to be performed online not only in space, but also in time. The First-Level Event Selection package consists of several modules: track finding, track fitting, short-lived particles finding, event building and event selection. For track reconstruction the Cellular Automaton (CA) method is used, which allows to reconstruct tracks with high efficiency in a time-slice and perform event building. The time-based CA track finder allows to resolve tracks from a time-slice in event-corresponding groups. The algorithm is intrinsically local and the implementation is both vectorized and parallelized between CPU cores. The CA track finder shows a strong scalability on many-core systems. The speed-up factor of 10.6 on a CPU with 10 hyper-threaded physical cores was achieved.

Efeito do monocultivo de Pinus e da queima do campo nativo em atributos biológicos do solo no Planalto Sul Catarinense Effects of native pasture burning and Pinus monoculture on changes in soil biological attributes on the Southern Plateau of Santa Catarina - Brazil

Directory of Open Access Journals (Sweden)

Dilmar Baretta

2005-10-01

Full Text Available O presente estudo objetivou avaliar o impacto da queima tradicional de campo nativo e do monocultivo de Pinus sp. em Lages (SC, no CO total do solo (COT, carbono da biomassa microbiana (CBM, respiração basal (C-CO2, quociente metabólico microbiano (qCO2 e relação CBM:COT. Foram selecionadas quatro áreas representativas da região, de 0,5 ha cada, sendo: (a Campo nativo, sem queima nos últimos 50 anos (CN; (b Campo nativo submetido à queima tradicional (CNQ, ambas, pastagens naturais; (c Mata natural com predominância de Araucaria angustifolia (MATA; e (d Reflorestamento de Pinus taeda com oito anos (PINUS. Para tanto, coletaram-se seis amostras, compostas de nove subamostras de solo em cada área, na profundidade de 0-5 cm, em dezembro de 2002. Para avaliar o CBM, foi utilizado o método da fumigação-extração. O C-CO2 foi determinado em laboratório. Os maiores valores de liberação de C-CO2 foram encontrados na MATA e no PINUS, seguidos de CNQ e CN, respectivamente. Os maiores valores de CBM, COT e relação CBM:COT foram encontrados na MATA, não tendo as demais áreas estudadas apresentado diferenças entre si. O qCO2 foi maior no PINUS, seguido de CNQ, em comparação com MATA e CN. A análise multivariada mostrou ser uma ferramenta auxiliar importante ao discriminar o CBM como sendo o atributo que mais contribuiu na separação entre as áreas estudadas.The objective of this study was to evaluate the impact of burning native pastures and of cultivating Pinus sp in monoculture in Lages, State of Santa Catarina, Brazil. Total organic carbon (TOC, microbial biomass carbon (MBC, microbial basal respiration (C-CO2, the microbial metabolic quotient (qCO2, and the ratio MBC/TOC were analyzed. Four representative areas of the region with 0.5 ha each were selected: (a native pasture without burning for at least 50 years (NP; (b native pasture burnt off every year (NPF; (c natural forest (NF with predominance of Araucaria angustifolia

Free inside: The Music Class at Santa Ana Jail

Science.gov (United States)

Fierro, Joe

2010-01-01

This article examines the workings of the music class at the Santa Ana Jail in Santa Ana, California. It gives us insight into a jail system and a music class focused on helping inmates position themselves to become productive members of society. In this article I examine how the facility encourages inmates' good behaviour and why the music class…

Polymorphism of rs7688672 and rs10033237 in cGKII/PRKG2 and gout susceptibility of Han population in northern China.

Science.gov (United States)

Guo, Min; Cheng, Zhifeng; Li, Changgui; Li, Shanshan; Li, Ming; Wang, Mingli; Xu, Jinmei; Tang, Yingying; Wang, Yujing; Qiu, Wenli; Liu, Xiaomin

2015-05-10

Gout is a genetic or acquired metabolic disease caused by increase of uric acid synthesis resulted from purine metabolic abnormalities. Whether cGMP-dependent protein kinase 2 (cGKII/PRKG2) is correlated with gout remains controversial. The objective of the present study was to investigate whether there is a correlation between polymorphism of cGKII/PRKG2 and gout susceptibility of Han population in northern China. Four hundred and five male patients with gout in the case group and 429 controls in the control group were collected from the Department of Endocrinology and Metabolic Disease, the Fourth Affiliated Hospital of Harbin Medical University. A case-control study method was used to study the correlation between cGKII/PRKG2 polymorphism rs7688672 and rs10033237 and gout susceptibility. The genotype frequencies of rs7688672 and rs10033237 polymorphisms of cGKII/PRKG2 in the case group and the control group both were in accordance with Hardy-Weinberg equilibrium. There were significant differences of rs10033237 in the allele frequencies and genotype distributions (Pgout. Combined mutation sites AA(*) from rs7688672 and rs10033237 were negatively correlated with gout susceptibility, whereas haplotype GG(*) was positively correlated with gout susceptibility. In conclusion, patients with rs10033237 polymorphism of cGKII/PRKG2 gene are more likely to suffer from gout. With regard to haplotypes of rs10033237 and rs7688672, both AA(*) and GG(*) are related to gout. AA(*) is a gout susceptible gene, whereas GG(*) is a protective gene. Copyright © 2015 Elsevier B.V. All rights reserved.

The Silicon Tracking System of the CBM experiment at FAIR

Directory of Open Access Journals (Sweden)

Teklishyn Maksym

2018-01-01

Full Text Available The Silicon Tracking System (STS is the central detector in the Compressed Baryonic Matter (CBM experiment at FAIR. Operating in the 1Tm dipole magnetic field, the STS will enable pile-up free detection and momentum measurement of the charged particles originating from beam-target nuclear interactions at rates up to 10 MHz. The STS consists of 8 tracking stations based on double-sided silicon micro-strip sensors equipped with fast, self-triggering read-out electronics. With about two million read-out channels, the STS will deliver a high-rate stream of time-stamped data that is transferred to a computing farm for on-line event determination and analysis. The functional building block is a detector module consisting of a sensor, micro-cables and two front-end electronics boards. In this contribution, the development status of the STS components and the system integration is discussed and an outlook on the detector construction is given.

4D Cellular Automaton Track Finder in the CBM Experiment

International Nuclear Information System (INIS)

Akishina, Valentina; Kisel, Ivan

2016-01-01

The CBM experiment (FAIR/GSI, Darmstadt, Germany) will focus on the measurement of rare probes at interaction rates up to 10MHz with data flow of up to 1 TB/s. It requires a novel read-out and data-acquisition concept with self-triggered electronics and free-streaming data. In this case resolving different collisions is a non-trivial task and event building must be performed in software online. That requires full online event reconstruction and selection not only in space, but also in time, so-called 4D event building and selection. This is a task of the First-Level Event Selection (FLES). The FLES reconstruction and selection package consists of several modules: track finding, track fitting, short-lived particles finding, event building and event selection. The Cellular Automaton (CA) track finder algorithm was adapted towards time-based reconstruction. In this article, we describe in detail the modification done to the algorithm, as well as the performance of the developed time-based CA approach

Deriving the effective focal plane for the CBM-RICH detector

Energy Technology Data Exchange (ETDEWEB)

Kres, Ievgenii [Wuppertal University (Germany); Collaboration: CBM-Collaboration

2016-07-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR complex will investigate the phase diagram of strongly interacting matter at high baryon density and moderate temperatures in A+A collisions from 2-11 AGeV (SIS100). A central component of the proposed detector setup is a ring imaging Cherenkov detector (RICH) using CO2 as radiator gas, and a focussing optic with a large spherical mirror. In the present design, the optimal focal plane is approximated using four individual, flat detection surfaces. However, the exact shape and position of the ideal focal plane is subject to further optimization due to effects from tilting the focussing mirror and from momentum dependant deflection of the electron tracks in the magnetic stray field. In this talk, we present a new approach to derive the effective 3-dimensional shape of the focal plane based on a set of Monte Carlo simulations, comparing the ring sharpness at each point of a preliminary focal plane as function of z-position.

Noteworthy bird records at Lagoa Santa, southeastern Brazil Registros notáveis de aves em Lagoa Santa, sudeste do Brasil

OpenAIRE

Marcos Rodrigues

2008-01-01

Lagoa Santa, a small town in southeastern Brazil where naturalist Peter Lund lived, is regarded nowadays as an important historical site for the biological sciences. From 1847 to 1855, J.T. Reinhardt, hosted by Lund, collected 343 bird species. This material is an outstanding reference for many modern ornithological studies. The present paper reports the occurrence of some rare and threatened birds for the region of Lagoa Santa between 1998 and 2005. In this account I list the Rusty-margined ...

[Genetic Variability and Structure of SNP Haplotypes in the DMPK Gene in Yakuts and Other Ethnic Groups of Northern Eurasia in Relation to Myotonic Dystrophy].

Science.gov (United States)

Swarovskaya, M G; Stepanova, S K; Marussin, A V; Sukhomyasova, A L; Maximova, N R; Stepanov, V A

2015-06-01

The genetic variability of the DMPK locus has been studied in relation to six SNP markers (rs2070736, rs572634, rs1799894, rs527221, rs915915, and rs10415988) in Yakuts with myotonic dystrophy (MD) in the Yakut population and in populations of northern Eurasia. Significant differences were observed in the allele frequencies between patients and a population sample of Yakuts for three SNP loci (rs915915, rs1799894, and rs10415988) associated with a high chance of disease manifestation. The odds ratios (OR) of MD development in representatives of the Yakut population for these three loci were 2.59 (95% CI, p = 0,004), 4.99 (95% CI, p = 0.000), and 3.15 (95% CI, p = 0.01), respectively. Haplotype TTTCTC, which is associated with MD, and haplotype GTCCTT, which was observed only in Yakut MD patients (never in MD patients of non-Yakut origin), were revealed. A low level of variability in the locus of DMRK gene in Yakuts (H(e) = 0.283) compared with other examined populations was noted. An analysis of pairwise genetic relationships between populations revealed their significant differentiation for all the examined loci. In addition, a low level of differentiation in territorial groups of Yakut populations (F(ST) = 0.79%), which was related to the high subdivision of the northern Eurasian population (F(ST) = 11.83%), was observed.

The Two-Component System CprRS Senses Cationic Peptides and Triggers Adaptive Resistance in Pseudomonas aeruginosa Independently of ParRS

DEFF Research Database (Denmark)

Fernandez, Luca; Jenssen, Håvard; Bains, Manjeet

2012-01-01

dependency on the CprRS and ParRS systems in a concentration-dependent manner. It was further demonstrated that, following exposure to inducing antimicrobial peptides, cprRS mutants did not become adaptively resistant to polymyxins as was observed for wild-type cells. Our microarray studies demonstrated...

California State Waters Map Series: offshore of Santa Barbara, California

Science.gov (United States)

Johnson, Samuel Y.; Dartnell, Peter; Cochrane, Guy R.; Golden, Nadine E.; Phillips, Eleyne L.; Ritchie, Andrew C.; Greene, H. Gary; Krigsman, Lisa M.; Kvitek, Rikk G.; Dieter, Bryan E.; Endris, Charles A.; Seitz, Gordon G.; Sliter, Ray W.; Erdey, Mercedes D.; Gutierrez, Carlos I.; Wong, Florence L.; Yoklavich, Mary M.; Draut, Amy E.; Hart, Patrick E.; Conrad, James E.; Cochran, Susan A.; Johnson, Samuel Y.; Cochran, Susan A.

2013-01-01

In 2007, the California Ocean Protection Council initiated the California Seafloor Mapping Program (CSMP), designed to create a comprehensive seafloor map of high-resolution bathymetry, marine benthic habitats, and geology within the 3-nautical-mile limit of California’s State Waters. The CSMP approach is to create highly detailed seafloor maps through collection, integration, interpretation, and visualization of swath sonar data, acoustic backscatter, seafloor video, seafloor photography, high-resolution seismic-reflection profiles, and bottom-sediment sampling data. The map products display seafloor morphology and character, identify potential marine benthic habitats, and illustrate both the surficial seafloor geology and shallow (to about 100 m) subsurface geology. The Offshore of Santa Barbara map area lies within the central Santa Barbara Channel region of the Southern California Bight. This geologically complex region forms a major biogeographic transition zone, separating the cold-temperate Oregonian province north of Point Conception from the warm-temperate California province to the south. The map area is in the southern part of the Western Transverse Ranges geologic province, which is north of the California Continental Borderland. Significant clockwise rotation—at least 90°—since the early Miocene has been proposed for the Western Transverse Ranges province, and geodetic studies indicate that the region is presently undergoing north-south shortening. Uplift rates (as much as 2.2 mm/yr) that are based on studies of onland marine terraces provide further evidence of significant shortening. The city of Santa Barbara, the main coastal population center in the map area, is part of a contiguous urban area that extends from Carpinteria to Goleta. This urban area was developed on the coalescing alluvial surfaces, uplifted marine terraces, and low hills that lie south of the east-west-trending Santa Ynez Mountains. Several beaches line the actively

Technology spurs growth of U.S. coalbed methane

International Nuclear Information System (INIS)

Stevens, S.H.; Kuuskraa, J.A.; Schraufnagel, R.A.

1996-01-01

Since the late 1980s, more than $2 billion in capital investments and continued technological advances have harnessed an entirely new source of natural gas -- coalbed methane (CBM). From its roots as an experimental coal mine degasification method, the CBM industry today has grown into significant component of US natural gas supply. This report, the second of a four part series assessing unconventional gas development in the US, examines the state of the CBM industry following the 1992 expiration of the Sec. 29 Nonconventional Fuels Tax Credit. Parts of the industry believed that CBM was largely a tax credit play that would die out once supports were removed. Now that several years have passed, however, it is becoming clear that the CBM industry has legs sturdy enough to carry it into the 21st century without special tax breaks. This article presents the post 1992 drilling and production data, coupled with detailed assessments of specific CBM projects, which together paint a portrait of a CBM industry that overall continues to thrive without tax credits, thanks to improving E and P technology and continued identification of favorable reservoir settings

USB and RS232 voltage datalogger

Directory of Open Access Journals (Sweden)

Lorenzo Hernández Tabares

2011-01-01

Full Text Available Normal 0 21 false false false MicrosoftInternetExplorer4 st1:*{behavior:url(#ieooui } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} The design and construction of a PIC microcontroller based datalogger with USB 2.0 and RS232 interfaces is presented. The datalogger has one 0 to +10VDC analogue input, 10bits ADC, Real Time Clock, 4k sample room on the microcontroller’s program flash memory and an external DC power supply. This paper proposes a cheap variant to construct such device widely used in meteorological and environmental instrumentation among others. The prototype was attached to an Ultraviolet Photometric O3 Analyzer for recording the environmental (tropospheric ozone concentration in a control station at the Havana city. Key words: datalogger, USB, enviromental ozone

Sediment Dynamics Affecting the Threatened Santa Ana Sucker in the Highly-modified Santa Ana River and Inset Channel, Southern California, USA

Science.gov (United States)

Minear, J. T.; Wright, S. A.

2015-12-01

In this study, we investigate the sediment dynamics of the low-flow channel of the Santa Ana River that is formed by wastewater discharges and contains some of the last remaining habitat of the Santa Ana Sucker (Catostomus santaanae). The Santa Ana River is a highly-modified river draining the San Bernardino Mountains and Inland Empire metropolitan area east of Los Angeles. Home to over 4 million people, the watershed provides habitat for the federally-threatened Santa Ana Sucker, which presently reside within the mainstem Santa Ana River in a reach supported by year-round constant discharges from water treatment plants. The nearly constant low-flow wastewater discharges and infrequent runoff events create a small, approximately 8 m wide, inset channel within the approximately 300 m wide mainstem channel that is typically dry except for large flood flows. The sediment dynamics within the inset channel are characterized by constantly evolving bed substrate and sediment transport rates, and occasional channel avulsions. The sediment dynamics have large influence on the Sucker, which rely on coarse-substrate (gravel and cobble) for their food production. In WY 2013 through the present, we investigated the sediment dynamics of the inset channel using repeat bathymetric and substrate surveys, bedload sampling, and discharge measurements. We found two distinct phases of the inset channel behavior: 1. 'Reset' flows, where sediment-laden mainstem discharges from upstream runoff events result in sand deposition in the inset channel or avulse the inset channel onto previously dry riverbed; and 2. 'Winnowing' flows, whereby the sand within the inset channel is removed by clear-water low flows from the wastewater treatment plant discharges. Thus, in contrast to many regulated rivers where high flows are required to flush fine sediments from the bed (for example, downstream from dams), in the Santa Ana River the low flows from wastewater treatment plants serve as the flushing

The electrocardiographic "triangular QRS-ST-T waveform" pattern in patients with ST-segment elevation myocardial infarction: Incidence, pathophysiology and clinical implications.

Science.gov (United States)

Cipriani, Alberto; D'Amico, Gianpiero; Brunello, Giulia; Perazzolo Marra, Martina; Migliore, Federico; Cacciavillani, Luisa; Tarantini, Giuseppe; Bauce, Barbara; Iliceto, Sabino; Corrado, Domenico; Zorzi, Alessandro

A specific ECG pattern of presentation of ST-segment elevation acute myocardial infarction (STEMI), characterized by "triangular QRS-ST-T waveform" (TW), has been associated with poor in-hospital prognosis but longitudinal data on its incidence and clinical impact are lacking. We prospectively evaluated the incidence and prognostic meaning of the TW pattern in a cohort of consecutive STEMI patients. All STEMI patients who presented within 12h of symptoms onset and showed no complete bundle branch block or paced ventricular rhythm were included. The TW pattern was defined as a unique, giant wave (amplitude≥1mV) resulting from the fusion of the QRS complex, the ST-segment and the T-wave and showing a "triangular" morphology with a positive polarity in the leads exploring the ischemic region. Among 428 consecutive STEMI patients, 367 fulfilled the enrollment criteria. The TW pattern was identified in 5 of 367 patients (1.4%) on the admission ECG. This subset of STEMI patients with TW pattern significantly more often showed a left main coronary artery involvement (2/4, 50% vs 2/322, 0.6%; p<0.001), experienced ventricular fibrillation (5/5, 100% vs 35/362, 9.6% p<0.001), had cardiogenic shock (4/5, 80% vs. 14/362, 3.8%, p<0.001) and died during hospitalization (2/5, 40% vs 15/362, 4.1% p=0.02), compared with those with other ST-segment elevation ECG patterns. The TW pattern is an uncommon ECG finding, which reflects the presence of a large area of transmural myocardial ischemia and predicts cardiogenic shock accounting for high in-hospital mortality. When present, this ECG pattern should prompt aggressive therapeutic strategies, including mechanical support of circulation. Copyright © 2017 Elsevier Inc. All rights reserved.

Gaining momentum : advanced multilateral technology touted as key to unlocking Manville CBM

International Nuclear Information System (INIS)

Smith, M.

2006-01-01

A new technology developed by a Louisiana-based company called Gardes Energy Services Inc. may be used to develop Canada's Manville coalbed methane (CBM) play. Two Canadian companies have recently agreed to test the patented technology in the Manville play, which has a permeability of only 3 to 4 millidarcies in shallower Manville targets and less than 1 millidarcy in deeper targets. The technology entails the drilling of multiple, radial wells with lateral branches. The 2-string dual injection drilling technique allows non-damaging underbalanced drilling of multiple lateral branches in each seam when combined with the patented Upstock process. The Upstock is then lowered to the lowest seam on a carrier string to redirect the drilling assembly into the first coal seam. Drilling fluid is pumped down the drillstring, activating the drilling assembly's mud motor and guidance system. Injection rates are adjusted according to downhole measurement-while drilling pressure sensors to maintain underbalanced drilling. Continuous circulation through the concentric casing system eliminates the potentially damaging surging that occurs in conventional drilling. By reorienting the bent housing on the drilling motor, branch laterals are added in each coal seam. Once completed, the drilling assembly is pulled, the Upstock is lifted on the carrier string to the next seam of interest, and the process is repeated. The dual annulus process lowers the equivalent circulating density below that of the formation pressure, preventing drilling fluid from invading and damaging the formation. Formation water is typically used as the drilling fluid. Once drilling is completed, an electric submersible pump (ESP) is lowered on tubing to the sump area and water is pumped to surface, allowing the methane to desorb and be produced through perforations into and up the inner annulus. The technique reduces the environmental impact of drilling, as 1 area can be used to drain an area the equivalent of 16

Santa Fe Accelerator Conference

International Nuclear Information System (INIS)

Anon.

1983-01-01

The 10th USA National Particle Accelerator Conference was hosted this year by the Los Alamos National Laboratory in Santa Fe from 21-23 March. It was a resounding success in emphasizing the ferment of activity in the accelerator field. About 900 people registered and about 500 papers were presented in invited and contributed talks and poster sessions

Early Neogene unroofing of the Sierra Nevada de Santa Marta along the Bucaramanga -Santa Marta Fault

Science.gov (United States)

Piraquive Bermúdez, Alejandro; Pinzón, Edna; Bernet, Matthias; Kammer, Andreas; Von Quadt, Albrecht; Sarmiento, Gustavo

2016-04-01

Plate interaction between Caribbean and Nazca plates with Southamerica gave rise to an intricate pattern of tectonic blocks in the Northandean realm. Among these microblocks the Sierra Nevada de Santa Marta (SNSM) represents a fault-bounded triangular massif composed of a representative crustal section of the Northandean margin, in which a Precambrian to Late Paleozoic metamorphic belt is overlain by a Triassic to Jurassic magmatic arc and collateral volcanic suites. Its western border fault belongs to the composite Bucaramanga - Santa Marta fault with a combined left lateral-normal displacement. SE of Santa Marta it exposes remnants of an Oligocene marginal basin, which attests to a first Cenoizoic activation of this crustal-scale lineament. The basin fill consists of a sequence of coarse-grained cobble-pebble conglomerates > 1000 m thick that unconformably overlay the Triassic-Jurassic magmatic arc. Its lower sequence is composed of interbedded siltstones; topwards the sequence becomes dominated by coarser fractions. These sedimentary sequences yields valuable information about exhumation and coeval sedimentation processes that affected the massif's western border since the Upper Eocene. In order to analyse uplifting processes associated with tectonics during early Neogene we performed detrital zircon U-Pb geochronology, detrital thermochronology of zircon and apatites coupled with the description of a stratigraphic section and its facies composition. We compared samples from the Aracataca basin with analog sequences found at an equivalent basin at the Oca Fault at the northern margin of the SNSM. Our results show that sediments of both basins were sourced from Precambrian gneisses, along with Mesozoic acid to intermediate plutons; sedimentation started in the Upper Eocene-Oligocene according to palynomorphs, subsequently in the Upper Oligocene a completion of Jurassic to Cretaceous sources was followed by an increase of Precambrian input that became the dominant

Association of 5-HT2C (rs3813929) and UCP3 (rs1800849) gene polymorphisms with type 2 diabetes in obese women candidates for bariatric surgery.

Science.gov (United States)

Schnor, Noa Pereira Prada; Verlengia, Rozangela; Novais, Patrícia Fátima Sousa; Crisp, Alex Harley; Leite, Celso Vieira de Souza; Rasera-Junior, Irineu; Oliveira, Maria Rita Marques de

2017-01-01

Obesity can cause systemic arterial hypertension (SAH) and type 2 diabetes mellitus (DM2) factor that is also influenced by genetic variability. The present study aims to investigate the association between gene polymorphisms related with obesity on the prevalence of SAH and DM2 in the preoperative period and 1 year after Roux-en-Y gastric bypass surgery. In total, 351 obese women in a Brazilian cohort completed the study. The clinical diagnosis of SAH and DM2 was monitored from medical records. Twelve gene polymorphisms (rs26802; rs572169; rs7799039; rs1137101; rs3813929; rs659366; rs660339; rs1800849; rs7498665; rs35874116; rs9701796; and rs9939609) were determined using real-time polymerase chain reaction and TaqMan assay. In the preoperative period, prevalence of SAH and DM2 was 57% and 22%, respectively. One year postoperatively, 86.8% subjects had remission of DM2 and 99.5% had control of SAH. Subjects with T allele from the serotonin receptor gene (5-HT2C, rs3813929) had five times greater chance of DM2, and the CC genotype from uncoupling protein 3 gene (UCP3, rs1800849) had three times greater chance in the preoperative period. These findings indicate that polymorphisms rs3813929 and rs1800849 from 5-HT2C and UCP3 genes were related to DM2 prevalence among the Brazilian obese women candidates for bariatric surgery.

Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes

DEFF Research Database (Denmark)

Hansen, Tue Haldor; Vestergaard, Henrik; Jørgensen, Torben

2015-01-01

,641 glucose tolerant controls, respectively. Quantitative trait analyses were performed in up to 13,605 individuals subjected to an OGTT or blood samples obtained after an overnight fast, as well as in 596 individuals subjected to an IVGTT. Results: Analyses of fasting and OGTT-derived quantitative traits did.......024; P=0.01) assuming a dominant model of inheritance, but failed to replicate a previously reported association with area under the curve (AUC) for insulin. Case control analysis did not show an association of the PTBP1 rs11085226 variant with type 2 diabetes. Conclusions: Despite failure to replicate......Background: The variant rs11085226 (G) within the gene encoding polypyrimidine tract binding protein 1 (PTBP1) was reported to associate with reduced insulin release determined by an oral glucose tolerance test (OGTT) as well as an intravenous glucose tolerance test (IVGTT). The aim of the present...

Clock and trigger distribution for CBM-TOF quality evaluation of RPC super module detector assemblies

Science.gov (United States)

Li, C.; Huang, X.; Cao, P.; Wang, J.; An, Q.

2018-03-01

RPC Super module (SM) detector assemblies are used for charged hadron identification in the Time-of-Flight (TOF) spectrometer at the Compressed Baryonic Matter (CBM) experiment. Each SM contains several multi-gap Resistive Plate Chambers (MRPCs) and provides up to 320 electronic channels in total for high-precision time measurements. Time resolution of the Time-to-Digital Converter (TDC) is required to be better than 20 ps. During mass production, the quality of each SM needs to be evaluated. In order to meet the requirements, the system clock signal as well as the trigger signal should be distributed precisely and synchronously to all electronics modules within the evaluation readout system. In this paper, a hierarchical clock and trigger distribution method is proposed for the quality evaluation of CBM-TOF SM detectors. In a first stage, the master clock and trigger module (CTM) allocated in a 6U PXI chassis distributes the clock and trigger signals to the slave CTM in the same chassis. In a second stage, the slave CTM transmits the clock and trigger signals to the TDC readout module (TRM) through one optical link. In a third stage, the TRM distributes the clock and trigger signals synchronously to 10 individual TDC boards. Laboratory test results show that the clock jitter at the third stage is less than 4 ps (RMS) and the trigger transmission latency from the master CTM to the TDC is about 272 ns with 11 ps (RMS) jitter. The overall performance complies well with the required specifications.

Genetic polymorphisms of IL-18 rs1946518 and IL-1β rs16944 are associated with prognosis and survival of acute myeloid leukemia.

Science.gov (United States)

Wang, Hong; Hua, Mingqiang; Wang, Shukang; Yu, Jie; Chen, Chen; Zhao, Xueyun; Zhang, Chen; Zhong, Chaoqin; Wang, Ruiqing; He, Na; Hou, Ming; Ma, Daoxin

2017-03-01

Though the pathogenesis of AML is still unknown, accumulating evidence revealed that immune response plays a vital part in it. NLRP3 inflammasome as a component of immune system has been found related to several cancers. The single nucleotide polymorphisms (SNPs) of NLRP3 inflammasome genes may be related to pathogenesis and prognosis of AML. We determined polymorphisms of NLRP3 (rs35829419), CARD8 (rs2043211), IL-1β (rs16944), IL-18 (rs1946518) and NF-κB -94 ins/del ATTG in de novo AML patients to find out whether they play roles in the susceptibility and severity of AML. In our study, 383 AML cases and 300 randomly selected healthy individuals were examined for the polymorphisms and expression of NLRP3 genes. IL-1β (rs16944) polymorphism in different risk AML subgroups was found statistically different, with more GA genotype in favorable-risk cytogenetics group. We also demonstrated that the bone marrow blasts of patients carrying IL-18 (rs1946518) GG or GT genotype were higher than patients of TT genotype. IL-18 plasma level of patients with IL-18 (rs1946518) GT or TT genotype was higher than GG genotype. Moreover, the GT genotype of IL-18 (rs1946518) led to statistically poorer AML-specific survival. IL-1β (rs16944) and IL-18 (rs1946518) may be served as potential predictors for AML.

Data integration from gamma radiation decay from uranium: a case-study in the region of Santa Maria, Rio Grande do Sul-Brazil;Integracao de dados de decaimento radiometrico de uranio: estudo de caso na regiao de Santa Maria (RS)

Energy Technology Data Exchange (ETDEWEB)

Pereira, Joao Eduardo; Silva, Jose Luiz Silverio da; Pires, Carlos Alberto, E-mail: jesp61@gmail.co, E-mail: silverio@smail.ufsm.b, E-mail: calpires@base.ufsm.b [Universidade Federal de Santa Maria (CCNE/UFSM), RS (Brazil). Centro de Ciencias Naturais e Exatas. Dept. de Geociencias; Strieder, Adelir Jose, E-mail: adelir@ufrgs.b [Universidade Federal do Rio Grande do Sul (DEM/UFRGS), Porto Alegre, RS (Brazil). Dept. de Engenharia de Minas

2008-09-15

This work consists of data integration of uranium concentrations, parts per million (ppm), associated to the different rock formations belonging to Parana Basin in the region of Santa Maria, in the Rio Grande do Sul state southern Brazil. This study was developed from primary data generated by the Companhia de Pesquisas de Recursos Minerais as part of the AERO/Camaqua; Project, 1010 code series, digitalized in the 1997 Geosoft XYZ format. Through an irregular net of values of uranium concentration, with 25806 observations were spatially oriented by Universal Transverse Mercator/ UTM coordinates. Which were varied from west to east 206190 to 276813 E, and from north to south 6670888 to 6735665 N, totalizing an area of 4574.75 km{sup 2}. Using Statistica 7.1 software licensed to the Department of Statistics at the Federal University of Santa Maria, the mean values of and the confidence limits with alpha = 0.05, the standard deviations of uranium concentrations for each rock formation. The comparisons between the mean values were made through the Tuckey's Test and the spatial variation of the concentrations in relation to the geographical coordinates were adjusted to a polynomial model. The results obtained showed that the uranium concentrations occur in a distinct way in the different geological formations studied (aluvionar unconsolidated sediments, sandstones and igneous volcanic acid and basic rocks). The uranium variable, when spatialized in relation to the geographical coordinates UTM were adjusted to a second order polynomial model. (author)

Streamflow in the upper Santa Cruz River basin, Santa Cruz and Pima Counties, Arizona

Science.gov (United States)

Condes de la Torre, Alberto

1970-01-01

Streamflow records obtained in the upper Santa Cruz River basin of southern Arizona, United States, and northern Sonora, Mexico, have been analyzed to aid in the appraisal of the surface-water resources of the area. Records are available for 15 sites, and the length of record ranges from 60 years for the gaging station on the Santa .Cruz River at Tucson to 6 years for Pantano Wash near Vail. The analysis provides information on flow duration, low-flow frequency magnitude, flood-volume frequency and magnitude, and storage requirements to maintain selected draft rates. Flood-peak information collected from the gaging stations has been projected on a regional basis from which estimates of flood magnitude and frequency may be made for any site in the basin. Most streams in the 3,503-square-mile basin are ephemeral. Ground water sustains low flows only at Santa Cruz River near Nogales, Sonoita Creek near Patagonia, and Pantano Wash near Vail. Elsewhere, flow occurs only in direct response to precipitation. The median number of days per year in which there is no flow ranges from 4 at Sonoita Creek near Patagonia to 335 at Rillito Creek near Tomson. The streamflow is extremely variable from year to year, and annual flows have a coefficient of variation close to or exceeding unity at most stations. Although the amount of flow in the basin is small most of the time, the area is subject to floods. Most floods result from high-intensity precipitation caused by thunderstorms during the period ,July to September. Occasionally, when snowfall at the lower altitudes is followed by rain, winter floods produce large volumes of flow.

APOC3 rs2070666 Is Associated with the Hepatic Steatosis Independently of PNPLA3 rs738409 in Chinese Han Patients with Nonalcoholic Fatty Liver Diseases.

Science.gov (United States)

Zhang, Rui-Nan; Zheng, Rui-Dan; Mi, Yu-Qiang; Zhou, Da; Shen, Feng; Chen, Guang-Yu; Zhu, Chan-Yan; Pan, Qin; Fan, Jian-Gao

2016-08-01

The association between nonalcoholic fatty liver disease (NAFLD) and apolipoprotein C3 gene (APOC3) promoter region single-nucleotide polymorphisms (SNPs) rs2854117 and rs2854116 is controversial. The aim of this study was to investigate the relationship between other polymorphisms of APOC3 and NAFLD in Chinese. Fifty-nine liver biopsy-proven NAFLD patients and 72 healthy control subjects were recruited to a cohort representing Chinese Han population. The polymorphisms in the exons and flanking regions of APOC3 and patatin-like phospholipase domain-containing protein 3 (PNPLA3) rs738409 polymorphisms were genotyped. Among the five SNPs (rs4225, rs4520, rs5128, rs2070666, and rs2070667) in APOC3, only rs2070666 (c.179 + 62 T/A) was significantly different in genotype and allele frequency (both p steatosis (OR 4.986, 95 % CI 1.020-24.371), but neither to liver stiffness measurement values nor to hepatic histological activity and fibrosis in NAFLD patients. The APOC3 rs2070666 A allele is a risk factor for NAFLD independent of obesity, dyslipidemia, and PNPLA3 rs738409, and it might contribute to increased liver fat content in Chinese Han population.

Association of PTPN22 rs2476601 and STAT4 rs7574865 polymorphisms with rheumatoid arthritis: A meta-analysis update.

Science.gov (United States)

Elshazli, Rami; Settin, Ahmad

2015-08-01

Rheumatoid arthritis (RA) is a common autoimmune disease with a complex genetic background. The genes encoding protein tyrosine phosphatase non-receptor type 22 (PTPN22) and signal transducer and activator of transcription 4 (STAT4) have been reported to be associated with RA in several ethnic populations. This work aims to assess the association between PTPN22 rs2476601 and STAT4 rs7574865 polymorphisms with RA susceptibility through an updated meta-analysis of available case-control studies. A literature search of all relevant studies published from January 2007 up to December 2014 was conducted using Pubmed and Science Direct databases. The observed studies that were related to an association between PTPN22 rs2476601 and STAT4 rs7574865 polymorphisms with RA susceptibility were identified. Meta-analysis of the pooled and stratified data was done and assessed using varied genetic models. Thirty-seven case-control studies with a total of 47 comparisons (29 for PTPN22 rs2476601 polymorphism and 18 for STAT4 rs7574865 polymorphism) met our inclusion criteria. The meta-analysis showed an association between PTPN22 T allele, CT+TT and TT genotypes with RA susceptibility. Furthermore, The meta-analysis showed an association between STAT4 T allele, GT+TT and TT genotypes with RA susceptibility. Stratification of RA patients according to ethnic groups showed that PTPN22 T allele, CT+TT genotypes, STAT4 T allele and STAT4 GT+TT were significantly associated with RA in European, Asian, African subjects, while PTPN22 TT genotype was significantly associated with RA in European but not in Asian and African subjects and STAT4 TT genotype was significantly associated with RA in European and Asian but not in African subject. A subgroup analysis according to the presence or absence of rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP) antibodies revealed that the association between PTPN22 rs2476601 and STAT4 rs7574865 polymorphisms with RA susceptibility

78 FR 47007 - National Environmental Policy Act; Santa Susana Field Laboratory

Science.gov (United States)

2013-08-02

... project Web site address listed below. http://www.nasa.gov/agency/nepa/news/SSFL.html . ADDRESSES...; Santa Susana Field Laboratory AGENCY: National Aeronautics and Space Administration (NASA). ACTION... Environmental Cleanup Activities for the NASA-administered portion of the Santa Susana Field Laboratory (SSFL...

Fast reconstruction of trajectories of charged muons recorded by the MUCH detector in the CBM experiment

International Nuclear Information System (INIS)

Ablyazimov, T.O.; Ivanov, V.V.

2017-01-01

The CBM experiment is currently being developed in GSI (Darmstadt, Germany) at the FAIR accelerator complex by an international collaboration including JINR. One of the main goals of the experiment is a research of charmonium production process in nucleus-nucleus collisions at high energies. The registration of such decays as J/ψ → μ"+μ"− is planned to be carried out in real time. The current paper presents an algorithm suitable for fast reconstruction of trajectories of charged muons from J/ψ decays recorded by the MUCH detector. [ru

Developing and Validating a Santa Ana Wildfire Threat Index

Science.gov (United States)

Capps, S. B.; Rolinski, T.; DAgostino, B.; Vanderburg, S.; Fovell, R. G.; Cao, Y.

2014-12-01

Santa Ana winds, common to southern California during the fall through spring, are a type of katabatic wind that originates from a direction generally ranging from 360°/0° to 100° and is usually accompanied by very low humidity. Since fuel conditions tend to be driest from late September through the middle of November, Santa Ana winds occurring during this period have the greatest potential to produce large, devastating fires when an ignition occurs. Such catastrophic fires occurred in 1993, 2003, 2007, and 2008. Because of the destructive nature of these fires, there has been a growing desire to categorize Santa Ana wind events in much the same way that tropical cyclones have been categorized. The Santa Ana Wildfire Threat index (SAWT) is an attempt to categorize such events with respect to fire activity, based on surface wind velocity, dew point depression, and forecasted fuel conditions. The index, a USDA Forest Service product, was developed by the Forest Service in collaboration with San Diego Gas and Electric Utility (SDG&E), the Department of Atmospheric and Oceanic Sciences at UCLA, The Desert Research Institute (DRI), and Vertum Partners. The methodology behind the SAWT index, along with the index itself will be presented in detail. Also, there will be a discussion on the construction of a 30-year climatology of the index, which includes various meteorological and fuel parameters. We will demonstrate the usefulness of the index as another decision support tool for fire agencies and first responders, and how it could assist the general public and private industry in the preparation of critical Santa Ana wind events.

Polymorphisms of transforming growth factor beta 1 (RS#1800468 and RS#1800471) and esophageal squamous cell carcinoma among Zhuangese population, China.

Science.gov (United States)

Tang, Ren-Guang; Huang, Yong-Zhi; Yao, Li-Min; Xiao, Jian; Lu, Chuan; Yu, Qian

2013-01-01

Epidemiological evidence has shown two polymorphisms (namely RS#1800468G>A and RS#1800471G>C) of transforming growth factor-beta 1 (TGF-β1) gene may be involved in the cancer development. However, their role in the carcinogenic process of esophageal squamous cell carcinoma (ESCC) has been less well elaborated. We conducted a hospital-based case-control study including 391 ESCC cases and 508 controls without any evidence of tumors to evaluate the association between these two polymorphisms and ESCC risk and prognosis for Zhuangese population by means of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and amplification refractory mutation system (ARMS)-PCR techniques. We found that individuals with the genotypes with RS#1800471 C allele (namely RS#1800471-GC or -CC) had an increased risk of ESCC than those without above genotypes (namely RS#1800471-GG, adjusted odds ratio 3.26 and 5.65, respectively). Further stratification analysis showed that this polymorphism was correlated with tumor histological grades and TNM (tumor, node, and metastasis) stage, and modified the serum levels of TGF-β1. Additionally, RS#1800471 polymorphism affected ESCC prognosis (hazard ratio, 3.40), especially under high serum levels of TGF-β1 conditions. However, RS#1800468 polymorphism was not significantly related to ESCC risk. These findings indicated that TGF-β1 RS#1800471G>C polymorphism may be a genetic modifier for developing ESCC in Zhuangese population. Copyright © 2012 Elsevier B.V. All rights reserved.

Hubungan Kadar Gula Darah saat Masuk Rumah Sakit dengan Jenis Sindroma Koroner Akut di RS Dr. M. Djamil Padang

Directory of Open Access Journals (Sweden)

Willy Valerian

2015-05-01

Full Text Available AbstrakSindrom Koroner Akut (SKA merupakan spektrum dari penyakit arteri koroner yang tidak stabil, mulai dari angina pektoris tidak stabil sampai infark miokardium. SKA terbagi atas Unstable Angina Pectoris (UAP, ST elevation myocardial infarction (STEMI, Non-ST elevation myocardial infarction (NSTEMI. Tujuan penelitian ini adalah untuk menentukan hubungan antara kadar gula darah saat masuk rumah sakit dan jenis SKA. Metode penelitian yang digunakan adalah cross sectional. Penelitian dilakukan di Instalasi Rekam Medik RS Dr. M. Djamil Padang dengan mengambil data pasien SKA dari Januari 2012 sampai Desember 2012. Hasil penelitian ini didapatkan jenis SKA dengan gula darah yang tidak normal dari 60 sampel, yaitu: UAP 25%, NSTEMI 35%, STEMI 40%. Hasil pengolahan data dapat dilihat bahwa nilai p = 0,592 yang artinya tidak terdapat hubungan yang bermakna antara kadar gula darah saat masuk rumah sakit dengan jenis SKA. Hal ini terjadi mungkin karena terlalu sedikitnya sampel dan banyak sampel kriteria ekslusi dalam pencarian data. Sebaiknya dalam penelitian yang akan datang dapat memperbanyak sampel.Kata kunci: sindrom koroner akut, kadar gula darah, hubungan kadar gula darah dengan SKA AbstractAcute Coronary Syndrome (ACS is a spectrum of coronary artery disease that is not stable, ranging from unstable angina to myocardial infarction. Acute Coronary Syndrome is divided into Unstable Angina Pectoris (UAP, ST elevation myocardial infarction (STEMI, non-ST elevation myocardial infarction (NSTEMI. The objective of this study was to determine the relationship between blood sugar levels when admitted to hospital and Acute Coronary Syndrome type by using cross sectional study. The study was conducted at the Medical Records RS Dr. M. Djamil Padang. The ACS data collected from January 2012 until December 2012. The results of this study was found the SKA with abnormal blood sugar of 60 samples, i.e. UAP25%, NSTEMI35%, 40% STEMI. On the results of data

75 FR 81846 - Expansion of the Santa Maria Valley Viticultural Area

Science.gov (United States)

2010-12-29

... decision. SUMMARY: This Treasury decision expands the Santa Maria Valley viticultural area in Santa Barbara... may purchase. DATES: Effective Date: January 28, 2011. FOR FURTHER INFORMATION CONTACT: Elisabeth C... origin of their wines to consumers and helps consumers to identify wines they may purchase. Establishment...

78 FR 55763 - National Environmental Policy Act; Santa Susana Field Laboratory

Science.gov (United States)

2013-09-11

... document format at http://www.nasa.gov/agency/nepa/news/SSFL.html . The Federal Register Notice of Intent...; Santa Susana Field Laboratory AGENCY: National Aeronautics and Space Administration (NASA). ACTION... Demolition and Environmental Cleanup Activities for the NASA-administered portion of the Santa Susana Field...

Adiponectin gene polymorphism rs2241766 T/G is associated with response to pioglitazone treatment in type 2 diabetic patients from southern China.

Directory of Open Access Journals (Sweden)

Hong Yang

Full Text Available INTRODUCTION: Insulin sensitizing drugs such as pioglitazone are not uniformly treatment effective among individual type 2 diabetic patients. Here, the relationship of pioglitazone efficacy to single nucleotide polymorphisms (SNP of the adiponectin gene, a critical gene directly regulated by the drug, was examined in a cohort of Chinese Han type 2 diabetic patients. METHODS: Eighty type 2 diabetic patients were treated with pioglitazone (15 mg/day for 12 weeks without interruption of their current therapeutic regimen. Fasting plasma glucose, fasting insulin, homeostasis model assessment for insulin resistance (HOMA-IR, and glycated hemoglobin (HbA1c% were collected both prior to and following pioglitazone treatment. Response to pioglitazone was defined as a decrease of at least 15% in HbA1c% levels. Three regions of the adiponectin gene containing SNPs (promoter, intron 2 and exon 2, and exon 3 were amplified and sequenced to determine genotype. RESULTS: Serum adiponectin levels were significantly increased (p<0.001 whereas fasting plasma glucose, fasting insulin, HOMA-IR, and HbA1c% values were significantly decreased relative to baseline measurements (p<0.001. Response of patients with TG and TT genotypes at rs2241766 (exon2; 52.9% vs. 12.7%, respectively p = 0.001 was statistically significant relative to all other patients. Amongst rs2241766 TG and TT patients, the mean decrease in HbA1c% levels was greater where the genotype was TG (1.15±0.80 vs. 0.52±0.64, p = 0.001. CONCLUSIONS: The adiponectin gene polymorphism rs2241766 T/G is associated with pioglitazone efficacy in type 2 diabetic patients, and status of the polymorphism may be an important clinical factor to consider prior to pioglitazone treatment.

Genetic polymorphisms of surfactant protein D rs2243639, Interleukin (IL)-1β rs16944 and IL-1RN rs2234663 in chronic obstructive pulmonary disease, healthy smokers, and non-smokers.

Science.gov (United States)

Issac, Marianne Samir M; Ashur, Wafaa; Mousa, Heba

2014-06-01

Chronic obstructive pulmonary disease (COPD) is a complex chronic inflammatory disease that involves the activity of various inflammatory cells and mediators. It has been suggested that susceptibility to COPD is, at least in part, genetically determined. The primary aim of this study was to investigate the association between surfactant protein D (SFTPD) rs2243639, interleukin (IL)-1β rs16944 and IL-1 receptor antagonist (IL-1RN) rs2234663 gene polymorphisms and COPD susceptibility, as well as examining the association between the various IL-1RN/IL-1β haplotypes and pulmonary function tests (PFT). Secondly, we aimed to examine the influence of SFTPD rs2243639 polymorphism on serum surfactant protein D (SP-D) level. A total of 114 subjects were recruited in this study and divided into three groups: 63 COPD patients, 25 asymptomatic smokers, and 26 healthy controls. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was performed for the detection of SFTPD rs2243639 and IL-1β rs16944 polymorphisms. Detection of variable numbers of an 86-bp tandem repeat (VNTR) of IL-1RN was done using PCR. Serum SP-D level was measured using enzyme linked-immunosorbent assay. PFTs were measured by spirometry. Carriers of the SFTPD AG and AA polymorphic genotypes constituted 71.4 % of COPD patients versus 48 % in asymptomatic smokers, with a statistically significant difference between the two groups (p = 0.049). Smokers who were carriers of the polymorphic SFTPD rs2243639 A allele (AG and AA genotypes) have a 2.708 times risk of developing COPD when compared with wild-type GG genotype carriers [odds ratio (OR) 2.708 (95 % CI 1.041-7.047)]. Forced expiratory flow (FEF) 25-75 % predicted was higher in IL-1RN*1/*1 when compared with *1/*2 (p = 0.013). FEF25-75 % predicted in carriers of haplotype IL-1RN *1/IL-1β T (49.21 ± 10.26) was statistically significantly higher than in carriers of IL-1RN *2/IL-1β T (39.67 ± 12.64) [p = 0

Central hydroelectric of Santa Ana

International Nuclear Information System (INIS)

Pardo A, German

2000-01-01

The paper is related to the construction of an alternating tunnel of conduction to take advantage of the available hydraulic load among the Wiesner Plant and Santa Ana's tanks and of Suba, works required to build a hydroelectric power station with a generation capacity of approximately of 12 MW

Quality of Schizolobium parahyba seeds and seedlings from Rio Grande do Sul, Santa Catarina and Paraná states

Directory of Open Access Journals (Sweden)

Edicléia Aparecida Iensen Cherobini

2010-09-01

Full Text Available This research aimed to study the vigor and the quality of Schizolobium parahyba seeds from samples of three differentstates, Rio Grande do Sul (RS, Santa Catarina (SC and Paraná (PR and to evaluate the seedlings quality produced by these seeds.The seeds were submitted to evaluations of moisture content, germination, vigor and healthy. The seedlings quality was evaluated byhard seeds, dead seeds, emergence, seedling height, root length, collar diameter, fresh and dry weight of seedlings. On the seedsevaluations, the samples from SC and PR presented better results for first count of germination, dry matter and accelerate aging. Thefungi associated to the seeds were Aspergillus sp., Alternaria sp., Penicillium sp. and Trichoderma sp. About the seedlings evaluations,seeds from PR showed the bests results when the differences between tests were significant (emergence, root length and dry weight ofseedlings. Some of the labs variables had correlation with the seedlings variables.

CITY OF SANTA FE V. KOMIS REVISITED: AN ANALYSIS OF THE ACTUAL IMPACTS OF CONSTRUCTION AND OPERATION OF THE SANTA FE BYPASS ON THE VALUE OF NEARBY REAL ESTATE

International Nuclear Information System (INIS)

Bentz, E. J. Jr.; Bentz, C. B.; O'Hora, T. D.; Baepler, D.

2003-01-01

The Santa Fe Bypass for transport of transuranic waste (TRU) to the Waste Isolation Pilot Plant (WIPP) near Carlsbad, New Mexico has been constructed and is operational (as of 2000). This paper presents a review of actual empirical data from the sales of real estate in the Santa Fe City/County area since the filing of the City of Santa Fe v. Komis lawsuit in 1988. The data analyzed covers the time period from 1989 through the last quarter of 2001

Genetic polymorphism rs3760396 of the chemokine (C-C motif) ligand 2 gene (CCL2) associated with the susceptibility of lung cancer in a pathological subtype-specific manner in Han-ancestry Chinese: a case control study

International Nuclear Information System (INIS)

Li, Xu; Lin, Fangcai; Zhou, Hong

2016-01-01

Chemokines are well known inflammatory factors critical for tumor development in diverse tissues, including lung cancer. Chemokine (C-C motif) Ligand 2 (CCL2) was one of such chemokines important for both primary tumor development and metastasis of various cancers. Polymorphism at rs3760396 of CCL2 genes is associated with the prognosis of non-small cell lung cancer (NSCLC). The goal of our study was to examine the relationship of genetic polymorphisms rs3760396 with the susceptibility of lung cancer and its pathological subtypes in Han-ancestry Chinese population. rs3760396 G/C polymorphism of CCL2 was genotyped using PCR in 394 patients with lung cancer and 545 cancer-free controls from the same Northeast region of China. After controlling for gender, age and smoking status, no significant association was observed between rs3760396 polymorphism and overall lung cancer. However, minor allele G of rs3760396 polymorphism was significantly associated with increased risk of adenosquamous lung carcinoma with either allelic genetic model (OR = 5.29, P < 0.001), or dominant genetic model (OR = 9.88, P < 0.001), or genotypic model (GC genotype vs. CC genotype, OR = 10.73, P < 0.001). Although rs3760396 polymorphism was not significantly associated with increased risk of adenocarcinoma subtype, it was nominally associated with the pooled outcome of either adenocarcinoma or adenosquamous carcinoma under allelic genetic model (OR = 1.54, P = 0.023) or dominant genetic model (OR = 1.57, P = 0.031). Our study suggested rs3760396 polymorphism of CCL2 is associated not only with prognosis of NSCLC, but also with risk of lung cancer in a subtype-specific manner. Our results further supported previous evidence of the important role of CCL2 in lung cancer development

Prototyping the read-out chain of the CBM Microvertex Detector

International Nuclear Information System (INIS)

Klaus, P.; Wiebusch, M.; Amar-Youcef, S.; Deveaux, M.; Koziel, M.; Michel, J.; Milanovic, B.; Müntz, C.; Tischler, T.; Stroth, J.

2016-01-01

The Compressed Baryonic Matter (CBM) Experiment at the future FAIR (Darmstadt/Germany) will study the phase diagram of hadronic matter in the regime of highest net-baryon densities. The fixed target experiment will explore the nuclear fireballs created in violent heavy ion reactions with a rich number of probes. To reconstruct the decay topologies of open-charm particles as well as to track low-momentum particles, an ultra-light and precise Microvertex Detector (MVD) is required. The necessary performance in terms of spatial resolution, material budget and rate capability will be reached by equipping the MVD with highly granular, radiation-hard CMOS Monolithic Active Pixel Sensors (CPS) developped at IPHC Strasbourg, which are operated in the target vacuum of the experiment. This contribution introduces the concept of the MVD and puts a focus on the latest results obtained from the R and D of the electronics and read-out chain of the device. Moreover, we briefly introduce the PRESTO project, which realises a prototype of a full size quadrant of an MVD detector station

Association of the matrix metalloproteinase-3 polymorphisms rs679620 and rs3025058 with ischemic stroke risk: a meta-analysis

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Zhang Q

2018-01-01

Full Text Available Qi-Wei Zhang Department of Neurosurgery, The Affiliated Hospital of Jilin Medical University, Jilin, People’s Republic of China Purpose: The relationship of the matrix metalloproteinase-3 (MMP-3 polymorphisms rs679620 and rs3025058 with ischemic stroke has received much attention. The aim of the present study was to perform a meta-analysis of published case–control studies to evaluate the cumulative evidence.Methods: We performed a search of ISI Web of Science, Embase, PubMed, and China National Knowledge Infrastructure databases. Pooled odds ratios (ORs were appropriately derived from fixed-effects or random-effects models.Results: We identified seven eligible studies including 5,204 subjects. The pooled analysis showed that the MMP-3 rs679620 A allele carriers had increased risk of ischemic stroke compared with homozygotes for the G allele in Asians (AA + GA vs GG: OR =1.42, 95% CI: 1.05–1.91, P=0.022. Concerning the rs3025058 polymorphism, the results did not suggest an association between rs3025058 genotypes and ischemic stroke risk (5A5A + 6A5A vs 6A6A: OR =1.04, 95% CI: 0.73–1.47, P=0.844; 5A5A vs 6A5A + 6A6A: OR =1.14, 95% CI: 0.74–1.77, P=0.556; and 5A5A vs 6A6A: OR =1.11, 95% CI: 0.68–1.80, P=0.677. In subgroup analysis by ethnicity, no statistically significant associations were demonstrated for rs3025058 in Asians and Caucasians, respectively. There was no evidence for publication bias.Conclusion: Our findings indicate that the rs679620 A allele carriers have increased risk of ischemic stroke in Asians, but there is no association between rs3025058 and ischemic stroke risk. Keywords: ischemic stroke, meta-analysis, MMP-3, polymorphism

Zoneamento ambiental dos banhados da Estação Ecológica do Taim, RS Environmental zoning of swamps in the Ecological Station of Taim, RS, Brazil

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Fabio Charão Kurtz

2003-02-01

Full Text Available O "Zoneamento Ambiental dos Banhados da Estação Ecológica do Taim" permitiu avaliar a deterioração ambiental dos ecossistemas existentes na Estação Ecológica do Taim (ESEC/TAIM, municípios de Rio Grande e Santa Vitória do Palmar (RS. Consideraram-se dois tipos distintos de ecossistemas: o do Banhado (ECO1 = Ecossistema Límnico e o da Planície Marítima (ECO2 = Ecossistema Planície Marítima. A ECO TOTAL (ECO1 + ECO2 apresentou 64% de classe APP (Área de Preservação Permanente, 27,6% de ACP (Área de Conservação Permanente, 5,6% de AUO (Uso e Ocupação; em menor porcentagem encontrou-se a classe AR (Área de Restauração com 2,8%. A deterioração ambiental média para o ECO1 foi de 10,32%, sendo menor que a ECO2 (23,94%. A deterioração ambiental da ESEC/TAIM (ECO ficou em 13,65%. Com relação à análise de regressão para ECO1, concluiu-se que com 06 parâmetros ambientais se obteve a precisão de 95%, enquanto que, com 04 parâmetros ambientais obteve-se a mesma precisão para a ECO2. Com relação à análise fatorial concluiu-se que essa técnica permitiu conhecer a estrutura dos dados, mostrando as correlações entre cada variável (classes de exuberância e seu respectivo fator, entretanto não foi possível separar grupos ou quantificar a influência de uma ou mais variáveis sobre outra de interesse (variável resposta, como por exemplo: quantos parâmetros são necessários para elaborar um zoneamento ambiental, sendo esta pergunta respondida pela análise de regressão. Recomenda-se que o zoneamento ambiental seja elaborado pelos órgãos públicos ambientais nas demais estações ecológicas e nas unidades de conservação.The "Environmental Zoning of swamps in the Ecological Station of Taim (RS" allowed to evaluate an environmental deterioration of the existent ecosystems in the Ecological Station of Taim (ESEC/TAIM; municipal districts of Rio Grande and Santa Vitória do Palmar (RS. Two types of different

Impact of TNF-α (rs1800629 and IL-6 (rs1800795 Polymorphisms on Cognitive Impairment in Asian Breast Cancer Patients.

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Jung-Woo Chae

Full Text Available Expression of pro-inflammatory cytokines is influenced by single nucleotide polymorphisms (SNPs in the promoter regions of the pro-inflammatory cytokine genes, and cytokines are associated with the occurrence of post-chemotherapy cognitive impairment. Hence, the aim of this study was to evaluate the associations between two common pro-inflammatory cytokine gene polymorphisms namely, IL6-174 (rs1800795 G>C and TNF-308 (rs1800629 G>A, and chemotherapy-associated cognitive impairment (CACI among Asian early-stage breast cancer patients. In addition, the differential effect of these SNPs on plasma IL-6 and TNF-α levels, and the associations of plasma IL-6 and TNF-α levels with CACI were also assessed.Asian early-stage breast cancer patients (Stage I to III receiving chemotherapy were prospectively recruited from two cancer centers in Singapore. Patients' cognitive function was longitudinally assessed using the validated FACT-Cog (ver. 3 and an objective computerized battery, Headminder™ at three-time points. Plasma IL-6 and TNF-α levels were analyzed using the multiplex immunoassay, and genotyping was performed using Sanger sequencing. Regression analyses and generalized estimating equation were utilized for statistical analysis.A total of 125 patients were included (mean age: 50.3; Chinese: 80.8%; post-menopausal: 48.0%; 68.0% received anthracycline-based chemotherapy. 36.8% patients experienced self-perceived cognitive impairment, detected in memory (32.8% and attention (34.2% domains. Patients with higher levels of anxiety (p<0.001 and insomnia (p = 0.003 also reported more self-perceived cognitive impairment. Higher plasma concentrations of IL-6 were associated with greater severity of self-perceived cognitive impairment (p = 0.001. Polymorphisms of cytokine genes were not associated with expression of plasma cytokines.Present findings further contribute to the growing evidence that supports the role of the pro-inflammatory cytokine IL-6 in

La Ex Hacienda de Santa Cruz

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Berta Pinto de Estrada

1975-06-01

Full Text Available Ex hacienda Santa Cruz was chosen to show the differences in the geographic and economic structure, and the historic causes that originated them, as an example of ihe situation in the northem part of Campeche.

Oral health of the Paleoamericans of Lagoa Santa, Central Brazil.

Science.gov (United States)

Da-Gloria, Pedro; Larsen, Clark Spencer

2014-05-01

The peopling, origins, and early prehistory of the Americas are topics of intense debate. However, few studies have used human remains to document and interpret patterns of health and lifestyle of Paleoamericans. This study provides the first investigation to characterize oral health in a series of early Holocene skeletal remains from Lagoa Santa, Brazil, a locality containing the remains of some of the earliest inhabitants of South America (10,000-7,000 BP). The sample is composed of 949 teeth and 1925 alveoli from an estimated 113 individuals excavated from 17 archaeological sites located in the State of Minas Gerais. We compare dental caries and abscess prevalence at Lagoa Santa to a large sample of human skeletons from the Western Hemisphere Project (WHP) database using both individual and tooth/alveolus count methods. In addition, antemortem tooth loss and tooth wear were analyzed in Lagoa Santa by sex and age. The results show that Lagoa Santa dental caries and abscess prevalence are significantly higher than observed among other hunter-gatherers included in the WHP database, except when abscess prevalence is considered by individual count. Adult females have less tooth wear coupled with higher prevalence of dental caries and antemortem tooth loss than adult males. These results point to an unexpected record of poor oral health at Lagoa Santa, especially among females. A diet based on a highly cariogenic combination of wild tubers and fruits is suggested as an explanation for the elevated rate, characterizing an early adaptation to a tropical environment in South America. Copyright © 2014 Wiley Periodicals, Inc.

Seismic applications in CBM exploration and development

Energy Technology Data Exchange (ETDEWEB)

Richardson, S.E.; Lawton, D.C. [Calgary Univ., AB (Canada)

2002-07-01

This Power Point presentation reviewed seismic methods, coal seam seismology, seismology and coalbed methane (CBM) development, and time-lapse seismic imaging with reference to numerical modelling and physical testing. The issue of resolution versus detection in various seismic methods was discussed. The thinnest resolvable beds are usually about 1.0 m thick. Coal zones with thin seams can be mapped using seismic reflection, but individual seams are difficult to resolve in field data. In terms of coal seismology, it was noted that seismic surveys make it possible to identify seam thickness, field geometry, subsurface structuring and facies changes. Facies model make it possible to determine the depositional environment, coal type, coal quality and lateral continuity. Some successes in coal seismology include the Cedar Hill and Ferron fields in the San Juan Basin. Numerical modelling methods include digital dipole compressional sonic and density well logs through Ardley Coal Zone, P-wave synthetic seismograms generated in SYNTH (MATLAB), and the alteration of density/velocity values to create new seismograms. Another numerical method is to take the difference between original and altered seismograms. It was shown that dewatering causes a decrease in velocity of about 20 per cent, and a 15 per cent decrease in density. Changes as small as 5 per cent in reservoir properties can be successfully imaged. It was concluded that the identification of dewatered zones allow for optimal positioning of development wells. Further physical testing will involve wet and dry p-wave velocities, s-wave velocities will be tested, and velocities will be measured under pressure. 2 tabs., 10 figs.

Communication of work accidents involving biological material: a study in the city of Santa Cruz do Sul/RS

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Dayane Diehl

2012-07-01

Full Text Available Rationale and Objectives: Healthcare workers are constantly exposed to the risk of occupational accidents involving biological material. Thus the aim of the study was to develop a profile of workers involved in workplace accidents with biological materials in Santa Cruz do Sul, through the number of notifications made in information systems. Methods: Transversal retrospective study with a quantitative approach; data collection was carried out between the years 2008 and 2010 from medical records in the Municipal Reference Occupational Health Unit – UMREST – containing the notification via Individual Report of Accident Notification - RINA, and/or Work Accident Communication - CAT. Results: A total of 1,263 records were analyzed during the study period. There were 13 notifications in 2008, 7 cases in 2009 and 2 in 2010. Five records had CAT, 8 had RINA and 9 had RINA and CAT. The most frequently affected professional category was the nursing technician, with the highest frequency in 2008, followed by dentists and nurses. There was a higher prevalence of female workers, with 18 cases. The most prevalent age group was 20 to 49 years old. Conclusion: The study showed that women working in the nursingprofession at the productive-age group are the ones most often affected by work accidents involving biological material during the study period. The study results raise the suspicion of underreporting of accidents with biological material, considering the number of notifications in thesetting of records found in the investigated UMREST. KEYWORDS Wo rk-related accidents. Health care professional. Occupational accidents.

Determination of IL-1B (rs16944) and IL-6 (rs1800796) genetic polymorphisms in IgA nephropathy in a northwest Chinese Han population.

Science.gov (United States)

Zhang, Daofa; Xie, Maowei; Yang, Xiaohong; Zhang, Yin; Su, Yan; Wang, Yanni; Huang, Haiyang; Han, Hui; Li, Wenning; Fu, Keying; Su, Huiluan; Xu, Wentan; Han, Yeguang; Wang, Ru; Zhang, Pei; Wu, Wei; Huang, Yun; Chen, Daojun; Jin, Tianbo; Wei, Jiali

2017-09-22

IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide, but etiology and pathogenesis continue to be poorly understood. Polymorphisms in the cytokine genes may play a role in the etiology and pathogenesis of IgAN. The incidence of different between diverse ethnic groups suggested important genetic influences on its pathogenesis. We genotype 10 single nucleotide polymorphisms (SNPs) in IL-1B and IL-6 gene using Sequenom Mass-ARRAY technology from 417 IgAN patients and 463 healthy controls of the Chinese Han population. We evaluated these SNPs associated with IgAN utilising the chi-square tests and genetic model analysis. We identified that the minor alleles of rs16944 ("A"), rs1800796 ("G") in IL-1B, IL-6 were involved in an increasingly risk of IgAN in allelic model analysis, respectively. The rs16944 in IL-1B and rs1800796 in IL-6 were associated with 1.23-fold (95% CI, 1.02-1.48, P = 0.031) and 1.33-fold (95% CI, 1.11-1.66, P = 0.003) increases in the risk of developing IgAN, respectively. There was only rs1800796 still correlated with IgAN in the allelic model after adjustment by age and gender and the Bonferroni correction. In addition, Haplotype G rs1800796 A rs2069837 G rs2069840 ( P = 0.037) and G rs1800796 A rs2069837 C rs2069840 ( P = 0.042) in IL-6 were considered to be associated with increased IgAN risk. This study verified the IL-6, IL-1B genetic variants polymorphisms contributed to IgAN susceptibility in a Chinese Han population. Although we identified SNPs susceptibility, however, replication studies and functional research are required to confirm the genetic contribution in IgAN.

Caracterização do processo de rigor mortis em músculos de cordeiros da raça Santa Inês e F1 Santa Inês x Dorper Characterization of rigor mortis process of muscles lamb of Santa Inês breed and F1 Santa Inês x Dorper

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Rafael dos Santos Costa

2011-01-01

Full Text Available O desenvolvimento do processo de rigor mortis nas carcaças dos animais de açougue influenciam diretamente a qualidade da carne. As características do processo de rigor mortis em carcaça de ovinos durante o processamento industrial para obtenção de carcaças resfriadas já foram estudadas em outros países e no Brasil em ovinos Santa Inês, mas ainda não estabelecidas em ovinos F1 Santa Inês x Dorper. Assim, objetivou-se neste trabalho caracterizar o processo de rigor mortis dos músculos Semitendinosus e Triceps brachii durante o resfriamento industrial e maciez da carne, em 10 carcaças ovinas. Foram escolhidos aleatoriamente 10 ovinos machos inteiros, sendo seis da raça Santa Inês e quatro F1 Santa Inês x Dorper, abatidos no Matadouro Frigorífico de Campos - Campos dos Goytacazes, Rio de Janeiro. Após a sangria, analisou-se temperatura, pH, comprimento de sarcômero em diferentes intervalos de tempo (4h; 6h; 8h; 10h; 12h; e 24h e força de cisalhamento ou maciez às 48h, do músculo Semitendinosus. Paralelamente, foi realizada a correlação entre a análise sensorial e a análise instrumental desse músculo. A temperatura da câmara fria variou de 12,2°C (4h a -0,5°C (24h e a temperatura média das carcaças foi de 26,80°C e -0,20°C, respectivamente. O pH médio inicial do músculo Semitendinosus foi de 6,62 e o final 5,64 enquanto no músculo T. brachii foi de 6,50 (4h e 5,68 (24h. A contração máxima do sarcômero do músculo Semitendinosus ocorreu na 12ªh(1,50mm após a sangria e no músculo Triceps brachii, no intervalo entre a 10ªh e 24ªh (1,53 a 1,57mm. No músculo Semitendinosus a força de cisalhamento ou maciez foi semelhante entre cordeiros da raça Santa Inês e F1 Santa Inês x Dorper, demonstrando que o grupo genético não influencia na maciez da carne. O painel sensorial confirmou os resultados obtidos na análise instrumental. Na correlação da análise instrumental (força de cisalhamento com a an

Four therapeutic cases of RS3PE syndrome

International Nuclear Information System (INIS)

Nakajima, Naoya; Fukuda, Yukiko; Yang, Kwang-Seok; Aiba, Miyoji; Tsuda, Hiroshi

2007-01-01

RS3PE syndrome (Remitting Seronegative Symmetrical Synovitis with Pitting Edema Syndrome) is one of the disorders which present as polyarthritis. It is important to be aware of RS3PE syndrome when encountering elderly patients with polyarthritis who are negative for rheumatoid factor. We report 4 cases of RS3PE syndrome. All cases shared common clinical findings, such as acute onset, symmetrical polyarthritis, pitting edema of the hands and feet, and being negative for rheumatoid factor in serum. Treatment with corticosteroid was very effective in all cases. However, two patients showed a deteriorated clinical condition during the tapering of corticosteroid. Corticosteroid should be tapered off cautiously in patients with RS3PE syndrome. (author)

[Effect of Electroacupuncture at "Neiguan" (PC 6) and "Tianshu" (ST 25) for Colonic Motility and D 2 Receptor in Irritable Bowel Syndrome Rats].

Science.gov (United States)

Wang, Shan; Guo, Meng-Wei; Gao, Yu-Shan; Ren, Xiao-Xuan; Lan, Ying; Ji, Mao-Xian; Wu, Yan-Ying; Li, Kai-Ge; Tan, Li-Hua; Sui, Ming-He

2018-01-25

To observe and compare the effects of electroacupuncture (EA) at "Tianshu" (ST 25) and "Neiguan" (PC 6) for colonic motility and the expression of colon dopamine D 2 in irritable bowel syndrome (IBS) rats, and to explore the specificity of different meridians and different acupoints. Forty Wistar newborn rats were randomly divided into blank, model, Tianshu and Neiguan groups. Separation of mother and child and acetic acid coloclyster combined with colorectal distension were used to establish IBS model in the model, Tianshu and Neiguan groups. At the age of 9 weeks, EA at bilateral ST 25 and PC 6 were applied in the corresponding groups 5 times, once every other day. After the intervention, the Bristol fecal score, the latent period of abdominal retraction reflex and the number of contraction waves were recorded. The expression of dopamine D 2 receptor was detected by immunohistochemistry. Compared with the blank group, the Bristol fecal score of the model group was higher ( P <0.01), the 1 st contraction wave latent period was shorter ( P <0.01), the number of contraction waves in 90 s increased ( P <0.01), the immunoreactive expression of D 2 receptor in colon decreased ( P <0.01). Compared with the model group, the Bristol fecal scores of the Tianshu and Neiguan groups decreased ( P <0.01), the 1 st contraction wave latent periods were longer ( P <0.01), the numbers of contraction waves in 90 s decreased ( P <0.01), the positive expressions of D 2 receptor in colon increased ( P <0.01, P <0.05). Compared with the Tianshu group, the immunoreactive expression of D 2 receptor in the Neiguan group decreased ( P <0.01). EA at ST 25 and PC 6 can improve the symptoms of colonic motility in IBS rats. The effect of EA at ST 25 is better, which indicates that different meridians and different acupoints play specific effects.

Balance of longwave radiation employing the rate of solar radiation for Santa Maria, Rio Grande do Sul, Brazil1

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Evandro Zanini Righi

Full Text Available New coefficients were determined for the weighting term for cloudiness in the Brunt-Penman equation using the rate of solar radiation (RK in place of the rate of sunshine duration (n/N. The coefficients in the Brutsaert method proposed for daytime in southern Brazil were also tested and adjusted, and the method was selected which gave the more accurate daily results in relation to the original Brunt-Penman equation, for Santa Maria in the state of Rio Grande do Sul, Brazil (RS. Meteorological data covering 2,472 days obtained from the automatic and conventional weather stations in Santa Maria were used. The coefficients were adjusted by linear and nonlinear regression methods depending on the model, using 2/3 of the data. The adjusted equations were tested with the remaining 1/3 of the data. The Brunt-Penman equation modified by the term for cloudiness weighted both for solar radiation incident on the surface with no cloudiness (RK,R and for solar radiation incident at the top of the atmosphere (RK,K, were those that resulted in the best statistical indices relative to the original Brunt-Penman equation. In those equations the boundary conditions, 0.3 ≥ RK,R ≥ 1 or RK,K ≤ 0.22, were imposed. Although having similar statistical indices, a sensitivity analysis showed that the Brutsaert equation and other weightings for cloudiness resulted in larger deviations when compared to the original Brunt-Penman equation, in addition to having greater complexity for practical application.

Anofelinos de Santa Catarina (Diptera: Culicidae, Brasil Anophelines of Santa Catarina (Diptera: Culicidae, Brazil

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Maria da Graça Teixeira Portes

2010-04-01

Full Text Available INTRODUÇÃO: No Brasil, a Região Amazônica é endêmica em malária. Em Santa Catarina, a malária foi eliminada na década de 80. A partir daí, ocorreram poucos casos autóctones isolados, e esporádicos. No entanto, em função da existência do vetor em seu território, da existência de extensa área endêmica no Brasil e da grande mobilidade de pessoas em áreas turísticas no estado, existe a probabilidade de reintrodução da doença. MÉTODOS: Utilizou-se os seguintes dados: Banco de Dados do Núcleo de Entomologia da Fundação Nacional de Saúde, Santa Catarina (ACCES,1997-2000; Sistema de Informação de Vigilância Epidemiológica, Secretaria de Vigilância em Saúde (Malária/SC e Sistema de Informação de Notificação e Agravo(SINAN/SC. Os mesmos foram transportados e analisados, no programa Microsoft Office Excel 2007. RESULTADOS: As coletas foram realizadas em 48 municípios, 159 localidades, sendo identificados 12.310 Culicídeos, 11.546 (93,7% Anopheles e 764 (6,2% como outros. Foram identificados três subgêneros e 13 espécies de anofelinos. CONCLUSÕES: Considerando que nos municípios pesquisados, foi identificada a presença de importantes vetores como Anopheles cruzii e Anopheles albitasis e há circulação de pessoas infectadas provenientes de áreas endêmicas, pode-se considerar que os mesmos são áreas receptivas e vulneráveis à malária. Essas espécies são suspeitas de serem responsáveis pela transmissão de malária na região, principalmente nos municípios de Gaspar, Indaial e Rodeio.INTRODUCTION: The Amazon region of Brazil is endemic for malaria. In the State of Santa Catarina, malaria was eliminated in the 1980s. Since then, a few sporadic isolated autochthonous cases have occurred. However, because malaria vectors are present within Brazilian territory and extensive endemic areas exist in this country, along with the great mobility of people in tourist areas of Santa Catarina, there is the

Genetic Association for P2X7R rs3751142 and CARD8 rs2043211 Polymorphisms for Susceptibility of Gout in Korean Men: Multi-Center Study.

Science.gov (United States)

Lee, Sung Won; Lee, Shin Seok; Oh, Dong Ho; Park, Dong Jin; Kim, Hyun Sook; Choi, Jung Ran; Chae, Soo Cheon; Yun, Ki Jung; Chung, Won Tae; Choe, Jung Yoon; Kim, Seong Kyu

2016-10-01

The aim of this study was to determine the association between P2X7R rs3751142 and CARD8 rs2043211 polymorphisms and gout susceptibility in male Korean subjects. This study enrolled a total of 242 male patients with gout and 280 healthy controls. The polymorphisms of two individual genes including rs3751142(C>A) in the P2X7R gene and rs2043211(A>T) in the CARD8 gene were assessed using Taq-Man analysis. Statistical analyses were performed using the Chi-square test, Kruskal-Wallis test, and logistic regression analyses. A difference in genotypic frequency of the P2X7R rs3751142 and CARD8 rs2043211 genes was not detected between gout and control patients. Clinical parameters including age, onset age, disease duration, body mass index, and serum uric acid levels were not different among the three genotypes for either P2X7R or CARD8 (P > 0.05 for all). A pair-wise comparison of P2X7R rs3751142 and CARD8 rs2043211 genotype combinations revealed that subjects with the CA P2X7R rs3751142 genotype and the TT CARD8 rs2043211 genotype had a trend toward a higher risk of gout compared to the CC/AA combination (P = 0.056, OR = 2.618, 95% CI 0.975 - 7.031). In conclusion, this study revealed that genetic variability of the P2X7R rs3751142 and CARD8 rs2043211 genes might, in part, be associated with susceptibility for gout.

A readout system for the micro-vertex-detector demonstrator for the CBM experiment at FAIR

Energy Technology Data Exchange (ETDEWEB)

Schrader, Christoph

2011-06-09

The Compressed Baryonic Matter Experiment (CBM) is a fixed target heavy ion experiment currently in preparation at the future FAIR accelerator complex in Darmstadt. The CBM experiment focuses on the measurements of diagnostic probes of the early and dense phase of the fireball at beam energies from 8 up to 45 AGeV. As observables, rare hadronic, leptonic and photonic probes are used, including open charm. Open charm will be identified by reconstructing the secondary decay vertex of the corresponding short lived particles. As the central component for track reconstruction, a detector system based on silicon semiconductor detectors is planned. The first three stations of the Silicon Tracking System (STS) make up the so-called Micro-Vertex-Detector (MVD) operating in moderate vacuum. Because of the well-balanced compromise between an excellent spatial resolution (few {mu}m), low material budget ({proportional_to}50 {mu}m Si), adequate radiation tolerance and readout speed, Monolithic Active Pixel Sensors (MAPS) based on CMOS technology are more suited than any other technology for the reconstruction of the secondary vertex in CBM. A new detector concept has to be developed. Two MVD-Demonstrator modules have been successfully tested with 120 GeV pions at the CERN-SPS. The main topic of this thesis is the development of a control and readout concept of several MVD-Demonstrator modules with a common data acquisition system. In order to achieve the required results a front-end electronics device has been developed which is capable of reading the analogue signals of two sensors on a ex-print cable. The high data rate of the MAPS sensors (1.2 Gbit per second and sensor by 50 MHz and 12 bit ADC resolution) requires a readout system which processes the data on-line in a pipeline to avoid dead times. In order to implement the pipeline processing an FPGA is used, which is located on an additional hardware platform. In order to integrate the MVD-Demonstrator readout board in the

A readout system for the micro-vertex-detector demonstrator for the CBM experiment at FAIR

International Nuclear Information System (INIS)

Schrader, Christoph

2011-01-01

The Compressed Baryonic Matter Experiment (CBM) is a fixed target heavy ion experiment currently in preparation at the future FAIR accelerator complex in Darmstadt. The CBM experiment focuses on the measurements of diagnostic probes of the early and dense phase of the fireball at beam energies from 8 up to 45 AGeV. As observables, rare hadronic, leptonic and photonic probes are used, including open charm. Open charm will be identified by reconstructing the secondary decay vertex of the corresponding short lived particles. As the central component for track reconstruction, a detector system based on silicon semiconductor detectors is planned. The first three stations of the Silicon Tracking System (STS) make up the so-called Micro-Vertex-Detector (MVD) operating in moderate vacuum. Because of the well-balanced compromise between an excellent spatial resolution (few μm), low material budget (∝50 μm Si), adequate radiation tolerance and readout speed, Monolithic Active Pixel Sensors (MAPS) based on CMOS technology are more suited than any other technology for the reconstruction of the secondary vertex in CBM. A new detector concept has to be developed. Two MVD-Demonstrator modules have been successfully tested with 120 GeV pions at the CERN-SPS. The main topic of this thesis is the development of a control and readout concept of several MVD-Demonstrator modules with a common data acquisition system. In order to achieve the required results a front-end electronics device has been developed which is capable of reading the analogue signals of two sensors on a ex-print cable. The high data rate of the MAPS sensors (1.2 Gbit per second and sensor by 50 MHz and 12 bit ADC resolution) requires a readout system which processes the data on-line in a pipeline to avoid dead times. In order to implement the pipeline processing an FPGA is used, which is located on an additional hardware platform. In order to integrate the MVD-Demonstrator readout board in the HADES data

Study of low-mass readout cables for the CBM Silicon Tracking System

Energy Technology Data Exchange (ETDEWEB)

Singla, Minni [Goethe Univ. Frankfurt am Main (Germany); GSI, Darmstadt (Germany); Collaboration: CBM-Collaboration

2013-07-01

The study of thin multi-line readout cables will be reported. The application is the Silicon Tracking System (STS) of the fixed-target heavy-ion experiment Compressed Baryonic Matter (CBM), under design at the forthcoming accelerator centre FAIR in Germany. These cables will bridge the distance between the microstrip sensors and the signal processing electronics placed at the periphery of the silicon tracking stations. Finite element simulations (using the TCAD package RAPHAEL) have been used to optimize the cables towards minimum possible Equivalent Noise Charge (ENC). Various trace geometries and trace materials have been explored. SPICE modelling has been implemented in Sentaurus Device to study the transmission loss in the cables. The simulations have been validated with measurements. Charge loss in cables of different lengths was determined by injecting charge pulses of known amplitude. An optimized cable design is reported yielding minimum ENC, material budget and transmission loss.

Ground-water quality in the Santa Rita, Buellton, and Los Olivos hydrologic subareas of the Santa Ynez River basin, Santa Barbara County, California

Science.gov (United States)

Hamlin, S.N.

1985-01-01

Groundwater quality in the upper Santa Ynez River Valley in Santa Barbara County has degraded due to both natural and anthropogenic causes. The semiarid climate and uneven distribution of rainfall has limited freshwater recharge and caused salt buildup in water supplies. Tertiary rocks supply mineralized water. Agricultural activities (irrigation return flow containing fertilizers and pesticides, cultivation, feedlot waste disposal) are a primary cause of water quality degradation. Urban development, which also causes water quality degradation (introduced contaminants, wastewater disposal, septic system discharge, and land fill disposal of waste), has imposed stricter requirements on water supply quality. A well network was designed to monitor changes in groundwater quality related to anthropogenic activities. Information from this network may aid in efficient management of the groundwater basins as public water supplies, centered around three basic goals. First is to increase freshwater recharge to the basins by conjunctive surface/groundwater use and surface-spreading techniques. Second is to optimize groundwater discharge by efficient timing and spacing of pumping. Third is to control and reduce sources of groundwater contamination by regulating wastewater quality and distribution and, preferably, by exporting wastewaters from the basin. (USGS)

Impact of metabolic syndrome on ST segment resolution after thrombolytic therapy for acute myocardial infarction

Directory of Open Access Journals (Sweden)

Ayşe Saatçı Yaşar

2010-09-01

Full Text Available Objectives: It has been shown that metabolic syndrome is associated with poor short-term outcome and poor long-term survival in patients with acute myocardial infarction. We aimed to investigate the effect of metabolic syndrome on ST segment resolution in patients received thrombolytic therapy for acute myocardial infarction.Materials and methods: We retrospectively analyzed 161 patients, who were admitted to our clinics with acute ST-elevated-myocardial infarction and received thrombolytic therapy within 12 hours of chest pain. Metabolic syndrome was diagnosed according to National Cholesterol Education Program Adult Treatment Panel III criteria. Resolution of ST segment elevation was assessed on the baseline and 90-minute electrocardiograms. ST segment resolution ≥70% was defined as complete resolution.Results: Metabolic syndrome was found in 56.5% of patients. The proportion of patients with metabolic syndrome who achieved complete ST segment resolution after thrombolysis was significantly lower than that of patients without metabolic syndrome (32.9% versus 58.6%, p=0.001. On multivariate analysis metabolic syndrome was the only independent predictor of ST segment resolution (p=0.01, Odds ratio=2.543, %95 CI:1.248-5.179Conclusion: The patients with metabolic syndrome had lower rates of complete ST segment resolution after thrombolytic therapy for acute myocardial infarction. This finding may contribute to the higher morbidity and mortality of patients with metabolic syndrome.

Design Report for Isolated RS-485 Bus Node

Science.gov (United States)

2016-07-01

TERMS Android , RS-485, isolated, USB, smartphone 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT UU 18. NUMBER...controlled wired RS-485 network. The Android -based smartphone or tablet is used in conjunction with a USB to serial bridge to operate as the bus master in...the system. The Android device operates in USB Host mode and communicates to the RS-485 bus as if a single peripheral on the USB bus. 15. SUBJECT

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

DEFF Research Database (Denmark)

Sparsø, T; Andersen, G; Nielsen, T

2007-01-01

to metabolic traits (mainly fasting hypertriacylglycerolaemia) and traits related to pancreatic beta cell function. METHODS: The polymorphism was genotyped in 16,853 Danes using Taqman allelic discrimination. Association was analysed in case-control studies and quantitative trait analyses. We also analysed...... the possible interactive effect between the GCK -30G>A polymorphism and the GCKR rs780094 variant on metabolic traits. RESULTS: The minor GCKR A-allele of rs780094 is associated with an increased level of fasting serum triacylglycerol (p = 6 x 10(-14)), impaired fasting (p = 0.001) and OGTT-related insulin...... release (p = 3 x 10(-6)), reduced homeostasis model assessment of insulin resistance (p = 0.0004), WHO-defined dyslipidaemia (p = 6 x 10(-9)) and a modestly decreased risk of type 2 diabetes (p = 0.01). Significantly increased fasting serum insulin concentrations were demonstrated when analysing the GCK...

Track reconstruction algorithms for the CBM experiment at FAIR

International Nuclear Information System (INIS)

Lebedev, Andrey; Hoehne, Claudia; Kisel, Ivan; Ososkov, Gennady

2010-01-01

The Compressed Baryonic Matter (CBM) experiment at the future FAIR accelerator complex at Darmstadt is being designed for a comprehensive measurement of hadron and lepton production in heavy-ion collisions from 8-45 AGeV beam energy, producing events with large track multiplicity and high hit density. The setup consists of several detectors including as tracking detectors the silicon tracking system (STS), the muon detector (MUCH) or alternatively a set of Transition Radiation Detectors (TRD). In this contribution, the status of the track reconstruction software including track finding, fitting and propagation is presented for the MUCH and TRD detectors. The track propagation algorithm takes into account an inhomogeneous magnetic field and includes accurate calculation of multiple scattering and energy losses in the detector material. Track parameters and covariance matrices are estimated using the Kalman filter method and a Kalman filter modification by assigning weights to hits and using simulated annealing. Three different track finder algorithms based on track following have been developed which either allow for track branches, just select nearest hits or use the mentioned weighting method. The track reconstruction efficiency for central Au+Au collisions at 25 AGeV beam energy using events from the UrQMD model is at the level of 93-95% for both detectors.

[Appropriateness admissions to the Department of Internal Medicine of the Hospital de Santa Luzia (Elvas) evaluated by the AEP (Appropriateness Evaluation Protocol)].

Science.gov (United States)

Cordero, A; Aguila, J; Massalana, A; Escoto, V; Lopes, L; Susano, R

2004-01-01

The authors analyse the appropriateness admissions to the Internal Medicine ward of the Hospital de Santa Luzia (Elvas). A retrospective study was performed during 6 months of 2001, using the Appropriateness Evaluation Protocol (AEP). Non-appropriateness admissions were found in 19% (CI95%: 16-22), and this group of patients had less mean age (63 + 16 vs 69 + 16; p <0.01), and less mean days of admission (7.1 + 6 vs 9.3 + 7; p <0.01) than group with appropriateness admissions. Appropriateness admissions were mainly found in patients admitted from the emergency room (86% vs 49%; p <0.001). Most of patients with non-appropriate admissions were admitted to undergo diagnostic tests (44%; CI95%: 35-53), or to be referred to other medical centres for specialized study and/or treatment (12%; CI95%: 6-18).

RS485 optical router for HIRFL-CSR

International Nuclear Information System (INIS)

Zhang Shuocheng; Wang Dan; Jing Lan; Qiao Weimin

2007-01-01

A communication equipment-RS485 optical router has been developed to satisfy requirements of control system communication network of HIRFL-CSR (Heavy Ion Research Facility at Lanzhou-Cooling Storage Ring). The equipment is compatible with multiple communication protocols, such as Ethernet, RS232 and RS485 standard. It can be used to setup the RS485 communication network quickly and connected to the Ethernet easily. The fiber optical interface is introduced to facilitate the connection with the network of industrial Fiber Optics Communication (FOC), which expands the application field of the equipment in a large extent. This paper introduces the details of the equipment, including the design of the circuit and software, features of the equipment and how it works in the whole control system network. Its application in the HIRFL-CSR control system shows that the equipment is in accordance with the general requirement of automatic control communication system. It could also be used in other industrial automatic control fields. (authors)

Breeding and trade of wildlife in Santa Catarina state, Brazil

Directory of Open Access Journals (Sweden)

VV Kuhnen

Full Text Available The wildlife trade is becoming increasingly more relevant in discussions concerning conservation biology and the sustainable management of natural resources. The aim of this study was to document the trade and breeding of wildlife in Santa Catarina state, in southern Brazil. Data was collected from annual reports (1996-2008 of wildlife breeders which were sent to IBAMA. By the end of 2008, there were 79 wildlife breeders and 11 wildlife traders distributed in Santa Catarina. Commercial breeding accounted for the highest number of breeders (51%. In total, there are 213 species of wild animals bred in the state: 177 birds, 19 mammals and 17 reptiles. Of these, 48% are native to Santa Catarina, 32% occur in other Brazilian states and 20% are exotic to Brazil. Nine percent of the species bred are vulnerable or endangered. It was observed that some breeders reported breeding unauthorized species. Altogether, 93 species are bred illegally by 19 breeders. Of these species, 48 are native to Santa Catarina and three are classified as vulnerable or in danger of extinction. We hope the data presented in this paper contributes to the development of conservation strategies and conscious use of wildlife resources in Brazil.

La racionalidad apasionada. Acercamiento a la relación razón y amor en la obra "Camino de Perfección" de Santa Teresa de ávila (1515-1582

Directory of Open Access Journals (Sweden)

Agustina Serrano P.

2005-01-01

Full Text Available Santa Teresa de ávila es una de las grandes figuras de la mística del Siglo de Oro Español. Pablo VI la declara Doctora de la Iglesia el 27 de septiembre de 1970. Este hecho supone que el puesto y la función de la mujer en la Iglesia quedaron afectados cuando se declaró a Santa Teresa Doctora de la Iglesia. Camino de Perfección es la primera obra impresa de Santa Teresa, en el año 1583 quiere ser un libro guía para las comunidades. Es un itinerario de conversión recorrido con una determinada "racionalidad apasionada" que desenmascara todo lo que no está al servicio del Reino. El presente estudio pretende ayudar a detectar la racionalidad teológica de Teresa desde la relación razón y amor en su obra Camino de perfección. En él se comienza a descubrir la propia sistematicidad del pensar de esta autora. Teresa ha ido vertiendo sus ideas respecto a la realidad de todo lo humano. Lo hace de un modo experiencial y sin atenerse, demasiado, a las normas de uso de los grandes conceptos en su épocaSt. Theresa of Avila is one of the great figures of the mysticism of the Spanish "Golden Age". Paul VI declared her a Doctor of the Church on September 27th, 1970. This fact presupposes that the place and function of women in the Church were influenced when St. Theresa was declared Doctor of the Church. Road of Perfection is the first printed work of St. Theresa's, in the year 1583, and was intended to be a guide for communities. It is an itinerary of conversion traveled through with a determined "passionate rationality" that unmasks everything not at the service of the Kingdom. The present study intends to help detect the theological rationality of Theresa from the reason-love relationship in her work Road of Perfection. In it the author's own systematic thought begins to be discovered, depositing her ideas in relation to the reality of all that is human. She does this in an experiential way and without overly depending upon the norms of the

[Santa Claus is perceived as reliable and friendly: results of the Danish Christmas 2013 survey].

Science.gov (United States)

Amin, Faisal Mohammad; West, Anders Sode; Jørgensen, Carina Sleiborg; Simonsen, Sofie Amalie; Lindberg, Ulrich; Tranum-Jensen, Jørgen; Hougaard, Anders

2013-12-02

Several studies have indicated that the population in general perceives doctors as reliable. In the present study perceptions of reliability and kindness attributed to another socially significant archetype, Santa Claus, have been comparatively examined in relation to the doctor. In all, 52 randomly chosen participants were shown a film, where a narrator dressed either as Santa Claus or as a doctor tells an identical story. Structured interviews were then used to assess the subjects' perceptions of reliability and kindness in relation to the narrator's appearance. We found a strong inclination for Santa Claus being perceived as friendlier than the doctor (p = 0.053). However, there was no significant difference in the perception of reliability between Santa Claus and the doctor (p = 0.524). The positive associations attributed to Santa Claus probably cause that he is perceived friendlier than the doctor who may be associated with more serious and unpleasant memories of illness and suffering. Surprisingly, and despite him being an imaginary person, Santa Claus was assessed as being as reliable as the doctor.

A common polymorphism rs3781637 in MTNR1B is associated with type 2 diabetes and lipids levels in Han Chinese individuals

Directory of Open Access Journals (Sweden)

Lu Daru

2011-04-01

Full Text Available Abstract Background Several studies have shown that common variants in the MTNR1B gene were associated with fasting glucose level and type 2 diabetes. The purpose of this study was to examine whether tagging single nucleotide polymorphisms (SNPs in the MTNR1B region were associated with type 2 diabetes and related traits in a Han Chinese population. Methods We investigated the association of polymorphisms in the MTNR1B gene with type 2 diabetes by employing a case-control study design (1118 cases and 1161 controls. Three tagging SNPs (rs10830963, rs3781637, and rs1562444 with R2>0.8 and minor allele frequency>0.05 across the region of the MTNR1B gene were studied. Genotyping was performed by matrix-assisted laser desorption/ionization time-of-flight mass spectroscopy using a MassARRAY platform. Results The polymorphism rs3781637 was associated with type 2 diabetes adjusted for age, sex and body mass index (BMI in the additive model and recessive model (OR = 1.22, 95% CI 1.01-1.46, p = 0.038 and OR = 2.81, 95% CI 1.28-6.17, p = 0.01, respectively. In the non-diabetic controls, rs3781637 was nominally associated with plasma triglyceride, total cholesterol and low density lipoprotein cholesterol (LDL-C levels in the recessive model (p = 0.018, 0.008 and 0.038, respectively. After adjustment for multiple comparisons, the associations of rs3781637 with total cholesterol and LDL-C remained significant in the recessive model (the empirical p = 0.024 and 0.045, respectively, but the association between rs3781637 and triglyceride became non-significant (the empirical p = 0.095. The associations of rs10830963 and rs1562444 with type 2 diabetes and related traits were not significant in the additive, dominant and recessive models. Conclusions The rs3781637 A/G polymorphism of the MTNR1B gene is associated with type 2 diabetes, plasma, total cholesterol and LDL-C levels in the Han Chinese population.

Ecotourism: The Santa Elena Rainforest Project.

Science.gov (United States)

Wearing, Stephen

1993-01-01

Describes an ecotourism project in which the community of Santa Elena, Costa Rica, are developing a rainforest reserve on government land leased permanently to the local high school. Discusses the impact of the project on the community's economy and environment. (Contains 30 references.) (MDH)

Differences in symptoms, first medical contact and pre-hospital delay times between patients with ST- and non-ST-elevation myocardial infarction.

Science.gov (United States)

Ängerud, Karin H; Sederholm Lawesson, Sofia; Isaksson, Rose-Marie; Thylén, Ingela; Swahn, Eva

2017-11-01

In ST-elevation myocardial infarction, time to reperfusion is crucial for the prognosis. Symptom presentation in myocardial infarction influences pre-hospital delay times but studies about differences in symptoms between patients with ST-elevation myocardial infarction and non-ST-elevation myocardial infarction are sparse and inconclusive. The aim was to compare symptoms, first medical contact and pre-hospital delay times in patients with ST-elevation myocardial infarction and non-ST-elevation myocardial infarction. This multicentre, observational study included 694 myocardial infarction patients from five hospitals. The patients filled in a questionnaire about their pre-hospital experiences within 24 h of hospital admittance. Chest pain was the most common symptom in ST-elevation myocardial infarction and non-ST-elevation myocardial infarction (88.7 vs 87.0%, p=0.56). Patients with cold sweat (odds ratio 3.61, 95% confidence interval 2.29-5.70), jaw pain (odds ratio 2.41, 95% confidence interval 1.04-5.58), and nausea (odds ratio 1.70, 95% confidence interval 1.01-2.87) were more likely to present with ST-elevation myocardial infarction, whereas the opposite was true for symptoms that come and go (odds ratio 0.58, 95% confidence interval 0.38-0.90) or anxiety (odds ratio 0.52, 95% confidence interval 0.29-0.92). Use of emergency medical services was higher among patients admitted with ST-elevation myocardial infarction. The pre-hospital delay time from symptom onset to first medical contact was significantly longer in non-ST-elevation myocardial infarction (2:05 h vs 1:10 h, p=0.001). Patients with ST-elevation myocardial infarction differed from those with non-ST-elevation myocardial infarction regarding symptom presentation, ambulance utilisation and pre-hospital delay times. This knowledge is important to be aware of for all healthcare personnel and the general public especially in order to recognise symptoms suggestive of ST-elevation myocardial infarction and

Multirate Filter Bank Representations of RS and BCH Codes

Directory of Open Access Journals (Sweden)

Van Meerbergen Geert

2008-01-01

Full Text Available Abstract This paper addresses the use of multirate filter banks in the context of error-correction coding. An in-depth study of these filter banks is presented, motivated by earlier results and applications based on the filter bank representation of Reed-Solomon (RS codes, such as Soft-In Soft-Out RS-decoding or RS-OFDM. The specific structure of the filter banks (critical subsampling is an important aspect in these applications. The goal of the paper is twofold. First, the filter bank representation of RS codes is now explained based on polynomial descriptions. This approach allows us to gain new insight in the correspondence between RS codes and filter banks. More specifically, it allows us to show that the inherent periodically time-varying character of a critically subsampled filter bank matches remarkably well with the cyclic properties of RS codes. Secondly, an extension of these techniques toward the more general class of BCH codes is presented. It is demonstrated that a BCH code can be decomposed into a sum of critically subsampled filter banks.

Multirate Filter Bank Representations of RS and BCH Codes

Directory of Open Access Journals (Sweden)

Marc Moonen

2009-01-01

Full Text Available This paper addresses the use of multirate filter banks in the context of error-correction coding. An in-depth study of these filter banks is presented, motivated by earlier results and applications based on the filter bank representation of Reed-Solomon (RS codes, such as Soft-In Soft-Out RS-decoding or RS-OFDM. The specific structure of the filter banks (critical subsampling is an important aspect in these applications. The goal of the paper is twofold. First, the filter bank representation of RS codes is now explained based on polynomial descriptions. This approach allows us to gain new insight in the correspondence between RS codes and filter banks. More specifically, it allows us to show that the inherent periodically time-varying character of a critically subsampled filter bank matches remarkably well with the cyclic properties of RS codes. Secondly, an extension of these techniques toward the more general class of BCH codes is presented. It is demonstrated that a BCH code can be decomposed into a sum of critically subsampled filter banks.

Recent recoveries of archaeological ceramics on Santa Isabel, central Solomon Islands

International Nuclear Information System (INIS)

Carter, M.J.; Roe, D.; Keopo, J.

2012-01-01

Recent field investigations on Santa Isabel in the Central Solomon Islands have revealed the presence of archaeological pottery in both terrestrial and intertidal contexts. Preliminary dating results and comparative stylistic analyses of sherds provide evidence to suggest an antiquity of ceramics in northwest Isabel spanning the late Holocene to the recent historic past. These research outcomes expand the known distribution of pottery within the Solomon Islands and provide new knowledge about the prehistory of Santa Isabel. Here we describe the Santa Isabel ceramics, and suggest several implications of the research for current settlement models of the Solomon Islands and for our understanding of the variability in the archaeological record of mid- to late-Holocene ceramic distribution throughout the region. (author). 24 refs., 7 figs.

Hydrologic and geochemical characterization of the Santa Rosa Plain watershed, Sonoma County, California

Science.gov (United States)

Nishikawa, Tracy

2013-01-01

The Santa Rosa Plain is home to approximately half of the population of Sonoma County, California, and faces growth in population and demand for water. Water managers are confronted with the challenge of meeting the increasing water demand with a combination of water sources, including local groundwater, whose future availability could be uncertain. To meet this challenge, water managers are seeking to acquire the knowledge and tools needed to understand the likely effects of future groundwater development in the Santa Rosa Plain and to identify efficient strategies for surface- and groundwater management that will ensure the long-term viability of the water supply. The U.S. Geological Survey, in cooperation with the Sonoma County Water Agency and other stakeholders in the area (cities of Cotati, Rohnert Park, Santa Rosa, and Sebastopol, town of Windsor, Cal-American Water Company, and the County of Sonoma), undertook this study to characterize the hydrology of the Santa Rosa Plain and to develop tools to better understand and manage the groundwater system. The objectives of the study are: (1) to develop an updated assessment of the hydrogeology and geochemistry of the Santa Rosa Plain; (2) to develop a fully coupled surface-water and groundwater-flow model for the Santa Rosa Plain watershed; and (3) to evaluate the potential hydrologic effects of alternative groundwater-management strategies for the basin. The purpose of this report is to describe the surface-water and groundwater hydrology, hydrogeology, and water-quality characteristics of the Santa Rosa Plain watershed and to develop a conceptual model of the hydrologic system in support of the first objective. The results from completing the second and third objectives will be described in a separate report.

Time-based Cellular Automaton track finder for the CBM experiment

International Nuclear Information System (INIS)

Akishina, Valentina; Kisel, Ivan

2015-01-01

The future heavy-ion experiment CBM (FAIR/GSI, Darmstadt, Germany) will focus on the measurement of rare probes at interaction rates up to 10 MHz with data flow of up to 1 TB/s. The beam will provide free stream of particles without bunch structure. That requires full online event reconstruction and selection not only in space, but also in time, so- called 4D event building and selection. This is a task of the First-Level Event Selection (FLES) package. The FLES reconstruction and selection package consists of several modules: track finding, track fitting, short-lived particles finding, event building and event selection. The input data are distributed within the FLES farm in a form of so-called time-slices, in which time length is proportional to a compute power of a processing node. A time-slice is reconstructed in parallel between cores within a CPU, thus minimising communication between CPUs. After all tracks of the whole time-slice are found and fitted, they are collected into clusters of tracks originated from common primary vertices. After that short-lived particles are found and the full event building process is finished. (paper)

Santa Lucia River basin. Development of water resources; Cuenca del Rio Santa Lucia.Desarrollo de los recursos hidricos

Energy Technology Data Exchange (ETDEWEB)

NONE

1970-07-01

The main objective of this study was to orient the development of water resources of the Santa Lucia River basin to maximum benefit in accordance with the priorities established by Government in relation to the National Development Plans

Association between rs3087243 and rs231775 polymorphism within the cytotoxic T-lymphocyte antigen 4 gene and Graves' disease: a case/control study combined with meta-analyses

Science.gov (United States)

Dai, Yu; Zeng, Tianshu; Xiao, Fei; Chen, Lulu; Kong, Wen

2017-01-01

We conducted a case/control study to assess the impact of SNP rs3087243 and rs231775 within the CTLA4 gene, on the susceptibility to Graves' disease (GD) in a Chinese Han dataset (271 cases and 298 controls). The frequency of G allele for rs3087243 and rs231775 was observed to be significantly higher in subjects with GD than in control subjects (p = 0.005 and p = 0.000, respectively). After logistic regression analysis, a significant association was detected between SNP rs3087243 and GD in the additive and recessive models. Similarly, association for the SNP rs231775 could also be detected in the additive model, dominant model and recessive model. A meta-analysis, including 27 published datasets along with the current dataset, was performed to further confirm the association. Consistent with our case/control results, rs3087243 and rs231775 showed a significant association with GD in all genetic models. Of note, ethnic stratification revealed that these two SNPs were associated with susceptibility to GD in populations of both Asian and European descent. In conclusion, our data support that the rs3087243 and rs231775 polymorphisms within the CTLA4 gene confer genetic susceptibility to GD. PMID:29299173

Polymorphisms rs12998 and rs5780218 in KiSS1 Suppressor Metastasis Gene in Mexican Patients with Breast Cancer

Directory of Open Access Journals (Sweden)

Edhit Guadalupe Cruz Quevedo

2015-01-01

Full Text Available Aims. KiSS1 is a metastasis suppressor gene associated with inhibition of cellular chemotaxis and invasion attenuating the metastasis in melanoma and breast cancer cell lines. Along the KiSS-1 gene at least 294 SNPs have been described; however the association of these polymorphisms as genetic markers for metastasis in breast cancer studies has not been investigated. Here we describe two simple PCR-RFLPs protocols to identify the rs5780218 (9DelT and the rs12998 (E20K KiSS1 polymorphisms and the allelic, genotypic, and haplotypic frequencies in Mexican general population (GP and patients with benign breast disease (BBD or breast cancer (BC. Results. The rs5780218 polymorphism was individually associated with breast cancer (P=0.0332 and the rs12998 polymorphism shows statistically significant differences when GP versus case (BC and BBD groups were compared (P<0.0001. The H1 Haplotype (G/- occurred more frequently in BC group (0.4256 whereas H2 haplotype (G/T was the most prevalent in BBD group (0.4674. Conclusions. Our data indicated that the rs5780218 polymorphism individually confers susceptibility for development of breast cancer in Mexican population and a possible role as a genetic marker in breast cancer metastasis for H1 haplotype (Wt/variant in KiSS1 gene must be analyzed in other populations.

Online selection of short-lived particles on many-core computer architectures in the CBM experiment at FAIR

International Nuclear Information System (INIS)

Zyzak, Maksym

2016-01-01

Modern experiments in heavy ion collisions operate with huge data rates that can not be fully stored on the currently available storage devices. Therefore the data flow should be reduced by selecting those collisions that potentially carry the information of the physics interest. The future CBM experiment will have no simple criteria for selecting such collisions and requires the full online reconstruction of the collision topology including reconstruction of short-lived particles. In this work the KF Particle Finder package for online reconstruction and selection of short-lived particles is proposed and developed. It reconstructs more than 70 decays, covering signals from all the physics cases of the CBM experiment: strange particles, strange resonances, hypernuclei, low mass vector mesons, charmonium, and open-charm particles. The package is based on the Kalman filter method providing a full set of the particle parameters together with their errors including position, momentum, mass, energy, lifetime, etc. It shows a high quality of the reconstructed particles, high efficiencies, and high signal to background ratios. The KF Particle Finder is extremely fast for achieving the reconstruction speed of 1.5 ms per minimum-bias AuAu collision at 25 AGeV beam energy on single CPU core. It is fully vectorized and parallelized and shows a strong linear scalability on the many-core architectures of up to 80 cores. It also scales within the First Level Event Selection package on the many-core clusters up to 3200 cores. The developed KF Particle Finder package is a universal platform for short- lived particle reconstruction, physics analysis and online selection.

Online selection of short-lived particles on many-core computer architectures in the CBM experiment at FAIR

Energy Technology Data Exchange (ETDEWEB)

Zyzak, Maksym

2016-07-07

Modern experiments in heavy ion collisions operate with huge data rates that can not be fully stored on the currently available storage devices. Therefore the data flow should be reduced by selecting those collisions that potentially carry the information of the physics interest. The future CBM experiment will have no simple criteria for selecting such collisions and requires the full online reconstruction of the collision topology including reconstruction of short-lived particles. In this work the KF Particle Finder package for online reconstruction and selection of short-lived particles is proposed and developed. It reconstructs more than 70 decays, covering signals from all the physics cases of the CBM experiment: strange particles, strange resonances, hypernuclei, low mass vector mesons, charmonium, and open-charm particles. The package is based on the Kalman filter method providing a full set of the particle parameters together with their errors including position, momentum, mass, energy, lifetime, etc. It shows a high quality of the reconstructed particles, high efficiencies, and high signal to background ratios. The KF Particle Finder is extremely fast for achieving the reconstruction speed of 1.5 ms per minimum-bias AuAu collision at 25 AGeV beam energy on single CPU core. It is fully vectorized and parallelized and shows a strong linear scalability on the many-core architectures of up to 80 cores. It also scales within the First Level Event Selection package on the many-core clusters up to 3200 cores. The developed KF Particle Finder package is a universal platform for short- lived particle reconstruction, physics analysis and online selection.

Track measurement in the high multiplicity environment at the CBM Experiment

International Nuclear Information System (INIS)

Ghosh, Pradeep

2014-01-01

In the Compressed Baryonic Matter (CBM) Experiment at FAIR, the Silicon Tracking System (STS) will perform track reconstruction and momentum determination of the charged particles created in interactions of heavy-ion beams with nuclear targets. The STS will consist of 8 tracking layers located at distances between 30 cm and 100 cm downstream of the target inside the 1 Tm magnetic dipole field. An ultra-low material budget is required to achieve momentum resolution of the order of Δp/p = 1%. Therefore, the front-end electronics is placed outside the physics aperture. The active volume of the STS is built from 300 μm thick double-sided silicon microstrip sensors mounted onto lightweight carbon fiber support ladders. The sensors will be read out through ultra-thin micro-cables with fast self-triggering electronics at the periphery of the stations where also other infrastructure such as cooling can be placed. In this paper, the development status of the detector system, highlighting the overview of the STS layout, tracking algorithm and performance simulations are presented.

Parallel 4-Dimensional Cellular Automaton Track Finder for the CBM Experiment

International Nuclear Information System (INIS)

Akishina, Valentina; Kisel, Ivan

2016-01-01

The CBM experiment (FAIR/GSI, Darmstadt, Germany) will focus on the measurement of rare probes at interaction rates up to 10 MHz with data flow of up to 1 TB/s. It requires a novel read-out and data-acquisition concept with self-triggered electronics and free-streaming data. In this case resolving different collisions is not a trivial task and event building must be performed in software online. That requires full online event reconstruction and selection not only in space, but also in time, so-called 4D event building and selection. This is a task of the First-Level Event Selection (FLES). The FLES reconstruction and selection package consists of several modules: track finding, track fitting, short-lived particles finding, event building and event selection. The Cellular Automaton (CA) track finder algorithm was adapted towards time-slice-based reconstruction and included into the CBMROOT framework. In this article, we describe the modification done to the algorithm, as well as the performance of the developed time-based approach. (paper)

Bi-phase CO{sub 2} cooling of the CBM STS detector

Energy Technology Data Exchange (ETDEWEB)

Lavrik, Evgeny [Physikalisches Institut der Universitaet Tuebingen (Germany); Collaboration: CBM-Collaboration

2016-07-01

The Compressed Baryonic Matter (CBM) experiment aims to study the properties of nuclear matter at high net-baryon densities. The Silicon Tracking System (STS) is the key detector to reconstruct charged particle tracks created in heavy-ion interactions. The foreseen interaction rate of up to 10 MHz requires radiation hard detectors as well as efficient cooling of the silicon sensors. To avoid thermal runaway the system must be kept at -5 C or below all the time. This is rather challenging because the overall thermal load in the 2 m{sup 3} STS enclosure is up to 40 kW. Because of these requirements liquid CO{sub 2} is used as a cooling agent as it is superior in terms of volumetric heat transfer coefficient compared to other agents. This contribution shows the thermal simulations and measurement results of the STS front-end electronic boxes as well as an overview of 1 kW TRACI-XL cooling plant developed at GSI and its use to perform thermal measurements of a fully heat loaded STS quarter station.

South Fork of the Santa Clara River, Santa Clarita Valley, California. Supplement.

Science.gov (United States)

1985-01-01

designed as a broad - crested weir to pass the maximum probable flood (PF) with a peak of 24,500 ofs. The spillway crest length of 100 feet and the...well as from the Miocene Topanga sandstone and the Modelo shale found near the crest of the Santa Susana Mountains in Aliso and Rice Canyons. Fossil...440 1.5 .IN THE AREA. 1I0.050: DRAINAGE AREA IS QUITE RUGGED, WITH SHARP RIDGES 4.4 600 1.3 .050 AND NARROW, STEEP CANYONS THROUGH WHICH WATERCOURSES

Relationships between FTO rs9939609, MC4R rs17782313, and PPARγ rs1801282 polymorphisms and the occurrence of selected metabolic and hormonal disorders in middle-aged and elderly men – a preliminary study

Directory of Open Access Journals (Sweden)

Rotter I

2016-11-01

Full Text Available Iwona Rotter,1 Karolina Skonieczna-Żydecka,2 Danuta Kosik-Bogacka,3 Grażyna Adler,2 Aleksandra Rył,4 Maria Laszczyńska4 1Department of Medical Rehabilitation, 2Department of Gerontobiology, 3Department of Biology and Medical Parasitology, 4Department of Histology and Developmental Biology, Pomeranian Medical University, Szczecin, Poland Purpose: Metabolic disorders, including MetS, obesity, and lipid disorders, may be related to genetic factors. Metabolic disorders are associated with decreased TS levels in aging men. The aim of this study was to evaluate the relationship between FTO rs9939609, MC4R rs17782313, and PPARɣ rs1801282 polymorphisms and the presence of MetS and its components, the concurrent lipid disorders, as well as sex hormone concentrations. Subjects and methods: This study involved 272 men of Caucasian descent aged 50–75 years. Lipid profile, including TCh, LDL, HDL, and TG, was evaluated by spectrophotometric method. Anthropometric measurements concerned WC and blood pressure. MetS was diagnosed according to the criteria of the IDF. Sex hormone profile, including TST, FTS, E2, DHEAS, and SHBG, was examined using enzyme-linked immunosorbent assay. Polymorphisms within FTO, MC4R, and PPARɣ genes were identified using polymerase chain reaction-restriction fragments length polymorphism. Results: This study did not show links between the analyzed genetic polymorphisms and the presence of MetS, T2DM, HT, and obesity. However, higher concentrations of TCh and LDL were found in men with the FTO rs9939609 polymorphism in the recessive mode of inheritance (P=0.03 and P=0.05, respectively. Lower WC was found to be associated with MC4R rs17782313 gene inherited in the same model (P=0.005. Conclusion: FTO rs9939609, MC4R rs17782313, and PPARɣ rs1801282 polymorphisms seem to have little effect on the incidence of metabolic malfunctions and no effect on androgen-related disorders in the examined middle-aged and elderly men

The KFParticle package for the fast particle reconstruction in ALICE and CBM

Energy Technology Data Exchange (ETDEWEB)

Zyzak, Maksym; Kisel, Ivan; Kulakov, Igor [Goethe Univ. Frankfurt am Main (Germany); Frankfurt Institute for Advanced Studies, Frankfurt am Main (Germany); GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Vassiliev, Iourii [Goethe Univ. Frankfurt am Main (Germany); GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Collaboration: CBM-Collaboration

2013-07-01

Modern heavy-ion experiments operate with very high data rates and track multiplicities collecting petabytes of data, therefore the speed of the reconstruction algorithms is crucial both for the online and offline data analysis. The KFParticle package for short-lived particles reconstruction has been developed and is actively used both in the CBM and ALICE experiments. The package is based on the Kalman filter mathematics and has rich functionality. It is geometry independent and can be used in other experiments too. Almost all modern servers are equipped with many or multi-core processors, which contain SIMD modules. The KFParticle has been SIMDized, which gives the additional speedup factor of 3-5. KFParticle allows to reconstruct about 50 decay channels achieving speed of 1.5 ms per Au+Au mbias collisions at 25 AGeV on a single core. The package has been parallelized between cores and shows strong linear scalability on servers with up to 80 logical cores.

The peptidylglycine-α-amidating monooxygenase (PAM) gene rs13175330 A>G polymorphism is associated with hypertension in a Korean population.

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Yoo, Hye Jin; Kim, Minjoo; Kim, Minkyung; Chae, Jey Sook; Lee, Sang-Hyun; Lee, Jong Ho

2017-11-21

Peptidylglycine-α-amidating monooxygenase (PAM) may play a role in the secretion of atrial natriuretic peptide (ANP), which is a hormone involved in the maintenance of blood pressure (BP). The objective of the present study was to determine whether PAM is a novel candidate gene for hypertension (HTN). A total of 2153 Korean participants with normotension and HTN were included. Genotype data were obtained using the Korean Chip. The rs13175330 polymorphism of the PAM gene was selected from the ten single nucleotide polymorphisms (SNPs) most strongly associated with BP. The presence of the G allele of the PAM rs13175330 A>G SNP was associated with a higher risk of HTN after adjustments for age, sex, BMI, smoking, and drinking [OR 1.607 (95% CI 1.220-2.116), p = 0.001]. The rs13175330 G allele carriers in the HTN group treated without antihypertensive therapy (HTN w/o therapy) had significantly higher systolic and diastolic BP than the AA carriers, whereas the G allele carriers in the HTN group treated with antihypertensive therapy (HTN w/ therapy) showed significantly higher diastolic BP. Furthermore, rs13175330 G allele carriers in the HTN w/o therapy group had significantly increased levels of insulin, insulin resistance, and oxidized low-density lipoprotein (LDL) and significantly decreased LDL-cholesterol levels and LDL particle sizes compared to the AA carriers. These results suggest that the PAM rs13175330 A>G SNP is a novel candidate gene for HTN in the Korean population. Additionally, the PAM rs13175330 G allele might be associated with insulin resistance and LDL atherogenicity in patients with HTN.

Violencia física contra la mujer en Santa Fe de Bogotá: prevalencia y factores asociados

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Klevens Joanne

2001-01-01

Full Text Available Objetivos. Estimar la magnitud del problema de la violencia conyugal que afecta a las mujeres que acuden a los servicios de salud pública en Santa Fe de Bogotá, Colombia, e identificar los factores asociados con el riesgo de ser agredidas físicamente. Métodos. Se analizaron los datos recolectados desde septiembre de 1998 hasta septiembre de 1999 mediante entrevistas de las 3 971 mujeres con niños menores de 6 meses de edad, que solicitaron consulta por diversas causas pediátricas (control del niño sano, vacunación o morbilidad del menor o fueron atendidas por parto en la red de servicios de salud pública en la localidad de Suba, Santa Fe de Bogotá, Colombia. De la muestra indicada, 10 mujeres rehusaron participar y 804 no tenían compañero, por lo cual se excluyeron de los análisis. Resultados. De las 3 157 participantes que convivían con un compañero íntimo, 26,5% informaron que habían sido abofeteadas o empujadas por su compañero actual y 13,3% que habían sido agredidas gravemente por medio de golpes con el puño cerrado, patadas, golpes con algún objeto, "golpizas" y amenazas con un cuchillo o arma de fuego. Además de lo anterior, 26,2% de ellas indicaron que su compañero les imponía alguna prohibición. En los análisis bivariados, la violencia se asoció significativamente con menos escolaridad y menores ingresos (P < 0,001, mayor número de hijos (P < 0,001, mayor tiempo de unión con el compañero actual (P < 0,001, mayor frecuencia de conflicto con la pareja (P < 0,001, ausencia de otros familiares en el hogar (P < 0,01, historia de maltrato en la familia de origen (P < 0,001 y prohibiciones por parte del compañero (P < 0,001. La frecuencia del conflicto con la pareja y las prohibiciones fueron los factores más fuertemente asociados con la violencia, según el análisis multivariado. Conclusiones. Los servicios de salud pública son un buen lugar para detectar a las víctimas de la violencia intrafamiliar. Deben

Effect of Acute, Subacute, and Repeated Exposure to High Altitude (5050 m on Psychomotor Vigilance

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Matiram Pun

2018-06-01

Full Text Available Aim: High altitude (HA hypoxia may affect cognitive performance and sleep quality. Further, vigilance is reduced following sleep deprivation. We investigated the effect on vigilance, actigraphic sleep indices, and their relationships with acute mountain sickness (AMS during very HA exposure, acclimatization, and re-exposure.Methods: A total of 21 healthy altitude-naive individuals (25 ± 4 years; 13 females completed 2 cycles of altitude exposure separated by 7 days at low altitude (LA, 520 m. Participants slept at 2900 m and spent the day at HA, (5050 m. We report acute altitude exposure on Day 1 (LA vs. HA1 and after 6 days of acclimatization (HA1 vs. HA6. Vigilance was quantified by reaction speed in the 10-min psychomotor vigilance test reaction speed (PVT-RS. AMS was evaluated using the Environmental Symptoms Questionnaire Cerebral Score (AMS-C score. Nocturnal rest/activity was recorded to estimate sleep duration using actigraphy.Results: In Cycle 1, PVT-RS was slower at HA1 compared to LA (4.1 ± 0.8 vs. 4.5 ± 0.6 s-1, respectively, p = 0.029, but not at HA6 (4.6 ± 0.7; p > 0.05. In Cycle 2, PVT-RS at HA1 (4.6 ± 0.7 and HA6 (4.8 ± 0.6 were not different from LA (4.8 ± 0.6, p > 0.05 and significantly greater than corresponding values in Cycle 1. In both cycles, AMS scores were higher at HA1 than at LA and HA6 (p < 0.05. Estimated sleep durations (TST at LA, 1st and 5th nights were 431.3 ± 28.7, 418.1 ± 48.6, and 379.7 ± 51.4 min, respectively, in Cycle 1 and they were significantly reduced during acclimatization exposures (LA vs. 1st night, p > 0.05; LA vs. 5th night, p = 0.012; and 1st vs. 5th night, p = 0.054. LA, 1st and 5th nights TST in Cycle 2 were 477.5 ± 96.9, 430.9 ± 34, and 341.4 ± 32.2, respectively, and we observed similar deteriorations in TST as in Cycle 1 (LA vs. 1st night, p > 0.05; LA vs. 5th night, p = 0.001; and 1st vs. 5th night, p < 0.0001. At HA1, subjects who reported higher AMS-C scores exhibited slower

Epidemiological study of facial fractures at the Oral and Maxillofacial Surgery Service, Santa Casa de Misericordia Hospital Complex, Porto Alegre - RS - Brazil.

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Zamboni, Rodrigo Andrighetti; Wagner, João Carlos Birnfeld; Volkweis, Maurício Roth; Gerhardt, Eduardo Luis; Buchmann, Elissa Muller; Bavaresco, Caren Serra

2017-01-01

to investigate the incidence and etiology of face trauma with diagnosis of facial fracture treated at the Buccomaxillofacial Surgery and Traumatology Service of the Santa Casa de Misericórdia Hospital Complex in Porto Alegre. we conducted a cross-sectional, retrospective epidemiological study of 134 trauma victims with 153 facial fractures. the male gender was the most affected (86.6%) and the incidence was higher in the age group from 21 to 30 years. The main etiology was assault (38.8%), followed by motor vehicle accidents (14.2%), motorcycle accidents (13.4%), falls (9%), road accidents (6.7%), sports accidents (5.2%), work accidents (5.2%), firearm injuries (4.5%) and cycling accidents (3%). The most frequent fractures were those of the zygomatic complex (44.5%), followed by fractures of the mandible (42.5%), maxillary bone (5.2%), nasal bones (4.5%) and zygomatic arch (3.3%). the fractures of the zygomatic complex and the mandible were the ones with the highest incidence in the facial traumas, having physical assaults as their main cause.

Epidemiological study of facial fractures at the Oral and Maxillofacial Surgery Service, Santa Casa de Misericordia Hospital Complex, Porto Alegre - RS - Brazil

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Rodrigo Andrighetti Zamboni

Full Text Available ABSTRACT Objectives: to investigate the incidence and etiology of face trauma with diagnosis of facial fracture treated at the Buccomaxillofacial Surgery and Traumatology Service of the Santa Casa de Misericórdia Hospital Complex in Porto Alegre. Methods: we conducted a cross-sectional, retrospective epidemiological study of 134 trauma victims with 153 facial fractures. Results: the male gender was the most affected (86.6% and the incidence was higher in the age group from 21 to 30 years. The main etiology was assault (38.8%, followed by motor vehicle accidents (14.2%, motorcycle accidents (13.4%, falls (9%, road accidents (6.7%, sports accidents (5.2%, work accidents (5.2%, firearm injuries (4.5% and cycling accidents (3%. The most frequent fractures were those of the zygomatic complex (44.5%, followed by fractures of the mandible (42.5%, maxillary bone (5.2%, nasal bones (4.5% and zygomatic arch (3.3%. Conclusion: the fractures of the zygomatic complex and the mandible were the ones with the highest incidence in the facial traumas, having physical assaults as their main cause.

CBM Reading, Mathematics, and Written Expression at the Secondary Level: Examining Latent Composite Relations among Indices and Unique Predictions with a State Achievement Test

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Codding, Robin S.; Petscher, Yaacov; Truckenmiller, Adrea

2015-01-01

A paucity of research has examined the utility of curriculum-based measurement (CBM) for data-based decision making at the secondary level. As schools move to multitiered systems of service delivery, it is conceivable that multiple screening measures will be used that address various academic subject areas. The value of including different CBM…

A Functional Polymorphism (rs10817938 in the XPA Promoter Region Is Associated with Poor Prognosis of Oral Squamous Cell Carcinoma in a Chinese Han Population.

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Chunhai Gao

Full Text Available Single nucleotide polymorphisms of XPA gene have been studied in several cancers such as rs10817938, rs2808668. However, the role of XPA polymorphisms in patients with oral squamous cell carcinoma (OSCC remains unclear. Thus, we analyzed the association of XPA polymorphisms with OSCC risk, clinicopathological characteristics and prognosis in the present study. TaqMan genotyping was used to evaluate the frequency of rs10817938, rs2808668 polymorphisms in OSCC patients. The prognostic significance of these polymorphisms was evaluated using Kaplan-Meier curves, Log-Rank analyses, and the Cox proportional hazard model. Luciferase reporter assay, RT-PCR and western blot were used to determine whether rs10817938 could influence transcription activity and XPA expression. The results showed that individuals carrying TC and CC genotypes had significantly greater risk of developing OSCC (OR = 1.42, 95% CI 1.04-1.93; OR = 2.75, 95% CI 1.32-5.71, respectively when compared with wild-type TT genotype at rs10817938. OSCC patients with C allele at rs10817938 were more susceptible to lymph metastases, poor pathological differentiation and late TNM stage (OR = 1.67, 95% CI 1.17-2.37; OR = 1.64, 95% CI 1.18-2.28; OR = 1.54, 95% CI 1.11-2.14; respectively. A significant gene-environment interaction between smoking and CC genotype at rs10817938 was observed (COR = 3.60, 95% CI 1.20-10.9 and data also showed that OSCC patients with CC genotype and C allele had worse survival (p<0.001 for both. The T to C substitution at rs10817938 significantly decreased transcription activity of XPA gene, XPA mRNA and protein were also decreased in individuals with C allele at rs10817938. In addition, no significant association of rs2808668 polymorphism with OSCC risk, prognosis could be observed. In conclusion, the present study showed that XPA rs10817938 polymorphism is a functional SNP in vitro and in vivo and a biomarker for poor prognosis in OSCC patients.

Avaliação de populações de Butia capitata de Santa Vitória do Palmar Performance of populations of Butia capitata of Santa Vitória do Palmar

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Elisane Schwartz

2010-09-01

Full Text Available O gênero Butia pertence à família Arecaceae e possui cinco espécies com ocorrência no Rio Grande do Sul. A espécie Butia capitata está recebendo atenção especial, não só pelo seu uso no consumo in natura como também em formas processadas. No entanto, mesmo sendo uma espécie que tem sua utilização registrada desde os tempos pré-históricos, vem sendo explorada apenas de modo extrativista, como a maioria das espécies de frutíferas nativas. Além disso, a espécie está seriamente comprometida em médio prazo pela ausência de regeneração natural e com risco muito alto de extinção num futuro próximo. Nesse sentido, o objetivo deste trabalho foi comparar os frutos, a partir de parâmetros químicos e físicos, e também observar os dados produtivos das plantas de três populações de butiazeiros do município de Santa Vitória do Palmar-RS. Os dados foram obtidos em experimentos conduzidos na safra de 2005/2006 e na safra de 2006/2007, em três propriedades localizadas em Santa Vitória do Palmar. Os resultados permitiram verificar que as propriedades e ou variações genéticas entre as populações de Butia capitata avaliadas propiciaram variabilidade para duração do ciclo, coloração da epiderme dos frutos, volume de suco produzido, relação entre sólidos solúveis totais e acidez titulável, características biométricas de fruto e produtividade anual. Uma das populações, denominada Celina, apresentou maior produtividade e rendimento industrial. As populações Celina e São José apresentaram as melhores características biométricas de fruto. A população Aguiar apresentou a melhor relação entre sólidos solúveis totais e acidez titulável.The genus Butia belongs to the Arecaceae family and shows five species occurring in Rio Grande de Sul. The specie Butia capitata requires special attention, not just for its use as fresh consumption but also as processed product. However, even having its use recorded since

Tumor necrosis factor −308 polymorphism (rs1800629) is associated with mortality and ventilator duration in 1057 Caucasian patients

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Watanabe, Eizo; Zehnbauer, Barbara A.; Oda, Shigeto; Sato, Yasunori; Hirasawa, Hiroyuki; Buchman, Timothy G.

2012-01-01

Purpose Management of sepsis in critically ill patients remains difficult and requires prolonged intensive care. Genetic testing has been proposed as a strategy to identify patients at risk for adverse outcome of critical illnesses. Therefore, we wished to determine the influence of heredity on predisposition to poor outcome and on duration of ventilator support of intensive care unit (ICU) patients. Methods A study was conducted from July 2001 to December 2005 in heterogeneous population of patients from 12 US ICUs represented by the Genetic Predisposition to Severe Sepsis (GenPSS) archive. In 1057 Caucasian critically ill patients with SAPS II probability of survival of >0.2 in the US, six functional single nucleotide polymorphisms in relation to inflammatory cytokines and innate immunity (rs1800629, rs16944, rs1800795, rs1800871, rs2569190, and rs909253) were evaluated in terms of mortality and ventilator free days. Results The AA homozygote of TNF(−308) (rs1800629) was most over-represented in the deceased patient group (P = 0.015 with recessive model). The carriage of the TNF(−308)* AA genotype showed significantly higher odds ratio of 2.67(1.29–5.55) (P = 0.008) after adjustment with the covariates. However, the presence of 1, 2, or 3 acute organ dysfunctions was larger prognostic factors for the adverse outcome (OR(95%CI) = 2.98(2.00–4.45), 4.01(2.07–7.77), or 19.95(4.99–79.72), P < 0.001 for all). Kaplan–Mayer plot on ventilator duration of TNF(−308)* AA patient significantly diverged from that of TNF(−308)* (GG + GA) ((AA v GG + GA), Adjusted HR(95%CI) = 2.53(1.11–5.79) with Cox regression, P = 0.028). Conclusions TNF(−308)* AA is significantly associated with susceptibility to adverse outcome and to longer ventilator duration. Therefore, heredity likely affects both predisposition to ICU prognosis as well as the resource utilization. PMID:22749237

STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C polymorphisms influence the risk of developing juvenile idiopathic arthritis in Han Chinese patients.

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Fan, Zhi-Dan; Wang, Fei-Fei; Huang, Hui; Huang, Na; Ma, Hui-Hui; Guo, Yi-Hong; Zhang, Ya-Yuan; Qian, Xiao-Qing; Yu, Hai-Guo

2015-01-01

Juvenile idiopathic arthritis (JIA) is a common autoimmune disease characterized by environmental influences along with several predisposing genes in the pathogenesis. The protein tyrosine phosphatase nonreceptor 22 (PTPN22) and signal transducer and activator of transcription factor 4 (STAT4) have been recognized as susceptibility genes for numerous autoimmune diseases. Associations of STAT4 rs7574865 G/T and PTPN22 (rs2488457 G/C and rs2476601 C/T) polymorphisms with JIA have repeatedly been replicated in several Caucasian populations. The aim of this study was to investigate the influence of three polymorphisms mentioned above on the risk of developing JIA in Han Chinese patients. Genotyping was performed on a total of 137 Chinese patients with JIA (JIA group) and 150 sex and age frequency-matched healthy volunteers (Control group). The single-nucleotide polymorphisms (SNP) were determined by using direct sequencing of PCR-amplified products. There were significant differences of PTPN22 rs2488457 G/C and STAT4 rs7574865 G/T polymorphisms between both groups. However, no significant difference was observed in distribution frequencies of PTPN22 rs2476601 polymorphism. The association with the PTPN22 rs2488457 G/C polymorphism remained significant in the stratifications by age at onset, ANA status, splenomegaly, lymphadenectasis and involvement joints. As with the STAT4 rs7574865 G/T polymorphisms, the enthesitis-related arthritis and presence of hepatomegaly had strong effect on the association. Our data strengthen STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C polymorphisms as susceptibility factors for JIA.

STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C polymorphisms influence the risk of developing juvenile idiopathic arthritis in Han Chinese patients.

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Zhi-Dan Fan

Full Text Available Juvenile idiopathic arthritis (JIA is a common autoimmune disease characterized by environmental influences along with several predisposing genes in the pathogenesis. The protein tyrosine phosphatase nonreceptor 22 (PTPN22 and signal transducer and activator of transcription factor 4 (STAT4 have been recognized as susceptibility genes for numerous autoimmune diseases. Associations of STAT4 rs7574865 G/T and PTPN22 (rs2488457 G/C and rs2476601 C/T polymorphisms with JIA have repeatedly been replicated in several Caucasian populations. The aim of this study was to investigate the influence of three polymorphisms mentioned above on the risk of developing JIA in Han Chinese patients. Genotyping was performed on a total of 137 Chinese patients with JIA (JIA group and 150 sex and age frequency-matched healthy volunteers (Control group. The single-nucleotide polymorphisms (SNP were determined by using direct sequencing of PCR-amplified products. There were significant differences of PTPN22 rs2488457 G/C and STAT4 rs7574865 G/T polymorphisms between both groups. However, no significant difference was observed in distribution frequencies of PTPN22 rs2476601 polymorphism. The association with the PTPN22 rs2488457 G/C polymorphism remained significant in the stratifications by age at onset, ANA status, splenomegaly, lymphadenectasis and involvement joints. As with the STAT4 rs7574865 G/T polymorphisms, the enthesitis-related arthritis and presence of hepatomegaly had strong effect on the association. Our data strengthen STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C polymorphisms as susceptibility factors for JIA.

mir-126 rs4636297 and TGFβRI rs334348 functional gene variants are associated with susceptibility to endometriosis and its severity.

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Sepahi, Neda; Kohan, Leila; Jahromi, Athar Rasekh; Daneshbod, Yahya; Hoveidi, Elahe Nimi

2017-06-01

microRNAs (miRNAs) are negative regulators in a variety of cellular processes that occur in endometriosis. Therefore, functional polymorphisms in miRNA and miRNA binding sites may affect gene expression and contribute to susceptibility of endometriosis. In this study, we evaluated the association of two miRNA related polymorphisms, mir-126 rs4636297 and TGFβRI rs334348, with endometriosis risk and its severity. This case-control study was done on 157 endometriosis patients and 252 healthy women as a control group. Tetra amplification refractory mutation system-polymerase chain reaction (tetra-ARMS PCR) was designed to determine the polymorphisms. Our finding showed significant differences in genotype frequency of mir-126 rs4636297 between the groups (χ 2  = 6.26, p = 0.044). A significant protection against endometriosis was found for mir-126 rs4636297 in allele (G versus A allele: OR = 0.695, 95% CI = 0.519-0.931, p = 0.015) and genotype (GG versus AA genotype: OR = 0.451, 95%CI = 0.233-0.873, p = 0.018). Significant association was also observed between the A allele and severity of endometriosis (OR = 0.478, 95%CI = 0.297-0.768, p = 0.002). Moreover, we found a significant association between AA genotype with the risk of endometriosis (OR = 0.493, 95%CI = 0.250-0.970, p = 0.041) and its severity (OR = 0.240, 95%CI = 0.065-0.883, p = 0.032) regarding TGFβRI rs334348 polymorphism. These finding suggest that, for the first time, mir-126 rs4636297 and TGFβRI rs334348 polymorphisms may influence individual's susceptibility to endometriosis and its severity.

Zoneamento e identificação de Fusarium spp. causadores de podridão de raízes em plantios de erva-mate (Ilex paraguariensis A. St.-Hil. na região do vale do Taquarí, RS

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Igor Poletto

2006-01-01

Full Text Available In 2004, symptoms of root rot disease were observed in erva-mate plantings in high areas of Region Taquari Valley, RS. With the help of EMATER, the municipal districts presenting plantings with symptoms were surveyed. In 10% of the affected plantings, root samples were collected and sent for analysis at the Plant Disease Laboratory at the Department of Plant Protection/CCR/UFSM. Five different species of at fungus Fusarium associated with the disease were isolated and identified: Fusarium oxysporum, Fusarium solani, Fusarium decemcellulare, Fusarium tabacinum and Fusarium tricinctum. All species were pathogenic when inoculated in erva-mate plants (Ilex paraguariensis A. St.-Hil.. At the moment of sampling, information about the management of the erva-mate plantings was obtained and the similarity between the symptoms presented in erva-mate and in agronomic crops discussed, as well as hypotheses on the origin of the inoculum of Fusarium spp. that infected the erva-mate plantings.

Análise do cariótipo de Apuleia leiocarpa (Vog. Macbr. Analysis of Apuleia leiocarpa (Vog. Macbr. karyotype

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Neiva Maria Frizon Auler

1999-03-01

Full Text Available Estudos citogenéticos da Apuleia leiocarpa foram realizados com o objetivo de determinar e montar o cariótipo da espécie. As sementes utilizadas foram coletadas na localidade de Cerrito, município de Santa Maria - RS. A pesquisa foi conduzida no Laboratório de Citogenética Vegetal e Biotecnologia do Departamento de Biologia da Universidade federal de Santa Maria - RS, nos anos de 1996 - 1997. Em metáfases de mitose foi encontrada uma variação no número de cromossomos de 20 a 28, sugerindo ser a Apuleia leiocarpa uma leguminosa com capacidade de polissomatia. O número de cromossomos da espécie é 2n = 2x = 26, distribuídos na fórmula cariotípica 20m + 4 sm + 2 t.Cytogenetic studies of Apuleia leiocarpa were carried out in order to determine and arrange the species karyotype. Seeds were collected in Cerrito, Santa Maria - RS. The research was developed at the Laboratory of Vegetal Cytogenetics and Biotechnology of the Biology Department at the Federal University of Santa Maria - RS, during 1996 and 1997. A variation in the number of chromosomes from 20 to 28 was found in metaphases of mitosis. Such variation suggests that Apuleia leiocarpa is a leguminous with polysomy capacity. The chromosomal number of the species is 2n = 2x = 26, distributed in the karyotypic formula 20m + 4 sm + 2 t.

Association of ADORA1 rs2228079 and ADORA2A rs5751876 Polymorphisms with Gilles de la Tourette Syndrome in the Polish Population.

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Piotr Janik

Full Text Available Gilles de la Tourette syndrome (GTS is a neurodevelopmental disorder characterized by motor and vocal tics. Hyperactivity of dopaminergic transmission is considered a prime abnormality in the pathophysiology of tics. There are reciprocal antagonistic interactions between adenosine and dopamine transmission. The aim of the study was to analyze the association of two polymorphisms, rs2228079 in ADORA1 and rs5751876 in ADORA2A, with the risk of GTS and co-morbid disorders.A total of 162 Polish GTS patients and 270 healthy persons were enrolled in the study. Two polymorphisms were selected on the basis of knowledge of SNPs frequencies in ADORA1 and ADORA2A. Chi-square test was used for allelic and genotypic association studies. Association of genotypes with age of tic onset was analyzed with Mann-Whitney test. Multivariate logistic regression was used to find independent predictors of GTS risk.We found that the risk of GTS was associated with rs2228079 and rs5751876 polymorphisms. The GG+GT genotypes of rs2228079 in ADORA1 were underrepresented in GTS patients (p = 0.011, whereas T allele of rs5751876 in ADORA2A was overrepresented (p = 0.017. The GG genotype of rs2228079 was associated with earlier age of tic onset (p = 0.046. We found also that the minor allele G of rs2228079 was more frequent in GTS patients with depression as compared to the patients without depression (p = 0.015. Also the genotype GG was significantly more frequent in patients with obsessive compulsive disorder/behavior (OCD/OCB, p = 0.021 and depression (p = 0.032, as compared to the patients without these co-morbidities. The minor allele T frequency of rs5751876 was lower in GTS patients with co-morbid attention deficit hyperactivity disorder (p = 0.022, and TT+TC genotypes were less frequent in the non-OCD anxiety disorder group (p = 0.045.ADORA1 and ADORA2A variants are associated with the risk of GTS, co-morbid disorders, and may affect the age of tic onset.

SEMINÁRIO INTERNACIONAL TURISMO E ARQUEOLOGIA: PATRIMÔNIO CULTURAL E NATURAL –PELOTAS/RS/BRASIL PROMOÇÃO DA REDE INTERINSTITUCIONAL UFPEL-UFSM-IPT PARA O DESENVOLVIMENTO INTEGRADO DA ARQUEOLOGIA, PALEONTOLOGIA,TURISMO CULTURAL, PRESERVAÇÃO E EDUCAÇÃO PA

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Fábio Vergara Cerqueira

2012-09-01

Full Text Available O Seminário Internacional Turismo e Arqueologia: Patrimônio Cultural e Natural  foi idealizado e promovido pela rede interinstitucional estabelecida entre a Universidade Federal de Pelotas (UFPEL, a Universidade Federal de Santa Maria (UFSM e o Instituto Politécnico de Tomar (IPT-Portugal, visando ao desenvolvimento de projetos nas áreas de Arqueologia, Paleontologia, Preservação e Educação Patrimonial e Turismo Cultural. Sua realização ocorreu em Pelotas/RS/Brasil, entre 24 e 27 de Novembro de 2004.

The TT genotype of the STAT4 rs7574865 polymorphism is associated with high disease activity and disability in patients with early arthritis.

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Amalia Lamana

Full Text Available BACKGROUND: The number of copies of the HLA-DRB1 shared epitope, and the minor alleles of the STAT4 rs7574865 and the PTPN22 rs2476601 polymorphisms have all been linked with an increased risk of developing rheumatoid arthritis. In the present study, we investigated the effects of these genetic variants on disease activity and disability in patients with early arthritis. METHODOLOGY AND RESULTS: We studied 640 patients with early arthritis (76% women; median age, 52 years, recording disease-related variables every 6 months during a 2-year follow-up. HLA-DRB1 alleles were determined by PCR-SSO, while rs7574865 and rs2476601 were genotyped with the Taqman 5' allelic discrimination assay. Multivariate analysis was performed using generalized estimating equations for repeated measures. After adjusting for confounding variables such as gender, age and ACPA, the TT genotype of rs7574865 in STAT4 was associated with increased disease activity (DAS28 as compared with the GG genotype (β coefficient [95% confidence interval] = 0.42 [0.01-0.83], p = 0.044. Conversely, the presence of the T allele of rs2476601 in PTPN22 was associated with diminished disease activity during follow-up in a dose-dependent manner (CT genotype = -0.27 [-0.56- -0.01], p = 0.042; TT genotype = -0.68 [-1.64- -0.27], p = 0.162. After adjustment for gender, age and disease activity, homozygosity for the T allele of rs7574865 in STAT4 was associated with greater disability as compared with the GG genotype. CONCLUSIONS: Our data suggest that patients with early arthritis who are homozygous for the T allele of rs7574865 in STAT4 may develop a more severe form of the disease with increased disease activity and disability.

The TT genotype of the STAT4 rs7574865 polymorphism is associated with high disease activity and disability in patients with early arthritis.

Science.gov (United States)

Lamana, Amalia; Balsa, Alejandro; Rueda, Blanca; Ortiz, Ana M; Nuño, Laura; Miranda-Carus, Maria Eugenia; Gonzalez-Escribano, Maria F; Lopez-Nevot, Miguel A; Pascual-Salcedo, Dora; Martin, Javier; González-Álvaro, Isidoro

2012-01-01

The number of copies of the HLA-DRB1 shared epitope, and the minor alleles of the STAT4 rs7574865 and the PTPN22 rs2476601 polymorphisms have all been linked with an increased risk of developing rheumatoid arthritis. In the present study, we investigated the effects of these genetic variants on disease activity and disability in patients with early arthritis. We studied 640 patients with early arthritis (76% women; median age, 52 years), recording disease-related variables every 6 months during a 2-year follow-up. HLA-DRB1 alleles were determined by PCR-SSO, while rs7574865 and rs2476601 were genotyped with the Taqman 5' allelic discrimination assay. Multivariate analysis was performed using generalized estimating equations for repeated measures. After adjusting for confounding variables such as gender, age and ACPA, the TT genotype of rs7574865 in STAT4 was associated with increased disease activity (DAS28) as compared with the GG genotype (β coefficient [95% confidence interval] = 0.42 [0.01-0.83], p = 0.044). Conversely, the presence of the T allele of rs2476601 in PTPN22 was associated with diminished disease activity during follow-up in a dose-dependent manner (CT genotype = -0.27 [-0.56- -0.01], p = 0.042; TT genotype = -0.68 [-1.64- -0.27], p = 0.162). After adjustment for gender, age and disease activity, homozygosity for the T allele of rs7574865 in STAT4 was associated with greater disability as compared with the GG genotype. Our data suggest that patients with early arthritis who are homozygous for the T allele of rs7574865 in STAT4 may develop a more severe form of the disease with increased disease activity and disability.

78 FR 43916 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

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2013-07-22

...) Ave. P, .75 mi. W. of 30th Rd., Little River, 13000580 Santa Fe Trail--Rice County Segment 3, (Santa... MISSOURI St. Charles County Link, Oliver L. and Catherine, House, 1005 Jefferson, St. Charles, 13000584 NEW... Manitowoc County Klingholz, Charles and Herriette, House, 224 Mill Rd., Manitowoc Rapids, 13000587 Waukesha...

The optimal algorithm for Multi-source RS image fusion.

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Fu, Wei; Huang, Shui-Guang; Li, Zeng-Shun; Shen, Hao; Li, Jun-Shuai; Wang, Peng-Yuan

2016-01-01

In order to solve the issue which the fusion rules cannot be self-adaptively adjusted by using available fusion methods according to the subsequent processing requirements of Remote Sensing (RS) image, this paper puts forward GSDA (genetic-iterative self-organizing data analysis algorithm) by integrating the merit of genetic arithmetic together with the advantage of iterative self-organizing data analysis algorithm for multi-source RS image fusion. The proposed algorithm considers the wavelet transform of the translation invariance as the model operator, also regards the contrast pyramid conversion as the observed operator. The algorithm then designs the objective function by taking use of the weighted sum of evaluation indices, and optimizes the objective function by employing GSDA so as to get a higher resolution of RS image. As discussed above, the bullet points of the text are summarized as follows.•The contribution proposes the iterative self-organizing data analysis algorithm for multi-source RS image fusion.•This article presents GSDA algorithm for the self-adaptively adjustment of the fusion rules.•This text comes up with the model operator and the observed operator as the fusion scheme of RS image based on GSDA. The proposed algorithm opens up a novel algorithmic pathway for multi-source RS image fusion by means of GSDA.

Pronóstico De Mesoescala De Un Evento De Noviembre De 2008 En Santa Catarina Mesoscale forescasting of an event of novenber 2008 in Santa Catharina

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Lia Martins Costa do Amaral

2012-12-01

Full Text Available La gran disponibilidad de vapor de agua en los niveles inferiores de la atmósfera, advectada sobre la costa de la provincia de Santa Catarina por el anticiclón semiestacionario del Océano Atlántico, favoreció períodos frecuentes de lluvia durante el mes de noviembre de 2008. La exploración del evento extremo ocurrido en Santa Catarina, que se caracterizó por un intenso bloqueo en niveles altos, se realizó con pronósticos de los modelos del mesoescala MM5 y WRF. Estos modelos fueron procesados con muy alta resolución espacial, abarcando toda la región afectada por el evento severo. La temperatura de la superficie del mar presentaba anomalías positivas de temperatura a lo largo de la costa de Santa Catarina, favoreciendo la transferencia de calor latente hacia la atmósfera, con su posterior advección hacia la zona continental. Los resultados obtenidos con los modelos son consistentes con las observaciones, aunque fuertemente dependientes de la resolución horizontal de los mismos.The large availability of water vapor at low levels of the atmosphere, advected into the coastal region of Santa Catharina State by the Atlantic Ocean semi-stationary anticyclone, provided the frequent and copious rainfall during the November, 2008. One of the most extreme event occurred in Santa Catharina coastal zone, when a quite strong blocking formed at high levels of the atmosphere is explored processing both, the MM5 and WRF mesoscale models. These models were processed with very high spatial resolution domains, covering the entire region affected by the severe event. The sea surface temperature field revealed that there was a large core on Atlantic waters with quite high temperatures along the coast of Santa Catharina, which enhanced the vertical integrated latent heat supply into the continental region by the winds. The models forecasting results showed consistent results with the observations, as well as an indication that coherences are directly

A viable on-chip FPGA configuration memory scrubbing approach for CBM-ToF

Energy Technology Data Exchange (ETDEWEB)

Oancea, Andrei-Dumitru; Stuellein, Christian; Manz, Sebastian; Gebelein, Jano; Kebschull, Udo [Infrastruktur und Rechnersysteme in der Informationsverarbeitung (IRI), Goethe-Universitaet, Senckenberganlage 31, 60325 Frankfurt am Main (Germany); Collaboration: CBM-Collaboration

2015-07-01

The ToF Detector of the CBM Experiment will be equipped with FPGA-based read-out boards (ROBs). These ROBs will be operated in a radiation environment, and therefore need a mitigation mechanism against soft errors in the SRAM-based configuration memories of the FPGAs. The proposed approach combines intrinsic on-chip single upset correction with extrinsic selective frame scrubbing for multiple-bit upsets. The slow control is realized using the GBT-SCA, which is capable of handling interrupts. This enables the new approach of event-driven configuration frame correction. While conventional blind scrubbing leads to a continuous load on the control path, the selective frame scrubbing reduces this load to a minimum. For verification purposes, radiation tests with a proton beam were performed at COSY, Juelich. The occurred soft errors were classified into single and multiple- bit upsets, enabling an estimation of the rate at which extrinsic intervention is necessary.

Quantitative evaluation of pairs and RS steganalysis

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Ker, Andrew D.

2004-06-01

We give initial results from a new project which performs statistically accurate evaluation of the reliability of image steganalysis algorithms. The focus here is on the Pairs and RS methods, for detection of simple LSB steganography in grayscale bitmaps, due to Fridrich et al. Using libraries totalling around 30,000 images we have measured the performance of these methods and suggest changes which lead to significant improvements. Particular results from the project presented here include notes on the distribution of the RS statistic, the relative merits of different "masks" used in the RS algorithm, the effect on reliability when previously compressed cover images are used, and the effect of repeating steganalysis on the transposed image. We also discuss improvements to the Pairs algorithm, restricting it to spatially close pairs of pixels, which leads to a substantial performance improvement, even to the extent of surpassing the RS statistic which was previously thought superior for grayscale images. We also describe some of the questions for a general methodology of evaluation of steganalysis, and potential pitfalls caused by the differences between uncompressed, compressed, and resampled cover images.

The origin of the RS CVn binaries

International Nuclear Information System (INIS)

Biermann, P.

1976-01-01

Six possible origins for the RS CVn binaries are considered based on the following possibilities. RS CVn binaries might now be either pre-main-sequence or post-main-sequence. A pre-main-sequence binary might not always have been a binary but might have resulted from fission of a rapidly rotating single pre-main-sequence star. The main-sequence counterparts might be either single stars or binaries. To decide which of the six origins is possible, the following observed data for the RS CVn binaries are considered: total mass, total angular momentum, lack of observed connection with regions of star formation, large space density, kinematical age, and the visual companion of WW Dra. In addition lifetimes and space densities of single stars and other types of binaries are considered. The only origin possible is that the RS CVn binaries are in a thermal phase following fission of a main-sequence single star. In this explanation the single star had a rapidly rotating core which became unstable due to the core contraction which made it begin to evolve off the main sequence. The present Be stars might be examples of such parent single stars. (Auth.)

Documentation of the Santa Clara Valley regional ground-water/surface-water flow model, Santa Clara Valley, California

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Hanson, R.T.; Li, Zhen; Faunt, C.C.

2004-01-01

The Santa Clara Valley is a long, narrow trough extending about 35 miles southeast from the southern end of San Francisco Bay where the regional alluvial-aquifer system has been a major source of water. Intensive agricultural and urban development throughout the 20th century and related ground-water development resulted in ground-water-level declines of more than 200 feet and land subsidence of as much as 12.7 feet between the early 1900s and the mid-1960s. Since the 1960s, Santa Clara Valley Water District has imported surface water to meet growing demands and reduce dependence on ground-water supplies. This importation of water has resulted in a sustained recovery of the ground-water flow system. To help support effective management of the ground-water resources, a regional ground-water/surface-water flow model was developed. This model simulates the flow of ground water and surface water, changes in ground-water storage, and related effects such as land subsidence. A numerical ground-water/surface-water flow model of the Santa Clara Valley subbasin of the Santa Clara Valley was developed as part of a cooperative investigation with the Santa Clara Valley Water District. The model better defines the geohydrologic framework of the regional flow system and better delineates the supply and demand components that affect the inflows to and outflows from the regional ground-water flow system. Development of the model includes revisions to the previous ground-water flow model that upgraded the temporal and spatial discretization, added source-specific inflows and outflows, simulated additional flow features such as land subsidence and multi-aquifer wellbore flow, and extended the period of simulation through September 1999. The transient-state model was calibrated to historical surface-water and ground-water data for the period 197099 and to historical subsidence for the period 198399. The regional ground-water flow system consists of multiple aquifers that are grouped

An Examination of Test-Retest, Alternate Form Reliability, and Generalizability Theory Study of the easyCBM Reading Assessments: Grade 5. Technical Report #1220

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Lai, Cheng-Fei; Park, Bitnara Jasmine; Anderson, Daniel; Alonzo, Julie; Tindal, Gerald

2012-01-01

This technical report is one in a series of five describing the reliability (test/retest and alternate form) and G-Theory/D-Study research on the easyCBM reading measures, grades 1-5. Data were gathered in the spring of 2011 from a convenience sample of students nested within classrooms at a medium-sized school district in the Pacific Northwest.…

An Examination of Test-Retest, Alternate Form Reliability, and Generalizability Theory Study of the easyCBM Reading Assessments: Grade 2. Technical Report #1217

Science.gov (United States)

Anderson, Daniel; Lai, Cheg-Fei; Park, Bitnara Jasmine; Alonzo, Julie; Tindal, Gerald

2012-01-01

This technical report is one in a series of five describing the reliability (test/retest an alternate form) and G-Theory/D-Study on the easyCBM reading measures, grades 1-5. Data were gathered in the spring of 2011 from the convenience sample of students nested within classrooms at a medium-sized school district in the Pacific Northwest. Due to…

An Examination of Test-Retest, Alternate Form Reliability, and Generalizability Theory Study of the easyCBM Reading Assessments: Grade 1. Technical Report #1216

Science.gov (United States)

Anderson, Daniel; Park, Jasmine, Bitnara; Lai, Cheng-Fei; Alonzo, Julie; Tindal, Gerald

2012-01-01

This technical report is one in a series of five describing the reliability (test/retest/and alternate form) and G-Theory/D-Study research on the easy CBM reading measures, grades 1-5. Data were gathered in the spring 2011 from a convenience sample of students nested within classrooms at a medium-sized school district in the Pacific Northwest. Due…