Sample records for case study-hanaa handheld

  1. LLNL Center for Microtechnology: Capabilities, Customers, Case Study-HANAA (Handheld Nucleic Acid Analyzer)

    Energy Technology Data Exchange (ETDEWEB)

    Mariella, R


    The polymerase chain reaction (PCR) is an enzyme-based chemical reaction that manufactures copies of one or more identifying regions of double-stranded DNA sequences (target sequences). These copies of target DNA are known as ''amplicons''. By creating millions of these copies of the identifying sequences (when they are present!), PCR allows researchers to detect by them, and hence the presence of the relevant organism, with techniques such as electrophoresis, flow cytometry, or spectrometry. Although there are numerous commercial PCR instruments that are designed for bench-top use in a laboratory, the challenges of building a battery-powered instrument that could perform such assays in the field.

  2. Innovation and Integration: Case Studies of Effective Teacher Practices in the Use of Handheld Computers (United States)

    Chavez, Raymond Anthony


    Previous research conducted on the use of handheld computers in K-12 education has focused on how handheld computer use affects student motivation, engagement, and productivity. These four case studies sought to identify effective teacher practices in the integration of handhelds into the curriculum and the factors that affect those practices. The…

  3. Active case finding strategy for chronic obstructive pulmonary disease with handheld spirometry. (United States)

    Kim, Joo Kyung; Lee, Chang Min; Park, Ji Young; Kim, Joo Hee; Park, Sung-Hoon; Jang, Seung Hun; Jung, Ki-Suck; Yoo, Kwang Ha; Park, Yong Bum; Rhee, Chin Kook; Kim, Deog Kyeom; Hwang, Yong Il


    The early detection and diagnosis of chronic obstructive pulmonary disease (COPD) is critical to providing appropriate and timely treatment. We explored a new active case-finding strategy for COPD using handheld spirometry.We recruited subjects over 40 years of age with a smoking history of more than 10 pack-years who visited a primary clinic complaining of respiratory symptoms. A total of 190 of subjects were enrolled. Medical information was obtained from historical records and physical examination by general practitioners. All subjects had their pulmonary function evaluated using handheld spirometry with a COPD-6 device. Because forced expiratory volume in 6 seconds (FEV6) has been suggested as an alternative to FVC, we measured forced expiratory volume in 1 second (FEV1)/FEV6 for diagnosis of airflow limitation. All subjects were then referred to tertiary referral hospitals to complete a "Could it be COPD?" questionnaire, handheld spiromtery, and conventional spirometry. The results of each instrument were compared to evaluate the efficacy of both handheld spirometry and the questionnaire.COPD was newly diagnosed in 45 (23.7%) patients. According to our receiver-operating characteristic (ROC) curve analysis, sensitivity and specificity were maximal when the FEV1/FEV6 ratio was less than 77%. The area under the ROC curve was 0.759. The sensitivity, specificity, positive predictive value, and negative predictive value were 72.7%, 77.1%, 50%, and 90%, respectively. The area under the ROC curve of respiratory symptoms listed on the questionnaire ranged from 0.5 to 0.65, which indicates that there is almost no difference compared with the results of handheld spirometry.The present study demonstrated the efficacy of handheld spirometry as an active case-finding tool for COPD in a primary clinical setting. This study suggested that physicians should recommend handheld spirometry for people over the age of 40, who have a smoking history of more than 10 pack

  4. Handheld Versus Wearable Interaction Design for Professionals - A Case Study of Hospital Service Work

    DEFF Research Database (Denmark)

    Stisen, Allan; Blunck, Henrik; Kjærgaard, Mikkel Baun;


    service work. This explorative study was conducted with 4 experienced hospital orderlies who interacted with an application across two wearable concepts, and one handheld smartphone in five scenarios in a hospital environment. The interaction was video recorded with a chest-mounted video afterwards semi...... aspects to aid designers of next generation wearable designs for hospital service work....

  5. Hand-held tidal breathing nasal nitric oxide measurement--a promising targeted case-finding tool for the diagnosis of primary ciliary dyskinesia.

    Directory of Open Access Journals (Sweden)

    June Kehlet Marthin

    Full Text Available BACKGROUND: Nasal nitric oxide (nNO measurement is an established first line test in the work-up for primary ciliary dyskinesia (PCD. Tidal breathing nNO (TB-nNO measurements require minimal cooperation and are potentially useful even in young children. Hand-held NO devices are becoming increasingly widespread for asthma management. Therefore, we chose to assess whether hand-held TB-nNO measurements reliably discriminate between PCD, and Healthy Subjects (HS and included Cystic Fibrosis (CF patients as a disease control group known to have intermediate nNO levels. METHODS: In this cross sectional, single centre, single occasion, proof-of-concept study in children and adults with PCD and CF, and in HS we compared feasibility, success rates, discriminatory capacity, repeatability and agreement between a hand-held electrochemical device equipped with a nNO software application sampling at flow rates 2 ml/s or 5 ml/s, and two stationary chemiluminescence devices, applying both tidal breathing and velum closure techniques. RESULTS: Measurements were done in 16 PCD patients, 21 patients with CF and 20 HS aged between 3.8 and 60.9 years. Hand-held TB-nNO showed high success rate (96.5-100% vs. velum closure nNO techniques (70.2-89.5%. Hand-held TB-nNO sampling at flow rate 5 ml/s showed equally high discriminative power (PCD vs. HS [p<0.0001] and PCD vs. CF [p<0.0001] and reaching close to 100% sensitivity and specificity, superior repeatability (CV% = 10% and equal limits of agreement compared to TB-nNO by stationary devices and even compared to velum closure sampling. CONCLUSION: Hand-held TB-nNO discriminates significantly between PCD, CF and HS and shows promising potential as a widespread targeted case-finding tool for PCD, although further studies are warranted before implementation.

  6. New Clothing for Handheld Devices (United States)

    Roman, Harry T.


    Clothing is influenced by many factors, trends, and social happenings. Much of what is worn today had utilitarian roots in the past. In the activitiy presented in this article, students will have the opportunity to redesign clothing for new trends, in this case, the explosion of handheld electronic devices.

  7. Handheld-computers

    NARCIS (Netherlands)

    Ramaekers, P.; Huiskes, J.


    Het Proefstation voor de Varkenshouderij onderzoekt de meerwaarde van 'handheld'-computers (handcomputers) voor de registratie van ziekten en behandelingen ten opzichte van de schriftelijke registratie.

  8. Hand-held tidal breathing nasal nitric oxide measurement--a promising targeted case-finding tool for the diagnosis of primary ciliary dyskinesia

    DEFF Research Database (Denmark)

    Marthin, June Kehlet; Nielsen, Kim Gjerum


    BACKGROUND: Nasal nitric oxide (nNO) measurement is an established first line test in the work-up for primary ciliary dyskinesia (PCD). Tidal breathing nNO (TB-nNO) measurements require minimal cooperation and are potentially useful even in young children. Hand-held NO devices are becoming increa...

  9. Universal handheld micropipette (United States)

    Beroz, Justin; Hart, A. John


    The handheld micropipette is the most ubiquitous instrument for precision handling of microliter-milliliter liquid volumes, which is an essential capability in biology and chemistry laboratories. The range of one pipette is typically adjustable up to 10-fold its minimum volume, requiring the use and maintenance of multiple pipettes for liquid handling across larger ranges. Here we propose a design for a single handheld pipette adjustable from 0.1 μl to 1000 μl (i.e., 104-fold) which spans the range of an entire suite of current commercial pipettes. This is accomplished by placing an elastic diaphragm between the existing pipette body and tip, thereby de-amplifying its native volume range while maintaining its simple manual operating procedure. For proof-of-concept, we adapted a commercial pipette (100-1000 μl nominal range) with a selection of rubber sheets to function as the diaphragms and confirmed the accuracy and precision of drawn volumes are within international ISO-8655 standards across the entire 104-fold volume range. The presence of the diaphragms introduces a nonlinear mechanical behavior and a time-dependency due to heat transfer, however, by model and experiment, these are redressed so as to maintain the pipette's accuracy and precision.

  10. Handheld THz security imaging (United States)

    Duling, Irl N.


    Terahertz energy, with its ability to penetrate clothing and non-conductive materials, has held much promise in the area of security scanning. Millimeter wave systems (300 GHz and below) have been widely deployed. These systems have used full two-dimensional surface imaging, and have resulted in privacy concerns. Pulsed terahertz imaging, can detect the presence of unwanted objects without the need for two-dimensional photographic imaging. With high-speed waveform acquisition it is possible to create handheld tools that can be used to locate anomalies under clothing or headgear looking exclusively at either single point waveforms or cross-sectional images which do not pose a privacy concern. Identification of the anomaly to classify it as a potential threat or a benign object is also possible.

  11. Handheld CAT Video Game Project (United States)

    National Aeronautics and Space Administration — The proposed project is to design, develop and fabricate a handheld video game console for astronauts during long space flight. This portable hardware runs...

  12. Handheld Microfluidic Blood Ananlyzer Project (United States)

    National Aeronautics and Space Administration — Nanohmics proposes to develop a handheld blood analyzer for micro- and hypo-gravity missions. The prototype instrument will combine impedance analysis with optical...

  13. Pyxis handheld polarimetric imager (United States)

    Chenault, David B.; Pezzaniti, J. Larry; Vaden, Justin P.


    The instrumentation for measuring infrared polarization signatures has seen significant advancement over the last decade. Previous work has shown the value of polarimetric imagery for a variety of target detection scenarios including detection of manmade targets in clutter and detection of ground and maritime targets while recent work has shown improvements in contrast for aircraft detection and biometric markers. These data collection activities have generally used laboratory or prototype systems with limitations on the allowable amount of target motion or the sensor platform and usually require an attached computer for data acquisition and processing. Still, performance and sensitivity have been steadily getting better while size, weight, and power requirements have been getting smaller enabling polarimetric imaging for a greater or real world applications. In this paper, we describe Pyxis®, a microbolometer based imaging polarimeter that produces live polarimetric video of conventional, polarimetric, and fused image products. A polarization microgrid array integrated in the optical system captures all polarization states simultaneously and makes the system immune to motion artifacts of either the sensor or the scene. The system is battery operated, rugged, and weighs about a quarter pound, and can be helmet mounted or handheld. On board processing of polarization and fused image products enable the operator to see polarimetric signatures in real time. Both analog and digital outputs are possible with sensor control available through a tablet interface. A top level description of Pyxis® is given followed by performance characteristics and representative data.

  14. New generation handheld hyperspectral imager (United States)

    Wu, Huawen (Owen); Li, Hui; Tang, Shengjun


    A miniaturized hyper-spectral imager is enabled with image sensor integrated with dispersing elements in a very compact form factor, removing the need for expensive, moving, bulky and complex optics that have been used in conventional hyper-spectral imagers for decades. The result is a handheld spectral imager that can be installed on miniature UAV drones or conveyor belts in production lines. Eventually, small handhelds can be adapted for use in outpatient medical clinics for point-of-care diagnostics and other in-field applications.

  15. Digital forensics for handheld devices

    CERN Document Server

    Doherty, Eamon P


    Approximately 80 percent of the world's population now owns a cell phone, which can hold evidence or contain logs about communications concerning a crime. Cameras, PDAs, and GPS devices can also contain information related to corporate policy infractions and crimes. Aimed to prepare investigators in the public and private sectors, Digital Forensics for Handheld Devices examines both the theoretical and practical aspects of investigating handheld digital devices. This book touches on all areas of mobile device forensics, including topics from the legal, technical, academic, and social aspects o

  16. Hand-held medical robots. (United States)

    Payne, Christopher J; Yang, Guang-Zhong


    Medical robots have evolved from autonomous systems to tele-operated platforms and mechanically-grounded, cooperatively-controlled robots. Whilst these approaches have seen both commercial and clinical success, uptake of these robots remains moderate because of their high cost, large physical footprint and long setup times. More recently, researchers have moved toward developing hand-held robots that are completely ungrounded and manipulated by surgeons in free space, in a similar manner to how conventional instruments are handled. These devices provide specific functions that assist the surgeon in accomplishing tasks that are otherwise challenging with manual manipulation. Hand-held robots have the advantages of being compact and easily integrated into the normal surgical workflow since there is typically little or no setup time. Hand-held devices can also have a significantly reduced cost to healthcare providers as they do not necessitate the complex, multi degree-of-freedom linkages that grounded robots require. However, the development of such devices is faced with many technical challenges, including miniaturization, cost and sterility, control stability, inertial and gravity compensation and robust instrument tracking. This review presents the emerging technical trends in hand-held medical robots and future development opportunities for promoting their wider clinical uptake.

  17. Handheld Concealed Weapons Detector Development (United States)


    Enforcement, Edward M. Carapezza, Donald Spector, Eds., Proc. SPIE 2938, 110 - 119 (1997). 3. Franklin Felber, Norbert Wild, Scott Nunan , Dennis Breuner... Nunan , D. Breuner, and F. Doft, "Handheld Ultrasound Concealed-Weapons Detector," in Enforcement and Security Technologies, A. Trent DePersia, J. J

  18. Designing automated handheld navigation support

    NARCIS (Netherlands)

    Uluca, D.; Streefkerk, J.W.; Sciacchitano, B.; McCrickard, D.S.


    Map usage on handheld devices suffers from limited screen size and the minimal attention that users can dedicate to them in mobile situations. This work examines effects of automating navigation features like zooming and panning as well as other features such as rotation, path finding and artifact r

  19. The utility of intraoperative handheld gamma camera for detection of sentinel lymph nodes in melanoma

    Energy Technology Data Exchange (ETDEWEB)

    Ozkan, Elgin; Eroglu, Aydan [Ankara University Medical School, Ankara (Turkmenistan)


    Accurate identification of the sentinel lymph node (SLN) is an important prognostic factor for melanoma. In a minority of cases drainage to interval nodal basins, such as the epitrochlear region, are possible. Intraoperative handheld gamma cameras have been used to detect SLNs which are located in different anatomical localizations. In this case we report the utility of an intraoperative handheld gamma camera in the localization of epitrochlear drainage of distal upper extremity melanoma and its impact on surgical procedure.

  20. Handheld ESPI-speckle interferometer

    DEFF Research Database (Denmark)

    Skov Hansen, René


    reference. The reference wave is established by reflecting a part of the diffuse object illumination from a glass plate located just in front of the object. The glass plate is mounted on a piezoelectric translator in order to control the phase of the reference wave when using phase stepping algorithms...... and controlling the phase of the reference wave constitutes a compact "handheld" instrument and eliminates the need for installing extra hardware, such as frame grabber and Digital to Analog converter, in the host computer....

  1. Hand-held Dynamo-metry


    Ploeg, Rutger Jan Otto van der


    This study describes the application of a hand-held dynamometer that was designed to measure muscle strength in normal individuals and neurological patients in a simple way, comparable to manual muscle testing. Zie: Summary

  2. Augmented Reality Simulations on Handheld Computers (United States)

    Squire, Kurt; Klopfer, Eric


    Advancements in handheld computing, particularly its portability, social interactivity, context sensitivity, connectivity, and individuality, open new opportunities for immersive learning environments. This article articulates the pedagogical potential of augmented reality simulations in environmental engineering education by immersing students in…

  3. Handheld ultrasound concealed weapons detector (United States)

    Felber, Franklin S.; Wild, Norbert C.; Nunan, Scott C.; Breuner, Dennis; Doft, Frank


    A handheld, battery-operated prototype of a remove concealed weapons detector has been built and tested. The concealed weapons detector will enable law enforcement and security officers to detect metallic and nonmetallic weapons concealed beneath clothing remotely from beyond arm's length to about 20 feet. These detectors may be used to: (1) allow hands-off, stand-off frisking of suspects for metallic and nonmetallic weapons; and (2) search for metallic and nonmetallic weapons on cooperative subjects at courthouse entrances and other monitored security portals. We have demonstrated that we image weapons concealed under heavy clothing, not just detect them, at ranges up to 15 feet using the same ultrasound frequency (40 kHz) used by commercial rangefinders. The concealed weapons detector operates much as a rangefinder, but at higher peak fluxes and pulse repetition frequencies. The detector alerts the user to concealed weapons audibly and visibly by detecting ultrasound glints above a body/clothing baseline, and by compensating for changing range and attenuation. The detector locates concealed weapons within a 6-inch illuminated spot at 10 feet. The signal processor eliminates any signal from behind the target.

  4. A hand-held ultrasound machine vs. conventional ultrasound machine in the bedside assessment of post-liver transplant patients. (United States)

    Trinquart, Ludovic; Bruno, Onorina; Angeli, Maria Luigia; Belghiti, Jacques; Chatellier, Gilles; Vilgrain, Valérie


    The purpose was to assess the diagnostic accuracy of a hand-held Doppler ultrasound (US) machine for the bedside detection of liver and vascular abnormalities after liver transplantation in the intensive care unit. The IRB approved this study, and written informed consent was obtained from all patients or the patient's legal representative. Any liver transplant recipient at our institution who needed a bedside Doppler US examination in the intensive care unit was eligible. Patients underwent routine grey-scale, colour, and spectral Doppler US examinations of the liver with a conventional machine, which was taken as the reference method, and with a hand-held machine on the same day. Examinations followed one another and were performed in a blinded fashion by two radiologists. Over a 4-month period, 24 consecutive patients (16 men, median age 54 years old; 16 cadaveric and 8 living related right liver transplantations) underwent 43 examinations with both conventional and hand-held machines. Image quality and overall satisfaction scores of grey-scale were lower with the hand-held than with the conventional machine. The hand-held was similar to the conventional machine for assessing the patency of portal veins, hepatic veins and the IVC in all patients but one. The hand-held machine failed to detect signals in the right branch of the hepatic artery and in the hilum in two and one cases, respectively. There was no abnormal hepatic arterial flow with the conventional machine in any of the patients, and the results were the same with the hand-held machine. Total examination time was significantly longer with the hand-held machine. The hand-held US machine had a high diagnostic accuracy for both parenchymal and vascular analyses compared with a conventional US machine in the bedside assessment of post-liver transplant patients.

  5. A Compact Diversity Antenna for Handheld Terminals

    Institute of Scientific and Technical Information of China (English)

    Hai-Lin Xiao; Zai-Ping Nie; Yu-Jing Wu


    The handheld terminals antenna should have a small size, sufficient gain and big bandwidth. In this paper, a compact planar inverted-L diversity antenna for handheld terminals is proposed. Three diversity antennas operating at 2.15 GHz are designed and the effect of important parameters of the proposed antenna is measured. The isolation is found to be better than 13 dB, the usable bandwidth is about 13%. Moreover, the measured radiation patterns are also obtained that the backward radiation is decreased.

  6. 30 CFR 57.12033 - Hand-held electric tools. (United States)


    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Hand-held electric tools. 57.12033 Section 57.12033 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Surface and Underground § 57.12033 Hand-held electric tools. Hand-held electric tools shall not...

  7. 30 CFR 56.12033 - Hand-held electric tools. (United States)


    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Hand-held electric tools. 56.12033 Section 56.12033 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL....12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high...

  8. 30 CFR 56.7053 - Moving hand-held drills. (United States)


    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Moving hand-held drills. 56.7053 Section 56.7053 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Jet Piercing Drilling § 56.7053 Moving hand-held drills. Before hand-held drills are moved from...

  9. Performance of a 6-degree-of-freedom active microsurgical manipulator in handheld tasks. (United States)

    Yang, Sungwook; Wells, Trent S; Maclachlan, Robert A; Riviere, Cameron N


    This paper presents the first experimental results from human users of a new 6-degree-of-freedom handheld micromanipulator. This is the latest prototype of a fully-handheld system, known as "Micron," which performs active compensation of hand tremor for microsurgery. The manipulator is a miniature Gough-Stewart platform incorporating linear ultrasonic motors that provide a cylindrical workspace 4 mm long and 4 mm wide. In addition, the platform allows the possibility of imposing a remote center of motion for controlling motion not only at the tip but also at the entry point in the sclera of the eye. We demonstrate hand tremor reduction in both static and dynamic micromanipulation tasks on a rubber pad. The handheld performance is also evaluated in an artificial eye model while imposing a remote center of motion. In all cases, hand tremor is significantly reduced.


    NARCIS (Netherlands)



    In thirteen major muscle groups of 50 healthy females and 50 males, aged 20-60 years, maximum voluntary contraction was measured with a hand-held dynamometer. The intrasession variation, the left-right variation, and the fifth and fiftieth centile values were calculated. The ratio of two observation

  11. Trajectories in Operating a Handheld Tool (United States)

    Heuer, Herbert; Sulzenbruck, Sandra


    The authors studied the trajectories of the hand and of the tip of a handheld sliding first-order lever in aiming movements. With this kind of tool, straight trajectories of the hand are generally associated with curved trajectories of the tip of the lever and vice versa. Trajectories of the tip of the lever exhibited smaller deviations from…

  12. Handheld Computers in Education: An Industry Perspective (United States)

    van 't Hooft, Mark; Vahey, Philip


    Five representatives from the mobile computing industry provide their perspectives on handhelds in education. While some of their ideas differ, they all agree on the importance of staff development, appropriate curriculum development, and teacher support to create the kinds of personalized learning environments that mobile devices make possible.

  13. Microfluidic MEMS hand-held flow cytometer (United States)

    Grafton, Meggie M. G.; Maleki, Teimour; Zordan, Michael D.; Reece, Lisa M.; Byrnes, Ron; Jones, Alan; Todd, Paul; Leary, James F.


    Due to a number of recent technological advances, a hand-held flow cytometer can be achieved by use of semiconductor illuminators, optical sensors (all battery powered) and sensitive cell markers such as immuno-quantum dot (Qdot) labels. The specific application described is of a handheld blood analyzer that can quickly process a drop of whole, unfractionated human peripheral blood by real-time, on-chip magnetic separation of white blood cells (WBCs) and red blood cells (RBCs) and further fluorescence analysis of Qdot labeled WBC subsets. Various microfluidic patterns were fabricated in PDMS and used to characterize flow of single cells and magnetic deflection of magnetically labeled cells. An LED excitation, avalanche photodiode detection system (SensL Technologies, Ltd., Cork, Ireland) was used for immuno-Qdot detection of WBC subsets. A static optical setup was used to determine the sensitivity of the detection system. In this work we demonstrate: valve-less, on-chip magnetic sorting of immunomagnetically labeled white blood cells, bright Qdot labeling of lymphocytes, and counting of labeled white blood cells. Comparisons of these results with conventional flow cytometric analyses are reported. Sample preparation efficiency was determined by labeling of isolated white blood cells. Appropriate flow rates were determined for optical detection and confirmed with flowing particles. Several enabling technologies required for a truly portable, battery powered, hand-held flow cytometer for use in future point-of-care diagnostic devices have been demonstrated. The combining of these technologies into an integrated handheld instrument is in progress and results on whole blood cell analysis are to be reported in another paper.

  14. Step length estimation using handheld inertial sensors. (United States)

    Renaudin, Valérie; Susi, Melania; Lachapelle, Gérard


    In this paper a novel step length model using a handheld Micro Electrical Mechanical System (MEMS) is presented. It combines the user's step frequency and height with a set of three parameters for estimating step length. The model has been developed and trained using 12 different subjects: six men and six women. For reliable estimation of the step frequency with a handheld device, the frequency content of the handheld sensor's signal is extracted by applying the Short Time Fourier Transform (STFT) independently from the step detection process. The relationship between step and hand frequencies is analyzed for different hand's motions and sensor carrying modes. For this purpose, the frequency content of synchronized signals collected with two sensors placed in the hand and on the foot of a pedestrian has been extracted. Performance of the proposed step length model is assessed with several field tests involving 10 test subjects different from the above 12. The percentages of error over the travelled distance using universal parameters and a set of parameters calibrated for each subject are compared. The fitted solutions show an error between 2.5 and 5% of the travelled distance, which is comparable with that achieved by models proposed in the literature for body fixed sensors only.

  15. Step Length Estimation Using Handheld Inertial Sensors

    Directory of Open Access Journals (Sweden)

    Gérard Lachapelle


    Full Text Available In this paper a novel step length model using a handheld Micro Electrical Mechanical System (MEMS is presented. It combines the user’s step frequency and height with a set of three parameters for estimating step length. The model has been developed and trained using 12 different subjects: six men and six women. For reliable estimation of the step frequency with a handheld device, the frequency content of the handheld sensor’s signal is extracted by applying the Short Time Fourier Transform (STFT independently from the step detection process. The relationship between step and hand frequencies is analyzed for different hand’s motions and sensor carrying modes. For this purpose, the frequency content of synchronized signals collected with two sensors placed in the hand and on the foot of a pedestrian has been extracted. Performance of the proposed step length model is assessed with several field tests involving 10 test subjects different from the above 12. The percentages of error over the travelled distance using universal parameters and a set of parameters calibrated for each subject are compared. The fitted solutions show an error between 2.5 and 5% of the travelled distance, which is comparable with that achieved by models proposed in the literature for body fixed sensors only.

  16. Advances in Antenna Technology for Wireless Handheld Devices

    Directory of Open Access Journals (Sweden)

    Jaume Anguera


    Full Text Available The constant evolution of wireless handheld devices together with the apparition of multiple wireless communication systems fosters the antenna community to design new radiating and measurements systems capable of satisfying the market demands. It is an object of the present paper to provide an overview of the evolution that wireless handheld technology has experienced in the last years. In this sense, a description of the evolution of wireless handheld devices, regulations, challenges in today’s smartphones, and handset characterization is reviewed. Finally, recent advances in antenna technology for wireless handheld or portable devices are presented.

  17. Absorption Related to Hand-Held Devices in Data Mode

    DEFF Research Database (Denmark)

    Andersen, Jørgen Bach; Nielsen, Jesper Ødum; Pedersen, Gert F.


    The human body has an influence on the radiation from handheld devices like smartphones, tablets and laptops, part of the energy is absorbed and the spatial distribution of the radiated part is modified. Previous studies of whole body absorp- tion have mainly been numerical or related to talk mode....... In the present paper an experimental study involving four volunteers and three different devices is performed from 0.5 to 3 GHz. The devices are a laptop, a tablet, and a smartphone all held in the lap. The 3D distribution of radiation is measured. Comparing the integrated power in the case of a person present...... with the device alone allows the determination of the relative absorption in the whole body and the device. In general the absorption varies considerably between devices and as a function of frequency and person. The absorption varies from almost nothing to close to 100%. The shadowing of the body is apparent...

  18. Handheld Technology Acceptance in Radiologic Science Education and Training Programs (United States)

    Powers, Kevin Jay


    The purpose of this study was to explore the behavioral intention of directors of educational programs in the radiologic sciences to adopt handheld devices to aid in managing student clinical data. Handheld devices were described to participants as a technology representing a class of mobile electronic devices including, but not limited to,…

  19. 30 CFR 57.7053 - Moving hand-held drills. (United States)


    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Moving hand-held drills. 57.7053 Section 57.7053 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Rotary Jet Piercing Drilling-Surface and Underground § 57.7053 Moving hand-held drills. Before...

  20. Visual SLAM for Handheld Monocular Endoscope. (United States)

    Grasa, Óscar G; Bernal, Ernesto; Casado, Santiago; Gil, Ismael; Montiel, J M M


    Simultaneous localization and mapping (SLAM) methods provide real-time estimation of 3-D models from the sole input of a handheld camera, routinely in mobile robotics scenarios. Medical endoscopic sequences mimic a robotic scenario in which a handheld camera (monocular endoscope) moves along an unknown trajectory while observing an unknown cavity. However, the feasibility and accuracy of SLAM methods have not been extensively validated with human in vivo image sequences. In this work, we propose a monocular visual SLAM algorithm tailored to deal with medical image sequences in order to provide an up-to-scale 3-D map of the observed cavity and the endoscope trajectory at frame rate. The algorithm is validated over synthetic data and human in vivo sequences corresponding to 15 laparoscopic hernioplasties where accurate ground-truth distances are available. It can be concluded that the proposed procedure is: 1) noninvasive, because only a standard monocular endoscope and a surgical tool are used; 2) convenient, because only a hand-controlled exploratory motion is needed; 3) fast, because the algorithm provides the 3-D map and the trajectory in real time; 4) accurate, because it has been validated with respect to ground-truth; and 5) robust to inter-patient variability, because it has performed successfully over the validation sequences.

  1. Comparative assessment of knee extensor and flexor muscle strength measured using a hand-held vs. isokinetic dynamometer. (United States)

    Muff, Guillaume; Dufour, Stéphane; Meyer, Alain; Severac, François; Favret, Fabrice; Geny, Bernard; Lecocq, Jehan; Isner-Horobeti, Marie-Eve


    [Purpose] To compare measurements of knee extensor and flexor muscle strength performed using a hand-held dynamometer and an isokinetic dynamometer in apparently healthy subjects. [Subjects and Methods] Thirty adult volunteers underwent knee muscle strength evaluation using an isokinetic or a hand-held dynamometer. [Results] Strong positive correlations were found between the 2 methods, with correlation coefficients r ranging from 0.72 (95% confidence interval [CI], 0.48-0.86) to 0.87 (95% CI, 0.75-0.94), depending on the muscle group and the isokinetic evaluation mode. The reproducibility of the hand-held dynamometer findings was good, judged by a coefficient of variation of 3.2-4.2%. However, the correlation between the 2 methods for the assessment of flexor/extensor ratios ranged from -0.04 to 0.46. [Conclusion] Knee extensor and flexor muscle strength recorded with a hand-held dynamometer is reproducible and significantly correlated with the isokinetic values, indicating that this method may in some cases be a useful replacement for isokinetic strength measurement. However, for strength ratio assessment, and when judged against the isokinetic standard, a hand-held dynamometer is not a valid option.

  2. Optimization of ATSC Mobile Handheld Service Capacity

    Directory of Open Access Journals (Sweden)

    Omneya Issa


    Full Text Available Mobile TV has become a reality offered on several mobile delivery systems. Among them is the Advanced Television System Committee (ATSC system for mobile and handheld digital television services, known as ATSC Mobile DTV or ATSC M/H, which has moved from standardization to implementation. As the North American broadcast industry is preparing to provide Mobile DTV service to consumers, this work discusses important technical parameters that affect the TV service quality and capacity. Since additional error correction mechanisms were added to overcome mobile transmission problems, the available payload for M/H services is limited. This creates a need to efficiently use the available M/H bandwidth. The paper aims to optimize the Mobile DTV service capacity while maintaining an acceptable perceived quality. It presents tradeoffs between several factors affecting service capacity and signal robustness, which is prominent for designing Mobile TV broadcasting scenarios.

  3. Handheld Multi-Gas Meters Assessment Report

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Gustavious [Brigham Young Univ., Provo, UT (United States); Wald-Hopkins, Mark David [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Obrey, Stephen J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Akhadov, Valida Dushdurova [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)


    Handheld multi-gas meters (MGMs) are equipped with sensors to monitor oxygen (O2) levels and additional sensors to detect the presence of combustible or toxic gases in the environment. This report is limited to operational response-type MGMs that include at least four different sensors. These sensors can vary by type and by the monitored chemical. In real time, the sensors report the concentration of monitored gases in the atmosphere near the MGM. In April 2016 the System Assessment and Validation for Emergency Responders (SAVER) Program conducted an operationally-oriented assessment of MGMs. Five MGMs were assessed by emergency responders. The criteria and scenarios used in this assessment were derived from the results of a focus group of emergency responders with experience in using MGMs. The assessment addressed 16 evaluation criteria in four SAVER categories: Usability, Capability, Maintainability, and Deployability.

  4. Optical links in handheld multimedia devices (United States)

    van Geffen, S.; Duis, J.; Miller, R.


    Ever emerging applications in handheld multimedia devices such as mobile phones, laptop computers, portable video games and digital cameras requiring increased screen resolutions are driving higher aggregate bitrates between host processor and display(s) enabling services such as mobile video conferencing, video on demand and TV broadcasting. Larger displays and smaller phones require complex mechanical 3D hinge configurations striving to combine maximum functionality with compact building volumes. Conventional galvanic interconnections such as Micro-Coax and FPC carrying parallel digital data between host processor and display module may produce Electromagnetic Interference (EMI) and bandwidth limitations caused by small cable size and tight cable bends. To reduce the number of signals through a hinge, the mobile phone industry, organized in the MIPI (Mobile Industry Processor Interface) alliance, is currently defining an electrical interface transmitting serialized digital data at speeds >1Gbps. This interface allows for electrical or optical interconnects. Above 1Gbps optical links may offer a cost effective alternative because of their flexibility, increased bandwidth and immunity to EMI. This paper describes the development of optical links for handheld communication devices. A cable assembly based on a special Plastic Optical Fiber (POF) selected for its mechanical durability is terminated with a small form factor molded lens assembly which interfaces between an 850nm VCSEL transmitter and a receiving device on the printed circuit board of the display module. A statistical approach based on a Lean Design For Six Sigma (LDFSS) roadmap for new product development tries to find an optimum link definition which will be robust and low cost meeting the power consumption requirements appropriate for battery operated systems.

  5. The transforming effect of handheld computers on nursing practice. (United States)

    Thompson, Brent W


    Handheld computers have the power to transform nursing care. The roots of this power are the shift to decentralization of communication, electronic health records, and nurses' greater need for information at the point of care. This article discusses the effects of handheld resources, calculators, databases, electronic health records, and communication devices on nursing practice. The US government has articulated the necessity of implementing the use of handheld computers in healthcare. Nurse administrators need to encourage and promote the diffusion of this technology, which can reduce costs and improve care.

  6. Handheld FRET-Aptamer Sensor for Water Safety Project (United States)

    National Aeronautics and Space Administration — Operational Technologies Corporation (OpTech) proposes to expand its current NASA Phase 2 SBIR handheld fluorometer and bone marker fluorescence resonance energy...

  7. Traffic monitoring using handheld GSM phones. Part A: Literature scan

    NARCIS (Netherlands)

    Lindveld, C.; Catalano, S.


    Rapport in opdracht van Syntrack (A joint venture between Ericsson and Libertel-Vodaphone). This report contains the findings of a literature scan concerning the use of handheld mobile phones in traffic monitoring.

  8. Traffic monitoring using handheld GSM phones. Part B: Simulation study

    NARCIS (Netherlands)

    Catalano, S.; Van der Zijpp, N.J.


    Revised version of LVV rapport, VK 2001.004. This report contains the description of a novel map-matching algorithm, and the results of a simulation study into the feasibility of traffic monitoring using handheld mobile phones.

  9. Reshaping the laboratory results presentation layer: three interfaces for handheld devices. (United States)

    Ehrler, Frederic; Brissaud, Marion; Wipfli, Rolf; Lovis, Christian


    The interpretation of laboratory results is a critical part of the clinical decision making process. The proper understanding of many clinical conditions depends on the identification of evidences in the laboratory reports. If the classic tabular presentation of laboratory results has demonstrated its efficiency since many years, the increase number of potential results, the increased complexity of cases and the time shortage to analyses cases raise the question of finding more efficient ways of displaying these results to clinicians. The presentation layer becomes even more crucial when it comes to small-sized interactive displays. In this work, we discuss three alternative graphical representations of laboratory results adapted to handheld devices.

  10. Introducing Handheld Computing for Interactive Medical Education

    Directory of Open Access Journals (Sweden)

    Joseph Finkelstein


    Full Text Available The goals of this project were: (1 development of an interactive multimedia medical education tool (CO-ED utilizing modern features of handheld computing (PDA and major constructs of adult learning theories, and (2 pilot testing of the computer-assisted education in residents and clinicians. Comparison of the knowledge scores using paired t-test demonstrated statistically significant increase in subject knowledge (p<0.01 after using CO-ED. Attitudinal surveys were analyzed by total score (TS calculation represented as a percentage of a maximal possible score. The mean TS was 74.5±7.1%. None of the subjects (N=10 had TS less than 65% and in half of the subjects (N=5 TS was higher than 75%. Analysis of the semi-structured in-depth interviews showed strong support of the study subjects in using PDA as an educational tool, and high acceptance of CO-ED user interface. We concluded that PDA have a significant potential as a tool for clinician education.

  11. An Adaptive Geometry Game for Handheld Devices

    Directory of Open Access Journals (Sweden)

    Harri Ketamo


    Full Text Available The development of adaptive learning systems is only in the very beginning. In fact, the concept of adaptive learning systems range from different user interfaces to behaviour adaptive systems as well as from the place and time independent systems to terminal independent systems. When approaching the concept of adaptive learning materials, we must first have conceptual models of the behaviour of different learners within digital environments.The aim of this study was to develop a geometry learning game that adapts to user’s behaviour. The learners in this study were six years old Finnish pre-school pupils. The adaptive system was very limited and the observed behaviour was defined as very simple. However, the software developed achieves good learning results among the tested pupils. The study shows that the learning effect is very promising with this kind of handheld platform and simple adaptation system. This study gives good visions of what can be achieved with more complex behaviour adaptive systems in the field of eLearning.

  12. Hand-held metal detector identification of ingested foreign bodies. (United States)

    Sacchetti, A; Carraccio, C; Lichenstein, R


    The study purpose was to determine the ability of hand-held metal detectors (HHMDs) to identify the presence of ingested metallic foreign bodies (MFBs). Twenty-three children presenting to the emergency department with a complaint of MFBs ingested were enrolled. Sixteen of 23 patients had radiographically proven foreign bodies. The MFBs comprised coins (n = 11), a button battery (n = 1), a medallion (n = 1), a token (n = 1), a needle (n = 1), and a marble (leaded glass) (n = 1). The HHMD correctly detected 15 of 16 radiographically positive MFBs (93%) and correctly excluded a potential MFB in six of six radiographically negative cases. The only foreign body not detected was an ingested needle. One radiograph was equivocal. Radiographic localization of the ingested objects was as follows: esophagus, n = 4; stomach, n = 9; and intestines, n = 3. The HHMD correctly localized all detected MFBs. The HHMD had a sensitivity of 94%, a specificity of 100%, a positive predictive value of 100%, and a negative predictive value of 86%. HHMDs are effective screening devices for possible ingested MFBs. Positive studies localized to the stomach and lower gastrointestinal tract do not require confirmatory radiographic studies.

  13. An analysis of sweep patterns for a handheld demining system (United States)

    Wilson, J. N.; Gader, P. D.; Ho, K. C.; Mazhar, R.


    Handheld sensors are commonly used to assist in landmine location and removal. A number of computer systems aimed at assisting humans in discriminating between buried mines and other objects have been developed. Each such system requires some protocol that involves sweeping the sensor over a region of ground using some set of patterns to search for objects (detection) and determine the nature of those objects (discrimination). The work reported here is an effort to determine an acceptable sweep pattern for mine/nonmine discrimination that provides good performance while still being simple for the operator to use. The paper describes a series of data collections and case studies employing a combined radar and metal detection sensor. The system was evaluated first using a robotic operator and later human operators. We discuss the application of a supervised learning system discriminator to each data set, and evaluate discrimination performance. We found that using a relatively simple sweep pattern, computer algorithms can achieve better discrimination performance than an expert human operator, and that (at least up to ten sweeps) our computer algorithm performs better with more sweeps over target.

  14. Potential role of a new hand-held miniature gamma camera in performing minimally invasive parathyroidectomy

    Energy Technology Data Exchange (ETDEWEB)

    Ortega, Joaquin; Lledo, Salvador [University of Valencia, Clinic University Hospital, Department of Surgery, Valencia (Spain); Ferrer-Rebolleda, Jose [Clinic University Hospital, Department of Nuclear Medicine, Valencia (Spain); Cassinello, Norberto [Clinic University Hospital, Unit of Endocrinologic and Bariatric Surgery, Valencia (Spain)


    Sestamibi scans have increased the use of minimally invasive parathyroidectomy (MIP) to treat primary hyperparathyroidism (PHPT) when caused by a parathyroid single adenoma. The greatest concern for surgeons remains the proper identification of pathological glands in a limited surgical field. We have studied the usefulness of a new hand-held miniature gamma camera (MGC) when used intraoperatively to locate parathyroid adenomas. To our knowledge this is the first report published on this subject in the scientific literature. Five patients with PHPT secondary to a single adenoma, positively diagnosed by preoperative sestamibi scans, underwent a MIP. A gamma probe for radioguided surgery and the new hand-held MGC were used consecutively to locate the pathological glands. This new MGC has a module composed of a high-resolution interchangeable collimator and a CsI(Na) scintillating crystal. It has dimensions of around 15 cm x 8 cm x 9 cm and weighs 1 kg. The intraoperative assay of PTH (ioPTH) was used to confirm the complete resection of pathological tissue. All cases were operated on successfully by a MIP. The ioPTH confirmed the excision of all pathological tissues. The MGC proved its usefulness in all patients, even in a difficult case in which the first attempt with the gamma probe failed. In all cases it offered real-time accurate intraoperative images. The hand-held MGC is a useful instrument in MIP for PHPT. It may be used to complement the standard tools used to date, or may even replace them, at least in selected cases of single adenomas. (orig.)

  15. A novel fully integrated handheld gamma camera

    Energy Technology Data Exchange (ETDEWEB)

    Massari, R.; Ucci, A.; Campisi, C. [Biostructure and Bioimaging Institute (IBB), National Research Council of Italy (CNR), Rome (Italy); Scopinaro, F. [University of Rome “La Sapienza”, S. Andrea Hospital, Rome (Italy); Soluri, A., E-mail: [Biostructure and Bioimaging Institute (IBB), National Research Council of Italy (CNR), Rome (Italy)


    In this paper, we present an innovative, fully integrated handheld gamma camera, namely designed to gather in the same device the gamma ray detector with the display and the embedded computing system. The low power consumption allows the prototype to be battery operated. To be useful in radioguided surgery, an intraoperative gamma camera must be very easy to handle since it must be moved to find a suitable view. Consequently, we have developed the first prototype of a fully integrated, compact and lightweight gamma camera for radiopharmaceuticals fast imaging. The device can operate without cables across the sterile field, so it may be easily used in the operating theater for radioguided surgery. The prototype proposed consists of a Silicon Photomultiplier (SiPM) array coupled with a proprietary scintillation structure based on CsI(Tl) crystals. To read the SiPM output signals, we have developed a very low power readout electronics and a dedicated analog to digital conversion system. One of the most critical aspects we faced designing the prototype was the low power consumption, which is mandatory to develop a battery operated device. We have applied this detection device in the lymphoscintigraphy technique (sentinel lymph node mapping) comparing the results obtained with those of a commercial gamma camera (Philips SKYLight). The results obtained confirm a rapid response of the device and an adequate spatial resolution for the use in the scintigraphic imaging. This work confirms the feasibility of a small gamma camera with an integrated display. This device is designed for radioguided surgery and small organ imaging, but it could be easily combined into surgical navigation systems.

  16. Handheld, point-of-care laser speckle imaging (United States)

    Farraro, Ryan; Fathi, Omid; Choi, Bernard


    Laser speckle imaging (LSI) enables measurement of relative changes in blood flow in biological tissues. We postulate that a point-of-care form factor will lower barriers to routine clinical use of LSI. Here, we describe a first-generation handheld LSI device based on a tablet computer. The coefficient of variation of speckle contrast was 0.05) between the measured speckle contrast values using either a handheld or mounted configuration. In vivo data collected during occlusion experiments demonstrate that a handheld LSI is capable of both quantitative and qualitative assessment of changes in blood flow. Finally, as a practical application of handheld LSI, we collected data from a 53-day-old neonate with confirmed compromised blood flow in the hand. We readily identified with LSI a region of diminished blood flow in the thumb of the affected hand. Our data collectively suggest that handheld LSI is a promising technique to enable clinicians to obtain point-of-care measurements of blood flow.

  17. 78 FR 27441 - NIJ Evaluation of Hand-Held Cell Phone Detector Devices (United States)


    ... of Justice Programs NIJ Evaluation of Hand-Held Cell Phone Detector Devices AGENCY: National...) is soliciting interest in supplying hand-held cell phone detector devices for participation in an... soliciting interest in supplying hand-held cell phone detector devices for participation in an evaluation...

  18. Examining the Potential of Handheld Computers: Findings from the Ohio PEP Project (United States)

    van 't Hooft, Mark; Diaz, Sebastian; Swan, Karen


    Handheld devices have the potential to make a large impact on K-12 educational settings, due to their relative low cost, high mobility, and interactive learning capabilities. This article, the outcome of a large-scale project examining the use of handheld computers, examines how handheld computers can improve teaching and learning, what…

  19. Comparative Evaluation of Handheld Robot-Aided Intraocular Laser Surgery (United States)

    Yang, Sungwook; MacLachlan, Robert A.; Martel, Joseph N.; Lobes, Louis A.; Riviere, Cameron N.


    This paper presents robot-aided intraocular laser surgery using a handheld robot known as Micron. The micromanipulator incorporated in Micron enables visual servoing of a laser probe, while maintaining a constant distance of the tool tip from the retinal surface. The comparative study was conducted with various control methods for evaluation of robot-aided intraocular laser surgery. PMID:27019653

  20. Diagnostic efficacy of handheld devices for emergency radiologic consultation.

    LENUS (Irish Health Repository)

    Toomey, Rachel J


    Orthopedic injury and intracranial hemorrhage are commonly encountered in emergency radiology, and accurate and timely diagnosis is important. The purpose of this study was to determine whether the diagnostic accuracy of handheld computing devices is comparable to that of monitors that might be used in emergency teleconsultation.

  1. Handheld technology acceptance in radiologic science education and training programs (United States)

    Powers, Kevin Jay

    The purpose of this study was to explore the behavioral intention of directors of educational programs in the radiologic sciences to adopt handheld devices to aid in managing student clinical data. Handheld devices were described to participants as a technology representing a class of mobile electronic devices including, but not limited to, personal digital assistants such as a Palm TX, Apple iPod Touch, Apple iPad or Hewlett Packard iPaq, and cellular or smartphones with third generation mobile capabilities such as an Apple iPhone, Blackberry or Android device. The study employed a non-experimental, cross-sectional survey design to determine the potential of adopting handheld technologies based on the constructs of Davis's (1989) Technology Acceptance Model. An online self-report questionnaire survey instrument was used to gather study data from 551 entry level radiologic science programs specializing in radiography, radiation therapy, nuclear medicine and medical sonography. The study design resulted in a single point in time assessment of the relationship between the primary constructs of the Technology Acceptance Model: perceived usefulness and perceived ease of use, and the behavioral intention of radiography program directors to adopt the information technology represented by hand held devices. Study results provide justification for investing resources to promote the adoption of mobile handheld devices in radiologic science programs and study findings serve as a foundation for further research involving technology adoption in the radiologic sciences.

  2. Traffic monitoring using handheld GSM phones. Part B: Simulation results

    NARCIS (Netherlands)

    Catalano, S.; Lindveld, C.; Van der Zijpp, N.


    Report published by the the University of Technology Delft, commissioned by Syntrack. This report contains the description of a novel map-matching algorithm, and the results of a simulation study into the feasibility of traffic monitoring using handheld mobile phones.

  3. Imaging Emission Spectra with Handheld and Cellphone Cameras (United States)

    Sitar, David


    As point-and-shoot digital camera technology advances it is becoming easier to image spectra in a laboratory setting on a shoestring budget and get immediate results. With this in mind, I wanted to test three cameras to see how their results would differ. Two undergraduate physics students and I used one handheld 7.1 megapixel (MP) digital Cannon…

  4. Web-Based Spatial Training Using Handheld Touch Screen Devices (United States)

    Martin-Dorta, Norena; Saorin, Jose Luis; Contero, Manuel


    This paper attempts to harness the opportunities for mobility and the new user interfaces that handheld touch screen devices offer, in a non-formal learning context, with a view to developing spatial ability. This research has addressed two objectives: first, analyzing the effects that training can have on spatial visualisation using the…

  5. Human Handheld-Device Interaction: An Adaptive User Interface

    NARCIS (Netherlands)

    Fitrianie, S.


    The move to smaller, lighter and more powerful (mobile) handheld devices, whe-ther PDAs or smart-phones, looks like a trend that is building up speed. With numerous embedded technologies and wireless connectivity, the drift opens up unlimited opportunities in daily activities that are both more effi

  6. Epilepsy Forewarning Using A Hand-Held Device

    Energy Technology Data Exchange (ETDEWEB)

    Hively, LM


    Over the last decade, ORNL has developed and patented a novel approach for forewarning of a large variety of machine and biomedical events. The present implementation uses desktop computers to analyze archival data. This report describes the next logical step in this effort, namely use of a hand-held device for the analysis.

  7. Neurosurgery contact handheld probe based on sapphire shaped crystal (United States)

    Shikunova, I. A.; Stryukov, D. O.; Rossolenko, S. N.; Kiselev, A. M.; Kurlov, V. N.


    A handheld contact probe based on sapphire shaped crystal is developed for intraoperative spectrally-resolved optical diagnostics, laser coagulation and aspiration of malignant brain tissue. The technology was integrated into the neurosurgical workflow for intraoperative real-time identification and removing of invasive brain cancer.

  8. Hand-Held Ultrasonic Instrument for Reading Matrix Symbols (United States)

    Schramm, Harry F.; Kula, John P.; Gurney, John W.; Lior, Ephraim D.


    A hand-held instrument that would include an ultrasonic camera has been proposed as an efficient means of reading matrix symbols. The proposed instrument could be operated without mechanical raster scanning. All electronic functions from excitation of ultrasonic pulses through final digital processing for decoding matrix symbols would be performed by dedicated circuitry within the single, compact instrument housing.

  9. Data for Users of Handheld Ion Mobility Spectrometers

    Energy Technology Data Exchange (ETDEWEB)

    Keith A. Daum; Sandra L. Fox


    Chemical detection technology end-user surveys conducted by Idaho National Laboratory (INL) in 2005 and 2007 indicated that first responders believed manufacturers’ claims for instruments sometimes were not supported in field applications, and instruments sometimes did not meet their actual needs. Based on these findings, the Department of Homeland Security (DHS) asked INL to conduct a similar survey for handheld ion mobility spectrometers (IMS), which are used by a broad community of first responders as well as for other applications. To better access this broad community, the INL used the Center for Technology Commercialization, Inc. (CTC), Public Safety Technology Center (PSTC) to set up an online framework to gather information from users of handheld IMS units. This framework (Survey Monkey) was then used to perform an online Internet survey, augmented by e-mail prompts, to get information from first responders and personnel from various agencies about their direct experience with handheld IMS units. Overall, 478 individuals responded to the survey. Of these, 174 respondents actually owned a handheld IMS. Performance and satisfaction data from these 174 respondents are captured in this report. The survey identified the following observations: • The most common IMS unit used by respondents was the Advanced Portable Detector (APD 2000), followed by ChemRae, Sabre 4000, Sabre 2000, Draeger Multi IMS, Chemical Agent Monitor-2, Chemical Agent Monitor, Vapor Tracer, and Vapor Tracer 2. • The primary owners were HazMat teams (20%), fire services (14%), local police (12%), and sheriffs’ departments (9%). • IMS units are seldom used as part of an integrated system for detecting and identifying chemicals but instead are used independently. • Respondents are generally confused about the capabilities of their IMS unit. This is probably a result of lack of training. • Respondents who had no training or fewer than 8 hours were not satisfied with the overall

  10. Quantitative Chemical Analysis of Archaeological Slag Material Using Handheld X-ray Fluorescence Spectrometry. (United States)

    Scott, Rebecca B; Eekelers, Kim; Degryse, Patrick


    Handheld X-ray fluorescence spectrometry (XRF) has seen a dramatic increase in use for archaeological projects. The attraction of the technique is its portable and nondestructive nature. In many cases, the archaeological artefacts in question cannot be destructively sampled, or the piece itself cannot be sent to an analytical laboratory. One of the current research interests associated with the Sagalassos project is the study of the Roman iron industry. Previously exported iron slag and ore from the site and the surrounding area was subjected to laboratory chemical analyses. These indicated that different ores were being utilized in the production of iron in different periods. In order to further the project the slag material still in the site depot needed to be analyzed. However, recent legislative changes mean that materials can only be analyzed on-site. Since samples could not be taken and destructive chemical analysis was no longer feasible, a portable, nondestructive technique was required. Handheld XRF can easily provide qualitative data, but these data are only comparable to other handheld XRF qualitative data, from the same device. Quantitative data gathering is possible, but can be more problematic, particularly when the material in question is heterogeneous in nature. A calibration file was created using the manufacturer's software and "in-house" standards made from the pre-quantified samples of iron slag available in the laboratory. In order to make the calibration as robust as possible, the composition of the standards was analyzed statistically to determine which of these created bias and leverage for specific elements. These standards were then omitted from the calibration for that element. The calibration was tested in the laboratory using samples of iron slag previously analyzed with wet chemistry, and the results indicated that most sample analyses showed 30% error were found in samples which contained very low or very high quantities of the

  11. RGB-D Hand-Held Ob ject Recognition Based on Heterogeneous Feature Fusion

    Institute of Scientific and Technical Information of China (English)

    吕雄; 蒋树强; 王双


    Ob ject recognition has many applications in human-machine interaction and multimedia retrieval. However, due to large intra-class variability and inter-class similarity, accurate recognition relying only on RGB data is still a big challenge. Recently, with the emergence of inexpensive RGB-D devices, this challenge can be better addressed by leveraging additional depth information. A very special yet important case of object recognition is hand-held object recognition, as manipulating objects with hands is common and intuitive in human-human and human-machine interactions. In this paper, we study this problem and introduce an effective framework to address it. This framework first detects and segments the hand-held ob ject by exploiting skeleton information combined with depth information. In the ob ject recognition stage, this work exploits heterogeneous features extracted from different modalities and fuses them to improve the recognition accuracy. In particular, we incorporate handcrafted and deep learned features and study several multi-step fusion variants. Experimental evaluations validate the effectiveness of the proposed method.

  12. Marker-Based Embodied Interaction for Handheld Augmented Reality Games

    Directory of Open Access Journals (Sweden)

    Michael Rohs


    Full Text Available This article deals with embodied user interfaces for handheld augmented reality games, which consist of both physical and virtual components. We have developed a number of spatial interaction techniques that optically capture the device’s movement and orientation relative to a visual marker. Such physical interactions in 3D space enable manipulative control of mobile games. In addition to acting as a physical controller that recognizes multiple game-dependent gestures, the mobile device augments the camera view with graphical overlays. We describe three game prototypes that use ubiquitous product packaging and other passive media as backgrounds for handheld augmentation. The prototypes can be realized on widely available off-the-shelf hardware and require only minimal setup and infrastructure support.

  13. Handheld Multi-Gas Meters Market Survey Report

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Gustavious [Brigham Young Univ., Provo, UT (United States); Wald-Hopkins, Mark David [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Obrey, Stephen J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Akhadov, Valida Dushdurova [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)


    Handheld multi-gas meters (MGMs) are equipped with sensors to monitor oxygen (O2) levels and additional sensors to detect the presence of combustible or toxic gases in the environment. This report is limited to operational response-type MGMs that include at least four different sensors. These sensors can vary by type and by the chemical monitored. In real time, the sensors report the concentration of monitored gases in the atmosphere near the MGM. To provide emergency responders with information on handheld multi-gas meters, the System Assessment and Validation for Emergency Responders (SAVER) Program conducted a market survey. This market survey report is based on information gathered between November 2015 and February 2016 from vendors, Internet research, industry publications, an emergency responder focus group, and a government issued Request for Information (RFI) that was posted on the Federal Business Opportunities website.

  14. A Standalone Markerless 3D Tracker for Handheld Augmented Reality

    CERN Document Server

    Lima, Joao Paulo; Kelner, Judith


    This paper presents an implementation of a markerless tracking technique targeted to the Windows Mobile Pocket PC platform. The primary aim of this work is to allow the development of standalone augmented reality applications for handheld devices based on natural feature tracking. In order to achieve this goal, a subset of two computer vision libraries was ported to the Pocket PC platform. They were also adapted to use fixed point math, with the purpose of improving the overall performance of the routines. The port of these libraries opens up the possibility of having other computer vision tasks being executed on mobile platforms. A model based tracking approach that relies on edge information was adopted. Since it does not require a high processing power, it is suitable for constrained devices such as handhelds. The OpenGL ES graphics library was used to perform computer vision tasks, taking advantage of existing graphics hardware acceleration. An augmented reality application was created using the implement...

  15. Real-time focal stack compositing for handheld mobile cameras (United States)

    Solh, Mashhour


    Extending the depth of field using a single lens camera on a mobile device can be achieved by capturing a set of images each focused at a different depth or focal stack then combine these samples of the focal stack to form a single all-in-focus image or an image refocused at a desired depth of field. Focal stack compositing in real time for a handheld mobile camera has many challenges including capturing, processing power, handshaking, rolling shutter artifacts, occlusion, and lens zoom effect. In this paper, we describe a system for a real time focal stack compositing system for handheld mobile device with an alignment and compositing algorithms. We will also show all-in-focus images captured and processed by a cell phone camera running on Android OS.

  16. Integrating RFID technique to design mobile handheld inventory management system (United States)

    Huang, Yo-Ping; Yen, Wei; Chen, Shih-Chung


    An RFID-based mobile handheld inventory management system is proposed in this paper. Differing from the manual inventory management method, the proposed system works on the personal digital assistant (PDA) with an RFID reader. The system identifies electronic tags on the properties and checks the property information in the back-end database server through a ubiquitous wireless network. The system also provides a set of functions to manage the back-end inventory database and assigns different levels of access privilege according to various user categories. In the back-end database server, to prevent improper or illegal accesses, the server not only stores the inventory database and user privilege information, but also keeps track of the user activities in the server including the login and logout time and location, the records of database accessing, and every modification of the tables. Some experimental results are presented to verify the applicability of the integrated RFID-based mobile handheld inventory management system.

  17. Applicability of a Diffuse Reflectance Infrared Fourier Transform handheld spectrometer to perform in situ analyses on Cultural Heritage materials. (United States)

    Arrizabalaga, Iker; Gómez-Laserna, Olivia; Aramendia, Julene; Arana, Gorka; Madariaga, Juan Manuel


    This work studies the applicability of a Diffuse Reflectance Infrared Fourier Transform handheld device to perform in situ analyses on Cultural Heritage assets. This portable diffuse reflectance spectrometer has been used to characterise and diagnose the conservation state of (a) building materials of the Guevara Palace (15th century, Segura, Basque Country, Spain) and (b) different 19th century wallpapers manufactured by the Santa Isabel factory (Vitoria-Gasteiz, Basque Country, Spain) and by the well known Dufour and Leroy manufacturers (Paris, France), all of them belonging to the Torre de los Varona Castle (Villanañe, Basque Country, Spain). In all cases, in situ measurements were carried out and also a few samples were collected and measured in the laboratory by diffuse reflectance spectroscopy (DRIFT) in order to validate the information obtained by the handheld instrument. In the analyses performed in situ, distortions in the diffuse reflectance spectra can be observed due to the presence of specular reflection, showing the inverted bands caused by the Reststrahlen effect, in particular on those IR bands with the highest absorption coefficients. This paper concludes that the results obtained in situ by a diffuse reflectance handheld device are comparable to those obtained with laboratory diffuse reflectance spectroscopy equipment and proposes a few guidelines to acquire good spectra in the field, minimising the influence caused by the specular reflection.

  18. RTP redirection using a handheld device with Minisip



    This report presents several different techniques for diverting RTP streams when using a handheld mobile device. This device is running a version of Minisip as the SIP user agent. An introduction to the SIP protocol is given to provide some background to the reader prior to focusing upon the main goal: redirecting RTP streams. A set of requirements are defined and an RTP media transfer mode is chosen based upon these requirements. The requirements are derived from a study of a Linux cellular ...

  19. Elemental analysis using a handheld X-Ray fluorescence spectrometer (United States)

    Groover, Krishangi D.; Izbicki, John


    The U.S. Geological Survey is collecting geologic samples from local stream channels, aquifer materials, and rock outcrops for studies of trace elements in the Mojave Desert, southern California. These samples are collected because geologic materials can release a variety of elements to the environment when exposed to water. The samples are to be analyzed with a handheld X-ray fluorescence (XRF) spectrometer to determine the concentrations of up to 27 elements, including chromium.

  20. Interactive topology optimization on hand-held devices

    DEFF Research Database (Denmark)

    Aage, Niels; Nobel-Jørgensen, Morten; Andreasen, Casper Schousboe


    This paper presents an interactive topology optimization application designed for hand-held devices running iOS or Android. The TopOpt app solves the 2D minimum compliance problem with interactive control of load and support positions as well as volume fraction. Thus, it is possible to change......OS devices from the Apple App Store, at Google Play for the Android platform, and a web-version can be run from

  1. Carbonaceous species emitted from handheld two-stroke engines (United States)

    Volckens, John; Olson, David A.; Hays, Michael D.

    Small, handheld two-stroke engines used for lawn and garden work (e.g., string trimmers, leaf blowers, etc.) can emit a variety of potentially toxic carbonaceous air pollutants. Yet, the emissions effluents from these machines go largely uncharacterized, constraining the proper development of human exposure estimates, emissions inventories, and climate and air quality models. This study samples and evaluates chemical pollutant emissions from the dynamometer testing of six small, handheld spark-ignition engines—model years 1998-2002. Four oil-gas blends were tested in each engine in duplicate. Emissions of carbon dioxide, carbon monoxide, and gas-phase hydrocarbons were predominant, and the PM emitted was organic matter primarily. An ANOVA model determined that engine type and control tier contributed significantly to emissions variations across all identified compound classes; whereas fuel blend was an insignificant variable accounting for engines were generally intermediate in magnitude compared with other gasoline-powered engines, numerous compounds traditionally viewed as motor vehicle markers are also present in small engine emissions in similar relative proportions. Given that small, handheld two-stroke engines used for lawn and garden work account for 5-10% of total US emissions of CO, CO 2, NO x, HC, and PM 2.5, source apportionment models and human exposure studies need to consider the effect of these small engines on ambient concentrations in air polluted environments.

  2. Detecting buried explosive hazards with handheld GPR and deep learning (United States)

    Besaw, Lance E.


    Buried explosive hazards (BEHs), including traditional landmines and homemade improvised explosives, have proven difficult to detect and defeat during and after conflicts around the world. Despite their various sizes, shapes and construction material, ground penetrating radar (GPR) is an excellent phenomenology for detecting BEHs due to its ability to sense localized differences in electromagnetic properties. Handheld GPR detectors are common equipment for detecting BEHs because of their flexibility (in part due to the human operator) and effectiveness in cluttered environments. With modern digital electronics and positioning systems, handheld GPR sensors can sense and map variation in electromagnetic properties while searching for BEHs. Additionally, large-scale computers have demonstrated an insatiable appetite for ingesting massive datasets and extracting meaningful relationships. This is no more evident than the maturation of deep learning artificial neural networks (ANNs) for image and speech recognition now commonplace in industry and academia. This confluence of sensing, computing and pattern recognition technologies offers great potential to develop automatic target recognition techniques to assist GPR operators searching for BEHs. In this work deep learning ANNs are used to detect BEHs and discriminate them from harmless clutter. We apply these techniques to a multi-antennae, handheld GPR with centimeter-accurate positioning system that was used to collect data over prepared lanes containing a wide range of BEHs. This work demonstrates that deep learning ANNs can automatically extract meaningful information from complex GPR signatures, complementing existing GPR anomaly detection and classification techniques.

  3. Promoting Physical Activity through Hand-Held Computer Technology (United States)

    King, Abby C.; Ahn, David K.; Oliveira, Brian M.; Atienza, Audie A.; Castro, Cynthia M.; Gardner, Christopher D.


    Background Efforts to achieve population-wide increases in walking and similar moderate-intensity physical activities potentially can be enhanced through relevant applications of state-of-the-art interactive communication technologies. Yet few systematic efforts to evaluate the efficacy of hand-held computers and similar devices for enhancing physical activity levels have occurred. The purpose of this first-generation study was to evaluate the efficacy of a hand-held computer (i.e., personal digital assistant [PDA]) for increasing moderate intensity or more vigorous (MOD+) physical activity levels over 8 weeks in mid-life and older adults relative to a standard information control arm. Design Randomized, controlled 8-week experiment. Data were collected in 2005 and analyzed in 2006-2007. Setting/Participants Community-based study of 37 healthy, initially underactive adults aged 50 years and older who were randomized and completed the 8-week study (intervention=19, control=18). Intervention Participants received an instructional session and a PDA programmed to monitor their physical activity levels twice per day and provide daily and weekly individualized feedback, goal setting, and support. Controls received standard, age-appropriate written physical activity educational materials. Main Outcome Measure Physical activity was assessed via the Community Healthy Activities Model Program for Seniors (CHAMPS) questionnaire at baseline and 8 weeks. Results Relative to controls, intervention participants reported significantly greater 8-week mean estimated caloric expenditure levels and minutes per week in MOD+ activity (p<0.04). Satisfaction with the PDA was reasonably high in this largely PDA-naive sample. Conclusions Results from this first-generation study indicate that hand-held computers may be effective tools for increasing initial physical activity levels among underactive adults. PMID:18201644

  4. Handheld portable real-time tracking and communications device

    Energy Technology Data Exchange (ETDEWEB)

    Wiseman, James M [Albuquerque, NM; Riblett, Jr., Loren E. (Edgewood, NM); Green, Karl L [Albuquerque, NM; Hunter, John A [Albuquerque, NM; Cook, III, Robert N. (Rio Rancho, NM); Stevens, James R [Arlington, VA


    Portable handheld real-time tracking and communications devices include; a controller module, communications module including global positioning and mesh network radio module, data transfer and storage module, and a user interface module enclosed in a water-resistant enclosure. Real-time tracking and communications devices can be used by protective force, security and first responder personnel to provide situational awareness allowing for enhance coordination and effectiveness in rapid response situations. Such devices communicate to other authorized devices via mobile ad-hoc wireless networks, and do not require fixed infrastructure for their operation.

  5. Adaptation of Predictive Models to PDA Hand-Held Devices

    Directory of Open Access Journals (Sweden)

    Lin, Edward J


    Full Text Available Prediction models using multiple logistic regression are appearing with increasing frequency in the medical literature. Problems associated with these models include the complexity of computations when applied in their pure form, and lack of availability at the bedside. Personal digital assistant (PDA hand-held devices equipped with spreadsheet software offer the clinician a readily available and easily applied means of applying predictive models at the bedside. The purposes of this article are to briefly review regression as a means of creating predictive models and to describe a method of choosing and adapting logistic regression models to emergency department (ED clinical practice.

  6. Development of Laser-Based Handheld Aerosol Particle Counter

    Institute of Scientific and Technical Information of China (English)

    CHEN Chang; LI Hui


    The JC-CA300 handheld Aerosol particle counter is designed and developed based on light scattering principle. The JC-CA300 counter is composed of optical sensor, DSP component and microprocessor unit. The hardware architecture is designed in compact style by SMT IC chips. The whole counter weight is less than 2 pounds. With 32K RAM space, the JC-CA300 can store 500 sampling records and support standard printer and communicate with a computer through RS232 interface. Based on experimental results, the main performance of JC-CA300 is better than that of the ARTI'S HHPC-6 instrument.

  7. Adaptive RF front-ends for hand-held applications

    CERN Document Server

    van Bezooijen, Andre; van Roermund, Arthur


    The RF front-end - antenna combination is a vital part of a mobile phone because its performance is very relevant to the link quality between hand-set and cellular network base-stations. The RF front-end performance suffers from changes in operating environment, like hand-effects, that are often unpredictable. ""Adaptive RF Front-Ends for Hand-Held Applications"" presents an analysis on the impact of fluctuating environmental parameters. In order to overcome undesired behavior two different adaptive control methods are treated that make RF frond-ends more resilient: adaptive impedance control,

  8. Developing a handheld record for patients with cystic fibrosis (United States)

    Narayan, Omendra; Davies, Siobhan; Tibbins, Carly; Rees, JH Martyn; Lenney, Warren; Gilchrist, Francis J


    Patient handheld records (PHHRs) promote self-management and empower the holder to take a more active role in the management of their disease. They have been used successfully in improving preventative care for children and have contributed to improved adherence in a number of chronic illnesses. Despite the potential advantages, there are no standard PHHRs for patients with cystic fibrosis (CF). We report the consultation process that led to the development of a CF PHHR, describe the final document, and analyze the feedback from their use at our center. We have made the CF PHHR freely available online. PMID:26316833

  9. Hand-held portable microarray reader for biodetection (United States)

    Thompson, Deanna Lynn; Coleman, Matthew A; Lane, Stephen M; Matthews, Dennis L; Albala, Joanna; Wachsmann-Hogiu, Sebastian


    A hand-held portable microarray reader for biodetection includes a microarray reader engineered to be small enough for portable applications. The invention includes a high-powered light-emitting diode that emits excitation light, an excitation filter positioned to receive the excitation light, a slide, a slide holder assembly for positioning the slide to receive the excitation light from the excitation filter, an emission filter positioned to receive the excitation light from the slide, a lens positioned to receive the excitation light from the emission filter, and a CCD camera positioned to receive the excitation light from the lens.

  10. An Investigation of Game-Embedded Handheld Devices to Enhance English Learning (United States)

    Hung, Hui-Chun; Young, Shelley Shwu-Ching


    This study proposed and implemented a system combining the advantages of both educational games and wireless handheld technology to promote the interactive English learning in the classroom setting. An interactive English vocabulary acquisition board game was designed with the system being implemented on handheld devices. Thirty sixth-grade…

  11. Students Using Handheld Computers to Learn Collaboratively in a First Grade Classroom (United States)

    Fritz, Megan Lynne


    This ethnographic study investigated how first grade students used handheld computers to learn in collaboration with others throughout the learning process. This research focused specifically on how the use of handheld computers impacts students' learning outcomes and relates to technology standards. A qualitative methodology was used to capture…

  12. The impact of legislation in Ireland on handheld mobile phone use by drivers.

    LENUS (Irish Health Repository)

    O'Meara, M


    Under the Road Traffic Act, 2006 handheld mobile phone use whilst driving is an offence liable to a fine and penalty points. The aim of this study was to determine whether there has been a change in driver behaviour following the introduction of this legislation. This study found that 2.3% of drivers were still using a handheld mobile phone.

  13. Micron: an Actively Stabilized Handheld Tool for Microsurgery (United States)

    MacLachlan, Robert A.; Becker, Brian C.; Tabarés, Jaime Cuevas; Podnar, Gregg W.; Lobes, Louis A.; Riviere, Cameron N.


    We describe the design and performance of a hand-held actively stabilized tool to increase accuracy in micro-surgery or other precision manipulation. It removes involuntary motion such as tremor by actuating the tip to counteract the effect of the undesired handle motion. The key components are a three-degree-of-freedom piezoelectric manipulator that has 400 μm range of motion, 1 N force capability, and bandwidth over 100 Hz, and an optical position measurement subsystem that acquires the tool pose with 4 μm resolution at 2000 samples/s. A control system using these components attenuates hand motion by at least 15 dB (a fivefold reduction). By considering the effect of the frequency response of Micron on the human visual feedback loop, we have developed a filter that reduces unintentional motion, yet preserves intuitive eye-hand coordination. We evaluated the effectiveness of Micron by measuring the accuracy of the human/machine system in three simple manipulation tasks. Handheld testing by three eye surgeons and three non-surgeons showed a reduction in position error of between 32% and 52%, depending on the error metric. PMID:23028266

  14. Handheld probes and galvanometer scanning for optical coherence tomography (United States)

    Duma, V.-F.; Dobre, G.; Demian, D.; Cernat, R.; Sinescu, C.; Topala, F. I.; Negrutiu, M. L.; Hutiu, Gh.; Bradu, A.; Rolland, J. P.; Podoleanu, A. G.


    As part of the ongoing effort of the biomedical imaging community to move Optical Coherence Tomography (OCT) systems from the lab to the clinical environment and produce OCT systems appropriate for multiple types of investigations in a medical department, handheld probes equipped with different types of scanners need to be developed. These allow different areas of a patient's body to be investigated using OCT with the same system and even without changing the patient's position. This paper reviews first the state of the art regarding OCT handheld probes. Novel probes with a uni-dimensional (1D) galvanometer-based scanner (GS) developed in our groups are presented. Their advantages and limitations are discussed. Aspects regarding the use of galvoscanners with regard to Micro-Electro- Mechanical Systems (MEMS) are pointed out, in relationship with our studies on optimal scanning functions of galvanometer devices in OCT. These scanning functions are briefly discussed with regard to their main parameters: profile, theoretical duty cycle, scan frequency, and scan amplitude. The optical design of the galvoscanner and refractive optics combination in the probe head, optimized for various applications, is considered. Perspectives of the field are pointed out in the final part of the paper.

  15. A Smartphone Controlled Handheld Microfluidic Liquid Handling System

    CERN Document Server

    Li, Baichen; Guan, Allan; Dong, Quan; Ruan, Kangcheng; Hu, Ronggui; Li, Zhenyu


    Microfluidics and lab-on-a-chip technologies have made it possible to manipulate small volume liquids with unprecedented resolution, automation and integration. However, most current microfluidic systems still rely on bulky off-chip infrastructures such as compressed pressure sources, syringe pumps and computers to achieve complex liquid manipulation functions. Here, we present a handheld automated microfluidic liquid handling system controlled by a smartphone, which is enabled by combining elastomeric on-chip valves and a compact pneumatic system. As a demonstration, we show that the system can automatically perform all the liquid handling steps of a bead-based sandwich immunoassay on a multi-layer PDMS chip without any human intervention. The footprint of the system is 6 by 10.5 by 16.5cm, and the total weight is 829g including battery. Powered by a 12.8V 1500mAh Li battery, the system consumed 2.2W on average during the immunoassay and lasted for 8.7 hrs. This handheld microfluidic liquid handling platform...

  16. Developing a handheld record for patients with cystic fibrosis

    Directory of Open Access Journals (Sweden)

    Narayan O


    Full Text Available Omendra Narayan,1 Siobhan Davies,1 Carly Tibbins,2 JH Martyn Rees,3 Warren Lenney,1,4 Francis J Gilchrist1,4 1Academic Department of Child Health, Royal Stoke University Hospital, Stoke-on-Trent, 2West Midlands Medicines for Children Research Network, Royal Stoke University Hospital, Stoke-on-Trent, 3Department of Paediatrics, Royal Shrewsbury Hospital, Shrewsbury, 4Institute for Science and Technology in Medicine, Keele University, Guy Hilton Research Centre, Stoke-on-Trent, UK Abstract: Patient handheld records (PHHRs promote self-management and empower the holder to take a more active role in the management of their disease. They have been used successfully in improving preventative care for children and have contributed to improved adherence in a number of chronic illnesses. Despite the potential advantages, there are no standard PHHRs for patients with cystic fibrosis (CF. We report the consultation process that led to the development of a CF PHHR, describe the final document, and analyze the feedback from their use at our center. We have made the CF PHHR freely available online.Keywords: cystic fibrosis, pediatrics, patient and public involvement, patient handheld records

  17. The use of handheld spectral domain optical coherence tomography in pediatric ophthalmology practice: Our experience of 975 infants and children

    Directory of Open Access Journals (Sweden)

    Ashwin Mallipatna


    Full Text Available Purpose: Optical coherence tomography (OCT is an important imaging tool assessing retinal architecture. In this article, we report a single centers experience of using handheld spectral domain (SD-OCT in a pediatric population using the Envisu 2300 (Bioptigen Inc., Research Triangle Park, NC, USA. Methods: We studied SD-OCT images from 975 patients imaged from January 2011 to December 2014. The variety of cases that underwent an SD-OCT was analyzed. Cases examples from different case scenarios were selected to showcase unique examples of many diseases. Results: Three hundred and sixty-eight infants (37.7% were imaged for retinopathy of prematurity, 362 children (37.1% underwent the test for evaluation of suboptimal vision or an unexplained vision loss, 126 children (12.9% for evaluation of nystagmus or night blindness, 54 children (5.5% for an intraocular tumor or a mass lesion such as retinoblastoma, and 65 children (6.7% for other diseases of the pediatric retina. The unique findings in the retinal morphology seen with some of these diseases are discussed. Conclusion: The handheld SD-OCT is useful in the evaluation of the pediatric retinal diseases. The test is useful in the assessment of vision development in premature children, evaluation of unexplained vision loss and amblyopia, nystagmus and night blindness, and intraocular tumors (including retinoblastoma.

  18. Spectra Transfer Between a Fourier Transform Near-Infrared Laboratory and a Miniaturized Handheld Near-Infrared Spectrometer. (United States)

    Hoffmann, Uwe; Pfeifer, Frank; Hsuing, Chang; Siesler, Heinz W


    The aim of this contribution is to demonstrate the transfer of spectra that have been measured on two different laboratory Fourier transform near-infrared (FT-NIR) spectrometers to the format of a handheld instrument by measuring only a few samples with both spectrometer types. Thus, despite the extreme differences in spectral range and resolution, spectral data sets that have been collected and quantitative as well as qualitative calibrations that have been developed thereof, respectively, over a long period on a laboratory instrument can be conveniently transferred to the handheld system. Thus, the necessity to prepare completely new calibration samples and the effort required to develop calibration models when changing hardware platforms is minimized. The enabling procedure is based on piecewise direct standardization (PDS) and will be described for the data sets of a quantitative and a qualitative application case study. For this purpose the spectra measured on the FT-NIR laboratory spectrometers were used as "master" data and transferred to the "target" format of the handheld instrument. The quantitative test study refers to transmission spectra of three-component liquid solvent mixtures whereas the qualitative application example encompasses diffuse reflection spectra of six different current polymers. To prove the performance of the transfer procedure for quantitative applications, partial least squares (PLS-1) calibrations were developed for the individual components of the solvent mixtures with spectra transferred from the master to the target instrument and the cross-validation parameters were compared with the corresponding parameters obtained for spectra measured on the master and target instruments, respectively. To test the retention of the discrimination ability of the transferred polymer spectra sets principal component analyses (PCAs) were applied exemplarily for three of the six investigated polymers and their identification was demonstrated by

  19. Texting while driving: is speech-based text entry less risky than handheld text entry? (United States)

    He, J; Chaparro, A; Nguyen, B; Burge, R J; Crandall, J; Chaparro, B; Ni, R; Cao, S


    Research indicates that using a cell phone to talk or text while maneuvering a vehicle impairs driving performance. However, few published studies directly compare the distracting effects of texting using a hands-free (i.e., speech-based interface) versus handheld cell phone, which is an important issue for legislation, automotive interface design and driving safety training. This study compared the effect of speech-based versus handheld text entries on simulated driving performance by asking participants to perform a car following task while controlling the duration of a secondary text-entry task. Results showed that both speech-based and handheld text entries impaired driving performance relative to the drive-only condition by causing more variation in speed and lane position. Handheld text entry also increased the brake response time and increased variation in headway distance. Text entry using a speech-based cell phone was less detrimental to driving performance than handheld text entry. Nevertheless, the speech-based text entry task still significantly impaired driving compared to the drive-only condition. These results suggest that speech-based text entry disrupts driving, but reduces the level of performance interference compared to text entry with a handheld device. In addition, the difference in the distraction effect caused by speech-based and handheld text entry is not simply due to the difference in task duration.

  20. Comparative Geometrical Investigations of Hand-Held Scanning Systems (United States)

    Kersten, T. P.; Przybilla, H.-J.; Lindstaedt, M.; Tschirschwitz, F.; Misgaiski-Hass, M.


    An increasing number of hand-held scanning systems by different manufacturers are becoming available on the market. However, their geometrical performance is little-known to many users. Therefore the Laboratory for Photogrammetry & Laser Scanning of the HafenCity University Hamburg has carried out geometrical accuracy tests with the following systems in co-operation with the Bochum University of Applied Sciences (Laboratory for Photogrammetry) as well as the Humboldt University in Berlin (Institute for Computer Science): DOTProduct DPI-7, Artec Spider, Mantis Vision F5 SR, Kinect v1 + v2, Structure Sensor and Google's Project Tango. In the framework of these comparative investigations geometrically stable reference bodies were used. The appropriate reference data were acquired by measurement with two structured light projection systems (AICON smartSCAN and GOM ATOS I 2M). The comprehensive test results of the different test scenarios are presented and critically discussed in this contribution.

  1. Handheld micromanipulator for robot-assisted stapes footplate surgery. (United States)

    Montes Grande, Gonzalo; Knisely, Anna J; Becker, Brian C; Yang, Sungwook; Hirsch, Barry E; Riviere, Cameron N


    Stapes footplate surgery is complex and delicate. This surgery is carried out in the middle ear to improve hearing. High accuracy is required to avoid critical tissues and structures near the surgical worksite. By suppressing the surgeon's tremor during the operation, accuracy can be improved. In this paper, a fully handheld active micromanipulator known as Micron is evaluated for its feasibility for this delicate operation. An ergonomic handle, a custom tip, and a brace attachment were designed for stapes footplate surgery and tested in a fenestration task through a fixed speculum. Accuracy was measured during simulated surgery in two different scenarios: Micron off (unaided) and Micron on (aided), both with image guidance. Preliminary results show that Micron significantly reduces the mean position error and the mean duration of time spent in specified dangerous zones.

  2. Radioactive uranium measurement in vivo using a handheld interfaced analyzer. (United States)

    Ly, Suw Young; Lee, Jin-Hui; Jung, Dong Ho


    A trace uranium (U) detection method was developed with a handheld voltammetric analyzer that was the size of a mobile phone, with working sensors made of simple graphite pencil electrode (PE). The optimum stripping voltammetric conditions were sought, and the following results were obtained: 0.0 to 0.08 ng/L working ranges and a statistically relative standard deviation of 1.78% (RSD; n=15) at a 10.0 microg/L U spike. The experiment accumulation time used was only 150 s. Under this condition, the diagnostic detection limit approached 0.007 ng/L. The method was applied to soil of a natural rock in a radioactive mineralogy site. Earthworms that resided at this site were assayed. The method was found to be applicable in biological diagnosis or in real-time in vivo survey.

  3. Handheld and low-cost digital holographic microscopy

    CERN Document Server

    Shiraki, Atsushi; Shimobaba, Tomoyoshi; Masuda, Nobuyuki; Ito, Tomoyoshi


    This study developed handheld and low-cost digital holographic microscopy (DHM) by adopting an in-line type hologram, a webcam, a high power RGB light emitting diode (LED), and a pinhole. It cost less than 20,000 yen (approximately 250 US dollars at 80 yen/dollar), and was approximately 120 mm x 80 mm x 55 mm in size. In addition, by adjusting the recording-distance of a hologram, the lateral resolution power at the most suitable distance was 17.5 um. Furthermore, this DHM was developed for use in open source libraries, and is therefore low-cost and can be easily developed by anyone. In this research, it is the feature to cut down cost and size and to improve the lateral resolution power further rather than existing reports. This DHM will be a useful application in fieldwork, education, and so forth.

  4. Watermark in the Digital Video Broadcasting Handheld Transmission Signal

    Institute of Scientific and Technical Information of China (English)

    HU Ling-na; JIANG Ling-ge; HE Chen; YANG Feng


    Transmitter identification (TxID) technique is used to diagnose the operation status of radio trans-mitters in DTV distributed transmission network. A new TxID method for digital video broadcasting-handheld (DVB-H) system is proposed. Watermark is embedded in the DVB-H signal to form the composite signal. Ac-cording to watermarking theory we demonstrate the required signal level for watermarking signal to achieve given bit error Probability under different circumstance. By selecting the reference pattern to generate watermarking signal, peak-to-average power ratio (PAPR) of the transmitted signal can be improved. Simulation results show that even in wireless situation the receiver can distinguish the watermarking signal with low embedding strength, and distortion to the host signal can also be ignored.

  5. Hand-Held Devices Detect Explosives and Chemical Agents (United States)


    Ion Applications Inc., of West Palm Beach, Florida, partnered with Ames Research Center through Small Business Innovation Research (SBIR) agreements to develop a miniature version ion mobility spectrometer (IMS). While NASA was interested in the instrument for detecting chemicals during exploration of distant planets, moons, and comets, the company has incorporated the technology into a commercial hand-held IMS device for use by the military and other public safety organizations. Capable of detecting and identifying molecules with part-per-billion sensitivity, the technology now provides soldiers with portable explosives and chemical warfare agent detection. The device is also being adapted for detecting drugs and is employed in industrial processes such as semiconductor manufacturing.

  6. Analysis of accuracy in pointing with redundant hand-held tools: a geometric approach to the uncontrolled manifold method. (United States)

    Campolo, Domenico; Widjaja, Ferdinan; Xu, Hong; Ang, Wei Tech; Burdet, Etienne


    This work introduces a coordinate-independent method to analyse movement variability of tasks performed with hand-held tools, such as a pen or a surgical scalpel. We extend the classical uncontrolled manifold (UCM) approach by exploiting the geometry of rigid body motions, used to describe tool configurations. In particular, we analyse variability during a static pointing task with a hand-held tool, where subjects are asked to keep the tool tip in steady contact with another object. In this case the tool is redundant with respect to the task, as subjects control position/orientation of the tool, i.e. 6 degrees-of-freedom (dof), to maintain the tool tip position (3dof) steady. To test the new method, subjects performed a pointing task with and without arm support. The additional dof introduced in the unsupported condition, injecting more variability into the system, represented a resource to minimise variability in the task space via coordinated motion. The results show that all of the seven subjects channeled more variability along directions not directly affecting the task (UCM), consistent with previous literature but now shown in a coordinate-independent way. Variability in the unsupported condition was only slightly larger at the endpoint but much larger in the UCM.

  7. Handheld Nonlinear Detection of Delamination and Intrusion Faults in Composites Project (United States)

    National Aeronautics and Space Administration — In Phase I of the SBIR program, LEEOAT Company will develop a hand-held high-resolution ultrasonic nonlinear imager for non-destructive inspection (NDI) of...

  8. Reusable Handheld Electrolytes and Lab Technology for Humans (rHEALTH Sensor) Project (United States)

    National Aeronautics and Space Administration — The goal of rHEALTH sensor is a universal handheld sensor that can provide rapid, low-cost complete blood count (CBC) with differential, electrolyte analysis, and...

  9. 75 FR 27504 - Substantial Product Hazard List: Hand-Held Hair Dryers (United States)


    ... substantial product hazard.'' B. The Product A hand-held hair dryer is a portable electrical appliance with a..., electrically energized wires across which a fan blows air. These dryers are typically used in bathrooms...

  10. Reusable Handheld Electrolytes and Lab Technology for Humans (rHEALTH Sensor) Project (United States)

    National Aeronautics and Space Administration — The goal of the rHEALTH sensor is to provide rapid, low-cost, handheld complete blood count (CBC), cell differential counts, electrolyte measurements, and other lab...

  11. 75 FR 448 - In the Matter of: Certain Authentication Systems, Including Software and Handheld Electronic... (United States)


    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION In the Matter of: Certain Authentication Systems, Including Software and Handheld Electronic Devices; Notice of Investigation AGENCY: U.S. International Trade Commission. ACTION: Institution...

  12. Handheld Longwave Infrared Camera Based on Highly-Sensitive Quantum Well Infrared Photodetectors Project (United States)

    National Aeronautics and Space Administration — We propose to develop a compact handheld longwave infrared camera based on quantum well infrared photodetector (QWIP) focal plane array (FPA) technology. Based on...

  13. Evaluation of Handheld Assays for the Detection of Ricin and Staphylococcal Enterotoxin B in Disinfected Waters (United States)


    Evaluation of Handheld Assays for the Detection of Ricin and Staphylococcal Enterotoxin B in DisinfectedWaters MaryMargaretWade,1 Tracey D. Biggs,1...Staphylococcal Enterotoxin B (SEB) in water. Performance of HHAs was evaluated in formulated tap water with and without chlorine, reverse osmosis water (RO) with...Handheld Assays For The Detection of Ricin And Staphylococcal Enterotoxin B In Disinfected Waters 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM

  14. Evidence for handheld electronic medical records in improving care: a systematic review


    Straus Sharon E; Wu Robert C


    Abstract Background Handheld electronic medical records are expected to improve physician performance and patient care. To confirm this, we performed a systematic review of the evidence assessing the effects of handheld electronic medical records on clinical care. Methods To conduct the systematic review, we searched MEDLINE, EMBASE, CINAHL, and the Cochrane library from 1966 through September 2005. We included randomized controlled trials that evaluated effects on practitioner performance or...

  15. Hand-held water fluoride analysis: An accessible caries prevention tool for dental professionals. (United States)

    Quock, Ryan L; Yank, Stephanie W; Chan, Jarvis T


    This study sought to compare the relative accuracy of a commercially available hand-held water fluoride analysis unit with a standard laboratory bench-top fluoride-specific electrode/millivoltmeter apparatus, with the goal of identifying possible practical applications of the hand-held unit for preventive dentistry. The units analyzed identical gravimetrically prepared fluoride solutions ranging from 0.1 to 4.0 ppm. The average difference between the measurements from the hand-held unit and the nominal values of the fluoride solutions was 0.011 ppm (SD = 0.068), and the average difference between the hand-held unit's measurements and the bench-top unit's measurements was 0.030 ppm (SD = 0.115). T-test analysis demonstrated no statistical difference between measurements from the hand-held unit with either the nominal values of the fluoride solutions or the bench-top unit's measurements. Results indicate that the hand-held water fluoride analysis unit has an appropriate level of accuracy for the measurement of fluoride levels in drinking water samples by dental professionals.

  16. Portable multiwavelength laser diode source for handheld photoacoustic devices (United States)

    Canal, Celine; Laugustin, Arnaud; Kohl, Andreas; Rabot, Olivier


    The ageing population faces today an increase of chronic diseases such as rheumatism/arthritis, cancer and cardio vascular diseases for which appropriate treatments based on a diagnosis at an early-stage of the disease are required. Some imaging techniques are already available in order to get structural information. Within the non-invasive group, ultrasound images are common in these fields of medicine. However, there is a need for a point-of-care device for imaging smaller structures such as blood vessels that cannot be observed with purely ultrasound based devices. Photoacoustics proved to be an attractive candidate. This novel imaging technique combines pulsed laser light for excitation of tissues and an ultrasound transducer as a receptor. Introduction of this technique into the clinic requires to drastically shrink the size and cost of the expensive and bulky nanosecond lasers generally used for light emission. In that context, demonstration of ultra-short pulse emission with highly efficient laser diodes in the near-infrared range has been performed by Quantel, France. A multi-wavelength laser source as small as a hand emitted more than 1 mJ per wavelength with four different wavelengths available in pulses of about 90 ns. Such a laser source can be integrated into high sensitivity photoacoustic handheld systems due to their outstanding electrical-to-optical efficiency of about 25 %. Further work continues to decrease the pulse length as low as 40 ns while increasing the pulse energy to 2 mJ.

  17. Cordless hand-held optical 3D sensor (United States)

    Munkelt, Christoph; Bräuer-Burchardt, Christian; Kühmstedt, Peter; Schmidt, Ingo; Notni, Gunther


    A new mobile optical 3D measurement system using phase correlation based fringe projection technique will be presented. The sensor consist of a digital projection unit and two cameras in a stereo arrangement, whereby both are battery powered. The data transfer to a base station will be done via WLAN. This gives the possibility to use the system in complicate, remote measurement situations, which are typical in archaeology and architecture. In the measurement procedure the sensor will be hand-held by the user, illuminating the object with a sequence of less than 10 fringe patterns, within a time below 200 ms. This short sequence duration was achieved by a new approach, which combines the epipolar constraint with robust phase correlation utilizing a pre-calibrated sensor head, containing two cameras and a digital fringe projector. Furthermore, the system can be utilized to acquire the all around shape of objects by using the phasogrammetric approach with virtual land marks introduced by the authors 1, 2. This way no matching procedures or markers are necessary for the registration of multiple views, which makes the system very flexible in accomplishing different measurement tasks. The realized measurement field is approx. 100 mm up to 400 mm in diameter. The mobile character makes the measurement system useful for a wide range of applications in arts, architecture, archaeology and criminology, which will be shown in the paper.

  18. Pulsed photoacoustic flow imaging with a handheld system. (United States)

    van den Berg, Pim J; Daoudi, Khalid; Steenbergen, Wiendelt


    Flow imaging is an important technique in a range of disease areas, but estimating low flow speeds, especially near the walls of blood vessels, remains challenging. Pulsed photoacoustic flow imaging can be an alternative since there is little signal contamination from background tissue with photoacoustic imaging. We propose flow imaging using a clinical photoacoustic system that is both handheld and portable. The system integrates a linear array with 7.5 MHz central frequency in combination with a high-repetition-rate diode laser to allow high-speed photoacoustic imaging--ideal for this application. This work shows the flow imaging performance of the system in vitro using microparticles. Both two-dimensional (2-D) flow images and quantitative flow velocities from 12 to 75  mm/s were obtained. In a transparent bulk medium, flow estimation showed standard errors of ∼7% the estimated speed; in the presence of tissue-realistic optical scattering, the error increased to 40% due to limited signal-to-noise ratio. In the future, photoacoustic flow imaging can potentially be performed in vivo using fluorophore-filled vesicles or with an improved setup on whole blood.

  19. Military forensic use of handheld 3D camera (United States)

    Larsson, Hâkan; Letalick, Dietmar


    One of the main threats for armed forces in conflict areas are attacks by improvised explosive devices (IED). After an IED attack a forensic investigation of the site is undertaken. In many ways military forensic work is similar to the civilian counterpart. There are the same needs to acquire evidence in the crime scene, such as fingerprints, DNA, and samples of the remains of the IED. Photos have to be taken and the geometry of the location shall be measured, preferably in 3D. A main difference between the military and the civilian forensic work is the time slot available for the scene investigation. The military must work under the threat of fire assault, e.g. snipers. The short time slot puts great demands on the forensic team and the equipment they use. We have done performance measurements of the Mantis-Vision F5 sensor and evaluated the usefulness in military forensic applications. This paper will describe some applications and show possibilities and also limitations of using a handheld laser imaging sensor for military forensic investigations.

  20. Handheld Raman Spectroscopy for the Distinction of Essential Oils Used in the Cosmetics Industry

    Directory of Open Access Journals (Sweden)

    Paul Vargas Jentzsch


    Full Text Available Essential oils are highly appreciated by the cosmetics industry because they have antimicrobial and antioxidant properties, among others. Since essential oils are natural products, their inclusion in cosmetic formulations is a common practice. Currently, low-quality and/or adulterated essential oils can be found on the market; therefore, analytical methods for control are required. Raman spectroscopy is a versatile technique that can be used for quality control tasks; the portability of modern devices expand the analytical possibilities also to in situ measurements. Fifteen essential oils of interest for the cosmetics industry were measured using a handheld Raman spectrometer, and the assignment of the main bands observed in their average spectra was proposed. In most cases, it is possible to distinguish the essential oils by a simple visual inspection of their characteristic Raman bands. However, for essential oils extracted from closely-related vegetable species and containing the same main component in a very high proportion, the visual inspection of the spectra may be not enough, and the application of chemometric methods is suggested. Characteristic Raman bands for each essential oil can be used to both identify the essential oils and detect adulterations.

  1. Detection of coins ingested by children using a handheld metal detector: a systematic review. (United States)

    Lee, J B; Ahmad, S; Gale, C P


    To determine if the use of a handheld metal detector (HHMD) can safely reduce the number of radiographs requested in cases of coins ingested by children, a search was performed to identify prospective studies of the ability of an HHMD to identify the presence or absence of ingested coin in children (17 years or younger). Outcome measures were presence or absence of coin on metal detector screening, and accuracy of coin localisation. Inclusion and exclusion criteria were defined. Mantel-Haenszel (fixed effect model) pooling with 95% confidence intervals (CI) was used to calculate overall sensitivities and specificities. In total, 11 studies met the inclusion criteria. The overall sensitivity of the HHMD at detecting the presence of coins was 99.4% (95% CI 98.0 to 99.9%) and accuracy at localisation was 99.8% (98.5 to 100.0%). The overall specificity of the HHMD was 100% (76.8 to 100%). Use of the HHMD is an accurate, radiation free, and cost effective method of identifying and localising coins ingested by children. An algorithm for investigating children with coin ingestion is proposed.

  2. Handheld Chem/Biosensor Using Extreme Conformational Changes in Designed Binding Proteins to Enhance Surface Plasmon Resonance (SPR) (United States)


    AFCEC-CX-TY-TR-2016-0007 HANDHELD CHEM/ BIOSENSOR USING EXTREME CONFORMATIONAL CHANGES IN DESIGNED BINDING PROTEINS TO ENHANCE SURFACE PLASMON...Include area code) 03/24/2016 Abstract 08/14/2015--03/31/2016 Handheld chem/ biosensor using extreme conformational changes in designed binding...Baltimore, Maryland on 17-21 April 2016. We propose the development of a highly sensitive handheld chem/ biosensor device using a novel class of engineered

  3. Portable Hand-Held Electrochemical Sensor for the Transuranics

    Energy Technology Data Exchange (ETDEWEB)

    Dale D. Russell, William B. Knowlton, Ph.D.; Russel Hertzog, Ph.D


    sensitive detector for uranium. Millimeter scale electrodes, operated by a hand-held instrument assembled in this lab and operated in the voltammetric mode, were transported to the DOE-Nevada test site (Las Vegas, NV) where field detection and quantitation of plutonium, uranium, and a mixture of these two elements was also demonstrated. Several probe designs were prepared, built and tested including probes with movable protective windows. A miniature, battery powered potentiostat was designed, built and demonstrated for use in a hand-held field portable instrument. This work was performed largely by undergraduates who gained valuable research experience, and many of them have continued on to graduate schools. In addition, they all gained exposure to and appreciation for national security research, in particular non-proliferation research. Four graduate students participated and one earned the MS degree on this project.

  4. Hand-Held Units for Short-Range Wireless Biotelemetry (United States)

    Miranda, Felix A.; Simons, Rainee N.


    Special-purpose hand-held radiotransceiver units have been proposed as means of short-range radio powering and interrogation of surgically implanted microelectromechanical sensors and actuators. These units are based partly on the same principles as those of the units described in "Printed Multi- Turn Loop Antennas for RF Biotelemetry" (LEW-17879-1), NASA Tech Briefs, Vol. 31, No. 6 (June 2007), page 48. Like the previously reported units, these units would make it unnecessary to have wire connections between the implanted devices and the external equipment used to activate and interrogate them. Like a unit of the previously reported type, a unit of the type now proposed would include a printed-circuit antenna on a dielectric substrate. The antenna circuitry would include integrated surface-mount inductors for impedance tuning. Circuits for processing the signals transmitted and received by the antenna would be included on the substrate. During operation, the unit would be positioned near (but not in electrical contact with) a human subject, in proximity to a microelectromechanical sensor or actuator that has been surgically implanted in the subject. It has been demonstrated that significant electromagnetic coupling with an implanted device could be established at a distance of as much as 4 in. (.10 cm). During operation in the interrogation mode, the antenna of the unit would receive a radio telemetry signal transmitted by the surgically implanted device. The antenna substrate would have dimensions of approximately 3.25 by 3.75 inches (approximately 8.3 by 9.5 cm). The substrate would have a thickness of the order of 30 mils (of the order of a somewhat less than a millimeter). The substrate would be made of low-radiofrequency- loss dielectric material that could be, for example, fused quartz, alumina, or any of a number of commercially available radio-frequency dielectric composite materials. The antenna conductors would typically be made of copper or a

  5. Direction-Sensitive Hand-Held Gamma-Ray Spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Mukhopadhyay, S.


    A novel, light-weight, hand-held gamma-ray detector with directional sensitivity is being designed. The detector uses a set of multiple rings around two cylindrical surfaces, which provides precise location of two interaction points on two concentric cylindrical planes, wherefrom the source location can be traced back by back projection and/or Compton imaging technique. The detectors are 2.0 × 2.0 mm europium-doped strontium iodide (SrI2:Eu2+) crystals, whose light output has been measured to exceed 120,000 photons/MeV, making it one of the brightest scintillators in existence. The crystal’s energy resolution, less than 3% at 662 keV, is also excellent, and the response is highly linear over a wide range of gamma-ray energies. The emission of SrI2:Eu2+ is well matched to both photo-multiplier tubes and blue-enhanced silicon photodiodes. The solid-state photomultipliers used in this design (each 2.0 × 2.0 mm) are arrays of active pixel sensors (avalanche photodiodes driven beyond their breakdown voltage in reverse bias); each pixel acts as a binary photon detector, and their summed output is an analog representation of the total photon energy, while the individual pixel accurately defines the point of interaction. A simple back-projection algorithm involving cone-surface mapping is being modeled. The back projection for an event cone is a conical surface defining the possible location of the source. The cone axis is the straight line passing through the first and second interaction points.

  6. A handheld point-of-care genomic diagnostic system.

    Directory of Open Access Journals (Sweden)

    Frank B Myers

    Full Text Available The rapid detection and identification of infectious disease pathogens is a critical need for healthcare in both developed and developing countries. As we gain more insight into the genomic basis of pathogen infectivity and drug resistance, point-of-care nucleic acid testing will likely become an important tool for global health. In this paper, we present an inexpensive, handheld, battery-powered instrument designed to enable pathogen genotyping in the developing world. Our Microfluidic Biomolecular Amplification Reader (µBAR represents the convergence of molecular biology, microfluidics, optics, and electronics technology. The µBAR is capable of carrying out isothermal nucleic acid amplification assays with real-time fluorescence readout at a fraction of the cost of conventional benchtop thermocyclers. Additionally, the µBAR features cell phone data connectivity and GPS sample geotagging which can enable epidemiological surveying and remote healthcare delivery. The µBAR controls assay temperature through an integrated resistive heater and monitors real-time fluorescence signals from 60 individual reaction chambers using LEDs and phototransistors. Assays are carried out on PDMS disposable microfluidic cartridges which require no external power for sample loading. We characterize the fluorescence detection limits, heater uniformity, and battery life of the instrument. As a proof-of-principle, we demonstrate the detection of the HIV-1 integrase gene with the µBAR using the Loop-Mediated Isothermal Amplification (LAMP assay. Although we focus on the detection of purified DNA here, LAMP has previously been demonstrated with a range of clinical samples, and our eventual goal is to develop a microfluidic device which includes on-chip sample preparation from raw samples. The µBAR is based entirely around open source hardware and software, and in the accompanying online supplement we present a full set of schematics, bill of materials, PCB layouts

  7. Investigation of the effects of operator technique on handheld sensor data for landmine detection (United States)

    Tantum, Stacy L.; Morton, Kenneth D., Jr.; Collins, Leslie M.; Torrione, Peter A.


    Ground penetrating radar (GPR) is a commonly employed sensing modality for landmine detection. It has been successfully deployed in vehicular systems, and is also being integrated into handheld systems. Handheld mine detection systems are typically deployed in situations where either the terrain or mission renders a vehicular-based system less effective. Handheld systems are often more compact and maneuverable, but quality of the sensor data may also be more dependent on the operators experience with and technique in using the system. In particular, the sensor height with respect to the air-ground interface may be more variable than with a vehicular-based system. This variation in sensor height above the air-ground interface may have the potential to adversely affect mine detection performance with the GPR sensing modality. In this work, the effects of operator technique on handheld sensor data quality is investigated, and ground alignment is explored as a potential approach to reducing variability in the sensor data quality due to operator technique. Results for data measured with a standard GPR/EMI handheld sensor at a standardized test site are presented.

  8. Consumer product safety: Risk assessment of exposure to asbestos emissions from hand-held hair dryers (United States)

    Hallenbeck, William H.


    The United States Consumer Product Safety Commission (CPSC) is concerned that consumer exposure to asbestos from consumer products may present an unreasonable risk of injury. Recently, CPSC has obtained agreement by industry to cease production and distribution of hair dryers containing asbestos heat insulation. CPSC intends to broaden its investigation by selecting consumer products containing asbestos for “priority attention.” The Commission does not intend to make quantitative estimates of cancer risks posed by exposure to asbestos fibers in making regulatory decisions. This position may lead to a serious waste of resources for the Commission, industry, and society. The Commission should focus its initial attention on those products for which the release of asbestos is significant enough to cause an unreasonable health risk. To make a risk assessment for a particular use of asbestos, CPSC must acquire or request data on asbestos emissions and define “unreasonable risk to health.” In an attempt to give some meaning to the phrase “risk assessment,” the primary goal of this paper is to present a detailed risk assessment of exposure to asbestos from hand-held hair dryers. Several scenarios of use are presented using various assumptions regarding time of operation, mixing of fibers in a small room, rate of fiber emission, and time of exposure. The worst case analysis of the health risk of exposure to hair dryer emissions is based on several conservative assumptions and shows that the increased number of deaths per year due to respiratory cancer is 4 for the entire United States population. A more representative case analysis shows the increased number of deaths to be on the order of 0.15 per year.

  9. Diagnosis of Opisthorchis viverrini Infection with Handheld Microscopy in Lao People's Democratic Republic. (United States)

    Bogoch, Isaac I; Sayasone, Somphou; Vonghachack, Youthanavanh; Meister, Isabel; Utzinger, Jürg; Odermatt, Peter; Andrews, Jason R; Keiser, Jennifer


    Opisthorchiasis is a neglected tropical disease, yet it is of considerable public health importance in Southeast Asia given the predilection for chronically infected persons to develop cholangiocarcinoma. We evaluated a handheld microscope for the diagnosis of Opisthorchis viverrini in a community-based setting in Lao People's Democratic Republic in comparison with conventional light microscopy. In stool samples collected from 104 individuals, handheld microscopy revealed a sensitivity of 70.6% and a specificity of 89.5% for O. viverrini infection. Pearson's correlation for quantitative fecal egg counts between the two devices was 0.98 (95% confidence interval: 0.98-0.99). With small adjustments to further increase diagnostic sensitivity, a handheld microscope may become a helpful tool to screen for O. viverrini and other helminth infections in public health settings.

  10. Soap opera video on handheld computers to reduce young urban women's HIV sex risk. (United States)

    Jones, Rachel


    The purpose of this study was to develop a soap opera video, A Story about Toni, Mike, and Valerie, designed to communicate HIV risk reduction themes. The study evaluated viewing the video and responding to audio computer assisted self-interview (ACASI) on a handheld computer. The sample was 76 predominately African American women, aged 18-29, in sexual relationships with men. Data were collected in urban neighborhoods in the northeastern United States. A pretest-posttest control group design with systematic assignment indicated statistically significant reduction in expectations to engage in unprotected sex in the experimental group. The handheld computer was found to be acceptable to view the near feature length video and complete ACASI. To date, no study has reported on use of video and ACASI on a handheld device to reduce HIV risk. The significance is the potential to stream health promotion videos to personal devices, such as cell phones.

  11. 78 FR 20695 - Walk-Through Metal Detectors and Hand-Held Metal Detectors Test Method Validation (United States)


    ... Office of Justice Programs Walk-Through Metal Detectors and Hand-Held Metal Detectors Test Method... detectors and hand-held metal detectors. In order to ensure that the test methods in the standards are... efforts from testing laboratories. NIJ is also seeking the participation of metal detector...

  12. Technology and the Prospective Teacher: Exploring the Use of the TI-83 Handheld Devices in Social Studies Education (United States)

    Crowe, Alicia; van 't Hooft, Mark


    Using technology to enhance student learning in social studies has become an important area for discussion and study within the field of social studies education. Handheld devices are one of the recently emerging technologies. This article describes an initial study of the TI-83 handheld device in the education of preservice social studies…

  13. Design of an Optical Character Recognition System for Camera-based Handheld Devices

    CERN Document Server

    Mollah, Ayatullah Faruk; Basu, Subhadip; Nasipuri, Mita


    This paper presents a complete Optical Character Recognition (OCR) system for camera captured image/graphics embedded textual documents for handheld devices. At first, text regions are extracted and skew corrected. Then, these regions are binarized and segmented into lines and characters. Characters are passed into the recognition module. Experimenting with a set of 100 business card images, captured by cell phone camera, we have achieved a maximum recognition accuracy of 92.74%. Compared to Tesseract, an open source desktop-based powerful OCR engine, present recognition accuracy is worth contributing. Moreover, the developed technique is computationally efficient and consumes low memory so as to be applicable on handheld devices.

  14. Dual-path handheld system for cornea and retina imaging using optical coherence tomography (United States)

    Shirazi, Muhammad Faizan; Wijesinghe, Ruchire Eranga; Ravichandran, Naresh Kumar; Kim, Pilun; Jeon, Mansik; Kim, Jeehyun


    A dual-path handheld system is proposed for cornea and retina imaging using spectral domain optical coherence tomography. The handheld sample arm is designed to acquire two images simultaneously. Both eyes of a person can be imaged at the same time to obtain the images of the cornea of one eye and the retina of the other eye. Cornea, retina, and optic disc images are acquired with the proposed sample arm. Experimental results demonstrate the usefulness of this system for imaging of different eye segments. This system reduces the time required for imaging of the two eyes and is cost effective.

  15. PubMed on Tap: discovering design principles for online information delivery to handheld computers. (United States)

    Hauser, Susan E; Demner-Fushman, Dina; Ford, Glenn; Thoma, George R


    Online access to biomedical information from handheld computers will be a valuable adjunct to other popular medical applications if information delivery systems are designed with handheld computers in mind. The goal of this project is to discover design principles to facilitate practitioners' access to online medical information at the point-of-care. A prototype system was developed to serve as a testbed for this research. Using the testbed, an initial evaluation has yielded several user interface design principles. Continued research is expected to discover additional user interface design principles as well as guidelines for results organization and system performance

  16. Application of Handheld Laser-Induced Breakdown Spectroscopy (LIBS) to Geochemical Analysis. (United States)

    Connors, Brendan; Somers, Andrew; Day, David


    While laser-induced breakdown spectroscopy (LIBS) has been in use for decades, only within the last two years has technology progressed to the point of enabling true handheld, self-contained instruments. Several instruments are now commercially available with a range of capabilities and features. In this paper, the SciAps Z-500 handheld LIBS instrument functionality and sub-systems are reviewed. Several assayed geochemical sample sets, including igneous rocks and soils, are investigated. Calibration data are presented for multiple elements of interest along with examples of elemental mapping in heterogeneous samples. Sample preparation and the data collection method from multiple locations and data analysis are discussed.

  17. Implementation of synthetic aperture imaging on a hand-held device

    DEFF Research Database (Denmark)

    Hemmsen, Martin Christian; Kjeldsen, Thomas; Larsen, Lee;


    This paper presents several implementations of Syn- thetic Aperture Sequential Beamforming (SASB) on commer- cially available hand-held devices. The implementations include real-time wireless reception of ultrasound radio frequency sig- nals and GPU processing for B-mode imaging. The proposed...... implementation demonstrates that SASB can be executed in-time for real-time ultrasound imaging. The wireless communication between probe and processing device satisfies the required bandwidth for real-time data transfer with current 802.11ac technology. The implementation is evaluated using four different hand-held...

  18. A Framework for Trusted Handheld Terminal Emulation%一种可信移动终端仿真架构

    Institute of Scientific and Technical Information of China (English)



    The evolution of mobile computing has led to the emergence of smart devices that is used in almost constant personal and business use, for example, accessing to email, social media, application stores, financial institutions, and other uses. Security has become a first order design consideration for handheld terminal and wireless communication systems. Researchers need to incorporate trusted computing mechanisms to secure and support these and other mobile use cases. Such security mechanisms include techniques to ensure device integrity, attestation, isolation and protected storage. The security issues of IT products are more important. This paper presents a framework for simulation trusted handheld terminal (THT) on the performance of applications in multi-core platform.%随着移动计算的不断发展,移动智能设备在个人和企业工作中得到了广泛应用.例如访问电子邮件、社交媒体、应用商店、金融机构以及其他用途.信息安全成为手持移动终端和无线通信系统设计首要考虑的问题.研究人员需要将可信计算的安全机制部署到这些移动应用中.可信安全机制包括:确保设备的完整性、认证、隔离和保护.在IT产品设计中信息安全问题已成为重要的问题.本文提出了一个框架,在多核计算机平台上模拟可信手持移动终端(THT)并对其进行性能分析.

  19. The Xsense project: The application of an intelligent sensor array for high sensitivity handheld explosives detectors

    DEFF Research Database (Denmark)

    Kostesha, Natalie; Schmidt, Michael Stenbæk; Bosco, Filippo


    Multiple independent sensors are used in security and military applications in order to increase sensitivity, selectivity and data reliability. The Xsense project has been initiated at the Technical University of Denmark in collaboration with a number of partners in an effort to produce a handheld...

  20. Wireless live streaming video of laparoscopic surgery: a bandwidth analysis for handheld computers. (United States)

    Gandsas, Alex; McIntire, Katherine; George, Ivan M; Witzke, Wayne; Hoskins, James D; Park, Adrian


    Over the last six years, streaming media has emerged as a powerful tool for delivering multimedia content over networks. Concurrently, wireless technology has evolved, freeing users from desktop boundaries and wired infrastructures. At the University of Kentucky Medical Center, we have integrated these technologies to develop a system that can wirelessly transmit live surgery from the operating room to a handheld computer. This study establishes the feasibility of using our system to view surgeries and describes the effect of bandwidth on image quality. A live laparoscopic ventral hernia repair was transmitted to a single handheld computer using five encoding speeds at a constant frame rate, and the quality of the resulting streaming images was evaluated. No video images were rendered when video data were encoded at 28.8 kilobytes per second (Kbps), the slowest encoding bitrate studied. The highest quality images were rendered at encoding speeds greater than or equal to 150 Kbps. Of note, a 15 second transmission delay was experienced using all four encoding schemes that rendered video images. We believe that the wireless transmission of streaming video to handheld computers has tremendous potential to enhance surgical education. For medical students and residents, the ability to view live surgeries, lectures, courses and seminars on handheld computers means a larger number of learning opportunities. In addition, we envision that wireless enabled devices may be used to telemonitor surgical procedures. However, bandwidth availability and streaming delay are major issues that must be addressed before wireless telementoring becomes a reality.

  1. Measurement of muscle strength with handheld dynamometer in Intensive Care Unit

    Directory of Open Access Journals (Sweden)

    Nidhi R Samosawala


    Full Text Available Background: Intensive Care Unit (ICU acquired weakness is a common complication in critically ill patients affecting their prognosis. The handheld dynamometry is an objective method in detecting minimum muscle strength change, which has an impact on the physical function of ICU survivors. The minimal change in the force can be measured in units of weight such as pounds or kilograms. Aim of the Study: To detect the changes in peripheral muscle strength with handheld dynamometer in the early stage of ICU stay and to observe the progression of muscle weakness. Methodology: Three upper and three lower limb muscles force measured with handheld dynamometer during ICU stay. Data were analyzed using repeated measures ANOVA to detect changes in force generated by muscle on alternate days of ICU stay. Results: There was a reduction in peripheral muscle strength from day 3 to day 5 as well from day 5 to day 7 of ICU stay (P < 0.01. The average reduction in peripheral muscle strength was 11.8% during ICU stay. Conclusion: This study showed a progressive reduction in peripheral muscle strength as measured by handheld dynamometer during early period of ICU stay.

  2. What Works Clearinghouse Quick Review: "Conceptualizing Astronomical Scale: Virtual Simulations on Handheld Tablet Computers Reverse Misconceptions" (United States)

    What Works Clearinghouse, 2014


    This study examined how using two different ways of displaying the solar system--a true-to-scale mode vs. an orrery mode--affected students' knowledge of astronomical concepts. Solar system displays were presented in a software application on a handheld tablet computer. In the true-to-scale mode, users navigated a simulated three-dimensional solar…

  3. Hand-held optical imager (Gen-2): improved instrumentation and target detectability. (United States)

    Gonzalez, Jean; Decerce, Joseph; Erickson, Sarah J; Martinez, Sergio L; Nunez, Annie; Roman, Manuela; Traub, Barbara; Flores, Cecilia A; Roberts, Seigbeh M; Hernandez, Estrella; Aguirre, Wenceslao; Kiszonas, Richard; Godavarty, Anuradha


    Hand-held optical imagers are developed by various researchers towards reflectance-based spectroscopic imaging of breast cancer. Recently, a Gen-1 handheld optical imager was developed with capabilities to perform two-dimensional (2-D) spectroscopic as well as three-dimensional (3-D) tomographic imaging studies. However, the imager was bulky with poor surface contact (~30%) along curved tissues, and limited sensitivity to detect targets consistently. Herein, a Gen-2 hand-held optical imager that overcame the above limitations of the Gen-1 imager has been developed and the instrumentation described. The Gen-2 hand-held imager is less bulky, portable, and has improved surface contact (~86%) on curved tissues. Additionally, the forked probe head design is capable of simultaneous bilateral reflectance imaging of both breast tissues, and also transillumination imaging of a single breast tissue. Experimental studies were performed on tissue phantoms to demonstrate the improved sensitivity in detecting targets using the Gen-2 imager. The improved instrumentation of the Gen-2 imager allowed detection of targets independent of their location with respect to the illumination points, unlike in Gen-1 imager. The developed imager has potential for future clinical breast imaging with enhanced sensitivity, via both reflectance and transillumination imaging.

  4. Hand-Held Model of a Sarcomere to Illustrate the Sliding Filament Mechanism in Muscle Contraction (United States)

    Jittivadhna, Karnyupha; Ruenwongsa, Pintip; Panijpan, Bhinyo


    From our teaching of the contractile unit of the striated muscle, we have found limitations in using textbook illustrations of sarcomere structure and its related dynamic molecular physiological details. A hand-held model of a striated muscle sarcomere made from common items has thus been made by us to enhance students' understanding of the…

  5. Handheld multispectral dual-axis confocal microscope for cervical cancer screening (United States)

    Sarapukdee, Pongsak; Rattanavarin, Santi; Jarujareet, Ungkarn; Khemthongcharoen, Numfon; Jolivot, Romuald; Jung, Il Woong; López, Daniel; Mandella, Michael J.; Piyawattanametha, Wibool


    Our work demonstrates a MEMS based handheld dual-axis confocal microscope for cervical cancer screening. Imaging demonstration is performed with plant and animal tissue biopsies. The data is collected and displayed in real time with 2-5 Hz frame rates.

  6. A Fresh Look at the Crystal Violet Lab with Handheld Camera Colorimetry (United States)

    Knutson, Theodore R.; Knutson, Cassandra M.; Mozzetti, Abbie R.; Campos, Antonio R.; Haynes, Christy L.; Penn, R. Lee


    Chemical kinetic experiments to determine rate laws are common in high school and college chemistry courses. For reactions involving a color change, rate laws can be determined experimentally using spectrophotometric or colorimetric equipment though this equipment can be cost prohibitive. Previous work demonstrated that inexpensive handheld camera…

  7. Phantom study quantifying the depth performance of a handheld magnetometer for sentinel lymph node biopsy

    NARCIS (Netherlands)

    Pouw, Joost J.; Bastiaan, Daniel M.C.; Klaase, Joost M.; Haken, ten Bennie


    Purpose The use of a magnetic nanoparticle tracer and handheld magnetometer for sentinel lymph node biopsy (SLNB) was recently introduced to overcome drawbacks associated with the use of radioisotope tracers. Unlike the gamma probe, the used magnetometers are not only sensitive to the tracer, but a

  8. A Mobile Mixed-Reality Environment for Children's Storytelling Using a Handheld Projector and a Robot (United States)

    Sugimoto, Masanori


    This paper describes a system called GENTORO that uses a robot and a handheld projector for supporting children's storytelling activities. GENTORO differs from many existing systems in that children can make a robot play their own story in a physical space augmented by mixed-reality technologies. Pilot studies have been conducted to clarify the…

  9. A Study of the Use of a Handheld Computer Algebra System in Discrete Mathematics (United States)

    Powers, Robert A.; Allison, Dean E.; Grassl, Richard M.


    This study investigated the impact of the TI-92 handheld Computer Algebra System (CAS) on student achievement in a discrete mathematics course. Specifically, the researchers examined the differences between a CAS section and a control section of discrete mathematics on students' in-class examinations. Additionally, they analysed student approaches…

  10. Detection of fecal contamination on beef meat surfaces using handheld fluorescence imaging device (HFID) (United States)

    Current meat inspection in slaughter plants, for food safety and quality attributes including potential fecal contamination, is conducted through by visual examination human inspectors. A handheld fluorescence-based imaging device (HFID) was developed to be an assistive tool for human inspectors by ...

  11. Left ventricular hypertrophy screening using a hand-held ultrasound device

    NARCIS (Netherlands)

    E.C. Vourvouri (Eleni); D. Poldermans (Don); A.F.L. Schinkel (Arend); L.Y. Koroleva; F. Sozzi (Fabiola); G.E. Parharidis; J.J. Bax (Jeroen); J.R.T.C. Roelandt (Jos)


    textabstractAIMS: To test the diagnostic potential of a hand-held ultrasound device for screening for left ventricular hypertrophy in a hypertensive population using a standard echocardiographic system as a reference. METHODS: One hundred consecutive hypertensive patients were enro

  12. Clinical assessment of hip strength using a hand-held dynamometer is reliable

    DEFF Research Database (Denmark)

    Thorborg, K; Petersen, J; Magnusson, S P;


    rotation (ER), internal rotation (IR), flexion (FLEX) and extension (EXT) using a hand-held dynamometer. Nine subjects (five males, four females), physically active for at least 2.5 h a week, were included. Twelve standardized isometric strength tests were performed twice with a 1-week interval in between...

  13. Online Responses towards Parental Rearing Styles Regarding Hand-Held Devices (United States)

    Geng, Gretchen; Disney, Leigh


    This article reviewed the literature on parental rearing styles and used responses from an online discussion forum to investigate people's opinions towards parental rearing styles and strategies when children use hand-held devices. Critical discourse analysis (CDA) was used as an analysis method via micro, meso and macro multi-level…

  14. Development of Real-Time Dual-Display Handheld and Bench-Top Hybrid-Mode SD-OCTs

    Directory of Open Access Journals (Sweden)

    Nam Hyun Cho


    Full Text Available Development of a dual-display handheld optical coherence tomography (OCT system for retina and optic-nerve-head diagnosis beyond the volunteer motion constraints is reported. The developed system is portable and easily movable, containing the compact portable OCT system that includes the handheld probe and computer. Eye posterior chambers were diagnosed using the handheld probe, and the probe could be fixed to the bench-top cradle depending on the volunteers’ physical condition. The images obtained using this handheld probe were displayed in real time on the computer monitor and on a small secondary built-in monitor; the displayed images were saved using the handheld probe’s built-in button. Large-scale signal-processing procedures such as k-domain linearization, fast Fourier transform (FFT, and log-scaling signal processing can be rapidly applied using graphics-processing-unit (GPU accelerated processing rather than central-processing-unit (CPU processing. The Labview-based system resolution is 1,024 × 512 pixels, and the frame rate is 56 frames/s, useful for real-time display. The 3D images of the posterior chambers including the retina, optic-nerve head, blood vessels, and optic nerve were composed using real-time displayed images with 500 × 500 × 500 pixel resolution. A handheld and bench-top hybrid mode with a dual-display handheld OCT was developed to overcome the drawbacks of the conventional method.

  15. Hand-held probe based optical imaging system towards breast cancer diagnosis (United States)

    Ge, Jiajia; Jayachandran, Bhavani; Regalado, Steven; Zhu, Banghe; Godavarty, Anuradha


    Near-infrared (NIR) optical imaging is an emerging noninvasive modality for breast cancer diagnosis. However, the currently available optical imaging systems towards tomography studies are limited either by instrument portability, patient comfort, or flexibility to image any given tissue volume. Herein, a hand-held based optical imaging system is developed such that it can possibly overcome some of the above limitations. The unique features of the hand-held optical probe are: (i) to perform simultaneous multiple point illumination and detection, thus decreasing the total imaging time and improving the overall signal strength; (ii) to adapt to the contour of tissue surface, thus decreasing the leakage of excitation and emission signal at contact surface; and (iii) to obtain trans-illumination measurements apart from reflectance measurements, thus improving the depth information. The increased detected signal strength as well as total interrogated tissue volume is demonstrated by simulation studies (i.e. forward model) over a 5×10×10 cc slab phantom. The appropriate number and layout of the source and detection points on the probe head is determined and the hand-held optical probe is developed. A frequency-domain ICCD (intensified charge coupled device) detection system, which allows simultaneous multiple points detection, is developed and coupled to the hand-held probe in order to perform fluorescence-enhanced optical imaging of tissue phantoms. In the future, imaging of homogenous liquid phantoms will be used for the assessment of this hand-held system, followed by extensive imaging studies on different phantoms types under various experimental conditions.

  16. Monitoring of WEEE plastics in regards to brominated flame retardants using handheld XRF

    Energy Technology Data Exchange (ETDEWEB)

    Aldrian, Alexia, E-mail: [Chair of Waste Processing Technology and Waste Management, Montanuniversitaet Leoben, Franz-Josef-Straße 18, 8700 Leoben (Austria); Ledersteger, Alfred, E-mail: [Saubermacher Dienstleistungs AG, Hans-Roth-Straße 1, 8073 Feldkirchen bei Graz (Austria); Pomberger, Roland, E-mail: [Chair of Waste Processing Technology and Waste Management, Montanuniversitaet Leoben, Franz-Josef-Straße 18, 8700 Leoben (Austria)


    Highlights: • Specification of an empirical factor for conversion from bromine to PBB and PBDE. • The handheld XRF device was validated for this particular application. • A very large number of over 4600 pieces of monitor housings was analysed. • The recyclable fraction mounts up to 85% for TV but only 53% of PC waste plastics. • A high percentage of pieces with bromine contents of over 50,000 ppm was obtained. - Abstract: This contribution is focused on the on-site determination of the bromine content in waste electrical and electronic equipment (WEEE), in particular waste plastics from television sets (TV) and personal computer monitors (PC) using a handheld X-ray fluorescence (XRF) device. The described approach allows the examination of samples in regards to the compliance with legal specifications for polybrominated biphenyls (PBBs) and polybrominated diphenyl ethers (PBDEs) directly after disassembling and facilitates the sorting out of plastics with high contents of brominated flame retardants (BFRs). In all, over 3000 pieces of black (TV) and 1600 pieces of grey (PC) plastic waste were analysed with handheld XRF technique for this study. Especially noticeable was the high percentage of pieces with a bromine content of over 50,000 ppm for TV (7%) and PC (39%) waste plastics. The applied method was validated by comparing the data of handheld XRF with results obtained by GC–MS. The results showed the expected and sufficiently accurate correlation between these two methods. It is shown that handheld XRF technique is an effective tool for fast monitoring of large volumes of WEEE plastics in regards to BFRs for on-site measurements.

  17. Handheld computers for self-administered sensitive data collection: A comparative study in Peru

    Directory of Open Access Journals (Sweden)

    Hughes James P


    Full Text Available Abstract Background Low-cost handheld computers (PDA potentially represent an efficient tool for collecting sensitive data in surveys. The goal of this study is to evaluate the quality of sexual behavior data collected with handheld computers in comparison with paper-based questionnaires. Methods A PDA-based program for data collection was developed using Open-Source tools. In two cross-sectional studies, we compared data concerning sexual behavior collected with paper forms to data collected with PDA-based forms in Ancon (Lima. Results The first study enrolled 200 participants (18–29 years. General agreement between data collected with paper format and handheld computers was 86%. Categorical variables agreement was between 70.5% and 98.5% (Kappa: 0.43–0.86 while numeric variables agreement was between 57.1% and 79.8% (Spearman: 0.76–0.95. Agreement and correlation were higher in those who had completed at least high school than those with less education. The second study enrolled 198 participants. Rates of responses to sensitive questions were similar between both kinds of questionnaires. However, the number of inconsistencies (p = 0.0001 and missing values (p = 0.001 were significantly higher in paper questionnaires. Conclusion This study showed the value of the use of handheld computers for collecting sensitive data, since a high level of agreement between paper and PDA responses was reached. In addition, a lower number of inconsistencies and missing values were found with the PDA-based system. This study has demonstrated that it is feasible to develop a low-cost application for handheld computers, and that PDAs are feasible alternatives for collecting field data in a developing country.

  18. Impacts of the SCA Core Framework on High Speed Broadband Waveform in SDR Handheld System (United States)

    Oh, Sangchul; Park, Namhoon; Kwon, Ohjun; Kim, Yeongjin

    In this paper, we have shown a major element occupying the large portion of software communications architecture (SCA)-based software defined radio (SDR) handheld embedded system and an important feature for implementing a high speed broadband radio to an SCA waveform through a couple of experiments. First, this paper identifies the main items possessing the large portion of SCA-based SDR handheld embedded system by the experiment on the target platform which is similar to a commercial mobile handheld system. Both the world interoperabillity for microwave access (WiMAX) and high speed downlink packet access (HSDPA) waveform software packages are used as an SCA waveform application. This paper also presents the results of the relative binary size distribution of SCA software resources for looking for the major elements making an SCA-based SDR handheld embedded system heavier. As a result, when focusing on the relative weight portion of SCA core framework (CF), the SCA CF takes 16% up and others have 84% out of the whole binary size distribution of SCA software resources. The results of the experiment give us notice that the weight portion of SCA CF is minor and compatible with the overall software binary size needs of an SCA-based SDR handheld embedded system, on the other hand, the practical problem on the lightweight is in a common object request broker architecture (CORBA) and extensible markup language (XML) parser resources. Second, this paper describes an important feature for implementing a high speed broadband radio to an SCA waveform and presents the performance evaluation results of the SCA port communication on both power PC (PPC) 405 and x86 processor platforms. The PPC 405 platform, which is similar to a commercial mobile handset, takes the value of average round trip time (RTT) with a maximum of thirty six millisecond. The x86 platform, however, which is analogous to a server platform, maintains stable micro-second resolution. From our experiments, we

  19. Mad City Mystery: Developing Scientific Argumentation Skills with a Place-based Augmented Reality Game on Handheld Computers (United States)

    Squire, Kurt D.; Jan, Mingfong


    While the knowledge economy has reshaped the world, schools lag behind in producing appropriate learning for this social change. Science education needs to prepare students for a future world in which multiple representations are the norm and adults are required to "think like scientists." Location-based augmented reality games offer an opportunity to create a "post-progressive" pedagogy in which students are not only immersed in authentic scientific inquiry, but also required to perform in adult scientific discourses. This cross-case comparison as a component of a design-based research study investigates three cases (roughly 28 students total) where an Augmented Reality curriculum, Mad City Mystery, was used to support learning in environmental science. We investigate whether augmented reality games on handhelds can be used to engage students in scientific thinking (particularly argumentation), how game structures affect students' thinking, the impact of role playing on learning, and the role of the physical environment in shaping learning. We argue that such games hold potential for engaging students in meaningful scientific argumentation. Through game play, players are required to develop narrative accounts of scientific phenomena, a process that requires them to develop and argue scientific explanations. We argue that specific game features scaffold this thinking process, creating supports for student thinking non-existent in most inquiry-based learning environments.

  20. A Study on Digital Video Broadcasting to a Handheld Device (DVB-H), Operating in UHF Band

    CERN Document Server

    Masood, Farhat


    In this paper, we will understand that the development of the Digital Video Broadcasting to a Handheld (DVB-H) standard makes it possible to deliver live broadcast television to a mobile handheld device. Building upon the strengths of the Digital Video Broadcasting - Terrestrial (DVB-T) standard in use in millions of homes, DVB-H recognizes the trend towards the personal consumption of media.

  1. Evaluating medical students’ proficiency with a handheld ophthalmoscope: a pilot study

    Directory of Open Access Journals (Sweden)

    Gilmour G


    Full Text Available Gregory Gilmour,1 James McKivigan2 1Physical Medicine and Rehabilitation, Michigan State University, Lansing, MI, 2School of Physical Therapy, Touro University, Henderson, NV, USA Introduction: Historically, testing medical students’ skills using a handheld ophthalmoscope has been difficult to do objectively. Many programs train students using plastic models of the eye which are a very limited fidelity simulator of a real human eye. This makes it difficult to be sure that actual proficiency is attained given the differences between the various models and actual patients. The purpose of this article is to introduce a method of testing where a medical student must match a patient with his/her fundus photo, ensuring objective evaluation as well as developing skills on real patients which are more likely to transfer into clinical practice directly. Presentation of case: Fundus photos from standardized patients (SPs were obtained using a retinal camera and placed into a grid using proprietary software. Medical students were then asked to examine a SP and attempt to match the patient to his/her fundus photo in the grid. Results: Of the 33 medical students tested, only 10 were able to match the SP’s eye to the correct photo in the grid. The average time to correct selection was 175 seconds, and the successful students rated their confidence level at 27.5% (average. The incorrect selection took less time, averaging 118 seconds, yet yielded a higher student-reported confidence level at 34.8% (average. The only noteworthy predictor of success (p<0.05 was the student’s age (p=0.02. Conclusion: It may be determined that there is an apparent gap in the ophthalmoscopy training of the students tested. It may also be of concern that students who selected the incorrect photo were more confident in their selections than students who chose the correct photo. More training may be necessary to close this gap, and future studies should attempt to establish

  2. Facile residue analysis of recent and prehistoric cook-stones using handheld Raman spectrometry

    CERN Document Server

    Short, Laura; Cao, Bin; Sinyukov, Alexander M; Joshi, Amitabh; Scully, Rob; Sanders, Virgil; Voronine, Dmitri V


    We performed food residue analysis of cook-stones from experimental and prehistoric earth ovens using a handheld Raman spectrometry. Progress in modern optical technology provides a facile means of rapid non-destructive identification of residue artifacts from archaeological sites. For this study spectral signatures were obtained on sotol (Dasylirion spp.) experimentally baked in an earth oven as well as sotol residue on an experimentally used processing tool. Inulin was the major residue component. The portable handheld Raman spectrometer also detected traces of inulin on boiling stones used to boil commercially obtained inulin. The Raman spectra of inulin and sotol may be useful as signatures of wild plant residues in archaeology. Spectroscopic analysis of millennia-old cook-stones from prehistoric archaeological sites in Fort Hood, TX revealed the presence of residues whose further identification requires improvement of current optical methods.

  3. Computer implemented method, and apparatus for controlling a hand-held tool (United States)

    Wagner, Kenneth William (Inventor); Taylor, James Clayton (Inventor)


    The invention described here in is a computer-implemented method and apparatus for controlling a hand-held tool. In particular, the control of a hand held tool is for the purpose of controlling the speed of a fastener interface mechanism and the torque applied to fasteners by the fastener interface mechanism of the hand-held tool and monitoring the operating parameters of the tool. The control is embodied in intool software embedded on a processor within the tool which also communicates with remote software. An operator can run the tool, or through the interaction of both software, operate the tool from a remote location, analyze data from a performance history recorded by the tool, and select various torque and speed parameters for each fastener.

  4. Enhanced Uranium Ore Concentrate Analysis by Handheld Raman Sensor: FY15 Status Report

    Energy Technology Data Exchange (ETDEWEB)

    Bryan, Samuel A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnson, Timothy J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Orton, Christopher R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)


    High-purity uranium ore concentrates (UOC) represent a potential proliferation concern. A cost-effective, “point and shoot” in-field analysis capability to identify ore types, phases of materials present, and impurities, as well as estimate the overall purity would be prudent. Handheld, Raman-based sensor systems are capable of identifying chemical properties of liquid and solid materials. While handheld Raman systems have been extensively applied to many other applications, they have not been broadly studied for application to UOC, nor have they been optimized for this class of chemical compounds. PNNL was tasked in Fiscal Year 2015 by the Office of International Safeguards (NA-241) to explore the use of Raman for UOC analysis and characterization. This report summarizes the activities in FY15 related to this project.

  5. A handheld support system to facilitate stereological measurements and mapping of branching structures

    DEFF Research Database (Denmark)

    Gardi, Jonathan Eyal; Wulfsohn, Dvoralai; Nyengaard, Jens Randel


    ‘BranchSampler' is a system for computer-assisted manual stereology written for handheld devices running Windows CE. The system has been designed specifically to streamline data collection and optimize sampling of tree-like branching structures, with particular aims of reducing user errors, savin...... in a specific generation (3) mapping fruit (apple) tree yield in an orchard, and (4) estimating the total leaf surface area of chrysanthemum plants in a greenhouse.......‘BranchSampler' is a system for computer-assisted manual stereology written for handheld devices running Windows CE. The system has been designed specifically to streamline data collection and optimize sampling of tree-like branching structures, with particular aims of reducing user errors, saving...

  6. Design of an Optical Character Recognition System for Camera-based Handheld Devices

    Directory of Open Access Journals (Sweden)

    Ayatullah Faruk Mollah


    Full Text Available This paper presents a complete Optical Character Recognition (OCR system for camera captured image/graphics embedded textual documents for handheld devices. At first, text regions are extracted and skew corrected. Then, these regions are binarized and segmented into lines and characters. Characters are passed into the recognition module. Experimenting with a set of 100 business card images, captured by cell phone camera, we have achieved a maximum recognition accuracy of 92.74%. Compared to Tesseract, an open source desktop-based powerful OCR engine, present recognition accuracy is worth contributing. Moreover, the developed technique is computationally efficient and consumes low memory so as to be applicable on handheld devices.

  7. A conceptual application for computer-based procedures for handheld devices

    Energy Technology Data Exchange (ETDEWEB)

    Sofie, Lunde-Hanssen Linda [Industrial Psychology, Institute for Energy Technology, Halden (Norway)


    This paper describes the concepts and proposed design principles for an application for computer-based procedures (CBPs) for field operators in the nuclear domain (so-called handheld procedures). The concept is focused on the field operators' work with procedures and the communication and coordination between field operators and control room operators. The goal is to overcome challenges with shared situation awareness (SA) in a distributed team by providing effective and usable information design. An iterative design method and user-centred design is used for tailoring the concept to the context of field operations. The resulting concept supports the execution of procedures where close collaboration is needed between control room and field operations, e.g. where particular procedure steps are executed from remote control points and others from the control room. The resulting conceptual application for CBPs on handheld devices is developed for mitigating the SA challenges and designing for usability and ease of use.

  8. Modeling movements of a long hand-held tool with effects of moments of inertia. (United States)

    Lin, Chiuhsiang Joe; Chen, Hung-Jen


    The current experiment aimed to investigate the effects of weight position on movement time in target acquisition tasks. Subsequently, a simple mathematical model was developed to describe the movement time with the moments of inertia. Ten right-handed participants conducted continuous Fitts pointing tasks using a laparoscopic instrument as a long hand-held tool. The results showed significant effects of weight position on movement time. Furthermore, an extended Fitts' law model is proposed for the moments of inertia produced by the hand, instrument, and a constant mass in different positions. This predictive model accounted for 63% of the variance in movement time. The predictive model proposed in the present study can be applied not only to estimate movement time given a particular target width, instrument movement amplitude, and weight position of a long hand-held tool but also to standardize movement time and establish training standards.

  9. Hand-held cow horn: Resurgence of an old arm or a potential terrorist weapon

    Directory of Open Access Journals (Sweden)

    Lawal Khalid


    Full Text Available A 23 year old man presented with intestinal evisceration from stab injury to the left side of the abdomen with a hand-held cow horn at a local night party. He complained of severe abdominal pain and bleeding at the site of injury. He was hemodynamically stable. At emergency exploration, the eviscerated bowel was viable with no adjacent mesenteric tear. Other intra abdominal organs were normal. The eviscerated bowel was lavaged and reduced into the abdomen through the 7cm anterior abdominal wall laceration. The laceration was repaired and abdomen closed in layers. Post operative recovery was uneventful. The hand-held cow horn can easily be concealed and may pass through security checks undetected. It should be added to the ever increasing list of weapons of small scale terror.

  10. Hand-held cow horn: resurgence of an old arm or apotential terrorist weapon (United States)

    Khalid, Lawal; Ahmed, Adamu


    Abstract: A 23 year old man presented with intestinal evisceration from stab injury to the left side of the abdomen with a hand-held cow horn at a local night party. He complained of severe abdominal pain and bleeding at the site of injury. He was hemodynamically stable. At emergency exploration, the eviscerated bowel was viable with no adjacent mesenteric tear. Other intra abdominal organs were normal. The eviscerated bowel was lavaged and reduced into the abdomen through the 7cm anterior abdominal wall laceration. The laceration was repaired and abdomen closed in layers. Post operative recovery was uneventful. The hand-held cow horn can easily be concealed and may pass through security checks undetected. It should be added to the ever increasing list of weapons of small scale terror. PMID:21502787

  11. Hand-held internet tablets for school-based data collection

    Directory of Open Access Journals (Sweden)

    Merry Sally N


    Full Text Available Abstract Background In the last 20 years, researchers have been using computer self-administered questionnaires to gather data on a wide range of adolescent health related behaviours. More recently, researchers collecting data in schools have started to use smaller hand-held computers for their ease of use and portability. The aim of this study is to describe a new technology with wi-fi enabled hand-held internet tablets and to compare adolescent preferences of laptop computers or hand-held internet tablets in administering a youth health and well-being questionnaire in a school setting. Methods A total of 177 students took part in a pilot study of a national youth health and wellbeing survey. Students were randomly assigned to internet tablets or laptops at the start of the survey and were changed to the alternate mode of administration about half-way through the questionnaire. Students at the end of the questionnaire were asked which of the two modes of administration (1 they preferred, (2 was easier to use, (3 was more private and confidential, and (4 was easier to answer truthfully. Results Many students expressed no preference between laptop computers or internet tablets. However, among the students who expressed a preference between laptop computers or internet tablets, the majority of students found the internet tablets more private and confidential (p Conclusion This study demonstrates that using wi-fi enabled hand-held internet tablets is a feasible methodology for school-based surveys especially when asking about sensitive information.

  12. Why has the US Army Been Slow to Adopt Modern Handheld Technology? (United States)


    contractors. The 2011 Network Evaluation Exercise tested apps that 8Ibid. 9“Inspecting Gadgets ,” AUSA, Association of the United States Army, http...product delivery.15 In response, the US Army sought ways that the handheld device market could augment its operational efficiency. In effect , the US Army...process has four phases, each phase marked by a milestone denoting progress in the acquisition process. In effect , any equipment under consideration

  13. [Design of hand-held heart rate variability acquisition and analysis system]. (United States)

    Li, Kaiyuan; Wang, Buqing; Wang, Weidong


    A design of handheld heart rate variability acquisition and analysis system is proposed. The system collects and stores the patient's ECG every five minutes through both hands touching on the electrodes, and then -uploads data to a PC through USB port. The system uses software written in LabVIEW to analyze heart rate variability parameters, The parameters calculated function is programmed and generated to components in Matlab.

  14. A Handheld Device for the In Situ Acquisition of Multimodal Tactile Sensing Data



    Multimodal tactile sensing could potentially enable robots to improve their performance at manipulation tasks by rapidly discriminating between task-relevant objects. Data-driven approaches to this tactile perception problem show promise, but there is a dearth of suitable training data. In this two-page paper, we present a portable handheld device for the efficient acquisition of multimodal tactile sensing data from objects in their natural settings, such as homes. The multimodal tactile sens...

  15. Internal Antenna for Digital Video Broadcasting-Handheld (DVB-H) Application (United States)

    Yu, Yeonsik; Kim, Jeongpyo; Choi, Jaehoon

    An internal antenna with a system ground for digital video broadcasting-handheld (DVB-H) service is proposed. The proposed antenna consists of a main patch with a two-step slit, two additional elements, and a system ground. The antenna has a small volume, 36mm×11mm×6mm, and an average gain of -2.22dBi to -0.06dBi over the DVB-H band.

  16. Handheld Fluorescence Resonance Energy Transfer (FRET)-Aptamer Sensor for Bone Markers (United States)

    Bruno, John G.


    Astronauts lose significant bone mass during lengthy space flights. NASA wishes to monitor this bone loss in order to develop nutritional and exercise countermeasures. Operational Technologies Corporation (OpTech) has developed a handheld device that quantifies bone loss in a spacecraft environment. The innovation works by adding fluorescent dyes and quenchers to aptamers to enable pushbutton, one-step bind-and-detect FRET assays that can be freeze-dried, rehydrated with body fluids, and used to quantify bone loss.

  17. A Method to Build a Super Small but Practically Accurate Language Model for Handheld Devices

    Institute of Scientific and Technical Information of China (English)

    WU GenQing (吴根清); ZHENG Fang (郑方)


    In this paper, an important question, whether a small language model can be practically accurate enough, is raised. Afterwards, the purpose of a language model, the problems that a language model faces, and the factors that affect the performance of a language model,are analyzed. Finally, a novel method for language model compression is proposed, which makes the large language model usable for applications in handheld devices, such as mobiles, smart phones, personal digital assistants (PDAs), and handheld personal computers (HPCs). In the proposed language model compression method, three aspects are included. First, the language model parameters are analyzed and a criterion based on the importance measure of n-grams is used to determine which n-grams should be kept and which removed. Second, a piecewise linear warping method is proposed to be used to compress the uni-gram count values in the full language model. And third, a rank-based quantization method is adopted to quantize the bi-gram probability values. Experiments show that by using this compression method the language model can be reduced dramatically to only about 1M bytes while the performance almost does not decrease. This provides good evidence that a language model compressed by means of a well-designed compression technique is practically accurate enough, and it makes the language model usable in handheld devices.

  18. Driver performance while text messaging using handheld and in-vehicle systems. (United States)

    Owens, Justin M; McLaughlin, Shane B; Sudweeks, Jeremy


    This study presents an evaluation of driver performance while text messaging via handheld mobile phones and an in-vehicle texting system. Participants sent and received text messages while driving with an experimenter on a closed-road course, using their personal mobile phones and the vehicle's system. The test vehicle was an instrumented 2010 Mercury Mariner equipped with an OEM in-vehicle system that supports text messaging and voice control of mobile devices via Bluetooth, which was modified to allow text message sending during driving. Twenty participants were tested, 11 younger (19-34) and 9 older (39-51). All participants were regular users of the in-vehicle system, although none had experience with the texting functions. Results indicated that handheld text message sending and receiving resulted in higher mental demand, more frequent and longer glances away from the roadway, and degraded steering measures compared to baseline. Using the in-vehicle system to send messages showed less performance degradation, but still had more task-related interior glance time and higher mental demand than baseline; using the system's text-to-speech functionality for incoming messages showed no differences from baseline. These findings suggest that using handheld phones to send and receive text messages may interfere with drivers' visual and steering behaviors; the in-vehicle system showed improvement, but performance was not at baseline levels during message sending.

  19. Gen-2 hand-held optical imager towards cancer imaging: reflectance and transillumination phantom studies. (United States)

    Gonzalez, Jean; Roman, Manuela; Hall, Michael; Godavarty, Anuradha


    Hand-held near-infrared (NIR) optical imagers are developed by various researchers towards non-invasive clinical breast imaging. Unlike these existing imagers that can perform only reflectance imaging, a generation-2 (Gen-2) hand-held optical imager has been recently developed to perform both reflectance and transillumination imaging. The unique forked design of the hand-held probe head(s) allows for reflectance imaging (as in ultrasound) and transillumination or compressed imaging (as in X-ray mammography). Phantom studies were performed to demonstrate two-dimensional (2D) target detection via reflectance and transillumination imaging at various target depths (1-5 cm deep) and using simultaneous multiple point illumination approach. It was observed that 0.45 cc targets were detected up to 5 cm deep during transillumination, but limited to 2.5 cm deep during reflectance imaging. Additionally, implementing appropriate data post-processing techniques along with a polynomial fitting approach, to plot 2D surface contours of the detected signal, yields distinct target detectability and localization. The ability of the gen-2 imager to perform both reflectance and transillumination imaging allows its direct comparison to ultrasound and X-ray mammography results, respectively, in future clinical breast imaging studies.

  20. MEMS-based handheld fourier domain Doppler optical coherence tomography for intraoperative microvascular anastomosis imaging.

    Directory of Open Access Journals (Sweden)

    Yong Huang

    Full Text Available To demonstrate the feasibility of a miniature handheld optical coherence tomography (OCT imager for real time intraoperative vascular patency evaluation in the setting of super-microsurgical vessel anastomosis.A novel handheld imager Fourier domain Doppler optical coherence tomography based on a 1.3-µm central wavelength swept source for extravascular imaging was developed. The imager was minimized through the adoption of a 2.4-mm diameter microelectromechanical systems (MEMS scanning mirror, additionally a 12.7-mm diameter lens system was designed and combined with the MEMS mirror to achieve a small form factor that optimize functionality as a handheld extravascular OCT imager. To evaluate in-vivo applicability, super-microsurgical vessel anastomosis was performed in a mouse femoral vessel cut and repair model employing conventional interrupted suture technique as well as a novel non-suture cuff technique. Vascular anastomosis patency after clinically successful repair was evaluated using the novel handheld OCT imager.With an adjustable lateral image field of view up to 1.5 mm by 1.5 mm, high-resolution simultaneous structural and flow imaging of the blood vessels were successfully acquired for BALB/C mouse after orthotopic hind limb transplantation using a non-suture cuff technique and BALB/C mouse after femoral artery anastomosis using a suture technique. We experimentally quantify the axial and lateral resolution of the OCT to be 12.6 µm in air and 17.5 µm respectively. The OCT has a sensitivity of 84 dB and sensitivity roll-off of 5.7 dB/mm over an imaging range of 5 mm. Imaging with a frame rate of 36 Hz for an image size of 1000(lateral×512(axial pixels using a 50,000 A-lines per second swept source was achieved. Quantitative vessel lumen patency, lumen narrowing and thrombosis analysis were performed based on acquired structure and Doppler images.A miniature handheld OCT imager that can be used for intraoperative evaluation of

  1. A New Handheld Device for the Detection of Falsified Medicines: Demonstration on Falsified Artemisinin-Based Therapies from the Field. (United States)

    Wilson, Benjamin K; Kaur, Harparkash; Allan, Elizabeth Louise; Lozama, Anthony; Bell, David


    Poor-quality medicines are a major problem for health-care systems in resource-poor settings as identifying falsified medicines requires a complex laboratory infrastructure such as a Medicines Quality Control Laboratory. We report here an evaluation of a low-cost, handheld near-infrared spectrometer (NIRS) device by analyzing a library of artemisinin-based combination therapy (ACT) medicines to determine its usefulness as a drug-screening tool. The "SCiO" research prototype device was used to collect NIR spectra of a library of ACT and artesunate monotherapy medicine samples previously collected in Bioko Island and Equatorial Guinea and Kintampo, Ghana. The quality of these samples had been categorized as falsified, substandard, and quality assured based on the amount of stated active pharmaceutical ingredients detected using high-performance liquid chromatography photodiode array. Numerical analyses were performed on the NIR spectra to assess the usefulness of NIR to identify falsified and substandard medicines. The NIRS device was successful at detecting falsified medicines in all cases where the library contained both quality assured and falsified medicines of the same stated brand of medicines. The NIRS device was successful at identifying substandard amounts of artesunate but not amodiaquine in the ACT samples (N = 15) of artesunate-amodiaquine. This work reveals that this low-cost, portable NIRS device is promising for screening ACTs for falsified samples and could enable widespread drug screening at all points of the health system.

  2. Comparison of a digital and an optical analogue hand-held refractometer for the measurement of canine urine specific gravity. (United States)

    Paris, J K; Bennett, A D; Dodkin, S J; Gunn-Moore, D A


    Urine specific gravity (USG) is used clinically as a measure of urine concentration, and is routinely assessed by refractometry. A comparison between optical analogue and digital refractometers for evaluation of canine urine has not been reported. The aim of this study was to compare a digital and an optical analogue hand-held refractometer for the measurement of canine USG, and to assess correlation with urine osmolality. Prospective study. Free-catch urine samples were collected from 285 hospitalised adult dogs, and paired USG readings were obtained with a digital and an optical analogue refractometer. In 50 dogs, urine osmolality was also measured using a freezing point depression osmometer. There was a small but statistically significant difference between the two refractometers (Panalogue refractometer reading higher than the digital refractometer (mean difference 0.0006, sd 0.0012). Paired refractometer measurements varied by analogue and digital refractometer readings showed excellent correlation with osmolality (r=0.980 and r=0.977, respectively, P<0.001 in both cases). Despite statistical significance, the difference between the two refractometers is unlikely to be clinically significant. Both instruments provide an accurate assessment of USG in dogs.

  3. Dielectric Resonator Antenna Mounted on Cylindrical Ground Plane for Handheld RFID Reader at 5.8 GHz

    Directory of Open Access Journals (Sweden)

    Hend Abd El-Azem Malhat


    Full Text Available Dielectric resonator antenna (DRA mounted on cylindrical ground plane is investigated for handheld RFID reader applications at 5.8 GHz. The simplicity of the structure makes it practical in terms of cost, space, and ease of fabrication. The radiation characteristics of the antenna in free space and in the presence of a proposed compact reader device model and human hand are calculated. The antenna is circularly polarized and exhibits peak gain of 7.62 dB at 5.8 GHz with high front to back ratio of 15.5 dB. Using the same reader device model, a sequentially feeding 2×2 DRA array mounted on the same cylindrical ground plane is used for RFID reader antenna at 5.8 GHz. The array introduces high gain of 9.36 dB at 5.8 GHz with high front to back ratio of 10.48 dB. The 2×2 DRA array elements exhibit circular polarization over a frequency band of 1.1 GHz. The axial ratio is 1.1 dB at 5.8 GHz. The proposed reader model is simple and has a small size compared with that in the case of planar ground plane. The results are calculated using the finite element method (FEM and compared with that calculated using the finite integral technique (FIT.

  4. Application of handheld devices to field research among underserved construction worker populations: a workplace health assessment pilot study

    Directory of Open Access Journals (Sweden)

    Fleming Lora E


    Full Text Available Abstract Background Novel low-cost approaches for conducting rapid health assessments and health promotion interventions among underserved worker groups are needed. Recruitment and participation of construction workers is particularly challenging due to their often transient periods of work at any one construction site, and their limited time during work to participate in such studies. In the present methodology report, we discuss the experience, advantages and disadvantages of using touch screen handheld devices for the collection of field data from a largely underserved worker population. Methods In March 2010, a workplace-centered pilot study to examine the feasibility of using a handheld personal device for the rapid health assessment of construction workers in two South Florida Construction sites was undertaken. A 45-item survey instrument, including health-related questions on tobacco exposure, workplace safety practices, musculoskeletal disorders and health symptoms, was programmed onto Apple iPod Touch® devices. Language sensitive (English and Spanish recruitment scripts, verbal consent forms, and survey questions were all preloaded onto the handheld devices. The experience (time to survey administration and capital cost of the handheld administration method was recorded and compared to approaches available in the extant literature. Results Construction workers were very receptive to the recruitment, interview and assessment processes conducted through the handheld devices. Some workers even welcomed the opportunity to complete the questionnaire themselves using the touch screen handheld device. A list of advantages and disadvantages emerged from this experience that may be useful in the rapid health assessment of underserved populations working in a variety of environmental and occupational health settings. Conclusions Handheld devices, which are relatively inexpensive, minimize survey response error, and allow for easy storage of data

  5. Radiation safety of handheld mobile phones and base stations

    Energy Technology Data Exchange (ETDEWEB)

    Jokela, K.; Leszczynski, D.; Paile, W.; Salomaa, S.; Puranen, L.; Hyysalo, P


    The recent expansion of personal telecommunications has led to a rapid increase in the exposure of people to the radio-frequency (RF) radiation. Although the mobile phones are low power devices, the antenna is so close to the head that the local exposure may slightly exceed 2 W/kg, the current exposure limit for the local specific absorption rate SAR for the general public. The increase in the temperature is, however, too small to have any physiological significance. On the basis of experiments with cell cultures it is possible that other biological effects caused by some unknown non-thermal mechanism exist, but thus far there is no conclusive biological or epidemiological evidence to suggest any diseases or adverse physiological changes below the thermal threshold. The use of a mobile phone by a person wearing a pace-maker, is not recommended, if the immunity of the pace-maker has not been assured. The exposure caused by the base stations is in all practical cases well below the power density limits for general public. (author) 118 refs.

  6. A new hand-held optical reflectometer to measure enamel erosion: correlation with surface hardness and calcium release. (United States)

    Carvalho, Thiago Saads; Baumann, Tommy; Lussi, Adrian


    In the present study, the surface reflection intensity (SRI) was measured from enamel with different induced erosion degrees using a hand-held pen-size reflectometer (Hand-Held) and a Table-Top reflectometer. To validate the Hand-Held reflectometer, we correlated its optical signals with the change of surface microhardness (SMH), and amount of calcium released from the enamel samples during erosion. We used 124 tooth enamel specimens that were exposed to an erosive challenge of either 1, 2, 4, 6, 8, or 10 minutes. SRI and SMH were measured before and after the erosive challenge and we also measured the amount of calcium released to the citric acid. Relative SRI loss (rSRIloss) and relative SMH loss (rSMHloss) were calculated. rSRIloss from the Hand-Held and the Table-Top reflectometers were similar and significantly correlated to rSMHloss and calcium release. The regression analyses showed a significant association between rSRIloss from both reflectometers and rSMHloss and calcium, showing that both reflectometers can be used to measure erosive demineralization of enamel. The Hand-Held reflectometer is capable of assessing in vitro erosion, correlating to other commonly used methods. It is small, easy to handle and provides fast measurement, being a possible candidate to measure erosion in clinical studies.

  7. Handheld NIRS sensors for routine compound feed quality control: Real time analysis and field monitoring. (United States)

    Modroño, Sagrario; Soldado, Ana; Martínez-Fernández, Adela; de la Roza-Delgado, Begoña


    Significant advances achieved in different sensor technologies and computer processing data have made possible to respond the needs of livestock sector, providing precise and rapid information on feed composition, being an alternative to real time quality control on compound feed the use of handheld NIRS sensors. This work aimed to evaluate two hand-held portable NIR spectrophotometers for on-site and real time analysis of nutritive parameters in raw compound feed: Phazir 1624 Polychromix Inc (PhIR) and MicroNIR(TM) 1700 by JDSU (MICRO). For computing data, different combinations of pre-treatments and multivariate statistical methods have been assayed to extract the valuable information of spectra data and to develop appropriate calibrations. The calibration models displayed greatest predictive capacity for Crude Protein (CP), Crude Fiber (CF) and Starch (STCH) and the determination coefficients of cross validation were 0.90-0.88 for CP, 0.85-0.91 for CF, 0.89-0.88 and 0.89-0.91 for STCH using PhIR and MICRO instruments respectively. Dry Matter showed the lowest determination coefficients of cross validation 0.67-0.73. Accuracy achieved 99-101% for both NIRS instruments and no differences were found when applying tstudent-test comparing reference and predicted data. Results obtained with both instruments were compared by using standard deviation and not significant differences were observed at the 5% level. Results so far have demonstrated the potential of these handheld NIRS instruments proposed here to estimate the individual compound feeds composition changes at farms level instantly, time avoiding the disadvantage of moving the samples to the lab.

  8. A data-driven design evaluation tool for handheld device soft keyboards.

    Directory of Open Access Journals (Sweden)

    Matthieu B Trudeau

    Full Text Available Thumb interaction is a primary technique used to operate small handheld devices such as smartphones. Despite the different techniques involved in operating a handheld device compared to a personal computer, the keyboard layouts for both devices are similar. A handheld device keyboard that considers the physical capabilities of the thumb may improve user experience. We developed and applied a design evaluation tool for different geometries of the QWERTY keyboard using a performance evaluation model. The model utilizes previously collected data on thumb motor performance and posture for different tap locations and thumb movement directions. We calculated a performance index (PITOT, 0 is worst and 2 is best for 663 designs consisting in different combinations of three variables: the keyboard's radius of curvature (R (mm, orientation (O (°, and vertical location on the screen (L. The current standard keyboard performed poorly (PITOT = 0.28 compared to other designs considered. Keyboard location (L contributed to the greatest variability in performance out of the three design variables, suggesting that designers should modify this variable first. Performance was greatest for designs in the middle keyboard location. In addition, having a slightly upward curve (R = -20 mm and orientated perpendicular to the thumb's long axis (O = -20° improved performance to PITOT = 1.97. Poorest performances were associated with placement of the keyboard's spacebar in the bottom right corner of the screen (e.g., the worst was for R = 20 mm, O = 40°, L =  Bottom (PITOT = 0.09. While this evaluation tool can be used in the design process as an ergonomic reference to promote user motor performance, other design variables such as visual access and usability still remain unexplored.

  9. Evaluation of the Perkins handheld applanation tonometer in horses and cattle. (United States)

    Andrade, Silvia Franco; Kupper, Daniel Silva; Pinho, Luiz Fernando Rodrigues; Franco, Elizabeth Cunha; Prataviera, Marcus Vinícius Felix Fabri; Duarte, Rodrigo Rolim; Junqueira, José Ricardo Cecílio


    The objective of this study was to evaluate and validate the accuracy of the Perkins handheld applanation tonometer for measuring intraocular pressure (IOP) in horses and cattle. Both eyes of 10 adult horses and cattle were evaluated in a postmortem study. The eyes from 10 clinically normal adult horses and cattle were also examined after bilateral auriculopalpebral nerve block and topical anesthesia for an in vivo study. IOP was measured postmortem using direct manometry (measured with an aneroid manometer) and tonometry (measured with a Perkins handheld applanation tonometer). The correlation coefficients (r(2)) for the data from the postmortem manometry and Perkins tonometer study were 0.866 for horses and 0.864 for cattle. In the in vivo study, IOP in horses was 25.1 ± 2.9 mmHg (range 19.0~30.0 mmHg) as measured by manometry and 23.4 ± 3.2 mmHg (range 18.6~28.4 mmHg) according to tonometry. In cattle, IOP was found to be 19.7 ± 1.2 mmHg (range 18.0~22.0 mmHg) by manometry and 18.8 ± 1.7 mmHg (range 15.9~20.8 mmHg) by tonometry. There was a strong correlation between the IOP values obtained by direct ocular manometry and the tonometer in both horses and cattle. Our results demonstrate that the Perkins handheld tonometer could be an additional tool for accurately measuring IOP in equine and bovine eyes.

  10. Fusing Open Source Intelligence and Handheld Situational Awareness - Benghazi Case Study (United States)


    Little League World Series – Wireless Emergency Alert Service – MIT LL Next-Generation Incident Command System • Pluggable analysis engines...Specific Rule Set Application Layer User Interface Layer Task View User View Context Data View Alert View Legend Layer Logical Component Data Read

  11. 3D handheld laser scanner based approach for automatic identification and localization of EEG sensors. (United States)

    Koessler, Laurent; Cecchin, Thierry; Ternisien, Eric; Maillard, Louis


    This paper describes and assesses for the first time the use of a handheld 3D laser scanner for scalp EEG sensor localization and co-registration with magnetic resonance images. Study on five subjects showed that the scanner had an equivalent accuracy, a better repeatability, and was faster than the reference electromagnetic digitizer. According to electrical source imaging, somatosensory evoked potentials experiments validated its ability to give precise sensor localization. With our automatic labeling method, the data provided by the scanner could be directly introduced in the source localization studies.

  12. Aircrew exposure to handheld laser pointers: the potential for retinal damage. (United States)

    Houston, Stephen


    Aviation authorities around the world continue to report substantial growth in the incidence of laser devices being aimed at aircraft in flight. Despite government restrictions, affordable handheld laser devices, with a power of up to several thousand mW, are now easily obtainable via the Internet. Lasers of this power output and wavelength have a nominal ocular hazard distance of around 1000 ft (304.8 m). Aviation medical specialists should be aware these lasers have the potential to cause retinal damage when aircrew operating at low altitudes are exposed.

  13. Hand-Held Dynamometry Isometric Torque Reference Values for Children and Adolescents


    Hébert, Luc J.; Maltais, Désirée B.; Lepage, Céline; Saulnier, Joanne; Crête, Mélanie


    Purpose: To establish hand-held dynamometry (HHD) maximal isometric muscle torque (MIT) reference values for children and adolescents who are developing typically. Methods: The MIT of 10 upper and lower limb muscle groups was assessed in 351 Caucasian youth (4 years 2 months to 17 years) using a standardized HHD protocol, previously shown to be feasible, valid, and reliable. Results: The mean MIT and 95% confidence interval of the mean for all muscle groups, for each of the 14 age groups (1 y...

  14. Xsense: using nanotechnology to combine detection methods for high sensitivity handheld explosives detectors

    DEFF Research Database (Denmark)

    Schmidt, Michael Stenbæk; Kostesha, Natalie; Bosco, Filippo


    In an effort to produce a handheld explosives sensor the Xsense project has been initiated at the Technical University of Denmark in collaboration with a number of partners. Using micro- and nano technological approaches it will be attempted to integrate four detection principles into a single de...... device. At the end of the project, the consortium aims at having delivered a sensor platform consisting of four independent detector principles capable of detecting concentrations of TNT at sub parts-per-billion (ppb) concentrations and with a false positive rate less than 1 parts...

  15. Technological characteristics of digital video broadcasting: Handheld standard DVB-H

    Directory of Open Access Journals (Sweden)

    Andreja B. Samčović


    Full Text Available This paper gives an overview of the Digital Video Broadcasting - Handheld standard DVB-H, as a part of the DVB Project. This standard is based on the previous standard DVB-T, which was developed for the terrestrial digital television. The ways of DVB-H signal transmission are also described. Development of advanced technology enabled the digital video broadcasting over wireless portable terminals. This paper discusses the key technological features of the DVB-H standard, such as: time slicing, forward error correction, 4K mode and in-depth interleavers.

  16. The Case of the Druid Dracula (United States)

    Brickman, Peggy


    This article describes how case studies have been successfully implemented in an introductory biology course of 300+ students using available technologies ranging from WebCT, used to assign students to permanent small groups (as well as assign groups to regions of a large lecture hall), to hand-held response systems (aka "clickers"), which…

  17. Reliability and validity of standing balance assessment index using a hand-held dynamometer in stroke patients. (United States)

    Iwamoto, Koji; Yoshio, Masaharu; Takata, Yuichi; Kozuka, Naoki


    [Purpose] This study aimed to determine the reliability and validity of our standing balance assessment index using a hand-held dynamometer (the hand-held dynamometer assessment index) in stroke patients. [Subjects and Methods] The participants were 60 stroke patients with impaired standing balance. Intrarater and interrater reliabilities were evaluated employing the intraclass correlation coefficient. Criterion-related validity was evaluated by Spearman's rank correlation coefficient between the HHD assessment index and the functional balance scale. [Results] The intraclass correlation coefficient values obtained ranged from 0.91 to 0.98, and the correlation coefficient with the FBS was 0.83. [Conclusion] Our findings confirmed the reliability and validity of the hand-held dynamometer assessment index in stroke patients.

  18. Simple hand-held metal detectors are an effective means of detecting cardiac pacemakers in the deceased prior to cremation. (United States)

    Stone, Jason Lyle; Williams, John; Fearn, Lesley


    The hazard of undetected cardiac pacemakers exploding in crematoria is well described. This short report describes the use of an affordable hand-held metal detector to detect cardiac pacemakers. Over the course of a year, the metal detector located 100% of cardiac pacemakers in a district general hospital mortuary. A simple model using pigskin and fat is also used to demonstrate the effectiveness in vitro. Commercially purchased hand-held metal detectors should be used in all mortuaries responsible for detection and removal of cardiac pacemakers prior to cremation.

  19. Design and testing of prototype handheld scanning probes for optical coherence tomography. (United States)

    Demian, Dorin; Duma, Virgil-Florin; Sinescu, Cosmin; Negrutiu, Meda Lavinia; Cernat, Ramona; Topala, Florin Ionel; Hutiu, Gheorghe; Bradu, Adrian; Podoleanu, Adrian Gh


    Three simple and low-cost configurations of handheld scanning probes for optical coherence tomography have been developed. Their design and testing for dentistry applications are presented. The first two configurations were built exclusively from available off-the-shelf optomechanical components, which, to the best of our knowledge, are the first designs of this type. The third configuration includes these components in an optimized and ergonomic probe. All the designs are presented in detail to allow for their duplication in any laboratory with a minimum effort, for applications that range from educational to high-end clinical investigations. Requirements that have to be fulfilled to achieve configurations which are reliable, ergonomic-for clinical environments, and easy to build are presented. While a range of applications is possible for the prototypes developed, in this study the handheld probes are tested ex vivo with a spectral domain optical coherence tomography system built in-house, for dental constructs. A previous testing with a swept source optical coherence tomography system has also been performed both in vivo and ex vivo for ear, nose, and throat-in a medical environment. The applications use the capability of optical coherence tomography to achieve real-time, high-resolution, non-contact, and non-destructive interferometric investigations with micrometer resolutions and millimeter penetration depth inside the sample. In this study, testing the quality of the material of one of the most used types of dental prosthesis, metalo-ceramic is thus demonstrated.

  20. Smartphone based hand-held quantitative phase microscope using the transport of intensity equation method. (United States)

    Meng, Xin; Huang, Huachuan; Yan, Keding; Tian, Xiaolin; Yu, Wei; Cui, Haoyang; Kong, Yan; Xue, Liang; Liu, Cheng; Wang, Shouyu


    In order to realize high contrast imaging with portable devices for potential mobile healthcare, we demonstrate a hand-held smartphone based quantitative phase microscope using the transport of intensity equation method. With a cost-effective illumination source and compact microscope system, multi-focal images of samples can be captured by the smartphone's camera via manual focusing. Phase retrieval is performed using a self-developed Android application, which calculates sample phases from multi-plane intensities via solving the Poisson equation. We test the portable microscope using a random phase plate with known phases, and to further demonstrate its performance, a red blood cell smear, a Pap smear and monocot root and broad bean epidermis sections are also successfully imaged. Considering its advantages as an accurate, high-contrast, cost-effective and field-portable device, the smartphone based hand-held quantitative phase microscope is a promising tool which can be adopted in the future in remote healthcare and medical diagnosis.

  1. DNA aptamer beacon assay for C-telopeptide and handheld fluorometer to monitor bone resorption. (United States)

    Bruno, John Gordon; Carrillo, Maria P; Phillips, Taylor; Hanson, Douglas; Bohmann, Jonathan A


    A novel DNA aptamer beacon is described for quantification of a 26-amino acid C-telopeptide (CTx) of human type I bone collagen. One aptamer sequence and its reverse complement dominated the aptamer pool (31.6% of sequenced clones). Secondary structures of these aptamers were examined for potential binding pockets. Three-dimensional computer models which analyzed docking topologies and binding energies were in agreement with empirical fluorescence experiments used to select one candidate loop for beacon assay development. All loop structures from the aptamer finalists were end-labeled with TYE 665 and Iowa Black quencher for comparison of beacon fluorescence levels as a function of CTx concentration. The optimal beacon, designated CTx 2R-2h yielded a low ng/ml limit of detection using a commercially available handheld fluorometer. The CTx aptamer beacon bound full-length 26-amino acid CTx peptide, but not a shorter 8-amino acid segment of CTx peptide which is a common target for commercial CTx ELISA kits. The prototype assay was shown to detect CTx peptide from human urine after creatinine and urea were removed by size-exclusion chromatography to prevent nonspecific denaturing of the aptamer beacon. This work demonstrates the potential of aptamer beacons to be utilized for rapid and sensitive bone health monitoring in a handheld or point-of-care format.

  2. Estimation of antioxidant components of tomato using VIS-NIR reflectance data by handheld portable spectrometer (United States)

    Szuvandzsiev, Péter; Helyes, Lajos; Lugasi, Andrea; Szántó, Csongor; Baranowski, Piotr; Pék, Zoltán


    Processing tomato production represents an important part of the total production of processed vegetables in the world. The quality characteristics of processing tomato, important for the food industry, are soluble solids content and antioxidant content (such as lycopene and polyphenols) of the fruit. Analytical quantification of these components is destructive, time and labour consuming. That is why researchers try to develop a non-destructive and rapid method to assess those quality parameters. The present study reports the suitability of a portable handheld visible near infrared spectrometer to predict soluble solids, lycopene and polyphenol content of tomato fruit puree. Spectral ranges of 500-1000 nm were directly acquired on fruit puree of five different tomato varieties using a FieldSpec HandHeld 2™ Portable Spectroradiometer. Immediately after spectral measurement, each fruit sample was analysed to determine soluble solids, lycopene and polyphenol content. Partial least square regressions were carried out to create models of prediction between spectral data and the values obtained from the analytical results. The accuracy of the predictions was analysed according to the coefficient of determination value (R2), the root mean square error of calibration/ cross-validation.

  3. Sensor-Based Technique for Manually Scanned Hand-Held Optical Coherence Tomography Imaging

    Directory of Open Access Journals (Sweden)

    Paritosh Pande


    Full Text Available Hand-held optical coherence tomography (OCT imaging probes offer flexibility to image sites that are otherwise challenging to access. While the majority of hand-held imaging probes utilize galvanometer- or MEMS-scanning mirrors to transversely scan the imaging beam, these probes are commonly limited to lateral fields-of-view (FOV of only a few millimeters. The use of a freehand manually scanned probe can significantly increase the lateral FOV. However, using the traditional fixed-rate triggering scheme for data acquisition in a manually scanned probe results in imaging artifacts due to variations in the scan velocity of the imaging probe. These artifacts result in a structurally inaccurate image of the sample. In this paper, we present a sensor-based manual scanning technique for OCT imaging, where real-time feedback from an optical motion sensor is used to trigger data acquisition. This technique is able to circumvent the problem of motion artifacts during manual scanning by adaptively altering the trigger rate based on the instantaneous scan velocity, enabling OCT imaging over a large lateral FOV. The feasibility of the proposed technique is demonstrated by imaging several biological and nonbiological samples.

  4. Handheld non-contact evaluation of fastener flushness and countersink surface profiles using optical coherence tomography (United States)

    Wang, James H.; Wang, Michael R.


    We report the use of spectral domain optical coherence tomography (SD-OCT) for non-contact optical evaluation of fastener flushness and countersink surface profile. Using a handheld galvanometer scanner of only 0.5 lb in weight the SD-OCT can perform line scan surface profile measurement of fastener and countersink without demanding accurate scan center alignment. It demonstrates fast measurement of fastener flushness, radius, slant angle, as well as countersink edge radius and surface angle within 90 ms suitable for handheld operation. With the use of a broadband light source at 840 nm center wavelength and 45 nm spectral bandwidth and a lens of 60 mm focal length, the low coherence interferometry based SD-OCT measurement offers axial depth resolution of 8.5 μm, lateral resolution of 19 μm, and measurement depth of 3.65 mm in the air. Multi-line scans can yield 3D surface profiles of fastener and countersink.

  5. Handheld pose tracking using vision-inertial sensors with occlusion handling (United States)

    Li, Juan; Slembrouck, Maarten; Deboeverie, Francis; Bernardos, Ana M.; Besada, Juan A.; Veelaert, Peter; Aghajan, Hamid; Casar, José R.; Philips, Wilfried


    Tracking of a handheld device's three-dimensional (3-D) position and orientation is fundamental to various application domains, including augmented reality (AR), virtual reality, and interaction in smart spaces. Existing systems still offer limited performance in terms of accuracy, robustness, computational cost, and ease of deployment. We present a low-cost, accurate, and robust system for handheld pose tracking using fused vision and inertial data. The integration of measurements from embedded accelerometers reduces the number of unknown parameters in the six-degree-of-freedom pose calculation. The proposed system requires two light-emitting diode (LED) markers to be attached to the device, which are tracked by external cameras through a robust algorithm against illumination changes. Three data fusion methods have been proposed, including the triangulation-based stereo-vision system, constraint-based stereo-vision system with occlusion handling, and triangulation-based multivision system. Real-time demonstrations of the proposed system applied to AR and 3-D gaming are also included. The accuracy assessment of the proposed system is carried out by comparing with the data generated by the state-of-the-art commercial motion tracking system OptiTrack. Experimental results show that the proposed system has achieved high accuracy of few centimeters in position estimation and few degrees in orientation estimation.

  6. Correlation and Agreement of Handheld Spirometry with Laboratory Spirometry in Allogeneic Hematopoietic Cell Transplant Recipients. (United States)

    Cheng, Guang-Shing; Campbell, Angela P; Xie, Hu; Stednick, Zach; Callais, Cheryl; Leisenring, Wendy M; Englund, Janet A; Chien, Jason W; Boeckh, Michael


    Early detection of subclinical lung function decline may help identify allogeneic hematopoietic cell transplant (HCT) recipients who are at increased risk for late noninfectious pulmonary complications, including bronchiolitis obliterans syndrome. We evaluated the use of handheld spirometry in this population. Allogeneic HCT recipients enrolled in a single-center observational trial performed weekly spirometry with a handheld spirometer for 1 year after transplantation. Participants performed pulmonary function tests in an outpatient laboratory setting at 3 time points: before transplantation, at day 80 after transplantation, and at 1 year after transplantation. Correlation between the 2 methods was assessed by Pearson and Spearman correlations; agreement was assessed using Bland-Altman plots. A total of 437 subjects had evaluable pulmonary function tests. Correlation for forced expiratory volume in 1 second (FEV1) was r = .954 (P spirometry correlated well with laboratory spirometry after allogeneic HCT and may be useful for self-monitoring of patients for early identification of airflow obstruction.

  7. A Handheld Open-Field Infant Keratometer (An American Ophthalmological Society Thesis) (United States)

    Miller, Joseph M.


    Purpose: To design and evaluate a new infant keratometer that incorporates an unobstructed view of the infant with both eyes (open-field design). Methods: The design of the open-field infant keratometer is presented, and details of its construction are given. The design incorporates a single-ring keratoscope for measurement of corneal astigmatism over a 4-mm region of the cornea and includes a rectangular grid target concentric within the ring to allow for the study of higher-order aberrations of the eye. In order to calibrate the lens and imaging system, a novel telecentric test object was constructed and used. The system was bench calibrated against steel ball bearings of known dimensions and evaluated for accuracy while being used in handheld mode in a group of 16 adult cooperative subjects. It was then evaluated for testability in a group of 10 infants and toddlers. Results: Results indicate that while the device achieved the goal of creating an open-field instrument containing a single-ring keratoscope with a concentric grid array for the study of higher-order aberrations, additional work is required to establish better control of the vertex distance. Conclusion: The handheld open-field infant keratometer demonstrates testability suitable for the study of infant corneal astigmatism. Use of collimated light sources in future iterations of the design must be incorporated in order to achieve the accuracy required for clinical investigation. PMID:21212850

  8. Fluorescence-enhanced imaging using a novel hand-held based optical imager: phantom studies (United States)

    Ge, Jiajia; Zhu, Banghe; Regalado, Steven; Godavarty, Anuradha


    Near-infrared (NIR) optical imaging is an emerging noninvasive modality for breast cancer diagnosis. The currently available optical imaging systems towards tomography studies are limited either by instrument portability, patient comfort, or flexibility to image any given tissue volume. Hence, a novel hand-held probe based gain modulated intensified CCD camera imaging system is developed such that it can possibly overcome some of the above limitations. The unique features of this hand-held probe based optical imaging system are: (i) to perform simultaneous multiple point illumination and detection, thus decreasing the total imaging time and improving overall signal strength; (ii) to adapt to the tissue contours, thus decreasing the light leakage at contact surface; and (iii) to obtain trans-illumination measurements apart from reflectance measurements, thus improving the depth information. Phantom studies are performed to demonstrate the feasibility of performing fluorescence optical imaging under different target depths using cubical phantoms (10×6.5×10 cc). The effect of simultaneous multiple point illumination over sequential single point illumination is demonstrated from experimental phantom studies.

  9. Design and Implementation of an Intelligent Windowsill System Using Smart Handheld Device and Fuzzy Microcontroller. (United States)

    Wang, Jing-Min; Yang, Ming-Ta; Chen, Po-Lin


    With the advance of science and technology, people have a desire for convenient and comfortable living. Creating comfortable and healthy indoor environments is a major consideration for designing smart homes. As handheld devices become increasingly powerful and ubiquitous, this paper proposes an innovative use of smart handheld devices (SHD), using MIT App Inventor and fuzzy control, to perform the real-time monitoring and smart control of the designed intelligent windowsill system (IWS) in a smart home. A compact weather station that consists of environment sensors was constructed in the IWS for measuring of indoor illuminance, temperature-humidity, carbon dioxide (CO₂) concentration and outdoor rain and wind direction. According to the measured environment information, the proposed system can automatically send a command to a fuzzy microcontroller performed by Arduino UNO to fully or partly open the electric curtain and electric window for adapting to climate changes in the indoor and outdoor environment. Moreover, the IWS can automatically close windows for rain splashing on the window. The presented novel control method for the windowsill not only expands the SHD applications, but greatly enhances convenience to users. To validate the feasibility and effectiveness of the IWS, a laboratory prototype was built and confirmed experimentally.

  10. Curvelet filter based prescreener for explosive hazard detection in hand-held ground penetrating radar (United States)

    White, Julie L.; Anderson, Derek T.; Ball, John E.; Parker, Brian


    Explosive hazards, above and below ground, are a serious threat to civilians and soldiers. In an attempt to mitigate these threats, different forms of explosive hazard detection (EHD) exist; e.g., multi-sensor hand-held platforms, downward looking and forward looking vehicle mounted platforms, etc. Robust detection of these threats resides in the processing and fusion of different data from multiple sensing modalities, e.g., radar, infrared, electromagnetic induction (EMI), etc. Herein, we focus on a new energy-based prescreener in hand-held ground penetrating radar (GPR). First, we Curvelet filter B-scan signal data using either Reverse-Reconstruction followed by Enhancement (RRE) or selectivity with respect to wedge information in the Curvelet transform. Next, we aggregate the result of a bank of matched filters and run a size contrast filter with Bhattacharyya distance. Alarms are then combined using weighted mean shift clustering. Results are demonstrated in the context of receiver operating characteristics (ROC) curve performance on data from a U. S. Army test site that contains multiple target and clutter types, burial depths and times of the day.

  11. Finger tracking for hand-held device interface using profile-matching stereo vision (United States)

    Chang, Yung-Ping; Lee, Dah-Jye; Moore, Jason; Desai, Alok; Tippetts, Beau


    Hundreds of millions of people use hand-held devices frequently and control them by touching the screen with their fingers. If this method of operation is being used by people who are driving, the probability of deaths and accidents occurring substantially increases. With a non-contact control interface, people do not need to touch the screen. As a result, people will not need to pay as much attention to their phones and thus drive more safely than they would otherwise. This interface can be achieved with real-time stereovision. A novel Intensity Profile Shape-Matching Algorithm is able to obtain 3-D information from a pair of stereo images in real time. While this algorithm does have a trade-off between accuracy and processing speed, the result of this algorithm proves the accuracy is sufficient for the practical use of recognizing human poses and finger movement tracking. By choosing an interval of disparity, an object at a certain distance range can be segmented. In other words, we detect the object by its distance to the cameras. The advantage of this profile shape-matching algorithm is that detection of correspondences relies on the shape of profile and not on intensity values, which are subjected to lighting variations. Based on the resulting 3-D information, the movement of fingers in space from a specific distance can be determined. Finger location and movement can then be analyzed for non-contact control of hand-held devices.

  12. Handheld Thermoacoustic Scanning System Based on a Linear-array Transducer. (United States)

    Ji, Zhong; Ding, Wenzheng; Ye, Fanghao; Lou, Cunguang


    To receive the information necessary for imaging, traditional microwave-induced thermoacoustic imaging systems (MITISs) use a type of circular-scanning mode using single or arc detectors. However, the use of MITISs for body scanning is complicated by restrictions in space and imaging time. A linear-array detector, the most widely used transducer in medical ultrasound imaging systems for body scanning, is a possible alternative to MITISs for scanning biological tissues, such as from the breast or limbs. In this paper, a handheld MITIS, based on a linear-array detector and a multiple data acquisition system, is described, and the capacity of the system is explored experimentally. First, the vertical and lateral resolution of the system is discussed. Next, real-time imaging of a moving object, obtained with an image capture rate of 20 frame/s, is described. Finally, a phantom experiment is detailed, investigating the overall imaging capability. The results show that this system achieves rapid scanning with a large field of view. The system has the obvious advantages of being handheld, not using coupled fluids, and achieving real-time imaging with a large field of view, which make this MITIS more suitable for clinical applications.

  13. Rich internet application system for patient-centric healthcare data management using handheld devices. (United States)

    Constantinescu, L; Pradana, R; Kim, J; Gong, P; Fulham, Michael; Feng, D


    Rich Internet Applications (RIAs) are an emerging software platform that blurs the line between web service and native application, and is a powerful tool for handheld device deployment. By democratizing health data management and widening its availability, this software platform has the potential to revolutionize telemedicine, clinical practice, medical education and information distribution, particularly in rural areas, and to make patient-centric medical computing a reality. In this paper, we propose a telemedicine application that leverages the ability of a mobile RIA platform to transcode, organise and present textual and multimedia data, which are sourced from medical database software. We adopted a web-based approach to communicate, in real-time, with an established hospital information system via a custom RIA. The proposed solution allows communication between handheld devices and a hospital information system for media streaming with support for real-time encryption, on any RIA enabled platform. We demonstrate our prototype's ability to securely and rapidly access, without installation requirements, medical data ranging from simple textual records to multi-slice PET-CT images and maximum intensity (MIP) projections.

  14. Evolving Consumption Patterns of Various Information Media via Handheld Mobile Devices

    Directory of Open Access Journals (Sweden)

    Nitza Geri


    Full Text Available This study examines diverse information media in order to identify those formats that are most suitable for consumption via handheld mobile devices, namely, smartphones and tablets. The preferences of the users are measured objectively by analyzing actual data of their relative use of handheld mobile devices and personal computing (PC desktop devices, including laptops and notebooks, for consumption of information presented in various formats. Our findings are based on Google Analytics pageview data of five course Websites during a period of three semesters, by 11,557 undergraduate students. M-learning contexts were chosen, since in a learning environment the interests of information providers (i.e., the instructors are in accord with those of the information consumers (i.e., the students, whereas in commercial settings there may be conflicts of interests. Our findings demonstrate that although about 90% of the pageviews were via PC devices, the rate of smartphone use for consuming learning content in diverse information media is gradually increasing as time goes by, whereas the rate of tablet use for these purposes is stagnant. The most promising direction for smartphone development, emanating from the findings, is online video content.

  15. Handheld computers for data entry: high tech has its problems too

    Directory of Open Access Journals (Sweden)

    Abernethy Amy P


    Full Text Available Abstract Background The use of handheld computers in medicine has increased in the last decade, they are now used in a variety of clinical settings. There is an underlying assumption that electronic data capture is more accurate that paper-based data methods have been rarely tested. This report documents a study to compare the accuracy of hand held computer data capture versus more traditional paper-based methods. Methods Clinical nurses involved in a randomised controlled trial collected patient information on a hand held computer in parallel with a paper-based data form. Both sets of data were entered into an access database and the hand held computer data compared to the paper-based data for discrepancies. Results Error rates from the handheld computers were 67.5 error per 1000 fields, compared to the accepted error rate of 10 per 10,000 field for paper-based double data entry. Error rates were highest in field containing a default value. Conclusion While popular with staff, unacceptable high error rates occurred with hand held computers. Training and ongoing monitoring are needed if hand held computers are to be used for clinical data collection.

  16. Handheld Reflective Foil Emissometer with 0.007 Absolute Accuracy at 0.05 (United States)

    van der Ham, E. W. M.; Ballico, M. J.


    The development and performance of a handheld emissometer for the measurement of the emissivity of highly reflective metallic foils used for the insulation of domestic and commercial buildings are described. Reflective roofing insulation based on a thin coating of metal on a more robust substrate is very widely used in hotter climates to reduce the radiant heat transfer between the ceiling and roof in commercial and residential buildings. The required normal emissivity of these foils is generally below 0.05, so stray reflected ambient infrared radiation (IR) makes traditional reflectance-based measurements of emissivity very difficult to achieve with the required accuracy. Many manufacturers apply additional coatings onto the metallic foil to reduce visible glare during installation on a roof, and to provide protection to the thin reflective layer; however, this layer can also substantially increase the IR emissivity. The system as developed at the National Measurement Institute, Australia (NMIA) is based on the principle of measurement of the modulation in thermal infrared radiation, as the sample is thermally modulated by hot and cold air streams. A commercial infrared to band radiation thermometer with a highly specialized stray and reflected radiation shroud attachment is used as the detector system, allowing for convenient handheld field measurements. The performance and accuracy of the system have been compared with NMIA's reference emissometer systems for a number of typical material samples, demonstrating its capability to measure the absolute thermal emissivity of these very highly reflective foils with an uncertainty of better than.

  17. The Case of the Druid Dracula: A Directed "Clicker" Case Study on DNA Fingerprinting (United States)

    Brickman, Peggy


    This article describes how case studies have been successfully implemented in an introductory biology course of 300+ students using available technologies ranging from WebCT, used to assign students to permanent small groups (as well as assign groups to regions of a large lecture hall), to hand-held response systems (aka "clickers"), which…

  18. The Pixel Paradox and Transition-Metal Spectroscopy: One of Many Uses of the Handheld Digital Microscope in Chemical Demonstrations (United States)

    Vitz, Ed


    A handheld digital microscope (HDM) interfaced to a computer with a presentation projector is used to project an out-of-focus yellow patch on the screen, then the patch is brought into focus to show that, paradoxically, there are red and green but no yellow pixels. Chromaticity diagrams are used to discuss this observation and spectroscopic…

  19. Handheld E-Book Readers and Scholarship Report and Reader Survey: ACLS Humanities E-Book. White Paper No. 3 (United States)

    Gielen, Nina


    This report describes a conversion experiment and subsequent reader survey conducted by the American Council of Learned Societies (ACLS) Humanities E-Book (HEB) in late 2009 and early 2010 to assess the viability of using scholarly monographs with handheld e-readers. As sample content, HEB selected six titles from its own online collection, three…


    Directory of Open Access Journals (Sweden)

    Julia Paredes


    Full Text Available Organic chemistry instructors integrate handheld technology and applications into course lecture and lab to engage students with tools and techniques students use in the modern world. This technology and applications enable instructors to re-visit the Thayer Method of teaching and learning to create an updated method that works with 21st century students. The Thayer Method is based on the premise that students are willing and capable of making substantial preparation before coming to class and lab in order to maximize efficiency of student-instructor contact time. During this student preparation phase, we engage students with handheld technology and content applications including smart phone viewable course administrative materials; “flashcards” containing basic organic chemistry nomenclature, molecular structures, and chemical reactions; mini-lectures prepared using the Smart Board Airliner Interactive Tablet for upcoming class periods and laboratory technique videos demonstrating tasks they will perform as part of laboratory experimentation. Coupled with a student friendly course text, these handheld applications enable substantial student preparation before class and lab. The method, in conjunction with handheld technology and applications, has been used with positive results in our organic chemistry courses.

  1. Guiding brain tumor resection using surface-enhanced Raman scattering nanoparticles and a hand-held Raman scanner. (United States)

    Karabeber, Hazem; Huang, Ruimin; Iacono, Pasquale; Samii, Jason M; Pitter, Ken; Holland, Eric C; Kircher, Moritz F


    The current difficulty in visualizing the true extent of malignant brain tumors during surgical resection represents one of the major reasons for the poor prognosis of brain tumor patients. Here, we evaluated the ability of a hand-held Raman scanner, guided by surface-enhanced Raman scattering (SERS) nanoparticles, to identify the microscopic tumor extent in a genetically engineered RCAS/tv-a glioblastoma mouse model. In a simulated intraoperative scenario, we tested both a static Raman imaging device and a mobile, hand-held Raman scanner. We show that SERS image-guided resection is more accurate than resection using white light visualization alone. Both methods complemented each other, and correlation with histology showed that SERS nanoparticles accurately outlined the extent of the tumors. Importantly, the hand-held Raman probe not only allowed near real-time scanning, but also detected additional microscopic foci of cancer in the resection bed that were not seen on static SERS images and would otherwise have been missed. This technology has a strong potential for clinical translation because it uses inert gold-silica SERS nanoparticles and a hand-held Raman scanner that can guide brain tumor resection in the operating room.

  2. Manipulator Design and Operation for a Six-Degree-of-Freedom Handheld Tremor-Canceling Microsurgical Instrument. (United States)

    Yang, Sungwook; MacLachlan, Robert A; Riviere, Cameron N


    This paper presents the design and actuation of a six-degree-of-freedom (6-DOF) manipulator for a handheld instrument, known as "Micron," which performs active tremor compensation during microsurgery. The design incorporates a Gough-Stewart platform based on piezoelectric linear motor, with a specified minimum workspace of a cylinder 4 mm long and 4 mm in diameter at the end-effector. Given the stall force of the motors and the loading typically encountered in vitreoretinal microsurgery, the dimensions of the manipulator are optimized to tolerate a transverse load of 0.2 N on a remote center of motion near the midpoint of the tool shaft. The optimization yields a base diameter of 23 mm and a height of 37 mm. The fully handheld instrument includes a custom-built optical tracking system for control feedback, and an ergonomic housing to serve as a handle. The manipulation performance was investigated in both clamped and handheld conditions. In positioning experiments with varying side loads, the manipulator tolerates side load up to 0.25 N while tracking a sinusoidal target trajectory with less than 20 μm error. Physiological hand tremor is reduced by about 90% in a pointing task, and error less than 25 μm is achieved in handheld circle-tracing.

  3. A Scaffolding Strategy to Develop Handheld Sensor-Based Vocabulary Games for Improving Students' Learning Motivation and Performance (United States)

    Huang, Yong-Ming; Huang, Yueh-Min


    Vocabulary is the foundation for students who learn a foreign language. Nevertheless, students may be bored by the painstaking process of rote learning. To this end, this study designed a handheld sensor-based vocabulary game based on a scaffolding strategy for improving students' motivation and achievement in vocabulary learning. On the one hand,…

  4. High-Tech versus Low-Tech Instructional Strategies: A Comparison of Clickers and Handheld Response Cards (United States)

    Fallon, Marianne; Forrest, Stacey L.


    Although the use of clickers (classroom response systems) has been widely investigated, fewer studies directly compared outcomes for clickers with other active response methods, such as handheld response cards. We measured students' test performance and their self-reported anxiety and hope for upcoming tests after attending review sessions for an…

  5. Linear Text vs. Non-Linear Hypertext in Handheld Computers: Effects on Declarative and Structural Knowledge, and Learner Motivation (United States)

    Son, Chanhee; Park, Sanghoon; Kim, Minjeong


    This study compared linear text-based and non-linear hypertext-based instruction in a handheld computer regarding effects on two different levels of knowledge (declarative and structural knowledge) and learner motivation. Forty four participants were randomly assigned to one of three experimental conditions: linear text, hierarchical hypertext,…

  6. In vivo cellular-resolution retinal imaging in infants and children using an ultracompact handheld probe (United States)

    Larocca, Francesco; Nankivil, Derek; Dubose, Theodore; Toth, Cynthia A.; Farsiu, Sina; Izatt, Joseph A.


    Enabled by adaptive optics, retinal photoreceptor cell imaging is changing our understanding of retinal structure and function, as well as the pathogenesis of numerous ocular diseases. To date, use of this technology has been limited to cooperative adult subjects due to the size, weight and inconvenience of the equipment, thus excluding study of retinal maturation during human development. Here, we report the design and operation of a handheld probe that can perform both scanning laser ophthalmoscopy and optical coherence tomography of the parafoveal photoreceptor structure in infants and children without the need for adaptive optics. The probe, featuring a compact optical design weighing only 94 g, was able to quantify packing densities of parafoveal cone photoreceptors and visualize cross-sectional photoreceptor substructure in children with ages ranging from 14 months to 12 years. The probe will benefit paediatric research by improving the understanding of retinal development, maldevelopment and early onset of disease during human growth.

  7. Textbooks on tap: using electronic books housed in handheld devices in nursing clinical courses. (United States)

    Williams, Margaret G; Dittmer, Arlis


    Changing technology is creating new ways to approach nursing education and practice. Beginning in 2003, using a quasi-experimental design, this project introduced personal digital assistants (PDAs) as a clinical tool to five experimental and control groups of students and faculty. The handheld device, or PDA, was loaded with e-books for clinical practice. Differences in learning styles and preferences emerged during the different phases of the study. Students were quickly able to master the technology and use the device effectively, reporting that they liked the concise nature of the information obtained. No students expressed dissatisfaction or regret at being in the experimental group. Results and implications for clinical practice, education, and library resources are discussed.

  8. A handheld low temperature atmospheric pressure air plasma gun for nanomaterial synthesis in liquid phase (United States)

    Yu, Shuang; Wang, Kaile; Zuo, Shasha; Liu, Jiahui; Zhang, Jue; Fang, Jing


    A handheld low temperature atmospheric pressure air plasma gun based on a dielectric barrier structure with hollow electrodes was proposed. The portable plasma gun with an embedded mini air pump was driven by a 12 V direct voltage battery. The air plasma jet generated from the gun could be touched without a common shock hazard. Besides working in air, the plasma gun can also work in water. The diagnostic result of optical emission spectroscopy showed the difference in reactive species of air plasma jet between in air and in water. The plasma gun was excited in 20 ml chloroauric acid aqueous solution with a concentration of 1.214 mM. A significant amount of gold nanoparticles were synthesized after 2 min continuous discharge. The plasma gun with these unique features is applicable in plasma medicine, etching, and s-nthesis of nanomaterials.

  9. A hand-held 3D laser scanning with global positioning system of subvoxel precision

    Energy Technology Data Exchange (ETDEWEB)

    Arias, Nestor [GOM, Departamento de Fisica y Geologia, Universidad de Pamplona (Colombia); Meneses, Nestor; Meneses, Jaime [GOTS-CENM, Escuela de Fisica, UIS, Bucaramanga (Colombia); Gharbi, Tijani, E-mail: [Departement D' Optique, FEMTO-ST, 16 Route de Gray, 25030 Besancon (France)


    In this paper we propose a hand-held 3D laser scanner composed of an optical head device to extract 3D local surface information and a stereo vision system with subvoxel precision to measure the position and orientation of the 3D optical head. The optical head is manually scanned over the surface object by the operator. The orientation and position of the 3D optical head is determined by a phase-sensitive method using a 2D regular intensity pattern. This phase reference pattern is rigidly fixed to the optical head and allows their 3D location with subvoxel precision in the observation field of the stereo vision system. The 3D resolution achieved by the stereo vision system is about 33 microns at 1.8 m with an observation field of 60cm x 60cm.

  10. A review of the use of handheld computers in medical nutrition. (United States)

    Holubar, Stefan; Harvey-Banchik, Lillian


    Handheld computers, or personal digital assistants (PDAs), have been used to assist clinicians in medical nutrition since the early 1980s. The term PDA was originally applied to programmable calculators; over time, the capabilities of these devices were expanded to allow for the use of more complicated programs such as databases, spreadsheets, and electronic books. Slowly, the device evolved into what is more commonly thought of as a PDA, that is, a device such as a PalmOS (PalmSource, Inc, Tokyo, Japan) or PocketPC (Microsoft, Redmond, WA) unit. We present a review of the literature about the use of PDAs in medical nutrition, followed by a discussion of the different types of PDAs and mobile technologies that are commercially available. This is followed by a discussion of software applications that are currently available for use by nutrition clinicians, focusing on freeware applications. Finally, future technologies and applications are discussed.

  11. An Enhanced Intelligent Handheld Instrument with Visual Servo Control for 2-DOF Hand Motion Error Compensation

    Directory of Open Access Journals (Sweden)

    Yan Naing Aye


    Full Text Available The intelligent handheld instrument, ITrem2, enhances manual positioning accuracy by cancelling erroneous hand movements and, at the same time, provides automatic micromanipulation functions. Visual data is acquired from a high speed monovision camera attached to the optical surgical microscope and acceleration measurements are acquired from the inertial measurement unit (IMU on board ITrem2. Tremor estimation and canceling is implemented via Band-limited Multiple Fourier Linear Combiner (BMFLC filter. The piezoelectric actuated micromanipulator in ITrem2 generates the 3D motion to compensate erroneous hand motion. Preliminary bench-top 2-DOF experiments have been conducted. The error motions simulated by a motion stage is reduced by 67% for multiple frequency oscillatory motions and 56.16% for pre-conditioned recorded physiological tremor.

  12. Biolistic transfection of neuronal cultures using a hand-held gene gun. (United States)

    O'Brien, John A; Lummis, Sarah C R


    Biolistic transfection is a technique in which subcellular-sized particles coated with DNA are accelerated to high velocity to propel them into cells. This method is applicable to tissues, cells and organelles, and can be used for both in vitro and in vivo transformations; with the right equipment, it is simple, rapid and efficient. Here we provide a detailed protocol for biolistic transfection of plasmids into cultured human embryonic kidney (HEK) 293 cells and organotypic brain slices using a hand-held gene gun. There are three major steps: (i) coating microcarriers with DNA, (ii) transferring the microcarriers into a cartridge to make a 'bullet', and (iii) firing the DNA-coated microcarriers into cells using a pulse of helium gas. The method can be readily adapted to other cell types and tissues. The protocol can be completed in 1-2 h.

  13. Calcium and Phosphorus Detection Using Benchtop Versus Handheld X-ray Fluorescence Spectrometers. (United States)

    Kuzel, Aaron R; Christensen, Angi M; Marvin, Susan M


    Elemental analysis of calcium (Ca) and phosphorus (P) has been shown to be useful in differentiating skeletal and nonskeletal material. X-ray fluorescence spectrometry (XRF) is an attractive, nondestructive technique for forensic anthropologists, and the development of portable XRF instrumentation is promising for field applications. This study examines the performance of handheld XRF instrumentation operated in air compared to a traditional benchtop XRF device that has the ability to control the analysis atmosphere. Both instruments can be used to effectively distinguish skeletal from nonskeletal remains. However, as the measurement atmosphere affects detection levels for calcium and phosphorus, Ca/P ratios obtained from the instruments and analysis conditions were found to differ significantly, with analyses conducted in air showing significantly lower phosphorus detection. Consequently, comparison of Ca/P ratios to conclude skeletal versus nonskeletal origin must be based on data collected under similar analysis conditions.

  14. Mobile applications for handheld devices to screen and randomize acute stroke patients in clinical trials. (United States)

    Qureshi, Ai; Connelly, B; Abbott, Ei; Maland, E; Kim, J; Blake, J


    The availability of internet connectivity and mobile application software used by low-power handheld devices makes smart phones of unique value in time-sensitive clinical trials. Trial-specific applications can be downloaded by investigators from various mobile software distribution platforms or web applications delivered over HTTP. The Antihypertensive Treatment in Acute Cerebral Hemorrhage (ATACH) II investigators in collaboration with MentorMate released the ATACH-II Patient Recruitment mobile application available on iPhone, Android, and Blackberry in 2011. The mobile application provides tools for pre-screening, assessment of eligibility, and randomization of patients. Since the release of ATACH-II mobile application, the CLEAR-IVH (Clot Lysis Evaluating Accelerated Resolution of Intraventricular Hemorrhage) trial investigators have also adopted such a mobile application. The video-conferencing capabilities of the most recent mobile devices open up additional opportunities to involve central coordinating centers in the recruitment process in real time.

  15. Characterization and evaluation of a handheld AC-coupled pulsed photothermal radiometry system (United States)

    Jung, Byungjo; Kim, Chang-Seok; Choi, Bernard; Nelson, J. Stuart


    In laser therapy of port wine stain (PWS) birthmarks, measurement of maximum temperature rise is important to determine the maximum permissible light dose for PWS laser therapy. To measure maximum temperature rise on arbitrary PWS skin site, we developed a handheld pulsed photothermal radiometry (PPTR) system, which overcomes in vivo measurement limitations of bench-top PPTR systems. The developed PPTR system consists of an IR lens, an AC-coupled thermoelectrically cooled IR detector, a laser handpiece holder, and a fixed distance measurement port. With system characterization, experimental results were in good agreement with theoretical calculations. Preliminary results for maximum temperature rise demonstrate the feasibility of the PPTR system for PWS skin characterization in the clinic.

  16. Tracing euxinia by molybdenum concentrations in sediments using handheld X-ray fluorescence spectroscopy (HHXRF)

    DEFF Research Database (Denmark)

    Dahl, Tais W.; Ruhl, Micha; Hammarlund, Emma U.


    Elevated molybdenum (Mo) contents in organic-rich sediments are indicative of deposition from an anoxic and sulfide-rich (euxinic) water-column. This can be used for tracing past euxinic conditions in ancient oceans from sedimentary archives. Conventional analytical detection of elevated molybdenum...... with Mo: 47 ppm and NIST-2702 with Mo: 10 ppm) for analytical control. Analytical precision (1 sigma) after 30, 120, and 300 seconds of measuring time was 4, 2, and 1 ppm, with a respective detection limit of 11, 5, 3 ppm (3 sigma, noise level). The data were accurate to within the given precision (1...... sigma) after a daily calibration to samples covering a range of Mo concentrations from 0 to >30 ppm. Hand-held XRF equipment also allows Mo measurements directly on fresh rock surfaces, both in the field and under laboratory conditions. Rock-samples from a Cambrian drill core closely match ICPMS...

  17. Handheld readout electronics to fully exploit the particle discrimination capabilities of elpasolite scintillators

    Energy Technology Data Exchange (ETDEWEB)

    Budden, B.S., E-mail: [Intelligence and Space Research Division, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Stonehill, L.C.; Warniment, A.; Michel, J.; Storms, S.; Dallmann, N.; Coupland, D.D.S.; Stein, P.; Weller, S.; Borges, L.; Proicou, M.; Duran, G. [Intelligence and Space Research Division, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Kamto, J. [Intelligence and Space Research Division, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Electrical & Computer Engineering Department, Praire View A& M University, Prairie View, TX 77446 (United States)


    A new class of elpasolite scintillators has garnered recent attention due to the ability to perform as simultaneous gamma spectrometers and thermal neutron detectors. Such a dual-mode capability is made possible by pulse-shape discrimination (PSD), whereby the emission waveform profiles of gamma and neutron events are fundamentally unique. To take full advantage of these materials, we have developed the Compact Advanced Readout Electronics for Elpasolites (CAREE). This handheld instrument employs a multi-channel PSD-capable ASIC, custom micro-processor board, front-end electronics, power supplies, and a 2 in. photomultiplier tube for readout of the scintillator. The unit is highly configurable to allow for performance optimization amongst a wide sample of elpasolites which provide PSD in fundamentally different ways. We herein provide an introduction to elpasolites, then describe the motivation for the work, mechanical and electronic design, and preliminary performance results.

  18. A handheld low temperature atmospheric pressure air plasma gun for nanomaterial synthesis in liquid phase

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Shuang; Wang, Kaile; Zuo, Shasha; Liu, Jiahui [Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871 (China); Zhang, Jue, E-mail:; Fang, Jing [Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871 (China); College of Engineering, Peking University, Beijing 100871 (China)


    A handheld low temperature atmospheric pressure air plasma gun based on a dielectric barrier structure with hollow electrodes was proposed. The portable plasma gun with an embedded mini air pump was driven by a 12 V direct voltage battery. The air plasma jet generated from the gun could be touched without a common shock hazard. Besides working in air, the plasma gun can also work in water. The diagnostic result of optical emission spectroscopy showed the difference in reactive species of air plasma jet between in air and in water. The plasma gun was excited in 20 ml chloroauric acid aqueous solution with a concentration of 1.214 mM. A significant amount of gold nanoparticles were synthesized after 2 min continuous discharge. The plasma gun with these unique features is applicable in plasma medicine, etching, and s-nthesis of nanomaterials.

  19. Multiple irradiation sensing of the optical effective attenuation coefficient for spectral correction in handheld OA imaging

    Directory of Open Access Journals (Sweden)

    K. Gerrit Held


    Full Text Available Spectral optoacoustic (OA imaging enables spatially-resolved measurement of blood oxygenation levels, based on the distinct optical absorption spectra of oxygenated and de-oxygenated blood. Wavelength-dependent optical attenuation in the bulk tissue, however, distorts the acquired OA spectrum and thus makes quantitative oxygenation measurements challenging. We demonstrate a correction for this spectral distortion without requiring a priori knowledge of the tissue optical properties, using the concept of multiple irradiation sensing: recording the OA signal amplitude of an absorbing structure (e.g. blood vessel, which serves as an intrinsic fluence detector, as function of irradiation position. This permits the reconstruction of the bulk effective optical attenuation coefficient μeff,λ. If performed at various irradiation wavelengths, a correction for the wavelength-dependent fluence attenuation is achieved, revealing accurate spectral information on the absorbing structures. Phantom studies were performed to show the potential of this technique for handheld clinical combined OA and ultrasound imaging.

  20. Hand-held tools with complex kinematics are efficiently incorporated into movement planning and online control. (United States)

    Baugh, Lee A; Hoe, Erica; Flanagan, J Randall


    Certain hand-held tools alter the mapping between hand motion and motion of the tool end point that must be controlled in order to perform a task. For example, when using a pool cue, the motion of the cue tip is reversed relative to the hand. Previous studies have shown that the time required to initiate a reaching movement (Fernandez-Ruiz J, Wong W, Armstrong IT, Flanagan JR. Behav Brain Res 219: 8-14, 2011), or correct an ongoing reaching movement (Gritsenko V, Kalaska JF. J Neurophysiol 104: 3084-3104, 2010), is prolonged when the mapping between hand motion and motion of a cursor controlled by the hand is reversed. Here we show that these time costs can be significantly reduced when the reversal is instantiated by a virtual hand-held tool. Participants grasped the near end of a virtual tool, consisting of a rod connecting two circles, and moved the end point to displayed targets. In the reversal condition, the rod translated through, and rotated about, a pivot point such that there was a left-right reversal between hand and end point motion. In the nonreversal control, the tool translated with the hand. As expected, when only the two circles were presented, movement initiation and correction times were much longer in the reversal condition. However, when full vision of the tool was provided, the reaction time cost was almost eliminated. These results indicate that tools with complex kinematics can be efficiently incorporated into sensorimotor control mechanisms used in movement planning and online control.

  1. An integrated portable hand-held analyser for real-time isothermal nucleic acid amplification. (United States)

    Smith, Matthew C; Steimle, George; Ivanov, Stan; Holly, Mark; Fries, David P


    A compact hand-held heated fluorometric instrument for performing real-time isothermal nucleic acid amplification and detection is described. The optoelectronic instrument combines a Printed Circuit Board/Micro Electro Mechanical Systems (PCB/MEMS) reaction detection/chamber containing an integrated resistive heater with attached miniature LED light source and photo-detector and a disposable glass waveguide capillary to enable a mini-fluorometer. The fluorometer is fabricated and assembled in planar geometry, rolled into a tubular format and packaged with custom control electronics to form the hand-held reactor. Positive or negative results for each reaction are displayed to the user using an LED interface. Reaction data is stored in FLASH memory for retrieval via an in-built USB connection. Operating on one disposable 3 V lithium battery >12, 60 min reactions can be performed. Maximum dimensions of the system are 150 mm (h) x 48 mm (d) x 40 mm (w), the total instrument weight (with battery) is 140 g. The system produces comparable results to laboratory instrumentation when performing a real-time nucleic acid sequence-based amplification (NASBA) reaction, and also displayed comparable precision, accuracy and resolution to laboratory-based real-time nucleic acid amplification instrumentation. A good linear response (R2 = 0.948) to fluorescein gradients ranging from 0.5 to 10 microM was also obtained from the instrument indicating that it may be utilized for other fluorometric assays. This instrument enables an inexpensive, compact approach to in-field genetic screening, providing results comparable to laboratory equipment with rapid user feedback as to the status of the reaction.


    Energy Technology Data Exchange (ETDEWEB)

    Michael B. Frish; B. David Green; Richard T. Wainner; Francesca Scire-Scappuzzo; Paul Cataldi; Matthew C. Laderer


    This report summarizes work performed by Physical Sciences Inc. (PSI) to advance the state-of-the-art of surveying for leaks of natural gas from transmission and distribution pipelines. The principal project goal was to develop means of deploying on an automotive platform an improved version of the handheld laser-based standoff natural gas leak detector previously developed by PSI and known as the Remote Methane Leak Detector or RMLD. A laser beam which interrogates the air for methane is projected from a spinning turret mounted upon a van. As the van travels forward, the laser beam scans an arc to the front and sides of the van so as to survey across streets and to building walls from a moving vehicle. When excess methane is detected within the arc, an alarm is activated. In this project, we built and tested a prototype Mobile RMLD (MRMLD) intended to provide lateral coverage of 10 m and one lateral scan for every meter of forward motion at forward speeds up to 10 m/s. Using advanced detection algorithms developed as part of this project, the early prototype MRMLD, installed on the back of a truck, readily detected simulated gas leaks of 50 liters per hour. As a supplement to the originally planned project, PSI also participated in a DoE demonstration of several gas leak detection systems at the Rocky Mountain Oilfield Testing Center (RMOTC) during September 2004. Using a handheld RMLD upgraded with the advanced detection algorithms developed in this project, from within a moving vehicle we readily detected leaks created along the 7.4 mile route of a virtual gas transmission pipeline.

  3. The use of handheld radiometry for the identification of stratigraphic characteristics of Paraiba Basin units; A aplicacao da radiometria autoportada na identificacao de caracteristicas estratigraficas nas unidades da Bacia Paraiba

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Ebenezer Moreno de; Villar, Heldio Pereira; Lima, Ricardo de Andrade [Centro Regional de Ciencias Nucleares (CRCN), Recife, PE (Brazil); Lima Filho, Mario [Pernambuco Univ., Recife, PE (Brazil). Dept. de Geologia


    A study on the use of radiometric techniques for the identification of stratigraphic characteristics of Paraiba Basin units was carried out with handheld instrumentation. The area chosen ran from north Pernambuco to south Paraiba. The presence of radioactive material had been previously determined. For this work a portable scintillometer was fixed to the door of a vehicle, on the outside, with the probe directed downwards. Background radiation was measured as 40 cps (counts per second). The scintillometer has an alarm which sounds whenever the measured count rate rises above a pre-established figure, 100 cps in the present case. Monitoring then proceeded manually. In sites where the count rate was much higher than 100 cps, the probe was lowered to the soil surface. Local coordinates were obtained by GPS. Therefore, an isoradioactivity map of the area could be drawn. The comparison between this map and local geological charts showed significant correlation between observed count rates and geologic formations. Low count rates were indicative of the Barreiras formation, whereas the highest rates were obtained for the Gramame formation (with urano-phosphatic lythotypes). It is concluded that handheld radiometry is a useful tool in geological charting, is special in areas where stratigraphic units have been masked by environmental changes and human activities. (author)

  4. D Building FAÇADE Reconstruction Using Handheld Laser Scanning Data (United States)

    Sadeghi, F.; Arefi, H.; Fallah, A.; Hahn, M.


    3D The three dimensional building modelling has been an interesting topic of research for decades and it seems that photogrammetry methods provide the only economic means to acquire truly 3D city data. According to the enormous developments of 3D building reconstruction with several applications such as navigation system, location based services and urban planning, the need to consider the semantic features (such as windows and doors) becomes more essential than ever, and therefore, a 3D model of buildings as block is not any more sufficient. To reconstruct the façade elements completely, we employed the high density point cloud data that obtained from the handheld laser scanner. The advantage of the handheld laser scanner with capability of direct acquisition of very dense 3D point clouds is that there is no need to derive three dimensional data from multi images using structure from motion techniques. This paper presents a grammar-based algorithm for façade reconstruction using handheld laser scanner data. The proposed method is a combination of bottom-up (data driven) and top-down (model driven) methods in which, at first the façade basic elements are extracted in a bottom-up way and then they are served as pre-knowledge for further processing to complete models especially in occluded and incomplete areas. The first step of data driven modelling is using the conditional RANSAC (RANdom SAmple Consensus) algorithm to detect façade plane in point cloud data and remove noisy objects like trees, pedestrians, traffic signs and poles. Then, the façade planes are divided into three depth layers to detect protrusion, indentation and wall points using density histogram. Due to an inappropriate reflection of laser beams from glasses, the windows appear like holes in point cloud data and therefore, can be distinguished and extracted easily from point cloud comparing to the other façade elements. Next step, is rasterizing the indentation layer that holds the windows

  5. Laboratory Tests of a Handheld X-Ray Fluorescence Spectrometer: A Tool for Planetary Exploration (United States)

    Young, K. E.; Evans, C. A.; Hodges, K.


    Maximizing the science return from a mission to another planetary surface involves the integration of science objectives with deployable technologies that enable the collection of data and samples. For long duration manned missions, it is likely that more samples will be collected than can be returned to Earth due to mass limits. A niche exists for technologies that help prioritize samples for return, provide data for future sample handling and curation, and characterization for samples that are not returned to Earth. To fill this niche, hardware and protocols for field instruments are currently being developed and evaluated at NASA Johnson Space Center and Arizona State University. Our goal is to develop an easily used, environmentally isolated facility as part of the astronaut surface habitat for preliminary sample characterization and down-selection. NASA has constructed a prototype, GeoLab, as a testbed for evaluating the scientific applicability and operational considerations of various analytical instruments. One instrument under evaluation is a small, portable x-ray fluorescence (XRF) spectrometer that can be also be used by astronaut explorers as part of their field gear while on scientific sorties, or on robotic field assistants. We report on preliminary usability tests for commercially available handheld XRF instruments. These instruments collect data by contacting the surface of a rock or sediment sample with an 8 mm-wide sensor window. Within 60 seconds, the devices can provide relatively precise data on the abundance of major and trace elements heavier than Na. Lab-based handheld XRF analyses of terrestrial and lunar samples, compared with those made with full-scale laboratory XRF systems, show good correlation, but we continue to investigate potential sources of error and the need for careful calibration with standards of known composition. Specifically, we use a suite of five terrestrial and five lunar basalts, all well characterized by conventional

  6. Rapid prediction of total petroleum hydrocarbons in soil using a hand-held mid-infrared field instrument. (United States)

    Webster, Grant T; Soriano-Disla, José M; Kirk, Joel; Janik, Leslie J; Forrester, Sean T; McLaughlin, Mike J; Stewart, Richard J


    This manuscript reports on the performance of a hand-held diffuse reflectance (mid)-infrared Fourier transform (DRIFT) spectrometer for the prediction of total petroleum hydrocarbons (TPH) in three different diesel-contaminated soils. These soils include: a carbonate dominated clay, a kaolinite dominated clay and a loam from Padova Italy, north Western Australia and southern Nigeria, respectively. Soils were analysed for TPH concentration using a standard laboratory methods and scanned in DRIFT mode with the hand-held spectrometer to determine TPH calibration models. Successful partial least square regression (PLSR) predictions, with coefficient of determination (R(2)) ~0.99 and root mean square error (RMSE) held mid-infrared instrument can accurately detect TPH across different soil types and concentrations, which paves the way for a variety of applications in the field.

  7. Hand-held analyser based on microchip electrophoresis with contactless conductivity detection for measurement of chemical warfare agent degradation products (United States)

    Duran, Karolina-Petkovic; Zhu, Yonggang; Chen, Chuanpin; Swallow, Anthony; Stewart, Robert; Hoobin, Pam; Leech, Patrick; Ovenden, Simon


    This paper reports on the development of a hand-held device for on-site detection of organophosphonate nerve agent degradation products. This field-deployable analyzer relies on efficient microchip electrophoresis separation of alkyl methylphosphonic acids and their sensitive contactless conductivity detection. Miniaturized, low-powered design is coupled with promising analytical performance for separating the breakdown products of chemical warfare agents such as Soman, Sarin and VX . The detector has a detection limit of about 10 μg/mL and has a good linear response in the range 10-300 μg/mL concentration range. Applicability to environmental samples is demonstrated .The new hand-held analyzer offers great promise for converting conventional ion chromatography or capillary electrophoresis sophisticated systems into a portable forensic laboratory for faster, simpler and more reliable on-site screening.

  8. Guiding Brain Tumor Resection Using Surface-Enhanced Raman Scattering Nanoparticles and a Hand-Held Raman Scanner


    Karabeber, Hazem; Huang, Ruimin; Iacono, Pasquale; Samii, Jason M.; Pitter, Ken; Holland, Eric C.; Kircher, Moritz F.


    The current difficulty in visualizing the true extent of malignant brain tumors during surgical resection represents one of the major reasons for the poor prognosis of brain tumor patients. Here, we evaluated the ability of a hand-held Raman scanner, guided by surface-enhanced Raman scattering (SERS) nanoparticles, to identify the microscopic tumor extent in a genetically engineered RCAS/tv-a glioblastoma mouse model. In a simulated intraoperative scenario, we tested both a static Raman imagi...

  9. Torque Removal Evaluation of Screw in One-Piece and Two-Piece Abutments Tightened with a Handheld screwdriver

    Directory of Open Access Journals (Sweden)

    Jalil Ghanbarzadeh


    Full Text Available Introduction: Some clinicians use a handheld screw driver instead of a torque wrench to definitively tighten abutment screws. The aim of this study was to compare the removal torque of one-piece and two-piece abutments tightened with a handheld driver and a torque control ratchet. Methods: 40 ITI implants were placed in acrylic blocks and divided into 4 groups. In groups one and two, 10 ITI one-piece abutments (Solid® and in groups three and four, 10 ITI two-piece abutments (Synocta® were placed on the implants. In groups one and three abutments were tightened by 5 experienced males and 5 experienced females using a handheld driver. In groups two and four abutments were tightened using a torque wrench with torque values of 10, 20 and 35 Insertion torque and removal torque values of the abutments were measured with a digital torque meter. Results: The insertion torque values (ITVs of males in both abutments were significantly higher than those of females. ITVs in both Solid® and Synocta® abutments tightened with a handheld screwdriver were similar to the torque of 20 in the torque wrench. Removal torque values (RTVs of solid® abutments were higher than those of synocta® abutments. Conclusion: The one- piece abutments (solid® showed higher RTVs than the two-piece abutments (synocta®. Hand driver does not produce sufficient preload force for the final tightening of the abutment

  10. In vivo evaluation of a novel, wrist-mounted arterial pressure sensing device versus the traditional hand-held tonometer. (United States)

    Vardoulis, Orestis; Saponas, T Scott; Morris, Dan; Villar, Nicolas; Smith, Greg; Patel, Shwetak; Tan, Desney


    Although hemodynamic parameters can be assessed non-invasively, state-of-the-art non-invasive systems generally require an expert operator and are not applicable for ambulatory measurements. These limitations have restricted our understanding of the continuous behavior of hemodynamic parameters. In this manuscript, we introduce a novel wrist-mounted device that incorporates an array of pressure sensors which can be used to extract arterial waveforms and relevant pulse wave analysis biomarkers. In vivo evaluation is performed with Bland-Altman analysis to compare the novel sensor to a gold-standard hand-held tonometer by assessing their reproducibility and agreement in peripheral augmentation index (AIx) estimation at the radial artery. Arterial waves from 28 randomly selected participants were recorded in a controlled environment. Initially we assess the reproducibility of AIx results for both devices. The intra-class correlation coefficient (ICC) and mean difference ± SD were [0.913, 0.033±0.048] and [0.859, 0.039±0.076] for the hand-held and the wrist-mounted tonometer respectively. We then show that the AIx values derived from the novel tonometer have good agreement, accuracy, and precision when compared against the AIx values derived from the reference hand-held tonometer (ICC 0.927, mean difference 0.026±0.049). In conclusion, we have presented evidence that the new wrist-mounted arterial pressure sensor records arterial waveforms that can be processed to yield AIx values that are in good agreement with its traditional hand-held counterpart.

  11. Vision-Based Control of a Handheld Surgical Micromanipulator with Virtual Fixtures (United States)

    Becker, Brian C.; MacLachlan, Robert A.; Lobes, Louis A.; Hager, Gregory D.; Riviere, Cameron N.


    Performing micromanipulation and delicate operations in submillimeter workspaces is difficult because of destabilizing tremor and imprecise targeting. Accurate micromanipulation is especially important for microsurgical procedures, such as vitreoretinal surgery, to maximize successful outcomes and minimize collateral damage. Robotic aid combined with filtering techniques that suppress tremor frequency bands increases performance; however, if knowledge of the operator’s goals is available, virtual fixtures have been shown to further improve performance. In this paper, we derive a virtual fixture framework for active handheld micromanipulators that is based on high-bandwidth position measurements rather than forces applied to a robot handle. For applicability in surgical environments, the fixtures are generated in real-time from microscope video during the procedure. Additionally, we develop motion scaling behavior around virtual fixtures as a simple and direct extension to the proposed framework. We demonstrate that virtual fixtures significantly outperform tremor cancellation algorithms on a set of synthetic tracing tasks (p < 0.05). In more medically relevant experiments of vein tracing and membrane peeling in eye phantoms, virtual fixtures can significantly reduce both positioning error and forces applied to tissue (p < 0.05). PMID:24639624

  12. 3D indoor modeling using a hand-held embedded system with multiple laser range scanners (United States)

    Hu, Shaoxing; Wang, Duhu; Xu, Shike


    Accurate three-dimensional perception is a key technology for many engineering applications, including mobile mapping, obstacle detection and virtual reality. In this article, we present a hand-held embedded system designed for constructing 3D representation of structured indoor environments. Different from traditional vehicle-borne mobile mapping methods, the system presented here is capable of efficiently acquiring 3D data while an operator carrying the device traverses through the site. It consists of a simultaneous localization and mapping(SLAM) module, a 3D attitude estimate module and a point cloud processing module. The SLAM is based on a scan matching approach using a modern LIDAR system, and the 3D attitude estimate is generated by a navigation filter using inertial sensors. The hardware comprises three 2D time-flight laser range finders and an inertial measurement unit(IMU). All the sensors are rigidly mounted on a body frame. The algorithms are developed on the frame of robot operating system(ROS). The 3D model is constructed using the point cloud library(PCL). Multiple datasets have shown robust performance of the presented system in indoor scenarios.

  13. Handheld probe integrating laser diode and ultrasound transducer array for ultrasound/photoacoustic dual modality imaging. (United States)

    Daoudi, K; van den Berg, P J; Rabot, O; Kohl, A; Tisserand, S; Brands, P; Steenbergen, W


    Ultrasound and photoacoustics can be utilized as complementary imaging techniques to improve clinical diagnoses. Photoacoustics provides optical contrast and functional information while ultrasound provides structural and anatomical information. As of yet, photoacoustic imaging uses large and expensive systems, which limits their clinical application and makes the combination costly and impracticable. In this work we present and evaluate a compact and ergonomically designed handheld probe, connected to a portable ultrasound system for inexpensive, real-time dual-modality ultrasound/photoacoustic imaging. The probe integrates an ultrasound transducer array and a highly efficient diode stack laser emitting 130 ns pulses at 805 nm wavelength and a pulse energy of 0.56 mJ, with a high pulse repetition frequency of up to 10 kHz. The diodes are driven by a customized laser driver, which can be triggered externally with a high temporal stability necessary to synchronize the ultrasound detection and laser pulsing. The emitted beam is collimated with cylindrical micro-lenses and shaped using a diffractive optical element, delivering a homogenized rectangular light intensity distribution. The system performance was tested in vitro and in vivo by imaging a human finger joint.

  14. Aortic atherosclerotic plaque detection using a multiwavelength handheld photoacoustic imaging system (United States)

    Hirano, Susumu; Namita, Takeshi; Kondo, Kengo; Yamakawa, Makoto; Shiina, Tsuyoshi


    Patients affected by diseases caused by arteriosclerosis are increasing. Atherosclerosis, which is becoming an especially difficult health problem, forms plaques from lipids such as cholesterol located in walls of the aorta, cerebral artery, and coronary artery. Because lipid-rich plaques are vulnerable and because arterial rupture causes acute vascular occlusion, early detection is crucially important to prevent plaque growth and rupture. Ultrasound systems can detect plaques but cannot discriminate between vulnerable and equable plaques. To evaluate plaques non-invasively and easily, we developed a handheld photoacoustic imaging device. Its usefulness was verified in phantom experiments with a bovine aorta in which mimic plaque had been embedded. Photoacoustic images taken at wavelengths that produce high light absorbance by lipids show strong photoacoustic signals from the boundary of the mimic plaque. Results confirmed that our system can evaluate plaque properties by analysis with the photoacoustic spectrum. The effects of surrounding tissues and tissue components on plaque evaluation were investigated using a layered phantom. The mimic plaque located under a 6 mm blood layer was also evaluated. Results of these analyses demonstrate the system's usefulness.

  15. Noise surveys of hand-held pneumatic rock drills in Hong Kong. (United States)

    Tah-Chew, T; Keung, W C


    A study of the noise generated by hand-held pneumatic rock drills at 15 road works locations in Hong Kong was conducted in 1989. The locations of road construction works were identified over one week period. Sound pressure levels (SPL) and band frequency analysis were measured with the integrated sound level meter at the level of the operator's ears. The sound levels for all 15 operators exceeded the local statutory limit of 90 dBA. The average sound level was 107.4 dBA and the corresponding continuous equivalent level adjusted to 8 hours or L eq (8h) was 104.8 dBA. The sound levels for the octave frequencies from 125 Hertz to 8000 Hertz were all in excess of 90 dBA. Estimates of the risk of developing hearing impairment for conversation speech among the operators were 18% and 42% after 5 and 10 years of exposure, respectively. Although there is adequate statutory control to restrict and reduce the hazards caused by noise at road construction works to the workers and to the public at large, no noise control measures were noted at the work sites and none of the operators used hearing protection. This situation was compounded by the short-term nature of road works and the high mobility of the operators.

  16. Evaluation of Handheld Assays for the Detection of Ricin and Staphylococcal Enterotoxin B in Disinfected Waters

    Directory of Open Access Journals (Sweden)

    Mary Margaret Wade


    Full Text Available Development of a rapid field test is needed capable of determining if field supplies of water are safe to drink by the warfighter during a military operation. The present study sought to assess the effectiveness of handheld assays (HHAs in detecting ricin and Staphylococcal Enterotoxin B (SEB in water. Performance of HHAs was evaluated in formulated tap water with and without chlorine, reverse osmosis water (RO with chlorine, and RO with bromine. Each matrix was prepared, spiked with ricin or SEB at multiple concentrations, and then loaded onto HHAs. HHAs were allowed to develop and then read visually. Limits of detection (LOD were determined for all HHAs in each water type. Both ricin and SEB were detected by HHAs in formulated tap water at or below the suggested health effect levels of 455 ng/mL and 4.55 ng/mL, respectively. However, in brominated or chlorinated waters, LODs for SEB increased to approximately 2,500 ng/mL. LODs for ricin increased in chlorinated water, but still remained below the suggested health effect level. In brominated water, the LOD for ricin increased to approximately 2,500 ng/mL. In conclusion, the HHAs tested were less effective at detecting ricin and SEB in disinfected water, as currently configured.

  17. Design of a Handheld Pseudo Random Coded UWB Radar for Human Sensing

    Directory of Open Access Journals (Sweden)

    Xia Zheng-huan


    Full Text Available This paper presents the design of a handheld pseudo random coded Ultra-WideBand (UWB radar for human sensing. The main tasks of the radar are to track the moving human object and extract the human respiratory frequency. In order to achieve perfect penetrability and good range resolution, m sequence with a carrier of 800 MHz is chosen as the transmitting signal. The modulated m-sequence can be generated directly by the high-speed DAC and FPGA to reduce the size of the radar system, and the mean power of the transmitting signal is 5 dBm. The receiver has two receiving channels based on hybrid sampling, the first receiving channel is to sample the reference signal and the second receiving channel is to obtain the radar echo. The real-time pulse compression is computed in parallel with a group of on-chip DSP48E slices in FPGA to improve the scanning rate of the radar system. Additionally, the algorithms of moving target tracking and life detection are implemented using Intel’s micro-processor, and the detection results are sent to the micro displayer fixed on the helmet. The experimental results show that the moving target located at less than 16 m far away from the wall can be tracked, and the respiratory frequency of the static human at less than 14 m far away from the wall can be extracted.

  18. Handheld lasers allow efficient detection of fluorescent marked organisms in the field. (United States)

    Rice, Kevin B; Fleischer, Shelby J; De Moraes, Consuelo M; Mescher, Mark C; Tooker, John F; Gish, Moshe


    Marking organisms with fluorescent dyes and powders is a common technique used in ecological field studies that monitor movement of organisms to examine life history traits, behaviors, and population dynamics. External fluorescent marking is relatively inexpensive and can be readily employed to quickly mark large numbers of individuals; however, the ability to detect marked organisms in the field at night has been hampered by the limited detection distances provided by portable fluorescent ultraviolet lamps. In recent years, significant advances in LED lamp and laser technology have led to development of powerful, low-cost ultraviolet light sources. In this study, we evaluate the potential of these new technologies to improve detection of fluorescent-marked organisms in the field and to create new possibilities for tracking marked organisms in visually challenging environments such as tree canopies and aquatic habitats. Using handheld lasers, we document a method that provides a fivefold increase in detection distance over previously available technologies. This method allows easy scouting of tree canopies (from the ground), as well as shallow aquatic systems. This novel detection method for fluorescent-marked organisms thus promises to significantly enhance the use of fluorescent marking as a non-destructive technique for tracking organisms in natural environments, facilitating field studies that aim to document otherwise inaccessible aspects of the movement, behavior, and population dynamics of study organisms, including species with significant economic impacts or relevance for ecology and human health.

  19. Handheld imaging photonic crystal biosensor for multiplexed, label-free protein detection. (United States)

    Jahns, Sabrina; Bräu, Marion; Meyer, Björn-Ole; Karrock, Torben; Gutekunst, Sören B; Blohm, Lars; Selhuber-Unkel, Christine; Buhmann, Raymund; Nazirizadeh, Yousef; Gerken, Martina


    We present a handheld biosensor system for the label-free and specific multiplexed detection of several biomarkers employing a spectrometer-free imaging measurement system. A photonic crystal surface functionalized with multiple specific ligands forms the optical transducer. The photonic crystal slab is fabricated on a glass substrate by replicating a periodic grating master stamp with a period of 370 nm into a photoresist via nanoimprint lithography and deposition of a 70-nm titanium dioxide layer. Capture molecules are coupled covalently and drop-wise to the photonic crystal surface. With a simple camera and imaging optics the surface-normal transmission is detected. In the transmission spectrum guided-mode resonances are observed that shift due to protein binding. This shift is observed as an intensity change in the green color channel of the camera. Non-functionalized image sections are used for continuous elimination of background drift. In a first experiment we demonstrate the specific and time-resolved detection of 90.0 nm CD40 ligand antibody, 90.0 nM EGF antibody, and 500 nM streptavidin in parallel on one sensor chip. In a second experiment, aptamers with two different spacer lengths are used as receptor. The binding kinetics with association and dissociation of 250 nM thrombin and regeneration of the sensor surface with acidic tris-HCl-buffer (pH 5.0) is presented for two measurement cycles.

  20. Hand-Held Instrument Fights Acne, Tops Over-the-Counter Market (United States)


    Tyrell Inc., a Houston-based medical technologies company, was able to access engineering support in redesigning a heating element for a hand-held acne-fighting device through SATOP, NASA's Space Alliance Technology Outreach Program. SATOP put Tyrell in contact with The Boeing Company, which assessed the design and made several major contributions. The product, named Zeno, is now the highest selling over-the-counter medical device for the treatment of acne, and in 2006, Zeno was named the "SATOP Texas, Success Story of the Year." Zeno employs proprietary ClearPoint technology to provide relief of mild to moderate inflammatory acne by delivering a precisely controlled low-level dosage of heat to the blemish, causing the bacteria at the root of more than 90 percent of acne to self-destruct. Within its first year on the market, Zeno was cited by various publications for several awards, including Allure's 2005 "Best of Beauty," Marie Claire's "10 Best Gadgets for Girls," and Popular Science's 2005 "Best of What's New." A variation of the Zeno for use in treating herpetic lesions such as cold sores, by killing the virus that causes them, is currently undergoing FDA trials.

  1. Evaluation of the Roche CoaguChek XS handheld coagulation analyzer in a cardiac outpatient clinic. (United States)

    Nam, Myung-Hyun; Roh, Kyoung Ho; Pak, Hui-Nam; Lee, Chang Kyu; Kim, Young-Hoon; Lee, Kap No; Cho, Yunjung


    This study evaluated the performance of a handheld coagulation analyzer for measurements of capillary blood specimens of 93 outpatient cardiology patients with atrial fibrillation who were receiving oral anti-coagulant therapy. The international normalized ratio (INR) results of the CoaguChek XS system (Roche Diagnostics) were compared with those obtained in the central laboratory with citrated venous blood specimens using the ACL9000 coagulation analyzer (Instrumentation Laboratory). The INR results for prothrombin time by the CoaguChek XS analyzer were closely correlated with the central laboratory's results in the INR range of 0.96 approximately 8.53 (r = 0.964). A statistically significant difference was noted between 2 lots of test strips, but the difference was miniscule (mean +/- 95% confidence interval: 0.04+/-0.02). The CV of 8 replicate assays with the CoaguChek XS for a blood specimen with high INR value (INR=3.9) was 1.4%; for a blood specimen with medium INR value (INR=1.3), the CV of 8 replicate assays was XS analyzer is precise and reliable for assessment of INR results at clinically significant ranges in cardiac outpatients.

  2. A handheld SPIO-based sentinel lymph node mapping device using differential magnetometry (United States)

    Waanders, S.; Visscher, M.; Wildeboer, R. R.; Oderkerk, T. O. B.; Krooshoop, H. J. G.; ten Haken, B.


    Sentinel lymph node biopsy has become a staple tool in the diagnosis of breast cancer. By replacing the morbidity-plagued axillary node clearance with removing only those nodes most likely to contain metastases, it has greatly improved the quality of life of many breast cancer patients. However, due to the use of ionizing radiation emitted by the technetium-based tracer material, the current sentinel lymph node biopsy has serious drawbacks. Most urgently, the reliance on radioisotopes limits the application of this procedure to small parts of the developed world, and it imposes restrictions on patient planning and hospital logistics. Magnetic alternatives have been tested in recent years, but all have their own drawbacks, mostly related to interference from metallic instruments and electromagnetic noise coming from the human body. In this paper, we demonstrate an alternative approach that utilizes the unique nonlinear magnetic properties of superparamagnetic iron oxide nanoparticles to eliminate the drawbacks of both the traditional gamma-radiation centered approach and the novel magnetic techniques pioneered by others. Contrary to many other nonlinear magnetic approaches however, field amplitudes are limited to 5 mT, which enables handheld operation without additional cooling. We show that excellent mass sensitivity can be obtained without the need for external re-balancing of the probe to negate any influences from the human body. Additionally, we show how this approach can be used to suppress artefacts resulting from the presence of metallic instruments, which are a significant dealbreaker when using conventional magnetometry-based approaches.

  3. Ultra-low power HOT MCT grown by MOVPE for handheld applications (United States)

    Pillans, Luke; Baker, Ian; McEwen, R. Kennedy


    In 2012 Selex ES demonstrated High Operating Temperature (HOT) MCT detectors with 5μm cut-off wavelength and f/4 aperture operating at temperatures above 200K. These detectors are grown by Metal Organic Vapour Phase Epitaxy (MOVPE) which enables fine control over the photo-diode structure. Since 2012 Selex has created two further generations of MOVPE HOT MCT, progressively improving operability and yield. This paper presents performance data for Selex's third generation of HOT MCT technology and describes the improvements to the diode design and materials processing that have enabled these advances. A parallel program has developed miniature Dewars with lower heatload and reduced manufacturing costs. When integrated with the latest generation of miniature linear cryo-engines the required cooler power is reduced to the region of 1W at temperatures of 200K. This paper will present example imagery from a detector operating with <1 Watt cooler input power. The combination of third generation HOT MCT, high efficiency Dewars and miniature linear coolers will allow a drastic reduction in SWAP-C for long range hand-held thermal imagers.

  4. On-chip lysis of mammalian cells through a handheld corona device. (United States)

    Escobedo, C; Bürgel, S C; Kemmerling, S; Sauter, N; Braun, T; Hierlemann, A


    On-chip lysis is required in many lab-on-chip applications involving cell studies. In these applications, the complete disruption of the cellular membrane and a high lysis yield is essential. Here, we present a novel approach to lyse cells on-chip through the application of electric discharges from a corona handheld device. The method only requires a microfluidic chip and a low-cost corona device. We demonstrate the effective lysis of BHK and eGFP HCT 116 cells in the sub-second time range using an embedded microelectrode. We also show cell lysis of non-adherent K562 leukemia cells without the use of an electrode in the chip. Cell lysis has been assessed through the use of bright-field microscopy, high-speed imaging and cell-viability fluorescence probes. The experimental results show effective cell lysis without any bubble formation or significant heating. Due to the simplicity of both the components involved and the lysis procedure, this technique offers an inexpensive lysis option with the potential for integration into lab-on-a-chip devices.

  5. Handheld cellular phones restrict head movements and range of visual regard. (United States)

    Thumser, Zachary C; Stahl, John S


    Numerous studies have reported the ability of mobile phones to distract users and thereby degrade performance of concurrent tasks. Less is known about whether the phone-holding posture can itself influence concurrent motor activities. Horizontal eye movements are often coordinated with head movements, particularly when the amplitude of the gaze shift is large. Holding a phone to one ear has been shown to restrict the range of spontaneously generated head movements. In order to determine whether the phone-holding posture also influences gaze, we recorded eye and head movements as volunteers looked about themselves spontaneously. Holding the phone to the ear narrowed the range of gaze, principally in subjects who exhibit a strong propensity to move the head with the eyes. We argue that visual exploration may be influenced by the balance between costs and benefits of turning the head, with the phone-holding posture increasing the costs. The effects on gaze would be seen most clearly in subjects who have a higher predilection for coupling eye and head movements. Conversely, this effect would be minimal if tested in tasks that rarely elicit head movements in the specific subjects being tested. The results emphasize the close coordination between eye and head movements, and have implications for the design of ergonomic studies comparing the effects of handheld vs. hands-free mobile phones on performance of specific tasks, such as driving.

  6. Improvement of registration accuracy of a handheld augmented reality system for urban landscape simulation

    Directory of Open Access Journals (Sweden)

    Tomohiro Fukuda


    Full Text Available The need for visual landscape assessment in large-scale projects for the evaluation of the effects of a particular project on the surrounding landscape has grown in recent years. Augmented reality (AR has been considered for use as a landscape simulation system in which a landscape assessment object created by 3D models is included in the present surroundings. With the use of this system, the time and the cost needed to perform a 3DCG modeling of present surroundings, which is a major issue in virtual reality, are drastically reduced. This research presents the development of a 3D map-oriented handheld AR system that achieves geometric consistency using a 3D map to obtain position data instead of GPS, which has low position information accuracy, particularly in urban areas. The new system also features a gyroscope sensor to obtain posture data and a video camera to capture live video of the present surroundings. All these components are mounted in a smartphone and can be used for urban landscape assessment. Registration accuracy is evaluated to simulate an urban landscape from a short- to a long-range scale. The latter involves a distance of approximately 2000 m. The developed AR system enables users to simulate a landscape from multiple and long-distance viewpoints simultaneously and to walk around the viewpoint fields using only a smartphone. This result is the tolerance level of landscape assessment. In conclusion, the proposed method is evaluated as feasible and effective.

  7. Detection of fecal contamination on beef meat surfaces using handheld fluorescence imaging device (HFID) (United States)

    Oh, Mirae; Lee, Hoonsoo; Cho, Hyunjeong; Moon, Sang-Ho; Kim, Eun-Kyung; Kim, Moon S.


    Current meat inspection in slaughter plants, for food safety and quality attributes including potential fecal contamination, is conducted through by visual examination human inspectors. A handheld fluorescence-based imaging device (HFID) was developed to be an assistive tool for human inspectors by highlighting contaminated food and food contact surfaces on a display monitor. It can be used under ambient lighting conditions in food processing plants. Critical components of the imaging device includes four 405-nm 10-W LEDs for fluorescence excitation, a charge-coupled device (CCD) camera, optical filter (670 nm used for this study), and Wi-Fi transmitter for broadcasting real-time video/images to monitoring devices such as smartphone and tablet. This study aimed to investigate the effectiveness of HFID in enhancing visual detection of fecal contamination on red meat, fat, and bone surfaces of beef under varying ambient luminous intensities (0, 10, 30, 50 and 70 foot-candles). Overall, diluted feces on fat, red meat and bone areas of beef surfaces were detectable in the 670-nm single-band fluorescence images when using the HFID under 0 to 50 foot-candle ambient lighting.

  8. Hazardous metals in vintage plastic toys measured by a handheld X-ray fluorescence spectrometer. (United States)

    Miller, Gillian Zaharias; Harris, Zoe E


    Over 100 plastic toys from the 1970s and 1980s, both polyvinyl chloride ("vinyl") and nonvinyl, were analyzed in the study described here using a handheld X-ray fluorescence spectrometer to quantify hazardous metal content. A sampling of recent vinyl toys was also tested. The majority of nonvinyl samples were Fisher Price brand toys. The vinyl toys consisted largely of Barbie dolls and other dolls. Overall, lead or cadmium was found in 67% of vintage plastic toys, frequently at concentrations exceeding current U.S. and European limits. Arsenic was detected at levels of concern in 16% of the samples. In the nonvinyl toys, heavy metal content was found to correlate with certain colors of plastic. The likely sources of the detected metals are discussed. None of the contemporary vinyl toys contained detectable cadmium, lead, or arsenic. Given that vintage toys remain in widespread use by children in homes and other locations, the results illuminate a potential source of heavy metal exposure for children.

  9. Developing handheld real time multispectral imager to clinically detect erythema in darkly pigmented skin (United States)

    Kong, Linghua; Sprigle, Stephen; Yi, Dingrong; Wang, Fengtao; Wang, Chao; Liu, Fuhan


    Pressure ulcers have been identified as a public health concern by the US government through the Healthy People 2010 initiative and the National Quality Forum (NQF). Currently, no tools are available to assist clinicians in erythema, i.e. the early stage pressure ulcer detection. The results from our previous research (supported by NIH grant) indicate that erythema in different skin tones can be identified using a set of wavelengths 540, 577, 650 and 970nm. This paper will report our recent work which is developing a handheld, point-of-care, clinicallyviable and affordable, real time multispectral imager to detect erythema in persons with darkly pigmented skin. Instead of using traditional filters, e.g. filter wheels, generalized Lyot filter, electrical tunable filter or the methods of dispersing light, e.g. optic-acoustic crystal, a novel custom filter mosaic has been successfully designed and fabricated using lithography and vacuum multi layer film technologies. The filter has been integrated with CMOS and CCD sensors. The filter incorporates four or more different wavelengths within the visual to nearinfrared range each having a narrow bandwidth of 30nm or less. Single wavelength area is chosen as 20.8μx 20.8μ. The filter can be deposited on regular optical glass as substrate or directly on a CMOS and CCD imaging sensor. This design permits a multi-spectral image to be acquired in a single exposure, thereby providing overwhelming convenience in multi spectral imaging acquisition.

  10. The Distribution of Elements in 48 Canine Compact Bone Types Using Handheld X-Ray Fluorescence. (United States)

    Nganvongpanit, Korakot; Buddhachat, Kittisak; Piboon, Promporn; Klinhom, Sarisa


    A major question when we talk about the elements in the bone is whether all bones contain the same elements. To answer this question, this study was designed for determination of the elemental levels in 48 various canine compact bones using handheld X-ray fluorescence technique. From a total of 26 elements that could be detected, only 13 elements were found in all 48 bones. The sternum and os penis were significantly different from the other bones in that they contained the highest number of elements. The ratio of Ca and P was significantly different when comparing certain bones: there was a higher Ca/P ratio in the patella (right), calcaneus (right and left), and sternum compared with a lower ratio in the radius (left), rib (left), phalanx (left forelimb), and carpus (left). These results are the first to demonstrate that different types of bones have different elemental profiles, even for major elements such as Ca and P. Moreover, the Ca/P ratio was also different between bone types. This data is important for the selection of bones appropriate to the element studied. In addition, the results proved that the elements were not equally distributed in every bone in the body.

  11. Handheld low-frequency phased array near-infrared (NIR) breast cancer localizer (United States)

    Liu, Qian; Chen, Yu; Luo, Qingming


    A system for rapid and precise localization of breast cancer using low frequency phased array near-infrared technique has been developed. In this system, in-phase and out-of-phase of sine-wave signals at 3 kHz modulate two light emitting diode (LED) sources respectively. And amplitude cancellation of two photon density waves will occur in the silicon-detector at the mid-plane of two sources reference. Cancellation signal is displayed by an embedded amplitude and phase detector and is displayed acoustically. The whole system is pocket-size, handheld with the dimension of 6.0cm×5.0cm×2.5cm and the weight is 140g. Experiments with phantom and animals show that the system can provide real time detection and localization of small hidden absorbing-fluorescent objects inside the highly scattering medium at the depth of 2cm with high accuracy of +/-1 ~ 2mm. The limit of object detection with 20 mA LED current is 1cm and with 40 mA is 2cm. The potential application is that it can be used for early breast cancer detection as a convenient self-examination device.

  12. High-resolution handheld rigid endomicroscope based on full-field optical coherence tomography (United States)

    Benoit a la Guillaume, Emilie; Martins, Franck; Boccara, Claude; Harms, Fabrice


    Full-field optical coherence tomography (FF-OCT) is a powerful tool for nondestructive assessment of biological tissue, i.e., for the structural examination of tissue in depth at a cellular resolution. Mostly known as a microscopy device for ex vivo analysis, FF-OCT has also been adapted to endoscopy setups since it shows good potential for in situ cancer diagnosis and biopsy guidance. Nevertheless, all the attempts to perform endoscopic FF-OCT imaging did not go beyond lab setups. We describe here, to the best of our knowledge, the first handheld FF-OCT endoscope based on a tandem interferometry assembly using incoherent illumination. A common-path passive imaging interferometer at the tip of an optical probe makes it robust and insensitive to environmental perturbations, and a low finesse Fabry-Perot processing interferometer guarantees a compact system. A good resolution (2.7 μm transverse and 6 μm axial) is maintained through the long distance, small diameter relay optics of the probe, and a good signal-to-noise ratio is achieved in a limited 100 ms acquisition time. High-resolution images and a movie of a rat brain slice have been recorded by moving the contact endoscope over the surface of the sample, allowing for tissue microscopic exploration at 20 μm under the surface. These promising ex vivo results open new perspectives for in vivo imaging of biological tissue, in particular, in the field of cancer and surgical margin assessment.

  13. Murine fundus fluorescein angiography: An alternative approach using a handheld camera. (United States)

    Ehrenberg, Moshe; Ehrenberg, Scott; Schwob, Ouri; Benny, Ofra


    In today's modern pharmacologic approach to treating sight-threatening retinal vascular disorders, there is an increasing demand for a compact, mobile, lightweight and cost-effective fluorescein fundus camera to document the effects of antiangiogenic drugs on laser-induced choroidal neovascularization (CNV) in mice and other experimental animals. We have adapted the use of the Kowa Genesis Df Camera to perform Fundus Fluorescein Angiography (FFA) in mice. The 1 kg, 28 cm high camera has built-in barrier and exciter filters to allow digital FFA recording to a Compact Flash memory card. Furthermore, this handheld unit has a steady Indirect Lens Holder that firmly attaches to the main unit, that securely holds a 90 diopter lens in position, in order to facilitate appropriate focus and stability, for photographing the delicate central murine fundus. This easily portable fundus fluorescein camera can effectively record exceptional central retinal vascular detail in murine laser-induced CNV, while readily allowing the investigator to adjust the camera's position according to the variable head and eye movements that can randomly occur while the mouse is optimally anesthetized. This movable image recording device, with efficiencies of space, time, cost, energy and personnel, has enabled us to accurately document the alterations in the central choroidal and retinal vasculature following induction of CNV, implemented by argon-green laser photocoagulation and disruption of Bruch's Membrane, in the experimental murine model of exudative macular degeneration.

  14. 手持产品人机舒适度创新实验设计%An innovation human engineering experiment design of comfort of handheld products

    Institute of Scientific and Technical Information of China (English)

    张祖耀; 朱媛; 夏芒


    In view of the problems in human engineering experiment teaching and promotion of comfort of handheld products,this article, by introducing the Kansei Engineering design, designs a human engineering experiment teaching method based on ration, data and operation. , and further states a clear process and its innova-tiveness and practicability combined with bus handle case, which provides references for promoting the ergonomics teaching quality and top-notch talents training.%针对目前工业设计人机工程学实验教学中存在的问题,通过引入感性工学的设计方法,针对手持产品的舒适度,设计了一种基于理性、数据、可操作的产品人机创新实验与教学方法,并结合公车扶手实例,进一步阐述了该实验的具体过程及其创新性与实用性.为提升人机工程学实验教学与创新人才培养质量提供了条件.

  15. Moving a hand-held object: Reconstruction of referent coordinate and apparent stiffness trajectories. (United States)

    Ambike, S; Zhou, T; Zatsiorsky, V M; Latash, M L


    This study used the framework of the referent configuration hypothesis and slow changes in the external conditions during vertical oscillation of a hand-held object to infer the characteristics of hypothetical control variables. The study had two main objectives: (1) to show that hypothetical control variables, namely, referent coordinates and apparent stiffness of vertical hand position and grip force can be measured in an experiment; and (2) to establish relation(s) between these control variables that yield the classic grip-force-load-force coupling. Healthy subjects gripped a handle and performed vertical oscillations between visual targets at one of five metronome-prescribed frequencies. A HapticMaster robot was used to induce slow changes in the vertical force applied to the handle, while the size of the handle was changed slowly leading to changes in the grip aperture. The subjects were instructed not to react to possible changes in the external forces. A linear, second-order model was used to reconstruct the referent coordinate and apparent stiffness values for each phase of the vertical oscillation cycle using across-cycle regressions. The reconstructed time profiles of the referent coordinates and apparent stiffness showed consistent trends across subjects and movement frequencies. To validate the method, these values were used to predict the vertical force and the grip force applied to the handle for movement cycles that were not utilized in the reconstruction process. Analysis of the coupling between the four variables, two referent coordinates and two apparent stiffness values, revealed a single strong constraint reflecting the coupling between the grip force and vertical force. We view these data as providing experimental support for the idea of controlling natural, multi-muscle actions with shifts in a low-dimensional set of referent coordinates.

  16. Utility of hand-held echocardiography in outpatient pediatric cardiology management. (United States)

    Riley, Alan; Sable, Craig; Prasad, Aparna; Spurney, Christopher; Harahsheh, Ashraf; Clauss, Sarah; Colyer, Jessica; Gierdalski, Marcin; Johnson, Ashley; Pearson, Gail D; Rosenthal, Joanna


    Adult patient series have shown hand-held echocardiography (echo) units (HHE) to be accurate for rapid diagnosis and triage. This is the first study to evaluate the ability of HHE to inform decision making in outpatient pediatric cardiology. New pediatric cardiology patients in outpatient clinics staffed by six pediatric cardiologists (experience 1-17 years) were prospectively enrolled if an echocardiogram (echo) was ordered during their initial visit. After history and physical examination and before a standard echo, the cardiologists performed a bedside HHE examination (GE Vscan 1.7-3.8 MHz), documented findings, and made a clinical decision. Diagnoses and decisions based on HHE were compared with final management after the standard echo. The study enrolled 101 subjects (ages 9 days to 19 years). The cardiologists considered HHE imaging adequate for decision making for 80 of the 101 subjects. For 77 of the 80 subjects with acceptable HHE imaging (68/68 normal and 9/12 abnormal standard echoes), the HHE-based primary diagnoses and decisions agreed with the final management. The sensitivity of HHE was 75 % (95 % confidence interval [CI] 43-94 %) and the positive predictive value 100 % (95 % CI 66-100 %) for pediatric heart disease. The agreement between standard echocardiography and HHE imaging was substantial (κ = 0.82). Excluding one of the least experienced cardiologists, HHE provided the basis for correct cardiac diagnoses and management for all the subjects with acceptable HHE imaging (58/58 normal and 9/9 abnormal echoes). In outpatient pediatric cardiology, HHE has potential as a tool to complement physical examination. Further investigation is needed to evaluate how value improves with clinical experience.

  17. Group differences in physician responses to handheld presentation of clinical evidence: a verbal protocol analysis

    Directory of Open Access Journals (Sweden)

    Pavlovic Nada J


    Full Text Available Abstract Background To identify individual differences in physicians' needs for the presentation of evidence resources and preferences for mobile devices. Methods Within-groups analysis of responses to semi-structured interviews. Interviews consisted of using prototypes in response to task-based scenarios. The prototypes were implemented on two different form factors: a tablet style PC and a pocketPC. Participants were from three user groups: general internists, family physicians and medicine residents, and from two different settings: urban and semi-urban. Verbal protocol analysis, which consists of coding utterances, was conducted on the transcripts of the testing sessions. Statistical relationships were investigated between staff physicians' and residents' background variables, self-reported experiences with the interfaces, and verbal code frequencies. Results 47 physicians were recruited from general internal medicine, family practice clinics and a residency training program. The mean age of participants was 42.6 years. Physician specialty had a greater effect on device and information-presentation preferences than gender, age, setting or previous technical experience. Family physicians preferred the screen size of the tablet computer and were less concerned about its portability. Residents liked the screen size of the tablet, but preferred the portability of the pocketPC. Internists liked the portability of the pocketPC, but saw less advantage to the large screen of the tablet computer (F[2,44] = 4.94, p = .012. Conclusion Different types of physicians have different needs and preferences for evidence-based resources and handheld devices. This study shows how user testing can be incorporated into the process of design to inform group-based customization.

  18. 嵌入式掌上娱乐系统%Embedded Handheld Entertainment System

    Institute of Scientific and Technical Information of China (English)

    霍崇浩; 郝卫东; 蒋杰


    在UP-TECH S3C2410 DVK1.1开发平台下,设计并实现了一个触摸式的嵌入式掌上娱乐系统.本系统主要包括多媒体播放器和游戏的基本功能.本系统可以播放现有的大多数的音频视频文件;设计了嵌入式游戏,增加了系统的娱乐性.使用触摸屏方便作为人机交互的平台.采用跨平台性能良好的Qt4设计了应用程序和人机界面,界面友好,汉化显示,美观,操作简便,运行流畅.整个系统模块化设计,充分考虑了软件系统自身所占的存储空间以及可扩展性,具有广阔的市场前景.%The system realizes an embedded handheld entertainment system based on Linux in UP-TECH S3C2410 DVK1.1 development platform. The system includes multi-media player and game. This system can play most of the existing audio and video files. This paper designs an embedded game, and brings much entertaining to the system. It uses touch screen as man-machine interactive platform, bringing much convenience. Qt4 is used to design applications and friendly interactive interface which supports for Chinese display, beautiful, easy to handle, run smoothly. Considering the software system's storage space and expansibility, it has a broad market prospect to choose modular design in the whole system.

  19. Accuracy of Handheld Point-of-Care Fingertip Lactate Measurement in the Emergency Department

    Directory of Open Access Journals (Sweden)

    Gaieski, David G


    Full Text Available Introduction: Early recognition of elevated lactate levels in sepsis may hasten the detection of those patients eligible for aggressive resuscitation. Point-of-care (POC testing is now increasingly available for use in the emergency department (ED. We examined the accuracy and time-saving effect of a handheld POC device for the measurement of fingertip and whole blood lactate as compared with reference laboratory testing in critically ill ED patients.Methods: A convenience sample of adult ED patients receiving serum lactate testing was prospectively enrolled at an urban, tertiary care US hospital. Consenting patients underwent fingertip POC lactate measurement with a portable device and simultaneous whole blood sampling for analysis by both the POC device and standard laboratory analyzer (‘‘reference method’’. Lactate measurements were compared by intraclass correlation (ICC and Bland and Altman plots. Differences in time to test result were compared by paired t test.Results: Twenty-four patients, 19 (79% with sepsis and 21 (88% with lactate levels below 4 mmol/L, were included from April 2005 to May 2005. Fingertip POC and whole blood POC lactate measurements each correlated tightly with the reference method (ICC ¼ 0.90 and ICC ¼ 0.92, respectively. Mean time between obtaining fingertip lactate samples and whole blood reference lactate samples was 8 6 13 minutes. Mean time between obtaining POC and reference laboratory lactate results was 65 minutes (95% confidence interval, 30–103.Conclusion: Fingertip POC lactate measurement is an accurate method to determine lactate levels in infected ED patients with normal or modestly elevated lactate values and significantly decreases time to test results. These findings should be verified in a larger, more critically ill, ED population. [West J Emerg Med. 2013;14(1:58-62.

  20. 基于FPGA的手持式示波器设计%Design of handheld oscilloscope based on FPGA

    Institute of Scientific and Technical Information of China (English)

    王庆春; 何晓燕


      在此设计的低成本手持式示波器是以ADC128S022模/数转换芯片为数据采集前端;使用FPGA片内双口内建RAM进行数据存储、有限状态机实现示波器的触发控制和显示驱动;最后再用LCD12864液晶模块完成终端的低成本图形显示。在DE0⁃Nano FPGA(Altera Cyclone IV)开发板上的测试结果表明,所设计的手持式示波器可以实现模拟信号任意电平上升沿或下降沿的触发测量;垂直灵敏度和扫描速度调节、波形参数的直接读出等功能。%The analog⁃to⁃digital conversion chip ADC128S022 is taken as the data acquisition front⁃end in the design pro⁃cess of low⁃cost handheld oscilloscope. The FPGA on⁃chip dual⁃port RAM is used for data storage. A finite state machine is em⁃ployed to achieve the trigger control and display driver of the handheld oscilloscope. The LCD module LCD12864 is used to com⁃plete the low⁃cost terminal graphics display. Moreover,the results testing on the DE0⁃Nano FPGA(Altera Cyclone IV)develop⁃ment board show that the low⁃cost handheld oscilloscope can realize the functions of trigger measurement,vertical sensitivity ad⁃justment,scan speed adjustment and direct readout of waveform parameters at analog signal rising edge or falling edge at any electric level.

  1. Promising Properties and System Demonstration of an Environmentally Benign Yellow Smoke Formulation for Hand-Held Signals (United States)


    prototype assembly has also been demonstrated by flight tests in actual system hardware containing the rocket motor and associated propellant . KEYWORDS...configurations (baseline, I, and II) was loaded into the full hand-held signal hardware containing the rocket motor and propellant and then deployed on an...consisting of 33.0 wt % potassium nitrate, 24.5 wt % silicon, 20.8 wt % black iron oxide, 12.3 wt % aluminum, 3.8 wt % charcoal, and 5.6 wt % nitrocellulose


    Institute of Scientific and Technical Information of China (English)

    Ruan Fangming; Fujiwara Osamu; Gao Yougang


    Characteristic measurement of contact discharge currents are made through a hand-held metal rod from charged human body. Correlation coefficients are obtained, through Statistic Package for Social Science (SPSS), for various charge voltages, which is based on the effect test of electrode contact approach speeds on discharge current parameters of current peaks, maximum rising slope and spark lengths. Discharge parameters at charge voltage 300V are independent on approach speed. For charge voltages equal to and higher than 500V, the contact approach speed has strong positive correlation with discharge parameters of the peak current and the maximum rising slope, whereas has strong negative correlation with the spark length.

  3. A cloud-based multimodality case file for mobile devices. (United States)

    Balkman, Jason D; Loehfelm, Thomas W


    Recent improvements in Web and mobile technology, along with the widespread use of handheld devices in radiology education, provide unique opportunities for creating scalable, universally accessible, portable image-rich radiology case files. A cloud database and a Web-based application for radiologic images were developed to create a mobile case file with reasonable usability, download performance, and image quality for teaching purposes. A total of 75 radiology cases related to breast, thoracic, gastrointestinal, musculoskeletal, and neuroimaging subspecialties were included in the database. Breast imaging cases are the focus of this article, as they best demonstrate handheld display capabilities across a wide variety of modalities. This case subset also illustrates methods for adapting radiologic content to cloud platforms and mobile devices. Readers will gain practical knowledge about storage and retrieval of cloud-based imaging data, an awareness of techniques used to adapt scrollable and high-resolution imaging content for the Web, and an appreciation for optimizing images for handheld devices. The evaluation of this software demonstrates the feasibility of adapting images from most imaging modalities to mobile devices, even in cases of full-field digital mammograms, where high resolution is required to represent subtle pathologic features. The cloud platform allows cases to be added and modified in real time by using only a standard Web browser with no application-specific software. Challenges remain in developing efficient ways to generate, modify, and upload radiologic and supplementary teaching content to this cloud-based platform. Online supplemental material is available for this article.

  4. Evaluation of cone function by a handheld non-mydriatic flicker electroretinogram device

    Directory of Open Access Journals (Sweden)

    Nakamura N


    Full Text Available Natsuko Nakamura,1 Kaoru Fujinami,1 Yoshinobu Mizuno,2 Toru Noda,2 Kazushige Tsunoda11Laboratory of Visual Physiology, Division of Vision Research, National Institute of Sensory Organs, 2Department of Ophthalmology, National Hospital Organization, National Tokyo Medical Center, Tokyo, JapanPurpose: Full-field electroretinograms (ERGs are used to evaluate retinal function in patients with various types of hereditary and acquired retinal diseases. However, ERG recordings require relatively invasive procedures, including pupillary dilation and the use of contact lens electrodes. Thus, it would be helpful to have a simpler and noninvasive screening method. The purpose of this study was to determine whether a new, handheld, portable ERG device, RETeval™, can be used to screen patients for cone dysfunction.Patients and methods: Thirty-five eyes of 35 patients who had reduced cone responses ascertained by a conventional ERG system using contact lens electrodes were studied. The causative diseases included achromatopsia, cone dystrophy, cone-rod dystrophy, retinitis pigmentosa, choroidal dystrophy, autoimmune retinopathy, and Stargardt disease. The flicker ERGs were recorded with the RETeval™ under undilated conditions with skin electrodes (stimulus strength, 3.0 cd·s/m2; frequency, 28.3 Hz, and the responses were compared to that of 50 healthy eyes. The amplitudes and implicit times of the fundamental component of the flicker ERGs were analyzed in three age groups: Group A, ≤20 years; Group B, 21–40 years; and Group C, ≥41 years.Results: In all of the age groups, the amplitudes of the ERGs were significantly smaller and the implicit times significantly longer in patients with cone dysfunction than in the control eyes. All but one of the patients had flicker amplitudes lower than the mean −2.0 standard deviation of control eyes.Conclusion: The RETeval™ has a potential of being used to screen for cone dysfunction. The entire examination

  5. SWIR, VIS and LWIR observer performance against handheld objects: a comparison (United States)

    Adomeit, Uwe


    The short wave infrared spectral range caused interest to be used in day and night time military and security applications in the last years. This necessitates performance assessment of SWIR imaging equipment in comparison to the one operating in the visual (VIS) and thermal infrared (LWIR) spectral range. In the military context (nominal) range is the main performance criteria. Discriminating friend from foe is one of the main tasks in today's asymmetric scenarios and so personnel, human activities and handheld objects are used as targets to estimate ranges. The later was also used for an experiment at Fraunhofer IOSB to get a first impression how the SWIR performs compared to VIS and LWIR. A human consecutively carrying one of nine different civil or military objects was recorded from five different ranges in the three spectral ranges. For the visual spectral range a 3-chip color-camera was used, the SWIR range was covered by an InGaAs-camera and the LWIR by an uncooled bolometer. It was ascertained that the nominal spatial resolution of the three cameras was in the same magnitude in order to enable an unbiased assessment. Daytime conditions were selected for data acquisition to separate the observer performance from illumination conditions and to some extend also camera performance. From the recorded data, a perception experiment was prepared. It was conducted as a nine-alternative forced choice, unlimited observation time test with 15 observers participating. Before the experiment, the observers were trained on close range target data. Outcome of the experiment was the average probability of identification versus range between camera and target. The comparison of the range performance achieved in the three spectral bands gave a mixed result. On one hand a ranking VIS / SWIR / LWIR in decreasing order can be seen in the data, but on the other hand only the difference between VIS and the other bands is statistically significant. Additionally it was not possible

  6. Hip- and knee-strength assessments using a hand-held dynamometer with external belt-fixation are inter-tester reliable

    DEFF Research Database (Denmark)

    Thorborg, Kristian; Bandholm, Thomas; Hölmich, Per


    PURPOSE: In football, ice-hockey, and track and field, injuries have been predicted, and hip- and knee-strength deficits quantified using hand-held dynamometry (HHD). However, systematic bias exists when testers of different sex and strength perform the measurements. Belt-fixation of the dynamome......PURPOSE: In football, ice-hockey, and track and field, injuries have been predicted, and hip- and knee-strength deficits quantified using hand-held dynamometry (HHD). However, systematic bias exists when testers of different sex and strength perform the measurements. Belt...

  7. A new hand-held microfluidic cytometer for evaluating irradiation damage by analysis of the damaged cells distribution (United States)

    Wang, Junsheng; Fan, Zhiqiang; Zhao, Yile; Song, Younan; Chu, Hui; Song, Wendong; Song, Yongxin; Pan, Xinxiang; Sun, Yeqing; Li, Dongqing


    Space radiation brings uneven damages to cells. The detection of the distribution of cell damage plays a very important role in radiation medicine and the related research. In this paper, a new hand-held microfluidic flow cytometer was developed to evaluate the degree of radiation damage of cells. The device we propose overcomes the shortcomings (e.g., large volume and high cost) of commercial flow cytometers and can evaluate the radiation damage of cells accurately and quickly with potential for onsite applications. The distribution of radiation-damaged cells is analyzed by a simultaneous detection of immunofluorescence intensity of γ-H2AX and resistance pulse sensor (RPS) signal. The γ-H2AX fluorescence intensity provides information of the degree of radiation damage in cells. The ratio of the number of cells with γ-H2AX fluorescence signals to the total numbers of cells detected by RPS indicates the percentage of the cells that are damaged by radiation. The comparison experiment between the developed hand-held microfluidic flow cytometer and a commercial confocal microscope indicates a consistent and comparable detection performance.

  8. Development and performance of a hand-held CZT detector for in-situ measurements at the emergency response

    Energy Technology Data Exchange (ETDEWEB)

    Ji, Young Yong; Chung, Kun Ho; Kim, Chang Jong; Lee, Wan No; Choi, Geun Sik; Kang, Mun Ja [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Yoon, Jin [SI Detection Co. Ltd, Daejeon (Korea, Republic of)


    A hand-held detector for an emergency response was developed for nuclide identification and to estimate the information of the ambient dose rate in the scene of an accident as well as the radioactivity of the contaminants. To achieve this, the most suitable sensor was first selected as a cadmium zinc telluride (CZT) semiconductor and the signal processing unit from a sensor and the signal discrimination and storage unit were successfully manufactured on a printed circuit board. The performance of the developed signal processing unit was then evaluated to have an energy resolution of about 14 keV at 662 keV. The system control unit was also designed to operate the CZT detector, monitor the detector, battery, and interface status, and check and transmit the measured results of the ambient dose rate and radioactivity. In addition, a collimator, which can control the inner radius, and the airborne dust sampler, which consists of an air filter and charcoal filter, were developed and mounted to the developed CZT detector for the quick and efficient response of a nuclear accident. The hand-held CZT detector was developed to make the in-situ gamma-ray spectrometry and its performance was checked to have a good energy resolution. In addition, the collimator and the airborne dust sampler were developed and mounted to the developed CZT detector for a quick and efficient response to a nuclear accident.

  9. Handheld Devices and Video Modeling to Enhance the Learning of Self-Help Skills in Adolescents With Autism Spectrum Disorder. (United States)

    Campbell, Joseph E; Morgan, Michele; Barnett, Veronica; Spreat, Scott


    The viewing of videos is a much-studied intervention to teach self-help, social, and vocational skills. Many of the studies to date looked at video modeling using televisions, computers, and other large screens. This study looked at the use of video modeling on portable handheld devices to teach hand washing to three adolescent students with an autism spectrum disorder. Three students participated in this 4-week study conducted by occupational therapists. Baseline data were obtained for the first student for 1 week, the second for 2 weeks, and the third for 3 weeks; videos were introduced when the participants each finished the baseline phase. Given the cognitive and motor needs of the participants, the occupational therapist set the player so that the participants only had to press the play button to start the video playing. The participants were able to hold the players and view at distances that were most appropriate for their individual needs and preferences. The results suggest that video modeling on a handheld device improves the acquisition of self-help skills.

  10. Calibration of handheld X-ray fluorescence (XRF) equipment for optimum determination of elemental concentrations in sediment samples. (United States)

    Mejía-Piña, K Gabriela; Huerta-Diaz, Miguel Angel; González-Yajimovich, O


    Handheld X-ray fluorescence spectrometers (XRFs) represent a more practical, efficient and economic tool to determine the elemental composition of solid inorganic and organic samples than conventional analytical techniques. The objective of this work was to demonstrate that handheld XRFs could be a precise, accurate and reliable tool to analyze up to 27 different elements. This objective was accomplished through the optimization of an empirical calibration curve that, in addition to include certified reference materials (CRM), it also introduced new approaches, such as the use of solid CRM mixtures and combinations of organic and inorganic matrices. These approaches significantly increased the number of calibration points and eliminated hiatuses in the calibration curve. Several factors were evaluated before construction of the calibration curve: incidence time of the X-ray beam, type of film through which the X-ray beams reach the samples, container type, minimum sample volume and sample moisture content. Results show that single elements can be analyzed with variable exposure times or, alternatively, multielemental analyses can be carried out with a constant exposure time (180s). Costs can be reduced by using Ziploc(®) bags as sample containers, but the number of measurable elements drops from 27 to 21, while the possibility of contamination increases.

  11. The impact of mobile handheld technology on hospital physicians' work practices and patient care: a systematic review. (United States)

    Prgomet, Mirela; Georgiou, Andrew; Westbrook, Johanna I


    The substantial growth in mobile handheld technologies has heralded the opportunity to provide physicians with access to information, resources, and people at the right time and place. But is this technology delivering the benefits to workflow and patient care promised by increased mobility? The authors conducted a systematic review to examine evidence regarding the impact of mobile handheld technology on hospital physicians' work practices and patient care, focusing on quantification of the espoused virtues of mobile technologies. The authors identified thirteen studies that demonstrated the ability of personal digital assistants (PDAs) to positively impact on areas of rapid response, error prevention, and data management and accessibility. The use of PDAs demonstrates the greatest benefits in contexts where time is a critical factor and a rapid response crucial. However, the extent to which these devices improved outcomes and workflow efficiencies because of their mobility was largely absent from the literature. The paucity of evidence calls for much needed future research that asks explicit questions about the impact the mobility of devices has on work practices and outcomes.

  12. Comparison of the DiSCmini aerosol monitor to a handheld condensation particle counter and a scanning mobility particle sizer for submicrometer sodium chloride and metal aerosols. (United States)

    Mills, Jessica B; Park, Jae Hong; Peters, Thomas M


    We evaluated the robust, lightweight DiSCmini (DM) aerosol monitor for its ability to measure the concentration and mean diameter of submicrometer aerosols. Tests were conducted with monodispersed and polydispersed aerosols composed of two particle types (sodium chloride [NaCl] and spark-generated metal particles, which simulate particles found in welding fume) at three different steady-state concentration ranges (Low, 10(4) particles/cm(3)). Particle number concentration, lung deposited surface area (LDSA) concentration, and mean size measured with the DM were compared with those measured with reference instruments, a scanning mobility particle sizer (SMPS), and a handheld condensation particle counter (CPC). Particle number concentrations measured with the DM were within 16% of those measured by the CPC for polydispersed aerosols. Poorer agreement was observed for monodispersed aerosols (±35% for most tests and +101% for 300-nm NaCl). LDSA concentrations measured by the DM were 96% to 155% of those estimated with the SMPS. The geometric mean diameters measured with the DM were within 30% of those measured with the SMPS for monodispersed aerosols and within 25% for polydispersed aerosols (except for the case when the aerosol contained a substantial number of particles larger than 300 nm). The accuracy of the DM is reasonable for particles smaller than 300 nm, but caution should be exercised when particles larger than 300 nm are present. [Supplementary materials are available for this article. Go to the publisher's online edition of the Journal of Occupational and Environmental Hygiene for the following free supplemental resources: manufacturer-reported capabilities of instruments used, and information from the SMPS measurements for polydispersed test particles.].

  13. Preliminary study on the treatment of masturbation ejaculation dififculty with handheld stimulating device assisted behavior therapy%自慰器辅助行为治疗对自慰射精困难的疗效初探

    Institute of Scientific and Technical Information of China (English)

    范宇平; 马逸; 刘国霖; 胡烨; 黄文强; 黄媚媛; 滕晓明


    目的:回顾性分析男科门诊体外受精(in vitro fertilization, IVF)术前主诉通过自慰取精困难的患者,评价自慰器辅助行为治疗的疗效。方法选择2013年8月至2014年5月在上海市第一妇婴保健院生殖中心行IVF治疗的、有射精困难(排除自慰和性生活均不能射精等情况)的患者53例。由患者及家属自主选择治疗方案,倾向优先器械辅助行为治疗的患者31例,占58.49%。根据选择的治疗方法将患者分为两组,治疗组31例,对照组22例。治疗组患者在治疗期间规律射精频率、保持生活习惯,前2周自行采用自慰器,通过视听刺激于家中尝试取精,后2周每周1~2次于手术取精室进行模拟治疗,成功取精后进行1个月维持治疗。在术前选择冷冻保存精子的患者共39例(治疗组20例,对照组19例)。结果治疗组31例患者,在治疗阶段自行通过自慰器成功取精25例(80.65%)。在手术当日,治疗组成功取精19例(61.29%),使用术前冷冻精子10例(32.26%),手术当日睾丸穿刺取精2例(6.45%)。对照组成功取精7例(31.82%),使用术前冷冻精子12例(54.55%),手术当日睾丸穿刺取精3例(13.64%)。两组患者手术当日取精成功率比较差异有显著统计学意义(P<0.05)。而在术前冷冻精子的39例患者和未冷冻精子的14例患者手术日取精成功率比较差异无统计学意义(P>0.05)。结论自慰器辅助行为治疗对自慰射精困难的患者有一定疗效。但如何取得更好的疗效及明确机制尚待进一步大样本、多中心的深入研究。%Objective To evaluate the effect of handheld stimulating device assisted behaviour therapy on masturbation ejaculation difficulty of the patients from IVF (in vitro fertilization, IVF) outpatient.Methods Total of 67 cases who complained masturbation ejaculation difficulty during the IVF cycle from August 2013 to

  14. WWC Review of the Report "Conceptualizing Astronomical Scale: Virtual Simulations on Handheld Tablet Computers Reverse Misconceptions." What Works Clearinghouse Single Study Review (United States)

    What Works Clearinghouse, 2014


    The 2014 study, "Conceptualizing Astronomical Scale: Virtual Simulations on Handheld Tablet Computers Reverse Misconceptions," examined the effects of using the true-to-scale (TTS) display mode versus the orrery display mode in the iPad's Solar Walk software application on students' knowledge of the Earth's place in the solar system. The…

  15. Yield of screening for atrial fibrillation in primary care with a hand-held, single-lead electrocardiogram device during influenza vaccination

    NARCIS (Netherlands)

    Kaasenbrood, Femke; Hollander, Monika; Rutten, Frans H.; Gerhards, Leo J.; Hoes, Arno W.; Tieleman, Robert G.


    Aims To assess the yield of screening for atrial fibrillation (AF) with a hand-held single-lead electrocardiogram (ECG) device during influenza vaccination in primary care in the Netherlands. Methods and results We used the MyDiagnostick to screen for AF in persons who participated in influenza vacc

  16. Beyond Textbook Illustrations: Hand-Held Models of Ordered DNA and Protein Structures as 3D Supplements to Enhance Student Learning of Helical Biopolymers (United States)

    Jittivadhna, Karnyupha; Ruenwongsa, Pintip; Panijpan, Bhinyo


    Textbook illustrations of 3D biopolymers on printed paper, regardless of how detailed and colorful, suffer from its two-dimensionality. For beginners, computer screen display of skeletal models of biopolymers and their animation usually does not provide the at-a-glance 3D perception and details, which can be done by good hand-held models. Here, we…

  17. Evaluation of surface-enhanced Raman scattering detection using a handheld and a bench-top Raman spectrometer: a comparative study. (United States)

    Zheng, Jinkai; Pang, Shintaro; Labuza, Theodore P; He, Lili


    Surface enhanced Raman scattering (SERS) detection using a handheld Raman spectrometer and a bench-top Raman spectrometer was systemically evaluated and compared in this study. Silver dendrites were used as the SERS substrate, and two pesticides, maneb and pyrrolidine dithiocarbamate-ammonium salt (PDCA) were used as the analytes. Capacity and performance were evaluated based on spectral resolution, signal variation, quantitative capacity, sensitivity, flexibility and intelligence for SERS detection. The results showed that the handheld Raman spectrometer had better data consistency, more accurate quantification capacity, as well as the capacity of on-site and intelligence for qualitative and semi-quantitative analysis. On the other hand, the bench-top Raman spectrometer showed about 10 times higher sensitivity, as well as flexibility for optimization of the SERS measurements under different parameters such as laser power output, collective time, and objective magnification. The study on the optimization of SERS measurements on a bench-top spectrometer provides a useful guide for designing a handheld Raman spectrometer, specifically for SERS detection. This evaluation can advance the application of a handheld Raman spectrometer for the on-site measurement of trace amounts of pesticides or other chemicals.

  18. Inter-tester Reliability of the Hand-held dynamometer and the Leg Extensor Power Rig applied on Patients after Total Hip Arthroplasty

    DEFF Research Database (Denmark)

    Mikkelsen, Lone Ramer; Mechlenburg, Inger; Petersen, Annemette Krintel;

    INTRODUCTION: Rehabilitation has an increasing focus on intensive resistance training early after joint replacement (1,2). This increases the requests for measuring changes in the muscle strength and muscle power over time. Hand-held dynamometer (HHD) is a device used to measure isometric muscle...

  19. Inter-tester Reliability of the Hand-held dynamometer and the Leg Extensor Power Rig applied on Patients after Total Hip Arthroplasty

    DEFF Research Database (Denmark)

    Mikkelsen, Lone Ramer; Petersen, Annemette Krintel; Mikkelsen, Søren Søndergaard;

    Background: Rehabilitation has an increasing focus on intensive resistance training early after joint replacement. This increases the requests for measuring changes in the muscle strength and muscle power over time. Hand-held dynamometer (HHD) is a device used to measure isometric muscle strength...

  20. Inter-Tester Reliability and Precision of Manual Muscle Testing and Hand-Held Dynamometry in Lower Limb Muscles of Children with Spina Bifida (United States)

    Mahony, Kate; Hunt, Adrienne; Daley, Deborah; Sims, Susan; Adams, Roger


    Reliability and measurement precision of manual muscle testing (MMT) and hand-held dynamometry (HHD) were compared for children with spina bifida. Strength measures were obtained of the hip flexors, hip abductors, and knee extensors of 20 children (10 males, 10 females; mean age 9 years 10 months; range: 5 to 15 years) by two experienced physical…

  1. First demonstration of real-time gamma imaging by using a handheld Compton camera for particle therapy

    Energy Technology Data Exchange (ETDEWEB)

    Taya, T., E-mail: [Research Institute for Science and Engineering, Waseda University, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555 (Japan); Kataoka, J.; Kishimoto, A.; Iwamoto, Y.; Koide, A. [Research Institute for Science and Engineering, Waseda University, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555 (Japan); Nishio, T. [Graduate School of Biomedical and Health Science, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima-shi, Hiroshima (Japan); Kabuki, S. [School of Medicine, Tokai University, 143 Shimokasuya, Isehara-shi, Kanagawa (Japan); Inaniwa, T. [National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba-shi, Chiba (Japan)


    The use of real-time gamma imaging for cancer treatment in particle therapy is expected to improve the accuracy of the treatment beam delivery. In this study, we demonstrated the imaging of gamma rays generated by the nuclear interactions during proton irradiation, using a handheld Compton camera (14 cm×15 cm×16 cm, 2.5 kg) based on scintillation detectors. The angular resolution of this Compton camera is ∼8° at full width at half maximum (FWHM) for a {sup 137}Cs source. We measured the energy spectra of the gamma rays using a LaBr{sub 3}(Ce) scintillator and photomultiplier tube, and using the handheld Compton camera, performed image reconstruction when using a 70 MeV proton beam to irradiate a water, Ca(OH){sub 2}, and polymethyl methacrylate (PMMA) phantom. In the energy spectra of all three phantoms, we found an obvious peak at 511 keV, which was derived from annihilation gamma rays, and in the energy spectrum of the PMMA phantom, we found another peak at 718 keV, which contains some of the prompt gamma rays produced from {sup 10}B. Therefore, we evaluated the peak positions of the projection from the reconstructed images of the PMMA phantom. The differences between the peak positions and the Bragg peak position calculated using simulation are 7 mm±2 mm and 3 mm±8 mm, respectively. Although we could quickly acquire online gamma imaging of both of the energy ranges during proton irradiation, we cannot arrive at a clear conclusion that prompt gamma rays sufficiently trace the Bragg peak from these results because of the uncertainty given by the spatial resolution of the Compton camera. We will develop a high-resolution Compton camera in the near future for further study. - Highlights: • Gamma imaging during proton irradiation by a handheld Compton camera is demonstrated. • We were able to acquire the online gamma-ray images quickly. • We are developing a high resolution Compton camera for range verification.

  2. Maintaining radiation exposures as low as reasonably achievable (ALARA) for dental personnel operating portable hand-held x-ray equipment. (United States)

    McGiff, Thomas J; Danforth, Robert A; Herschaft, Edward E


    Clinical experience indicates that newly available portable hand-held x-ray units provide advantages compared to traditional fixed properly installed and operated x-ray units in dental radiography. However, concern that hand-held x-ray units produce higher operator doses than fixed x-ray units has caused regulatory agencies to mandate requirements for use of hand-held units that go beyond those recommended by the manufacturer and can discourage the use of this technology. To assess the need for additional requirements, a hand-held x-ray unit and a pair of manikins were used to measure the dose to a simulated operator under two conditions: exposures made according to the manufacturer's recommendations and exposures made according to manufacturer's recommendation except for the removal of the x-ray unit's protective backscatter shield. Dose to the simulated operator was determined using an array of personal dosimeters and a pair of pressurized ion chambers. The results indicate that the dose to an operator of this equipment will be less than 0.6 mSv y⁻¹ if the device is used according to the manufacturer's recommendations. This suggests that doses to properly trained operators of well-designed, hand-held dental x-ray units will be below 1.0 mSv y⁻¹ (2% of the annual occupational dose limit) even if additional no additional operational requirements are established by regulatory agencies. This level of annual dose is similar to those reported as typical dental personnel using fixed x-ray units and appears to satisfy the ALARA principal for this class of occupational exposures.

  3. Analysis of pre-Islamic ceramics from the Kur River Basin (Fars, Iran) using handheld X-ray fluorescence spectrometry (United States)

    Pincé, Possum; Vekemans, Bart; Vandenabeele, Peter; Haerinck, Ernie; Overlaet, Bruno


    A large number of painted pre-Islamic ceramics from the Kur River Basin (Fars province, Iran) was collected on surveys and excavations conducted by the late Prof. L. Vanden Berghe (Ghent University, Belgium) during the 1950s. Handheld X-ray fluorescence spectrometry was undertaken on a selection of these ceramics to evaluate the applicability of the technique to study the fabric of these ceramics and the pigments used for decoration. The aim is to obtain elemental data, from which information about raw materials, manufacturing techniques and exchange systems can be extracted. A total of 26 sherds was analyzed dating from the Neolithic to the Late Bronze Age and belonging to different sites and styles. Five compositional groups could be identified in the dataset. These elemental groups differ from the groups obtained by the macroscopic study and are related to the production process and/or the provenance of the primary materials.


    Energy Technology Data Exchange (ETDEWEB)

    Couture, A.


    Nuclear facilities sometimes use hand-held plastic scintillator detectors to detect attempts to divert special nuclear material in situations where portal monitors are impractical. MCNP calculations have been performed to determine the neutron and gamma radiation field arising from a Category I quantity of weapons-grade plutonium in various shielding configurations. The shields considered were composed of combinations of lead and high-density polyethylene such that the mass of the plutonium plus shield was 22.7 kilograms. Monte-Carlo techniques were also used to determine the detector response to each of the shielding configurations. The detector response calculations were verified using field measurements of high-, medium-, and low- energy gamma-ray sources as well as a Cf-252 neutron source.


    Energy Technology Data Exchange (ETDEWEB)



    Frisch-ring CdZnTe detectors have demonstrated good energy resolution, el% FWHM at 662 keV, and good efficiency for detecting gamma rays. This technique facilitates the application of CdZnTe materials for high efficiency gamma-ray detection. A hand-held gamma-ray spectrometer based on Frisch-ring detectors is being designed at Brookhaven National Laboratory. It employs an 8x8 CdZnTe detector array to achieve a high volume of 19.2 cm3, so that detection efficiency is significantly improved. By using the front-end ASICs developed at BNL, this spectrometer has a small profile and high energy resolution. The spectrometer includes signal processing circuit, digitization and storage circuit, high-voltage module, and USB interface. In this paper, we introduce the details of the system structure and report our test results with it.

  6. Pre-test habituation improves the reliability of a handheld test of mechanical nociceptive threshold in dairy cows

    DEFF Research Database (Denmark)

    Raundal, P. M.; Andersen, P. H.; Toft, Nils;


    Mechanical nociceptive threshold (MNT) testing has been used to investigate aspects of painful states in bovine claws. We investigated a handheld tool, where the applied stimulation force was monitored continuously relative to a pre-encoded based target force. The effect on MNT of two pre......-testing habituation procedures was performed in two different experiments comprising a total of 88 sound Holsteins dairy cows kept either inside or outside their home environment. MNT testing was performed using five consecutive mechanical nociceptive stimulations per cow per test at a fixed pre-encoded target rate...... of 2.1 N/s. The habituation procedure performed in dairy cows kept in their home environment led to lowered intra-individual coefficient of variation of MNT (P force during stimulations (P

  7. 手持式快速心电检测仪设计%The Design of Handheld Fast ECG Detector

    Institute of Scientific and Technical Information of China (English)

    石波; 张根选; 曹阳


    A new handheld fast ECG detector based on low gain amplifier, the high resolution analog to digital converter, the real-time digital filter, fast P-QRS-T wave detection and ion algorithm was designed. The results showed that the ECG detector can meet the requirements of fast detecting heart rate and ECG P-QRS-T waveforms.%  采用低倍数放大、高分辨率模数转换、实时数字滤波以及快速P-QRS-T波形识别和提取算法等技术,设计了一种手持式快速心电检测仪。结果表明,该心电检测仪能够满足心率和心电图P-QRS-T波形快速检测的要求。

  8. Hand-held multi-DOF robotic forceps for neurosurgery designed for dexterous manipulation in deep and narrow space. (United States)

    Okubo, Takuro; Harada, Kanako; Fujii, Masahiro; Tanaka, Shinichi; Ishimaru, Tetsuya; Iwanaka, Tadashi; Nakatomi, Hirohumi; Sora, Sigeo; Morita, Akio; Sugita, Naohiko; Mitsuishi, Mamoru


    Neurosurgical procedures require precise and dexterous manipulation of a surgical suture in narrow and deep spaces in the brain. This is necessary for surgical tasks such as the anastomosis of microscopic blood vessels and dura mater suturing. A hand-held multi-degree of freedom (DOF) robotic forceps was developed to aid the performance of such difficult tasks. The diameter of the developed robotic forceps is 3.5 mm, and its tip has three DOFs, namely, bending, rotation, and grip. Experimental results showed that the robotic forceps had an average needle insertion force of 1.7 N. Therefore, an increase in the needle insertion force is necessary for practical application of the developed device.

  9. US-ROK Action Sheet 34: Safeguards Application of a Hand-held Mechanically Cooled Germanium Spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Dreyer, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Burks, M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ham, Y. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kwak, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    This report summarizes results of Action Sheet 34 - for the cooperative efforts on the field testing and evaluation of a high-resolution, hand-held, gamma-ray spectrometer, known as SPG (Spectroscopic Planar Germanium), for safeguards application such as short notice inspections, UF6 analysis, enrichment determination, and other potential applications. The Spectroscopic Planar Germanium (SPG) has been demonstrated IAEA Physical Inventory Verification (PIV) in South Korea. This field test was a success and the feedback provided by KINAC, IAEA, and national laboratory staff was used to direct efforts to improve the instrument this year. Key points in this report include measurement results from PIV, analysis of spectra with commercially available Ortec U235 and PC-FRAM, and completion of tripod and tungsten collimator and integration of user feedback.

  10. Cellphone-based hand-held microplate reader for point-of-care ELISA testing (Conference Presentation) (United States)

    Berg, Brandon; Cortazar, Bingen; Tseng, Derek; Ozkan, Haydar; Feng, Steve; Wei, Qingshan; Chan, Raymond Y.; Burbano, Jordi; Farooqui, Qamar; Lewinski, Michael; Di Carlo, Dino; Garner, Omai B.; Ozcan, Aydogan


    Enzyme-linked immunosorbent assay (ELISA) in a microplate format has been a gold standard first-line clinical test for diagnosis of various diseases including infectious diseases. However, this technology requires a relatively large and expensive multi-well scanning spectrophotometer to read and quantify the signal from each well, hindering its implementation in resource-limited-settings. Here, we demonstrate a cost-effective and handheld smartphone-based colorimetric microplate reader for rapid digitization and quantification of immunoserology-related ELISA tests in a conventional 96-well plate format at the point of care (POC). This device consists of a bundle of 96 optical fibers to collect the transmitted light from each well of the microplate and direct all the transmission signals from the wells onto the camera of the mobile-phone. Captured images are then transmitted to a remote server through a custom-designed app, and both quantitative and qualitative diagnostic results are returned back to the user within ~1 minute per 96-well plate by using a machine learning algorithm. We tested this mobile-phone based micro-plate reader in a clinical microbiology lab using FDA-approved mumps IgG, measles IgG, and herpes simplex virus IgG (HSV-1 and HSV-2) ELISA tests on 1138 remnant patient samples (roughly 50% training and 50% testing), and achieved an overall accuracy of ~99% or higher for each ELISA test. This handheld and cost-effective platform could be immediately useful for large-scale vaccination monitoring in low-infrastructure settings, and also for other high-throughput disease screening applications at POC.

  11. Handheld and mobile hyperspectral imaging sensors for wide-area standoff detection of explosives and chemical warfare agents (United States)

    Gomer, Nathaniel R.; Gardner, Charles W.; Nelson, Matthew P.


    Hyperspectral imaging (HSI) is a valuable tool for the investigation and analysis of targets in complex background with a high degree of autonomy. HSI is beneficial for the detection of threat materials on environmental surfaces, where the concentration of the target of interest is often very low and is typically found within complex scenery. Two HSI techniques that have proven to be valuable are Raman and shortwave infrared (SWIR) HSI. Unfortunately, current generation HSI systems have numerous size, weight, and power (SWaP) limitations that make their potential integration onto a handheld or field portable platform difficult. The systems that are field-portable do so by sacrificing system performance, typically by providing an inefficient area search rate, requiring close proximity to the target for screening, and/or eliminating the potential to conduct real-time measurements. To address these shortcomings, ChemImage Sensor Systems (CISS) is developing a variety of wide-field hyperspectral imaging systems. Raman HSI sensors are being developed to overcome two obstacles present in standard Raman detection systems: slow area search rate (due to small laser spot sizes) and lack of eye-safety. SWIR HSI sensors have been integrated into mobile, robot based platforms and handheld variants for the detection of explosives and chemical warfare agents (CWAs). In addition, the fusion of these two technologies into a single system has shown the feasibility of using both techniques concurrently to provide higher probability of detection and lower false alarm rates. This paper will provide background on Raman and SWIR HSI, discuss the applications for these techniques, and provide an overview of novel CISS HSI sensors focused on sensor design and detection results.

  12. Hand-held portable desorption atmospheric pressure chemical ionization ion source for in situ analysis of nitroaromatic explosives. (United States)

    Jjunju, Fred P M; Maher, Simon; Li, Anyin; Syed, Sarfaraz U; Smith, Barry; Heeren, Ron M A; Taylor, Stephen; Cooks, R Graham


    A novel, lightweight (0.6 kg), solvent- and gas-cylinder-free, hand-held ion source based on desorption atmospheric pressure chemical ionization has been developed and deployed for the analysis of nitroaromatic explosives on surfaces in open air, offering portability for in-field analysis. A small, inexpensive, rechargeable lithium polymer battery was used to power the custom-designed circuitry within the device, which generates up to ±5 kV dc voltage to ignite a corona discharge plasma in air for up to 12 h of continuous operation, and allowing positive- and negative-ion mass spectrometry. The generated plasma is pneumatically transported to the surface to be interrogated by ambient air at a rate of 1-3.5 L/min, compressed using a small on-board diaphragm pump. The plasma source allows liquid or solid samples to be examined almost instantaneously without any sample preparation in the open environment. The advantages of low carrier gas and low power consumption (<6 W), as well as zero solvent usage, have aided in developing the field-ready, hand-held device for trigger-based, "near-real-time" sampling/ionization. Individual nitroaromatic explosives (such as 2,4,6-trinitrotoluene) can be easily detected in amounts as low as 5.8 pg with a linear dynamic range of at least 10 (10-100 pg), a relative standard deviation of ca. 7%, and an R(2) value of 0.9986. Direct detection of several nitroaromatic compounds in a complex mixture without prior sample preparation is demonstrated, and their identities are confirmed by tandem mass spectrometry fragmentation patterns.

  13. Assessment of Lower Limb Muscle Strength and Power Using Hand-Held and Fixed Dynamometry: A Reliability and Validity Study.

    Directory of Open Access Journals (Sweden)

    Benjamin F Mentiplay

    Full Text Available Hand-held dynamometry (HHD has never previously been used to examine isometric muscle power. Rate of force development (RFD is often used for muscle power assessment, however no consensus currently exists on the most appropriate method of calculation. The aim of this study was to examine the reliability of different algorithms for RFD calculation and to examine the intra-rater, inter-rater, and inter-device reliability of HHD as well as the concurrent validity of HHD for the assessment of isometric lower limb muscle strength and power.30 healthy young adults (age: 23±5 yrs, male: 15 were assessed on two sessions. Isometric muscle strength and power were measured using peak force and RFD respectively using two HHDs (Lafayette Model-01165 and Hoggan microFET2 and a criterion-reference KinCom dynamometer. Statistical analysis of reliability and validity comprised intraclass correlation coefficients (ICC, Pearson correlations, concordance correlations, standard error of measurement, and minimal detectable change.Comparison of RFD methods revealed that a peak 200 ms moving window algorithm provided optimal reliability results. Intra-rater, inter-rater, and inter-device reliability analysis of peak force and RFD revealed mostly good to excellent reliability (coefficients ≥ 0.70 for all muscle groups. Concurrent validity analysis showed moderate to excellent relationships between HHD and fixed dynamometry for the hip and knee (ICCs ≥ 0.70 for both peak force and RFD, with mostly poor to good results shown for the ankle muscles (ICCs = 0.31-0.79.Hand-held dynamometry has good to excellent reliability and validity for most measures of isometric lower limb strength and power in a healthy population, particularly for proximal muscle groups. To aid implementation we have created freely available software to extract these variables from data stored on the Lafayette device. Future research should examine the reliability and validity of these variables in

  14. Identification of new psychoactive substances (NPS) using handheld Raman spectroscopy employing both 785 and 1064nm laser sources. (United States)

    Guirguis, Amira; Girotto, Sarah; Berti, Benedetta; Stair, Jacqueline L


    The chemical identification of new psychoactive substances (NPS) in the field is challenging due not only to the plethora of substances available, but also as a result of the chemical complexity of products and the chemical similarity of NPS analogues. In this study, handheld Raman spectroscopy and the use of two excitation wavelengths, 785 and 1064nm, were evaluated for the identification of 60 NPS products. The products contained a range of NPS from classes including the aminoindanes, arylalkylamines, benzodiazepines, and piperidines & pyrrolidines. Identification was initially assessed using the instruments' in built algorithm (i.e., % HQI) and then further by visual inspection of the Raman spectra. Confirmatory analysis was preformed using gas chromatography mass spectrometry. For the 60 diverse products, an NPS was successfully identified via the algorithm in 11 products (18%) using the 785nm source and 29 products (48%) using the 1064nm source. Evaluation of the Raman spectra showed that increasing the excitation wavelength from 785 to 1064nm improved this 'first pass' identification primarily due to a significant reduction in fluorescence, which increased S/N of the characteristic peaks of the substance identified. True positive correlations between internet products and NPS signatures ranged from 57.0 to 91.3% HQI with typical RSDs<10%. Tablet formulations and branded products were particularly challenging as a result of low NPS concentration and high chemical complexity, respectively. This study demonstrates the advantage of using a 1064nm source with handheld Raman spectroscopy for improved 'first pass' NPS identification when minimal spectral processing is required, such as when working in field. Future investigations will focus on the use of mixture algorithms, effect of NPS concentration, and further improvement of spectral libraries.

  15. First demonstration of real-time gamma imaging by using a handheld Compton camera for particle therapy (United States)

    Taya, T.; Kataoka, J.; Kishimoto, A.; Iwamoto, Y.; Koide, A.; Nishio, T.; Kabuki, S.; Inaniwa, T.


    The use of real-time gamma imaging for cancer treatment in particle therapy is expected to improve the accuracy of the treatment beam delivery. In this study, we demonstrated the imaging of gamma rays generated by the nuclear interactions during proton irradiation, using a handheld Compton camera (14 cm×15 cm×16 cm, 2.5 kg) based on scintillation detectors. The angular resolution of this Compton camera is ∼8° at full width at half maximum (FWHM) for a 137Cs source. We measured the energy spectra of the gamma rays using a LaBr3(Ce) scintillator and photomultiplier tube, and using the handheld Compton camera, performed image reconstruction when using a 70 MeV proton beam to irradiate a water, Ca(OH)2, and polymethyl methacrylate (PMMA) phantom. In the energy spectra of all three phantoms, we found an obvious peak at 511 keV, which was derived from annihilation gamma rays, and in the energy spectrum of the PMMA phantom, we found another peak at 718 keV, which contains some of the prompt gamma rays produced from 10B. Therefore, we evaluated the peak positions of the projection from the reconstructed images of the PMMA phantom. The differences between the peak positions and the Bragg peak position calculated using simulation are 7 mm±2 mm and 3 mm±8 mm, respectively. Although we could quickly acquire online gamma imaging of both of the energy ranges during proton irradiation, we cannot arrive at a clear conclusion that prompt gamma rays sufficiently trace the Bragg peak from these results because of the uncertainty given by the spatial resolution of the Compton camera. We will develop a high-resolution Compton camera in the near future for further study.

  16. A handheld and textile-enabled bioimpedance system for ubiquitous body composition analysis. An initial functional validation. (United States)

    Ferreira Gonzalez, Javier; Pau de la Cruz, Ivan; Lindecrantz, Kaj; Seoane, Fernando


    In recent years, many efforts have been made to promote a healthcare paradigm shift from the traditional reactive hospital-centered healthcare approach towards a proactive, patient-oriented and self-managed approach that could improve service quality and help reduce costs while contributing to sustainability. Managing and caring for patients with chronic diseases accounts over 75% of healthcare costs in developed countries. One of the most resource demanding diseases is chronic kidney disease (CKD), which often leads to a gradual and irreparable loss of renal function, with up to 12% of the population showing signs of different stages of this disease. Peritoneal dialysis and home haemodialysis are life-saving home-based renal replacement treatments that, compared to conventional in-center hemodialysis, provide similar long-term patient survival, less restrictions of life-style, such as a more flexible diet, and better flexibility in terms of treatment options and locations. Bioimpedance has been largely used clinically for decades in nutrition for assessing body fluid distributions. Moreover, bioimpedance methods are used to assess the overhydratation state of CKD patients, allowing clinicians to estimate the amount of fluid that should be removed by ultrafiltration. In this work, the initial validation of a handheld bioimpedance system for the assessment of body fluid status that could be used to assist the patient in home-based CKD treatments is presented. The body fluid monitoring system comprises a custom-made handheld tetrapolar bioimpedance spectrometer and a textile-based electrode garment for total body fluid assessment. The system performance was evaluated against the same measurements acquired using a commercial bioimpedance spectrometer for medical use on several voluntary subjects. The analysis of the measurement results and the comparison of the fluid estimations indicated that both devices are equivalent from a measurement performance perspective

  17. Real-time hand-held ultrasound medical-imaging device based on a new digital quadrature demodulation processor. (United States)

    Levesque, Philippe; Sawan, Mohamad


    A fully hardware-based real-time digital wideband quadrature demodulation processor based on the Hilbert transform is proposed to process ultrasound radio frequency signals. The presented architecture combines 2 finite impulse response (FIR) filters to process in-phase and quadrature signals and includes a piecewise linear approximation architecture that performs the required square root operations. The proposed implementation enables flexibility to support different transducers with its ability to load on-the-fly different FIR filter coefficient sets. The complexity and accuracy of the demodulator processor are analyzed with simulated RF data; a normalized residual sum-of-squares cost function is used for comparison with the Matlab Hilbert function. Three implementations are integrated into a hand-held ultrasound system for experimental accuracy and performance evaluation. Real-time images were acquired from a reference phantom, demonstrating the feasibility of using the presented architecture to perform real-time digital quadrature demodulation of ultrasonic signal echoes. Experimental results show that the implementation, using only 2942 slices and 3 dedicated digital multipliers of a low-cost and low-power field-programmable gate array (FPGA) is accurate relative to a comparable software- based system; axial and lateral resolution of 1 mm and 2 mm, respectively, were obtained with a 12-mm piezoelectric transducer without postprocessing. Because the processing and sampling rates are the same, high-frequency ultrasound signals can be processed as well. For a 15-frame-per-second display, the hand-held ultrasonic imaging-processing core (FPGA, memory) requires only 45 mW (dynamic) when using a 5-MHz single-element piezoelectric transducer.

  18. Validation of a new hand-held electronic data capture method for continuous monitoring of subjective appetite sensations

    Directory of Open Access Journals (Sweden)

    King Neil


    Full Text Available Abstract Background When large scale trials are investigating the effects of interventions on appetite, it is paramount to efficiently monitor large amounts of human data. The original hand-held Electronic Appetite Ratings System (EARS was designed to facilitate the administering and data management of visual analogue scales (VAS of subjective appetite sensations. The purpose of this study was to validate a novel hand-held method (EARS II (HP® iPAQ against the standard Pen and Paper (P&P method and the previously validated EARS. Methods Twelve participants (5 male, 7 female, aged 18-40 were involved in a fully repeated measures design. Participants were randomly assigned in a crossover design, to either high fat (>48% fat or low fat (ad libitum lunch was provided immediately before completing a final set of appetite sensations. Results Repeated measures ANOVAs were conducted for ratings of hunger, fullness and desire to eat. There were no significant differences between P&P compared with either EARS or EARS II (p > 0.05. Correlation coefficients between P&P and EARS II, controlling for age and gender, were performed on Area Under the Curve ratings. R2 for Hunger (0.89, Fullness (0.96 and Desire to Eat (0.95 were statistically significant (p Conclusions EARS II was sensitive to the impact of a meal and recovery of appetite during the postprandial period and is therefore an effective device for monitoring appetite sensations. This study provides evidence and support for further validation of the novel EARS II method for monitoring appetite sensations during large scale studies. The added versatility means that future uses of the system provides the potential to monitor a range of other behavioural and physiological measures often important in clinical and free living trials. This study was registered as a clinical trial by Current Controlled Trials (Registration Number - ISRCTN47291569.

  19. Assessment of nickel and cobalt release from 200 unused hand-held work tools for sale in Denmark — Sources of occupational metal contact dermatitis?

    DEFF Research Database (Denmark)

    Thyssen, Jacob P.; Jensen, Peter; Lidén, Carola


    tools for sale in 2 retailers of home improvement and construction products were analyzed qualitatively for metal release using the colorimetric nickel and cobalt spot tests. ResultsNickel release was identified from 5% of 200 work tools using the dimethylglyoxime (DMG) test. In 8 of 10, positive......IntroductionNickel and cobalt allergy remain frequent in dermatitis patients. It is important to determine possible nickel and cobalt exposures at work as these may offer important information to regulators and physicians who perform patch testing. Clinical relevance of metal exposure is usually...... assessed by the treating physician via the medical history and by presentation of allergic contact dermatitis. ObjectivesTo screen unused non-powered hand-held work tools for nickel and cobalt release by using colorimetric spot tests. Materials & methodsA random selection of 200 non-powered hand-held work...

  20. 基于AT91X40系列的手持式触摸屏%Handheld touch screen based on AT91X40 series

    Institute of Scientific and Technical Information of China (English)

    李建海; 刘迪; 孙艳丽


    基于当前手持式触摸屏稳定性不高,性能不可靠的状况,采用AT91X40系列微控制器作为控制芯片,由于该芯片功能强大,集成度高,处理数据能力强,稳定性高,所以基于AT91X40系列的手持式触摸屏具有体积小巧,功能强大,操作简便等特点。手持式触摸屏的显示和输入设备选用了ADS7843和SED1335两种主流触摸和LCD显示芯片。通过现场的实验验证,基于AT91X40系列的手持式触摸屏稳定性高,工作可靠,具有实际应用价值。%Because the stability of hand-held touch screen is not high and the performance conditions are not reliable at present,AT91X40 series microcontroller is used as control chip in this paper. As the chip features a powerfuL,high integration, data processing capability, high stability, handheld touch screen based on AT91X40 series has the features of small, powerful and operation simple. The display and input device of handheld touch screen selected ADS7843 and SED1335 two mainstream touch chips and LCD display. Experimental verification through on-site, handheld touch screen based on AT91X40 series has high stability, reliable, practical value.

  1. Design of Wireless Handheld Magnetic Card Terminal%无线手持磁条卡信息终端设计

    Institute of Scientific and Technical Information of China (English)

    林耀荣; 李想


    A wireless handheld magnetic card terminal is designed, which is based on the lightweight TCP/IP protocol stack LwIP. The wireless handheld magnetic card terminal is composed of ARM MCU, GPRS MODEM MC39i, magnetic card interface, keyboard and LCD module. The users' ID information on a magnetic card is read with the wireless handheld magnetic card terminal, and sent to the central server through GPRS network. The wireless handheld magnetic card terminal has the characteristics of low cost, small volume and low power consumption. It can be used in a variety of applications, such as bonus points enquiry terminal system and hospital information enquiry system.%基于小型TCP/IP协议栈LwIP开发了一个无线手持磁条卡信息终端.无线手持磁条卡信息终端由ARM单片机,GPRS无线MODEM MC39i,磁条卡接口芯片,键盘和LCD模块等组成.无线手持磁条卡信息终端利用磁条卡接口读取磁卡上的用户ID信息,并通过GPRS无线网络与中心服务器互联,进行后台处理.开发的无线手持磁条卡信息终端具有成本低、体积小、功耗低等特点,可以用于会员消费积分查询、医疗就诊查询等应用系统中.

  2. Demonstration of the B4C/NaIO4/PTFE Delay in the U.S. Army Hand-Held Signal (United States)


    KEYWORDS: Pyrotechnic delay, Boron carbide, Periodate, Hand-held signal, Sustainable chemistry ■ INTRODUCTION Pyrotechnic delays provide controlled...UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Armament Research, Development and Engineering Center, U.S. Army RDECOM-ARDEC...Picatinny Arsenal, New Jersey 07806, United States 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10

  3. Improving the accuracy of hand-held X-ray fluorescence spectrometers as a tool for monitoring brominated flame retardants in waste polymers. (United States)

    Guzzonato, A; Puype, F; Harrad, S J


    An optimised method for Br quantification as a metric of brominated flame retardant (BFR) concentrations present in Waste Electrical and Electronic Equipment (WEEE) polymers is proposed as an alternative to the sophisticated, yet time consuming GC-MS methods currently preferred. A hand-held X-ray fluorescence (XRF) spectrometer was validated with Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS). Customized standard materials of specific BFRs in a styrenic polymer were used to perform an external calibration for hand-held XRF ranging from 0.08 to 12 wt% of Br, and cross-checking with LA-ICP-MS having similar LODs (0.0004 wt% for LA-ICP-MS and 0.0011 wt% for XRF). The "thickness calibration" developed here for hand-held XRF and the resulting correction, was applied to 28 real samples and showed excellent (R(2) = 0.9926) accordance with measurements obtained via LA-ICP-MS. This confirms the validity of hand-held XRF as an accurate technique for the determination of Br in WEEE plastics. This is the first use of solid standards to develop a thickness-corrected quantitative XRF measurement of Br in polymers using LA-ICP-MS for method evaluation. Thermal desorption gas chromatography mass spectrometry (TD-GC-MS) was used to confirm the presence of specific BFRs in WEEE polymer samples. We propose that expressing limit values for BFRs in waste materials in terms of Br rather than BFR concentration (based on a conservative assumption about the BFR present), presents a practical solution to the need for an accurate, yet rapid and inexpensive technique capable of monitoring compliance with limit values in situ.

  4. Hand-held dynamometry in patients with haematological malignancies: Measurement error in the clinical assessment of knee extension strength

    Directory of Open Access Journals (Sweden)

    Uebelhart Daniel


    Full Text Available Abstract Background Hand-held dynamometry is a portable and inexpensive method to quantify muscle strength. To determine if muscle strength has changed, an examiner must know what part of the difference between a patient's pre-treatment and post-treatment measurements is attributable to real change, and what part is due to measurement error. This study aimed to determine the relative and absolute reliability of intra and inter-observer strength measurements with a hand-held dynamometer (HHD. Methods Two observers performed maximum voluntary peak torque measurements (MVPT for isometric knee extension in 24 patients with haematological malignancies. For each patient, the measurements were carried out on the same day. The main outcome measures were the intraclass correlation coefficient (ICC ± 95%CI, the standard error of measurement (SEM, the smallest detectable difference (SDD, the relative values as % of the grand mean of the SEM and SDD, and the limits of agreement for the intra- and inter-observer '3 repetition average' and the 'highest value of 3 MVPT' knee extension strength measures. Results The intra-observer ICCs were 0.94 for the average of 3 MVPT (95%CI: 0.86–0.97 and 0.86 for the highest value of 3 MVPT (95%CI: 0.71–0.94. The ICCs for the inter-observer measurements were 0.89 for the average of 3 MVPT (95%CI: 0.75–0.95 and 0.77 for the highest value of 3 MVPT (95%CI: 0.54–0.90. The SEMs for the intra-observer measurements were 6.22 Nm (3.98% of the grand mean (GM and 9.83 Nm (5.88% of GM. For the inter-observer measurements, the SEMs were 9.65 Nm (6.65% of GM and 11.41 Nm (6.73% of GM. The SDDs for the generated parameters varied from 17.23 Nm (11.04% of GM to 27.26 Nm (17.09% of GM for intra-observer measurements, and 26.76 Nm (16.77% of GM to 31.62 Nm (18.66% of GM for inter-observer measurements, with similar results for the limits of agreement. Conclusion The results indicate that there is acceptable relative reliability

  5. Improving car passengers' comfort and experience by supporting the use of handheld devices

    NARCIS (Netherlands)

    Veen, S.A.T. van; Hiemstra-van Mastrigt, S.; Kamp, I.; Vink, P.


    Background: There is a demand for interiors to support other activities in a car than controlling the vehicle. Currently, this is the case for the car passengers and-in the future-autonomous driving cars will also facilitate drivers to perform other activities. One of these activities is working wit

  6. Improving car passengers' comfort and experience by supporting the use of handheld devices

    NARCIS (Netherlands)

    Van Veen, S.A.T.; Van Mastrigt, S.; Kamp, I.; Vink, P.


    BACKGROUND: There is a demand for interiors to support other activities in a car than controlling the vehicle. Currently, this is the case for the car passengers and – in the future – autonomous driving cars will also facilitate drivers to perform other activities. One of these activities is working

  7. Evaluation of Malaria Diagnoses Using a Handheld Light Microscope in a Community-Based Setting in Rural Côte d'Ivoire. (United States)

    Coulibaly, Jean T; Ouattara, Mamadou; Keiser, Jennifer; Bonfoh, Bassirou; N'Goran, Eliézer K; Andrews, Jason R; Bogoch, Isaac I


    Portable microscopy may facilitate quality diagnostic care in resource-constrained settings. We compared a handheld light microscope (Newton Nm1) with a mobile phone attachment to conventional light microscopy for the detection of Plasmodium falciparum in a cross-sectional study in rural Côte d'Ivoire. Single Giemsa-stained thick blood film from 223 individuals were prepared and read by local laboratory technicians on both microscopes under 1,000× magnification with oil. Of the 223 samples, 162 (72.6%) were P. falciparum positive, and the overall mean parasite count was 1,392/μL of blood. Sensitivity and specificity of the handheld microscope was 80.2% (95% confidence interval [CI]: 73.1-85.9%) and 100.0% (95% CI: 92.6-100.0%), respectively, with a positive and negative predictive value of 100.0% (95% CI: 96.4-100.0%) and 65.6% (95% CI: 54.9-74.9%), respectively. If sensitivity can be improved, handheld light microscopy may become a valuable public health tool for P. falciparum diagnosis.

  8. Intra- and inter-rater reliability of isometric shoulder extensor and internal rotator strength measurements performed using a hand-held dynamometer. (United States)

    Awatani, Takenori; Morikita, Ikuhiro; Shinohara, Junji; Mori, Seigo; Nariai, Miki; Tatsumi, Yasutaka; Nagata, Akinori; Koshiba, Hiroya


    [Purpose] The purpose of the present study was to establish the intra- and inter-rater reliability of measurement of extensor strength in the maximum shoulder abducted position and internal rotator strength in the 90° abducted and the 90° external rotated position using a hand-held dynamometer. [Subjects and Methods] Twelve healthy volunteers (12 male; mean ± SD: age 19.0 ± 1.1 years) participated in the study. The examiners were two students who had nonclinical experience with a hand-held dynamometer measurement. The examiners and participants were blinded to measurement results by the recorder. Participants in the prone position were instructed to hold the contraction against the ground reaction force, and peak isometric force was recorded using the hand-held dynamometer on the floor. Reliability was determined using intraclass correlation coefficients. [Results] The intra- and inter-rater reliability data were found to be "almost perfect". [Conclusion] This study investigated intra- and inter-rater reliability and reveald high reliability. Thus, the measurement method used in the present study can evaluate muscle strength by a simple measurement technique.

  9. HELP: Handheld Emergency Logistics Program for Generating Structured Requests for Resources in Stressful Conditions (United States)


    pilots using night vision goggles . 8 NATO Y: Technique of marking a landing zone using chemlights strung together in the shape of the letter “Y”. The...monocular Helmet Mounted Displays(HMDs) or night vision goggles may restrict peripheral vision and\\or introduce binocular rivalry (in the case of...Vietnam conflict, from the importance of treating for shock to leveraging helicopters to evacuate the wounded. However, these lessons paid off and

  10. Intraoperative handheld probe for 3D imaging of pediatric benign vocal fold lesions using optical coherence tomography (Conference Presentation) (United States)

    Benboujja, Fouzi; Garcia, Jordan; Beaudette, Kathy; Strupler, Mathias; Hartnick, Christopher J.; Boudoux, Caroline


    Excessive and repetitive force applied on vocal fold tissue can induce benign vocal fold lesions. Children affected suffer from chronic hoarseness. In this instance, the vibratory ability of the folds, a complex layered microanatomy, becomes impaired. Histological findings have shown that lesions produce a remodeling of sup-epithelial vocal fold layers. However, our understanding of lesion features and development is still limited. Indeed, conventional imaging techniques do not allow a non-invasive assessment of sub-epithelial integrity of the vocal fold. Furthermore, it remains challenging to differentiate these sub-epithelial lesions (such as bilateral nodules, polyps and cysts) from a clinical perspective, as their outer surfaces are relatively similar. As treatment strategy differs for each lesion type, it is critical to efficiently differentiate sub-epithelial alterations involved in benign lesions. In this study, we developed an optical coherence tomography (OCT) based handheld probe suitable for pediatric laryngological imaging. The probe allows for rapid three-dimensional imaging of vocal fold lesions. The system is adapted to allow for high-resolution intra-operative imaging. We imaged 20 patients undergoing direct laryngoscopy during which we looked at different benign pediatric pathologies such as bilateral nodules, cysts and laryngeal papillomatosis and compared them to healthy tissue. We qualitatively and quantitatively characterized laryngeal pathologies and demonstrated the added advantage of using 3D OCT imaging for lesion discrimination and margin assessment. OCT evaluation of the integrity of the vocal cord could yield to a better pediatric management of laryngeal diseases.

  11. Handheld analyzer with on-chip molecularly-imprinted biosensors for electrical detection of propofol in plasma samples. (United States)

    Hong, Chien-Chong; Lin, Chih-Chung; Hong, Chian-Lang; Lin, Zi-Xiang; Chung, Meng-Hua; Hsieh, Pei-Wen


    This paper proposes a novel handheld analyzer with disposable lab-on-a-chip technology for the electrical detection of the anesthetic propofol in human plasma samples for clinical diagnoses. The developed on-chip biosensors are based on the conduction of molecularly imprinted polymers (MIPs) that employ label-free electrical detection techniques. Propofol in total intravenous anesthesia is widely used with a target-controlled infusion system. At present, the methods employed for detecting blood propofol concentrations in hospitals comprise high-performance liquid chromatography and ion mobility spectrometry. These conventional instruments are bulky, expensive, and difficult to access. In this study, we developed a novel plastic microfluidic biochip with an on-chip anesthetic biosensor that was characterized for the rapid detection of propofol concentrations. The experimental results revealed that the response time of the developed propofol biosensors was 25s. The specific binding of an MIP to a nonimprinted polymer (NIP) reached up to 560%. Moreover, the detection limit of the biosensors was 0.1μg/mL, with a linear detection range of 0.1-30μg/mL. The proposed disposable microfluidic biochip with an on-chip anesthetic biosensor using MIPs exhibited excellent performance in the separation and sensing of propofol molecules in the human plasma samples. Compared with large-scale conventional instruments, the developed microfluidic biochips with on-chip MIP biosensors present the advantages of a compact size, high selectivity, low cost, rapid response, and single-step detection.

  12. The usefulness and limitations of hand-held refractometers in veterinary laboratory medicine: an historical and technical review. (United States)

    George, Jeanne W.


    Medical hand-held refractometers have been used in veterinary practice since their development in the 1960s. They have become ubiquitous for the measurement of protein and urine solute concentrations because of their rapidity of analysis, ease of use, and relatively low cost. Refraction of light offers advantages for the determination of solute concentrations because the measurement requires no chemical alteration of the specimen. Numerous authors have reported that the results of protein estimation by refractometry for domestic mammals correlate well with those obtained by the biuret method, although others have reported both higher and lower refractometric results compared with biuret results. Major discrepancies between biuret and refractometric results have been reported for avian samples. Some of the variation in reported results may be due to differences in design by refractometer manufacturers. Another possible source may be variation in the biuret reagent mixture and assay conditions. Refractometers also can be used to calculate serum water concentration. A table that converts index of refraction to serum water concentration can be used to convert electrolyte concentration from mmol/L of serum to mmol/L of serum water, a more accurate indicator of effective electrolyte concentration. Refractometers are especially useful for determining urine specific gravity on veterinary samples because they require relatively small sample volumes. Specific gravity continues to be the most common unit for reporting total solids concentration. Some solutes, such as acetone, may cause false increases in specific gravity by refractometry, as they increase refraction but are less dense than water.

  13. Task difficulty and inertial properties of hand-held tools: An assessment of their concurrent effects on precision aiming. (United States)

    Silva, Paula L; Bootsma, Reinoud J; Figueiredo, Priscilla Rezende Pereira; Avelar, Bruna Silva; de Andrade, André Gustavo Pereira; Fonseca, Sérgio T; Mancini, Marisa Cotta


    Aiming hand-held tools at targets in space entails adjustments in the dynamical organization of aiming patterns according to the required precision. We asked whether and how these adjustments are modified by the tool's mass distribution. Twelve participants performed reciprocal aiming movements with a 50-cm long wooden probe. Kinematic patterns of probe movements were used as a window into the behavioral dynamic underlying performance of a reciprocal aiming task. We crossed three levels of task difficulty (IDs 2.8, 4.5 and 6.1) with two types of probe varying in their mass distribution (proximal vs distal loading). Movement duration was affected by task difficulty and probe loading (shorter for larger targets and proximal probe loading). Progressive deviations from a sinusoidal movement pattern were observed as task difficulty increased. Such deviations were more pronounced with proximal probe loading. Results point to a higher degree of non-linearity in aiming dynamics when the probe was loaded proximally, which might reflect employment of additional perceptual-motor processes to control the position of its less stable tip at the vicinity of the targets. More generally, the effects of probe loading on aiming pattern and dynamics suggest that perceptual-motor processes responding to task level constraints are sensitive to, and not independent from, biomechanical, end-effector constraints.

  14. Forest Inventory with Terrestrial LiDAR: A Comparison of Static and Hand-Held Mobile Laser Scanning

    Directory of Open Access Journals (Sweden)

    Sébastien Bauwens


    Full Text Available The application of static terrestrial laser scanning (TLS in forest inventories is becoming more effective. Nevertheless, the occlusion effect is still limiting the processing efficiency to extract forest attributes. The use of a mobile laser scanner (MLS would reduce this occlusion. In this study, we assessed and compared a hand-held mobile laser scanner (HMLS with two TLS approaches (single scan: SS, and multi scan: MS for the estimation of several forest parameters in a wide range of forest types and structures. We found that SS is competitive to extract the ground surface of forest plots, while MS gives the best result to describe the upper part of the canopy. The whole cross-section at 1.3 m height is scanned for 91% of the trees (DBH > 10 cm with the HMLS leading to the best results for DBH estimates (bias of −0.08 cm and RMSE of 1.11 cm, compared to no fully-scanned trees for SS and 42% fully-scanned trees for MS. Irregularities, such as bark roughness and non-circular cross-section may explain the negative bias encountered for all of the scanning approaches. The success of using MLS in forests will allow for 3D structure acquisition on a larger scale and in a time-efficient manner.

  15. Plasma endotoxin activity in kangaroos with oral necrobacillosis (lumpy jaw disease) using an automated handheld testing system. (United States)

    Sotohira, Yukari; Suzuki, Kazuyuki; Sasaki, Haruka; Sano, Tadashi; Tsuchiya, Masakazu; Suzuki, Yohko; Shimamori, Toshio; Tsukano, Kenji; Sato, Ayano; Yokota, Hiroshi; Asakawa, Mitsuhiko


    The aim of the present study was to evaluate the reliability and effectiveness of directly determining endotoxin activity in plasma samples from kangaroos with lumpy jaw disease (LJD, n=15) and healthy controls (n=12). Prior to the present study, the ability of the commercially available automated handheld portable test system (PTS(TM)) to detect endotoxin activity in kangaroo plasma was compared with that of the traditional LAL-kinetic turbidimetric (KT) assay. Plasma samples, which were obtained from endotoxin-challenged cattle, were diluted 1:20 in endotoxin-free water and heated to 80°C for 10 min. The performance of the PTS(TM) was not significantly different from that of the traditional LAL-based assay. The data obtained using PTS(TM) correlated with those using KT (r(2)=0.963, PPTS(TM) is applicable as a simplified system to assess endotoxin activity in macropods. In the present study, we demonstrated the diagnostic value of plasma endotoxin activity in kangaroos with systemic inflammation caused by oral necrobacillosis and identified plasma endotoxin activity as a sensitive marker of systemic inflammation in kangaroos with LJD. Based on ROC curves, we proposed a diagnostic cut-off point for endotoxin activity of >0.22 EU/ml for the identification of LJD. Our results indicate that the assessment of plasma endotoxin activity is a promising diagnostic tool for determining the outcome of LJD in captive macropods.

  16. Test-retest reliabilities of hand-held dynamometer for lower-limb muscle strength in intellectual disabilities. (United States)

    Wuang, Yee-Pay; Chang, Jyh-Jong; Wang, Min-Hung; Lin, Hsiu-Ching


    The primary purpose of this study was to investigate the test-retest reliabilities of hand-held dynamometer (HDD) for measuring lower-limb muscle strength in intellectual disabilities (ID). The other purposes were to: (1) compare the lower-limb muscle strength between children with and without ID; (2) probe the relationship between the muscle forces and agility performance in ID; and (3) explore the factors associated with muscle strength in ID. Sixty-one participants (30 boys and 31 girls; mean age=14.1 ± 3.3 year) were assessed by the HDD using a "make" test. The comparative group consisted of 63 typically developing children (33 boys and 30 girls; mean age=14.9 ± 2.1 year). The ID group demonstrated lower muscle groups than in typically developing group. Except for the ankle plantarflexors (ICC=0.69, SEM=0.72), test-retest analysis showed good intrarater reliability with ICC ranging from 0.81 to 0.96, and intrarater SEM values ranged from 0.40 to 0.57. The HDD has the potential to be a reliable tool for strength measurement in ID. Muscle strength was positively related to agility performance. Regression analysis indicated that height, weight, BMI, and activity level were significant predictors of muscle strength in ID.

  17. Direct and Sensitive Detection of CWA Simulants by Active Capillary Plasma Ionization Coupled to a Handheld Ion Trap Mass Spectrometer. (United States)

    Wolf, Jan-Christoph; Etter, Raphael; Schaer, Martin; Siegenthaler, Peter; Zenobi, Renato


    An active capillary plasma ionization (ACI) source was coupled to a handheld mass spectrometer (Mini 10.5; Aston Labs, West Lafayette, IN, USA) and applied to the direct gas-phase detection and quantification of chemical warfare agent (CWA) related chemicals. Complementing the discontinuous atmospheric pressure interface (DAPI) of the Mini 10.5 mass spectrometer with an additional membrane pump, a quasi-continuous sample introduction through the ACI source was achieved. Nerve agent simulants (three dialkyl alkylphosphonates, a dialkyl phosporamidate, and the pesticide dichlorvos) were detected at low gas-phase concentrations with limits of detection ranging from 1.0 μg/m(3) to 6.3 μg/m(3). Our results demonstrate a sensitivity enhancement for portable MS-instrumentation by using an ACI source, enabling direct, quantitative measurements of volatile organic compounds. Due to its high sensitivity, selectivity, low power consumption (<80 W) and weight (<13 kg), this instrumentation has the potential for direct on-site CWA detection as required by military or civil protection. Graphical Abstract ᅟ.

  18. An ultra compact laser diode source for integration in a handheld point-of-care photoacoustic scanner (United States)

    Kohl, A.; Canal, C.; Laugustin, A.; Rabot, O.


    Photoacoustics is a novel medical imaging technique with high potential for early detection of different diseases such as skin cancer or rheumatology. It is a hybrid modality with pulsed laser light for excitation of the tissue, and ultrasound as response. One of the hurdles for its introduction into the clinic, or even in clinical pilot studies and larger trials, is the bulkiness and price of existing photoacoustic systems. This presentation describes how recent developments in diode laser technology lead to a compact ultrasound scanner with built-in photoacoustic functionality. This is a key for the introduction of photoacoustic technology in the clinic and future point of care systems. We have developed a diode laser system and driver that deliver pulse energies which up to now were only achievable with Nd:YAG lasers. The efficiency and compactness allows integration in a handheld probe. The paper will highlights the laser technology and its radical integration with a medical ultrasound scanner, leading to a first prototype for clinical pilot studies.

  19. Effects of a new mild shampoo for preventing hair loss in Asian by a simple hand-held phototrichogram technique. (United States)

    Baek, J H; Lee, S Y; Yoo, M; Park, W-S; Lee, S J; Boo, Y C; Koh, J-S


    This study was conducted to evaluate the effects of a commercially available shampoo in Korean subjects with alopecia using a simple hand-held phototrichogram technique. Forty-four subjects with alopecia were enrolled and forty subjects continued for 16 weeks. In the test group, total hair counts increased significantly at weeks 8 and 16, and the number of shedding hair significantly decreased at week 16. Terminal hair counts significantly increased at week 8. In the control group, hair thickness and the number of vellus hairs significantly decreased at week 16. The number of total hairs significantly increased in the test group than in the control group at weeks 8 and 16. The number of shedding hairs significantly decreased in the test group than in the control group at week 16. Visual assessment using clinical digital images showed that the number of total hairs appeared to increase although there was no statistical significance. In this study, it was found that the test shampoo could prevent hair loss.

  20. Direct and Sensitive Detection of CWA Simulants by Active Capillary Plasma Ionization Coupled to a Handheld Ion Trap Mass Spectrometer (United States)

    Wolf, Jan-Christoph; Etter, Raphael; Schaer, Martin; Siegenthaler, Peter; Zenobi, Renato


    An active capillary plasma ionization (ACI) source was coupled to a handheld mass spectrometer (Mini 10.5; Aston Labs, West Lafayette, IN, USA) and applied to the direct gas-phase detection and quantification of chemical warfare agent (CWA) related chemicals. Complementing the discontinuous atmospheric pressure interface (DAPI) of the Mini 10.5 mass spectrometer with an additional membrane pump, a quasi-continuous sample introduction through the ACI source was achieved. Nerve agent simulants (three dialkyl alkylphosphonates, a dialkyl phosporamidate, and the pesticide dichlorvos) were detected at low gas-phase concentrations with limits of detection ranging from 1.0 μg/m3 to 6.3 μg/m3. Our results demonstrate a sensitivity enhancement for portable MS-instrumentation by using an ACI source, enabling direct, quantitative measurements of volatile organic compounds. Due to its high sensitivity, selectivity, low power consumption (<80 W) and weight (<13 kg), this instrumentation has the potential for direct on-site CWA detection as required by military or civil protection.

  1. Four dimensional hybrid ultrasound and optoacoustic imaging via passive element optical excitation in a hand-held probe

    Energy Technology Data Exchange (ETDEWEB)

    Fehm, Thomas Felix; Razansky, Daniel, E-mail: [Institute for Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, Neuherberg (Germany); Faculty of Medicine, Technische Universität München, Munich (Germany); Deán-Ben, Xosé Luís [Institute for Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, Neuherberg (Germany)


    Ultrasonography and optoacoustic imaging share powerful advantages related to the natural aptitude for real-time image rendering with high resolution, the hand-held operation, and lack of ionizing radiation. The two methods also possess very different yet highly complementary advantages of the mechanical and optical contrast in living tissues. Nonetheless, efficient integration of these modalities remains challenging owing to the fundamental differences in the underlying physical contrast, optimal signal acquisition, and image reconstruction approaches. We report on a method for hybrid acquisition and reconstruction of three-dimensional pulse-echo ultrasound and optoacoustic images in real time based on passive ultrasound generation with an optical absorber, thus avoiding the hardware complexity of active ultrasound generation. In this way, complete hybrid datasets are generated with a single laser interrogation pulse, resulting in simultaneous rendering of ultrasound and optoacoustic images at an unprecedented rate of 10 volumetric frames per second. Performance is subsequently showcased in phantom experiments and in-vivo measurements from a healthy human volunteer, confirming general clinical applicability of the method.

  2. Prevalence and risk factors associated with musculoskeletal complaints among users of mobile handheld devices: A systematic review. (United States)

    Xie, Yanfei; Szeto, Grace; Dai, Jie


    This systematic review aimed at evaluating the prevalence and risk factors for musculoskeletal complaints associated with mobile handheld device use. Pubmed, Medline, Web of Science, CINAHL and Embase were searched. The methodological quality of included studies was assessed. Strength of evidence for risk factors was determined based on study designs, methodological quality and consistency of results. Five high-quality, eight acceptable-quality and two low-quality peer-reviewed articles were included. This review demonstrates that the prevalence of musculoskeletal complaints among mobile device users ranges from 1.0% to 67.8% and neck complaints have the highest prevalence rates ranging from 17.3% to 67.8%. This study also finds some evidence for neck flexion, frequency of phone calls, texting and gaming in relation to musculoskeletal complaints among mobile device users. Inconclusive evidence is shown for other risk factors such as duration of use and human-device interaction techniques due to inconsistent results or a limited number of studies.

  3. Comparative Variable Temperature Studies of Polyamide II with a Benchtop Fourier Transform and a Miniature Handheld Near-Infrared Spectrometer Using 2D-COS and PCMW-2D Analysis. (United States)

    Unger, Miriam; Pfeifer, Frank; Siesler, Heinz W


    The main objective of this communication is to compare the performance of a miniaturized handheld near-infrared (NIR) spectrometer with a benchtop Fourier transform near-infrared (FT-NIR) spectrometer. Generally, NIR spectroscopy is an extremely powerful analytical tool to study hydrogen-bonding changes of amide functionalities in solid and liquid materials and therefore variable temperature NIR measurements of polyamide II (PAII) have been selected as a case study. The information content of the measurement data has been further enhanced by exploiting the potential of two-dimensional correlation spectroscopy (2D-COS) and the perturbation correlation moving window two-dimensional (PCMW2D) evaluation technique. The data provide valuable insights not only into the changes of the hydrogen-bonding structure and the recrystallization of the hydrocarbon segments of the investigated PAII but also in their sequential order. Furthermore, it has been demonstrated that the 2D-COS and PCMW2D results derived from the spectra measured with the miniaturized NIR instrument are equivalent to the information extracted from the data obtained with the high-performance FT-NIR instrument.

  4. Limitations of Condensed Teaching Strategies to Develop Hand-Held Cardiac Ultrasonography Skills in Internal Medicine Residents. (United States)

    Wilkinson, Jeffrey S; Barake, Walid; Smith, Chris; Thakrar, Amar; Johri, Amer M


    Advances in ultrasonographic technology have allowed for hand-held cardiac ultrasonography (HHCU) units that fit into a physician's laboratory coat. Recently, studies to educate internal medicine residents have shown promise. The optimal duration and methodology for teaching HHCU skills has not been established. Over a 1-year period, internal medicine residents were recruited during their cardiology ward rotation into a single-centre nonblinded randomized trial. The 2 condensed teaching strategies were (1) a conventional ward-based program and (2) a technology-driven simulation-based strategy. Outcomes were evaluated by (1) an objective structured clinical examination (OSCE) to evaluate interpretation ability (assessing both type I and type II error rates) and (2) demonstration of HHCU skills graded by 2 level III echocardiographers. Twenty-four internal medicine residents were randomized. After teaching, the conventional teaching group had a significant absolute increase in the ability to make a singular correct diagnosis (20%; P < 0.001). In the technology arm, making a singular correct diagnosis increased 24% from baseline (P = 0.001). Interpretation skill was not significantly different between groups. The false-positive rate increased by an absolute 14% and 17% in the conventional and technology groups, respectively (P = 0.079 and P = 0.008). Our findings suggest that HHCU interpretation skills improve after either a conventional ward-based or a technology-driven approach. However, our study emphasizes the important limitations of both teaching programs, because we detected a trend toward an increase in the false-positive rate after both approaches. This suggests that a short duration of training may not be sufficient for HHCU to be performed in a safe manner.

  5. Is Hand-Held Optical Coherence Tomography Reliable in Infants and Young Children with and without Nystagmus? (United States)

    Lee, Helena; Proudlock, Frank; Gottlob, Irene


    Purpose To evaluate the reliability of the spectral domain hand-held OCT (HH-OCT) in assessing foveal morphology in children with and without nystagmus. Methods Forty-nine subjects with nystagmus (mean age 43.83 months; range 1-82 months) and 48 controls (mean age 43.02 months; range 0 to 83 months were recruited and scanned using HH-OCT (Bioptigen). A minimum of 2 separate volumetric scans on the same examination day of the fovea were obtained. The images were imported into ImageJ software where manual retinal layer segmentation of the central foveal B-scan was performed. Agreement between scans was assessed by determining the intraclass correlation coefficients (ICC) and Bland–Altman plots. Results Both the nystagmus and controls groups showed an excellent degree of reproducibility between two examinations with ICCs greater than 0.96 for central macular thickness (CMT) and greater than 0.8 for the outer nuclear layer and outer segment of the photoreceptors. The nerve fiber layer, ganglion cell layer, outer plexiform layer, inner segment of the photoreceptors and retinal pigment epithelium were less reliable with ICCs of less than 0.7. There was no difference in the reliability of scans obtained in children with nystagmus as compared to controls and both groups had good inter-eye agreement with ICCs greater than 0.94 for CMT. Conclusion We have shown for the first time that the HH-OCT provides reliable measurements in children with and without nystagmus. This is important as the HH-OCT will have a greater diagnostic and prognostic role in young children with nystagmus and other eye diseases in the future. PMID:24222299

  6. The Fluostick, a real hand-held system for near-infrared fluorescence image-guided surgery (United States)

    Dorval, Paul; Mangeret, Norman; Guillermet, Stephanie; Righini, Christian Adrien; Barabino, Gabriele; Rizo, Philippe; Poulet, Patrick


    Near-infrared fluorescence image-guided surgery, FIGS, has lately shown a huge potential in oncologic and lymphatic related surgeries. In some indications such as liver or heart surgery, fluorescence-reachable anatomic structures are limited by the access to the surgical field. Nevertheless, most of the systems available on the market are too large to image the sides of cavities. Small devices are clearly required to improve workability of fluorescence imaging systems. The current work describes the development of an instrument and the results of its evaluation. In order to image narrow area, we developed a small size device consisting of an optical head connected to a control box. The whole system, optical head, control box and software, receives a CE mark for clinical procedures. Building on existing technologies, we simplified the fluorescence imaging system. It consists of a custom charged-coupled device camera, a high color rendering index visible LED illumination and a Class1 Laser fluorophore excitation. With a curved shape of 25x35x150mm, the optical head was designed as a true hand-held probe. The field of view varies from 5x3.75cm to 2x1.5cm. The device is able to collect and display the signal of 5pmol of IndoCyanine Green (ICG) with a spatial resolution down to 70μm at 25 frames per second. The system has been evaluated in pre-clinical and clinical procedures. The preclinical studies confirmed the ability of the system to visualize tumors in mice models. Clinical evaluations includes lymphedema investigations and surgical resections of tumors in colorectal cancer.

  7. Parafoveal retinal cone mosaic imaging in children with ultra-compact switchable SLO/OCT handheld probe (Conference Presentation) (United States)

    LaRocca, Francesco; Nankivil, Derek; DuBose, Theodore B.; Toth, Cynthia A.; Farsiu, Sina; Izatt, Joseph A.


    In vivo photoreceptor imaging has enhanced the way vision scientists and ophthalmologists understand the retinal structure, function, and etiology of numerous retinal pathologies. However, the complexity and large footprint of current systems capable of resolving photoreceptors has limited imaging to patients who are able to sit in an upright position and fixate for several minutes. Unfortunately, this excludes an important fraction of patients including bedridden patients, small children, and infants. Here, we show that our dual-modality, high-resolution handheld probe with a weight of only 94 g is capable of visualizing photoreceptors in supine children. Our device utilizes a microelectromechanical systems (MEMS) scanner and a novel telescope design to achieve over an order of magnitude reduction in size compared to similar systems. The probe has a 7° field of view and a lateral resolution of 8 µm. The optical coherence tomography (OCT) system has an axial resolution of 7 µm and a sensitivity of 101 dB. High definition scanning laser ophthalmoscopy (SLO) and OCT images were acquired from children ranging from 14 months to 12 years of age with and without pathology during examination under anesthesia in the operating room. Parafoveal cone imaging was shown using the SLO arm of this device without adaptive optics using a 3° FOV for the first time in children under 4 years old. This work lays the foundation for pediatric research, which will improve understanding of retinal development, maldevelopment and early onset of diseases at the cellular level during the beginning stages of human growth.

  8. Measurement of Visual Reaction Times Using Hand-held Mobile Devices (United States)

    Mulligan, Jeffrey B.; Arsintescu, Lucia; Flynn-Evans, Erin


    Modern mobile devices provide a convenient platform for collecting research data in the field. But,because the working of these devices is often cloaked behind multiple layers of proprietary system software, it can bedifficult to assess the accuracy of the data they produce, particularly in the case of timing. We have been collecting datain a simple visual reaction time experiment, as part of a fatigue testing protocol known as the Psychomotor Vigilance Test (PVT). In this protocol, subjects run a 5-minute block consisting of a sequence of trials in which a visual stimulus appears after an unpredictable variable delay. The subject is required to tap the screen as soon as possible after the appearance of the stimulus. In order to validate the reaction times reported by our program, we had subjects perform the task while a high-speed video camera recorded both the display screen, and a side view of the finger (observed in a mirror). Simple image-processing methods were applied to determine the frames in which the stimulus appeared and disappeared, and in which the finger made and broke contact with the screen. The results demonstrate a systematic delay between the initial contact by the finger and the detection of the touch by the software, having a value of 80 +- 20 milliseconds.

  9. The Handheld Library: Developments at the Rector Gabriel Ferraté Library, UPC

    Directory of Open Access Journals (Sweden)

    Beatriz Benítez Juan


    Full Text Available The purpose of this paper is to highlight the mobile services developed by the Rector Gabriel Ferraté Library (BRGF of the Universitat Politècnica de Catalunya (UPC-Barcelona Tech in Barcelona, Spain. We hope this paper will be of use to other libraries exploring new technologies for communicating and delivering their services to users at a time when mobile services are an emerging topic in librarianship and information science literature. By setting out the successive steps involved in the as yet unfinished process of building our mobile services portfolio, we aim to offer a detailed picture of the mobile services and features offered by a university library from a case study perspective. The main topics to be discussed include: The BRGF’s mobile website, including the information available, its interactive capabilities and the services it provides to its users. The mobile-friendly version of UP Commons(the UPC Library Service’s institutional repositories. The UPC Library Service’s mobile OPAC. The mobile version of u-win(BRGF’s videogame service. The use of QR codes to deliver information to mobile devices. Text message notifications. Additional topics for discussion include: The library’s organisation and the organisational concepts that underpin and make possible its technological developments (including mobile. BRGF’s concern regarding the reduction of investment in the development of mobile services. The criteria and tools used to guide the library’s decisions regarding the design and orientation of current and future mobile services. How mobile services can help to improve the image of the library as a leading technology site. Selected mobile features that BRGF plans to offer in the near future. Ultimately, this paper aims to delineate the effectiveness and potential of delivering library services by the preferred means of communication of a new generation of students and teachers.

  10. Clinical effectiveness of the Respimat® inhaler device in managing chronic obstructive pulmonary disease: evidence when compared with other handheld inhaler devices

    Directory of Open Access Journals (Sweden)

    et al


    Full Text Available Felix SF Ram1, Celso R Carvallho2, John White31School of Health and Social Services, Massey University, Auckland, New Zealand; 2Department of Physical Therapy, School of Medicine, University of São Paulo, Brazil; 3York Hospitals NHS Foundation Trust, York Hospital, York, UKObjectives: Medication for the management of chronic obstructive pulmonary disease (COPD may be delivered by a number of different inhaler devices. This study was undertaken to determine the clinical effectiveness of the Respimat® handheld inhaler device compared with other handheld inhaler devices for the delivery of medication in stable COPD.Methodology: A systematic review of high-quality randomized controlled clinical trials comparing Respimat with other inhaler devices using the same medication was performed. Studies were searched for in the Cochrane Central Register of Controlled Trials as well as other relevant electronic databases. Manufacturers of inhaled COPD medication were also contacted for potential trials.Results: Seven studies of high methodological quality with 3813 participants were included in the review. Three trials used Handihaler® as the comparator inhaler, three used a chlorofluorocarbon metered-dose inhaler (CFC-MDI, and one trial used a hydroflouroalkane (HFA-MDI. When Respimat was compared with Handihaler, the following reported outcomes were not significantly different: trough forced expiratory volume in 1 second (FEV1 (weighted mean difference [WMD] 0.01 L; P = 0.14, trough forced vital capacity (FVC (WMD 0.001 L: P = 0.88, peak FEV1 (WMD 0.01 L: P = 0.08, peak FVC (WMD 0.01 L: P = 0.55, morning peak expiratory flow rate (PEFR (WMD 5.06 L/min: P = 0.08, and evening PEFR (WMD 4.39 L/min: P = 0.15. Furthermore, there were no differences when Respimat was compared with Handihaler for risk of exacerbations (relative risk [RR] 0.94: P = 0.81, dry mouth (RR 1.57: P = 0.34, or nasopharyngitis (RR 1.42: P = 0.22. For Respimat compared with CFC-MDI, the

  11. Inactivation of a 25.5 µm Enterococcus faecalis biofilm by a room-temperature, battery-operated, handheld air plasma jet (United States)

    Pei, X.; Lu, X.; Liu, J.; Liu, D.; Yang, Y.; Ostrikov, K.; Chu, Paul K.; Pan, Y.


    Effective biofilm inactivation using a handheld, mobile plasma jet powered by a 12 V dc battery and operated in open air without any external gas supply is reported. This cold, room-temperature plasma is produced in self-repetitive nanosecond discharges with current pulses of ˜100 ns duration, current peak amplitude of ˜6 mA and repetition rate of ˜20 kHz. It is shown that the reactive plasma species penetrate to the bottom layer of a 25.5 µm-thick Enterococcus faecalis biofilm and produce a strong bactericidal effect. This is the thickest reported biofilm inactivated using room-temperature air plasmas.

  12. A handheld high-sensitivity micro-NMR CMOS platform with B-field stabilization for multi-type biological/chemical assays



    We report a micro-nuclear magnetic resonance (NMR) system compatible with multi-type biological/chemical lab-on-a-chip assays. Unified in a handheld scale (dimension: 14 x 6 x 11 cm³, weight: 1.4 kg), the system is capable to detect<100 pM of Enterococcus faecalis derived DNA from a 2.5 μL sample. The key components are a portable magnet (0.46 T, 1.25 kg) for nucleus magnetization, a system PCB for I/O interface, an FPGA for system control, a current driver for trimming the magnetic (B) fi...

  13. Handheld new technology Raman and portable FT-IR spectrometers as complementary tools for the in situ identification of organic materials in modern art (United States)

    Vagnini, M.; Gabrieli, F.; Daveri, A.; Sali, D.


    A non-invasive approach has been carried out to characterize painting materials used in modern artworks conserved in the art collection of Carandente's museum at Palazzo Collicola in Spoleto (Italy). This work is focused on the cross-validation of the handheld BRAVO Raman spectrometer, that uses a sequentially Shifted Excitation (SSE) to mitigate fluorescence, for the characterization specifically of organic materials. The analytical procedure, combining XRF, Raman and reflection infrared spectroscopy, allowed a complete characterization of the artists' palettes; particularly eight different synthetic dyes belonging to the class of pigment red (PR) and pigment yellow (PY.), synthetic and traditional binders, such as alkyd resin and lipids have been easily identified.

  14. 基于PXA322的RFID手持终端的设计%Design of RFID Handheld Terminals Based on PXA322

    Institute of Scientific and Technical Information of China (English)

    李颀; 胡海强


    In view of the low-efficiency situation of the modern inventory management relying on hand-held devices currently, this paper proposed the design of handheld terminals based on the RFID technology and the advanced ARM processor. Using Mifare non-contact reader chip MFRC522 produced by NXP, a Netherlands enterprise, as the core chip, we designed the RFID data acquisition module. Then in order to improve the system for timely and accurate data processing and with regard to standby time, we adopted the PXA322 processor and programmable power management chip as the primary processor in the core components. Through the analysis of PXA322 processor and RFID application in inventory management, we designed and realized the handheld reader system hardware architecture and RFID-driven program design. The result of an experimental study demonstrated that the design could improve the hand-held device's data reading speed and ability to process data.%针对目前手持设备记录货物进出数据在现代库存管理上效率低下的情况,设计一款基于RFID技术和高性能ARM处理器的手持终端.采用荷兰恩智浦公司的Mifare非接触读卡芯片MFRC522为核心芯片,设计RFID数据采集模块.为提高系统对数据及时准确的处理和延长待机时间,采用PXA322作为系统的核心处理器,同时选用可编程电源管理芯片LP3972.在分析研究RFID在库存管理应用的基础上,完成手持读写器系统硬件设计并实现RFID驱动程序的设计.实验结果表明:该设计提高了手持设备数据读取速度和对数据的处理能力.

  15. An assessment of a handheld X-ray fluorescence instrument for use in exploration and development with an emphasis on REEs and related specialty metals (United States)

    Simandl, G. J.; Stone, R. S.; Paradis, S.; Fajber, R.; Reid, H. M.; Grattan, K.


    Handheld (portable) X-ray fluorescence (pXRF) instruments are designed for use in the exploration for base metals, precious metals, and specialty metals (e.g. rare earth elements (REE), Ta, and Nb) and allow rapid decision-making directly in the field. This paper evaluates the technical merits and limitations of pXRF technology in the exploration for specialty metals using data generated from the analysis of three geochemical standards and a silica blank: Standard Reference Material NIST 2780 from the National Institute of Standards and Technology, Gaithersburg; the Certified Reference Material "TRLK" Rare Earth Ore "CGL 124" from the Mongolia Central Geological Laboratory; the Reference Niobium Ore OKA-1 (CANMET); and a silica blank described as Si (IV) oxide (99.8 % on metal basis) from Alpha Aesar (Ward Hill, MA, USA). The data was acquired over a period of nearly 2 years as a by-product of several distinct specialty metal-related projects using the same pXRF instrument and the same settings. Instrumental analytical accuracy was determined using the percent difference (%diff) between the average concentrations of the pXRF instrument readings and the reported certified values of the standard. Percent relative standard deviation (%RSD) was used as a measure of precision. Smaller %diff and %RSD indicate more accurate and precise data, and the accuracy and precision of the pXRF depended strongly on the elemental concentrations in the standards used. Box and whisker diagrams were used to illustrate characteristics of pXRF data sets (mean, lower and upper quartiles, and range) corresponding to individual standards. The bias of the pXRF determinations (under/overestimation) relative to certified values of individual standards are also depicted on these diagrams. This study indicates that the pXRF was capable of producing readings for Si, K, Al, Fe, Ca, Ti, Pb, Zn, Sr, Ag, Cd, Th, Sb, P, S, Mo, Mn, Mg, As, Nb, Rb, La, Ce, Pr, Nd, and Y within 10 %RSD of the reported

  16. Possible Radiation-Induced Damage to the Molecular Structure of Wooden Artifacts Due to Micro-Computed Tomography, Handheld X-Ray Fluorescence, and X-Ray Photoelectron Spectroscopic Techniques

    Directory of Open Access Journals (Sweden)

    Madalena Kozachuk


    Full Text Available This study was undertaken to ascertain whether radiation produced by X-ray photoelectron spectroscopy (XPS, micro-computed tomography (μCT and/or portable handheld X-ray fluorescence (XRF equipment might damage wood artifacts during analysis. Changes at the molecular level were monitored by Fourier transform infrared (FTIR analysis. No significant changes in FTIR spectra were observed as a result of μCT or handheld XRF analysis. No substantial changes in the collected FTIR spectra were observed when XPS analytical times on the order of minutes were used. However, XPS analysis collected over tens of hours did produce significant changes in the FTIR spectra.

  17. Reliability of lower extremity muscle strength measurements with handheld dynamometry in stroke patients during the acute phase: a pilot reliability study. (United States)

    Yen, Hsiao-Ching; Luh, Jer-Junn; Teng, Ting; Pan, Guan-Shuo; Chen, Wen-Shiang; Hsun, Chiang-Chang; Jeng, Jiann-Shing


    [Purpose] No literature has described a suitable method for measuring muscle strength in a supine position during acute phase after stroke. This study investigated the feasibility and reliability of using a commercial handheld dynamometer to measure the muscle strengths of the hip flexor, knee extensor, and dorsiflexor in the supine position with a modified method for patients at a stroke intensive care center within 7 days of stroke onset. [Subjects and Methods] Fifteen persons with acute stroke participated in this cross-sectional study. For each patient, the muscle strengths of the hip flexors, knee extensors, and dorsiflexors were measured twice by two testers on the same day. Each patient was re-tested at the same time of day one day later. Inter-rater and test-retest reliability were then determined by the intraclass correlation coefficients (ICCs). [Results] For the three muscle groups, the inter-rater reliability ICCs were all 0.99 and the test-retest reliability ICCs were greater than 0.85. The investigated method thus has good inter-rater reliability and high agreement between the test-retest measurements, with acceptable measurement errors. [Conclusion] The modified method using a handheld dynamometer to test the muscle strength of acute stroke patients is a feasible and reliable method for clinical use.

  18. Rapid and non-destructive determination of quality parameters in the 'Tommy Atkins' mango using a novel handheld near infrared spectrometer. (United States)

    Marques, Emanuel José Nascimento; de Freitas, Sérgio Tonetto; Pimentel, Maria Fernanda; Pasquini, Celio


    The objective of this study was to evaluate the potential of a new handheld ultra-compact near infrared (NIR) spectrometer, based on the linear-variable filter (LVF) technology for rapid and non-destructive quality control analysis of the 'Tommy Atkins' mango. Multivariate calibration models were built using the Partial Least Squares (PLS) regression method to determine soluble solids (SS), dry matter (DM), titratable acidity (TA) and pulp firmness (PF). Different spectral pre-processing techniques were tested. Coefficient of determination and root mean square errors of prediction (RMSEP) values were, respectively: 0.92 and 0.55°Brix for SS, 0.67 and 0.51% for DM, 0.50 and 0.17% citric acid for TA, 0.72 and 12.2N for PF. The predictive models allowed monitoring physico-chemical changes in each fruit during ripening. The results show the feasibility of using the new NIR handheld spectrometer to determine quality parameters in the 'Tommy Atkins' mango.

  19. MEMS-based handheld scanning probe with pre-shaped input signals for distortion-free images in Gabor-domain optical coherence microscopy. (United States)

    Cogliati, Andrea; Canavesi, Cristina; Hayes, Adam; Tankam, Patrice; Duma, Virgil-Florin; Santhanam, Anand; Thompson, Kevin P; Rolland, Jannick P


    High-speed scanning in optical coherence tomography (OCT) often comes with either compromises in image quality, the requirement for post-processing of the acquired images, or both. We report on distortion-free OCT volumetric imaging with a dual-axis micro-electro-mechanical system (MEMS)-based handheld imaging probe. In the context of an imaging probe with optics located between the 2D MEMS and the sample, we report in this paper on how pre-shaped open-loop input signals with tailored non-linear parts were implemented in a custom control board and, unlike the sinusoidal signals typically used for MEMS, achieved real-time distortion-free imaging without post-processing. The MEMS mirror was integrated into a compact, lightweight handheld probe. The MEMS scanner achieved a 12-fold reduction in volume and 17-fold reduction in weight over a previous dual-mirror galvanometer-based scanner. Distortion-free imaging with no post-processing with a Gabor-domain optical coherence microscope (GD-OCM) with 2 μm axial and lateral resolutions over a field of view of 1 × 1 mm2 is demonstrated experimentally through volumetric images of a regular microscopic structure, an excised human cornea, and in vivo human skin.

  20. Into the Wild: Neuroergonomic Differentiation of Hand-Held and Augmented Reality Wearable Displays during Outdoor Navigation with Functional Near Infrared Spectroscopy. (United States)

    McKendrick, Ryan; Parasuraman, Raja; Murtza, Rabia; Formwalt, Alice; Baccus, Wendy; Paczynski, Martin; Ayaz, Hasan


    Highly mobile computing devices promise to improve quality of life, productivity, and performance. Increased situation awareness and reduced mental workload are two potential means by which this can be accomplished. However, it is difficult to measure these concepts in the "wild". We employed ultra-portable battery operated and wireless functional near infrared spectroscopy (fNIRS) to non-invasively measure hemodynamic changes in the brain's Prefrontal cortex (PFC). Measurements were taken during navigation of a college campus with either a hand-held display, or an Augmented reality wearable display (ARWD). Hemodynamic measures were also paired with secondary tasks of visual perception and auditory working memory to provide behavioral assessment of situation awareness and mental workload. Navigating with an augmented reality wearable display produced the least workload during the auditory working memory task, and a trend for improved situation awareness in our measures of prefrontal hemodynamics. The hemodynamics associated with errors were also different between the two devices. Errors with an augmented reality wearable display were associated with increased prefrontal activity and the opposite was observed for the hand-held display. This suggests that the cognitive mechanisms underlying errors between the two devices differ. These findings show fNIRS is a valuable tool for assessing new technology in ecologically valid settings and that ARWDs offer benefits with regards to mental workload while navigating, and potentially superior situation awareness with improved display design.

  1. Use of handheld X-ray fluorescence as a non-invasive method to distinguish between Asian and African elephant tusks (United States)

    Buddhachat, Kittisak; Thitaram, Chatchote; Brown, Janine L.; Klinhom, Sarisa; Bansiddhi, Pakkanut; Penchart, Kitichaya; Ouitavon, Kanita; Sriaksorn, Khanittha; Pa-in, Chalermpol; Kanchanasaka, Budsabong; Somgird, Chaleamchat; Nganvongpanit, Korakot


    We describe the use of handheld X-ray fluorescence, for elephant tusk species identification. Asian (n = 72) and African (n = 85) elephant tusks were scanned and we utilized the species differences in elemental composition to develop a functional model differentiating between species with high precision. Spatially, the majority of measured elements (n = 26) exhibited a homogeneous distribution in cross-section, but a more heterologous pattern in the longitudinal direction. Twenty-one of twenty four elements differed between Asian and African samples. Data were subjected to hierarchical cluster analysis followed by a stepwise discriminant analysis, which identified elements for the functional equation. The best equation consisted of ratios of Si, S, Cl, Ti, Mn, Ag, Sb and W, with Zr as the denominator. Next, Bayesian binary regression model analysis was conducted to predict the probability that a tusk would be of African origin. A cut-off value was established to improve discrimination. This Bayesian hybrid classification model was then validated by scanning an additional 30 Asian and 41 African tusks, which showed high accuracy (94%) and precision (95%) rates. We conclude that handheld XRF is an accurate, non-invasive method to discriminate origin of elephant tusks provides rapid results applicable to use in the field.

  2. Motion-compensated hand-held common-path Fourier-domain optical coherence tomography probe for image-guided intervention (United States)

    Huang, Yong; Song, Cheol; Liu, Xuan; Kang, Jin U.


    A motion-compensated hand-held common-path Fourier-domain optical coherence tomography imaging probe has been developed for image guided intervention during microsurgery. A hand-held prototype instrument was designed and fabricated by integrating an imaging fiber probe inside a stainless steel needle which is attached to the ceramic shaft of a piezoelectric motor housed in an aluminum handle. The fiber probe obtains A-scan images. The distance information was extracted from the A-scans to track the sample surface distance and a fixed distance was maintained by a feedback motor control which effectively compensated hand tremor and target movements in the axial direction. Graphical user interface, real-time data processing, and visualization based on a CPU-GPU hybrid programming architecture were developed and used in the implantation of this system. To validate the system, free-hand optical coherence tomography images using various samples were obtained. The system can be easily integrated into microsurgical tools and robotics for a wide range of clinical applications. Such tools could offer physicians the freedom to easily image sites of interest with reduced risk and higher image quality.

  3. Hand-Held Keyboard (United States)


    The Data Egg, a prototype chord key-based data entry device, can be used autonomously or as an auxiliary keyboard with a personal computer. Data is entered by pressing combinations of seven buttons positioned where the fingers naturally fall when clasping the device. An experienced user can enter text at 30 to 35 words per minute. No transcription is required. The input is downloaded into a computer and printed. The Data Egg can be used by an astronaut in space, a journalist, a bedridden person, etc. It was developed by a Jet Propulsion Laboratory engineer. Product is not currently manufactured.

  4. Better self-management and meaningful activities thanks to tablets? Development of a person-centered program to support people with mild dementia and their carers through use of hand-held touch screen devices

    NARCIS (Netherlands)

    Kerkhof, Y.J.; Graff, M.J.L.; Bergsma, A.; Vocht, H.H. de; Droes, R.M.


    BACKGROUND: To offer good support to people with dementia and their carers in an aging and Internet society the deployment of hand-held touch screen devices, better known as tablets, and its applications (apps) can be viable and desirable. However, at the moment it is not clear which apps are usable

  5. Performance, usability and comparison of two versions of a new macular vision test: the handheld Radial Shape Discrimination test

    Directory of Open Access Journals (Sweden)

    Jae Y. Ku


    Full Text Available Background Central vision, critical for everyday tasks such as reading and driving, is impacted by age-related changes in the eye and by diseases such as age-related macular degeneration. The detection of changes in macular function is therefore important. The Radial Shape Discrimination (RSD test measures the threshold at which distortions in a radial frequency pattern can be detected and there is evidence that it is more sensitive to macular pathology than visual acuity (VA. It also provides a more quantitative measure of macular function than the commonly available Amsler grid. Recently, handheld versions of the test (hRSD in which stimuli are presented on mobile devices (e.g., Apple iPod Touch, iPhone have been developed. We investigated the characteristics of the hRSD test in healthy participants. Methods Data were collected using both three-alternative forced choice (3AFC and 4AFC versions of the hRSD test, presented on an Apple iPod Touch. For the 3AFC version, data from a single test session were available for 186 (72 male; mean ± SD age 42 ± 17y; range 16–90y healthy participants. Test-retest data were available for subgroups of participants (intra-session: N = 74; tests approximately 2 months apart: N = 30; tests 39 months apart: N = 15. The 3AFC and 4AFC versions were directly compared in 106 participants who also completed a usability questionnaire. Distance and near VA and Pelli Robson Contrast Sensitivity (CS data were collected and undilated fundoscopy performed on the majority of participants. Results Mean (±SD 3AFC hRSD threshold was −0.77 ± 0.14 logMAR, and was statistically significantly correlated with age (Pearson r = 0.35; p < 0.001. The linear regression of hRSD threshold on age had a slope of +0.0026 compared to +0.0051 for near VA (which also correlated with age: r = 0.51; p < 0.001. There were no statistically significant differences in hRSD thresholds for any of the test-retest subgroups. We

  6. A Platform-Independent Plugin for Navigating Online Radiology Cases. (United States)

    Balkman, Jason D; Awan, Omer A


    Software methods that enable navigation of radiology cases on various digital platforms differ between handheld devices and desktop computers. This has resulted in poor compatibility of online radiology teaching files across mobile smartphones, tablets, and desktop computers. A standardized, platform-independent, or "agnostic" approach for presenting online radiology content was produced in this work by leveraging modern hypertext markup language (HTML) and JavaScript web software technology. We describe the design and evaluation of this software, demonstrate its use across multiple viewing platforms, and make it publicly available as a model for future development efforts.

  7. Accuracy of Mobile Phone and Handheld Light Microscopy for the Diagnosis of Schistosomiasis and Intestinal Protozoa Infections in Cote d'Ivoire.

    Directory of Open Access Journals (Sweden)

    Jean T Coulibaly


    Full Text Available Handheld light microscopy using compact optics and mobile phones may improve the quality of health care in resource-constrained settings by enabling access to prompt and accurate diagnosis.Laboratory technicians were trained to operate two handheld diagnostic devices (Newton Nm1 microscope and a clip-on version of the mobile phone-based CellScope. The accuracy of these devices was compared to conventional light microscopy for the diagnosis of Schistosoma haematobium, S. mansoni, and intestinal protozoa infection in a community-based survey in rural Côte d'Ivoire. One slide of 10 ml filtered urine and a single Kato-Katz thick smear from 226 individuals were subjected to the Newton Nm1 microscope and CellScope for detection of Schistosoma eggs and compared to conventional microscopy. Additionally, 121 sodium acetate-acetic acid-formalin (SAF-fixed stool samples were examined by the Newton Nm1 microscope and compared to conventional microscopy for the diagnosis of intestinal protozoa.The prevalence of S. haematobium, S. mansoni, Giardia intestinalis, and Entamoeba histolytica/E. dispar, as determined by conventional microscopy, was 39.8%, 5.3%, 20.7%, and 4.9%, respectively. The Newton Nm1 microscope had diagnostic sensitivities for S. mansoni and S. haematobium infection of 91.7% (95% confidence interval (CI 59.8-99.6% and 81.1% (95% CI 71.2-88.3%, respectively, and specificities of 99.5% (95% CI 97.0-100% and 97.1% (95% CI 92.2-99.1%, respectively. The CellScope demonstrated sensitivities for S. mansoni and S. haematobium of 50.0% (95% CI 25.4-74.6% and 35.6% (95% CI 25.9-46.4%, respectively, and specificities of 99.5% (95% CI 97.0-100% and 100% (95% CI 86.7-100%, respectively. For G. intestinalis and E. histolytica/E. dispar, the Newton Nm1 microscope had sensitivity of 84.0% (95% CI 63.1-94.7% and 83.3% (95% CI 36.5-99.1%, respectively, and 100% specificity.Handheld diagnostic devices can be employed in community-based surveys in resource

  8. Accuracy of Mobile Phone and Handheld Light Microscopy for the Diagnosis of Schistosomiasis and Intestinal Protozoa Infections in Côte d’Ivoire (United States)

    Coulibaly, Jean T.; Ouattara, Mamadou; D’Ambrosio, Michael V.; Fletcher, Daniel A.; Keiser, Jennifer; Utzinger, Jürg; N’Goran, Eliézer K.


    Background Handheld light microscopy using compact optics and mobile phones may improve the quality of health care in resource-constrained settings by enabling access to prompt and accurate diagnosis. Methodology Laboratory technicians were trained to operate two handheld diagnostic devices (Newton Nm1 microscope and a clip-on version of the mobile phone-based CellScope). The accuracy of these devices was compared to conventional light microscopy for the diagnosis of Schistosoma haematobium, S. mansoni, and intestinal protozoa infection in a community-based survey in rural Côte d’Ivoire. One slide of 10 ml filtered urine and a single Kato-Katz thick smear from 226 individuals were subjected to the Newton Nm1 microscope and CellScope for detection of Schistosoma eggs and compared to conventional microscopy. Additionally, 121 sodium acetate-acetic acid-formalin (SAF)-fixed stool samples were examined by the Newton Nm1 microscope and compared to conventional microscopy for the diagnosis of intestinal protozoa. Principal Findings The prevalence of S. haematobium, S. mansoni, Giardia intestinalis, and Entamoeba histolytica/E. dispar, as determined by conventional microscopy, was 39.8%, 5.3%, 20.7%, and 4.9%, respectively. The Newton Nm1 microscope had diagnostic sensitivities for S. mansoni and S. haematobium infection of 91.7% (95% confidence interval (CI) 59.8–99.6%) and 81.1% (95% CI 71.2–88.3%), respectively, and specificities of 99.5% (95% CI 97.0–100%) and 97.1% (95% CI 92.2–99.1%), respectively. The CellScope demonstrated sensitivities for S. mansoni and S. haematobium of 50.0% (95% CI 25.4–74.6%) and 35.6% (95% CI 25.9–46.4%), respectively, and specificities of 99.5% (95% CI 97.0–100%) and 100% (95% CI 86.7–100%), respectively. For G. intestinalis and E. histolytica/E. dispar, the Newton Nm1 microscope had sensitivity of 84.0% (95% CI 63.1–94.7%) and 83.3% (95% CI 36.5–99.1%), respectively, and 100% specificity. Conclusions

  9. 基于Android的定位追踪APP的设计与实现%The Design of Simple Hand-held Tracking APP Based on Android

    Institute of Scientific and Technical Information of China (English)

    葛欣; 蔺雪葳; 王依岳


    针对手持定位追踪器便携及操作方面的缺陷,本文设计了基于Android的追踪器手机客户端APP。从定位系统的完整性出发,介绍了追踪系统的工作原理、服务器端数据处理机制、手机APP工作流程,以及调用百度地图显示定位器位置的原理和流程。%Defect Tracker for portable hand-held and operated, this article is designed based on Android tracking client APP, from the integrity of the positioning system, the working principle of the tracking system, server-side data processing mechanism, the mobile phone APP workflow and call Baidu map shows the location of the vehicle the principles and processes.

  10. Preliminary validation of handheld X-ray fluorescence spectrometry: distinguishing osseous and dental tissue from nonbone material of similar chemical composition. (United States)

    Zimmerman, Heather A; Schultz, John J; Sigman, Michael E


    One of the tasks of a forensic anthropologist is to sort human bone fragments from other materials, which can be difficult when dealing with highly fragmented and taphonomically modified material. The purpose of this research is to develop a method using handheld X-ray fluorescence (HHXRF) spectrometry to distinguish human and nonhuman bone/teeth from nonbone materials of similar chemical composition using multivariate statistical analyses. The sample materials were derived primarily from previous studies: human bone and teeth, nonhuman bone, nonbiological materials, nonbone biological materials, and taphonomically modified materials. The testing included two phases, testing both the reliability of the instrument and the accuracy of the technique. The results indicate that osseous and dental tissue can be distinguished from nonbone material of similar chemical composition with a high degree of accuracy (94%). While it was not possible to discriminate rock apatite and synthetic hydroxyapatite from bone/teeth, this technique successfully discriminated ivory and octocoral.

  11. Elemental Analysis of Bone, Teeth, Horn and Antler in Different Animal Species Using Non-Invasive Handheld X-Ray Fluorescence.

    Directory of Open Access Journals (Sweden)

    Kittisak Buddhachat

    Full Text Available Mineralized tissues accumulate elements that play crucial roles in animal health. Although elemental content of bone, blood and teeth of human and some animal species have been characterized, data for many others are lacking, as well as species comparisons. Here we describe the distribution of elements in horn (Bovidae, antler (Cervidae, teeth and bone (humerus across a number of species determined by handheld X-ray fluorescence (XRF to better understand differences and potential biological relevance. A difference in elemental profiles between horns and antlers was observed, possibly due to the outer layer of horns being comprised of keratin, whereas antlers are true bone. Species differences in tissue elemental content may be intrinsic, but also related to feeding habits that contribute to mineral accumulation, particularly for toxic heavy metals. One significant finding was a higher level of iron (Fe in the humerus bone of elephants compared to other species. This may be an adaptation of the hematopoietic system by distributing Fe throughout the bone rather than the marrow, as elephant humerus lacks a marrow cavity. We also conducted discriminant analysis and found XRF was capable of distinguishing samples from different species, with humerus bone being the best source for species discrimination. For example, we found a 79.2% correct prediction and success rate of 80% for classification between human and non-human humerus bone. These findings show that handheld XRF can serve as an effective tool for the biological study of elemental composition in mineralized tissue samples and may have a forensic application.

  12. 手持投影机温度测试讨论%Discussion on Temperature Test Case for Handheld Pico-Projector

    Institute of Scientific and Technical Information of China (English)

    贺臻; 冯小波; 施旭; 李荣玉


    手持投影机低电压、低功耗,便于随身携带,散热设计时要考虑到人体可接触温度这一安全性因素.IEC 60065和IEC 60950安全规范标准对于人体最高可接触温度的限值规定不同,文章例举实验测试数据,分别依据这两种安全规范标准对温度测试实验结果进行判定,对手持投影机申请CE认证采用哪种安全规范标准符合声明提供建议.

  13. Design of hand-held digital oscilloscope based on FPGA%基于 FPGA 的手持式数字示波器的设计∗

    Institute of Scientific and Technical Information of China (English)

    朱詠筠; 易艺; 郝建卫; 李俊凯; 王奕澄


    According to the weakness of traditional oscilloscope problems such as large volume and inconvenience,the project base on FPGA (Field Programmable Gate Array ) strong performance to develop a hand-held digital oscilloscope.The system use Altera FPGA as the main control chip to design a logic control circuit.And it use the Quartus II development tools and Verilog HDL language to describe the functions such as control logic, clock distribution,sampling buffer,trigger,frequency and amplitude measuring,etc.System design the SOPC Builder to build the Nios II soft core processor,and it through the C language programming to realize the touch control,display control functions.The test result shows that the oscilloscope system work is stable,and it has high performance and practicality.The project has reference value in the research of the hand-held digital oscilloscope.%针对传统示波器体积大、携带不便等问题,利用现场可编程门阵列(field programmable gate array,FPGA)强大的性能,研制一款基于 FPGA 的手持式数字示波器。系统以 Altera 公司 FPGA 为主控芯片组建逻辑控制电路,利用 Quartus II 开发工具以及 Verilog HDL 语言描述控制逻辑,实现时钟分配、采样缓冲、触发、测频、测幅等功能。用SOPC Builder 构建 Nios II 软核处理器,通过 C 语言编程实现触摸控制、显示控制等功能。经过实验测试表明,该示波器系统工作稳定,具有较高的性能指标和实用性,在手持式数字示波器的研制方面有较好的参考价值。

  14. Design of Handheld Wire Rope Laser Cutting System%手提式钢缆激光切割系统的设计

    Institute of Scientific and Technical Information of China (English)

    何琼; 杨晟; 王英


    This article mainly introduce a handheld laser cutting system for wire rope which used for fiber transferring. By the use of pulsed solid laser,we chose fibers as flexible transmission, designed a special clamping apparatus for rope cutting. Furthermore, we also did some research on its cutting technologies. With the optimized discharge current, pulsed frequency, pulsed width and assisted gas pressure, this system now can meet cutting requirements up to diameter 12 mm wire rope which affords a new approach to rope cutting field.%介绍了一种手提式光纤传输钢缆激光切割系统.以脉冲固体激光器作为光源,采用光纤进行柔性传输,设计了切割钢缆的专用夹具,研究了钢缆的切割工艺.通过优化放电电流、脉冲频率、脉冲宽度、辅助气压等参数,该系统可满足直径12 mm内的钢缆的切割要求,提供了切割钢缆的新方法.

  15. Handheld nonlinear microscope system comprising a 2 MHz repetition rate, mode-locked Yb-fiber laser for in vivo biomedical imaging. (United States)

    Krolopp, Ádám; Csákányi, Attila; Haluszka, Dóra; Csáti, Dániel; Vass, Lajos; Kolonics, Attila; Wikonkál, Norbert; Szipőcs, Róbert


    A novel, Yb-fiber laser based, handheld 2PEF/SHG microscope imaging system is introduced. It is suitable for in vivo imaging of murine skin at an average power level as low as 5 mW at 200 kHz sampling rate. Amplified and compressed laser pulses having a spectral bandwidth of 8 to 12 nm at around 1030 nm excite the biological samples at a ~1.89 MHz repetition rate, which explains how the high quality two-photon excitation fluorescence (2PEF) and second harmonic generation (SHG) images are obtained at the average power level of a laser pointer. The scanning, imaging and detection head, which comprises a conventional microscope objective for beam focusing, has a physical length of ~180 mm owing to the custom designed imaging telescope system between the laser scanner mirrors and the entrance aperture of the microscope objective. Operation of the all-fiber, all-normal dispersion Yb-fiber ring laser oscillator is electronically controlled by a two-channel polarization controller for Q-switching free mode-locked operation. The whole nonlinear microscope imaging system has the main advantages of the low price of the fs laser applied, fiber optics flexibility, a relatively small, light-weight scanning and detection head, and a very low risk of thermal or photochemical damage of the skin samples.

  16. Hand-held echocardiography in the setting of pre-operative cardiac evaluation of patients undergoing non-cardiac surgery: results from a randomized pilot study. (United States)

    Cavallari, Ilaria; Mega, Simona; Goffredo, Costanza; Patti, Giuseppe; Chello, Massimo; Di Sciascio, Germano


    Transthoracic echocardiography is not a routine test in the pre-operative cardiac evaluation of patients undergoing non-cardiac surgery but may be considered in those with known heart failure and valvular heart disease or complaining cardiac symptoms. In this setting, hand-held echocardiography (HHE) could find a potential application as an alternative to standard echocardiography in selected patients; however, its utility in this context has not been investigated. The aim of this pilot study was to evaluate the conclusiveness of HHE compared to standard echocardiography in this subset of patients. 100 patients scheduled for non-cardiac surgery were randomized to receive a standard exam with a Philips Ie33 or a bedside evaluation with a pocket-size imaging device (Opti-Go, Philips Medical System). The primary endpoint was the percentage of satisfactory diagnosis at the end of the examination referred as conclusiveness. Secondary endpoints were the mean duration time and the mean waiting time to perform the exams. No significant difference in terms of conclusiveness between HHE and standard echo was found (86 vs 96%; P = 0.08). Mean duration time of the examinations was 6.1 ± 1.2 min with HHE and 13.1 ± 2.6 min with standard echocardiography (P cardiac surgery, since it provided similar information but it was faster and earlier performed compared to standard echocardiography.

  17. The use of hand-held 35 mm color infrared imagery for estimates of suspended solids - A progress report. [in water pollution monitoring (United States)

    Miller, W. F.; Whisler, F. D.; Robinette, H. R.; Finnie, D.; Cannon, T.


    A cost-effective aerial surveillance technique is proposed for detection and identification of suspended solids which would be operational for both governmental monitoring organizations and private individuals operating catfish farms. Sixteen catfish ponds were flown daily for seven days using two hand-held 35 mm cameras with both Kodachrome X and Ektachrome infrared film. Hue, value, and chroma designations were recorded for each pond on each date by three interpreters, and the accepted color was that recorded by at least two of the interpreters, or if there was a three hue range, the median was accepted. Relations between suspended solids and color designations were analyzed graphically, and chroma was discarded due to an apparent lack of correlation. The data obtained were then analyzed by multiple regression. Significant correlations were revealed between hue and value and total and inorganic suspended solids. If perfected, this technique could be developed to sufficent accuracy for large-scale reconnaissance surveys to monitor the quality of rivers and streams.

  18. Large-area, uniform and low-cost dual-mode plasmonic naked-eye colorimetry and SERS sensor with handheld Raman spectrometer. (United States)

    Xu, Zhida; Jiang, Jing; Wang, Xinhao; Han, Kevin; Ameen, Abid; Khan, Ibrahim; Chang, Te-Wei; Liu, Gang Logan


    We demonstrated a highly-sensitive, wafer-scale, highly-uniform plasmonic nano-mushroom substrate based on plastic for naked-eye plasmonic colorimetry and surface-enhanced Raman spectroscopy (SERS). We gave it the name FlexBrite. The dual-mode functionality of FlexBrite allows for label-free qualitative analysis by SERS with an enhancement factor (EF) of 10(8) and label-free quantitative analysis by naked-eye colorimetry with a sensitivity of 611 nm RIU(-1). The SERS EF of FlexBrite in the wet state was found to be 4.81 × 10(8), 7 times stronger than in the dry state, making FlexBrite suitable for aqueous environments such as microfluid systems. The label-free detection of biotin-streptavidin interaction by both SERS and colorimetry was demonstrated with FlexBrite. The detection of trace amounts of the narcotic drug methamphetamine in drinking water by SERS was implemented with a handheld Raman spectrometer and FlexBrite. This plastic-based dual-mode nano-mushroom substrate has the potential to be used as a sensing platform for easy and fast analysis in chemical and biological assays.

  19. Large-area, uniform and low-cost dual-mode plasmonic naked-eye colorimetry and SERS sensor with handheld Raman spectrometer

    CERN Document Server

    Xu, Zhida; Wang, Xinhao; Han, Kevin; Ameen, Abid; Khan, Ibrahim; Chang, Te-Wei; Liu, Gang Logan


    We demonstrated a highly sensitive, waferscale, highly uniform plasmonic nanomushroom substrate based on plastic for nakedeye plasmonic colorimetry and surface enhanced Raman spectroscopy (SERS). We gave it the name FlexBrite. The dualmode functionality of FlexBrite allows for label-free qualitative analysis by SERS with an enhancement factor (EF) of 10^8 and labelfree quantitative analysis by naked eye colorimetry with a sensitivity of 611 nm RIU-1. The SERS EF of FlexBrite in the wet state was found to be 4.81 X 10^8, 7 times stronger than in the dry state, making FlexBrite suitable for aqueous environments such as microfluid systems. The labelfree detection of biotin streptavidin interaction by both SERS and colorimetry was demonstrated with FlexBrite. The detection of trace amounts of the narcotic drug methamphetamine in drinking water by SERS was implemented with a handheld Raman spectrometer and FlexBrite. This plastic based dual-mode nano-mushroom substrate has the potential to be used as a sensing pla...

  20. Reliability of Isometric Knee Extension Muscle Strength Measurements of Healthy Elderly Subjects Made with a Hand-held Dynamometer and a Belt. (United States)

    Katoh, Munenori; Isozaki, Koji


    [Purpose] The purpose of this study was to examine the reliability of three isometric knee extension strength measurements (IKE) made with a hand-held dynamometer (HHD) and a belt of healthy elderly living in the community as subjects. [Subjects] The subject cohort consisted of 186 healthy elderly people, aged 65 to 79 years, living in local communities. [Methods] IKE of the leg subjects used to kick a ball was measured. IKE of each subject was measured three times using an HHD-belt at intervals of 30 seconds. The reliability of the larger of the first two measurements (LV2) as well as the third measurement (3V) was investigated. [Results] The intraclass correlation coefficients [ICC (1, 1)] for LV2 and 3V were 0.955. Bland-Altman analysis showed a fixed bias, and the limits of agreement ranged from -5.6 to 4.6. [Conclusion] The ICC results show that the test-retest reproducibility of IKE measurements of healthy elderly subjects using an HHD-belt is high. However, Bland-Altman analysis showed a fixed bias, suggesting the need for three measurements.

  1. SEMICONDUCTOR INTEGRATED CIRCUITS: A fully integrated UHF RFID reader SoC for handheld applications in the 0.18 μm CMOS process (United States)

    Jingchao, Wang; Chun, Zhang; Zhihua, Wang


    A low cost fully integrated single-chip UHF radio frequency identification (RFID) reader SoC for short distance handheld applications is presented. The SoC integrates all building blocks—including an RF transceiver, a PLL frequency synthesizer, a digital baseband and an MCU—in a 0.18 μm CMOS process. A high-linearity RX front-end is designed to handle the large self-interferer. A class-E power amplifier with high power efficiency is also integrated to fulfill the function of a UHF passive RFID reader. The measured maximum output power of the transmitter is 20.28 dBm and the measured receiver sensitivity is -60 dBm. The digital baseband including MCU core consumes 3.91 mW with a clock of 10 MHz and the analog part including power amplifier consumes 368.4 mW. The chip has a die area of 5.1 × 3.8 mm2 including pads.

  2. The Use of Handheld X-Ray Fluorescence (XRF) Technology in Unraveling the Eruptive History of the San Francisco Volcanic Field, Arizona (United States)

    Young, Kelsey E.; Evans, C. A.; Hodges, K. V.


    While traditional geologic mapping includes the examination of structural relationships between rock units in the field, more advanced technology now enables us to simultaneously collect and combine analytical datasets with field observations. Information about tectonomagmatic processes can be gleaned from these combined data products. Historically, construction of multi-layered field maps that include sample data has been accomplished serially (first map and collect samples, analyze samples, combine data, and finally, readjust maps and conclusions about geologic history based on combined data sets). New instruments that can be used in the field, such as a handheld xray fluorescence (XRF) unit, are now available. Targeted use of such instruments enables geologists to collect preliminary geochemical data while in the field so that they can optimize scientific data return from each field traverse. Our study tests the application of this technology and projects the benefits gained by real-time geochemical data in the field. The integrated data set produces a richer geologic map and facilitates a stronger contextual picture for field geologists when collecting field observations and samples for future laboratory work. Real-time geochemical data on samples also provide valuable insight regarding sampling decisions by the field geologist

  3. Between-rater reliability of the 6-minute walk test, berg balance scale, and handheld dynamometry in people with multiple sclerosis. (United States)

    Toomey, Elaine; Coote, Susan


    This study investigated the between-rater reliability of the Berg Balance Scale (BBS), 6-Minute Walk test (6MW), and handheld dynamometry (HHD) in people with multiple sclerosis (MS). Previous studies that examined BBS and 6MW reliability in people with MS have not used more than two raters, or analyzed different mobility levels separately. The reliability of HHD has not been previously reported for people with MS. In this study, five physical therapists assessed eight people with MS using the BBS, 6MW, and HHD, resulting in 12 pairs of data. Data were analyzed using intraclass correlation coefficients (ICCs), Spearman correlation coefficients (SCCs), and Bland and Altman methods. The results suggest excellent agreement for the BBS (SCC = 0.95, mean difference between raters [d̄] = 2.08, standard error of measurement [SEM] = 1.77) and 6MW (ICC = 0.98, d̄ = 5.22 m, SEM = 24.76 m) when all mobility levels are analyzed together. Reliability is lower in less mobile people with MS (BBS SCC = 0.6, d̄ = -1.83; 6MW ICC = 0.95, d̄ = 20.04 m). Although the ICC and SCC results for HHD suggest good-to-excellent reliability (0.65-0.85), d̄ ranges up to 17.83 N, with SEM values as high as 40.95 N. While the small sample size is a limitation of this study, the preliminary evidence suggests strong agreement between raters for the BBS and 6MW and decreased agreement between raters for people with greater mobility problems. The mean differences between raters for HHD are probably too high for it to be applied in clinical practice.

  4. Research into Fruit Battery by Handheld Sensor%利用手持技术对水果电池的实验探究

    Institute of Scientific and Technical Information of China (English)



    Therough exploring the fruit battery by handheld sensor, the different types of fruit battery consisted by fruit and the metal electrode were studied. In order to getting the best experimental conditions, the composition of the fruit battery electrodes, electrode spacing, depth electrode inserted in the fruits and the battery connection conditions were carried out experiments. The results showed that fruits containing plenty of tartaric acid, the greater the metal reactivity between the two electrodes and the smaller the distance of the two electrodes, the better the effect of fruit battery was. Serial or parallel were conductive to increasing the voltage of fruit battery, but were not multiplied.%通过手持技术对水果电池进行探究,研究不同种类水果与金属电极组成的水果电池,围绕组成水果电池所使用的电极、电极间距、电极在水果中插入的深度和连接方式等条件展开实验,得到了最佳的实验条件:含果酸丰富的水果,两电极之间的金属活泼性相差越大,两电极间距离越小,其组成的水果电池效果越好,串联或并联都有利于增大水果电池的电压,但都不是成倍增加的。


    Energy Technology Data Exchange (ETDEWEB)

    Lorier, T.


    SRNL’s validation of ANSI N42.34-D6 for the Domestic Nuclear Detection Office (DNDO) was performed utilizing one hand-held instrument (or RID) – the FLIR identiFINDER 2. Each section of the standard was evaluated via a walk-through or test. NOTE: In Table 1, W = walk-through and T = test, as directed by the Domestic Nuclear Detection Office (DNDO). For a walk-through, the experiment was either setup or reviewed for setup; for a test, the N42.34-D6 procedures were followed with some exceptions and comments noted. SRNL is not fully able to evaluate a RID against Sections 7 (Environmental), 8 (Electromagnetic), and 9 (Mechanical) of N42.34, so those portions of this validation were done in collaboration with Qualtest, Inc. in Orlando, Florida. The walk-throughs and tests of Sections 7, 8, and 9 were performed in Qualtest, Inc. facilities with SRNL providing radiological sources as necessary. Where applicable, assessment results and findings of the walk-throughs and tests were recorded on datasheets and a validation summary is provided. A general comment pertained to test requirements found in another standard and referenced in N42.34-D6. For example, step 1 of the test method in section 8.1.2 states “RF test set up information can be found in IEC 61000-4-3.” It is recommended that any information from other standards necessary for conducting the tests within N42.34 should be posted in N42.34 for simplicity and to prevent the user from having to peruse other documents. Another general comment, as noted by Qualtest, is that a tolerance reference is not listed for each test in sections 7-9. Overall, the N42.34-D6 was proven to be practicable, but areas for improvement and recommendations were identified for consideration prior to final ballot submittal.

  6. Application of handheld GPS to grassland resource investigation and mapping%手持GPS在草原调查与制图中的应用

    Institute of Scientific and Technical Information of China (English)

    王大为; 赵军; 付鹏; 师银芳; 杨东辉


    Global Positioning System (GPS) is a much rapid development information technology system, and its application areas have transferred into the daily production and life from the initial high-end military area. Application of GPS technology to grassland survey is the trend of digitization and informatization of grassland survey. This study introduced the application of the Trimble Juno SB handheld receiver in the process of grassland survey at the various stages, and summarized and generalized the technology and method in grassland investigation and mapping, which would provide the information for grassland resource investigation and mapping by GIS technology.%全球定位系统(GPS)是当代发展非常迅速的信息技术系统,运用领域也由最初的高端军事领域深入到日常的生产生活中。运用GPS技术进行草原调查,是草原调查数字化、信息化的趋势。本研究介绍了Trimble Juno SB手持机在草原调查中各阶段的应用,系统地总结归纳了手持GPS在草原调查与制图中的应用技术和方法,为应用GPS技术开展草原资源调查与制图工作提供参考。

  7. A hand-held bus charging and information statistics system%一种手持式公交车收费及信息统计装置

    Institute of Scientific and Technical Information of China (English)

    叶鼎晟; 张凯


    A hand-held bus charging and information statistics system is presented, according to passengers ride the journey to collect fees, instead of the traditional sectional charge, it mainly used for counting recent number of Passengers and each station number of getting on and off. By the wireless data transmission module, the information can be sent to platform as reference for waiting passengers. This kind of device makes public travel conveniently because of the compatibility of existing public transit card. The device can store and Summarize passenger information in the bus. Based on the Analysis of traffic flow and passengers flow information, it is also convenient for Bus Company to dispatch and count.%提出了一种手持式公交车收费及信息统计装置,根据乘客所乘坐路程来进行收费,而不是传统的分段式收费,同时可以统计各站上车人数,每站的下车人数以及目前车内人数等;然后通过无线数据传输模块还可以把车上的信息发送到站台上供等车的乘客参考,并且这种装置对于现存的公交卡也能进行读写,为市民绿色出行提供便利。此种装置能将公交车上的客流信息进行储存、汇总,通过对车流、人流的信息进行分析,还能方便公交车公司进行调度和统计。

  8. Repurposed automated handheld counter as a point-of-care tool to identify individuals 'at risk' of serious post-ivermectin encephalopathy.

    Directory of Open Access Journals (Sweden)

    Sasisekhar Bennuru


    Full Text Available Administration of ivermectin (IVM as part of mass drug administration (MDA campaigns for onchocerciasis and/or lymphatic filariasis (LF has been suspended in areas co-endemic for Loa loa due to severe post-treatment adverse events (SAEs associated with high-burden of infection (>30,000 mf/ml. One simple approach for preventing SAEs is to identify and exclude individuals at risk from MDA. Here, we describe a repurposed hand-held automated cell counter (Scepter 2.0; HHAC as a rapid, point-of-care method for quantifying microfilariae (mf in the blood of infected individuals.The quantification of microfilarial levels in blood of naturally infected humans, experimentally infected baboons, or mf-spiked human blood was tested using a microfluidic-based automated counter and compared to traditional calibrated thick-smears. We demonstrate that mf can be quantified in 20 µl of whole blood following lysis with 10% saponin within a minute of obtaining blood. There was a highly significant concordance between the counts obtained by the HHAC and those by microscopy for mf densities of >5,000 (p30,000 per ml (p<0.0001, r(c = 0.90. Preliminary proof of concept field studies in Cameroon with 20 µl of blood from L. loa infected humans (n = 22 and baboons (n = 4 also demonstrated a significantly high concordance (p<0.0001, r(c = 0.89 with calibrated thick blood smears counts.A repurposed HHAC is a portable, sensitive, rapid, point-of-care and quantitative tool to identify individuals with high levels of L. loa mf that put them at risk for SAEs following MDA. In addition, it provides ease of data storage and accessibility.

  9. Performance comparison of two Olympus InnovX handheld x-ray analyzers for feasibility of measuring arsenic in skin in vivo - Alpha and Delta models. (United States)

    Desouza, E D; Gherase, M R; Fleming, D E B; Chettle, D R; O'Meara, J M; McNeill, F E


    The Figure-Of-Merit (FOM) performance, a combination of detection limit and dose, is compared between two generations of handheld X-Ray Fluorescence (XRF) spectrometers for the feasibility of in vivo XRF measurement of arsenic (As) in skin. The Olympus InnovX Delta model analyzer (40 kVp using either 37 or 17μA) was found to show improvements in Minimum Detection Limit (MDL) using arsenic As-doped skin calibration phantoms with bulk tissue backing, when compared to the first generation InnovX Alpha model (40kVp, 20μA) in 120s measurements. Differences between two different definitions of MDL are discussed. On the Delta system, an MDL of (0.462±0.002) μg/g As was found in phantoms, with a nylon backing behind to mimic bulk tissue behind skin. The equivalent and effective doses were found to be (10±2) mSv and ~7×10(-3)μSv respectively for the Alpha and (15±4) mSv and ~8×10(-3)μSv respectively for the Delta system in 120s exposures. Combining MDL and effective dose, a lower (better) FOM was found for the Delta, (1.7±0.4) ppm mSv(1/2), compared to (4.4±0.5) ppm mSv(1/2) for the Alpha model system. The Delta analyzer demonstrates improved overall system performance for a rapid 2-min measurement in As skin phantoms, such that it can be considered for use in populations exposed to arsenic.

  10. Reliability of hand-held dynamometry for measurement of lower limb muscle strength in children with Duchenne and Becker muscular dystrophy

    Directory of Open Access Journals (Sweden)

    Wei SHI


    Full Text Available Objective To determine the reliability of hand-held dynamometry (HHD for lower limb isometric muscle strength measurement in children with Duchenne and Becker muscular dystrophy (DMD/BMD.  Methods A total of 21 children [20 males and one female; mean age was (7.88 ± 2.87 years, ranging between 3.96-14.09 years; mean age at diagnosis was (5.88 ± 2.88 years, ranging between 1.35-12.89 years; mean height was (120.64 ± 16.30 cm, ranging between 97-153 cm; mean body weight was (24.62 ± 9.05 kg, ranging between 14-50 kg] with DMD (19/21 and BMD (2/21 were involved from Rehabilitation Center of Children's Hospital of Fudan University. The muscle strength of hip, knee and ankle was measured by HHD under standardized test methods. The test-retest results were compared to determine the inter-test reliability, and the results among testers were compared to determine the inter-tester reliability.  Results HHD showed fine inter-tester reliability (ICC = 0.762-0.978 and inter-test reliability (ICC = 0.690-0.938 in measuring lower limb muscle strength of children with DMD/BMD. Results also showed relatively poor reliability in distal muscle groups (foot plantar flexion and dorsiflexion.  Conclusions HHD, showing fine inter-tester and inter-test reliability in measuring the lower limb muscle strength of children with DMD/BMD, can be used in monitoring muscle strength changing and assessing effects of clinical interventions. DOI: 10.3969/j.issn.1672-6731.2015.05.009

  11. An Approach to Precise Nitrogen Management Using Hand-Held Crop Sensor Measurements and Winter Wheat Yield Mapping in a Mediterranean Environment

    Directory of Open Access Journals (Sweden)

    Lucía Quebrajo


    Full Text Available Regardless of the crop production system, nutrients inputs must be controlled at or below a certain economic threshold to achieve an acceptable level of profitability. The use of management zones and variable-rate fertilizer applications is gaining popularity in precision agriculture. Many researchers have evaluated the application of final yield maps and geo-referenced geophysical measurements (e.g., apparent soil electrical conductivity-ECa as a method of establishing relatively homogeneous management zones within the same plot. Yield estimation models based on crop conditions at certain growth stages, soil nutrient statuses, agronomic factors, moisture statuses, and weed/pest pressures are a primary goal in precision agriculture. This study attempted to achieve the following objectives: (1 to investigate the potential for predicting winter wheat yields using vegetation measurements (the Normalized Difference Vegetation Index—NDVI at the beginning of the season, thereby allowing for a yield response to nitrogen (N fertilizer; and (2 evaluate the feasibility of using inexpensive optical sensor measurements in a Mediterranean environment. A field experiment was conducted in two commercial wheat fields near Seville, in southwestern Spain. Yield data were collected at harvest using a yield monitoring system (RDS Ceres II-volumetric meter installed on a combine. Wheat yield and NDVI values of 3498 ± 481 kg ha−1 and 0.67 ± 0.04 nm nm−1 (field 1 and 3221 ± 531 kg ha−1 and 0.68 ± 0.05 nm nm−1 (field 2 were obtained. In both fields, the yield and NDVI exhibited a strong Pearson correlation, with rxy = 0.64 and p < 10−4 in field 1 and rxy = 0.78 and p < 10−4 in field 2. The preliminary results indicate that hand-held crop sensor-based N management can be applied to wheat production in Spain and has the potential to increase agronomic N-use efficiency on a long-term basis.

  12. A Case of Hydranencephaly in Which Ophthalmic Examinations Were Performed

    Directory of Open Access Journals (Sweden)

    Shohei Eda


    Full Text Available Purpose: We performed ophthalmic examinations, including optical coherence tomography (OCT, on a case diagnosed with hydranencephaly. Case Report: This case involved a female infant born at the gestational age of 35 weeks and 4 days, with the birth weight of 2,152 g, who was one of monochorionic diamniotic twins, and the identical twin died in utero at the gestational age of 24 weeks. After that, examination by fetal echo indicated that she had microcephaly and ventriculomegaly. Postnatal magnetic resonance imaging (MRI of her head indicated microcephaly and significant enlargement of the lateral ventricle on both sides, with no obvious signs of elevated intracranial pressure. The brain parenchyma of both sides of the frontal lobe, parietal lobe, and occipital lobe had marked thinning, yet that of the temporal lobe, basal ganglia, thalamus, brain stem, and cerebellum had been maintained. Moreover, no obvious hematoma or neoplastic lesions were observed. Ophthalmic examinations indicated that both of her eyes had slight light reflex, attributed to optic nerve atrophy. Examination by use of a hand-held OCT system indicated a layered structure of the retina and thinning of the ganglion cell layer. Flicker electroretinogram (ERG examination by use of a hand-held ERG system indicated an almost normal wave. However, no clear visual reaction was observed when she was 10 months old. Conclusion: Our findings in this case of hydranencephaly revealed that even though the outer layer functions of the patient’s retina were maintained, extensive damage to her cerebral cortex resulted in poor visual function.

  13. Remote quality assurance in cervical cancer screening in low resource settings using a handheld smartphone-based colposcope (United States)

    Millien, Christophe; Jean-Baptiste, Meredith C.; Manite, Garçon; Levitz, David


    Cervical cancer is a leading cause of cancer death for women all across the developing world, where much of the infrastructure required for effective cervical cancer screening is unavailable because of limited resources. One of the most common method to screen for cervical cancer is by visual inspection with acetic acid (VIA), in which the cervix is imaged with the naked eye. Given inherent challenges in analysis and documentation when characterizing cervical tissue with the naked eye, an optical solution is needed. To address this challenge, a smartphone was modified and transformed into a mobile colposcope (a device used to image the cervix from outside) by adding a custom-fit light source and optics. The mobile smartphone colposcope was designed such that it augments VIA and easily integrates within the standard of care. The mobile smartphone colposcope is controlled by an app, which, stores cervical images captured on the mobile smartphone colposcope on a portal, enabling remote doctors to evaluate images and the treatment chosen by the health worker. Images from patients undergoing cervical cancer screening by a nurse using VIA in the University Hospital of Mirebalais (HUM) GYN outpatient clinic in Haiti were captured on the mobile smartphone colposcope. These images were later analyzed by an experienced OB/GYN at HUM, who determined whether or not the patient should be treated with cryoablation; more complicated cases were also shared with a consulting doctor in the US. The opinions of the experienced OB/GYN doctors at HUM, as well as the experts from the US, were used to educate nurses and midwives performing mobile colposcopy. These results suggest that remote assessment offered by mobile colposcopy can improve training of health workers performing VIA, and ultimately affect the therapy administered to patients.

  14. Death caused by a signal rocket--not an isolated case*. (United States)

    Alempijević, Djordje; Jecmenica, Dragan; Pavlekić, Snezana; Savić, Slobodan; Kovacević, Slobodan


    Fatalities related to sporting events are predominantly caused by blunt force injuries especially due to the emotional involvement of crowd, but occasionally other types of trauma are reported as well. A case of very rare trauma caused by shooting with a hand-held parachute signal rocket during a football match is presented. A 17-year-old football fan sustained fatal injuries, a combination of mechanical trauma caused by rocket penetration, as well as extensive thermal burning of the thoracic viscera. Analysis of the event was based on autopsy findings and evidence produced by medicolegal and ballistic experts. Improper use of a hand-held signal rocket, designed for marine distress signals, may cause serious injuries either mechanically, due to explosion, or as a result of thermal discharge. In the reported case, pattern of injuries is discussed, and medical finding corroborated to other available evidence. The presented case is a reminder that the forensic pathologist should be informed accordingly on the type and features of weapon suspected to produce injury, to be able to understand traumatic changes, and look for potential presence of foreign bodies at postmortem examination.

  15. 手持式电动工具产品日常检测不合格项目及原因浅析%Unqualified Items and Cause Analysis in Hand-held Electric Tools Routine Test

    Institute of Scientific and Technical Information of China (English)

    高家材; 陈其勇; 郑小龙


    基于日常检测尤其是CCC检测和监督抽查以及各类地方抽查的试验,介绍手持式电动工具在测试过程中常见的不合格项目,对不合格项目的产生原因进行简要分析.%Based on the routine test, especially the CCC certification, supervision and various local spot check, introduce the common unqualified items during the process in the hand-held electric tools test, and analyze the cause of the unqualified items briefly.

  16. 简介手持式电动工具爬电距离和电气间隙的测量试验%The Measuring Test of Creepage Distance and Clearance on Hand-held Electric Tools

    Institute of Scientific and Technical Information of China (English)



    基于对《手持式电动工具的安全第一部分:通用要求》具体章节的理解,通过图例方式对爬电距离和电气间隙测量的试验方法和注意事项做简单介绍。%According to the understanding of Safety of hand-held moter-operated electric tools-part 1:General requirement, to make a simple introduction of creepage distance and clearance test methods and notes by illustration.

  17. Evaluation of a hand-held far-ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens

    Directory of Open Access Journals (Sweden)

    Nerandzic Michelle M


    Full Text Available Abstract Background Environmental surfaces play an important role in transmission of healthcare-associated pathogens. There is a need for new disinfection methods that are effective against Clostridium difficile spores, but also safe and rapid. The Sterilray™ Disinfection Wand device is a hand-held room decontamination technology that utilizes far-ultraviolet radiation (185-230 nm to kill pathogens. Methods We examined the efficacy of disinfection using the Sterilray device in the laboratory, in rooms of hospitalized patients, and on surfaces outside of patient rooms (i.e. keyboards and portable medical equipment. Cultures for C. difficile, methicillin-resistant Staphylococcus aureus (MRSA, and vancomycin-resistant Enterococcus (VRE were collected from commonly-touched surfaces before and after use of the Sterilray device. Results On inoculated surfaces in the laboratory, application of the Sterilray device at a radiant dose of 100 mJ/cm2 for ~ 5 seconds consistently reduced recovery of C. difficile spores by 4.4 CFU log10, MRSA by 5.4 log10CFU and of VRE by 6.9 log10CFU. A >3 log10 reduction of MRSA and VRE was achieved in ~2 seconds at a lower radiant dose, but killing of C. difficile spores was significantly reduced. On keyboards and portable medical equipment that were inoculated with C. difficile spores, application of the Sterilray device at a radiant dose of 100���mJ/cm2 for ~ 5 seconds reduced contamination by 3.2 log10CFU. However, the presence of organic material reduced the lethal effect of the far-UV radiation. In hospital rooms that were not pre-cleaned, disinfection with the Sterilray device significantly reduced the frequency of positive C. difficile and MRSA cultures (P =0.007. Conclusions The Sterilray™ Disinfection Wand is a novel environmental disinfection technology that rapidly kills C. difficile spores and other healthcare-associated pathogens on surfaces. However, the presence of organic matter

  18. 基于手持设备的室内定位系统设计与实现%Design and implement an indoor location system based on handheld device

    Institute of Scientific and Technical Information of China (English)

    胡天琨; 叶建芳


    Designing an indoor location system based on handheld device to resolve the matter that cannot use GPS for indoor location. This system has two feature, the first is combining the inertial positioning and WiFi positioning; the second is the system is very simple, just need a handheld device that include WiFi, compass, inertial sensor. Present a path matching algorithm used in inertial positioning and site estimated algorithm used in WiFi positioning. It has been found that the precision of system is less than 4 m.%为解决无法在室内使用GPS的问题,设计并实现了基于常用手持设备(如手机、平板电脑)的室内定位系统。系统融合了传统的惯性定位方法和基于WiFi信号强度定位方法,易于搭建,仅需一个包含惯性传感器、电子罗盘、WiFi扫描的手持设备。提出了惯性定位中的路径匹配算法和WiFi信号定位方法中的位置估计算法。经实际测试,系统定位精度小于4m。

  19. GPS RTK and Handheld GPS in the Measurement of Land Consolidation in Combination%GPS RTK与手持GPS在土地整理核查测量中的联合应用

    Institute of Scientific and Technical Information of China (English)



    RTK with its positioning speed,high positioning accuracy is widely used in measurement.Handheld GPS with its small volume,convenient carrying,its accuracy can reach a certain requirement.According to low precision,RTK combined with handheld GPS will play a technological advantage greatly,and improves the labor rate.The combined ap-plication of both is explored.%RTK以其定位快,定位精度高的特点广泛的应用于测量之中。手持 GPS因其体积小,携带方便,精度也能达到一定的要求,针对于一般精度要求较低的测量工作来说, RTK与手持GPS联合应用必将发挥极大的技术优势,并大大提高劳动率。本文针对于两者的联合应用进行探讨。

  20. Design and experiment on handheld air-assisted pollination device%手持式风送授粉机研制与试验

    Institute of Scientific and Technical Information of China (English)

    丁素明; 薛新宇; 蔡晨; 秦维彩; 方金豹; 孙竹


    Pollination is a very important process for high yield and quality of fruits production. The artificial and bee pollinations are wildly used in fruits production, but they are unadaptable to large scale production. So a kind of handheld air-assisted pollination device was developed. Through theoretical calculation, the air supply device was determined to adopt 6 impellers, the impeller diameter is 38 mm and the guide blades width is 18 mm. The motor is driven by DC power. A wind velocity indicator was used and the test ring was put at 500 mm ahead of the air inlet which is connected with a set of rams to fan pipes. The ram’s diameter is 38 mm, same as the impeller. The results of fan performance test showed that the air volume was 3.0×10-3m3/s at 8 000 r/min of fan speed, which can meet the design requirements. The highest total pressure efficiency is 43% at 9 000 r/min of fan speed. With the speed increase, the total pressure efficiency dropped rapidly but the power increased and the variation trends of the air volume and air pressure are not significant. The fan property was tested and the performance curve graphic was drawn. The air velocity field at different rotational speeds of the handheld air-assisted pollination device were studied and validated by the experiment data. The results showed that the velocity of central plane diffused at a fixed angle and decayed along the centre line, and the theoratical values closely related to the experiment data. In order to study the effect of airflow speed on pollination, the basic principle of pneumatic pollination was analyzed. Tests were conducted to validate the effect of airflow speed on pollens distribution based on pollens density, horizontal distribution and vertical distribution in the lab. The results show that the flow rate of nozzle is affected by wind velocity significantly. When the winds velocity reaches 25 m/s, the variation trends of the flow rate of nozzle are not significant with the speed increase

  1. Distance Estimation Using Handheld Devices (United States)


    to 6 mm) and a fixed aperture (around f/2.8) [14]. The cutting edge technology in mobile camera sensors is currently provided by Nokia with The Nokia 808 PureView’s camera offers a set of leading specifications, such as 8mm focal length, 41 Mb resolutions and an aperture of from focus for cell-phone Cameras, San Jose, 2008. [15] Nokia , Detailed specifications for the Nokia 808 PureView. [Online]. Available:http

  2. Accentuated Factors of Handheld Computing

    DEFF Research Database (Denmark)

    Andersson, Bo; Henningsson, Stefan


    The recent years of rapid development of mobile technologies create opportunities for new user groups in the mobile workforce to take advantage of information systems (IS). However, to apprehend and harness these opportunities for mobile IS, it is crucial to fully understand the user group...... and the mobile technology. In this chapter, we deductively, from previous research on aspects on mobility, synthesize a tentative analytical framework capturing factors accentuated in mobile IS design. We evaluate the framework based on criteria of completeness, distinctiveness and simplicity. Eventually...

  3. Accentuated Factors of Handheld Computing

    DEFF Research Database (Denmark)

    Andersson, Bo; Henningsson, Stefan

    The recent years of rapid development of mobile technologies creates opportunities for new user-groups in the mobile workforce to take advantage of in-formation systems (IS). However, to apprehend and harness these opportunities for mobile IS it is crucial to fully understand the user group...... and the mobile tech-nology. In this paper we deductively, from previous research on aspects on mobili-ty, synthesize a tentative analytical framework capturing factors accentuated in mobile IS design. We evaluate the framework based on criteria of completeness, distinctiveness, and simplicity. Eventually...

  4. Hand-Held UXO Discriminator (United States)


    studies also included various capacitors , resistors, damping factors and coupling in both the S and T-termination modes. The accuracy of the used as follows: (1) teflon, (2) polypropylene , (3) polystyrene, (4) polyethylene (foam is better than solid). 2.4 Fabrication and assembly...shields several different ways as well. These included floating ground, grounded to the data acquisition board, grounded to 24 V capacitor , with

  5. Hand-held survey probe (United States)

    Young, Kevin L [Idaho Falls, ID; Hungate, Kevin E [Idaho Falls, ID


    A system for providing operational feedback to a user of a detection probe may include an optical sensor to generate data corresponding to a position of the detection probe with respect to a surface; a microprocessor to receive the data; a software medium having code to process the data with the microprocessor and pre-programmed parameters, and making a comparison of the data to the parameters; and an indicator device to indicate results of the comparison. A method of providing operational feedback to a user of a detection probe may include generating output data with an optical sensor corresponding to the relative position with respect to a surface; processing the output data, including comparing the output data to pre-programmed parameters; and indicating results of the comparison.

  6. The designing of Hand-held boiler with the monitor%手持式电站锅炉配风监测仪的设计

    Institute of Scientific and Technical Information of China (English)

    刘勇; 朱杰斌


    In view of the current boiler burner field patrol, maintenance equipment, developed a crushing handheld boiler with the wind, it is imperative to monitor. Based on the understanding of pulverized coal boiler with the working principle of the monitoring system,and based on the principle of measurement, the calibration of the first ever speed, the measuring element differential transmission device to measure the internal pressure sensor measuring pressure; send out variable Secondly anemometer can be calculated by wind, By three again for measuring temperature and air temperature, coal powder mixture platinic resistance sensor, the temperature of the measured value and calculated according to the principle of thermal pulverized coal concentration. Mainly introduces the basic circuit design hardware structure and low power circuit design, the key is presented, the main program software flowchart monitoring and presented with FengYi boiler pressure measurement results and meet the design requirements. The experiment proves, plant technical personnel, use convenient,reliable operation cost is low, have a high application value.%针对当前电站锅炉燃烧器的现场巡视、检修设备的溃乏,研制一种手持式电站锅炉配风监测仪势在必行.基于在了解电站锅炉煤粉配风监测系统的工作原理以及测量工作原理的基础上,首先采用经标定过的测速元件测量,经差压变速器送到测量装置内部的压力传感器变送测量出动压;其次由测速原理可以计算出风速;再次由三支分别用于测量热风温度、煤粉温度和风粉混合温度的铂电阻传感器所测得的温度值,根据热平衡原理计算出煤粉浓度.重点介绍了基本设计电路硬件结构以及关键低功耗电路设计,既给出了监测仪主程序软件流程图,又给出了电站锅炉配风仪动压测量的结果分析,达到了设计的要求.经电厂技术人员试验证明,运行可靠,使用方便,成本低,有较高的推广价值.

  7. 手持式电动工具防止触及带电零件的保护试验%Protection against Access to Live Parts Test of Hand-held Electric Tools

    Institute of Scientific and Technical Information of China (English)



    According to the understanding of the standard of protection against access to live parts test of hand-held electric tools, brief introduce the test methods and results determination by legends, including the test equipments, test methods, results determination and precautions.%根据对手持式电动工具防止触及带电零件试验的标准理解,通过图例对该试验方法和结果判定作简单介绍,包括试验设备、试验方法、结果判定以及注意事项等方面。

  8. 手持式电动工具用轴承性能浅析%Brief Performance Analysis on the Bearings Applied to Hand-held Motor-operated Electric Tools

    Institute of Scientific and Technical Information of China (English)

    张永恩; 方承志; 宋贵州; 李兴林


    Deep groove ball bearings, represented in the tool assembly without considering other factors, combined with the relevant sections of the power tool safety standards, the content mainly discusses several performance requirements of the bearings applied to hand-held motor-operated electric tools and their relationship and effects with safety standard. This content can also be referenced while make technical design and quality appraisal.%以深沟球轴承为代表,在不考虑工具装配等因素的前提下,结合电动工具安全标准的相关章节,讨论并分析手持式电动工具用滚动轴承的主要性能和要求,可供设计选用和质量评价时参考。

  9. 基于用户需求的家用电动工具造型设计研究%Research on Household Hand-held Electric Tools Sculpting Design Based on User Demand

    Institute of Scientific and Technical Information of China (English)



    基于产品造型设计相关理论,在功能、美学和经济性要求的基础上,分析探讨多学科优化设计原理、系列化设计原理、产品基因原理与协同设计等原则应用于家庭用手持式电动工具系列产品,并进行实例设计.%Based on the related theory of sculpting design and on the basis of function, aesthetic and economic requirements, analyze and discuss the multidisciplinary optimization design principle, series design principle, product gene principle and collaborative design principle, applying to household hand-held power tool series products and instantiate the design.

  10. To Construct a Three-dimensional Cradle Model Based on the Handheld Laser Scanning Technology%基于手持式激光扫描技术构建三维支座模型

    Institute of Scientific and Technical Information of China (English)



    本文通过分析手持式激光三维激光扫描系统的技术、方法和流程,介绍了如何结合VxScan、Geomag ic Studio和UG软件进行点云数据处理、三角面片修饰,进而构建完整的三维表面模型的方法,利用该方法可以快速的对物品进行三维可视化建模。%This paper analyzes the handheld laser 3D laser scanning system techniques, methods and processes, describes how to combine VxScan, Geomag ic Studio and UG software for point cloud data processing, modification of triangular facets, and then builds a complete three-dimensional surface methods model, using this method can quickly item visualization modeling.

  11. 手持心率变异性采集分析系统的设计%Design of Hand-held Heart Rate Variability Acquisition and Analysis System

    Institute of Scientific and Technical Information of China (English)

    李开元; 王步青; 王卫东


    提出了手持式心率变异性采集、分析系统的设计,通过双手按触电极采集并存储患者的5分钟心电信号;利用USB口上传PC机,使用LabVIEW编写的软件分析心率变异性参数;心率变异性参数计算,计算函数用matlab编写并生成com组件实现.%A design of handheld heart rate variability acquisition and analysis system is proposed. The system collects and stores the patient's ECG every five minutes through both hands touching on the electrodes, and then -uploads data to a PC through USB port. The system uses software written in LabVIEW to analyze heart rate variability parameters, The parameters calculated function is programmed and generated to com components in Matlab.

  12. Three Case Reports of Successful Vibration Therapy of the Plantar Fascia for Spasticity Due to Cerebral Palsy-Like Syndrome, Fetal-Type Minamata Disease. (United States)

    Usuki, Fusako; Tohyama, Satsuki


    Fetal-type Minamata disease is caused by the exposure to high concentrations of methylmercury in the fetal period and shows cerebral palsy-like clinical features. Relief of spasticity is a major task of rehabilitation to improve their activities of daily living. Here we report the effect of long-term vibration therapy on bilateral lower-limb spasticity in 3 patients with fetal-type Minamata disease. We used a simple, inexpensive, and noninvasive approach with hand-held vibration massagers, which were applied to the plantar fascia at 90 Hz for 15 minutes. The effect was observed soon after the first treatment and resulted in better performance of the repetitive facilitation. Vibration therapy for 1 year improved Modified Ashworth Scale for the ankle flexors in 2 cases. The labored gait improved and gait speed increased in another case. Continued vibration therapy for another 1 year further improved Modified Ashworth Scale score and range of motion of ankle dorsiflexion in 1 case. This case showed the decreased amplitude of soleus H-reflex after the 15-minute vibration therapy, suggesting that α-motor neuron excitability was suppressed. Vibration therapy using a hand-held vibration massager may offer safe and effective treatment for lower-limb spasticity in patients with chronic neurological disorders.

  13. Desenvolvimento de software oftalmológico para computação móvel Development of ophthalmologic software for handheld devices

    Directory of Open Access Journals (Sweden)

    Gustavo Teixeira Grottone


    do grupo Ultrascan foi de 20,93D. Resultado semelhante à média do grupo programa em estudo. Os desvios-padrão das amostras também foram semelhantes (4,53D. CONCLUSÃO: A precisão do programa testado foi semelhante a do aparelho de ultra-sonografia ocular Ultrascan, para a fórmula SRK/T. O funcionamento do programa se demonstrou estável sem travamentos nos testes efetuados. A utilização deste programa em unidades cirúrgicas onde exista a necessidade de troca ou recálculo da lente intra-ocular do paciente, é alternativa segura, móvel e portátil, que pode auxiliar o cirurgião na escolha de uma nova lente.INTRODUCTION: The formulas for calculation of intraocular lenses have evolved since the first theoretical formulas by Fyodorov. Among the second generation formulas, the SRK-I formula has a simple calculation, taking into account a calculation that only involved anteroposterior length, IOL constant and average keratometry. With the evolution of those formulas, complexicity increased making the reconfiguration of parameters in special situations impracticable. In this way the production and development of software for such a purpose, can help surgeons to recalculate those values if needed. PURPOSE: To idealize, develop and test a Brazilian software for calculation of IOL dioptric power for handheld computers. METHODS: For the development and programming of software for calculation of IOL, we used PocketC program (OrbWorks Concentrated Software, USA. We compared the results collected from a gold-standard device (Ultrascan/Alcon Labs with the simulation of 100 fictitious patients, using the same IOL parameters. The results were grouped for ULTRASCAN data and SOFTWARE data. Using SRK/T formula the range of those parameters included a keratometry varying between 35 and 55D, axial length between 20 and 28 mm, IOL constants of 118.7, 118.3 and 115.8. RESULTS: Using Wilcoxon test, it was shown that the groups do not differ (p=0.314. We had a variation in the

  14. 手持式压力测痛仪的信度及效度检验%Reliability and validity of the hand-held pressure algometer as a measuring instrument of pressure pain threshold

    Institute of Scientific and Technical Information of China (English)

    陈祢; 郭铁成; 许惊飞; 韦春霞


    目的 均较高(ICC>0.95),重测信度优于施测者间信度;根据同一施测者3次重复测量结果的均值所计算的施测者间信度高于单次测量的施测者间信度;肌筋膜痛患者激痛点与正常对照点的压痛阈差异具有统计学意义,激痛点压痛阈值与VAS评分呈显著的负相关.结论 手持式压力测痛仪测量正常健康人压痛阈时具有较高信度,其可作为量化评价激痛点疼痛敏感性的有效工具.%Objective To evaluate the test-retest and inter-rater reliability of the hand-held pressure algometer as a measuring instrument of pressure pain threshold(PPT).Method A total of 37 healthy subjects were recruited for reliability test.Three raters measured the PPT at 12 body sites of the subjects.Each rater conducted three trials on each site.In the validity test,10 patients with active trigger points in the upper trapezius were recruited and measured by one rater using the pressure algometer for PPT,the visual analogue scale(VAS)was also used to evaluate the pain intensity induced by the trigger point.The intraclass correlation coefficient and Spearman correlation coefficient were calculated to reflect the reliability and validity.Results The test-retest and inter-rater reliabilities were both high(ICC>0.95),with the measurements by one rater were more reliable than measurements by multiple raters.The inter-rater reliability of PPT measurement obtained by using the mean value of 3 trials was higher than any of the 3 trials alone.The PPT values of the trigger points were higher than those of the normal points,and there was a significantly negative correlation between the PPT values of the trigger points and the VAS scores.Conclusion The intra-and inter-rater PPT measurements in healthy subjects obtained with the hand-held pressure algometer were highly reliable.The algometer was valid for quantifying myofascial trigger point sensitivity.

  15. 手持式电动工具维修风险和零件选配技术研究%Research on Repair Risk and Component Matching Technology of Hand-held Electric Tools

    Institute of Scientific and Technical Information of China (English)

    金勇; 傅俊雅


    模拟手持式电动工具维修情况,对手持式电动工具的电源线、开关、碳刷以及抑制电容电感等关键零部件进行更换试验,按照相关的国家标准要求分别对替换后的安全、电磁兼容等项目进行测试和数据比对。分析常见的手持式电动工具关键零部件被替换为非原厂零件的特征。%We simulate key parts changing in maintenance and repair when using non original parts, mainly power supply cord, switch, brush and capacitor and inductance, doing lots of tests and data comparison according to the national standards of safety and electromagnetic compatible. We f ind out common characteristics that key parts are replaced by non-original parts in hand-held electric tools.

  16. 手持式三维激光扫描仪定位算法的研究%Research on the Positioning Algorithms of a Handheld 3d Scanner

    Institute of Scientific and Technical Information of China (English)

    秦绪红; 赵杰; 程俊廷


    Self-referencing algorithms of the handheld 3 d scanner was mainly dissussed.Finst the classical algorithms is introduced,including the iterative closest point (ICP) algorithm and the exhaustive distance algorithm,and it also introduces the defects that exist in these algorithms.Then three triangulation algorithms are introduced.Throagh experiment,the three triangulation algorithms is compared with the reference exhaustive-distance algorithm,and analysied the advantages and disadvantages of these algorithms.The resalts are used to determine the best of the three.%研究了手持式三维扫描仪的自定位算法,并提出了改进算法以弥补ICP算法和穷举法等经典定位算法的局限性.通过实验对比Delaunay四面体法、ICP算法、最小三角形法和频率三角形法的重构效率,实验结果表明频率三角形法更高效更稳定,在各种环境下均具有可行性.

  17. 基于手持式设备的高校教师培训策略研究%Research on the College Teachers’ Training Strategy Based on the Handheld Device

    Institute of Scientific and Technical Information of China (English)

    郭腾; 刘东兴; 刘淑梅


    With the rapid development and integration of computer network technology and mobile communications technol-ogy, and the rapid spread of mobile terminal, research and application of the mobile learning developed rapidly. Mobile learn-ing model is applied to the college teachers’ training. It becomes possible for the teachers to learn anytime, anywhere with the handheld device. It solved the problem of heavy tasks and lack of time. The efficiency of teachers’ training was significantly increased.%  随着计算机网络技术和移动通信技术的迅速发展,以及移动终端设备的快速普及,移动学习的研究和应用迅速兴起。移动学习模式应用于高校教师培训中,参训教师利用手持式设备在任何时间任何地点开展学习成为可能,且有利于知识的学以致用,解决了教师工作任务重、时间紧的难题,培训效率显著提高。

  18. 手持无线视频监控系统的设计与实现%Design and Implementation of Wireless Video-monitoring System Based on Handheld Devices

    Institute of Scientific and Technical Information of China (English)

    李裕; 张玲华


    随着无线通信的快速发展、无线传输带宽的增大,尤其是3G网络的使用,无线手持移动终端的DSP处理能力不断增强,无线移动终端已可以成为视频采集系统的终端.Windows Mobile是目前移动设备中较为流行的智能终端操作系统.对如何构建远程无线视频采集(监控)系统的关键技术进行深入的研究.并在Windows Mobile平台上实现了该系统.%With the rapid development of wireless communications, the increasing of wireless transmission bandwidth, especially the using of 3G network, and the wireless handheld mobile device's capacity of DSP processing enhancing, wireless mobile terminals already becomes a terminal of wireless video surveillanee system. Windows Mobile is a popular mobile device operating system at present. How to construct a remote wireless video collection (surveillance) system is researched, and the system is realized on Windows Mobile platform.

  19. Nondestructive Handheld Fourier Transform Infrared (FT-IR) Analysis of Spectroscopic Changes and Multivariate Modeling of Thermally Degraded Plain Portland Cement Concrete and its Slag and Fly Ash-Based Analogs. (United States)

    Leung Tang, Pik; Alqassim, Mohammad; Nic Daéid, Niamh; Berlouis, Leonard; Seelenbinder, John


    Concrete is by far the world's most common construction material. Modern concrete is a mixture of industrial pozzolanic cement formulations and aggregate fillers. The former acts as the glue or binder in the final inorganic composite; however, when exposed to a fire the degree of concrete damage is often difficult to evaluate nondestructively. Fourier transform infrared (FT-IR) spectroscopy through techniques such as transmission, attenuated total reflectance, and diffuse reflectance have been rarely used to evaluate thermally damaged concrete. In this paper, we report on a study assessing the thermal damage of concrete via the use of a nondestructive handheld FT-IR with a diffuse reflectance sample interface. In situ measurements can be made on actual damaged areas, without the need for sample preparation. Separate multivariate models were developed to determine the equivalent maximal temperature endured for three common industrial concrete formulations. The concrete mixtures were successfully modeled displaying high predictive power as well as good specificity. This has potential uses in forensic investigation and remediation services particularly for fires in buildings.

  20. The Utilization of Wireless Handheld Computers with MEDLINE is an Effective Mechanism for Answering Clinical Questions at the Point of Care. A Review of: Hauser, Susan E., Dina Demner-Fushman, Joshua L. Jacobs, Susanne M. Humphrey, Glenn Ford, and George R. Thoma. “Using Wireless Handheld Computers to Seek Information at the Point of Care: An Evaluation by Clinicians.” Journal of the American Medical Informatics Association 14.6 (Nov./Dec. 2007: 807-15.

    Directory of Open Access Journals (Sweden)

    Martha Ingrid Preddie


    Full Text Available Objective – To assess the effectiveness of wireless handheld computers (HHCs for information retrieval in clinical environments and the role of MEDLINE in answering clinical questions at the point of care. Design – A prospective single-cohort study.Setting – Teaching rounds in the intensive care units and general medicine wards in two hospitals associated with a university’s school of medicine in the United States. Subjects – Five internal medicine residents with training in evidence-based practice.Methods – While accompanying medical teams on teaching rounds for approximately four consecutive weeks, each resident used MD on Tap (an application for handheld computers on a TreoTM 650 PDA/cell phone to find answers in real time, to questions that were raised by members of the medical teams. Using a special version of MD on Tap, each resident initialized a UserID. Serving as evaluators, the residents described and categorized clinical scenarios and recognized questions. They also formulated search terms, searched MEDLINE and identified citations determined to be useful for answering the questions. An intermediate server collected details of all MEDLINE search query transactions, including system response time, the user (based on UserIDs, citations selected for viewing, the saving of citations to HHC memory, as well as use of the Linkout and Notes features. In addition evaluators submitted daily summaries. These summaries included information on the scenarios, clinical questions, evidence-based methodology (EBM category, the team member who was the source of the question, the PubMed Identifiers (PMIDs of relevant citations, and comments. At the end of the data collection period, each evaluator submitted a summary report consisting of a qualitative and quantitative evaluation of his experience using MEDLINE via the handheld device to find relevant evidence based information at the point of care. The report also focused on the usefulness

  1. Assurance Cases (United States)


    2015 Carnegie Mellon University Assurance Cases Software Engineering Institute Carnegie Mellon University Pittsburgh, PA 15213 Charles B...1. REPORT DATE 26 JAN 2015 2. REPORT TYPE N/A 3. DATES COVERED 4. TITLE AND SUBTITLE Assurance Cases 5a. CONTRACT NUMBER 5b. GRANT NUMBER... Assurance Cases Charles B. Weinstock, January 2015 © 2015 Carnegie Mellon University Copyright 2015 Carnegie Mellon University This material is based upon

  2. Handheld devices control the variable LED information board remotely with wireless signal%手持设备无线遥控LED可变信息情报板探讨

    Institute of Scientific and Technical Information of China (English)

    龚欢; 赵蕊; 杨东雷; 周跃华


    探讨手持设备无线遥控LED可变信息情报板技术,通过使用手机上的蓝牙模块发布、控制工程车后部的LED诱导屏信息变化,采用Java编写应用程序输入手机系统,探讨方案实施的可行性。该远程无线通信遥控方法亦可解决城市公路诱导屏、情报板等控制光缆损坏情况下临时发布信号,信号准确、低功耗、无流量费用,且该技术可设置加密匹配,防止盗用。该方法控制方便,构思新颖,可靠准确,绿色节能,安全可靠。%It’ s the article of exploring the handheld device controlling the variable LED information board remotely with wireless signal. This technology display the information on the upper control truck high-end LED screen change through the use of mobile phones with Bluetooth module,. The controlling application is written by Java which runs on Android system to provide the feasibility of the scheme. This technology can also solve the problem for urban highway guidance screen when its cable is damaged The signal need no flow cost with less mistakes and it’s low power consumption. As well, it needs to be authenticated for pro-tecting used by others. This method is easy to control. The design is novel, reliable, accurate, green, energy saving and security.

  3. 基于iOS手持终端的移动学习资源设计研究%Research on M-learning Resource Design Based on iOS Handheld Device

    Institute of Scientific and Technical Information of China (English)

    李蕾; 李晓丽


    移动互联网时代,移动手持设备普及已经相当广泛,设计适合移动学习的资源已经成为移动学习研究的关键问题。该文基于非正式学习与微型学习理论,根据成人移动学习者的特征提出了移动学习资源设计的原则与流程,在此基础上、充分利用iOS的个性化特性设计开发了基于iOS的“地震知识轻松学”移动学习软件,重点介绍了版式与内容分离技术和个性化手势技术的实现。%In Mobile Internet Times, Mobile handheld devices have been widely spread, Design of mobile learning resources have already become the key problem of mobile learning research. In this paper, based on the theory of informal learning and micro learning, according to the characteristics of adult mobile learners, mobile learning resource design principles and process is proposed, and developed a mobile learning software called“earthquake knowledge easy learning”based on the personalized characteristics of iOS technology, Mainly introduces the layout and content separation technology and personalized gesture technology.

  4. Mobile Software Testing – Automated Test Case Design Strategies

    Directory of Open Access Journals (Sweden)

    Selvam R,


    Full Text Available Mobile devices are poised to challenge PCs as the application platform of choice, with 500 million mobile internet devices expected to ship in 2012 compared to 150 million PCs. The convergence ofall digital devices into mobile platform model augments the software companies, software developer, and venture capitalist firms to turn their focus into mobile application platform (for example mobile social networking application like face book and mobile VOIP like Skype a futuristic platform for increased revenue, new challenges and growth potential. But the commercial success of these applications depends on their working smoothly and securely on a wide variety of handheld devices and wireless networks. More and more virtual mobile application stores are built on the web. The web itself is in the transforming form to adapt to the mobile devices to thrive on. The sudden growth in the mobile application and the complexity in the divergence of the devices that uses these applications present increased challenges and opportunities for the software testing companies and software testers to conquerthis small device. Performing such testing quickly and cost-effectively greatly expands the market for such applications. This paper deals the nuances of Automated Test Case Design Strategies for Mobile Software Testing.

  5. Case - Case-Law - Law

    DEFF Research Database (Denmark)

    Sadl, Urska


    Reasoning of the Court of Justice of the European Union – Constr uction of arguments in the case-law of the Court – Citation technique – The use of formulas to transform case-law into ‘law’ – ‘Formulaic style’ – European citizenship as a fundamental status – Ruiz Zambrano – Reasoning from...

  6. Design of Hand-held Picking Device for Brasenia Schreber Aquatic Plant%水生莼菜植物手动控制采摘器的设计

    Institute of Scientific and Technical Information of China (English)

    夏春风; 马燕平; 沈长生; 张宇


    针对水生莼菜植物手工采摘辛苦、效率低下等问题,设计了一种手动控制的莼菜采摘器,分析了其工作原理,给出莼菜切割力计算公式。该采摘器由人手驱动,通过向后逐渐收紧手柄,使与手柄相连的钢丝后移,后移的钢丝再带动直槽形钢片、刀片支架等运动,使主、副刀片闭合,完成莼菜切割运动。然后,操作者将采摘装置移出水面,将切割好的莼菜移到收集装置的网兜上方,松开手柄,主、副刀片自动松开,使莼菜自然落入网兜中。实验表明,该采摘器能达到设计要求,且可靠性高、使用方便、控制灵活,对莼菜和水体均不造成污染。%Am at to solve the problem that brasenia schreberi aquatic plant picked hard and low efficiency by hand , a hand-held picking device for brasenia schreber was designed .Its working principle was introduced , and the calculation formula of brasenia schreberi cutting force was presented .The picking device was driven by hand and by tightening the handle backwards , so that the steel wire connected to the handle moved backward ,the back steel wire drove the piece of straight-shaped steel and the blade holder , closed the main and auxiliary blade and completed cutting brasenia schreberi .Then , the picking device was moved out of the water by the operator , the cut brasenia schreberi was moved to the above net of collecting device ,fell into the net naturally by loosening the handle and releasing the main and auxiliary blade automatically .The picking device of design and manufacture can meet the design requirements through practice test and does not pollute the water and brasenia schreberi .The picking device has the advantages of high reliability , conven-ient to use ,flexible control .

  7. Dermatology case

    Directory of Open Access Journals (Sweden)

    Sandrina Carvalho


    Full Text Available Pilomatrixoma is a benign tumor of skin appendages with follicular differentiation most frequently found in children and adolescents, predominantly female. Clinically it is characterized by an erythematous-violaceous mobile nodule of hard consistency located on the head or neck. Although rare, multiple pilomatrixomas can be associated with other pathologies, particularly myotonic dystrophy or Steinert’s disease. In these cases, a prolonged follow-up should be maintained to rule out relapses and/or development of other diseases. We describe the case of a 9-year-old girl with multiple pilomatrixomas.

  8. Case work

    DEFF Research Database (Denmark)

    Shaw, Ian Frank


    Answers to the question just what is the ?case? partly defined the fields of sociology and social work in early 20th century Chicago. Drawing on the archives of the University of Chicago, I describe and appraise the way the ?case? figured in social work at Chicago and elsewhere. I ask...... the corresponding question of sociology. Finally, I briefly consider why not much came of social work and sociology ploughing similar territory in ways that served for a time to hallmark their identities. This analysis opens up ways of rethinking how social work and sociological research are distinctive...

  9. Forest stand spatial structure measurement method using handheld tree measurement smart station%利用手持式超站测树仪测量林分空间结构参数

    Institute of Scientific and Technical Information of China (English)

    冯仲科; 徐伟恒; 杨立岩


    Spatial structure is an important characteristic of forest and spatial distribution pattern is one part of researches on population spatial behavior.Based on the relationship of neighborhood trees, three kinds of stand spatial structure parameters including uniform angle index,mingling and dominance was proposed by Professor Gangying Hui. In the past decade, stand spatial structure parameters are widely used to analyze stand spatial structure, calculate trees dominance, judge competition among trees, measure species diversity and recover or reconstruct stand structure at domestic and international study.. Measurement accuracy of spatial structural parameters (uniform angle index, mingling degree, and dominance) has a significant role in studying stand spatial structure. In the traditional direct interpretation method(DIM), it is difficult to measure the angle between reference tree and 4 nearest neighbor trees. For this method, the error derived from tree diameters at breast height is not considered in the process of measurement, so uniform angle index value is inaccurate. Moreover, based on DIM, other two parameters of mingle degree and dominance measurement required at least two operators, one person completed measurement and the other recorded field data, thus it is impossible to calculate the observing results immediately In this paper, a new measuring method named as HSSM was proposed using handheld smart station to measure stand spatial structure parameters in order to enhance measurement precision and accuracy, decrease field investigation workload. For measuring uniform angle index , the angle between reference tree and four nearest neighbor trees is not measured directly. Firstly, X-Y coordinates of reference tree and four nearest neighbor trees are measured using handheld smart station. Secondly, the diameters at breast height of five trees are measured corresponding with each tree, specifically, diameters at breast height measurement is to obtain center

  10. Case competitions

    DEFF Research Database (Denmark)

    Schjoldager, Anne Gram


    The paper presents and discusses a teaching project with case competitions for MA students of specialised translation at the Aarhus School of Business, Aarhus University. Drawing on a series of online questionnaires, the paper ascertains how the project was evaluated by the participating students...

  11. Case report

    DEFF Research Database (Denmark)

    Füchtbauer, Laila; Brusgaard, Klaus; Ledaal, Pål;


    ey Clinical Message Vitamin D-dependent rickets type 1 VDDR-1 is a recessive inherited disorder with impaired activation of vitamin D, caused by mutations in CYP27B1. We present long-time follow-up of a case with a novel mutation including high-resolution peripheral quantitative computed tomography...

  12. Some fundamentals of handheld snow surface thermography

    Directory of Open Access Journals (Sweden)

    C. Shea


    Full Text Available This paper presents the concepts needed to perform snow surface thermography with a modern thermal imager. Snow-specific issues in the 7.5 to 13 μm spectrum such as ice emissivity, photographic angle, operator heating, and others receive detailed review and discussion. To illustrate the usefulness of this measurement technique, various applications are presented. These include detecting spatial temperature variation on snow pit walls and measuring the dependence of heat conduction on grain type.

  13. Handheld Microneedle-Based Electrolyte Sensing Platform.

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Philip R. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Rivas, Rhiana [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Johnson, David [Aquila Technologies Group, Inc., Albuquerque, NM (United States); Edwards, Thayne L. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Koskelo, Markku [Aquila Technologies Group, Inc., Albuquerque, NM (United States); Shawa, Luay [Aquila Technologies Group, Inc., Albuquerque, NM (United States); Brener, Igal [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Chavez, Victor H. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Polsky, Ronen [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)


    Sandia National Laboratories will provide technical assistance, within time and budget, to Requester on testing and analyzing a microneedle-based electrolyte sensing platform. Hollow microneedles will be fabricated at Sandia and integrated with a fluidic chip using plastic laminate prototyping technology available at Sandia. In connection with commercial ion selective electrodes the sensing platform will be tested for detection of electrolytes (sodium and/or potassium) within physiological relevant concent ration ranges.

  14. Handheld Synthetic Array Final Report, Part A (United States)


    constraints expressed as smart phone trajectory of camera features of opportunity anchor marker camera field of view R – rotation between world...Matlab program is listed at the end of the chapter. Initially the IQ data is read into the matlab workspace and combined into a set of complex samples

  15. Some fundamentals of handheld snow surface thermography

    Directory of Open Access Journals (Sweden)

    C. Shea


    Full Text Available This paper presents the concepts needed to perform snow surface thermography with a modern thermal imager. Snow-specific issues in the 7.5 to 13 μm spectrum such as ice emissivity, photographic angle, operator heating, and others receive detailed review and discussion. To illustrate the usefulness of this measurement technique, various applications are presented. These include detecting spatial temperature variation on snow pit walls and measuring the dependence of heat conduction on grain type.

  16. Handheld Synthetic Array Final Report, Part B (United States)


    environments. To this end, indoor localization systems rely on other technologies such as UWB, RFID , Bluetooth (IEEE 802.15), ultrasonic badges, and...University of Calgary 2500 University Dr, N.W. Calgary, T2N 1N4 Contract reference number: W7714-115195/A Contract Scientific Authority: Brad...Bound PF Particle Filter PRN Pseudo-Random Noise 5/154 POA Phase of Arrival RB Rao-Blackwellized RBPF Rao-Blackwellized Particle Filter RFID Radio

  17. Studying Reliability Using Identical Handheld Lactate Analyzers (United States)

    Stewart, Mark T.; Stavrianeas, Stasinos


    Accusport analyzers were used to generate lactate performance curves in an investigative laboratory activity emphasizing the importance of reliable instrumentation. Both the calibration and testing phases of the exercise provided students with a hands-on opportunity to use laboratory-grade instrumentation while allowing for meaningful connections…

  18. Hand-held microwave search detector (United States)

    Daniels, David J.; Philippakis, Mike


    This paper describes the further development of a patented, novel, low cost, microwave search detector using noise radar technology operating in the 27-40GHz range of frequencies, initially reported in SPIE 2004. Initial experiments have shown that plastic explosives, ceramics and plastic material hidden on the body can be detected with the system. This paper considers the basic physics of the technique and reports on the development of a initial prototype system for hand search of suspects and addresses the work carried out on optimisation of PD and FAR. The radar uses a novel lens system and the design and modelling of this for optimum depth of field of focus will be reported.

  19. Hand-held operational demining system



    The article presents selected results from theoretical and experimental investigations concerned with radar backscattering from typical antipersonnel land mines (APL) in the frequency range of about 200 MHz to 8 GHz in order to improve the conventional metal detector demining technology presently still widely in use.

  20. A Case for Case Report

    Directory of Open Access Journals (Sweden)

    Vivek Gharpure


    Full Text Available Evidence based medicine (EBM is becoming popular among clinicians and medical publishers; as clinical research is tested against the touchstone of EBM. Theory of Quality of Evidence, considers randomized controlled trials to be the best quality evidence, while case reports and expert opinions are considered at the lowest ebb

  1. Corruption case. (United States)


    A Federal jury in Puerto Rico found three defendants guilty of participating in the theft of $2.2 million in Federal funds from the San Juan AIDS Institute. The key figure in the case is [name removed], a consultant to the institute. He was convicted of 12 counts of money laundering and faces up to 25 years in prison. Two other administrative officials were also convicted in the case. Four others have pleaded guilty, and three more await trial. Rep. Jose Granados Navado was among those implicated; he received $100,000 for his campaign for mayor of San Juan in 1988 from the institute=s medical director. U.S. Rep. Tom Coburn (R-Okla.) has called for an audit of all Ryan White CARE Act funds since this scandal was uncovered.

  2. Dermatology case

    Directory of Open Access Journals (Sweden)

    Catarina Dias


    Full Text Available Glomuvenous malformations, also known as glomangiomas, are tumor-like malformations or hamartomas of the glomus body. They can be sporadic or inherited as an autosomal dominant disease. Glomuvenous malformations tend to resemble hemangiomas. Clinical distinction between these entities is important due to their different therapeutic approaches. Surgical excision is the treatment of choice for isolated, painful glomuvenous malformations. We describe a case of a 7-year-old girl with multiple glomuvenous malformations.

  3. Dermatology case

    Directory of Open Access Journals (Sweden)

    Sandrina Carvalho


    and self-limiting dermatosis with characteristic clinical and histopathological pattern that justify its designation. It is characterized by annular or arciform erythematous plaques, preferably affecting the extensor surface of upper and lower limbs of younger patients. There are four main variants of granuloma annulare: localized, generalized, subcutaneous and perforating. In childhood, localized and subcutaneous forms are most commonly observed. We describe the case of a seven-year-old girl with localized granuloma annulare.

  4. Dermatology Case

    Directory of Open Access Journals (Sweden)

    Catarina Matos


    Full Text Available The authors describe a clinical case of a 5-months-old boy with widespread rash since the first month of life. Diffuse papular rash with intensive itching. The shaved skin was inconclusive so we performed biopsy to conÞ rm the diagnosis of scabies. It’s a dermatosis very contagious caused by the mite Sarcoptes scabiei var. hominis. In infants skin eruption may have a polymorphic presentation with characteristic distribution.

  5. Case04

    DEFF Research Database (Denmark)

    Vestergaard, Flemming; Karlshøj, Jan; Hauch, Peter;

    Casestudiets formål er at beskrive og måle en større entreprenørvirksomheds omkostninger og gevin-ster ved at anvende metoder og værktøjer, der er modelbaserede. Case 04 tager udgangspunkt i et konkret byggeprojekt, hvor BIM teknologien er anvendt på et for den danske entreprenørbranche rela...

  6. Case Corabelle


    Hansen, Casper; Henriksen, Jesper; Loznica, Javor; Ragnarsson, Stefan; Hensing, Marcus


    This project explores the relation between organizational identity and online brands as formed through interaction and communication on online, social media through a case study of the cancelled music festival event Corabelle that was supposed to have been held in August of 2014. The investigation draws on the theories of Carlos Scolari and David A. Whetten to establish the relation between organizational identity and online brands, and the theories of Henry Jenkins and Jan H. Kietzmann in an...

  7. E-book Trial Using Handheld Devices Yields Mixed Reactions from Public Library Staff and Users in Essex County, UK. A review of: Dearnley, James, Cliff McKnight, and Anne Morris. “Electronic Book Usage in Public Libraries: A Study of User and Staff Reactions to a PDA-based Collection.” Journal of Librarianship and Information Science 36.4 (December 2004: 175‐82.

    Directory of Open Access Journals (Sweden)

    Stephanie Hall


    Full Text Available Objective - To assess e-book delivery on handheld devices provided to public library patrons, particularly housebound or visually impaired patrons and the users of a mobile library. Design - Product trial with a post-trial questionnaire for patrons and a post-trial focus group discussion among participating library staff. Setting - Mid-to-large size public library system in the United Kingdom. Subjects - 23 patrons participated; the number of library staff participating is not identified. Although the target population initially identified was housebound people, patrons reliant on the mobile library, and visually impaired people, the project team determined that it did not have sufficient funds to upgrade the PDAs to be compatible woth their preferred software for the visually impaired, and therefore this group was eliminated from the study. Lack of funds was also cited as a factor in the team being unable to provide assistive technology for those users suffering from arthritis, though this group was not excluded from the study. Just over half the patrons were aged 60+, and more than half were female. Two patrons self-identified as housebound. Methods - e-books were downloaded onto Hewlett Packard iPAQ 1910 Pdas by library staff and were loaned to participants between Janualry and April 2004. Although the authors of the study state that "creating staff champions was an important objective in this project" (p.176, it is unclear whether staff were screened for positive attitude towards e-Books. Prior to the trial, staff members were provided with training and orientation, and participants were asked for their font sna d reading preferences. Suport for participating patrons was available from staff or via an accompanying user manual, e-mail, or telephone help line. In a questionnaire adminsitered following the trial, participants were asked to respond to questions on the functionality of the handheld devices and e-book formats, positive and

  8. Dermatology Case

    Directory of Open Access Journals (Sweden)

    Sandrina Carvalho


    Full Text Available Connective tissue nevus (CTN is a hamartomatous growth which can be associated to multiple syndromes, such as tuberous sclerosis, Buschke-Ollendorf syndrome, or Proteus syndrome. Familial cases of CTN have also been related to cardiac disease. Classically, CTN are characterized by asymptomatic, firm, multiple, skin-colored or yellowish plaques on the trunk or limbs, arising during childhood with no gender preference. A skin biopsy is usually necessary to confirm the diagnosis. Additional studies are oriented by signs or symptoms suggesting an underlying disease.

  9. Case management. (United States)

    Rosenstein, A H; Propotnik, T


    Providing cost-effective high quality healthcare services ranks as the number one concern for anyone involved with the healthcare delivery system. While quality of care should always be the number one priority, controlling healthcare costs receives most of the attention. With limited healthcare dollars and providers assuming more of the financial risk for services rendered, a whole assortment of cost-containment strategies are being introduced in an effort to maintain some semblance of financial viability. Healthcare providers can approach cost control from two different angles. On the fixed-cost operational overhead side, traditional cost-containment techniques have focused on downsizing, maximizing productivity, staffing redesign, improved purchasing contracts, standardization, inventory control, and other more individualized restructured service models. On the variable-cost clinical side, cost control has been approached by introducing a variety of cost-containment strategies designed to improve efficiency and effectiveness of provider performance. While many of these strategies, previously discussed in the Journal of Healthcare Resource Management have stressed the importance of education, guidelines, pathways, and other clinical "tools for improvement," the success of many of these tools resides in the ability to provide real-time intervention. Real-time intervention rather than the more passive retrospective variance analysis has the greatest potential for producing cost savings by actually making a recommendation that prevents the unwanted event from occurring. In many institutions, the case manager bears the responsibility for monitoring and managing these programs. This article describes various case management models currently used by different institutions.

  10. Learners’ Perception on Security Issues in M-learning (Nigerian Universities Case Study

    Directory of Open Access Journals (Sweden)

    Shaibu Adekunle Shonola


    Full Text Available With the advent of modern technology, mobile phones and smartphones are used not only for calling and text messages but also for banking and social networking. Recent developments in technology have made the use of mobile devices feasible in other sectors such as education and government. While educators are using mobile devices as teaching aids, students are also using them as learning tools.  In some cases the developers of mobile learning in universities are making m-learning apps without serious consideration for security aspects whereas the handheld devices pose a serious threat to confidentiality, integrity and privacy of users including the learners. As a case study, this paper investigates the security concerns that students may have with the introduction of m-learning in higher education institutions in Nigeria and how this impacts on their learning. It examines the effects of security threats in m-learning on students and provides recommendations for alleviating these threats.Photo credit: "Sysop actions of la cabale camembière - croped" by PierreSelim - Own work. Licensed under Creative Commons Attribution 3.0 via Wikimedia Commons -

  11. Dermatology case

    Directory of Open Access Journals (Sweden)

    Susana Vilaça


    Full Text Available Tinea corporis is a dermatophyte infection of the body. It usually begins as a pruritic circular or oval erythematous scaling patch or plaque that spreads centrifugally. Multiple lesions may run together to produce “flower petal” configurations. Tinea corporis contracted from infected animals is often intensely inflammatory. The history and clinical picture combination is characteristic, but the diagnosis could be confirmed by KOH (potassium hydroxide examination of scrapings from the lesions. Tinea corporis usually responds to the daily application of topical antifungals, but systemic therapy is needed in patients who have failed topical therapy. We report a case of a two -year old girl with tinea corporis of the vulvar region, initially misdiagnosed as irritant diaper dermatitis.

  12. Case study

    DEFF Research Database (Denmark)

    Milana, Marcella; Bernt Sørensen, Tore

    of several DHSs. Furthermore ?Udspil? was chosen for being a non-formal learning activity based on individual participation, even though linked to institutionalized learning practices, which were carried out in cooperation between several local institutions.Last but not least, the project represents...... that time Roskilde University Centre and Learning Lab Denmark, DK)3. The case here presented is based on results from research activity carried out over a 1 year period (spring 2006 - spring 2007). Detailed information concerning participation in the project was collected in two DHSs only: the Sports Day......Learning for democratic citizenship is embedded in the general popular education ideal(folkeoplysning), which is the primary source of inspiration for the Day High Schools (DHSs). DHSs are private institutions supported by local authorities, that host primarily low educated and unemployed young...

  13. Endoscopic case

    Directory of Open Access Journals (Sweden)

    Fernando Pereira


    Full Text Available We present the case of a ten-year-old female patient referred to Gastroenterolgy consultation for abdominal pain and cramping, usually worse after eating, recurring diarrhoea, hypochromic and microcytic anaemia with low serum iron and ferritin levels. Moderate to severe Crohn’s disease of the terminal ileum e right colon (L3 was diagnosed, based on endoscopic image and biopsy. The patient was treated with prednisone and azathioprine, but after one year of treatment she was steroids dependent and treatment was switched to infliximab. One year after beginning this treatment, the patient achieved remission (clinical and laboratorial parameters. A control colonoscopy showed mucosal healing with scars and deformation with stenosis of ileocecal valve (Figures 1-2. Surgical intervention will be probably necessary in near future.

  14. The Integration of Handheld Technology and Science Curriculum for Primary School --On whether the Fish Can Live in the Wei He River in Xinxiang%手持技术与小学科学课程的整合——探究“新乡市区卫河水是否适合鱼类生长”

    Institute of Scientific and Technical Information of China (English)

    任改兰; 靳建华


    The notion of the new curriculum is that scientific learning should be focused on scientific inquiry and aims at utilizing and pre- serving water resource, so a new integrated practice activity is developed by using handheld technology to explore whether the fish can live in the Wei He River in Xinxiang. The integrated practice activity demonstrates how to effectively integrate handheld technology with science curric- ulum for primary school. It is not only used by schools in Xinxiang, but also offers references for other similar research - oriented learning. In science exploratory activity, students will acquire both knowledge and scientific researching method and their emotional attitudes and values will also get improved.%针对“水资源的利用和保护”,根据新课程“科学学习要以探究为核心”的理念,设计了利用手持技术探究卫河水是否适合鱼类生长的综合实践活动。该探究活动展示了手持技术如何与小学科学课程整合,可以直接为新乡市的学校所用,同时也为其他相似研究性学习提供参考。通过探究,学生不仅能习得相关的知识和探究的方法,其情感态度价值观目标也能得到进一步发展。

  15. Case Study: Testing with Case Studies (United States)

    Herreid, Clyde Freeman


    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue discusses using case studies to test for knowledge or lessons learned.

  16. Experimental study of the monitoring bias of pressure in intubation balloon using handheld pressure gauge%气囊压力表间断测量气囊压力值偏差的实验研究

    Institute of Scientific and Technical Information of China (English)

    林艳侠; 林丹; 陈碧群; 纪超; 袁从丽; 王宝春


    目的 探讨气囊压力表间断测量人工气道气囊压力时,测量值与实际值之间是否存在偏差、偏差来源和偏差大小,为气囊压力表的正确使用提供参考.方法 在实验室体外实验中,采用专用手持气囊压力表通过三通开关与人工气道气囊充气管线单向阀连接,通过三通的开关控制,测量气囊压力,得到测量值偏差后进行临床试验加以验证.研究对象为建立人工气道需行气囊压力监测的成人患者.结果 在实验室经过132次测量发现,手持压力表本身会造成气囊压力下降,称之为固有损失;充气值[(30.000±0.000) cmH2O,1 cmH2O=0.098 kPa]和测量值[(26.072±0.291)cmH2O]之间存在明显偏差,平均为(3.928±0.291)cmH2O(t=155.273,P=0.000);经过214次测量发现,充气管线单向阀在与压力表断开和连接的过程中造成气囊压力下降,称之为误差损失;充气值[(30.000±0.000) cmH2O]和测量值[(28.804±0.954) cmH2O]之间存在偏差,平均为(1.196±0.954) cmH2O(t=18.348,P=0.000).临床经过21 1次验证试验得到固有损失和误差损失两者之和,充气值[(30.000±0.000) cmH2O]和测量值[(24.730±2.583) cmH2O]之间同样存在偏差(即测量偏差),其值为(5.270±2.583) cmH2O(t=29.632,P=0.000).结论 使用气囊压力表进行间断测量气囊压力时,气囊原有的实际压力应为测量值与偏差值之和,且在连接前应先进行声门下吸引,以防止气囊上方分泌物因气囊体积缩小而滑向气道深部而引起误吸,并将气囊压力维持在30 cmH2O.%Objective To explore the bias between the real pressure and the measured values when handheld pressure gauge (HPG) was used to monitor intermittently the pressure in the intubation balloon,so as to provide some measures for the correct use of HPG.Methods In the first part of the study,HPG was used to measure the pressure with the balloon connected with a three-way tube with which to control the inflation and deflation in a

  17. A Case-Based Approach to Creative Design (United States)


    world and in to the hand-held personal communctr used in the Star Trek both, evolving concepts are used in the performtance task even television series...hav:ew copttoaddese laden of Together, these experiments indicate the util- analogica reasoning hvadrsedlaningo ity and effectiveness of our model

  18. Case Study: Writing a Journal Case Study (United States)

    Prud'homme-Genereux, Annie


    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue describes incorporating a journal article into the classroom by first converting it into a case study.

  19. Clinical Case Registries (CCR) (United States)

    Department of Veterans Affairs — The Clinical Case Registries (CCR) replaced the former Immunology Case Registry and the Hepatitis C Case Registry with local and national databases. The CCR:HIV and...

  20. Case Study Teaching (United States)

    Herreid, Clyde Freeman


    This chapter describes the history of case study teaching, types of cases, and experimental data supporting their effectiveness. It also describes a model for comparing the efficacy of the various case study methods. (Contains 1 figure.)



    Nediljka Gaurina-Međimurec


    Casing drilling is an alternative option to conventional drilling and uses standard oilfield casing instead of drillstring. This technology is one of the greatest developments in drilling operations. Casing drilling involves drilling and casing a well simultaneously. In casing driling process, downhole tools can be retrieved, through the casing on wire-line, meaning tool recovery or replacement of tools can take minutes versus hours under conventional methods. This process employs wireline-re...


    Directory of Open Access Journals (Sweden)

    Nediljka Gaurina-Međimurec


    Full Text Available Casing drilling is an alternative option to conventional drilling and uses standard oilfield casing instead of drillstring. This technology is one of the greatest developments in drilling operations. Casing drilling involves drilling and casing a well simultaneously. In casing driling process, downhole tools can be retrieved, through the casing on wire-line, meaning tool recovery or replacement of tools can take minutes versus hours under conventional methods. This process employs wireline-retrievable tools and a drill-lock assembly, permitting bit and BHA changes, coring, electrical logging and even directional or horizontal drilling. Once the casing point is reached, the casing is cemented in place without tripping pipe.

  3. Project management case studies

    CERN Document Server

    Kerzner, Harold R


    A new edition of the most popular book of project management case studies, expanded to include more than 100 cases plus a ""super case"" on the Iridium Project Case studies are an important part of project management education and training. This Fourth Edition of Harold Kerzner''s Project Management Case Studies features a number of new cases covering value measurement in project management. Also included is the well-received ""super case,"" which covers all aspects of project management and may be used as a capstone for a course. This new edition:Contains 100-plus case studies drawn from re

  4. PSS Case Book

    DEFF Research Database (Denmark)

    Neugebauer, Line Maria; Mougaard, Krestine; Andersen, Jakob Bejbro;

    The transformation process towards a PSS-oriented company is describes, through the presentation of the best practice cases. Each case describes motivations, challenges, business models and PSS offerings.......The transformation process towards a PSS-oriented company is describes, through the presentation of the best practice cases. Each case describes motivations, challenges, business models and PSS offerings....

  5. Case Based Reasoning: Case Representation Methodologies

    Directory of Open Access Journals (Sweden)

    Shaker H. El-Sappagh


    Full Text Available Case Based Reasoning (CBR is an important technique in artificial intelligence, which has been applied to various kinds of problems in a wide range of domains. Selecting case representation formalism is critical for the proper operation of the overall CBR system. In this paper, we survey and evaluate all of the existing case representation methodologies. Moreover, the case retrieval and future challenges for effective CBR are explained. Case representation methods are grouped in to knowledge-intensive approaches and traditional approaches. The first group overweight the second one. The first methods depend on ontology and enhance all CBR processes including case representation, retrieval, storage, and adaptation. By using a proposed set of qualitative metrics, the existing methods based on ontology for case representation are studied and evaluated in details. All these systems have limitations. No approach exceeds 53% of the specified metrics. The results of the survey explain the current limitations of CBR systems. It shows that ontology usage in case representation needs improvements to achieve semantic representation and semantic retrieval in CBR system.

  6. Medical student case presentation performance and perception when using mobile learning technology in the emergency department

    Directory of Open Access Journals (Sweden)

    Matthew Tews


    Full Text Available Hand-held mobile learning technology provides opportunities for clinically relevant self-instructional modules to augment traditional bedside teaching. Using this technology as a teaching tool has not been well studied. We sought to evaluate medical students’ case presentation performance and perception when viewing short, just-in-time mobile learning videos using the iPod touch prior to patient encounters.Twenty-two fourth-year medical students were randomized to receive or not to receive instruction by video, using the iPod Touch, prior to patient encounters. After seeing a patient, they presented the case to their faculty, who completed a standard data collection sheet. Students were surveyed on their perceived confidence and effectiveness after using these videos.Twenty-two students completed a total of 67 patient encounters. There was a statistically significant improvement in presentations when the videos were viewed for the first time (p = 0.032. There was no difference when the presentations were summed for the entire rotation (p = 0.671. The reliable (alpha = 0.97 survey indicated that the videos were a useful teaching tool and gave students more confidence in their presentations.Medical student patient presentations were improved with the use of mobile instructional videos following first time use, suggesting mobile learning videos may be useful in medical student education. If direct bedside teaching is unavailable, just-in-time iPod touch videos can be an alternative instructional strategy to improve first-time patient presentations by medical students.

  7. Comparative Test Case Specification

    DEFF Research Database (Denmark)

    Kalyanova, Olena; Heiselberg, Per

     This document includes a definition of the comparative test cases DSF200_3 and DSF200_4, which previously described in the comparative test case specification for the test cases DSF100_3 and DSF200_3 [Ref.1]....... This document includes a definition of the comparative test cases DSF200_3 and DSF200_4, which previously described in the comparative test case specification for the test cases DSF100_3 and DSF200_3 [Ref.1]....

  8. Effect of Latent Myofascial Trigger Points on Strength Measurements of the Upper Trapezius: A Case-Controlled Trial (United States)



    ABSTRACT Purpose: The purpose of this article was to determine whether strength is altered in the upper trapezius in the presence of latent myofascial trigger points (MTrP). Methods: This study was case controlled and used convenience sampling. The sample recruited was homogeneous with respect to age, sex, height, and body mass. Participants were assessed for the presence of latent MTrP in the upper trapezius and placed into two groups: an experimental group that had latent MTrP in the upper trapezius and a control group that did not. Eighteen women (mean age 21.4 y, SD 1.89; mean height 156.9 cm, SD 4.03; and mean body mass 51.7 kg, SD 5.84) made up the experimental group, and 19 women (mean age 20.3 y, SD 1.86; mean height 158.6 cm, SD 3.14; and mean body mass 53.2 kg, SD 5.17) made up the control group. We obtained strength measurements of the non-dominant arm using a handheld dynamometer and compared them between the two groups. Results: The difference in the strength measurements between the two groups was not statistically significant (p=0.59). Conclusions: The presence of latent MTrPs may not affect the strength of the upper trapezius. PMID:22942517

  9. Disaster Case Management (United States)

    U.S. Department of Health & Human Services — The Disaster Case Management Program (DCM) is a time-limited process that involves a partnership between a case manager and a disaster survivor (also known as a...

  10. Feasibibility study - cases

    DEFF Research Database (Denmark)

    Lund, Henrik; Hvelplund, Frede Kloster; Sukkumnoed, Decharut


    The chapter presents two case studies to show the tools of feasibiliy studies within the context of technological innovation.......The chapter presents two case studies to show the tools of feasibiliy studies within the context of technological innovation....

  11. FHEO Filed Cases (United States)

    Department of Housing and Urban Development — The dataset is a list of all the Title VIII fair housing cases filed by FHEO from 1/1/2007 - 12/31/2012 including the case number, case name, filing date, state and...

  12. Case Teaching and Evaluation (United States)

    Patton, Michael Quinn; Patrizi, Patricia


    Experience and reflection on experience are the best teachers, yet rich cases that capture experience for reflection have largely eluded professional training in evaluation. The absence of high-quality, readily available teaching cases has been an important gap in the field. This article reviews the benefits of case teaching, examines evaluation…

  13. Portal cholangiopathy: case report

    Directory of Open Access Journals (Sweden)

    Maria Cecilia Almeida Maia


    Full Text Available The present report describes the case of a child that after blunt abdominal trauma presented with portal thrombosis followed by progressive splenomegaly and jaundice. Ultrasonography and percutaneous cholangiography revealed biliary dilatation secondary to choledochal stenosis caused by dilated peribiliary veins, characterizing a case of portal biliopathy. The present case report is aimed at presenting an uncommon cause of this condition.

  14. Case study research. (United States)

    Taylor, Ruth; Thomas-Gregory, Annette


    This article describes case study research for nursing and healthcare practice. Case study research offers the researcher an approach by which a phenomenon can be investigated from multiple perspectives within a bounded context, allowing the researcher to provide a 'thick' description of the phenomenon. Although case study research is a flexible approach for the investigation of complex nursing and healthcare issues, it has methodological challenges, often associated with the multiple methods used in individual studies. These are explored through examples of case study research carried out in practice and education settings. An overview of what constitutes 'good' case study research is proposed.

  15. Defining a periodontitis case

    DEFF Research Database (Denmark)

    Baelum, Vibeke; Lopez, Rodrigo


    of the concomitant presence of CAL and BOP at the site level. Results The case definitions by Tonetti & Claffey and by Page & Eke yielded similar results, which were also quite similar to the results of simply identifying a case of periodontitis as a person having at least one site showing both CAL ≥ 4 mm and BOP....... Conclusions The results indicate that it should be feasible for the periodontal community to reach an agreement over the distinction between a case and a non-case. The classification system proposed by van der Velden is better suited for providing clinicians with a clear image of the case....

  16. Discussion on the Improvement of Security Functions of Railway Communication by the Hand-held Mobile Monitoring Positioning Terminal%手持移动监控定位终端改进铁路通信安全功能探讨

    Institute of Scientific and Technical Information of China (English)



    Through analyzing the existing problems of the monitoring and command of the original railway communication work, this paper expounds the functions of hand-held mobile monitoring positioning terminal to show that the application of monitor terminal system in railway communication system plays an important role in improving the emergency rescue of railway communication and the control of construction work and protecting the operation security of railway communication. The application of terminal greatly improves the working accuracy, shortens the time of failure treatment, reduces the economic losses caused by the faults and greatly improves the efficiency of railway communication. It is helpful to achieve the goal of value management.%本文通过分析原有铁路通信作业监控指挥存在的问题,阐述手持移动监控定位终端的功能,进而说明在铁路通信系统中应用监控终端系统,在改进铁路通信应急抢险和施工作业把控及铁路通信作业安全保障方面发挥的重要作用。终端的使用大大提高了作业精度,缩短了处理故障的时间,降低了故障造成的经济损失,从而大大提高铁路通信的效率,有助于实现价值管理的目标。

  17. Diffuse Optical Characterization of the Healthy Human Thyroid Tissue and Two Pathological Case Studies.

    Directory of Open Access Journals (Sweden)

    Claus Lindner

    Full Text Available The in vivo optical and hemodynamic properties of the healthy (n = 22 and pathological (n = 2 human thyroid tissue were measured non-invasively using a custom time-resolved spectroscopy (TRS and diffuse correlation spectroscopy (DCS system. Medical ultrasound was used to guide the placement of the hand-held hybrid optical probe. TRS measured the absorption and reduced scattering coefficients (μa, μs' at three wavelengths (690, 785 and 830 nm to derive total hemoglobin concentration (THC and oxygen saturation (StO2. DCS measured the microvascular blood flow index (BFI. Their dependencies on physiological and clinical parameters and positions along the thyroid were investigated and compared to the surrounding sternocleidomastoid muscle. The THC in the thyroid ranged from 131.9 μM to 144.8 μM, showing a 25-44% increase compared to the surrounding sternocleidomastoid muscle tissue. The blood flow was significantly higher in the thyroid (BFIthyroid = 16.0 × 10-9 cm2/s compared to the muscle (BFImuscle = 7.8 × 10-9 cm2/s, while StO2 showed a small (StO2, muscle = 63.8% to StO2, thyroid = 68.4%, yet significant difference. Two case studies with thyroid nodules underwent the same measurement protocol prior to thyroidectomy. Their THC and BFI reached values around 226.5 μM and 62.8 × 10-9 cm2/s respectively showing a clear contrast to the nodule-free thyroid tissue as well as the general population. The initial characterization of the healthy and pathologic human thyroid tissue lays the ground work for the future investigation on the use of diffuse optics in thyroid cancer screening.

  18. Haemospermia and 25 cases

    Directory of Open Access Journals (Sweden)

    Nikoubakht M


    Full Text Available During 3 years (1991-1994 25 cases were evaluated for hemospermia. 64% with primary management had improved. 36% that required more evaluation have at least one urologic problem in TRUS. Of these, adenocarcinoma of prostate, prostatic stone, seminal vesicle dilatation, each two cases, and verumontanum stone, urethral polyp, prostatic cyst each one case are diagnosed. According to this study the best method for evaluation of hemospermia is transrectal ultrasonography.

  19. Teaching Case: Enterprise Architecture Specification Case Study (United States)

    Steenkamp, Annette Lerine; Alawdah, Amal; Almasri, Osama; Gai, Keke; Khattab, Nidal; Swaby, Carval; Abaas, Ramy


    A graduate course in enterprise architecture had a team project component in which a real-world business case, provided by an industry sponsor, formed the basis of the project charter and the architecture statement of work. The paper aims to share the team project experience on developing the architecture specifications based on the business case…

  20. From Use Cases to Activity Cases

    DEFF Research Database (Denmark)

    Bækgaard, Lars


    Use cases can be used to capture requirements and to subdivide IT-systems into functionally coherent units. Information systems are activity systems that carry out important business activities. Many systems development methods recognize activity modeling as an important development activity. Use...

  1. Case-based reasoning

    CERN Document Server

    Kolodner, Janet


    Case-based reasoning is one of the fastest growing areas in the field of knowledge-based systems and this book, authored by a leader in the field, is the first comprehensive text on the subject. Case-based reasoning systems are systems that store information about situations in their memory. As new problems arise, similar situations are searched out to help solve these problems. Problems are understood and inferences are made by finding the closest cases in memory, comparing and contrasting the problem with those cases, making inferences based on those comparisons, and asking questions whe

  2. Commissioners' Monthly Case Activity Report (United States)

    Occupational Safety and Health Review Commission — Total cases pending at the beginning of the month, total cases added to the docket during the month, total cases disposed of during the month, and total cases...

  3. Examples and Case Studies

    NARCIS (Netherlands)

    Asbach, C.; Aguerre, O.; Bressot, C.; Brouwer, D.H.; Gommel, U.; Gorbunov, B.; Bihan, O. le; Jensen, K.A.; Kaminski, H.; Keller, M.; Koponen, I.K.; Kuhlbusch, T.A.J.; Lecloux, A.; Morgeneyer, M.; Muir, R.; Shandilya, N.; Stahlmecke, B.; Todea, A.M.


    Release of nanomaterials may occur during any stage of the life-cycle and can eventually lead to exposure to humans, the environment or products. Due to the large number of combinations of release processes and nanomaterials, release scenarios can currently only be tested on a case-by-case basis. Th

  4. Essential trichomegaly: case report

    Directory of Open Access Journals (Sweden)

    Julia Dutra Rossetto


    Full Text Available The present study reports two cases of symptomatic essential trichomegaly. Trichomegaly may develop in various diseases, including anorexia nervosa, hypothyroidism, pregnancy, pretibial myxedema, systemic lupus erythematosus, vernal keratoconjunctivitis, and uveitis. The exact incidence trichomegaly is unknown, and the condition remains sporadically reported. Two cases of symptomatic trichomegaly without any associated systemic disorder are presented in this paper.

  5. A Case Study of a Decision Support System on Mango Fruit Maturity

    NARCIS (Netherlands)

    Walsh, K.B.; Subedi, P.; Tijskens, L.M.M.


    Mango fruit maturity can be difficult to determine from external attributes. Assessment of parameters of fruit on tree (dry matter, internal flesh colour) relevant to estimation of fruit maturity was undertaken with a handheld (near infrared spectroscopic) system. Measurement error on dry matter was

  6. Adaptive technique for optic IRIG-B/FT3 codes and its application in handheld test device for smart substation%一种光IRIG-B/FT3码自适应技术及其在智能变电站测试仪器中的应用

    Institute of Scientific and Technical Information of China (English)

    石光; 赵勇; 杨经超; 孔圣立; 张道农; 韩伟; 张克声


    To accommodate a low cost, portable and intelligent requirement for test devices of electrical equipments, this paper proposes an adaptive technique for optic IRIG-B codes and FT3 sample value codes. Based on the different structure properties and bit rate between IRIG-B codes and FT3 codes, the technique can automatically recognize those two kinds of codes by processing the input stream through a serial port with high frequency clock signal. This technique extends the functions of test device for smart substation. The handheld test device using this technique has been successfully applied in the system test and field test for several smart substations. The test results demonstrate the validity and practicability of the proposed technique, which reduces the number of ports of test device with decreasing its power consumption and cost.%为适应电力设备测试仪器的低成本、智能化、便携化需求,提出了一种光 IRIG-B/FT3码自适应技术。该技术利用高频时钟对光串口IRIG-B/FT3码流进行处理,并根据两种输入码在编码特征和码流速率上的差异,自动识别光IRIG-B码报文和IEC60044-8(FT3)采样值报文,扩展了智能变电站测试仪器的功能。基于该技术研制的手持式智能变电站测试仪器,已成功应用于多个国内变电站的系统联调和现场测试。实测结果表明该技术的有效性和实用性,从而达到了减少测试仪器接口的数量、降低测试仪器功耗和成本的目的。

  7. Objectivist case study research

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Fachner, Jörg


    be achieved through the use of objectivist case study research. The strength of the case study design is that it allows for uncovering or suggesting causal relationships in real-life settings through an intensive and rich collection of data. According to Hilliard (1993), the opposite applies for extensive...... designs, in which a small amount of data is gathered on a large number of subjects. With the richness of data, the intensive design is ―the primary pragmatic reason for engaging in single-case or small N research‖ (p. 374) and for working from an idiographic rather than a nomothetic perspective....

  8. Some of the cases

    DEFF Research Database (Denmark)

    Eller, Nanna Hurwitz; Mogensen, Jørn Thykjær; Gyntelberg, Finn


    matched on age and gender. The cases had experienced significantly fewer incidents of violence and had less anxiety and flashback symptoms than the controls. The results suggest that the negative press coverage was the reason for the psychiatric symptoms rather than exposures at the workplace.......Some of the cases of acknowledged occupational psychiatric disorder in Denmark have been exposed to negative press coverage. Such individuals might have been exposed to violence to a lower extent than other with an acknowledged psychological work injury. We compared 25 cases with 35 controls...

  9. USCIS My Case Status (United States)

    Department of Homeland Security — USCIS provide a way for the public who applied for U.S. citizenship to check the status of their application online. To view the status of a case, the application...

  10. The Space for Case (United States)

    Shafto, Michael


    Research supported by grants from the National Institute of Mental Health, the National Science Foundation, and the Educational Testing Service; examines the psychological validity of Fillmore's theory of case grammar. (DD)

  11. Case report: Perinephric lymphangiomatosis

    Directory of Open Access Journals (Sweden)

    Gorantla Rajani


    Full Text Available Perirenal lymphangiomatosis is a rare benign malformation of the lymphatic system. We report here a case of bilateral perirenal and parapelvic involvement with a normal excretory collecting system.

  12. Recent Case Law

    DEFF Research Database (Denmark)

    Petz, Thomas; Sagaert, Vincent; Østergaard, Kim


    In this section authors from various European countries report the recent case law in their country on the field of private patrimonial law, that is decisions on the law of property, juridical acts, the law of obligations, contract law and prescription. The European Review of Private Law (ERPL......) started this section in 2003. The section aims to give our readers an overview of what is happening in the most recent European case law. We have asked the national reporters to report the juridical essence of the decisions given by the highest courts in their country. These national reports...... not relate the facts of the decision, nor the personal opinion of the reporter. One can find discussions on the most important decisions of European courts in ERPL’s case note section. The recent case law section gives overviews of decisions published in periods of four months. The period of January...

  13. Parathyroid carcinoma: case report (United States)



    Summary: The authors present a case of parathyroid carcinoma in a patient with primary hyperparathyroidism. Following a literature review, the clinical and diagnostic profile, treatment and prognosis of this rare disease are discussed. PMID:23837957





    Acromegaly is a rare disease caused due to hyper secretion of growth hormone. Most of the cases of acromegaly are caused by pitutary adenoma which can be microadenoma or macroadenomas. These adenomas are never malignant, but can have significant morbidity and mortality. We report a 35 year old female patient presented herewith classical presentation of acromegaly with chief complain of weight gain, excessive sweating , widening of both hands and feet and was diagnosed as a case of acromega...

  15. Autoerotic deaths: four cases. (United States)

    Cooke, C T; Cadden, G A; Margolius, K A


    We describe the circumstances and post mortem medical findings of 4 unusual fatalities where death occurred during autoerotic practice. Three cases occurred in young to middle-aged men--hanging, electrocution and inhalation of a zucchini. The manner of death in each was accidental. The fourth case was an elderly man who died of ischemic heart disease, apparently whilst masturbating with a vacuum cleaner and a hair dryer.

  16. Comparative Test Case Specification

    DEFF Research Database (Denmark)

    Kalyanova, Olena; Heiselberg, Per

    This document includes the specification on the IEA task of evaluation building energy simulation computer programs for the Double Skin Facades (DSF) constructions. There are two approaches involved into this procedure, one is the comparative approach and another is the empirical one. In the comp....... In the comparative approach the outcomes of different software tools are compared, while in the empirical approach the modelling results are compared with the results of experimental test cases. The comparative test cases include: ventilation, shading and geometry....

  17. Case for diagnosis


    Calistru,Ana Maria; Lisboa, Carmen; Bettencourt, Herberto; Azevedo, Filomena


    Riga-Fede disease is a rare, benign disorder characterized by reactive ulceration of the oral mucosa associated with repetitive dental traumatism. It was first described in children with neurologic disorders and is very rare in adults. This case report describes the occurrence of a large ulcer of the tongue, resembling squamous cell carcinoma, in an adult with hemiparesis. The lesion cleared after neurologic recovery. This case highlights the importance of considering this disorder in the dif...

  18. Evaluation of Ahura’s Firstdefender Handheld Chemical Identifier (United States)


    3.3 Trace Agent Investigation. When a molecule is adsorbed on a nanometer-scale roughed silver or gold surface, or is mixed with gold or silver nano ...SessionOO 1\\raw0 1 .spc Solid particula -te present, two layers milky on the bottom, somewhat miscible Session0O 1; scanO 10; match=2 PLAUSIBLE MATCHES

  19. A handheld computer-aided diagnosis system and simulated analysis (United States)

    Su, Mingjian; Zhang, Xuejun; Liu, Brent; Su, Kening; Louie, Ryan


    This paper describes a Computer Aided Diagnosis (CAD) system based on cellphone and distributed cluster. One of the bottlenecks in building a CAD system for clinical practice is the storage and process of mass pathology samples freely among different devices, and normal pattern matching algorithm on large scale image set is very time consuming. Distributed computation on cluster has demonstrated the ability to relieve this bottleneck. We develop a system enabling the user to compare the mass image to a dataset with feature table by sending datasets to Generic Data Handler Module in Hadoop, where the pattern recognition is undertaken for the detection of skin diseases. A single and combination retrieval algorithm to data pipeline base on Map Reduce framework is used in our system in order to make optimal choice between recognition accuracy and system cost. The profile of lesion area is drawn by doctors manually on the screen, and then uploads this pattern to the server. In our evaluation experiment, an accuracy of 75% diagnosis hit rate is obtained by testing 100 patients with skin illness. Our system has the potential help in building a novel medical image dataset by collecting large amounts of gold standard during medical diagnosis. Once the project is online, the participants are free to join and eventually an abundant sample dataset will soon be gathered enough for learning. These results demonstrate our technology is very promising and expected to be used in clinical practice.

  20. Swarm Optimization-Based Magnetometer Calibration for Personal Handheld Devices

    Directory of Open Access Journals (Sweden)

    Naser El-Sheimy


    Full Text Available Inertial Navigation Systems (INS consist of accelerometers, gyroscopes and a processor that generates position and orientation solutions by integrating the specific forces and rotation rates. In addition to the accelerometers and gyroscopes, magnetometers can be used to derive the user heading based on Earth’s magnetic field. Unfortunately, the measurements of the magnetic field obtained with low cost sensors are usually corrupted by several errors, including manufacturing defects and external electro-magnetic fields. Consequently, proper calibration of the magnetometer is required to achieve high accuracy heading measurements. In this paper, a Particle Swarm Optimization (PSO-based calibration algorithm is presented to estimate the values of the bias and scale factor of low cost magnetometers. The main advantage of this technique is the use of the artificial intelligence which does not need any error modeling or awareness of the nonlinearity. Furthermore, the proposed algorithm can help in the development of Pedestrian Navigation Devices (PNDs when combined with inertial sensors and GPS/Wi-Fi for indoor navigation and Location Based Services (LBS applications.