WorldWideScience

Sample records for cancer trends 1973-1995

  1. [Trend of cancer mortality in Hebei province, 1973-2013].

    Science.gov (United States)

    Liang, D; Li, D J; Shi, J; Zhang, Y C; Guo, T T; He, Y T

    2018-01-10

    Objective: To analyze the data of malignant tumor mortality and change in disease burden in Hebei province from 1973 to 2013. Methods: Cancer mortality rate, age-standardized mortality rate and the years of life lost due to premature mortality (YLLs) were calculated by using the data from three rounds of all death causes survey and database of cancer registry in Hebei during 1973-2013. Results: From 1973 to 2013, a linear upward of malignant tumor mortality was observed, with a 51.57% increase. The mortality rate during 1973-1975 was 98.52/100 000 and it was 149.33/100 000 during 2011-2013. During 1973-1975, the YLLs was 17.0/1 000 in males and 12.8/1 000 in females. While during 2011-2013, the YLLs was 23.2/1 000 in males and 15.9/1 000 in females. During 1973-1975, esophagus cancer, stomach cancer and liver cancer were top three leading causes of deaths. During 2011-2013, lung cancer, stomach cancer and liver cancer were main leading causes of deaths. During the past 40 years, the deaths of esophagus cancer and cervix cancer decreased dramatically, but the deaths of lung cancer and breast cancer increased sharply. Conclusions: The disease burden caused by malignant tumor is becoming more serious in Hebei. It is necessary to strengthen the primary prevention and screening of malignant tumor.

  2. An update in international trends in incidence rates of thyroid cancer, 1973-2007.

    Science.gov (United States)

    James, Benjamin C; Mitchell, Janeil M; Jeon, Heedo D; Vasilottos, Nektarios; Grogan, Raymon H; Aschebrook-Kilfoy, Briseis

    2018-05-01

    Over the past several decades, there has been a reported increase in the incidence of thyroid cancer in many countries. We previously reported an increase in thyroid cancer incidence across continents between 1973 and 2002. Here, we provide an update on the international trends in thyroid cancer between 2003 and 2007. We examined thyroid cancer incidence data from the Cancer Incidence in Five Continents (CI5) database for the period between 1973 and 2007 from 24 populations in the Americas, Asia, Europe, Africa and Oceania, and report on the time trends as well as the distribution by histologic type and gender worldwide. The incidence of thyroid cancer increased during the period from 1998-2002 to 2003-2007 in the majority of populations examined, with the highest rates observed among women, most notably in Israel and the United States SEER registry, at over 14 per 100,000 people. This update suggests that incidence is rising in a similar fashion across all regions of the world. The histologic and gender distributions in the updated CI5 are consistent with the previous report. Our analysis of the published CI5 data illustrates that the incidence of thyroid cancer increased between 1998-2002 and 2003-2007 in most populations worldwide, and rising rates continue in all regions of the world.

  3. Cancer in adolescents: Incidences and trends during 1995-2009 in Taiwan.

    Science.gov (United States)

    Hung, Giun-Yi; Chen, Chao-Chun; Horng, Jiun-Lin; Lin, Li-Yih

    2016-03-01

    This study aimed to describe cancer incidence rates and trends specifically for adolescents aged 15-19 years during 1995-2009 in Taiwan. The incidence counts and census data were obtained from the population-based Taiwan Cancer Registry. During the 15-year study period, 4122 adolescents were diagnosed with cancer. The overall incidence rate was 155.2 per million person-years. Other epithelial tumors were the most frequently diagnosed cancer group (23.7%), followed by leukemias (18.0%) and lymphomas (13.9%). When compared to rates in Western countries, a significantly low rate of lymphomas was found. Moreover, rates of the subtypes of melanomas and nasopharyngeal carcinomas being 1/10- and 4-times rates in Western countries were the most striking variations. During 1995-2009, the overall rate of adolescent cancer did not significantly change. However, the most significant upward and declining trends in incidence rates were found for male germ cell neoplasms (annual percent change, APC, 6.4%) and hepatic tumors (APC, -11.1%), respectively. Further investigation and enhancement of the public discourse of possible lifestyle and environmental risk factors associated with increasing trends of certain adolescent cancers should be carried out in Taiwan. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  4. Historical Trends in the Use of Radiation Therapy for Pediatric Cancers: 1973-2008

    International Nuclear Information System (INIS)

    Jairam, Vikram; Roberts, Kenneth B.; Yu, James B.

    2013-01-01

    Purpose: This study was undertaken to assess historical trends in the use of radiation therapy (RT) for pediatric cancers over the past 4 decades. Methods: The National Cancer Institute's Surveillance, Epidemiology, and End Results database of the 9 original tumor registries (SEER-9) was queried to identify patients aged 0 to 19 years with acute lymphoblastic leukemia, acute myeloid leukemia, bone and joint cancer, cancer of the brain and nervous system, Hodgkin lymphoma, neuroblastoma, non-Hodgkin lymphoma, soft tissue cancer, Wilms tumor, or retinoblastoma from 1973 to 2008. Patients were grouped into 4-year time epochs. The number and percentage of patients who received RT as part of their initial treatment were calculated per epoch by each diagnosis group from 1973 to 2008. Results: RT use for acute lymphoblastic leukemia, non-Hodgkin lymphoma, and retinoblastoma declined sharply from 57%, 57%, and 30% in 1973 to 1976 to 11%, 15%, and 2%, respectively, in 2005 to 2008. Similarly, smaller declines in RT use were also seen in brain cancer (70%-39%), bone cancer (41%-21%), Wilms tumor (75%-53%), and neuroblastoma (60%-25%). RT use curves for Wilms tumor and neuroblastoma were nonlinear with nadirs in 1993 to 1996 at 39% and 19%, respectively. There were minimal changes in RT use for Hodgkin lymphoma, soft tissue cancer, or acute myeloid leukemia, roughly stable at 72%, 40%, and 11%, respectively. Almost all patients treated with RT were given external beam RT exclusively. However, from 1985 to 2008, treatments involving brachytherapy, radioisotopes, or combination therapy increased in frequency, comprising 1.8%, 4.6%, and 11.9% of RT treatments in brain cancer, soft tissue cancer, and retinoblastoma, respectively. Conclusions: The use of RT is declining over time in 7 of 10 pediatric cancer categories. A limitation of this study is a potential under-ascertainment of RT use in the SEER-9 database including the delayed use of RT

  5. Historical Trends in the Use of Radiation Therapy for Pediatric Cancers: 1973-2008

    Energy Technology Data Exchange (ETDEWEB)

    Jairam, Vikram [Yale School of Medicine, Department of Therapeutic Radiology, New Haven, Connecticut (United States); Roberts, Kenneth B. [Yale School of Medicine, Department of Therapeutic Radiology, New Haven, Connecticut (United States); Yale Cancer Center, New Haven, Connecticut (United States); Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center at Yale, New Haven, Connecticut (United States); Yu, James B., E-mail: james.b.yu@yale.edu [Yale School of Medicine, Department of Therapeutic Radiology, New Haven, Connecticut (United States); Yale Cancer Center, New Haven, Connecticut (United States); Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center at Yale, New Haven, Connecticut (United States)

    2013-03-01

    Purpose: This study was undertaken to assess historical trends in the use of radiation therapy (RT) for pediatric cancers over the past 4 decades. Methods: The National Cancer Institute's Surveillance, Epidemiology, and End Results database of the 9 original tumor registries (SEER-9) was queried to identify patients aged 0 to 19 years with acute lymphoblastic leukemia, acute myeloid leukemia, bone and joint cancer, cancer of the brain and nervous system, Hodgkin lymphoma, neuroblastoma, non-Hodgkin lymphoma, soft tissue cancer, Wilms tumor, or retinoblastoma from 1973 to 2008. Patients were grouped into 4-year time epochs. The number and percentage of patients who received RT as part of their initial treatment were calculated per epoch by each diagnosis group from 1973 to 2008. Results: RT use for acute lymphoblastic leukemia, non-Hodgkin lymphoma, and retinoblastoma declined sharply from 57%, 57%, and 30% in 1973 to 1976 to 11%, 15%, and 2%, respectively, in 2005 to 2008. Similarly, smaller declines in RT use were also seen in brain cancer (70%-39%), bone cancer (41%-21%), Wilms tumor (75%-53%), and neuroblastoma (60%-25%). RT use curves for Wilms tumor and neuroblastoma were nonlinear with nadirs in 1993 to 1996 at 39% and 19%, respectively. There were minimal changes in RT use for Hodgkin lymphoma, soft tissue cancer, or acute myeloid leukemia, roughly stable at 72%, 40%, and 11%, respectively. Almost all patients treated with RT were given external beam RT exclusively. However, from 1985 to 2008, treatments involving brachytherapy, radioisotopes, or combination therapy increased in frequency, comprising 1.8%, 4.6%, and 11.9% of RT treatments in brain cancer, soft tissue cancer, and retinoblastoma, respectively. Conclusions: The use of RT is declining over time in 7 of 10 pediatric cancer categories. A limitation of this study is a potential under-ascertainment of RT use in the SEER-9 database including the delayed use of RT.

  6. Historical trends in the use of radiation therapy for pediatric cancers: 1973-2008.

    Science.gov (United States)

    Jairam, Vikram; Roberts, Kenneth B; Yu, James B

    2013-03-01

    This study was undertaken to assess historical trends in the use of radiation therapy (RT) for pediatric cancers over the past 4 decades. The National Cancer Institute's Surveillance, Epidemiology, and End Results database of the 9 original tumor registries (SEER-9) was queried to identify patients aged 0 to 19 years with acute lymphoblastic leukemia, acute myeloid leukemia, bone and joint cancer, cancer of the brain and nervous system, Hodgkin lymphoma, neuroblastoma, non-Hodgkin lymphoma, soft tissue cancer, Wilms tumor, or retinoblastoma from 1973 to 2008. Patients were grouped into 4-year time epochs. The number and percentage of patients who received RT as part of their initial treatment were calculated per epoch by each diagnosis group from 1973 to 2008. RT use for acute lymphoblastic leukemia, non-Hodgkin lymphoma, and retinoblastoma declined sharply from 57%, 57%, and 30% in 1973 to 1976 to 11%, 15%, and 2%, respectively, in 2005 to 2008. Similarly, smaller declines in RT use were also seen in brain cancer (70%-39%), bone cancer (41%-21%), Wilms tumor (75%-53%), and neuroblastoma (60%-25%). RT use curves for Wilms tumor and neuroblastoma were nonlinear with nadirs in 1993 to 1996 at 39% and 19%, respectively. There were minimal changes in RT use for Hodgkin lymphoma, soft tissue cancer, or acute myeloid leukemia, roughly stable at 72%, 40%, and 11%, respectively. Almost all patients treated with RT were given external beam RT exclusively. However, from 1985 to 2008, treatments involving brachytherapy, radioisotopes, or combination therapy increased in frequency, comprising 1.8%, 4.6%, and 11.9% of RT treatments in brain cancer, soft tissue cancer, and retinoblastoma, respectively. The use of RT is declining over time in 7 of 10 pediatric cancer categories. A limitation of this study is a potential under-ascertainment of RT use in the SEER-9 database including the delayed use of RT. Copyright © 2013 Elsevier Inc. All rights reserved.

  7. Trends in primary surgical and radiation therapy for localized breast cancer in the detroit metropolitan area 1973-1992

    International Nuclear Information System (INIS)

    Chuba, Paul J.; Simon, Michael S.

    1997-01-01

    Purpose: The purpose of this report is to describe trends in primary surgical and radiation therapy for localized breast cancer from 1973 through 1992 among residents of the Detroit Metropolitan area. Methods and Materials: Data on surgical and radiation therapy procedures for women with local stage breast cancer were obtained from the population-based Metropolitan Detroit Cancer Surveillance System (MDCSS). Results: Women age 75 years and older were treated less aggressively than younger women (< age 75) as evidenced by higher rates of simple mastectomy or no treatment among older women. Younger women (< age 75) were more likely to have had optimal breast conservation therapy which consisted of partial mastectomy, axillary lymph node dissection (ALND), and radiation therapy, than were women who were older than 75. Partial mastectomy has increased proportionally from 4% of all breast cancer surgeries in the time period 1973 to 1977, to 39% of all surgeries from 1988 through 1992. Conclusion: A marked difference in surgical treatment of breast cancer exists for younger vs. older women. Despite changes in surgical treatment trends for breast cancer, a large proportion of women who are candidates for conservative therapy continue to undergo mastectomy

  8. Trends in mouth cancer incidence in Mumbai, India (1995-2009): An age-period-cohort analysis.

    Science.gov (United States)

    Shridhar, Krithiga; Rajaraman, Preetha; Koyande, Shravani; Parikh, Purvish M; Chaturvedi, Pankaj; Dhillon, Preet K; Dikshit, Rajesh P

    2016-06-01

    Despite tobacco control and health promotion efforts, the incidence rates of mouth cancer are increasing across most regions in India. Analysing the influence of age, time period and birth cohort on these secular trends can point towards underlying factors and help identify high-risk populations for improved cancer control programmes. We evaluated secular changes in mouth cancer incidence among men and women aged 25-74 years in Mumbai between 1995 and 2009 by calculating age-specific and age-standardized incidence rates (ASR). We estimated the age-adjusted linear trend for annual percent change (EAPC) using the drift parameter, and conducted an age-period-cohort (APC) analysis to quantify recent time trends and to evaluate the significance of birth cohort and calendar period effects. Over the 15-year period, age-standardized incidence rates of mouth cancer in men in Mumbai increased by 2.7% annually (95% CI:1.9 to 3.4), pMumbai cancer registry indicate a significant linear increase of mouth cancer incidence from 1995 to 2009 in men, which was driven by younger men aged 25-49 years, and a non-significant upward trend in similarly aged younger women. Health promotion efforts should more effectively target younger cohorts. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  9. Incidence trends of human papillomavirus-related head and neck cancer in Taiwan, 1995-2009.

    Science.gov (United States)

    Hwang, Tzer-Zen; Hsiao, Jenn-Ren; Tsai, Chia-Rung; Chang, Jeffrey S

    2015-07-15

    Recent studies suggested that human papillomavirus (HPV) is an emerging risk factor of head and neck cancer (HNC), particularly for oropharyngeal cancer. Studies from the West showed a rising trend of HPV-related HNC despite a decrease of the overall HNC incidence. In contrast, the overall HNC incidence in Taiwan has continued to rise. It is not clear whether the incidence trends of HPV-related HNC in Taiwan have a similar pattern to those from countries with an overall decreasing incidence of HNC. This study examined the incidence trends of HPV-related and HPV-unrelated HNC in Taiwan using data from the Taiwan Cancer Registry. Our results showed that the incidence trends of HPV-related and HPV-unrelated HNC in Taiwan both rose during 1995-2009. The incidence of HPV-related HNC (1.3 per 100,000 in 1995 to 3.3 in 2009, annual percentage change (APC) = 6.9, p Taiwan has continued to increase, the most rapid rise is in the HPV-related HNC. This suggests that similar to the Western world, HPV-related HNC is becoming an important public health issue in Taiwan. © 2014 UICC.

  10. International patterns and trends in testicular cancer incidence, overall and by histologic subtype, 1973-2007.

    Science.gov (United States)

    Trabert, B; Chen, J; Devesa, S S; Bray, F; McGlynn, K A

    2015-01-01

    Incidence rates of testicular cancer in Northern European and North American countries have been widely reported, whereas rates in other populations, such as Eastern Europe, Central/South America, Asia, and Africa, have been less frequently evaluated. We examined testicular cancer incidence rates overall and by histologic type by calendar time and birth cohort for selected global populations 1973-2007. Age-standardized incidence rates over succeeding 5-year periods were calculated from volumes 4-9 of Cancer Incidence in Five Continents electronic database (CI5plus) and the newly released CI5X (volume 10) database. Annual percent change over the 35-year period was calculated using weighted least squares regression. Age-period-cohort analyses were performed and observed rates and fitted rate ratios presented by birth cohort. Incidence rates of testicular cancer increased between 1973-1977 and 2003-2007 in most populations evaluated worldwide. Of note, incidence rates in Eastern European countries rose rapidly and approached rates in Northern European countries. Rates in Central and South America also increased and are now intermediate to the high rates among men of European ancestry and low rates among men of Asian or African descent. Some heterogeneity in the trends in seminoma and nonseminoma were observed in Denmark, the United Kingdom, and among US whites, particularly in recent generations, with rapid and uniform increases in the incidence of both histologic types in Slovakia. Reasons for the rising incidence rates among European and American populations remain unexplained; however, changing distributions in the prevalence of risk factors for testicular cancer cannot be ruled out. © 2014 American Society of Andrology and European Academy of Andrology.

  11. Oropharyngeal squamous cell carcinoma incidence and mortality trends in the United States, 1973-2013.

    Science.gov (United States)

    Megwalu, Uchechukwu C; Sirjani, Davud; Devine, Erin E

    2017-10-31

    To analyze oropharyngeal squamous cell carcinoma incidence and mortality trends in the United States for the years 1973 through 2013. Cross-sectional study using a large population-based cancer database. Data on incidence and mortality rates were extracted from the Surveillance, Epidemiology, and End Results (SEER) 9 Database. Annual percentage change in rates was calculated using Joinpoint regression analysis (National Cancer Institute, Bethesda, MD). Incidence rates increased (annual percent change [APC]; 1.52, 95% confidence interval [CI] 0.17 to 2.88) from 1973 to 1983, remained stable (APC -0.52, 95% CI -1.30 to 0.26) from 1983 to 1997, and increased (APC 1.32, 95% CI 0.83 to 1.81) from 1997 to 2013. Overall, incidence rates increased for males (APC 0.73, 95% CI 0.22 to 1.25) but not females (APC -0.77, 95% CI -0.68 to 0.82). Incidence rates increased in the white population (APC 0.79, 95% CI 0.33 to 1.25) but decreased in the black population (APC -0.72, 95% CI -1.41 to -0.02). The incidence rates increased for tongue-base tumors (APC 1.17, 95% CI 0.42 to 1.92) and tonsil tumors (APC 0.47, 95% CI 1.10 to 4.96) but decreased for other sites. Incidence-based mortality decreased (APC -0.78, 95% CI -1.13 to -0.42) from 1993 to 2013. Oropharyngeal squamous cell carcinoma incidence rates increased in a nonlinear fashion from 1973 to 2013, whereas mortality rates declined. This, along with variation in trends by demographic and tumor factors, suggest that human papilloma virus is the main driver of the recent rise in incidence. 2b. Laryngoscope, 2017. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

  12. Temporal Trends in Geographical Variation in Breast Cancer Mortality in China, 1973-2005: An Analysis of Nationwide Surveys on Cause of Death.

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    Xia, Changfa; Kahn, Clare; Wang, Jinfeng; Liao, Yilan; Chen, Wanqing; Yu, Xue Qin

    2016-09-28

    To describe geographical variation in breast cancer mortality over time, we analysed breast cancer mortality data from three retrospective national surveys on causes of death in recent decades in China. We first calculated the age-standardized mortality rate (ASMR) for each of the 31 provinces in mainland China stratified by survey period (1973-1975, 1990-1992 and 2004-2005). To test whether the geographical variation in breast cancer mortality changed over time, we then estimated the rate ratio (RR) for the aggregated data for seven regions and three economic zones using generalized linear models. Finally, we examined the correlation between mortality rate and several macro-economic measures at the provincial level. We found that the overall ASMR increased from 2.98 per 100,000 in 1973-1975 to 3.08 per 100,000 in 1990-1992, and to 3.85 per 100,000 in 2004-2005. Geographical variation in breast cancer mortality also increased significantly over time at the regional level ( p = 0.002) but not at the economic zone ( p = 0.089) level, with RR being generally lower for Western China (Northwest and Southwest) and higher in Northeast China over the three survey periods. These temporal and spatial trends in breast cancer mortality were found to be correlated with per capita gross domestic product, number of hospitals and health centres' beds per 10,000 population and number of practicing doctors per 10,000 population, and average number of live births for women aged 15-64. It may be necessary to target public health policies in China to address the widening geographic variation in breast cancer mortality, and to take steps to ensure that the ease of access and the quality of cancer care across the country is improved for all residents.

  13. Temporal Trends in Geographical Variation in Breast Cancer Mortality in China, 1973–2005: An Analysis of Nationwide Surveys on Cause of Death

    Directory of Open Access Journals (Sweden)

    Changfa Xia

    2016-09-01

    Full Text Available To describe geographical variation in breast cancer mortality over time, we analysed breast cancer mortality data from three retrospective national surveys on causes of death in recent decades in China. We first calculated the age-standardized mortality rate (ASMR for each of the 31 provinces in mainland China stratified by survey period (1973–1975, 1990–1992 and 2004–2005. To test whether the geographical variation in breast cancer mortality changed over time, we then estimated the rate ratio (RR for the aggregated data for seven regions and three economic zones using generalized linear models. Finally, we examined the correlation between mortality rate and several macro-economic measures at the provincial level. We found that the overall ASMR increased from 2.98 per 100,000 in 1973–1975 to 3.08 per 100,000 in 1990–1992, and to 3.85 per 100,000 in 2004–2005. Geographical variation in breast cancer mortality also increased significantly over time at the regional level (p = 0.002 but not at the economic zone (p = 0.089 level, with RR being generally lower for Western China (Northwest and Southwest and higher in Northeast China over the three survey periods. These temporal and spatial trends in breast cancer mortality were found to be correlated with per capita gross domestic product, number of hospitals and health centres’ beds per 10,000 population and number of practicing doctors per 10,000 population, and average number of live births for women aged 15–64. It may be necessary to target public health policies in China to address the widening geographic variation in breast cancer mortality, and to take steps to ensure that the ease of access and the quality of cancer care across the country is improved for all residents.

  14. Temporal Trends in Geographical Variation in Breast Cancer Mortality in China, 1973–2005: An Analysis of Nationwide Surveys on Cause of Death

    Science.gov (United States)

    Xia, Changfa; Kahn, Clare; Wang, Jinfeng; Liao, Yilan; Chen, Wanqing; Yu, Xue Qin

    2016-01-01

    To describe geographical variation in breast cancer mortality over time, we analysed breast cancer mortality data from three retrospective national surveys on causes of death in recent decades in China. We first calculated the age-standardized mortality rate (ASMR) for each of the 31 provinces in mainland China stratified by survey period (1973–1975, 1990–1992 and 2004–2005). To test whether the geographical variation in breast cancer mortality changed over time, we then estimated the rate ratio (RR) for the aggregated data for seven regions and three economic zones using generalized linear models. Finally, we examined the correlation between mortality rate and several macro-economic measures at the provincial level. We found that the overall ASMR increased from 2.98 per 100,000 in 1973–1975 to 3.08 per 100,000 in 1990–1992, and to 3.85 per 100,000 in 2004–2005. Geographical variation in breast cancer mortality also increased significantly over time at the regional level (p = 0.002) but not at the economic zone (p = 0.089) level, with RR being generally lower for Western China (Northwest and Southwest) and higher in Northeast China over the three survey periods. These temporal and spatial trends in breast cancer mortality were found to be correlated with per capita gross domestic product, number of hospitals and health centres’ beds per 10,000 population and number of practicing doctors per 10,000 population, and average number of live births for women aged 15–64. It may be necessary to target public health policies in China to address the widening geographic variation in breast cancer mortality, and to take steps to ensure that the ease of access and the quality of cancer care across the country is improved for all residents. PMID:27690073

  15. Evolução da mortalidade por neoplasias malignas no Rio Grande do Sul, 1979-1995 Time trends in cancer mortality in Rio Grande do Sul, Brazil, 1979-1995

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    Ana Luiza Curi Hallal

    2001-11-01

    Full Text Available Foi analisada a mortalidade por câncer no Rio Grande do Sul (RS, entre 1979 e 1995. As variáveis consideradas foram sexo, idade, ano de ocorrência do óbito e causa básica da morte. Para análise da tendência das taxas padronizadas de mortalidade (método direto, população padrão: RS-1996 foi utilizada a regressão linear simples. As localizações mais freqüentes do tumor foram: pulmão, esôfago, próstata, estômago e cólon/reto, nos homens, e mama, colo do útero/útero não especificado, pulmão, cólon/reto e estômago, nas mulheres. A tendência temporal das taxas padronizadas de mortalidade, em cada sexo, do ponto de vista estatístico, foi de estabilidade, bem como por câncer de cólon/reto feminino e de colo do útero/útero não especificado. Verificou-se tendência estatisticamente significativa de crescimento da mortalidade por câncer de pulmão, em ambos os sexos, mama feminina, próstata e cólon/reto masculino; e, da mesma forma, decréscimo por câncer de estômago, para ambos os sexos, e esôfago, para os homens.The aim of this study was to analyze cancer mortality in Rio Grande do Sul (RS, Brazil, during the period from1979 to 1995. Study variables were sex, age, year and underlying cause of death. The simple linear regression technique was used to evaluate the trend of standardized death rates (direct method, using the population of RS in 1996 as the standard. The most frequent sites of tumors in males were lung, esophagus, prostate, stomach and colon/rectum; in females they were breast, cervix of the uterus, lung, colon/rectum and stomach. Standardized death rates presented a stable trend for all malignant neoplasms in both sexes, as did cancer of cervix of the uterus/ non-specified uterus and colon/rectum tumors in females. A significant rising trend was observed in mortality rates due to lung cancer in both sexes, breast cancer in females, prostate and colon/rectum cancer in males. The rates of stomach cancer

  16. Natural gas 1995: Issues and trends

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    Natural Gas 1995: Issues and Trends addresses current issues affecting the natural gas industry and markets. Highlights of recent trends include: Natural gas wellhead prices generally declined throughout 1994 and for 1995 averages 22% below the year-earlier level; Seasonal patterns of natural gas production and wellhead prices have been significantly reduced during the past three year; Natural gas production rose 15% from 1985 through 1994, reaching 18.8 trillion cubic feet; Increasing amounts of natural gas have been imported; Since 1985, lower costs of producing and transporting natural gas have benefitted consumers; Consumers may see additional benefits as States examine regulatory changes aimed at increasing efficiency; and, The electric industry is being restructured in a fashion similar to the recent restructuring of the natural gas industry.

  17. A comparative population-based study of prostate cancer incidence and mortality rates in Singapore, Sweden and Geneva, Switzerland from 1973 to 2006

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    Chen Cynthia

    2012-06-01

    Full Text Available Abstract Background Prostate cancer is the most commonly diagnosed malignancy in men in Sweden and Geneva, and the third most common in men in Singapore. This population-based study describes trends in the incidence and mortality rates of prostate cancer in Singapore, Sweden and Geneva (Switzerland from 1973 to 2006 and explores possible explanations for these different trends. Methods Data from patients diagnosed with prostate cancer were extracted from national cancer registries in Singapore (n = 5,172, Sweden (n = 188,783 and Geneva (n = 5,755 from 1973 to 2006. Trends of incidence and mortality were reported using the Poisson and negative binomial regression models. The age, period and birth-cohort were tested as predictors of incidence and mortality rates of prostate cancer. Results Incidence rates of prostate cancer increased over all time periods for all three populations. Based on the age-period-cohort analysis, older age and later period of diagnosis were associated with a higher incidence of prostate cancer, whereas older age and earlier period were associated with higher mortality rates for prostate cancer in all three countries. Conclusions This study demonstrated an overall increase in incidence rates and decrease in mortality rates in Singapore, Sweden and Geneva. Both incidence and mortality rates were much lower in Singapore. The period effect is a stronger predictor of incidence and mortality of prostate cancer than the birth-cohort effect.

  18. Analyzing Trends in Subjective Well-Being in 15 European Countries, 1973-2002

    DEFF Research Database (Denmark)

    Bjørnskov, Christian; Gupta, Nabanita Datta; Pedersen, Peder J.

    2008-01-01

    by exploiting a long and complete time-series from the Eurobarometer Survey, 1973-2002 allowing an examination of trends in life satisfaction across 15 European countries employing a modified version of Kendall's Tau. Our results show that while current GDP growth does not affect trends in well......-being, accelerations in GDP growth do. In addition, faster GDP growth and faster growth of government consumption than in neighbouring countries induces positive trends in life satisfaction. Our findings are consistent with the predictions of aspirations theory and the theory of reference group comparisons.  ...

  19. Incidence and mortality trends of gastric and colorectal cancers in Croatia, 1988-2008

    Science.gov (United States)

    Kirac, Iva; Šekerija, Mario; Šimunović, Iva; Zgaga, Lina; Vrdoljak, Danko Velimir; Kovačević, Dujo; Kuliš, Tomislav; Znaor, Ariana

    2012-01-01

    Aim To estimate the incidence and mortality trends of gastric and colorectal cancers in Croatia between 1988 and 2008. Methods Incidence data for the period 1988-2008 were obtained from the Croatian National Cancer Registry. The number of deaths from gastric and colorectal cancers was obtained from the World Health Organization mortality database. Joinpoint regression analysis was used to describe changes in trends by sex. Results Gastric cancer incidence rates declined steadily during the study period, with estimated annual percent change (EAPC) of -3.2% for men and -2.8% for women. Mortality rates in men decreased, with EAPC of -5.0% from 1988-1995 and -2.5% from 1995-2008. Mortality rates in women decreased, with EAPC of -3.2% throughout the study period. For colorectal cancer in men, joinpoint analysis revealed increasing trends of both incidence (EAPC 2.9%) and mortality (EAPC 2.1%).In women, the increase in incidence was not significant, but mortality in the last 15 years showed a significant increase of 1.1%. Conclusion The incidence and mortality trends of gastric cancer in Croatia are similar to other European countries, while the still increasing colorectal cancer mortality calls for more efficient prevention and treatment. PMID:22522990

  20. Spatial variations of summer precipitation trends in South Korea, 1973-2005

    International Nuclear Information System (INIS)

    Chang, Heejun; Kwon, Won-Tae

    2007-01-01

    We have investigated the spatial patterns of trends in summer precipitation amount, intensity, and heavy precipitation for South Korea between 1973 and 2005. All stations show increasing trends in precipitation amount during the summer months, with the highest percentage of significant increase in June precipitation for the northern and central western part of South Korea. There is a significant increase in August precipitation for stations in the southeastern part of South Korea. Only a few stations exhibited significant upward trends in September precipitation. There is a weak to moderate spatial autocorrelation with the highest Moran's I value in June precipitation amount and August precipitation intensity. The number of days with daily precipitation exceeding 50 and 30 mm during the summer has increased at all stations. Observed trends are likely to be associated with changes in large-scale atmospheric circulation, sea surface temperature anomalies, and orography, but detailed causes of these trends need further investigation

  1. Trends in colorectal cancer survival in northern Denmark: 1985-2004

    DEFF Research Database (Denmark)

    Iversen, Lene Hjerrild; Nørgaard, Mette; Jepsen, Peter

    2007-01-01

    OBJECTIVE: The prognosis for colorectal cancer (CRC) is less favourable in Denmark than in neighbouring countries. To improve cancer treatment in Denmark, a National Cancer Plan was proposed in 2000. We conducted this population-based study to monitor recent trends in CRC survival and mortality...... for age and gender. A total of 19,515 CRC patients were identified and linked with the Central Office of Civil Registration to ascertain survival through January 2005. Results: From 1985 to 2004, 1-year and 5-year survival improved both for patients with colon and rectal cancer. From 1995-1999 to 2000......-2004, overall 1-year survival of 65% for colon cancer did not improve, and some age groups experienced a decreasing 1-year survival probability. For rectal cancer, overall 1-year survival increased from 71% in 1995-1999 to 74% in 2000-2004. Using 1985-1989 as reference period, 30-day mortality did not decrease...

  2. Cancer mortality among immigrant populations in Ontario, 1969 through 1973.

    OpenAIRE

    Newman, A. M.; Spengler, R. F.

    1984-01-01

    Ontario is home to a sizeable, recently established immigrant population whose cancer mortality has until now remained unexamined. The province's six largest immigrant groups (British, Italian, German, Dutch, Polish and Soviet) were investigated to compare their cancer mortality experience with that prevailing in Ontario and in their countries of birth for the period 1969 through 1973. Standardized mortality ratios (SMRs) were computed from data from Statistics Canada and the World Health Org...

  3. [Soil-transmitted helminth trends and prevalence in La Virgen, Colombia 1995-2005].

    Science.gov (United States)

    Fernández-Niño, Julián A; Reyes-Harker, Patricia; Moncada-Alvarez, Ligia I; López, Myriam C; Cháves, María Del Pilar; Knudson, Angélica; Ariza, Yoseth

    2007-01-01

    Describing soil-transmitted helminthiasis prevalence and trends in children aged less than 15 in the village of La Virgen, Cundinamarca. Three non-random surveys were carried out on school-children aged 0 to 15 years. Intestinal parasitism was determined In the three cross-sectional studies by direct examination of fecal samples and modified Ritchie-Frick concentration method. Intestinal parasitism distribution was analysed and the trend during 1995-2005 described. The prevalence of intestinal parasitism in children aged less than 5 increased from 62,5 % in 1995 to 66,7 % in 2001 and to 69 % in 2005; soil-transmitted helminthiasis prevalence in this age group was 37,5 % in 1995, 23,6 % in 2001 and 27,6 % in 2005. The prevalence of intestinal parasitism for children aged over 5 increased from 86,2 % in 1995 to 89,1 % in 2005; soil-transmitted helminthiasis prevalence was 62,9 % in 1995, 39,8 % in 2001 and 23,9 % in 2005. Soil-transmitted helminthiasis was endemic and presented high prevalence during the study period. Effective control measures are needed to prevent intestinal parasitism in pre-school and schoolchildren.

  4. Cancer survival in Australia, Canada, Denmark, Norway, Sweden, and the UK, 1995–2007 (the International Cancer Benchmarking Partnership): an analysis of population-based cancer registry data

    Science.gov (United States)

    Coleman, MP; Forman, D; Bryant, H; Butler, J; Rachet, B; Maringe, C; Nur, U; Tracey, E; Coory, M; Hatcher, J; McGahan, CE; Turner, D; Marrett, L; Gjerstorff, ML; Johannesen, TB; Adolfsson, J; Lambe, M; Lawrence, G; Meechan, D; Morris, EJ; Middleton, R; Steward, J; Richards, MA

    2011-01-01

    Summary Background Cancer survival is a key measure of the effectiveness of health-care systems. Persistent regional and international differences in survival represent many avoidable deaths. Differences in survival have prompted or guided cancer control strategies. This is the first study in a programme to investigate international survival disparities, with the aim of informing health policy to raise standards and reduce inequalities in survival. Methods Data from population-based cancer registries in 12 jurisdictions in six countries were provided for 2·4 million adults diagnosed with primary colorectal, lung, breast (women), or ovarian cancer during 1995–2007, with follow-up to Dec 31, 2007. Data quality control and analyses were done centrally with a common protocol, overseen by external experts. We estimated 1-year and 5-year relative survival, constructing 252 complete life tables to control for background mortality by age, sex, and calendar year. We report age-specific and age-standardised relative survival at 1 and 5 years, and 5-year survival conditional on survival to the first anniversary of diagnosis. We also examined incidence and mortality trends during 1985–2005. Findings Relative survival improved during 1995–2007 for all four cancers in all jurisdictions. Survival was persistently higher in Australia, Canada, and Sweden, intermediate in Norway, and lower in Denmark, England, Northern Ireland, and Wales, particularly in the first year after diagnosis and for patients aged 65 years and older. International differences narrowed at all ages for breast cancer, from about 9% to 5% at 1 year and from about 14% to 8% at 5 years, but less or not at all for the other cancers. For colorectal cancer, the international range narrowed only for patients aged 65 years and older, by 2–6% at 1 year and by 2–3% at 5 years. Interpretation Up-to-date survival trends show increases but persistent differences between countries. Trends in cancer incidence and

  5. National Trends in Pediatricians' Practices and Attitudes About Breastfeeding: 1995 to 2014.

    Science.gov (United States)

    Feldman-Winter, Lori; Szucs, Kinga; Milano, Aubri; Gottschlich, Elizabeth; Sisk, Blake; Schanler, Richard J

    2017-10-01

    The American Academy of Pediatrics (AAP) has affirmed breastfeeding as the preferred method of infant feeding; however, there has been little systematic examination of how pediatricians' recommendations, affiliated hospitals' policies, counseling practices, and attitudes toward breastfeeding have shifted over the past 2 decades. These trends were examined from 1995 to 2014. Data are from the Periodic Survey (PS) of Fellows, a nationally representative survey of AAP members. PS #30 (1995; response rate = 72%; N = 832), PS #57 (2004; response rate = 55%; N = 675), and PS #89 (2014; response rate = 51%; N = 620) collected demographics, patient and practice characteristics, and detailed responses on pediatricians' recommendations, affiliated hospitals' policies, counseling practices, and attitudes toward breastfeeding. By using bivariate statistics and logistic regression models, the analysis investigated changes over time with predicted values (PVs). From 1995 to 2014, more pediatricians reported their affiliated hospitals applied for "baby-friendly" designation (PV = 12% in 1995, PV = 56% in 2014; P breastfeeding (65% to 76% [ P breastfeeding (PV = 70% in 1995, PV = 57% in 2014; P breastfeeding problems ( P AAP policy from 1995 to 2014; however, their attitudes about the likelihood of breastfeeding success have worsened. These 2 divergent trends indicate that even as breastfeeding rates continue to rise, continued efforts to enhance pediatricians' training and attitudes about breastfeeding are necessary. Copyright © 2017 by the American Academy of Pediatrics.

  6. Time trends of cancer mortality among elderly in Italy, 1970–2008: an observational study

    Directory of Open Access Journals (Sweden)

    Bidoli Ettore

    2012-10-01

    Full Text Available Abstract Background The aging of the Italian population will unavoidably lead to a growing number of persons diagnosed and living with cancer. A comprehensive description of the burden of cancer mortality among Italian elderly (65-84 years of age in the last four decades has not been carried out yet. Cancer mortality rates were used to describe time trends between 1970-2008. Methods Mortality counts, provided by the Italian National Institute of Statistics, were grouped according to data availability: in quinquennia from 1970-74 through 1995-99, and in 2000-03 and 2006-08 groups. Age-standardized rates (world population were computed by calendar periods while annual percent changes (APCs were computed for elderly and middle aged (35-64 years people for the period 1995-2008. Results The number of cancer deaths in elderly nearly doubled between 1970-74 (31,400 deaths/year in men, and 24,000 in women and 2006-08 (63,000 deaths/year in men, and 42,000 in women. Overall cancer mortality rates peaked during the quinquennia 1985-89 and 1990-94 (about 1,500/100,000 in men and 680 in women and declined thereafter. Throughout 1995-2008 cancer mortality rates decreased by -1.6%/year in men and -0.9%/year in women. These decreases were mainly driven by cancers of the stomach, bladder, prostate, and lung (APC = -3.3%, -2.7%, -2.5%, -2.2%, respectively in men, and by cancers of the stomach, bladder, and breast (APC = -3.5%, -1.9%, -1.1%, respectively in women. Conversely, increases in mortality rates between 1995 and 2008 were recorded for lung cancer (APC = +0.6% in women, cutaneous melanoma (APC = +1.7% in men, and pancreatic cancer (APC = +0.6% in men and +0.9% in women. Conclusions Overall favorable trends in cancer mortality were observed among Italian elderly between 1995 and 2008. Early diagnosis, improved efficacy of anti-cancer treatments and management of comorbidities are the most likely explanations of these positive

  7. Lung Cancer Trends

    Science.gov (United States)

    ... the Biggest Cancer Killer in Both Men and Women” Stay Informed Trends for Other Kinds of Cancer Breast Cervical Colorectal (Colon) Ovarian Prostate Skin Cancer Home Lung Cancer Trends Language: English Español (Spanish) Recommend ...

  8. Epidemiology of large intestinal cancer in Nagasaki city with reference to atomic bomb exposure, 1973∼1982

    International Nuclear Information System (INIS)

    Kinoshita, Shingo; Shimokawa, Isao; Iwasaki, Keisuke; Sakai, Hidetaka; Matsuo, Takeshi; Ikeda, Takayoshi; Mori, Hiroyuki; Mine, Mariko

    1988-01-01

    Epidemiological studies were conducted on 1098 cases of large intestinal cancer (615 cases of colon cancer and 483 cases of rectum cancer) registered at the Nagasaki Tumor Registry from 1973 to 1982, with emphasis on the relation to radiation exposure. The incidence in atomic bomb survivors was not significantly different from that in non-exposed persons, but the incidence in persons exposed at a young age tends to be higher, particularly the incidence of colon cancer in females. By site, about 56% of all colorectal cases investigated were shown to originate in the colon. In the colon, sigmoid cancer was the most frequent in both males and females, but there was no difference with regard to exposure status. In a comparison of the incidence during the first and second halves of the period examined, colorectal cancer revealed a general increasing trend, particularly for colon cancer in males and rectum cancer in females. Histologically, over 90% was differentiated adenocarcinoma and showed no difference by age, sex or exposure status. Nevertheless, it is noteworthy that musinous carcinoma was more frequent in atomic bomb survivors than in non-exposed people. Further analysis of the incidence, site and histologic type of colorectal cancer, especially in the group exposed at a young age, is necessary. (author)

  9. Water quality's determination at the Mino River during 1973-1995. Prediction analysis for 2010; Estudio de la calidad del agua del rio Mino durante el periodo 1973-1995. Analisis predictivo a 2010

    Energy Technology Data Exchange (ETDEWEB)

    De las Heras, A.; Medgar, M. J.

    2004-07-01

    The aim of the present work was to determine the water quality at the Mino river (Galicia), which belongs to the North river basin, as well as the problems associated to the contaminant contributions originated due to population changes, industrial development and agriculture and live-sock activities during a 23 years period (1973-1995). Similarly, the prediction of such changes till the year 2010 is also realized. The 26 analyzed parameters were obtained from the Database of the COCA-MOPU (Water Quality Control Web), and they were statistically analyzed by means of the hierarchical cluster analysis, principal complements multi variance analysis and the predictor technique for temporal series. Four different factors were identified: alkalinity, physical water characteristics, salinity and organic burden, with an accumulated variance of 60.2%. The predictive analysis adjusted to the ARIMA model, shows the tendency to rise of variables defining alkalinity, salinity and organic matter, if present conditions are maintained. (Author) 17 refs.

  10. Risk for Hospitalization With Depression After a Cancer Diagnosis: A Nationwide, Population-Based Study of Cancer Patients in Denmark From 1973 to 2003

    DEFF Research Database (Denmark)

    Dalton, S.O.; Laursen, T.M.; Nylandsted, Lone Ross

    2009-01-01

    for both men and women surviving hormone-related cancers, for women surviving smoking-related cancers, and for men surviving virus- and immune-related cancers. Conclusion This study confirms an increased risk for depression in patients facing a disruptive event like cancer. Early recognition and effective......Purpose As more people survive cancer, it is necessary to understand the long-term impact of cancer. We investigated whether cancer survivors are at increased risk for hospitalization for depression. Methods We linked data on all 5,703,754 persons living in Denmark on January 1, 1973, or born...... thereafter to the Danish Cancer Registry and identified 608,591 adults with a diagnosis of cancer. Follow-up for hospitalization for depression in the Danish Psychiatric Central Register from 1973 through 2003 yielded 121,227,396 person-years and 121,304 hospitalizations for depression. The relative risk (RR...

  11. Trends in colorectal cancer survival in northern Denmark: 1985-2004.

    Science.gov (United States)

    Iversen, L H; Nørgaard, M; Jepsen, P; Jacobsen, J; Christensen, M M; Gandrup, P; Madsen, M R; Laurberg, S; Wogelius, P; Sørensen, H T

    2007-03-01

    The prognosis for colorectal cancer (CRC) is less favourable in Denmark than in neighbouring countries. To improve cancer treatment in Denmark, a National Cancer Plan was proposed in 2000. We conducted this population-based study to monitor recent trends in CRC survival and mortality in four Danish counties. We used hospital discharge registry data for the period January 1985-March 2004 in the counties of north Jutland, Ringkjøbing, Viborg and Aarhus. We computed crude survival and used Cox proportional hazards regression analysis to compare mortality over time, adjusted for age and gender. A total of 19,515 CRC patients were identified and linked with the Central Office of Civil Registration to ascertain survival through January 2005. From 1985 to 2004, 1-year and 5-year survival improved both for patients with colon and rectal cancer. From 1995-1999 to 2000-2004, overall 1-year survival of 65% for colon cancer did not improve, and some age groups experienced a decreasing 1-year survival probability. For rectal cancer, overall 1-year survival increased from 71% in 1995-1999 to 74% in 2000-2004. Using 1985-1989 as reference period, 30-day mortality did not decrease after implementation of the National Cancer Plan in 2000, neither for patients with colon nor rectal cancer. However, 1-year mortality for patients with rectal cancer did decline after its implementation. Survival and mortality from colon and rectal cancer improved before the National Cancer Plan was proposed; after its implementation, however, improvement has been observed for rectal cancer only.

  12. Water vapour trends at several tropospheric levels over South America between 1973 and 2003

    International Nuclear Information System (INIS)

    Morales, L.; Mattar, C.; Da-Silva, L.; Abarca, R.

    2009-01-01

    In this paper water vapour trends were analyzed at several tropospheric levels over South America between 1973 and 2003. It was carried out using in situ values retrieved by 15 radiosonde stations and NCEP NCAR Reanalysis data (NNR). NNR and radiosonde water vapour data were linked to Koeppen-Geiger climatic zones to calculate anomalies, trends, and the non-parametric statistical significance for each mandatory level. A methodology used to process radiosonde data is shown. Water vapour trends in tropical climates presented positive decadal trends. This is statistically significant for the first mandatory levels retrieved by radiosonde. The highest values are presented in average with NNR; the decadal magnitude for climate Af being 0.15 g kg -1 for 1000 and 925 h Pa, and for climate As 0.27 g kg -1 for 925 and 850 h Pa. For non-tropical climates the magnitude trends of specific humidity are affected by the spatial resolution of NNR, which is seen when comparing the results received by the radiosondes. Finally, this paper shows the initial results of water vapour content trends in the last three decades over South America. Strong climatic events and synoptic oscillations were not commented upon.

  13. Trends in scientific activity addressing transmissible spongiform encephalopathies: a bibliometric study covering the period 1973–2002

    Directory of Open Access Journals (Sweden)

    Iribarren-Maestro Isabel

    2006-10-01

    Full Text Available Abstract Background The purpose of this study is to analyse the trends in scientific research on transmissible spongiform encephalopathies by applying bibliometric tools to the scientific literature published between 1973 and 2002. Methods The data for the study were obtained from Medline database, in order to determine the volume of scientific output in the above period, the countries involved, the type of document and the trends in the subject matters addressed. The period 1973–2002 was divided in three sub-periods. Results We observed a significant growth in scientific production. The percentage of increase is 871.7 from 1973 to 2002. This is more evident since 1991 and particularly in the 1996–2001 period. The countries found to have the highest output were the United States, the United Kingdom, Japan, France and Germany. The evolution in the subject matters was almost constant in the three sub-periods in which the study was divided. In the first and second sub-periods, the subject matters of greatest interest were more general, i.e Nervous system or Nervous system diseases, Creutzfeldt-Jakob disease, Scrapie, and Chemicals and Drugs, but in the last sub-period, some changes were observed because the Prion-related matters had the greatest presence. Collaboration among authors is small from 1973 to 1992, but increases notably in the third sub-period, and also the number of authors and clusters formed. Some of the authors, like Gajdusek or Prusiner, appear in the whole period. Conclusion The study reveals a very high increase in scientific production. It is related also with the beginnings of research on bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease, with the establishment of progressive collaboration relationships and a reflection of public health concerns about this problem.

  14. Birth order and risk of childhood cancer in the Danish birth cohort of 1973-2010.

    Science.gov (United States)

    Schüz, Joachim; Luta, George; Erdmann, Friederike; Ferro, Gilles; Bautz, Andrea; Simony, Sofie Bay; Dalton, Susanne Oksbjerg; Lightfoot, Tracy; Winther, Jeanette Falck

    2015-11-01

    Many studies have investigated the possible association between birth order and risk of childhood cancer, although the evidence to date has been inconsistent. Birth order has been used as a marker for various in utero or childhood exposures and is relatively straightforward to assess. Data were obtained on all children born in Denmark between 1973 and 2010, involving almost 2.5 million births and about 5,700 newly diagnosed childhood cancers before the age of 20 years. Data were analyzed using Poisson regression models. We failed to observe associations between birth order and risk of any childhood cancer subtype, including acute lymphoblastic leukemia; all rate ratios were close to one. Further analyses stratified by birth cohort (those born between 1973 and 1990, and those born between 1991 and 2010) also failed to show any associations. Considering stillbirths and/or controlling for birth weight and parental age in the analyses had no effect on the results. Analyses by years of birth (those born between 1973 and 1990, and those born between 1991 and 2010) did not show any changes in the overall pattern of no association. In this large cohort of all children born in Denmark over an almost 40-year period, we did not observe an association between birth order and the risk of childhood cancer.

  15. Development in incidence of breast cancer in non-screened Danish women, 1973-2002--a population-based study

    DEFF Research Database (Denmark)

    Fuglede, Niels; Langballe, Oline; Svendsen, Anne Louise

    2006-01-01

    The authors report on the incidence rates of breast cancer overall and by histology in a population of unscreened women constituting approximately 80% of the total population of women in Denmark from 1973-2002, utilizing the files of the nationwide Danish Cancer Registry. The age-specific incidence...... no disproportionate changes by histology in any age group from 1988-2002. Thus, previous reports of a disproportionate increase in lobular breast cancer could not be confirmed in a non-screened population, whereas important changes over the past decade in the age-specific incidence pattern of breast cancer particular...... rates of breast cancer increased throughout the period, and further, marked changes in the age-specific incidence pattern were observed, where the plateau and change of slope around the age of 46-48 in 1973-1981 shifted to around age 64-66 years in 1994-2002. Age-period-cohort modeling indicated...

  16. Trend analysis by a piecewise linear regression model applied to surface air temperatures in Southeastern Spain (1973–2014)

    OpenAIRE

    Campra, Pablo; Morales, Maria

    2016-01-01

    The magnitude of the trends of environmental and climatic changes is mostly derived from the slopes of the linear trends using ordinary least-square fitting. An alternative flexible fitting model, piecewise regression, has been applied here to surface air temperature records in southeastern Spain for the recent warming period (1973–2014) to gain accuracy in the description of the inner structure of change, dividing the time series into linear segments with different slopes. Breakpoint y...

  17. Trends in socioeconomic inequalities in cancer mortality in Barcelona: 1992–2003

    Directory of Open Access Journals (Sweden)

    Pasarín M Isabel

    2009-01-01

    Full Text Available Abstract Background The objective of this study was to assess trends in cancer mortality by educational level in Barcelona from 1992 to 2003. Methods The study population comprised Barcelona inhabitants aged 20 years or older. Data on cancer deaths were supplied by the system of information on mortality. Educational level was obtained from the municipal census. Age-standardized rates by educational level were calculated. We also fitted Poisson regression models to estimate the relative index of inequality (RII and the Slope Index of Inequalities (SII. All were calculated for each sex and period (1992–1994, 1995–1997, 1998–2000, and 2001–2003. Results Cancer mortality was higher in men and women with lower educational level throughout the study period. Less-schooled men had higher mortality by stomach, mouth and pharynx, oesophagus, larynx and lung cancer. In women, there were educational inequalities for cervix uteri, liver and colon cancer. Inequalities of overall and specific types of cancer mortality remained stable in Barcelona; although a slight reduction was observed for some cancers. Conclusion This study has identified those cancer types presenting the greatest inequalities between men and women in recent years and shown that in Barcelona there is a stable trend in inequalities in the burden of cancer.

  18. Survival trends of US dialysis patients with heart failure: 1995 to 2005.

    LENUS (Irish Health Repository)

    Stack, Austin G

    2012-01-31

    BACKGROUND AND OBJECTIVES: Congestive heart failure (CHF) is a major risk factor for death in end-stage kidney disease; however, data on prevalence and survival trends are limited. The objective of this study was to determine the prevalence and mortality effect of CHF in successive incident dialysis cohorts. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This was a population-based cohort of incident US dialysis patients (n = 926,298) from 1995 to 2005. Age- and gender-specific prevalence of CHF was determined by incident year, whereas temporal trends in mortality were compared using multivariable Cox regression. RESULTS: The prevalence of CHF was significantly higher in women than men and in older than younger patients, but it did not change over time in men (range 28% to 33%) or women (range 33% to 36%). From 1995 to 2005, incident death rates decreased for younger men (<\\/=70 years) and increased for older men (>70 years). For women, the pattern was similar but less impressive. During this period, the adjusted mortality risks (relative risk [RR]) from CHF decreased in men (from RR = 1.06 95% Confidence intervals (CI) 1.02-1.11 in 1995 to 0.91 95% CI 0.87-0.96 in 2005) and women (from RR = 1.06 95% CI 1.01-1.10 in 1995 to 0.90 95% CI 0.85-0.95 in 2005 compared with referent year 2000; RR = 1.00). The reduction in mortality over time was greater for younger than older patients (20% to 30% versus 5% to 10% decrease per decade). CONCLUSIONS: Although CHF remains a common condition at dialysis initiation, mortality risks in US patients have declined from 1995 to 2005.

  19. Prevalence and trend of COPD from 1995-1997 to 2006-2008: The HUNT study, Norway.

    Science.gov (United States)

    Bhatta, Laxmi; Leivseth, Linda; Mai, Xiao-Mei; Chen, Yue; Henriksen, Anne Hildur; Langhammer, Arnulf; Brumpton, Ben Michael

    2018-05-01

    COPD is a major cause of morbidity and mortality across the world and new estimates of prevalence and trend are of great importance. We aimed to estimate the prevalence and trend of COPD from 1995-1997 to 2006-2008 in Norwegian adults ≥40 years from the Nord-Trøndelag Health Study. COPD was assessed using a fixed-ratio and lower limit of normal (LLN) criteria. Pre-bronchodilator spirometry was performed during 1995-1997 (n = 7158) and 2006-2008 (n = 8788). The prevalence of COPD was weighted using the inverse probability of selection and predicted probability of response. The prevalence of pre-bronchodilator COPD was 16.7% in 1995-1997 and 14.8% in 2006-2008 using fixed-ratio criteria, and 10.4% in 1995-1997 and 7.3% in 2006-2008 using LLN criteria. The prevalence of LLN COPD was higher among men (13.0% in 1995-1997, 7.7% in 2006-2008) than women (8.0% in 1995-1997, 6.9% in 2006-2008). From 1995-1997 to 2006-2008, the prevalence decreased among men but remained relatively stable among women. Over the 11-year period, the cumulative incidence of pre-bronchodilator COPD using LLN criteria was 3.3% and 2.7% among men and women respectively. The prevalence of self-reported asthma and respiratory symptoms increased. The prevalence declined in men but not in women from 1995-1997 to 2006-2008, and was consistently higher among men than women. Copyright © 2018 Elsevier Ltd. All rights reserved.

  20. Trends in radiology in Finland between 1995 and 2000

    International Nuclear Information System (INIS)

    Hakanen, Arvi; Jaervinen, Hannu; Soimakallio, Seppo

    2003-01-01

    The aim of this study was to demonstrate the applicability of a joint nomenclature, i.e., the examination coding system used in Finland, for making a nationwide summary of the radiological examinations and interventional procedures. Another objective was to find trends in radiological practices in Finland between 1995 and 2000 by comparing the nationwide summaries made by Radiation and Nuclear Safety Authority (STUK). An inquiry for the numbers of radiological examinations performed in 2000 was sent to 473 medical radiation users, i.e., safety license holders obtained from the registry maintained by STUK. In 2000, the proportions of plain radiography, contrast-enhanced radiography, angiography, computed tomography and radiological interventional procedures were approximately 91.1, 1.4, 0.9, 5.0, and 1.5%, respectively (distribution of medical examinations). Between 1995 and 2000, the number of medical X-ray examinations showed a slight decrease from ca. 4.2 million to ca. 4.1 million. During the investigated five years period the frequency of contrast enhanced radiography diminished ca. 50% while the frequency of computed tomography increased ca. 20%. The reported number of ultrasonographic examinations showed a slight increase to approximately 0.5 million, whereas the reported number of MRI examinations increased approximately twofold to approximately 0.1 million. The observed trends in radiological practices are useful in attempts to optimize the resources of STUK in the field of radiological protection. (orig.)

  1. Improvements in breast cancer survival between 1995 and 2012 in Denmark

    DEFF Research Database (Denmark)

    Jensen, Maj-Britt; Ejlertsen, Bent; Mouridsen, Henning T

    2016-01-01

    Background Breast cancer mortality has declined from 1995 through 2012 which may be attributed to earlier diagnosis, changes in lifestyle risk factors, and improved treatments. To a large extent the relative contribution of these modalities are unknown. Mammography screening was introduced late...... was extended considerable. Methods A population-based study of 68 842 breast cancer patients registered in the clinical database of the Danish Breast Cancer Cooperative Group in 1995-2012. Comprehensive data on prognostic factors, comorbidity and treatment together with complete follow-up for survival were...... in Denmark; in 1995 around 20% of the Danish female population aged 50-69 was covered by population-based screening, and this was in 2008 extended to the entire population. Breast conserving surgery gradually replaced mastectomy, and sentinel node biopsy was introduced. In the same period adjuvant treatment...

  2. Annual Trends of Gastrointestinal Cancers Mortality in Iran During 1990-2015; NASBOD Study.

    Science.gov (United States)

    Salimzadeh, Hamideh; Delavari, Farnaz; Sauvaget, Catherine; Rezaee, Negar; Delavari, Alireza; Kompani, Farzad; Rezaei, Nazila; Sheidaei, Ali; Modirian, Mitra; Haghshenas, Rosa; Chegini, Maryam; Gohari, Kimiya; Zokaiee, Hossein; Farzadfar, Farshad; Malekzadeh, Reza

    2018-02-01

    Gastrointestinal (GI) neoplasms are among the most common cancers in Iran. This study aimed to measure annual trends in mortality rates from GI cancers in Iran between 1990 and 2015. This study was part of an ongoing study termed the 'National and Subnational Burden of Diseases' study in Iran. Data used in this study was obtained from the Iranian Death Registration System (1995 to 2010) and from 2 major cemeteries in Tehran (1995 to 2010) and Isfahan (2007 to 2010). All-cause mortality rates were estimated using the spatio-temporal model and the Gaussian process regression model. Age-standardized mortality rates (ASMR) per 100 000 person-years was calculated using data from Iran and the standard world population for comparison. Among GI cancers, gastric cancer represented the leading cause of mortality followed by cancers of the esophagus, liver, and colorectal cancers with the ASMR of 20.5, 5.8, 4.4, and 4.0 per 100 000 persons-years, respectively, between 1990 and 2015. While a decreasing trend occurred in mortality of esophageal, gastric, and colorectal cancers, particularly in the recent decade, we recorded an upward pattern and steady rise in mortality rates from liver, pancreatic, and gallbladder cancers during the study period. The ASMR of all studied causes were enhanced by advancing age and were found to be more prominent in adults aged 50 or older. Among all age-groups, higher death rates were detected in males versus females for all studied cancers except for gallbladder and biliary tract cancers. Gastric cancer mortality is still high and death rates from several other GI cancers are increasing in the nation. Interventions for cancer prevention, early detection, and access to high quality cancer treatment services are needed to reduce GI cancer burden and death rates in Iran and in the region. © 2018 The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution License (http

  3. Trends in the prevalence of elevated skinfold thickness among children and adolescents in Shandong Province, China, 1995-2014.

    Science.gov (United States)

    Wang, Shu-Rong; Cheng, Yan; Chen, Min; Zhang, Ying-Xiu

    2018-04-04

    There are abundant data on secular trends in BMI; however, information on the change in subcutaneous fat is limited. The present study examined the trends in the prevalence of elevated skinfold thickness among children and adolescents over the past 19 years (1995-2014) in Shandong Province, China. Data for the study were obtained from two cross-sectional surveys of schoolchildren carried out in 1995 and 2014. Triceps and subscapular skinfold thicknesses (SFT) of all participants were measured. The sum of triceps and subscapular SFT (SSFT) was applied. Children and adolescents with SSFT above or equal to the national age- and sex-specific 85th percentile were defined as 'high SFT'. Shandong Province, China. A total of 16 917 students aged 7-18 years were included. For both boys and girls, an increasing trend in 'high SFT' was observed between 1995 and 2014. The overall prevalence of 'high SFT' increased from 10·31 % for boys and 13·40 % for girls in 1995 to 33·94 % for boys and 29·30 % for girls in 2014 (P<0·01). There are more children and adolescents with very high levels of SFT. These trends describe very unfavourable changes in the body composition and should give cause for concern.

  4. Rural-Urban Differences in Cancer Incidence and Trends in the United States.

    Science.gov (United States)

    Zahnd, Whitney E; James, Aimee S; Jenkins, Wiley D; Izadi, Sonya R; Fogleman, Amanda J; Steward, David E; Colditz, Graham A; Brard, Laurent

    2017-07-27

    Cancer incidence and mortality rates in the US are declining, but this decrease may not be observed in rural areas where residents are more likely to live in poverty, smoke, and forego cancer screening. However, there is limited research exploring national rural-urban differences in cancer incidence and trends. We analyzed data from the North American Association of Central Cancer Registries' public use dataset, which includes population-based cancer incidence data from 46 states. We calculated age-adjusted incidence rates, rate ratios, and annual percentage change (APC) for: all cancers combined; selected individual cancers; and cancers associated with tobacco use and human papillomavirus (HPV). Rural-urban comparisons were made by demographic, geographic, and socioeconomic characteristics for 2009 to 2013. Trends were analyzed for 1995 to 2013. Combined cancers incidence rates were generally higher in urban populations, except for the South, though the urban decline in incidence rate was greater than in rural populations (10.2% vs. 4.8%, respectively). Rural cancer disparities included higher rates of tobacco associated, HPV associated, lung and bronchus, cervical , and colorectal cancers across most population groups. Further, HPV-associated cancer incidence rates increased in rural areas (APC=0.724, purban areas. Cancer rates associated with modifiable risks - tobacco, HPV, and some preventive screening modalities (e.g. colorectal and cervical cancers) - were higher in rural compared to urban populations. Population-based, clinical, and/or policy strategies and interventions that address these modifiable risk factors could help reduce cancer disparities experienced in rural populations. Copyright ©2017, American Association for Cancer Research.

  5. Spatial Analysis of Regional Factors and Lung Cancer Mortality in China, 1973-2013.

    Science.gov (United States)

    Shen, Xiaoping; Wang, Limin; Zhu, Li

    2017-04-01

    Background: China's lung cancer crude death rate has increased 6.9-fold from 1973 to 2014. During this time, the country experienced extremely rapid economic growth and social change. It is important to understand the effects of risk factors on lung cancer mortality (LCM) for better allocation of limited resources of cancer prevention and control in China. Methods: Using three nationwide mortality surveys from 1973 to 2005, Global Health Data Exchange data in 2013, three nationwide smoking surveys from 1984 to 2013, four population censuses from 1964 to 2000, and other datasets, we have compiled datasets and developed spatial random effect models to assess the association of various area-level-contributing factors on LCM. Spatial scan statistics are used to detect high-risk clusters of LCM. Results: LCM is higher in urban and more industrialized areas (RR = 1.17) compared with those in rural areas. The level of industrial development's effect is higher for men, which accounts for about 70% of all LCM. Smoking is positively associated with regional variation of LCM rates, and the effect is higher for women than for men. Conclusions: The geographic pattern of high LCM in China is different from that of Western countries. LCM is positively associated with higher socioeconomic status, with more urbanized areas at a higher level of industrial development. Impact: There is a need to further explore additional risk in the high-risk clusters. The study is about China, but this situation may happen in other countries experiencing rapid industrialization and other developing countries. Cancer Epidemiol Biomarkers Prev; 26(4); 569-77. ©2017 AACR See all the articles in this CEBP Focus section, "Geospatial Approaches to Cancer Control and Population Sciences." ©2017 American Association for Cancer Research.

  6. Trends in hormone use and ovarian cancer incidence in US white and Australian women: implications for the future.

    Science.gov (United States)

    Webb, Penelope M; Green, Adèle C; Jordan, Susan J

    2017-05-01

    To compare trends in ovarian cancer incidence in the USA and Australia in relation to changes in oral contraceptive pill (OCP) and menopausal hormone therapy (MHT) use. US cancer incidence data (1973-2013) were accessed via SEER*Stat; Australian data (1982-2012) were accessed from the Australian Institute of Health and Welfare Cancer Incidence and Mortality books. Age-period-cohort models were constructed to assess trends in ovarian cancer incidence by birth cohort and year of diagnosis. Ovarian cancer rates were increasing until the cohorts born around 1918 in the USA and 1923 in Australia who were the first to use the OCP. They then declined dramatically across subsequent cohorts such that rates for the 1968 cohort were about half those of women born 45 years earlier; however, there are early suggestions that this decline may not continue in more recent cohorts. In contrast, despite the large reduction in MHT use, there was no convincing evidence that ovarian cancer incidence rates in either country were lower after 2002 than would have been expected based on the declining trend from 1985. The major driver of ovarian cancer incidence rates appears to be the OCP. This means that when those women born since the late 1960s (who have used the OCP at high rates from an early age) reach their 60s and 70s, incidence rates are likely to stop falling and may even increase with changes in the prevalence of other factors such as tubal ligation and obesity. Forward predictions based on past trends may thus underestimate future rates and numbers of women likely to be affected.

  7. Cancer incidence patterns among children and adolescents in Taiwan from 1995 to 2009: a population-based study.

    Science.gov (United States)

    Hung, Giun-Yi; Horng, Jiun-Lin; Lee, Yu-Sheng; Yen, Hsiu-Ju; Chen, Chao-Chun; Lee, Chih-Ying

    2014-11-15

    Currently, little information is available on childhood cancer incidence rates in Eastern Asia. The objective of this study was to report the first population-based cancer surveillance of children and adolescents in Taiwan. Data from the Taiwan Cancer Registry were examined for cancer frequencies and incidence rates among individuals ages birth to 19 years from 1995 to 2009. Types of cancers were grouped according to the International Classification of Childhood Cancer. Rates were compared by sex and age. For further comparisons with other countries, rates were age standardized to the 2000 world standard population in 5-year age groups. Trends in incidence rates also were evaluated. In total, 12,315 individuals were diagnosed with childhood cancers, for an age-standardized incidence rate (ASR) of 132.1 per million person-years from 1995 to 2009. The male-to-female incidence rate ratio was 1.19. Overall, leukemias were the most common cancer (ASR, 39.1 per million person-years), followed by central nervous system neoplasms (15.8 per million person-years), and lymphomas (15.3 per million person-years). During the 15-year study period, the incidence rates increased by 1% annually. Compared with other countries, the rate of hepatic tumors was 2 times greater in Taiwan. The rate of germ cell neoplasms in Taiwan was similar to that in the United States and was 1.3 to 1.9 times greater compared with Canada, Brazil, Israel, and Japan. Based on the current data, the observed increase in overall incidence rates was attributable only marginally to improvements in case ascertainment and diagnostic procedures. The high rates of malignant hepatic tumors and germ cell neoplasms in Taiwan suggest variations in the background risk factors. © 2014 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society.

  8. Trends in Disability-Free Life Expectancy in Japan, 1995–2004

    OpenAIRE

    Hashimoto, Shuji; Kawado, Miyuki; Seko, Rumi; Murakami, Yoshitaka; Hayashi, Masayuki; Kato, Masahiro; Noda, Tatsuya; Ojima, Toshiyuki; Nagai, Masato; Tsuji, Ichiro

    2010-01-01

    Background In Japan, life expectancy at birth is currently the highest in the world. However, recent trends in disability-free life expectancy in Japan have not been examined. Methods We used data from Japanese national surveys for the period 1995–2004. These surveys included information on activity status measured by common self-reported instruments. The numbers of expected years with and without activity limitation were estimated by using the Sullivan method. Results The numbers of expected...

  9. Cancer incidence of A-bomb survivors in Nagasaki City, 1973 - 1982

    International Nuclear Information System (INIS)

    Ikeda, Takayoshi; Shimokawa, Isao; Iwasaki, Keisuke; Matsuo, Takeshi; Mori, Hiroyuki; Mine, Mariko

    1988-01-01

    Subjects were residents older than 30 years ascertained through the population-based cancer registry in Nagasaki City during a ten-year period from 1973 to 1982. The total number of cancer patients was 6,243 (3,456 men and 2,787 women), 2,626 of whom were A-bomb survivors. Stomach cancer was the most common, irrespective of sex, in both exposed and non-exposed groups. Crude incidence of cancer of any organ was higher in the exposed group, especially the group of people entering the city early after the bombing, than the non-exposed group. In the groups exposed at <2,000 m and at 2,000 - 10,000 m from the hypocenter, the incidence of stomach, lung, and thyroid cancers and malignant lymphoma; and the incidence of stomach, breast, and thyroid cancers were radiation-dose dependent in men and women, respectively. Age-adjusted relative risks of breast and thyroid cancers were significantly higher in the exposed group of women than the non-exposed group. Comparing cancer incidence during the first and latter five years, the incidence of thyroid cancer and malignant lymphoma tended to decrease or remain unchanged in both men and women. The incidence of colorectal cancer showed a tendency to increase. An increased incidence of stomach and lung cancers was restricted to the exposed group of women. As for breast cancer, the exposed group of women had a tendency for decrease, as opposed to the non-exposed group with the increased incidence. There was no significant difference in histologic types between the exposed and non-exposed groups. (Namekawa, K.)

  10. An Online Atlas for Exploring Spatio-Temporal Patterns of Cancer Mortality (1972-2011) and Incidence (1995-2008) in Taiwan.

    Science.gov (United States)

    Ku, Wen-Yuan; Liaw, Yung-Po; Huang, Jing-Yang; Nfor, Oswald Ndi; Hsu, Shu-Yi; Ko, Pei-Chieh; Lee, Wen-Chung; Chen, Chien-Jen

    2016-05-01

    Public health mapping and Geographical Information Systems (GIS) are already being used to locate the geographical spread of diseases. This study describes the construction of an easy-to-use online atlas of cancer mortality (1972-2011) and incidence (1995-2008) in Taiwan.Two sets of color maps were made based on "age-adjusted mortality by rate" and "age-adjusted mortality by rank." AJAX (Asynchronous JavaScript and XML), JSON (JavaScript Object Notation), and SVG (Scaling Vector Graphic) were used to create the online atlas. Spatio-temporal patterns of cancer mortality and incidence in Taiwan over the period from 1972 to 2011 and from 1995 to 2008.The constructed online atlas contains information on cancer mortality and incidence (http://taiwancancermap.csmu-liawyp.tw/). The common GIS functions include zoom and pan and identity tools. Users can easily customize the maps to explore the spatio-temporal trends of cancer mortality and incidence using different devices (such as personal computers, mobile phone, or pad). This study suggests an easy- to-use, low-cost, and independent platform for exploring cancer incidence and mortality. It is expected to serve as a reference tool for cancer prevention and risk assessment.This online atlas is a cheap and fast tool that integrates various cancer maps. Therefore, it can serve as a powerful tool that allows users to examine and compare spatio-temporal patterns of various maps. Furthermore, it is an-easy-to use tool for updating data and assessing risk factors of cancer in Taiwan.

  11. Racial and Ethnic Disparities in the Incidence and Trends of Soft Tissue Sarcoma Among Adolescents and Young Adults in the United States, 1995-2008.

    Science.gov (United States)

    Hsieh, Mei-Chin; Wu, Xiao-Cheng; Andrews, Patricia A; Chen, Vivien W

    2013-09-01

    The aim of this study was to examine racial/ethnic disparities in the incidence rates and trends of soft tissue sarcoma (STS) by gender, age, and histological type among adolescents and young adults (AYAs) aged 15-29 years. The 1995-2008 incidence data from 25 population-based cancer registries, covering 64% of the United States population, were obtained from the North American Association of Central Cancer Registries. The Surveillance, Epidemiology and End Results AYA site recode and International Classification of Diseases for Oncology, 3rd Edition, were adopted to categorize STS histological types and anatomic groups. Age-adjusted incidence rates and average annual percent change (AAPC) were calculated. The incidence of all STSs combined was 34% higher in males than females (95% CI: 1.28, 1.39), 60% higher among blacks than whites (95% CI: 1.52, 1.68), and slightly higher among Hispanics than whites. Compared with whites, blacks had significantly higher incidence of fibromatous neoplasms, and Hispanics had significantly higher incidence of liposarcoma. Whites were more likely to be diagnosed with synovial sarcoma than blacks. Black and Hispanic males had significantly higher Kaposi sarcoma incidence than white males. The AAPC of all STSs combined showed a significant decrease from 1995 to 2008 (AAPC=-2.1%; 95% CI: -3.2%, -1.0%). However, after excluding Kaposi sarcoma, there was no significant trend. The incidence rates of STS histological types in AYAs vary among racial/ethnic groups. The declining trends of STS are due mainly to decreasing incidence of Kaposi sarcoma in all races/ethnicities. Research to identify factors associated with racial/ethnic disparities in AYA STS is necessary.

  12. Sex disparities in cancer incidence in Jiashan County, China, 1995-2014.

    Science.gov (United States)

    Jiang, Xiyi; Cai, Shaofang; Hu, Yunqing; Ye, Ding; Li, Qilong; Chen, Kun; Jin, Mingjuan

    2017-10-01

    To describe the sex-specific incidence rates and the male-to-female incidence-rate ratios (IRRs) of different cancer types, and to explore the corresponding sex disparities in an area of Eastern China. We used data from the Cancer Registry in Jiashan County, and calculated the sex-specific age-standardized (2010 China standard population) incidence rates and the male-to-female IRRs for different cancer types during the period 1995-2014. The age-standardized incidence rates of all cancers for the whole period 1995-2014 were 151.48 per 100,000 person-years for males and 83.75 per 100,000 person-years for females, and the corresponding male-to-female IRR was 1.81 (95% confidence interval: 1.77-1.85). Specifically, males presented higher incidences in most types of cancer with the exceptions of cancers of connective and other soft tissues, gallbladder (including extrahepatic bile ducts), and thyroid gland. In addition, the age-specific incidences of the ten most common cancers in males were higher than those in females in most age groups. Our results reveal a male predominance in incidence for a majority of cancers in Jiashan County, Eastern China. Possible explanations for these sex disparities in cancer incidence may include lifestyle factors, particularly smoking. Copyright © 2017. Published by Elsevier Ltd.

  13. [The trend in pregnancies terminated by a cesarean operation in Mexico during 1991-1995].

    Science.gov (United States)

    Juárez Ocaña, S J; Fajardo Gutiérrez, A; Pérez Palacios, G; Guerrero Morales, R G; Gómez Delgado, A

    1999-07-01

    In the last decades has been a worldwide trend to increase the number of cesarean sections as an alternative of obstetric resolution, phenomenon for which it was proposed a variety of explanation, this fact remains practically unknown in the institutions of the National Health System (NHS) in Mexico. To identify the trend of the pregnancy to end for cesarean sections during the years of 1991-1995 in the 32 states of de country, as well as of all the institutions of the National Health System. Descriptive, cross sectional and retrospective. We use the data of the Bureau of Statistics and Informatics of de Health Ministry of each one of the 32 states of the country, of the years 1991 to 1995, and of the number of cesarean sections made in the hospitals of the different institutions of the NHS. We started off with a data-base, to calculate frequency tables, and the specific rate of the cesarean section for each year, for each one of the states and institutions of the NHS. We calculate the secular trends using the annual rates of cesarean section, for each one of the states and institutions of the NHS. We also made bivariate analysis and estimated the odds ratio (OR) and 95% Confidence Interval (95% IC); and the statistic X2 for trend, setting the two tailed statistic significance level of 0.05. During the study period, there was 7,503,817 births in all hospitals of the NHS, of these births 1,929,865 (25.72%) was resolved by cesarean section. For the whole period it there was a clear trend to increment of the cesarean section, the rate for 1991 was 20.44%, and by 1995 was 28.58%, the raise for the period was 39.82%, with values of the OR for trend of 1.56; 95% IC (1.55-1.57). "P" SOLIDARIDAD and 21.7% for the Health Ministry, all trends were statistically significant. In relation to the institutes attending closed population the raise was of 53.27% [OR trend 1.82; 95% IC (1.81-1.83), "p" < 0.05], with the highest rate for the National Defense Ministry which had a rate

  14. Analysis of European ozone trends in the period 1995-2014

    Science.gov (United States)

    Yan, Yingying; Pozzer, Andrea; Ojha, Narendra; Lin, Jintai; Lelieveld, Jos

    2018-04-01

    Surface-based measurements from the EMEP and Airbase networks are used to estimate the changes in surface ozone levels during the 1995-2014 period over Europe. We find significant ozone enhancements (0.20-0.59 µg m-3 yr-1 for the annual means; P-value climate model EMAC, the importance of anthropogenic emissions changes in determining these changes over background sites are investigated. The EMAC model is found to successfully capture the observed temporal variability in mean ozone concentrations, as well as the contrast in the trends of 95th and 5th percentile ozone over Europe. Sensitivity simulations and statistical analysis show that a decrease in European anthropogenic emissions had contrasting effects on surface ozone trends between the 95th and 5th percentile levels and that background ozone levels have been influenced by hemispheric transport, while climate variability generally regulated the inter-annual variations of surface ozone in Europe.

  15. Prostate Cancer Treatment | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  16. Prostate Cancer Screening | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  17. Bladder Cancer Treatment | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  18. Kidney Cancer Treatment | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  19. Colorectal Cancer Treatment | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  20. Colorectal Cancer Screening | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  1. Cervical Cancer Screening | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  2. Recent trends in cancer mortality in Uruguay

    International Nuclear Information System (INIS)

    Garau, M.; Alonso, R.; Musetti, C.; Barrios, E.

    2010-01-01

    Objective: To analyze trends in cancer mortality in Uruguay in the period 1989-2008. Methodology: The National Cancer Registry (NCR) collects information from cancer mortality from the death certificates: 147 631 deaths were identified in the period from cancer, which was recorded topography, sex and age. They were calculated for each year mortality rates adjusted for age (TMAE) using as standard the world population. Trends were assessed using the method and calculated the joinpoint Estimated Annual Percent Change (ESPP). Results: The TMAE presents downward trend in both sexes (ESPP = significant -0.60 in men and -0.49 In women). In the period studied, mortality presented decreasing trend when it comes to cancer breast cancer in women (ESPP -0.79, significant), and increased for prostate cancer (ESPP = 0.70) and kidney (ESPP = 1.82 and 1.71 in men and women respectively). As regards the digestive system decreased mortality observed for esophageal cancer (ESPP in = -1.93 men and women = -1.78) and stomach (ESPP = -2.22 men and women -2.24 ). Mortality for cancer of colorectum is stable in men (ESPP = 0.35 No significant (NS)) and shows a decline slight but steady in women (ESPP -0.5). As for cancers that show strong association with smoking, decreased mortality observed lung and laryngeal cancer in men (ESPP = -1.11 and -2.05 respectively), confirming the trend found between 1990 and 2001; in women there is increased mortality from lung cancer (ESPP = 2.76) that is not accompanied by increased mortality from laryngeal cancer (-0.1 ESPP = NS). Mortality from cancers oral cavity and pharynx is stable, but in women a significant increase (ESPP = 1.84) is observed when the oral cavity is analyzed in isolation (lip, tongue, gums, palate). As cervical cancer, mortality trends in 20 years is to increase (ESPP = 1.14), however, if consider only the past decade, mortality appears stabilized (ESPP = 0.57 NS). Conclusions: The overall trend of cancer mortality (all sites

  3. Trends in fatal snakebites in Venezuela, 1995-2002.

    Science.gov (United States)

    Benítez, Jesús A; Rifakis, Pedro M; Vargas, Jair A; Cabaniel, Gilberto; Rodríguez-Morales, Alfonso J

    2007-01-01

    There have been few studies evaluating snakebite mortality in Venezuela and South America. In this study we evaluate trends in fatal snakebites occurring in Venezuela between 1995 and 2002. Epidemiological data for this study were retrieved from the records of the Ministry of Health of Venezuela. Using these data, we analyzed the impact of snakebites in Venezuela during the study period. During the study period, there were 266 reports of death due to snakebite; 79.7% were males, and 20.3% were females (P Mortality rate by age showed an age-dependent rate, with higher rates in older ages (P = .038). Snake envenomations are an important cause of injury and deaths in Venezuela as in many American countries. Surveillance of envenomations is essential for establishing guidelines, planning therapeutic supplies, and training medical staff on snakebite treatment, as well as assessing risk zones for travelers.

  4. Trends in doctor consultations, antibiotic prescription, and specialist referrals for otitis media in children : 1995-2003

    NARCIS (Netherlands)

    Plasschaert, Astrid I O; Rovers, Maroeska M; Schilder, Anne G M; Verheij, Theo J M; Hak, Eelko

    BACKGROUND: Reported trends regarding the incidence of otitis media and antibiotic prescription rates are inconsistent. OBJECTIVE: Our goal was to assess changes in incidence of consultation rates, antibiotic prescription, and referral rates for otitis media in children over the years 1995-2003.

  5. Analysis of data (1987-1995) from investigation of cancer mortality in high background radiation area of Yangjiang, China

    International Nuclear Information System (INIS)

    Tao Zufan; Akiba, S.; Zha Yongru

    1999-01-01

    homogeneity tests of RRs for all cancers and for site-specific cancer among the three dose groups in HBRA revealed that the RRs among the dose groups were not different statistically (P>0.05 for all). The results of RR estimation based on the combined data of 1979-1995, which included 125079 subjects, and total deaths of 10415 and cancer deaths of 1003 among 1698350 Pyr at risk, were generally consistent with those based on the data of 1987-1995 mentioned above. The RR (95% CI) for all cancers of whole HbRA was 0.99 (0.87-1.14) and the ERR (95% CI)/Sv of all cancers for both sexes and all ages was-0.10 (-0.67, 0.69) resulting from the combined data. Conclusion: The results from data of different periods demonstrated that an increased cancer risk associated with the high levels of natural radiation in HBRA was not found; on the contrary, there was a trend that the mortality of all cancers in HBRA was generally lower than that in CA, but not significantly different statistically

  6. Italian cancer figures, report 2009: Cancer trend (1998-2005).

    Science.gov (United States)

    2009-01-01

    the aim of this collaborative project of the Italian Network of Cancer Registries (Airtum; www.registri-tumori.it) was to analyse cancer incidence and mortality trends in Italy with special reference to the period 1998-2005. the study was based on the Airtum database, which collects and checks data from all the Airtum registries. The present study was based on 20 general and 2 specific populationbased cancer registries. Overall, we analysed 818,017 incident cases and 342,444 cancer deaths for the time period 1998-2005. Seventy percent of the analysed population was from the North of Italy, 17% from the Centre, and 13% from the South. A joinpoint analysis was carried out to detect the point in time where the trend changed; trends are described by means of the estimated annual percent change (APC), with appropriate 95% confidence intervals. Crude and standardized incidence and mortality rates were computed for 36 cancer sites, for both sexes, three age-classes (0-49, 50-69 and 70+ years), and three geographic areas (North, Centre, and South of Italy). Specific chapters are devoted to long-term trends (1986-2005), differences among age-groups, and international comparisons. In 1998-2005, cancer mortality for all sites showed a statistically significant decrease among men (APC - 1.7) and women (- 0.8). Mortality significantly decreased in both sexes for stomach cancer, rectum cancer, liver cancer, and Hodgkin lymphoma. Mortality also decreased among men for cancers of the upper aerodigestive tract, oesophagus, lung, prostate, urinary bladder, and leukaemia. Among women mortality decreased for cancers of the colon, bone, breast, and uterus not otherwise specified. An increase in mortality was recorded for lung cancer among women (+1.5) and melanoma among men (+2.6). Incidence for all cancers together (except non-melanoma skin cancers) increased among men (APC +0.3) and remained stable among women. Cancer sites which showed increasing incidence were thyroid and melanoma

  7. Long-term atmospheric visibility trend in Southeast China, 1973-2010

    Science.gov (United States)

    Deng, Junjun; Du, Ke; Wang, Kai; Yuan, Chung-Shin; Zhao, Juanjuan

    2012-11-01

    Particulate matter (PM) pollution in Southeast China has been worsening because of the rapid industrial development and urbanization, which have significant negative effects on atmospheric visibility. Characterization of the trend in atmospheric visibility is important for evaluating the impact of PM pollution on the impairment of visual air quality in urban and rural areas. Long-term trend in atmospheric visibility in Southeast China was analyzed for the period of 1973-2010 based on the meteorological data from the National Climatic Data Center (NCDC) database using four statistical methods: annual mean visibility, percentages of “very good” visibility and “bad” visibility, ridit analysis, and cumulative percentiles. The relationship of atmospheric extinction with Air Pollution Index (API) was studied. In addition, the effects of recent environment policies on visibility were studied. The results showed that the visibility had decreased in 94% stations of this region and prefecture stations had the highest decreasing trend of -3.1 km/decade during the entire period. The average visibility of all the 17 stations (i.e., region-average) declined at a rate of -2.0 km/decade, with a 38-year average of 18.1 km. Decrease in the percentage of “very good” visibility and increase in the percentage of “bad” visibility existed in 14 and 16 stations, respectively. Region-average percentage of “bad” visibility was in the range of 2.2-21.5%, with an increasing rate of 5.0% per decade, and that of “very good” visibility was 24.4-71.8%, with a decreasing rate of -10.7% per decade. During the entire period, county and prefecture stations had similar changing patterns and trends in visibility, while town stations had the least worsening trends. Region-average visibility was better before 1988 while worse after 1993 when comparing to the entire period, with the transition period of 1988-1993. The worst 20%, 50% and best 20% of region-average visibility

  8. Racial and ethnic differences in trends of end-stage renal disease: United States, 1995 to 2005.

    Science.gov (United States)

    Burrows, Nilka Ríos; Li, Yanfeng; Williams, Desmond E

    2008-04-01

    End-stage renal disease (ESRD) disproportionately affects racial/ethnic minority populations in the United States, whereas the prevalence of ESRD risk factors such as diabetes continues to increase. Using data from the US Renal Data System, we examined trends in ESRD incidence, including ESRD caused by diabetes or hypertension. We determined the total number of persons in the United States by race/ethnicity who began treatment during 1995 to 2005 for ESRD and for ESRD with diabetes or hypertension as the primary diagnosis. Incidence rates were calculated by using census data and age-adjusted based on the 2000 US standard population. Joinpoint regression was used to analyze trends. Overall, during 1995 to 2005, the age-adjusted ESRD incidence increased from 260.7 per million to 350.9 per million, but the rate of increase slowed from 1998 to 2005. In the 2000s, compared with the 1990s, the age-adjusted ESRD incidence has continued to increase but at a slower rate among whites and blacks and has decreased significantly among Native Americans, Asians, and Hispanics. The disparity gap in ESRD incidence between minority populations and whites narrowed during 1995 to 2005. Continued interventions to reduce the prevalence of ESRD risk factors are needed to decrease ESRD incidence.

  9. A nonlinear look at trend MFP growth and the business cycle: result from a hybrid Kalman/Markov switching model

    OpenAIRE

    Mark W. French

    2005-01-01

    The cycle in output and hours worked is not symmetric: it behaves differently around recessions than in expansions. Similarly, the trend in multifactor productivity (MFP) seems to pass through different regimes; there was an extended period of slow MFP growth from about 1973 through 1995, and faster growth thereafter. Typical linear models and linear filters such as the Kalman filter deal poorly with asymmetry and regime changes. This paper attempts to determine more accurately and quickly an...

  10. Energy conservation in the Netherlands 1995-2006. Including decomposition of the energy consumption trend; Energiebesparing in Nederland 1995-2007. Inclusief decompositie energieverbruikstrend

    Energy Technology Data Exchange (ETDEWEB)

    Gerdes, J.; Boonekamp, P.G.M. [ECN Beleidsstudies, Petten (Netherlands); Vreuls, H. [SenterNovem, Utrecht (Netherlands); Verdonk, M. [Planbureau voor de Leefomgeving PBL, Bilthoven (Netherlands); Pouwelse, J.W. [Centraal Planbureau CPB, Den Haag (Netherlands)

    2009-08-15

    Realized energy savings in the Netherlands for the period 1995-2007 are presented for the sectors households, industry, agriculture, services, transport, refineries and electricity, and on a national level. The figures on energy savings are based on the 'Protocol Monitoring Energy Savings', a common methodology and database for calculating energy savings. Results are presented for savings on final energy use, conversion in end-use sectors (co-generation) and conversion in the energy sector. National savings for the period 1995-2007 equal 0.9% per year on average, with a decreasing tendency in recent years. Continuing the trends of last year, the highest figure for end-use sectors is found for agriculture (2.6%) and the lowest figure for transport (0.1%). An uncertainty analysis reveals that the margin for the national savings figure is {+-}0.3 percent-point. At the request of PBL, a decomposition of the change in energy use into 14 different factors has been conducted. This shows that the growth of energy use from 1995 to 2007, if no savings would have been achieved, would have been almost twice as high. [Dutch] In dit rapport worden de energiebesparingcijfers gepresenteerd voor de periode 1995-2007, berekend volgens het Protocol Monitoring Energiebesparing (PME). De besparing wordt berekend voor de verbruiksectoren industrie, huishoudens, transport, land- en tuinbouw, diensten en raffinaderijen, de elektriciteitscentrales en het nationale niveau.

  11. Temporal trends in health-related quality of life after stroke: analysis from the South London Stroke Register 1995-2011.

    Science.gov (United States)

    Sheldenkar, Anita; Crichton, Siobhan; Douiri, Abdel; Rudd, Anthony G; Wolfe, Charles D A; Chen, Ruoling

    2014-08-01

    Survival after stroke has dramatically increased in the last two decades as the treatment of stroke has improved. However, time-trend analyses of health-related quality of life in stroke patients covering this time period are still not well investigated. The study aims to examine temporal trends in mental and physical health-related quality of life of stroke survivors between the period of 1995 and 2011. First in a lifetime strokes were registered in the South London Stroke Register between 1995 and 2011. Using the Short Form-12 Health Survey, trends in self-reported health-related quality of life at one-year after stroke were assessed over a 17-year period using linear regression, adjusting for socio-demographics, risk factors, and case-mix variables. Analyses stratifying by age, gender, race-ethnicity, and functional impairment were also performed. The overall trends of mental and physical health-related quality of life scores at one-year after stroke remained relatively unchanged over the period 1995-2011. However, mental health-related quality of life scores significantly improved between the period of 1995-2007 [β = 0·94 (95% CI; 0·15 to 1·74), P = 0·02], after which scores deteriorated [β = -2·02 (-3·82 to -0·22), P = 0·03]. Physical health-related quality of life scores remained stable until 2007, after which scores declined [β = -1·63 (-3·25 to -0·01), P = 0·05]. Despite declining health-related quality of life trends within the general population, stroke survivors' overall health-related quality of life remained unchanged, possibly due to lower expectations of health among stroke survivors. However, in recent years there has been a significant unexplained decline in both physical and mental health-related quality of life, suggesting that despite stroke policy aims to improve health-related quality of life, more needs to be done to target this decline. © 2014 The Authors. International Journal of Stroke © 2014 World

  12. Nitrate | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  13. Sunburn | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  14. River water quality at Galicia-Cost Basin during 1973-2002. Predictive analysis to 2010; Calidad del agua de los rios de la Cuenca Hidrografica Galicia-Costa durante el periodo 1973-1995. Analisis prdictivo a 2010

    Energy Technology Data Exchange (ETDEWEB)

    Heras Jimenez, A; las, de; Melgar Riol, M J

    2005-07-01

    The aim of the present work was to determine the water quality at the Mero, Ulla, Umia and Tambre river (Galicia), which belongs to the North river basin, as well as the problems associated to the contaminant contributions originated due to population changes. Industrial development and agriculture and live-sock activities during a 23 years period (1973-1995). Simiarly , the prediction of such changes till the year 2010 is also realized. The 26 analyzed parameters were obtained from the Database of the COCA-MOPU (Water Quality Control Web), and the were statistically analysed by means of the hierarchical cluster analysis, principal components multivariance analysis and the predictor techique for temporal series. Four different factors were identified: alkalinity, physical water characteristics, salinity and organic burden, with an accumulated variance of 60,2%. The predictive analysis adjusted to the ARIMA model shows the tendency to rise of variables defining alkalinity, salinity and organic burden, if present conditions are maintained. (Author) 25 refs.

  15. Time Trends and Educational Inequalities in Out-of-Hospital Coronary Deaths in Norway 1995-2009

    DEFF Research Database (Denmark)

    Sulo, Enxhela; Nygård, Ottar; Vollset, Stein Emil

    2017-01-01

    using Poisson regression analysis with year as the independent, continuous variable. Information on the highest achieved education was obtained from The National Education Database and classified as primary (up to 10 years of compulsory education), secondary (high school or vocational school......BACKGROUND: Recent time trends and educational gradients characterizing out-of-hospital coronary deaths (OHCD) are poorly described. METHODS AND RESULTS: We identified all deaths from coronary heart disease occurring outside the hospital in Norway during 1995 to 2009. Time trends were explored......), or tertiary (college/university). Educational gradients in OHCD were explored using Poisson regression, stratified by sex and age (

  16. Colorectal cancer mortality trends in Córdoba, Argentina.

    Science.gov (United States)

    Pou, Sonia Alejandra; Osella, Alberto Rubén; Eynard, Aldo Renato; Niclis, Camila; Diaz, María del Pilar

    2009-12-01

    Colorectal cancer is a leading cause of death worldwide for men and women, and one of the most commonly diagnosed in Córdoba, Argentina. The aim of this work was to provide an up-to-date approach to descriptive epidemiology of colorectal cancer in Córdoba throughout the estimation of mortality trends in the period 1986-2006, using Joinpoint and age-period-cohort (APC) models. Age-standardized (world population) mortality rates (ASMR), overall and truncated (35-64 years), were calculated and Joinpoint regression performed to compute the estimated annual percentage changes (EAPC). Poisson sequential models were fitted to estimate the effect of age (11 age groups), period (1986-1990, 1991-1995, 1996-2000 or 2001-2006) and cohort (13 ten-years cohorts overlapping each other by five-years) on colorectal cancer mortality rates. ASMR showed an overall significant decrease (EAPC -0.9 95%CI: -1.7, -0.2) for women, being more noticeable from 1996 onwards (EAPC -2.1 95%CI: -4.0, -0.1). Age-effect showed an important rise in both sexes, but more evident in males. Birth cohort- and period effects reflected increasing and decreasing tendencies for men and women, respectively. Differences in mortality rates were found according to sex and could be related to age-period-cohort effects linked to the ageing process, health care and lifestyle. Further research is needed to elucidate the specific age-, period- and cohort-related factors.

  17. Trends in leprosy case detection in Rwanda, 1995–2011: analysis of 17 years of laboratory data

    Directory of Open Access Journals (Sweden)

    Innocent Uwimana

    2017-02-01

    Objective: We analysed laboratory records to assess trends in prevalence rates and case detection rates (CDRs in Rwanda. Methods: A retrospective review of detected leprosy cases from the records of the Rwanda National Reference Laboratory over a 17-year period (1995–2011 was conducted. Skin biopsy samples were analysed microscopically using Ziehl-Neelsen staining technique to identify M. leprae. Results: Cumulatively, 266 suspected cases were reported between 1995 and 2011. Of the suspected cases, 77 (28.9% were laboratory confirmed as having leprosy. Among detected cases, 59 (76.6% were men and 18 (23.4% women. The male:female ratio was 3:1. There were 77 registered leprosy cases over the 17-year period of the study, and the prevalence rate was 0.005 per 10 000 population. A gradual decrease in the prevalence rate was observed from 0.015 per 10 000 population in 2003 to 0.003 per 10 000 population in 2010. From 1995 to 2011, the CDR did not exceed one per 10 000 population. Conclusion: This laboratory review demonstrates a declining trend in prevalence rates and CDR during the period of the study. Early case detection and a sustainable leprosy control programme remain the cornerstones of reducing the physical and socio-economic burden of leprosy in Rwanda.

  18. Epidemiology of ovarian cancer in Nagasaki city with reference to atomic bomb exposure, 1973∼1982

    International Nuclear Information System (INIS)

    Sasaki, Hidetaka; Shimokawa, Isao; Iwasaki, Keisuke; Matsuo, Takeshi; Ikeda, Takayoshi; Mine, Mariko; Mori, Hiroyuki

    1988-01-01

    Epidemiological study was conducted on 151 cases (67 exposed and 84 nonexposed) of ovarian cancer registered at the Nagasaki Tumor Registry from 1973 to 1982, with emphasis on the relation to radiation exposure. Although the crude incidence rate of ovarian cancer in the exposed group was higher than in the nonexposed group, the age-adjusted relative risk was not significantly different. The relative risk of ovarian cancer incidence by age at the time of the A-bomb was high in the 10-19 group (puberty), and was low in the 40-49 group. It suggested the possibility that radiation carcinogenesis in the ovary was closely related to the secondary excess of gonadotrophic hormones following radiation injury of the ovary. No significant different in histological type between the exposed and nonexposed groups could be found. (author)

  19. Trends in oil spills from tanker ships 1995-2004

    International Nuclear Information System (INIS)

    Huijer, K.

    2005-01-01

    The trends in oil spills around the world over from 1995 to 2004 were examined and analyzed for possible influences on spill volumes and frequencies for incidents of 3 spill size classes. The International Tanker Owners Pollution Federation (ITOPF) has maintained a database since 1974 of all oil spills from tankers, combined carriers and barges. The number of oil spills has decreased significantly in the last 30 years despite a steady increase in maritime oil trade since the 1980s. The recent trends were identified by causes, locations, oil type, and shipping legislation. The causes include ship loading/discharging, bunkering, collisions, groundings, hull failures and fires. The types of oil spilt include bunker, crude, cargo fuel, white product and some unknowns. It was concluded that the decline in oil spills is due to a range of initiatives taken by governments and the shipping industry rather than any one factor. Some notable influences towards reduced number of spills include: the international convention for the prevention of pollution from ships of 1972, as modified by the Protocol of 1978; the international convention for the safety of life at sea of 1974; and the Oil Pollution Act of 1990. Results of investigations into the causes of spills serve the purpose of informing the international process to further prevent and reduce marine oil pollution due to tankers. 7 refs., 5 tabs., 12 figs

  20. Financial Burden of Cancer Care | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  1. NCI Dictionary | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  2. Custom Report | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  3. Fat Consumption | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  4. Alcohol Consumption | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  5. Trends in nutrients and suspended solids at the Fall Line of five tributaries to the Chesapeake Bay in Virginia, July 1988 through June 1995

    Science.gov (United States)

    Bell, C.F.; Belval, D.L.; Campbell, J.P.

    1996-01-01

    Water-quality samples were collected at the Fall Line of five tributaries to the Chesapeake Bay in Virginia during a 6- to 7-year period. The water-quality data were used to estimate loads of nutrients and suspended solids from these tributaries to the non-tidal part of Chesapeake Bay Basin and to identify trends in water quality. Knowledge of trends in water quality is required to assess the effectiveness of nutrient manage- ment strategies in the five basins. Multivariate log-linear regression and the seasonal Kendall test were used to estimate flow-adjusted trends in constituent concentration and load. Results of multivariate log-linear regression indicated a greater number of statistically significant trends than the seasonal Kendall test; how-ever, when both methods indicated a significant trend, both agreed on the direction of the trend. Interpre- tation of the trend estimates for this report was based on results of the parametric regression method. No significant trends in total nitrogen concentration were detected at the James River monitoring station from July 1988 through June 1995, though total Kjeldahl nitrogen concen- tration decreased slightly in base-flow samples. Total phosphorus concentration decreased about 29 percent at this station during the sampling period. Most of the decrease can be attributed to reductions in point-source phosphorus loads in 1988 and 1989, especially the phosphate detergent ban of 1988. No significant trends in total suspended solids were observed at the James River monitoring station, and no trends in runoff- derived constituents were interpreted for this river. Significant decreases were detected in concentrations of total nitrogen, total Kjeldahl nitrogen, dissolved nitrite-plus-nitrate nitrogen, and total suspended solids at the Rappahannock River monitoring station between July 1988 and June 1995. A similar downward trend in total phosphorus concentration was significant at the 90-percent confidence level, but not the

  6. Epidemiology of ovarian cancer in Nagasaki city with reference to atomic bomb exposure, 1973/similar to/1982

    Energy Technology Data Exchange (ETDEWEB)

    Sasaki, Hidetaka; Shimokawa, Isao; Iwasaki, Keisuke; Matsuo, Takeshi; Ikeda, Takayoshi; Mine, Mariko; Mori, Hiroyuki

    1988-09-01

    Epidemiological study was conducted on 151 cases (67 exposed and 84 nonexposed) of ovarian cancer registered at the Nagasaki Tumor Registry from 1973 to 1982, with emphasis on the relation to radiation exposure. Although the crude incidence rate of ovarian cancer in the exposed group was higher than in the nonexposed group, the age-adjusted relative risk was not significantly different. The relative risk of ovarian cancer incidence by age at the time of the A-bomb was high in the 10-19 group (puberty), and was low in the 40-49 group. It suggested the possibility that radiation carcinogenesis in the ovary was closely related to the secondary excess of gonadotrophic hormones following radiation injury of the ovary. No significant different in histological type between the exposed and nonexposed groups could be found.

  7. Evaluation and application of multi-decadal visibility data for trend analysis of atmospheric haze

    Directory of Open Access Journals (Sweden)

    C. Li

    2016-03-01

    Full Text Available There are few multi-decadal observations of atmospheric aerosols worldwide. This study applies global hourly visibility (Vis observations at more than 3000 stations to investigate historical trends in atmospheric haze over 1945–1996 for the US, and over 1973–2013 for Europe and eastern Asia. A comprehensive data screening and processing framework is developed and applied to minimize uncertainties and construct monthly statistics of inverse visibility (1/Vis. This data processing includes removal of relatively clean cases with high uncertainty, and change point detection to identify and separate methodological discontinuities such as the introduction of instrumentation. Although the relation between 1/Vis and atmospheric extinction coefficient (bext varies across different stations, spatially coherent trends of the screened 1/Vis data exhibit consistency with the temporal evolution of collocated aerosol measurements, including the bext trend of −2.4 % yr−1 (95 % CI: −3.7, −1.1 % yr−1 vs. 1/Vis trend of −1.6 % yr−1 (95 % CI: −2.4, −0.8 % yr−1 over the US for 1989–1996, and the fine aerosol mass (PM2.5 trend of −5.8 % yr−1 (95 % CI: −7.8, −4.2 % yr−1 vs. 1/Vis trend of −3.4 % yr−1 (95 % CI: −4.4, −2.4 % yr−1 over Europe for 2006–2013. Regional 1/Vis and Emissions Database for Global Atmospheric Research (EDGAR sulfur dioxide (SO2 emissions are significantly correlated over the eastern US for 1970–1995 (r = 0.73, over Europe for 1973–2008 (r ∼ 0.9 and over China for 1973–2008 (r ∼ 0.9. Consistent "reversal points" from increasing to decreasing in SO2 emission data are also captured by the regional 1/Vis time series (e.g., late 1970s for the eastern US, early 1980s for western Europe, late 1980s for eastern Europe, and mid 2000s for China. The consistency of 1/Vis trends with other in situ measurements and emission data demonstrates promise in applying these quality assured 1/Vis data

  8. Comparability of [0-Level] GCE Grades in 1968 and 1973.

    Science.gov (United States)

    Backhouse, John K.

    1978-01-01

    Willmott's comparison of General Certificate of Education (GCE) scores in 1968 and 1973 is reexamined. The trend toward an increasing percentage of students who pass is confirmed, but estimates of standard errors indicate that subtest differences may be attributed to the sampling plan. (CP)

  9. Cancer Trends: Influencing Care and Research Priorities

    Science.gov (United States)

    Many of the trends being seen in cancer are changing how we view cancer and how we address it, from prompting research to identify the underlying causes of cancers increasing in incidence to informing research on treatment and prevention.

  10. Trends in leisure time and occupational physical activity in the Madrid region, 1995-2008.

    Science.gov (United States)

    Meseguer, Carmen M; Galán, Iñaki; Herruzo, Rafael; Rodríguez-Artalejo, Fernando

    2011-01-01

    Information on trends in physical activity is very scarce in Mediterranean countries, which have the highest sedentariness in Europe. This study describes recent trends in leisure time physical activity (LTPA) and at work in the Madrid region. The data were taken from representative annual surveys of population aged 18-64 years, between 1995-2008, 28,084 people participated. We calculated total energy, quantified in metabolic equivalent (MET-1 h per week), spent on LTPA and on light LTPA (6 MET). The annual change in LTPA was estimated by linear regression, and occupational activity by logistic regression, adjusting for age, gender and educational level. The total amount of LTPA in MET-1 h per week declined by 19.8% (Pgenders, all age groups and educational levels, except for those with the lowest level of education. The adjusted annual change in MET-1 h per week was: -0.21 (Pphysical inactivity has increased in the general population (odds ratio for annual change=1.01; 95% confidence interval, 1-1.02); specially in women, young and middle aged, and intermediate educational level. There has been a decline in LTPA, mainly in light and moderate activities, accompanied by greater occupational physical inactivity. This could have contributed to the increase in obesity in the Community of Madrid between 1995-2008. Copyright © 2010 Sociedad Española de Cardiología. Published by Elsevier Espana. All rights reserved.

  11. Trends in Costs of Thyroid Disease Treatment in Denmark during 1995-2015.

    Science.gov (United States)

    Møllehave, Line Tang; Linneberg, Allan; Skaaby, Tea; Knudsen, Nils; Ehlers, Lars; Jørgensen, Torben; Thuesen, Betina Heinsbæk

    2018-03-01

    Iodine fortification (IF) may contribute to changes in costs of thyroid disease treatment through changes in disease patterns. From a health economic perspective, assessment of the development in costs of thyroid disease treatment in the population is pertinent. To assess the trends in annual medicine and hospital costs of thyroid disease treatment during 1995-2015 in Denmark, i.e., before and after the introduction of mandatory IF in 2000. Information on treatments for thyroid disease (antithyroid medication, thyroid hormone therapy, thyroid surgery, and radioiodine treatment) was obtained from nationwide registers. Costs were valued at 2015 prices using sales prices for medicines and the Danish Diagnosis-Related Group (DRG) and Danish Ambulatory Grouping System (DAGS) tariffs of surgeries/radioiodine treatments. Results were adjusted for changes in population size and age and sex distribution. The total direct medicine and hospital costs of thyroid disease treatment increased from EUR ∼190,000 per 100,000 persons in 1995 to EUR ∼270,000 per 100,000 persons in 2015. This was mainly due to linearly increased costs of thyroid hormone therapy and increased costs of thyroid surgery since 2008. Costs of antithyroid medication increased slightly and transiently after IF, while costs of radioiodine treatment remained constant. Costs of thyroid hormone therapy and thyroid surgery did not follow the development in the prevalence of hypothyroidism and structural thyroid diseases observed in concurrent studies. The costs of total direct medicine and hospital costs for thyroid disease treatment in Denmark increased from 1995 to 2015. This is possibly due to several factors, e.g., changes in treatment practices, and the direct effect of IF alone remains to be estimated.

  12. Trends in childhood type 1 diabetes mellitus incidence in Beijing from 1995 to 2010: a retrospective multicenter study based on hospitalization data.

    Science.gov (United States)

    Gong, Chunxiu; Meng, Xi; Jiang, Yuwu; Wang, Xinli; Cui, Hong; Chen, Xiaobo

    2015-03-01

    The incidence of type 1 diabetes mellitus (T1DM) is increasing rapidly worldwide for children of every age group. A retrospective analysis of hospital registration data from five tertiary hospitals in Beijing, China, identified 485 patients (210 boys, 275 girls) younger than 15 years of age with newly diagnosed T1DM between 1995 and 2010. From 1995 to 2010, the incidence of T1DM in patients 1995 to 2010, with rates growing at an accelerated pace since 2006. Based on recent trends, we project continued rapid growth in the number of new childhood T1DM cases in Beijing.

  13. Overexpression of long intergenic noncoding RNA LINC00312 inhibits the invasion and migration of thyroid cancer cells by down-regulating microRNA-197-3p.

    Science.gov (United States)

    Liu, Kai; Huang, Wen; Yan, Dan-Qing; Luo, Qing; Min, Xiang

    2017-08-31

    The study evaluated the ability of long intergenic noncoding RNA LINC00312 (LINC00312) to influence the proliferation, invasion, and migration of thyroid cancer (TC) cells by regulating miRNA-197-3p. TC tissues and adjacent normal tissues were collected from 211 TC patients. K1 (papillary TC), SW579 (squamous TC), and 8505C (anaplastic TC) cell lines were assigned into a blank, negative control (NC), LINC00312 overexpression, miR-197-3p inhibitors, and LINC00312 overexpression + miR-197-3p mimics group. The expression of LINC00312, miR-197-3p , and p120 were measured using quantitative real-time PCR (qRT-PCR) and Western blotting. Cell proliferation was assessed via CCK8 assay, cell invasion through the scratch test, and cell migration via Transwell assay. In comparison with adjacent normal tissues, the expression of LINC00312 is down-regulated and the expression of miR-197-3p is up-regulated in TC tissues. The dual luciferase reporter gene assay confirmed that P120 is a target of miR-197-3p The expression of LINC00312 and p120 was higher in the LINC00312 overexpression group than in the blank and NV groups. However, the expression of miR-197-3p was lower in the LINC00312 overexpression group than in the blank and NC groups. The miR-197-3p inhibitors group had a higher expression of miR-197-3p , but a lower expression of p120 than the blank and NC groups. The LINC00312 overexpression and miR-197-3p inhibitor groups had reduced cell proliferation, invasion and migration than the blank and NC groups. These results indicate that a LINC00312 overexpression inhibits the proliferation, invasion, and migration of TC cells and that this can be achieved by down-regulating miR-197-3p . © 2017 The Author(s).

  14. Trends in truck freight energy use and carbon emissions in selected OECD countries from 1973 to 2005

    International Nuclear Information System (INIS)

    Kamakate, Fatumata; Schipper, Lee

    2009-01-01

    Trends in truck freight energy use and carbon emissions: In the age of global supply chains and 'just in time' logistics, fast and efficient goods movement is often seen as an economic imperative. Growth in global goods movement not only translates into growth in commercial trucking activity but also into growth in the share of trucking compared to other modes of in-country freight transportation. These trends have a significant impact on the energy intensity of freight transport. Using a bottom-up approach relying on national data, this study compares the energy intensity of truck freight in Australia, France, Japan, the United Kingdom and the United States from 1973 to the present. The analysis builds on previous work by and decomposing energy use for freight. Intensity is expressed in terms of vehicle intensity (megajoules/vehicle-kilometer), modal energy intensity (megajoules/tonne-kilometer), and carbon intensity (grams/tonne-km). The cross-country comparison highlights in part the influence of geography, transportation infrastructure, and truck utilization patterns on energy and carbon intensity from this sector. While improving fuel economy of individual vehicles is very important, large reductions in trucking energy use and emissions will also come from better logistics and driving, higher load factors, and better matching of truck capacity to load.

  15. Red Meat Consumption | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  16. Secondhand Smoke Exposure | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  17. Sun-Protective Behavior | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  18. Time trends, improvements and national auditing of rectal cancer management over an 18-year period.

    Science.gov (United States)

    Kodeda, K; Johansson, R; Zar, N; Birgisson, H; Dahlberg, M; Skullman, S; Lindmark, G; Glimelius, B; Påhlman, L; Martling, A

    2015-09-01

    The main aims were to explore time trends in the management and outcome of patients with rectal cancer in a national cohort and to evaluate the possible impact of national auditing on overall outcomes. A secondary aim was to provide population-based data for appraisal of external validity in selected patient series. Data from the Swedish ColoRectal Cancer Registry with virtually complete national coverage were utilized in this cohort study on 29 925 patients with rectal cancer diagnosed between 1995 and 2012. Of eligible patients, nine were excluded. During the study period, overall, relative and disease-free survival increased. Postoperative mortality after 30 and 90 days decreased to 1.7% and 2.9%. The 5-year local recurrence rate dropped to 5.0%. Resection margins improved, as did peri-operative blood loss despite more multivisceral resections being performed. Fewer patients underwent palliative resection and the proportion of non-operated patients increased. The proportions of temporary and permanent stoma formation increased. Preoperative radiotherapy and chemoradiotherapy became more common as did multidisciplinary team conferences. Variability in rectal cancer management between healthcare regions diminished over time when new aspects of patient care were audited. There have been substantial changes over time in the management of patients with rectal cancer, reflected in improved outcome. Much indirect evidence indicates that auditing matters, but without a control group it is not possible to draw firm conclusions regarding the possible impact of a quality control registry on faster shifts in time trends, decreased variability and improvements. Registry data were made available for reference. Colorectal Disease © 2015 The Association of Coloproctology of Great Britain and Ireland.

  19. [Regression analysis of the characteristics and outcome of colorectal cancer 1995 - 2007].

    Science.gov (United States)

    Chen, Chuang-qi; Fang, Le-kun; Ma, Jin-ping; Cai, Shi-rong; Dong, Wen-guang; Huang, Yi-hua; He, Yu-long; Zhan, Wen-hua

    2010-07-13

    To explore the clinical characteristics and the prognostic factors of patients with colorectal cancer. The data of 2042 cases of colorectal cancer, pathologically confirmed at our hospital from January 1995 to December 2007, were summarized and analyzed. The median age of all cases with colorectal cancer was 59 years old. The high-risk age ranged from 50 to 70 years old. The ratio of male and female was 1.4:1. The lesions located in rectum accounted for 46.2% and those for 22.0% in sigmoid. Patients under age 40 had a higher percentage of poor differentiation (33.5%) and mucinous carcinoma (16.7%). The cases with confirmed stage I, II, III and IV were 5.8%, 42.9%, 31.0% and 20.3% respectively. For all cases, the 1-, 3-, 5- and 10-year survival rates were 92.3%, 73.9%, 65.1% and 57.5% respectively. The independent risk factors for patient prognosis were age, gross type, differentiation, TNM staging and surgical type. Adjuvant chemotherapy was a protective factor. As compared with phase I (1995 - 2001), phase II (2002 - 2007) had a higher proportions of employing stapler, Dixon operation and adjuvant chemotherapy. The 1-, 3- and 5-year survival rates of phase II were higher than phase I (93.4%, 78.0% and 73.2% vs 90.6%, 69.2% and 58.8%). The prognostic factors of patients with colorectal cancer are age, gross type, differentiation, TNM staging, surgical type and adjuvant chemotherapy.

  20. Selected trends in breast cancer epidemiology in Slovakia

    International Nuclear Information System (INIS)

    Ondrusova, M.; Psenkova, M.; Mardiak, J.

    2015-01-01

    Introduction: Breast cancer is one of the most prevalent forms of malignant tumors in women and so poses a serious social and economic problem. Aims: By analysing the trends of the basic indicators of breast cancer descriptive epidemiology in Slovakia, the prospective development was predicted, providing the missing information needed to assess the impact of intervention programmes. Results: The age-standardised incidence of breast cancer in Slovakia shows a strongly rising trend by an annual percentage change value of 2.2%, whereby in respect of mortality, after a previous significant decrease in values recorded in the period 2000-2009, stabilisation is registered once again with an annual percentage change of 3.4% (without statistical significance). Conclusion: Adverse trends in the development of breast cancer mortality in Slovakia underline the importance of establishing and monitoring the efficacy of intervention steps as part of organised screening. (author)

  1. Panorama epidemiológico de la mortalidad por cáncer en el Instituto Mexicano del Seguro Social: 1991-1995 Epidemiologic panorama of cancer mortality in the Mexican Institute of Social Security: 1991-1995

    Directory of Open Access Journals (Sweden)

    JORGE SALMERÓN-CASTRO

    1997-07-01

    1991-1995, national and regional annual global cancer mortality as well as specific mortality rates for the 10 most important malignant neoplasms by sex were estimated among people older than 20 years of age. The trends for these neoplasms during the study period were estimated by means of Poisson regression. The rate differences in specific cancer mortality by region and sex, for the two major neoplasms, were calculated subtracting specific regional rates from the respective national rate in 1995. Results. The global mortality rate for cancer among men increased from 76.2 in 1991 to 94.8 x 100 000 IMSS´members in 1995; and among women from 85.6 to 105.8 x 100 000 IMSS´members, representing an increment of 24.4 and 24% men and women, respectively, during the study period. Among men, neoplasm of kidney, leukemia, pancreas, prostate and lung showed the major increment; among women, neoplasm of colon, breast, pancreas, leukemia and liver showed the most significant increment. Conclusions. In the IMSS it is necessary the integration of a population based cancer registry. The registry will play a main role in disease surveillance and control; will give basic information over incidence and temporal variation, and could be the main source of information for epidemiologic research, as well as planning and evaluation of the quality of medical attention services such as prevention and early diagnosis and treatment.

  2. Selected trends in lung cancer epidemiology in Slovakia

    International Nuclear Information System (INIS)

    Ondrusova, M.; Psenkova, M.; Berzinec, P.

    2015-01-01

    Introduction: The lung cancer is still among the dominant malignant tumors despite declining trend of incidence, especially in men, and also its adverse prognosis remains. Aim: The aim of the study was to analyse the development of long-term trends in incidence and mortality and to produce a prospective estimate of prevalence and overall burden of lung cancer in the population in the Slovak Republic. Results: A significant drop of incidence of the disease in men has been seen in Slovakia since 1988 by a mean annual percentage change of -2.16%, whereby mortality is declining a little faster (by an annual percentage change of -2.87%). Adverse trend has been registered in both indicators in case of lung cancer in women, with incidence rising since 2001 by 5.31% annually and mortality rising by 1.3% for the whole monitored period. Conclusion: The adverse rising trend in the incidence and mortality of lung cancer in women in the Slovak Republic, as well as the slower decline in incidence and mortality in men compared with some countries of Western Europe, will have an impact in future also on total costs for management of this disease. (author)

  3. Prognostic Performance and Reproducibility of the 1973 and 2004/2016 World Health Organization Grading Classification Systems in Non-muscle-invasive Bladder Cancer: A European Association of Urology Non-muscle Invasive Bladder Cancer Guidelines Panel Systematic Review.

    Science.gov (United States)

    Soukup, Viktor; Čapoun, Otakar; Cohen, Daniel; Hernández, Virginia; Babjuk, Marek; Burger, Max; Compérat, Eva; Gontero, Paolo; Lam, Thomas; MacLennan, Steven; Mostafid, A Hugh; Palou, Joan; van Rhijn, Bas W G; Rouprêt, Morgan; Shariat, Shahrokh F; Sylvester, Richard; Yuan, Yuhong; Zigeuner, Richard

    2017-11-01

    Tumour grade is an important prognostic indicator in non-muscle-invasive bladder cancer (NMIBC). Histopathological classifications are limited by interobserver variability (reproducibility), which may have prognostic implications. European Association of Urology NMIBC guidelines suggest concurrent use of both 1973 and 2004/2016 World Health Organization (WHO) classifications. To compare the prognostic performance and reproducibility of the 1973 and 2004/2016 WHO grading systems for NMIBC. A systematic literature search was undertaken incorporating Medline, Embase, and the Cochrane Library. Studies were critically appraised for risk of bias (QUIPS). For prognosis, the primary outcome was progression to muscle-invasive or metastatic disease. Secondary outcomes were disease recurrence, and overall and cancer-specific survival. For reproducibility, the primary outcome was interobserver variability between pathologists. Secondary outcome was intraobserver variability (repeatability) by the same pathologist. Of 3593 articles identified, 20 were included in the prognostic review; three were eligible for the reproducibility review. Increasing tumour grade in both classifications was associated with higher disease progression and recurrence rates. Progression rates in grade 1 patients were similar to those in low-grade patients; progression rates in grade 3 patients were higher than those in high-grade patients. Survival data were limited. Reproducibility of the 2004/2016 system was marginally better than that of the 1973 system. Two studies on repeatability showed conflicting results. Most studies had a moderate to high risk of bias. Current grading classifications in NMIBC are suboptimal. The 1973 system identifies more aggressive tumours. Intra- and interobserver variability was slightly less in the 2004/2016 classification. We could not confirm that the 2004/2016 classification outperforms the 1973 classification in prediction of recurrence and progression. This article

  4. Financial Burden of Cancer Care - Life After Cancer Summary Table | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  5. National Trends in Hemoglobin Concentration and Prevalence of Anemia among Chinese School-Aged Children, 1995-2010.

    Science.gov (United States)

    Song, Yi; Wang, Hai-Jun; Dong, Bin; Wang, Zhiqiang; Ma, Jun; Agardh, Anette

    2017-04-01

    To assess the trend of sex disparity in hemoglobin concentration and prevalence of anemia among Chinese school-aged children from 1995 to 2010. Data were collected from 360 866 children aged 7, 9, 12, 14, and 17 years during 4 cross-sectional surveys (1995, 2000, 2005, and 2010) of the Chinese National Surveys on Students Constitution and Health. Shifts in hemoglobin concentration distributions were compared by sex. Average shifts and sex differences were calculated with quantile regression models. Logistic regression was used to estimate the prevalence odds ratio of sex for prevalence of anemia in different surveys. The mean hemoglobin concentration increased among Chinese children between 1995 and 2010, from 132.7 to 138.3 g/L in boys, and from 127.7 to 132.3 g/L in girls. The prevalence of anemia decreased from 18.8% in 1995 to 9.9% in 2010. It was higher in rural than urban children among all age groups. The prevalence odds ratios of girls versus boys for anemia increased in both urban and rural areas over time. Hemoglobin concentration and prevalence of anemia improved among Chinese school-aged children over time. Hemoglobin concentration improved faster in boys than girls and as a result the relative prevalence of anemia in girls compared with boys increased. Sex-specific preventive guidelines and public health policies for childhood anemia are needed in China. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Trend Analysis of Cancer Mortality and Incidence in Panama, Using Joinpoint Regression Analysis.

    Science.gov (United States)

    Politis, Michael; Higuera, Gladys; Chang, Lissette Raquel; Gomez, Beatriz; Bares, Juan; Motta, Jorge

    2015-06-01

    Cancer is one of the leading causes of death worldwide and its incidence is expected to increase in the future. In Panama, cancer is also one of the leading causes of death. In 1964, a nationwide cancer registry was started and it was restructured and improved in 2012. The aim of this study is to utilize Joinpoint regression analysis to study the trends of the incidence and mortality of cancer in Panama in the last decade. Cancer mortality was estimated from the Panamanian National Institute of Census and Statistics Registry for the period 2001 to 2011. Cancer incidence was estimated from the Panamanian National Cancer Registry for the period 2000 to 2009. The Joinpoint Regression Analysis program, version 4.0.4, was used to calculate trends by age-adjusted incidence and mortality rates for selected cancers. Overall, the trend of age-adjusted cancer mortality in Panama has declined over the last 10 years (-1.12% per year). The cancers for which there was a significant increase in the trend of mortality were female breast cancer and ovarian cancer; while the highest increases in incidence were shown for breast cancer, liver cancer, and prostate cancer. Significant decrease in the trend of mortality was evidenced for the following: prostate cancer, lung and bronchus cancer, and cervical cancer; with respect to incidence, only oral and pharynx cancer in both sexes had a significant decrease. Some cancers showed no significant trends in incidence or mortality. This study reveals contrasting trends in cancer incidence and mortality in Panama in the last decade. Although Panama is considered an upper middle income nation, this study demonstrates that some cancer mortality trends, like the ones seen in cervical and lung cancer, behave similarly to the ones seen in high income countries. In contrast, other types, like breast cancer, follow a pattern seen in countries undergoing a transition to a developed economy with its associated lifestyle, nutrition, and body weight

  7. [Cancer incidence and mortality in some health districts in Brescia area 1993--1995].

    Science.gov (United States)

    Simonati, C; Limina, R M; Gelatti, U; Indelicato, A; Scarcella, C; Donato, F; Nardi, G

    2004-01-01

    Cancer Registries are an essential part of any rational programme of cancer control, for assessing the impact of cancer in the community, for health care planning and monitoring screening programmes, according to local enviromental problems. The Brescia Cancer Registry started in 1994 producing prevalence, incidence and mortality data using only manual procedures of colletting and processing data from clinical and pathological sources in Brescia in 1993--1995. Data quality indicators such as the percentages of istologically or cytologically verified cases and that of cases registered on the basis of Death Certificate Only (DCO) are similar to those from the other Northern Italian Registries. Incidence rates for all causes and for various common sites are higher in Brescia than in other areas covered by Cancer Registries in North of Italy.

  8. Salary-Trend Studies of Faculty for the Years 1992-93 and 1995-96 in the Following Academic Disciplines/Major Fields: Accounting, Art, General...Geology.

    Science.gov (United States)

    Howe, Richard D.

    This document provides comparative salary trend data for full-time faculty at 212 public and 337 private colleges and universities, based on two surveys, one for the baseline year 1992-93 and the other for the "trend" year 1995-96. For each of the 25 disciplines, a summary review provides a definition of the discipline; information on average…

  9. Upward trends in the use of community mental health and social work services in the Netherlands between 1979 and 1995 : are particular sociodemographic groups responsible?

    NARCIS (Netherlands)

    Have, M. ten; Meertens, V.; Scheepers, P.; Beekman, A.T.F.; Vollebergh, W.; Grotenhuis, Manfred Te

    2003-01-01

    Objective: We investigate 1) trends in use of community mental health care (CMHC) and community social work (CSW) by Dutch households in 1979–1995; 2) whether such trends can be explained by long-term relative changes in service use or in sizes of particular household categories. Method: Data was

  10. Trends of energy efficiency in Finnish road freight transport 1995-2009 and forecast to 2016

    International Nuclear Information System (INIS)

    Liimatainen, Heikki; Poellaenen, Markus

    2010-01-01

    A framework for modeling and analyzing the energy efficiency of road freight transport is presented in this paper. This framework is tested by using the data from the Finnish Goods Transport by Road statistics. The data was enhanced by calculating the fuel consumption for each trip in the data. To calculate this, weight-fuel consumption functions were estimated for each Euro-class vehicles and road type. This is a new method for analyzing the energy efficiency of road freight transport and it could be applied also in other countries gathering freight transport data with continuous company surveys. The analysis show that the energy efficiency of road freight transport in Finland improved during 1995-2002, but has declined since. The major drivers in the development have been the changes in the level of empty running and vehicle fuel efficiency. Extrapolating current statistical trends of factors that influence the energy efficiency show that the target set by the Finnish government for improving energy efficiency by 9% until 2016 will not be achieved. However, the target is possible to be achieved by a combination of small changes to some determinants. - Research highlights: →A new method for analyzing energy efficiency by adding fuel data to national freight statistics. →Energy efficiency improved in Finland from 1995 to 2002 but has declined since. →Energy efficiency in Finland is still on a good level internationally. →Target of the Finnish energy efficiency agreement was quantified for the first time in this study. →The target will not be achieved if the past trends continue.

  11. Coding completeness and quality of relative survival-related variables in the National Program of Cancer Registries Cancer Surveillance System, 1995-2008.

    Science.gov (United States)

    Wilson, Reda J; O'Neil, M E; Ntekop, E; Zhang, Kevin; Ren, Y

    2014-01-01

    Calculating accurate estimates of cancer survival is important for various analyses of cancer patient care and prognosis. Current US survival rates are estimated based on data from the National Cancer Institute's (NCI's) Surveillance, Epidemiology, and End RESULTS (SEER) program, covering approximately 28 percent of the US population. The National Program of Cancer Registries (NPCR) covers about 96 percent of the US population. Using a population-based database with greater US population coverage to calculate survival rates at the national, state, and regional levels can further enhance the effective monitoring of cancer patient care and prognosis in the United States. The first step is to establish the coding completeness and coding quality of the NPCR data needed for calculating survival rates and conducting related validation analyses. Using data from the NPCR-Cancer Surveillance System (CSS) from 1995 through 2008, we assessed coding completeness and quality on 26 data elements that are needed to calculate cancer relative survival estimates and conduct related analyses. Data elements evaluated consisted of demographic, follow-up, prognostic, and cancer identification variables. Analyses were performed showing trends of these variables by diagnostic year, state of residence at diagnosis, and cancer site. Mean overall percent coding completeness by each NPCR central cancer registry averaged across all data elements and diagnosis years ranged from 92.3 percent to 100 percent. RESULTS showing the mean percent coding completeness for the relative survival-related variables in NPCR data are presented. All data elements but 1 have a mean coding completeness greater than 90 percent as was the mean completeness by data item group type. Statistically significant differences in coding completeness were found in the ICD revision number, cause of death, vital status, and date of last contact variables when comparing diagnosis years. The majority of data items had a coding

  12. Burden of breast cancer in Cali, Colombia: 1962-2012.

    Science.gov (United States)

    Bravo, Luis Eduardo; García, Luz Stella; Carrascal, Edwin; Rubiano, Jaime

    2014-01-01

    To describe the behavior of breast cancer (BC)during the 1962-2012 period from information provided by the Cali Cancer Registry and the Municipal Health Secretariat of Cali. The incidence trend (1962-2007) and mortality trend (1984-2012) for breast cancer was studied and relative survival (RS)(1995-2004) was estimated. Age-standardized incidence and mortality rates to the world population (ASIR(w)/ASMR(w)) were expressed per 100000 persons-year. Their temporal trend was examined with the annual percent of change (APC), and the Cox model was used to analyze the variables that influenced the survival of women with breast cancer. The risk of breast cancer significantly increased in Cali through the 1962-2007 period, with an APC =1.7(95%CI:1.4-2.0). The ASIR(w) of BC increased from 27.1 in 1962 to 48.0 in 2007 and currently there are more than 500 cases reported annually. The mortality for BC has remained stable since 1984; in the 2009-2012 period, the ASMR(w) was 14.2. The 5-year RS was 69% (95%CI:66-71) from 2000-2004 and 62% (95%CI:59-65) from 1995-1999. The risk of death (HR) from BC was greater in persons from lower socioeconomic strata (SES) than from higher SES, HR=1.9(95%CI:1.3-2.9) and in those older than 70 years vs. <50, HR=1.6(95%CI:1.1-2.2). Mortality remained stable while incidence increased and survival improved, which may be associated with better detection and advances in treatment.

  13. Cost trend analysis of initial cancer treatment in Taiwan.

    Directory of Open Access Journals (Sweden)

    Tsai-Yun Li

    Full Text Available BACKGROUND: Despite the high cost of initial cancer care, that is, care in the first year after diagnosis, limited information is available for specific categories of cancer-related costs, especially costs for specific services. This study purposed to identify causes of change in cancer treatment costs over time and to perform trend analyses of the percentage of cancer patients who had received a specific treatment type and the mean cost of care for patients who had received that treatment. METHODOLOGY/PRINCIPAL FINDINGS: The analysis of trends in initial treatment costs focused on cancer-related surgery, chemotherapy, radiation therapy, and treatments other than active treatments. For each cancer-specific trend, slopes were calculated for regression models with 95% confidence intervals. Analyses of patients diagnosed in 2007 showed that the National Health Insurance (NHI system paid, on average, $10,780 for initial care of a gastric cancer patient and $10,681 for initial care of a lung cancer patient, which were inflation-adjusted increases of $6,234 and $5,522, respectively, over the 1996 care costs. During the same interval, the mean NHI payment for initial care for the five specific cancers increased significantly (p<0.05. Hospitalization costs comprised the largest portion of payments for all cancers. During 1996-2007, the use of chemotherapy and radiation therapy significantly increased in all cancer types (p<0.05. In 2007, NHI payments for initial care for these five cancers exceeded $12 billion, and gastric and lung cancers accounted for the largest share. CONCLUSIONS/SIGNIFICANCE: In addition to the growing number of NHI beneficiaries with cancer, treatment costs and the percentage of patients who undergo treatment are growing. Therefore, the NHI must accurately predict the economic burden of new chemotherapy agents and radiation therapies and may need to develop programs for stratifying patients according to their potential benefit

  14. Epidemiologic contributions to recent cancer trends among HIV-infected people in the United States.

    Science.gov (United States)

    Robbins, Hilary A; Shiels, Meredith S; Pfeiffer, Ruth M; Engels, Eric A

    2014-03-27

    HIV-infected people have elevated risk for some cancers. Changing incidence of these cancers over time may reflect changes in three factors: HIV population demographic structure (e.g. age distribution), general population (background) cancer rates, and HIV-associated relative risks. We assessed the contributions of these factors to time trends for 10 cancers during 1996-2010. Population-based registry linkage study. We applied Poisson models to data from the U.S. HIV/AIDS Cancer Match Study to estimate annual percentage changes (APCs) in incidence rates of AIDS-defining cancers [ADCs: Kaposi sarcoma, non-Hodgkin lymphoma (NHL), and cervical cancer] and seven non-AIDS-defining cancers (NADCs). We evaluated HIV-infected cancer trends with and without adjustment for demographics, trends in background rates, and trends in standardized incidence ratios (SIRs, to capture relative risk). Cancer rates among HIV-infected people rose over time for anal (APC 3.8%), liver (8.5%), and prostate (9.8%) cancers, but declined for Kaposi sarcoma (1996-2000: -29.3%; 2000-2010: -7.8%), NHL (1996-2003: -15.7%; 2003-2010: -5.5%), cervical cancer (-11.1%), Hodgkin lymphoma (-4.0%), and lung cancer (-2.8%). Breast and colorectal cancer incidence did not change over time. Based on comparison to adjusted models, changing demographics contributed to trends for Kaposi sarcoma and breast, colorectal, liver, lung, and prostate cancers (all P cancers. SIRs declined for ADCs, Hodgkin lymphoma (APC -3.2%), and lung cancer (-4.4%). Demographic shifts influenced several cancer trends among HIV-infected individuals. Falling relative risks largely explained ADC declines, while background incidence contributed to some NADC trends.

  15. Mortalidade por causas externas em crianças e adolescentes: tendências de 1979 a 1995 Child and adolescent mortality due to external causes: trends from 1979 to 1995

    Directory of Open Access Journals (Sweden)

    Maria Dilma de A Barros

    2001-04-01

    Full Text Available OBJETIVO: Analisar a magnitude e a tendência da mortalidade por grupos específicos de causas externas em crianças e adolescentes residentes no Recife, no período de 1979 a 1995. MÉTODOS: Foram utilizados os dados do Sistema de Informação em Mortalidade do Ministério da Saúde e da Secretaria de Saúde de Pernambuco. O grupo estudado, na faixa etária de 0-19 anos, representou 41,8% da população de Recife, em 1991. Utilizou-se o desenho ecológico exploratório tipo série temporal. Analisou-se a tendência para os coeficientes de mortalidade por causas externas e seus grupos específicos segundo sexo e grupo etário, por regressão linear simples. RESULTADOS E CONCLUSÕES: Na série temporal estudada, os coeficientes de mortalidade por causas externas mostraram crescimento, sobretudo por homicídios nos adolescentes, em que se observaram um aumento anual médio de 3,05 e um aumento relativo de 601, 3% ao longo da série. Em 1995, mais de 90% desses homicídios foram perpetrados por arma de fogo. Os dados revelam a magnitude do problema e a necessidade do seu enfrentamento, o qual precisa considerar a complexidade da determinação da violência.OBJECTIVE: To analyze the magnitude and trends of mortality due to external causes in specific age groups, from 0 to 19 years old in a population living in the city of Recife, Brazil, from 1979 to 1995. METHODS: Data from the Mortality Data System of the Ministry of Health and Health Department of Pernambuco State was used. The studied population, aged 0 to 19 years old, represented 41.8% of total city population in 1991. A time series exploratory ecological model was created to analyze trends in mortality coefficients due to external causes. Using simple linear regression these coefficients were assessed in specific age groups categorized by gender. RESULTS AND CONCLUSIONS: In the time series, mortality coefficients due to external causes showed an increasing trend, in particular due to

  16. Data Used in Analyses of Trends, and Nutrient and Suspended-Sediment Loads for Streams in the Southeastern United States, 1973-2005

    Science.gov (United States)

    Staub, Erik L.; Peak, Kelly L.; Tighe, Kirsten C.; Sadorf, Eric M.; Harned, Douglas A.

    2010-01-01

    Water-quality data from selected surface-water monitoring sites in the Southeastern United States were assessed for trends in concentrations of nutrients, suspended sediment, and major constituents and for in-stream nutrient and suspended-sediment loads for the period 1973-2005. The area of interest includes river basins draining into the southern Atlantic Ocean, the Gulf of Mexico, and the Tennessee River-drainage basins in Hydrologic Regions 03 (South Atlantic - Gulf) and 06 (Tennessee). This data assessment is related to studies of several major river basins as part of the U.S. Geological Survey National Water-Quality Assessment Program, which was designed to assess national water-quality trends during a common time period (1993-2004). Included in this report are data on which trend tests could be performed from 44 U.S. Geological Survey National Water Information System (NWIS) sampling sites. The constituents examined include major ions, nutrients, and suspended sediment; the physical properties examined include pH, specific conductance, dissolved oxygen, and streamflow. Also included are data that were tested for trends from an additional 290 sites from the U.S. Environmental Protection Agency Storage and Retrieval (STORET) database. The trend analyses of the STORET data were limited to total nitrogen and total phosphorus concentrations. Data from 48 U.S. Geological Survey NWIS sampling sites with sufficient water-quality and continuous streamflow data for estimating nutrient and sediment loads are included. The methods of data compilation and modification used prior to performing trend tests and load estimation are described. Results of the seasonal Kendall trend test and the Tobit trend test are given for the 334 monitoring sites, and in-stream load estimates are given for the 48 monitoring sites. Basin characteristics are provided, including regional landscape variables and agricultural nutrient sources (annual variations in cropping and fertilizer use

  17. Dietary patterns and colorectal cancer risk in middle-aged adults: A large population-based prospective cohort study.

    Science.gov (United States)

    Shin, Sangah; Saito, Eiko; Sawada, Norie; Ishihara, Junko; Takachi, Ribeka; Nanri, Akiko; Shimazu, Taichi; Yamaji, Taiki; Iwasaki, Motoki; Sasazuki, Shizuka; Inoue, Manami; Tsugane, Shoichiro

    2018-06-01

    A finding between dietary pattern and cancer may provide visions beyond the assessment of individual foods or nutrients. We examined the influence of dietary pattern with colorectal cancer (CRC) among a Japanese population. A total of 93,062 subjects (43,591 men, 49,471 women) who participated in the Japan Public Health Center-based Prospective Study were followed from 1995-1998 to the end of 2012, during which 2482 cases of CRC (1514 men, 968 women) were newly identified. Dietary data was obtained from a validated food-frequency questionnaire between 1995 and 1998. Three dietary pattern was derived from principal components factor: prudent, westernized, and traditional pattern. After controlled for potential confounders, the prudent pattern showed a decreased association of CRC risk in men (HR for highest quintile vs lowest: 0.85; 95% CI: 0.72-1.00; P trend cancer (P trend cancer in women (P trend pattern showed a significant positive linear trend for colon (P trend cancer (P trend dietary pattern on the overall or any specific sites risk of CRC. A prudent dietary pattern showed an inverse association with CRC risk in men, and a westernized pattern was related with a higher risk of colon and distal cancer in women. Copyright © 2017 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

  18. Trends in oral cavity, pharyngeal, oesophageal and gastric cancer mortality rates in Spain, 1952-2006: an age-period-cohort analysis.

    Science.gov (United States)

    Seoane-Mato, Daniel; Aragonés, Nuria; Ferreras, Eva; García-Pérez, Javier; Cervantes-Amat, Marta; Fernández-Navarro, Pablo; Pastor-Barriuso, Roberto; López-Abente, Gonzalo

    2014-04-11

    Although oral cavity, pharyngeal, oesophageal and gastric cancers share some risk factors, no comparative analysis of mortality rate trends in these illnesses has been undertaken in Spain. This study aimed to evaluate the independent effects of age, death period and birth cohort on the mortality rates of these tumours. Specific and age-adjusted mortality rates by tumour and sex were analysed. Age-period-cohort log-linear models were fitted separately for each tumour and sex, and segmented regression models were used to detect changes in period- and cohort-effect curvatures. Among men, the period-effect curvatures for oral cavity/pharyngeal and oesophageal cancers displayed a mortality trend that rose until 1995 and then declined. Among women, oral cavity/pharyngeal cancer mortality increased throughout the study period whereas oesophageal cancer mortality decreased after 1970. Stomach cancer mortality decreased in both sexes from 1965 onwards. Lastly, the cohort-effect curvature showed a certain degree of similarity for all three tumours in both sexes, which was greater among oral cavity, pharyngeal and oesophageal cancers, with a change point in evidence, after which risk of death increased in cohorts born from the 1910-1920s onwards and decreased among the 1950-1960 cohorts and successive generations. This latter feature was likewise observed for stomach cancer. While the similarities of the cohort effects in oral cavity/pharyngeal, oesophageal and gastric tumours support the implication of shared risk factors, the more marked changes in cohort-effect curvature for oral cavity/pharyngeal and oesophageal cancer could be due to the greater influence of some risk factors in their aetiology, such as smoking and alcohol consumption. The increase in oral cavity/pharyngeal cancer mortality in women deserves further study.

  19. Prostate cancer's hegemonic masculinity in select print mass media depictions (1974-1995).

    Science.gov (United States)

    Clarke, J N

    1999-01-01

    The meanings associated with prostate cancer were studied in contemporary mass print media. The study includes both manifest and latent content analysis of a period of approximately 2 decades, from 1974 to 1995. The manifest analysis revealed a primary emphasis on the importance of early detection. The latent analysis found that prostate cancer's presentation is gendered. Its description is embedded in themes related to masculinity, sexuality, competition, brotherhood, and machismo. This small, qualitative, and inductive study raises questions about the socially significant portrayal of the meanings of disease in the media, about the men who have been diagnosed with prostate cancer, have symptoms of prostate cancer, or about all men, because any man might at some time be diagnosed with prostate cancer. Stereotypical imaging could alienate men who either do not or do not want to fit into the stereotypical ideal as it is protrayed in the media. Such a portrayal also may have inplications for the potential willingness of men to engage in early detection, avail themselves of treatment, act preventatively, or become involved in lobbying for monies for research into the early prevention, detection, and treatment of prostate cancer.

  20. Trends in cancer mortality in Spain: the influence of the financial crisis.

    Science.gov (United States)

    Ferrando, Josep; Palència, Laia; Gotsens, Mercè; Puig-Barrachina, Vanessa; Marí-Dell'Olmo, Marc; Rodríguez-Sanz, Maica; Bartoll, Xavier; Borrell, Carme

    2018-02-13

    To determine if the onset of the economic crisis in Spain affected cancer mortality and mortality trends. We conducted a longitudinal ecological study based on all cancer-related deaths and on specific types of cancer (lung, colon, breast and prostate) in Spain between 2000 and 2013. We computed age-standardised mortality rates in men and women, and fit mixed Poisson models to analyse the effect of the crisis on cancer mortality and trends therein. After the onset of the economic crisis, cancer mortality continued to decline, but with a significant slowing of the yearly rate of decline (men: RR = 0.987, 95%CI = 0.985-0.990, before the crisis, and RR = 0.993, 95%CI = 0.991-0.996, afterwards; women: RR = 0.990, 95%CI = 0.988-0.993, before, and RR = 1.002, 95%CI = 0.998-1.006, afterwards). In men, lung cancer mortality was reduced, continuing the trend observed in the pre-crisis period; the trend in colon cancer mortality did not change significantly and continued to increase; and the yearly decline in prostate cancer mortality slowed significantly. In women, lung cancer mortality continued to increase each year, as before the crisis; colon cancer continued to decease; and the previous yearly downward trend in breast cancer mortality slowed down following the onset of the crisis. Since the onset of the economic crisis in Spain the rate of decline in cancer mortality has slowed significantly, and this situation could be exacerbated by the current austerity measures in healthcare. Copyright © 2018 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  1. Burden of breast cancer in Cali, Colombia: 1962-2012

    Directory of Open Access Journals (Sweden)

    Luis Eduardo Bravo

    2014-09-01

    Full Text Available Objective. To describe the behavior of breast cancer (BC during the 1962-2012 period from information provided by the Cali Cancer Registry and the Municipal Health Secretariat of Cali. Materials and methods. The incidence trend (1962-2007 and mortality trend (1984-2012 for breast cancer was studied and relative survival (RS(1995-2004 was estimated. Age-standardized incidence and mortality rates to the world population (ASIR(w/ASMR(w were expressed per 100 000 persons-year. Their temporal trend was examined with the annual percent of change (APC, and the Cox model was used to analyze the variables that influenced the survival of women with breast cancer. Results. The risk of breast cancer significantly increased in Cali through the 1962-2007 period, with an APC =1.7(95%CI:1.4-2.0. The ASIR(w of BC increased from 27.1 in 1962 to 48.0 in 2007 and currently there are more than 500 cases reported annually. The mortality for BC has remained stable since 1984; in the 2009-2012 period, the ASMR(w was 14.2. The 5-year RS was 69% (95%CI:66-71 from 2000-2004 and 62% (95%CI:59-65 from 1995-1999. The risk of death (HR from BC was greater in persons from lower socioeconomic strata (SES than from higher SES, HR=1.9(95%CI:1.3-2.9 and in those older than 70 years vs. menor que 50, HR=1.6(95%CI:1.1-2.2. Conclusion. Mortality remained stable while incidence increased and survival improved, which may be associated with better detection and advances in treatment.

  2. Age Effects and Temporal Trends in HPV-Related and HPV-Unrelated Oral Cancer in the United States: A Multistage Carcinogenesis Modeling Analysis.

    Directory of Open Access Journals (Sweden)

    Andrew F Brouwer

    Full Text Available Differences in prognosis in HPV-positive and HPV-negative oral (oropharyngeal and oral cavity squamous cell carcinomas (OSCCs and increasing incidence of HPV-related cancers have spurred interest in demographic and temporal trends in OSCC incidence. We leverage multistage clonal expansion (MSCE models coupled with age-period-cohort (APC epidemiological models to analyze OSCC data in the SEER cancer registry (1973-2012. MSCE models are based on the initiation-promotion-malignant conversion paradigm in carcinogenesis and allow for interpretation of trends in terms of biological mechanisms. APC models seek to differentiate between the temporal effects of age, period, and birth cohort on cancer risk. Previous studies have looked at the effect of period and cohort on tumor initiation, and we extend this to compare model fits of period and cohort effects on each of tumor initiation, promotion, and malignant conversion rates. HPV-related, HPV-unrelated except oral tongue, and HPV-unrelated oral tongue sites are best described by placing period and cohort effects on the initiation rate. HPV-related and non-oral-tongue HPV-unrelated cancers have similar promotion rates, suggesting similar tumorigenesis dynamics once initiated. Estimates of promotion rates at oral tongue sites are lower, corresponding to a longer sojourn time; this finding is consistent with the hypothesis of an etiology distinct from HPV or alcohol and tobacco use. Finally, for the three subsite groups, men have higher initiation rates than women of the same race, and black people have higher promotion than white people of the same sex. These differences explain part of the racial and sex differences in OSCC incidence.

  3. Time trends in the incidence of hysterectomy-corrected overall, type 1 and type 2 endometrial cancer in Denmark 1978-2014.

    Science.gov (United States)

    Faber, Mette Tuxen; Frederiksen, Kirsten; Jensen, Allan; Aarslev, Peter Bo; Kjaer, Susanne K

    2017-08-01

    To investigate time trends in the incidence of overall, type 1 and type 2 endometrial cancer in Denmark 1978-2014, correcting for hysterectomy. Based on the Danish Cancer Registry and the Danish National Patient Registry we calculated hysterectomy-corrected incidence rates of overall, type 1 and type 2 endometrial cancer. Separate analyses for women incidence with 95% confidence intervals (CI). The overall incidence of endometrial cancer decreased slightly from 1978 to 1995, but in the last two decades of the study period the incidence has been stable (APC=0.16; 95% CI: -0.19; 0.50). In the study period (1978-2014) type 1 endometrial cancer incidence decreased slightly (APC=-0.67; 95% CI:-0.83; -0.52), whereas the incidence of type 2 endometrial cancer increased substantially (APC=4.85; 95% CI: 4.47; 5.23). The decrease in type 1 endometrial cancer was most pronounced before 1996 in women younger than 55 years (APC=-2.79; 95% CI: -3.65; -1.91), while the largest increase in type 2 endometrial cancer was observed after 1996 (APC=6.42; 95% CI: 5.72; 7.12). Over a period of more than 35 years, the incidence of type 1 endometrial cancer decreased, mainly in pre- and perimenopausal women, while type 2 endometrial cancer incidence increased. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Long-term trends in the prevalence of patients hospitalized with ischemic stroke from 1995 to 2010 in Sweden.

    Directory of Open Access Journals (Sweden)

    Kok Wai Giang

    Full Text Available The prevalence of stroke is expected to increase partly because of prolonged life expectancy in the general population. The objective of this study was to investigate trends in the prevalence of patients hospitalized with ischemic stroke (IS in Sweden from 1995-2010.The Swedish inpatient and cause-specific death registries were used to estimate the absolute numbers and prevalence of patients who were hospitalized with and survived an IS from 1995-2010.The overall number of IS increased from 129,418 in 1995 to 148,778 in 2010. In 1995, the prevalence of IS was 189 patients per 10,000 population. An increase in overall prevalence was observed until 2000, and then it remained stable, followed by a decline with an annual percentage change of (APC -0.8% (95% CI -1.0 to 0.6 and with a final prevalence of 199 patients per 10,000 population in 2010. The prevalence of IS in people aged <45 years increased from 6.4 in 1995 to 7.6 patients per 10,000 population in 2010, with an APC of 2.1% (95% CI 0.9 to 3.4 from 1995-1998 and 0.7% (95% CI 0.6-0.9 from 1998-2010. Among those aged 45-54 years, the prevalence rose through the mid to late 1990s, followed by a slight decrease (APC: -0.7%, 95% CI-1.1 to -0.4 until 2006 and then remained stable with a prevalence of 43.8 patients per 10,000 population in 2010. Among ≥85 years, there was a minor decrease (APC: -0.3%, 95% CI -0.5 to -0.1 in overall prevalence after 2002 from 1481 to 1453 patients per 10,000 population in 2010.The overall prevalence of IS increased until 2000, but then remained stable followed by a slight decline. However, the prevalence of IS in the young increased through the study period. The absolute number of IS survivors has markedly increased, mainly because of demographic changes.

  5. Software Classifications: Trends in Literacy Software Publication and Marketing.

    Science.gov (United States)

    Balajthy, Ernest

    First in a continuing series of reports on trends in marketing and publication of software for literacy education, a study explored the development of a database to track the trends and reported on trends seen in 1995. The final version of the 1995 database consisted of 1011 software titles, 165 of which had been published in 1995 and 846…

  6. Tables of standardized mortality ratio for cancer in cities, towns and villages in Japan (1973-1987)

    International Nuclear Information System (INIS)

    Iwasaki, Tamiko; Fukuhisa, Kenjiro; Nishizawa, Kanae; Murata, Motoi; Kobayashi, Sadayoshi; Matsudaira, Hiromichi.

    1993-01-01

    This report contains tables of standardized mortality ratio(SMR) for cancer in cities, towns and villages in Japan. A survey is made only on several kinds of cancer which has (or possibly has) a relation to radiation, such as all malignant neoplasms, leukemia, acute non-lymphocytic leukemia, malignant lymphoma, non-hodgkin lymphoma(NHL), multiple myeloma, and malignant neoplasms of the lung and the thyroid. It is conducted by sex and by time period not only on all age group but also on age group from 0 to 24 (except malignant neoplasms of the lung and the thyroid) because raise of leukemia onset rate of the younger generation in peripheral area of reprocessing facilities becomes a problem. The term of survey is from 1973 to 1987 and divided into the whole term and every five years on available statistical data of dynamic population. SMR is calculated on each term by sex and municipalities. The results are shown on the tables. This report consists of 7 volumes. The volume No.2 contains tables of SMR for leukemia. (J.P.N.)

  7. Tables of standardized mortality ratio for cancer in cities, towns and villages in Japan (1973-1987)

    International Nuclear Information System (INIS)

    Iwasaki, Tamiko; Fukuhisa, Kenjiro; Nishizawa, Kanae; Murata, Motoi; Kobayashi, Sadayoshi; Matsudaira, Hiromichi.

    1993-01-01

    This report contains tables of standardized mortality ratio(SMR) for cancer in cities, towns and villages in Japan. A survey is made only on several kinds of cancer which has (or possibly has) a relation to radiation, such as all malignant neoplasms, leukemia, acute non-lymphocytic leukemia, malignant lymphoma, non-hodgkin lymphoma(NHL), multiple myeloma, and malignant neoplasms of the lung and the thyroid. It is conducted by sex and by time period not only on all age group but also on age group from 0 to 24 (except malignant neoplasms of the lung and the thyroid) because raise of leukemia onset rate of the younger generation in peripheral area of reprocessing facilities becomes a problem. The term of survey is from 1973 to 1987 and divided into the whole term and every five years on available statistical data of dynamic population. SMR is calculated on each term by sex and municipalities. The results are shown on the tables. This report consists of 7 volumes. The volume No.3 contains tables of SMR for acute non-lymphocytic leukemia. (J.P.N.)

  8. Tables of standardized mortality ratio for cancer in cities, towns and villages in Japan (1973-1987)

    International Nuclear Information System (INIS)

    Iwasaki, Tamiko; Fukuhisa, Kenjiro; Nishizawa, Kanae; Murata, Motoi; Kobayashi, Sadayoshi; Matsudaira, Hiromichi.

    1993-01-01

    This report contains tables of standardized mortality ratio(SMR) for cancer in cities, towns and villages in Japan. A survey is made only on several kinds of cancer which has (or possibly has) a relation to radiation, such as all malignant neoplasms, leukemia, acute non-lymphocytic leukemia, malignant lymphoma, non-hodgkin lymphoma(NHL), multiple myeloma, and malignant neoplasms of the lung and the thyroid. It is conducted by sex and by time period not only on all age group but also on age group from 0 to 24 (except malignant neoplasms of the lung and the thyroid) because raise of leukemia onset rate of the younger generation in peripheral area of reprocessing facilities becomes a problem. The term of survey is from 1973 to 1987 and divided into the whole term and every five years on available statistical data of dynamic population. SMR is calculated on each term by sex and municipalities. The results are shown on the tables. This report consists of 7 volumes. The volume No.4 contains tables of SMR for malignant lymphoma. (J.P.N.)

  9. Tables of standardized mortality ratio for cancer in cities, towns and villages in Japan (1973-1987)

    International Nuclear Information System (INIS)

    Iwasaki, Tamiko; Fukuhisa, Kenjiro; Nishizawa, Kanae; Murata, Motoi; Kobayashi, Sadayoshi; Matsudaira, Hiromichi.

    1993-01-01

    This report contains tables of standardized mortality ratio(SMR) for cancer in cities, towns and villages in Japan. A survey is made only on several kinds of cancer which has (or possibly has) a relation to radiation, such as all malignant neoplasms, leukemia, acute non-lymphocytic leukemia, malignant lymphoma, non-hodgkin lymphoma(NHL), multiple myeloma, and malignant neoplasms of the lung and the thyroid. It is conducted by sex and by time period not only on all age group but also on age group from 0 to 24 (except malignant neoplasms of the lung and the thyroid) because raise of leukemia onset rate of the younger generation in peripheral area of reprocessing facilities becomes a problem. The term of survey is from 1973 to 1987 and divided into the whole term and every five years on available statistical data of dynamic population. SMR is calculated on each term by sex and municipalities. The results are shown on the tables. This report consists of 7 volumes. The volume No. 1 contains tables of SMR for all malignant neoplasms. (J.P.N.)

  10. Tables of standardized mortality ratio for cancer in cities, towns and villages in Japan (1973-1987)

    International Nuclear Information System (INIS)

    Iwasaki, Tamiko; Fukuhisa, Kenjiro; Nishizawa, Kanae; Murata, Motoi; Kobayashi, Sadayoshi; Matsudaira, Hiromichi.

    1993-01-01

    This report contains tables of standardized mortality ratio(SMR) for cancer in cities, towns and villages in Japan. A survey is made only on several kinds of cancer which has (or possibly has) a relation to radiation, such as all malignant neoplasms, leukemia, acute non-lymphocytic leukemia, malignant lymphoma, non-hodgkin lymphoma(NHL), multiple myeloma, and malignant neoplasms of the lung and the thyroid. It is conducted by sex and by time period not only on all age group but also on age group from 0 to 24 (except malignant neoplasms of the lung and the thyroid) because raise of leukemia onset rate of the younger generation in peripheral area of reprocessing facilities becomes a problem. The term of survey is from 1973 to 1987 and divided into the whole term and every five years on available statistical data of dynamic population. SMR is calculated on each term by sex and municipalities. The results are shown on the tables. This report consists of 7 volumes. The volume No.6 contains tables of SMR for multiple myeloma. (J.P.N.)

  11. Referral rates and trends in radiotherapy as part of primary treatment of cancer in South Netherlands, 1988-2002

    International Nuclear Information System (INIS)

    Vulto, Ans; Louwman, Marieke; Rodrigus, Patrick; Coebergh, Jan Willem W.

    2006-01-01

    Background and purpose: To study referral rates and time trends in the use of primary radiotherapy (RT). Patients and Methods: The proportion and number of irradiated patients were calculated in a population-based setting among 58,436 cancer patients diagnosed between 1988 and 2002. Results: The number of patients receiving RT within 6 months of diagnosis (RT6mo) increased by about 3.3% annually, the proportion of all incident cases that received RT6mo remained stable (±30%). Only 20% of elderly patients (75+) received RT6mo. The proportion of cancer patients that received RT6mo increased markedly between 1988-1992 and 1998-2002 for patients with prostate cancer (15 and 28%, respectively), rectal cancer (33 and 43%) and brain tumours (48 and 67%). The absolute number of irradiated breast cancer patients increased 30% between 1988 and 2002. Among patients with rectal cancer, a shift occurred from postoperative to preoperative RT since 1995. The percentage of irradiated patients with stage I endometrial cancer decreased from 47% in 1988-1992 to 15% in 1998-2002. Conclusions: The percentage of cancer patients who received primary RT remained stable throughout 1988-2002, being consistently lower for older patients. The increased number of irradiated patients was due mainly to earlier detection and the ageing of the population. To clarify the overall percentage of patients irradiated, population-based studies on RT given after 6 months since diagnosis are warranted

  12. Cancer incidence among Mormons and non-Mormons in Utah (United States) 1995-1999.

    Science.gov (United States)

    Merrill, Ray M; Lyon, Joseph L

    2005-05-01

    Population-based Utah Cancer Registry data were linked with Latter-day Saint (LDS or Mormon) Church membership records to obtain site-specific cancer incidence for LDS and non-LDS populations in Utah during 1995-1999. Analyses were based on 27,631 incident cases of cancer identified among whites. Restriction to whites was made because of the small number of nonwhites, approximately 5%, in the state during the study period. The direct method was used to age-adjust the rates to the 2000 U.S. standard population. Significantly lower cancer incidence rates per 100,000 were observed among LDS compared with non-LDS males (287.2 vs. 321.1) and females (247.7 vs. 341.0). The lower rates are primarily explained by smoking-related cancers and female breast cancer. If the overall cancer incidence rate in LDS had occurred in the non-LDS population, 2.9% or 421 fewer cases would have occurred among males and 7.9% or 1,025 fewer cases would have occurred among females during the study period. Given our current knowledge of risk factors for cancer, differences between LDS and non-LDS in smoking for males and smoking and sexual and reproductive behaviors in females primarily explain the lower risk of cancer in LDS populations.

  13. Updating trends in cutaneous cancers in south-east Belgium.

    Science.gov (United States)

    Uhoda, Isabelle; Quatresooz, Pascale; Fumal, Isabelle; Nikkels, Arjen F; Piérard-Franchimont, Claudine; Piérard, Gerald E

    2004-07-01

    From data collected in a dermatopathology laboratory, the ratios between the numbers of specific cancers represent good markers for identifying any epidemiological shift in their prevalence and incidence among the reference population. The objective of the present study was to assess the ratios of the annual incidence of skin cancers in the Mosan region and Ardennes of Belgium over the past 6 years, and to compare the data with previous similar evaluations. A total of 7,640 skin cancers were collected and compared with regard to age and gender. Changes in time show that the trend of the increase in incidence of malignant melanoma (MM) is more impressive than that of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC). The age distribution of BCC and SCC confirms the increasing risk with ageing. By contrast, there is a steady decrease over the past decade in the mean age for MM, teenagers and young adults now form an expanding proportion of MM patients. There is an ongoing trend in diagnosing an increased number of skin cancers in our laboratory. This trend is particularly obvious for MM affecting young adults.

  14. Survey on the trends of atomic power development and utilization in 1973 fiscal year

    International Nuclear Information System (INIS)

    1975-01-01

    Japanese activities in the atomic power development and utilization during 1973 (FY) were investigated and compared with the previous year. The investigation was done for each type of organization; medical, educational, research institute, private company, and others. The results of the investigation can be summarized as follows. The total number of personnel being engaged in the field of atomic industry increased by 1.2%. About 52.8% of them belong to private companies. The number of trainees during 1973 increased by 7.9%. About 92.3% of them were trained in domestic organizations. The expenditure for research and development was 100 billion yen which is 12.1% larger than that in the previous year. About 73.4% was used by public research institutes including JAERI and PNC. Investment in equipments was 235.2 billion yen which was increase of 20%. Most of this money (215.4 billion yen) was invested for the construction of power plants by electric utilities. Total amount of production was 73 billion yen which was increase of 45.9%. (Aoki, K.)

  15. A Comparison of Foreign Direct Investments in Eurosian Countries to World Trend in the Period of 1995 - 2011

    Directory of Open Access Journals (Sweden)

    Hayri Tuzla

    2013-12-01

    Full Text Available The world which rapidly globalizes and where the boundaries diminish day by day, the foreign direct investments affect many diverse macroeconomic variables, specifically economic growth and unemployment. Most current studies support that there exists a strong causality relationship between foreign direct investments and economic growth.On the other hand, there exists a weaker positive causality relationship between economic growth and foreign direct investments. Moreover, it is an undeniable fact that the economic growth leads to a decline in unemployment. This study aims to compare the foreign direct investment trends of seven Eurasian countries (Azerbaijan, Kazakhstan, Kyrgyzstan, Tajikistan, Turkey, Turkmenistan and Uzbekistan in the period of 1995 and 2011. The results are compared to both the world foreign direct investment trend and the other Central Asian countries.

  16. Geographic Variation in Cancer Incidence among Children and Adolescents in Taiwan (1995–2009)

    Science.gov (United States)

    Hung, Giun-Yi; Horng, Jiun-Lin; Yen, Hsiu-Ju; Lee, Chih-Ying; Lee, Yu-Sheng

    2015-01-01

    Background Evidence from our recent study suggested that the overall trend for cancer incidence in children and adolescents has been increasing in Taiwan. Methods To analyze geographic variations in this trend, cancer frequencies and incidence rates of disease groups were quantified according to geographic areas among 12,633 patients aged Taiwan Cancer Registry. Three geographic levels were defined, namely county or city, region (Northern, Central, Southern, and Eastern Taiwan), and local administrative area (special municipality, provincial city, county-administered city, township, and aboriginal area). Results Of the regions, Northern Taiwan had the highest incidence rate at 139.6 per million person-years, followed by Central (132.8), Southern (131.8), and Eastern (128.4) Taiwan. Significantly higher standardized rate ratios (SRRs) were observed in Northern Taiwan (SRR = 1.06, 95% confidence interval [CI] = 1.02–1.10) and at the township level (SRR = 1.07, 95% CI = 1.03–1.11). Of the cities or counties, New Taipei City yielded the highest SRR (1.08), followed by Taipei City (SRR = 1.07). A comparison of the rates in the four regions and the remainder of Taiwan according to cancer type revealed that only the rate of neuroblastomas in Eastern Taiwan was significantly low. Trend analysis showed that the most significant increase in incidence rate was observed at the township level, with an annual percent change of 1.8% during the 15-year study period. Conclusions The high rate of childhood cancer in Northern Taiwan and at the township level deserves further attention. The potential impacts of environmental factors on the upward trend of childhood cancer incidence rate in townships warrant further investigation. PMID:26192415

  17. Trends of cervical cancer in Greenland

    DEFF Research Database (Denmark)

    Sander, Bente B; Rebolj, Matejka; Lynge, Elsebeth

    2014-01-01

    BACKGROUND: Due to its extraordinarily fast economic and social transition, virtually closed borders before 1940 and, moreover, that 85% of the population has the distinctive genetics of the Inuit, Greenland is a very interesting country to study cervical cancer from a historical perspective....... Nevertheless, little has been reported about long-term cancer trends in Greenland. Our aim was to describe and interpret the incidence of cervical cancer from 1950 to 2009. MATERIAL AND METHODS: We systematically searched PubMed for articles reporting the incidence of cervical cancer in Greenland. We...... supplemented this with data for 1980-2009 obtained from the Chief Medical Officer of Greenland. RESULTS: Incidence of cervical cancer was around 10 per 100 000 women (age-standardised, world population, ASW) in the 1950s, 30 per 100 000 in the 1960s, and in the 1980s around 60 per 100 000. From 1985 onwards...

  18. Incidence Trend and Epidemiology of Common Cancers in the Center of Iran.

    Science.gov (United States)

    Rafiemanesh, Hosein; Rajaei-Behbahani, Narjes; Khani, Yousef; Hosseini, Sayedehafagh; Pournamdar, Zahra; Mohammadian-Hafshejani, Abdollah; Soltani, Shahin; Hosseini, Seyedeh Akram; Khazaei, Salman; Salehiniya, Hamid

    2015-07-13

    Cancer is a major public health problem in Iran and many other parts of the world. The cancer incidence is different in various countries and in country provinces. Geographical differences in the cancer incidence lead to be important to conduct an epidemiological study of the disease. This study aimed to investigate cancer epidemiology and trend in the province of Qom, located in center of Iran. This is an analytical cross-sectional study carried out based on re-analysis cancer registry report and the disease management center of health ministry from 2004 to 2008 in the province of Qom. To describe incidence time trends, we carried out join point regression analysis using the software Join point Regression Program, Version 4.1.1.1. There were 3,029 registered cases of cancer during 5 years studied. Sex ratio was 1.32 (male to female). Considering the frequency and mean standardized incidence, the most common cancer in women were breast, skin, colorectal, stomach, and esophagus, respectively while in men the most common cancers included skin, stomach, colorectal, bladder, and prostate, respectively. There was an increasing and significant trend, according to the annual percentage change (APC) equal to 8.08% (CI: 5.1-11.1) for all site cancer in women. The incidence trend of all cancers was increasing in this area. Hence, planning for identifying risk factors and performing programs for dealing with the disease are essential.

  19. Trends in dietary patterns, alcohol intake, tobacco smoking, and colorectal cancer in Polish population in 1960-2008.

    Science.gov (United States)

    Jarosz, Mirosław; Sekuła, Włodzimierz; Rychlik, Ewa

    2013-01-01

    The study examined the relationships between long-term trends in food consumption, alcohol intake, tobacco smoking, and colorectal cancer (CRC) incidence. Data on CRC incidence rates were derived from the National Cancer Registry, on food consumption from the national food balance sheets; data on alcohol and tobacco smoking reflected official statistics of the Central Statistical Office. It was shown that CRC incidence rates were increasing between 1960 and 1995, which could have been affected by adverse dietary patterns (growing consumption of edible fats, especially animal fats, sugar, red meat, and declining fibre and folate intake), high alcohol consumption, and frequent tobacco smoking noted until the end of the 1980s. Since 1990, the dietary pattern changed favourably (decrease in consumption of red meat, animal fats, and sugar, higher vitamin D intake, increase in vegetables and fruit quantities consumed, and decline in tobacco smoking). These changes could contribute to the stabilisation of CRC incidence among women seen after 1996 and a reduction in the rate of increase among men.

  20. Annual report of waste generation and pollution prevention progress 1995

    International Nuclear Information System (INIS)

    1997-02-01

    This fourth Annual Report presents and analyzes 1995 DOE complex-wide waste generation and pollution prevention activities at 40 reporting sites in 25 States, and trends DOE waste generation from 1991 through 1995. DOE has established a 50% reduction goal (relative to the 1993 baseline) for routine operations radioactive and hazardous waste generation, due by December 31, 1999. Routine operations waste generation decreased 37% from 1994 to 1995, and 43% overall from 1993--1995

  1. Annual report 1973

    International Nuclear Information System (INIS)

    1973-01-01

    The GKSS scientific annual report summarizes the problems and results of the research and development projects of 1973. In contrast to earlier annual reports, a comprehensive description of the research facilities is not included. The annual report was extended by the paragraph 'Financial Report 1973' in the chapter 'Development of Geesthacht Research Centre'. The financial report gives a survey of the financial transactions and the major operations of the year under review. (orig./AK) [de

  2. Time trends in axilla management among early breast cancer patients

    DEFF Research Database (Denmark)

    Gondos, Adam; Jansen, Lina; Heil, Joerg

    2016-01-01

    Background We examined time trends in axilla management among patients with early breast cancer in European clinical settings. Material and methods EUROCANPlatform partners, including population-based and cancer center-specific registries, provided routinely available clinical cancer registry data...... for a comparative study of axillary management trends among patients with first non-metastatic breast cancer who were not selected for neoadjuvant therapy during the last decade. We used an additional short questionnaire to compare clinical care patterns in 2014. Results Patients treated in cancer centers were...... younger than population-based registry populations. Tumor size and lymph node status distributions varied little between settings or over time. In 2003, sentinel lymph node biopsy (SLNB) use varied between 26% and 81% for pT1 tumors, and between 2% and 68% for pT2 tumors. By 2010, SLNB use increased to 79...

  3. Medico-legal claims against English radiologists: 1995-2006.

    Science.gov (United States)

    Halpin, S F S

    2009-12-01

    A list of claims against radiologists from 1995-2006 was obtained from the NHS Litigation Authority. It shows a total of 440 claims. The largest number of claims (199) related to delayed or missed diagnoses of cancer, and 73 claims related to breast radiology. There is a trend for a mild increase in the number of claims each year. 30 claims were made after a false-positive diagnosis of cancer. Just under pound8.5 million has so far been paid in damages, with a further pound5 million in legal fees. A claim for multiple missed diagnoses of breast cancer led to a pay-out of pound464 000 ( pound673 000 after legal fees); the largest sum awarded following a delay in the diagnosis of an individual cancer was pound300 000. The subtle legal distinction between error and negligence is reviewed here. The reason why breast radiologists are more likely to be sued than any other type of British radiologist is also discussed, along with the implications for UK radiological practice, particularly in light of the recent Chief Medical Officer's report on revalidation. A method is proposed that may protect radiologists from allegations of clinical negligence in the future.

  4. Medicaid Coverage of Tobacco Dependency Treatments | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  5. UV Exposure and Sun Protective Practices | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  6. Smoke-free Workplace Rules and Laws | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  7. Diagnostic characteristics of lethal prostate cancer

    DEFF Research Database (Denmark)

    Helgstrand, John Thomas; Røder, Martin Andreas; Klemann, Nina

    2017-01-01

    eventually died from PCa. PATIENTS AND METHODS: Based on the national database, the Danish Prostate Cancer Registry, a nationwide population-based study of all 19,487 men who died from PCa in Denmark between 1995 and 2013 was conducted. Trends in median survival and trends in age, prostate-specific antigen......BACKGROUND: The diagnostic characteristics of men who eventually die from prostate cancer (PCa) and the extent to which early diagnostic strategies have affected these characteristics are unclear. We aimed to investigate trends in survival and clinical presentation at diagnosis in men who...... significantly over time, parallelled by an increase in median survival. Taken together, this indicates a lead-time effect on survival, which presently, however, is not substantial enough to result in a reduced PCa-specific mortality....

  8. World uranium production in 1995

    International Nuclear Information System (INIS)

    Anon.

    1996-01-01

    For the first time since the political and economic opening of the former Soviet Union and Eastern Europe, world uranium production actually increased in 1995. Preliminary estimates for 1996 continue this trend, indicating additional (if slight) production increases over 1995 levels. Natural uranium production increased by about 5% in 1995 to 34,218 tons uranium or 89 Mlbs U3O8. This is an increase of approximately 1700 tons of uranium or 4.3 Mlbs of U3O8 over the updated 1994 quantities. Data is presented for each of the major uranium producing countries, for each of the world's largest uranium mines, for each of the world's largest corporate producers, and for major regions of the world

  9. Trends in vehicular emissions in China's mega cities from 1995 to 2005

    International Nuclear Information System (INIS)

    Wang Haikun; Fu Lixin; Zhou Yu; Du Xuan; Ge Weihua

    2010-01-01

    Multiyear inventories of vehicular emissions in Beijing, Shanghai and Guangzhou from 1995 through 2005 have been developed in this paper to study the vehicle emissions trends in China's mega cities during the past decade. The results show that the vehicular emissions of CO, HC, NO x and PM 10 have begun to slow their growth rates and perhaps even to decline in recent years due to the implementation of measures to control vehicular emissions in these cities. However, vehicular CO 2 emissions have substantially increased and still continue to grow due to little fuel economy improvement. Passenger cars and large vehicles (including heavy duty trucks and buses) are the major sources of vehicular CO 2 and CO emissions while large vehicles were responsible for nearly 70% and 80% of the vehicular NO x and PM 10 emissions in these mega cities. Motorcycles are also important contributors to vehicular emissions in Guangzhou and Shanghai. - The vehicular emissions (except CO 2 ) in China's mega cities have begun to slow their rates of growth and even to decline during the past decade.

  10. Time Trends in Breast Cancer Among Indian Women Population: An Analysis of Population Based Cancer Registry Data.

    Science.gov (United States)

    Chaturvedi, Meesha; Vaitheeswaran, K; Satishkumar, K; Das, Priyanka; Stephen, S; Nandakumar, A

    2015-12-01

    The trends observed in cancer breast among Indian women are an indication of effect of changing lifestyle in population. To draw an appropriate inference regarding the trends of a particular type of cancer in a country, it is imperative to glance at the reliable data collected by Population Based Cancer Registries over a period of time. To give an insight of changing trends of breast cancer which have taken place over a period of time among women in Cancer Registries of India. Breast Cancer trends for invasive breast cancer in women in Indian Registries have varied during the selected period. Occurrence of breast cancers has also shown geographical variation in India. This data was collected by means of a 'Standard Core Proforma' designed by NCRP conforming to the data fields as suggested by International norms. The Proforma was filled by trained Registry workers based on interview/ hospital medical records/ supplementing data by inputs from treating surgeons/radiation oncologists/involved physicians/pathologists. The contents of the Proforma are entered into specifically created software and transmitted electronically to the coordinating center at Bangalore. The registries contributing to more number of years of data are called as older registries, while other recently established registries are called newer registries. While there has been an increase recorded in breast cancer in most of the registries, some of them have recorded an insignificant increase. Comparison of Age Adjusted Rates (AARs) among Indian Registries has been carried out after which trends observed in populations covered by Indian Registries are depicted. A variation in broad age groups of females and the proneness of females developing breast cancer over the period 1982 to 2010 has been shown. Comparisons of Indian registries with International counterparts have also been carried out. There are marked changes in incidence rates of cancer breast which have occurred in respective registries in a

  11. PECAN PRODUCTION AND PRICE TRENDS 1979-1995

    OpenAIRE

    Shafer, Carl E.

    1996-01-01

    Pecan production, stocks, trade and prices are described. Data on tree nuts believed to compete with pecans are also presented. Pecan production and prices became more volatile in the early 1990's. Prices reached exceptionally high levels during five of the six years 1990-1995. US pecan imports have increased significantly since the mid-1980's and clearly exceed exports. Production, cold storage stocks, and inflation explained most of the year-to-year changes in season average pecan price lev...

  12. Trends in Canadian Sociology Master's Theses in Relation to Research Ethics Review, 1995-2004.

    Science.gov (United States)

    van den Hoonaard, Will C

    2006-12-01

    THIS PAPER EXAMINES TRENDS IN CANADIAN Master's theses in sociology, 1995-2004, in the course the implementation of Canada's national research-ethics guidelines (2001), using data available from ProQuest Dissertations. While there has been no decline in the number of theses completed during this period, nearly 1/4 fewer theses now involve research participants. The proportion of theses using quantitative methods shows decline; theses using qualitative methods, however, have increased significantly over time. A closer inspection qualitative theses shows an impressive increase in the proportion of theses using interviews, while the decrease in theses using field work is even more dramatic, from 40% to 5%. The decrease of theses involving field work is particularly alarming for a significant segment of sociology that must derive its material mainly from field work. Data drawn from a larger study supplement the findings in this article.

  13. Epidemiology of cancers of the liver, gall bladder, extrahepatic bile duct and pancreas in Nagasaki city from 1973 to 1982 with reference to atomic bomb exposure

    International Nuclear Information System (INIS)

    Takeshima, Fuminao; Shimokawa, Isao; Takashima, Kazuhiko

    1990-01-01

    This epidemiology study included 808 cases of liver cancers, 378 cases of gall bladder and extrahepatic bile duct cancer, and 312 cases of pancreas cancer registered at the Nagasaki Tumor Registry from 1973 to 1982, with emphasis on the relationship of these cancers to radiation exposure. The incidence of liver, gall bladder and extrahepatic bile duct cancer in both sexes tended to be higher in A-bomb survivors than in the nonexposed population, but were particularly significantly higher in male A-bomb survivors in each age-adjusted relative risk group. The incidence of pancreas cancer in females tended to be higher among A-bomb survivors than in the nonexposed population, and age-adjusted relative risk was significantly higher for female A-bomb survivors. No significant differences in relative distribution of histological type between exposed and nonexposed groups was observed. (author)

  14. Trends in x-ray photography and patient exposure dose. Questionnaire survey results compared with those in 1973. [questionnaire survey in 1979

    Energy Technology Data Exchange (ETDEWEB)

    Orito, T; Sanada, S; Maekawa, R; Koshida, K; Hiraki, T [Kanazawa Univ. (Japan). School of Paramedicine

    1980-04-01

    The exposure doses of patients in X-ray photography are influenced by such technological factors as X-ray tube voltage, filter, sensitizing screen, film and grid. Survey by questionnnaire was made previously in 1973 on the above factors. The trends five years after were surveyed similarly, in connection with the exposure doses of patients. Questionnaires were sent to 200 radiation technicians, and 121 (60.5%) answered the survey in March, 1979. The results in the cases of simple X-ray photography and obstetric, infant and breast X-ray photographings are described. X-ray tube voltage is generally on the increase. In the sensitizing screens, exposure doses are fairly decreased due to the use of improved intensifying screen (LT-II). In the grid, the ratio 8 : 1 is used more than 5 : 1. In the usage of additional filters and in the distance of photography, improvements are desired.

  15. Epidemiology Characteristics and Trends of Lung Cancer Incidence in Iran.

    Science.gov (United States)

    Almasi, Zeinab; Salehiniya, Hamid; Amoori, Neda; Enayatrad, Mostafa

    2016-01-01

    Lung cancer is one of the most common cancers in the world and a major cause of death from cancer. One of the important indicators to compare the prevalence and incidence of the disease is a change in the trend. The aim of this study was to investigate the changes in the incidence of lung cancer in Iran. This study was conducted based on existing data obtained from a national registry of cancer cases and the Disease Management Center of Ministry of Health in Iran. All cases registered in the country were included during 2003-2008. Incidence rates were reported based on the direct method and standard population of World Health Organization. The study also examined the morphology of common lung cancers. Trends in incidence underwent joinpoint regression analysis. Based on the results of this study, 14,403 cases of lung cancer have been recorded of which 10,582 cases were in men and 3,821 in women. Highest incidence rates were observed in the 80-84 age group. Considerable variation across provinces was evident. In females squamous cell carcinoma (SCC) demonstrated a reduction from 24% to 16% of lesions over the period of study, while adenocarcinoma rose from 21% to 29%. In males a similar reduction in SCC was apparent (42% to 29%, again with increase in AC (13 % to 18%). The results show that the increase in the incidence of lung cancer the trend is that more men than women and in men and may be caused by changes in smoking pattern. The incidence of lung cancer in the North West and West provinces was higher than in other regions.

  16. Authoritarian Personalities, 1950-1973

    Science.gov (United States)

    Whitten, Norman E.

    1976-01-01

    American college graduates of the post Kent State era are compared with those of the post Hitler era as to authoritarian type personality. A short rating scale, which is included in the article, administered to graduates in 1950 was again administered to graduates of the same college in 1973. The 1973 group was less authoritarian than the 1950…

  17. Tables of standardized mortality ratio for cancer in cities, towns and villages in Japan (1973-1987)

    International Nuclear Information System (INIS)

    Iwasaki, Tamiko; Fukuhisa, Kenjiro; Nishizawa, Kanae; Murata, Motoi; Kobayashi, Sadayoshi; Matsudaira, Hiromichi.

    1993-01-01

    This report contains tables of standardized mortality ratio(SMR) for cancer in cities, towns and villages in Japan. A survey is made only on several kinds of cancer which has (or possibly has) a relation to radiation, such as all malignant neoplasms, leukemia, acute non-lymphocytic leukemia, malignant lymphoma, non-hodgkin lymphoma(NHL), multiple myeloma, and malignant neoplasms of the lung and the thyroid. It is conducted by sex and by time period not only on all age group but also on age group from 0 to 24 (except malignant neoplasms of the lung and the thyroid) because raise of leukemia onset rate of the younger generation in peripheral area of reprocessing facilities becomes a problem. The term of survey is from 1973 to 1987 and divided into the whole term and every five years on available statistical data of dynamic population. SMR is calculated on each term by sex and municipalities. The results are shown on the tables. This report consists of 7 volumes. The volume No.7 contains tables of SMR for malignant neoplasms of the lung and the thyroid. (J.P.N.)

  18. Racial disparities in cancer-related survival in patients with squamous cell carcinoma of the esophagus in the US between 1973 and 2013.

    Directory of Open Access Journals (Sweden)

    Alice Kim

    Full Text Available Esophageal cancer makes up approximately 1% of all diagnosed cancers in the US. There is a persistent disparity in incidence and cancer-related mortality rates among different races for esophageal squamous cell carcinoma (SCC. Most previous studies investigated racial disparities between black and white patients, occasionally examining disparities for Hispanic patients. Studies including Asians/Pacific Islanders (API as a subgroup are rare. Our objective was to determine whether there is an association between race and cancer-related survival in patients with esophageal SCC.This was a retrospective cohort study using the National Cancer Institute's Surveillance, Epidemiology, and End Result (SEER database. The SEER registry is a national database that collects information on all incident cancer cases in 13 states of the United States and covers nearly 26% of the US population Patients aged 18 and over of White, Black, or Asian/Pacific Islander (API race with diagnosed esophageal SCC from 1973 to 2013 were included (n = 13,857. To examine overall survival, Kaplan-Meier curves were estimated for each race and the log-rank test was used to compare survival distributions. Cox proportional hazards models were used to estimate unadjusted and adjusted hazard ratios with 95% confidence intervals. The final adjusted model controlled for sex, marital status, age at diagnosis, decade of diagnosis, ethnicity, stage at diagnosis, and form of treatment. Additional analyses stratified by decade of diagnosis were conducted to explore possible changes in survival disparities over time. After adjustment for potential confounders, black patients had a statistically significantly higher hazard ratio compared to white patients (HR 1.08; 95% confidence interval (CI 1.03-1.13. However, API patients did not show a statistically significant difference in survival compared with white patients (HR 1.00; 95% CI 0.93-1.07. Patients diagnosed between 1973 and 1979 had twice

  19. Bibliometrics study on authorship trends in periodontal literature from 1995 to 2010.

    Science.gov (United States)

    Geminiani, Alessandro; Ercoli, Carlo; Feng, Changyong; Caton, Jack G

    2014-05-01

    Biomedical research has grown considerably in the last few decades, and the authorship characteristics of the dental literature as a whole and of its specialty fields has changed significantly. Unfortunately, the bibliometrics of the periodontal literature have not been thoroughly investigated. The aim of this study is to investigate the bibliometrics of periodontal literature, assessing the geographic origin, study design, and topics investigated in periodontal research published from 1995 to 2010. Articles published in periodontal journals during 1995 to 2010 were retrieved through hand search. Inclusion/exclusion criteria were applied. The following variables were extrapolated from each article: number of authors, study design, topic investigated, financial support, and geographic origin. The general linear model assessed the influence of independent variables on number of authors per article, and χ(2) test assessed the statistical difference of the variables over years 1995 to 2010. A total of 2,260 articles were reviewed; 2,076 met the inclusion criteria. The number of authors per article increased (P <0.001) from 4.0 (1995) to 5.1 (2010). The proportion of articles published from North America and Europe decreased (P <0.001) from 84.3% (1995) to 58.6% (2010), whereas for Asia and South America the article proportion increased (P <0.001) from 13.8% (1995) to 40% (2010). Research targeting prevention and treatment of periodontal disease is decreasing (P <0.001) in favor of implant-related research. Governmental research funding is increasing (P <0.001). Periodontal research significantly changed during the last 15 years.

  20. Trends in Female Breast Cancer by Age Group in the Chiang

    Science.gov (United States)

    Sripan, Patumrat; Sriplung, Hutcha; Pongnikorn, Donsuk; Virani, Shama; Bilheem, Surichai; Chaisaengkhaum, Udomlak; Maneesai, Puttachart; Waisri, Narate; Hanpragopsuk, Chirapong; Tansiri, Panrada; Khamsan, Varunee; Poungsombat, Malisa; Mawoot, Aumnart; Chitapanarux, Imjai

    2017-05-01

    Objectives: This study was conducted to determine incidence trends of female breast cancer according to age groups and to predict future change in Chiang Mai women through 2028. Method: Data were collected from all hospitals in Chiang Mai in northern Thailand, from 1989 through 2013, and used to investigate effects of age, year of diagnosis (period) and year of birth (cohort) on female breast cancer incidences using an age-period-cohort model. This model features geometric cut trends to predict change by young (<40 years), middle-aged (40-59) and elderly (≥60) age groups. Result: Of 5, 417 female breast cancer patients with a median age of 50 years (interquartile range: 43 to 59 years), 15%, 61% and 24% were young, middle-aged and elderly, respectively. Seventy nine percent of cancer cases in this study were detected at advanced stage. The trend in stage classification showed an increase in percentage of early stage and a decrease in metastatic cancers. Linear trends for cohort and period were not found in young females but were observed in middle-aged and elderly groups. Age-standardized rates (ASR) can be expected to remain stable around 6.8 per 100,000 women-years in young females. In the other age groups, the ASR trends were calculated to increase and reach peaks in 2024 of 120.2 and 138.2 per 100,000 women-years, respectively. Conclusion: Cohort effects or generation-specific effects, such as life style factors and the year of diagnosis (period) might have impacted on increased incidence in women aged over 40 years but not those under 40 years. A budget should be provided for treatment facilities and strategies to detect early stage cancers. The cost effectiveness of screening measures i.e. mammographic screening may need to be reconsidered for women age over 40 years. Creative Commons Attribution License

  1. Changing Trends in oral cancer - a global scenario

    Science.gov (United States)

    Gupta, Neha; Acharya, Arun Kumar; Patthi, Basavaraj; Goud, Venkatesh; Reddy, Somanath; Garg, Anshul; Singla, Ashish

    2016-01-01

    Oral cancer is one of the highly prevalent cancers worldwide and a leading cause of mortality in certain regions like South-Central Asia. It is a major public health problem. Late diagnosis, high mortality rates and morbidity are characteristics of the disease worldwide. For control of oral cancer an idea of the coverage of the same in the various regions is necessary. The estimated incidence, mortality and 5-year survival due to lip, oral cavity cancer in world is 3, 00, 373(2.1%), 1, 45, 328(1.8%) and 7, 02, 149(2.2%) respectively according to data of GLOBOCAN 2012. A changing trend in incidence and prevalence of oral cancer has been observed with more women and youngsters being affected by oral cancer. PMID:28804673

  2. Comorbidity and age affect treatment policy for cervical cancer: a population-based study in the south of The Netherlands, 1995-2004

    NARCIS (Netherlands)

    van der Aa, M.A.; Siesling, Sabine; Kruitwagen, R.F.P.M.; Lybeert, M.L.M.; Coebergh, J.W.W.; Janssen-Heijnen, M.L.G.

    2008-01-01

    OBJECTIVE: The aim of this study was to estimate the effects of age and comorbidity on the choice of treatment modalities and prognosis for patients with cervical cancer. METHODS: All patients with cervical cancer newly diagnosed between 1995 and 2004 (n=775) were selected from the population-based

  3. Trends of Social Inequalities in the Specific Causes of Infant Mortality in a Nationwide Birth Cohort in Korea, 1995-2009.

    Science.gov (United States)

    Son, Mia; An, Soo Jeong; Kim, Young Ju

    2017-09-01

    The relationship between social disparity and specific causes of infant mortality has rarely been studied. The present study analyzed infant mortality trends according to the causes of death and the inequalities in specific causes of infant mortality between different parental social classes. We analyzed 8,209,836 births from the Statistics Korea between 1995 and 2009. The trends of disparity for cause-specific infant mortality according to parental education and employment were examined using the Cox proportional hazard model for the birth-year intervals of 1995-1999, 2000-2004, and 2005-2009. Adjusted hazard ratios were calculated after adjusting for infants' gender, parents' age, maternal obstetrical history, gestational age, and birth weight. An increasing trend in social inequalities in all-cause infant mortality according to paternal education was evident. Social inequalities in infant mortality were greater for "Not classified symptoms, signs and findings" (International Classification of Diseases 10th revision [ICD-10]: R00-R99) and "Injury, poisoning and of external causes" (S00-T98), particularly for "Ill-defined and unspecified causes" (R990) and "Sudden infant death syndrome (SIDS)" (R950); and increased overtime for "Not classified symptoms, signs and findings" (R00-R99), "Injury, poisoning and of external causes" (S00-T98) and "Conditions in perinatal period" (P00-P96), particularly for "SIDS" (R950) and "Respiratory distress syndrome of newborns (RDS)" (P220). The specific causes of infant mortality, in particular the "Not classified causes" (R00-R99 coded deaths) should be investigated more thoroughly to reduce inequality in health. © 2017 The Korean Academy of Medical Sciences.

  4. Trends in Antiparkinsonian Medication Use in New Zealand: 1995–2011

    Directory of Open Access Journals (Sweden)

    T. L. Pitcher

    2014-01-01

    Full Text Available Prescribing trends for medications are influenced by development of new drugs, changes in knowledge about efficacy and side effects, and priorities set by funding agencies. Changes in the utilization of antiparkinsonian agents in the outpatient community in New Zealand were investigated by using the national prescription database for the period 1995–2011. The dispensed volumes of antiparkinsonian agents were converted into number of defined daily doses per 1000 inhabitants per day for analysis. Increases in the dispensed volumes of levodopa (77%, amantadine (350%, and catechol-o-methyl transferase inhibitors (326% occurred during the study period. Conversely, decreases in the dispensed volumes of anticholinergics (48%, selegiline (82%, and dopamine agonists (6.2% were observed. New Zealand has seen a substantial increase of the amount of levodopa dispensed in the past 17 years. This increase appears to be related to an increase in the number of people taking the medication. We are unable to extrapolate this change to an increase in the prevalence of PD, given levodopa is used in the treatment of a number of medical conditions. The changes in other antiparkinsonian medications largely reflect changes in availability (increases in entacapone and ropinirole and best practice treatment (declines in anticholinergics, selegiline, and tolcapone.

  5. Research and Recovery of Snake River Sockeye Salmon, 1995-1996 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Pravecek, Jay J.

    1997-07-01

    In 1991, the National Marine Fisheries Service listed Snake River sockeye salmon Oncorhynchus nerka as endangered under the Endangered Species Act of 1973. Initial steps to recover the species include the establishment of captive broodstocks at the Idaho Department of Fish and Game`s Eagle Fish Hatchery in Eagle, Idaho. Research and recovery activities for sockeye conducted by the Idaho Department of Fish and Game at the Eagle Fish Hatchery during the period April 1, 1995 to April 1, 1996 are covered by this report. The performance of all captive broodstock groups held at Eagle Fish Hatchery is included in this report. No anadromous adults returned to Redfish Lake in 1995. Three adult residual males were captured in a merwin trap and used in the spawning of captive residual females held at Eagle Fish Hatchery.

  6. Trends in Cancer Mortality Among Adolescents and Young Adults in Brazil.

    Science.gov (United States)

    Balmant, Nathalie Vieira; de Souza Reis, Rejane; de Oliveira Santos, Marceli; Pinto Oliveira, Julio; de Camargo, Beatriz

    2017-06-01

    Adolescents and young adults (AYA) with cancer comprise an intermediate age group between pediatric and adult oncology, and have a spectrum of different types of cancers. Survival among this group has not improved as much as in younger children with cancer. The aim of this study was evaluate the trends in cancer mortality of AYA aged 15-29 years in Brazil. Data were extracted from the Atlas of Cancer Mortality databases from 1979 to 2013. Age-specific mortality rates were calculated based on the deaths from each type of cancer and the period via a direct method using the proposed world population age groups. To identify significant changes in the trends, we performed joinpoint regression analysis. The mortality rates per million were 54 deaths in those aged 15-19 years, 61 deaths in those aged 20-24 years, and 88 deaths in those aged 25-29 years. Leukemias, lymphomas, and central nervous system (CNS) tumors occurred at high rates in all age groups. Rates of cervical cancer were highest in those aged 25-29 years. There were significant increases in mortality trends in the North and Northeast regions for all tumor groups, especially CNS tumors. A small decrease in the mortality rate from lymphomas was observed in the South and Southeast regions. Mortality in Brazilian AYA was slightly higher than in other studies conducted throughout the world. When separated by tumor type, Brazil presents a specific pattern, with high mortality from cervical cancer.

  7. Medico-legal claims against English radiologists: 1995–2006

    Science.gov (United States)

    Halpin, S F S

    2009-01-01

    A list of claims against radiologists from 1995–2006 was obtained from the NHS Litigation Authority. It shows a total of 440 claims. The largest number of claims (199) related to delayed or missed diagnoses of cancer, and 73 claims related to breast radiology. There is a trend for a mild increase in the number of claims each year. 30 claims were made after a false-positive diagnosis of cancer. Just under £8.5 million has so far been paid in damages, with a further £5 million in legal fees. A claim for multiple missed diagnoses of breast cancer led to a pay-out of £464 000 (£673 000 after legal fees); the largest sum awarded following a delay in the diagnosis of an individual cancer was £300 000. The subtle legal distinction between error and negligence is reviewed here. The reason why breast radiologists are more likely to be sued than any other type of British radiologist is also discussed, along with the implications for UK radiological practice, particularly in light of the recent Chief Medical Officer's report on revalidation. A method is proposed that may protect radiologists from allegations of clinical negligence in the future. PMID:19470570

  8. Trends in adherence to recommended cancer screening: The US population and working cancer survivors

    Directory of Open Access Journals (Sweden)

    Tainya C. Clarke

    2012-12-01

    Full Text Available Introduction: Over the past decade the United States has seen a decrease in advanced cancer diagnoses. There has also been an increase in the number of cancer survivors returning to work. Cancer screening behaviors among survivors may play an important role in their return-to-work process. Adherence to a post-treatment cancer screening protocol increases early detection of secondary tumors and reduces potentially limiting side-effects. We compared screening trends among all cancer survivors, working survivors, and the general population over the last decade.Methods: Trends in adherence to recommended screening were analyzed by site-specific cancer. We used the Healthy People goals as a measure of desired adherence. We selected participants 18+ years from 1997 to 2010 National Health Interview Survey (NHIS for years where detailed cancer screening information was available. Using the recommendations of the American Cancer Society as a guide, we assessed adherence to cancer screening across the decade. There were 174,393 participants. Analyses included 7,528 working cancer survivors representing 3.8 million US workers, and 119,374 adults representing more than 100 million working Americans with no cancer history.Results: The US population met the Healthy People 2010 goal for colorectal screening, but declined in all other recommended cancer screening. Cancer survivors met and maintained the HP2010 goal for all, except cervical cancer screening. Survivors had higher screening rates than the general population. Among survivors, white-collar and service occupations had higher screening rates than blue-collar survivors.Conclusions: Cancer survivors report higher screening rates than the general population. Nevertheless, national screening rates are lower than desired, and disparities exist by cancer history and occupation. Understanding existing disparities, and the impact of cancer screening on survivors is crucial as the number of working survivors

  9. Trends in Incidence and Factors Affecting Survival of Patients With Cholangiocarcinoma in the United States.

    Science.gov (United States)

    Mukkamalla, Shiva Kumar R; Naseri, Hussain M; Kim, Byung M; Katz, Steven C; Armenio, Vincent A

    2018-04-01

    Background: Cholangiocarcinoma (CCA) includes cancers arising from the intrahepatic and extrahepatic bile ducts. The etiology and pathogenesis of CCA remain poorly understood. This is the first study investigating both incidence patterns of CCA from 1973 through 2012 and demographic, clinical, and treatment variables affecting survival of patients with CCA. Patients and Methods: Using the SEER database, age-adjusted incidence rates were evaluated from 1973-2012 using SEER*Stat software. A retrospective cohort of 26,994 patients diagnosed with CCA from 1973-2008 was identified for survival analysis. Cox proportional hazards models were used to perform multivariate survival analysis. Results: Overall incidence of CCA increased by 65% from 1973-2012. Extrahepatic CCA (ECC) remained more common than intrahepatic CCA (ICC), whereas the incidence rates for ICC increased by 350% compared with a 20% increase seen with ECC. Men belonging to non-African American and non-Caucasian ethnicities had the highest incidence rates of CCA. This trend persisted throughout the study period, although African Americans and Caucasians saw 50% and 59% increases in incidence rates, respectively, compared with a 9% increase among other races. Median overall survival (OS) was 8 months in patients with ECC compared with 4 months in those with ICC. Our survival analysis found Hispanic women to have the best 5-year survival outcome ( P better survival outcomes compared with ICC ( P better survival outcomes compared with others ( P <.0001). Conclusions: This is the most up-to-date study of CCA from the SEER registry that shows temporal patterns of increasing incidence of CCA across different races, sexes, and ethnicities. We identified age, sex, race, marital status, income, smoking status, anatomic location of CCA, tumor grade, tumor stage, radiation, and surgery as independent prognostic factors for OS in patients with CCA. Copyright © 2018 by the National Comprehensive Cancer Network.

  10. Age-Specific Trends in Incidence, Mortality, and Comorbidities of Heart Failure in Denmark, 1995 to 2012

    DEFF Research Database (Denmark)

    Christiansen, Mia N.; Køber, Lars; Weeke, Peter

    2017-01-01

    on additional adjustment for diabetes mellitus, ischemic heart disease, and hypertension. Standardized 1-year mortality rates declined for middle-aged patients with heart failure but remained constant for younger (...Background: The cumulative burden and importance of cardiovascular risk factors have changed over the past decades. Specifically, obesity rates have increased among younger people, whereas cardiovascular health has improved in the elderly. Little is known regarding how these changes have impacted...... the incidence and the mortality rates of heart failure. Therefore, we aimed to investigate the age-specific trends in the incidence and 1-year mortality rates following a first-time diagnosis of heart failure in Denmark between 1995 and 2012. Methods: We included all Danish individuals >18 years of age...

  11. The utility of Google Trends data to examine interest in cancer screening.

    Science.gov (United States)

    Schootman, M; Toor, A; Cavazos-Rehg, P; Jeffe, D B; McQueen, A; Eberth, J; Davidson, N O

    2015-06-08

    We examined the utility of January 2004 to April 2014 Google Trends data from information searches for cancer screenings and preparations as a complement to population screening data, which are traditionally estimated through costly population-level surveys. State-level data across the USA. Persons who searched for terms related to cancer screening using Google, and persons who participated in the Behavioral Risk Factor Surveillance System (BRFSS). (1) State-level Google Trends data, providing relative search volume (RSV) data scaled to the highest search proportion per week (RSV100) for search terms over time since 2004 and across different geographical locations. (2) RSV of new screening tests, free/low-cost screening for breast and colorectal cancer, and new preparations for colonoscopy (Prepopik). (3) State-level breast, cervical, colorectal and prostate cancer screening rates. Correlations between Google Trends and BRFSS data ranged from 0.55 for ever having had a colonoscopy to 0.14 for having a Pap smear within the past 3 years. Free/low-cost mammography and colonoscopy showed higher RSV during their respective cancer awareness months. RSV for Miralax remained stable, while interest in Prepopik increased over time. RSV for lung cancer screening, virtual colonoscopy and three-dimensional mammography was low. Google Trends data provides enormous scientific possibilities, but are not a suitable substitute for, but may complement, traditional data collection and analysis about cancer screening and related interests. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  12. The epidemiological and histological trend of bladder cancer in Iran

    Directory of Open Access Journals (Sweden)

    Hosein Rafiemanesh

    2018-01-01

    Conclusion: According to this study the trend of ASIR of bladder cancer in Iran is rising, so it is necessary to conduct further researches in future to provide accurate information on the cancer and investigate related risk factors and implement prevention programs in Iran.

  13. Changing Trends in Gastric Cancer Surgery

    Directory of Open Access Journals (Sweden)

    İlter Özer

    2017-02-01

    Full Text Available Gastric cancer is one of the most common causes of cancer-related death. It requires multimodal treatment and surgery is the most effective treatment modality. Radical surgery includes total or subtotal gastrectomy with lymph node dissection. The extent of lymphadenectomy still remains controversial. Eastern surgeons have performed D2 or more extended lymphadenectomy while their Western colleagues have performed more limited lymph node dissection. However, the trend has been changing in favour of D2 lymph node dissection in both hemispheres. Currently, D2 is the recommended type of lymphadenectomy in experienced centres in the west. In Japan, D2 lymph node dissection is the standard surgical approach. More extensive lymphadenectomy than D2 has not been found to be associated with improved survival and generally is not performed. Bursectomy and splenectomy are additional controversial issues in surgical performance, and trends regarding them will be discussed. The performance of bursectomy is controversial and there is no clear evidence of its clinical benefit. However, a trend toward better survival in patients with serosal invasion has been reported. Routine splenectomy as a part of lymph node dissection has largely been abandoned, although splenectomy is recommended in selected cases. Minimally invasive surgery has gained wide popularity and indications for minimally invasive procedures have been expanding due to increasing experience and improving technology. Neoadjuvant therapy has been shown to have beneficial effects and seems necessary to provide a survival benefit. Diagnostic laparoscopy should be kept in mind prior to treatment

  14. Bladder cancer mortality trends and patterns in Córdoba, Argentina (1986-2006).

    Science.gov (United States)

    Pou, Sonia Alejandra; Osella, Alberto Ruben; Diaz, Maria Del Pilar

    2011-03-01

    Bladder cancer is common worldwide and the fourth most commonly diagnosed malignancy in men in Argentina. To describe bladder cancer mortality trends in Córdoba (1986-2006), considering the effect of age, period, and cohort, and to estimate the effect of arsenic exposure on bladder cancer, and its interaction with sex, while controlling by smoking habits and space and time variation of the rates. A joinpoint regression was performed to compute the estimated annual percentage changes (EAPC) of the age-standardized mortality rates (ASMR) in an adult population from Córdoba, Argentina. A Poisson model was fitted to estimate the effect of age, period, and cohort. The influence of gender, tobacco smoking (using lung cancer ASMR as surrogate), and arsenic in drinking water was examined using a hierarchical model. A favorable trend (1986-2006) in bladder cancer ASMR in both sexes was found: EAPC of -2.54 in men and -1.69 in women. There was a decreasing trend in relative risk (RR) for cohorts born in 1931 or after. The multilevel model showed an increasing risk for each increase in lung cancer ASMR unit (RR = 1.001) and a biological interaction between sex and arsenic exposure. RR was higher among men exposed to increasing As-exposure categories (RR male low exposure 3.14, RR male intermediate exposure 4.03, RR male high exposure 4.71 versus female low exposure). A non-random space-time distribution of the rates was observed. There has been a decreasing trend in ASMR for bladder cancer in Córdoba. This study confirms that bladder cancer is associated with age, gender, smoking habit, and exposure to arsenic. Moreover, an effect measure modification between exposure to arsenic and sex was found.

  15. Trends between 1973 and 1988: Summary and key issues

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    The preceding chapters considered the evolution of activity, structure, energy intensity, and energy use between the early 1970s and 1988 for the manufacturing, transportation, residential, and service sectors. In this chapter, the author summarizes the changes that have taken place, and presents results of a cross-sectoral analysis of the effect of change in sectoral activity, structure, and energy intensity on energy use in the three largest OECD economies: the United States, Japan, and West Germany. He also addresses a number of key issues that have important implications for future energy use in the OECD countries and elsewhere. Between 1973 and 1988, final energy use in the five sectors studied (which account for around 90% of total energy use) grew by 3% in the United, States, 15% in Japan, and 3% in West Germany. Energy use in manufacturing declined by 10-20% in each country. Energy use for passenger travel grew by only 11% in the United States, but rose by 76% in Japan and by 56% in West Germany. There was moderate to strong growth in freight energy use in all three countries. There was very high growth in residential and services energy use in Japan, and moderate growth in these sectors in the United States and West Germany. 12 refs., 5 figs., 3 tabs

  16. Tendência de mortalidade do câncer de pulmão, traquéia e brônquios no Brasil, 1980-2003 Lung cancer, cancer of the trachea, and bronchial cancer: mortality trends in Brazil, 1980-2003

    Directory of Open Access Journals (Sweden)

    Deborah Carvalho Malta

    2007-10-01

    Full Text Available OBJETIVO: Descrever a tendência da mortalidade do câncer de pulmão, traquéia e brônquios por sexo e faixas etárias no Brasil. MÉTODOS: Para essa análise, utilizou-se o banco de dados do Sistema de Informações sobre Mortalidade de 1980 a 2003. A análise de tendência de mortalidade no Brasil e em estados selecionados foi realizada com o ajuste de modelos e utilização da técnica LOWESS para suavização das taxas. RESULTADOS: No Brasil, a taxa padronizada de mortalidade por câncer de pulmão, traquéia e brônquios passou de 7,21 em 1980 a 9,36 óbitos por 100 mil habitantes em 2003. A análise das taxas de mortalidade específicas mostra redução em homens entre 30 e 49 anos e entre 50 e 59 anos. Entre os homens de 60 a 69 anos ocorreu aumento das taxas entre 1980 até 1995, seguido de declínio. Entre homens acima de 70 anos e entre mulheres em todas as faixas etárias acima de 30 anos, a tendência é de aumento das taxas em todo o período analisado. CONCLUSÕES: a redução das taxas de mortalidade entre homens mais jovens pode ser o resultado das ações nacionais para a redução da prevalência do tabagismo no país nas décadas mais recentes, reduzindo a exposição nas coortes mais jovens. A manutenção de taxas elevadas de mortalidade em populações mais idosas deve-se a experiência do tabagismo passado. Quanto às mulheres, a elevação das taxas segue tendência mundial, também em função do aumento da prevalência do tabagismo entre mulheres nos anos recentes.OBJECTIVE: To describe the mortality trends for lung cancer, cancer of the trachea, and bronchial cancer in relation to gender and age brackets in Brazil. METHODS: Data related to mortality between 1980 and 2003 were collected from the Brazilian Mortality Database. A trend analysis of mortality was carried out, nationwide and in selected states, using the LOWESS technique for rate smoothing and model adjustments. RESULTS: In Brazil, the standardized

  17. Ship operations report, 1973

    International Nuclear Information System (INIS)

    1973-01-01

    The NOAA Fleet Operations Report 1973 was developed to provide a summary of project accomplishments during calendar year 1973. The report was prepared from season, cruise and special reports submitted by ships of the fleet. Centralized management of the NOAA Fleet was finalized by changing the operational control of the National Marine Fisheries Service (NMFS) Ships DAVID STARR JORDAN (FRS 44), TOWNSEND CROMWELL (FRS 43) and MURRE II (FRV 63) from NMFS to the National Ocean Survey on July 1, 1973. Throughout the year, ships routinely collected and transmitted weather data. Similarly, as NOAA participants in the Integrated Global Ocean Station System (IGOSS) service program, XBT observations were taken and either radioed or submitted in log form via mail. In addition, particulate and radionuclide samples were taken in cooperation with the Atomic Energy Commission, sediment samples were obtained for the Smithsonian Institution and observations were made of marine mammals

  18. Cancer incidence in Canada: trends and projections (1983-2032

    Directory of Open Access Journals (Sweden)

    Lin Xie

    2015-01-01

    liver cancer and leukemia in both sexes. In contrast, this region is projected to experience elevated incidence rates in males for about half the cancers studied. The incidence rates for all cancers combined are projected to continue to be highest for males in the Atlantic region and for females in Quebec in 15 years but in Ontario thereafter, and lowest in British Columbia. The inter-regional differences are larger in males than in females, possibly due to variations in prostate-specific antigen (PSA testing (for prostate cancer and risk factors. In both males and females, colorectal cancer incidence rates will remain highest in the Atlantic region and lowest in British Columbia. Lung cancer incidence rates are projected to be highest in Quebec and lowest in Ontario and British Columbia for both sexes. The similar regional rates of breast cancer in females are expected to persist. The significantly lowest rates of prostate cancer in Quebec are projected to continue, as are the elevated rates in the Atlantic region. Incidence by sex and age: Cancer is more common in males than in females except in those aged under 55. The overall cancer incidence rate in men aged 65 or older has been falling and will continue to do so. The decrease in lung cancer rates in men aged 65 or older from decreased tobacco use and the decrease in prostate cancer rates in men aged 75 or older have contributed to the overall decrease in this age range. In women aged 65 or older, the relatively stable rate is primarily the result of an increase in lung cancer incidence offset by decreases in incidence for the other cancer sites. This stable trend is projected to continue. Targeted cancer prevention efforts and specific needs for health care services can be expected to vary at different points in the age continuum for males and females. Smoking-related cancers: Between 2003-2007 and 2028-2032, substantial risk reductions are projected for major common tobacco-related cancers in Canada, even with

  19. Trend Analysis of Betel Nut-associated Oral Cancer 
and Health Burden in China.

    Science.gov (United States)

    Hu, Yan Jia; Chen, Jie; Zhong, Wai Sheng; Ling, Tian You; Jian, Xin Chun; Lu, Ruo Huang; Tang, Zhan Gui; Tao, Lin

    To forecast the future trend of betel nut-associated oral cancer and the resulting burden on health based on historical oral cancer patient data in Hunan province, China. Oral cancer patient data in five hospitals in Changsha (the capital city of Hunan province) were collected for the past 12 years. Three methods were used to analyse the data; Microsoft Excel Forecast Sheet, Excel Trendline, and the Logistic growth model. A combination of these three methods was used to forecast the future trend of betel nut-associated oral cancer and the resulting burden on health. Betel nut-associated oral cancer cases have been increasing rapidly in the past 12  years in Changsha. As of 2016, betel nuts had caused 8,222 cases of oral cancer in Changsha and close to 25,000 cases in Hunan, resulting in about ¥5 billion in accumulated financial loss. The combined trend analysis predicts that by 2030, betel nuts will cause more than 100,000 cases of oral cancer in Changsha and more than 300,000 cases in Hunan, and more than ¥64 billion in accumulated financial loss in medical expenses. The trend analysis of oral cancer patient data predicts that the growing betel nut industry in Hunan province will cause a humanitarian catastrophe with massive loss of human life and national resources. To prevent this catastrophe, China should ban betel nuts and provide early oral cancer screening for betel nut consumers as soon as possible.

  20. Idaho Habitat/Natural Production Monitoring Part I, 1995 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Hall-Griswold, J.A.; Petrosky, C.E. (Idaho Department of Fish and Game, Boise, ID)

    1996-12-01

    The Idaho Department of Fish and Game (IDFG) has been monitoring trends in juvenile spring and summer chinook salmon, Oncorhynchus tshawytscha, and steelhead trout, O. mykiss, populations in the Salmon, Clearwater, and lower Snake River drainages for the past 12 years. This work is the result of a program to protect, mitigate, and enhance fish and wildlife affected by the development and operation of hydroelectric power plants on the Columbia River. Project 91-73, Idaho Natural Production Monitoring, consists of two subprojects: General Monitoring and Intensive Monitoring. This report updates and summarizes data through 1995 for the General Parr Monitoring (GPM) database to document status and trends of classes of wild and natural chinook salmon and steelhead trout populations. A total of 281 stream sections were sampled in 1995 to monitor trends in spring and summer chinook salmon Oncorhynchus tshawytscha and steelhead trout O. mykiss parr populations in Idaho. Percent carrying capacity and density estimates were summarized for 1985--1995 by different classes of fish: wild A-run steelhead trout, wild B-run steelhead trout, natural A-run steelhead trout, natural B-run steelhead trout, wild spring and summer chinook salmon, and natural spring and summer chinook salmon. The 1995 data were also summarized by subbasins as defined in Idaho Department of Fish and Game`s 1992--1996 Anadromous Fish Management Plan.

  1. Idaho habitat/natural production monitoring: Part 1. Annual report 1995

    International Nuclear Information System (INIS)

    Hall-Griswold, J.A.; Petrosky, C.E.

    1996-11-01

    The Idaho Department of Fish and Game (IDFG) has been monitoring trends in juvenile spring and summer chinook salmon, Oncorhynchus tshawytscha, and steelhead trout, O. mykiss, populations in the Salmon, Clearwater, and lower Snake River drainages for the past 12 years. This work is the result of a program to protect, mitigate, and enhance fish and wildlife affected by the development and operation of hydroelectric power plants on the Columbia River. Project 91-73, Idaho Natural Production Monitoring, consists of two subprojects: General Monitoring and Intensive Monitoring. This report updates and summarizes data through 1995 for the General Parr Monitoring (GPM) database to document status and trends of classes of wild and natural chinook salmon and steelhead trout populations. A total of 281 stream sections were sampled in 1995 to monitor trends in spring and summer chinook salmon Oncorhynchus tshawytscha and steelhead trout O. mykiss parr populations in Idaho. Percent carrying capacity and density estimates were summarized for 1985--1995 by different classes of fish: wild A-run steelhead trout, wild B-run steelhead trout, natural A-run steelhead trout, natural B-run steelhead trout, wild spring and summer chinook salmon, and natural spring and summer chinook salmon. The 1995 data were also summarized by subbasins as defined in Idaho Department of Fish and Game's 1992--1996 Anadromous Fish Management Plan

  2. Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2).

    Science.gov (United States)

    Allemani, Claudia; Weir, Hannah K; Carreira, Helena; Harewood, Rhea; Spika, Devon; Wang, Xiao-Si; Bannon, Finian; Ahn, Jane V; Johnson, Christopher J; Bonaventure, Audrey; Marcos-Gragera, Rafael; Stiller, Charles; Azevedo e Silva, Gulnar; Chen, Wan-Qing; Ogunbiyi, Olufemi J; Rachet, Bernard; Soeberg, Matthew J; You, Hui; Matsuda, Tomohiro; Bielska-Lasota, Magdalena; Storm, Hans; Tucker, Thomas C; Coleman, Michel P

    2015-03-14

    than 50% to more than 70%; regional variations are much wider, and improvements between 1995-99 and 2005-09 have generally been slight. For women diagnosed with ovarian cancer in 2005-09, 5-year survival was 40% or higher only in Ecuador, the USA, and 17 countries in Asia and Europe. 5-year survival for stomach cancer in 2005-09 was high (54-58%) in Japan and South Korea, compared with less than 40% in other countries. By contrast, 5-year survival from adult leukaemia in Japan and South Korea (18-23%) is lower than in most other countries. 5-year survival from childhood acute lymphoblastic leukaemia is less than 60% in several countries, but as high as 90% in Canada and four European countries, which suggests major deficiencies in the management of a largely curable disease. International comparison of survival trends reveals very wide differences that are likely to be attributable to differences in access to early diagnosis and optimum treatment. Continuous worldwide surveillance of cancer survival should become an indispensable source of information for cancer patients and researchers and a stimulus for politicians to improve health policy and health-care systems. Canadian Partnership Against Cancer (Toronto, Canada), Cancer Focus Northern Ireland (Belfast, UK), Cancer Institute New South Wales (Sydney, Australia), Cancer Research UK (London, UK), Centers for Disease Control and Prevention (Atlanta, GA, USA), Swiss Re (London, UK), Swiss Cancer Research foundation (Bern, Switzerland), Swiss Cancer League (Bern, Switzerland), and University of Kentucky (Lexington, KY, USA). Copyright © 2015 Allemani et al. Open Access article distributed under the terms of CC BY. Published by Elsevier Ltd. All rights reserved.

  3. Cancer communication science funding trends, 2000-2012.

    Science.gov (United States)

    Ramírez, A Susana; Galica, Kasia; Blake, Kelly D; Chou, Wen-Ying Sylvia; Hesse, Bradford W

    2013-12-01

    Since 2000, the field of health communication has grown tremendously, owing largely to research funding by the National Cancer Institute (NCI). This study provides an overview of cancer communication science funding trends in the past decade. We conducted an analysis of communication-related grant applications submitted to the NCI in fiscal years 2000-2012. Using 103 keywords related to health communication, data were extracted from the Portfolio Management Application, a grants management application used at NCI. Automated coding described key grant characteristics such as mechanism and review study section. Manual coding determined funding across the cancer control continuum, by cancer site, and by cancer risk factors. A total of 3307 unique grant applications met initial inclusion criteria; 1013 of these were funded over the 12-year period. The top funded grant mechanisms were the R01, R21, and R03. Applications were largely investigator-initiated proposals as opposed to responses to particular funding opportunity announcements. Among funded communication research, the top risk factor being studied was tobacco, and across the cancer control continuum, cancer prevention was the most common stage investigated. NCI support of cancer communication research has been an important source of growth for health communication science over the last 12 years. The analysis' findings describe NCI's priorities in cancer communication science and suggest areas for future investments.

  4. The influence of death-certificate errors on cancer mortality trends

    International Nuclear Information System (INIS)

    Ron, E.; Hoel, D.G.; Carter, R.L.; Mabuchi, Kiyohiko.

    1993-06-01

    Over the past few years, several reports have suggested a recent increase in cancer mortality based on death-certificate diagnoses. To explore the effect of death-certificate errors on temporal trends in cancer mortality rates, we analyzed the data from the Atomic Bomb Casualty Commission/Radiation Effects Research Foundation's autopsy program in Hiroshima and Nagasaki. This series includes 5886 autopsies conducted between 1961 and 1987. Our analyses were focused on lymphoma, cancer of the breast, neoplasms of the brain, multiple myeloma, and melanoma (172 cases, total) because of concern over reports of their increased mortality. These 172 autopsy cases were referred to as Cancers of Interest. A significant increase in detection rates was observed for these Cancers of Interest primarily due to a large rise in mortality between 1976 and 1987. For the remaining cancers excluding stomach and lung (defined as Other), the pattern was similar to that seen for Cancers of Interest, but the fluctuation over time was not statistically significant. Confirmation rates generally increased with time except for Cancers of Interest. As a measure of bias in mortality rates due to death-certification errors and as a method to quantify under- or overestimation of death-certificate-based mortality rates,an adjustment factor (confirmation rate divided by detection rate) was calculated. The higher the adjustment factor, the greater the need to compensate for underreporting. For Cancers of Interest the adjustment factor decreased dramatically over time, but it did not change significantly for Other cancers. When the adjustment factors for Cancers of Interest and Other were compared, a statistically significant difference was found. For Cancers of Interest, a significant interaction between type of cancer and period was seen. Our findings indicate that considerable care must be shown when interpreting temporal trends in cancer vital statistics. (author)

  5. Coal information 1995

    International Nuclear Information System (INIS)

    1996-01-01

    This volume is a comprehensive reference book on current world coal market trends and long-term prospects to 2010. It contains an in-depth analysis of the 1995 international coal market covering prices, demand, trade, supply and production capacity as well as over 450 pages of country specific statistics on OECD and key non-OECD coal producing and consuming countries. The book also includes a summary of environmental policies on climate change and on coal-related air quality issues as well as essential facts on coal-fired power stations in coal-importing regions, on coal ports world-wide and on emission standards for coal-fired boilers in OECD countries. Coal Information is one of a series of annual IEA statistical publications on major energy sources; other reports are Oil and Gas Information and Electricity Information. Coal Information 1995 is published in July 1996. (author)

  6. An analysis of cancer death risk among medical diagnostic X-ray workers in China, 1950-1995

    International Nuclear Information System (INIS)

    Zhao Yongcheng; Wang Jixian; Zhang Wei; Li Benxiao; Fan Tiqiang; Zhang Jingyuan

    2002-01-01

    Objective: To investigate effects of occupational radiation exposure on cancer death among medical diagnostic X-ray workers. Methods: A cohort study on medical diagnostic X-ray workers and non-X-ray medical workers was carried out and a risk analysis of cancer death between 1950 and 1995 was conducted with the O/E system. Results: A significant enhancement in cancer death risk for X-ray workers was found, especially those engaged in X-ray work in early calendar years. The overall cancer RR was 1.26, (95 % CI: 1.14 - 1.38), for leukemia it was 2.48, (95% CI: 1.68-3.51 ); for esophagus cancer, 3.18, (95% CI: 2.02 -4.77); for liver cancer, 1.54, (95 % CI: 1.27 - 1.86); and for bone cancer, 2.48, (95 % CI: 1.00 - 5.40). In the late calendar year cohort a significant enhancement of cancer death was seen only in esophagus cancer (RR = 4.19, 95 % CI: 1.80 - 8.25) and lung cancer (RR = 1.60, 95% CI:1.10-2.25). Conclusion: Long-term occupational X-ray irradiation can enhance the risk of cancer death when the cumulative dose reached a certain level. The significant enhancement of cancer death for leukemia and some solid cancers may be related to the occupational exposure to X-rays

  7. Trends in intensity modulated radiation therapy use for locally advanced rectal cancer at National Comprehensive Cancer Network centers

    OpenAIRE

    Marsha Reyngold, MD, PhD; Joyce Niland, PhD; Anna ter Veer, MS; Tanios Bekaii-Saab, MD; Lily Lai, MD; Joshua E. Meyer, MD; Steven J. Nurkin, MD, MS; Deborah Schrag, MD, MPH; John M. Skibber, MD, FACS; Al B. Benson, MD; Martin R. Weiser, MD; Christopher H. Crane, MD; Karyn A. Goodman, MD, MS

    2018-01-01

    Purpose: Intensity modulated radiation therapy (IMRT) has been rapidly incorporated into clinical practice because of its technological advantages over 3-dimensional conformal radiation therapy (CRT). We characterized trends in IMRT utilization in trimodality treatment of locally advanced rectal cancer at National Comprehensive Cancer Network cancer centers between 2005 and 2011. Methods and materials: Using the prospective National Comprehensive Cancer Network Colorectal Cancer Database, ...

  8. Development and economic trends in cancer therapeutic drugs: a 5-year update 2010-2014.

    Science.gov (United States)

    Savage, P; Mahmoud, S

    2015-03-17

    Over the past 20 years, the mechanisms of action, duration of benefits and economic costs of newly licenced cancer drugs have changed significantly; however, summary data on these characteristics are limited. In this study, using historical copies of the British National Formulary and relevant contemporary publications, we have documented for each new cancer drug the year of introduction, therapeutic classification, initial indication, median duration of treatment and the cost of treatment at introduction relative to the then current UK GDP per capita. Before 2000, there were 69 cancer treatment drugs available, of which 50 (72.5%) were classical cytotoxic drugs. In the subsequent 15 years, there have been 63 more new cancer treatment drugs added, including 20 kinase inhibitors and 11 monoclonal antibodies. The average median duration of treatment with a new drug has risen from 181 days in 1995-1999 to 263 days in 2010-2014. The average cost of treatment has also risen from £3036.91 (20.6% of UK per capita GDP) in 1995-1999 to £20 233 (89.0%) in 2005-2009 and now to £35 383 (141.7%) in 2010-2014. The last 5 years has seen 33 new cancer drugs. These drugs deliver significant benefits in patient outcomes and are taken for increasing lengths of time. Alongside these clinical benefits, the direct costs of new treatments have increased significantly over the past decade.

  9. Patterns of breast cancer mortality trends in Europe.

    Science.gov (United States)

    Amaro, Joana; Severo, Milton; Vilela, Sofia; Fonseca, Sérgio; Fontes, Filipa; La Vecchia, Carlo; Lunet, Nuno

    2013-06-01

    To identify patterns of variation in breast cancer mortality in Europe (1980-2010), using a model-based approach. Mortality data were obtained from the World Health Organization database and mixed models were used to describe the time trends in the age-standardized mortality rates (ASMR). Model-based clustering was used to identify clusters of countries with homogeneous variation in ASMR. Three patterns were identified. Patterns 1 and 2 are characterized by stable or slightly increasing trends in ASMR in the first half of the period analysed, and a clear decline is observed thereafter; in pattern 1 the median of the ASMR is higher, and the highest rates were achieved sooner. Pattern 3 is characterised by a rapid increase in mortality until 1999, declining slowly thereafter. This study provides a general model for the description and interpretation of the variation in breast cancer mortality in Europe, based in three main patterns. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Panorama of mining activities in France during 1995

    International Nuclear Information System (INIS)

    Michel, J.C.; Bornuat, M.; Mouron, R.

    1996-01-01

    The French mining industry in 1995 continued to follow the overall trend of the past 5 to 10 years characterized mainly by: 1)a decline in the production of most energy materials: oil, coal, uranium. This decline will probably be further accentuated over the next two years with the planned closure of Lodeve (U), Forbach, La Mure and Carmaux (coal). Gas production, however, has remained relatively stable at 4.7 to 5 billion m''3 per year. 2)a scarcity of metal ore mines in Metropolitan France 3)an increase in the production of gold that, in 1995, came close to 6 tonnes in Metropolitan France and reached 8.4 tonnes with French Guiana. 4)the development of metal ore mining in the DOM-TOM 5) divergent developments in the industrial mineral sector: downward trends for sulfur, talc, andalusite, diatomite and silica; upward trends for kaolin, mica, feldspar and salt. Although overall the decline in mine production continued, the panorama does include some positive aspects: 1)France's independence in the energy sector exceeded the half-way mark two years ago and 1995 saw an appreciable decrease in the nation's energy bill compared to 1994. 2)French companies involved in metal mining have adapted themselves to world trends: Cogema has diversified its uranium sources mainly through its mining interests in Canada; Eramet has strengthened its activities by becoming the majority shareholder of Comilog, a manganese producer in Gabon. France also has mining interests in Africa, South America and Europe through LaSource Compagnie Miniere (BRGM and Normandy) created in 1995 3) France's position and production in the industrial mineral sector are significant at European scale, if not at world scale, as regards andalusite, diatomite, kaolin, mica, feldspar, sulfur, potassium, salt and industrial silica. Finally, mention must be made of the increasing environmental awareness by the French authorities and mining companies. This has resulted in a major rehabilitation of mine sites by

  11. A FEW COMMENTS ON TRENDS IN CONTEMPORARY NORWEGIAN FICTION AND ITS PRESENCE IN THE POLISH BOOK MARKET IN THE YEARS 1995–2010

    Directory of Open Access Journals (Sweden)

    Katarzyna Tunkiel

    2011-01-01

    Full Text Available After 1995, and especially since 2004, there has been an increase in the number of Norwegian fiction books published in Poland. The first part of the paper presents detailed statistical data for this trend and analyses it shortly. The second part is an attempt to introduce the most important trends in contemporary Norwegian literature and indicate how these are reflected in the offer in the Polish book market. The increased popularity of Norwegian fiction in Poland may be a result of the readers’ preferences, but on the other hand also of the general interest in Norway and, not less importantly, the availability of subsidies for literary translations. The books published in Poland in 1995–2010 reflect very well the most characteristic trends in contemporary Norwegian literature. One can find among them examples of both minimalism (including naivism and encyclopaedism, while the most typical subject areas include family relations, existential problems and religion. Biographies and autobiographies that recently have been a crucial and much-discussed group of literary production in Norway are less represented. The phenomenon of popular literature – the new heyday of the romantic novel series as well as the fashion for Scandinavian crime fiction – is also noteworthy. In addition, some valuable Norwegian books for children and youth were translated into Polish and published in the period. On the whole, it should be emphasised that the situation of Norwegian fiction in Poland is very good; it is undoubtedly one of the best represented minor European literatures in the Polish market.

  12. Trends in cardiovascular diseases and cancer mortality in 45 countries from five continents (1980-2010).

    Science.gov (United States)

    Araújo, Fábio; Gouvinhas, Cláudia; Fontes, Filipa; La Vecchia, Carlo; Azevedo, Ana; Lunet, Nuno

    2014-08-01

    Cardiovascular diseases (CVD) and cancer are worldwide main causes of death with mortality trends varying across countries with different levels of economic development. We analysed trends in CVD and cancer mortality for 37 European countries, five high-income non-European countries and four leading emerging economies (BRICS) using data from the World Health Organization database for the period 1980-2010. In high-income countries, CVD mortality trends are characterized by steep declines over the last decades, while a downward trend in cancer mortality started more recently and was less pronounced. This resulted in the gradual convergence of the CVD and cancer mortality rates, and the latter are already higher in some countries. The absolute number of CVD deaths decreased in most settings, while cancer deaths increased in nearly all countries. Among the BRICS, China and South Africa share a similar pattern of no meaningful variation in both CVD and cancer age-standardized mortality rates and an increase in the overall number of deaths by these causes. Brazil presents trends similar to those of high-income countries, except for the still increasing number of CVD deaths. The substantial decreases in CVD mortality over the last decades have overcome the impact of the growth and ageing of populations in the overall number of deaths, while stabilization in the number of cancer deaths was observed only in some of the high-income countries. © The European Society of Cardiology 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  13. Cancer burden trends in Umbria region using a joinpoint regression

    Directory of Open Access Journals (Sweden)

    Giuseppe Michele Masanotti

    2015-09-01

    Full Text Available INTRODUCTION. The analysis of the epidemiological data on cancer is an important tool to control and evaluate the outcomes of primary and secondary prevention, the effectiveness of health care and, in general, all cancer control activities. MATERIALS AND METHODS. The aim of the this paper is to analyze the cancer mortality in the Umbria region from 1978 to 2009 and incidence from 1994-2008. Sex and site-specific trends for standardized rates were analyzed by "joinpoint regression", using the surveillance epidemiology and end results (SEER software. RESULTS. Applying the jointpoint analyses by sex and cancer site, to incidence spanning from 1994 to 2008 and mortality from 1978 to 2009 for all sites, both in males and females, a significant joinpoint for mortality was found; moreover the trend shape was similar and the joinpoint years were very close. In males standardized rate significantly increased up to 1989 by 1.23% per year and significantly decreased thereafter by -1.31%; among females the mortality rate increased in average of 0.78% (not significant per year till 1988 and afterward significantly decreased by -0.92% per year. Incidence rate showed different trends among sexes. In males was practically constant over the period studied (not significant increase 0.14% per year, in females significantly increased by 1.49% per year up to 2001 and afterward slowly decreased (-0.71% n.s. estimated annual percent change − EAPC. CONCLUSIONS. For all sites combined trends for mortality decreased since late '80s, both in males and females; such behaviour is in line with national and European Union data. This work shows that, even compared to health systems that invest more resources, the Umbria public health system achieved good health outcomes.

  14. Status and trends of land change in the Eastern United States—1973 to 2000

    Science.gov (United States)

    Sayler, Kristi L.; Acevedo, William; Taylor, Janis

    2016-09-28

    PrefaceU.S. Geological Survey (USGS) Professional Paper 1794–D is the fourth in a four-volume series on the status and trends of the Nation’s land use and land cover, providing an assessment of the rates and causes of land-use and land-cover change in the Eastern United States between 1973 and 2000. Volumes A, B, and C provide similar analyses for the Western United States, the Great Plains of the United States, and the Midwest–South Central United States, respectively. The assessments of land-use and land-cover trends are conducted on an ecoregion-by-ecoregion basis, and each ecoregion assessment is guided by a nationally consistent study design that includes mapping, statistical methods, field studies, and analysis. Individual assessments provide a picture of the characteristics of land change occurring in a given ecoregion; in combination, they provide a framework for understanding the complex national mosaic of change and also the causes and consequences of change. Thus, each volume in this series provides a regional assessment of how (and how fast) land use and land cover are changing, and why. The four volumes together form the first comprehensive picture of land change across the Nation.Geographic understanding of land-use and land-cover change is directly relevant to a wide variety of stakeholders, including land and resource managers, policymakers, and scientists. The chapters in this volume present brief summaries of the patterns and rates of land change observed in each ecoregion in the Eastern United States, together with field photographs, statistics, and comparisons with other assessments. In addition, a synthesis chapter summarizes the scope of land change observed across the entire Eastern United States. The studies provide a way of integrating information across the landscape, and they form a critical component in the efforts to understand how land use and land cover affect important issues such as the provision of ecological goods and

  15. Trends in Female Breast Cancer by Age Group in the Chiang Mai Population

    Science.gov (United States)

    Sripan, Patumrat; Sriplung, Hutcha; Pongnikorn, Donsuk; Virani, Shama; Bilheem, Surichai; Chaisaengkhaum, Udomlak; Maneesai, Puttachart; Waisri, Narate; Hanpragopsuk, Chirapong; Tansiri, Panrada; Khamsan, Varunee; Poungsombat, Malisa; Mawoot, Aumnart; Chitapanarux, Imjai

    2017-01-01

    Objectives: This study was conducted to determine incidence trends of female breast cancer according to age groups and to predict future change in Chiang Mai women through 2028. Method: Data were collected from all hospitals in Chiang Mai in northern Thailand, from 1989 through 2013, and used to investigate effects of age, year of diagnosis (period) and year of birth (cohort) on female breast cancer incidences using an age-period-cohort model. This model features geometric cut trends to predict change by young (<40 years), middle-aged (40-59) and elderly (≥60) age groups. Result: Of 5, 417 female breast cancer patients with a median age of 50 years (interquartile range: 43 to 59 years), 15%, 61% and 24% were young, middle-aged and elderly, respectively. Seventy nine percent of cancer cases in this study were detected at advanced stage. The trend in stage classification showed an increase in percentage of early stage and a decrease in metastatic cancers. Linear trends for cohort and period were not found in young females but were observed in middle-aged and elderly groups. Age-standardized rates (ASR) can be expected to remain stable around 6.8 per 100,000 women-years in young females. In the other age groups, the ASR trends were calculated to increase and reach peaks in 2024 of 120.2 and 138.2 per 100,000 women-years, respectively. Conclusion: Cohort effects or generation-specific effects, such as life style factors and the year of diagnosis (period) might have impacted on increased incidence in women aged over 40 years but not those under 40 years. A budget should be provided for treatment facilities and strategies to detect early stage cancers. The cost effectiveness of screening measures i.e. mammographic screening may need to be reconsidered for women age over 40 years. PMID:28612595

  16. Global surveillance of cancer survival 1995–2009: analysis of individual data for 25 676 887 patients from 279 population-based registries in 67 countries (CONCORD-2)

    Science.gov (United States)

    Allemani, Claudia; Weir, Hannah K; Carreira, Helena; Harewood, Rhea; Spika, Devon; Wang, Xiao-Si; Bannon, Finian; Ahn, Jane V; Johnson, Christopher J; Bonaventure, Audrey; Marcos-Gragera, Rafael; Stiller, Charles; Silva, Gulnar Azevedo e; Chen, Wan-Qing; Ogunbiyi, Olufemi J; Rachet, Bernard; Soeberg, Matthew J; You, Hui; Matsuda, Tomohiro; Bielska-Lasota, Magdalena; Storm, Hans; Tucker, Thomas C; Coleman, Michel P

    2015-01-01

    , national estimates of 5-year survival range from less than 50% to more than 70%; regional variations are much wider, and improvements between 1995–99 and 2005–09 have generally been slight. For women diagnosed with ovarian cancer in 2005–09, 5-year survival was 40% or higher only in Ecuador, the USA, and 17 countries in Asia and Europe. 5-year survival for stomach cancer in 2005–09 was high (54–58%) in Japan and South Korea, compared with less than 40% in other countries. By contrast, 5-year survival from adult leukaemia in Japan and South Korea (18–23%) is lower than in most other countries. 5-year survival from childhood acute lymphoblastic leukaemia is less than 60% in several countries, but as high as 90% in Canada and four European countries, which suggests major deficiencies in the management of a largely curable disease. Interpretation International comparison of survival trends reveals very wide differences that are likely to be attributable to differences in access to early diagnosis and optimum treatment. Continuous worldwide surveillance of cancer survival should become an indispensable source of information for cancer patients and researchers and a stimulus for politicians to improve health policy and health-care systems. Funding Canadian Partnership Against Cancer (Toronto, Canada), Cancer Focus Northern Ireland (Belfast, UK), Cancer Institute New South Wales (Sydney, Australia), Cancer Research UK (London, UK), Centers for Disease Control and Prevention (Atlanta, GA, USA), Swiss Re (London, UK), Swiss Cancer Research foundation (Bern, Switzerland), Swiss Cancer League (Bern, Switzerland), and University of Kentucky (Lexington, KY, USA). PMID:25467588

  17. Effect of demographic factors on brachytherapy treatment results in patients with endometrial cancer 1995-2010.

    Science.gov (United States)

    Jurczyk, Mieczysława U; Chmaj-Wierzchowska, Karolina; Klofik, Joanna; Sajdak, Stefan; Opala, Tomasz

    2013-01-01

    Approximately 1 in 20 female cancers in Europe is of the endometrium. Endometrial carcinoma is the most common gynaecologic cancer. Considering the fact that an upward tendency has recently been observed in morbidity due to this type of cancer, this is a serious medical problem. The presented report describes the results of the analysis of selected demographic factors and their effect on the incidence of endometrial cancer. Analysis of the results of treatment of endometrial cancer during 1995-2010 was also an objective of the study. Based on medical records obtained from the HDR Laboratory of Brachytherapy at the Gynaecological & Obstetrics Clinical Hospital, University of Medical Sciences in Poznań, the results of treatment of patients with endometrial cancer by brachytherapy were analyzed. The analysis covered a group of 400 patients. More than a half of the patients completed their education on the level of elementary or secondary school. Taking into consideration the weight of the patients, it appeared that most women had excessive body weight. Most frequently, concomitant hypertension was observed. Moreover, the age at menarche was 12 and 13. Demographic factors exert a significant effect on the incidence of endometrial cancer. 1. Overweight and obesity are important risk factors of endometrial cancer. 2. A strong relationship is observed between the occurrence of hypertension or diabetes, and the development of endometrial cancer. 3. Women who come from the rural environment and continue to live in this environment are more likely to contract endometrial cancer.

  18. Trends In News Media Coverage Of Mental Illness In The United States: 1995-2014.

    Science.gov (United States)

    McGinty, Emma E; Kennedy-Hendricks, Alene; Choksy, Seema; Barry, Colleen L

    2016-06-01

    The United States is engaged in ongoing dialogue around mental illness. To assess trends in this national discourse, we studied the volume and content of a random sample of 400 news stories about mental illness from the period 1995-2014. Compared to news stories in the first decade of the study period, those in the second decade were more likely to mention mass shootings by people with mental illnesses. The most frequently mentioned topic across the study period was violence (55 percent overall) divided into categories of interpersonal violence or self-directed (suicide) violence, followed by stories about any type of treatment for mental illness (47 percent). Fewer news stories, only 14 percent, described successful treatment for or recovery from mental illness. The news media's continued emphasis on interpersonal violence is highly disproportionate to actual rates of violence among those with mental illnesses. Research suggests that this focus may exacerbate social stigma and decrease support for public policies that benefit people with mental illnesses. Project HOPE—The People-to-People Health Foundation, Inc.

  19. Comparative Longterm Mortality Trends in Cancer vs. Ischemic Heart Disease in Puerto Rico.

    Science.gov (United States)

    Torres, David; Pericchi, Luis R; Mattei, Hernando; Zevallos, Juan C

    2017-06-01

    Although contemporary mortality data are important for health assessment and planning purposes, their availability lag several years. Statistical projection techniques can be employed to obtain current estimates. This study aimed to assess annual trends of mortality in Puerto Rico due to cancer and Ischemic Heart Disease (IHD), and to predict shorterm and longterm cancer and IHD mortality figures. Age-adjusted mortality per 100,000 population projections with a 50% interval probability were calculated utilizing a Bayesian statistical approach of Age-Period-Cohort dynamic model. Multiple cause-of-death annual files for years 1994-2010 for Puerto Rico were used to calculate shortterm (2011-2012) predictions. Longterm (2013-2022) predictions were based on quinquennial data. We also calculated gender differences in rates (men-women) for each study period. Mortality rates for women were similar for cancer and IHD in the 1994-1998 period, but changed substantially in the projected 2018-2022 period. Cancer mortality rates declined gradually overtime, and the gender difference remained constant throughout the historical and projected trends. A consistent declining trend for IHD historical annual mortality rate was observed for both genders, with a substantial changepoint around 2004-2005 for men. The initial gender difference of 33% (80/100,00 vs. 60/100,000) in mortality rates observed between cancer and IHD in the 1994-1998 period increased to 300% (60/100,000 vs. 20/100,000) for the 2018-2022 period. The APC projection model accurately projects shortterm and longterm mortality trends for cancer and IHD in this population: The steady historical and projected cancer mortality rates contrasts with the substantial decline in IHD mortality rates, especially in men.

  20. Nonmelanoma skin cancer visits and procedure patterns in a nationally representative sample: national ambulatory medical care survey 1995-2007.

    Science.gov (United States)

    Wysong, Ashley; Linos, Eleni; Hernandez-Boussard, Tina; Arron, Sarah T; Gladstone, Hayes; Tang, Jean Y

    2013-04-01

    The rising incidence of nonmelanoma skin cancer (NMSC) is well documented, but data are limited on the number of visits and treatment patterns of NMSC in the outpatient setting. To evaluate practice and treatment patterns of NMSC in the United States over the last decade and to characterize differences according to sex, age, race, insurance type, and physician specialty. Adults with an International Classification of Diseases, Ninth Revision, diagnosis of NMSC were included in this cross-sectional survey study of the National Ambulatory Medical Care Survey between 1995 and 2007. Primary outcomes included population-adjusted NMSC visit rates and odds ratios of receiving a procedure for NMSC using logistic regression. Rates of NMSC visits increased between 1995 and 2007. The number of visits was significantly higher in men, particularly those aged 65 and older. Fifty-nine percent of NMSC visits were associated with a procedure, and the individuals associated with that visit were more likely to be male, to be seen by a dermatologist, and to have private-pay insurance. Nonmelanoma skin cancer visit rates increased from 1995 to 2007 and were higher in men than women. Visits to a dermatologist are more likely to be associated with a procedure for NMSC, and there may be discrepancies in treatment patterns based on insurance type and sex. © 2013 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.

  1. Prostate cancer in East Asia: evolving trend over the last decade

    Directory of Open Access Journals (Sweden)

    Yao Zhu

    2015-02-01

    Full Text Available Prostate cancer is now becoming an emerging health priority in East Asia. Most of our current knowledge on Prostate cancer has been generated from studies conducted in Western population; however, there is considerable heterogeneity of Prostate cancer between East and West. In this article, we reviewed epidemiologic trends, risk factors, disease characteristics and management of Prostate cancer in East Asian population over the last decade. Growing evidence from East Asia suggests an important role of genetic and environmental risk factors interactions in the carcinogenesis of Prostate cancer. Exposure to westernized diet and life style and improvement in health care in combination contribute substantially to the increasing epidemic in this region. Diagnostic and treatment guidelines in East Asia are largely based on Western knowledge. Although there is a remarkable improvement in the outcome over the last decade, ample evidence suggests an inneglectable difference in diagnostic accuracy, treatment efficacy and adverse events between different populations. The knowledge from western countries should be calibrated in the Asian setting to provide a better race-based treatment approach. In this review, we intend to reveal the evolving trend of Prostate cancer in the last decade, in order to gain evidence to improve Prostate cancer prevention and control in East Asia.

  2. Public endorsement of restrictions on three aspects of free expression by homosexuals: socio-demographic and trends analysis 1973-1988.

    Science.gov (United States)

    Dejowski, E F

    1992-01-01

    The willingness of the public to endorse proposals to remove gay-positive books from library shelves, to dismiss college teachers who are homosexuals, and to prohibit public speaking by homosexuals was examined. A socio-demographic analysis aggregating the entire period 1973 through 1988, and an analysis of trends over the period, were undertaken using data from the General Social Surveys. Responses to survey questions concerning homosexuals were compared with responses to similar questions concerning other unpopular groups, and to questions which called upon the respondent to make a moral judgment concerning homosexual relations. A significant decline over the period was found in the public's willingness to endorse restrictions on homosexuals, and on each of the other unpopular groups used for comparison. Level of education appeared to be a strong indicator of a more tolerant attitude. Paradoxically, negative moral attitudes toward homosexual relations did not decline. Bias in the wording of the General Social Surveys' questions concerning the moral dimension of homosexuality may have distorted these results, however. The public's moral attitude toward homosexual behavior does appear to be quite labile from year to year, suggesting that concerted efforts to educate the public on this subject can have an important and rapid effect.

  3. The trends in total energy, macronutrients and sodium intake among Japanese: findings from the 1995-2016 National Health and Nutrition Survey.

    Science.gov (United States)

    Saito, Aki; Imai, Shino; Htun, Nay Chi; Okada, Emiko; Yoshita, Katsushi; Yoshiike, Nobuo; Takimoto, Hidemi

    2018-06-04

    Monitoring nutritional status of the population is essential in the development and evaluation of national or local health policies. In this study, we aimed to demonstrate analysis on the trends in dietary intake of energy and macronutrients, as well as Na, in Japanese population using the data of series of cross-sectional national surveys - the National Nutrition Survey (NNS) and the National Health Nutrition Survey (NHNS) - during the period from 1995 to 2016. The NNS and NHNS participants aged 20-79 years were included in the analysis. Dietary intake was estimated using 1-d household-based dietary record. The trend in total energy intake, energy intake from macronutrients (fat and protein), Na intake and energy-adjusted Na intake were analysed using regression models adjusted to 2010 age distribution and anthropometry status. A total of 94 270 men and 107 890 women were included the analysis. Total energy intake showed a decreasing trend in both men and women. Similarly, energy intake from protein decreased, but energy intake (%) from fat increased in both sexes. Energy-adjusted Na intake showed a decreasing trend in both men and women. This study identified the decrease in total energy intake and energy intake from protein, whereas there were inverse trends in energy intake from fat among Japanese adults. Continued monitoring of trends in dietary intake will be needed, and there should be efforts to increase the accuracy of current survey procedures.

  4. Recent adverse trends in semen quality and testis cancer incidence among Finnish men

    DEFF Research Database (Denmark)

    Jorgensen, N.; Vierula, M.; Jacobsen, R.

    2011-01-01

    Impaired semen quality and testicular cancer may be linked through a testicular dysgenesis syndrome of foetal origin. The incidence of testis cancer has been shown to increase among Finnish men, whereas there is no recent publication describing temporal trends in semen quality. Therefore, we...... carried out a prospective semen quality study and a registry study of testis cancer incidence among Finnish men to explore recent trends. A total of 858 men were investigated in the semen quality study during 1998-2006. Median sperm concentrations were 67 (95% CI 57-80) million/mL, 60 (51-71) and 48 (39...

  5. Development of the techniques of radiotherapy of lung cancer in the republic of belarus (1970-1995)

    International Nuclear Information System (INIS)

    Muravskaya, G.V.; Artemova, N.A.; Golub, G.D.; Krutilina, N.I.; Minajlo, I.I.; Sinajko, V.V.; Suravikina, V.V.; Ulitskij, P.I.

    1996-01-01

    A 25-year (1970-1995) experience in clinical employment of original and improved techniques of radiation treatment in the management of more than 12,000 lung cancer patients is assessed. The employment of the new methods of radiotherapy of operable stage III squamous-cell lung cancer patients increased their 5-year survival rate from 8±3% to 42±5%, and that of inoperable stage II-III patients - from 5 to 9%. An original method of chemoradiotherapy of stage II-III small-cell cancer enabled to raise 5-year survival rate from 4 to 12%. Owing to the reduction in the number of patients declining special treatment (from 32 to 13.7%) and widening the range of indications to treatment (from 65 to 83%) the rate of clinical group II lung cancer patients administered special treatment rose more than twice (from 32.4 to 69.3%) over the past 15 years. The proportion of lung cancer patients among all cancer patients being on the register for more than 5 years in the Republic of Belarus increased more than 3-fold (from 8 to 26.7%) over the past 20 years

  6. Geriatric cancer trends in the Middle-East: Findings from Lebanese cancer projections until 2025.

    Science.gov (United States)

    Haddad, Fady Gh; Kattan, Joseph; Kourie, Hampig R; El Rassy, Elie; Assi, Tarek; Adib, Salim M

    2018-03-01

    By 2020, 70% of all cancers will occur in patients aged 65years and older, causing an increase in related morbidity, mortality, and cost. This study projects cancer trends in the elderly population in Lebanon, a country experiencing accelerating aging trends. Findings will guide future policy decisions regarding geriatric oncology in Lebanon and the surrounding Arab world. Cancer incidence rates were derived for men and women 65years and above, divided into three age groups: 65-69years, 70-74years, and 75years and above. Raw data were obtained from the National Cancer Registry reports 2003-2010. The eight consecutive year data were used to project the incidence until 2025 using a logarithmic model. The Average Annual Percent Change in incidence rates was calculated to determine whether it would significantly increase, decrease, or remain stable over time. Incidence rates are projected to increase significantly in all age groups of both genders until 2025. In men, the fastest rise is expected in prostate cancer, followed by bladder, lung, colorectal, and NHL. In women, the rise will be fastest in breast, followed by colorectal, lung, NHL, and ovary. Projected rates increase faster in the "younger" age group 65-69 compared to the "oldest" ≥75, both in men and women. Only kidney and liver cancers continue to rise significantly after 75. Cancer incidence is projected to increase in individuals between 65 and 74years of age. Lebanese and Middle Eastern physicians must implement adapted therapeutic strategies in the management of the increasing caseload among frail, elderly patients. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. MORTALITY TRENDS FOR MOST COMMON TYPES OF CANCER IN SILESIA VOIVODESHIP IN SHORT TERM PROJECTION

    Directory of Open Access Journals (Sweden)

    Brunon Zemła

    2011-06-01

    Full Text Available Background: The incidence of morbidity and mortality of cancers rapidly increase in the world and so it is in case of Poland and Silesia Voivodeship. Therefore an attempt is made to assess this phenomenon in projection scale within Silesia Voivodeship. Materials and methods: The time-trends analysis of the six most common types of cancer have been selected: stomach, colorectal, pancreas and lung (among both genders, prostate (among males and breast (among females. For the period 1990–2008 age standardized mortality rates have been determined. Time-trends in mortality with employment of joinpoint regression have been estimated and depending on trends linear or log-linear regression models were used which set up the base for short-term projection. Results: For the year 2018 projection values of mortality rates among males will drop (with the exception of lung and colorectal cancers. For prostate cancer – the values will be increasing. Among females stomach mortality rates will drop, but again lung cancer mortality rate will double in comparison to data for 1990. Conclusions: 1. The prognostic number of death to 2018 year concern all studied cancer increasing, for exept stomach cancer. 2. Especially will be increasing cancer mortality standardized rates for lung cancer among females and prostate and colorectal cancers among males.

  8. National trends in occupational injuries before and after 1992 and predictors of workers' compensation costs.

    Science.gov (United States)

    Bhushan, Abhinav; Leigh, J Paul

    2011-01-01

    Numbers and costs of occupational injuries and illnesses are significant in terms of morbidity and dollars, yet our understanding of time trends is minimal. We investigated trends and addressed some common hypotheses regarding causes of fluctuations. We pulled data on incidence rates (per 100 full-time employed workers) for injuries and illnesses from the U.S. Bureau of Labor Statistics and on costs and benefits from the National Academy of Social Insurance for 1973 through 2007. Rates reflected all injury and illness cases, lost work-time cases, and cases resulting in at least 31 days away from work. We adjusted dollar costs (premiums) and benefits for inflation and measured them per employed worker. We plotted data in time-trend charts and ran linear regressions. From 1973 to 1991, there was a weak to nonexistent downward trend for injury and illness rates, and rates were strongly and negatively correlated with the unemployment rate. From 1992 to 2007, there were strong, consistent downward trends, but no longer were there statistically significant correlations with unemployment. Significant predictors (and signs) of workers' compensation premiums for 1973-2007 included medical price inflation (positive), number of lost-time injuries (positive), the Dow Jones Industrial Average (negative), and inflation-adjusted interest rate on U.S. Treasury bonds (negative). Dollars of benefits were positively and significantly predicted by medical inflation and number of lost-time cases. For 1992-2007, the Dow Jones variable was the only robust predictor of premiums; the number of injuries was not a significant positive predictor. We had two major conclusions. First, the year 1992 marked a sharp contrast in trends and correlations between unemployment and incidence rates for occupational injuries and illnesses. Second, for the entire time period (1973-2007), insurance carriers' premiums were strongly associated with returns on investments.

  9. Brain cancer incidence trends in relation to cellular telephone use in the United States.

    Science.gov (United States)

    Inskip, Peter D; Hoover, Robert N; Devesa, Susan S

    2010-11-01

    The use of cellular telephones has grown explosively during the past two decades, and there are now more than 279 million wireless subscribers in the United States. If cellular phone use causes brain cancer, as some suggest, the potential public health implications could be considerable. One might expect the effects of such a prevalent exposure to be reflected in general population incidence rates, unless the induction period is very long or confined to very long-term users. To address this issue, we examined temporal trends in brain cancer incidence rates in the United States, using data collected by the Surveillance, Epidemiology, and End Results (SEER) Program. Log-linear models were used to estimate the annual percent change in rates among whites. With the exception of the 20-29-year age group, the trends for 1992-2006 were downward or flat. Among those aged 20-29 years, there was a statistically significant increasing trend between 1992 and 2006 among females but not among males. The recent trend in 20-29-year-old women was driven by a rising incidence of frontal lobe cancers. No increases were apparent for temporal or parietal lobe cancers, or cancers of the cerebellum, which involve the parts of the brain that would be more highly exposed to radiofrequency radiation from cellular phones. Frontal lobe cancer rates also rose among 20-29-year-old males, but the increase began earlier than among females and before cell phone use was highly prevalent. Overall, these incidence data do not provide support to the view that cellular phone use causes brain cancer.

  10. UV Exposure and Sun-Protective Behavior - Prevention Summary Table | Cancer Trends Progress Report

    Science.gov (United States)

    The Cancer Trends Progress Report, first issued in 2001, summarizes our nation's advances against cancer in relation to Healthy People targets set forth by the Department of Health and Human Services.

  11. Colorectal cancer mortality trends in Serbia during 1991-2010: an age-period-cohort analysis and a joinpoint regression analysis.

    Science.gov (United States)

    Ilic, Milena; Ilic, Irena

    2016-06-22

    For both men and women worldwide, colorectal cancer is among the leading causes of cancer-related death. This study aimed to assess the mortality trends of colorectal cancer in Serbia between 1991 and 2010, prior to the introduction of population-based screening. Joinpoint regression analysis was used to estimate average annual percent change (AAPC) with the corresponding 95% confidence interval (CI). Furthermore, age-period-cohort analysis was performed to examine the effects of birth cohort and calendar period on the observed temporal trends. We observed a significantly increased trend in colorectal cancer mortality in Serbia during the study period (AAPC = 1.6%, 95% CI 1.3%-1.8%). Colorectal cancer showed an increased mortality trend in both men (AAPC = 2.0%, 95% CI 1.7%-2.2%) and women (AAPC = 1.0%, 95% CI 0.6%-1.4%). The temporal trend of colorectal cancer mortality was significantly affected by birth cohort (P < 0.05), whereas the study period did not significantly affect the trend (P = 0.072). Colorectal cancer mortality increased for the first several birth cohorts in Serbia (from 1916 to 1955), followed by downward flexion for people born after the 1960s. According to comparability test, overall mortality trends for colon cancer and rectal and anal cancer were not parallel (the final selected model rejected parallelism, P < 0.05). We found that colorectal cancer mortality in Serbia increased considerably over the past two decades. Mortality increased particularly in men, but the trends were different according to age group and subsite. In Serbia, interventions to reduce colorectal cancer burden, especially the implementation of a national screening program, as well as treatment improvements and measures to encourage the adoption of a healthy lifestyle, are needed.

  12. Facilitating working mothers' ability to breastfeed: global trends in guaranteeing breastfeeding breaks at work, 1995-2014.

    Science.gov (United States)

    Atabay, Efe; Moreno, Gonzalo; Nandi, Arijit; Kranz, Gabriella; Vincent, Ilona; Assi, Tina-Marie; Winfrey, Elise Marie Vaughan; Earle, Alison; Raub, Amy; Heymann, S Jody

    2015-02-01

    Mothers who work away from home tend to stop breastfeeding earlier than their nonworking counterparts due to workplace barriers. Barriers to breastfeeding discriminate against women and may lead to inequities in children's health outcomes. Guaranteeing paid breastfeeding breaks at work is 1 mechanism that can improve mothers' opportunity to breastfeed in the workplace. This study aimed to assess the trends in the share of countries guaranteeing breastfeeding breaks in the workplace and paid maternal leave that lasts until the infant is 6 months old (the World Health Organization recommended duration for exclusive breastfeeding), between 1995 and 2014. Legislation and secondary source data were collected and reviewed for 193 United Nations member states. Legislation was analyzed for content on breastfeeding breaks and maternal leave guarantees. Fifty-one countries (26.7%) in 2014 did not guarantee breastfeeding breaks in any form and 4 countries provided only unpaid breaks or breaks that did not cover the first 6 months of life; since 1995, around 15 countries (10.2%) legislated for such a policy. In 2014, out of 55 countries that did not guarantee paid breastfeeding breaks for the first 6 months after birth, 7 countries guaranteed paid maternal leave for the same duration; 48 countries (25.1%) provided neither paid maternal leave nor paid breastfeeding breaks. Progress in the number of countries guaranteeing breastfeeding breaks at work is modest. Adopting measures to facilitate breastfeeding at work can be a critical opportunity for countries to increase breastfeeding rates among the growing number of women in the labor force. © The Author(s) 2014.

  13. Gastric cancer mortality trends in Spain, 1976-2005, differences by autonomous region and sex

    International Nuclear Information System (INIS)

    García-Esquinas, Esther; Pérez-Gómez, Beatriz; Pollán, Marina; Boldo, Elena; Fernández-Navarro, Pablo; Lope, Virginia; Vidal, Enrique; López-Abente, Gonzalo; Aragonés, Nuria

    2009-01-01

    Gastric cancer is the second leading cause of oncologic death worldwide. One of the most noteworthy characteristics of this tumor's epidemiology is the marked decline reported in its incidence and mortality in almost every part of the globe in recent decades. This study sought to describe gastric cancer mortality time trends in Spain's regions for both sexes. Mortality data for the period 1976 through 2005 were obtained from the Spanish National Statistics Institute. Cases were identified using the International Classification of Diseases 9 th and 10 th revision (codes 151 and C16, respectively). Crude and standardized mortality rates were calculated by geographic area, sex, and five-year period. Joinpoint regression analyses were performed to ascertain whether changes in gastric cancer mortality trends had occurred, and to estimate the annual percent change by sex and geographic area. Gastric cancer mortality decreased across the study period, with the downward trend being most pronounced in women and in certain regions situated in the interior and north of mainland Spain. Across the study period, there was an overall decrease of 2.90% per annum among men and 3.65% per annum among women. Generally, regions in which the rate of decline was sharpest were those that had initially registered the highest rates. However, the rate of decline was not constant throughout the study period: joinpoint analysis detected a shift in trend for both sexes in the early 1980s. Gastric cancer mortality displayed in both sexes a downward trend during the study period, both nationally and regionally. The different trend in rates in the respective geographic areas translated as greater regional homogeneity in gastric cancer mortality by the end of the study period. In contrast, rates in women fell more than did those in men. The increasing differences between the sexes could indicate that some risk factors may be modifying the sex-specific pattern of this tumor

  14. Consumer attitudes and misperceptions associated with trends in self-reported cereal foods consumption: cross-sectional study of Western Australian adults, 1995 to 2012.

    Science.gov (United States)

    Pollard, Christina Mary; Pulker, Claire Elizabeth; Meng, Xingqiong; Scott, Jane Anne; Denham, Felicity Claire; Solah, Vicky Anne; Kerr, Deborah Anne

    2017-06-26

    The reasons for low adherence to cereal dietary guidelines are not well understood but may be related to knowledge, attitudes, beliefs and perceived barriers. This study aims to assess trends in cereal foods consumption, intention to change and factors associated with intake among Western Australian (WA) adults 18 to 64 years. Cross-sectional data from the 1995, 1998, 2001, 2004, 2009, and 2012 Nutrition Monitoring Survey Series involving 7044 adults were pooled. types and amount of cereals (bread, rice, pasta, and breakfast cereal) eaten the day prior. Attitudes, knowledge, intentions, weight status and sociodemographic characteristics were measured. Descriptive statistics, multiple binary logistic and multinomial logistic regressions assess factors associated with consumption. Bread (78%) was the most commonly consumed cereal food. The proportion eating bread decreased across survey years (Odds Ratio OR = 0.31; 95% Confidence Interval; 0.24-0.40 in 2012 versus 1995), as did the amount (4.1 slices of bread in 1995 to 2.4 in 2012). The odds of consuming whole-grain cereal foods increased since 2009 (OR = 1.27; 1.02-1.58 versus 1995 p < 0.05). The likelihood of trying to eat less cereal food in the past year was greater in 2012 compared to 1995 (Relative Risk Ratio RRR 10.88; 6.81-17.4). Knowledge of cereal recommendations decreased over time (OR = 0.20; 0.15-0.27 in 2012 versus 1995 p < 0.001). Overweight and obese respondents were more likely than healthy weight respondents to have tried to eat less cereals (RRR 1.65; 1.22-2.24 and 1.88; 1.35-2.63 respectively). 'I already eat enough' was the main barrier (75% in 1995 to 84% in 2012 (p < 0.001)). WA adults are actively reducing the amount of cereal foods they eat and intake is associated with a misperception of adequacy of intake. Nutrition intervention is needed to increase awareness of the health benefits of cereal foods, particularly whole-grains, and to address barriers to incorporating them daily

  15. Consumer attitudes and misperceptions associated with trends in self-reported cereal foods consumption: cross-sectional study of Western Australian adults, 1995 to 2012

    Directory of Open Access Journals (Sweden)

    Christina Mary Pollard

    2017-06-01

    Full Text Available Abstract Background The reasons for low adherence to cereal dietary guidelines are not well understood but may be related to knowledge, attitudes, beliefs and perceived barriers. This study aims to assess trends in cereal foods consumption, intention to change and factors associated with intake among Western Australian (WA adults 18 to 64 years. Method Cross-sectional data from the 1995, 1998, 2001, 2004, 2009, and 2012 Nutrition Monitoring Survey Series involving 7044 adults were pooled. Outcome variables: types and amount of cereals (bread, rice, pasta, and breakfast cereal eaten the day prior. Attitudes, knowledge, intentions, weight status and sociodemographic characteristics were measured. Descriptive statistics, multiple binary logistic and multinomial logistic regressions assess factors associated with consumption. Results Bread (78% was the most commonly consumed cereal food. The proportion eating bread decreased across survey years (Odds Ratio OR = 0.31; 95% Confidence Interval; 0.24–0.40 in 2012 versus 1995, as did the amount (4.1 slices of bread in 1995 to 2.4 in 2012. The odds of consuming whole-grain cereal foods increased since 2009 (OR = 1.27; 1.02–1.58 versus 1995 p < 0.05. The likelihood of trying to eat less cereal food in the past year was greater in 2012 compared to 1995 (Relative Risk Ratio RRR 10.88; 6.81–17.4. Knowledge of cereal recommendations decreased over time (OR = 0.20; 0.15–0.27 in 2012 versus 1995 p < 0.001. Overweight and obese respondents were more likely than healthy weight respondents to have tried to eat less cereals (RRR 1.65; 1.22–2.24 and 1.88; 1.35–2.63 respectively. ‘I already eat enough’ was the main barrier (75% in 1995 to 84% in 2012 (p < 0.001. Conclusions WA adults are actively reducing the amount of cereal foods they eat and intake is associated with a misperception of adequacy of intake. Nutrition intervention is needed to increase awareness of the health benefits of

  16. Radiation Dose and Subsequent Risk for Stomach Cancer in Long-term Survivors of Cervical Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Kleinerman, Ruth A., E-mail: kleinerr@mail.nih.gov [Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Rockville, Maryland (United States); Smith, Susan A. [Department of Radiation Physics, University of Texas M D Anderson Cancer Center, Houston, Texas (United States); Holowaty, Eric [Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario (Canada); Hall, Per [Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm (Sweden); Pukkala, Eero [Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki (Finland); Vaalavirta, Leila [Department of Oncology, Helsinki University Central Hospital, Helsinki (Finland); Stovall, Marilyn; Weathers, Rita [Department of Radiation Physics, University of Texas M D Anderson Cancer Center, Houston, Texas (United States); Gilbert, Ethel [Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Rockville, Maryland (United States); Aleman, Berthe M.P. [Department of Radiotherapy, The Netherlands Cancer Institute, Amsterdam (Netherlands); Kaijser, Magnus [Clinical Epidemiology Unit, Department of Medicine, Karolinska Institute, Stockholm (Sweden); Andersson, Michael [Department of Oncology, Copenhagen University Hospital, Copenhagen (Denmark); Storm, Hans [Cancer Prevention and Documentation, Danish Cancer Society, Copenhagen (Denmark); Joensuu, Heikki [Department of Oncology, Helsinki University Central Hospital, Helsinki (Finland); Lynch, Charles F. [Department of Epidemiology, University of Iowa, Iowa City, Iowa (United States); and others

    2013-08-01

    Purpose: To assess the dose–response relationship for stomach cancer after radiation therapy for cervical cancer. Methods and Materials: We conducted a nested, matched case–control study of 201 cases and 378 controls among 53,547 5-year survivors of cervical cancer diagnosed from 1943 to 1995, from 5 international, population-based cancer registries. We estimated individual radiation doses to the site of the stomach cancer for all cases and to corresponding sites for the matched controls (overall mean stomach tumor dose, 2.56 Gy, range 0.03-46.1 and after parallel opposed pelvic fields, 1.63 Gy, range 0.12-6.3). Results: More than 90% of women received radiation therapy, mostly with external beam therapy in combination with brachytherapy. Stomach cancer risk was nonsignificantly increased (odds ratio 1.27-2.28) for women receiving between 0.5 and 4.9 Gy to the stomach cancer site and significantly increased at doses ≥5 Gy (odds ratio 4.20, 95% confidence interval 1.41-13.4, P{sub trend}=.047) compared with nonirradiated women. A highly significant radiation dose–response relationship was evident when analyses were restricted to the 131 cases (251 controls) whose stomach cancer was located in the middle and lower portions of the stomach (P{sub trend}=.003), whereas there was no indication of increasing risk with increasing dose for 30 cases (57 controls) whose cancer was located in the upper stomach (P{sub trend}=.23). Conclusions: Our findings show for the first time a significant linear dose–response relationship for risk of stomach cancer in long-term survivors of cervical cancer.

  17. Radiation Dose and Subsequent Risk for Stomach Cancer in Long-term Survivors of Cervical Cancer

    International Nuclear Information System (INIS)

    Kleinerman, Ruth A.; Smith, Susan A.; Holowaty, Eric; Hall, Per; Pukkala, Eero; Vaalavirta, Leila; Stovall, Marilyn; Weathers, Rita; Gilbert, Ethel; Aleman, Berthe M.P.; Kaijser, Magnus; Andersson, Michael; Storm, Hans; Joensuu, Heikki; Lynch, Charles F.

    2013-01-01

    Purpose: To assess the dose–response relationship for stomach cancer after radiation therapy for cervical cancer. Methods and Materials: We conducted a nested, matched case–control study of 201 cases and 378 controls among 53,547 5-year survivors of cervical cancer diagnosed from 1943 to 1995, from 5 international, population-based cancer registries. We estimated individual radiation doses to the site of the stomach cancer for all cases and to corresponding sites for the matched controls (overall mean stomach tumor dose, 2.56 Gy, range 0.03-46.1 and after parallel opposed pelvic fields, 1.63 Gy, range 0.12-6.3). Results: More than 90% of women received radiation therapy, mostly with external beam therapy in combination with brachytherapy. Stomach cancer risk was nonsignificantly increased (odds ratio 1.27-2.28) for women receiving between 0.5 and 4.9 Gy to the stomach cancer site and significantly increased at doses ≥5 Gy (odds ratio 4.20, 95% confidence interval 1.41-13.4, P trend =.047) compared with nonirradiated women. A highly significant radiation dose–response relationship was evident when analyses were restricted to the 131 cases (251 controls) whose stomach cancer was located in the middle and lower portions of the stomach (P trend =.003), whereas there was no indication of increasing risk with increasing dose for 30 cases (57 controls) whose cancer was located in the upper stomach (P trend =.23). Conclusions: Our findings show for the first time a significant linear dose–response relationship for risk of stomach cancer in long-term survivors of cervical cancer

  18. Lung cancer mortality in European women: trends and predictions.

    Science.gov (United States)

    Bosetti, Cristina; Malvezzi, Matteo; Rosso, Tiziana; Bertuccio, Paola; Gallus, Silvano; Chatenoud, Liliane; Levi, Fabio; Negri, Eva; La Vecchia, Carlo

    2012-12-01

    Female lung cancer mortality increased by 50% between the mid 1960s and the early 2000s in the European Union (EU). To monitor the current lung cancer epidemic in European women, we analyzed mortality trends in 33 European countries between 1970 and 2009 and estimated rates for the year 2015 using data from the World Health Organization. Female lung cancer mortality has been increasing up to recent calendar years in most European countries, with the exceptions of Belarus, Russia, and Ukraine, with relatively low rates, and the UK, Iceland and Ireland, where high rates were reached in mid/late 1990s to leveled off thereafter. In the EU, female lung cancer mortality rates rose over the last decade from 11.3 to 12.7/100,000 (+2.3% per year) at all ages and from 18.6 to 21.5/100,000 (+3.0% per year) in middle-age. A further increase is predicted, to reach 14/100,000 women in 2015. Lung cancer mortality trends have been more favorable over the last decade in young women (20-44 years), particularly in the UK and other former high-risk countries from northern and central/eastern Europe, but also in France, Italy, and Spain where mortality in young women has been increasing up to the early 2000s. In the EU as a whole, mortality at age 20-44 years decreased from 1.6 to 1.4/100,000 (-2.2% per year). Although the female lung cancer epidemic in Europe is still expanding, the epidemic may be controlled through the implementation of effective anti-tobacco measures, and it will probably never reach the top US rates. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  19. Cloud amount/frequency, TRANSMISSIVITY and other data from METEOR from 1973-01-31 to 1973-09-20 (NODC Accession 7700650)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Water depth and other physical profile data collected from January 31, 1973 to September 20, 1973 as part of (GARP) Global Atmospheric Research Program Atlantic...

  20. Trends in intensity modulated radiation therapy use for locally advanced rectal cancer at National Comprehensive Cancer Network centers

    Directory of Open Access Journals (Sweden)

    Marsha Reyngold, MD, PhD

    2018-01-01

    Conclusions: Although most patients with stage II-III rectal cancer at queried National Cancer Institute–designated cancer centers between 2005 and 2011 received 3-dimensional CRT, significant and increasing numbers received IMRT. IMRT utilization is highly variable among institutions and not uniform among sociodemographic groups but may be more consistently embraced in specific clinical settings. Given this trend, comparative-effectiveness research is needed to evaluate the benefits of IMRT for rectal cancer.

  1. Epidemiology and trend of neurological diseases associated to HIV/AIDS. Experience of Mexican patients 1995-2009.

    Science.gov (United States)

    Ramírez-Crescencio, M A; Velásquez-Pérez, L; Ramírez-Crescencio, María Antonieta; Velásquez-Pérez, Leora

    2013-08-01

    The aim of this study was to identify the main neurological conditions associated with HIV/AIDS in Mexican patients treated at the National Institute of Neurology and Neurosurgery (NINN) in Mexico city, the main referral center for patients with disorders of the central and peripheral nervous system. An observational, transversal and descriptive analysis was performed. We reviewed the databases from the Department of Epidemiology and the medical records of patients with AIDS seen during the period from January 1st, 1995 to December 31, 2009. 320 patients were detected, the main conditions related to HIV/AIDS were brain toxoplasmosis (42%), cerebral criptoccocosis (28%), tuberculous meningitis (8.7%), linfoma no Hodking (3.75%), acute HIV infection (3.4%) and AIDS dementia complex (3%). No specific trend on morbility and mortality were detected during the period of study. In Mexico the most common neurological complications of HIV/AIDS are opportunistic infections. Copyright © 2013 Elsevier B.V. All rights reserved.

  2. Prognostic value of histopathology and trends in cervical cancer: a SEER population study

    International Nuclear Information System (INIS)

    Vinh-Hung, Vincent; Bourgain, Claire; Vlastos, Georges; Cserni, Gábor; De Ridder, Mark; Storme, Guy; Vlastos, Anne-Thérèse

    2007-01-01

    Histopathology is a cornerstone in the diagnosis of cervical cancer but the prognostic value is controversial. Women under active follow-up for histologically confirmed primary invasive cervical cancer were selected from the United States Surveillance, Epidemiology, and End Results (SEER) 9-registries public use data 1973–2002. Only histologies with at least 100 cases were retained. Registry area, age, marital status, race, year of diagnosis, tumor histology, grade, stage, tumor size, number of positive nodes, number of examined nodes, odds of nodal involvement, extent of surgery, and radiotherapy were evaluated in Cox models by stepwise selection using the Akaike Information Criteria. There were 30,989 records evaluable. From 1973 to 2002, number of cases dropped from 1,100 new cases/year to 900/year, but adenocarcinomas and adenosquamous carcinoma increased from 100/year to 235/year. Median age was 48 years. Statistically significant variables for both overall and cause-specific mortality were: age, year of diagnosis, race, stage, histology, grade, hysterectomy, radiotherapy, tumor size and nodal ratio. The histological types were jointly significant, P < 0.001. Cause-specific mortality hazard ratios by histological type relatively to non-microinvasive squamous cell carcinoma were: microinvasive squamous cell carcinoma 0.28 (95% confidence interval: 0.20–0.39), carcinoma not otherwise specified 0.91 (0.79–1.04), non-mucinous adenocarcinoma 1.06 (0.98–1.15), adenosquamous carcinoma 1.35 (1.20–1.51), mucinous adenocarcinoma 1.52 (1.23–1.88), small cell carcinoma 1.94 (1.58–2.39). Small cell carcinoma and adenocarcinomas were associated with poorer survival. The incidental observation of increasing numbers of adenocarcinomas despite a general decline suggests the inefficiency of conventional screening for these tumors. Increased incidence of adenocarcinomas, their adverse prognosis, and the young age at diagnosis indicate the need to identify women who

  3. Trends In News Media Coverage Of Mental Illness In The United States: 1995–2014

    Science.gov (United States)

    McGinty, Emma E.; Kennedy-Hendricks, Alene; Choksy, Seema; Barry, Colleen L.

    2016-01-01

    The United States is engaged in ongoing dialogue around mental illness. To assess trends in this national discourse, we studied the volume and content of a random sample of 400 news stories about mental illness from the period 1995–2014. Compared to news stories in the first decade of the study period, those in the second decade were more likely to mention mass shootings by people with mental illnesses. The most frequently mentioned topic across the study period was violence (55 percent overall) divided into categories of interpersonal violence or self-directed (suicide) violence, followed by stories about any type of treatment for mental illness (47 percent). Fewer news stories, only 14 percent, described successful treatment for or recovery from mental illness. The news media’s continued emphasis on interpersonal violence is highly disproportionate to actual rates of violence among those with mental illnesses. Research suggests that this focus may exacerbate social stigma and decrease support for public policies that benefit people with mental illnesses. PMID:27269031

  4. Trends in botanical dietary supplement use among US adults by cancer status: The National Health and Nutrition Examination Survey, 1999 to 2014.

    Science.gov (United States)

    Li, Chao; Hansen, Richard A; Chou, Chiahung; Calderón, Angela I; Qian, Jingjing

    2018-03-15

    Patients with cancer may use botanical dietary supplements (BDS) in an attempt to manage the side effects of chemotherapy, yet evidence about BDS use among patients with cancer is limited. The authors examined trends in BDS use among US adults according to cancer status and patient characteristics. A serial, cross-sectional study was conducted using data from the National Health and Nutrition Examination Survey from 1999 through 2014 (n = 43,644). Self-reported cancer diagnosis history and any BDS use in the preceding 30 days were determined. The prevalence of BDS use was calculated in each cycle for respondents with and without cancer, both overall and by patient characteristics. Simple linear regression models were applied to test for trends in BDS use at a 2-sided P value < .05. Multiple logistic regression models were performed to identify the patient factors associated with BDS use. The results were weighted to represent national estimates. The prevalence of BDS use was greater among participants who had cancer compared with participants who did not have cancer, but trends remained stable during 1999 through 2014 for both groups. Trends in BDS use declined in patients with cancer who were older (P trend  = .047), had a low annual family income (P trend  = .028), and had a lower education level (P trend  = .004). Among the respondents without cancer, trends in BDS use declined in those who were middle-aged (P trend  = .025), non-Hispanic whites (P trend  = .025), those with a lower education level (P trend  = .011), and those who were not receiving prescription medication (P trend  = .036). Patient age, sex, race/ethnicity, income, education, and health conditions were associated with BDS use. The overall use of BDS remained stable during 1999 through 2014 for US adults with and without cancer, but it varied by individual characteristics. Cancer 2018;124:1207-15. © 2017 American Cancer Society. © 2017 American Cancer

  5. Status and trends of land change in the Midwest–South Central United States—1973 to 2000

    Science.gov (United States)

    Auch, Roger F.; Karstensen, Krista A.; Auch, Roger F.; Karstensen, Krista A.

    2015-12-10

    U.S. Geological Survey (USGS) Professional Paper 1794–C is the third in a four-volume series on the status and trends of the Nation’s land use and land cover, providing an assessment of the rates and causes of land-use and land-cover change in the Midwest–South Central United States between 1973 and 2000. Volumes A, B, and D provide similar analyses for the Western United States, the Great Plains of the United States, and the Eastern United States, respectively. The assessments of land-use and land-cover trends are conducted on an ecoregion-by-ecoregion basis, and each ecoregion assessment is guided by a nationally consistent study design that includes mapping, statistical methods, field studies, and analysis. Individual assessments provide a picture of the characteristics of land change occurring in a given ecoregion; in combination, they provide a framework for understanding the complex national mosaic of change and also the causes and consequences of change. Thus, each volume in this series provides a regional assessment of how (and how fast) land use and land cover are changing, and why. The four volumes together form the first comprehensive picture of land change across the Nation.Geographic understanding of land-use and land-cover change is directly relevant to a wide variety of stakeholders, including land and resource managers, policymakers, and scientists. The chapters in this volume present brief summaries of the patterns and rates of land change observed in each ecoregion in the Midwest–South Central United States, together with field photographs, statistics, and comparisons with other assessments. In addition, a synthesis chapter summarizes the scope of land change observed across the entire Midwest–South Central United States. The studies provide a way of integrating information across the landscape, and they form a critical component in the efforts to understand how land use and land cover affect important issues such as the provision of

  6. Prostate cancer trends in Asia.

    Science.gov (United States)

    Akaza, Hideyuki; Onozawa, Mizuki; Hinotsu, Shiro

    2017-06-01

    Differences in the incidence and mortality rates for prostate cancer between East and West are clearly defined, with higher rates in the West and lower rates in the East. Treatment methods are generally selected in accordance with general practice guidelines, but the current reality in Asia is that there is not sufficient clinical data to set Asia-specific guidelines for treatment. This leads to a situation whereby for the large part guidelines based on scientific evidence accumulated in Western countries are followed, but from time to time cases are encountered when such guidelines may not be considered to be the most appropriate for the case at hand. Although there is a relatively large volume of clinical evidence relating to endocrine therapy in Asia, the treatment choices and effects differ to those in the West. These regional differences are thought to be due to various factors, including not only differences in genetic background, but also distinct differences in the living and healthcare environments. If the differences between East and West in terms of trends in prostate cancer could be examined, with positive aspects being adopted and negative aspects being improved, this could also be expected to be of use in developing a better treatment strategy for prostate cancer. The exchanging of information on a broader, global level will enable improvements in prevention, diagnosis and treatment of prostate cancer. It is in pursuit of this objective that it is important to promote high-quality clinical trials and joint epidemiological studies in Asia and work to accumulate data that are comparable to data available in Western countries.

  7. Ethnic and socioeconomic trends in breast cancer incidence in New Zealand

    Directory of Open Access Journals (Sweden)

    Atkinson June

    2010-12-01

    Full Text Available Abstract Background Breast cancer incidence varies between social groups, but differences have not been thoroughly examined in New Zealand. The objectives of this study are to determine whether trends in breast cancer incidence varied by ethnicity and socioeconomic position between 1981 and 2004 in New Zealand, and to assess possible risk factor explanations. Methods Five cohorts of the entire New Zealand population for 1981-86, 1986-1991, 1991-1996, 1996-2001, and 2001-2004 were created, and probabilistically linked to cancer registry records, allowing direct determination of ethnic and socioeconomic trends in breast cancer incidence. Results Breast cancer rates increased across all ethnic and socioeconomic groups between 1981 and 2004. Māori women consistently had the highest age standardised rates, and the difference between Māori and European/Other women increased from 7% in 1981-6 to 24% in 2001-4. Pacific and Asian women had consistently lower rates of breast cancer than European/Other women over the time period studied (12% and 28% lower respectively when pooled over time, although young Pacific women had slightly higher incidence rates than young European/other women. A gradient between high and low income women was evident, with high income women having breast cancer rates approximately 10% higher and this difference did not change significantly over time. Conclusions Differences in breast cancer incidence between European and Pacific women and between socioeconomic groups are explicable in terms of known risk factors. However no straightforward explanation for the relatively high incidence amongst Māori is apparent. Further research to explore high Māori breast cancer rates may contribute to reducing the burden of breast cancer amongst Māori women, as well as improving our understanding of the aetiology of breast cancer.

  8. Regional changes in charcoal-burning suicide rates in East/Southeast Asia from 1995 to 2011: a time trend analysis.

    Directory of Open Access Journals (Sweden)

    Shu-Sen Chang

    2014-04-01

    Full Text Available Suicides by carbon monoxide poisoning resulting from burning barbecue charcoal reached epidemic levels in Hong Kong and Taiwan within 5 y of the first reported cases in the early 2000s. The objectives of this analysis were to investigate (i time trends and regional patterns of charcoal-burning suicide throughout East/Southeast Asia during the time period 1995-2011 and (ii whether any rises in use of this method were associated with increases in overall suicide rates. Sex- and age-specific trends over time were also examined to identify the demographic groups showing the greatest increases in charcoal-burning suicide rates across different countries.We used data on suicides by gases other than domestic gas for Hong Kong, Japan, the Republic of Korea, Taiwan, and Singapore in the years 1995/1996-2011. Similar data for Malaysia, the Philippines, and Thailand were also extracted but were incomplete. Graphical and joinpoint regression analyses were used to examine time trends in suicide, and negative binomial regression analysis to study sex- and age-specific patterns. In 1995/1996, charcoal-burning suicides accounted for <1% of all suicides in all study countries, except in Japan (5%, but they increased to account for 13%, 24%, 10%, 7%, and 5% of all suicides in Hong Kong, Taiwan, Japan, the Republic of Korea, and Singapore, respectively, in 2011. Rises were first seen in Hong Kong after 1998 (95% CI 1997-1999, followed by Singapore in 1999 (95% CI 1998-2001, Taiwan in 2000 (95% CI 1999-2001, Japan in 2002 (95% CI 1999-2003, and the Republic of Korea in 2007 (95% CI 2006-2008. No marked increases were seen in Malaysia, the Philippines, or Thailand. There was some evidence that charcoal-burning suicides were associated with an increase in overall suicide rates in Hong Kong, Taiwan, and Japan (for females, but not in Japan (for males, the Republic of Korea, and Singapore. Rates of change in charcoal-burning suicide rate did not differ by sex/age group

  9. Regional changes in charcoal-burning suicide rates in East/Southeast Asia from 1995 to 2011: a time trend analysis.

    Science.gov (United States)

    Chang, Shu-Sen; Chen, Ying-Yeh; Yip, Paul S F; Lee, Won Jin; Hagihara, Akihito; Gunnell, David

    2014-04-01

    Suicides by carbon monoxide poisoning resulting from burning barbecue charcoal reached epidemic levels in Hong Kong and Taiwan within 5 y of the first reported cases in the early 2000s. The objectives of this analysis were to investigate (i) time trends and regional patterns of charcoal-burning suicide throughout East/Southeast Asia during the time period 1995-2011 and (ii) whether any rises in use of this method were associated with increases in overall suicide rates. Sex- and age-specific trends over time were also examined to identify the demographic groups showing the greatest increases in charcoal-burning suicide rates across different countries. We used data on suicides by gases other than domestic gas for Hong Kong, Japan, the Republic of Korea, Taiwan, and Singapore in the years 1995/1996-2011. Similar data for Malaysia, the Philippines, and Thailand were also extracted but were incomplete. Graphical and joinpoint regression analyses were used to examine time trends in suicide, and negative binomial regression analysis to study sex- and age-specific patterns. In 1995/1996, charcoal-burning suicides accounted for <1% of all suicides in all study countries, except in Japan (5%), but they increased to account for 13%, 24%, 10%, 7%, and 5% of all suicides in Hong Kong, Taiwan, Japan, the Republic of Korea, and Singapore, respectively, in 2011. Rises were first seen in Hong Kong after 1998 (95% CI 1997-1999), followed by Singapore in 1999 (95% CI 1998-2001), Taiwan in 2000 (95% CI 1999-2001), Japan in 2002 (95% CI 1999-2003), and the Republic of Korea in 2007 (95% CI 2006-2008). No marked increases were seen in Malaysia, the Philippines, or Thailand. There was some evidence that charcoal-burning suicides were associated with an increase in overall suicide rates in Hong Kong, Taiwan, and Japan (for females), but not in Japan (for males), the Republic of Korea, and Singapore. Rates of change in charcoal-burning suicide rate did not differ by sex/age group in

  10. Cancer incidence in eastern Morocco: cancer patterns and incidence trends, 2005-2012.

    Science.gov (United States)

    Elidrissi Errahhali, Manal; Elidrissi Errahhali, Mounia; Ouarzane, Meryem; Boulouiz, Redouane; Bellaoui, Mohammed

    2017-08-29

    Cancer is one of the major health problems worldwide. In this article, we present for the first time the cancer incidence trends, the distribution and the socioeconomic profile of incident cancer cases in Eastern Morocco over a period of eight years. Retrospective descriptive study of patients diagnosed with cancer at the Hassan II Regional Oncology Center (ROC) since it was created in October 2005 until December 2012. During the study period, the ROC was the only hospital specialized in cancer care in Eastern Morocco. A total of 7872 incident cases of cancer were registered in Eastern Morocco. Among these incident cases 5220 cases were women and 2652 were men, with a female to male ratio of 1.97. The mean age at diagnosis was 58 years for males and 52 for females and 94% of the patients aged over 30 years. For both sexes combined and for all cancer sites, breast cancer was the commonest followed by cervix uteri, colon-rectum, lung, nasopharynx, and stomach cancers. The most common cancer in women was breast cancer, followed respectively by cervix uteri cancer, colon-rectum cancer, ovary cancer, and stomach cancer. In men, the lung cancer ranked first, followed respectively by colon-rectum cancer, nasopharynx cancer, prostate cancer, and stomach cancer. For most cancers, crude incidence rates (CR) have increased significantly. The CR for all cancers combined has increased from 56.6 to 80.3 per 100,000 females and from 32.3 to 42.6 per 100,000 males during the study period. Patients profile analysis showed that 79% of cancer patients were from urban areas, 83% were unemployed and 85% had no health insurance. The distribution of cancers in Eastern Morocco is different from those observed in other regions of Morocco. Unlike most countries, women were much more affected with cancer than men in Eastern Morocco. More importantly, the rates of many cancers are rising. Therefore, our data justify the need to develop effective programs for cancer control and prevention in

  11. Time trends of esophageal and gastric cancer mortality in China, 1991?2009: an age-period-cohort analysis

    OpenAIRE

    Li, Mengmeng; Wan, Xia; Wang, Yanhong; Sun, Yuanyuan; Yang, Gonghuan; Wang, Li

    2017-01-01

    Esophageal and gastric cancers share some risk factors. This study aimed to compare the long-term trends in mortality rates of esophageal and gastric cancers in China to provide evidence for cancer prevention and control. Mortality data were derived from 103 continuous points of the Disease Surveillance Points system during 1991?2009, stratified by gender and urban-rural locations. Age-period-cohort models were used to disentangle the time trends of esophageal and gastric cancer mortality. Th...

  12. Worldwide trends in surgical techniques in the treatment of esophageal and gastroesophageal junction cancer

    NARCIS (Netherlands)

    Haverkamp, L.; Seesing, M. F J; Ruurda, J. P.; Boone, J.; van Hillegersberg, R.

    The aim of this study was to evaluate the worldwide trends in surgical techniques for esophageal cancer surgery by comparing it to our survey from 2007. In addition, new questions were added for gastroesophageal junction (GEJ) cancer. An international survey on surgery of esophageal and GEJ cancer

  13. Trends of radiation dose to the Slovak population from diagnostic nuclear medicine examinations during the period from 1985 to 1995

    International Nuclear Information System (INIS)

    Ftacnikova, S.; Ragan, P.

    1998-01-01

    A mathematical formalism was used to evaluate the radiation dose to population from radiodiagnostic procedures. Data for the calculation were obtained from questionnaires sent to the 12 Slovak hospitals which involve nuclear medicine departments. The mean effective dose for a procedure was determined by multiplying the administered radioactivity by the effective dose per unit of applied radiopharmaceutical activity; the latter value was taken from the literature. The values of the collective effective dose, total number of examinations, mean effective dose per examination and per capita and the number of examinations in 1000 inhabitants are tabulated for the 1985-1995 period. A favorable decreasing trend in the mean effective dose per examination after 1991 was observed. This was mainly due to the replacement of 131 I labelled compounds by 99m Tc radiopharmaceuticals. An overview of nuclear medicine diagnostic practice for pediatric and adult patients is also presented. The number of diagnostic procedures per 1000 inhabitants is significantly lower than in the most developed countries, and this unfavorable trend is continuing so far. (P.A.)

  14. Time trends in avoidable cancer mortality in Switzerland and neighbouring European countries 1996-2010.

    Science.gov (United States)

    Feller, Anita; Mark, Michael Thomas; Steiner, Annik; Clough-Gorr, Kerri M

    2015-01-01

    What are the trends in avoidable cancer mortality in Switzerland and neighbouring countries? Mortality data and population estimates 1996-2010 were obtained from the Swiss Federal Statistical Office for Switzerland and the World Health Organization Mortality Database (http://www.who.int/healthinfo/mortality_data/en/) for Austria, Germany, France and Italy. Age standardised mortality rates (ASMRs, European standard) per 100 000 person-years were calculated for the population Switzerland and neighbouring countries cancer mortality in persons Switzerland from 16.2 to 20.3 per 100 000 person years, EAPC 2.0 [95% CI 1.4 to 2.6]). Compared with its neighbouring countries, Switzerland showed the lowest rates for all groups of avoidable cancer mortality in males 2008-2010. Overall avoidable cancer mortality decreased, indicating achievements in cancer care and related health policies. However, increasing trends in avoidable cancer mortality through primary prevention for females suggest there is a need in Switzerland and its European neighbouring countries to improve primary prevention.

  15. Renovación historiográfica en el Uruguay de la dictadura y de la reinstitucionalización democrática (1973-1995

    Directory of Open Access Journals (Sweden)

    Zubillaga, Carlos

    1997-08-01

    Full Text Available The author provides an overview of the historical research done in Uruguay in the period from the eve of the military coup of June, 1973 to the present a period of the systematic renewal in this area of scholarship. Over these 25 years there have been significant changes in theoretical criteria, research interests, patterns of cooperation among historians, diffusions of their work, and professionalism in the field.

    Se ofrece un panorama de la situación historiográfica en Uruguay desde los prolegómenos del golpe de Estado (junio de 1973 hasta la actualidad, advirtiendo la renovación sistemática operada en este campo del conocimiento. La indagatoria supone develar los cambios registrados en los criterios teóricos, los intereses temáticos, las modalidades de articulación del colectivo de historiadores, la difusibilidad de la producción historiográfica y la profesionalización de la disciplina.

  16. Trends in gynecologic cancer among elderly women in Denmark, 1980-2012

    DEFF Research Database (Denmark)

    Ør Knudsen, Anja; Schledermann, Doris; Nyvang, Gitte-Bettina

    2016-01-01

    (cancer of the cervix uteri), C54 (corpus uteri cancer), C56 (ovarian cancer) and C57 (Fallopian tube cancer). Data derived from the NORDCAN database with comparable data on cancer incidence, mortality, prevalence and relative survival in the Nordic countries, where the Danish data are delivered from......Background The aim of this analysis was to describe trends in incidence, mortality, prevalence, and survival in Danish women with gynecologic cancer from 1980-2012 comparing women aged 70 years or more with younger women. Material and methods Gynecologic cancers included were ICD-10 codes C53...... the Danish Cancer Registry and the Danish Cause of Death Registry with follow-up for death or emigration until the end of 2013. Results For cervical cancer the incidence decreased among women aged less than 70 years and remained stable among the elderly. The mortality rates were clearly separated by age...

  17. Statistical Survey of Deaths from Non melanoma Skin Cancer in Japan during 54 Years

    International Nuclear Information System (INIS)

    Ohtsuka, H.

    2011-01-01

    The author analyzed the annual trends in the number of deaths from non melanoma skin cancer (NMSC) from 1955 to 2008 in Japan on the basis of the data from the Vital Statistics of Japan. The general trends in the number of deaths from NMSC were downward between 1979 to 1994, but upward after 1995. The general trends in age-standardized death rates were roughly downward, although the death rates plateaued after 1995. The recent annual increased ratio of deaths from NMSC was 3.8% (95% confidence interval: 2.7∼4.9%). The number and proportion of deaths from NMSC among the elderly were increasing in Japan. For females, more than 50% of the deaths occurred recently at or after 85 years of age, whereas, for males, this proportion was at or after 75 years of age, nearly reaching at or after 80 years of age.

  18. Trends in gastric cancer mortality and in the prevalence of Helicobacter pylori infection in Portugal.

    Science.gov (United States)

    Morais, Samantha; Ferro, Ana; Bastos, Ana; Castro, Clara; Lunet, Nuno; Peleteiro, Bárbara

    2016-07-01

    Portugal has the highest gastric cancer mortality rates in Western Europe, along with high prevalences of Helicobacter pylori infection. Monitoring their trends is essential to predict the burden of this cancer. We aimed to quantify time trends in gastric cancer mortality in Portugal and in each administrative region, and to compute short-term predictions, as well as to describe the prevalence of H. pylori infection, through a systematic review. Joinpoint analyses were used to identify significant changes in sex-specific trends in gastric cancer age-standardized mortality rates (ASMR) and to estimate annual percent changes (APC). The most recent trends were considered to compute estimates up to 2020 by adjusting Poisson regression models. We searched PubMed and IndexRMP to identify studies carried out in Portugal reporting the prevalence of H. pylori. Gastric cancer mortality has been decreasing in Portugal since 1971 in men (from ASMR=55.3/100 000; APC=-2.4, 95% confidence interval: -2.5 to -2.3) and since 1970 in women (from ASMR=28.0/100 000; APC=-2.8, 95% confidence interval: -2.9 to -2.7), although large regional differences were observed. Predicted ASMR for 2015 and 2020 were 18.8/100 000 and 16.7/100 000 for men and 8.5/100 000 and 7.4/100 000 for women, respectively. The prevalence of H. pylori varied from almost 5% at 0.5-2 years to just over 90% at 70 years or more. No consistent variation was observed since the 1990s. The downward trends in mortality rates are expected to remain in the next decades. The high prevalence of H. pylori infection across age groups and studies from different periods shows a large potential for decrease in the burden of gastric cancer in Portugal.

  19. Food habits and radionuclide tissue concentrations of Nevada desert bighorn sheep, 1972--1973

    International Nuclear Information System (INIS)

    Brown, K.W.; Smith, D.D.; Bernhardt, D.E.; Giles, K.R.; Helvie, J.B.

    1976-06-01

    The botanical composition of the diet and radionuclide content of selected tissues of desert bighorn sheep (Ovis canadensis nelsoni) collected during the 1972 and 1973 hunting seasons were determined by analyzing rumen contents, and lung, liver, kidney, and bone tissues. Botanical examination of the rumen contents showed that grass exceeded 50 percent of the diet of 10 to 14 animals collected in 1972 and 12 of 18 animals collected in 1973. Desert needlegrass (Stipa speciosa), Indian rice grass (Oryzopsis hymenoides), and squirrel tail (Sitanion hystrix) were the major grasses utilized. The dominant shrub species consumed included the joint firs (Ephedra viridis) and (Ephedra nevadensis), Mohave yucca (Yucca schidigera), and cliff rose (Cowania mexicana). With the exception of potassium-40, gamma-emitting radionuclides were not detected in desert bighorn sheep tissue. The tritium levels reported were within environmental levels. Strontium-90 levels averaged 4.9 and 4.1 pCi/gram of bone ash for 1972 and 1973, respectively, continuing the downward trend observed in recent years. Uranium levels were similar to those reported from cattle grazing the same general geographic areas. The daily consumption for one year of 500 grams of liver containing the highest levels of plutonium and uranium would result in a dose to the human bone, the tissue expected to receive the highest dose, of approximately 1 mrem/year. This is less than 1% of the radiation protection guides for the general population

  20. Secular trends for age at spermarche among Chinese boys from 11 ethnic minorities, 1995–2010: a multiple cross-sectional study

    Science.gov (United States)

    Song, Yi; Ma, Jun; Li, Liu-Bai; Dong, Bin; Wang, Zhiqiang; Agardh, Anette

    2016-01-01

    Objectives We compared the differences in median age at spermarche among 11 ethnic minorities in 2010, estimated the trends regarding age at spermarche in different ethnic minorities from 1995 to 2010, and explored the association of spermarche with body mass index (BMI). Methods We used four cross-sectional Chinese National Surveys on Students’ Constitution and Health (CNSSCH, 1995, 2000, 2005 and 2010), and the total sample size was 40 113 children aged 11–18 years. The median age at spermarche of each ethnic minority was determined by using probit analysis. Logistic regression was used to assess the association of spermarche with BMI. Results In 2010, the ethnic minorities with earliest age at spermarche were Qiang (12.03 years), Zhuang (12.91 years) and Kirghiz (13.17 years); the three ethnic minorities with latest age at spermarche were Dong (14.73 years), Yao (14.60 years), and Naxi (14.36 years). From 1995 to 2010, age at spermarche showed a decline in almost each minority group except Yao and Dong. A higher BMI was associated with an increased likelihood of having reached spermarche after adjusting for age, regions or ethnic minorities. Conclusions A large variation in age at spermarche was observed among different ethnic minorities. The age at spermarche showed a downward shift in almost each of the 11 ethnic minorities with different patterns over time, and the children with higher BMI are more likely to enter puberty early. PMID:26911588

  1. Time trend and age-period-cohort effect on kidney cancer mortality in Europe, 1981–2000

    Directory of Open Access Journals (Sweden)

    López-Abente Gonzalo

    2006-05-01

    Full Text Available Abstract Background The incorporation of diagnostic and therapeutic improvements, as well as the different smoking patterns, may have had an influence on the observed variability in renal cancer mortality across Europe. This study examined time trends in kidney cancer mortality in fourteen European countries during the last two decades of the 20th century. Methods Kidney cancer deaths and population estimates for each country during the period 1981–2000 were drawn from the World Health Organization Mortality Database. Age- and period-adjusted mortality rates, as well as annual percentage changes in age-adjusted mortality rates, were calculated for each country and geographical region. Log-linear Poisson models were also fitted to study the effect of age, death period, and birth cohort on kidney cancer mortality rates within each country. Results For men, the overall standardized kidney cancer mortality rates in the eastern, western, and northern European countries were 20, 25, and 53% higher than those for the southern European countries, respectively. However, age-adjusted mortality rates showed a significant annual decrease of -0.7% in the north of Europe, a moderate rise of 0.7% in the west, and substantial increases of 1.4% in the south and 2.0% in the east. This trend was similar among women, but with lower mortality rates. Age-period-cohort models showed three different birth-cohort patterns for both men and women: a decrease in mortality trend for those generations born after 1920 in the Nordic countries, a similar but lagged decline for cohorts born after 1930 in western and southern European countries, and a continuous increase throughout all birth cohorts in eastern Europe. Similar but more heterogeneous regional patterns were observed for period effects. Conclusion Kidney cancer mortality trends in Europe showed a clear north-south pattern, with high rates on a downward trend in the north, intermediate rates on a more marked rising

  2. Cancer incidence among residents of the Three Mile Island accident area: 1982-1995.

    Science.gov (United States)

    Han, Yueh-Ying; Youk, Ada O; Sasser, Howell; Talbott, Evelyn O

    2011-11-01

    The Pennsylvania Department of Health established a registry of the Three Mile Island (TMI) nuclear power plant accident in 1979. Over 93% of the population present on the day of the accident within a 5-mile radius was enrolled and interviewed. We used the registry to investigate the potential cancer risk from low-dose radiation exposure among the TMI population. Cancer incidence data among the TMI cohort were available from 1982 to 1995. Because more than 97% of the population were white and few cancer cases were reported for those younger than 18 years of age, we included whites of age 18 years and older (10,446 men and 11,048 women) for further analyses. Cox regression models were used to estimate the relative risk (RR) per 0.1 mSv and 95% confident interval (CI) of cancer by radiation-related exposures. The cancers of interest were all malignant neoplasms, cancer of bronchus, trachea, and lung, cancer of lymphatic and hematopoietic tissues, leukemia, and female breast. Among men and women, there was no evidence of an increased risk for all malignant neoplasms among the TMI cohort exposed to higher maximum and likely γ radiation (RR=1.00, 95% CI=0.97, 1.01 and RR=0.99, 95% CI=0.94, 1.03, respectively) after adjusting for age, gender, education, smoking, and background radiation. Elevation in risk was noted for cancer of the bronchus, trachea, and lung in relation to higher background radiation exposure (RR=1.45, 95% CI=1.02-2.05 at 8.0-8.8 μR/h compared to 5.2-7.2 μR/h). An increased risk of leukemia was found among men exposed to higher maximum and likely γ radiation related to TMI exposure during the ten days following the accident (RR=1.15, 95% CI=1.04, 1.29 and RR=1.36, 95% CI=1.08, 1.71, respectively). This relationship was not found in women. Increased cancer risks from low-level radiation exposure within the TMI cohort were small and mostly statistically non-significant. However, additional follow-up on this population is warranted, especially to

  3. CSIR Annual report 1973

    CSIR Research Space (South Africa)

    CSIR

    1973-01-01

    Full Text Available This report provides highlights on the activities and achievements of CSIR in the year 1973. An outline of the CSIR structure and financial statements are also presented in the report....

  4. Divergent estrogen receptor-positive and -negative breast cancer trends and etiologic heterogeneity in Denmark

    DEFF Research Database (Denmark)

    Anderson, William F; Rosenberg, Philip S; Petito, Lucia

    2013-01-01

    -period-cohort models to estimate age-specific EAPCs, cohort rate ratios and projections for future time periods (2011-2018). In Denmark, the overall rate of ER-positive cancers rose between 1993 and 2010 by 3.0% per year (95% CI: 2.8-3.3% per year), whereas the overall rate of ER-negative cancers fell by 2.1% per year...... (95% CI: -2.5 to -1.6% per year). The ER-positive rate increased fastest among postmenopausal women and the ER-negative rate decreased fastest among premenopausal women, reflecting that cohorts born after 1944 were at relatively higher risk of ER-positive tumors and lower risk of ER-negative tumors......Long-term breast cancer trends in incidence in the United States (US) show rising estrogen receptor (ER)-positive rates and falling ER-negative rates. We hypothesized that these divergent trends reflect etiologic heterogeneity and that comparable trends should be observed in other countries...

  5. Cancer Among Children With Perinatal Exposure to HIV and Antiretroviral Medications--New Jersey, 1995-2010.

    Science.gov (United States)

    Ivy, Wade; Nesheim, Steve R; Paul, Sindy M; Ibrahim, Abdel R; Chan, Miranda; Niu, Xiaoling; Lampe, Margaret A

    2015-09-01

    Concerns remain regarding the cancer risk associated with perinatal antiretroviral (ARV) exposure among infants. No excessive cancer risk has been found in short-term studies. Children born to HIV-infected women (HIV-exposed) in New Jersey from 1995 to 2008 were identified through the Enhanced HIV/AIDS Reporting System and cross-referenced with data from the New Jersey State Cancer Registry to identify new cases of cancer among children who were perinatally exposed to ARV. Matching of individuals in the Enhanced HIV/AIDS Reporting System to the New Jersey State Cancer Registry was conducted based on name, birth date, Social Security number, residential address, and sex using AutoMatch. Age- and sex-standardized incidence ratio (SIR) and exact 95% confidence intervals (CIs) were calculated using New Jersey (1979-2005) and US (1999-2009) cancer rates. Among 3087 children (29,099 person-years; median follow-up: 9.8 years), 4 were diagnosed with cancer. Cancer incidence among HIV-exposed children who were not exposed to ARV prophylaxis (22.5 per 100,000 person-years) did not differ significantly from the incidence among children who were exposed to any perinatal ARV prophylaxis (14.3 per 100,000 person-years). Furthermore, the number of cases observed among individuals exposed to ARV did not differ significantly from cases expected based on state (SIR = 1.21; 95% CI: 0.25 to 3.54) and national (SIR = 1.27; 95% CI: 0.26 to 3.70) reference rates. Our findings are reassuring that current use of ARV for perinatal HIV prophylaxis does not increase cancer risk. We found no evidence to alter the current federal guidelines of 2014 that recommend ARV prophylaxis of HIV-exposed infants.

  6. The price of crude oil between 1973 et 2014: a cyclical trend over the long term

    International Nuclear Information System (INIS)

    Bui Xuan Hoi

    2015-01-01

    In 2014, given the geopolitical events occurring in regions that are highly sensitive for oil markets - Iraq, Iran, Syria, Russia, the Ukraine, etc. -, one could have expected a hike in the price of a barrel of crude oil. In fact, the opposite happened. Does this mean the end of a cycle characterised by high prices and the beginning of a new cycle epitomised by low prices on the international market place? What is really the mechanism behind long term price formation? Some of the answers emanate from the analysis of the 1973-2014 period. (author)

  7. Trends in adult cardiovascular disease risk factors and their socio-economic patterning in the Scottish population 1995–2008: cross-sectional surveys

    Science.gov (United States)

    Davies, Carolyn; Gray, Linsay; Bromley, Catherine; Capewell, Simon; Leyland, Alastair H

    2011-01-01

    Objectives To examine secular and socio-economic changes in cardiovascular disease risk factor prevalences in the Scottish population. This could contribute to a better understanding of why the decline in coronary heart disease mortality in Scotland has recently stalled along with a widening of socio-economic inequalities. Design Four Scottish Health Surveys 1995, 1998, 2003 and 2008 (6190, 6656, 5497 and 4202 respondents, respectively, aged 25–64 years) were used to examine gender-stratified, age-standardised prevalences of smoking, alcohol consumption, physical activity, fruit and vegetable consumption, discretionary salt use and self-reported diabetes or hypertension. Prevalences were determined according to education and social class. Inequalities were assessed using the slope index of inequality, and time trends were determined using linear regression. Results There were moderate secular declines in the prevalence of smoking, excess alcohol consumption and physical inactivity. Smoking prevalence declined between 1995 and 2008 from 33.4% (95% CI 31.8% to 35.0%) to 29.9% (27.9% to 31.8%) for men and from 36.1% (34.5% to 37.8%) to 27.4% (25.5% to 29.3%) for women. Adverse trends in prevalence were noted for self-reported diabetes and hypertension. Over the four surveys, the diabetes prevalence increased from 1.9% (1.4% to 2.4%) to 3.6% (2.8% to 4.4%) for men and from 1.7% (1.2% to 2.1%) to 3.0% (2.3% to 3.7%) for women. Socio-economic inequalities were evident for almost all risk factors, irrespective of the measure used. These social gradients appeared to be maintained over the four surveys. An exception was self-reported diabetes where, although inequalities were small, the gradient increased over time. Alcohol consumption was unique in consistently showing an inverse gradient, especially for women. Conclusions There has been only a moderate decline in behavioural cardiovascular risk factor prevalences since 1995, with increases in self-reported diabetes

  8. Remarks on Neoechinorhynchus Curemai Noronha, 1973 (Eoacanthocephala, Neoechinorhynchidae

    Directory of Open Access Journals (Sweden)

    Dely Noronha

    1984-06-01

    Full Text Available Data on the host and dimentions of hooks and eggs of N. curemai Noronha, 1973, are retified.Dados sobre o hospedeiro de N. curemai Noronha, 1973, bem como medidas referentes ás dimensões de ganchos e ovos, são retificados.

  9. Sex differences in lung cancer survival: long-term trends using population-based cancer registry data in Osaka, Japan.

    Science.gov (United States)

    Kinoshita, Fukuaki Lee; Ito, Yuri; Morishima, Toshitaka; Miyashiro, Isao; Nakayama, Tomio

    2017-09-01

    Several studies of sex differences in lung cancer survival have been reported. However, large-size population-based studies based on long-term observation are scarce. We investigated long-term trends in sex differences in lung cancer survival using population-based cancer registry data from Osaka, Japan. We analyzed 79 330 cases from the Osaka Cancer Registry (OCR) diagnosed between 1975 and 2007. We calculated 5-year relative survival in the six periods (1975-1980, 1981-1986, 1987-1992, 1993-1997, 1998-2002 and 2003-2007). To estimate the trends in sex differences in lung cancer survival throughout the study period, we applied a multivariate excess hazard model to control for confounders. The proportion of adenocarcinoma (ADC) and 5-year relative relative survival have increased for both sexes. Sex differences in lung cancer survival have widened over the period, especially in ADC and since the late 1990s. The excess hazard ratio of death within 5 years for males was 1.19 (95% CI: 1.16-1.21), adjusting for period at diagnosis, histologic type, stage, age group and treatment. We reported that females have better prognosis in lung cancer than males and the sex differences in lung cancer survival have become wider in Osaka, Japan. This can be partly explained by the sex differences in the proportions of histologic type and stage. Further studies considering other factors that influence sex differences in lung cancer survival are needed. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  10. Trends of energy efficiency in Finnish road freight transport 1995-2009 and forecast to 2016

    Energy Technology Data Exchange (ETDEWEB)

    Liimatainen, Heikki; Poellaenen, Markus [Department of Business Information Management and Logistics, Tampere University of Technology, P.O. Box 541, 33101 Tampere (Finland)

    2010-12-15

    A framework for modeling and analyzing the energy efficiency of road freight transport is presented in this paper. This framework is tested by using the data from the Finnish Goods Transport by Road statistics. The data was enhanced by calculating the fuel consumption for each trip in the data. To calculate this, weight-fuel consumption functions were estimated for each Euro-class vehicles and road type. This is a new method for analyzing the energy efficiency of road freight transport and it could be applied also in other countries gathering freight transport data with continuous company surveys. The analysis show that the energy efficiency of road freight transport in Finland improved during 1995-2002, but has declined since. The major drivers in the development have been the changes in the level of empty running and vehicle fuel efficiency. Extrapolating current statistical trends of factors that influence the energy efficiency show that the target set by the Finnish government for improving energy efficiency by 9% until 2016 will not be achieved. However, the target is possible to be achieved by a combination of small changes to some determinants. (author)

  11. Temporal trends in sperm count

    DEFF Research Database (Denmark)

    Levine, Hagai; Jørgensen, Niels; Martino-Andrade, Anderson

    2017-01-01

    a predefined protocol 7518 abstracts were screened and 2510 full articles reporting primary data on SC were reviewed. A total of 244 estimates of SC and TSC from 185 studies of 42 935 men who provided semen samples in 1973-2011 were extracted for meta-regression analysis, as well as information on years.......006, respectively). WIDER IMPLICATIONS: This comprehensive meta-regression analysis reports a significant decline in sperm counts (as measured by SC and TSC) between 1973 and 2011, driven by a 50-60% decline among men unselected by fertility from North America, Europe, Australia and New Zealand. Because......BACKGROUND: Reported declines in sperm counts remain controversial today and recent trends are unknown. A definitive meta-analysis is critical given the predictive value of sperm count for fertility, morbidity and mortality. OBJECTIVE AND RATIONALE: To provide a systematic review and meta-regression...

  12. Impact of national cancer policies on cancer survival trends and socioeconomic inequalities in England, 1996-2013: population based study

    Science.gov (United States)

    Rachet, Bernard; Belot, Aurélien; Maringe, Camille; Coleman, Michel P

    2018-01-01

    Abstract Objective To assess the effectiveness of the NHS Cancer Plan (2000) and subsequent national cancer policy initiatives in improving cancer survival and reducing socioeconomic inequalities in survival in England. Design Population based cohort study. Setting England. Population More than 3.5 million registered patients aged 15-99 with a diagnosis of one of the 24 most common primary, malignant, invasive neoplasms between 1996 and 2013. Main outcome measures Age standardised net survival estimates by cancer, sex, year, and deprivation group. These estimates were modelled using regression model with splines to explore changes in the cancer survival trends and in the socioeconomic inequalities in survival. Results One year net survival improved steadily from 1996 for 26 of 41 sex-cancer combinations studied, and only from 2001 or 2006 for four cancers. Trends in survival accelerated after 2006 for five cancers. The deprivation gap observed for all 41 sex-cancer combinations among patients with a diagnosis in 1996 persisted until 2013. However, the gap slightly decreased for six cancers among men for which one year survival was more than 65% in 1996, and for cervical and uterine cancers, for which survival was more than 75% in 1996. The deprivation gap widened notably for brain tumours in men and for lung cancer in women. Conclusions Little evidence was found of a direct impact of national cancer strategies on one year survival, and no evidence for a reduction in socioeconomic inequalities in cancer survival. These findings emphasise that socioeconomic inequalities in survival remain a major public health problem for a healthcare system founded on equity. PMID:29540358

  13. Temporal trends and regional variations in gastrointestinal cancer mortality in Peru, 2005-2014.

    Science.gov (United States)

    Hernández-Vásquez, Akram; Bendezú-Quispe, Guido; Azañedo, Diego; Huarez, Bertha; Rodríguez-Lema, Belén

    2016-01-01

    To estimate and analyze the evolution of mortality rates of gastrointestinal (GI) cancer in Peru and its regions between 2005-2014. We performed a nationwide secondary analysis of Peru's Health Ministry registry of deaths during the period 2005-2014, with a focus on regional differences. Deaths registered with codes C15 to C25 (malignant neoplasms of digestive organs) from the ICD-10 were included. Calculation of age-standarized mortality rates and years of life lost (YLL) due to GI cancer per 100,000 habitants were also performed. Data of 67,527 deaths from GI cancers was analyzed, 35,055 (51.91%) were women. In 2005, the number of GI cancer deaths was 6,484, for 2014, 7,532 cases were recorded. The GI cancer age-standarized mortality rates at the country level showed a decrease of 12.70% between 2005-2014. Stomach cancer presented the highest age-standarized mortality rate despite showing a downward trend in the last years, equal for gallbladder, liver and biliary tract, and esophagus cancer. Colorectal, small intestine and anus cancer show a progressive increase. In 2014, Callao (48.8), Huancavelica (48.5), La Libertad (39.6), Lambayeque (40.5) and Huanuco (38.9) had the highest rates. The three types of GI cancers with the highest rates of YLL in 2014 were stomach cancer (118.51), followed by liver and biliary tract cancer (58.68) and colorectal (44.86). GI cancer mortality in Peru is high and a priority issue in regions like Huancavelica, Huanuco, Callao, La Libertad and Lambayeque. Stomach cancer remains the most frequent GI cancer, but with a downward trend in the study period.

  14. Trends in incidence, survival, and management of uveal melanoma: a population-based study of 7,516 patients from the Surveillance, Epidemiology, and End Results database (1973–2012

    Directory of Open Access Journals (Sweden)

    Mahendraraj K

    2016-10-01

    Full Text Available Krishnaraj Mahendraraj,1 Christine SM Lau,1,2 Injoon Lee,2 Ronald S Chamberlain1–3 1Department of Surgery, Saint Barnabas Medical Center, Livingston, NJ, USA; 2St George’s University School of Medicine, Grenada, West Indies; 3Department of Surgery, New Jersey Medical School, Rutgers University, Newark, NJ, USA Introduction: Uveal melanoma (UM is the most common primary intraocular malignancy, despite comprising <5% of all melanomas. To date, relatively few case series of UM have been published. Moreover, the factors influencing survival remain largely unknown. This study sought to analyze the impact of demographics, histology, clinical presentation, and treatments on the clinical outcomes of UM in a large modern nationwide patient cohort.Methods: Demographics and clinical data were abstracted on 277,120 histologically confirmed melanoma patients from the Surveillance, Epidemiology, and End Results database between 1973 and 2012.Results: A total of 7,516 cases of UM represented 3.2% of all recorded cases of melanoma. The mean age-adjusted incidence was 5.1 per million (95% CI 4.2–6.1 and was higher in males (5.9, CI =4.4–7.6 compared to females (4.5, CI =3.3–5.8, P<0.001. UM occurred most commonly in the sixth decade of life (61.4±15 and among Caucasians (94.7%. A total of 52.3% of cases were reported in the Western US (35.7% in California. The initial diagnoses in 65.2% of cases were by histopathology, followed by clinical diagnosis (18.8% and radiographic imaging (16.0%. The percentage of UM cases managed by surgery alone decreased by 69.4% between the 1973–1977 and 2006–2012 time periods, concomitant with a 62% increase in primary radiotherapy, P<0.001. The UM mean overall and cancer-specific 5-year relative survival rates were 79.8%±5.8% and 76%±5.3%, respectively. The mean 5-year cancer-specific survival rate (76% remained stable during the study period between 1973 and 2012. The mean survival for patients treated with

  15. Trends in spread of the particle therapy of cancers to areal bases

    International Nuclear Information System (INIS)

    Abe, Mitsuyuki; Aoki, Takashi; Tsujii, Hirohiko

    2009-01-01

    In Japan, the rate of cancer death accounts for 30%, now there are 8 facilities having the cancer particle therapy (PT) which is promising due to its highly effective, short term, non-surgical, not always expensive treatment, and local areas have tended to construct such facility for their people. This special article describes trends in the title concerning the areal intention for setting up the therapeutic bases, global trend of PT, research and development in manufacturers of PT equipments, and response of health insurer to the trend. The article contains following 15 topics presented by 15 authors or groups of the academia, official and company institutes, prefectural officers, manufacturers and an insurer, and by Editorial. Topics are: Significance and future view of PT in cancer treatment; Present state of construction of PT facilities in various areas; Fifteen year-results of PT in near-infrared spectroscopy (NIRS) and its effort to spread the therapy; Gumma University's 21st century program COE (Center of Excellence), Medical and Biological Studies with Accelerator Technology; Project for constructing Fukui Prefectural Proton PT Center; The role of Proton PT Center in southern Tohoku area as the first private facility; PT center by Foundation of Medipolis Medical Research Institute in southern Kyushu area; Global trend of PT; Spread of PT and the role of health insurance in it/Mitsui-Sumitomo's health insurance, Kirameki, the contribution to general public; Mitsubishi Electric Corp.'s effort to spread PT equipments; Toshiba's effort; Hitachi's effort; Sumitomo Heavy Industries' effort; Effort by Chiyoda Technol Corp. and Still River Systems to develop the next generation superconducting PT equipment; and Overview by Editorial/Complicated trend in invitation and construction of PT facilities. (K.T.)

  16. Landuse/Cover Change Trend in Soroti District Eastern Uganda ...

    African Journals Online (AJOL)

    This study assessed the extent and trend of landuse/cover change in Soroti District, Uganda. A series of systematically corrected Orthorectified Landsat imageries of 1973, 1986 and 2001 were downloaded from the Landsat website. The images were analysed using unsupervised classification approach and the land-use/ ...

  17. Trends in colorectal cancer incidence among younger adults-Disparities by age, sex, race, ethnicity, and subsite.

    Science.gov (United States)

    Crosbie, Amanda B; Roche, Lisa M; Johnson, Linda M; Pawlish, Karen S; Paddock, Lisa E; Stroup, Antoinette M

    2018-06-22

    Millennials (ages 18-35) are now the largest living generation in the US, making it important to understand and characterize the rising trend of colorectal cancer incidence in this population, as well as other younger generations of Americans. Data from the New Jersey State Cancer Registry (n = 181 909) and Surveillance, Epidemiology, and End Results program (n = 448 714) were used to analyze invasive CRC incidence trends from 1979 to 2014. Age, sex, race, ethnicity, subsite, and stage differences between younger adults (20-49) and screening age adults (≥50) in New Jersey (NJ) were examined using chi-square; and, we compared secular trends in NJ to the United States (US). Whites, men, and the youngest adults (ages 20-39) are experiencing greater APCs in rectal cancer incidence. Rates among younger black adults, overall, were consistently higher in both NJ and the US over time. When compared to older adults, younger adults with CRC in NJ were more likely to be: diagnosed at the late stage, diagnosed with rectal cancer, male, non-white, and Hispanic. Invasive CRC incidence trends among younger adults were found to vary by age, sex, race, ethnicity, and subsite. Large, case-level, studies are needed to understand the role of genetics, human papillomavirus (HPV), and cultural and behavioral factors in the rise of CRC among younger adults. Provider and public education about CRC risk factors will also be important for preventing and reversing the increasing CRC trend in younger adults. © 2018 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

  18. Trends in the incidence and mortality rates of malignant neoplasms in regions with radio ecological problems (Seslavtsi, Eleshnitsa, Yana) during the period 1995-1999

    International Nuclear Information System (INIS)

    Chobanova, N.; Yagova, A.; Bajrakova, A.

    2001-01-01

    A retrospective study is carried out to examine incidence and mortality trends of some malignant neoplasms in regions at high radioecological risk (Seslavtsi, Eleshnitsa, Yana) during the period 1995-1999. The analysis is made according to sex and age groups. Information sources are official medical statistics data, original records and database of the Oncological Dispensary in Sofia. The analysis of incidence and mortality dynamics doesn't show an increase in the incidence/mortality rate of the selected radiation-related oncological diseases compared with the same indices for the country within that period. (author)

  19. WATER TEMPERATURE and other data from BARTLETT in the NE Pacific from 1973-11-11 to 1973-12-16 (NCEI Accession 9500076)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data in this accession were collected in NE Pacific (limit-180) from USNS Bartlett between November 11, 1973 and December 16, 1973. The real time data of water...

  20. Imported malaria in Finland 1995 to 2008: an overview of surveillance, travel trends, and antimalarial drug sales.

    Science.gov (United States)

    Guedes, Sandra; Siikamäki, Heli; Kantele, Anu; Lyytikäinen, Outi

    2010-01-01

    To improve pre-travel advice, we analyzed nationwide population-based surveillance data on malaria cases reported to the National Infectious Disease Register of Finland (population 5.3 million) during 1995 to 2008 and related it to data on traveling and antimalarial drug sales. Surveillance data comprised information on malaria cases reported to the National Infectious Disease Register during 1995 to 2008. Traveling data were obtained from Statistics Finland (SF) and the Association of Finnish Travel Agents (AFTA). SF data included information on overnight leisure trips to malaria-endemic countries during 2000 to 2008. AFTA data included annual number of organized trips during 1999 to 2007. Quarterly numbers of antimalarial drug sales were obtained from the Finnish Medicines Agency. Descriptive and time series analyses were performed. A total of 484 malaria cases (average annual incidence 0.7/100,000 population) were reported; 283 patients were Finnish- and 201 foreign-born. In all, 15% of all cases were children; 72% foreign- and 28% Finnish-born. Malaria infections were mostly acquired in Africa (76%). Among foreign-born cases, 89% of the infections were acquired in the region of birth. The most common species were Plasmodium falciparum (61%) and Plasmodium vivax (22%). Although traveling to malaria-endemic areas increased, no increase occurred in malaria cases, and a decreasing trend was present in antimalarial drug sales. Traveling to malaria-endemic countries and drug sales followed the same seasonal pattern, with peaks in the first and last quarter of the year. More efforts should be focused on disseminating pre-travel advice to immigrants planning to visit friends and relatives and travelers on self-organized trips. © 2010 International Society of Travel Medicine.

  1. 21 CFR 184.1973 - Beeswax (yellow and white).

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Beeswax (yellow and white). 184.1973 Section 184.1973 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE...

  2. Mini-review of wind energy 1995

    International Nuclear Information System (INIS)

    1996-01-01

    At the 1995 meeting of the International Energy Agency CADDET renewable energy technologies programme, contributors aimed to advise on wind energy use and identify future needs for analysis of future trends and review research tasks. Three major trends leading to the commercial exploitation of wind energy are identified. Firstly, cost reduction and increased efficiency is aimed at through technical innovation, economies of scale and reduced labour costs. The environmental and social benefits of wind energy are acknowledged in the second place. Lastly, wind turbine deployment has been given decisive market incentives. Two major barriers block the development of the wind energy market, availability of site locations and the current economic state of countries likely to espouse wind energy. (UK)

  3. Progress report 1969-1973

    International Nuclear Information System (INIS)

    1974-01-01

    The most important experimental and theoretical results achieved by the scientific staff of the Prague ''Institute of Plasma Physics'' in the period 1969 to 1973 are reviewed. In the first place, results of investigation of high-frequency field-plasma interaction are presented, with the main accent to high-frequency plasma heating in open devices as well as in toroidal ones. Much attention is paid also to the experiment and theory of the nonlinear classical electron beam-plasma interaction. Especially, the unique agreement between numerical and experimental results concerning the electron trapping phenomena is demonstrated. Further, among others, the calibration procedure of a corpuscular diagnostic apparatus is described and some results concerning an experiment with rotating plasma in crossed fields are discussed. IPP CZ reports and an exhaustive bibliographic index of papers published in 1969 to 1973 are listed. (J.U.)

  4. Trends in lung cancer in elderly in Denmark, 1980-2012

    DEFF Research Database (Denmark)

    Kristiansen, Charlotte; Schytte, Tine; Holmskov, Karin

    2016-01-01

    1980. Due to the poor survival, similar trends were seen in mortality rates. Over the period, the one-year relative survival rates almost doubled in patients aged 70 years or more, but still only 25% of the patients aged 80-89 years survived their lung cancer for one year. Conclusion The incidence...... and methods Lung cancer was defined as ICD-10 codes C33-34. Data derived from the NORDCAN database with comparable data on cancer incidence, mortality, prevalence, and relative survival in the Nordic countries, where the Danish data were delivered from the Danish Cancer Registry and the Danish Cause of Death...... Registry with follow-up for death or emigration until the end of 2013. Results In 2012, about 50% of lung cancers were diagnosed among persons aged 70 years or more. For men and women older than 75 years the incidence rates have been increasing and for those aged 80-84 years, the rates have doubled since...

  5. Increase in breast cancer incidence among older women in Mumbai: 30-year trends and predictions to 2025.

    Science.gov (United States)

    Dikshit, Rajesh P; Yeole, B B; Nagrani, Rajini; Dhillon, P; Badwe, R; Bray, Freddie

    2012-08-01

    Increasing trends in the incidence of breast cancer have been observed in India, including Mumbai. These have likely stemmed from an increasing adoption of lifestyle factors more akin to those commonly observed in westernized countries. Analyses of breast cancer trends and corresponding estimation of the future burden are necessary to better plan rationale cancer control programmes within the country. We used data from the population-based Mumbai Cancer Registry to study time trends in breast cancer incidence rates 1976-2005 and stratified them according to younger (25-49) and older age group (50-74). Age-period-cohort models were fitted and the net drift used as a measure of the estimated annual percentage change (EAPC). Age-period-cohort models and population projections were used to predict the age-adjusted rates and number of breast cancer cases circa 2025. Breast cancer incidence increased significantly among older women over three decades (EAPC = 1.6%; 95% CI 1.1-2.0), while lesser but significant 1% increase in incidence among younger women was observed (EAPC = 1.0; 95% CI 0.2-1.8). Non-linear period and cohort effects were observed; a trends-based model predicted a close-to-doubling of incident cases by 2025 from 1300 mean cases per annum in 2001-2005 to over 2500 cases in 2021-2025. The incidence of breast cancer has increased in Mumbai during last two to three decades, with increases greater among older women. The number of breast cancer cases is predicted to double to over 2500 cases, the vast majority affecting older women. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. Gender differences in the trend of colorectal cancer incidence in Singapore, 1968–2002

    NARCIS (Netherlands)

    I.M.C.M. de Kok (Inge); C.S. Wong (Chia Siong); K.S. Chia (Kee Seng); X. Sim (Xueling); C.S. Tan (Chuen Seng); L.A.L.M. Kiemeney (Bart); H.M. Verkooijen (Helena)

    2008-01-01

    textabstractBackground and aims Over the past decades, incidence trends of colorectal cancer are sharply increased in Singapore. In this population-based study we describe changes in colorectal cancer incidence in Singapore and explore the reasons behind these changes through age-period cohort

  7. Impact of national cancer policies on cancer survival trends and socioeconomic inequalities in England, 1996-2013: population based study.

    Science.gov (United States)

    Exarchakou, Aimilia; Rachet, Bernard; Belot, Aurélien; Maringe, Camille; Coleman, Michel P

    2018-03-14

    To assess the effectiveness of the NHS Cancer Plan (2000) and subsequent national cancer policy initiatives in improving cancer survival and reducing socioeconomic inequalities in survival in England. Population based cohort study. England. More than 3.5 million registered patients aged 15-99 with a diagnosis of one of the 24 most common primary, malignant, invasive neoplasms between 1996 and 2013. Age standardised net survival estimates by cancer, sex, year, and deprivation group. These estimates were modelled using regression model with splines to explore changes in the cancer survival trends and in the socioeconomic inequalities in survival. One year net survival improved steadily from 1996 for 26 of 41 sex-cancer combinations studied, and only from 2001 or 2006 for four cancers. Trends in survival accelerated after 2006 for five cancers. The deprivation gap observed for all 41 sex-cancer combinations among patients with a diagnosis in 1996 persisted until 2013. However, the gap slightly decreased for six cancers among men for which one year survival was more than 65% in 1996, and for cervical and uterine cancers, for which survival was more than 75% in 1996. The deprivation gap widened notably for brain tumours in men and for lung cancer in women. Little evidence was found of a direct impact of national cancer strategies on one year survival, and no evidence for a reduction in socioeconomic inequalities in cancer survival. These findings emphasise that socioeconomic inequalities in survival remain a major public health problem for a healthcare system founded on equity. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  8. National, regional, and worldwide estimates of stillbirth rates in 2009 with trends since 1995: a systematic analysis.

    Science.gov (United States)

    Cousens, Simon; Blencowe, Hannah; Stanton, Cynthia; Chou, Doris; Ahmed, Saifuddin; Steinhardt, Laura; Creanga, Andreea A; Tunçalp, Ozge; Balsara, Zohra Patel; Gupta, Shivam; Say, Lale; Lawn, Joy E

    2011-04-16

    Stillbirths do not count in routine worldwide data-collating systems or for the Millennium Development Goals. Two sets of national stillbirth estimates for 2000 produced similar worldwide totals of 3·2 million and 3·3 million, but rates differed substantially for some countries. We aimed to develop more reliable estimates and a time series from 1995 for 193 countries, by increasing input data, using recent data, and applying improved modelling approaches. For international comparison, stillbirth is defined as fetal death in the third trimester (≥1000 g birthweight or ≥28 completed weeks of gestation). Several sources of stillbirth data were identified and assessed against prespecified inclusion criteria: vital registration data; nationally representative surveys; and published studies identified through systematic literature searches, unpublished studies, and national data identified through a WHO country consultation process. For 2009, reported rates were used for 33 countries and model-based estimates for 160 countries. A regression model of log stillbirth rate was developed and used to predict national stillbirth rates from 1995 to 2009. Uncertainty ranges were obtained with a bootstrap approach. The final model included log(neonatal mortality rate) (cubic spline), log(low birthweight rate) (cubic spline), log(gross national income purchasing power parity) (cubic spline), region, type of data source, and definition of stillbirth. Vital registration data from 79 countries, 69 nationally representative surveys from 39 countries, and 113 studies from 42 countries met inclusion criteria. The estimated number of global stillbirths was 2·64 million (uncertainty range 2·14 million to 3·82 million) in 2009 compared with 3·03 million (uncertainty range 2·37 million to 4·19 million) in 1995. Worldwide stillbirth rate has declined by 14·5%, from 22·1 stillbirths per 1000 births in 1995 to 18·9 stillbirths per 1000 births in 2009. In 2009, 76·2% of

  9. Trends in breast cancer in the elderly in Denmark, 1980-2012

    DEFF Research Database (Denmark)

    Jensen, Jeanette D; Cold, Søren; Holck Nielsen, Mette

    2016-01-01

    over time in all age groups, but patients aged 70 years or more had a poorer relative survival than those aged less than 70 years. In 2012, 58 521 persons (all ages) were alive in Denmark after a diagnosis of breast cancer. Conclusion Poorer survival of Danish breast cancer patients over the age of 70......Background Breast cancer is the most frequent malignancy among women worldwide and the second most common cause of cancer-related death in developed countries. The aim of the present analysis is to describe trends in incidence, mortality, prevalence, and relative survival in Denmark from 1980...... to 2012 focusing on age, comparing persons aged 70 years or more with those aged less than 70 years. Material and methods Cancer of the breast was defined as ICD-10 code C50. Data derived from the NORDCAN database with comparable data on cancer incidence, mortality, prevalence and relative survival...

  10. Timber resource statistics for Washington, January 1, 1973.

    Science.gov (United States)

    Patricia M. Bassett; Grover A. Choate

    1974-01-01

    Timber resource statistics to January 1, 1973, for the State of Washington show total land area, commercial timberland area, and growing stock and sawtimber inventory volumes by county and owner group. Growth and removals are shown by Forest Survey inventory unit for 1972. Each National Forest is updated to January 1, 1973.

  11. International testicular cancer incidence trends: generational transitions in 38 countries 1900-1990.

    Science.gov (United States)

    Znaor, Ariana; Lortet-Tieulent, Joannie; Laversanne, Mathieu; Jemal, Ahmedin; Bray, Freddie

    2015-01-01

    Rapid increases in testicular cancer incidence have marked the second half of the last century. While these secular rises, observed mainly in countries attaining the highest levels of human development, appear to have attenuated in the last decade, rates continue to increase in countries transiting toward high developmental levels. The purpose of our study was to provide a comprehensive analysis and presentation of the cohort-specific trends in testicular cancer incidence rates in 38 countries worldwide. We used an augmented version of the Cancer Incidence in Five Continents series to analyze testicular cancer incidence in men aged 15-54 in 38 countries, via age-period-cohort analysis. In many European countries, the USA, Canada, Australia, and New Zealand, there is a continuation of the increasing risk among successive generations, yet rates are attenuating in male cohorts born since the 1970s in several Northern European countries, in contrast to the steeply increasing trends in recent cohorts in Southern Europe. Incidence rates have also been increasing in the populations traditionally at rather low risk, such as in the Philippines, Singapore, China, and Costa Rica. The attenuation of testicular cancer risk in younger generations (in the most developed countries) alongside concomitant increases (in countries undergoing developmental change) is indicative of a global transition in the risk of testicular cancer. While identifying the underlying causes remains a major challenge, increasing awareness and adapting national healthcare systems to accommodate a growing burden of testicular cancer may prevent future avoidable deaths in young men.

  12. Contraceptive sterilization among Canadians, 1984-1995

    Directory of Open Access Journals (Sweden)

    Vijaya Krishnan

    2004-12-01

    Full Text Available Prior to early 1970s, traditional methods were the principal means of controlling the number and spacing of births. Today, an estimated 57 per cent of the world’s married women use contraceptives and half use modern methods such as medical sterilizations. Recent statistics suggest that Canada has the highest sterilization rate in the Western world. This paper presents findings of research examining sterilization trends in Canada with respect to changing patterns in the use of modern contraceptives, using data from the 1984 Canadian Fertility Survey (CFS and the 1995 General Social Survey (GSS. The main finding is that there is a decrease in the use of tubal ligation and an increase in the use of hysterectomy over the period 1984-1995. Less educated women are more likely to be in the forefront of modern methods of contraception.

  13. New insights into survival trend analyses in cancer population-based studies: the SUDCAN methodology.

    Science.gov (United States)

    Uhry, Zoé; Bossard, Nadine; Remontet, Laurent; Iwaz, Jean; Roche, Laurent

    2017-01-01

    The main objective of the SUDCAN study was to compare, for 15 cancer sites, the trends in net survival and excess mortality rates from cancer 5 years after diagnosis between six European Latin countries (Belgium, France, Italy, Portugal, Spain and Switzerland). The data were extracted from the EUROCARE-5 database. The study period ranged from 6 (Portugal, 2000-2005) to 18 years (Switzerland, 1989-2007). Trend analyses were carried out separately for each country and cancer site; the number of cases ranged from 1500 to 104 000 cases. We developed an original flexible excess rate modelling strategy that accounts for the continuous effects of age, year of diagnosis, time since diagnosis and their interactions. Nineteen models were constructed; they differed in the modelling of the effect of the year of diagnosis in terms of linearity, proportionality and interaction with age. The final model was chosen according to the Akaike Information Criterion. The fit was assessed graphically by comparing model estimates versus nonparametric (Pohar-Perme) net survival estimates. Out of the 90 analyses carried out, the effect of the year of diagnosis on the excess mortality rate depended on age in 61 and was nonproportional in 64; it was nonlinear in 27 out of the 75 analyses where this effect was considered. The model fit was overall satisfactory. We analysed successfully 15 cancer sites in six countries. The refined methodology proved necessary for detailed trend analyses. It is hoped that three-dimensional parametric modelling will be used more widely in net survival trend studies as it has major advantages over stratified analyses.

  14. Trends in Media Reports of Celebrities' Breast Cancer Treatment Decisions.

    Science.gov (United States)

    Sabel, Michael S; Dal Cin, Sonya

    2016-09-01

    Although the increasing use of bilateral mastectomies is multifaceted, one source of influence may be the media, including coverage of celebrity breast cancer treatment. We examined trends in media reporting that might impact decision making among women with breast cancer. We performed searches of two comprehensive online databases for articles from major U.S. print publications mentioning celebrities and terms related to the word "breast" and terms related to cancer treatment. Automated analysis using custom-created dictionaries was used to determine word frequencies over time. An analysis of net media tone was conducted using Lexicoder Sentiment Dictionaries. Celebrity breast cancer media reports significantly increased since 2004 (p celebrity had bilateral mastectomies than unilateral mastectomy or breast conservation (44.8 vs 26.1 %, p celebrities undergoing bilateral mastectomy for cancer had no mention of genetics, family history, or risk. Media reports of celebrity breast cancer present a bias toward bilateral mastectomies in both frequency and tone. This may sway public opinion, particularly when factors such as risk and genetics are excluded. Surgeons need to work with the media to improve cancer reporting and identify methods to better educate patients prior to surgical consultations.

  15. Research report 1973

    International Nuclear Information System (INIS)

    The scientific progress achieved in 1973 is reported in 29 contributions. The main problems are: a) plasma heating and waves, b) plasma focus and shock wave investigations, c) short-time technique and d) laser applications in plasma diagnostics. Furthermore, the report contains an index of the scientific reports, publications, lectures and dissertations in the period under review. (GG/LH) [de

  16. The end of the decline in cervical cancer mortality in Spain: trends across the period 1981-2012.

    Science.gov (United States)

    Cervantes-Amat, Marta; López-Abente, Gonzalo; Aragonés, Nuria; Pollán, Marina; Pastor-Barriuso, Roberto; Pérez-Gómez, Beatriz

    2015-04-15

    In Spain, cervical cancer prevention is based on opportunistic screening, due to the disease's traditionally low incidence and mortality rates. Changes in sexual behaviour, tourism and migration have, however, modified the probability of exposure to human papilloma virus among Spaniards. This study thus sought to evaluate recent cervical cancer mortality trends in Spain. We used annual female population figures and individual records of deaths certified as cancer of cervix, reclassifying deaths recorded as unspecified uterine cancer to correct coding quality problems. Joinpoint models were fitted to estimate change points in trends, as well as the annual (APC) and average annual percentage change. Log-linear Poisson models were also used to study age-period-cohort effects on mortality trends and their change points. 1981 marked the beginning of a decline in cervical cancer mortality (APC(1981-2003): -3.2; 95% CI:-3.4;-3.0) that ended in 2003, with rates reaching a plateau in the last decade (APC2003-2012: 0.1; 95% CI:-0.9; 1.2). This trend, which was observable among women aged 45-46 years (APC(2003-2012): 1.4; 95% CI:-0.1;2.9) and over 65 years (APC(2003-2012): -0.1; 95% CI:-1.9;1.7), was clearest in Spain's Mediterranean and Southern regions. The positive influence of opportunistic screening is not strong enough to further reduce cervical cancer mortality rates in the country. Our results suggest that the Spanish Health Authorities should reform current prevention programmes and surveillance strategies in order to confront the challenges posed by cervical cancer.

  17. Prevalence and trends in breast cancer in Lagos state, Nigeria ...

    African Journals Online (AJOL)

    The study examined the trends in the prevalence of breast cancer in Lagos State, Nigeria. A sample of 1000 subjects was taken from a population consisting of women between the ages of 15 and 60 years spread across the 20 Local Government Areas (LGAs) of the State. Fifty questionnaires were distributed in each LGA.

  18. Trends in compensation for deaths from occupational cancer in Canada: a descriptive study.

    Science.gov (United States)

    Del Bianco, Ann; Demers, Paul A

    2013-09-01

    Occupational cancer is the leading cause of work-related deaths, yet it is often unrecognized and under reported, and associated claims for compensation go unfiled. We sought to examine trends in deaths from occupational cancer, high-risk industries and exposures, and commonly compensated categories of occupational cancers. In addition, we compared deaths from occupational lung cancer for which compensation had been given with total deaths from lung cancer. We used data from the Association of Workers' Compensation Boards of Canada pertaining to the nature and source of the injury or disease and the industry in which it occurred (by jurisdiction) to describe trends in compensated claims for deaths from occupational cancer in Canada for the period 1997-2010. We used data published by the Canadian Cancer Society in Canadian Cancer Statistics to compare compensated occupational lung cancer deaths with total estimated lung cancer deaths for the period between 2006 and 2010. Compensated claims for deaths from occupational cancer have increased in recent years and surpassed those for traumatic injuries and disorders in Canada, particularly in Ontario. Between 1997 and 2010, one-half of all compensated deaths from occupational cancer in Canada were from Ontario. High-risk industries for occupational cancer include manufacturing, construction, mining and, more recently, government services. Deaths from lung cancer and mesothelioma comprise most of the compensated claims for deaths from occupational cancer in Ontario and Canada. These diseases are usually the result of asbestos exposure. The burden of other occupational carcinogens is not reflected in claims data. Although the number of accepted claims for deaths from occupational cancers has increased in recent years, these claims likely only represent a fraction of the true burden of this problem. Increased education of patients, workers at high risk of exposure and health care providers is needed to ensure that people

  19. HIV Care in the Swedish-Danish HIV Cohort 1995-2010

    DEFF Research Database (Denmark)

    Helleberg, Marie; Häggblom, Amanda; Sönnerborg, Anders

    2013-01-01

    Successful treatment reduces morbidity, mortality and transmission of HIV. We evaluated trends in the treatment status of HIV infected individuals enrolled in care in Sweden and Denmark during the years 1995-2010. Our aim was to assess the proportion of HIV-infected individuals who received...

  20. US Department of Energy Portsmouth. Annual environmental report for 1995

    International Nuclear Information System (INIS)

    1997-04-01

    This report summarizes the 1995 environmental monitoring of DOE activities at the Portsmouth Gaseous Diffusion Plant and its environs. This report consists of two separate documents: a discussion of compliance status, data, and environmental impacts (this document); and a volume of detailed data that is available on request. The objectives of this report are to (1) report compliance status during 1995, (2) provide information about the site and DOE operations, (3) report 1995 monitoring data for the installation and its environs that may have been affected by DOE operations on the site, (4) document information on input and assumptions used in calculations, (5) provide trend analyses (where appropriate) to indicate increases and decreases in environmental impact, and (6) provide general information on quality assurance for the environmental monitoring program for DOE operations

  1. US Department of Energy Portsmouth. Annual environmental report for 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    This report summarizes the 1995 environmental monitoring of DOE activities at the Portsmouth Gaseous Diffusion Plant and its environs. This report consists of two separate documents: a discussion of compliance status, data, and environmental impacts (this document); and a volume of detailed data that is available on request. The objectives of this report are to (1) report compliance status during 1995, (2) provide information about the site and DOE operations, (3) report 1995 monitoring data for the installation and its environs that may have been affected by DOE operations on the site, (4) document information on input and assumptions used in calculations, (5) provide trend analyses (where appropriate) to indicate increases and decreases in environmental impact, and (6) provide general information on quality assurance for the environmental monitoring program for DOE operations.

  2. Trends in presentation, management and survival of patients with de novo metastatic breast cancer in a Southeast Asian setting

    NARCIS (Netherlands)

    Bhoo Pathy, Nirmala; Verkooijen, Helena Marieke; Tan, Ern-Yu; Miao, Hui; Taib, Nur Aishah Mohd; Brand, Judith S.; Dent, Rebecca A.; See, Mee-Hoong; Subramaniam, ShriDevi; Chan, Patrick; Lee, Soo-Chin; Hartman, Mikael; Yip, Cheng-Har

    2015-01-01

    Up to 25% of breast cancer patients in Asia present with de novo metastatic disease. We examined the survival trends of Asian patients with metastatic breast cancer over fifteen years. The impact of changes in patient's demography, tumor characteristics, tumor burden, and treatment on survival trend

  3. Environmental surveillance at Los Alamos during 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    This report describes the environmental surveillance program at Los Alamos National Laboratory (LANL or the Laboratory) during 1995. The Laboratory routinely monitors for radiation and for radioactive and nonradioactive materials at (or on) Laboratory sites as well as in the surrounding region. LANL uses the monitoring result to determine compliance with appropriate standards and to identify potentially undesirable trends. Data were collected in 1995 to assess external penetrating radiation; quantities of airborne emissions and liquid effluents; concentrations of chemicals and radionuclides in ambient air, surface waters and groundwaters, municipal water supply, soils and sediments, and foodstuffs; and environmental compliance. Using comparisons with standards, regulations, and background levels, this report concludes that environmental effects from Laboratory operations are small and do not pose a demonstrable threat to the public, Laboratory employees, or the environment.

  4. Environmental surveillance at Los Alamos during 1995

    International Nuclear Information System (INIS)

    1996-10-01

    This report describes the environmental surveillance program at Los Alamos National Laboratory (LANL or the Laboratory) during 1995. The Laboratory routinely monitors for radiation and for radioactive and nonradioactive materials at (or on) Laboratory sites as well as in the surrounding region. LANL uses the monitoring result to determine compliance with appropriate standards and to identify potentially undesirable trends. Data were collected in 1995 to assess external penetrating radiation; quantities of airborne emissions and liquid effluents; concentrations of chemicals and radionuclides in ambient air, surface waters and groundwaters, municipal water supply, soils and sediments, and foodstuffs; and environmental compliance. Using comparisons with standards, regulations, and background levels, this report concludes that environmental effects from Laboratory operations are small and do not pose a demonstrable threat to the public, Laboratory employees, or the environment

  5. 1995 NPTS Databook

    Energy Technology Data Exchange (ETDEWEB)

    Hu, PS

    2001-12-05

    Policymakers rely on transportation statistics, including data on personal travel behavior, to formulate strategic transportation policies and to improve the safety and efficiency of the U.S. transportation system. Data on personal travel trends are needed to examine the reliability, efficiency, capacity, and flexibility of the Nation's transportation system to meet current demands and accommodate future demands; to assess the feasibility and efficiency of alternative congestion-alleviating technologies (e.g., high-speed rail, magnetically levitated trains, intelligent vehicle and highway systems); to evaluate the merits of alternative transportation investment programs; and to assess the energy-use and air-quality impacts of various policies. To address these data needs, the Department of Transportation (DOT) initiated an effort in 1969 to collect detailed data on personal travel. The 1969 survey was the first Nationwide Personal Transportation Survey (NPTS). The survey was conducted again in 1977, 1983, 1990, and 1995. The 1995 survey was cosponsored by four DOT agencies: Federal Highway Administration (FHWA), Bureau of Transportation Statistics (BTS), Federal Transit Administration (FTA), and National Highway Traffic Safety Administration (NHTSA). The primary objective of the survey was to collect trip-based data on the nature and characteristics of personal travel. Commercial and institutional travel were not part of the survey.

  6. Epidemiology and trend of common cancers in Iran (2004-2008).

    Science.gov (United States)

    Amori, N; Aghajani, M; Asgarian, F S; Jazayeri, M

    2017-09-01

    Cancer is one of the most important causes of mortality worldwide. It includes approximately 13% of death cases. This study aimed to investigate the incidence trend of common cancers in Iran during 2004-2008 to improve reporting distribution the disease. This was a retrospective study. The study population was all cases of cancer diagnosed in Iran during 2004-2008. The crude incidence rate of cancers was calculated per 100 000 people by age groups and sex. Age-standardised incidence rates (ASRs) were calculated using direct standardisation and the world standard population. Data were analysed using SPSS (version 17) and Microsoft Office Excel 2007. In this study, a total of 301 055 cases of cancer were diagnosed. ASRs were 60.51 and 84.51 in women and men respectively. Most common cancers in men were skin (ASR = 18.85), stomach (15.02), bladder (ASR = 11.25), prostate (ASR = 8.93) and colorectal (ASR = 8.29). Most common cancers in women were breast (ASR = 18.24), skin (ASR = 12.01), colorectal (ASR = 7.75), stomach (ASR = 7.05) and haematocyte (ASR = 4.01). A significant increase was observed in the incidence of cancers in the country. Therefore, it is necessary to perform screening, early diagnosis and treatment in early stages of cancers. © 2016 John Wiley & Sons Ltd.

  7. Timber resource statistics for Oregon, January 1, 1973.

    Science.gov (United States)

    Patricia M. Bassett; Grover A. Choate

    1974-01-01

    Timber resource statistics as of January 1, 1973, for the State of Oregon show total land area, commercial timberland area, and growing stock and sawtimber inventory volumes by county and owner group. Growth and removals are shown by Forest Survey inventory unit for 1972. Each National Forest is updated to January 1, 1973, as well as each Bureau of Land Management...

  8. Trends in incidence of lung cancer in Croatia from 2001 to 2013: gender and regional differences.

    Science.gov (United States)

    Siroglavić, Katarina Josipa; Polić Vižintin, Marina; Tripković, Ingrid; Šekerija, Mario; Kukulj, Suzana

    2017-10-31

    To provide an overview of the lung cancer incidence trends in the City of Zagreb (Zagreb), Split-Dalmatia County (SDC), and Croatia in the period from 2001 to 2013. Incidence data were obtained from the Croatian National Cancer Registry. For calculating incidence rates per 100 000 population, we used population estimates for the period 2001-2013 from the Croatian Bureau of Statistics. Age-standardized rates of lung cancer incidence were calculated by the direct standardization method using the European Standard Population. To describe incidence trends, we used joinpoint regression analysis. Joinpoint analysis showed a statistically significant decrease in lung cancer incidence in men in all regions, with an annual percentage change (APC) of -2.2% for Croatia, 1.9% for Zagreb, and -2.0% for SDC. In women, joinpoint analysis showed a statistically significant increase in the incidence for Croatia, with APC of 1.4%, a statistically significant increase of 1.0% for Zagreb, and no significant change in trend for SDC. In both genders, joinpoint analysis showed a significant decrease in age-standardized incidence rates of lung cancer, with APC of -1.3% for Croatia, -1.1% for Zagreb, and -1.6% for SDC. There was an increase in female lung cancer incidence rate and a decrease in male lung cancer incidence rate in Croatia in 2001-20013 period, with similar patterns observed in all the investigated regions. These results highlight the importance of smoking prevention and cessation policies, especially among women and young people.

  9. Regional differences in incidence of gastric and colonic cancer in the Maori of New Zealand

    Science.gov (United States)

    Thompson, A

    2002-01-01

    Background: It is known that there are ethnic differences in cancer in New Zealand between Maori (the indigenous people) and non-Maori, however, until now no regional comparisons have been made. Study design: A retrospective study of patients diagnosed at Whangarei Hospital, New Zealand between 1995 and 1997 with gastric or colonic cancer was combined with population data from the 1996 census for Whangarei District to calculate incidence figures. The incidence of cancer was compared to national rates. Results: Between 1995 and 1997, 19 Maori and 24 non-Maori were diagnosed with gastric cancer, and 10 Maori and 125 non-Maori with colonic cancer. The age standardised rates (per 100 000) for Maori and non-Maori with gastric caner were 68.3 and 7.9 respectively. Gastric cancer is known to be increased in the Maori, but in Whangarei was significantly higher than the national Maori rates (20.5). There was no difference in the rate of colonic cancer in the Maori and non-Maori in Whangarei, again this differs from the national trends, in which the Maori are protected against cancer. Conclusion: This study highlights that there is still much more to be learnt in understanding the aetiology of gastrointestinal cancers, to explain such strong regional differences. PMID:12151659

  10. Patterns of Radiotherapy Practice for Patients With Cervical Cancer in Japan, 2003-2005: Changing Trends in the Pattern of Care Process

    Energy Technology Data Exchange (ETDEWEB)

    Tomita, Natsuo, E-mail: ntomita@aichi-cc.jp [Department of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya (Japan); Toita, Takafumi [Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, Okinawa (Japan); Kodaira, Takeshi [Department of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya (Japan); Shinoda, Atsunori [Department of Radiology, Shinshu University School of Medicine, Matsumoto (Japan); Uno, Takashi [Department of Radiology, Graduate School of Medicine, Chiba University, Chiba (Japan); Numasaki, Hodaka; Teshima, Teruki [Department of Medical Physics and Engineering, Graduate School of Medicine, Osaka University, Suita (Japan); Mitsumori, Michihide [Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto (Japan)

    2012-08-01

    Purpose: The patterns of care study (PCS) of radiotherapy for cervical cancer in Japan over the last 10 years was reviewed. Methods and Materials: The Japanese PCS working group analyzed data from 1,200 patients (1995-1997, 591 patients; 1999-2001, 324 patients; 2003-2005, 285 patients) with cervical cancer treated with definitive radiotherapy in Japan. Results: Patients in the 2001-2003 survey were significantly younger than those in the 1999-2001 study (p < 0.0001). Histology, performance status, and International Federation of Gynecology and Obstetrics stage were not significantly different among the three survey periods. Use of combinations of chemotherapy has increased significantly during those periods (1995-1997, 24%; 1999-2001, 33%; 2003-2005, 54%; p < 0.0001). The ratio of patients receiving concurrent chemotherapy has also dramatically increased (1995-1997, 20%; 1999-2001, 54%; 2003-2005, 83%; p < 0.0001). As for external beam radiotherapy (EBRT), the application rate of four-field portals has greatly increased over the three survey periods (1995-1997, 2%; 1999-2001, 7%; 2003-2005, 21%; p < 0.0001). In addition, the use of an appropriate beam energy for EBRT has shown an increase (1995-1997, 67%; 1999-2001, 74%; 2003-2005, 81%; p = 0.064). As for intracavitary brachytherapy (ICBT), an iridium source has become increasingly popular (1995-1997, 27%; 1999-2001, 42%; 2003-2005, 84%; p < 0.0001). Among the three surveys, the ratio of patients receiving ICBT (1995-1997, 77%; 1999-2001, 82%; 2003-2005, 78%) has not changed. Although follow-up was inadequate in each survey, no significant survival differences were observed (p = 0.36), and rates of late Grade 3 or higher toxicity were significantly different (p = 0.016). Conclusions: The Japanese PCS has monitored consistent improvements over the past 10 years in the application of chemotherapy, timing of chemotherapy, and EBRT methods. However, there is still room for improvement, especially in the clinical

  11. Worldwide trends in gastric cancer mortality (1980-2011), with predictions to 2015, and incidence by subtype.

    Science.gov (United States)

    Ferro, Ana; Peleteiro, Bárbara; Malvezzi, Matteo; Bosetti, Cristina; Bertuccio, Paola; Levi, Fabio; Negri, Eva; La Vecchia, Carlo; Lunet, Nuno

    2014-05-01

    Gastric cancer incidence and mortality decreased substantially over the last decades in most countries worldwide, with differences in the trends and distribution of the main topographies across regions. To monitor recent mortality trends (1980-2011) and to compute short-term predictions (2015) of gastric cancer mortality in selected countries worldwide, we analysed mortality data provided by the World Health Organization. We also analysed incidence of cardia and non-cardia cancers using data from Cancer Incidence in Five Continents (2003-2007). The joinpoint regression over the most recent calendar periods gave estimated annual percent changes (EAPC) around -3% for the European Union (EU) and major European countries, as well as in Japan and Korea, and around -2% in North America and major Latin American countries. In the United States of America (USA), EU and other major countries worldwide, the EAPC, however, were lower than in previous years. The predictions for 2015 show that a levelling off of rates is expected in the USA and a few other countries. The relative contribution of cardia and non-cardia gastric cancers to the overall number of cases varies widely, with a generally higher proportion of cardia cancers in countries with lower gastric cancer incidence and mortality rates (e.g. the USA, Canada and Denmark). Despite the favourable mortality trends worldwide, in some countries the declines are becoming less marked. There still is the need to control Helicobacter pylori infection and other risk factors, as well as to improve diagnosis and management, to further reduce the burden of gastric cancer. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Colorectal cancer incidence, mortality and survival in Cali, Colombia, 1962-2012

    Directory of Open Access Journals (Sweden)

    Armando Cortés

    2014-08-01

    Full Text Available Objective. To study the colorectal cancer (CRC behavior in Cali, Colombia, during the 1963-2012 period using data from the Population-based Cancer Registry of Cali and the Municipal Health Secretariat of Cali. Materials and methods. An ecological time series analysis to study the CRC incidence (1962-2007 and mortality (1984-2012 rate trends; and a survival analysis of CRC cases registered in Cali between 1995 and 2004 were conducted. The age-standardized temporal trend of incidence (I-ASR and mortality (M-ASR rates were studied using an annual percent change (APC. The 5-year relative survival was estimated and a multivariate analysis was performed using the Cox proportional hazard regression model. Results. During the 1962-2007 period, CRC TTIR increased in men and women living in Cali [APC= 2.6 (95% CI 2.2-3.0 and APC= 2.2% (95% CI 1.8-2.7, respectively]. In the 1984-2012 period, the TTMR remained stable in women but increased in men in all age groups [APC= 1.8 (95% CI 0.8-2.8]. The 5-year relative survival was independent of sex and increased from 29.7% in 1995-1999 to 39.8% in 2000- 2004. The risk of dying from CRC was higher in people of lower socio-economic status (SES vs higher SES [HR= 2.1 (95% CI: 1.7-2.6], among people older than 70 years of age vs younger than 50 years [HR= 2.4 (95% CI: 1.9-2.9], and for the 1995-1999 period vs 2000-2004 period [HR= 1.5(95% CI 1.3-1.7]. Conclusion. CRC is beginning to take a prominent place among the most important cancers in Cali, Colombia.

  13. Trends in socioeconomic inequalities in oral health among 15-year-old Danish adolescents during 1995-2013: A nationwide, register-based, repeated cross-sectional study.

    Science.gov (United States)

    Sengupta, Kaushik; Christensen, Lisa Bøge; Mortensen, Laust Hvas; Skovgaard, Lene Theil; Andersen, Ingelise

    2017-10-01

    Scandinavian welfare states, despite having better population oral health than less egalitarian societies, are characterized by ubiquitous social gradients and large relative socioeconomic inequalities in oral health. However, trends in these inequalities among Scandinavian children and adolescents have not been studied in detail. To describe the associations between socioeconomic position (SEP) and oral health in adolescents and to investigate the trends in these associations between 1995 and 2013. Nationwide repeated cross-sectional studies (using individual-level data) were conducted on 15-year-olds in Denmark from 1995, 2003, and 2013 (N=154,750). Dental data were obtained from the national dental register of the Danish Health Authority (Sundhedsstyrelsens Centrale Odontologiske Register [SCOR]) and data on social variables from administrative registers at Statistics Denmark. SEP measures included previous year's parental education (highest attained educational level by either of the parents), income (equivalized household disposable income), and occupational social class (highest recorded occupational class between the parents). Covariates were immigration status, country of origin, number of children and persons in the family, and household type. The outcome was dental caries experience, represented by the decayed, missing, and filled surfaces (DMFS) index. Negative binomial regression models were used to examine the association between DMFS count and each of the explanatory variables separately while accounting for cluster-correlated family data. Furthermore, hierarchical multiple regressions of DMFS on SEP indicators-using the zero-inflated negative binomial (ZINB) distribution as the outcome distribution-were estimated while successively adjusting for the potential effects of the included covariates. Caries prevalence declined from 71% in 1995 to 63% in 2003 and 45% in 2013. Separate assessment of each covariate showed statistically significant graded

  14. Trend of oral and pharyngeal cancer mortality in Brazil in the period of 2002 to 2013

    Science.gov (United States)

    Perea, Lillia Magali Estrada; Peres, Marco Aurélio; Boing, Antonio Fernando; Antunes, José Leopoldo Ferreira

    2018-01-01

    ABSTRACT OBJECTIVE To analyze the trend of oral and pharyngeal cancer mortality rates in the period of 2002 to 2013 in Brazil according to sex, anatomical site, and macroregion of the country. METHODS The mortality data were obtained from the Mortality Information System and the population data were obtained from the Brazilian Institute of Geography and Statistics. The trend of the rates standardized by sex and age was calculated using the Prais-Winsten estimation, and we obtained the annual percentage change and the respective 95% confidence intervals, analyzed according to sex, macroregion, and anatomical site. RESULTS The average coefficient of oral cancer mortality was 1.87 per 100,000 inhabitants and it remained stable during the study period. The coefficient of pharyngeal cancer mortality was 2.04 per 100,000 inhabitants and it presented an annual percentage change of -2.6%. Approximately eight in every 10 deaths occurred among men. There was an increase in the rates of oral cancer in the Northeast region (annual percentage change of 6.9%) and a decrease in the Southeast region (annual percentage change of -2.9%). Pharyngeal cancer mortality decreased in the Southeast and South regions with annual percentage change of -4.8% and -5.1% respectively. Cancer mortality for tonsil, other major salivary glands, hypopharynx, and other and unspecified parts of mouth and pharynx showed a decreasing trend while the other sites presented stability. CONCLUSIONS Pharyngeal cancer mortality decreased in the period of 2002 to 2013. Oral cancer increased only in the Northeast region. Mortality for tonsil cancer, other major salivary glands, hypopharynx, and other and ill-defined sites in the lip, oral cavity, and pharynx decreased. PMID:29412371

  15. A Bibliometric Analysis of Research on Supported Ionic Liquid Membranes during the 1995–2015 Period: Study of the Main Applications and Trending Topics

    Directory of Open Access Journals (Sweden)

    Ricardo Abejón

    2017-11-01

    Full Text Available A bibliometric analysis based on Scopus database was performed to identify the global research trends related to Supported Ionic Liquid Membranes (SILMs during the time period from 1995 to 2015. This work tries to improve the understanding of the most relevant research topics and applications. The results from the analysis reveal that only after 2005 the research efforts focused on SILMs became significant, since the references found before that year are scarce. The most important research works on the four main application groups for SILMs defined in this work (carbon dioxide separation, other gas phase separations, pervaporation and liquid phase separations were summarized in this paper. Carbon dioxide separation appeared as the application that has received by far the most attention according to the research trends during the analysed period. Comments about other significant applications that are gaining attention, such as the employment of SILMs in analytical tasks or their consideration for the production of fuel cells, have been included.

  16. Cancer Incidence Trend in the Hebei Spirit Oil Spill Area, from 1999 to 2014: An Ecological Study.

    Science.gov (United States)

    Choi, Kyung-Hwa; Park, Myung-Sook; Ha, Mina; Hur, Jong-Il; Cheong, Hae-Kwan

    2018-05-17

    The Hebei Spirit oil spill (HSOS) occurred in the Republic of Korea on 7 December 2007. We aimed to describe the cancer incidence trend in Taean County before and after the oil spill. Five major cancers and leukemia were analyzed. Cancer incidence data were obtained from the Korean National Cancer Center. We compared the standardized incidence rates in Taean with those observed nationwide and selected three coastal areas. Joinpoint regression analysis was used to examine the trends in the average annual percent change and perform comparisons. The incidence rate of prostate cancer increased from 2007 to 2009 at an annual average of 39.3% (95% confidence interval (CI): -25.9, 161.8), 13.5% (95% CI: 11.7, 15.4), and 15.6% (95% CI: 11.9, 19.5), respectively, in Taean, nationwide, and in the coastal areas. The incidence of leukemia among women increased at an annual average of 9.5% (95% CI: -26.6, 63.4) in Taean and 0.6% (95% CI: 0.2, 0.9) nationwide; the rate decreased by 1.9% (95% CI: -12.8, 10.4) in the coastal areas. The trends between Taean County and the coastal areas differed only for prostate cancer ( p = 0.0004). The incidence of prostate cancer among Taean County residents has increased since the HSOS.

  17. Lung Cancer Mortality Trends in China from 1988 to 2013: New Challenges and Opportunities for the Government

    Directory of Open Access Journals (Sweden)

    Lijun Wang

    2016-10-01

    Full Text Available Background: As lung cancer has shown a continuously increasing trend in many countries, it is essential to stay abreast of lung cancer mortality information and take informed actions with a theoretical basis derived from appropriate and practical statistical methods. Methods: Age-specific rates were collected by gender and region (urban/rural and analysed with descriptive methods and age-period-cohort models to estimate the trends in lung cancer mortality in China from 1988 to 2013. Results: Descriptive analysis revealed that the age-specific mortality rates of lung cancer in rural residents increased markedly over the last three decades, and there was no obvious increase in urban residents. APC analysis showed that the lung cancer mortality rates significantly increased with age (20–84, rose slightly with the time period, and decreased with the cohort, except for the rural cohorts born during the early years (1909–1928. The trends in the patterns of the period and cohort effects showed marked disparities between the urban and rural residents. Conclusions: Lung cancer mortality remains serious and is likely to continue to rise in China. Some known measures are suggested to be decisive factors in mitigating lung cancer, such as environmental conservation, medical security, and tobacco control, which should be implemented more vigorously over the long term in China, especially in rural areas.

  18. THE FREQUENCY OF RISK FACTORS ON TRENDS OF PANCREATIC CANCER IN KOSOVO

    OpenAIRE

    Ramadani, Naser; Dedushi, Kreshnike; Mu?aj, Sefedin; Kabashi, Serbeze; Jerliu, Naim; Hoxhaj, Astrit

    2016-01-01

    The aim: The aim of this paper is to analyze different factors that influence the trends of pancreatic cancer mortality and morbidity of patients treated at the UCCK of Kosovo. Within this study, we have evaluated pancreatic cancer risk factors, durability and lethality regarding Kosovan patients who have been diagnosed and treated within Kosovo. The study in question is that of retrospective research traversing the period of 2011-2015. Materials and methodology: This retrospective research s...

  19. Male Breast Cancer as a Second Primary Cancer: Increased Risk Following Lymphoma.

    Science.gov (United States)

    Farr, Deborah E; Thomas, Alexandra; Khan, Seema Ahsan; Schroeder, Mary C

    2017-08-01

    Male breast cancer (MBC) as a second primary cancer (SPC) has a known association with prior MBC. However, its association with non-breast index malignancies, relative to population risk, has not been previously reported. Using Surveillance, Epidemiology, and End Results program (9 catchment area) data, we identified MBCs diagnosed from 1973-2012 as their SPC. Information regarding the index malignancy was also obtained. Standardized incidence ratios (SIR) of MBC as SPC were estimated, along with incidence rates and trends. Kaplan-Meier curves were used to estimate survival. Over a 38-year period, 464 MBCs were identified as SPC. The most common index malignancies were breast (SIR 30.86, 95% confidence interval [CI] 21.50-42.92, p  Male breast cancer as a SPC has increased markedly over 4 decades. Men with a history of lymphoma may experience higher-than-expected rates of breast SPC. These observations warrant further research, and suggest possible etiologic connections with disease biology, prior therapy, or genetics. This study reports that men are presenting more frequently to the clinic with breast cancer, both as an initial cancer and as a second cancer following an earlier malignancy. We also report the novel observation that men who survive lymphoma are at increased risk of developing a subsequent breast cancer. Further work is needed to better understand possible treatment or biologic causes of this association. More immediately, these findings suggest the need for heightened vigilance for male breast cancer overall and, in particular, for male lymphoma survivors. © AlphaMed Press 2017.

  20. Patterns of lung cancer mortality in 23 countries: Application of the Age-Period-Cohort model

    Directory of Open Access Journals (Sweden)

    Huang Yi-Chia

    2005-03-01

    Full Text Available Abstract Background Smoking habits do not seem to be the main explanation of the epidemiological characteristics of female lung cancer mortality in Asian countries. However, Asian countries are often excluded from studies of geographical differences in trends for lung cancer mortality. We thus examined lung cancer trends from 1971 to 1995 among men and women for 23 countries, including four in Asia. Methods International and national data were used to analyze lung cancer mortality from 1971 to 1995 in both sexes. Age-standardized mortality rates (ASMR were analyzed in five consecutive five-year periods and for each five-year age group in the age range 30 to 79. The age-period-cohort (APC model was used to estimate the period effect (adjusted for age and cohort effects for mortality from lung cancer. Results The sex ratio of the ASMR for lung cancer was lower in Asian countries, while the sex ratio of smoking prevalence was higher in Asian countries. The mean values of the sex ratio of the ASMR from lung cancer in Taiwan, Hong Kong, Singapore, and Japan for the five 5-year period were 2.10, 2.39, 3.07, and 3.55, respectively. These values not only remained quite constant over each five-year period, but were also lower than seen in the western countries. The period effect, for lung cancer mortality as derived for the 23 countries from the APC model, could be classified into seven patterns. Conclusion Period effects for both men and women in 23 countries, as derived using the APC model, could be classified into seven patterns. Four Asian countries have a relatively low sex ratio in lung cancer mortality and a relatively high sex ratio in smoking prevalence. Factors other than smoking might be important, especially for women in Asian countries.

  1. Brief Report: Anal Cancer in the HIV-Positive Population: Slowly Declining Incidence After a Decade of cART

    NARCIS (Netherlands)

    Richel, Olivier; van der Zee, Ramon P.; Smit, Colette; de Vries, Henry J. C.; Prins, Jan M.

    2015-01-01

    We surveyed trends in incidence (1995-2012) and risk factors for anal cancer in the Dutch HIV-positive population. After an initial increase with a peak incidence in 2005-2006 of 114 [95% confidence interval (CI): 74 to 169] in all HIV+ patients and 168 (95% CI: 103 to 259) in HIV+ men who have sex

  2. Time-Trend in Epidemiological and Pathological Features of Schistosoma-Associated Bladder Cancer

    International Nuclear Information System (INIS)

    ZAGHLOUL, M.S.; EL-BARADIE, M.; NAZMY, M.; NOUH, A.; MONEER, M.; YOUNIS, A.

    2008-01-01

    To investigate the different emerging trends in the features of bladder cancer along 17 years. Patients and Methods: During a 17-year period (1988- 2004), 5071 epithelial bladder cancer patients underwent radical cystectomy at the National Cancer Institute (NCI), Cairo University, Egypt. The time was divided into 3 time periods to detect changes of the clinico pathologic features of patients in these periods. Results: There was a significant progressive increase in the patients' age with time and decrease in squamous/ transitional ratio, with transient increase in male predominance during the 2nd time period. Moreover, there was a decrease in the well differentiated (grade 1) tumor (p<0.001) and an increase in the frequency of pelvic nodal involvement (p<0.001). Transitional cell carcinoma (TCC) patients were significantly older than those with squamous cell carcinoma (SCC) (p<0.001). Progressive increase of age with time was evident in TCC, SCC and adenocarcinoma patients. Male to female ratio changed significantly in TCC and SCC. Conclusion: Time trend was confirmed with relative decrease in frequency of SCC and increase of TCC with changes in their pathological details. The differences between their characteristics and that of the Western countries are decreasing.

  3. Cancer incidence rates and trends among children and adolescents in Piedmont, 1967-2011.

    Science.gov (United States)

    Isaevska, Elena; Manasievska, Milena; Alessi, Daniela; Mosso, Maria Luisa; Magnani, Corrado; Sacerdote, Carlotta; Pastore, Guido; Fagioli, Franca; Merletti, Franco; Maule, Milena

    2017-01-01

    In the past, increases in childhood cancer incidence were reported in Europe and North America. The aim of this study is to show updated patterns of temporal behavior using data of the Childhood Cancer Registry of Piedmont (CCRP), a region with approximately 4.5 million inhabitants in North-West Italy. CCRP has been recording incident cases in children (0-14 years) since 1967 and in adolescents (15-19) since 2000. Time trends were estimated as annual percent change (APC) over the 1976-2011 period for children, and over 2000-2011 for both children and adolescents. CCRP registered 5020 incident cases from 1967 to 2011. Incidence rates were 157 per million person-years for children (1967-2011) and 282 for adolescents (2000-2011). From 1976-2011, increasing trends were observed in children for all neoplasms (APC 1.1, 95%CI: 0.8; 1.5) and for both embryonal and non-embryonal tumors: 1.1%, (0.5; 1.6) and 1.2%, (0.7; 1.6), respectively. Increases were observed in several tumor types, including leukemia, lymphoma, central nervous system tumors and neuroblastoma. In 2000-2011, incidence rates showed mostly non statistically significant variations and large variability. The observation of trends over a long period shows that the incidence of most tumors has increased, and this is only partially explained by diagnostic changes. Large rate variability hampers interpretation of trend patterns in short periods. Given that no satisfying explanation for the increases observed in the past was ever found, efforts must be made to understand and interpret this peculiar and still ununderstood pattern of childhood cancer incidence.

  4. Cancer incidence rates and trends among children and adolescents in Piedmont, 1967-2011.

    Directory of Open Access Journals (Sweden)

    Elena Isaevska

    Full Text Available In the past, increases in childhood cancer incidence were reported in Europe and North America. The aim of this study is to show updated patterns of temporal behavior using data of the Childhood Cancer Registry of Piedmont (CCRP, a region with approximately 4.5 million inhabitants in North-West Italy. CCRP has been recording incident cases in children (0-14 years since 1967 and in adolescents (15-19 since 2000. Time trends were estimated as annual percent change (APC over the 1976-2011 period for children, and over 2000-2011 for both children and adolescents. CCRP registered 5020 incident cases from 1967 to 2011. Incidence rates were 157 per million person-years for children (1967-2011 and 282 for adolescents (2000-2011. From 1976-2011, increasing trends were observed in children for all neoplasms (APC 1.1, 95%CI: 0.8; 1.5 and for both embryonal and non-embryonal tumors: 1.1%, (0.5; 1.6 and 1.2%, (0.7; 1.6, respectively. Increases were observed in several tumor types, including leukemia, lymphoma, central nervous system tumors and neuroblastoma. In 2000-2011, incidence rates showed mostly non statistically significant variations and large variability. The observation of trends over a long period shows that the incidence of most tumors has increased, and this is only partially explained by diagnostic changes. Large rate variability hampers interpretation of trend patterns in short periods. Given that no satisfying explanation for the increases observed in the past was ever found, efforts must be made to understand and interpret this peculiar and still ununderstood pattern of childhood cancer incidence.

  5. Worldwide trend of atmospheric mercury since 1995

    Directory of Open Access Journals (Sweden)

    F. Slemr

    2011-05-01

    Full Text Available Concern about the adverse effects of mercury on human health and ecosystems has led to tightening emission controls since the mid 1980s. But the resulting mercury emissions reductions in many parts of the world are believed to be offset or even surpassed by the increasing emissions in rapidly industrializing countries. Consequently, concentrations of atmospheric mercury are expected to remain roughly constant. Here we show that the worldwide atmospheric mercury concentrations have decreased by about 20 to 38 % since 1996 as indicated by long-term monitoring at stations in the Southern and Northern Hemispheres combined with intermittent measurements of latitudinal distribution over the Atlantic Ocean. The total reduction of the atmospheric mercury burden of this magnitude within 14 years is unusually large among most atmospheric trace gases and is at odds with the current mercury emission inventories with nearly constant anthropogenic emissions over this period. This suggests a major shift in the biogeochemical cycle of mercury including oceans and soil reservoirs. Decreasing reemissions from the legacy of historical mercury emissions are the most likely explanation for this decline since the hypothesis of an accelerated oxidation rate of elemental mercury in the atmosphere is not supported by the observed trends of other trace gases. Acidification of oceans, climate change, excess nutrient input and pollution may also contribute by their impact on the biogeochemistry of ocean and soils. Consequently, models of the atmospheric mercury cycle have to include soil and ocean mercury pools and their dynamics to be able to make projections of future trends.

  6. Misperception of body weight among overweight Danish adults: trends from 1995 to 2008

    DEFF Research Database (Denmark)

    Matthiessen, Jeppe; Biltoft-Jensen, Anja Pia; Fagt, Sisse

    2013-01-01

    OBJECTIVE: To examine changes in the prevalence of overweight and weight misperception among overweight Danes from 1995 to 2008, and to identify factors associated with weight misperception. DESIGN: Cross-sectional studies, in which data on self-reported weight, height and self-perception...

  7. Scientific annual report 1973

    International Nuclear Information System (INIS)

    A report is given on the scientific research at DESY in 1973, which included the first storage of electrons in the double storage ring DORIS. Also mentioned are the two large spectrometers PLUTO and DASP, and experiments relating to elementary particles, synchrotron radiation, and the improvement of the equipment are described. (WL/AK) [de

  8. The increasing incidence of anal cancer: can it be explained by trends in risk groups?

    NARCIS (Netherlands)

    van der Zee, R. P.; Richel, O.; de Vries, H. J. C.; Prins, J. M.

    2013-01-01

    Anal cancer incidence is gradually increasing. The cause of this increase is not exactly known. This systematic literature review aimed to investigate the trend in time of anal cancer incidence and to find an explanation for the supposed increase. The TRIP database and PubMed were searched for

  9. Geographic Variations and Time Trends in Cancer Treatments in Taiwan.

    Science.gov (United States)

    Hsu, Jason C; Chang, Sheng-Mao; Lu, Christine Y

    2017-08-02

    Targeted therapies have become important treatment options for cancer care in many countries. This study aimed to examine recent trends in utilization of antineoplastic drugs, particularly the use of targeted therapies for treatment of cancer, by geographic region in Taiwan (northern, midwestern, southern, and eastern regions and the outer islands). This was a retrospective observational study of antineoplastic agents using 2009-2012 quarterly claims data from Taiwan's National Health Insurance Research Database. Yearly market shares by prescription volume and costs for targeted therapies among total antineoplastic agents by region were estimated. We used multivariate regression model and ANOVA to examine variations in utilization of targeted therapies between geographic regions and used ARIMA models to estimate longitudinal trends. Population-adjusted use and costs of antineoplastic drugs (including targeted therapies) were highest in the southern region of Taiwan and lowest in the outer islands. We found a 4-fold difference in use of antineoplastic drugs and a 49-fold difference in use of targeted therapies between regions if the outer islands were included. There were minimal differences in use of antineoplastic drugs between other regions with about a 2-fold difference in use of targeted therapies. Without considering the outer islands, the market share by prescription volume and costs of targeted therapies increased almost 2-fold (1.84-1.90) and 1.5-fold (1.26-1.61) respectively between 2009 and 2012. Furthermore, region was not significantly associated with use of antineoplastic agents or use of targeted therapies after adjusting for confounders. Region was associated with costs of antineoplastic agents but it was not associated with costs of targeted therapies after confounding adjustments. Use of antineoplastic drugs overall and use of targeted therapies for treatment of cancer varied somewhat between regions in Taiwan; use was notably low in the outer

  10. Trends in incidence, survival and mortality of childhood and adolescent cancer in Austria, 1994-2011.

    Science.gov (United States)

    Karim-Kos, Henrike E; Hackl, Monika; Mann, Georg; Urban, Christian; Woehrer, Adelheid; Slavc, Irene; Ladenstein, Ruth

    2016-06-01

    This is the first study on trends in cancer incidence, survival and mortality for children and adolescents in Austria. The aim was to assess to what extent progress against childhood and adolescent cancer has been made in Austria since the 1990s and to complement the childhood and adolescent cancer trends for Central Europe. All malignant neoplasms and non-malignant tumours of the Central Nervous System (CNS) in patients aged less than 20 years and diagnosed between 1994 and 2011 (N=5425) were derived from the Austrian National Cancer Registry (ANCR). Incidence and mortality trends were evaluated by the average annual percentage change (AAPC). Observed survival rates were calculated based on follow-up until December 31st 2013. Childhood cancer remained stable with 182 cases per million in 2011, but rose among girls by 1.4% (95% CI: .1, 3.6) annually due to an increase of non-malignant CNS tumours and Non-Hodgkin lymphoma. Adolescent cancer rose by 1.5% (95% CI: .4, 2.6) annually, from 182 cases per million in 1994-269 in 2011, especially leukaemia, CNS tumours (including non-malignant types) and epithelial tumours. Five-year survival improved by 5-7% reaching 86% for both groups (p<.05). Mortality declined by -2.4% (95% CI: -3.7, -1.2) and -2.0% (95% CI: -4.6, .5), respectively, especially for childhood leukaemia. Progress is demonstrated by improved survival and declined mortality most likely related to improved diagnostic techniques, more effective therapeutic regimes, supportive care and a central advisory function of experts in the Austrian paediatric oncology. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. [Trends in the prevalence of malaria and anemia at delivery in Libreville from 1995 to 2011].

    Science.gov (United States)

    Bouyou-Akotet, Marielle Karine; Nzenze-Afène, Solange; Mawili-Mboumba, Denise Patricia; Owono-Medang, Mathieu; Guiyedi, Vincent; Kombila, Maryvonne

    2011-01-01

    In 1995, 2005 and 2011, cross-sectional studies of 611 parturients at the Centre Hospitalier de Libreville in Gabon assessed the prevalence of maternal malaria and anaemia; two indicators of poor pregnancy outcomes. The prevalence of Plasmodium falciparum infection in maternal peripheral blood decreased from 25% in 2005 to 6% in 2011. Parasite density was significantly lower in 2005 (31 p/μL) than in 1995 (1,240 p/μL) or 2011 (35,055 p/μL). Anaemia prevalence was high (>50%) in 1995 and in 2005, but fell by more than 50% (24%) in 2011. After implementation of new malaria prevention strategies during pregnancy, the prevalence of both maternal peripheral P. falciparum infection and anaemia fell. Studies are necessary to assess the efficacy of these strategies and to seek other causes of anaemia.

  12. A Historical Review of "Contemporary Educational Psychology" from 1995 to 2010

    Science.gov (United States)

    Mitchell, Anita Witt; McConnell, John Robert, III

    2012-01-01

    The major themes and trends represented by the articles published in "Contemporary Educational Psychology" (CEP) from 1995 to 2010 are reviewed in this paper. Included are the major topics, theoretical perspectives, participant characteristics, research methods and statistics used, and highly cited papers. The most frequently occurring topic…

  13. Effect of the 1973 oil price embargo

    International Nuclear Information System (INIS)

    Goel, R.K.; Morey, M.J.

    1993-01-01

    This paper focuses on the effect of the oil shock of 1973 on US gasoline demand by examining the price elasticities of demand before and after the 1973 embargo. Price elasticities provide useful input to the development of public policy dealing with taxation and pollution control. The extensive data used include state level observations for nearly three decades spanning 1952-80. We apply non-parametric regression methods that are more appropriate to our investigation than traditional parametric techniques. Unlike standard regression techniques, non-parametric methods neither assume a functional form for the demand relation nor restrict the distribution of the dependent variable. Our results show that the mean price elasticity of gasoline demand for the USA was - 0.243 for 1952-73 and the corresponding number for 1973-80 was - 0.576, statistically different at the 5% level of significance. The relatively higher price elasticity in the post-embargo period is consistent with the hypothesis that consumers sought substitutes and restricted their consumption in response to prices as well as social responsibility. The policy implications of these results are also discussed. (author)

  14. Incidence trends and mortality rates of gastric cancer in Israel.

    Science.gov (United States)

    Lavy, Ron; Kapiev, Andronik; Poluksht, Natan; Halevy, Ariel; Keinan-Boker, Lital

    2013-04-01

    Gastric cancer is the fourth most common malignancy worldwide. The incidence trends and mortality rates of gastric cancer in Israel have not been studied in depth. The aim of our study was to try and investigate the aforementioned issues in Israel in different ethnic groups. This retrospective study is based on the data of The Israel National Cancer Registry and The Central Bureau of Statistics. Published data from these two institutes were collected, summarized, and analyzed in this study. Around 650 new cases of gastric cancer are diagnosed yearly in Israel. While we noticed a decline during the period 1990-2007 in the incidence in the Jewish population (13.6-8.9 and 6.75-5.42 cases per 100,000 in Jewish men and women, respectively), an increase in the Arab population was noticed (7.7-10.2 and 3.7-4.2 cases per 100,000 in men and women, respectively). Age-adjusted mortality rates per 10,000 cases of gastric cancer decreased significantly, from 7.21 in 1990 to 5.46 in 2007, in the total population. The 5-year relative survival showed a slight increase for both men and women. There is a difference in the incidence and outcome of gastric cancer between the Jewish and Arab populations in Israel. The grim prognosis of gastric cancer patients in Israel is probably due to the advanced stage at which gastric cancer is diagnosed in Israel.

  15. IAEA Newsbriefs. V. 10, no. 3(69). Nov-Dec 1995

    International Nuclear Information System (INIS)

    1995-01-01

    This issue gives brief information on the following topics: IAEA Director General Addresses United Nations, IAEA Board of Governors' December Meetings, UN General Assembly Commends Work of IAEA, Oceanographic Investigations of Radioactive Pollution, Cancer Radiotherapy Using Heavy Charged Particles, Highlights of the 1995 IAEA General Conference, Director General's Statement to 1995 IAEA General Conference, General Conference Scientific Programme, Countries Invited to More Widely Apply INES Scale, Safety Meeting on Kozloduy in Bulgaria, Selection of Dry Storage Technologies for Spent Fuel, India Presents Sculpture to the IAEA, IAEA Seminars and Symposia, and other short information

  16. Characteristic Trend Analysis of Cancer Patients Hospitalized in Shanxi Tumor Hospital for the First Time during 2001 and 2010.

    Science.gov (United States)

    Zhang, Wen-Li; Wang, Yan; Han, Cun-Zhi

    2015-01-01

    To observe and analyze the characteristic trend of cancer patients hospitalized for the first time in Shanxi Tumor Hospital from 2001 to 2010, clinical data including case number, age, gender, and frequency of different tumor occurrences were collected and statistically analyzed. (i) From 2001 to 2010, the number of cancer patients hospitalized for the first time increased by 1.3-fold; (ii) The patient overall average age also increased from 51.8 to 54.4, for males from 55.5 to 58.7 and females from 48.4 to 51.1, respectively. (iii) Male patients accounted for 43-48% and females accounted for 52-57% of the total. The percentage of female patients was higher than that of male patients in every year and showed an upward trend over the years, while that of the males showed a downward trend (χ2 =7.031, p=0.008); (iv) Among the top 6 most common cancers, lung, cervical, esophageal, colorectal and breast cancers tended to increase over the years (ppatients hospitalized for the first time during the past 10 years increased year by year, and was higher for female than male; (ii) the average age of patients increased year after year and was greater for male than female; (iii) the number of patients with lung cancer, cervical cancer, esophageal cancer, colorectal cancer and breast cancer increased over years.

  17. Effects of socioeconomic factors on secular trends in suicide in Japan, 1953-86.

    Science.gov (United States)

    Motohashi, Y

    1991-04-01

    The effects of socioeconomic factors on secular trends in suicide rates in Japan for the periods 1953-72 and 1973-86 were investigated using twelve socioeconomic indicators. Multiple regression analysis showed that the socioeconomic indicators affecting suicide rates were not identical in the two periods. The rates in both sexes in 1953-72 were closely related to unemployment rate and the labour force but between 1973 and 1986, divorce rate and the proportion in tertiary industry were most influential. The changes reflect the socioeconomic changes in industrial structure in Japan in transition from an industrial to a service economy.

  18. Childhood Leukaemia Incidence in Hungary, 1973-2002. Interpolation Model for Analysing the Possible Effects of the Chernobyl Accident

    International Nuclear Information System (INIS)

    Toeroek, Szabolcs; Borgulya, Gabor; Lobmayer, Peter; Jakab, Zsuzsanna; Schuler, Dezsoe; Fekete, Gyoergy

    2005-01-01

    The incidence of childhood leukaemia in Hungary has yet to be reported, although data are available since the early 70s. The Hungarian data therefore cover the time before and after the Chernobyl nuclear accident (1986). The aim of this study was to assess the effects of the Chernobyl accident on childhood leukaemia incidence in Hungary. A population-based study was carried out using data of the National Paediatric Cancer Registry of Hungary from 1973 to 2002. The total number of cases was 2204. To test the effect of the Chernobyl accident the authors applied a new approach called 'Hypothesized Impact Period Interpolation'-model, which takes into account the increasing trend of childhood leukaemia incidence and the hypothesized exposure and latency times. The incidence of leukaemia in the age group 0-14 varied between 33.2 and 39.4 per million person-years along the observed 30 year period, and the incidence of childhood leukaemia showed a moderate increase of 0.71% annually (p=0.0105). In the period of the hypothesized impact of the Chernobyl accident the incidence rate was elevated by 2.5% (95% CI: -8.1%; +14.3%), but this change was not statistically significant (p=0.663). The age standardised incidence, the age distribution, the gender ratio, and the magnitude of increasing trend of childhood leukaemia incidence in Hungary were similar to other European countries. Applying the presented interpolation method the authors did not find a statistically significant increase in the leukaemia incidence in the period of the hypothesized impact of the Chernobyl accident

  19. Trends in kidney cancer among the elderly in Denmark, 1980-2012

    DEFF Research Database (Denmark)

    Azawi, Nessn H; Joergensen, Simon Moeller; Jensen, Niels Viggo

    2016-01-01

    Background The purpose of this study is to elucidate incidence, mortality, survival, and prevalence of kidney cancer in elderly persons compared with younger persons in Denmark. Material and methods Cancer of the kidney was defined as ICD-10 code DC 64. Data derived from the NORDCAN database...... of patients diagnosed with kidney cancer over the age of 70 years has decreased from 43% in 1980 to 32% in 2012 in men and remained almost constant in women, around 50%. Incidence rates were at least five times higher in men aged 70 years more but there was no particular trend with time. In men aged less than......-year relative survival increased steadily over time for all age groups but the survival was lower for patients aged 70 years or more than for younger patients. The prevalence increased three times from 1559 patients being alive after kidney cancer in1980 to 4713 in 2012. Conclusion A challenge in managing...

  20. Trends in cardiovascular disease biomarkers and their socioeconomic patterning among adults in the Scottish population 1995 to 2009: cross-sectional surveys

    Science.gov (United States)

    Davies, Carolyn Anne; Gray, Linsay; Bromley, Catherine; Capewell, Simon; Leyland, Alastair

    2012-01-01

    Objectives To examine secular and socioeconomic changes in biological cardiovascular disease risk factor and biomarker prevalences in the Scottish population. This could contribute to an understanding of why the decline in coronary heart disease mortality in Scotland has recently stalled along with persistence of associated socioeconomic inequalities. Design Cross-sectional surveys. Setting Scotland. Participants Scottish Health Surveys: 1995, 1998, 2003, 2008 and 2009 (6190, 6656, 5497, 4202 and 4964 respondents, respectively, aged 25–64 years). Primary outcome measures Gender-stratified, age-standardised prevalences of obesity, hypertension, hypercholesterolaemia and low high-density lipoprotein cholesterol blood concentration as well as elevated fibrinogen and C reactive protein concentrations according to education and social class groupings. Inequalities were assessed using the slope index of inequality, and time trends were assessed using linear regression. Results The prevalence of obesity, including central obesity, increased between 1995 and 2009 among men and women, irrespective of socioeconomic position. In 2009, the prevalence of obesity (defined by body mass index) was 29.8% (95% CI 27.9% to 31.7%) for men and 28.2% (26.3% to 30.2%) for women. The proportion of individuals with hypertension remained relatively unchanged between 1995 and 2008/2009, while the prevalence of hypercholesterolaemia declined in men from 79.6% (78.1% to 81.1%) to 63.8% (59.9% to 67.8%) and in women from 74.1% (72.6% to 75.7%) to 66.3% (62.6% to 70.0%). Socioeconomic inequalities persisted over time among men and women for most of the biomarkers and were particularly striking for the anthropometric measures when stratified by education. Conclusions If there are to be further declines in coronary heart disease mortality and reduction in associated inequalities, then there needs to be a favourable step change in the prevalence of cardiovascular disease risk factors. This may

  1. Use of primary care data for detecting impetigo trends, United kingdom, 1995-2010.

    Science.gov (United States)

    Shallcross, Laura J; Petersen, Irene; Rosenthal, Joe; Johnson, Anne M; Freemantle, Nick; Hayward, Andrew C

    2013-10-01

    Using a primary care database, we identified a major increase in impetigo in the United Kingdom during 1995-2010. Despite a doubled rate of primary care consultations, this increase was not identified by routine surveillance. Primary care databases are a valuable and underused source of surveillance data on infectious diseases.

  2. [Trends in the mortality of liver cancer in Qidong, China: an analysis of fifty years].

    Science.gov (United States)

    Chen, Jian-guo; Zhu, Jian; Zhang, Yong-hui; Chen, Yong-sheng; Ding, Lu-lu; Lu, Jian-hua; Zhu, Yuan-rong

    2012-07-01

    To describe and analyze the charecteristics and trends of liver cancer mortality during the past fifty years in Qidong, China. Retrospective mortality survey was conducted to get the data on liver cancer death in the period of 1958-1971, and the data from 1972 to 2007 were obtained from the records of cancer registration in Qidong. The crude mortality rate (CR) of liver cancer, and age-standardized rate by Chinese population (CASR) and by world population (WASR) were calculated and analyzed. The total percent changes (PC) and annual percent changes (APC) were used for evaluating the increasing trends of the mortality. The sex-specific rate, age-specific rate, truncated rate of the age group 35 - 64, cumulative rate of the age group 0-74, cumulative risk, period-rate, and the rate for age-birth cohort were compared. The natural death rate in Qidong residents for the past five-decade period experienced a wave interval of 8.62‰ in 1958 down to 5.37‰ in 1979, and up to 7.75‰ in 2007. The mortality rate for all-site cancers was increased from 56.69 per 100, 000 to 234.97 per 100, 000. The mortality rate of liver cancer, being 20.45 per 100, 100 in 1958 was increased to 49.04 per 100, 000 in 1972, and up to 69.29 per 100, 000 in 2007. According to the registration data of 1972 - 2007, the death from liver cancer was accounted for 34.88% of all deaths due to cancers, with a CR of 58.86 per 100, 000, CASR of 38.36 per 100, 000, and WASR, 49.37 Per 100, 000 in Qidong. The truncated rate for the age group 35 - 64 was 117.08 per 100, 000, and the cumulative rate for the age group 0-74 and the cumulative risk were 5.15% and 5.02%, respectively. The CRs for males was 90.52 per 100, 000 and for females was 27.93 per 100, 000, with a sex ratio of 3.24:1. For the period of 1972 - 2007, the PC for CR was 49.71%, and APC was +1.41%, showing an increasing variation tendency. The APCs for CASR and WASR, however, were decreasing, with a percentage of -1.11%, and -0

  3. Results of environmental radioactivity measurements in the Member States of European Community for air-deposition-water 1973-1974, milk 1972-1973-1974

    International Nuclear Information System (INIS)

    1977-01-01

    The present document is the fifteenth report published by the Health and Safety Directorate of the Commission of the European Communities concerning ambient radioactivity and using the data collected by the stations in charge of the surveillance of the environmental radioactivity in Member States. The results are compiled and extracted from the data sent to the Commission in application of Article 36 of the Treaty of Rome instituting the European Atomic Energy Community. It is the first document in which data from Denmark, Ireland and the United Kingdom which joined the European Community on 1 January 1973 are included in addition to data from Belgium, the Federal Republic of Germany, France, Italy, Luxembourg and the Netherlands. The results presented in this report cover the years 1973 and 1974 for air deposition and surface water and the years 1972, 1973 and 1974 for milk

  4. Cancers of the Brain and CNS: Global Patterns and Trends in Incidence.

    Science.gov (United States)

    Mortazavi, S M J; Mortazavi, S A R; Paknahad, M

    2018-03-01

    Miranda-Filho et al. in their recently published paper entitled "Cancers of the brain and CNS: global patterns and trends in incidence" provided a global status report of the geographic and temporal variations in the incidence of brain and CNS cancers in different countries across continents worldwide. While the authors confirm the role of genetic risk factors and ionizing radiation exposures, they claimed that no firm conclusion could be drawn about the role of exposure to non-ionizing radiation. The paper authored by Miranda-Filho et al. not only addresses a challenging issue, it can be considered as a good contribution in the field of brain and CNS cancers. However, our correspondence addresses a basic shortcoming of this paper about the role of electromagnetic fields and cancers and provides evidence showing that exposure to radiofrequency electromagnetic fields (RF-EMFs), at least at high levels and long durations, can increases the risk of cancer.

  5. Smoking among adolescents in Muenster, Germany: increase in prevalence (1995-2000) and relation to tobacco advertising.

    Science.gov (United States)

    Maziak, Wasim; Rzehak, Peter; Keil, Ulrich; Weiland, Stephan K

    2003-02-01

    Understanding patterns and trends of smoking among youths is of major importance for the assessment of the burden of smoking in the society and efforts to decrease it. The aims were to determine the prevalence and trends of smoking among adolescents in Muenster, Germany, and to assess its relation to youths' awareness of tobacco advertisement. Information on smoking habits was collected during two school-based surveys (1994/1995 and 1999/2000) of 12- to 15-year-old adolescents (3934 students in 1994/5 and 4028 students in 1999/2000) in Muenster, Germany. In addition, in 1994/1995 information about youths' awareness and appreciation of tobacco advertisement was collected. During the 5-year period, the prevalence of current smoking increased from 21.3 to 28.3%, and daily smoking increased from 10.0 to 14.2%. Among girls, daily smoking increased by 62% during this period. Almost all participants (94%) in 1994/1995 knew a tobacco brand, and appreciation of tobacco advertisement was strongly associated with the frequency of smoking. Smoking is increasing among adolescents in Germany especially among girls. These data are a cause of concern and call for efforts to reverse these trends, which should include a ban on tobacco advertisement in Germany.

  6. Spills Action Centre summary report of 1995 spills

    International Nuclear Information System (INIS)

    1996-12-01

    A summary of spills reported to the Ontario Ministry of Environment and Energy during 1995 was presented. The Ministry's Spill Action Centre is on call 24-hours per day to receive and respond to reports of spills and other urgent environmental incidents. Some 5,000 spills were documented in 1995. Oils and fuels accounted for 59 per cent of the spilled materials, chemicals and chemical solutions for 17 per cent, wastes and waste waters for 16 per cent, and gaseous materials for 5 per cent. Unknown materials accounted for 3 per cent. Most of the spills involved small volumes. Equipment failure and operator error were the major reasons for spills. All occurrences reported are stored on a computerized database. The information is used to develop new pollution abatement programs and spill prevention initiatives as trends are identified. 14 tabs., 14 figs

  7. Report on the operation in 1973 of the FR 2 research reactor

    International Nuclear Information System (INIS)

    Moeller, I.; Steiger, W.

    1975-04-01

    Also in 1973, the heavy-water moderated research and testing reactor FR 2 was operated to schedule at 44 MW nominal power. Again, the availability of the plant was slightly improved. Experimental utilization through instrumented irradiation capsules strongly increased as compared to the previous year. Up to 16 capsule test rigs at a time were inserted in the reactor. As to the beam tube experiments, up to 13 experiments covering a total of 18 test rigs were conducted simultaneously at the 12 reasonably usable beam holes. At the beginning of the year all of the positions available were occupied by 5 loop experiments. Isotope production reached its highest value with a total of 2,372 irradiated capsules (1.3% more than the year before). Some remarkable figures characterized the year 1973: On August 16, 1973 ten years of full power operation at a nominal power of 12 and 44 MW, respectively, had been reached. On July 24, 1973 the 50,000th isotope irradiation was performed in the reactor and on December 26, 1973 a total energy release of 100,000 MWd was recorded. Moreover, the 125,000th visitor of the reactor was welcomed on December 6, 1973. (orig./UA) [de

  8. Latest discoveries and trends in translational cancer research: highlights of the 2008 Annual Meeting of the American Association for Cancer Research.

    Science.gov (United States)

    Cho, William C S

    2008-08-01

    The Annual Meeting of the American Association for Cancer Research (AACR) is the world's largest and most comprehensive gathering of cancer researchers. At the 2008 AACR Annual Meeting, innovative research approaches, novel technologies, potentially life-saving therapies in the pipeline, late-breaking clinical trial findings, and new approaches to cancer prevention were presented by top scientists. Reflecting the global state of cancer research with an eye toward future trends, several areas of great science and discovery in the cancer field were shared in this report, which include cancer biomarkers, the role of microRNAs in cancer research, cancer stem cells, tumor microenvironment, targeted therapy, and cancer prevention. This article presents an overview of hot topics discussed at the 2008 AACR Annual Meeting and recapitulates some scientific sessions geared toward new technologies, recent progress, and current challenges reported by cancer researchers. For those who did not attend the meeting, this report may serve as a highlight of this important international cancer research meeting.

  9. What Buys Happiness? Analyzing Trends in Subjective Well-Being in 15 European Countries, 1973-2002

    DEFF Research Database (Denmark)

    Bjørnskov, Christian; Gupta, Nabanita Datta

    Trends in life satisfaction are examined across 15 European countries employing a modified version of Kendall's Tau. Analyses show that GDP growth relative to growth in the preceding period is a determinant of the trends; the same holds for the growth in life expectancy while the contemporaneous ...... growth in the current account balance exerts a positive influence. Relative unemployment growth becomes significant when interacted with a measure of political ideology. The effects of relative GDP growth vary with median ideology.......Trends in life satisfaction are examined across 15 European countries employing a modified version of Kendall's Tau. Analyses show that GDP growth relative to growth in the preceding period is a determinant of the trends; the same holds for the growth in life expectancy while the contemporaneous...

  10. Compilation of opinion expressed by CCTN in 1995; Raccolta dei pareri espressi dalla Commissione Consultiva Tossicologica Nazionale nel 1995

    Energy Technology Data Exchange (ETDEWEB)

    Mucci, Nicolina [ISPESL, Dip. di Medicina del Lavoro, Monteporzio Catone, Rome (Italy); Camoni, Ivano [Istituto Superiore di Sanita` , Lab. di Tossicologia Applicata, Rome (Italy)

    1996-11-01

    The opinions expressed by the National Advisory Toxicological Committee (CCTN) of Italy in 1995 are presented. Among the most important opinions the following may be mentioned: (1) adaption of the allocations of carcinogenicity, mutagenicity and reproductive-toxicity to the criteria elaborated by the CCTN in 1994; (2) lung cancer risk estimation associated with exposure to polyciclic aromatic hydrocarbons from motor-vehicle exhaust emission; (3) cancerogenicity of the antiblastic drugs.

  11. Screening frequency and atypical cells and the prediction of cervical cancer risk.

    Science.gov (United States)

    Chen, Yun-Yuan; You, San-Lin; Koong, Shin-Lan; Liu, Jessica; Chen, Chi-An; Chen, Chien-Jen

    2014-05-01

    To evaluate the screening efficacy and importance of atypical squamous cells and atypical glandular cells in predicting subsequent cervical cancer risk. This national cohort study in Taiwan analyzed associations between Pap test screening frequency and findings in 1995-2000 and subsequent risk of squamous cell carcinoma and adenocarcinoma after 2002. Women aged 30 years or older in 1995 without a cervical cancer history were included. Multivariate-adjusted hazard ratios and their 95% confidence intervals (CIs) were assessed using Cox regression analysis. During a total follow-up of 31,693,980 person-years in 2002-2008, 9,471 squamous cell carcinoma and 1,455 adenocarcinoma cases were newly diagnosed, resulting in 2,067 deaths. The risk of developing and dying from squamous cell carcinoma decreased significantly with increasing attendance frequency between 1995 and 2000 (all P values for trend1995-2000 had 0.69-fold and 0.35-fold decrease in incidence and mortality of adenocarcinoma, respectively, compared with women who never attended any screenings. Abnormal cytologic findings were significant predictors of the incidence and mortality of cervical cancers. The adjusted hazard ratio (95% CI) of developing squamous cell carcinoma was 29.94 (22.83-39.25) for atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesions, and the adjusted hazard ratio (95% CI) of developing adenocarcinoma was 49.43 (36.49-66.97) for atypical glandular cells. Significant reductions in cervical adenocarcinoma occurred in women who attend three or more annual screenings in 6 years. High-grade atypical squamous cells and atypical glandular cells are important predictors of subsequent adenocarcinoma and squamous cell carcinoma. II.

  12. Trends in social security benefits for oral and oropharyngeal cancer from 2006 to 2013 in Brazil.

    Science.gov (United States)

    Bomfim, Rafael Aiello; Cascaes, Andreia Morales

    2018-01-01

    to analyze the trends in the concession of social security sick pay for oral and oropharyngeal cancer, from 2006 to 2013, in Brazil. time series study using data of workers insured by the Brazilian National Institute of Social Security (INSS); Prais-Winsten generalized linear regressions were used to calculate the annual percentage change (APC). social security benefits for oral and oropharyngeal cancer presented significant increase (APC=9.0%; 95%CI 1.4; 17.4); benefits for other parts of the mouth, nasopharynx, oropharynx, floor of mouth and palate have also shown significant increase; the areas of trade (5.5%) and manufacturing (5.2%) were the most prevalent activities; there was a high proportion of fields in blank in the information systems (average of 72.9%). trends in occupational benefits for oral and oropharyngeal cancer showed significant increase.

  13. Incidence, Trends and Ethnic Differences of Oropharyngeal, Anal and Cervical Cancers: Singapore, 1968-2012.

    Directory of Open Access Journals (Sweden)

    Jennifer O Lam

    Full Text Available In recent decades, several Western countries have reported an increase in oropharyngeal and anal cancers caused by human papillomavirus (HPV. Trends in HPV-associated cancers in Asia have not been as well described. We describe the epidemiology of potentially HPV-related cancers reported to the Singapore Cancer Registry from 1968-2012. Analysis included 998 oropharyngeal squamous cell carcinoma (OPSCC, 183 anal squamous cell carcinoma (ASCC and 8,019 invasive cervical cancer (ICC cases. Additionally, 368 anal non-squamous cell carcinoma (ANSCC and 2,018 non-oropharyngeal head and neck carcinoma (non-OP HNC cases were included as comparators. Age-standardized incidence rates (ASR were determined by gender and ethnicity (Chinese, Malay and Indian. Joinpoint regression was used to evaluate annual percentage change (APC in incidence. OPSCC incidence increased in both genders (men 1993-2012, APC = 1.9%, p<0.001; women 1968-2012, APC = 2.0%, p = 0.01 and was 5 times higher in men than women. In contrast, non-OP HNC incidence declined between 1968-2012 among men (APC = -1.6%, p<0.001 and women (APC = -0.4%, p = 0.06. ASCC and ANSCC were rare (ASR = 0.2 and 0.7 per 100,000 person-years, respectively and did not change significantly over time except for increasing ANSCCs in men (APC = 2.8%, p<0.001. ICC was the most common HPV-associated cancer (ASR = 19.9 per 100,000 person-years but declined significantly between 1968-2012 (APC = -2.4%. Incidence of each cancer varied across ethnicities. Similar to trends in Western countries, OPSCC incidence increased in recent years, while non-OP HNC decreased. ICC remains the most common HPV-related cancer in Singapore, but Pap screening programs have led to consistently decreasing incidence.

  14. Vital Signs: Trends in Incidence of Cancers Associated with Overweight and Obesity - United States, 2005-2014.

    Science.gov (United States)

    Steele, C Brooke; Thomas, Cheryll C; Henley, S Jane; Massetti, Greta M; Galuska, Deborah A; Agurs-Collins, Tanya; Puckett, Mary; Richardson, Lisa C

    2017-10-03

    Overweight and obesity are associated with increased risk of at least 13 different types of cancer. Data from the United States Cancer Statistics for 2014 were used to assess incidence rates, and data from 2005 to 2014 were used to assess trends for cancers associated with overweight and obesity (adenocarcinoma of the esophagus; cancers of the breast [in postmenopausal women], colon and rectum, endometrium, gallbladder, gastric cardia, kidney, liver, ovary, pancreas, and thyroid; meningioma; and multiple myeloma) by sex, age, race/ethnicity, state, geographic region, and cancer site. Because screening for colorectal cancer can reduce colorectal cancer incidence through detection of precancerous polyps before they become cancerous, trends with and without colorectal cancer were analyzed. In 2014, approximately 631,000 persons in the United States received a diagnosis of a cancer associated with overweight and obesity, representing 40% of all cancers diagnosed. Overweight- and obesity-related cancer incidence rates were higher among older persons (ages ≥50 years) than younger persons; higher among females than males; and higher among non-Hispanic black and non-Hispanic white adults compared with other groups. Incidence rates for overweight- and obesity-related cancers during 2005-2014 varied by age, cancer site, and state. Excluding colorectal cancer, incidence rates increased significantly among persons aged 20-74 years; decreased among those aged ≥75 years; increased in 32 states; and were stable in 16 states and the District of Columbia. The burden of overweight- and obesity-related cancer is high in the United States. Incidence rates of overweight- and obesity-related cancers except colorectal cancer have increased in some age groups and states. The burden of overweight- and obesity-related cancers might be reduced through efforts to prevent and control overweight and obesity. Comprehensive cancer control strategies, including use of evidence

  15. [Trend pattern of the incidence of thyroid cancer in Murcia Region (Spain) from 1984 to 2008].

    Science.gov (United States)

    Chirlaque, María Dolores; Moldenhauer, Fernando; Salmerón, Diego; Navarro, Carmen

    2014-01-01

    To study the trend pattern of the incidence of thyroid cancer. We selected incident cases of thyroid cancer occurring in the Region of Murcia (Spain) in 1984-2008. The variables gathered were age, sex, date of diagnosis, and morphology. We calculated incidence rates and the annual percentage of change using Bayesian age-period-cohort models. During the study period, 1414 cases were diagnosed, representing an increase in adjusted rates from 2.9/100000 in 1984-1988 to 7.3 in 2004-2008. The incidence was 3.5 times higher in women than in men and the most frequent morphology was papillary carcinoma (67.7%). An increasing trend was found in both genders; these increments were more pronounced in papillary carcinoma. In women, the incidence increased with age, calendar year, and in those born in 1945-1963. The incidence of papillary microcarcinoma increased four-fold in women. Thyroid cancer used to be a rare cancer but has become an emerging tumor. The greatest changes were found in papillary thyroid cancer, including a gradual increase in the proportion of microcarcinoma. Copyright © 2014 SESPAS. Published by Elsevier Espana. All rights reserved.

  16. Trend and forecasting rate of cancer deaths at a public university hospital using univariate modeling

    Science.gov (United States)

    Ismail, A.; Hassan, Noor I.

    2013-09-01

    Cancer is one of the principal causes of death in Malaysia. This study was performed to determine the pattern of rate of cancer deaths at a public hospital in Malaysia over an 11 year period from year 2001 to 2011, to determine the best fitted model of forecasting the rate of cancer deaths using Univariate Modeling and to forecast the rates for the next two years (2012 to 2013). The medical records of the death of patients with cancer admitted at this Hospital over 11 year's period were reviewed, with a total of 663 cases. The cancers were classified according to 10th Revision International Classification of Diseases (ICD-10). Data collected include socio-demographic background of patients such as registration number, age, gender, ethnicity, ward and diagnosis. Data entry and analysis was accomplished using SPSS 19.0 and Minitab 16.0. The five Univariate Models used were Naïve with Trend Model, Average Percent Change Model (ACPM), Single Exponential Smoothing, Double Exponential Smoothing and Holt's Method. The overall 11 years rate of cancer deaths showed that at this hospital, Malay patients have the highest percentage (88.10%) compared to other ethnic groups with males (51.30%) higher than females. Lung and breast cancer have the most number of cancer deaths among gender. About 29.60% of the patients who died due to cancer were aged 61 years old and above. The best Univariate Model used for forecasting the rate of cancer deaths is Single Exponential Smoothing Technique with alpha of 0.10. The forecast for the rate of cancer deaths shows a horizontally or flat value. The forecasted mortality trend remains at 6.84% from January 2012 to December 2013. All the government and private sectors and non-governmental organizations need to highlight issues on cancer especially lung and breast cancers to the public through campaigns using mass media, media electronics, posters and pamphlets in the attempt to decrease the rate of cancer deaths in Malaysia.

  17. Use of a case-mix approach to study the trends in the incidence of second primary cancers.

    Science.gov (United States)

    Gass, Boris; Marrer, Emilie; Bara, Simona; Ligier, Karine; Molinié, Florence; Colonna, Marc; Daubisse-Marliac, Laetitia; Trétarre, Brigitte; Lapôtre-Ledoux, Bénédicte; Woronoff, Anne-Sophie; Guizard, Anne-Valérie; Bouvier, Véronique; Troussard, Xavier; Gaiddon, Christian; Klein, Delphine; Velten, Michel; Jégu, Jérémie

    2018-05-01

    To analyze trends in second primary cancer (SPC) incidence by using a case-mix approach to standardize on first cancer site distribution. Cases registered by 13 French cancer registries between 1989 and 2010 and followed-up until June 2013 were included. The person-year approach was used to compute standardized incidence ratios (SIRs) of metachronous SPC. Usual SIRs and cancer site-specific weighted SIRs called "case-mix SIRs" (cmSIRs) were estimated by sex and calendar period of first cancer diagnosis. Calendar trends in SIRs and cmSIRs were compared. More than 2.9 million person-years at risk were included. Among males, SIRs dropped from 1.49 to 1.23 between 1989-1994 and 2005-2010, while cmSIRs decreased from 1.40 to 1.27. This difference seems mainly related to a stronger representation of prostate cancers (at lower risk of SPC) and a weaker contribution of bladder and head and neck cancers (at higher risk of SPC) in recent periods of diagnosis. Among females, both SIRs and cmSIRs have remained stable at around 1.22 and 1.21, respectively. The cmSIR is an indicator that is not influenced by changes in first cancer site distribution. Its use should be encouraged to assess second cancer incidence control. Copyright © 2018 Elsevier Inc. All rights reserved.

  18. 1973 Ispra - J.R.C. - Annual Report

    International Nuclear Information System (INIS)

    Angelini, A.

    1974-12-01

    This report is a comprehensive review of the work carried out during 1973 in the Ispra establishment of the Joint Research Centre. The first part is devoted to a description of the activity carried out in the frame of the so-called objectives of the 1973 research programme. In the second part are described, from the viewpoint of the Scientific Divisions of the Centre, some of the most relevant scientific and technical achievements. In the third part the operation of the big installations is reported. The fourth part treats both the technical and adminictrative support activities. A bibliography of reports, contributions to conferences, seminars and meetings etc. is given at the end

  19. Profile of Undergraduate Students: Trends from Selected Years, 1995-96 to 2007-08. Web Tables. NCES 2010-220

    Science.gov (United States)

    Staklis, Sandra; Chen, Xianglei

    2010-01-01

    From 1995-96 to 2007-08, the number of students enrolled in undergraduate education in the United States grew from about 16.7 million to 21 million. These Web Tables provide information on undergraduates during the 1995-96, 1999-2000, 2003-04, and 2007-08 academic years. Estimates are presented for all undergraduates and for undergraduates who…

  20. The carbon footprint of Greek households (1995–2012)

    International Nuclear Information System (INIS)

    Markaki, M.; Belegri-Roboli, A.; Sarafidis, U.; Mirasgedis, S.

    2017-01-01

    The goal of this paper is twofold: i) to investigate the carbon footprint of Greek households throughout the period 1995–2012, in order to identify the main socio-economic factors that affect GHG emissions, and ii) to evaluate the effectiveness of the implemented policies to tackle climate change. In this, a consumption-based emissions inventory approach is applied. The analysis is based on an environmentally-extended input-output model including direct CO_2 emissions from households, indirect CO_2 emissions from electricity consumption and indirect CO_2 emissions from energy used in the production of goods and services purchased by households, domestic or imported. Statistical analysis and appropriate regression models were developed in order to identify the main factors influencing the carbon footprint of Greek households. The results indicate that the observed trends during the period 1995–2008 can be attributed to the effect of high economic growth. This trend is partially counterbalanced by favorable weather conditions and the implementation of greenhouse mitigation policies and measures mainly in the supply side. Since 2008 the shrinking household income is the dominant driver. In addition, the effectiveness of energy conservation policies and measures in place is rather low, while the effect of imports is limited. - Highlights: • The factors influencing the carbon footprint of Greek households have been analyzed. • The analysis is based on consumption-based GHG inventories. • High economic growth resulted in carbon footprint increases during 1995–2008. • Carbon footprint reduction after 2008 is attributed to shrinking of household income. • Mitigation measures in power and manufacturing sectors reduced carbon footprint.

  1. Dietary nitrate and nitrite and the risk of thyroid cancer in the NIH-AARP Diet and Health Study.

    Science.gov (United States)

    Kilfoy, Briseis A; Zhang, Yawei; Park, Yikyung; Holford, Theodore R; Schatzkin, Arthur; Hollenbeck, Albert; Ward, Mary H

    2011-07-01

    During the past several decades, an increasing incidence of thyroid cancer has been observed worldwide. Nitrate inhibits iodide uptake by the thyroid, potentially disrupting thyroid function. An increased risk of thyroid cancer associated with nitrate intake was recently reported in a cohort study of older women in Iowa. We evaluated dietary nitrate and nitrite intake and thyroid cancer risk overall and for subtypes in the National Institutes of Health-American Association of Retired Persons (NIH-AARP) Diet and Health Study, a large prospective cohort of 490,194 men and women, ages 50-71 years in 1995-1996. Dietary intakes were assessed using a 124-item food frequency questionnaire. During an average of 7 years of follow-up we identified 370 incident thyroid cancer cases (170 men, 200 women) with complete dietary information. Among men, increasing nitrate intake was positively associated with thyroid cancer risk (relative risk [RR] for the highest quintile versus lowest quintile RR = 2.28, 95% confidence interval [CI]: 1.29-4.041; p-trend cancer for either men or women. We evaluated risk for the two main types of thyroid cancer. We found positive associations for nitrate intake and both papillary (RR = 2.10; 95% CI: 1.09-4.05; p-trend = 0.05) and follicular thyroid cancer (RR = 3.42; 95% CI: 1.03-11.4; p-trend = 0.01) among men. Nitrite intake was associated with increased risk of follicular thyroid cancer (RR = 2.74; 95%CI: 0.86-8.77; p-trend = 0.04) among men. Our results support a role of nitrate in thyroid cancer risk and suggest that further studies to investigate these exposures are warranted. Published 2010 UICC.

  2. Dietary patterns as identified by factor analysis and colorectal cancer among middle-aged Americans.

    Science.gov (United States)

    Flood, Andrew; Rastogi, Tanuja; Wirfält, Elisabet; Mitrou, Panagiota N; Reedy, Jill; Subar, Amy F; Kipnis, Victor; Mouw, Traci; Hollenbeck, Albert R; Leitzmann, Michael; Schatzkin, Arthur

    2008-07-01

    Although diet has long been suspected as an etiological factor for colorectal cancer, studies of single foods and nutrients have provided inconsistent results. We used factor analysis methods to study associations between dietary patterns and colorectal cancer in middle-aged Americans. Diet was assessed among 293,615 men and 198,767 women in the National Institutes of Health-AARP Diet and Health Study. Principal components factor analysis identified 3 primary dietary patterns: a fruit and vegetables, a diet foods, and a red meat and potatoes pattern. State cancer registries identified 2151 incident cases of colorectal cancer in men and 959 in women between 1995 and 2000. Men with high scores on the fruit and vegetable pattern were at decreased risk [relative risk (RR) for quintile (Q) 5 versus Q1: 0.81; 95% CI: 0.70, 0.93; P for trend = 0.004]. Both men and women had a similar risk reduction with high scores on the diet food factor: men (RR: 0.82; 95% CI: 0.72, 0.94; P for trend = 0.001) and women (RR: 0.87; 95% CI: 0.71, 1.07; P for trend = 0.06). High scores on the red meat factor were associated with increased risk: men (RR: 1.17; 95% CI: 1.02, 1.35; P for trend = 0.14) and women (RR: 1.48; 95% CI: 1.20, 1.83; P for trend = 0.0002). These results suggest that dietary patterns characterized by a low frequency of meat and potato consumption and frequent consumption of fruit and vegetables and fat-reduced foods are consistent with a decreased risk of colorectal cancer.

  3. Trends in the Incidence of Cervical Cancer in Jordan, 2000–2013

    Directory of Open Access Journals (Sweden)

    Ghazi Sharkas

    2017-01-01

    Full Text Available Objectives. To determine the incidence of cervical cancer in Jordan and assess its trend in over a 14-year period (2000–2013. Methods. This descriptive study was based on secondary analysis of cervical cancer data that are registered in the Jordan Cancer Registry (JCR. Results. A total of 591 women were diagnosed with cervical cancer in Jordan during the period 2000–2013. The age at diagnosis ranged between 15 and 97 years, with a median of 50 years. The average age standardized rate (ASR was 2.0/100,000 women. The incidence of cervical cancer started to decrease after 2006 but it remained relatively constant between 2008 and 2013. Over the 14-year period, ASR for cervical cancer decreased by 28.6% from 2.1 per 100,000 women in 2000 to 1.5 per 100,000 women in 2013. About 46.5% of the cases were of squamous cell carcinoma morphology. Early cancer constituted about 60% of the cases, regional cases constituted 9.6%, and distant metastatic cases constituted 10.7%. Conclusions. The incidence of cervical cancer in Jordan is low compared to regional estimates and remained relatively constant between 2008 and 2013. Implementation of screening measures could lead to better case finding, early diagnosis, and prevention of cervical cancer.

  4. Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1995 quality program status report

    International Nuclear Information System (INIS)

    Bolivar, S.L.

    1996-07-01

    This status report summarizes the activities and accomplishments of the Los Alamos National Laboratory Yucca Mountain Site Characterization Project's (YMP's) quality assurance program for January 1 to September 30, 1995. The report includes major sections on program activities and trend analysis

  5. Thyroid cancer in children and adolescents in Ukraine after the Chernobyl accident (1986-1995)

    International Nuclear Information System (INIS)

    Tronko, N.; Bogdanova, T.; Komissarenko, I.; Bolshova, E.; Oleynik, V.; Tereshchenko, V.; Epshtein, Y.; Chebotarev, V.

    1996-01-01

    The increase in the incidence of thyroid cancers in children and adolescents in Ukraine following the Chernobyl accident made it necessary to compile a clinical morphological register of respective cancers. In 1986-1994 there were 339 cases registered in children and adolescents, of them 211 children (who were operated at the age under 15 years) and 128 adolescents (who were operated at the age of 15-18 years). Before the Chernobyl accident (1981-1985) in Ukraine 59 cases of thyroid cancer in children and adolescents were reported: 25 cases in children and 34 cases in adolescents. This increase has been observed since 1990. In 1981-1985 the incidence rate (number of thyroid cancers per 100000 children population) ranged 0.04 - 0.06. In 1990 this estimate was 0.23 and in 1992-1994 0.36 - 0.43, thus a 7-10 fold increase exceeding the pre-Chernobyl level. In the 5 most contaminated northern regions of Ukraine (Kiev, Chernigov, Zhitomir, Cherkassy, Rovno regions) and the city of Kiev the incidence rate was much higher. For example, in 1984 it was 3.8 in Chernigov region, 1.6 in Zhitomir region. The total 'contribution' of the above-mentioned regions to the incidence of thyroid cancer in children after the Chernobyl accident makes more than 60%. It has been noted that in 1990-1994 there was an increase in the number of children operated at the age under 10, it means that these children were under 6 years at the time of the accident and were most sensitive to radioiodine exposure. As for the sex ratio, there has been a shift to males: in 1981-1985 F/M = 1.8/1, in 1990-1994 F/M = 1.4/1. Morphologically, 93.4% of 196 carcinomas resected from children and adolescents at the Institute of Endocrinology from 1986 to August 1st, 1995 were papillary carcinomas. They manifested high invasive and infiltrative growth, signs of intraglandular spread. Regional lymph node metastases were found in 59% of cases, distal lung metastases observed at various periods after surgery were noted

  6. Partnering Research Involving Mentoring and Education (PRIME) in Prostate Cancer

    Science.gov (United States)

    2008-08-01

    to the Profession of Nursing 1995-1996 Albert Schweitzer Fellowship 1995-1997 Lineberger Comprehensive Cancer Center, University of North Carolina...cancer prevention and early detection in African Americans; and Using the Albert Schweitzer fellowship program to foster cross-cultural experiences for...In North Carolina for Outstanding Contributions to the Profession of Nursing 1995-1996 Albert Schweitzer Fellowship 1995-1997 Lineberger

  7. 1973-1975 progress report

    International Nuclear Information System (INIS)

    This report is a survey of the work done at the CSNSM during the years 1973-1975. Two important parts are studied: firstly in nuclear spectrometry section: radioelements study and neutron activation analysis and datation used for archeology, atomic effects bound to nuclear transitions and heavy-ion reactions; secondly in mass spectrometry section; on-line mass spectrometry, super-heavy elements search in nature, nuclear astrophysics and technical developments in isotopes separators and ion implantation [fr

  8. Temporal trends in management and outcomes of testicular cancer: A population-based study.

    Science.gov (United States)

    Leveridge, Michael J; Siemens, D Robert; Brennan, Kelly; Izard, Jason P; Karim, Safiya; An, Howard; Mackillop, William J; Booth, Christopher M

    2018-04-16

    Treatment guidelines for early-stage testicular cancer have increasingly recommended de-escalation of therapy with surveillance strategies. This study was designed to describe temporal trends in routine clinical practice and to determine whether de-escalation of therapy is associated with inferior survival in the general population. The Ontario Cancer Registry was linked to electronic records of treatment to identify all patients diagnosed with testicular cancer treated with orchiectomy in Ontario during 2000-2010. Treatment after orchiectomy was classified as radiotherapy (RT), retroperitoneal lymph node dissection (RPLND), chemotherapy, or none. Surveillance was defined as no identified treatment within 90 days of orchiectomy. Overall survival (OS) and cancer-specific survival (CSS) were measured from the date of orchiectomy. The study population included 1564 and 1086 cases of seminomas and nonseminoma germ cell tumors (NSGCTs), respectively. Among patients with seminomas, there was a significant increase in the proportion of patients with no treatment within 90 days of orchiectomy (from 56% to 84%; P testicular cancer in routine practice since 2000. Long-term survival in routine practice is excellent and has not decreased with the uptake of surveillance strategies. Cancer 2018. © 2018 American Cancer Society. © 2018 American Cancer Society.

  9. Epidemiology of road traffic incidents in Peru 1973-2008: incidence, mortality, and fatality.

    Science.gov (United States)

    Miranda, J Jaime; López-Rivera, Luis A; Quistberg, D Alex; Rosales-Mayor, Edmundo; Gianella, Camila; Paca-Palao, Ada; Luna, Diego; Huicho, Luis; Paca, Ada

    2014-01-01

    The epidemiological profile and trends of road traffic injuries (RTIs) in Peru have not been well-defined, though this is a necessary step to address this significant public health problem in Peru. The objective of this study was to determine trends of incidence, mortality, and fatality of RTIs in Peru during 1973-2008, as well as their relationship to population trends such as economic growth. Secondary aggregated databases were used to estimate incidence, mortality and fatality rate ratios (IRRs) of RTIs. These estimates were standardized to age groups and sex of the 2008 Peruvian population. Negative binomial regression and cubic spline curves were used for multivariable analysis. During the 35-year period there were 952,668 road traffic victims, injured or killed. The adjusted yearly incidence of RTIs increased by 3.59 (95% CI 2.43-5.31) on average. We did not observe any significant trends in the yearly mortality rate. The total adjusted yearly fatality rate decreased by 0.26 (95% CI 0.15-0.43), while among adults the fatality rate increased by 1.25 (95% CI 1.09-1.43). Models fitted with splines suggest that the incidence follows a bimodal curve and closely followed trends in the gross domestic product (GDP) per capita. The significant increasing incidence of RTIs in Peru affirms their growing threat to public health. A substantial improvement of information systems for RTIs is needed to create a more accurate epidemiologic profile of RTIs in Peru. This approach can be of use in other similar low and middle-income settings to inform about the local challenges posed by RTIs.

  10. Epidemiology of road traffic incidents in Peru 1973-2008: incidence, mortality, and fatality.

    Directory of Open Access Journals (Sweden)

    J Jaime Miranda

    Full Text Available The epidemiological profile and trends of road traffic injuries (RTIs in Peru have not been well-defined, though this is a necessary step to address this significant public health problem in Peru. The objective of this study was to determine trends of incidence, mortality, and fatality of RTIs in Peru during 1973-2008, as well as their relationship to population trends such as economic growth.Secondary aggregated databases were used to estimate incidence, mortality and fatality rate ratios (IRRs of RTIs. These estimates were standardized to age groups and sex of the 2008 Peruvian population. Negative binomial regression and cubic spline curves were used for multivariable analysis. During the 35-year period there were 952,668 road traffic victims, injured or killed. The adjusted yearly incidence of RTIs increased by 3.59 (95% CI 2.43-5.31 on average. We did not observe any significant trends in the yearly mortality rate. The total adjusted yearly fatality rate decreased by 0.26 (95% CI 0.15-0.43, while among adults the fatality rate increased by 1.25 (95% CI 1.09-1.43. Models fitted with splines suggest that the incidence follows a bimodal curve and closely followed trends in the gross domestic product (GDP per capita.The significant increasing incidence of RTIs in Peru affirms their growing threat to public health. A substantial improvement of information systems for RTIs is needed to create a more accurate epidemiologic profile of RTIs in Peru. This approach can be of use in other similar low and middle-income settings to inform about the local challenges posed by RTIs.

  11. Franz Petrak, 1886—1973

    NARCIS (Netherlands)

    Arx, von J.A.

    1976-01-01

    Dr. F. Petrak passed away on October 9, 1973 in Vienna at the age of 87 years. He was born on October 9, 1886 in Mährisch-Weisskirchen, at that time a small town in the Moravian province of the Austrian Monarchy, but now belonging to the CSSR under the Czech name Hranice. A gift of some books,

  12. Monitoring of radioactivity in 1973

    International Nuclear Information System (INIS)

    Data are presented on the monitoring of radioactive contamination of air and some foodstuffs at world (locations throughout Western South America, South Pacific, Africa during 1973. Data are included on the total β and γ activity and content of radionuclides found in fallout in air, milk and other environmental samples ( 131 I, 90 Sr, 137 Cs) [fr

  13. Diagnosis, clinical staging, and treatment of breast cancer: a retrospective multiyear study of a large controlled population.

    Science.gov (United States)

    Legorreta, Antonio P; Chernicoff, Helen O; Trinh, Jennifer B; Parker, Robert G

    2004-04-01

    This study compares diagnosis, staging, and treatment of newly diagnosed breast cancer cases over a several-year period. The study design was a retrospective, multiyear comparison between new breast cancer cases diagnosed in 1995 (n = 827) and 1997 (n = 815). Cases were identified through claims data, and medical record abstraction was used to verify each case and to identify clinical staging and type of treatment. All medical records were reviewed by one physician to maximize internal reliability. Both cohorts were predominantly 40 and older, white, married, and postmenopausal. The latter cohort (1997) had a higher proportion of women aged 70 to 79 and a lower proportion of women aged 40 to 49. In both cohorts, women age 40 and older were likely to be diagnosed with breast cancer at the time of mammographic screening, while women younger than 40 were more likely to be diagnosed by clinical breast examination. In logistic regression analyses, controlling for confounding factors such as age, undergoing mammographic screening increased the likelihood of having a low cancer stage at diagnosis by more than three and a half times. Mammographic screening was statistically significantly positively associated with having eligibility for breast-conserving treatment (BCT); however, although an increase in BCT eligibility was observed, actual use of BCT did not change. Mammography leads to a lower clinical stage as well as a greater likelihood of BCT eligibility at time of breast cancer diagnosis, but may not have a substantial effect on treatment choice (lumpectomy vs. mastectomy). Between 1995 and 1997, a trend was observed toward downstaging of disease at diagnosis; further research is warranted to observe whether this trend continues over time.

  14. Less overdiagnosis of kidney cancer? an age-period-cohort analysis of incidence trends in 16 populations worldwide.

    Science.gov (United States)

    Znaor, Ariana; Laversanne, Mathieu; Bray, Freddie

    2017-09-01

    The increasing rates of kidney cancer incidence, reported in many populations globally, have been attributed both to increasing exposures to environmental risk factors, as well as increasing levels of incidental diagnosis due to widespread use of imaging. To better understand these trends, we examine long-term cancer registry data worldwide, focusing on the roles of birth cohort and calendar period, proxies for changes in risk factor prevalence and detection practice respectively. We used an augmented version of the Cancer Incidence in Five Continents series to analyze kidney cancer incidence rates 1978-2007 in 16 geographically representative populations worldwide by sex for ages 30-74, using age-period-cohort (APC) analysis. The full APC model provided the best fit to the data in most studied populations. While kidney cancer incidence rates have been increasing in successive generations born from the early twentieth century in most countries, equivalent period-specific rises were observed from the late-1970s, although these have subsequently stabilized in certain European countries (the Czech Republic, Lithuania, Finland, Spain) as well as Japan from the mid-1990s, and from the mid-2000s, in Colombia, Costa Rica and Australia. Our results indicate that the effects of both birth cohort and calendar period contribute to the international kidney cancer incidence trends. While cohort-specific increases may partly reflect the rising trends in obesity prevalence and the need for more effective primary prevention policies, the attenuations in period-specific increases (observed in 8 of the 16 populations) highlight a possible change in imaging practices that could lead to mitigation of overdiagnosis and overtreatment. © 2017 UICC.

  15. Mexico's Federal Education Law of 1973; Its Implications for Nonformal Education.

    Science.gov (United States)

    Dobson-Ingram, John R. A.

    An evolutionary step in Mexico's nonformal educational development, the Federal Education Law of 1973 was ratified by the President in December 1973. This law covers the purpose of education in Mexico, the national system of education, distribution of responsibilities for education, programs of study, rights and obligations of institutions,…

  16. Dose trend analysis of the PWR nuclear power plants

    International Nuclear Information System (INIS)

    Cernilogar Radez, M.; Janzekovic, H.; Krizman, M.

    2002-01-01

    The analyses of occupational dose trends in Krsko NPP in the period from 1995 to 2001 are given in comparison to the worldwide data. The Central Dose Register of Workers in Nuclear Installations at the Slovenian Nuclear Safety Administration enables the comprehensive dose trend analysis of the occupational doses in Krsko NPP. The time dose trend of the collective annual effective dose at the Krsko NPP shows somehow different trend than the trends of the ISOE data [1]. The performance indicators describing dose data distributions related to the radiation protection standards [2, 3] are discussed.(author)

  17. RA Research reactor, Annual report 1973; Istrazivacki nuklearni reaktor RA - Izvestaj za 1973. godinu - Pogon i odrzavanje

    Energy Technology Data Exchange (ETDEWEB)

    Milosevic, D et al. [Institute of Nuclear Sciences Boris Kidric, Vinca, Beograd (Serbia and Montenegro)

    1973-12-15

    During 1973, RA reactor was operated at nominal power for 4687 hours and 54 hours at lower power levels. The total production was 30504 MWh which is 1.6% higher than planned. Practically there was no discrepancies from the plan, since the action plan was corrected at the beginning of this year caused by the demand of changing the schedule for refuelling for the purpose of 'power excursion' experiment. The reactor was used for irradiation and experiments according to the demand of 336 users. This report contains detailed data about reactor power and experiments performed in 1973. Total number safety shutdowns was 12, of which 7 were caused by power cuts. Three shutdowns caused by failures of the equipment were caused by failures of new electronic tubes. Two shutdowns were caused by the operators. There have been three shorter interruptions announced power cuts. Total personnel exposure dose was lower than during previous years. There were no accidents during this year. Decontamination of surfaces was less than during previous years. Practically there was no surface contamination, and the quantity of collected radioactive waste was lower than previously. There were no liquid radioactive effluents. It was concluded that the successful operation in 1973 has a special significance taking into account the financial crisis. There still remains a number of unsolved problems related to: completing the inventory of spare parts, exchange of some elements of the equipment, exchange of instrumentation, and purchase of the highly enriched fuel. [Serbo-Croat] Reaktor RA je u 1973. godini radio na nominalnoj snazi 4687 sati i 54 sata na manjim snagama. Ukupni rad iznosio je 30504 MWh odnosno 1,6% vise od planiranog. Prakticno nije bilo odstupanja od plana rada koji je pocetkom godine korigovan zbog promene planiranih izmena goriva usled izvodjenja eksperimenta 'ekskurzije snage'. Reaktor je koriscen za ozracivanja i eksperimente za 336 korisnika. Ovaj izvestaj sadrzi detaljne

  18. Physical, chemical and biological data, Tasaday Expedition, Legs I, II, III and IV : Leg I, 5 June-1 July 1973; Leg II, 8-15 July 1973; Leg III, 22 July-4 August 1973; Leg IV, 13 August-6 September 1973 (NODC Accession 9200047)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Tasaday expedition aboard RV Thomas Washington was a multidisciplinary oceanographic expedition in the Pacific and Indian Ocean during 1973-1974. This report...

  19. Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1995 quality program status report

    Energy Technology Data Exchange (ETDEWEB)

    Bolivar, S.L.

    1996-07-01

    This status report summarizes the activities and accomplishments of the Los Alamos National Laboratory Yucca Mountain Site Characterization Project`s (YMP`s) quality assurance program for January 1 to September 30, 1995. The report includes major sections on program activities and trend analysis.

  20. Cancer incidence in Fort Chipewyan, Alberta : 1995-2006

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Y. [Alberta Cancer Board, Edmonton, AB (Canada). Division of Population Health and Information Surveillance

    2009-02-15

    A high number of cases of cholangiocarcinoma, a rare form of bile duct cancer, as well as high rates of other cancers were reported by a physician working in Fort Chipewyan, Alberta in 2006. Concerns were raised by local residents, attributing cancers in their community to environmental contamination from a range of industrial development including the oil sands development, uranium mining and pulp mills. However, an initial review of the Alberta Cancer Registry did not confirm an increased incidence of cancer in Fort Chipewyan. In the summer/fall of 2007, a working group was formed to support the Alberta Cancer Board in doing a cluster investigation based on the guidelines of the United States Centre for Disease Control and Prevention. This report presented an investigation to determine if there was an elevated rate of cholangiocarcinoma in Fort Chipewyan and whether there was an elevated rate of cancers overall in Fort Chipewyan. The report provided background information on the Athabasca oil sands, uranium mining, and Fort Chipewyan as well as previous investigations of cancer incidence in Fort Chipewyan. Study methods were also presented with particular reference to study and comparison populations; cancer classification and inclusion criteria; active case ascertainment and verification; methods of analysis; and ethical approval. Results were also presented. The specific cancers that were discussed were cholangiocarcinoma, leukemia, colon cancer, and cancer in First Nations in Alberta. It was concluded that the observed number of cases of cholangiocarcinoma was within the expected range. 121 refs., 12 tabs., 3 figs., 5 appendices.

  1. Energy supply and demand result in fiscal 1995 and a short-term prospect. Report submitted by the energy supply and demand trend investigation committee; 1995 nendo energy jukyu jisseki to tanki tenbo. Energy jukyu doko chosa iinkai hokoku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    This paper describes the energy demand and supply result in fiscal 1995 and a short-term prospect. The business condition in Japan is regaining some brightness. While the net GDP growth has stayed at 0.9%, the domestic primary energy supply has increased by 2.9% and the final energy consumption by 3.2% over the previous year, respectively. The energy consumption has increased by 3.7% with the background of increase in production levels in the industrial department in material industries induced by external demand. The consumer department showed as high growth as 5.1% centering on household room heating due to cold winter. The business and transportation departments presented an increase of 2.2% and 2.4%, respectively. Sharp growth of 3.0% was shown in the net GDP during January through March, 1996, having the net GDP growth rate for fiscal 1995 escaped from zero growth that has lasted three years. The recovery of the domestic business condition is moving gradually centering on the consumer demand, wherein the point to be focused from now on is how much the recovery can compensate for decline in the public demand and reduction in the external demand. Attention is given on path of the business condition recovery and future trends in energy demand under the situation of risen consumption tax and deregulated oil business. 42 figs., 73 tabs.

  2. Disparities in dietary habits and physical activity in Denmark and trends from 1995 to 2008.

    Science.gov (United States)

    Groth, Margit Velsing; Sørensen, Mette Rosenlund; Matthiessen, Jeppe; Fagt, Sisse; Landvad, Niels; Knudsen, Vibeke Kildegaard

    2014-11-01

    To examine social disparities in dietary-, alcohol- and leisure-time physical activity habits in Danish adults from 1995 to 2008 and to test the hypothesis of widening disparities. Four cross-sectional surveys of representative samples of the Danish population aged 20-75 years were analysed, a total of 7900 respondents. Dietary and alcohol habits were measured by a 7-day pre-coded food diary and physical activity and education by a face-to-face interview. Multivariate analyses were used to test associations between explanatory variables and response variables and the hypothesis of widening disparities. In all analyses, both diet quality and physical inactivity differed systematically with educational group and with healthier habits for the group with long education. Only for alcohol habits was an opposite social gradient seen. Disparities persisted over all time periods. The analyses using "The Concentration Index" did not change any of the conclusions. Gender also influenced diet quality. Men had dietary and alcohol habits furthest away from the guidelines. A trend of healthier habits was also found over the time period. Social disparities in diet quality and leisure-time physical activity were seen for all examined time periods and with no significant change therefore, there is no support to the hypothesis of widening social disparities in all educational groups some improvement of dietary habits was found, especially for those foods where comprehensive initiatives had taken place however, social disparities still exist there is an ongoing need to address these disparities in order to reduce social inequality in health. © 2014 the Nordic Societies of Public Health.

  3. Annual report 1973

    International Nuclear Information System (INIS)

    Krause, H.; Rudolph, G.

    1975-05-01

    This is a report on the activities of the Decontamination Service of the Nuclear Research Centre Karlsruhe in 1973. The emphasis regarding research and development work is put on the fixation of radioactive concentrates into bitumens, the vitrification of high level waste from reprocessing plants, the testing of a pilot plant for the vitrification, radioactive waste transport and ultimate storage, studies concerning the contamination of reactor coolant loops, and the decontamination of water and materials. The projects in hand by the Service as well as the activities of the operating group are described. (RB/LN) [de

  4. Childhood cancer survival in Switzerland (1976-2013): Time-trends and predictors.

    Science.gov (United States)

    Schindler, Matthias; Belle, Fabiën N; Grotzer, Michael A; von der Weid, Nicolas X; Kuehni, Claudia E

    2017-01-01

    Population-based studies on childhood cancer survival are key to monitor progress against cancer and to detect potential differences between regions and other subgroups in the population. We investigated time trends and factors associated with childhood cancer survival on a national level in Switzerland, from 1976 to 2013. We extracted data from the population-based Swiss Childhood Cancer Registry of 5,776 children (age 0-14 years) diagnosed with cancer from 1985 to 2014 in Switzerland. We calculated age-adjusted 5-year survival, defined the annual reduction in risk of death (ARR), and explored associations of survival with clinical and demographic factors. Overall, 5-year survival improved significantly, from 64% in 1976-1983 to 88% in 2004-2013. ARR over the whole period was 4% for all diagnostic groups, greatest for Hodgkin lymphomas (8%), ependymomas (6%), Burkitt's lymphomas (6%) and germ cell tumours (6%). Children treated in hospitals without specialised paediatric cancer centre for leukaemia (HR 12.9), lymphoma (HR 5.0) and neuroblastoma (HR 3.7) were at higher risk of death. In French-speaking Switzerland, risk of death was lower for lymphoma (HR 0.6), CNS tumours (HR 0.7) and neuroblastoma (HR 0.5). Children with migration background had a higher risk of death from all tumours except bone tumours. Childhood cancer survival significantly improved from 1976 to 2013, but there is room for further improvement. Survival rates varied by type of clinical treatment, language region and nationality. All paediatric cancer patients should be referred to a specialised paediatric cancer centre. Further research is needed to intervene and completely eliminate inequalities in survival. © 2016 UICC.

  5. Long-term trends and survival analysis of esophageal and gastric cancer in Yangzhong, 1991-2013.

    Directory of Open Access Journals (Sweden)

    Zhaolai Hua

    Full Text Available To describe the long-term trends of the incidence, mortality and survival of upper digestive tract cancers in a high-risk area of China.We extracted esophageal and gastric cancer cases diagnosed from 1991 to 2013 through the Yangzhong Cancer Registry and calculated the crude and age-standardized incidence and mortality rates. Cancer trends were calculated using the Joinpoint Regression Program and were reported using the annual percentage change (APC. The cancer-specific survival rates were evaluated and compared between groups using the Kaplan-Meier method and log-rank test.The age-standardized incidence rate of esophageal cancer declined from 107.06 per 100,000 person-years (male: 118.05 per 100,000 person-years; female: 97.42 per 100,000 person-years in 1991 to 37.04 per 100,000 person-years (male: 46.43 per 100,000 person-years; female: 27.26 per 100,000 person-years in 2013, with an APC of -2.5% (95% confidence interval (CI: -3.4%, -1.5% for males and -4.9% (95% CI:-5.8%, -3.9% for females. The age-standardized incidence rate of gastric cancer was 165.11 per 100,000 person-years (male: 225.39 per 100,000 person-years; female: 113.34 per 100,000 person-years in 1991 and 53.46 per 100,000 person-years (male: 76.51 per 100,000 person-years; female: 32.43 per 100,000 person-years in 2013, with the APC of -3.6% (95% CI: -4.5%, -2.7% for males and -4.8% (95% CI: -5.7%, -3.9% for females. The median survival time was 3.0 years for patients with esophageal or gastric cancer. Cancer cases detected after 2004 had a better prognosis.The age-standardized incidence rates of both esophageal and gastric cancer continuously decreased since 1991 through 2013, whereas the mortality rate remained stable before 2004 and significantly declined following the massive endoscopic screening program initiated in 2004. The survival probability of patients with esophageal and gastric cancer has improved obviously in recent decades.

  6. Trends in cancer of the urinary bladder and urinary tract in elderly in Denmark, 2008-2012

    DEFF Research Database (Denmark)

    Jensen, Thor Knak; Jensen, Niels Viggo; Jørgensen, Simon Møller

    2016-01-01

    Background The aim of this study was to examine the trends in incidence, mortality, survival, and prevalence of cancers of the urinary bladder and urinary tract in Denmark from 1980 to 2012 with particular focus on elderly patients over age 70 years. Design Cancer of the urinary bladder and urinary...... tract was defined as ICD-10 codes C67.9, D09.0, D41.4. Data were derived from the NORDCAN database with comparable data on cancer incidence, mortality, prevalence and relative survival in the Nordic countries, where the Danish data were delivered from the Danish Cancer Registry and the Danish Cause...

  7. Breast cancer incidence and mortality in the Nordic capitals, 1970-1998. Trends related to mammography screening programmes

    International Nuclear Information System (INIS)

    Toernberg, Sven; Kemetli, Levent; Anttila, Ahti; Hakama, Matti; Nystroem, Lennarth

    2006-01-01

    The aim of the present study was to relate the time trends in breast cancer incidence and mortality to the introduction of mammography screening in the Nordic capitals. Helsinki offered screening to women aged 50-59 starting in 1986. The other three capitals offered screening to women aged 50-69 starting in 1989 in Stockholm, 1991 in Copenhagen, and 1996 in Oslo. Prevalence peaks in breast cancer incidence depended on the age groups covered by the screening, the length of the implementation of screening, and the extent of background opportunistic screening. No mortality reduction following the introduction of screening was visible after seven to 12 years of screening in any of the three capitals where significant effects of the screening on the breast cancer mortality had already been demonstrated by using other analytical methods for the evaluation. No visible effect on mortality reduction was expected in Oslo due to too short an observation period. The study showed that the population-based breast cancer mortality trend is too crude a measure to detect the effect of screening on breast cancer mortality during the first years after the start of a programme

  8. Trends in net survival from prostate cancer in six European Latin countries: results from the SUDCAN population-based study.

    Science.gov (United States)

    Grosclaude, Pascale; Roche, Laurent; Fuentes-Raspall, Rafael; Larrañaga, Nerea

    2017-01-01

    Cancer survival is a key measure of the effectiveness of a health-care system. European Latin countries have some differences in their health system; therefore, it is of interest to compare them in terms of survival from cancer. Prostate cancer data from six countries (Belgium, France, Italy, Portugal, Spain, and Switzerland) were extracted from the EUROCARE-5 database (end of follow-up: 1 January 2009). First, the net survival (NS) was studied over the 2000-2004 period using the Pohar-Perme estimator. For trend analyses, the study period was specific to each country. Trends in NS over the 1989-2004 period and changes in the pattern of cancer excess mortality rate until 5 years after the diagnosis were examined using a multivariate excess mortality rate model. A striking increase in survival from prostate cancer occurred in European Latin countries at all ages studied. In the last period of the study, there was little difference in age-standardized NSs from prostate cancer between the six countries. The trends of the survival followed those of the incidence (except in Spain in the elderly); the increases in incidence were the highest at ages 60-70 years and, in the elderly (around 80 years), the incidence did not increase in Switzerland. The increases in NS can mainly be explained by lead-time and overdiagnosis effects. The epidemiological interpretability of the changes in prostate cancer survival in Latin countries is strongly compromised by the biases inherent to the extensive prostate-specific antigen testing.

  9. Investigation of mammographic breast density as a risk factor for ovarian cancer.

    Science.gov (United States)

    Wernli, Karen J; O'Meara, Ellen S; Kerlikowske, Karla; Miglioretti, Diana L; Muller, Carolyn Y; Onega, Tracy; Sprague, Brian L; Henderson, Louise M; Buist, Diana S M

    2014-01-01

    Endogenous hormones and growth factors that increase mammographic breast density could increase ovarian cancer risk. We examined whether high breast density is associated with ovarian cancer risk. We conducted a cohort study of 724,603 women aged 40 to 79 years with 2,506,732 mammograms participating in the Breast Cancer Surveillance Consortium from 1995 to 2009. Incident epithelial ovarian cancer was diagnosed in 1373 women. We used partly conditional Cox regression to estimate the association between breast density and 5-year risk of incident epithelial ovarian cancer overall and stratified by 10-year age group. All statistical tests were two-sided. Compared with women with scattered fibroglandular densities, women with heterogeneously dense and extremely dense breast tissue had 20% and 18% increased 5-year risk of incident epithelial ovarian cancer (hazard ratio [HR] = 1.20, 95% confidence interval [CI] = 1.06 to 1.36; HR = 1.18, 95% CI = 0.93 to 1.50, respectively; P(trend) = .01). Among women aged 50 to 59 years, we observed a trend in elevated risk associated with increased breast density (P(trend) = .02); women with heterogeneously and extremely dense breast tissue had 30% (HR = 1.30; 95% CI = 1.03 to 1.64) and 65% (HR = 1.65; 95% CI = 1.12 to 2.44) increased risk, respectively, compared with women with scattered fibroglandular densities. The pattern was similar but not statistically significant at age 40 to 49 years. There were no consistent patterns of breast density and ovarian cancer risk at age 60 to 79 years. Dense breast tissue was associated with a modest increase in 5-year ovarian cancer risk in women aged 50 to 59 years but was not associated with ovarian cancer at ages 40 to 49 or 60 to 79 years.

  10. Prevalence and histopathology of Neoechinorhynchus curemai Noronha, 1973 (Acanthocephala: Neoechinorhynchidae in Prochilodus lineatus Valenciennes, 1836 from Volta Grande Reservoir, MG, Brazil

    Directory of Open Access Journals (Sweden)

    M. L. MARTINS

    Full Text Available The present work studied the prevalence and histopathology of Neoechinorhynchus curemai Noronha, 1973 (Acanthocephala: Neoechinorhynchidae from curimbatá, Prochilodus lineatus Valenciennes, 1836. Eighteen fishes with averages of 46.7 + 1.1 cm length and 1,674.8 + 75.6 g weight were collected with net, bimonthly from December 1995 thru December 1996 in the hydroelectric power station of Volta Grande Reservoir (Cemig, Minas Gerais, Brazil. From analysed fishes, 15 were infected with acanthocephalans in the intestine (prevalence 83.3%. The greatest mean intensity occurred in August 1996 with 66.5 (16 to 208 parasites. Histopathological analysis showed complete desquamation of the intestinal epithelium with severe hyperplasia and hypertrofia of the goblet cells. Severe inflammatory reaction at the submucosa, displacement of their sheaf, associated with oedema and mononuclear and eosinophilic infiltration were observed.

  11. Divergent oestrogen receptor-specific breast cancer trends in Ireland (2004-2013): Amassing data from independent Western populations provide etiologic clues.

    Science.gov (United States)

    Mullooly, Maeve; Murphy, Jeanne; Gierach, Gretchen L; Walsh, Paul M; Deady, Sandra; Barron, Thomas I; Sherman, Mark E; Rosenberg, Philip S; Anderson, William F

    2017-11-01

    The aetiology and clinical behaviour of breast cancers vary by oestrogen receptor (ER) expression, HER2 expression and over time. Data from the United States and Denmark show rising incidence rates for ER+ and falling incidence rates for ER- breast cancers. Given that Ireland is a somewhat similar Western population but with distinctive risk exposures (especially for lactation), we analysed breast cancer trends by ER status; and for the first time, by the joint expression of ER±/HER2±. We assessed invasive breast cancers (n = 24,845; 2004-2013) within the population-based National Cancer Registry of Ireland. The population at risk was obtained from the Irish Central Statistics Office (n = 10,401,986). After accounting for missing ER and HER2 data, we assessed receptor-specific secular trends in age-standardised incidence rates (ASRs) with the estimated annual percentage change (EAPC) and corresponding 95% confidence intervals (95% CI). Age-period-cohort models were also fitted to further characterise trends accounting for age, calendar-period and birth-cohort interactions. ASRs increased for ER+ (EAPC: 2.2% per year [95% CI: 0.97, 3.45%/year]) and decreased for ER- cancers (EAPC: -3.43% per year [95% CI: -5.05, -1.78%/year]), as well as for specific age groups at diagnosis (rates among independent Western populations likely reflects calendar-period and/or risk factor changes with differential effects for ER+ and ER- breast cancers. Published by Elsevier Ltd.

  12. Trends in preterm birth in singleton deliveries in a Hong Kong population

    NARCIS (Netherlands)

    Hui, Annie S. Y.; Lao, Terence T.; Leung, Tak Yeung; Schaaf, Jelle M.; Sahota, Daljit S.

    2014-01-01

    To examine trends in preterm birth and its relationship with perinatal mortality in Hong Kong. In a retrospective cohort study, data were reviewed from singletons delivered between 1995 and 2011 at a university teaching hospital. Trends in preterm birth (between 24 and 36 weeks of pregnancy),

  13. International variation in lung cancer mortality rates and trends among women.

    Science.gov (United States)

    Torre, Lindsey A; Siegel, Rebecca L; Ward, Elizabeth M; Jemal, Ahmedin

    2014-06-01

    There is no recent comprehensive global analysis of lung cancer mortality in women. We describe contemporary mortality rates and trends among women globally. We used the World Health Organization's Cancer Mortality Database covering 65 populations on six continents to calculate age-standardized (1960 Segi world standard) lung cancer death rates during 2006 to 2010 and annual percent change in rates for available years from 1985 to 2011 and for the most recent five data years by population and age group (30-49 and 50-74 years). Lung cancer mortality rates (per 100,000) among young women (30-49 years) during 2006 to 2010 ranged from 0.7 in Costa Rica to 14.8 in Hungary. Rates among young women were stable or declining in 47 of 52 populations examined. Rates among women 50 to 74 years ranged from 8.8 in Georgia and Egypt to 120.0 in Scotland. In both age groups, rates were highest in parts of Europe (Scotland, Hungary, Denmark) and North America and lowest in Africa, Asia, and Latin America. Rates in older women were increasing for more than half (36/64) of populations examined, including most countries in Southern, Eastern, and Western Europe and South America. Although widespread reductions in lung cancer in young women provide evidence of tobacco control success, rates continue to increase among older women in many countries. More concentrated efforts to initiate or expand tobacco control programs in these countries globally will be required to attenuate the future lung cancer burden. Cancer Epidemiol Biomarkers Prev; 23(6); 1025-36. ©2014 AACR. ©2014 American Association for Cancer Research.

  14. Occurrence of yeast bloodstream infections between 1987 and 1995 in five Dutch university hospitals

    NARCIS (Netherlands)

    A. Voss (Andreas); J.A.J.W. Kluytmans (Jan); J.G. Koeleman; L. Spanjaard (Lodewijk); C.M.J.E. Vandenbroucke-Grauls (Christina); H.A. Verbrugh (Henri); M.C. Vos (Margreet); A.Y.L. Weersink (A. Y L); J.A.A. Hoogkamp-Korstanje (J. A A); J.F. Meis

    1996-01-01

    textabstractThe aim of this study was to identify retrospectively trends in fungal bloodstream infections in The Netherlands in the period from 1987 to 1995. Results of over 395,000 blood cultures from five Dutch university hospitals were evaluated. Overall, there were more than 12 million patient

  15. State of Maine residential heating oil survey: 1995--1996 season summary

    International Nuclear Information System (INIS)

    Elder, B.

    1996-05-01

    In Maine the cash price is surveyed, as opposed to lthe retail or charge price, as it has been identified as the price most often paid by Maine consumers. As one can see from the chart in this report, the 1995-1996 cash prices for No. 2 heating oil can be characterized as having an upward trend and much more fluctuation than last years' relatively flat line. The 1995-96 heating season started at the closing price of the previous season and for the first few weeks prices were lower than most of the 1994-95 trendline. When the weather became cooler, however, prices were on a steady incline until well into the winter. Prices leveled off for most of the rest of the season with a dramatic surge on the last week of the survey. The average statewide cash price for No. 2 heating oil this year was .861 1 cents, approximately ten cents higher than the average for 1994-1995 which was .7661 cents per gallon. It has been the observation of the SPO that during most of the 1995-1996 season, Maine's prices showed a direct correspondence with New England rack or wholesale prices. It appeared that they never fluctuated more than 3-4 cents from each other

  16. Environmental radioactivity. Ispra 1973-1974

    International Nuclear Information System (INIS)

    Dominici, G.

    1976-01-01

    In this report there are briefly described the measurements of environmental radioactivity performed during 1973-1974 by the site survey group of the Protection Division of the Euratom Joint Research Centre - Ispra Establishment. Data are given on the concentrations of 90 Sr, 137 Cs and other radionuclides in precipitation, air, waters, herbage, milk and radioactive effluents. The environmental contamination is mainly world-wide fall out

  17. CHINA'S INTERNATIONAL TOURISM UNDER ECONOMIC TRANSITION: NATIONAL TRENDS AND REGIONAL DISPARITIES

    OpenAIRE

    Liang, Chyi-Lyi (Kathleen); Guo, Rong; Wang, Qingbin

    2003-01-01

    China's Tourism industry, especially international tourism, has expanded rapidly since its market-oriented economic reform started in 1978. There has been limited information regarding the trends and regional disparities. This paper examines the national trends of China's international tourism since 1982 and analyzes the changes in regional disparities since 1995. While the trend analysis suggests that China's international tourism is likely to keep growing at a significant rate, the analysis...

  18. Gastric cancer burden of last 40 years in North China (Hebei Province): A population-based study.

    Science.gov (United States)

    Liang, Di; Liang, Suoyuan; Jin, Jing; Li, Daojuan; Shi, Jin; He, Yutong

    2017-01-01

    Gastric cancer (GC) is the second leading cause of cancer death in China. It is well known that Cixian in Hebei Province is one of the highest risk areas of GC in China and worldwide. This study aims to accurate assessment of GC burden and trend in high-risk area (Hebei Province) from 1973 to 2013. The authors analyzed GC data from 21 population-based cancer registries which represented 15.25% of the entire population of Hebei Province. The collected data were stratified by 5-year age groups, gender, and area. Mortality of GC was extracted from national death surveys from 1973 to 1975, 1990 to 1992, 2004 to 2005, and 2011 to 2013. Trend analysis (1988-2013) in a high-risk area (Cixian) used the Joinpoint Model. The age-period-cohort model was used to estimate the effects of age, period, and birth cohort in GC incidence in Cixian from 1988 to 2013. The crude incidence of GC in 2011 to 2013 was 40.37/100,000 (57.53/100,000 in males and 22.55/100,000 in females). The corresponding age-standardized rate by world age-standard population was 32.18/100,000 (48.87/100,000 in males and 17.53/100,000 in females), which was 2.66-fold (2.81-fold in male and 2.34-fold in female) higher than that in the world (12.1/100,000, 17.4/100,000 in males and 7.5/100,000 in females). Males in rural areas had the highest incidence, with an age-standardized rate of 70.51/100,000. Gastric cardia cancer was primary anatomical subsite which accounting for 59.59% in GC, followed by gastric corpus (13.92%), gastric antrum (11.43%), gastric fundus (4.99%), and overlapping lesion of gastric (4.17%). The age-standardized rate of mortality from GC displayed a significant downward trend (P = 0.019) in Hebei Province from the 1990s (31.44/100,000) to the 2010s (24.63/100,000). In Cixian, the incidence of GC rose from 1988 (38.25/100,000) to 2009 (65.11/100,000). Cixian, where population-based screening of upper gastrointestinal cancer was performed, experienced the increasing rate of GC from 2000

  19. Trends in Obesity Prevalence in Adults With a History of Cancer: Results From the US National Health Interview Survey, 1997 to 2014.

    Science.gov (United States)

    Greenlee, Heather; Shi, Zaixing; Sardo Molmenti, Christine L; Rundle, Andrew; Tsai, Wei Yann

    2016-09-10

    Obesity after a diagnosis of specific cancers has been associated with worse prognosis. We examined the trend in obesity prevalence among cancer survivors in the United States in the past two decades and compared trends with those of adults without a history of cancer. This was a population-based nationally representative sample of 538,969 noninstitutionalized US adults 18 to 85 years old with and without a history of cancer who participated in annual cross-sectional National Health Interview Surveys from 1997 to 2014. Obesity was defined as body mass index ≥ 30 kg/m(2) for non-Asians and body mass index ≥ 27.5 kg/m(2) for Asians. Among 32,447 cancer survivors identified, the most common cancer diagnoses were breast (n = 6,948), prostate (n = 3,984), and colorectal (n = 2,546). From 1997 to 2014, the prevalence of obesity increased from 22.4% to 31.7% in cancer survivors and from 20.9% to 29.5% in adults without a history of cancer (P for trend history of cancer compared with those without a history of cancer (all P for interaction < .001). The estimated rate of annual increase in obesity prevalence was 3.1% in female and 3.7% in male colorectal cancer survivors, 3.0% in breast cancer survivors, and 2.1% in prostate cancer survivors (all P < .001). In subgroup analyses, populations with the highest rates of increasing obesity burden were colorectal cancer survivors, breast cancer survivors, and non-Hispanic blacks. From 1997 to 2014, obesity increased more rapidly among adult cancer survivors compared with the general population. Colorectal and breast cancer survivors and non-Hispanic blacks were identified as being at the highest risk for obesity. © 2016 by American Society of Clinical Oncology.

  20. Hospital-based colorectal cancer survival trend of different tumor locations from 1960s to 2000s.

    Directory of Open Access Journals (Sweden)

    Yu-Jing Fang

    Full Text Available BACKGROUND: Our aim is to explore the trend of association between the survival rates of colorectal cancer (CRC and the different clinical characteristics in patients registered from 1960s to 2000s. We hypothesized that the survival rate of CRC increases over time and varies according to anatomic subsites. METHODS: Information from a total of 4558 stage T(1-4N(1-2M0 CRC patients registered from 1960s to 2008 were analyzed. The association of CRC overall survival with age, gender, tumor locations, time, histopathology types, pathology grades, no. of examined lymph nodes, the T stage, and the N stage was analyzed. The assessment of the influence of prognostic factors on patient survival was performed using Cox's proportional hazard regression models. RESULTS: From 1960 to 2008, the studied CRC patients included 2625 (57.6% and 1933 (42.4% males and females, respectively. These included 1896 (41.6% colon cancers, and 2662 (58.4% rectum cancers. The 5-year survival rate was 49%, 58%, 58%, 70%, and 77% for the time duration of 1960s, 1970s, 1980s, 1990s and 2000s, respectively. An increased 5-year survival rate was observed in the colon cancer and rectum cancer patients. Patients older than 60 years of age were more likely to develop colonic cancer (sigmoid than rectum cancer (49.2% vs. 39.9%. The Cox regression model showed that only rectum cancer survival was related to time duration. CONCLUSION: The overall survival and 5-year survival rates showed an increase from the 1960s to 2000s. There is a trend of rightward shift of tumor location in CRC patients.

  1. Epidemiology of Road Traffic Incidents in Peru 1973–2008: Incidence, Mortality, and Fatality

    Science.gov (United States)

    Miranda, J. Jaime; López-Rivera, Luis A.; Quistberg, D. Alex; Rosales-Mayor, Edmundo; Gianella, Camila; Paca-Palao, Ada; Luna, Diego; Huicho, Luis; Paca, Ada; Luis, López; Luna, Diego; Rosales, Edmundo; Best, Pablo; Best, Pablo; Egúsquiza, Miriam; Gianella, Camila; Lema, Claudia; Ludeña, Esperanza; Miranda, J. Jaime; Huicho, Luis

    2014-01-01

    Background The epidemiological profile and trends of road traffic injuries (RTIs) in Peru have not been well-defined, though this is a necessary step to address this significant public health problem in Peru. The objective of this study was to determine trends of incidence, mortality, and fatality of RTIs in Peru during 1973–2008, as well as their relationship to population trends such as economic growth. Methods and Findings Secondary aggregated databases were used to estimate incidence, mortality and fatality rate ratios (IRRs) of RTIs. These estimates were standardized to age groups and sex of the 2008 Peruvian population. Negative binomial regression and cubic spline curves were used for multivariable analysis. During the 35-year period there were 952,668 road traffic victims, injured or killed. The adjusted yearly incidence of RTIs increased by 3.59 (95% CI 2.43–5.31) on average. We did not observe any significant trends in the yearly mortality rate. The total adjusted yearly fatality rate decreased by 0.26 (95% CI 0.15–0.43), while among adults the fatality rate increased by 1.25 (95% CI 1.09–1.43). Models fitted with splines suggest that the incidence follows a bimodal curve and closely followed trends in the gross domestic product (GDP) per capita Conclusions The significant increasing incidence of RTIs in Peru affirms their growing threat to public health. A substantial improvement of information systems for RTIs is needed to create a more accurate epidemiologic profile of RTIs in Peru. This approach can be of use in other similar low and middle-income settings to inform about the local challenges posed by RTIs. PMID:24927195

  2. Decreases in Smoking-Related Cancer Mortality Rates Are Associated with Birth Cohort Effects in Korean Men.

    Science.gov (United States)

    Jee, Yon Ho; Shin, Aesun; Lee, Jong-Keun; Oh, Chang-Mo

    2016-12-05

    Background: This study aimed to examine trends in smoking-related cancer mortality rates and to investigate the effect birth cohort on smoking-related cancer mortality in Korean men. Methods: The number of smoking-related cancer deaths and corresponding population numbers were obtained from Statistics Korea for the period 1984-2013. Joinpoint regression analysis was used to detect changes in trends in age-standardized mortality rates. Birth-cohort specific mortality rates were illustrated by 5 year age groups. Results: The age-standardized mortality rates for oropharyngeal decreased from 2003 to 2013 (annual percent change (APC): -3.1 (95% CI, -4.6 to -1.6)) and lung cancers decreased from 2002 to 2013 (APC -2.4 (95% CI -2.7 to -2.2)). The mortality rates for esophageal declined from 1994 to 2002 (APC -2.5 (95% CI -4.1 to -0.8)) and from 2002 to 2013 (APC -5.2 (95% CI -5.7 to -4.7)) and laryngeal cancer declined from 1995 to 2013 (average annual percent change (AAPC): -3.3 (95% CI -4.7 to -1.8)). By the age group, the trends for the smoking-related cancer mortality except for oropharyngeal cancer have changed earlier to decrease in the younger age group. The birth-cohort specific mortality rates and age-period-cohort analysis consistently showed that all birth cohorts born after 1930 showed reduced mortality of smoking-related cancers. Conclusions: In Korean men, smoking-related cancer mortality rates have decreased. Our findings also indicate that current decreases in smoking-related cancer mortality rates have mainly been due to a decrease in the birth cohort effect, which suggest that decrease in smoking rates.

  3. The Impact of Occupational Safety and Health Regulation, 1973-1983

    OpenAIRE

    W. Kip Viscusi

    1986-01-01

    Using a sample of manufacturing industries from 1973 to 1983, this article reexamines OSHA's impact on workplace safety. Evidence supporting OSHA's effectiveness is stronger than that presented in most previous studies but remains quite mixed. Only for the incidence of lost workday injuries and illnesses is there evidence of a statistically significant OSHA impact for an equation that is stable over the 1973-1983 period. The magnitude of the effect is modest, and the effect is not robust with...

  4. Correlates of self-reported pelvic inflammatory disease treatment in sexually experienced reproductive-aged women in the United States, 1995 and 2006-2010.

    Science.gov (United States)

    Leichliter, Jami S; Chandra, Anjani; Aral, Sevgi O

    2013-05-01

    Few studies have examined recent temporal trends in self-reported receipt of pelvic inflammatory disease (PID) treatment. We assessed trends in receipt of PID treatment and associated correlates using national survey data. We used data from the National Survey of Family Growth, a multistage national probability survey of 15- to 44-year-old women. We examined trends in self-reported receipt of PID treatment from 1995, 2002, to 2006-2010. In addition, we examined correlates of PID treatment in 1995 and 2006-2010 in bivariate and adjusted analyses. From 1995 to 2002, receipt of PID treatment significantly declined from 8.6% to 5.7% (P < 0.0001); however, there was no difference from 2002 to 2006-2010 (5.0%, P = 0.16). In bivariate analyses, racial differences in PID treatment declined across time; in 2006-2010, there was no significant difference between racial/ethnic groups (P = 0.22). Also in bivariate analyses, similar to 1995, in 2006 to 2010, some of the highest reports of receipt of PID treatment were women who were 35 to 44 years old (5.6%), had an income less than 150% of poverty level (7.5%), had less than high school education (6.7%), douched (7.7%), had intercourse before age 15 years (10.3%), and had 10 or more lifetime partners (8.0%). In adjusted analyses, differing from 1995, women at less than 150% of the poverty level were more likely (adjusted odds ratio [AOR], 2.60; 95% confidence interval [CI], 1.79-3.76) than women at 300% or more of the poverty level to have received PID treatment in 2006-2010. Receipt of PID treatment declined from 1995 to 2006-2010, with the burden affecting women of lower socioeconomic status.

  5. Endometrial Cancer Trends by Race and Histology in the USA: Projecting the Number of New Cases from 2015 to 2040.

    Science.gov (United States)

    Gaber, Charles; Meza, Rafael; Ruterbusch, Julie J; Cote, Michele L

    2016-10-17

    The aim of this study is to explore incidence and incidence-based mortality trends for endometrial cancer in the USA and project future incident cases, accounting for differences by race and histological subtype. Data on age-adjusted and age-specific incidence and mortality rates of endometrial cancer were obtained from the Surveillance, Epidemiology, and End Results 18 registries. Trends in rates were analyzed using Joinpoint regression, and average annual percent change (AAPC) in recent years (2006-2011) was computed for histological subtypes by race. Age, histological, and race-specific rates were applied to US Census Bureau population census estimates to project new cases from 2015 to 2040, accounting for observed AAPC trends, which were progressively attenuated for the future years. The annual number of cases is projected to increase substantially from 2015 to 2040 across all racial groups. Considerable variation in incidence and mortality trends was observed both between and within racial groups when considering histology. As the US population undergoes demographic changes, incidence of endometrial cancer is projected to rise. The increase will occur in all racial groups, but larger increases will be seen in aggressive histology subtypes that disproportionately affect black women.

  6. Disparities of time trends and birth cohort effects on invasive breast cancer incidence in Shanghai and Hong Kong pre- and post-menopausal women.

    Science.gov (United States)

    Wang, Feng; Tse, Lap Ah; Chan, Wing-Cheong; Kwok, Carol Chi-Hei; Leung, Siu-Lan; Wu, Cherry; Mang, Oscar Wai-Kong; Ngan, Roger Kai-Cheong; Li, Mengjie; Yu, Wai-Cho; Tsang, Koon-Ho; Law, Sze-Hong; Miao, Xiaoping; Wu, Chunxiao; Zheng, Ying; Wu, Fan; Yang, Xiaohong R; Yu, Ignatius Tak-Sun

    2017-05-23

    Breast cancer is the leading cause of cancer morbidity among Shanghai and Hong Kong women, which contributes to 20-25% of new female cancer incidents. This study aimed to describe the temporal trend of breast cancer and interpret the potential effects on the observed secular trends. Cancer incident data were obtained from the cancer registries. Age-standardized incidence rate was computed by the direct method using the World population of 2000. Average annual percentage change (AAPC) in incidence rate was estimated by the Joinpoint regression. Age, period and cohort effects were assessed by using a log-linear model with Poisson regression. During 1976-2009, an increasing trend of breast cancer incidence was observed, with an AAPC of 1.73 [95% confidence interval (CI): 1.54-1.92)] for women in Hong Kong and 2.83 (95% CI, 2.26-3.40) in Shanghai. Greater upward trends were revealed in Shanghai women aged 50 years old or above (AAPC = 3.09; 95% CI, 1.48-4.73). Using age at 50 years old as cut-point, strong birth cohort effects were shown in both pre- and post-menopausal women, though a more remarkable effect was suggested in Shanghai post-menopausal women. No evidence for a period effect was indicated. Incidence rate of breast cancer has been more speedy in Shanghai post-menopausal women than that of the Hong Kong women over the past 30 years. Decreased birth rate and increasing environmental exposures (e.g., light-at-night) over successive generations may have constituted major impacts on the birth cohort effects, especially for the post-menopausal breast cancer; further analytic studies are warranted.

  7. Trends in glaucoma surgery incidence and reimbursement for physician services in the Medicare population from 1995 to 1998.

    Science.gov (United States)

    Paikal, David; Yu, Fei; Coleman, Anne L

    2002-07-01

    To better understand the relationship between glaucoma management and economic incentives, we examined the volume and the reimbursement of argon laser trabeculoplasty (ALT) and trabeculectomy in a 5% random sample of the Medicare population from 1995 to 1998. Retrospective cohort study. Subjects in a 5% random sample of the Medicare population who had ALT and trabeculectomy from 1995 to 1998. Using the Health Care Financing Administration (HCFA) Physician/Supplier Part-B files for a 5% random sample of the Medicare population, we identified all subjects who had ALT and trabeculectomy from 1995 to 1998. Descriptive summaries (the number of surgeries and the mean and the standard deviation of reimbursement per surgery) were calculated for each year. Analysis of variance was used to test for differences in reimbursement per surgery across years. Chi-square tests were used to assess any associations between the changing numbers of ALTs and trabeculectomies over the study period and both age and race. We assessed the number of ALTs and trabeculectomies and the allowed charges for each surgery in the 5% random sample of the Medicare population from 1995 to 1998. The volume of both ALTs and trabeculectomies declined during the study period. Reimbursement per surgery for both ALT and trabeculectomy varied significantly across years (P management of glaucoma, among other factors.

  8. Differences between Men and Women in Time Trends in Lung Cancer Mortality in Spain (1980-2013).

    Science.gov (United States)

    Martín-Sánchez, Juan Carlos; Clèries, Ramon; Lidón-Moyano, Cristina; González-de Paz, Luis; Martínez-Sánchez, Jose M

    2016-06-01

    The main risk factor for lung cancer is smoking, a habit that varies according to age and sex. The objective of this study was to explore trends in lung cancer mortality by sex and age from 1980 to 2013 in Spain. We used lung cancer mortality (International Classification of Diseases code 162 for the 9th edition, and codes C33 and C34 for 10th edition) and population data from the Spanish National Statistics Institute. Crude, truncated, age-adjusted mortality and age-specific mortality rates were assessed through joinpoint regression to estimate the annual percent change (APC). Age-adjusted mortality rate significantly increased from 1980 to 1991 among men (APC=3.12%) and significantly decreased between 2001 and 2013 (APC=-1.53%), a similar pattern was observed in age-specific rates. Among women, age-adjusted mortality rate increased from 1989 (APC 1989-1997=1.82%), with the greatest increase observed from 1997 until the end of the study in 2013 (APC=4.41%). Diverging trends in the prevalence of smoking could explain the increase in the rate of lung cancer-related mortality among Spanish women since the early 1990s. Public health policies should be implemented to reduce tobacco consumption in women and halt the increase in lung cancer mortality. Copyright © 2016 SEPAR. Published by Elsevier Espana. All rights reserved.

  9. Contraceptive sterilization among Canadians, 1984-1995

    Directory of Open Access Journals (Sweden)

    Krishnan, Vijaya

    2004-01-01

    Full Text Available EnglishPrior to early 1970s, traditional methods were the principal means ofcontrolling the number and spacing of births. Today, an estimated 57 per cent of the world's marriedwomen use contraceptives and half use modern methods such as medical sterilizations. Recent statisticssuggest that Canada has the highest sterilization rate in the Western world. This paper presentsfindings of research examining sterilization trends in Canada with respect to changing patterns in theuse of modern contraceptives, using data from the 1984 Canadian Fertility Survey (CFS and the 1995General Social Survey (GSS. The main finding is that there is a decrease in the use of tubal ligationand an increase in the use of hysterectomy over the period 1984-1995. Less educated women are morelikely to be in the forefront of modern methdos of contraception.FrenchAvant les années 1970, les méthodes traditionnelles représentaient le principalmoyen de contrôler et d’espacer le nombre de naissances. De nos jours, onestime que 57 pour cent des femmes mariées dans le monde entier utilisent unmoyen contraceptif et la moitié utilise des méthodes modernes telles que lastérilisation. Les dernières statistiques indiquent que le Canada compte le tauxde stérilisations le plus élevé dans le monde occidental. Cet article présente lesconclusions de recherches portant sur les tendances en matière de stérilisation auCanada en ce qui concerne les modèles changeants d’utilisation de moyens decontraception modernes et ce, à partir de données de l’Enquête canadienne sur lafécondité de 1984 et de l’Enquête sociale générale (ESG de 1995. La principaleconclusion qui en est ressortie est une réduction de la ligature des trompes etune augmentation du nombre d’hystérectomies de 1984 à 1995. Les femmesmoins éduquées sont plus portées à se trouver au premier plan des méthodes decontraception modernes.

  10. The Janus serum bank and biomarkers of cancer

    Directory of Open Access Journals (Sweden)

    Randi Gislefoss

    2009-10-01

    Full Text Available The Janus serum bank, established in 1973, contains sera stored at –25 degrees collected from 330,000 originally healthy individuals. The number of cancer cases have increased from zero in 1973 to more than 50,000 in 2005, including invasive and non-invasive cancers. Information on cases have been obtained by coupling the Janus file against the Norwegian Cancer Registry. The sera have been used in over 70 different cancers research projects, usually in case-control studies and in collaboration with national and international research groups. The type of biomarker analysed include antibodies against Chlamydia, CMV, Epstein Barr virus, HPV and Helicobacter pylori. Leptin, long chain fatty acids, androgens and other hormones, vitamins as well as environmental toxins such as organochlorines are other types of cancer biomarkers investigated. Mutation analyses (BRCA-1 etc have been possible using PCR and the trace amounts of DNA remaining in the sera.Janus serum bank ble etablert i 1973 og inneholder sera lagret ved –25 grader, innsamlet fra 330.000 opprinnelig friske personer. Antall krefttilfeller har steget fra null i 1973 til over 50.000 i år 2005, inkludert både invasiv og ikke-invasiv kreft. Informasjon om kasus er tilgjengelig ved å koble Janus-filene mot Kreftregisterets databaser. Serumprøvene er blitt benyttet i over 70 forskjellige kreftforskningsprosjekter, som oftest i kasus-kontroll studier og i samarbeide med en rekke nasjonale og internasjonale forskningsgrupper. Mange ulike biomarkører på kreft er blitt analysert, bl.a. antistoffer mot Chlamydia, CMV, Epstein Barr virus, HPV og Helicobacter pylori. Leptin, lange fettsyrer, androgener og andre hormoner, vitaminer såvel som miljøgifter av typen organiske klorforbindelser er eksempler på andre kreftbiomarkører som er undersøkt. Det har også vært mulig å gjøre mutasjonsanalyser (BRCA-1 etc ved å bruke PCR til å amplifisere opp den spormengden DNA som finnes i serum.

  11. Stage-specific incidence rates and trends of prostate cancer by age, race, and ethnicity, United States, 2004-2014.

    Science.gov (United States)

    Li, Jun; Siegel, David A; King, Jessica B

    2018-05-01

    Current literature shows different findings on the contemporary trends of distant-stage prostate cancer incidence, in part, due to low study population coverage and wide age groupings. This study aimed to examine the stage-specific incidence rates and trends of prostate cancer by age (5-year grouping), race, and ethnicity using nationwide cancer registry data. Data on prostate cancer cases came from the 2004-2014 United States Cancer Statistics data set. We calculated stage-specific incidence and 95% confidence intervals by age (5-year age grouping), race, and ethnicity. To measure the changes in rates over time, we calculated annual percentage change (APC). We identified 2,137,054 incident prostate cancers diagnosed during 2004-2014, with an age-adjusted incidence rate of 453.8 per 100,000. Distant-stage prostate cancer incidence significantly decreased during 2004-2010 (APC = -1.2) and increased during 2010-2014 (APC = 3.3). Significant increases in distant prostate cancer incidence also occurred in men aged older than or equal to 50 years except men aged 65-74 and older than or equal to 85 years, in men with white race (APC = 3.9), and non-Hispanic ethnicity (APC = 3.5). Using data representing over 99% of U.S. population, we found that incidence rates of distant-stage prostate cancer significantly increased during 2010-2014 among men in certain ages, in white, and with non-Hispanic ethnicity. Published by Elsevier Inc.

  12. Incidence, Trends and Ethnic Differences of Oropharyngeal, Anal and Cervical Cancers: Singapore, 1968-2012

    Science.gov (United States)

    Lam, Jennifer O.; Lim, Wei-Yen; Chow, Khuan-Yew; D’Souza, Gypsyamber

    2015-01-01

    In recent decades, several Western countries have reported an increase in oropharyngeal and anal cancers caused by human papillomavirus (HPV). Trends in HPV-associated cancers in Asia have not been as well described. We describe the epidemiology of potentially HPV-related cancers reported to the Singapore Cancer Registry from 1968–2012. Analysis included 998 oropharyngeal squamous cell carcinoma (OPSCC), 183 anal squamous cell carcinoma (ASCC) and 8,019 invasive cervical cancer (ICC) cases. Additionally, 368 anal non-squamous cell carcinoma (ANSCC) and 2,018 non-oropharyngeal head and neck carcinoma (non-OP HNC) cases were included as comparators. Age-standardized incidence rates (ASR) were determined by gender and ethnicity (Chinese, Malay and Indian). Joinpoint regression was used to evaluate annual percentage change (APC) in incidence. OPSCC incidence increased in both genders (men 1993–2012, APC = 1.9%, pSingapore, but Pap screening programs have led to consistently decreasing incidence. PMID:26720001

  13. Incidence and mortality of lung cancer: global trends and association with socioeconomic status.

    Science.gov (United States)

    Wong, Martin C S; Lao, Xiang Qian; Ho, Kin-Fai; Goggins, William B; Tse, Shelly L A

    2017-10-30

    We examined the correlation between lung cancer incidence/mortality and country-specific socioeconomic development, and evaluated its most recent global trends. We retrieved its age-standardized incidence rates from the GLOBOCAN database, and temporal patterns were assessed from global databases. We employed simple linear regression analysis to evaluate their correlations with Human Development Index (HDI) and Gross Domestic Product (GDP) per capita. The average annual percent changes (AAPC) of the trends were evaluated from join-point regression analysis. Country-specific HDI was strongly correlated with age-standardized incidence (r = 0.70) and mortality (r = 0.67), and to a lesser extent GDP (r = 0.24 to 0.55). Among men, 22 and 30 (out of 38 and 36) countries showed declining incidence and mortality trends, respectively; whilst among women, 19 and 16 countries showed increasing incidence and mortality trends, respectively. Among men, the AAPCs ranged from -2.8 to -0.6 (incidence) and -3.6 to -1.1 (mortality) in countries with declining trend, whereas among women the AAPC range was 0.4 to 8.9 (incidence) and 1 to 4.4 (mortality) in countries with increasing trend. Among women, Brazil, Spain and Cyprus had the greatest incidence increase, and all countries in Western, Southern and Eastern Europe reported increasing mortality. These findings highlighted the need for targeted preventive measures.

  14. Scientific publications 1973-1974

    International Nuclear Information System (INIS)

    1976-01-01

    This catalogue supplements the HMI report 'Scientific publications 1958-1972' (HMI-B-142). It lists all the publications by the Hahn-Meitner-Institut fuer Kernforschung Berlin of the years 1973-1974. The catalogue contains progress reports, dissertations, publications from scientific journals and anthologies if these are available in print. The titles listed in this catalogue are based on the HMI's annual reports. The classification according to fields and departments follows the development of the institute as outlined in the annual reports. Further classification is done according to the year of publication. (orig./HK) [de

  15. Prostate cancer in Denmark 1978-2009 - trends in incidence and mortality

    DEFF Research Database (Denmark)

    Outzen, Malene; Brasso, Klaus; Martinussen, Nick

    2013-01-01

    with localised disease. Conclusion. The observed increase in PC incidence during the period 1993-2009 in Denmark may be attributed primarily to increasing unsystematic use of prostate specific antigen (PSA) testing. The mortality rates remained stable during the same period suggesting that there is not yet any......Abstract Background. The incidence of prostate cancer (PC) has increased during the last 15 years in Denmark, whereas the mortality has remained largely unchanged. This register study aimed to investigate the trends in PC incidence and mortality in Denmark 1978-2009 with special focus on the recent......-year calendar periods (1978-2007) and a two-year calendar period (2008-2009). Trends in incidence rates were estimated for specific age groups, birth cohorts, and clinical stage. Results. The age-standardised incidence rate of PC increased from 29.2 per 100 000 person-years in 1978-1982 to 76.2 per 100 000...

  16. Effects of Helicobacter pylori infection and smoking on gastric cancer incidence in China: a population-level analysis of trends and projections

    Science.gov (United States)

    Goldie, Sue J.; Kuntz, Karen M.; Ezzati, Majid

    2010-01-01

    Objective Although gastric cancer incidence is declining in China, trends may differ from historical patterns in developed countries. Our aim was to (1) retrospectively estimate the effects of Helicobacter pylori (H. pylori) and smoking on past gastric cancer incidence and (2) project how interventions on these two risk factors can reduce future incidence. Methods We used a population-based model of intestinal-type gastric cancer to estimate gastric cancer incidence between 1985 and 2050. Disease and risk factor data in the model were from community-based epidemiological studies and national prevalence surveys. Results Between 1985 and 2005, age-standardized gastric cancer incidence among Chinese men declined from 30.8 to 27.2 per 100,000 (12%); trends in H. pylori and smoking prevalences accounted for >30% of overall decline. If past risk factor trends continue, gastric cancer incidence will decline an additional 30% by 2050. Yet, annual cases will increase from 116,000 to 201,000 due to population growth and aging. Assuming that H. pylori prevention/treatment and tobacco control are implemented in 2010, the decline in gastric cancer incidence is projected to increase to 33% with universal H. pylori treatment for 20-year-olds, 42% for a hypothetical childhood H. pylori vaccine, and 34% for aggressive tobacco control. Conclusions The decline in gastric cancer incidence has been slower than in developed countries and will be offset by population growth and aging. Public health interventions should be implemented to reduce the total number of cases. PMID:19642005

  17. World oil prices: Up or down in 1995? and beyond?

    International Nuclear Information System (INIS)

    Browning, R.E.

    1994-01-01

    After a brief review of historical oil prices up to 1993-94, the factors influencing future prices are discussed. A survey of oil supply and demand over 1986-1993 shows oil demand has risen in Asia and fallen in the former Soviet Union and central/eastern Europe (FSU/CEE). Non-OPEC oil supply fell from 42.1 million bbl/d (MMBD) in 1986 to 40.6 MMBD in 1993, reflecting declines in Russian and U.S. production. Total OPEC production rose in the same period from 18.3 MMBD to 24.7 MMBD. OPEC production will continue to be dominant in determining prices, and demand in growing Asian economies and the FSU/CEE countries will be the most important and uncertain demand-side factor. If 7.5 MMBD of new OPEC capacity comes on stream by 2000 and OPEC production averages 31 MMBD in 2000, the utilization rate for OPEC oil at that time would be about the same as in 1973-79 and 1994. World oil production costs vary considerably by region, with the USA, North Sea, and Canada having relatively high costs; yet even in those regions, costs have been declining. A global weighted average cost based on 1993 production is $8-9/bbl. Fiscal and financial factors affecting oil prices include the need for oil revenue among oil producers. This need will put pressure on FSU economies to continue exports, although increases in such exports will require new infrastructure. In any case, the world oil market is likely to see a continuing trend to regarding oil as a commodity, which tends to reduce the control that physical participants exert on price-setting. Long-term real prices are not expected to rise but will likely remain volatile, cycling around $13/bbl. Spot prices in 1995 for West Texas Intermediate are forecast to be in the $16-20/bbl range. 4 figs., 4 tabs

  18. 1973 : Trudeau tangles with Alberta

    International Nuclear Information System (INIS)

    Anon.

    2008-01-01

    In 1973, the Canadian government took measures to place oil exports under federal control and placed a freeze on oil prices. Prime Minister Pierre Trudeau unveiled plans for a national energy policy that would dissolve the Borden policy which prevented western Canadian crude from accessing the Montreal refining market. Trudeau's policy would extend the oil price freeze and created a one-price national market for Canadian oil. Plans were also underway to create a national oil company that would stimulate exploration and exploitation of new energy resources. The Premier of Alberta was also implementing energy regulations at the same time, aimed at consolidating control of Alberta's own resources within the framework of the Constitution and preventing Ottawa from gaining full control of all of Alberta's energy resources. Other key events in 1973 were the introduction of Saskatchewan's Oil and Gas Conservation, Stabilization and Development Act which gave the province the right to take over the oil rights of all private companies in producing areas. The Polar Gas Project was created to conduct research into building a gas pipeline from the Arctic Islands, and a Canadian Arctic gas study revealed that the Mackenzie Pipeline could be delivering gas by 1977. 1 tab., 1 fig

  19. Long-Term Trends in Hematological and Nutritional Status After Gastrectomy for Gastric Cancer.

    Science.gov (United States)

    Kim, Ji-Hyun; Bae, You-Jin; Jun, Kyong-Hwa; Chin, Hyung-Min

    2017-08-01

    This study investigated long-term trends in hematological and nutritional parameters after gastrectomy for gastric cancer and evaluated the influence of the reconstruction type on these trends. The medical records of 558 patients who underwent curative gastrectomy with standard lymph node dissection for stage I gastric cancer between January 2006 and December 2013 were reviewed. The hematological and nutritional parameters evaluated included hemoglobin, ferritin, vitamin B 12 , total protein, albumin, total cholesterol, triglyceride, and calcium. The patients were followed up for 6 months postoperatively and then annually until death, cancer recurrence, or follow-up loss. In the long term, ferritin and triglyceride gradually decreased after gastrectomy, while the other parameters decreased slightly or were stable. In the comparisons according to reconstruction type, the Roux-en-Y group had the lowest levels of hemoglobin, ferritin, vitamin B12, total protein, albumin, and total cholesterol beginning 6 months postoperatively compared with the Billroth I and II groups. However, only ferritin and vitamin B 12 had significant differences in the 5-year cumulative incidences of deficiency/reduction according to the reconstruction type, whereas albumin, triglyceride, total cholesterol, and calcium did not. Although malabsorption and malnutrition are common in patients after a gastrectomy, most nutritional parameters were stable or decreased slightly in the long-term and were not markedly influenced by the reconstruction type or extent of gastrectomy. Therefore, for more accurate nutritional assessment after gastrectomy, multidirectional monitoring should be considered rather than simply measuring biochemical parameters.

  20. Land-Cover Change in the East Central Texas Plains, 1973-2000

    Science.gov (United States)

    Karstensen, Krista A.

    2009-01-01

    Project Background: The Geographic Analysis and Monitoring (GAM) Program of the U.S. Geological Survey (USGS) Land Cover Trends project is focused on understanding the rates, trends, causes, and consequences of contemporary U.S. land-use and land-cover change. The objectives of the study are to: (1) develop a comprehensive methodology for using sampling and change analysis techniques and Landsat Multispectral Scanner (MSS) and Thematic Mapper (TM) data for measuring regional land-cover change across the United States, (2) characterize the types, rates and temporal variability of change for a 30-year period, (3) document regional driving forces and consequences of change, and (4) prepare a national synthesis of land-cover change (Loveland and others, 1999). Using the 1999 Environmental Protection Agency (EPA) Level III ecoregions derived from Omernik (1987) as the geographic framework, geospatial data collected between 1973 and 2000 were processed and analyzed to characterize ecosystem responses to land-use changes. The 27-year study period was divided into five temporal periods: 1973-1980, 1980-1986, 1986-1992, 1992-2000, and 1973-2000. General land-cover classes such as water, developed, grassland/shrubland, and agriculture for these periods were interpreted from Landsat MSS, TM, and Enhanced Thematic Mapper Plus imagery to categorize land-cover change and evaluate using a modified Anderson Land-Use Land-Cover Classification System for image interpretation. The interpretation of these land-cover classes complement the program objective of looking at land-use change with cover serving as a surrogate for land use. The land-cover change rates are estimated using a stratified, random sampling of 10-kilometer (km) by 10-km blocks allocated within each ecoregion. For each sample block, satellite images are used to interpret land-cover change for the five time periods previously mentioned. Additionally, historical aerial photographs from similar timeframes and other

  1. Analysis of 10-year cause-specific mortality of patients with breast cancer treated in New South Wales in 1995

    International Nuclear Information System (INIS)

    Wang, Wei; Stuart, Kirsty; Boyages, John; O'Connell, Dianne

    2011-01-01

    The objective of this study is to assess cause-specific mortality for patients with breast cancer and to determine if excess cardiac death was associated with radiation therapy (RT). We obtained 10-year cause-specific mortality information from the New South Wales (NSW) Central Cancer Registry and National Death Index on 1242 patients with unilateral stage I–III invasive breast cancer in NSW, Australia, diagnosed over a 6-month period in 1995. We compared actuarial cause-specific mortality (breast cancer, cardiac, other cancers and other causes) for patients who received left-sided, right-sided or no RT. Mortality due to breast cancer or due to other cancers was not significantly different (P = 0.30 and P = 0.11) between the three subgroups. Mortality due to cardiac and other causes was higher in patients who did not have radiotherapy (P = 0.001 and P < 0.001). A total of 52 cardiac deaths in 1242 patients (4.2%) occurred – six of 274 patients (2.2%) in the left-sided radiotherapy group, four of 245 patients (1.6%) in the right-sided radiotherapy group (P = 0.63) and 42 of 723 patients (5.8%) in the no radiotherapy group. Most cardiac deaths (46 of 52 cases) occurred in patients aged 70 years or older at the time of diagnosis. There were no differences in cardiac mortality between the three treatment groups for those aged 70 years or older (P = 0.22, log-rank test), suggesting that the higher overall cardiac mortality rate in the no-RT group is due to a higher percentage of patients aged 70 years or older. Of the 10 patients who died from cardiac causes and who had received RT, none had received chemotherapy or irradiation to the internal mammary chain. There is no excess cardiac mortality due to RT within the first decade in a population series of patients with breast cancer treated with modern radiotherapy.

  2. Ethnic differences in the time trend of female breast cancer incidence: Singapore, 1968 – 2002

    Directory of Open Access Journals (Sweden)

    Tan Chuen-Seng

    2006-11-01

    Full Text Available Abstract Background From 1968 to 2002, Singapore experienced an almost three-fold increase in breast cancer incidence. This increase appeared to be different across the three main ethnic groups: Chinese, Malays and Indians. This paper used age-period-cohort (APC modelling, to determine the effects of age at diagnosis, calendar period, and birth cohort on breast cancer incidence for each ethnic group. Methods This study included all breast cancer cases (n = 15,269 in the three ethnic groups, reported to the Singapore Cancer Registry from 1968 to 2002 between the ages 25 to 79. Age-specific fertility rates from the Department of Statistics were used to explore the role of fertility. Results In the 1970s, Indian women had the highest age-standardized breast cancer but by the mid-1980s the highest rates were seen among the Chinese. Remarkable differences were seen in the age-specific incidence rates by ethnic groups. After age 49, the incidence rates for the Chinese and Malays leveled off whereas it continued to rise in the Indians. While our analyses provided some evidence that an age-drift model described the trend seen in the Indians, age-period-cohort model and age-cohort model had the best fit for the Chinese and Malays aged 25 to 79 respectively. Overall, Chinese and Malay women born in later cohorts were at increased risk of developing breast cancer relative to their counterparts in the earlier cohorts. The three ethnic groups experienced similar changes in their fertility in the 1970s, which likely explained much of the increase in their breast cancer incidence but not the ethnic differences. There was a stronger inverse association between total fertility rate and pre-menopausal breast cancer incidence in the Chinese and Malays than the Indians. Conclusion The observed dissimilarity among ethnic groups suggests ethnic differences in exposure or response to certain risk factors. It is likely that longer and subtler differences in

  3. Increasing trends of sleep complaints in the city of Sao Paulo, Brazil.

    Science.gov (United States)

    Santos-Silva, Rogerio; Bittencourt, Lia Rita Azeredo; Pires, Maria Laura Nogueira; de Mello, Marco Tulio; Taddei, Jose Augusto; Benedito-Silva, Ana Amelia; Pompeia, Celine; Tufik, Sergio

    2010-06-01

    The aim of this study was to compare the prevalence of sleep habits and complaints and to estimate the secular trends through three population-based surveys carried out in 1987, 1995, and 2007 in the general adult population of the city of Sao Paulo, Brazil. Surveys were performed using the same three-stage cluster-sampling technique in three consecutive decades to obtain representative samples of the inhabitants of Sao Paulo with respect to gender, age (20-80 years), and socio-economic status. Sample sizes were 1000 volunteers in 1987 and 1995 surveys and 1101 in a 2007 survey. In each survey, the UNIFESP Sleep Questionnaire was administered face-to-face in each household selected. For 1987, 1995, and 2007, respectively, difficulty initiating sleep (weighted frequency %; 95% CI) [(13.9; 11.9-16.2), (19.15; 16.8-21.6), and (25.0; 22.5-27.8)], difficulty maintaining sleep [(15.8; 13.7-18.2), (27.6; 24.9-30.4), and (36.5; 33.5-39.5)], and early morning awakening [(10.6; 8.8-12.7), (14.2; 12.2-16.5), and (26.7; 24-29.6)] increased in the general population over time, mostly in women. Habitual snoring was the most commonly reported complaint across decades and was more prevalent in men. There was no statistically significant difference in snoring complaints between 1987 (21.5; 19.1-24.2) and 1995 (19.0; 16.7-21.6), but a significant increase was noted in 2007 (41.7; 38.6-44.8). Nightmares, bruxism, leg cramps, and somnambulism complaints were significantly higher in 2007 compared to 1987 and 1995. All were more frequent in women. This is the first study comparing sleep complaints in probabilistic population-based samples from the same metropolitan area, using the same methodology across three consecutive decades. Clear trends of increasing sleep complaints were observed, which increased faster between 1995 and 2007 than from 1987 to 1995. These secular trends should be considered a relevant public health issue and support the need for development of health care and

  4. Basic Survey Small-scale Natural Gas Consumption (BAK 1995)

    International Nuclear Information System (INIS)

    Bos, R.E.J.; Weegink, R.J.

    1996-01-01

    The annual title survey shows for 1995 that Dutch households consumed more than 120 million m 3 of natural gas, which is higher than in 1994. The average consumption per dwelling slightly decreased. Gas consumption for cooking and hot water remained the same. The slight decrease in the average consumption is caused by space heating. The decrease seemed to halt last year, but still continues for the time being. However, it is too early to refer to it as a trend. 3 figs., 7 tabs

  5. Land-cover change in the Ozark Highlands, 1973-2000

    Science.gov (United States)

    Karstensen, Krista A.

    2010-01-01

    Led by the Geographic Analysis and Monitoring Program of the U.S. Geological Survey (USGS) in collaboration with the U.S. Environmental Protection Agency (EPA) and the National Aeronautics and Space Administration (NASA), the Land-Cover Trends Project was initiated in 1999 and aims to document the types, geographic distributions, and rates of land-cover change on a region by region basis for the conterminous United States, and to determine some of the key drivers and consequences of the change (Loveland and others, 2002). For 1973, 1980, 1986, 1992, and 2000 land-cover maps derived from the Landsat series are classified by visual interpretation, inspection of historical aerial photography and ground survey, into 11 land-cover classes. The classes are defined to capture land cover that is discernable in Landsat data. A stratified probability-based sampling methodology undertaken within the 84 Omernik Level III Ecoregions (Omernik, 1987) was used to locate the blocks, with 9 to 48 blocks per ecoregion. The sampling was designed to enable a statistically robust 'scaling up' of the sample-classification data to estimate areal land-cover change within each ecoregion (Loveland and others, 2002; Stehman and others, 2005). At the time of writing, approximately 90 percent of the 84 conterminous United States ecoregions have been processed by the Land-Cover Trends Project. Results from these completed ecoregions illustrate that across the conterminous United States there is no single profile of land-cover/land-use change, rather, there are varying pulses affected by clusters of change agents (Loveland and others, 2002). Land-Cover Trends Project results for the conterminous United States to-date are being used for collaborative environmental change research with partners such as; the National Science Foundation, the National Oceanic and Atmospheric Administration, and the U.S. Fish and Wildlife Service. The strategy has also been adapted for use in a NASA global

  6. Do gender-based disparities in authorship also exist in cancer palliative care? A 15-year survey of the cancer palliative care literature.

    Science.gov (United States)

    Singh, Preet Paul; Jatoi, Aminah

    2008-01-01

    Women physicians in the United States publish less than men and advance academically at a slower pace. Do such gender-based disparities also occur in cancer palliative care, a field in which women appear to hold a strong interest? We undertook a detailed survey of the cancer palliative care literature. We selected 5 cancer palliative care journals on the basis of their high impact factors, and we assessed authorship for the years 1990, 1995, 2000, and 2005. We determined gender and highest educational degree for all US first and last authors. A total of 794 authors are the focus of this report. In 2005, 50% of first authors were women, but only 14% were women physicians. Similarly, 39% of senior authors were women during this year, but only 8% were women physicians. Over this 15-year period, no statistically significant trends were detected to indicate an increase in the number of women authors. These findings are sobering. Future efforts might focus on strategies to improve rates of authorship and, ultimately, improve rates of academic promotion for women interested in cancer palliative care.

  7. Trends in breast cancer incidence among women with type-2 diabetes in British general practice

    DEFF Research Database (Denmark)

    Bronsveld, Heleen K; Peeters, Paul J H L; de Groot, Mark C H

    2017-01-01

    Aims: To quantify breast cancer incidence in women with type-2 diabetes and assess age-standardized trends in invasive breast cancer incidence over time and by age groups. Methods: A population-based cohort study was conducted using the British general practice database (Clinical Practice Research...... Datalink) using data from 1989 to 2012. All adult women prescribed anti-hyperglycemic medication were selected and matched (1:1) on age and clinical practice to a reference cohort without diabetes. Results: During approximately 1.6 million person years (py), 2371 breast cancer cases were diagnosed...... that observed in the reference cohort (148, 95%CI:141-156); with an incidence rate ratio (IRR) of 1.01 (95%CI:0.94-1.08, p. >. 0.05). Conclusions: Currently, around 2880 women with type-2 diabetes are diagnosed with breast cancer per year in the United Kingdom. However, breast cancer incidence remained stable...

  8. Dietary fiber and whole-grain consumption in relation to colorectal cancer in the NIH-AARP Diet and Health Study.

    Science.gov (United States)

    Schatzkin, Arthur; Mouw, Traci; Park, Yikyung; Subar, Amy F; Kipnis, Victor; Hollenbeck, Albert; Leitzmann, Michael F; Thompson, Frances E

    2007-05-01

    Whether the intake of dietary fiber can protect against colorectal cancer is a long-standing question of considerable public health import, but the epidemiologic evidence has been inconsistent. The objective was to investigate the relation between dietary fiber and whole-grain food intakes and invasive colorectal cancer in the prospective National Institutes of Health-AARP Diet and Health Study. The analytic cohort consisted of 291 988 men and 197 623 women aged 50-71 y. Diet was assessed with a self-administered food-frequency questionnaire at baseline in 1995-1996; 2974 incident colorectal cancer cases were identified during 5 y of follow-up. The Cox proportional hazards model was used to estimate the relative risks (RRs) and 95% CIs. Total dietary fiber intake was not associated with colorectal cancer. The multivariate RR for the highest compared with the lowest intake quintile (RR(Q5-Q1)) was 0.99 (95% CI: 0.85, 1.15; P for trend = 0.96). In analyses of fiber from different food sources, only fiber from grains was associated with a lower risk of colorectal cancer (multivariate RR(Q5-Q1): 0.86; 95% CI: 0.76, 0.98; P for trend = 0.01). Whole-grain intake was inversely associated with colorectal cancer risk: the multivariate RR(Q5-Q1) was 0.79 (95% CI: 0.70, 0.89) for the whole cohort (P for trend cancer. In this large prospective cohort study, total dietary fiber intake was not associated with colorectal cancer risk, whereas whole-grain consumption was associated with a modest reduced risk.

  9. Rising trends of gastric cancer and peptic ulcer in the 19th century.

    Science.gov (United States)

    Sonnenberg, A; Baron, J H

    2010-10-01

    The risk of dying from gastric cancer appears to have increased among consecutive generations born during the 19th century. To follow the time trends of hospitalization for gastric cancer and test whether they confirm such increase. Inpatient records of the last two centuries from four hospitals in Scotland and three US hospitals were analysed. Proportional rates of hospitalization for gastric cancer, gastric ulcer and duodenal ulcer were calculated during consecutive 5-year periods. The data from all seven cities revealed strikingly similar patterns. No hospital admissions for gastric cancer or peptic ulcer were recorded prior to 1800. Hospital admissions for gastric cancer increased in an exponential fashion throughout the 19th and the beginning of the 20th century. In a majority of cities, the rise in hospitalization for gastric cancer preceded a similar rise in hospitalization for gastric ulcer. Hospitalization for these two latter diagnoses clearly preceded hospitalization for duodenal ulcer by 20-40 years. The occurrence of gastric cancer, gastric ulcer and duodenal ulcer markedly increased during the 19th century. Improvements in hygiene may have resulted in the decline of infections by other gastrointestinal organisms that had previously kept concomitant infection by Helicobacter pylori suppressed. Published 2010. This article is a US Government work and is in the public domain in the USA.

  10. Trends in kidney cancer among the elderly in Denmark, 1980-2012.

    Science.gov (United States)

    Azawi, Nessn H; Joergensen, Simon Moeller; Jensen, Niels Viggo; Clark, Peter E; Lund, Lars

    2016-01-01

    The purpose of this study is to elucidate incidence, mortality, survival, and prevalence of kidney cancer in elderly persons compared with younger persons in Denmark. Cancer of the kidney was defined as ICD-10 code DC 64. Data derived from the NORDCAN database with comparable data on cancer incidence, mortality, prevalence and relative survival in the Nordic countries, where the Danish data were delivered from the Danish Cancer Registry and the Danish Cause of Death Registry with follow-up for death or emigration until the end of 2013. The proportion of patients diagnosed with kidney cancer over the age of 70 years has decreased from 43% in 1980 to 32% in 2012 in men and remained almost constant in women, around 50%. Incidence rates were at least five times higher in men aged 70 years more but there was no particular trend with time. In men aged less than 70 years, the incidence rates started increasing around 2000. The incidence rates were lower in women but with a similar pattern as in men. Mortality rates remained stable over time in persons aged 70 years or more while they decreased with time in younger women. Both the one- and the five-year relative survival increased steadily over time for all age groups but the survival was lower for patients aged 70 years or more than for younger patients. The prevalence increased three times from 1559 patients being alive after kidney cancer in 1980 to 4713 in 2012. A challenge in managing kidney cancer in the elderly is to establish interdisciplinary collaborations between different specialties, such as surgeons, clinical oncologists, and geriatricians to be able to deliver the best possible care in the future.

  11. Sadat and the Yom Kippur War, October 1973

    National Research Council Canada - National Science Library

    Grunwald, Scott; Perrin, Mark

    2001-01-01

    On October 6, 1973, the high Jewish holy day of Yom Kippur, Egyptian troops stormed across the Suez Canal in a startling attack on their bitter Israeli rival, culminating a long period of frustration...

  12. Decreases in Smoking-Related Cancer Mortality Rates Are Associated with Birth Cohort Effects in Korean Men

    Directory of Open Access Journals (Sweden)

    Yon Ho Jee

    2016-12-01

    Full Text Available Background: This study aimed to examine trends in smoking-related cancer mortality rates and to investigate the effect birth cohort on smoking-related cancer mortality in Korean men. Methods: The number of smoking-related cancer deaths and corresponding population numbers were obtained from Statistics Korea for the period 1984–2013. Joinpoint regression analysis was used to detect changes in trends in age-standardized mortality rates. Birth-cohort specific mortality rates were illustrated by 5 year age groups. Results: The age-standardized mortality rates for oropharyngeal decreased from 2003 to 2013 (annual percent change (APC: −3.1 (95% CI, −4.6 to −1.6 and lung cancers decreased from 2002 to 2013 (APC −2.4 (95% CI −2.7 to −2.2. The mortality rates for esophageal declined from 1994 to 2002 (APC −2.5 (95% CI −4.1 to −0.8 and from 2002 to 2013 (APC −5.2 (95% CI −5.7 to −4.7 and laryngeal cancer declined from 1995 to 2013 (average annual percent change (AAPC: −3.3 (95% CI −4.7 to −1.8. By the age group, the trends for the smoking-related cancer mortality except for oropharyngeal cancer have changed earlier to decrease in the younger age group. The birth-cohort specific mortality rates and age-period-cohort analysis consistently showed that all birth cohorts born after 1930 showed reduced mortality of smoking-related cancers. Conclusions: In Korean men, smoking-related cancer mortality rates have decreased. Our findings also indicate that current decreases in smoking-related cancer mortality rates have mainly been due to a decrease in the birth cohort effect, which suggest that decrease in smoking rates.

  13. Why is the death rate from lung cancer falling in the Russian Federation?

    Science.gov (United States)

    Shkolnikov, V; McKee, M; Leon, D; Chenet, L

    1999-03-01

    Age standardised death rates (European standard population) from lung cancer in the Russian Federation, have been rising since at least 1965, levelled out in the late 1980s and have subsequently decreased. The reasons for this decline are not apparent. This study seeks to identify the reasons for the decline in mortality from lung cancer in the Russian Federation in the 1990s. Changes in age-specific mortality from lung cancer in the Russian Federation between 1990 are described and age-cohort analysis, based on age-specific death rates for lung cancer is undertaken for the period 1965 to 1995. As other work has shown that any recent deterioration in coding of cause of death has been confined largely to the elderly, this suggests that the trend is not a coding artefact. Age-period-cohort analysis demonstrates the existence of a marked birth cohort effect, with two major peaks corresponding to those born around 1926 and 1938. These groups would have reached their early teens during the second world war and the period immediately after the death of Stalin, respectively. The present downward trend in death rates from lung cancer in the Russian Federation is partly due to a cohort effect and it is expected that this will soon reverse, with a second peak occurring in about 2003.

  14. Some data on Milaculum Müller, 1973

    NARCIS (Netherlands)

    Boogaard, van den M.

    1988-01-01

    An investigation of some faunas rich in Milaculum Müller, 1973 lead to the conclusion that the Milaculum animal was - at least partly - covered by plates of different morphology. Several specimens of Milaculum were encountered with adhering smaller platelets showing that the epidermal tissue of this

  15. Thyroid Cancer Incidence in New Jersey: Time Trend, Birth Cohort and Socioeconomic Status Analysis (1979-2006)

    International Nuclear Information System (INIS)

    Roche, L.M.; Niu, X.; Pawlish, K.S.; Henry, K.A.

    2011-01-01

    The study's purpose was to investigate thyroid cancer incidence time trends, birth cohort effects, and association with socioeconomic status (SES) in New Jersey (NJ), a high incidence state, using NJ State Cancer Registry data. Thyroid cancer incidence rates in each sex, nearly all age groups, two major histologists and all stages significantly increased between 1979 and 2006. For each sex, age-specific incidence rates began greatly increasing in the 1924 birth cohort and, generally, the highest thyroid cancer incidence rate for each five-year age group occurred in the latest birth cohort and diagnosis period. Thyroid cancer incidence rates were significantly higher in NJ Census tracts with higher SES and in counties with a higher percentage of insured residents. These results support further investigation into the relationship between rising thyroid cancer incidence and increasing population exposure to medical (including diagnostic) radiation, as well as widespread use of more sensitive diagnostic techniques

  16. Are meat and heme iron intake associated with pancreatic cancer? Results from the NIH-AARP Diet and Health Cohort

    Science.gov (United States)

    Taunk, Pulkit; Hecht, Eric; Stolzenberg-Solomon, Rachael

    2015-01-01

    Several studies on pancreatic cancer have reported significant positive associations for intake of red meat but null associations for heme iron. We assessed total, red, white, and processed meat intake, meat cooking methods and doneness, and heme iron and mutagen intake in relation to pancreatic cancer in the NIH-AARP Diet and Health Study cohort. 322,846 participants (187,265 men; 135,581 women) successfully completed and returned the food frequency questionnaire between 1995–1996. After a mean follow-up of 9.2 years (up to 10.17 years), 1,417 individuals (895 men, 522 women) developed exocrine pancreatic cancer. Cox proportional hazard models were used to calculate hazard ratios (HR) and 95% confidence intervals (CI), and trends were calculated using the median value of each quantile. Models incorporated age as the time metric and were adjusted for smoking history, BMI, self-reported diabetes, and energy-adjusted saturated fat. Pancreatic cancer risk significantly increased with intake of total meat (Q5 vs. Q1 HR=1.20, 95% CI 1.02–1.42, p-trend=0.03), red meat (HR=1.22, 95% CI 1.01–1.48, p-trend=0.02), high-temperature cooked meat (HR=1.21, 95% CI 1.00–1.45, p-trend=0.02), grilled/barbequed meat (HR=1.24, 95% CI 1.03–1.50, p-trend=0.007), well/very well done meat (HR=1.32, 95% CI 1.10–1.58, p-trend = 0.005), and heme iron from red meat (Q4 vs. Q1 HR=1.21, 95% CI 1.01–1.45, p-trend=0.04). When stratified by sex, these associations remained significant in men but not women except for white meat intake in women (HR = 1.33, 95% CI 1.02–1.74, p-trend = 0.04). Additional studies should confirm our findings that consuming heme iron from red meat increases pancreatic cancer risk. PMID:26666579

  17. Gender-Based Violence in India: Long-Term Trends

    Science.gov (United States)

    Simister, John; Mehta, Parnika S.

    2010-01-01

    This article examines long-term trends in Indian society regarding domestic violence between husband and wife, and attitudes to such violence. This article analyzes crime data and uses data from several Indian household surveys: "Work Attitudes and Spending" surveys (1992 to 2007); "World Values Survey" (1990, 1995, 2001, and…

  18. Recent trends in breast cancer incidence in US white women by county-level urban/rural and poverty status.

    Science.gov (United States)

    Hausauer, Amelia K; Keegan, Theresa H M; Chang, Ellen T; Glaser, Sally L; Howe, Holly; Clarke, Christina A

    2009-06-26

    Unprecedented declines in invasive breast cancer rates occurred in the United States between 2001 and 2004, particularly for estrogen receptor-positive tumors among non-Hispanic white women over 50 years. To understand the broader public health import of these reductions among previously unstudied populations, we utilized the largest available US cancer registry resource to describe age-adjusted invasive and in situ breast cancer incidence trends for non-Hispanic white women aged 50 to 74 years overall and by county-level rural/urban and poverty status. We obtained invasive and in situ breast cancer incidence data for the years 1997 to 2004 from 29 population-based cancer registries participating in the North American Association of Central Cancer Registries resource. Annual age-adjusted rates were examined overall and by rural/urban and poverty of patients' counties of residence at diagnosis. Joinpoint regression was used to assess trends by annual quarter of diagnosis. Between 2001 and 2004, overall invasive breast cancer incidence fell 13.2%, with greater reductions among women living in urban (-13.8%) versus rural (-7.5%) and low- (-13.0%) or middle- (-13.8%) versus high- (-9.6%) poverty counties. Most incidence rates peaked around 1999 then declined after second quarter 2002, although in rural counties, rates decreased monotonically after 1999. Similar but more attenuated patterns were seen for in situ cancers. Breast cancer rates fell more substantially in urban and low-poverty, affluent counties than in rural or high-poverty counties. These patterns likely reflect a major influence of reductions in hormone therapy use after July 2002 but cannot exclude possible effects due to screening patterns, particularly among rural populations where hormone therapy use was probably less prevalent.

  19. Global Update and Trends of Hidden Hunger, 1995-2011: The Hidden Hunger Index.

    Directory of Open Access Journals (Sweden)

    Julie C Ruel-Bergeron

    Full Text Available Deficiencies in essential vitamins and minerals-also termed hidden hunger-are pervasive and hold negative consequences for the cognitive and physical development of children.This analysis evaluates the change in hidden hunger over time in the form of one composite indicator-the Hidden Hunger Index (HHI-using an unweighted average of prevalence estimates from the Nutrition Impact Model Study for anemia due to iron deficiency, vitamin A deficiency, and stunting (used as a proxy indicator for zinc deficiency. Net changes from 1995-2011 and population weighted regional means for various time periods are measured.Globally, hidden hunger improved (-6.7 net change in HHI from 1995-2011. Africa was the only region to see a deterioration in hidden hunger (+1.9 over the studied time period; East Asia and the Pacific performed exceptionally well (-13.0, while other regions improved only slightly. Improvements in HHI were mostly due to reductions in zinc and vitamin A deficiencies, while anemia due to iron deficiency persisted and even increased.This analysis is critical for informing and tracking the impact of policy and programmatic efforts to reduce micronutrient deficiencies, to advance the global nutrition agenda, and to achieve the Millennium Development Goals (MDGs. However, there remains an unmet need to invest in gathering frequent, nationally representative, high-quality micronutrient data as we renew our efforts to scale up nutrition, and as we enter the post-2015 development agenda.Preparation of this manuscript was funded by Sight and Life. There was no funding involved in the study design, data collection, analysis, or decision to publish.

  20. Trends in the incidence of nonmelanoma skin cancer in Denmark 1978-2007: Rapid incidence increase among young Danish women

    DEFF Research Database (Denmark)

    Birch-Johansen, Fatima; Jensen, Allan; Mortensen, Lone

    2010-01-01

    Nonmelanoma skin cancer (NMSC) is the most common cancer among Caucasian populations worldwide, and incidence rates are increasing. However, NMSC data are not routinely collected by cancer registries, but Denmark has extensive registration of NMSC in two nationwide population-based registries. We...... assessed incidence trends of NMSC in Denmark from 1978 to 2007. Data for basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) were obtained from the Danish Cancer Registry and the Danish Registry of Pathology. For both genders, age-specific incidence rates and overall incidence rates, age...

  1. Energy policy programmes of the Federal Government 1973 to 2017; Energiepolitische Programme der Bundesregierung 1973 bis 2017

    Energy Technology Data Exchange (ETDEWEB)

    Schiffer, Hans-Wilhelm [World Energy Council, London (United Kingdom). World Energy Resources

    2017-11-15

    An analysis of the energy policy programs presented since 1973 shows that all government coalitions have been known in the past 45 years in principle for the objectives of security of supply, efficiency and affordability as well as environmental protection and conservation of resources - together with the statement that these goals should be pursued on an equal footing. In fact, there has never been this ''consonance'' of goals. Rather, concrete events or political currents have led to a changing prioritization of individual goals. At the same time, the intensity of government intervention in the management of supply and demand has changed. [German] Eine Analyse der seit 1973 vorgelegten energiepolitischen Programme zeigt: Alle Regierungskoalitionen haben sich in den vergangenen 45 Jahren im Grundsatz zu den Zielen Versorgungssicherheit, Wirtschaftlichkeit und Bezahlbarkeit sowie Umweltschutz und Ressourcenschonung bekannt - verknuepft mit der Aussage, dass diese Ziele gleichrangig zu verfolgen seien. Tatsaechlich hat es diesen ''Gleichklang'' der Ziele nie gegeben. Konkrete Ereignisse oder politische Stroemungen haben vielmehr zu einer wechselnden Priorisierung einzelner Ziele gefuehrt. Parallel dazu hat sich die Eingriffsintensitaet des Staates in die Steuerung von Angebot und Nachfrage veraendert.

  2. African Programme For Onchocerciasis Control 1995-2015: model-estimated health impact and cost.

    Science.gov (United States)

    Coffeng, Luc E; Stolk, Wilma A; Zouré, Honorat G M; Veerman, J Lennert; Agblewonu, Koffi B; Murdoch, Michele E; Noma, Mounkaila; Fobi, Grace; Richardus, Jan Hendrik; Bundy, Donald A P; Habbema, Dik; de Vlas, Sake J; Amazigo, Uche V

    2013-01-01

    Onchocerciasis causes a considerable disease burden in Africa, mainly through skin and eye disease. Since 1995, the African Programme for Onchocerciasis Control (APOC) has coordinated annual mass treatment with ivermectin in 16 countries. In this study, we estimate the health impact of APOC and the associated costs from a program perspective up to 2010 and provide expected trends up to 2015. With data on pre-control prevalence of infection and population coverage of mass treatment, we simulated trends in infection, blindness, visual impairment, and severe itch using the micro-simulation model ONCHOSIM, and estimated disability-adjusted life years (DALYs) lost due to onchocerciasis. We assessed financial costs for APOC, beneficiary governments, and non-governmental development organizations, excluding cost of donated drugs. We estimated that between 1995 and 2010, mass treatment with ivermectin averted 8.2 million DALYs due to onchocerciasis in APOC areas, at a nominal cost of about US$257 million. We expect that APOC will avert another 9.2 million DALYs between 2011 and 2015, at a nominal cost of US$221 million. Our simulations suggest that APOC has had a remarkable impact on population health in Africa between 1995 and 2010. This health impact is predicted to double during the subsequent five years of the program, through to 2015. APOC is a highly cost-effective public health program. Given the anticipated elimination of onchocerciasis from some APOC areas, we expect even more health gains and a more favorable cost-effectiveness of mass treatment with ivermectin in the near future.

  3. African Programme For Onchocerciasis Control 1995-2015: model-estimated health impact and cost.

    Directory of Open Access Journals (Sweden)

    Luc E Coffeng

    Full Text Available Onchocerciasis causes a considerable disease burden in Africa, mainly through skin and eye disease. Since 1995, the African Programme for Onchocerciasis Control (APOC has coordinated annual mass treatment with ivermectin in 16 countries. In this study, we estimate the health impact of APOC and the associated costs from a program perspective up to 2010 and provide expected trends up to 2015.With data on pre-control prevalence of infection and population coverage of mass treatment, we simulated trends in infection, blindness, visual impairment, and severe itch using the micro-simulation model ONCHOSIM, and estimated disability-adjusted life years (DALYs lost due to onchocerciasis. We assessed financial costs for APOC, beneficiary governments, and non-governmental development organizations, excluding cost of donated drugs. We estimated that between 1995 and 2010, mass treatment with ivermectin averted 8.2 million DALYs due to onchocerciasis in APOC areas, at a nominal cost of about US$257 million. We expect that APOC will avert another 9.2 million DALYs between 2011 and 2015, at a nominal cost of US$221 million.Our simulations suggest that APOC has had a remarkable impact on population health in Africa between 1995 and 2010. This health impact is predicted to double during the subsequent five years of the program, through to 2015. APOC is a highly cost-effective public health program. Given the anticipated elimination of onchocerciasis from some APOC areas, we expect even more health gains and a more favorable cost-effectiveness of mass treatment with ivermectin in the near future.

  4. Trends of lip, oral cavity and oropharyngeal cancers in Australia 1982–2008: overall good news but with rising rates in the oropharynx

    International Nuclear Information System (INIS)

    Ariyawardana, Anura; Johnson, Newell W

    2013-01-01

    Considerable global variation in the incidence of lip, of oral cavity and of pharyngeal cancers exists. Whilst this reflects regional or population differences in risk, interpretation is uncertain due to heterogeneity of definitions of sites and of sub-sites within this anatomically diverse region. For Australia, limited data on sub-sites have been published. This study examines age-standardised incidence trends and demography from 1982 to 2008, the latest data available. Numbers of cases within ICD10:C00-C14 were obtained from the Australian Institute of Health and Welfare, recorded by sex, age, and sub-site. Raw data were re-analysed to calculate crude, age-specific and age-standardised incidence using Segi’s world-standard population. Time-trends were analysed using Joinpoint regression. Lip, Oral Cavity and Pharyngeal (excluding nasopharynx) cancers, considered together, show a biphasic trend: in men rising 0.9% pa from 1982 to 1992, and declining 1.6% pa between 1992 and 2008. For females: rises of 2.0% pa 1982–1997; declines of 2.8% pa 1997–2008. Lip cancer is declining especially significantly. When the Oropharynx is considered separately, steadily increasing trends of 1.2% pa for men and 0.8% pa for women were observed from 1982 to 2008. Although overall rates of lip/oral/oropharyngeal cancer are declining in Australia, these are still high. This study revealed steady increases in cancers of the oropharynx, beginning in the late 1990s. Continued efforts to reduce the burden of these cancers are needed, focused on reduction of the traditional risk factors of alcohol and tobacco, and with special emphasis on the possible role of human papillomavirus and sexual hygiene for cancers of the oropharynx

  5. Long-term trends in the total electron content (TEC)

    Science.gov (United States)

    Laštovička, Jan

    2017-04-01

    The long-term trends in the total electron content (TEC) have very little been studied. Lean et al. (2011; J. Geophys. Res., 116, A00H04, doi:10.1029/2010JA016378) studied trends in TEC globally based on JPL maps for 1995-2010. However, their trends appear to be too positive, which is not plausible taking into account the trends in other ionospheric parameters. Therefore they prefer the less positive trends calculated under the assumption of the same level of solar activity in solar cycle minima 22/23 and 23/24. However, as it is now clear, this is not a correct assumption. Lastovicka (2013; J. Geophys. Res. Space Phys., 118, 3831-3835, doi:10.1002/jgra.50261) selected a region around Florence, Italy, as a region with available historical TEC data based on Faraday rotation measurements and remarkably larger than average trends in TEC by Lean et al. (2011). Historical data from Florence provide no trend in TEC. However, foF2 from Juliusruh provide slight negative trends for 1976-1996 but no trends for 1995-2010. Thus the question of reality of trends by Lean et al. (2011) remained open. Here we use TEC from GIM and JPL data for two European regions with high Lean's trends, regions around Florence and around Prague, using 10-14 LT medians, 1998-2015, yearly average values. A classical approach is applied. First a model of solar activity dependence of TEC is constructed separately for each region from all data. Then model data are subtracted from experimental data and analysis is made with residuals. This analysis shows that early data (1998-2001) are by several TECU lower than they should be according to solar activity, the year 2002 is intermediate and in 2003-2015 the data fit well a weak or rather no trend of TEC. The change in TEC data does not seem to be jump-like, it lasted at least a year, if not longer. Thus the positive TEC trends reported by Lean et al. (2011) appear to be affected by data problem; real trends are evidently less positive if any.

  6. Wind turbine concept market penetration over 10 years (1995-2004)

    International Nuclear Information System (INIS)

    Hansen, Anca D.; Hansen, Lars H.

    2006-01-01

    The aim of this article is to investigate the market penetration and share of different wind turbine concepts during the years 1995-2004, a period that represents the maturational era of the modern wind power industry. A detailed overview is given based on suppliers' market data and concept evaluation for each individual wind turbine type sold by the Top Ten suppliers over the selected decade. The investigation is processing information on approximately 160 wind turbine types from 22 different manufacturers that have featured in the Top Ten list of wind turbine suppliers during 1995-2004. The analysis is based on comprehensive data covering approximately 97% of the cumulative wind power installed worldwide at the end of 2004. The article also provides an overall perspective on contemporary wind turbine concepts, classified with respect to both their speed control ability and power control type. Current and future trends for wind turbine concepts are discussed. (Author)

  7. Shifting Patterns of the HIV Epidemic in Southwest China: A Case Study Based on Sentinel Surveillance, 1995-2012.

    Science.gov (United States)

    Chow, Eric P F; Gao, Liangmin; Chen, Liang; Jing, Jun; Zhang, Lei

    2015-06-01

    The HIV epidemic is experiencing a rapid shift in transmission profile in China. This study aims to examine the changes in magnitude, transmission pattern, and trend of the HIV epidemic in a typical Southwest Chinese prefecture over the period of 1995-2012. HIV surveillance data from the web-based reporting system were analyzed during this period. We investigated the temporal trends in the changing characteristics of HIV transmission, the HIV disease burden in key affected populations, and assessed the impacts on HIV disease progression due to scale-up of antiretroviral treatment. A total of 3556 HIV/AIDS cases were reported in Yuxi prefecture, Yunnan, over the study period. The number of HIV tests conducted has dramatically increased from 1041 in 1995 to 247,859 in 2012, resulting in a substantial increase in HIV diagnoses from 11 cases to 327 cases over the same period. Since 2005, cumulatively 1250 eligible people living with HIV (PLHIV) have received combination antiretroviral therapy which reduced AIDS disease progression from 9.0% (95% CI: 6.7-11.4%) in 1995 to 0.1% (0-0.3%) in 2012 (ptrend=0.0002). The primary mode of HIV transmission has been shifted from injection sharing (71.9% diagnoses in 1995-2004) to unsafe sexual contacts (82.6% diagnoses in 2012). Yuxi prefecture is experiencing a concentrated but shifting HIV epidemic. Scale-up of HIV testing is essential to effective sentinel surveillance and enhancing early diagnosis and treatment in PLHIV.

  8. Secular Trends in Mortality From Common Cancers in the United States by Educational Attainment, 1993?2001

    OpenAIRE

    Kinsey, Tracy; Jemal, Ahmedin; Liff, Jonathan; Ward, Elizabeth; Thun, Michael

    2008-01-01

    Background Death rates for the four major cancer sites (lung, breast, prostate, and colon and rectum) have declined steadily in the United States among persons aged 25?64 years since the early 1990s. We used national data to examine these trends in relation to educational attainment. Methods We calculated age-standardized death rates for each of the four cancers by level of education among 25- to 64-year-old non-Hispanic white and non-Hispanic black men and women for 1993 through 2001 using d...

  9. The Effects of Voluntary Return Programmes on Migration Flows in the Context of the 1973/74 and 2008/09 Economic Crises

    Directory of Open Access Journals (Sweden)

    Piotr Plewa

    2012-10-01

    Full Text Available The article analyses Spain’s voluntary return policies, including the programme instituted specifically to assist migrants affected by the 2008/09 crisis. Voluntary return policies were implemented in Europe in the context of the 1973/4 crisis. Just like the Western European programmes of the 1970s and the 1980s, the current Spanish voluntary return policies also only elicited the cooperation of small numbers of migrants and countries of origin. The article recommends four broader policy measures to tackle the emerging trend whereby a considerable proportion of migrants will stay in Spain rather than repatriate.

  10. Cancer in atomic bomb survivors

    International Nuclear Information System (INIS)

    Shigematsu, I.; Kagan, A.

    1986-01-01

    This book presents information on the following topics: sampling of atomic bomb survivors and method of cancer detection in Hiroshima and Nagasaki; atomic bomb dosimetry for epidemiological studies of survivors in Hiroshima and Nagasaki; tumor and tissue registries in Hiroshima and Nagasaki; the cancer registry in Nagasaki, with atomic bomb survivor data, 1973-1977; cancer mortality; methods for study of delayed health effects of a-bomb radiation; experimental radiation carcinogenesis in rodents; leukemia, multiple myeloma, and malignant lymphoma; cancer of the thyroid and salivary glands; malignant tumors in atomic bomb survivors with special reference to the pathology of stomach and lung cancer; colorectal cancer among atomic bomb survivors; breast cancer in atomic bomb survivors; and ovarian neoplasms in atomic bomb survirors

  11. EL IMPACTO DE LA CRISIS DEL PETRÓLEO DE 1973 EN EL CONTEXTO ECONÓMICO ESPAÑOL = THE OIL CRISIS OF 1973 AND ITS IMPACT IN THE SPANISH ECONOMIC CONTEXT

    Directory of Open Access Journals (Sweden)

    José María Lorca Alcalá

    2014-05-01

    Full Text Available La crisis del petróleo de 1973 después del corte de suministro de la OPEP a raíz de la guerra de Yom Kippur (octubre de 1973 afecta especialmente a nuestro país tradicionalmente consumidor de altos niveles de energía y una predisposición gubernamental a mantener sus precios bajos. Los documentos manejados pertenecen al Ministerio de Industria y a partir de ellos comprobamos el interés por absorber la crisis vía presupuestos, a través del superávit de la balanza de pagos y garantizando un precio bajo al fuel-oil.The oil crisis in 1973 after the outage of OPEC following the Yom Kippur War (October 1973 particularly affects our country traditionally high consumer of energy and with a government willingness to keep prices low. Handled documents belong to the Ministry of Industry and checking them we observe the target to absorb this situation via budget crisis, through the surplus of the balance of payments and ensuring low fuel oil price.

  12. Preliminary mortality survey from 1973 to 1977 of Japanese radiological technologists and analyses of the association of mortality with cumulative doses

    International Nuclear Information System (INIS)

    Aoyama, Takashi; Ishizaka, Masatsuna; Yamamoto, Yoichi; Kano, Eiichi; Nikaido, Osamu.

    1981-01-01

    The Japan Association of Radiologic Technologists reported that, from 1941 to 1978, 395 deaths occurred among Japanese radiological technologists who belong to the association. Using these data, Sakka, Kitabatake and colleagues, and the present authors studied mortality and cause of death among these technologists for 11 years from 1955 to 1965, for 7 years from 1966 to 1972, and for 5 years from 1973 to 1977, respectively. In general, the number of cancer deaths in the three studies was less than expected. However, Kitabatake et al. and the present authors found that deaths from skin cancer were significantly more frequent than expected. The present authors recently estimated the cumulative doses of radiation exposure for the majority of deaths (268 out of 395). The mean dose of radiation related to cancer deaths was then compared with that for non-cancer deaths. Also the proportional mortality ratios for cancers were observed in relation to the estimated dose level. In the present study, however, statistical tests to assess for the relationship between mortality and dose of radiation exposure showed no correlation, for the majority of deaths from cancer. (author)

  13. Global Update and Trends of Hidden Hunger, 1995-2011: The Hidden Hunger Index

    Science.gov (United States)

    Stevens, Gretchen A.; Ezzati, Majid; Black, Robert E.; Kraemer, Klaus

    2015-01-01

    Background Deficiencies in essential vitamins and minerals–also termed hidden hunger–are pervasive and hold negative consequences for the cognitive and physical development of children. Methods This analysis evaluates the change in hidden hunger over time in the form of one composite indicator–the Hidden Hunger Index (HHI)–using an unweighted average of prevalence estimates from the Nutrition Impact Model Study for anemia due to iron deficiency, vitamin A deficiency, and stunting (used as a proxy indicator for zinc deficiency). Net changes from 1995–2011 and population weighted regional means for various time periods are measured. Findings Globally, hidden hunger improved (-6.7 net change in HHI) from 1995–2011. Africa was the only region to see a deterioration in hidden hunger (+1.9) over the studied time period; East Asia and the Pacific performed exceptionally well (-13.0), while other regions improved only slightly. Improvements in HHI were mostly due to reductions in zinc and vitamin A deficiencies, while anemia due to iron deficiency persisted and even increased. Interpretation This analysis is critical for informing and tracking the impact of policy and programmatic efforts to reduce micronutrient deficiencies, to advance the global nutrition agenda, and to achieve the Millennium Development Goals (MDGs). However, there remains an unmet need to invest in gathering frequent, nationally representative, high-quality micronutrient data as we renew our efforts to scale up nutrition, and as we enter the post-2015 development agenda. Funding Preparation of this manuscript was funded by Sight and Life. There was no funding involved in the study design, data collection, analysis, or decision to publish. PMID:26673631

  14. Recent trends in breast cancer incidence in US white women by county-level urban/rural and poverty status

    Directory of Open Access Journals (Sweden)

    Keegan Theresa HM

    2009-06-01

    Full Text Available Abstract Background Unprecedented declines in invasive breast cancer rates occurred in the United States between 2001 and 2004, particularly for estrogen receptor-positive tumors among non-Hispanic white women over 50 years. To understand the broader public health import of these reductions among previously unstudied populations, we utilized the largest available US cancer registry resource to describe age-adjusted invasive and in situ breast cancer incidence trends for non-Hispanic white women aged 50 to 74 years overall and by county-level rural/urban and poverty status. Methods We obtained invasive and in situ breast cancer incidence data for the years 1997 to 2004 from 29 population-based cancer registries participating in the North American Association of Central Cancer Registries resource. Annual age-adjusted rates were examined overall and by rural/urban and poverty of patients' counties of residence at diagnosis. Joinpoint regression was used to assess trends by annual quarter of diagnosis. Results Between 2001 and 2004, overall invasive breast cancer incidence fell 13.2%, with greater reductions among women living in urban (-13.8% versus rural (-7.5% and low- (-13.0% or middle- (-13.8% versus high- (-9.6% poverty counties. Most incidence rates peaked around 1999 then declined after second quarter 2002, although in rural counties, rates decreased monotonically after 1999. Similar but more attenuated patterns were seen for in situ cancers. Conclusion Breast cancer rates fell more substantially in urban and low-poverty, affluent counties than in rural or high-poverty counties. These patterns likely reflect a major influence of reductions in hormone therapy use after July 2002 but cannot exclude possible effects due to screening patterns, particularly among rural populations where hormone therapy use was probably less prevalent.

  15. Pancreatic cancer and exposure to dietary nitrate and nitrite in the NIH-AARP Diet and Health Study.

    Science.gov (United States)

    Aschebrook-Kilfoy, Briseis; Cross, Amanda J; Stolzenberg-Solomon, Rachael Z; Schatzkin, Arthur; Hollenbeck, Albert R; Sinha, Rashmi; Ward, Mary H

    2011-08-01

    Nitrate and nitrite are precursors of N-nitroso compounds, which induce tumors of the pancreas in animals. The authors evaluated the relation of dietary nitrate and nitrite to pancreatic cancer risk in the NIH-AARP Diet and Health Study. Nitrate and nitrite intakes were assessed at baseline using a 124-item food frequency questionnaire. During approximately 10 years of follow-up between 1995 and 2006, 1,728 incident pancreatic cancer cases were identified. There was no association between total nitrate or nitrite intake and pancreatic cancer in men or women. However, men in the highest quintile of summed nitrate/nitrite intake from processed meat had a nonsignificantly elevated risk of pancreatic cancer (hazard ratio = 1.18, 95% confidence interval: 0.95, 1.47; P-trend = 0.11). The authors observed a stronger increase in risk among men for nitrate/nitrite intake from processed meat at ages 12-13 years (highest quintile vs. lowest: hazard ratio = 1.32, 95% confidence interval: 0.99, 1.76; P-trend = 0.11), though the relation did not achieve statistical significance. The authors found no associations between adult or adolescent nitrate or nitrite intake from processed meats and pancreatic cancer among women. These results provide modest evidence that processed meat sources of dietary nitrate and nitrite may be associated with pancreatic cancer among men and provide no support for the hypothesis in women.

  16. Increasing trends in kidney cancer over the last 2 decades in Saudi Arabia.

    Science.gov (United States)

    Alkhateeb, Sultan S; Alkhateeb, Jawaher M; Alrashidi, Eman A

    2015-06-01

    To examine the trends of kidney cancer over the last 2 decades in a subset of a Saudi Arabian population.   We conducted a retrospective study in a tertiary care center including all adult patients with primary kidney cancer who presented and were managed between 1990 and 2010. The time period was split into 4 quartiles, and variables tested and compared using chi-square, T-test, and Kaplan-Meier curves for survival.   The total was 215 patients with a mean age of 57.8 years. There was an increase in the number of kidney cancer cases over the last 2 decades. There was no significant difference in the mode of presentation or stage distribution between quartiles. A significant change was observed in the management towards minimally invasive and nephron-sparing surgeries (p less than 0.001). There was no change in recurrence-free and disease-specific survival over the last 20 years.   There have been an increasing number of kidney cancer patients over the last 2 decades with no observed migration towards more incidental and low stage tumors as compared with developed countries.

  17. Consumption of materials in the United States, 1900-1995

    Science.gov (United States)

    Matos, G.; Wagner, L.; ,

    1998-01-01

    The flows of nonfood and nonfuel materials through the economy have significant impact on our lives and the world around us. Growing populations and economies demand more goods, services, and infrastructure. Since the beginning of the twentieth century, the types of materials consumed in the United States have significantly changed. In 1900, on a per-weight basis, almost half of the materials consumed were from renewable resources, such as wood, fibers, and agricultural products, the rest being derived from nonrenewable resources. By 1995, the consumption of renewable resources had declined dramatically, to only 8% of total consumption. During this century, the quantity of materials consumed has grown, from 161 million metric tons in 1900 to 2.8 billion metric tons by 1995, an equivalent of 10 metric tons per person per year. Of all the materials consumed during this century, more than half were consumed in the last 25 years. This paper examines the general historical shifts in materials consumption and presents an analysis of different measurements of materials use and the significance of their trends.

  18. Lung Cancer in a Rural Area of China: Rapid Rise in Incidence and Poor Improvement in Survival.

    Science.gov (United States)

    Yang, Juan; Zhu, Jian; Zhang, Yong-Hui; Chen, Yong-Sheng; Ding, Lu-Lu; Kensler, Thomas W; Chen, Jian-Guo

    2015-01-01

    Lung cancer has been a major health problem in developed countries for several decades, and has emerged recently as the leading cause of cancer death in many developing countries. The incidence of lung cancer appears to be increasing more rapidly in rural than in urban areas of China. This paper presents the trends of lung cancer incidence and survival derived from a 40-year population-based cancer monitoring program in a rural area, Qidong, China. The Qidong cancer registration data of 1972- 2011 were used to calculate the crude rate, age-standardized rate by Chinese population (CASR) and by world population (WASR), birth cohort rates, and other descriptive features. Active and passive methods were used to construct the data set, with a deadline of the latest follow-up of April 30, 2012. The total number of lung cancer cases was 15,340, accounting for 16.5% of all sites combined. The crude incidence rate, CASR and WASR of this cancer were 34.1, 15.7 and 25.4 per 100,000, respectively. Males had higher crude rates than females (49.7 vs 19.0). Rapidly increasing trends were found in annual percent change resulting in lung cancer being a number one cancer site after year 2010 in Qidong. Birth cohort analysis showed incidence rates have increased for all age groups over 24 years old. The 5 year observed survival rates were 3.55% in 1973-1977, 3.92 in 1983-1987, 3.69% in 1993-1997, and 6.32% in 2003-2007. Males experienced poorer survival than did females. Lung cancer has become a major cancer-related health problem in this rural area. The rapid increases in incidence likely result from an increased cigarette smoking rate and evolving environmental risk factors. Lung cancer survival, while showing some improvement in prognosis, still remains well below that observed in the developed areas of the world.

  19. Long-term trends in the ionospheric E and F1 regions

    Directory of Open Access Journals (Sweden)

    J. Bremer

    2008-05-01

    Full Text Available Ground based ionosonde measurements are the most essential source of information about long-term variations in the ionospheric E and F1 regions. Data of such observations have been derived at many different ionospheric stations all over the world some for more than 50 years. The standard parameters foE, h'E, and foF1 are used for trend analyses in this paper. Two main problems have to be considered in these analyses. Firstly, the data series have to be homogeneous, i.e. the observations should not be disturbed by artificial steps due to technical reasons or changes in the evaluation algorithm. Secondly, the strong solar and geomagnetic influences upon the ionospheric data have carefully to be removed by an appropriate regression analysis. Otherwise the small trends in the different ionospheric parameters cannot be detected.

    The trends derived at individual stations differ markedly, however their dependence on geographic or geomagnetic latitude is only small. Nevertheless, the mean global trends estimated from the trends at the different stations show some general behaviour (positive trends in foE and foF1, negative trend in h'E which can at least qualitatively be explained by an increasing atmospheric greenhouse effect (increase of CO2 content and other greenhouse gases and decreasing ozone values. The positive foE trend is also in qualitative agreement with rocket mass spectrometer observations of ion densities in the E region. First indications could be found that the changing ozone trend at mid-latitudes (before about 1979, between 1979 until 1995, and after about 1995 modifies the estimated mean foE trend.

  20. Mapping cancer, cardiovascular and malaria research in Brazil

    Directory of Open Access Journals (Sweden)

    P.S. Rodrigues

    2000-08-01

    Full Text Available This paper presents performance indicators for the Brazilian cancer, cardiovascular and malaria research areas from 1981 to 1995. The data show an increasing number of papers since 1981 and author numbers indicate a continuous growth of the scientific community and suggest an expected impact of scientific activity on biomedical education. The data also characterize cardiovascular research as a well-established area and cancer research as a faster growing consolidating field. The 1989-1994 share of Brazilian articles among world publications shows a growing trend for the cancer (1.61 and cardiovascular (1.59 areas, and a decrease for the malaria area (0.89. The burden of the three diseases on society is contrasted by the small number of consolidated Brazilian research groups, and a questionable balance of thematic activity, especially with regard to malaria. Brazilian periodicals play an important role in increasing the international visibility of science produced in the country. Cancer and cardiovascular research is strongly concentrated in the Southeastern and in Southern regions of Brazil, especially in São Paulo (at least one address from São Paulo in 64.5% of the 962 cancer articles and in 66.9% of the 2250 cardiovascular articles, the second state being Rio de Janeiro with at least one address in 14.1 and 11% of those articles, respectively. Malaria research (468 articles is more evenly distributed across the country, following the pattern of the endemic distribution of the disease. Surveying these national indicator trends can be useful to establish policies in the decision process about health sciences, medical education and public health.

  1. A decade of change: an institutional experience with breast surgery in 1995 and 2005.

    Science.gov (United States)

    Guth, Amber A; Shanker, Beth Ann; Roses, Daniel F; Axelrod, Deborah; Singh, Baljit; Toth, Hildegard; Shapiro, Richard L; Hiotis, Karen; Diflo, Thomas; Cangiarella, Joan F

    2008-01-01

    With the adoption of routine screening mammography, breast cancers are being diagnosed at earlier stages, with DCIS now accouting for 22.5% of all newly diagnosed breast cancers. This has been attributed to both increased breast cancer awareness and improvements in breast imaging techniques. How have these changes, including the increased use of image-guided sampling techniques, influenced the clinical practice of breast surgery? The institutional pathology database was queried for all breast surgeries, including breast reconstruction, performed in 1995 and 2005. Cosmetic procedures were excluded. The results were analysed utilizing the Chi-square test. Surgical indications changed during 10-year study period, with an increase in preoperatively diagnosed cancers undergoing definitive surgical management. ADH, and to a lesser extent, ALH, became indications for surgical excision. Fewer surgical biopsies were performed for indeterminate abnormalities on breast imaging, due to the introduction of stereotactic large core biopsy. While the rate of benign breast biopsies remained constant, there was a higher percentage of precancerous and DCIS cases in 2005. The overall rate of mastectomy decreased from 36.8% in 1995 to 14.5% in 2005. With the increase in sentinel node procedures, the rate of ALND dropped from 18.3% to 13.7%. Accompanying the increased recognition of early-stage cancers, the rate of positive ALND also decreased, from 43.3% to 25.0%. While the rate of benign breast biopsies has remained constant over a recent 10-year period, fewer diagnostic surgical image-guided biopsies were performed in 2005. A greater percentage of patients with breast cancer or preinvasive disease have these diagnoses determined before surgery. More preinvasive and Stage 0 cancers are undergoing surgical management. Earlier stage invasive cancers are being detected, reflected by the lower incidence of axillary nodal metastases.

  2. A Decade of Change: An Institutional Experience with Breast Surgery in 1995 and 2005

    Directory of Open Access Journals (Sweden)

    Amber A. Guth M.D.

    2008-01-01

    Full Text Available Introduction With the adoption of routine screening mammography, breast cancers are being diagnosed at earlier stages, with DCIS now accouting for 22.5% of all newly diagnosed breast cancers. This has been attributed to both increased breast cancer awareness and improvements in breast imaging techniques. How have these changes, including the increased use of image-guided sampling techniques, influenced the clinical practice of breast surgery? Methods The institutional pathology database was queried for all breast surgeries, including breast reconstruction, performed in 1995 and 2005. Cosmetic procedures were excluded. The results were analysed utilizing the Chi-square test. Results Surgical indications changed during 10-year study period, with an increase in preoperatively diagnosed cancers undergoing definitive surgical management. ADH, and to a lesser extent, ALH, became indications for surgical excision. Fewer surgical biopsies were performed for indeterminate abnormalities on breast imaging, due to the introduction of stereotactic large core biopsy. While the rate of benign breast biopsies remained constant, there was a higher percentage of precancerous and DCIS cases in 2005. The overall rate of mastectomy decreased from 36.8% in 1995 to 14.5% in 2005. With the increase in sentinel node procedures, the rate of ALND dropped from 18.3% to 13.7%. Accompanying the increased recognition of early-stage cancers, the rate of positive ALND also decreased, from 43.3% to 25.0%. Conclusions While the rate of benign breast biopsies has remained constant over a recent 10-year period, fewer diagnostic surgical image-guided biopsies were performed in 2005. A greater percentage of patients with breast cancer or preinvasive disease have these diagnoses determined before surgery. More preinvasive and Stage 0 cancers are undergoing surgical management. Earlier stage invasive cancers are being detected, reflected by the lower incidence of axillary nodal

  3. A Decade of Change: An Institutional Experience with Breast Surgery in 1995 and 2005

    Directory of Open Access Journals (Sweden)

    Amber A. Guth

    2008-01-01

    Full Text Available Introduction: With the adoption of routine screening mammography, breast cancers are being diagnosed at earlier stages, with DCIS now accouting for 22.5% of all newly diagnosed breast cancers. This has been attributed to both increased breast cancer awareness and improvements in breast imaging techniques. How have these changes, including the increased use of image-guided sampling techniques, influenced the clinical practice of breast surgery?Methods: The institutional pathology database was queried for all breast surgeries, including breast reconstruction, performed in 1995 and 2005. Cosmetic procedures were excluded. The results were analysed utilizing the Chi-square test.Results: Surgical indications changed during 10-year study period, with an increase in preoperatively diagnosed cancers undergoing definitive surgical management. ADH, and to a lesser extent, ALH, became indications for surgical excision. Fewer surgical biopsies were performed for indeterminate abnormalities on breast imaging, due to the introduction of stereotactic large core biopsy. While the rate of benign breast biopsies remained constant, there was a higher percentage of precancerous and DCIS cases in 2005. The overall rate of mastectomy decreased from 36.8% in 1995 to 14.5% in 2005. With the increase in sentinel node procedures, the rate of ALND dropped from 18.3% to 13.7%. Accompanying the increased recognition of early-stage cancers, the rate of positive ALND also decreased, from 43.3% to 25.0%.Conclusions: While the rate of benign breast biopsies has remained constant over a recent 10-year period, fewer diagnostic surgical image-guided biopsies were performed in 2005. A greater percentage of patients with breast cancer or preinvasive disease have these diagnoses determined before surgery. More preinvasive and Stage 0 cancers are undergoing surgical management. Earlier stage invasive cancers are being detected, reflected by the lower incidence of axillary nodal

  4. Mathematical competencies and the role of mathematics in physics education: A trend analysis of TIMSS Advanced 1995 and 2008

    Directory of Open Access Journals (Sweden)

    Trude Nilsen

    2013-10-01

    Full Text Available As students advance in their learning of physics over the course of their education, the requirement of mathematical applications in physics-related tasks increases, especially so in upper secondary school and in higher education. Yet there is little empirical work (particularly large-scale or longitudinal on the application of mathematics in physics education compared with the research related to the conceptual knowledge of physics. In order to clarify the nature of mathematics in physics education, we developed a theoretical framework for mathematical competencies pertinent to various physics tasks based on theoretical frameworks from mathematics and physics education. We used this synthesis of frameworks as a basis to create a model for physics competence. The framework also served as a tool for analyzing and categorizing trend items from the international large-scale survey, TIMSS Advanced 1995 and 2008. TIMSS Advanced assessed students in upper secondary school with special preparation in advanced physics and mathematics. We then investigated the changes in achievements on these categorized items across time for nations who participated in both surveys. The results from our analysis indicate that students whose overall physics achievement declined struggled the most with items requiring mathematics, especially items requiring them to handle symbols, such as manipulating equations. This finding suggests the importance of collaboration between mathematics and physics education as well as the importance of traditional algebra for physics education.

  5. Summary of spill events in Canada : 1984 - 1995

    International Nuclear Information System (INIS)

    1998-11-01

    The trends in hazardous material spill events in Canada were summarized for the 12-year period 1984 to 1995. Findings were presented on the number and quantity of spills. The report includes data on the seven major sectors that incur spills. These include the chemical, government, metallurgy, mining, petroleum, pulp and paper and service industry sectors. The causes and reasons for these spills, and any environmental impacts, are described. Case histories of four significant environmental incidents were reviewed in detail. These include a warehouse fire at Canning, Nova Scotia in 1986, a tire fire at Hagersville, Ontario in 1990, a train derailment in Hervey Junction, Quebec in 1995, and the Nestucca oil spill in Gray's Harbour near Vancouver Island, British Columbia in 1988. Equipment failure and human error were pinpointed as the most common cause of spills, followed by corrosion, material failure and storm or flood. Fifty-eight per cent of all reported spills involve oil and petroleum products. Wastes and effluents account for 89 per cent of the total quantity of reported spills. These findings make the report particularly well suited for use as a tool in developing appropriate spill prevention strategies. 15 refs., 26 tabs., 42 figs

  6. Potential Effects of a Scenario Earthquake on the Economy of Southern California: Baseline County-Level Migration Characteristics and Trends 1995-2000 and 2001-2010

    Science.gov (United States)

    Sherrouse, Benson C.; Hester, David J.

    2008-01-01

    The Multi-Hazards Demonstration Project (MHDP) is a collaboration between the U.S. Geological Survey (USGS) and various partners from the public and private sectors and academia, meant to improve Southern California's resiliency to natural hazards. In support of the MHDP objectives, the ShakeOut Scenario was developed. It describes a magnitude 7.8 earthquake along the southernmost 300 kilometers (200 miles) of the San Andreas Fault, identified by geoscientists as a plausible event that will cause moderate to strong shaking over much of the eight-county (Imperial, Kern, Los Angeles, Orange, Riverside, San Bernardino, San Diego, and Ventura) Southern California region. This report uses historical, estimated, and projected population data from several Federal and State data sources to estimate baseline characteristics and trends of the region's population migration (that is, changes in a person's place of residence over time). The analysis characterizes migration by various demographic, economic, family, and household variables for the period 1995-2000. It also uses existing estimates (beginning in 2001) of the three components of population change - births, deaths, and migration - to extrapolate near-term projections of county-level migration trends through 2010. The 2010 date was chosen to provide baseline projections corresponding to a two-year recovery period following the November 2008 date that was selected for the occurrence of the ShakeOut Scenario earthquake. The baseline characteristics and projections shall assist with evaluating the effects of inflow and outflow migration trends for alternative futures in which the simulated M7.8 earthquake either does or does not occur and the impact of the event on housing and jobs, as well as community composition and regional economy changes based on dispersion of intellectual, physical, economic, and cultural capital.

  7. Time trends and occupational variation in the incidence of testicular cancer in the Nordic countries.

    Science.gov (United States)

    Ylönen, Outi; Jyrkkiö, Sirkku; Pukkala, Eero; Syvänen, Kari; Boström, Peter J

    2018-02-20

    To describe the trends and occupational variation in the incidence of testicular cancer in the Nordic countries utilising national cancer registries, NORDCAN (NORDCAN project/database presents the incidence, mortality, prevalence and survival from >50 cancers in the Nordic countries) and NOCCA (Nordic Occupational Cancer) databases. We obtained the incidence data of testicular cancer for 5-year periods from 1960-1964 to 2000-2014 and for 5-year age-groups from the NORDCAN database. Morphological data on incident cases of seminoma and non-seminoma were obtained from national cancer registries. Age-standardised incidence rates (ASR) were calculated per 100 000 person-years (World Standard). Regression analysis was used to evaluate the annual change in the incidence of testicular cancer in each of the Nordic countries. The risk of testicular cancer in different professions was described based on NOCCA information and expressed as standardised incidence ratios (SIRs). During 2010-2014 the ASR for testicular cancer varied from 11.3 in Norway to 5.8 in Finland. Until 1998, the incidence was highest in Denmark. There has not been an increase in Denmark and Iceland since the 1990s, whilst the incidence is still strongly increasing in Norway, Sweden, and Finland. There were no remarkable changes in the ratio of seminoma and non-seminoma incidences during the past 50 years. There was no increase in the incidences in children and those of pension age. The highest significant excess risks of testicular seminoma were found in physicians (SIR 1.48, 95% confidence interval [CI] 1.07-1.99), artistic workers (SIR 1.47, 95% CI 1.06-1.99) and religious workers etc. (SIR 1.33, 95% CI 1.14-1.56). The lowest SIRs of testicular seminoma were seen amongst cooks and stewards (SIR 0.56, 95% CI 0.29-0.98), and forestry workers (SIR 0.64, 95% CI 0.47-0.86). The occupational category of administrators was the only one with a significantly elevated SIR for testicular non-seminoma (SIR 1.21, 95

  8. The effect of population-based mammography screening in Dutch municipalities on breast cancer mortality: 20 years of follow-up.

    Science.gov (United States)

    Sankatsing, Valérie D V; van Ravesteyn, Nicolien T; Heijnsdijk, Eveline A M; Looman, Caspar W N; van Luijt, Paula A; Fracheboud, Jacques; den Heeten, Gerard J; Broeders, Mireille J M; de Koning, Harry J

    2017-08-15

    Long-term follow-up data on the effects of screening are scarce, and debate exists on the relative contribution of screening versus treatment to breast cancer mortality reduction. Our aim was therefore to assess the long-term effect of screening by age and time of implementation. We obtained data on 69,630 breast cancer deaths between 1980 and 2010 by municipality (N = 431) and age of death (40-79) in the Netherlands. Breast cancer mortality trends were analyzed by defining the municipality-specific calendar year of introduction of screening as Year 0. Additionally, log-linear Poisson regression was used to estimate the turning point in the trend after Year 0, per municipality, and the annual percentage change (APC) before and after this point. Twenty years after introduction of screening breast cancer mortality was reduced by 30% in women aged 55-74 and by 34% in women aged 75-79, compared to Year 0. A similar and significant decrease was present in municipalities that started early (1987-1992) and late (1995-1997) with screening, despite the difference in availability of effective adjuvant treatment. In the age groups 55-74 and 75-79, the turning point in the trend in breast cancer mortality was estimated in Years 2 and 6 after the introduction of screening, respectively, after which mortality decreased significantly by 1.9% and 2.6% annually. These findings show that the implementation of mammography screening in Dutch municipalities is associated with a significant decline in breast cancer mortality in women aged 55-79, irrespective of time of implementation. © 2017 UICC.

  9. Tennessee health studies agreement. Annual report for year 4, January 1 - December 31, 1995

    International Nuclear Information System (INIS)

    1996-04-01

    The Tennessee Department of Health (TDH) has completed the fourth full year of the Oak Ridge Health Studies Agreement grant. This report summarizes the accomplishments and concerns of the State for the period January 1, 1995, to December 31, 1995. The focus of work during the fourth grant year was the actual work on the dose reconstruction. The final work plan for Task 5, Plan to Perform a Systematic Document Search was received in November 1994. Final work plans for Task 1, Investigation of Radioiodine from Radioactive Lanthanum Processing; Task 2, Investigation of Mercury Releases from Lithium Enrichment; Task 3, Investigation of Releases of PCBs from Oak Ridge Facilities; and Task 4, Investigation of Releases of Radionuclides from White Oak Creek to the Clinch River, were received in February 1995. Final work plans for Task 6, Investigation of the Quality of Historical Uranium Effluent Monitoring at Oak Ridge Facilities; and Task 7, Additional Screening of Materials Not Evaluated in the Dose Reconstruction Feasibility Study, were received in April 1995. ChemRisk's 4th Quarterly Report, for October through December 1995, is included in Attachment 1. Attachment 2 contains a study which developed a quality improvement program for data imported to the Tennessee Cancer Reporting System and Birth Defects Verification Program

  10. Trends in Breast Cancer Incidence Rates by Age and Stage at Diagnosis in Gharbiah, Egypt, over 10 Years (1999–2008

    Directory of Open Access Journals (Sweden)

    Kelly A. Hirko

    2013-01-01

    Full Text Available Background. This study was undertaken to evaluate trends in breast cancer incidence in Egypt from 1999 to 2008 and to make projections for breast cancer occurrence for the years 2009–2015. Patients and Methods. We utilized joinpoint regression and average annual percent change (AAPC measures with 95% confidence intervals (CI to describe the trends in breast cancer incidence rates from the Gharbiah Cancer Registry by age and stage at diagnosis and to estimate expected breast cancer caseloads for 2009–2015. Results. From 1999 to 2008, the AAPC in breast cancer incidence rates in Gharbiah significantly increased among women 50 years and older and among localized tumors (AAPC %, 95% CI, 3.1% to 8.0%. Our results predict a significant increase in breast cancer caseloads from 2009 to 2015 among women aged 30–39 (AAPC %, 95% CI, 0.9% to 1.1% and among women aged 40–49 years (AAPC %, 95% CI, 1.0% to 2.6%. Conclusion. These results have important implications for allocating limited resources, managing treatment needs, and exploring the consequences of prior interventions and/or changing risk factors in Egypt and other developing countries at the same stages of demographic and health transitions.

  11. Oral Cavity and Pharynx Cancer Incidence Trends by Subsite in the United States: Changing Gender Patterns

    Directory of Open Access Journals (Sweden)

    Linda Morris Brown

    2012-01-01

    Full Text Available Objective. To evaluate oral cavity and pharynx cancer (OCPC patterns by gender. Methods. We used Surveillance, Epidemiology, and End Results program data for 71,446 cases diagnosed during 1975–2008 to classify OCPC by anatomic subsite as potentially HPV-related or not, with oral tongue cancer considered a separate category. Results. Total OCPC rates among men were 2–4 times those among women. Among whites, total OCPC rates rose in the younger age groups due to substantial increases in successive birth cohorts for HPV-related cancers, more rapid among men than women, and oral tongue cancers, more rapid among women than men. Among blacks, total OCPC rates declined among cohorts born since 1930 reflecting the strong downward trends for HPV-unrelated sites. Among Hispanics and Asians, HPV-unrelated cancer rates generally declined, and oral tongue cancer rates appeared to be converging among young men and women. Conclusions. Decreases in total OCPC incidence reflect reductions in smoking and alcohol drinking. Rising HPV-related cancers among white men may reflect changing sexual practices. Reasons for the increasing young oral tongue cancer rates are unknown, but the narrowing of the gender differences provides a clue.

  12. Oral cancer in Cali, Colombia: a population-based analysis of incidence and mortality trends.

    Directory of Open Access Journals (Sweden)

    Dora Ordóñez

    2014-09-01

    Full Text Available Objective. To describe the time trends of the incidence and mortality rates of oral cancer (OC in Cali, Colombia between 1962-2007. Materials and methods. Age-standardized (Segi’s world population incidence (ASIR and mortality (ASMR rates for oral cancer were estimated using data from the Population-based Cancer Registry of Cali, Colombia and from the database of the Municipal Secretary of Public Health (MSPH respectively. Annual percentage change (APC was used to measure the changes in rates over time. Results. 1 637 new cases of oral cancer were registered in the CPCR and the mean age upon diagnosis was 60 years. The ASIR decreased from 1962-2007 in men APC= 1.3 (IC95%:-2.0; -0.6 and women APC= -1.0 (IC95%: -1.7; -0.4.The ASMR decreased from 1984-2001 only in men, APC=2.8 (IC95%: -4.1; -1.5. Conclusions. There was a significant decrease in the incidence and mortality rates for OC in Cali, Colombia. The type of tumor associated to these changes was the squamous cell carcinoma

  13. [Oral cancer in Cali, Colombia: a population-based analysis of incidence and mortality trends].

    Science.gov (United States)

    Ordóñez, Dora; Aragón, Natalia; García, Luz Stella; Collazos, Paola; Bravo, Luis Eduardo

    2014-01-01

    To describe the time trends of the incidence and mortality rates of oral cancer (OC) in Cali, Colombia between 1962-2007. Age-standardized (Segi's world population) incidence (ASIR) and mortality (ASMR) rates for oral cancer were estimated using data from the Population-based Cancer Registry of Cali, Colombia and from the database of the Municipal Secretary of Public Health (MSPH) respectively. Annual percentage change (APC) was used to measure the changes in rates over time. 1637 new cases of oral cancer were registered in the CPCR and the mean age upon diagnosis was 60 years. The ASIR decreased from 1962-2007 in men APC= 1.3 (IC95%:-2.0; -0.6) and women APC= -1.0 (IC95%: -1.7; -0.4).The ASMR decreased from 1984-2001 only in men, APC=2.8 (IC95%: -4.1; -1.5). There was a significant decrease in the incidence and mortality rates for OC in Cali, Colombia. The type of tumor associated to these changes was the squamous cell carcinoma.

  14. Atomic Energy Authority (Weapons Group) Act 1973

    International Nuclear Information System (INIS)

    1973-01-01

    This Act, which came into force on 6th March 1973 and modified Section 2 of the Atomic Energy Authority Act 1954 in respect of the Authority's power to do work on explosive nuclear devices, made provision for the transfer to the Secretary of State for Defence of the Weapons Group of the Atomic Energy Authority. (NEA) [fr

  15. The prevalence and incidence of active syphilis in women in Morocco, 1995-2016: Model-based estimation and implications for STI surveillance.

    Science.gov (United States)

    Bennani, Aziza; El-Kettani, Amina; Hançali, Amina; El-Rhilani, Houssine; Alami, Kamal; Youbi, Mohamed; Rowley, Jane; Abu-Raddad, Laith; Smolak, Alex; Taylor, Melanie; Mahiané, Guy; Stover, John; Korenromp, Eline L

    2017-01-01

    Evolving health priorities and resource constraints mean that countries require data on trends in sexually transmitted infections (STI) burden, to inform program planning and resource allocation. We applied the Spectrum STI estimation tool to estimate the prevalence and incidence of active syphilis in adult women in Morocco over 1995 to 2016. The results from the analysis are being used to inform Morocco's national HIV/STI strategy, target setting and program evaluation. Syphilis prevalence levels and trends were fitted through logistic regression to data from surveys in antenatal clinics, women attending family planning clinics and other general adult populations, as available post-1995. Prevalence data were adjusted for diagnostic test performance, and for the contribution of higher-risk populations not sampled in surveys. Incidence was inferred from prevalence by adjusting for the average duration of infection with active syphilis. In 2016, active syphilis prevalence was estimated to be 0.56% in women 15 to 49 years of age (95% confidence interval, CI: 0.3%-1.0%), and around 21,675 (10,612-37,198) new syphilis infections have occurred. The analysis shows a steady decline in prevalence from 1995, when the prevalence was estimated to be 1.8% (1.0-3.5%). The decline was consistent with decreasing prevalences observed in TB patients, fishermen and prisoners followed over 2000-2012 through sentinel surveillance, and with a decline since 2003 in national HIV incidence estimated earlier through independent modelling. Periodic population-based surveys allowed Morocco to estimate syphilis prevalence and incidence trends. This first-ever undertaking engaged and focused national stakeholders, and confirmed the still considerable syphilis burden. The latest survey was done in 2012 and so the trends are relatively uncertain after 2012. From 2017 Morocco plans to implement a system to record data from routine antenatal programmatic screening, which should help update and re

  16. Land cover change of watersheds in Southern Guam from 1973 to 2001.

    Science.gov (United States)

    Wen, Yuming; Khosrowpanah, Shahram; Heitz, Leroy

    2011-08-01

    Land cover change can be caused by human-induced activities and natural forces. Land cover change in watershed level has been a main concern for a long time in the world since watersheds play an important role in our life and environment. This paper is focused on how to apply Landsat Multi-Spectral Scanner (MSS) satellite image of 1973 and Landsat Thematic Mapper (TM) satellite image of 2001 to determine the land cover changes of coastal watersheds from 1973 to 2001. GIS and remote sensing are integrated to derive land cover information from Landsat satellite images of 1973 and 2001. The land cover classification is based on supervised classification method in remote sensing software ERDAS IMAGINE. Historical GIS data is used to replace the areas covered by clouds or shadows in the image of 1973 to improve classification accuracy. Then, temporal land cover is utilized to determine land cover change of coastal watersheds in southern Guam. The overall classification accuracies for Landsat MSS image of 1973 and Landsat TM image of 2001 are 82.74% and 90.42%, respectively. The overall classification of Landsat MSS image is particularly satisfactory considering its coarse spatial resolution and relatively bad data quality because of lots of clouds and shadows in the image. Watershed land cover change in southern Guam is affected greatly by anthropogenic activities. However, natural forces also affect land cover in space and time. Land cover information and change in watersheds can be applied for watershed management and planning, and environmental modeling and assessment. Based on spatio-temporal land cover information, the interaction behavior between human and environment may be evaluated. The findings in this research will be useful to similar research in other tropical islands.

  17. Trends in Costs of Thyroid Disease Treatment in Denmark during 1995-2015

    DEFF Research Database (Denmark)

    Møllehave, Line Tang; Linneberg, Allan; Skaaby, Tea

    2018-01-01

    treatment) was obtained from nationwide registers. Costs were valued at 2015 prices using sales prices for medicines and the Danish Diagnosis-Related Group (DRG) and Danish Ambulatory Grouping System (DAGS) tariffs of surgeries/radioiodine treatments. Results were adjusted for changes in population size...... and age and sex distribution. Results: The total direct medicine and hospital costs of thyroid disease treatment increased from EUR ∼190,000 per 100,000 persons in 1995 to EUR ∼270,000 per 100,000 persons in 2015. This was mainly due to linearly increased costs of thyroid hormone therapy and increased...... costs of thyroid surgery since 2008. Costs of antithyroid medication increased slightly and transiently after IF, while costs of radioiodine treatment remained constant. Costs of thyroid hormone therapy and thyroid surgery did not follow the development in the prevalence of hypothyroidism and structural...

  18. African Programme for Onchocerciasis Control 1995–2015: Model-Estimated Health Impact and Cost

    Science.gov (United States)

    Coffeng, Luc E.; Stolk, Wilma A.; Zouré, Honorat G. M.; Veerman, J. Lennert; Agblewonu, Koffi B.; Murdoch, Michele E.; Noma, Mounkaila; Fobi, Grace; Richardus, Jan Hendrik; Bundy, Donald A. P.; Habbema, Dik; de Vlas, Sake J.; Amazigo, Uche V.

    2013-01-01

    Background Onchocerciasis causes a considerable disease burden in Africa, mainly through skin and eye disease. Since 1995, the African Programme for Onchocerciasis Control (APOC) has coordinated annual mass treatment with ivermectin in 16 countries. In this study, we estimate the health impact of APOC and the associated costs from a program perspective up to 2010 and provide expected trends up to 2015. Methods and Findings With data on pre-control prevalence of infection and population coverage of mass treatment, we simulated trends in infection, blindness, visual impairment, and severe itch using the micro-simulation model ONCHOSIM, and estimated disability-adjusted life years (DALYs) lost due to onchocerciasis. We assessed financial costs for APOC, beneficiary governments, and non-governmental development organizations, excluding cost of donated drugs. We estimated that between 1995 and 2010, mass treatment with ivermectin averted 8.2 million DALYs due to onchocerciasis in APOC areas, at a nominal cost of about US$257 million. We expect that APOC will avert another 9.2 million DALYs between 2011 and 2015, at a nominal cost of US$221 million. Conclusions Our simulations suggest that APOC has had a remarkable impact on population health in Africa between 1995 and 2010. This health impact is predicted to double during the subsequent five years of the program, through to 2015. APOC is a highly cost-effective public health program. Given the anticipated elimination of onchocerciasis from some APOC areas, we expect even more health gains and a more favorable cost-effectiveness of mass treatment with ivermectin in the near future. PMID:23383355

  19. Population-wide weight loss and regain in relation to diabetes burden and cardiovascular mortality in Cuba 1980-2010: repeated cross sectional surveys and ecological comparison of secular trends.

    Science.gov (United States)

    Franco, Manuel; Bilal, Usama; Orduñez, Pedro; Benet, Mikhail; Morejón, Alain; Caballero, Benjamín; Kennelly, Joan F; Cooper, Richard S

    2013-04-09

    To evaluate the associations between population-wide loss and gain in weight with diabetes prevalence, incidence, and mortality, as well as cardiovascular and cancer mortality trends, in Cuba over a 30 year interval. Repeated cross sectional surveys and ecological comparison of secular trends. Cuba and the province of Cienfuegos, from 1980 to 2010. Measurements in Cienfuegos included a representative sample of 1657, 1351, 1667, and 1492 adults in 1991, 1995, 2001, and 2010, respectively. National surveys included a representative sample of 14 304, 22 851, and 8031 participants in 1995, 2001, and 2010, respectively. Changes in smoking, daily energy intake, physical activity, and body weight were tracked from 1980 to 2010 using national and regional surveys. Data for diabetes prevalence and incidence were obtained from national population based registries. Mortality trends were modelled using national vital statistics. Rapid declines in diabetes and heart disease accompanied an average population-wide loss of 5.5 kg in weight, driven by an economic crisis in the mid-1990s. A rebound in population weight followed in 1995 (33.5% prevalence of overweight and obesity) and exceeded pre-crisis levels by 2010 (52.9% prevalence). The population-wide increase in weight was immediately followed by a 116% increase in diabetes prevalence and 140% increase in diabetes incidence. Six years into the weight rebound phase, diabetes mortality increased by 49% (from 9.3 deaths per 10 000 people in 2002 to 13.9 deaths per 10 000 people in 2010). A deceleration in the rate of decline in mortality from coronary heart disease was also observed. In relation to the Cuban experience in 1980-2010, there is an association at the population level between weight reduction and death from diabetes and cardiovascular disease; the opposite effect on the diabetes and cardiovascular burden was seen on population-wide weight gain.

  20. Thyroid Cancer Incidence in New Jersey: Time Trend, Birth Cohort and Socioeconomic Status Analysis (1979–2006

    Directory of Open Access Journals (Sweden)

    Lisa M. Roche

    2011-01-01

    Full Text Available The study's purpose was to investigate thyroid cancer incidence time trends, birth cohort effects, and association with socioeconomic status (SES in New Jersey (NJ, a high incidence state, using NJ State Cancer Registry data. Thyroid cancer incidence rates in each sex, nearly all age groups, two major histologies and all stages significantly increased between 1979 and 2006. For each sex, age-specific incidence rates began greatly increasing in the 1924 birth cohort and, generally, the highest thyroid cancer incidence rate for each five-year age group occurred in the latest birth cohort and diagnosis period. Thyroid cancer incidence rates were significantly higher in NJ Census tracts with higher SES and in counties with a higher percentage of insured residents. These results support further investigation into the relationship between rising thyroid cancer incidence and increasing population exposure to medical (including diagnostic radiation, as well as widespread use of more sensitive diagnostic techniques.

  1. Modeling trends of health and health related indicators in Ethiopia (1995-2008: a time-series study

    Directory of Open Access Journals (Sweden)

    Nigatu Tilahun H

    2009-12-01

    Full Text Available Abstract Background The Federal Ministry of Health of Ethiopia has been publishing Health and Health related indicators of the country annually since 1987 E.C. These indicators have been of high importance in indicating the status of health in the country in those years. However, the trends/patterns of these indicators and the factors related to the trends have not yet been investigated in a systematic manner. In addition, there were minimal efforts to develop a model for predicting future values of Health and Health related indicators based on the current trend. Objectives The overall aim of this study was to analyze trends of and develop model for prediction of Health and Health related indicators. More specifically, it described the trends of Health and Health related indicators, identified determinants of mortality and morbidity indicators and developed model for predicting future values of MDG indicators. Methods This study was conducted on Health and Health related indicators of Ethiopia from the year 1987 E.C to 2000 E.C. Key indicators of Mortality and Morbidity, Health service coverage, Health systems resources, Demographic and socio-economic, and Risk factor indicators were extracted and analyzed. The trends in these indicators were established using trend analysis techniques. The determinants of the established trends were identified using ARIMA models in STATA. The trend-line equations were then used to predict future values of the indicators. Results Among the mortality indicators considered in this study, it was only Maternal Mortality Ratio that showed statistically significant decrement within the study period. The trends of Total Fertility Rate, physician per 100,000 population, skilled birth attendance and postnatal care coverage were found to have significant association with Maternal Mortality Ratio trend. There was a reversal of malaria parasite prevalence in 1999 E.C from Plasmodium Falciparum to Plasmodium Vivax. Based on

  2. Trends in the incidence of cancer in the black population of Harare, Zimbabwe 1991-2010.

    Science.gov (United States)

    Chokunonga, E; Borok, M Z; Chirenje, Z M; Nyakabau, A M; Parkin, D M

    2013-08-01

    Incidence rates of different cancers have been calculated for the black population of Harare, Zimbabwe for a 20-year period (1991-2010) coinciding with continuing social and lifestyle changes, and the peak, and subsequent wane, of the HIV-AIDS epidemic. The overall risk of cancer increased during the period in both sexes, with rates of cervix and prostate cancers showing particularly dramatic increases (3.3% and 6.4% annually, respectively). By 2004, prostate cancer had become the most common cancer of men. The incidence of cancer of the esophagus, formerly the most common cancer of men, has remained relatively constant, whereas rates of breast and cervix cancers, the most common malignancies of women, have shown significant increases (4.9% and 3.3% annually, respectively). The incidence of Kaposi sarcoma increased to a maximum around 1998-2000 and then declined in all age groups, and in both sexes The incidence of squamous cell cancers of the conjunctiva is relatively high, with temporal trends similar to those of Kaposi sarcoma. Non-Hodgkin lymphoma, the fifth most common cancer of men and fourth of women, showed a steady increase in incidence throughout the period (6.7-6.9% annually), although rates in young adults (15-39) have decreased since 2001. Cancer control in Zimbabwe, as elsewhere in sub-Saharan Africa, involves meeting the challenge of emerging cancers associated with westernization of lifestyles (large bowel, breast and prostate), while the incidence of cancers associated with poverty and infection (liver, cervix and esophagus) shows little decline, and the residual burden of the AIDS-associated cancers remains significant. Copyright © 2013 UICC.

  3. Association between the neighborhood obesogenic environment and colorectal cancer risk in the Multiethnic Cohort.

    Science.gov (United States)

    Canchola, Alison J; Shariff-Marco, Salma; Yang, Juan; Albright, Cheryl; Hertz, Andrew; Park, Song-Yi; Shvetsov, Yurii B; Monroe, Kristine R; Le Marchand, Loïc; Gomez, Scarlett Lin; Wilkens, Lynne R; Cheng, Iona

    2017-10-01

    Information on the role of the neighborhood environment and colorectal cancer risk is limited. We investigated the association between a comprehensive suite of possible obesogenic neighborhood attributes (socioeconomic status, population density, restaurant and retail food environments, numbers of recreational facilities and businesses, commute patterns, traffic density, and street connectivity) and colorectal cancer risk in the Multiethnic Cohort Study. Among 81,197 eligible participants living in California (35,397 males and 45,800 females), 1973 incident cases (981 males and 992 females) of invasive colorectal cancer were identified between 1993 and 2010. Separately for males and females, multivariable Cox regression models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for colorectal cancer risk overall and by racial/ethnic group (African American, Japanese American, Latino, white). In males, higher traffic density was associated with an increased risk of colorectal cancer (HR=1.29, 95% CI: 1.03-1.61, p=0.03, for quintile 5 vs. quintile 1; p-trend=0.06). While this association may be due to chance, this pattern was seen (albeit non-statistically significant) in all racial/ethnic groups except whites. There were no other significant associations between other neighborhood obesogenic attributes and colorectal cancer risk. Findings from our large racial/ethnically diverse cohort suggest neighborhood obesogenic characteristics are not strongly associated with the risk of colorectal cancer. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. La encuesta de presupuestos familiares 1973-74

    OpenAIRE

    Alonso-Colmenares, María Dolores; Lara, Ana; Ruiz-Castillo, Javier

    1991-01-01

    En este trabajo se describe la construcción y el contenido de una serie de ficheros sobre los gastos, los ingresos, el ahorro y las caracteristicas geognificas, demograficas y socioecon6micas de los hogares espaiioles residentes en viviendas familiares. La fuente de informaci6n es la Encuesta de Presupuestos F amiliares realizada por el INE en 1973-74

  5. Report of the Minister of Health on the activity carried out by the `Istituto Superiore di Sanita` (Italian National Institute of Health) in 1995 and 1996, according to art. 25 of the Law 7 August 1973, no. 519; Relazione del Ministro per la Sanita` sull`attivita` svolta dall`Istituto Superiore di Sanita` nel 1995 e 1996, ai sensi dell`art. 25 della Legge 7 agosto 1973, n. 519

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    The results of the activities carried out at the Istituto Superiore di Sanita` in the years 1995-1996 are presented. The report contains information on the structure of the Institute, the tasks entrusted to it by law, synthetic data on the researches carried out within the institutional projects and the projects financed by the Italian national health fund and the future perspectives. It also presents the list of scientific publications edited in 1995 and 1996, divided according to the institutional projects of research. [Italiano] Vengono riportati i risultati dell`attivita` svolta dall`Istituto Superiore di Sanita` negli anni 1995-1996. La relazione presenta informazioni sulla struttura dell`Istituto e sui compiti assegnatigli per legge e dati sintetici sull`attivita` di ricercasvoltanell`ambito dei progetti istituzionali e dei progetti finanziati sul Fondo sanitario nazionale e sulle prospettive future. Fornisce, inoltre, l`elenco delle pubblicazioni scientifiche, edite negli anni 1995 1 996, suddivise nell`ambito dei progetti di ricerca istituzionali.

  6. Oceanographic Station, temperature profiles, and other data from XBT and bottle casts from the DOLPHIN as part of the Marine Resources Monitoring, Assessment and Prediction (MARMAP) from 1973-02-12 to 1973-03-23 (NODC Accession 7300813)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Oceanographic Station,temperature profiles, and other data were collected from XBT and bottle casts from the DOLPHIN from 12 February 1973 to 23 March 1973. Data...

  7. Light at Night and Breast Cancer Risk Among California Teachers

    Science.gov (United States)

    Hurley, Susan; Goldberg, Debbie; Nelson, David; Hertz, Andrew; Horn-Ross, Pamela L.; Bernstein, Leslie; Reynolds, Peggy

    2014-01-01

    Background There is convincing evidence that circadian disruption mediated by exposure to light at night promotes mammary carcinogenesis in rodents. The role that light at night plays in human breast cancer etiology remains unknown. We evaluated the relationship between estimates of indoor and outdoor light at night and the risk of breast cancer among members of the California Teachers Study. Methods Indoor light-at-night estimates were based on questionnaire data regarding sleep habits and use of night time lighting while sleeping. Estimates of outdoor light at night were derived from imagery data obtained from the U.S. Defense Meteorological Satellite Program assigned to geocoded addresses of study participants. Analyses were conducted among 106,731 California Teachers Study members who lived in California, had no prior history of breast cancer, and provided information on lighting while sleeping. 5,095 cases of invasive breast cancer diagnosed 1995–2010 were identified via linkage to the California Cancer Registry. We used age-stratified Cox proportional hazard models to calculate hazard ratios (HRs) with 95% confidence intervals (CIs), adjusting for breast cancer risk factors and neighborhood urbanization and socioeconomic class. Results An increased risk was found for women living in areas with the highest quintile of outdoor light at night exposure estimates (HR=1.12 [95% CI=1.00 – 1.26], test for trend, P=0.06). While more pronounced among premenopausal women (HR=1.34 [95% CI=1.07 – 1.69], test for trend, P=0.04), the associations did not differ statistically by menopausal status (test for interaction, P=0.34). Conclusions Women living in areas with high levels of ambient light at night may be at an increased risk of breast cancer. Future studies that integrate quantitative measurements of indoor and outdoor light at night are warranted. PMID:25061924

  8. A fatal blow to Sunday driving in 1973

    DEFF Research Database (Denmark)

    Wagner, Michael

    2011-01-01

    The Yom Kippur war in October 1973 resulted in an oil embargo from OPEC (Organisation of Petroleum Exporting Countries) and as a consequence for eleven weekends it was strictly forbidden to drive on Sundays in Denmark –similar measures were taken in western Germany and the Netherlands. The ban...

  9. Shrinking Middle Class and Changing Income Distribution of Korea: 1995-2005

    OpenAIRE

    Joon-Woo Nahm

    2008-01-01

    This paper investigates the shrinking middle class hypothesis and reveals more details about recent trends in income distribution of Korea from 1995 to 2005. We find that the consensus view of a declining middle class is correct and the decline in the middle class splited equally into the lower class and the upper class in Korea. Furthermore, while the size and income share of the middle class declined, the share of the upper class increased rapidly and the share of the lower class remained s...

  10. Skin Cancer Trends

    Science.gov (United States)

    ... Children from the Sun? Are There Benefits to Spending Time Outdoors? The Surgeon General’s Call to Action to Prevent Skin Cancer Related Resources Sun Safety Tips for Men Tips for Families Tips for Schools Tips for Employers Tips for ...

  11. Tuberculosis en la Ciudad de la Habana, 1995-1999 Tuberculosis in Havana City, 1995-1999

    Directory of Open Access Journals (Sweden)

    José I Sevy Court

    2003-06-01

    indicators of the Cuban Tuberculosis Control Program. METHODS: Based on surveillance data from the Provincial Center of Hygiene and Epidemiology, the health care network and strategies of the tuberculosis control program were reviewed; incidence rates, case finding indicators, diagnosis and case management were described. RESULTS: Eight subjects with respiratory symptoms were found per 1,000 attending general medical care services. The incidence rates of all tuberculosis types declined from 16.4 in 1995 to 12.0 x 10(5 people in 1999. Pulmonary tuberculosis incidence rate was reduced from 15.1 in1995 to 10.4 x 10(5 in 1999, whereas extrapulmonary tuberculosis had an increment from 1.3 to 1.6 x 10(5 in the same period. Of all new cases, 40-50 % were diagnosed at multispecialty clinics, 67.6% were diagnosed by positive smears, 15.2 % by positive cultures, 13.8 % by clinical and X-rays evidences only; and 0.9 % and 1.5 % were respectively diagnosed by biopsy and necropsy. There was an increase in the incidence rate in the age group 15-64 years in 1996 and 1997 but it declined again in 1998 and 1999. The age group 64 years and over showed a rate reduction from 1995 to 1999. In general, incidence rates diminished in the overall period. The average delay between onset of symptoms and diagnosis improved from 42 days in 1995 to 28.6 days in 1999. CONCLUSIONS: There seems to be a halt in reporting trends of new cases in 1996. Tuberculosis indicators reveal satisfactory changes in the study period.

  12. Trends in breast, ovarian and cervical cancer incidence in Mumbai, India over a 30-year period, 1976–2005: an age–period–cohort analysis

    Science.gov (United States)

    Dhillon, P K; Yeole, B B; Dikshit, R; Kurkure, A P; Bray, F

    2011-01-01

    Background: Demographic, socioeconomic and cultural changes in India have increased longevity, delayed childbearing, decreased parity and resulted in a more westernised lifestyle, contributing to the increasing burden of cancer, especially among women. Methods: We evaluated secular changes in the incidence of breast, cervical and ovarian cancer in Mumbai women aged 30–64 between 1976 and 2005. Age-standardised incidence rates were calculated and presented by site and calendar period. An age–period–cohort (APC) analysis quantified recent time trends and the significance of birth cohort and calendar period effects. The estimated annual percent change (EAPC) was obtained from the drift parameter, expressing the linear time trend common to both calendar period and birth cohort. Results: Over the 30-year study period, the age-standardised rates significantly increased for breast cancer (EAPC: 1.1% (95% confidence interval (CI): 1.0, 1.3)), significantly decreased for cervical cancer (EAPC: −1.8% (95% CI: −2.0, −1.6)) and there was no statistically significant change for ovarian cancer (EAPC: 0.3% (95% CI: −0.1, 0.6)). For breast and cervical cancer, the best-fitting model was the APC model. Conclusions: The rates of breast, cervical and ovarian cancer remain low in comparison with western countries, and the divergent trends of breast (increasing) and cervical cancer (decreasing) in Mumbai were similar to those observed in several other Asian countries. The changing risk profile in successive generations – improved education, higher socioeconomic status, later age at marriage and at first child, and lower parity – may in combination partially explain the diverging generational changes in breast and cervical cancer in Mumbai in the last decades. PMID:21829198

  13. Environmental radioactivity in Canada 1973-1976

    International Nuclear Information System (INIS)

    1979-03-01

    The radiological surveillance program of the Department of National Health and Welfare is conducted for the purpose of determining levels of environmental radioactivity in Canada and assessing the resulting population exposures. This report summarizes the results obtained during 1973-1976 from the analyses of air, precipitation, water vapour, drinking water, milk, biota and bone for critical radionuclides. During this period, all radioactivity levels were below the maximum permissible limits recommended by the International Commission on Radiological Protection. (Auth)

  14. Trends in brain cancer mortality among U.S. Gulf War veterans: 21 year follow-up.

    Science.gov (United States)

    Barth, Shannon K; Dursa, Erin K; Bossarte, Robert M; Schneiderman, Aaron I

    2017-10-01

    Previous mortality studies of U.S. Gulf War veterans through 2000 and 2004 have shown an increased risk of brain cancer mortality among some deployed individuals. When veterans possibly exposed to environmental contaminants associated with demolition of the Khamisiyah Ammunition Storage Facility at Khamisiyah, Iraq, have been compared to contemporaneously deployed unexposed veterans, the results have suggested increased risk for mortality from brain cancer among the exposed. Brain cancer mortality risk in this cohort has not been updated since 2004. This study analyzes the risk for brain cancer mortality between 1991-2011 through two series of comparisons: U.S. Gulf War deployed and non-deployed veterans from the same era; and veterans possibly exposed to environmental contaminants at Khamisiyah compared to contemporaneously deployed but unexposed U.S. Gulf War veterans. Risk of brain cancer mortality was determined using logistic regression. Life test hazard models were created to plot comparisons of annual hazard rates. Joinpoint regression models were applied to assess trends in hazard rates for brain cancer mortality. U.S. Army veterans possibly exposed at Khamisiyah had similar rates of brain cancer mortality compared to those not possibly exposed; however, veterans possibly exposed had a higher risk of brain cancer in the time period immediately following the Gulf War. Results from these analyses suggest that veterans possibly exposed at Khamisiyah experienced different patterns of brain cancer mortality risk compared to the other groups. Published by Elsevier Ltd.

  15. Sowjetunion und Völkerrecht 1962-1973 / Henn-Jüri Uibopuu

    Index Scriptorium Estoniae

    Uibopuu, Henn-Jüri, 1929-2012

    1980-01-01

    Tutvustus: Sowjetunion und Völkerrecht 1962-1973 : Bibliographie und analyse / hrsg. Boris Meissner, Dietrich Frenzke und Erika Chilicki. Köln : Wissenschaft und Politik, 1979 [t.p. incorrectly: 1977

  16. Anal carcinoma in HIV-infected patients in the period 1995-2009

    DEFF Research Database (Denmark)

    Legarth, Rebecca; Helleberg, Marie; Kronborg, Gitte

    2013-01-01

    Abstract Background: Several studies have demonstrated an increased risk of non-AIDS cancers in HIV patients and, for some cancers, also in relatives of HIV patients. We aimed to estimate (1) the risk of anal carcinoma among HIV patients and their parents, and (2) the mortality after a diagnosis...... 1995-2009, and (2) parents of HIV patients compared with parents of controls for the period 1978-2009. Cancer diagnoses were identified from The Danish Cancer Registry. We further estimated the mortality rate ratios (MRR) of HIV patients compared with controls after the diagnosis of anal carcinoma....... Results: Thirty-six HIV patients versus 8 population controls were diagnosed with anal carcinoma. HIV patients had an increased risk of anal carcinoma (IRR 77.9, 95% CI 36.2-167.7), especially among men who have sex with men (MSM) (IRR 101.4, 95% CI 39.3-261.5). Fathers of HIV patients had an increased...

  17. A Decade of Never-smokers Among Lung Cancer Patients-Increasing Trend and Improved Survival.

    Science.gov (United States)

    Toh, Chee-Keong; Ong, Whee-Sze; Lim, Wan-Teck; Tan, Daniel Shao-Weng; Ng, Quan-Sing; Kanesvaran, Ravindran; Seow, Wei-Jie; Ang, Mei-Kim; Tan, Eng-Huat

    2018-03-17

    It is not known whether clinicopathologic characteristics, treatment, and survival of never-smokers among lung cancer incident cases have changed over time. We assessed the trend and overall survival (OS) of these patients within our institution during a 10-year period. We reviewed 2 cohorts of non-small-cell lung cancer patients with a diagnosis from 1999 to 2002 and from 2008 to 2011. The patient characteristics and OS were compared by smoking status within each cohort and between the 2 cohorts over time. Of the 992 patients in the 1999-2002 cohort and the 1318 patients in the 2008-2011 cohort, 902 and 1272 had a known smoking status, respectively. The proportion of never-smokers increased from 31% in 1999-2002 to 48% in 2008-2011 (P never-, former-, and current-smokers have remained largely constant over time. A greater proportion of never-smokers had Eastern Cooperative Oncology Group performance status 0 to 1 and adenocarcinoma. The median OS increased from 15.5 months in 1999-2002 to 24.9 months in 2008-2011 (P = .001) for never-smokers, 12.3 to 15.9 months (P = .150) for former-smokers, and 10.5 to 13.9 months (P = .011) for current-smokers. The larger survival improvement among never-smokers was likely accounted for by the larger increase in never-smokers who were treated with tyrosine kinase inhibitors and pemetrexed over time. We found an increasing trend of never-smokers among incident lung cancer cases and improved survival for these patients during a 10-year period. The documentation of smoking status in any national cancer registry is vital to estimate the true incidence of lung cancer among never-smokers over time. Copyright © 2018 Elsevier Inc. All rights reserved.

  18. Trends in RF-structure research

    International Nuclear Information System (INIS)

    Henke, H.

    1995-01-01

    New trends in RF structure research are presented. The choice is limited to developments as they are required by the next generation of light sources, particle factories and linear colliders. Therefore, emphasis is put on the suppression of higher order modes either in standing or travelling wave resonators and on the development of superconducting cavities. Finally, a brand new development of very high frequency structures with planar geometry suited for fabrication by lithography is mentioned. copyright 1995 American Institute of Physics

  19. Licensee contractor and vendor inspection status report. Quarterly report, January 1995--March 1995

    International Nuclear Information System (INIS)

    1995-05-01

    This periodical covers the results of inspections performed by the NRC's Special Inspection Branch, Vendor Inspection Section, that have been distributed to the inspected organizations during the period from January 1995 through March 1995

  20. The Changing Face of Noncardia Gastric Cancer Incidence Among US Non-Hispanic Whites.

    Science.gov (United States)

    Anderson, William F; Rabkin, Charles S; Turner, Natalie; Fraumeni, Joseph F; Rosenberg, Philip S; Camargo, M Constanza

    2018-01-19

    The initial step for noncardia gastric carcinogenesis is atrophic gastritis, driven by either Helicobacter pylori infection or autoimmunity. In recent decades, the prevalence rates of these two major causes declined and increased, respectively, with changes in Western lifestyles. We therefore assessed gastric cancer incidence trends for US race/ethnic groups, 1995-2013. Age-standardized rates (ASRs) from 45 North American Association of Central Cancer Tumor Registries were summarized by estimated annual percentage change (EAPC) and 95% confidence intervals (CIs). Age period cohort models supplemented standard descriptive techniques and projected future trends. There were 137 447 noncardia cancers in 4.4 billion person-years of observation. Among non-Hispanic whites, the ASR was 2.2 per 100 000 person-years, with an EAPC of -2.3% (95% CI = -2.0% to -2.6%). Notwithstanding this overall decline, EAPCs rose 1.3% (95% CI = 0.6% to 2.1%) for persons younger than age 50 years and fell -2.6% (95% CI = -2.4% to -2.9%) for older individuals. These converging trends manifested a birth cohort effect more pronounced among women than men, with incidence among women born in 1983 twofold (95% CI = 1.1-fold to 3.6-fold) greater than those born in 1951. Age interaction was also statistically significant among Hispanic whites, with slightly increasing vs decreasing EAPCs for younger and older individuals, respectively. Incidence declined regardless of age for other races. Current trends foreshadow expected reversals in both falling incidence and male predominance among non-Hispanic whites. Dysbiosis of the gastric microbiome associated with modern living conditions may be increasing risk of autoimmune gastritis and consequent noncardia cancer. The changing face by age and sex of gastric cancer warrants analytical studies to identify potential causal mechanisms. Published by Oxford University Press 2018. This work is written by US Government employees and is in the public

  1. Trends in esophageal cancer mortality in China during 1987-2009: age, period and birth cohort analyzes.

    Science.gov (United States)

    Guo, Pi; Li, Ke

    2012-04-01

    Esophageal cancer is one of the most commonly diagnosed malignant tumors in China. The aim of this study was to provide the representative and comprehensive informations about the long-term mortality trends of this disease in China between 1987 and 2009, using joinpoint regression and generalized additive models (GAMs). Age-standardized mortality rates (ASMR), overall and truncated (35-64 years), were calculated using the direct calculation method, and joinpoint regression was performed to obtain the estimated annual percentage changes (EAPC). GAMs were fitted to study the effects of age, period and birth cohort on mortality trends. ASMR exhibited an overall remarked decline for rural females (EAPC=-2.3 95%CI: -3.3, -1.2), urban males (EAPC=-1.8 95%CI: -2.6, -1.0) and urban females (EAPC=-3.7 95%CI: -4.9, -2.4), but a small drop observed was not statistically significant for rural males (EAPC=-0.9 95%CI: -2.0, 0.3). The declines in ASMR were more noticeable for urban residents in recent years. Among all the residents, age effect showed an progressively increasing trend, whereas cohort effect declined steadily after the year corresponding to the maximum risk value. Period effect seemed to remain substantially unchanged throughout the years. Although variations in mortality rates were observed according to sex and area, the overall decreasing trends in esophageal cancer mortality were found in most Chinese people, aside from rural males. The findings could correspond to the changes in age- and cohort-related factors in the population. Further study is required to understand these potential factors. Copyright © 2011 Elsevier Ltd. All rights reserved.

  2. Red and processed meat, nitrite, and heme iron intakes and postmenopausal breast cancer risk in the NIH-AARP Diet and Health Study

    Science.gov (United States)

    Inoue-Choi, Maki; Sinha, Rashmi; Gierach, Gretchen L.; Ward, Mary H.

    2015-01-01

    Previous studies have shown inconsistent associations between red and processed meat intake and breast cancer risk. N-nitroso compounds and heme iron have been hypothesized as contributing factors. We followed 193,742 postmenopausal women in the NIH-AARP Diet and Health Study and identified 9,305 incident breast cancers (1995–2006). Dietary intake was assessed using a food frequency questionnaire at baseline. We adjusted daily intakes of meat, nitrite, and heme iron for energy intake using the nutrient density method. We estimated multivariable-adjusted hazard ratios (HR) and 95% confidence intervals (CI) by quintiles of dietary exposures for all breast cancer, by stage (in-situ, localized, regional/distant), and by estrogen/progesterone receptor (ER/PR) status using Cox proportional hazards regression. Total red meat intake was positively associated with risk of regional/distant cancer (p-trend=0.02). The risk was 25% higher in the highest vs. lowest intake quintile (95%CI=1.03–1.52). Higher processed red meat intake (Q5 vs. Q1) was associated with 27% higher risk of localized breast cancer (95%CI=1.01–1.27, p-trend=0.03) and a 19% higher risk of regional/distant cancer (95%CI=0.98–1.44, p-trend=0.10). In addition, higher nitrite intake from processed red meat was positively associated with localized cancer (HR for Q5 vs. Q1=1.23, 95%CI=1.09–1.39, p-trendmeat and processed meat may increase risk of postmenopausal breast cancer. Added nitrite and heme iron may partly contribute to these observed associations. PMID:26505173

  3. Animal Investigation Program 1973 annual report: Nevada Test Site and vicinity

    International Nuclear Information System (INIS)

    Smith, D.D.; Giles, K.R.; Bernhardt, D.E.

    1977-05-01

    Data are presented from the radioanalysis of tissues collected from cattle, deer, desert bighorn sheep, and other wildlife that resided on or near the Nevada Test Site during 1973. Routine activities and special investigations are discussed. Iodine-131 was detected in the thyroid of a Nevada Test Site mule deer. The postulated source was worldwide fallout from a nuclear detonation conducted by the People's Republic of China. Other than the naturally occurring potassium-40, cesium-137 was the only gamma-emitting radionuclide detected with any consistency in soft tissues. Nine muscle samples from the Nevada Test Site beef herd contained levels of cesium-137 ranging from 14 to 50 pCi/kilogram. Muscle from two deer contained 20 and 30 pCi/kilogram. Rabbit muscle contained 200 pCi/kilogram and muscle from a feral horse contained 40 pCi/kilogram. Tritium levels in all animal tissues sampled were at background except for animals residing at the Area 15 farm and for a feral horse. Postulated sources of these exposures are discussed. The strontium content in bones continued the downward trend observed during recent years

  4. National Trends and Predictors of Locally Advanced Penile Cancer in the United States (1998-2012).

    Science.gov (United States)

    Chipollini, Juan; Chaing, Sharon; Peyton, Charles C; Sharma, Pranav; Kidd, Laura C; Giuliano, Anna R; Johnstone, Peter A; Spiess, Philippe E

    2017-08-12

    We analyzed the trends in presentation of squamous cell carcinoma (SCC) of the penis and determined the socioeconomic predictors for locally advanced (cT3-cT4) disease in the United States. The National Cancer Database was queried for patients with clinically nonmetastatic penile SCC and staging available from 1998 to 2012. Temporal trends per tumor stage were evaluated, and a multivariable logistic regression model was used to identify predictors for advanced presentation during the study period. A total of 5767 patients with stage ≤ T1-T2 (n = 5423) and T3-T4 (n = 344) disease were identified. Increasing trends were noted in all stages of penile SCC with a greater proportion of advanced cases over time (P = .001). Significant predictors of advanced presentation were age > 55 years, the presence of comorbidities, and Medicaid or no insurance (P guide targeted interventions in vulnerable populations. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Patterns and Trends of Liver Cancer Incidence Rates in Eastern and Southeastern Asian Countries (1983-2007) and Predictions to 2030.

    Science.gov (United States)

    Wu, Jie; Yang, Shigui; Xu, Kaijin; Ding, Cheng; Zhou, Yuqing; Fu, Xiaofang; Li, Yiping; Deng, Min; Wang, Chencheng; Liu, Xiaoxiao; Li, Lanjuan

    2018-05-01

    We examined temporal trends in liver cancer incidence rates overall and by histological type from 1983 through 2007. We predict trends in liver cancer incidence rates through 2030 for selected Eastern and Southeastern Asian countries. Data on yearly liver cancer incident cases by age group and sex were drawn from 6 major selected Eastern and Southeastern Asian countries or regions with cancer registries available in the CI5plus database, including China, Japan, Hong Kong Special Administrative Region (SAR), the Philippines, Singapore, and Thailand. We also analyzed data for the United States and Australia for comparative purposes. Age-standardized incidence rates were calculated and plotted from 1983 through 2007. Numbers of new cases and incidence rates were predicted through 2030 by fitting and extrapolating age-period-cohort models. The incidence rates of liver cancer have been decreasing, and decreases will continue in all selected Eastern and Southeastern Asian countries, except for Thailand, whose liver cancer incidence rate will increase due to the increasing incidence rate of intrahepatic cholangiocarcinomas. Even though the incidence rates of liver cancer are predicted to decrease in most Eastern and Southeastern Asian countries, the burden, in terms of new cases, will continue to increase because of population growth and aging. Based on an analysis of data from cancer registries from Asian countries, incidence rates of liver cancer are expected to decrease through 2030 in most Eastern and Southeastern Asian countries. However, in Thailand, the incidence rate of intrahepatic cholangiocarcinomas is predicted to increase, so health education programs are necessary. Copyright © 2018 AGA Institute. Published by Elsevier Inc. All rights reserved.

  6. Dietary pattern and breast cancer risk in Japanese women: the Japan Public Health Center-based Prospective Study (JPHC Study).

    Science.gov (United States)

    Shin, Sangah; Saito, Eiko; Inoue, Manami; Sawada, Norie; Ishihara, Junko; Takachi, Ribeka; Nanri, Akiko; Shimazu, Taichi; Yamaji, Taiki; Iwasaki, Motoki; Sasazuki, Shizuka; Tsugane, Shoichiro

    2016-05-28

    Evidence that diet is associated with breast cancer risk is inconsistent. Most of the studies have focused on risks associated with specific foods and nutrients, rather than overall diet. In this study, we aimed to evaluate the association between dietary patterns and breast cancer risk in Japanese women. A total of 49 552 Japanese women were followed-up from 1995 to 1998 (5-year follow-up survey) until the end of 2012 for an average of 14·6 years. During 725 534 person-years of follow-up, 718 cases of breast cancer were identified. We identified three dietary patterns (prudent, westernised and traditional Japanese). The westernised dietary pattern was associated with a 32 % increase in breast cancer risk (hazard ratios (HR) 1·32; 95 % CI 1·03, 1·70; P trend=0·04). In particular, subjects with extreme intake of the westernised diet (quintile (Q) Q5_5th) had an 83 % increase in risk of breast cancer in contrast to those in the lowest Q1 (HR 1·83; 95 % CI 1·25, 2·68; P trend=0·01). In analyses stratified by menopausal status, postmenopausal subjects in the highest quintile of the westernised dietary pattern had a 29 % increased risk of breast cancer (HR 1·29; 95 % CI 0·99, 1·76; P trend=0·04). With regard to hormone receptor status, the westernised dietary pattern was associated with an increased risk of oestrogen receptor-positive/progesterone receptor-positivetumours (HR 2·49; 95 % CI 1·40, 4·43; P trenddietary patterns were not associated with the risk of breast cancer in Japanese women. A westernised dietary pattern is associated with an increased risk of breast cancer in Japanese women.

  7. Temperature profile data collected using current meter, mooring, thermistor casts from the Atlantic Ocean in part of the International Decade of Ocean Exploration / Mid-Ocean Dynamics Experiment from 11 March 1973 to 01 July 1973 (NODC Accession 7700106)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature data were collected using current meter, mooring, thermistor casts from March 11, 1973 to July 1, 1973. Data were submitted by Woods Hole Oceanographic...

  8. Time trends for prostate cancer mortality in Brazil and its geographic regions: An age-period-cohort analysis.

    Science.gov (United States)

    Braga, Sonia Faria Mendes; de Souza, Mirian Carvalho; Cherchiglia, Mariangela Leal

    2017-10-01

    In the 1980s, an increase in mortality rates for prostate cancer was observed in North America and developed European countries. In the 1990s, however, mortality rates decreased for these countries, an outcome related to early detection of the disease. Conversely, an upward trend in mortality rates was observed in Brazil. This study describe the trends in mortality for prostate cancer in Brazil and geographic regions (North, Northeast, South, Southeast, and Central-West) between 1980 until 2014 and analyze the influence of age, period, and cohort effects on mortality rates. This time-series study used data from the Mortality Information System (SIM) and population data from Brazilian Institute for Geography and Statistics (IBGE). The effects on mortality rates were examined using age-period-cohort (APC) models. Crude and standardized mortality rates showed an upward trend for Brazil and its regions more than 2-fold the last 30 years. Age effects showed an increased risk of death in all regions. Period effects showed a higher risk of death in the finals periods for the North and Northeast. Cohort effects showed risk of death was higher for younger than older generations in Brazil and regions, mainly Northeast (RR Adjusted =3.12, 95% CI 1.29-1.41; RR Adjusted =0.28, 95% CI 0.26-0.30, respectively). The increase in prostate cancer mortality rates in Brazil and its regions was mainly due to population aging. The differences in mortality rates and APC effects between regions are related to demographic differences and access of health services across the country. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Cost-effectiveness research in cancer therapy: a systematic review of literature trends, methods and the influence of funding.

    Science.gov (United States)

    Al-Badriyeh, Daoud; Alameri, Marwah; Al-Okka, Randa

    2017-01-27

    To perform a first-time analysis of the cost-effectiveness (CE) literature on chemotherapies, of all types, in cancer, in terms of trends and change over time, including the influence of industry funding. Systematic review. A wide range of cancer-related research settings within healthcare, including health systems, hospitals and medical centres. All literature comparative CE research of drug-based cancer therapies in the period 1986 to 2015. Primary outcomes are the literature trends in relation to journal subject category, authorship, research design, data sources, funds and consultation involvement. An additional outcome measure is the association between industry funding and study outcomes. Descriptive statistics and the χ 2 , Fisher exact or Somer's D tests were used to perform non-parametric statistics, with a p value of research is presented to the practicing community, including in relation to journals, study designs, authorship and consultation, together with increased financial sponsorship by pharmaceutical industries, which may be more influencing study outcomes than other funding sources. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  10. Red meat intake may increase the risk of colon cancer in Japanese, a population with relatively low red meat consumption.

    Science.gov (United States)

    Takachi, Ribeka; Tsubono, Yoshitaka; Baba, Keisuke; Inoue, Manami; Sasazuki, Shizuka; Iwasaki, Motoki; Tsugane, Shoichiro

    2011-01-01

    Asian populations have changed from traditional to Westernized diets, with increased red meat intake. They are suggested to be particularly susceptible to the adverse effects of red meat on the development of colorectal cancers, however, few prospective studies of this putative link have been conducted. We examined associations between the consumption of red and processed meat and the risk of subsite-specific colorectal cancer by gender in a large Japanese cohort. During 1995-1998, a validated food frequency questionnaire was administered to 80,658 men and women aged 45-74 years. During 758,116 person-years of follow-up until the end of 2006, 1,145 cases of colorectal cancer were identified. Higher consumption of red meat was significantly associated with a higher risk of colon cancer among women [multivariate hazard ratios (95%CIs) for the highest versus lowest quintiles (HR): 1.48 (1.01, 2.17; trend p=0.03)], as was higher consumption of total meat among men [HR=1.44 (1.06, 1.98; trend p=0.07)]. By site, these positive associations were found for the risk of proximal colon cancer among women and for distal colon cancer among men. No association was found between the consumption of processed meat and risk of either colon or rectal cancer. In conclusion, red meat intake may modestly increase the risk of colon cancer in middle-aged Japanese, although the highest quintile of red meat consumption could be considered moderate by Western standards.

  11. Trends in colorectal cancer incidence: a period and birth-cohort analysis in a well-defined French population.

    Science.gov (United States)

    Chauvenet, Marion; Cottet, Vanessa; Lepage, Côme; Jooste, Valérie; Faivre, Jean; Bouvier, Anne-Marie

    2011-06-30

    France stands among high-risk areas for colorectal cancer. Different trends in CRC incidence are reported around the world. The aim of this study was to provide temporal trends in CRC incidence over a 30-year period in a French well-defined population. Between 1976 and 2005, 17,028 new cases were registered by the Burgundy digestive cancer registry. The mean variations in age-standardized incidence rates were estimated using a Poisson regression adjusted for age for each gender and location. The cumulative risk by birth cohort of developing a cancer over the age range 0-74 years was estimated using an age-cohort model. Incidence rates for right and left colon cancers increased more rapidly in males (respectively +11.7% and +10.3% on average by 5-year period) than in females (respectively +5.9% and +6.1%). It remained stable for sigmoid cancers in males (-0.1%) and decreased in females (-5.2%). It also decreased for rectal cancers both in males (-2.7%) and in females (-2.0%). The cumulative risk increased from 3.9% for males born around 1900 to 4.9% for those born around 1930 and then slightly decreased (4.5% among those born around 1950). It remained at the same level for females born around 1900 (2.7%) as for those born around 1930 (2.7%) and then slightly increased (2.9%) for those born around 1950. For right colon cancers, the cumulative risk increased strikingly in successive birth cohorts from 0.53% to 1.2% in males and 0.55% to 0.77% in females. The corresponding cumulative risks for the left colon were 0.24% and 0.42% in males and 0.14% and 0.29% in females. For sigmoid cancer, they decreased from 1.59% to 1.08% in males, and 0.88% to 0.80% in females. Temporal variations in incidence rates of colorectal cancers differed according to subsite, suggesting different aetiological factors and implications for diagnosis and screening strategies. Total colonoscopy must be the preferred strategy in high-risk groups or after a positive faecal occult blood test.

  12. Trends in colorectal cancer incidence: a period and birth-cohort analysis in a well-defined French population

    Directory of Open Access Journals (Sweden)

    Faivre Jean

    2011-06-01

    Full Text Available Abstract Background France stands among high-risk areas for colorectal cancer. Different trends in CRC incidence are reported around the world. The aim of this study was to provide temporal trends in CRC incidence over a 30-year period in a French well-defined population. Methods Between 1976 and 2005, 17,028 new cases were registered by the Burgundy digestive cancer registry. The mean variations in age-standardized incidence rates were estimated using a Poisson regression adjusted for age for each gender and location. The cumulative risk by birth cohort of developing a cancer over the age range 0-74 years was estimated using an age-cohort model. Results Incidence rates for right and left colon cancers increased more rapidly in males (respectively +11.7% and +10.3% on average by 5-year period than in females (respectively +5.9% and +6.1%. It remained stable for sigmoid cancers in males (-0.1% and decreased in females (-5.2%. It also decreased for rectal cancers both in males (-2.7% and in females (-2.0%. The cumulative risk increased from 3.9% for males born around 1900 to 4.9% for those born around 1930 and then slightly decreased (4.5% among those born around 1950. It remained at the same level for females born around 1900 (2.7% as for those born around 1930 (2.7% and then slightly increased (2.9% for those born around 1950. For right colon cancers, the cumulative risk increased strikingly in successive birth cohorts from 0.53% to 1.2% in males and 0.55% to 0.77% in females. The corresponding cumulative risks for the left colon were 0.24% and 0.42% in males and 0.14% and 0.29% in females. For sigmoid cancer, they decreased from 1.59% to 1.08% in males, and 0.88% to 0.80% in females. Conclusion Temporal variations in incidence rates of colorectal cancers differed according to subsite, suggesting different aetiological factors and implications for diagnosis and screening strategies. Total colonoscopy must be the preferred strategy in high

  13. Annual report of National Institute of Radiological Science, April 1995 -March 1996

    International Nuclear Information System (INIS)

    1997-03-01

    This annual report presents a brief summary of the research activities and the achievements in the Institute for fiscal year 1995 (from April 1995 to March 1996). The clinical trial of cancer therapy using heavy ion beams is making progress with successful results. Various kinds of basic researches using the same heavy ion beams are also growing up gradually in an open use system available to many researchers not only inside but also outside the Institute. Studies of newly assembled research groups are also going to appear. The Institute is covering a very wide area of comprehensive radiological sciences including physics, chemistry, biomedical sciences, clinical research and environmental science. The recent publications, list of keywords, author index, and organization and staff are included in this report. (M.N.)

  14. Annual report of National Institute of Radiological Science, April 1995 - March 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    This annual report presents a brief summary of the research activities and the achievements in the Institute for fiscal year 1995 (from April 1995 to March 1996). The clinical trial of cancer therapy using heavy ion beams is making progress with successful results. Various kinds of basic researches using the same heavy ion beams are also growing up gradually in an open use system available to many researchers not only inside but also outside the Institute. Studies of newly assembled research groups are also going to appear. The Institute is covering a very wide area of comprehensive radiological sciences including physics, chemistry, biomedical sciences, clinical research and environmental science. The recent publications, list of keywords, author index, and organization and staff are included in this report. (M.N.)

  15. Temperature and moisture regimes in the Enterprise Forest, 1970--1973

    International Nuclear Information System (INIS)

    Crow, T.R.; Buech, R.R.

    1977-01-01

    Within the Enterprise Radiation Forest, measurements of ambient air temperature, humidity, and precipitation were taken from 1970 through 1973. Temperature and moisture stresses that could alter the responses of organisms to gamma radiation were not evident during irradiation (1972) or during the recovery year 1973. Changes in microclimatic regimes as a result of the destruction of vegetation by gamma radiation were also assessed. Although differences in temperature and vapor-pressure deficit (VPD) were small when considering monthly means, mean maximum and mean minimum temperature and standardized plots of mean daily temperature and mean daily VPD indicated greater extremes in the newly created open environment than under the forest canopy. These relationships parallel those reported in comparisons of open environments to forested environments

  16. Longitudinal Trends in Anxiety, Depression, and Quality of Life During Different Intermittent Periods of Adjuvant Breast Cancer Chemotherapy.

    Science.gov (United States)

    Zhang, Jiayuan; Zhou, Yuqiu; Feng, Ziwei; Xu, Yong; Zeng, Guangchun

    Chemotherapy (CT) is an important adjuvant treatment that has been widely used for breast cancer (BC) patients. However, no research has focused on trends in emotions and quality of life (QOL) during intermittent periods between CT sessions that are critical for recovery. The aim of this study was to investigate longitudinal trends in anxiety, depression, and QOL during the different intermittent periods between adjuvant CT for BC. A longitudinal study design was adopted. Eighty-eight women undergoing CT for BC were selected using a purposive sampling method, and they completed the Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), and Functional Assessment of Cancer Therapy-Breast (FACT-B) at 5 points. A repeated-measures analysis-of-variance model was used to compare anxiety, depression, and QOL at different time points. The results showed a significant difference in SAS (F = 187.78, P fashion.

  17. Changing trends in the incidence (1999-2011 and mortality (1983-2013 of cervical cancer in the Republic of Korea

    Directory of Open Access Journals (Sweden)

    Yoon Park

    2015-05-01

    Full Text Available Cervical cancer is a well-known preventable cancer worldwide. Many countries including Korea have pursued the positive endpoint of a reduction in mortality from cervical cancer. Our aim is to examine changing trends in cervical cancer incidence and mortality after the implementation of a national preventive effort in Korea. Cervical cancer incidence data from 1999 to 2011 and mortality data from 1983 to 2013 were collected from the Korean Statistical Information Service. Yearly age-standardized rates (ASR per 100,000 were compared using two standards: the 2005 Korean population and the world standard population, based on Segi’s world standard for incidence and the World Health Organization for mortality. In Korea, the age-standardized incidence of cervical cancer per 100,000 persons declined from 17.2 in 2000 to 11.8 in 2011. However, the group aged 25 to 29 showed a higher rate in 2011 (ASR, 6.5 than in 2000 (ASR, 3.6. The age-standardized mortality rate per 100,000 persons dropped from 2.81 in 2000 to 1.95 in 2013. In the worldwide comparison, the incidence rates remained close to the average incidence estimate of more developed regions (ASR, 9.9. The decreasing mortality trend in Korea approached the lower rate observed in Australia (ASR, 1.4 in 2010. Although the incidence rate of cervical cancer is continuously declining in Korea, it is still high relative to other countries. Moreover, incidence and mortality rates in females aged 30 years or under have recently increased. It is necessary to develop effective policy to reduce both incidence and mortality, particularly in younger age groups.

  18. Innovations in health care and mortality trends from five cancers in seven European countries between 1970 and 2005.

    Science.gov (United States)

    Hoffmann, Rasmus; Plug, Iris; McKee, Martin; Khoshaba, Bernadette; Westerling, Ragnar; Looman, Caspar; Rey, Gregoire; Jougla, Eric; Lang, Katrin; Pärna, Kersti; Mackenbach, Johan P

    2014-04-01

    Although the contribution of health care to survival from cancer has been studied extensively, much less is known about its contribution to population health. We examine how medical innovations have influenced trends in cause-specific mortality at the national level. Based on literature reviews, we selected six innovations with proven effectiveness against cervical cancer, Hodgkin's disease, breast cancer, testicular cancer, and leukaemia. With data on the timing of innovations and cause-specific mortality (1970-2005) from seven European countries we identified associations between innovations and favourable changes in mortality. For none of the five specific cancers, sufficient evidence for an association between introduction of innovations and a positive change in mortality could be found. The highest association was found between the introduction of Tamoxifen and breast cancer mortality. The lack of evidence of health care effectiveness may be due to gradual improvements in treatment, to effects limited to certain age groups or cancer subtypes, and to contemporaneous changes in cancer incidence. Research on the impact of health care innovations on population health is limited by unreliable data on their introduction.

  19. Bucking the trend? Health care expenditures in low-income countries 1990-1995.

    Science.gov (United States)

    Jowett, M

    1999-01-01

    Health care expenditures in low-income countries are analysed for the years 1990 and 1995 using four key indicators. Key findings include a substantial reduction in public spending per capita across low-income countries between 1990-95; a significant shift towards private expenditures, which appears increasingly to be substituting rather than supplementing public expenditures; a fall in total and public health spending in many countries despite growth in national income, contradicting the relationship found in other studies. Two possible explanations are put forward. First that the patterns found are a direct result of the structural adjustment policies adopted by many low-income countries, which aim to control and often cut public financing, whilst promoting private health expenditures. Secondly, that following the wave of privatization of state industries, many governments are finding problems adapting to their new role as a tax collector, and are thus not benefiting from economic growth to the extent that might be expected.

  20. 1995 annual report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report presents the activities and accomplishments of Philippine Nuclear Research Institute (PNRI) for the fiscal year 1995. The highlights of the report are about the technology transfer, nuclear services, nuclear safety and research and development. Also, the special S and T events, list of 1995 IAEA contracts, experts missions, foreign travels of PNRI and non-PNRI personnel and the lists of technical papers are also included in this report.