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Sample records for cancer preliminary results

  1. Development of a distress inventory for cancer: preliminary results.

    Directory of Open Access Journals (Sweden)

    Thomas B

    2002-01-01

    Full Text Available CONTEXT: Advances in cancer treatment have led to cure and prolongation of patients′ lives; however associated psychosocial problems, including distress, can detrimentally affect patients′ compliance with treatment and ultimately, their outcome. Symptom distress has been well addressed in many studies; however, psychological distress has only been quantified by using depression or anxiety scales/checklists or quality of life scales containing a distress sub scale/component or by the use of scales that are not psychological distress-specific. AIMS: The present study is an attempt to construct a psychological distress inventory for specific use with cancer patients. SETTINGS AND DESIGN: The standardisation sample consisted of 63 randomly selected patients with head and neck cancer who had undergone/ were undergoing curative treatment at the Regional Cancer Centre, Trivandrum. PATIENTS AND METHODS: The Distress Inventory for Cancer contained 57 positively and negatively toned items. An item analysis was conducted, followed by a factor analysis, thereby identifying the domains influencing distress. RESULTS: The final questionnaire contained 26 items subdivided into four domains viz. the personal, spiritual, physical, and the family domains, with each domain providing a sub score. The reliability coefficient (Cronbach′s alpha of the scale was found to be 0.85. CONCLUSIONS: These are the preliminary results of an ongoing study on global distress and tool development process. Reported here is the first step towards development of such tool.

  2. Development of a distress inventory for cancer: preliminary results.

    OpenAIRE

    Thomas B; Mohan V; Thomas I; Pandey M

    2002-01-01

    CONTEXT: Advances in cancer treatment have led to cure and prolongation of patients′ lives; however associated psychosocial problems, including distress, can detrimentally affect patients′ compliance with treatment and ultimately, their outcome. Symptom distress has been well addressed in many studies; however, psychological distress has only been quantified by using depression or anxiety scales/checklists or quality of life scales containing a distress sub scale/component or by...

  3. Cancer Prevention Interdisciplinary Education Program at Purdue University: Overview and Preliminary Results

    Science.gov (United States)

    Teegarden, Dorothy; Lee, Ji-Yeon; Adedokun, Omolola; Childress, Amy; Parker, Loran Carleton; Burgess, Wilella; Nagel, Julie; Knapp, Deborah W.; Lelievre, Sophie; Agnew, Christopher R.; Shields, Cleveland; Leary, James; Adams, Robin; Jensen, Jakob D.

    2012-01-01

    Cancer prevention is a broad field that crosses many disciplines; therefore, educational efforts to enhance cancer prevention research focused on interdisciplinary approaches to the field are greatly needed. In order to hasten progress in cancer prevention research, the Cancer Prevention Internship Program (CPIP) at Purdue University was designed to develop and test an interdisciplinary curriculum for undergraduate and graduate students. The hypothesis was that course curriculum specific to introducing interdisciplinary concepts in cancer prevention would increase student interest in and ability to pursue advanced educational opportunities (e.g., graduate school, medical school). Preliminary results from the evaluation of the first year which included 10 undergraduate and 5 graduate students suggested that participation in CPIP is a positive professional development experience, leading to a significant increase in understanding of interdisciplinary research in cancer prevention. In its first year, the CPIP project has created a successful model for interdisciplinary education in cancer prevention research. PMID:21533583

  4. Breast-conserving surgery after neoadjuvant chemotherapy in patients with locally advanced cancer. Preliminary results

    OpenAIRE

    VERGINE, M.; SCIPIONI, P.; GARRITANO, S.; COLANGELO, M.; Di Paolo, A; LIVADOTI, G.; MATURO, A.; Monti, M

    2013-01-01

    Neoadjuvant chemotherapy (NACT) in locally advanced breast tumors may allow an adequate control of the disease impossible with surgery alone. Moreover, NACT increases the chance of breast-conserving surgery. Between 2008 and 2012, we treated with NACT 83 patients with locally advanced breast cancer. We report the preliminary results evaluating the impact of NACT on the type of surgery.

  5. The development of a telemedical cancer center within the Veterans Affairs Health Care System: a report of preliminary clinical results.

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    Billingsley, Kevin G; Schwartz, David L; Lentz, Susan; Vallières, Eric; Montgomery, R Bruce; Schubach, William; Penson, David; Yueh, Bevan; Chansky, Howard; Zink, Claudia; Parayno, Darla; Starkebaum, Gordon

    2002-01-01

    In order to optimize the delivery of multidisciplinary cancer care to veterans, our institution has developed a regional cancer center with a telemedical outreach program. The objectives of this report are to describe the organization and function of the telemedical cancer center and to report our early clinical results. The Veterans Affairs Health Care System is organized into a series of integrated service networks that serve veterans within different areas throughout the United States. Within Veterans Integrated Service Network 20 (Washington, Alaska, Idaho, Oregon) we have developed a regional cancer center with telemedicine links to four outlying facilities within the service area. The telemedical outreach effort functions through the use of a multidisciplinary telemedicine tumor board. The tumor board serves patients in outlying facilities by providing comprehensive, multidisciplinary consultation for the complete range of malignancies. For individuals who do require referral to the cancer center, the tumor board serves to coordinate the logistical and clinical details of the referral process. This program has been in existence for 1 year. During that time 85 patients have been evaluated in the telemedicine tumor board. Sixty-two percent of the patients were treated at their closest facility; 38% were referred to the cancer center for treatment and/or additional diagnostic studies. The patients' diagnoses included the entire clinical spectrum of malignant disease. Preliminary clinical results demonstrate the program is feasible and it improves access to multidisciplinary cancer care. Potential benefits include improved referral coordination and minimization of patient travel and treatment delays. PMID:12020412

  6. Preliminary Treatment Results of Intensity-Modulated Radiotherapy for Prostate Cancer

    OpenAIRE

    Kang-Hsing Fan; Yen-Chao Chen; Cheng-Keng Chuang; Min-Li Hsieh; Ji-Hong Hong

    2006-01-01

    Background: To review the initial treatment results of intensity-modulated radiotherapy(IMRT) for prostate cancer.Methods: Ninety-two patients treated with IMRT before July 2003 were included inthis study. The median follow-up was 32 months. The indications for IMRTincluded primary, adjuvant, and salvage treatment. Combined treatment withandrogen suppression therapy was variable. The primary study endpointswere chronic adverse events which were subjectively reported. Only patientswith an aden...

  7. Smoking cessation intervention within the framework of a lung cancer screening program: preliminary results and clinical perspectives from the "Cosmos-II" Trial.

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    Filippo, Lococo; Principe, Rosastella; Cesario, Alfredo; Apolone, Giovanni; Carleo, Francesco; Ialongo, Pasquale; Veronesi, Giulia; Cardillo, Giuseppe

    2015-02-01

    Data coming from the literature investigating the effectiveness and interaction between smoking cessation (SC) and lung cancer screening (LCScr) are still sparse and inconsistent. Herein, we report the preliminary results from the ongoing lung cancer screening trial ("Cosmos-II") focusing our analysis on the inter-relationship between the SC program and the LCScr.

  8. Impact of exposure to tobacco smoke, arsenic, and phthalates on locally advanced cervical cancer treatment—preliminary results

    Science.gov (United States)

    Bloom, Michael S.; Dumitrascu, Irina; Roba, Carmen A.; Pop, Cristian; Ordeanu, Claudia; Balacescu, Ovidiu; Gurzau, Eugen S.

    2016-01-01

    Background Cancer research is a national and international priority, with the efficiency and effectiveness of current anti-tumor therapies being one of the major challenges with which physicians are faced. Objective To assess the impact of exposure to tobacco smoke, arsenic, and phthalates on cervical cancer treatment. Methods We investigated 37 patients with locally advanced cervical carcinoma who underwent chemotherapy and radiotherapy. We determined cotinine and five phthalate metabolites in urine samples collected prior to cancer treatment, by gas chromatography coupled to mass spectrometry, and urinary total arsenic by atomic absorption spectrometry with hydride generation. We used linear regression to evaluate the effects of cotinine, arsenic, and phthalates on the change in tumor size after treatment, adjusted for confounding variables. Results We detected no significant associations between urinary cotinine, arsenic, or phthalate monoesters on change in tumor size after treatment, adjusted for urine creatinine, age, baseline tumor size, and cotinine (for arsenic and phthalates). However, higher %mono-ethylhexyl phthalate (%MEHP), a putative indicator of phthalate diester metabolism, was associated with a larger change in tumor size (β = 0.015, 95% CI [0.003–0.03], P = 0.019). Conclusion We found no statistically significant association between the urinary levels of arsenic, cotinine, and phthalates metabolites and the response to cervical cancer treatment as measured by the change in tumor size. Still, our results suggested that phthalates metabolism may be associated with response to treatment for locally advanced cervical cancer. However, these observations are preliminary and will require confirmation in a larger, more definitive investigation. PMID:27652000

  9. Proteomic Study of HPV-Positive Head and Neck Cancers: Preliminary Results

    Directory of Open Access Journals (Sweden)

    Géraldine Descamps

    2014-01-01

    Full Text Available Human papillomavirus (HPV was recently recognized as a new risk factor for head and neck squamous cell carcinoma. For oropharyngeal cancers, an HPV+ status is associated with better prognosis in a subgroup of nonsmokers and nondrinkers. However, HPV infection is also involved in the biology of head and neck carcinoma (HNC in patients with a history of tobacco use and/or alcohol consumption. Thus, the involvement of HPV infection in HN carcinogenesis remains unclear, and further studies are needed to identify and analyze HPV-specific pathways that are involved in this process. Using a quantitative proteomics-based approach, we compared the protein expression profiles of two HPV+ HNC cell lines and one HPV− HNC cell line. We identified 155 proteins that are differentially expressed (P<0.01 in these three lines. Among the identified proteins, prostate stem cell antigen (PSCA was upregulated and eukaryotic elongation factor 1 alpha (EEF1α was downregulated in the HPV+ cell lines. Immunofluorescence and western blotting analyses confirmed these results. Moreover, PSCA and EEF1α were differentially expressed in two clinical series of 50 HPV+ and 50 HPV− oral cavity carcinomas. Thus, our study reveals for the first time that PSCA and EEF1α are associated with the HPV-status, suggesting that these proteins could be involved in HPV-associated carcinogenesis.

  10. SBRT in unresectable advanced pancreatic cancer: preliminary results of a mono-institutional experience

    International Nuclear Information System (INIS)

    To assess the efficacy and safety of stereotactic body radiotherapy (SBRT) in patients with either unresectable locally advanced pancreatic adenocarcinoma or by locally recurrent disease after surgery. Between January 2010 and October 2011, 30 patients with unresectable or recurrent pancreatic adenocarcinoma underwent exclusive SBRT. Twenty-one patients (70%) presented with unresectable locally advanced disease and 9 patients (30%) showed local recurrence after surgery. No patients had metastatic disease. Gemcitabine-based chemotherapy was administered to all patients before SBRT. Prescription dose was 45Gy in 6 daily fractions of 7.5Gy. SBRT was delivered using the volumetric modulated arc therapy (VMAT) by RapidArc. Primary end-point of this study was freedom from local progression (FFLP), secondary end-points were overall survival (OS), progression free survival (PFS) and toxicity. Median Clinical Target Volume (CTV) was 25.6 cm3 (3.2-78.8 cm3) and median Planning Target Volume (PTV) was 70.9 cm3 (20.4- 205.2 cm3). The prescription dose was delivered in 25 patients (83%), in 5 patients (17%) it was reduced to 36Gy in 6 fractions not to exceed the dose constraints of organs at risk (OARs). Median follow-up was 11 months (2–28 months). FFLP was 91% at 6 months, 85% at median follow-up and 77% at 1 and 2 years. For the group with prescription dose of 45Gy, FFLP was 96% at 1 and 2 years. The median PFS was 8 months. The OS was 47% at 1 year and median OS was 11 months. At the end of the follow-up, 9 patients (32%) were alive and 4 (14%) were free from progression. No patients experienced G ≥ 3 acute toxicity. Our preliminary results show that SBRT can obtain a satisfactory local control rate for unresectable locally advanced and recurrent pancreatic adenocarcinoma. This fractionation schedule is feasible, and no G ≥ 3 toxicity was observed. SBRT is an effective emerging technique in the multi-modality treatment of locally advanced pancreatic tumors

  11. 3D freehand ultrasound for medical assistance in diagnosis and treatment of breast cancer: preliminary results

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    Torres, Fabian; Fanti, Zian; Arambula Cosío, F.

    2013-11-01

    Image-guided interventions allow the physician to have a better planning and visualization of a procedure. 3D freehand ultrasound is a non-invasive and low-cost imaging tool that can be used to assist medical procedures. This tool can be used in the diagnosis and treatment of breast cancer. There are common medical practices that involve large needles to obtain an accurate diagnosis and treatment of breast cancer. In this study we propose the use of 3D freehand ultrasound for planning and guiding such procedures as core needle biopsy and radiofrequency ablation. The proposed system will help the physician to identify the lesion area, using image-processing techniques in the 3D freehand ultrasound images, and guide the needle to this area using the information of position and orientation of the surgical tools. We think that this system can upgrade the accuracy and efficiency of these procedures.

  12. Dual-energy perfusion-CT in recurrent pancreatic cancer. Preliminary results

    International Nuclear Information System (INIS)

    To evaluate the diagnostic performance of dual energy (DE) perfusion-CT for the differentiation between postoperative soft-tissue formation and tumor recurrence in patients after potentially curative pancreatic cancer resection. 24 patients with postoperative soft-tissue formation in the conventional regular follow-up CT acquisition after pancreatic cancer resection with curative intent were included prospectively. They were examined with a 64-row dual-source CT using a dynamic sequence of 34 DE acquisitions every 1.5 s (80 ml of iodinated contrast material, 370 mg/ml, flow rate 5 ml/s). Weighted average (linearly blended M0.5) 120 kVp-equivalent dual-energy perfusion image data sets were evaluated with a body-perfusion CT tool for estimating blood flow, permeability, and blood volume. Diagnosis was confirmed by histological study (n=4) and by regular follow-up. Final diagnosis was local recurrence of pancreatic cancer in 15 patients and unspecific postoperative tissue formation in 9 patients. The blood-flow values for recurrence tissue trended to be lower compared to postoperative tissue formation with 16.6 ml/100 ml/min and 24.7 ml/100 ml/min, respectively for weighted average 120 kVp-equivalent image data, which was not significant (n.s.) (p=0.06, significance level 0.05). Permeability- and blood-volume values were only slightly lower in recurrence tissue (n.s.). DE perfusion-CT is feasible in patients after pancreatic cancer resection and a promising functional imaging technique. As only a trend for lower perfusion values in local recurrence compared to unspecific postoperative alterations was found, the perfusion differences are not yet sufficient to differentiate between malignancy and unspecific postoperative alterations for this new technique. Further studies and technical improvements are needed to generate reliable data for this clinically highly relevant differentiation.

  13. Dual-energy perfusion-CT in recurrent pancreatic cancer. Preliminary results

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    Fritz, F.; Skornitzke, S.; Kauczor, H.U.; Stiller, W.; Klauss, M. [Heidelberg Univ. (Germany). Clinic of Diagnostic and Interventional Radiology; Hackert, T. [Heidelberg Univ. (Germany). Clinic of Surgery; Grenacher, L. [Diagnostik Muenchen (Germany). Diagnostic Imaging Center

    2016-06-15

    To evaluate the diagnostic performance of dual energy (DE) perfusion-CT for the differentiation between postoperative soft-tissue formation and tumor recurrence in patients after potentially curative pancreatic cancer resection. 24 patients with postoperative soft-tissue formation in the conventional regular follow-up CT acquisition after pancreatic cancer resection with curative intent were included prospectively. They were examined with a 64-row dual-source CT using a dynamic sequence of 34 DE acquisitions every 1.5 s (80 ml of iodinated contrast material, 370 mg/ml, flow rate 5 ml/s). Weighted average (linearly blended M0.5) 120 kVp-equivalent dual-energy perfusion image data sets were evaluated with a body-perfusion CT tool for estimating blood flow, permeability, and blood volume. Diagnosis was confirmed by histological study (n=4) and by regular follow-up. Final diagnosis was local recurrence of pancreatic cancer in 15 patients and unspecific postoperative tissue formation in 9 patients. The blood-flow values for recurrence tissue trended to be lower compared to postoperative tissue formation with 16.6 ml/100 ml/min and 24.7 ml/100 ml/min, respectively for weighted average 120 kVp-equivalent image data, which was not significant (n.s.) (p=0.06, significance level 0.05). Permeability- and blood-volume values were only slightly lower in recurrence tissue (n.s.). DE perfusion-CT is feasible in patients after pancreatic cancer resection and a promising functional imaging technique. As only a trend for lower perfusion values in local recurrence compared to unspecific postoperative alterations was found, the perfusion differences are not yet sufficient to differentiate between malignancy and unspecific postoperative alterations for this new technique. Further studies and technical improvements are needed to generate reliable data for this clinically highly relevant differentiation.

  14. Preliminary results of the study about predictors of rectal side effects in radical radiotherapy of prostate cancer

    International Nuclear Information System (INIS)

    Objective: To analyze quantitatively and qualitatively the rectal side effect of radical radiotherapy applied to prostate cancer in patients treated at the National Cancer Institute (INCA) with three-dimensional external radiotherapy which the purposes is to determine predictions of this. Materials and Methods: From July 2008 to July 2010 98 patients were recruited, 63 of whom were followed up for 6 months. The gastrointestinal secondary effects occurred in different times of monitoring patients with RTOG / EORTC classifications (Radiation Therapy Oncology Group / European Organization for Research and Treatment of Cancer) and SOMA / LENT, is also used a questionnaire specifically constructed and validated by the cooperative Italian group . The results were correlated with clinical parameters (PSA, Gleason score, clinical T, risk class, hypertension and diabetes) and dosimetry (treatment volume, rectal volume, Total Dose, Dose Maximum rectum, mean dose to the rectum) to assess the correlation between them and the appearance of gastrointestinal secondary effects. Results: 27% and 28% patients experienced grade 1 and 2 RTOG rectal secondary effect at 1 and 3 months and 6 months the SOMA / LENT classification determined by 25%. Qualitatively altered intestinal transit is the most affected in these patients, it is having also found some relationship between the probability of occurrence of abnormal intestinal transit, and the tracking time passed. Conclusions: The rectal secondary effects is one of the major side effects both acute an chronic of the prostate radiotherapy, identify the determinants effects of the INCA patient population implies a substantial improvement in the quality of prostate cancer patients. Patients treated with radical radiotherapy for prostate cancer often have long survivals and consequently may suffer chronic effects of radiation therapy. We have verified the existence of secondary effects in the intestine but the results are very preliminary

  15. [Preoperative concurrent chemotherapy and radiation therapy in cervix cancer: preliminary results].

    Science.gov (United States)

    Kochbati, Lotfi; Ben Ammar, Chiraz Nasr; Benna, Farouk; Hechiche, Monia; Boussen, Hamouda; Besbes, Mounir; Ben Abdallah, Mansour; Rahal, Khaled; Ben Ayed, Farhat; Ben Romdhane, Khaked; Maalej, Mongi

    2005-03-01

    This is a retrospective study of patients treated for cervix cancer staged IB2, IIA or IIB with bulky tumor (> 4cm). Treatment was concurrent radiotherapy (45Gy with 1,8Gy daily fraction) and chemotherapy (5 cycles of Platinum 40mg/m2/week). All patients underwent Brachytherapy (15Gy on the reference isodose according to Paris system) followed by surgery (radical abdominal hysterectomy and bilateral pelvic lymphadenectomy: Piver 3) Between October 1999 and December 2002, forty five patients were treated in this protocol. Median age was 46 years (21- 68). Histology was squamous cell carcinoma in 93% and glandular carcinoma in 7%. Average external radiation dose was 44Gy (20-50). Ninety three percent of patients had at least 3 cycles of chemotherapy and 46,5% received the planned 5 cycles. On the operative specimens, there was 62,5% complete response and only 7 pelvic node involvement (17,5%). Four postoperative complications were noted (one vascular injury, one urinary fistula, one phlebitis and one lymph collection). Preoperative combined radiotherapy and chemotherapy in the early bulky stages of uterine cervix cancer is well tolerated and "gives" a high rate of sterilisation. There was no increase in surgical morbidity.

  16. Lung cancer risk and welding--preliminary results from an ongoing case-control study.

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    Jöckel, K H; Ahrens, W; Bolm-Audorff, U

    1994-06-01

    In a hospital-based case-control study, 391 male cases or primary lung cancer and the same number of controls--matched by sex, age, and region--were personally interviewed for their job and smoking histories. The data reported reflect the midpoint of a study aiming at a total of 1,000 cases. One objective of the study was to assess confounding by asbestos exposure in what was thought to be a welding-associated risk. While the odds ratios (OR) increased steeply with cumulative exposure to tobacco smoke and were raised also for lifelong asbestos exposure of over 4,100 working hours (OR = 1.91), the effect of welding exposure was reduced after adjustment for smoking and exposure to asbestos. Furthermore, no consistent dose-response relationship could be shown in relation to welding hours. Therefore the present study supports the hypothesis that some, if not all, of the excess risk of welders observed in the literature may be due to the exposure to asbestos. The finding that the subgroup of employees in the aircraft industry showed an increased odds ratio of 2.14 after adjustment for smoking and exposure to asbestos deserves further attention. This suggests the need for further research on the role of berryllium-containing alloys, which has been suggested by other authors.

  17. Clinical applications of total reflection X-Ray Fluorescence in the treatment of cancer, Preliminary results

    International Nuclear Information System (INIS)

    A simple procedure is presents in which direct irradiation of small (10 ?l) quantities of blood serum, without chemical treatment or internal standard addition, allows reliable quantification of the PT plasma level with a 300 ppb detection limit and precision of 7% (n=7) It is shown that the method allows determination of the time evolution of the drug concentration and the drug half life in the patient the results indicated the viability of an improvement in the clinical practice of chemotherapy by the routine analysis of platinum with total reflection X-Ray Fluorescence

  18. Percutaneous local ablation of unifocal subclinical breast cancer: clinical experience and preliminary results of cryotherapy

    International Nuclear Information System (INIS)

    To assess the ablative effectiveness, the oncological and cosmetic efficacy of image-guided percutaneous cryoablation in the treatment of single breast nodules with subclinical dimensions after identification with ultrasonography (US), mammography, magnetic resonance (MRI) and characterization by vacuum assisted biopsy. Fifteen women with a mean age of 73 ± 5 years (range 64-82 years) and lesion diameter of 8 ± 4 mm were undergoing cryotherapy technology with a single probe under US-guidance associated with intra-procedural lymph-node mapping and excision of the sentinel node. All the patients underwent surgical resection (lumpectomy) from 30 to 45 days after the percutaneous ablation. The iceball size generated by the cryoprobe during the procedure at minus 40 C was 16 x 41 mm. In 14 of the 15 patients was observed a complete necrosis of the cryo-ablated lesion both in post-procedural MRI follow-up and anatomo-pathological evaluation after surgical resection. In one case there was a residual disease in post-procedural MRI and postoperative histological examination, probably justified by an incorrect positioning of the probe. The percutaneous cryoablation as a ''minimally invasive'' technique can provide excellent oncological and cosmetic results on selected cases handled by experienced operators by using the tested devices. (orig.)

  19. Percutaneous local ablation of unifocal subclinical breast cancer: clinical experience and preliminary results of cryotherapy

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    Manenti, Guglielmo; Perretta, Tommaso; Gaspari, Eleonora; Pistolese, Chiara A.; Scarano, Lia; Cossu, Elsa; Simonetti, Giovanni; Masala, Salvatore [University Hospital ' ' Tor Vergata' ' , Department of Diagnostic Imaging and Interventional Radiology, Molecular Imaging and Radiotherapy, Rome (Italy); Bonanno, Elena [University Hospital ' ' Tor Vergata' ' , Department of Biopathology, Rome (Italy); Buonomo, Oreste C.; Petrella, Giuseppe [University Hospital ' ' Tor Vergata' ' , Department of General Surgery Division, Rome (Italy)

    2011-11-15

    To assess the ablative effectiveness, the oncological and cosmetic efficacy of image-guided percutaneous cryoablation in the treatment of single breast nodules with subclinical dimensions after identification with ultrasonography (US), mammography, magnetic resonance (MRI) and characterization by vacuum assisted biopsy. Fifteen women with a mean age of 73 {+-} 5 years (range 64-82 years) and lesion diameter of 8 {+-} 4 mm were undergoing cryotherapy technology with a single probe under US-guidance associated with intra-procedural lymph-node mapping and excision of the sentinel node. All the patients underwent surgical resection (lumpectomy) from 30 to 45 days after the percutaneous ablation. The iceball size generated by the cryoprobe during the procedure at minus 40 C was 16 x 41 mm. In 14 of the 15 patients was observed a complete necrosis of the cryo-ablated lesion both in post-procedural MRI follow-up and anatomo-pathological evaluation after surgical resection. In one case there was a residual disease in post-procedural MRI and postoperative histological examination, probably justified by an incorrect positioning of the probe. The percutaneous cryoablation as a ''minimally invasive'' technique can provide excellent oncological and cosmetic results on selected cases handled by experienced operators by using the tested devices. (orig.)

  20. Development and preliminary results of an in vivo Raman probe for early lung cancer detection

    Science.gov (United States)

    Short, Michael A.; Lam, Stephen; McWilliams, Annette; Zhao, Jianhua; Lui, Harvey; Zeng, Haishan

    2008-02-01

    Our previous results from Raman spectroscopy studies on ex vivo lung tissue showed the technique had great potential to differentiate between samples with different pathologies. In this work, a fast dispersive-type near-infrared (NIR) Raman spectroscopy system was developed to collect real-time, noninvasive, in vivo human lung spectra. The 785 nm excitation, and the collection of tissue emission were accomplished by using a reusable fiber optic catheter which passed down the instrument channel of a bronchoscope. Filters in two stages blocked laser emission other than 785 nm from reaching the tissue surface, and reduced fiber fluorescence and elastically scattered excitation light from being passed to the spectrometer. The spectrometer itself consisted of one of two holographic gratings with usable frequency ranges of: 700 to 2000 cm -1 and 1500 to 3400 cm -1. The dispersed light was detected by a cooled CCD array consisting of 400 by 1340 pixels. To increase the resolution of the system, while maximizing the throughput, a second fiber bundle, consisting of 54×100 μm diameter fibers connected the catheter to the spectrometer. The fibers in this second bundle were spread out to form a parabolic arc which replaced the conventional entrance slit. This geometry corrected for image aberrations, permitting complete CCD vertical binning, thereby yielding up to a 20-fold improvement in signal-to-noise ratio. The estimated spectral resolution of the system was 9 cm -1 for both gratings. So far we have measured spectra from 20 patients and have seen clear differences between spectra from tumor and normal tissue.

  1. High-b-Value Diffusion-Weighted Magnetic Resonance Imaging of Pancreatic Cancer and Mass-Forming Chronic Pancreatitis: Preliminary Results

    International Nuclear Information System (INIS)

    Background: Mass-forming chronic pancreatitis may mimic a pancreatic cancer on dynamic computed tomography (CT) and magnetic resonance (MR) imaging, and preoperative differential diagnosis is often difficult. Recently, the usefulness of diffusion-weighted MR imaging (DWI) in the diagnosis of pancreatic cancer has been reported in several studies. Purpose: To determine whether high-b-value DWI can distinguish pancreatic cancer from benign mass-forming chronic pancreatitis. Material and Methods: Twenty pancreatic cancers and four cases of mass-forming chronic pancreatitis were evaluated by high-b-value DWI (b=800 s/mm2). The signal intensity on DWI was visually evaluated, and the isotropic apparent diffusion coefficients (ADCs) were measured. Results: All twenty pancreatic cancers showed high signal intensity (18 showed very high, two showed slightly high) on DWI. None of the mass-forming chronic pancreatitis cases showed very high intensity (three showed iso to low, one showed slightly high) on DWI. The ADCs in the pancreatic cancer and mass-forming chronic pancreatitis were 1.38±0.32x10-3 mm2/s and 1.0 0.18x10-3 mm2/s, respectively (P<0.05). Conclusion: On high-b-value DWI, most pancreatic cancers showed very high signal intensity, and may hence be distinguished from benign mass-forming chronic pancreatitis based on our preliminary results

  2. Targeting breast cancer stem cells by dendritic cell vaccination in humanized mice with breast tumor: preliminary results

    Directory of Open Access Journals (Sweden)

    Pham PV

    2016-07-01

    Full Text Available Phuc Van Pham,1 Hanh Thi Le,1 Binh Thanh Vu,1 Viet Quoc Pham,1 Phong Minh Le,1 Nhan Lu-Chinh Phan,1 Ngu Van Trinh,1 Huyen Thi-Lam Nguyen,1 Sinh Truong Nguyen,1 Toan Linh Nguyen,2 Ngoc Kim Phan1 1Laboratory of Stem Cell Research and Application, University of Science, Vietnam National University, Ho Chi Minh City, 2Vietnam Military Medical University, Ha Dong, Ha Noi, Vietnam Background: Breast cancer (BC is one of the leading cancers in women. Recent progress has enabled BC to be cured with high efficiency. However, late detection or metastatic disease often renders the disease untreatable. Additionally, relapse is the main cause of death in BC patients. Breast cancer stem cells (BCSCs are considered to cause the development of BC and are thought to be responsible for metastasis and relapse. This study aimed to target BCSCs using dendritic cells (DCs to treat tumor-bearing humanized mice models. Materials and methods: NOD/SCID mice were used to produce the humanized mice by transplantation of human hematopoietic stem cells. Human BCSCs were injected into the mammary fat pad to produce BC humanized mice. Both hematopoietic stem cells and DCs were isolated from the human umbilical cord blood, and immature DCs were produced from cultured mononuclear cells. DCs were matured by BCSC-derived antigen incubation for 48 hours. Mature DCs were vaccinated to BC humanized mice with a dose of 106 cells/mice, and the survival percentage was monitored in both treated and untreated groups. Results: The results showed that DC vaccination could target BCSCs and reduce the tumor size and prolong survival. Conclusion: These results suggested that targeting BCSCs with DCs is a promising therapy for BC. Keywords: breast cancer, breast cancer stem cells, targeting cancer therapy, humanized mice, targeting cancer stem cells 

  3. Integrated PET/MRI for whole-body staging of patients with primary cervical cancer: preliminary results

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    Grueneisen, Johannes; Kinner, Sonja; Forsting, Michael; Lauenstein, Thomas; Umutlu, Lale [University Hospital Essen, University of Duisburg-Essen, Department of Diagnostic and Interventional Radiology and Neuroradiology, Essen (Germany); Schaarschmidt, Benedikt Michael [University Hospital Dusseldorf, University of Dusseldorf, Department of Diagnostic and Interventional Radiology, Dusseldorf (Germany); Heubner, Martin; Aktas, Bahriye [University Hospital Essen, University of Duisburg-Essen, Department of Obstetrics and Gynecology, Essen (Germany); Ruhlmann, Verena [University Hospital Essen, University of Duisburg-Essen, Department of Nuclear Medicine, Essen (Germany)

    2015-11-15

    To assess the diagnostic value of integrated PET/MRI for whole-body staging of cervical cancer patients, as well as to investigate a potential association between PET/MRI derived functional parameters and prognostic factors of cervical cancer. The present study was approved by the local institutional review board. Twenty-seven patients with histopathologically confirmed cervical cancer were prospectively enrolled in our study. All patients underwent a whole-body PET/MRI examination after written informed consent was obtained. Two radiologists separately evaluated the PET/MRI data sets regarding the determination of local tumor extent of primary cervical cancer lesions, as well as detection of nodal and distant metastases. Furthermore, SUV and ADC values of primary tumor lesions were analyzed and correlated with dedicated prognostic factors of cervical cancer. Results based on histopathology and cross-sectional imaging follow-up served as the reference standard. PET/MRI enabled the detection of all 27 primary tumor lesions of the uterine cervix and allowed for the correct determination of the T-stage in 23 (85 %) out of the 27 patients. Furthermore, the calculated sensitivity, specificity and diagnostic accuracy for the detection of nodal positive patients (n = 11) were 91 %, 94 % and 93 %, respectively. PET/MRI correctly identified regional metastatic disease (N1-stage) in 8/10 (80 %) patients and non-regional lymph node metastases in 5/5 (100 %) patients. In addition, quantitative analysis of PET and MRI derived functional parameters (SUV; ADC values) revealed a significant correlation with pathological grade and tumor size (p < 0.05). The present study demonstrates the high potential of integrated PET/MRI for the assessment of primary tumor and the detection of lymph node metastases in patients with cervical cancer. Providing additional prognostic information, PET/MRI may serve as a valuable diagnostic tool for cervical cancer patients in a pretreatment setting

  4. Targeting breast cancer stem cells by dendritic cell vaccination in humanized mice with breast tumor: preliminary results

    Science.gov (United States)

    Pham, Phuc Van; Le, Hanh Thi; Vu, Binh Thanh; Pham, Viet Quoc; Le, Phong Minh; Phan, Nhan Lu-Chinh; Trinh, Ngu Van; Nguyen, Huyen Thi-Lam; Nguyen, Sinh Truong; Nguyen, Toan Linh; Phan, Ngoc Kim

    2016-01-01

    Background Breast cancer (BC) is one of the leading cancers in women. Recent progress has enabled BC to be cured with high efficiency. However, late detection or metastatic disease often renders the disease untreatable. Additionally, relapse is the main cause of death in BC patients. Breast cancer stem cells (BCSCs) are considered to cause the development of BC and are thought to be responsible for metastasis and relapse. This study aimed to target BCSCs using dendritic cells (DCs) to treat tumor-bearing humanized mice models. Materials and methods NOD/SCID mice were used to produce the humanized mice by transplantation of human hematopoietic stem cells. Human BCSCs were injected into the mammary fat pad to produce BC humanized mice. Both hematopoietic stem cells and DCs were isolated from the human umbilical cord blood, and immature DCs were produced from cultured mononuclear cells. DCs were matured by BCSC-derived antigen incubation for 48 hours. Mature DCs were vaccinated to BC humanized mice with a dose of 106 cells/mice, and the survival percentage was monitored in both treated and untreated groups. Results The results showed that DC vaccination could target BCSCs and reduce the tumor size and prolong survival. Conclusion These results suggested that targeting BCSCs with DCs is a promising therapy for BC. PMID:27499638

  5. Quality of life in colon cancer patients with skin side effects: preliminary results from a monocentric cross sectional study

    Directory of Open Access Journals (Sweden)

    Meriggi Fausto

    2010-04-01

    Full Text Available Abstract Background Epidermal growth factor receptor inhibitors are widely prescribed anticancer drugs. Patients treated commonly develop dermatologic adverse drugs reactions, but rarely they are involved in systematic evaluation of their quality of life. This monocentric cross sectional study is carried out to assess quality of life in colon cancer patients experienced skin side effects due to anti epidermal growth factor receptor inhibitors therapy. Methods Consecutive patients with skin side effects to therapy treated at Fondazione Poliambulanza were enrolled in this study. Quality of life was evaluated with the Italian validated version of Skindex-29 questionnaire, exploring three dimensions: symptoms, emotional, and physical functioning. Skindex-29 was administered one time between the eighth and the twelfth week of the treatment. Results Forty-five consecutive patients, mainly with metastatic colon cancer (29 female, 16 male, with an average age of 59.31 years (ranging from 34-78 were included in the study and analyzed. Patients showed a great impact of skin side effects on symptoms (mean 43, followed by emotional (mean 30, and functioning (mean 26 scales. In general women, the 55-65 age class, and patients with partial remission reported the worst quality of life. Conclusions Epidermal growth factor receptor inhibitors' skin side effects have an important impact on quality of life in advanced colon cancer patients; symptoms scale is the most effect respect to emotional and functioning scales.

  6. DEPENDENCE OF YKL-40 mRNA TISSUE LEVELS ON KRAS MUTATION STATUS IN COLORECTAL CANCER - PRELIMINARY RESULTS

    Directory of Open Access Journals (Sweden)

    Yana Feodorova

    2015-08-01

    Full Text Available Colorectal cancer (CRC is one of the most deadly cancers worldwide. Despite the introduction of targeted molecular therapies in the last 10 years, overall survival has not increased substantially. CRC progression is accompanied by numerous genetic and epigenetic alterations and dysregulation of several signaling pathways, among which activation of Wnt and inactivation of TGF-β signaling. The molecular heterogeneity of CRC, however, hinders the molecular subtyping of CRC and thus the identification of common biomarkers for this pathology. The only three well established biomarkers for advanced-colorectal-cancer drug treatment are negative biomarkers. These are mutations in the genes KRAS, NRAS and BRAF which determine resistance to therapy with anti-EGFR antibodies. YKL-40 is a chitin-binding glycoprotein that has been shown to play a role in extracellular tissue remodeling, angiogenesis, cell migration and inflammation. Increased serum levels of this protein have been detected in patients with CRC but the role of YKL-40 in this neoplastic disease has not been studied extensively and the precise function of YKL-40 in CRC progression is not known. In the present study we determined the KRAS mutation status and measured the mRNA levels of YKL-40 of 24 patients with sporadic CRC. In addition, we assessed the association between these two parameters by statistical analysis. We are the first to show that in CRC YKL-40 mRNA levels are dependent on the presence of KRAS mutations, being prominently elevated in the wild type background. Our results indicate the potential role of YKL-40 as a target molecule for CRC therapy.

  7. Posttraumatic growth in women after breast cancer surgery – preliminary results from a study of Polish patients

    Directory of Open Access Journals (Sweden)

    Aleksandra Andysz

    2015-07-01

    Full Text Available Background The aim of the study was to answer the following research questions: What percentage of women after breast cancer surgery experienced posttraumatic growth (PTG? Which aspect of PTG was experienced to the greatest extent by the participants? Do age at the day of survey, age at diagnosis, time since diagnosis, type of surgery, non-surgical methods of treatment, participation in rehabilitation or physical activity significantly differentiate participants in PTG? Participants and procedure Forty-seven women after breast cancer surgery participated in the study. Posttraumatic growth was measured with the Polish version of the Posttraumatic Growth Inventory (PTGI consisting of 4 scales: Self-Perception (SP, Relating to Others (RO, Appreciation of Life (AL and Spiritual Change (SC. The demographic, disease and treatment related variables were controlled. Results Forty-three percent of participants experienced high, 23% moderate, and 34% little or no PTG. Posttraumatic growth manifested itself mainly positive changes in relationships with others. Age at the day of the survey did not correlate significantly with scores of PTGI. Age at diagnosis correlated significantly with total PTG (ρ = –0.37, p = .012, SP (ρ = –0.33, p = .029, RO (ρ = –0.40, p = .008 and AL (ρ = –0.39, p = .010. Women aged ≤ 50 at the day of the survey had significantly higher scores of AL than women > 50 (U = 117.50, p = .042. Women who were physically active at the day of the survey had significantly higher scores in total PTG (U = 118.50, p = .008, SP (U = 7.28, p = .007 and RO (U = 108.00, p = .003. Time since diagnosis, type of treatment and participation in rehabilitation after the surgery did not differentiate respondents significantly in PTG. Conclusions Posttraumatic growth was experienced by a considerable percentage of participants. The average level of PTG was moderate. Women physically active at the time of the survey showed higher levels of PTG

  8. Self-reported Cognitive Failure in Breast Cancer Survivors: Preliminary Results from a Danish Nationwide Cohort Study

    DEFF Research Database (Denmark)

    Amidi, Ali; Mehlsen, Mimi Yung; Zachariae, Robert;

    2012-01-01

    Purpose: Self-reported cognitive impairment after chemotherapy has instigated the colloquial use of the term “chemo-brain”. There is, however, uncertainty related to the cognitive impairments observed following cancer treatment, both in terms of the potential causes and long term status. The aim...... of the current study was to investigate: a) the long-term prevalence of self-reported cognitive failures in a large population based sample of breast cancer survivors, and, b) whether such reports differ between survivors treated with or without chemotherapy. Methods: Data originated from a large Danish...... nationwide cohort study including 3343 women treated for primary breast cancer. Follow-up data 7-10 years after initial surgery include questionnaires from 2061 recurrence-free breast cancer survivors (34-80 years). Of these, 870 (42.2%) had received chemotherapy. Self-reported cognitive failure was assessed...

  9. Preliminary Results of Noninvasive Detection of TMPRSS2:ERG Gene Fusion in a Cohort of Patients With Localized Prostate Cancer

    OpenAIRE

    Tavukcu, Hasan Huseyin; Mangir, Naside; Ozyurek, Mustafa; Turkeri, Levent

    2013-01-01

    Purpose The aim of this study was to evaluate TMPRSS2:ERG fusion rates in tissue, urine, blood, and pubic hair samples in a cohort of patients with localized prostate cancer and to correlate these findings with various clinicopathological parameters. Materials and Methods A cohort of 40 patients undergoing radical prostatectomy for localized prostate cancer (RRP group) and 10 control patients undergoing prostate biopsy were enrolled between 2006 and 2008. Urine, pubic hair, and peripheral blo...

  10. Preliminary results of concurrent chemotherapy and radiation therapy using high-dose-rate brachytherapy for cervical cancer

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyung Ja; Lee, Ji Hye; Lee, Re Na; Suh, Hyun Suk [Ewha Womans University College of Medicine, Seoul (Korea, Republic of)

    2006-09-15

    rate was 13% and distant metastatic rate was 3.3%. The crude rate of minor hematologic complications (RTOG grade 1-2) occurred in 3 patients (10%) and one patient had suffered from severe leukopenia (RTOG grade 4) during concurrent treatment. Acute minor enterocolitis (RTOG grade 1-2) occurred in 11 patients (37%) and one patient (3%) was suffered from colon perforation during radiation therapy. Late colitis of RTOG grade 1 occurred in 5 patients (15%). Acute cystitis of RTOG grade 1 occurred in 12 patients (40%) and late cystitis of RTOG grade 2 occurred in one patient (3%). No treatment related death was seen. The results of this study suggest that the concurrent chemoradiation therapy with HDR brachytherapy could be accepted as an effective and safe treatment for cervical cancer.

  11. EUPORIAS: plans and preliminary results

    Science.gov (United States)

    Buontempo, C.

    2013-12-01

    Recent advances in our understanding and ability to forecast climate variability have meant that skilful predictions are beginning to be routinely made on seasonal to decadal (s2d) timescales. Such forecasts have the potential to be of great value to a wide range of decision-making, where outcomes are strongly influenced by variations in the climate. In 2012 the European Commission funded EUPORIAS, a four year long project to develop prototype end-to-end climate impact prediction services operating on a seasonal to decadal timescale, and assess their value in informing decision-making. EUPORIAS commenced on 1 November 2012, coordinated by the UK Met Office leading a consortium of 24 organisations representing world-class European climate research and climate service centres, expertise in impacts assessments and seasonal predictions, two United Nations agencies, specialists in new media, and commercial companies in climate-vulnerable sectors such as energy, water and tourism. The poster describes the setup of the project, its main outcome and some of the very preliminary results.

  12. Preliminary results of ANAIS-25

    CERN Document Server

    Amaré, J; Cuesta, C; García, E; Ginestra, C; Martínez, M; Oliván, M A; Ortigoza, Y; de Solórzano, A Ortiz; Pobes, C; Puimedón, J; Sarsa, M L; Villar, P; Villar, J A

    2013-01-01

    The ANAIS (Annual Modulation with NaI(Tl) Scintillators) experiment aims at the confirmation of the DAMA/LIBRA signal using the same target and technique at the Canfranc Underground Laboratory. 250 kg of ultrapure NaI(Tl) crystals will be used as a target, divided into 20 modules, each coupled to two photomultipliers. Two NaI(Tl) crystals of 12.5 kg each, grown by Alpha Spectra from a powder having a potassium level under the limit of our analytical techniques, form the ANAIS-25 set-up. The background contributions are being carefully studied and preliminary results are presented: their natural potassium content in the bulk has been quantified, as well as the uranium and thorium radioactive chains presence in the bulk through the discrimination of the corresponding alpha events by PSA, and due to the fast commissioning, the contribution from cosmogenic activated isotopes is clearly identified and their decay observed along the first months of data taking. Following the procedures established with ANAIS-0 and ...

  13. Preliminary results of ANAIS-25

    Science.gov (United States)

    Amaré, J.; Cebrián, S.; Cuesta, C.; García, E.; Ginestra, C.; Martínez, M.; Oliván, M. A.; Ortigoza, Y.; Ortiz de Solórzano, A.; Pobes, C.; Puimedón, J.; Sarsa, M. L.; Villar, J. A.; Villar, P.

    2014-04-01

    The ANAIS (Annual Modulation with NaI(Tl) Scintillators) experiment aims at the confirmation of the DAMA/LIBRA signal using the same target and technique at the Canfranc Underground Laboratory. 250 kg of ultrapure NaI(Tl) crystals will be used as a target, divided into 20 modules, each coupled to two photomultipliers. Two NaI(Tl) crystals of 12.5 kg each, grown by Alpha Spectra from a powder having a potassium level under the limit of our analytical techniques, form the ANAIS-25 set-up. The background contributions are being carefully studied and preliminary results are presented: their natural potassium content in the bulk has been quantified, as well as the uranium and thorium radioactive chains presence in the bulk through the discrimination of the corresponding alpha events by PSA, and due to the fast commissioning, the contribution from cosmogenic activated isotopes is clearly identified and their decay observed along the first months of data taking. Following the procedures established with ANAIS-0 and previous prototypes, bulk NaI(Tl) scintillation events selection and light collection efficiency have been also studied in ANAIS-25.

  14. Stereotactic body radiotherapy for stage I lung cancer and small lung metastasis: evaluation of an immobilization system for suppression of respiratory tumor movement and preliminary results

    Directory of Open Access Journals (Sweden)

    Ayakawa Shiho

    2009-05-01

    Full Text Available Abstract Background In stereotactic body radiotherapy (SBRT for lung tumors, reducing tumor movement is necessary. In this study, we evaluated changes in tumor movement and percutaneous oxygen saturation (SpO2 levels, and preliminary clinical results of SBRT using the BodyFIX immobilization system. Methods Between 2004 and 2006, 53 consecutive patients were treated for 55 lesions; 42 were stage I non-small cell lung cancer (NSCLC, 10 were metastatic lung cancers, and 3 were local recurrences of NSCLC. Tumor movement was measured with fluoroscopy under breath holding, free breathing on a couch, and free breathing in the BodyFIX system. SpO2 levels were measured with a finger pulseoximeter under each condition. The delivered dose was 44, 48 or 52 Gy, depending on tumor diameter, in 4 fractions over 10 or 11 days. Results By using the BodyFIX system, respiratory tumor movements were significantly reduced compared with the free-breathing condition in both craniocaudal and lateral directions, although the amplitude of reduction in the craniocaudal direction was 3 mm or more in only 27% of the patients. The average SpO2 did not decrease by using the system. At 3 years, the local control rate was 80% for all lesions. Overall survival was 76%, cause-specific survival was 92%, and local progression-free survival was 76% at 3 years in primary NSCLC patients. Grade 2 radiation pneumonitis developed in 7 patients. Conclusion Respiratory tumor movement was modestly suppressed by the BodyFIX system, while the SpO2 level did not decrease. It was considered a simple and effective method for SBRT of lung tumors. Preliminary results were encouraging.

  15. Stereotactic body radiotherapy for stage I lung cancer and small lung metastasis: evaluation of an immobilization system for suppression of respiratory tumor movement and preliminary results

    International Nuclear Information System (INIS)

    In stereotactic body radiotherapy (SBRT) for lung tumors, reducing tumor movement is necessary. In this study, we evaluated changes in tumor movement and percutaneous oxygen saturation (SpO2) levels, and preliminary clinical results of SBRT using the BodyFIX immobilization system. Between 2004 and 2006, 53 consecutive patients were treated for 55 lesions; 42 were stage I non-small cell lung cancer (NSCLC), 10 were metastatic lung cancers, and 3 were local recurrences of NSCLC. Tumor movement was measured with fluoroscopy under breath holding, free breathing on a couch, and free breathing in the BodyFIX system. SpO2 levels were measured with a finger pulseoximeter under each condition. The delivered dose was 44, 48 or 52 Gy, depending on tumor diameter, in 4 fractions over 10 or 11 days. By using the BodyFIX system, respiratory tumor movements were significantly reduced compared with the free-breathing condition in both craniocaudal and lateral directions, although the amplitude of reduction in the craniocaudal direction was 3 mm or more in only 27% of the patients. The average SpO2 did not decrease by using the system. At 3 years, the local control rate was 80% for all lesions. Overall survival was 76%, cause-specific survival was 92%, and local progression-free survival was 76% at 3 years in primary NSCLC patients. Grade 2 radiation pneumonitis developed in 7 patients. Respiratory tumor movement was modestly suppressed by the BodyFIX system, while the SpO2 level did not decrease. It was considered a simple and effective method for SBRT of lung tumors. Preliminary results were encouraging

  16. Preliminary phase II results of selinexor, an oral selective inhibitor of nuclear export in patients with heavily pretreated gynecological cancers

    DEFF Research Database (Denmark)

    Vergote, Ignace; Lund, Bente; Havsteen, Hanne;

    2015-01-01

    stages of the disease. We here propose a randomized trial in order to demonstrate that resection of the primary tumour improves overall survival. METHODS/DESIGN: The CAIRO4 study is a multicentre, randomized, phase III study of the Dutch Colorectal Cancer Group (DCCG). Patients with synchronous...

  17. Quality of life in colon cancer patients with skin side effects: preliminary results from a monocentric cross sectional study

    OpenAIRE

    Meriggi Fausto; Rota Luigina; Braun Claudia; Mosconi Paola; Rizzi Anna; Andreis Federica; Mazzocchi Maria; Zaniboni Alberto

    2010-01-01

    Abstract Background Epidermal growth factor receptor inhibitors are widely prescribed anticancer drugs. Patients treated commonly develop dermatologic adverse drugs reactions, but rarely they are involved in systematic evaluation of their quality of life. This monocentric cross sectional study is carried out to assess quality of life in colon cancer patients experienced skin side effects due to anti epidermal growth factor receptor inhibitors therapy. Methods Consecutive patients with skin si...

  18. Preliminary Results Towards Contract Monitorability

    OpenAIRE

    Vella, Annalizz; Francalanza, Adrian

    2016-01-01

    This paper discusses preliminary investigations on the monitorability of contracts for web service descriptions. There are settings where servers do not guarantee statically whether they satisfy some specified contract, which forces the client (i.e., the entity interacting with the server) to perform dynamic checks. This scenario may be viewed as an instance of Runtime Verification, where a pertinent question is whether contracts can be monitored for adequately at runtime, otherwise stated as...

  19. Comparison of {sup 18}F-FACBC and {sup 11}C-choline PET/CT in patients with radically treated prostate cancer and biochemical relapse: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Nanni, Cristina; Boschi, Stefano [Azienda Ospedaliero-Universitaria di Bologna Policlinico S.Orsola-Malpighi, OU Nuclear Medicine, Bologna (Italy); Schiavina, Riccardo; Ambrosini, Valentina; Brunocilla, Eugenio; Martorana, Giuseppe; Fanti, Stefano [Azienda Ospedaliero-Universitaria di Bologna Policlinico S.Orsola-Malpighi, OU Urology, Bologna (Italy); Pettinato, Cinzia [Azienda Ospedaliero-Universitaria di Bologna Policlinico S.Orsola-Malpighi, OU Medical Physics, Bologna (Italy)

    2013-07-15

    We assessed the rate of detection rate of recurrent prostate cancer by PET/CT using anti-3-{sup 18}F-FACBC, a new synthetic amino acid, in comparison to that using {sup 11}C-choline as part of an ongoing prospective single-centre study. Included in the study were 15 patients with biochemical relapse after initial radical treatment of prostate cancer. All the patients underwent anti-3-{sup 18}F-FACBC PET/CT and {sup 11}C-choline PET/CT within a 7-day period. The detection rates using the two compounds were determined and the target-to-background ratios (TBR) of each lesion are reported. No adverse reactions to anti-3-{sup 18}F-FACBC PET/CT were noted. On a patient basis, {sup 11}C-choline PET/CT was positive in 3 patients and negative in 12 (detection rate 20 %), and anti-3-{sup 18}F-FACBC PET/CT was positive in 6 patients and negative in 9 (detection rate 40 %). On a lesion basis, {sup 11}C-choline detected 6 lesions (4 bone, 1 lymph node, 1 local relapse), and anti-3-{sup 18}F-FACBC detected 11 lesions (5 bone, 5 lymph node, 1 local relapse). All {sup 11}C-choline-positive lesions were also identified by anti-3-{sup 18}F-FACBC PET/CT. The TBR of anti-3-{sup 18}F-FACBC was greater than that of {sup 11}C-choline in 8/11 lesions, as were image quality and contrast. Our preliminary results indicate that anti-3-{sup 18}F-FACBC may be superior to {sup 11}C-choline for the identification of disease recurrence in the setting of biochemical failure. Further studies are required to assess efficacy of anti-3-{sup 18}F-FACBC in a larger series of prostate cancer patients. (orig.)

  20. Comparison of indium-111 octreotide and thalium-201 scintigraphy in patients mammographically suspected of having breast cancer: preliminary results

    International Nuclear Information System (INIS)

    Indium-111 octreotide and thallium-201 scintigraphic studies were compared in 21 patients (16 with palpable and five with non-palpable lesions) suspected of having breast malignancies on the basis of mammography. Early (15 min) and late (3 h) 201Tl (111 MBq) and 4-h and 24-h 111In-octreotide (111-148 MBq) static planar anterior images (matrix 256 x 256) were obtained on separate days. Images were evaluated both visually and quantitatively. Biopsy was performed following the imaging studies. Histopathology revealed 17 breast carcinomas (15 cases of invasive ductal carcinoma, one mucinous adenocarcinoma and one intraductal carcinoma) and four benign breast lesions (two fibroadenomas, one abscess and one case of fat necrosis). The means histopathological tumour size (mean largest diameter) was 3.38±1.9 cm. 111In-octreotide detected 16 of the 17 breast cancers (94%) while 201Tl detected 13 of them (76%). Both 111In-octreotide and 201Tl missed one nonpalpable carcinoma showing only an isolated cluster of microcalcifications on mammography. The smallest tumour size detected by both agents 1.5 x 1.5 cm. Of the four benign lesions, only the breast abscess revealed both 201Tl and 111In-octreotide uptake. 111In-octreotide scan also showed tracer uptake in five of the six patients with histologically proven axiallary metastases, while four of these six patient showed 201Tl uptake. (orig./VHE)

  1. Preliminary results of a phase I/II study of HDR brachytherapy alone for T1/T2 breast cancer

    International Nuclear Information System (INIS)

    Purpose: To investigate the feasibility, toxicity, cosmetic outcome, and local control of high-dose-rate (HDR) brachytherapy alone without whole breast external beam irradiation for early-stage breast carcinoma. Methods and Materials: Between June 1997 and August 1999, 32 women diagnosed with a total of 33 AJCC Stage I/II breast carcinomas underwent surgical breast excision and postoperative irradiation using HDR brachytherapy interstitial implantation as part of a multi-institutional clinical Phase I/II protocol. Eligible patients included those with T1, T2, N0, N1 (≤3 nodes positive), and M0 tumors of nonlobular histologic features with negative surgical margins, no extracapsular lymph node extension, and a negative postexcision mammogram. Brachytherapy catheters were placed at the initial excision, reexcision, or either sentinel or full-axillary sampling. Direct visualization, surgical clips, and ultrasound and/or CT scan assisted in the delineation of the target volume, defined as the excision cavity plus a 2-cm margin. High-activity 192Ir (3-10 Ci) was used to deliver 340 cGy/fraction, 2 fractions/d, for 5 consecutive days, to a total dose of 34 Gy to the target volume. Source position and dwell times were calculated using standard volume optimization techniques. Results: The median follow-up of all patients was 33 months, and the mean patient age was 63 years. The mean tumor size was 1.3 cm, and 55% had an extensive intraductal component. Three patients had positive axillary nodes. Two patients experienced moderate perioperative pain that required narcotic analgesics. No peri- or postoperative infections occurred. No wound healing problems and no significant skin reactions related to the implant developed. The Radiation Therapy Oncology Group late radiation morbidity scoring scheme was applied to the entire 33-case cohort. In the assessment of the skin, 30 cases were Grade 0-1 and 3 cases were Grade 2. Subcutaneous toxicity was scored as 11 patients with

  2. Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study

    DEFF Research Database (Denmark)

    Mitra, Anita V; Bancroft, Elizabeth K; Barbachano, Yolanda;

    2011-01-01

    Study Type - Diagnostic (validating cohort)
Level of Evidence 1b OBJECTIVES: To evaluate the role of targeted prostate cancer screening in men with BRCA1 or BRCA2 mutations, an international study, IMPACT (Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted screening ...

  3. Axitinib after Sunitinib in Metastatic Renal Cancer: Preliminary Results from Italian “Real-World” SAX Study

    Science.gov (United States)

    D'Aniello, Carmine; Vitale, Maria G.; Farnesi, Azzurra; Calvetti, Lorenzo; Laterza, Maria M.; Cavaliere, Carla; Della Pepa, Chiara; Conteduca, Vincenza; Crispo, Anna; De Vita, Ferdinando; Grillone, Francesco; Ricevuto, Enrico; De Tursi, Michele; De Vivo, Rocco; Di Napoli, Marilena; Cecere, Sabrina C.; Iovane, Gelsomina; Amore, Alfonso; Piscitelli, Raffaele; Quarto, Giuseppe; Pisconti, Salvatore; Ciliberto, Gennaro; Maiolino, Piera; Muto, Paolo; Perdonà, Sisto; Berretta, Massimiliano; Naglieri, Emanuele; Galli, Luca; Cartenì, Giacomo; De Giorgi, Ugo; Pignata, Sandro; Facchini, Gaetano; Rossetti, Sabrina

    2016-01-01

    Axitinib is an oral angiogenesis inhibitor, currently approved for treatment of metastatic renal cell carcinoma (mRCC) after failure of prior treatment with Sunitinib or cytokine. The present study is an Italian Multi-Institutional Retrospective Analysis that evaluated the outcomes of Axitinib, in second-line treatment of mRCC. The medical records of 62 patients treated with Axitinib, were retrospectively reviewed. The Progression Free Survival (PFS), the Overall Survival (OS), the Objective Response Rate (ORR), the Disease Control Rate (DCR), and the safety profile of axitinib and sunitinib–axitinib sequence, were the primary endpoint. The mPFS was 5.83 months (95% CI 3.93–7.73 months). When patients was stratified by Heng score, mPFS was 5.73, 5.83, 10.03 months according to poor, intermediate, and favorable risk group, respectively. The mOS from the start of axitinib was 13.3 months (95% CI 8.6–17.9 months); the observed ORR and DCR were 25 and 71%, respectively. When stratified patients by subgroups defined by duration of prior therapy with Sunitinib (≤ vs. >median duration), there was a statistically significant difference in mPFS with 8.9 (95% CI 4.39–13.40 months) vs. 5.46 months (95% CI 4.04–6.88 months) for patients with a median duration of Sunitinib >13.2 months. DCR and ORR to previous Sunitinib treatment was associated with longer statistically mPFS, 7.23 (95% CI 3.95–10.51 months, p = 0.01) and 8.67 (95% CI 4.0–13.33 months, p = 0.008) vs. 2.97 (95% CI 0.65–5.27 months, p = 0.01) and 2.97 months (95% CI 0.66–5.28 months, p = 0.01), respectively. Overall Axitinib at standard schedule of 5 mg bid, was well-tolerated. The most common adverse events of all grades were fatig (25.6%), hypertension (22.6%), gastro-intestinal disorders (25.9%), and hypothyroidism (16.1%). The sequence Sunitinib–Axitinib was well-tolerated without worsening in side effects, with a median OS of 34.7 months (95% CI 18.4–51.0 months). Our results are

  4. Dynamic contrast-enhanced computed tomography as a potential biomarker in patients with metastatic renal cell carcinoma: preliminary results from the Danish Renal Cancer Group Study-1

    DEFF Research Database (Denmark)

    Mains, Jill Rachel; Donskov, Frede; Pedersen, Erik Morre;

    2014-01-01

    OBJECTIVES: The aim of this study was to explore the impact of dynamic contrast-enhanced (DCE) computer tomography (CT) as a biomarker in metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS: Twelve patients with favorable or intermediate Memorial Sloan Kettering Cancer Center risk group...... and clear cell mRCC participating in an ongoing prospective randomized phase II trial comprising interleukin-2-based immunotherapy and bevacizumab were included in this preliminary analysis. All patients had a follow-up time of at least 2 years. Interpretation of DCE-CT (max slope method) was...

  5. Conformal radiotherapy to 76 Gy in localized prostate cancer. Therapeutic modalities and preliminary results; Radiotherapie conformationnelle a 76 Gy des cancers localises de la prostate. Modalites therapeutiques et resultats preliminaires

    Energy Technology Data Exchange (ETDEWEB)

    Pontvert, D.; Mammar, H. [Institut Curie, Dept. d' Oncologie Radiotherapique, 75 - Paris (France); Flam, T.; Debre, B. [Hopital Cochin-Saint-Vincent-de-Paul, Service d' Urologie, 75 - Paris (France); Thiounn, N. [Hopital Necker-Enfants-Malades, Service d' Urologie, 75 - Paris (France); Gaboriaud, G. [Institut Curie, Service de Physique Medicale, 75 - Paris (France); Jourdan-Da Silvae, N. [Institut Curie, Service de Biostatistique et d' evaluation clinique, 75 - Paris (France); Beuzeboc, P. [Institut Curie, Dept. d' Oncologie Medicale, 75 - Paris (France)

    2008-03-15

    Purpose: to describe therapeutic modalities for localized prostate cancer treated by conformal radiation to 76 Gy with or without androgen ablation. To evaluate the preliminary results in terms of survival, biological control and toxicity. Patients and method: between January 1998 and June 2001, 321 patients with localized prostate cancer were irradiated at Institut Curie. Tumors were stratified into the three Memorial Sloan-Kettering Cancer Center prognostic groups (1998) for analysis: favorable risk group (F.G.) 23%, intermediate risk group (I.G.) 36.5%, unfavorable risk group (U.G.) 40.5%. Androgen deprivation, mainly neo-adjuvant, less or equal to one year was prescribed to 93.8% of patients (72.6% less or equal to six months). Planning target volume prescription doses were: prostate: 76 Gy, seminal vesicles: 56 to 76 Gy, and pelvic lymph nodes: 44 Gy to 16.8% of patients. Results: the five-year actuarial overall survival was 94% (95% I.C.: 90-97%). The median post-therapeutic follow-up was 36 months (nine to 60 months). The 48-month actuarial rates of biochemical control for the three prognostic groups were statistically different according to both the American Society for Therapeutic Radiology and Oncology consensus (A.S.T.R.O. 1997) and the Fox Chase Cancer Center definitions of biochemical failure (F.C.C.C. 2000) with respectively 87 and 94% for F.G., 78 and 84% for I.G., 54 and 58% for U.G. (P < 10-6 and P < 10-8). At time of our analysis, late post-treatment rectal and bladder bleedings were 17,4 and 13,6%, respectively. According to a 1-4 scale adapted from M.D. Anderson Cancer Center criteria: rectal bleedings were grade 1 (9.6%), grade 2 (6.2%) and grade 3 (1.6%). Bladder bleedings were grade 2 (13%) and grade 3 (0.6%). Analysis of rectal bleeding risk factors showed significant correlations with pelvic lymph nodes irradiation for grade 2 and 3, (P = 0.02), and for all grades, a correlation with smaller rectal wall volumes (P = 0.03), and greater

  6. Rare earth optogalvanic spectroscopy: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Destro, Marcelo G.; Neri, Jose W.; Rodrigues, Nicolau A.S.; Silveira, Carlos A.B.; Riva, Rudimar [Instituto de Estudos Avancados (IEAv/EFO), Sao Jose dos Campos, SP (Brazil). Div. de Fotonica]. E-mail: destro@ieav.cta.br; Victor, Alessandro R. [Instituto Tecnologico de Aeronautica (ITA), Sao Jose dos Campos, SP (Brazil)

    2008-07-01

    The IEAv has special interest in the studies of rare earth isotope applications in laser medium and integrated optics as well as aerospace research. We are starting to work with Ytterbium, Erbium, Dysprosium and Neodymium laser selective photoionization research. This paper describes the preliminary results of emission and optogalvanic spectroscopy obtained from a Neodymium hollow cathode lamps. Furthermore these results were used to setup our laser systems to work to leads a Nd isotopes selective laser photoionization. (author)

  7. Rare earth optogalvanic spectroscopy: preliminary results

    International Nuclear Information System (INIS)

    The IEAv has special interest in the studies of rare earth isotope applications in laser medium and integrated optics as well as aerospace research. We are starting to work with Ytterbium, Erbium, Dysprosium and Neodymium laser selective photoionization research. This paper describes the preliminary results of emission and optogalvanic spectroscopy obtained from a Neodymium hollow cathode lamps. Furthermore these results were used to setup our laser systems to work to leads a Nd isotopes selective laser photoionization. (author)

  8. Preliminary results in surgery of Parkinson's disease.

    Science.gov (United States)

    Nasser, J A; Confort, C I; Ferraz, A; Bouza, A A

    1998-09-01

    The authors present the preliminary results of 20 patients selected to be operated on between January 1996 and April 1997. These patients presented one of the present indications for stereotactic posteroventral pallidotomy (PVP), such as: rigidity, akinesia/bradykinesia, gait dysfunction, drug induced dyskinesias and tremor. Every patient of this protocol was evaluated by: UPDRS score, Schwab and England scale, Hoehn and Yahr Staging Scale before and after surgery. The results in 3 months showed a remarkable improvement after PVP (P < 0.01) in all functional assessments, except for facial expression, speech and posture. The morbidity was 5%. 5 patients (25%) who were in Hoehn and Yahr 5 underwent a bilateral simultaneous PVP. In 5 patients (25%), who had tremor, during the PVP, VIM thalamotomy was added. These preliminary results, suggest that PVP is highly effective for PD symptoms. PMID:9850746

  9. Preliminary results in surgery of Parkinson's disease

    Directory of Open Access Journals (Sweden)

    NASSER JOSÉ AUGUSTO

    1998-01-01

    Full Text Available The authors present the preliminary results of 20 patients selected to be operated on between January 1996 and April 1997. These patients presented one of the present indications for stereotactic postero-ventral pallidotomy (PVP, such as: rigidity, akinesia/bradykinesia, gait dysfunction, drug induced dyskinesias and tremor. Every patient of this protocol was evaluated by: UPDRS score, Schwab and England scale, Hoehn and Yahr Staging Scale before and after surgery. The results in 3 months showed a remarkable improvement after PVP (P<0.01 in all functional assessments, except for facial expression, speech and posture. The morbidity was 5%. 5 patients (25% who were in Hoehn and Yahr 5 underwent a bilateral simultaneous PVP. In 5 patients (25%, who had tremor, during the PVP, VIM thalamotomy was added. These preliminary results suggest that PVP is highly effective for PD symptoms

  10. Preliminary results in surgery of Parkinson's disease.

    Science.gov (United States)

    Nasser, J A; Confort, C I; Ferraz, A; Bouza, A A

    1998-09-01

    The authors present the preliminary results of 20 patients selected to be operated on between January 1996 and April 1997. These patients presented one of the present indications for stereotactic posteroventral pallidotomy (PVP), such as: rigidity, akinesia/bradykinesia, gait dysfunction, drug induced dyskinesias and tremor. Every patient of this protocol was evaluated by: UPDRS score, Schwab and England scale, Hoehn and Yahr Staging Scale before and after surgery. The results in 3 months showed a remarkable improvement after PVP (P < 0.01) in all functional assessments, except for facial expression, speech and posture. The morbidity was 5%. 5 patients (25%) who were in Hoehn and Yahr 5 underwent a bilateral simultaneous PVP. In 5 patients (25%), who had tremor, during the PVP, VIM thalamotomy was added. These preliminary results, suggest that PVP is highly effective for PD symptoms.

  11. Correlation between apparent diffusion coefficients and standardized uptake values in hybrid {sup 18}F-FDG PET/MR: Preliminary results in rectal cancer

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Ju Hye [Dept. of Nuclear Medicine, Kyungpook National University Hospital, Daegu (Korea, Republic of); Cho, Ihn Ho; Chun, Kyung Ah; Kong, Eun Jung; Kwon, Sang Don; Kim, Jae Hwang [Yeungnam University Hospital, Daegu (Korea, Republic of)

    2016-06-15

    Fluorine-18-fluorodeoxyglucose ({sup 18}F-FDG) positron emission tomography (PET) and diffusion-weighted magnetic resonance imaging (DWI) share the same role in clinical oncology and it is feasible to obtain the standardized uptake value (SUV) and apparent diffusion coefficient (ADC) simultaneously by emerging the hybrid positron emission tomography/magnetic resonance (PET/MR). This study investigated the correlation between the ADCs of rectal cancer lesions and their SUVs derived from hybrid PET/MR. Nine patients with histologically proven rectal adenocarcinoma (5 men, 4 women; mean age, 70 ± 15.91 years) underwent torso {sup 18}F-FDG PET/CT and regional hybrid {sup 18}F-FDG PET/MR sequentially. A fixed threshold value of 40 % of maximum uptake was used to determine tumor volume of interest (VOI) on PET image; SUV{sub max}, SUV{sub peak}, and SUV{sub mean} were calculated automatically. A single freehand region of interest (ROI) was drawn on high b-value (b1000) DWI image and copied to corresponding ADC map to determine the ADCmean of rectal cancer lesion. Spearman'rank correlation coefficient (ρ) was calculated to determine the correlation between SUVs and ADC values. SUV{sub max}, SUV{sub peak}, and SUV{sub mean} derived by hybrid PET/MR were 12.35 ± 4.66 (mean ± standard deviation), 9.66  ± 3.15 and 7.41 ± 2.54, respectively. The ADCmean value of rectal cancer lesions was 1.02 ± 0.08 × 10{sup -3}mm{sup 2}/s. ADCmean was significantly and inversely correlated with SUV values (SUV{sub max}, ρ = -0.95, p < 0.001; SUV{sub peak}, ρ = -0.93, p < 0.001; SUV{sub mean}, ρ = -0.91, p = 0.001). This preliminary hybrid PET/MR study demonstrates a significant inverse correlation exists between metabolic activity on {sup 18}F-FDG PET and water diffusion on DWI in rectal cancer.

  12. Primary radiotherapy after tumour excision as an alternative to mastectomy for early breast cancer. Rationale and preliminary results of a prospective study.

    Science.gov (United States)

    Browde, S; Nissenbaum, M M

    1983-09-28

    A conservative approach to the management of breast cancer is gaining acceptance. The evidence from many retrospective and prospective studies indicates that breast-preserving surgery and radiation therapy give results equal to those of mastectomy. Relapse affecting the breast alone has been shown not to be detrimental to survival, while the psychological benefits to the patients have been gratifying. A prospective study of early breast cancer treated by conservative surgery and radiation was commenced at the Johannesburg Hospital in 1980. The results in 57 patients are reported. So far there have been 2 cases of local recurrence. In the majority of cases satisfactory cosmetic results were achieved. It is considered that lumpectomy with axillary dissection to establish nodal status followed by irradiation is the treatment of choice for stage I and II carcinoma of the breast.

  13. Breakthrough Propulsion Physics Workshop Preliminary Results

    Science.gov (United States)

    Millis, Marc G.

    1997-01-01

    In August, 1997, a NASA workshop was held to assess the prospects emerging from physics that might lead to creating the ultimate breakthroughs in space transportation: propulsion that requires no propellant mass, attaining the maximum transit speeds physically possible, and breakthrough methods of energy production to power such devices. Because these propulsion goals are presumably far from fruition, a special emphasis was to identify affordable, near-term, and credible research that could make measurable progress toward these propulsion goals. Experiments and theories were discussed regarding the coupling of gravity and electromagnetism, vacuum fluctuation energy, warp drives and wormholes, and superluminal quantum tunneling. Preliminary results of this workshop are presented, along with the status of the Breakthrough Propulsion Physics program that conducted this workshop.

  14. Stereotactic body radiation therapy via helical tomotherapy to replace brachytherapy for brachytherapy-unsuitable cervical cancer patients – a preliminary result

    Directory of Open Access Journals (Sweden)

    Hsieh CH

    2013-02-01

    Full Text Available Chen-Hsi Hsieh,1–3 Hui-Ju Tien,1 Sheng-Mou Hsiao,4 Ming-Chow Wei,4 Wen-Yih Wu,4 Hsu-Dong Sun,4 Li-Ying Wang,5 Yen-Ping Hsieh,6 Yu-Jen Chen,3,7–9 Pei-Wei Shueng1,101Department of Radiation Oncology, Far Eastern Memorial Hospital, Taipei, Taiwan; 2Department of Medicine, 3Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 4Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, Taipei, Taiwan; 5School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan; 6Department of Senior Citizen Service Management, National Taichung University of Science and Technology, Taichung, Taiwan; 7Department of Radiation Oncology, 8Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan; 9Graduate Institute of Sport Coaching Science, Chinese Culture University, Taipei, Taiwan; 10Department of Radiation Oncology, National Defense Medical Center, Taipei, TaiwanAim: To review the experience and to evaluate the results of stereotactic body radiation therapy (SBRT via helical tomotherapy (HT, for the treatment of brachytherapy-unsuitable cervical cancer.Methods: Between September 1, 2008 to January 31, 2012, nine cervical cancer patients unsuitable for brachytherapy were enrolled. All of the patients received definitive whole pelvic radiotherapy with or without chemotherapy, followed by SBRT via HT.Results: The actuarial locoregional control rate at 3 years was 78%. The mean biological equivalent dose in 2-Gy fractions of the tumor, rectum, bladder, and intestines was 76.0 ± 7.3, 73.8 ± 13.2, 70.5 ± 10.0, and 43.1 ± 7.1, respectively. Only two had residual tumors after treatment, and the others were tumor-free. Two patients experienced grade 3 acute toxicity: one had diarrhea; and another experienced thrombocytopenia. There were no grade 3 or 4 subacute toxicities. Three patients suffered from manageable rectal bleeding in

  15. Imaging Tumor Perfusion and Oxidative Metabolism in Patients With Head-and-Neck Cancer Using 1- [{sup 11}C]-Acetate PET During Radiotherapy: Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Sun Aijun [Section of Nuclear Medicine, Department of Medical Sciences, Uppsala University Hospital, Uppsala (Sweden); Section of Oncology, Department of Radiation Sciences, Umea University Hospital, Umea (Sweden); Johansson, Silvia [Section of Nuclear Medicine, Department of Medical Sciences, Uppsala University Hospital, Uppsala (Sweden); Section of Oncology, Department of Medical Sciences, Uppsala University Hospital, Uppsala (Sweden); Turesson, Ingela [Section of Oncology, Department of Medical Sciences, Uppsala University Hospital, Uppsala (Sweden); Dasu, Alexandru [Department of Radiation Physics, Norrlands University Hospital, Umea (Sweden); Soerensen, Jens, E-mail: jens.sorensen@medsci.uu.se [Section of Nuclear Medicine, Department of Medical Sciences, Uppsala University Hospital, Uppsala (Sweden)

    2012-02-01

    Background: A growing body of in vitro evidence links alterations of the intermediary metabolism in cancer to treatment outcome. This study aimed to characterize tumor oxidative metabolism and perfusion in vivo using dynamic positron emission tomography (PET) with 1- [{sup 11}C]-acetate (ACE) during radiotherapy. Methods and Materials: Nine patients with head-and-neck cancer were studied. Oxidative metabolic rate (k{sub mono}) and perfusion (rF) of the primary tumors were assessed by dynamic ACE-PET at baseline and after 15, 30, and 55 Gy was delivered. Tumor glucose uptake (Tglu) was evaluated with [{sup 18}F]-fluorodeoxyglucose PET at baseline. Patients were grouped into complete (CR, n = 6) and partial responders (PR, n = 3) to radiotherapy. Results: The 3 PR patients died within a median follow-up period of 33 months. Baseline k{sub mono} was almost twice as high in CR as in PR (p = 0.02) and Tglu was lower in CR than in PR (p = 0.04). k{sub mono} increased during radiotherapy in PR (p = 0.004) but remained unchanged in CR. There were no differences in rF between CR and PR at any dosage. k{sub mono} and rF were coupled in CR (p = 0.001), but not in PR. Conclusions: This study shows that radiosensitive tumors might rely predominantly on oxidative metabolism for their bioenergetic needs. The impairment of oxidative metabolism in radioresistant tumors is potentially reversible, suggesting that therapies targeting the intermediary metabolism might improve treatment outcome.

  16. Hypofractionated High-Dose Proton Beam Therapy for Stage I Non-Small-Cell Lung Cancer: Preliminary Results of A Phase I/II Clinical Study

    International Nuclear Information System (INIS)

    Purpose: To present treatment outcomes of hypofractionated high-dose proton beam therapy for Stage I non-small-cell lung cancer (NSCLC). Methods and Materials: Twenty-one patients with Stage I NSCLC (11 with Stage IA and 10 with Stage IB) underwent hypofractionated high-dose proton beam therapy. At the time of irradiation, patient age ranged from 51 to 85 years (median, 74 years). Nine patients were medically inoperable because of comorbidities, and 12 patients refused surgical resection. Histology was squamous cell carcinoma in 6 patients, adenocarcinoma in 14, and large cell carcinoma in 1. Tumor size ranged from 10 to 42 mm (median, 25 mm) in maximum diameter. Three and 18 patients received proton beam irradiation with total doses of 50 Gy and 60 Gy in 10 fractions, respectively, to primary tumor sites. Results: Of 21 patients, 2 died of cancer and 2 died of pneumonia at a median follow-up period of 25 months. The 2-year overall and cause-specific survival rates were 74% and 86%, respectively. All but one of the irradiated tumors were controlled during the follow-up period. Five patients showed recurrences 6-29 months after treatment, including local progression and new lung lesions outside of the irradiated volume in 1 and 4 patients, respectively. The local progression-free and disease-free rates were 95% and 79% at 2 years, respectively. No therapy-related toxicity of Grade ≥3 was observed. Conclusions: Hypofractionated high-dose proton beam therapy seems feasible and effective for Stage I NSCLC. Proton beams may contribute to enhanced efficacy and lower toxicity in the treatment of patients with Stage I NSCLC

  17. Modeling Malaysia's Energy System: Some Preliminary Results

    Directory of Open Access Journals (Sweden)

    Ahmad M. Yusof

    2011-01-01

    Full Text Available Problem statement: The current dynamic and fragile world energy environment necessitates the development of new energy model that solely caters to analyze Malaysia’s energy scenarios. Approach: The model is a network flow model that traces the flow of energy carriers from its sources (import and mining through some conversion and transformation processes for the production of energy products to final destinations (energy demand sectors. The integration to the economic sectors is done exogeneously by specifying the annual sectoral energy demand levels. The model in turn optimizes the energy variables for a specified objective function to meet those demands. Results: By minimizing the inter temporal petroleum product imports for the crude oil system the annual extraction level of Tapis blend is projected at 579600 barrels per day. The aggregate demand for petroleum products is projected to grow at 2.1% year-1 while motor gasoline and diesel constitute 42 and 38% of the petroleum products demands mix respectively over the 5 year planning period. Petroleum products import is expected to grow at 6.0% year-1. Conclusion: The preliminary results indicate that the model performs as expected. Thus other types of energy carriers such as natural gas, coal and biomass will be added to the energy system for the overall development of Malaysia energy model.

  18. Preliminary results from an advanced lighting controlstestbed

    Energy Technology Data Exchange (ETDEWEB)

    Avery, Douglas; Jennings, Judity; Rubinstein, Francis

    1998-03-01

    Preliminary results from a large-scale testbed of advanced lighting control technologies at the Phillip Burton Federal Building at 450 Golden Gate Ave. in San Francisco are presented. The first year objective of this project is to determine the sustainable energy savings and cost-effectiveness of different lighting control technologies compared to a portion of the building where only minimal controls are installed. The paper presents the analyzed results from six months of tests focused on accurately characterizing the energy savings potential of one type of daylight-linked lighting controls compared to the lighting in similar open-planned areas without dimming controls. After analyzing a half year;s data, we determined that the annual energy savings for this type of daylight- linked controls was 41% and 30% for the outer rows of lights on the South and North sides of the building, respectively. The annual energy savings dropped to 22% and 16% for the second row of lights for the South and North, respectively, and was negligible for the third rows of lights.

  19. Preliminary Results on Charmed Meson Spectroscopy

    CERN Document Server

    Sarwar, S; Paolone, V S; Reyes, M; Anjos, J C; Yager, P M; Bediaga, I; Göbel, C; Magnin, J; De Miranda, J M; Pepe, I M; Dos Reis, A C; Simão, F R A; Carrillo, S; Casimiro, E; Méndez, H; Sánchez-Hernández, A; Uribe, C; Vásquez, F; Cinquini, L; Cumalat, J P; Ramírez, J E; O'Reilly, B; Vaandering, E W; Butler, J N; Cheung, H W K; Gaines, I; Garbincius, P H; Garren, L A; Gottschalk, E E; Gourlay, S A; Kasper, P H; Kreymer, A E; Kutschke, R; Bianco, S; Fabbri, Franco Luigi; Sarwar, S; Cawlfield, C; Kim, D Y; Park, K S; Rahimi, A; Gardner, R; Chung, Y S; Kang, J S; Ko, B R; Kwak, J W; Lee, K B; Myung, S S; Alimonti, G; Boschini, M; Brambilla, D; Caccianiga, B; Calandrino, A; D'Angelo, P; Di Corato, M; Dini, P; Giammarchi, M G; Inzani, P; Leveraro, F; Malvezzi, S; Menasce, D; Mezzadri, M; Milazzo, L; Moroni, L; Pedrini, D; Prelz, F; Rovere, M; Sala, A; Sala, S; Arena, V; Boca, G; Bonomi, G; Gianini, G; Liguori, G; Merlo, M; Pantea, D; Ratti, S P; Riccardi, C; Torre, P; Viola, L; Vitulo, P; Hernández, Pilar; López, A M; Méndez, L; Mirles, M A; Montiel, E; Olaya, D; Quinones, J; Rivera, C; Zhang-Mayaguez, Y; Copty, N K; Purohit, M; Cho, K; Handler, T; Engh, D; Johns, W E; Hosack, M; Nehring, M S; Sales, M; Sheldon, P D; Stenson, K; Webster, M S; Sheaff, M; Kwon, Y; Sarwar, Shahzad

    2001-01-01

    We report the preliminary measurement by the FOCUS Collaboration (E831 at Fermilab) of masses and widths of the L=1 charm mesons $D_2^{*0}$ and $D_2^{*+}$. The fit of the invariant mass distribution requires an additional term to account for a broad structure over background.

  20. Tellurium in active volcanic environments: Preliminary results

    Science.gov (United States)

    Milazzo, Silvia; Calabrese, Sergio; D'Alessandro, Walter; Brusca, Lorenzo; Bellomo, Sergio; Parello, Francesco

    2014-05-01

    Tellurium is a toxic metalloid and, according to the Goldschmidt classification, a chalcophile element. In the last years its commercial importance has considerably increased because of its wide use in solar cells, thermoelectric and electronic devices of the last generation. Despite such large use, scientific knowledge about volcanogenic tellurium is very poor. Few previous authors report result of tellurium concentrations in volcanic plume, among with other trace metals. They recognize this element as volatile, concluding that volcanic gases and sulfur deposits are usually enriched with tellurium. Here, we present some results on tellurium concentrations in volcanic emissions (plume, fumaroles, ash leachates) and in environmental matrices (soils and plants) affected by volcanic emissions and/or deposition. Samples were collected at Etna and Vulcano (Italy), Turrialba (Costa Rica), Miyakejima, Aso, Asama (Japan), Mutnovsky (Kamchatka) at the crater rims by using common filtration techniques for aerosols (polytetrafluoroethylene filters). Filters were both eluted with Millipore water and acid microwave digested, and analyzed by inductively coupled plasma mass spectrometry (ICP-MS). Volcanic ashes emitted during explosive events on Etna and Copahue (Argentina) were analyzed for tellurium bulk composition and after leaching experiments to evaluate the soluble fraction of tellurium. Soils and leaves of vegetation were also sampled close to active volcanic vents (Etna, Vulcano, Nisyros, Nyiragongo, Turrialba, Gorely and Masaya) and investigated for tellurium contents. Preliminary results showed very high enrichments of tellurium in volcanic emissions comparing with other volatile elements like mercury, arsenic, thallium and bismuth. This suggests a primary transport in the volatile phase, probably in gaseous form (as also suggested by recent studies) and/or as soluble salts (halides and/or sulfates) adsorbed on the surface of particulate particles and ashes. First

  1. Endovascular repair of aortic aneurysm: Preliminary results

    Directory of Open Access Journals (Sweden)

    Davidović Lazar

    2009-01-01

    Full Text Available Introduction. Endovascular aneurysm repair (EVAR has been introduced into clinical practice at the beginning of the 90's of the last century. Because of economic, political and social problems during the last 25 years, the introduction of this procedure in Serbia was not possible. Objective. The aim of this study was to present preliminary experiences and results of the Clinic for Vascular Surgery of the Serbian Clinical Centre in Belgrade in endovascular treatment of thoracic and abdominal aortic aneurysms. Methods. The procedure was performed in 33 patients (3 female and 30 male, aged from 42 to 83 years. Ten patients had a descending thoracic aorta aneurysm (three atherosclerotic, four traumatic - three chronic and one acute as a part of polytrauma, one dissected, two penetrated atherosclerotic ulcers, while 23 patients had the abdominal aortic aneurysm, one ruptured and two isolated iliac artery aneurysms. The indications for EVAR were isthmic aneurismal localisation, aged over 80 years and associated comorbidity (cardiac, pulmonary and cerebrovasular diseases, previous thoracotomy or multiple laparotomies associated with abdominal infection, idiopatic thrombocitopaenia. All of these patients had three or more risk factors. The diagnosis was established using duplex ultrasonography, angiography and MSCT. In the case of thoracic aneurysm, a Medtronic-Valiant® endovascular stent graft was implanted, while for the abdominal aortic aneurysm Medtronic-Talent® endovascular stent grafts with delivery systems were used. In three patients, following EVAR a surgical repair of the femoral artery aneurysm was performed, and in another three patients femoro-femoral cross over bypass followed implantation of aortouniiliac stent graft. Results. During procedure and follow-up period (mean 1.6 years, there were: one death, one conversion, one endoleak type 1, six patients with endoleak type 2 that disappeared during the follow-up period, one early graft

  2. Incremental value of diffusion weighted and dynamic contrast enhanced MRI in the detection of locally recurrent prostate cancer after radiation treatment: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Akin, Oguz; Vargas, Hebert Alberto; Hricak, Hedvig [Memorial Sloan-Kettering Cancer Center, Department of Radiology, New York, NY (United States); Gultekin, David H. [Memorial Sloan-Kettering Cancer Center, Medical Physics, New York, NY (United States); Zheng, Junting; Moskowitz, Chaya [Memorial Sloan-Kettering Cancer Center, Epidemiology and Biostatistics, New York, NY (United States); Pei, Xin; Sperling, Dahlia; Zelefsky, Michael J. [Memorial Sloan-Kettering Cancer Center, Radiation Oncology, New York, NY (United States); Schwartz, Lawrence H. [Columbia University College of Physicians and Surgeons, Radiology, New York, NY (United States)

    2011-09-15

    To assess the incremental value of diffusion-weighted (DW-MRI) and dynamic contrast-enhanced MRI (DCE-MRI) to T2-weighted MRI (T2WI) in detecting locally recurrent prostate cancer after radiotherapy. Twenty-four patients (median age, 70 years) with a history of radiotherapy-treated prostate cancer underwent multi-parametric MRI (MP-MRI) and transrectal prostate biopsy. Two readers independently scored the likelihood of cancer on a 1-5 scale, using T2WI alone and then adding DW-MRI and DCE-MRI. Areas under receiver operating characteristic curves (AUCs) were estimated at the patient and prostate-side levels. The apparent diffusion coefficient (ADC) from DW-MRI and the K{sup trans}, k{sub ep}, v{sub e}, AUGC90 and AUGC180 from DCE-MRI were recorded. Biopsy was positive in 16/24 (67%) and negative in 8/24 (33%) patients. AUCs for readers 1 and 2 increased from 0.64 and 0.53 to 0.95 and 0.86 with MP-MRI, at the patient level, and from 0.73 and 0.66 to 0.90 and 0.79 with MP-MRI, at the prostate-side level (p values < 0.05). Biopsy-positive and biopsy-negative prostate sides differed significantly in median ADC [1.44 vs. 1.68 (x 10{sup -3} mm{sup 2}/s)], median K{sup trans} [1.07 vs. 0.34 (1/min)], and k{sub ep} [2.06 vs 1.0 (1/min)] (p values < 0.05). MP-MRI was significantly more accurate than T2WI alone in detecting locally recurrent prostate cancer after radiotherapy. (orig.)

  3. Nutritional status at diagnosis in children and adolescents with cancer in the Asociacion de Hemato-Oncologia Pediatrica de Centro America (AHOPCA) countries: preliminary results from Guatemala.

    Science.gov (United States)

    Sala, Alessandra; Rossi, Emanuela; Antillon, Federico

    2008-02-01

    More than 50% of children with cancer in Guatemala have some degree of malnutrition at diagnosis. In particular, the proportions of patients with non-lymphoblastic leukemias and myelodysplasia (MDS) with moderate and severe malnutrition were 73% and 9% respectively; higher than that in the population with acute lymphoblastic leukemia (ALL), P = 0.0493. There was no relationship of nutritional status to gender. Children with ALL and other leukemias + MDS who had severe malnutrition were significantly younger than such malnourished children with solid tumors (P = 0.0003). The relationship of malnutrition to race was mixed, perhaps reflecting the frequent difficulty of accurately categorizing race.

  4. [18F]Choline PET/CT and stereotactic body radiotherapy on treatment decision making of oligometastatic prostate cancer patients: preliminary results

    International Nuclear Information System (INIS)

    A new entity of patients with recurrent prostate cancer limited to a small number of active metastatic lesions is having growing interest: the oligometastatic patients. Patients with oligometastatic disease could eventually be managed by treating all the active lesions with local therapy, i.e. either surgery or ablative stereotactic body radiotherapy. This study aims to assess the impact of [18F]Choline ([18F]FMCH) PET/CT and the use stereotactic body radiotherapy (SBRT) in patients (pts) with oligometastatic prostate cancer (PCa). Twenty-nine pts with oligometastatic PCa (≤3 synchronous active lesions detected with [18F]FMCHPET/CT) were treated with repeated salvage SBRT until disease progression (development of > three active synchronous metastases). Primary endpoint was systemic therapy-free survival measured from the baseline [18F]FMCHPET/CT. A total of 45 lesions were treated with SBRT. After a median follow-up of 11.5 months (range 3–40 months), 20 pts were still in the study and did not receive any systemic therapy. Nine pts started systemic therapy, and the median time of the primary endpoint was 39.7 months (CI 12.20–62.14 months). No grade 3 or 4 toxicity was recorded. Repeated salvage [18F]FMCHPET/CT-guided SBRT is well tolerated and could defer the beginning of systemic therapy in selected patients with oligometastatic PCa

  5. Bioelectrical impedance for detecting and monitoring lymphedema in patients with breast cancer. Preliminary results of the florence nightingale breast study group.

    Science.gov (United States)

    Erdogan Iyigun, Zeynep; Selamoglu, Derya; Alco, Gul; Pilancı, Kezban Nur; Ordu, Cetin; Agacayak, Filiz; Elbüken, Filiz; Bozdogan, Atilla; Ilgun, Serkan; Guler Uysal, Fusun; Ozmen, Vahit

    2015-03-01

    The aim of this study was to evaluate the efficacy of bioimpedance spectroscopy for the follow-up of patients with lymphedema in Turkey and its benefits in the diagnosis of stage 0, 1, and 2 lymphedema in patients who are under treatment for breast cancer. Thirty-seven female patients with breast cancer who underwent surgical procedures in our Breast Health Centre were followed up for lymphedema using bioimpedance, and clinical measurements were taken for a minimum period of 1 year at 3-month intervals. Patients who had been monitored regularly between November, 2011, and September, 2013, were enrolled to the study. In total, 8 patients developed lymphedema with an overall rate of 21.6%. Among the 8 patients who developed lymphedema, 4 had Stage 2, 1 had Stage 1, and 3 had Stage 0 lymphedema. Stage 0 lymphedema could not be detected with clinical measurements. During the patients' 1-year follow-up period using measurements of bioimpedance, a statistically significant relationship was observed between the occurrence of lymphedema and the disease characteristics. including the number of the extracted and remaining lymph nodes and the region of radiotherapy (p=0.042, p=0.024, p=0.040). Bioimpedance analysis seems to be a practical and reliable method for the early diagnosis of lymphedema. It is believed that regular monitoring of patients in the high-risk group using bioimpedance analyses increases the ability to treat lymphedema.

  6. In situ photoimmunotherapy for melanoma: preliminary clinical results

    Science.gov (United States)

    Naylor, Mark F.; Nordquist, Robert E.; Teauge, T. Kent; Perry, Lisa A.; Chen, Wei R.

    2006-02-01

    Although melanoma accounts for only 4% of skin cancer cases, it causes 79% of all skin cancer deaths. Patients with metastatic melanoma have a poor prognosis, and long term survival is only about 5% [1, 2]. Conventional therapies such as surgery and radiation therapy usually do not cure stage III or stage IV melanoma, while traditional chemotherapy is primarily palliative. Over the last decade we have been developing new methods for treating solid tumors like melanoma, first in animal models and now in humans. We present here preliminary results from a new technique that utilizes a combination of laser stimulation and drug therapy to stimulate brisk immunological responses in cases of advanced melanoma with cutaneous metastases. A high-power, near-infrared diode laser (805 nm) is used to kill tumors in situ and a topical toll-like receptor agonist (imiquimod cream, 5%) is used to intensify the resulting immunological response. This is essentially an in situ, tumor vaccine approach to treating solid tumors.

  7. The preliminary result of a prospective study of bladder conserving treatment using transurethral resection, transarterial chemotherapy and local involved field radiotherapy in invasive bladder cancer

    Energy Technology Data Exchange (ETDEWEB)

    Nagano, Hisato; Nagata, Maki; Yamaguchi, Yoshio; Nagashima, Toshiyuki; Tanohata, Kazunori [Yokohama Rosai Hospital (Japan)

    2002-12-01

    Radical cystectomy has been a standard treatment for invasive urinary bladder cancer, however preservation therapy is being considered in many facilities as a clinical examination. After transurethral resection of the bladder (TUR-Bt), three-time transarterial infusion (TAI) of cisplatin (CDDP) 45 mg/m{sup 2}, methotrexate (MTX) 30 mg/m{sup 2} and local five-port external beam radiation therapy (EBRT) of 60 Gy/30 fx/ 6 wks were delivered concurrently. Because such reports of organ sparing treatment using TAI are few, a mono-arm prospective study was designed to evaluate the rate of complete response (CR) (Response Evaluation Criteria In Solid Tumor (RECIST) standard) and the incidence of acute toxicity (National Cancer Institute (NCI) standard) compared with previous reports in which intravenous chemotherapy was used in a tri-modality treatment protocol. Twenty-three patients with T{sub 2-4}N{sub 0}M{sub 0} or High risk T{sub 1}N{sub 0}M{sub 0} were registered (T{sub 1}; 7, T{sub 2}; 7, T{sub 3}; 8, T{sub 4}; 1). They were all in good performance status (PS) (0-1). CR rate after intravesical therapy with bacilli Calmette-Guerin (BCG) was eighty-seven percent (confidence interval (CI) 66-97%). There was a significant difference (p=0.03) between this value and that (CR rate=62%, n=299) calculated from two reports in which transvenous chemotherapy was used as one of the treatment modalities. Grade three white blood cell decrease was seen in twenty-six percent of patients. This was significantly higher than the value estimated from reports using cisplatin only as the single chemotherapy agent. An acute reaction of the urinary bladder and rectum was negligible. After fifteen-month follow-up, four patients relapsed and two showed metastatic lesions. According to the protocol, three of the former four had already received cystectomy, but one had undergone an intra-vesicle BCG injection because it showed non-invasive papillary histology, and reached CR again. M

  8. Expresión de bcl-2, ki-67 y caspasa-3 en lesiones cancerosas de la mucosa oral: Resultados preliminares Blc-2, ki-67 and caspasa-3 expression in oral cancer lesions: Preliminary results

    Directory of Open Access Journals (Sweden)

    V García García

    2006-10-01

    Full Text Available El cáncer oral representa del 2 al 4% de todos los cánceres diagnosticados, siendo el carcinoma epidermoide el tumor más común encontrado a nivel histológico. En varios estudios se ha constatado que el uso de la clasificación TNM del cáncer oral no resulta de utilidad a la hora de establecer el pronóstico tumoral. Nos encontramos en la era de los marcadores tumorales que actualmente pueden ser detectados y medidos con las más modernas técnicas de inmunohistoquímica. Material y método: aplicación de la técnica inmunohistoquímica peroxidasa- antiperoxidasa para la detección de las moléculas bcl-2, caspasa-3 y Ki-67 en lesiones cancerosas. Resultados preliminares y discusión: la detección molecular del marcador antiapoptótico bcl-2, el marcador proapoptótico caspasa 3 y el marcador de proliferación celular Ki-67 nos informará sobre la situación más o menos grave del paciente respecto de su proceso canceroso.Oral cancer represents 2%-4% of all types of cancer that are diagnosed and epidermal carcinoma is the most common tumour found in oral cavity. Some experimental studies have shown that TNM classification is not useful when you want to know tumour prognosis. Now we are in the modern inmunohistochemical period with new techniques for cancer diagnose. Material and method: use the peroxidase-antiperoxidase inmunohistochemical technique to detect bcl-2, caspasa-3 and Ki-67 molecules in cancerous lesions. Preliminary results and discussion: molecular detection of the antiapoptotic bcl-2 molecule, the proapoptotic caspasa-3 molecule and the cellular proliferation indicator Ki-67 will show us about the gravity of the patient situation.

  9. The use of skin surface electropotentials for breast cancer detection--preliminary clinical trial results obtained using the biofield diagnostic system.

    Science.gov (United States)

    Sree, Subbhuraam Vinitha; Ng, E Y K; Kaw, G; U, Rajendra Acharya; Chong, B K

    2011-02-01

    The purpose of this study is to evaluate the efficiency of the Biofield Diagnostic System (BDS) as an adjunct to established diagnostic techniques such as mammography and ultrasound in differentiating benign and malignant breast lesions. The clinical trial was conducted at the Tan Tock Seng hospital, Singapore. 103 women scheduled for mammography and/or ultrasound tests participated in the study. The BDS test recorded a sensitivity of 100%, specificity of 97.6%, and an accuracy of 98.1%. The area under the ROC curve was 0.988 which was slightly lower than that of ultrasound (0.994) and slightly higher than that of mammography (0.951). The BDS test has demonstrated high sensitivity and specificity values in the studied population. The accuracy is also comparable to that of diagnostic techniques like mammography and ultrasound. Thus, it is evident that BDS can be a fast and reliable adjunct tool for getting a secondary opinion on lesions with indeterminate mammographic and sonographic results.

  10. The use of skin surface electropotentials for breast cancer detection--preliminary clinical trial results obtained using the biofield diagnostic system.

    Science.gov (United States)

    Sree, Subbhuraam Vinitha; Ng, E Y K; Kaw, G; U, Rajendra Acharya; Chong, B K

    2011-02-01

    The purpose of this study is to evaluate the efficiency of the Biofield Diagnostic System (BDS) as an adjunct to established diagnostic techniques such as mammography and ultrasound in differentiating benign and malignant breast lesions. The clinical trial was conducted at the Tan Tock Seng hospital, Singapore. 103 women scheduled for mammography and/or ultrasound tests participated in the study. The BDS test recorded a sensitivity of 100%, specificity of 97.6%, and an accuracy of 98.1%. The area under the ROC curve was 0.988 which was slightly lower than that of ultrasound (0.994) and slightly higher than that of mammography (0.951). The BDS test has demonstrated high sensitivity and specificity values in the studied population. The accuracy is also comparable to that of diagnostic techniques like mammography and ultrasound. Thus, it is evident that BDS can be a fast and reliable adjunct tool for getting a secondary opinion on lesions with indeterminate mammographic and sonographic results. PMID:20703583

  11. Results of a planned interim toxicity analysis with trimodality therapy, including carboplatin AUC = 4, paclitaxel, 5-fluorouracil, amifostine, and radiation for locally advanced esophageal cancer: preliminary analyses and treatment recommendations from the North Central Cancer Treatment Group

    OpenAIRE

    Jatoi, Aminah; Martenson, James; Mahoney, Michelle R; Lair, Bradley S; Brindle, Jeffrey S; Nichols, Frank; Caron, Normand; Rowland, Kendrith; Tschetter, Loren; Alberts, Steven

    2004-01-01

    Purpose An aggressive trimodality approach from the Minnie Pearl Cancer Research Network [carboplatin AUC = 6, days 1 and 22; 5-fluorouracil 225 mg/m2 continuous infusion, days 1–42, paclitaxel 200 mg/m2, days 1 and 22; 45 Gy] has resulted in remarkable pathologic response rates but notable toxicity. This trial was designed to mitigate this toxicity by starting with a lower carboplatin dose, AUC = 4, and by adding subcutaneous amifostine. Methods This phase II trial included patients with loc...

  12. 11C choline PET guided salvage radiotherapy with volumetric modulation arc therapy and hypofractionation for recurrent prostate cancer after HIFU failure: preliminary results of tolerability and acute toxicity.

    Science.gov (United States)

    Alongi, Filippo; Liardo, Rocco L E; Iftode, Cristina; Lopci, Egesta; Villa, Elisa; Comito, Tiziana; Tozzi, Angelo; Navarria, Pierina; Ascolese, Anna M; Mancosu, Pietro; Tomatis, Stefano; Bellorofonte, Carlo; Arturo, Chiti; Scorsetti, Marta

    2014-10-01

    The purpose of this work was to evaluate tolerance, feasibility and acute toxicity in patients undergoing salvage radiotherapy after high-intensity focused ultrasound (HIFU) failure. From 2005 to 2011 a total of 15 patients were treated with HIFU as primary radical treatment. Between July 2011 and February 2013, all 15 patients presented biochemical relapse after HIFU and 11C choline PET documenting intrapostatic-only failure. Salvage EBRT was performed with moderate hypofractionation schedule in 28 fractions with volumetric modulation arc therapy (VMAT). Genito-urinary (GU) and rectal and bowel toxicity were scored by common terminology criteria for adverse events version 4 (CTCAE V.4) scale. Biochemical response was assessed by ASTRO Phoenix criteria. Median age of patients was 67 years (range: 53-85). The median Gleason score was 7 (range: 6-9). The median prostate specific antigen (PSA) at the time of biochemical relapse after HIFU was 5.2 ng/mL (range: 2-64.2). Seven of the 15 patients received androgen deprivation therapy (ADT) started after HIFU failure, interrupted before 11C choline PET and radiotherapy. Median prescribed dose was 71.4 Gy (range: 71.4-74.2 Gy) in 28 fractions. No radiation related major upper gastrointestinal (GI), rectal and GU toxicity were experienced. GU, acute grade 1 and grade 2 toxicities were recorded in 7/15 and 4/15 respectively; bowel acute grade 1 and grade 2 toxicities in 4/15 and 1/15; rectal acute grade 1 and grade 2 toxicities in 3/15 and 2/15 respectively. No grade 3 or greater acute or late toxicities occurred. Biochemical control was assessed in 12/15 (80%) patients. With a median follow up of 12 months, three out of 15 patients, with biochemical relapse, showed lymph-nodal recurrence. Our early clinical results and biochemical data confirm the feasibility and show a good tolerance of the 11C choline PET guided salvage radiation therapy after HIFU failure. The findings of low acute toxicity is encouraging, but longer

  13. Low-dose-rate brachytherapy as the sole radiation modality in the management of patients with early-stage breast cancer treated with breast-conserving therapy: preliminary results of a pilot trial

    International Nuclear Information System (INIS)

    Purpose: We present the preliminary findings of our in-house protocol treating the tumor bed alone after lumpectomy with low-dose-rate (LDR) interstitial brachytherapy in selected patients with early-stage breast cancer treated with breast-conserving therapy (BCT). Methods and Materials: Since March 1, 1993, 60 women with early-stage breast cancer were entered into a protocol of tumor bed irradiation only using an interstitial LDR implant with iodine-125. Patients were eligible if the tumor was ≤3 cm, margins were ≥2 mm, there was no extensive intraductal component, the axilla was surgically staged, and a postoperative mammogram was performed. Implants were placed using a standardized template either at the time of reexcision or shortly after lumpectomy. A total of 50 Gy was delivered at 0.52 Gy/h over a period of 96 h to the lumpectomy bed plus a 2-cm margin. Perioperative complications, cosmetic outcome, and local control were assessed. Results: The median follow-up for all patients is 20 months. Three patients experienced minimal perioperative pain that required temporary nonnarcotic analgesics. There have been four postoperative infections which resolved with oral antibiotics. No significant skin reactions related to the implant were noted and no patient experienced impaired would healing. Early cosmetic results reveal minimal changes consisting of transient hyperpigmentation of the skin at the puncture sites and temporary induration in the tumor bed. Good to excellent cosmetic results were noted in all 19 patients followed up a minimum of 24 months posttherapy. To date, 51 women have obtained 6-12-month follow-up mammograms and no recurrences have been noted. All patients currently have no physical signs of recurrence, and no patient has failed regionally or distantly. Conclusion: Treatment of the tumor bed alone with LDR interstitial brachytherapy appears to be well tolerated, and early results are promising. Long-term follow-up of these patients is

  14. [Preliminary results of treatment with aflibercept].

    Science.gov (United States)

    Blăjan, Codruta; Nicula, D; Rusu, Ioana

    2014-01-01

    The paper presents the first results concerning the Aflibercept (Eylea) treatment, the last antiVEGF approved for treatment of the age related macular degeneration (AMD), neovascular form and for macular edema due to the central retinal vein occlusion. The treatment was applied to patients presenting AMD, ME and other diseases: myopic and idiopatic choroidal neovascularisation, central serous choroidopathy (CSC) or diabetic macular edema (DME). The results were good: improvement of the visual acuity, resolution of the intraretinal fluids and macular edema. Although we did not notice major side-effects, resistance or tachyphylaxis, we noticed some recurrences.

  15. Preliminary results of impeller design modifications

    International Nuclear Information System (INIS)

    Power consumption in the oil mixing process is very much affected by the impeller design. Minor modification on the impeller design might result in better mixing and less energy consumption. This paper reports an early stage of applying the observation technique to modify three standard impellers, namely the Pitched blade turbine impeller, the CHEMSHEAR impeller and the Vertical Flat-Blade Turbine Impeller. The advantages and disadvantages of these three impellers were analyzed; accordingly minor modification on the impeller design is adopted. The CFD tool is used to evaluate one of the modified impellers; results indicated that the modified impeller achieves better fluid dispersion.

  16. Preliminary results of steel containment vessel model test

    Energy Technology Data Exchange (ETDEWEB)

    Luk, V.K.; Hessheimer, M.F. [Sandia National Labs., Albuquerque, NM (United States); Matsumoto, T.; Komine, K.; Arai, S. [Nuclear Power Engineering Corp., Tokyo (Japan); Costello, J.F. [Nuclear Regulatory Commission, Washington, DC (United States)

    1998-04-01

    A high pressure test of a mixed-scaled model (1:10 in geometry and 1:4 in shell thickness) of a steel containment vessel (SCV), representing an improved boiling water reactor (BWR) Mark II containment, was conducted on December 11--12, 1996 at Sandia National Laboratories. This paper describes the preliminary results of the high pressure test. In addition, the preliminary post-test measurement data and the preliminary comparison of test data with pretest analysis predictions are also presented.

  17. Modality-independent elastography: preliminary results

    Science.gov (United States)

    Washington, Chad W.; Miga, Michael I.

    2004-05-01

    The correlation between the stiffness and health of tissue is an accepted form of organ disease assessment. As a result, there has been a significant amount of interest in developing methods to image elasticity parameters (i.e. elastography). This work presents a technique that frames the elastography imaging problem within a non-rigid iterative image registration approach. Through the use of finite element modeling and mutual information, material properties are varied in order to optimize the registration between a post-compressed image and a model-generated compressed image. The results shown here demonstrate the strong connection between image similarity and appropriate tissue parameters and the algorithm's ability to detect contrast in tissue stiffness. By casting elasticity image reconstruction within the context of image similarity, the method is generalized to all forms of medical imaging.

  18. Preliminary Experimental Results for Tritium Accountancy Measurement

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Do Yeon; Chung, Hong Suk; Chung, Dong You; Koo, Dae Seo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2010-10-15

    The SDS (storage and delivery system) is one of the major components of ITER fuel cycle. The main function of the SDS is to store the hydrogen isotopes and deliver them to the fuel injection system. The tritium inventory of the bed is determined from the decay heat of the tritium without removing the inventory from bed. The decay heat is measured by the in-bed calorimetry. He through the ZrCo bed and measuring the resultant temperature increase of the He flow. Korea has been various test results for the experimental ZrCo beds. Based on this result, we propose concept of tray type ZrCo bed. ZrCo was reacted with the hydrogen ingressed through SUS filter(120mesh) placed in the tray. The heating coils and the helium loop for the inbed calorimetry are installed bottom of the tray. In this paper, we performed thermo analysis on the in-bed calorimetry performance of the bed. Using the software, LABVIEW, the time-dependent temperature distribution of the bed, the temperature difference ({Delta} T) between the inlet and outlet of the flow through the helium loop

  19. Percutaneous renal puncture: requirements and preliminary results

    CERN Document Server

    Leroy, A; Payan, Y; Richard, F; Chartier-Kastler, E; Troccaz, J; Leroy, Antoine; Mozer, Pierre; Payan, Yohan; Chartier-Kastler, Emmanuel; Troccaz, Jocelyne

    2002-01-01

    This paper introduces the principles of computer assisted percutaneous renal puncture, that would provide the surgeon with an accurate pre-operative 3D planning on CT images and, after a rigid registration with space-localized echographic data, would help him to perform the puncture through an intuitive 2D/3D interface. The whole development stage relied on both CT and US images of a healthy subject. We carried out millimetric registrations on real data, then guidance experiments on a kidney phantom showed encouraging results.

  20. Medical Radioisotope Data Survey: 2002 Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Siciliano, Edward R.

    2004-06-23

    A limited, but accurate amount of detailed information about the radioactive isotopes used in the U.S. for medical procedures was collected from a local hospital and from a recent report on the U.S. Radiopharmaceutical Markets. These data included the total number of procedures, the specific types of procedures, the specific radioisotopes used in these procedures, and the dosage administered per procedure. The information from these sources was compiled, assessed, pruned, and then merged into a single, comprehensive and consistent set of results presented in this report. (PIET-43471-TM-197)

  1. Modelling Extortion Racket Systems: Preliminary Results

    Science.gov (United States)

    Nardin, Luis G.; Andrighetto, Giulia; Székely, Áron; Conte, Rosaria

    Mafias are highly powerful and deeply entrenched organised criminal groups that cause both economic and social damage. Overcoming, or at least limiting, their harmful effects is a societally beneficial objective, which renders its dynamics understanding an objective of both scientific and political interests. We propose an agent-based simulation model aimed at understanding how independent and combined effects of legal and social norm-based processes help to counter mafias. Our results show that legal processes are effective in directly countering mafias by reducing their activities and changing the behaviour of the rest of population, yet they are not able to change people's mind-set that renders the change fragile. When combined with social norm-based processes, however, people's mind-set shifts towards a culture of legality rendering the observed behaviour resilient to change.

  2. Preliminary results of stevia plant (Stevia rebaudiana

    Directory of Open Access Journals (Sweden)

    NOC FASLLIA

    2014-06-01

    Full Text Available The study was conducted at the experimental plots of the Agricultural Technology Transfer Center(ATTC Fushe - Kruja, from 2013 to 2014. The objectives of this study were, recognition with bio morphology of the growth and development of Stevios plant under conditions of our country. The study design consists of 30 plant pots planted with the STEVIAS. Indicators studied, were: time of planting, the beginning of growth, plant growth height in cm, number of brothers, number of branches in the main branch, the average number of leaves, total number of leaves. Planting was carried out on 20 February 2013, followed by the onset of growth on 3/25/2013 to 3/04/2014, ripening and harvest in September 5-10 October. At the end of the production these results were taken according to the study indicators. The height of the plant was carried 71.53 ± 11.08cm, depending on feeding conditions and illumination which according to requirements of this plant is one of the most dominant factors. The average number of brothers per branch is to 10.6 ± 2.4, which shows a high potential for stevia plant production. The average number of leaves per branch is 48.13 ± 9.26, and with a total leaves of 517. 03 ± 176.25, which are quantitative harvestable indicators of plant. Weight of plant was conducted at 49.46 ± 4.987gr.

  3. Renal imaging at 7 Tesla: preliminary results

    International Nuclear Information System (INIS)

    To investigate the feasibility of 7T MR imaging of the kidneys utilising a custom-built 8-channel transmit/receive radiofrequency body coil. In vivo unenhanced MR was performed in 8 healthy volunteers on a 7T whole-body MR system. After B0 shimming the following sequences were obtained: 1) 2D and 3D spoiled gradient-echo sequences (FLASH, VIBE), 2) T1-weighted 2D in and opposed phase 3) True-FISP imaging and 4) a T2-weighted turbo spin echo (TSE) sequence. Visual evaluation of the overall image quality was performed by two radiologists. Renal MRI at 7T was feasible in all eight subjects. Best image quality was found using T1-weighted gradient echo MRI, providing high anatomical details and excellent conspicuity of the non-enhanced vasculature. With successful shimming, B1 signal voids could be effectively reduced and/or shifted out of the region of interest in most sequence types. However, T2-weighted TSE imaging remained challenging and strongly impaired because of signal heterogeneities in three volunteers. The results demonstrate the feasibility and diagnostic potential of dedicated 7T renal imaging. Further optimisation of imaging sequences and dedicated RF coil concepts are expected to improve the acquisition quality and ultimately provide high clinical diagnostic value. (orig.)

  4. Metal rich stars in omega Cen: preliminary FLAMES GTO results

    CERN Document Server

    Pancino, E

    2004-01-01

    I present preliminary results for a sample of ~700 red giants in omega Cen, observed during the Ital-FLAMES Consortium GTO time in May 2003, for the Bologna Project on omega Cen. Preliminary Fe and Ca abundances confirm previous results: while the metal-poor and intermediate populations show a normal halo alpha-enhancement of [alpha/Fe]=$+0.3, the most metal-rich stars show a significantly lower [alpha/Fe]=+0.1. If the metal-rich stars have evolved within the cluster in a process of self-enrichment, the only way to lower their alpha-enhancement would be SNe type Ia intervention.

  5. Connecticut Transit (CTTRANSIT) Fuel Cell Transit Bus: Preliminary Evaluation Results

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, K.; Eudy, L.

    2008-10-01

    This report provides preliminary results from a National Renewable Energy Laboratory evaluation of a protoptye fuel cell transit bus operating at Connecticut Transit in Hartford. Included are descriptions of the planned fuel cell bus demonstration and equipment; early results and agency experience are also provided.

  6. The 2dF Galaxy Redshift Survey: Preliminary Results

    OpenAIRE

    Maddox, S.

    1997-01-01

    Spectroscopic observations for a new survey of 250 000 galaxy redshifts are underway, using the 2dF instrument at the AAT. The input galaxy catalogue and commissioning data are described. The first result from the preliminary data is a new estimate of the galaxy luminosity function at =0.1.

  7. The friction of polymers around Tg,Tm : Preliminary results

    DEFF Research Database (Denmark)

    Sivebæk, Ion Marius; Samoilov, V N; Persson, B N J

    We present Molecular Dynamics calculations involving polymers of different lengths. Polymers with lengths from 20 to 1400 carbon atoms are considered. The systems are able to simulate friction between polymer surfaces and polymer against metal. The results we present are very preliminary and they...

  8. Breast ultrasound tomography with two parallel transducer arrays: preliminary clinical results

    Science.gov (United States)

    Huang, Lianjie; Shin, Junseob; Chen, Ting; Lin, Youzuo; Intrator, Miranda; Hanson, Kenneth; Epstein, Katherine; Sandoval, Daniel; Williamson, Michael

    2015-03-01

    Ultrasound tomography has great potential to provide quantitative estimations of physical properties of breast tumors for accurate characterization of breast cancer. We design and manufacture a new synthetic-aperture breast ultrasound tomography system with two parallel transducer arrays. The distance of these two transducer arrays is adjustable for scanning breasts with different sizes. The ultrasound transducer arrays are translated vertically to scan the entire breast slice by slice and acquires ultrasound transmission and reflection data for whole-breast ultrasound imaging and tomographic reconstructions. We use the system to acquire patient data at the University of New Mexico Hospital for clinical studies. We present some preliminary imaging results of in vivo patient ultrasound data. Our preliminary clinical imaging results show promising of our breast ultrasound tomography system with two parallel transducer arrays for breast cancer imaging and characterization.

  9. Hellenic Amateur Astronomy Association's activities: Preliminary results on Perseids 2010

    Science.gov (United States)

    Maravelias, G.

    2011-01-01

    Preliminary results on the Perseids 2010 are presented. Visual and video observations were obtained by the author and a first reduction of the visual data shows that a maximum of ZHR ~120 was reached during the night 12-13 of August 2010. Moreover, a video setup was tested (DMK camera and UFO Capture v2) and the results show that, under some limitations, valuable data can be obtained.

  10. Preliminary Results of the MOSES II 2015 Flight

    Science.gov (United States)

    Smart, Roy; Courrier, Hans; Kankelborg, Charles

    2016-05-01

    The Multi-Order Extreme Ultraviolet Spectrograph (MOSES) is a slitless spectrograph which aims to produce simultaneous spatial-spectral imaging of the solar transition region. This is accomplished through a multilayer concave diffraction grating which produces three images for the spectral orders m = 0, ± 1. The multilayer coating provides a narrow passband, dominated by Ne VII (46.5 nm), which allows the three images to be compared in order to determine line broadenings and identify explosive events in the Solar Transition Region. Here, we examine the preliminary results of MOSES II, the instrument’s second flight which was launched on a sounding rocket from White Sands Missile Range, NM in August 2015. We present the first images of the Sun in Ne VII since Skylab and the preliminary results of observed doppler shifts within an active region.

  11. Preliminary results of the echo-seeding experiment at SLAC

    Energy Technology Data Exchange (ETDEWEB)

    Xiang, D.; Colby, E.; Ding, Y.; Dunning, M.; Frederico, J.; Gilevich, S.; Hast, C.; Jobe, K.; McCormick, D.; Nelson, J.; Raubenheimer, T.O.; Soong, K.; Stupakov, G.; Szalata, Z.; Walz, D.; Weathersby, S.; Woodley, M.; Corlett, J.; Qiang, J.; Penn, G.; Prestemon, S.; Schlueter, R.; Venturini, M.; Wan, W.; Pernet, P-L.

    2010-05-23

    ECHO-7 is a proof-of-principle echo-enabled harmonic generation FEL experiment in the Next Linear Collider Test Accelerator (NLCTA) at SLAC. The experiment aims to generate coherent radiation at 318 nm and 227 nm, which are the 5th and 7th harmonic of the infrared seed laser. In this paper we present the preliminary results from the commissioning run of the completed experimental setup which started in April 2010.

  12. Intercomparison Of Spectroradiometers For Solar Spectral Irradiance Measurements. Preliminary Results.

    OpenAIRE

    Galleano, Roberto; ZAAIMAN Willem; MORABITO Paolo; Minuto, Alessandro; Spena, Angelo; Bartocci, Simona; Fucci, Raffaele; Leanza, Gianni; PAVANELLO Diego; VIRTUANI Alessandro; FASANARO Daniela; CATENA Mario; NORTON Matthew

    2011-01-01

    This paper describes the preliminary results of an intercomparison of spectroradiometers for direct (DNI) and global normal incidence (GNI) irradiance in the visible (VIS) and near infrared (NIR) region. Seven institutions and six spectroradiometers, representing different technologies and manufacturers were involved. All instruments were able to measure GNI; a restricted sub-group of four instruments had the possibility to also measure DNI when equipped with proper collimators. P...

  13. 9.4T Human MRI: Preliminary Results

    OpenAIRE

    VAUGHAN, THOMAS; DelaBarre, Lance; Snyder, Carl; Tian, Jinfeng; Akgun, Can; Shrivastava, Devashish; Liu, Wanzahn; Olson, Chris; Adriany, Gregor; Strupp, John; Andersen, Peter; Gopinath, Anand; Van de Moortele, Pierre-Francois; Garwood, Michael; Ugurbil, Kamil

    2006-01-01

    This work reports the preliminary results of the first human images at the new high-field benchmark of 9.4T. A 65-cm-diameter bore magnet was used together with an asymmetric 40-cm-diameter head gradient and shim set. A multichannel transmission line (transverse electromagnetic (TEM)) head coil was driven by a programmable parallel transceiver to control the relative phase and magnitude of each channel independently. These new RF field control methods facilitated compensation for RF artifacts...

  14. I Might Have Some Bad News: Disclosing Preliminary Pathology Results.

    Science.gov (United States)

    Roh, Michael H; Shuman, Andrew G

    2016-01-01

    Cytopathology is a subspecialty of pathology in which pathologists frequently interact directly with patients. Often this interaction is in the context of fine needle aspiration (FNA) procedures performed at the bedside by the cytopathologist or by another clinician with the cytopathologist present. Patient requests for preliminary results in such settings raise fundamental questions about professional scope of practice and communication of uncertainty that apply not merely to pathologists but to all clinicians. In certain settings, cytopathologists may share preliminary diagnostic impressions directly with patients. Essential to these conversations is the need to articulate potential uncertainty about both the diagnosis and next steps. In addition, the involvement and notification of the referring physician is obligatory, both for care coordination and to ensure that patients receive a consistent message. PMID:27550561

  15. Cancer risk following radiotherapy of cervical cancer: A preliminary report

    International Nuclear Information System (INIS)

    Women treated for cervical cancer were selected for study because (a) doses to body organs following radiotherapy can be accurately determined and vary sufficiently to permit dose-response evaluations, (b) organs remote from the cervix receive low-dose exposures in the range of current scientific interest, (c) treatment is relatively successful and many patients survive long enough to be at risk of late complications of radiotherapy, and (d) several nonexposed groups of women with cervical cancer are also available for comparison. In addition, population-based cancer registries provide an opportunity to inexpensively study large numbers of individuals over many decades. The careful procedures normally used by cancer registries to record second primary cancers facilitate the study of cancer incidence for which a wider view of radiation risk is expected than can be seen in investigations of mortality. Other special features of studies of cervical cancer patients include the ability to assess the effects of very large partial-body exposures, differences in organ sensitivities to radiation, interactions of radiation with biological factors such as age, and the duration of carcinogenic response

  16. Helium at white dwarf photospheric conditions: preliminary laboratory results

    CERN Document Server

    Schaeuble, Marc; Gomez, Thomas A; Winget, Don E; Montgomery, Michael H; Bailey, James E

    2016-01-01

    We present preliminary results of an experimental study exploring helium at photospheric conditions of white dwarf stars. These data were collected at Sandia National Laboratories' Z-machine, the largest x-ray source on earth. Our helium results could have many applications ranging from validating current DB white dwarf model atmospheres to providing accurate He pressure shifts at varying temperatures and densities. In a much broader context, these helium data can be used to guide theoretical developments in new continuum-lowering models for two-electron atoms. We also discuss future applications of our updated experimental design, which enables us to sample a greater range of densities, temperatures, and gas compositions.

  17. Preliminary Results on Uncertainty Quantification for Pattern Analytics

    Energy Technology Data Exchange (ETDEWEB)

    Stracuzzi, David John [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Brost, Randolph [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Chen, Maximillian Gene [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Malinas, Rebecca [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Peterson, Matthew Gregor [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Phillips, Cynthia A. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Robinson, David G. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Woodbridge, Diane [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    This report summarizes preliminary research into uncertainty quantification for pattern ana- lytics within the context of the Pattern Analytics to Support High-Performance Exploitation and Reasoning (PANTHER) project. The primary focus of PANTHER was to make large quantities of remote sensing data searchable by analysts. The work described in this re- port adds nuance to both the initial data preparation steps and the search process. Search queries are transformed from does the specified pattern exist in the data? to how certain is the system that the returned results match the query? We show example results for both data processing and search, and discuss a number of possible improvements for each.

  18. Instalação e resultados preliminares de programa de rastreamento populacional de câncer colorretal em município brasileiro Screening of colorectal cancer in a Brazilian town - preliminary results

    Directory of Open Access Journals (Sweden)

    Rodrigo Oliva Perez

    2008-03-01

    , 3.640 exames foram analisados, o que corresponde a 43,7% da população alvo e 79,7% dos exames distribuídos. Foram obtidos 390 exames com resultado positivo (10,7% e 3.250 negativos (89,3%. Dos 245 pacientes positivos convocados a realizar colonoscopia, 33 (13,5% se recusaram. Das 212 colonoscopias realizadas foram diagnosticados: 53 pacientes com doença diverticular, 59 com 1 ou mais pólipos, 9 com adenocarcinomas e 91 colonoscopias normais. Os pacientes com adenocarcinoma, 3 foram tratados endoscopicamente por portarem lesão pequena e precoce, os outros 6 pacientes foram encaminhados para tratamento cirúrgico e quimioterápico. CONCLUSÕES: Os resultados preliminares são insuficientes para estimar qual foi o real efeito da campanha, contudo, pode-se antever redução da incidência de CCR a longo prazo, além de antecipação do diagnóstico e, portanto, do estádio da doença melhorando o prognóstico.BACKGROUND: The colorectal cancer accounts for about 500,000 deaths/year worldwide and ranks third in death by neoplasia. Patient mortality is directly related to its stage when diagnosed. Screening allows early diagnosis, reason why it turns out to be an effective tool to reduce mortality. AIM: To assess the impacts of the colorectal cancer prevention campaign in a Brazilian municipality, to estimate the disease occurrence and to forecast reduction of its incidence in the long term. METHODS: The Giant Colon, a replica of the human colon, created by ABRAPRECI, was exposed in the local Sports Gymnasium, in order to educate the population on the parts of the organ and the main diseases affecting it. Screening was then performed with the occult blood test kit, (Hemosure®, immunological type, in the population over 40 years of age, asymptomatic and without previous CRC screening. People with negative results were registered for annual control and those with positive result were referred to colonoscopy to determine the presence of neoplasic or pre

  19. Preliminary results on Niobium sputtered films inside TESLA type cavities

    International Nuclear Information System (INIS)

    In the framework of the ARES project and as a possible application for TESLA we realized a test set-up to study the deposition of Nb films inside a single-cell TESLA type cavity. The plasma confinement was obtained with two external coils centered on the cavity axis in a magnetic bottle configuration. The system is operational and optimization of the discharge parameters is in progress: samples are produced to test the film quality. This paper covers a brief description of the test set-up and preliminary results on samples (thickness, RRR, and XRD measurements). (author)

  20. Preliminary results of dark-speckle stellar coronography

    CERN Document Server

    Boccaletti, A; Ragazzon, R

    1998-01-01

    The dark-speckle method (Labeyrie 1995) combines features of speckle interferometry and adaptive optics to provide images of faint circumstellar material. We present preliminary results of observations, and simulations concluding to the feasibility of exo-planet imaging from the ground. Laboratory simulations with an avalanche photodiode indicate the detectability of a stellar companion of relative intensity 10^{-6} at 5 Airy radii from the star. New, more general, expressions for the signal-to-noise ratio and integration time are given. Comparisons with direct long-exposure imaging indicate that the method improves the detectability of circumstellar nebulosity, faint companions and planets.

  1. Ruptured Achilles tendon--preliminary results of a new treatment.

    OpenAIRE

    Cetti, R.

    1988-01-01

    The preliminary results of a new treatment of ruptured Achilles tendons are presented. The new treatment consists of a new tendon suture and a new post-operative cast in which it is possible to make non-weight bearing movements of the ankle immediately after the operation. This makes it possible to walk the day after the operation, causes very little discomfort during the time in a cast, gives a quick return to normal mobility with normal plantar flexion strength and makes it possible to resu...

  2. Recent Development and Preliminary Results of Chinese Meridian Project

    Institute of Scientific and Technical Information of China (English)

    WANG Chi; REN Liwen

    2013-01-01

    The Meridian Project is a ground-based network program to monitor solar-terrestrial space environment,which consists of a chain of 15 ground-based observatories located roughly along 120°E longitude and 30°N latitude.The Meridian project started in 2008,and its construction was completed by 2011.The integration and test phase of the Meridian Project conducted in 2011 demonstrated its observation capabilities as expected.The project will be in full operation in 2012.This report gives an overview of the recent development and preliminary results of the Meridian Project since 2010.

  3. Escherichia coli O26 IN RAW BUFFALO MILK: PRELIMINARY RESULTS

    Directory of Open Access Journals (Sweden)

    A. Rella

    2013-02-01

    Full Text Available Escherichia coli O26 is considered to be one of the most important food-borne pathogen. In this study, 120 buffalo milk samples collected in Lazio and in Apulia regions were tested for the presence of E. coli O26. One buffalo milk sample (0,8% tested positive for E. coli O26; the isolate was positive at the verocytotoxicity test and it showed resistance properties to different antimicrobial classes. These preliminary results highlight the need to monitor the foods of animal origin used for production and eaten by a wide range of persons, respect VTEC organism.

  4. V and V Efforts of Auroral Precipitation Models: Preliminary Results

    Science.gov (United States)

    Zheng, Yihua; Kuznetsova, Masha; Rastaetter, Lutz; Hesse, Michael

    2011-01-01

    Auroral precipitation models have been valuable both in terms of space weather applications and space science research. Yet very limited testing has been performed regarding model performance. A variety of auroral models are available, including empirical models that are parameterized by geomagnetic indices or upstream solar wind conditions, now casting models that are based on satellite observations, or those derived from physics-based, coupled global models. In this presentation, we will show our preliminary results regarding V&V efforts of some of the models.

  5. Efficacy of perioperative administration of long-acting bronchodilator on postoperative pulmonary function and quality of life in lung cancer patients with chronic obstructive pulmonary disease. Preliminary results of a randomized control study

    International Nuclear Information System (INIS)

    Long-acting bronchodilators are recommended as a first-line treatment for chronic obstructive pulmonary disease (COPD), although their effects for postoperative lung cancer patients with COPD are still not well known. A prospective randomized trial was used to examine the efficacy of bronchodilators on postoperative pulmonary function and quality of life (QOL). Twenty lung cancer patients with COPD who had lobectomies were randomized. A control group (n=10) did not receive bronchodilators. An experimental group (n=10) received tiotropium and salmeterol. Patients were divided into two COPD grades: stage I COPD and stage II-III COPD. Results for pulmonary function, 6-minute walking test, and the St. George's Respiratory Questionnaire (SGRQ) were compared. Diaphragmatic motion on dynamic magnetic resonance imaging was also analyzed. The patient demographics were similar in the two groups. Except for pulmonary function results at 2 weeks, no other parameters were significantly different. However, in stage II-III COPD, forced expiratory volume in 1 second, forced vital capacity, inspiratory capacity, the total score of the SGRQ, and diaphragmatic motion in the experimental group (n=5) were significantly better than those in the control group (n=4) at various time points (all P<0.05). The daily inhalation of bronchodilators was effective for maintaining the respiratory function and QOL in lung cancer patients with moderate to severe COPD. (author)

  6. Preliminary Results Of A 600 Joules Small Plasma Focus Device

    Science.gov (United States)

    Lee, S. H.; Yap, S. L.; Wong, C. S.

    2009-07-01

    Preliminary results of a 600 J (3.7 μF, 18 kV) Mather type plasma focus device operated at low pressure will be presented. The discharge is formed between a solid anode with length of 6 cm and six symmetrically and coaxially arranged cathode rods of same lengths. The cathode base is profiled in a knife-edge design and a set of coaxial plasma gun are attached to it in order to initiate the breakdown and enhance the current sheath formation. The experiments have been performed in argon gas under a low pressure condition of several microbars. The discharge current and the voltage across the electrodes during the discharge are measured with high voltage probe and current coil. The current and voltage characteristics are used to determine the possible range of operating pressure that gives good focusing action. At a narrow pressure regime of 9.0±0.5 μbar, focusing action is observed with good reproducibility. Preliminary result of ion beam energy is presented. More work will be carried out to investigate the radiation output.

  7. MR angiography of the abdominal aorta: Preliminary results

    International Nuclear Information System (INIS)

    Flowing blood can be demonstrated as bright signal in MR-imaging resulting in MR-angiography (MRA). This study presents the results of MRA using the 'time of flight'-effect in which projection angiograms along the longitudinal axis were established by a row of 2D-gradient echo (GE) images (FLASH) in breathhold technique. The method was proven in 5 normal volunteers and evaluated against DSA in 21 patients with aortic diseases. The preliminary results demonstrate a satisfactory flow signal in the normally perfused aorta; thus occlusions, stenoses, and aneurysms could be defined clearly. In smaller vessels the signal was still insufficient. Diagnostic problems of vascular overlapping can be solved in most cases by rotating the angiograms, and by additional analysis of individual 2D-GE images. In the present form the quality of MRA is still inferior to that of DSA. (orig.)

  8. Preliminary Results Of LOCA Problem For APR1400 Reactor

    International Nuclear Information System (INIS)

    Several features of NPP with APR1400 nuclear reactor during a loss of coolant accident (LOCA) are investigated in this study. The report describes some main design characteristics of an engineering safety systems of APR1400 and the thermal hydraulic calculation results for steady-state using MARS and RELAP/SCDAPSIM codes. Large Break LOCA accident has been analyzed and evaluated based on acceptable criteria for ECCS given by US NRC. The results from cold leg break LOCA with broken area of 0.0465 m2 in case of high pressure safety injection system (HPSI) failed to operate or 2 and 4 HPSI pumps are activated. The preliminary results of this work is a part of collaboration between INST researchers and KAERI experts in using RELAP tool for safety analysis of NPPs. (author)

  9. Multi-GNSS Orbit and Clock Combination: Preliminary Results

    Science.gov (United States)

    Fritsche, Mathias

    2016-04-01

    In the framework of the Multi-GNSS Experiment (MGEX) a number of Analysis Centers (ACs) extended their software capabilities to process signals from the BeiDou, Galileo, and QZSS systems in addition to the well established systems GPS and GLONASS. Currently, the MGEX product portfolio covers precise satellite orbits and clocks, receiver clocks, signal biases, and Earth rotation parameters generated by the individual ACs. This presentation will provide an overview on the available AC-specific MGEX products. In addition, an introduction to a multi-GNSS orbit and clock combination procedure will be given. Finally, preliminary results from that multi-GNSS combination including a comparison with corresponding operational IGS products will be reported along with a discussion of the results.

  10. Implications of Scheduled ITC Reversion for RPS Compliance: Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Lowder, Travis; Miller, John; O' Shaughnessy, Eric; Heeter, Jenny

    2015-09-14

    This poster presents DRAFT initial results of a forthcoming NREL analysis. The analysis investigates the impacts of the scheduled investment tax credit (ITC) reversion from 30 percent to 10 percent for certain solar photovoltaic projects. Specifically, it considers whether the reversion will result in increased use of alternative compliance payments (ACPs) in lieu of solar renewable energy credits (SRECs) for renewable portfolio standard (RPS) compliance. The analysis models the effect of a 10 percent ITC on power purchase agreement (PPA) prices for non-residential systems in the eight states with solar carve-outs and solar ACPs. Our preliminary results suggest that states will likely install sufficient capacity to meet long-term targets through SRECs rather than ACPs following the ITC reversion. However, the analysis shows that the ITC reversion could affect project economics such that capacity shortfalls in certain states could temporarily increase the use of ACPs. NREL anticipates publishing a full report of this analysis in fall 2015. credits (SRECs) for renewable portfolio standard (RPS) compliance. The analysis models the effect of a 10 percent ITC on power purchase agreement (PPA) prices for non-residential systems in the eight states with solar carve-outs and solar ACPs. Our preliminary results suggest that states will likely install sufficient capacity to meet long-term targets through SRECs rather than ACPs following the ITC reversion. However, the analysis shows that the ITC reversion could affect project economics such that capacity shortfalls in certain states could temporarily increase the use of ACPs. NREL anticipates publishing a full report of this analysis in fall 2015.

  11. Preliminary results on the cryogenic target for FIREX project

    Science.gov (United States)

    Iwamoto, A.; Maekawa, R.; Mito, T.; Okamoto, M.; Motojima, O.; Nakai, M.; Norimatsu, T.; Nagai, K.

    2006-06-01

    Preliminary tests on the cryogenic target for the fast ignition realization experiment (FIREX) project has been conducted. A foam shell method is proposed to realize its target design. A foam target consists of three parts: a foam shell, a conical laser guide and a liquid or gas feeder made of glass. The shell is a hollow sphere (500 μm in diameter) with a uniform and thin foam layer (˜ 20 μm in thickness). Epoxy resin is utilized to assemble the parts into the target. Regarding target fabrication, one of the concerns is the influence on various thermal contractions from the different materials when it is cooled down to cryogenic environment. This paper describes the result on the validity check at cryogenic environment and the demonstration of H{2} liquefaction using a dummy target instead of the foam target.

  12. Preliminary results on epidemiology of Coconut Lethal Yellowing in Ghana

    Directory of Open Access Journals (Sweden)

    Bonnot François

    2009-03-01

    Full Text Available Epidemiological studies are of major importance in understanding the determinants of plant diseases in order to control the risks of their spreading. A research programme on the epidemiology of coconut lethal yellowing, or Cape Saint Paul Wilt Disease (CSPWD, in Ghana was launched in March 2007. The objective was to characterize the distribution and spread of the disease in space and time at various scales, and their relation with the environment. This article presents the general strategy used to evaluate the incidence of CSPWD along with the environmental, ecological and agronomical variables at regional level. A survey was undertaken on 1,166 plots of Coconut Sector Development Project (CSDP planted with Malayan Yellow Dwarf (MYD × Vanuatu Tall (VTT hybrids in Western Region and Central Region. Preliminary results on the distribution of CSPWD and outside variables at regional scale, along with their relations, are given.

  13. Whole-body imaging at 7T: preliminary results.

    Science.gov (United States)

    Vaughan, J Thomas; Snyder, Carl J; DelaBarre, Lance J; Bolan, Patrick J; Tian, Jinfeng; Bolinger, Lizann; Adriany, Gregor; Andersen, Peter; Strupp, John; Ugurbil, Kamil

    2009-01-01

    The objective of this study was to investigate the feasibility of whole-body imaging at 7T. To achieve this objective, new technology and methods were developed. Radio frequency (RF) field distribution and specific absorption rate (SAR) were first explored through numerical modeling. A body coil was then designed and built. Multichannel transmit and receive coils were also developed and implemented. With this new technology in hand, an imaging survey of the "landscape" of the human body at 7T was conducted. Cardiac imaging at 7T appeared to be possible. The potential for breast imaging and spectroscopy was demonstrated. Preliminary results of the first human body imaging at 7T suggest both promise and directions for further development. PMID:19097214

  14. Charge breeder for the SPIRAL1 upgrade: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Maunoury, L., E-mail: maunoury@ganil.fr; Delahaye, P.; Dubois, M.; Bajeat, O.; Frigot, R.; Jeanne, A.; Jardin, P.; Kamalou, O.; Lecomte, P.; Osmond, B.; Peschard, G.; Savalle, A. [GANIL, Bd H. Becquerel BP 55027, F-14076 Caen Cedex 05 (France); Angot, J.; Sole, P.; Lamy, T. [LPSC - Université Grenoble Alpes - CNRS/IN2P3, 53 rue des Martyrs, F-38026 Grenoble Cedex (France); Barton, C. [Department of Physics, University of York, Heslington, York YO10 5DD (United Kingdom)

    2016-02-15

    In the framework of the SPIRAL1 upgrade under progress at the GANIL lab, the charge breeder based on a LPSC Phoenix ECRIS, first tested at ISOLDE has been modified to benefit of the last enhancements of this device from the 1+/n+ community. The modifications mainly concern the 1 + optics, vacuum techniques, and the RF—buffer gas injection into the charge breeder. Prior to its installation in the midst of the low energy beam line of the SPIRAL1 facility, it has been decided to qualify its performances and several operation modes at the test bench of LPSC lab. This contribution shall present preliminary results of experiments conducted at LPSC concerning the 1 + to n+ conversion efficiencies for noble gases as well as for alkali elements and the corresponding transformation times.

  15. Preliminary results and future activities at the GARFIELD apparatus

    Science.gov (United States)

    Gramegna, F.; Mastinu, P. F.; Vannucci, L.; Bruno, M.; D'Agostino, M.; Fiandri, L.; Lanchais, A.; Vannini, G.; Casini, G.; Chiari, M.; Nannini, A.; Bonasera, A.; Cavallaro, S.; Cosmano, A.; Moroni, A.; Ordine, A.; Abbondanno, U.; Milazzo, P. M.; Margagliotti, G. M.

    2002-01-01

    A new apparatus has been designed and built to study reaction mechanisms in the energy regime of the ALPI linear accelerator of the Laboratori Nazionali di Legnaro (E/A = 5 - 20 MeV). In this paper the importance of studying these mechanisms will be underlined, no more as a problem limited to a narrow energy range or a single process, but as a continuous trend from low to high energies and from the physics of stable nuclei to that one regarding instabilities. With this remarks in mind, a first experiment has been performed studying the reaction 32S+58Ni at 11AMeV. Preliminary results show that important information can be derived on multi-body emission, which can contribute to renew the interest in this energy regime.

  16. Preliminary results from LADEE's Neutral Mass Spectrometer (NMS)

    Science.gov (United States)

    Benna, Mehdi; Mahaffy, Paul; Hodges, Richard

    2014-05-01

    The Neutral Mass Spectrometer (NMS) of the Lunar Atmosphere and Dust Environment Explorer (LADEE) Mission is a high sensitivity quadrupole mass spectrometer designed to measure the composition and variability of the tenuous lunar atmosphere. The instrument has been observing the lunar exosphere since 10/17/2013, initially from a near circular 250 km altitude orbit and since 11/11/2013 from an elliptical orbit that reaches to 30-60 km altitude near the sunrise terminator. During its first four months in orbit, the NMS instrument successfully detected exospheric helium, argon and neon and mapped their spatial and temporal variability. Furthermore, the NMS instrument was able to establish new upper limits for many other exospheric species either sputtered or thermally evolved from the lunar surface. This talk will summarize these preliminary results from the NMS measurements.

  17. Preliminary Results of the CASCADE Hidden Sector Photon Search

    CERN Document Server

    Woollett, Nathan; Burt, Graeme; Chattopadhyay, Swapan; Dainton, John; Dexter, Amos; Goudket, Phillipe; Jenkins, Michael; Kalliokoski, Matti; Moss, Andrew; Pattalwar, Shrikant; Thakker, Trina; Williams, Peter

    2015-01-01

    Light shining through a wall experiments can be used to make measurements of photon-WISP couplings. The first stage of the CASCADE experiment at the Cockcroft Institute of Accelerator Science and Technology is intended to be a proof-of-principle experiment utilising standard microwave technologies to make a modular, cryogenic HSP detector to take advantage of future high-power superconducting cavity tests. In these proceedings we will be presenting the preliminary results of the CASCADE LSW experiment showing a peak expected exclusion of $1.10 \\times 10^{-8}$ in the mass range from 1.96$\\mu$eV to 5.38$\\mu$eV, exceeding current limits.

  18. Preliminary on-orbit results of trigger system for DAMPE

    Science.gov (United States)

    Zhang, Yongqiang; Chang, Jin; Guo, Jian hua; Dong, TieKuang; Liu, Yang

    2016-07-01

    The Dark Matter Particle Explorer (DAMPE), Chinese first high energy cosmic ray explorer in space, has been successfully launched at Jiuquan Satellite Launch Center, with the mission of searching dark matter particle. Large energy range for electron/gamma, good energy resolution, and excellent PID ability, make DAMPE to be the most promising detector so far to find the signal of dark matter. DAMPE consists of four sub-detectors: Plastic Scintillation detector, Silicon-Tungsten tracker, BGO calorimeter and Neutron detector. The hit signals generated by the BGO calorimeter and the trigger board (in DAQ) constitute the trigger system of DAMPE, which will generate trigger signals for the four sub-detectors to start data acquisition. The trigger system reduces the trigger rates on orbit from about 1kHz to 70~100Hz, that releases the stress of DAQ transmitting data to ground. In this paper, we will introduce the trigger system of DAMPE, and present some preliminary on-orbit results e.g. trigger efficiency, together with the beam test results at CERN and the simulation results as comparison.

  19. Uranium and thorium recovery in thorianite ore-preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Gaiotte, Joao V.M. [Universidade Federal de Alfenas, Pocos de Caldas, MG (Brazil); Villegas, Raul A.S.; Fukuma, Henrique T., E-mail: rvillegas@cnen.gov.br, E-mail: htfukuma@cnen.gov.br [Comissao Nacional de Energia Nuclear (CNEN), Pocos de Caldas, MG (Brazil). Lab. de Pocos de Caldas

    2011-07-01

    This work presents the preliminary results of the studies aiming to develop a hydrometallurgical process to produce uranium and thorium concentrates from thorianite ore from Amapa State, Brazil. This process comprises two major parts: acid leaching and Th/U recovery using solvent extraction strategies. Thorianite ore has a typical composition of 60 - 70% of thorium, 8 - 10% lead and 7 - 10% uranium. Sulfuric acid leaching operational conditions were defined as follows: acid/ore ratio 7.5 t/t, ore size below 65 mesh (Tyler), 2 hours leaching time and temperature of 100 deg C. Leaching tests results showed that uranium and thorium recovery exceeded 95%, whereas 97% of lead ore content remained in the solid form. Uranium and thorium simultaneous solvent extraction is necessary due to high sulfate concentration in the liquor obtained from leaching, so the Primene JM-T primary anime was used for this extraction step. Aqueous raffinate from extraction containing sulfuric acid was recycled to the leaching step, reducing acid uptake around 60%, to achieve a net sulfuric acid consumption of 3 t/t of ore. Uranium and thorium simultaneous stripping was performed using sodium carbonate solution. In the aqueous stripped it was added sulfuric acid at pH 1.5, followed by a second solvent extraction step using the tertiary amine Alamine 336. The following stripping step was done with a solution of sodium chloride, resulting in a final solution of 23 g L-1 uranium. (author)

  20. InRidge program: Preliminary results from the first cruise

    Digital Repository Service at National Institute of Oceanography (India)

    Mukhopadhyay, R.; Murthy, K.S.R.; Iyer, S.D.; Rao, M.M.M.; Banerjee, R.; Subrahmanyam, A.S.; Shirodkar, P.V.; Ghose, I.

    thicknesses and fresh basaltic nuclei. Preliminary studies indicate a possible mixed hydrothermal and hydrogenous source for these nodules. The water column was also sampled at the Vema and Vityaz transform fault areas....

  1. Preliminary Results from the Large Volume Torsion (LVT) Deformation Apparatus

    Science.gov (United States)

    Cross, A. J.; Couvy, H.; Skemer, P. A.

    2015-12-01

    We present preliminary results from the Large Volume Torsion (LVT) apparatus, currently under development in the rock deformation lab at Washington University in St. Louis. The LVT is designed to deform disk-shaped samples (~4 mm in diameter) in torsion at lower-crustal to upper-mantle pressure and temperature conditions. Conceptually, the LVT complements and is similar in design to the Rotational Drickamer Apparatus (RDA) (Yamakazi & Karato, 2001), which deforms smaller samples at higher pressures. As part of our recent development efforts, benchmarking experiments were performed on Carrara marble. Samples were deformed in torsion at a strain rate of ~5 x 10-5 s-1 to moderate shear strains (γ ≤ 10) under lower crustal conditions (800°C, 2 GPa confining pressure). Microstructural observations from optical microscopy and electron backscatter diffraction (EBSD) show evidence for relict grain elongation and alignment; an increase in calcite twin density; and grain size reduction concurrent with recrystallized grain nucleation. Microstructural observations are comparable to data obtained from previous studies at lower pressure (e.g. Barnhoorn et al., 2004), confirming that the LVT provides reliable microstructural results.

  2. The "SCORPION" experiment onboard the International Space Station. Preliminary results.

    Science.gov (United States)

    Borisov, V; Deshevaya, E; Grachov, E; Grigoryan, O; Tchurilo, I; Tsetlin, V

    2003-01-01

    The "SCORPION" program onboard the Russian Segment (RS) of the International Space Station (ISS) is designed to carry out complex research of the effects of the nar-Earth space parameters on the conditions under which various experiments and operations are being conducted. Special attention in this program was paid to the biological objects onboard the orbital station, e.g. it was found that variation in the number of colony forming units (micromicets and bacteria) correlates with the solar activity and the absorbed dose. The "SCORPION" experiment onboard the RS ISS started in January 2002. It was designed to measure the following parameters inside the space absorbed doses in different places inside the RS ISS, the fluxes of energetic charged particles, neutrons and gamma-quanta; the vectors of the magnetic field and low-frequency electromagnetic waves. At the same time the growth of micromicets on the samples of various materials was studied. The description of the "SCORPION" experiment and the preliminary results obtained onboard the RS ISS in 2002 are presented.

  3. Auroral Spatial Structures Probe Sub-Orbital Mission Preliminary Results

    Science.gov (United States)

    Pratt, J.; Swenson, C.; Martineau, R. J.; Fish, C. S.; Conde, M.; Hampton, D.; Crowley, G.

    2015-12-01

    The NASA Auroral Spatial Structures Probe, 49.002, was launched January 28, 2015 from the Poker Flat Research Range into active aurora over the northern coast of Alaska. The primary objective of this mission was to determine the contribution of small spatial and temporal scale fluctuations of the electric fields to the larger-scale energy deposition processes associated with the aurora. The Auroral Spatial Structures Probe Sub-Orbital Mission consisted of a formation of 7 spacecraft (a main payload with 6 deployable sub-payloads) designed for multiple temporally spaced co-located measurements of electric and magnetic fields in the earth's ionosphere. The mission was able to make observations at a short time scale and small spatial scale convergence that is unobservable by either satellite or ground-based observations. The payloads included magnetometers, electric field double probes, and Langmuir probes as well as a sweeping impedance probe on the main payload. We present here preliminary results from the measurements taken that hint at the underlying spatial structure of the currents and energy deposition in the aurora. The Poynting flux derived from the observations is shown and implications are discussed in terms of the contribution of small spatial scale, rapid temporal scale fluctuations in the currents that deposit energy in the auroral region. Funding provided by NASA Grants NNX11AE23G and NNX13AN20A.

  4. Large co-axial pulse tube preliminary results

    Science.gov (United States)

    Emery, N.; Caughley, A.; Meier, J.; Nation, M.; Tanchon, J.; Trollier, T.; Ravex, A.

    2014-01-01

    We report that Callaghan Innovation, formally known as Industrial Research Ltd (IRL), has designed and built its largest of three high frequency single-stage co-axial pulse tubes, closely coupled to a metal diaphragm pressure wave generator (PWG). The previous pulse tube achieved 110 W of cooling power @ 77 K, with an electrical input power of 3.1 kW from a 90 cc swept volume PWG. The pulse tubes have all been tuned to operate at 50 Hz, with a mean helium working pressure of 2.5 MPa. Sage pulse tube simulation software was used to model the latest pulse tube and predicted 280 W of cooling power @ 77 K. The nominal 250 W cryocooler was designed to be an intermediate step to up-scale pulse tube technology for our 1000 cc swept-volume PWG, to provide liquefaction of gases and cooling for HTS applications. Details of the modeling, design, development and preliminary experimental results are discussed.

  5. SWCX Emission from the Helium Focusing Cone - Preliminary Results

    Science.gov (United States)

    Snowden, S. L.; Kuntz, K. D.; Collier, M. R.

    2008-01-01

    Preliminary results from an XMM-Newton campaign to study solar wind charge exchange (SWCX) emission from the heliospheric focusing cone of interstellar helium are presented. The detections of enhanced O VII and O VIII emission from the cone are at the 2(sigma) and 4(sigma) levels. The solar wind charge exchange (SWCX) emission in the heliosphere not associated with distinct objects (e.g., comets and planets including exospheric material in and near Earth s magnetosheath) is proportional to the flux of the solar wind and the space density of neutral material. The neutral material originates in the interstellar medium (ISM) and passes through the solar system due to the relative motion of the Sun and the ISM. The flow of the neutral material through the solar system is strongly perturbed by the Sun both by gravity and by radiation pressure. Because of the relative radiative scattering cross sections and the effect of solar gravitation the density of interstellar hydrogen near the Sun is reduced while interstellar helium is gravitationally focused. This creates a helium focusing cone downstream of the Sun [e.g., 1, and references therein].

  6. Preliminary results of the XR2-1 experiment

    Energy Technology Data Exchange (ETDEWEB)

    Gauntt, R.O.; Helmick, P.H. [Sandia National Labs., Albuquerque, NM (United States); Humphries, L. [SAIC, Albuquerque, NM (United States)

    1996-03-01

    The XR2-1 (Ex-Reactor) experiment, investigating metallic core-melt relocation in boiling water reactor geometry, was performed on October 12, 1995, following two previous simpler XR1-series tests in August and November of 1993. The XR2-1 test made use of a highly detailed replication of the lower region of the BWR core, including the control blade and channel box structures, fuel rods, fuel canister nosepieces, control blade velocity limiter, and fuel support pieces, in order to investigate a key core melt progression uncertainty for BWR Station Blackout type accidents. The purpose of this experiment program is to examine the behavior of downward-draining molten metallic core materials in a severe reactor accident in a dry BWR core, and to determine conditions under which the molten materials drain out of the core region, or freeze to form blockages in the lower portion of the core. In the event that the draining metallic materials do not form stable blockages in the lower core region, and instead erode the lower core structures such as the lower core plate, then the subsequent core melt progression processes may proceed quite differently than was observed in the TMI-2 accident, with correspondingly different impact on vessel loading and vessel release behavior. The results of the Ex-Reactor tests are preliminary. All of the tests conducted have shown a significant degree of channel box destruction induced by the draining control blade materials. The XR2-1 test further showed that the draining zircaloy melt causes significant disruption of the fuel rod geometry. All of the tests have shown tendencies to form interim blockages as the melts temporarily freeze, but that these blockages re-melt, assisted by eutectic interactions, resulting in the sudden draining of accumulated metallic melt pools.

  7. Varfarin in the complex treatment of antiphospholipid syndrome: preliminary results

    Directory of Open Access Journals (Sweden)

    T M Reshetnyak

    2003-01-01

    Full Text Available Objective. To assess efficacy and tolerance of varfarin in prophylaxis and therapy of thrombotic complications in patients with antiphospholipid syndrome (APS. Methods. 20 pts with APS (5 male and 15 female received varfarin during a year. 8 of them had primary APS (PAPS and 12 -systemic lupus erythematosus with APS (SLE+APS. 2 other pts (I with SLE+APS and I with PAPS received varfarin during the last 4 years. Nobody from 9 pts with PAPS received corticosteroids (CS. In SLE+APS pts CS dose varied from 4 to 20 mg/day and was not increased during follow up. During the study prothrombine time (PT was examined with thromboplastin ( manufactured by Renam having international sensitivity index 1,2 and international normalization relation (INR. Depending on treatment scheme APS pts were divided into 3 groups. Group 1 included 8 pts with INR<2,0, Group 2-7 with INR >3,0, group 3 - 7 pts with INR<2,0 receiving as additional treatment thrombo ASS 100 mg/day and vasonit from 600 to 1200 mg/day. Results. Two pts with INR = 1,8 had thrombosis recurrence (due to leg thrombophlebitis. There were no recurrences in other groups. 2 from 22 pts had "large" bleedings. "Small" bleedings episodes were noted in 7 from 22 pts. Largely that were subcutaneous bleedings (in 4 pts no more than 5 cm of size. Two pts receiving varfarin with INR 1,8 and 2,4 had renal colic. Conclusion. Our preliminary results prove the necessity of inclusion of varfarin in the treatment of pts with APS and thrombosis but intensive anticoagulant effect is not always desired.

  8. Preliminary Characterization Results from the DebriSat Project

    Science.gov (United States)

    Rivero, M.; Shiotani, B.; Kleespies, J.; Toledo-Burdett, R.; Moraguez, M.; Carrasquila, M.; Fitz-Coy, N.; Liou, J.-C.; Sorge, M.; Huynh, T.

    2016-01-01

    preliminary results presented. Additionally, lessons learned from the implemented automations and their impacts on the integrity of the results are discussed.

  9. Intraspecific variability of European larch for wood properties: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Paques, L.E.; Rozenberg, P. [Institut National de Recherches Agronomiques (INRA), 45 - Olivet (France). Station d`Amelioration des Arbres Forestiers

    1995-12-31

    Wood properties of several natural populations of European larch (Larix decidua Mill) were determined from samples collected in one replicate of the II. International IUFRO provenance experiment, planted in Brittany in 1959. According to provenances, proportion of heartwood ranges from 35 to 58% of basal area, basic density from 442 to 505 g/dm{sup 3} and Young modulus of elasticity from 8474 to 14522 MPa. Positive correlations between girth and heartwood proportion and between wood density and modulus of elasticity but negative correlations between ring width and both density and MOE have been found both at the individual and at the population levels. Variability between and within provenances is high for two major traits (proportion of heartwood and Young modulus of elasticity) for which a SW - NE gradient is shown. For wood density parameters including pilodyn, a greater homogeneity is observed. Besides a now largely recognized superiority for growth traits, Central European populations from the Sudetan Mountains and Central Poland would also produce wood with better properties. On the reverse, Alpine populations from the French Alps growing at low elevations have a slower growth, a denser wood with less heartwood and less strength. Used as a control, the hybrid larch origin (Larix x eurolepis) represents the best compromise for wood properties with the highest strength but an average wood density and one of the highest proportion of heartwood. These preliminary results must be confirmed from a larger set of provenances and completed with other major wood properties such as durability and shrinkage. 17 refs, 2 figs, 6 tabs

  10. COSMIC EVOLUTION OF DUST IN GALAXIES: METHODS AND PRELIMINARY RESULTS

    Energy Technology Data Exchange (ETDEWEB)

    Bekki, Kenji [ICRAR, M468, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009 (Australia)

    2015-02-01

    We investigate the redshift (z) evolution of dust mass and abundance, their dependences on initial conditions of galaxy formation, and physical correlations between dust, gas, and stellar contents at different z based on our original chemodynamical simulations of galaxy formation with dust growth and destruction. In this preliminary investigation, we first determine the reasonable ranges of the most important two parameters for dust evolution, i.e., the timescales of dust growth and destruction, by comparing the observed and simulated dust mass and abundances and molecular hydrogen (H{sub 2}) content of the Galaxy. We then investigate the z-evolution of dust-to-gas ratios (D), H{sub 2} gas fraction (f{sub H{sub 2}}), and gas-phase chemical abundances (e.g., A {sub O} = 12 + log (O/H)) in the simulated disk and dwarf galaxies. The principal results are as follows. Both D and f{sub H{sub 2}} can rapidly increase during the early dissipative formation of galactic disks (z ∼ 2-3), and the z-evolution of these depends on initial mass densities, spin parameters, and masses of galaxies. The observed A {sub O}-D relation can be qualitatively reproduced, but the simulated dispersion of D at a given A {sub O} is smaller. The simulated galaxies with larger total dust masses show larger H{sub 2} and stellar masses and higher f{sub H{sub 2}}. Disk galaxies show negative radial gradients of D and the gradients are steeper for more massive galaxies. The observed evolution of dust masses and dust-to-stellar-mass ratios between z = 0 and 0.4 cannot be reproduced so well by the simulated disks. Very extended dusty gaseous halos can be formed during hierarchical buildup of disk galaxies. Dust-to-metal ratios (i.e., dust-depletion levels) are different within a single galaxy and between different galaxies at different z.

  11. Magnetic Resonance Elastography of Liver Tumors- Preliminary Results

    Science.gov (United States)

    Venkatesh, Sudhakar K; Yin, Meng; Glockner, James F; Takahashi, Naoki; Araoz, Philip A; Talwalkar, Jayant A; Ehman, Richard L

    2010-01-01

    Aim To evaluate the potential value of magnetic resonance elastography (MRE) for characterizing solid liver tumors. Materials and Methods Forty-four liver tumors (metastases-14, hepatocellular carcinoma- 12, hemangioma-9, cholangiocarcinoma-5, focal nodular hyperplasia-3, and hepatic adenoma-1) were evaluated with MRE. MRE was performed on a 1.5 T scanner with a modified phase-contrast, gradient echo sequence to collect axial wave images sensitized along the through-plane motion direction. The tumors were identified in T2-, T1-weighted and gadolinium enhanced T1-weighted images and the MRE images were obtained through the tumor. A stiffness map (elastogram) was generated by an automated process using an inversion algorithm. The mean shear stiffness of the tumor was calculated using a manually specified region of interest placed over the tumor in the stiffness map. The stiffness value of non-tumor bearing hepatic parenchyma was also calculated. Statistical analysis was performed on the stiffness values for differentiation between normal liver, fibrotic liver, benign tumors and malignant tumors. Results Malignant liver tumors had significantly higher mean shear stiffness than benign tumors, fibrotic liver and normal liver (10.1kPa vs. 2.7kpa (p<0.001), vs. 5.9kPa (p<0.001) and vs. 2.3kPa (p<0.001) respectively). Fibrotic livers had stiffness values overlapping both the benign and malignant tumors. Cut-off values of 5kPa accurately differentiate malignant tumors from benign tumors and normal liver parenchyma in this preliminary investigation. Conclusions MR elastography is a promising, non-invasive technique for assessing solid liver tumors. MRE may provide new, quantitative tissue characterization parameters for differentiating benign and malignant liver tumors. PMID:18492904

  12. A Preliminary Analysis of Non-small Cell Lung Cancer Biomarkers in Serum

    Institute of Scientific and Technical Information of China (English)

    XUE-YUAN XIAO; YING TANG; XIU-PING WEI; DA-CHENG HE

    2003-01-01

    Objective To identify potential serum biomarkers that could be used to discriminate lungcancers from normal. Methods Proteomic spectra of twenty-eight serum samples from patientswith non-small cell lung cancer and twelve from normal individuals were generated by SELDI(Surfaced Enhanced Laser Desorption/Ionization) Mass Spectrometry. Anion-exchange columns wereused to fractionate the sera into 6 designated pH groups. Two different types of protein chip arrays,IMAC-Cu and WCX2, were employed. Samples were examined in PBSII Protein Chip Reader(Ciphergen Biosystem Inc) and the discriminatory profiling between cancer and normal samples wasanalyzed with Biomarker Pattern software. Results Five distinct potential lung cancer biomarkerswith higher sensitivity and specificity were found, with four common biomarkers in both IMAC-Cuand WCX2 chip; the remaining biomarker occurred only in WCX2 chip. Two biomarkers wereup-regulated while three biomarkers were down-regulated in the serum samples from patients withnon-small cell lung cancer. The sensitivities provided by the individual biomarkers were 75%-96.43%and specificities were 75%-100%. Conclusions The preliminary results suggest that serum is acapable resource for detecting specific non-small cell lung cancer biomarkers. SELDI massspectrometry is a useful tool for the detection and identification of new potential biomarker ofnon-small cell lung cancer in serum.

  13. Mycodiversity in marine sediments contaminated by heavy metals: preliminary results

    Science.gov (United States)

    Zotti, Mirca; Carbone, Cristina; Cecchi, Grazia; Consani, Sirio; Cutroneo, Laura; Di Piazza, Simone; Gabutto, Giacomo; Greco, Giuseppe; Vagge, Greta; Capello, Marco

    2016-04-01

    .6 CFU per gram of sediments. The maximum value of 11 CFU g-1 has been recorded in two stations (off the Sestri Levante Tombolo), while the minimum value has been recorded closer to the coast. As concern qualitative results, the most recurrent genera are Aspergillus and Penicillium. These data confirm the occurrence of a mycobiota in these heavy metal contaminated sediments. Our preliminary results are a first contribution to the knowledge of presence of microfungi in marine sediments, and propel us to increase our research in order to find out new organisms for bioremediation purpose.

  14. Monitoring of a slope affected by shallow landslides: preliminary results

    Science.gov (United States)

    Meisina, Claudia; Zizioli, Davide; Bordoni, Massimiliano; Valentino, Roberto; Bittelli, Marco; Chersich, Silvia

    2013-04-01

    pluviometer, a thermo-hygrometer, a barometer, a sonic anemometer and a net radiometer. Six TDR probes (Time Domain Reflectometer) are installed at 0.2, 0.4, 0.6, 1, 1.2, 1.4 meters from ground level to measure the soil volumetric water content. To measure soil matric suction three tensiometers and three heat dissipation sensors are installed at 0.2, 0.6, 1.2 meters from ground level. The data are collected by a CR1000 datalogger (Campbell Sci. Inc.) every 10 minutes. In this work preliminary results obtained from 12 months of monitoring are presented: emphasis is given to the response of the cover materials after dry and wet periods in terms of soil water content and matric potential. These results will be linked to determine the hydro-geotechnical processes that could predispose the triggering of shallow landslides.

  15. Gene Expression Profiling in Hereditary, BRCA1-linked Breast Cancer: Preliminary Report

    Directory of Open Access Journals (Sweden)

    Dudaladava Volha

    2006-01-01

    Full Text Available Abstract Global analysis of gene expression by DNA microarrays is nowadays a widely used tool, especially relevant for cancer research. It helps the understanding of complex biology of cancer tissue, allows identification of novel molecular markers, reveals previously unknown molecular subtypes of cancer that differ by clinical features like drug susceptibility or general prognosis. Our aim was to compare gene expression profiles in breast cancer that develop against a background of inherited predisposing mutations versus sporadic breast cancer. In this preliminary study we analysed seven hereditary, BRCA1 mutation-linked breast cancer tissues and seven sporadic cases that were carefully matched by histopathology and ER status. Additionally, we analysed 6 samples of normal breast tissue. We found that while the difference in gene expression profiles between tumour tissue and normal breast can be easily recognized by unsupervised algorithms, the difference between those two types of tumours is more discrete. However, by supervised methods of data analysis, we were able to select a set of genes that may differentiate between hereditary and sporadic tumours. The most significant difference concerns genes that code for proteins engaged in regulation of transcription, cellular metabolism, signalling, proliferation and cell death. Microarray results for chosen genes (TOB1, SEPHS2 were validated by real-time RT-PCR.

  16. Anisotropy of Pore Structure and Permeability in Granite: Preliminary Results

    Science.gov (United States)

    Onishi, C. T.; Shimizu, I.; Mizoguchi, K.; Uehara, S.; Shimamoto, T.

    2001-12-01

    of 25- 200 MPa, with pore pressure kept around 20 MPa. Preliminary results indicate relatively high permeability for undeformed biotite granite, about 10-16m2 at the initial confining pressure (Pc=30MPa), and with a gradual decrease to 10-17m2 at the highest Pc(=198MPa). The fractured sample with cataclastic seams has lower permeability (in the order of 10-17 to 10-18m2) possibly due to crack sealing by hydrothermal activities.

  17. IART® (Intra-Operative Avidination for Radionuclide Therapy) for accelerated radiotherapy in breast cancer patients. Technical aspects and preliminary results of a phase II study with 90Y-labelled biotin

    OpenAIRE

    Paganelli, G.; De Cicco, C; M. E. Ferrari; McVie, G.; Pagani, G; Leonardi, M C; Cremonesi, M.; Ferrari, A.; Pacifici, M.; Di Dia, A; Botta, F; De Santis, R; Galimberti, V.; Luini, A.; Orecchia, R.

    2010-01-01

    Background: Breast conserving surgery (BCS) plus external beam radiotherapy (EBRT) is considered the standard treatment for early breast cancer. We have investigated the possibility of irradiating the residual gland, using an innovative nuclear medicine approach named IART® (Intra-operative Avidination for Radionuclide Therapy). Aim: The objective of this study was to determine the optimal dose of avidin with a fixed activity (3.7 GBq) of 90Y-biotin, in order to provide a boost of 20 Gy, foll...

  18. Preliminary Results from SCEC Earthquake Simulator Comparison Project

    Science.gov (United States)

    Tullis, T. E.; Barall, M.; Richards-Dinger, K. B.; Ward, S. N.; Heien, E.; Zielke, O.; Pollitz, F. F.; Dieterich, J. H.; Rundle, J. B.; Yikilmaz, M. B.; Turcotte, D. L.; Kellogg, L. H.; Field, E. H.

    2010-12-01

    realistic fault geometies and slip rates taken from California, excluding the Cascadia subduction zone. In order to make as close comparisons between the simulators as possible we have developed shared data formats for both input and output and a growing set of tools that can be used to make statistical comparisons between the simulator outputs. To date all five simulators have run a Northern California fault model and are in various stages of working on an All California fault model. The plan in the near future is to run them on the UCERF2 fault model. Initial comparisons show significant differences among the simulators and some differences from observed earthquake statistics. However, it is too early in the process to infer too much from these preliminary results. For example, the differences in how each simulator treats fault friction means that they may each need to use values for the assumed stress drops that are better tuned to their approach than are the common values used in the first comparison.

  19. Preliminary results of the PREFER FP7 Project

    Science.gov (United States)

    Fusilli, Lorenzo; Laneve, Giovanni; De Bonis, Roberto; Sebastian, Ana; Ferrucci, Fabrizio; Oliveira, Sandra

    2014-05-01

    The need to improve the information and intelligence support for forest fire prevention is widely recognized. Fire prevention is still the most cost-effective strategy when compared to firefighting and extinguishing that are costly, local, and triggered only in response to already ongoing crises. PREFER project, funded under the EU FP7 (G.A. 312931), intends to contribute at responding to such a pragmatic need of southern Europe's forests by: providing timely information products based on the exploitation of all available spacecraft sensors, offering a portfolio of products focused on pre- and post-crisis forest fire emergency, suitable for the users in the different countries of the European Mediterranean area. The PREFER Service portfolio consists of two main services: 1. Information Support to Fire Preparedness/Prevention Phase" (ISP) Service 2. Information Support to Fire Recovery/Reconstruction Phase" (ISR) Service This service is already at an advanced stage having completed the first year of activity. During this time several products have been consolidated: seasonal fuel maps; daily and seasonal fire hazard maps; seasonal risk maps; prescribed fire maps. This paper aims at presenting the preliminary results of the research activity carried out in the framework of the PREFER project, focusing, in particular, on these recalled above. As for Fire Risk and Hazard assessment, many indexes have been developed in the last years. Hardly any of them uses data derived from satellite images. The FPI index is an exception to this rule which, in addition, makes use of meteorological data. In spite of being a very complete index, the FPI still allows room for improvement which justify the interest of PREFER in it. PREFER's innovative approach to FPI will allow taking into account the effect of solar illumination conditions in determining the humidity present in the dead vegetation, and therefore its proneness to burn. PREFER innovation also focus in allowing the index to

  20. Metabolic syndrome in rheumatoid arthritis: role of adiponectin (preliminary results

    Directory of Open Access Journals (Sweden)

    Yulia Nikolaevna Gorbunova

    2013-01-01

    were encountered with the same frequency in early- and end-stage RA. The early RA group showed a correlation between SDAI (r = -0.34, body mass index (r = -0.41, high-density lipoprotein cholesterol (r = 0.33, erythrocyte sedimentation rate (r =-0.35, and adiponectin. The >2-year RA group displayed no relationship between adipokins, activity markers, and metabolic disturbances. Conclusion. The preliminary results suggest the high rate of MS in patients with a high level of early RA disease activity untreated with disease-modifying antirheumatic drugs, thus determining the high risk of CVEs just at disease onset. The role of adiponectin in the development of MS, CVEs in rheumatic diseases remains to be solved, which is the subject of further investigations. It is possible that normalization of adiponectin concentrations may promote reductions in the incidence of CVD, mortality rates due to atherosclerosis-induced CVEs, and the prevalence of MS and insulin resistance.

  1. Safety of a 3-weekly schedule of carboplatin plus pegylated liposomal doxorubicin as first line chemotherapy in patients with ovarian cancer: preliminary results of the MITO-2 randomized trial

    International Nuclear Information System (INIS)

    The MITO-2 (Multicentre Italian Trials in Ovarian cancer) study is a randomized phase III trial comparing carboplatin plus paclitaxel to carboplatin plus pegylated liposomal doxorubicin in first-line chemotherapy of patients with ovarian cancer. Due to the paucity of published phase I data on the 3-weekly experimental schedule used, an early safety analysis was planned. Patients with ovarian cancer (stage Ic-IV), aged < 75 years, ECOG performance status ≤ 2, were randomized to carboplatin AUC 5 plus paclitaxel 175 mg/m2, every 3 weeks or to carboplatin AUC 5 plus pegylated liposomal doxorubicin 30 mg/m2, every 3 weeks. Treatment was planned for 6 cycles. Toxicity was coded according to the NCI-CTC version 2.0. The pre-planned safety analysis was performed in July 2004. Data from the first 50 patients treated with carboplatin plus pegylated liposomal doxorubicin were evaluated. Median age was 60 years (range 34–75). Forty-three patients (86%) completed 6 cycles. Two thirds of the patients had at least one cycle delayed due to toxicity, but 63% of the cycles were administered on time. In most cases the reason for chemotherapy delay was neutropenia or other hematological toxicity. No delay due to palmar-plantar erythrodysesthesia (PPE) was recorded. No toxic death was recorded. Reported hematological toxicities were: grade (G) 3 anemia 16%, G3/G4 neutropenia 36% and 10% respectively, G3/4 thrombocytopenia 22% and 4% respectively. Non-haematological toxicity was infrequent: pulmonary G1 6%, heart rhythm G1 4%, liver toxicity G1 6%, G2 4% and G3 2%. Complete hair loss was reported in 6% of patients, and G1 neuropathy in 2%. PPE was recorded in 14% of the cases (G1 10%, G2 2%, G3 2%). This safety analysis shows that the adopted schedule of carboplatin plus pegylated liposomal doxorubicin given every 3 weeks is feasible as first line treatment in ovarian cancer patients, although 37% of the cycles were delayed due to haematological toxicity. Toxicities that are common

  2. Treatment of colorectal cancer - distance results

    Directory of Open Access Journals (Sweden)

    L. Vasile

    2012-01-01

    Full Text Available Significant advances about carcinogenesis and natural history of colorectal cancer (CRC,particularly the establishment of filiations polyp-cancer, are important objectives for a new approach to diagnosis of this disease. Decade 1990-2000 was the decade of CRC detection and prevention, but the decade 2000-2010 is the period of application of new diagnostic and therapeutic concepts. The aim of this study was to highlight the epidemiological,clinical,therapeutic, evolution and prognosis aspects of this cancer at five years after treatment. The research was based on examination of the computerized system of C.E.U.H. of Craiova, observation sheets, operation protocols and anatomic-pathological results, from which we identified from January 2003 until December 2005 a number of 134 patients with CRC investigated, treated and followed completely. At study end (01.07.2010 we noted that 51 of 134 resected patients (38.05% were alive. The median survival time to the entire group of 134 caseswas 44.35 + / -29.94 months. Factors that contribute to a favorable prognosis in CRC are female gender, urban environement origin, ounger than 50 years, the absence of disease or complications associated with neoplasia, colic locations, elective surgery, vegetant and papillary forms, G1 and G2 grading and the disease diagnosed in TMN stages I and II.

  3. Computer-aided hepatic tumour ablation requirements and preliminary results

    CERN Document Server

    Voirin, D; Amavizca, M; Letoublon, C; Troccaz, J; Voirin, David; Payan, Yohan; Amavizca, Miriam; Letoublon, Christian; Troccaz, Jocelyne

    2002-01-01

    Surgical resection of hepatic tumours is not always possible, since it depends on different factors, among which their location inside the liver functional segments. Alternative techniques consist in local use of chemical or physical agents to destroy the tumour. Radio frequency and cryosurgical ablations are examples of such alternative techniques that may be performed percutaneously. This requires a precise localisation of the tumour placement during ablation. Computer-assisted surgery tools may be used in conjunction with these new ablation techniques to improve the therapeutic efficiency, whilst they benefit from minimal invasiveness. This paper introduces the principles of a system for computer-assisted hepatic tumour ablation and describes preliminary experiments focusing on data registration evaluation. To keep close to conventional protocols, we consider registration of pre-operative CT or MRI data to intra-operative echographic data.

  4. Results of preliminary Microwave Multi-Applications Payload (MMAP) study

    Science.gov (United States)

    1975-01-01

    A preliminary feasibility study of the microwave multi-applications payload (MMAP) system for the Spacelab has been carried out. The initial objectives of this study have been to determine the minimum equipment requirements of the MMAP and the feasibility of placing the numerous large aperture antennas in the Spacelab. The study was begun by reviewing the experimental objectives and techniques and determining areas of commonality. Emphasis was given to the determination of common RF equipment requirements. These requirementers were considered after agreement among the experiments had been reached on limiting the number of frequencies to be used in the system. This was done so that the number of antennas, transmitters, and receivers could be minimized. The electronics system block diagram and the antenna configurations were considered in some details. It was concluded that the MMAP is feasible and can be an economical method of achieving a large number of experimental goals.

  5. Preliminary Results on Lunar Interior Properties from the GRAIL Mission

    Science.gov (United States)

    Williams, James G.; Konopliv, Alexander S.; Asmar, Sami W.; Lemoine, H. Jay; Melosh, H. Jay; Neumann, Gregory A.; Phillips, Roger J.; Smith, David E.; Solomon, Sean C.; Watkins, Michael M.; Wieczorek, Mark A.; Zuber, Maria T.; Andrews-Hanna, Jeffrey C.; Head, James W.; Kiefer, Walter S.; Matsuyama, Isamu; McGovern, Patrick J.; Nimmo, Francis; Weber, Renee C.; Boggs, D. H.; Goossens, Sander J.; Kruizinga, Gerhard L.; Mazarico, Erwan; Park, Ryan S.; Yuan, Dah-Ning

    2013-01-01

    The Gravity Recovery and Interior Laboratory (GRAIL) mission has provided lunar gravity with unprecedented accuracy and resolution. GRAIL has produced a high-resolution map of the lunar gravity field while also determining tidal response. We present the latest gravity field solution and its preliminary implications for the Moon's interior structure, exploring properties such as the mean density, moment of inertia of the solid Moon, and tidal potential Love number k2. Lunar structure includes a thin crust, a deep mantle, a fluid core, and a suspected solid inner core. An accurate Love number mainly improves knowledge of the fluid core and deep mantle. In the future GRAIL will search for evidence of tidal dissipation and a solid inner core.

  6. Seismic Hazard Maps for the Maltese Archipelago: Preliminary Results

    Science.gov (United States)

    D'Amico, S.; Panzera, F.; Galea, P. M.

    2013-12-01

    The Maltese islands form an archipelago of three major islands lying in the Sicily channel at about 140 km south of Sicily and 300 km north of Libya. So far very few investigations have been carried out on seismicity around the Maltese islands and no maps of seismic hazard for the archipelago are available. Assessing the seismic hazard for the region is currently of prime interest for the near-future development of industrial and touristic facilities as well as for urban expansion. A culture of seismic risk awareness has never really been developed in the country, and the public perception is that the islands are relatively safe, and that any earthquake phenomena are mild and infrequent. However, the Archipelago has been struck by several moderate/large events. Although recent constructions of a certain structural and strategic importance have been built according to high engineering standards, the same probably cannot be said for all residential buildings, many higher than 3 storeys, which have mushroomed rapidly in recent years. Such buildings are mostly of unreinforced masonry, with heavy concrete floor slabs, which are known to be highly vulnerable to even moderate ground shaking. We can surely state that in this context planning and design should be based on available national hazard maps. Unfortunately, these kinds of maps are not available for the Maltese islands. In this paper we attempt to compute a first and preliminary probabilistic seismic hazard assessment of the Maltese islands in terms of Peak Ground Acceleration (PGA) and Spectral Acceleration (SA) at different periods. Seismic hazard has been computed using the Esteva-Cornell (1968) approach which is the most widely utilized probabilistic method. It is a zone-dependent approach: seismotectonic and geological data are used coupled with earthquake catalogues to identify seismogenic zones within which earthquakes occur at certain rates. Therefore the earthquake catalogues can be reduced to the

  7. Chemopreventive Effects of Morindia Citrifolia Juice (noni on Experimental Breast Cancer in Rats: Preliminary Study

    Directory of Open Access Journals (Sweden)

    Ana Milena Serrano Contreras

    2014-06-01

    Full Text Available This study determines the effect of Morindia citrifolia juice (Tahitian Noni® in the development of breast cancer induced by carcinogen agent 7.12-dimethylbenzanthracene (DMBA in rats. For this purpose, the breast cancer induction model 1.7-DMBA was used on Spraguey Dawley nulliparous rats of 35 days of age, randomly divided into three groups: group 1 control, which received no treatment, and groups 2 and 3, induced with DMBA at a dose of 55 mg/kg. The latter received a dose of noni juice of 4 ml/kg per day for 90 days. The results showed that a significant percentage (83.33% of the rats from the group induced with DMBA not treated with noni juice developed palpable breast tumors ( ≤ 2 cm of the ductal carcinoma in situ type and atypical ductal hyperplasia, compared to the other groups that did not develop any kind of tumors. In addition, it was found that rats that developed breast cancer had a lower weight gain and significantly increased water consumption (p < 0.05 compared to the other two groups. The results of the hematological and biochemical parameters showed no significant changes between groups. Histopathological changes compatible with liver toxicity were found in rats treated with noni juice. In conclusion, it was found in this preliminary study that noni juice has positive effects in modulating the development of breast cancer induced by DMBA.

  8. Genesis Silicon Carbide Concentrator Target 60003 Preliminary Ellipsometry Mapping Results

    Science.gov (United States)

    Calaway, M. J.; Rodriquez, M. C.; Stansbery, E. K.

    2007-01-01

    The Genesis concentrator was custom designed to focus solar wind ions primarily for terrestrial isotopic analysis of O-17/O-16 and O-18/O-16 to +/-1%, N-15/N-14 to +/-1%, and secondarily to conduct elemental and isotopic analysis of Li, Be, and B. The circular 6.2 cm diameter concentrator target holder was comprised of four quadrants of highly pure semiconductor materials that included one amorphous diamond-like carbon, one C-13 diamond, and two silicon carbide (SiC). The amorphous diamond-like carbon quadrant was fractured upon impact at Utah Test and Training Range (UTTR), but the remaining three quadrants survived fully intact and all four quadrants hold an important collection of solar wind. The quadrants were removed from the target holder at NASA Johnso n Space Center Genesis Curation Laboratory in April 2005, and have been housed in stainless steel containers under continual nitrogen purge since time of disintegration. In preparation for allocation of a silicon carbide target for oxygen isotope analyses at UCLA, the two SiC targets were photographed for preliminary inspection of macro particle contamination from the hard non-nominal landing as well as characterized by spectroscopic ellipsometry to evaluate thin film contamination. This report is focused on Genesis SiC target sample number 60003.

  9. Smokers' expectancies for abstinence: preliminary results from focus groups.

    Science.gov (United States)

    Hendricks, Peter S; Wood, Sabrina B; Hall, Sharon M

    2009-06-01

    Smokers' expectancies regarding the effects of cigarette use are powerful predictors of smoking motivation and behavior. However, studies have not investigated the consequences that smokers expect when they attempt to quit smoking: abstinence-related expectancies. The primary goal of this qualitative study was to gain initial insight into smokers' expectancies for abstinence. Eight focus groups were conducted with 30 smokers diverse with respect to age, gender, and ethnoracial background. Content analyses indicated that smokers anticipate a variety of outcomes from abstinence. The most frequently reported expectancies included pharmacologic withdrawal symptoms, behavioral withdrawal symptoms, decreased monetary expense, and immediate improvement of certain aspects of physical functioning and health. Additional expectancies concerned weight gain, improved attractiveness, enhanced social functioning/self-esteem, long-term health outcomes, and loss of relationships. Finally, a number of relatively unheralded expectancies were revealed. These involved nicotine replacement therapy effectiveness, alcohol and other drug use, cue reactivity, cessation-related social support, aversion to smoking, and "political process" implications. This study provides a preliminary step in understanding smokers' expectancies for abstinence from cigarettes. PMID:19586157

  10. Rayleigh to Compton ratio scatter tomography applied to breast cancer diagnosis: A preliminary computational study

    International Nuclear Information System (INIS)

    In the present work, a tomographic technique based on Rayleigh to Compton scattering ratio (R/C) was studied using computational simulation in order to assess its application to breast cancer diagnosis. In this preliminary study, some parameters that affect the image quality were evaluated, such as: (i) energy beam, (ii) size and glandularity of the breast, and (iii) statistical count noise. The results showed that the R/C contrast increases with increasing photon energy and decreases with increasing glandularity of the sample. The statistical noise showed to be a significant parameter, although the quality of the obtained images was acceptable for a considerable range of noise level. The preliminary results suggest that the R/C tomographic technique has a potential of being applied as a complementary tool in the breast cancer diagnostic. - Highlights: ► A tomographic technique based on Rayleigh to Compton scattering ratio is proposed in order to study breast tissues. ► The Rayleigh to Compton scattering ratio technique is compared with conventional transmission technique. ► The influence of experimental parameters (energy, sample, detection system) is studied

  11. Preliminary Cluster Size and Efficiencies results of CMS RPC at GIF++

    CERN Document Server

    Gonzalez Blanco Gonzalez, Genoveva

    2016-01-01

    A brief description and first preliminary results of the Efficiencies and Cluster Size measurements of the CMS Resistive Plate Chambers, will be presented inside the Gamma Irradiation Facility GIF++ at CERN. Preliminary studies that sets the base performance measurements of CMS RPC for starting aging studies.

  12. 78 FR 48147 - Polyethylene Terephthalate Film, Sheet, and Strip From India: Preliminary Results of...

    Science.gov (United States)

    2013-08-07

    ... International Trade Administration Polyethylene Terephthalate Film, Sheet, and Strip From India: Preliminary... film, sheet and strip (PET film) from India for the period of review (POR) January 1, 2011, through... Strip from India (Preliminary Decision Memorandum), dated concurrently with these results and...

  13. Preliminary Results on Sediment Sorting Under Intense Bedload Transport

    Science.gov (United States)

    Hernandez Moreira, R. R.; Vautin, D.; Mathews, S. L.; Kuprenas, R.; Viparelli, E.

    2014-12-01

    Previous experiments show that parallel-laminated deposits are emplaced under upper plane bed regime by the migration of small-amplitude, long-wavelength bedforms. The present research focuses on how sediment is sorted under upper plane bed and sheet flow transport regimes, and whether parallel-lamination is inhibited during sheet flow transport. The problem of studying the sorting of sediment under so intense transport conditions is plagued by the uncertainties related to flow resistances and bedload transport rates. We simplify the problem by first running the experiments with uniform sediment, to establish a baseline that will aid in the design of the experiments with poorly sorted material. We are running experiments at the Hydraulics Laboratory of the Department of Civil and Environmental Engineering at the University of South Carolina in Columbia, in a unidirectional sediment-feed flume, 9 meters long by 0.2 meters wide, of which 7 meters are used as test section. During the experiments, water surface and bed elevations are periodically measured to characterize the global parameters of the flow, e.g. mean flow velocity and bed shear stress. When the flow and the sediment transport reach conditions of mobile bed equilibrium, bed elevation fluctuations are measured with ultrasonic transducer systems at six fixed locations. Channel bed aggradation is then induced by slowly raising the tail gate of the flume such that there is no change in transport regime, as confirmed by additional measurements of water surface and bed elevation and bed elevation fluctuations. Preliminary observations under upper plane bed regime show the formation of the small-amplitude and long-wavelength bedforms, as well as hints of parallel lamination in the deposits. In the near future we aim to achieve sheet flow transport conditions with both uniform and non-uniform grain size distributions to look at the internal structure of the emplaced deposit.

  14. Observations of liver cancer cells in scanning probe acoustic microscope: a preliminary study

    Science.gov (United States)

    Chen, Xiaohui; Fang, Xiaoyue; Xi, Qing; Guo, Hua; Zhang, Ning; Ding, Mingyue

    2016-04-01

    Scanning probe acoustic microscope (SPAM) can be used to acquire the morphology image as well as the non-destructive internal structures acoustic image. However, the observations of the morphology image as well as the internal structures acoustic image of liver cancer cells in SPAM are few. In this paper, we cultured 4 different types of liver cancer cells on the silicon wafer and coverslip to observe their morphology images as well as acoustic images in SPAM, and made a preliminary study of the 8 types of cells specimens (hereinafter referred to as the silicon specimens and coverslips specimens). The experimental measurement results showed that some cellular pseudopodium were observed in the morphology images of the coverslip specimens while no such cellular pseupodium were appeared in the morphology images of the silicon specimens, which concluded that the living liver cancer cells were less likely to grow on the silicon wafer. SPAM provides a rapid and sensitive visual method for studying the morphology and internal structures of the cancer cells. The proposed method can be also used to obtain the morphology and internal information in both solid and soft material wafers, such as silicon and cells, with the resolution of nanometer scale.

  15. Microbial extremophiles from the 2008 Schirmacher Oasis Expedition: preliminary results

    Science.gov (United States)

    Hoover, Richard B.; Pikuta, Elena V.; Townsend, Alisa; Anthony, Joshua; Guisler, Melissa; McDaniel, Jasmine; Bej, Asim; Storrie-Lombardi, Michael

    2008-08-01

    Among the most interesting targets for Astrobiology research are the polar ice caps and the permafrost of Mars and the ice and liquid water bodies that may lie beneath the frozen crusts of comets, the icy moons of Jupiter (Europa, Io and Ganymede) and Saturn (Titan and Enceladus). The permanently ice-covered lakes of Antarctica, such as Lake Vostok and Lake Untersee, provide some of the best terrestrial analogues for these targets. The 2008 International Tawani Schirmacher Oasis/Lake Untersee Expeditions have been organized to conduct studies of novel microbial extremophiles and investigate the biodiversity of the glaciers and ice-covered lakes of Dronning Maud Land, East Antarctica. This paper describes the preliminary analysis of the anaerobic microbial extremophiles isolated from samples collected during the 2008 International Schirmacher Oasis Antarctica Reconnaissance Expedition. These samples showed great diversity of psychrophlic and psychrotolerant bacteria. Six new anaerobic strains have been isolated in pure cultures and partially characterized. Two of them (strains ARHSd-7G and ARHSd-9G) were isolated from a small tidal pool near the colony of African Penguins Spheniscus demersus. Strain ARHSd-7G was isolated on mineral anaerobic medium with 3 % NaCl, pH 7 and D-glucose, it has motile, vibrion shape cells, and is Gram variable. Strain ARHSd-9G grew on anaerobic, alkaline medium with pH 9 and 1 % NaCl at 3°C. The substrate was D-glucose supplemented with yeast extract (0.05 %). Cells of strain ARHSd-9G had morphology of straight or slightly curved elongated rods and demonstrated unusual optical effects under dark-field visible light microscopy. The cells were spore-forming and Gram positive. From the mat sample collected near Lake Zub, the new strain LZ-3 was isolated in pure culture at 3°C. Strain LZ-3 was anaerobic and grew on 0.5 % NaCl mineral medium with Dglucose as a substrate. The gram positive cells were spore-forming. They exhibited a

  16. MRI/TRUS data fusion for prostate brachytherapy. Preliminary results

    CERN Document Server

    Reynier, Christophe; Fourneret, Philippe; Dusserre, André; Gay-Jeune, Cécile; Descotes, Jean-Luc; Bolla, Michel; Giraud, Jean-Yves

    2008-01-01

    Prostate brachytherapy involves implanting radioactive seeds (I125 for instance) permanently in the gland for the treatment of localized prostate cancers, e.g., cT1c-T2a N0 M0 with good prognostic factors. Treatment planning and seed implanting are most often based on the intensive use of transrectal ultrasound (TRUS) imaging. This is not easy because prostate visualization is difficult in this imaging modality particularly as regards the apex of the gland and from an intra- and interobserver variability standpoint. Radioactive seeds are implanted inside open interventional MR machines in some centers. Since MRI was shown to be sensitive and specific for prostate imaging whilst open MR is prohibitive for most centers and makes surgical procedures very complex, this work suggests bringing the MR virtually in the operating room with MRI/TRUS data fusion. This involves providing the physician with bi-modality images (TRUS plus MRI) intended to improve treatment planning from the data registration stage. The pape...

  17. The Sunphotometer Airborne Validation Experiment 2012: Preliminary Results

    Science.gov (United States)

    Estellés, Victor; Marenco, Franco; Ryder, Claire L.; Campanelli, Monica; Expósito, Francisco; Solá, Yolanda; Segura, Sara; Marcos, Carlos; Toledano, Carlos; Berjón, Alberto; Guirado, Carmen; Claxton, Bernard; Todd, Martin

    2013-04-01

    to provide detailed vertically resolved aerosol measurements, in order to compare these to sunphotometer retrievals. Simultaneously, 4 different ground AERONET - Cimel sites were deployed in the Tenerife island, at different latitudes and altitudes for further investigation of spatial and vertical variability. Three of these sites also measured solar radiation components with CM21 pyranometers and CHP1 pirheliometers, for further research on radiative forcing of aerosols. One site was equipped with a Prede POM sun-sky radiometer for comparison with Cimel sunphotometer. On the other hand, for the FENNEC campaign another AERONET Cimel sunphotometer was deployed in Zouerate (Mauritania). The ideal conditions for such a comparison consisted of cloudless skies and high mineral aerosol burdens, brought by the Saharan outflow. Although these conditions were not reached in the Tenerife area during the scheduled field campaign, appropriate conditions were met in western Mauritania, over the AERONET Zouerate site. In this study, we perform a preliminary analysis of the columnar properties of aerosols in the Canary Islands and West Sahara areas during the FENNEC 2011 and FENNEC-SAVEX 2012 field campaigns, with an emphasis on the comparison between the size distributions retrieved from both AERONET and SKYRAD algorithms using the Zouerate Cimel site data. Validation of the vertical integrated aerosol size distributions will be also presented. References - M.Campanelli, V.Estelles, T. Smyth, T. Nakajima, M. Hashimoto, A.Lupi, C. Tomas, "Retrieval of aerosol radiative properties from sun-sky radiometers measurements of ESR network: comparison between the inversion codes Skyrad4.2.pack and the new Skyrad5.pack", European Aerosol Conference, 2011. - V. Estellés, M. Campanelli, M. P. Utrillas, F. Expósito, and J. A. Martínez-Lozano, "Comparison of AERONET and SKYRAD4.2 inversion products retrieved from a Cimel CE318 sunphotometer", Atmos. Meas. Tech. 5, 569—579, 2012.

  18. The Mount Logan (Yukon) Ice Cores: Preliminary Results

    Science.gov (United States)

    Fisher, D. A.

    2004-05-01

    Bourgeois, Mike Demuth, David Fisher, Roy Koerner,Chris Zdanowicz, James Zheng. University of Ottawa: Ian Clarke,Raphaelle Cardyn. National Institute of Polar Research (Japan): Kumiko Goto-Azuma University of New Hampshire: Cam Wake, Kaplan Yalcin. University of Maine: Karl Kreutz, Paul Mayewski, Erich Osterberg. Arctic Institute of North America: Gerald Holdsworth. University of Washington: Eric J. Steig, Summer B. Rupper. University of Copenhagen: Dorthe Dahl-Jensen. David Fisher is the presenter but many contributed to what is a joint preliminary offering.

  19. Follow-up of breast cancer patients: Preliminary findings from nurse-patient consultations and patient surveys

    Directory of Open Access Journals (Sweden)

    Moyez Jiwa

    2009-04-01

    Full Text Available BACKGROUND:Although clinicians in both primary and tertiary care settings are involved in the care of breast cancer patientsfollowing the active treatment phase, few studies report how patients interact with health care providers.METHODS:Participants in this breast cancer follow-up study were recruited from a hospital based nurse-led follow-upclinic in Western Australia. Methods included audio taped, transcribed consultations with Specialist BreastNurses (SBNs and patient self-completed surveys.RESULTS:Preliminary data suggest that SBNs play an important role in supporting women to deal with the impact ofbreast cancer in the years following active treatment. The data suggest that the process of adjustment to adiagnosis of cancer continues for many years after the treatment has ceased. In many cases the women requireon-going support to recalibrate their response to normal physical changes that may or may not be aconsequence of surgery, radiotherapy and chemotherapy.CONCLUSIONS:These preliminary data map the plethora of issues that influence cancer patients in the years followingtreatment. Women who were attending follow-up appointments for breast cancer experienced similar levels ofenablement following SBN consultations as would be expected from consultations with general practitioners.

  20. Hyoid Displacement in Post-Treatment Cancer Patients: Preliminary Findings

    Science.gov (United States)

    Zu, Yihe; Yang, Zhenyu; Perlman, Adrienne L.

    2011-01-01

    Purpose: Dysphagia after head and neck cancer treatment is a health care issue; in some cases, the cause of death is not cancer but, rather, the passage of food or liquid into the lungs. Hyoid displacement is known to be important to safe swallowing function. The purpose of this study was to evaluate hyoid displacement after cancer treatment.…

  1. PRELIMINARY RESULTS OF INTRA CYTOPLASMIC SPERM INJECTION (ICSI) APPLIED ON RABBIT : A TECHNICAL NOTE.

    OpenAIRE

    Escribá, M.J.; García- Ximénez, F.

    1999-01-01

    Abstract not available. Escribá, M.; García- Ximénez, F. (1999). PRELIMINARY RESULTS OF INTRA CYTOPLASMIC SPERM INJECTION (ICSI) APPLIED ON RABBIT : A TECHNICAL NOTE. http://hdl.handle.net/10251/10364.

  2. Uranium-liquid argon calorimetry: preliminary results from the DO tests

    International Nuclear Information System (INIS)

    The motivations for using uranium and liquid argon in sampling calorimetry are reviewed and the pros and cons of the technique are discussed. Preliminary results of the DO uranium-liquid argon test program are presented. 9 refs., 7 figs

  3. 78 FR 34649 - Aluminum Extrusions From the People's Republic of China: Preliminary Results of Countervailing...

    Science.gov (United States)

    2013-06-10

    ...., Ltd Global PMS (Dongguan) Co., Ltd. (Global 12.57 20.75 PMX) Golden Dragon Precise Copper Tube Group..., 76 FR 30653 (May 26, 2011) (Order). \\3\\ See ``Decision Memorandum for Preliminary Results of...

  4. 77 FR 66580 - Certain Preserved Mushrooms From India: Preliminary Results of Antidumping Duty Administrative...

    Science.gov (United States)

    2012-11-06

    ... India, 64 FR 8311 (February 19, 1999) (Mushroom Antidumping Duty Order), remains dispositive... International Trade Administration Certain Preserved Mushrooms From India: Preliminary Results of Antidumping... review of the antidumping duty order on certain preserved mushrooms (mushrooms) from India. The period...

  5. Event-Based Control over Networks: Some Research Questions and Preliminary Results

    OpenAIRE

    Henningsson, Toivo; Cervin, Anton

    2006-01-01

    The paper discusses some research questions related to event-based control over networks and presents preliminary results regarding event-based minimum-variance control of first-order systems with specified minimum inter-event times.

  6. Plasma technology for treating hazardous, radioactive, and mixed waste: Critical technology issues and preliminary results

    International Nuclear Information System (INIS)

    Plasma processing technology is currently being considered for the treatment of hazardous, radioactive, and mixed waste. The paper reviews the technology and proposes critical issues to be addressed in applying plasma to waste treatment. Preliminary results from a small scale plasma arcjet experiment with acetone were compared with predictions from ASPEN, a chemical equilibrium code. Preliminary results indicate that proper mixing and models describing the high temperature plasma chemical kinetics are needed to adequately predict the composition of the offgases

  7. Fungi in coastal tableland soils of northeastern Brazil : Preliminary results

    NARCIS (Netherlands)

    Araujo, QR; Bezerra, JL; Faleiro, RG; Bezerra, KMT; Menezes, PV; Faleiro, ASG; Ogram, AV; Al-Agely, A; Comerford, NB

    2004-01-01

    Soil compaction causes reduced agricultural production due to limited root development resulting in reduced water and nutrient access. This is particularly true of soils of the Brazilian tablelands (similar to200000 km(2)) that are characterized by a naturally occurring compact subsoil horizon. Most

  8. Preliminary results of standard quantitative analysis by ED-XRF

    Energy Technology Data Exchange (ETDEWEB)

    Lara, Alessandro L. de; Franca, Alana C.; Neto, Manoel R.M.; Paschuk, Sergei A., E-mail: alellara@hotmail.com [Universidade Tecnologica Federal do Parana (UTFPR), Curitiba, PR (Brazil). Dept. de Fisica; Denyak, Valeriy, E-mail: denyak@gmail.com [Instituto de Pesquisa Pele Pequeno Principe (IPPP), Curitiba, PR (Brazil)

    2013-07-01

    A comparison between the results of elemental concentration proposed by XRS-FP software , using data obtained by EDXRF technique with those obtained by stoichiometric calculation was performed. For this purpose, five standard samples of known compounds were produced: two lead- oxide, magnesium chloride and iodine in controlled amounts. The compounds were subsequently mixed and compressed to form tablets. The samples were irradiated in three endpoints, according to an orientation. The measurements were performed at the Laboratory for Radiological UTFPR using X-123SDD the Amptek detector and X-ray tube with silver target from the same manufacturer. The operating conditions tube were 05μA current to a 40 kV voltage. Finally, the 15 spectra analyzed with the software to determine the concentration of chlorine, iodine and lead. Data from this analysis were compared with results expected in stoichiometric calculations. The data provided by the program, a convergence of results, indicating homogeneity of the samples was found. Compared to the stoichiometric calculation, a considerable discrepancy that may be the result of a misconfiguration or contamination of the sample was found. At the end, we created a proposal for continuation of the work using an auxiliary calculation should be developed in the next step.

  9. Preliminary results of in vitro propagation of Guayule

    Science.gov (United States)

    Dastoor, M. N.; Schubert, W. W.; Petersen, G. R.

    1981-01-01

    Guayule, Parthenium argentatum Gray, was first established in tissue culture by Bonner and Arreguin (1950) as a means to study the effects of various chemicals and extracts on rubber production. The propagation of whole guayule plants from tissue culture, however, has not been accomplished. The reported investigation is concerned with such an objective. In an attempt to stimulate rubber production in Guayule, Yokoyama et al. (1977) sprayed juvenile plants with 2-(3,4-dichloro-phenoxy)triethylamine (TEA derivative). This treatment resulted in increased isoprenoid levels in the plant tissue. In the current investigation, experiments were conducted to study the effect of TEA derivative on in vitro cultures. It was found that a suppression of callus formation occurs at a 10 mg/L concentration of TEA derivative with a resultant increase of shoot formation. Lower and higher concentrations of TEA derivative promote callus formation.

  10. Are saponins and sapogenins precursors of prednisolone? Preliminary results

    Directory of Open Access Journals (Sweden)

    Giuseppe Federico Labella

    2015-11-01

    Full Text Available The transformation of cortisol into prednisolone in cattle faeces was demonstrated and provided by literature, given the structural similarity of prednisolone with cortisol. In this study, we evaluated a possible neo-formation of prednisolone, as results of a faecal or environmental contamination. A saponine, α-solanine, and a sapogenin, diosgenin, were selected as possible precursors. A simple method without extraction was applied. The analyses were performed by HPLC–MSn to evaluate the possible transformations. The results showed that prednisolone was detected in the faecal suspension spiked with diosgenin at t= 8h, while cortisol was also detected at t = 24h in the sample of faeces spiked with α-solanine. In the feed and in the control samples, no transformations were observed.

  11. Preliminary results on Alfven wave system in the TCABR tokamak

    International Nuclear Information System (INIS)

    A brief review of the Alfven Wave Excitation System (AWES) designed for the TCABR tokamak and the first experimental results on RF plasma heating are presented. One of four antenna modules has been completely installed in the vacuum chamber and the initial experiments were carried out in the low power regime using the four-phase RF generator. The main objectives were the antenna tuning according to the typical plasma parameters of TCABR and the evaluation of the antenna parasitic loading, as well as the calibration of the RF diagnostic tools in real discharge conditions. The first results have been obtained with standard diagnostics and with the RF signals measured using high sampling rate digital oscilloscopes. They showed that daily antenna cleaning and correct wave helicity excitation reduce significantly the parasitic loading and are crucial for efficient plasma coupling

  12. Processed Vietnamese ginseng: Preliminary results in chemistry and biological activity

    OpenAIRE

    Le, Thi Hong Van; Lee, Seo Young; Kim, Tae Ryong; Kim, Jae Young; Kwon, Sung Won; NGUYEN, NGOC KHOI; Park, Jeong Hill; Nguyen, Minh Duc

    2013-01-01

    Background This study was carried out to investigate the effect of the steaming process on chemical constituents, free radical scavenging activity, and antiproliferative effect of Vietnamese ginseng. Methods Samples of powdered Vietnamese ginseng were steamed at 120°C for various times and their extracts were subjected to chemical and biological studies. Results Upon steaming, contents of polar ginsenosides, such as Rb1, Rc, Rd, Re, and Rg1, were rapidly decreased, whereas less polar ginsenos...

  13. Impediments to Marketing African Natural products From Ghana: Preliminary Results

    OpenAIRE

    Govindasamy, Ramu; Onyango, Benjamin M.; Puduri, Venkata S.; Simon, James E.; Asante-Dartey, Juliana; Arthur, Hanson; Diawuo, Bismarck; Acquaye, Dan

    2006-01-01

    For most of the African countries agriculture still remains the mainstay of the economies supplying both food and incomes via marketable surpluses. However, many odds against agriculture such low productivity, poor prices, and drought among others make it unsustainable. Results thus far show that such dependence has contributed little to neither economic development nor growth. Still many of its people living on and from agriculture remain poor, and are susceptible to hunger and malnutrition....

  14. ATOM PROBE STUDY OF TITANIUM BASE ALLOYS : PRELIMINARY RESULTS

    OpenAIRE

    Menand, A.; Chambreland, S.; Martin, C

    1986-01-01

    Two different titanium base alloys, Ti46 Al54 and Ti88.8 Cu2.3, Al8.9, have been studied by atom probe microanalysis. A precipitate of Ti2 Al was analysed in the binary alloys. Micro-analysis of Ti Cu Al alloy revealed the presence of Copper enriched zones. The study has also exhibited a penetration of Hydrogen in the samples, probably due to preparation technique. The results demonstrate the feasibility of studies on titanium base alloys by mean of atom probe.

  15. Preliminary results of ITEC over an equatorial station

    International Nuclear Information System (INIS)

    Total electron content (TEC) was obtained from bottomside ionograms recorded at an equatorial station (Ouagadougou, 12.4 deg. N, 358.5 deg. E). Variability in TEC obtained in this way (ITEC) was investigated. Diurnal, seasonal and solar cycle effects were observed. Both absolute and relative variability were considered. The results obtained were compared with those of another equatorial station (Ghana, 5.63 deg. N, 359.8 deg. E) where the TEC was obtained by the Faraday rotation technique. The variations in variability at both stations follow the same trend. (author)

  16. Preliminary results from a shallow water benthic grazing study

    Science.gov (United States)

    Jones, N.L.; Monismith, Stephen G.; Thompson, Janet K.

    2005-01-01

    The nutrient-rich, shallow waters of San Francisco Bay support high rates of primary production, limited not by nutrients but by light availability and benthic grazing (Alpine and others 1992; Cloern 1982). Phytoplankton blooms are an important food source for upper trophic levels. Consequently animal populations, such as fish, may suffer under conditions of high benthic bivalve grazing. It has been hypothesized that several species of fish are suffering as a result of severe decreases in available phytoplankton since the introduction of Potamocorbula amurensis into San Francisco Bay (Feyrer 2003).

  17. Development and preliminary results of radio frequency ion source

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Yahong, E-mail: xieyh@ipp.ac.cn; Hu, Chundong; Jiang, Caichao; Chen, Yuqian; Gu, Yumin; Su, Renxue; Xie, Yuanlai; Liu, Zhimin [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China)

    2016-02-15

    A radio frequency (RF) ion source was designed and developed for neutral beam injector. A RF driver test bed was used with a RF generator with maximum power of 25 kW with 1 MHz frequency and a matching box. In order to study the characteristic of RF plasma generation, the capacitance in the matching box was adjusted with different cases. The results show that lower capacitance will better the stability of the plasma with higher RF power. In the future, new RF coils and matching box will be developed for plasma generators with higher RF power of 50 kW.

  18. Simulation of diurnal thermal energy storage systems: Preliminary results

    Science.gov (United States)

    Katipamula, S.; Somasundaram, S.; Williams, H. R.

    1994-12-01

    This report describes the results of a simulation of thermal energy storage (TES) integrated with a simple-cycle gas turbine cogeneration system. Integrating TES with cogeneration can serve the electrical and thermal loads independently while firing all fuel in the gas turbine. The detailed engineering and economic feasibility of diurnal TES systems integrated with cogeneration systems has been described in two previous PNL reports. The objective of this study was to lay the ground work for optimization of the TES system designs using a simulation tool called TRNSYS (TRaNsient SYstem Simulation). TRNSYS is a transient simulation program with a sequential-modular structure developed at the Solar Energy Laboratory, University of Wisconsin-Madison. The two TES systems selected for the base-case simulations were: (1) a one-tank storage model to represent the oil/rock TES system; and (2) a two-tank storage model to represent the molten nitrate salt TES system. Results of the study clearly indicate that an engineering optimization of the TES system using TRNSYS is possible. The one-tank stratified oil/rock storage model described here is a good starting point for parametric studies of a TES system. Further developments to the TRNSYS library of available models (economizer, evaporator, gas turbine, etc.) are recommended so that the phase-change processes is accurately treated.

  19. Simulation of diurnal thermal energy storage systems: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Katipamula, S.; Somasundaram, S. [Pacific Northwest Lab., Richland, WA (United States); Williams, H.R. [Univ. of Alaska, Fairbanks, AK (United States). Dept. of Mechanical Engineering

    1994-12-01

    This report describes the results of a simulation of thermal energy storage (TES) integrated with a simple-cycle gas turbine cogeneration system. Integrating TES with cogeneration can serve the electrical and thermal loads independently while firing all fuel in the gas turbine. The detailed engineering and economic feasibility of diurnal TES systems integrated with cogeneration systems has been described in two previous PNL reports. The objective of this study was to lay the ground work for optimization of the TES system designs using a simulation tool called TRNSYS (TRaNsient SYstem Simulation). TRNSYS is a transient simulation program with a sequential-modular structure developed at the Solar Energy Laboratory, University of Wisconsin-Madison. The two TES systems selected for the base-case simulations were: (1) a one-tank storage model to represent the oil/rock TES system, and (2) a two-tank storage model to represent the molten nitrate salt TES system. Results of the study clearly indicate that an engineering optimization of the TES system using TRNSYS is possible. The one-tank stratified oil/rock storage model described here is a good starting point for parametric studies of a TES system. Further developments to the TRNSYS library of available models (economizer, evaporator, gas turbine, etc.) are recommended so that the phase-change processes is accurately treated.

  20. Ramadan fasting: Evidence or expert opinion? Results of preliminary studies

    Directory of Open Access Journals (Sweden)

    1Maryam Kazemi

    2013-11-01

    Full Text Available Each year, over a billion Muslims fast worldwide during the month of Ramadan. Through this religious practice, not only will one have spiritual growth, but can improve his/her diet, which is of pivotal importance in this month. Conversely, the available evidence regarding the health benefits of Ramadan fasting is scarce and highly contentious. Although Islam exempts patients from fasting, many of them fast conceivably and their clinical condition is prone to deteriorate. This is due to the persistent gap between current expert knowledge and conclusive, strong evidence regarding the pathophysiologic and metabolic alterations by fasting, and the consensus that healthcare professionals should reach, in order to manage various patient groups during this month. In this review, we summarize the results of our initial studies regarding the effects of Ramadan fasting on some clinical conditions including alterations of body composition. We also go through the important clinical results of patients who have had previous history of cardiovascular disease, type 2 diabetes, asthma and renal colic. Our studies have presented some evidence in favor of Ramadan fasting and encourage those with mentioned diseases to consult their physicians and follow medical and scientific recommendations. We attempt to present some relevant evidence clarify future scopes in this area of study, and provide suggestions for future investigations.

  1. Preliminary Results From a Newly Established Behavioral Health Home

    Directory of Open Access Journals (Sweden)

    Alexandros Maragakis

    2015-05-01

    Full Text Available Objective: Individuals with serious mental illness (SMI have higher rates of preventable diseases such as diabetes in comparison to the general population. While multifaceted, these high rates of preventable diseases in the population with SMI may be partially attributed to limited access to primary care. A new program, the Behavioral Health Home (BHH, which allows for the delivery of somatic care coordination and population-based care, may provide this population with the much needed somatic coordination and education it requires. Methods: The impact of the population-based health management program of the BHH identification and severity rating of glucose metabolism disorders was assessed during the initial 10 months of the BHH. Results: Multiple patients were identified who either were not having hemoglobin A1c (HbA1c levels drawn per recommended guidelines for individuals prescribed antipsychotic medications or were within diabetic range but did not have a diagnosis of diabetes. Mixed results occurred in regard to patients’ HbA1c levels while engaging in the BHH. Conclusion: This case study provides some initial evidence for the utility of the BHH in regard to identifying patients who need preventive care.

  2. Ramadan fasting: Evidence or expert opinion? Results of preliminary studies

    Directory of Open Access Journals (Sweden)

    Maryam Kazemi

    2013-12-01

    Full Text Available Each year, over a billion Muslims fast worldwide during the month of Ramadan.  Through this religious practice, not only will one have spiritual growth, but can improve his/her diet, which is of pivotal importance in this month. Conversely, the available evidence regarding the health benefits of Ramadan fasting is scarce and highly contentious. Although Islam exempts patients from fasting, many of them fast conceivably and their clinical condition is prone to deteriorate. This is due to the persistent gap between current expert knowledge and conclusive, strong evidence regarding the pathophysiologic and metabolic alterations by fasting, and the consensus that healthcare professionals should reach, in order to manage various patient groups during this month. In this review, we summarize the results of our initial studies regarding the effects of Ramadan fasting on some clinical conditions including alterations of body composition. We also go through the important clinical results of patients who have had previous history of cardiovascular disease, type 2 diabetes, asthma and renal colic. Our studies have presented some evidence in favor of Ramadan fasting and encourage those with mentioned diseases to consult their physicians and follow medical and scientific recommendations. We attempt to present some relevant evidence clarify future scopes in this area of study, and provide suggestions for future investigations.

  3. Speckle imaging with the MAMA detector: Preliminary results

    Science.gov (United States)

    Horch, E.; Heanue, J. F.; Morgan, J. S.; Timothy, J. G.

    1994-01-01

    We report on the first successful speckle imaging studies using the Stanford University speckle interferometry system, an instrument that uses a multianode microchannel array (MAMA) detector as the imaging device. The method of producing high-resolution images is based on the analysis of so-called 'near-axis' bispectral subplanes and follows the work of Lohmann et al. (1983). In order to improve the signal-to-noise ratio in the bispectrum, the frame-oversampling technique of Nakajima et al. (1989) is also employed. We present speckle imaging results of binary stars and other objects from V magnitude 5.5 to 11, and the quality of these images is studied. While the Stanford system is capable of good speckle imaging results, it is limited by the overall quantum efficiency of the current MAMA detector (which is due to the response of the photocathode at visible wavelengths and other detector properties) and by channel saturation of the microchannel plate. Both affect the signal-to-noise ratio of the power spectrum and bispectrum.

  4. Simulating lightning into the RAMS model: implementation and preliminary results

    Directory of Open Access Journals (Sweden)

    S. Federico

    2014-05-01

    Full Text Available This paper shows the results of a tailored version of a previously published methodology, designed to simulate lightning activity, implemented into the Regional Atmospheric Modeling System (RAMS. The method gives the flash density at the resolution of the RAMS grid-scale allowing for a detailed analysis of the evolution of simulated lightning activity. The system is applied in detail to two case studies occurred over the Lazio Region, in Central Italy. Simulations are compared with the lightning activity detected by the LINET network. The cases refer to two thunderstorms of different intensity. Results show that the model predicts reasonably well both cases and that the lightning activity is well reproduced especially for the most intense case. However, there are errors in timing and positioning of the convection, whose magnitude depends on the case study, which mirrors in timing and positioning errors of the lightning distribution. To assess objectively the performance of the methodology, standard scores are presented for four additional case studies. Scores show the ability of the methodology to simulate the daily lightning activity for different spatial scales and for two different minimum thresholds of flash number density. The performance decreases at finer spatial scales and for higher thresholds. The comparison of simulated and observed lighting activity is an immediate and powerful tool to assess the model ability to reproduce the intensity and the evolution of the convection. This shows the importance of the use of computationally efficient lightning schemes, such as the one described in this paper, in forecast models.

  5. Radiation pasteurization of poultry feed: Preliminary results of feeding tests

    International Nuclear Information System (INIS)

    Feed used to rear farm animals for human consumption has often been implicated as a vehicle for dissemination of microbial pathogens that can adversely affect both animals or birds, and humans. Radiation pasteurization of animal feed to improve its microbiological quality should reduce the incidence of feed-borne infection in the herd or flock. This would result in safer food for the consumer, and improved economic performance of the production unit. This latter benefit is particularly important because it would directly offset the cost of treating the feed. The likelihood of occurrence, as well as the magnitude, of any improved economic performance in the herd or flock consuming the irradiated feed must be determined experimentally. Accordingly, short term feeding tests were carried out to determine the effect of radiation pasteurization of poultry feed on growth performance of young chicks. The results suggest that radiation pasteurization of poultry feed may have a beneficial effect on the feed conversion efficiency of the birds consuming that feed. 10 refs, 8 tabs

  6. Preliminary Hydrogeologic Characterization Results from the Wallula Basalt Pilot Study

    Energy Technology Data Exchange (ETDEWEB)

    B.P. McGrail; E. C. Sullivan; F. A. Spane; D. H. Bacon; G. Hund; P. D. Thorne; C. J. Thompson; S. P. Reidel; F. S. Colwell

    2009-12-01

    The DOE's Big Sky Regional Carbon Sequestration Partnership has completed drilling the first continental flood basalt sequestration pilot borehole to a total depth (TD) of 4,110 feet on the Boise White Paper Mill property at Wallula, Washington. Site suitability was assessed prior to drilling by the 2007-2008 acquisition, processing and analysis of a four-mile, five-line three component seismic swath, which was processed as a single data-dense line. Analysis of the seismic survey data indicated a composite basalt formation thickness of {approx}8,000 feet and absence of major geologic structures (i.e., faults) along the line imaged by the seismic swath. Drilling of Wallula pilot borehole was initiated on January 13, 2009 and reached TD on April 6, 2009. Based on characterization results obtained during drilling, three basalt breccia zones were identified between the depth interval of 2,716 and 2,910 feet, as being suitable injection reservoir for a subsequent CO2 injection pilot study. The targeted injection reservoir lies stratigraphically below the massive Umtanum Member of the Grande Ronde Basalt, whose flow-interior section possesses regionally recognized low-permeability characteristics. The identified composite injection zone reservoir provides a unique and attractive opportunity to scientifically study the reservoir behavior of three inter-connected reservoir intervals below primary and secondary caprock confining zones. Drill cuttings, wireline geophysical logs, and 31one-inch diameter rotary sidewall cores provided geologic data for characterization of rock properties. XRF analyses of selected rock samples provided geochemical characterizations of the rocks and stratigraphic control for the basalt flows encountered by the Wallula pilot borehole. Based on the geochemical results, the pilot borehole was terminated in the Wapshilla Ridge 1 flow of the Grande Ronde Basalt Formation. Detailed hydrologic test characterizations of 12 basalt interflow

  7. Preliminary results of direct cell-matrix assembly technology

    Institute of Scientific and Technical Information of China (English)

    LIU Haixia; YAN Yongnian; XIONG Zhuo; CHENG Jie; WANG Xiaohong; LIN Feng; WANG Changyong

    2005-01-01

    @@ Tissue loss and end-stage organ failure has been an emergent problem for humanity[1]. Solving this problem at the most basic level is currently an area of great interest to many researchers. At the end of the 20th century, tissue engineering technology began using formed scaffolds to indirectly control the assembly of cells. This technology has resulted in a new way to artificially fabricate tissues. But the method has been limited to simple tissue types, such as bone, skin, muscle and tendon[2―5]. The fabrication of complex organs by this technology is still not possible. A possible alternative is assembling cells directly into a viable and predefined structure[6―9].

  8. Gastrointestinal transfer of neptunium (V) in newborn baboons: preliminary results

    International Nuclear Information System (INIS)

    To measure gastrointestinal neptunium absorption, baboons aged from 17 hours to 26 days were gavaged with an oral dose of 0.002 ug/kg of neptunium-239 nitrate. Absorption ranged from 3.71 to 0.113 per cent of the gavaged dose which was, 88 to 3 times higher than the values for adults. This range was reduced to 41 to 3 when doubtful results were discarded because of possible lung contamination. Absorption was expressed in terms of retention per animal at killing since collection of urine and faeces from neonates was not possible. For the same animals the skeleton/liver ratio of the neptunium burden rose continuously in the 26 dav-old baboon and reached twice the mean adult value

  9. Preliminary results on Macroalgae distribution in destructive processes

    Directory of Open Access Journals (Sweden)

    O.I. OSKOLSKAYA

    2012-12-01

    Full Text Available It has been shown, that the destruction of the coastal strip in region of action of Mikhailovsky landslide results in change of species structure and dominant species photophilous Cystoseira barbara on sciophylous Gracilaria verrucosa. In accordance with increasing sediments amount in sea water biomass and the morpho-functional parameters of the photophilous species are reducing, and at the sciophylous are growing. Progressing phenomenon of epiphytism is observed in algal populations in the southern part of researched region which is possible to consider as response reaction, leads to increase a synthesizing surface. Decreasing physiological activity is compensated by growth of the total surface of macrophytes. The increase of a sea water sediments leads to lowering ratio of long and shortwave pigments level of ATP-ase activity and raising concentration of the total sum of pigments in thalli.

  10. Bioenergy potentials from forestry to 2050. Preliminary results

    International Nuclear Information System (INIS)

    In this study a bottom-up scenario analysis of the global bioenergy production potential is carried out, with specific attention for the impact of underlying factors, existing outlook studies on demand and supply and gaps in the knowledge base that explain the large range in estimates. Key variables are the demand for industrial roundwood and fuelwood, plantation establishment rates and natural forest growth. Key uncertainties are the supply of wood from trees outside and the impact of sustainable forest management (SFM) of yields. Results show that the world is capable of meeting the future demand for industrial roundwood and fuelwood, without further deforestation. The total potential of bioenergy from surplus forest growth and residues is estimated at 27 to 140 EJy-1 in 2050

  11. Preliminary Results of Testing of Flow Effects on Evaporator Scaling

    Energy Technology Data Exchange (ETDEWEB)

    Hu, M.Z.

    2002-02-15

    This investigation has focused on the effects of fluid flow on solids deposition from solutions that simulate the feed to the 2H evaporator at the Savannah River Site. Literature studies indicate that the fluid flow (or shear) affects particle-particle and particle-surface interactions and thus the phenomena of particle aggregation in solution and particle deposition (i.e., scale formation) onto solid surfaces. Experimental tests were conducted with two configurations: (1) using a rheometer to provide controlled shear conditions and (2) using controlled flow of reactive solution through samples of stainless steel tubing. All tests were conducted at 80 C and at high silicon and aluminum concentrations, 0.133 M each, in solutions containing 4 M sodium hydroxide and 1 A4 each of sodium nitrate and sodium nitrite. Two findings from these experiments are important for consideration in developing approaches for reducing or eliminating evaporator scaling problems: (1) The rheometer tests suggested that for the conditions studied, maximum solids deposition occurs at a moderate shear rate, approximately 12 s{sup -1}. That value is expected to be on the order of shear rates that will occur in various parts of the evaporator system; for instance, a 6 gal/min single-phase liquid flow through the 2-in. lift or gravity drain lines would result in a shear rate of approximately 16 s{sup -1}. These results imply that engineering approaches aimed at reducing deposits through increased mixing would need to generate shear near all surfaces significantly greater than 12 s{sup -1}. However, further testing is needed to set a target value for shear that is applicable to evaporator operation. This is because the measured trend is not statistically significant at the 95% confidence interval due to variability in the results. In addition, testing at higher temperatures and lower concentrations of aluminum and silicon would more accurately represent conditions in the evaporator. Without

  12. Preliminary results from the MAMA detectors for the SOHO mission

    Science.gov (United States)

    Slater, David C.; Bergamini, Paolo; Bumala, Robert W.; Timothy, J. G.

    1993-01-01

    Multi-Anode Microchannel Array (MAMA) detector systems are being fabricated and tested for use in the Solar Ultraviolet Measurements of Emitted Radiation (SUMER) and the Ultraviolet Coronagraph Spectrometer (UVCS) instruments on the ESA/NASA Solar and Heliospheric Observatory (SOHO) mission. The SOHO MAMA detector systems have formats of 360 x 1024 pixels and pixel dimensions of 25 x 25 sq microns and are optimized for operation at Extreme Ultraviolet (EUV) wavelengths between 40 and 160 nm. In this paper we report on the initial results of measurements of the performance characteristics of the first flight-configuration detector system employing the new custom Application Specific Integrated Circuits (ASICs) which are designed to improve both the dynamic range and the uniformity of response. The performance characteristics of this detector system are compared with those of earlier breadboard systems employing discrete-component electronics circuits.

  13. SOME PRELIMINARY RESULTS FROM STUDY OF CRUSTAL DEFORMATION IN VIETNAM

    Institute of Scientific and Technical Information of China (English)

    Cao Dinh Trieu; Le Van Dung; Nguyen Huu Tuyen; Pham Nam Hung

    2003-01-01

    In this work, the authors present some results of strain monitoring within the territory of Vietnam from 1984 to 2001. Data analysis shows that (1) the Phu Lien area is tectonically stable with low strain rate, 1×10-6/a; (2) the Hoa Binh area has indication of tectonic instability with relatively high strain rate of the earth crust: absolute value of the strain reaching 100 × 10-6 , usual average strain amplitude of 60 × 10-6 , whereas the monthly average strain intensity varies in a range from 30× 10-6 to 50× 10-6 (3) there are clear indications of the strain state of the earth crust before occurrence of earthquakes of medium or higher magnitude. This is a very important indication in the research and short-term prediction of earthquakes, especially for the areas with low seismic stability like the NW of Vietnam.

  14. Immersive virtual environments for emotional engineering: description and preliminary results.

    Science.gov (United States)

    Rodríguez, Alejandro; Rey, Beatriz; Alcañiz, Mariano

    2011-01-01

    This work aims to identify the arousal and presence level during an emotional engineering study. During the experimental sessions, a high-immersion Virtual Reality (VR) system, a CAVE-like configuration, will be used. Thirty-six volunteers will navigate through virtual houses that can be customized and that have been designed for emotional induction. Emotional induction will be obtained by stimulating the senses of sight, hearing and smell. For this purpose, the ambient lighting, music and smell will be controlled by the researcher, who will create a comfortable environment for the subject. Several physiological variables - Electrocardiogram (ECG), Respiratory signal and Galvanic Skin Response (GSR) - will be recorded during the sessions. The obtained results will help furniture companies identify the senses that have more influence on emotions and will be the basis for new studies about user needs in the sector of furniture and interior decoration.

  15. Pharyngeal airway changes after bimaxillary orthognathic surgery - preliminary results

    Directory of Open Access Journals (Sweden)

    Stefanović Neda Lj.

    2015-01-01

    Full Text Available Introduction. Dentofacial deformity, a deviation from normal facial proportions and dental relationships, is corrected by jaw repositioning in all three spatial planes, which changes the position and tension of the surrounding tissues, bones and muscles. These changes may also affect the dimensions of the pharyngeal airways (PA. Objective. The aim of this study was to evaluate and compare three-dimensional PA changes in patients treated by a combination mandibular set-back/maxillary advancement versus patients that had bimaxillary advancement with genioplasty. Methods. The sample consisted of 7 patients treated by combined mandibular set-back/maxillary advancement and 7 patients treated with bimaxillary advancement surgery. Nasopharyngeal (NP volume, oropharyngeal (OP volume and the area of maximum constriction (AMC in the OP were measured on CBCT scans (2 mA/120 kV/12’’ FOV taken before (T1 and 3 months after surgery (T2. Paired samples t-test was used for analyzing statistical significance of changes (p≤0.05. Results. OP volume and AMC increase after bimaxillary advancement was statistically significant, while for the mandibular set-back group the increase was non-significant. NP volume was not reduced in any of the two groups. No significant differences in PA dimensions were found between groups at neither T1 nor T2 time points. Conclusion. Results suggest that the combination of mandibular set-back/maxillary advancement did not reduce airway dimensions, while bimaxillary advancement surgery led to a statistically significant increase in the OP dimensions.

  16. Electromagnetic-Tracked Biopsy under Ultrasound Guidance: Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Hakime, Antoine, E-mail: thakime@yahoo.com; Deschamps, Frederic; Marques De Carvalho, Enio Garcia; Barah, Ali; Auperin, Anne; Baere, Thierry De [Gustave Roussy Institute (France)

    2012-08-15

    Purpose: This study was designed to evaluate the accuracy and safety of electromagnetic needle tracking for sonographically guided percutaneous liver biopsies. Methods: We performed 23 consecutive ultrasound-guided liver biopsies for liver nodules with an electromagnetic tracking of the needle. A sensor placed at the tip of a sterile stylet (18G) inserted in a coaxial guiding trocar (16G) used for biopsy was localized in real time relative to the ultrasound imaging plane, thanks to an electromagnetic transmitter and two sensors on the ultrasound probe. This allows for electronic display of the needle tip location and the future needle path overlaid on the real-time ultrasound image. Distance between needle tip position and its electronic display, number of needle punctures, number of needle pull backs for redirection, technical success (needle positioned in the target), diagnostic success (correct histopathology result), procedure time, and complication were evaluated according to lesion sizes, depth and location, operator experience, and 'in-plane' or 'out-of-plane' needle approach. Results: Electronic display was always within 2 mm from the real position of the needle tip. The technical success rate was 100%. A single needle puncture without repuncture was used in all patients. Pull backs were necessary in six patients (26%) to obtain correct needle placement. The overall diagnostic success rate was 91%. The overall true-positive, true-negative, false-negative, and failure rates of the biopsy were 100% (19/19) 100% (2/2), 0% (0/23), and 9% (2/23). The median total procedure time from the skin puncture to the needle in the target was 30 sec (from 5-60 s). Lesion depth and localizations, operator experience, in-plane or out-of-plane approach did not affect significantly the technical, diagnostic success, or procedure time. Even when the tumor size decreased, the procedure time did not increase. Conclusions: Electromagnetic-tracked biopsy is

  17. The ABC Schizophrenia Study: a preliminary overview of the results.

    Science.gov (United States)

    Häfner, H; Maurer, K; Löffler, W; an der Heiden, W; Munk-Jørgensen, P; Hambrecht, M; Riecher-Rössler, A

    1998-08-01

    The ABC Schizophrenia Study, a large-scale epidemiological and neurobiological research project commenced in 1987, initially pursued two aims: (1) to elucidate the possible causes of the sex difference in age at first admission for schizophrenia and (2) to analyse the early course of the disorder from onset until first contact and its implications for further course and outcome. First, transnational case-register data (for Denmark and Germany) were compared, second, a population-based sample of first-episode cases of schizophrenia (n = 232) were selected and third, the results obtained were compared with data from the WHO Determinants of Outcome Study by using a systematic methodology. A consistent result was a 3-4 years higher age of onset for women by any definition of onset, which was not explainable by social variables, such as differences in the male-female societal roles. A sensitivity-reducing effect of oestrogen on central D2 receptors was identified as the underlying neurobiological mechanism in animal experiments. Applicability to humans with schizophrenia was established in a controlled clinical study. A comparison of familial and sporadic cases showed that in cases with a high genetic load, the sex difference in age of onset disappeared due to a clearly reduced age of onset in women, whereas in sporadic cases it increased. To analyse early course retrospectively, a semistructured interview, IRAOS, was developed. The early stages of the disorder were reconstructed in comparison with age- and sex-matched controls from the same population of origin. The initial signs consisted mainly of negative and affective symptoms, which accumulated exponentially until the first episode, as did the later emerging positive symptoms. Social disability appeared 2-4 years before first admission on average. In early-onset cases, social course and outcome, studied prospectively over 5 years, was determined by the level of social development at onset through social stagnation

  18. Relationship Between Dual Time Point FDG PET and Immunohistochemical Parameters in Preoperative Colorectal Cancer: Preliminary Study

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jai Hyuen; Lee, Won Ae; Park, Seok Gun; Park, Dong Kook; Namgung, Hwan [Dankook Univ. College of Medicine, Cheonan (Korea, Republic of)

    2012-03-15

    The clinical availability of 2 deoxy 2 [18F] fluoro D glucose (FDG) dual time point positron emission tomography/computerized tomography (DTPP) has been investigated in diverse oncologic fields. The aim of this preliminary study was to evaluate the relationship between various immunohistopathologic markers reflecting disease progression of colorectal cancer and parameters extracted from FDG DTPP in colorectal cancer patients. Forty seven patients with histologically confirmed colorectal cancer were analyzed in this preliminary study. FDG DTPP consisted of an early scan 1 h after FDG injection and a delayed scan 1.5 h after the early scan. Based on an analysis of FDG DTPP, we estimated the maximum standardized uptake value (SUV) of tumors on the early and delayed scans (SUV{sup earlya}nd SUV{sup delayed,} respectively). The retention index (RI) was calculated as follows: (SUV{sup delayed-} SUV{sup early)} x 100/ SUV{sup early.} The clinicopathological findings (size and T and N stages) and immunohistochemical factors [glucose transporter 1 (GLUT 1), hexokinase 2 (HK 2), p53, P504S, and {beta} catenin] were analyzed by visual analysis. The RIs calculated from the SUVs ranged from -1.8 to 73.4 (31.8{+-}15.5). The RIs were significantly higher in patients with high T stages (T3 and T4) than with low T stages (T1 and T2; P<0.05). Among the immunohistochemical analytic markers, GLUT 1 had the highest positive staining rate (93.6%) compared to other markers. Based on unvariable analysis, it was shown that the RI of high level GLUT 1 expression was significantly higher than low level GLUT 1 expression (p=0.01), and the RI of high level p53 expression (p=0.08). Multivariate analysis to investigate a link between RI and clinico pathologic parameters of colorectal carcinoma showed that GLUT 1, p53, and T staging were independently connected with increased RIs (p<0.05, total) using backward selection methods. There was no significant statistical relationship between SUV

  19. Untreatable Pain Resulting from Abdominal Cancer: New Hope from Biophysics?

    Directory of Open Access Journals (Sweden)

    Marineo G

    2003-01-01

    Full Text Available CONTEXT: Visceral pain characterizing pancreatic cancer is the most difficult symptom of the disease to control and can significantly impair the quality of life which remains and increase the demand for euthanasia. AIM: To investigate a possible new method based on biophysical principles (scrambler therapy to be used in the effective treatment of drug-resistant oncological pain of the visceral/neuropathic type. SETTING: Eleven terminal cancer patients (3 pancreas, 4 colon, 4 gastric suffering from elevated drug resistant visceral pain. DESIGN: The trial program was related to the first ten treatment sessions. Subsequently, each patient continued to receive treatment until death. MAIN OUTCOME MEASURES: Pain measures were performed using the visual analogue scale before and after each treatment session and accompanied by diary recordings of the duration of analgesia in the hours following each single application. Any variation in pain-killing drug consumption was also recorded. RESULTS: All patients reacted positively to the treatment throughout the whole reference period. Pain intensity showed a significant decrease (P less than 0.001, accompanied by a gradual rise both in the pain threshold and the duration of analgesia. Nine (81.8% of the patients suspended pain-killers within the first 5 applications, while the remaining two (18.2% considerably reduced the dosage taken prior to scrambler therapy. No undesirable side effects were observed. Compliance was found to be optimal. CONCLUSIONS: The preliminary results obtained using scrambler therapy are extremely encouraging, both in terms of enhanced pain control after each treatment session and in view of the possible maintenance of effectiveness over time.

  20. Preliminary results on isotopic methods for the control of wines

    International Nuclear Information System (INIS)

    Full text: Isotopic methods have shown to be a major tool for checking the compliance of food products and beverages with national and international regulations. This paper presents some results on isotopic methods for control of wines. We developed a method for determining 13C/12C and 18O/16O isotope ratios in wine's ethanol and water. These ratios are significantly influenced by geo-climatic conditions of the origin region of wine, the type of plant (species or subspecies), and the year of harvest. The determination of 13C/12C ratio of wine ethanol was performed in three steps: (I) 500 ml of a wine sample was distilled at constant reflux ratio, (10). The distillate was collected with an ethanol content of about 93 % (mass), without significant isotope fractionation; (II) The ethanol was converted into CO2 by combustion in excess of oxygen; (III) The carbon isotope ratio of CO2 was analyzed using the isotope ratio mass spectrometry (IRMS). The 18O/16O ratio of the wine water was determined by IRMS using CO2 obtained after equilibration of wine with carbon dioxide. We developed this method in order to get a data bank of isotope ratios for authentic samples of wine as well as for the routine control of many marketed wines. (authors)

  1. Preliminary results from the heavy ions in space experiment

    Science.gov (United States)

    Adams, James H., Jr.; Beahm, Lorraine P.; Tylka, Allan J.

    1992-01-01

    The Heavy Ions In Space (HIIS) experiment has two primary objectives: (1) to measure the elemental composition of ultraheavy galactic cosmic rays, beginning in the tin-barium region of the periodic table; and (2) to study heavy ions which arrive at LDEF below the geomagnetic cutoff, either because they are not fully stripped of electrons or because their source is within the magnetosphere. Both of these objectives have practical as well as astrophysical consequences. In particular, the high atomic number of the ultraheavy galactic cosmic rays puts them among the most intensely ionizing particles in Nature. They are therefore capable of upsetting electronic components normally considered immune to such effects. The below cutoff heavy ions are intensely ionizing because of their low velocity. They can be a significant source of microelectronic anomalies in low inclination orbits, where Earth's magnetic field protects satellites from most particles from interplanetary space. The HIIS results will lead to significantly improved estimates of the intensely ionizing radiation environment.

  2. Permanent GPS Station Sulp: Problems and Preliminary Results

    Science.gov (United States)

    Abrikosov, O.; Zablotskyj, F.; Savchuk, S.

    The permanent GPS station SULP is operating starting from September 2001. GPS observations are carrying out by means of the receiver Trimble 4700 and the antenna Zephyr mounted at the fundamental monument of the Astronomical Observatory of the National University "Lviv Polytechnic". Starting from October 2001, daily and hourly observation files are hosted by OLG Data Center. Analysis of these data is performing by WUT and GOP Analysis Centers. Station SULP was included into episodic GPS campaigns GEODUC (1995) and CEGRN (1994 - 1999, 2001). There- fore, besides the traditional task of providing the permanent high-precision GPS ob- servations for supporting the European networks EUREF and CEGRN, it is planned to use SULP station for the following problems. (1) Investigation of recent movements of the Earth's surface in Carpathian area, particularly in the frames of CERGOP project. (2) Studying of local peculiarities of the atmosphere and constructing of correspond- ing mathematical models. (3) Providing of coordinate data for geodetic activities in the Western Ukraine. GPS data analysis for the mentioned problems is performing by means of GAMIT software. The permanent stations, which surround the Carpathian mountain area, are included into the analysis together with 4 active Ukrainian perma- nent GPS stations. First results show the possibility of the geodetic monitoring based on the permanent station SULP.

  3. Beijing Lightning Network (BLNET): Configuration, Function and Preliminary Results

    Science.gov (United States)

    Qie, X.; Wang, D.; Wang, Y.; Liu, M.; Tian, Y.; Lu, G.

    2015-12-01

    A regional multi-frequency-band lightning detection network in Beijing (BLNET) has been developed for both research and operational purposes. The network is employed in the experiment of Dynamic-microphysical-electrical Processes in Severe Thunderstorms and Lightning Hazards (Storm973), supported by Ministry of Science and Technology as National Key Basic Research Program of China or 973 Program. The network consisted of 16 stations in 2015 covering most part of The "Jing-Jin-Ji" (Beijing-Tianjin-Hebei) metropolis zone, one of the most developed areas in China. Four different sensors, including slow antenna, fast antenna, magnetic antenna, and VHF antenna, are integrated in each station to detect lightning radiation signals in different frequency band. The Chan algorithm and Levenberg-Marquardt method are adopted jointly in the lightning location algorithm. In addition to locate the lightning radiation pulses in two-dimension or three-dimension in different band, the charge source neutralized by the lightning discharge can be retrieved either. The theoretical horizontal error over the network is less than 200 m and the vertical error is less than 500 m over the network. The comparison of total lightning location results with corresponding radar echoes for thunderstorm cases indicates the good performance of BLNET in the severe convection surveillance. The actual two-dimensional location error in VLF/LF band, compared with a ground truth that acquired with a GPS-synchronized high-speed video camera, is about 250 m.

  4. Flight Test 4 Preliminary Results: NASA Ames SSI

    Science.gov (United States)

    Isaacson, Doug; Gong, Chester; Reardon, Scott; Santiago, Confesor

    2016-01-01

    Realization of the expected proliferation of Unmanned Aircraft System (UAS) operations in the National Airspace System (NAS) depends on the development and validation of performance standards for UAS Detect and Avoid (DAA) Systems. The RTCA Special Committee 228 is charged with leading the development of draft Minimum Operational Performance Standards (MOPS) for UAS DAA Systems. NASA, as a participating member of RTCA SC-228 is committed to supporting the development and validation of draft requirements as well as the safety substantiation and end-to-end assessment of DAA system performance. The Unmanned Aircraft System (UAS) Integration into the National Airspace System (NAS) Project conducted flight test program, referred to as Flight Test 4, at Armstrong Flight Research Center from April -June 2016. Part of the test flights were dedicated to the NASA Ames-developed Detect and Avoid (DAA) System referred to as JADEM (Java Architecture for DAA Extensibility and Modeling). The encounter scenarios, which involved NASA's Ikhana UAS and a manned intruder aircraft, were designed to collect data on DAA system performance in real-world conditions and uncertainties with four different surveillance sensor systems. Flight test 4 has four objectives: (1) validate DAA requirements in stressing cases that drive MOPS requirements, including: high-speed cooperative intruder, low-speed non-cooperative intruder, high vertical closure rate encounter, and Mode CS-only intruder (i.e. without ADS-B), (2) validate TCASDAA alerting and guidance interoperability concept in the presence of realistic sensor, tracking and navigational errors and in multiple-intruder encounters against both cooperative and non-cooperative intruders, (3) validate Well Clear Recovery guidance in the presence of realistic sensor, tracking and navigational errors, and (4) validate DAA alerting and guidance requirements in the presence of realistic sensor, tracking and navigational errors. The results will be

  5. The Hyperspectral Thermal Emission Spectrometer (HyTES): Preliminary Results

    Science.gov (United States)

    Hook, Simon; Johnson, William R.; Eng, Bjorn T.; Gunapala, Sarah D.; Lamborn, Andrew U.; Mouroulis, Pantazis, Z.; Mouroulis, Pantazis, Z.; Paine, Christopher G.; Soibel, Alexander; Wilson, Daniel W.

    2011-01-01

    The Hyperspectral Thermal Emission Spectrometer (HyTES) is being developed as part of the risk reduction activities associated with the Hyperspectral Infrared Imager (HyspIRI). HyspIRI is one of the Tier 2 Decadal Survey Missions. HyTES will provide information on how to place the filters on the HyspIRI Thermal Infrared Instrument (TIR) as well as provide antecedent science data. The pushbroom design has 512 spatial pixels over a 50-degree field of view and 256 spectral channels between 7.5 micrometers to 12 micrometers. HyTES includes many key enabling state-of-the-art technologies including a high performance convex diffraction grating, a quantum well infrared photodetector (QWIP) focal plane array, and a compact Dyson-inspired optical design. The Dyson optical design allows for a very compact and optically fast system (F/1.6). It also minimizes cooling requirements due to the fact it has a single monolithic prism-like grating design which allows baffling for stray light suppression. The monolithic configuration eases mechanical tolerancing requirements which are a concern since the complete optical assembly is operated at cryogenic temperatures ((is) approximately 100K). The QWIP allows for optimum spatial and spectral uniformity and provides adequate responsivity or D-star to allow 200mK noise equivalent temperature difference (NEDT) operation across the LWIR passband. Assembly of the system is nearly complete. After completion, alignment results will be presented which show low keystone and smile distortion. This is required to minimize spatial-spectral mixing between adjacent spectral channels and spatial positions. Predictions show the system will have adequate signal to noise for laboratory calibration targets.

  6. The HCV Synthesis Project: Scope, methodology, and preliminary results

    Directory of Open Access Journals (Sweden)

    Scheinmann Roberta

    2008-09-01

    Full Text Available Abstract Background The hepatitis C virus (HCV is hyper-endemic in injecting drug users. There is also excess HCV among non-injection drug users who smoke, snort, or sniff heroin, cocaine, crack, or methamphetamine. Methods To summarize the research literature on HCV in drug users and identify gaps in knowledge, we conducted a synthesis of the relevant research carried out between 1989 and 2006. Using rigorous search methods, we identified and extracted data from published and unpublished reports of HCV among drug users. We designed a quality assurance system to ensure accuracy and consistency in all phases of the project. We also created a set of items to assess study design quality in each of the reports we included. Results We identified 629 reports containing HCV prevalence rates, incidence rates and/or genotype distribution among injecting or non-injecting drug user populations published between January 1989 and December 2006. The majority of reports were from Western Europe (41%, North America (26%, Asia (11% and Australia/New Zealand (10%. We also identified reports from Eastern Europe, South America, the Middle East, and the Caribbean. The number of publications reporting HCV rates in drug users increased dramatically between 1989 and 2006 to 27–52 reports per year after 1998. Conclusion The data collection and quality assurance phases of the HCV Synthesis Project have been completed. Recommendations for future research on HCV in drug users have come out of our data collection phase. Future research reports can enhance their contributions to our understanding of HCV etiology by clearly defining their drug user participants with respect to type of drug and route of administration. Further, the use of standard reporting methods for risk factors would enable data to be combined across a larger set of studies; this is especially important for HCV seroconversion studies which suffer from small sample sizes and low power to examine risk

  7. Thermal plasma treatment of cell-phone waste : preliminary result

    Energy Technology Data Exchange (ETDEWEB)

    Ruj, B. [Central Mechanical Engineering Research Inst., Durgapur (India). Thermal Engineering Group; Chang, J.S.; Li, O.L. [McMaster Univ., Hamilton, ON (Canada). Dept. of Engineering Physics; Pietsch, G. [RWTH Aachen Univ., Aachen (Germany)

    2010-07-01

    The cell phone is an indispensable service facilitator, however, the disposal and recycling of cell phones is a major problem. While the potential life span of a mobile phone, excluding batteries, is over 10 years, most of the users upgrade their phones approximately four times during this period. Cell phone waste is significantly more hazardous than many other municipal wastes as it contains thousands of components made of toxic chemicals and metals like lead, cadmium, chromium, mercury, polyvinyl chlorides (PVC), brominated flame retardants, beryllium, antimony and phthalates. Cell phones also use many expensive rare metals. Since cell phones are made up of plastics, metals, ceramics, and trace other substances, primitive recycling or disposal of cell phone waste to landfills and incinerators creates irreversible environmental damage by polluting water and soil, and contaminating air. In order to minimize releases into the environment and threat to human health, the disposal of cell phones needs to be managed in an environmentally friendly way. This paper discussed a safer method of reducing the generation of syngas and hydrocarbons and metal recovery through the treatment of cell phone wastes by a thermal plasma. The presentation discussed the experiment, with particular reference to sample preparation; experimental set-up; and results four samples with different experimental conditions. It was concluded that the plasma treatment of cell phone waste in reduced condition generates gaseous components such as hydrogen, carbon monoxide, and hydrocarbons which are combustible. Therefore, this system is an energy recovery system that contributes to resource conservation and reduction of climate change gases. 5 refs., 2 tabs., 2 figs.

  8. Elaboration of a chemical decontamination technology: preliminary results

    International Nuclear Information System (INIS)

    background and knowledge evolved at Paks NPP in the course of the chemical decontamination. As a consequence of the long-established achievements, it is practical to develop a procedure based on the methodology of the AP-CITROX (or CORD) technology. It should, however, be noted that the comprehensive analysis of the risk factors, which may be emerged during the application of oxalic acid is unavoidable. In this talk, we will present a brief overview on the fundamental issues of the R and D project focused on the elaboration of the required technology and - based on the results of some recent studies in the fields of solution chemistry, electrochemistry and surface science - summarize the main characteristics of an optimal decontamination procedure. (author)

  9. Simulating lightning into the RAMS model: implementation and preliminary results

    Science.gov (United States)

    Federico, S.; Avolio, E.; Petracca, M.; Panegrossi, G.; Sanò, P.; Casella, D.; Dietrich, S.

    2014-11-01

    This paper shows the results of a tailored version of a previously published methodology, designed to simulate lightning activity, implemented into the Regional Atmospheric Modeling System (RAMS). The method gives the flash density at the resolution of the RAMS grid scale allowing for a detailed analysis of the evolution of simulated lightning activity. The system is applied in detail to two case studies occurred over the Lazio Region, in Central Italy. Simulations are compared with the lightning activity detected by the LINET network. The cases refer to two thunderstorms of different intensity which occurred, respectively, on 20 October 2011 and on 15 October 2012. The number of flashes simulated (observed) over Lazio is 19435 (16231) for the first case and 7012 (4820) for the second case, and the model correctly reproduces the larger number of flashes that characterized the 20 October 2011 event compared to the 15 October 2012 event. There are, however, errors in timing and positioning of the convection, whose magnitude depends on the case study, which mirrors in timing and positioning errors of the lightning distribution. For the 20 October 2011 case study, spatial errors are of the order of a few tens of kilometres and the timing of the event is correctly simulated. For the 15 October 2012 case study, the spatial error in the positioning of the convection is of the order of 100 km and the event has a longer duration in the simulation than in the reality. To assess objectively the performance of the methodology, standard scores are presented for four additional case studies. Scores show the ability of the methodology to simulate the daily lightning activity for different spatial scales and for two different minimum thresholds of flash number density. The performance decreases at finer spatial scales and for higher thresholds. The comparison of simulated and observed lighting activity is an immediate and powerful tool to assess the model ability to reproduce the

  10. The ''EVA'' trial: evaluation of the efficacy of diagnostic methods (mammography, ultrasound, MRI) in the secondary and tertiary prevention of familial breast cancer. Preliminary results after the first half of the study period; Die ''EVA''-Studie: Evaluierung der Leistungsfaehigkeit diagnostischer Verfahren (Mammographie, Sonographie, MRT) zur sekundaeren und tertiaeren Praevention des familiaeren Mammakarzinoms - Zwischenergebnisse nach der ersten Haelfte der Foerderungsperiode

    Energy Technology Data Exchange (ETDEWEB)

    Kuhl, C.K.; Schrading, S.; Morakkabati, N.; Leutner, C.; Schild, H. [Radiologische Universitaetsklinik, Bonn (Germany); Weigel, S.; Tombach, B.; Nordhoff, D.; Heindel, W. [Inst. fuer Klinische Radiologie der Univ. Muenster, Muenster (Germany); Nuessle-Kuegele, K.; Arand, B.; Rieber, A.; Brambs, H.J. [Abt. fuer Roentgendiagnostik der Univ. Ulm, Ulm (Germany); Sittek, H.; Reiser, M. [Inst. fuer Klinische Radiologie des Klinikums der Univ. Muenchen-Grosshadern, Muenchen (Germany)

    2005-06-01

    Purpose: to investigate the respective diagnostic accuracies of the different breast imaging modalities, i. e., mammography (Mx), high-frequency breast ultrasound (US), and dynamic contrast-enhanced breast (MRI) regarding the early diagnosis of familial (hereditary) breast cancer. Materials and methods: a prospective, non-randomized controlled clinical multi-center trial is performed at 4 academic tertiary care centers in Germany (Ulm, Muenchen/Grosshadern, Muenster and Bonn) for a total period of 4 years, sponsored by the German Cancer Aid. The protocol consists of semiannual clinical visits and breast ultrasound, and annual bilateral two-view Mx, US and MRI. Imaging studies were first analyzed independently, then Mx was read in conjunction with US, followed by Mx combined with MRI, and finally, all three imaging modalities were read in synopsis. We present the concept and first results of this trial. Results: so far, 748 screening rounds are available for analysis in 613 women. A total of 12 breast cancers have been identified, with 11/12 cases in the pTis or pT1/N0 stage. The mean size of detected invasive cancers was 7 mm. A total of 19 benign lesions were biopsied due to false-positive imaging diagnoses. The breast cancer detection rates were: Mx: 5/12 (42%), US 3/12 (25%), MRI 10/12 (83%), and the positive predictive values: Mx 5/17 (29%), US 3/15 (30%), and MRI 10/23 (43%). Conclusion: the preliminary data suggest that early diagnosis of familial breast cancer is feasible by intensified surveillance, in particular with the addition of MRI. (orig.)

  11. EM techniques for archaeological laboratory experiments: preliminary results

    Science.gov (United States)

    Capozzoli, Luigi; De Martino, Gregory; Giampaolo, Valeria; Raffaele, Luongo; Perciante, Felice; Rizzo, Enzo

    2015-04-01

    model. The integration of electric and electromagnetic data allowed us to overcome the limits of each technique, especially in terms of resolution and depth, in humid/saturated conditions was investigated and the effectiveness of three-dimensional acquisitions was studied to better explore archeological sites and reduce the uncertainties related on the interpretation of geophysical analysis. The complexity of the relationship between archaeological features in the subsoil and their geophysical response requires efforts in the interpretation of resulting data. Reference Campana S. and Piro, S., (2009): Seeing the unseen - Geophysics and landscape archaeology., CRC Press, London, 2. No. of pages: 376. ISBN: 978-0-415-44721-8. Conyers, L. and Goodman, D., (1997): Ground-Penetrating Radar: An Introduction for Archaeologists. Walnut Creek, Calif.: AltaMira Press. Davis, J.L. and Annan, A.P. (1989): Ground-penetrating radar for high-resolution mapping of soil and rock stratigraphy. Geophysical Prospecting, 37, 531-551.

  12. Dating of polyhalite and langbeinite: preliminary results from German Zechstein

    Science.gov (United States)

    Neubauer, Franz; Schorn, Anja; Leitner, Christoph; Genser, Johann

    2013-04-01

    formation temperatures are given between 57.1 ° C or more commonly 83 ° C (e.g. Neitzel, 1992 and references therein), is mined as potash ore at the German Zechstein deposits. Neitzel (1992) summarized two main types of langbeinite formation (1) from kainite and halite (due to thermal metamorphism) and (2) from sylvinitic Hartsalz (= mixture of sylvite, kieserite and halite) due to solution metamorphism. The mineral might also form by decomposition of polyhalite to langbeinite and anhydrite during prograde metamorphism. In the following, we discuss the first successful results of polyhalite and langbeinite dating in Zechstein salts of Germany (Morsleben, Neuhof). Extremely fine-grained (grain sizes International Journal of Earth Sciences, DOI 10.1007/s00531-012-0836-6. Neitzel, U., 1992. 100 Jahre Langbeinit. Kali und Steinsalz, 11/1, 7-13. Renne, P. R., Sharp, W. D. Montañez, I. P., Becker, R. A., Zierenberg, R. A., 2001. 40Ar/39Ar dating of Late Permian evaporites, southeastern New Mexico, USA. Earth and Planetary Science Letters, 193, 539-547. Warren, J. K., 2006. Evaporites: Sediments, Resources and Hydrocarbons. Springer, Berlin Heidelberg, 1035 p. Wollmann, G., 2010. Crystallization Fields of Polyhalite and its Heavy Metal Analogues. Ph.D. thesis, University Bergakademie Freiberg. Wollmann, G., Freyer, D., Voigt, W., 2008. Polyhalite and its analogous triple salts. Monatshefte für Chemie, 139, 739-745.

  13. Bisphosphonates in the adjuvant treatment of cancer: experimental evidence and first clinical results

    OpenAIRE

    I.J. Diel; Mundy, G R; ,

    2000-01-01

    Several animal models, as well as a number of cell culture experiments, indicate a prophylactic effect of bisphosphonates in respect of subsequent bone metastasis. Moreover, in preliminary clinical trials involving patients with advanced breast cancer and local or remote metastases, biophosphonates produced a reduction in new skeletal metastases. This overview summarizes and discusses the results of the latest investigations. It opens with a section on the pathophysiology of bone metastasis, ...

  14. Very accelerated radiation therapy: preliminary results in locally unresectable head and neck carcinomas

    International Nuclear Information System (INIS)

    Purpose: To report preliminary results of a very accelerated radiation therapy Phase I/II trial in locally advanced head and squamous cell carcinomas (HNSCC). Methods and Materials: Between 01/92 and 06/93, 35 patients with an unresectable HNSCC were entered in this study. Thirty-two (91%) had Stage IV, and 3 had Stage III disease. The mean nodal diameter, in patients with clinically involved nodes (83%), was 6.3 cm. The median Karnovsky performance status was 70. The treatment consisted of a twice daily schedule (BID) giving 62 Gy in 20 days. Results: In all cases, confluent mucositis was observed, which started about day 15 and resolved within 6 to 10 weeks. Eighty percent of patients had enteral nutritional support. The nasogastric tube or gastrostomy was maintained in these patients for a mean duration of 51.8 days. Eighteen patients (53%) were hospitalized during the course of treatment due to a poor medical status or because they lived far from the center (mean 25 days). Nineteen patients (56%) (some of whom were initially in-patients) were hospitalized posttreatment for toxicity (mean 13 days). Five patients (15%) were never hospitalized. During the follow-up period, 12 local and/or regional failures were observed. The actuarial 18-month loco-regional control rate was 59% (95% confidence interval, 45-73%). Conclusions: The dramatic shortening of radiation therapy compared to conventional schedules in our series of very advanced HNSCC resulted in: (a) severe acute mucosal toxicity, which was manageable but required intensive nutritional support in all cases; and (b) high loco-regional response rates, strongly suggesting that the time factor is likely to be critical for tumor control in this type of cancer

  15. Decision-Making in Flight with Different Convective Weather Information Sources: Preliminary Results

    Science.gov (United States)

    Latorella, Kara A.; Chamberlain, James P.

    2004-01-01

    This paper reports preliminary and partial results of a flight experiment to address how General Aviation (GA) pilots use weather cues to make flight decisions. This research presents pilots with weather cue conditions typically available to GA pilots in visual meteorological conditions (VMC) and instrument meteorological conditions (IMC) today, as well as in IMC with a Graphical Weather Information System (GWIS). These preliminary data indicate that both VMC and GWIS-augmented IMC conditions result in better confidence, information sufficiency and perceived performance than the current IMC condition. For all these measures, the VMC and GWIS-augmented conditions seemed to provide similar pilot support. These preliminary results are interpreted for their implications on GWIS display design, training, and operational use guidelines. Final experimental results will compare these subjective data with objective data of situation awareness and decision quality.

  16. 75 FR 67689 - Stainless Steel Bar From Brazil: Preliminary Results of Antidumping Duty Administrative Review

    Science.gov (United States)

    2010-11-03

    ... Brazil. See Antidumping Duty Orders: Stainless Steel Bar from Brazil, India and Japan, 60 FR 9661... Steel Bar From Brazil: Preliminary Results of Antidumping Duty Administrative Review, 74 FR 10022 (March... market. \\2\\ These results were unchanged in the final results of review (Stainless Steel Bar From...

  17. Acute toxicity of postoperative radiochemotherapy with amifostine vs radiochemotherapy alone in head and neck cancer patients. Preliminary results of a randomized trial; Nebenwirkungen einer postoperativen Radiochemotherapie mit Amifostin versus alleiniger Radiochemotherapie bei Kopf-Hals-Tumoren. Vorlaeufige Ergebnisse einer prospektiv randomisierten Untersuchung

    Energy Technology Data Exchange (ETDEWEB)

    Vacha, P.; Marx, M.; Engel, A.; Richter, E.; Feyerabend, T. [Medizinische Univ. Luebeck (Germany). Klinik fuer Strahlentherapie und Nuklearmedizin

    1999-11-01

    Purpose: Experimental and clinical data suggest a reduction of radiation-induced acute toxicity by amifostine. We investigated this issue in a randomized trial comparing radiochemotherapy (RCT) versus radiochemotherapy and amifostine (RCT+A) in patients with head and neck cancer. Patients and methods: Forty-seven patients with pharyngeal or laryngeal cancer (T{sub 1-2}N{sub 1-2}G{sub 3},T{sub 3-4}N{sub 0-2}G{sub 1-3}) were randomized to receive RCT alone (21 patients) or RCT+A (21 patients). Patients were irradiated up to 60 Gy (R{sub 0}) or 70 Gy (R{sub 1/2}). Chemotherapy consisted of 70 mg/m{sup 2} carboplatin and was administered over 5 days in the 1st and 5th week of the radiotherapy course. 250 mg amifostine were applied daily just before each radiotherapy session. Acute toxicity was evaluated according to the Common Toxicity Criteria (CTC). As for xerostomia no patients with laryngeal cancer were assessed because in these cases only small volumes of the salivary glands were within the treatment volume. To evaluate the overall toxicity a summarized CTC score of all observed side effects was calculated. Results: Forty-two patients were evaluable. Clinical characteristics (age, sex, Karnofsky index, tumor-staging) were well balanced in both treatment groups. Amifostine provided reduction in xerostomia and mucositis. Conclusions: According to our preliminary results amifostine has a radioprotective effect on salivary glands. Mucositis can be reduced during radiochemotherapy. At this point of patient accrual the difference between both groups are statistically not significant. To improve the radioprotective effects of amifostine in clinical practice the application of a higher dose (>250 mg) seems to be necessary. (orig.) [German] Ziel: Diese Untersuchung soll die Frage beantworten, ob bei der postoperativen Radiochemotherapie von Patienten mit HNO-Tumoren eine zusaetzliche Amifostin-Medikation Ausmass und Haeufigkeit akuter Strahlenreaktionen vermindert

  18. Treatment results in males with breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Pakisch, B. [Dept. of Radiotherapy, Karl Franzens Univ. of Graz (Austria); Stoeger, H. [Dept. of Clinical Oncology, Karl Franzens Univ. of Graz (Austria); Poschauko, H. [Dept. of Radiotherapy, Karl Franzens Univ. of Graz (Austria); Samonigg, H. [Dept. of Clinical Oncology, Karl Franzens Univ. of Graz (Austria); Bauernhofer, T. [Dept. of Clinical Oncology, Karl Franzens Univ. of Graz (Austria); Pojer, E. [Dept. of Clinical Oncology, Karl Franzens Univ. of Graz (Austria); Leitner, H. [Dept. of Radiotherapy, Karl Franzens Univ. of Graz (Austria); Stuecklschweiger, G. [Dept. of Radiotherapy, Karl Franzens Univ. of Graz (Austria); Peichl, K.H. [Dept. of Radiotherapy, Karl Franzens Univ. of Graz (Austria); Quehenberger, F. [Dept. of Statistics and Documentation, Karl Franzens Univ. of Graz (Austria); Hackl, A. [Dept. of Radiotherapy, Karl Franzens Univ. of Graz (Austria)

    1995-08-01

    Because cancer of the male breast is rare knowledge about its biology and behavior is essentially due to a compilation of pooled experiences. Hence, a continued report of cases appears to be important. Therefore a retrospective review of patients suffering from male breast cancer was carried out. Twenty-four evaluable cases were analyzed. Eight patients (1 patient with bilateral Stage I carcinoma was included) were in Stage I, 7 in Stage II, 2 in Stage IIIa, 4 in Stage IIIb, and 3 in Stage IV. Of 23 patients who were treated with mastectomy, 22 had modified radical mastectomy and postoperative irradiation to the chest wall as well as to the peripheral lymphatic areas in most cases. One patient underwent radical mastectomy. Another patient had an excision biopsy only, followed by irradiation. One of 24 patients received tamoxifen; another received cyclophosphamide, methotrexate, 5-fluorouracil, prednisone (CMF) regimen in an adjuvant setting. Local recurrence developed in one of 23 (4%) patients treated with mastectomy and radiation therapy to the chest wall and peripheral lymphatics. Four (17%) patients developed distant metastases. The 5-year overall survival (Kaplan-Maier) was 90% for the entire group, 100% for patients in Stage I-III disease, and 60% in Stage IV disease (P = < 0.005). As observed in former reports the stage of disease at initial presentation seems to be a parameter that significantly contributes to survival in male breast cancer patients. To what extent improved local control by adequate local therapy, such as surgery and postoperative radiotherapy, may improve overall survival remains to be discussed. (orig.)

  19. Modelled and Observed Diurnal SST Signals: "SSTDV:R.EX.-IM.A.M." Project Preliminary Results

    DEFF Research Database (Denmark)

    Karagali, Ioanna; Høyer, Jacob; LeBorgne, Pierre;

    2013-01-01

    This study presents some of the preliminary results from the ESA Support To Science Element (STSE) funded project on the Diurnal Variability of the Sea Surface Temperature, regarding its Regional Extend and Implications in Atmospheric Modelling (SSTDV:R.EX.–IM.A.M.). During this phase of the proj......This study presents some of the preliminary results from the ESA Support To Science Element (STSE) funded project on the Diurnal Variability of the Sea Surface Temperature, regarding its Regional Extend and Implications in Atmospheric Modelling (SSTDV:R.EX.–IM.A.M.). During this phase...

  20. The effect of parental involvement in CBT of anxious children: Preliminary results from a RCT study

    DEFF Research Database (Denmark)

    Esbjørn, Barbara Hoff; Breinholst, Sonja; Reinholdt-Dunne, Marie Louise;

    2011-01-01

    Esbjørn, B. H., Breinholst, S., Reinholdt-Dunne, M. L., & Leth, I. (2011). The effect of parental involvement in CBT of anxious children: Preliminary results from a RCT study. Poster accepted for the Association for Behavioral and Cognitive Therapies, Toronto, Canada.......Esbjørn, B. H., Breinholst, S., Reinholdt-Dunne, M. L., & Leth, I. (2011). The effect of parental involvement in CBT of anxious children: Preliminary results from a RCT study. Poster accepted for the Association for Behavioral and Cognitive Therapies, Toronto, Canada....

  1. 76 FR 2655 - Honey From Argentina: Preliminary Results of Antidumping Duty Administrative Review

    Science.gov (United States)

    2011-01-14

    ...: Honey From Argentina, 66 FR 63672 (December 10, 2001). On December 1, 2009, the Department published in... Memorandum; see e.g., Honey from Argentina: Final Results of Antidumping Duty Administrative Review, 70 FR... to Patagonik. See, e.g., Honey From Argentina: Preliminary Results of New Shipper Review, 71 FR...

  2. Ethnicity and prostate cancer in Southern Nigeria: A preliminary report

    Directory of Open Access Journals (Sweden)

    Monday K Sapira

    2015-01-01

    Full Text Available Introduction: The natural history of prostate cancer varies among patients. The aim of this study is to detect any variations in clinical and pathological characteristics of the tumor in patients from different ethnic groups in Southern Nigeria. Patients and Methods: Consecutive patients who presented with features of prostatic diseases at the Urology Units of University of Port Harcourt Teaching Hospital, Port Harcourt and Nnamdi Azikiwe University Teaching Hospital, Nnewi, were evaluated prospectively with history, physical examination, and relevant investigations using a proforma. Data obtained were collated and analyzed statistically using the Chi-square test and Microsoft Excel. Results: Of 187 patients studied, 169 were analyzed. Eighty-six were Ibos, 31 Ijaws, 25 Ikwerres, and 12 Ogonis. Two were from each Etche, Urhobo, Opobo, and Effik; 4 from Andoni, and 3 Ibibio. Fifty-seven (66.3% Ibos presented with the disease at higher ages (70–80 years than 19 (61.3% Ijaws and 11 (91.7% Ogonis. These age differences were statistically significant with 95% and 99.9% confidence, respectively. All cases were adenocarcinomas. Clinical features, pattern of serum prostate-specific antigen levels, grades of the tumors, tumor metastases, and complications were similar for all ethnic groups. Although more Ibos had tumors with relatively more aggressive metastatic features, there was no statistical significance. Conclusion: Clinical and pathological features of adenocarcinoma of the prostate in Ibos, Ikwerres, Ijaws, and Ogonis were found to be similar. However, Ibos presented with the disease at older ages than Ijaws and Ogonis.

  3. Nb/NiCu bilayers in single and stacked superconductive tunnel junctions: preliminary results

    International Nuclear Information System (INIS)

    We present preliminary experimental results concerning both single and stacked tunnel junctions in which one of the electrodes was formed by a superconductor/ferromagnet (S/F) bi-layer. In particular, in the stacked configuration a Nb/NiCu bi-layer was used as the intermediate electrode, and it was probed by tunneling on both sides. Tunnel junctions have been characterized in terms of current-voltage characteristics (IVC), and differential conductance. Preliminary steady-state injection-detection measurements performed in the stacked devices at T=4.2 K are also presented and discussed

  4. Nb/NiCu bilayers in single and stacked superconductive tunnel junctions: preliminary results

    Science.gov (United States)

    Pepe, G. P.; Ruotolo, A.; Parlato, L.; Peluso, G.; Ausanio, G.; Carapella, G.; Latempa, R.

    2004-05-01

    We present preliminary experimental results concerning both single and stacked tunnel junctions in which one of the electrodes was formed by a superconductor/ferromagnet (S/F) bi-layer. In particular, in the stacked configuration a Nb/NiCu bi-layer was used as the intermediate electrode, and it was probed by tunneling on both sides. Tunnel junctions have been characterized in terms of current-voltage characteristics (IVC), and differential conductance. Preliminary steady-state injection-detection measurements performed in the stacked devices at T=4.2K are also presented and discussed.

  5. Nb/NiCu bilayers in single and stacked superconductive tunnel junctions: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Pepe, G.P. E-mail: ruotolo_antonio@tin.it; Ruotolo, A.; Parlato, L.; Peluso, G.; Ausanio, G.; Carapella, G.; Latempa, R

    2004-05-01

    We present preliminary experimental results concerning both single and stacked tunnel junctions in which one of the electrodes was formed by a superconductor/ferromagnet (S/F) bi-layer. In particular, in the stacked configuration a Nb/NiCu bi-layer was used as the intermediate electrode, and it was probed by tunneling on both sides. Tunnel junctions have been characterized in terms of current-voltage characteristics (IVC), and differential conductance. Preliminary steady-state injection-detection measurements performed in the stacked devices at T=4.2 K are also presented and discussed.

  6. Do signal transduction cascades influence survival in triple-negative breast cancer? A preliminary study

    Science.gov (United States)

    Mumm, Jan-Niclas; Kölbl, Alexandra C; Jeschke, Udo; Andergassen, Ulrich

    2016-01-01

    Background Triple-negative breast cancer (TNBC) is a rather aggressive form of breast cancer, comprised by early metastasis formation and reduced overall survival of the affected patients. Steroid hormone receptors and the human epidermal growth factor receptor 2 are not overexpressed, limiting therapeutic options. Therefore, new treatment options have to be investigated. The aim of our preliminary study was to detect coherences between some molecules of intracellular signal transduction pathways and survival of patients with TNBC, in order to obtain some hints for new therapeutical solutions. Methods Thirty-one paraffin-embedded tumor tissue samples, which were determined to be negative for steroid hormone receptors as well as human epidermal growth factor receptor 2, were immunohistochemically stained for a number of signal transduction molecules from several signaling pathways. β-Catenin, HIF1α, MCL, Notch1, LRP6, XBP1, and FOXP3 were stained with specific antibodies, and their staining was correlated with patient survival by Kaplan–Meier analyses. Results Only two of the investigated molecules have shown correlation with overall survival. Cytoplasmic staining of HIF1α and centro-tumoral lymphocyte FOXP3 staining showed statistically significant correlations with survival. Conclusion The coherence of signal transduction molecules with survival of patients with TNBC is still controversially discussed in the literature. Our study comprises one more mosaic stone in the elucidation of these intracellular processes and their influences on patient outcome. Lots of research still has to be done in this field, but it would be worthwhile as it may offer new therapeutic targets for a group of patients with breast cancer, which is still hard to treat. PMID:27307757

  7. Preliminary results of the round-robin testing of F82H

    Energy Technology Data Exchange (ETDEWEB)

    Shiba, K.; Yamanouchi, N.; Tohyama, A.

    1996-10-01

    Preliminary results of metallurgical, physical and mechanical properties of low activation ferritic steel F82H (IEA heat) were obtained in the round-robin test in Japan. The properties of IEA heat F82H were almost the same as the original F82H.

  8. 78 FR 34648 - Citric Acid and Certain Citrate Salts: Preliminary Results of Countervailing Duty Administrative...

    Science.gov (United States)

    2013-06-10

    ... International Trade Administration Citric Acid and Certain Citrate Salts: Preliminary Results of Countervailing... review of the countervailing duty (CVD) order on citric acid and citrate salts from the People's Republic... (202) 482-1503. Scope of the Order The merchandise subject to the order is citric acid and...

  9. 78 FR 34338 - Citric Acid and Certain Citrate Salts From Canada: Preliminary Results of Antidumping Duty...

    Science.gov (United States)

    2013-06-07

    ...: Antidumping Duty Orders, 74 FR 25703 (May 29, 2009) (Citric Acid Duty Orders). Methodology The Department has... International Trade Administration Citric Acid and Certain Citrate Salts From Canada: Preliminary Results of... administrative review of the antidumping duty order on citric acid and certain citrate salts (citric acid)......

  10. Three-dimensional Simulations of Thermonuclear Detonation with α-Network: Numerical Method and Preliminary Results

    Science.gov (United States)

    Khokhlov, A.; Domínguez, I.; Bacon, C.; Clifford, B.; Baron, E.; Hoeflich, P.; Krisciunas, K.; Suntzeff, N.; Wang, L.

    2012-07-01

    We describe a new astrophysical version of a cell-based adaptive mesh refinement code ALLA for reactive flow fluid dynamic simulations, including a new implementation of α-network nuclear kinetics, and present preliminary results of first three-dimensional simulations of incomplete carbon-oxygen detonation in Type Ia Supernovae.

  11. 78 FR 15699 - Certain Frozen Warmwater Shrimp From the Socialist Republic of Vietnam: Preliminary Results of...

    Science.gov (United States)

    2013-03-12

    ..., available in Certain Frozen Warmwater Shrimp From Brazil, India, the People's Republic of China, Thailand... Warmwater Shrimp From the Socialist Republic of Vietnam: Preliminary Results of Administrative Review, 77 FR... FR 55800 (September 11, 2012) (``AR6 VN Shrimp''). \\9\\ In AR5 VN Shrimp, the Department found...

  12. 77 FR 7128 - Low Enriched Uranium From France: Preliminary Results of Antidumping Duty Changed Circumstances...

    Science.gov (United States)

    2012-02-10

    ... Determination and Notice of Countervailing Duty Order: Low Enriched Uranium From France, 67 FR 6689 (February 13..., 77 FR 1059 (January 9, 2012) (CCR Initiation Notice). DATES: Effective Date: February 10, 2012. FOR... International Trade Administration Low Enriched Uranium From France: Preliminary Results of Antidumping...

  13. Longitudinal Twin Study of Early Reading Development in Three Countries: Preliminary Results.

    Science.gov (United States)

    Byrne, Brian; Delaland, Cara; Fielding-Barnsley, Ruth; Quain, Peter; Samuelsson, Stefan; Hoien, Torleiv; Corley, Robin; DeFries, John C.; Wadsworth, Sally; Willcutt, Erik; Olson, Richard K.

    2002-01-01

    Preliminary results from data on 146 Australian, 284 American, and 70 Norwegian preschool twins indicate reliable genetic influences on phonological awareness and memory and learning. Vocabulary, grammar, and morphology showed significant shared environment and negligible genetic effects. A print knowledge composite showed genetic and shared…

  14. 78 FR 49256 - Certain Pasta From Italy: Preliminary Results of the Countervailing Duty Administrative Review; 2011

    Science.gov (United States)

    2013-08-13

    ... International Trade Administration Certain Pasta From Italy: Preliminary Results of the Countervailing Duty... the countervailing duty order on certain pasta from Italy. The period of review (``POR'') is January 1.... SUPPLEMENTARY INFORMATION: Scope of the Order The scope of the order consists of certain pasta from Italy....

  15. 76 FR 48125 - Certain Pasta From Italy: Notice of Preliminary Results of Antidumping Duty Administrative Review

    Science.gov (United States)

    2011-08-08

    ...: Certain Pasta From Italy, 61 FR 38547 (July 24, 1996). \\2\\ See Antidumping or Countervailing Duty Order... Administrative Review, 76 FR 6601, February 7, 2011 (``Pasta Thirteen''); see also Notice of Preliminary Results... the Sixth Administrative Review of the Antidumping Duty Order on Certain Pasta from Italy, 68 FR...

  16. 78 FR 70267 - Multilayered Wood Flooring From the People's Republic of China: Preliminary Results of...

    Science.gov (United States)

    2013-11-25

    ... new deadline falls on a non-business day, in accordance with the Department's practice, the deadline will become the next business day. The revised deadline for the preliminary results of this review is... Wood Co., Ltd........ 4.77 Fujian Wuyishan Werner Green Industry 4.77 Co., Ltd. Fusong Jinlong...

  17. 78 FR 38941 - Honey From the People's Republic of China: Preliminary Results and Partial Rescission of...

    Science.gov (United States)

    2013-06-28

    ... International Trade Administration Honey From the People's Republic of China: Preliminary Results and Partial... Order The products covered by the order are natural honey, artificial honey containing more than 50 percent natural honey by weight, preparations of natural honey containing more than 50 percent...

  18. 76 FR 19315 - Certain Orange Juice From Brazil: Preliminary Results of Antidumping Duty Administrative Review...

    Science.gov (United States)

    2011-04-07

    ... certain orange juice from Brazil. See Antidumping Duty Order: Certain Orange Juice from Brazil, 71 FR... Antidumping Duty Order; Frozen Concentrated Orange Juice from Brazil, 52 FR 16426 (May 5, 1987). Therefore... International Trade Administration Certain Orange Juice From Brazil: Preliminary Results of Antidumping...

  19. 77 FR 21724 - Certain Orange Juice From Brazil: Preliminary Results of Antidumping Duty Administrative Review...

    Science.gov (United States)

    2012-04-11

    ... Antidumping Duty Order; Frozen Concentrated Orange Juice from Brazil, 52 FR 16426 (May 5, 1987). Therefore... of Critical Circumstances: Certain Orange Juice from Brazil, 71 FR 2183 (Jan. 13, 2006). As noted... International Trade Administration Certain Orange Juice From Brazil: Preliminary Results of Antidumping...

  20. 77 FR 32503 - Certain Polyester Staple Fiber From Taiwan: Preliminary Results of Antidumping Duty...

    Science.gov (United States)

    2012-06-01

    ... Review, 75 FR 39208 (July 8, 2010). \\2\\ See Initiation of Antidumping and Countervailing Duty Administrative Reviews and Requests for Revocation in Part, 76 FR 37781 (June 28, 2011). On January 30, 2012, in...: Extension of Time Limit for Preliminary Results of Antidumping Duty Administrative Review, 77 FR...

  1. Preliminary Results from Second Phase Sea Testing of the Wave Dragon Prototype Wave Energy Converter

    DEFF Research Database (Denmark)

    Soerensen, Hans Chr.; Tedd, James; Friis-Madsen, Erik;

    2006-01-01

    In March 2006 the prototype Wave Dragon has been redeployed to a more energetic site in Nissum Bredning an inland sea in Western Denmark. This has followed a period of renovation of many aspects of the device which have resulted in 20% higher energy output. This paper describes the preliminary...

  2. Gas enhanced magnetic resonance angiography of the cerebrum using carbon dioxide and oxygen - preliminary results

    DEFF Research Database (Denmark)

    Pedersen, Mads Møller; Hansen, Kristoffer Lindskov; Ohlhues, Anders;

    meninges may obscure the signal from the arteries of interest. It is known that oxygen enhances the T1-weighted signal and that carbon dioxide increases the arterial blood flow. This paper presents preliminary results of gas enhanced MRA using combinations of atmospheric air, O2 and CO2. Subjects and...

  3. Preliminary results of a proficiency testing of industrial CT scanners using small polymer items

    DEFF Research Database (Denmark)

    Angel, Jais Andreas Breusch; Cantatore, Angela; De Chiffre, Leonardo

    2012-01-01

    This work presents preliminary results concerning a proficiency testing for intercomparison of industrial CT scanners. Two audit items, similar to common industrial parts, were selected for circulation. The two items were a single polymer complex geometry part and a simple geometry item made of two...

  4. 75 FR 27302 - Chlorinated Isocyanurates From the People's Republic of China: Preliminary Results and Partial...

    Science.gov (United States)

    2010-05-14

    ... represent actual country-wide, publicly-available information on tax-exclusive electricity rates charged to... regression-based wage rate as reported on Import Administration's Web site.\\23\\ Because this regression-based... rates are above de minimis. We invite interested parties to comment on these preliminary results....

  5. 77 FR 73615 - Lightweight Thermal Paper From Germany; Preliminary Results of Antidumping Duty Administrative...

    Science.gov (United States)

    2012-12-11

    ... Thermal Paper from Germany and the People's Republic of China, 73 FR 70959 (November 24, 2008) (Orders...: Assessment of Antidumping Duties, 68 FR 23954 (May 6, 2003). Assessment of Antidumping Duties We intend to... International Trade Administration Lightweight Thermal Paper From Germany; Preliminary Results of...

  6. 76 FR 26241 - Polyethylene Retail Carrier Bags From Thailand: Extension of Time Limit for Preliminary Results...

    Science.gov (United States)

    2011-05-06

    ..., 75 FR 60076 (September 29, 2010). The preliminary results of this administrative review are currently... International Trade Administration Polyethylene Retail Carrier Bags From Thailand: Extension of Time Limit for... polyethylene retail carrier bags from Thailand for the period August 1, 2009, through July 31, 2010....

  7. Preliminary Study of Stereotactic Radiotherapy for Lung Cancer

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    From March 1997 to November 1999, 45 patients with lung cancer were treated by astereotactic radiotherapy, with 15 cases treated by a stereotactic radiotherapy alone, and 30 cases by the external radiotherapy plus stereotactic radiotherapy. The clinical target volume was 1.89-187. 26 cm3 with the median being 18. 17 cm3. The doses of plan target volume (PTV) edge was 16-30 Gy/2-3 times and the doses of center was 120 % to 150 % of PTV edge doses. The overall response rate was 84.4 % (38/45), with 11 complete response (CR) and 27 partial response (PR). This study confirmed that the stereotactic radiotherapy is a safe and effective therapy for lung cancer. For those early-stage patients who can tolerate neither operation nor even conventional radiotherapy for various reasons, it can both achieve therapeutic purpose and improve quality of life.

  8. A dual-modality photoacoustic and ultrasound imaging system for noninvasive sentinel lymph node detection: preliminary clinical results

    Science.gov (United States)

    Erpelding, Todd N.; Garcia-Uribe, Alejandro; Krumholz, Arie; Ke, Haixin; Maslov, Konstantin; Appleton, Catherine; Margenthaler, Julie; Wang, Lihong V.

    2014-03-01

    Sentinel lymph node biopsy (SLNB) has emerged as an accurate, less invasive alternative to axillary lymph node dissection, and it has rapidly become the standard of care for patients with clinically node-negative breast cancer. The sentinel lymph node (SLN) hypothesis states that the pathological status of the axilla can be accurately predicted by determining the status of the first (i.e., sentinel) lymph nodes that drain from the primary tumor. Physicians use radio-labeled sulfur colloid and/or methylene blue dye to identify the SLN, which is most likely to contain metastatic cancer cells. However, the surgical procedure causes morbidity and associated expenses. To overcome these limitations, we developed a dual-modality photoacoustic and ultrasound imaging system to noninvasively detect SLNs based on the accumulation of methylene blue dye. Ultimately, we aim to guide percutaneous needle biopsies and provide a minimally invasive method for axillary staging of breast cancer. The system consists of a tunable dye laser pumped by a Nd:YAG laser, a commercial ultrasound imaging system (Philips iU22), and a multichannel data acquisition system which displays co-registered photoacoustic and ultrasound images in real-time. Our clinical results demonstrate that real-time photoacoustic imaging can provide sensitive and specific detection of methylene blue dye in vivo. While preliminary studies have shown that in vivo detection of SLNs by using co-registered photoacoustic and ultrasound imaging is feasible, further investigation is needed to demonstrate robust SLN detection.

  9. 99mTc somatostatin imaging for detection of somatostatin receptor. A preliminary result

    International Nuclear Information System (INIS)

    Radiolabeled somatostatin analogs are used with great success in vivo for scintigraphy of somatostatin receptor and are of interest for clinical routine application as 111In octreotide is not optimal with respect to radionuclide properties, availability and cost. Objective: To validate the utility of 99mTc-somatostatin receptor (99mTcSR) imaging in clinical practice Methods: Twelve patients (5 M, 7 F, age range 2-75 yr) were studied. Three normal subject were studied for biodistribution of 99mTcSR. Nine patients had histological diagnostic of tumors (lung cancer 3), neuroblastoma, (2), pheochromocytoma (1), lymphoma (2), (1 with Hodgkin's disease (HD) and 1 with non Hodgkin's lymphoma (NHL)), meningioma (1). The 99mTC-SR was labeling following the method [99mTc (H2O)3(CO)3] + (J.Nucl Med 1999;40:1913-1917), and adding the commercially available octreotide (sandostatin) with DTPA as a chelator and tricine as a coligand. Patients were injected with 20-25 99mTc SR, and the scintigraphies were obtaining 1-5-24 hrs according to routine whole body scanning. The 99mTc SR was cleared from the circulation by the kidney and liver. Liver activity is excreted in the biliary system. The images at 4 hours show low activity in the G.I. tract. Scintigraphic images were evaluated and scored according to a) image acceptability: (1:excellent, 2:good, 3:fair, 4:poor), b) lesion uptake: (1:minimal,2:moderate,3:high), by 2 nuclear medicine physicians independently. Criteria for 99mTc RS positive finding were a focally increased uptake that persistent or increased over time, in these cases SPECT was always performed at 5 hours. Results: According to the scintigraphics finding the patients with tumors were divided in: 1) negative studies: 4 patients showed not abnormal uptake, and 2) positive studies: five patients (55,5%) showed moderate or high uptake, at 1-5-24 hours planar imaging. In these patients SPECT images at 5 hours identify the lesions with more certainty. According to

  10. Ziconotide in severe, drug-resistant cancer pain. preliminary experience

    OpenAIRE

    Angelo Lavano

    2008-01-01

    The Author reports the case of ziconotide intrathecal treatment in three terminal cancer patients, with nociceptive and neuropathic pain, unresponsive to the treatment with intrathecal opioid and adjuvant drugs. An external pump for continuous subarachnoid infusion was implanted to the three patients. The initial dose was 2,4 mcg/die, with increments of 1,2 mcg/die every three days till the maximum dose of 4,8 mcg/die in two patients (survival 61 and 45 days) and 7,2 mcg/die in a pat...

  11. Vapour explosions (fuel-coolant interactions) resulting from the sub-surface injection of water into molten metals: preliminary results

    International Nuclear Information System (INIS)

    Preliminary experiments are reported on the relationship between the injection mode of contact and the occurrence and magnitude of vapour explosions. Water was injected beneath the surface of molten metals, chiefly tin at 250 to 9000C. Vapour explosions occurred in many, but not all, cases. The results are compared with Dullforce's observations (Culham Report (CLM-P424) on the dropping mode of contact and it appears that rather different behaviour is found; in particular, the present results suggest that the Temperature Interaction Zone is different for the two modes of contact. (author)

  12. Preliminary results of natural radioactivity measurements in the southern part of Ethiopia

    Energy Technology Data Exchange (ETDEWEB)

    Wollel Tiruneh, Getachew [Ethiopian Radiation Protection Authority, PO Box 20486 code 1000, Addis-Ababa (Ethiopia)], E-mail: gwollel@yahoo.com; Wodaje Kebede, Worku [Ethiopian Radiation Protection Authority, PO Box 20486 code 1000, Addis-Ababa (Ethiopia)

    2008-11-15

    The paper presents the first results of natural radioactivity measurements in the Southern part of Ethiopia (Bale Zone-Oromiya Regional State). The preliminary results indicate that radiation levels in the mining areas of Kallido Mountain are elevated compared with those in the town of Negele Borena (background area). Both external gamma radiation and alpha surface contamination levels are significantly elevated above local background levels.

  13. Preliminary results of natural radioactivity measurements in the southern part of Ethiopia

    International Nuclear Information System (INIS)

    The paper presents the first results of natural radioactivity measurements in the Southern part of Ethiopia (Bale Zone-Oromiya Regional State). The preliminary results indicate that radiation levels in the mining areas of Kallido Mountain are elevated compared with those in the town of Negele Borena (background area). Both external gamma radiation and alpha surface contamination levels are significantly elevated above local background levels

  14. Mass transport phenomena during solidification in microgravity; preliminary results of the first Mephisto flight experiment

    Science.gov (United States)

    Favier, J. J.; Garandet, J. P.; Rouzaud, A.; Camel, D.

    1994-06-01

    The MEPHISTO space facility flew on the Columbia space shuttle in October 1992. The preliminary scientific results, mainly based on the analysis of the Seebeck signal, are presented in this paper. Valuable information was obtained for both planar and cellular solidification regimes. It is shown that mass transfer in the melt during the flight was principally diffusive; however, even in microgravity, slow growth rates may result in significant convective transport. A tentative interpretation of the Seebeck signal for destabilized interfaces is also proposed.

  15. Imaging screening of breast cancer: primary results in 5307 cases

    International Nuclear Information System (INIS)

    Objective: To discuss the values of three screening methods for the detection of early breast cancer, and to analyze the features of the screening cancer. Methods: The first screening of breast cancer were performed in 5307 women who aged from 20 to 76 years with median age of 49 years. The three screening methods included physical examination with ultrasound and mammography, physical examination with mammography and mammography only. The rate of recall, biopsy, cancer detection of three methods were analyzed and the mammographic findings were reviewed. Chi-square test or Fisher's exact test were used for the statistics. Results: The recall rates were 4.90% (49/1001), 6.90% (166/2407) and 4. 48% (85/1899) in three methods respectively, the biopsy rates were 1.60% (16/1001), 1.04% (25/2407) and 0.63% (12/1899), the cancer detection rates were 0.50% (5/1001), 0.17% (4/2407) and 0 (0/1899). There were statistical differences among the three groups (χ2=12.99,6.264,8.764, P<0.05). Physical examination with ultrasound and mammography had the highest cancer detection rate, ten breast cancers were detected and 8 were early stage breast cancer. Of seven cancers detected by mammography, only two were found by ultrasound. A cluster of calcifications were found in 2 cases, linear calcifications in 2 cases. One case presented as a asymmetric density, one as a asymmetric density with calcifications, one as multiple nodules with a cluster of calcifications. Two breast cancers presented as asymmetric density were missed on mammography and diagnosed correctly after retrospective review. Conclusion: Physical examination with ultrasound and mammography is the best method for breast cancer screening. The breast cancer can be detected by mammography earlier than other methods. (authors)

  16. Prone breast radiotherapy in early-stage breast cancer: a preliminary analysis

    International Nuclear Information System (INIS)

    Purpose: Women with large breasts have marked dose inhomogeneity and often an inferior cosmetic outcome when treated with breast conservation compared to smaller-sized patients. We designed a prone breast board, which both minimizes breast separation and irradiated lung or heart volume. We report feasibility, cosmesis, and preliminary local control and survival for selected women with Stage 0-II breast cancer. Materials and Methods: Fifty-six patients with clinical Stage 0-II breast cancer were treated with lumpectomy and breast irradiation utilizing a prototype prone breast board. A total of 59 breasts were treated. Indications for treatment in the prone position were large or pendulous breast size (n = 57), or a history of cardiopulmonary disease (n = 2). The median bra size was 41D (range, 34D-44EE). Cosmesis was evaluated on a 1-10 (worst-to-best) scale. Results: Acute toxicity included skin erythema (80% of patients experienced Grade I or Grade II erythema), breast edema (72% of patients experienced mild edema), pruritus (20% of patients), and fatigue (20% of patients reported mild fatigue). One patient required a treatment break. The only late toxicity was related to long-term cosmesis. The mean overall cosmesis score for 53 patients was 9.37 (range, 8-10). Actuarial 3- and 5-year local control rates are 98%. Actuarial overall survival at 3 and 5 years are 98% and 94%. Conclusion: Our data indicate that treating selected women with prone breast radiotherapy is feasible and tolerated. The approach results in excellent cosmesis, and short-term outcome is comparable to traditional treatment techniques. This technique offers an innovative alternative to women who might not otherwise be considered candidates for breast conservation

  17. Ziconotide in severe, drug-resistant cancer pain. preliminary experience

    Directory of Open Access Journals (Sweden)

    Angelo Lavano

    2008-12-01

    Full Text Available The Author reports the case of ziconotide intrathecal treatment in three terminal cancer patients, with nociceptive and neuropathic pain, unresponsive to the treatment with intrathecal opioid and adjuvant drugs. An external pump for continuous subarachnoid infusion was implanted to the three patients. The initial dose was 2,4 mcg/die, with increments of 1,2 mcg/die every three days till the maximum dose of 4,8 mcg/die in two patients (survival 61 and 45 days and 7,2 mcg/die in a patient (survival 52 days. VAS reduction was 50% in the fi rst patient, of 57% in the second one and 70% in the third one. In one case, at the dose of 4,8 mcg/die, the treatment was associated with important collateral effects, that requested the temporary suspension of the drug.

  18. Preliminary experimental results on studying possibility of variable mass liner (VML) formation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    The main objective of the present experiment was to study the formation process and initial stage of acceleration of a variable-mass plasma liner (VML). The method is based on magnetic acceleration of a liner with the mass reduced during such acceleration. The experiment was carried out on February 16 at VNIIEF. This report describes the results of measurements obtained in the experiment and preliminary analysis of the results characterizing operation of the test facility main units: helical EMG; 5-module disk EMG 400 mm in diameter (DEMG); ponderomotive unit (PU) with a cylindric condensed liner and a special tooth-cutoff. The first part of the report presents measurement results obtained on the VNIIEF`s diagnostic equipment that are compared with those obtained by American specialists on their diagnostic equipment. Information submitted by American specialists is included in part 2 of this report. The second part of the report presents preliminary computational-theoretic analysis of the main measured results describing operation of DEMG TL system in the experiment; experimental data are compared with theoretical ones obtained before and after the experiment. But more emphasis is placed on the data preliminary analysis indicating that in the experiment a variable mass liner is formed (VML or plasma bubble).

  19. Preliminary experimental results on studying possibility of variable mass liner (VML) formation

    International Nuclear Information System (INIS)

    The main objective of the present experiment was to study the formation process and initial stage of acceleration of a variable-mass plasma liner (VML). The method is based on magnetic acceleration of a liner with the mass reduced during such acceleration. The experiment was carried out on February 16 at VNIIEF. This report describes the results of measurements obtained in the experiment and preliminary analysis of the results characterizing operation of the test facility main units: helical EMG; 5-module disk EMG 400 mm in diameter (DEMG); ponderomotive unit (PU) with a cylindric condensed liner and a special tooth-cutoff. The first part of the report presents measurement results obtained on the VNIIEF's diagnostic equipment that are compared with those obtained by American specialists on their diagnostic equipment. Information submitted by American specialists is included in part 2 of this report. The second part of the report presents preliminary computational-theoretic analysis of the main measured results describing operation of DEMG TL system in the experiment; experimental data are compared with theoretical ones obtained before and after the experiment. But more emphasis is placed on the data preliminary analysis indicating that in the experiment a variable mass liner is formed (VML or plasma bubble)

  20. Results and analysis of screening for breast cancer

    International Nuclear Information System (INIS)

    Breast cancer is the most frequent cause of death in most countries of the world. Screening of asymptomatic women can detect a large percentage of cancers at an early stage. This is the basis for a possible cure or at least a prolongation of the survival time. The percentage of minimal cancers (smaller than 1 cm without dissemination) may be as high as 48% depending on the screening modality (10% without screening), axillary lymph node involvement can be reduced to 20% (40% without screening), and the percentage of stage II to IV cancers can be reduced to 8-20% (60% without screening). Mortality in the study group over age 50 years was reduced by 30%. Disadvantages of screening are: high cost; biopsies prompted by false positive results; psychological stress for the patients; radiation hazards which have, however, become almost negligible thanks to improved technique (2 cancers in 1 million mammographies and year). (Author)

  1. Understanding the Health Behaviors of Survivors of Childhood and Young-Adult Cancer: Preliminary Analysis and Model Development

    Directory of Open Access Journals (Sweden)

    Stefanie C. Vuotto

    2015-05-01

    Full Text Available The current study presents preliminary correlational data used to develop a model depicting the psychosocial pathways that lead to the health behaviors of survivors of childhood and young-adult cancer. Data collected from a sample of 18- to 30-year-old cancer survivors (n = 125 was used to examine the relations among interpersonal support and nonsupport, personal agency, avoidance, depressive symptoms and self-efficacy as they related to health behaviors. The outcome measures examined included tobacco and alcohol use, diet, exercise, sunscreen use, medication compliance and follow-up/screening practices. Correlational analyses revealed a number of significant associations among variables. Results are used to inform the development of a health behavior model. Implications for health promotion and survivorship programming are discussed, as well as directions for future research.

  2. Preliminary Results of the Echo-Seeding Experiment ECHO-7 at SLAC

    Energy Technology Data Exchange (ETDEWEB)

    Xiang, D.; Colby, E.; Ding, Y.; Dunning, M.; Frederico, J.; Gilevich, S.; Hast, C.; Jobe, K.; McCormick, D.; Nelson, J.; Raubenheimer, T.O.; Soong, K.; Stupakov, G.; Szalata, Z.; Walz, D.; Weathersby, S.; Woodley, M.; /SLAC; Corlett, J.; Qiang, J.; Penn, G.; Prestemon, S.; /LBL, Berkeley /LPHE, Lausanne

    2010-06-15

    ECHO-7 is a proof-of-principle echo-enabled harmonic generation FEL experiment in the Next Linear Collider Test Accelerator (NLCTA) at SLAC. The experiment aims to generate coherent radiation at 318 nm and 227 nm, which are the 5th and 7th harmonic of the infrared seed laser. In this paper we present the preliminary results from the commissioning run of the completed experimental setup which started in April 2010.

  3. Neolithic plant use in the western Mediterranean region: preliminary results from the AGRIWESTMED Project

    OpenAIRE

    Peña-Chocarro, Leonor; Pérez Jordá, Guillem; Morales Mateos, Jacob; Zapata, Lydia

    2013-01-01

    This contribution focuses on the preliminary results of the AGRIWESTMED project which focuses on the archaeobotanical analyses of early Neolithic sites in the western Mediterranean region (both in Iberia and in northern Morocco). A large number of sites has been studied producing an interesting dataset of plant remains which places the earliest examples of domesticated plants in the second half of the 6th millennium cal BC. Plant diversity is high as it is shown by the large number o...

  4. DETECTION OF Helicobacter pylori IN GASTRIC MUCOSA OF SHEEP: PRELIMINARY RESULTS

    OpenAIRE

    A. Rella; C. Tamborrino; G. V. Celano; Normanno, G; Alberti, F.; A. Dambrosio; N.C. Quaglia

    2013-01-01

    Helicobacter pylori is an organism widespread in humans and sometimes responsible for serious illnesses. It has been hypothesized the existence of animal reservoirs, and that the infection route by H. pylori involves multiple pathways including food-borne transmission as the microorganism has been detected from sheep, goat and cow milk. This work reports the preliminary results of a survey conducted in order to investigate the presence of H. pylori in gastric mucosa of sheep slaughtered in Ap...

  5. Parallel Guided Local Search and Some Preliminary Experimental Results for Continuous Optimization

    Directory of Open Access Journals (Sweden)

    Nasser Tairan

    2014-02-01

    Full Text Available This paper proposes a Parallel Guided Local Search (PGLS framework for continuous optimization. In PGLS, several guided local search (GLS procedures (agents are run for solving the optimization problem. The agents exchan ge information for speeding up the search. For example, the information exchanged could be kno wledge about the landscape obtained by the agents. The proposed algorithm is applied to co ntinuous optimization problems. The preliminary experimental results show that the algo rithm is very promising .

  6. Investigation of polarized-proton target materials by differential calorimetry: preliminary results

    International Nuclear Information System (INIS)

    A simple differential calorimeter was designed and operated for an investigation of the thermodynamic properties of polarized target materials. The calibration and use of the calorimeter are discussed, after a brief exposition of our motivation for this work. The results of a preliminary study of target materials is presented with emphasis on the relevance of the glass state to dynamic polarization in chemically-doped targets

  7. First steps of laparoscopic surgery in Lubumbashi: problems encountered and preliminary results

    OpenAIRE

    Arung, Willy; Dinganga, Nathalie; Ngoie, Emmanuel; Odimba, Etienne; Detry, Olivier

    2015-01-01

    For many reasons, laparoscopic surgery has been performed worldwide. Due to logistical constraints its first steps occurred in Lubumbashi only in 2008. The aim of this presentation was to report authors’ ten-month experience of laparoscopic surgery at Lubumbashi Don Bosco Missionary Hospital (LDBMH): problems encountered and preliminary results. The study was a transsectional descriptive work with a convenient sampling. It only took in account patients with abdominal surgical condition who co...

  8. The RPC-based IFR system at BaBar experiment preliminary results

    CERN Document Server

    Piccolo, D; Bagnasco, S; Baldini, R; Band, H R; Bionta, R; Buzzo, A; Calcaterra, A; Cavallo, N; Contri, R; Crosetti, G; De Nardo, Gallieno; De Sangro, R; Fabozzi, F; Falciai, D; Finocchiaro, G; Gatto, C; Johnson, J; Lista, L; Lo Vetere, M; Macri, M; Monge, R; Palano, A; Paolucci, P; Passaggio, S; Patrignani, C; Patteri, P; Peruzzi, I; Piccolo, M; Robutti, E; Santroni, A; Sciacca, C; Wright, D; Yu, Z; Zallo, A

    2002-01-01

    The IFR system is a RPC-based detector used to identify muons and neutral hadrons in the BaBar experiment at PEP II machine in SLAC. The RPC system can be used to reconstruct the trajectory of muons, pions and neutral hadrons interacting in the iron of the IFR. The different range and hit pattern allow to discriminate different particles crossing the IFR. An overview of the system design and the preliminary results on the IFR performances are reported.

  9. Facial emotional recognition in schizophrenia: preliminary results of the virtual reality program for facial emotional recognition

    OpenAIRE

    Teresa Souto; Alexandre Baptista; Diana Tavares; Cristina Queirós; Marques António

    2013-01-01

    BACKGROUND: Significant deficits in emotional recognition and social perception characterize patients with schizophrenia and have direct negative impact both in inter-personal relationships and in social functioning. Virtual reality, as a methodological resource, might have a high potential for assessment and training skills in people suffering from mental illness. OBJECTIVES: To present preliminary results of a facial emotional recognition assessment designed for patients with schizophrenia,...

  10. Holocene evolution and sedimentation rate of Alikes Lagoon, Zakynthos island, Western Greece – preliminary results

    OpenAIRE

    P. Avramidis; N. Kontopoulos

    2009-01-01

    In the present study we present preliminary results of Zakynthos Alikes lagoon, which is one of the most seismically active regions of Greece. In order to estimate – interpret the Holocene evolution of the area and to reconstruct the palaeonvironmental changes, we based on the data of a 21 m sediment core. Sediment types, structure, colour, as well as contact depths and bed characteristics, were recorded in the field. Standarised sedimentological analysis were carried out, on 46 samples inclu...

  11. The evaluation of GL impact in Physical sciences using bibliometric indicators : preliminary results

    OpenAIRE

    Di Cesare, Rosa; GreyNet, Grey Literature Network Service

    1994-01-01

    A bibliometric study of the Italian grey literature in SIGLE database. Preliminary results. Given the increasing importance of Grey Literature (GL) for the information and documentation field, it is essential to apply a bibliometric analysis similar to the one widely used for the conventional literature. Study objectives: 1) impact evalutation of grey literature in physical sciences; and 2) differentiation between scientific and non scientific grey literature documents in the same discipline,...

  12. Nucleon resonance decay by the $K^{0} \\sum^{+}$ channel: Preliminary results

    Indian Academy of Sciences (India)

    S V Shende; R Castelijns; J C S Bacelar; H Löhner; J Messchendorp; CBELSA/TAPS Collaboration

    2006-05-01

    The strange meson production on a proton target in the $K^{0} \\sum^{+}$ channel is sensitive to nucleon resonance contributions. The $K^{0}$ production on a deuteron target can provide information on the hyperon-nucleon final-state interaction. The experiments $ p → K^{0} \\sum^{+}$ and $ d → K^{0} \\sum^{+} n$ have been carried out at the ELSA facility at Bonn. In this paper, we report the preliminary results of both experiments.

  13. Preliminary results and analyses of using IGS GPS data to determine global ionospheric TEC

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Using the spherical harmonic (SH) function model and the dual frequency GPS data of 139 International GPS Service (IGS) stations for July 15 of 2000, the global ionospheric total electron content (TEC) is calculated and the basic method is investigated. Here, preliminary results are reported and the problems and difficulties to be solved for using GPS data to determine the global ionospheric TEC are discussed.

  14. Preliminary results from a passive seismic array over the Chicxulub impact structure in Mexico

    OpenAIRE

    P. K. H. Maguire; Mackenzie, G D; Denton, P.; Trejo, A.; Rainer Kind

    1998-01-01

    A passive, 20-element, short-period (1 Hz) and broadband seismic array was deployed over the Chicxulub impact structure for c. 100 days in early 1996. The principal objective was to study the shear-wave anisotropy associated with the structure; in particular, to determine the presence (or absence= of radial symmetry which will allow comment on the time variance of that anisotropy. A total of 15 teleseismic, 75 regional, and 100 local events were recorded. Preliminary results from studies of t...

  15. Usefulness of Integrated PET/MRI in Head and Neck Cancer: A Preliminary Study

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Soo Jin; Seo, Hyo Jung; Cheon, Gi Jeong; Kim, Ji Hoon; Kim, E. Edmund; Kang, Keon Wook; Paeng, Jin Chul; Chung, Junekey; Lee, Dong Soo [Seoul National Univ., Seoul (Korea, Republic of)

    2014-06-15

    -body positron emission tomography (PET) only, dedicated MR, regional positron emission tomography (PET) only and regional PET/Gd-MRI, respectively. There was no distant metastasis based on analysis of whole-body positron emission tomography (PET) and whole-body PET/Dixon-volume interpolated breathhold examination (VIBE) MRI. Regional PET/Gd-MRI combined with whole-body PET/MRI modified staging in three patients. Lesions of primary tumor and suspicious metastasis were well detected on both value of SUVmax and visual analysis. The regional PET/Gd-MRI combined with whole-body PET/MRI showed convenient clinical staging performance compared with positron emission tomography (PET) and MRI alone. In this preliminary study, PET attenuated by MRI showed good image quality to detect lesions. And whole-body PET/MRI as a single modality was feasible for staging in a clinical setting. Whole-body positron emission tomography (PET), regional positron emission tomography (PET), dedicated MRI and regional PET/Gd-MRI showed discordant results in lesion detection. These discordant results might be synergistic effect for accurate staging.

  16. Most significant preliminary results of the probabilistic safety analysis on the Juragua nuclear power plant

    International Nuclear Information System (INIS)

    Since 1990 the Group for PSA Development and Applications (GDA/APS) is working on the Level-1 PSA for the Juragua-1 NPP, as a part of an IAEA Technical Assistance Project. The main objective of this study, which is still under way, is to assess, in a preliminary way, the Reactor design safety to find its potential 'weak points' at the construction stage, using a eneric data base. At the same time, the study allows the PSA team to familiarize with the plant design and analysis techniques for the future operational PSA of the plant. This paper presents the most significant preliminary results of the study, which reveal some advantages of the safety characteristics of the plant design in comparison with the homologous VVER-440 reactors and some areas, where including slight modifications would improve the plant safety, considering the level of detail at which the study is carried out. (author). 13 refs, 1 fig, 2 tabs

  17. Preliminary mixed-layer model results for FIRE marine stratocumulus IFO conditions

    Science.gov (United States)

    Barlow, R.; Nicholls, S.

    1990-01-01

    Some preliminary results from the Turton and Nicholls mixed layer model using typical FIRE boundary conditions are presented. The model includes entrainment and drizzle parametrizations as well as interactive long and shortwave radiation schemes. A constraint on the integrated turbulent kinetic energy balance ensures that the model remains energetically consistent at all times. The preliminary runs were used to identify the potentially important terms in the heat and moisture budgets of the cloud layer, and to assess the anticipated diurnal variability. These are compared with typical observations from the C130. Sensitivity studies also revealed the remarkable stability of these cloud sheets: a number of negative feedback mechanisms appear to operate to maintain the cloud over an extended time period. These are also discussed. The degree to which such a modelling approach can be used to explain observed features, the specification of boundary conditions and problems of interpretation in non-horizontally uniform conditions is also raised.

  18. Yoga for Persistent Fatigue in Breast Cancer Survivors: Results of a Pilot Study

    Directory of Open Access Journals (Sweden)

    Julienne E. Bower

    2011-01-01

    Full Text Available Approximately one-third of breast cancer survivors experiences persistent fatigue for months or years after successful treatment completion. There is a lack of evidence-based treatments for cancer-related fatigue, particularly among cancer survivors. This single-arm pilot study evaluated the feasibility and preliminary efficacy of a yoga intervention for fatigued breast cancer survivors based on the Iyengar tradition. Iyengar yoga prescribes specific poses for individuals with specific medical problems and conditions; this trial emphasized postures believed to be effective for reducing fatigue among breast cancer survivors, including inversions and backbends performed with the support of props. Twelve women were enrolled in the trial, and 11 completed the full 12-week course of treatment. There was a significant improvement in fatigue scores from pre- to post-intervention that was maintained at the 3-month post-intervention followup. Significant improvements were also observed in measures of physical function, depressed mood, and quality of life. These results support the acceptability of this intervention and suggest that it may have beneficial effects on persistent post-treatment fatigue. However, results require replication in a larger randomized controlled trial.

  19. Physical activity in solid organ transplant recipients: organizational aspects and preliminary results of the Italian project.

    Science.gov (United States)

    Roi, G S; Stefoni, S; Mosconi, G; Brugin, E; Burra, P; Ermolao, A; Granito, M; Macini, P; Mastrosimone, S; Nacchia, F; Pegoraro, C; Rigotti, P; Sella, G; Sgarzi, S; Tamè, M R; Totti, V; Trerotola, M; Tripi, F; Nanni Costa, A

    2014-09-01

    Most of the difficulties when trying to realize the proposal to prescribe physical activity for transplantation patients come from patient attitudes and cultural beliefs that ignore the benefits of exercise, but there also are organizational aspects arising from the difficulties that these patients face in accessing supervised exercise facilities. To address these difficulties, the Italian study project "Transplant … and Now Sport" was developed based on a model of cooperation among transplantation specialists, sports physicians, and exercise specialists organized as a team combining their specific skills to effectively actuate the physical exercise programs. This preliminary report is based on 26 patients (16 male, 10 female; 47.8±10.0 years old; 21 kidney and 5 liver transplantations; time from transplantation 2.3±1.4 years) who performed prescribed and supervised exercises consisting of 3 sessions per week of aerobic and strengthening exercises for 1 year. Preliminary results show a significant decrease in body mass index (t=1.966; PSocial Functioning, and Role Emotional scale scores showed a significant improvement (P<.05). Preliminary results of the study protocol "Transplant…and Now Sport" show the positive effects of the model based on cooperation among transplantation centers, sports medicine centers, and gyms in the administration of a supervised exercise prescription. These data should be considered a contribution to developing and promoting further detailed exercise protocols and to fostering improved posttransplantation health and survival, helping to ensure that physical activity becomes a safe routine medical treatment plan of patient management.

  20. Is prostate cancer screening responsible for the negative results of prostate cancer treatment trials?

    Science.gov (United States)

    Prasad, Vinay

    2016-08-01

    Clinical guidelines continue to move away from routine prostate specific antigen screening (PSA), once a widespread medical practice. A curious difference exists between early prostate cancer and early breast cancer. While randomized trials of therapy in early breast cancer continue to show overall survival benefit, this is not the case in prostate cancer, where prostatectomy was no better than observation in a recent trial, and where early androgen deprivation is no better than late androgen deprivation. Here, I make the case that prostate cancer screening contributes so greatly to over diagnosis that even treatment trials yield null results due to contamination with non-life threatening disease. PMID:27372859

  1. 77 FR 12008 - Certain Pasta From Italy: Extension of Time Limit for the Preliminary Results of Antidumping Duty...

    Science.gov (United States)

    2012-02-28

    ... Request for Revocation in Part, 76 FR 53404 (August 26, 2011). The preliminary results of this review are... International Trade Administration Certain Pasta From Italy: Extension of Time Limit for the Preliminary Results... administrative review of the antidumping duty order on certain pasta from Italy, covering the period July 1,...

  2. 76 FR 6604 - Certain Pasta From Italy: Extension of Time Limit for the Preliminary Results of the...

    Science.gov (United States)

    2011-02-07

    ... Initiation of Administrative Review, 75 FR 53274 (August 31, 2010). The preliminary results of this... Act of 1930, as Amended, 70 FR 24533 (May 10, 2005). The final results continue to be due 120 days... International Trade Administration Certain Pasta From Italy: Extension of Time Limit for the Preliminary...

  3. Improving Indigenous access to cancer screening and treatment services: descriptive findings and a preliminary report on the Midwest Indigenous Women’s Cancer Support Group

    Directory of Open Access Journals (Sweden)

    Lisabeth D Finn

    2008-01-01

    Full Text Available BackgroundHigher cancer morbidity and mortality rates for the Indigenous population comparedto the overall Australian population has underlined the critical need to improve accessfor Aboriginal people to cancer treatment services. This paper describes anIndigenous Women’s Cancer Support Group (IWCSG established to supportIndigenous people with cancer and their carers/relatives and to facilitate Aboriginalaccess to cancer screening and treatment. Preliminary findings from an evaluation ofthe group are presented.MethodsThe study employed qualitative research methods to describe IWCSG operations andinvestigate the group’s effectiveness. It included one-on-one interviews with 11Geraldton-based health service providers, the IWCSG coordinator, and 10 womenwho have been linked to IWCSG support, as well as observation of group meetings.ResultsDescriptive outcomes relate to group operations, group effectiveness, group benefitsand future development of the group. A cultural strength of IWCSG is its ability tooperate confidentially behind the scenes, providing emotional support and practicalhelp directly to Indigenous people concerned about privacy and shame issues. Theimportant cultural role IWCSG plays in overcoming communication and othercultural barriers to accessing cancer treatment was unanimously recognised by healthservice providers. Aboriginal women supported by IWCSG spoke about an increasedsense of safety, trust and support in accessing and navigating mainstream cancerservices. A critical issue emerging from the research is the need for further development of effective collaborative working relationships between IWCSGmembers and health service providers.ConclusionsThe IWCSG has the potential to inform an effective model for facilitating Indigenousaccess both to cancer treatment and to mainstream treatment for a variety of healthproblems. Future research is required to explore the applicability of Indigenoussupport groups and to focus on the

  4. Preliminary specification of X-ray CT for lung cancer screening (LSCT) and its evaluation on risk-cost-effectiveness

    International Nuclear Information System (INIS)

    In Japan mass screening for lung cancer is widely performed by chest X-ray film of 10 x 10 cm, with sputum cytology for high-risk groups. However, the effectiveness of the present mass screening program for lung cancer has been less than expected, although some data have shown improvement of the survival rate as a result of mass screening. We propose a new X-ray CT method of screening for lung cancer called Lung Cancer Screening CT (LSCT). The preliminary specifications for LSCT are as follows: scan speed is within 10 sec for a 40 cm length with a 1 cm slice thickness, and the absorption dose for lung is less than 1 cGy. A computer-assisted diagnostic system is necessary for image reading. The risk-benefit analysis of LSCT indicates that Japanese men and women over 45 years old can be screened in 1992 and thereafter. The cost per person·year of LSCT screening is estimated to be 1.4 x 106 yen for a population incidence rate of 50 x 10-5 person/year and average life expectancy of 30 years. In 1992 the above condition will be satisfied by men aged 55 years old and above, but not by women of any age. We believe that LSCT should be developed further and tested in the high-risk group of men with an incidence rate of 100 x 10-5 person/year or more. (author)

  5. Radon and radon daughters' concentration in spring and wells waters from Presidente Prudente: preliminary results

    International Nuclear Information System (INIS)

    This work presents the preliminary results about the concentration of radon and radon daughters in wells and springs water from Presidente Prudente. Six water samples were studied: three from well-water, two from springs water and one from potable water. For the determination of α-activity the samples were placed inside plastic containers where the CR-39 tracks detectors were outside the water. The track density of α-particles were measured by using optical microscopy. The results show that one sample from well-water presented higher concentration of radon and radon daughters than the other samples. (author)

  6. Preliminary Experimental Results for Indirect Vector-Control of Induction Motor Drives with Forced Dynamics

    Directory of Open Access Journals (Sweden)

    Jan Vittek

    2003-01-01

    Full Text Available The contribution presents an extension of indirect vector control of electric drives employing induction motors to 'Forced Dynamic Control'. This method of control offers an accurate realisation of dynamic response profiles, which can be selected by the user. The developed system can be integrated into a drive with a shaft position encoder or a shaft sensoriess drive, in which only the stator currents are measured. The applied stator voltages are determined by a computed inverter switching algorithm. Simulation results and preliminary experimental results for indirect vector control of an idle running induction motor indicate good agreement with the theoretical predictions.

  7. Response of lead-acid batteries to chopper-controlled discharge: Preliminary results

    Science.gov (United States)

    Cataldo, R. L.

    1978-01-01

    The preliminary results of simulated electric vehicle, chopper, speed controller discharge of a battery show energy output losses up to 25 percent compared to constant current discharges at the same average discharge current of 100 amperes. These energy losses are manifested as temperature rises during discharge, amounting to a two-fold increase for a 400-ampere pulse compared to the constant current case. Because of the potentially large energy inefficiency, the results suggest that electric vehicle battery/speed controller interaction must be carefully considered in vehicle design.

  8. Ion currents and energies in reactive low-voltage ion plating: preliminary results

    Science.gov (United States)

    Edlinger, Johannes P.; Pulker, Hans K.

    1990-12-01

    Reactive Low-Voltage Ion Plating (RLVIP) is a plasma-assisted evaporation process that produces anorganic oxide- and nitride films with a closed microstructure. in order to better understand the process and the resulting film properties a BALZERS PPM 400 Plasmamonitor, a combination of a quadrupole mass filter and an energy selective ion optics, has been used to study the relative abundancies and energy distributions of the ions impinging on the growing film in the RLVIP process. The device is discussed and preliminary results are presented: The plasma is anisotropic. Surprisingly it contains ions with higher energies than expected from the self-bias potential.

  9. Clinical management of gastric cancer: results of a multicentre survey

    Directory of Open Access Journals (Sweden)

    Xu Feng

    2011-08-01

    Full Text Available Abstract Background The National Comprehensive Cancer Network clinical practice guidelines in oncology-gastric cancer guidelines have been widely used to provide appropriate recommendations for the treatment of patients with gastric cancer. The aim of this study was to examine the adherence of surgical oncologists, medical oncologists, and radiation oncologists' to the recommended guidelines. Methods A questionnaire asking the treatment options for gastric cancer cases was sent to 394 Chinese oncology specialists, including surgical oncologists, medical oncologists, and radiation oncologists working in hospitals joined in The Western Cooperative Gastrointestinal Oncology Group of China. The questionnaire involved a series of clinical scenarios regarding the interpretation of surgery, neoadjuvant, adjuvant, and advanced treatment planning of gastric cancer. Results Analysis of 358 respondents (91% showed variations between each specialization and from the recommended guidelines in the management approaches to specific clinical scenarios. The majority of specialists admitted that less than 50% of patients received multidisciplinary evaluation before treatment. The participants gave different responses to questions involving adjuvant, neoadjuvant, and advanced settings, compared to the recommended guidelines. Conclusions These results highlight the heterogeneity of the treatment of gastric cancer. Surgical oncologists, medical oncologists, and radiation oncologists are not adhering to the recommended guidelines.

  10. 77 FR 15718 - Certain Pasta from Italy: Extension of Time Limit for the Preliminary Results of the...

    Science.gov (United States)

    2012-03-16

    ... Revocation in Part, 76 FR 53404 (August 26, 2011). The preliminary results of this administrative review are... Act of 1930, As Amended, 70 FR 24533 (May 10, 2005). Statutory Time Limits Section 751(a)(3)(A) of the... International Trade Administration Certain Pasta from Italy: Extension of Time Limit for the Preliminary...

  11. 77 FR 11485 - Certain Pasta From Turkey: Extension of Time Limit for the Preliminary Results of Antidumping...

    Science.gov (United States)

    2012-02-27

    ... Reviews and Requests for Revocation in Part, 76 FR 53404 (August 26, 2011). The preliminary results of... International Trade Administration Certain Pasta From Turkey: Extension of Time Limit for the Preliminary... administrative review of the antidumping duty order on certain pasta from Turkey, covering the period July...

  12. p53 Response to Ultrasound: Preliminary Observations in MCF7 Human Breast Cancer Cells

    Science.gov (United States)

    Burns, Janis M.; Campbell, Paul A.

    2011-09-01

    Mutated p53 can be found in approximately half of all human cancers. Strategies which seek to restore, or at least exercise a level of external control over, p53 functionality are thus potentially useful as adjuncts to therapy. Here, we report our preliminary measurements in this area, and demonstrate that short-burst pulsed ultrasound can indeed affect p53 activity. Specifically, we have observed that expression of the p53 protein can be regulated in the period immediately following low intensity short pulse (millisecond) ultrasound exposure, and that altered activity levels return to basal levels over a 24 hour period post-insonation.

  13. Cancer Incidence in Egypt: Results of the National Population-Based Cancer Registry Program

    OpenAIRE

    Amal S. Ibrahim; Khaled, Hussein M.; Nabiel NH Mikhail; Hoda Baraka; Hossam Kamel

    2014-01-01

    Background. This paper aims to present cancer incidence rates at national and regional level of Egypt, based upon results of National Cancer Registry Program (NCRP). Methods. NCRP stratified Egypt into 3 geographical strata: lower, middle, and upper. One governorate represented each region. Abstractors collected data from medical records of cancer centers, national tertiary care institutions, Health Insurance Organization, Government-Subsidized Treatment Program, and death records. Data ...

  14. Preliminary Results of Ion Beam Extraction Tests on EAST Neutral Beam Injector

    Institute of Scientific and Technical Information of China (English)

    胡纯栋

    2012-01-01

    The neutral beam injection (NBI) system is one of the most important auxiliary plasma heating and current driving methods for fusion device. A high power ion beam of 3 MW with 80 keV beam energy in 0.5 s beam duration and a long pulse ion beam of 4 s with 50 keV beam energy ion beam extraction were achieved on the EAST neutral beam injector on the teststand. The preliminary results show that the EAST-NBI system was developed successfully on schedule.

  15. VNIIEF-ORNL Joint Plutonium Measurements with NMIS and Results of Plutonium Attributes Preliminary Evaluations

    International Nuclear Information System (INIS)

    Within the frameworks of TO No.007 between ORNL and VNIIEF on Nuclear Materials Identification System (NMIS) mastering at VNIIEF in July 2000 there had been finalized joint measurements, in which NMIS-technique equipment was used that had been placed at VNIIEF's disposal by ORNL, as well as VNIIEF-produced unclassified samples of fissile materials. In the report there are presented results of experimental data preliminary processing to obtain absolute values of some attributes used in plutonium shells measurements: values of their mass and thickness. Possibility of fissile materials parameters absolute values obtaining from measurement data essentially widens NMIS applicability to the tasks relevant to these materials inspections

  16. Design and preliminary results of a fuel flexible industrial gas turbine combustor

    Science.gov (United States)

    Novick, A. S.; Troth, D. L.; Yacobucci, H. G.

    1981-01-01

    The design characteristics are presented of a fuel tolerant variable geometry staged air combustor using regenerative/convective cooling. The rich/quench/lean variable geometry combustor is designed to achieve low NO(x) emission from fuels containing fuel bound nitrogen. The physical size of the combustor was calculated for a can-annular combustion system with associated operating conditions for the Allison 570-K engine. Preliminary test results indicate that the concept has the potential to meet emission requirements at maximum continuous power operation. However, airflow sealing and improved fuel/air mixing are necessary to meet Department of Energy program goals.

  17. UAS Integration into the NAS: iHTL: DAA Display Evaluation Preliminary Results

    Science.gov (United States)

    Fern, Lisa; Rorie, Conrad; Shively, Jay

    2014-01-01

    The integrated human-in-the-loop (iHITL) simulation examined the effect of four different Detect-and-Avoid (DAA) display concepts on unmanned aircraft system (UAS) pilots' ability to maintain safe separation. The displays varied in the type and amount of guidance they provided to pilots. The study's background and methodology are discussed, followed by a presentation of the preliminary 'measured response' data (i.e., pilots' end-to-end response time in reacting to traffic alerts on their DAA display). Results indicate that display type had moderate to no affect on pilot measured response times.

  18. Preliminary Results from Small-Pixel CdZnTe and CdTe Arrays

    Science.gov (United States)

    Ramsey, B. D.; Sharma, D. P.; Meisner, J.; Austin, R. A.

    1999-01-01

    We have evaluated 2 small-pixel (0.75 mm) Cadmium-Zinc-Telluride arrays, and one Cadmium-Telluride array, all fabricated for MSFC by Metorex (Finland) and Baltic Science Institute (Riga, Latvia). Each array was optimized for operating temperature and collection bias. It was then exposed to Cadmium-109 and Iron-55 laboratory isotopes, to measure the energy resolution for each pixel and was then scanned with a finely-collimated x-ray beam, of width 50 micron, to examine pixel to pixel and inter-pixel charge collections efficiency. Preliminary results from these array tests will be presented.

  19. Preliminary results of Lean method implementation in a pathology lab from Northeastern Brazil

    Directory of Open Access Journals (Sweden)

    Josiane S. Quetz

    2015-02-01

    Full Text Available Oncologic care shows a growing and unmet demand, and requires the search for alternatives that allow the efficient use of limited resources, the building of autonomy, and the endeavour for continuous improvement of processes. In the present work, we present the implementation of Lean philosophy at a pathology laboratory of an oncology hospital. Among the preliminary results, we highlight the redefinition of the dynamics of the staff, and the physical reorganization of the area. Such important changes culminated in an expressive reduction of lead time, even with a significant increase in the monthly load of exams.

  20. Preliminary results of mental workload and task engagement assessment using electroencephalogram in a space suit.

    Science.gov (United States)

    Rabbi, Ahmed F; Zony, Abongwa N; de Leon, Pablo; Fazel-Rezai, Reza

    2012-01-01

    In this paper, we present preliminary results of subject's mental workload and task engagement assessment in an experimental space suit. We have quantified the mental workload and task engagement based on changes in electroencephalogram (EEG). EEG signals were collected from subjects scalp using a commercial wireless EEG device in two experimental conditions - when subjects did not wear space suit (control condition) and when subjects wore space suit. Brain state changes were estimated and compared with the direct responses for different tasks and different conditions. We found that the spacesuit experiment introduced a greater mental workload where subject's stress levels were higher than control experiment.

  1. Mammography-based screening program: preliminary results from a first 2-year round in a Brazilian region using mobile and fixed units

    Directory of Open Access Journals (Sweden)

    Haikel Raphael

    2012-10-01

    Full Text Available Abstract Background Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer deaths among women worldwide. The use of mobile mammography units to offer screening to women living in remote areas is a rational strategy to increase the number of women examined. This study aimed to evaluate results from the first 2 years of a government-organized mammography screening program implemented with a mobile unit (MU and a fixed unit (FU in a rural county in Brazil. The program offered breast cancer screening to women living in Barretos and the surrounding area. Methods Based on epidemiologic data, 54 238 women, aged 40 to 69 years, were eligible for breast cancer screening. The study included women examined from April 1, 2003 to March 31, 2005. The chi-square test and Bonferroni correction analyses were used to evaluate the frequencies of tumors and the importance of clinical parameters and tumor characteristics. Significance was set at p Results Overall, 17 964 women underwent mammography. This represented 33.1% of eligible women in the area. A mean of 18.6 and 26.3 women per day were examined in the FU and MU, respectively. Seventy six patients were diagnosed with breast cancer (41 (54% in the MU. This represented 4.2 cases of breast cancer per 1000 examinations. The number of cancers detected was significantly higher in women aged 60 to 69 years than in those aged 50 to 59 years (p Conclusions Preliminary results indicate that this mammography screening program is feasible for implementation in a rural Brazilian territory and favor program continuation.

  2. Preliminary results in large bone segmentation from 3D freehand ultrasound

    Science.gov (United States)

    Fanti, Zian; Torres, Fabian; Arámbula Cosío, Fernando

    2013-11-01

    Computer Assisted Orthopedic Surgery (CAOS) requires a correct registration between the patient in the operating room and the virtual models representing the patient in the computer. In order to increase the precision and accuracy of the registration a set of new techniques that eliminated the need to use fiducial markers have been developed. The majority of these newly developed registration systems are based on costly intraoperative imaging systems like Computed Tomography (CT scan) or Magnetic resonance imaging (MRI). An alternative to these methods is the use of an Ultrasound (US) imaging system for the implementation of a more cost efficient intraoperative registration solution. In order to develop the registration solution with the US imaging system, the bone surface is segmented in both preoperative and intraoperative images, and the registration is done using the acquire surface. In this paper, we present the a preliminary results of a new approach to segment bone surface from ultrasound volumes acquired by means 3D freehand ultrasound. The method is based on the enhancement of the voxels that belongs to surface and its posterior segmentation. The enhancement process is based on the information provided by eigenanalisis of the multiscale 3D Hessian matrix. The preliminary results shows that from the enhance volume the final bone surfaces can be extracted using a singular value thresholding.

  3. Nuclear Reactor Component Code CUPID-I: Numerical Scheme and Preliminary Assessment Results

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Hyoung Kyu; Jeong, Jae Jun; Park, Ik Kyu; Kim, Jong Tae; Yoon, Han Young

    2007-12-15

    A component scale thermal hydraulic analysis code, CUPID (Component Unstructured Program for Interfacial Dynamics), is being developed for the analysis of components of a nuclear reactor, such as reactor vessel, steam generator, containment, etc. It adopted three-dimensional, transient, two phase and three-field model. In order to develop the numerical schemes for the three-field model, various numerical schemes have been examined including the SMAC, semi-implicit ICE, SIMPLE, Row Scheme and so on. Among them, the ICE scheme for the three-field model was presented in the present report. The CUPID code is utilizing unstructured mesh for the simulation of complicated geometries of the nuclear reactor components. The conventional ICE scheme that was applied to RELAP5 and COBRA-TF, therefore, were modified for the application to the unstructured mesh. Preliminary calculations for the unstructured semi-implicit ICE scheme have been conducted for a verification of the numerical method from a qualitative point of view. The preliminary calculation results showed that the present numerical scheme is robust and efficient for the prediction of phase changes and flow transitions due to a boiling and a flashing. These calculation results also showed the strong coupling between the pressure and void fraction changes. Thus, it is believed that the semi-implicit ICE scheme can be utilized for transient two-phase flows in a component of a nuclear reactor.

  4. Preliminary assessment of fluorine-18 fluorodeoxyglucose positron emission tomography in patients with bladder cancer

    International Nuclear Information System (INIS)

    The purpose of this study was to assess the feasibility of imaging of bladder cancer with fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) scanning. We studied 12 patients with histologically proven bladder cancer who had undergone surgical procedures and/or radiotherapy. Retrograde irrigation of the urinary bladder with 1000-3710 ml saline was performed during nine of the studies. Dynamic and static PET images were obtained, and standardized uptake value images were reconstructed. FDG-PET scanning was true-positive in eight patients (66.7%), but false-negative in four (33.3%). Of 20 organs with tumor mass lesions confirmed pathologically or clinically, 16 (80%) were detected by FDG-PET scanning. FDG-PET scanning detected all of 17 distant metastatic lesions and two of three proven regional lymph node metastases. FDG-PET was also capable of differentiating viable recurrent bladder cancer from radiation-induced alterations in two patients. In conclusion, these preliminary data indicate the feasibility of FDG-PET imaging in patients with bladder cancer, although a major remaining pitfall is intense FDG accumulation in the urine. (orig.). With 3 figs., 1 tab

  5. Potential usefulness of CTC detection in follow up of prostate cancer patients. A preliminary report obtained by using Adnagene platform

    Directory of Open Access Journals (Sweden)

    Giuseppe Albino

    2013-12-01

    Full Text Available Objective: Prostate cancer (PCa represents one of the most important medical problems for males, being the second major cause of cancer death. Routinely, PCa patients are followed up with both periodic evaluation of serum PSA levels and imaging. Recently, alternative laboratory methods were proposed for PCa patients’ monitoring, with contrasting results. Aim of the present study was to evaluate the usefulness of a new commercially CE-IVD kit for detection of prostate circulating tumour cells. Our intention was to verify the Adnagene platform usefulness to identify patients with disease progression, whatever treatment ongoing, in order to modify the therapeutic process even before treatment failure is evident with imaging methods. Materials and Methods: Twenty-one patients were enrolled and subdivided into three groups: n = 10 high risk tumor PCa patients; n = 6 low risk PCa patients; n = 5 sbjects without any signs of PCa. AdnaTest Prostate Cancer kit was used for enrichment and molecular characterization of prostate circulating tumour cells. Results: Healthy subjects (with BPH and patients without metastases resulted as negative, while 3 out of 10 high risk PCa patients were positive at least for one molecular marker like PSA, while only two showed positivity for PSMA mRNA. Our results indicate that the test specificity is 100% and the sensitivity is 100%; of course the sample is too small to give it statistical validity. In detail we verified that only the “not responder” patients resulted positive for AdnaTest. Conclusions: The present preliminary report provides evidence that isolation and detection of circulating tumour cells (CTCs is feasible and it may be useful in the follow-up of patients with advanced prostate cancer. If the results of this preliminary study would be confirmed by a large prospective cohort study, it could be demonstrated that this test is a rapid diagnostic method, based on the analysis of a blood sample and

  6. DETECTION OF Helicobacter pylori IN GASTRIC MUCOSA OF SHEEP: PRELIMINARY RESULTS

    Directory of Open Access Journals (Sweden)

    A. Rella

    2013-02-01

    Full Text Available Helicobacter pylori is an organism widespread in humans and sometimes responsible for serious illnesses. It has been hypothesized the existence of animal reservoirs, and that the infection route by H. pylori involves multiple pathways including food-borne transmission as the microorganism has been detected from sheep, goat and cow milk. This work reports the preliminary results of a survey conducted in order to investigate the presence of H. pylori in gastric mucosa of sheep slaughtered in Apulia region (Italy employing a Nested Polymerase Chain Reaction (Nested-PCR assay for the detection of the phosphoglucosamine mutase gene (glmM, as screening method followed by conventional bacteriological isolation. Out of the 50 gastric mucosa samples examined, 3 (6% resulted positive for the presence of glmMgene, but at this time no strains were isolated. The results deserve further investigations to asses the role of ruminants as possible reservoirs of H. pylori.

  7. Environmental scan of anal cancer screening practices: worldwide survey results

    International Nuclear Information System (INIS)

    Anal squamous cell carcinoma is rare in the general population but certain populations, such as persons with HIV, are at increased risk. High-risk populations can be screened for anal cancer using strategies similar to those used for cervical cancer. However, little is known about the use of such screening practices across jurisdictions. Data were collected using an online survey. Health care professionals currently providing anal cancer screening services were invited to complete the survey via email and/or fax. Information was collected on populations screened, services and treatments offered, and personnel. Over 300 invitations were sent; 82 providers from 80 clinics around the world completed the survey. Fourteen clinics have each examined more than 1000 patients. Over a third of clinics do not restrict access to screening; in the rest, eligibility is most commonly based on HIV status and abnormal anal cytology results. Fifty-three percent of clinics require abnormal anal cytology prior to performing high-resolution anoscopy (HRA) in asymptomatic patients. Almost all clinics offer both anal cytology and HRA. Internal high-grade anal intraepithelial neoplasia (AIN) is most often treated with infrared coagulation (61%), whereas external high-grade AIN is most commonly treated with imiquimod (49%). Most procedures are performed by physicians, followed by nurse practitioners. Our study is the first description of global anal cancer screening practices. Our findings may be used to inform practice and health policy in jurisdictions considering anal cancer screening

  8. Environmental scan of anal cancer screening practices: worldwide survey results.

    Science.gov (United States)

    Patel, Jigisha; Salit, Irving E; Berry, Michael J; de Pokomandy, Alexandra; Nathan, Mayura; Fishman, Fred; Palefsky, Joel; Tinmouth, Jill

    2014-08-01

    Anal squamous cell carcinoma is rare in the general population but certain populations, such as persons with HIV, are at increased risk. High-risk populations can be screened for anal cancer using strategies similar to those used for cervical cancer. However, little is known about the use of such screening practices across jurisdictions. Data were collected using an online survey. Health care professionals currently providing anal cancer screening services were invited to complete the survey via email and/or fax. Information was collected on populations screened, services and treatments offered, and personnel. Over 300 invitations were sent; 82 providers from 80 clinics around the world completed the survey. Fourteen clinics have each examined more than 1000 patients. Over a third of clinics do not restrict access to screening; in the rest, eligibility is most commonly based on HIV status and abnormal anal cytology results. Fifty-three percent of clinics require abnormal anal cytology prior to performing high-resolution anoscopy (HRA) in asymptomatic patients. Almost all clinics offer both anal cytology and HRA. Internal high-grade anal intraepithelial neoplasia (AIN) is most often treated with infrared coagulation (61%), whereas external high-grade AIN is most commonly treated with imiquimod (49%). Most procedures are performed by physicians, followed by nurse practitioners. Our study is the first description of global anal cancer screening practices. Our findings may be used to inform practice and health policy in jurisdictions considering anal cancer screening. PMID:24740973

  9. Research Initiatives and Preliminary Results In Automation Design In Airspace Management in Free Flight

    Science.gov (United States)

    Corker, Kevin; Lebacqz, J. Victor (Technical Monitor)

    1997-01-01

    The NASA and the FAA have entered into a joint venture to explore, define, design and implement a new airspace management operating concept. The fundamental premise of that concept is that technologies and procedures need to be developed for flight deck and ground operations to improve the efficiency, the predictability, the flexibility and the safety of airspace management and operations. To that end NASA Ames has undertaken an initial development and exploration of "key concepts" in the free flight airspace management technology development. Human Factors issues in automation aiding design, coupled aiding systems between air and ground, communication protocols in distributed decision making, and analytic techniques for definition of concepts of airspace density and operator cognitive load have been undertaken. This paper reports the progress of these efforts, which are not intended to definitively solve the many evolving issues of design for future ATM systems, but to provide preliminary results to chart the parameters of performance and the topology of the analytic effort required. The preliminary research in provision of cockpit display of traffic information, dynamic density definition, distributed decision making, situation awareness models and human performance models is discussed as they focus on the theme of "design requirements".

  10. A color spectrographic phonocardiography (CSP applied to the detection and characterization of heart murmurs: preliminary results

    Directory of Open Access Journals (Sweden)

    Hassani Kamran

    2011-05-01

    Full Text Available Abstract Background Although cardiac auscultation remains important to detect abnormal sounds and murmurs indicative of cardiac pathology, the application of electronic methods remains seldom used in everyday clinical practice. In this report we provide preliminary data showing how the phonocardiogram can be analyzed using color spectrographic techniques and discuss how such information may be of future value for noninvasive cardiac monitoring. Methods We digitally recorded the phonocardiogram using a high-speed USB interface and the program Gold Wave http://www.goldwave.com in 55 infants and adults with cardiac structural disease as well as from normal individuals and individuals with innocent murmurs. Color spectrographic analysis of the signal was performed using Spectrogram (Version 16 as a well as custom MATLAB code. Results Our preliminary data is presented as a series of seven cases. Conclusions We expect the application of spectrographic techniques to phonocardiography to grow substantially as ongoing research demonstrates its utility in various clinical settings. Our evaluation of a simple, low-cost phonocardiographic recording and analysis system to assist in determining the characteristic features of heart murmurs shows promise in helping distinguish innocent systolic murmurs from pathological murmurs in children and is expected to useful in other clinical settings as well.

  11. Properties of ABNT 41xx and 86xx cast steel modified with niobium; evaluation methodology and experimental preliminary results

    International Nuclear Information System (INIS)

    The experimental methodology to evaluate the mechanical properties of ABNT 41xx and 86xx steels modified with NB in the as cast and heat treated conditions and the first preliminary results obtained in a laboratory scale, are presented. (Author)

  12. Preliminary assessment of the Long Island National Wildlife Refuge Complex Environmental contaminants background survey: Second year results

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report represents the preliminary results of the second year of the multiyear study, The Long Island National Wildlife Refuge Complex (Complex) Environmental...

  13. Preliminary assessment of the Long Island National Wildlife Refuge Complex environmental contaminants background study: Fifth year results

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report represents the preliminary results of the fifth year of the multiyear study entitled, "The Long Island National Wildlife Refuge Complex (Complex)...

  14. 78 FR 54864 - Light-Walled Rectangular Pipe and Tube From Mexico: Preliminary Results and Partial Rescission of...

    Science.gov (United States)

    2013-09-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE International Trade Administration Light-Walled Rectangular Pipe and Tube From Mexico: Preliminary Results and..., International Trade Administration, Department of Commerce. SUMMARY: The Department of Commerce (the...

  15. 78 FR 48647 - Certain Circular Welded Non-Alloy Steel Pipe from Mexico: Preliminary Results and Partial...

    Science.gov (United States)

    2013-08-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE International Trade Administration Certain Circular Welded Non-Alloy Steel Pipe from Mexico: Preliminary Results... Administration, International Trade Administration, Department of Commerce. SUMMARY: In response to requests...

  16. Digital Processing and Segmentation of Breast Microcalcifications Images Obtained by a Si Microstrips Detector: Preliminary Results

    Science.gov (United States)

    Díaz, Claudia. C.; Angulo, Abril A.

    2007-02-01

    We present the preliminary results of digital processing and segmentation of breast microcalcifications images. They were obtained using a Bede X ray tube with Cu anode, which was fixed at 20 kV and 1 mA. Different biopsies were scanned using a 128 Si microstrips detector. Total scanning resulted in a data matrix, which corresponded with the image of each biopsy. We manipulated the contrast of the images using histograms and filters in the frequency domain in Matlab. Then we intended to investigate about different contour models for the segmentation of microcalcifications boundaries, which were based on the contrast and shape of the image. These algorithms could be applied to mammographic images, which may be obtained by digital mammography or digitizing conventional mammograms.

  17. Preliminary results: shale gas assessment project of the Kettle Point formation, Southern Ontario

    Energy Technology Data Exchange (ETDEWEB)

    Beland Otis, Catherine [Ontario Geological Survey (Canada)

    2010-07-01

    The Kettle Point formation, situated in southern Ontario, is an Upper Devonian unit. In the course of a project of the Ontario Geological Survey, the formation was identified, amongst others, as a promising shale gas unit, due to its high organic content. The formation was therefore selected for the second phase of this study, which aimed at assessing its shale gas potential. Two boreholes have were drilled and sampled and a core sample was collected. The samples were stored in a specialized canister and analyzed for gas concentration and other important parameters. Results showed an important difference in gas quantities in the two wells, indicating that the gas has two origins within the formation. The preliminary results are not sufficient to determine if the formation is economically viable. This study constitutes a step towards the assessment of the gas potential of the Kettle Point formation and further hydrogeological work needs to be undertaken.

  18. Hybrid Spectral Micro-CT: System Design, Implementation, and Preliminary Results

    CERN Document Server

    Bennett, James R; Xu, Qiong; Yu, Hengyong; Walsh, Michael; Butler, Anthony; Butler, Phillip; Cao, Guohua; Mohs, Aaron; Wang, Ge

    2014-01-01

    Spectral CT has proven an important development in biomedical imaging, and there have been several publications in the past years demonstrating its merits in pre-clinical and clinical applications. In 2012, Xu et al. reported that near-term implementation of spectral micro-CT could be enhanced by a hybrid architecture: a narrow-beam spectral "interior" imaging chain integrated with a traditional wide-beam "global" imaging chain. This hybrid integration coupled with compressive sensing (CS)-based interior tomography demonstrated promising results for improved contrast resolution, and decreased system cost and radiation dose. The motivation for the current study is implementation and evaluation of the hybrid architecture with a first-of-its-kind hybrid spectral micro-CT system. Preliminary results confirm improvements in both contrast and spatial resolution. This technology is shown to merit further investigation and potential application in future spectral CT scanner design.

  19. MAX-DOAS measurements of tropospheric NO2 over San Salvador: preliminary results

    Science.gov (United States)

    Alberti, Carlos; Wagner, Thomas

    2015-04-01

    We present the first Multi-AXis-Differential Optical Absorption Spectroscopy (MAX-DOAS) measurements at San Salvador. MAX-DOAS observes spectra of scattered sun light taken at different elevation angles. From the spectra the so called slant column density (SCD, the integrated trace gas concentration along the atmospheric light path) is derived. We quantify the dSCD of NO2 at different measurement conditions. From the measured NO2 SCDs we calculate the tropospheric vertical column density using the so called geometric approximation. The preliminary results of this MAX DOAS observations and the diurnal variation of the retrieved trace gas dSCDs will be presented. We also use the MAX-DOAS results for the validation of satellite observations.

  20. PDM performance Test Results and Preliminary Analysis: Incompressible and Compressible Fluids

    Energy Technology Data Exchange (ETDEWEB)

    Dreesen, D.S.; Gruenhagan, E.; Cohen, J.C.; Moran, D.W.

    1999-02-01

    Three, small diameter, Moineau, positive displacement (drilling) motors (PDMs) were dynamometer tested using water, air-water mist, air-water foam, and aerated water. The motors included (1) a 1.5-inch OD, single-lobe mud motor; (2) a 1.69-inch OD, 5:6 multi-lobe mud motor; and (3) a 1.75-inch OD, 5:6 multi-lobe air motor. This paper describes the test apparatus, procedures, data analysis, and results. Incompressible and compressible fluid performance are compared; linear performance, predicted by a positive displacement motor model, is identified where it occurs. Preliminary results and conclusions are (1) the performance of all three motors is accurately modeled using a two-variable, linear model for incompressible fluid and (2) the model was not successfully adapted to model compressible fluid performance.

  1. RR Lyrae search and stellar populations study in Canis Major: Preliminary Results

    CERN Document Server

    Mateu, C E; Zinn, R; Miller, L; Mateu, Cecilia E.; Zinn, Robert; Miller, Lissa

    2005-01-01

    We present preliminary results of a RR Lyrae star search and stellar populations study performed in the Canis Major overdensity, spanning an area of 8.35sq deg. The observations were made in R and V bands, with the QUEST camera installed in the 1m Jurgen Stock Telescope, at the Venezuela National Observatory. The resulting Hess diagram shows a possible, but weak, red giant branch and no obvious horizontal branch, red clump or main sequence turnoff. After a multi--epoch photometric search, 6 RR Lyrae stars were confirmed with further observations obtained at the 1.0 and 1.3m telescopes of the SMARTS consortium at CTIO. Of these confirmed RR Lyrae stars, 5 have heliocentric distances between 5 and 7 kpc. Confirmation of their physsical association with the Canis Major system awaits for a study of their radial velocities.

  2. Comparison of stroke infarction between CT perfusion and diffusion weighted imaging: preliminary results

    Science.gov (United States)

    Abd. Rahni, Ashrani Aizzuddin; Arka, Israna Hossain; Chellappan, Kalaivani; Mukari, Shahizon Azura; Law, Zhe Kang; Sahathevan, Ramesh

    2016-03-01

    In this paper we present preliminary results of comparison of automatic segmentations of the infarct core, between that obtained from CT perfusion (based on time to peak parameter) and diffusion weighted imaging (DWI). For each patient, the two imaging volumes were automatically co-registered to a common frame of reference based on an acquired CT angiography image. The accuracy of image registration is measured by the overlap of the segmented brain from both images (CT perfusion and DWI), measured within their common field of view. Due to the limitations of the study, DWI was acquired as a follow up scan up to a week after initial CT based imaging. However, we found significant overlap of the segmented brain (Jaccard indices of approximately 0.8) and the percentage of infarcted brain tissue from the two modalities were still fairly highly correlated (correlation coefficient of approximately 0.9). The results are promising with more data needed in future for clinical inference.

  3. Understanding Active Galactic Nuclei using near-infrared high angular resolution polarimetry II: Preliminary results

    CERN Document Server

    Marin, F; Goosmann, R; Gratadour, D; Rouan, D; Clénet, Y; Pelat, D; Lobos, P Andrea Rojas

    2016-01-01

    In this second research note of a series of two, we present the first near-infrared results we obtained when modeling Active Galactic Nuclei (AGN). Our first proceedings showed the comparison between the MontAGN and STOKES Monte Carlo codes. Now we use our radiative transfer codes to simulate the polarization maps of a prototypical, NGC 1068-like, type-2 radio-quiet AGN. We produced high angular resolution infrared (1 micron) polarization images to be compared with recent observations in this wavelength range. Our preliminary results already show a good agreement between the models and observations but cannot account for the peculiar linear polarization angle of the torus such as observed. Gratadour et al. 2015 found a polarization position angle being perpendicular to the bipolar outflows axis. Further work is needed to improve the models by adding physical phenomena such as dichroism and clumpiness.

  4. Measurement of pressure ridges in SAR images of sea ice - Preliminary results on scattering theory

    Science.gov (United States)

    Vesecky, J. F.; Smith, M. P.; Daida, J. M.; Samadani, R.; Camiso, J. C.

    1992-01-01

    Sea ice ridges and keels (hummocks and bummocks) are important in sea ice research for both scientific and practical reasons. A long-term objective is to make quantitative measurements of sea ice ridges using synthetic aperture radar (SAR) images. The preliminary results of a scattering model for sea ice ridge are reported. The approach is through the ridge height variance spectrum Psi(K), where K is the spatial wavenumber, and the two-scale scattering model. The height spectrum model is constructed to mimic height statistics observed with an airborne optical laser. The spectrum model is used to drive a two-scale scattering model. Model results for ridges observed at C- and X-band yield normalized radar cross sections that are 10 to 15 dB larger than the observed cross sections of multiyear ice over the range of angles of incidence from 10 to 70 deg.

  5. Finasteride concentrations and prostate cancer risk: results from the Prostate Cancer Prevention Trial.

    Directory of Open Access Journals (Sweden)

    Cindy H Chau

    Full Text Available In the Prostate Cancer Prevention Trial (PCPT, finasteride reduced the risk of prostate cancer by 25%, even though high-grade prostate cancer was more common in the finasteride group. However, it remains to be determined whether finasteride concentrations may affect prostate cancer risk. In this study, we examined the association between serum finasteride concentrations and the risk of prostate cancer in the treatment arm of the PCPT and determined factors involved in modifying drug concentrations.Data for this nested case-control study are from the PCPT. Cases were drawn from men with biopsy-proven prostate cancer and matched controls. Finasteride concentrations were measured using a liquid chromatography-mass spectrometry validated assay. The association of serum finasteride concentrations with prostate cancer risk was determined by logistic regression. We also examine whether polymorphisms in the enzyme target and metabolism genes of finasteride are related to drug concentrations using linear regression.Among men with detectable finasteride concentrations, there was no association between finasteride concentrations and prostate cancer risk, low-grade or high-grade, when finasteride concentration was analyzed as a continuous variable or categorized by cutoff points. Since there was no concentration-dependent effect on prostate cancer, any exposure to finasteride intake may reduce prostate cancer risk. Of the twenty-seven SNPs assessed in the enzyme target and metabolism pathway, five SNPs in two genes, CYP3A4 (rs2242480; rs4646437; rs4986910, and CYP3A5 (rs15524; rs776746 were significantly associated with modifying finasteride concentrations. These results suggest that finasteride exposure may reduce prostate cancer risk and finasteride concentrations are affected by genetic variations in genes responsible for altering its metabolism pathway.ClinicalTrials.gov NCT00288106.

  6. Luminescence Dating of Marine Terrace Sediments Between Trabzon and Rize, Eastern Black Sea Basin: Preliminary Results

    Science.gov (United States)

    Softa, Mustafa; Spencer, Joel Q. G.; Emre, Tahir; Sözbilir, Hasan; Turan, Mehmet

    2016-04-01

    Quaternary marine terraces in the coastal region of Pontides in Northeastern Turkey are valuable archives of past sea level change. Until recently, dates of raised marine terraces undeciphered in the coastal region between Trabzon and Rize because of chronologic limitations. In this paper was to determine ages of the terrace deposits by applying optically stimulated luminescence (OSL) dating methods using single aliquot regenerative dose (SAR) techniques on quartz minerals from extracted marine terraces. Several samples were collected from three orders of Quaternary marine terraces which are reproducible at all sampling location in between cities of Trabzon and Rize, Turkey, coastal of Eastern Pontides, at the front of the thrust system. The terrace deposits mainly consist of clays, silts, sands and gravels. The sediments in these deposits are mainly derived from basaltic, andesitic, and limestone geology, and have elipsoid, square and flat shapes. The terrace deposits have heights ranging from 1 to 17 meters and increases in height and thickness from west to east. Initial OSL results from 1 mm and 3 mm quartz aliquots demonstrate good luminescence characteristics. Preliminary equivalent dose analysis results ranging from 17.6 Gy to 79.6 Gy have been calculated using the Central Age Model (CAM) and Minimum Age Model (MAM). According to ages obtained from three separate terrace is ~8 ka, ~42 ka and ~78 ka, respectively. Results of marine terrace sediments indicate this region has three sedimentation periods and coastal region of Pontides has been remarkably tectonically active since latest Pleistocene to earlier Holocene. This study will present preliminary OSL dating results obtained from samples of Quaternary marine terrace formation. Keywords: optically stimulated luminescence (OSL) dating, single grain, marine terraces, Eastern Pontides.

  7. Subduction of Serpentinized and Weathered Ultramafic Rocks in the Puerto Rico Trench: Preliminary Results

    Science.gov (United States)

    Horning, G.; Klein, F.

    2012-12-01

    Exposure of mantle peridotite and its interactions with seawater to form serpentinite are integral parts of seafloor spreading, and play a key role in affecting the rheology, chemistry, and microbial habitability of the oceanic lithosphere at slow- and ultra-slow spreading ridges. Away from the spreading centers, within subduction zones, the formation and dehydration of serpentinized peridotite impacts seismicity, element cycling, and melt generation. Here we present preliminary results of a petrographic and spectroscopic study of altered rocks recovered from the from the north wall of the trench Puerto Rico Trench (PRT). In fact, the PRT represents one of two subduction zones worldwide where slow spreading oceanic lithosphere is presently subducted, and where serpentinized peridotite has been directly evidenced by seafloor sampling {Bowin, 1966}. Thin section petrography, XRF analysis, scanning electron microscopy, and confocal Raman spectroscopy reveal that the peridotite, which in all likelihood originated at the Mid-Atlantic Ridge during the early Cretaceous, was virtually completely serpentinized under static conditions (as it is evidenced by the preserved mesh texture after olivine and bastite after orthopyroxene), and underwent subsequent seafloor weathering. While it is questionable where exactly serpentinization and subsequent seafloor weathering took place, our preliminary results strongly suggest that the material presently subducted in the PRT is not simply composed of serpentine, magnetite, and brucite; it is rather a complex disequilibrium assemblage of minerals including serpentine, brucite, chlorite, talc, magnetite, hematite, goethite, sulfur-rich sulfides and various clay minerals. Furthermore, our results imply that serpentinite and its weathering products influence the loci of dehydration and mineral replacement reactions, as well as the water input and element recycling in subduction zones.

  8. Preliminary study on the potential of polysaccharide from indigenous Tiger's Milk mushroom (Lignosus rhinocerus) as anti-lung cancer agent

    Science.gov (United States)

    Lai, Wei Hong; Zainal, Zamri; Daud, Fauzi

    2014-09-01

    Tiger's Milk mushroom is a tropical polypore genus that can be found in the tropical part of the world in Australia, Papua New Guinea, Philippines, Indonesia, Malaysia, Sri Lanka and Vanuatu. In Malaysia, Lignosus rhinocerus is the most sought after medicinal mushroom by Semai aborigine upon request by local herbalist. This priced mushroom has been used traditionally to treat various diseases such as asthma, breast cancer, cough, fever and food poisoning. Current results indicated polysaccharide from sclerotia of indigenous L. rhinocerus extracted through hot water is able to inhibit up to 45% growth of human lung carcinoma. Inhibition is achieved when concentration of polysaccharide are in the range of 4-8 μg/ml. Present preliminary study suggests beta-glucan-rich polysaccharide from sclerotia of indigenous L. rhinocerus has anti-proliferation activity on human lung carcinoma (A549).

  9. Preliminary research on dendritic cells loaded with resistant breast cancer antigens in breast cancer-bearing nude mice

    Institute of Scientific and Technical Information of China (English)

    Wei Zhuang; Limin Lun

    2015-01-01

    Objective The aim of the study was to investigate the inhibitory ef ects of dendritic cel s (DCs) loaded with resistant breast cancer antigens on breast cancer in nude mice. Methods A single-cel suspension was prepared from a primary breast cancer and chemotherapeutic drugs were screened using the ATP-PCA susceptibility testing system. Cancer cel s were treated with 1/10 × IC50, 1/5 × IC50, 1/2 × IC50, 1 × IC50, and 2 × IC50 medium until their growth became steady in the 2 × IC50 medium. Peripheral blood mononuclear cel s (PBMCs) were obtained from the peripheral blood of patients with leukapheresis. The obtained adherent cel s were induced by granulocyte-macrophage colony-stimu-lating factor (GM-CSF) and interleukin-4 (IL-4) to generate DCs, which carried resistant strain cel lysis compounds or non-treated cancer cel lysis compounds. The former mature DCs carried resistant breast tumor antigens. A breast tumor-bearing nude mouse model was established with these resistant strains and the mice were randomly divided in three groups. The mice in the treatment group were injected with DCs loaded with resistant breast cancer antigens. The control group consisted of mice injected with DCs loaded with primary tumor cel antigens and the blank group consisted of mice injected with the same volume of normal saline. Changes in the cancers were observed. Results After treatment with the ef ector cel s, the cancer volume and weight were significantly dif erent to those before treatment in every group of mice (P Conclusion DCs loaded with resistant breast cancer antigens demonstrated a significant inhibition ef ect on the cancers of breast tumor-bearing nude mice.

  10. Instrumentation development for space debris optical observation system in Indonesia: Preliminary results

    Science.gov (United States)

    Dani, Tiar; Rachman, Abdul; Priyatikanto, Rhorom; Religia, Bahar

    2015-09-01

    An increasing number of space junk in orbit has raised their chances to fall in Indonesian region. So far, three debris of rocket bodies have been found in Bengkulu, Gorontalo and Lampung. LAPAN has successfully developed software for monitoring space debris that passes over Indonesia with an altitude below 200 km. To support the software-based system, the hardware-based system has been developed based on optical instruments. The system has been under development in early 2014 which consist of two systems: the telescopic system and wide field system. The telescopic system uses CCD cameras and a reflecting telescope with relatively high sensitivity. Wide field system uses DSLR cameras, binoculars and a combination of CCD with DSLR Lens. Methods and preliminary results of the systems will be presented.

  11. Self-potential time series analysis in a seismic area of the Southern Apennines: preliminary results

    Directory of Open Access Journals (Sweden)

    V. Tramutoli

    1994-06-01

    Full Text Available The self-potential time series recorded during the period May 1991 - August 1992 by an automatic station, located in a seismic area of Southern Apennines, is analyzed. We deal with the spectral and the statistical features of the electrotellurie precursors: they can play a major role in the approach to seismic prediction. The time-dynamics of the experimental time series is investigated, the cyclic components and the time trends are removed. In particular we consider the influence of external noise, related to anthropic activities and meteoclimatic parameters, and pick out the anomalies from the residual series. Finally we show the preliminary results of the correlation between the anomalies in the time patterns of self-potential data and the earthquakes which occurred in the area.

  12. Microwave frequency sweep interferometer for plasma density measurements in ECR ion sources: Design and preliminary results

    Science.gov (United States)

    Torrisi, Giuseppe; Mascali, David; Neri, Lorenzo; Leonardi, Ornella; Sorbello, Gino; Celona, Luigi; Castro, Giuseppe; Agnello, Riccardo; Caruso, Antonio; Passarello, Santi; Longhitano, Alberto; Isernia, Tommaso; Gammino, Santo

    2016-02-01

    The Electron Cyclotron Resonance Ion Sources (ECRISs) development is strictly related to the availability of new diagnostic tools, as the existing ones are not adequate to such compact machines and to their plasma characteristics. Microwave interferometry is a non-invasive method for plasma diagnostics and represents the best candidate for plasma density measurement in hostile environment. Interferometry in ECRISs is a challenging task mainly due to their compact size. The typical density of ECR plasmas is in the range 1011-1013 cm-3 and it needs a probing beam wavelength of the order of few centimetres, comparable to the chamber radius. The paper describes the design of a microwave interferometer developed at the LNS-INFN laboratories based on the so-called "frequency sweep" method to filter out the multipath contribution in the detected signals. The measurement technique and the preliminary results (calibration) obtained during the experimental tests will be presented.

  13. Description and preliminary results of a meteorological network for high altitudes

    Science.gov (United States)

    Duran-Montejano, L.

    2003-04-01

    A high resolution meteorological network has been implemented for monitoring temperature, relative humidity and precipitation at very high altitudes. The system is made up by a specially designed “terrestrial buoy” for high altitudes of very low power requirement and great robustness. The complete system consists of seven of these terrestrial buoys installed in less than 20 Km2 and with more than one measuring point per 150 m of altitude difference. A brief description of the system is presented with some of the preliminary results, including spatial generalization of the point meteorological data to the whole domain of the network using a simple spatial interpolation algorithm and a high resolution terrain digital model in order to be used as inputs for eco-biological models.

  14. Preliminary Results from Integrating Compton Photon Polarimetry in Hall A of Jefferson Lab

    CERN Document Server

    Parno, D; Benmokhtar, F; Franklin, G; Michaels, R; Nanda, S; Quinn, B; Souder, P

    2011-01-01

    A wide range of nucleon and nuclear structure experiments in Jefferson Lab's Hall A require precise, continuous measurements of the polarization of the electron beam. In our Compton polarimeter, electrons are scattered off photons in a Fabry-Perot cavity; by measuring an asymmetry in the integrated signal of the scattered photons detected in a GSO crystal, we can make non-invasive, continuous measurements of the beam polarization. Our goal is to achieve 1% statistical error within two hours of running. We discuss the design and commissioning of an upgrade to this apparatus, and report preliminary results for experiments conducted at beam energies from 3.5 to 5.9 GeV and photon rates from 5 to 100 kHz.

  15. Preliminary Results from VOC measurements in the Lower Fraser Valley in July/Aug 2012

    Science.gov (United States)

    Schiller, C. L.; Jones, K.; Vingarzan, R.; Leaitch, R.; Macdonald, A.; Osthoff, H. D.; Reid, K.

    2012-12-01

    In July/August 2012, a pilot study looking at the effect of ClNO2 production on the ozone concentrations in the lower Fraser valley near Abbotsford, BC was conducted. The lower Fraser valley in British Columbia Canada has some of the highest ozone concentrations and visibility issues in Canada. Abbotsford is located approximately 80 kms east of Vancouver, BC and approximately 30 kms from the ocean. The site was located in a largely agricultural area with fruit farms (raspberries and blueberries) and poultry barns predominating. During the study biogenic and anthropogenic VOCs were measured in situ using a GCMS/FID with hourly samples. Particle composition was measured using an ACSM and size distribution using an SMPS. Preliminary results from the study will be discussed.

  16. Preliminary results for the diffusion of water into fibre optic oil well sensors

    International Nuclear Information System (INIS)

    Preliminary results are presented on a measurement technique for determination of water penetration into fibre optic sensors under high pressure, high temperature conditions. Both fibre optic sensors and communication fibres were subjected to prolonged treatment in heavy water at temperatures up to 250 deg. C and pressures of 40 bar. Deuterium penetration is measured by a nuclear reaction technique based on a 3He micro-focussed ion beam, which permits two-dimensional mapping of the deuterium penetration into cleaved fibres. Water penetration can be detected whilst still confined to the cladding, well before any optical effects become apparent, permitting prediction of likely fibre lifetime under down-hole conditions after realistic experimental times

  17. Microwave frequency sweep interferometer for plasma density measurements in ECR ion sources: Design and preliminary results

    International Nuclear Information System (INIS)

    The Electron Cyclotron Resonance Ion Sources (ECRISs) development is strictly related to the availability of new diagnostic tools, as the existing ones are not adequate to such compact machines and to their plasma characteristics. Microwave interferometry is a non-invasive method for plasma diagnostics and represents the best candidate for plasma density measurement in hostile environment. Interferometry in ECRISs is a challenging task mainly due to their compact size. The typical density of ECR plasmas is in the range 1011–1013 cm−3 and it needs a probing beam wavelength of the order of few centimetres, comparable to the chamber radius. The paper describes the design of a microwave interferometer developed at the LNS-INFN laboratories based on the so-called “frequency sweep” method to filter out the multipath contribution in the detected signals. The measurement technique and the preliminary results (calibration) obtained during the experimental tests will be presented

  18. Microwave frequency sweep interferometer for plasma density measurements in ECR ion sources: Design and preliminary results.

    Science.gov (United States)

    Torrisi, Giuseppe; Mascali, David; Neri, Lorenzo; Leonardi, Ornella; Sorbello, Gino; Celona, Luigi; Castro, Giuseppe; Agnello, Riccardo; Caruso, Antonio; Passarello, Santi; Longhitano, Alberto; Isernia, Tommaso; Gammino, Santo

    2016-02-01

    The Electron Cyclotron Resonance Ion Sources (ECRISs) development is strictly related to the availability of new diagnostic tools, as the existing ones are not adequate to such compact machines and to their plasma characteristics. Microwave interferometry is a non-invasive method for plasma diagnostics and represents the best candidate for plasma density measurement in hostile environment. Interferometry in ECRISs is a challenging task mainly due to their compact size. The typical density of ECR plasmas is in the range 10(11)-10(13) cm(-3) and it needs a probing beam wavelength of the order of few centimetres, comparable to the chamber radius. The paper describes the design of a microwave interferometer developed at the LNS-INFN laboratories based on the so-called "frequency sweep" method to filter out the multipath contribution in the detected signals. The measurement technique and the preliminary results (calibration) obtained during the experimental tests will be presented. PMID:26932081

  19. Fuzzy-logic-based hybrid locomotion mode classification for an active pelvis orthosis: Preliminary results.

    Science.gov (United States)

    Yuan, Kebin; Parri, Andrea; Yan, Tingfang; Wang, Long; Munih, Marko; Vitiello, Nicola; Wang, Qining

    2015-01-01

    In this paper, we present a fuzzy-logic-based hybrid locomotion mode classification method for an active pelvis orthosis. Locomotion information measured by the onboard hip joint angle sensors and the pressure insoles is used to classify five locomotion modes, including two static modes (sitting, standing still), and three dynamic modes (level-ground walking, ascending stairs, and descending stairs). The proposed method classifies these two kinds of modes first by monitoring the variation of the relative hip joint angle between the two legs within a specific period. Static states are then classified by the time-based absolute hip joint angle. As for dynamic modes, a fuzzy-logic based method is proposed for the classification. Preliminary experimental results with three able-bodied subjects achieve an off-line classification accuracy higher than 99.49%.

  20. THE BREED TRACEABILITY OF SHEEP MEAT BY USING MOLECULAR GENETICS METHODS: PRELIMINARY RESULTS

    Directory of Open Access Journals (Sweden)

    A. Bramante

    2011-04-01

    Full Text Available Safety and quality foods of animal origin are extremely important for consumers. The aim of this work was to evaluate the feasibility of a method to track the breed origin of sheep meat all along the production chain using molecular genetics tools. A total of 800 samples evenly distributed among seven Italian sheep breeds have been typed at 19 STR markers, together with 90 samples from both imported sheep animals and local crossbred animals withdrawn at slaughterhouses. A maximum likelihood assignment test was adopted to evaluate STR ability to allocate samples to their true breed of origin. Sarda animals were all correctly allocated, as well as more than 98% of samples from the other breeds. Only slightly worst allocation performances were observed for imported and crossbred animals. Preliminary results seem quite promising, though further analyses will be needed in order to better understand the statistical power of such an assignment test before implementation in the sheep meat production chain.

  1. Spectral monitoring of AGNSs: Preliminary results for Ark 564 and Arp 102B

    CERN Document Server

    Shapovalova, A I; Ilic, D; Kovacevic, A; Kovacevic, J; Burenkov, A N; Chavushyan, V H

    2012-01-01

    We present preliminary results of the long term spectral monitoring of two active galactic nuclei with different broad line shapes: Ark 564 and Arp 102B. Ark 564 is a bright nearby narrow line Syfert 1 (NLS1) galaxy with relatively narrow permitted optical emission lines and a high FeII/H${\\beta}$ ratio, while Arp 102B is a nearby broad-line radio galaxy with broad double-peaked Balmer emission lines. The spectra of Ark 564 were observed during 11-year period (1999-2009) and the spectra of Arp 102B in the 12-year period (1998-2009), with SAO 6-m and 1-m telescopes (Russia) and the GHAO 2.1-m telescope (Cananea, Mexico).

  2. Fuzzy-logic-based hybrid locomotion mode classification for an active pelvis orthosis: Preliminary results.

    Science.gov (United States)

    Yuan, Kebin; Parri, Andrea; Yan, Tingfang; Wang, Long; Munih, Marko; Vitiello, Nicola; Wang, Qining

    2015-08-01

    In this paper, we present a fuzzy-logic-based hybrid locomotion mode classification method for an active pelvis orthosis. Locomotion information measured by the onboard hip joint angle sensors and the pressure insoles is used to classify five locomotion modes, including two static modes (sitting, standing still), and three dynamic modes (level-ground walking, ascending stairs, and descending stairs). The proposed method classifies these two kinds of modes first by monitoring the variation of the relative hip joint angle between the two legs within a specific period. Static states are then classified by the time-based absolute hip joint angle. As for dynamic modes, a fuzzy-logic based method is proposed for the classification. Preliminary experimental results with three able-bodied subjects achieve an off-line classification accuracy higher than 99.49%. PMID:26737144

  3. Preliminary Results on the Experimental Investigation of the Structure Functions of Bound Nucleons

    Energy Technology Data Exchange (ETDEWEB)

    Bodek, Arie [University of Rochester, Rochester, NY

    2015-09-01

    We present preliminary results on an experimental study of the nuclear modification of the longitudinal (σL) and transverse (σT) structure functions of nucleons bound in nuclear targets. The origin of these modifications (commonly referred as as the EMC effect) is not fully understood. Our measurements of R= σLT for nuclei (RA) and for deuterium (RD) indicate that nuclear modifications of the structure functions of bound nucleons are different for the longitudinal and transverse structure functions, and that contrary to expectation from several theoretical models, RA < RD.

  4. Microwave frequency sweep interferometer for plasma density measurements in ECR ion sources: Design and preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Torrisi, Giuseppe [INFN - Laboratori Nazionali del Sud, Via S. Sofia 62, 95125 Catania (Italy); University Mediterranea of Reggio Calabria, Reggio Calabria (Italy); Mascali, David; Neri, Lorenzo; Leonardi, Ornella; Celona, Luigi; Castro, Giuseppe; Agnello, Riccardo; Caruso, Antonio; Passarello, Santi; Longhitano, Alberto; Gammino, Santo [INFN - Laboratori Nazionali del Sud, Via S. Sofia 62, 95125 Catania (Italy); Sorbello, Gino [INFN - Laboratori Nazionali del Sud, Via S. Sofia 62, 95125 Catania (Italy); University of Catania, Catania, Italy and INFN-LNS, Catania (Italy); Isernia, Tommaso [University Mediterranea of Reggio Calabria, Reggio Calabria (Italy)

    2016-02-15

    The Electron Cyclotron Resonance Ion Sources (ECRISs) development is strictly related to the availability of new diagnostic tools, as the existing ones are not adequate to such compact machines and to their plasma characteristics. Microwave interferometry is a non-invasive method for plasma diagnostics and represents the best candidate for plasma density measurement in hostile environment. Interferometry in ECRISs is a challenging task mainly due to their compact size. The typical density of ECR plasmas is in the range 10{sup 11}–10{sup 13} cm{sup −3} and it needs a probing beam wavelength of the order of few centimetres, comparable to the chamber radius. The paper describes the design of a microwave interferometer developed at the LNS-INFN laboratories based on the so-called “frequency sweep” method to filter out the multipath contribution in the detected signals. The measurement technique and the preliminary results (calibration) obtained during the experimental tests will be presented.

  5. Spatial and temporal variation of radiocarbon in tree rings - some preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Higham, T.F.G.; Hogg, A.G. [Waikato Univ., Hamilton (New Zealand); McCormac, F.G.; Baillie, M.G.L.; Brown, D. [Queens`s University, Belfast, (Ireland). School of Geosciences; Palmer, J.G.; Xiong, L. [Lincoln University, Canterbury (New Zealand). Department of Plant Science

    1997-12-31

    A number of researchers have identified a measurable difference between the {sup 14}C activities of tree rings of identical dendochronological age between the Northern and the Southern Hemispheres. It is also acknowledged that there is an urgent need for new high precision {Delta}{sup 14}C data from tree rings in both Hemispheres to help resolve the questions relating to the magnitude and cause of the locality and temporal dependence of the {Delta}{sup 14}C record, to provide a reliable Southern Hemisphere calibration curve and to throw light upon the 1986 and 1993 Calibration data set discrepancies. In this paper, the authors present the research design of a project to investigate these critical issues in radiocarbon age calibration and describe the preliminary results. Paper no. 30; Extended abstract; 12 refs.

  6. Preliminary results of 3-dimensional conformal radiotherapy for primary unresectable hepatocellular carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Keum, Ki Chang; Park, Hee Chul; Seong, Jin Sil; Chang, Sei Kyoung; Han, Kwang Hyub; Chon, Chae Yoon; Moon, Young Myoung; Kim, Gwi Eon; Suh, Chang Ok [Hallym University College of Medicine, Seoul (Korea, Republic of)

    2002-06-15

    The purpose of this study was to determine the potential role of three-dimensional conformal radiotherapy (3D-CRT) in the treatment of primary unresectable hepatocellular carcinoma. The preliminary results on the efficacy and the toxicity of 3D-CRT are reported. Seventeen patients were enrolled in this study, which was conducted prospectively from January 1995 to June 1997. The exclusion criteria included the presence of extrahepatic metastasis, liver cirrhosis of Child-Pugh classification C, tumors occupying more than two thirds of the entire liver, and a performance status of more than 3 on the ECOG scale. Two patients were treated with radiotherapy only while the remaining 15 were treated with combined transcatheter arterial chemoembolization. Radiotherapy was given to the field including the tumor plus a 1.5 cm margin using a 3D-CRT technique. The radiation dose ranged from 36 {approx} 60 Gy (median: 59.4 Gy). Tumor response was based on a radiological examination such as the CT scan, MR imaging, and hepatic artery angiography at 4 {approx} 8 weeks following the completion of treatment. The acute and subacute toxicities were monitored. An objective response was observed in 11 out of 17 patients, giving a response rate of 64.7%. The actuarial survival rate at 2 years was 21.2% from the start of radiotherapy (median survival; 19 months). Six patients developed a distant metastasis consisting of a lung metastasis in 5 patients and bone metastasis in one. The complications related to 3D-CRT were gastro-duodenitis ({>=} grade 2) in 2 patients. There were no treatment related deaths and radiation induced hepatitis. The preliminary results show that 3D-CRT is a reliable and effective treatment modality for primary unresectable hepatocellular carcinoma compared to other conventional modalities. Further studies to evaluate the definitive role of the 3D-CRT technique in the treatment of primary unresectable hepatocellular carcinoma are needed.

  7. Preliminary results of 3-dimensional conformal radiotherapy for primary unresectable hepatocellular carcinoma

    International Nuclear Information System (INIS)

    The purpose of this study was to determine the potential role of three-dimensional conformal radiotherapy (3D-CRT) in the treatment of primary unresectable hepatocellular carcinoma. The preliminary results on the efficacy and the toxicity of 3D-CRT are reported. Seventeen patients were enrolled in this study, which was conducted prospectively from January 1995 to June 1997. The exclusion criteria included the presence of extrahepatic metastasis, liver cirrhosis of Child-Pugh classification C, tumors occupying more than two thirds of the entire liver, and a performance status of more than 3 on the ECOG scale. Two patients were treated with radiotherapy only while the remaining 15 were treated with combined transcatheter arterial chemoembolization. Radiotherapy was given to the field including the tumor plus a 1.5 cm margin using a 3D-CRT technique. The radiation dose ranged from 36 ∼ 60 Gy (median: 59.4 Gy). Tumor response was based on a radiological examination such as the CT scan, MR imaging, and hepatic artery angiography at 4 ∼ 8 weeks following the completion of treatment. The acute and subacute toxicities were monitored. An objective response was observed in 11 out of 17 patients, giving a response rate of 64.7%. The actuarial survival rate at 2 years was 21.2% from the start of radiotherapy (median survival; 19 months). Six patients developed a distant metastasis consisting of a lung metastasis in 5 patients and bone metastasis in one. The complications related to 3D-CRT were gastro-duodenitis (≥ grade 2) in 2 patients. There were no treatment related deaths and radiation induced hepatitis. The preliminary results show that 3D-CRT is a reliable and effective treatment modality for primary unresectable hepatocellular carcinoma compared to other conventional modalities. Further studies to evaluate the definitive role of the 3D-CRT technique in the treatment of primary unresectable hepatocellular carcinoma are needed

  8. The 2003 Australian Breast Health Survey: survey design and preliminary results

    Directory of Open Access Journals (Sweden)

    Favelle Simone

    2008-01-01

    Full Text Available Abstract Background The Breast Health Surveys, conducted by the National Breast Cancer Centre (NBCC in 1996 and 2003, are designed to gain insight into the knowledge, attitudes and behaviours of a nationally representative sample of Australian women on issues relevant to breast cancer. In this article, we focus on major aspects of the design and present results on respondents' knowledge about mammographic screening. Methods The 2003 BHS surveyed English-speaking Australian women aged 30–69 without a history of breast cancer using computer-assisted telephone interviewing. Questions covered the following themes: knowledge and perceptions about incidence, mortality and risk; knowledge and behaviour regarding early detection, symptoms and diagnosis; mammographic screening; treatment; and accessibility and availability of information and services. Respondents were selected using a complex sample design involving stratification. Sample weights against Australian population benchmarks were used in all statistical analyses. Means and proportions for the entire population and by age group and area of residence were calculated. Statistical tests were conducted using a level of significance of 0.01. Results Of the 3,144 respondents who consented to being interviewed, 138 (4.4% had a previous diagnosis of breast cancer and were excluded leaving 3,006 completed interviews eligible for analysis. A majority of respondents (61.1% reported ever having had a mammogram and 29.1% identified mammography as being the best way of finding breast cancer. A majority of women (85.9% had heard of the BreastScreen Australia (BSA program, the national mammographic screening program providing free biennial screening mammograms, with 94.5% believing that BSA attendance was available regardless of the presence or absence of symptoms. There have been substantial gains in women's knowledge about mammographic screening over the seven years between the two surveys. Conclusion The

  9. Results of combination treatment for triple-negative breast cancer

    OpenAIRE

    M. A. Sekundova; V.I. Borisov; A. M. Sdvizhkov

    2014-01-01

    The authors give the results of treatment in 128 patients with operable triple-negative breast cancer (BC). All the patients underwent surgical intervention, the volume of which depended on the stage of the disease. The efficiency of adjuvant and neoadjuvant chemotherapy, as well as pre- and postoperative radiotherapy was evaluated. The side effects of different treatment options were analyzed. Five-year relapse-free and overall survival rates were traced in this patient group. It is conclude...

  10. Results of lung cancer screening in atomic bomb survivors

    International Nuclear Information System (INIS)

    Risk of lung cancer in A-bomb survivors is reportedly increased. The screening in the title has been conducted since 1988 and this report summarizes its results of the latest 6-year term (2004-2009). The total number of subjects who visited authors' facility for the screening in the period was 39,147 men (average age 70.6 y) and 45,351 women (71.8 y), of the age range of 60-89 y. The screening results of the cancer were examined concerning with sex, age and exposure situation. As well, the relationship between the found cancer incidence and exposure in never, formerly and currently smoking subjects were also examined. Exposure situation was divided in 3 groups of the exposure by entrance in the city/by other reasons, within 2 km close (Close, C) to, and out of 2.1 km afar (Distant, D) from, the city. Statistic analysis was performed by Chi-squire and/or Fisher's exact test. The index of positive finding in the screening of the lung cancer per 1,000 subjects was the highest in C men of ages 70s, 2.88 subjects, which was statistically significant from 0.85 in D men of the same generation. In current smokers, the index 5.40 in C men of ages 70s was significantly higher than 0.90 in D men of the same generation. Overall, positive results tended to be high in survivors of C regardless to sex and smoking, and was significantly high in current smokers of C as above, both implying the particular necessity of promotion to stop smoking in survivors. (T.T.)

  11. Acute Vs Delayed ACL Reconstruction. Early Differences and Preliminary Two Year Results

    Science.gov (United States)

    Eriksson, Karl; Barenius, Björn

    2016-01-01

    acute group at 2 years compared to 78 in the delayed group (p=0.2). At the meeting preliminary results regarding functional tests and additional procedures for the groups will be presented. Conclusion: No negative effects of an acute ACL reconstruction were found at 6 months follow up. Preliminary 2 year results point in the same direction. Acute reconstruction of the ACL seems to be safe and a potential benefit might be decreased loss of muscle function. Further analysis of the 2 year results is needed before final conclusions can be drawn.

  12. Robotic image-guided reirradiation of lateral pelvic recurrences: preliminary results

    Directory of Open Access Journals (Sweden)

    Castelain Bernard

    2011-06-01

    Full Text Available Abstract Background The first-line treatment of a pelvic recurrence in a previously irradiated area is surgery. Unfortunately, few patients are deemed operable, often due to the location of the recurrence, usually too close to the iliac vessels, or the associated surgical morbidity. The objective of this study is to test the viability of robotic image-guided radiotherapy as an alternative treatment in inoperable cases. Methods Sixteen patients previously treated with radiotherapy were reirradiated with CyberKnife® for lateral pelvic lesions. Recurrences of primary rectal cancer (4 patients, anal canal (6, uterine cervix cancer (4, endometrial cancer (1, and bladder carcinoma (1 were treated. The median dose of the previous treatment was 45 Gy (EqD2 range: 20 to 96 Gy. A total dose of 36 Gy in six fractions was delivered with the CyberKnife over three weeks. The responses were evaluated according to RECIST criteria. Results Median follow-up was 10.6 months (1.9 to 20.5 months. The actuarial local control rate was 51.4% at one year. Median disease-free survival was 8.3 months after CyberKnife treatment. The actuarial one-year survival rate was 46%. Acute tolerance was limited to digestive grade 1 and 2 toxicities. Conclusions Robotic stereotactic radiotherapy can offer a short and well-tolerated treatment for lateral pelvic recurrences in previously irradiated areas in patients otherwise not treatable. Efficacy and toxicity need to be evaluated over the long term, but initial results are encouraging.

  13. Preliminary results of local earthquake tomography around Bali, Lombok, and Sumbawa regions

    International Nuclear Information System (INIS)

    Bali, Sumbawa, and Lombok regions are located in active tectonic influence by Indo-Australia plate subducts beneath Sunda plate in southern part and local back-arc thrust in northern part the region. Some active volcanoes also lie from eastern part of Java, Bali, Lombok and Sumbawa regions. Previous studies have conducted subsurface seismic velocity imaging using regional and global earthquake data around the region. In this study, we used P-arrival time from local earthquake networks compiled by MCGA, Indonesia within time periods of 2009 up to 2013 to determine seismic velocity structure and simultaneously hypocenter adjustment by applying seismic tomography inversion method. For the tomographic inversion procedure, we started from 1-D initial velocity structure. We evaluated the resolution of tomography inversion results through checkerboard test and calculating derivative weigh sum. The preliminary results of tomography inversion show fairly clearly high seismic velocity subducting Indo-Australian and low velocity anomaly around volcano regions. The relocated hypocenters seem to cluster around the local fault system such as back-arc thrust fault in northern part of the region and around local fault in Sumbawa regions. Our local earthquake tomography results demonstrated consistent with previous studies and improved the resolution. For future works, we will determine S-wave velocity structure using S-wave arrival time to enhance our understanding of geological processes and for much better interpretation

  14. Facial emotional recognition in schizophrenia: preliminary results of the virtual reality program for facial emotional recognition

    Directory of Open Access Journals (Sweden)

    Teresa Souto

    2013-01-01

    Full Text Available BACKGROUND: Significant deficits in emotional recognition and social perception characterize patients with schizophrenia and have direct negative impact both in inter-personal relationships and in social functioning. Virtual reality, as a methodological resource, might have a high potential for assessment and training skills in people suffering from mental illness. OBJECTIVES: To present preliminary results of a facial emotional recognition assessment designed for patients with schizophrenia, using 3D avatars and virtual reality. METHODS: Presentation of 3D avatars which reproduce images developed with the FaceGen® software and integrated in a three-dimensional virtual environment. Each avatar was presented to a group of 12 patients with schizophrenia and a reference group of 12 subjects without psychiatric pathology. RESULTS: The results show that the facial emotions of happiness and anger are better recognized by both groups and that the major difficulties arise in fear and disgust recognition. Frontal alpha electroencephalography variations were found during the presentation of anger and disgust stimuli among patients with schizophrenia. DISCUSSION: The developed program evaluation module can be of surplus value both for patient and therapist, providing the task execution in a non anxiogenic environment, however similar to the actual experience.

  15. Design of a Regenerative Life Support System for a Moon Base. Preliminary Results.

    Science.gov (United States)

    Duatis Juarez, Jordi; Guirado, Víctor; Lasseur, Christophe

    NTE-SENER has finalised a study under an ESA contract, to define a preliminary system design of an European Module to provide Environmental Control and Life Support to a potential Moon base. The design is based on current Life Support System technologies under development in Europe (MELiSSA, GWRU, Sabatier Reactor and UTU) along with contamination and microbial detection technologies (ANITA, MIDASS). The ECLSS is sized to provide water, air and up to the 40 As a support to the study a simulator has been developed to analyse the energy, volume and mass and the flow rates and efficiencies of the different components. The study applied the basics of the ALISSE criteria to evaluate the technologies taking as a source the results of the simulations. Detailed models of the different technologies have been developed including feedback from the pilot designs. The results of the study have showed up opportunities of improvement and many points that need to be further investigated. The technologies used in the study are based on the MELiSSA Pilot Plant reactors implementation and the results could affect their design in the near fu-ture in aspects such as carbon recycling, irrigation methods, energy consumption, technologies involved, etc.

  16. Impulsivity in Multiplayer Online Battle Arena Gamers: Preliminary Results on Experimental and Self-Report Measures.

    Science.gov (United States)

    Nuyens, Filip; Deleuze, Jory; Maurage, Pierre; Griffiths, Mark D; Kuss, Daria J; Billieux, Joël

    2016-06-01

    Background and aims Multiplayer Online Battle Arena (MOBA) games have become the most popular type of video games played worldwide, superseding the playing of Massively Multiplayer Online Role-Playing Games and First-Person Shooter games. However, empirical studies focusing on the use and abuse of MOBA games are still very limited, particularly regarding impulsivity, which is an indicator of addictive states but has not yet been explored in MOBA games. In this context, the objective of the present study is to explore the associations between impulsivity and symptoms of addictive use of MOBA games in a sample of highly involved League of Legends (LoL, currently the most popular MOBA game) gamers. Methods Thirty-six LoL gamers were recruited and completed both experimental (Single Key Impulsivity Paradigm) and self-reported impulsivity assessments (s-UPPS-P Impulsive Behavior Scale, Barratt Impulsiveness Scale), in addition to an assessment of problematic video game use (Problematic Online Gaming Questionnaire). Results Results showed links between impulsivity-related constructs and signs of excessive MOBA game involvement. Findings indicated that impaired ability to postpone rewards in an experimental laboratory task was strongly related to problematic patterns of MOBA game involvement. Although less consistent, several associations were also found between self-reported impulsivity traits and signs of excessive MOBA game involvement. Conclusions Despite these results are preliminary and based upon a small (self-selected) sample, the present study highlights potential psychological factors related to the addictive use of MOBA games.

  17. Polyurethane-Covered Self-expandable Nitinol Stent for Malignant Biliary Obstruction: Preliminary Results

    International Nuclear Information System (INIS)

    Purpose: To evaluate the immediate and long-term results in ten patients with malignant biliary obstruction using a polyurethane-covered, self-expandable nitinol stent.Methods: A nitinol stent, fully covered with high-elasticity polyurethane, with an unconstrained diameter of 10 mm and a total length of 60-80 mm, was placed transhepatically under fluoroscopic guidance in ten patients. The length of the biliary obstruction varied between 30-50 mm. The follow-up examination included a clinical assessment, serum bilirubin measurement, and ultrasound examinations at one-month intervals in all patients. Results: Initial stent deployment was successful in eight patients. Two patients experienced proximal migration,which was solved by insertion of two, uncovered Wallstents. One patient had the stent removed after two weeks because of severe nausea and vomiting. One patient had delayed migration of the covered stent after 40 weeks. The follow-up duration was 3-40 weeks (Mean: 16.9 weeks). Seven patients died(3-26 weeks) and three patients survived (24-40 weeks). The bilirubin measurements in all patients had significantly decreased one week after stent insertion. The levels of amylase and lipase had did not increase after stent insertion. Conclusions: Apolyurethane-covered, self-expandable nitinol stent can be used effectively and safely in the treatment of malignant biliary obstruction. The preliminary results are favorable, but there is a need for further large studies to determine both long-term survival and patency

  18. Scientific design and preliminary results of three-dimensional variational data assimilation system of GRAPES

    Institute of Scientific and Technical Information of China (English)

    XUE JiShan; ZHUANG ShiYu; ZHU GuoFu; ZHANG Hua; LIU ZhiQuan; LIU Yan; ZHUANG ZhaoRong

    2008-01-01

    The scientific design and preliminary results of the data assimilation component of the Global-Regional Prediction and Assimilation System (GRAPES) recently developed in China Meteorological Administra-tion (CMA) are presented in this paper. This is a three-dimensional variational (3DVar) assimilation system set up on global and regional grid meshes favorable for direct assimilation of the space-based remote sensing data and matching the frame work of the prediction model GRAPES. The state variables are assumed to decompose balanced and unbalanced components. By introducing a simple transfor-mation from the state variables to the control variables with a recursive or spectral filter, the conver-gence rate of iteration for minimization of the cost function in 3DVar is greatly accelerated. The defini-tion of dynamical balance depends on the characteristic scale of the circulation considered. The ratio of the balanced to the unbalanced parts is controlled by the prescribed statistics of background errors. Idealized trials produce the same results as the analytic solution. The results of real data case studies show the capability of the system to improve analysis compared to the traditional schemes. Finally, further development of the system is discussed.

  19. Impulsivity in Multiplayer Online Battle Arena Gamers: Preliminary Results on Experimental and Self-Report Measures.

    Science.gov (United States)

    Nuyens, Filip; Deleuze, Jory; Maurage, Pierre; Griffiths, Mark D; Kuss, Daria J; Billieux, Joël

    2016-06-01

    Background and aims Multiplayer Online Battle Arena (MOBA) games have become the most popular type of video games played worldwide, superseding the playing of Massively Multiplayer Online Role-Playing Games and First-Person Shooter games. However, empirical studies focusing on the use and abuse of MOBA games are still very limited, particularly regarding impulsivity, which is an indicator of addictive states but has not yet been explored in MOBA games. In this context, the objective of the present study is to explore the associations between impulsivity and symptoms of addictive use of MOBA games in a sample of highly involved League of Legends (LoL, currently the most popular MOBA game) gamers. Methods Thirty-six LoL gamers were recruited and completed both experimental (Single Key Impulsivity Paradigm) and self-reported impulsivity assessments (s-UPPS-P Impulsive Behavior Scale, Barratt Impulsiveness Scale), in addition to an assessment of problematic video game use (Problematic Online Gaming Questionnaire). Results Results showed links between impulsivity-related constructs and signs of excessive MOBA game involvement. Findings indicated that impaired ability to postpone rewards in an experimental laboratory task was strongly related to problematic patterns of MOBA game involvement. Although less consistent, several associations were also found between self-reported impulsivity traits and signs of excessive MOBA game involvement. Conclusions Despite these results are preliminary and based upon a small (self-selected) sample, the present study highlights potential psychological factors related to the addictive use of MOBA games. PMID:27156376

  20. The genetic variability of the Podolica cattle breed from the Gargano area. Preliminary results

    Directory of Open Access Journals (Sweden)

    Dario Cianci

    2010-01-01

    Full Text Available The Podolica cattle breed is autochthonous of Southern Italy and denoted by its particular rusticity. This study presents the preliminary results of the genetic characterization of the Podolica breed using DNA STR markers. A total of 20 microsatellite loci were analysed in 79 individuals reared in the Gargano area. Number of polymorphisms, allele fre- quencies, deviations from Hardy-Weinberg proportions, linkage disequilibrium between loci and genetic similarities between animals were calculated. The results showed a high deficiency of heterozygotes, the observed mean of het- erozygosis being 0.449, whereas the expected mean was 0.766. Many markers showed also deviations from the Hardy- Weinberg proportions and significant linkage disequilibrium between loci. However the genetic similarity within the pop- ulation was low (0.281 and the average number of alleles per locus was high (10, representing a high genetic vari- ability. In order to explain these results, a stratification of the breed in sub-populations with a high interior genetic homo- geneity but markedly differentiated one from each other could be hypothesized; this situation probably derived from non- random mating within each herd (consanguinity and from the lack of exchange of genetic material between the herds. A further study is needed on a wider sample and extending the analysis to FAO-ISAG microsatellite panel in order to con- firm this hypothesis. This could eventually provide the information necessary for the correct management of the repro- ductive schemes and for genomic traceability of meat production.

  1. Preliminary results of local earthquake tomography around Bali, Lombok, and Sumbawa regions

    Energy Technology Data Exchange (ETDEWEB)

    Nugraha, Andri Dian, E-mail: nugraha@gf.itb.ac.id; Puspito, Nanang T; Yudistira, Tedi [Global Geophysical Reserach Group, Faculty of Mining and Petroleum Engineering, Institute of Technology Bandung, JlGanesa 10, Bandung, 40132 (Indonesia); Kusnandar, Ridwan; Sakti, Artadi Pria [Meteorological, Climatological, and Geophysical Agency (MCGA) of Indonesian, Jakarta (Indonesia)

    2015-04-24

    Bali, Sumbawa, and Lombok regions are located in active tectonic influence by Indo-Australia plate subducts beneath Sunda plate in southern part and local back-arc thrust in northern part the region. Some active volcanoes also lie from eastern part of Java, Bali, Lombok and Sumbawa regions. Previous studies have conducted subsurface seismic velocity imaging using regional and global earthquake data around the region. In this study, we used P-arrival time from local earthquake networks compiled by MCGA, Indonesia within time periods of 2009 up to 2013 to determine seismic velocity structure and simultaneously hypocenter adjustment by applying seismic tomography inversion method. For the tomographic inversion procedure, we started from 1-D initial velocity structure. We evaluated the resolution of tomography inversion results through checkerboard test and calculating derivative weigh sum. The preliminary results of tomography inversion show fairly clearly high seismic velocity subducting Indo-Australian and low velocity anomaly around volcano regions. The relocated hypocenters seem to cluster around the local fault system such as back-arc thrust fault in northern part of the region and around local fault in Sumbawa regions. Our local earthquake tomography results demonstrated consistent with previous studies and improved the resolution. For future works, we will determine S-wave velocity structure using S-wave arrival time to enhance our understanding of geological processes and for much better interpretation.

  2. 78 FR 21107 - Circular Welded Carbon Steel Pipes and Tubes from Turkey: Preliminary Results of Countervailing...

    Science.gov (United States)

    2013-04-09

    ... Steel Pipes and Tubes from Turkey (Preliminary Decision Memorandum) from Edward C. Yang, Senior Director... 5084: Allocation of Free Land and Purchase of Land for less than Adequate Remuneration (LTAR) F....

  3. 76 FR 65684 - Wooden Bedroom Furniture From the People's Republic of China: Preliminary Results of Antidumping...

    Science.gov (United States)

    2011-10-24

    ... High Grade Furniture Co., Ltd.; Golden Lion International Trading Ltd. Shenzhen New Fudu Furniture Co... International Trade Administration Wooden Bedroom Furniture From the People's Republic of China: Preliminary... Administration, International Trade Administration, Department of Commerce. SUMMARY: The Department of...

  4. Preliminary Results From NASA's Space Solar Power Exploratory Research and Technology Program

    Science.gov (United States)

    Howell, Joe T.; Mankins, John C.

    2000-01-01

    Large solar power satellite (SPS) systems that might provide base load power into terrestrial markets were examined extensively in the 1970s by the US Department of Energy (DOE) and the National Aeronautics and Space Administration (NASA). Following a hiatus of about 15 years, the subject of space solar power (SSP) was reexamined by NASA from 1995-1997 in the "fresh look" study, and during 1998 in an SSP "concept definition study". As a result of these efforts, during 1999-2000, NASA has been conducting the SSP Exploratory Research and Technology (SERT) program. The goal of the SERT activity has been to conduct preliminary strategic technology research and development to enable large, multi-megawatt SSP systems and wireless power transmission (WPT) for government missions and commercial markets (in-space and terrestrial). In pursuing that goal, the SERT: (1) refined and modeled systems approaches for the utilization of SSP concepts and technologies, ranging from the near-term (e.g., for space science, exploration and commercial space applications) to the far-term (e.g., SSP for terrestrial markets), including systems concepts, architectures, technology, infrastructure (e.g. transportation), and economics; (2) conducted technology research, development and demonstration activities to produce "proof-of-concept" validation of critical SSP elements for both nearer and farther-term applications; and (3) engendered the beginnings of partnerships (nationally and internationally) that could be expanded, as appropriate, to pursue later SSP technology and applications. Through these efforts, the SERT should allow better informed future decisions regarding further SSP and related technology research and development investments by both NASA and prospective partners, and guide further definition of technology roadmaps - including performance objectives, resources and schedules, as well as "multi-purpose" applications (e.g., commerce, science, and government). This paper

  5. MicroRNAs in Breast Cancer -Our Initial Results.

    Science.gov (United States)

    Popovska-Jankovic, K; Noveski, P; Chakalova, L; Petrusevska, G; Kubelka, K; Plaseska-Karanfilska, D

    2012-12-01

    MicroRNAs (miRNAs) are small [∼21 nucleotide (nt)] non coding RNAs (ncRNAs) that regulate gene expression posttranscriptionally. About 3.0% of human genes encode for miRNAs, and up to 30.0% of human protein coding genes may be regulated by miRNAs. Currently, more than 2000 unique human mature microRNAs are known. MicroRNAs play a key role in diverse biological processes including development, cell proliferation, differentiation and apoptosis. These processes are commonly dysregulated in cancer, implicating miRNAs in carcinogenesis, where they act as tumor supressors or oncogenes. Several miRNAs are associated with breast cancer. Here we present our initial results of miRNA analyses of breast cancer tissues using quantitative real time-polymerase chain reaction (ReTi-PCR) (qPCR) involving stem-loop reverse transcriptase (RT) primers combined with TaqMan® PCR and miRNA microarray analysis.

  6. Biological image construction by using Raman radiation and Pca: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Martinez E, J. C. [IPN, Unidad Profesional Interdisciplinaria de Ingenieria, Campus Guanajuato, Av. Mineral de Valenciana 200, Col. Fracc. Industrial Puerto Interior, 36275 Silao, Guanajuato (Mexico); Cordova F, T. [Universidad de Guanajuato, DIC, Departamento de Ingenieria Fisica, Loma del Bosque No. 103, Col. Lomas del Campestre, 37150 Leon, Guanajuato (Mexico); Hugo R, V., E-mail: jcmartineze@ipn.mx [Universidad de Guadalajara, Centro Universitario de Tonala, Morelos No. 180, 69584 Tonala, Jalisco (Mexico)

    2015-10-15

    Full text: In the last years, the Raman spectroscopy (Rs) technique has had some applications in the study and analysis of biological samples, due to it is able to detect concentrations or presence of certain organic and inorganic compounds of medical interest. In this work, raw data were obtained through measurements in selected points on a square regions in order to detect specific organic / inorganic compounds on biological samples. Gold nano stars samples were prepared and coated with membrane markers (CD 10+ and CD 19+) and diluted in leukemic B lymphocytes. Each data block was evaluated independently by the method of principal component analysis (Pca) in order to find representative dimensionless values (Cp) for each Raman spectrum in a specific coordinate. Each Cp was normalized in a range of 0-255 in order to generate a representative image of 8 bits of the region under study. Data acquisition was performed with Raman microscopy system Renishaw in Via in the range of 550 to 1700 cm-1 with a 785 nm laser source, with a power of 17 m W and 15 s of exposure time were used for each spectrum. In preliminary results could detect the presence of molecular markers CD 10+ and CD 19+ with gold nano stars and discrimination between both markers. The results suggest conducting studies with specific concentrations organic and inorganic materials. (Author)

  7. Holocene evolution and sedimentation rate of Alikes Lagoon, Zakynthos island, Western Greece: preliminary results

    Science.gov (United States)

    Avramidis, P.; Kontopoulos, N.

    2009-07-01

    In the present study we present preliminary results from Alikes lagoon in Zakynthos island, an area that is one of the most seismically active regions of Greece. In order to estimate - interpret the Holocene evolution of the area and to reconstruct the palaeoenvironmental changes, we based on data derived from a 21 m sediment core. Sediment types, structure, colour, as well as contact depths and bed characteristics were recorded in the field. Standarised sedimentological analysis was carried out, on 46 samples including grain size analysis, calculation of moment measures, and micro- and molluscan fossils of 17 selected samples. Moreover, radiocarbon age determinations have been made on individual Cardium shells from two horizons and whole - core Magnetic Susceptibility (MS) measurements were taken. The interpretation of depositional environments suggests a coastal environment (restricted-shallow) with reduced salinity such as a lagoon margin and in a tidal flat and/or marsh particularly. The maximum age of the studied sediments is about 8500 BP. The rate of sedimentation between 8280 BP while 5590 BP was 5.3 mm/yr and between 5590 BP and modern times is on the order of 1.03 mm/yr. These sedimentation rates results are similar to other coastal areas of western Greece.

  8. Holocene evolution and sedimentation rate of Alikes Lagoon, Zakynthos island, Western Greece - preliminary results

    Science.gov (United States)

    Avramidis, P.; Kontopoulos, N.

    2009-03-01

    In the present study we present preliminary results of Zakynthos Alikes lagoon, which is one of the most seismically active regions of Greece. In order to estimate - interpret the Holocene evolution of the area and to reconstruct the palaeonvironmental changes, we based on the data of a 21 m sediment core. Sediment types, structure, colour, as well as contact depths and bed characteristics, were recorded in the field. Standarised sedimentological analysis were carried out, on 46 samples including grain size analysis, calculation of moment measures, and micro- and molluscan fossils of 17 selected samples. Moreover, radiocarbon age determinations have been made on individual Cardium shells from two horizons and whole - core Magnetic Susceptibility (MS) measurements were taken. The interpretation of depositional environments suggests a coastal environment (restricted-shallow) with reduced salinity such as a lagoon margin and in a tidal flat and/or marsh particularly. The maximum age of the study sediments is about 8500 BP. The rate of sedimentation between 8280 BP and 5590 BP was 5.3 mm/yr and between 5590 BP and modern times 1.03 mm/yr. The rate of sedimentation was higher until mid-Holocene while decrease after to 1.03 mm/yr, results which are similar to other coastal areas of western Greece.

  9. Preliminary Results from the PrimEx-II experiment at Jefferson Lab

    Energy Technology Data Exchange (ETDEWEB)

    Gasparian, Ashot [NCA& T, Greensboro, NC; Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

    2016-06-01

    Properties of the neutral pion, as the lightest hadron in Nature, are most sensitive to the basic symmetries and their partial breaking effects in the theory of the strong interaction (QCD). In particular, the po →gg decay width is primarily defined by the spontaneous chiral symmetry breaking effect (chiral anomaly) in QCD. The next order corrections to the anomaly have been shown to be small and are known to a 1% precision level. The PrimEx Collaboration at JLab has developed and performed two Primakoff type experiments to measure the po →gg decay width with a similar precision. The published result from the PrimEx-I experiment, G(p0 →gg ) = 7.82±0.14 (stat.)±0.17 (syst.) eV, was a factor of two more precise than the average value quoted in PDG-2010 [1]. The second experiment was performed in 2010 with a goal of 1.4% total uncertainty to address the next-to-leading-order theory calculations. The preliminary results from the PrimEx-II experiment are presented and discussed in this note.

  10. Preliminary experimental results of tungsten wire-array Z-pinches on primary test stand

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Xian-Bin; Zhou, Shao-Tong; Dan, Jia-Kun; Ren, Xiao-Dong, E-mail: amosrxd@163.com; Wang, Kun-Lun; Zhang, Si-Qun; Li, Jing; Xu, Qiang; Cai, Hong-Chun; Duan, Shu-Chao; Ouyang, Kai; Chen, Guang-Hua; Ji, Ce; Wei, Bing; Feng, Shu-Ping; Wang, Meng; Xie, Wei-Ping; Deng, Jian-Jun [Key Laboratory of Pulsed Power, Institute of Fluid Physics, China Academy of Engineering Physics, P.O. Box 919-108, Mianyang, Sichuan 621999 (China); Zhou, Xiu-Wen; Yang, Yi [Research Center of Laser Fusion, China Academy of Engineering Physics, P.O. Box 919-987, Mianyang, Sichuan 621999 (China)

    2015-07-15

    The Primary Test Stand (PTS) developed at the China Academy of Engineering Physics is a 20 TW pulsed power driver, which can deliver a ∼10 MA, 70 ns rise-time (10%–90%) current to a short-circuit load and has important applications in Z-pinch driven inertial confinement fusion and high energy density physics. Preliminary results of tungsten wire-array Z-pinch experiments on PTS are presented. The load geometries investigated include 15-mm-tall cylindrical single and nested arrays with diameter ranging from 13 mm to 30 mm, consisting of 132–300 tungsten wires with 5–10 μm in diameter. Multiple diagnostics were fielded to characterize the x-ray radiation from wire-array Z pinches. The x-ray peak power (∼50 TW) and total radiated energy (∼500 kJ) were obtained from a single 20-mm-diam array with 80-ns stagnation time. The highest x-ray peak power up to 80 TW with 2.4 ns FWHM was achieved by using a nested array with 20-mm outer diameter, and the total x-ray energy from the nested array is comparable to that of single array. Implosion velocity estimated from the time-resolved image measurement exceeds 30 cm/μs. The detailed experimental results and other findings are presented and discussed.

  11. Cyberknife Stereotactic Body Radiation Therapy for Nonresectable Tumors of the Liver: Preliminary Results

    Directory of Open Access Journals (Sweden)

    K. Goyal

    2010-01-01

    Full Text Available Purpose. Stereotactic body radiation therapy (SBRT has emerged as a treatment option for local tumor control of primary and secondary malignancies of the liver. We report on our updated experience with SBRT in patients with non-resectable tumors of the liver. Methods. Our first 17 consecutive patients (mean age 58.1 years receiving SBRT for HCC (=6, IHC (=3, and LM (=8 are presented. Mean radiation dose was 34Gy delivered over 1–3 fractions. Results. Treated patients had a mean decrease in maximum pretreatment tumor diameter from 6.9±4.6 cm to 5.0±2.1 cm at three months after treatment (<.05. The mean total tumor volume reduction was 44% at six months (<.05. 82% of all patients (14/17 achieved local control with a median follow-up of 8 months. 100% of patients with HCC (=6 achieved local control. Patients with surgically placed fiducial markers had no complications related to marker placement. Conclusion. Our preliminary results showed that SBRT is a safe and effective local treatment modality in selected patients with liver malignancies with minimal adverse events. Further studies are needed to define its role in the management of these malignancies.

  12. Experimental Impeller Fragmentation of Iliocaval Thrombosis Under Tulip Filter Protection: Preliminary Results

    International Nuclear Information System (INIS)

    Purpose: To assess the efficacy of catheter fragmentation of massive caval thrombosis and of filter protection against procedure-related pulmonary embolism. Methods: In 10 sheep, a self-expanding tulip-shaped filter made from Wallstent mesh (diameter 25 mm) was introduced from the right jugular approach into the proximal inferior vena cava. Experimentally induced massive iliocaval thrombosis was fragmented by an impeller catheter (expanded diameter 14 mm), which was advanced coaxially through the sheath of the expanded filter. Post-procedural cavography and pulmonary angiography were performed to document the extent of caval recanalization and pulmonary embolism. Results: In all cases, impeller fragmentation cleared the inferior vena cava and the iliac veins of thrombi completely. Fragments washed downstream were trapped in the filter. In two of the first cases, parts of the clots caused pulmonary embolism before the filter was in place. Further events were avoided by a modification of the experimental setup. Except for some small peripheral perfusion defects in two cases, pulmonary angiograms did not show any incidence of pulmonary embolism. Conclusion: Our preliminary results suggest that impeller fragmentation of iliocaval thrombi under tulip filter protection is effective and does not cause significant pulmonary embolism

  13. PRELIMINARY RESULTS OF BOWL TRAPPING BEES (HYMENOPTERA, APOIDEA IN A SOUTHERN BRAZIL FOREST FRAGMENT

    Directory of Open Access Journals (Sweden)

    Rodrigo B. Gonçalves

    2013-05-01

    Full Text Available In recent years bowl traps have gained attention as a useful method for sampling bees and are now commonly used across the world for this purpose. However, specific questions about the method itself have not yet been tested on different regions of the globe. We present the preliminary results of bowl trapping in a Semidecidual Seasonal forest fragment in southern Brazil, including the test of two different color bowls, two different habitats, and the interaction of these variables in bee species number and composition. We used blue and yellow bowls in the border and in the core trails of the forest fragment. In five sampling days between October to December bowl traps captured 745 specimens of 37 morphospecies, with Halictinae bees being the richest and most abundant group. Non parametrical statistical analyses suggested that different colors of bowl traps influenced bee richness and composition and thus, they should be used together for a more complete sampling. Different trails influenced only the composition, while the interaction with different colors did not have a significant effect. These results, as well as the higher taxonomic composition of the inventoried bees, are similar to other studies reported in the literature.

  14. Preliminary test results from the CELSS Test Facility Engineering Development Unit

    Science.gov (United States)

    Kliss, Mark H.; Macelroy, R. D.; Blackwell, C. C.; Borchers, B. A.; Drews, M. E.; Longabaugh, J. R.; Yendler, B. S.; Zografos, A. I.

    1994-01-01

    As part of the NASA Controlled Ecological Life Support System (CELSS) Program, a CELSS Test Facility (CTF) is being planned for installation on the Space Station. The CTF will be used to provide data on the productivity and efficiency of a variety of CELSS higher plant crops grown in the microgravity environment of the Space Station. Tight environmental control will be maintained while data on gas exchange rates and biomass accumulation rates are collected. In order to obtain an early realistic determination of the subsystem and system requirements necessary to provide the environmental conditions specified for CTF crop productivity experiments, an Engineering Development Unit (EDU) has been designed, constructed and is in the process of subsystem and system testing at NASA Ames Research Center. The EDU is a ground test-bed which will be used to characterize the integrated performance of major subsystem technologies, to evaluate hardware candidates and control strategies required for the CTF, and to further define the ability to meet CTF requirements within present Space Station constraints. This paper reviews the functional requirements for the EDU, and focuses on the performance evaluation and test results of the various subsystems. Preliminary integrated performance results and control system operation are addressed, and plans for future science and technology testing are discussed.

  15. Systematic Search of the Nearest Stars for Exoplanetary Radio Emission: Preliminary results from LOFAR

    Science.gov (United States)

    Winterhalter, Daniel; Knapp, Mary

    2016-04-01

    Radio observations have been used as a tool to search for exoplanets since before the confirmed discovery of the first extrasolar planet. To date, neither targeted observations of known exoplanets nor surveys have produced definitive detections of exoplanetary radio emission. We present the framework for, and initial results from, a blind radio survey of the nearest star systems for exoplanetary radio emission. The very closest stars were chosen to minimize the dilution of potential radio signals by distance and thereby increase the probability of a detection. The goal of this survey is to obtain, at minimum, physically meaningful upper limits on radio emission from (or modulated by) substellar companions of the nearest stars. The target selection criteria for this survey are restricted to distance, observability for LOFAR and the VLA, and data quality metrics only. Stellar properties are not considered because preconceptions about the types of systems most likely to exhibit radio emission have not been observationally confirmed and may be incorrect. Two survey targets, GJ 411 and GJ 725A/B, have been observed with the LOFAR telescope LBA (30-75 MHz) system. A series of 4 2-hour integrations and 1 3-hour integration were made for each target of a period of approximately 2 weeks. Additional observations are underway with LOFAR as well as the VLA. Preliminary results from the first LOFAR observations are presented.

  16. Holocene evolution and sedimentation rate of Alikes Lagoon, Zakynthos island, Western Greece – preliminary results

    Directory of Open Access Journals (Sweden)

    P. Avramidis

    2009-03-01

    Full Text Available In the present study we present preliminary results of Zakynthos Alikes lagoon, which is one of the most seismically active regions of Greece. In order to estimate – interpret the Holocene evolution of the area and to reconstruct the palaeonvironmental changes, we based on the data of a 21 m sediment core. Sediment types, structure, colour, as well as contact depths and bed characteristics, were recorded in the field. Standarised sedimentological analysis were carried out, on 46 samples including grain size analysis, calculation of moment measures, and micro- and molluscan fossils of 17 selected samples. Moreover, radiocarbon age determinations have been made on individual Cardium shells from two horizons and whole – core Magnetic Susceptibility (MS measurements were taken. The interpretation of depositional environments suggests a coastal environment (restricted-shallow with reduced salinity such as a lagoon margin and in a tidal flat and/or marsh particularly. The maximum age of the study sediments is about 8500 BP. The rate of sedimentation between 8280 BP and 5590 BP was 5.3 mm/yr and between 5590 BP and modern times 1.03 mm/yr. The rate of sedimentation was higher until mid-Holocene while decrease after to 1.03 mm/yr, results which are similar to other coastal areas of western Greece.

  17. Application of a PCR method for the diagnosis of ulcerative enteritis: preliminary results

    Directory of Open Access Journals (Sweden)

    Fabrizio Agnoletti

    2010-01-01

    Full Text Available Ulcerative enteritis or “quail disease” is an acute clostridial infection of young birds reported in many avian species, chicken and turkey included. Clostridium colinum is the causative agent of ulcerative enteritis and because of the difficulties bound to the isolation and identification of this bacterium by means of classic bacteriological techniques, its detection appears very hard and the prevalence of this disease could be underestimated. To investigate the diffusion of C. colinum in enteric disease of birds, a recently developed PCR protocol was applied to 42 cultural broths previously inoculated with organs and intestinal samples collected from diseased subjects. PCR-positive broths were cultivated to attempt the isolation of C. colinum. Samples collected from positive birds were subjected to histological examinations. 4 birds (3 broilers chickens and 1 pigeon resulted PCR-positive and, in one case, C. colinum was isolated. Gross and histological lesions of positive birds were compatible with those described in other ulcerative enteritis outbreaks. These preliminary results demonstrates that C. colinum is sporadically implicated in enteric diseases of broiler chickens (14.2%. In addition, the PCR assay proved to be an useful and reliable instrument to support the diagnosis of ulcerative enteritis and to facilitate the isolation of C. colinum.

  18. Connecting the disconnected: Preliminary results and lessons learned from a telepsychology initiative with special management inmates.

    Science.gov (United States)

    Batastini, Ashley B; Morgan, Robert D

    2016-08-01

    The use of telepsychology, such as videoconferencing (VC) systems, has been rapidly increasing as a tool for the provision of mental health services to underserved clients in difficult to access settings. Inmates detained in restrictive housing appear to be at an increased risk of experiencing emotional and behavioral disturbances compared to their general population counterparts, yet they are less likely to receive appropriate treatment due to security constraints. The primary purpose of this article is to describe the process of implementing a novel telepsychology intervention specifically designed to offer group therapy to high-security, administratively segregated inmates. In addition, preliminary results on treatment and therapeutic process outcomes in a sample of 49 participants are reported. Although some evidence indicated that telepsychology was less preferred than in-person sessions, group differences on measures of psychological functioning and criminal thinking were not found across 3 conditions (telepsychology, in-person, and a no-treatment control). Furthermore, a number of limitations associated with program implementation and study design suggest that results be interpreted with caution and should not be used to discount the use of telepsychology as a viable treatment delivery option. Recommendations for future development and evaluation of telepsychological programs are discussed within the context of correctional settings and beyond. (PsycINFO Database Record PMID:27504646

  19. [A new locking nail for proximal humerus fractures: the Telegraph nail, technique and preliminary results].

    Science.gov (United States)

    Cuny, C; Pfeffer, F; Irrazi, M; Chammas, M; Empereur, F; Berrichi, A; Metais, P; Beau, P

    2002-02-01

    We present a new nail, the telegraph nail, designed for the treatment of proximal fractures of the humerus. This nail has a new locking system providing a self-stabilization of the cancelous screws inserted in small fragments. We discuss the surgical technique and present preliminary results. The anterolateral approach and nail insertion through the medial and well vascularized part of the cuff is described for simple fractures. With the cup and ball technique, this nail can also be used for complex fractures of the proximal humerus with three or four fragments and major displacement. With this method, the nail is inserted before reduction and locked in the distal humerus before fixation of the head and tuberosities around the head once the targeting device removed. We report results for the first 64 nails inserted in our unit during the first year (1998-1999). Outcome was assessed at 11 months mean follow-up using the Constant score. Outcome was favorable, including in patients with complex fractures involving 3 or 4 separate displaced fragments. Besides providing an anatomically stable reconstruction, the telegraph nail has the advantage of allowing early mobilization of the shoulder joint. This method is a useful alternative to prosthetic reconstruction for traumatic fractures of the proximal humerus. PMID:11973536

  20. Preliminary results of a national quality audit programme in radiotherapy services in Cuba

    International Nuclear Information System (INIS)

    The current state of radiotherapy in Cuba has allowed to pass to a superior stage in the process of quality assurance, the establishment of a National Quality Audit Program (PNAC). The National Control Center for Medical Devices, as national regulator entity for the control and supervision of the medical devices of the National Health System, is responsible for the implementation of this program. This paper presents the preliminary results of the execution of the PNAC in teletherapy services with isotopic units of 60Co. The audits were carried out according to the methodology settled down in the normalized procedure of operation of the PNAC. The physical aspects related with the treatment were audited, such as: the installation and unit's safety, mechanical and dosimetric aspects of the treatment unit and organizational aspects of the institution quality assurance program. Also carried out, in the clinical aspect, verifications of cases type planned by the qualified personnel of the service. The results corresponding to the determination of the reference dose for each institution were compared with those obtained in a postal audit with the International Atomic Energy Agency. These first audits allowed to evaluate the performance of the institutions' program of quality assurance and a feedback for the setting about to the PNAC. (author)

  1. Preliminary experimental results of tungsten wire-array Z-pinches on primary test stand

    International Nuclear Information System (INIS)

    The Primary Test Stand (PTS) developed at the China Academy of Engineering Physics is a 20 TW pulsed power driver, which can deliver a ∼10 MA, 70 ns rise-time (10%–90%) current to a short-circuit load and has important applications in Z-pinch driven inertial confinement fusion and high energy density physics. Preliminary results of tungsten wire-array Z-pinch experiments on PTS are presented. The load geometries investigated include 15-mm-tall cylindrical single and nested arrays with diameter ranging from 13 mm to 30 mm, consisting of 132–300 tungsten wires with 5–10 μm in diameter. Multiple diagnostics were fielded to characterize the x-ray radiation from wire-array Z pinches. The x-ray peak power (∼50 TW) and total radiated energy (∼500 kJ) were obtained from a single 20-mm-diam array with 80-ns stagnation time. The highest x-ray peak power up to 80 TW with 2.4 ns FWHM was achieved by using a nested array with 20-mm outer diameter, and the total x-ray energy from the nested array is comparable to that of single array. Implosion velocity estimated from the time-resolved image measurement exceeds 30 cm/μs. The detailed experimental results and other findings are presented and discussed

  2. A Morphing Technique Applied to Lung Motions in Radiotherapy: Preliminary Results

    Directory of Open Access Journals (Sweden)

    R. Laurent

    2010-01-01

    Full Text Available Organ motion leads to dosimetric uncertainties during a patient’s treatment. Much work has been done to quantify the dosimetric effects of lung movement during radiation treatment. There is a particular need for a good description and prediction of organ motion. To describe lung motion more precisely, we have examined the possibility of using a computer technique: a morphing algorithm. Morphing is an iterative method which consists of blending one image into another image. To evaluate the use of morphing, Four Dimensions Computed Tomography (4DCT acquisition of a patient was performed. The lungs were automatically segmented for different phases, and morphing was performed using the end-inspiration and the end-expiration phase scans only. Intermediate morphing files were compared with 4DCT intermediate images. The results showed good agreement between morphing images and 4DCT images: fewer than 2 % of the 512 by 256 voxels were wrongly classified as belonging/not belonging to a lung section. This paper presents preliminary results, and our morphing algorithm needs improvement. We can infer that morphing offers considerable advantages in terms of radiation protection of the patient during the diagnosis phase, handling of artifacts, definition of organ contours and description of organ motion.

  3. The Results of Postoperative Radiation Therapy in the Rectal Cancer

    International Nuclear Information System (INIS)

    Purpose: Despite apparently complete resection of cancer of the rectum, local recurrence rate was high. Radiation therapy has been used either alone or in combination with chemotherapy as an adjunct to surgery to reduce the risk of recurrence. This study was designed to evaluate the prognostic factors, survival rate and local recurrence rate of the rectal cancer who had received postoperative radiation therapy by retrospective analysis. Method: From 1982 to 1990, 63 patients with cancer of the rectum surgically staged as B2 or C disease received postoperative adjuvant radiation therapy after curative resection of tumor for cure. Postoperative radiation therapy was given to the whole pelvis (mean dose: 5040 cGy in 5-6weeks) and perineum was included in irradiated field in case of abdominoperineal resection. Results: Three-year actuarial survival rate was 73.2% overall, 87.7% in stage B2+3 and 62.9% in stage C2+3. Three-year disease-free survival rate was 69.5% overall, 87.7% in stage B2+3 and 56.8% in stage C2+3. Three-year disease-free survival rate in anterior resection was 77.8% and 44.4% in abdominoperineal resection. The local recurrence rate was 15.9% and distant failure rate was 20.6%. Severe late complication was small bowel obstruction in 6 patients and surgery was required in 4 patients (6.3%). The prognostic factors were stage (p=0.0221) and method of surgery(p=0.0414) (anterior resection vs abdominoperineal resection). Conclusion: This study provides evidence supporting the use of postoperative radiation therapy for reducing the local recurrence rate in patients who have had curative resection of rectal cancer with involvement of perirectal fat or regional nodes or both (stage B2 and C)

  4. The Results of Postoperative Radiation Therapy in the Rectal Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyung Ja [Ewha Womans University College of Medicine, Seoul (Korea, Republic of)

    1994-02-15

    Purpose: Despite apparently complete resection of cancer of the rectum, local recurrence rate was high. Radiation therapy has been used either alone or in combination with chemotherapy as an adjunct to surgery to reduce the risk of recurrence. This study was designed to evaluate the prognostic factors, survival rate and local recurrence rate of the rectal cancer who had received postoperative radiation therapy by retrospective analysis. Method: From 1982 to 1990, 63 patients with cancer of the rectum surgically staged as B2 or C disease received postoperative adjuvant radiation therapy after curative resection of tumor for cure. Postoperative radiation therapy was given to the whole pelvis (mean dose: 5040 cGy in 5-6weeks) and perineum was included in irradiated field in case of abdominoperineal resection. Results: Three-year actuarial survival rate was 73.2% overall, 87.7% in stage B2+3 and 62.9% in stage C2+3. Three-year disease-free survival rate was 69.5% overall, 87.7% in stage B2+3 and 56.8% in stage C2+3. Three-year disease-free survival rate in anterior resection was 77.8% and 44.4% in abdominoperineal resection. The local recurrence rate was 15.9% and distant failure rate was 20.6%. Severe late complication was small bowel obstruction in 6 patients and surgery was required in 4 patients (6.3%). The prognostic factors were stage (p=0.0221) and method of surgery(p=0.0414) (anterior resection vs abdominoperineal resection). Conclusion: This study provides evidence supporting the use of postoperative radiation therapy for reducing the local recurrence rate in patients who have had curative resection of rectal cancer with involvement of perirectal fat or regional nodes or both (stage B2 and C)

  5. Integrated Bio-ISRU and Life Support Systems at the Lunar Outpost: Concept and Preliminary Results

    Science.gov (United States)

    Brown, I. I.; Garrison, D. H.; Allen, C. C.; Pickering, K.; Sarkisova, S. A.; Galindo, C., Jr.; Pan, D.; Foraker, E.; Mckay, D. S.

    2009-01-01

    We continue the development of our concept of a biotechnological loop for in-situ resource extraction along with propellant and food production at a future lunar outpost, based on the cultivation of litholytic cyanobacteria (LCB) with lunar regolith (LR) in a geobioreactor energized by sunlight. Our preliminary studies have shown that phototropic cultivation of LCB with simulants of LR in a low-mineralized medium supplemented with CO2 leads to rock dissolution (bioweathering) with the resulting accumulation of Fe, Mg and Al in cyanobacterial cells and in the medium. LCB cultivated with LR simulants produces more O2 than the same organisms cultivated in a high-mineralized medium. The loss of rock mass after bioweathering with LCB suggests the release of O from regolith. Further studies of chemical pathways of released O are required. The bioweathering process is limited by the availability of CO2, N, and P. Since lunar regolith is mainly composed of O, Si, Ca, Al and Mg, we propose to use organic waste to supply a geobioreactor with C, N and P. The recycling of organic waste, including urine, through a geobioreactor will allow for efficient element extraction as well as oxygen and biomass production. The most critical conclusion is that a biological life support system tied to a geobioreactor might be more efficient for supporting an extraterrestrial outpost than a closed environmental system.

  6. Post-impact climate conditions on early Mars: preliminary results from GCM simulations

    Science.gov (United States)

    Steakley, Kathryn; Murphy, Jim; Kahre, Melinda A.; Haberle, Robert

    2016-10-01

    Observations imply that liquid water was stable on Mars' surface during the late Noachian/early Hesperian era, with valley networks forming roughly 3.5-3.75 billion years ago, possibly from precipitation and runoff (Fassett & Head 2008, Icarus 195, 61; Hynek et al., 2010, JGR Planets, 115, E09008). Climate models, however, struggle to reproduce such warm conditions (Forget et al., 2013, Icarus 21, 81). Volcanism and impacts have been suggested as mechanisms of either inducing a warm and wet environment or causing local melting in a cold and wet environment. Comets and asteroids are capable of injecting into the atmosphere both kinetic energy from the impact and water from the object itself and from vaporized surface and subsurface ice. Segura et al. (2008, JGR Planets 113, E11007) find using a 1-D atmospheric model that significant rainfall and periods of above-freezing temperatures lasting months to years can follow impacts of objects between 30 and 100 km in diameter. We revisit this work utilizing a 3-D global climate model (GCM) to consider the effects of dynamics, topography, global surface ice variations, etc. We present preliminary results from the NASA ARC Mars GCM investigating global temperature and precipitation behavior in a post-impact, early Mars environment.

  7. The Geoengineering Model Intercomparison Project Phase 6 (GeoMIP6: simulation design and preliminary results

    Directory of Open Access Journals (Sweden)

    B. Kravitz

    2015-10-01

    Full Text Available We present a suite of new climate model experiment designs for the Geoengineering Model Intercomparison Project (GeoMIP. This set of experiments, named GeoMIP6 (to be consistent with the Coupled Model Intercomparison Project Phase 6, builds on the previous GeoMIP project simulations, and has been expanded to address several further important topics, including key uncertainties in extreme events, the use of geoengineering as part of a portfolio of responses to climate change, and the relatively new idea of cirrus cloud thinning to allow more longwave radiation to escape to space. We discuss experiment designs, as well as the rationale for those designs, showing preliminary results from individual models when available. We also introduce a new feature, called the GeoMIP Testbed, which provides a platform for simulations that will be performed with a few models and subsequently assessed to determine whether the proposed experiment designs will be adopted as core (Tier 1 GeoMIP experiments. This is meant to encourage various stakeholders to propose new targeted experiments that address their key open science questions, with the goal of making GeoMIP more relevant to a broader set of communities.

  8. The Geoengineering Model Intercomparison Project Phase 6 (GeoMIP6): simulation design and preliminary results

    Science.gov (United States)

    Kravitz, B.; Robock, A.; Tilmes, S.; Boucher, O.; English, J. M.; Irvine, P. J.; Jones, A.; Lawrence, M. G.; MacCracken, M.; Muri, H.; Moore, J. C.; Niemeier, U.; Phipps, S. J.; Sillmann, J.; Storelvmo, T.; Wang, H.; Watanabe, S.

    2015-10-01

    We present a suite of new climate model experiment designs for the Geoengineering Model Intercomparison Project (GeoMIP). This set of experiments, named GeoMIP6 (to be consistent with the Coupled Model Intercomparison Project Phase 6), builds on the previous GeoMIP project simulations, and has been expanded to address several further important topics, including key uncertainties in extreme events, the use of geoengineering as part of a portfolio of responses to climate change, and the relatively new idea of cirrus cloud thinning to allow more longwave radiation to escape to space. We discuss experiment designs, as well as the rationale for those designs, showing preliminary results from individual models when available. We also introduce a new feature, called the GeoMIP Testbed, which provides a platform for simulations that will be performed with a few models and subsequently assessed to determine whether the proposed experiment designs will be adopted as core (Tier 1) GeoMIP experiments. This is meant to encourage various stakeholders to propose new targeted experiments that address their key open science questions, with the goal of making GeoMIP more relevant to a broader set of communities.

  9. Observation of seismicity based on DOMERAPI and BMKG seismic networks: A preliminary result from DOMERAPI project

    Science.gov (United States)

    Ramdhan, Mohamad; Nugraha, Andri Dian; Widiyantoro, Sri; Kristyawan, Said; Sembiring, Andry Syaly; Mtaxian, Jean-Philippe

    2016-05-01

    DOMERAPI project has involved earth scientists from Indonesia and France to conduct comprehensively a study of the internal structure of Mt. Merapi and its vicinity based on seismic tomographic imaging. The DOMERAPI seismic network was running from October 2013 to April 2015 consisting of 53 broad-band seismometers, covering Mt. Merapi and Mt. Merbabu, and some geological features such as Opak and Dengkeng faults. Earthquake hypocenter determination conducted in this study is an important step before seismic tomographic imaging. The earthquake events were identified and picked manually and carefully. The majority of earthquakes occured outside the DOMERAPI network. The ray paths of seismic waves from these earthquakes passed through the deep part of the study area around Merapi. The joint data of BMKG and DOMERAPI networks can minimize the azimuthal gap, which is often used to obtain an indication of the reliability of the epicentral solution. Our preliminary results show 279 events from October 2013 to mid August 2014. For future work, we will incorporate the BPPTKG (Center for Research and Technology Development of Geological Disaster) data catalogue in order to enrich seismic ray paths. The combined data catalogues will provide information as input for further advanced studies and volcano hazards mitigation.

  10. Extraction of metals from automotive shredder residue:Preliminary results of different leaching systems

    Institute of Scientific and Technical Information of China (English)

    Francesco Ferella; Ida De Michelis; Agostino Scocchera; Mario Pelino; Francesco Vegliò

    2015-01-01

    The study is focused on the extraction of valuable metals from automotive shredder residue (ASR) by different leaching solutions. First, ASR samples were roasted at 600 °C to simulate a thermal treatment processing. Distil ed water, citric and sulphuric acid were preliminarily investigated, thus two further full factorial systems entailing H2SO4–H2O2 and H2SO4–H2O2–Fe3+ were tested. The preliminary experimental results showed that 0.1 mol·L−1 H2SO4 solution extracted 100%of Cu, Fe and Zn, whereas citric acid leached 100%of Zn and Pb, 59%of Fe and 62%of Cu;whereas, H2SO4–H2O2 and H2SO4–H2O2–Fe3+(Fenton's) leaching media showed that Cu, Fe and Zn can be extracted simultaneously and completely from the ASR ashes before final disposal.

  11. Preliminary Results of Subsurface Exploration and Monitoring at the Johnson Creek Landslide, Lincoln County, Oregon

    Science.gov (United States)

    Schulz, William H.; Ellis, William L.

    2007-01-01

    The Johnson Creek landslide is a translational, primarily bedrock landslide located along the Oregon coast about 5 km north of Newport. The landslide has damaged U.S. Highway 101 many times since construction of the highway and at least two geological and geotechnical investigations of the landslide have been performed by Oregon State agencies. In cooperation with the Oregon Department of Geology and Mineral Industries and the Oregon Department of Transportation, the U.S. Geological Survey upgraded landslide monitoring systems and installed additional monitoring devices at the landslide beginning in 2004. Monitoring devices at the landslide measured landslide displacement, rainfall, air temperature, shallow soil-water content, and ground-water temperature and pressure. The devices were connected to automatic dataloggers and read at one-hour and, more recently, 15-minute intervals. Monitoring results were periodically downloaded from the dataloggers using cellular telemetry. The purposes of this report are to describe and present preliminary monitoring data from November 19, 2004, to March 31, 2007.

  12. Preliminary Paleomagnetic Results From Tertiary Rocks of Sedimentary Basins in Northern Vietnam and Tectonic Implications

    Science.gov (United States)

    Zhao, X.; Liu, Z.; Le, K.; Zhao, Y.; Hoang, V.; Phan, D.

    2013-12-01

    The South China Sea (SCS) is a classical representative of western Pacific marginal seas and contains records of Cenozoic tectonic events of SE Asia. The SCS has been at the center stage of many first-order tectonic and paleoclimatic events since the Mesozoic. One clear way to evaluate the relationship between tectonic uplift and climate is to study the resulting changes in marginal sea strata. To this end, we will conduct an integrated paleomagnetic and stratigraphic investigation on Tertiary strata from Phu Tho and Yen Bai provinces, northern Vietnam to help understand the causal linkages among geological and tectonic events and their consequences related to the SCS evolution. We will collect paleomagnetic samples at sections where the most continuous, complete, and best preserved Eocene-Miocene successions. Standard paleomagnetic field tests, such as the fold, reversal, and conglomerate tests will be used to determine the relative age of the magnetization. In addition to detailed thermal and alternating field demagnetization and analysis, selected samples will also be subjected to several rock magnetic analyses to identify magnetic carriers in the rocks. In particular, the hysteresis parameters Jrs/Js and Hcr /Hc ratios will enable us to apply techniques for detecting low-temperature remagnetization of sedimentary rocks. Preliminary finding of this ongoing project will be presented.

  13. The Geoengineering Model Intercomparison Project Phase 6 (GeoMIP6). Simulation Design and Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Kravitz, Benjamin S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Robock, Alan [Rutgers Univ., New Brunswick, NJ (United States); Tilmes, S. [National Center for Atmospheric Research, Boulder, CO (United States); Boucher, Olivier [Laboratoire de Meteorologie Dynamique, Paris (France); English, J. [NOAA Earth System Research Lab. and Univ. of Colorado, Boulder, CO (United States); Irvine, Peter [Inst. of Advanced Sustainability Studies, Potsdam (Germany); Jones, Andrew [Met Office Hadley Centre, Exeter (United Kingdom); Lawrence, M. G. [Inst. of Advanced Sustainability Studies, Potsdam (Germany); Maccracken, Michael C. [Climate Inst., Washington, DC (United States); Muri, Helene O. [Univ. of Oslo (Norway); Moore, John [Beijing Normal Univ., Beijing (China); Niemeier, Ulrike [Max Planck Inst. for Meterology, Hamburg (Germany); Phipps, Steven [Univ. of New South Wales, Sydney, NSW (Australia); Sillmann, Jana [Center for International Climate and Environmental Research, Oslo (Norway); Storelvmo, Trude [Yale Univ., New Haven, CT (United States); Wang, Hailong [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Watanabe, Shingo [Japan Agency for Marine-Earth Science and Technology, Yokohama (Japan)

    2015-10-27

    We present a suite of new climate model experiment designs for the Geoengineering Model Intercomparison Project (GeoMIP). This set of experiments, named GeoMIP6 (to be consistent with the Coupled Model Intercomparison Project Phase 6), builds on the previous GeoMIP project simulations, and has been expanded to address several further important topics, including key uncertainties in extreme events, the use of geoengineering as part of a portfolio of responses to climate change, and the relatively new idea of cirrus cloud thinning to allow more longwave radiation to escape to space. We discuss experiment designs, as well as the rationale for those designs, showing preliminary results from individual models when available. We also introduce a new feature, called the GeoMIP Testbed, which provides a platform for simulations that will be performed with a few models and subsequently assessed to determine whether the proposed experiment designs will be adopted as core (Tier 1) GeoMIP experiments. This is meant to encourage various stakeholders to propose new targeted experiments that address their key open science questions, with the goal of making GeoMIP more relevant to a broader set of communities.

  14. Climate Change Impact on Hydrological Extremes: Preliminary Results from the Polish-Norwegian Project

    Directory of Open Access Journals (Sweden)

    Romanowicz Renata J

    2016-04-01

    Full Text Available This paper presents the background, objectives, and preliminary outcomes from the first year of activities of the Polish–Norwegian project CHIHE (Climate Change Impact on Hydrological Extremes. The project aims to estimate the influence of climate changes on extreme river flows (low and high and to evaluate the impact on the frequency of occurrence of hydrological extremes. Eight “twinned” catchments in Poland and Norway serve as case studies. We present the procedures of the catchment selection applied in Norway and Poland and a database consisting of near-natural ten Polish and eight Norwegian catchments constructed for the purpose of climate impact assessment. Climate projections for selected catchments are described and compared with observations of temperature and precipitation available for the reference period. Future changes based on those projections are analysed and assessed for two periods, the near future (2021–2050 and the far-future (2071–2100. The results indicate increases in precipitation and temperature in the periods and regions studied both in Poland and Norway.

  15. Climate Change Impact on Hydrological Extremes: Preliminary Results from the Polish-Norwegian Project

    Science.gov (United States)

    Romanowicz, Renata J.; Bogdanowicz, Ewa; Debele, Sisay E.; Doroszkiewicz, Joanna; Hisdal, Hege; Lawrence, Deborah; Meresa, Hadush K.; Napiórkowski, Jarosław J.; Osuch, Marzena; Strupczewski, Witold G.; Wilson, Donna; Wong, Wai Kwok

    2016-04-01

    This paper presents the background, objectives, and preliminary outcomes from the first year of activities of the Polish-Norwegian project CHIHE (Climate Change Impact on Hydrological Extremes). The project aims to estimate the influence of climate changes on extreme river flows (low and high) and to evaluate the impact on the frequency of occurrence of hydrological extremes. Eight "twinned" catchments in Poland and Norway serve as case studies. We present the procedures of the catchment selection applied in Norway and Poland and a database consisting of near-natural ten Polish and eight Norwegian catchments constructed for the purpose of climate impact assessment. Climate projections for selected catchments are described and compared with observations of temperature and precipitation available for the reference period. Future changes based on those projections are analysed and assessed for two periods, the near future (2021-2050) and the far-future (2071-2100). The results indicate increases in precipitation and temperature in the periods and regions studied both in Poland and Norway.

  16. Upper crustal structure beneath East Java from ambient noise tomography: A preliminary result

    International Nuclear Information System (INIS)

    East Java has a fairly complex geological structure. Physiographically East Java can be divided into three zones, i.e. the Southern Mountains zone in the southern part, the Kendeng zone in the middle part, and the Rembang zone in the northern part. Most of the seismic hazards in this region are due to processes in the upper crust. In this study, the Ambient Noise Tomography (ANT) method is used to image the upper crustal structure beneath East Java. We have used seismic waveform data recorded by 8Meteorological, Climatological and Geophysical Agency (BMKG) stationary seismographic stations and 16 portable seismographs installed for 2 to 8 weeks. The data were processed to obtain waveforms fromnoise cross-correlation between pairs of seismographic stations. Our preliminary results indicate that the Kendeng zone, an area of low gravity anomaly, is associated with a low velocity zone. On the other hand, the southern mountain range, which has a high gravity anomaly, is related to a high velocity anomaly as shown by our tomographic images

  17. Preliminary results of the aerosol optical depth retrieval in Johor, Malaysia

    International Nuclear Information System (INIS)

    Monitoring of atmospheric aerosols over the urban area is important as tremendous amounts of pollutants are released by industrial activities and heavy traffic flow. Air quality monitoring by satellite observation provides better spatial coverage, however, detailed aerosol properties retrieval remains a challenge. This is due to the limitation of aerosol retrieval algorithm on high reflectance (bright surface) areas. The aim of this study is to retrieve aerosol optical depth over urban areas of Iskandar Malaysia; the main southern development zone in Johor state, using Moderate Resolution Imaging Spectroradiometer (MODIS) 500 m resolution data. One of the important steps is the aerosol optical depth retrieval is to characterise different types of aerosols in the study area. This information will be used to construct a Look Up Table containing the simulated aerosol reflectance and corresponding aerosol optical depth. Thus, in this study we have characterised different aerosol types in the study area using Aerosol Robotic Network (AERONET) data. These data were processed using cluster analysis and the preliminary results show that the area is consisting of coastal urban (65%), polluted urban (27.5%), dust particles (6%) and heavy pollution (1.5%) aerosols

  18. Preliminary results of the aerosol optical depth retrieval in Johor, Malaysia

    Science.gov (United States)

    Lim, H. Q.; Kanniah, K. D.; Lau, A. M. S.

    2014-02-01

    Monitoring of atmospheric aerosols over the urban area is important as tremendous amounts of pollutants are released by industrial activities and heavy traffic flow. Air quality monitoring by satellite observation provides better spatial coverage, however, detailed aerosol properties retrieval remains a challenge. This is due to the limitation of aerosol retrieval algorithm on high reflectance (bright surface) areas. The aim of this study is to retrieve aerosol optical depth over urban areas of Iskandar Malaysia; the main southern development zone in Johor state, using Moderate Resolution Imaging Spectroradiometer (MODIS) 500 m resolution data. One of the important steps is the aerosol optical depth retrieval is to characterise different types of aerosols in the study area. This information will be used to construct a Look Up Table containing the simulated aerosol reflectance and corresponding aerosol optical depth. Thus, in this study we have characterised different aerosol types in the study area using Aerosol Robotic Network (AERONET) data. These data were processed using cluster analysis and the preliminary results show that the area is consisting of coastal urban (65%), polluted urban (27.5%), dust particles (6%) and heavy pollution (1.5%) aerosols.

  19. Experimental studies in a single-phase parallel channel natural circulation system. Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Bodkha, Kapil; Pilkhwal, D.S.; Jana, S.S.; Vijayan, P.K. [Bhabha Atomic Research Centre, Mumbai (India). Reactor Engineering Div.

    2016-03-15

    Natural circulation systems find extensive applications in industrial engineering systems. One of the applications is in nuclear reactor where the decay heat is removed by natural circulation of the fluid under off-normal conditions. The upcoming reactor designs make use of natural circulation in order to remove the heat from core under normal operating conditions also. These reactors employ multiple vertical fuel channels with provision of on-power refueling/defueling. Natural circulation systems are relatively simple, safe and reliable when compared to forced circulation systems. However, natural circulation systems are prone to encounter flow instabilities which are highly undesirable for various reasons. Presence of parallel channels under natural circulation makes the system more complicated. To examine the behavior of parallel channel system, studies were carried out for single-phase natural circulation flow in a multiple vertical channel system. The objective of the present work is to study the flow behavior of the parallel heated channel system under natural circulation for different operating conditions. Steady state and transient studies have been carried out in a parallel channel natural circulation system with three heated channels. The paper brings out the details of the system considered, different cases analyzed and preliminary results of studies carried out on a single-phase parallel channel system.

  20. Multitemporal Spaceborne SAR Data For Urbanization Monitoring In China: Preliminary Result

    Science.gov (United States)

    Ban, Yifang; Yousif, Osama Adam

    2010-10-01

    The objective of this research is to investigate multitemporal spaceborne SAR data for urbanization monitoring in China. A generalized version of Kittler- Illingworth minimum-error thresholding algorithm, that takes into account the non-Gaussian distribution of SAR images, was tested to automatically classify the change variable derived from SAR multitemporal images into two classes, change and no change. A modified ratio operator was examined for identifying both positive and negative changes by comparing the multitemporal SAR images on a pixel-by-pixel basis. Various probability density functions such as Log normal, Generalized Gaussian, Nakagami ratio, and Weibull ratio models were tested to model the distribution of the change and no change classes. The preliminary results showed that this unsupervised change detection algorithm is very effective in detecting temporal changes in urban areas using multitemporal SAR images. The initial findings indicated that change detection accuracy varies depending on how the assumed conditional class density function fits the histograms of change and no change classes.

  1. The Radii and Oblateness of Pluto and Charon: Preliminary Results from the 2015 New Horizons Flyby

    Science.gov (United States)

    Lisse, Carey M.; Nimmo, Francis; McKinnon, William B.; Umurhan, Orkan M.; Buie, Marc W.; Lauer, Tod R.; Roberts, James H.; Stern, S. Alan; Weaver, Hal A.; Young, Leslie A.; Ennico-Smith, Kimberly; Olkin, Cathy B.

    2015-11-01

    We present preliminary results for the radii and oblateness of Pluto and Charon. Accurate determinations of the mean radii of Pluto and Charon are important for establishing their densities and bulk composition. A fossil bulge, if present, would place constraints on the thermal and orbital evolution of these bodies [1,2]. The New Horizons LORRI imaging system [3] has provided global images of Pluto and Charon, with best resolutions of 3.8 and 2.3 km/pix, respectively. Three separate approaches have been used to determine mean radii and oblateness from the images, two using a threshold DN value [4,5] and one using a maximum gradient method. These approaches were validated using synthetic images having a range of photometric functions. Tradeoffs between the limb center location and the derived shape in individual images can be reduced by combining limb pixel locations obtained from different imaged rotational phases.This work was supported by NASA's New Horizons project.[1] Robuchon & Nimmo, Icarus 216, 426, 2011. [2] McKinnon & Singer, DPS 46, abs. no. 419.07, 2014. [3] Cheng et al., SSR 140, 189, 2008. [4] Dermott & Thomas, Icarus 73, 25, 1988. [5] Thomason & Nimmo, LPSC 46, abs. no. 1462, 2015.

  2. Radii and Shape of Pluto and Charon: Preliminary Results from New Horizons

    Science.gov (United States)

    Nimmo, F.; Lisse, C. M.; Umurhan, O. M.; McKinnon, W. B.; Buie, M. W.; Lauer, T.; Beyer, R. A.; Moore, J. M.; Stern, A.; Weaver, H. A., Jr.; Olkin, C.; Ennico Smith, K.; Young, L. A.; Bierson, C. J.

    2015-12-01

    Accurate determinations of the mean radii of Pluto and Charon are important for establishing their densities and thus bulk composition. A fossil bulge, if present, would place constraints on the thermal and orbital evolution of these bodies [1,2]. The New Horizons LORRI imaging system [3] has provided global images of Pluto and Charon, with best resolutions of 3.8 and 2.3 km/pix, respectively. Three separate approaches have been used to determine mean radii and shape from the images, two using a threshold DN value [4,5] and one using a maximum gradient method. These approaches were validated using synthetic images having a range of photometric functions. Tradeoffs between the limb center location and the derived shape in individual images can be reduced by combining limb picks from different images. Preliminary results for both Pluto and Charon will be presented. [1] Robuchon & Nimmo, Icarus 216, 426, 2011. [2] McKinnon & Singer, DPS 46, abs. no. 419.07, 2014. [3] Cheng et al., SSR 140, 189, 2008. [4] Dermott & Thomas, Icarus 73, 25, 1988. [5] Thomason & Nimmo, LPSC 46, abs. no. 1462, 2015.

  3. Simulating Late Ordovician deep ocean O2 with an earth system climate model. Preliminary results.

    Science.gov (United States)

    D'Amico, Daniel F.; Montenegro, Alvaro

    2016-04-01

    The geological record provides several lines of evidence that point to the occurrence of widespread and long lasting deep ocean anoxia during the Late Ordovician, between about 460-440 million years ago (ma). While a series of potential causes have been proposed, there is still large uncertainty regarding how the low oxygen levels came about. Here we use the University of Victoria Earth System Climate Model (UVic ESCM) with Late Ordovician paleogeography to verify the impacts of paleogeography, bottom topography, nutrient loading and cycling and atmospheric concentrations of O2 and CO2 on deep ocean oxygen concentration during the period of interest. Preliminary results so far are based on 10 simulations (some still ongoing) covering the following parameter space: CO2 concentrations of 2240 to 3780 ppmv (~8x to 13x pre-industrial), atmospheric O2 ranging from 8% to 12% per volume, oceanic PO4 and NO3 loading from present day to double present day, reductions in wind speed of 50% and 30% (winds are provided as a boundary condition in the UVic ESCM). For most simulations the deep ocean remains well ventilated. While simulations with higher CO2, lower atmospheric O2 and greater nutrient loading generate lower oxygen concentration in the deep ocean, bottom anoxia - here defined as concentrations concentrations.

  4. Trajectory planning method for reduced patient risk in image-guided neurosurgery: concept and preliminary results

    Science.gov (United States)

    Shamir, Reuben R.; Joskowicz, Leo; Antiga, Luca; Foroni, Roberto I.; Shoshan, Yigal

    2010-02-01

    We present a new preoperative planning method to quantify and help reduce the risk associated with needle and tool insertion trajectories in image-guided keyhole neurosurgery. The goal is to quantify the risk of a proposed straight trajectory, and/or to find the trajectory with the lowest risk to nearby brain structures based on pre-operative CT/MRI images. The method automatically computes the risk associated with a given trajectory, or finds the trajectory with the lowest risk to nearby brain structures based on preoperative image segmentation and on a risk volume map. The surgeon can revise the suggested trajectory, add a new one using interactive 3D visualization, and obtain a quantitative risk measure. The trajectory risk is evaluated based on the tool placement uncertainty, on the proximity of critical brain structures, and on a predefined table of quantitative geometric risk measures. Our preliminary results on a clinical dataset with eight targets show a significant reduction in trajectory risk and a shortening of the preoperative planning time as compared to the conventional method.

  5. Upper crustal structure beneath East Java from ambient noise tomography: A preliminary result

    Energy Technology Data Exchange (ETDEWEB)

    Martha, Agustya Adi [Meteorological, Climatological and Geophysical Agency, Jakarta (Indonesia); Graduate Research on Earthquakes and Active Tectonics, Institut Teknologi Bandung, Bandung (Indonesia); Widiyantoro, Sri [Global Geophysics Group, Institut Teknologi Bandung, Bandung (Indonesia); Center for Disaster Mitigation, Institut Teknologi Bandung, Bandung (Indonesia); Cummins, Phil; Saygin, Erdinc [Research School of Earth Sciences, Australian National University, Canberra (Australia); Masturyono [Meteorological, Climatological and Geophysical Agency, Jakarta (Indonesia)

    2015-04-24

    East Java has a fairly complex geological structure. Physiographically East Java can be divided into three zones, i.e. the Southern Mountains zone in the southern part, the Kendeng zone in the middle part, and the Rembang zone in the northern part. Most of the seismic hazards in this region are due to processes in the upper crust. In this study, the Ambient Noise Tomography (ANT) method is used to image the upper crustal structure beneath East Java. We have used seismic waveform data recorded by 8Meteorological, Climatological and Geophysical Agency (BMKG) stationary seismographic stations and 16 portable seismographs installed for 2 to 8 weeks. The data were processed to obtain waveforms fromnoise cross-correlation between pairs of seismographic stations. Our preliminary results indicate that the Kendeng zone, an area of low gravity anomaly, is associated with a low velocity zone. On the other hand, the southern mountain range, which has a high gravity anomaly, is related to a high velocity anomaly as shown by our tomographic images.

  6. The DEEP-South: Preliminary Photometric Results from the KMTNet-CTIO

    Science.gov (United States)

    Kim, Myung-Jin; Moon, Hong-Kyu; Choi, Young-Jun; Yim, Hong-Suh; Bae, Youngho; Roh, Dong-Goo; the DEEP-South Team

    2015-08-01

    The DEep Ecliptic Patrol of the Southern sky (DEEP-South) will not only conduct characterization of targeted asteroids and blind survey at the sweet spots, but also utilize data mining of small Solar System bodies in the whole KMTNet archive. As round-the-clock observation with the KMTNet is optimized for spin characterization of tumbling and slow-rotating bodies as it facilitates debiasing previously reported lightcurve observations. It is also most suitable for detection and rapid follow-up of Atens and Atiras, the “difficult objects” that are being discovered at lower solar elongations.For the sake of efficiency, we implemented an observation scheduler, SMART (Scheduler for Measuring Asteroids RoTation), designed to conduct follow-up observations in a timely manner. It automatically updates catalogs, generates ephemerides, checks priorities, prepares target lists, and sends a suite of scripts to site operators. We also developed photometric analysis software called ASAP (Asteroid Spin Analysis Package) that aids to find a set of appropriate comparison stars in an image, to derive spin parameters and reconstruct lightcurve simultaneously in a semi-automatic manner. In this presentation, we will show our preliminary results of time series analyses of a number of km-sized Potentially Hazardous Asteroids (PHAs), 5189 (1990 UQ), 12923 (1999 GK4), 53426 (1999 SL5), 136614 (1993 VA6), 385186 (1994 AW1), and 2000 OH from test runs in February and March 2015 at the KMTNet-CTIO.

  7. Numerical and experimental study of local heat transfer enhancement in helically coiled pipes. Preliminary results.

    Science.gov (United States)

    Bozzoli, F.; Cattani, L.; Rainieri, S.; Zachár, A.

    2015-11-01

    In the last years, the attention of heat transfer equipments manufacturers turned toward helically coiled-tube heat exchangers, especially with regards to applications for viscous and/or particulate products. The recent progress achieved in numerical simulation motivated many research groups to develop numerical models for this kind of apparatuses. These models, intended both to improve the knowledge of the fundamental heat transfer mechanisms in curved geometries and to support the industrial design of this kind of apparatuses, are usually validated throughout the comparison with either theoretical or experimental evidences by considering average heat transfer performances. However, this approach doesn't guarantee that the validated models are able to reproduce local effects in details, which are so important in this kind of non-standard geometries. In the present paper a numerical model of convective heat transfer in coiled tubes for laminar flow regime was formulated and discussed. Its goodness was checked throughout the comparison with the latest experimental outcomes of Bozzoli et al. [1] in terms of convective heat flux distribution along the boundary of the duct, by ensuring the effectiveness of the model also in the description of local behaviours. Although the present paper reports only preliminary results of this simulation/validation process, it could be of interest for the research community because it proposes a novel approach that could be useful to validate many numerical models for nonstandard geometries.

  8. Characterization of sediments from Voglajna and Savinja rivers – preliminary results

    Directory of Open Access Journals (Sweden)

    Stanislav Frančišković-Bilinski

    2002-12-01

    Full Text Available Preliminary mineralogical, geochemical and Mössbauer studies of six surface sediments (fraction <63 μm from Voglajna and Savinja rivers (Slovenia are reported for the first time. The location was chosen because of two reasons. One was possible pollution due to industry in Celje. Another was presumed high concentration of iron (later found 2.8 – 5.6 %, easily studied by Mössbauer spectroscopy. XRD data showed that quartz is present in all samples. Other minerals are different in different locations. Iron can be present in Fe-chlorite and in montmorillonite, found by XRD as trace minerals. Microelements were determined by ICP-MS method. Sediment of Voglajna near Štore contain the highest concentrations of S, P, Cr, Ni, Pb, Cu, Mo, Sb, W and Hg. Sediment of Savinja at Tremerje contain the highest concentrations of Zn, Cd, Ag and Au. These results indicate industrial pollution around Celje. Further characterization of Fe (II and Fe (III was performed by 57Fe Mössbauer spectroscopy at room temperature. Spectra were fitted with two and in one case with three doublets. In addition to the presence of two doublets, two magnetic sextets are present in the sediment of Voglajna at Štore, suggesting minor quantity of Fe3O4. The Fe (III / Fe (II ratio decreases downstream the Voglajna river. The work is in progress on additional sampling stations.

  9. PRELIMINARY RESULTS OF QUALITY STUDY OF WATER FROM SMALL MICHALICE RESERVOIR ON WIDAWA RIVER

    Directory of Open Access Journals (Sweden)

    Mirosław Wiatkowski

    2014-10-01

    Full Text Available The paper presents an analysis of water quality of the small Michalice reservoir. A preliminary assessment of the reservoir water quality and its usability was made. The quality of water in the reservoir is particularly important as the main functions of the reservoir are agricultural irrigation, recreation and flood protection . The following physico-chemical parameters of the Widawa River were analyzed: NO3 -, NO2 -, NH4 +, PO4 3-, COD, water temperature, pH and electrolytic conductivity. Main descriptive statistical data were presented for the analyzed water quality indicators. The research results indicate that the reservoir contributed to the reduced concentrations of the following water quality indicators: nitrates, nitrites, phosphates, electrolytic conductivity and COD (in the outflowing water – St.3 in comparison to the water flowing into the reservoir – St.1. In the water flowing out of the Psurów reservoir higher values of the remaining indicators were observed if compared with the inflowing water. It was stated, as well, that analised waters are not vulnerable to nitrogen compounds pollution coming from the agricultural sources and are eutrophic. For purpose obtaining of the précised information about condition of Michalice reservoir water purity as well as river Widawa it becomes to continue the hydrological monitoring and water quality studies.

  10. Two-dimensional computer simulation of hypervelocity impact cratering: some preliminary results for Meteor Crater, Arizona

    International Nuclear Information System (INIS)

    A computational approach used for subsurface explosion cratering was extended to hypervelocity impact cratering. Meteor (Barringer) Crater, Arizona, was selected for the first computer simulation because it is one of the most thoroughly studied craters. It is also an excellent example of a simple, bowl-shaped crater and is one of the youngest terrestrial impact craters. Initial conditions for this calculation included a meteorite impact velocity of 15 km/s, meteorite mass of 1.67 x 108 kg, with a corresponding kinetic energy of 1.88 x 1016 J (4.5 megatons). A two-dimensional Eulerian finite difference code called SOIL was used for this simulation of a cylindrical iron projectile impacting at normal incidence into a limestone target. For this initial calculation, a Tillotson equation-of-state description for iron and limestone was used with no shear strength. Results obtained for this preliminary calculation of the formation of Meteor Crater are in good agreement with field measurements. A color movie based on this calculation was produced using computer-generated graphics. 19 figures, 5 tables, 63 references

  11. Preliminary result of earthquake hypocenter determination using hypoellipse around western Java region

    Science.gov (United States)

    Supendi, Pepen; Nugraha, Andri Dian

    2016-05-01

    West Java region is located in high seismicity and active tectonic setting region influenced by subducting Indo-Australian plate beneath Eurasia plate. There are several on land active faults namely Cimandiri fault, Lembang fault, and Baribis fault in the region. MCGA earthquake data catalog from 2009 to 2014 shows the earthquakes were located not only around active faults but also relatively far away from the active faults in West Java region. In this study, we determined the earthquake location through re-picking of P-and S-wave arrival times recording by MCGA network. Earthquake location was determined by using Hypoellipse code that employs a single event determination method. We then relocated the events using hypocenter double-difference method. We also have been conducting focal mechanism analysis to estimate the type of fault slip. Our preliminary results show generally the epicenter location were distributed around the on land active fault which have the focus depth less than 30 km. For ongoing and future works, we have been determining focal mechanism of selected event related to on land active fault for this region..

  12. Gamma radiation measurement in select sand samples from Camburi beach - Vitoria, Espirito Santo, Brazil: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Barros, Livia F.; Pecequilo, Brigitte R.S.; Aquino, Reginaldo R., E-mail: lfbarros@ipen.b, E-mail: brigitte@ipen.b, E-mail: raquino@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    The variation of natural radioactivity along the surface of the beach sands of Camburi, located in Vitoria, capital of Espirito Santo, southeastern Brazil, was determined from the contents of {sup 226}Ra, {sup 232}Th and {sup 40}K. Eleven collecting points was selected along all the 6 km extension of the Camburi beach. Sand samples collected from all established points on January 2011 were dried and sealed in standard 100 mL polyethylene flasks and measured by high resolution gamma spectrometry after a 4 weeks ingrowth period, in order to allow the secular equilibrium in the {sup 238}U and {sup 232}Th series. The {sup 226}Ra concentration was determined from the weighted average concentrations of {sup 214}Pb and {sup 214}Bi. The {sup 232}Th concentration was determined from the weighted average concentrations of {sup 228}Ac, {sup 212}Pb and {sup 212}Bi and the {sup 40}K from its single gamma transition. Preliminary results show activity concentrations varying from 5 Bq.kg{sup -1} to {sup 222} Bq.kg{sup -1} for {sup 226}Ra and from 14 Bq.kg{sup -1} to 1074 Bq.kg{sup -'}1 for {sup 232}Th, both with the highest values for Camburi South and Central. For {sup 40}K, the activity concentrations ranged from 14 Bq.kg{sup -1} to 179 Bq.kg{sup -1} and the highest values were obtained for Camburi South. (author)

  13. Extremity exposure in nuclear medicine: preliminary results of a European study.

    Science.gov (United States)

    Sans Merce, M; Ruiz, N; Barth, I; Carnicer, A; Donadille, L; Ferrari, P; Fulop, M; Ginjaume, M; Gualdrini, G; Krim, S; Mariotti, F; Ortega, X; Rimpler, A; Vanhavere, F; Baechler, S

    2011-03-01

    The Work Package 4 of the ORAMED project, a collaborative project (2008-11) supported by the European Commission within its seventh Framework Programme, is concerned with the optimisation of the extremity dosimetry of medical staff in nuclear medicine. To evaluate the extremity doses and dose distributions across the hands of medical staff working in nuclear medicine departments, an extensive measurement programme has been started in 32 nuclear medicine departments in Europe. This was done using a standard protocol recording all relevant information for radiation exposure, i.e. radiation protection devices and tools. This study shows the preliminary results obtained for this measurement campaign. For diagnostic purposes, the two most-used radionuclides were considered: (99m)Tc and (18)F. For therapeutic treatments, Zevalin(®) and DOTATOC (both labelled with (90)Y) were chosen. Large variations of doses were observed across the hands depending on different parameters. Furthermore, this study highlights the importance of the positioning of the extremity dosemeter for a correct estimate of the maximum skin doses.

  14. Preliminary Results from Hydrologic Monitoring of Mill and Farm Ponds in Burgundy, France

    Science.gov (United States)

    Strano, S.; Misner, T.; Rosenmeier, M.; Bain, D.; Straffin, E.

    2008-12-01

    This paper presents the preliminary results from a year-long intensive hydrologic monitoring study completed in three small freshwater reservoirs (mill and farm ponds) within the Arroux River Valley, Burgundy, France. The study includes assessment of the seasonal variability of reservoir water levels and chemistry and hydrologic modeling of the watersheds. Several shallow monitoring wells were installed around each reservoir, and groundwater and surface water inflows and outflows were sampled monthly. All water samples were analyzed for major cations (Na, Mg, K, Ca) and anions (F, Cl, SO4, NO2, NO3) as well as stable isotopic composition. Monthly well and continuous reservoir water levels were also recorded. The water monitoring data was combined with nearby weather station data (available from 1955 to present) to model the hydroclimatology and hydrogeochemistry of the reservoirs. This modern data will be used to interpret (i.e., calibrate and validate) geochemical records from sediment cores collected from the reservoirs, which date to at least 1200 A.D. Modern watershed and sediment core data will also be compared with known local land use histories to examine the relative influence of climate and human activity on watershed dynamics. This work thus has broad implications for many watershed studies where historical records of land use and climate change are not available but instead are inferred from geological or ecological evidence.

  15. Preliminary results of equation of state measurements using imaging x-ray Thomson spectrometer

    Science.gov (United States)

    Belancourt, Patrick; Theobald, Wolfgang; Keiter, Paul; Collins, Timothy; Bonino, Mark; Kozlowski, Pawel; Drake, Paul; University of Michigan Team; LaboratoryLaser Energetics Team; University of Oxford Team

    2014-10-01

    Understanding the equation of state of materials under shocked conditions is important for laboratory astrophysics and high-energy-density physics experiments. The goal of the experiments discussed here is to create a platform for equation of state measurements in shocked foams on Omega EP. The target of interest for these experiments is shocked carbonized resorcinol formaldehyde foam with an initial density of 0.34 g/cc. Lasers irradiate an ablator, driving a shock into the foam. Plasma conditions ahead of the shock, at the shock and behind the shock are diagnosed using the imaging x-ray Thomson spectrometer (IXTS). The IXTS is capable of spectrally resolving the scattered x-ray beam while imaging in one spatial dimension. Preliminary results from these experiments will be shown. This work is funded by the U.S. Department of Energy, through the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, grant number DE-NA0001840, and the National Laser User Facility Program, Grant Number DE-NA0000850, and through the Laboratory for Laser Energetics, University of Rochester by the NNSA/OICF under Cooperative Agreement No. DE-FC52-08NA28302.

  16. Preliminary results of CCD observations of Himalia at Yunnan Observatories in 2015

    CERN Document Server

    Peng, H W; Peng, Q Y

    2016-01-01

    In order to study the potential in high precision CCD astrometry of irregular satellites, we have made experimental observations for Himalia, the sixth and irregular satellite of Jupiter. A total of 185 CCD observations were obtained by using the 2.4 m telescope and 1 m telescope at Yunnan Observatories over ten nights. Preliminary analysis for the observations were made, including the geometric distortion, the atmospheric refraction, and also the phase effect. All positions of Himalia are measured relative to the reference stars from the catalogue UCAC4 in each CCD field of view. The theoretical positions of Himalia were retrieved from the IMCCE, while the positions of Jupiter were obtained based on the planetary theory INPOP13C. The results show that the mean (O-C) (observed minus computed) residuals are -0.004 and -0.002 arcsec in right ascension and declination, respectively. The standard deviation of (O-C) residuals are estimated at about 0.04 arcsec in each direction.

  17. Preliminary results of the LLNL airborne experimental test-bed SAR system

    Energy Technology Data Exchange (ETDEWEB)

    Miller, M.G.; Mullenhoff, C.J.; Kiefer, R.D.; Brase, J.M.; Wieting, M.G.; Berry, G.L.; Jones, H.E.

    1996-01-16

    The Imaging and Detection Program (IDP) within Laser Programs at Lawrence Livermore National Laboratory (LLNL) in cooperation with the Hughes Aircraft Company has developed a versatile, high performance, airborne experimental test-bed (AETB) capability. The test-bed has been developed for a wide range of research and development experimental applications including radar and radiometry plus, with additional aircraft modifications, optical systems. The airborne test-bed capability has been developed within a Douglas EA-3B Skywarrior jet aircraft provided and flown by Hughes Aircraft Company. The current test-bed payload consists of an X-band radar system, a high-speed data acquisition, and a real-time processing capability. The medium power radar system is configured to operate in a high resolution, synthetic aperture radar (SAR) mode and is highly configurable in terms of waveforrns, PRF, bandwidth, etc. Antennas are mounted on a 2-axis gimbal in the belly radome of the aircraft which provides pointing and stabilization. Aircraft position and antenna attitude are derived from a dedicated navigational system and provided to the real-time SAR image processor for instant image reconstruction and analysis. This paper presents a further description of the test-bed and payload subsystems plus preliminary results of SAR imagery.

  18. Development of transmissometer system for evaluating molecular contamination effects and the preliminary results

    Science.gov (United States)

    Itoh, Nobunari; Katoh, Masahiro; Okano, Nobuaki

    2005-01-01

    The presence of propagated molecular gas is one of the most probable causes of on-orbit degradation. The performance of optical sensors would be affected seriously if the strong absorption bands of the contaminants exist in the region of our interest and phase transition of adsorption gas on optical surfaces would induce not only absorption but also scatter. Although there are amount of trials to predict spectral degradation with model calculations, experimental approaches are also necessary to clarify degradation processes occurred in orbit and to improve the on-board calibration reliability. We built up the measurement system in order to evaluate transmittance degradation with various kinds of gases under different temperature and vacuum conditions. In our system, an optical glass, the site of adsorption, is set inside a cryostat and then a certain amount of molecular gas is injected. The amount of injected gas adsorption onto the optical surface is controlled by adjusting the sample surface temperature. Our systems have the capability to control vacuum within the range from 10-3Pa to 102Pa and temperature from 150K to 423K. As for the measurement of transmittance change, we adopted commercially available spectrophotometer and FTIR. The optical spectrophotometer covers the wavelength range from 300nm to 2.5um and the FTIR covers from 2um to 25um. We would present the details of our system and discuss about measurement accuracy and preliminary results of our measurements.

  19. REGAT: The Algerian Permanent GPS Network. Strategy, configuration and preliminary results.

    Science.gov (United States)

    Yelles-Chaouche, Abdelkarim; Lammali, Kamel; Bellik, Amar; Mahsas, Abdelhakim; Bacha, Wahab; Bougrine, Amina

    2013-04-01

    Northern Algeria, located along the Eurasiatic-African boundary plate is characterised by a moderate to strong seismic activity. During History, some violent earthquakes occurred mainly in the Atlas region, particularly in the Tellian area, leading sometimes to destruction of major cities of Algeria (Algiers, 1716; Oran, 1790; Blida, 1825; El Asnam, 1980; Constantine, 1985; Boumerdes, 2003…). In order to improve the knowledge of the deformation pattern of the Atlasic region, and more globally of the African (Nubia)-Eurasia plate boundary along the Algerian margin, the Research Center of Astronomy, Astrophysics and Geophysics (CRAAG) started since six year to implement a permanent GPS network. The REGAT (REseau Géodésique de l'Atlas), consists on a set of 56 continuous GPS stations deployed in the Atlas region, from the coastal area to the Sahara Platform with one station at Tamanrasset, in the southern part of the country. The deployment strategy consisted in two phases: - The first one began on 2004 with 14 stations installed - The second phase, which started in 2011concerns a set of 42 stations. We present here the procedure used to collect, store and process the GPS data from the REGAT network and present the preliminary results of the stations which observed more than three years. Keywords: Earthquake, GPS, Networks, REGAT.

  20. The Geographic Climate Information System Project (GEOCLIMA): Overview and preliminary results

    Science.gov (United States)

    Feidas, H.; Zanis, P.; Melas, D.; Vaitis, M.; Anadranistakis, E.; Symeonidis, P.; Pantelopoulos, S.

    2012-04-01

    The project GEOCLIMA aims at developing an integrated Geographic Information System (GIS) allowing the user to manage, analyze and visualize the information which is directly or indirectly related to climate and its future projections in Greece. The main components of the project are: a) collection and homogenization of climate and environmental related information, b) estimation of future climate change based on existing regional climate model (RCM) simulations as well as a supplementary high resolution (10 km x 10 km) simulation over the period 1961-2100 using RegCM3, c) compilation of an integrated uniform geographic database, and d) mapping of climate data, creation of digital thematic maps, and development of the integrated web GIS application. This paper provides an overview of the ongoing research efforts and preliminary results of the project. First, the trends in the annual and seasonal time series of precipitation and air temperature observations for all available stations in Greece are assessed. Then the set-up of the high resolution RCM simulation (10 km x 10 km) is discussed with respect to the selected convective scheme. Finally, the relationship of climatic variables with geophysical features over Greece such as altitude, location, distance from the sea, slope, aspect, distance from climatic barriers, land cover etc) is investigated, to support climate mapping. The research has been co-financed by the European Union (European Regional Development Fund) and Greek national funds through the Operational Program "Competitiveness and Entrepreneurship" of the National Strategic Reference Framework (NSRF) - Research Funding Program COOPERATION 2009.

  1. Aerobic Capacity Following Long Duration International Spaces Station (ISS) Missions: Preliminary Results

    Science.gov (United States)

    Moore, Alan D.; Lee, S.M.C.; Everett, M.E.; Guined, J.R.; Knudsen, P.

    2010-01-01

    Maximum oxygen uptake (VO2max) is reduced immediately following space flights lasting 6%. WRmax also decreased on R+1/2 compared to preflight (Pre: 245+/-69, R+1/2: 210+/-45 W). On R+10, VO2max was 2.86+/-0.62 L(dot)/min, with 2 subjects still demonstrating a loss of > 6% from preflight. WRmax on R+10 was 240+/-49 W. HRmax did not change from pre to post-flight. Conclusions: These preliminary results, from the first 5 of 12 planned subjects of an ongoing ISS study, suggest that the majority of astronauts will experience a decrease in VO2max after long-duration space-flight. Interestingly, the two astronauts with the highest preflight VO2max had the greatest loss on R+1/2, and the astronaut with the lowest preflight VO2max increased by 13%. Thus, maintenance of VO2max may be more difficult in astronauts who have a high aerobic capacity, perhaps requiring more intense in-flight exercise countermeasure prescriptions.

  2. Elemental composition of size-fractionated urban aerosol collected in Florence, Italy; preliminary results

    Science.gov (United States)

    Del Carmine, P.; Lucarelli, F.; Mandò, P. A.; Valerio, M.; Prati, P.; Zucchiatti, A.

    1999-04-01

    An extensive investigation is in progress aiming at the characterisation of the air particulate composition in Florence. We present here the preliminary results concerning the analysis of size-fractionated aerosol samples taken by two-stage streaker samplers in two sites characterised by different urban settings (one in a heavy traffic area, one in a green area). The sampling period (21 January-22 February) includes two days during which the Municipality of Florence has banned the circulation of non-catalytic cars, due to the increase of NO 2 above the "recommended safety values". Hourly concentrations of 20 elements from Na to Pb were determined using the external beam PIXE facility of the I.N.F.N. Van de Graaff accelerator at the Physics Department of the Florence University. Factor analysis on the data set confirms that traffic is the main source of atmospheric pollution in Florence. The ban of non-catalytic cars seems to have produced no effect on the concentration of detected elements (in particular Pb and Br).

  3. Epigenetic perturbations in the pathogenesis of mustard toxicity; hypothesis and preliminary results

    International Nuclear Information System (INIS)

    The pathogenesis of sulfur mustard (SM) toxicity is not fully understood, although it is related to reactive oxygen and nitrogen species, oxidative stress, DNA damage, poly (ADP-ribose) polymerase activation within the affected cell. We, therefore, made an attempt whether epigenetic aberrations may contribute to pathogenesis of SM poisoning in rats' lung. A total of 40 male SD rats were divided into 4 groups. Group 1 served as control and given 2 ml saline, three groups received single dose of mechlorethamine (MEC) (3.5 mg/kg subcutaneously) with the same time intervals. Group 2 received MEC only; group 3 received histone deacetylase (HDAC) inhibitor (Trichostatine A) (1 mg/kg) and group 4 received DNA methyl transferase (DNMT) inhibitor (5-Azacytidine) (0.02 mg/kg), intraperitoneally. MEC injection resulted in severe lung toxicity with strong interstitial and alveolar edema, hemorrhage, emphysematous changes as well as mild inflammatory cell infiltration and septal thickening. In group 3, the HDAC inhibitor significantly reduced interstitial and alveolar edema, hemorrhage and inflammatory cell infiltration. On the other hand, we have observed severe lung damage by using DNMT inhibitor (group 4). In HDAC inhibitor group, the results were close to sham group. In DNMT inhibitor group, however, lungs were worse than MEC group results. These preliminary results revealed that, SM itself and/or its intracellular metabolites may perturb the epigenetic environment of the affected cell in lung tissue. Hypothetically, MEC may cause HDAC induction leading to a variety of gene silencing. Trichostatine A can reduce the active enzyme level and can reactivate the already silenced genes. Further studies are needed to clarify the involvement of epigenetic perturbations in the pathogenesis of mustard toxicity.(author)

  4. Periglacial shallow lakes offer information about climate change. Preliminary results, King George Island

    International Nuclear Information System (INIS)

    South Shetland Islands (northern Antarctic Peninsula) represent one of the worlds areas most affected by the retreat of glaciers due to global warming. As pointed by Ingolfsson, during the last 100 years the climatic development in the western Antarctic Peninsula region has moved from a relatively cold regime to an increasingly warm regime. A large number of evidences indicate that melt water and sediment transport have increased during the past 50 years.The King George Island (KGI) ice cap, its high sensitivity to climate changes, thermal regime, ablation rates, distribution, etc. and its relation with the relative sea level, have been deeply studied and this behavior is generally extensive to the South Shetland Islands ice caps. However, there are not many recent dating studies in this area. Radiometric dating is the main way to quantify (retrospectively) the rates of various geo-hydro environmental processes of interest and further work is necessary to constrain timescales of these processes affected by recent climate changes. The few available dating studies of lacustrine sediments are restricted to lakes of sufficient size and depth, which are not widespread and have a very uneven spatial distribution. On the other hand, there are many small shallow peri glacial lagoons having a better spatial distribution, especially with respect to the fronts of receding glaciers. These lagoons are typically discarded for recent dating studies, due to a number of technical reasons. In this paper, for the first time, we present the preliminary results of a recent radiometric dating (210Pb and 137Cs) from a peri glacial shallow lagoon on Fildes Peninsula (KGI) and discuss the results in the context of the local geology and climatic conditions during the last century.The lagoon is located near the Collins Glacier retreat border and the results indicates that besides the upper sediment layers may be frozen during winter time, the stratigraphic information is still preserved and

  5. Practical applicability and preliminary results of the Baltic Environmental Satellite Remote Sensing System (SatBaltic)

    Science.gov (United States)

    Wozniak, B.; Ostrowska, M.; Bradtke, K.; Darecki, M.; Dera, J.; Dudzinska-Nowak, J.; Dzierzbicka, L.; Ficek, D.; Furmanczyk, K.; Kowalewski, M.; Krezel, A.; Majchrowski, R.; Paszkuta, M.; Ston-Egiert, J.; Stramska, M.; Zapadka, T.

    2012-04-01

    SatBaltic (Satellite Monitoring of the Baltic Sea Environment) project is being realized in Poland by the SatBaltic Scientific Consortium, specifically appointed for this purpose, which associates four scientific institutions: the Institute of Oceanology PAN in Sopot - coordinator, the University of Gdańsk (Institute of Oceanography), the Pomeranian Academy in Słupsk (Institute of Physics) and the University of Szczecin (Institute of Marine Sciences). We present the first the results of the first year and a half of SatBaltic's implementation. The final result of the project is to be the creation and setting in motion of the SatBaltic Operational System (SBOS), the aim of which is to monitor effectively and comprehensively the state of the Baltic Sea environment using remote sensing techniques. Various aspects of the practical applicability of SBOS to the monitoring of the Baltic ecosystem are discussed. We present some examples of the maps of the various characteristics of the Baltic obtained using the current version of SBOS, including algorithms and models that are still in an unfinished state. At the current stage of research, these algorithms apply mainly to the characteristics of the solar energy influx and the distribution of this energy among the various processes taking place in the atmosphere-sea system, and also to the radiation balance of the sea surface, the irradiance conditions for photosynthesis and the condition of plant communities in the water, sea surface temperature distributions and some other marine phenomena correlated with this temperature. Also given are results of preliminary inspections of the accuracy of the magnitudes shown on the maps.

  6. Radioimmunodetection of non-Hodgkin`s lymphoma with radiolabelled LL2 monoclonal antibody. Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Gasparini, M.; Buraggi, G.L.; Tondini, C. [Istituto Nazionale dei Tumori, Milano (Italy)] [and others

    1994-05-01

    Radioimmunodetection (RAID) with 99m technetium labelled B cell lymphoma monoclonal antibody (MAb) (IMMU-LL2 Fab`, Immunomedics, Inc., Morris Plains, N.J.) was investigated in 8 patients (5 female and 3 male; age range 20-72 years) with histologically proven non-Hodgkin`s lymphoma (NHL). Of the 8 lymphomas, 5 were intermediate grade and 3 low grade. Whole body images with multiple planar views were obtained at 30 min, 4-6 and 24 hours after the I.V. injection of 1 mg LL2-Fab` labelled with 20-25 mCi (740-925 MBq) {sup 99}Tc. SPECT of chest or abdomen was performed at 5-8 hours after injection in all patients. No adverse reactions were observed in any patient after MAb infusion and no appreciable changes were seen in the blood counts, renal and liver function tests. A total of 17 of 18 (94.4%) lymphoma lesions were detected by RAID. All the tumor localizations were confirmed by clinical examination and with other imaging techniques, such as CT scan, MRI or gallium scan. In this series of patients no false positive results were noted and only 1 false negative resulted in a patient who had a mediastinal bulky disease. As regard the biodistribution of the immunoreagent we can make the following conclusions: (1) no appreciable bone marrow activity was seen, (2) splenic targeting was demonstrated in all patients, (3) tumor-to-non tumor ratios ranged from 1.2 to 2.8 as measured by ROI technique, (4) no difference of uptake was noted for different tumor grades. The images performed 24 hours after injection did not detect new lesions, but areas of doubtful uptake were seen as positive focal areas in the delayed scan. In these preliminary results the LL2-Fab` MAb seems to be useful for detection, staging and follow up of NHL patients.

  7. 78 FR 67112 - Fresh Garlic From the People's Republic of China: Preliminary Results of New Shipper Review of...

    Science.gov (United States)

    2013-11-08

    ... Results of Antidumping Duty Administrative Review and Final Rescission, in Part, 72 FR 58809 (October 17... International Trade Administration Fresh Garlic From the People's Republic of China: Preliminary Results of New... Co., Ltd. (Goodman) under the antidumping duty order on fresh garlic from the People's Republic...

  8. 77 FR 25136 - Seamless Refined Copper Pipe and Tube From Mexico: Preliminary Results of Antidumping Duty New...

    Science.gov (United States)

    2012-04-27

    ... exported by Golden Dragon \\1\\ were not sold below normal value (NV). If these preliminary results are... Results of New Shipper Review'' section of this notice. \\1\\ The Department uses the name Golden Dragon when we refer to the collective group of Golden Dragon companies, which includes GD Affiliates....

  9. Robotic Esophagectomy for Cancer: Early Results and Lessons Learned.

    Science.gov (United States)

    Cerfolio, Robert J; Wei, Benjamin; Hawn, Mary T; Minnich, Douglas J

    2016-01-01

    Minimally invasive esophagectomy with intrathoracic dissection and anastomosis is increasingly performed. Our objectives are to report our operative technique, early results and lessons learned. This is a retrospective review of 85 consecutive patients who were scheduled for minimally invasive Ivor Lewis esophagectomy (laparoscopic or robotic abdominal and robotic chest) for esophageal cancer. Between 4/2011 and 3/2015, 85 (74 men, median age: 63) patients underwent robotic Ivor Lewis esophageal resection. In all, 64 patients (75%) had preoperative chemoradiotherapy, 99% had esophageal cancer, and 99% had an R0 resection. There were no abdominal or thoracic conversions for bleeding. There was 1 abdominal conversion for the inability to completely staple the gastric conduit. The mean operative time was 6 hours, median blood loss was 35ml (no intraoperative transfusions), median number of resected lymph nodes was 22, and median length of stay was 8 days. Conduit complications (anastomotic leak or conduit ischemia) occurred in 6 patients. The 30 and 90-day mortality were 3/85 (3.5%) and 9/85 (10.6%), respectively. Initial poor results led to protocol changes via root cause analysis: longer rehabilitation before surgery, liver biopsy in patients with history of suspected cirrhosis, and refinements to conduit preparation and anastomotic technique. Robotic Ivor Lewis esophagectomy for cancer provides an R0 resection with excellent lymph node resection. Our preferred port placement and operative techniques are described. Disappointingly high thoracic conduit problems and 30 and 90-day mortality led to lessons learned and implementation of change which are shared. PMID:27568155

  10. Preliminary report. Concomitant irradiation and paclitaxel as radiosensitizer to increase the operability of unresectable locally advanced breast cancer

    International Nuclear Information System (INIS)

    The objective of this non-randomized, single-arm pilot study was to investigate whether paclitaxel (50 mg/m2 body surface area) concomitantly administered with radiation (2 Gy/fr, total 50 Gy) could increase the operability of unresectable locally advanced breast cancer (LABC). Operability was assessed based on the Haagensen criteria, toxicity based on EORTC criteria, and response to therapy based on WHO criteria. Thus far 13 inoperable LABC patients have participated in the study as subjects in the treatment group, and 12 of the cases have been analyzable. As a result of radiopaclitaxel therapy, 10 of the 12 tumors became operable (>83%), and in 3 of the 10 patients there was no evidence of residual tumor. To date there have been no cases of local relapse in the treatment group. Given these results, the preliminary conclusions of the study are as follows: The results of radiochemotherapy, specifically with radiopaclitaxel, are quite promising as a method of treating inoperable LABC by reducing tumor size until it becomes operable. The efficacy and safety of the 50 mg/m2 body surface area dose of paclitaxel were adequate, allowing use of higher doses with the expectation of better results. The schedule of administration in this study yielded effective results. (K.H.)

  11. Preliminary results of high resolution magneto-biostratigraphy of continental sequences in Chapala Basin, Southwestern Mexico

    Science.gov (United States)

    Mendez Cardenas, D. L.; Benammi, M.

    2007-05-01

    Chapala Lake is south from Guadalajara, Jalisco State (Southwestern Mexico). Belongs to a series of Pliocenic lakes along the Mexican Volcanic Belt. It is localized in the Chapala rift, and the entire area is controlled by the tectonic setting of the Colima, Tepic and Chapala rifts, constituting the triple junction rift-rift-rift. The deposits studied belong to volcanosedimentary sequences, composed by lacustrine and fluvial associations alternated with units of ash and pumice. The faunistic component reported consists at least of 27 mammals species, and the sediments were there're in have to work with special attention for seek rodents by handpicking. Probably these rodents will be the clue to determine the deposits correlation. Core demagnetization shows that they are low-coercivity magnetic minerals like magnetite or Ti-magnetite. It was verified that the characteristic magnetization corresponds to MNRp and the inversion test resulted good. Rodents are represented by Geomynae, Sigmondontinae and Sciurinae. The Geomynae family is the most common, and the faunistic association indicates Blancan age. This also allows a correlation with the polarity pattern in the GSS between 3,6 and 2,6 Ma. Actually, is known that this kind of studies in continental sequences supported with paleontological record of vertebrates could give us a more precised calibration of the age of such deposits. Allowing better understanding of the evolution of these mammals and their path trough geological record. This work shows the preliminary results of rodents palaeontology and high resolution magneto-stratigraphy in the units from to Chapala Basin.

  12. Functional MRI evidence for language plasticity in adult epileptic patients: Preliminary results

    Directory of Open Access Journals (Sweden)

    Emilie Cousin

    2008-03-01

    Full Text Available Emilie Cousin1, Monica Baciu1, Cédric Pichat1, Philippe Kahane2, Jean-François Le Bas31UMR CNRS/UPMF 5105, Laboratoire de Psychologie et Neurocognition; 2Laboratoire de Neurophysiopathologie de l’Epilepsie, CHU Grenoble; 3Unité IRM, CHU Grenoble, FranceAbstract: The present fMRI study explores the cerebral reorganisation of language in patients with temporal lobe epilepsy, according to the age of seizures onset (early or late and the hippocampal sclerosis (associated or not. Seven right-handed control volunteers and seven preoperative adult epileptic patients performed a rhyme decision (language condition and a visual detection (control condition tasks in visually presented words and unreadable characters, respectively. All patients were left hemisphere dominant for language. Appropriate statistical analyses provided the following preliminary results: (1 patients compared with healthy subjects showed lower degree of hemispheric lateralization with supplementary involvement of the right hemisphere; (2 the degree of hemispheric specialization depends on the considered region; (3 patients with early seizures show signs of temporal and parietal reorganization more frequently than patients with late onset of seizures; (4 patients with early seizures show a tendency for intra-hemispheric frontal reorganisation; (5 associated hippocampal sclerosis facilitates the inter-hemispheric shift of temporal activation. Although our patients were left hemisphere predominant for language, the statistical analyses indicated that the degree of lateralization was significantly lower than in healthy subjects. This result has been considered as the indication of atypical lateralization of language.Keywords: language, fMRI, plasticity, temporal epilepsy, age, hippocampal sclerosis

  13. Preliminary results from a detritiation facility dedicated to soft housekeeping waste

    International Nuclear Information System (INIS)

    Highlights: ► The results of the first detritiation campaign of soft housekeeping are presented. ► 120 to 150 °C increasing temperature reveals a strong rise of the detritiation yield. ► Using Ar–2%O2 declassifies the sample from ILW to LLW (UK) in 18 h. ► Carrier gas – H2 explosive risk is assessed before membrane reactor implementation. ► The optimized conditions are Ar–2%O2 at 150 °C. - Abstract: Nuclear waste management has to be taken into account for fusion machine in tritium experimentations. Soft housekeeping waste is produced during both operating and dismantling phases and is contaminated by tritium under reduced (HT) and oxidized (HTO) forms. At CEA Cadarache, a lab-scaled facility has been built for soft housekeeping detritiation. The tritiated gas exhausted from the process described above is foreseen to be treated by a tubular Pd–Ag membrane reactor, for gaseous tritium recovery. Since this membrane reactor uses hydrogen as swamping gas the compatibility toward explosive hazard has to be taken into account. Then, this work presents a double objective. A first study is presented in order to identify the best conditions for the declassification of soft housekeeping waste, without tritium recovery. Experiments carried out at 120 °C are not efficient enough and do not allow one to choose the most efficient carrier gas. Some other tests are being currently performed at higher temperatures (150 °C). Moreover, due to safety issues, the use of air has to be avoided during membrane reactor implementation phase. Preliminary results obtained with hydrogen hazard-free carrier gases are also presented.

  14. Corneal tissue water content mapping with THz imaging: preliminary clinical results (Conference Presentation)

    Science.gov (United States)

    Sung, Shijun; Bajwa, Neha; Deng, Sophie X.; Taylor, Zachary; Grundfest, Warren

    2016-03-01

    Well-regulated corneal water content is critical for ocular health and function and can be adversely affected by a number of diseases and injuries. Current clinical practice limits detection of unhealthy corneal water content levels to central corneal thickness measurements performed by ultrasound or optical coherence tomography. Trends revealing increasing or decreasing corneal thickness are fair indicators of corneal water content by individual measurements are highly inaccurate due to the poorly understood relationship between corneal thickness and natural physiologic variation. Recently the utility of THz imaging to accuarately measure corneal water content has been explored on with rabbit models. Preliminary experiments revealed that contact with dielectric windows confounded imaging data and made it nearly impossible to deconvolve thickness variations due to contact from thickness variations due to water content variation. A follow up study with a new optical design allowed the acquisition of rabbit data and the results suggest that the observed, time varying contrast was due entirely to the water dynamics of the cornea. This paper presents the first ever in vivo images of human cornea. Five volunteers with healthy cornea were recruited and their eyes were imaged three times over the course of a few minutes with our novel imaging system. Noticeable changes in corneal reflectivity were observed and attributed to the drying of the tear film. The results suggest that clinically compatible, non-contact corneal imaging is feasible and indicate that signal acquired from non-contact imaging of the cornea is a complicated coupling of stromal water content and tear film.

  15. First steps of laparoscopic surgery in Lubumbashi: problems encountered and preliminary results.

    Science.gov (United States)

    Arung, Willy; Dinganga, Nathalie; Ngoie, Emmanuel; Odimba, Etienne; Detry, Olivier

    2015-01-01

    For many reasons, laparoscopic surgery has been performed worldwide. Due to logistical constraints its first steps occurred in Lubumbashi only in 2008. The aim of this presentation was to report authors' ten-month experience of laparoscopic surgery at Lubumbashi Don Bosco Missionary Hospital (LDBMH): problems encountered and preliminary results. The study was a transsectional descriptive work with a convenient sampling. It only took in account patients with abdominal surgical condition who consented to undergo laparoscopic surgery and when logistical constraints of the procedure were found. Independent variables were patients' demographic parameters, staff, equipments and consumable. Dependent parameters included surgical abdominal diseases, intra-operative circumstances and postoperative short term mortality and morbidity. Between 1(st)April 2009 and 28(th) February 2010, 75 patients underwent laparoscopic surgery at the LDBMH making 1.5% of all abdominal surgical activities performed at this institution. The most performed procedure was appendicectomy for acute appendicitis (64%) followed by exploratory laparoscopy for various abdominal chronic pain (9.3%), adhesiolysis for repeated periods of subacute intestinal obstruction in previously laparotomised patients (9.3%), laparoscopic cholecystectomy for post acute cholecystitis on gall stone (5.3%) and partial colectomy for symptomatic redundant sigmoid colon (2.7%). There were 4% of conversion to laparotomy. Laparoscopic surgery consumed more time than laparotomy, mostly when dealing with appendicitis. However, postoperatively, patients did quite well. There was no death in this series. Nursing care was minimal with early discharge. These results are encouraging to pursue laparoscopic surgery with DRC Government and NGO's supports. PMID:26448805

  16. Hand Robotics Rehabilitation: Feasibility and Preliminary Results of a Robotic Treatment in Patients with Hemiparesis

    Directory of Open Access Journals (Sweden)

    Patrizio Sale

    2012-01-01

    Full Text Available Background. No strongly clinical evidence about the use of hand robot-assisted therapy in stroke patients was demonstrated. This preliminary observer study was aimed at evaluating the efficacy of intensive robot-assisted therapy in hand function recovery, in the early phase after a stroke onset. Methods. Seven acute ischemic stroke patients at their first-ever stroke were enrolled. Treatment was performed using Amadeo robotic system (Tyromotion GmbH Graz, Austria. Each participant received, in addition to inpatients standard rehabilitative treatment, 20 sessions of robotic treatment for 4 consecutive weeks (5 days/week. Each session lasted for 40 minutes. The exercises were carried out as follows: passive modality (5 minutes, passive/plus modality (5 minutes, assisted therapy (10 minutes, and balloon (10 minutes. The following impairment and functional evaluations, Fugl-Meyer Scale (FM, Medical Research Council Scale for Muscle Strength (hand flexor and extensor muscles (MRC, Motricity Index (MI, and modified Ashworth Scale for wrist and hand muscles (AS, were performed at the beginning (T0, after 10 sessions (T1, and at the end of the treatment (T2. The strength hand flexion and extension performed by Robot were assessed at T0 and T2. The Barthel Index and COMP (performance and satisfaction subscale were assessed at T0 and T2. Results. Clinical improvements were found in all patients. No dropouts were recorded during the treatment and all subjects fulfilled the protocol. Evidence of a significant improvement was demonstrated by the Friedman test for the MRC (P<0.0123. Evidence of an improvement was demonstrated for AS, FM, and MI. Conclusions. This original rehabilitation treatment could contribute to increase the hand motor recovery in acute stroke patients. The simplicity of the treatment, the lack of side effects, and the first positive results in acute stroke patients support the recommendations to extend the clinical trial of this

  17. The role of apparent diffusion coefficient values in detecting testicular intraepithelial neoplasia: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Tsili, Athina C., E-mail: a_tsili@yahoo.gr [Department of Radiology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Ntorkou, Alexandra, E-mail: alexdorkou@yahoo.com [Department of Radiology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Baltogiannis, Dimitrios, E-mail: Greece.dbaltog@cc.uoi.gr [Department of Urology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Goussia, Anna, E-mail: agoussia@uoi.gr [Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Astrakas, Loukas G., E-mail: astrakas@uoi.gr [Department of Medical Physics, Medical School, University of Ioannina, 45110 Ioannina (Greece); Malamou-Mitsi, Vasiliki, E-mail: vmalamou@cc.uoi.gr [Department of Pathology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Sofikitis, Nikolaos, E-mail: akrosnin@hotmail.com [Department of Urology, Medical School, University of Ioannina, 45110 Ioannina (Greece); Argyropoulou, Maria I., E-mail: margyrop@cc.uoi.gr [Department of Radiology, Medical School, University of Ioannina, 45110 Ioannina (Greece)

    2015-05-15

    Highlights: • ADC values proved useful in the discrimination between TGCNs and normal testis. • Testicular intraepithelial neoplasia represents the precursor of most TGCNs. • ADC values cannot be used to detect testicular intraepithelial neoplasia. - Abstract: Introduction: The aim of this study is to improve detection of testicular intraepithelial neoplasia (TIN) by measurement of apparent diffusion coefficient (ADC) values. Materials and methods: Fifty-six MRI examinations of the scrotum, including 26 histologically proven testicular germ cell neoplasms were retrospectively evaluated. DWI was performed using a single shot, multi-slice spin-echo planar diffusion pulse sequence and b-values of 0 and 900 s mm{sup −2}. ADC measurements were classified into three groups according to their location: group 1 (n = 19), non-tumoral part, adjacent to testicular carcinoma, where the possible location of TIN was; group 2 (n = 26), testicular carcinoma; and group 3 (n = 60), normal testicular parenchyma. Analysis of variance (ANOVA) followed by post hoc analysis (Dunnett T3) was used for statistical purposes. Results: The mean ± s.d. of ADC values (×10{sup −3} mm{sup 2}/s) of different groups were: group 1, 1.08 ± 0.20; group 2, 0.72 ± 0.27; and group 3, 1.11 ± 0.14. ANOVA revealed differences of mean ADC between groups (F = 38.859, P < 0.001). Post hoc analysis showed differences between groups 2 and 3 (P < 0.001), groups 2 and 1 (P < 0.001), but not between groups 3 and 1 (P = 0.87). Conclusions: Based on our preliminary results, ADC values do not provide a reliable differentiation between TIN and testicular carcinoma or normal testicular parenchyma.

  18. Preliminary results from a detritiation facility dedicated to soft housekeeping waste

    Energy Technology Data Exchange (ETDEWEB)

    Lefebvre, X., E-mail: xavier.lefebvre@cea.fr [JET-EFDA, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); CEA, DEN, Cadarache DTN/STPA/LIPC, F-13108 Saint-Paul-lez-Durance (France); Trabuc, P.; Liger, K.; Perrais, C. [JET-EFDA, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); CEA, DEN, Cadarache DTN/STPA/LIPC, F-13108 Saint-Paul-lez-Durance (France); Tosti, S.; Borgognoni, F.; Santucci, A. [JET-EFDA, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Associazione ENEA-Euratom sulla Fusione, C.R. ENEA Frascati, Via E. Fermi 45, I-00044 Frascati, RM (Italy)

    2012-08-15

    Highlights: Black-Right-Pointing-Pointer The results of the first detritiation campaign of soft housekeeping are presented. Black-Right-Pointing-Pointer 120 to 150 Degree-Sign C increasing temperature reveals a strong rise of the detritiation yield. Black-Right-Pointing-Pointer Using Ar-2%O{sub 2} declassifies the sample from ILW to LLW (UK) in 18 h. Black-Right-Pointing-Pointer Carrier gas - H{sub 2} explosive risk is assessed before membrane reactor implementation. Black-Right-Pointing-Pointer The optimized conditions are Ar-2%O{sub 2} at 150 Degree-Sign C. - Abstract: Nuclear waste management has to be taken into account for fusion machine in tritium experimentations. Soft housekeeping waste is produced during both operating and dismantling phases and is contaminated by tritium under reduced (HT) and oxidized (HTO) forms. At CEA Cadarache, a lab-scaled facility has been built for soft housekeeping detritiation. The tritiated gas exhausted from the process described above is foreseen to be treated by a tubular Pd-Ag membrane reactor, for gaseous tritium recovery. Since this membrane reactor uses hydrogen as swamping gas the compatibility toward explosive hazard has to be taken into account. Then, this work presents a double objective. A first study is presented in order to identify the best conditions for the declassification of soft housekeeping waste, without tritium recovery. Experiments carried out at 120 Degree-Sign C are not efficient enough and do not allow one to choose the most efficient carrier gas. Some other tests are being currently performed at higher temperatures (150 Degree-Sign C). Moreover, due to safety issues, the use of air has to be avoided during membrane reactor implementation phase. Preliminary results obtained with hydrogen hazard-free carrier gases are also presented.

  19. The results of screening examinations of breast cancer conducted from 2004 to 2005 in Sierpc poviat

    International Nuclear Information System (INIS)

    Background: Breast cancer is one of the most common malignant neoplasms among women in Poland. 11733 new cases were registered in 2003. Well organized screening examinations are the most effective method of fighting against breast cancer. Aim of study: The main objective of this work was a preliminary analysis of a prophylactic examination programme for breast cancer in Sierpc district performed by the Independent Unit of Public Health Care Centres in Sierpc during the period of 2004 to 2005. Material and methods: The research was performed based on retrospective analysis of files obtained from the Department of Radiology of the Independent Unit of Public Health Care Centres in Sierpc. Prophylactic examination for detection of breast cancer includes physical examination of the breast as well as mammography. Results: The research includes 1291 women, most of them at age 50-55 years (57.1 years on average). City residents represent the biggest group of women. Nearly half of women had their first menstruation at the age of 14 to 15 years. The last menstruation occurred at age between 46 and 50 years old most frequently. The average number of labours was 2.3 and 2.5 during the analyzed period. The first labour occurred most frequently in women at the age of 21 to 25 years old. Most of the women never took previously and still do not take hormonal medicines. 80% of women have done breast self examination but over half of them (60.8%) did it occasionally. Breast examination done by a gynaecologist was performed in 22% of women during the last year. Breast cancer did not occur among family members in most of the analyzed women. Breast pain was the most frequent complaint. Over half of women (64.6%) previously underwent mammography. The biggest group among them (31.1%) includes women who had mammography between 2003 and 2004. Adipose glandular breast texture was detected in near half of women (43.5%). The result of mammography was normal in most analyzed women (87.1%). A

  20. The Immediate Results of Surgical Treatment of Bladder Cancer

    Directory of Open Access Journals (Sweden)

    Alexei L. Charyshkin

    2016-06-01

    Full Text Available The objective of this study was to evaluate the immediate results of the use of ureterointestinal anastomosis according to the Bricker technique at radical cystectomy (RC for bladder cancer (BC. Materials and Results: The study included 96 patients (11.5% women and 88.5% men with bladder cancer (BC, aged from 31 to 74 years (mean age 63.8±7.2, who underwent RC in the Lipetsk Regional Oncology Center, in the period from 2005 to 2014. Among the early postoperative complications, we identified dynamic ileus (16.7%, inflammatory complications of the surgical wound (12.5%, acute pyelonephritis (10.4%, and failure of ureterointestinal anastomosis (4.2%. The frequency of postoperative acute pyelonephritis corresponded to the findings of other authors. Two (2.1% patients died from early postoperative complications because of concomitant diseases (ischemic heart disease, myocardial infarction; thus, postoperative mortality in the early postoperative period was 4.2%. Chronic pyelonephritis with chronic renal failure detected in 15(15.6% patients after one year after surgery was the most frequent late postoperative complication. The stricture of ureterointestinal anastomosis in 9(9.4% patients has been eliminated through relaparotomy and resection of anastomosis. The development of urolithiasis in 12(12.5% patients after one year after surgery has required the implementation of contact lithotripsy and litholytic therapy.

  1. Estimating landslide losses - preliminary results of a seven-State pilot project

    Science.gov (United States)

    Highland, Lynn M.

    2006-01-01

    reliable information on economic losses associated with landslides. Each State survey examined the availability, distribution, and inherent uncertainties of economic loss data in their study areas. Their results provide the basis for identifying the most fruitful methods of collecting landslide loss data nationally, using methods that are consistent and provide common goals. These results can enhance and establish the future directions of scientific investigation priorities by convincingly documenting landslide risks and consequences that are universal throughout the 50 States. This report is organized as follows: A general summary of the pilot project history, goals, and preliminary conclusions from the Lincoln, Neb. workshop are presented first. Internet links are then provided for each State report, which appear on the internet in PDF format and which have been placed at the end of this open-file report. A reference section follows the reports, and, lastly, an Appendix of categories of landslide loss and sources of loss information is included for the reader's information. Please note: The Oregon Geological Survey has also submitted a preliminary report on indirect loss estimation methodology, which is also linked with the others. Each State report is unique and presented in the form in which it was submitted, having been independently peer reviewed by each respective State survey. As such, no universal 'style' or format has been adopted as there have been no decisions on which inventory methods will be recommended to the 50 states, as of this writing. The reports are presented here as information for decision makers, and for the record; although several reports provide recommendations on inventory methods that could be adopted nationwide, currently no decisions have been made on adopting a uniform methodology for the States.

  2. Breast cancer: results and side effects of radiotherapy after mastectomy

    International Nuclear Information System (INIS)

    The locoregional control is a crucial step in the achievement of a cancer cure. After mastectomy, the locoregional irradiation clearly reduces the chest wall and nodal relapses, especially with initial lesions more than 5 cm or with nodal involvement and/or large lymphatic or vascular emboli. Two recent randomized trials confirmed the benefit of well-adapted locoregional irradiation. In the Danish trial, including pre-menopausal 'high-risk' women treated by mastectomy and chemotherapy (CMF protocol), the radiotherapy reduced the locoregional relapses from 32 to 9% (P< 0.001) and increased the 10-year survival rates from 45 to 54% (P< 0.001). These results are now also confirmed in a postmenopausal group, with an increased 10-year survival rate of 36 to 45% (P< 0.001). In the Canadian trial, locoregional relapse rate decreased from 25 to 13% and 10-year survival rate increased from 56 to 65%. The meta-analysis published in 1995 by the Early Breast Cancer Trialist Collaborative Group (EBCTCG) showed only a modest benefit due to locoregional irradiation in breast cancer. However, when small trials and older trials started before 1970 are excluded due to imperfect methodologies and for inadequate irradiation techniques, the benefit of the 'modern' radiotherapy appears significant in the 7,840 patients selected in this way. Thus, since the locoregional irradiation can avoid some metastatic evolutions developed only after 'local' or 'nodal' relapse, it must be integrated in a multidisciplinary strategy. Nevertheless, this treatment must be safe and this is possible by the use of new techniques, including the definition of anatomical volumes and provisional dosimetry. The most important point concerns the treatment of the internal mammary nodes, especially when previous chemotherapy including anthracycline was performed. The use of a direct field, with at least 40% of the dose delivered by electrons in an alternating scheme, is recommended to ensure very good protection

  3. The Results of Intraoperative Radiotherapy for Stomach Cancer

    International Nuclear Information System (INIS)

    We retrospectively analyzed the long-term results of radical surgery and intraoperative radiation therapy (IORT) in patients with stomach cancer. From 1988 to 1994, 51 patients were treated with curative surgery and IORT. Postoperative external beam radiotherapy (EBRT) was administered to 30 patients, while adjuvant chemotherapy was administered to 35 patients. A dose of 15 Gy was irradiated with a 9 MeV electron beam as the IORT and a median dose of EBRT was 43.2 Gy (range, 7.2 to 45 Gy). The follow-up period ranged from 1-254 months, with a median follow-up period of 64 months. The median age of all the patients was 58 years (range, 30 to 71 years). The distribution of pathologic stage (American Joint Committee on Cancer [AJCC] 2002 tumor-note-metastasis [TNM]) was as follows: 13 stage I (25.5%), 10 stage II (19.6%), 25 stage III (49.0%), and 3 stage IV (5.9%). Distant metastases occurred in 11 patients (10 in the peritoneum and 1 in bone), including one patient with concurrent local recurrence (anastomosis site). The 5-year locoregional control, disease free survival and overall survival rates were 94.7%, 66.5%, and 51.7%, respectively. For the multivariate analysis, age, TNM stage, and EBRT were significant prognostic factors for overall survival, and only TNM stage for disease free survival. We could have achieved a high loco-regional control rate in patients with locally advanced stomach cancer by adding IORT to radical surgery. However, the benefit of IORT on survival remains to be elucidated.

  4. The Results of Intraoperative Radiotherapy for Stomach Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Ji Hoon; Kang, Min Kyu; Kim, Myung Se; Kim, Sung Kyu; Yun, Sang Mo; Kim, Sung Hoon [Dept. of Radiation Oncology, Yeungnam University College of Medicine, Daegu (Korea, Republic of)

    2010-11-15

    We retrospectively analyzed the long-term results of radical surgery and intraoperative radiation therapy (IORT) in patients with stomach cancer. From 1988 to 1994, 51 patients were treated with curative surgery and IORT. Postoperative external beam radiotherapy (EBRT) was administered to 30 patients, while adjuvant chemotherapy was administered to 35 patients. A dose of 15 Gy was irradiated with a 9 MeV electron beam as the IORT and a median dose of EBRT was 43.2 Gy (range, 7.2 to 45 Gy). The follow-up period ranged from 1-254 months, with a median follow-up period of 64 months. The median age of all the patients was 58 years (range, 30 to 71 years). The distribution of pathologic stage (American Joint Committee on Cancer [AJCC] 2002 tumor-note-metastasis [TNM]) was as follows: 13 stage I (25.5%), 10 stage II (19.6%), 25 stage III (49.0%), and 3 stage IV (5.9%). Distant metastases occurred in 11 patients (10 in the peritoneum and 1 in bone), including one patient with concurrent local recurrence (anastomosis site). The 5-year locoregional control, disease free survival and overall survival rates were 94.7%, 66.5%, and 51.7%, respectively. For the multivariate analysis, age, TNM stage, and EBRT were significant prognostic factors for overall survival, and only TNM stage for disease free survival. We could have achieved a high loco-regional control rate in patients with locally advanced stomach cancer by adding IORT to radical surgery. However, the benefit of IORT on survival remains to be elucidated.

  5. Low rectal cancer : aspects of surgical techniques and treatment results

    OpenAIRE

    Anderin, Claes

    2012-01-01

    Rectal cancer is the 7th most common form of cancer in Sweden, both for men and women. About one third of all patients diagnosed with rectal cancer have a low tumour (i.e. 0-5 cm from the anal verge). Abdominoperineal excision (APE) is the most common surgical procedure in low rectal cancer, performed in approximately 80% of patients. While oncological outcomes in rectal cancer have improved in recent decades, the outcome after APE has remained poor and local recurrence rates have been report...

  6. Factors controlling short-term soil microbial response after laboratory heating. Preliminary results

    Science.gov (United States)

    Jiménez-Compán, Elizabeth; Jiménez-Morillo, Nicasio; Jordán, Antonio; Bárcenas-Moreno, Gema

    2015-04-01

    Soil microbial response after fire is controlled by numerous variables which conclude with a mosaic of results depending on organic carbon alterations or pH fire-induced changes. This fact has complicated the studies focused on post-fire microbial response, compiling high variability of opposite result in the bibliography. Soil laboratory heating cannot emulate a real wildfire effect on soil but lead us the possibility to control several variables and it is a valid tool to clarify the relative weight of different factors controlling microbial response after soil heating. In this preliminary study different heated treatments were applied to unaltered forest soil samples, obtaining 4 different heating treatments to simulate a range of fire intensities: unaltered-control (UH), and soil heated at 300, 450 and 500 °C. In order to isolate possible nutrient availability or pH heating-induced changes, different culture media were prepared using soil:water extract from each heating treatments and adding different supplements to obtain the total of 11 different culture media: unheated soil without supplements (UH-N-), unheated soil with nutrient supplement (UH-N+), soil heated at 300 °C without supplements (300-N-), soil heated at 300 °C with nutrient supplement (300-N+), soil heated at 300 °C with nutrient supplement and pH-buffered (300-N+pH); soil heated at 450 °C without supplements (450-N-), soil heated at 450 °C with nutrient supplement (450-N+), soil heated at 450 °C with nutrient supplement and pH-buffered (450-N+); soil heated at 500 °C without supplements (500-N-), soil heated at 500 °C with nutrient supplement (500-N+), soil heated at 500 °C with nutrient supplement and pH-buffered (500-N+). Each media was inoculated with different dilutions of a microbial suspension from the original unaltered soil, and the abundance of viable and cultivable microorganisms were measured by plate count method. In addition, the analysis of heating-induced soil organic

  7. GPS Sounding of the Atmosphere from Low Earth Orbit: Preliminary Results.

    Science.gov (United States)

    Ware, R.; Rocken, C.; Solheim, F.; Exner, M.; Schreiner, W.; Anthes, R.; Feng, D.; Herman, B.; Gorbunov, M.; Sokolovskiy, S.; Hardy, K.; Kuo, Y.; Zou, X.; Trenberth, K.; Meehan, T.; Melbourne, W.; Businger, S.

    1996-01-01

    This paper provides an overview of the methodology of and describes preliminary results from an experiment called GPS/MET (Global Positioning System/Meteorology), in which temperature soundings are obtained from a low Earth-orbiting satellite using the radio occultation technique. Launched into a circular orbit of about 750-km altitude and 70° inclination on 3 April 1995, a small research satellite, MicroLab 1, carried a laptop-sized radio receiver. Each time this receiver rises and sets relative to the 24 operational GPS satellites, the GPS radio waves transect successive layers of the atmosphere and are bent (refracted) by the atmosphere before they reach the receiver, causing a delay in the dual-frequency carrier phase observations sensed by the receiver. During this occultation, GPS limb sounding measurements are obtained from which vertical profiles of atmospheric refractivity can be computed. The refractivity is a function of pressure, temperature, and water vapor and thus provides information on these variables that has the potential to be useful in weather prediction and weather and climate research.Because of the dependence of refractivity on both temperature and water vapor, it is generally impossible to compute both variables from a refractivity sounding. However, if either temperature or water vapor is known from independent measurements or from model predictions, the other variable may be calculated. In portions of the atmosphere where moisture effects are negligible (typically above 5-7 km), temperature may be estimated directly from refractivity.This paper compares a representative sample of 11 temperature profiles derived from GPS/MET soundings (assuming a dry atmosphere) with nearby radiosonde and high-resolution balloon soundings and the operational gridded analysis of the National Centers for Environmental Prediction (formerly the National Meteorological Center). One CPS/MET profile was obtained at a location where a temperature profile from the

  8. {sup 18}F-FDG positron emission tomography in the early diagnosis of enterocolitis: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Kresnik, E.; Gallowitsch, H.J.; Igerc, I.; Kumnig, G.; Gomez, I.; Lind, P. [Nuclear Medicine and Special Endocrinology, PET Centre, General Hospital, St. Veiterstrasse 47, 9020 Klagenfurt (Austria); Mikosch, P.; Alberer, D.; Hebenstreit, A. [Department of Internal Medicine and Gastroenterology, General Hospital, Klagenfurt (Austria); Wuertz, F. [Department of Pathology, General Hospital, Klagenfurt (Austria); Kogler, D.; Gasser, J. [Department of Radiology, General Hospital, Klagenfurt (Austria)

    2002-10-01

    Collagenous and eosinophilic colitis are rare diseases characterised by chronic watery diarrhoea. Radiographic evaluation of the gastrointestinal tract and colonoscopy are usually non-diagnostic since as many as one-third of patients will have minor abnormalities. To date a few investigators have reported increased fluorine-18 fluorodeoxyglucose ({sup 18}F-FDG) uptake on positron emission tomography (PET) in patients with acute enterocolitis, but there have been no reports on the use of {sup 18}F-FDG PET for the diagnosis of collagenous or eosinophilic colitis in an early clinical stage. The aim of this preliminary study was to evaluate the usefulness of {sup 18}F-FDG PET in the early diagnosis of patients with colitis. We investigated five women (mean age 61.2{+-}12.1 years) who had been diagnosed as having colitis in an early clinical stage. In all but one of the patients, the diagnosis of colitis was based on biopsy. Magnetic resonance colonography, ultrasonography and colonoscopy were performed in all but one of the patients. Two women were identified as having collagenous colitis in an early clinical stage. Another two patients had eosinophilic colitis. The morphological imaging methods, magnetic resonance colonography and ultrasonography, yielded no suspicious findings, and the results of colonoscopy similarly showed no abnormalities. One patient had colitis due to bacterial infection. In all patients {sup 18}F-FDG PET showed a pathological increase in tracer uptake in the large bowel, suggestive of colitis. In four of the five patients, colitis was confirmed by histology, and in one, by bacterial analysis. {sup 18}F-FDG PET was able to detect colitis in an early clinical stage, when morphological imaging methods and colonoscopy were non-diagnostic. The early performance of {sup 18}F-FDG PET imaging in patients with possible colitis is encouraging. (orig.)

  9. Work-nonwork interference: Preliminary results on the psychometric properties of a new instrument

    Directory of Open Access Journals (Sweden)

    Eileen Koekemoer

    2010-03-01

    Full Text Available Orientation: Recently, a new work-nonwork interference instrument was developed to measure the interference between work and nonwork roles in the South African context (Koekemoer, Mostert & Rothmann, 2010. However, no information is available on the psychometric properties of this instrument.Research purpose: The objectives of this study were to investigate the internal validity (construct, discriminant and convergent validity, reliability and external validity (relationship with theoretically relevant variables, including job characteristics, home characteristics, burnout, ill health and life satisfaction of the instrument.Motivation for the study: Work-family interaction is a key topic receiving significant research attention. In order to facilitate comparison across work-family studies, the use of psychometrically sound instruments is of great importance.Research design, approach and method: A cross-sectional survey design was used for the target population of married employees with children working at a tertiary institution in the North West province (n = 366. In addition to the new instrument, job characteristics, home characteristics, burnout, ill health and life satisfaction were measured.Main findings: The results provided evidence for construct, discriminant and convergent validity, reliability and significant relations with external variables.Practical/managerial implications: The new instrument can be used by researchers and managers as a test under development to investigate the interference between work and different nonwork roles (i.e. parental role, spousal role, work role, domestic role and specific relations with antecedents (e.g. job/home characteristics and well-being (e.g. burnout, ill health and life satisfaction.Contribution/value-add: This study provides preliminary information on the psychometric properties of a new instrument that measures the interference between work and nonwork.

  10. Preliminary results of the Source China Sea passive source OBS array experiment

    Science.gov (United States)

    Yang, T.; Liu, C.; Pei, Y.; Xia, S.

    2013-12-01

    The Scarborough, or Huangyan, Seamount chain in South China Sea (SCS) represents an extreme case of the global mid-ocean ridge system where the magmatism continues for many million years after the cessation of spreading. To understand this unique process, the South China Sea Deep (SCSD) program funded an experiment deploying a passive source OBS array to image the lithospheric structure beneath the extinct ridge. In April 2012, 18 passive source OBSs, including 15 Guralp CMG-40T OBS and 3 I-4C OBS, were deployed around the Huangyan Island for one year. 11 OBSs were successfully recovered this April, and their data are being processed. Here we present some preliminary results from analyses of this dataset, including the general quality of three-component seismograms, characteristics of seafloor ambient noise spectra, determining the OBS orientation from the Rayleigh wave polarization, and the dispersion analysis of Rayleigh waves. We found that, for most stations, seismograms from teleseismic, regional and local events are generally good with the horizontal records being comparable with vertical component. The noise levels in these seafloor stations are much higher than land-based stations, especially in shorter periods, likely suggesting the direct and stronger impact from the tempestuous SCS. Applications of more sophisticated seismic techniques such as surface wave tomography, seismic anisotropy, receiver function and ambient noise cross-correlation are underway. In addition to the low recovery rate, there are other lessons learned from this experiment. For example, at least two stations have detectable timing problems; Airgun shots should have been used to constrain the timings and orientations in both deployment and recovery. It is still challenging and costly to carry out long-term passive source seismic observations in deep sea.

  11. Paleomagnetism of the Todos Santos Formation in the Maya Block, Chiapas, Mexico: Preliminary Results

    Science.gov (United States)

    Godinez-Urban, A.; Molina-Garza, R. S.; Iriondo, A.; Geissman, J. W.

    2008-12-01

    Preliminary results of a paleomagnetic study on jurassic volcanic rocks (U-Pb 188.8 +/- 3.2Ma) locally interbedded with red beds assigned to the Todos Santos Formation, sampled in the Homoclinal Tectonic Province of the Neogene Fold Belt, Chiapas-Mexico, reveal multi component magnetizations acquired during pre- and post- folding of these rocks. The samples responded well to thermal demagnetization, but not so to AF demagnetization, suggesting that a high coercivity mineral phase like hematite is the main remanence carrier. The post-folding B-component direction of Dec=174.3 Inc=-30.6 (k=46; alpha95=13.6; N=4) represents a recent Tertiary? overprint; while the pre-folding C-component direction of Dec=329.9 Inc=7.8 (k=12.5; alpha95=16.3; N=8) is in agreement with a previously reported small data set for the Todos Santos Formation. When compared to the North American reference direction (Jurassic Kayenta Formation) the observed direction indicates a counterclockwise rotation of 35.9 +/- 16.6 degrees, and moderate north to south latitudinal displacement. If a reference pole from NE North America is used, the amount of counterclockwise rotation and latitudinal displacement are both slightly reduced. If the assumption that Jurassic strata in Chiapas reflect displacement of the Maya Block, then these data are consistent with reconstructions of the Maya Block in the Gulf of Mexico region. Other sites sampled in Jurassic strata suggest that in addition to the interpreted regional rotation, local (vertical-axis) rotations may have affected the region in more recent times.

  12. The preliminary results: Internal seismic velocity structure imaging beneath Mount Lokon

    International Nuclear Information System (INIS)

    Historical records that before the 17th century, Mount Lokon had been dormant for approximately 400 years. In the years between 1350 and 1400, eruption ever recorded in Empung, came from Mount Lokon’s central crater. Subsequently, in 1750 to 1800, Mount Lokon continued to erupt again and caused soil damage and fall victim. After 1949, Mount Lokon dramatically increased in its frequency: the eruption interval varies between 1 – 5 years, with an average interval of 3 years and a rest interval ranged from 8 – 64 years. Then, on June 26th, 2011, standby alert set by the Center for Volcanology and Geological Hazard Mitigation. Peak activity happened on July 4th, 2011 that Mount Lokon erupted continuously until August 28th, 2011. In this study, we carefully analyzed micro-earthquakes waveform and determined hypocenter location of those events. We then conducted travel time seismic tomographic inversion using SIMULPS12 method to detemine Vp, Vs and Vp/Vs ratio structures beneath Lokon volcano in order to enhance our subsurface geological structure. During the tomographic inversion, we started from 1-D seismic velocities model obtained from VELEST33 method. Our preliminary results show low Vp, low Vs, and high Vp/Vs are observed beneath Mount Lokon-Empung which are may be associated with weak zone or hot material zones. However, in this study we used few station for recording of micro-earthquake events. So, we suggest in the future tomography study, the adding of some seismometers in order to improve ray coverage in the region is profoundly justified

  13. Investigation of psychophysical measure for evaluation of similar images for mammographic masses: Preliminary results

    International Nuclear Information System (INIS)

    We investigated a psychophysical similarity measure for selection of images similar to those of unknown masses on mammograms, which may assist radiologists in the distinction between benign and malignant masses. Sixty pairs of masses were selected from 1445 mass images prepared for this study, which were obtained from the Digital Database for Screening Mammography by the University of South Florida. Five radiologists provided subjective similarity ratings for these 60 pairs of masses based on the overall impression for diagnosis. Radiologists' subjective ratings were marked on a continuous rating scale and quantified between 0 and 1, which correspond to pairs not similar at all and pairs almost identical, respectively. By use of the subjective ratings as 'gold standard', similarity measures based on the Euclidean distance between pairs in feature space and the psychophysical measure were determined. For determination of the psychophysical similarity measure, an artificial neural network (ANN) was employed to learn the relationship between radiologists' average subjective similarity ratings and computer-extracted image features. To evaluate the usefulness of the similarity measures, the agreement with the radiologists' subjective similarity ratings was assessed in terms of correlation coefficients between the average subjective ratings and the similarity measures. A commonly used similarity measure based on the Euclidean distance was moderately correlated (r=0.644) with the radiologists' average subjective ratings, whereas the psychophysical measure by use of the ANN was highly correlated (r=0.798). The preliminary result indicates that a psychophysical similarity measure would be useful in the selection of images similar to those of unknown masses on mammograms

  14. Raising future forensic pathologists (first report): results of a preliminary questionnaire survey.

    Science.gov (United States)

    Murakami, Manabu; Matoba, Kotaro; Terazawa, Koichi

    2012-08-01

    The shortage of future forensic pathologists is a serious problem both in Japan and overseas. In Japan, however, factors such as government budget cuts and increasing the autopsy rates, make the condition even worse. In an attempt to improve this situation, we implemented a questionnaire survey to investigate the particular features necessary when selecting a career in forensic medicine. As a preliminary study, we sent the questionnaire along with an anonymous answer sheet to all forensic pathologists with a degree in medicine M.D., who were affiliated with universities in Hokkaido and the Tohoku district of Japan as of August 2011. Thirteen physicians in nine universities (response rate 77.8%) returned the answer sheet. Characteristics of participants are listed below: years of experience, board specialty and number of years as board certified specialists, percentage of work effort spent on autopsy practice, the time when they decided to work as a forensic pathologist, the time when to best recommend forensic pathologist as a career, and crucial factors in choosing the specialty of forensic medicine. As a result of this research, we've revealed the importance of undergraduate medical education or the effect on the role models. Furthermore, we've also extracted miscellaneous comments, such as standardization of minimum requirements. In our study, we' ve found some clues to increase future candidates in the field forensic medicine. However, we must collect further samples for our questionnaire survey to validate the study, and, as a future project, we must also address this problem at the congress of forensic medicine. PMID:23016267

  15. Preliminary Results from Electric Arc Furnace Off-Gas Enthalpy Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Nimbalkar, Sachin U [ORNL; Thekdi, Arvind [E3M Inc; Keiser, James R [ORNL; Storey, John Morse [ORNL

    2015-01-01

    This article describes electric arc furnace (EAF) off-gas enthalpy models developed at Oak Ridge National Laboratory (ORNL) to calculate overall heat availability (sensible and chemical enthalpy) and recoverable heat values (steam or power generation potential) for existing EAF operations and to test ORNL s new EAF waste heat recovery (WHR) concepts. ORNL s new EAF WHR concepts are: Regenerative Drop-out Box System and Fluidized Bed System. The two EAF off-gas enthalpy models described in this paper are: 1.Overall Waste Heat Recovery Model that calculates total heat availability in off-gases of existing EAF operations 2.Regenerative Drop-out Box System Model in which hot EAF off-gases alternately pass through one of two refractory heat sinks that store heat and then transfer it to another gaseous medium These models calculate the sensible and chemical enthalpy of EAF off-gases based on the off-gas chemical composition, temperature, and mass flow rate during tap to tap time, and variations in those parameters in terms of actual values over time. The models provide heat transfer analysis for the aforementioned concepts to confirm the overall system and major component sizing (preliminary) to assess the practicality of the systems. Real-time EAF off-gas composition (e.g., CO, CO2, H2, and H2O), volume flow, and temperature data from one EAF operation was used to test the validity and accuracy of the modeling work. The EAF off-gas data was used to calculate the sensible and chemical enthalpy of the EAF off-gases to generate steam and power. The article provides detailed results from the modeling work that are important to the success of ORNL s EAF WHR project. The EAF WHR project aims to develop and test new concepts and materials that allow cost-effective recovery of sensible and chemical heat from high-temperature gases discharged from EAFs.

  16. Repetitive transcranial magnetic stimulation as an adjuvant method in the treatment of depression: Preliminary results

    Directory of Open Access Journals (Sweden)

    Jovičić Milica

    2014-01-01

    Full Text Available Introduction. Repetitive transcranial magnetic stimulation (rTMS is a method of brain stimulation which is increasingly used in both clinical practice and research. Up-to-date studies have pointed out a potential antidepressive effect of rTMS, but definitive superiority over placebo has not yet been confirmed. Objective. The aim of the study was to examine the effect of rTMS as an adjuvant treatment with antidepressants during 18 weeks of evaluation starting from the initial application of the protocol. Methods. Four patients with the diagnosis of moderate/severe major depression were included in the study. The protocol involved 2000 stimuli per day (rTMS frequency of 10 Hz, intensity of 120% motor threshold administered over the left dorsolateral prefrontal cortex (DLPFC for 15 days. Subjective and objective depressive symptoms were measured before the initiation of rTMS and repeatedly evaluated at week 3, 6, 12 and 18 from the beginning of the stimulation. Results. After completion of rTMS protocol two patients demonstrated a reduction of depressive symptoms that was sustained throughout the 15-week follow-up period. One patient showed a tendency of remission during the first 12 weeks of the study, but relapsed in week 18. One patient showed no significant symptom reduction at any point of follow-up. Conclusion. Preliminary findings suggest that rTMS has a good tolerability and can be efficient in accelerating the effect of antidepressants, particularly in individuals with shorter duration of depressive episodes and moderate symptom severity. [Projekat Ministarstva nauke Republike Srbije, br. III41029 i br. ON175090

  17. Preliminary results of phase I/II study of simultaneous modulated accelerated (SMART) for nasopharyngeal carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jin Hong; Lee, Sang Wook; Back, Geum Mun [College of Medicine, University of Ulsan, Asan Medical Center, Seoul (Korea, Republic of)] (and others)

    2006-03-15

    To present preliminary results of intensity-modulated radiotherapy (IMRT) using the simultaneous modulated accelerated radiation therapy (SMART) boost technique in patients with nasopharyngeal carcinoma (NPC). Twenty patients who underwent IMRT for non-metastatic NPC at the Asan Medical Center between September 2001 and December 2003 were prospectively evaluated. IMRT was delivered using the 'step and shoot' SMART technique at prescribed doses of 72 Gy (2.4 Gy/day) to the gross tumor volume (GTV), 60 Gy (2 Gy/day) to the clinical target volume (CTV) and metastatic nodal station, and 46 Gy (2 Gy/day) to the clinically negative neck region. Eighteen patients also received concurrent chemotherapy using cisplatin once per week. The median follow-up period was 27 months. Nineteen patients completed the treatment without interruption; the remaining patient interrupted treatment for 2 weeks owing to severe pharyngitis and malnutrition. Five patients (25%) had RTOG grade 3 mucositis, whereas nine (45%) had grade 3 pharyngitis. Seven patients (35%) lost more than 10% of their pretreatment weight, whereas 11 (55%) required intravenous fluids and/or tube feeding. There was no grade 3 or 4 chronic xerostomia. All patients showed complete response. Two patients had distant metastases and loco-regional recurrence, respectively. IMRT using the SMART boost technique allows parotid sparing, as shown clinically and by dosimetry, and may also be more effective biologically. A larger population of patients and a longer follow-up period are needed to evaluate ultimate tumor control and late toxicity.

  18. Wageningen Urban Rainfall Experiment 2014 (WURex14): Experimental setup and preliminary results

    Science.gov (United States)

    van Leth, Thomas C.; Uijlenhoet, Remko; Overeem, Aart; Leijnse, Hidde; Hazenberg, Pieter; Berne, Alexis

    2016-04-01

    the preliminary results.

  19. Scintigraphic test of gastric emptying and motility: preliminary results in patients with chronic gastritis

    Energy Technology Data Exchange (ETDEWEB)

    Hausmann, T. [Abt. Nuklearmedizin und Spezielle Biophysik, Medizinische Hochschule Hannover (Germany); Mueller-Schauenburg, W. [Abt. Nuklearmedizin, Univ. Tuebingen (Germany); Goeke, M. [Abt. Gastroenterologie und Hepatologie, Medizinische Hochschule Hannover (Germany); Luebeck, M. [Abt. Nuklearmedizin, Univ.-Krankenhaus Eppendorf, Hamburg (Germany); Gratz, K.F. [Abt. Nuklearmedizin und Spezielle Biophysik, Medizinische Hochschule Hannover (Germany); Meier, P. [Abt. Gastroenterologie und Hepatologie, Medizinische Hochschule Hannover (Germany); Manns, M. [Abt. Gastroenterologie und Hepatologie, Medizinische Hochschule Hannover (Germany); Hundeshagen, H. [Abt. Nuklearmedizin und Spezielle Biophysik, Medizinische Hochschule Hannover (Germany)

    1995-11-01

    To record gastric peristalsis using a conventional scintigraphic gastric emptying test the frame rate was increased to 1 frame per 3 s at 10, 30, and 50 min postprandially. The gastric contraction frequency was obtained from the first harmonic of a Fourier transform of a gastric region of interest (ROI) curve. The propagation of gastric contractions was better revealed from computed functional images of the phase and amplitude distribution as compared with the multiple scintigraphic images. The maximal count-rate changes per pixel were calculated as an estimate of the most prominent regional contractile activity of the gastric wall. Among 12 patients with chronic gastritis the group with more severe dyspeptic complaints (n = 6) had significantly higher count-rate changes per pixel when compared with the group with minor complaints (20.0, 21.1 and 14.2 vs 12.9, 12.0, and 10.4 counts/pixel X s at 10, 30, and 50 min. respectively; p < 0.05). The mean half-times of gastric emptying (61, SD 11 vs 54, SD 13 min) and the mean gastric contraction frequencies (2.99, SD 0.19; 3.09, SD 0.33; 3.07, SD 0.10 vs 3.15, SD 0.15; 3.17, SD 0.13; 3.23, SD 0.20 cycles/min at 10, 30, and 50 min, respectively) did not show significant differences between both groups. Our preliminary results agree with the hypothesis of the occurrence of more powerful, nonexpulsive gastric-wall contractions in patients with more severe dyspeptic complaints. Hence, additional quantification of gastric motility allowed a more detailed evaluation of gastric-motor-activity disorders that were for so long not accessible to conventional gastric-emptying tests. (orig.)

  20. The preliminary results: Internal seismic velocity structure imaging beneath Mount Lokon

    Energy Technology Data Exchange (ETDEWEB)

    Firmansyah, Rizky, E-mail: rizkyfirmansyah@hotmail.com [Geophysical Engineering, Faculty of Mining and Petroleum Engineering, Institut Teknologi Bandung, Bandung, 40132 (Indonesia); Nugraha, Andri Dian, E-mail: nugraha@gf.itb.ac.id [Global Geophysical Group, Faculty of Mining and Petroleum Engineering, Institut Teknologi Bandung, Bandung, 40132 (Indonesia); Kristianto, E-mail: kris@vsi.esdm.go.id [Center for Volcanology and Geological Hazard Mitigation (CVGHM), Geological Agency, Bandung, 40122 (Indonesia)

    2015-04-24

    Historical records that before the 17{sup th} century, Mount Lokon had been dormant for approximately 400 years. In the years between 1350 and 1400, eruption ever recorded in Empung, came from Mount Lokon’s central crater. Subsequently, in 1750 to 1800, Mount Lokon continued to erupt again and caused soil damage and fall victim. After 1949, Mount Lokon dramatically increased in its frequency: the eruption interval varies between 1 – 5 years, with an average interval of 3 years and a rest interval ranged from 8 – 64 years. Then, on June 26{sup th}, 2011, standby alert set by the Center for Volcanology and Geological Hazard Mitigation. Peak activity happened on July 4{sup th}, 2011 that Mount Lokon erupted continuously until August 28{sup th}, 2011. In this study, we carefully analyzed micro-earthquakes waveform and determined hypocenter location of those events. We then conducted travel time seismic tomographic inversion using SIMULPS12 method to detemine Vp, Vs and Vp/Vs ratio structures beneath Lokon volcano in order to enhance our subsurface geological structure. During the tomographic inversion, we started from 1-D seismic velocities model obtained from VELEST33 method. Our preliminary results show low Vp, low Vs, and high Vp/Vs are observed beneath Mount Lokon-Empung which are may be associated with weak zone or hot material zones. However, in this study we used few station for recording of micro-earthquake events. So, we suggest in the future tomography study, the adding of some seismometers in order to improve ray coverage in the region is profoundly justified.

  1. Canadian Experiment for Soil Moisture in 2010 (CanEX-SM10): Overview and Preliminary Results

    Science.gov (United States)

    Magagi, Ramata; Berg, Aaron; Goita, Kalifa; Belair, Stephane; Jackson, Tom; Toth, B.; Walker, A.; McNairn, H.; O'Neill, P.; Moghdam. M; Gherboudj, Imen; Colliander, A.; Cosh, M.; Belanger, John; Burgin, M.; Fisher, J.; Kim, S.; Rousseau, L-P B.; Djamai, N.; Shang, J.; Merzouki, A.

    2011-01-01

    The Canadian Experiment for Soil Moisture in 2010 (CanEx-SM10) was carried out in Saskatchewan, Canada from 31 May to 16 June, 2010. Its main objective was to contribute to Soil Moisture and Ocean salinity (SMOS) mission validation and the pre-launch assessment of Soil Moisture and Active and Passive (SMAP) mission. During CanEx-SM10, SMOS data as well as other passive and active microwave measurements were collected by both airborne and satellite platforms. Ground-based measurements of soil (moisture, temperature, roughness, bulk density) and vegetation characteristics (Leaf Area Index, biomass, vegetation height) were conducted close in time to the airborne and satellite acquisitions. Besides, two ground-based in situ networks provided continuous measurements of meteorological conditions and soil moisture and soil temperature profiles. Two sites, each covering 33 km x 71 km (about two SMOS pixels) were selected in agricultural and boreal forested areas in order to provide contrasting soil and vegetation conditions. This paper describes the measurement strategy, provides an overview of the data sets and presents preliminary results. Over the agricultural area, the airborne L-band brightness temperatures matched up well with the SMOS data. The Radio frequency interference (RFI) observed in both SMOS and the airborne L-band radiometer data exhibited spatial and temporal variability and polarization dependency. The temporal evolution of SMOS soil moisture product matched that observed with the ground data, but the absolute soil moisture estimates did not meet the accuracy requirements (0.04 m3/m3) of the SMOS mission. AMSR-E soil moisture estimates are more closely correlated with measured soil moisture.

  2. Photodynamic therapy for locally advanced pancreatic cancer: early clinical results

    Science.gov (United States)

    Sandanayake, N. S.; Huggett, M. T.; Bown, S. G.; Pogue, B. W.; Hasan, T.; Pereira, S. P.

    2010-02-01

    Pancreatic adenocarcinoma ranks as the fourth most common cause of cancer death in the USA. Patients usually present late with advanced disease, limiting attempted curative surgery to 10% of cases. Overall prognosis is poor with one-year survival rates of less than 10% with palliative chemotherapy and/or radiotherapy. Given these dismal results, a minimally invasive treatment capable of local destruction of tumor tissue with low morbidity may have a place in the treatment of this disease. In this paper we review the preclinical photodynamic therapy (PDT) studies which have shown that it is possible to achieve a zone of necrosis in normal pancreas and implanted tumour tissue. Side effects of treatment and evidence of a potential survival advantage are discussed. We describe the only published clinical study of pancreatic interstitial PDT, which was carried out by our group (Bown et al Gut 2002), in 16 patients with unresectable locally advanced pancreatic adenocarcinoma. All patients had evidence of tumor necrosis on follow-up imaging, with a median survival from diagnosis of 12.5 months. Finally, we outline a phase I dose-escalation study of verteporfin single fibre PDT followed by standard gemcitabine chemotherapy which our group is currently undertaking in patients with locally advanced pancreatic cancer. Randomized controlled studies are also planned.

  3. Cosmetic results of conservative treatment for early breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bo Kyoung; Shin, Seong Soo; Kim, Seong Deok; Ha, Sung Whan; Noh, Dong Young [College of Medicine, Seoul National Univ., Seoul (Korea, Republic of)

    2001-03-01

    This study was performed to evaluate the cosmetic outcome of conservative treatment for early breast cancer and to analyze the factors influencing cosmetic outcome. From February 1992 through January 1997, 120 patients with early breast cancer were treated with conservative surgery and postoperative radiotherapy. The types of conservative surgery were quadrantectomy and axillary node dissection for 108 patients (90%) and lumpectomy or excisional biopsy for 10 patients (8.3%). Forty six patients (38%) received adjuvant chemotherapy (CMF or CAF). Cosmetic result evaluation was carried out between 16 and 74 months (median, 33 months) after surgery. The cosmetic results were classified into four categories, i.e., excellent, good, fair, and poor. The appearances of the patients' breasts were also analyzed for symmetry using the differences in distances from the stemal notch to right and left nipples. A logistic regression analysis was performed to identify independent variables influencing the cosmetic outcome. Cosmetic score was excellent or good in 76% (91/120), fair in 19% (23/120) and poor in 5% (6/ 120) of the patients. Univariate analysis showed that tumor size (T1 versus T2) (p=0.04), axillary node status (NO versus N1) (p=0.0002), extent of surgery (quadrantectomy versus lumpectomy or excisional biopsy) (p=0.02), axillary node irradiation (p=0.0005) and chemotherapy (p=0,0001) affected cosmetic score. Multivariate analysis revealed that extent of surgery (p=0.04) and chemotherapy (p=0.0002) were significant factors. For breast symmetry, univariate analysis confirmed exactly the same factors as above. Multivariate analysis revealed that tumor size (p=0.003) and lymph node status (p=0.007) affected breast symmetry. Conservative surgery and postoperative radiotherapy resulted in excellent or good cosmetic outcome in a large portion of the patients. Better cosmetic results were achieved generally in the group of patients with smaller tumor size, without

  4. Cosmetic results of conservative treatment for early breast cancer

    International Nuclear Information System (INIS)

    This study was performed to evaluate the cosmetic outcome of conservative treatment for early breast cancer and to analyze the factors influencing cosmetic outcome. From February 1992 through January 1997, 120 patients with early breast cancer were treated with conservative surgery and postoperative radiotherapy. The types of conservative surgery were quadrantectomy and axillary node dissection for 108 patients (90%) and lumpectomy or excisional biopsy for 10 patients (8.3%). Forty six patients (38%) received adjuvant chemotherapy (CMF or CAF). Cosmetic result evaluation was carried out between 16 and 74 months (median, 33 months) after surgery. The cosmetic results were classified into four categories, i.e., excellent, good, fair, and poor. The appearances of the patients' breasts were also analyzed for symmetry using the differences in distances from the stemal notch to right and left nipples. A logistic regression analysis was performed to identify independent variables influencing the cosmetic outcome. Cosmetic score was excellent or good in 76% (91/120), fair in 19% (23/120) and poor in 5% (6/ 120) of the patients. Univariate analysis showed that tumor size (T1 versus T2) (p=0.04), axillary node status (NO versus N1) (p=0.0002), extent of surgery (quadrantectomy versus lumpectomy or excisional biopsy) (p=0.02), axillary node irradiation (p=0.0005) and chemotherapy (p=0,0001) affected cosmetic score. Multivariate analysis revealed that extent of surgery (p=0.04) and chemotherapy (p=0.0002) were significant factors. For breast symmetry, univariate analysis confirmed exactly the same factors as above. Multivariate analysis revealed that tumor size (p=0.003) and lymph node status (p=0.007) affected breast symmetry. Conservative surgery and postoperative radiotherapy resulted in excellent or good cosmetic outcome in a large portion of the patients. Better cosmetic results were achieved generally in the group of patients with smaller tumor size, without axillary

  5. Preliminary study on association between toxoplasmosis and breast cancer in Iran

    Institute of Scientific and Technical Information of China (English)

    Narges; Kalantari; Salman; Ghaffari; Masomeh; Bayani; Maryam; Mitra; Elmi; Daryush; Moslemi; Novin; Nikbakhsh; Fariedh; Ghavipanjeh

    2015-01-01

    Objective:To investigate the possible association between Toxoplasma gondii(T.gondii)infection and breast cancer by examining the seropositivity and serointensity rate of anti-T gondii antibodies in breast cancer patients and healthy volunteers.Methods:This study was carried out on 66 women with breast cancer which consists of 29 newly diagnosed patients(Group 1) and 37 cases undergoing treatment and regular checkups(Group 2).Also,60 healthy women(Group 3) with no history of cancer confirmed by clinical examination and imaging participated in this study.The participants were tested for T.gondii immunoglobulin G(IgG) and immunoglobulin M(IgM) antibodies by enzyme-linked immunoassays.Results:The mean age of Groups 1.2 and 3 were 43.3±6.8,41.8±5.5 and 42.3±4.9.respectively(P=0.72).Overall.104(82.5%) and 8(6.3%) out of 126 women were positive for anti-T gondii IgG and IgM antibodies,respectively.Higher seropositivity rate of anti-T.gondii antibodies(IgG) was seen in breast cancer patients(86.4%) compared with control group(78.3%)(P=0.24).IgG antibodies were detected in 89.2%of cancer patients under treatment.82.7%of newly diagnosed patients(P=0.18).IgM antibodies were found in 3(10.3%),2(5.4%)and 3(5%) in Groups 1.2 and 3.No significant difference was found between the mean titers of T.gondii IgG antibody among these groups(P=0.87).Conclusions:This study did not find any significant association between toxoplasmosis and breast cancer besides higher rates of seropositivity and serointensity in patients compared with healthy volunteers.

  6. Leptin/HER2 crosstalk in breast cancer: in vitro study and preliminary in vivo analysis

    International Nuclear Information System (INIS)

    Obesity in postmenopausal women is associated with increased breast cancer risk, development of more aggressive tumors and resistance to certain anti-breast cancer treatments. Some of these effects might be mediated by obesity hormone leptin, acting independently or modulating other signaling pathways. Here we focused on the link between leptin and HER2. We tested if HER2 and the leptin receptor (ObR) can be coexpressed in breast cancer cell models, whether these two receptors can physically interact, and whether leptin can transactivate HER2. Next, we studied if leptin/ObR can coexist with HER2 in breast cancer tissues, and if presence of these two systems correlates with specific clinicopathological features. Expression of ObR, HER2, phospo-HER2 was assessed by immonoblotting. Physical interactions between ObR and HER2 were probed by immunoprecipitation and fluorescent immunostaining. Expression of leptin and ObR in breast cancer tissues was detected by immunohistochemistry (IHC). Associations among markers studied by IHC were evaluated using Fisher's exact test for count data. HER2 and ObR were coexpressed in all studied breast cancer cell lines. In MCF-7 cells, HER2 physically interacted with ObR and leptin treatment increased HER2 phosphorylation on Tyr 1248. In 59 breast cancers, the presence of leptin was correlated with ObR (the overall association was about 93%). This result was confirmed both in HER2-positive and in HER2-negative subgroups. The expression of leptin or ObR was numerically more frequent in larger (> 10 mm) tumors. Coexpression of HER2 and the leptin/ObR system might contribute to enhanced HER2 activity and reduced sensitivity to anti-HER2 treatments

  7. 78 FR 34340 - Welded Carbon Steel Standard Pipe and Tube Products From Turkey: Preliminary Results of...

    Science.gov (United States)

    2013-06-07

    ... Order; Welded Carbon Steel Standard Pipe and Tube Products from Turkey, 51 FR 17784 (May 15, 1986). The... International Trade Administration Welded Carbon Steel Standard Pipe and Tube Products From Turkey: Preliminary... antidumping duty order on welded carbon steel standard pipe and tube products (welded pipe and tube)...

  8. 77 FR 46386 - Certain Pasta From Turkey: Preliminary Results of Countervailing Duty Administrative Review

    Science.gov (United States)

    2012-08-03

    ... (``Pasta'') From Turkey, 60 FR 53747, 53749 (October 17, 1995) (``Preliminary Determination''), unchanged in Final Affirmative Countervailing Duty Determination: Certain Pasta (``Pasta'') from Turkey, 61 FR...; Opportunity To Request Administrative Review, 76 FR 38609 (July 1, 2011). \\2\\ See Letter from Marsan,...

  9. 78 FR 48143 - Polyethylene Terephthalate Film, Sheet, and Strip From India: Preliminary Results of Antidumping...

    Science.gov (United States)

    2013-08-07

    ... International Trade Administration Polyethylene Terephthalate Film, Sheet, and Strip From India: Preliminary... conducting an administrative review of the antidumping duty order on polyethylene terephthalate film, sheet, and strip (PET Film) from India. The period of review (POR) is July 1, 2011, through June 30,...

  10. 75 FR 81570 - Polyethylene Terephthalate Film, Sheet, and Strip From India: Preliminary Results of Antidumping...

    Science.gov (United States)

    2010-12-28

    ... International Trade Administration Polyethylene Terephthalate Film, Sheet, and Strip From India: Preliminary... semiannual new shipper review (NSR) under the antidumping duty order on polyethylene terephthalate film, sheet, and strip (PET film) from India in response to a request from SRF Limited (SRF). The...

  11. 78 FR 48651 - Polyethylene Terephthalate Film, Sheet, and Strip From Taiwan; Preliminary Results of Antidumping...

    Science.gov (United States)

    2013-08-09

    ... International Trade Administration Polyethylene Terephthalate Film, Sheet, and Strip From Taiwan; Preliminary... conducting an administrative review of the antidumping duty order on polyethylene terephthalate film, sheet, and strip (PET Film) from Taiwan. The period of review (POR) is July 1, 2011, through June 30,...

  12. 78 FR 50029 - Polyethylene Terephthalate Film, Sheet and Strip From Brazil: Preliminary Results of Antidumping...

    Science.gov (United States)

    2013-08-16

    ... International Trade Administration Polyethylene Terephthalate Film, Sheet and Strip From Brazil: Preliminary... response to requests from respondent Terphane Ltda. and from DuPont Teijin Films, Mitsubishi Polyester Film... terephthalate film, sheet and strip (PET film) from Brazil. The administrative review covers Terphane Ltda....

  13. 77 FR 20782 - Circular Welded Carbon Steel Pipes and Tubes From Thailand: Preliminary Results of Antidumping...

    Science.gov (United States)

    2012-04-06

    ... Pacific Pipe Preliminary Cost Memorandum. We revised Pacific Pipe's financial expense ratio calculation to... Saha Thai's G&A expense ratio to exclude profit from galvanizing services, duty refunds for hot-rolled... revised the denominator of the G&A expense ratio to include the cost of sales and services less...

  14. Preliminary results of UO2/Zircaloy-4 experiments under severe fuel damage conditions

    International Nuclear Information System (INIS)

    Chemical interactions between UO2 fuel and Zircaloy-4 cladding up to the melting point of zircaloy are described. Out-of-pile UO2/zircaloy reaction experiments have been performed to investigate the chemical interaction behavior under possible severe fuel damage conditions (very high temperatures and external overpressure). The tests have been conducted in inert gas (2 to 80 bar) with 10-cm long zircaloy cladding specimens filled with UO2 pellets. The annealing period varied between 1 and 150 minutes. The extent of the chemical reaction depends decisively on whether or not good contact between UO2 and zircaloy has been established. If solid contact exists, zircaloy reduces the UO2 to form oxygen-stabilized α-Zr(O) and uranium metal. The uranium reacts with zircaloy to form a (U,Zr) alloy rich in uranium. The (U,Zr) alloy, which is liquid above 1200 deg. C, lies between two α-Zr(O) layers. The UO2/zircaloy reaction obeys a parabolic rate law. The degree of the chemical interaction is determined by the extent of oxygen diffusion into the cladding, and hence by the time and temperature. The extent of oxygen diffusion into the cladding can be estimated by measuring the reaction layer thicknesses. Preliminary test results show good agreement with previous results at temperatures below 1500 deg. C. At higher temperatures and/or longer times, the parabolic dependence of the reaction layer thicknesses on time changes as the cladding becomes saturated with oxygen. The affinity of zirconium for oxygen, which results in an oxygen gradient across the cladding, is the driving force for the reaction. When oxygen-stabilized α-Zr(O) forms across the entire cladding wall, the oxygen gradient begins to level off, and the (U,Zr) alloy layer begins to disperse. The mechanical integrity of the oxidized specimens is quite low. On cooldown or during posttest handling, the highly embrittled specimens break into many pieces. The experiment results are used to model the UO2/zircaloy

  15. Performance assessment methodology and preliminary results for low-level radioactive waste disposal in Taiwan

    International Nuclear Information System (INIS)

    disposal system. Final performance assessment analyses will be used in the regulatory process of licensing a site. The SNL/INER team has developed a performance assessment methodology that is used to simulate processes associated with the potential release of radionuclides to evaluate these sites. The following software codes are utilized in the performance assessment methodology: GoldSim (to implement a probabilistic analysis that will explicitly address uncertainties); the NRC's Breach, Leach, and Transport - Multiple Species (BLT-MS) code (to simulate waste-container degradation, waste-form leaching, and transport through the host rock); the Finite Element Heat and Mass Transfer code (FEHM) (to simulate groundwater flow and estimate flow velocities); the Hydrologic Evaluation of Landfill performance Model (HELP) code (to evaluate infiltration through the disposal cover); the AMBER code (to evaluate human health exposures); and the NRC's Disposal Unit Source Term -- Multiple Species (DUST-MS) code (to screen applicable radionuclides). Preliminary results of the evaluations of the two disposal concept sites are presented

  16. 4-Ports endoscopic extraperitoneal radical prostatectomy: preliminary and learning curve results

    Directory of Open Access Journals (Sweden)

    Humberto do Nascimento Barbosa Junior

    2016-06-01

    Full Text Available ABSTRACT Introduction There is a lack of studies in our national scenario regarding the results obtained by laparoscopic radical prostatectomy technique (LRP. Except for a few series, there are no consistent data on oncological, functional, and perioperative results on LRP held in Brazil. As for the LRP technique performed by extraperitoneal access (ELRP, when performed by a single surgeon, the results are even scarcer. Objective To analyze the early perioperative and oncologic results obtained with the ELRP, throughout the technical evolution of a single surgeon. Patients and methods A non-randomized retrospective study was held in a Brazilian hospital of reference. In the 5-year period, 115 patients underwent the ELRP procedure. Patients were divided into two groups, the first 57 cases (Group 1 and the following 58 cases, (Group 2. A comparative analysis between the groups of efficacy results and ELRP safety was carried out. Results The average age of patients was 62.8 year-old and the PSA of 6.9ng/dl. The total surgery time was 135.8 minutes on average, and the urethral-bladder anastomosis was 21.9 min (23.3 min versus 20.7 min. The positive surgical margins (PSM rate was 17.1%, showing no difference between groups (16.4% versus 17.9%; p=0.835. There was statistical difference between the groups in relation to the anastomosis time, estimated blood loss and the withdrawal time of the urinary catheter. Conclusion The ELRP technique proved to be a safe and effective procedure in the treatment of prostate cancer, with low morbidity.

  17. 76 FR 41759 - Fresh Garlic From the People's Republic of China: Extension of Time Limit for Preliminary Results...

    Science.gov (United States)

    2011-07-15

    ... Revocation in Part, 75 FR 81565 (December 28, 2010). The preliminary results of this administrative review... International Trade Administration Fresh Garlic From the People's Republic of China: Extension of Time Limit for... garlic from the People's Republic of China covering the period November 1, 2009, through October 31,...

  18. 76 FR 12938 - Magnesium Metal From the Russian Federation: Extension of Time Limit for Preliminary Results of...

    Science.gov (United States)

    2011-03-09

    ... Antidumping and Countervailing Duty Administrative Reviews, 75 FR 29976 (May 28, 2010). On December 17, 2010... Federation: Extension of Time Limit for Preliminary Results of Antidumping Duty Administrative Review, 75 FR... Administrative Determination Deadlines Pursuant to the Tariff Act of 1930, As Amended, 70 FR 24533 (May 10,...

  19. 76 FR 17380 - Solid Urea From the Russian Federation: Extension of Time Limit for Preliminary Results of...

    Science.gov (United States)

    2011-03-29

    ... Administrative Review, 75 FR 53274 (August 31, 2010). The preliminary results of this administrative review are... International Trade Administration Solid Urea From the Russian Federation: Extension of Time Limit for... solid urea from the Russian Federation for the period July 1, 2009, through June 30, 2010....

  20. 76 FR 19049 - Certain Tissue Paper Products From the People's Republic of China: Notice of Preliminary Results...

    Science.gov (United States)

    2011-04-06

    ...: Bicycles From the People's Republic of China, 61 FR 19026 (April 30, 1996). Accordingly, we are treating... Preliminary Results of Antidumping Duty Administrative Review AGENCY: Import Administration, International...: Brian Smith or Gemal Brangman, AD/CVD Operations, Office 2, Import Administration, International...

  1. 76 FR 20312 - Certain Pasta From Turkey: Extension of Time Limit for the Preliminary Results of Antidumping...

    Science.gov (United States)

    2011-04-12

    ... Amended Final Determination of Sales at Less Than Fair Value: Certain Pasta From Turkey, 61 FR 38545 (July... Administrative Review, 75 FR 38074 (July 1, 2010). On July 30, 2010, we received a request from petitioners \\1... FR 53274 (August 31, 2010). The preliminary results of review are currently due April 4, 2011....

  2. 77 FR 11065 - Certain Pasta From Turkey: Extension of Time Limit for the Preliminary Results of the...

    Science.gov (United States)

    2012-02-24

    ... and Requests for Revocation in Part, 76 FR 53404 (August 26, 2011). The preliminary results of this... the Tariff Act of 1930, As Amended, 70 FR 24533 (May 10, 2005). Statutory Time Limits Section 751(a)(3... International Trade Administration Certain Pasta From Turkey: Extension of Time Limit for the...

  3. Reflectance anisotropy measurements using a pushbroom spectrometer mounted on UAV and a laboratory goniometer – preliminary results

    NARCIS (Netherlands)

    Suomalainen, J.; Roosjen, P.; Bartholomeus, H.; Clevers, J.

    2015-01-01

    During 2014–2015 we have developed a new method to measure reflectance factor anisotropy using a pushbroom spectrometer mounted on a multicopter UAV. In this paper/presentation we describe the acquisition method and show the preliminary results of the experiment. To validate the measurements the sam

  4. 78 FR 55676 - Certain Frozen Fish Fillets From the Socialist Republic of Vietnam: Preliminary Results of the...

    Science.gov (United States)

    2013-09-11

    ...: Certain Frozen Fish Fillets From the Socialist Republic of Vietnam, 68 FR 47909 (August 12, 2003) (``Order... calculated in accordance with section 772 of the Act. Because Vietnam is a non-market economy (``NME... Socialist Republic of Vietnam: Preliminary Results of Antidumping Duty Administrative Review, 71 FR...

  5. 77 FR 75998 - Lemon Juice from Mexico: Preliminary Results of Full Sunset Review of the Suspended Antidumping...

    Science.gov (United States)

    2012-12-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE International Trade Administration Lemon Juice from Mexico: Preliminary Results of Full Sunset Review of the..., Department of Commerce. DATES: Effective December 26, 2012. SUMMARY: On August 1, 2012, the Department...

  6. 75 FR 81221 - Stainless Steel Sheet and Strip in Coils From Mexico; Preliminary Results of the Five-Year...

    Science.gov (United States)

    2010-12-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE International Trade Administration Stainless Steel Sheet and Strip in Coils From Mexico; Preliminary Results of..., International Trade Administration, Department of Commerce. SUMMARY: On June 2, 2010, the Department of...

  7. 76 FR 44305 - Honey From Argentina: Extension of Time Limit for Preliminary Results of Antidumping Duty New...

    Science.gov (United States)

    2011-07-25

    .... (Villamora). See Honey from Argentina: Notice of Initiation of Antidumping Duty New Shipper Review, 76 FR... International Trade Administration Honey From Argentina: Extension of Time Limit for Preliminary Results of... initiation a new shipper review of the antidumping duty order on honey from Argentina, covering the period...

  8. Gaze behavior nonlinear dynamics assessed in virtual immersion as a diagnostic index of sexual deviancy: preliminary results

    OpenAIRE

    Renaud, Patrice; Chartier, Sylvain; Rouleau, Joanne-L.; Proulx, Jean; Trottier, Dominique; John P. Bradford; Fedoroff, Paul; Bouchard, Stéphane; Décarie, Jean

    2008-01-01

    This paper presents preliminary results about the use of virtual characters, penile plethysmography and gaze behaviour dynamics to assess deviant sexual preferences. Pedophile patients' responses are compared to those of non-deviant subjects while they were immersed with virtual characters depicting relevant sexual features.

  9. 77 FR 4543 - Certain Polyester Staple Fiber From Taiwan: Extension of Time Limit for Preliminary Results of...

    Science.gov (United States)

    2012-01-30

    ... for Revocation in Part, 76 FR 37781 (June 28, 2011). The preliminary results are currently due no... International Trade Administration Certain Polyester Staple Fiber From Taiwan: Extension of Time Limit for... antidumping duty order on certain polyester staple fiber from Taiwan for the period May 1, 2010, through...

  10. 76 FR 5331 - Certain Polyester Staple Fiber From Taiwan: Extension of Time Limit for Preliminary Results of...

    Science.gov (United States)

    2011-01-31

    ... for Revocation in Part, 75 FR 37759 (June 30, 2010). The preliminary results are currently due no... International Trade Administration Certain Polyester Staple Fiber From Taiwan: Extension of Time Limit for... antidumping duty order on certain polyester staple fiber from Taiwan for the period May 1, 2009, through...

  11. A cognitive behavioural group therapy for patients diagnosed with mild cognitive impairment and their significant others: feasibility and preliminary results

    NARCIS (Netherlands)

    Joosten-Weyn Banningh, L.W.A.; Kessels, R.P.C.; Olde Rikkert, M.G.M.; Geleijns-Lanting, C.E.

    2008-01-01

    Objective: To evaluate the feasibility and present preliminary results of a cognitive behavioural group therapy for patients with mild cognitive impairment and their significant others. Design: One group pretest-posttest design. Subjects: Twenty-two patients with mild cognitive impairment and their

  12. A cognitive behavioural group therapy for patients diagnosed with mild cognitive impairment and their significant others: feasibility and preliminary results.

    NARCIS (Netherlands)

    Joosten-Weyn Banningh, E.W.A.; Kessels, R.P.C.; Olde Rikkert, M.G.M.; Geleijns-Lanting, C.E.; Kraaimaat, F.W.

    2008-01-01

    OBJECTIVE: To evaluate the feasibility and present preliminary results of a cognitive behavioural group therapy for patients with mild cognitive impairment and their significant others. DESIGN: One group pretest-posttest design. SUBJECTS: Twenty-two patients with mild cognitive impairment and their

  13. Gaze behavior nonlinear dynamics assessed in virtual immersion as a diagnostic index of sexual deviancy: preliminary results

    Directory of Open Access Journals (Sweden)

    John P. Bradford

    2009-04-01

    Full Text Available This paper presents preliminary results about the use of virtual characters, penile plethysmography and gaze behaviour dynamics to assess deviant sexual preferences. Pedophile patients' responses are compared to those of non-deviant subjects while they were immersed with virtual characters depicting relevant sexual features.

  14. 75 FR 41439 - Lightweight Thermal Paper from Germany: Extension of Time Limits for the Preliminary Results of...

    Science.gov (United States)

    2010-07-16

    ... Request for Revocation in Part, 74 FR 68229 (December 23, 2009). The notice of the preliminary results is... Sales at Less Than Fair Value and Postponement of Final Determination, 73 FR 27498, 27502 (May 13, 2008... International Trade Administration Lightweight Thermal Paper from Germany: Extension of Time Limits for...

  15. External hyperalimentation: its role in radiotherapy/chemotherapy of lung cancer - a preliminary report

    International Nuclear Information System (INIS)

    Radiation and chemotherapy can result in further deterioration of the nutritional status of lung cancer patients who frequently are malnourished as a consequence of their underlying malignancy. Nutritional support of these individuals should be based on a complete assessment of each patient's requirements as well as providing such requirements through a safe efficacious eternal hyperalimentaton program. This investigation was designed to study whether clinically significant palliation maybe achieved by nutritional rehabilitation of the cachetic lung cancer patient as an adjuvant to conventional antitumor therapy. (auth.). 13 refs.; 4 tabs

  16. The diagnostic rules of peripheral lung cancer preliminary study based on data mining technique

    Institute of Scientific and Technical Information of China (English)

    Yongqian Qiang; Youmin Guo; Xue Li; Qiuping Wang; Hao Chen; Duwu Cui

    2007-01-01

    Objective: To discuss the clinical and imaging diagnostic rules of peripheral lung cancer by data mining technique, and to explore new ideas in the diagnosis of peripheral lung cancer, and to obtain early-stage technology and knowledge support of computer-aided detecting (CAD). Methods: 58 cases of peripheral lung cancer confirmed by clinical pathology were collected. The data were imported into the database after the standardization of the clinical and CT findings attributes were identified. The data was studied comparatively based on Association Rules (AR) of the knowledge discovery process and the Rough Set (RS) reduction algorithm and Genetic Algorithm(GA) of the generic data analysis tool (ROSETTA), respectively. Results: The genetic classification algorithm of ROSETTA generates 5 000 or so diagnosis rules. The RS reduction algorithm of Johnson's Algorithm generates 51 diagnosis rules and the AR algorithm generates 123 diagnosis rules. Three data mining methods basically consider gender, age,cough, location, lobulation sign, shape, ground-glass density attributes as the main basis for the diagnosis of peripheral lung cancer. Conclusion: These diagnosis rules for peripheral lung cancer with three data mining technology is same as clinical diagnostic rules, and these rules also can be used to build the knowledge base of expert system. This study demonstrated the potential values of data mining technology in clinical imaging diagnosis and differential diagnosis.

  17. Preliminary Results of Occurrence and Mineralogical Properties of Opals from Northwest part of Central Anatolia

    Science.gov (United States)

    Çalık, Ayten

    2016-04-01

    The study area, is located in northwest part of central Anatolian, consists of Eskişehir and Kütahya region where are important for finding occurrence of opaline silica mineralization as well as chalcedonic silica mineralization. In this study preliminary results of mineralogical properties of opals from four different area (Sabuncupınar, Belkavak, Gokçekısık and Derekoy), located between Eskisehir and Kutahya region, have been given. In the Kütahya region, dendritic opal nodules present in Pliocene pyroclastic rocks - Kanoturaǧı hill and white opals outcrop in stockwork veins with serpentinites in Küçükali hill around Sabuncupınar village. The mainly whitish - blue and gray opal nodules range from millimetres in diameter to about five and ten centimetres in Kanoturagı hill. White opals, called milky opal, are white color and present in veins within serpentinites. The Kanoturagı opal is made up of tiny spheres, the milky opal is made up tiny sphere with fibrous texture based on the SEM. Green opals present in Miocene pyroclastic rocks in Belkavak village. The Belkavak opals are greenish color and having a brecciated appearance. Opals outcrops around Sabuncu pınar and Belkavak villages consist of opal - CT, alpha quartz and, moganite, and a lesser amount of opal - C based on the results of XRD analysis. In the Eskişehir region, the dendritic opals occur as nodules in volcanogenetic conglomerates of Pliocene age in the Dereyalak area. The Dereyalak opals vary in size from millimetres in diameter to about ten centimetres. Their color are mainly white, beige, greenish, yellowish orange and black. On the other hand, Pliocene pyroclastic rocks are the host rock of opals in Gökçekısık village - Eskişehir. Gökçekısık Opals are mainly colorless, pale shades of yellow, whitish blue and gray colors and display a reinous to sub vitreous luster. Dereyalak dendiritic opals consist of opal - CT, opal - C and a lesser amount of alpha quartz and, moganite

  18. Effect of adipose tissue processing procedures in culture result: a study preliminary

    Directory of Open Access Journals (Sweden)

    Jeanne A. Pawitan

    2011-02-01

    Full Text Available Background: There are various methods of processing adipose tissue before culture, depending on the adipose tissue samples. The aim of this study is to compare several modifications of culturing and sub-culturing procedures of adipose tissue to fit the condition in our laboratory.Method: This is a descriptive study that was done in the Immunology and Endocrinology Integrated Laboratory, University of Indonesia, from  October 2009 to April 2010. Three adipose tissue processing procedures, various amount of seeding and two subculture methods were compared in term of cell yield and time needed. In the first procedure, collagenase-1 digestion was done in 30minutes, cell seeding were 24,000 and 36,000 per flask; in the second procedure, collagenase-1 digestion was done in 60minutes, cell seeding were 24,000, 48,000, and 72,000 per flask; and in the third procedure, the adipose tissue remnants from the first  procedure were again digested for another 45 minutes, cell seeding were 74,000, and 148,000 per flask. Difference in subculture methods were the presence or absence of washing step.Result: Procedure 1 yielded the lowest amount of cell, and after culture, the cells grew very slow, and was contaminated before harvest of primary culture. Procedure-2 and -3 succeeded to yield primary cultures. Some of the cultures were contaminated, so that further subculture was not  applicable, and only one tissue processing procedure (procedure 2: 60 minute collagenase-1 digestion, without lysis buffer, cell seeding 48,000 and 72,000 could complete the three subcultures. Though some of the procedures could not be completed, final result could be concluded.Conclusion: In this preliminary study, 60 minute colagenase-1 digestion with intermittent shaking every 5 minutes and cell seeding around 50,000 or more, followed by subculture method without washing step gave the best result. (Med J Indones 2011; 20:15-9Keywords: collagenase-1, primary culture, subculture

  19. Preliminary Study on Cytotoxic Effect of Biodegradation of Magnesium on Cancer Cells

    Institute of Scientific and Technical Information of China (English)

    Yu Zhang; Ling Ren; Mei Li; Xiao Lin; Huafu Zhao; Ke Yang

    2012-01-01

    Biodegradation of magnesium (Mg) based metals in body fluid can lead to a strong alkalinity as well as an increase of Mg2+ concentration in its surrounding environment. In vitro cytotoxic effects of the extracts of pure Mg with and without micro arc oxidation (MAO) coating on osteosarcoma U2-OS cells, a kind of bone cancer cells, were preliminarily studied, independently considering the increase of either alkalinity or Mg2+ concentration. The results indicated that the high alkalinity, i.e., a great increase of pH value, caused by the degradations of Mg with and without MAO coating in the culture medium all showed strong cytotoxic effects on U2-OS cells. However, the increase of Mg2+ concentration had no such cytotoxic effect. This finding may provide an alternative way to cure bone cancers through creating a high alkalinity surrounding the cancer cells.

  20. Development and preliminary evaluation of a rehabilitation consult for survivors of head and neck cancer: an intervention mapping protocol

    OpenAIRE

    McEwen, Sara E; Aileen M. Davis; Jones, Jennifer M; Martino, Rosemary; Poon, Ian; Rodriguez, Ana Maria; Ringash, Jolie

    2015-01-01

    Background Evidence suggests that rehabilitation interventions can improve function and quality of life in survivors of head and neck cancer (HNC), but there is a lack of coordinated, integrated services, and those offered are inconsistent. To address these gaps, we will develop and conduct preliminary evaluation of a rehabilitation consult, built on the theoretical foundations of goal setting and self-management, and composed of a brief functional evaluation, a resource compendium, and colla...